Science.gov

Sample records for 1984-1990 ten-year results

  1. Propellant/material compatibility program and results: Ten-year milestones

    NASA Technical Reports Server (NTRS)

    Moran, C.; Bjorkland, R.

    1982-01-01

    The analyses and results of a test program to establish the effects of long term (10 years or more) contact of materials with earth-storable propellants for the purpose of designing chemical propulsion system components which are used for current as well as future planetary spacecraft are described. The period from the publication of JPL TM 33-779 IN 1976 through the testing accomplished in 1981 is covered. The following propellants are reported herein: hydrazine, monomethylhydrazine and nitrogen tetroxide. Materials included the following: aluminum alloys, corrosion resistant steels and a titanium alloy. The results of the testing of more than 80 specimens are included. Material ratings relative to the ten year milepost were assigned. Some evidence of propellant decomposition was found. Titanium is rated as acceptable for ten year applications. Aluminum and stainless steel alloys are also rated as acceptable with few restrictions.

  2. Ten-year results of quality assurance in radiotherapy chart round

    PubMed Central

    2013-01-01

    Background The Royal Australian and New Zealand College of Radiologists (RANZCR) initiated a unique instrument to audit the quality of patient notes and radiotherapy prescriptions. We present our experience collected over ten years from the use of the RANZCR audit instrument. Methods In this study, the results of data collected prospectively from January 1999 to June 2009 through the audit instrument were assessed. Radiotherapy chart rounds were held weekly in the uro-oncology tumour stream and real time feedback was provided. Electronic medical records were retrospectively assessed in September 2009 to see if any omissions were subsequently corrected. Results In total 2597 patients were audited. One hundred and thirty seven (5%) patients had one hundred and ninety nine omissions in documentation or radiotherapy prescription. In 79% of chart rounds no omissions were found at all, in 12% of chart rounds one omission was found and in 9% of chart rounds two or more omissions were found. Out of 199 omissions, 95% were of record keeping and 2% were omissions in the treatment prescription. Of omissions, 152 (76%) were unfiled investigation results of which 77 (51%) were subsequently corrected. Conclusions Real-time audit with feedback is an effective tool in assessing the standards of radiotherapy documentation in our department, and also probably contributed to the high level of attentiveness. A large proportion of omissions were investigation results, which highlights the need for an improved system of retrieval of investigation results in the radiation oncology department. PMID:23617328

  3. Ten-year results of a double-heat-treated metal-on-metal hip resurfacing.

    PubMed

    Daniel, J; Ziaee, H; Kamali, A; Pradhan, C; Band, T; McMinn, D J W

    2010-01-01

    Second-generation metal-on-metal bearings were introduced as a response to the considerable incidence of wear-induced failures associated with conventional replacements, especially in young patients. We present the results at ten years of a consecutive series of patients treated using a metal-on-metal hip resurfacing. A distinct feature of the bearings used in our series was that they had been subjected to double-heat treatments during the post-casting phase of their manufacture. In the past these bearings had not been subjected to thermal treatments, making this a unique metal-on-metal bearing which had not been used before in clinical practice. We report the outcome of 184 consecutive hips (160 patients) treated using a hybrid-fixed metal-on-metal hip resurfacing during 1996. Patients were invited for a clinicoradiological follow-up at a minimum of ten years. The Oxford hip score and anteroposterior and lateral radiographs were obtained. The mean age at operation was 54 years (21 to 75). A series of 107 consecutive hips (99 patients) who received the same prosthesis, but subjected to a single thermal treatment after being cast, between March 1994 and December 1995, were used as a control group for comparison. In the 1994 to 1995 group seven patients (seven hips) died from unrelated causes and there were four revisions (4%) for osteolysis and aseptic loosening. In the 1996 group nine patients died at a mean of 6.9 years after operation because of unrelated causes. There were 30 revisions (16%) at a mean of 7.3 years (1.2 to 10.9), one for infection at 1.2 years and 29 for osteolysis and aseptic loosening. Furthermore, in the latter group there were radiological signs of failure in 27 (24%) of the 111 surviving hips. The magnitude of the problem of osteolysis and aseptic loosening in the 1996 cohort did not become obvious until five years after the operation. Our results indicate that double-heat treatments of metal-on-metal bearings can lead to an increased

  4. Ten years of photonics education at the college level in Ontario: results and by-products

    NASA Astrophysics Data System (ADS)

    Nantel, Marc

    2010-08-01

    In 2000, there was no way for an Ontario student to obtain a credential in optics, laser or photonics without going through graduate school. This was in, arguably, the world-leading jurisdiction in photonics-enabled telecommunications industry. To alleviate this problem and supply the job market with highly-qualified people in the field of optics and photonics, the Ontario Centres of Excellence - then as Photonics Research Ontario - partnered with Algonquin College (Ottawa) and Niagara College (Welland) to establish over the past decade a suite of programs: a 1-year Certificate in Advanced Lasers, a 2-year Diploma for Photonics Engineering Technician, a 3-year Diploma for Photonics Engineering Technologists and a 4-year Bachelor of Applied Technology - Photonics. Much has been learnt along the way - the crucial need for industrial partner and government support, for example - and many course corrections had to be made (telecom bust, anyone?). The author will share the results of this 10-year journey so far, the lessons learnt, and a view to the next ten years for these programs and photonics education in Ontario in general.

  5. Ten Years of Results of Modified Frontalis Muscle Transfer for the Correction of Blepharoptosis

    PubMed Central

    Kim, Woo Jeong; Park, Dae Hwan

    2016-01-01

    Background Conventional frontalis transfer may cause a range of complications. In order to overcome complications, we made modifications to the surgical technique, and compared the outcomes of patients who underwent conventional frontalis transfer with those of patients who underwent modified frontalis transfer. Methods We conducted a retrospective study of 48 patients (78 eyes) who underwent conventional frontalis transfer between 1991 and 2003 (group A) and 67 patients (107 eyes) who underwent modified frontalis transfer between 2004 and 2014 (group B). The frontalis transfer procedures were modified conform to the following principles. The tip of the frontalis muscle flap included soft tissue that was as thick as possible and the soft tissue on the tarsal plate was removed to the greatest extent possible. A double fold was created in cases of unilateral ptosis. In order to evaluate the objective effects of modification, preoperative and postoperative values of the marginal distance reflex 1 (MRD1), the corneal exposure area, and the decrease in eyebrow height were compared between the two groups. Results In group A, patients showed an improvement of 1.19 mm in the MRD1, a 6.31% improvement in the corneal exposure area, and a 7.82 mm decrease in eyebrow height. In group B, patients showed an improvement of 2.17 mm in the MRD1, an 8.39% improvement in the corneal exposure area, and an 11.54 mm decrease in eyebrow height. The improvements in group B were significantly greater than those in group A. Conclusions Modified frontalis transfer showed better results than the conventional procedure and provided satisfactory outcomes. PMID:27019810

  6. Ten years of laser treatment of congenital vascular disorders: techniques and results

    NASA Astrophysics Data System (ADS)

    Philipp, Carsten M.; Berlien, Hans-Peter; Poetke, Margitta; Waldschmidt, Juergen

    1994-12-01

    During the period of January 1984 - July 1993, we have treated 611 children with more than 2000 lesions of congenital vascular disorders (CVD) such as hemangiomas and vascular malformations. This number does not include the patients with port wine stains, which also have been treated by means of laser. Most of the CVD patients (n equals 467) presented hemangiomas of the face, the anogenital region, and the extremities, some were located in the trachea or mouth or in the urogenital tract. All of these hemangiomas were growing prior to intervention or showed complications such as bleeding, ulceration, superinfection, or obstruction. Nearly a quarter (n equals 144) of the patients presented vascular malformations, either of singular vessel type involvement or of mixed vascular genesis (venous, arterio- venous, veno-lymphatic or lymphatic) with various complications like tracheal obstruction or recurrent thrombophlebitis. According to our step program, which is based on a clinical classification, the hemangiomas were treated as early as possible, while the vascular malformations were only treated with laser when no other therapeutic technique (embolization, resection) was suitable. All patients were referred for laser treatment from other centers. The lasers used were Nd:YAG and Argon lasers with transcutaneous application with or without continuous ice-cube surface cooling or interstitial laser application. The treatments were performed either on in- or outpatient basis according to age, localization and with good to excellent results in most cases and a complication rate of less than 2%.

  7. Femoral revision with taper stems: results at ten years follow-up.

    PubMed

    Cherubino, Paolo; Fagetti, Alessandro; D'Angelo, Fabio; Surace, Michele Francesco

    2010-10-01

    In the case of extensively damaged meta-diaphyseal femoral bone with cortices thinning and widened femoral canal, tapered stems allow a good primary fixation and early weight-bearing. A retrospective review was conducted to evaluate long-term results of modular revision taper stems implanted from March 1999 to December 2002. Sixty-five consecutive hip revision surgeries were performed, mostly for aseptic loosening (75% of the cases). Femoral bone stock defects were classified according to AAOS's criteria and consisted mainly in type II (cavitary defects, 44.6%) and type III (combined defects, 33.9%). A trochanteric osteotomy was performed in 25 cases (38%) to remove primary implants that were cemented in 35 cases (54%). The mean postoperative follow-up was 109 months (range, 76 to 131 months). Clinical assessment at follow-up showed a significantly improved mean Harris Hip Score from 42 points preoperatively to 81 points postoperatively, while the x-ray examination did show a satisfactory distal integration of the stem in all cases and satisfactory reconstitution of the femoral bone stock in 47% of cases. The average subsidence of the stem at follow-up was less than one millimeter. According to data analysis, a leg-length discrepancy exceeding 15 millimeters caused significantly worse functional outcome and pain.

  8. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study.

    PubMed Central

    Siewert, J R; Böttcher, K; Stein, H J; Roder, J D

    1998-01-01

    OBJECTIVE: In 1986 a prospective multicenter observation trial in patients with resected gastric cancer was initiated in Germany. An analysis of prognostic factors based on the 10-year survival data is now presented. PATIENTS AND METHODS: A total of 1654 patients treated for gastric cancer between 1986 and 1989 at 19 centers in Germany and Austria were included. The resected specimen were evaluated histopathologically according to a standardized protocol. The extent of lymphadenectomy was classified after surgery based on the number of removed lymph nodes on histopathologic assessment (25 or fewer removed nodes, D1 or standard lymphadenectomy; >25 removed nodes, D2 or extended lymphadenectomy). Endpoint of the study was death. Follow-up is complete for 97% of the included patients (median follow-up of the surviving patients is 8.4 years). Prognostic factors were assessed by multivariate analysis. RESULTS: A complete macroscopic and microscopic tumor resection (R0 resection according to the UICC 1997) could be achieved in 1182 of the 1654 patients (71.5%). The calculated 10-year survival rate in the entire patient population was 26.3% +/- 4.7%; it was 36.1% +/- 1.6% after an R0 resection. In the total patient population there was an independent prognostic effect of the ratio between invaded and removed lymph nodes, the residual tumor (R) category, the pT category, the presence of postsurgical complications, and the presence of distant metastases. Multivariate analysis in the subgroup of patients who had a UICC R0 resection confirmed the nodal status, the pT category, and the presence of postsurgical complications as the major independent prognostic factors. The extent of lymph node dissection had a significant and independent effect on the 10-year survival rate in patients with stage II tumors. This effect was present in the subgroups with (pT2N1) and without (pT3N0) lymph node metastases on standard histopathologic assessment. The beneficial effect of extended

  9. Color measurements on marble and limestone briquettes exposed to outdoor environment in the Eastern United States. Volume I: Results of exposure 1984-1990

    SciTech Connect

    Reimann, K.J.

    1994-04-01

    In a long-term program that began in 1984, limestone and marble briquettes have been exposed to both anthropogenic acid deposition and natural weathering at four field sites in the eastern United States. Similar tests began at an Ohio site in 1986. Effects of exposure on the briquettes and other materials at the sites are evaluated periodically by several federal agencies cooperating in the National Acid Precipitation Assessment Program (NAPAP). One of the primary contributions of Argonne National Laboratory to the NAPAP has been the measurement of tristimulus color change on samples exposed to the environment. Results from the first six years indicate a yellowing of the marble and a darkening of limestone on both the skyward and groundward surfaces of fresh and preexposed briquettes. The relationship between discoloration and exposure period appears to be linear. Discoloration rates as a function of a cumulative exposure time are almost constant for marble and slightly decreasing for limestone Dark spots on groundward surfaces were measured with tristimulus color equipment prior to chemical analysis to determine if a correlation exists between darkening (change in reflectance) and SO{sub 4} concentration. Taking exposure time into consideration, and assuming that the airborne concentration of dark particles, which cause darkening, is proportional to airborne SO{sub 2} concentration, one can establish a linear relationship between exposure time, darkening, and SO{sub 2} concentration. The program is continuing so that additional data can be obtained.

  10. The Canadian Arctic Atmospheric Chemistry Experiment (ACE) Validation Project: Overview and results from ten years of ACE operations

    NASA Astrophysics Data System (ADS)

    Walker, Kaley; Strong, Kimberly

    2014-05-01

    As of February 2014, the Canadian-led Atmospheric Chemistry Experiment (ACE) satellite mission has been making measurements of the Earth's atmosphere for ten years. As ACE operations have extended beyond the initial two-year mission, there is a continuing need to validate the trace gas data products from the ACE-Fourier Transform Spectrometer (ACE-FTS) and the Measurement of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation (ACE-MAESTRO) instruments. Ground-based measurements provide critical data for the validation of satellite retrievals of trace gases and for the assessment of long-term stability of these measurements. In particular, validation comparisons are needed for ACE during Arctic springtime to understand better the measurements of species involved in stratospheric ozone chemistry. To this end, eleven Canadian Arctic Atmospheric Chemistry Experiment (ACE) Validation Campaigns have been conducted during the spring period (February - April in 2004 - 2014) at the Polar Environment Atmospheric Research Laboratory (PEARL) in Eureka, Nunavut (80°N, 86°W). This period coincides with the most chemically active time of year in the Arctic, as well as a significant number of satellite overpasses. A suite of as many as 12 ground-based instruments, as well as frequent balloon-borne ozonesonde and radiosonde launches, have been used in each campaign. These instruments include: a ground-based version of the ACE-FTS (PARIS - Portable Atmospheric Research Interferometric Spectrometer), a terrestrial version of the ACE-MAESTRO, a SunPhotoSpectrometer, two zenith-viewing UV-visible grating spectrometers, a Bomem DA8 Fourier transform spectrometer, a Bruker 125HR Fourier transform spectrometer, a Systeme d'Analyse par Observations Zenithales (SAOZ) instrument, and several Brewer spectrophotometers. In the past several years, these results have been used to validate the measurements by the ACE-FTS and ACE-MAESTRO instruments on SCISAT as well

  11. Affordances: Ten Years On

    ERIC Educational Resources Information Center

    Brown, Jill P.; Stillman, Gloria

    2014-01-01

    Ten years ago the construct, affordance, was rising in prominence in scholarly literature. A proliferation of different uses and meanings was evident. Beginning with its origin in the work of Gibson, we traced its development and use in various scholarly fields. This paper revisits our original question with respect to its utility in mathematics…

  12. Ten years of PAMELA

    NASA Astrophysics Data System (ADS)

    Spillantini, Piero

    2016-07-01

    PAMELA results obtained in the ten years of data taking and activity must include other important new measurements, opening the era of precise measurements in cosmic ray observation, such as light elements and isotopes fluxes, the absolute fluxes of protons and antiprotons and light nuclei, and of electrons and positrons, the discovery of a belt of antiprotons trapped in the terrestrial magnetic field, and in the SAA in particular, the fluxes of quasi-trapped electrons and positrons, the time evolution of the energetic tail of spectra of protons and helium nuclei in the powerful solar event of December 13th 2006, and other magnetosphere and solar physics observations. For the future, it must be mentioned the continuation of the activity of PAMELA team. The satellite orbit spans over a significantly large region of the Earth's magnetosphere, making possible a detailed study of its effect on the incoming radiation, in particular in the niche of the observations on the hundred MeV/n and a few GeV/n, where the low energy threshold of the instrument, the precision of the magnetic spectrometer and the resumed activity of the Sun promises to play an important role besides the explores operating in our region of the solar system.

  13. Oxford phase 3 unicompartmental knee arthroplasty in Japan--clinical results in greater than one thousand cases over ten years.

    PubMed

    Yoshida, Kenjiro; Tada, Masahiro; Yoshida, Hirokazu; Takei, Satoshi; Fukuoka, Shinichi; Nakamura, Hiroaki

    2013-10-01

    There are few reports of the Oxford unicompartmental knee arthroplasty (UKA) survival rate in Asia. This study describes outcomes of 1279 Oxford UKAs for Japanese patients. The mean follow-up was 5.2 years. We divided patients into two groups based on preoperative indications (extended indications group and strict indications group). The Oxford knee score improved from 22.3 to 40.8 (P=0.041). The 10-year survival rate using revision was 95%. A total of 25 UKAs (2.0%) required revision. The most common reason was subsidence of tibial component. The 5-year cumulative survival rate of the strict indications group was significantly higher than that of the extended indications group (99.1% vs. 93.8%, P<0.001). When we followed inclusion criteria strictly, good clinical results were achieved in Asia.

  14. Assessment of Ten-Year-Long Results of Kidney Biopsies Performed on Children in the Thrace Region of Turkey

    PubMed Central

    Özkayın, Neşe; Çıplak, Gökçe; Usta, Ufuk; Gençhellaç, Hakan; Temizöz, Osman

    2016-01-01

    Background Many children with kidney diseases can be diagnosed and treated without a biopsy. However, biopsy is a valuable method for the diagnostic and prognostic evaluation of children with kidney diseases. Aims To evaluate the clinical and pathological profiles of the kidney biopsies in our department to provide epidemiological data for clinical practice. Study Design Retrospective cross-sectional study. Methods Kidney biopsies and patient’s charts in pediatric patients performed between May 2005 and February 2015 at the Pediatric Nephrology Department, Trakya University School of Medicine were assessed retrospectively. Results A total of 100 patients were examined. Their mean age was 9.62±4.26 years (range: 1–17 years); 54% of the patients were girls and 46% were boys. The most frequent indication for kidney biopsy was nephrotic syndrome (33%). The most common kidney disease was primary glomerulonephritis, which was observed in 65% of cases. IgA nephropathy (24%) was the most frequently observed subtype in primary glomerulonephritis groups. Secondary glomerulonephritis was diagnosed in 35% of cases. Systemic lupus erythematosus (51%) was the most frequently observed subtype in the secondary glomerulonephritis groups. Conclusion IgA nephropathy and systemic lupus erythematosus were the most frequent primary and secondary glomerulonephritis in our region among children, respectively. PMID:27994909

  15. Recovery Potential of a Western Lowland Gorilla Population following a Major Ebola Outbreak: Results from a Ten Year Study

    PubMed Central

    Gatti, Sylvain; Levréro, Florence; Bigot, Elodie; Caillaud, Damien; Pierre, Jean-Sébastien; Ménard, Nelly

    2012-01-01

    Investigating the recovery capacity of wildlife populations following demographic crashes is of great interest to ecologists and conservationists. Opportunities to study these aspects are rare due to the difficulty of monitoring populations both before and after a demographic crash. Ebola outbreaks in central Africa have killed up to 95% of the individuals in affected western lowland gorilla (Gorilla gorilla gorilla) populations. Assessing whether and how fast affected populations recover is essential for the conservation of this critically endangered taxon. The gorilla population visiting Lokoué forest clearing, Odzala-Kokoua National Park, Republic of the Congo, has been monitored before, two years after and six years after Ebola affected it in 2004. This allowed us to describe Ebola's short-term and long-term impacts on the structure of the population. The size of the population, which included around 380 gorillas before the Ebola outbreak, dropped to less than 40 individuals after the outbreak. It then remained stable for six years after the outbreak. However, the demographic structure of this small population has significantly changed. Although several solitary males have disappeared, the immigration of adult females, the formation of new breeding groups, and several birth events suggest that the population is showing potential to recover. During the outbreak, surviving adult and subadult females joined old solitary silverbacks. Those females were subsequently observed joining young silverbacks, forming new breeding groups where they later gave birth. Interestingly, some females were observed joining silverbacks that were unlikely to have sired their infant, but no infanticide was observed. The consequences of the Ebola outbreak on the population structure were different two years and six years after the outbreak. Therefore, our results could be used as demographic indicators to detect and date outbreaks that have happened in other, non-monitored gorilla

  16. A ten years follow-up of the results of surgery for Dupuytren's disease. A study of fifty-eight cases.

    PubMed

    Norotte, G; Apoil, A; Travers, V

    1988-01-01

    Fifty-eight patients (52 males and 6 females) operated on for Dupuytren contracture were examined by the same author with a more than ten year follow-up. At time of surgery the average was 55 years old. 69 hands (169 fingers) rated 4.33 according to the simplified Tubiana's score were treated by the same operative procedure: Mac Indoe's incision, digital Z plasty (if needed), subtotal fasciectomy and physiotherapy beginning 8 days postoperatively. At long term, recurrence appears for 49 hands (71%) one every two in the two first postoperative years, one out of five after five years. 24 of them were graded stage I. The recurrence appeared 14 times associated with an extension of the disease and the earlier, the higher was the initial stage. Some factors seem to be of a bad prognosis regarding recurrence: age (93% of recurrence under 50 years old) Ledderhose or Lapeyronie (100%) other associated diseases (Alcoholism, diabetes mellitus, epilepsy) and severe preoperative stage. Subjective results are good: 45 patients are satisfied and only 3 underwent a second operation.

  17. A Ten-Year Reflection

    ERIC Educational Resources Information Center

    Phillip, Cyndi

    2016-01-01

    Five initiatives launched during Cyndi Phillip's term as American Association of School Librarians (AASL) President (2006-2007) continue to have an impact on school librarians ten years later. They include the rewriting of AASL's learning standards, introduction of the SKILLS Act, the presentation of the Crystal Apple Award to Scholastic Library…

  18. Titan's surface at 2.18-cm wavelength imaged by the Cassini RADAR radiometer: Results and interpretations through the first ten years of observation

    NASA Astrophysics Data System (ADS)

    Janssen, M. A.; Le Gall, A.; Lopes, R. M.; Lorenz, R. D.; Malaska, M. J.; Hayes, A. G.; Neish, C. D.; Solomonidou, A.; Mitchell, K. L.; Radebaugh, J.; Keihm, S. J.; Choukroun, M.; Leyrat, C.; Encrenaz, P. J.; Mastrogiuseppe, M.

    2016-05-01

    A comprehensive calibration and mapping of the thermal microwave emission from Titan's surface is reported based on radiometric data obtained at 2.18-cm wavelength by the passive radiometer included in the Cassini RADAR instrument. Compared to previous work, the present results incorporate the much larger data set obtained in the approximately ten years following Saturn Orbit Insertion. Brightness temperature data including polarization were accumulated by segments in Titan passes from Ta (October 2004) through T98 (February 2014). The observational segments were analyzed to produce a mosaic of effective dielectric constant based on the measurement of thermal polarization covering 76% of the surface, and brightness temperature at normal incidence covering Titan's entire surface. As part of the mosaicking process we also solved for the seasonal variation of physical temperature with latitude, which we found to be smaller by a factor of 0.87 ± 0.05 in relative amplitude compared to that reported in the thermal infrared by Cassini's Composite Infrared Spectrometer (CIRS). We used the equatorial temperature obtained by the Huygens probe and the seasonal dependence with latitude from CIRS to convert the brightness mosaic to absolute emissivity, from which we could infer global thermophysical properties of the surface in combination with the dielectric mosaic. We see strong evidence for subsurface (volume) scattering as a dominant cause of the radar reflectivity in bright regions, and elsewhere a surface composition consistent with the slow deposition and processing of organic compounds from the atmosphere. The presence of water ice in the near subsurface is strongly indicated by the high degree of volume scattering observed in radar-bright regions (e.g., Hummocky/mountainous terrains) constituting ∼10% of Titan's surface. A thermal analysis allowed us to infer a mean 2.18-cm emission depth in the range 40-100 cm for the dominant radar-dark terrains (the remainder of

  19. Ten Years Of PACS Experience

    NASA Astrophysics Data System (ADS)

    Hindel, Robert; Meyer-Ebrecht, Dieter; Heu, Ruettger; Oosterwijk, Herman

    1989-05-01

    A few of us here can look back ten years or more of having observed or even having participated in the PACS development. Depending on our point of view, little or much progress has been made since 1978. In the following, the authors will sketch a log book of an industrial developer and vendor, i.e., Philips Medical Systems. Some comments will turn out to be specifically applicable to the Philips Concern but the majority is probably also true for other major X-ray manufacturing companies. There are certain ground rules which have to be observed if a company wants to prove itself in a market as ambitious and complex as the medical market and, in particular, the PACS market. These ground rules will be either explicitly mentioned or are implied for the attentive listener. The following aspects will be considered:

  20. Ten Years of LibQual: A Study of Qualitative and Quantitative Survey Results at the University of Mississippi 2001-2010

    ERIC Educational Resources Information Center

    Greenwood, Judy T.; Watson, Alex P.; Dennis, Melissa

    2011-01-01

    This article analyzes quantitative adequacy gap scores and coded qualitative comments from LibQual surveys at the University of Mississippi from 2001 to 2010, looking for relationships between library policy changes and LibQual results and any other trends that emerged. Analysis found no relationship between changes in policy and survey results…

  1. Fibreoptic bronchoscopy: ten years on.

    PubMed Central

    Mitchell, D M; Emerson, C J; Collyer, J; Collins, J V

    1980-01-01

    Fibreoptic bronchoscopy was introduced more than 10 years ago and is now in many centres a routine diagnostic procedure, having superseded rigid bronchoscopy. Its major role is in the diagnosis of bronchial carcinoma, where the results are as good as, if not better than, results with the rigid instrument. Other major applications have been found in investigating haemoptysis, transbronchial lung biopsy in interstitial lung disease, and in the critically ill patient in the intensive care unit. More recently, the instrument has been used to perform bronchoalveolar lavage in investigating interstitial lung diseases and to enable lobar and segmental lung function studies to be performed. Fibreoptic bronchoscopy is a major advance in the diagnosis of pulmonary diseases, but there will always be times when rigid bronchoscopy is preferable. PMID:7000258

  2. Ten Year Operating Test Results and Post-Test Analysis of a 1/10 Segment Stirling Sodium Heat Pipe, Phase III

    NASA Technical Reports Server (NTRS)

    Rosenfeld, John, H; Minnerly, Kenneth, G; Dyson, Christopher, M.

    2012-01-01

    High-temperature heat pipes are being evaluated for use in energy conversion applications such as fuel cells, gas turbine re-combustors, Stirling cycle heat sources; and with the resurgence of space nuclear power both as reactor heat removal elements and as radiator elements. Long operating life and reliable performance are critical requirements for these applications. Accordingly, long-term materials compatibility is being evaluated through the use of high-temperature life test heat pipes. Thermacore, Inc., has carried out a sodium heat pipe 10-year life test to establish long-term operating reliability. Sodium heat pipes have demonstrated favorable materials compatibility and heat transport characteristics at high operating temperatures in air over long time periods. A representative one-tenth segment Stirling Space Power Converter heat pipe with an Inconel 718 envelope and a stainless steel screen wick has operated for over 87,000 hr (10 yr) at nearly 700 C. These life test results have demonstrated the potential for high-temperature heat pipes to serve as reliable energy conversion system components for power applications that require long operating lifetime with high reliability. Detailed design specifications, operating history, and post-test analysis of the heat pipe and sodium working fluid are described.

  3. Ten Years of Near-Surface-Sensitive Satellite Observations of Carbon Dioxide and Methane: Selected Results Related to Natural and Anthropogenic Sources and Sinks

    NASA Astrophysics Data System (ADS)

    Buchwitz, M. A.; Reuter, M.; Schneising, O.; Bovensmann, H.; Burrows, J. P.

    2014-12-01

    Prior to the recently successfully launched OCO-2 mission, global near-surface-sensitive satellite observations of carbon dioxide (CO2) have been made with SCIAMACHY/ENVISAT during 2002-2012 and are still being made since 2009 with TANSO-FTS/GOSAT, which also deliver atmospheric methane (CH4). The SCIAMACHY and GOSAT overlapping time series of atmospheric column-averaged mole fractions, i.e., XCO2 and XCH4, now cover more than 10 years. During the last years significant progress has been made in improving the quality of the XCO2 and XCH4 data products retrieved from SCIAMACHY and GOSAT and in extending the time series so that more and more applications can be addressed. In this presentation we present some recent results related to CO2 and CH4 sources and sinks. The SCIAMACHY products have been generated using retrieval algorithms developed at University of Bremen. For XCO2 we use an ensemble of data products generated using GOSAT retrieval algorithms developed in Japan (at NIES), in the US (at NASA/JPL and collaborating institutes) and at European institutions (University of Leicester, UK, and SRON, Netherlands, in collaboration with KIT, Germany). Focus will be on three applications: (i) An assessment of the strength of the European terrestrial carbon sink during 2003-2010 based on an ensemble of SCIAMACHY (2003-2010) and GOSAT (2010) XCO2 data products, (ii) an assessment of CO2 and NO2 anthropogenic emission and emission ratio trends using co-located SCIAMACHY XCO2 and NO2 observations over Europe, North America and East Asia, and (iii) an analysis of SCIAMACHY XCH4 retrievals during 2006-2011 over North America focusing on fugitive methane emissions from oil and gas production using tight geological formations ("fracking"). It will be shown that (i) the European terrestrial carbon sink appears to be stronger than expected, (ii) that recent Chinese CO2 and NO2 emissions are increasing but with a trend towards reduced NO2-to-CO2 emission ratios pointing to

  4. 'Safe handling of nanotechnology' ten years on

    NASA Astrophysics Data System (ADS)

    Maynard, Andrew D.; Aitken, Robert J.

    2016-12-01

    In 2006, a group of scientists proposed five grand challenges to support the safe handling of nanotechnology. Ten years on, Andrew Maynard and Robert Aitken -- two of the original authors -- look at where we have come, and where we still need to go.

  5. Preparing Future Faculty: Ten Years Later

    ERIC Educational Resources Information Center

    Murphy, Sean P.; Aiossa, Elizabeth; Winter, Mary Mugica

    2010-01-01

    When Sean Murphy designed the Graduate Student Internship Program at the College of Lake County (CLC), his 2001 TETYC article about the then two-year-old program detailed his programmatic response to the job market. Ten years later, the CLC-DePaul University partnership remains the strongest of the original dozen cross-sector relationships CLC…

  6. Ten years of commercial photovoltaic experience

    SciTech Connect

    Yerkes, J.W.

    1983-08-01

    This paper reviews the author's experience during the ten year period 1972 to 1982. Examples of type and size of photovoltaic systems deployed each year year during this period are given. A table of average photovoltaic module prices and volume is summarized at the end of the paper.

  7. Anxiety and IBS revisited: ten years later

    PubMed Central

    POPA, STEFAN-LUCIAN; DUMITRASCU, DAN LUCIAN

    2015-01-01

    Background and aim Irritable bowel syndrome (IBS) has been associated with high prevalence of psychological and psychiatric disorders. However, the association between IBS and each of its subtypes (diarrhea IBS-D, constipation IBS-C, mixed IBS-M) with anxiety still remains unclear. The purpose of this study was to perform a comparative analysis of the association between anxiety and IBS on a period of ten years. Methods PubMed was searched for studies analyzing IBS and anxiety, published at 10 years interval. The study presents a comparative analysis of the articles that were published between 2003–2005 and 2013–2015, investigating the correlation between anxiety and IBS. Results The initial search identified 220 articles, from which 156 were published between 2013 and 2015, and 64 were published between 2003 and 2005. Of these articles, 15 articles were included in the review. Out of these 15 articles, 10 articles analyzed the correlation between anxiety-depression status in IBS patients using specific questionnaires, 2 articles analyzed genetic variables in IBS, 1 article analyzed serotonin and monoamine oxidase levels in IBS, 1 article analyzed serum levels of IL-1β and IL-10 in IBS, 1 article analyzed somatostatin and vasoactive intestinal peptide levels in IBS. The result was a review of 15 studies that analyzed the association between IBS and anxiety. Conclusions IBS is a heterogeneous disorder caused by numerous psychological, immunological, infectious, endocrine and genetic factors. In recent years, the number of studies concentrating on genetic factors, cytokines and hormones has increased in comparison with the 2003–2005 period, when clinical investigation, using mainly questionnaires was the essential method. Also, the total number of papers investigating anxiety and IBS, considerably increased. The recent studies have confirmed the fact that IBS symptoms are often exacerbated during stressful events and the psychiatric treatment has a positive

  8. Ten-Year Changes in the Prevalence and Socio-Demographic Determinants of Physical Activity among Polish Adults Aged 20 to 74 Years. Results of the National Multicenter Health Surveys WOBASZ (2003-2005) and WOBASZ II (2013-2014)

    PubMed Central

    Kwaśniewska, Magdalena; Pikala, Małgorzata; Bielecki, Wojciech; Dziankowska-Zaborszczyk, Elżbieta; Rębowska, Ewa; Kozakiewicz, Krystyna; Pająk, Andrzej; Piwoński, Jerzy; Tykarski, Andrzej; Zdrojewski, Tomasz; Drygas, Wojciech

    2016-01-01

    Introduction The aim of the study was to estimate ten-year changes in physical activity (PA) patterns and sociodemographic determinants among adult residents of Poland. Methods The study comprised two independent samples of randomly selected adults aged 20–74 years participating in the National Multicentre Health Survey WOBASZ (2003–2005; n = 14572) and WOBASZ II (2013–2014; n = 5694). In both surveys the measurements were performed by six academic centers in all 16 voivodships of Poland (108 measurement points in each survey). Sociodemographic data were collected by an interviewer-administered questionnaire in both surveys. Physical activity was assessed in three domains: leisure-time, occupational and commuting physical activity. Results Leisure-time PA changed substantially between the surveys (p<0.001). The prevalence of subjects being active on most days of week fell in both genders in the years 2003–2014 (37.4% vs 27.3% in men); 32.7% vs 28.3% in women. None or occasional activity increased from 49.6% to 56.8% in men, while remained stable in women (55.2% vs 54.9%). In both WOBASZ surveys the likelihood of physical inactivity was higher in less educated individuals, smokers and those living in large agglomerations (p<0.01). No significant changes were observed in occupational activity in men between the surveys, while in women percentage of sedentary work increased from 43.4% to % 49.4% (p<0.01). Commuting PA decreased significantly in both genders (p<0.001). About 79.3% of men and 71.3% of women reported no active commuting in the WOBASZ II survey. Conclusions The observed unfavourable changes in PA emphasize the need for novel intervention concepts in order to reverse this direction. Further detailed monitoring of PA patterns in Poland is of particular importance. PMID:27272130

  9. Ten Years of Infrasound Observation in Korea

    NASA Astrophysics Data System (ADS)

    Lee, Hee-Il; Che, Il-Young; Kim, Tae Sung

    2010-05-01

    Over the ten years after the installation of our first seismo-acoustic array station (CHNAR) in September 1999, Korea Institute of Geoscience and Mineral Resources (KIGAM) has been continuously observing infrasound with an infrasound array network, named KIN (Korean Infrasound Network) in Korea. This network consists of seven seismo-acoustic arrays (BRDAR, KMPAR, CHNAR, YAGAR, KSGAR, ULDAR and TJIAR). The aperture size of the smallest array (KMPAR and TJIAR) is about 300m and the largest is about 1.4km. The number of acoustic gauges are between 4 (TJIAR) and 18 (YAGAR), and 1 or 5 seismometers are collocated at the center of the acoustic array. All seismic and infrasonic signals of the arrays are digitized at 40 samples/sec and transmitted to KIGAM in real time. Many interesting infrasound signals associated with different kind of anthropogenic source as well as natural one are detected by KIN. Ten years of seismo-acoustic data are analyzed by using PMCC program, and identified more than five thousand of infrasonic events and catalogued in our infrasound database. This database is used to study characteristics of seasonally dependent propagation of the infrasound wave in local scale, as well as to better understand how atmospheric condition affects the detection ratio at a specific station throughout the year. It also played a valuable role in discriminating the anthropogenic events such as the second nuclear test on 25 May 2009 in North Korea, from natural earthquakes, which is important in estimating the seismicity in Korea.

  10. Women in Astronomy II: Ten Years After

    NASA Technical Reports Server (NTRS)

    Sargent, Wallace

    2004-01-01

    The meeting "Women in Astronomy II: Ten Years After" took place at the California Institute of Technology in Pasadena, CA June 27-28, 2003. The meeting was sponsored by the Committee on the Status of Women of the American Astronomical Society and was attended by about 155 participants. The purpose of the meeting was: "To review the current status of women in astronomy, understand their work environment, assess development since the 1992 Baltimore conference, and recommend future actions that will improve the environment for all astronomers." A description of the meeting and its background can be found at http://www.aas.org/%7Ecswa/WIA2003.html. The proceedings are being edited by Profs. Meg Urry (Yale University) and Ran Bagenal (University of Colorado). The principal outcome of WIAII was a series of recommendations, "The Pasadena Recommendations", which have been approved by the AAS Council and which can be found at http://www.aas.org/%7Ecswa/.

  11. Ten Years of ENA Imaging from Cassini

    NASA Astrophysics Data System (ADS)

    Brandt, Pontus; Mitchell, Donald; Westlake, Joseph; Carbary, James; Paranicas, Christopher; Mauk, Barry; Krimigis, Stamatios

    2014-05-01

    In this presentation we will provide a detailed review of the science highlights of the ENA observations obtained by The Ion Neutral Camera (INCA) on board Cassini. Since the launch of Cassini, INCA has unveiled an invisible world of hot plasma and neutral gas of the two biggest objects of our solar system: the giant magnetosphere of Jupiter and Saturn. Although more than ten years ago, INCA captured the first ENA images of the Jovian system revealing magnetospheric dynamics and an asymmetric Europa neutral gas torus. Approaching Saturn, INCA observed variability of Saturn's magnetospheric activity in response to changes in solar wind dynamic pressure, which was contrary to expectations and current theories. In orbit around Saturn, INCA continued the surprises including the first imaging and global characterization of Titan's exosphere extended out to its gravitational Hill sphere; recurring injections correlating with periodic Saturn Kilometric Radiation (SKR) bursts and magnetic field perturbations; and the discovery of energetic ionospheric outflow. Perhaps most significant, and the focal point of this presentation, is INCA's contribution to the understanding of global magnetospheric particle acceleration and transport, where the combination between ENA imaging and in-situ measurements have demonstrated that transport and acceleration of plasma is likely to occur in a two-step process. First, large-scale injections in the post-midnight sector accelerate and transport plasma in to about 12 RS up to energies of several hundreds of keV. Second, centrifugal interchange acts on the plasma inside of this region and provides further heating and transport in to about 6RS. We discuss this finding in the context of the two fundamental types of injections (or ENA intensifications) that INCA has revealed during its ten years of imaging. The first type is large-scale injections appearing beyond 12 RS in the post-midnight sector that have in many cases had an inward component

  12. Ten years of judicial gatekeeping under Daubert.

    PubMed

    Cecil, Joe S

    2005-01-01

    In the ten years since Daubert v Merrell Dow Pharmaceuticals, Inc, the standards for admissibility at trial of expert testimony in general and scientific evidence in particular have become more demanding. Reviews of recent cases and empirical studies of federal judges' and attorneys' practices indicate that judges are more likely to consider the admissibility of expert evidence prior to trial, to inquire more deeply into the reasoning and methodology that supports the expert opinions, and to limit or exclude such evidence from presentation at trial. Studies of published cases confirm this finding. Recent cases consider more difficult questions arising from the differing methodologies used in various areas of science. The current legal framework that assesses admissibility in terms of professional practice outside the courtroom is poorly suited to cases that require expertise across a wide range of specialties and force judges to choose from among different scientific methodologies. Future research should focus on the pretrial screening of expert testimony and interactions between the attorneys and experts in shaping that testimony.

  13. Ten years of Lusi: A review

    NASA Astrophysics Data System (ADS)

    Miller, Stephen A.

    2016-04-01

    The Lusi mud eruption has continued uninterrupted for ten years, settling into its current steady-state as a quasi-periodic geyser system. Many past, current, and future studies aim to quantify this system, which increasing evidence suggests is a new-born, tectonic scale hydrothermal system linked to the nearby volcano complex. The debate about whether the triggering of Lusi was a natural event of rather caused by drilling continues, but evidence mounts from the behavior of this system that an anthropogenic cause is highly unlikely. Understanding this system is very important because of its social and economic impact on the surrounding communities, and whether it poses future geohazards in the region from future eruptions. A large effort of infrastructures and constant maintenance activity has been and is being conducted inside the 7km2 mud flooded area. This region is framed by a tall embankment that contains the erupted mud and protects the surrounding settlements. This system is also very important for understanding at a larger scale volcanic hydrothermal systems, and to determine whether this new geothermal resource might be exploited. A large effort is underway from an EU-grant supporting the Lusi-Lab project (CEED, University of Oslo) and an SNF grant supporting the University of Neuchatel to study this system from geochemical, geophysical, and modeling perspectives. This review talk summarizes what is known, what is still unclear, and will revisit the behavior of Lusi since its inception.

  14. Lessons learned from ten years of distance learning outreach*

    PubMed Central

    Locatis, Craig; Gaines, Cynthia; Liu, Wei-Li; Gill, Michael; Ackerman, Michael

    2015-01-01

    Objective: The study tested the efficacy of providing distance learning with real-time videoconferencing to broaden high school student knowledge of health careers. Methods: A pilot program was tried out and extended over ten years to include other schools in four different time zones and the National Library of Medicine. Survey results, site visits, and continued school participation were used as effectiveness indicators. Student ratings, site visits, and ongoing discussions were used to evaluate critical factors in the program. Results: Nine program factors contributed to success. Conclusions: Synchronous communication can be effective for outreach to special populations given appropriate infrastructure, technology, program design, and implementation. PMID:25918486

  15. Redefining Assessment? The First Ten Years of Assessment in Education

    ERIC Educational Resources Information Center

    Broadfoot, Patricia; Black, Paul

    2004-01-01

    The completion of the first ten years of this journal is an occasion for review and reflection. The main issues that have been addressed over the ten years are summarized in four main sections: Purposes, International Trends, Quality Concerns and Assessment for Learning. Each of these illustrates the underlying significance of the themes of…

  16. The Chernobyl accident ten years later

    SciTech Connect

    Squires, D.J.

    1996-12-31

    On April 26, 1986 at 1:23 AM a fire and explosion occurred at the fourth unit of the Chernobyl Nuclear Power Plant Complex, located in the Ukraine, that resulted in the destruction of the reactor core and most of the building in which it was housed. Several environmental impacts resulting from the accident will be discussed in this paper, which will include the effects on plant and wild life, radioactive waste generated and stored or disposed of, effects of evacuations relating to residents within the subsequently established 10km and 30km control zones, impacts of the emergency containment structure (sarcophagus), and potential effects on world opinion and future development of nuclear power. As an immediate result of the fire, 31 people died (2 from the fire & smoke, and 29 from excessive radiation); 237 cases of acute radiation sickness occurred; the total fatalities based upon induced chronic diseases as a result of the accident is unknown: more than 100,000 people were evacuated from within the subsequently established 30 km control zone; in excess of 50 million curies of radionuclides that included finely dispersed nuclear fuel, fragments of graphite, concrete and other building materials were released from the reactor into the environment; an estimated one million cubic meters of radioactive waste were generated (LLW, ILW, HLW); more than 5000 tons of materials (sand, boron, dolomite, cement, and lead) were used to put the fire out by helicopter; shutdown of the adjacent power plants were performed; and other environmental impacts occurred. The Chernobyl Nuclear Power Plant Unit No 4 is an RBMK-1000. It initiated operations in 1983, it was a 1000 MWe with a power output of 3200 MW(th), the reactor core contained 190 MT of fuel, with 1659 assemblies (plus 211 control rods), the average burnup rate was 10.3 MWd/kg, and the reactor operated on a continuous basis with maintenance and fuel reload performed during operations.

  17. Minimally invasive thyroidectomy: a ten years experience

    PubMed Central

    Viani, Lorenzo; Montana, Chiara Montana; Cozzani, Federico; Sianesi, Mario

    2016-01-01

    Background The conventional thyroidectomy is the most frequent surgical procedure for thyroidal surgical disease. From several years were introduced minimally invasive approaches to thyroid surgery. These new procedures improved the incidence of postoperative pain, cosmetic results, patient’s quality of life, postoperative morbidity. The mini invasive video-assisted thyroidectomy (MIVAT) is a minimally invasive procedure that uses a minicervicotomy to treat thyroidal diseases. Methods We present our experience on 497 consecutively treated patients with MIVAT technique. We analyzed the mean age, sex, mean operative time, rate of bleeding, hypocalcemia, transitory and definitive nerve palsy (6 months after the procedure), postoperative pain scale from 0 to 10 at 1 hour and 24 hours after surgery, mean hospital stay. Results The indications to treat were related to preoperative diagnosis: 182 THYR 6, 184 THYR 3–4, 27 plummer, 24 basedow, 28 toxic goiter, 52 goiter. On 497 cases we have reported 1 case of bleeding (0,2%), 12 (2,4%) cases of transitory nerve palsy and 4 (0,8%) definitive nerve palsy. The rate of serologic hypocalcemia was 24.9% (124 cases) and clinical in 7.2% (36 cases); 1 case of hypoparathyroidism (0.2%). Conclusions The MIVAT is a safe approach to surgical thyroid disease, the cost are similar to CT as the adverse events. The minicervicotomy is really a minimally invasive tissue dissection. PMID:27294036

  18. EXTREMITY SARCOMA SURGERY IN YOUNGER CHILDREN: TEN YEARS OF PATIENTS TEN YEARS AND UNDER

    PubMed Central

    Israelsen, Ryan B; Ilium, Benjamin E; Crabtree, Susie; Randall, R Lor; Jones, Kevin B

    2011-01-01

    Sarcoma surgeons face unique challenges in younger patients with significant skeletal growth remaining. The heightened concerns regarding radiation in the very young and the drastic changes expected in the lengths and cross-sectional areas of bones affect the decision-making for both soft-tissue and bone sarcomas in this population. Nonetheless, there is sparse literature focused on sarcoma surgery in this age group. The records of one tertiary regional sarcoma treatment program were reviewed to identify all patients ten years old or younger at the time of local control surgery for limb or limb-girdle sarcomas. Demographic information, diagnosis, surgery performed, complications, and general outcomes were gleaned from the medical records. 43 patients were identified, including 15 with osteosarcomas, 11 Ewing’s sarcoma family tumors, five rhabdomyosarcomas, and two synovial sarcomas, among others. Location of tumors varied widely, but demonstrated a predilection for the upper extremity more than is typical in adolescents with the same tumor types. Survival was favorable overall, with only five patients dying from disease. Most patients continued to function well at latest follow-up, but 16 experienced additional surgical interventions following the index procedure. Sarcoma surgery in the younger growing child presents challenges for the surgeon, patient, and parents, but is usually successful in the long-term. PMID:22096434

  19. Ten years of snakebites in Iran.

    PubMed

    Dehghani, Rouhullah; Fathi, Behrooz; Shahi, Morteza Panjeh; Jazayeri, Mehrdad

    2014-11-01

    Many species of venomous snakes are found in Iran. The most medically important species which are responsible for the most snakebite incidents in Iran belong to the Viperidae family, including Vipera lebetina, Echis carinatus, Pseudocerastes persicus, Vipera albicornuta and the Elapidae family, especially Naja naja oxiana. At least one kind of venomous snake is found in each of the 31 provinces, and many provinces have more than one venomous species. As a result, snakebite is a considerable health hazard in Iran, especially in the rural area of south and south-west of Iran. A retrospective, descriptive study of snakebite in Iran during 2002-2011 was carried out in order based on data collected from medical records of bite victims admitted to hospitals and health centers. From 2002 to 2011, 53,787 cases of snake bites were reported by medical centers in Iran. The annual incidence of snake bites in 100,000 of population varied from 4.5 to 9.1 during this decade and the number of recorded deaths were about 67 cases. The highest rate of snakebite was found in provinces of south and southwest of Iran. We suggest that people, especially in the rural areas, need to be trained and educated about venomous snakes, their hazards, prevention of bite and the importance of early hospital referral and treatment of victims. Also adequate antivenins as the main life saving medicine should be made available based on the recorded numbers of victims in each area of the country.

  20. Planning the global family. Ten years on.

    PubMed

    Singh, J S

    1984-06-01

    Estimates from the UN indicate that world population should finally stabilize at 10.2 billion people, growth stopping around 2100 when the number dying will finally match the number being born. The debate at the August 1984 UN sponsored gathering in Mexico City, the International Conference on Population, promises to be more practical than rhetorical than at the 1974 conference. In 1974 there were 2 opposed views of population growth: population soaring and the world's resources buckling under the strain with family planning viewed as the most effective remedy; and large families were a result of poverty rather than a cause of it and by eliminating poverty one would eliminate the need for large families. Experience gained over the last decade has moved the 2 sides together. Supporters of family planning as the only solution to world poverty found it to be of limited use unless it was related to activities on other issues such as delivery of basic health services, literacy, reductions in child and maternal mortality, and the status of women. Those who argued that development was the best contraceptive found that giving parents financial security helped to pave the way to smaller families but was not sufficient on its own. Vigorous family planning campaigns were still needed to make information and services acceptable and available to those who did decide to limit their families. The comprehensive World Fertility Survey (WFS) provides evidence from 43 developing countries to support this conclusion. The WFS interviewed thousands of women who said that they did not want any more children and found that less than half of these were actually using any form of contraception. Developing countries are now taking an active stance on population. 2/3 of the developing countries, containing 80% of the total population, expressed concerns about high fertility. The Asian governments have worked out their population policies in greatest detail, and most have set precise targets

  1. In favour of the definition "adolescents with idiopathic scoliosis": juvenile and adolescent idiopathic scoliosis braced after ten years of age, do not show different end results. SOSORT award winner 2014

    PubMed Central

    2014-01-01

    Background The most important factor discriminating juvenile (JIS) from adolescent idiopathic scoliosis (AIS) is the risk of deformity progression. Brace treatment can change natural history, even when risk of progression is high. The aim of this study was to compare the end of growth results of JIS subjects, treated after 10 years of age, with final results of AIS. Methods Design: prospective observational controlled cohort study nested in a prospective database. Setting: outpatient tertiary referral clinic specialized in conservative treatment of spinal deformities. Inclusion criteria: idiopathic scoliosis; European Risser 0–2; 25 degrees to 45 degrees Cobb; start treatment age: 10 years or more, never treated before. Exclusion criteria: secondary scoliosis, neurological etiology, prior treatment for scoliosis (brace or surgery). Groups: 27 patients met the inclusion criteria for the AJIS, (Juvenile Idiopathic Scoliosis treated in adolescence), demonstrated by an x-ray before 10 year of age, and treatment start after 10 years of age. AIS group included 45 adolescents with a diagnostic x-ray made after the threshold of age 10 years. Results at the end of growth were analysed; the threshold of 5 Cobb degree to define worsened, improved and stabilized curves was considered. Statistics: Mean and SD were used for descriptive statistics of clinical and radiographic changes. Relative Risk of failure (RR), Chi-square and T-test of all data was calculated to find differences among the two groups. 95% Confidence Interval (CI) , and of radiographic changes have been calculated. Results We did not find any Cobb angle significant differences among groups at baseline and at the end of treatment. The only difference was in the number of patients progressed above 45 degrees, found in the JIS group. The RR of progression of AJIS was, 1.35 (IC95% 0.57-3.17) versus AIS, and it wasn't statistically significant in the AJIS group, in respect to AIS group (p = 0.5338). Conclusion

  2. Trends in paediatric rheumatology referral times and disease activity indices over a ten-year period among children and young people with Juvenile Idiopathic Arthritis: results from the childhood arthritis prospective Study

    PubMed Central

    McErlane, Flora; Foster, Helen E.; Carrasco, Roberto; Baildam, Eileen M.; Chieng, S. E. Alice; Davidson, Joyce E.; Ioannou, Yiannis; Wedderburn, Lucy R.; Thomson, Wendy

    2016-01-01

    Objectives. The medical management of JIA has advanced significantly over the past 10 years. It is not known whether these changes have impacted on outcomes. The aim of this analysis was to identify and describe trends in referral times, treatment times and 1-year outcomes over a 10-year period among children with JIA enrolled in the Childhood Arthritis Prospective Study. Methods. The Childhood Arthritis Prospective Study is a prospective inception cohort of children with new-onset inflammatory arthritis. Analysis included all children recruited in 2001–11 with at least 1 year of follow-up, divided into four groups by year of diagnosis. Median referral time, baseline disease pattern (oligoarticular, polyarticular or systemic onset) and time to first definitive treatment were compared between groups. Where possible, clinical juvenile arthritis disease activity score (cJADAS) cut-offs were applied at 1 year. Results. One thousand and sixty-six children were included in the analysis. The median time from symptom onset and referral to first paediatric rheumatology appointment (22.7–24.7 and 3.4–4.7 weeks, respectively) did not vary significantly (∼20% seen within 10 weeks of onset and ∼50% within 4 weeks of referral). For oligoarticular and polyarticular disease, 33.8–47 and 25.4–34.9%, respectively, achieved inactive disease by 1 year, with ∼30% in high disease activity at 1 year. A positive trend towards earlier definitive treatment reached significance in oligoarticular and polyarticular pattern disease. Conclusion. Children with new-onset JIA have a persistent delay in access to paediatric rheumatology care, with one-third in high disease activity at 1 year and no significant improvement over the past 10 years. Contributing factors may include service pressures and poor awareness. Further research is necessary to gain a better understanding and improve important clinical outcomes. PMID:27016664

  3. Ten years in the library: new data confirm paleontological patterns

    NASA Technical Reports Server (NTRS)

    Sepkoski, J. J. Jr; Sepkoski JJ, J. r. (Principal Investigator)

    1993-01-01

    A comparison is made between compilations of times of origination and extinction of fossil marine animal families published in 1982 and 1992. As a result of ten years of library research, half of the information in the compendia has changed: families have been added and deleted, low-resolution stratigraphic data been improved, and intervals of origination and extinction have been altered. Despite these changes, apparent macroevolutionary patterns for the entire marine fauna have remained constant. Diversity curves compiled from the two data bases are very similar, with a goodness-of-fit of 99%; the principal difference is that the 1992 curve averages 13% higher than the older curve. Both numbers and percentages of origination and extinction also match well, with fits ranging from 83% to 95%. All major events of radiation and extinction are identical. Therefore, errors in large paleontological data bases and arbitrariness of included taxa are not necessarily impediments to the analysis of pattern in the fossil record, so long as the data are sufficiently numerous.

  4. Ten Years after Columbine: The Tragedy of Youth Deepens

    ERIC Educational Resources Information Center

    Giroux, Henry A.

    2009-01-01

    For young people it just gets worse. Ten years after the Columbine tragedy, the debate over school safety has clearly shown that educators, parents, politicians, and the mainstream media have created the conditions in which young people have increasingly become the victims of adult mistreatment, indifference, neglect, even violence. The tragic…

  5. A ten year review of performance of photovoltaic systems

    SciTech Connect

    Rosenthal, A.L.; Durand, S.J.; Thomas, M.G.

    1993-06-01

    This paper presents data compiled by the Photovoltaic Design Assistance Center at Sandia National Laboratories from more than eighty field tests performed at over thirty-five photovoltaic systems in the United States during the last ten years. The recorded performance histories, failure rates, and degradation of post-Block IV modules and balance-of-system (BOS) components are described in detail.

  6. The First Ten Years. National Sea Grant College Program.

    ERIC Educational Resources Information Center

    Hull, E. W. Seabrook

    Detailed are the first ten years of the Sea Grant Program through 1976. The review is divided into three parts. Part I, Sea Grant Origin and Process, traces the historical development of the program and cites the program's philosophy. Part II, Sea Grant in Action, discusses marine resource development, marine technology, research and development,…

  7. Ten-year longitudinal clinical evaluation of a visible light cured posterior composite resin.

    PubMed

    Shimizu, T; Kitano, T; Inoue, M; Narikawa, K; Fujii, B

    1995-12-01

    Using modified USPHS criteria, we evaluated annually for ten years 91 cases restored with visible light cured posterior composite resin LFP (Base resin: UDMA; filler: micro crushed type, alumino-silicate, barium glass and silica, 85 wt%, 74 vol%). The 91 cases restored with LFP decreased to 68 in ten years. Of the 23 cases that were lost, one resulted from a pulpal reaction immediately following restoration, four were extracted owing to periodontal disease or extrusion of third molars, two became abutments owing to loss of an adjacent tooth, eight had recurrent caries, and eight were lost owing to caries on a surface having no relationship to the composite resin restoration. Because we observed comparatively little wear, good marginal adaptability, and no discoloration, we concluded that the ten-year clinical success of LFP was on the whole very good, and that this resin has adequate clinical merit as a restorative material for posterior teeth when restricted to restorations covering comparatively small areas.

  8. Ten years of catalyst recycling: A step to the future

    SciTech Connect

    Case, A.; Garretson, G.; Wiewiorowski, E.

    1995-12-31

    The Port Nickel facility in Braithwaite, Louisiana, is known for pioneering hydrometallurgical processes for the separation and recovery of nickel, cobalt and copper. Ten years ago, in 1985, a new CRI-MET process for the recovery of molybdenum, vanadium, nickel, cobalt and alumina from spent catalysts was developed and implemented. Spent catalysts from the petroleum industry constitute the majority of feed. These are not only a valuable source of metals, but due to EPA regulations are frequently classified as hazardous under RCRA. Molybdenum and vanadium are selectively leached in an oxidative hydrothermal step. Alumina is then extracted in a Caustic digestive leach. The unique technology produces four primary commercial products: molybdenum trioxide, vanadium oxide, aluminum trihydrate and nickel-cobalt concentrate. This paper discusses the process, modifications during ten years of operation, and the relationship of these modifications to the future of the catalyst recycling business.

  9. Reflections on Ten Years of Network Time Service

    DTIC Science & Technology

    2005-01-01

    36th Annual Precise Time and Time Interval (PTTI) Meeting 1 REFLECTIONS ON TEN YEARS OF NETWORK TIME SERVICE Richard...Schmidt Time Service Department U.S. Naval Observatory Washington, DC 20392-5420, USA E-mail: res@tuttle.usno.navy.mil Abstract The year...2004 marks the 10th anniversary since the start of U.S. Naval Observatory (USNO) time dissemination on the Internet using the Network Time Protocol

  10. Educational Virtual Environments: A Ten-Year Review of Empirical Research (1999-2009)

    ERIC Educational Resources Information Center

    Mikropoulos, Tassos A.; Natsis, Antonis

    2011-01-01

    This study is a ten-year critical review of empirical research on the educational applications of Virtual Reality (VR). Results show that although the majority of the 53 reviewed articles refer to science and mathematics, researchers from social sciences also seem to appreciate the educational value of VR and incorporate their learning goals in…

  11. Indirect composite restorations luted with two different procedures: A ten years follow up clinical trial

    PubMed Central

    Preti, Alessandro; Vano, Michele; Derchi, Giacomo; Mangani, Francesco; Cerutti, Antonio

    2015-01-01

    Objectives: The aim of this clinical trial was to evaluate posterior indirect composite resin restoration ten years after placement luted with two different procedures. Study Design: In 23 patients 22 inlays/onlays (Group A) were luted using a dual-cured resin composite cement and 26 inlays/onlays (Group B) were luted using a light cured resin composite for a total of 48 Class I and Class II indirect composite resin inlays and onlays. The restorations were evaluated at 2 time points: 1) one week after placement (baseline evaluation) and 2) ten years after placement using the modified USPHS criteria. The Mann-Whitney and the Wilcoxon tests were used to examine the difference between the results of the baseline and 10 years evaluation for each criteria. Results: Numerical but not statistically significant differences were noted on any of the recorded clinical parameters (p>0.05) between the inlay/onlays of Group A and Group B. 91% and 94 % of Group A and B respectively were rated as clinically acceptable in all the evaluated criteria ten years after clinical function. Conclusions: Within the limits of the study the results showed after ten years of function a comparable clinical performance of indirect composite resin inlays/onlays placed with a light cure or dual cure luting procedures. Key words:Light curing composite, dual curing composite, indirect composite restoration, inlays/onlays, clinical trial. PMID:25810842

  12. Ural-Tweed Bighorn Sheep Wildlife Mitigation Project, 1984-1990 Final Report.

    SciTech Connect

    Young, Lewis R.; Yde, Chris A.

    1990-06-01

    The results of habitat improvement project activities accomplished under contract No.84-38 for bighorn sheep mitigation along Koocanusa Reservoir from September 1, 1984, through June 30, 1990, are reported here. Habitat treatments were applied to ten areas and covered 1100 acres. Treatments used were prescribed fire, slashing combined with prescribed fire, and fertilization. Several variations in season or intensity were used within the slashing and prescribed fire treatments. This project was coordinated with and complemented concurrent Kootenai National Forest habitat improvement activities.

  13. Ten years of progress in the Superfund Program

    SciTech Connect

    Clay, D.R. )

    1991-02-01

    Superfund celebrated its tenth anniversary in December 1990. The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) - popularly known as Superfund - was passed into law in December 1980 in the wake of such incidents as Love Canal and the Valley of the Drums. The program was designed to clean up uncontrolled hazardous waste sites and, during the past ten years, thousands of actions have been taken to protect human health and the environment from the hazards posed by those sites. EPA believes that goal is best met by its strategy: make sites safer - control immediate threats; enforce aggressively; make sites cleaner - worst problems at worst sites first; bring new technology to bear on the problem.

  14. Ten-year evaluation of conservative and surgical treatment of gingival recession. A case series study.

    PubMed

    Jorgić-Srdjak, K; Bosnjak, A; Plancak, D; Maricević, T

    2000-12-01

    In the last years the treatment of non-inflammatory periodontal diseases has greatly changed. Apico-coronal dimension of gingival tissue is not considered to be of utmost importance, but significance of tissue thickness over each tooth is stressed. Purpose of this study was to show results of conservative and surgical treatment of gingival recession. Sample consisted of two groups of subjects, which have been treated in one of stated ways during ten years. The data was obtained on the beginning and after ten years of recall. Both groups showed increased dimension of keratinized gingiva during observed time with decrease of gingival recession, plaque- and gingival index. It is considered that treatment should start with conservative measures with necessary motivation of the patients. If it does not show improvement, one should consider best surgical method available for each patient. Clinical results show success in both groups, meaning that treatment was properly decided on.

  15. Holistic System of Care: a ten-year perspective.

    PubMed

    Nebelkopf, Ethan; Wright, Serena

    2011-01-01

    The Holistic System of Care for Native Americans in an Urban Environment is a community-focused intervention that provides behavioral health care, promotes health, and prevents disease. This approach is based on a community strategic planning process that honored Native American culture and relationships. Substance abuse, mental illness, homelessness, poverty, crime, physical illness, and violence are symptoms of historical trauma, family dysfunction, and spiritual imbalance. The holistic model links treatment, prevention, and recovery. The link between prevention and treatment is early intervention. Peer support is the link between treatment and recovery. Recovering individuals serve as role models linking recovery to prevention. Culture and spirituality build a strong and resilient foundation for recovery. This article documents the effectiveness of the holistic model over a ten-year period that it has been implemented at the Family & Child Guidance Clinic of the Native American Health Center in the San Francisco Bay Area. The holistic model has produced statistically significant reductions in substance abuse among adult Native American women, men, reentry, and homeless populations; reductions in substance abuse among Native American adolescents; reductions in HIV/AIDS high-risk behavior among Native American men, women, and adolescents; and decreases in acting out behavior among Native American severely emotionally disturbed children.

  16. A ten year Moment Tensor database for Western Greece

    NASA Astrophysics Data System (ADS)

    Serpetsidaki, Anna; Sokos, Efthimios; Tselentis, G.-Akis

    2016-10-01

    Moment Tensors (MTs) provide important information for seismotectonic, stress distribution and source studies. It is also important as a real time or near real time information in shakemaps, tsunami warning, and stress transfer. Therefore a reliable and rapid MT computation is a routine task for modern seismic networks with broadband sensors and real-time digital telemetry. In this paper we present the database of Moment Tensor solutions computed during the last ten years in Western Greece by the University of Patras, Seismological Laboratory (UPSL). The data from UPSL broad band network were used together with the ISOLA Moment Tensor inversion package for routine MT calculation. The procedures followed and the comparison of UPSL derived solutions with the ones provided by other agencies for Western Greece region are presented as well. The Moment Tensor database includes solutions for events in the magnitude range 2.8-6.8 and provides a unique insight into the faulting characteristics of Western Greece. Moreover it paves the way for detailed studies of stress tensor and stress transfer. The weak events' Moment Tensor included in UPSL's database are important for the comprehension of local seismotectonics and reveal the role of minor faults, which may be critical in seismic hazard estimation.

  17. A University Department of Family Medicine After Ten Years

    PubMed Central

    Geyman, John P.; Phillips, Theodore J.

    1982-01-01

    The Department of Family Medicine at the University of Washington was started ten years ago after a major curriculum change in the medical school placed new emphasis on education and training of family physicians for the surrounding region in Washington, Alaska, Montana and Idaho (WAMI). This department has organized active programs in patient care, teaching and research at the university base and in a number of affiliated community sites throughout the region. The department is well accepted within the mission of the medical school. Almost a third of graduating medical students choose postgraduate training in family practice. Almost 90 percent of the graduates of the ten programs within the department's network of family practice residencies are established in active family practices, with more than two thirds settling in the WAMI region. Follow-up studies show that these graduates feel well prepared for their practices; are providing a broad range of services in rural, suburban and urban settings; are typically involved in partnership or group practice; and are generally well satisfied with their personal and professional lives. PMID:7064482

  18. Ten Years of Real-Time Earthquake Loss Alerts

    NASA Astrophysics Data System (ADS)

    Wyss, M.

    2013-12-01

    The priorities of the most important parameters of an earthquake disaster are: Number of fatalities, number of injured, mean damage as a function of settlement, expected intensity of shaking at critical facilities. The requirements to calculate these parameters in real time are: 1) Availability of reliable earthquake source parameters within minutes. 2) Capability of calculating expected intensities of strong ground shaking. 3) Data sets on population distribution and conditions of building stock as a function of settlements. 4) Data on locations of critical facilities. 5) Verified methods of calculating damage and losses. 6) Personnel available on a 24/7 basis to perform and review these calculations. There are three services available that distribute information about the likely consequences of earthquakes within about half an hour of the event. Two of these calculate losses, one gives only general information. Although, much progress has been made during the last ten years improving the data sets and the calculating methods, much remains to be done. The data sets are only first order approximations and the methods bare refinement. Nevertheless, the quantitative loss estimates after damaging earthquakes in real time are generally correct in the sense that they allow distinguishing disastrous from inconsequential events.

  19. Frequency of serial sexual homicide victimization in Virginia for a ten-year period.

    PubMed

    McNamara, James J; Morton, Robert J

    2004-05-01

    The frequency of serial sexual murder has been widely discussed, and estimates of the number of victims in the United States range from 500 to 6000 per year. This study attempted to quantify the number of serial sexual murder victims in Virginia for a ten-year period. Multiple sources of data were utilized, including Federal Bureau of Investigation (FBI) case files, FBI's Violent Criminal Apprehension Program (ViCAP) reports, Virginia State Police ViCAP reports, Virginia Homicide Investigators Association, and the Virginia Division of Forensic Science DNA database, to effectively cull out all the known serial sexual murder victims for the given time period. Review of these records revealed a total of 28 victims of serial sexual murder, compared with a total of 5183 murder victims for the same ten-year period. The frequency of serial sexual victimization was 0.5% of all homicides for the given period. These results highlight the unusual frequency of serial sexual murder.

  20. The State of the Carbon Cycle: Ten Years On

    NASA Astrophysics Data System (ADS)

    King, A. W.; Dilling, L.; Fairman, D. M.; Houghton, R. A.; Marland, G.; Rose, A.; Wilbanks, T. J.; Zimmerman, G.

    2015-12-01

    It has been nearly ten years since the First State of the Carbon Cycle Report (SOCCR-1) was published in 2007. Much has changed in the intervening years, but much has remained the same. In anticipation of a Second State of the Carbon Cycle Report (SOCCR-2), we, the members of the SOCCR-1 Coordinating Team, felt that a perspective from the first SOCCR and reflection on changes in the state of carbon cycle science and policy in the intervening years would be appropriate. The purpose of SOCCR-1 was to provide "…a synthesis and integration of the current knowledge of the North American carbon budget and its context within the global carbon cycle [i]n a format useful to decision makers." Being "useful to decision makers" was a guiding theme with three stakeholder workshops an integral part of the process. Drafting and revision of SOCCR-1 took place between 2005 and early 2007; the report's carbon budget was for circa 2003. In 2003, North America's fossil-fuel CO2 emissions were approximately 27% of global emissions. Nearly 85% of North American emissions were from the US, still at that time the world's largest emitter of fossil-fuel CO2. China's annual CO2 emissions exceeded those of the US for the first time while SOCCR-1 was being written. Today global CO2 emissions are dominated by emissions from China (28% in 2013), with US emissions only 14% of global emissions. Emissions from the US and North America have actually declined by approximately 10% since 2003 while emissions from China have doubled. Based on inventories of terrestrial carbon stocks, SOCCR-1 estimated that circa 2003 North American vegetation removed and stored a net 500 Mt C y-1 (±50%) from the atmosphere. A more recent synthesis incorporating additional estimates from atmospheric inversions and terrestrial biosphere modeling estimated the North American land sink for the decade of 2000-2009 at 350-470 Mt C y-1, with a slightly greater uncertainty due to the wider range of estimates from the

  1. The Nottingham Prognostic Index: five- and ten-year data for all-cause Survival within a Screened Population

    PubMed Central

    Evans, J; Brook, D; Kenkre, J; Jarvis, P; Gower-Thomas, K

    2015-01-01

    Introduction The Nottingham Prognostic Index (NPI) is an established prognostication tool in the management of breast cancers (BCs). Latest ten-year survival data have demonstrated an improved outlook for each NPI category and the latest UK five- and ten-year survival from BC has been reported to be 85% and 77%, respectively. We compared survival of each NPI category for BCs diagnosed within the national breast screening service in Wales (Breast Test Wales (BTW)) to the latest data, and reviewed its validity in unselected cases within a screened population. Methods All women screened between 1998 and 2001 within BTW were included. The NPI score for each cancer was calculated using the size, nodal status, and grade of the primary tumour. Survival data (all-cause) were calculated after ten years of follow-up. Results In the three-year screening period, 199,082 women were screened. A total of 1,712 cancers were diagnosed, and 1,546 had data available for calculating the NPI. Overall five-year and ten-year survival was 94% and 82%, respectively. Conclusions Overall five-year and ten-year survival (all-cause) has improved even when compared with UK data for BC-specific survival. We found that the NPI remains valid for BC treatment, and that our data provide a reference for updating the all-cause survival of women diagnosed with BCs within a screened population. PMID:25723691

  2. Ten Years of Tamoxifen Reduces Breast Cancer Recurrences, Improves Survival

    Cancer.gov

    Taking adjuvant tamoxifen for 10 years after primary treatment leads to a greater reduction in breast cancer recurrences and deaths than taking the drug for only 5 years, according to the results of a large international clinical trial.

  3. Ten-Year Study of a Wilson's Disease Dysarthric.

    ERIC Educational Resources Information Center

    Day, Linda Susan; Parnell, Martha M.

    1987-01-01

    The 10-year longitudinal case study describes the history, speech therapy program, and treatment results for an adult male with Wilson's disease, a genetically based metabolic progressive neurological disorder which includes severe speech problems. (DB)

  4. [D.K. Beliaev's evolutionary concept--ten years later].

    PubMed

    Trut, L N

    1997-08-01

    D.K. Belyaev's evolutionary concept is considered in terms of (1) experimental results obtained during studies on domestication mainly in recent years and (2) modern views on evolution under extreme conditions and the role of the hierarchic system of regulation of genetic expression in evolution. Changes in neuroendocrine regulation in the course of long-term domestication are characterized, and the morphogenetic role of hormones and neurotransmitters is discussed. The effects of selection on the rate of some developmental processes and the importance of the resultant heterochronias for the morphogenetic consequences of selection for behavior are described.

