Science.gov

Sample records for 2-year time period

  1. 41 CFR 302-2.10 - Does the 2-year time period in § 302-2.8 include time that I cannot travel and/or transport my...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false Does the 2-year time period in § 302-2.8 include time that I cannot travel and/or transport my household effects due to... time that I cannot travel and/or transport my household effects due to shipping restrictions to or...

  2. 41 CFR 302-2.10 - Does the 2-year time period in § 302-2.8 include time that I cannot travel and/or transport my...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false Does the 2-year time period in § 302-2.8 include time that I cannot travel and/or transport my household effects due to... time that I cannot travel and/or transport my household effects due to shipping restrictions to or...

  3. Comparison between visual clinical examination and the replica method for assessments of sealant retention over a 2-year period.

    PubMed

    Hu, Xuan; Chen, Xi; Ye, Lu; Fan, Ming-Wen; Huysmans, Marie-Charlotte; Frencken, Jo E

    2014-06-01

    To compare the levels of agreement and the survival rates of sealant retention for different sealing materials over a 2-year period assessed using the visual clinical examination and replica methods, sealant retention data were obtained by visual clinical examination and from replicas of the same sealed tooth at baseline and at 0.5-, 1- and 2-year evaluation points in 407 children and were compared for agreement using kappa coefficients. Survival curves of retained sealants on occlusal surfaces were created using modified categorisation (fully retained sealants and those having all pits and fissures partly covered with the sealant material versus completely lost sealants that included pit and fissure systems that had ≥1 pit re-exposed) according to the Kaplan-Meier method. The kappa coefficient for the agreement between both assessment methods over the three evaluation time points combined was 0.38 (95% confidence interval (CI): 0.35-0.41). More sealant retention was observed from replicas than through visual clinical examination. Cumulative survival curves at the three evaluation times were not statistically significantly higher when assessed from replicas (P=0.47). Using the replica method, more retained sealant material was observed than through visual clinical examination during the 2-year period. This finding did not result in a difference in the survival rates of sealants assessed by the two assessment methods. When replicas cast in die stone are used for assessing sealant retention, the level of reliability of the data is higher than that of data obtained through the commonly used visual clinical examination, particularly if such assessments are conducted over time.

  4. Sexual Identity, Attractions, and Behavior among Young Sexual-Minority Women over a 2-Year Period.

    ERIC Educational Resources Information Center

    Diamond, Lisa M.

    2000-01-01

    Examined sexual identities, attractions, and behaviors of sexual-minority women in 2-year follow-up of women first interviewed at 16-23 years. Found half the participants had changed sexual-minority orientations more than once; one- third changed identities since the first interview. Found changes in sexual attractions were larger among bisexuals…

  5. Clinical Effects and Radiological Results of Vertebroplasty: Over a 2-year Follow-Up Period

    PubMed Central

    Nam, Han Ga Wi; Shin, Il Young; Moon, Seung-Myung; Hwang, Hyung Sik

    2012-01-01

    Objective We investigated the association between clinical and radiological results and assessed the radiological changes according to the distribution pattern and amount of injected cement after vertebroplasty. Methods Two hundred and one patients underwent vertebroplasty; of these, 15 were follow up for more than 2 years. For radiological analysis, we grouped the patients according to cement distribution as follows: group 1, unilateral, unilateral distribution of cement; group 2, bilateral-uneven, bilateral distribution of cement but separated mass; and group 3, bilateral-even, bilateral single mass of cement. To compare radiologic with clinical results, we assessed the visual analogue scale (VAS) score, amount of injected cement, bone mineral density (BMD), postoperative and follow-up vertebral body compression ratios, and postoperative and follow-up kyphotic angles. Results There were 4 (26.7%) patients in group 1, 6 (40.0%) in group 2, and 5 (33.3%) in group 3. The mean VAS score was 5.2 preoperatively, 1.8 postoperatively, and 3.2 at 2-year follow-up. The 2-year follow-up compression ratio was better in patients with even distribution of injected cement (group 2 and 3) than group 1. However, it was not statistically insignificant (p>0.05). The follow-up kyphotic angle was more aggravated in the group 1 than in the other groups (p<0.05). Conclusion Our study showed that vertebroplasty had a beneficial effect on pain relief, particularly in the immediate postoperative stage. The augmented spine tended to be more stable in the cases with increased amount and more even distribution of injected cement. PMID:25983842

  6. THE FREQUENCY OF T(14;18) IN BLOOD LYMPHOCYTES IS STABLE OVER A 2 YEAR PERIOD IN ADULTS

    EPA Science Inventory

    The Frequency of t(14;18) in Blood Lymphocytes Is Stable over a 2 Year Period in Adults

    As part of a multi-endpoint molecular epidemiology study on in utero environmental exposures, umbilical cord and adult blood lymphocytes were examined for the frequency of t(14;18) by ...

  7. Changes in strength over a 2-year period in professional rugby union players.

    PubMed

    Appleby, Brendyn; Newton, Robert U; Cormie, Prue

    2012-09-01

    The purpose of this study was to assess the magnitude of upper and lower body strength changes in highly trained professional rugby union players after 2 years of training. An additional purpose was to examine if the changes in strength were influenced by the starting strength level, lean mass index (LMI), or chronological age. This longitudinal investigation tracked maximal strength and body composition over 3 consecutive years in 20 professional rugby union athletes. Maximal strength in the bench press and back squat and body composition was assessed during preseason resistance training sessions each year. The athletes completed a very rigorous training program throughout the duration of this study consisting of numerous resistance, conditioning and skills training sessions every week. The primary findings of this study were as follows: (a) Maximal upper and lower body strength was increased by 6.5-11.5% after 2 years of training (p = 0.000-0.002 for bench press; p = 0.277-0.165 for squat); (b) magnitude of the improvement was negatively associated with initial strength level (r = -0.569 to -0.712, p ≤ 0.05); (c) magnitude of improvement in lower body maximal strength was positively related to the change in LMI (an indicator of hypertrophy; r = 0.692-0.880, p ≤ 0.05); and (d) magnitude of improvement was not associated with the age of professional rugby union athletes (r = -0.068 to -0.345). It appears particularly important for training programs to be designed for continued muscle hypertrophy in highly trained athletes. Even in professional rugby union athletes, this must be achieved in the face of high volumes of aerobic and skills training if strength is to be increased.

  8. Improved prognosis in congenital diaphragmatic hernia: experience of 62 cases over 2-year period1

    PubMed Central

    Marshall, Alistair; Sumner, Edward

    1982-01-01

    During 1979 and 1980, 62 babies with congenital diaphragmatic hernia were admitted to the Hospitals for Sick Children. All 62 babies underwent surgical closure of the anatomical defect. There were 44 survivors and 18 deaths, a survival rate of 71%. Both the number treated and the overall survival rate were greater than any series reported for a similar period. The number of admissions may reflect earlier diagnosis and improved resuscitation, with safer and more rapid transfer to our units. The improved survival must be mainly attributed to our experience over the past few years which has consolidated understanding and methods of management and led to a close cooperation between surgeon and anaesthetist both in immediate management and in postoperative care. PMID:7108880

  9. Rehabilitation outcomes in children with cerebral palsy during a 2 year period

    PubMed Central

    İçağasıoğlu, Afitap; Mesci, Erkan; Yumusakhuylu, Yasemin; Turgut, Selin Turan; Murat, Sadiye

    2015-01-01

    [Purpose] To observe motor and functional progress of children with cerebral palsy during 2 years. [Subjects and Methods] Pediatric cerebral palsy patients aged 3–15 years (n = 35/69) with 24-month follow-up at our outpatient cerebral palsy clinic were evaluated retrospectively. The distribution of cerebral palsy types was as follows: diplegia (n = 19), hemiplegia (n = 4), and quadriplegia (n = 12). Participants were divided into 3 groups according to their Gross Motor Functional Classification System scores (i.e., mild, moderate, and severe). All participants were evaluated initially and at the final assessment 2 years later. During this time, patients were treated 3 times/week. Changes in motor and functional abilities were assessed based on Gross Motor Function Measure-88 and Wee Functional Independence Measure. [Results] Significant improvements were observed in Gross Motor Function Measure-88 and Wee Functional Independence Measure results in all 35 patients at the end of 2 years. The Gross Motor Function Measure-88 scores correlated with Wee Functional Independence Measure Scores. Marked increases in motor and functional capabilities in mild and moderate cerebral palsy patients were observed in the subgroup assessments, but not in those with severe cerebral palsy. [Conclusion] Rehabilitation may greatly help mild and moderate cerebral palsy patients achieve their full potential. PMID:26644677

  10. Rehabilitation outcomes in children with cerebral palsy during a 2 year period.

    PubMed

    İçağasıoğlu, Afitap; Mesci, Erkan; Yumusakhuylu, Yasemin; Turgut, Selin Turan; Murat, Sadiye

    2015-10-01

    [Purpose] To observe motor and functional progress of children with cerebral palsy during 2 years. [Subjects and Methods] Pediatric cerebral palsy patients aged 3-15 years (n = 35/69) with 24-month follow-up at our outpatient cerebral palsy clinic were evaluated retrospectively. The distribution of cerebral palsy types was as follows: diplegia (n = 19), hemiplegia (n = 4), and quadriplegia (n = 12). Participants were divided into 3 groups according to their Gross Motor Functional Classification System scores (i.e., mild, moderate, and severe). All participants were evaluated initially and at the final assessment 2 years later. During this time, patients were treated 3 times/week. Changes in motor and functional abilities were assessed based on Gross Motor Function Measure-88 and Wee Functional Independence Measure. [Results] Significant improvements were observed in Gross Motor Function Measure-88 and Wee Functional Independence Measure results in all 35 patients at the end of 2 years. The Gross Motor Function Measure-88 scores correlated with Wee Functional Independence Measure Scores. Marked increases in motor and functional capabilities in mild and moderate cerebral palsy patients were observed in the subgroup assessments, but not in those with severe cerebral palsy. [Conclusion] Rehabilitation may greatly help mild and moderate cerebral palsy patients achieve their full potential.

  11. Television and video viewing time among children aged 2 years - Oregon, 2006-2007.

    PubMed

    2010-07-16

    Excessive exposure of children to television and videos (viewing time) is associated with impaired childhood development and childhood obesity. In 2001, the American Academy of Pediatrics (AAP) recommended that children watch no more than 1 to 2 hours of "quality programming" per day, and that televisions be removed from children's bedrooms. To determine the risk for excessive viewing time among children aged 2 years, CDC and the Oregon Public Health Division analyzed 2006 and 2007 data from the Oregon Pregnancy Risk Assessment Monitoring Survey follow-back survey (Oregon PRAMS-2), which was used to re-interview mothers who had participated in PRAMS. This report summarizes the results of that analysis, which indicated that, on a typical day, 19.6% of children aged 2 years spent >or=2 hours watching television or videos. A total of 18.2% of children had a television in their bedroom; these children were more likely to have >or=2 hours viewing time compared with children without a television in the bedroom (34.1% versus 16.3%). In multivariable analysis, >or=2 hours of viewing time was positively associated with the presence of a television in the child's bedroom, non-Hispanic black maternal race/ethnicity, fewer than four outings with the child during the preceding week, and was negatively associated with obtaining child care in a child care center. In Oregon, these findings support the AAP recommendations that health professionals, parents, and caregivers recognize the extent of children's media consumption, and that televisions be removed from children's bedrooms. Other states should consider conducting similar surveys.

  12. Incorporating Spectra Into Periodic Timing

    NASA Astrophysics Data System (ADS)

    Connors, Alanna; Hong, J.; Protopapas, P.; Kashyap, V.

    2011-09-01

    The Chandra surveys have resulted in a wealth of data on low-luminosity X-ray sources (Lx 1030-34 erg/s) of Galactic scales beyond the local solar neighborhood. Many of these are compact binaries, in particular, cataclysmic variables, often identified by their periodic X-ray variability and spectra. Hong et al. (2009, 2011) have used energy quantiles (Hong, Schlegel & Grindlay, 2004) as a fast, robust indicator of spectral hardness and absorption of the X-ray sources. Energy quantiles also enable a simple but effective illustration of spectral changes with phase in these periodic systems: e.g. absorption by the accreting material is understood to drive the periodic light-curves. An interesting question is how to best make use of the information encapsulated in the periodic change in energy spectrum, along with the periodic change in intensity, especially for cases of ambiguous period determination? And, how to do it computationally efficiently? A first approach is to do the period search in intensity, as is standard; and then use a criterion of spectral variation to verify possible periods. Huijse, Zegers & Protopapas (2011) recently demonstrated a powerful period estimation technique using information potential and correntropy embedded in the light curve. Similar quantities based on energies (or energy quantiles) of X-ray photons can serve as criteria of spectral variation. A different approach treats the spectrum variations and intensity variations completely independently, searching through period-space in each, and then combining the results. A more general method would include both at the same time, looking for statistically significant variations above what is expected for a constant (in intensity and spectrum).

  13. Factors associated with seclusion in a statewide forensic psychiatric service in Australia over a 2-year period.

    PubMed

    Thomas, Stuart D M; Daffern, Michael; Martin, Trish; Ogloff, James R P; Thomson, Lindsay D G; Ferguson, Murray

    2009-02-01

    Despite seclusion being described as one of the most ethically- and legally-controversial management options available, it remains a widely-used clinical strategy for managing disruptive, aggressive, and violent behaviour. This study sought to determine how frequently seclusion was used, the common characteristics of those secluded and not secluded, and the degree to which the Level of Service Inventory - Revised: Screening Version (LSI-R: SV) could predict seclusion. The study was retrospective, covering the first 2 years of operation of a statewide forensic psychiatry hospital in Victoria, Australia. Data were collected from individual case files, electronic databases, and paper copies of records pertaining to violent incidents and episodes of seclusion. Eighty five (44%) of the 193 patients admitted during this period were secluded. Those secluded were significantly younger and had a more established psychiatric history. LSI-R: SV scores were significantly and positively associated with being secluded. A statistical model containing three LSI-R: SV items, along with age on admission and psychiatric history, achieved an area under the curve of 0.74. Seclusion is used on a regular basis in response to a range of different forms of aggressive behaviour of different severity. The LSI-R: SV demonstrated moderate-to-good accuracy in predicting seclusion and warrants further research using detailed prospective methodologies.

  14. 43 CFR 10010.45 - Time periods.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Time periods. 10010.45 Section 10010.45... Environmental Impact Statements § 10010.45 Time periods. (a) The minimum review period for a draft EIS will be... proposed reductions in time periods or any extensions of time periods proposed by those agencies....

  15. 43 CFR 10010.45 - Time periods.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Time periods. 10010.45 Section 10010.45... Environmental Impact Statements § 10010.45 Time periods. (a) The minimum review period for a draft EIS will be... proposed reductions in time periods or any extensions of time periods proposed by those agencies....

  16. 43 CFR 10010.45 - Time periods.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Time periods. 10010.45 Section 10010.45... Environmental Impact Statements § 10010.45 Time periods. (a) The minimum review period for a draft EIS will be... proposed reductions in time periods or any extensions of time periods proposed by those agencies....

  17. Time domain period determination techniques

    NASA Technical Reports Server (NTRS)

    Stellingwerf, R. F.

    1980-01-01

    Two simple period determination schemes are discussed. They are well suited to problems involving non-sinusoidal periodic phenomena sampled at a few irregularly spaced points. Statistical properties are discussed. The techniques are applied to the double mode Cepheids BK Cen and TU Cas as test cases.

  18. 41 CFR 302-11.22 - May the 2-year time limitation be extended by my agency?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false May the 2-year time... Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time Limitations § 302-11.22...

  19. 41 CFR 302-11.22 - May the 2-year time limitation be extended by my agency?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false May the 2-year time... Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time Limitations § 302-11.22...

  20. Association between maternal depressive symptoms in the early post-natal period and responsiveness in feeding at child age 2 years.

    PubMed

    Mallan, Kimberley M; Daniels, Lynne A; Wilson, Jacinda L; Jansen, Elena; Nicholson, Jan M

    2015-10-01

    Maternal depression is a known risk factor for poor outcomes for children. Pathways to these poor outcomes relate to reduced maternal responsiveness or sensitivity to the child. Impaired responsiveness potentially impacts the feeding relationship and thus may be a risk factor for inappropriate feeding practices. The aim of this study was to examine the longitudinal relationships between self-reported maternal post-natal depressive symptoms at child age 4 months and feeding practices at child age 2 years in a community sample. Participants were Australian first-time mothers allocated to the control group of the NOURISH randomized controlled trial when infants were 4 months old. Complete data from 211 mothers (of 346 allocated) followed up when their children were 2 years of age (51% girls) were available for analysis. The relationship between Edinburgh Postnatal Depression Scale (EPDS) score (child age 4 months) and child feeding practices (child age 2 years) was tested using hierarchical linear regression analysis adjusted for maternal and child characteristics. Higher EPDS score was associated with less responsive feeding practices at child age 2 years: greater pressure [β = 0.18, 95% confidence interval (CI): 0.04-0.32, P = 0.01], restriction (β = 0.14, 95% CI: 0.001-0.28, P = 0.05), instrumental (β = 0.14, 95% CI: 0.005-0.27, P = 0.04) and emotional (β = 0.15, 95% CI: 0.01-0.29, P = 0.03) feeding practices (ΔR(2) values: 0.02-0.03, P < 0.05). This study provides evidence for the proposed link between maternal post-natal depressive symptoms and lower responsiveness in child feeding. These findings suggest that the provision of support to mothers experiencing some levels of depressive symptomatology in the early post-natal period may improve responsiveness in the child feeding relationship.

  1. Association between maternal depressive symptoms in the early post-natal period and responsiveness in feeding at child age 2 years.

    PubMed

    Mallan, Kimberley M; Daniels, Lynne A; Wilson, Jacinda L; Jansen, Elena; Nicholson, Jan M

    2015-10-01

    Maternal depression is a known risk factor for poor outcomes for children. Pathways to these poor outcomes relate to reduced maternal responsiveness or sensitivity to the child. Impaired responsiveness potentially impacts the feeding relationship and thus may be a risk factor for inappropriate feeding practices. The aim of this study was to examine the longitudinal relationships between self-reported maternal post-natal depressive symptoms at child age 4 months and feeding practices at child age 2 years in a community sample. Participants were Australian first-time mothers allocated to the control group of the NOURISH randomized controlled trial when infants were 4 months old. Complete data from 211 mothers (of 346 allocated) followed up when their children were 2 years of age (51% girls) were available for analysis. The relationship between Edinburgh Postnatal Depression Scale (EPDS) score (child age 4 months) and child feeding practices (child age 2 years) was tested using hierarchical linear regression analysis adjusted for maternal and child characteristics. Higher EPDS score was associated with less responsive feeding practices at child age 2 years: greater pressure [β = 0.18, 95% confidence interval (CI): 0.04-0.32, P = 0.01], restriction (β = 0.14, 95% CI: 0.001-0.28, P = 0.05), instrumental (β = 0.14, 95% CI: 0.005-0.27, P = 0.04) and emotional (β = 0.15, 95% CI: 0.01-0.29, P = 0.03) feeding practices (ΔR(2) values: 0.02-0.03, P < 0.05). This study provides evidence for the proposed link between maternal post-natal depressive symptoms and lower responsiveness in child feeding. These findings suggest that the provision of support to mothers experiencing some levels of depressive symptomatology in the early post-natal period may improve responsiveness in the child feeding relationship. PMID:24784325

  2. Pubertal Timing and Substance Use in Middle Adolescence: A 2-Year Follow-Up Study

    ERIC Educational Resources Information Center

    Kaltiala-Heino, Riittakerttu; Koivisto, Anna-Maija; Marttunen, Mauri; Frojd, Sari

    2011-01-01

    Earlier research has associated early puberty with emotional and behavioral symptoms particularly among girls, while among boys, findings have been contradictory as to whether risks are associated with early or late pubertal timing. We studied the association between pubertal timing and substance use behaviors in middle adolescence in a 2-year…

  3. 24 CFR 58.21 - Time periods.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Time periods. 58.21 Section 58.21...: Environmental Review Procedures § 58.21 Time periods. All time periods in this part shall be counted in calendar days. The first day of a time period begins at 12:01 a.m. local time on the day following...

  4. 24 CFR 58.21 - Time periods.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Time periods. 58.21 Section 58.21...: Environmental Review Procedures § 58.21 Time periods. All time periods in this part shall be counted in calendar days. The first day of a time period begins at 12:01 a.m. local time on the day following...

  5. 24 CFR 58.21 - Time periods.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Time periods. 58.21 Section 58.21...: Environmental Review Procedures § 58.21 Time periods. All time periods in this part shall be counted in calendar days. The first day of a time period begins at 12:01 a.m. local time on the day following...

  6. 24 CFR 58.21 - Time periods.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Time periods. 58.21 Section 58.21...: Environmental Review Procedures § 58.21 Time periods. All time periods in this part shall be counted in calendar days. The first day of a time period begins at 12:01 a.m. local time on the day following...

  7. 24 CFR 58.21 - Time periods.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Time periods. 58.21 Section 58.21...: Environmental Review Procedures § 58.21 Time periods. All time periods in this part shall be counted in calendar days. The first day of a time period begins at 12:01 a.m. local time on the day following...

  8. Oxidative degradation in highly cross-linked and conventional polyethylene after 2 years of real-time shelf aging.

    PubMed

    Willie, Bettina M; Bloebaum, Roy D; Ashrafi, Shadi; Dearden, Colette; Steffensen, Trina; Hofmann, Aaron A

    2006-04-01

    Previous studies have reported oxidative degradation of conventional polyethylene (PE) components during shelf aging, following radiation. However, no studies have yet reported data concerning the effect of real-time shelf aging in the manufacturer's packaging on the oxidative degradation of commercially available highly cross-linking PE components. The null hypothesis tested was that in either highly cross-linked or conventional PE acetabular components there would be no significant difference in the amount of oxidative degradation between time zero PE liners and PE liners that had been real-time shelf aged for 2 years in their respective packaging. The results of the study indicated that after 2 years of real-time shelf aging, negligible oxidative degradation occurred with minimal changes in oxidation index, density, and percent crystallinity in commercially available highly cross-linked and conventional PE acetabular liners. These data suggested that oxidative degradation was not a clinical issue in the highly cross-linked and conventional PE components examined after 2 years of real-time shelf aging. It is likely that current manufacturing and packaging technologies have limited the previous clinical concerns related to oxidative degradation during shelf aging of highly cross-linked and conventional PE components.

  9. A 2-year-old Japanese girl with TNF receptor-associated periodic syndrome: A case report of the youngest diagnosed proband in Japan.

    PubMed

    Yasumura, Junko; Wago, Masakuni; Okada, Satoshi; Nishikomori, Ryuta; Takei, Syuji; Kobayashi, Masao

    2016-09-01

    We report a 2-year-old girl with tumor necrosis factor receptor-associated periodic syndrome (TRAPS) who is the youngest proband diagnosed in Japan. Recurrent fever had started at her 6 months of age, and she had the familial history of recurrent fever, suggesting underlying genetic disorder, in her father and grandfather. Careful clinical observation of characteristics of fever with disease course and the familial history of recurrent fever may lead to diagnosis of TRAPS in early infancy.

  10. Analysis of impulse oscillometric measures of lung function and respiratory system model parameters in small airway-impaired and healthy children over a 2-year period

    PubMed Central

    2011-01-01

    demonstrate that IOS parameters such as resistance at 5 Hz (R5), frequency-dependence of resistance (fdR: R5-R20), reactance area (AX), and parameter estimates of respiratory system such as Cp and Rp provide sensitive indicators of lung function and have the capacity to differentiate between obstructed and non-obstructed airway conditions. They are also capable of demonstrating airway growth-related changes over a two-year period. We conclude that the IOS parameters AX and the eRIC model derived parameter Cp are the most reliable parameters to track lung function in children before and after bronchodilator and over a time period (2 years). Which model is more suitable for interpreting IOS data? IOS data are equally well-modelled by eRIC and aRIC models, based on the close correlations of their corresponding parameters - excluding upper airway shunt compliance. The eRIC model is a more parsimonious and equally powerful model in capturing the differences in IOS indices between SAI and H children. Therefore, it may be considered a clinically-preferred model of lung function. PMID:21439045

  11. Incidence and Determinants of Endophthalmitis within 6 Months of Surgeries over a 2-Year Period at King Khaled Eye Specialist Hospital, Saudi Arabia: A Review

    PubMed Central

    Khandekar, Rajiv; Al-Motowa, Saeed; Alkatan, Hind M.; Karaoui, Mohammed; Ortiz, Anne

    2015-01-01

    Background: We present the incidence and determinants of endophthalmitis between July 2010 and June 2012 at King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. On its basis, we recommended recommendations to strengthen the infection prevention and control strategies. Methods: This is a retrospective review of health records type of study. The details of cases reported having endophthalmitis among those operated in 2 years of study period were studied. The incidence of endophthalmitis was calculated for different eye surgeries and epidemiological variables. The causative organisms in vitreous tap were reviewed. The visual outcomes 6 weeks following intervention/treatment of endophthalmmitis were also studied. Results: Of the 22,554 cases operated, 17 developed endophthalmitis. The incidence was 0.08% (95% confidence interval [CI] 0.04–0.11). The incidence of endophthlamitis among cataract surgeries was 0.12% (95% CI 0.04–0.21). Five specimens did not show any bacteria or fungus. Staphylococcus epidermis (3 cases) was the main pathogen identified. In 8 (47%) eyes, vision deteriorated in spite of treatment. In 5 (29%) eyes, it became stable and in 4 (23.5%) eyes, it improved following treatment. Signs of infection were noted in 1st week, 3 weeks and 12 weeks in 4, 6 and 5 eyes respectively. Late presentation of infection (6 months postoperatively) was reported in two eyes. Conclusions: A vigilant infection control unit in a large eye hospital helps in monitoring endophthalmitis related catastrophes and suggests timely preventive measures to reduce the occurrence and appropriate measures to limit visual disabilities following eye surgery related endophthalmitis. PMID:25949078

  12. Predominance and high antibiotic resistance of the emerging Clostridium difficile genotypes NAPCR1 and NAP9 in a Costa Rican hospital over a 2-year period without outbreaks.

    PubMed

    López-Ureña, Diana; Quesada-Gómez, Carlos; Montoya-Ramírez, Mónica; del Mar Gamboa-Coronado, María; Somogyi, Teresita; Rodríguez, César; Rodríguez-Cavallini, Evelyn

    2016-01-01

    Clostridium difficile is the major causative agent of nosocomial antibiotic-associated diarrhea. In a 2009 outbreak of C. difficile-associated diarrhea that was recorded in a major Costa Rican hospital, the hypervirulent NAP1 strain (45%) predominated together with a local genotype variant (NAPCR1, 31%). Both strains were fluoroquinolone-resistant and the NAPCR1 genotype, in addition, was resistant to clindamycin and rifampicin. We now report on the genotypes and antibiotic susceptibilities of 68 C. difficile isolates from a major Costa Rican hospital over a 2-year period without outbreaks. In contrast to our previous findings, no NAP1 strains were detected, and for the first time in a Costa Rican hospital, a significant fraction of the isolates were NAP9 strains (n=14, 21%). The local NAPCR1 genotype remained prevalent (n=18, 26%) and coexisted with 14 strains (21%) of classic hospital NAP types (NAP2, NAP4, and NAP6), eight new genotypes (12%), four environmental strains classified as NAP10 or NAP11 (6%), three strains without NAP designation (4%) and seven non-toxigenic strains (10%). All 68 strains were resistant to ciprofloxacin, 88% were resistant to clindamycin and 50% were resistant to moxifloxacin and rifampicin. Metronidazole and vancomycin susceptibilities were universal. The NAPCR1 and NAP9 strains, which have been associated with more severe clinical infections, were more resistant to antibiotics than the other strains. Altogether, our results confirm that the epidemiology of C. difficile infection is dynamic and that A(-)B(+) strains from the NAP9 type are on the rise not only in the developed world. Moreover, our results reveal that the local NAPCR1 strains still circulate in the country without causing outbreaks but with equally high antibiotic-resistance rates and levels. PMID:27165560

  13. 41 CFR 302-2.11 - May the 2-year time limitation for completing all aspects of a relocation be extended?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false May the 2-year time... and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 2-EMPLOYEES ELIGIBILITY REQUIREMENTS General Rules Time Limits § 302-2.11 May the 2-year time limitation...

  14. 41 CFR 302-2.11 - May the 2-year time limitation for completing all aspects of a relocation be extended?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false May the 2-year time... and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES INTRODUCTION 2-EMPLOYEES ELIGIBILITY REQUIREMENTS General Rules Time Limits § 302-2.11 May the 2-year time limitation...

  15. [Analysis of non-confraternity sports accidents in the surgical department of a former district hospital during the period of 2 years].

    PubMed

    Raschka, Ch; Raschka, S; Peikert, T

    2009-12-01

    This epidemiological study analyses all n = 1,659 outpatient and inpatient non-confraternity sports accidents treated during a 2-year period in a former district hospital. The largest share with 40.6% is soccer, followed by cycling (15%), general fitness sports (7.6%), outdoor sports (6.5%), winter sports (5.5%), and riding (5.2%). Soccer injuries rise steadily until the age of 30. Of 86 horse riding accidents a total of 68 involved women, but only 18 men (ratio 8 : 2). 53% of the horse riding accidents among women concern the age group between 10 and 20 years. 70.6% (79%) of the athletes under (over) 20 years were male, 29.4% (21%) female (p < 0.05). Topographically the lower extremities represent the most affected body region in all sports (runners 84.4%, soccer players 60.2%). Most accidents occur on a Sunday. The most common diagnosis is contusion, most commonly in martial arts (60.8%), followed by horse riding (51%). There is an astonishing dominance of soccer accidents given the fact that this study records all athletes, not just club athletes, unlike insurance studies. Important preventive measures would be a comprehensive biological training prophylaxis and the provision of communication of age-specific accident prevention proposals for the mainly affected sports. PMID:20052829

  16. Jovian electrons during solar quiet time periods

    NASA Astrophysics Data System (ADS)

    del Peral, L.; Gómez-Herrero, R.; Rodríguez-Frías, M. D.; Sequeiros, J.; Kunow, H.; Müller-Mellin, R.

    2002-03-01

    The electron spectrum in the energy range 150 keV to 10 MeV, measured by EPHIN sensor onboard SOHO observatory during 1996 quiet time periods, is presented. The results show that the dominant electron population is of jovian origin. The spectral indexes obtained range from 1.5 to 1.8. In this work an estimation of the emission intensity of electrons from the jovian magnetosphere is also obtained. Unexpected recurrence of jovian electrons at the middle of 1996 during poor Earth-Jupiter magnetic connection have been observed.

  17. 43 CFR 45.3 - How are time periods computed?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How are time periods computed? 45.3... IN FERC HYDROPOWER LICENSES General Provisions § 45.3 How are time periods computed? (a) General. Time periods are computed as follows: (1) The day of the act or event from which the period begins...

  18. 7 CFR 1.603 - How are time periods computed?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false How are time periods computed? 1.603 Section 1.603 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses General Provisions § 1.603 How are time periods computed? (a) General. Time periods are...

  19. 7 CFR 1.603 - How are time periods computed?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false How are time periods computed? 1.603 Section 1.603 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses General Provisions § 1.603 How are time periods computed? (a) General. Time periods are...

  20. 7 CFR 1.603 - How are time periods computed?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false How are time periods computed? 1.603 Section 1.603 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses General Provisions § 1.603 How are time periods computed? (a) General. Time periods are...

  1. 7 CFR 1.603 - How are time periods computed?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false How are time periods computed? 1.603 Section 1.603 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses General Provisions § 1.603 How are time periods computed? (a) General. Time periods are...

  2. 38 CFR 8.6 - Calculation of time period.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Calculation of time period. 8.6 Section 8.6 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS NATIONAL SERVICE LIFE INSURANCE Calculation of Time Period § 8.6 Calculation of time period. If the last day of...

  3. 38 CFR 8.6 - Calculation of time period.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Calculation of time period. 8.6 Section 8.6 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS NATIONAL SERVICE LIFE INSURANCE Calculation of Time Period § 8.6 Calculation of time period. If the last day of...

  4. 38 CFR 8.6 - Calculation of time period.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Calculation of time period. 8.6 Section 8.6 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS NATIONAL SERVICE LIFE INSURANCE Calculation of Time Period § 8.6 Calculation of time period. If the last day of...

  5. 38 CFR 8.6 - Calculation of time period.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Calculation of time period. 8.6 Section 8.6 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS NATIONAL SERVICE LIFE INSURANCE Calculation of Time Period § 8.6 Calculation of time period. If the last day of...

  6. 50 CFR 221.3 - How are time periods computed?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false How are time periods computed? 221.3 Section 221.3 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... Provisions § 221.3 How are time periods computed? (a) General. Time periods are computed as follows: (1)...

  7. 7 CFR 1.603 - How are time periods computed?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false How are time periods computed? 1.603 Section 1.603 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses General Provisions § 1.603 How are time periods computed? (a) General. Time periods are...

  8. Detecting unstable periodic orbits from transient chaotic time series

    PubMed

    Dhamala; Lai; Kostelich

    2000-06-01

    We address the detection of unstable periodic orbits from experimentally measured transient chaotic time series. In particular, we examine recurrence times of trajectories in the vector space reconstructed from an ensemble of such time series. Numerical experiments demonstrate that this strategy can yield periodic orbits of low periods even when noise is present. We analyze the probability of finding periodic orbits from transient chaotic time series and derive a scaling law for this probability. The scaling law implies that unstable periodic orbits of high periods are practically undetectable from transient chaos.

  9. Contact time periods in immunological synapse

    NASA Astrophysics Data System (ADS)

    Bush, Daniel R.; Chattopadhyay, Amit K.

    2014-10-01

    This paper resolves the long standing debate as to the proper time scale <τ> of the onset of the immunological synapse bond, the noncovalent chemical bond defining the immune pathways involving T cells and antigen presenting cells. Results from our model calculations show <τ> to be of the order of seconds instead of minutes. Close to the linearly stable regime, we show that in between the two critical spatial thresholds defined by the integrin:ligand pair (Δ2˜ 40-45 nm) and the T-cell receptor TCR:peptide-major-histocompatibility-complex pMHC bond (Δ1˜ 14-15 nm), <τ> grows monotonically with increasing coreceptor bond length separation δ (= Δ2-Δ1˜ 26-30 nm) while <τ> decays with Δ1 for fixed Δ2. The nonuniversal δ-dependent power-law structure of the probability density function further explains why only the TCR:pMHC bond is a likely candidate to form a stable synapse.

  10. Student Instruction Should Be Distributed over Long Time Periods

    ERIC Educational Resources Information Center

    Rohrer, Doug

    2015-01-01

    In many academic courses, students encounter a particular fact or concept many times over a period of a few weeks and then do not see it again during the remainder of the course. Are these brief instructional periods sufficient, or should the same amount of instruction be distributed over longer periods of time? This question was the focus of…

  11. 36 CFR 218.10 - Objection time periods and process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... holidays. However, when the time period expires on a Saturday, Sunday, or Federal holiday, the time is extended to the end of the next Federal working day as stated in the legal notice or to the end of...

  12. 36 CFR 218.26 - Objection time periods.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROJECT-LEVEL PREDECISIONAL ADMINISTRATIVE REVIEW PROCESS Provisions Specific to Project-Level Proposals Not Authorized Under Healthy Forests Restoration Act § 218.26 Objection time periods. (a) Time to...

  13. 36 CFR 218.32 - Objection time periods.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROJECT-LEVEL PREDECISIONAL ADMINISTRATIVE REVIEW PROCESS Provisions Specific to Proposed Projects Authorized Under the Healthy Forests Restoration Act § 218.32 Objection time periods. (a) Time to file...

  14. 36 CFR 218.32 - Objection time periods.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROJECT-LEVEL PREDECISIONAL ADMINISTRATIVE REVIEW PROCESS Provisions Specific to Proposed Projects Authorized Under the Healthy Forests Restoration Act § 218.32 Objection time periods. (a) Time to file...

  15. 36 CFR 218.26 - Objection time periods.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROJECT-LEVEL PREDECISIONAL ADMINISTRATIVE REVIEW PROCESS Provisions Specific to Project-Level Proposals Not Authorized Under Healthy Forests Restoration Act § 218.26 Objection time periods. (a) Time to...

  16. 19 CFR 158.21a - Time period.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 2 2011-04-01 2011-04-01 false Time period. 158.21a Section 158.21a Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... While in Customs Custody § 158.21a Time period. An abatement or refund of duties shall be made in...

  17. 19 CFR 158.21a - Time period.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 2 2012-04-01 2012-04-01 false Time period. 158.21a Section 158.21a Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... While in Customs Custody § 158.21a Time period. An abatement or refund of duties shall be made in...

  18. 43 CFR 45.3 - How are time periods computed?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false How are time periods computed? 45.3 Section 45.3 Public Lands: Interior Office of the Secretary of the Interior CONDITIONS AND PRESCRIPTIONS IN FERC HYDROPOWER LICENSES General Provisions § 45.3 How are time periods computed? (a)...

  19. 43 CFR 45.3 - How are time periods computed?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true How are time periods computed? 45.3 Section 45.3 Public Lands: Interior Office of the Secretary of the Interior CONDITIONS AND PRESCRIPTIONS IN FERC HYDROPOWER LICENSES General Provisions § 45.3 How are time periods computed? (a) General....

  20. 43 CFR 45.3 - How are time periods computed?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false How are time periods computed? 45.3 Section 45.3 Public Lands: Interior Office of the Secretary of the Interior CONDITIONS AND PRESCRIPTIONS IN FERC HYDROPOWER LICENSES General Provisions § 45.3 How are time periods computed? (a)...

  1. 43 CFR 45.3 - How are time periods computed?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false How are time periods computed? 45.3 Section 45.3 Public Lands: Interior Office of the Secretary of the Interior CONDITIONS AND PRESCRIPTIONS IN FERC HYDROPOWER LICENSES General Provisions § 45.3 How are time periods computed? (a)...

  2. 19 CFR 158.21a - Time period.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Time period. 158.21a Section 158.21a Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... While in Customs Custody § 158.21a Time period. An abatement or refund of duties shall be made in...

  3. Threshold dynamics of a time periodic reaction-diffusion epidemic model with latent period

    NASA Astrophysics Data System (ADS)

    Zhang, Liang; Wang, Zhi-Cheng; Zhao, Xiao-Qiang

    2015-05-01

    In this paper, we first propose a time-periodic reaction-diffusion epidemic model which incorporates simple demographic structure and the latent period of infectious disease. Then we introduce the basic reproduction number R0 for this model and prove that the sign of R0 - 1 determines the local stability of the disease-free periodic solution. By using the comparison arguments and persistence theory, we further show that the disease-free periodic solution is globally attractive if R0 < 1, while there is an endemic periodic solution and the disease is uniformly persistent if R0 > 1.

