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Sample records for 2-2-dimethylpropane

  1. A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one.

    PubMed

    Demopoulos, Vassilis John; Nicolaou, Ioannis; Zika, Chariklia

    2003-01-01

    An effective synthesis of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one (4) was developed starting from 1H-indole (2). The key step involved suitable utilization of 4-(1-pyrrolidino)pyridine for the removal of the chloroacetyl moiety from chloroacetic acid 1-(2,2-dimethylpropionyl)-1H-indol-6-yl ester (3); a possible mechanism is, also, presented. Compound 4 might lead to selectively substituted derivatives, either on the phenolic-OH or the indolyl-NH, with putative biological interest. In this respect, we found that the core structure of 1H-indol-6-ol (1) possesses a degree of aldose reductase inhibitory potential, at a concentration of 100 microM. PMID:12520138

  2. Fragrance material review on 1-(2,4-dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one.

    PubMed

    Scognamiglio, J; Letizia, C S; Api, A M

    2013-12-01

    A toxicologic and dermatologic review of 1-(2,4-dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one when used as a fragrance ingredient is presented. 1-(2,4-Dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one is a member of the fragrance structural group Alkyl Cyclic Ketones. These fragrances can be described as being composed of an alkyl, R1, and various substituted and bicyclic saturated or unsaturated cyclic hydrocarbons, R2, in which one of the rings may include up to 12 carbons. Alternatively, R2 may be a carbon bridge of C2-C4 carbon chain length between the ketone and cyclic hydrocarbon. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for 1-(2,4-dimethyl-3-cyclohexenyl)-2,2-dimethylpropan-1-one were evaluated then summarized and includes physical properties, acute toxicity, skin irritation, sensitization, and genotoxicity data. A safety assessment of the entire Alkyl Cyclic Ketones will be published simultaneously with this document; please refer to Belsito et al. (Belsito, D., Bickers, D., Bruze, M., Calow, P., Dagli, M., Fryer, A.D., Greim, H., Miyachi, Y., Saurat, J.H., Sipes, I.G., 2013. A Toxicologic and Dermatologic Assessment of Alkyl Cyclic Ketones When Used as Fragrance Ingredients (submitted for publication)) for an overall assessment of the safe use of this material and all Alkyl Cyclic Ketones in fragrances.

  3. Design and structural studies of diimine/CdX2 (X = Cl, I) complexes based on 2,2-dimethyl-1,3-diaminopropane ligand

    NASA Astrophysics Data System (ADS)

    Warad, Ismail; Khan, Azmat Ali; Azam, Mohammad; Al-Resayes, Saud I.; Haddad, Salim F.

    2014-03-01

    Two related diimine Cd(II) complexes, [CdLCl2] 1 and [CdLI2] 2, derived from ligand, (N1Z,N3Z)-N1,N3-bis(2-chlorobenzylidene)-2,2-dimethylpropane-1,3-diamine, L were reported. The synthesized and isolated ligand and its Cd(II) complexes were characterized by elemental analyses, IR, 1H- and 13C NMR and UV/Vis spectroscopy, ESI-MS spectrometry, and TGA/DTG studies. Both the complexes were synthesized under similar synthetic procedures and structure of complex 2 was additionally determined by single crystal X-ray diffraction studies. The diimine ligand was coordinated to Cd(II) ion through two nitrogen atoms, and possessed distorted tetrahedral geometry. TGA and DTG studies of the complexes were carried out at 20-800 °C, and showed that the complexes were thermally stable and decomposed into three steps.

  4. Improved catalytic activity of homochiral dimeric cobalt-salen complex in hydrolytic kinetic resolution of terminal racemic epoxides.

    PubMed

    Kureshy, Rukhsana I; Singh, Surendra; Khan, Noor-Ul H; Abdi, Sayed H R; Ahmad, Irshad; Bhatt, Achyut; Jasra, Raksh V

    2005-11-01

    Enantiomerically pure epoxides (99%, ee) and diols (98%, ee) from racemic epichlorohydrin, 1,2-epoxypropane, 1,2-epoxyhexane, 1,2-epoxyoctane, and 1,2-epoxydodecane were obtained in 2-12 h by hydrolytic kinetic resolution (HKR) using the recyclable dimeric homochiral Co(III)-salen complex 1' (0.2 mol %) derived from 5,5-(2',2'-dimethylpropane)-di-[(R,R)-{N-(3-tert-butylsalicylidine)-N'-(3',5'-di-tert-butylsalicylidine)}-1,2-cyclohexanediamine] with cobalt(II) acetate. Unlike its monomeric version, the catalyst could be recycled several times without loss in performance. The use of BF(4) as counter ion in HKR reactions was also investigated.