  5. Scientific achievements from ten years of lunar laser ranging

    NASA Technical Reports Server (NTRS)

    Mulholland, J. D.

    1980-01-01

    In the 10 years since lunar laser ranging became a reality the need to analyze the observations has motivated improvements in several aspects of the mathematical model of earth-moon dynamics. Application of the data to improved estimates of the physical parameters of the earth-moon system has yielded significant astronomical, selenophysical, geophysical, and cosmological results. The scientific impact, both in improved theories and in numerical applications, is surveyed. The underlying physics and major difficulties are discussed, as well as the scientific results.

  6. The Catholic School under Scrutiny: Ten Years of Research in Italy (1998-2008)

    ERIC Educational Resources Information Center

    Malizia, Guglielmo; Cicatelli, Sergio

    2011-01-01

    This book delineates the evolution of the Study Centre for Catholic Schools (CSSC) in its first ten years of existence since its foundation in 1998 by the Italian Bishops' Conference. The volume is divided into three main sections. The first outlines the context and the activity of the CSSC during ten years: the role, the functions, the tasks and…

  7. Computing Trends in Small Liberal Arts Colleges: Ten Years Later.

    ERIC Educational Resources Information Center

    Smith, Peter

    Forty-one small liberal arts colleges were visited during the 1997-98 school year in order to talk to key information technology staff and to see computing facilities. A survey containing 15 factual and 10 open-ended questions was used to gather information. This paper presents findings in the following areas and comparison with results of a…

  8. Ten Years Later: Locating and Interviewing Children of Drug Abusers

    ERIC Educational Resources Information Center

    Haggerty, Kevin P.; Fleming, Charles B.; Catalano, Richard F.; Petrie, Renee S.; Rubin, Ronald J.; Grassley, Mary H.

    2008-01-01

    Longitudinal studies require high follow-up rates in order to maintain statistical power, reduce bias, and enhance the generalizability of results. This study reports on locating and survey completion for a 10-year follow-up of the Focus on Families project, an investigation of 130 families headed by parents who were enrolled in methadone…

  9. National Sea Grant College Program: The First Ten Years.

    ERIC Educational Resources Information Center

    Hull, E. W. Seabrook

    The National Sea Grant College Program sponsors efforts which encompass research applied to current problems, labor force development, and transfer of technology and knowledge to people who need it in a form they can use. Summarized in this report are Sea Grant's history, programs, and results during its first decade (1967-1976). Provided is an…

  10. Ten-year study on acid precipitation nears conclusion

    SciTech Connect

    Olem, H. )

    1990-04-01

    Results from the National Acid Precipitation Assessment Program (NAPAP) are discussed. Final results are contained in 26 state of the science reports. Seven of the reports provide information on acid rain and aquatic ecosystems. They describe the current state of acidic surface waters, watershed processes affecting surface water chemistry, historical evidence for surface water acidification, methods for forecasting future changes, and the response of acidic surface water to liming. Six areas of the country were found to be of special interest: southwest Adirondacks, New England, forested areas of the mid-Atlantic highlands, the Atlantic coastal plain, the northern Florida highlands, parts of northeastern Wisconsin and the Upper Peninsula of Michigan. Environmental effects, mitigation efforts and possible legislation are briefly discussed.

  11. Solar induced terrestrial plant fluorescence derived of ten years of SCIAMACHY data.

    NASA Astrophysics Data System (ADS)

    Vountas, M.; Rozanov, V. V.; Khosravi, N.; Bracher, A.; Burrows, J. P.

    2014-12-01

    Plant fluorescence has a direct link to photosynthetic efficiency. Satelite-based remote sensing has been shown to have the potential to derive it on a global scale- accordingly it became subject of various recently published studies and stimulated an upsurge in this research field. This study presents a novel retrieval method for solar induced terrestrial plant fluorescence (SIF). When used with typical spectrometer data an additive spectral component not induced by fluorescence is often accompanying the actual SIF retrieval and can significantly deteriorate the results. To account for this effect a correction method is combined with the retrieval. The method has been applied to ten years of SCIAMACHY data with promising results. In absence of large area ground based validation data a final judgement of the results presented is not feasible. A direct comparison to data of others was showing promising and in certain regions ambivalent results.

  12. Ten years of experience from interactive ergonomics projects.

    PubMed

    Eklund, J; Karltun, J

    2012-01-01

    This paper highlights experiences from ergonomics projects, applying an interactive research approach. The aim of this paper is to summarise experiences from seven interactive ergonomics projects with the aim to improve ergonomics and organizational performance jointly. Results from these seven projects were analysed with a model for assessing sustainable change, including the factors active ownership, professional management, competent project leadership, and involved participants. All factors were found giving support to impact and sustainability of the change projects. However, the role of the researcher is difficult and demanding.

  13. Endoscopic Repair of CSF Fistulae: A Ten Year Experience

    PubMed Central

    Alexander, Arun; Mathew, John; Varghese, Ajoy Mathew

    2016-01-01

    Introduction Cerebrospinal Fluid (CFF) fistulae are repaired endoscopically with varying degrees of success around the world. Large series are still uncommon, and the results varied primarily because of the different techniques by different surgeons and also because of a variation in the patient profile in each series, for example, many series deal primarily with traumatic CSF leaks where the defects are larger and outcomes poorer. Aim To analyse the surgical outcomes of Endoscopic CSF rhinorrhea closure. Materials and Methods This is a series of 34 cases operated upon primarily by one surgeon in two different centres over a period of 10 years. Results Of the 34 cases, 76% of the patients were women. Among the patients only 20.6% patients had a history of trauma preceding the CSF leak. The most common site of leak was in the fovea ethmoidalis in 19 (55.8%) followed by 10 (29.4%) in the cribriform plate. An overlay technique of placing the multiple layers of fascia and mucosa was used in 26 (76.5%) patients and underlay technique in the remaining. Postoperative lumbar drain was used in all patients. Conclusion Based on the treatment outcome of the 34 patients, it can be concluded that the success rate of a single endoscopic procedure in our experience is 97% and 100% following the second. Endoscopic approach for closure of CSF leak is safe with minimal complications and little morbidity. PMID:27656471

  14. Ten Years in the Making: AUSM-Family

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing

    2001-01-01

    We begin by describing the motivations that gave birth to the original AUSM scheme and then focus on the ingredients that has spurred its growth and acceptance by the world of computational fluid dynamics. As it has played out more in the field, weaknesses have also surfaced. Hence, nutrients and supplements are prescribed to help it grow and stay strong and robust. In this paper, we will describe the saga of efforts owing to researchers who have contributed to building up the AUSM-family for the CFD community. It is hoped that a healthy scheme will contribute to the accurate and robust solution of problems encountered in a wide range of disciplines. We analyze numerical mass fluxes with an emphasis on their capability for accurately capturing shock and contact discontinuities. We will present a new scheme for the pressure flux, along with results for a host of test problems.

  15. [Imatinib in the GIST therapy: ten years later].

    PubMed

    Lopez, M

    2011-01-01

    Gastrointestinal stromal tumors (GIST) are the most common sarcomas of the gastrointestinal tract, known to be resistant to chemotherapy and radiotherapy. The recognition that KIT mutations were present in the majority of patients with GIST led to clinical trials of imatinib in this disease. Indeed, imatinib inhibits KIT kinase activity and represents the best drug for the treatment of unresectable and advanced GIST, achieving a partial response or stable disease in 85-90% of patients with metastatic disease. KIT activation is generally linked to somatic mutations, usually involving exon 11 or 9. Other less often involved genes are PDGFRA or BRAF. The presence and the type of KIT or PDGFRA mutation status are predictive of response to imatinib therapy in patients with advanced or metastatic GIST, as well as prognostic for relapse-free survival (RFS) after surgical resection of primary GIST. Defined risk factors for recurrent disease are mainly based on GIST size, location, and mitotic rate and provide useful guidelines for selecting patients for adjuvant therapy. Neoadjuvant therapy with imatinib has several potential advantages, including tumor downsizing to provide the opportunity for decreasing the morbidity of surgical resection as well as to decrease risk of intraoperative tumor rupture. Based on the results of ACOSOG Z9001 trial, in December 2008, the FDA approved imatinib for postoperative treatment of patients with resected KIT-positive GIST; optimum duration of adjuvant treatment was not stated. Recently, the final results of the SSGXVIII/AIO trial showed that 36 months compared to 12 months of adjuvant imatinib were significantly better in extending RFS and overall survival in patients with operable GIST with a high risk of recurrence (NIH classification). Treatment was generally well tolerated. During the last decade, striking advances have been made in the understanding, characterization, and treatment of GIST, which have emerged as a leading paradigm

  16. CFIRP: What we learned in the first ten years

    USGS Publications Warehouse

    Chambers, C.L.; McComb, W.C.; Tappeiner, J. C.; Kellogg, L.D.; Johnson, R.L.; Spycher, G.

    1999-01-01

    In response to public dissatisfaction with forest management methods, we initiated the College of Forestry Integrated Research Project (CFIRP) to test alternative silvicultural systems in Douglas-fir (Pseudotsuga menziesii stands in western Oregon. We compared costs and biological and human responses among a control and three replicated silvicultural alternatives to clearcutting that retained structural features found in old Douglas-fir forests. Treatments were applied within 8- to 15-ha stands and attempted to mimic crown fires (modified clearcut), windthrow (green tree retention), and small-scale impacts such as root rot diseases (small patch group selection). We also compared costs in three unreplicated treatments (large patch group selection, wedge cut, and strip cut). Each treatment included differences in the pattern of retained dead trees (snags), as either scattered individuals or as clumps. Good communication among researchers and managers, a long-term commitment to the project, and careful documentation of research sites and data are important to the success of long-term silvicultural research projects. To date, over 30 publications have resulted from the project.

  17. Ten years development of human resources in Serbian health system.

    PubMed

    Krstic, Maja; Grozdanov, Jasmina; Ivanovic, Ivan; Korac, Vesna; Vasic, Milena

    2010-01-01

    A key component of any healthcare reform process is to ensure that the services are delivered by the right numbers of staff with appropriate skills and training. In 2007, public health institutions in Serbia had 2% more employees than before the economic transition. Nevertheless, the trend of the total number of employees in the Serbian health care system still preserved a mild rising trend. The most prominent changes in the structure of human resources were effectuated in the total numbers of physicians, nurses and administrative and technical staff. Development of medical science and practice in Serbia is characterized by more intensive processes of specializations, resulting in increased number of specialists among medical doctors. Health care provided in in-patient institutions still employs most of the doctors. The number of unemployed physicians, dentists and pharmacists has been rising since 2000. Another aspect that explains the rise of unemployed, university educated human resources is the rising number of graduated physicians, dentist and pharmacists. Health care policy makers may recognize the need for more integrated planning of human resources in health care, in particular, making management of human resources responsive to system needs and design, instead of vice versa.

  18. Ten years of gene therapy for primary immune deficiencies.

    PubMed

    Aiuti, Alessandro; Roncarolo, Maria Grazia

    2009-01-01

    Gene therapy with hematopoietic stem cells (HSC) is an attractive therapeutic strategy for several forms of primary immunodeficiencies. Current approaches are based on ex vivo gene transfer of the therapeutic gene into autologous HSC by vector-mediated gene transfer. In the past decade, substantial progress has been achieved in the treatment of severe combined immundeficiencies (SCID)-X1, adenosine deaminase (ADA)-deficient SCID, and chronic granulomatous disease (CGD). Results of the SCID gene therapy trials have shown long-term restoration of immune competence and clinical benefit in over 30 patients. The inclusion of reduced-dose conditioning in the ADA-SCID has allowed the engraftment of multipotent gene-corrected HSC at substantial level. In the CGD trial significant engraftment and transgene expression were observed, but the therapeutic effect was transient. The occurrence of adverse events related to insertional mutagenesis in the SCID-X1 and CGD trial has highlighted the limitations of current retroviral vector technology. For future applications the risk-benefit evaluation should include the type of vector employed, the disease background and the nature of the transgene. The use of self-inactivating lentiviral vectors will provide significant advantages in terms of natural gene regulation and reduction in the potential for adverse mutagenic events. Following recent advances in preclinical studies, lentiviral vectors are now being translated into new clinical approaches, such as Wiskott-Aldrich Syndrome.

  19. [Ten years experience in Mali community health centers].

    PubMed

    Balique, H; Ouattara, O; Iknane, A A

    2001-03-01

    At the end of 10 years' existence, the community health centres of Mali show a way of organisation which meets the public health requirements and demands of financial viability of any health establishment. Their originality lays in several factors: their legal personality, their private status, their financial support of the medical staff, their management by a users association and the public utilities agreement they have signed with the department. In spite of their success which makes their numbers reach 350, they suffer from great deficiencies, which are resulted by the lack of democratic traditions within the associations, a inappropriate transparency of their accounts and an inefficient supervision from the part of the department. The main questions posed by this new experience concern the limits of the concept of community, the importance of citizenship in the development dynamics, the participation of private institutions in the accomplishment of public utilities, the jacobin and authoritarian attitude of the department representatives, the contradictions between multiplication of centres to improve geographic access and the requirements of financial viability.

  20. Ten-Year Experience of Remote Medical Education in Asia

    PubMed Central

    Kudo, Kuriko; Antoku, Yasuaki; Hu, Min; Okamura, Koji; Nakashima, Naoki

    2014-01-01

    Abstract Background: Moving images are often essential in medical education, to learn new procedures and advanced skills, but, in the past, high-quality movie transmission was technically much more challenging than transmitting still pictures because of technological limitations and cost. Materials and Methods: We established a new system, taking advantage of two advanced technologies, the digital video transport system (DVTS) and the research and education network (REN), which enabled satisfactory telemedicine on a routine basis. Results: Between 2003 and 2013, we organized 360 programs connecting 221 hospitals or facilities in 34 countries in Asia and beyond. The two main areas were endoscopy and surgery, with 113 (31%) and 106 (29%) events, respectively. Teleconferences made up 76% of the total events, with the remaining 24% being live demonstrations. Multiple connections were more popular (63%) than one-to-one connections (37%). With continuous technological development, new high-definition H.323 and Vidyo® (Hackensack, NJ) systems were used in 47% and 39% of events in 2011 and 2012, respectively. The evaluation by questionnaires was favorable on image and sound quality as well as programs. Conclusions: Remote medical education with moving images was well accepted in Asia with changing needs and developing technologies. PMID:25272006

  1. Lessons from ten years of crystallization experiments at the SGC

    PubMed Central

    Ng, Jia Tsing; Dekker, Carien; Reardon, Paul; von Delft, Frank

    2016-01-01

    Although protein crystallization is generally considered more art than science and remains significantly trial-and-error, large-scale data sets hold the promise of providing general learning. Observations are presented here from retrospective analyses of the strategies actively deployed for the extensive crystallization experiments at the Oxford site of the Structural Genomics Consortium (SGC), where comprehensive annotations by SGC scientists were recorded on a customized database infrastructure. The results point to the importance of using redundancy in crystallizing conditions, specifically by varying the mixing ratios of protein sample and precipitant, as well as incubation temperatures. No meaningful difference in performance could be identified between the four most widely used sparse-matrix screens, judged by the yield of crystals leading to deposited structures; this suggests that in general any comparison of screens will be meaningless without extensive cross-testing. Where protein sample is limiting, exploring more conditions has a higher likelihood of being informative by yielding hits than does redundancy of either mixing ratio or temperature. Finally, on the logistical question of how long experiments should be stored, 98% of all crystals that led to deposited structures appeared within 30 days. Overall, these analyses serve as practical guidelines for the design of initial screening experiments for new crystallization targets. PMID:26894670

  2. [Digestive tract cancer: after ten years in Santa Fe].

    PubMed

    Jiménez, Félix; Elias, Roberto Emanuel; Osella, Francisco Javier; Padilla, Juan Francisco Antonio

    2009-12-01

    In our earlier paper we found that esophageal cancer was the most frequent localization among all the digestive tract cancers. Furthermore, in four departments belonging to our province we also observed a colon-esophagus relationship of virtually 1 to 1. In this study we aimed to: 1) estimate the prevalence of esophagus and stomach tumors: a) in the Endoscopy Department, b) in all the hospital, comparing it with colon cancer and, c) as causes of death in our region of influence, in relation to all the neoplastic pathologies. 2) analyze the histological lineage and the anatomical location, according to sex, age and origin. We evaluated: 3,396 upper digestive tract endoscopies, the diagnoses of digestive tract cancer from the Histopathology Service, the discharges from hospital as the result of digestive tract cancer from the General Archives, all of them from Cullen Hospital, and death register of the province of Santa Fe accounting for digestive tract cancer. A descriptive analysis was carried out and spreadsheet from the Open Office 2.2 version and SPSS 10.0 version were used. We observed that esophageal cancer is still very frequent in the Endoscopy Department and in the Histopathology Service but not in the diagnoses at discharge from hospital. It shares similar epidemiological features to the ones observed in the international literature. The reduction of the relationship between colon and esophageal cancer in the global mortality rate of the country turns out to be surprising. In three departments situated on the north of the province it was observed a colon-esophagus cancer relationship of 1:1.

  3. Purpose in Life Predicts Allostatic Load Ten Years Later

    PubMed Central

    Zilioli, Samuele; Slatcher, Richard B.; Ong, Anthony D.; Gruenewald, Tara

    2015-01-01

    Objective Living a purposeful life is associated with better mental and physical health, including longevity. Accumulating evidence shows that these associations might be explained by the association between life purpose and regulation of physiological systems involved in the stress response. The aim of this study was to investigate the prospective associations between life purpose and allostatic load over a 10-year period. Methods Analyses were conducted using data from the Midlife in the United States (MIDUS) survey. Assessment of life purpose, psychological covariates and demographics were obtained at baseline, while biomarkers of allostatic load were assessed at the 10-year follow-up. Results We found that greater life purpose predicted lower levels of allostatic load at follow-up, even when controlling for other aspects of psychological well-being potentially associated with allostatic load. Further, life purpose was also a strong predictor of individual differences in self-health locus of control—i.e., beliefs about how much influence individuals can exert on their own health—which, in turn, partially mediated the association between purpose and allostatic load. Although life purpose was also negatively linked to other-health locus of control —i.e., the extent to which individuals believe their health is controlled by others/chance —this association did not mediate the impact of life purpose on allostatic load. Conclusion The current study provides the first empirical evidence for the long-term physiological correlates of life purpose and supports the hypothesis that self-health locus of control acts as one proximal psychological mechanism through which life purpose may be linked to positive biological outcomes. PMID:26526322

  4. Analysis of ten years of publishing in Pharmacy Practice

    PubMed Central

    Mendes, Antonio E.; Tonin, Fernanda S.; Fernandez-Llimos, Fernando

    2016-01-01

    Objective: The aim of this study is to characterize the patterns and trends in the editorial process and features of the first decade of Pharmacy Practice, with the final goal of initiating a benchmarking process to enhance the quality of the journal. Methods: Metadata of all of the articles published from 2006 issue #3 to 2016 issue #2 were extracted from PubMed and complemented by a manual data extraction process on the full-text articles. Citations of these articles were retrieved from Web of Science (WOS), Scopus, and Google Scholar on August 15, 2016. The references from all of the articles published by Pharmacy Practice in 2015 were also extracted. International collaboration was explored with a network analysis. Results: A total of 40 issues were published in this timespan, including 349 articles, 91.1% of which were original research articles. The number of citations received by these articles varies from 809, as reported by the WOS, to the 1162 reported by Scopus and the 2610 reported by Google Scholar. The journals cited by Pharmacy Practice are mainly pharmacy journals, including Pharm Pract (Granada), Int J Clin Pharm, Am J Health-Syst Pharm, Am J Pharm Educ, and Ann Pharmacother. Only 17.3% of the articles involved international collaboration. Delays in the editorial process increased in 2013, mainly due to an increase in acceptance delay (mean=138 days). Conclusion: Pharmacy Practice has improved its visibility and impact over the past decade, especially after 2014, when the journal became indexed in PubMed Central. The editorial process duration is one of the weaknesses that should be tackled. Further studies should investigate if the low international collaboration rate is common across other pharmacy journals. PMID:28042357

  5. Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy

    PubMed Central

    May, Margaret T.; Vehreschild, Janne; Obel, Niels; Gill, Michael John; Crane, Heidi; Boesecke, Christoph; Samji, Hasina; Grabar, Sophie; Cazanave, Charles; Cavassini, Matthias; Shepherd, Leah; d’Arminio Monforte, Antonella; Smit, Colette; Saag, Michael; Lampe, Fiona; Hernando, Vicky; Montero, Marta; Zangerle, Robert; Justice, Amy C.; Sterling, Timothy; Miro, Jose; Ingle, Suzanne; Sterne, Jonathan A. C.

    2016-01-01

    Objectives To estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996–1999 and survived for more than ten years. Methods We used data from 18 European and North American HIV cohort studies contributing to the Antiretroviral Therapy Cohort Collaboration. We followed up patients from ten years after start of combination antiretroviral therapy. We estimated overall and cause-specific mortality rate ratios for age, sex, transmission through injection drug use, AIDS, CD4 count and HIV-1 RNA. Results During 50,593 person years 656/13,011 (5%) patients died. Older age, male sex, injecting drug use transmission, AIDS, and low CD4 count and detectable viral replication ten years after starting combination antiretroviral therapy were associated with higher subsequent mortality. CD4 count at ART start did not predict mortality in models adjusted for patient characteristics ten years after start of antiretroviral therapy. The most frequent causes of death (among 340 classified) were non-AIDS cancer, AIDS, cardiovascular, and liver-related disease. Older age was strongly associated with cardiovascular mortality, injecting drug use transmission with non-AIDS infection and liver-related mortality, and low CD4 and detectable viral replication ten years after starting antiretroviral therapy with AIDS mortality. Five-year mortality risk was <5% in 60% of all patients, and in 30% of those aged over 60 years. Conclusions Viral replication, lower CD4 count, prior AIDS, and transmission via injecting drug use continue to predict higher all-cause and AIDS-related mortality in patients treated with combination antiretroviral therapy for over a decade. Deaths from AIDS and non-AIDS infection are less frequent than deaths from other non-AIDS causes. PMID:27525413

  6. Introduction to "Tsunami Science: Ten Years after the 2004 Indian Ocean Tsunami. Volume II."

    NASA Astrophysics Data System (ADS)

    Rabinovich, Alexander B.; Geist, Eric L.; Fritz, Hermann M.; Borrero, Jose C.

    2015-12-01

    Twenty papers on the study of tsunamis and respective tsunamigenic earthquakes are included in Volume II of the PAGEOPH topical issue "Tsunami Science: Ten Years after the 2004 Indian Ocean Tsunami". The papers presented in this second of two special volumes of Pure and Applied Geophysics reflect the state of tsunami science during this time, including five papers devoted to new findings specifically in the Indian Ocean. Two papers compile results from global observations and eight papers cover Pacific Ocean studies, focusing mainly on the 2011 Tohoku earthquake and tsunami. Remaining papers in this volume describe studies in the Atlantic Ocean and Mediterranean Sea and tsunami source studies. Overall, the volume not only addresses the pivotal 2004 Indian Ocean and 2011 Tohoku tsunamis, but also examines the tsunami hazard posed to other critical coasts in the world.

  7. Introduction to "Tsunami Science: Ten Years After the 2004 Indian Ocean Tsunami. Volume I"

    NASA Astrophysics Data System (ADS)

    Rabinovich, Alexander B.; Geist, Eric L.; Fritz, Hermann M.; Borrero, Jose C.

    2015-03-01

    Twenty-two papers on the study of tsunamis are included in Volume I of the PAGEOPH topical issue "Tsunami Science: Ten Years after the 2004 Indian Ocean Tsunami." Eight papers examine various aspects of past events with an emphasis on case and regional studies. Five papers are on tsunami warning and forecast, including the improvement of existing tsunami warning systems and the development of new warning systems in the northeast Atlantic and Mediterranean region. Three more papers present the results of analytical studies and discuss benchmark problems. Four papers report the impacts of tsunamis, including the detailed calculation of inundation onshore and into rivers and probabilistic analysis for engineering purposes. The final two papers relate to important investigations of the source and tsunami generation. Overall, the volume not only addresses the pivotal 2004 Indian Ocean (Sumatra) and 2011 Japan (Tohoku) tsunamis, but also examines the tsunami hazard posed to other critical coasts in the world.

  8. Evaluation of Nutritional Biochemical Parameters in Haemodialysis Patients over a Ten-year Period

    PubMed Central

    Alfonso, AIQ; Castillo, RF; Jimenez, FJ Gomez; Negrillo, AM Nuñez

    2015-01-01

    ABSTRACT Aim: Protein-energy malnutrition as well as systemic inflammation and metabolic disorders are common in patients with chronic kidney failure who require renal replacement therapy (haemodialysis). Such malnutrition is a factor that significantly contributes to their morbidity and mortality. This study evaluated the nutritional status of haemodialysis patients by assessing biochemical and anthropometric parameters in order to determine whether these patients suffered disorders reflecting nutritional deterioration directly related to time on haemodialysis. Subjects and Method: This research comprised 90 patients of both genders with chronic kidney failure, who regularly received haemodialysis at our unit over a period of ten years. The patients' blood was tested quarterly for plasma albumin, total cholesterol and total proteins, and tested monthly for transferrin. The patients' weight, height and body mass index (BMI) were monitored. Body mass index was calculated using the formula: weight (kg)/height (m2) and classified in one of the following categories defined in the World Health Organization (WHO) Global Database on Body Mass Index: (i) underweight [BMI < 18.50], (ii) normal [BMI 18.50 – 24.99], (iii) overweight [BMI 25 – 29.99], (iv) obese [BMI ≥ 30]. Results: In the ten-year period of the study, the patients experienced a substantial decline in their biochemical parameters. Nevertheless, their BMI did not show any significant changes despite the patients' state of malnutrition. Conclusions: The prevalence of malnutrition in haemodialysis patients was evident. Nevertheless, the BMI of the subjects did not correspond to the biochemical parameters measured. Consequently, the results showed that the nutritional deterioration of these patients was mainly reflected in their biochemical parameters rather than in their anthropometric measurements. PMID:26426172

  9. Effectiveness of different methods to control legionella in the water supply: ten-year experience in an Italian university hospital.

    PubMed

    Marchesi, I; Marchegiano, P; Bargellini, A; Cencetti, S; Frezza, G; Miselli, M; Borella, P

    2011-01-01

    We report our ten-year experience of hyperchlorination, thermal shock, chlorine dioxide, monochloramine, boilers and point-of-use filters for controlling legionella contamination in a hospital hot water distribution system. Shock disinfections were associated with a return to pre-treatment contamination levels within one or two months. We found that chlorine dioxide successfully maintained levels at <100 cfu/L, whilst preliminary experiments gave satisfactory results with monochloramine. No contamination was observed applying point-of-use filters and electric boilers at temperatures of >58°C and no cases of nosocomial legionellosis were detected in the ten-year observation period. Our performance ranking in reducing legionella contamination was filter, boiler, chlorine dioxide, hyperchlorination and thermal shock. Chlorine dioxide was the least expensive procedure followed by thermal shock, hyperchlorination, boiler and filter. We suggest adopting chlorine dioxide and electric boilers in parallel.

  10. Ten years of negotiating rights around maternal health in Uttar Pradesh, India

    PubMed Central

    2011-01-01

    Background Preventable maternal mortality and morbidity have been globally recognized as human rights issues. Maternal mortality in India is among the highest in the world, and reflects inequity in access to healthcare: women from certain states as well as poorer women and less literate women appear to be significantly disadvantaged. The government of India has been attempting to improve maternal outcomes through a cash transfer within the National Rural Health Mission to encourage women to come to hospitals for childbirth. Methods This paper reviews documents of the last ten years describing the experiences of a Non-Governmental Organisation, SAHAYOG, in working with a civil society platform, the Healthwatch Forum, to develop ‘rights based’ strategies around maternal health. The paper builds an analysis using recent frameworks on accountability and gendered rights claiming to examine these experiences and draw out lessons regarding rights claiming strategies for poor women. Results The examination of documents over the last ten years indicates defined phases of development in the evolution of SAHAYOG’s understanding and of the shifts in strategy among SAHAYOG and its close allies, and responses by the state. The first three stages depict the deepening of SAHAYOG’s understanding of the manner in which poor and marginalized women negotiate their access to health care; the fourth stage explores a health system intervention and the challenges of working from within civil society in alliance with poor and marginalized women. Conclusion The findings from SAHAYOG’s experiences with poor Dalit women in Uttar Pradesh reveal the elements of social exclusion within the health system that prevent poor and marginalized women from accessing effective lifesaving care. Creating a voice for the most marginalised and carving space for its articulation impacts upon the institutions and actors that have a duty to meet the claims being made. However, given the accountability

  11. Long-Term Clinical Outcomes of Invasive Giant Prolactinomas after a Mean Ten-Year Followup

    PubMed Central

    Wu, Ze Rui; Zhang, Yong; Lin, Shao Jian; Su, Zhi Peng; Wei, Yong Xu; Shang, Han Bing; Yang, Wen Lei; Zhao, Wei Guo

    2016-01-01

    Objective. The aim of this study is to observe clinical outcomes after more than ten years of followup in a group of patients with invasive giant prolactinomas (IGPs) treated with dopamine agonists (DAs). Methods. Twenty-five patients met the criteria of IGPs, among which 16 patients primarily received bromocriptine (BRC) and the other nine had undergone unsuccessful microsurgery prior to BRC treatment. Results. After a mean follow-up period of 135.5 ± 4.7 months, the clinical symptoms in all patients improved by different degrees. Tumor volume was decreased by a mean of 98.6%, and the tumors of 19 patients had almost completely disappeared. The mean duration of treatment at maximal doses of BRC was 48.5 months. At the last follow-up visit, nineteen patients had normal PRL levels, and 14 of these patients had received the low-dose BRC treatment (at an average of 2.9 ± 0.3 mg/d). Younger patients < 25 years had a significantly higher rate of persistent hyperprolactinemia after long-term BRC treatment (p = 0.043). Conclusion. DAs are a first-line therapy for IGPs because they can effectively achieve long-term control in both shrinking tumor volume and normalizing the PRL level, and majority of patients need low-dose DA maintenance. Younger patients are prone to persistent hyperprolactinemia despite long-term DA treatment. PMID:27999593

  12. Ten-year helium anomaly prior to the 2014 Mt Ontake eruption.

    PubMed

    Sano, Yuji; Kagoshima, Takanori; Takahata, Naoto; Nishio, Yoshiro; Roulleau, Emilie; Pinti, Daniele L; Fischer, Tobias P

    2015-08-19

    Mt Ontake in central Japan suddenly erupted on 27(th) September 2014, killing 57 people with 6 still missing. It was a hydro-volcanic eruption and new magmatic material was not detected. There were no precursor signals such as seismicity and edifice inflation. It is difficult to predict hydro-volcanic eruptions because they are local phenomena that only affect a limited area surrounding the explosive vent. Here we report a long-term helium anomaly measured in hot springs close to the central cone. Helium-3 is the most sensitive tracer of magmatic volatiles. We have conducted spatial surveys around the volcano at once per few years since November 1981. The (3)He/(4)He ratios of the closest site to the cone stayed constant until June 2000 and increased significantly from June 2003 to November 2014, while those of distant sites showed no valuable change. These observations suggest a recent re-activation of Mt Ontake and that helium-3 enhancement may have been a precursor of the 2014 eruption. We show that the eruption was ultimately caused by the increased input of magmatic volatiles over a ten-year period which resulted in the slow pressurization of the volcanic conduit leading to the hydro-volcanic event in September 2014.

  13. Ten-year helium anomaly prior to the 2014 Mt Ontake eruption

    PubMed Central

    Sano, Yuji; Kagoshima, Takanori; Takahata, Naoto; Nishio, Yoshiro; Roulleau, Emilie; Pinti, Daniele L.; Fischer, Tobias P.

    2015-01-01

    Mt Ontake in central Japan suddenly erupted on 27th September 2014, killing 57 people with 6 still missing. It was a hydro-volcanic eruption and new magmatic material was not detected. There were no precursor signals such as seismicity and edifice inflation. It is difficult to predict hydro-volcanic eruptions because they are local phenomena that only affect a limited area surrounding the explosive vent. Here we report a long-term helium anomaly measured in hot springs close to the central cone. Helium-3 is the most sensitive tracer of magmatic volatiles. We have conducted spatial surveys around the volcano at once per few years since November 1981. The 3He/4He ratios of the closest site to the cone stayed constant until June 2000 and increased significantly from June 2003 to November 2014, while those of distant sites showed no valuable change. These observations suggest a recent re-activation of Mt Ontake and that helium-3 enhancement may have been a precursor of the 2014 eruption. We show that the eruption was ultimately caused by the increased input of magmatic volatiles over a ten-year period which resulted in the slow pressurization of the volcanic conduit leading to the hydro-volcanic event in September 2014. PMID:26286468

  14. Teacher Professional Development in "Teaching and Teacher Education" over Ten Years

    ERIC Educational Resources Information Center

    Avalos, Beatrice

    2011-01-01

    A review of publications in "Teaching and Teacher Education" over ten years (2000-2010) on teacher professional development is the subject of the paper. The first part synthesises production referred to learning, facilitation and collaboration, factors influencing professional development, effectiveness of professional development and issues…

  15. Mathematical Skills in Undergraduate Students. A Ten-Year Survey of a Plant Physiology Course

    ERIC Educational Resources Information Center

    Llamas, A.; Vila, F.; Sanz, A.

    2012-01-01

    In the health and life sciences and many other scientific disciplines, problem solving depends on mathematical skills. However, significant deficiencies are commonly found in this regard in undergraduate students. In an attempt to understand the underlying causes, and to improve students' performances, this article describes a ten-year survey…

  16. The Career Fair Project: A Ten Year Experiment in Performance-Based Learning

    ERIC Educational Resources Information Center

    Stewart, Vicki

    2005-01-01

    This article summarizes my experiences in developing an educational initiative known as the Career Fair Project within the curriculum of the Legal Administration/Law Clerk program at Durham College over the past ten years. A performance-based, student-centered project, the Career Fair empowers students to work collaboratively with one another in…

  17. Technology in Science Education: The Next Ten Years: Perspectives and Recommendations.

    ERIC Educational Resources Information Center

    Licklider, J. C. R.; And Others

    The four papers in this collection were commissioned by the Science Education Directorate of the National Science Foundation to assist in planning a research agenda for science education for the next ten years. A background paper by Dr. J.C.R. Licklider, "Impact of Information Technology on Education in Science and Technology," discusses the…

  18. Adult and Continuing Education: The Next Ten Years. Information Series No. 114.

    ERIC Educational Resources Information Center

    Grabowski, Stanley M.

    Futurism for adult and continuing education in the next ten years is the focus of this information analysis paper intended for adult educators and researchers. The paper is based on (1) literature practices in the field, (2) discussions with colleagues, (3) personal observations and experiences, (4) participation in futures conferences about adult…

  19. "Ten Years On": Making Children Visible in Teacher Education and Ways of Reading Video

    ERIC Educational Resources Information Center

    Burke, Catherine; Cunningham, Peter

    2011-01-01

    "Ten Years On" is a 30-minute video documentary discovered in the course of researching progressive primary education, school architecture and pedagogy. It was locally produced for professional rather than commercial use at a significant historical moment for educational politics and primary practice. Here, we explore the possibilities…

  20. Ten Years on: Does Graduate Student Promise Predict Later Scientific Achievement?

    ERIC Educational Resources Information Center

    Haslam, Nick; Laham, Simon M.

    2009-01-01

    We examined publication records of 60 social psychologists to determine whether publication record at the time of the PhD (t0) predicted scientific achievement (publication quantity, quality, and impact) ten years later (t10). Publication quantity and quality each correlated moderately across this time-span. Productivity and impact at t10 were…

  1. TOJDE: Electronic Publishing and a Review of Ten Years' Experience in Turkey

    ERIC Educational Resources Information Center

    Ozarslan, Yasin; Balaban-Sali, Jale; Demiray, Ugur

    2012-01-01

    This review examines "The Turkish Online Journal of Distance Education" (TOJDE) over a ten years period from 2000-2010. The study provides an opportunity to examine publishing activities such as number of published articles, authors, research topics and methods, and analyses of TOJDE's website such as time users stay on site and user…

  2. Changing Course: Ten Years of Tracking Online Education in the United States

    ERIC Educational Resources Information Center

    Allen, I. Elaine; Seaman, Jeff

    2013-01-01

    "Changing Course: Ten Years of Tracking Online Education" in the United States is the tenth annual report on the state of online learning in U.S. higher education. The survey is designed, administered and analyzed by the Babson Survey Research Group. Data collection is conducted in partnership with the College Board. This year's study, like those…

  3. Ten Years Later: A Follow-Up Study of Professors Still Working after Age 70

    ERIC Educational Resources Information Center

    Dorfman, Lorraine T.

    2009-01-01

    Little is known about the impact of the end of mandatory retirement on professors over the long term. This follow-up study investigated the ten-year experience of professors who chose not to retire from a major research university after the elimination of the age 70 mandatory retirement in 1994. The initial interview study was conducted in 1998…

  4. Quality of Life in South Africa--The First Ten Years of Democracy

    ERIC Educational Resources Information Center

    Moller, Valerie

    2007-01-01

    South Africa celebrated ten years of democracy in 2004. This special issue of "Social Indicators Research" ("SIR") reviews developments that have impacted on the quality of life of ordinary South Africans during the transition period. The issue updates an earlier volume of "SIR" (Volume 41) published in 1997 and as a…

  5. [Reflections on some methodological errors in the evaluation of drugs. Ten years experience at the National Marketing Authorization Commission].

    PubMed

    Bouvenot, G

    2001-01-01

    A ten year experience at the national french marketing authorization committee has permitted to notice the most commonly methodological errors in the field of clinical research and, particularly, in the dossiers for drug approval: a frequent insufficient sample size resulting in lack of statistical power, an unsatisfactory optimal dosing research, a misuse of the so-called surrogate markers, an erroneous opinion about the meaning of the p value, an abusive claim for equivalence in non significant superiority trials, a misuse of unadjusted multiple comparisons and too much confidence in subgroup analysis results.

  6. Ten years of RELEA: achievements and challenges for astronomy education development

    NASA Astrophysics Data System (ADS)

    Bretones, Paulo Sergio; Jafelice, Luiz Carlos; Horvath, Jorge Ernesto

    2015-08-01

    When an area of education, and more particularly the research within this area, is aimed to development, a basic requirement is the existence of a regular publication that accounts for the scientific production in that area. This study aims to analyze 10 years of Latin-American Journal of Astronomy Education (RELEA). Publishing policies of the RELEA and their context are discussed in relation to submission, refereeing and publication. The 75 articles published in 18 editions are analyzed and classified by: year of publication, edition, the authors' institutions, school level, study focus and content. The results present trends and shortcomings of the production. A comparison with the number of articles published in other Brazilian journals of education and an analysis of the international scene in relation to other type publications along these ten years is made. Given that this journal is now consolidated, its future prospects in the international landscape are further considered. The challenges related to article submission are discussed: how to increase their number, the submission of Latin American countries, and how to bring in the issues and subjects not addressed until now. It is also considered the possibility of encouraging graduate studies, new lines of research in astronomy education, and dissemination of material in schools and universities for teachers and students. Finally, future possibilities are discussed given the IAU development programs. For example, more article submission from Portuguese-speaking countries with the support of Regional Nodes and Language Expertise Centers, and opportunities for volunteer IAU members and global projects for the development of astronomy education.

  7. [Phenology of forest vegetation in northeast of China in ten years using remote sensing].

    PubMed

    Hou, Xue-Hui; Niu, Zheng; Gao, Shuai

    2014-02-01

    Plant phenology is the best indicator of terrestrial ecosystem response to climate change and it becomes a hot issue in the study of global change. The forest in northeast of China plays an important part in global forest ecosystem. In this paper, yearly integrated Normalized Difference Vegetation Index (NDVI) of forest vegetation in northeast China was calculated based on Spot Vegetation datasets from 2001-2010, which has been filtered using Savtiky-Galoy method. And then, the yearly integrated NDVI profile was fitted using a logistic model. Two key parameters of forest phenology (start of season, SOS; end of season, EOS) were extracted according to the greatest rate of curvature of fitted cumulative NDVI and the length of forest phenology (length of season, LOS) was also analyzed. The main conclusions of this paper are (1) SOS mainly occurs in the 110th-140th day and EOS in 260th and 290th day. SOS displays a marked delayed from south to north while EOS gradually advances. However, the changes of SOS and EOS in ten years are not obvious. (2) Corresponding to the SOS and EOS, LOS of forest in study area mainly occurs in the 120th-160th day; however, it is spatially heterogeneous. LOS of forest in Greater Khingan Mountains is shorter (about 120-140 day) than forests in Xiao Hinggan Ling and Changbai Mountains (about 160 day). The results in this paper are concordant with records of phenology in situ measurements and previous researches in the same area. It indicates that forest phenophases using method in this paper from Spot Vegetation dataset is feasible.

  8. Review of ten-years presence of Aedes albopictus in Spain 2004-2014: known distribution and public health concerns.

    PubMed

    Collantes, Francisco; Delacour, Sarah; Alarcón-Elbal, Pedro María; Ruiz-Arrondo, Ignacio; Delgado, Juan Antonio; Torrell-Sorio, Antonio; Bengoa, Mikel; Eritja, Roger; Miranda, Miguel Ángel; Molina, Ricardo; Lucientes, Javier

    2015-12-23

    Ten years have gone by since the Asian tiger mosquito Aedes albopictus was recorded for the first time in Spain. In this paper, all relevant published information about this vector in Spain for the period 2004-2014 is reviewed. The known distribution for 2014 is provided, including all historical records (published and unpublished data) and the results from samplings of the last year. The consequences on public health about the presence of the Asian tiger mosquito in Spain are also highlighted. Further, legal aspects and control plans related to the management and diseases transmitted by this invasive vector species are also discussed.

  9. Upper extremity snowboarding injuries. Ten-year results from the Colorado snowboard injury survey.

    PubMed

    Idzikowski, J R; Janes, P C; Abbott, P J

    2000-01-01

    A survey of snowboarding injuries was conducted over 10 seasons (1988 to 1998). A questionnaire evaluating 20 variables was used to collect data from 47 medical facilities near Colorado ski resorts. A total of 7430 snowboarding-related injuries were seen. A control group consisted of 3107 noninjured snowboarders. Most of those injured were 30 years of age or younger; 74% of injuries occurred in men and 26% in women; 39% of injured snowboarders were beginners and 61% were intermediate or experts. Men rode at more advanced levels than women. Injured snowboarders were more likely than noninjured snowboarders to be beginners. There were 3645 (49.06% of total) upper extremity injuries; 56.43% were fractures, 26.78% sprains, and 9.66% dislocations. The most common site of injury was the wrist (21.6% of all snowboarding injuries). Wrist fractures (except to the scaphoid) and sprains were more common in beginners, women, and younger age groups. Intermediate and expert men were more likely to sustain hand, elbow, and shoulder injuries, as well as more severe injuries. Falling was the predominant mechanism of upper extremity injuries. Snowboarders who wore protective wrist guards were half as likely to sustain wrist injuries as those who did not wear guards.

  10. Study Results from the Clinical Trials Network’s First Ten Years: Where Do They Lead?

    PubMed Central

    Wells, Elizabeth A.; Saxon, Andrew J.; Calsyn, Donald A.; Jackson, Thomas R.; Donovan, Dennis M.

    2010-01-01

    The National Drug Abuse Treatment Clinical Trials Network (CTN) began in 2000 with the goal of “improv[ing] the quality of drug abuse treatment throughout the country using science as the vehicle.” Since then, 24 discrete clinical trials were launched, 20 are completed, and 15 have published main outcome papers. Of the latter, four tested pharmacological treatment, eight, psychosocial/behavioral treatment, one, a combination of medication and counseling, and two targeted HIV/HCV risk behavior. We review main study findings for these trials, including treatment retention, substance use or risk behavior outcomes, and secondary outcomes when analyzed. The purpose of this review is to identify the incremental progress toward improving drug treatment made by these trials and to propose next steps for the CTN and for the field arising from these studies. The CTN provides a unique opportunity to systematically design trials that incorporate treatment improvements from previous trials and to direct efforts toward innovations most likely to be incorporated into practice. PMID:20307792

  11. Ten Years of Northern Eurasia Earth Science Partnership Initiative (NEESPI): Results and Future Plans

    NASA Astrophysics Data System (ADS)

    Groisman, P. Y.; Gutman, G.; Gulev, S.; Maksyutov, S. S.

    2014-12-01

    During recent decades, Northern Eurasia was affected by unprecedented climate and environmental changes. Several droughts and heat waves alternated with hazardous extreme precipitation and flood events. Permafrost thaw, retreating Arctic sea ice, increasing areas of forest fire, and dramatic regional warming buffeted this region, tossing northern Eurasia from one extreme condition to the next. The region stores nearly half of the Earth's terrestrial carbon in permafrost, wetlands, and forested land, so ecosystem changes that release stored carbon could profoundly affect the world's climate. Furthermore, changes to climate and to hydrological and biogeochemical cycles are starting to affect daily life. For example, infrastructure is collapsing as permafrost thaws, severe winter storms increasingly bring businesses to a halt, and a growing water deficit is beginning to strain agricultural production and forestry. To pool resources and facilitate research, the Northern Eurasia Earth Science Partnership Initiative (NEESPI, http://neespi.org) was launched in 2004. With its multidisciplinary focus, the internationally funded NEESPI (more than165 individual international projects during the past decade) has challenged participants to research climate-ecosystem interactions, societal impacts from extreme events in Northern Eurasia, and the feedbacks of these interactions and impacts to the global Earth system. Among the numerous Institutional and private sponsors from the United States, European Union, Russia, China, and Japan, the cornerstone support for the NEESPI studies was provided by the NASA Land Cover and Land Use Change Program and the Russian Academy of Sciences. At this presentation we shall overview the environmental studies conducted by the NEESPI community, brief the audience about the main achievements of the NEESPI researchers, and lay down the plans for the future studies. At the side event of the Meeting, we are going to initiate preparation of the book which will synthesize major NEESPI achievements.

  12. Neurobiology of Developmental Dyslexia: Results of a Ten Year Research Program.

    ERIC Educational Resources Information Center

    Galaburda, Albert M.

    1997-01-01

    This paper summarizes research currently being conducted on the biologic underpinnings of learning disorders, particularly dyslexia. The research findings discussed are derived from studying neuroanatomic, neurophysiologic, neurogenetic, neuroimaging, and behavioral characteristics in animal models that exhibit developmental brain anomalies and…

  13. [Stabilizing effect of orthokeratology lenses (ten-year follow-up results)].

    PubMed

    Tarutta, E P; Verzhanskaya, T Yu

    2017-01-01

    The global prevalence of myopia in adults varies between 20-50% in Europe and the US and 60-90% in Asian countries. According to WHO, myopia is one of the five leading causes of blindness and low vision in the world. Prevention or deceleration of myopia progression is an important public health problem. In recent years, orthokeratology (ortho-k) contact lenses worn at night have been found effective in slowing down the progression of myopia, however, the follow-up period in related studies is no longer than five years.

  14. Ten Commandments Revisited: A Ten-Year Perspective on the Industrial Application of Formal Methods

    NASA Technical Reports Server (NTRS)

    Bowen, Jonathan P.; Hinchey, Michael G.

    2005-01-01

    Ten years ago, our 1995 paper Ten Commandments of Formal Methods suggested some guidelines to help ensure the success of a formal methods project. It proposed ten important requirements (or "commandments") for formal developers to consider and follow, based on our knowledge of several industrial application success stories, most of which have been reported in more detail in two books. The paper was surprisingly popular, is still widely referenced, and used as required reading in a number of formal methods courses. However, not all have agreed with some of our commandments, feeling that they may not be valid in the long-term. We re-examine the original commandments ten years on, and consider their validity in the light of a further decade of industrial best practice and experiences.

  15. Pathological fracture of the femur ten years after successful radiation therapy for metastatic breast cancer.

    PubMed

    Hatano, Hiroshi; Morita, Tetsuro; Kobayashi, Hiroto; Ito, Takui; Segawa, Hiroyuki; Saito, Mari

    2004-01-01

    We describe a case involving a 75-year-old woman presenting with a femur fracture 10 years after radiation therapy for metastatic breast cancer, which developed in the right femur. The lesion showed complete response with bone healing following radiation therapy; however, the patient sustained a femur fracture ten years later. Histological examination of the specimens obtained from the lesion revealed features of radiation osteonecrosis, but there was no histological evidence of tumor. To our knowledge, there has been no reported case of pathological fracture ten years after radiation therapy from radiation osteonecrosis rather than progression of the metastatic lesion. Late complications of radiation therapy should be considered with care, even when metastatic lesions demonstrate complete response to treatment.

  16. Injection-molded 1-3 piezocomposite sensor development: The last ten years

    NASA Astrophysics Data System (ADS)

    Benjamin, Kim C.

    2005-04-01

    The past ten years have seen several interesting demonstrations of 1-3 piezocomposite when used as the active component in sonar sensors. Initially considered receive only by most in the field, piezocomposite has evolved into a proven broadband transducer material with both receive and transmit capability. From large aperture single element calibration transducers, to parametric mode projectors, the material has surprised many experts with its power handling capability. Its polymer constituent provides an amazing degree of versatility by allowing the thermoforming and shaping of transducer substrates for packaging into todays undersea vehicles. This talk will review the last ten years of piezocomposite transducer and array development focusing on both the materials transmit behavior and fabrication benefits for future sonar applications. [Work supported by the U.S. Navy.

  17. Ten-year monitoring of high-rise building columns using long-gauge fiber optic sensors

    NASA Astrophysics Data System (ADS)

    Glisic, B.; Inaudi, D.; Lau, J. M.; Fong, C. C.

    2013-05-01

    A large-scale lifetime building monitoring program was implemented in Singapore in 2001. The monitoring aims of this unique program were to increase safety, verify performance, control quality, increase knowledge, optimize maintenance costs, and evaluate the condition of the structures after a hazardous event. The first instrumented building, which has now been monitored for more than ten years, is presented in this paper. The long-gauge fiber optic strain sensors were embedded in fresh concrete of ground-level columns, thus the monitoring started at the birth of both the construction material and the structure. Measurement sessions were performed during construction, upon completion of each new story and the roof, and after the construction, i.e., in-service. Based on results it was possible to follow and evaluate long-term behavior of the building through every stage of its life. The results of monitoring were analyzed at a local (column) and global (building) level. Over-dimensioning of one column was identified. Differential settlement of foundations was detected, localized, and its magnitude estimated. Post-tremor analysis was performed. Real long-term behavior of concrete columns was assessed. Finally, the long-term performance of the monitoring system was evaluated. The researched monitoring method, monitoring system, rich results gathered over approximately ten years, data analysis algorithms, and the conclusions on the structural behavior and health condition of the building based on monitoring are presented in this paper.

  18. Outcomes of Open Carpal Tunnel Release at a Minimum of Ten Years

    PubMed Central

    Louie, Dexter L.; Earp, Brandon E.; Collins, Jamie E.; Losina, Elena; Katz, Jeffrey N.; Black, Eric M.; Simmons, Barry P.; Blazar, Philip E.

    2013-01-01

    Background: There is little research on the long-term outcomes of open carpal tunnel release. The purpose of this retrospective study was to determine the functional and symptomatic outcomes of patients at a minimum of ten years postoperatively. Methods: Two hundred and eleven patients underwent open carpal tunnel release from 1996 to 2000 performed by the same hand fellowship-trained surgeon. Follow-up with validated self-administered questionnaire instruments was conducted an average of thirteen years after surgery. The principal outcomes included the Levine-Katz symptom and function scores, ranging from 1 point (best) to 5 points (worst), and satisfaction with the results of surgery. The patients self-reported current comorbidities. Results: After a mean follow-up of thirteen years (range, eleven to seventeen years), 92% (194) of 211 patients were located. They included 140 who were still living and fifty-four who had died. Seventy-two percent (113) of the 157 located, surviving patients responded to the questionnaire. The mean Levine-Katz symptom score (and standard deviation) was 1.3 ± 0.5 points, and 13% of patients had a poor symptom score (≥2 points). The mean Levine-Katz function score was 1.6 ± 0.8 points, and 26% had a poor function score (≥2 points). The most common symptom-related complaint was weakness in the hand, followed by diurnal pain, numbness, and tingling. The least common symptoms were nocturnal pain and tenderness at the incision. Eighty-eight percent of the patients were either completely satisfied or very satisfied with the surgery. Seventy-four percent reported their symptoms to be completely resolved. Thirty-three percent of men were classified as having poor function compared with 23% of women. Two (1.8%) of 113 patients underwent repeat surgery. Conclusions: At an average of thirteen years after open carpal tunnel release, the majority of patients are satisfied and free of symptoms of carpal tunnel syndrome. Level of Evidence

  19. Ten Year Experience with Prosthetic Graft Infections Involving the Femoral Artery

    PubMed Central

    Siracuse, Jeffrey J; Nandivada, Prathima; Giles, Kristina A; Hamdan, Allen D; Wyers, Mark C; Chaikof, Elliot L; Pomposelli, Frank B; Schermerhorn, Marc L

    2013-01-01

    Background Prosthetic graft infection is a major complication of peripheral vascular surgery. We investigated our institution’s experience over ten years with bypass grafts involving the femoral artery to determine the incidence and risk factors for prosthetic graft infection. Methods A retrospective cohort single institution review of prosthetic bypass grafts involving the femoral artery from 2001–2010 evaluated patient demographics, body mass index, comorbidities, indications, location of bypass, type of prosthetic material, case urgency, previous ipsilateral bypass or percutaneous interventions; and evaluated the incidence of graft infections, amputations, and mortality. Results There were 496 prosthetic grafts identified with a graft infection rate of 3.8% (n=19) at a mean follow-up of 27 months. Multivariable analysis shows that redo bypass (HR 5.8, 95% CI 2.2–15.0), active infection at time of bypass (HR 5.2, 95% CI 1.9–14.2), female gender (HR 4.5, 95% CI 1.6–12.7), and diabetes mellitus (HR 4.6, 95% CI 1.5–14.3) were significant predictors of graft infection. Graft infection was predictive of major lower extremity amputation (HR 9.8, 95% CI 3.5–27.1) as was preoperative tissue loss (HR 4.7, 95% CI 1.8–11.9). Graft infection did not predict long term mortality, however chronic renal insufficiency (HR 2.3, 95% CI 1.6–3.4), tissue loss (HR 1.4, 95% CI 1.0–1.9), and active infection (HR 2.3, 95% CI 1.6–3.4) did. Infected grafts were removed 79% of the time. Staphylococcus epidermidis (37%) and Methicillin-sensitive Staphylococcus aureus (26%) were the most common pathogens isolated. Conclusions Redo-bypass, female gender, diabetes, and active infection at time of bypass are associated with a higher risk for prosthetic graft infection and major extremity amputation, but do not confer an increased risk of mortality. Autologous vein for lower extremity bypass and endovascular interventions should be considered when feasible in high

  20. Idaho National Laboratory 2013-2022 Ten-Year Site Plan

    SciTech Connect

    Calvin Ozaki; Sheryl L. Morton; Elizabeth A. Connell; William T. Buyers; Craig L. Jacobson; Charles T. Mullen; Christopher P. Ischay; Ernest L. Fossum; Robert D. Logan

    2011-06-01

    The Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of transforming the laboratory to meet Department of Energy (DOE) national nuclear research and development (R&D) goals, as outlined in DOE strategic plans. The plan links R&D mission goals and INL core capabilities with infrastructure requirements (single- and multi-program), establishs the 10-year end-state vision for INL complexes, and identifies and prioritizes infrastructure needs and capability gaps. The TYSP serves as the basis for documenting and justifying infrastructure investments proposed as part of the FY 2013 budget formulation process.

  1. Dopa-Responsive Dystonia in a Ten-Year-Old Girl

    PubMed Central

    Soma, Venkatesh; Mohammed, Hussain Sadiq; Riyas, Ebrahim; Murugesan, Karuppasamy

    2012-01-01

    Children with recent onset dystonia and gait abnormalities may pose a diagnostic challenge. A ten-year-old, developmentally normal girl, presented with a six-month history of gait abnormality and dystonia. Her complaint worsened as the day progressed. In view of typical diurnal variation of dystonia, a therapeutic challenge with levodopa/carbidopa was given and there was a dramatic response. Hence, a diagnosis of dopa-responsive dystonia (DRD) was made. DRD is an inherited disorder characterized by dystonia with diurnal variation and favorable response to levodopa/carbidopa. The inheritance is usually autosomal dominant, however, in some cases, autosomal-recessive inheritance is also seen. PMID:24479026

  2. European Security and Defense Policy (ESDP) After Ten Years - Current Situation and Perspectives

    DTIC Science & Technology

    2010-01-01

    Security Studies (ISS), Paris 2004. Solana, Javier . “Preface,” in: What Ambitions for European Defense in 2020?, ed. Alvaro de Vasconcelos, EU...Policy is not longer an aspiration; it is a reality.2 - Javier Solana ­ Now ten years in the making, the European Security and Defense Policy (ESDP) has...premier_ministre/2008/11-novembre/16­ juncker/index.html - accessed 14 September 2009. 2 Javier Solana, “Preface,” in: What Ambitions for European Defense in

  3. [Sexual complaints and dysfunction among PLHIV receiving ARV treatment for ten years in Senegal].

    PubMed

    Diaw, J; Taverne, B; Coutherut, J

    2014-10-01

    The sexual health of people who have been living with HIV (PLHIV) and who have been receiving ARV drug treatment for several years is still a virtually unexplored topic in Africa today. A study was conducted in Senegal on people who have been treated with ARVs for ten years. Half of those interviewed believe that their sexuality has deteriorated. HIV infection has become a chronic disease in which sexual dysfunction related to the disease or age is interpreted in the context of popular representations of HIV infection and those on sexuality defined by social norms.

  4. 76 FR 9787 - NIOSH Dose Reconstruction Program Ten Year Review-Phase I Report on Quality of Science; Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention NIOSH Dose Reconstruction Program Ten Year... review and comment on the draft publication, ``NIOSH Dose Reconstruction Program Ten Year Review--Phase...

  5. 76 FR 9786 - NIOSH Dose Reconstruction Program Ten-Year Review-Phase I Report on Customer Service; Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention NIOSH Dose Reconstruction Program Ten-Year... review and comment on the draft publication, ``NIOSH Dose Reconstruction Program Ten-Year Review--Phase...

  6. ``Long-life`` aluminium brazing alloys for automotive radiators -- a ten-year retrospective

    SciTech Connect

    Scott, A.C.; Woods, R.A.

    1998-12-31

    A class of corrosion-resistant brazing sheet materials, generally referred to as ``long-life alloys,`` has been in widespread use in brazed aluminum automobile radiators for over ten years. K319 tube material was initially introduced in 1986 to address the problem of road-salt-induced, outside-in corrosion of tubes in vacuum-brazed aluminum radiators, The development history, metallurgy, and field performance of long-life radiator brazing sheet are reviewed. This material utilizes the familiar sacrificial layer concept to improve corrosion resistance; however, it is unusual in that the layer is not introduced by conventional cladding means during sheet manufacture, but rather develops in situ by metallurgical transformations which occur during the brazing cycle. The sacrificial layer, about 25 mV anodic to the core alloy, increases by an order of magnitude the time-to-perforation of radiator tube sheet tested in cyclic acidified salt spray (SWAAT), which mimics the corrosion morphology observed in the field. Radiators examined after ten years of field service show excellent corrosion resistance, as predicted by SWAAT.

  7. Ten-year forecasts of water quality in Lake Michigan using a deterministic eutrophication model

    SciTech Connect

    Lesht, B.M.

    1984-03-01

    A dynamic, deterministic lake eutrophication model was used to forecast changes in Lake Michigan water quality over a ten-year simulation period. Emphasis was placed on changes in epiliminon phytoplankton biomass and in whole-lake total phosphorus concentration in response to changes in input phosphorus loads and to variations in winter conditions. Constant-condition simulations corresponding to current, increased, and reduced loads and to mild, average, and severe winters were used to establish bounds for the projected changes in water quality. Monte Carlo-type simulations were used to estimate the variance associated with the projections. Given the assumptions and limitations inherent in the modeling process, water quality in Lake Michigan is projected to improve slightly (reduced concentrations of phytoplankton and total phosphorus) over the next ten years. Year-to-year variations are significant, however, and will depend on loading and winter conditions. The variation in the projected values associated with the assumed fluctuations in loads and winter conditions is approximately 20 percent. 25 references, 20 figures, 4 tables.

  8. Scientific publications in pediatrics over the last ten years in Turkey and worldwide.

    PubMed

    Altun, Demet; Dabak, Orçun; Hacıhamdioğlu, Duygu Övünç

    2015-01-01

    In keeping with the large area of interest comprised within the field of pediatrics, the number and diversity of publications in this field has gradually increased over the last ten years in our country as well as worldwide. The objective of this paper is to offer an analysis of the status of pediatrics publications during those ten years. The publications analyzed were listed in the Thomson Reuters Web of Science and/or published in journals included in the Science Citation Index, the Science Citation Index Expanded and the Social Sciences Citation Index. All of these publications appeared in journals in which at least one pediatrics specialist published between the years 2004 and 2013. It may be seen that Turkey is in fifth place worldwide in terms of the number of studies published in these journals, with 6,134 such publications. The conclusion is that it is necessary for more Turkish studies to be multicenter, to involve international participation and to receive more citations; importance must be attached to the objective of transforming of the knowledge produced by Turkish researchers into a greater number of publications of increased quality.

  9. Idaho National Laboratory 2015-2023 Ten-Year Site Plan

    SciTech Connect

    Sheryl Morton; Elizabeth Connell; Bill Buyers; John Reisenauer; Rob Logan; Chris Ischay; Ernest Fossum; Paul Contreras; Joel Zarret; Steve Hill; Jon Tillo

    2013-09-01

    This Idaho National Laboratory (INL) Ten-Year Site Plan (TYSP) describes the strategy for accomplishing the long-term objective of sustaining the INL infrastructure to meet the Department of Energy Office of Nuclear Energy (DOE-NE) mission: to promote nuclear power as a resource capable of making major contributions in meeting the nation’s energy supply, environmental and energy security needs. This TYSP provides the strategy for INL to accomplish its mission by: (1) linking R&D mission goals to core capabilities and infrastructure requirements; (2) establishing a ten-year end-state vision for INL facility complexes; (3) identifying and prioritizing infrastructure needs and capability gaps; (4) establishing maintenance and repair strategies that allow for sustainment of mission-critical (MC) facilities; and (5) applying sustainability principles to each decision and action. The TYSP serves as the infrastructure-planning baseline for INL; and, though budget formulation documents are informed by the TYSP, it is not itself a budget document.

  10. Surgical Brain Metastases: Management and Outcome Related to Prognostic Indexes: A Critical Review of a Ten-Year Series

    PubMed Central

    Caroli, Manuela; Di Cristofori, Andrea; Lucarella, Francesca; Raneri, Fabio Angelo; Portaluri, Francesco; Gaini, Sergio Maria

    2011-01-01

    Brain metastasis are the most common neoplastic lesions of the nervous system. Many cancer patients are diagnosed on the basis of a first clinical presentation of cancer on the basis of a single or multiple brain lesions. Brain metastases are manifestations of primary disease progression and often determine a poor prognosis. Not all patients with a brain metastases undergo surgery: many are submitted to alternative or palliative treatments. Management of patients with brain metastases is still controversial, and many studies have been developed to determine which is the best therapy. Furthermore, management of patients operated for a brain metastasis is often difficult. Chemotherapy, stereotactic radiosurgery, panencephalic radiation therapy, and surgery, in combination or alone, are the means most commonly used. We report our experience in the management of a ten-year series of surgical brain metastasis and discuss our results in the preoperative and postoperative management of this complex condition. PMID:22084749

  11. Switching To Less-Expensive Blindness Drug Could Save Medicare Part B $18 Billion Over A Ten-Year Period

    PubMed Central

    Hutton, DW; Newman-Casey, PA; Tavag, M; Zacks, DN; Stein, JD

    2014-01-01

    The biologic drugs bevacizumab and ranibizumab have revolutionized treatment of diabetic macular edema and macular degeneration, leading causes of blindness. Ophthalmologic use of these drugs has increased, now accounting for roughly one-sixth of the Medicare Part B drug budget. Ranibizumab and bevacizumab have similar efficacy and potentially minor differences in adverse event rates, but at $2,023 per dose, ranibizumab costs forty times more than bevacizumab. Using modeling methods, we predict ten-year (2010–2020) population-level costs and health benefits of using bevacizumab and ranibizumab. Our results show that if all patients were treated with the less-expensive bevacizumab instead of current usage patterns, Medicare Part B, patients, and the health care system would save $18 billion, $4.6 billion, and $29 billion, respectively. Altering patterns of use with these therapies by encouraging bevacizumab use and hastening approval of biosimilar therapies would dramatically reduce spending without substantially affecting patient outcomes. PMID:24889941

  12. Favourable ten-year overall survival in a Caucasian population with high probability of hereditary breast cancer

    PubMed Central

    2010-01-01

    Background The purpose of our study was to compare differences in the prognosis of breast cancer (BC) patients at high (H) risk or intermediate slightly (IS) increased risk based on family history and those without a family history of BC, and to evaluate whether ten-year overall survival can be considered a good indicator of BRCA1 gene mutation. Methods We classified 5923 breast cancer patients registered between 1988 and 2006 at the Department of Oncology and Haematology in Modena, Italy, into one of three different risk categories according to Modena criteria. One thousand eleven patients at H and IS increased risk were tested for BRCA1/2 mutations. The overall survival (OS) and disease free survival (DFS) were the study end-points. Results Eighty BRCA1 carriers were identified. A statistically significantly better prognosis was observed for patients belonging to the H risk category with respect to women in the IS and sporadic groups (82% vs.75% vs.73%, respectively; p < 0.0001). Comparing only BRCA1 carriers with BRCA-negative and sporadic BC (77% vs.77% vs.73%, respectively; p < 0.001) an advantage in OS was seen. Conclusions Patients belonging to a population with a high probability of being BRCA1 carriers had a better prognosis than those with sporadic BC. Considering these results, women who previously had BC and had survived ten years could be selected for BRCA1 analysis among family members at high risk of hereditary BC during genetic counselling. Since only 30% of patients with a high probability of having hereditary BC have BRCA1 mutations, selecting women with a long term survival among this population could increase the rate of positive analyses, avoiding the use of expensive tests. PMID:20219108

  13. Ten-year interannual and seasonal variability of stream carbon export from a boreal peatland in northern Sweden

    NASA Astrophysics Data System (ADS)

    Leach, J.; Larsson, A.; Nilsson, M. B.; Laudon, H.

    2015-12-01

    High latitude peatlands constitute about 3% of the global land cover but store almost a third of the global soil carbon pool. The annual net ecosystem carbon balance at high latitude mires results from the balance between net ecosystem exchange, methane emission and stream discharge export. Understanding stream carbon export dynamics is needed to accurately predict how the carbon balance of peatlands will respond to climatic and environmental change. We use a ten year record (2004-2014) of streamflow and dissolved carbon (DOC, DIC, and CH4) measurements to assess interannual and seasonal variability in stream carbon export for a peatland catchment in northern Sweden. Mean annual total carbon export for the ten year period was 11.4 gC/m2, but individual years ranged between 6.1 and 17.2 gC/m2. DOC was the dominant form of carbon being exported, comprising 68% to 76% of total annual exports, and DIC contributed between 24% and 30%. CH4 made up less than 3% of total export. Stream carbon export and streamflow were highly synchronous. The majority of export (30% to 55% of annual totals) occurred during the spring snowmelt period. Exports during the summer and autumn were highly variable (1% to 45% and 9% to 53% of annual totals, respectively) and depended on the timing and magnitude of rain events. Winter periods were characterized by low streamflow conditions and associated low carbon export (0.6% to 10% of annual totals). These results highlight considerable interannual and seasonal variability of stream carbon export driven primarily by rain and snowmelt runoff events.

  14. The evolution and structure of Pegasi planets: ten years of models and still much to learn!

    NASA Astrophysics Data System (ADS)

    Guillot, T.

    2006-02-01

    Ten years after the discovery of 51 Peg b, our understanding of the evolution of "Pegasi planets" (a.k.a. "Hot Jupiters") has been shaken several times: by the discovery of the first transiting extrasolar planet, HD209458b and its large radius, the discovery of the evaporation of this planet, the measurement of the radii of several other extrasolar planets, and recently by measurements of the infrared planetary emission by the detection of the secondary eclipse for 2 Pegasides. I discuss the different theoretical explanations and models that have been proposed to explain the observations. Our understanding of Pegasides is far from complete, but great hope lies in statistical observations and characterization of transiting planets with ground based programs and the space missions COROT and Kepler.

  15. Ten years from the Antarctic Sub-millimeter Telescope and Remote Observatory

    NASA Astrophysics Data System (ADS)

    Martin, Christopher L.

    2007-08-01

    Beginning with the winter season of 1995 and for the next ten years, the Antarctic Sub-mm Telescope and Remote Observatory (AST/RO, Stark et al. 1997; Stark et al. 2001; ), a 1.7m diameter, offset Gregorian telescope located at an altitude of 2847m at the Amundsen-Scott South Pole Station collected sub-mm and Terahertz data in the 1.3mm to 200μm wavelength bands. From its location just a few hundred meters away from the geophysical South Pole, AST/RO was the first sub-mm telescope to over-winter on the polar plateau, a location uniquely suited to high quality sub-mm observations due its very low humidity, high atmospheric stability and thin troposphere (Chamberlin et al. 1997).

  16. FCC reactor product-catalyst separation: Ten years of commercial experience with closed cyclones

    SciTech Connect

    Miller, R.B.; Johnson, T.E.; Santner, C.R.; Avidan, A.A.; Johnson, D.L.

    1995-09-01

    FCC reactor closed cyclones were first commercialized ten years ago and have now been installed in over 22 FCC units worldwide. Cumulative commercial experience has shown significant yield benefits, in some cases higher than first estimated, and excellent reliability. By nearly eliminating post-riser cracking, they reduce dry gas make and produce higher yields of desirable liquid products. Trouble-free operation with closed cyclones is attributed to proper design, instrumentation, and operating procedures. The Mobil-Kellogg Closed Cyclone technology is the only design offered for license which uses the positive-pressure riser cyclone system which has proven to be least sensitive to upsets. This paper traces the development and commercialization of closed cyclones, discusses differences between competing closed cyclone designs, and documents the benefits which have been observed for Mobil-Kellogg Closed Cyclones.

  17. Idaho National Laboratory Ten-Year Site Plan Project Description Document

    SciTech Connect

    Not Listed

    2012-03-01

    This document describes the currently active and proposed infrastructure projects listed in Appendix B of the Idaho National Laboratory 2013-2022 Ten Year Site Plan (DOE/ID-11449). It was produced in accordance with Contract Data Requirements List I.06. The projects delineated in this document support infrastructure needs at INL's Research and Education Campus, Materials and Fuels Complex, Advanced Test Reactor Complex and the greater site-wide area. The projects provide critical infrastructure needed to meet current and future INL opereational and research needs. Execution of these projects will restore, rebuild, and revitalize INL's physical infrastructure; enhance program execution, and make a significant contribution toward reducing complex-wide deferred maintenance.

  18. Photoswitchable Fluorescent Proteins: Ten Years of Colorful Chemistry and Exciting Applications

    PubMed Central

    Zhou, Xin X.; Lin, Michael Z.