  4. Period04: Statistical analysis of large astronomical time series

    NASA Astrophysics Data System (ADS)

    Lenz, Patrick; Breger, Michel

    2014-07-01

    Period04 statistically analyzes large astronomical time series containing gaps. It calculates formal uncertainties, can extract the individual frequencies from the multiperiodic content of time series, and provides a flexible interface to perform multiple-frequency fits with a combination of least-squares fitting and the discrete Fourier transform algorithm. Period04, written in Java/C++, supports the SAMP communication protocol to provide interoperability with other applications of the Virtual Observatory. It is a reworked and extended version of Period98 (Sperl 1998) and PERIOD/PERDET (Breger 1990).

  5. A time-periodic reaction-diffusion epidemic model with infection period

    NASA Astrophysics Data System (ADS)

    Zhang, Liang; Wang, Zhi-Cheng

    2016-10-01

    In this paper, we propose a time-periodic and diffusive SIR epidemic model with constant infection period. By introducing the basic reproduction number R_0 via a next generation operator for this model, we show that the disease goes extinction if R_0 < 1; while the disease is uniformly persistent if R_0 > 1.

  6. Developmental milestones record - 2 years

    MedlinePlus

    Growth milestones for children - 2 years; Normal childhood growth milestones - 2 years; Childhood growth milestones - 2 years ... cause for concern if not seen by 2 years.) Can run with better coordination . (May still have ...

  7. Bacterial community shift is induced by dynamic environmental parameters in a changing coastal ecosystem (northern Adriatic, northeastern Mediterranean Sea)--a 2-year time-series study.

    PubMed

    Tinta, T; Vojvoda, J; Mozetič, P; Talaber, I; Vodopivec, M; Malfatti, F; Turk, V

    2015-10-01

    The potential link between the microbial dynamics and the environmental parameters was investigated in a semi-enclosed and highly dynamic coastal system (Gulf of Trieste, northern Adriatic Sea, NE Mediterranean Sea). Our comprehensive 2-year time-series study showed that despite the shallowness of this area, there was a significant difference between the surface and the bottom bacterial community structure. The bottom bacterial community was more diverse than the surface one and influenced by sediment re-suspension. The surface seawater temperature had a profound effect on bacterial productivity, while the bacterial community structure was more affected by freshwater-borne nutrients and phytoplankton blooms. Phytoplankton blooms caused an increase of Gammaproteobacteria (Alteromonadaceae, SAR86 and Vibrionaceae) and shift in dominance from SAR11 to Rhodobacteraceae taxon at the surface. Our results propose the importance of the water mass movements as drivers of freshwater-borne nutrients and of allochthonous microbial taxa. This study emphasizes the prediction power based on association networks analyses that are fed with long-term measurements of microbial and environmental parameters. These interaction maps offer valuable insights into the response of marine ecosystem to climate- and anthropogenic-driven stressors.

  8. Particle energization through time-periodic helical magnetic fields.

    PubMed

    Mitra, Dhrubaditya; Brandenburg, Axel; Dasgupta, Brahmananda; Niklasson, Eyvind; Ram, Abhay

    2014-04-01

    We solve for the motion of charged particles in a helical time-periodic ABC (Arnold-Beltrami-Childress) magnetic field. The magnetic field lines of a stationary ABC field with coefficients A=B=C=1 are chaotic, and we show that the motion of a charged particle in such a field is also chaotic at late times with positive Lyapunov exponent. We further show that in time-periodic ABC fields, the kinetic energy of a charged particle can increase indefinitely with time. At late times the mean kinetic energy grows as a power law in time with an exponent that approaches unity. For an initial distribution of particles, whose kinetic energy is uniformly distributed within some interval, the probability density function of kinetic energy is, at late times, close to a Gaussian but with steeper tails.

  9. Identifying multiple periodicities in sparse photon event time series

    NASA Astrophysics Data System (ADS)

    Koen, Chris

    2016-07-01

    The data considered are event times (e.g. photon arrival times, or the occurrence of sharp pulses). The source is multiperiodic, or the data could be multiperiodic because several unresolved sources contribute to the time series. Most events may be unobserved, either because the source is intermittent, or because some events are below the detection limit. The data may also be contaminated by spurious pulses. The problem considered is the determination of the periods in the data. A two-step procedure is proposed: in the first, a likely period is identified; in the second, events associated with this periodicity are removed from the time series. The steps are repeated until the remaining events do not exhibit any periodicity. A number of period-finding methods from the literature are reviewed, and a new maximum likelihood statistic is also introduced. It is shown that the latter is competitive compared to other techniques. The proposed methodology is tested on simulated data. Observations of two rotating radio transients are discussed, but contrary to claims in the literature, no evidence for multiperiodicity could be found.

  10. Optimal health insurance for multiple goods and time periods.

    PubMed

    Ellis, Randall P; Jiang, Shenyi; Manning, Willard G

    2015-05-01

    We examine the efficiency-based arguments for second-best optimal health insurance with multiple treatment goods and multiple time periods. Correlated shocks across health care goods and over time interact with complementarity and substitutability to affect optimal cost sharing. Health care goods that are substitutes or have positively correlated demand shocks should have lower optimal patient cost sharing. Positive serial correlations of demand shocks and uncompensated losses that are positively correlated with covered health services also reduce optimal cost sharing. Our results rationalize covering pharmaceuticals and outpatient spending more fully than is implied by static, one good, or one period models.

  11. Pseudo analytical solution to time periodic stiffness systems

    NASA Astrophysics Data System (ADS)

    Wang, Yan-Zhong; Zhou, Yuan-Zi

    2011-04-01

    An analytical form of state transition matrix for a system of equations with time periodic stiffness is derived in order to solve the free response and also allow for the determination of system stability and bifurcation. A pseudo-closed form complete solution for parametrically excited systems subjected to inhomogeneous generalized forcing is developed, based on the Fourier expansion of periodic matrices and the substitution of matrix exponential terms via Lagrange—Sylvester theorem. A Mathieu type of equation with large amplitude is presented to demonstrate the method of formulating state transition matrix and Floquet multipliers. A two-degree-of-freedom system with irregular time periodic stiffness characterized by spiral bevel gear mesh vibration is presented to find forced response in stability and instability. The obtained results are presented and discussed.

  12. Analysis of time-domain scattering by periodic structures

    NASA Astrophysics Data System (ADS)

    Gao, Yixian; Li, Peijun

    2016-11-01

    This paper is devoted to the mathematical analysis of a time-domain electromagnetic scattering by periodic structures which are known as diffraction gratings. The scattering problem is reduced equivalently into an initial-boundary value problem in a bounded domain by using an exact transparent boundary condition. The well-posedness and stability of the solution are established for the reduced problem. Moreover, a priori energy estimates are obtained with minimum regularity requirement for the data and explicit dependence on the time.

  13. 36 CFR 215.15 - Appeal time periods and process.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Appeal time periods and process. 215.15 Section 215.15 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NOTICE, COMMENT, AND APPEAL PROCEDURES FOR NATIONAL FOREST SYSTEM PROJECTS AND ACTIVITIES §...

  14. 36 CFR 215.15 - Appeal time periods and process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Appeal time periods and process. 215.15 Section 215.15 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NOTICE, COMMENT, AND APPEAL PROCEDURES FOR NATIONAL FOREST SYSTEM PROJECTS AND ACTIVITIES §...

  15. 36 CFR 215.15 - Appeal time periods and process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Appeal time periods and process. 215.15 Section 215.15 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NOTICE, COMMENT, AND APPEAL PROCEDURES FOR NATIONAL FOREST SYSTEM PROJECTS AND ACTIVITIES §...

  16. 36 CFR 215.15 - Appeal time periods and process.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Appeal time periods and process. 215.15 Section 215.15 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NOTICE, COMMENT, AND APPEAL PROCEDURES FOR NATIONAL FOREST SYSTEM PROJECTS AND ACTIVITIES §...

  17. 36 CFR 215.15 - Appeal time periods and process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Appeal time periods and process. 215.15 Section 215.15 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NOTICE, COMMENT, AND APPEAL PROCEDURES FOR NATIONAL FOREST SYSTEM PROJECTS AND ACTIVITIES §...

  18. 50 CFR 221.3 - How are time periods computed?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false How are time periods computed? 221.3 Section 221.3 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS PRESCRIPTIONS IN FERC HYDROPOWER LICENSES...

  19. 50 CFR 221.3 - How are time periods computed?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false How are time periods computed? 221.3 Section 221.3 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS PRESCRIPTIONS IN FERC HYDROPOWER LICENSES...

  20. 50 CFR 221.3 - How are time periods computed?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false How are time periods computed? 221.3 Section 221.3 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS PRESCRIPTIONS IN FERC HYDROPOWER LICENSES...

  1. 50 CFR 221.3 - How are time periods computed?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false How are time periods computed? 221.3 Section 221.3 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS PRESCRIPTIONS IN FERC HYDROPOWER LICENSES...

  2. Physical Activity in High School during "Free-Time" Periods

    ERIC Educational Resources Information Center

    Silva, Pedro; Sousa, Michael; Sá, Carla; Ribeiro, José; Mota, Jorge

    2015-01-01

    The purpose of this study was to examine youth physical activity (PA) in free-time periods during high school days and their contribution to total PA. Differences in terms of sex, age, body mass index and school level were assessed in a sample of Portuguese adolescents. Participants totalled 213 (135 girls), aged 14.6 ± 1.7, from two different…

  3. Time-periodic solutions of the Benjamin-Ono equation

    SciTech Connect

    Ambrose , D.M.; Wilkening, Jon

    2008-04-01

    We present a spectrally accurate numerical method for finding non-trivial time-periodic solutions of non-linear partial differential equations. The method is based on minimizing a functional (of the initial condition and the period) that is positive unless the solution is periodic, in which case it is zero. We solve an adjoint PDE to compute the gradient of this functional with respect to the initial condition. We include additional terms in the functional to specify the free parameters, which, in the case of the Benjamin-Ono equation, are the mean, a spatial phase, a temporal phase and the real part of one of the Fourier modes at t = 0. We use our method to study global paths of non-trivial time-periodic solutions connecting stationary and traveling waves of the Benjamin-Ono equation. As a starting guess for each path, we compute periodic solutions of the linearized problem by solving an infinite dimensional eigenvalue problem in closed form. We then use our numerical method to continue these solutions beyond the realm of linear theory until another traveling wave is reached (or until the solution blows up). By experimentation with data fitting, we identify the analytical form of the solutions on the path connecting the one-hump stationary solution to the two-hump traveling wave. We then derive exact formulas for these solutions by explicitly solving the system of ODE's governing the evolution of solitons using the ansatz suggested by the numerical simulations.

  4. False periodicities in quasar time-domain surveys

    NASA Astrophysics Data System (ADS)

    Vaughan, S.; Uttley, P.; Markowitz, A. G.; Huppenkothen, D.; Middleton, M. J.; Alston, W. N.; Scargle, J. D.; Farr, W. M.

    2016-09-01

    There have recently been several reports of apparently periodic variations in the light curves of quasars, e.g. PG 1302-102 by Graham et al. Any quasar showing periodic oscillations in brightness would be a strong candidate to be a close binary supermassive black hole and, in turn, a candidate for gravitational wave studies. However, normal quasars - powered by accretion on to a single, supermassive black hole - usually show stochastic variability over a wide range of time-scales. It is therefore important to carefully assess the methods for identifying periodic candidates from among a population dominated by stochastic variability. Using a Bayesian analysis of the light curve of PG 1302-102, we find that a simple stochastic process is preferred over a sinusoidal variation. We then discuss some of the problems one encounters when searching for rare, strictly periodic signals among a large number of irregularly sampled, stochastic time series, and use simulations of quasar light curves to illustrate these points. From a few thousand simulations of steep spectrum (`red noise') stochastic processes, we find many simulations that display few-cycle periodicity like that seen in PG 1302-102. We emphasize the importance of calibrating the false positive rate when the number of targets in a search is very large.

  5. Periodicity detection method for small-sample time series datasets.

    PubMed

    Tominaga, Daisuke

    2010-01-01

    Time series of gene expression often exhibit periodic behavior under the influence of multiple signal pathways, and are represented by a model that incorporates multiple harmonics and noise. Most of these data, which are observed using DNA microarrays, consist of few sampling points in time, but most periodicity detection methods require a relatively large number of sampling points. We have previously developed a detection algorithm based on the discrete Fourier transform and Akaike's information criterion. Here we demonstrate the performance of the algorithm for small-sample time series data through a comparison with conventional and newly proposed periodicity detection methods based on a statistical analysis of the power of harmonics.We show that this method has higher sensitivity for data consisting of multiple harmonics, and is more robust against noise than other methods. Although "combinatorial explosion" occurs for large datasets, the computational time is not a problem for small-sample datasets. The MATLAB/GNU Octave script of the algorithm is available on the author's web site: http://www.cbrc.jp/%7Etominaga/piccolo/. PMID:21151841

  6. The time-transgressive termination of the African Humid Period

    NASA Astrophysics Data System (ADS)

    Shanahan, Timothy M.; McKay, Nicholas P.; Hughen, Konrad A.; Overpeck, Jonathan T.; Otto-Bliesner, Bette; Heil, Clifford W.; King, John; Scholz, Christopher A.; Peck, John

    2015-02-01

    During the African Humid Period about 14,800 to 5,500 years ago, changes in incoming solar radiation during Northern Hemisphere summers led to the large-scale expansion and subsequent collapse of the African monsoon. Hydrologic reconstructions from arid North Africa show an abrupt onset and termination of the African Humid Period. These abrupt transitions have been invoked in arguments that the African monsoon responds rapidly to gradual forcing as a result of nonlinear land surface feedbacks. Here we present a reconstruction of precipitation in humid tropical West Africa for the past 20,000 years using the hydrogen isotope composition of leaf waxes preserved in sediments from Lake Bosumtwi, Ghana. We show that over much of tropical and subtropical Africa the monsoon responded synchronously and predictably to glacial reorganizations of overturning circulation in the Atlantic Ocean, but the response to the relatively weaker radiative forcing during the African Humid Period was more spatially and temporally complex. A synthesis of hydrologic reconstructions from across Africa shows that the termination of the African Humid Period was locally abrupt, but occurred progressively later at lower latitudes. We propose that this time-transgressive termination of the African Humid Period reflects declining rainfall intensity induced directly by decreasing summer insolation as well as the gradual southward migration of the tropical rainbelt that occurred during this interval.

  7. Periodic, Quasi-periodic and Chaotic Dynamics in Simple Gene Elements with Time Delays

    NASA Astrophysics Data System (ADS)

    Suzuki, Yoko; Lu, Mingyang; Ben-Jacob, Eshel; Onuchic, José N.

    2016-02-01

    Regulatory gene circuit motifs play crucial roles in performing and maintaining vital cellular functions. Frequently, theoretical studies of gene circuits focus on steady-state behaviors and do not include time delays. In this study, the inclusion of time delays is shown to entirely change the time-dependent dynamics for even the simplest possible circuits with one and two gene elements with self and cross regulations. These elements can give rise to rich behaviors including periodic, quasi-periodic, weak chaotic, strong chaotic and intermittent dynamics. We introduce a special power-spectrum-based method to characterize and discriminate these dynamical modes quantitatively. Our simulation results suggest that, while a single negative feedback loop of either one- or two-gene element can only have periodic dynamics, the elements with two positive/negative feedback loops are the minimalist elements to have chaotic dynamics. These elements typically have one negative feedback loop that generates oscillations, and another unit that allows frequent switches among multiple steady states or between oscillatory and non-oscillatory dynamics. Possible dynamical features of several simple one- and two-gene elements are presented in details. Discussion is presented for possible roles of the chaotic behavior in the robustness of cellular functions and diseases, for example, in the context of cancer.

  8. Periodic, Quasi-periodic and Chaotic Dynamics in Simple Gene Elements with Time Delays

    PubMed Central

    Suzuki, Yoko; Lu, Mingyang; Ben-Jacob, Eshel; Onuchic, José N.

    2016-01-01

    Regulatory gene circuit motifs play crucial roles in performing and maintaining vital cellular functions. Frequently, theoretical studies of gene circuits focus on steady-state behaviors and do not include time delays. In this study, the inclusion of time delays is shown to entirely change the time-dependent dynamics for even the simplest possible circuits with one and two gene elements with self and cross regulations. These elements can give rise to rich behaviors including periodic, quasi-periodic, weak chaotic, strong chaotic and intermittent dynamics. We introduce a special power-spectrum-based method to characterize and discriminate these dynamical modes quantitatively. Our simulation results suggest that, while a single negative feedback loop of either one- or two-gene element can only have periodic dynamics, the elements with two positive/negative feedback loops are the minimalist elements to have chaotic dynamics. These elements typically have one negative feedback loop that generates oscillations, and another unit that allows frequent switches among multiple steady states or between oscillatory and non-oscillatory dynamics. Possible dynamical features of several simple one- and two-gene elements are presented in details. Discussion is presented for possible roles of the chaotic behavior in the robustness of cellular functions and diseases, for example, in the context of cancer. PMID:26876008

  9. Periodic, Quasi-periodic and Chaotic Dynamics in Simple Gene Elements with Time Delays.

    PubMed

    Suzuki, Yoko; Lu, Mingyang; Ben-Jacob, Eshel; Onuchic, José N

    2016-02-15

    Regulatory gene circuit motifs play crucial roles in performing and maintaining vital cellular functions. Frequently, theoretical studies of gene circuits focus on steady-state behaviors and do not include time delays. In this study, the inclusion of time delays is shown to entirely change the time-dependent dynamics for even the simplest possible circuits with one and two gene elements with self and cross regulations. These elements can give rise to rich behaviors including periodic, quasi-periodic, weak chaotic, strong chaotic and intermittent dynamics. We introduce a special power-spectrum-based method to characterize and discriminate these dynamical modes quantitatively. Our simulation results suggest that, while a single negative feedback loop of either one- or two-gene element can only have periodic dynamics, the elements with two positive/negative feedback loops are the minimalist elements to have chaotic dynamics. These elements typically have one negative feedback loop that generates oscillations, and another unit that allows frequent switches among multiple steady states or between oscillatory and non-oscillatory dynamics. Possible dynamical features of several simple one- and two-gene elements are presented in details. Discussion is presented for possible roles of the chaotic behavior in the robustness of cellular functions and diseases, for example, in the context of cancer.

  10. Krylov-subspace acceleration of time periodic waveform relaxation

    SciTech Connect

    Lumsdaine, A.

    1994-12-31

    In this paper the author uses Krylov-subspace techniques to accelerate the convergence of waveform relaxation applied to solving systems of first order time periodic ordinary differential equations. He considers the problem in the frequency domain and presents frequency dependent waveform GMRES (FDWGMRES), a member of a new class of frequency dependent Krylov-subspace techniques. FDWGMRES exhibits many desirable properties, including finite termination independent of the number of timesteps and, for certain problems, a convergence rate which is bounded from above by the convergence rate of GMRES applied to the static matrix problem corresponding to the linear time-invariant ODE.

  11. Scheduling real-time, periodic jobs using imprecise results

    NASA Technical Reports Server (NTRS)

    Liu, Jane W. S.; Lin, Kwei-Jay; Natarajan, Swaminathan

    1987-01-01

    A process is called a monotone process if the accuracy of its intermediate results is non-decreasing as more time is spent to obtain the result. The result produced by a monotone process upon its normal termination is the desired result; the error in this result is zero. External events such as timeouts or crashes may cause the process to terminate prematurely. If the intermediate result produced by the process upon its premature termination is saved and made available, the application may still find the result unusable and, hence, acceptable; such a result is said to be an imprecise one. The error in an imprecise result is nonzero. The problem of scheduling periodic jobs to meet deadlines on a system that provides the necessary programming language primitives and run-time support for processes to return imprecise results is discussed. This problem differs from the traditional scheduling problems since the scheduler may choose to terminate a task before it is completed, causing it to produce an acceptable but imprecise result. Consequently, the amounts of processor time assigned to tasks in a valid schedule can be less than the amounts of time required to complete the tasks. A meaningful formulation of this problem taking into account the quality of the overall result is discussed. Three algorithms for scheduling jobs for which the effects of errors in results produced in different periods are not cumulative are described, and their relative merits are evaluated.

  12. Mimicking Nonequilibrium Steady States with Time-Periodic Driving

    NASA Astrophysics Data System (ADS)

    Raz, O.; Subaşı, Y.; Jarzynski, C.

    2016-04-01

    Under static conditions, a system satisfying detailed balance generically relaxes to an equilibrium state in which there are no currents. To generate persistent currents, either detailed balance must be broken or the system must be driven in a time-dependent manner. A stationary system that violates detailed balance evolves to a nonequilibrium steady state (NESS) characterized by fixed currents. Conversely, a system that satisfies instantaneous detailed balance but is driven by the time-periodic variation of external parameters—also known as a stochastic pump (SP)—reaches a periodic state with nonvanishing currents. In both cases, these currents are maintained at the cost of entropy production. Are these two paradigmatic scenarios effectively equivalent? For discrete-state systems, we establish a mapping between nonequilibrium stationary states and stochastic pumps. Given a NESS characterized by a particular set of stationary probabilities, currents, and entropy production rates, we show how to construct a SP with exactly the same (time-averaged) values. The mapping works in the opposite direction as well. These results establish a proof of principle: They show that stochastic pumps are able to mimic the behavior of nonequilibrium steady states, and vice versa, within the theoretical framework of discrete-state stochastic thermodynamics. Nonequilibrium steady states and stochastic pumps are often used to model, respectively, biomolecular motors driven by chemical reactions and artificial molecular machines steered by the variation of external, macroscopic parameters. Our results loosely suggest that anything a biomolecular machine can do, an artificial molecular machine can do equally well. We illustrate this principle by showing that kinetic proofreading, a NESS mechanism that explains the low error rates in biochemical reactions, can be effectively mimicked by a constrained periodic driving.

  13. (abstract) Short Time Period Variations in Jupiter's Synchrotron Radiation

    NASA Technical Reports Server (NTRS)

    Bolton, S. J.; Klein, M. J.; Gulkis, S.; Foster, R.; Heiles, C.; Pater, I. de

    1994-01-01

    The long term time variability of Jupiter's synchrotron radiation on yearly time scales has been established for some time. For many years, theorists have speculated about the effects variations in the solar wind, solar flux, Io, the Io torus, and Jupiter's magnetic field have on the ultra-relativistic electron population responsible for the emission. Early observational results suggested the additional possibility of a short term time variability, on timescales of days to weeks. In 1989 a program designed to investigate the existence of short term time variability using the 85 foot Hat Creek radio telescope operating at 1400 MHz was initiated. The availability of a dedicated telescope provided the opportunity, for the first time, to obtain numerous observations over the full Jupiter rotation period. These and future observations will enable two important studies, characterization and confirmation of possible short term variations, and the investigation of the stability of Jupiter's synchrotron emission beaming curve. Analysis of Hat Creek observations and early results from the Maryland Point Naval research Laboratory will be presented.

  14. Langevin Dynamics with Space-Time Periodic Nonequilibrium Forcing

    NASA Astrophysics Data System (ADS)

    Joubaud, R.; Pavliotis, G. A.; Stoltz, G.

    2015-01-01

    We present results on the ballistic and diffusive behavior of the Langevin dynamics in a periodic potential that is driven away from equilibrium by a space-time periodic driving force, extending some of the results obtained by Collet and Martinez in (J Math Biol, 56(6):765-792 2008). In the hyperbolic scaling, a nontrivial average velocity can be observed even if the external forcing vanishes in average. More surprisingly, an average velocity in the direction opposite to the forcing may develop at the linear response level—a phenomenon called negative mobility. The diffusive limit of the non-equilibrium Langevin dynamics is also studied using the general methodology of central limit theorems for additive functionals of Markov processes. To apply this methodology, which is based on the study of appropriate Poisson equations, we extend recent results on pointwise estimates of the resolvent of the generator associated with the Langevin dynamics. Our theoretical results are illustrated by numerical simulations of a two-dimensional system.

  15. Desensitization to media violence over a short period of time.

    PubMed

    Fanti, Kostas A; Vanman, Eric; Henrich, Christopher C; Avraamides, Marios N

    2009-01-01

    This study investigated the desensitization to violence over a short period of time. Participants watched nine violent movie scenes and nine comedy scenes, and reported whether they enjoyed the violent or comedy scenes and whether they felt sympathetic toward the victim of violence. Using latent growth modeling, analyses were carried out to investigate how participants responded to the different scenes across time. The findings of this study suggested that repeated exposure to media violence reduces the psychological impact of media violence in the short term, therefore desensitizing viewers to media violence. As a result, viewers tended to feel less sympathetic toward the victims of violence and actually enjoy more the violence portrayed in the media. Additionally, desensitization to media violence was better represented by a curvilinear pattern, whereas desensitization to comedy scenes was better represented by a linear pattern. Finally, trait aggression was not related to the pattern of change over time, although significant effects were found for initial reports of enjoyment and sympathy. PMID:19172659

  16. Swimming and transport of bacteria in time-periodic flows

    NASA Astrophysics Data System (ADS)

    Winter, Rebecca; Patteson, Alison; Gagnon, David; Arratia, Paulo

    The transport of bacteria can be highly influenced by external flows in oceans, rivers, and intestinal tracts. This has implications in biological systems for the performance of major biological processes, such as biofilm formation. In this study, we experimentally investigate the aggregation and transport of swimming Vibrio cholerae bacteria in time-periodic flows. Bacteria are placed in a well-characterized flow, and bacterial concentrations are recorded for a range of Reynolds numbers (Re) that spans two orders of magnitude, from 0.1 to 10. It is generally found that bacteria deplete from regions of high deformation rate and accumulate near vortices. This phenomenon seems to be dictated by a combination of bacterial activity and background flow vorticity. R.W. supported by NSF-GRFP.

  17. Relaxation Characteristics of 828 DGEBA Epoxy Over Long Time Periods

    NASA Astrophysics Data System (ADS)

    Hoo, Jasmine; Reprogle, Riley C.; Wisler, Brian; Arechederra, Gabriel K.; McCoy, John D.; Kropka, Jamie M.; Long, Kevin N.

    The mechanical relaxation response in uniaxial compression of a diglycidyl ether of bisphenol-A epoxy was studied over long time periods. The epoxy, 828DEA, was Epon 828 cured with diethanolamine (DEA). A sample was compressed at constant strain rate and held at various strain levels for days to allow the sample to relax. The sample was then compressed further and held once more. The relaxation curves were fit with a stretched exponential function. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL85000.

  18. Navy Global Predictions for the Dynamo Time Period

    NASA Astrophysics Data System (ADS)

    Reynolds, C. A.; Ridout, J. A.; Flatau, M. K.; Chen, J.; Richman, J. G.; Jensen, T. G.; Shriver, J. F.

    2014-12-01

    The performance of 30-day simulations of the Navy Global Environmental Model (NAVGEM) is evaluated under several metrics. The time period of interest is the DYNAMO (Dynamics of Madden Julian Oscillation) field experiment period, starting late October 2011. The NAVGEM experiments are run at an effective 37-km resolution with several different SST configurations. The in the first set of experiments, the initial SST analysis, provided by the NCODA (Navy Coupled Ocean Data Assimilation) system, is either held fixed to the initial value (fixed SST) or updated every 6 hours. These forecasts are compared with forecasts in which the SST is updated with 3-h analyses from the Hybrid Coordinate Ocean Model (HYCOM), and forecasts in which NAVGEM is interactively coupled to HYCOM. Experiments are also performed with different physical parameterization options. The extended integrations are verified using observed OLR, TRMM precipitation estimates, and global analyses. The use of fixed SSTs is clearly sub-optimal. Biases in monthly mean fields are far more pronounced in the simulations where the SST is held fixed as compared to those in simulations where updated SST analyses are used. Biases in the monthly mean fields are further reduced when NAVGEM is coupled to HYCOM. Differences in SST can "migrate" to substantial changes in the time-mean land-surface temperatures, illustrating the substantial impact of SSTs over the full domain. Concerning the simulation of the MJO, some improvement is noted when the system is fully coupled, although the simulations still exhibit deficiencies such as eastward propagation that is too slow, and difficulty propagating over the maritime continent. Simulations that are started every 5 days indicate that the NAVGEM uncoupled system has difficulty predicting MJO initiation, but simulations started when the MJO is active in the Indian Ocean are able to capture eastward propagation characteristics. The coupled NAVGEM-HYCOM system shows ability to

  19. 14 CFR 221.190 - Time for filing and computation of time periods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Time for filing and computation of time periods. 221.190 Section 221.190 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS TARIFFS Electronically Filed Tariffs § 221.190...

  20. 14 CFR 221.190 - Time for filing and computation of time periods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Time for filing and computation of time periods. 221.190 Section 221.190 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS TARIFFS Electronically Filed Tariffs § 221.190...

  1. 12 CFR 116.10 - How does the OCC compute time periods under this part?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... commences the time period. When the last day of a time period is a Saturday, Sunday, or Federal holiday, the time period runs until the end of the next day that is not a Saturday, Sunday, or Federal holiday....

  2. 12 CFR 116.10 - How does the OCC compute time periods under this part?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... commences the time period. When the last day of a time period is a Saturday, Sunday, or Federal holiday, the time period runs until the end of the next day that is not a Saturday, Sunday, or Federal holiday....

  3. Adaptive stabilization of discrete-time systems using linear periodically time varying controllers

    NASA Technical Reports Server (NTRS)

    Ortega, Romeo; Albertos, Pedro; Lozano, Rogelio

    1988-01-01

    A direct adaptive scheme based on the use of linear time-varying periodic controllers is proposed which estimates online the periodic coefficients of the controller. It is shown that adaptive stabilization is attained for all possibly nonstably invertible plants of known order but unknown delay. Although no appeal is made to persistency of excitation arguments, a provision is needed to avoid the singularity of an estimated matrix, this property being required only for the analysis and not the control calculations.

  4. Infrared Time Lags for the Periodic Quasar PG 1302-102

    NASA Astrophysics Data System (ADS)

    Jun, Hyunsung D.; Stern, Daniel; Graham, Matthew J.; Djorgovski, S. G.; Mainzer, Amy; Cutri, Roc M.; Drake, Andrew J.; Mahabal, Ashish A.

    2015-11-01

    The optical light curve of the quasar PG 1302-102 at z=0.278 shows a strong, smooth 5.2 year periodic signal, detectable over a period of ∼20 years. Although the interpretation of this phenomenon is still uncertain, the most plausible mechanisms involve a binary system of two supermassive black holes with a subparsec separation. At this close separation, the nuclear black holes in PG 1302-102 will likely merge within ∼ {10}5 years due to gravitational wave emission alone. Here, we report the rest-frame near-infrared time lags for PG 1302-102. Compiling data from WISE and Akari, we confirm that the periodic behavior reported in the optical light curve from Graham et al. is reproduced at infrared wavelengths, with best-fit observed-frame 3.4 and 4.6 μ {{m}} time lags of (2219 ± 153, 2408 ± 148) days for a near face-on orientation of the torus, or (4103 ± 153, 4292 ± 148) days for an inclined system with relativistic Doppler boosting in effect. The periodicity in the infrared light curves and the light-travel time of the accretion disk photons to reach the dust glowing regions support that a source within the accretion disk is responsible for the optical variability of PG 1302-102, echoed at the farther out dusty regions. The implied distance of this dusty, assumed toroidal region is ∼1.5 pc for a near face-on geometry or ∼1.1 pc for the relativistic Doppler-boosted case.

  5. Social Development:: 2 Year Olds

    MedlinePlus

    ... Español Text Size Email Print Share Social Development: 2 Year Olds Page Content Article Body By nature, ... probably are acting the same way. At age two, children view the world almost exclusively through their ...

  6. Language Development: 2 Year Olds

    MedlinePlus

    ... Stages Listen Español Text Size Email Print Share Language Development: 2 Year Olds Page Content Article Body ... Pay attention to how he also is using language to describe ideas and information and to express ...

  7. Convergence Time towards Periodic Orbits in Discrete Dynamical Systems

    PubMed Central

    San Martín, Jesús; Porter, Mason A.

    2014-01-01

    We investigate the convergence towards periodic orbits in discrete dynamical systems. We examine the probability that a randomly chosen point converges to a particular neighborhood of a periodic orbit in a fixed number of iterations, and we use linearized equations to examine the evolution near that neighborhood. The underlying idea is that points of stable periodic orbit are associated with intervals. We state and prove a theorem that details what regions of phase space are mapped into these intervals (once they are known) and how many iterations are required to get there. We also construct algorithms that allow our theoretical results to be implemented successfully in practice. PMID:24736594

  8. Convergence time towards periodic orbits in discrete dynamical systems.

    PubMed

    San Martín, Jesús; Porter, Mason A

    2014-01-01

    We investigate the convergence towards periodic orbits in discrete dynamical systems. We examine the probability that a randomly chosen point converges to a particular neighborhood of a periodic orbit in a fixed number of iterations, and we use linearized equations to examine the evolution near that neighborhood. The underlying idea is that points of stable periodic orbit are associated with intervals. We state and prove a theorem that details what regions of phase space are mapped into these intervals (once they are known) and how many iterations are required to get there. We also construct algorithms that allow our theoretical results to be implemented successfully in practice.

  9. Convergence time towards periodic orbits in discrete dynamical systems.

    PubMed

    San Martín, Jesús; Porter, Mason A

    2014-01-01

    We investigate the convergence towards periodic orbits in discrete dynamical systems. We examine the probability that a randomly chosen point converges to a particular neighborhood of a periodic orbit in a fixed number of iterations, and we use linearized equations to examine the evolution near that neighborhood. The underlying idea is that points of stable periodic orbit are associated with intervals. We state and prove a theorem that details what regions of phase space are mapped into these intervals (once they are known) and how many iterations are required to get there. We also construct algorithms that allow our theoretical results to be implemented successfully in practice. PMID:24736594

  10. Logic Model Checking of Time-Periodic Real-Time Systems

    NASA Technical Reports Server (NTRS)

    Florian, Mihai; Gamble, Ed; Holzmann, Gerard

    2012-01-01

    In this paper we report on the work we performed to extend the logic model checker SPIN with built-in support for the verification of periodic, real-time embedded software systems, as commonly used in aircraft, automobiles, and spacecraft. We first extended the SPIN verification algorithms to model priority based scheduling policies. Next, we added a library to support the modeling of periodic tasks. This library was used in a recent application of the SPIN model checker to verify the engine control software of an automobile, to study the feasibility of software triggers for unintended acceleration events.

  11. Burning invariant manifolds in time-periodic and time-aperiodic vortex flows

    NASA Astrophysics Data System (ADS)

    Gowen, Savannah; Solomon, Tom

    2014-11-01

    We present experiments that study reaction fronts in a flow composed of a single, translating vortex. The fronts are produced by the excitable Belousov-Zhabotinsky (BZ) chemical reaction, and the vortex flow is driven magnetohydrodynamically by a radial current in a thin fluid layer above a Nd-Fe-Bo magnet. The magnet is mounted on a pair of perpendicular translation stages, allowing for controlled, two-dimensional movement of the magnet and the resulting vortex. We study reaction fronts that pin to the vortex for time-independent flows (produced by moving the vortex with a constant velocity) and for time-periodic and time-aperiodic flows produced by oscillating the vortex laterally. The steady-state front shape is analyzed in terms of burning invariant manifolds (BIMs) that act as one-way barriers against any propagating reaction fronts. For time independent and time-periodic flows, the location of the BIMs are calculated numerically and are compared with experimental images of the pinned reaction fronts. We investigate extensions of this BIM approach for analyzing fronts in time-aperiodic flows. Supported by NSF Grants DMR-1004744, DMR-1361881 and PHY-1156964.

  12. 29 CFR 4000.43 - How do I compute a time period?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false How do I compute a time period? 4000.43 Section 4000.43..., ISSUANCE, COMPUTATION OF TIME, AND RECORD RETENTION Computation of Time § 4000.43 How do I compute a time period? (a) In general. If you are computing a time period to which this part applies, whether you...

  13. Unsettled Times, Unsettled Prices: Periodical Price Survey 1997.

    ERIC Educational Resources Information Center

    Ketcham, Lee; Born, Kathleen

    1997-01-01

    Presents the results of the thirty-seventh annual periodical price survey conducted by "Library Journal". Highlights include canceling print subscriptions and electronic journals, cost trends by subject and by countries, prices for public and school libraries and for college and medium-sized university libraries, and budgeting for 1988. (LRW)

  14. Using travel times to simulate multi-dimensional bioreactive transport in time-periodic flows.

    PubMed

    Sanz-Prat, Alicia; Lu, Chuanhe; Finkel, Michael; Cirpka, Olaf A

    2016-04-01

    In travel-time models, the spatially explicit description of reactive transport is replaced by associating reactive-species concentrations with the travel time or groundwater age at all locations. These models have been shown adequate for reactive transport in river-bank filtration under steady-state flow conditions. Dynamic hydrological conditions, however, can lead to fluctuations of infiltration velocities, putting the validity of travel-time models into question. In transient flow, the local travel-time distributions change with time. We show that a modified version of travel-time based reactive transport models is valid if only the magnitude of the velocity fluctuates, whereas its spatial orientation remains constant. We simulate nonlinear, one-dimensional, bioreactive transport involving oxygen, nitrate, dissolved organic carbon, aerobic and denitrifying bacteria, considering periodic fluctuations of velocity. These fluctuations make the bioreactive system pulsate: The aerobic zone decreases at times of low velocity and increases at those of high velocity. For the case of diurnal fluctuations, the biomass concentrations cannot follow the hydrological fluctuations and a transition zone containing both aerobic and obligatory denitrifying bacteria is established, whereas a clear separation of the two types of bacteria prevails in the case of seasonal velocity fluctuations. We map the 1-D results to a heterogeneous, two-dimensional domain by means of the mean groundwater age for steady-state flow in both domains. The mapped results are compared to simulation results of spatially explicit, two-dimensional, advective-dispersive-bioreactive transport subject to the same relative fluctuations of velocity as in the one-dimensional model. The agreement between the mapped 1-D and the explicit 2-D results is excellent. We conclude that travel-time models of nonlinear bioreactive transport are adequate in systems of time-periodic flow if the flow direction does not change.

  15. Using travel times to simulate multi-dimensional bioreactive transport in time-periodic flows

    NASA Astrophysics Data System (ADS)

    Sanz-Prat, Alicia; Lu, Chuanhe; Finkel, Michael; Cirpka, Olaf A.

    2016-04-01

    In travel-time models, the spatially explicit description of reactive transport is replaced by associating reactive-species concentrations with the travel time or groundwater age at all locations. These models have been shown adequate for reactive transport in river-bank filtration under steady-state flow conditions. Dynamic hydrological conditions, however, can lead to fluctuations of infiltration velocities, putting the validity of travel-time models into question. In transient flow, the local travel-time distributions change with time. We show that a modified version of travel-time based reactive transport models is valid if only the magnitude of the velocity fluctuates, whereas its spatial orientation remains constant. We simulate nonlinear, one-dimensional, bioreactive transport involving oxygen, nitrate, dissolved organic carbon, aerobic and denitrifying bacteria, considering periodic fluctuations of velocity. These fluctuations make the bioreactive system pulsate: The aerobic zone decreases at times of low velocity and increases at those of high velocity. For the case of diurnal fluctuations, the biomass concentrations cannot follow the hydrological fluctuations and a transition zone containing both aerobic and obligatory denitrifying bacteria is established, whereas a clear separation of the two types of bacteria prevails in the case of seasonal velocity fluctuations. We map the 1-D results to a heterogeneous, two-dimensional domain by means of the mean groundwater age for steady-state flow in both domains. The mapped results are compared to simulation results of spatially explicit, two-dimensional, advective-dispersive-bioreactive transport subject to the same relative fluctuations of velocity as in the one-dimensional model. The agreement between the mapped 1-D and the explicit 2-D results is excellent. We conclude that travel-time models of nonlinear bioreactive transport are adequate in systems of time-periodic flow if the flow direction does not change.