  5. Phenoxy-bridged binuclear Zn(II) complex holding salen ligand: Synthesis and structural characterization

    NASA Astrophysics Data System (ADS)

    Azam, Mohammad; Al-Resayes, Saud I.

    2016-03-01

    A novel binuclear phenoxo-bridged zinc complex obtained from the interaction of ligand, 2,2-(1E,1E)-(2,2-dimethylpropane-1,3-diyl)bis(azanylylidene) bis(methanylylidene)diphenol with zinc chloride is reported. The synthesized and isolated zinc complex has been characterized by FT-IR, 1H- and 13C- NMR, ESI-MS, TGA/DTA and single crystal X-ray diffraction studies. The phenoxo-bridge in this binuclear Zn(II) complex is due to the phenolic oxygen of the salen liagnd. The complex crystallizes in monoclinic P-1 space group, and different geometry has been assigned for both zinc ions in the complex.

  6. Improving the efficiency of configurational-bias Monte Carlo: A density-guided method for generating bending angle trials for linear and branched molecules

    SciTech Connect

    Sepehri, Aliasghar; Loeffler, Troy D.; Chen, Bin

    2014-08-21

    A new method has been developed to generate bending angle trials to improve the acceptance rate and the speed of configurational-bias Monte Carlo. Whereas traditionally the trial geometries are generated from a uniform distribution, in this method we attempt to use the exact probability density function so that each geometry generated is likely to be accepted. In actual practice, due to the complexity of this probability density function, a numerical representation of this distribution function would be required. This numerical table can be generated a priori from the distribution function. This method has been tested on a united-atom model of alkanes including propane, 2-methylpropane, and 2,2-dimethylpropane, that are good representatives of both linear and branched molecules. It has been shown from these test cases that reasonable approximations can be made especially for the highly branched molecules to reduce drastically the dimensionality and correspondingly the amount of the tabulated data that is needed to be stored. Despite these approximations, the dependencies between the various geometrical variables can be still well considered, as evident from a nearly perfect acceptance rate achieved. For all cases, the bending angles were shown to be sampled correctly by this method with an acceptance rate of at least 96% for 2,2-dimethylpropane to more than 99% for propane. Since only one trial is required to be generated for each bending angle (instead of thousands of trials required by the conventional algorithm), this method can dramatically reduce the simulation time. The profiling results of our Monte Carlo simulation code show that trial generation, which used to be the most time consuming process, is no longer the time dominating component of the simulation.

  7. Structural elucidation and physicochemical properties of mononuclear Uranyl(VI) complexes incorporating dianionic units

    PubMed Central

    Azam, Mohammad; Velmurugan, Gunasekaran; Wabaidur, Saikh Mohammad; Trzesowska-Kruszynska, Agata; Kruszynski, Rafal; Al-Resayes, Saud I.; Al-Othman, Zeid A.; Venuvanalingam, Ponnambalam

    2016-01-01

    Two derivatives of organouranyl mononuclear complexes [UO2(L)THF] (1) and [UO2(L)Alc] (2), where L = (2,2′-(1E,1′E)-(2,2-dimethylpropane-1,3-dyl)bis(azanylylidene, THF = Tetrahydrofuran, Alc = Alcohol), have been prepared. These complexes have been determined by elemental analyses, single crystal X-ray crystallography and various spectroscopic studies. Moreover, the structure of these complexes have also been studied by DFT and time dependent DFT measurements showing that both the complexes have distorted pentagonal bipyramidal environment around uranyl ion. TD-DFT results indicate that the complex 1 displays an intense band at 458.7 nm which is mainly associated to the uranyl centered LMCT, where complex 2 shows a band at 461.8 nm that have significant LMCT character. The bonding has been further analyzed by EDA and NBO. The photocatalytic activity of complexes 1 and 2 for the degradation of rhodamine-B (RhB) and methylene blue (MB) under the irradiation of 500W Xe lamp has been explored, and found more efficient in presence of complex 1 than complex 2 for both dyes. In addition, dye adsorption and photoluminescence properties have also been discussed for both complexes. PMID:27595801

  8. Structural elucidation and physicochemical properties of mononuclear Uranyl(VI) complexes incorporating dianionic units.