    2013-01-01

    Reversibly photoswitchable fluorescent proteins (RSFPs) are fluorescent proteins whose fluorescence, upon excitation at a certain wavelength, can be switched on or off by light in a reversible manner. In the last ten years, many new RSFPs have been developed and novel applications in cell imaging discovered that rely on their photoswitching properties. This review will describe research on the mechanisms of reversible photoswitching and recent applications using RSFPs. While cis-trans isomerization of the chromophore is believed to be the general mechanism for most RSFPs, structural studies reveal diversity in the details of photoswitching mechanisms, including different effects of protonation, chromophore planarity, and pocket flexibility. Applications of RSFPs include new types of live-cell superresolution imaging, tracking of protein movements and interactions, information storage, and optical control of protein activity. PMID:23876529

  19. Perspective: The first ten years of broadband chirped pulse Fourier transform microwave spectroscopy.

    PubMed

    Park, G Barratt; Field, Robert W

    2016-05-28

    Since its invention in 2006, the broadband chirped pulse Fourier transform spectrometer has transformed the field of microwave spectroscopy. The technique enables the collection of a ≥10 GHz bandwidth spectrum in a single shot of the spectrometer, which allows broadband, high-resolution microwave spectra to be acquired several orders of magnitude faster than what was previously possible. We discuss the advantages and challenges associated with the technique and look back on the first ten years of chirped pulse Fourier transform spectroscopy. In addition to enabling faster-than-ever structure determination of increasingly complex species, the technique has given rise to an assortment of entirely new classes of experiments, ranging from chiral sensing by three-wave mixing to microwave detection of multichannel reaction kinetics. However, this is only the beginning. Future generations of microwave experiments will make increasingly creative use of frequency-agile pulse sequences for the coherent manipulation and interrogation of molecular dynamics.

  20. Indolent lung opacity: Ten years follow-up of pulmonary inflammatory pseudo-tumor

    PubMed Central

    Degheili, Jad A; Kanj, Nadim A; Koubaissi, Salwa A; Nasser, Mouhamad J

    2017-01-01

    Inflammatory pseudotumor (IPT) has always been considered a diagnostic challenge. Its rarity and resemblance to other more common pathological entities imposes that neither clinical nor radiological characteristics can lead to a definitive diagnosis. The surgical excision of the lesion is the ultimate approach for accurate diagnosis and cure. Moreover the true nature of IPT, its origin as a neoplastic entity or an over-reactive inflammatory reaction to an unknown trigger, has been a long debated matter. Surgery remains the treatment of choice. IPT is mostly an indolent disease with minimal morbidity and mortality. Local invasion and metastasis predict a poor prognosis. We hereby present a unique case of pulmonary IPT that was surgically excised, but recurred contralaterally, shortly thereafter. Despite no medical or surgical treatment for ten years, the lesion has remained stable in size, with neither symptoms nor extra-pulmonary manifestations. PMID:28255550

  1. [Ten years progression-free survival obtained in a patient with mantle cell lymphoma].

    PubMed

    Wysokińska, Elwira; Kolak, Agnieszka; Starosławska, Elżbieta; Kieszko, Dariusz; Kamińska, Marzena; Surdyka, Dariusz; Mocarska, Agnieszka; Burdan, Franciszek

    2015-05-01

    Mantle cell lymphoma is a rare aggressive lymphoma derived from B cells, characterized by rapid progression and subsequent recurrence. It is considered to be an incurable disease, with exception of a certain group of patients treated with an autogenic stem cell transplantation. The mean survival time is three years, after applying the conventional regimen based on COP (cyclophosphamide, vincristine, prednisone) or CHOP chemotherapy (COP + doxorubicin). An addition of rituximab to CHOP regimen significantly prolongs progression-free survival. The present case reports ten years progression-free survival in a female patient with mantle cell lymphoma with baseline clinical stage IVB (MIPI 5), treated with nine courses of CHOP chemotherapy. Rituximab was added from 3 to 8 course. The complete clinical, radiological and histopathological response has been obtained.

  2. Clinical tolerance in large field radiotherapy--the knowledge gained over the last ten years.

    PubMed

    Gocheva, Lilia B

    2010-01-01

    Malignant disorders are still far from being successfully managed in spite of the apparent progress achieved by surgical treatment, high energy radiotherapy (RT) and chemotherapy (CHT). They keep being the second most frequent cause of lethal outcomes both in Bulgaria and in most countries of the world. One of the promising approaches to increasing the efficaciousness of treatment is development and use of methods that are in full accord with the modern requirements of a complex therapy. Over the last fifty years, large field radiation techniques, applied as systemic therapy in oncology, have been investigated and established. These techniques show the transition in oncology to using actively various variants of large field radiotherapy (LFR), the "heavy artillery" of oncoradiologic practice, as an alternative or adjunct therapy to chemotherapy (CHT). In the present paper we review the current knowledge in the field and present the clinical experience accumulated over the last ten years with respect to clinical tolerance in the major large-field radiotherapy techniques--total body irradiation, half body irradiation, whole abdominal irradiation, total and partial lymphoid irradiation. Described in detail are the contemporary knowledge about clinical and hematologic tolerance in total body irradiation as part of the myelo- and nonmyeloablative conditioning regimens as well as in half body irradiation as a systemic therapy in oncology. We also present the amassed experience in clinical tolerance in partial body irradiation in the form of whole abdominal and total or partial lymphoid irradiation. Another point worth noting based again on the experience gained over the last ten years is that for LFR we need to develop a radiotherapy technique that is designed carefully to achieve an optimal therapeutic effect that should include the disease control, good clinical tolerance and reduction of post-radiotherapy sequelae.

  3. A Vision for the Next Ten Years for Integrated Ocean Observing Data

    NASA Astrophysics Data System (ADS)

    Willis, Z. S.

    2012-12-01

    Ocean observing has come a long way since the Ocean Sciences Decadal Committee met over a decade ago. Since then, our use of the ocean and coast and their vast resources has increased substantially - with increased shipping, fishing, offshore energy development and recreational boating. That increased use has also spearheaded advances in observing systems. Cutting-edge autonomous and remotely operated vehicles scour the surface and travel to depths collecting essential biogeochemical data for better managing our marine resources. Satellites enable the global mapping of practically every physical ocean variable imaginable. A nationally-integrated coastal network of high-frequency radars lines the borders of the U.S. feeding critical navigation, response, and environmental information continuously. Federal, academic, and industry communities have joined in unique partnerships at regional, national, and global levels to address common challenges to monitoring our ocean. The 2002 Workshop, Building Consensus: Toward an Integrated and Sustained Ocean Observing System laid the framework for the current United States Integrated Ocean Observing System (U.S. IOOS). Ten years later, U.S. IOOS has moved from concept to reality, though much work remains to meet the nation's ocean observing needs. Today, new research and technologies, evolving users and user requirements, economic and funding challenges, and diverse institutional mandates all influence the future growth and implementation of U.S. IOOS. In light of this new environment, the Interagency Ocean Observation Committee (IOOC) will host the 2012 Integrated Ocean Observing System Summit in November 2012, providing a forum to develop a comprehensive ocean observing vision for the next decade, utilizing the knowledge and expertise gained by the IOOS-wide community over the past ten years. This effort to bring together ocean observing stakeholders at the regional, national, and global levels to address these challenges

  4. Ten-year development of douglas-fir and associated vegetation after different site preparation on coast range clearcuts. Forest Service research paper

    SciTech Connect

    Stein, W.I.

    1995-02-01

    Ten-years results are presented from an operational-sized, replicated experiment in the Coast Ranges of Oregon to determine the effects of six site-preparation methods on the subsequent survival and growth of Douglas-fir and associated species. Site preparation and seedling protection with plastic mesh tubing significantly enhanced tree development. Site preparation also produced large differences in frequency and cover of associated species but only minor differences in the species represented.

  5. Modeling the Office of Science ten year facilities plan: The PERI Architecture Tiger Team

    NASA Astrophysics Data System (ADS)

    de Supinski, Bronis R.; Alam, Sadaf; Bailey, David H.; Carrington, Laura; Daley, Chris; Dubey, Anshu; Gamblin, Todd; Gunter, Dan; Hovland, Paul D.; Jagode, Heike; Karavanic, Karen; Marin, Gabriel; Mellor-Crummey, John; Moore, Shirley; Norris, Boyana; Oliker, Leonid; Olschanowsky, Catherine; Roth, Philip C.; Schulz, Martin; Shende, Sameer; Snavely, Allan; Spear, Wyatt; Tikir, Mustafa; Vetter, Jeff; Worley, Pat; Wright, Nicholas

    2009-07-01

    The Performance Engineering Institute (PERI) originally proposed a tiger team activity as a mechanism to target significant effort optimizing key Office of Science applications, a model that was successfully realized with the assistance of two JOULE metric teams. However, the Office of Science requested a new focus beginning in 2008: assistance in forming its ten year facilities plan. To meet this request, PERI formed the Architecture Tiger Team, which is modeling the performance of key science applications on future architectures, with S3D, FLASH and GTC chosen as the first application targets. In this activity, we have measured the performance of these applications on current systems in order to understand their baseline performance and to ensure that our modeling activity focuses on the right versions and inputs of the applications. We have applied a variety of modeling techniques to anticipate the performance of these applications on a range of anticipated systems. While our initial findings predict that Office of Science applications will continue to perform well on future machines from major hardware vendors, we have also encountered several areas in which we must extend our modeling techniques in order to fulfill our mission accurately and completely. In addition, we anticipate that models of a wider range of applications will reveal critical differences between expected future systems, thus providing guidance for future Office of Science procurement decisions, and will enable DOE applications to exploit machines in future facilities fully.

  6. [Ten years of laparoscopic living kidney donation. From an extravagant to a routine procedure].

    PubMed

    Giessing, M; Fuller, T F; Deger, S; Roigas, J; Tüllmann, M; Liefeldt, L; Budde, K; Fischer, T; Winkelmann, B; Schnorr, D; Loening, S A

    2006-01-01

    Ten years ago the first laparoscopic living donor nephrectomy (LDN) was performed. Today, LDN is a routine operation in many US-American transplantation centers and an increasing number of centers in Europe are practicing LDN. In this article the different aspects of LDN for donor, kidney, recipient and operating surgeon are evaluated. We performed a literature research concerning LDN and the different aspects. Our own experience, as the largest LDN center in Germany, is part of the evaluation. Laparoscopic extraction of a kidney from a living donor is as safe for the donor as the open approach. At the same time, LDN offers multiple advantages like reduced pain and shorter convalescence. For the donated kidney and the recipient no disadvantages occur from the laparoscopic technique, as long as special intra- and perioperative demands are met. For the operating surgeon multiple developments have expanded the technical armentarium. LDN is safe for donor, recipient and kidney. Central issue of an optimal LDN is sufficient experience with laparoscopic urological techniques.

  7. Persistence of native and exotic plants ten years after prairie reconstruction data set

    USGS Publications Warehouse

    Larson, Diane L.; Bright, J. B.; Drobney, Pauline; Larson, Jennifer L.; Vacek, Sara

    2016-01-01

    These data sets consist of data collected during 2005-2007, 2010, and 2015 at Neal Smith NWR (IA) and Fergus Falls, Litchfield, and Morris Wetland Management Districts (MN) that were used in the analysis in support of the article titled "Integrity of tallgrass prairie reconstructions ten years after planting: native plant persistence and exotic weed resistance," which has been submitted to the journal Restoration Ecology. The primary goal of this study was to understand what influence early reconstruction practices have on long-term outcomes. Twelve replicates of three planting methods (dormant-season broadcast, growing-season broadcast, and growing-season drill) and three seed mix richness levels (10, 20 or 34 species), fully crossed in a completely randomized design were planted in 2005 on nine former agricultural fields. Cover by species was estimated in 2005-2007, 2010 and 2015, and richness data for treatment plots was determined in 2007, 2010, and 2015. Data from Minnesota and Iowa sites were analyzed separately, and are housed in separate files.

  8. Ten Years of Proteomics in Bladder Cancer: Progress and Future Directions

    PubMed Central

    Frantzi, Maria; Vlahou, Antonia

    2017-01-01

    Research efforts targeting the identification of bladder cancer biomarkers have been extensive during the past decade. Investigations have been performed at the genome, transcriptome, proteome, and metabolome levels and outputs have started appearing including the sketching of disease molecular subtypes. Proteins are directly linked to cell phenotype hence they accumulate special interest as both biomarkers and therapeutic targets. Multiple technical challenges exist, of the main, being the protein concentration vast dynamic range and presence of proteins in modified forms. The scope of this review is to summarize the contribution of proteomics research in this quest of bladder cancer biomarkers. To obtain an unbiased and comprehensive overview, the scientific literature was searched for manuscripts describing proteomic studies on urothelial cancer from the last ten years and those including independent verification studies in urine, tissue and blood are briefly presented. General observations include: a) in most cases, suboptimal experimental design including healthy controls in biomarker discovery and frequently biomarker verification, is followed; b) variability in protein findings between studies can be observed, to some extent reflecting complexity of experimental approaches and proteome itself; c) consistently reported biomarkers include mainly plasma proteins and d) compilation of protein markers into diagnostic panels appears the most promising way forward. Two main avenues of research can now be foreseen: targeting integration of the existing disparate data with proteomic findings being placed in the context of existing knowledge on bladder cancer subtypes and in parallel, accumulation of clinical samples to support proper validation studies of promising marker combinations. PMID:28149930

  9. Analyzing the Study of Using Acupuncture in Delivery in the Past Ten Years in China

    PubMed Central

    Chen, Yingru; Zhang, Xuekai; Fang, Yigong; Yang, Jinsheng

    2014-01-01

    The use of acupuncture in inducing delivery has a long history in China. With progress over time, it has been applied in many aspects. For further study of acupuncture in delivery, this paper analyzed the papers using acupuncture in delivery in the past ten years in mainland China. 87 literatures were picked out by searching relevant electronic databases and bibliographies of relevant journals. The analysis showed randomized controlled trials that were the major type of research, while preclinical researches and literature reviews only account for around ten percent, respectively. Clinical researches indicated that acupuncture can relieve labor pain, promote maternal uterine contraction, shorten birth process, and treat postpartum disorders. Preclinical researches found that acupuncture can adjust certain hormones and improve uterus contraction of late-stage pregnant rats. However, due to lack of large multicenter randomized controlled clinical trials, standardized evaluations of clinical effects in clinical researches and detailed mechanism study in preclinical researches and unequivocal conclusions about the effectiveness, efficacy, and mechanisms of acupuncture in this field cannot be obtained from those researches yet. Further clinical and preclinical studies about the use of acupuncture in delivery with improved methodology is still needed. PMID:24688593

  10. The Register of Antarctic Marine Species (RAMS): a ten-year appraisal

    PubMed Central

    Jossart, Quentin; Moreau, Camille; Agüera, Antonio; Broyer, Claude De; Danis, Bruno

    2015-01-01

    Abstract The Register of Antarctic Marine Species (RAMS) is a marine species database that manages an authoritative taxonomic list of species occurring in the Southern Ocean. RAMS links with several other initiatives managing biogeographic or genomics information. The current paper aims to briefly present RAMS and provides an updated snapshot of its contents, in the form of a DarwinCore checklist (available through http://ipt.biodiversity.aq/resource.do?r=rams) and illustrative barplots. Moreover, this article presents a ten year appraisal (since the creation of RAMS). This appraisal first focuses on RAMS bibliometrics. We observed that RAMS was cited (Google Scholar) in 50 distinct publications among which 32 were peer-reviewed in 18 different journals. Three journals (Antarctic Science, Polar Biology, ZooKeys) represent almost 40% of these peer-review publications. The second appraisal focuses on the evolution of new RAMS records. We observed an important decrease in data additions since 2011. As a case study, we focused on an original dataset for a specific group (Asteroidea, Echinodermata). It appears that around one hundred species of asteroids are lacking in RAMS despite the relatively high availability of these data. This suggests that the users’ community (or collaborative projects such as AquaRES) could be helpful in order to maintain the RAMS database over the long term. PMID:26478709

  11. [Evaluation of Uruguay's antismoking campaign: progress and challenges at ten years].

    PubMed

    Triunfo, Patricia; Harris, Jeffrey; Balsa, Ana

    2016-10-01

    In 2005, shortly after ratifying the Framework Convention on Tobacco Control (FCTC), Uruguay began an ambitious tobacco control campaign that brought the country to the global forefront in the fight against smoking. The wide range of measures implemented in a relatively short period and the rigorousness with which policies were implemented and enforced have few precedents, even in the most developed countries. This paper presents a synthesis and update of several papers by the authors that evaluate different aspects of the campaign ten years following ratification of the FCTC. In particular, these research studies highlight the campaign's aggregate impact on the drop in prevalence of current tobacco consumption in adult and youth populations, and on decisions by pregnant women to quit smoking (1, 2), as well as the relative impact of tax policies in relation to non-price tobacco control measures. The analyses are based on observational studies (at the population or individual level) that use external (Argentina and Chile) and internal (nonsmokers) control groups. Pending challenges in the design of antismoking policies are also discussed.

  12. Naive (commonsense) geography and geobrowser usability after ten years of Google Earth

    NASA Astrophysics Data System (ADS)

    Hamerlinck, J. D.

    2016-04-01

    In 1995, the concept of ‘naive geography’ was formally introduced as an area of cognitive geographic information science representing ‘the body of knowledge that people have about the surrounding geographic world’ and reflecting ‘the way people think and reason about geographic space and time, both consciously and subconsciously’. The need to incorporate such commonsense knowledge and reasoning into design of geospatial technologies was identified but faced challenges in formalizing these relationships and processes in software implementation. Ten years later, the Google Earth geobrowser was released, marking the beginning of a new era of open access to, and application of, geographic data and information in society. Fast-forward to today, and the opportunity presents itself to take stock of twenty years of naive geography and a decade of the ubiquitous virtual globe. This paper introduces an ongoing research effort to explore the integration of naive (or commonsense) geography concepts in the Google Earth geobrowser virtual globe and their possible impact on Google Earth's usability, utility, and usefulness. A multi-phase methodology is described, combining usability reviews and usability testing with use-case scenarios involving the U.S.-Canadian Yellowstone to Yukon Initiative. Initial progress on a usability review combining cognitive walkthroughs and heuristics evaluation is presented.

  13. Modeling the Office of Science Ten Year Facilities Plan: The PERI Architecture Tiger Team

    SciTech Connect

    de Supinski, Bronis R.; Alam, Sadaf; Bailey, David H.; Carrington, Laura; Daley, Chris; Dubey, Anshu; Gamblin, Todd; Gunter, Dan; Hovland, Paul D.; Jagode, Heike; Karavanic, Karen; Marin, Gabriel; Mellor-Crummey, John; Moore, Shirley; Norris, Boyana; Oliker, Leonid; Olschanowsky, Catherine; Roth, Philip C.; Schulz, Martin; Shende, Sameer; Snavely, Allan; Spear, Wyatt; Tikir, Mustafa; Vetter, Jeff; Worley, Pat; Wright, Nicholas

    2009-06-26

    The Performance Engineering Institute (PERI) originally proposed a tiger team activity as a mechanism to target significant effort optimizing key Office of Science applications, a model that was successfully realized with the assistance of two JOULE metric teams. However, the Office of Science requested a new focus beginning in 2008: assistance in forming its ten year facilities plan. To meet this request, PERI formed the Architecture Tiger Team, which is modeling the performance of key science applications on future architectures, with S3D, FLASH and GTC chosen as the first application targets. In this activity, we have measured the performance of these applications on current systems in order to understand their baseline performance and to ensure that our modeling activity focuses on the right versions and inputs of the applications. We have applied a variety of modeling techniques to anticipate the performance of these applications on a range of anticipated systems. While our initial findings predict that Office of Science applications will continue to perform well on future machines from major hardware vendors, we have also encountered several areas in which we must extend our modeling techniques in order to fulfill our mission accurately and completely. In addition, we anticipate that models of a wider range of applications will reveal critical differences between expected future systems, thus providing guidance for future Office of Science procurement decisions, and will enable DOE applications to exploit machines in future facilities fully.

  14. Modeling the Office of Science Ten Year Facilities Plan: The PERI Architecture Team

    SciTech Connect

    de Supinski, Bronis R.; Alam, Sadaf R; Bailey, David; Carrington, Laura; Daley, Christopher; Dubey, Anshu; Gamblin, Todd; Gunter, Dan; Hovland, Paul; Jagode, Heike; Karavanic, Karen; Marin, Gabriel; Mellor-Crummey, John; Moore, Shirley; Norris, Boyana; Oliker, Leonid; Olschanowsky, Cathy; Roth, Philip C; Schulz, Martin; Shende, Sameer; Snavely, Allan; Spea, Wyatt; Tikir, Mustafa; Vetter, Jeffrey S; Worley, Patrick H; Wright, Nicholas

    2009-01-01

    The Performance Engineering Institute (PERI) originally proposed a tiger team activity as a mechanism to target significant effort optimizing key Office of Science applications, a model that was successfully realized with the assistance of two JOULE metric teams. However, the Office of Science requested a new focus beginning in 2008: assistance in forming its ten year facilities plan. To meet this request, PERI formed the Architecture Tiger Team, which is modeling the performance of key science applications on future architectures, with S3D, FLASH and GTC chosen as the first application targets. In this activity, we have measured the performance of these applications on current systems in order to understand their baseline performance and to ensure that our modeling activity focuses on the right versions and inputs of the applications. We have applied a variety of modeling techniques to anticipate the performance of these applications on a range of anticipated systems. While our initial findings predict that Office of Science applications will continue to perform well on future machines from major hardware vendors, we have also encountered several areas in which we must extend our modeling techniques in order to fulfilll our mission accurately and completely. In addition, we anticipate that models of a wider range of applications will reveal critical differences between expected future systems, thus providing guidance for future Office of Science procurement decisions, and will enable DOE applications to exploit machines in future facilities fully.

  15. Modeling the Office of Science Ten Year FacilitiesPlan: The PERI Architecture Tiger Team

    SciTech Connect

    de Supinski, B R; Alam, S R; Bailey, D H; Carrington, L; Daley, C

    2009-05-27

    The Performance Engineering Institute (PERI) originally proposed a tiger team activity as a mechanism to target significant effort to the optimization of key Office of Science applications, a model that was successfully realized with the assistance of two JOULE metric teams. However, the Office of Science requested a new focus beginning in 2008: assistance in forming its ten year facilities plan. To meet this request, PERI formed the Architecture Tiger Team, which is modeling the performance of key science applications on future architectures, with S3D, FLASH and GTC chosen as the first application targets. In this activity, we have measured the performance of these applications on current systems in order to understand their baseline performance and to ensure that our modeling activity focuses on the right versions and inputs of the applications. We have applied a variety of modeling techniques to anticipate the performance of these applications on a range of anticipated systems. While our initial findings predict that Office of Science applications will continue to perform well on future machines from major hardware vendors, we have also encountered several areas in which we must extend our modeling techniques in order to fulfill our mission accurately and completely. In addition, we anticipate that models of a wider range of applications will reveal critical differences between expected future systems, thus providing guidance for future Office of Science procurement decisions, and will enable DOE applications to exploit machines in future facilities fully.

  16. Ten years after "Worrying trends in econophysics": developments and current challenges

    NASA Astrophysics Data System (ADS)

    Ormerod, Paul

    2016-12-01

    Econophysics has made a number of important additions to scientific knowledge. Yet it continues to lack influence with both economists and policy makers. Ten years ago, I and three other economists sympathetic to econophysics wrote a paper on worrying trends within the discipline. For example, its lack of awareness of the economics literature, and shortfalls in the use of statistical analysis. These continue to be obstacles to wider acceptance by economists. Like all agents, policy makers respond to incentives, and economists understand this very well. Much of the econophysics community appears to think that simply doing good science is sufficient to have the work recognised, rather than relating to the motivations and incentives of policy makers. Nevertheless, econophysics now has three major opportunities to advance knowledge in areas where policy makers perceive weaknesses in what they are presented with by economists. All can benefit from the analysis of Big Data. The first is a core model of agent behaviour which is more relevant to cyber society than the rational agent model of economics. Second, extending our understanding of the business cycle, primarily by incorporating the importance of networks into models. Third, devising proper measures of output in cyber society.

  17. Reflection on the Process of Open Sourcing Software Based on Ten Years of Development of RAPID

    NASA Astrophysics Data System (ADS)

    David, C. H.; Famiglietti, J. S.; Yang, Z. L.; Habets, F.; Maidment, D.

    2015-12-01

    As the number and size of geoscience datasets persist in their constant rise, geoscientists increasingly express their yearning for further sharing of their data and software, and for facilitation of the associated academic credits. We present here our experience based on the open source development of an Earth System Model focusing on the propagation of water flow waves in large river networks: the Routing Application for Parallel computatIon of Discharge (RAPID). Since inception of RAPID ten years ago in January 2006, the community of its users has grown slowly but steadily, and now includes researchers in industry, academia, and government organizations. This growth of the RAPID users community can be explained - at least in part - by its open availability. However, despite an increasing support for open science (software and data), the mechanics of sharing still remain mysterious to many geoscientists… as they were for the authors. The purpose of this presentation is therefore to shed light on the steps involved in opening software and data based on a decade of experience related to the development and release of an Earth System Model. Three distinct steps of open sourcing are highlighted here: opening, exposing, and automatic testing. Each one of these steps is presented as an independent and tractable increment at various stages of development that is justified based on the size of the users community. Topics covered include software and data licenses, code and data repositories, unit testing, and continuous integration.

  18. Highlighting ten years of physics education research in the upper division

    NASA Astrophysics Data System (ADS)

    Ambrose, Bradley

    2015-04-01

    The field of Physics Education Research (PER) has for over thirty years provided insights into student thinking and guided the development and assessment of reformed teaching strategies and practices in introductory physics courses. In the last decade or so, researchers have expanded the domain of such investigations to upper-division courses where undergraduate majors study more advanced content and begin to see themselves as future physicists. The upcoming Focused Collection on Upper Division PER brings together work from researchers active in these new frontiers of PER. In this presentation we provide an overview of the studies in this collection, which offer to the PER and greater physics education communities: new insights about the thinking, behavior, and beliefs of students in the upper division; new tools to innovate instruction, assess student learning, and evaluate teaching effectiveness; and groundbreaking studies of identity development and ``thinking like a physicist'' among physics majors. In this session we also recognize the ten-year anniversary of Physical Review Special Topics: Physics Education Research, an occasion that we will celebrate with an informal reception immediately following the conclusion of this invited session.

  19. 1994-2004 : Ten years of European effort for education in Seismology

    NASA Astrophysics Data System (ADS)

    Virieux, J.; Zollo, A.; Lomax, A.; Berenguer, J.; Laj, C.; Bobbio, A.

    2004-12-01

    Following trends of the pioneer PEPP project in USA, an European group has investigated since 1994 how to promote physics and earth sciences and, more specifically, how to educate scientifically and socially young generations to environmental hazards. Seismology has been selected as the vehicle for a prototypical ten-years experience of teaching and learning sciences in European high schools accounting for the specificity and differencies of educational systems in each country. This general purpose has required competences and strong interactions of both teachers, researchers and high school students. Over ten years of continuous activities, these people have found that the target was very ambitious and that both high-tech efforts as well as very focused teaching procedures must be set on. Dedicated instruments were developped in two years through interactions between researchers,teachers and students in order to fit both the scientific quality but also pedagogical features and were installed in different parts of Europe. The sequence of Colfiorito Earthquakes in September-October 1997 was the first data collected simultaneously in different European schools. Since then, more thant 50 stations have been deployed over Europe and data have been made available for education purposes. Data from these seismic stations have been used as the back-bone for interactions between students/pupils, teachers and researchers leading to the development of dedicated teaching and learning materials as software tools for data analysis, simple experimentations and so on. The framework for such an European initiative has been provided by Italian and French national funds and put together under the banner of the so-called EDUSEIS projet. This EDUcational SEISmological European Network (http://www.eduseis.org/) has shown that indeed environmental education is possible with its typical feature of long-term efforts. Funding through Europe will certainly increase the cohesion of this

  20. Ten years of studies on Maryland's inner Continental Margin and coastal bays

    USGS Publications Warehouse

    Kerhin, R.T.; Conkwright, R.; Wells, D.

    1999-01-01

    During the past ten years of the Association of American State Geologists-Mineral Management Service Continental Margins Program, the Maryland Geological Survey investigated the sedimentological, paleontological, stratigraphical and geophysical character of Maryland's inner continental shelf. Based on seismic records and sedimentological analyses completed during the first four years, a late Quaternary stratigraphic model was developed. Five distinct stratigraphic units were identified and described on the Maryland inner shelf. These units represent late Pleistocene interglacial deposits, the oldest of which corresponds to pre-Illinoian (oxygen-isotope stages 7 and/or 9) transgressive shelf sands. Overlying the Q1 unit, the Q2 unit is a 6-meter thick mud sequence of oxygen-isotope stage 5 (128-75 ka) age. Units Q3 and Q4 representing fluvial and leading edge estuarine deposits (oxygen-isotope stages 4, 3 and 2) filled numerous paleochannels that were incised into units Q2 and Q1. Modern trailing-edge transgressive shelf shoals (Unit Q5) discontinuously cap the sequence. The 5th and 6th years studies reported on the economic minerals of surficial and cored sediments. Vibracores collected off the Maryland's shelf during previous studies were analyzed for mineral types and abundances, weight percent of general size fractions, and heavy mineral (HM) content. Mineralogic maturity indices were compiled to correlate the THM and economic heavy minerals (EHM) abundances with position offshore, sediment type, and the indices themselves. For the 7th year, the Maryland Geological Survey re-examined geophysical records and lithological data originally collected by the Army Corps of Engineers to locate and assess beach fill borrow areas for the Ocean City Beach Replenishment Project. Data from 163 vibracores and over 300 kilometers of high-resolution seismic profile records collected off Ocean City, Maryland, supported the stratigraphic model developed by MGS during the first

  1. Clinical characteristics of renal cancer in Malaysia : a ten year review.

    PubMed

    Singam, Praveen; Ho, Christopher; Hong, Goh Eng; Mohd, Azrif; Tamil, Azmi Md; Cheok, Lee Boon; Zainuddin, Zulkifli

    2010-01-01

    Renal cancer is rare and its incidence is 1.9 per 100,000 in the Malaysian population, which consists of three major ethnic groups (Malay, Chinese and Indians). A retrospective study was her conducted to identify clinical characteristics and ethnic background influences on presentation. The study included all renal cancer patients from a single medical institution over ten years, with a total of 75 cases. Seventy-three patients underwent surgery while 2 received only radiotherapy or chemotherapy. The male to female ratio was 2.75:1. Incidence was equal among the Malay (49.3%) and Chinese ethnic groups (45.3%). Mean age of patients were 57.1 (18-93) years old. There were 26 (37.4%) patients with Stage I disease, 14 (18.7%) at Stage II, 23 (30.7%) at Stage III and 12 (16%) at Stage IV. The Chinese race presented at mean older age (p= 0.02) and later stage of disease (p= 0.046). Patients above 40 years old had more advanced stage disease (p= 0.023). Tumour histology were clear cell (72%), urothelial cell (13.3%), sarcomatoid cell and nephroblastoma each contributed 2.7%. The mean tumour size was 8.1 (2-20) cm. There was substantial agreement between the pre and post operative staging (kappa 0.691). In conclusion we observed significant influences of age and race in the clinical presentation of renal cancer in our institution based population. There was larger male to female ratio and mean tumour size as compared to previous epidemiology studies.

  2. Switching to less expensive blindness drug could save medicare part B $18 billion over a ten-year period.

    PubMed

    Hutton, David; Newman-Casey, Paula Anne; Tavag, Mrinalini; Zacks, David; Stein, Joshua

    2014-06-01

    The biologic drugs bevacizumab and ranibizumab have revolutionized treatment of diabetic macular edema and neovascular age-related macular degeneration, leading causes of blindness. Ophthalmologic use of these drugs has increased and now accounts for roughly one-sixth of the Medicare Part B drug budget. The two drugs have similar efficacy and potentially minor differences in adverse-event rates; however, at $2,023 per dose, ranibizumab costs forty times more than bevacizumab. Using modeling methods, we predict ten-year (2010-20) population-level costs and health benefits of using bevacizumab and ranibizumab. Our results show that if all patients were treated with the less expensive bevacizumab instead of current usage patterns, savings would amount to $18 billion for Medicare Part B and nearly $5 billion for patients. With an additional $6 billion savings in other health care expenses, the total savings would be almost $29 billion. Altering patterns of use with these therapies by encouraging bevacizumab use and hastening approval of biosimilar therapies would dramatically reduce spending without substantially affecting patient outcomes.

  3. Saturn’s Tropospheric Temperatures and Para-Hydrogen Distribution from Ten Years of Cassini Observations

    NASA Astrophysics Data System (ADS)

    Fletcher, Leigh N.; Irwin, Patrick G.; Sinclair, James; Giles, Rohini; Barstow, Joanna; Achterberg, Richard K.; Orton, Glenn S.

    2014-11-01

    Cassini/CIRS observations of Saturn’s 10-1400 cm-1 spectrum have been inverted to construct a global record of tropospheric temperature and para-hydrogen variability over the ten-year span of the Cassini mission. The data record the slow reversal of seasonal asymmetries in tropospheric conditions from northern winter (2004, Ls=293), through northern spring equinox (2009, Ls=0) to the present day (2014, Ls=60). Mid-latitude tropospheric temperatures have cooled by approximately 4-6 K in the south and warmed by 2-4 K in the north, with the seasonal contrast decreasing with depth. CIRS detected the north polar minimum 100-mbar temperatures 6-8 years after winter solstice, whereas the south polar maximum occurred 1-2 years after summer solstice, consistent with the lag times predicted by radiative equilibrium models. Warm polar cyclones and the northern hexagon persist throughout the mission, suggesting that they are permanent features of Saturn’s tropospheric circulation. The 200-mbar thermal enhancement (“knee”) that was strongest in the summer but weak or absent in winter in 2004-2006 (Fletcher et al., 2007, Icarus 189, p.457-478) has now shifted northward and is present globally in 2014, suggestive of radiative heating in Saturn’s tropospheric haze layer. Saturn’s para-H2 fraction, which serves as a tracer of both tropospheric mixing and the efficiency of re-equilibration between the ortho- and para-hydrogen states, is slowly altering: super-equilibrium conditions (para-H2 fraction exceeding equilibrium expectations and suggestive of subsiding airmasses) that dominated the southern summer hemisphere are now weakening, whereas the sub-equilibrium conditions (suggestive of uplift) of the northern winter are being replaced by equilibrium or super-equilibrium conditions in spring. The thermal ‘knee’ and the para-H2 distribution are tracking both the increased spring illumination and the increasing tropospheric haze opacity of the springtime hemisphere

  4. Creative Climate: A global ten-year communications, research and learning project about environmental change

    NASA Astrophysics Data System (ADS)

    Brandon, M. A.; Smith, J.

    2010-12-01

    The next ten years have been described by influential science and policy figures as ‘the most important in human history’. Many believe that the actions taken will decide whether we catastrophically change the atmosphere and eradicate our fellow species or find an alternative, less-damaging development path. But communications and public engagement initiatives have tended to focus on near term impacts or debates - whether they emphasise hazards, or trumpet ‘solutions’. There are signs of diminishing returns on communications and public engagement efforts, and serious obstacles to engaging around 40% of publics in e.g. the US and the UK. The Creative Climate web project takes a new approach, inviting people to see humanity’s intellectual and practical journey with these issues as an inspiring, dynamic and unfolding story. We are inviting people to join us in building a huge living archive of experiences and ideas that respond to these issues. The website will collect thoughts and stories from doorstep to workplace, from lab to garden; from international conference to community meeting - from all over the world. The body of diaries lie at the core of the project, but these are supplemented by the offer of free online learning resources and broadcast-quality audio and video materials. The project is experimental in terms of its scope, its approach to environmental communications and debate and in its use of media. It works with formal partners, including the BBC, yet also makes the most of the opportunities for user generated content to create a rich multimedia resource that can support research, learning and engagement. The design of the project is informed by environmental social science and communications research, and by an awareness of the unfolding potential of Internet based communications to support social change. It is also intended that the Creative Climate platform will develop so as to serve researchers by offering an open resource of qualitative

  5. Offsite source recovery project - ten years of sealed source recovery and disposal

    SciTech Connect

    Whitworth, Julia Rose; Pearson, Mike; Witkowski, Ioana; Wald - Hopkins, Mark; Cuthbertson, A

    2010-01-01

    The Global Threat Reduction Initiative's (GTRI) Offsite Source Recovery Project (OSRP) has been recovering excess and unwanted radioactive sealed sources for ten years. In January 2009, GTRI announced that the project had recovered 20,000 sealed radioactive sources (this number has since increased to more than 23,000). This project grew out of early efforts at Los Alamos National Laboratory (LANL) to recover and disposition excess Plutonium-239 (Pu-239) sealed sources that were distributed in the 1960s and 1970s under the Atoms for Peace Program. Decades later, these sources began to exceed their special form certifications or fall out of regular use. As OSRP has collected and stored sealed sources, initially using 'No Path Forward' waste exemptions for storage within the Department of Energy (DOE) complex, it has consistently worked to create disposal pathways for the material it has recovered. The project was initially restricted to recovering sealed sources that would meet the definition of Greater-than-Class-C (GTCC) low-level radioactive waste, assisting DOE in meeting its obligations under the Low-level Radioactive Waste Policy Act Amendments (PL 99-240) to provide disposal for this type of waste. After being transferred from DOE-Environmental Management (EM) to the U.S. National Nuclear Security Administration (NNSA) to be part of GTRI, OSRP's mission was expanded to include not only material that would be classified as GTCC when it became waste, but also any other materials that might constitute a 'national security consideration.' It was recognized at the time that the GTCC category was a waste designation having to do with environmental consequence, rather than the threat posed by deliberate or accidental misuse. The project faces barriers to recovery in many areas, but disposal continues to be one of the more difficult to overcome. This paper discusses OSRP's disposal efforts over its 10-year history. For sources meeting the DOE definition of

  6. [Good agricultural practice (GAP) of Chinese materia medica (CMM) for ten years: achievements, problems and proposals].

    PubMed

    Guo, Lan-Ping; Zhang, Yan; Zhu, Shou-Dong; Wang, Gui-Hua; Wang, Xiu; Zhang, Xiao-Bo; Chen, Mei-Lan; He, Ya-Li; Han, Bang-Xing; Chen, Nai-Fu; Huang, Lu-Qi

    2014-04-01

    This paper aims to summarize the achievements during the implementation process of good agricultural practice (GAP) in Chinese Materia Medica (CMM), and on basis of analyzing the existing problems of GAP, to propose further implementation of GAP in TCM growing. Since the launch of GAP in CMM growing ten years ago, it has acquired great achievements, including: (1) The promulgation of a series of measures for the administration of the GAP approval in the CMM growing; (2) The expanded planting area of CMM; (3) The increased awareness of standardized CMM growing among farmers and enterprises; (4) The establishment of GAP implementation bases for CMM growing; (5) The improvement of theory and methodology for CMM growing; (6) The development of a large group of experts and scholars in GAP approval for CMM production. The problems existing in the production include: (1) A deep understanding of GAP and its certification is still needed; (2) The distribution of the certification base is not reasonable; (3) The geo-economics effect and the backward farming practices are thought to be the bottlenecks in the standardization of CMM growing and the scale production of CMM; (4) Low comparative effectiveness limits the development of the GAP; (5) The base of breeding improved variety is blank; (6) The immature of the cultivation technique lead to the risk of production process; (7) The degradation of soil microbial and the continuous cropping obstacle restrict the sustainable development of the GAP base. To further promote the health and orderly GAP in the CMM growing, the authors propose: (1) To change the mode of production; (2) To establish a sound standard system so as to ensure quality products for fair prices; (3) To fully consider the geo-economic culture and vigorously promote the definite cultivating of traditional Chinese medicinal materials; (4) To strengthen the transformation and generalization of basic researches and achievements, in order to provide technical

  7. Home Environment and School Performance: A Ten-Year Follow-up and Examination of Three Models of Environmental Action.

    ERIC Educational Resources Information Center

    Bradley, Robert H.; And Others

    1988-01-01

    Examines home environments of children aged ten and eleven when they were six months and two years old. Significant correlations were observed between the home environments at two and ten years, children's achievement test scores, and classroom behavior. Home environment at six months was related to a minimal number of classroom behaviors. (RJC)

  8. A Decade of Development: The Best of Ten Years. An Anniversary Publication of Selected Papers. Adult Student Personnel Association, Inc.

    ERIC Educational Resources Information Center

    Clifford, Earle W., Ed.; And Others

    "The Best of Ten Years," a publication of the Tenth Annual Conference for the Adult Student Personnel Association, Inc. (ASPA), contains prophesies for the future in addition to a chronicle of concerns of the decade. Articles included are: Financial Aid for Evening Students (Sol Jacobson); The Programming and Counseling of Adult Transfer Students…

  9. Ten Years of Youth Programs at the American Museum of Natural History: An Independent Perspective and Lessons Learned

    ERIC Educational Resources Information Center

    Carroll, Becky

    2008-01-01

    In this report, the author shares her perspective on ten years of science-rich programming for high school youth at the American Museum of Natural History. This report includes: (1) A discussion of the theory of action and the rationale that underlies the AMNH youth programs; (2) A description of three of the programs that have been offered and…

  10. Russia: despite legislative and procedural barriers, HIV-positive woman fights for custody of ten-year-old brother.

    PubMed

    Utyasheva, Leah

    2009-12-01

    Svetlana Izambaeva, a well-known HIV-activist and educator in Russia, is seeking to obtain custody of her ten-year-old brother, Sasha. After their mother died, regional official refused Izambaeva custody because of her HIV-positive status. Consequently, the local child custody agency (organ opeki) decided to give Sasha to a foster family.

  11. Organisation and Management of a Complete Bachelor Degree Offered Online at the University of Milan for Ten Years

    ERIC Educational Resources Information Center

    Milani, Manuela; Papini, Sabrina; Scaccia, Daniela; Scarabottolo, Nello

    2014-01-01

    This paper is aimed at presenting some reflections on organisation and management of SSRI online: an e-learning initiative started at the University of Milan (Italy) in the academic year 2004/05 and offered to students over the last ten years. The initiative consisted in implementing the online version of an already existing three-year bachelor…

  12. A Study in Critical Listening Using Eight to Ten Year Olds in an Analysis of Commercial Propaganda Emanating from Television.

    ERIC Educational Resources Information Center

    Cook, Jimmie Ellis

    Selected eight to ten year old Maryland children were used in this study measuring the effect of lessons in becoming aware of propaganda employed by commercial advertisers in television programs. Sixteen 45-minute lessons directed to the propaganda techniques of Band Wagon, Card Stacking, Glittering Generalities, Name Calling, Plain Folks,…

  13. 78 FR 46861 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Greeley AGENCY: Environmental Protection Agency...

  14. 78 FR 56185 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... From the Federal Register Online via the Government Publishing Office ] ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Fort Collins AGENCY: Environmental Protection...

  15. 78 FR 46816 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Greeley AGENCY: Environmental Protection Agency...

  16. 78 FR 41342 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-10

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Ca on City AGENCY: Environmental Protection Agency...

  17. 78 FR 46552 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year Carbon Monoxide Maintenance Plan for Colorado Springs AGENCY: Environmental...

  18. 78 FR 71550 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Telluride AGENCY: Environmental Protection Agency...

  19. 78 FR 57573 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year PM 10 Maintenance Plan for Aspen AGENCY: Environmental Protection Agency (EPA)....

  20. Ten-Year Monitored Natural Recovery of Lead-Contaminated Mine Tailing in Klity Creek, Kanchanaburi Province, Thailand

    PubMed Central

    Phenrat, Tanapon; Otwong, Ashijya; Chantharit, Aphichart; Lowry, Gregory V.

    2016-01-01

    Background: Klity Creek has become Thailand’s first official remediation ordered by the court in 2013, 15 years after the spill of lead (Pb)-contaminated mine tailing into the creek. The Pollution Control Department (PCD) decided to restore the creek through monitored natural recovery (MNR) since 2006 but has not been successful. Interestingly, the most recent remediation plan in 2015 will still apply MNR to five out of the seven portions of the creek, despite no scientific feasibility evaluation of using MNR to restore the creek. Objective: This study qualitatively and quantitatively evaluated the feasibility of using MNR to clean up the creek in order to protect the Klity children from excess Pb exposure. Methods: We analyzed the physical and chemical transformation of Pb contaminated sediment in the creek and developed a remedial action goal and cleanup level using the Integrated Exposure Uptake Biokinetic model (IEUBK). We empirically determined the natural recovery (NR) potentials and rates using 10 years of data monitoring the water and sediment samples from eight monitoring stations (KC1 to KC8). Results: Klity Creek has NR potential for water except at KC2, which is closest to the spill and the other improperly managed Pb sources. However, the creek has no NR potential for sediment except at the KC8 location (NR rate = 11.1 ± 3.0 × 10–3 month–1) farthest from the spill. Conclusion: The MNR method is not suitable to use as the sole remedial approach for Klity Creek (KC2 to KC7). Although MNR is applicable at KC8, it may require up to 377 ± 76 years to restore the sediment to the background Pb concentration. Citation: Phenrat T, Otwong A, Chantharit A, Lowry GV. 2016. Ten-year monitored natural recovery of lead-contaminated mine tailing in Klity Creek, Kanchanaburi Province, Thailand. Environ Health Perspect 124:1511–1520; http://dx.doi.org/10.1289/EHP215 PMID:27157823

  1. A ten-year global record of absorbing aerosols above clouds from OMI's near-UV observations

    NASA Astrophysics Data System (ADS)

    Jethva, Hiren; Torrres, Omar; Ahn, Changwoo

    2016-05-01

    Aerosol-cloud interaction continues to be one of the leading uncertain components of climate models, primarily due to the lack of an adequate knowledge of the complex microphysical and radiative processes associated with the aerosolcloud system. The situations when aerosols and clouds are found in the same atmospheric column, for instance, when light-absorbing aerosols such as biomass burning generated carbonaceous particles or wind-blown dust overlay low-level cloud decks, are commonly found over several regional of the world. Contrary to the cloud-free scenario over dark surface, for which aerosols are known to produce a net cooling effect (negative radiative forcing) on climate, the overlapping situation of absorbing aerosols over cloud can potentially exert a significant level of atmospheric absorption and produces a positive radiative forcing at top-of-atmosphere. The magnitude of direct radiative effects of aerosols above cloud depends directly on the aerosol loading, microphysical-optical properties of the aerosol layer and the underlying cloud deck, and geometric cloud fraction. We help in addressing this problem by introducing a novel product of optical depth of absorbing aerosols above clouds retrieved from near-UV observations made by the Ozone Monitoring Instrument (OMI) on board NASA's Aura platform. The presence of absorbing aerosols above cloud reduces the upwelling radiation reflected by cloud and produces a strong `color ratio' effect in the near-UV region, which can be unambiguously detected in the OMI measurements. Physically based on this effect, the OMACA algorithm retrieves the optical depths of aerosols and clouds simultaneously under a prescribed state of atmosphere. The algorithm architecture and results from a ten-year global record including global climatology of frequency of occurrence and above-cloud aerosol optical depth, and a discussion on related future field campaigns are presented.

  2. Ten-year fatal and non-fatal myocardial infarction incidence in elderly populations in Spain: the EPICARDIAN cohort study

    PubMed Central

    Gabriel, Rafael; Alonso, Margarita; Reviriego, Blanca; Muñiz, Javier; Vega, Saturio; López, Isidro; Novella, Blanca; Suárez, Carmen; Rodríguez-Salvanés, Francisco

    2009-01-01

    Background In Spain, more than 85% of coronary heart disease deaths occur in adults older than 65 years. However, coronary heart disease incidence and mortality in the Spanish elderly have been poorly described. The aim of this study is to estimate the ten-year incidence and mortality rates of myocardial infarction in a population-based large cohort of Spanish elders. Methods A population-based cohort of 3729 people older than 64 years old, free of previous myocardial infarction, was established in 1995 in three geographical areas of Spain. Any case of fatal and non-fatal myocardial infarction was investigated until December 2004 using the "cold pursuit method", previously used and validated by the the WHO-MONICA project. Results Men showed a significantly (p < 0.001) higher cumulative incidence of myocardial infarction (7.2%; 95%CI: 5.94-8.54) than women (3.8%; 95%CI: 3.06-4.74). Although cumulative incidence increased with age (p < 0.05), gender-differences tended to narrow. Adjusted incidence rates were higher in men (957 per 100 000 person-years) than in women (546 per 100 000 person-years) (p < 0.001) and increased with age (p < 0.001). The increase was progressive in women but not in men. Adjusted mortality rates were also higher in men than in women (p < 0.001), being three times higher in the age group of ≥ 85 years old than in the age group of 65-74 years old (p < 0.001). Conclusion Incidence of fatal and non-fatal myocardial infarction is high in the Spanish elderly population. Men show higher rates than women, but gender differences diminish with age. PMID:19778417

  3. Ten years of progress in the Hokkaido birth cohort study on environment and children's health: cohort profile--updated 2013.

    PubMed

    Kishi, Reiko; Kobayashi, Sachiko; Ikeno, Tamiko; Araki, Atsuko; Miyashita, Chihiro; Itoh, Sachiko; Sasaki, Seiko; Okada, Emiko; Kobayashi, Sumitaka; Kashino, Ikuko; Itoh, Kumiko; Nakajima, Sonomi

    2013-11-01

    The Hokkaido Study on Environment and Children's Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940). The primary goals of this study are to first examine the potential negative effects of perinatal environmental chemical exposures on birth outcomes, including congenital malformations and growth retardation; second, to evaluate the development of allergies, infectious diseases and neurodevelopmental disorders and perform longitudinal observations of the children's physical development to clarify the causal relationship between these outcomes and environmental chemicals; third, to identify individuals genetically susceptible to environmental chemicals; finally, to identify the additive effects of various environmental factors in our daily life, such as secondhand smoke exposure or low folate intake during early pregnancy. In this paper, we introduce our recent progress in the Hokkaido study with a cohort profile updated in 2013. For the last ten years, we followed pregnant women and their offspring, measuring various environmental chemicals, i.e., PCB, OH-PCB and dioxins, PFCs (Perfluorinated Compounds), Organochlorine pesticides, Phthalates, bisphenol A and mercury. We discovered that the concentration of toxic equivalents (TEQ) of dioxin and other specific congeners of PCDF or PCDD have effects on birth weight, infants' neurodevelopment and immune function. There were significant gender differences in these effects; our results suggest that male infants have more susceptibility to those chemical exposures than female infants. Interestingly, we found maternal genetic polymorphisms in AHR, CYP1A1 or GSTs that significantly modified the dioxin concentrations in maternal blood, suggesting different dioxin accumulations in the bodies of individuals with these genotypes, which would lead to different dioxin exposure levels. These genetic

  4. Clinical presentation and treatment outcome of molar pregnancy: Ten years experience at a Tertiary Care Hospital in Dammam, Saudi Arabia

    PubMed Central

    Al-Talib, Ayman A.

    2016-01-01

    Objectives: To study the clinical presentation and treatment outcome of molar pregnancy at a Tertiary Care Hospital in Dammam, Saudi Arabia. Materials and Methods: Reviewed medical records of all molar pregnancy cases among all the deliveries at a tertiary care hospital in Dammam from 2005 to 2014, after approval by institutional ethical review committee. Data abstracted included patient's age, parity, presenting symptoms, gestational age at diagnosis, uterine size, ultrasonographic findings, BhCG level at the time of diagnosis and at follow-up after evacuation, and blood loss during evacuation. Data was entered and analyzed using Excel; frequency distribution for categorical variables and descriptive statistics for continuous variables were computed. Results: Of a total of 25,000 deliveries in ten years, 22 cases of complete molar pregnancy were encountered: 0.9 cases of molar pregnancy per 1000 pregnancies. Majority of patients (63.7%) were older than 35 years, and were nulliparous (45.5%). The commonest symptom was vaginal bleeding (86.4%) followed by hyperemesis gravidarum (41.0%); Hyperthyroidism was seen in 1 patient (4.5%). Ovarian enlargement by theca-lutin cyst was seen in 3 patients (13.6%). The majority of patients (63.6%) had normal BhCG within 9 weeks (63 days) after suction curettage. The majority of the cases followed a benign course. Conclusion: Aged older than 35 years seems a risk factor and vaginal bleeding is the commonest presenting symptom. Early booking of pregnant women to antenatal care clinics and routine first trimester ultrasound made diagnosis easier and earlier before complications appear. PMID:27625583

  5. Increasing Trends of Diabetes Mellitus and Body Weight: A Ten Year Observation at Gondar University Teaching Referral Hospital, Northwest Ethiopia

    PubMed Central

    Abebe, Solomon Mekonnen; Berhane, Yemane; Worku, Alemayehu; Alemu, Shitay

    2013-01-01

    Background Diabetes mellitus is becoming one of the major causes of premature adult mortality in developing countries. However, there is a very little documentation of the morbidity trend in such countries. Objective To assess the ten-year trend of diabetes mellitus at Gondar University Teaching Referral Hospital, northwest Ethiopia. Methods A hospital-based retrospective record review was done at the main referral hospital in northwest Ethiopia. Data were obtained from medical records of all registered diabetic patients in the Diabetic Follow up Clinic between 2000 and 2009. An Extended Mantel-Haenzel chi-square test for the linear trend was used to examine the trend over time. Result Out of the total 354,524 patients who visited the Outpatient Department of the hospital during the study period, 1553 (4.4/1000) were diabetes patients, of which 50.1% was type 1 and 49.9% type 2 diabetes mellitus. The average increase in the proportion of both Type 1 and Type 2 diabetes mellitus cases between 2000 and 2009 was 125%. The mean (±SD) age for Type 1 diabetes mellitus was 29.1 (±12), and 53.5 (±12) for Type 2 diabetes. Overall 42.5% of the diabetes mellitus patients were female and 31.7% were rural residents. The mean body mass index for both type of diabetes mellitus increased from 15.9 to 18.3 kg for type 1 and from 23.8 to 24.6 for type 2 between 2000 and 2009, respectively. Conclusion The number of diabetes mellitus cases seen at Gondar Referral Hospital is rising steadily. A comprehensive diabetes prevention, treatment, and care program is needed to improve the quality of life of the increasing diabetes mellitus cases in Ethiopia. PMID:23536904

  6. The Effect of Donor Diabetes History on Graft Failure and Endothelial Cell Density Ten Years after Penetrating Keratoplasty

    PubMed Central

    Lass, Jonathan H.; Riddlesworth, Tonya D.; Gal, Robin L.; Kollman, Craig; Benetz, Beth A.; Price, Francis W.; Sugar, Alan; Terry, Mark A.; Soper, Mark; Beck, Roy W.

    2014-01-01

    Objective To examine the long term effect of donor diabetes history on graft failure and endothelial cell density (ECD) after penetrating keratoplasty (PKP) in the Cornea Donor Study Design Multi-center prospective, double-masked, controlled clinical trial Participants 1090 subjects undergoing PKP for a moderate risk condition, principally Fuchs’ dystrophy or pseudophakic/aphakic corneal edema (PACE), were enrolled by 105 surgeons from 80 clinical sites in the United States. Methods Corneas from donors 12 to 75 years old were assigned by 43 eye banks to participants without respect to recipient factors. Donor and recipient diabetes status was determined from existing medical records. Images of the central endothelium were obtained preoperatively (baseline) and at intervals for ten years postoperatively and analyzed by a central image analysis reading center to determine ECD. Main Outcome Measure(s) Time to graft failure (regraft or cloudy cornea for 3 consecutive months) and ECD. Results There was no statistically significant association of donor diabetes history with 10-year graft failure, baseline ECD, 10-year ECD or ECD values longitudinally over time in unadjusted analyses nor after adjusting for donor age and other significant covariates. The 10-year graft failure rate was 23% in the 199 cases receiving a cornea from a donor with diabetes versus 26% in the 891 cases receiving a cornea from a donor without diabetes (95% confidence interval for the difference: −10% to +6%; unadjusted p = 0.60). Baseline ECD (p=0.71), 10-year ECD (p>0.99), and changes in ECD over 10 years (p=0.86) were similar comparing donor diabetes and no-diabetes groups. Conclusions and Relevance The study results do not suggest an association between donor diabetes and PKP outcome. However, the assessment of donor diabetes was imprecise and based on historical data only. The increasing frequency of diabetes in the aging population in the United States affects the donor pool, thus the

  7. Atmospheric wet deposition of nitrogen and sulfur to a typical red soil agroecosystem in Southeast China during the ten-year monsoon seasons (2003-2012)

    NASA Astrophysics Data System (ADS)

    Cui, Jian; Zhou, Jing; Peng, Ying; He, Yuanqiu; Yang, Hao; Mao, Jingdong

    2014-01-01

    Biological processes in agroecosystems have been affected by atmospheric nitrogen (N) and sulfur (S) deposition, but there is uncertainty about their deposition characteristics in the monsoon season. We collected rain samples using an ASP-2 sampler, recorded rainfall and rain frequency by an auto-meteorological experiment sub-station, and determined total N, NO3--N and NH4+-N levels in precipitation with an AutoAnalyzer 3 and SO42--S with a chromatography, in order to characterize the wet deposition of N and S to a typical red soil agroecosystem by a ten-year monitoring experiment in Southeast China. The results indicated that N and S wet deposition had an increased trend with the flux of total N (3.34-65.17 kg ha-1 N) and total S (SO42--S) (7.17-23.44 kg ha-1 S) during the monsoon seasons. The additional applications of pig mature in 2006 and 2007 led to the peaks of DON (dissolved organic nitrogen) and total N wet deposition. On average, NH4+-N was the major N form, accounting for 48.5% of total N wet deposition and DON was not a negligible N form, accounting for 20.8% during the ten-year monsoon seasons (except 2006 and 2007). Wet deposition of N and S has been intensively influenced by human activities in the monsoon season, and would increase the potential ecological risk in the red soil agricultural ecosystem.

  8. Spatial distribution and temporal variation of aerosol optical depth in the Sichuan basin, China, the recent ten years

    NASA Astrophysics Data System (ADS)

    Liu, Xinyu; Chen, Quanliang; Che, Huizheng; Zhang, Renjian; Gui, Ke; Zhang, Huan; Zhao, Tianliang

    2016-12-01

    The applicability of the MODIS (Moderate Resolution Imaging Spectroradiometer) aerosol optical depth (AOD) product was verified using CE-318 sun photometric data for the Sichuan area. The results show that MODIS_3K AOD agrees well with the AOD derived from the CE-318 sun photometer, with a high correlation coefficient (R2 = 0.91). And we used the MODIS AOD product analyzed the spatial distribution and temporal variation of the annual, seasonal and monthly distribution of AOD in the Sichuan area over the last ten years (2006-2015). In the Sichuan area, the mean change of AOD over the 10-year period showed a significant decreasing trend, reaching its maximum in 2010 and its minimum in 2015. Considering only the first five years, the lowest value was reached in 2008 and the overall trend was a standard symmetrical "V" type. Over the later five years, the annual average AOD value showed an overall decreasing trend. The monthly averaged AOD indicated a "double peaks" fluctuation trend; the two peaks appeared in March and August, and AOD changes were relatively small between September and January. Overall, the average value of AOD reached its highest values in spring, and its lowest values in autumn. In the city of Chengdu, the monthly and seasonal changes in the trend were essentially the same as those of the whole Sichuan area; However, the Chengdu AOD monthly and seasonal average change rate was higher than that of Sichuan as a whole. This shows that Chengdu is still the main contributor to the enhanced AOD value for the entire Sichuan region. The spatial distribution of AOD values indicates an "east high, west low" situation across the Sichuan area and Chengdu is one of three cities with the highest AOD values. However, the spatial variation of AOD trend value indicated an "east low, west high" the spatial distribution across the Sichuan region, opposite to the spatial distribution. Moreover, in the past 10 years, the overall AOD changes in Sichuan showed a downward

  9. Preoperative evaluation and outcome of corneal transplantation for limbal dermoids: a ten-year follow-up study

    PubMed Central

    Xin, Meng; Gong, Yue-Rong; Jiang, Shan-Hao; Dai, Chun-Hua; Li, Su-Xia; Shi, Wei-Yun

    2016-01-01

    AIM To summarize preoperative evaluation and outcome of corneal transplantation for limbal dermoids for ten years. METHODS Eighty-five patients diagnosed with limbal dermoids and treated with corneal transplantation were analyzed retrospectively. All patients were further divided into two groups according to absence or presence of neovascularization surrounding the dermoids in the corneal stroma. Eighty-two eyes were treated with tumor excision combined with partial lamellar sclerokeratoplasty, and the other three eyes were performed by penetrating keratoplasty. The size and location of the tumor, the associated ocular and systemic anomalies, the depth of the corneal penetration of tumor tissues, the preoperative and postoperative best-corrected visual acuity (BCVA), graft survival and cosmetic outcome, and surgical complications were recorded respectively. RESULTS The average age at surgery was 5.3y (range, 3mo-36y). The mean size of dermoids was 6.1±1.6 mm. The 43.5% of eyes (37/85) were present with hair at the surface of the dermoid and 72.9% of dermoids were located inferotemporal of the eye. Amplyopia was present in 34.1% of patients (29/85) and 9.4% of patients (8/85) had lipodermoids. Eighteen patients suffered from Goldenhar's syndrome with an accessory ear. The 75% of patients in group 1 had involvement of the corneal deep stroma down to Descemet's membrane without involving it, but 71.4% of patients had Descemet's membrane involvement in group 2. Preoperative BCVA ranged from counting fingers to 20/20. Postoperatively 81.1% had a BCVA of 20/800 or better. There was no significant difference between the post-surgical BCVA of the two groups (t=1.584, P>0.05). The grafts of 70.5% patients were present as 1+ opacity, 21.1% as 2+ opacity, 8.2% as 3+ opacity and none as 4+ opacity. Surgical complications included graft rejection, microperforation, prolonged reepithelialization, steroid glaucoma, interface neovascularization, and interface hemorrhage

  10. Preparing Science-Trained Professionals for the Biotechnology Industry: A Ten-Year Perspective on a Professional Science Master's Program.

    PubMed

    Hamilton, Paul T; Luginbuhl, Sarah C; Hyman, Michael

    2012-01-01

    The biotechnology industry has a need for business-savvy scientists; however, this is not the way scientists are traditionally trained at universities and colleges. To address this need, universities have developed Professional Science Master's (PSM) degree programs that offer advanced training in a technical field along with professional skills development through team-based projects and internships. Nearly ten years ago, the Department of Microbiology at NCSU started a PSM program in Microbial Biotechnology (MMB). This article provides an overview of the MMB program, and shares some of the lessons that we have learned.

  11. Duration of Sexual Harassment and Generalized Harassment in the Workplace Over Ten Years: Effects on Deleterious Drinking Outcomes

    PubMed Central

    McGinley, Meredith; Richman, Judith A.; Rospenda, Kathleen M.

    2012-01-01

    While harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a ten year longitudinal mail survey, university employees (N = 2265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gender, age, and race) predicted the shape of the trajectories and likelihood of class membership. As hypothesized, membership in the chronic harassment classes was linked to future problematic drinking, even after controlling for previous drinking. PMID:21745045

  12. Position Paper on Use of Stereoscopy to Support Science Learning: Ten Years of Research

    ERIC Educational Resources Information Center

    Price, C. Aaron; Lee, Hee-Sun; Plummer, Julia D.; SubbaRao, Mark; Wyatt, Ryan

    2015-01-01

    Stereoscopy's potential as a tool for science education has been largely eclipsed by its popularity as an entertainment platform and marketing gimmick. Dozens of empirical papers have been published in the last decade about the impact of stereoscopy on learning. As a result, a corpus of research now points to a coherent message about how, when,…

  13. Near-infrared laser treatment of complicated hemangiomas in children: ten-year clinical experience

    NASA Astrophysics Data System (ADS)

    Abushkin, Ivan A.; Privalov, Valeriy A.; Lappa, Alexander V.

    2011-03-01

    Results of application of low invasive laser technology (developed by authors: Proc. SPIE 5863, 107-115 (2005), Russian Federation patent No.2290228 of.27.12.06) to treatment of hemangiomas in children are presented and analyzed in this work. From 2001 the technology was applied to about 1500 children with more than 2000 hemangiomas. Majority of them were complicated ones: belong to cavernous or combined types or (and) were localized on problem places: on face near eyes, nose, and lips, on auricles, on perineum near anus and genitals, in respiratory and gastrointestinal tracts. Diode laser with wavelength 920, 970, and 1060 nm at distant and interstitial irradiation were applied. In case of need there applied endoscopes. Excellent and good results have been achieved in 94% cases; there was a significant improvement in the rest cases.

  14. Ten Years of Vegetation Change in Northern California Marshlands Detected using Landsat Satellite Image Analysis

    NASA Technical Reports Server (NTRS)

    Potter, Christopher

    2013-01-01

    The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology was applied to detected changes in perennial vegetation cover at marshland sites in Northern California reported to have undergone restoration between 1999 and 2009. Results showed extensive contiguous areas of restored marshland plant cover at 10 of the 14 sites selected. Gains in either woody shrub cover and/or from recovery of herbaceous cover that remains productive and evergreen on a year-round basis could be mapped out from the image results. However, LEDAPS may not be highly sensitive changes in wetlands that have been restored mainly with seasonal herbaceous cover (e.g., vernal pools), due to the ephemeral nature of the plant greenness signal. Based on this evaluation, the LEDAPS methodology would be capable of fulfilling a pressing need for consistent, continual, low-cost monitoring of changes in marshland ecosystems of the Pacific Flyway.

  15. Ten Years of Forest Cover Change in the Sierra Nevada Detected Using Landsat Satellite Image Analysis

    NASA Technical Reports Server (NTRS)

    Potter, Christopher S.

    2014-01-01

    A detailed geographic record of recent vegetation regrowth and disturbance patterns in forests of the Sierra Nevada remains a gap that can be filled with remote sensing data. Landsat (TM) imagery was analyzed to detect 10 years of recent changes (between 2000 and 2009) in forest vegetation cover for areas burned by wildfires between years of 1995 to 1999 in the region. Results confirmed the prevalence of regrowing forest vegetation during the period 2000 and 2009 over 17% of the combined burned areas.

  16. Ten-Year Aging of Elastomeric Vulcanizates in Panama, Alaska, and Illinois

    DTIC Science & Technology

    1974-07-01

    Rycar h021 { Zk ^JF), and Genthane SR (Z60DU) vulcanizates where tensile strength deterioration is the best cri- terion of the change which takes...reversion over a period of many months., The cracking appears to result from microbiological attack. The hydrolytic decomposition of polyester urethanes...Commander U. S. Army Medical Biomechanical Research Laboratory ATTN: Library Fort Detrick, Bldg. 56ö Frederick, MD 21701 Commander Natick

  17. 9/11 Ten Years After: Command, Control, Communications Remain an Issue

    DTIC Science & Technology

    2012-02-09

    terrorist bombing of the World Trade Center ( WTC ) revealed significant C3 issues. Responding forces were dispatched by different control centers and were...communication was lost with responding forces inside the WTC ; radios could not penetrate the numerous steel and concrete floors; and too many units using the...responding to the incident and from effectively performing their primary mission to protect the public. As a result of the 1993 WTC bombing, NY/NJ Port

  18. Ten years of preanalytical monitoring and control: Synthetic Balanced Score Card Indicator

    PubMed Central

    López-Garrigós, Maite; Flores, Emilio; Santo-Quiles, Ana; Gutierrez, Mercedes; Lugo, Javier; Lillo, Rosa; Leiva-Salinas, Carlos

    2015-01-01

    Introduction Preanalytical control and monitoring continue to be an important issue for clinical laboratory professionals. The aim of the study was to evaluate a monitoring system of preanalytical errors regarding not suitable samples for analysis, based on different indicators; to compare such indicators in different phlebotomy centres; and finally to evaluate a single synthetic preanalytical indicator that may be included in the balanced scorecard management system (BSC). Materials and methods We collected individual and global preanalytical errors in haematology, coagulation, chemistry, and urine samples analysis. We also analyzed a synthetic indicator that represents the sum of all types of preanalytical errors, expressed in a sigma level. We studied the evolution of those indicators over time and compared indicator results by way of the comparison of proportions and Chi-square. Results There was a decrease in the number of errors along the years (P < 0.001). This pattern was confirmed in primary care patients, inpatients and outpatients. In blood samples, fewer errors occurred in outpatients, followed by inpatients. Conclusion We present a practical and effective methodology to monitor unsuitable sample preanalytical errors. The synthetic indicator results summarize overall preanalytical sample errors, and can be used as part of BSC management system. PMID:25672466

  19. Ten Years of Linear Endobronchial Ultrasound: Evidence of Efficacy, Safety and Cost-effectiveness.

    PubMed

    Fernández-Villar, Alberto; Mouronte-Roibás, Cecilia; Botana-Rial, Maribel; Ruano-Raviña, Alberto

    2016-02-01

    Real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is one of the major landmarks in the history of bronchoscopy. In the 10 years since it was introduced, a vast body of literature on the procedure and its results support the use of this technique in the study of various mediastinal and pulmonary lesions. This article is a comprehensive, systematic review of all the available scientific evidence on the more general indications for this technique. Results of specific studies on efficacy, safety and cost-effectiveness available to date are examined. The analysis shows that EBUS-TBNA is a safe, cost-effective technique with a high grade of evidence that is a valuable tool in the diagnosis and mediastinal staging of patients with suspected or confirmed lung cancer. However, more studies are needed to guide decision-making in the case of a negative result. Evidence on the role of EBUS-TBNA in the diagnosis of sarcoidosis and extrathoracic malignancies is also high, but much lower when used in the study of tuberculosis, lymphoma and for the re-staging of lung cancer after neoadjuvant chemotherapy. Nevertheless, due to its good safety record and lack of invasiveness compared to surgical techniques, the grade of evidence for recommending EBUS-TBNA as the initial diagnostic test in patients with these diseases is very high in most cases.

  20. Granulomatous Mastitis: A Ten-Year Experience at a University Hospital

    PubMed Central

    Korkut, Ercan; Akcay, Mufide Nuran; Karadeniz, Erdem; Subasi, Irmak Durur; Gursan, Nesrin

    2015-01-01

    Objective: In this study we aimed to define clinical, radiologic and pathological specialties of patients who applied to General Surgery Department of Atatürk University Medical Faculty with granulomatous mastitis and show medical and surgical treatment results. With the help of this study we will be able to make our own clinical algorithm for diagnosis and treatment. Materials and Methods: We searched retrospectively addresses, phone numbers and clinical files of 93 patients whom diagnosed granulomatous mastitis between a decade of January 2001 – December 2010. We noted demographic specialties, ages, gender, medical family history, main complaints, physical findings, radiological and laboratory findings, medical treatments, postoperative complications and surgical procedures if they were operated; morbidity, recurrence and success ratios, complications after treatment for patients discussed above. Results: In this study we evaluated 93 patients, 91 females and 2 males, with granulomatous mastitis retrospectively who applied to General Surgery Department of Atatürk University Medical Faculty between January 2001 and December 2010. Mean age was 34.4 years. The diagnosis was confirmed by histopathologic examination of the lesions. Seventy three patients had idiopathic granulomatous lobular mastitis and 20 patients had specific granulomatous mastitis IGM (18 tuberculosis mastitis, 1 alveolar echinococcosis and 1 silk reaction). All the patients had surgical debridement or antibiotic, and anti-inflammatory treatment with results bad clinical response before applied our clinic. Conclusion: Empiric antibiotic therapy and drainage of the breast lesions are not enough for complete remission of idiopathic granulomatous mastitis. The lesion must be excised completely. In selected patients, corticosteroid therapy can be useful. In the patients with tuberculous mastitis, abscess drainage and antituberculous therapy can be useful, but wide excision must be chosen for the

  1. Respiratory function measurements in a cohort of medical students: a ten-year follow-up.

    PubMed Central

    Lawther, P J; Brooks, A G; Waller, R E

    1978-01-01

    A cohort of medical students first seen in 1962 has now been examined for a third time. The prevalence of symptoms of cough, phlegm, and breathlessness among them has remained low, and smoking habits have been light in comparison with those of the general population. Results of the three successive sets of measurements of lung function indicate that, in general, optimum values were reached in the early 20s, with little further change up to age 29. There was some evidence of reduced ventilatory capacity in subjects with histories of acute chest illnesses. PMID:746504

  2. Using a natural abilities battery for academic and career guidance: a ten-year study.

    PubMed

    Brown, Corrie C; Harvey, Stephen B; Stiles, Dori

    2011-01-01

    Over a period of 10 years, first-year students from 11 consecutive veterinary classes conducted a self-assessment using a natural abilities survey. The present study analyzes the data compiled from students' self-assessment results. As a group, veterinary students are exceptional problem solvers, either through inductive or deductive reasoning, and have strong spatial relations capacities. Veterinary students have a range of learning styles with design memory being the primary vehicle for information delivery and tonal memory being the least frequently used style overall. Information gained on each student's natural abilities can be used to guide effective career decision making and enhance prospects for long-term career satisfaction.