  16. Existence, Uniqueness and Asymptotic Stability of Time Periodic Traveling Waves for a Periodic Lotka-Volterra Competition System with Diffusion.

    PubMed

    Zhao, Guangyu; Ruan, Shigui

    2011-06-01

    We study the existence, uniqueness, and asymptotic stability of time periodic traveling wave solutions to a periodic diffusive Lotka-Volterra competition system. Under certain conditions, we prove that there exists a maximal wave speed c(*) such that for each wave speed c ≤ c(*), there is a time periodic traveling wave connecting two semi-trivial periodic solutions of the corresponding kinetic system. It is shown that such a traveling wave is unique modulo translation and is monotone with respect to its co-moving frame coordinate. We also show that the traveling wave solutions with wave speed c < c(*) are asymptotically stable in certain sense. In addition, we establish the nonexistence of time periodic traveling waves for nonzero speed c > c(*).

  17. Existence, Uniqueness and Asymptotic Stability of Time Periodic Traveling Waves for a Periodic Lotka-Volterra Competition System with Diffusion.

    PubMed

    Zhao, Guangyu; Ruan, Shigui

    2011-06-01

    We study the existence, uniqueness, and asymptotic stability of time periodic traveling wave solutions to a periodic diffusive Lotka-Volterra competition system. Under certain conditions, we prove that there exists a maximal wave speed c(*) such that for each wave speed c ≤ c(*), there is a time periodic traveling wave connecting two semi-trivial periodic solutions of the corresponding kinetic system. It is shown that such a traveling wave is unique modulo translation and is monotone with respect to its co-moving frame coordinate. We also show that the traveling wave solutions with wave speed c < c(*) are asymptotically stable in certain sense. In addition, we establish the nonexistence of time periodic traveling waves for nonzero speed c > c(*). PMID:21572575

  18. Periodization

    PubMed Central

    Lorenz, Daniel S.; Reiman, Michael P.; Walker, John C.

    2010-01-01

    Background: Clinicians are constantly faced with the challenge of designing training programs for injured and noninjured athletes that maximize healing and optimize performance. Periodization is a concept of systematic progression—that is, resistance training programs that follow predictable patterns of change in training variables. The strength training literature is abundant with studies comparing periodization schemes on uninjured, trained, and untrained athletes. The rehabilitation literature, however, is scarce with information about how to optimally design resistance training programs based on periodization principles for injured athletes. The purpose of this review is to discuss relevant training variables and methods of periodization, as well as periodization program outcomes. A secondary purpose is to provide an anecdotal framework regarding implementation of periodization principles into rehabilitation programs. Evidence Acquisition: A Medline search from 1979 to 2009 was implemented with the keywords periodization, strength training, rehabilitation, endurance, power, hypertrophy, and resistance training with the Boolean term AND in all possible combinations in the English language. Each author also undertook independent hand searching of article references used in this review. Results: Based on the studies researched, periodized strength training regimens demonstrate improved outcomes as compared to nonperiodized programs. Conclusions: Despite the evidence in the strength training literature supporting periodization programs, there is a considerable lack of data in the rehabilitation literature about program design and successful implementation of periodization into rehabilitation programs. PMID:23015982

  19. Controlling mixing and segregation in time periodic granular flows

    NASA Astrophysics Data System (ADS)

    Bhattacharya, Tathagata

    Segregation is a major problem for many solids processing industries. Differences in particle size or density can lead to flow-induced segregation. In the present work, we employ the discrete element method (DEM)---one type of particle dynamics (PD) technique---to investigate the mixing and segregation of granular material in some prototypical solid handling devices, such as a rotating drum and chute. In DEM, one calculates the trajectories of individual particles based on Newton's laws of motion by employing suitable contact force models and a collision detection algorithm. Recently, it has been suggested that segregation in particle mixers can be thwarted if the particle flow is inverted at a rate above a critical forcing frequency. Further, it has been hypothesized that, for a rotating drum, the effectiveness of this technique can be linked to the probability distribution of the number of times a particle passes through the flowing layer per rotation of the drum. In the first portion of this work, various configurations of solid mixers are numerically and experimentally studied to investigate the conditions for improved mixing in light of these hypotheses. Besides rotating drums, many studies of granular flow have focused on gravity driven chute flows owing to its practical importance in granular transportation and to the fact that the relative simplicity of this type of flow allows for development and testing of new theories. In this part of the work, we observe the deposition behavior of both mono-sized and polydisperse dry granular materials in an inclined chute flow. The effects of different parameters such as chute angle, particle size, falling height and charge amount on the mass fraction distribution of granular materials after deposition are investigated. The simulation results obtained using DEM are compared with the experimental findings and a high degree of agreement is observed. Tuning of the underlying contact force parameters allows the achievement

  20. Emotional Development: 2 Year Olds

    MedlinePlus

    ... Español Text Size Email Print Share Emotional Development: 2 Year Olds Page Content Article Body It’s so ... to follow the ups and downs of a two-year-old. One moment he’s beaming and friendly; ...

  1. 16 CFR 1502.2 - Computation of time periods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... officer, or by the Commission, Saturdays, Sundays, and Federal holidays are included in computing time. However, if the last day for taking such action falls on a Saturday, Sunday, or Federal holiday,...

  2. 16 CFR 1502.2 - Computation of time periods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... officer, or by the Commission, Saturdays, Sundays, and Federal holidays are included in computing time. However, if the last day for taking such action falls on a Saturday, Sunday, or Federal holiday,...

  3. The nature of species interactions shifts profoundly between time periods

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Species interactions change through time, for example ontogenetically, successionally, and evolutionarily. They also change as environmental conditions change, both within years (seasonally) and between years (year effects). The former are relatively well-studied, but the latter have received less a...

  4. Load Balancing Using Time Series Analysis for Soft Real Time Systems with Statistically Periodic Loads

    NASA Technical Reports Server (NTRS)

    Hailperin, Max

    1993-01-01

    This thesis provides design and analysis of techniques for global load balancing on ensemble architectures running soft-real-time object-oriented applications with statistically periodic loads. It focuses on estimating the instantaneous average load over all the processing elements. The major contribution is the use of explicit stochastic process models for both the loading and the averaging itself. These models are exploited via statistical time-series analysis and Bayesian inference to provide improved average load estimates, and thus to facilitate global load balancing. This thesis explains the distributed algorithms used and provides some optimality results. It also describes the algorithms' implementation and gives performance results from simulation. These results show that our techniques allow more accurate estimation of the global system load ing, resulting in fewer object migration than local methods. Our method is shown to provide superior performance, relative not only to static load-balancing schemes but also to many adaptive methods.

  5. Quasi-Periodic Oscillations: Energy Dependent Time-lags

    NASA Astrophysics Data System (ADS)

    Misra, R.; Mandal, S.

    2014-07-01

    We present a a generic model for alternating lags in QPO harmonics where variations in the photon spectrum are caused by oscillations in two parameters that characterize the spectrum. The model assumes that variations in one of the parameters are linearly driven by variations in the other after a time delay. We show that alternating lags will be observed for a range of time delays. We have further developed a phenomenological model based on this generic one that can explain the amplitude and phase lag variation with energy of the fundamental and the next three harmonics of the 67 mHz QPO observed in GRS 1915+105. The phenomenological model also predicts the variation of the Bicoherence phase with energy, which can be checked by further analysis of the observational data.

  6. 14 CFR 135.273 - Duty period limitations and rest time requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Duty period limitations and rest time requirements. 135.273 Section 135.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Crewmember Flight Time and Duty Period Limitations and Rest Requirements § 135.273 Duty period...

  7. 14 CFR 135.273 - Duty period limitations and rest time requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Duty period limitations and rest time requirements. 135.273 Section 135.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Crewmember Flight Time and Duty Period Limitations and Rest Requirements § 135.273 Duty period...

  8. 14 CFR 135.273 - Duty period limitations and rest time requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Duty period limitations and rest time requirements. 135.273 Section 135.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Crewmember Flight Time and Duty Period Limitations and Rest Requirements § 135.273 Duty period...

  9. 14 CFR 135.273 - Duty period limitations and rest time requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Duty period limitations and rest time requirements. 135.273 Section 135.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Crewmember Flight Time and Duty Period Limitations and Rest Requirements § 135.273 Duty period...

  10. 14 CFR 135.273 - Duty period limitations and rest time requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Duty period limitations and rest time requirements. 135.273 Section 135.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Crewmember Flight Time and Duty Period Limitations and Rest Requirements § 135.273 Duty period...

  11. The timing behavior of magnetar Swift J1822.3-1606: timing noise or a decreasing period derivative?

    NASA Astrophysics Data System (ADS)

    Tong, Hao; Xu, Ren-Xin

    2013-10-01

    The different timing results of the magnetar Swift J1822.3-1606 are analyzed and understood theoretically. It is noted that different timing solutions are caused not only by timing noise, but also because the period derivative is decreasing after the outburst. Both the decreasing period derivative and the large timing noise may originate from wind braking associated with the magnetar. Future timing of Swift J1822.3-1606 will help clarify whether or not its period derivative is decreasing with time.

  12. 45 CFR 402.26 - Time period for obligation and expenditure of grant funds.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CFR 92.23(b). This time limit will not be extended. The time limit established by 45 CFR 92.23(b) does... STATE LEGALIZATION IMPACT ASSISTANCE GRANTS Administration of Grants § 402.26 Time period for...

  13. 20 CFR 404.996 - Increase in future benefits where time period for reopening expires.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Increase in future benefits where time period for reopening expires. 404.996 Section 404.996 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... § 404.996 Increase in future benefits where time period for reopening expires. If, after the time...

  14. Comparative evaluation of real-time PCR and conventional RT-PCR during a 2 year surveillance for influenza and respiratory syncytial virus among children with acute respiratory infections in Kolkata, India, reveals a distinct seasonality of infection.

    PubMed

    Agrawal, Anurodh S; Sarkar, Mehuli; Chakrabarti, Sekhar; Rajendran, K; Kaur, Harpreet; Mishra, Akhilesh C; Chatterjee, Mrinal K; Naik, Trailokya N; Chadha, Mandeep S; Chawla-Sarkar, Mamta

    2009-12-01

    Acute respiratory tract infections (ARTIs) are one of the most common causes of morbidity and mortality in young children worldwide. Influenza virus and respiratory syncytial virus (RSV) are the predominant aetiological agents during seasonal epidemics, and thus rapid and sensitive molecular tests for screening for such agents and timely identification of epidemics are required. This study compared real-time quantitative PCR (qPCR) with conventional RT-PCR for parallel identification of influenza A virus (IAV) or influenza B virus (IBV) and RSV. A total of 1091 respiratory samples was examined from children with suspected ARTIs between January 2007 and December 2008. Of these, 275 (25.21 %) were positive for either influenza or RSV by qPCR compared with 262 (24 .01%) positive by RT-PCR. Overall, IAV, IBV and RSV were detected in 121 (11.09 %), 59 (5.41 %) and 95 (8.71 %) samples, respectively. In spite of overlapping clinical symptoms, RSV and influenza virus showed distinct seasonal peaks. IAV correlated positively and RSV negatively with rainfall and temperature. No distinct seasonality was observed in IBV infections. This is, to the best of our knowledge, the first report of a systemic surveillance of respiratory viruses with seasonal correlation and prevalence rates from eastern India. This 2 year comparative analysis also confirmed the feasibility of using qPCR in developing countries, which will not only improve the scope for prevention of epidemics, but will also provide crucial epidemiological data from tropical regions.

  15. Structure and dating errors in the geologic time scale and periodicity in mass extinctions

    NASA Technical Reports Server (NTRS)

    Stothers, Richard B.

    1989-01-01

    Structure in the geologic time scale reflects a partly paleontological origin. As a result, ages of Cenozoic and Mesozoic stage boundaries exhibit a weak 28-Myr periodicity that is similar to the strong 26-Myr periodicity detected in mass extinctions of marine life by Raup and Sepkoski. Radiometric dating errors in the geologic time scale, to which the mass extinctions are stratigraphically tied, do not necessarily lessen the likelihood of a significant periodicity in mass extinctions, but do spread the acceptable values of the period over the range 25-27 Myr for the Harland et al. time scale or 25-30 Myr for the DNAG time scale. If the Odin time scale is adopted, acceptable periods fall between 24 and 33 Myr, but are not robust against dating errors. Some indirect evidence from independently-dated flood-basalt volcanic horizons tends to favor the Odin time scale.

  16. Dynamics of phase slips in systems with time-periodic modulation

    NASA Astrophysics Data System (ADS)

    Gandhi, Punit; Knobloch, Edgar; Beaume, Cédric

    2015-12-01

    The Adler equation with time-periodic frequency modulation is studied. A series of resonances between the period of the frequency modulation and the time scale for the generation of a phase slip is identified. The resulting parameter space structure is determined using a combination of numerical continuation, time simulations, and asymptotic methods. Regions with an integer number of phase slips per period are separated by regions with noninteger numbers of phase slips and include canard trajectories that drift along unstable equilibria. Both high- and low-frequency modulation is considered. An adiabatic description of the low-frequency modulation regime is found to be accurate over a large range of modulation periods.

  17. 5 CFR 550.404 - Computation of advance payments and evacuation payments; time periods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... evacuation payments; time periods. 550.404 Section 550.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY ADMINISTRATION (GENERAL) Payments During Evacuation § 550.404 Computation of advance payments and evacuation payments; time periods. (a) Payments shall be based on the...

  18. 5 CFR 550.404 - Computation of advance payments and evacuation payments; time periods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... evacuation payments; time periods. 550.404 Section 550.404 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY ADMINISTRATION (GENERAL) Payments During Evacuation § 550.404 Computation of advance payments and evacuation payments; time periods. (a) Payments shall be based on the...

  19. 47 CFR 54.724 - Time periods for Commission approval of Administrator decisions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Time periods for Commission approval of Administrator decisions. 54.724 Section 54.724 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Review of Decisions Issued by the Administrator § 54.724 Time periods for...

  20. 47 CFR 54.724 - Time periods for Commission approval of Administrator decisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Time periods for Commission approval of...) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Review of Decisions Issued by the Administrator § 54.724 Time periods for Commission approval of Administrator decisions. (a) The Wireline...

  1. 47 CFR 54.724 - Time periods for Commission approval of Administrator decisions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Time periods for Commission approval of...) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Review of Decisions Issued by the Administrator § 54.724 Time periods for Commission approval of Administrator decisions. (a) The Wireline...

  2. 47 CFR 54.724 - Time periods for Commission approval of Administrator decisions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Time periods for Commission approval of...) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Review of Decisions Issued by the Administrator § 54.724 Time periods for Commission approval of Administrator decisions. (a) The Wireline...

  3. 47 CFR 54.724 - Time periods for Commission approval of Administrator decisions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Time periods for Commission approval of...) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Review of Decisions Issued by the Administrator § 54.724 Time periods for Commission approval of Administrator decisions. (a) The Wireline...

  4. 12 CFR 516.10 - How does OTS compute time periods under this part?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false How does OTS compute time periods under this part? 516.10 Section 516.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES § 516.10 How does OTS compute time periods under this part? In...

  5. 12 CFR 516.10 - How does OTS compute time periods under this part?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS compute time periods under this part? 516.10 Section 516.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES § 516.10 How does OTS compute time periods under this part? In...

  6. 17 CFR 260.7a-24 - Words relating to periods of time in the past.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Words relating to periods of time in the past. 260.7a-24 Section 260.7a-24 Commodity and Securities Exchanges SECURITIES AND... Requirements As to Contents § 260.7a-24 Words relating to periods of time in the past. Unless the...

  7. 29 CFR 4000.43 - How do I compute a time period?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false How do I compute a time period? 4000.43 Section 4000.43..., ISSUANCE, COMPUTATION OF TIME, AND RECORD RETENTION Computation of Time § 4000.43 How do I compute a time... backwards. Suppose you are required to file an advance notice of reportable event for a transaction that...

  8. 29 CFR 4000.43 - How do I compute a time period?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false How do I compute a time period? 4000.43 Section 4000.43..., ISSUANCE, COMPUTATION OF TIME, AND RECORD RETENTION Computation of Time § 4000.43 How do I compute a time... backwards. Suppose you are required to file an advance notice of reportable event for a transaction that...

  9. Period, epoch, and prediction errors of ephemerides from continuous sets of timing measurements

    NASA Astrophysics Data System (ADS)

    Deeg, H. J.

    2015-06-01

    Space missions such as Kepler and CoRoT have led to large numbers of eclipse or transit measurements in nearly continuous time series. This paper shows how to obtain the period error in such measurements from a basic linear least-squares fit, and how to correctly derive the timing error in the prediction of future transit or eclipse events. Assuming strict periodicity, a formula for the period error of these time series is derived, σP = σT (12 / (N3-N))1 / 2, where σP is the period error, σT the timing error of a single measurement, and N the number of measurements. Compared to the iterative method for period error estimation by Mighell & Plavchan (2013), this much simpler formula leads to smaller period errors, whose correctness has been verified through simulations. For the prediction of times of future periodic events, usual linear ephemeris were epoch errors are quoted for the first time measurement, are prone to an overestimation of the error of that prediction. This may be avoided by a correction for the duration of the time series. An alternative is the derivation of ephemerides whose reference epoch and epoch error are given for the centre of the time series. For long continuous or near-continuous time series whose acquisition is completed, such central epochs should be the preferred way for the quotation of linear ephemerides. While this work was motivated from the analysis of eclipse timing measures in space-based light curves, it should be applicable to any other problem with an uninterrupted sequence of discrete timings for which the determination of a zero point, of a constant period and of the associated errors is needed.

  10. 40 CFR 93.162 - Emissions beyond the time period covered by the SIP.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... covered by the SIP. 93.162 Section 93.162 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 93.162 Emissions beyond the time period covered by the SIP. If a Federal action would result in total... period covered by the SIP, the Federal agency can: (a) Demonstrate conformity with the last...

  11. 40 CFR 93.162 - Emissions beyond the time period covered by the SIP.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... covered by the SIP. 93.162 Section 93.162 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 93.162 Emissions beyond the time period covered by the SIP. If a Federal action would result in total... period covered by the SIP, the Federal agency can: (a) Demonstrate conformity with the last...

  12. 45 CFR 402.26 - Time period for obligation and expenditure of grant funds.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CFR 92.23(b). This time limit will not be extended. The time limit established by 45 CFR 92.23(b) does... 45 Public Welfare 2 2011-10-01 2011-10-01 false Time period for obligation and expenditure of grant funds. 402.26 Section 402.26 Public Welfare Regulations Relating to Public Welfare OFFICE...

  13. 45 CFR 402.26 - Time period for obligation and expenditure of grant funds.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CFR 92.23(b). This time limit will not be extended. The time limit established by 45 CFR 92.23(b) does... 45 Public Welfare 2 2014-10-01 2012-10-01 true Time period for obligation and expenditure of grant funds. 402.26 Section 402.26 Public Welfare Regulations Relating to Public Welfare OFFICE OF...

  14. Existence and exponential stability of positive almost periodic solution for Nicholson's blowflies models on time scales.

    PubMed

    Li, Yongkun; Li, Bing

    2016-01-01

    In this paper, we first give a new definition of almost periodic time scales, two new definitions of almost periodic functions on time scales and investigate some basic properties of them. Then, as an application, by using a fixed point theorem in Banach space and the time scale calculus theory, we obtain some sufficient conditions for the existence and exponential stability of positive almost periodic solutions for a class of Nicholson's blowflies models on time scales. Finally, we present an illustrative example to show the effectiveness of obtained results. Our results show that under a simple condition the continuous-time Nicholson's blowflies model and its discrete-time analogue have the same dynamical behaviors. PMID:27468397

  15. An infinite branching hierarchy of time-periodic solutions of the Benjamin-Ono equation

    SciTech Connect

    Wilkening, Jon

    2008-07-01

    We present a new representation of solutions of the Benjamin-Ono equation that are periodic in space and time. Up to an additive constant and a Galilean transformation, each of these solutions is a previously known, multi-periodic solution; however, the new representation unifies the subset of such solutions with a fixed spatial period and a continuously varying temporal period into a single network of smooth manifolds connected together by an infinite hierarchy of bifurcations. Our representation explicitly describes the evolution of the Fourier modes of the solution as well as the particle trajectories in a meromorphic representation of these solutions; therefore, we have also solved the problem of finding periodic solutions of the ordinary differential equation governing these particles, including a description of a bifurcation mechanism for adding or removing particles without destroying periodicity. We illustrate the types of bifurcation that occur with several examples, including degenerate bifurcations not predicted by linearization about traveling waves.

  16. Dynamics of phase slips in systems with time-periodic modulation.

    PubMed

    Gandhi, Punit; Knobloch, Edgar; Beaume, Cédric

    2015-12-01

    The Adler equation with time-periodic frequency modulation is studied. A series of resonances between the period of the frequency modulation and the time scale for the generation of a phase slip is identified. The resulting parameter space structure is determined using a combination of numerical continuation, time simulations, and asymptotic methods. Regions with an integer number of phase slips per period are separated by regions with noninteger numbers of phase slips and include canard trajectories that drift along unstable equilibria. Both high- and low-frequency modulation is considered. An adiabatic description of the low-frequency modulation regime is found to be accurate over a large range of modulation periods. PMID:26764781

  17. Non-Markovian diffusion over a potential barrier in the presence of periodic time modulation

    SciTech Connect

    Kolomietz, V. M.; Radionov, S. V.

    2011-11-15

    The diffusive non-Markovian motion over a single-well potential barrier in the presence of a weak sinusoidal time modulation is studied. We found nonmonotonic dependence of the mean escape time from the barrier on a frequency of the periodic modulation that is analogous to the stochastic resonance phenomenon. The resonant increase of diffusion over the barrier occurs at the frequency inversely proportional to the mean first-passage time for the motion in the absence of the time modulation.

  18. Time Lapse Hydrogeophysical Monitoring of Near Surface Processes over Long Time Periods

    NASA Astrophysics Data System (ADS)

    Endres, A.; Beynon, A.; Hansen, J.; Toy, C.; Steelman, C. M.

    2012-12-01

    The capacity to provide non-invasive time lapse monitoring that gives valuable insight into complex near-surface processes is a well-recognized attribute of hydrogeophysical techniques. Many of the studies using time lapse hydrogeophysical monitoring have been done for durations ranging from a day to several months. However, the nature of these processes can significantly change over the annual cycle of hydrological conditions. Hence, studies using time lapse hydrogeophysical monitoring for duration of one or more annual cycles are needed to investigate these longer term effects. The hydrogeophysics group at the University of Waterloo has undertaken an extensive series of field studies using high-resolution geophysical techniques to monitor several annual cycles of shallow soil moisture dynamics typical in temperate climates. In this work, our group have been employing a variety of geoelectrical methods, such as electrical resistivity tomography (ERT), ground conductivity meters (GCM) and high-frequency (i.e., 225-900 MHz) ground penetrating radar (GPR). In particular, we have investigated the ability of these geoelectrical methods to characterize both the vertical soil moisture distribution within the shallow vadose zone and the nature of its coupling with soil moisture variations at the surface. Our results clearly demonstrate the ability of these geoelectrical methods to characterize the evolution of near-surface hydrological processes over the annual cycle. In particular, we have been able to perform detailed monitoring of winter freeze-thaw processes which have major hydrological impacts in temperate regions. Further, our multi-year data sets have allowed us to investigate variation in hydrological processes between contrasting annual cycles (e.g., wet versus dry summer conditions).

  19. A framework for periodic outlier pattern detection in time-series sequences.

    PubMed

    Rasheed, Faraz; Alhajj, Reda

    2014-05-01

    Periodic pattern detection in time-ordered sequences is an important data mining task, which discovers in the time series all patterns that exhibit temporal regularities. Periodic pattern mining has a large number of applications in real life; it helps understanding the regular trend of the data along time, and enables the forecast and prediction of future events. An interesting related and vital problem that has not received enough attention is to discover outlier periodic patterns in a time series. Outlier patterns are defined as those which are different from the rest of the patterns; outliers are not noise. While noise does not belong to the data and it is mostly eliminated by preprocessing, outliers are actual instances in the data but have exceptional characteristics compared with the majority of the other instances. Outliers are unusual patterns that rarely occur, and, thus, have lesser support (frequency of appearance) in the data. Outlier patterns may hint toward discrepancy in the data such as fraudulent transactions, network intrusion, change in customer behavior, recession in the economy, epidemic and disease biomarkers, severe weather conditions like tornados, etc. We argue that detecting the periodicity of outlier patterns might be more important in many sequences than the periodicity of regular, more frequent patterns. In this paper, we present a robust and time efficient suffix tree-based algorithm capable of detecting the periodicity of outlier patterns in a time series by giving more significance to less frequent yet periodic patterns. Several experiments have been conducted using both real and synthetic data; all aspects of the proposed approach are compared with the existing algorithm InfoMiner; the reported results demonstrate the effectiveness and applicability of the proposed approach.

  20. Finding hidden periodic signals in time series - an application to stock prices

    NASA Astrophysics Data System (ADS)

    O'Shea, Michael

    2014-03-01

    Data in the form of time series appear in many areas of science. In cases where the periodicity is apparent and the only other contribution to the time series is stochastic in origin, the data can be `folded' to improve signal to noise and this has been done for light curves of variable stars with the folding resulting in a cleaner light curve signal. Stock index prices versus time are classic examples of time series. Repeating patterns have been claimed by many workers and include unusually large returns on small-cap stocks during the month of January, and small returns on the Dow Jones Industrial average (DJIA) in the months June through September compared to the rest of the year. Such observations imply that these prices have a periodic component. We investigate this for the DJIA. If such a component exists it is hidden in a large non-periodic variation and a large stochastic variation. We show how to extract this periodic component and for the first time reveal its yearly (averaged) shape. This periodic component leads directly to the `Sell in May and buy at Halloween' adage. We also drill down and show that this yearly variation emerges from approximately half of the underlying stocks making up the DJIA index.

  1. Rank One Strange Attractors in Periodically Kicked Predator-Prey System with Time-Delay

    NASA Astrophysics Data System (ADS)

    Yang, Wenjie; Lin, Yiping; Dai, Yunxian; Zhao, Huitao

    2016-06-01

    This paper is devoted to the study of the problem of rank one strange attractor in a periodically kicked predator-prey system with time-delay. Our discussion is based on the theory of rank one maps formulated by Wang and Young. Firstly, we develop the rank one chaotic theory to delayed systems. It is shown that strange attractors occur when the delayed system undergoes a Hopf bifurcation and encounters an external periodic force. Then we use the theory to the periodically kicked predator-prey system with delay, deriving the conditions for Hopf bifurcation and rank one chaos along with the results of numerical simulations.

  2. Area Spectrum of Btz Black Holes from the Periodicity in Euclidean Time

    NASA Astrophysics Data System (ADS)

    Larrañaga, Alexis

    2012-08-01

    In this paper, we analyze the area spectrum of BTZ three-dimensional black holes by considering an outgoing wave and relating its period of motion with the period of the gravitational system with respect to Euclidean time. The area spectra obtained for the rotating and non-rotating black holes are equally spaced and it is important to note that in this paper, we do not need to use the small angular momentum assumption which is necessary in the quasinormal mode approach for rotating black holes. The results suggest that the periodicity of the black hole gravitational system may be the origin of area quantization.

  3. Identification of periods of clear sky irradiance in time series of GHI measurements

    DOE PAGES

    Reno, Matthew J.; Hansen, Clifford W.

    2016-01-18

    In this study, we present a simple algorithm for identifying periods of time with broadband global horizontal irradiance (GHI) similar to that occurring during clear sky conditions from a time series of GHI measurements. Other available methods to identify these periods do so by identifying periods with clear sky conditions using additional measurements, such as direct or diffuse irradiance. Our algorithm compares characteristics of the time series of measured GHI with the output of a clear sky model without requiring additional measurements. We validate our algorithm using data from several locations by comparing our results with those obtained from amore » clear sky detection algorithm, and with satellite and ground-based sky imagery.« less

  4. Reproductive numbers for nonautonomous spatially distributed periodic SIS models acting on two time scales.

    PubMed

    Marvá, M; Bravo de la Parra, R; Auger, P

    2012-06-01

    In this work we deal with a general class of spatially distributed periodic SIS epidemic models with two time scales. We let susceptible and infected individuals migrate between patches with periodic time dependent migration rates. The existence of two time scales in the system allows to describe certain features of the asymptotic behavior of its solutions with the help of a less dimensional, aggregated, system. We derive global reproduction numbers governing the general spatially distributed nonautonomous system through the aggregated system. We apply this result when the mass action law and the frequency dependent transmission law are considered. Comparing these global reproductive numbers to their non spatially distributed counterparts yields the following: adequate periodic migration rates allow global persistence or eradication of epidemics where locally, in absence of migrations, the contrary is expected.

  5. Periodic trim solutions with hp-version finite elements in time

    NASA Technical Reports Server (NTRS)

    Peters, David A.; Hou, Lin-Jun

    1990-01-01

    Finite elements in time as an alternative strategy for rotorcraft trim problems are studied. The research treats linear flap and linearized flap-lag response both for quasi-trim and trim cases. The connection between Fourier series analysis and hp-finite elements for periodic a problem is also examined. It is proved that Fourier series is a special case of space-time finite elements in which one element is used with a strong displacement formulation. Comparisons are made with respect to accuracy among Fourier analysis, displacement methods, and mixed methods over a variety parameters. The hp trade-off is studied for the periodic trim problem to provide an optimum step size and order of polynomial for a given error criteria. It is found that finite elements in time can outperform Fourier analysis for periodic problems, and for some given error criteria. The mixed method provides better results than does the displacement method.

  6. People's preference patterns for gains/losses in multiple time period situations.

    PubMed

    Chang, Shin-Shin; Chang, Jung-Hua

    2013-10-01

    Little research to date has been devoted to investigating whether people treat time differently from money when facing multiple gains or losses. This study tested the hypothesis that because time is characterized by perishability, fixed supply, and infungibility, people with strong motivation to obtain a long period of uninterrupted discretionary time would strive to trim the time needed for non-discretionary activities or to combine several non-discretionary activities. As a result, people prefer integration over segregation of multiple time losses or gains, which is not consistent with the prediction based on hedonic editing theory or the renewable resource model. This proposition is supported by results from four experiments.

  7. People's preference patterns for gains/losses in multiple time period situations.

    PubMed

    Chang, Shin-Shin; Chang, Jung-Hua

    2013-10-01

    Little research to date has been devoted to investigating whether people treat time differently from money when facing multiple gains or losses. This study tested the hypothesis that because time is characterized by perishability, fixed supply, and infungibility, people with strong motivation to obtain a long period of uninterrupted discretionary time would strive to trim the time needed for non-discretionary activities or to combine several non-discretionary activities. As a result, people prefer integration over segregation of multiple time losses or gains, which is not consistent with the prediction based on hedonic editing theory or the renewable resource model. This proposition is supported by results from four experiments. PMID:24597454

  8. Adaptive time-delayed stabilization of steady states and periodic orbits.

    PubMed

    Selivanov, Anton; Lehnert, Judith; Fradkov, Alexander; Schöll, Eckehard

    2015-01-01

    We derive adaptive time-delayed feedback controllers that stabilize fixed points and periodic orbits. First, we develop an adaptive controller for stabilization of a steady state by applying the speed-gradient method to an appropriate goal function and prove global asymptotic stability of the resulting system. For an example we show that the advantage of the adaptive controller over the nonadaptive one is in a smaller controller gain. Second, we propose adaptive time-delayed algorithms for stabilization of periodic orbits. Their efficiency is confirmed by local stability analysis. Numerical examples demonstrate the applicability of the proposed controllers.

  9. A Time-Delayed Mathematical Model for Tumor Growth with the Effect of a Periodic Therapy.

    PubMed

    Xu, Shihe; Wei, Xiangqing; Zhang, Fangwei

    2016-01-01

    A time-delayed mathematical model for tumor growth with the effect of periodic therapy is studied. The establishment of the model is based on the reaction-diffusion dynamics and mass conservation law and is considered with a time delay in cell proliferation process. Sufficient conditions for the global stability of tumor free equilibrium are given. We also prove that if external concentration of nutrients is large the tumor will not disappear and the conditions under which there exist periodic solutions to the model are also determined. Results are illustrated by computer simulations.

  10. A Time-Delayed Mathematical Model for Tumor Growth with the Effect of a Periodic Therapy

    PubMed Central

    Xu, Shihe; Wei, Xiangqing; Zhang, Fangwei

    2016-01-01

    A time-delayed mathematical model for tumor growth with the effect of periodic therapy is studied. The establishment of the model is based on the reaction-diffusion dynamics and mass conservation law and is considered with a time delay in cell proliferation process. Sufficient conditions for the global stability of tumor free equilibrium are given. We also prove that if external concentration of nutrients is large the tumor will not disappear and the conditions under which there exist periodic solutions to the model are also determined. Results are illustrated by computer simulations. PMID:27274763

  11. A Time-Delayed Mathematical Model for Tumor Growth with the Effect of a Periodic Therapy.

    PubMed

    Xu, Shihe; Wei, Xiangqing; Zhang, Fangwei

    2016-01-01

    A time-delayed mathematical model for tumor growth with the effect of periodic therapy is studied. The establishment of the model is based on the reaction-diffusion dynamics and mass conservation law and is considered with a time delay in cell proliferation process. Sufficient conditions for the global stability of tumor free equilibrium are given. We also prove that if external concentration of nutrients is large the tumor will not disappear and the conditions under which there exist periodic solutions to the model are also determined. Results are illustrated by computer simulations. PMID:27274763

  12. Developmental critical windows and sensitive periods as three-dimensional constructs in time and space.

    PubMed

    Burggren, Warren W; Mueller, Casey A

    2015-01-01

    A critical window (sensitive period) represents a period during development when an organism's phenotype is responsive to intrinsic or extrinsic (environmental) factors. Such windows represent a form of developmental phenotypic plasticity and result from the interaction between genotype and environment. Critical windows have typically been defined as comprising discrete periods in development with a distinct starting time and end time, as identified by experiments following an on and an off protocol. Yet in reality, periods of responsiveness during development are likely more ambiguous that depicted. Our goal is to extend the concept of the developmental critical window by introducing a three-dimensional construct in which time during development, dose of the stressor applied, and the resultant phenotypic modification can be utilized to more realistically define a critical window. Using the example of survival of the brine shrimp (Artemia franciscana) during exposure to different salinity levels during development, we illustrate that it is not just stressor dose or exposure time but the interaction of these two factors that results in the measured phenotypic change, which itself may vary within a critical window. We additionally discuss a systems approach to critical windows, in which the components of a developing system--whether they be molecular, physiological, or morphological--may show differing responses with respect to time and dose. Thus, the plasticity of each component may contribute to a broader overall system response. PMID:25730265

  13. Acute increases in night-time plasma melatonin levels following a period of meditation.

    PubMed

    Tooley, G A; Armstrong, S M; Norman, T R; Sali, A

    2000-05-01

    To determine whether a period of meditation could influence melatonin levels, two groups of meditators were tested in a repeated measures design for changes in plasma melatonin levels at midnight. Experienced meditators practising either TM-Sidhi or another internationally well known form of yoga showed significantly higher plasma melatonin levels in the period immediately following meditation compared with the same period at the same time on a control night. It is concluded that meditation, at least in the two forms studied here, can affect plasma melatonin levels. It remains to be determined whether this is achieved through decreased hepatic metabolism of the hormone or via a direct effect on pineal physiology. Either way, facilitation of higher physiological melatonin levels at appropriate times of day might be one avenue through which the claimed health promoting effects of meditation occur.

  14. Periodic bifurcation of Duffing-van der Pol oscillators having fractional derivatives and time delay

    NASA Astrophysics Data System (ADS)

    Leung, A. Y. T.; Yang, H. X.; Zhu, P.

    2014-04-01

    In this paper, a Duffing-van der Pol oscillator having fractional derivatives and time delays is investigated by the residue harmonic method. The angular frequencies and limit cycles of periodic motions are expanded into a power series of an order-tracking parameter and the unbalanced residues resulting from the truncated Fourier series are considered iteratively to improve the accuracy. The periodic bifurcations are examined using the fractional order, feedback gain and time delay as continuation parameters. It is shown that jumps and hysteresis phenomena can be delayed or removed. Transition from discontinuous bifurcation to continuous bifurcation is observed. The approximations are verified by numerical integration. We find that the proposed method can easily be programmed and can predict accurate periodic approximations while the system parameters being unfolded.

  15. Molecular response properties from a Hermitian eigenvalue equation for a time-periodic Hamiltonian

    NASA Astrophysics Data System (ADS)

    Pawłowski, Filip; Olsen, Jeppe; Jørgensen, Poul

    2015-03-01

    The time-dependent Schrödinger equation for a time-periodic perturbation is recasted into a Hermitian eigenvalue equation, where the quasi-energy is an eigenvalue and the time-periodic regular wave function an eigenstate. From this Hermitian eigenvalue equation, a rigorous and transparent formulation of response function theory is developed where (i) molecular properties are defined as derivatives of the quasi-energy with respect to perturbation strengths, (ii) the quasi-energy can be determined from the time-periodic regular wave function using a variational principle or via projection, and (iii) the parametrization of the unperturbed state can differ from the parametrization of the time evolution of this state. This development brings the definition of molecular properties and their determination on par for static and time-periodic perturbations and removes inaccuracies and inconsistencies of previous response function theory formulations. The development where the parametrization of the unperturbed state and its time evolution may differ also extends the range of the wave function models for which response functions can be determined. The simplicity and universality of the presented formulation is illustrated by applying it to the configuration interaction (CI) and the coupled cluster (CC) wave function models and by introducing a new model—the coupled cluster configuration interaction (CC-CI) model—where a coupled cluster exponential parametrization is used for the unperturbed state and a linear parametrization for its time evolution. For static perturbations, the CC-CI response functions are shown to be the analytical analogues of the static molecular properties obtained from finite field equation-of-motion coupled cluster (EOMCC) energy calculations. The structural similarities and differences between the CI, CC, and CC-CI response functions are also discussed with emphasis on linear versus non-linear parametrizations and the size-extensivity of the

  16. A Gaussian Process Based Online Change Detection Algorithm for Monitoring Periodic Time Series

    SciTech Connect

    Chandola, Varun; Vatsavai, Raju

    2011-01-01

    Online time series change detection is a critical component of many monitoring systems, such as space and air-borne remote sensing instruments, cardiac monitors, and network traffic profilers, which continuously analyze observations recorded by sensors. Data collected by such sensors typically has a periodic (seasonal) component. Most existing time series change detection methods are not directly applicable to handle such data, either because they are not designed to handle periodic time series or because they cannot operate in an online mode. We propose an online change detection algorithm which can handle periodic time series. The algorithm uses a Gaussian process based non-parametric time series prediction model and monitors the difference between the predictions and actual observations within a statistically principled control chart framework to identify changes. A key challenge in using Gaussian process in an online mode is the need to solve a large system of equations involving the associated covariance matrix which grows with every time step. The proposed algorithm exploits the special structure of the covariance matrix and can analyze a time series of length T in O(T^2) time while maintaining a O(T) memory footprint, compared to O(T^4) time and O(T^2) memory requirement of standard matrix manipulation methods. We experimentally demonstrate the superiority of the proposed algorithm over several existing time series change detection algorithms on a set of synthetic and real time series. Finally, we illustrate the effectiveness of the proposed algorithm for identifying land use land cover changes using Normalized Difference Vegetation Index (NDVI) data collected for an agricultural region in Iowa state, USA. Our algorithm is able to detect different types of changes in a NDVI validation data set (with ~80% accuracy) which occur due to crop type changes as well as disruptive changes (e.g., natural disasters).