    PubMed

    Azam, Mohammad; Velmurugan, Gunasekaran; Wabaidur, Saikh Mohammad; Trzesowska-Kruszynska, Agata; Kruszynski, Rafal; Al-Resayes, Saud I; Al-Othman, Zeid A; Venuvanalingam, Ponnambalam

    2016-01-01

    Two derivatives of organouranyl mononuclear complexes [UO2(L)THF] (1) and [UO2(L)Alc] (2), where L = (2,2'-(1E,1'E)-(2,2-dimethylpropane-1,3-dyl)bis(azanylylidene, THF = Tetrahydrofuran, Alc = Alcohol), have been prepared. These complexes have been determined by elemental analyses, single crystal X-ray crystallography and various spectroscopic studies. Moreover, the structure of these complexes have also been studied by DFT and time dependent DFT measurements showing that both the complexes have distorted pentagonal bipyramidal environment around uranyl ion. TD-DFT results indicate that the complex 1 displays an intense band at 458.7 nm which is mainly associated to the uranyl centered LMCT, where complex 2 shows a band at 461.8 nm that have significant LMCT character. The bonding has been further analyzed by EDA and NBO. The photocatalytic activity of complexes 1 and 2 for the degradation of rhodamine-B (RhB) and methylene blue (MB) under the irradiation of 500W Xe lamp has been explored, and found more efficient in presence of complex 1 than complex 2 for both dyes. In addition, dye adsorption and photoluminescence properties have also been discussed for both complexes. PMID:27595801

  9. Structural elucidation and physicochemical properties of mononuclear Uranyl(VI) complexes incorporating dianionic units.

    PubMed

    Azam, Mohammad; Velmurugan, Gunasekaran; Wabaidur, Saikh Mohammad; Trzesowska-Kruszynska, Agata; Kruszynski, Rafal; Al-Resayes, Saud I; Al-Othman, Zeid A; Venuvanalingam, Ponnambalam

    2016-09-06

    Two derivatives of organouranyl mononuclear complexes [UO2(L)THF] (1) and [UO2(L)Alc] (2), where L = (2,2'-(1E,1'E)-(2,2-dimethylpropane-1,3-dyl)bis(azanylylidene, THF = Tetrahydrofuran, Alc = Alcohol), have been prepared. These complexes have been determined by elemental analyses, single crystal X-ray crystallography and various spectroscopic studies. Moreover, the structure of these complexes have also been studied by DFT and time dependent DFT measurements showing that both the complexes have distorted pentagonal bipyramidal environment around uranyl ion. TD-DFT results indicate that the complex 1 displays an intense band at 458.7 nm which is mainly associated to the uranyl centered LMCT, where complex 2 shows a band at 461.8 nm that have significant LMCT character. The bonding has been further analyzed by EDA and NBO. The photocatalytic activity of complexes 1 and 2 for the degradation of rhodamine-B (RhB) and methylene blue (MB) under the irradiation of 500W Xe lamp has been explored, and found more efficient in presence of complex 1 than complex 2 for both dyes. In addition, dye adsorption and photoluminescence properties have also been discussed for both complexes.

  10. Metal to ligand charge-transfer photochemistry of metal-metal bonded complexes. 5. ESR spectra of stable rhenium-. cap alpha. -diimine and spin-trapped manganese-. cap alpha. -diimine radicals

    SciTech Connect

    Andrea, R.R.; de Lange, W.G.J.; van der Graaf, T.; Rijkhoff, M.; Stufkens, D.J.; Oskam, A.