  3. Parental perceptions of children's modesty: a cross-sectional survey of ages two to ten years.

    PubMed

    Rosenfeld, A; Siegel-Gorelick, B; Haavik, D; Duryea, M; Wenegrat, A; Martin, J; Bailey, R

    1984-11-01

    Modesty has been defined as decorum in relation to physical nakedness, and sexual and eliminative behavior (Newson and Newson 1968). The connection between nakedness, sexuality, and modesty with respect to family members dates back millennia. Leviticus prohibited incest with the phrase, "Thou shalt not uncover the nakedness of ..." and then specified a lengthy list of forbidden relatives. We will review contemporary theories and research projects concerning modesty and then discuss the results of a study we designed in order to investigate age trends in the development of modesty.

  4. Ten-Year Retrospective Longitudinal-Study of Student Perspectives on Value of REU

    NASA Astrophysics Data System (ADS)

    Slater, T. F.; Slater, S. J.

    2013-12-01

    For more than two decades, federal agencies have been enthusiastically supporting summer research experiences for undergraduates. These REU programs are tacitly intended to increase retention and provide "an important educational experience" for undergraduates, particularly women, minorities and underrepresented groups. Numerous authors (viz., Laursen, Lopatto, Dolan, among many others) have enthusiastically described positive impacts of summer REU programs from exit interview data. These results include enhanced persistence to pursue STEM careers and confirmed desire to attend graduate school in the field targeted by a particular REU. Perhaps surprisingly, negative student experiences are rarely described in the scholarly literature, but do appear in more informal publications (viz., Gueterma, 2007). One wonders how REU alumni, looking back over their entire collective portfolio of experiences, now perceive the educational value of their REU experience relative to their other educational experiences. To obtain a backwards-looking, reflective description from REU alumni on the value of their REU experiences, we conducted a 10-year, two-stage study was designed to explore the ways in which the REU acted as an educational experience for 51 women from a single geoscience sub-discipline. The first phase was an ex post facto longitudinal analysis of data, including multiple interviews with each participant during their REU, annual open-ended alumni surveys, faculty interviews, and extensive field notes, over a 10-year period. This analysis informed the second phase, a clinical interview. Over 10 hours of interviews with 8 participants were conducted and analyzed. These 8 participants were selected to represent a variety of career stages, and for their potential to reflect on a wide variety of educational experiences. Results from the interviews, done many years after their REU experience, indicate that the interviewees' REU did not provide a substantive educational

  5. Relaxation training for anxiety: a ten-years systematic review with meta-analysis

    PubMed Central

    Manzoni, Gian Mauro; Pagnini, Francesco; Castelnuovo, Gianluca; Molinari, Enrico

    2008-01-01

    Background Relaxation training is a common treatment for anxiety problems. Lacking is a recent quantitative meta-analysis that enhances understanding of the variability and clinical significance of anxiety reduction outcomes after relaxation treatment. Methods All studies (1997–2007), both RCT, observational and without control group, evaluating the efficacy of relaxation training (Jacobson's progressive relaxation, autogenic training, applied relaxation and meditation) for anxiety problems and disorders were identified by comprehensive electronic searches with Pubmed, Psychinfo and Cochrane Registers, by checking references of relevant studies and of other reviews. Our primary outcome was anxiety measured with psychometric questionnaires. Meta-analysis was undertaken synthesizing the data from all trials, distinguishing within and between effect sizes. Results 27 studies qualified for the inclusion in the meta-analysis. As hypothesized, relaxation training showed a medium-large effect size in the treatment of anxiety. Cohen's d was .57 (95% CI: .52 to .68) in the within analysis and .51 (95% CI: .46 to .634) in the between group analysis. Efficacy was higher for meditation, among volunteers and for longer treatments. Implications and limitations are discussed. Conclusion The results show consistent and significant efficacy of relaxation training in reducing anxiety. This meta-analysis extends the existing literature through facilitation of a better understanding of the variability and clinical significance of anxiety improvement subsequent to relaxation training. PMID:18518981

  6. High satisfaction rate ten years after bilateral prophylactic mastectomy - a longitudinal study.

    PubMed

    Wasteson, E; Sandelin, K; Brandberg, Y; Wickman, M; Arver, B

    2011-07-01

    Women from families with an increased risk for breast/ovarian cancer have undergone bilateral prophylactic mastectomy (BPM) since the early 1990s at the Karolinska University Hospital in Sweden. Perceptions of BPM as reported by the first women who underwent the procedure have previously been evaluated on a short-term basis (1-3 years). The present study aims to evaluate the long-term (10 years) physical and psychological consequences of BPM in the same cohort of women. Some of the very first women to undergo BPM participated in the present interview study (n= 13). The semi-structured interviews focused on the women's long-term experiences related to BPM and immediate breast reconstruction. Overall, the women were satisfied with their decision to undergo BPM and perceived a negligible remaining risk of getting breast cancer. For most women, the operation had not resulted in changes in family life or lifestyle (n= 8), although some described that the relationship with their spouse was affected (8/13), either in a negative (n= 5) or positive (n= 3) way. The cosmetic results were mainly positive (n= 10). Recurrent counselling and support during the whole process of decision, treatment and follow up is recommended.

  7. Ten Years of Patient Surveys in Accredited Breast Centers in North Rhine-Westphalia

    PubMed Central

    Ansmann, L.; Kowalski, C.; Pfaff, H.

    2016-01-01

    Introduction: Patient surveys are an established tool for quality control in healthcare organizations. This report looks at the design and development of the annual patient surveys carried out among breast cancer patients treated in the Breast Centers of North Rhine-Westphalia and discusses selected findings from 10 consecutive years. Material and Methods: Since 2006 the Institute for Medical Sociology, Health Services Research and Rehabilitation Science (IMVR) of the University of Cologne has carried out an annual survey of breast cancer patients using the Cologne Patient Questionnaire for Breast Cancer. The patients included in the survey have been diagnosed with primary breast cancer and undergo surgery between February and July in one of the Breast Centers in North Rhine-Westphalia accredited by the medical association of Westphalia-Lippe. The questionnaire and the type of feedback given to the Breast Centers were comprehensively revised in 2014. Selected results collected over the survey period were analyzed descriptively. Results: The survey period of 10 years provides information on the actual medical care delivered in the Breast Centers based on the data obtained in this period from around 40 000 patients. Some areas showed positive developments over time. Conclusion: The approach used to survey patients, the Cologne Patient Questionnaire for Breast Cancer 2.0 and the benchmark-focused feedback provide an impetus for organizational learning in Breast Centers. The concept could also be used in other healthcare organizations to stimulate learning and improve healthcare services. PMID:26855439

  8. Ten Years of Forest Cover Change in the Sierra Nevada Detected Using Landsat Satellite Image Analysis

    NASA Technical Reports Server (NTRS)

    Potter, Christopher S.

    2014-01-01

    The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology was applied to detected changes in forest vegetation cover for areas burned by wildfires in the Sierra Nevada Mountains of California between the periods of 1975- 79 and 1995-1999. Results for areas burned by wildfire between 1995 and 1999 confirmed the importance of regrowing forest vegetation over 17% of the combined burned areas. A notable fraction (12%) of the entire 5-km (unburned) buffer area outside the 1995-199 fires perimeters showed decline in forest cover, and not nearly as many regrowing forest areas, covering only 3% of all the 1995-1999 buffer areas combined. Areas burned by wildfire between 1975 and 1979 confirmed the importance of disturbed (or declining evergreen) vegetation covering 13% of the combined 1975- 1979 burned areas. Based on comparison of these results to ground-based survey data, the LEDAPS methodology should be capable of fulfilling much of the need for consistent, low-cost monitoring of changes due to climate and biological factors in western forest regrowth following stand-replacing disturbances.

  9. Precipitation Climatology over Mediterranean Basin from Ten Years of TRMM Measurements

    NASA Technical Reports Server (NTRS)

    Mehta, Amita V.; Yang, Song

    2008-01-01

    Climatological features of mesoscale rain activities over the Mediterranean region between 5 W-40 E and 28 N-48 N are examined using the Tropical Rainfall Measuring Mission (TRMM) 3B42 and 2A25 rain products. The 3B42 rainrates at 3-hourly, 0.25 deg x 0.25 deg spatial resolution for the last 10 years (January 1998 to July 2007) are used to form and analyze the 5-day mean and monthly mean climatology of rainfall. Results show considerable regional and seasonal differences of rainfall over the Mediterranean Region. The maximum rainfall (3-5 mm/day) occurs over the mountain regions of Europe, while the minimum rainfall is observed over North Africa (approximately 0.5 mm/day). The main rainy season over the Mediterranean Sea extends from October to March, with maximum rainfall occurring during November-December. Over the Mediterranean Sea, an average rainrate of approximately 1-2 mm/day is observed, but during the rainy season there is 20% larger rainfall over the western Mediterranean Sea than that over the eastern Mediterranean Sea. During the rainy season, mesoscale rain systems generally propagate from west to east and from north to south over the Mediterranean region, likely to be associated with Mediterranean cyclonic disturbances resulting from interactions among large-scale circulation, orography, and land-sea temperature contrast.

  10. Dosimetric Consistency of Co-60 Teletherapy Unit- a ten years Study

    PubMed Central

    Baba, Misba H; Mohib-ul-Haq, M.; Khan, Aijaz A.

    2013-01-01

    Objective The goal of the Radiation standards and Dosimetry is to ensure that the output of the Teletherapy Unit is within ±2% of the stated one and the output of the treatment dose calculation methods are within ±5%. In the present paper, we studied the dosimetry of Cobalt-60 (Co-60) Teletherapy unit at Sher-I-Kashmir Institute of Medical Sciences (SKIMS) for last 10 years. Radioactivity is the phenomenon of disintegration of unstable nuclides called radionuclides. Among these radionuclides, Cobalt-60, incorporated in Telecobalt Unit, is commonly used in therapeutic treatment of cancer. Cobalt-60 being unstable decays continuously into Ni-60 with half life of 5.27 years thereby resulting in the decrease in its activity, hence dose rate (output). It is, therefore, mandatory to measure the dose rate of the Cobalt-60 source regularly so that the patient receives the same dose every time as prescribed by the radiation oncologist. The under dosage may lead to unsatisfactory treatment of cancer and over dosage may cause radiation hazards. Our study emphasizes the consistency between actual output and output obtained using decay method. Methodology The methodology involved in the present study is the calculations of actual dose rate of Co-60 Teletherapy Unit by two techniques i.e. Source to Surface Distance (SSD) and Source to Axis Distance (SAD), used for the External Beam Radiotherapy, of various cancers, using the standard methods. Thereby, a year wise comparison has been made between average actual dosimetric output (dose rate) and the average expected output values (obtained by using decay method for Co-60.) Results The present study shows that there is a consistency in the average output (dose rate) obtained by the actual dosimetry values and the expected output values obtained using decay method. The values obtained by actual dosimetry are within ±2% of the expected values. Conclusion The results thus obtained in a year wise comparison of average output by

  11. Ten-Year Follow-Up of Endovascular Aneurysm Treatment with Talent Stent-Grafts

    SciTech Connect

    Pitton, Michael B. Scheschkowski, Tobias; Ring, Markus; Herber, Sascha; Oberholzer, Katja; Leicher-Dueber, Annegret; Neufang, Achim; Schmiedt, Walther; Dueber, Christoph

    2009-09-15

    The purpose of this study was to evaluate the clinical results, complications, and secondary interventions during long-term follow-up after endovascular aneurysm repair (EVAR) and to investigate the impact of endoleak sizes on aneurysm shrinkage. From 1997 to March 2007, 127 patients (12 female, 115 male; age, 73.0 {+-} 7.2 years) with abdominal aortic aneurysms were treated with Talent stent-grafts. Follow-up included clinical visits, contrast-enhanced MDCT, and radiographs at 3, 6, and 12 months and then annually. Results were analyzed with respect to clinical outcome, secondary interventions, endoleak rate and management, and change in aneurysm size. There was no need for primary conversion surgery. Thirty-day mortality was 1.6% (two myocardial infarctions). Procedure-related morbidity was 2.4% (paraplegia, partial infarction of one kidney, and inguinal bleeding requiring surgery). Mean follow-up was 47.7 {+-} 34.2 months (range, 0-123 months). Thirty-nine patients died during follow-up; three of the deaths were related to aneurysm (aneurysm rupture due to endoleak, n = 1; secondary surgical reintervention n = 2). During follow-up, a total of 29 secondary procedures were performed in 19 patients, including 14 percutaneous procedures (10 patients) and 15 surgical procedures (12 patients), including 4 cases with late conversion to open aortic repair (stent-graft infection, n = 1; migration, endoleak, or endotension, n = 3). Overall mean survival was 84.5 {+-} 4.7 months. Mean survival and freedom from any event was 66.7 {+-} 4.5 months. MRI depicted significantly more endoleaks compared to MDCT (23.5% vs. 14.3%; P < 0.01). Patients in whom all aneurysm side branches were occluded prior to stent-grafting showed a significantly reduced incidence of large endoleaks. Endoleaks >10% of the aneurysm area were associated with reduced aneurysm shrinkage compared to no endoleaks or <10% endoleaks ({Delta} at 3 years, -1.8% vs. -12.0%; P < 0.05). In conclusion, endovascular

  12. [A bibliometrics study of literature on medical image processing for the past ten years].

    PubMed

    Chen, Wei; Wang, Yanbin; Ouyang, Zhaolian; Guo, Wenjiao; Chi, Hui

    2014-02-01

    We searched and retrieved literature on the topic of medical image processing published on SCI journals in the past 10 years. We then imported the retrieved literature into TDA for data cleanup before data analysis and pro cessing by EXCLE and UCINET to generate tables and figures that could indicate disciplinary correlation and research hotspots from the perspective of bibliometrics. The results indicated that people in Europe and USA were leading researchers on medical image processing with close international cooperation. Many disciplines contributed to the fast development of medical image processing with intense interdisciplinary researches. The papers that we found show recent research hotspots of the algorithm, system, model, image and segmentation in the field of medical image processing. Cluster analysis on key words of high frequency demonstrated complicated clustering relationship.

  13. Photodynamic therapy on spontaneous tumors of dogs and cats: a ten-year study

    NASA Astrophysics Data System (ADS)

    Fonda, Diego

    1992-06-01

    Since 1981, more than fifty spontaneous tumors of dogs and cats were treated by photodynamic therapy with hematoporphyrins in the surgery department of the University of Milan. Therapeutic results proved to be successful and promising in certain forms of cancer and will be compared in the future with the effectiveness of other photosensitizer drugs like phatolocyanines derivatives. Applied hematoporphyrins phototherapy methods included: (1) injection of hematoporphyrins derivative (HpD) and irradiation with laser light at 631 nanometers, using a Rhodamine B dye laser; (2) injection of the active component of hematoporphyrin derivative (DHE) and irradiation with a Rhodamine B dye laser; and (3) injection of DHE and irradiation with laser light at 628 nanometers using a gold vapor laser. More frequently treated tumor sites were oral and nasal cavities. Other localizations were mucous membranes of the glans and stomach. Nineteen histological types were diagnosed in treated tumors.

  14. Consequences of the Chernobyl fallout on some Italian underbrush produces: A ten-year study

    SciTech Connect

    Malanca, A.; Pessina, V.; Dallara, G.

    1996-11-01

    In this paper we present the results of a decennial (1986-1995) investigation on radiocaesium concentrations in soil, honey, mushrooms and other underbrush produces collected in a representative upland region of the Italian Apennines. Concentrations of {sup 134}Cs and {sup 137}Cs in numerous samples were determined by gamma-ray spectrometry. The data obtained showed a relatively high {sup 137}Cs concentration, up to 8973 Bq m{sup -2}, in the superficial (0-2 cm) mineral soil. In most of the mushrooms, as well as in other underbrush produces, the detected activities were generally <20 Bq kg{sup -1}. However, a high radiocontamination was observed in two species, namely Rozites Caperatus (with 584 and 735 Bq kg{sup -1} of {sup 137}Cs), and Tricholoma Nudum (3450 Bq kg{sup -1} ). Caesium concentration in honey showed a sharp increase soon after the Chernobyl accident, followed by a slow progressive decrease. 11 refs., 3 tabs.

  15. Ten years of mercury measurement at urban and industrial air quality monitoring stations in the UK

    NASA Astrophysics Data System (ADS)

    Brown, Richard J. C.; Goddard, Sharon L.; Butterfield, David M.; Brown, Andrew S.; Robins, Chris; Mustoe, Chantal L.; McGhee, Elizabeth A.

    2015-05-01

    Concentrations and trends from a decade of measurements of total gaseous mercury and particulate phase mercury at a number of monitoring stations across the UK are presented. Both emissions and ambient concentrations of mercury in the UK have continued to fall slightly during the measurement period despite already being at historically low levels. The median UK concentration of total gaseous mercury recorded in recent years was around 2.0 ng/m3. Small urban increments of about 0.4 ng/m3 above background concentrations were noted, with larger increments above the background only observed close to industrial point sources. The total gaseous mercury to particulate phase mercury ratio was large across the UK - indicating the dominance of the gaseous mercury in the atmosphere - and was observed to be larger at background and urban locations than at industrial sites, as a result of higher relative particulate phase mercury concentrations close to primary emissions point sources.

  16. Ten-year outcome of enzyme replacement therapy with agalsidase beta in patients with Fabry disease

    PubMed Central

    Germain, Dominique P; Charrow, Joel; Desnick, Robert J; Guffon, Nathalie; Kempf, Judy; Lachmann, Robin H; Lemay, Roberta; Linthorst, Gabor E; Packman, Seymour; Scott, C Ronald; Waldek, Stephen; Warnock, David G; Weinreb, Neal J; Wilcox, William R

    2015-01-01

    Background Fabry disease results from deficient α-galactosidase A activity and globotriaosylceramide accumulation causing renal insufficiency, strokes, hypertrophic cardiomyopathy and early demise. We assessed the 10-year outcome of recombinant α-galactosidase A therapy. Methods The outcomes (severe clinical events, renal function, cardiac structure) of 52/58 patients with classic Fabry disease from the phase 3 clinical trial and extension study, and the Fabry Registry were evaluated. Disease progression rates for patients with low renal involvement (LRI, n=32) or high renal involvement (HRI, n=20) at baseline were assessed. Results 81% of patients (42/52) did not experience any severe clinical event during the treatment interval and 94% (49/52) were alive at the end of the study period. Ten patients reported a total of 16 events. Patients classified as LRI started therapy 13 years younger than HRI (mean 25 years vs 38 years). Mean slopes for estimated glomerular filtration rate for LRI and HRI were −1.89 mL/min/1.73 m2/year and −6.82 mL/min/1.73 m2/year, respectively. Overall, the mean left ventricular posterior wall thickness and interventricular septum thickness remained unchanged and normal. Patients who initiated treatment at age ≥40 years exhibited significant increase in left ventricular posterior wall thickness and interventricular septum thickness. Mean plasma globotriaosylceramide normalised within 6 months. Conclusions This 10-year study documents the effectiveness of agalsidase beta (1 mg/kg/2 weeks) in patients with Fabry disease. Most patients remained alive and event-free. Patients who initiated treatment at a younger age and with less kidney involvement benefited the most from therapy. Patients who initiated treatment at older ages and/or had advanced renal disease experienced disease progression. PMID:25795794

  17. Adverse events of intravenous immunoglobulin infusions: a ten-year retrospective study

    PubMed Central

    Kwong, Shirley L.; Padua, Florecita R.

    2013-01-01

    Background Intravenous immunoglobulin (IVIG) is a biological product with adverse effects that appears to vary considerably among different IVIG preparations. Objectives To describe the adverse events of patients given intravenous immunoglobulin infusions. Method Data was collected on all patients receiving IVIG infusion at a tertiary hospital from January 2001 to December 2010. Descriptive statistics was used. Results 77 patients (45 males, 32 females) received IVIG infusions. Thirty two percent (n = 25) experienced adverse reactions. The most common indication was Kawasaki disease (85.7%) followed by immunodeficiency disorders (7.8%). Majority of the patients were children, with the highest frequency of infusions among those aged 2 to 8 years old (52%). 36 infusions were associated with occurrence of adverse effects. Fever was the most common adverse event (n = 11, 30.6%), followed by rash (n = 8, 22.2%) and chills (n = 7, 19.4%). Other adverse events were cyanosis (n = 3, 8.3%), hypotension (n = 2, 5.6%), hypothermia (n = 2, 5.6%), irritability (n = 1, 2.8%), vomiting (n = 1, 2.8%), and chest pain (n = 1, 2.8%). Adverse events were observed to occur most frequently within 1 to 6 h from onset of IVIG infusion. Among the various IVIG preparations available locally (Gammagard, Kiovig, Gamimune, Veno-S & IV Globulin S), Gammagard was the brand frequently used (50.7%). It also has the most number of adverse events, with 17 out of 41 (41.5%) infusions resulting in adverse reactions. Most of the reactions occurred with fast infusion rates, and clinical manifestations subsided when the rate of infusion was reduced. Conclusion In this study, thirty two percent of patients given IVIG infusions experienced adverse events. Fever was the most common manifestation. Symptoms occurred within 1 to 6 h from onset of infusion, were affected by fast infusion rates, and managed by reducing the rate of infusion. PMID:24260730

  18. Ten-year experience of retrievable inferior vena cava filters in a tertiary referral center

    PubMed Central

    Tse, George; Cleveland, Trevor; Goode, Stephen

    2017-01-01

    PURPOSE A significant proportion of patients undergoing surgery have an increased incidence of acute pulmonary embolus (PE). We analyzed all patients who had a retrievable inferior vena cava (IVC) filter placed preoperatively for PE prophylaxis and investigated the long-term outcomes of the patients who did not have their filter removed. METHODS Patients who underwent retrievable IVC filter insertion and attempted removal were identified from the radiology information systems database in a large tertiary referral university teaching hospital. Results of all clinical investigations (including computed tomography, magnetic resonance imaging, ultrasonography, and plain radiography) while the IVC filters were in situ were reviewed. RESULTS In total, 393 retrievable IVC filters were inserted, 254 with the indication of preoperative thromboembolic prophylaxis. Recurrent PE was reported in five patients (1.9%) despite the IVC filter. Of the 254 retrievable filters inserted prior to surgery, an attempt at retrieval was made in 168 filters (66.1%). Successful retrieval at the first attempt occurred in 143 cases (85.1%), while 25 cases failed or were aborted (14.9%). No attempt at retrieval was made in 86 (33.9%) patients and a significant proportion of these patients had undergone cancer surgery (P < 0.0107). In those patients where there was no attempt at retrieval, there was an association between cancer surgery and a shorter absolute survival time (P < 0.0001). CONCLUSION The majority of attempted filter retrievals were successful, and a proportion of nonretrieved IVC filters are accounted for in patients who underwent cancer surgery and ultimately died with the filter in situ. A departmental protocol is recommended to ensure the filter is removed where appropriate and possible. PMID:28093377

  19. Ten Years Clinical Experience with Partial Ileal Bypass in Management of the Hyperlipidemias

    PubMed Central

    Buchwald, Henry; Moore, Richard B.; Varco, Richard L.

    1974-01-01

    The first partial ileal bypass operation specifically for the reduction of plasma lipids was performed by us in 1963. Since then we have operated upon and followed for more than three months 126 hyperlipidemic patients. Clinical metabolic studies, before and after the procedure, have demonstrated a 60% decrease in cholesterol absorption, a 3.8-fold increase in total fecal steroid excretion, a 5.7-fold increase in cholesterol synthesis, a 3-fold increase in cholesterol turnover, and a one-third decrease in the miscible cholesterol pool. Circulating cholesterol levels have been lowered an average 41.1% from the preoperative but postdietary baseline. An average 53% cholesterol reduction has been achieved from a pretreatment baseline using a combination of dietary and surgical management. Plasma triglycerides have been reduced in primary hypertriglyceridemic patients (type IV) an average of 52.6% from their preoperative but postdietary baseline. One patient died in the hospital and there have been 13 late deaths over the past 10 years. Four cases of postoperative bowel obstruction required reoperation. Diarrhea following partial ileal bypass is, as a rule, transistory and not a significant problem. No appreciable weight loss results from partial ileal bypass, which is an obvious distinction from the results of the far more massive jejuno-ileal bypass procedure for obesity. We have not encountered hepatotoxic, lithogenic, or nephrolithiasis complications in our partial ileal bypass patients. Sixty-nine per cent of our patients with preoperative angina pectoris have postoperative improvement or total remission of this symptom complex. Serial appraisal of followup coronary arteriographic studies offers preliminary evidence for lesion regression. It is concluded that partial ileal bypass is the most effective means for lipid reduction available today; it is obligatory in its actions, safe, and associated with minimal side effects. PMID:4416064

  20. Building Lasting Impact: Ten Years of the Earth to Sky Interagency Partnership

    NASA Astrophysics Data System (ADS)

    Davis, A.; Lacome, B.; Merrick, B.; Morris, J.; Paglierani, R.; Spakoff, S.

    2014-12-01

    Beginning in Fall of 2004, NASA and the National Park Service (NPS) embarked on collaborative work aimed at bringing the wonders of NASA science and education content into the hands of outstanding and highly regarded science "communicators" - interpreters in NPS. What began as a showcase of NASA content delivered in an interpretive workshop has evolved and matured into a long-standing, and growing partnership focused on climate change communication. The partnership has been fruitful and successful, producing a variety of professional development events that have resulted in participants reaching millions of Park and Refuge visitors and thousands of interpreters and educators, with content derived from our courses. Earth to Sky (ETS) now includes the US Fish and Wildlife Service and NOAA, and is working towards establishment of a network of regional networks made up of alumni and their communities. The key to our success has been the careful building and nurturing of the partnership, and its resulting community of practice, beginning with excellent facilitated meetings of the parties involved, and continuing through implementation of best practices in partnership and collaborative work. Project design, development, and execution were accomplished in true partnership with leaders from our intended audience, NPS interpreters, and later USFWS environmental educators. Our partners were fully involved, from the inception of the first workshop design, through its implementation and assessment, to strategic planning for sustainability and all subsequent efforts. ETS can serve as a model of an effective partnership in climate communication efforts, drawing upon the strengths of partners with widely different areas of expertise to produce cohesive work with high impact. We will share the ETS model of partnership, and discuss how this model might be useful as the climate communication community moves towards a more coherent approach to improve climate literacy.

  1. Ten years of anti-smoking programs in Italy: a review.

    PubMed

    Arciti, C; Pistone, M; Persici, P; Barbieri, A; Santi, L

    1995-01-01

    A diverse anti-smoking program for the prevention of cancer and cardiovascular diseases has been ongoing in Italy since 1981, coordinated by the National Cancer Institute of Genoa and the Italian League Against Cancer of Genoa. The program includes several initiatives addressed to different target groups; schoolchildren and teachers, military personnel, doctors and nurses, and women. A preliminary inquiry on the attitudes and habits towards smoking was implemented by the distribution of questionnaires to the various groups involved in the program. An annual school-based anti-smoking program involves about 10,000 students aged four to 18 and their teachers. Meetings are delivered by experts to groups of 20 to 40 students with the aid of specific audiovisual material, which are periodically updated. Additional informative material, leaflets, and posters are distributed to both schoolchildren and teachers. Another educational program on primary prevention of smoking-related health hazards is addressed to military recruits, career soldiers, and medical officers. It consists of several initiatives: training of military doctors and nurses, lectures to military recruits, and distribution of informative material in the barracks. An annual meeting is organized to discuss program implementation and results. Surveys are carried out by distributing an anonymous questionnaire to health professionals in several Italian hospitals to assess the smoking habits of doctors and their attitudes and practices towards counseling patients against smoking. The results show marked differences in smoking habits in the cities under study. Annually since 1983, an updated course is organized and addressed to teachers of primary and secondary schools in Genoa. The aim of the course is to train school personnel and to help them to implement prevention programs in the schools, with the aid of experts in the field of prevention. A series of initiatives are addressed to women at different ages to

  2. Ten Take Home Lessons from the First Ten Years of the CTN and Ten Recommendations for the Future

    PubMed Central

    Carroll, Kathleen M.; Ball, Samuel A.; Jackson, Ron; Martino, Steve; Petry, Nancy M.; Stitzer, Maxine L.; Wells, Elizabeth A.; Weiss, Roger D.

    2011-01-01

    The first ten years of the National Institute on Drug Abuse’s Clinical Trials Network (CTN) yielded a wealth of data on the effectiveness of a number of behavioral, pharmacologic, and combined approaches in community based settings. As an introduction to this Special Issue on the CTN, we summarize some of the methodological contributions and lessons learned from the behavioral trials conducted during its first ten years, including the capacity and enormous potential of this national research infrastructure; contributions to the methodology of effectiveness research; new insights from secondary analyses; the extent to which approaches with strong evidence bases, such as contingency management, extend their effectiveness to real world clinical settings; new data on ‘standard treatment’ as actually practiced in community programs, the extent to which retention remains a major issue in the field; important data on the safety of specific behavioral therapies for addiction; and heightened the importance of continued sustained attention to bridging the gap between treatment and research. Possible areas of focus for the CTN’s future include defining common outcome measures to be used in treatment outcome studies for illicit drugs; incorporating performance indicators and measures of clinical significance; conducting comparative outcome studies; contributing to the understanding of effective treatments of comorbidity; reaching underserved populations; building implementation science; understanding long-term outcomes of current treatments and sustaining treatment effects; and conducting future trials more efficiently. PMID:21854269

  3. Ten-Year Longitudinal Trajectories of Older Adults’ Basic and Everyday Cognitive Abilities

    PubMed Central

    Yam, Anna; Gross, Alden; Prindle, John; Marsiske, Michael

    2014-01-01

    Objective To examine the longitudinal trajectories of everyday cognition and longitudinal associations with basic (i.e., laboratory and experimentally measured) cognitive abilities, including verbal memory, inductive reasoning, visual processing speed, and vocabulary. Method Participants were healthy older adults drawn from the no-treatment control group (N = 698) of the ACTIVE randomized trial, and were assessed at baseline and 1, 2, 3, 5, and 10 years later. Analyses were conducted using latent growth models. Results Modeling revealed an overall inverted “U” shape (quadratic) trajectory across cognitive domains. Among basic cognitive predictors, level and slope in reasoning demonstrated the closest association to level and slope of everyday cognition, and accounted for most of the individual differences in linear gain in everyday cognition. Conclusions Everyday cognition is not buffered against decline, and is most closely related to inductive reasoning in healthy older adults. To establish the clinical utility of everyday cognitive measures, future research should examine these associations in samples with more cognitive impairment. PMID:24885451

  4. Ten Years of Land Cover Change on the California Coast Detected using Landsat Satellite Image Analysis

    NASA Technical Reports Server (NTRS)

    Potter, Christopher S.

    2013-01-01

    Landsat satellite imagery was analyzed to generate a detailed record of 10 years of vegetation disturbance and regrowth for Pacific coastal areas of Marin and San Francisco Counties. The Landsat Ecosystem Disturbance Adaptive Processing System (LEDAPS) methodology, a transformation of Tasseled-Cap data space, was applied to detected changes in perennial coastal shrubland, woodland, and forest cover from 1999 to 2009. Results showed several principal points of interest, within which extensive contiguous areas of similar LEDAPS vegetation change (either disturbed or restored) were detected. Regrowth areas were delineated as burned forest areas in the Point Reyes National Seashore (PRNS) from the 1995 Vision Fire. LEDAPS-detected disturbance patterns on Inverness Ridge, PRNS in areas observed with dieback of tanoak and bay laurel trees was consistent with defoliation by sudden oak death (Phytophthora ramorum). LEDAPS regrowth pixels were detected over much of the predominantly grassland/herbaceous cover of the Olema Valley ranchland near PRNS. Extensive restoration of perennial vegetation cover on Crissy Field, Baker Beach and Lobos Creek dunes in San Francisco was identified. Based on these examples, the LEDAPS methodology will be capable of fulfilling much of the need for continual, low-cost monitoring of emerging changes to coastal ecosystems.

  5. Stainless steel wire mesh cranioplasty: ten years' experience with 183 patients (100 followed up).

    PubMed

    Datti, R; Cavagnaro, G; Camici, S

    1985-01-01

    We have executed 183 cranioplasties in order to repair cranial defects using stainless steel wire mesh over a period of a decade, using Gardner's technique with minor modifications. The follow-up was possible in 100 patients and it ranged from 4 to 134 months, with an average of 64.1 months (5.3 years). Among these, 8 patients developed postoperative complications (8%): 7 needed cranioplasty remotion (7%) and 1 needed cranioplasty revision without remotion (1%). The causes of morbidity were due to: infection (3%), CSF leak (1%), haematoma (1%), skin local soaking (1%), posttraumatic plastic dislodgement (2%). Our total morbidity rate (8%) may compare with that resulting from the use of different materials such as alloplastics (6-12%), osteoplastics (until 40%) and miscellaneous (5.5%). The group in which cranioplasty was done within six months following the first operation had our highest complication rate (18.2%). In our experience the stainless steel wire mesh was shown to be an effective material to repair cranial defects.

  6. Ten Years Long Near-infrared Variable Star Survey In The Magellanic Clouds

    NASA Astrophysics Data System (ADS)

    Ita, Yoshifusa

    2012-05-01

    We started the near-infrared variable star survey in the Large and Small Magellanic Clouds in December 2000. Since then, we keep monitoring an area of 3 square degrees along the bar in the LMC, and also an area of 1 square degree in the central part of the SMC until the end of 2010. In the 10 years, we observed these areas about 80-90 and 100-110 times for LMC and SMC, respectively. Our survey is the world's first and the only one that provides near-infrared time-series data with such a long baseline and of such a large scale. We will show some preliminary results from the survey in the poster. This work is supported by the Grant-in-Aid for Encouragement of Young Scientists (B) No.21740142 from the Ministry of Education, Culture, Sports, Science and Technology of Japan. This work is also supported by the Brain Circulation Program (R2301) by Japan Society for the Promotion of Science.

  7. Multi-criteria decision analysis in environmental sciences: ten years of applications and trends.

    PubMed

    Huang, Ivy B; Keisler, Jeffrey; Linkov, Igor

    2011-09-01

    Decision-making in environmental projects requires consideration of trade-offs between socio-political, environmental, and economic impacts and is often complicated by various stakeholder views. Multi-criteria decision analysis (MCDA) emerged as a formal methodology to face available technical information and stakeholder values to support decisions in many fields and can be especially valuable in environmental decision making. This study reviews environmental applications of MCDA. Over 300 papers published between 2000 and 2009 reporting MCDA applications in the environmental field were identified through a series of queries in the Web of Science database. The papers were classified by their environmental application area, decision or intervention type. In addition, the papers were also classified by the MCDA methods used in the analysis (analytic hierarchy process, multi-attribute utility theory, and outranking). The results suggest that there is a significant growth in environmental applications of MCDA over the last decade across all environmental application areas. Multiple MCDA tools have been successfully used for environmental applications. Even though the use of the specific methods and tools varies in different application areas and geographic regions, our review of a few papers where several methods were used in parallel with the same problem indicates that recommended course of action does not vary significantly with the method applied.

  8. Ecological impacts of genetically modified crops: ten years of field research and commercial cultivation.

    PubMed

    Sanvido, Olivier; Romeis, Jörg; Bigler, Franz

    2007-01-01

    The worldwide commercial cultivation of genetically modified (GM) crops has raised concerns about potential adverse effects on the environment resulting from the use of these crops. Consequently, the risks of GM crops for the environment, and especially for biodiversity, have been extensively assessed before and during their commercial cultivation. Substantial scientific data on the environmental effects of the currently commercialized GM crops are available today. We have reviewed this scientific knowledge derived from the past 10 years of worldwide experimental field research and commercial cultivation. The review focuses on the currently commercially available GM crops that could be relevant for agriculture in Western and Central Europe (i.e., maize, oilseed rape, and soybean), and on the two main GM traits that are currently commercialized, herbicide tolerance (HT) and insect resistance (IR). The sources of information included peer-reviewed scientific journals, scientific books, reports from regions with extensive GM crop cultivation, as well as reports from international governmental organizations. The data available so far provide no scientific evidence that the cultivation of the presently commercialized GM crops has caused environmental harm. Nevertheless, a number of issues related to the interpretation of scientific data on effects of GM crops on the environment are debated controversially. The present review highlights these scientific debates and discusses the effects of GM crop cultivation on the environment considering the impacts caused by cultivation practices of modern agricultural systems.

  9. Ten Years of Cloud Properties from MODIS: Global Statistics and Use in Climate Model Evaluation

    NASA Technical Reports Server (NTRS)

    Platnick, Steven E.

    2011-01-01

    The NASA Moderate Resolution Imaging Spectroradiometer (MODIS), launched onboard the Terra and Aqua spacecrafts, began Earth observations on February 24, 2000 and June 24,2002, respectively. Among the algorithms developed and applied to this sensor, a suite of cloud products includes cloud masking/detection, cloud-top properties (temperature, pressure), and optical properties (optical thickness, effective particle radius, water path, and thermodynamic phase). All cloud algorithms underwent numerous changes and enhancements between for the latest Collection 5 production version; this process continues with the current Collection 6 development. We will show example MODIS Collection 5 cloud climatologies derived from global spatial . and temporal aggregations provided in the archived gridded Level-3 MODIS atmosphere team product (product names MOD08 and MYD08 for MODIS Terra and Aqua, respectively). Data sets in this Level-3 product include scalar statistics as well as 1- and 2-D histograms of many cloud properties, allowing for higher order information and correlation studies. In addition to these statistics, we will show trends and statistical significance in annual and seasonal means for a variety of the MODIS cloud properties, as well as the time required for detection given assumed trends. To assist in climate model evaluation, we have developed a MODIS cloud simulator with an accompanying netCDF file containing subsetted monthly Level-3 statistical data sets that correspond to the simulator output. Correlations of cloud properties with ENSO offer the potential to evaluate model cloud sensitivity; initial results will be discussed.

  10. [Surgery of bronchiectasis: what have changed in the last ten years?].

    PubMed

    António, Carla; Pinto, Nelson; Bihun, Vyacheslav; Bernardo, João; Antunes, Manuel

    2010-01-01

    Bronchiectasis is defined as chronic abnormal dilatation and distortion of the bronchi. Surgery continues to be play an important role in the treatment of this disease especially in focal disease which is both curative. The objective of this study is to characterize the patients who underwent surgical resection of bronchiectasis in 10 years and compare them with patients operated by the same pathology in the previous 10 years. We conducted a review of cases of 78 patients operated in the 2000 ' s and the results were compared with those obtained in the study by the same professional service, referring to the previous decade. We assessed sex, age, symptoms, number of years with symptoms, complementary exams performed prior to surgery, indications for surgery, previous pulmonary diseases, location of bronchiectasis, type of surgical approach, number of hospitalization days and complications of surgery. In the last decade a smaller number of patients with bronchiectasis ( 78 versus 119 ) were submitted to thoracic surgery. In both groups the right lung and the lower lobes were the most affected and the majority of patients was submitted to lobectomy. In the last decade a lower percentage of complications was registed ( 6.4 %, versus 15.0 % (. The surgery was considered to be curative in 94.9 % and only 91 % in the 90 ' s. This study would support the idea that the surgery of bronchiectasis continues to be an excellent alternative to the treatment of localized forms of the disease and its complications.

  11. A Ten-Year Molecular Survey on Parvoviruses Infecting Carnivores in Bulgaria.

    PubMed

    Filipov, C; Desario, C; Patouchas, O; Eftimov, P; Gruichev, G; Manov, V; Filipov, G; Buonavoglia, C; Decaro, N

    2016-08-01

    Parvoviruses represent the most important infectious agents that are responsible for severe to fatal disease in carnivores. This study reports the results of a 10-year molecular survey conducted on carnivores in Bulgaria (n = 344), including 262 dogs and 19 cats with gastroenteritis, and 57 hunted wild carnivores. Real-time polymerase chain reaction (qPCR), followed by virus characterization by minor groove binder (MGB) probe assays, detected 216 parvovirus positive dogs with a predominance of canine parvovirus type 2a (CPV-2a, 79.17%) over CPV-2b (18.52%) and CPV-2c (2.31%). Rottweilers and German shepherds were the most frequent breeds among CPV-positive pedigree dogs (n = 96). Eighteen cats were found to shed parvoviruses in their faeces, with most strains being characterized as FPLV (n = 17), although a single specimen tested positive for CPV-2a. Only two wild carnivores were parvovirus positive, a wolf (Canis lupus) and a red fox (Vulpes vulpes), both being infected by CPV-2a strains.

  12. Racial and nonracial discrimination and smoking status among South African adults ten years after apartheid

    PubMed Central

    Dutra, Lauren M; Williams, David R; Kawachi, Ichiro; Okechukwu, Cassandra A

    2014-01-01

    Background Despite a long history of discrimination and persisting racial disparities in smoking prevalence, little research exists on the relationship between discrimination and smoking in South Africa. Methods This analysis examined chronic (day to day) and acute (lifetime) experiences of racial and nonracial (e.g., age, gender, or physical appearance) discrimination and smoking status among respondents to the South Africa Stress and Health Study (SASH). Logistic regression models were constructed using SAS-Callable SUDAAN. Results Both chronic racial discrimination (RR=1.45, 95%CI: 1.14–1.85) and chronic nonracial discrimination (RR=1.69, 95%CI: 1.37–2.08) predicted a higher risk of smoking, but neither type of acute discrimination did. Total (sum of racial and nonracial) chronic discrimination (RR=1.46, 95%CI: 1.20–1.78) and total acute discrimination (RR=1.28, 95%CI: 1.01–1.60) predicted a higher risk of current smoking. Conclusions Racial and nonracial discrimination may be related to South African adults’ smoking behavior, but this relationship likely varies by the timing and frequency of these experiences. Future research should use longitudinal data to identify the temporal ordering of the relationships studied, include areas outside of South Africa to increase generalizability, and consider the implications of these findings for smoking cessation approaches in South Africa. PMID:24789604

  13. Ten year environmental test of glass fiber/epoxy pressure vessels

    NASA Technical Reports Server (NTRS)

    Faddoul, J. R.

    1985-01-01

    By the beginning of the 1970's composite pressure vessels had received a significant amount of development effort, and applications were beginning to be investigated. One of the first applications grew out of NASA Johnson Space Center efforts to develop a superior emergency breathing system for firemen. While the new breathing system provided improved wearer comfort and an improved mask and regulator, the primary feature was low weight which was achieved by using a glass fiber reinforced aluminum pressure vessel. Part of the development effort was to evaluate the long term performance of the pressure vessel and as a consequence, some 30 bottles for a test program were procured. These bottles were then provided to NASA Lewis Research Center where they were maintained in an outdoor environment in a pressurized condition for a period of up to 10 yr. During this period, bottles were periodically subjected to cyclic and burst testing. There was no protective coating applied to the fiberglass/epoxy composite, and significant loss in strength did occur as a result of the environment. Similar bottles stored indoors showed little, if any, degradation. This report contains a description of the pressure vessels, a discussion of the test program, data for each bottle, and appropriate plots, comparisons, and conclusions.

  14. Ten years of hospitalisation for oral health-related conditions in Western Australia: an unjust dichotomy.

    PubMed

    Kruger, Estie; Tennant, Marc

    2016-01-01

    The objective of this study was: (1) to examine the demographics of in-patient oral health care by Aboriginal status; (2) to identify the mix of oral conditions by Aboriginal status; and (3) to describe trends over a 10-year period, comparing Aboriginal and non-Aboriginal groups. Hospitalisation data were obtained from the Western Australian Morbidity Data System (HMDS). The principal diagnosis, as classified by the International Classification of Disease (ICD-10AM), was obtained for every episode for adult patients who were discharged from all hospitals in Western Australia (WA) for the financial years 1999-2000 to 2008-09. Results indicated that more than 130000 persons were admitted to hospitals in WA over 10 years, for oral health-related conditions, at a direct cost of more than $400million. Most of those admitted were younger than 30 years, and 2.8% of all those admitted were Aboriginal people. Aboriginal people were admitted at significantly higher rates, for a very different mix of conditions, they were mostly from younger age groups, were mostly from very remote and the most disadvantaged areas and were almost all uninsured, compared with non-Aboriginal people. Hospital admissions for oral health-related conditions, as well as the mix of conditions that drive these hospitalisations, are strongly divided across social, racial and geographic variables, and remain a burden to the health-care system.

  15. Ten years' work on the World Organisation for Animal Health (OIE) Worldwide Animal Disease Notification System.

    PubMed

    Jebara, Karim Ben; Cáceres, Paula; Berlingieri, Francesco; Weber-Vintzel, Laure

    2012-12-01

    This article gives an overview of the World Organisation for Animal Health (OIE) Worldwide Animal Disease Notification System and highlights the major achievements during the past decade. It describes the different types of disease notification reports received and processed by the OIE. It also evaluates the three strategies implemented by the OIE in the recent years aimed at improving disease notification: introduction and use of a secure online notification system World Animal Health Information System (WAHIS) and its database interface World Animal Health Information Database (WAHID); implementation of active search and verification procedures for non-official information; and enhanced building of capacity for animal disease notification to the OIE by Members Countries. The improvements are evidenced by the increasing number of reports submitted on an annual basis and the reduction in submission time together with an improvement in the quality and quantity of the immediate notifications and follow-up reports, six-monthly and annual reports submitted by Veterinary Authorities. In the recent years, the OIE's notification system provides an early warning system more sensitive and global. Consequently, there is a greater knowledge of animal diseases' distribution worldwide. As a result, it is possible to ensure better prevention, more accurate risk assessment and evaluation by diminishing the spread of known or newly emerging pathogens.

  16. Ten years of anti-HPV vaccinations: what do we know?

    PubMed Central

    Basta, Antoni; Kotarski, Jan; Markowska, Janina; Paszkowski, Tomasz; Dębski, Romuald; Rokita, Wojciech; Kędzia, Witold; Kiszka, Krystyna

    2016-01-01

    Human papillomavirus (HPV) is one of the most important carcinogens in humans. Vaccines against HPV are now considered the first anti-cancer vaccinations. Since 2007, in many developed countries, there have been recommendations present for preventive vaccines against HPV. At present, the degree of implementation of these recommendations depends on a number of country-specific factors such as the health care system organization or the ways of funding. HPV vaccines are primarily to prevent the development of cervical cancer and other genital cancers. Therefore, only their long-term effectiveness can be measured, when a correspondingly large cohort of vaccinated teenagers reaches the age of the greatest incidence of these cancers. However, great care should be taken in assessing the results of vaccinations due to the possibility of misinterpretation and possible erroneous data. Undoubtedly, teenagers are the target population of HPV vaccines. However, vaccinating young sexually active women is also justified from an individual point of view. A 9-valent vaccine has been registered in the USA and in Europe – including Poland – as one of the three preventive vaccines. It is recommended to vaccinate women between 13 and 26 and men between 13 and 21, previously unvaccinated. It is also recommended to vaccinate men aged 26 years or less who have sexual relations with other men and people with reduced immunity, including HIV-positive people who have not been vaccinated previously. PMID:27980529

  17. Ten years of international collaboration in biomedical informatics and beyond: the AMAUTA program in Peru

    PubMed Central

    Fuller, Sherrilynne; Garcia, Patricia J; Holmes, King K; Kimball, Ann Marie

    2010-01-01

    Well-trained people are urgently needed to tackle global health challenges through information and communication technologies. In this report, AMAUTA, a joint international collaborative training program between the Universidad Peruana Cayetano Heredia and the University of Washington, which has been training Peruvian health professionals in biomedical and health informatics since 1999, is described. Four short-term courses have been organized in Lima, offering training to more than 200 graduate-level students. Long-term training to masters or doctorate level has been undertaken by eight students at the University of Washington. A combination of short-term and long-term strategies was found to be effective for enhancing institutional research and training enterprise. The AMAUTA program promoted the development and institution of informatics research and training capacity in Peru, and has resulted in a group of trained people playing important roles at universities, non-government offices, and the Ministry of Health in Peru. At present, the hub is being extended into Latin American countries, promoting South-to-South collaborations. PMID:20595317

  18. Surgical Management in Elderly Patients with Tuberculous Spondylodiscitis: Ten Year Mortality Audit Study

    PubMed Central

    Kothari, Manish Kundanmal; Tikoo, Agnivesh; Nene, Abhay Madhusudan

    2016-01-01

    Study Design Retrospective study. Purpose To evaluate the factors affecting immediate postoperative mortality in elderly patients with tuberculous spondylodiscitis. Overview of Literature Treatment of spinal tuberculosis in the elderly involves consideration of age and co-morbidities, and often leads to an extended conservative management. Surgical intervention in these patients becomes a complex decision. There are no studies on risk factors of mortality in surgically treated elderly with tuberculous spondylodiscitis. Methods Two hundred and seventy-six patients with spondylodiscitis were operated between 2005 and 2015. 20 consecutive patients over 70 years of age with and proven tuberculosis who met the inclusion/exclusion criteria were included. Demographic, clinical and radiological profile data with operative details of instrumentation, blood loss, surgical duration, and mortality were noted. There were 20 patients (6 males, 14 females) with a mean age of 73.5 years. The patients were divided into those with mortality (M) and those who survived (non-mortality, NM). Various variables were statistically tested for immediate postoperative medical complications and mortality. Results There were four mortalities (20%). Age, sex, number of medical co-morbidities, American Society of Anaesthesiologists grade, Frankel grade C or worse, number of vertebrae involved, number of levels fused, blood loss and operative time did not have statistically significant impact on immediate postoperative mortality. Only preoperative immobility duration was statistically higher in the M group (p=0.016) than in the NM group. Conclusions Preoperative immobility is associated with immediate postoperative mortality in elderly patients with spinal tuberculosis undergoing surgery. The findings identify preoperative immobility as a risk factor for mortality, which could contribute to a more detailed prognostic discussion between surgeon and patient before surgery. PMID:27790320

  19. Ten-Year Cleft Surgery in Nepal: Achievements and Lessons Learned for Better Cleft Care Abroad

    PubMed Central

    Pape, Hans-Dieter; Koch, Heribert; Koller, Michael

    2016-01-01

    Background: Cleft lip and palate surgery abroad is devoid of global consensus regarding standards of therapy, follow-up, and outcome. Cleft surgery in Nepal during a 10-year sustained program provided the opportunity to inform on the need for such standards. Methods: Medical records were evaluated from the cleft clinic at Sushma Koirala Memorial Hospital, Sankhu, Kathmandu, Nepal, from 1997 to 2007. Four groups were identified for analysis: total cohort, total surgical cohort (TSC), primary program patients (PPP; patients had not been operated on before), and nonprimary program patients (non-PPP; patients operated on elsewhere before). Patient demographics, diagnostic, primary and secondary surgery (corrective surgery), and follow-up were evaluated. Results: One thousand forty-five patients were eligible for surgery. Three hundred twenty-three of 1,045 patients (30.9%) did not seek treatment, although scheduled for surgery. One thousand two hundred one procedures were performed in 722 patients [TSC; 845 PPP (70.4%); 356 non-PPP (29.64%)]. Corrective procedures were performed in 257 of 1,201 [3.5% (30 of 845 procedures in 509 patients) PPP vs 63.7% (227 of 356 procedures in 213 patients) non-PPP]. One hundred six lips were completely reoperated on (1 PPP vs 105 non-PPP), and 42 palates underwent a total revision (5 PPP vs 37 non-PPP). The surgical outcome of the TSC group in terms of complication rate was similar to the one in developed countries. Conclusions: The high rate of corrective surgery reveals the need for global regulatory mechanisms and the need for nongovernmental organizations to introduce strategies for delivering sustained cleft care until achieving full rehabilitation. The World Health Organization should establish standards for cleft care delivered in less developed countries. PMID:27579235

  20. Ten-Year Review of Major Birth Defects in VLBW Infants

    PubMed Central

    Hansen, Nellie I.; Shankaran, Seetha; Bell, Edward F.; Boghossian, Nansi S.; Murray, Jeffrey C.; Laptook, Abbot R.; Walsh, Michele C.; Carlo, Waldemar A.; Sánchez, Pablo J.; Van Meurs, Krisa P.; Das, Abhik; Hale, Ellen C.; Newman, Nancy S.; Ball, M. Bethany; Higgins, Rosemary D.; Stoll, Barbara J.

    2013-01-01

    OBJECTIVE: Birth defects (BDs) are an important cause of infant mortality and disproportionately occur among low birth weight infants. We determined the prevalence of BDs in a cohort of very low birth weight (VLBW) infants cared for at the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network (NRN) centers over a 10-year period and examined the relationship between anomalies, neonatal outcomes, and surgical care. METHODS: Infant and maternal data were collected prospectively for infants weighing 401 to 1500 g at NRN sites between January 1, 1998, and December 31, 2007. Poisson regression models were used to compare risk of outcomes for infants with versus without BDs while adjusting for gestational age and other characteristics. RESULTS: A BD was present in 1776 (4.8%) of the 37 262 infants in our VLBW cohort. Yearly prevalence of BDs increased from 4.0% of infants born in 1998 to 5.6% in 2007, P < .001. Mean gestational age overall was 28 weeks, and mean birth weight was 1007 g. Infants with BDs were more mature but more likely to be small for gestational age compared with infants without BDs. Chromosomal and cardiovascular anomalies were most frequent with each occurring in 20% of affected infants. Mortality was higher among infants with BDs (49% vs 18%; adjusted relative risk: 3.66 [95% confidence interval: 3.41–3.92]; P < .001) and varied by diagnosis. Among those surviving >3 days, more infants with BDs underwent major surgery (48% vs 13%, P < .001). CONCLUSIONS: Prevalence of BDs increased during the 10 years studied. BDs remain an important cause of neonatal morbidity and mortality among VLBW infants. PMID:23733791

  1. Changing trends in corneal graft surgery: a ten-year review

    PubMed Central

    de Sanctis, Ugo; Alovisi, Camilla; Bauchiero, Luigi; Caramello, Guido; Girotto, Gianfranco; Panico, Claudio; Vinai, Luisa; Genzano, Federico; Amoroso, Antonio; Grignolo, Federico

    2016-01-01

    AIM To review indications and corneal tissue use for penetrating and lamellar surgery between 2002 and 2011. METHODS The surgical reports of corneal grafts performed during 2002-2011, using tissues supplied by the Eye Bank of Piedmont (Italy), were reviewed retrospectively. Patient demographic data, date of intervention, indication for surgery, and surgical technique used were recorded. Surgical techniques included penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) and endothelial keratoplasty (EK). The χ2 test was used to compare the distribution of indications and types of surgical technique used, for corneal grafts done during 2002-2006 versus those done during 2007-2011. RESULTS The number of corneal grafts increased by 30.7% from 2002-2006 to 2007-2011 (from 1567 to 2048). Comparing the two periods, both main indications and surgical techniques changed significantly. In 2007-2011, the proportion of interventions for aphakic/pseudophakic bullous keratopathy (from 16.8% to 21.3%), graft failure (from 16.4% to 19.1%) and Fuchs endothelial dystrophy (from 12.8% to 16.7%) all increased significantly (P<0.05), while those for keratoconus decreased significantly (from 35.6% to 27.3%; P<0.001). In 2007-2011, the proportion of PK decreased significantly (from 92.4% to 57.2%; P<0.001) while that of EK and DALK went from 0.4% to 30.2% (P<0.001) and from 7.2% to 12.6% (P<0.001) respectively. CONCLUSION During 2002-2011 the number of interventions increased significantly for corneal endothelial diseases and graft failure. The growing demand for interventions for these diseases corresponded to the widespread adoption of EK techniques. The use of DALK also increased, but more moderately than EK procedures. PMID:26949609

  2. Residential relocations among older people over the course of more than ten years

    PubMed Central

    Buurman, Bianca M.; Trentalange, Mark; Nicholson, Nicholas; McGloin, Joanne M.; Gahbauer, Evelyne A.; Allore, Heather G.; Gill, Thomas M.

    2014-01-01

    Objective To describe the rates of residential relocations over the course of 10.5 years and evaluate differences in these relocation rates according to gender and decedent status. Design Prospective, longitudinal study with monthly telephone follow-up for up to 126 months. Setting Greater New Haven, Connecticut. Participants 754 persons, aged 70 years or older, who were initially community-living and nondisabled in their basic activities of daily living. Measurements Residential location was assessed during monthly interviews and included: community, assisted living facility (AL) and nursing home (NH). A residential relocation was defined as a change of residential location for at least one week and included relocations within (e.g. community-community) or between (community-assisted living) locations. We calculated the rates of relocations/1000 patient-months and evaluated differences by gender and decedent status. Results Sixty-six percent of participants had at least one residential relocation (range 0–12). Women had lower rates of relocations from NH to community (rate ratio (RR) 0.59, p=.02); otherwise, there were no gender differences. Decedents had higher rates of relocation from community to AL (RR 1.71, p=0.002), from community to NH (RR 3.64, p<.001), between ALs (RR 3.65, p<.001) and from AL to NH (RR 2.5, p<0.001). In decedents, relocations from community to NH (RR 3.58, p<.001) and from AL to NH (RR 3.3, p<.001) were most often observed in the last year of life. Conclusions A majority of older people relocated at least once during 10.5 years follow-up. Women had lower rates of relocation from NH to community. Decedents were more likely to relocate to a residential location providing a higher level of assistance, compared with non-decedents. Residential relocations were most common in the last year of life. PMID:24794829

  3. Ten-Year Recurrence Rates in Young Women With Breast Cancer by Locoregional Treatment Approach

    SciTech Connect

    Beadle, Beth M.; Woodward, Wendy A. Tucker, Susan L.; Outlaw, Elesyia D.; Allen, Pamela K.; Oh, Julia L.; Strom, Eric A.; Perkins, George H.; Tereffe, Welela; Yu, T.-K.; Meric-Bernstam, Funda; Litton, Jennifer K.; Buchholz, Thomas A.

    2009-03-01

    Purpose: Young women with breast cancer have higher locoregional recurrence (LRR) rates than older patients. The goal of this study is to determine the impact of locoregional treatment strategy, breast-conserving therapy (BCT), mastectomy alone (M), or mastectomy with adjuvant radiation (MXRT), on LRR for patients 35 years or younger. Methods and Materials: Data for 668 breast cancers in 652 young patients with breast cancer were retrospectively reviewed; 197 patients were treated with BCT, 237 with M, and 234 with MXRT. Results: Median follow-up for all living patients was 114 months. In the entire cohort, 10-year actuarial LRR rates varied by locoregional treatment: 19.8% for BCT, 24.1% for M, and 15.1% for MXRT (p = 0.05). In patients with Stage II disease, 10-year actuarial LRR rates by locoregional treatment strategy were 17.7% for BCT, 22.8% for M, and 5.7% for MXRT (p = 0.02). On multivariate analysis, M (hazard ratio, 4.45) and Grade III disease (hazard ratio, 2.24) predicted for increased LRR. In patients with Stage I disease, there was no difference in LRR rates based on locoregional treatment (18.0% for BCT, 19.8% for M; p = 0.56), but chemotherapy use had a statistically significant LRR benefit (13.5% for chemotherapy, 27.9% for none; p = 0.04). Conclusions: Young women have high rates of LRR after breast cancer treatment. For patients with Stage II disease, the best locoregional control rates were achieved with MXRT. For patients with Stage I disease, similar outcomes were achieved with BCT and mastectomy; however, chemotherapy provided a significant benefit to either approach.

  4. Maternal and Neonatal Effects of Substance Abuse during Pregnancy: Our Ten-year Experience

    PubMed Central

    Roje, Damir; Vučnović, Zoran; Capkun, Vesna; Bucat, Marija; Banović, Ivo

    2008-01-01

    Purpose The aim of the study was to assess perinatal outcome of pregnancy burdened with maternal addiction in comparison with an unselected population from a European transition country. Materials and Methods Data on pregnancies complicated by illicit drug abuse (n = 85) managed during a 10-year period (1997 - 2007) at Split University Hospital were analyzed. Data on the type of drug, course of gestation and labor, and on perinatal outcome were considered. Data on all non-dependence pregnancies recorded during the study period were used as a control group. Results During the study period, there were 85 dependence-complicated pregnancies (0.2%). Use of heroin alone during pregnancy was recorded in 51 women (50%), methadone alone in 6 (7%), and a combination of heroin and methadone in 9 (11%). Premature delivery was significantly more common in the group of pregnant addicts (21% vs. 6%); 49% of pregnant addicts were carriers of hepatitis C virus (HCV) and 14% of hepatitis B virus (HBV). Neonatal abstinence syndrome developed in 61 infants (7%) born to addicted mothers. There were 4 cases (4.6%) of early neonatal death; 7 neonates had 5-minute Apgar score ≤ 7 (8%); 29 neonates had low birth weight for age (33%); and 7 neonates had congenital anomalies (8%). The risk of various congenital anomalies was 3-fold in the group of children born to addicted mothers. Conclusion Addiction pregnancies present a small but high-risk group according to perinatal outcome. Appropriate obstetric and neonatal care can reduce the rate of complications in these pregnancies and improve perinatal outcome. PMID:18972589

  5. Primary Dental Care 1994-2004: the first ten years. A chronology.

    PubMed

    Renson, Ted

    2004-10-01

    The prime purpose of a professional journal is to keep its readers informed of changes of importance affecting the practise of that profession. That is the criterion that I have applied in producing this chronology of the papers that have been published in Primary DENTAL CARE during the past decade. The ambition which has guided me since I received the invitation to carry out this review is a simple one: to include as much as may generally be found useful by general dental practitioners (GDPs), who form the bulk of our readership. In 1789 the English philosopher Jeremy Bentham extolled the virtues of utility for mankind when he declared that 'the greatest happiness of the greatest number is the foundation of morals and legislation'. The contributors that I have included, by contrast, think of their utilitarianism as striving after the most practical. The principal purpose of this chronology is to achieve a summary, without weighing causes or consequences. From past experience, an outstanding virtue of such an aggregated record is that it can inspire fresh patterns of thought and thus encourage the submission of manuscripts as a result of those thoughts. I can think of scarcely any facet of the general practice of dentistry that has not been touched upon, for the most part authoritatively. I hope that these brief aide-memoires may persuade old readers to return to those articles of particular interest to them and that new readers will feel informed about past papers. Every issue of the journal to date has been reviewed. Dates, volume and issue numbers and principal authors' names are all included. With these identifying features any paper, to which reference is made, may be quickly found. It would be manifestly absurd to use precious space on a formal listing of more than 250 references and this listing has, therefore, been omitted.

  6. Ten years of measured UV Index from the Spanish UVB Radiometric Network.

    PubMed

    Utrillas, M P; Marín, M J; Esteve, A R; Estellés, V; Gandía, S; Núnez, J A; Martínez-Lozano, J A

    2013-08-05

    An analysis is made of the UV Index (UVI) obtained from the ultraviolet erythemal solar radiation (UVER) data measured by the Spanish UVB Radiometric Network between the years 2000 and 2009. Previously, the daily UVI has been evaluated using two different criteria: (a) the value corresponding to solar noon; and (b) the daily maximum value. The mean percentage of agreement is 92% if we consider the cases for which the difference is zero or one UVI unit. These results are similar to those obtained in a previous work where only 2 years were analyzed. In all the stations the UVI reaches very high values (8-10) in spring-summer, and the very high and extreme (≥ 11) UVI values are more dependent on the continental effect than on the latitude effect. From the UVI values it is possible to classify the stations into four groups: Coastal stations, Continental stations (more than 200 km from the coast), Southern stations (Coastal stations but with similar values of UVI as the Continental ones due to their low latitude) and Canary Islands stations (1400 km southwest from the Iberian Peninsula thus lower latitude). The monthly mean maximum of UVI is reached in July due to the annual evolution of the total ozone column. This value corresponds, for a skin phototype II, to three times the minimal erythemal dose (MED) in an hour in a Coastal station, 3.5 MEDs in an hour measured in a Continental or Southern station and up five MEDs in an hour in the Izaña station (Canary Islands). The cumulative dose on a horizontal plane over an average year has been calculated for each station. More than 40% of the annual dose is received in summer, about 35% in spring, more than 11% in autumn and less than 10% in winter except for the stations in the Canary Islands where the difference between seasons is less significant.

  7. Ten-Year Experience of Cutaneous and/or Subcutaneous Infections Due to Coelomycetes in France

    PubMed Central

    Guégan, Sarah; Garcia-Hermoso, Dea; Sitbon, Karine; Ahmed, Sarah; Moguelet, Philippe; Dromer, Françoise; Lortholary, Olivier

    2016-01-01

    Background. Coelomycetes are rarely but increasingly reported in association with human infections involving mostly skin and subcutaneous tissues, both in immunocompetent and immunocompromised patients. Coelomycetes constitute a heterogeneous group of filamentous fungi with distinct morphological characteristics in culture, namely an ability to produce asexual spores within fruit bodies. Methods. We included all cases of proven primary cutaneous and/or subcutaneous infections due to coelomycetes received for identification at the French National Reference Center for Invasive Mycoses and Antifungals between 2005 and 2014. Eumycetoma, chromoblastomycosis, and disseminated infections were excluded. Results. Eighteen cases were analyzed. The median age was 60.5 years. In all cases, patients originated from tropical or subtropical areas. An underlying immunodepression was present in 89% of cases. Cutaneous and/or subcutaneous lesions, mainly nodules, abscesses, or infiltrated plaques, were observed in distal body areas. Isolates of different genera of coelomycetes were identified: Medicopsis (6), Paraconiothyrium (3), Gloniopsis (3), Diaporthe (3), Peyronellaea (2), Lasiodiplodia (1). Lesion treatment consisted of complete (10) or partial (2) surgical excision and/or the use of systemic antifungal therapy, namely voriconazole (5) and posaconazole (4). Literature review yielded 48 additional cases of cutaneous and/or subcutaneous infections due to coelomycetes. Conclusions. Infectious diseases physicians should suspect coelomycetes when observing cutaneous and/or subcutaneous infections in immunocompromised hosts from tropical areas; a sequence-based approach is crucial for strains identification but must be supported by consistent phenotypic features; surgical treatment should be favored for solitary, well limited lesions; new triazoles may be used in case of extensive lesions, especially in immunocompromised patients. PMID:27419178

  8. A ten year, multicentre study of coagulase negative staphylococcal infections in Australasian neonatal units

    PubMed Central

    Isaacs, D

    2003-01-01

    Objective: To study late onset systemic infections with coagulase negative staphylococci. Methods: Prospective longitudinal study of coagulase negative staphylococcal infection in 18 Australasian neonatal nurseries. Results: From 1991 to 2000 inclusive, there were 1281 cases of coagulase negative staphylococcal (CoNS) sepsis, comprising 57.1% of all late onset infections. The male/female ratio was 1.27:1 (p < 0.05). The incidence of CoNS sepsis was 3.46 episodes per 1000 live births. Most infected babies (71%) were 24–29 weeks gestation at birth (mode 26 weeks). The first positive culture was day 7–14 in 49% of babies (mode 10 days). Five cases of meningitis were reported, an incidence of 0.4% of all CoNS infections. Twenty nine babies (2.3%) had concurrent necrotising enterocolitis and CoNS septicaemia. Four babies (0.3%) died from CoNS infection, but CoNS infection possibly contributed to the death of an additional 20 babies (1.6%). The mortality directly attributable to CoNS infection was significantly lower than that from late onset infections with Staphylococcus aureus (13.1%; relative risk (RR) = 36.1 (95% confidence interval (CI) 13.0 to 100.2) or with Gram negative bacilli (14.2%; RR = 45.5 (95% CI 16.8 to 123.3)). Conclusions: CoNS are currently responsible for most late onset neonatal infections. Most infected babies are < 30 weeks gestation at birth, and usually present between 7 and 14 days of age. CoNS infections may be associated with necrotising enterocolitis, although causality is unproven. Neonatal CoNS infections are relatively benign: meningitis is rare and mortality low compared with infection from other organisms. Over-vigorous attempts to reduce the incidence of CoNS infections using prophylactic antibiotics are not advisable. PMID:12598493

  9. Incidence of primary breast cancer in Iran: Ten-year national cancer registry data report.

    PubMed

    Jazayeri, Seyed Behzad; Saadat, Soheil; Ramezani, Rashid; Kaviani, Ahmad

    2015-08-01

    Breast cancer is the leading type of malignancy and the leading cause of cancer-related deaths in women worldwide. The screening programs and advances in the treatment of patients with breast cancer have led to an increase in overall survival. Cancer registry systems play an important role in providing basic data for research and the monitoring of the cancer status. In this study, the results of the 10-year national cancer registry (NCR) of Iran in breast cancer are reviewed. NCR database records were searched for primary breast cancer records according to ICD-O-3 coding and the cases were reviewed. A total of 52,068 cases were found with the coding of primary breast cancer. Females constituted 97.1% of the cases. Breast cancer was the leading type of cancer in Iranian females, accounting for 24.6% of all cancers. The mean age of the women with breast cancer was 49.6 years (95%CI 49.5-49.6). Most of the cases (95.7%) were registered as having invasive pathologies (behavior code 3). The most common morphology of primary breast cancer was invasive ductal carcinoma (ICD-O 8500/3) followed by invasive lobular carcinoma (ICD-O 8520/3) with relative frequencies of 77.8% and 5.2%, respectively. The average annual crude incidence of primary breast cancer in females was 22.6 (95%CI 22.1-23.1) per 100,000 females, with an age-standardized rate (ASR) of 27.4 (95%CI 22.5-35.9). There were no data on survival, staging or immunohistochemical marker(s) of the breast-cancer-registered cases. The incidence of breast cancer in Iran is lower than in low-middle-income neighboring countries. The NCR data registry of breast cancer is not accurate in monitoring the effect of screening programs or determining the current status of breast cancer in Iran. Screening programs of breast cancer in Iran have failed to enhance the detection of the patients with in situ lesion detection. A quality breast cancer registry and a screening program for breast cancer are both needed.

  10. Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins

    PubMed Central

    Steves, Claire J.; Mehta, Mitul M.; Jackson, Stephen H.D.; Spector, Tim D.

    2016-01-01

    Background Many observational studies have shown a protective effect of physical activity on cognitive ageing, but interventional studies have been less convincing. This may be due to short time scales of interventions, suboptimal interventional regimes or lack of lasting effect. Confounding through common genetic and developmental causes is also possible. Objectives We aimed to test whether muscle fitness (measured by leg power) could predict cognitive change in a healthy older population over a 10-year time interval, how this performed alongside other predictors of cognitive ageing, and whether this effect was confounded by factors shared by twins. In addition, we investigated whether differences in leg power were predictive of differences in brain structure and function after 12 years of follow-up in identical twin pairs. Methods A total of 324 healthy female twins (average age at baseline 55, range 43-73) performed the Cambridge Neuropsychological Test Automated Battery (CANTAB) at two time points 10 years apart. Linear regression modelling was used to assess the relationships between baseline leg power, physical activity and subsequent cognitive change, adjusting comprehensively for baseline covariates (including heart disease, diabetes, blood pressure, fasting blood glucose, lipids, diet, body habitus, smoking and alcohol habits, reading IQ, socioeconomic status and birthweight). A discordant twin approach was used to adjust for factors shared by twins. A subset of monozygotic pairs then underwent magnetic resonance imaging. The relationship between muscle fitness and brain structure and function was assessed using linear regression modelling and paired t tests. Results A striking protective relationship was found between muscle fitness (leg power) and both 10-year cognitive change [fully adjusted model standardised β-coefficient (Stdβ) = 0.174, p = 0.002] and subsequent total grey matter (Stdβ = 0.362, p = 0.005). These effects were robust in discordant

  11. Ten years' experience using an integrated workers' compensation management system to control workers' compensation costs.