  17. Identifying the Critical Time Period for Information Extraction when Recognizing Sequences of Play

    ERIC Educational Resources Information Center

    North, Jamie S.; Williams, A. Mark

    2008-01-01

    The authors attempted to determine the critical time period for information extraction when recognizing play sequences in soccer. Although efforts have been made to identify the perceptual information underpinning such decisions, no researchers have attempted to determine "when" this information may be extracted from the display. The authors…

  18. The Role of Thermal Properties in Periodic Time-Varying Phenomena

    ERIC Educational Resources Information Center

    Marin, E.

    2007-01-01

    The role played by physical parameters governing the transport of heat in periodical time-varying phenomena within solids is discussed. Starting with a brief look at the conduction heat transport mechanism, the equations governing heat conduction under static, stationary and non-stationary conditions, and the physical parameters involved, are…

  19. Real-time control of the period of individual ELMs by EC power on TCV

    NASA Astrophysics Data System (ADS)

    Felici, F.; Rossel, J. X.; Duval, B. P.; Coda, S.; Goodman, T. P.; Martin, Y.; Moret, J.-M.; Sauter, O.; the TCV Team

    2013-11-01

    The period of individual type-I edge-localized modes (ELMs) in TCV H-mode plasmas is controlled by real-time controlled application of electron cyclotron (EC) power close to the plasma pedestal. An ELM pacing algorithm, closely related to sawtooth pacing (Goodman et al (2011 Phys. Rev. Lett. 106 245002)) has been implemented in the TCV control system. This algorithm switches the EC power to a low level after detecting an ELM, and subsequently increases the power to a higher level after a pre-set time interval, stimulating the advent of the next ELM. While the mean ELM period is observed to depend only on the mean power applied, ELM pacing is shown to significantly regularize the ELM period with respect to the case of continuously applied power. It is also shown that the ELM period can be changed from one ELM to the next on time scales shorter than the global energy confinement time. These results present a challenging benchmark to physics-based pedestal models and can point towards obtaining a deeper understanding of the physics of individual ELM cycles.

  20. 19 CFR 351.524 - Allocation of benefit to a particular time period.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Allocation of benefit to a particular time period. 351.524 Section 351.524 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE... support payments; discounts on electricity, water, and other utilities; freight subsidies;...

  1. 9 CFR 201.217 - Reasonable period of time to remedy a breach of contract.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Reasonable period of time to remedy a breach of contract. 201.217 Section 201.217 Animals and Animal Products GRAIN INSPECTION, PACKERS AND... contract or agreement where food safety or animal welfare is concerned. These criteria, include, but...

  2. 41 CFR 105-8.150-3 - Time period for compliance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Time period for compliance. 105-8.150-3 Section 105-8.150-3 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 8-ENFORCEMENT OF...

  3. 41 CFR 105-8.150-3 - Time period for compliance.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Time period for compliance. 105-8.150-3 Section 105-8.150-3 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 8-ENFORCEMENT OF...

  4. 41 CFR 105-8.150-3 - Time period for compliance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Time period for compliance. 105-8.150-3 Section 105-8.150-3 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 8-ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS...

  5. 41 CFR 105-8.150-3 - Time period for compliance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Time period for compliance. 105-8.150-3 Section 105-8.150-3 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 8-ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS...

  6. 18 CFR 290.103 - Time of filing and reporting period.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Time of filing and reporting period. 290.103 Section 290.103 Conservation of Power and Water Resources FEDERAL ENERGY... 1978 COLLECTION OF COST OF SERVICE INFORMATION UNDER SECTION 133 OF THE PUBLIC UTILITY...

  7. 18 CFR 290.103 - Time of filing and reporting period.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Time of filing and reporting period. 290.103 Section 290.103 Conservation of Power and Water Resources FEDERAL ENERGY... 1978 COLLECTION OF COST OF SERVICE INFORMATION UNDER SECTION 133 OF THE PUBLIC UTILITY...

  8. 9 CFR 201.217 - Reasonable period of time to remedy a breach of contract.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Reasonable period of time to remedy a breach of contract. 201.217 Section 201.217 Animals and Animal Products GRAIN INSPECTION, PACKERS AND... termination. These criteria do not limit a packer, swine contractor or live poultry dealer's rights under...

  9. 9 CFR 201.217 - Reasonable period of time to remedy a breach of contract.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Reasonable period of time to remedy a breach of contract. 201.217 Section 201.217 Animals and Animal Products GRAIN INSPECTION, PACKERS AND... termination. These criteria do not limit a packer, swine contractor or live poultry dealer's rights under...

  10. 42 CFR 87.7 - For what period of time will grants be awarded?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false For what period of time will grants be awarded? 87.7 Section 87.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY...

  11. 5 CFR 550.404 - Computation of advance payments and evacuation payments; time periods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Computation of advance payments and... Computation of advance payments and evacuation payments; time periods. (a) Payments shall be based on the rate... others, when applicable, shall be made before advance payments or evacuation payments are made....

  12. 5 CFR 550.404 - Computation of advance payments and evacuation payments; time periods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Computation of advance payments and... Computation of advance payments and evacuation payments; time periods. (a) Payments shall be based on the rate... others, when applicable, shall be made before advance payments or evacuation payments are made....

  13. Forum Page Letters in the "Straits Times" of Singapore during Relatively Free and Restricted Press Periods.

    ERIC Educational Resources Information Center

    Ramaprasad, Jyotika; Ong, James

    In order to identify the scope or limits of the practice of development journalism, a study examined the content of the Forum page in the "Straits Times" of Singapore during relatively free (1979-1980) and restricted (1986-1987) press periods. The study had two major objectives: (1) to study the nature of the Forum page (a readers' letter page in…

  14. Practitioners' Perceptions of the Soccer Extra-Time Period: Implications for Future Research.

    PubMed

    Harper, Liam D; Fothergill, Melissa; West, Daniel J; Stevenson, Emma; Russell, Mark

    2016-01-01

    Qualitative research investigating soccer practitioners' perceptions can allow researchers to create practical research investigations. The extra-time period of soccer is understudied compared to other areas of soccer research. Using an open-ended online survey containing eleven main and nine sub questions, we gathered the perceptions of extra-time from 46 soccer practitioners, all working for different professional soccer clubs. Questions related to current practices, views on extra-time regulations, and ideas for future research. Using inductive content analysis, the following general dimensions were identified: 'importance of extra-time', 'rule changes', 'efficacy of extra-time hydro-nutritional provision', 'nutritional timing', 'future research directions', 'preparatory modulations' and 'recovery'. The majority of practitioners (63%) either agreed or strongly agreed that extra-time is an important period for determining success in knockout football match-play. When asked if a fourth substitution should be permitted in extra-time, 67% agreed. The use of hydro-nutritional strategies prior to extra-time was predominately considered important or very important. However; only 41% of practitioners felt that it was the most important time point for the use of nutritional products. A similar number of practitioners account (50%) and do not (50%) account for the potential of extra-time when training and preparing players and 89% of practitioners stated that extra-time influences recovery practices following matches. In the five minute break prior to extra-time, the following practices (in order of priority) were advocated to players: hydration, energy provision, massage, and tactical preparations. Additionally, 87% of practitioners advocate a particular nutritional supplementation strategy prior to extra-time. In order of importance, practitioners see the following as future research areas: nutritional interventions, fatigue responses, acute injury risk, recovery

  15. Practitioners' Perceptions of the Soccer Extra-Time Period: Implications for Future Research.

    PubMed

    Harper, Liam D; Fothergill, Melissa; West, Daniel J; Stevenson, Emma; Russell, Mark

    2016-01-01

    Qualitative research investigating soccer practitioners' perceptions can allow researchers to create practical research investigations. The extra-time period of soccer is understudied compared to other areas of soccer research. Using an open-ended online survey containing eleven main and nine sub questions, we gathered the perceptions of extra-time from 46 soccer practitioners, all working for different professional soccer clubs. Questions related to current practices, views on extra-time regulations, and ideas for future research. Using inductive content analysis, the following general dimensions were identified: 'importance of extra-time', 'rule changes', 'efficacy of extra-time hydro-nutritional provision', 'nutritional timing', 'future research directions', 'preparatory modulations' and 'recovery'. The majority of practitioners (63%) either agreed or strongly agreed that extra-time is an important period for determining success in knockout football match-play. When asked if a fourth substitution should be permitted in extra-time, 67% agreed. The use of hydro-nutritional strategies prior to extra-time was predominately considered important or very important. However; only 41% of practitioners felt that it was the most important time point for the use of nutritional products. A similar number of practitioners account (50%) and do not (50%) account for the potential of extra-time when training and preparing players and 89% of practitioners stated that extra-time influences recovery practices following matches. In the five minute break prior to extra-time, the following practices (in order of priority) were advocated to players: hydration, energy provision, massage, and tactical preparations. Additionally, 87% of practitioners advocate a particular nutritional supplementation strategy prior to extra-time. In order of importance, practitioners see the following as future research areas: nutritional interventions, fatigue responses, acute injury risk, recovery

  16. Reliability of Fitness Tests Using Methods and Time Periods Common in Sport and Occupational Management

    PubMed Central

    Burnstein, Bryan D.; Steele, Russell J.; Shrier, Ian

    2011-01-01

    Context: Fitness testing is used frequently in many areas of physical activity, but the reliability of these measurements under real-world, practical conditions is unknown. Objective: To evaluate the reliability of specific fitness tests using the methods and time periods used in the context of real-world sport and occupational management. Design: Cohort study. Setting: Eighteen different Cirque du Soleil shows. Patients or Other Participants: Cirque du Soleil physical performers who completed 4 consecutive tests (6-month intervals) and were free of injury or illness at each session (n = 238 of 701 physical performers). Intervention(s): Performers completed 6 fitness tests on each assessment date: dynamic balance, Harvard step test, handgrip, vertical jump, pull-ups, and 60-second jump test. Main Outcome Measure(s): We calculated the intraclass coefficient (ICC) and limits of agreement between baseline and each time point and the ICC over all 4 time points combined. Results: Reliability was acceptable (ICC > 0.6) over an 18-month time period for all pairwise comparisons and all time points together for the handgrip, vertical jump, and pull-up assessments. The Harvard step test and 60-second jump test had poor reliability (ICC < 0.6) between baseline and other time points. When we excluded the baseline data and calculated the ICC for 6-month, 12-month, and 18-month time points, both the Harvard step test and 60-second jump test demonstrated acceptable reliability. Dynamic balance was unreliable in all contexts. Limit-of-agreement analysis demonstrated considerable intraindividual variability for some tests and a learning effect by administrators on others. Conclusions: Five of the 6 tests in this battery had acceptable reliability over an 18-month time frame, but the values for certain individuals may vary considerably from time to time for some tests. Specific tests may require a learning period for administrators. PMID:22488138

  17. Time-space Variability of Weekly to Monthly Period Equatorial Waves in the Pacific Ocean

    NASA Astrophysics Data System (ADS)

    Durland, T.; Farrar, J. T.

    2015-12-01

    Data from satellite altimetry are used to characterize wavelike variability in the tropical Pacific Ocean at periods of days to two months. This period band is of interest because the space-time scales of oceanic equatorial waves at these frequencies have historically made adequate observation of the variability difficult. These waves have zonal scales that are very large (exceeding 3000 km) and meridional scales that are relatively short (~100 km), making in situ measurements difficult, and the short temporal scales pose challenges for observation with satellite altimeters because the wave periods are short compared to orbit repeat periods. As a result, there has been relatively little progress since the early 1980s in characterizing and understanding these equatorial inertia-gravity and mixed Rossby-gravity waves. In this analysis, we seek to exploit the long zonal length scales of these high-frequency equatorial waves in an analysis of satellite scatterometer and altimeter data to shed new light on the properties and dynamics of these waves. At periods of 2-14 days, there is clear evidence for the presence of several basin-scale equatorial wave modes, including mixed Rossby-gravity waves and inertia-gravity waves associated with baroclinic modes one and two. Here, we focus on equatorial Kelvin waves and mixed Rossby-gravity waves forced in the western Pacific, and examine their variability in time and space and their relation to wind.

  18. The Varying Light Curve and Timings of the Ultrashort-period Contact Binary KIC 9532219

    NASA Astrophysics Data System (ADS)

    Lee, Jae Woo; Hong, Kyeongsoo; Koo, Jae-Rim; Park, Jang-Ho

    2016-03-01

    KIC 9532219 is a W UMa-type eclipsing binary with an orbital period of 0.1981549 days that is below the short-period limit (˜0.22 days) of the period distribution for contact binaries. The Kepler light curve of the system exhibits striking changes in both eclipse depths and light maxima. Applying third-body and spot effects, the light-curve synthesis indicates that the eclipsing pair is currently in a marginal contact stage with a mass ratio of q = 1.20, an orbital inclination of i = 66.°0, a temperature difference of T1-T2 = 172 K, and a third light of l3 = 75.9%. To understand the light variations with time, we divided up the light curve into 312 segments and analyzed them separately. The results reveal that variation of eclipse depth is primarily caused by changing amounts of contamination due to the nearby star KIC 9532228 between the Kepler Quarters and that the variable O’Connell effect originates from the starspot activity on the less massive primary component. Based on our light-curve timings, a period study of KIC 9532219 indicates that the orbital period has varied as a combination of a downward parabola and a light-travel-time (LTT) effect due to a third body, which has a period of 1196 days and a minimum mass of 0.0892 M⊙ in an orbit of eccentricity 0.150. The parabolic variation could be a small part of a second LTT orbit due to a fourth component in a wider orbit, instead of either mass transfer or angular momentum loss.

  19. Child Mortality Estimation: Appropriate Time Periods for Child Mortality Estimates from Full Birth Histories

    PubMed Central

    Pedersen, Jon; Liu, Jing

    2012-01-01

    Background Child mortality estimates from complete birth histories from Demographic and Health Surveys (DHS) surveys and similar surveys are a chief source of data used to track Millennium Development Goal 4, which aims for a reduction of under-five mortality by two-thirds between 1990 and 2015. Based on the expected sample sizes when the DHS program commenced, the estimates are usually based on 5-y time periods. Recent surveys have had larger sample sizes than early surveys, and here we aimed to explore the benefits of using shorter time periods than 5 y for estimation. We also explore the benefit of changing the estimation procedure from being based on years before the survey, i.e., measured with reference to the date of the interview for each woman, to being based on calendar years. Methods and Findings Jackknife variance estimation was used to calculate standard errors for 207 DHS surveys in order to explore to what extent the large samples in recent surveys can be used to produce estimates based on 1-, 2-, 3-, 4-, and 5-y periods. We also recalculated the estimates for the surveys into calendar-year-based estimates. We demonstrate that estimation for 1-y periods is indeed possible for many recent surveys. Conclusions The reduction in bias achieved using 1-y periods and calendar-year-based estimation is worthwhile in some cases. In particular, it allows tracking of the effects of particular events such as droughts, epidemics, or conflict on child mortality in a way not possible with previous estimation procedures. Recommendations to use estimation for short time periods when possible and to use calendar-year-based estimation were adopted in the United Nations 2011 estimates of child mortality. PMID:22952435

  20. Effects of combined linear and nonlinear periodic training on physical fitness and competition times in finswimmers

    PubMed Central

    Yu, Kyung-Hun; Suk, Min-Hwa; Kang, Shin-Woo; Shin, Yun-A

    2014-01-01

    The purpose of this study was to investigate the effect of combined linear and nonlinear periodic training on physical fitness and competition times in finswimmers. The linear resistance training model (6 days/week) and nonlinear underwater training (4 days/week) were applied to 12 finswimmers (age, 16.08± 1.44 yr; career, 3.78± 1.90 yr) for 12 weeks. Body composition measures included weight, body mass index (BMI), percent fat, and fat-free mass. Physical fitness measures included trunk flexion forward, trunk extension backward, sargent jump, 1-repetition-maximum (1 RM) squat, 1 RM dead lift, knee extension, knee flexion, trunk extension, trunk flexion, and competition times. Body composition and physical fitness were improved after the 12-week periodic training program. Weight, BMI, and percent fat were significantly decreased, and trunk flexion forward, trunk extension backward, sargent jump, 1 RM squat, 1 RM dead lift, and knee extension (right) were significantly increased. The 50- and 100-m times significantly decreased in all 12 athletes. After 12 weeks of training, all finswimmers who participated in this study improved their times in a public competition. These data indicate that combined linear and nonlinear periodic training enhanced the physical fitness and competition times in finswimmers. PMID:25426469

  1. The effect of entrainment on the timing of periodic eye movements.

    PubMed

    Richardson, Brian A; Balasubramaniam, Ramesh

    2010-01-18

    We performed an experiment in which eight healthy individuals made periodic eye movements at five pacing interval conditions (500 ms, 750 ms, 1000 ms, 1250 ms, and 1500 ms). Three methods of entrainment were used in the synchronization phase: saccade, continuous pursuit and discontinuous pursuit. The stimulus train was extinguished and in the continuation phase, subjects made saccadic eye movements at the entrained movement frequencies between two static targets. Using the Wing-Kristofferson model, clock and motor variance were extracted from the time series of continuation trials for all three entrainment conditions. Our results revealed a main effect of time interval on total variance clock variance (as predicted by Weber's law) and on motor variance. We also report that the pursuit entrainment conditions resulted in and mean duration and variance to the saccade entrainment. These results suggest that the neural networks recruited to support a periodic motor timing task depend on the method used to establish the temporal reference.

  2. Periodic trim solutions with HP-version finite elements in time

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Finite Element in Time has been proven to be a powerful alternative solving strategy for the rotor craft trim problem. Additionally, Finite Element Method in Time has been developed in various versions like time-marching framework, Galerkin framework, Rayleigh-Ritz framework, and mixed formulation. Recently, this method was applied to the rotorcraft trim problem to obtain linearized solutions. The rotorcraft trim problem consists of trying to find a period solution for period-coefficient, differential equations subject to side constraints where certain force and momentum balance equations are forced to be equal to zero. There are free (or trim) parameters that are chosen to meet these side constraints. This project aims at expanding the application, in terms of the rotorcraft trim problem, from a linearized solution to nonlinear solution.

  3. Association of intrinsic circadian period with morningness-eveningness, usual wake time, and circadian phase

    NASA Technical Reports Server (NTRS)

    Duffy, J. F.; Rimmer, D. W.; Czeisler, C. A.

    2001-01-01

    The biological basis of preferences for morning or evening activity patterns ("early birds" and "night owls") has been hypothesized but has remained elusive. The authors reported that, compared with evening types, the circadian pacemaker of morning types was entrained to an earlier hour with respect to both clock time and wake time. The present study explores a chronobiological mechanism by which the biological clock of morning types may be set to an earlier hour. Intrinsic period, a fundamental property of the circadian system, was measured in a month-long inpatient study. A subset of participants also had their circadian phase assessed. Participants completed a morningness-eveningness questionnaire before study. Circadian period was correlated with morningness-eveningness, circadian phase, and wake time, demonstrating that a fundamental property of the circadian pacemaker is correlated with the behavioral trait of morningness-eveningness.

  4. Estimating Periodic Software Rejuvenation Schedules under Discrete-Time Operation Circumstance

    NASA Astrophysics Data System (ADS)

    Iwamoto, Kazuki; Dohi, Tadashi; Kaio, Naoto

    Software rejuvenation is a preventive and proactive solution that is particularly useful for counteracting the phenomenon of software aging. In this article, we consider periodic software rejuvenation models based on the expected cost per unit time in the steady state under discrete-time operation circumstance. By applying the discrete renewal reward processes, we describe the stochastic behavior of a telecommunication billing application with a degradation mode, and determine the optimal periodic software rejuvenation schedule minimizing the expected cost. Similar to the earlier work by the same authors, we develop a statistically non-parametric algorithm to estimate the optimal software rejuvenation schedule, by applying the discrete total time on test concept. Numerical examples are presented to estimate the optimal software rejuvenation schedules from the simulation data. We discuss the asymptotic behavior of estimators developed in this paper.

  5. Sex difference in the near-24-hour intrinsic period of the human circadian timing system

    PubMed Central

    Duffy, Jeanne F.; Cain, Sean W.; Chang, Anne-Marie; Phillips, Andrew J. K.; Münch, Mirjam Y.; Gronfier, Claude; Wyatt, James K.; Dijk, Derk-Jan; Czeisler, Charles A.

    2011-01-01

    The circadian rhythms of melatonin and body temperature are set to an earlier hour in women than in men, even when the women and men maintain nearly identical and consistent bedtimes and wake times. Moreover, women tend to wake up earlier than men and exhibit a greater preference for morning activities than men. Although the neurobiological mechanism underlying this sex difference in circadian alignment is unknown, multiple studies in nonhuman animals have demonstrated a sex difference in circadian period that could account for such a difference in circadian alignment between women and men. Whether a sex difference in intrinsic circadian period in humans underlies the difference in circadian alignment between men and women is unknown. We analyzed precise estimates of intrinsic circadian period collected from 157 individuals (52 women, 105 men; aged 18–74 y) studied in a month-long inpatient protocol designed to minimize confounding influences on circadian period estimation. Overall, the average intrinsic period of the melatonin and temperature rhythms in this population was very close to 24 h [24.15 ± 0.2 h (24 h 9 min ± 12 min)]. We further found that the intrinsic circadian period was significantly shorter in women [24.09 ± 0.2 h (24 h 5 min ± 12 min)] than in men [24.19 ± 0.2 h (24 h 11 min ± 12 min); P < 0.01] and that a significantly greater proportion of women have intrinsic circadian periods shorter than 24.0 h (35% vs. 14%; P < 0.01). The shorter average intrinsic circadian period observed in women may have implications for understanding sex differences in habitual sleep duration and insomnia prevalence. PMID:21536890

  6. Global exponential periodicity and stability of discrete-time complex-valued recurrent neural networks with time-delays.

    PubMed

    Hu, Jin; Wang, Jun

    2015-06-01

    In recent years, complex-valued recurrent neural networks have been developed and analysed in-depth in view of that they have good modelling performance for some applications involving complex-valued elements. In implementing continuous-time dynamical systems for simulation or computational purposes, it is quite necessary to utilize a discrete-time model which is an analogue of the continuous-time system. In this paper, we analyse a discrete-time complex-valued recurrent neural network model and obtain the sufficient conditions on its global exponential periodicity and exponential stability. Simulation results of several numerical examples are delineated to illustrate the theoretical results and an application on associative memory is also given.

  7. A General Approach to Time Periodic Incompressible Viscous Fluid Flow Problems

    NASA Astrophysics Data System (ADS)

    Geissert, Matthias; Hieber, Matthias; Nguyen, Thieu Huy

    2016-06-01

    This article develops a general approach to time periodic incompressible fluid flow problems and semilinear evolution equations. It yields, on the one hand, a unified approach to various classical problems in incompressible fluid flow and, on the other hand, gives new results for periodic solutions to the Navier-Stokes-Oseen flow, the Navier-Stokes flow past rotating obstacles, and, in the geophysical setting, for Ornstein-Uhlenbeck and various diffusion equations with rough coefficients. The method is based on a combination of interpolation and topological arguments, as well as on the smoothing properties of the linearized equation.

  8. Continuous Time Random Walks in periodic systems: fluid limit and fractional differential equations on the circle

    SciTech Connect

    Calvo, Ivan; Carreras, Benjamin A; Sanchez, Raul; van Milligen, B. Ph.

    2007-01-01

    In this article, the continuous time random walk on the circle is studied. We derive the corresponding generalized master equation and discuss the effects of topology, especially important when Levy flights are allowed. Then, we work out the fluid limit equation, formulated in terms of the periodic version of the fractional Riemann-Liouville operators, for which we provide explicit expressions. Finally, we compute the propagator in some simple cases. The analysis presented herein should be relevant when investigating anomalous transport phenomena in systems with periodic dimensions.

  9. Plasticity of the Intrinsic Period of the Human Circadian Timing System

    PubMed Central

    Scheer, Frank A.J.L.; Wright, Kenneth P.; Kronauer, Richard E.; Czeisler, Charles A.

    2007-01-01

    Human expeditions to Mars will require adaptation to the 24.65-h Martian solar day-night cycle (sol), which is outside the range of entrainment of the human circadian pacemaker under lighting intensities to which astronauts are typically exposed. Failure to entrain the circadian time-keeping system to the desired rest-activity cycle disturbs sleep and impairs cognitive function. Furthermore, differences between the intrinsic circadian period and Earth's 24-h light-dark cycle underlie human circadian rhythm sleep disorders, such as advanced sleep phase disorder and non-24-hour sleep-wake disorders. Therefore, first, we tested whether exposure to a model-based lighting regimen would entrain the human circadian pacemaker at a normal phase angle to the 24.65-h Martian sol and to the 23.5-h day length often required of astronauts during short duration space exploration. Second, we tested here whether such prior entrainment to non-24-h light-dark cycles would lead to subsequent modification of the intrinsic period of the human circadian timing system. Here we show that exposure to moderately bright light (∼450 lux; ∼1.2 W/m2) for the second or first half of the scheduled wake episode is effective for entraining individuals to the 24.65-h Martian sol and a 23.5-h day length, respectively. Estimations of the circadian periods of plasma melatonin, plasma cortisol, and core body temperature rhythms collected under forced desynchrony protocols revealed that the intrinsic circadian period of the human circadian pacemaker was significantly longer following entrainment to the Martian sol as compared to following entrainment to the 23.5-h day. The latter finding of after-effects of entrainment reveals for the first time plasticity of the period of the human circadian timing system. Both findings have important implications for the treatment of circadian rhythm sleep disorders and human space exploration. PMID:17684566

  10. Magnus' expansion for time-periodic systems: Parameter-dependent approximations

    NASA Astrophysics Data System (ADS)

    Butcher, Eric A.; Sari, Ma'en; Bueler, Ed; Carlson, Tim

    2009-12-01

    Magnus' expansion solves the nonlinear Hausdorff equation associated with a linear time-varying system of ordinary differential equations by forming the matrix exponential of a series of integrated commutators of the matrix-valued coefficient. Instead of expanding the fundamental solution itself, that is, the logarithm is expanded. Within some finite interval in the time variable, such an expansion converges faster than direct methods like Picard iteration and it preserves symmetries of the ODE system, if present. For time-periodic systems, Magnus expansion, in some cases, allows one to symbolically approximate the logarithm of the Floquet transition matrix (monodromy matrix) in terms of parameters. Although it has been successfully used as a numerical tool, this use of the Magnus expansion is new. Here we use a version of Magnus' expansion due to Iserles [Iserles A. Expansions that grow on trees. Not Am Math Soc 2002;49:430-40], who reordered the terms of Magnus' expansion for more efficient computation. Though much about the convergence of the Magnus expansion is not known, we explore the convergence of the expansion and apply known convergence estimates. We discuss the possible benefits to using it for time-periodic systems, and we demonstrate the expansion on several examples of periodic systems through the use of a computer algebra system, showing how the convergence depends on parameters.

  11. Stability and attractivity of periodic solutions of parabolic systems with time delays

    NASA Astrophysics Data System (ADS)

    Pao, C. V.

    2005-04-01

    This paper is concerned with the existence, stability, and global attractivity of time-periodic solutions for a class of coupled parabolic equations in a bounded domain. The problem under consideration includes coupled system of parabolic and ordinary differential equations, and time delays may appear in the nonlinear reaction functions. Our approach to the problem is by the method of upper and lower solutions and its associated monotone iterations. The existence of time-periodic solutions is for a class of locally Lipschitz continuous reaction functions without any quasimonotone requirement using Schauder fixed point theorem, while the stability and attractivity analysis is for quasimonotone nondecreasing and mixed quasimonotone reaction functions using the monotone iterative scheme. The results for the general system are applied to the standard parabolic equations without time delay and to the corresponding ordinary differential system. Applications are also given to three Lotka-Volterra reaction diffusion model problems, and in each problem a sufficient condition on the reaction rates is obtained to ensure the stability and global attractivity of positive periodic solutions.

  12. Primate enamel evinces long period biological timing and regulation of life history.

    PubMed

    Bromage, Timothy G; Hogg, Russell T; Lacruz, Rodrigo S; Hou, Chen

    2012-07-21

    The factor(s) regulating the combination of traits that define the overall life history matrix of mammalian species, comprising attributes such as brain and body weight, age at sexual maturity, lifespan and others, remains a complete mystery. The principal objectives of the present research are (1) to provide evidence for a key variable effecting life history integration and (2) to provide a model for how one would go about investigating the metabolic mechanisms responsible for this rhythm. We suggest here that a biological rhythm with a period greater than the circadian rhythm is responsible for observed variation in primate life history. Evidence for this rhythm derives from studies of tooth enamel formation. Enamel contains an enigmatic periodicity in its microstructure called the striae of Retzius, which develops at species specific intervals in units of whole days. We refer to this enamel rhythm as the repeat interval (RI). For primates, we identify statistically significant relationships between RI and all common life history traits. Importantly, RI also correlates with basal and specific metabolic rates. With the exception of estrous cyclicity, all relationships share a dependence upon body mass. This dependence on body mass informs us that some aspect of metabolism is responsible for periodic energy allocations at RI timescales, regulating cell proliferation rates and growth, thus controlling the pace, patterning, and co-variation of life history traits. Estrous cyclicity relates to the long period rhythm in a body mass-independent manner. The mass-dependency and -independency of life history relationships with RI periodicity align with hypothalamic-mediated neurosecretory anterior and posterior pituitary outputs. We term this period the Havers-Halberg Oscillation (HHO), in reference to Clopton Havers, a 17th Century hard tissue anatomist, and Franz Halberg, a long-time explorer of long-period rhythms. We propose a mathematical model that may help elucidate

  13. Tracing temperature in a nanometer size region in a picosecond time period

    PubMed Central

    Nakajima, Kaoru; Kitayama, Takumi; Hayashi, Hiroaki; Matsuda, Makoto; Sataka, Masao; Tsujimoto, Masahiko; Toulemonde, Marcel; Bouffard, Serge; Kimura, Kenji

    2015-01-01

    Irradiation of materials with either swift heavy ions or slow highly charged ions leads to ultrafast heating on a timescale of several picosecond in a region of several nanometer. This ultrafast local heating result in formation of nanostructures, which provide a number of potential applications in nanotechnologies. These nanostructures are believed to be formed when the local temperature rises beyond the melting or boiling point of the material. Conventional techniques, however, are not applicable to measure temperature in such a localized region in a short time period. Here, we propose a novel method for tracing temperature in a nanometer region in a picosecond time period by utilizing desorption of gold nanoparticles around the ion impact position. The feasibility is examined by comparing with the temperature evolution predicted by a theoretical model. PMID:26293488

  14. Tracing temperature in a nanometer size region in a picosecond time period.

    PubMed

    Nakajima, Kaoru; Kitayama, Takumi; Hayashi, Hiroaki; Matsuda, Makoto; Sataka, Masao; Tsujimoto, Masahiko; Toulemonde, Marcel; Bouffard, Serge; Kimura, Kenji

    2015-08-21

    Irradiation of materials with either swift heavy ions or slow highly charged ions leads to ultrafast heating on a timescale of several picosecond in a region of several nanometer. This ultrafast local heating result in formation of nanostructures, which provide a number of potential applications in nanotechnologies. These nanostructures are believed to be formed when the local temperature rises beyond the melting or boiling point of the material. Conventional techniques, however, are not applicable to measure temperature in such a localized region in a short time period. Here, we propose a novel method for tracing temperature in a nanometer region in a picosecond time period by utilizing desorption of gold nanoparticles around the ion impact position. The feasibility is examined by comparing with the temperature evolution predicted by a theoretical model.

  15. Tracing temperature in a nanometer size region in a picosecond time period

    NASA Astrophysics Data System (ADS)

    Nakajima, Kaoru; Kitayama, Takumi; Hayashi, Hiroaki; Matsuda, Makoto; Sataka, Masao; Tsujimoto, Masahiko; Toulemonde, Marcel; Bouffard, Serge; Kimura, Kenji

    2015-08-01

    Irradiation of materials with either swift heavy ions or slow highly charged ions leads to ultrafast heating on a timescale of several picosecond in a region of several nanometer. This ultrafast local heating result in formation of nanostructures, which provide a number of potential applications in nanotechnologies. These nanostructures are believed to be formed when the local temperature rises beyond the melting or boiling point of the material. Conventional techniques, however, are not applicable to measure temperature in such a localized region in a short time period. Here, we propose a novel method for tracing temperature in a nanometer region in a picosecond time period by utilizing desorption of gold nanoparticles around the ion impact position. The feasibility is examined by comparing with the temperature evolution predicted by a theoretical model.

  16. Tracing temperature in a nanometer size region in a picosecond time period.

    PubMed

    Nakajima, Kaoru; Kitayama, Takumi; Hayashi, Hiroaki; Matsuda, Makoto; Sataka, Masao; Tsujimoto, Masahiko; Toulemonde, Marcel; Bouffard, Serge; Kimura, Kenji

    2015-01-01

    Irradiation of materials with either swift heavy ions or slow highly charged ions leads to ultrafast heating on a timescale of several picosecond in a region of several nanometer. This ultrafast local heating result in formation of nanostructures, which provide a number of potential applications in nanotechnologies. These nanostructures are believed to be formed when the local temperature rises beyond the melting or boiling point of the material. Conventional techniques, however, are not applicable to measure temperature in such a localized region in a short time period. Here, we propose a novel method for tracing temperature in a nanometer region in a picosecond time period by utilizing desorption of gold nanoparticles around the ion impact position. The feasibility is examined by comparing with the temperature evolution predicted by a theoretical model. PMID:26293488

  17. Periodic solutions of a nonautonomous predator-prey system with stage structure and time delays

    NASA Astrophysics Data System (ADS)

    Xu, Rui; Wang, Zhiqiang

    2006-11-01

    A nonautonomous Lotka-Volterra type predator-prey model with stage structure and time delays is investigated. It is assumed in the model that the individuals in each species may belong to one of two classes: the immatures and the matures, the age to maturity is presented by a time delay, and that the immature predators do not feed on prey and do not have the ability to reproduce. By some comparison arguments we first discuss the permanence of the model. By using the continuation theorem of coincidence degree theory, sufficient conditions are derived for the existence of positive periodic solutions to the model. By means of a suitable Lyapunov functional, sufficient conditions are obtained for the uniqueness and global stability of the positive periodic solutions to the model.

  18. Time functions of deep earthquakes from broadband and short-period stacks

    USGS Publications Warehouse

    Houston, H.; Benz, H.M.; Vidale, J.E.

    1998-01-01

    To constrain dynamic source properties of deep earthquakes, we have systematically constructed broadband time functions of deep earthquakes by stacking and scaling teleseismic P waves from U.S. National Seismic Network, TERRAscope, and Berkeley Digital Seismic Network broadband stations. We examined 42 earthquakes with depths from 100 to 660 km that occurred between July 1, 1992 and July 31, 1995. To directly compare time functions, or to group them by size, depth, or region, it is essential to scale them to remove the effect of moment, which varies by more than 3 orders of magnitude for these events. For each event we also computed short-period stacks of P waves recorded by west coast regional arrays. The comparison of broadband with short-period stacks yields a considerable advantage, enabling more reliable measurement of event duration. A more accurate estimate of the duration better constrains the scaling procedure to remove the effect of moment, producing scaled time functions with both correct timing and amplitude. We find only subtle differences in the broadband time-function shape with moment, indicating successful scaling and minimal effects of attenuation at the periods considered here. The average shape of the envelopes of the short-period stacks is very similar to the average broadband time function. The main variations seen with depth are (1) a mild decrease in duration with increasing depth, (2) greater asymmetry in the time functions of intermediate events compared to deep ones, and (3) unexpected complexity and late moment release for events between 350 and 550 km, with seven of the eight events in that depth interval displaying markedly more complicated time functions with more moment release late in the rupture than most events above or below. The first two results are broadly consistent with our previous studies, while the third is reported here for the first time. The greater complexity between 350 and 550 km suggests greater heterogeneity in

  19. Periodic Time-Domain Nonlocal Nonreflecting Boundary Conditions for Duct Acoustics

    NASA Technical Reports Server (NTRS)

    Watson, Willie R.; Zorumski, William E.

    1996-01-01

    Periodic time-domain boundary conditions are formulated for direct numerical simulation of acoustic waves in ducts without flow. Well-developed frequency-domain boundary conditions are transformed into the time domain. The formulation is presented here in one space dimension and time; however, this formulation has an advantage in that its extension to variable-area, higher dimensional, and acoustically treated ducts is rigorous and straightforward. The boundary condition simulates a nonreflecting wave field in an infinite uniform duct and is implemented by impulse-response operators that are applied at the boundary of the computational domain. These operators are generated by convolution integrals of the corresponding frequency-domain operators. The acoustic solution is obtained by advancing the Euler equations to a periodic state with the MacCormack scheme. The MacCormack scheme utilizes the boundary condition to limit the computational space and preserve the radiation boundary condition. The success of the boundary condition is attributed to the fact that it is nonreflecting to periodic acoustic waves. In addition, transient waves can pass rapidly out of the solution domain. The boundary condition is tested for a pure tone and a multitone source in a linear setting. The effects of various initial conditions are assessed. Computational solutions with the boundary condition are consistent with the known solutions for nonreflecting wave fields in an infinite uniform duct.

  20. Time-varying singular value decomposition for periodic transient identification in bearing fault diagnosis

    NASA Astrophysics Data System (ADS)

    Zhang, Shangbin; Lu, Siliang; He, Qingbo; Kong, Fanrang

    2016-09-01

    For rotating machines, the defective faults of bearings generally are represented as periodic transient impulses in acquired signals. The extraction of transient features from signals has been a key issue for fault diagnosis. However, the background noise reduces identification performance of periodic faults in practice. This paper proposes a time-varying singular value decomposition (TSVD) method to enhance the identification of periodic faults. The proposed method is inspired by the sliding window method. By applying singular value decomposition (SVD) to the signal under a sliding window, we can obtain a time-varying singular value matrix (TSVM). Each column in the TSVM is occupied by the singular values of the corresponding sliding window, and each row represents the intrinsic structure of the raw signal, namely time-singular-value-sequence (TSVS). Theoretical and experimental analyses show that the frequency of TSVS is exactly twice that of the corresponding intrinsic structure. Moreover, the signal-to-noise ratio (SNR) of TSVS is improved significantly in comparison with the raw signal. The proposed method takes advantages of the TSVS in noise suppression and feature extraction to enhance fault frequency for diagnosis. The effectiveness of the TSVD is verified by means of simulation studies and applications to diagnosis of bearing faults. Results indicate that the proposed method is superior to traditional methods for bearing fault diagnosis.