    1988-05-01

    Irradiation (lambda greater than or equal to 320 nm) of (CO)/sub 5/MM'(CO)/sub 3/L and Ph/sub 3/SnM'(CO)/sub 3/L (M, M' = Mn, Re; L = ..cap alpha..-diimine = 2,2'-bipyridine, 1,10-phenanthroline, pyridine-2-carbaldehyde imine, and 1,4-diaza-1,3-butadiene) leads to homolysis of the metal-metal bond yielding fairly stable solvated radicals SM'(CO)/sub 3/L/sup ./. These paramagnetic species have been studied by ESR spectroscopy in solution directly or by using nitroso-2,2-dimethylpropane as a spin-trapping reagent. The ESR spectra show extensive hyperfine splittings of the unpaired electron with the nuclei /sup 14/N, /sup 1/H, and /sup 55/Mn or /sup 185,187/Re. From the observed and computer-simulated coupling constants important information could be derived about the electronic structure of the singly occupied molecular orbital (SOMO). After in situ addition of P(OPh)/sub 3/, P(OMe)/sub 3/, or pyridine (=L') to Re(CO)/sub 3/(t-Bu-DAB)/sup ./, the new paramagnetic adducts axial-(L')Re(CO)/sub 3/(t-Bu-DAB)/sup ./ could be identified.

  11. Structural elucidation and physicochemical properties of mononuclear Uranyl(VI) complexes incorporating dianionic units

    NASA Astrophysics Data System (ADS)

    Azam, Mohammad; Velmurugan, Gunasekaran; Wabaidur, Saikh Mohammad; Trzesowska-Kruszynska, Agata; Kruszynski, Rafal; Al-Resayes, Saud I.; Al-Othman, Zeid A.; Venuvanalingam, Ponnambalam

    2016-09-01

    Two derivatives of organouranyl mononuclear complexes [UO2(L)THF] (1) and [UO2(L)Alc] (2), where L = (2,2‧-(1E,1‧E)-(2,2-dimethylpropane-1,3-dyl)bis(azanylylidene, THF = Tetrahydrofuran, Alc = Alcohol), have been prepared. These complexes have been determined by elemental analyses, single crystal X-ray crystallography and various spectroscopic studies. Moreover, the structure of these complexes have also been studied by DFT and time dependent DFT measurements showing that both the complexes have distorted pentagonal bipyramidal environment around uranyl ion. TD-DFT results indicate that the complex 1 displays an intense band at 458.7 nm which is mainly associated to the uranyl centered LMCT, where complex 2 shows a band at 461.8 nm that have significant LMCT character. The bonding has been further analyzed by EDA and NBO. The photocatalytic activity of complexes 1 and 2 for the degradation of rhodamine-B (RhB) and methylene blue (MB) under the irradiation of 500W Xe lamp has been explored, and found more efficient in presence of complex 1 than complex 2 for both dyes. In addition, dye adsorption and photoluminescence properties have also been discussed for both complexes.

  12. Identification of in vitro and in vivo human metabolites of the new psychoactive substance nitracaine by liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.

    PubMed

    Negreira, Noelia; Kinyua, Juliet; De Brabanter, Nik; Maudens, Kristof; van Nuijs, Alexander L N

    2016-07-01

    The purpose of this work was to investigate the in vitro metabolism of nitracaine, a new psychoactive substance, using human liver microsome incubations, to evaluate the cytochrome P450 (CYP) enzyme isoforms responsible for the phase-I metabolism and to compare the information from the in vitro experiments with data resulting from an authentic user's urine sample. Accurate mass spectra of metabolites were obtained using liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) and were used in the structural identification of metabolites. Two major and three minor phase-I metabolites were identified from the in vitro experiments. The observed phase-I metabolites were formed through N-deethylation, N,N-deethylation, N-hydroxylation, and de-esterification, with CYP2B6 and CYP2C19 being the main enzymes catalyzing their formation. One glucuronidated product was identified in the phase-II metabolism experiments. All of these metabolites are reported for the first time in this study except the N-deethylation product. All the in vitro metabolites except the minor N,N-deethylation product were also present in the human urine sample, thus demonstrating the reliability of the in vitro experiments in the prediction of the in vivo metabolism of nitracaine. In addition to the metabolites, three transformation products (p-nitrobenzoic acid, p-aminobenzoic acid, and 3-(diethylamino)-2,2-dimethylpropan-1-ol) were identified, as well as several glucuronides and glutamine derived of them. PMID:27185541