    PubMed

    Bernacki, Edward J; Tsai, Shan P

    2003-05-01

    This work presents 10 years of experience using an Integrated Workers' Compensation Claims Management System that allows safety professionals, adjusters, and selected medical and nursing providers to collaborate in a process of preventing accidents and expeditiously assessing, treating, and returning individuals to productive work. The hallmarks of the program involve patient advocacy and customer service, steerage of injured employees to a small network of physicians, close follow-up, and the continuous dialogue between parties regarding claims management. The integrated claims management system was instituted in fiscal year 1992 servicing a population of approximately 21,000 individuals. The system was periodically refined and by the 2002 fiscal year, 39,000 individuals were managed under this paradigm. The frequency of lost-time and medical claims rate decreased 73% (from 22 per 1000 employees to 6) and 61% (from 155 per 1000 employees to 61), respectively, between fiscal year 1992 and fiscal year 2002. The number of temporary/total days paid per 100 insureds decreased from 163 in fiscal year 1992 to 37 in fiscal year 2002, or 77%. Total workers' compensation expenses including all medical, indemnity and administrative, decreased from $0.81 per $100 of payroll in fiscal year 1992 to $0.37 per $100 of payroll in fiscal year 2002, a 54% decrease. More specifically, medical costs per $100 of payroll decreased 44% (from $0.27 to $0.15), temporary/total, 61% (from $0.18 to $0.07), permanent/partial, 63% (from $0.19 to $0.07) and administrative costs, 48% ($0.16 to $0.09). These data suggests that workers' compensation costs can be reduced over a multi-year period by using a small network of clinically skilled health care providers who address an individual workers' psychological, as well as physical needs and where communication between all parties (e.g., medical care providers, supervisors, and injured employees) is constantly maintained. Furthermore, these results

  12. Ten-year trends in overweight and obesity in the adult Portuguese population, 1995 to 2005

    PubMed Central

    2011-01-01

    Background There is little information regarding the trends in body mass index (BMI) and obesity in the overall Portuguese population, namely if these trends are similar according to educational level. In this study, we assessed the trends in the prevalence of overweight and obesity in the Portuguese population, overall and by educational level. Methods Cross-sectional national health interview surveys conducted in 1995-6 (n = 38,504), 1998-9 (n = 38,688) and 2005-6 (n = 25,348). Data were derived from the population and housing census of 1991 and two geographically-based strata were defined. The sampling unit was the house, and all subjects living in the sampling unit were surveyed. Height and weight were self-reported; the effects of gender, age group and educational level were also assessed by self-reported structured questionnaires. Bivariate comparisons were performed using Chi-square or analysis of variance (ANOVA). Trends in BMI levels were assessed by linear regression analysis, while trends in the prevalence of obesity were assessed by logistic regression. Results Mean (±standard deviation) BMI increased from 25.2 ± 4.0 in 1995-6 to 25.7 ± 4.5 kg/m2 in 2005-6. Prevalence of overweight remained stable (36.1% in 1995-6 and 36.4% in 2005) while prevalence of obesity increased (11.5% in 1995-6 and 15.1% in 2005-6). Similar findings were observed according to age group. Mean age-adjusted BMI increase (expressed in kg/m2/year and 95% confidence interval) was 0.073 (0.062, 0.084), 0.016 (0.000, 0.031) and 0.073 (0.049, 0.098) in men with primary, secondary and university levels, respectively; the corresponding values in women were 0.085 (0.073, 0.097), 0.052 (0.035, 0.069) and 0.062 (0.038, 0.084). Relative to 1995-6, obesity rates increased by 48%, 41% and 59% in men and by 40%, 75% and 177% in women with primary, secondary and university levels, respectively. The corresponding values for overweight were 6%, 1% and 23% in men and 5%, 7% and 65% in women

  13. ESEA Ten Years Later

    ERIC Educational Resources Information Center

    Halperin, Samuel

    1975-01-01

    Achievements cited for ESEA include that it broke the log jam on federal aid to education, spotted the needs of children, fueled other movements toward equality of educational opportunity, recruited quality personnel, promoted public-nonpublic cooperation, promoted parental and community involvement, and the evaluation/accountability movement.…

  14. Ten years after Chernobyl

    SciTech Connect

    Becker, K.

    1996-12-31

    As was amply demonstrated during the EU/IAEA/WHO Summing-up-Conference in Vienna, Austria, April 8-12, 1996, the radiological consequences of the Chernobyl accident were, fortunately, not as serious as frequently presented in the media: 28 people died from acute radiation syndrome in 1986, 14 more of possibly radiation-related causes since. Of the <1000 thyroid cancers in children, 90 to 95% are curable. There have so far been no other demonstrable increases in the former Soviet Union, as well as in Western Europe, of leukemias, solid cancers, or genetic defects, nor are any to be expected in the future. Even among the {open_quotes}liquidators{close_quotes} with doses {approximately}100 mSv, of the {approximately}150 additional expected leukemias during the 10 yr after the accident, none have been observed. The economical, social, and political consequences, however, both in the former Soviet Union and in Western Europe, have been very substantial. Whole countries developed an hysterical `radiation sickness.` As A. Merkel, the German Minister of Environment and Reactor Safety, who chaired the conference, pointed out, `the radiation sensitivity of societies far exceeds that of individuals.` It is obvious that important groups in Ukraine, Belaurus, and Russia try to blame a large fraction of all economic, social, and health problems during the last decade, which are substantial ({approx} 6 yr less life expectancy, twice the homicides and traffic deaths, increased alcoholism, and so forth), on radiation of the Chernobyl accident in an effort to attract more support. Western scientists refute such claims but admit large non-radiation-related problems caused by the accident.

  15. Ten years of reviews.

    PubMed

    Grant, Maria J

    2017-03-01

    The March 2017 issue of the Health Information and Libraries Journal marks the 10 year anniversary of the inaugural review published in the journal's review series. The review series was conceived to meet the growing appetite of health library and information workers to access synthesised evidence to inform their practice; something we'd already been doing to support medics in their practice. This editorial looks back on the 10 years and the inspiration which saw the development of a typology of review types and associated methodologies to address the lack of consistent guidelines on the features a review should incorporate.

  16. Ten Years of Chandra

    NASA Technical Reports Server (NTRS)

    Weisskopf, Martin C.

    2009-01-01

    We celebrated the 10-th anniversary of the Launch of the Chandra X-ray Observatory on July 13, 2009. During these 10 years data from this Great Observatory have had a profound impact on 21st century astrophysics. With its unrivaled capability to produce sub-arcsecond images, the Observatory has enabled astronomers to make new discoveries in topics as diverse as comets and cosmology. We shall review some of the highlights, discuss the current status, and future plans.

  17. Ten Years Later.

    ERIC Educational Resources Information Center

    Larrick, Nancy

    The past decade has given us an encouraging number of well-written and appealing children's books which give an authentic picture of the black people in the United States in dramatic text and brilliant illustrations. Indeed, in this period, a whole new sense of realism has come into children's literature which portrays urgent social issues and…

  18. The dust E ring of Saturn as seen from the HF radio antennas on Cassini over the past ten years

    NASA Astrophysics Data System (ADS)

    Moncuquet, M.; Schippers, P.

    2014-04-01

    ). Since this technique reveals the dust concentration together with the electron density and temperature, with the same instrument, it is particularly suitable to study dustplasma interactions. In summary, we obtained, over the past ten years of Cassini's radio in situ observations, the quasiequatorial dust density E-ring profile for the typical dust size populations (between 1 and 0.1 μm), which clearly exhibits both the plasma drag effect and the erosion of the grains from the Enceladus orbit to 13 Rs. We have also identified an excess of confined dust grains between Tethys and Dione's orbits and some specific plasma-dust interaction processes inside the Enceladus' plumes, as the electron depletion occurring in the Enceladus' volcanic plumes[3], when the high dust density traps most of the plasma electrons. We plan to show and compare these new results to some previous observations, simulations or theories.

  19. Endovascular treatment of false-aneurysm ten years after dacron patch aortoplasty for coarctation of the aortic isthmus. Report of a case.

    PubMed

    Illuminati, Giulio; Pacilè, Maria Antonietta; Palumbo, Piergaspare; Salvatori, Filippo Maria; Vietri, Francesco

    2013-01-01

    False aneurysm degeneration is a known complication of patch aortoplasty for coarctation of the aortic isthmus. Open surgical treatment consists of prosthetic graft repair of the involved aorta, often requires circulatory arrest to achieve a safe proximal aortic control and perform proximal anastomosis, and finally is associated with substantial perioperative morbidity. Endografting of the diseased aorta is a valuable alternative to open repair, when feasible, with good short and long term results. We now report one more case of false aneurysm ten years after Dacron patch aortoplasty for isthmic coarctation in a 26-year-old woman, successfully treated by endovascular repair via the left common iliac artery, and a complete exclusion of the aneurysm at two year follow-up.

  20. Prostate cancer treatment and ten-year survival among group/staff HMO and fee-for-service Medicare patients.

    PubMed Central

    Potosky, A L; Merrill, R M; Riley, G F; Taplin, S H; Barlow, W; Fireman, B H; Lubitz, J D

    1999-01-01

    OBJECTIVE: To compare treatment patterns and the ten-year survival of prostate cancer patients in two large, nonprofit, group/staff HMOs to those of patients receiving care in the fee-for-service health setting. DATA SOURCES/STUDY DESIGN: A cohort of men age 65 and over diagnosed with prostate cancer between 1985 and the end of 1992 and followed through 1994. Subjects (n = 21,741) were ascertained by two population-based tumor registries covering the greater San Francisco-Oakland and Seattle-Puget Sound areas. Linkage of registry data with Medicare claims data and with HMO inpatient utilization data allowed the determination of health plan enrollment and the measurement of comorbid conditions. Multivariate regression models were used to examine HMO versus FFS treatment and survival differences adjusting for sociodemographic and clinical characteristics. PRINCIPAL FINDINGS: Among cases with non-metastatic prostate cancer, HMO patients were more likely than FFS patients to receive aggressive therapy (either prostatectomy or radiation) in San Francisco-Oakland (odds ratio [OR] = 1.69, 95% CI = 1.46-1.96) but not in Seattle (OR = 1.15, 0.93-1.43). Among men receiving aggressive therapy, HMO cases were three to five times more likely to receive radiation therapy than prostatectomy. Overall mortality was equivalent over ten years (HMO versus FFS mortality risk ratio [RR] = 1.01, 0.94-1.08), but prostate cancer mortality was higher for HMO cases than for FFS cases (RR = 1.25, 1.13-1.39). CONCLUSION: Despite marked treatment differences for clinically localized prostate cancer, overall ten-year survival for patients enrolled in two nonprofit group/staff HMOs was equivalent to survival among patients receiving care in the FFS setting, even after adjustment for sociodemographic and clinical characteristics. Similar overall but better prostate cancer-specific survival among FFS patients is most plausibly explained by differences between the HMO and FFS patients in both tumor

  1. Ten years after the IOM report: Engaging residents in quality and patient safety by creating a House Staff Quality Council.

    PubMed

    Fleischut, Peter M; Evans, Adam S; Nugent, William C; Faggiani, Susan L; Lazar, Eliot J; Liebowitz, Richard S; Forese, Laura L; Kerr, Gregory E

    2011-01-01

    Ten years after the 1999 Institute of Medicine report, it is clear that despite significant progress, much remains to be done to improve quality and patient safety (QPS). Recognizing the critical role of postgraduate trainees, an innovative approach was developed at New York-Presbyterian Hospital, Weill Cornell Medical Center to engage residents in QPS by creating a Housestaff Quality Council (HQC). HQC leaders and representatives from each clinical department communicate and partner regularly with hospital administration and other key departments to address interdisciplinary quality improvement (QI). In support of the mission to improve patient care and safety, QI initiatives included attaining greater than 90% compliance with medication reconciliation and reduction in the use of paper laboratory orders by more than 70%. A patient safety awareness campaign is expected to evolve into a transparent environment where house staff can openly discuss patient safety issues to improve the quality of care.

  2. Ten years of a model of aesthetic appreciation and aesthetic judgments : The aesthetic episode - Developments and challenges in empirical aesthetics.

    PubMed

    Leder, Helmut; Nadal, Marcos

    2014-11-01

    About a decade ago, psychology of the arts started to gain momentum owing to a number of drives: technological progress improved the conditions under which art could be studied in the laboratory, neuroscience discovered the arts as an area of interest, and new theories offered a more comprehensive look at aesthetic experiences. Ten years ago, Leder, Belke, Oeberst, and Augustin (2004) proposed a descriptive information-processing model of the components that integrate an aesthetic episode. This theory offered explanations for modern art's large number of individualized styles, innovativeness, and for the diverse aesthetic experiences it can stimulate. In addition, it described how information is processed over the time course of an aesthetic episode, within and over perceptual, cognitive and emotional components. Here, we review the current state of the model, and its relation to the major topics in empirical aesthetics today, including the nature of aesthetic emotions, the role of context, and the neural and evolutionary foundations of art and aesthetics.

  3. Ten-year trends in HIV prevalence among visitors to public health centers under the National HIV Surveillance System in Korea, 2000 to 2009

    PubMed Central

    2012-01-01

    Background Korea saw a sharp increase in HIV diagnosis from 2000. This serious public health concern must be monitored diligently. We identified the characteristics and trends in HIV prevalence among visitors to public health centers (PHCs) from 2000 to 2009. Methods We retrieved ten-year data of HIV tests from 253 PHCs. The HIV prevalence was analyzed by gender, age, nationality, region, and reason for HIV testing. Data were analyzed using logistic regression and score test for trend. Results HIV prevalence among PHCs’ visitors has rapidly increased for six years since 2000, decreased from 2006, and then remained stable. Approximately 50% of total HIV tests were performed for sexually transmitted infection risk group (STI RG), who were tested 1.4 times within a year. Women and the 20s comprised approximately 70% and 40% of PHCs’ visitors, respectively. The prevalence of voluntary test takers was the highest and showed most rapid increase (P = 0.007), but that of prisoners declined (P = 0.003). The prevalence of STI RG was lower than those of the other groups and remained stable throughout the ten-year period (P = 0.606). Percentage of anonymous tests was 2–3% of a total HIV tests, but overall HIV-positive rate showed a rapid increase (P < 0.001). Conclusions As voluntary or anonymous testing groups are actively engaged in learning their status of HIV, these groups showed the highest in HIV infection. Groups in the population with these characteristics should be located and encouraged to be tested, and offered anonymity. This study suggests that it is important to ascertain the characteristics of people choosing to take voluntary testing. PMID:23020818

  4. [A regional alliance in nutritional management-ten years of collaboration with an nutrition support team network].

    PubMed

    Ibata, Takeshi; Hidaka, Kumi; Shinoki, Keiji; Matsuoka, Mio; Hata, Akiko; Nakashita, Chisako; Mito, Saori; Doi, Seiko; Komuro, Ryutaro; Iijima, Shohei

    2012-12-01

    Ten years has passed since we began the nutrition support team(NST)to make a regional alliance between local institutions for construction of the NST network. The network was formed with the following aims: 1) regional joint conferences for learning about nutrition with family doctors, facilities, and hospitals; 2) open general meetings for information about nutrition within the suburbs of our city; 3) preparing and sending an NST manual about parenteral nutrition(PN)and enteral nutrition(EN); and 4) preparation of an NST summary of patient malnutrition to foster mutual understanding. We produced a questionnaire summarizing the completion of nutritional management in patients. The following positive benefits were observed: 1) improved nutritional motivation and technique; 2) reduced nutritional confusion after discharge from our hospital; and 3) lower levels of anxiety in the facilities, the patient, and among the patient's family. In addition, follow-upinquiries allowed us to estimate whether our nutritional strategy was adequate. A more widely open regional alliance is needed in the future to strengthen patient nutrition following hospital discharge.

  5. Resistance of herpes simplex viruses to acyclovir: an update from a ten-year survey in France.

    PubMed

    Frobert, Emilie; Burrel, Sonia; Ducastelle-Lepretre, Sophie; Billaud, Geneviève; Ader, Florence; Casalegno, Jean-Sébastien; Nave, Viviane; Boutolleau, David; Michallet, Mauricette; Lina, Bruno; Morfin, Florence

    2014-11-01

    The widespread use of acyclovir (ACV) and the increasing number of immunocompromised patients have raised concern about an increase in ACV-resistant herpes simplex virus (HSV). ACV resistance has traditionally been a major concern for immunocompromised patients with a frequency reported between 2.5% and 10%. The aim of this study was to reassess the status of HSV resistance to ACV in immunocompetent and immunocompromised patients over a ten year period, between 2002 and 2011. This was done by retrospectively following 1425 patients. In immunocompetent patients, prevalence of resistance did not exceed 0.5% during the study period; whereas in immunocompromised patients, a significant increase was observed, rising from 3.8% between 2002 and 2006 (7/182 patients) to 15.7% between 2007 and 2011 (28/178) (p=0.0001). This sharp rise in resistance may largely be represented by allogeneic hematopoietic stem cell transplant patients, in which the prevalence of ACV resistance rose similarly from 14.3% (4/28) between 2002 and 2006 to 46.5% (26/56) between 2007 and 2011 (p=0.005). No increase in ACV resistance was detected in association with other types of immune deficiencies. Genotypic characterization of HSV UL23 thymidine kinase and UL30 DNA polymerase genes revealed 11 and 7 previously unreported substitutions, respectively. These substitutions may be related to potential polymorphisms, drug resistance, or other mutations of unclear significance.

  6. [1984-1994: Ten years of skin flaps. Development of transfer techniques. New methods of autoplasty described during this period].

    PubMed

    Martin, D

    1995-10-01

    Ten years of flaps represent a little and a lot. It is little compared to the 2600 years since the first flap in plastic surgery: the Susruta Indian flap, but it is a lot in view of the phenomenal acceleration of this speciality since the Second World War. In 1994 alone, more than two hundred references are listed under the heading "new flaps". As it is impossible to be exhaustive, the author has chosen to focus on two main aspects: a theoretical review of new transfer techniques, dealing successively with: the principles of reverse flow flaps, venous flaps, neurocutaneous flaps, so-called "extracorporeal" transfers, reverse flow YV technique; and practical aspects based on a review of eighteen autoplasties or donor sites selected for their surgical value, their reproductibility and their innovative nature. The author's objective is not to present a technical treatise, but rather to make the reader aware of several key points or even, in some cases, the very existence of these autoplasties. This paper is designed to be didactic, with extensive references, in order to act as a practical guide. It also demonstrates, as if there were any need, to what extent plastic surgery is able to create new solutions and the essential value of continuing research.

  7. Ten-year growth response of young Douglas-fir to variable density varnishleaf ceanothus and herb competition

    USGS Publications Warehouse

    Monleon, V.J.; Newton, M.; Hooper, C.; Tappeiner, J. C.

    1999-01-01

    The effect of different densities of varnishleaf ceanothus (Ceanothus velutinus var. laevigatus) and herbaceous vegetation control on stem diameter, height, and volume of plantation Douglas-fir (Pseudotsuga menziesii var. menziesii) seedlings was examined during the 10 yr following planting. Initial densities of ceanothus ranged between 0 and 15,000 seedlings/ha and were obtained by interplanting ceanothus germinants or chemical thinning after clearcutting and broadcast-burning. Herbaceous vegetation control was achieved by a single application of glyphosate following planting, with shrub seedlings covered. Ceanothus density in the range of 0 to 6,750 plants/ha did not have an effect on Douglas-fir diameter, height, or volume at age 10; however, Douglas-fir growth was significantly decreased when ceanothus densities reached 15,000 plants/ha. Ten years after planting, Douglas-fir volume in the treatments with 6,750 ceanothus/ha or less was 1.7 times greater than that in the 15,000 ceanothus/ha treatment. On the other hand, removal of herbaceous vegetation after planting significantly increased tree diameter, height, and volume, regardless of ceanothus density. Even 10 yr after the application of the treatment, trees without early herb competition grew faster and had mean dbh, height, and volume that were 1.02 cm, 0.55 m, and 12.98 dm3/tree greater respectively than those with herbs. Thus, a treatment at plantation establishment to control herbaceous vegetation and to reduce ceanothus density to less than 7,000 plants/ha will ensure an increase in growth and stocking for at least 10 yr.

  8. Quality of Life in the Late Follow-Up of Ulcerative Colitis Patients Submitted to Restorative Proctocolectomy with Sphincter Preservation Over Ten Years Ago

    PubMed Central

    Meyer, Alberto Luiz Monteiro; Teixeira, Magaly Gêmeo; de Almeida, Maristela Gomes; Kiss, Desidério Roberto; Nahas, Sergio Carlos; Cecconello, Ivan

    2009-01-01

    OBJECTIVE To evaluate, by means of the Inflammatory Bowel Disease Questionnaire (IBDQ), the quality of life of ulcerative colitis patients submitted to proctocolectomy with sphincter preservation using J-pouch reconstruction over ten years ago. METHODS The study consisted of 36 patients interviewed using the Inflammatory Bowel Disease Questionnaire. The score scale, resulting from the addition of each answer, ranged from 32 to 224, where the highest score indicates the best quality of life. The chi square test was used to verify the existence of meaningful differences between the results of the questionnaire and age, and gender proportion. For each section, as well as for all of them combined, the Kruskal-Wallis test was used to verify if there were differences in the Inflammatory Bowel Disease Questionnaire scores among the groups in relation to the proportions. RESULTS After applying the Inflammatory Bowel Disease Questionnaire, it was determined that quality of life was considered excellent for 9 (25%), good for 11 (30.6%), regular for 13 (36.1%), and bad for 3 (8.3%) patients. In our study, we determined that 85% of the patients were pleased with and thankful for the surgery that they underwent. CONCLUSION We can conclude that the possibility of sphincter preservation should always be taken into account, since patients remain clinically stable and have a high quality of life even after long periods. PMID:19759881

  9. What do you want to be in ten years? - Advising meteorology students in the post-Twister era

    NASA Astrophysics Data System (ADS)

    Snow, J. T.; Hempe, M.

    2012-12-01

    "What do you want to be in ten years?' This is a question we ask our students, freshmen and transfer, when they first arrive in the College student services center. Often the answer is "I don't know. I just want to be in meteorology." This response leads to a discussion of career opportunities in meteorology and related fields, including what might be called faux-careers, such as professional storm chasing and weather tour operations. (Students often have been misled by what they have seen in television shows.) Many students arrive on our doorstep with their heart set on a degree in meteorology, but lack knowledge of what the field is about or how challenging a meteorology degree program really is. We find ourselves spending a great deal of time convincing students that they need to explore the real opportunities in meteorology and related fields, which are many. Fortunately, because of the concentration of University and federal weather organizations in the National Weather Center and private sector weather companies in adjacent buildings, we are able to show concrete examples of real careers by means of tours, job shadowing, and introductions to alumni employed in these organizations. Also, as the students' progress in their studies, they discover the many opportunities for undergraduate employment, research experiences, and internships in these same organizations, through which they gain an appreciation for what constitutes a real career in modern meteorology. Further, many of today's careers in meteorology require a broad, global perspective. Unfortunately, many meteorology students have not traveled widely, but again have only seen what the media provides about distant lands and peoples. Accordingly, we encourage our undergraduate students to take advantage of our unique opportunities for overseas experiences in meteorology. Through arrangements with the met programs at the University of Reading (England), Monash University (Australia), and University of

  10. A new SO2 emissions budget for Anatahan volcano (Mariana Islands) based on ten years of satellite observations

    NASA Astrophysics Data System (ADS)

    McCormick, Brendan; Popp, Christoph; Andrews, Benjamin; Cottrell, Elizabeth

    2015-04-01

    Satellite remote sensing offers great potential for the study of sulphur dioxide (SO2) gas emissions from volcanoes worldwide. Anatahan is a remote volcano in the Mariana Islands, SW Pacific. Existing SO2 emissions data from Anatahan, from ground-based UV spectrometer measurements, place the volcano among the largest natural SO2 sources worldwide. However, these measurements are limited in number and only available from intervals of eruptive activity. Activity varies widely at Anatahan: over the past decade, records held in the Smithsonian Institution Global Volcanism Program Volcanoes of the World database describe the alternation of intense eruptions with long intervals of quiescence, where much lower intensity activity took place. We present ten years of satellite-based measurements of SO2 in the atmosphere over Anatahan, using data from the UV spectrometers OMI, GOME-2, and SCIAMACHY, and the IR spectrometer AIRS. We find Anatahan's emissions to be highly variable both within and between intervals of eruption and quiescence. We demonstrate a close agreement between trends in SO2 emission evident from our remote sensing data and records of activity compiled from a range of other sources and instruments, across daily to annual temporal scales. Mean eruptive SO2 emissions at Anatahan are ~6400 t/d, and range from <1000 to >18000 t/d. Quiescent emissions are below our instrument detection limits and are therefore unlikely to exceed 150-300 t/d. Overall, accounting for both eruptive and quiescent emissions, we calculate a revised decadal mean SO2 emission rate of 1060-1200 t/d. We further calculate a total decadal SO2 yield from Anatahan of 4-5 Mt, significantly lower than the 17-34 Mt calculated if ground-based campaign data are used in isolation. The use of isolated measurements to extrapolate longer term emissions budgets is subject to clear uncertainty, and we argue that our satellite observations, covering a longer interval of Anatahan's history, are better

  11. Let Book Joy Begin @ Your Library[R]!: Ten Years of El Dia de los Ninos/El Dia de los Libros

    ERIC Educational Resources Information Center

    Roy, Loriene

    2007-01-01

    Ten years ago, in 1996, poet and children's book author, Pat Mora began celebrating "book joy" by founding a children's book and reading day, El Dia de los Ninos/El Dia de los Libros or Children's Day/Book Day. Dia is modeled on National Children's Day Celebrations in Mexico held since 1925 when it was launched in conjunction with a…

  12. OYSTER POPULATUION ESTIMATION IN SUPPORT OF THE TEN-YEAR GOAL FOR OYSTER RESOTRATION IN THE CHESAPEAKE BAY: DEVELOPING STRATEGIES FOR RESTORING AND MANAGING THE EASTERN OYSTER

    EPA Science Inventory

    Mann, Roger, Steve Jordan, Gary Smith, Kennedy Paynter, James Wesson, Mary Christman, Jessica Vanisko, Juliana Harding, Kelly Greenhawk and Melissa Southworth. 2003. Oyster Population Estimation in Support of the Ten-Year Goal for Oyster Restoration in the Chesapeake Bay: Develop...

  13. BIFoR FACE: A ten-year Free-Air Carbon Dioxide Enrichment (FACE) Experiment in Old Growth Deciduous English Woodland

    NASA Astrophysics Data System (ADS)

    Thomas, R. M.; MacKenzie, A. R.; Ellsworth, D.; Hemming, D.; Crous, K.; Pope, F.; Blaen, P.; Poynter, A.; Hamilton, L.; Blenkhorn, D.; Jarvis-Rouse, F.

    2015-12-01

    The Birmingham Institute of Forest research (BIFoR) will perform fundamental physical, biological, ecological, social and cultural research of direct relevance to forested landscapes worldwide. A core platform for BIFoR to study the ten-year response of a mature temperate deciduous forest ecosystem to against a large step-change in atmospheric [CO2] is the BIFoR Free-Air Carbon Dioxide Enrichment (FACE) experiment. BIFoR FACE is being established in Mill Haft, a mature (~150 year-old) oak (Quercus robur) and hazel (Corylus avellana) coppice-with-standards woodland in central England. The facility will enable elevated CO2 (eCO2) treatments to be introduced in 30 m diameter rings (3 treatment and 6 control plots), commencing in spring 2016. Under eCO2 conditions primary research questions will investigate carbon uptake and storage, corresponding nutrient limitations, and biodiversity and ecosystem responses. As well as describing the facility and experimental design, we present baseline data collected throughout 2015, prior to fumigation. These data include: biophysical tree properties; atmospheric CO2/H2O fluxes; airborne and ground laser scatterometry; leaf area index; geophysical survey data; phenology camera derivatives; soil and water chemical and physical properties; and invertebrate surveys. Data from an intensive campaign conducted during august 2015 are also shown, including in- and above- canopy characterisation of biogenic VOCs using a Proton Transfer Reaction Mass Spectrometer, aerosol loading including bioaerosols, and enhanced atmospheric chemistry. Further campaign results are presented from leaf level photosynthetic carbon-dioxide response curve (A/Ci) performed at different canopy heights on oak trees, and on the dominant understory species - hazel and sycamore (Acer pseudoplatinus) across the site. BIFoR FACE is an exciting new international facility for forest science - ideas for collaborations are encouraged. Please see http

  14. The First Epidemic and New-emerging Human Fascioliasis in Kermanshah (Western Iran) and a Ten-year Follow Up, 1998-2008

    PubMed Central

    Hatami, Hossein; Asmar, Mahdi; Masoud, Jafar; Mansouri, Feizollah; Namdaritabar, Hengameh; Ramazankhani, Ali

    2012-01-01

    Background: Fascioliasis is one of the most common zoonotic diseases in Iran and other parts of the world. Although the largest epidemic of this disease has occurred in northern provinces of Iran (Guilan) during the past two decades and a few cases have also been reported in Tehran and the other provinces, there has been no evidence of its’ occurrence in western provinces of Iran such as Kermanshah before the outbreak which is being reported. Methods: The study was conducted by teamwork of infectious disease specialist, parasitologist, general practitioner, entomologist, and laboratory technician. It is an “epidemic investigation” and a cross sectional descriptive one. Clinical data and para-clinical changes are recorded considering all of the population of a village in Kangavar, one of the suburbs of Kermanshah (western Iran). Results: The mean age was 21.65, (SD=12.44). Fifty three percent were female, and all of them were farmers. Eighty two percent had a history of watercress ingestion in a period of 1-2 months before the admission and 18% consumed other vegetables. The average of eosinophils was 32.35% (SD=26). The patients’ Enzyme Linked Immunosorbent Assay (ELISA) and Counter Current Immuno-electrophoresis (CCIE) serological tests were reported positive by the department of parasitology, Pasteur Institute of Iran. Treatment response to triclabendazole was excellent. A ten-year clinical and laboratory follow-up revealed no evidence of abnormality in treated patients. Conclusions: It was the first case of human fascioliasis in west Iran and was a real epidemic and an emerging infectious disease for this area at that time. The clinical symptoms were less severe compared with other reports. Health education to inhabitants and health care workers can lead to rapid detection of such outbreaks. PMID:22624083

  15. Secular trends: a ten-year comparison of the amount and type of physical activity and inactivity of random samples of adolescents in the Czech Republic

    PubMed Central

    2011-01-01

    Background An optimal level of physical activity (PA) in adolescence influences the level of PA in adulthood. Although PA declines with age have been demonstrated repeatedly, few studies have been carried out on secular trends. The present study assessed levels, types and secular trends of PA and sedentary behaviour of a sample of adolescents in the Czech Republic. Methods The study comprised two cross-sectional cohorts of adolescents ten years apart. The analysis compared data collected through a week-long monitoring of adolescents' PA in 1998-2000 and 2008-2010. Adolescents wore either Yamax SW-701 or Omron HJ-105 pedometer continuously for 7 days (at least 10 hours per day) excluding sleeping, hygiene and bathing. They also recorded their number of steps per day, the type and duration of PA and sedentary behaviour (in minutes) on record sheets. In total, 902 adolescents (410 boys; 492 girls) aged 14-18 were eligible for analysis. Results Overweight and obesity in Czech adolescents participating in this study increased from 5.5% (older cohort, 1998-2000) to 10.4% (younger cohort, 2008-2010). There were no inter-cohort significant changes in the total amount of sedentary behaviour in boys. However in girls, on weekdays, there was a significant increase in the total duration of sedentary behaviour of the younger cohort (2008-2010) compared with the older one (1998-2000). Studying and screen time (television and computer) were among the main sedentary behaviours in Czech adolescents. The types of sedentary behaviour also changed: watching TV (1998-2000) was replaced by time spent on computers (2008-2010). The Czech health-related criterion (achieving 11,000 steps per day) decreased only in boys from 68% (1998-2000) to 55% (2008-2010). Across both genders, 55%-75% of Czech adolescents met the health-related criterion of recommended steps per day, however less participants in the younger cohort (2008-2010) met this criterion than in the older cohort (1998-2000) ten

  16. Ten-Year Analysis of Transfusion in Operation Iraqi Freedom and Operation Enduring Freedom: Increased Plasma and Platelet Use Correlates with Improved Survival

    DTIC Science & Technology

    2012-01-01

    evaluation of the impact of apheresis platelets used in the setting of massively transfused trauma patients. J Trauma. 2009;66(suppl 4):S77 S84...Ten-year analysis of transfusion in Operation Iraqi Freedom and Operation Enduring Freedom: Increased plasma and platelet use correlates with...coagulopathy, evaluates the effect of increased plasma and platelet (PLT) to red blood cell ratios, and analyzes other recent changes in practice

  17. A ten year summary of concurrent ambient water column and sediment toxicity tests in the Chesapeake Bay watershed: 1990-1999.

    PubMed

    Hall, Lenwood W; Anderson, Ronald D; Alden, Raymond W

    2002-06-01

    The goal of this study was to identify the relative toxicity of ambient areas in the Chesapeake Bay watershed by using a suite of concurrent water column and sediment toxicity tests at seventy-five ambient stations in 20 Chesapeake Bay rivers from 1990 through 1999. Spatial and temporal variability was examined at selected locations throughout the 10 yr study. Inorganic and organic contaminants were evaluated in ambient water and sediment concurrently with water column and sediment tests to assess possible causes of toxicity although absolute causality can not be established. Multivariate statistical analysis was used to develop a multiple endpoint toxicity index (TOX-INDEX) at each station for both water column and sediment toxicity data. Water column tests from the 10 yr testing period showed that 49% of the time, some degree of toxicity was reported. The most toxic sites based on water column results were located in urbanized areas such as the Anacostia River, Elizabeth River and the Middle River. Water quality criteria for copper, lead, mercury, nickel and zinc were exceeded at one or more of these sites. Water column toxicity was also reported in localized areas of the South and Chester Rivers. Both spatial and temporal variability was reported from the suite of water column toxicity tests. Some degree of sediment toxicity was reported from 62% of the tests conducted during the ten year period. The Elizabeth River and Baltimore Harbor stations were reported as the most toxic areas based on sediment results. Sediment toxicity guidelines were exceeded for one or more of the following metals at these two locations: arsenic, cadmium, chromium, copper, lead, nickel and zinc. At the Elizabeth River stations nine of sixteen semi-volatile organics and two of seven pesticides measured exceeded the ER-M values in 1990. Ambient sediment toxicity tests in the Elizabeth River in 1996 showed reduced toxicity. Various semi-volatile organics exceeded the ER-M values at a

  18. Ten years in the dump: An updated review of the Miocene primate-bearing localities from Abocador de Can Mata (NE Iberian Peninsula).

    PubMed

    Alba, David M; Casanovas-Vilar, Isaac; Garcés, Miguel; Robles, Josep M

    2017-01-01

    More than ten years of paleontological fieldwork during the enlargement of the Can Mata Landfill (Abocador de Can Mata [ACM]), in els Hostalets de Pierola (Vallès-Penedès Basin, NE Iberian Peninsula) led to the recovery of >60,000 Miocene vertebrate remains. The huge sampling effort (due to continuous surveillance of heavy machinery digging activity, coupled with manual excavation and screen-washing of sediments) enabled generally rare faunal elements such as pliopithecoid and hominoid primates to be found. Thanks to detailed litho-, bio- and magnetostratigraphic controls, accurate dating is possible for all the recovered primate remains from 19 of the 235 localities defined along the 234 m-thick composite stratigraphic sequence of the ACM. Here we report updated estimated (interpolated) ages for these paleontological localities and review the timing of the primate succession in this area. Our results indicate that the whole ACM sequence is late Aragonian in age (MN6 and MN7+8) and includes seven magnetozones that are correlated to subchrons C5Ar.1r to C5r.2r (ca. 12.6 to 11.4 Ma). Great apes (dryopithecines) are first recorded at 12.4-12.3 Ma, but most of the finds (Anoiapithecus, Pierolapithecus and Dryopithecus) cluster between 12.0 and 11.9 Ma, followed by some indeterminate dryopithecine remains between 11.7 and 11.6 Ma. Pliopithecoids first appear at 12.1 Ma, being subsequently represented by Pliopithecus between 11.9 and 11.7 Ma. The small-bodied hominoid Pliobates is the youngest ACM primate, with an estimated age of 11.6 Ma. Although these primates probably overlapped in time, their co-occurrence is recorded only twice, at 11.9 Ma (a dryopithecine with Pliopithecus) and at 11.6 Ma (a dryopithecine with Pliobates). The rare co-occurrence between great apes and small-bodied catarrhines might be attributable to sampling biases and/or to presumed diverging ecological preferences of these groups. In the future, more detailed analyses of the fauna

  19. Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000–2009)

    PubMed Central

    2013-01-01

    Background Urinary tract infection (UTI) is one of the most common infectious diseases at the community level. In order to assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the community (in Aveiro, Portugal) was evaluated throughout a ten-year period. Methods In this retrospective study, all urine samples from patients of the District of Aveiro, in ambulatory regime, collected at the Clinical Analysis Laboratory Avelab during the period 2000–2009 were analysed. Samples with more than 105 CFU/mL bacteria were considered positive and, for these samples, the bacteria were identified and the profile of antibiotic susceptibility was characterized. Results From the 155597 samples analysed, 18797 (12.1%) were positive for bacterial infection. UTI was more frequent in women (78.5%) and its incidence varied with age, affecting more the elderly patients (38.6%). Although E. coli was, as usual, the most common pathogen implicated in UTI, it were observed differences related to the other bacteria more implicated in UTI relatively to previous studies. The bacteria implicated in the UTI varied with the sex of the patient, being P. aeruginosa a more important cause of infection in men than in women. The incidence of the main bacteria changed over the study period (P. aeruginosa, Klebsiella spp and Providencia spp increased and Enterobacter spp decreased). Although E. coli was responsible for more than an half of UTI, its resistance to antibiotics was low when compared with other pathogens implicated in UTI, showing also the lowest percentage of multidrug resistant (MDR) isolates (17%). Bacteria isolated from females were less resistant than those isolated from males and this difference increased with the patient age. Conclusions The differences in sex and age must be taken into account at the moment of empirical prescription of antimicrobials. From the recommended antimicrobials by the European

  20. David M. Hume memorial lecture. In situ vein bypass in the treatment of femoropopliteal atherosclerotic disease: a ten year study.

    PubMed

    Hall, K V; Rostad, H

    1978-08-01

    The in situ vein bypass technic for femoropopliteal atherosclerotic disease is described. Several factors influence the long-term results, the most important being a history of myocardial disease, the size of the vein graft, and sufficient runoff.

  1. Reported Numbers of Patients with Rare Diseases Based on Ten-Year Longitudinal National Disability Registries in Taiwan

    ERIC Educational Resources Information Center

    Lin, Jin-Ding; Lin, Lan-Ping; Hung, Wen-Jiu

    2013-01-01

    This paper aims to describe a general demographic picture of patients with rare diseases in Taiwan and particularly focuses on the prevalence of rare diseases over time, age and gender distributions. We analyzed data mainly from the national disability registry from 2002 to 2011 in Taiwan, Republic of China. The results showed that the number of…

  2. A Ten-Year Study of Test Scores for College-Bound Students in the State of Washington.

    ERIC Educational Resources Information Center

    Noeth, Richard J.

    Test results (1968-1977) on the English and mathematics achievement subtests of the Washington Precollege Test (WPC), administered annually to the vast majority of college bound students in the state of Washington, were examined for evidence of test score decline. The following information from 300,000 students was analyzed by both sex and total…

  3. A ten year statistical follow-up of 1142 consecutive cases of cholesteatoma: the closed vs. the open technique.

    PubMed

    Brown, J S

    1982-04-01

    Cholesteatoma has long been a formidable adversary to the otologic surgeon. The surgical treatment has been basically by two methods, open and closed. It was felt that a study should be undertaken to compare the results obtained over a long period of time, utilizing these two methods. A need for this study existed as the same number of new cases of cholesteatoma was presenting each year. In reviewing the literature, it is found that new advancements have not yet been made in the prevention of the disease and the medical and surgical management has remained essentially the same. The ideal goal of successful surgery, namely an ear without disease, with normal hearing, and an intact drum and posterior canal wall, has been difficult to achieve in a high percentage of cases. To achieve this goal, two main surgical methods have evolved: the classical "open method," and the more recent "closed method." In the open method cases, the hearing results were often poor and the cavity presented a management problem. In the closed method there has been a fairly high occurrence of residual, and/or recurrent cholesteatoma which mecessitated a second procedure. These two methods were compared by reviewing a large number of histologically proved cholesteatoma cases 10 years after surgery, to determine the incidence of recurrence of cholesteatoma and the residual hearing function. The results of this study show conclusively that the hearing was better using the closed method, but the recurrence rate was considerably higher. This paper presents a practical method of approach to the management of all presenting cases of cholesteatoma.

  4. Use of loupes magnification and microsurgical technique in thyroid surgery: ten years experience in a single center

    PubMed Central

    D’ORAZI, V.; PANUNZI, A.; DI LORENZO, E.; ORTENSI, AL.; CIALINI, M.; ANICHINI, S.; ORTENSI, A.

    2016-01-01

    Aim The use of microsurgical technique and loupes magnification as a support to traditional surgery can help surgical performance and prevent complications in thyroid surgery. Patients and methods Between January 2004 and December 2014, 782 patients with thyroid diseases were operated by our team with microsurgical technique and loupes magnification 4.5x. All patients had pre and postoperative vocal cords assessment and calcemia and the collected data were analysed. Results Among the 782 patients, only six patients (0.77%) had unilateral vocal fold immobility treated with medical therapy, phoniatric and neck physiotherapy. All six patients showed complete laryngeal recovery of motility 6/8 weeks after treatment. There were not cases of permanent monolateral or bilateral vocal cord palsy. In 84 patients there were signs and symptoms of hypocalcemia. In 81 patients (10.36%) the restoring of biochemical parameters and the resolution of symptoms occurred between 2 and 6 weeks and in 3 cases (0.38%) there was permanent hypocalcemia more than six months. Conclusion The use of microsurgical technique and loupes magnification in thyroid surgery are safety and effective procedures, that require an appropriate training in reconstructive microsurgery, but may significantly reduce post-operative complications. Here, we report for the first time the largest series of thyroid surgery performed with the use of microsurgical technique and loupes magnification, analysing the postoperative morbidity. In view of our results, we suggest the routine use of 4.5X loupes and microsurgical technique in thyroid surgery. PMID:27734792

  5. Interpersonal victimization, posttraumatic stress disorder, and change in adolescent substance use prevalence over a ten-year period.

    PubMed

    McCart, Michael R; Zajac, Kristyn; Danielson, Carla Kmett; Strachan, Martha; Ruggiero, Kenneth J; Smith, Daniel W; Saunders, Benjamin E; Kilpatrick, Dean G

    2011-01-01

    Epidemiological studies have identified recent declines in specific types of adolescent substance use. The current study examined whether these declines varied among youth with and without a history of interpersonal victimization or posttraumatic stress disorder (PTSD). Data for this study come from two distinct samples of youth (12-17 years of age) participating in the 1995 National Survey of Adolescents (N = 3,906) and the 2005 National Survey of Adolescents-Replication (N = 3,423). Results revealed significant declines in adolescents' use of cigarettes and alcohol between 1995 and 2005; use of marijuana and hard drugs remained stable. Of importance, declines in nonexperimental cigarette use were significantly greater among youth without versus with a history of victimization and declines in alcohol use were significantly greater among youth without versus with a history of PTSD.

  6. Grooming ten-year-olds with gender stereotypes? A content analysis of preteen and teen girl magazines.

    PubMed

    Daniels, Elizabeth A; Layh, Marlee C; Porzelius, Linda K

    2016-12-01

    Extensive research shows a strong body focus in media aimed at teen girls and adult women; less is known about the content of media aimed at preteen girls. The present study investigated differences in the content of preteen versus teen girl magazines. Additionally, the content of independent compared to mainstream magazines was examined. Media frames, which are dominant themes present in media stories, used in content about the body were examined. Finally, the prevalence of appearance-focused versus non-appearance-focused content was assessed. Advertisements and general stories were analyzed. Results indicate that teen and mainstream magazines contained more appearance content than preteen and independent magazines. Appearance media frames were more common in teen than preteen magazines. Finally, teen and mainstream magazines contained more appearance-focused than non-appearance-focused content, whereas the opposite was true for preteen and independent magazines. Findings are discussed in terms of objectification theory and gender socialization practices.

  7. Ten years since the discovery of iPS cells: The current state of their clinical application.

    PubMed

    Aznar, J; Tudela, J

    On the 10-year anniversary of the discovery of induced pluripotent stem cells, we review the main results from their various fields of application, the obstacles encountered during experimentation and the potential applications in clinical practice. The efficacy of induced pluripotent cells in clinical experimentation can be equated to that of human embryonic stem cells; however, unlike stem cells, induced pluripotent cells do not involve the severe ethical difficulties entailed by the need to destroy human embryos to obtain them. The finding of these cells, which was in its day a true scientific milestone worthy of a Nobel Prize in Medicine, is currently enveloped by light and shadow: high hopes for regenerative medicine versus the, as of yet, poorly controlled risks of unpredictable reactions, both in the processes of dedifferentiation and subsequent differentiation to the cell strains employed for therapeutic or experimentation goals.

  8. Breast self-examination programmes in the trial of early detection of breast cancer: ten year findings.

    PubMed Central

    Ellman, R.; Moss, S. M.; Coleman, D.; Chamberlain, J.

    1993-01-01

    Programmes of education in breast self-examination with specialist clinics for self-referral were introduced in two health districts around 1980. Combining the results from the two centres showed no reduction in mortality from breast cancer over the following 10 years but the mortality was low in one of the centres whilst in the other it was higher than in four geographically separate comparison centres in which there was similar careful monitoring of breast cancer incidence and mortality. Because this was not a randomised controlled trial and lacked a uniform treatment protocol, biases may be responsible for the differences observed, but it is also possible that BSE education with annual reinforcement contributed to the breast cancer mortality reduction seen in one district. The overall conclusion however is that the value of breast self-examination remains unproven. PMID:8318415

  9. Use of low-level laser therapy (LLLT) in the treatment of some pulmonary diseases: ten-year experience

    NASA Astrophysics Data System (ADS)

    Derbenev, V. A.; Mikhailov, V. A.; Denisov, I. N.

    2000-06-01

    The purpose of this study was to compare the efficacy of the treatment of some pulmonary diseases with our without LLLT. 130 patients received LLLT and drug therapy, and 30 patients received only drug therapy. The obtained results on the use of LLLT show that the period of convalescence in patients with both pneumonia and exacerbation of chronic bronchitis was lower with 4-6 days compared with control group. 68 percent patients with chronic bronchitis have staunch remission more than three months. Patients with bronchial asthma reported the decreasing of both number of bronchospasms and doses of bronchodilators and glucocorticoids after LLLT. They have no exacerbation of asthma during 3-6 months; then these patients need the repetition of LLLT. In conclusion, LLLT is the suitable and effective complement to the treatment of pulmonary diseases.

  10. Ten-year experience of esophageal endoscopic submucosal dissection of superficial esophageal neoplasms in a single center

    PubMed Central

    Park, Hyung Chul; Kim, Do Hoon; Gong, Eun Jeong; Na, Hee Kyong; Ahn, Ji Yong; Lee, Jeong Hoon; Jung, Kee Wook; Choi, Kee Don; Song, Ho June; Lee, Gin Hyug; Jung, Hwoon-Yong; Kim, Jin-Ho

    2016-01-01

    Background/Aims Endoscopic submucosal dissection (ESD) of a superficial esophageal neoplasm (SEN) is a technically difficult procedure. We investigated the clinical outcomes of ESD to determine its feasibility and effectiveness for the treatment of SEN. Methods Patients who underwent ESD for SEN between August 2005 and June 2014 were eligible for this study. The clinical features of patients and tumors, histopathologic characteristics, adverse events, results of endoscopic resection, and survival were investigated. Results ESD was performed in 225 patients with 261 lesions, including 70 cases (26.8%) of dysplasias and 191 cases (73.2%) of squamous cell carcinomas. The median age was 65 years (range, 44 to 86), and the male to female ratio was 21.5:1. Median tumor size was 37 mm (range, 5 to 85) and median procedure time was 45 minutes (range, 9 to 160). En bloc resection was performed in 245 of 261 lesions (93.9%), with complete resection in 234 lesions (89.7%) and curative resection in 201 lesions (77.0%). Adverse events occurred in 33 cases (12.6%), including bleeding (1.5%), perforation (4.6%), and stricture (6.5%). During a median follow-up period of 35.0 months (interquartile range, 18 to 62), none of the patients showed local recurrence. The 5-year overall and disease-specific survival rates were 89.7% and 100%, respectively. Conclusions ESD is a feasible and effective procedure for the treatment of SEN based on our 10-year experience, which showed favorable outcomes. PMID:27618866

  11. Ten-year ground exposure of composite materials used on the Bell Model 206L helicopter flight service program

    NASA Technical Reports Server (NTRS)

    Baker, Donald J.

    1994-01-01

    Residual strength results are presented for four composite material systems that have been exposed for up to 10 years to the environment at five different locations on the North American continent. The exposure locations are near where the Bell Model 206L helicopters, which participated in a flight service program sponsored by NASA Langley Research Center and the U.S. Army, were flying in daily commercial service. The composite material systems are (1) Kevlar-49 fabric/F-185 epoxy; (2) Kevlar-49 fabric/LRF-277 epoxy; (3) Kevlar-49 fabric/CE-306 epoxy; and (4) T-300 graphite/E-788 epoxy. Six replicates of each material were removed and tested after 1, 3, 5, 7, and 10 years of exposure. The average baseline strength was determined from testing six as-fabricated specimens. More than 1700 specimens have been tested. All specimens that were tested to determine their strength were painted with a polyurethane paint. Each set of specimens also included an unpainted panel for observing the weathering effects on the composite materials. A statistically based procedure has been used to determine the strength value above which at least 90 percent of the population is expected to fall with a 95-percent confidence level. The computed compression strengths are 80 to 90 percent of the baseline (no-exposure) strengths. The resulting compression strengths are approximately 8 percent below the population mean strengths. The computed short-beam-shear strengths are 83 to 92 percent of the baseline (no-exposure) strengths. The computed tension strength of all materials is 93 to 97 percent of the baseline (no-exposure) strengths.

  12. [Evaluation of France's contributions to the Global Fund to Fight AIDS, Tuberculosis and Malaria: Ten years later].

    PubMed

    Kerouedan, D

    2014-01-01

    For 30 years, France has been very committed politically in the international combat against AIDS. The discovery of the AIDS virus at the Pasteur Institute in 1983, the AIDS summit meeting convened by Simone Veil in 1994, the excellence of research by French institutions on its virologic and other aspects as well as the socioeconomic and anthropological issues, and the strong commitment to international technical cooperation against this disease - all these have made (and continue to make) France a major political, technical, and financial participant in this battle against the combined pandemic of AIDS and tuberculosis. More than 10 years after the creation of the Global Fund, 5 years after the first evaluation of this Fund, and 2 years before the schedule for meeting the Millennium Development Goals, an assessment commissioned in 2013 from a French consulting firm of the French contributions is timely. The study was expected. Its results are disappointing. Why? Because the team chosen to conduct the assessment has a limited knowledge of the history of the interventions already funded by France and of the results of earlier assessments. The point was not to repeat the same observations but to move forward to see where they lead. In addition, the current and coming challenges are not considered. The countries to which France is providing cooperation are on the continent that after 30 years remains the most heavily affected by the pandemic. Several transitions are occurring there simultaneously: epidemiologic, demographic and urban. These metamorphoses influencing social values quite substantially, as well as risk factors for transmission of the AIDS virus; at the same time, they facilitate overcrowding and the propagation of tuberculosis. Nor do the authors consider the resistance of these infectious agents to the most commonly used drugs. The effects of the propagation of AIDS, of the expansion of armed conflicts in French-speaking Africa and of the sexual

  13. Socially-marketed rapid diagnostic tests and ACT in the private sector: ten years of experience in Cambodia

    PubMed Central

    2011-01-01

    Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemisinin combination therapy (ACT) and others are already facing parasites resistant to artemisinins. In this context, there is a crucial need to improve both access to and targeting of ACT through greater availability of good quality ACT and parasitological diagnosis. This is an issue of increasing urgency notably in the private commercial sector, which, in many countries, plays an important role in the provision of malaria treatment. The Affordable Medicines Facility for malaria (AMFm) is a recent initiative that aims to increase the provision of affordable ACT in public, private and NGO sectors through a manufacturer-level subsidy. However, to date, there is little documented experience in the programmatic implementation of subsidized ACT in the private sector. Cambodia is in the unique position of having more than 10 years of experience not only in implementing subsidized ACT, but also rapid diagnostic tests (RDT) as part of a nationwide social marketing programme. The programme includes behaviour change communication and the training of private providers as well as the sale and distribution of Malarine, the recommended ACT, and Malacheck, the RDT. This paper describes and evaluates this experience by drawing on the results of household and provider surveys conducted since the start of the programme. The available evidence suggests that providers' and consumers' awareness of Malarine increased rapidly, but that of Malacheck much less so. In addition, improvements in ACT and RDT availability and uptake were relatively slow, particularly in more remote areas. The lack of standardization in the survey methods and the gaps in the data highlight the importance of establishing a clear system for monitoring and evaluation for similar initiatives. Despite these limitations, a

  14. Inborn errors of metabolism identified via newborn screening: Ten-year incidence data and costs of nutritional interventions for research agenda planning✰

    PubMed Central

    Therrell, Bradford L.; Lloyd-Puryear, Michele A.; Camp, Kathryn M.; Mann, Marie Y.

    2014-01-01

    Inborn errors of metabolism (IEM) are genetic disorders in which specific enzyme defects interfere with the normal metabolism of exogenous (dietary) or endogenous protein, carbohydrate, or fat. In the U.S., many IEM are detected through state newborn screening (NBS) programs. To inform research on IEM and provide necessary resources for researchers, we are providing: tabulation of ten-year state NBS data for selected IEM detected through NBS; costs of medical foods used in the management of IEM; and an assessment of corporate policies regarding provision of nutritional interventions at no or reduced cost to individuals with IEM. The calculated IEM incidences are based on analyses of ten-year data (2001–2011) from the National Newborn Screening Information System (NNSIS). Costs to feed an average person with an IEM were approximated by determining costs to feed an individual with an IEM, minus the annual expenditure for food for an individual without an IEM. Both the incidence and costs of nutritional intervention data will be useful in future research concerning the impact of IEM disorders on families, individuals and society. PMID:25085281

  15. PREVALENCE OF HELICOBACTER PYLORI TEN YEARS AGO COMPARED TO THE CURRENT PREVALENCE IN PATIENTS UNDERGOING UPPER ENDOSCOPY

    PubMed Central

    FRUGIS, Sandra; CZECZKO, Nicolau Gregori; MALAFAIA, Osvaldo; PARADA, Artur Adolfo; POLETTI, Paula Bechara; SECCHI, Thiago Festa; DEGIOVANI, Matheus; RAMPANAZZO-NETO, Alécio; D´AGOSTINO, Mariza D.

    2016-01-01

    ABSTRACT Background: Helicobacter pylori has been extensively studied since 1982 it is estimated that 50% of the world population is affected. The literature lacks studies that show the change of its prevalence in the same population over time. Aim: To compare the prevalence of H. pylori in 10 years interval in a population that was submitted to upper endoscopy in the same endoscopy service. Method: Observational, retrospective and cross-sectional study comparing the prevalence of H. pylori in two samples with 10 years apart (2004 and 2014) who underwent endoscopy with biopsy and urease. Patients were studied in three consecutive months of 2004, compared to three consecutive months of 2014. The total number of patients was 2536, and 1406 in 2004 and 1130 in 2014. Results: There were positive for H. pylori in 17 % of the sample as a whole. There was a significant decrease in the prevalence from 19.3% in 2004 to 14.1% in 2014 (p<0.005). Conclusion: There was a 5.2% reduction in the prevalence of H. pylori comparing two periods of three consecutive months with 10 years apart in two equivalent population samples. PMID:27759776

  16. Ten years of integrated care: backwards and forwards. The case of the province of Québec, Canada

    PubMed Central

    Vedel, Isabelle; Monette, Michele; Beland, François; Monette, Johanne; Bergman, Howard

    2011-01-01

    Introduction Québec’s rapidly growing elderly and chronically ill population represents a major challenge to its healthcare delivery system, attributable in part to the system’s focus on acute care and fragmented delivery. Description of policy practice Over the past few years, reforms have been implemented at the provincial policy level to integrate hospital-based, nursing home, homecare and social services in 95 catchment areas. Recent organizational changes in primary care have also resulted in the implementation of family medicine groups and network clinics. Several localized initiatives were also developed to improve integration of care for older persons or persons with chronic diseases. Conclusion and discussion Québec has a history of integration of health and social services at the structural level. Recent evaluations of the current reform show that the care provided by various institutions in the healthcare system is becoming better integrated. The Québec health care system nevertheless continues to face three important challenges in its management of chronic diseases: implementing the reorganization of primary care, successfully integrating primary and secondary care at the clinical level, and developing effective governance and change management. Efforts should focus on strengthening primary care by implementing nurse practitioners, developing a shared information system, and achieving better collaboration between primary and secondary care. PMID:21677842

  17. Severe Allergic Reactions to Food in Norway: A Ten Year Survey of Cases Reported to the Food Allergy Register

    PubMed Central

    Namork, Ellen; Fæste, Christiane K.; Stensby, Berit A.; Egaas, Eliann; Løvik, Martinus

    2011-01-01

    The Norwegian Food Allergy Register was established at the Norwegian Institute of Public Health in 2000. The purpose of the register is to gain information about severe allergic reactions to food in Norway and to survey food products in relation to allergen labelling and contamination. Cases are reported on a voluntary basis by first line doctors, and submitted together with a serum sample for specific IgE analysis. The register has received a total of 877 reports from 1 July, 2000 to 31 December, 2010. Two age groups, small children and young adults are over-represented, and the overall gender distribution is 40:60 males-females. The legumes lupine and fenugreek have been identified as two “new” allergens in processed foods and cases of contamination and faults in production of processed foods have been revealed. The highest frequency of food specific IgE is to hazelnuts and peanuts, with a marked increase in reactions to hazelnuts during the last three years. The Food Allergy Register has improved our knowledge about causes and severity of food allergic reactions in Norway. The results show the usefulness of population based national food allergy registers in providing information for health authorities and to secure safe food for individuals with food allergies. PMID:21909296

  18. Two to ten years: developmental trajectories of joint attention in children with ASD who received targeted social communication interventions.

    PubMed

    Gulsrud, Amanda C; Hellemann, Gerhard S; Freeman, Stephanny F N; Kasari, Connie

    2014-04-01

    This study follows 40 children who were participants in a randomized controlled early intervention trial (Kasari et al.) from early childhood (2-5 years of age) to elementary school age (8-10 years). To fully utilize the available longitudinal data, the general linear mixed model was the primary analytical approach. The growth trajectories of joint attention skills (pointing, coordinated joint looking, and showing) and expressive language outcomes in these children were estimated based on five time points during the measurement period. The children were grouped by diagnosis at the last follow-up (autism, autism spectrum disorder (ASD), no diagnosis) and by their original treatment group assignment (joint attention, symbolic play, control), and differences between these groups were evaluated. Results showed that joint attention skills of coordinated joint looking and showing increased over time, and pointing to share interest increased over the first year measured and decreased thereafter. These trajectories were influenced by both original treatment assignment and diagnostic status at follow-up. In addition, a cross-lagged panel analysis revealed a causal relationship between early pointing and later language development. This study highlights the longitudinal and developmental importance of measures of early core deficits in autism, and suggests that both treatment and ASD symptomatology may influence growth in these skills over time.

  19. Ten years after the United Nations General Assembly Special Session (UNGASS): assessing drug problems, policies and reform proposals.

    PubMed

    Reuter, Peter

    2009-04-01

    In 1998 the United Nations General Assembly Special Session resolved that governments would reduce drug production and consumption greatly within 10 years. With that period now elapsed, there is an interest in reviewing how successful this was and considering how drug policy could be improved. The demand for drugs in the world has stabilized mainly as a result of the interaction of epidemic forces, culture and economic development. Supply has become more concentrated and the menu of drugs has changed surprisingly slowly. Drug policy is shifting to a more explicitly tolerant configuration in Europe and a few other countries, but retains its ferocity in most of the world. The most prominent innovations under discussion have limited potential effects (heroin maintenance), have as yet been unproductive of policy interventions ('addiction is a brain disease') or have no political appeal (legalization). The option with the most scope is increased effort at diverting arrested drug users out of criminal justice systems. No prevention, treatment or enforcement strategies have demonstrated an ability to substantially affect the extent of drug use and addiction. The best that government interventions can do is to reduce the damaging consequences of drug use and drug control. More attention should be given to reductions in the intensity of drug enforcement, which has many unintended adverse consequences and yields few of the claimed gains.

  20. Regenerative Treatment of a Cemental Tear Using Enamel Matrix Derivatives: a Ten-Year Follow-up

    PubMed Central

    Schmidlin, Patrick R

    2012-01-01

    A patient presented with chronic periapical periodontitis on tooth 45. The root canal was re-treated and a wide apical perforation was closed with MTA® as an apical plug. At reevaluation six month later, the tooth presented with increased mobility, bleeding on probing and probing pocket depths of 9 mm. Despite good periapical healing radio graphically, the tooth showed signs of localized marginal bone loss that was diagnosed as being due to a cemental fracture. The tooth was splinted, a muco-periostal flap was raised and the fragment of cementum was removed. The defect was treated in a regenerative approach, using enamel matrix derivatives (EMD). Six month after therapy, the probing pocket depths decreased to values of ≤ 3 mm and a defect fill was radiographically visible. The 10-year follow up showed a stable situation. It can be concluded that the occurrence of a local delamination of the root surface may contribute to the development of plaque-induced periodontal destruction. Its removal and the regenerative conditioning of the root surface with EDTA and EMD may result in a, at least partial, resolution of the problem and regeneration of bone at the affected the site. PMID:23056160

  1. Mechanisms of human natural resistance to HIV: a summary of ten years of research in the Colombian population.

    PubMed

    Rugeles, María T; Velilla, Paula A; Montoya, Carlos J

    2011-06-01

    The natural history of human immunodeficiency virus type-1 (HIV-1) infection is a complex and variable process that, similarly to other infections, has clearly demonstrated the existence of mechanisms of human natural resistance. The resistance either inhibits the establishment of infection or delays disease progression. When there is continuous exposure to infectious viral particles, several genetic and immunological mechanisms are essential to lead to resistance to HIV-1 infection/progression. The objective of this manuscript was to review the different mechanisms so far proposed to be responsible for HIV-1 resistance and to present the main results derived from 10 years of research in this area among Colombian subjects. In particular, this review focuses on determining the mechanisms involved in the protection of a group of individuals repeatedly exposed to the virus but who remained exempt of serological and clinical evidence of HIV-1 infection. Although the studies carried out in our research group corroborated the protective role of some of the previously proposed mechanisms of protection, ongoing research worldwide has made it clear that the phenomenon of human natural resistance depends on multiple factors with an important genetic influence, and only multicenter studies involving individuals with different genetic backgrounds may determine more universal mechanisms of resistance. Increasing our knowledge in this field will contribute to the development of novel preventive and therapeutic measures.

  2. The impact of ten years at -20°C on gas exchange in five lichen species.

    PubMed

    Larson, D W

    1989-01-01

    Rates of net CO2 exchange in five sympatric species of Umbilicaria were measured after 10 years at-20°C. During that time, the lichens had been at either a high (saturated) or a low (air-dry) water content. The results showed an immediate, return to normal rates of gas exchange for air-dried then frozen U.vellea. Rates returned to normal for air-dried U. deusta within four days. The three other species studied, U. mammulata, U. papulosa and U. muhlenbergii showed intermediate responses. Water saturated then frozen thalli of U. vellea were irreparably damaged after 10 years; even fungal respiration was severely impaired. In U. mammulata, U. papulosa and U. muhlenbergii, photosynthesis was eliminated but fungal respiration rates were not influenced. In contrast to this, water saturated then frozen thalli of U. deusta showed a nearly equal photosynthetic capacity to the original rates following 10 years at -20°C. In all cases the magnitude of the effect of the long-term subzero treatment correlated well with the known distribution patterns of the lichens in the field.

  3. Congenital Kyphoscoliosis in Monozygotic Twins: Ten-Year Follow-up Treated by Posterior Vertebral Column Resection (PVCR)

    PubMed Central

    Chang, Dong-Gune; Yang, Jae Hyuk; Lee, Jung-Hee; Kim, Young-Hoon; Kim, Jin-Hyok; Suh, Seung-Woo; Ha, Kee-Yong; Suk, Se-Il

    2016-01-01

    Abstract The etiology of congenital scoliosis and its development remains unclear and has not yet been fully identified, even there are theories that congenital scoliosis could be derived from the failure of formation or failure of segmentation, which are etiologically heterogeneous with genetic, epigenetic, and environmental factors contributing to their occurrence. We reported a case of long-term follow-up after posterior vertebral column resection (PVCR) in both identical twins with similar congenital kyphoscoliosis at thoracolumbar levels. Twin I had been noticed by his parents to have asymmetry of his back at age 5 years, but no treatment was given. Twin II was first noticed to have a spinal problem at 11 years of age by his parents. Overtime, spine of both twins became further deviated to the left with kyphosis and was referred to our hospital. Both monozygotic twins were treated by PVCR and satisfactory results were demonstrated at 10-year follow-up. This case is the first report on the surgical treatment with PVCR, almost simultaneously, in both identical twins who had similar congenital vertebral anomalies causing kyphoscoliosis. Both identical twins with congenital kyphoscoliosis had undergone surgical correction by PVCR, anterior support with a mesh cage and posterior fusion using pedicle screws at the age of 14 years and achieved a satisfactory correction and a stable spine without curve progression with 10-year follow-up. PMID:27124052

  4. Sexual orientation and relationship choice in borderline personality disorder over ten years of prospective follow-up.

    PubMed

    Reich, D Bradford; Zanarini, Mary C

    2008-12-01

    The purpose of this study was to assess the prevalence of homosexuality/ bisexuality and same-sex relationships in a sample of 362 hospitalized subjects, 290 with borderline personality disorder (BPD) and 72 comparison subjects with other personality disorders. At baseline and at five contiguous 2-year follow-up intervals, subjects meeting DIB-R and DSM-III-R criteria for BPD or at least one other personality disorder were interviewed using a semi-structured interview about their sexual orientation and the gender of intimate partners. Subjects with BPD were significantly more likely than comparison subjects to report homosexual or bisexual orientation and intimate same-sex relationships. There were no significant differences between male and female borderline subjects in prevalence of reported homosexual or bisexual orientation or in prevalence of reported same-sex relationships. Subjects with BPD were significantly more likely than comparison subjects to report changing the gender of intimate partners, but not sexual orientation, at some point during the follow-up period. A reported family history of homosexual or bisexual orientation was a significant predictor of an aggregate outcome variable assessing homosexual/bisexual orientation and/or same sex relationship in borderline subjects. Results of this study suggest that same-gender attraction and/or intimate relationship choice may be an important interpersonal issue for approximately one-third of both men and women with BPD.

  5. Long Term Outcomes in Stress Echocardiography: Ten Year Follow up of a Cohort in a Single Centre

    PubMed Central

    Ashrafi, Reza; McKay, Ewan; Jones, Julia; Amadi, Aham

    2012-01-01

    Backgroud The high service burden for acute admissions and referrals via rapid access chest pain clinics for evaluation of possible coronary artery disease means that many patients are now undergoing an investigation such as stress echocardiography as part of their evaluation. We aimed to see if the reassurance provided by negative stress echocardiography correlates with long-term event free survival. Methods A cohort of all patients who were referred at a single centre for stress echocardiography for diagnosis of coronary artery disease between January 1st 1999 and December 31st 2000 were followed up at least 10 years following theirs stress echocardiogram for further major cardiovascular events and mortality. Results A total of 64 patients were identified where records could be obtained for analysis. There were 16 positive scans, 37 negative scans and 11 inconclusive scans. The indeterminacy rate of scans was 17%, the sensitivity rate for detecting significant disease as indexed to invasive angiography was 88 % and the specificity rate compared with angiography was 75%. There were no myocardial infarctions or new diagnoses of heart failure in the negative echocardiogram group. There were seven deaths in the total population and only one death from cardiovascular causes in the negative echocardiogram group. Conclusion Stress echocardiography even in this small group predicts long-term outcomes as well as invasive coronary angiography.

  6. Ten years maintaining MACAO-VLTI units in operation in the Very Large Telescope at Paranal Observatory

    NASA Astrophysics Data System (ADS)

    Salgado, F.; Hudepohl, G.

    2016-07-01

    More than 10 years have already passed since the first Multiple Application Curvature Adaptive Optics (MACAO) facilities got the first light in UT2 the 18th of April, 2003, in the Very Large Telescope (VLT) at Paranal Observatory. The achievable image sharpness of a ground-based telescope is normally limited by the effect of atmospheric turbulence. However, with Adaptive Optics (AO) techniques, this major drawback can be overcome so that the telescope produces images that are as sharp as theoretically possible, i.e., as if they were taken from space. [1] The intention of this document is summarize in few pages some highlights related with the activities needed to keep MACAO units in operation. Some statistics of problems based in Action Remedy tool is included, showing how through these years the number of problems has been reduced, even when there are still some unsolved ones. Some lessons have been learned and there are others one to learn. Corrective and predictive maintenance performed are shown too like the current measurements, transfer functions measurements, thermography pictures, health checks measuring interaction matrix and flat vectors to detect dead APDs or short circuits in the DM, etc. Some forced interventions are included as well like the removal of the cabinets from Coude rooms to avoid that acoustic noise and vibrations perturb the operations, the deformable mirrors reached by cooling leaks and a mirror that got rusty are shown too. Well knowledge of the system, good interaction between different disciplines groups to perform corrective and preventive maintenance seems to be key aspects of keeping it under control and operative during all these years leading to this good result.

  7. Ten years of elemental atmospheric metal fallout and Pb isotopic composition monitoring using lichens in northeastern France

    NASA Astrophysics Data System (ADS)

    Cloquet, Christophe; Estrade, Nicolas; Carignan, Jean

    2015-09-01

    We report on the chemical and Pb isotopic compositions of epiphytic lichens collected from small tree branches in the urban area of the city of Metz (NE France). Lichens were collected in five different years between 2001 and 2009. The data are first compared year to year in order to document any temporal change and trend in metal atmospheric fallout. The area studied was then subdivided into different zones on the basis of land use (urban, suburban, rural and industrial) in order to determine potential spatial gradients. The median concentrations and enrichment factors (EF, normalized to Al) of Pb and other metals (Cu, Zn, Cd, Ni, Cr, Hg, Fe) in lichens from the urban, suburban, and rural zones show no systematic variation between 2001 and 2008. However, the metal EFs show spatial variation and are generally highest in the urban area and lowest in the rural area. Lichens within the industrial zone (collected in 2009), which is dominated by steel industries, are richest in Al, Fe, Cr, Pb, and Zn. Although the Al concentration is high in these lichens, the EFs for the cited metals are several times higher than those measured in lichens from the other three zones. No significant differences were noted for Hg, Cd, Cu and or Ni. Pb isotopic compositions measured in lichens may be highly variable from year to year and from zone to zone. The variation is primarily interpreted to result from mixing between: (i) Pb added to gasoline (and recycled through re-emission of road dust in the atmosphere); (ii) regional industrial Pb from long-range transportation and/or mixed with urban Pb; and (iii) local industrial Pb. The median isotopic compositions of individual zones are distinct, suggesting variable mixing of these three sources. The annual variations show that 2001 was most affected by gasoline Pb, whereas 2003 and 2006 were more affected by the local steel industry.