  1. Rank One Chaos in Periodically-Kicked Time-Delayed Chen System

    NASA Astrophysics Data System (ADS)

    Dai, Yunxian; Lin, Yiping; Yang, Wenjie; Zhao, Huitao

    In this paper, we study the existence of rank one strange attractor in time-delayed system. First, we try to develop rank one theory for delayed differential equations. Then, we consider Chen system with time-delay, the conditions under which a supercritical Hopf bifurcation occurs are given by using the normal form method and center manifold theorem. Then, we add an external periodic force as an input and observe rank one strange attractors. Finally, several numerical simulations supporting the theoretical analysis are also given.

  2. Real-time Periodic Processing of RT-middleware Utilizing Linux Standard Functionalities

    NASA Astrophysics Data System (ADS)

    Shimizu, Masaharu; Toda, Kengo; Hayashibara, Yasuo; Yamato, Hideaki; Furuta, Takayuki

    A new methodology of real-time periodic processing on RT-middleware based on the Linux standard functionalities is presented in this paper. The central of discussion is on the realization of real-time processing while keeping the reusability of software modules ensured by the RT-middleware framework as well as the portability provided by the Linux development mainstream. In order to show the validity of the proposed approach, two robot systems, including an omnidirectional electric wheelchair steered by haptic joystick, are presented and the discussion about the evaluation result follows from the view point of practicality.

  3. Quasiequilibrium directed hopping in a time-dependent two-well periodic potential

    NASA Astrophysics Data System (ADS)

    Rozenbaum, V. M.; Shapochkina, I. V.

    2011-11-01

    We consider the directed motion of a Brownian particle in a two-well periodic potential with time-varying barriers and wells described by arbitrary periodic functions of time, v(t) and u(t), alternating with the period τ. In the framework of the low-temperature kinetic approach, we obtain explicit formulas for the probabilities of finding the particle in potential wells, average velocity of directed motion, input energy Pin and useful work Pout against additionally introduced stationary load force f. These formulas are considerably simplified by the assumption of the quasiequilibrium regime of motion corresponding to small values of u(t) and f. It is shown that depending on the same or opposite parity of the functions v(t) and u(t) with respect to time reversal, the motion direction of a Brownian particle is retained or reversed under the reversal of the direction of movement along the (v-u) loop in the phase space of the functions v(t) and u(t), and the nondiagonal kinetic coefficients are mutually symmetric or antisymmetric. In the adiabatic limit τ→∞, the average velocity is proportional to τ-1 in two cases: (i) the above loop has a nonzero area, (ii) the functions v(t) and u(t) are proportional to each other (zero loop area) and include intervals of fast changes with small durations τ0 on the period τ of their variations. In both of these cases, the efficiency of energy conversion, η=Pout/Pin, tends to unity at large variations of the barriers v(t). In the second case, the deviation of η from unity can be split into two contributions: The former decreases exponentially with increasing amplitude v0 of v(t), while the latter is a small nonadiabatic correction proportional to v0-3/2. It is the nonadiabatic correction that limits high efficiencies at large variations of barriers.

  4. Timing Studies of X Persei and the Discovery of Its Transient Quasi-periodic Oscillation Feature

    NASA Technical Reports Server (NTRS)

    Acuner, Z.; Inam,S. C.; Sahiner, S.; Serim, M. M.; Baykal, A.; Swank, J.

    2014-01-01

    We present a timing analysis of X Persei (X Per) using observations made between 1998 and 2010 with the Proportional Counter Array (PCA) onboard the Rossi X-ray Timing Explorer (RXTE) and with the INTEGRAL Soft Gamma-Ray Imager (ISGRI). All pulse arrival times obtained from the RXTE-PCA observations are phase-connected and a timing solution is obtained using these arrival times. We update the long-term pulse frequency history of the source by measuring its pulse frequencies using RXTE-PCA and ISGRI data. From the RXTEPCA data, the relation between the frequency derivative and X-ray flux suggests accretion via the companion's stellar wind. However, the detection of a transient quasi-periodic oscillation feature, peaking at approximately 0.2 Hz, suggests the existence of an accretion disc. We find that doublebreak models fit the average power spectra well, which suggests that the source has at least two different accretion flow components dominating the overall flow. From the power spectrum of frequency derivatives, we measure a power-law index of approximately - 1, which implies that, on short time-scales, disc accretion dominates over noise, while on time-scales longer than the viscous time-scales, the noise dominates. From pulse profiles, we find a correlation between the pulse fraction and the count rate of the source.

  5. Detection of faults in rotating machinery using periodic time-frequency sparsity

    NASA Astrophysics Data System (ADS)

    Ding, Yin; He, Wangpeng; Chen, Binqiang; Zi, Yanyang; Selesnick, Ivan W.

    2016-11-01

    This paper addresses the problem of extracting periodic oscillatory features in vibration signals for detecting faults in rotating machinery. To extract the feature, we propose an approach in the short-time Fourier transform (STFT) domain where the periodic oscillatory feature manifests itself as a relatively sparse grid. To estimate the sparse grid, we formulate an optimization problem using customized binary weights in the regularizer, where the weights are formulated to promote periodicity. In order to solve the proposed optimization problem, we develop an algorithm called augmented Lagrangian majorization-minimization algorithm, which combines the split augmented Lagrangian shrinkage algorithm (SALSA) with majorization-minimization (MM), and is guaranteed to converge for both convex and non-convex formulation. As examples, the proposed approach is applied to simulated data, and used as a tool for diagnosing faults in bearings and gearboxes for real data, and compared to some state-of-the-art methods. The results show that the proposed approach can effectively detect and extract the periodical oscillatory features.

  6. Transfer-matrix approach for finite-difference time-domain simulation of periodic structures.

    PubMed

    Deinega, Alexei; Belousov, Sergei; Valuev, Ilya

    2013-11-01

    Optical properties of periodic structures can be calculated using the transfer-matrix approach, which establishes a relation between amplitudes of the wave incident on a structure with transmitted or reflected waves. The transfer matrix can be used to obtain transmittance and reflectance spectra of finite periodic structures as well as eigenmodes of infinite structures. Traditionally, calculation of the transfer matrix is performed in the frequency domain and involves linear algebra. In this work, we present a technique for calculation of the transfer matrix using the finite-difference time-domain (FDTD) method and show the way of its implementation in FDTD code. To illustrate the performance of our technique we calculate the transmittance spectra for opal photonic crystal slabs consisting of multiple layers of spherical scatterers. Our technique can be used for photonic band structure calculations. It can also be combined with existing FDTD methods for the analysis of periodic structures at an oblique incidence, as well as for modeling point sources in a periodic environment. PMID:24329377

  7. Resonating Vector Strength: How to Find Periodicity in a Time Sequence

    NASA Astrophysics Data System (ADS)

    van Hemmen, J. Leo

    2013-03-01

    For a given periodic stimulus with angular frequency ω∘ = 2 π /T∘ we find responses as events at times {t1 ,t2 , ... ,tn } located on the real axis R. How periodic are they? And do they repeat in ``some'' sense in accordance with the stimulus period T∘? The question and the answer are at least as old as a classical paper of von Mises dating back to 1918. The key idea is simply this. We map the events tj onto the unit circle or torus through tj |-> exp (iωtj) and consider their center of gravity, ρ (ω) , a complex number in the unit disk. Its absolute value | ρ (ω∘) | with ω : =ω∘ is what von Mises studied and is now called the vector strength. We prove that the nearer | ρ (ω∘) | is to 1 the more periodic the events tj are w.r.t. T∘. Furthermore, we also show why it is useful to study ρ (ω) as a function of ω so as to obtain a `resonating' vector strength, an idea strongly deviating from the classical characteristic function. Work done in collaboration with A.N. Vollmayr. Partially supported by BCCN-Munich.

  8. Unstable and exact periodic solutions of three-particles time-dependent FPU chains

    NASA Astrophysics Data System (ADS)

    Liu, Qi-Huai; Xing, Ming-Yan; Li, Xin-Xiang; Wang, Chao

    2015-12-01

    For lower dimensional Fermi-Pasta-Ulam (FPU) chains, the α-chain is completely integrable and the Hamiltonian of the β-chain can be identified with the Hénon-Heiles Hamiltonian. When the strengths α, β of the nonlinearities depend on time periodically with the same frequencies as the natural angular frequencies, the resonance phenomenon is inevitable. In this paper, for certain periodic functions α(t) and β(t) with resonance frequencies, we give the existence and stability of some nontrivial exact periodic solutions for a one-dimensional αβ-FPU model composed of three particles with periodic boundary conditions. Project supported by the National Natural Science Foundation of China (Grant Nos. 11301106, 11201288, and 11261013), the Natural Science Foundation of Guangxi Zhuang Autonomous Region, China (Grant No. 2014GXNSFBA118017), the Innovation Project of Graduate Education of Guangxi Zhuang Autonomous Region, China, (Grant No. YCSZ2014143), and the Guangxi Experiment Center of Information Science (Grant No. YB1410).

  9. Transfer-matrix approach for finite-difference time-domain simulation of periodic structures.

    PubMed

    Deinega, Alexei; Belousov, Sergei; Valuev, Ilya

    2013-11-01

    Optical properties of periodic structures can be calculated using the transfer-matrix approach, which establishes a relation between amplitudes of the wave incident on a structure with transmitted or reflected waves. The transfer matrix can be used to obtain transmittance and reflectance spectra of finite periodic structures as well as eigenmodes of infinite structures. Traditionally, calculation of the transfer matrix is performed in the frequency domain and involves linear algebra. In this work, we present a technique for calculation of the transfer matrix using the finite-difference time-domain (FDTD) method and show the way of its implementation in FDTD code. To illustrate the performance of our technique we calculate the transmittance spectra for opal photonic crystal slabs consisting of multiple layers of spherical scatterers. Our technique can be used for photonic band structure calculations. It can also be combined with existing FDTD methods for the analysis of periodic structures at an oblique incidence, as well as for modeling point sources in a periodic environment.

  10. Practitioners' Perceptions of the Soccer Extra-Time Period: Implications for Future Research

    PubMed Central

    Harper, Liam D.; Fothergill, Melissa; West, Daniel J.; Stevenson, Emma; Russell, Mark

    2016-01-01

    Qualitative research investigating soccer practitioners’ perceptions can allow researchers to create practical research investigations. The extra-time period of soccer is understudied compared to other areas of soccer research. Using an open-ended online survey containing eleven main and nine sub questions, we gathered the perceptions of extra-time from 46 soccer practitioners, all working for different professional soccer clubs. Questions related to current practices, views on extra-time regulations, and ideas for future research. Using inductive content analysis, the following general dimensions were identified: ‘importance of extra-time’, ‘rule changes’, ‘efficacy of extra-time hydro-nutritional provision’, ‘nutritional timing’, ‘future research directions’, ‘preparatory modulations’ and ‘recovery’. The majority of practitioners (63%) either agreed or strongly agreed that extra-time is an important period for determining success in knockout football match-play. When asked if a fourth substitution should be permitted in extra-time, 67% agreed. The use of hydro-nutritional strategies prior to extra-time was predominately considered important or very important. However; only 41% of practitioners felt that it was the most important time point for the use of nutritional products. A similar number of practitioners account (50%) and do not (50%) account for the potential of extra-time when training and preparing players and 89% of practitioners stated that extra-time influences recovery practices following matches. In the five minute break prior to extra-time, the following practices (in order of priority) were advocated to players: hydration, energy provision, massage, and tactical preparations. Additionally, 87% of practitioners advocate a particular nutritional supplementation strategy prior to extra-time. In order of importance, practitioners see the following as future research areas: nutritional interventions, fatigue responses

  11. Comparison of antimicrobial susceptibility of Citrobacter freundii isolates in two different time periods.

    PubMed

    Wang, J T; Chang, S C; Chen, Y C; Luh, K T

    2000-12-01

    Citrobacter freundii was first identified in 1932, since then it has been reported to cause a variety of infections in aged, immunocompromised, and debilitated patients. With the use of broad-spectrum antibiotics, C. freundii has become increasingly resistant to antimicrobial agents. In order to determine the chronological changes in susceptibility and current susceptibility status of C. freundii, we compared the antimicrobial susceptibility of C. freundii in two different time periods, from 1987 to 1988 and from 1997 to 1998. In both time periods, 61 isolates of C. freundii were randomly selected for study from all clinical isolates at National Taiwan University Hospital. The minimum inhibitory concentrations and susceptible rates of 15 antimicrobial agents were compared, and it was found that most C. freundii isolates were resistant to anti-pseudomonal penicillins, first, second, and third generation cephalosporins, gentamicin, tobramycin, and aztreonam. The results indicate that the susceptible rates of C. freundii to aminoglycosides and ciprofloxacin decreased markedly during the period from 1987 to 1998. Cefepime, cefpirome, imipenem, and meropenem remained the most active agents against C. freundii.

  12. Reaction time-related activity reflecting periodic, task-specific cognitive control.

    PubMed

    Barber, Anita D; Pekar, James J; Mostofsky, Stewart H

    2016-01-01

    Reaction time (RT) is associated with increased amplitude of the Blood Oxygen-Level Dependent (BOLD) response in cognitive control regions. The current study examined whether the Primary Condition (PC) effect and RT-BOLD effect both reflect the same cognitive control processes. In addition, RT-BOLD effects were examined in two Go/No-go tasks with different demands to determine whether RT-related activity is task-dependent, reflecting the recruitment of task-specific cognitive processes. Data simulations showed that RT-related activity could be distinguished from that of the primary condition if it is mean-centered. In that case, RT-related activity reflects periodically-engaged processes rather than "time-on-task" (ToT). RT-related activity was mostly distinct from that of the primary Go contrast, particularly for the perceptual decision task. Therefore, RT effects can reflect additional cognitive processes that are not captured by the PC contrast consistent with a periodic-engagement account. RT-BOLD effects occurred in a separate set of regions for the two tasks. For the task requiring a perceptual decision, RT-related activity occurred within occipital and posterior parietal regions supporting visual attention. For the task requiring a working memory decision, RT-related activity occurred within fronto-parietal regions supporting the maintenance and retrieval of task representations. The findings suggest that RT-related activity reflects task-specific processes that are periodically-engaged, particularly during less demanding tasks. PMID:26318935

  13. Periodical gait asymmetry assessment using real-time wireless gyroscopes gait monitoring system.

    PubMed

    Gouwanda, D; Senanayake, S M N A

    2011-11-01

    A real-time gait monitoring system that incorporates an immediate and periodical assessment of gait asymmetry is described. This system was designed for gait analysis and rehabilitation of patients with pathologic gait. It employs wireless gyroscopes to measure the angular rate of the thigh and shank in real time. Cross-correlation of the lower extremity (Cc(norm)), and normalized Symmetry Index (SI(norm)) are implemented as new approaches to periodically determine the gait asymmetry in each gait cycle. Cc(norm) evaluates the signal patterns measured by wireless gyroscopes in each gait cycle. SI(norm) determines the movement differences between the left and right limb. An experimental study was conducted to examine the viability of these methods. Artificial asymmetrical gait was simulated by placing a load on one side of the limbs. Results showed that there were significant differences between the normal gait and asymmetrical gait (p < 0.01). They also indicated that the system worked well in periodically assessing the gait asymmetry.

  14. Estimation of the Unextendable Dead Time Period in a Flow of Physical Events by the Method of Maximum Likelihood

    NASA Astrophysics Data System (ADS)

    Nezhel'skaya, L. A.

    2016-09-01

    A flow of physical events (photons, electrons, and other elementary particles) is studied. One of the mathematical models of such flows is the modulated MAP flow of events circulating under conditions of unextendable dead time period. It is assumed that the dead time period is an unknown fixed value. The problem of estimation of the dead time period from observations of arrival times of events is solved by the method of maximum likelihood.

  15. Performance of ROB's near real-time ionospheric product during normal and disturbed space weather periods.

    NASA Astrophysics Data System (ADS)

    Bergeot, Nicolas; Chevalier, Jean-Marie; Bruyninx, Carine

    2015-04-01

    Several agencies are routinely monitoring the vertical Total Electron Content (vTEC) using GNSS data. Derived maps are available with different latencies, area extents, and grid/time resolutions. However, no high-resolution maps are publically available over Europe in near real-time. In this frame, the Royal Observatory of Belgium (ROB) developed the ROB-IONO software which takes advantage of the dense EUREF Permanent GNSS Network (EPN) to monitor the ionosphere. The main ROB products consist of ionospheric vTEC maps over Europe and their variability estimated in near real-time every 15 min on 0.5° x 0.5° grids using GPS observations. The maps are available online with a latency of ~3 min in the IONEX format at ftp://gnss.oma.be and as interactive web pages at www.gnss.be. During normal ionospheric activity, the ROB-TEC maps show a good agreement with widely used post-processed global products from IGS, CODE and ESA, with mean differences of 1.3 ± 0.9, 0.6 ± 0.7 and 0.4 ± 1.6 TECu respectively for the period 2012 to mid-2013. For a disturbed period, such as the 2003 Halloween ionospheric storm, the mean differences with IGS, CODE and ESA maps are respectively 0.9 ± 2.2, 0.1 ± 2.0 and 0.6 ± 6.8 TECu, with maximum differences (>38 TECu) occurring during the major phase of the storm. These differences are due to the lower resolution of global products in time and space compared to the ROB-TEC maps. A description of two recent events, on March 17, 2013 and February 27, 2014 highlights the capability of the method adopted to detect in near real-time abnormal ionospheric behaviour over Europe. The potential of the variability maps as an indicator of rapid ionospheric variations during the 15 min of observations is also highlighted. More than 30 ionospheric events associated with Space weather were detected during the period 2012-2014. The ionospheric perturbations are associated with Coronal Mass Ejections (CMEs, ~70% of the time), active geomagnetic conditions

  16. Time-periodic forcing of Turing patterns in the Brusselator model

    NASA Astrophysics Data System (ADS)

    Peña, B.; Pérez-García, C.

    Experiments on periodic illumination of the CDIMA (chlorine dioxide-iodine-malonic acid) reaction have revealed that Turing patterns can be supressed for sufficiently high intensities [1]. The illumination modifies linearly the chemical kinetics. Here we present a preliminar work on Turing patterns under a time-periodic forcing of the control parameter in the Brusselator model. We have performed numerical simulations of the model under conditions for which reentrant hexagons appear. Surprisingly, the oscillating pattern can change its symmetry for a high enough amplitude forcing: a hexagonal pattern is replaced by oscillating squares, a kind of pattern still unobserved in chemical experiments. The theoretical mechanism underlying this change of symmetry is still under discussion.

  17. Practical time-delay synchronization of a periodically modulated self-excited oscillators with uncertainties.

    PubMed

    Kakmeni, F M Moukam; Bowong, S; Senthikumar, D V; Kurths, J

    2010-12-01

    This paper studies time-delay synchronization of a periodically modulated Duffing Van der Pol (DVP) oscillator subjected to uncertainties with emphasis on complete synchronization. A robust adaptive response system is designed to synchronize with the uncertain drive periodically modulated DVP oscillator. Adaptation laws on the upper bounds of uncertainties are proposed to guarantee the boundedness of both the synchronization error and the estimated feedback coupling gains. Numerical results are presented to check the effectiveness of the proposed synchronization scheme. The results suggest that the linear and nonlinear terms in the feedback coupling play a complementary role in increasing the synchronization regime in the parameter space of the synchronization manifold. The proposed method can be successfully applied to a large variety of physical systems. PMID:21198091

  18. Time-headway distribution for periodic totally asymmetric exclusion process with various updates

    NASA Astrophysics Data System (ADS)

    Hrabák, P.; Krbálek, M.

    2016-03-01

    The totally asymmetric exclusion process (TASEP) with periodic boundaries is considered as traffic flow model. The large-L approximation of the stationary state is used for the derivation of the time-headway distribution (an important microscopic characteristic of traffic flow) for the model with generalized update (genTASEP) in both, forward- and backward-sequential representations. The usually used updates, fully-parallel and regular forward- and backward-sequential, are analyzed as special cases of the genTASEP. It is shown that only for those cases, the time-headway distribution is determined by the flow regardless to the density. The qualitative comparison of the results with traffic data demonstrates that the genTASEP with backward order and attractive interaction evinces similar properties of time-headway distribution as the real traffic sample.

  19. Ultrafast time dynamics studies of periodic lattices with free electron laser radiation

    SciTech Connect

    Quevedo, W.; Busse, G.; Hallmann, J.; More, R.; Petri, M.; Rajkovic, I.; Krasniqi, F.; Rudenko, A.; Tschentscher, T.; Stojanovic, N.; Duesterer, S.; Treusch, R.; Tolkiehn, M.; Techert, S.

    2012-11-01

    It has been proposed that radiation from free electron laser (FEL) at Hamburg (FLASH) can be used for ultrafast time-resolved x-ray diffraction experiments based on the near-infrared (NIR) pump/FEL probe scheme. Here, investigation probing the ultrafast structural dynamics of periodic nano-crystalline organic matter (silver behenate) with such a scheme is reported. Excitation with a femtosecond NIR laser leads to an ultrafast lattice modification which time evolution has been studied through the scattering of vacuum ultraviolet FEL pulses. The found effect last for 6 ps and underpins the possibility for studying nanoperiodic dynamics down to the FEL source time resolution. Furthermore, the possibility of extending the use of silver behenate (AgBh) as a wavelength and temporal calibration tool for experiments with soft x-ray/FEL sources is suggested.

  20. Evaluation of indoor air composition time variation in air-tight occupied spaces during night periods

    NASA Astrophysics Data System (ADS)

    Markov, Detelin

    2012-11-01

    This paper presents an easy-to-understand procedure for prediction of indoor air composition time variation in air-tight occupied spaces during the night periods. The mathematical model is based on the assumptions for homogeneity and perfect mixing of the indoor air, the ideal gas model for non-reacting gas mixtures, mass conservation equations for the entire system and for each species, a model for prediction of basal metabolic rate of humans as well as a model for prediction of O2 consumption rate and both CO2 and H2O generation rates by breathing. Time variation of indoor air composition is predicted at constant indoor air temperature for three scenarios based on the analytical solution of the mathematical model. The results achieved reveal both the most probable scenario for indoor air time variation in air-tight occupied spaces as well as the cause for morning tiredness after having a sleep in a modern energy efficient space.

  1. Time-Periodic Solutions of Driven-Damped Trimer Granular Crystals

    DOE PAGES

    Charalampidis, E. G.; Li, F.; Chong, C.; Yang, J.; Kevrekidis, P. G.

    2015-01-01

    We consider time-periodic structures of granular crystals consisting of alternate chrome steel (S) and tungsten carbide (W) spherical particles where each unit cell follows the pattern of a 2 : 1 trimer: S-W-S. The configuration at the left boundary is driven by a harmonic in-time actuation with given amplitude and frequency while the right one is a fixed wall. Similar to the case of a dimer chain, the combination of dissipation, driving of the boundary, and intrinsic nonlinearity leads to complex dynamics. For fixed driving frequencies in each of the spectral gaps, we find that the nonlinear surface modes and the statesmore » dictated by the linear drive collide in a saddle-node bifurcation as the driving amplitude is increased, beyond which the dynamics of the system becomes chaotic. While the bifurcation structure is similar for solutions within the first and second gap, those in the first gap appear to be less robust. We also conduct a continuation in driving frequency, where it is apparent that the nonlinearity of the system results in a complex bifurcation diagram, involving an intricate set of loops of branches, especially within the spectral gap. The theoretical findings are qualitatively corroborated by the experimental full-field visualization of the time-periodic structures.« less

  2. 32 CFR 552.80 - Suspension period.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Suspension period. 552.80 Section 552.80 National... Suspension period. All solicitation privileges suspended by installation commanders will be for a specific time. Normally, it will not exceed 2 years. When the suspension period expires, the agent may...

  3. 32 CFR 552.80 - Suspension period.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Suspension period. 552.80 Section 552.80 National... Suspension period. All solicitation privileges suspended by installation commanders will be for a specific time. Normally, it will not exceed 2 years. When the suspension period expires, the agent may...

  4. Hydromagnetic natural convection flow between vertical parallel plates with time-periodic boundary conditions

    NASA Astrophysics Data System (ADS)

    Adesanya, S. O.; Oluwadare, E. O.; Falade, J. A.; Makinde, O. D.

    2015-12-01

    In this paper, the free convective flow of magnetohydrodynamic fluid through a channel with time periodic boundary condition is investigated by taking the effects of Joule dissipation into consideration. Based on simplifying assumptions, the coupled governing equations are reduced to a set of nonlinear boundary valued problem. Approximate solutions are obtained by using semi-analytical Adomian decomposition method. The effect of pertinent parameters on the fluid velocity, temperature distribution, Nusselt number and skin friction are presented graphically and discussed. The result of the computation shows that an increase in the magnetic field intensity has significant influence on the fluid flow.

  5. Geometric tools for solving the FDI problem for linear periodic discrete-time systems

    NASA Astrophysics Data System (ADS)

    Longhi, Sauro; Monteriù, Andrea

    2013-07-01

    This paper studies the problem of detecting and isolating faults in linear periodic discrete-time systems. The aim is to design an observer-based residual generator where each residual is sensitive to one fault, whilst remaining insensitive to the other faults that can affect the system. Making use of the geometric tools, and in particular of the outer observable subspace notion, the Fault Detection and Isolation (FDI) problem is formulated and necessary and solvability conditions are given. An algorithmic procedure is described to determine the solution of the FDI problem.

  6. The Cluster Science Archive: from Time Period to Physics Based Search

    NASA Astrophysics Data System (ADS)

    Masson, A.; Escoubet, C. P.; Laakso, H. E.; Perry, C. H.

    2015-12-01

    Since 2000, the Cluster spacecraft relay the most detailed information on how the solar wind affects our geospace in three dimensions. Science output from Cluster is a leap forward in our knowledge of space plasma physics: the science behind space weather. It has been key in improving the modeling of the magnetosphere and understanding its various physical processes. Cluster data have enabled the publication of more than 2000 refereed papers and counting. This substantial scientific return is often attributed to the online availability of the Cluster data archive, now called the Cluster Science Archive (CSA). It is being developed by the ESAC Science Data Center (ESDC) team and maintained alongside other science ESA archives at ESAC (ESA Space Astronomy Center, Madrid, Spain). CSA is a public archive, which contains the entire set of Cluster high-resolution data, and other related products in a standard format and with a complete set of metadata. Since May 2015, it also contains data from the CNSA/ESA Double Star mission (2003-2008), a mission operated in conjunction with Cluster. The total amount of data format now exceeds 100 TB. Accessing CSA requires to be registered to enable user profiles and CSA accounts more than 1,500 users. CSA provides unique tools for visualizing its data including - on-demand particle distribution functions visualization - fast data browsing with more than 15TB of pre-generated plots - inventory plots It also offers command line capabilities (e.g. data access via Matlab or IDL softwares, data streaming). Despite its reliability, users can only request data for a specific time period while scientists often focus on specific regions or data signatures. For these reasons, a data-mining tool is being developed to do just that. It offers an interface to select data based not only on a time period but on various criteria including: key physical parameters, regions of space and spacecraft constellation geometry. The output of this tool is a

  7. Thermomagnetic convection in a ferrofluid layer exposed to a time-periodic magnetic field

    NASA Astrophysics Data System (ADS)

    Matura, P.; Lücke, M.

    2009-08-01

    We have investigated the influence of a time-periodic and spatially homogeneous magnetic field on the linear stability properties and on the nonlinear response of a ferrofluid layer heated from below and from above. A competition between stabilizing thermal and viscous diffusion and destabilizing buoyancy and Kelvin forces occurs. Floquet theory is used to determine the stability boundaries of the motionless conductive state for a harmonic and subharmonic response. Full numerical simulations with a finite difference method were made to obtain nonlinear convective states. The effect of low- and high-frequency modulation on the stability boundaries as well as on the nonlinear oscillations that may occur is investigated.

  8. Finite-time position and velocity estimation adapted to noisy biased acceleration measurements from periodic motion

    NASA Astrophysics Data System (ADS)

    Estrada, Antonio; Efimov, Denis; Perruquetti, Wilfrid

    2016-09-01

    The present work focuses on the problem of velocity and position estimation. A solution is presented for a class of oscillating systems in which position, velocity and acceleration are zero mean signals. The proposed scheme considers that the dynamic model of the system is unknown. Only noisy acceleration measurements, that may be contaminated by zero mean noise and constant bias, are considered to be available. The proposal uses the periodic nature of the signals obtaining finite-time estimations while tackling integration drift accumulation.

  9. Stability analysis of a time-periodic 2-dof MEMS structure

    NASA Astrophysics Data System (ADS)

    Kniffka, Till Jochen; Welte, Johannes; Ecker, Horst

    2012-11-01

    Microelectromechanical systems (MEMS) are becoming important for all kinds of industrial applications. Among them are filters in communication devices, due to the growing demand for efficient and accurate filtering of signals. In recent developments single degree of freedom (1-dof) oscillators, that are operated at a parametric resonances, are employed for such tasks. Typically vibration damping is low in such MEM systems. While parametric excitation (PE) is used so far to take advantage of a parametric resonance, this contribution suggests to also exploit parametric anti-resonances in order to improve the damping behavior of such systems. Modeling aspects of a 2-dof MEM system and first results of the analysis of the non-linear and the linearized system are the focus of this paper. In principle the investigated system is an oscillating mechanical system with two degrees of freedom x = [x1x2]T that can be described by Mx+Cx+K1x+K3(x2)x+Fes(x,V(t)) = 0. The system is inherently non-linear because of the cubic mechanical stiffness K3 of the structure, but also because of electrostatic forces (1+cos(ωt))Fes(x) that act on the system. Electrostatic forces are generated by comb drives and are proportional to the applied time-periodic voltage V(t). These drives also provide the means to introduce time-periodic coefficients, i.e. parametric excitation (1+cos(ωt)) with frequency ω. For a realistic MEM system the coefficients of the non-linear set of differential equations need to be scaled for efficient numerical treatment. The final mathematical model is a set of four non-linear time-periodic homogeneous differential equations of first order. Numerical results are obtained from two different methods. The linearized time-periodic (LTP) system is studied by calculating the Monodromy matrix of the system. The eigenvalues of this matrix decide on the stability of the LTP-system. To study the unabridged non-linear system, the bifurcation software ManLab is employed

  10. Time series modelling of increased soil temperature anomalies during long period

    NASA Astrophysics Data System (ADS)

    Shirvani, Amin; Moradi, Farzad; Moosavi, Ali Akbar

    2015-10-01

    Soil temperature just beneath the soil surface is highly dynamic and has a direct impact on plant seed germination and is probably the most distinct and recognisable factor governing emergence. Autoregressive integrated moving average as a stochastic model was developed to predict the weekly soil temperature anomalies at 10 cm depth, one of the most important soil parameters. The weekly soil temperature anomalies for the periods of January1986-December 2011 and January 2012-December 2013 were taken into consideration to construct and test autoregressive integrated moving average models. The proposed model autoregressive integrated moving average (2,1,1) had a minimum value of Akaike information criterion and its estimated coefficients were different from zero at 5% significance level. The prediction of the weekly soil temperature anomalies during the test period using this proposed model indicated a high correlation coefficient between the observed and predicted data - that was 0.99 for lead time 1 week. Linear trend analysis indicated that the soil temperature anomalies warmed up significantly by 1.8°C during the period of 1986-2011.

  11. Evolution of illustrations in anatomy: a study from the classical period in Europe to modern times.

    PubMed

    Ghosh, Sanjib Kumar

    2015-01-01

    Illustrations constitute an essential element of learning anatomy in modern times. However it required a significant evolutionary process spread over centuries, for illustrations to achieve the present status in the subject of anatomy. This review article attempts to outline the evolutionary process by highlighting on the works of esteemed anatomists in a chronological manner. Available literature suggests that illustrations were not used in anatomy during the classical period when the subject was dominated by the descriptive text of Galen. Guido da Vigevano was first to use illustrations in anatomy during the Late Middle Ages and this concept developed further during the Renaissance period when Andreas Vesalius pioneered in illustrations becoming an indispensable tool in conveying anatomical details. Toward later stages of the Renaissance period, Fabricius ab Aquapendente endeavored to restrict dramatization of anatomical illustrations which was a prevalent trend in early Renaissance. During the 18th century, anatomical artwork was characterized by the individual styles of prominent anatomists leading to suppression of anatomical details. In the 19th century, Henry Gray used illustrations in his anatomical masterpiece that focused on depicting anatomical structures and were free from any artistic style. From early part of the 20th century medical images and photographs started to complement traditional handmade anatomical illustrations. Computer technology and advanced software systems played a key role in the evolution of anatomical illustrations during the late 20th century resulting in new generation 3D image datasets that are being used in the 21st century in innovative formats for teaching and learning anatomy.

  12. Periodic boundary conditions for long-time nonequilibrium molecular dynamics simulations of incompressible flows

    NASA Astrophysics Data System (ADS)

    Dobson, Matthew

    2014-11-01

    This work presents a generalization of the Kraynik-Reinelt (KR) boundary conditions for nonequilibrium molecular dynamics simulations. In the simulation of steady, homogeneous flows with periodic boundary conditions, the simulation box deforms with the flow, and it is possible for image particles to become arbitrarily close, causing a breakdown in the simulation. The KR boundary conditions avoid this problem for planar elongational flow and general planar mixed flow [T. A. Hunt, S. Bernardi, and B. D. Todd, J. Chem. Phys. 133, 154116 (2010)] through careful choice of the initial simulation box and by periodically remapping the simulation box in a way that conserves image locations. In this work, the ideas are extended to a large class of three-dimensional flows by using multiple remappings for the simulation box. The simulation box geometry is no longer time-periodic (which was shown to be impossible for uniaxial and biaxial stretching flows in the original work by Kraynik and Reinelt [Int. J. Multiphase Flow 18, 1045 (1992)]. The presented algorithm applies to all flows with nondefective flow matrices, and in particular, to uniaxial and biaxial flows.

  13. Childhood Bereavement: Psychopathology in the 2 Years Postparental Death

    ERIC Educational Resources Information Center

    Cerel, Julie; Fristad, Mary A.; Verducci, Joseph; Weller, Ronald A.; Weller, Elizabeth B.

    2006-01-01

    Objective: Although the death of a parent is one of the most significant stressors a child can experience, the psychiatric sequelae of parental death are not fully understood. Method: A total of 360 parent-bereaved children (ages 6-17) and their surviving parents were directly interviewed four times during the first 2 years following the death (at…

  14. Time-dependent Mott transition in the periodic Anderson model with nonlocal hybridization

    NASA Astrophysics Data System (ADS)

    Hofmann, Felix; Potthoff, Michael

    2016-08-01

    The time-dependent Mott transition in a periodic Anderson model with off-site, nearest-neighbor hybridization is studied within the framework of nonequilibrium self-energy functional theory. Using the two-site dynamical-impurity approximation, we compute the real-time dynamics of the optimal variational parameter and of different observables initiated by sudden quenches of the Hubbard-U and identify the critical interaction. The time-dependent transition is orbital selective, i.e., in the final state, reached in the long-time limit after the quench to the critical interaction, the Mott gap opens in the spectral function of the localized orbitals only. We discuss the dependence of the critical interaction and of the final-state effective temperature on the hybridization strength and point out the various similarities between the nonequilibrium and the equilibrium Mott transition. It is shown that these can also be smoothly connected to each other by increasing the duration of a U-ramp from a sudden quench to a quasi-static process. The physics found for the model with off-site hybridization is compared with the dynamical Mott transition in the single-orbital Hubbard model and with the dynamical crossover found for the real-time dynamics of the conventional Anderson lattice with on-site hybridization.

  15. On Bifurcating Time-Periodic Flow of a Navier-Stokes Liquid Past a Cylinder

    NASA Astrophysics Data System (ADS)

    Galdi, Giovanni P.

    2016-10-01

    We provide general sufficient conditions for the existence and uniqueness of branching out of a time-periodic family of solutions from steady-state solutions to the two-dimensional Navier-Stokes equations in the exterior of a cylinder. By separating the time-independent averaged component of the velocity field from its oscillatory one, we show that the problem can be formulated as a coupled elliptic-parabolic nonlinear system in appropriate and distinct function spaces, with the property that the relevant linearized operators become Fredholm of index 0. In this functional setting, the notorious difficulty of 0 being in the essential spectrum entirely disappears and, in fact, it is even meaningless. Our approach is different and, we believe, more natural and simpler than those proposed by previous authors discussing similar questions. Moreover, the latter all fail, when applied to the problem studied here.

  16. Period-independent novel circadian oscillators revealed by timed exercise and palatable meals

    PubMed Central

    Flôres, Danilo E. F. L.; Bettilyon, Crystal N.; Yamazaki, Shin

    2016-01-01

    The mammalian circadian system is a hierarchical network of oscillators organized to optimally coordinate behavior and physiology with daily environmental cycles. The suprachiasmatic nucleus (SCN) of the hypothalamus is at the top of this hierarchy, synchronizing to the environmental light-dark cycle, and coordinates the phases of peripheral clocks. The Period genes are critical components of the molecular timekeeping mechanism of these clocks. Circadian clocks are disabled in Period1/2/3 triple mutant mice, resulting in arrhythmic behavior in constant conditions. We uncovered rhythmic behavior in this mutant by simply exposing the mice to timed access to a palatable meal or running wheel. The emergent circadian behavior rhythms free-ran for many cycles under constant conditions without cyclic environmental cues. Together, these data demonstrate that the palatable meal-inducible circadian oscillator (PICO) and wheel-inducible circadian oscillator (WICO) are generated by non-canonical circadian clocks. Entrainment of these novel oscillators by palatable snacks and timed exercise could become novel therapeutics for human conditions caused by disruptions of the circadian clocks. PMID:26904978

  17. Enhanced Transport of Passive Tracers In A Time Periodic Two-dimensional Flow

    NASA Astrophysics Data System (ADS)

    Boffetta, G.; Cencini, M.; Espa, S.; Musacchio, S.