  13. Neopentane and solid acids: direct hydron exchange before cracking.

    PubMed

    Walspurger, Stéphane; Sun, Yinyong; Souna Sido, Abdelkarim Sani; Sommer, Jean

    2006-09-21

    The hydrogen/deuterium exchange reaction of 2,2-dimethylpropane (neopentane) over D(2)O-exchanged zeolites (MOR, FAU, BEA, MFI) using a batch recirculation reactor was studied by means of gas chromatography coupled with mass spectrometer. In the temperature range 473-573 K, H/D exchange proceeds without side reaction such as cracking at short contact times. Indeed the C-H bond has appeared favorably involved in the activation of neopentane compared to the less accessible C-C bond. The transition state allowing hydron exchange is most likely a carbonium species (pentacoordinated carbon) as in the case of the H/D exchange between methane and solid acid. The activation energies of the H/D exchange between neopentane and zeolites are the same for all zeolites indicating a common carbonium ion type transition state. On the basis of previous results in the case of the exchange between methane and liquid superacids, the deuterium exchange rates in neopentane were tentatively related to the acidity of the solids. However the order of activity MOR > MFI > BEA > FAU seems to be related to the size of the pores, which may suggest the involvement of a confinement effect in the zeolites cavities. Moreover we found that H/D exchange takes also place between neopentane and deuterated sulfated zirconia (SZ) emphasizing its strong acidity.

  14. Crystal Structure of Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26 at 0.95 Å Resolution: Dynamics of Catalytic Residues

    SciTech Connect

    Oakley, Aaron J.; Klvana, Martin; Otyepka, Michal; Nagata, Yuji; Wilce, Matthew C.J.; Damborsky, Jiri

    2010-11-16

    We present the structure of LinB, a 33-kDa haloalkane dehalogenase from Sphingomonas paucimobilis UT26, at 0.95 {angstrom} resolution. The data have allowed us to directly observe the anisotropic motions of the catalytic residues. In particular, the side-chain of the catalytic nucleophile, Asp108, displays a high degree of disorder. It has been modeled in two conformations, one similar to that observed previously (conformation A) and one strained (conformation B) that approached the catalytic base (His272). The strain in conformation B was mainly in the C{sub {alpha}}-C{sub {beta}}-C{sub {gamma}} angle (126{sup o}) that deviated by 13.4{sup o} from the 'ideal' bond angle of 112.6{sup o}. On the basis of these observations, we propose a role for the charge state of the catalytic histidine in determining the geometry of the catalytic residues. We hypothesized that double-protonation of the catalytic base (His272) reduces the distance between the side-chain of this residue and that of the Asp108. The results of molecular dynamics simulations were consistent with the structural data showing that protonation of the His272 side-chain nitrogen atoms does indeed reduce the distance between the side-chains of the residues in question, although the simulations failed to demonstrate the same degree of strain in the Asp108 C{sub {alpha}}-C{sub {beta}}-C{sub {gamma}} angle. Instead, the changes in the molecular dynamics structures were distributed over several bond and dihedral angles. Quantum mechanics calculations on LinB with 1-chloro-2,2-dimethylpropane as a substrate were performed to determine which active site conformations and protonation states were most likely to result in catalysis. It was shown that His272 singly protonated at N{sub {delta}1} and Asp108 in conformation A gave the most exothermic reaction ({Delta}H = -22 kcal/mol). With His272 doubly protonated at N{sub {delta}1} and N{sub {epsilon}2}, the reactions were only slightly exothermic or were endothermic