  8. Ten years of cerebral venous thrombosis: male gender and myeloproliferative neoplasm is associated with thrombotic recurrence in unprovoked events.

    PubMed

    Lim, H Y; Ng, C; Donnan, G; Nandurkar, H; Ho, Prahlad

    2016-10-01

    Cerebral venous thrombosis (CVT) is a rare venous thrombotic event. We review our local experience in the management of CVT in comparison to other venous thromboembolism (VTE) with specific focus on risk factors for thrombotic recurrence. Retrospective evaluation of consecutive CVT presentations from January 2005 to June 2015, at two major tertiary hospitals in Northeast Melbourne, Australia. This population was compared to a separate audit of 1003 consecutive patients with DVT and PE. Fifty-two patients (30 female, 22 male) with a median age of 40 (18-83) years, presented with 53 episodes of CVT. Twenty-nine episodes (55 %) were associated with an underlying risk factor, with hormonal risk factors in females being most common. The median duration of anticoagulation was 6 months with 11 receiving life-long anticoagulation. Eighty-one percent had residual thrombosis on repeat imaging, which was not associated with recurrence at the same or distant site. Nine (17 %) had CVT-related haemorrhagic transformation with two resultant CVT-related deaths (RR 22.5; p = 0.04). All three VTE recurrences occured in males with unprovoked events (RR 18.2; p = 0.05) who were subsequently diagnosed with myeloproliferative neoplasm (MPN). Compared to the non-cancer VTE population, non-cancer CVT patients were younger, had similar rate of provoked events and VTE recurrence, although with significantly higher rate of MPN diagnosis (RR 9.30 (2.29-37.76); p = 0.002) CVT is a rare thrombotic disorder. All recurrences in this audit occurred in male patients with unprovoked events and subsequent diagnosis of MPN, suggesting further evaluation for MPN may be warranted in patients with unprovoked CVT.

  9. Ten years of experience in clinicopathologic characteristics, treatment and outcome of patients with nasopharyngeal pathologies in Yazd, Iran

    PubMed Central

    Binesh, Fariba; Shajari, Ahmad; Abdollahi, Somayeh; Behniafard, Nasim

    2016-01-01

    Introduction Although there are some studies regarding the clinical characteristics and outcome of nasopharyngeal tumors, one such study from Iran has not been reported to date. This study aimed to evaluate the clinical features, treatment, and consequences of nasopharyngeal lesions. Methods In this cross sectional study, we conducted a retrospective review of patients who were diagnosed with nasopharyngeal pathologies and treated at Shahid Sadoughi Hospital and Shahid Ramazanzadeh Radiotherapy Center in Yazd, Iran, over a period of 10 years (from 2005 to 2014). The variables in the study were the patient’s hospital registration number, date, name, age, gender, address, topography, clinical symptoms, morphology, stage, types of treatment, and survival for each subject. Survival data were analyzed using Kaplan-Meier estimates, and multivariate analysis was performed using the Cox regression method. Statistical analyses were performed using IBM-SPSS, version 22. Results In the study, there were 123 patients, 85 males and 38 females, who had nasopharyngeal lesions. The mean age at diagnosis was 41.51 ± 20.33 years. There were 83 patients with malignant neoplasms and 40 patients with non-malignant lesions. The most common malignant tumor was nasopharyngeal carcinoma, and the most common benign lesion was angiofibroma. Survival analysis was performed for the 83 patients who had malignant neoplasms, and survival was found to be 94.5 ± 4.32 months. There were significant differences in survival based on the stage of the disease, histological type, and the type of treatment (p = 0.001, 0.02, and 0.003, respectively). Conclusion In our institutional study, malignant tumors were more common than benign lesions. Patients with nasopharyngeal carcinoma presented relatively late and at an advanced stage. Regular follow-up is necessary for early detection, recurrence, or metastases of malignant tumors. PMID:27957307

  10. Ten years after entry into force of the Stockholm Convention: What do air monitoring data tell about its effectiveness?

    PubMed

    Wöhrnschimmel, Henry; Scheringer, Martin; Bogdal, Christian; Hung, Hayley; Salamova, Amina; Venier, Marta; Katsoyiannis, Athanasios; Hites, Ronald A; Hungerbuhler, Konrad; Fiedler, Heidelore

    2016-10-01

    More than a decade ago, the Stockholm Convention on Persistent Organic Pollutants (POPs), one of the multilateral environmental agreements administered by the United Nations Environment Programme (UNEP), entered into force. The objective of this Convention is to protect human health and the environment by controlling the releases of POPs. According to its Article 16, the effectiveness of the Stockholm Convention shall be evaluated using comparable monitoring data on the presence of POPs as well as their regional and global environmental transport. Here, we present a time series analysis on atmospheric POP concentrations from 15 monitoring stations in North America and Europe that provide long-term data and have started operations between 1990 and 2003. We systematically searched for temporal trends and significant structural changes in temporal trends that might result from the provisions of the Stockholm Convention. We find that such structural changes do occur, but they are related mostly to effects of national regulations enforced prior to the implementation of the Stockholm Convention, rather than to the enforcement of the provisions laid out in the Convention. One example is that concentrations of polychlorinated biphenyls, many of which started to decrease rapidly during the 1990s. Also effects of chemical transport and fate, for instance the re-volatilization of POPs from secondary sources, are thought to be a cause of some of the observed structural changes. We conclude that a decade of air monitoring data has not been sufficient for detecting general and statistically significant effects of the Stockholm Convention. Based on these lessons, we present recommendations for the future operation of existing monitoring programs and advocate for a stricter enforcement of the provisions of the Stockholm Convention, in the current absence of proof for its effectiveness.

  11. Ten years of elemental atmospheric metal fallout and Pb isotopic composition monitoring using lichens in north-eastern France

    NASA Astrophysics Data System (ADS)

    Cloquet, Christophe; Estrade, Nicolas

    2016-04-01

    We report on the chemical and Pb isotopic compositions of epiphytic lichens collected from small tree branches in the urban area of the city of Metz (NE France). Lichens were collected in five different years between 2001 and 2009. The data are first compared year to year in order to document any temporal changes and trends in metal atmospheric fallout. The area studied was then subdivided into different zones on the basis of land-use (urban, suburban, rural and industrial) in order to determine potential spatial gradients. The median concentrations and enrichment factors (EF, normalized to Al) of Pb and other metals (Cu, Zn, Cd, Ni, Cr, Hg, Fe) in lichens from the urban, suburban, and rural zones show no systematic variation between 2001 and 2008. However, the metal EFs show spatial variation and are generally highest in the urban area and lowest in the rural area. Lichens within the industrial zone (collected in 2009), which is dominated by steel industries, are richest in Al, Fe, Cr, Pb, and Zn. Although the Al concentration is high in these lichens, the EFs for the cited metals are several times higher than those measured in lichens from the other three zones. No significant differences were noted for Hg, Cd, Cu and or Ni. Lead isotopic compositions measured in lichens may be highly variable from year to year and from zone to zone. The variation is primarily interpreted to result from mixing between: (i) Pb added to gasoline (and recycled through re-emission of road dust in the atmosphere); (ii) regional industrial Pb from long-range transportation and/or mixed with urban Pb; and (iii) local industrial Pb. The median isotopic compositions of individual zones are distinct, suggesting variable mixing of these three sources. The annual variations show that 2001 was most affected by gasoline Pb, whereas 2003 and 2006 were more affected by the local steel industry.

  12. The pollution removal and stormwater reduction performance of street-side bioretention basins after ten years in operation.

    PubMed

    Lucke, Terry; Nichols, Peter W B

    2015-12-01

    This study evaluated the pollution removal and hydrologic performance of five, 10-year old street-side bioretention systems. The bioretention basins were subjected to a series of simulated rainfall events using synthetic stormwater. Four different pollution concentrations were tested on three of the bioretention basins. The four concentrations tested were: A) no pollution; B) typical Australian urban pollutant loads; C) double the typical pollution loads, and; D) five times the typical pollution loads. Tests were also undertaken to determine the levels of contaminant and heavy metals build-up that occurred in the filter media over the 10 year operational life of the bioretention systems. Although highly variable, the overall hydrological performance of the basins was found to be positive, with all basins attenuating flows, reducing both peak flow rates and total outflow volumes. Total suspended solids removal performance was variable for all tests and no correlation was found between performance and dosage. Total nitrogen (TN) removal was positive for Tests B, C and D. However, the TN removal results for Test A were found to be negative. Total phosphorus (TP) was the only pollutant to be effectively removed from all basins for all four synthetic stormwater tests. The study bioretention basins were found to export pollutants during tests where no pollutants were added to the simulated inflow water (Test A). Heavy metal and hydrocarbon testing undertaken on the bioretention systems found that the pollution levels of the filter media were still within acceptable limits after 10 years in operation. This field study has shown bioretention basin pollution removal performance to be highly variable and dependant on a range of factors including inflow pollution concentrations, filter media, construction methods and environmental factors. Further research is required in order to fully understand the potential stormwater management benefits of these systems.

  13. A ten-year analysis of the traumatic maxillofacial and brain injury patient in Amsterdam: incidence and aetiology.

    PubMed

    Salentijn, Erik G; Peerdeman, Saskia M; Boffano, Paolo; van den Bergh, Bart; Forouzanfar, Tymour

    2014-09-01

    In the literature it is questioned if the presence of maxillofacial trauma is associated with the presence of brain injury. The aim of this study is to present a 10-year retrospective study of the incidence and aetiology of maxillofacial trauma associated with brain injury that required both oral and maxillofacial and neurosurgical intervention during the same hospital stay. Forty-seven patients from a population of 579 trauma patients undergoing maxillofacial surgery were identified. The main cause of injury was road traffic collision, followed by falls. Interpersonal violence correlated less well with traumatic brain injury. Most of the patients were males, aged 20-39 years. Frontal sinus fractures were the most common maxillofacial fractures (21.9%) associated with neurosurgical input, followed by mandibular fractures and zygomatic complex fractures. In the general maxillofacial trauma population, frontal sinus fractures were only found in 2.2% of the cases. At presentation to the Emergency Department the majority of the patients were diagnosed with severe traumatic brain injury and a Marshall CT class 2. Intracranial pressure monitoring was the most common neurosurgical intervention, followed by reconstruction of a bone defect and haematoma evacuation. Although it is a small population, our data suggest that maxillofacial trauma does have an association with traumatic brain injury that requires neurosurgical intervention (8.1%). In comparison with the overall maxillofacial trauma population, our results demonstrate that frontal sinus fractures are more commonly diagnosed in association with brain injury, most likely owing to the location of the impact of the trauma. In these cases the frontal sinus seems not specifically to act as a barrier to protect the brain. This report provides useful data concerning the joint management of oral and maxillofacial surgeons and neurosurgeons for the treatment of cranio-maxillofacial trauma and brain injury patients in

  14. A review of the activities of the IAG working group on geomorphosites over the last ten years

    NASA Astrophysics Data System (ADS)

    Reynard, Emmanuel; Coratza, Paola

    2013-04-01

    During the last two decades a renewed interest emerged in the scientific community for geoheritage, geoconservation and geotourism research. This was the reason for the International Association of Geomorphologists (IAG) for creating a specific working group on geomorphosites in 2001, with the aim to improve knowledge and scientific research on the definition, assessment, cartography, promotion and conservation of geomorphological heritage. The working group is chaired by the two authors, experiences were shared during several workshops and international conferences, and results were collected in several special publications (http://www.geomorph.org/wg/wggs.html). Several intensive courses for Master and PhD students were also organized and a book was published, dedicated particularly to Master and PhD students working on geomorphosite issues (Reynard et al., 2009). This contribution proposes a review of the working group activities since 2001 that focused on four main domains: (1) Definition and conceptualization. Geomorphosites are a type of geosite that is portions of the geosphere that present a particular importance for the comprehension of the Earth's history. Geomorphosites have to be considered as the result of human valuation. Conceptualization related to the value of geomorphosites is still in course. Nevertheless, three groups of values can be demonstrated: the scientific value (that is the interest of sites for Earth history and for the history and epistemology of geomorphology), several additional values (aesthetic, ecological, and cultural in a broad sense), and use and management values, that can be divided in three groups (educational value, economic value, including the tourist value, and protection). The scientific and additional value can be considered as intrinsic values, whereas the management and use value are to be related to extrinsic or societal values. (2) Assessment. Several methods, based on the measurement of specific features of

  15. Ten years of OMI observations: scientific highlights and impacts on the new generation of UV/VIS satellite instrumentation

    NASA Astrophysics Data System (ADS)

    Levelt, Pieternel; Veefkind, Pepijn; Bhartia, Pawan; Joiner, Joanna; Tamminen, Johanna; OMI Science Team

    2014-05-01

    contributes to several operational services, including volcanic plume warning systems for aviation, UV forecasts and the air quality forecasts. In this invited talk an overview will be given of unique findings and new scientific results based on OMI data over the last 10 years and which unique OMI instrument features are recurring in the new generation of UV/VIS satellite instrumentation in Europe, USA and Asia.

  16. A Ten-Year Retrospective Look at the NSF/GEO Opportunities for Enhancing Diversity in the Geosciences (OEDG) Program

    NASA Astrophysics Data System (ADS)

    Karsten, J. L.

    2013-12-01

    The Opportunities for Enhancing Diversity in the Geosciences (OEDG) program - established in 2002 by the National Science Foundation's Directorate for Geosciences (GEO) - has been a mainstay in GEO's efforts to broaden participation of traditionally underrepresented minorities in the geosciences. The primary goal of the OEDG program has been to engage a diverse population of students in learning about - and pursuing advanced degrees and careers in - the geosciences. Raising public awareness of the importance and relevance of the geosciences among diverse audiences has been a secondary goal. During the past decade, the OEDG program has supported a variety of planning grants, proof-of-concept projects, and larger full-scale implementation efforts across the U.S. These projects have contributed a rich array of culturally-tailored resources for learning about geoscience career pathways and opportunities to participate in geoscience research experiences. OEDG has also developed networking and mentoring programs tailored for diverse student audiences, as well as the educators who work with them, and has helped to build capacity in the geosciences at minority-serving institutions. Perhaps the most important legacy of the OEDG program has been the establishment of an enthusiastic and effective community of educators, administrators, students and organizations dedicated to increasing diversity in the geosciences. Evaluation data collected for individual OEDG projects has helped to improve the impact of specific projects and increase our understanding of which approaches are more successful in achieving OEDG program goals. In addition, GEO has supported a decade-long, program-wide evaluation of the OEDG portfolio through a contract to the American Institutes for Research (AIR). Synthesis of results from both the project- and program-level evaluation activities has identified evidence-based 'best practices' that are essential for achieving success in broadening participation

  17. Ten years of antibiotic consumption in ambulatory care: Trends in prescribing practice and antibiotic resistance in Austria

    PubMed Central

    2009-01-01

    Background The primary aims of this study were (i) to determine the quantity and pattern of antibiotic use in Austria between 1998 and 2007 and (ii) to analyze antibiotic resistance rates in relation to antibiotic consumption in important clinical situations in order to provide data for empirical therapeutic regimens for key indications. Methods Consumption data and resistance data were obtained via the Austrian surveillance networks European Antimicrobial Resistance Surveillance System (EARSS) and European Surveillance on Antimicrobial Consumption (ESAC). The EARSS collects data on isolates from blood and cerebrospinal fluid obtained predominantly in the hospital setting. The Anatomical Therapeutic Chemical (ATC) classification and the Defined Daily Dose (DDD) measurement units were assigned to the data. The number of DDDs and packages per 1,000 inhabitants (PID) were used to calculate the level of antibiotic consumption. Antibiotic resistance was expressed in resistance rates, i.e., the percentage of resistant isolates compared to all isolates of one bacterial species. Results The overall antibiotic consumption measured in DIDs increased by 10% between 1998 and 2007, whereas PIDs decreased by 3%. The consumption of substances within the drug utilization 90% segment (measured in PID) increased for ciprofloxacin (+118.9), clindamycin (+76.3), amoxicillin/clavulanic acid (+61.9%), cefpodoxime (+31.6), azithromycin (+24.7); and decreased for erythromycin (-79.5%), trimethoprim (-56,1%), norfloxacin (-48.8%), doxycycline (-44.6), cefaclor (-35.1%), penicillin (-34.0%), amoxicillin (-22.5), minocycline (-21.9%) and clarithromycin (-9.9%). Starting in 2001, an increase in the percentage of invasive E. coli isolates resistant to aminopenicillins (from 35% to 53%), fluoroquinolones (from 7% to 25.5%) and third-generation cephalosporins (from 0% to 8.8%) was observed. The percentage of nonsusceptible or intermediate penicillin-resistant pneumococcal isolates remained

  18. Ten-year variability in ecosystem water use efficiency in an oak-dominated temperate forest under a warming climate

    SciTech Connect

    Xie, Jing; Chen, Jiquan; Sun, Ge; Zha, Tianshan; Yang, Bai; Chu, Housen; Liu, Junguo; Wan, Shiqiang; Zhou, Caixian; Ma, Hong; Bourque, Charles; Shao, Changliang; John, Ranjeet; Ouyang, Zutao

    2016-01-07

    The impacts of extreme weather events on water-carbon (C) coupling and ecosystem-scale water use efficiency (WUE) over a long term are poorly understood. We analyzed the changes in ecosystem water use efficiency (WUE) from 10 years of eddy-covariance measurements (2004-2013) over an oak-dominated temperate forest in Ohio, USA. The aim was to investigate the long-term response of ecosystem WUE to measured changes in site-biophysical conditions and ecosystem attributes. The oak forest produced new plant biomass of 2.5 +/- 0.2 gC kg(-1) of water loss annually. Monthly evapotranspiration (ET) and gross ecosystem production (GEP) were tightly coupled over the 10-year study period (R-2=0.94). Daily WUE had a linear relationship with air temperature (T-a) in low-temperature months and a unimodal relationship with T-a in high-temperature months during the growing season. On average, daily WUE ceased to increase when T-a exceeded 22 degrees C in warm months for both wet and dry years. Monthly WUE had a strong positive linear relationship with leaf area index (LAI), net radiation (R-n), and T-a and weak logarithmic relationship with water vapor pressure deficit (VPD) and precipitation (P) on a growing-season basis. When exploring the regulatory mechanisms on WUE within each season, spring LAI and P, summer R-n and T-a, and autumnal VPD and R-n were found to be the main explanatory variables for seasonal variation in WUE. The model developed in this study was able to capture 78% of growing-season variation in WUE on a monthly basis. The negative correlation between WUE and A in spring was mainly due to the high precipitation amounts in spring, decreasing GEP and WUE when LAI was still small, adding ET being observed to increase with high levels of evaporation as a result of high SWC in spring. Summer WUE had a significant decreasing trend across the 10 years mainly due to the combined effect of seasonal drought and increasing potential and available energy increasing ET, but

  19. Ten-year variability in ecosystem water use efficiency in an oak-dominated temperate forest under a warming climate

    DOE PAGES

    Xie, Jing; Chen, Jiquan; Sun, Ge; ...

    2016-01-07

    The impacts of extreme weather events on water-carbon (C) coupling and ecosystem-scale water use efficiency (WUE) over a long term are poorly understood. We analyzed the changes in ecosystem water use efficiency (WUE) from 10 years of eddy-covariance measurements (2004-2013) over an oak-dominated temperate forest in Ohio, USA. The aim was to investigate the long-term response of ecosystem WUE to measured changes in site-biophysical conditions and ecosystem attributes. The oak forest produced new plant biomass of 2.5 +/- 0.2 gC kg(-1) of water loss annually. Monthly evapotranspiration (ET) and gross ecosystem production (GEP) were tightly coupled over the 10-year studymore » period (R-2=0.94). Daily WUE had a linear relationship with air temperature (T-a) in low-temperature months and a unimodal relationship with T-a in high-temperature months during the growing season. On average, daily WUE ceased to increase when T-a exceeded 22 degrees C in warm months for both wet and dry years. Monthly WUE had a strong positive linear relationship with leaf area index (LAI), net radiation (R-n), and T-a and weak logarithmic relationship with water vapor pressure deficit (VPD) and precipitation (P) on a growing-season basis. When exploring the regulatory mechanisms on WUE within each season, spring LAI and P, summer R-n and T-a, and autumnal VPD and R-n were found to be the main explanatory variables for seasonal variation in WUE. The model developed in this study was able to capture 78% of growing-season variation in WUE on a monthly basis. The negative correlation between WUE and A in spring was mainly due to the high precipitation amounts in spring, decreasing GEP and WUE when LAI was still small, adding ET being observed to increase with high levels of evaporation as a result of high SWC in spring. Summer WUE had a significant decreasing trend across the 10 years mainly due to the combined effect of seasonal drought and increasing potential and available energy increasing

  20. Ten-Year Locoregional Recurrence Risks in Women With Nodal Micrometastatic Breast Cancer Staged With Axillary Dissection

    SciTech Connect

    Lupe, Krystine; Truong, Pauline T.; Alexander, Cheryl; Speers, Caroline; Tyldesley, Scott

    2011-12-01

    Purpose: To compare the locoregional recurrence (LRR) rates in patients with nodal mirometastases (pNmic) with those in patients with node-negative (pN0) and macroscopic node-positive (pNmac) breast cancer; and to evaluate the LRR rates according to locoregional treatment of pNmic disease. Methods and Materials: The subjects were 9,616 women diagnosed between 1989 and 1999 with Stage pT1-T2, pN0, pNmic, or pNmac, M0 breast cancer. All women had undergone axillary dissection. The Kaplan-Meier local recurrence, regional recurrence, and LRR rates were compared among those with pN0 (n = 7,977), pNmic (n = 490) and pNmac (n = 1,149) and according to locoregional treatment. Multivariate analysis was performed to identify the significant factors associated with LRR. Results: The median follow-up was 11 years. The 10-year Kaplan-Meier recurrence rate in the pN0, pNmic, and pNmac cohorts was 6.1%, 6.8%, and 8.7% for local recurrence; 3.1%, 6.2%, and 10.3% for regional recurrence; and 8.0%, 11.6%, and 15.2% for LRR, respectively (all p < .001). In the pNmic patients, the 10-year regional recurrence rate was 6.4% with breast-conserving surgery plus breast radiotherapy (RT), 5.4% with breast-conserving surgery plus locoregional RT, 4.6% with mastectomy alone, 11.1% with mastectomy plus chest wall RT, and 10.7% with mastectomy plus locoregional RT. In patients with pNmic disease and age <45 years, Grade 3 histologic features, lymphovascular invasion, nodal ratio >0.25, and estrogen receptor-negative disease, the 10-year LRR rates were 15-20%. On multivariate analysis of the entire cohort, pNmic was associated with greater LRR than Stage pN0 (hazard ratio [HR], 1.6; p = .002). On multivariate analysis of pNmic patients only, age <45 years was associated with significantly greater LRR (HR, 1.9; p = .03), and trends for greater LRR were observed with a nodal ratio >0.25 (HR, 2.0; p = .07) and lymphovascular invasion (HR, 1.7; p = .07). Conclusion: Women with pNmic had a greater

  1. Ten years of MIPAS measurements with ESA Level 2 processor V6 - Part 1: Retrieval algorithm and diagnostics of the products

    NASA Astrophysics Data System (ADS)

    Raspollini, P.; Carli, B.; Carlotti, M.; Ceccherini, S.; Dehn, A.; Dinelli, B. M.; Dudhia, A.; Flaud, J.-M.; López-Puertas, M.; Niro, F.; Remedios, J. J.; Ridolfi, M.; Sembhi, H.; Sgheri, L.; von Clarmann, T.

    2013-09-01

    The MIPAS (Michelson Interferometer for Passive Atmospheric Sounding) instrument on the Envisat (Environmental satellite) satellite has provided vertical profiles of the atmospheric composition on a global scale for almost ten years. The MIPAS mission is divided in two phases: the full resolution phase, from 2002 to 2004, and the optimized resolution phase, from 2005 to 2012, which is characterized by a finer vertical and horizontal sampling attained through a reduction of the spectral resolution. While the description and characterization of the products of the ESA processor for the full resolution phase has been already described in previous papers, in this paper we focus on the performances of the latest version of the ESA (European Space Agency) processor, named ML2PP V6 (MIPAS Level 2 Prototype Processor), which has been used for reprocessing the entire mission. The ESA processor had to perform the operational near real time analysis of the observations and its products needed to be available for data assimilation. Therefore, it has been designed for fast, continuous and automated analysis of observations made in quite different atmospheric conditions and for a minimum use of external constraints in order to avoid biases in the products. The dense vertical sampling of the measurements adopted in the second phase of the MIPAS mission resulted in sampling intervals finer than the instantaneous field of view of the instrument. Together with the choice of a retrieval grid aligned with the vertical sampling of the measurements, this made ill-conditioned the retrieval problem of the MIPAS operational processor. This problem has been handled with minimal changes to the original retrieval approach but with significant improvements nonetheless. The Levenberg-Marquardt method, already present in the retrieval scheme for its capability to provide fast convergence for nonlinear problems, is now also exploited for the reduction of the ill-conditioning of the inversion. An

  2. Ten years of MIPAS measurements with ESA Level 2 processor V6 - Part I: retrieval algorithm and diagnostics of the products

    NASA Astrophysics Data System (ADS)

    Raspollini, P.; Carli, B.; Carlotti, M.; Ceccherini, S.; Dehn, A.; Dinelli, B. M.; Dudhia, A.; Flaud, J.-M.; López-Puertas, M.; Niro, F.; Remedios, J. J.; Ridolfi, M.; Sembhi, H.; Sgheri, L.; von Clarmann, T.

    2013-01-01

    The MIPAS instrument on the ENVISAT satellite has provided vertical profiles of the atmospheric composition on a global scale for almost ten years. The MIPAS mission is divided in two phases, the full resolution phase, from 2002 to 2004, and the optimized resolution phase, from 2005 to 2012, which is characterized by a finer vertical and horizontal sampling attained through a reduction of the spectral resolution. While the description and characterization of the products of the ESA processor for the full resolution phase has been already described in previous papers, in this paper we focus on the performances of the latest version of the ESA processor, named ML2PP V6, which has been used for reprocessing the entire mission. The ESA processor had to perform the operational near real time analysis of the observations and its products needed to be available for data assimilation. Therefore, it has been designed for fast, continuous and automated analysis of observations made in quite different atmospheric conditions and for a minimum use of external constraints in order to avoid biases in the products. The dense vertical sampling of the measurements adopted in the second phase of the MIPAS mission resulted in sampling intervals finer than the instantaneous field of view of the instrument. Together with the choice of a retrieval grid aligned with the vertical sampling of the measurements, this made ill-conditioned the retrieval formalism of the MIPAS operational processor. This problem has been handled with minimal changes to the original retrieval approach but with significant improvements nonetheless. The Levenberg-Marquardt method, already present in the retrieval scheme for its capability to provide fast convergence for non-linear problems, is now also exploited for the reduction of the ill-conditioning of the inversion. An expression specifically designed for the regularizing Levenberg-Marquardt method has been implemented for the computation of the covariance

  3. Ten years of continuous monitoring of soil CO2 flux: results and implications from the first geochemical monitoring network on Mount Etna.

    NASA Astrophysics Data System (ADS)

    Liuzzo, Marco; Gurrieri, Sergio; Giuffrida, Giovanni; Gaetano, Giudice; Cappuzzo, Santino

    2013-04-01

    Throughout the Mediterranean area, Mt. Etna is well known for its frequent eruptions and considerable lava flows, being, among all of the basaltic volcanoes, one of the most active in the world. The frequent activity of the last two decades has induced the scientific community and the Civil Defence to pay more attention to the surveillance of the volcano and, in view of this, a diverse range of monitoring systems have been developed, making Mt. Etna one of the most intensively studied volcanoes in the world. The measurement of soil CO2 flux for the purpose of identifying a possible correlation between CO2 flux variations and volcanic activity has been carried out for a long time on several active volcanoes around the world. Whilst almost all of these measurements have been made using direct sampling methods in the field, various kinds of automatic devices have more recently been developed to record real-time data, allowing a continuous remote monitoring of volcanic areas. On Mt. Etna the first network of continuous monitoring of geochemical parameters was developed in 2002 by the Istituto Nazionale di Geofisica e Vulcanologia (INGV) of Palermo to monitor CO2 flux from the soil (EtnaGAS network) and was installed at various sites (18 in total) on the flanks of Mt. Etna. The very large quantity of soil CO2 flux data recorded by the network, during which several interesting eruptive phenomena took place, has provided the possibility to make an extensive statistical analysis, the outcome of which strongly suggests that anomalous measurements of CO2 flux was attributable to a volcanic origin and, in almost all cases, preceded the onset of volcanic activity. Here we present an interpretative model of the expected behaviour of CO2 flux from the soil (in terms of cycles of increase-decrease) during and between eruptions, and the actual data-series recorded by EtnaGAS which we found corresponded well with our model. A comparative multidisciplinary approach, incorporating both volcanological and geophysical data puts the global soil CO2 flux trends into a coherent framework that further highlights how the time flux variations are closely related to volcanic activities. This insight into CO2 flux variations, based upon approximately 10 years of uninterrupted data, permit us to conclude that the continuous monitoring of volcanic soil degassing may facilitate the forecasting of imminent eruptive activity or the temporal evolution of an in-progress eruption and, therefore, play an important contributory role in the planning of Civil Defence actions in volcanic areas under high-hazard conditions.

  4. How will the two major Midwest crops respond to global climate change? Results from ten years of investigation at SoyFACE

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Soybean Free Air Concentration Enrichment (SoyFACE) facility is an open-air field "laboratory" for investigating the effects of elevated concentrations of CO2 and ozone, higher temperatures and altered soil water availability on field crops. For over a decade, experiments have examined the produ...

  5. Compact Shelving Ten Years Later.

    ERIC Educational Resources Information Center

    Morris, Leslie R.

    1998-01-01

    Discusses experiences at the Niagara University Library with compact shelving. Highlights include citations to other relevant articles; patron use; selection of vendor; reliability; possible problems; and installation considerations, such as floor-load requirements. (LRW)

  6. Ten Years of Net Work

    ERIC Educational Resources Information Center

    Anklam, Patti

    2009-01-01

    Purpose: The purpose of this paper is to provide a perspective on the emergence of social media and their adoption as a critical element in knowledge management strategy. Social media are defined as the collection of software tools and web-based applications that are personalized, that is, that communications identify individuals by name and…

  7. Photovoltaics: The next ten years

    SciTech Connect

    Yerkes, J.W.

    1984-08-01

    By 1984 companies manufacturing photovoltaics had been doing serious business making low cost solar arrays for twelve years. Grid connected systems of megawatt size are operating in California, and more are on the drawing board. At least six companies in the USA have produced thin film cells of over ten percent and more are working in the field. New short term goals for thin film efficiency in the twelve to fifteen percent range promise to challenge the single crystal silicon cell which has dominated the business since 1972. ARCO Solar believes that a new class of ULTRA GENERATORS twenty percent efficient and selling for two dollars per peak watt can be deployed by utilities in the 1990's.

  8. Mortality and morbidity in a pulp and a paper mill in the United States: a ten-year follow-up.

    PubMed Central

    Ferris, B G; Puleo, S; Chen, H Y

    1979-01-01

    Two hundred and seventy-one men seen in 1963, who worked in a pulp and a paper mill, were followed up ten years later, in 1973. Death certificates were obtained for those who died. There did not appear to be any increased mortality in the group, nor was there any increased specific cause of death. A morbidity study of 200 men seen at both times did not show any differences in respiratory symptoms or prevalence of chronic non-specific respiratory disease. Analysis of pulmonary function showed little, if any, difference between groups. Analysis of retired, deceased, and still-working categories did suggest that exposures to Cl2 or SO2 might have a slight adverse effect on pulmonary function. PMID:465376

  9. Advancing the education in molecular diagnostics: the IFCC-Initiative "Clinical Molecular Biology Curriculum" (C-CMBC); a ten-year experience.

    PubMed

    Lianidou, Evi; Ahmad-Nejad, Parviz; Ferreira-Gonzalez, Andrea; Izuhara, Kenji; Cremonesi, Laura; Schroeder, Maria-Eugenia; Richter, Karin; Ferrari, Maurizio; Neumaier, Michael

    2014-09-25

    Molecular techniques are becoming commonplace in the diagnostic laboratory. Their applications influence all major phases of laboratory medicine including predisposition/genetic risk, primary diagnosis, therapy stratification and prognosis. Readily available laboratory hardware and wetware (i.e. consumables and reagents) foster rapid dissemination to countries that are just establishing molecular testing programs. Appropriate skill levels extending beyond the technical procedure are required for analytical and diagnostic proficiency that is mandatory in molecular genetic testing. An international committee (C-CMBC) of the International Federation for Clinical Chemistry (IFCC) was established to disseminate skills in molecular genetic testing in member countries embarking on the respective techniques. We report the ten-year experience with different teaching and workshop formats for beginners in molecular diagnostics.

  10. Idaho National Laboratory Ten-year Site Plan (2012 through 2021) -- DOE-NE's National Nuclear Capability -- Developing and Maintaining the INL Infrastructure

    SciTech Connect

    Cal Ozaki

    2010-06-01

    To meet long-term objectives to transform the Idaho National Laboratory (INL), we are providing an integrated, long-term vision of infrastructure requirements that support research, development and demonstration (RD&D) goals outlined in the DOE strategic plans, including the NE Roadmap and reports such as Facilities for the Future of Nuclear Energy Research: A Twenty-year Outlook. The goal of the INL Ten-year Site Plan (TYSP) is to clearly link RD&D mission goals and INL core capabilities with infrastructure requirements (single and multi-program), establish the 10-year end-state vision for INL complexes, identify and prioritize infrastructure and capability gaps, as well as the most efficient and economic approaches to closing those gaps.

  11. Changes in the first-pass success rate with the GlideScope video laryngoscope and direct laryngoscope: a ten-year observational study in two academic emergency departments

    PubMed Central

    Lee, Joon Ki; Kang, Hyunggu; Choi, Hyuk Joong

    2016-01-01

    Objective The aim of this study was to assess the success rate of the GlideScope video laryngoscope (GVL) and direct laryngoscope (DL) over ten years in two academic emergency departments. Methods We used adult intubation data using DL and GVL collected from airway management registries at two academic emergency departments. We analyzed changes in first-pass success (FPS) rate by device and operator training level. We conducted a multivariate logistic regression analysis to predict the FPS according to time period. Results Over the study period (2006 to 2010, season I; 2013-2015, season II) the DL usage rate dropped from 91.6% to 45.0% while the GVL usage rate increased from 8.4% to 55.4%. The FPS rate using DL also declined from 90.8% in 2007 to 75.5% in 2015. On the other hand, the FPS rate using GVL increased from 87.8% to 95.2%. With DL, all operators’ FPS rate declined by approximately 10% in season II compared to season I. The FPS rate with GVL was significantly higher in the providers of postgraduate year over 3 years (P=0.043). Multivariate logistic regression analysis revealed an adjusted odds ratio for GVL FPS of 0.799 during season I (P=0.274). However, the adjusted odds ratio for GVL FPS was 3.744 during season II (P<0.001). Conclusion We found that the FPS rates of GVL have slightly increased but DL’s FPS rate has significantly decreased during the last ten years. PMID:28168228

  12. Comparing cost and process performance of activated sludge (AS) and biological aerated filters (BAF) over ten years of full sale operation.

    PubMed

    Hansen, R; Thogersen, T; Rogalla, F

    2007-01-01

    In the early 1990s, the Wastewater Treatment Plant (WWTP) of Frederikshavn, Denmark, was extended to meet new requirements for nutrient removal (8 mg/L TN, 1.5 mg TP/L) as well as to increase its average daily flow to 16,500 m(3)/d (4.5 MGD). As the most economical upgrade of the existing activated sludge (AS) plant, a parallel biological aerated filter (BAF) was selected, and started up in 1995. Running two full scale processes in parallel for over ten years on the same wastewater and treatment objectives enabled a direct comparison in relation to operating performance, costs and experience. Common pretreatment consists of screening, an aerated grit and grease removal and three primary settlers with chemical addition. The effluent is then pumped to the two parallel biological treatment stages, AS with recirculation and an upflow BAF with floating media. The wastewater is a mixture of industrial and domestic wastewater, with a dominant discharge of fish processing effluent which can amount to 50% of the flow. The maximum hydraulic load on the pretreatment section as a whole is 1,530 m(3)/h. Approximately 60% of the sewer system is combined with a total of 32 overflow structures. To avoid the direct discharge of combined sewer overflows into the receiving waters, the total hydraulic wet weather capacity of the plant is increased to 4,330 m(3)/h, or 6 times average flow. During rain, some of the raw sewage can be directed through a stormwater bypass to the BAF, which can be modified in its operation to accommodate various treatment needs: either using simultaneous nitrification/denitrification in all filters with recirculation introducing bottom aeration with full nitrification in some filters for storm treatment and/or post-denitrification in one filter. After treatment, the wastewater is discharged to the Baltic Sea through a 500 m outfall. The BAF backwash sludge, approximately 1,900 m(3) per 24 h in dry weather, is redirected to the AS plant. Primary settler

  13. Racial and Ethnic Variation in the Association of Social Integration with Mortality: Ten-year Prospective Population-based US Study.

    PubMed

    Barger, Steven D; Uchino, Bert N

    2017-03-06

    Substantial data link social relationships with mortality but few studies have examined whether these associations are consistent across racial and ethnic groups. The purpose of the present study was to evaluate the presence and form of the social relationship/mortality association in a representative sample of US Black (n = 4,201), non-Hispanic White (n = 20,217) and Hispanic (n = 5,097) groups. In models adjusted for age, sex, chronic disease, socioeconomic status and smoking social integration was inversely related to ten-year survival in all groups. However, among Whites the association was linear and graded whereas among Blacks the association was linear but was statistically significant only for the highest level of social integration (hazard ratio [HR] = 0.66, 95% confidence interval = 0.47-0.94). A threshold pattern was observed among Hispanics, in that lower mortality risk was found for all social integration categories above the lowest level (HRs from 0.58 to 0.52, P's < 0.01) and each of the higher social integration categories were in turn equivalent. Received social support was unrelated to mortality across all groups. Higher social integration is associated with a survival advantage for Blacks and Whites. For Hispanics, moderate and high levels of social integration were equally protective.

  14. [Dermatophytosis due to Trichophyton rubrum. Ten-year period (1996-2006) data collection in a Dermatology Department in Mexico City].

    PubMed

    Hernández-Salazar, Amparo; Carbajal-Pruneda, Patricia; Fernández Martínez, Ramón; Arenas, Roberto

    2007-06-01

    Dermatophytosis is the most common mycosis in the world up to 80% caused by Trichophyton rubrum. The aim of the present study was to describe the clinical characteristics of the dermatophytosis caused by T. rubrum in a dermatological outpatient clinic during a ten years period, from 1996 to 2005. We collected the data from patients with a dermatophytosis from which we have isolated T. rubrum. A total of 776 patients with dermatophytosis caused by T. rubrum were found. A slight predominance of female patients (56.2%) was observed. The most commonly affected age group was those in the third to the fifth decade of life, and house working women (33.5%) were predominant. Onychomycosis was found in 63% of the cases, tinea pedis in 22.7%, tinea corporis in 5.2% and tinea cruris in 2.8%. In onychomycosis, the first toe nail was the most commonly affected (58.9%) and the dystrophic type was seen in 50.7% of them.

  15. The use of MRI to detect occult fractures of the proximal femur: a study of 102 consecutive cases over a ten-year period.

    PubMed

    Sankey, R A; Turner, J; Lee, J; Healy, J; Gibbons, C E R

    2009-08-01

    An MR scan was performed on all patients who presented to our hospital with a clinical diagnosis of a fracture of the proximal femur, but who had no abnormality on plain radiographs. This was a prospective study of 102 consecutive patients over a ten-year period. There were 98 patients who fulfilled our inclusion criteria, of whom 75 were scanned within 48 hours of admission, with an overall mean time between admission and scanning of 2.4 days (0 to 10). A total of 81 patients (83%) had abnormalities detected on MRI; 23 (23%) required operative management. The use of MRI led to the early diagnosis and treatment of occult hip pathology. We recommend that incomplete intertrochanteric fractures are managed non-operatively with protected weight-bearing. The study illustrates the high incidence of fractures which are not apparent on plain radiographs, and shows that MRI is useful when diagnosing other pathology such as malignancy, which may not be apparent on plain films.

  16. Ten years after the crime: Lasting effects of damage from a cruise ship anchor on a coral reef in St. John, U.S. Virgin Islands

    USGS Publications Warehouse

    Rogers, C.S.; Garrison, V.H.

    2001-01-01

    In October 1988, a cruise ship dropped its anchor on a coral reef in Virgin Islands National Park, St. John, creating a distinct scar roughly 128 m long and 3 m wide from a depth of 22 m to a depth of 6 m. The anchor pulverized coral colonies and smashed part of the reef framework. In April 1991, nine permanent quadrats (1 m2) were established inside the scar over a depth range of 9 m to 12.5 m. At that time, average coral cover inside the scar was less than 1%. These quadrats were surveyed again in 1992, 1993, 1994, 1995 and 1998. Recruits of 19 coral species have been observed, with Agaricia agaricites and Porites spp. the most abundant. Quadrats surveyed outside the scar in June 1994 over the same depth range had a higher percent coral cover (mean = 7.4%, SD = 4.5) and greater average size (maximum length) of coral colonies than in quadrats inside the damaged area. Although coral recruits settle into the scar in high densities, live coral cover has not increased significantly in the last 10 yrs, reflecting poor survival and growth of newly settled corals. The relatively planar aspect of the scar may increase the vulnerability of the recruits to abrasion and mortality from shifting sediments. Ten years after the anchor damage occurred, live coral cover in the still-visible scar (mean = 2.6%, SD = 2.7) remains well below the cover found in the adjacent, undamaged reef.

  17. Hepatitis B vaccination and French Society ten years after the suspension of the vaccination campaign: how should we raise infant immunization coverage rates?

    PubMed

    Balinska, Marta A

    2009-11-01

    In 1998, official concerns were first voiced over a possible association between hepatitis B virus (HBV) vaccination and multiple sclerosis (MS). Despite a number of studies that have demonstrated no such association, ten years on the French population's confidence in the vaccine remains shaken and immunization rates of infants have stagnated beneath 30%. With a chronic carriage of the virus estimated at 0.68%, it seems unlikely that France will be able to control the circulation of the virus. This article analyses attitudes towards HBV vaccination based on recent surveys: not only the public but also the vast majority of "vaccinators" (88%) questions the safety of the vaccine. Physicians opposed to vaccinating infants cite the possibility of adverse events occurring later in life and their lack of trust in the health authorities and the pharmaceutical industry. Both the general public and physicians feel more inclined to vaccinate adolescents and adults, even though it was for these age groups (especially the latter) that neurological adverse events were notified. It appears that above all, the usefulness of the vaccine and its safety profile for young children should be explained in understandable language by all those involved in public health, including the media. However, when opting for public health policies on the basis of statistical estimations, the importance of individual cases (e.g. MS in the family) should not be overlooked both for biological and ethical reasons.

  18. Racial and Ethnic Variation in the Association of Social Integration with Mortality: Ten-year Prospective Population-based US Study

    PubMed Central

    Barger, Steven D.; Uchino, Bert N.

    2017-01-01

    Substantial data link social relationships with mortality but few studies have examined whether these associations are consistent across racial and ethnic groups. The purpose of the present study was to evaluate the presence and form of the social relationship/mortality association in a representative sample of US Black (n = 4,201), non-Hispanic White (n = 20,217) and Hispanic (n = 5,097) groups. In models adjusted for age, sex, chronic disease, socioeconomic status and smoking social integration was inversely related to ten-year survival in all groups. However, among Whites the association was linear and graded whereas among Blacks the association was linear but was statistically significant only for the highest level of social integration (hazard ratio [HR] = 0.66, 95% confidence interval = 0.47–0.94). A threshold pattern was observed among Hispanics, in that lower mortality risk was found for all social integration categories above the lowest level (HRs from 0.58 to 0.52, P’s < 0.01) and each of the higher social integration categories were in turn equivalent. Received social support was unrelated to mortality across all groups. Higher social integration is associated with a survival advantage for Blacks and Whites. For Hispanics, moderate and high levels of social integration were equally protective. PMID:28262712

  19. Genetic gradient of a host-parasite pair along a river persisted ten years against physical mobility: Baltic Salmo salar vs. Gyrodactylus salaris.

    PubMed

    Lumme, Jaakko; Anttila, Pasi; Rintamäki, Päivi; Koski, Perttu; Romakkaniemi, Atso

    2016-11-01

    The Atlantic salmon, Salmo salar L., in the Tornio River in the Northern Baltic Sea basin accommodates a monogenean ectoparasite, Gyrodactylus salaris. The aim of the study was to understand the population structure of apparently co-adapted host-parasite system: no parasite-associated mortality has been reported. The parasite burden among salmon juveniles (parr) was monitored along 460km of the river in 2000-2009. Among the parr, 33.0% were infected (nfish=1913). The genetic structure of the parasite population was studied by sequencing an anonymous nuclear DNA marker (ADNAM1, three main genotypes) and mitochondrial CO1 (three clades, six haplotypes). During the ten years, the parasite population was strongly and stably genetically differentiated among up- and downstream nurseries (nADNAM1=411, FST=0.579; nCO1=443, FST=0.534). Infection prevalence among the smolts migrating to sea was higher than in the sedentary parr populations (82.2%, nfish=129). The spatial differentiation observed among the sedentary juveniles was reflected temporally in the smolt run: parasite genotypes dominating the upper part of the river arrived later than downstream dwellers (medians June 4 and June 2) to the trap 7km from the river mouth. The nuclear and mitochondrial markers were in stable disequilibrium which was not relaxed in the contact zone or among the smolts where the parasite clones often met on individual fish. Only five parasite specimens on smolts (nworms=217) were putative recent sexual recombinants. The contribution of extant salmon hatcheries into the infection was negligible. The host salmon population in Tornio River is known to show significant spatial differentiation (FST=0.022). The stable spatial genetic structure of the parasite against the high physical mobility suggested a possibility of local co-adaptation of the host-parasite subpopulations.

  20. Patterns and predictors of sitting time over ten years in a large population-based Canadian sample: Findings from the Canadian Multicentre Osteoporosis Study (CaMos).

    PubMed

    Gebel, Klaus; Pont, Sarah; Ding, Ding; Bauman, Adrian E; Chau, Josephine Y; Berger, Claudie; Prior, Jerilynn C

    2017-03-01

    Our objective was to describe patterns and predictors of sedentary behavior (sitting time) over 10 years among a large Canadian cohort. Data are from the Canadian Multicentre Osteoporosis Study, a prospective study of women and men randomly selected from the general population. Respondents reported socio-demographics, lifestyle behaviors and health outcomes in interviewer-administered questionnaires; weight and height were measured. Baseline data were collected between 1995 and 1997 (n = 9418; participation rate = 42%), and at 5- (n = 7648) and 10-year follow-ups (n = 5567). Total sitting time was summed across domain-specific questions at three time points and dichotomized into "low" (≤ 7 h/day) and "high" (> 7 h/day), based on recent meta-analytic evidence on time sitting and all-cause mortality. Ten-year sitting patterns were classified as "consistently high", "consistently low", "increased", "decreased", and "mixed". Predictors of sedentary behavior patterns were explored using chi-square tests, ANOVA and logistic regression. At baseline (mean age = 62.1 years ± 13.4) average sitting was 6.9 h/day; it was 7.0 at 5- and 10-year follow-ups (p for trend = 0.12). Overall 23% reported consistently high sitting time, 22% consistently low sitting, 14% decreased sitting, 17% increased sitting with 24% mixed patterns. Consistently high sitters were more likely to be men, university educated, full-time employed, obese, and to report consistently low physical activity levels. This is one of the first population-based studies to explore patterns of sedentary behavior (multi-domain sitting) within men and women over years. Risk classification of sitting among many adults changed during follow-up. Thus, studies of sitting and health would benefit from multiple measures of sitting over time.

  1. Rejection of deeply implanted foreign body induced by acupuncture treatment in patient suffering intractable pains lasting ten years following traumatic injury to the left scapular region during a road accident.

    PubMed

    Sternfeld, M; Hod, I

    1986-01-01

    Upper back pains lasting ten years were promptly improved in a 63 year old woman following the rejection of a forgotten foreign glass body, through a scar located over the left scapula, and treated by acupuncture. The patient insisted on having this treatment after unsuccessful prolonged and multi-disciplinary formal medical interventions culminating in preparations for exploratory surgery. The acupuncture directed to the scar induced an inflammatory reaction characterized by a sterile granulomatous reaction which surrounded a large piece of glass, apparently implanted in the soft tissue of the suprascapular area during a severe road accident which occurred ten years previously. The surgical intervention was avoided.

  2. Enquete sur le langage de l'enfant francais: Transcriptions de conversations d'enfants de 10 ans (Investigation of the Language of French Children: Transcriptions of Conversations of Ten-Year-Olds). Document No. 2.

    ERIC Educational Resources Information Center

    Leclercq, Janine, Comp.

    These transcriptions of conversation illustrate linguistic behavior and interests of the average ten-year-old French child. Patterned after a previously transcribed series of conversations of nine-year olds, the 14 dialogues in this collection serve as a linguistic corpus suitable for educational research and textbook development. A graphic code…

  3. Effectiveness of Seasonal Malaria Chemoprevention in Children under Ten Years of Age in Senegal: A Stepped-Wedge Cluster-Randomised Trial

    PubMed Central

    Cissé, Badara; Sokhna, Cheikh; NDiaye, Jean Louis; Gomis, Jules F.; Dial, Yankhoba; Pitt, Catherine; NDiaye, Mouhamed; Cairns, Matthew; Faye, Ernest; NDiaye, Magatte; Tine, Roger; Faye, Sylvain; Faye, Babacar; Sy, Ousmane; Konate, Lansana; Kouevijdin, Ekoue; Flach, Clare; Faye, Ousmane; Trape, Jean-Francois; Sutherland, Colin; Fall, Fatou Ba; Thior, Pape M.; Faye, Oumar K.; Greenwood, Brian; Gaye, Oumar; Milligan, Paul

    2016-01-01

    Background Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine (SP) plus amodiaquine (AQ), given each month during the transmission season, is recommended for children living in areas of the Sahel where malaria transmission is highly seasonal. The recommendation for SMC is currently limited to children under five years of age, but, in many areas of seasonal transmission, the burden in older children may justify extending this age limit. This study was done to determine the effectiveness of SMC in Senegalese children up to ten years of age. Methods and Findings SMC was introduced into three districts over three years in central Senegal using a stepped-wedge cluster-randomised design. A census of the population was undertaken and a surveillance system was established to record all deaths and to record all cases of malaria seen at health facilities. A pharmacovigilance system was put in place to detect adverse drug reactions. Fifty-four health posts were randomised. Nine started implementation of SMC in 2008, 18 in 2009, and a further 18 in 2010, with 9 remaining as controls. In the first year of implementation, SMC was delivered to children aged 3–59 months; the age range was then extended for the latter two years of the study to include children up to 10 years of age. Cluster sample surveys at the end of each transmission season were done to measure coverage of SMC and the prevalence of parasitaemia and anaemia, to monitor molecular markers of drug resistance, and to measure insecticide-treated net (ITN) use. Entomological monitoring and assessment of costs of delivery in each health post and of community attitudes to SMC were also undertaken. About 780,000 treatments were administered over three years. Coverage exceeded 80% each month. Mortality, the primary endpoint, was similar in SMC and control areas (4.6 and 4.5 per 1000 respectively in children under 5 years and 1.3 and 1.2 per 1000 in children 5-9 years of age; the overall mortality rate

  4. A ten-year experience and follow-up of three hundred patients fitted with the Biomet/Lorenz Microfixation TMJ replacement system.

    PubMed

    Leandro, L F Lobo; Ono, H Y; Loureiro, C C de Souza; Marinho, K; Guevara, H A Garcia

    2013-08-01

    The purpose of this paper is to present the postoperative results obtained after full temporomandibular joint (TMJ) reconstruction employing the Biomet/Lorenz Microfixation TMJ replacement system (Jacksonville, FL, USA) in 300 patients (201 unilateral, 99 bilateral). Objective data (maximum inter-incisal opening; MIO) and subjective data (function and speech, diet, and pain) were collected preoperatively and at postoperative evaluations performed over a 10-year period (mean 3.5, standard deviation 2.1 years). The MIO measures were obtained using a calliper rule. Subjective data were evaluated using a visual analogue scale with scores ranging from 0 to 5 for each variable. The results were analyzed with the paired t-test (two-sided, α=5%). Each patient showed significant improvements for all of the variables at evaluation on postoperative day 7. The results for MIO, function and speech, and diet, showed improvements at each postoperative evaluation over a maximum of 3 years, with stabilization of the results from the fourth year. Complaints of pain decreased considerably up to the 1-month postoperative evaluation, and no patient reported severe pain at 6 months after surgery. The results presented show that the reconstruction of the TMJ through the installation of the Biomet/Lorenz system prosthesis is a safe and effective option for proper reestablishment of the joint and stomatognathic system function; significant long-term improvements in mandibular range of motion are promoted and pain levels decrease.

  5. Low-friction arthroplasty of the hip using alumina ceramic and cross-linked polyethylene. A ten-year follow-up report.

    PubMed

    Wroblewski, B M; Siney, P D; Fleming, P A

    1999-01-01

    We report the results of our continued review of 14 hip arthroplasties using alumina ceramic femoral heads with cross-linked polyethylene cups. There have been no complications and a very low rate of penetration. This was 0.02 mm per year after an initial 'bedding-in' period of two years. There has been no change in the mean rate between our earlier study at six years and the current results at 10 to 11 years. The use of these bearing surfaces appears to reduce the potential amount of polyethylene debris and may provide the next logical stage in the development of the Charnley low-friction arthroplasty.

  6. The sounding rocket as pedagogical tool: a report from ten years of experience with the S.P.I.R.T. undergraduate sounding rocket program

    NASA Astrophysics Data System (ADS)

    Wheeler, Timothy F.

    2005-08-01

    The Student Projects Involving Rocket Investigation Techniques (SPIRIT) program is a long-term, experimential learning, project-based program for undergraduates at Penn State University. Students in 5 functional teams design and build the experiments, but also the structure and rocket systems of a scientific payload. The payloads that emerge from three years of student work show extraordinary creativity. The scientific results, however, have been uneven. This suggests that the highest value of the program is in its educational impact and in the opportunity it provides for development of sounding rocket instruments and research techniques. In this paper, we review the goals and the results of the program from a teaching perspective. We report the results of past and ongoing assessments and present conclusions as to the value and limitations of the program. The SPIRIT program has been popular with students and the university administration. It is relatively inexpensive to run. The willingness of NASA Wallops Island personnel to mentor young students has been critical to the educational success of the program.

  7. Does involvement in food preparation track from adolescence to young adulthood and is it associated with better dietary quality? Findings from a ten-year longitudinal study

    PubMed Central

    Larson, Nicole I.; Neumark-Sztainer, Dianne; Story, Mary

    2012-01-01

    Objectives To examine whether involvement in food preparation tracks over time, between adolescence (15–18 years), emerging adulthood (19–23 years), and the mid-to-late twenties (24–28 years), as well as examine 10-year longitudinal associations between home food preparation, dietary quality and meal patterning. Design Population-based, longitudinal cohort study. Setting Participants were originally sampled from Minnesota public secondary schools (USA). Subjects Participants enrolled in Project EAT (Eating Among Teens)-I, EAT-II, and EAT-III (n=1,321). Results Most participants in their mid-to-late twenties reported an enjoyment of cooking (73% of males, 80% of females); however, few prepared meals including vegetables most days of the week (24% males, 41% females). Participants in their mid-to-late twenties who enjoyed cooking were more likely to have engaged in food preparation as adolescents and emerging adults (p<0.01); those who frequently prepared meals including vegetables were more likely to have engaged in food preparation as emerging adults (p<0.001), but not adolescents. Emerging adult food preparation predicted better dietary quality five years later in the mid-to-late twenties, including higher intakes of fruit, vegetables, dark green/orange vegetables, and less sugar sweetened beverage and fast food consumption. Associations between adolescent food preparation and later dietary quality yielded few significant results. Conclusions Food preparation behaviors appeared to track over time, and engagement in food preparation during emerging adulthood, but not adolescence, was associated with healthier dietary intake during the mid-to-late twenties. Intervention studies are needed to understand whether promoting healthy food preparation results in improvements in eating patterns during the transition to adulthood. PMID:22124458

  8. Integrating toxicity testing in the wastewater management of chemical storage terminals--a proposal based on a ten-year study.

    PubMed

    Rodrigues, Eleni Stark; Umbuzeiro, Gisela de Aragão

    2011-02-28

    Wastewater control at storage terminals of liquid chemical products in bulk is very difficult because of the variety of products handled in the facilities generating effluents of variable composition. The main objective of this work was to verify if the Vibrio fischeri acute toxicity test could be routinely included in the wastewater management of those facilities along with physical and chemical analysis in order to evaluate and improve the quality of the generated effluents. The study was performed in two phases before and after the implementation of better operational practices/treatment technologies. Chemical oxygen demand (COD) and toxicity of treated effluents did not correlate showing that effluents with low COD contain toxic substances and non-biodegradable organic matter, which may be not degraded when discharged into the aquatic environment. Segregation of influents or pre-treatment based on toxicity results and biodegradability index were implemented in the facilities generating significant improvements in the quality of final effluents with reduction of Biochemical oxygen demand (BOD) and toxicity. The integration of physical and chemical analysis with the V. fischeri toxicity test turned out to be an excellent tool for wastewater management in chemical terminals allowing rapid decision making for pollution control and prevention measures. Reuse of rain water was also proposed and when implemented by the facilities resulted in economical and environmental benefits.

  9. Antibiotic-Resistant Bacteria Are Major Threats of Otitis Media in Wollo Area, Northeastern Ethiopia: A Ten-Year Retrospective Analysis

    PubMed Central

    Argaw-Denboba, Ayele; Abejew, Asrat Agalu; Mekonnen, Alemayehu Gashaw

    2016-01-01

    Antibiotic resistance is an increasingly serious threat to human health that needs an urgent action. The aim of this study was to determine the prevalence and antibiotic susceptibility profiles of bacteria isolated from patient ear discharges suspected of otitis media. A retrospective analysis was performed using culture and antibiotic susceptibility test results of 1225 patients who visited Dessie Regional Health Research Laboratory from 2001 to 2011. Results showed a strong association (P < 0.001) between age and the risk of acquiring middle ear infection. The predominant bacterial isolates were Proteus spp. (28.8%), Staphylococcus aureus (23.7%), and Pseudomonas spp. (17.2%). Most of the isolated bacteria showed high resistance to ampicillin (88.5%), ceftriaxone (84.5%), amoxicillin (81.9%), and tetracycline (74.5%). About 72.5% of Proteus spp. and 62.2% of Pseudomonas spp. have developed resistance to one and more antibiotics used to treat them. This retrospective study also revealed the overall antibiotic resistance rate of bacterial isolates was increased nearly twofold (P = 0.001) over the last decade. Relatively, ciprofloxacin and gentamicin were the most effective antibiotics against all the isolates. In conclusion, antibiotic-resistant bacteria are alarmingly increasing in Wollo area, northeastern Ethiopia, and becoming a major public health problem in the management of patients with middle ear infection. PMID:26904125

  10. Bone bank service in Odense, Denmark. Audit of the first ten years with bone banking at the Department of Orthopaedics, Odense University Hospital.

    PubMed

    Nielsen, H T; Larsen, S; Andersen, M; Ovesen, O

    2001-01-01

    There has been an increase in the demand for allograft bone in recent years. The Odense University Hospital bone bank has been in function since 1990, and this paper outlines our results during the 10 year period 1990-1999. Potential donors were screened by contemporary banking techniques which include a social history, donor serum tests for HIV, hepatitis B and C, and graft microbiology. The bones were stored at -80 degrees C. No type of secondary sterilisation was made. 423 femoral heads were approved and donated to 300 patients,1-6 heads/operation. The allografts have been used mainly to reconstruct defects at revision hip arthroplasty (34%), and for fracture surgery (24%). 7 % of all transplanted patients were reoperated because of infection. In the hip revision group the infection rate was 4 %. There were no cases of disease transmission. During the 10 year period there was a change in the clinical use of the allografts. In the first years the allografts were mainly used for spinal fusion surgery, but today the majority are used in hip revision and fracture surgery. The clinical results correspond to those reported in larger international series.

  11. Ten years of continuous observations of stratospheric ozone depleting gases at Monte Cimone (Italy)--comments on the effectiveness of the Montreal Protocol from a regional perspective.

    PubMed

    Maione, M; Giostra, U; Arduini, J; Furlani, F; Graziosi, F; Lo Vullo, E; Bonasoni, P

    2013-02-15

    Halogenated gases potentially harmful to the stratospheric ozone layer are monitored worldwide in order to assess compliance with the Montreal Protocol requiring a phase out of these compounds on a global scale. We present the results of long term (2002-2011) continuous observation conducted at the Mt. Cimone GAW Global Station located on the highest peak of the Italian Northern Apennines, at the border of two important regions: the Po Valley (and the Alps) to the North and the Mediterranean Basin to the South. Bi-hourly air samples of CFC-12, CFC-11, CFC-114, CFC-115, H-1211, H-1301, methyl chloroform, carbon tetrachloride, HCFC-22, HCFC-142b, HCFC-124 and methyl bromide are collected and analysed using a gas chromatograph-mass spectrometer, providing multi annual time series. In order to appreciate the effectiveness of the Montreal Protocol from a regional perspective, trends and annual growth rates of halogenated species have been calculated after identification of their baseline values. A comparison with results from other international observation programmes is also presented. Our data show that the peak in the atmospheric mixing ratios of four chlorofluorocarbons, two halons and two chlorocarbons has been reached and all these species now show a negative atmospheric trend. Pollution episodes are still occurring for species like halon-1211, methyl chloroform and carbon tetrachloride, indicating fresh emissions from the site domain which could be ascribed both to fugitive un-reported uses of the compounds and/or emissions from banks. For the hydrofluorocarbons changes in the baseline are affected by emissions from fast developing Countries in East Asia. Fresh emissions from the site domain are clearly declining. Methyl bromide, for which the Mediterranean area is an important source region, shows, in a generally decreasing trend, an emission pattern that is not consistent with the phase-out schedule of this compound, with a renewed increase in the last two

  12. Ten Years after the Prestige Oil Spill: Seabird Trophic Ecology as Indicator of Long-Term Effects on the Coastal Marine Ecosystem

    PubMed Central

    Moreno, Rocío; Jover, Lluís; Diez, Carmen; Sardà, Francesc; Sanpera, Carola

    2013-01-01

    Major oil spills can have long-term impacts since oil pollution does not only result in acute mortality of marine organisms, but also affects productivity levels, predator-prey dynamics, and damages habitats that support marine communities. However, despite the conservation implications of oil accidents, the monitoring and assessment of its lasting impacts still remains a difficult and daunting task. Here, we used European shags to evaluate the overall, lasting effects of the Prestige oil spill (2002) on the affected marine ecosystem. Using δ15N and Hg analysis, we trace temporal changes in feeding ecology potentially related to alterations of the food web due to the spill. Using climatic and oceanic data, we also investigate the influence of North Atlantic Oscillation (NAO) index, the sea surface temperature (SST) and the chlorophyll a (Chl a) on the observed changes. Analysis of δ15N and Hg concentrations revealed that after the Prestige oil spill, shag chicks abruptly switched their trophic level from a diet based on a high percentage of demersal-benthic fish to a higher proportion of pelagic/semi-pelagic species. There was no evidence that Chl a, SST and NAO reflected any particular changes or severity in environmental conditions for any year or season that may explain the sudden change observed in trophic level. Thus, this study highlighted an impact on the marine food web for at least three years. Our results provide the best evidence to date of the long-term consequences of the Prestige oil spill. They also show how, regardless of wider oceanographic variability, lasting impacts on predator-prey dynamics can be assessed using biochemical markers. This is particularly useful if larger scale and longer term monitoring of all trophic levels is unfeasible due to limited funding or high ecosystem complexity. PMID:24130877

  13. Ten years after the prestige oil spill: seabird trophic ecology as indicator of long-term effects on the coastal marine ecosystem.

    PubMed

    Moreno, Rocío; Jover, Lluís; Diez, Carmen; Sardà-Palomera, Francesc; Sardà, Francesc; Sanpera, Carola

    2013-01-01

    Major oil spills can have long-term impacts since oil pollution does not only result in acute mortality of marine organisms, but also affects productivity levels, predator-prey dynamics, and damages habitats that support marine communities. However, despite the conservation implications of oil accidents, the monitoring and assessment of its lasting impacts still remains a difficult and daunting task. Here, we used European shags to evaluate the overall, lasting effects of the Prestige oil spill (2002) on the affected marine ecosystem. Using δ ¹⁵N and Hg analysis, we trace temporal changes in feeding ecology potentially related to alterations of the food web due to the spill. Using climatic and oceanic data, we also investigate the influence of North Atlantic Oscillation (NAO) index, the sea surface temperature (SST) and the chlorophyll a (Chl a) on the observed changes. Analysis of δ ¹⁵N and Hg concentrations revealed that after the Prestige oil spill, shag chicks abruptly switched their trophic level from a diet based on a high percentage of demersal-benthic fish to a higher proportion of pelagic/semi-pelagic species. There was no evidence that Chl a, SST and NAO reflected any particular changes or severity in environmental conditions for any year or season that may explain the sudden change observed in trophic level. Thus, this study highlighted an impact on the marine food web for at least three years. Our results provide the best evidence to date of the long-term consequences of the Prestige oil spill. They also show how, regardless of wider oceanographic variability, lasting impacts on predator-prey dynamics can be assessed using biochemical markers. This is particularly useful if larger scale and longer term monitoring of all trophic levels is unfeasible due to limited funding or high ecosystem complexity.

  14. The Australian and New Zealand Haemostasis Registry: ten years of data on off-licence use of recombinant activated factor VII

    PubMed Central

    Zatta, Amanda; McQuilten, Zoe; Kandane-Rathnayake, Rangi; Isbister, James; Dunkley, Scott; McNeil, John; Cameron, Peter; Phillips, Louise

    2015-01-01

    Background Recombinant activated factor VII (rFVIIa) has been widely used as an off-licence pan-haemostatic agent in patients with critical bleeding. However, outside the trauma setting, there is relatively little high quality evidence on the risks and benefits of this agent. The Haemostasis Registry was established to investigate the extent of use, dosing, safety and outcomes of patients after off-licence rFVIIa treatment of critical bleeding. Materials and methods The Registry recruited non-haemophiliac patients treated with rFVIIa from 2000–2009 (inclusive) in Australia and New Zealand. Detailed information was gathered on patients’ demographics, context of bleeding, rFVIIa administration, laboratory results, blood component and other therapies, and outcomes. Outcome measures included subjectively assessed effect of rFVIIa on bleeding (response), adverse events (thromboembolic and other) and 28-day mortality. Results The registry included 3,446 cases in 3,322 patients (median [IQR] age 56 [33–70] years, 65% (n=2,147) male). Clinical indications included cardiac surgery (45%), other surgery (18%), trauma (13%), medical bleeding (6%), liver disease (6%), and obstetric haemorrhage (5%). The median [IQR] dose was 91 [72–103] μg/kg and 77% received a single dose. Reduction or cessation of bleeding was reported in 74% and 28-day survival was 71% but outcomes varied depending on clinical context. pH strongly correlated with outcome measures; 81% of patients with pH <7.1 died. Approximately 11% of patients had thromboembolic adverse events. In multivariate analysis, pH prior to administration and bleeding context were independently associated with reported response to rFVIIa and 28-day mortality. Discussion The Haemostasis Registry is the largest dataset of its kind and provides observational data on the off-licence use of rFVIIa over a 10-year period. It has been an invaluable resource for rigorously tracking adverse events and helping to inform clinical

  15. IFKIS - ten years of experience with the intercantonal early warning and crisis information system as a good-practice example for local capacity building

    NASA Astrophysics Data System (ADS)

    Bründl, M.; Stoffel, L.

    2012-04-01

    As a consequence of the avalanche winter in January/February 1999 in Switzerland the project "intercantonal early warning and crisis information system" (IFKIS) was initialised. The goal of this project was to close the gaps recognised in the event analysis of this one-month avalanche period, which caused 17 fatalities and over 600 million CHF of damage [1,2]. Whereas the system of integral avalanche protection consisting of technical measures, land use planning and protection forests proved to be successful, the most important gaps were found to be in the organisational part. Especially communities who did not have an every-winter-experience had faced problems in managing the extraordinary event. The main deficiencies were less experienced or even missing local avalanche safety services and missing information and communication. The results of the IFKIS project embrace a concept for education courses, a concept for compulsory booklets and a guideline for the daily work in local avalanche safety services, and the information system IFKIS-InfoManager improving the two-way communication between the national avalanche warning service and the local services on the one side and enhancing the communication between local and regional avalanche services (IFKIS-MIS) on the other side [3]. The results of the project IFKIS are implemented in practice since 10 years. Since 2000 every winter two to three courses were conducted at two levels either in German, French and Italian. Since 2000 about thousand participants completed the courses. Feedback from participants and observations made by cantonal authorities and the national avalanche warning centre SLF revealed that these education courses greatly improved the local capacity for dealing with critical avalanche situations. The system of regular avalanches courses at the community level served meanwhile as a good-practice example for comparable courses initialised by the Federal Office for the Environment (FOEN) as a

  16. The Los Angeles Healthy Community Neighborhood Initiative: A Ten Year Experience in Building and Sustaining a Successful Community-Academic Partnership

    PubMed Central

    King, Keyonna M; Morris, D’Ann; Jones, Loretta; Lucas-Wright, Aziza; Jones, Felica; del Pino, Homero E; Porter, Courtney; Vargas, Roberto; Kahn, Katherine; Brown, Arleen F; Norris, Keith C

    2016-01-01

    Background Developing effective Community-Academic Partnerships (CAPs) is challenging, and the steps to build and sustain them have not been well documented. This paper describes efforts to form and sustain the Healthy Community Neighborhood Initiative (HCNI), a CAP to improve health in a low-income community in South Los Angeles. Methods Moderated, semi-structured discussions with HCNI community and academic partners were used to develop a framework for CAP formation. Results We identified two key features, shared values and respect, as critical to the decision to form the HCNI. Five elements were identified as necessary for building and sustaining the HCNI: trust, transparency, equity and fairness, adequate resources and developing protocols to provide structure. We also identified several challenges and barriers and the strategies used in the HCNI to mitigate these challenges. Conclusion We developed a framework to incorporate and reinforce the key elements identified as crucial in building and sustaining a CAP in a low-income community. PMID:27747314

  17. Ten-years of bariatric surgery in Brazil: in-hospital mortality rates for patients assisted by universal health system or a health maintenance organization

    PubMed Central

    KELLES, Silvana Márcia Bruschi; MACHADO, Carla Jorge; BARRETO, Sandhi Maria

    2014-01-01

    Background Bariatric surgery is an option for sustained weight loss for the morbidly obese patient. In Brazil coexists the Unified Health System (SUS) with universal coverage and from which depend 150 million Brazilians and supplemental health security, predominantly private, with 50 million beneficiaries. Aim To compare access, in-hospital mortality, length of stay and costs for patients undergoing bariatric surgery, assisted in one or another system. Methods Data from DATASUS and IBGE were used for SUS patients' and database from one health plan of southeastern Brazil for the health insurance patients. Results Between 2001 and 2010 there were 24,342 and 4,356 surgeries performed in SUS and in the health insurance company, respectively. The coverage rates for surgeries performed in 2010 were 5.3 and 91/100.000 individuals in SUS and health insurance respectively. The rate of in-hospital mortality in SUS, considering the entire country, was 0.55 %, 0.44 % considering SUS Southeast, and 0.30 % for the health insurance. The costs of surgery in the SUS and in the health insurance trend to equalization over the years. Conclusion Despite differences in access and characteristics that may compromise the outcome of bariatric surgery, patients treated at the Southeast SUS had similar rate of in-hospital mortality compared to the health insurance patients. PMID:25626935

  18. Wuchereria bancrofti infection in human and mosquito populations of a Polynesian village ten years after interruption of mass chemoprophylaxis with diethylcarbamazine.