    , investigating systems in which the second condition is violated is much more inter- esting. With this purpose, some experiments have shown how superdiffusion arises in a two-dimensional quasi-geostrophic (planetary-type) flow, where particles can jump for very long time in the same direction performing a Levy flight (Castiglione et al., 2001 ). Moreover, two recent papers (Vulpiani, 1998; Solomon, 2001) show how, also in very simple two-dimensional, time and space periodic cellular flows,anomalous diffusive behaviours can appear. In this paper we present an experimental study of transport in an electromagnetically forced time periodic two-dimensional flow. The flow is generated by applying an electromagnetic forcing on a thin layer of an elec- trolyte solution and reveals in a square grid of alternating vortices. Time dependence can be easily obtained by changing the time dependence of the electric fields. In par- ticular, considering certain values of the imposed oscillation frequencies, particles can display very long jump. Particle Tracking Velocimetry (PTV) is used to measure the flow field. This technique is the most suitable for studying dispersion phenomena in a Lagrangian framework allowing the direct evaluation of particle displacements and related quantities (Cenedese, Querzoli; 2000). Moreover, due to the characteristics of the analyzed flow and to the improvement of the tracking procedure, we have been able to track a great number of particles for time intervals greater than the charac- teristic time-scales of the flow. In order to characterize the time correlations we will evaluate the so-called jumps probabilities with memory which represent the probabil- ities to jump in a given direction conditioned to having experienced jumps in the same direction at previous times. Such statistics will revealed very useful and suitable for detecting the onset of the aforementioned correlations. 2

  18. Evolution of illustrations in anatomy: a study from the classical period in Europe to modern times.

    PubMed

    Ghosh, Sanjib Kumar

    2015-01-01

    Illustrations constitute an essential element of learning anatomy in modern times. However it required a significant evolutionary process spread over centuries, for illustrations to achieve the present status in the subject of anatomy. This review article attempts to outline the evolutionary process by highlighting on the works of esteemed anatomists in a chronological manner. Available literature suggests that illustrations were not used in anatomy during the classical period when the subject was dominated by the descriptive text of Galen. Guido da Vigevano was first to use illustrations in anatomy during the Late Middle Ages and this concept developed further during the Renaissance period when Andreas Vesalius pioneered in illustrations becoming an indispensable tool in conveying anatomical details. Toward later stages of the Renaissance period, Fabricius ab Aquapendente endeavored to restrict dramatization of anatomical illustrations which was a prevalent trend in early Renaissance. During the 18th century, anatomical artwork was characterized by the individual styles of prominent anatomists leading to suppression of anatomical details. In the 19th century, Henry Gray used illustrations in his anatomical masterpiece that focused on depicting anatomical structures and were free from any artistic style. From early part of the 20th century medical images and photographs started to complement traditional handmade anatomical illustrations. Computer technology and advanced software systems played a key role in the evolution of anatomical illustrations during the late 20th century resulting in new generation 3D image datasets that are being used in the 21st century in innovative formats for teaching and learning anatomy. PMID:25053471

  19. Long-time asymptotics of the periodic Toda lattice under short-range perturbations

    NASA Astrophysics Data System (ADS)

    Kamvissis, Spyridon; Teschl, Gerald

    2012-07-01

    We compute the long-time asymptotics of periodic (and slightly more generally of algebro-geometric finite-gap) solutions of the doubly infinite Toda lattice under a short-range perturbation. In particular, we prove that the perturbed lattice asymptotically approaches a modulated lattice. More precisely, let g be the genus of the hyperelliptic curve associated with the unperturbed solution. We show that, apart from the phenomenon of solitons travelling in a quasi-periodic background, the n/t-pane contains g + 2 areas where the perturbed solution is close to a finite-gap solution on the same isospectral torus. In between there are g + 1 regions where the perturbed solution is asymptotically close to a modulated lattice which undergoes a continuous phase transition (in the Jacobian variety) and which interpolates between these isospectral solutions. In the special case of the free lattice (g = 0), the isospectral torus consists of just one point and we recover the known result. Both the solutions in the isospectral torus and the phase transition are explicitly characterized in terms of Abelian integrals on the underlying hyperelliptic curve. Our method relies on the equivalence of the inverse spectral problem to a vector Riemann-Hilbert problem defined on the hyperelliptic curve and generalizes the so-called nonlinear stationary phase/steepest descent method for Riemann-Hilbert problem deformations to Riemann surfaces.

  20. A General Time-Periodic Driving Approach to Realize Topological Phases in Cold Atomic Systems

    PubMed Central

    Yan, Zhongbo; Li, Bo; Yang, Xiaosen; Wan, Shaolong

    2015-01-01

    For time-reversal symmetric cold atomic insulating systems, it is found that the usual driving approach based on electromagnetic field used in solid state systems loses its power to drive them from trivial regimes to topological regimes if the driven systems still hold time-reversal symmetry (TRS). For such systems, we point out that simply varying the optical lattice potential periodically provides a general and effective way to drive them into topological regimes without breaking their symmetries. Based on this approach, we find that the time-reversal symmetric Kane-Mele model can be effectively driven from the trivial phase to topological phases named as Floquet Quantum Spin Hall insulator. Due to the existence of two gaps in the Floquet system, this novel state of matter can stably host one or two pair of gapless helical states on the same boundary, which suggests this state is not a simple analog of the Quantum Spin Hall insulator. This new driving approach to a system without TRS is also investigated. PMID:26541611

  1. Dynamical generalized Hurst exponent as a tool to monitor unstable periods in financial time series

    NASA Astrophysics Data System (ADS)

    Morales, Raffaello; Di Matteo, T.; Gramatica, Ruggero; Aste, Tomaso

    2012-06-01

    We investigate the use of the Hurst exponent, dynamically computed over a weighted moving time-window, to evaluate the level of stability/instability of financial firms. Financial firms bailed-out as a consequence of the 2007-2008 credit crisis show a neat increase with time of the generalized Hurst exponent in the period preceding the unfolding of the crisis. Conversely, firms belonging to other market sectors, which suffered the least throughout the crisis, show opposite behaviors. We find that the multifractality of the bailed-out firms increase at the crisis suggesting that the multi fractal properties of the time series are changing. These findings suggest the possibility of using the scaling behavior as a tool to track the level of stability of a firm. In this paper, we introduce a method to compute the generalized Hurst exponent which assigns larger weights to more recent events with respect to older ones. In this way large fluctuations in the remote past are less likely to influence the recent past. We also investigate the scaling associated with the tails of the log-returns distributions and compare this scaling with the scaling associated with the Hurst exponent, observing that the processes underlying the price dynamics of these firms are truly multi-scaling.

  2. A General Time-Periodic Driving Approach to Realize Topological Phases in Cold Atomic Systems

    NASA Astrophysics Data System (ADS)

    Yan, Zhongbo; Li, Bo; Yang, Xiaosen; Wan, Shaolong

    2015-11-01

    For time-reversal symmetric cold atomic insulating systems, it is found that the usual driving approach based on electromagnetic field used in solid state systems loses its power to drive them from trivial regimes to topological regimes if the driven systems still hold time-reversal symmetry (TRS). For such systems, we point out that simply varying the optical lattice potential periodically provides a general and effective way to drive them into topological regimes without breaking their symmetries. Based on this approach, we find that the time-reversal symmetric Kane-Mele model can be effectively driven from the trivial phase to topological phases named as Floquet Quantum Spin Hall insulator. Due to the existence of two gaps in the Floquet system, this novel state of matter can stably host one or two pair of gapless helical states on the same boundary, which suggests this state is not a simple analog of the Quantum Spin Hall insulator. This new driving approach to a system without TRS is also investigated.

  3. Sustained and transient attentional processes modulate neural predictors of memory encoding in consecutive time periods.

    PubMed

    Padovani, Tullia; Koenig, Thomas; Eckstein, Doris; Perrig, Walter J

    2013-07-01

    Memory formation is commonly thought to rely on brain activity following an event. Yet, recent research has shown that even brain activity previous to an event can predict later recollection (subsequent memory effect, SME). In order to investigate the attentional sources of the SME, event-related potentials (ERPs) elicited by task cues preceding target words were recorded in a switched task paradigm that was followed by a surprise recognition test. Stay trials, that is, those with the same task as the previous trial, were contrasted with switch trials, which included a task switch compared to the previous trial. The underlying assumption was that sustained attention would be dominant in stay trials and that transient attentional reconfiguration processes would be dominant in switch trials. To determine the SME, local and global statistics of scalp electric fields were used to identify differences between subsequently remembered and forgotten items. Results showed that the SME in stay trials occurred in a time window from 2 to 1 sec before target onset, whereas the SME in switch trials occurred subsequently, in a time window from 1 to 0 sec before target onset. Both SMEs showed a frontal negativity resembling the topography of previously reported effects, which suggests that sustained and transient attentional processes contribute to the prestimulus SME in consecutive time periods. PMID:24381815

  4. Multi Band Insar Analysis of Subsidence Development Based on the Long Period Time Series

    NASA Astrophysics Data System (ADS)

    Çomut, F. C.; Ustun, A.; Lazecky, M.; Aref, M. M.

    2015-12-01

    The SAR Interferometry (InSAR) application has shown great potential in monitoring of land terrain changes and in detection of land deformations such as subsidence. Longer time analysis can lead to understand longer trends and changes. Using different bands of SAR satellite (C- from ERS 1-2 and Envisat, L- from ALOS) over the study area, we achieve knowledge of movements in long-term and evaluation of its dynamic changes within observed period of time. Results from InSAR processing fit with the position changes in vertical direction based on GPS network established over the basin as an effective geodetic network. Time series (StaMPS PS+SB) of several points over Çumra County in eastern part of Konya City show a general trend of the deformation that is expected to be approximately between -13 to -17 mm/year. Northern part of Karaman is affected by faster subsidence, borders of the subsidence trough were identified from Envisat. Presenting InSAR results together with GIS information about locations and time of occurrence of sudden subsidence, urban/industrial growth in time and climate changes helps in better understanding of the situation. This way, the impact of natural and man-made changes will be shown for urban planning thanks to InSAR and GIS comparisons with hydrogeological modeling. In this study we present results of differential and multitemporal InSAR series using different bands and GIS conjunction associated with seasonal and temporal groundwater level changes in Konya Closed Basin.

  5. Periodic coupling strength-dependent multiple coherence resonance by time delay in Newman-Watts neuronal networks.

    PubMed

    Wu, Yanan; Gong, Yubing; Xu, Bo

    2013-12-01

    Recently, multiple coherence resonance induced by time delay has been observed in neuronal networks with constant coupling strength. In this paper, by employing Newman-Watts Hodgkin-Huxley neuron networks with time-periodic coupling strength, we study how the temporal coherence of spiking behavior and coherence resonance by time delay change when the frequency of periodic coupling strength is varied. It is found that delay induced coherence resonance is dependent on periodic coupling strength and increases when the frequency of periodic coupling strength increases. Periodic coupling strength can also induce multiple coherence resonance, and the coherence resonance occurs when the frequency of periodic coupling strength is approximately multiple of the spiking frequency. These results show that for periodic coupling strength time delay can more frequently optimize the temporal coherence of spiking activity, and periodic coupling strength can repetitively optimize the temporal coherence of spiking activity as well. Frequency locking may be the mechanism for multiple coherence resonance induced by periodic coupling strength. These findings imply that periodic coupling strength is more efficient for enhancing the temporal coherence of spiking activity of neuronal networks, and thus it could play a more important role in improving the time precision of information processing and transmission in neural networks.

  6. Stochastic extinction of tumor cells due to synchronization effect through time periodic treatment in a tumor-immune interaction model

    NASA Astrophysics Data System (ADS)

    Aisu, Ryota; Horita, Takehiko

    The response to a time periodic treatment of the immunotherapy in a stochastic model of tumor-immune interaction is numerically investigated. Due to the effect of synchronization among the intrinsic oscillation and the treatment, an enhanced extinction of the tumor cells is observed. It suggests that compared with the static treatment, by controlling the period of the treatment, the time periodic treatment could be an effective way of treatment leading to tumor extinction.

  7. Crossing rule for a PT-symmetric two-level time-periodic system

    SciTech Connect

    Moiseyev, Nimrod

    2011-05-15

    For a two-level system in a time-periodic field we show that in the non-Hermitian PT case the level crossing is of two quasistationary states that have the same dynamical symmetry property. At the field's parameters where the two levels which have the same dynamical symmetry cross, the corresponding quasienergy states coalesce and a self-orthogonal state is obtained. This situation is very different from the Hermitian case where a crossing of two quasienergy levels happens only when the corresponding two quasistationary states have different dynamical symmetry properties and, unlike the situation in the non-Hermitian case, the spectrum remains complete also when the two levels cross.

  8. Fluctuation relations for heat engines in time-periodic steady states

    NASA Astrophysics Data System (ADS)

    Lahiri, Sourabh; Rana, Shubhashis; Jayannavar, A. M.

    2012-11-01

    A fluctuation relation for heat engines has been derived recently. In the beginning, the system is in contact with the cooler bath. The system is then coupled to the hotter bath and external parameters are changed cyclically, eventually bringing the system back to its initial state, once the coupling with the hot bath is switched off. In this work, we lift the condition of initial thermal equilibrium and derive a new fluctuation relation for the central system (heat engine) being in a time-periodic steady state (TPSS). Carnot’s inequality for classical thermodynamics follows as a direct consequence of this fluctuation theorem even in the TPSS. For the special cases of the absence of hot bath and no extraction of work, we obtain the integral fluctuation theorem for total entropy and the generalized exchange fluctuation theorem, respectively. Recently, microsized heat engines have been realized experimentally in the TPSS. We numerically simulate the same model and verify our proposed theorems.

  9. Efficiency, Power and Period of a model quantum heat engine working in a finite time

    NASA Astrophysics Data System (ADS)

    Bekele, Mulugeta; Dima, Tolasa A.; Alemye, Mekuannent; Chegeno, Warga

    We take a spin-half quantum particle undergoing Carnot type cyclic process in a finite time assisted by two heat reservoirs and an external magnetic field. We find that the power of the heat engine is maximum at a particular period of the cyclic process and efficiency at the maximum power is at least half of the Carnot efficiency. We further apply the Omega-criterion for a figure of merit representing a compromise between useful power and lost power determining the corresponding efficiency for the optimization criterion to be at least three fourth of the Carnot efficiency. The authers are thankful to the International Science programme, IPS, Uppsala, Sweden for their support to our research lab.

  10. Controllability discrepancy and irreducibility/reducibility of Floquet factorisations in linear continuous-time periodic systems

    NASA Astrophysics Data System (ADS)

    Zhou, Jun; Lu, Xinbiao; Qian, Huimin

    2016-09-01

    The paper reports interesting but unnoticed facts about irreducibility (resp., reducibility) of Flouqet factorisations and their harmonic implication in term of controllability in finite-dimensional linear continuous-time periodic (FDLCP) systems. Reducibility and irreducibility are attributed to matrix logarithm algorithms during computing Floquet factorisations in FDLCP systems, which are a pair of essential features but remain unnoticed in the Floquet theory so far. The study reveals that reducible Floquet factorisations may bring in harmonic waves variance into the Fourier analysis of FDLCP systems that in turn may alter our interpretation of controllability when the Floquet factors are used separately during controllability testing; namely, controllability interpretation discrepancy (or simply, controllability discrepancy) may occur and must be examined whenever reducible Floquet factorisations are involved. On the contrary, when irreducible Floquet factorisations are employed, controllability interpretation discrepancy can be avoided. Examples are included to illustrate such observations.

  11. Intercomparison of UT1 measurements during the MERIT campaign period. [Universal Time

    NASA Technical Reports Server (NTRS)

    Spieth, M. A.; Eubanks, T. M.; Steppe, J. A.

    1986-01-01

    Universal time (UT1) measurements obtained using VLBI, lunar laser ranging (LLR), and BIH optical astronomy are compared. The JPL Kalman filter for the earth rotation and the polar motion is utilized to smooth one data set or combine data sets for intercomparison. The differences between raw UT1 data and independently smoothed data are employed to assess the accuracy of the measured series and the sufficiency of the error budget. Systematic errors in periodic signatures and length of day estimates are analyzed. The data reveal that the techniques of LLR and VLBI agree to within their formal errors. It is determined that the residual error for the LLR is too large and the residual error estimated for the BIH data is too small.

  12. Observations of the April 2002 Storm Period with TIMED-TIDI

    NASA Astrophysics Data System (ADS)

    Niciejewski, R.; Killeen, T.; Wu, Q.; Skinner, W.; Solomon, S.; Ortland, D.; Kafkalidis, J.; Gell, D.; Gablehouse, D.; Johnson, R.

    2002-12-01

    TIDI is meeting its basic requirement, which is to measure the global wind field in the mesosphere and lower thermosphere, the core study region. Since February 2002, TIDI has been in a routine science data-taking mode. During April 2002, TIMED was positioned at a high beta angle (angle between the plane of the satellite orbit and the Earth-Sun line) resulting in a series of TIDI measurements near the dusk/dawn terminator. The field of view of TIDI allows it to obtain measurements from pole to pole, while the repetition rate of the sky-scanner allows it to obtain several scans within the auroral oval region on each orbit. This paper will discuss TIDI measurements obtained during the April 2002 storm period, including OI (5577\\x8F) intensity data and neutral wind data sets.

  13. 40 CFR 270.215 - How are time periods in the requirements in this subpart and my RAP computed?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... requirements in this subpart and my RAP computed? 270.215 Section 270.215 Protection of Environment... HAZARDOUS WASTE PERMIT PROGRAM Remedial Action Plans (RAPs) Operating Under Your Rap § 270.215 How are time periods in the requirements in this subpart and my RAP computed? (a) Any time period scheduled to begin...

  14. 40 CFR 270.215 - How are time periods in the requirements in this subpart and my RAP computed?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements in this subpart and my RAP computed? 270.215 Section 270.215 Protection of Environment... HAZARDOUS WASTE PERMIT PROGRAM Remedial Action Plans (RAPs) Operating Under Your Rap § 270.215 How are time periods in the requirements in this subpart and my RAP computed? (a) Any time period scheduled to begin...

  15. 40 CFR 270.215 - How are time periods in the requirements in this subpart and my RAP computed?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... requirements in this subpart and my RAP computed? 270.215 Section 270.215 Protection of Environment... HAZARDOUS WASTE PERMIT PROGRAM Remedial Action Plans (RAPs) Operating Under Your Rap § 270.215 How are time periods in the requirements in this subpart and my RAP computed? (a) Any time period scheduled to begin...

  16. 40 CFR 270.215 - How are time periods in the requirements in this subpart and my RAP computed?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements in this subpart and my RAP computed? 270.215 Section 270.215 Protection of Environment... HAZARDOUS WASTE PERMIT PROGRAM Remedial Action Plans (RAPs) Operating Under Your Rap § 270.215 How are time periods in the requirements in this subpart and my RAP computed? (a) Any time period scheduled to begin...

  17. 40 CFR 270.215 - How are time periods in the requirements in this subpart and my RAP computed?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirements in this subpart and my RAP computed? 270.215 Section 270.215 Protection of Environment... HAZARDOUS WASTE PERMIT PROGRAM Remedial Action Plans (RAPs) Operating Under Your Rap § 270.215 How are time periods in the requirements in this subpart and my RAP computed? (a) Any time period scheduled to begin...

  18. The timing and duration of a sensitive period in human flavor learning: a randomized trial1234

    PubMed Central

    Mennella, Julie A; Lukasewycz, Laura D; Castor, Sara M; Beauchamp, Gary K

    2011-01-01

    Background: By using the response to protein hydrolysate formula (PHF) as a model system, we discovered the existence of a sensitive period, before 4 mo, when exposure determines the hedonic tone to flavors. Objective: We aimed to characterize the timing and duration of this sensitive period. Design: Healthy infants, whose parents had chosen formula feeding, were randomly assigned into 1 of 6 groups at age 0.5 mo: 2 control groups, one fed cow milk–based formula (CMF) and the other fed PHF for 7 mo; 2 groups fed PHF for either 1 or 3 mo beginning at 1.5 mo and CMF otherwise; and 2 groups fed PHF for 1 mo beginning at either 2.5 or 3.5 mo and CMF otherwise. Brief access taste tests were conducted monthly, and complete “meals” of both formulas occurred at the end of the study. Results: Three months of PHF exposure led to acceptance similar to that at 1 mo of exposure. Although these infants were more accepting than were infants with no exposure, they were less accepting than were infants with 7 mo of exposure, which suggests a dosing effect. The time when flavor experiences began was also significant. Among infants exposed to PHF for 1 mo, those who were first fed PHF at 3.5 mo rejected PHF relative to CMF more than did infants exposed at younger ages. Conclusion: The general principles observed are likely of broader significance, indicating a fundamental feature of mammalian development and reflecting the importance of familiarizing infants with flavors that their mothers consume and transmit to breast milk. This trial was registered at clinicaltrials.gov as NCT00994747. PMID:21310829

  19. Low-thrust roundtrip trajectories to Mars with one-synodic-period repeat time

    NASA Astrophysics Data System (ADS)

    Okutsu, Masataka; Landau, Damon F.; Rogers, Blake A.; Longuski, James M.

    2015-05-01

    Cycler trajectories-both ballistic and powered-are reported in the literature in which there are two-vehicle, three-vehicle, and four-vehicle cases. Such trajectories permit the installation of cycler vehicles which provide safe and comfortable living conditions for human space travel between Earth and Mars during every synodic opportunity. The question the present paper answers is a logical, obvious one: Does a single-vehicle, one-synodic-period cycler exist? The answer is yes: such a trajectory can be flown-but only with a high-power electric propulsion system. In our example, it is found that "stopover" trajectories that spend 30 days in orbit about Earth and 30 days about Mars, and return astronauts to Earth in one synodic period require a 90-t power generator with a power level of 11 MWe. Fortuitously, and in lieu of using chemical propulsion, the high power level of the electric propulsion system would also be effective in hauling the cargo payload via a spiral trajectory about the Earth. But because one synodic period is not enough for the cycler vehicle to fly both the interplanetary trajectories and the Earth-spiral trajectories, we suggest developing two nuclear power generators, which could alternate flying the interplanetary trajectories and the Earth-spiral trajectories. Once these power generators are launched and begin operating in space, the mass requirement in seven subsequent missions (over a period of 15 years beginning in 2022) would be modest at 250-300 metric tons to low-Earth orbit per mission. Thus two cargo launches of NASA's Space Launch System and one crew launch of the Falcon Heavy, for example, would be adequate to maintain support for each consecutive mission. Although we propose developing two sets of electric propulsion systems to account for the Earth-spiral phases, only one vehicle is flown on a heliocentric trajectory at any given time. Thus, our low-thrust stopover cycler with zero encounter velocities falls into a category of a

  20. Mapping Longitudinal Development of Local Cortical Gyrification in Infants from Birth to 2 Years of Age

    PubMed Central

    Li, Gang; Wang, Li; Shi, Feng; Lyall, Amanda E.; Lin, Weili; Gilmore, John H.

    2014-01-01

    Human cortical folding is believed to correlate with cognitive functions. This likely correlation may have something to do with why abnormalities of cortical folding have been found in many neurodevelopmental disorders. However, little is known about how cortical gyrification, the cortical folding process, develops in the first 2 years of life, a period of dynamic and regionally heterogeneous cortex growth. In this article, we show how we developed a novel infant-specific method for mapping longitudinal development of local cortical gyrification in infants. By using this method, via 219 longitudinal 3T magnetic resonance imaging scans from 73 healthy infants, we systemically and quantitatively characterized for the first time the longitudinal cortical global gyrification index (GI) and local GI (LGI) development in the first 2 years of life. We found that the cortical GI had age-related and marked development, with 16.1% increase in the first year and 6.6% increase in the second year. We also found marked and regionally heterogeneous cortical LGI development in the first 2 years of life, with the high-growth regions located in the association cortex, whereas the low-growth regions located in sensorimotor, auditory, and visual cortices. Meanwhile, we also showed that LGI growth in most cortical regions was positively correlated with the brain volume growth, which is particularly significant in the prefrontal cortex in the first year. In addition, we observed gender differences in both cortical GIs and LGIs in the first 2 years, with the males having larger GIs than females at 2 years of age. This study provides valuable information on normal cortical folding development in infancy and early childhood. PMID:24647943

  1. Estimating interevent time distributions from finite observation periods in communication networks

    NASA Astrophysics Data System (ADS)

    Kivelä, Mikko; Porter, Mason A.

    2015-11-01

    A diverse variety of processes—including recurrent disease episodes, neuron firing, and communication patterns among humans—can be described using interevent time (IET) distributions. Many such processes are ongoing, although event sequences are only available during a finite observation window. Because the observation time window is more likely to begin or end during long IETs than during short ones, the analysis of such data is susceptible to a bias induced by the finite observation period. In this paper, we illustrate how this length bias is born and how it can be corrected without assuming any particular shape for the IET distribution. To do this, we model event sequences using stationary renewal processes, and we formulate simple heuristics for determining the severity of the bias. To illustrate our results, we focus on the example of empirical communication networks, which are temporal networks that are constructed from communication events. The IET distributions of such systems guide efforts to build models of human behavior, and the variance of IETs is very important for estimating the spreading rate of information in networks of temporal interactions. We analyze several well-known data sets from the literature, and we find that the resulting bias can lead to systematic underestimates of the variance in the IET distributions and that correcting for the bias can lead to qualitatively different results for the tails of the IET distributions.

  2. Estimating interevent time distributions from finite observation periods in communication networks.

    PubMed

    Kivelä, Mikko; Porter, Mason A

    2015-11-01

    A diverse variety of processes-including recurrent disease episodes, neuron firing, and communication patterns among humans-can be described using interevent time (IET) distributions. Many such processes are ongoing, although event sequences are only available during a finite observation window. Because the observation time window is more likely to begin or end during long IETs than during short ones, the analysis of such data is susceptible to a bias induced by the finite observation period. In this paper, we illustrate how this length bias is born and how it can be corrected without assuming any particular shape for the IET distribution. To do this, we model event sequences using stationary renewal processes, and we formulate simple heuristics for determining the severity of the bias. To illustrate our results, we focus on the example of empirical communication networks, which are temporal networks that are constructed from communication events. The IET distributions of such systems guide efforts to build models of human behavior, and the variance of IETs is very important for estimating the spreading rate of information in networks of temporal interactions. We analyze several well-known data sets from the literature, and we find that the resulting bias can lead to systematic underestimates of the variance in the IET distributions and that correcting for the bias can lead to qualitatively different results for the tails of the IET distributions. PMID:26651750

  3. The Effects of Time-Periodic Shear on a Diffusion Flame Anchored to a Model Propellant

    NASA Astrophysics Data System (ADS)

    Isfahani, Amir H. G.; Zhang, Ju; Jackson, Thomas L.

    2008-11-01

    Propellants of solid rocket motors are subject to intense time-dependent shear flows and the response of the combustion field to these flows is of fundamental interest. Erosive burning (EB), the enhanced regression rate that can arise due to these flows, affects the performance of the solid rocket motor: the specific-impulse history. It is generally agreed that EB results from an increased heat transfer to the surface. The geometry is that of two quarter-planes of ammonium perchlorate (AP) and binder (or a blend of AP/binder). Three step kinetics is considered: AP decomposition and two diffusion flames, one between the virgin AP gases and binder and one between AP decomposed gases and binder. Gas and solid phases are coupled and temperature along the surface as well as the burn rate is solved for. We present an estimation of the shear parameters as a function of the motor size using a 2D planar periodic rocket (PPR) analysis without resorting to fully time-dependent three-dimensional turbulent simulations. These parameters are then used to study the change in the heat flux to the surface and the burn rate. It is shown that the burn rate is increased by more than two folds for larger amplitudes and frequencies.

  4. Estimating interevent time distributions from finite observation periods in communication networks.

    PubMed

    Kivelä, Mikko; Porter, Mason A

    2015-11-01

    A diverse variety of processes-including recurrent disease episodes, neuron firing, and communication patterns among humans-can be described using interevent time (IET) distributions. Many such processes are ongoing, although event sequences are only available during a finite observation window. Because the observation time window is more likely to begin or end during long IETs than during short ones, the analysis of such data is susceptible to a bias induced by the finite observation period. In this paper, we illustrate how this length bias is born and how it can be corrected without assuming any particular shape for the IET distribution. To do this, we model event sequences using stationary renewal processes, and we formulate simple heuristics for determining the severity of the bias. To illustrate our results, we focus on the example of empirical communication networks, which are temporal networks that are constructed from communication events. The IET distributions of such systems guide efforts to build models of human behavior, and the variance of IETs is very important for estimating the spreading rate of information in networks of temporal interactions. We analyze several well-known data sets from the literature, and we find that the resulting bias can lead to systematic underestimates of the variance in the IET distributions and that correcting for the bias can lead to qualitatively different results for the tails of the IET distributions.

  5. Time Dependence of Anodal and Cathodal Refractory Periods in Cardiac Tissue

    NASA Astrophysics Data System (ADS)

    Bennett, Jonathan A.; Roth, Bradley J.

    1997-11-01

    Cathodal and anodal make and break excitation have been observed in cardiac tissue. Make excitation occurs when a stimulus pulse is turned on and has a lower threshold than break excitation, which occurs when a stimulus pulse is turned off. Mehra et al. (PACE 3:526) observed that over time the anodal refractory period (RP) becomes longer than the cathodal RP. After implantation, damaged tissue accumulates around the electrode, thereby increasing its effective surface area. We investigate this time-dependent change numerically by stimulating cardiac tissue using small and large electrodes. The tissue is represented as a bidomain with a Beeler-Reuter membrane. Like Mehra et al., we define the RP to be the threshold interval at a strength of 8 mA. The anodal RP is longer than the cathodal RP for the large electrode, whereas it is shorter for the small electrode. However, anode break threshold for the small electrode is less than 8 mA, but for the large electrode it is greater than 8 mA. The lengthening of the anodal RP is caused by excluding the anode break excitation with the larger electrode. This result is consistent with Mehra et al., and suggests that their observation resulted from their definition of RP.

  6. Growth mechanism of photoreduced silver nanostructures on periodically proton exchanged lithium niobate: Time and concentration dependence

    SciTech Connect

    Craig Carville, N.; Denning, Denise; Rodriguez, Brian J.; Manzo, Michele; Gallo, Katia

    2013-05-14

    Photodeposition of metallic nanostructures onto ferroelectric surfaces, which have been chemically patterned using a proton exchange process, has recently been demonstrated. By varying the molar concentration of the AgNO{sub 3} solution and the illumination time, one can determine the initial nucleation sites, control the rate of nucleation and the height of silver nanostructures formed, and study the mechanisms by which these processes occurs. The nanoparticles are found to deposit preferentially in the boundary between ferroelectric and proton exchanged regions, in an area proton exchanged via lateral diffusion under the masking layer used for chemical patterning, consistent with our previous results. Using a short illumination time (3 min), we are able to determine that the initial nucleation of the silver nanostructure, having a width of 0.17 {+-} 0.02 {mu}m and a height of 1.61 {+-} 0.98 nm, occurs near the edge of the reactive ion etched area within this lateral diffusion region. Over longer illumination times (15 min), we find that the silver deposition has spread to a width of 1.29 {+-} 0.06 {mu}m, extending across the entire lateral diffusion region. We report that at a high molar concentration of AgNO{sub 3} (10{sup -2} M), the amount of silver deposition for 5 min UV illumination is greater (2.88 {+-} 0.58 nm) compared to that at low (10{sup -4} M) concentrations (0.78 {+-} 0.35 nm), however, this is not the case for longer time periods. With increasing illumination time (15 min), experiments at 10{sup -4} M had greater overall deposition, 6.90 {+-} 1.52 nm, compared to 4.50 {+-} 0.76 nm at 10{sup -2} M. For longer exposure times (30 min) at 10{sup -2} M, the nanostructure height is 4.72 {+-} 0.59 nm, suggesting a saturation in the nanostructure height. The results are discussed in terms of the electric double layer that forms at the crystal surface. There is an order of magnitude difference between the Debye lengths for 10{sup -2} and 10{sup -4} M

  7. Almost periodic solutions for a memristor-based neural networks with leakage, time-varying and distributed delays.

    PubMed

    Jiang, Ping; Zeng, Zhigang; Chen, Jiejie

    2015-08-01

    In this paper, we study the existence and global exponential stability of almost periodic solution for memristor-based neural networks with leakage, time-varying and distributed delays. Using a new Lyapunov function method, we prove that this delayed neural network has a unique almost periodic solution, which is globally exponentially stable. Moreover, the obtained conclusion on the almost periodic solution is applied to prove the existence and stability of periodic solution (or equilibrium point) for this delayed neural network with periodic coefficients (or constant coefficients).

  8. Timing and return period of major palaeoseismic events in the Shillong Plateau, India

    NASA Astrophysics Data System (ADS)

    Sukhija, B. S.; Rao, M. N.; Reddy, D. V.; Nagabhushanam, P.; Hussain, Syed; Chadha, R. K.; Gupta, H. K.

    1999-07-01

    The close temporal occurrence of four great earthquakes in the past century, including the great Assam earthquake of 1897 in the Shillong Plateau, necessitated examination of the palaeoseismicity of the region. The results from such investigation would definitely aid in addressing the problem of the earthquake hazard evaluation more realistically. Our recent palaeoseismological study in the Shillong Plateau has led us to identify and provide geological evidence for large/major earthquakes and estimate the probable recurrence period of such violent earthquakes in parts of the Shillong Plateau and the adjoining Brahmaputra valley. Trenching along the Krishnai River, a tributary of the River Brahmaputra, has unravelled very conspicuous and significant earthquake-induced signatures in the alluvial deposits of the valley. The geological evidence includes: (1) palaeoliquefaction features, like sand dykes and sand blows; (2) deformational features, like tilted beds; (3) fractures and syndepositional deformational features, like flame structures caused by coeval seismic events. Chronological constraints of the past large/major earthquakes are provided from upper and lower radiocarbon age bounds in the case of the palaeoliquefaction features, and the coeval timing of the palaeoseismic events is obtained from the radiocarbon dating of the organic material associated with the deformed horizon as well as buried tree trunks observed wide distances apart. Our palaeoseismic measurements, which are the first from the area, indicate that the Shillong Plateau has been struck by large/major earthquakes around 500±150, 1100±150 and >1500±150 yr BP, in addition to the well-known great seismic event of 1897, thereby the 14C dates indicate a recurrence period of the order of 500 yr for large earthquakes in the Shillong Plateau.

  9. Identification of Under-Detected Periodicity in Time-Series Microarray Data by Using Empirical Mode Decomposition

    PubMed Central

    Chen, Chaang-Ray; Shu, Wun-Yi; Chang, Cheng-Wei; Hsu, Ian C.

    2014-01-01

    Detecting periodicity signals from time-series microarray data is commonly used to facilitate the understanding of the critical roles and underlying mechanisms of regulatory transcriptomes. However, time-series microarray data are noisy. How the temporal data structure affects the performance of periodicity detection has remained elusive. We present a novel method based on empirical mode decomposition (EMD) to examine this effect. We applied EMD to a yeast microarray dataset and extracted a series of intrinsic mode function (IMF) oscillations from the time-series data. Our analysis indicated that many periodically expressed genes might have been under-detected in the original analysis because of interference between decomposed IMF oscillations. By validating a protein complex coexpression analysis, we revealed that 56 genes were newly determined as periodic. We demonstrated that EMD can be used incorporating with existing periodicity detection methods to improve their performance. This approach can be applied to other time-series microarray studies. PMID:25372711

  10. The last interglacial period on the Pacific Coast of North America: Timing and paleoclimate

    USGS Publications Warehouse

    Muhs, D.R.; Simmons, K.R.; Kennedy, G.L.; Rockwell, T.K.

    2002-01-01

    New, high-precision U-series ages of solitary corals (Balanophyllia elegans) coupled with molluscan faunal data from marine terraces on the Pacific Coast of North America yield information about the timing and warmth of the last interglacial sea-level highstand. Balanophyllia elegans takes up U in isotopic equilibrium with seawater during growth and shortly after death. Corals from the second terrace on San Clemente Island (offshore southern California), the third terrace on Punta Banda (on the Pacific Coast of northern Baja California), and the Discovery Point Formation on Isla de Guadalupe (in the Pacific Ocean offshore Baja California) date to the peak of the last interglacial period and have U-series ages ranging from ca. 123 to 114 ka. The first terrace on Punta Banda has corals with ages ranging from ca. 83 to 80 ka, which corresponds to a sea-level highstand formed in the late last interglacial period. U-series analyses of corals from the Cayucos terrace (central California) and the Nestor terrace at Point Loma (southern California) show that these fossils have evidence of open-system history, similar to what has been reported by other workers for the same localities. Nevertheless, a model of continuous, secondary U and Th uptake shows that two ages of corals are likely present at these localities, representing the ca. 105 and ca. 120 ka sea-level highstands reported elsewhere. U-series ages of last interglacial corals from the Pacific Coast overlap with, but are on average younger than the ages of corals from Barbados, the Bahamas, and Hawaii. This age difference is explained by the nature of the geomorphic response to sea-level change: fringing or barrier reefs on low-latitude coastlines have an accretionary growth style that keeps pace with rising sea level, whether on a tectonically rising or stable coastline. In contrast, midlatitude, high-energy coastlines are sites of platform cutting during the early part of a sea-level high stand and terrace

  11. Time-Based Measurement of Personal Mite Allergen Bioaerosol Exposure over 24 Hour Periods.

    PubMed

    Tovey, Euan R; Liu-Brennan, Damien; Garden, Frances L; Oliver, Brian G; Perzanowski, Matthew S; Marks, Guy B

    2016-01-01

    Allergic diseases such as asthma and rhinitis are common in many countries. Globally the most common allergen associated with symptoms is produced by house dust mites. Although the bed has often been cited as the main site of exposure to mite allergens, surprisingly this has not yet been directly established by measurement due to a lack of suitable methods. Here we report on the development of novel methods to determine the pattern of personal exposure to mite allergen bioaerosols over 24-hour periods and applied this in a small field study using 10 normal adults. Air was sampled using a miniature time-based air-sampler of in-house design located close to the breathing zone of the participants, co-located with a miniature time-lapse camera. Airborne particles, drawn into the sampler at 2L/min via a narrow slot, were impacted onto the peripheral surface of a disk mounted on the hour-hand of either a 12 or 24 hour clock motor. The impaction surface was either an electret cloth, or an adhesive film; both novel for these purposes. Following a review of the time-lapse images, disks were post-hoc cut into subsamples corresponding to eight predetermined categories of indoor or outdoor location, extracted and analysed for mite allergen Der p 1 by an amplified ELISA. Allergen was detected in 57.2% of the total of 353 subsamples collected during 20 days of sampling. Exposure patterns varied over time. Higher concentrations of airborne mite allergen were typically measured in samples collected from domestic locations in the day and evening. Indoor domestic Der p 1 exposures accounted for 59.5% of total exposure, whereas total in-bed-asleep exposure, which varied 80 fold between individuals, accounted overall for 9.85% of total exposure, suggesting beds are not often the main site of exposure. This study establishes the feasibility of novel methods for determining the time-geography of personal exposure to many bioaerosols and identifies new areas for future technical

  12. Time-Based Measurement of Personal Mite Allergen Bioaerosol Exposure over 24 Hour Periods

    PubMed Central

    Tovey, Euan R.; Liu-Brennan, Damien; Garden, Frances L.; Oliver, Brian G.; Perzanowski, Matthew S.; Marks, Guy B.