  15. Strong ferromagnetic exchange interactions in hinge-like Dy(O2Cu)2 complexes involving double oxygen bridges.

    PubMed

    Ida, Yumi; Ghosh, Soumavo; Ghosh, Ashutosh; Nojiri, Hiroyuki; Ishida, Takayuki

    2015-10-01

    Two trinuclear isomeric compounds, [{(Cu(II)(salpn))(Me(CO)Me)}2Dy(III)(NO3)3] (1) and [{Cu(II)(salpn)}2Dy(III)(H2O)(NO3)3]·MeOH (2), along with one polymeric compound, {[{Cu(II)(salpn)}2Dy(III)(NO3)3bpy]·MeOH·H2O}n (3), were synthesized using a metalloligand, [Cu(II)(salpn)], where H2salpn and bpy stand for N,N'-bis(salicylidene)-1,3-propanediamine and 4,4'-bipyridine, respectively. Compounds 1 and 2 were selectively prepared with two solvents: the less polar acetone led to the exclusive crystallization of 1 with a transoid trinuclear architecture, while more polar solvent methanol provided sole construction of 2 with a cisoid trinuclear architecture. Compound 3 was prepared from 1 or 2 after bpy was introduced as a bridge. The Dy and Cu ions are doubly bridged with oxygen atoms, and the core DyO2Cu skeletons are characterized by different "butterfly angles" of 140.9(1)°, 147.1(19)°, and 142.4(2)° for 1, 2, and 3, respectively. We have examined the molecular structures and magnetic properties of 1-3 using high-frequency electron paramagnetic resonance (HF-EPR), magnetization, and magnetic susceptibility techniques. These compounds showed slow magnetization reversal in the measurements of alternating current magnetic susceptibility. We analyzed EPR frequency-field diagrams using an effective spin-Hamiltonian including only one doublet of Dy sublevels and found that the exchange couplings are ferromagnetic in all compounds. The exchange coupling parameters JDy-Cu of 1, 2, and 3 were determined as 2.25 ± 0.05, 1.82 ± 0.04, and 1.79 ± 0.04 K, respectively. These values are larger than those found in previous research using EPR analysis on [Cu(II)(L(A))(C3H6O)Dy(III)(NO3)3] (H2L(A) = N,N'-bis(3-methoxysalicylidene)-1,3-diamino-2,2-dimethylpropane) and [Dy(III)L(B)2(NO3)2{Cu(II)(CH3OH)}2](NO3)(CH3OH) (H2L(B) = 2,6-bis(acetylaceto)pyridine). The present result shows an advantage of doubly oxygen-bridged motifs to built strong ferromagnetic interactions between

  16. Strong ferromagnetic exchange interactions in hinge-like Dy(O2Cu)2 complexes involving double oxygen bridges.

    PubMed

    Ida, Yumi; Ghosh, Soumavo; Ghosh, Ashutosh; Nojiri, Hiroyuki; Ishida, Takayuki

    2015-10-01

    Two trinuclear isomeric compounds, [{(Cu(II)(salpn))(Me(CO)Me)}2Dy(III)(NO3)3] (1) and [{Cu(II)(salpn)}2Dy(III)(H2O)(NO3)3]·MeOH (2), along with one polymeric compound, {[{Cu(II)(salpn)}2Dy(III)(NO3)3bpy]·MeOH·H2O}n (3), were synthesized using a metalloligand, [Cu(II)(salpn)], where H2salpn and bpy stand for N,N'-bis(salicylidene)-1,3-propanediamine and 4,4'-bipyridine, respectively. Compounds 1 and 2 were selectively prepared with two solvents: the less polar acetone led to the exclusive crystallization of 1 with a transoid trinuclear architecture, while more polar solvent methanol provided sole construction of 2 with a cisoid trinuclear architecture. Compound 3 was prepared from 1 or 2 after bpy was introduced as a bridge. The Dy and Cu ions are doubly bridged with oxygen atoms, and the core DyO2Cu skeletons are characterized by different "butterfly angles" of 140.9(1)°, 147.1(19)°, and 142.4(2)° for 1, 2, and 3, respectively. We have examined the molecular structures and magnetic properties of 1-3 using high-frequency electron paramagnetic resonance (HF-EPR), magnetization, and magnetic susceptibility techniques. These compounds showed slow magnetization reversal in the measurements of alternating current magnetic susceptibility. We analyzed EPR frequency-field diagrams using an effective spin-Hamiltonian including only one doublet of Dy sublevels and found that the exchange couplings are ferromagnetic in all compounds. The exchange coupling parameters JDy-Cu of 1, 2, and 3 were determined as 2.25 ± 0.05, 1.82 ± 0.04, and 1.79 ± 0.04 K, respectively. These values are larger than those found in previous research using EPR analysis on [Cu(II)(L(A))(C3H6O)Dy(III)(NO3)3] (H2L(A) = N,N'-bis(3-methoxysalicylidene)-1,3-diamino-2,2-dimethylpropane) and [Dy(III)L(B)2(NO3)2{Cu(II)(CH3OH)}2](NO3)(CH3OH) (H2L(B) = 2,6-bis(acetylaceto)pyridine). The present result shows an advantage of doubly oxygen-bridged motifs to built strong ferromagnetic interactions between