    PubMed

    Cartel, J L; Nguyen, N L; Spiegel, A; Moulia-Pelat, J P; Plichart, R; Martin, P M; Manuellan, A B; Lardeux, F

    1992-01-01

    In 1991, a study on Wuchereria bancrofti microfilariae (mf) and infection rates was carried out in the human and mosquito populations of a Polynesian village where, 10 years before, the mf prevalence rate was 6.4% and twice-yearly mass treatment with 3 mg/kg of diethylcarbamazine (DEC) was interrupted. Venous blood samples were collected from 575 (97%) individuals aged 15 years or more, of whom 122 (21.4%) were mf positive. The mf carrier prevalence rate was 27.4% in males, significantly higher than that of 14% in females; it increased from 7-12% in the youngest age group (15-19 years) to 40-50% in the oldest (> or = 60 years) for both males and females. 387 mosquito collections were performed and 1748 female Aedes polynesiensis were dissected, of which 1176 were parous. Among the latter, 114 (9.7%) were infected with Wuchereria bancrofti larvae at L1, L2 or L3 stages. The mean number of larvae per mosquito was 2.46 (range 1-15). Of the 114 infected mosquitoes, 30 harboured L3 larvae, giving a 2.55% infective rate; the mean number of L3 larvae per mosquito was 1.15 (range 1-2). Such findings indicate that the interruption of systematic twice-yearly mass treatment with DEC (3 mg/kg) has resulted, after 10 years, in a substantial increase of microfilarial prevalence in humans, and in high infection rates in mosquitoes.

  19. Change in Antimicrobial Susceptibility of Skin-Colonizing Staphylococcus aureus in Korean Patients with Atopic Dermatitis during Ten-Year Period

    PubMed Central

    Park, Jung-Min; Jo, Ju-Hyun; Jin, Hyunju; Ko, Hyun-Chang; Kim, Moon-Bum; Kim, Jung-Min; Kim, Do-Won; Jang, Ho-Sun

    2016-01-01

    Background A small subset of adolescents atopic dermatitis (AD) tends to persist. This also leads to get more antibiotics exposure with advancing years. Antibiotic resistance has been regarded as a serious problem during Staphylococcus aureus treatment, especially methicillin-resistant S. aureus (MRSA). Objective It was investigated the S. aureus colonization frequency in the skin lesions and anterior nares of adolescent AD patients and evaluated the changes in S. aureus antimicrobial susceptibility for years. Methods Patients who visited our clinic from September 2003 to August 2005 were classified into group A, and patients who visited from August 2010 to March 2012 were classified into group B. To investigate the differences with regard to patients' age and disease duration, the patients were subdivided into groups according to age. Lesional and nasal specimens were examined. Results Among the 295 AD patients, the total S. aureus colonization rate in skin lesions was 66.9% (95/142) for group A and 78.4% (120/153) for group B. No significant changes in the systemic antimicrobial susceptibilities of S. aureus strains isolated from adolescent AD patients were observed during about 10-year period. The increased trend of MRSA isolation in recent adolescent AD outpatients suggest that the community including school could be the source of S. aureus antibiotic resistance and higher fusidic acid resistance rates provides evidence of imprudent topical use. Conclusion Relatively high MRSA isolation and fusidic acid resistance rates in recent AD patients suggest that the community harbors antibiotic-resistant S. aureus. PMID:27489430

  20. Value of pelvic suction-irrigation in reducing morbidity of low anterior resection of the rectum--a ten-year experience.

    PubMed

    Gingold, B S; Jagelman, D G

    1982-04-01

    Resection of the rectosigmoid colon with anastomosis below the peritoneal reflection carries appreciable mortality and morbidity rates particularly because of leakage and resulting sepsis, Protecting the anastomosis with a transverse colostomy does not prevent this complication although it does reduce the catastrophic sequelae that often occur. Anastomotic leakage rates have been reported to be as high as 69% and fecal fistula rates as high as 27% following this type of surgery. A pelvic. A pelvic hematoma may act as a culture medium should sepsis occur and may interfere with anastomotic healing. A method of removing accumulated blood and serum from the pelvis following low anterior resection has been employed with the aim of reducing anastomotic leakage, and a 10-year experience has been compiled. Sixty consecutive patients were studied from July 1970 to June 1980. All underwent barium enema examination and/or proctosigmoidoscopy following low anterior resection with concomitant or previous transverse colostomy. There were four subclinical leaks seen at 6 weeks for an incidence of 6.8%. All resolved spontaneously within 6 additional weeks. No fecal fistulas or pelvic abscesses were encountered. Contaminated blood and serum are significant contributing factors to low anterior anastomotic breakdown. By removing such material before it can become infected, this complication can be significantly reduced.

  1. Scientific publications from mainland China, Taiwan, and Hong Kong in integrative and complementary medicine journals: a ten-year literature survey.

    PubMed

    Li, Xiao-Qian; Tao, Kun-Ming; Zhou, Qing-Hui; Ling, Chang-Quan

    2011-01-01

    Practitioners and researchers from China, the largest user of complementary and alternative medicine (CAM), have been publishing an increasing number of scientific articles in world-famous CAM journals in recent years. However, the status of CAM research in the three major regions of China, the Mainland, Taiwan and Hong Kong has, until now, not been reported. In this study, we compared articles from these three regions published in international CAM journals from 2000 to 2009 using PubMed database and the Journal Citation Reports. The study results showed that the number of published articles from Mainland China increased significantly from 2000 to 2009, particularly since 2005. Meanwhile, the number of published articles from Taiwan also increased, whereas those from Hong Kong remained steady. Clinical trials and randomized controlled trials from Chinese authors both took a small percentage of the total. The impact factors of the journals in which these articles were published suggested similar academic levels whereas the average number of citation of articles from the Mainland was less than those from the other two regions. Journal of Ethnopharmacology, American Journal of Chinese Medicine, Journal of Alternative and Complementary Medicine and Evidence-based Complementary and Alternative Medicine were the most popular journals for Chinese authors.

  2. Ten-year trends in urinary concentrations of triclosan and benzophenone-3 in the general U.S. population from 2003 to 2012.

    PubMed

    Han, Changwoo; Lim, Youn-Hee; Hong, Yun-Chul

    2016-01-01

    Despite their popular use and emerging evidences of adverse health effects, consequent trends in population level triclosan and benzophenone-3 exposure have been poorly evaluated. Therefore, we examined temporal trends of urinary triclosan and benzophenone-3 concentration in the general U.S. population by combining five cycles of National Health and Nutritional Examination Survey (NHANES, 2003-2012) data. We calculated percent changes and the least square geometric means (LSGMs) of urinary triclosan and benzophenone-3 concentration from 10,232 participants by using multivariable regression models. As a result, LSGM concentration of urinary triclosan and benzophenone-3 did not show statistically significant changes over the study period. [Percent change (95% CI): Triclosan, -7.35% (-20.86, 8.47); Benzophenone-3, 7.08% (-27.88, 58.99)] However, we found decreasing trend of urinary triclosan concentration and increasing trend of urinary benzophenone-3 concentration since 2005-2006. Socio-demographic factors which affected urinary concentration of triclosan and benzophenone-3 persisted throughout 10 year study period. Highest income group showed higher level of urinary triclosan and benzophenone-3 concentration. Overall concentration of benzophenone-3 was higher in female than in male, and higher in non-Hispanic Whites than any other races/ethnicities.

  3. Association of dietary fat and carbohydrate consumption and predicted ten-year risk for developing coronary heart disease in a general Japanese population.

    PubMed

    Minoura, Akira; Wang, Da-Hong; Sato, Yoshie; Zou, Yu; Sakano, Noriko; Kubo, Masayuki; Takemoto, Kei; Masatomi, Chie; Ogino, Keiki

    2014-01-01

    We examined the relationships between dietary carbohydrate, protein, fat, and the ratio of n6/n3 fatty acid intakes with the predicted 10-year coronary heart disease (CHD) risk in a general Japanese population. We used the Framingham risk score to determine the 10-year CHD risk of the subjects, who were employees of 6 companies in a single prefecture in Japan. After excluding the subjects who reported any history of angina pectoris, myocardial infarction, diabetes, or cancer, and those with missing data resulting in the inability of estimation of 10-year CHD risk and food intakes, the final data analysis was carried out for 809 subjects. The logistic regression models revealed a significantly increased odds ratio of 10-year CHD risk in the subjects with the highest tertile of carbohydrate intake (% energy) (odds ratio 3.64, 95% CI, 2.07-6.40); after adjustment for other variables, the odds ratio for the 10-year CHD risk was also higher in the subjects with the highest tertile of carbohydrate intake (odds ratio 1.72, 95% CI, 0.70-4.25). We also found that fat intake and the ratio of n6/n3 fatty acids were inversely associated with the predicted 10-year CHD risk (p for trend<0.01). The present findings added evidence of a positive association of dietary carbohydrate and inverse associations of total fat and n6/n3 fatty acid ratio with the predicted 10-year CHD risk in a general Japanese population.

  4. Chelonid herpesvirus 5 in secretions and tumor tissues from green turtles (Chelonia mydas) from Southeastern Brazil: A ten-year study.

    PubMed

    Monezi, Telma A; Mehnert, Dolores U; de Moura, Elisabeth M M; Müller, Natascha M G; Garrafa, Patrícia; Matushima, Eliana R; Werneck, Max R; Borella, Maria I

    2016-04-15

    Fibropapillomatosis (FP), a neoplastic disease characterized by the formation of multiple tumors affecting different species of sea turtles and, most often, the green turtle (Chelonia mydas), is considered one of the major threats to the survival of this species. Recent studies indicate that Chelonid herpesvirus (ChHV5) is the etiological agent of this disease, though its association with anthropogenically altered environments and the immune status of these animals also appears to contribute to disease expression and tumor formation. In this study, tumor biopsy and secretions from green turtles captured off the coast of São Paulo State, Brazil, were used in histological and molecular analyses to detect and characterize circulating ChHV5. In 40.9% of cases, the tumor histopathological findings revealed focal ballooning degeneration with intranuclear inclusion bodies, results which are suggestive of viral infection. ChHV5 was detected using polymerase chain reaction (PCR) on the animals' skin, ocular tumor biopsies, and ocular and oral secretions. The analysis of the detected ChHV5 sequences revealed two distinct genetic sequences together. Phylogenetic analysis indicated that Brazilian samples were similar to ChHV5 samples described for the Atlantic phylogeographic group and are therefore part of the same clade as the Gulf of Guinea and Puerto Rico samples. This similarity suggests a possible flow of the virus between these three regions.

  5. Over Ten Years of Experience with a Modified Right Atrial Anastomosis in Orthotopic Heart Transplantation: Follow-up and Comparison with the Biatrial and Bicaval Technique.

    PubMed

    Huenges, Katharina; Panholzer, Bernd; Fritzsche, Katharina; Broch, Ole; Renner, Jochen; Friedrich, Christine; Rahimi-Barfeh, Azizolah; Reinecke, Alexander; Cremer, Jochen; Haneya, Assad

    2016-07-05

    Background In 1997, a modified right atrial anastomosis (cavoatrial technique) for orthotopic heart transplantation (oHTx) was first developed in our institution. The purpose of this study is to report our long-term experience with this technique compared with biatrial and bicaval technique. Methods Retrospectively, 202 consecutive oHTx between 1997 and 2013 were analyzed. The applied transplantation techniques were biatrial (n = 108), bicaval (n = 22), and cavoatrial (n = 72). Results Demographic data were similar in all groups. The cardiopulmonary bypass and cross-clamp time were significantly shorter in the biatrial group. Follow-up echocardiographic examination showed excellent results in all groups with no relevant differences. After 1 year, occurrence of severe tricuspid regurgitation (biatrial 1.9% vs bicaval 0.0% vs cavoatrial 1.4%) was low in all groups. Rate of permanent pacemaker implantations was also low (12.0% vs 5.0% vs 11.1%). There were no significant differences in survival between the groups. Conclusion The cavoatrial technique can be a safe and simple alternative for heart transplantation. Easy handling and similar reduced postoperative complications encourage the use of this technique.

  6. Alterations in bottom sediment physical and chemical characteristics at the Terra Nova offshore oil development over ten years of drilling on the grand banks of Newfoundland, Canada

    NASA Astrophysics Data System (ADS)

    DeBlois, Elisabeth M.; Paine, Michael D.; Kilgour, Bruce W.; Tracy, Ellen; Crowley, Roger D.; Williams, Urban P.; Janes, G. Gregory

    2014-12-01

    This paper describes sediment composition at the Terra Nova offshore oil development. The Terra Nova Field is located on the Grand Banks approximately 350 km southeast of Newfoundland, Canada, at an approximate water depth of 100 m. Surface sediment samples (upper 3 cm) were collected for chemical and particle size analyses at the site pre-development (1997) and in 2000-2002, 2004, 2006, 2008 and 2010. Approximately 50 stations have been sampled in each program year, with stations extending from less than 1 km to a maximum of 20 km from source (drill centres) along five gradients, extending to the southeast, southwest, northeast, northwest and east of Terra Nova. Results show that Terra Nova sediments were contaminated with >C10-C21 hydrocarbons and barium-the two main constituents of synthetic-based drilling muds used at the site. Highest levels of contamination occurred within 1 to 2 km from source, consistent with predictions from drill cuttings dispersion modelling. The strength of distance gradients for >C10-C21 hydrocarbons and barium, and overall levels, generally increased as drilling progressed but decreased from 2006 to 2010, coincident with a reduction in drilling. As seen at other offshore oil development sites, metals other than barium, sulphur and sulphide levels were elevated and sediment fines content was higher in the immediate vicinity (less than 0.5 km) of drill centres in some sampling years; but there was no strong evidence of project-related alterations of these variables. Overall, sediment contamination at Terra Nova was spatially limited and only the two major constituents of synthetic-based drilling muds used at the site, >C10-C21 hydrocarbons and barium, showed clear evidence of project-related alternations.

  7. Why is seed production so variable among individuals? A ten-year study with oaks reveals the importance of soil environment.

    PubMed

    Pérez-Ramos, Ignacio M; Aponte, Cristina; García, Luis V; Padilla-Díaz, Carmen M; Marañón, Teodoro

    2014-01-01

    Mast-seeding species exhibit not only a large inter-annual variability in seed production but also considerable variability among individuals within the same year. However, very little is known about the causes and consequences for population dynamics of this potentially large between-individual variability. Here, we quantified seed production over ten consecutive years in two Mediterranean oak species - the deciduous Quercus canariensis and the evergreen Q. suber - that coexist in forests of southern Spain. First, we calibrated likelihood models to identify which abiotic and biotic variables best explain the magnitude (hereafter seed productivity) and temporal variation of seed production at the individual level (hereafter CVi), and infer whether reproductive effort results from the available soil resources for the plant or is primarily determined by selectively favoured strategies. Second, we explored the contribution of between-individual variability in seed production as a potential mechanism of satiation for predispersal seed predators. We found that Q. canariensis trees inhabiting moister and more fertile soils were more productive than those growing in more resource-limited sites. Regarding temporal variation, individuals of the two studied oak species inhabiting these resource-rich environments also exhibited larger values of CVi. Interestingly, we detected a satiating effect on granivorous insects at the tree level in Q. suber, which was evident in those years where between-individual variability in acorn production was higher. These findings suggest that individual seed production (both in terms of seed productivity and inter-annual variability) is strongly dependent on soil resource heterogeneity (at least for one of the two studied oak species) with potential repercussions for recruitment and population dynamics. However, other external factors (such as soil heterogeneity in pathogen abundance) or certain inherent characteristics of the tree might be

  8. Suicide attempts and related factors in patients admitted to a general hospital: a ten-year cross-sectional study (1997-2007)

    PubMed Central

    2011-01-01

    Background Suicide and suicide attempts represent a severe problem for public health services. The aim of this study is to determine the socio-demographic and psychopathological variables associated with suicide attempts in the population admitted to a General Hospital. Methods An observational-descriptive study of patients admitted to the A Coruña University Hospital (Spain) during the period 1997-2007, assessed by the Consultation and Liaison Psychiatric Unit. We include n = 5,234 admissions from 4,509 patients. Among these admissions, n = 361 (6.9%) were subsequent to a suicide attempt. Admissions arising from a suicide attempt were compared with admissions occurring due to other reasons. Multivariate generalised estimating equation logistic regression models were used to examine factors associated with suicide attempts. Results Adjusting by age, gender, educational level, cohabitation status, being employed or unemployed, the psychiatric diagnosis at the time of the interview and the information on previous suicide attempts, we found that the variables associated with the risk of a suicide attempt were: age, psychiatric diagnosis and previous suicide attempts. The risk of suicide attempts decreases with age (OR = 0.969). Psychiatric diagnosis was associated with a higher risk of suicide attempts, with the highest risk being found for Mood or Affective Disorders (OR = 7.49), followed by Personality Disorders (OR = 7.31), and Schizophrenia and Other Psychotic Disorders (OR = 5.03). The strongest single predictive factor for suicide attempts was a prior history of attempts (OR = 23.63). Conclusions Age, psychopathological diagnosis and previous suicide attempts are determinants of suicide attempts. PMID:21453478

  9. Evolution in the Management of Acute Myocardial Infarction in the Autonomous Community of Valencia (Spain): Ten Years of the Primvac Registry (1995-2004)

    PubMed Central

    Cabadés, Adolfo; Valencia, José; Rueda, Joaquín; Echánove, Ildefonso; Sanjuán, Rafael; Cebrián, Javier; González-Hernández, Enrique; Cardona, Juan; Colomina, Francisco; Francés, Mercedes; Ortolá, Victoria; Sogorb, Francisco

    2010-01-01

    Introduction and objectives: Several registries of acute myocardial infarction (AMI) have been carried out in Spain, but few remain active. This work analyses the evolution of the characteristics and control of patients with AMI during the first 10 years of the PRIMVAC registry, initiated in 1995. Methods: The demographical and clinical characteristics, therapeutic-diagnostic procedures and pharmacological treatment of patients admitted with AMI between January 1995 and December 2004, were analysed in 17 coronary centres in the Autonomous Community of Valencia (South eastern Spain). Results: The mean age of the 19,719 patients recruited was of 65. The percentage of women, hypertension, hypercholestrolemia and diabetes increased during registry period. The median time of symptoms onset-hospital arrival was 151 minutes, without a decrease over the time, and the delay of thrombolysis fell from 200 to 154 minutes (p<0.01). Percentage of thrombolytic treatment oscillated between 39% and 48%. The mortality in the coronary units decreased (14.1% vs. 8.9%; p<0.001). The number of coronary angiography and percutaneous revascularisation performed increased up to 61% and 32%, respectively, of patients included. On discharge, the use of beta-blockers (29.3% vs. 66.7%), angiotensin-converting enzyme (ACE) inhibitors (41.7% vs. 57.9%) and statins (29.3% vs. 71%) went up. Conclusions: Overall mortality in the coronary unit decreased, without any variation in the incidence of serious complications. Time to thrombolysis was reduced over the time, with no significant increment in its use. The performance of coronary angiography and percutaneous revascularisation increased, with a low use of primary angioplasty. The use of beta-blockers, ACE inhibitors and statins increased at discharge. PMID:23675181

  10. Ten-year study of fine aerosol at Sde Boker, Israel, using PIXE: Time trends, seasonal variation, correlations, and source areas for anthropogenic elements

    NASA Astrophysics Data System (ADS)

    Maenhaut, Willy; Karnieli, Arnon; Andreae, Meinrat O.

    2014-01-01

    From January 1995 through December 2004 aerosol samples were collected at Sde Boker, Israel, with a Gent stacked filter unit sampler. The collections were done according to a 2-2-3 day schedule, which resulted in about 150 samples per year. The samples were analysed for the particulate mass (PM) by weighing, for black carbon (BC) by a light reflectance technique, and for up to 46 elements by a combination of PIXE and instrumental neutron activation analysis. Here, we report on the fine (PM2) size fraction data for the PM, BC, and the following nine anthropogenic elements S, V, Ni, Cu, Zn, As, Se, Sb, and Pb, and discuss their time trends, seasonal variation, correlations, and source areas. The largest changes in the annual medians over the 10-year period were found for S, Ni, Se, Sb, and Pb, i.e., of -34%, -25%, -47%, +26%, and -40%, respectively. The seasonal variation was largest for S, with 1.6 times higher concentrations in summer than in the other three seasons. Vanadium and Ni were very highly correlated with each other (r = 0.95), pointing to a dominant common source, which is undoubtedly oil burning. Trajectory statistics, using 10-day back trajectories with arrival at 300 m above ground, were applied to assess the source areas. Sulphur originated mostly from south-eastern Europe (i.e., Turkey, Bulgaria, Romania, Ukraine, and southern Russia) and As from the south-eastern part of European Russia, whilst the source picture for Zn was rather unclear. The other six anthropogenic elements and BC seemed to originate mainly from regional sources.

  11. Seasonal and inter-annual eutrophication dynamics in a hypereutrophic shallow coastal lagoon from ten years of satellite observations and in-situ data

    NASA Astrophysics Data System (ADS)

    Pitarch, Jaime; Ruiz-Verdú, Antonio; Soria, Juan M.; Santoleri, Rosalia

    2016-04-01

    The Albufera de Valencia (39.33 N, 0.37 W) is a hypereutrophic shallow coastal lagoon, having a near round shape of ~ 5 km diameter and ~ 1 m average depth. At the west side, the lake is separated from the sea by a narrow land strip, but three artificial channels allow connection to the sea, regulated by gates. The rest of the lake is surrounded by rice fields that were made by gaining surface from the lake around a century ago. Nowadays, the ecological state of the lake is very degraded. Freshwater inflow is insufficient and residence time is too high. Despite some improvements in waste water treatment, high loads of sediment-stored nutrients are often resuspended due to habitual strong winds and made available for primary production. The previously abundant bottom vegetation disappeared decades ago and secchi depth does not reach more than few tens of centimeters. The lake suffers from cyanobacterial blooms and massive fish deaths. Despite its vital importance as a coastal wetland in the western Mediterranean region, its water quality is not routinely monitored, so its seasonality and eventual blooming events have not been sistematically studied. In this study, we aim at filling this gap using satellite data. Medium-resolution satellite-borne sensors constitute an appropriate tool for this sake due to the lake's medium size and little cloud cover time over the region. In particular, the European MERIS sensor (2002-2012) is specially well suited due to its unique spectral bands configuration for cyanobacterial detection. Apart from the utility of the results themselves, study of this sensor provides a strong baseline for operational utilization of its successor, the new-coming European Sentinel 3-OLCI sensor. We have processed the full archived MERIS archived data. By adequate choice of band ratios and posterior calibration to in-situ samples, the time series of chlorophyll concentration is derived. Derived seasonality reveals a pattern that is determined by the

  12. Ten years of global burned area products from spaceborne remote sensing-A review: Analysis of user needs and recommendations for future developments

    NASA Astrophysics Data System (ADS)

    Mouillot, Florent; Schultz, Martin G.; Yue, Chao; Cadule, Patricia; Tansey, Kevin; Ciais, Philippe; Chuvieco, Emilio

    2014-02-01

    Early global estimates of carbon emissions from biomass burning were based on empirical assumptions of fire return interval in different biomes in the 1980s. Since then, significant improvements of spaceborne remote sensing sensors have resulted in an increasing number of derived products characterizing the detection of active fire or the subsequent burned area (GFED, MODIS MCD45A1, L3JRC, Globcarbon, GBS, GLOBSCAR, GBA2000). When coupled with global land cover and vegetation models allowing for spatially explicit fuel biomass estimates, the use of these products helps to yield important information about the spatial and the temporal variability of emission estimates. The availability of multi-year products (>10 years) leads to a better understanding of uncertainties in addition to increasing accuracy. We surveyed a wide range of users of global fire data products whilst also undertaking a review of the latest scientific literature. Two user groups were identified, the first being global climate and vegetation modellers and the second being regional land managers. Based on this review, we present here the current needs covering the range of end-users. We identified the increasing use of BA products since the year 2000 with an increasing use of MODIS as a reference dataset. Scientific topics using these BA products have increased in diversity and area of application, from global fire emissions (for which BA products were initially developed) to regional studies with increasing use for ecosystem management planning. There is a significant need from the atmospheric science community for low spatial resolution (gridded, 1/2 degree cell) and long time series data characterized with supplementary information concerning the accuracy in timing of the fire and reductions of omission/commission errors. There is also a strong need for precisely characterizing the perimeter and contour of the fire scar for better assimilation with land cover maps and fire intensity. Computer

  13. A population-based registry as a source of health indicators for rare diseases: the ten-year experience of the Veneto Region’s rare diseases registry

    PubMed Central

    2014-01-01

    Background Although rare diseases have become a major public health issue, there is a paucity of population-based data on rare diseases. The aim of this epidemiological study was to provide descriptive figures referring to a sizable group of unrelated rare diseases. Methods Data from the rare diseases registry established in the Veneto Region of north-east Italy (population 4,900,000), referring to the years from 2002 to 2012, were analyzed. The registry is based on a web-based system accessed by different users. Cases are enrolled by two different sources: clinicians working at Centers of expertise officially designated to diagnose and care patients with rare diseases and health professionals working in the local health districts. Deaths of patients are monitored by Death Registry. Results So far, 19,547 patients with rare diseases have been registered, and 23% of them are pediatric cases. The overall raw prevalence of the rare diseases monitored in the population under study is 33.09 per 10,000 inhabitants (95% CI 32.56-33.62), whilst the overall incidence is 3.85 per 10,000 inhabitants (95% CI 3.67-4.03). The most commonly-recorded diagnoses belong to the following nosological groups: congenital malformations (Prevalence: 5.45/10,000), hematological diseases (4.83/10,000), ocular disorders (4.47/10,000), diseases of the nervous system (3.51/10,000), and metabolic disorders (2,95/10,000). Most of the deaths in the study population occur among pediatric patients with congenital malformations, and among adult cases with neurological diseases. Rare diseases of the central nervous system carry the highest fatality rate (71.36/1,000). Rare diseases explain 4.2% of general population Years of Life Lost (YLLs), comparing to 1.2% attributable to infectious diseases and 2.6% to diabetes mellitus. Conclusions Our estimates of the burden of rare diseases at population level confirm that these conditions are a relevant public health issue. Our snapshot of their epidemiology

  14. Ten years of marketing approvals of anticancer drugs in Europe: regulatory policy and guidance documents need to find a balance between different pressures

    PubMed Central

    Apolone, G; Joppi, R; Bertele', V; Garattini, S

    2005-01-01

    Despite important progress in understanding the molecular factors underlying the development of cancer and the improvement in response rates with new drugs, long-term survival is still disappointing for most common solid tumours. This might be because very little of the modest gain for patients is the result of the new compounds discovered and marketed recently. An assessment of the regulatory agencies' performance may suggest improvements. The present analysis summarizes and evaluates the type of studies and end points used by the EMEA to approve new anticancer drugs, and discusses the application of current regulations. This report is based on the information available on the EMEA web site. We identified current regulatory requirements for anticancer drugs promulgated by the agency and retrieved them in the relevant directory; information about empirical evidence supporting the approval of drugs for solid cancers through the centralised procedure were retrieved from the European Public Assessment Report (EPAR). We surveyed documents for drug applications and later extensions from January 1995, when EMEA was set up, to December 2004. We identified 14 anticancer drugs for 27 different indications (14 new applications and 13 extensions). Overall, 48 clinical studies were used as the basis for approval; randomised comparative (clinical) trial (RCT) and Response Rate were the study design and end points most frequently adopted (respectively, 25 out of 48 and 30 out of 48). In 13 cases, the EPAR explicitly reported differences between arms in terms of survival: the range was 0–3.7 months, and the mean and median differences were 1.5 and 1.2 months. The majority of studies (13 out of 27, 48%) involved the evaluation of complete and/or partial tumour responses, with regard to the end points supporting the 27 indications. Despite the recommendations of the current EMEA guidance documents, new anticancer agents are still often approved on the basis of small single arm

  15. Ten-Year Outcomes: The Clinical Utility of Single Photon Emission Computed Tomography/Computed Tomography Capromab Pendetide (Prostascint) in a Cohort Diagnosed With Localized Prostate Cancer

    SciTech Connect

    Ellis, Rodney J.; Kaminsky, Deborah A.; Zhou, Esther H.; Fu, Pingfu; Chen, Wei-Dong; Faulhaber, Peter F.; Bodner, Donald

    2011-09-01

    Purpose: To evaluate the clinical utility of capromab pendetide imaging with single photon emission computed tomography coregistration with computed tomography (SPECT/CT) in primary prostate cancer (CaP) for pretreatment prognostic staging and localization of biologic target volumes (BTV) for individualized image-guided radiotherapy dose escalation (IGRT-DE). Methods and Materials: Patients consecutively presenting for primary radiotherapy (February 1997 to December 2002), having a clinical diagnosis of localized CaP, were evaluated for tumor stage using conventional staging and SPECT/CT (N = 239). Distant metastatic uptake (mets) were identified by SPECT/CT in 22 (9.2%). None of the suspected mets could be clinically confirmed. Thus, all subjects were followed without alteration in disease management. The SPECT/CT pelvic images defined BTV for IGRT-DE (+150% brachytherapy dose) without (n = 150) or with (n = 89) external radiation of 45 Gy. The National Comprehensive Cancer Network criteria defined risk groups (RG). The median survivor follow-up was 7 years. Biochemical disease-free survival (bDFS) was reported by clinical nadir +2 ng/mL (CN+2) criteria. Statistical analyses included Kaplan-Meier, multivariate analysis, and Concordance-index models. Results: At 10-year analyses, overall survival was 84.8% and bDFS was 84.6%. With stratification by RG, CN+2 bDFS was 93.5% for the low-RG (n = 116), 78.7% for the intermediate-RG (n = 94), and 68.8% for the high-RG (n = 29), p = 0.0002. With stratification by pretreatment SPECT/CT findings, bDFS was 65.5% in patients with suspected mets (n = 22) vs. 86.6% in patients with only localized uptake (n = 217), p = 0.0014. CaP disease-specific survival (DSS) was 97.7% for the cohort. With stratification by SPECT/CT findings, DSS was 86.4% (with suspected mets) vs. 99.0% (localized only), p = 0.0001. Using multivariate analysis, the DSS hazard ratio for SPECT/CT findings (mets vs. localized) was 3.58 (p = 0.0026). Concordance

  16. Prevalence of SCN1A-Related Dravet Syndrome among Children Reported with Seizures following Vaccination: A Population-Based Ten-Year Cohort Study

    PubMed Central

    Verbeek, Nienke E.; van der Maas, Nicoline A. T.; Jansen, Floor E.; van Kempen, Marjan J. A.; Lindhout, Dick; Brilstra, Eva H.

    2013-01-01

    Objectives To determine the prevalence of Dravet syndrome, an epileptic encephalopathy caused by SCN1A-mutations, often with seizure onset after vaccination, among infants reported with seizures following vaccination. To determine differences in characteristics of reported seizures after vaccination in children with and without SCN1A-related Dravet syndrome. Methods Data were reviewed of 1,269 children with seizures following immunization in the first two years of life, reported to the safety surveillance system of the Dutch national immunization program between 1 January 1997 and 31 December 2006. Selective, prospective follow-up was performed of children with clinical characteristics compatible with a diagnosis of Dravet syndrome. Results In 21.9% (n = 279) of children, a diagnosis of Dravet syndrome could not be excluded based on available clinical data (median age at follow-up 16 months). Additional follow-up data were obtained in 83.9% (n = 234) of these children (median age 8.5 years). 15 (1.2% of 1,269; 95%CI:0.6 to 1.8%) children were diagnosed with SCN1A-related Dravet syndrome. Of all reported seizures following vaccinations in the first year of life, 2.5% (95%CI:1.3 to 3.6%) were due to SCN1A-related Dravet syndrome, as were 5.9% of reported seizures (95%CI:3.1 to 8.7%) after 2nd or 3rd DTP-IPV-Hib vaccination. Seizures in children with SCN1A-related Dravet syndrome occurred more often with a body temperature below 38.5°C (57.9% vs. 32.6%, p = 0.020) and reoccurred more often after following vaccinations (26.7% vs. 4.0%, p = 0.003), than in children without a diagnosis of SCN1A-related Dravet Syndrome. Conclusions Although Dravet syndrome is a rare genetic epilepsy syndrome, 2.5% of reported seizures following vaccinations in the first year of life in our cohort occurred in children with this disorder. Knowledge on the specific characteristics of vaccination-related seizures in this syndrome might promote early diagnosis and indirectly

  17. The NOGAPS Ten Year AMIP Integration

    DTIC Science & Technology

    1993-10-01

    problems with open) c C c character*54 file character*48 fitnmai character*8 status character*6 ctau c logical lex,opn,iread c Lenr = 8*(2.len) if(itype.ne...return endi f c endi f c open(unit~iun,file~file,access=’direct’,form~’unformattedI *, recl= lenr ,status=status) C if(msg.tt.2) return c print 100...status(1:3),fiLnam,iun, Lenr 100 format(lx,a3,lx,a54,1 opened as unit=’,i3,’ : Lenr =’,i9,’ bytes ’) return end subroutine nfread(fnam,msg,itype,istrt,nrec

  18. Ten Years of ODAS in Retrospect

    ERIC Educational Resources Information Center

    Simon, Arthur B.

    1974-01-01

    Reviewed are growth, activities, and changes of the Oral Deaf Adults Section (ODAS) of the Alexander Graham Bell Association since its establishment in 1964 to aid adjustment of the deaf to society. (MC)

  19. Ten Years of Success at Minority Recruitment

    ERIC Educational Resources Information Center

    Turner, B. A.

    1974-01-01

    Summarizes the Minority Manpower Resources Project conducted through the joint efforts of the NASA - Manned Spacecraft Center and Texas Southern University. Indicates that the main reason for the project's success is the identification, careful screening of high quality ethnic minority students. (CC)

  20. Lesbian Health Issues: A Ten Year Review.

    ERIC Educational Resources Information Center

    Ellingson, Lyndall

    2002-01-01

    Reviews research on lesbian health risks and behavior, noting methodological difficulties, and focusing on health risks (alcohol, tobacco, and other drug use and sexually transmitted infections) and health care (early detection behavior and barriers to preventive care). Overall, there are behavioral, perceptual, and experiential differences…

  1. A CAS Project Ten Years On

    ERIC Educational Resources Information Center

    Garner, Sue; Pierce, Robyn

    2016-01-01

    Although research shows that Computer Algebra Systems offer pedagogical opportunities, more than a decade later some teachers are reluctant to change established practices. In 2002, the University of Melbourne in Australia launched a research project to investigate implementation of a senior mathematics course in which students could use a…

  2. Ten Years of the Armenian Virtual Observatory

    NASA Astrophysics Data System (ADS)

    Mickaelian, A. M.; Astsatryan, H. V.; Knyazyan, A. V.; Magakian, T. Yu.; Mikayelyan, G. A.; Erastova, L. K.; Hovhannisyan, L. R.; Sargsyan, L. A.; Sinamyan, P. K.

    2016-06-01

    Armenian Virtual Observatory (ArVO, www.aras.am/Arvo/arvo.htm) was created 10 years ago, in 2005, when after the accomplishment of the Digitized First Byurakan Survey (DFBS, www.aras.am/Dfbs/dfbs.html) we had enough resources to run a VO project and contribute in the International Virtual Observatory Alliance (IVOA, www.ivoa.net). ArVO is a project of Byurakan Astrophysical Observatory (BAO) aimed at construction of a modern system for data archiving, extraction, acquisition, reduction, use and publication. ArVO technical and research projects include Global Spectroscopic Database, which is being built based on DFBS. Quick optical identification of radio, IR or X-ray sources will be possible by plotting their positions in the DFBS or other spectroscopic plate and matching all available data. Accomplishment of new projects by combining data is so important that the International Council of Scientific Unions (ICSU) recently created World Data System (WDS, www.icsu-wds.org/) for unifying data coming from all science areas, and BAO has also joined it due to DFBS and ArVO projects.

  3. The Columbine Tragedy Ten Years Later

    ERIC Educational Resources Information Center

    Hammond, Jane

    2009-01-01

    Some tragedies are so emblazoned in people's minds that years later they can recall where they were when they first heard the news. The assassinations of John F. Kennedy and Martin Luther King Jr., the Challenger explosion, and the Sept. 11 terrorist attacks are among these events. So also is the Columbine High School tragedy of April 20, 1999.…

  4. Hong Kong: Ten Years After the Handover

    DTIC Science & Technology

    2007-06-29

    stockholder of the newspaper, Robert Kuok Hock Nien; and in 2004, the hosts of the radio shows “Smoke Signals” (Fung Yin), “Teacup in a Tempest” (Fung Bor...35 For a description of the pre-Handover Hong Kong economic network, see Hong Hong Advantage, by Michael Enright , Edith Scott, and David Dodwell...Hong Kong & the Pearl River Delta: The Economic Interaction, by Michael J. Enright , Chang Ka Mun, Edith Scott, and Zhu Wen Hui, sponsored by the 2022

  5. Ten years' experience with pediatric gunshot wounds.

    PubMed

    Barlow, B; Niemirska, M; Gandhi, R P

    1982-12-01

    Gunshot wounds in children have become a significant source of morbidity and mortality in our community in the last 10 yr. One hundred eight children, 16 yr of age and younger, were admitted to the Pediatric Surgical Service for gunshot wounds during this period; only 1 child was admitted for a gunshot wound in the 10 yr preceding this review. Rapid resuscitation and triage of major injuries directly to the operating room achieved a 94% survival. Review of the circumstances of injury revealed that 42% of the gunshot wounds were inflicted by children and 40% were known to have been intentional. Only 20% of the patients had known drug involvement; in general this was involvement in drug selling, not in drug abuse. Social service intervention can offer significant benefit to these children, but ultimately gun control laws with strict enforcement are needed to stop this type of violence toward children.

  6. Late stillbirth: a ten year cohort study.

    PubMed

    Robalo, Raquel; Pedroso, Célia; Amaral, Njila; Soares, Clara

    2013-01-01

    Introdução: A morte fetal tardia é um acontecimento que se mantém na prática diária, apesar de protocolos de vigilância pré-natal e intraparto. Objectivo: Análise dos factores que contribuíram para a causa principal ou condições associadas a morte fetal tardia num período de 10 anos Métodos: Coorte retrospectiva de 208 gestações tardias simples, cujo parto em unidade terciária de cuidados perinatais resultou no nascimento de um nado morto, num período de dez anos. Através de consulta de processo clínico foram analisados dados clínicos, laboratoriais e resultados de estudo anatomo-patológico feto-placentário. Resultados: A incidência de morte fetal tardia foi de 3,5 por cada 1000 nascimentos. Não foram encontradas quaisquer tendências na incidência de MF tardia ao longo do tempo de estudo. Em 12 (5,8%) casos a morte fetal foi um acontecimento intraparto e 72 (35%) eram gestações de termo. Em 14% a gravidez não foi vigiada. A IG média de diagnóstico foi 34 semanas. A principal causa de morte associou-se a patologia fetal, tendo sido identificados factores fetais em 59 casos, destes 25% foram considerados leves para a idade gestacional. Em 24.5% dos casos a causa de morte foi inexplicada. Identificaram-se factores de risco materno em 21% dos casos, a patologia hipertensiva foi frequente e foi associada a idade gestacional precoce (p = 0,028). Conclusões: Não houve oscilações na incidência de morte fetal tardia ao longo dos dez anos avaliados. A incidência foi de 3,5‰, idêntica à descrita em países desenvolvidos. Cerca de um quarto das mortes fetais foram inexplicadas. A patologia materna mais frequente foi a hipertensão crónica.

  7. Hyperactive Children: A Ten-Year Study

    ERIC Educational Resources Information Center

    Miller, James S.

    1978-01-01

    Available from: Arthur Retlaw and Associates, Inc., Suite 2080, 1603 Orrington Avenue, Evanston, Illinois 60201. A 10-year pediatric practice involving the observation of 290 children diagnosed as hyperactive led to the beliefs that hyperactivity is an emotional problem and that the child's inner state or family relationships should be central…

  8. The pyroelectric vidicon - Ten years on

    NASA Astrophysics Data System (ADS)

    Burgess, D.; Nixon, R.; Ritchie, J.

    1986-01-01

    A technology development status evaluation is presented for British high performance pyroelectric vidicon, IR-sensitive TV cameras, the first tubes and cameras of which were demonstrated over a decade ago. Attention is given to the improvements that had to be instituted in camera design in order to obtain optimum performance from the vidicon tubes. A rotating disk chopper and flicker processing were incorporated into the camera's design. Pyroelectric cameras have been extensively applied in industry and the police and military services for fire detection and in rescue operations.

  9. The Next Ten Years in Education.

    ERIC Educational Resources Information Center

    Dede, Chris

    A person's beliefs about the future are very powerful in shaping his or her actions. The issue of what image of the next 10 years is most appropriate for educators today can be examined metaphorically with differing visions of what education can become. By using a series of predictions and by consolidating forecasts from futures research,…

  10. Assessment Update: The First Ten Years.

    ERIC Educational Resources Information Center

    National Center for Higher Education Management Systems, Boulder, CO.

    This document provides complete collections of columns from the journal "Assessment Update" for the past 10 years. By-lined columns from Trudy W. Banta, Editor, include articles on: (1) encouraging faculty involvement in assessment; (2) the growing variety of assessment methods; (3) assessment in response to external pressures: performance funding…

  11. Ten-year space launch technology plan

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This document is the response to the National Space Policy Directive-4 (NSPD-4), signed by the President on 10 Jul. 1991. Directive NSPD-4 calls upon the Department of Defense (DoD), the Department of Energy (DOE), and the National Aeronautics and Space Administration (NASA) to coordinate national space launch technology efforts and to jointly prepare a 10-year space launch technology plan. The nation's future in space rests on the strength of its national launch technology program. This plan documents our current launch technology efforts, plans for future initiatives in this arena, and the overarching philosophy that links these activities into an integrated national technology program.

  12. Spacelab - Ten years of international cooperation

    NASA Technical Reports Server (NTRS)

    Bignier, M.; Harrington, J. C.; Sander, M. J.

    1983-01-01

    The history, current status, and future plans of the Spacelab program are reviewed, with a focus on the cooperative relationship between ESA and NASA. The initial decision to undertake the program and the three agreements signed to begin its implementation are examined, and the division of responsibilities and financial contributions is discussed insofar as it affected the management structure. Consideration is given to the major facilities, the 50-mission operational cycle, communications, the currently scheduled activities (through 1985), the prospective later uses, and the ten dedicated discipline laboratories. The importance of continuous mutual support during the planning and development phases is stressed. The program so far is considered a success, in terms of the goals set by the participants and in terms of the resolution of the problems inherent in international technological endeavors.

  13. Overview and In-Orbit Behaviour of the First Lithium-Ion Batteries Used Onboard Eutelsat 7A and Eutelsat Hot Bird 13B GEO Telecommunication Satellite- Update after Ten Years in Orbit

    NASA Astrophysics Data System (ADS)

    Malet, Fabien; Leconte, Vincent; Borthomieu, Yannick; Bauchais, Frederic

    2014-08-01

    The Lithium-ion (Li-ion) battery has been perceived several years ago by Astrium as a very promising technology in terms of technical, industrial and cost aspects for its Eurostar 3000 platform dedicated to telecommunications satellite for payload power from 5 up to 15 kW and for Alphabus Platform from 10 up to 22 kW. One of the main advantages of such energy storage technology is the capacity to deliver very high power and energy density with quite low dissipation when compared to the other qualified technologies. On March 15, 2004, a Proton Launcher placed successfully into orbit the EUTELSAT 7A spacecraft called "W3A" for Eutelsat (first commercial satellite equipped with Li- ion batteries). This was the achievement of the work, initiated with the support of ESA and CNES in 1996 with Stentor program. In 2014, 45 Li-ion batteries are in orbit on 24 Eurostar 3000 satellites and one battery on Alphabus platformThis paper is an update of the one presented at the Nineth European Space Power Conference in 2011 [1]. First part is a recall of the battery development, battery design, and battery management during system tests and pre-launch phases. In the second part, the ten years behaviour in orbit for the two W3A batteries and the seven years behaviour for the two EUTELSAT HOT BIRD 13B called "HB8" batteries is provided.

  14. Yttrium-90 (90Y) in the principal radionuclide therapies: an efficacy correlation between peptide receptor radionuclide therapy, radioimmunotherapy and transarterial radioembolization therapy. Ten years of experience (1999-2009).

    PubMed

    Goffredo, Veronica; Paradiso, Angelo; Ranieri, Girolamo; Gadaleta, Cosmo Damiano

    2011-12-01

    The clinical application of the pure beta emitter (90)Y constitutes a fundamental advancement in non-invasive medicine. Nowadays, mainly three oncological therapies exploit the intrinsic emissive characteristic of (90)Y. Radionuclide therapies include peptide receptor radionuclide therapy (PRRT) in neuroendocrine tumour (NET) treatment, radioimmunotherapy (RIT) in non-Hodgkin's lymphoma (NHL) treatment and transarterial radioembolization therapy (TARET) in unresectable hepatocellular carcinoma (HCC) and liver metastatic colorectal cancer (mCRC) treatment. The last ten years of clinical experience from E-PubMed research have been reviewed and an efficacy correlation between (90)Y-therapies has shown a better objective response rate for RIT (ORR 80±15%; range 53-100) compared to PRRT (ORR 23.5±14%; range 9-50), and TARET (ORR for mCRC, 40±25%; range 19-91, and ORR for HCC, 42±20%; range 20-82). This review reports on the state of the art of the efficacy of (90)Y-therapies from the last decade and discusses new perspectives of therapeutic development.

  15. Deburring and surface finishing: The past ten years and projections for the next ten years

    SciTech Connect

    Gillespie, L.K.

    1990-09-01

    The 1970s were a decade of significant growth in deburring and surface finishing. In the 1980s progress was made in robotic finishing, burr formation models, surface finish measurement, new processes, equipment and tooling. The centers of burr and surface related research changed. The decade of the 1990s will bring greater competition, environmental restrictions, more processes, more automation, and better characterization and simulation of processes.

  16. A ten-year surveillance study of carbapenemase-producing Klebsiella pneumoniae in a tertiary care Greek university hospital: predominance of KPC- over VIM- or NDM-producing isolates.

    PubMed

    Spyropoulou, Aikaterini; Papadimitriou-Olivgeris, Matthaios; Bartzavali, Christina; Vamvakopoulou, Sophia; Marangos, Markos; Spiliopoulou, Iris; Anastassiou, Evangelos D; Christofidou, Myrto

    2016-03-01

    Resistance patterns and carbapenemase gene presence among Klebsiella pneumoniae isolates from the University General Hospital of Patras, Greece during a ten-year period were analysed under a surveillance programme for multi-drug-resistant bacteria. From 2005 to 2014, K. pneumoniae isolates from clinically significant specimens were identified by the Vitek 2 Advanced Expert System. Antibiotic susceptibility testing was performed by the agar disc diffusion method and Etest. The strains were tested for the presence of blaVIM, blaIMP, blaKPC, blaNDM and blaOXA-48 genes by PCR. PFGE of chromosomal Xbal DNA digests was performed. A total of 3449 K. pneumoniae isolates were recovered during the last decade. Among them, 1668 (48 %) were carbapenemase-producing: 1333 (80%) K. pneumoniae carbapenemase (KPC)-, 286 (17%) Verona imipenemase (VIM), 45 (3%) KPC- and VIM-, and four New Delhi metallo-beta-lactamase (NDM)-producing. Their resistance rates to gentamicin, colistin and tigecycline were 41%, 23% and 16%, respectively. VIM-producing K. pneumoniae were isolated in 2005 and since 2008 have been endemic. KPC-producing K. pneumoniae (KPC-Kp) isolates were introduced in 2008 and until now represent the predominant carbapenemase-producing K. pneumoniae in our institution. PFGE of 97 KPC-Kp strains identified three types: A, 84 (87%); B, 11 (11%); and E, two (2%). Eleven co-producing KPC and VIM K. pneumoniae isolates belonged to PFGE B. The four NDM-positives were classified to type F. The number of K. pneumoniae bacteraemias increased during the study period, which may be solely attributed to the increase of carbapenemase-producing isolates. The threat of carbapenemase-producing K. pneumoniae emphasizes the urgent need for implementation of infection control measures and budgetary allocations to infection control.

  17. Results.

    ERIC Educational Resources Information Center

    Zemsky, Robert; Shaman, Susan; Shapiro, Daniel B.

    2001-01-01

    Describes the Collegiate Results Instrument (CRI), which measures a range of collegiate outcomes for alumni 6 years after graduation. The CRI was designed to target alumni from institutions across market segments and assess their values, abilities, work skills, occupations, and pursuit of lifelong learning. (EV)

  18. Examination of body burden and taint for Iceland scallop (Chlamys islandica) and American plaice (Hippoglossoides platessoides) near the Terra Nova offshore oil development over ten years of drilling on the Grand Banks of Newfoundland, Canada

    NASA Astrophysics Data System (ADS)

    DeBlois, Elisabeth M.; Kiceniuk, Joe W.; Paine, Michael D.; Kilgour, Bruce W.; Tracy, Ellen; Crowley, Roger D.; Williams, Urban P.; Gregory Janes, G.

    2014-12-01

    This paper presents results of analyses of body burdens of metals and hydrocarbons, and taste tests for taint, in Iceland scallop and American plaice performed as part of the Environmental Effects Monitoring (EEM) program for the Terra Nova offshore oil development (Grand Banks of Newfoundland, Canada). Scallop and plaice were collected in a Study Area located within approximately 1 km of drill centres at Terra Nova and in a Reference Area located approximately 20 km from the development. Samples were collected in 1997 to establish a baseline, and from 2000 to 2010, during drilling periods. Scallop adductor muscle tissue was contaminated with >C10-C21 aliphatic hydrocarbons resembling the drilling fluid in the synthetic drilling mud (SBM) used at Terra Nova in 2000, 2002 and 2004, but contamination of adductor muscle was not noted in 2006, 2008 and 2010. The maximum concentration in muscle was 28 mg/kg wet weight, noted in 2002. Scallop viscera was contaminated with hydrocarbons resembling drilling fluid in SBMs near drill centres in all EEM years except 2010. Viscera contamination with >C10-C21 hydrocarbons gradually decreased from a maximum of 150 mg/kg in 2000, to a maximum of 27 mg/kg in 2008; all values were below the laboratory reporting detection limit of 15 mg/kg in 2010. Therefore, evidence from both muscle and viscera indicates a decrease in tissue hydrocarbon contamination in recent years. Barium, another major constituent in drilling muds, has not been noted in scallop adductor muscles at concentrations above the reporting detection limit, but barium was detected in viscera in baseline and EEM years. The maximum concentration of barium in viscera during baseline sampling was 8 mg/kg. The maximum concentration in EEM years (29 mg/kg) was noted in 2000. The maximum concentration in 2010 was 25 mg/kg. The concentration of metals other than barium in scallop tissues was similar between the Terra Nova Study Area and the Reference Area. Hydrocarbons

  19. Development and clinical implementation of a new template for MRI-based intracavitary/interstitial gynecologic brachytherapy for locally advanced cervical cancer: from CT-based MUPIT to the MRI compatible Template Benidorm. Ten years of experience

    PubMed Central

    Richart Sancho, Jose; Otal Palacín, Antonio; Pérez-Calatayud, Jose; Santos Ortega, Manuel

    2016-01-01

    Purpose To study outcome and toxicity in 59 patients with locally advanced cervix carcinoma treated with computed tomography (CT)-based Martinez universal perineal interstitial template (MUPIT) and the new magnetic resonance imaging (MRI)-compatible template Benidorm (TB). Material and methods From December 2005 to October 2015, we retrospectively analyzed 34 patients treated with MUPIT and 25 treated with the TB. Six 4 Gy fractions were prescribed to the clinical target volume (CTV) combined with external beam radiotherapy (EBRT). The organs at risk (OARs) and the CTV were delineated by CT scan in the MUPIT implants and by MRI in the TB implants. Dosimetry was CT-based for MUPIT and exclusively MRI-based for TB. Dose values were biologically normalized to equivalent doses in 2 Gy fractions (EQD2). Results Median CTV volumes were 163.5 cm3 for CT-based MUPIT (range 81.8-329.4 cm3) and 91.9 cm3 for MRI-based TB (range 26.2-161 cm3). Median D90 CTV (EBRT + BT) was 75.8 Gy for CT-based MUPIT (range 69-82 Gy) and 78.6 Gy for MRI-based TB (range 62.5-84.2 Gy). Median D2cm3 for the rectum was 75.3 Gy for CT-based MUPIT (range 69.8-132.1 Gy) and 69.9 Gy for MRI-based TB (range 58.3-83.7 Gy). Median D2cm3 for the bladder was 79.8 Gy for CT-based MUPIT (range 71.2-121.1 Gy) and 77.1 Gy for MRI-based TB (range 60.5-90.8 Gy). Local control (LC) was 88%. Overall survival (OS), disease free survival (DFS), and LC were not statistically significant in either group. Patients treated with CT-based MUPIT had a significantly higher percentage of rectal bleeding G3 (p = 0.040) than those treated with MRI-based TB, 13% vs. 2%. Conclusions Template Benidorm treatment using MRI-based dosimetry provides advantages of MRI volume definition, and allows definition of smaller volumes that result in statistically significant decreased rectal toxicity compared to that seen with CT-based MUPIT treatment. PMID:27895682

  20. UPDATING AN EXPERT ELICITATION IN THE LIGHT OF NEW DATA: TEN YEARS OF PROBABILISTIC VOLCANIC HAZARD ANALYSIS FOR THE PROPOSED HIGH-LEVEL RADIOACTIVE WASTE REPOSITORY AT YUCCA MOUNTAIN, NEVADA

    SciTech Connect

    F.V. Perry; A. Cogbill; R. Kelley

    2005-08-26

    The U.S. Department of Energy (DOE) considers volcanism to be a potentially disruptive class of events that could affect the safety of the proposed high-level waste repository at Yucca Mountain. Volcanic hazard assessment in monogenetic volcanic fields depends on an adequate understanding of the temporal and spatial pattern of past eruptions. At Yucca Mountain, the hazard is due to an 11 Ma-history of basaltic volcanism with the latest eruptions occurring in three Pleistocene episodes to the west and south of Yucca Mountain. An expert elicitation convened in 1995-1996 by the DOE estimated the mean hazard of volcanic disruption of the repository as slightly greater than 10{sup -8} dike intersections per year with an uncertainty of about two orders of magnitude. Several boreholes in the region have encountered buried basalt in alluvial-filled basins; the youngest of these basalts is dated at 3.8 Ma. The possibility of additional buried basalt centers is indicated by a previous regional aeromagnetic survey conducted by the USGS that detected approximately 20 magnetic anomalies that could represent buried basalt volcanoes. Sensitivity studies indicate that the postulated presence of buried post-Miocene volcanoes to the east of Yucca Mountain could increase the hazard by an order of magnitude, and potentially significantly impact the results of the earlier expert elicitation. Our interpretation of the aeromagnetic data indicates that post-Miocene basalts are not present east of Yucca Mountain, but that magnetic anomalies instead represent faulted and buried Miocene basalt that correlates with nearby surface exposures. This interpretation is being tested by drilling. The possibility of uncharacterized buried volcanoes that could significantly change hazard estimates led DOE to support an update of the expert elicitation in 2004-2006. In support of the expert elicitation data needs, the DOE is sponsoring (1) a new higher-resolution, helicopter-borne aeromagnetic survey

  1. Analysis of DAX1 (NR0B1) and steroidogenic factor-1 (SF1/Ad4BP, NR5A1) in children and adults with primary adrenal failure: ten years' experience

    PubMed Central

    Lin, Lin; Gu, Wen-Xia; Ozisik, Gokhan; To, Wing S.; Owen, Catherine J.; Jameson, J. Larry; Achermann, John C.

    2007-01-01

    Context Primary adrenal failure is a life-threatening condition that can be caused by a range of etiologies, including autoimmune, metabolic, and developmental disorders. The nuclear receptors DAX1 (NR0B1) and steroidogenic factor-1 (SF1/Ad4BP, NR5A1) play an important role in adrenal development and function, and mutations in these transcription factors have been found in patients with adrenal hypoplasia. Objective To investigate the prevalence of DAX1 and SF1 mutations in children and adults with primary adrenal failure of unknown etiology (i.e., not caused by congenital adrenal hyperplasia, adrenoleukodystrophy, autoimmune disease). Patients One-hundred and seventeen patients were included. Eighty-eight individuals presented in infancy or childhood with adrenal hypoplasia or primary adrenal failure of unknown etiology (n=64, 46,XY phenotypic males; n=17, 46,XY gonadal dysgenesis/impaired androgenization; n=7, 46,XX females). Twenty-nine individuals presented in adulthood with “Addison disease” of unknown etiology. Methods Mutational analysis of DAX1 (NR0B1) (including exon 2α/1A) and SF1 (NR5A1) by direct sequencing. Results DAX1 mutations were found in 58% (37/64) of 46,XY phenotypic boys referred with adrenal hypoplasia, and in all boys (8/8) with hypogonadotropic hypogonadism and a family history suggestive of adrenal failure in males. SF1 mutations causing adrenal failure were found only in two patients with 46,XY gonadal dysgenesis. No DAX1 or SF1 mutations were identified in the adult-onset group. Conclusions DAX1 mutations are a relatively frequent cause of adrenal failure in this group of boys. SF1 mutations causing adrenal failure in humans are rare and are more likely to be associated with significant underandrogenization and gonadal dysfunction in 46,XY individuals. PMID:16684822

  2. Ten-year incident osteoporosis-related fractures in the population-based Canadian Multicentre Osteoporosis Study — Comparing site and age-specific risks in women and men

    PubMed Central

    Prior, Jerilynn C.; Langsetmo, Lisa; Lentle, Brian C.; Berger, Claudie; Goltzman, David; Kovacs, Christopher S.; Kaiser, Stephanie M.; Adachi, Jonathan D.; Papaioannou, Alexandra; Anastassiades, Tassos; Towheed, Tanveer; Josse, Robert G.; Brown, Jacques P.; Leslie, William D.; Kreiger, Nancy

    2016-01-01

    Background Population-based incident fracture data aid fracture prevention and therapy decisions. Our purpose was to describe 10-year site-specific cumulative fracture incidence by sex, age at baseline, and degree of trauma with/without consideration of competing mortality in the Canadian Multicentre Osteoporosis Study adult cohort. Methods Incident fractures and mortality were identified by annual postal questionnaires to the participant or proxy respondent. Date, site and circumstance of fracture were gathered from structured interviews and medical records. Fracture analyses were stratified by sex and age at baseline and used both Kaplan–Meier and competing mortality methods. Results The baseline (1995–97) cohort included 6314 women and 2789 men (aged 25–84 years; mean ± SD 62 ± 12 and 59 ± 14, respectively), with 4322 (68%) women and 1732 (62%) men followed to year-10. At least one incident fracture occurred for 930 women (14%) and 247 men (9%). Competing mortality exceeded fracture risk for men aged 65+ years at baseline. Age was a strong predictor of incident fractures especially fragility fractures, with higher age gradients for women vs. men. Major osteoporotic fracture (MOF) (hip, clinical spine, forearm, humerus) accounted for 41–74% of fracture risk by sex/age strata; in women all MOF sites showed age-related increases but in men only hip was clearly age-related. The most common fractures were the forearm for women and the ribs for men. Hip fracture incidence was the highest for the 75–84 year baseline age-group with no significant difference between women 7.0% (95% CI 5.3, 8.9) and men 7.0% (95% CI 4.4, 10.3). Interpretation There are sex differences in the predominant sites and age-gradients of fracture. In older men, competing mortality exceeds cumulative fracture risk. PMID:25451323

  3. Ten Years of Experience with the GORE EXCLUDER{sup Registered-Sign} Stent-Graft for the Treatment of Aortic and Iliac Aneurysms: Outcomes from a Single Center Study

    SciTech Connect

    Maleux, G. Claes, H.; Van Holsbeeck, A.; Janssen, R.; Laenen, A.; Heye, S.; Houthoofd, S.; Fourneau, I.

    2012-06-15

    Purpose: This study was designed to assess the long-term outcome of selected patients with aortic, aortoiliac, and isolated common iliac aneurysms treated with the GORE EXCLUDER{sup Registered-Sign} stent-graft. Methods: Between December 1998 and June 2010, 121 nonconsecutive patients underwent insertion of a GORE EXCLUDER{sup Registered-Sign} stent-graft to treat an aortic (n = 80; 66%), aortoiliac (n = 25; 21%), or isolated common iliac (n = 16; 13%) aneurysm. Procedural and follow-up data were collected prospectively. Primary endpoints are overall survival, intervention-free survival, and freedom from aneurysm rupture. Secondary endpoints are device- and procedure-related complications, including all types of endoleaks or endotension, and reintervention. Results: The mean follow-up is 4.98 years (standard deviation, 3.18; median follow-up, 4.05 years). The estimated percentage overall survival (with 95% confidence interval) after respectively 5 and 10 years of follow-up is 74.5% (65.8; 81.3) and 57.8% (47.7; 66.7). The estimated intervention-free survival after respectively 5 and 10 years is 90% (84.3; 96.1) and 77.7% (67; 88.4). There was no aneurysm rupture during follow-up. Early postoperative complications occurred in 16 patients (13%); none were fatal. Late reinterventions were performed in 18 patients (15%). Finally, throughout the follow-up period, endoleaks were identified: type I (n = 4; 3%); type II (n = 39; 32%); type III (n = 0; 0%); endotension was seen in 11 patients (9%). Conclusions: Aneurysm exclusion with use of the GORE EXCLUDER{sup Registered-Sign} stent-graft is durable through a mean follow-up of nearly 5 years. There was no postprocedural aneurysm rupture. Complications occurred throughout the follow-up period, requiring continued clinical and radiological surveillance.

  4. TEN-YEAR FOLLOW UP OF A PHASE II STUDY OF DOSE-INTENSE PACLITAXEL WITH CISPLATIN AND CYCLOPHOSPHAMIDE AS INITIAL THERAPY FOR POOR-PROGNOSIS ADVANCED-STAGE EPITHELIAL OVARIAN CANCER

    PubMed Central

    Sarosy, Gisele A.; Hussain, Mahrukh M.; Seiden, Michael V.; Fuller, A.F.; Nikrui, N.; Goodman, Annekathryn; Minasian, Lori; Reed, Eddie; Steinberg, Seth M.; Kohn, Elise C.

    2009-01-01

    SUMMARY Background To assess activity and toxicity in newly diagnosed advanced stage epithelial ovarian cancer (EOC) patients receiving dose-intense paclitaxel, cyclophosphamide, cisplatin, and filgrastim delivered with a flexible dosing schedule. Methods Patients with Stage III/IV EOC received cyclophosphamide 750 mg/m2, followed by 24 hr infusion of paclitaxel 250 mg/m2, and cisplatin 75 mg/m2 on day 2. Filgrastim began on day 3 at 10 μg/kg/d × 9d. Patients received six cycles of all drugs. Those with pathologic complete response or microscopic residual disease at the conclusion of six cycles of therapy received an additional cycles two to four cycles of paclitaxel with cyclophosphamide. Patients with objective response continued cyclophosphamide and paclitaxel. Results 62 patients were enrolled. Thirty-two of these 62 patients had stage IIIC disease, and 26 of 62 had stage IV disease. Using an intent to treat analysis, 55 (89%) experienced clinical complete remission (CCR). With a median potential follow-up of 11.4 years, the median progression free survival is 18.9 months and median survival is 5.4 years. The most serious toxicity was grade 3/4 neutropenic fever (35%). Although all participants developed peripheral neuropathy, improvement in neuropathic symptoms began with decrease or cessation of paclitaxel. Conclusions This regimen yielded a high response rate and encouraging overall survival. These data and those of the Japanese Gynecologic Oncology Group suggest that further study of dose dense or intense paclitaxel regimens in women with newly diagnosed advanced stage EOC is warranted. PMID:20091841

  5. Temperament and character in eating disorders: ten years of studies.

    PubMed

    Fassino, S; Amianto, F; Gramaglia, C; Facchini, F; Abbate Daga, G

    2004-06-01

    In recent years a number of studies of personality have been performed in subjects with Eating Disorders (EDs) to investigate the clinical differences between controls and ED patients and among EDs subtypes, and its role in the development and course of symptoms. The Tridimensional Personality Questionnaire (TPQ) and the Temperament and Character Inventory (TCI) have been widely used at this purpose, allowing the description of specific temperament and character profiles for EDs. High Harm Avoidance (HA) and low Self-Directedness (SD) are shared by all EDs. Slight differences on some facets have been found among ED subgroups. Nevertheless, HA is influenced by mood and both high HA and low SD are personality traits shared by many mental disorders, whose specificity is rather low. Restrictor anorectics are characterized by high Persistence (P) and a relatively higher SD, and bulimics by higher Novelty Seeking (NS) and the lowest SD, while binge/purging and purging anorectics share some traits with anorexia and some with bulimia. Though current data justify the discrimination among anorexia subtypes, they are not in contrast with the thesis of a continuum in ED personality traits. Since some personality traits display a prognostic value with regard to therapy and clinical outcome, further studies are needed on treatments and prognostic factors in EDs. Moreover, studies attempting to define the neurobiological and genetic correlates of temperament should be supported by clinical pharmacological trials.

  6. Ten Years of Research on Group Size and Helping.

    ERIC Educational Resources Information Center

    Latane, Bibb; Nida, Steve

    1981-01-01

    Reviewed research on the effect of the presence of other people on individuals' willingness to help in an emergency. Attention was paid to the nature of the precipitating incident; ambiguity of the helping situation; laboratory versus field settings; characteristics of subjects, victims, and bystanders; and communication among bystanders.…

  7. The Future Problem Solving Experience Ten Years After.

    ERIC Educational Resources Information Center

    Flack, Jerry

    1991-01-01

    Four young men who had participated in the national competition of the Future Problem Solving (FPS) Program 10 years earlier offer reflections about their FPS experience. Their coach concludes that the program equips young people with the vision and skills needed to anticipate and solve problems and build better tomorrows. (JDD)

  8. Vietnam 1963-1973: Ten Years of Operational Contract Support

    DTIC Science & Technology

    2014-05-22

    resources are allocated among alternative uses to satisfy human wants.”27 In an open marketplace, price is a reflection of supply and demand. In a...demand. This study uses Mansfield’s definition of economics, which is “the way in which resources are allocated among alternative uses to satisfy human...The deep-water ports maintained and operated twenty-eight deep-draft berths capable to receive military vessels. These deep-draft berths required

  9. Ten-Year-Old Students Solving Linear Equations

    ERIC Educational Resources Information Center

    Brizuela, Barbara; Schliemann, Analucia

    2004-01-01

    In this article, the authors seek to re-conceptualize the perspective regarding students' difficulties with algebra. While acknowledging that students "do" have difficulties when learning algebra, they also argue that the generally espoused criteria for algebra as the ability to work with the syntactical rules for solving equations is…

  10. The Mission of the Registrar: A Ten-Year Retrospective

    ERIC Educational Resources Information Center

    Lanier, David C.

    2006-01-01

    Records management, database management, and business process management--what do they have to do with the mission of the registrar? This article takes a look at how well the 1995 article, "The Mission of the Registrar Today," did in predicting the direction of the registrar's profession and makes some new predictions about future responsibilities…

  11. Ten Years in the Life of Russian Libraries.

    ERIC Educational Resources Information Center

    Greening, Joyce Martin

    1995-01-01

    Examines the effects of the political events of the last decade on Russian libraries. Topics include libraries in the old Soviet Union, decentralization of control and financing, relaxation of censorship, changes in the Russian publishing industry, channels of distribution, and future needs. (LRW)

  12. Management of Acute Osteomyelitis: A Ten-Year Experience

    PubMed Central

    Helm, Caitlin; Huschart, Emily; Kaul, Rajat; Bhumbra, Samina; Blackwood, R. Alexander; Mukundan, Deepa

    2016-01-01

    Osteomyelitis is an infection of the bone; proper management requires prolonged antibiotic treatment. Controversy exists as to when a patient should transition from intravenous to oral antibiotics. However, due to the high bioavailability of some oral antibiotics, optimal time to transition from high to low bioavailability antibiotics is a more valid consideration. Additionally, there are questions surrounding the efficacy of certain antibiotics, specifically trimethoprim-sulfamethoxazole (TMP-SMX), in treating osteomyelitis. After obtaining Institutional Review Board approval from both universities, a retrospective chart review was conducted, utilizing an author-created severity scale, on all patients seen by Pediatric Infectious Diseases at the Universities of Michigan and Toledo with an acute osteomyelitis diagnosis from 2002-2012. There were 133 patients, 106 treated successfully. Success was defined in this study specifically as treatment of <14 weeks without recurrence within 30 days of stopping antibiotics or permanent site disability. Seventeen patients were treated with TMP-SMX at comparable cure rates. Patients with pre-existing bone defects (noted in radiological reports), initial erythrocyte sedimentation rate (ESR)≥70, hematogenous osteomyelitis with soft tissue extension, and skull osteomyelitis were associated with increased failure rate. Switch to low bioavailability antibiotics occurred, on average, at 3.5 weeks; however, switching before then was not associated with decreased cure rate. As prevalence of methicillin-resistant Staphylococcus aureus (MRSA), especially clindamycin-resistant MRSA, increases, TMP-SMX appears to be an acceptable antibiotic. There does not appear to be a minimum length of high bioavailability treatment required for cure. Prior bone defect, extensive infection, ESR≥70, or skull osteomyelitis may be indications for more aggressive management.

  13. Ten Years of Shock Tube Research at Marseille

    NASA Astrophysics Data System (ADS)

    Houas, L.

    The invention of the shock tube is attributed to Paul Vieille [1] in the late 19th century. The first simplest shock tube was composed of two chambers separated by a diaphragm.With the pressure increase in the first chamber causing the diaphragm rupture, a shock wave was generated and propagated with a supersonic velocity in the second chamber.

  14. Collection Overview: Ten Years of Wonderful Open Access Science

    PubMed Central

    Roberts, Roland G.; Alfred, Jane

    2013-01-01

    To mark our tenth Anniversary at PLOS Biology, we are launching a special, celebratory Tenth Anniversary PLOS Biology Collection which showcases 10 specially selected PLOS Biology research articles drawn from a decade of publishing excellent science. It also features newly commissioned articles, including thought-provoking pieces on the Open Access movement (past and present), on article-level metrics, and on the history of the Public Library of Science. Each research article highlighted in the collection is also accompanied by a PLOS Biologue blog post to extend the impact of these remarkable studies to the widest possible audience. PMID:24167446

  15. The Ten-Year History of the Asklepios Study

    PubMed Central

    Park, Jeong Bae

    2015-01-01

    The Asklepios study started 10 years ago when 2,500 subjects were screened between 2002 and 2004. And all of the 90+ publications we have for the moment are from those cross-sectional data. This is called round 1. Since 2011, in round 2, all of those patients have started to come back for a 10-year follow-up. At this moment, approximately 1,750 of those patients have been seen. The patients were followed by general practitioners (GP), and the GP again provided the information about what has happened with the medical status in the past 10 years including drug therapy: not only the drugs that they are taking at the moment were evaluated, but, because patients often use many drugs, the chronicles of drugs for major risk factors, for hypertension, lipids, contraceptives and more. Then, patients come to the study center where the same cluster of examinations are undertaken by one single doctor, Prof. Ernst R. Rietzschel and one study nurse, just like 10 years ago. Again, using a single observer at the two time frames has kept the methodology very strict. PMID:26587452

  16. Ovarian Kaleidoscope Database: Ten Years and Beyond1

    PubMed Central

    Hsueh, Aaron J.; Rauch, Rami

    2012-01-01

    ABSTRACT Ovarian Kaleidoscope database (OKdb) is an online, searchable, public database containing text-based and DNA microarray data to facilitate research by ovarian researchers. Using key words and predetermined categories, users can search ovarian gene information based on gene function, cell type of expression, cellular localization, hormonal regulation, mutant phenotypes, chromosomal location, ligand-receptor relationship, and other criteria, either alone or in combination. For individual genes, users can access more than 10 extensive DNA microarray datasets to interrogate gene expression patterns in a development-specific and cell type-specific manner. All ligand and receptor genes expressed in the ovary are matched to facilitate investigation of paracrine/autocrine signaling. More than 3500 ovarian genes in the database are matched to 185 gene pathways in the Kyoto Encyclopedia of Genes and Genomes to allow for elucidation of gene interactions and relationships. In addition to >400 genes with infertility or subfertility phenotypes when mutated in mice or humans, the OKdb also lists ∼50 and ∼40 genes associated with polycystic ovarian syndrome and primary ovarian insufficiency, respectively. The expanding OKdb is updated weekly and allows submission of new genes by ovarian researchers to allow instant access to DNA microarray datasets for newly submitted genes. The present database is a virtual community for ovarian researchers and allows users to instantaneously provide their comments for individual gene pages based on an automated Web-discussion system. In the coming years, we will continue to add new features to serve the ovarian research community. PMID:22441797

  17. Undiscovered public knowledge: A ten-year update

    SciTech Connect

    Swanson, D.R.; Smalheiser, N.R.