    2016-01-01

    Allergic diseases such as asthma and rhinitis are common in many countries. Globally the most common allergen associated with symptoms is produced by house dust mites. Although the bed has often been cited as the main site of exposure to mite allergens, surprisingly this has not yet been directly established by measurement due to a lack of suitable methods. Here we report on the development of novel methods to determine the pattern of personal exposure to mite allergen bioaerosols over 24-hour periods and applied this in a small field study using 10 normal adults. Air was sampled using a miniature time-based air-sampler of in-house design located close to the breathing zone of the participants, co-located with a miniature time-lapse camera. Airborne particles, drawn into the sampler at 2L/min via a narrow slot, were impacted onto the peripheral surface of a disk mounted on the hour-hand of either a 12 or 24 hour clock motor. The impaction surface was either an electret cloth, or an adhesive film; both novel for these purposes. Following a review of the time-lapse images, disks were post-hoc cut into subsamples corresponding to eight predetermined categories of indoor or outdoor location, extracted and analysed for mite allergen Der p 1 by an amplified ELISA. Allergen was detected in 57.2% of the total of 353 subsamples collected during 20 days of sampling. Exposure patterns varied over time. Higher concentrations of airborne mite allergen were typically measured in samples collected from domestic locations in the day and evening. Indoor domestic Der p 1 exposures accounted for 59.5% of total exposure, whereas total in-bed-asleep exposure, which varied 80 fold between individuals, accounted overall for 9.85% of total exposure, suggesting beds are not often the main site of exposure. This study establishes the feasibility of novel methods for determining the time-geography of personal exposure to many bioaerosols and identifies new areas for future technical

  13. Technical performance reduces during the extra-time period of professional soccer match-play.

    PubMed

    Harper, Liam D; West, Daniel J; Stevenson, Emma; Russell, Mark

    2014-01-01

    Despite the importance of extra-time in determining progression in specific soccer tournament matches, few studies have profiled the demands of 120-minutes of soccer match-play. With a specific focus on the extra-time period, and using a within-match approach, we examined the influence of prolonged durations of professional soccer match-play on markers of technical (i.e., skilled) performance. In 18 matches involving professional European teams played between 2010 and 2014, this retrospective study quantified the technical actions observed during eight 15-minute epochs (E1: 00∶00-14∶59 min, E2: 15∶00-29∶59 min, E3: 30∶00-44∶59 min, E4: 45∶00-59∶59 min, E5: 60∶00-74∶59 min, E6: 75∶00-89∶59 min, E7: 90∶00-104∶59 min, E8: 105∶00-119∶59 min). Analysis of players who completed the demands of the full 120 min of match-play revealed that the cumulative number of successful passes observed during E8 (61±23) was lower than E1-4 (E1: 88±23, P = 0.001; E2: 77±21, P = 0.005; E3: 79±18, P = 0.001; E4: 80±21, P = 0.001) and E7 (73±20, P = 0.002). Similarly, the total number of passes made in E8 (71±25) was reduced when compared to E1 (102±22, P = 0.001), E3 (91±19, P = 0.002), E4 (93±22, P≤0.0005) and E7 (84±20, P = 0.001). The cumulative number of successful dribbles reduced in E8 (9±4) when compared to E1 (14±4, P = 0.001) and E3 (12±4, P≤0.0005) and the total time the ball was in play was less in E8 (504±61 s) compared to E1 (598±70 s, P≤0.0005). These results demonstrate that match-specific factors reduced particular indices of technical performance in the second half of extra-time. Interventions that seek to maintain skilled performance throughout extra-time warrant further investigation.

  14. The variations of long time period slow slip events along the Ryukyu subduction zone

    NASA Astrophysics Data System (ADS)

    Tu, Y. T.; Heki, K.

    2014-12-01

    Slow slip events (SSEs) are a type of slow earthquakes that can be observed with Global Positioning System (GPS) networks in the world. Those events are detected on intensely coupled plate boundaries such as Cascadia subduction zone (Dragert et al., 2001), western North America, Mexico (Kostoglodov et al., 2003), Alaska (Ohta et al., 2007) and Tokai and Boso areas (Ozawa et al., 2002, 2003), central Japan and are considered to have relations to large subduction thrust earthquakes. However, in southwestern Ryukyu trench where most of researchers believe that it should be a decoupled plate boundary, SSEs recur regularly and are located at a patch that is as deep as 20 to 40 km (Heki and Kataoka, 2008). For comprehending the characteristics and time variations of SSEs in this area, the GEONET GPS data of 16 years are used in this study. During 1997 to 2014, more than thirty SSEs are identified near Hateruma Island, Ryukyu. The average recurrence interval is calculated to be 6.3 months and release seismic moment is Mw 6.6 on average. However, the values of recurrence interval are not invariable. From 1997 to 2002, interval period of SSEs is 7.5 months, but during 2002 to 2008, the interval period decreases suddenly to 5.5 months. After 2008, the value restores to 7.2 months again. Furthermore, the slip amount of SSEs in this area varies with time. From 1997 to 2002, the slip is 9.5 cm/year; and during 2002 to 2008, the value slightly increases to 10.5 cm/year. However, in 2008 to 2013, the slip drops to 6.6 cm/year, but accord to the trend of cumulative slip, the slip value would increase in 2014. Considering these data, we find the slip values increase conspicuously in 2002 and 2013. Coincidentally, one Mw 7.1 thrust earthquake occurred in 2002 and earthquake swarm activity started in the Okinawa trough approximately 50km north of the SSE patch. In 2013, another earthquake swarm activity occurred in nearly the same area as the 2002 activity. This suggests that the

  15. Estimating return periods of extreme values from relatively short time series of winds

    NASA Astrophysics Data System (ADS)

    Jonasson, Kristjan; Agustsson, Halfdan; Rognvaldsson, Olafur; Arfeuille, Gilles

    2013-04-01

    An important factor for determining the prospect of individual wind farm sites is the frequency of extreme winds at hub height. Here, extreme winds are defined as the value of the highest 10 minutes averaged wind speed with a 50 year return period, i.e. annual exceeding probability of 2% (Rodrigo, 2010). A frequently applied method to estimate winds in the lowest few hundred meters above ground is to extrapolate observed 10-meter winds logarithmically to higher altitudes. Recent study by Drechsel et al. (2012) showed however that this methodology is not as accurate as interpolating simulated results from the global ECMWF numerical weather prediction (NWP) model to the desired height. Observations of persistent low level jets near Colima in SW-Mexico also show that the logarithmic approach can give highly inaccurate results for some regions (Arfeuille et al., 2012). To address these shortcomings of limited, and/or poorly representative, observations and extrapolations of winds one can use NWP models to dynamically scale down relatively coarse resolution atmospheric analysis. In the case of limited computing resources one has typically to make a compromise between spatial resolution and the duration of the simulated period, both of which can limit the quality of the wind farm siting. A common method to estimate maximum winds is to fit an extreme value distribution (e.g. Gumbel, gev or Pareto) to the maximum values of each year of available data, or the tail of these values. If data are only available for a short period, e.g. 10 or 15 years, then this will give a rather inaccurate estimate. It is possible to deal with this problem by utilizing monthly or weekly maxima, but this introduces new problems: seasonal variation, autocorrelation of neighboring values, and increased discrepancy between data and fitted distribution. We introduce a new method to estimate return periods of extreme values of winds at hub height from relatively short time series of winds, simulated

  16. Dynamics of landslide model with time delay and periodic parameter perturbations

    NASA Astrophysics Data System (ADS)

    Kostić, Srđan; Vasović, Nebojša; Franović, Igor; Jevremović, Dragutin; Mitrinovic, David; Todorović, Kristina

    2014-09-01

    In present paper, we analyze the dynamics of a single-block model on an inclined slope with Dieterich-Ruina friction law under the variation of two new introduced parameters: time delay Td and initial shear stress μ. It is assumed that this phenomenological model qualitatively simulates the motion along the infinite creeping slope. The introduction of time delay is proposed to mimic the memory effect of the sliding surface and it is generally considered as a function of history of sliding. On the other hand, periodic perturbation of initial shear stress emulates external triggering effect of long-distant earthquakes or some non-natural vibration source. The effects of variation of a single observed parameter, Td or μ, as well as their co-action, are estimated for three different sliding regimes: β < 1, β = 1 and β > 1, where β stands for the ratio of long-term to short-term stress changes. The results of standard local bifurcation analysis indicate the onset of complex dynamics for very low values of time delay. On the other side, numerical approach confirms an additional complexity that was not observed by local analysis, due to the possible effect of global bifurcations. The most complex dynamics is detected for β < 1, with a complete Ruelle-Takens-Newhouse route to chaos under the variation of Td, or the co-action of both parameters Td and μ. These results correspond well with the previous experimental observations on clay and siltstone with low clay fraction. In the same regime, the perturbation of only a single parameter, μ, renders the oscillatory motion of the block. Within the velocity-independent regime, β = 1, the inclusion and variation of Td generates a transition to equilibrium state, whereas the small oscillations of μ induce oscillatory motion with decreasing amplitude. The co-action of both parameters, in the same regime, causes the decrease of block's velocity. As for β > 1, highly-frequent, limit-amplitude oscillations of initial

  17. Generational and Time Period Differences in American Adolescents’ Religious Orientation, 1966–2014

    PubMed Central

    Twenge, Jean M.; Exline, Julie J.; Grubbs, Joshua B.; Sastry, Ramya; Campbell, W. Keith

    2015-01-01

    In four large, nationally representative surveys (N = 11.2 million), American adolescents and emerging adults in the 2010s (Millennials) were significantly less religious than previous generations (Boomers, Generation X) at the same age. The data are from the Monitoring the Future studies of 12th graders (1976–2013), 8th and 10th graders (1991–2013), and the American Freshman survey of entering college students (1966–2014). Although the majority of adolescents and emerging adults are still religiously involved, twice as many 12th graders and college students, and 20%–40% more 8th and 10th graders, never attend religious services. Twice as many 12th graders and entering college students in the 2010s (vs. the 1960s–70s) give their religious affiliation as “none,” as do 40%–50% more 8th and 10th graders. Recent birth cohorts report less approval of religious organizations, are less likely to say that religion is important in their lives, report being less spiritual, and spend less time praying or meditating. Thus, declines in religious orientation reach beyond affiliation to religious participation and religiosity, suggesting a movement toward secularism among a growing minority. The declines are larger among girls, Whites, lower-SES individuals, and in the Northeastern U.S., very small among Blacks, and non-existent among political conservatives. Religious affiliation is lower in years with more income inequality, higher median family income, higher materialism, more positive self-views, and lower social support. Overall, these results suggest that the lower religious orientation of Millennials is due to time period or generation, and not to age. PMID:25962174

  18. Generational and time period differences in American adolescents' religious orientation, 1966-2014.

    PubMed

    Twenge, Jean M; Exline, Julie J; Grubbs, Joshua B; Sastry, Ramya; Campbell, W Keith

    2015-01-01

    In four large, nationally representative surveys (N = 11.2 million), American adolescents and emerging adults in the 2010s (Millennials) were significantly less religious than previous generations (Boomers, Generation X) at the same age. The data are from the Monitoring the Future studies of 12th graders (1976-2013), 8th and 10th graders (1991-2013), and the American Freshman survey of entering college students (1966-2014). Although the majority of adolescents and emerging adults are still religiously involved, twice as many 12th graders and college students, and 20%-40% more 8th and 10th graders, never attend religious services. Twice as many 12th graders and entering college students in the 2010s (vs. the 1960s-70s) give their religious affiliation as "none," as do 40%-50% more 8th and 10th graders. Recent birth cohorts report less approval of religious organizations, are less likely to say that religion is important in their lives, report being less spiritual, and spend less time praying or meditating. Thus, declines in religious orientation reach beyond affiliation to religious participation and religiosity, suggesting a movement toward secularism among a growing minority. The declines are larger among girls, Whites, lower-SES individuals, and in the Northeastern U.S., very small among Blacks, and non-existent among political conservatives. Religious affiliation is lower in years with more income inequality, higher median family income, higher materialism, more positive self-views, and lower social support. Overall, these results suggest that the lower religious orientation of Millennials is due to time period or generation, and not to age. PMID:25962174

  19. Generational and time period differences in American adolescents' religious orientation, 1966-2014.

    PubMed

    Twenge, Jean M; Exline, Julie J; Grubbs, Joshua B; Sastry, Ramya; Campbell, W Keith

    2015-01-01

    In four large, nationally representative surveys (N = 11.2 million), American adolescents and emerging adults in the 2010s (Millennials) were significantly less religious than previous generations (Boomers, Generation X) at the same age. The data are from the Monitoring the Future studies of 12th graders (1976-2013), 8th and 10th graders (1991-2013), and the American Freshman survey of entering college students (1966-2014). Although the majority of adolescents and emerging adults are still religiously involved, twice as many 12th graders and college students, and 20%-40% more 8th and 10th graders, never attend religious services. Twice as many 12th graders and entering college students in the 2010s (vs. the 1960s-70s) give their religious affiliation as "none," as do 40%-50% more 8th and 10th graders. Recent birth cohorts report less approval of religious organizations, are less likely to say that religion is important in their lives, report being less spiritual, and spend less time praying or meditating. Thus, declines in religious orientation reach beyond affiliation to religious participation and religiosity, suggesting a movement toward secularism among a growing minority. The declines are larger among girls, Whites, lower-SES individuals, and in the Northeastern U.S., very small among Blacks, and non-existent among political conservatives. Religious affiliation is lower in years with more income inequality, higher median family income, higher materialism, more positive self-views, and lower social support. Overall, these results suggest that the lower religious orientation of Millennials is due to time period or generation, and not to age.

  20. Precise timing of the last interglacial period from mass spectrometric determination of thorium-230 in corals

    SciTech Connect

    Edwards, R.L.; Chen, J.H.; Ku, T.L.; Wasserburg, G.J.

    1987-06-19

    The development of mass spectrometric techniques for determination of STTh abundance has made it possible to reduce analytical errors in STYU-STUU-STTh dating of corals even with very small samples. Samples of 6 x 10Y atoms of STTh can be measured to an accuracy of +/- 3% (2sigma) and 3 x 10 atoms of STTh can be measured to an accuracy of +/- 0.2%. The time range over which useful age data on corals can be obtained now ranges from about 50 to about 500,000 years. For young corals, this approach may be preferable to UC dating. The precision should make it possible to critically test the Milankovitch hypothesis concerning Pleistocene climate fluctuations. Analyses of a number of corals that grew during the last interglacial period yield ages of 122,000 to 130,000 years. The ages coincide with, or slightly postdate, the summer solar insolation high at 65N latitude which occurred 128,000 years ago. This supports the idea that changes in Pleistocene climate can be the result of variations in the distribution of solar insolation caused by changes in the geometry of the earth's orbit and rotation axis.

  1. Mars exploration, Venus swingby and conjunction class mission modes, time period 2000 to 2045

    NASA Technical Reports Server (NTRS)

    Young, A. C.; Mulqueen, J. A.; Skinner, J. E.

    1984-01-01

    Trajectory and mission requirement data are presented for Earth-Mars opposition class and conjunction class round trip stopover mission opportunities available during the time period year 2000 to year 2045. The opposition class mission employs the gravitational field of Venus to accelerate the space vehicle on either the outbound or inbound leg. The gravitational field of Venus was used to reduce the propulsion requirement associated with the opposition class mission. Representative space vehicle systems are sized to compare the initial mass required in low Earth orbit of one mission opportunity with another mission opportunity. The interplanetary space vehicle is made up of the spacecraft and the space vehicle acceleration system. The space vehicle acceleration system consists of three propulsion stages. The first propulsion stage performs the Earth escape maneuver; the second stage brakes the spacecraft and Earth braking stage into the Mars elliptical orbit and effects the escape maneuver from the Mars elliptical orbit. The third propulsion stage brakes the mission module into an elliptical orbit at Earth return. The interplanetary space vehicle was assumed to be assembled in and depart from the space station circular orbit.

  2. Precise timing of the last interglacial period from mass spectrometric determination of thorium-230 in corals

    NASA Technical Reports Server (NTRS)

    Chen, J. H.; Wasserburg, G. J.; Ku, T.-L.; Edwards, R. Lawrence

    1987-01-01

    The development of mass spectrometric techniques for determination of Th-230 abundance has made it possible to reduce analytical errors in (U-238)-(U-234)-(Th-230) dating of corals even with very small samples. Samples of 6 x 10 to the 8th atoms of Th-230 can be measured to an accuracy of + or - 3 percent (2sigma), and 3 x 10 to the 10th atoms of Th-230 can be measured to an accuracy of + or - 0.2 percent. The time range over which useful age data on corals can be obtained now ranges from about 50 to about 500,000 years. For young corals, this approach may be preferable to C-14 dating. The precision with which the age of a coral can now be determined should make it possible to critically test the Milankovitch hypothesis concerning Pleistocene climate fluctuations. Analyses of a number of corals that grew during the last interglacial period yield ages of 122,000 to 130,000 years. The ages coincide with, or slightly post-date, the summer solar insolation high at 65 deg N latitude which occurred 128,000 years ago. This supports the idea that changes in Pleistocene climate can be the result of variations in the distribution of solar insolation caused by changes in the geometry of the earth's orbit and rotation axis.

  3. Studies of cortical interactions over short periods of time during the search for verbal associations.

    PubMed

    Nikolaev, A R; Ivanitskii, G A; Ivanitskii, A M

    2001-01-01

    Interactions between cortical areas were studied during the search for verbal associations and reading of words. The functional anatomy and the sequence of involvement of cortical areas during the solution of these tasks have been described previously, in studies using positron emission tomography and multichannel recordings of evoked potentials combined with identification of the locations of dipole sources [8, 9, 19, 25]. Cortical interactions reflected in terms of the synchronization of EEG rhythms were studied by developing a method based on correlating curve wavelets, which allows the moments at which this synchronization occurs to be identified over short periods of time comparable with the speeds of individual thought operations (up to 100 msec). Three main stages were identified in the search for associations. During the first 200 msec after stimulus presentation, cortical connections were seen between the right and left frontal areas; at 200-500 msec, there were connections between the frontal and the temporal-parietal areas; finally, at 450-700 sec, there were connections between the left temporal and the right frontal-central-temporal areas. These results are in good agreement with data obtained previously using other methods and supplement them with mapping data on cortical connections. A number of differences in the mechanisms of information processing during the search for associations and reading were also identified.

  4. Platelet aggregation responses vary over a period of time in healthy controls.

    PubMed

    Refaai, Majed A; Frenkel, Eugene; Sarode, Ravi

    2010-01-01

    Platelet aggregation study is performed to investigate platelet function abnormality. A normal healthy control sample is usually run with the patient sample as a quality control measure. At our institution, we observed variations in platelet aggregation responses in our normal repeat controls. Therefore, we analysed aggregation parameters in these controls. Whole blood aggregation studies were performed with adenosine diphosphate (ADP), arachidonic acid (AA), collagen and ristocetin. Adenosine triphosphate (ATP) secretion was also measured simultaneously by leuciferin-leuciferase reaction. During a 5-year period, a total of 86 studies were performed on seven controls. Aggregations were within the acceptable range in 67% of the time. Collagen was the most affected agonist in our study. On five occasions, four controls had subnormal aggregations with two agonists. All abnormal responses were hypoaggregation except for two who had hyperaggregation with collagen and AA. Only one out of seven controls was always normal. In the presence of a subnormal control result, a new control was run before releasing the patient's platelet aggregation results. These findings suggest that many physiological factors, other than medications, may affect platelet function even in normal individuals. Therefore, a repeat study at a later date to demonstrate a reproducible abnormality would be prudent before labeling a patient's platelets abnormal.

  5. A simple derivation for amplitude and time period of charged particles in an electrostatic bathtub potential

    NASA Astrophysics Data System (ADS)

    Prathap Reddy, K.

    2016-11-01

    An ‘electrostatic bathtub potential’ is defined and analytical expressions for the time period and amplitude of charged particles in this potential are obtained and compared with simulations. These kinds of potentials are encountered in linear electrostatic ion traps, where the potential along the axis appears like a bathtub. Ion traps are used in basic physics research and mass spectrometry to store ions; these stored ions make oscillatory motion within the confined volume of the trap. Usually these traps are designed and studied using ion optical software, but in this work the bathtub potential is reproduced by making two simple modifications to the harmonic oscillator potential. The addition of a linear ‘k 1|x|’ potential makes the simple harmonic potential curve steeper with a sharper turn at the origin, while the introduction of a finite-length zero potential region at the centre reproduces the flat region of the bathtub curve. This whole exercise of modelling a practical experimental situation in terms of a well-known simple physics problem may generate interest among readers.

  6. It's T time: A study on the return period of multivariate problems

    NASA Astrophysics Data System (ADS)

    Michailidi, Eleni Maria; Balistrocchi, Matteo; Bacchi, Baldassare

    2016-04-01

    One of the most important tasks a hydrologist must face is the proper estimation of the 'design values' of a natural variable corresponding to a given Return Period, T, of failures of the hydraulic 'structure' to be designed or verified. Sometimes the 'structure' is simply the embankments, the failure of which corresponds to the outflows of flood runoff on the surrounding land. The widely adopted definition of T, in a problem regarding the maxima of hydrological variables, is "the average time elapsing between two successive occurrences of an event exceeding a certain magnitude of the natural variables". If T is referred to the minima, the symmetric definition pertains to the "average time between two periods during which the variable ranges below a given magnitude". Conventional (and the only accepted) approaches for estimation of T involve a single natural variable (i.e. flood-peak of a river at a given cross section, the daily maximum discharge, the maximum daily rainfall depth observed at a given rain-gauge). The method of estimation of T entails a frequency analysis of the variable of interest, where the design value of a given T is needed to design the structure of interest (e.g. dams, sewers). In other words, T is used as the index value to set the assigned risk level for the hydraulic works. However, a univariate approach in complex problems ignores the effect of significant variables interrelation leading to different risk levels for each quantity of interest and resulting in a completely wrong estimate of the risk. For example, if one considers the flood inflow in a lake around which cities and villages are positioned, the variable to be investigated in relation to the risk assessment is the lake water level. It is obvious that the same water level may occur from very different flood hydrographs, even when the same initial water level and the same rate curve of outflows are considered. This is a consequence of the interaction of at least three joint

  7. Treatment of a Circadian Rhythm Disturbance in a 2-Year-Old Blind Child.

    ERIC Educational Resources Information Center

    Mindell, J. A.; And Others

    1996-01-01

    The use of sleep scheduling and a daytime routine for the treatment of circadian rhythm disorder was found helpful in decreasing a blind 2-year old's nighttime wake periods and daytime sleepiness. (DB)

  8. Motor recovery after stroke depends on intact sustained attention: a 2-year follow-up study.

    PubMed

    Robertson, I H; Ridgeway, V; Greenfield, E; Parr, A

    1997-04-01

    The functional recovery of 47 right-brain-damaged stroke patients was studied over a 2-year period. The researchers hypothesized that sustained attention capacity should predict the degree of motor and functional recovery over this period because of a proposed privileged role of sustained attention in learning-based recovery of function. As predicted, significant correlations were found between sustained attention capacity at 2 months and functional status (including the Barthel Index) at 2 years. This relationship was shown to exist independently of 2-month functional status. Furthermore, compared with a left-brain-damaged group of cerebrovascular accident (CVA) patients, the right-brain CVA group did not recover functional ability as well over the 2-year period. This increasing difference in functional status over a 2-year period was mirrored by an emerging difference in sustained attention capacity, in favor of the left-brain CVA group.

  9. Survival of Bacillus pumilus spores for a prolonged period of time in real space conditions.

    PubMed

    Vaishampayan, Parag A; Rabbow, Elke; Horneck, Gerda; Venkateswaran, Kasthuri J

    2012-05-01

    To prevent forward contamination and maintain the scientific integrity of future life-detection missions, it is important to characterize and attempt to eliminate terrestrial microorganisms associated with exploratory spacecraft and landing vehicles. Among the organisms isolated from spacecraft-associated surfaces, spores of Bacillus pumilus SAFR-032 exhibited unusually high resistance to decontamination techniques such as UV radiation and peroxide treatment. Subsequently, B. pumilus SAFR-032 was flown to the International Space Station (ISS) and exposed to a variety of space conditions via the European Technology Exposure Facility (EuTEF). After 18 months of exposure in the EXPOSE facility of the European Space Agency (ESA) on EuTEF under dark space conditions, SAFR-032 spores showed 10-40% survivability, whereas a survival rate of 85-100% was observed when these spores were kept aboard the ISS under dark simulated martian atmospheric conditions. In contrast, when UV (>110 nm) was applied on SAFR-032 spores for the same time period and under the same conditions used in EXPOSE, a ∼7-log reduction in viability was observed. A parallel experiment was conducted on Earth with identical samples under simulated space conditions. Spores exposed to ground simulations showed less of a reduction in viability when compared with the "real space" exposed spores (∼3-log reduction in viability for "UV-Mars," and ∼4-log reduction in viability for "UV-Space"). A comparative proteomics analysis indicated that proteins conferring resistant traits (superoxide dismutase) were present in higher concentration in space-exposed spores when compared to controls. Also, the first-generation cells and spores derived from space-exposed samples exhibited elevated UVC resistance when compared with their ground control counterparts. The data generated are important for calculating the probability and mechanisms of microbial survival in space conditions and assessing microbial contaminants

  10. Magnetic cycles and rotation periods of late-type stars from photometric time series

    NASA Astrophysics Data System (ADS)

    Suárez Mascareño, A.; Rebolo, R.; González Hernández, J. I.

    2016-10-01

    Aims: We investigate the photometric modulation induced by magnetic activity cycles and study the relationship between rotation period and activity cycle(s) in late-type (FGKM) stars. Methods: We analysed light curves, spanning up to nine years, of 125 nearby stars provided by the All Sky Automated Survey (ASAS). The sample is mainly composed of low-activity, main-sequence late-A to mid-M-type stars. We performed a search for short (days) and long-term (years) periodic variations in the photometry. We modelled the light curves with combinations of sinusoids to measure the properties of these periodic signals. To provide a better statistical interpretation of our results, we complement our new results with results from previous similar works. Results: We have been able to measure long-term photometric cycles of 47 stars, out of which 39 have been derived with false alarm probabilities (FAP) of less than 0.1 per cent. Rotational modulation was also detected and rotational periods were measured in 36 stars. For 28 stars we have simultaneous measurements of activity cycles and rotational periods, 17 of which are M-type stars. We measured both photometric amplitudes and periods from sinusoidal fits. The measured cycle periods range from 2 to 14 yr with photometric amplitudes in the range of 5-20 mmag. We found that the distribution of cycle lengths for the different spectral types is similar, as the mean cycle is 9.5 yr for F-type stars, 6.7 yr for G-type stars, 8.5 yr for K-type stars, 6.0 yr for early M-type stars, and 7.1 yr for mid-M-type stars. On the other hand, the distribution of rotation periods is completely different, trending to longer periods for later type stars, from a mean rotation of 8.6 days for F-type stars to 85.4 days in mid-M-type stars. The amplitudes induced by magnetic cycles and rotation show a clear correlation. A trend of photometric amplitudes with rotation period is also outlined in the data. The amplitudes of the photometric variability

  11. Timing analysis of the periodic radio and optical brightness variations of the ultracool dwarf, TVLM 513-46546

    SciTech Connect

    Wolszczan, A.; Route, M. E-mail: matthew.route@ngc.com

    2014-06-10

    We describe the arrival time measurements and timing modeling of the periodic radio flares and optical brightness variations of the M9 ultracool dwarf, TVLM 513-46546. We confirm the stability of the observed period and determine its best-fit value to be 7054.468 ± 0.007 s over the last 7 yr, based on both the new and archival radio observations and the archival optical data. The period, when measured separately for the radio flare and the optical periodicities, is the same to within ±0.02 s. We show that the radio flares are out of phase with respect to the optical brightness maxima by 0.41 ± 0.02 of the period. Our analysis also reveals that, on shorter timescales, the period varies with the amplitude of ±1-2 s about its long-term average and that these variations are correlated between the radio and the optical wavelengths. These results provide further evidence that TVLM 513-46546 is equipped with a stable, approximately dipolar magnetic field that powers the activity of the star observed over a wide wavelength range, and that the active area has been maintaining its identity and positional stability over no less than 7 yr. A stepwise decline of the apparent radio flaring period of TVLM 513-46546, deduced from timing observations with the Arecibo radio telescope in late 2012 and early 2013, suggests that this effect may be the manifestation of differential rotation of the star.

  12. 41 CFR 302-11.23 - When must I request to have my initial time period extended?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... have my initial time period extended? 302-11.23 Section 302-11.23 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time...

  13. 41 CFR 302-11.23 - When must I request to have my initial time period extended?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... have my initial time period extended? 302-11.23 Section 302-11.23 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time...

  14. 41 CFR 302-11.23 - When must I request to have my initial time period extended?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... have my initial time period extended? 302-11.23 Section 302-11.23 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time...

  15. 41 CFR 302-11.23 - When must I request to have my initial time period extended?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... have my initial time period extended? 302-11.23 Section 302-11.23 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time...

  16. 41 CFR 302-11.23 - When must I request to have my initial time period extended?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... have my initial time period extended? 302-11.23 Section 302-11.23 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RESIDENCE TRANSACTION ALLOWANCES 11-ALLOWANCES FOR EXPENSES INCURRED IN CONNECTION WITH RESIDENCE TRANSACTIONS General Rules Time...

  17. [Local fractal analysis of noise-like time series by all permutations method for 1-115 min periods].

    PubMed

    Panchelyuga, V A; Panchelyuga, M S

    2015-01-01

    Results of local fractal analysis of 329-per-day time series of 239Pu alpha-decay rate fluctuations by means of all permutations method (APM) are presented. The APM-analysis reveals in the time series some steady frequency set. The coincidence of the frequency set with the Earth natural oscillations was demonstrated. A short review of works by different authors who analyzed the time series of fluctuations in processes of different nature is given. We have shown that the periods observed in those works correspond to the periods revealed in our study. It points to a common mechanism of the phenomenon observed. PMID:26016038

  18. [Local fractal analysis of noise-like time series by all permutations method for 1-115 min periods].

    PubMed

    Panchelyuga, V A; Panchelyuga, M S

    2015-01-01

    Results of local fractal analysis of 329-per-day time series of 239Pu alpha-decay rate fluctuations by means of all permutations method (APM) are presented. The APM-analysis reveals in the time series some steady frequency set. The coincidence of the frequency set with the Earth natural oscillations was demonstrated. A short review of works by different authors who analyzed the time series of fluctuations in processes of different nature is given. We have shown that the periods observed in those works correspond to the periods revealed in our study. It points to a common mechanism of the phenomenon observed.

  19. Assessment of high-rate GPS time series at long periods

    NASA Astrophysics Data System (ADS)

    Kelevitz, Krisztina; Houlié, Nicolas; Boschi, Lapo; Nissen-Meyer, Tarje; Giardini, Domenico; Rothacher, Markus

    2015-04-01

    High-rate GPS has been proven to be sensitive to ground motions that are induced by surface waves from large earthquakes even hundreds kilometers from the epicenter (Larson et al. (2003a)). Since the broadband seismometers are less sensitive to the long period surface waves (T > 300 seconds), the seismic velocity tomography models start to diverge for depths larger than 400 km (Becker and Boschi (2002); Ritsema et al. (2011)). Because of their good accuracy at long-periods (detecting ground displacements above 2 mm), GPS measurements could be used to support broadband seismometer networks (Houliè et al. (2011); Bilich et al. (2008)) and strong motion networks in near field (Houliè et al. (2014)) by providing high-quality waveforms in displacement for periods T > 3s. We present the comparison of 1Hz high-rate GPS data, very broadband seismograms and super-conductivity gravimeter data for various period bands (T > 30 s) using the observations collected during three mega-thrust events: 2003 Hokkaido, 2004 Sumatra and 2011 Tohoku-Oki. We assess the performance of each dataset at the light of comparison with synthetic waveforms that were computed using the AXISEM and SPECFEM algorithms. With this study we aim at filling the gap between the surface wave (T < 60 seconds) and normal mode (T 1200 seconds) period ranges. We find that GPS is well capable on recovering millimeter ground motion oscillations in a wide range of periods, providing valuable information on the lithosphere and mantle heterogeneities on a scale of 300 to 3000 km.

  20. What is the Most Suitable Time Period to Assess the Time Trends in Cancer Incidence Rates to Make Valid Predictions--an Empirical Approach.

    PubMed

    Ramnath, Takiar; Shah, Varsha Premchandbhai; Krishnan, Sathish Kumar

    2015-01-01

    Projections of cancer cases are particularly useful in developing countries to plan and prioritize both diagnostic and treatment facilities. In the prediction of cancer cases for the future period say after 5 years or after 10 years, it is imperative to use the knowledge of past time trends in incidence rates as well as in population at risk. In most of the recently published studies the duration for which the time trend was assessed was more than 10 years while in few studies the duration was between 5-7 years. This raises the question as to what is the optimum time period which should be used for assessment of time trends and projections. Thus, the present paper explores the suitability of different time periods to predict the future rates so that the valid projections of cancer burden can be done for India. The cancer incidence data of selected cancer sites of Bangalore, Bhopal, Chennai, Delhi and Mumbai PBCR for the period of 1991-2009 was utilized. The three time periods were selected namely 1991-2005; 1996-2005, 1999-2005 to assess the time trends and projections. For the five selected sites, each for males and females and for each registry, the time trend was assessed and the linear regression equation was obtained to give prediction for the years 2006, 2007, 2008 and 2009. These predictions were compared with actual incidence data. The time period giving the least error in prediction was adjudged as the best. The result of the current analysis suggested that for projections of cancer cases, the 10 years duration data are most appropriate as compared to 7 year or 15 year incidence data. PMID:25921103

  1. 29 CFR 4000.43 - How do I compute a time period?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... holidays. However, if the last day you count is a weekend or Federal holiday, extend or shorten the period..., together with the weekend and holiday rule of paragraph (a) of this section. (c) When counting months. If a... on a weekend or Federal holiday, follow the weekend and holiday rule of paragraph (a) of this...

  2. 29 CFR 4000.43 - How do I compute a time period?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... holidays. However, if the last day you count is a weekend or Federal holiday, extend or shorten the period..., together with the weekend and holiday rule of paragraph (a) of this section. (c) When counting months. If a... on a weekend or Federal holiday, follow the weekend and holiday rule of paragraph (a) of this...

  3. 18 CFR 290.103 - Time of filing and reporting period.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... reporting period. 290.103 Section 290.103 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY REGULATORY POLICIES ACT OF... preceding the filing year. Information for previous years and projected information for future years must...

  4. 18 CFR 290.103 - Time of filing and reporting period.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... reporting period. 290.103 Section 290.103 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY REGULATORY POLICIES ACT OF... preceding the filing year. Information for previous years and projected information for future years must...

  5. Clinical neuroprediction: Amygdala reactivity predicts depressive symptoms 2 years later.

    PubMed

    Mattson, Whitney I; Hyde, Luke W; Shaw, Daniel S; Forbes, Erika E; Monk, Christopher S

    2016-06-01

    Depression is linked to increased amygdala activation to neutral and negatively valenced facial expressions. Amygdala activation may be predictive of changes in depressive symptoms over time. However, most studies in this area have focused on small, predominantly female and homogenous clinical samples. Studies are needed to examine how amygdala reactivity relates to the course of depressive symptoms dimensionally, prospectively and in populations diverse in gender, race and socioeconomic status. A total of 156 men from predominately low-income backgrounds completed an fMRI task where they viewed emotional facial expressions. Left and right amygdala reactivity to neutral, but not angry or fearful, facial expressions relative to a non-face baseline at age 20 predicted greater depressive symptoms 2 years later, controlling for age 20 depressive symptoms. Heightened bilateral amygdala reactivity to neutral facial expressions predicted increases in depressive symptoms 2 years later in a large community sample. Neutral facial expressions are affectively ambiguous and a tendency to interpret these stimuli negatively may reflect to cognitive biases that lead to increases in depressive symptoms over time. Individual differences in amygdala reactivity to neutral facial expressions appear to identify those at most risk for a more problematic course of depressive symptoms across time. PMID:26865423

  6. Diffusive KPP equations with free boundaries in time almost periodic environments: II. Spreading speeds and semi-wave solutions

    NASA Astrophysics Data System (ADS)

    Li, Fang; Liang, Xing; Shen, Wenxian

    2016-08-01

    In this series of papers, we investigate the spreading and vanishing dynamics of time almost periodic diffusive KPP equations with free boundaries. Such equations are used to characterize the spreading of a new species in time almost periodic environments with free boundaries representing the spreading fronts. In the first part of the series, we showed that a spreading-vanishing dichotomy occurs for such free boundary problems (see [16]). In this second part of the series, we investigate the spreading speeds of such free boundary problems in the case that the spreading occurs. We first prove the existence of a unique time almost periodic semi-wave solution associated to such a free boundary problem. Using the semi-wave solution, we then prove that the free boundary problem has a unique spreading speed.

  7. Age-Period-Cohort Models in Cancer Surveillance Research: Ready for Prime Time?

    PubMed Central

    Rosenberg, Philip S.; Anderson, William F.

    2011-01-01

    Standard descriptive methods for the analysis of cancer surveillance data include canonical plots based on the lexis diagram, directly age-standardized rates (ASR), estimated annual percentage change (EAPC), and joinpoint regression. The age-period-cohort (APC) model has been used less often. Here, we argue that it merits much broader use. Firstly, we describe close connections between estimable functions of the model parameters and standard quantities such as the ASR, EAPC, and joinpoints. Estimable functions have the added value of being fully adjusted for period and cohort effects, and generally more precise. Secondly, the APC model provides the descriptive epidemiologist with powerful new tools, including rigorous statistical methods for comparative analyses and the ability to project the future burden of cancer. We illustrate these principles using invasive female breast cancer incidence in the United States, but these concepts apply equally well to other cancer sites for incidence or mortality. PMID:21610223

  8. A charged particle in a homogeneous magnetic field accelerated by a time-periodic Aharonov-Bohm flux

    SciTech Connect

    Kalvoda, T.; Stovicek, P.

    2011-10-15

    We consider a nonrelativistic quantum charged particle moving on a plane under the influence of a uniform magnetic field and driven by a periodically time-dependent Aharonov-Bohm flux. We observe an acceleration effect in the case when the Aharonov-Bohm flux depends on time as a sinusoidal function whose frequency is in resonance with the cyclotron frequency. In particular, the energy of the particle increases linearly for large times. An explicit formula for the acceleration rate is derived with the aid of the quantum averaging method, and then it is checked against a numerical solution and a very good agreement is found. - Highlights: > A nonrelativistic quantum charged particle on a plane. > A homogeneous magnetic field and a periodically time-dependent Aharonov-Bohm flux. > The quantum averaging method applied to a time-dependent system. > A resonance of the AB flux with the cyclotron frequency. > An acceleration with linearly increasing energy; a formula for the acceleration rate.

  9. Clustering criterion for inertial particles in two-dimensional time-periodic and three-dimensional steady flows.

    PubMed

    Sapsis, Themistoklis; Haller, George

    2010-03-01

    We derive an analytic condition that predicts the exact location of inertial particle clustering in three-dimensional steady or two-dimensional time-periodic flows. The particles turn out to cluster on attracting inertial Lagrangian coherent structures that are smooth deformations of invariant tori. We illustrate our results on three-dimensional steady flows, including the Hill's spherical vortex and the Arnold-Beltrami-Childress flow, as well as on a two-dimensional time and space periodic flow that models a meandering jet in a channel.