    1996-12-31

    Two literatures or sets of articles are complementary if, considered together, they cart reveal useful information of scientific interest not apparent in either of the two sets alone. Of particular interest are complementary literatures dud are also mutually isolated and noninteractive (they do not cite each other and are not co-cited). In that case, the intriguing possibility arises that the information gained by combining them is novel. During the past decade, we have identified seven examples of complementary noninteractive structures in the biomedical literature. Each structure led to a novel, plausible, and testable hypothesis that, in several cases, was subsequently corroborated by medical researchers through clinical or laboratory investigation. We have also developed, tested, and described a systematic, computer-aided approach to finding and identifying complementary noninteractive literatures.

  18. Ten Years down the Road: Predictors of Driving Cessation

    ERIC Educational Resources Information Center

    Edwards, Jerri D.; Bart, Edward; O'Connor, Melissa L.; Cissell, Gayla

    2010-01-01

    Purpose: Recent prospective studies have found that cognition is a more salient predictor of driving cessation than physical performance or demographic factors among community-dwelling older adults. However, these studies have been limited to 5 years of follow-up. The current study used data from the Maryland Older Drivers Project to examine…

  19. The Higher Education Prison Program: The First Ten Years.

    ERIC Educational Resources Information Center

    Tobin, Patricia L.

    The first 10 years of operation of the college-in-prison program in Massachussetts and characteristics of participating offenders were assessed. College credit courses have been offered to inmates in adult corrections facilities by The University of Massachusetts at Boston through a program called the Higher Education Prison Program (HEPP).…

  20. Chernobyl and Bhopal ten years on comparisons and contrasts

    SciTech Connect

    Grimston, M.C.

    1997-03-01

    Within eighteen months in mid- 1980s, two of the most serious industrial accidents in history occurred. At Bhopal, capital of Madhya Pradesh in central India, in the early hours of December 3, 1984, an explosion occurred at Union Carbide of India Ltd (UCIL)`s methyl isocyanate plant. Some 40 tonnes of a complex chemical mixture were released, causing several thousand deaths and hundreds of thousands of injuries. At Chernobyl in the north of Ukraine, then part of the USSR, in the early hours of April 26, 1986, an explosion at a state-owned nuclear power plant caused the release of some 6 tonnes (possibly more) of radioactive materials. The {open_quote}immediate{close_quote} death toll was much lower than at Bhopal. The usually-quoted figure of 30, all of whom were on site in the immediate aftermath of the explosion, includes two who died on site from burns and falling masonry and 28 who died within the following few weeks from Acute Radiation Syndrome. (Another person on site died of a heart attack, which it is difficult to associate directly with the accident.) However, the effects of the accident were widespread, especially in Belarus, Ukraine and Russia, and theoretical calculations suggest that further illness and premature deaths are to be expected for several years to come. This paper compares and contrasts these two accidents. There are striking similarities.

  1. Ten-year follow-up of a giant prolactinoma.

    PubMed

    Fernandes, Vera; Santos, Maria Joana; Almeida, Rui; Marques, Olinda

    2015-11-20

    Giant prolactinomas are rare pituitary tumours of which management can be a challenge. A 28-year-old man presented with headaches, visual impairment and behavioural changes. Clinically, the patient was found to have hypogonadism and bitemporal hemianopsia. A MRI demonstrated a pituitary tumour 76 mm in diameter and blood tests revealed a serum prolactin of 158,700 µU/mL (reference range 58-254). Initially, a craniotomy was performed. Immunohistochemistry of the tumour identified a prolactinoma with a high proliferative index and the patient was started on treatment with a dopamine agonist. A year later, neurological symptoms worsened due to regrowth of the lesion's cystic component, and so further surgery was performed. After 10 years of treatment with dopamine agonists, the prolactin levels decreased by 96.8%, there was an effective reduction in tumour size, and the neurological signs and symptoms resolved.

  2. Emergency department complaints: a ten-year review.

    PubMed

    Ooi, S B

    1997-03-01

    This 10-year (May 1986-31 December 1995) retrospective study was done to analyse the types of complaints received by the National University Hospital's Emergency Department (NUH EMD), so as to take remedial measures. It was done by reviewing three sources of complaints received by the department, namely formal written complaints, verbal feedback received by the Corporate Affairs Department, and via feedback forms. The areas of complaints looked for included the nature, number, validity, whether remediable and triage priority of the patients. One hundred and eighty-eight subcategories of complaints were received from 169 complaints. The complaint frequency was 0.26 per 1,000 visits or 1 complaint per 3,846 visits. The complaint frequency over the 10 years did not vary much (range 0 to 0.44). Most of the complaints are divided into 4 broad categories ie medical, doctor-patient/paramedical staff-patient relationship, patient flow/logistics at EMD and in-house complaints. The majority (71.3%) of the complaints were due to medical and doctor-patient relationship problems. Complaints tend to arise from Priority 2 and 3 rather than Priority 1 patients. 33.7% of the complaints were considered valid, 21.6% not valid while in the remaining 44.7%, validity could not be determined. 48.4% of complaints were likely to be remediable. Based on this study, we have since instituted a compulsory emergency department-driven "Customer Service Training Programme" and weekly teaching sessions for each incoming group of medical officers posted to the NUH EMD.

  3. Sunspot Numbers from ISOON: A Ten-Year Data Analysis

    NASA Astrophysics Data System (ADS)

    Balasubramaniam, K. S.; Henry, T. W.

    2016-11-01

    Sunspot numbers are important tracers of historical solar activity. They are important in predicting the oncoming solar maximum, in the design of lifetimes of space assets, and in assessing the extent of solar-radiation impact on the space environment. Historically, sunspot numbers have been obtained visually from sunspot drawings. The availability of digital images from the US Air Force Improved Solar Optical Observing Network (ISOON) prototype telescope concurrent to observer-dependent sunspot numbers recorded at the National Solar Observatory (NSO) has provided a basis for comparing sunspot numbers determined from the two methods. We compare sunspot numbers from visual and digital methods observed nearly simultaneously. The advantages of digital imagery are illustrated.

  4. The Learning Organization Ten Years On: A Case Study.

    ERIC Educational Resources Information Center

    Smith, Peter A. C.

    1999-01-01

    A learning organization is viable when the learning climate successfully changes managers' mindsets. A case study of a financial services enterprise illustrates ways to keep mind sets from hardening and shows how changing learning activities and tools can change habits of thinking and learning. (Contains 30 references.) (SK)

  5. Embryo stem cell research: ten years of controversy.

    PubMed

    Robertson, John A

    2010-01-01

    This overview of 10 years of stem cell controversy reviews the moral conflict that has made ESCs so controversial and how this conflict plays itself out in the legal realm, focusing on the constitutional status of efforts to ban ESC research or ESC-derived therapies. It provides a history of the federal funding debate from the Carter to the Obama administrations, and the importance of the Raab memo in authorizing federal funding for research with privately derived ESCs despite the Dickey-Wicker ban on federal funding of embryo research. It also reviews the role that scientists themselves have played in developing regulations for ESC research, the emergence of ESCROs as special review bodies for ESC research, and the thorough consent requirements for donation of IVF embryos to ESC research. With research now transitioning from the lab to the clinic, the article reviews the challenges of ensuring safety and consent in translational research. It concludes with a call for respecting those persons who have to using or working with ESC products and an account of how obtaining stem cells from a person's own cells will alleviate some but not all of the controversy surrounding ESC research.

  6. A Roadmap for IT Leadership and the Next Ten Years

    ERIC Educational Resources Information Center

    Chester, Timothy M.

    2006-01-01

    Shortly after becoming a CIO (Chief Information Officer), the author read an article by Gregory Jackson in the January 2004 Chronicle of Higher Education entitled, "A CIO's Question: Will You Still Need Me When I'm 64?" Jackson, one of the most widely known and respected CIOs in higher education, argued that CIOs in higher education face four…

  7. Ten years of integrated care for the older in France

    PubMed Central

    Somme, Dominique; de Stampa, Matthieu

    2011-01-01

    Background This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population. Policies Over the last 10 years, the French health care system has been principally influenced by two competing linkage models that failed to integrate social and health care services: local information and coordination centers, governed by the social field, and the gerontological health networks governed by the health field. In response to this fragmentation, Homes for the Integration and Autonomy for Alzheimer patients (MAIAs) is currently being implemented at experimental sites in the French national Alzheimer plan, using an evidence-based model of integrated care. In addition, the state’s reforms recently created regional health agencies (ARSs) by merging seven strategic institutions to manage the overall delivery of care. Conclusion The French health care system is moving from a linkage-based model to a more integrated care system. We draw some early lessons from these changes, including the importance of national leadership and governance and a change management strategy that uses both top-down and bottom-up approaches to implement these reforms. PMID:22375101

  8. Ten years of Developing International Volcanology Graduate Study Programs

    NASA Astrophysics Data System (ADS)

    Rose, W. I.

    2010-12-01

    In 2000 I reported at this symposium about multi-institutional graduate field trips to IAVCEI events, such as the Bali meeting and its importance in building international collegiality and awareness among the volcanology doctoral students. NSF was an enthusiastic supporter of these field sessions and this support has continued through the highly successful Pucon and Reykjavik sessions. International volcanology graduate program development began with several exchange programs. EHaz was a highly successful program (McGill, Simon Fraser, Michigan Tech, Buffalo, UNAM and Universidad de Colima) funded by the Department of Education (FIPSE) that moved students across North America where dozens of graduate students spent semesters of their study abroad and shared annual field trips and online student led graduate seminar classes. Michigan Tech’s volcanology graduate program started a Masters International program that combined Peace Corps service with hazards mitigation graduate study and students were placed by Peace Corps in countries with prominent natural hazards. The new program funded 2 year residences in foreign environments, principally in Pacific Latin America. NSF strongly supported this program from its inception, and eventually it gained NSF PIRE support. Dozens of students have initiated the 3 year program (15 completed) to date. A similar PIRE developed at UAF with a link to volcanology in the Russian Far East. One gain is the development of many socially-conscious research selections. Beginning this year transatlantic dual degree masters programs in volcanology are being offered by a consortium of US and European volcanology programs (Michigan Tech, Buffalo, Clermont Ferrand and University of Milan Bicocca), again aided by FIPSE funding. Students have dual advisors on both sides of the Atlantic and spend about half of their two year programs in Europe and half in US. Faculty also travel in the program and the four campuses are increasingly linked by coursework and research networks. Because the international developments of volcanology programs address the need for more robust coursework and research choices for students than are possible on one campus, and because they lead to a diverse network of professional contacts , we think the next decade will bring many more multi-university volcanology programs linked to field sites all over the world.

  9. Ten years of HPV vaccines: State of art and controversies.

    PubMed

    Angioli, Roberto; Lopez, Salvatore; Aloisi, Alessia; Terranova, Corrado; De Cicco, Carlo; Scaletta, Giuseppe; Capriglione, Stella; Miranda, Andrea; Luvero, Daniela; Ricciardi, Roberto; Montera, Roberto; Plotti, Francesco

    2016-06-01

    The human papillomavirus (HPV) represents one of the most common sexually transmitted infections and it has been related to cervical cancer. The HPV vaccines prevent infection with certain species of HPV associated with the development of cervical cancer or genital warts. We carried out a PubMed search up to 2015 evaluating all randomized studies published in literature. This review discusses the current status of HPVs vaccines on the global market, efficacy, safety profiles, controversies and future vaccine developments. Three HPVs vaccines are currently on the global market: bivalent, quadrivalent and ninevalent. Bivalent and quadrivalent vaccines can protect against almost 70% of cervical HPV-related cancerous and precancerous conditions and the ninevalent vaccine, instead, provides a protection against almost 90%. The use of vaccinations raised several controversies in the last years and, currently, is not possible to establish which type of vaccine is most effective, however all of them are safe.

  10. College Student Behavior: A Ten-Year Look.

    ERIC Educational Resources Information Center

    Lester, Lewis F.; Leach, Jonathan H.

    1983-01-01

    A survey of college students' behavior found that hedonism has increased during the past 10 years, based on measures of sexual activity and alcohol and marijuana use before and during college. Differences observed 10 years earlier in the behavior of male and female students have largely disappeared. (Authors/PP)

  11. Raccoon Mountain pumped-storage plant: Ten years operating experience

    SciTech Connect

    Adkins, F.E.

    1987-09-01

    Operational experience at the 1 530 MW Raccoon Mountain underground pumped-storage plant can be relevant to other large hydro facilities. A number of unusual features were incorporated and individual unit size was only recently overtaken elsewhere. Direct water cooling of rotor and stator winding has been successfully applied to salient pole machines. A number of problems, including difficulties with oil-filled 161 kV current transformers, and some mechanical aspects, are reported. Designed for remote supervisory control, the plant has required closer attention. Operating statistics are included.

  12. Michigan Public School Finance: The Last Ten Years.

    ERIC Educational Resources Information Center

    Phelps, James L.; Addonizio, Michael F.

    1983-01-01

    Following adoption of a district power equalizing school aid formula intended to achieve equity in the distribution of general revenue, in per pupil expenditure, and in property taxes, significant progress was made toward attaining wealth neutrality that has subsequently been eroded by a depressed state economy. (MJL)

  13. Sight-Singing: Ten Years of Published Research

    ERIC Educational Resources Information Center

    Kuehne, Jane M.

    2010-01-01

    The purpose of this article was to review published research on sight-singing from the past 10 years, 1998-2008. Several authors published research in various areas in sight-singing. These included festival availability and participation, time use in sight-singing adjudication, method and materials, strategies of successful students, assessing…

  14. Methadone-related deaths. A ten year overview.

    PubMed

    Vignali, Claudia; Stramesi, Cristiana; Morini, Luca; Pozzi, Fulvia; Groppi, Angelo

    2015-12-01

    Over the last 10 years we have registered in our district (about 500,000 inhabitants) 36 cases of fatal methadone poisoning, involving both patients on treatment and naive subjects: this is a significant increase of deaths due to methadone use, misuse or abuse compared with previous years. Twenty-four patients (66.7%) were on methadone maintenance programs for heroin detoxification, while 12 (33.3%) were taking the drug without a medical prescription. The average blood concentration of methadone in patients undergoing a maintenance program was 1.06 mg/L (0.21-3.37 mg/L), against 0.79 mg/L (0.2-3.15 mg/L) in those taking the non-prescribed drug. Since 111 heroin-related deaths were recorded in our district in the same period, the fact that there appear to be many methadone deaths (about a third of heroin-related deaths) cannot be overlooked. The aim of this work is to understand the possible reasons for such a large number of methadone-related deaths. On this subject, we have noticed that risks associated with methadone intake are often underestimated by clinicians prescribing the drug: sometimes methadone is prescribed without taking into account patient's tolerance to opiates, and a large number of subjects enrolled in methadone maintenance programs in Italy, have also been given take-home doses, thus increasing the risk of abuse and diversion.

  15. Androgen insensitivity syndrome: ten years of our experience.

    PubMed

    Subramaniam, Amudha; Singh, Rajender; Tilak, Preetha; Devi, Rema; Kulandaivelu, Mahalingam; Kumarasamy, Thangaraj

    2013-01-01

    Abnormalities of secondary sexual differentiation manifest in varying degrees depending upon the severity of the underlying cause. Primary amenorrhea in phenotypic females is caused by several different factors, including hormonal imbalance, nutritional deficiency and sex differentiation abnormalities. Androgen insensitivity syndrome (AIS) accounts for a large proportion of such cases in phenotypic females but genetically male individuals. Over the past 10 years, we have collected data related to androgen insensitivity from more than 150 cases. The research identified several important but neglected facts about this syndrome; including the identification of mutations in 39% of the cases and the establishment of the cause of pathogenesis in 60% of them. The most intriguing facts were uncovered in relation to late presentation of the AIS cases, little awareness among patients and family members, no consensus on the age of performing gonadectomy, and reluctance of the patients to undergo recommended surgery. These issues need immediate attention to improve healthcare and management of AIS cases. This article summarizes our observations about AIS with an aim to spread awareness among patients and clinicians.

  16. Ten-years experience of laser use in aesthetic surgery

    NASA Astrophysics Data System (ADS)

    Gulev, Valerii S.; Dobrjakova, Olga B.; Dobrjakov, Boris S.

    2001-10-01

    A collaboration of the laser physicist and aesthetic surgeons has started 10 years ago. Within the period 1992 - 2000 we have carried out the investigation of the influence of the pulsed radiation, emitted by lasers having as active mediums crystals of the aluminum-yttrium garnet and alexandrite, on the cultures of the alive tissue and the fibrosis capsules around foreign bodies in the animals. Besides, we have studied the clinical protocol: in majority, patients were women after mammary augmentation. The laser tatoo non-invasive removals were marked at the beginning of the pulse of the Q-switch neodymium yttrium-aluminum garnet laser radiation used in human. It was obtained that this laser radiation broke the cell proliferation without any mutations and morphology changes. It was also noticed much evidence that the high functional fibroblast activities were registered in fibrosis capsules of not exposed animals to the laser radiation. It was also noticed that the use of laser radiation affected the speed and quality of the productive inflammation. The softening of the fibrous capsule around the mammary implant and the reduction of the pronounced rubbers were the clinical effects of the laser radiation.

  17. Reculturing Educational Leadership: The ISLLC Standards Ten Years Out.

    ERIC Educational Resources Information Center

    Murphy, Joseph

    Over the last 25 years, the field of school administration has experienced turmoil as it has struggled to grow out of its adolescence. A good deal of energy has been invested in coming to grips with the question of what ideas should shape school administration. This paper chronicles the role of one of the most significant reshaping initiatives to…

  18. A Ten Year Citation Analysis of Major Australian Research Institutions

    ERIC Educational Resources Information Center

    Batterham, Robin J.

    2011-01-01

    The introduction of the Excellence in Research for Australia scheme has heightened debate amongst research institutions over the use of metrics such as citations, especially given the ready availability of citation data. An analysis is presented of the citation performance of nine Australian universities and the Commonwealth Scientific, Industrial…

  19. Ten Years of Cybertech: The Educational Benefits of Bullfighting Robotics

    ERIC Educational Resources Information Center

    Hernando, M.; Galan, R.; Navarro, I.; Rodriguez-Losada, D.

    2011-01-01

    After 10 years of organizing the Cybertech robotics competition, this paper presents this unique and innovative educational experience of teaching engineering at Universidad Politecnica de Madrid (UPM), Spain. Cybertech is not only a well-known robotic contest in Spain due to the "Robotaurus" bullfighting, but is also a whole academic…

  20. Ten years of tiotropium: clinical impact and patient perspectives.

    PubMed

    Yohannes, Abebaw M; Connolly, Martin J; Hanania, Nicola A

    2013-01-01

    Tiotropium bromide is an anticholinergic agent that has gained worldwide acceptance as a first-line, once daily maintenance therapy for patients with moderate-to-severe chronic obstructive pulmonary disease. The purpose of this review is to synthesize the evidence base in the past 10 years on the development of tiotropium and its efficacy compared to other able interventions such as long-acting beta agonists (LABAs), as well as to assess its safety profile and its effects on health-related outcomes in patients with COPD. Treatment with tiotropium bromide has generally improved patients' health-related quality of life, reduced the number of patients suffering from acute exacerbations, decreased the number of hospitalizations, improved dyspnea, and reduced adverse events compared to placebo. In the past decade, several studies have examined the safety and efficacy of tiotropium in comparison to placebo and to LABAs (salmeterol, formoterol, and indacaterol) over periods ranging from 3 months to 48 months of follow-up. Head-to-head comparisons of tiotropium 18μg (once daily) with salmeterol 50μg (twice daily) in well-controlled trials demonstrated that tiotropium was superior in reducing acute exacerbation events and in improving quality of life. In a few short-term studies, indacaterol was comparable to tiotropium in its efficacy in improving health-related outcomes. Although the safety record of tiotropium has been exemplary in comparison to placebo, anticholinergic events such as dry mouth can be encountered in some patients. While the long-term safety of tiotropium when delivered in the HandiHaler® has been well documented, its delivery using the Respimat® Soft Mist Inhaler™ was associated with an elevated risk of cardiovascular complications, including increased mortality when compared to placebo. The exact mechanism for this is not known but is being investigated in a large multinational study that will evaluate the long-term safety of different doses of tiotropium delivered by the Respimat® soft mist inhaler versus the HandiHaler®. Further studies are required to investigate the efficacy and safety of tiotropium in comparison with novel LABAs such as indacaterol and vilanterol, and with other emerging novel anticholinergic agents such as aclidinium bromide and NVA237 (glycopyrronium bromide).

  1. Investigating Ten Years of Equity Policy in Australian Higher Education

    ERIC Educational Resources Information Center

    Coates, Hamish; Krause, Kerri-Lee

    2005-01-01

    This paper reports issues arising from a longitudinal study of 1991 to 2002 Australian higher education equity data. The national equity framework uses an empirical performance indicator system to monitor access, participation, success and retention of six designated equity groups. The paper examines three possible approaches for defining new…

  2. Laser Fusion: The First Ten Years 1962-1972

    SciTech Connect

    Kidder, R E

    2006-07-06

    This account of the beginning of the program on laser fusion at Livermore in 1962, and its subsequent development during the decade ending in 1972, was originally prepared as a contribution to the January 1991 symposium 'Achievements in Physics' honoring Professor Keith Brueckner upon his retirement from the University of San Diego at La Jolla. It is a personal recollection of work at Livermore from my vantage point as its scientific leader, and of events elsewhere that I thought significant. This period was one of rapid growth in which the technology of high-power short-pulse lasers needed to drive the implosion of thermonuclear fuel to the temperature and density needed for ignition was developed, and in which the physics of the interaction of intense light with plasmas was explored both theoretically and experimentally.

  3. Collection overview: ten years of wonderful open access science.

    PubMed

    Roberts, Roland G; Alfred, Jane

    2013-10-01

    To mark our tenth Anniversary at PLOS Biology, we are launching a special, celebratory Tenth Anniversary PLOS Biology Collection which showcases 10 specially selected PLOS Biology research articles drawn from a decade of publishing excellent science. It also features newly commissioned articles, including thought-provoking pieces on the Open Access movement (past and present), on article-level metrics, and on the history of the Public Library of Science. Each research article highlighted in the collection is also accompanied by a PLOS Biologue blog post to extend the impact of these remarkable studies to the widest possible audience.

  4. Chandra: Ten Years of Amazing Science with a Great Observatory

    NASA Technical Reports Server (NTRS)

    Weisskopf, Martin C.

    2009-01-01

    We review briefly review the history of the development of the Chandra X-Ray Observatory, highlighting certain details that many attendees of this Conference might not be aware of. We then present a selection of scientific highlights of the first 10 years of this remarkable and unique mission.

  5. Ten Years of Cloud Optical and Microphysical Retrievals from MODIS

    NASA Technical Reports Server (NTRS)

    Platnick, Steven; King, Michael D.; Wind, Galina; Hubanks, Paul; Arnold, G. Thomas; Amarasinghe, Nandana

    2010-01-01

    The MODIS cloud optical properties algorithm (MOD06/MYD06 for Terra and Aqua MODIS, respectively) has undergone extensive improvements and enhancements since the launch of Terra. These changes have included: improvements in the cloud thermodynamic phase algorithm; substantial changes in the ice cloud light scattering look up tables (LUTs); a clear-sky restoral algorithm for flagging heavy aerosol and sunglint; greatly improved spectral surface albedo maps, including the spectral albedo of snow by ecosystem; inclusion of pixel-level uncertainty estimates for cloud optical thickness, effective radius, and water path derived for three error sources that includes the sensitivity of the retrievals to solar and viewing geometries. To improve overall retrieval quality, we have also implemented cloud edge removal and partly cloudy detection (using MOD35 cloud mask 250m tests), added a supplementary cloud optical thickness and effective radius algorithm over snow and sea ice surfaces and over the ocean, which enables comparison with the "standard" 2.1 11m effective radius retrieval, and added a multi-layer cloud detection algorithm. We will discuss the status of the MOD06 algorithm and show examples of pixellevel (Level-2) cloud retrievals for selected data granules, as well as gridded (Level-3) statistics, notably monthly means and histograms (lD and 2D, with the latter giving correlations between cloud optical thickness and effective radius, and other cloud product pairs).

  6. A Report on a Ten Year Old Public University

    ERIC Educational Resources Information Center

    Cordeiro, William P.; Muraoka, Dennis

    2014-01-01

    California State University Channel Islands (CI) was founded in 2001 (in Camarillo, CA) and admitted its first students in 2002. Over the ensuing decade, the campus has transitioned from a start-up institution to a regionally accredited comprehensive university offering 23 baccalaureate and 6 graduate degree programs. This transition has occurred…

  7. Permitting of Landfill Bioreactor Operations: Ten Years after ...

    EPA Pesticide Factsheets

    Prior to promulgation of the Rule, there were approximately 20 full-scale bioreactor projects in North America, including one in Canada. Of these, six were permitted by EPA (four Project XL sites and two projects listed separately under a cooperative research agreement at the Outer Loop Landfill in Kentucky). In March 2014, there were about 40 bioreactor projects reported, including 30 active RD&D projects in 11 approved states and one project on tribal lands. Wisconsin features the largest number of projects at 13, due primarily to the fact that landfill owners in the state must either eliminate landfill disposal of biodegradable materials or to achieve the complete stabilization of deposited organic waste at MSW landfills within 40 years after closure. Most landfill operators have selected a bioreactor approach to attempt to achieve the latter goal. In summary, only 16 of 50 (32%) states have currently adopted the Rule, meaning that development of RD&D permitting procedures that are consistent with EPA’s requirements has generally not occurred. The predominant single reason cited for not adopting the Rule was lack of interest amongst landfill facilities in the state. Subtitle D and its state derivatives already allow leachate recirculation over prescriptive (i.e., minimum technology) liner systems, which is often the primary goal of site operators seeking to control leachate treatment costs. Other reasons related to concerns over increased time, cost

  8. [The results of research conducted at the Stefan S. Nicolau Institute of Virology on the herpes simplex virus].

    PubMed

    Muţiu, A

    1989-01-01

    The report is a review of the research and results of the "Stefan S. Nicolau" Institute of Virology scientists in the field of herpes viruses, as they were materialized in the great number of published or communicated scientific papers these last ten years.

  9. The Status of Mathematics Achievement in Two Elementary Schools in Palau: 1984-1990. A Report to the Ministry of Education.

    ERIC Educational Resources Information Center

    King, Irvin L.; Emesiochl, Masa-Aki

    When the Trust Territory of the Pacific Islands gradually dissolved in the 1980s, the Republic of Palau assumed a greater responsibility for its own education system. In order to monitor the mathematical achievement of elementary school students during the transition from external to local control of educational procedures, basic skills…

  10. A ten-year history of the demography and productivity of an Arctic wolf pack

    USGS Publications Warehouse

    Mech, L.D.

    1995-01-01

    A pack of two to eight adult wolves (Canis lupus arctos) and their pups was observed during ten summers (1986-95) on Ellesmere Island, Northwest Territories, Canada. The author habituated the wolf pack to his presence in the first summer and reinforced the habituation each summer thereafter. The first alpha female produced four to six pups each year between 1986 and 1989. However, her daughter, who succeeded her as the alpha female, produced only one to three pups each year between 1990 and 1992 and in 1994, and apparently did not whelp in 1993 or in 1995. The tenure of the first alpha male was at least two years, and his successor was alpha male for the remaining eight years of the study. The wolf pack was characterized by highly variable annual productivity. The second alpha male-and-female breeding pair likely was an older brother and a younger sister. Early survival of wolf pups was high and constant, with all pups surviving through August of their first year. The pack's demography was consistent with what is known for wolf packs in other regions of North America, but its productivity was more typical of arctic packs.

  11. Ten Years after Patten: Young People and Policing in Northern Ireland

    ERIC Educational Resources Information Center

    Byrne, Jonny; Jarman, Neil

    2011-01-01

    Through a comprehensive review of existing literature, this article documents young people's experiences of policing during the period of political transition and extensive reform of the structures of policing in Northern Ireland since the publication of the Independent Commission on Policing for Northern Ireland (The Patten Report) in 1999. The…

  12. Ten Year Study of Drug and Alcohol Usage at Middle Tennessee State University.

    ERIC Educational Resources Information Center

    Heritage, Jeannette

    This study involved the third administration of a survey of drug and alcohol use among students at Middle Tennessee State University. The original study was completed in 1977 (N=1,551), the second in 1983 (N=1,198), and the third in 1987 (N=1,535). Findings from the 1987 survey revealed that females and fraternity and sorority members were…

  13. Let My Country Awake. The Human Role in Development: Thoughts on the Next Ten Years.

    ERIC Educational Resources Information Center

    Adiseshiah, Malcolm S.

    This book is divided into four parts: (1) Development and the minds of men, (2) Development: alpha and omega, (3) The cross-roads, and (4) Unesco at work: three places, three functions and a state of mind. Development theory and practice involves evaluation and judgment on the good society, on the good life for men and nations. In its broadest…

  14. Analysis of Health Data from Ten Years of Polaris Submarine Patrols

    DTIC Science & Technology

    1979-01-01

    en revanche, ceux-la ont signale moiro de maladies - genito-urinaires, systemiques (infections et mononucleose ci-inclus), craniennes, et...classifications suivantes est diminuee: respiratoire, otorhinolaryngologique, gastro-tntestinaux, cardiovasculaire ,. urologique, et general (qui comprend

  15. The Process of Developing and Implementing the Ten-Year Educational Development Programme

    ERIC Educational Resources Information Center

    Doucoure, Samba; Diarra, Abou

    2006-01-01

    Mali, in choosing democratic education within a decentralised context, has made a clear choice as to the importance of the role that communities and territorial collectivities should play in the profound change and reform of the educational system. This reform will only happen if the communities, territorial collectivities, and all the actors…

  16. Evaluation of Hotel, Restaurant, and Institutional Management Graduates: A Ten Year Review.

    ERIC Educational Resources Information Center

    Johnson, Dona, Comp.; And Others

    A study of graduates from the Hotel, Restaurant, and Institutional Management program at St. Louis Community College at Forest Park was conducted, primarily in order to elicit information from graduates regarding potentially effective recruitment methods for minority groups and women. The study also sought to obtain evaluation of course curriculum…

  17. [Benefit of a geriatric mobile team in the emergency departments: a ten-year review].

    PubMed

    Natali, Jean-Philippe; Schwald, Nathalie; Bach, Frédérique; Bourgouin, Gaëlle; Chiffray, Dominique; Bloch, Frédéric

    2015-01-01

    A geriatric mobile team was created in the emergency department of Cochin Hospital in Paris, in 2005. This key player in the multi-disciplinary management of elderly patients in the emergency department and in the geriatric care pathway, showed, during its 10-year of existence, its utility.

  18. A core curriculum for international health: evaluating ten years' experience at the University of Arizona.

    PubMed

    Pust, R E; Moher, S P

    1992-02-01

    215 graduates (118 women and 97 men) of the University of Arizona's International Health Core Curriculum received a questionnaire after completion of their clinical practice in order to evaluate the experience of 10 years from 1982-91. The curriculum consisted of a 3- week orientation course given to 4th year medical students with core contents of population, nutrition, and infectious diseases followed up by student evaluation upon completion. 192 students were eligible for the survey of whom 154 completed it yielding an 80% response rate: 139 future physicians and 15 nurses, health educators, and nutritionists. 113 of 154 respondents completed an international health field experience after the course in 43 developing countries: 22% in Africa, 39% in Asia-Pacific, and 39% in Latin American-Caribbean. 79% were in rural and 34% in urban areas. A public health-community medicine program was incorporated in the clinical work at most sites. 95% of them participated in clinical care, 73% in community teaching, and 51% in research and evaluation. The duration of this field experience lasted 6-12 months for 69% of them. The median responses regarding the possibility of postcourse international field work and rating the worth of the course for clinical care, teaching others, and research were well or very well. They also rated the preparation of the course for subsequent work at 43 specific sites as good and dealing with limited resources and cross-culture communication as very good. All were willing to recommend the course to their peers.

  19. Ten years of RELEA: Achievements and challenges for astronomy education development

    NASA Astrophysics Data System (ADS)

    Bretones, P. S.; Jafelice, L. C.; Horvath, J. E.

    2016-10-01

    When an area of education, and more particularly the research within this area, is aimed to development, one of the basic requirements is the existence of a regular publication that accounts for the scientific production in that area. This study aims to analyze 10 years of Latin-American Journal of Astronomy Education (RELEA) [http://www.relea.ufscar.br/].

  20. Ten Years of Spatial Disorientation in U.S. Army Rotary-Wing Operations (Reprint)

    DTIC Science & Technology

    2012-10-01

    of the time, and changes over time in training, tactics, and technol- ogy [e.g., night vision goggles (NVG) and forward look- ing infrared (FLIR... night vision systems]. Ogden and colleagues ( 21 ) provided one of the fi rst looks (1957 to 1963) at Army helicopter “ orientation error ” (OE), re... vision goggles ; NVS- night vision system; OIF- Operation Iraqi Freedom; OEF- Operation Enduring Freedom. Fig. 1. Spatial disorientation-related

  1. Ten Years after a Preschool Intervention for Low Birth Weight Spanish-American Children.

    ERIC Educational Resources Information Center

    Askins, Billy E.; Cornett, Joe D.

    1985-01-01

    The low birth weight criterion and other factors used for entry in 1971 into the Responsive Environment Program for Spanish-American Children (RESPAC), yielded predictions of school failure for nearly all RESPAC students. A significant finding of the 10-year follow-up study was that 86 percent of RESPAC students had normal school progress. (JHZ)

  2. Ten years of maintaining and expanding a microbial genome and metagenome analysis system.

    PubMed

    Markowitz, Victor M; Chen, I-Min A; Chu, Ken; Pati, Amrita; Ivanova, Natalia N; Kyrpides, Nikos C

    2015-11-01

    Launched in March 2005, the Integrated Microbial Genomes (IMG) system is a comprehensive data management system that supports multidimensional comparative analysis of genomic data. At the core of the IMG system is a data warehouse that contains genome and metagenome datasets sequenced at the Joint Genome Institute or provided by scientific users, as well as public genome datasets available at the National Center for Biotechnology Information Genbank sequence data archive. Genomes and metagenome datasets are processed using IMG's microbial genome and metagenome sequence data processing pipelines and are integrated into the data warehouse using IMG's data integration toolkits. Microbial genome and metagenome application specific data marts and user interfaces provide access to different subsets of IMG's data and analysis toolkits. This review article revisits IMG's original aims, highlights key milestones reached by the system during the past 10 years, and discusses the main challenges faced by a rapidly expanding system, in particular the complexity of maintaining such a system in an academic setting with limited budgets and computing and data management infrastructure.

  3. Ten-Year Trends in Public Opinion from the "EDNEXT" Poll

    ERIC Educational Resources Information Center

    Peterson, Paul E.; Henderson, Michael B.; West, Martin R.; Barrows, Samuel

    2017-01-01

    The year 2016 marks the 10th anniversary of the "Education Next" poll on K-12 education policy, offering "Education Next" the opportunity to take a retrospective look at public opinion on this vital topic. In 8 of the past 10 years, "Education Next" has also surveyed teachers on the subject and has seen some…

  4. Western Perceptions of Hong Kong Ten Years on: A Corpus-Driven Critical Discourse Study

    ERIC Educational Resources Information Center

    Cheng, Winnie; Lam, Phoenix W. Y.

    2013-01-01

    This article studies the Western perceptions of and relations with Hong Kong a decade after the reversion of the sovereignty from Britain to China in 1997. Previous studies have demonstrated that the West had a significantly negative view on the future of Hong Kong with respect to the handover. According to recent observations, however, the…

  5. The Spiral of Silence Ten Years Later: An Examination and Evaluation.

    ERIC Educational Resources Information Center

    Salmon, Charles T.; Kline, F. Gerald

    In her model of opinion formation, Elizabeth Noelle-Neumann postulates a spiral of silence: to avoid isolation, people holding minority views either alter their ideas to conform to the majority's stance or remain silent, thus increasing the impression of the majority view's dominance. While providing a helpful integration of disparate ideas in…

  6. Celebrating Ten Years. Foundation for Individual Rights in Education Annual Report, 2009

    ERIC Educational Resources Information Center

    Foundation for Individual Rights in Education (NJ1), 2009

    2009-01-01

    This paper presents the annual report of the Foundation for Individual Rights in Education (FIRE) for 2009. The year 2009 was momentous for FIRE, for it marked its tenth anniversary. In the last decade, FIRE has been remarkably successful at fighting to secure basic rights of free speech and conscience on college campuses. It has fought for…

  7. Ten years of a multidisciplinary diabetic foot team approach in Sao Paulo, Brazil

    PubMed Central

    Batista, Fábio; Augusto Magalhães, Antonio; Gamba, Mônica; Nery, Caio; Cardoso, Cristina

    2010-01-01

    Diabetes mellitus can cause devastating foot problems including loss of protective sensation with subsequent ulcerations and amputations. The natural history and pathophysiology of diabetic foot ulcers is best understood and managed by a multiprofessional team approach. The main factors for prevention and treatment of these devastating diabetic foot conditions are shown, with special attention to education of the patient. This approach decreases the morbidity of the disease, besides its economical and social feasibility. PMID:22396805

  8. Bologna at the Finish Line: An Account of Ten Years of European Higher Education Reform

    ERIC Educational Resources Information Center

    Bartolo, Daniela; Bjerke, Christian Hemmestad; Blattler, Andrea; Deca, Ligia; Gielis, Inge; Karlsson, Solvi; Nielsen, Kristine Bak; Pall, Allan; Rytkonen, Petri; Santa, Robert; Szabo, Melinda

    2010-01-01

    The European Students' Union (ESU) has been writing about the student perspective on the Bologna Process since it get formally involved in it. Four editions of the students' independent stocktaking report "Bologna With Student Eyes" between 2003 and 2009 shed light on the perception of those stakeholders, which are probably mostly…

  9. Ten Years of Reform in Primary Mathematics Education in England a Review of Effectiveness

    DTIC Science & Technology

    2008-01-01

    W. and Deakin Crick , R., 2002, A systematic review of the impact of summative assessment and tests on students’ motivation for learning, Research...pp. 32–48). New York, NY: Routledge/Taylor and Francis . Wood, T. 1999, ‘Creating a context for argument in mathematics class.’ Journal for Research

  10. Ten years of genetics and genomics: what have we achieved and where are we heading?

    PubMed Central

    Heard, Edith; Tishkoff, Sarah; Todd, John A.; Vidal, Marc; Wagner, Günter P.; Wang, Jun; Weigel, Detlef; Young, Richard

    2010-01-01

    To celebrate the first 10 years of Nature Reviews Genetics, we asked eight leading researchers for their views on the key developments in genetics and genomics in the past decade and the prospects for the future. Their responses highlight the incredible changes that the field has seen, from the explosion of genomic data and the many possibilities it has opened up to the ability to reprogramme adult cells to pluripotency. The way ahead looks similarly exciting as we address questions such as how cells function as systems and how complex interactions among genetics, epigenetics and the environment combine to shape phenotypes. PMID:20820184

  11. Ten Year Plan for the Redevelopment of Intellectual Disability Services: Consumers' Guide. Final Report.

    ERIC Educational Resources Information Center

    Neilson Associates Pty. Ltd., Melbourne (Australia).

    This consumers' guide provides an easily understandable, large print summary of the recommendations in a 10-year plan for changes in services to people with intellectual disabilities in Victoria, Australia. Twenty of the 250 recommendations of the plan are given in simplified language accompanied by illustrations, including recommendations for:…

  12. Ten Years of Monitoring the Eruption of Shrub Mud Volcano, Alaska

    NASA Astrophysics Data System (ADS)

    McGimsey, R. G.; Evans, W. C.; Bergfeld, D.; McCarthy, S. H.; Hagstrum, J. T.

    2007-12-01

    Shrub mud volcano, one of three in the Klawasi group on the eastern flank of Mount Drum volcano in the Wrangell volcanic field of eastern Alaska, has been erupting warm, saline mud and CO2-rich gas continuously since at least the summer of 1997, following 40 years of repose. The initial eruption in early summer of 1997, documented by Richter and others (1998), involved violent fountaining of mud, up to 6-8 m high, from nearly a dozen vents located near the summit, and quiet effusion from vents located about mid-way down the north flank of the 100-m-high cone. Guided by topography, early emissions of copious amounts of CO2 gas flowed in narrow streams through brushy foliage leaving behind stripes of brown, dead vegetation along the flow paths. The hazard posed by the CO2 emissions was evident from dead birds and mammals found near the vents. Initial surveys of the activity in 1997 recorded water temperatures up to 46°C. A survey in 1999 by Sorey and others (2000) found numerous active vents-many in different locations than those two years earlier-a maximum water temperature of 54°C, and an estimated total discharge of warm water of 50 l/s. Measured CO2 emissions were extrapolated to a discharge rate of 6-12 tonnes/day. The highest water temperature recorded was 57.3°C in 2000, with temperatures gradually declining since. From year to year, we found that eruptive activity migrated amongst clusters of vents, some new and some continuing from 1997. Between the summer of 2003 and the spring of 2004, the system changed dramatically when a large collapse pit formed a few tens of meters from the main summit vents and all previously active vents became inactive. This water-filled circular pit measured 28 m in diameter, up to 9 m deep, and encompassed an area that had previously been unaffected by the eruptive activity. In July 2004, water temperature and discharge at the outlet channel was 37.2°C and 9.4 l/s, respectively. The total CO2 discharge from the roiling pool was 140 l/s (about 20 tonnes/day), and the diffuse efflux (0.13 tonnes/day) was comparable to the 0.23 tonnes/day measured in 1999. Based on discharge and δ13C values of the gas and water phases (-4.6‰ and +1.35‰, respectively) carbon in the reservoir was calculated to be -3.1‰, supporting a mixed magmatic and limestone source for the CO2. Deep pits exposed during the current eruption have provided clues to the possible origin of Shrub, the largest, and highest mud volcano of the Klawasi group. Shrub stands about 100 m high and is an oblong cone in shape. Cross-sections of the material composing the cone reveal a chaotic pile of debris ranging from clay to boulders (angular to subrounded, up to 1.5 m across), the latter too large to have been rafted up by mud and gas venting. Pleistocene glaciers extending into the Copper River Valley from Mount Drum covered the area currently occupied by Shrub. We hypothesize that as the glaciers stagnated and began to retreat, subglacial melting caused by the rising warm mud formed an anomalous moulin that became the receptacle for rock and sediment debris washed in from supraglacier runoff. Thus the constructional form of Shrub is likely a moulin kame.

  13. Alternatives to Custody: A Ten-Year Review of a Community-Based Program in Britain.

    ERIC Educational Resources Information Center

    Stevens, Barbara Christine

    1996-01-01

    Describes the development of a community forensic psychology service during its first 10 years of service. Service emphasizes cooperation among psychologists, probation officers, and others in establishing alternatives to custody for sex offenders, shoplifters, drug and alcohol abusers, and young criminals. Discusses theoretical orientation of the…

  14. Intrascrotal lipoblastoma in a ten year old: case report and review of literature

    PubMed Central

    Nakib, Ghassan; Calcaterra, Valeria; Avolio, Luigi; Guazzotti, Marinella; Goruppi, Ilaria; Viglio, Alessandra; Pelizzo, Gloria

    2013-01-01

    Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature. PMID:23772297

  15. [Annual change of the pet in allergic patients home for ten years].

    PubMed

    Maeda, Y; Kudoh, M; Tomita, S; Hasegawa, M; Akiyama, K

    1999-01-01

    There are only few paper in Japan which reports the prevalence of pet keepers in the allergic population and also of the type of pets they keep. We made investigation on these points in 1337 allergic patients employing a questionnaire. Among 1337 patients, allergic conjunctivitis patients were found in 67, eczema patients in 118, allergic rhinitis patients in 368 and bronchial asthmatic patients in 1043. These number contained those who overlapped in symptoms. Approximately 43% of allergy patients are currently keeping the pet at present while 11.2% of the patient had kept the pet in the past. There were two peaks in the age when they began to keep a pet, 6 to 12 and 30 to 40 years of age. Trend in the past decade showed that both the dog and cat bred in foreign countries were increasing. About 80% of patients who own the foreign bred dogs keep them indoor. This ratio is increasing gradually. Another conspicuous change is the sharp increase in those who keep hamsters which occupied 20% of all the pet keeper in 1997. Percentages of the patient who recognizes the aggravation of their symptoms in eye, nose, skin and also as asthma often pet keeping is a about 10%. One out of 4 patients who keep the pet has a family member with rhinitis and/or asthma. We concluded that too many of the allergic patients keep the pet against their benefit and they must be informed that the pet could be the cause of allergy symptoms.

  16. Ten-Year Climatology of Summertime Diurnal Rainfall Rate Over the Conterminous U.S.

    NASA Technical Reports Server (NTRS)

    Matsui, Toshihisa; Mocko, David; Lee, Myong-In; Tao, Wei-Kuo; Suarez, Max J.; Pielke, Roger A., Sr.

    2010-01-01

    Diurnal cycles of summertime rainfall rates are examined over the conterminous United States, using radar-gauge assimilated hourly rainfall data. As in earlier studies, rainfall diurnal composites show a well-defined region of rainfall propagation over the Great Plains and an afternoon maximum area over the south and eastern portion of the United States. Zonal phase speeds of rainfall in three different small domains are estimated, and rainfall propagation speeds are compared with background zonal wind speeds. Unique rainfall propagation speeds in three different regions can be explained by the evolution of latent-heat theory linked to the convective available potential energy, than by gust-front induced or gravity wave propagation mechanisms.

  17. The School of Pharmacy Geneva-Lausanne (EPGL) - the first ten years.

    PubMed

    Borchard, Gerrit; Carrupt, Pierre-Alain

    2012-01-01

    With the creation of the School of Pharmacy Geneva-Lausanne (EPGL) in 2003, cantons Geneva and Vaud pooled their resources with the objective of reinforcing the research and teaching in the pharmaceutical sciences. Its core research units cover all aspects of fundamental pharmaceutical research and include collaborative research with the University Hospitals of Geneva and Lausanne.

  18. Ten years of the Three Gorges Dam: a call for policy overhaul

    NASA Astrophysics Data System (ADS)

    Yang, Xiankun; Lu, X. X.

    2013-12-01

    The Three Gorges Dam (TGD), the world’s largest source of ‘clean’ hydroelectric power (Shen and Xie 2004), has entered its tenth year after the first turbine went into operation in June 2003. The dam, with a generating capacity 20 times that of the United States’ Hoover Dam, has been hailed as a crucial part of a solution to China’s energy crisis. Despite great benefits, however, major concerns have been voiced over the disastrous environmental and social consequences of this massive engineering project (Stone 2011). In this paper, we review the benefits and impacts learned from the controversial megadam over the past decade and discuss perspective quests on policy overhaul for future environmental protection.

  19. Social Marking and Conceptual Change: The Conception of Light for Ten-Year Old Children.

    ERIC Educational Resources Information Center

    Ravanis, Konstantinos; Papamichael, Yannis; Koulaidis, Vasilis

    2002-01-01

    Investigates the role that social mediation plays in the destabilization of preconceptions of the concept of light among primary school pupils. One experimental group participated in a teaching process which aimed to lead students to cognitive conflict. Another group was taught with traditional methods. Differences between groups in pre- and…

  20. Nuclear Society of Russia: Ten years in the world nuclear community

    SciTech Connect

    Ponomarev-Stepnoi, N.N.; Gagarinski, A.Yu.

    2000-07-01

    A nuclear society, which is a nongovernmental organization of nuclear professionals, appeared in the Soviet Union at the end of the 1980s--when social conditions for such a society had matured. Deep changes in the entire country's social consciousness had promoted the specialists understanding of the need to unite in order to overcome the nuclear community's dissociation, the monopoly of the nuclear ministry, and the secrecy syndrome of all nuclear issues. The new public association announced the guiding principles of its activities to be openness and glasnost and completeness and truthfulness of information supplied to decision makers and to the society as a whole. Important to the information system of the NSR are topical meetings and seminars on quite varied but always actual problems of nuclear energy use, often with foreign participation. The variety of these NSR meeting subjects is illustrated by the titles of several meetings of the last 2 yr: Safety Culture in Nuclear Power, Youth and the Plutonium Challenge, Nuclear Fuel for Mankind, Nuclear Power in Space, Radiation Legacy of the Former-USSR, the Murmansk International Forum Nuclear Fleet and Ecology, and many others. A special place among NSR seminars belongs to the annual meeting, Nuclear Energy and Public Opinion, the Russian analog of the European PIME conference. Starting from distribution of ENS periodicals--the Nuclear Europe Worldscan magazine and Nucleus information sheet--among its members, the NSR soon began publishing its own Informational Bulletin (since 1989). Note that in the first years of the Nuclear Society's existence, it has been possible to publish periodicals, conference proceedings, and even books in English. Unfortunately, financial difficulties of the last years have frozen this most useful activity, which the NSR, however, hopes to resume. In the last period, the materials of the international information agency NucNet, which provides both regular information for the analysis of nuclear energy production trends and--most importantly for relations with the mass media and the public--crisis information (latest examples: Tokaimura, the virtual Y2K crisis, etc.), have become important sources of information for the NSR. It should be emphasized that the financial participation of the Russian Minatom (maintained at the insistent request of the NSR) in the NucNet system provides sufficiently wide dissemination of operative nuclear information not only through the NSR headquarters but also via its regional branches and separate enterprises. From its side, NSR has assumed the responsibility for the adequate flow of information on Russian nuclear events to NucNet. As a living and developing organism, the NSR wants to respond to its time's challenges. Several prospective directions could be among the NSR information exchange plans: (1) Independent international analysis of the problems of the use of nuclear energy, which is presently in a stagnation period but with future large-scale development, is as possible today as it never had been before. (2) In the field of public relations, many achievements of Russian and US specialists (in the form of articles, analyzing nuclear energy on the popular and highly professional level) stay inaccessible to others because of the language barrier. A possible joint ANS/NSR project on selection, translation, and exchange of such materials, with their further wide publication, represents an obvious reserve in their societies' information activities. (3) The International Youth Nuclear Congress project (proposed by the Russian nuclear youth and supported by ANS and ENS), conceived as a bridge between generations and a forum for opinion exchange between young nuclear specialists from various countries, deserves further development and appropriation of permanent status in the activities of the world nuclear societies.

  1. Ten years of barcoding at the African Centre for DNA barcoding.

    PubMed

    Bezeng, Simeon Bezeng; Davies, T Jonathan; Daru, Barnabas H; Kabongo, Ronny Mukala; Maurin, Olivier; Yessoufou, Kowiyou; van der Bank, Herman; Van der Bank, Michelle

    2017-03-24

    The African Centre for DNA Barcoding (ACDB) was established in 2005 as part of a global initiative to accurately and rapidly survey biodiversity using short DNA sequences. The mitochondrial cytochrome c oxidase 1 gene (CO1) was rapidly adopted as the de facto barcode for animals. Following the evaluation of several candidate loci for plants, the Plant Working Group of the Consortium for the Barcoding of Life in 2009 recommended that the two plastid genes, rbcLa and matK, be adopted as core DNA barcodes for terrestrial plants. To date, numerous studies continue to test the discriminatory power of these markers across various plant lineages. Over the past decade, we at the African Centre for DNA Barcoding, have used these core DNA barcodes to generate a barcode library for southern Africa. To date, the ACDB has contributed more than 21 000 plant barcodes and over 3 000 CO1 barcodes for animals to the Barcode of Life Database (BOLD). Building upon this effort, we at the ACDB have addressed questions related to community assembly, biogeography, phylogenetic diversification, and invasion biology. Collectively, our work demonstrates the diverse applications of DNA barcoding in ecology, systematics, evolutionary biology, and conservation.

  2. Ten-year changes in breast cancer knowledge, attitudes, and practices in Native Hawaiian women.

    PubMed

    Tsark, J U; Braun, K L

    2001-09-01

    Compared to women in other ethnic groups, Native Hawaiian women have the highest breast cancer mortality rates in the state of Hawai'i. Nationally, the five-year relative survival rate for Native Hawaiian women is 9% shorter than for Caucasians and all races. This poor outcome has been attributed, in part, to late-stage detection of cancer in Native Hawaiians, and data suggest that breast cancer screening rates for Native Hawaiian women are relatively low. This study examined breast cancer knowledge, attitudes, and practices (KAP) among Native Hawaiian women, reached through their friendship, community, and organizational networks. Response to an initial KAP survey in 1989-1990 was rewarded by a voucher for a free mammogram. Participation in both the survey (n = 903) and mammogram offer (n = 496) was high. The initial, Time 1 participants were resurveyed in 1999-2000, yielding a sample of 117 women who completed KAP surveys at both time points. After 10 years, changes in women's knowledge and attitudes were minimal. However, remarkable improvements in breast health practices were seen, with 62% of women reporting compliance with American Cancer Society guidelines for mammogram screening in 1999-2000, compared to only 14% in 1989-1990. Findings suggest that breast health practices can be improved through appropriate outreach; encouragement by health professionals; and policies and programs that increase access and affordability.

  3. Ten years of R&D and full automation in molecular diagnosis.

    PubMed

    Greub, Gilbert; Sahli, Roland; Brouillet, René; Jaton, Katia

    2016-01-01

    A 10-year experience of our automated molecular diagnostic platform that carries out 91 different real-time PCR is described. Progresses and future perspectives in molecular diagnostic microbiology are reviewed: why automation is important; how our platform was implemented; how homemade PCRs were developed; the advantages/disadvantages of homemade PCRs, including the critical aspects of troubleshooting and the need to further reduce the turnaround time for specific samples, at least for defined clinical settings such as emergencies. The future of molecular diagnosis depends on automation, and in a novel perspective, it is time now to fully acknowledge the true contribution of molecular diagnostic and to reconsider the indication for PCR, by also using these tests as first-line assays.

  4. A Ten Year Follow-up of Attitudes toward Evaluation in Behavioral Aspects of Clinical Practice.

    ERIC Educational Resources Information Center

    Grace, Edward G.; Cohen, Leonard A.

    1991-01-01

    Repetition of a 1979 survey of University of Maryland at Baltimore dental school students (n=258) and faculty (n=120) concerning student evaluation in behavioral science content found more favorable student responses, little change in faculty attitudes toward the importance of behavioral sciences, and more interest in evaluating students on…

  5. Generation IV Nuclear Energy Systems Ten-Year Program Plan Fiscal Year 2005, Volume 1

    SciTech Connect

    2005-03-01

    As reflected in the U.S. ''National Energy Policy'', nuclear energy has a strong role to play in satisfying our nation's future energy security and environmental quality needs. The desirable environmental, economic, and sustainability attributes of nuclear energy give it a cornerstone position, not only in the U.S. energy portfolio, but also in the world's future energy portfolio. Accordingly, on September 20, 2002, U.S. Energy Secretary Spencer Abraham announced that, ''The United States and nine other countries have agreed to develop six Generation IV nuclear energy concepts''. The Secretary also noted that the systems are expected to ''represent significant advances in economics, safety, reliability, proliferation resistance, and waste minimization''. The six systems and their broad, worldwide research and development (R&D) needs are described in ''A Technology Roadmap for Generation IV Nuclear Energy Systems'' (hereafter referred to as the Generation IV Roadmap). The first 10 years of required U.S. R&D contributions to achieve the goals described in the Generation IV Roadmap are outlined in this Program Plan.

  6. Self-Report Stability of Adolescent Cigarette Use across Ten Years of Panel Study Data

    ERIC Educational Resources Information Center

    Shillington, Audrey M.; Reed, Mark B.; Clapp, John D.

    2010-01-01

    This study is the first to examine adolescent cigarette report stability over 10 years. Six waves of data were utilized from the National Longitudinal Survey of Youth. This study examined internal/logical consistency and external consistency. Report stability was higher for lifetime use reports than the age of onset reports. Wave-by-wave…

  7. Ten years of industrial and municipal membrane bioreactor (MBR) systems - lessons from the field.

    PubMed

    Larrea, Asun; Rambor, Andre; Fabiyi, Malcolm

    2014-01-01

    The use of membrane bioreactors (MBRs) in activated sludge wastewater treatment has grown significantly in the last decade. While there is growing awareness and knowledge about the application of MBR technology in municipal wastewater treatment, not much information is available on the application of MBRs in industrial wastewater treatment. A comparative study of design data, operating conditions and the major challenges associated with MBR operations in 24 MBR plants treating both municipal and industrial wastewater, built by and/or operated by Praxair, Inc., is presented. Of the 24 MBR systems described, 12 of the plants used high purity oxygen (HPO). By enabling a wide range of food/microorganism ratios and loading conditions in the same system, HPO MBR systems can extend the options available to industrial plant operators to meet the challenges of wide fluctuations in organic loading and footprint limitations. While fouling in industrial MBR systems can be an issue, adequate flux and permeability values can be reliably maintained by the use of good maintenance strategies and effective process controls (pretreatment, cleaning and membrane autopsies).

  8. Ten Years Development of Metallurgical Research and Technology in Communist China

    DTIC Science & Technology

    1960-01-15

    ratio was lowe., red 15.7"(, Th, .ýx-pri3ncea on blast furnace operations since tho laco foiv~ard shows that as tha smelting intinsity is raised the air...combination with flotation, and reverse flotation. In each process , the iron concentrate made contains 60 Fe or better, recovery is more than 80", and...metallurgical practice. Therefore, a whole series of metallurgical tests must be made in large industrial scale blast furnaces. Blast furnace tests indicate

  9. Cassini-Huygens Science Highlights: Ten years of Surprises in the Saturn System

    NASA Astrophysics Data System (ADS)

    Spilker, Linda; Esposito, Larry W.; Matson, Dennis L.; Edgington, Scott; Altobelli, Nicolas

    The Cassini-Huygens mission has greatly enhanced our understanding of the Saturn system. Fundamental discoveries have altered our views of Saturn, its retinue of icy moons including Titan, the dynamic rings, and the system’s complex magnetosphere. Cassini has orbited Saturn for 10 years, delivering the Huygens probe to its Titan landing in 2005. It is now three years into its 7-year Solstice mission, returning science in a previously unobserved seasonal phase. As it watches the approach of northern summer, long-dark regions throughout the system become sunlit, allowing Cassini’s science instruments to probe as-yet unsolved mysteries. Key Cassini-Huygens discoveries include icy jets of material streaming from tiny Enceladus’ south pole, lakes of liquid hydrocarbons and methane rain on giant Titan, three-dimensional structures in Saturn’s rings, and curtain-like aurorae flickering over Saturn’s poles. The Huygens probe sent back amazing images of Titan’s surface, and made detailed measurements of the atmospheric composition, structure and winds. Key Cassini-Huygens science highlights will be presented. The Solstice Mission continues to provide new science as Cassini observes seasonal and temporal changes, and addresses new questions that have arisen during the mission thus far. The mission’s grand finale occurs in 2017, with 22 inclined orbits between the innermost D ring and the upper portions of Saturn’s atmosphere, enabling unique gravity and magnetic field measurements of the planet, unprecedented determination of the ring mass, some of the highest resolution measurements of the rings and Saturn, and in situ observations in a completely new region around the planet. Cassini-Huygens is a cooperative undertaking by NASA, the European Space Agency (ESA), and the Italian space agency (Agenzia Spaziale Italiana, ASI). This work was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. Copyright 2014 California Institute of Technology. Government sponsorship is acknowledged.

  10. Ten years of Cassini Discoveries in the Saturn System and More Excitement to Come

    NASA Astrophysics Data System (ADS)

    Spilker, Linda J.; Edgington, Scott; Altobelli, Nicolas

    2014-11-01

    Cassini’s findings have revolutionized our understanding of Saturn, its complex rings, the amazing assortment of moons and the planet’s dynamic magnetic environment. The robotic spacecraft arrived in 2004 after a 7-year flight from Earth, dropped a parachuted probe named Huygens to study the atmosphere and surface of Saturn’s big moon Titan, and commenced making astonishing discoveries that continue today. Icy jets shoot from the tiny moon Enceladus; Titan’s hydrocarbon lakes and seas are dominated by liquid ethane and methane, and complex pre-biotic chemicals form in the atmosphere and rain to the surface; 3-dimensional structures rise above Saturn’s rings, and a giant Saturn storm circled the entire planet. Cassini’s findings at Saturn have also fundamentally altered many of our concepts of how planets form around stars. The Solstice Mission continues to provide fundamental new science as Cassini observes seasonal and temporal changes, and addresses new questions that have arisen during the mission thus far. Cassini is now 4 years into its 7-year Solstice Mission. The mission’s grand finale occurs in 2017, with 22 inclined orbits between the innermost D ring and the upper portions of Saturn’s atmosphere, enabling unique gravity and magnetic field measurements of the planet, unprecedented determination of the ring mass, some of the highest resolution measurements of the rings and Saturn, and in situ observations in a completely new region around the planet. Highlights from 10 years of Cassini’s ambitious inquiry at Saturn will be presented along with the remarkable science that will be collected in the next three years.Cassini-Huygens is a cooperative undertaking by NASA, the European Space Agency (ESA), and the Italian space agency (Agenzia Spaziale Italiana, ASI).This work was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under contract with NASA. Copyright 2014 California Institute of Technology. Government sponsorship is acknowledged.

  11. Ten year outcomes of outpatients with schizophrenia on conventional depot antipsychotics: a systematic chart review.

    PubMed

    Uchida, Takahito; Suzuki, Takefumi; Sakurai, Hitoshi; Tsutsumi, Chisa; Den, Ryosuke; Mimura, Masaru; Uchida, Hiroyuki

    2013-09-01

    Long-term follow-up data of patients with schizophrenia on depot antipsychotics have been few and the longest follow-up period has been up to 7 years. We carried out a systematic chart review to examine 10-year outcomes for outpatients with schizophrenia who were receiving a conventional depot antipsychotic. Maintenance of outpatient status for 10 years was considered as a favorable outcome. From the initial sample of 1587 outpatients, 90 patients who were receiving a depot antipsychotic were included in this study (mean±SD, age 44.0±13.0 years; men, N=54). Haloperidol decanoate, fluphenazine decanoate, fluphenazine enanthate, and haloperidol decanoate plus fluphenazine enanthate were used in 53 (58.9%), 29 (32.2%), seven (7.8%), and one (1.1%) patients, respectively. These depot antipsychotics accounted for 36.9% of the total antipsychotic dosage on average. Seventeen patients (18.9%) successfully maintained outpatient status for 10 years. The most frequent reason for dropout was 'hospitalization' (N=49, 54.4%), followed by 'referral to another clinic/hospital' (N=9, 10.0%) and 'side effects' (N=7, 7.8%). As only 36.9% of the chlorpromazine equivalents were administered through depot antipsychotics, it is difficult to draw any firm conclusion. Still, the data suggest that even depot antipsychotics may not sufficiently prevent relapse in the treatment of schizophrenia.

  12. Unburying Patriotism: Critical Lessons in Civics and Leadership Ten Years Later

    ERIC Educational Resources Information Center

    Osanloo, Azadeh F.

    2011-01-01

    This manuscript provides a historical and pedagogical framework for American educational and sociopolitical responses after national tragedies (e.g., Pearl Harbor, 9/11). Moreover, this research explores the overt xenophobic and ethnocentric tendencies (exacerbated by media forums) after these events, which triggered resurgence in a sort of…

  13. A ten-year experience of physical Intimate partner violence (IPV) in a French forensic unit.

    PubMed

    Savall, Frédéric; Lechevalier, Agathe; Hérin, Fabrice; Vergnault, Marion; Telmon, Norbert; Bartoli, Christophe

    2017-02-01

    Forensic units have a central role to play in healthy public policy, by the collection and management of violence. This study aims to describe the characteristics of physical Intimate Partner Violence (IPV) against men reported over 10 years in the forensic unit of Toulouse (France) and to compare them with the characteristics of physical IPV against women over the same period. All the medico-legal reports of male victims over 18 years of age between 2005 and 2014 were analyzed. Female victims over 18 years of age in the same period were randomized by year in order to study a similar number of individuals. We analyzed 712 forensic reports of male victims and 865 forensic reports of female victims. Repeated consultation concerned 20.5% of women and 7.5% of men (p < 0.001). More male victims than female victims consulted in an emergency unit (p < 0.001). The most frequently alleged manner of attack was punching for male victims (34.1%) and grabbing or pushing for female victims (86.7%). There were fewer wounds and vascular or visceral injuries for female victims (p = 0.001). There were more reports of no injury for female victims (p < 0.001) and fewer reports with at least two injuries (p = 0.002). The most common injuries were superficial skin injuries (abrasion, bruise or hematoma) for both groups. On the one hand, physical IPV against women was more frequent than against men, while physical IPV against men seemed to be more severe than against women. The distribution of alleged manners of attack and injuries were consistent with previous studies. However, the mechanisms of the origin of the process of violence are difficult to apprehend in such a dyadic context. The findings should be interpreted with caution, but they provide original and substantial material, which can be useful in recognizing victims and in developing preventive strategies. With this aim, forensic units have a central role to play in the collection of violence and in individualized management. In France, this subject has not been extensively studied and future research is needed to emphasize the characteristics of IPV in order to better understand the phenomenon and to create and assess public policies in order to prevent it.

  14. Ten-year air sample analysis of Aspergillus prevalence in a university hospital.

    PubMed

    Falvey, D G; Streifel, A J

    2007-09-01

    Airborne fungal samples were collected on a monthly basis for 10 years, from 1995 to 2005, at a tertiary university hospital. Paired samples were cultured at 25 and 37 degrees C. Data were interpreted according to the air filtration systems serving each location. Samples cultured at 37 degrees C from the patient care areas had a mean recovery of 18% of the mean recovery from outdoor air (22 versus 122cfu/m(3)). Recovery of Aspergillus spp. at 37 degrees C in the high-efficiency particulate air (HEPA)-filtered locations was positive for Aspergillus spp. approximately one-third of the time; the rest of the patient care areas were positive half of the time and the outdoor samples were positive 95% of the time. We found 48 sporadic bursts at 37 degrees C which produced counts >3 SD above the mean. Hospital-acquired infection was related to high recovery of Aspergillus fumigatus on at least one occasion. We have found it impossible, without implementing impractical measures, to provide an environment completely devoid of Aspergillus spp. We conclude that routine air sampling is not an effective means of predicting hospital-acquired infections. However, a transient spike, or burst, may be useful in identifying an in-house source of contamination and may be used to consider additional interventional treatments for patients at risk. Emphasis should be placed on maintaining high-efficiency filtration of the outside air and on ensuring that other environmental control methods are used to prevent dissemination of environmental opportunistic fungal spores.

  15. Overview of ten-year operation of the superconducting linear accelerator at the Spallation Neutron Source

    NASA Astrophysics Data System (ADS)

    Kim, S.-H.; Afanador, R.; Barnhart, D. L.; Crofford, M.; Degraff, B. D.; Doleans, M.; Galambos, J.; Gold, S. W.; Howell, M. P.; Mammosser, J.; McMahan, C. J.; Neustadt, T. S.; Peters, C.; Saunders, J. W.; Strong, W. H.; Vandygriff, D. J.; Vandygriff, D. M.

    2017-04-01

    The Spallation Neutron Source (SNS) has acquired extensive operational experience of a pulsed proton superconducting linear accelerator (SCL) as a user facility. Numerous lessons have been learned in its first 10 years operation to achieve a stable and reliable operation of the SCL. In this paper, an overview of the SNS SCL design, qualification of superconducting radio frequency (SRF) cavities and ancillary subsystems, an overview of the SNS cryogenic system, the SCL operation including SCL output energy history and downtime statistics, performance stability of the SRF cavities, efforts for SRF cavity performance recovery and improvement at the SNS, and maintenance activities for cryomodules are introduced.

  16. [Ten years of emergency attendances for cocaine-users in Spain].

    PubMed

    Galicia, Miguel; Nogué, Santiago; Burillo-Putze, Guillermo

    2014-10-07

    Cocaine is the second most consumed illegal drug in the western world, following cannabis. Since 1998, it is also the drug that more attendances generate in different emergency devices, and it is responsible for more of 60% of the emergencies directly related to drug consumption. This work reviews the main Spanish scientific articles published in the last 10 years, in which different factors related to the use of this drug have been analyzed in relation to the use of emergency by cocaine users. A total of 8,795 patients were included (interval 57-1,755), with an average age of 32.64 years (SD 3.02), and an average percentage of positives to cocaine of 54.78% (SD 47.03); there were 7 works with 100% of subjects being positive to cocaine. Males predominated with an average of 78.69% (SD 12). They presented cardiovascular symptoms in 30% cases (SD 22.7), neurological symptoms in 11.6% cases (SD 4.28) and psychiatric symptoms in 49.32% cases (SD 23.87). There was a multiple consumption in 49.02% of patients (interval 4.3-76.2), fundamentally associated with alcohol (57.78%, SD 6.18) and cannabis (21.56%, SD 10.72). Two hundred and forty-six patients (2.8%) needed admission and 8 died (0.09%).

  17. Permitting of Landfill Bioreactor Operations: Ten Years after the RD&D Rule

    EPA Science Inventory

    Prior to promulgation of the Rule, there were approximately 20 full-scale bioreactor projects in North America, including one in Canada. Of these, six were permitted by EPA (four Project XL sites and two projects listed separately under a cooperative research agreement at the Ou...

  18. Female Participation in ATE-Funded Programs: A Ten-Year Trend

    ERIC Educational Resources Information Center

    Westine, Carl D.; Gullickson, Arlen R.; Wingate, Lori A.

    2010-01-01

    It is widely known that women are generally underrepresented in STEM disciplines (science, technology, engineering, and mathematics). The National Science Foundation (NSF) Advanced Technological Education (ATE) program has persistently worked to reduce this disparity. For example, the 2000 solicitation specified "increasing the participation of…

  19. Ten year change in forest succession and composition measured by remote sensing

    NASA Technical Reports Server (NTRS)

    Hall, Forrest G.; Botkin, Daniel B.; Strebel, Donald E.; Woods, Kerry K.; Goetz, Scott J.

    1987-01-01

    Vegetation dynamics and changes in ecological patterns were measured by remote sensing over a 10 year period (1973 to 1983) for 148,406 landscape elements, covering more than 500 sq km in a protected forested wilderness. Quantitative measurements were made possible by methods to detect ecologically meaningful landscape units; these allowed measurement of ecological transition frequencies and calculation of expected recurrence times. Measured ecological transition frequencies reveal boreal forest wilderness as spatially heterogeneous and highly dynamic, with one-sixth of the area in clearings and early successional stages, consistent with recent postulates about the spatial and temporal patterns of natural ecosystems. Differences between managed forest areas and a protected wilderness allow assessment of different management regimes.

  20. A TEN-YEAR WATER BALANCE OF A MOUNTAINOUS SEMI-ARID WATERSHED. (R824784)

    EPA Science Inventory

    Quantifying water balance components, which is particularly challenging in snow-fed, semi-arid regions, is crucial to understanding the basic hydrology of a watershed. In this study, a water balance was computed using 10 years of data collected at the Upper Sheep Creek Water...