  10. The time-periodic diffusive competition models with a free boundary and sign-changing growth rates

    NASA Astrophysics Data System (ADS)

    Wang, Mingxin; Zhang, Yang

    2016-10-01

    To understand the spreading of invasive and native species, in this paper we consider the diffusive competition models with a free boundary in the heterogeneous time-periodic environments, in which the variable intrinsic growth rates of these two species change signs and may be very negative in some large regions. We study the spreading-vanishing dichotomy, long-time dynamical behavior of solution, sharp criteria for spreading and vanishing, and estimates of the asymptotic spreading speed of the free boundary. Moreover, we establish the existence of positive solutions to a T-periodic boundary value problem of the diffusive competition system with sign-changing growth rates in the half line.

  11. A functional asymmetry in the Leech Heartbeat Timing Network is revealed by driving the network across various cycle periods.

    PubMed

    Masino, Mark A; Calabrese, Ronald L

    2002-06-01

    We tested predictions of a computational model (Hill et al., 2002) of the leech heartbeat timing network. The timing network consists of two segmental oscillators located in the third (G3) and fourth (G4) segmental ganglia. Each oscillator consists of two reciprocally inhibitory oscillator interneurons along with the coordinating interneuron fibers that link them. In the model, the network was driven to cycle periods around the normal period of the network by repeatedly stimulating one of the paired oscillator interneurons in G3 or G4. Here we replicate these experiments in the biological system. The model predicts that the G3 and G4 oscillators can entrain the timing network to periods faster but not slower than the inherent period of the nondriven ("follower") oscillator and that they can do so symmetrically. The biological system can be driven to periods both faster (such that the driven oscillator leads in phase) and slower (such that the driven oscillator lags in phase) than the inherent period of the timing network. Although both oscillators can entrain the network, the G4 oscillator does so over a narrower range of periods. Two differences between the assumptions of the model and the properties of the biological network, spike frequency adaptation in coordinating interneurons and asymmetry in the connections from the oscillator interneurons to the coordinating interneurons, may account for these discrepancies. Individual coordinating interneurons were also able to entrain the oscillators but with little effect of the phase relationship between the oscillators, suggesting that phase relations are determined by properties inherent to the oscillator interneurons.

  12. A mapping method for distributive mixing with diffusion: Interplay between chaos and diffusion in time-periodic sine flow

    NASA Astrophysics Data System (ADS)

    Schlick, Conor P.; Christov, Ivan C.; Umbanhowar, Paul B.; Ottino, Julio M.; Lueptow, Richard M.

    2013-05-01

    We present an accurate and efficient computational method for solving the advection-diffusion equation in time-periodic chaotic flows. The method uses operator splitting, which allows the advection and diffusion steps to be treated independently. Taking advantage of flow periodicity, the advection step is solved using a mapping method, and diffusion is "added" discretely after each iteration of the advection map. This approach results in the construction of a composite mapping matrix over an entire period of the chaotic advection-diffusion process and provides a natural framework for the analysis of mixing. To test the approach, we consider two-dimensional time-periodic sine flow. By comparing the numerical solutions obtained by our method to reference solutions, we find qualitative agreement for large time steps (structure of concentration profile) and quantitative agreement for small time steps (low error). Further, we study the interplay between mixing through chaotic advection and mixing through diffusion leading to an analytical model for the evolution of the intensity of segregation with time. Additionally, we demonstrate that our operator splitting mapping approach can be readily extended to three dimensions.

  13. Framing Health Messages for Adolescents: Should We Use Objective Time Periods, Temporal Benchmarks, or Both?

    ERIC Educational Resources Information Center

    McKay, Michael T.; Cole, Jon C.; Sumnall, Harry R.; Goudie, Andrew J.

    2012-01-01

    Time perspective is a cognitive-motivational construct, which has been shown to be related to decision-making, motivation and adjustment. The majority of research into time perspective has been conducted in college students and/or general population samples. Focus groups were held as part of a larger investigation into the relationship between…

  14. Bats and frogs and animals in between: evidence for a common central timing mechanism to extract periodicity pitch

    PubMed Central

    Simmons, James A.; Simmons, Andrea Megela

    2012-01-01

    Widely divergent vertebrates share a common central temporal mechanism for representing periodicities of acoustic waveform events. In the auditory nerve, periodicities corresponding to frequencies or rates from about 10 Hz to over 1,000 Hz are extracted from pure tones, from low-frequency complex sounds (e.g., 1st harmonic in bullfrog calls), from mid-frequency sounds with low-frequency modulations (e.g., amplitude modulation rates in cat vocalizations), and from time intervals between high-frequency transients (e.g., pulse-echo delay in bat sonar). Time locking of neuronal responses to periodicities from about 50 ms down to 4 ms or less (about 20–300 Hz) is preserved in the auditory midbrain, where responses are dispersed across many neurons with different onset latencies from 4–5 to 20–50 ms. Midbrain latency distributions are wide enough to encompass two or more repetitions of successive acoustic events, so that responses to multiple, successive periods are ongoing simultaneously in different midbrain neurons. These latencies have a previously unnoticed periodic temporal pattern that determines the specific times for the dispersed on-responses. PMID:21072522

  15. Bats and frogs and animals in between: evidence for a common central timing mechanism to extract periodicity pitch.

    PubMed

    Simmons, James A; Megela Simmons, Andrea

    2011-05-01

    Widely divergent vertebrates share a common central temporal mechanism for representing periodicities of acoustic waveform events. In the auditory nerve, periodicities corresponding to frequencies or rates from about 10 Hz to over 1,000 Hz are extracted from pure tones, from low-frequency complex sounds (e.g., 1st harmonic in bullfrog calls), from mid-frequency sounds with low-frequency modulations (e.g., amplitude modulation rates in cat vocalizations), and from time intervals between high-frequency transients (e.g., pulse-echo delay in bat sonar). Time locking of neuronal responses to periodicities from about 50 ms down to 4 ms or less (about 20-300 Hz) is preserved in the auditory midbrain, where responses are dispersed across many neurons with different onset latencies from 4-5 to 20-50 ms. Midbrain latency distributions are wide enough to encompass two or more repetitions of successive acoustic events, so that responses to multiple, successive periods are ongoing simultaneously in different midbrain neurons. These latencies have a previously unnoticed periodic temporal pattern that determines the specific times for the dispersed on-responses.

  16. Space Radiation Cancer Risks and Uncertainities for Different Mission Time Periods

    NASA Technical Reports Server (NTRS)

    Kim,Myung-Hee Y.; Cucinotta, Francis A.

    2012-01-01

    Space radiation consists of solar particle events (SPEs), comprised largely of medium energy protons (less than several hundred MeV); and galactic cosmic ray (GCR), which includes high energy protons and high charge and energy (HZE) nuclei. For long duration missions, space radiation presents significant health risks including cancer mortality. Probabilistic risk assessment (PRA) is essential for radiation protection of crews on long term space missions outside of the protection of the Earth s magnetic field and for optimization of mission planning and costs. For the assessment of organ dosimetric quantities and cancer risks, the particle spectra at each critical body organs must be characterized. In implementing a PRA approach, a statistical model of SPE fluence was developed, because the individual SPE occurrences themselves are random in nature while the frequency distribution of SPEs depends strongly upon the phase within the solar activity cycle. Spectral variability of SPEs was also examined, because the detailed energy spectra of protons are important especially at high energy levels for assessing the cancer risk associated with energetic particles for large events. An overall cumulative probability of a GCR environment for a specified mission period was estimated for the temporal characterization of the GCR environment represented by the deceleration potential (theta). Finally, this probabilistic approach to space radiation cancer risk was coupled with a model of the radiobiological factors and uncertainties in projecting cancer risks. Probabilities of fatal cancer risk and 95% confidence intervals will be reported for various periods of space missions.

  17. 18 CFR 290.103 - Time of filing and reporting period.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 1978 COLLECTION OF COST OF SERVICE INFORMATION UNDER SECTION 133 OF THE PUBLIC UTILITY REGULATORY POLICIES ACT OF 1978 Coverage, Compliance and Definitions § 290.103 Time of filing and reporting...

  18. High time-bandwidth product and high repetition rate period signal generation based on spectral hole burning crystal.

    PubMed

    Ma, Xiurong; Wang, Song; Liang, Yuqing; Shan, Yunlong

    2015-04-01

    This paper proposes an approach for the generation of high time-bandwidth product (TBP) and high repetition rate pulse compression period signal. The complex spectral grating is created through a reference pulse and multiple programming pulses with different start frequencies. As the multiple probe chirped pulses with different start frequencies interact with the complex spectral gratings, a high TBP and repetition rate period signal is thus generated. This technique has the potential to generate a time-bandwidth product of 10⁵ when the repetition rate reaches up to tens of GHz. At the end of this paper, two simulation results of pulse compression period signal with 4×10⁵ TBP and 20 GHz repetition rate are presented.

  19. Detecting unstable periodic orbits in high-dimensional chaotic systems from time series: reconstruction meeting with adaptation.

    PubMed

    Ma, Huanfei; Lin, Wei; Lai, Ying-Cheng

    2013-05-01

    Detecting unstable periodic orbits (UPOs) in chaotic systems based solely on time series is a fundamental but extremely challenging problem in nonlinear dynamics. Previous approaches were applicable but mostly for low-dimensional chaotic systems. We develop a framework, integrating approximation theory of neural networks and adaptive synchronization, to address the problem of time-series-based detection of UPOs in high-dimensional chaotic systems. An example of finding UPOs from the classic Mackey-Glass equation is presented.

  20. 41 CFR 302-8.108 - What is the authorized time period for extended storage of my HHG?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What is the authorized time period for extended storage of my HHG? 302-8.108 Section 302-8.108 Public Contracts and Property...-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment to...

  1. 41 CFR 302-8.108 - What is the authorized time period for extended storage of my HHG?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What is the authorized time period for extended storage of my HHG? 302-8.108 Section 302-8.108 Public Contracts and Property...-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment to...

  2. 20 CFR 404.368 - When you are considered a full-time student during a period of nonattendance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false When you are considered a full-time student during a period of nonattendance. 404.368 Section 404.368 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents'...

  3. 20 CFR 404.368 - When you are considered a full-time student during a period of nonattendance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false When you are considered a full-time student during a period of nonattendance. 404.368 Section 404.368 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents'...

  4. 41 CFR 302-8.203 - What is the authorized time period for extended storage of my HHG?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... time period for extended storage of my HHG? 302-8.203 Section 302-8.203 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 8-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment Outside...

  5. 41 CFR 302-8.203 - What is the authorized time period for extended storage of my HHG?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... time period for extended storage of my HHG? 302-8.203 Section 302-8.203 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 8-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment Outside...

  6. 41 CFR 302-8.203 - What is the authorized time period for extended storage of my HHG?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... time period for extended storage of my HHG? 302-8.203 Section 302-8.203 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 8-ALLOWANCES FOR EXTENDED STORAGE OF HOUSEHOLD GOODS (HHG) Extended Storage During Assignment Outside...

  7. 20 CFR 663.530 - Is there a time limit on the period of initial eligibility for training providers?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Is there a time limit on the period of initial eligibility for training providers? 663.530 Section 663.530 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) ADULT AND DISLOCATED WORKER ACTIVITIES UNDER...

  8. 30 CFR 250.1161 - When may I flare or vent gas for extended periods of time?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may I flare or vent gas for extended... Production Requirements Flaring, Venting, and Burning Hydrocarbons § 250.1161 When may I flare or vent gas... flare or vent gas for an extended period of time. The Regional Supervisor will specify the...

  9. 30 CFR 250.1161 - When may I flare or vent gas for extended periods of time?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false When may I flare or vent gas for extended... SHELF Oil and Gas Production Requirements Flaring, Venting, and Burning Hydrocarbons § 250.1161 When may I flare or vent gas for extended periods of time? You must request and receive approval from...

  10. 30 CFR 250.1161 - When may I flare or vent gas for extended periods of time?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false When may I flare or vent gas for extended... SHELF Oil and Gas Production Requirements Flaring, Venting, and Burning Hydrocarbons § 250.1161 When may I flare or vent gas for extended periods of time? You must request and receive approval from...

  11. 30 CFR 250.1161 - When may I flare or vent gas for extended periods of time?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false When may I flare or vent gas for extended... CONTINENTAL SHELF Oil and Gas Production Requirements Flaring, Venting, and Burning Hydrocarbons § 250.1161 When may I flare or vent gas for extended periods of time? You must request and receive approval...

  12. 30 CFR 250.1161 - When may I flare or vent gas for extended periods of time?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false When may I flare or vent gas for extended... SHELF Oil and Gas Production Requirements Flaring, Venting, and Burning Hydrocarbons § 250.1161 When may I flare or vent gas for extended periods of time? You must request and receive approval from...

  13. 20 CFR 404.368 - When you are considered a full-time student during a period of nonattendance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false When you are considered a full-time student during a period of nonattendance. 404.368 Section 404.368 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents'...

  14. 20 CFR 404.368 - When you are considered a full-time student during a period of nonattendance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false When you are considered a full-time student during a period of nonattendance. 404.368 Section 404.368 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents'...

  15. 20 CFR 404.368 - When you are considered a full-time student during a period of nonattendance.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false When you are considered a full-time student during a period of nonattendance. 404.368 Section 404.368 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Old-Age, Disability, Dependents'...

  16. Infantile Amnesia across the Years: A 2-Year Follow-Up of Children's Earliest Memories

    ERIC Educational Resources Information Center

    Peterson, Carole; Warren, Kelly L.; Short, Megan M.

    2011-01-01

    Although infantile amnesia has been investigated for many years in adults, only recently has it been investigated in children. This study was a 2-year follow-up and extension of an earlier study. Children (4-13 years old) were asked initially and 2 years later for their earliest 3 memories. At follow-up, their age at the time of these memories…

  17. Numerical evaluation of the PERTH (PERiodic Tracer Hierarchy) method for estimating time-variable travel time distribution in variably saturated soils

    NASA Astrophysics Data System (ADS)

    Kim, M.; Harman, C. J.

    2013-12-01

    The distribution of water travel times is one of the crucial hydrologic characteristics of the catchment. Recently, it has been argued that a rigorous treatment of travel time distributions should allow for their variability in time because of the variable fluxes and partitioning of water in the water balance, and the consequent variable storage of a catchment. We would like to be able to observe the structure of the temporal variations in travel time distributions under controlled conditions, such as in a soil column or under irrigation experiments. However, time-variable travel time distributions are difficult to observe using typical active and passive tracer approaches. Time-variability implies that tracers introduced at different times will have different travel time distributions. The distribution may also vary during injection periods. Moreover, repeat application of a single tracer in a system with significant memory leads to overprinting of break-through curves, which makes it difficult to extract the original break-through curves, and the number of ideal tracers that can be applied is usually limited. Recognizing these difficulties, the PERTH (PERiodic Tracer Hierarchy) method has been developed. The method provides a way to estimate time-variable travel time distributions by tracer experiments under controlled conditions by employing a multi-tracer hierarchy under periodical hydrologic forcing inputs. The key assumption of the PERTH method is that as time gets sufficiently large relative to injection time, the average travel time distribution of two distinct ideal tracers injected during overlapping periods become approximately equal. Thus one can be used as a proxy for the other, and the breakthrough curves of tracers applied at different times in a periodic forcing condition can be separated from one another. In this study, we tested the PERTH method numerically for the case of infiltration at the plot scale using HYDRUS-1D and a particle

  18. Exenatide once weekly treatment maintained improvements in glycemic control and weight loss over 2 years

    PubMed Central

    2011-01-01

    population. Nausea (predominantly mild in intensity) was the most common adverse event, although the frequency and intensity of nausea decreased over time. No severe hypoglycemia was observed. Conclusions Exenatide QW was well tolerated during the 2-year treatment period. This study demonstrated sustained glucose control and weight loss throughout 2 years of treatment with exenatide QW. Trial Registration ClinicalTrials.gov NCT00308139 PMID:21529363

  19. An investigation of short period oscillations of the solar irradiance and their time variations

    NASA Technical Reports Server (NTRS)

    Noyes, Robert W.

    1987-01-01

    Measurements of solar irradiance fluctuations by the Active Cavity Radiometer (ACRIM) instrument onboard the Solar Maximum Mission (SMM) show variations on a time scale of about 5 minutes due to solar p-mode oscillations, as well as longer-term variations related to solar magnetic activity. The question was studied whether the p-mode frequencies change with time as a result of changing solar structure associated with the activity cycle. The ACRIM data on SMM are particularly well-suited for this purpose, because the instrument operated continuously from February 1980 to December 1980 and again from May 1984 to the present. The main activity entailed a detailed study of the observational data to determine if a change in the p-mode frequencies is evident from the time of solar maximum to that of solar minimum. It was concluded that the measured eigenfrequencies were significantly higher during the 1980 time frame than during the 1984 to 1986 time frame. The conclusion that there is significant change in the eigenfrequencies with the activity cycle remains only tentative, and needs confirmation from analysis of more data during the upcoming solar maximum.

  20. Subjective and objective observation of skin graft recovery on Indonesian local cat with different periods of transplantation time

    PubMed Central

    Erwin; Gunanti; Handharyani, Ekowati; Noviana, Deni

    2016-01-01

    Aim: The success of a skin graft in a cat is highly dependent on the granulation formed by the base of recipient bed. Granulation by the base of recipient bed will form after several days after injury. This research aimed to observe subjective and objective profile of skin graft recovery on forelimb of cats with different periods of donor skin placement. Materials and Methods: Nine male Indonesian local cats aged 1-2 years old, weighing 3-4 kg were divided into three groups. The first surgery for creating defect wound of 2 cm×2 cm in size was performed in the whole group. The wound was left for several days with the respective interval for each group, respectively: Group I (for 2 days), Group II (for 4 days), and Group III (for 6 days). In the whole group, the second surgery was done by the harvesting skin of thoracic area which then applied on recipient bed of respective groups. Result: The donor skin on Group II was accepted faster compared to Group I and Group III. The donor skin did not show color differences compared to surrounding skin, painless, bright red in bleeding test had faster both hair growth and drug absorption. Test toward the size of donor skin and the effect of drugs did not show a significant difference between each group. Conclusion: The observe subjective and objective profile of skin graft recovery on forelimb of cats on Group II were accepted faster compared to Group I and III. PMID:27284224

  1. Lunar periodicity and the timing of river entry in Atlantic salmon Salmo salar.

    PubMed

    Kuparinen, A; O'Hara, R B; Merilä, J

    2009-07-01

    Historical catch records of Atlantic salmon Salmo salar from three rivers discharging to the Baltic Sea in an area free from tides and from strong effects of the moon on illumination were analysed to investigate whether timing of S. salar river entry was associated with lunar cycles directly. Although a significant effect of lunar phase on river entry was detected, with more fish entering rivers around the full moon than other phases, the effect of the lunar cycle was very small compared with other sources of variation. Hence, the biological role of lunar cycle as a determinant of the timing of S. salar runs in the investigated populations was negligible, suggesting that lunar cycle per se does not play a role in the timing of S. salar river entry.

  2. 37 CFR 1.135 - Abandonment for failure to reply within time period.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Abandonment for failure to... Processing Provisions Time for Reply by Applicant; Abandonment of Application § 1.135 Abandonment for failure... action indicates otherwise. (b) Prosecution of an application to save it from abandonment pursuant...

  3. 37 CFR 1.135 - Abandonment for failure to reply within time period.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Abandonment for failure to... Processing Provisions Time for Reply by Applicant; Abandonment of Application § 1.135 Abandonment for failure... action indicates otherwise. (b) Prosecution of an application to save it from abandonment pursuant...

  4. 37 CFR 1.135 - Abandonment for failure to reply within time period.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Abandonment for failure to... Processing Provisions Time for Reply by Applicant; Abandonment of Application § 1.135 Abandonment for failure... action indicates otherwise. (b) Prosecution of an application to save it from abandonment pursuant...

  5. 37 CFR 1.135 - Abandonment for failure to reply within time period.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Abandonment for failure to... Processing Provisions Time for Reply by Applicant; Abandonment of Application § 1.135 Abandonment for failure... action indicates otherwise. (b) Prosecution of an application to save it from abandonment pursuant...

  6. 37 CFR 1.135 - Abandonment for failure to reply within time period.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Abandonment for failure to... Processing Provisions Time for Reply by Applicant; Abandonment of Application § 1.135 Abandonment for failure... action indicates otherwise. (b) Prosecution of an application to save it from abandonment pursuant...

  7. Men's career development and marriage timing during a period of rising inequality.

    PubMed

    Oppenheimer, V K; Kalmijn, M; Lim, N

    1997-08-01

    Based on data from 1979-1990 NLSY interviews, we investigate the implications of rising economic inequality for young men's marriage timing. Our approach is to relate marriage formation to the ease or difficulty of the career-entry process and to show that large race/schooling differences in career development lead to substantial variations in marriage timing. We develop measures of current career "maturity" and of long-term labor-market position. Employing discrete-time event-history methods, we show that these variables have a substantial impact on marriage formation for both blacks and whites. Applying our regression results to models based on observed race/schooling patterns of career development, we then estimate cumulative proportions ever married in a difficult versus an easy career-entry process. We find major differences in the pace of marriage formation, depending on the difficulty of the career transition. We also find considerable differences in these marriage timing patterns across race/schooling groups corresponding to the large observed differences in the speed and difficulty of career transition between and within these groups. PMID:9275242

  8. A procedure of multiple period searching in unequally spaced time-series with the Lomb-Scargle method

    NASA Technical Reports Server (NTRS)

    Van Dongen, H. P.; Olofsen, E.; VanHartevelt, J. H.; Kruyt, E. W.; Dinges, D. F. (Principal Investigator)

    1999-01-01

    Periodogram analysis of unequally spaced time-series, as part of many biological rhythm investigations, is complicated. The mathematical framework is scattered over the literature, and the interpretation of results is often debatable. In this paper, we show that the Lomb-Scargle method is the appropriate tool for periodogram analysis of unequally spaced data. A unique procedure of multiple period searching is derived, facilitating the assessment of the various rhythms that may be present in a time-series. All relevant mathematical and statistical aspects are considered in detail, and much attention is given to the correct interpretation of results. The use of the procedure is illustrated by examples, and problems that may be encountered are discussed. It is argued that, when following the procedure of multiple period searching, we can even benefit from the unequal spacing of a time-series in biological rhythm research.

  9. Analysis of log-periodic power law singularity patterns in time series related to credit risk

    NASA Astrophysics Data System (ADS)

    Wosnitza, Jan Henrik; Sornette, Didier

    2015-04-01

    The log-periodic (super-exponential) power law singularity (LPPLS) has become a promising tool for predicting extreme behavior of self-organizing systems in natural sciences and finance. Some researchers have recently proposed to employ the LPPLS on credit risk markets. The review article at hand summarizes four papers in this field and shows how they are linked. After structuring the research questions, we collect the corresponding answers from the four articles. This eventually gives us an overall picture of the application of the LPPLS to credit risk data. Our literature review begins with grounding the view that credit default swap (CDS) spreads are hotbeds for LPPLS patterns and it ends up with drawing attention to the recently proposed alarm index for the prediction of institutional bank runs. By presenting a new field of application for the LPPLS, the reviewed strand of literature further substantiates the LPPLS hypothesis. Moreover, the results suggest that CDS spread trajectories belong to a different universality class than, for instance, stock prices.

  10. Predominant periods in the time series of drought area index for the Western High Plains AD 1700 to 1962

    NASA Technical Reports Server (NTRS)

    Bell, P. R.

    1981-01-01

    The detection of the combined presence of the Hale magnetic sunspot cycle (22.28 years) and the lunar nodal tidal cycle (18.61 years) in both the Eastern North American January air temperatures and the Western U.S. High Plains drought series led to an extended analysis of the Drought Area Index time series. This analysis indicated that the mean dominant period of the drought series should be 20.0 to 20.5 years and that the principal period should be resolvable into two components of about 22.28 and 18.61 years. This note details the successful accomplishment of this task.

  11. Stabilization of Taylor-Couette flow due to time-periodic outer cylinder oscillation

    NASA Technical Reports Server (NTRS)

    Murray, B. T.; Mcfadden, G. B.; Coriell, S. R.

    1990-01-01

    The linear stability of circular Couette flow between concentric infinite cylinders is considered for the case when the inner cylinder is rotated at a constant angular velocity and the outer cylinder is driven sinusoidally in time with zero mean rotation. This configuration was studied experimentally by Walsh and Donnelly. The critical Reynolds numbers calculated from linear stability theory agree well with the experimental values, except at large modulation amplitudes and small frequencies. The theoretical values are obtained using Floquet theory implemented in two distinct approaches: a truncated Fourier series representation in time, and a fundamental solution matrix based on a Chebyshev pseudospectral representation in space. For large amplitude, low frequency modulation, the linear eigenfunctions are temporally complex, consisting of a quiescent region followed by rapid change in the perturbed flow velocities.

  12. [Systematization of the experiences of 2 years of work. Arimao Population Council].

    PubMed

    Martínez Pérez, M

    1998-01-01

    The community and social participation as an action has been part of the daily life every group and community. A descriptive and qualitative study of the 2-year period 1994-1996 was conducted to determine the hygienic, sanitary, socioeconomic, sports, cultural and health transformation occurred at the circumscription # 73 of the ABalcón Arimao@ People's Council, in La Lisa municipality, which is located in an insalubrious suburb with a high criminal rate, school dropout and unemployment, that is subjected to social actions. The method of Experience Systematization of Oscar Hara in 5 times was applied and included in the living process of this community in addition to life histories. The most important achievement was to gather all the social members of the community, with their mobilization capacity, under the leadership of the main conductors of the process through an innovative methodology starting from its context. Positive changes were observed in the life style and the health status of the population.

  13. Time-Perception Network and Default Mode Network Are Associated with Temporal Prediction in a Periodic Motion Task.

    PubMed

    Carvalho, Fabiana M; Chaim, Khallil T; Sanchez, Tiago A; de Araujo, Draulio B

    2016-01-01

    The updating of prospective internal models is necessary to accurately predict future observations. Uncertainty-driven internal model updating has been studied using a variety of perceptual paradigms, and have revealed engagement of frontal and parietal areas. In a distinct literature, studies on temporal expectations have also characterized a time-perception network, which relies on temporal orienting of attention. However, the updating of prospective internal models is highly dependent on temporal attention, since temporal attention must be reoriented according to the current environmental demands. In this study, we used functional magnetic resonance imaging (fMRI) to evaluate to what extend the continuous manipulation of temporal prediction would recruit update-related areas and the time-perception network areas. We developed an exogenous temporal task that combines rhythm cueing and time-to-contact principles to generate implicit temporal expectation. Two patterns of motion were created: periodic (simple harmonic oscillation) and non-periodic (harmonic oscillation with variable acceleration). We found that non-periodic motion engaged the exogenous temporal orienting network, which includes the ventral premotor and inferior parietal cortices, and the cerebellum, as well as the presupplementary motor area, which has previously been implicated in internal model updating, and the motion-sensitive area MT+. Interestingly, we found a right-hemisphere preponderance suggesting the engagement of explicit timing mechanisms. We also show that the periodic motion condition, when compared to the non-periodic motion, activated a particular subset of the default-mode network (DMN) midline areas, including the left dorsomedial prefrontal cortex (DMPFC), anterior cingulate cortex (ACC), and bilateral posterior cingulate cortex/precuneus (PCC/PC). It suggests that the DMN plays a role in processing contextually expected information and supports recent evidence that the DMN may

  14. Time-Perception Network and Default Mode Network Are Associated with Temporal Prediction in a Periodic Motion Task.

    PubMed

    Carvalho, Fabiana M; Chaim, Khallil T; Sanchez, Tiago A; de Araujo, Draulio B

    2016-01-01

    The updating of prospective internal models is necessary to accurately predict future observations. Uncertainty-driven internal model updating has been studied using a variety of perceptual paradigms, and have revealed engagement of frontal and parietal areas. In a distinct literature, studies on temporal expectations have also characterized a time-perception network, which relies on temporal orienting of attention. However, the updating of prospective internal models is highly dependent on temporal attention, since temporal attention must be reoriented according to the current environmental demands. In this study, we used functional magnetic resonance imaging (fMRI) to evaluate to what extend the continuous manipulation of temporal prediction would recruit update-related areas and the time-perception network areas. We developed an exogenous temporal task that combines rhythm cueing and time-to-contact principles to generate implicit temporal expectation. Two patterns of motion were created: periodic (simple harmonic oscillation) and non-periodic (harmonic oscillation with variable acceleration). We found that non-periodic motion engaged the exogenous temporal orienting network, which includes the ventral premotor and inferior parietal cortices, and the cerebellum, as well as the presupplementary motor area, which has previously been implicated in internal model updating, and the motion-sensitive area MT+. Interestingly, we found a right-hemisphere preponderance suggesting the engagement of explicit timing mechanisms. We also show that the periodic motion condition, when compared to the non-periodic motion, activated a particular subset of the default-mode network (DMN) midline areas, including the left dorsomedial prefrontal cortex (DMPFC), anterior cingulate cortex (ACC), and bilateral posterior cingulate cortex/precuneus (PCC/PC). It suggests that the DMN plays a role in processing contextually expected information and supports recent evidence that the DMN may

  15. Time-Perception Network and Default Mode Network Are Associated with Temporal Prediction in a Periodic Motion Task

    PubMed Central

    Carvalho, Fabiana M.; Chaim, Khallil T.; Sanchez, Tiago A.; de Araujo, Draulio B.

    2016-01-01

    The updating of prospective internal models is necessary to accurately predict future observations. Uncertainty-driven internal model updating has been studied using a variety of perceptual paradigms, and have revealed engagement of frontal and parietal areas. In a distinct literature, studies on temporal expectations have also characterized a time-perception network, which relies on temporal orienting of attention. However, the updating of prospective internal models is highly dependent on temporal attention, since temporal attention must be reoriented according to the current environmental demands. In this study, we used functional magnetic resonance imaging (fMRI) to evaluate to what extend the continuous manipulation of temporal prediction would recruit update-related areas and the time-perception network areas. We developed an exogenous temporal task that combines rhythm cueing and time-to-contact principles to generate implicit temporal expectation. Two patterns of motion were created: periodic (simple harmonic oscillation) and non-periodic (harmonic oscillation with variable acceleration). We found that non-periodic motion engaged the exogenous temporal orienting network, which includes the ventral premotor and inferior parietal cortices, and the cerebellum, as well as the presupplementary motor area, which has previously been implicated in internal model updating, and the motion-sensitive area MT+. Interestingly, we found a right-hemisphere preponderance suggesting the engagement of explicit timing mechanisms. We also show that the periodic motion condition, when compared to the non-periodic motion, activated a particular subset of the default-mode network (DMN) midline areas, including the left dorsomedial prefrontal cortex (DMPFC), anterior cingulate cortex (ACC), and bilateral posterior cingulate cortex/precuneus (PCC/PC). It suggests that the DMN plays a role in processing contextually expected information and supports recent evidence that the DMN may

  16. Stability of time periodic solution of the Navier-Stokes equation on the half-space under oscillatory moving boundary condition

    NASA Astrophysics Data System (ADS)

    Kagei, Yoshiyuki; Oomachi, Ryouta

    2016-09-01

    Navier-Stokes system on the half space with periodically oscillating boundary has a time periodic solution which depends on time variable and vertical variable only. It is proved that the time periodic solution is asymptotically stable when the Reynolds number is sufficiently small; and the decay estimates of the perturbations are established in the frameworks of both strong and weak solutions.

  17. Tantalum trabecular metal implants in anterior cervical corpectomy and fusion: 2-year prospective analysis.

    PubMed

    King, V; Swart, A; Winder, M J

    2016-10-01

    Anterior cervical decompression for two or more cervical spondylotic levels can be performed using either multiple anterior cervical discectomies and fusion or anterior cervical corpectomy and fusion (ACCF). A variety of options for ACCF implants exist but to our knowledge, there is no clinical data for the use of tantalum trabecular metal implants (TTMI) for ACCF. A retrospective review was performed of prospectively collected data for ten patients undergoing ACCF with TTMI between 2011 and 2012. Radiological outcome was assessed by measuring the change in cervical (C) lordosis (fusion Cobb and C2-C7 Cobb), graft subsidence (anterior/posterior, determined by the subsidence of anterior/posterior body height of fused segments; cranial/caudal, determined by the cranial/caudal plate-to-disc distances) and rate of fusion using lateral cervical X-rays of patients at 0, 6, 12 and 24months post-operatively. The Neck Disability Index (NDI) assessed clinical outcome pre-operatively and at 6, 12 and 24months post-operatively. Cervical lordosis (Cobb angle of fused segment) was 5.2° (± 4.2°) at 0months and 6.0° (± 5.7°) at 24months post-operatively. Graft subsidence was observed to occur at 6months post-operatively and continued throughout follow-up. Anterior, posterior and caudal subsidence occurred more in the first 12months post-operatively than in the following 12months (p<0.05). Average pre-operative NDI was 45%. Average NDIs were 18%, 13% and 10% at 6, 12 and 24months post-operatively, respectively. ACCF patients treated with TTMI demonstrated stable cervical lordosis over 2years of follow-up and 100% fusion rates after 2years. Measures of subsidence appeared to decrease with time. Patients experienced improved clinical outcomes over the 2-year period. PMID:27515543

  18. Nonparametric decomposition of quasi-periodic time series for change-point detection

    NASA Astrophysics Data System (ADS)

    Artemov, Alexey; Burnaev, Evgeny; Lokot, Andrey

    2015-12-01

    The paper is concerned with the sequential online change-point detection problem for a dynamical system driven by a quasiperiodic stochastic process. We propose a multicomponent time series model and an effective online decomposition algorithm to approximate the components of the models. Assuming the stationarity of the obtained components, we approach the change-point detection problem on a per-component basis and propose two online change-point detection schemes corresponding to two real-world scenarios. Experimental results for decomposition and detection algorithms for synthesized and real-world datasets are provided to demonstrate the efficiency of our change-point detection framework.

  19. Predicting attenuant and resonant 2-cycles in periodically forced discrete-time two-species population models.

    PubMed

    Morena, Matthew A; Franke, John E

    2012-01-01

    Periodic environments may either enhance or suppress a population via resonant or attenuant cycles. We derive signature functions for predicting the responses of two competing populations to 2-periodic oscillations in six model parameters. Two of these parameters provide a non-trivial equilibrium and two provide the carrying capacities of each species in the absence of the other, but the remaining two are arbitrary and could be intrinsic growth rates. Each signature function is the sign of a weighted sum of the relative strengths of the oscillations of the perturbed parameters. Periodic environments are favourable for populations when the signature function is positive and are deleterious if the signature function is negative. We compute the signature functions of four classical, discrete-time two-species populations and determine regions in parameter space which are either favourable or detrimental to the populations. The six-parameter models include the Logistic, Ricker, Beverton-Holt, and Hassell models.

  20. Wavelets, period-doubling, and time-frequency localization with application to organization of convection over the tropical western Pacific

    NASA Technical Reports Server (NTRS)

    Weng, Hengyi; Lau, K.-M.

    1994-01-01

    In this paper, preliminary results in using orthogonal and continuous wavelet transform (WT) to identify period doubling and time-frequency localization in both synthetic and real data are presented. First, the Haar WT is applied to synthetic time series derived from a simple nonlinear dynamical system- a first-order quadratic difference equation. Second, the complex Morlet WT is used to study the time-frequency localization of tropical convection based on a high-resolution Japanese Geostationary Meteorological Satellite infrared (IR) radiance dataset. The Haar WT of the synthetic time series indicates the presence and distinct separation of multiple frequencies in a period-doubling sequence. The period-doubling process generates a multiplicity of intermediate frequencies, which are manifested in the nonuniformity in time with respect to the phase of oscillations in the lower frequencies. Wavelet transform also enables the detection of extremely weak signals in high-order subharmonics resulting from the period-doubling bifurcations. These signals are either undetected or considered statistically insignificant by traditional Fourier analysis. The Morlet WT of the IR radiance dataset indicates the presence of multiple timescales, which are localized in both frequency and time. There are two regimes in the variation of IR radiance, corresponding to the wet and dry periods. Multiple timescales, ranging from semidiurnal, diurnal, synoptic, to intraseasonal with embedding structures, are active in the wet regime. In particular, synoptic variability is more prominent during the wet phase of an intensive intraseasonal cycle. These are not only consistent with, but also show more details than, previous findings by using other techniques. The phase-locking relationships among the oscillations with different time-scales suggest that both synoptic and intraseasonal variations may be mixed oscillations due to the interaction of self-excited oscillations in the tropical

  1. Frequency decoding of periodically timed action potentials through distinct activity patterns in a random neural network

    NASA Astrophysics Data System (ADS)

    Reichenbach, Tobias; Hudspeth, A. J.

    2012-11-01

    Frequency discrimination is a fundamental task of the auditory system. The mammalian inner ear, or cochlea, provides a place code in which different frequencies are detected at different spatial locations. However, a temporal code based on spike timing is also available: action potentials evoked in an auditory-nerve fiber by a low-frequency tone occur at a preferred phase of the stimulus—they exhibit phase locking—and thus provide temporal information about the tone's frequency. Humans employ this temporal information for discrimination of low frequencies. How might such temporal information be read out in the brain? Here we employ statistical and numerical methods to demonstrate that recurrent random neural networks in which connections between neurons introduce characteristic time delays, and in which neurons require temporally coinciding inputs for spike initiation, can perform sharp frequency discrimination when stimulated with phase-locked inputs. Although the frequency resolution achieved by such networks is limited by the noise in phase locking, the resolution for realistic values reaches the tiny frequency difference of 0.2% that has been measured in humans.

  2. High-order fuzzy time-series based on multi-period adaptation model for forecasting stock markets

    NASA Astrophysics Data System (ADS)

    Chen, Tai-Liang; Cheng, Ching-Hsue; Teoh, Hia-Jong

    2008-02-01

    Stock investors usually make their short-term investment decisions according to recent stock information such as the late market news, technical analysis reports, and price fluctuations. To reflect these short-term factors which impact stock price, this paper proposes a comprehensive fuzzy time-series, which factors linear relationships between recent periods of stock prices and fuzzy logical relationships (nonlinear relationships) mined from time-series into forecasting processes. In empirical analysis, the TAIEX (Taiwan Stock Exchange Capitalization Weighted Stock Index) and HSI (Heng Seng Index) are employed as experimental datasets, and four recent fuzzy time-series models, Chen’s (1996), Yu’s (2005), Cheng’s (2006) and Chen’s (2007), are used as comparison models. Besides, to compare with conventional statistic method, the method of least squares is utilized to estimate the auto-regressive models of the testing periods within the databases. From analysis results, the performance comparisons indicate that the multi-period adaptation model, proposed in this paper, can effectively improve the forecasting performance of conventional fuzzy time-series models which only factor fuzzy logical relationships in forecasting processes. From the empirical study, the traditional statistic method and the proposed model both reveal that stock price patterns in the Taiwan stock and Hong Kong stock markets are short-term.

  3. Body-condition indices are repeatable across short, but not long, time periods in crimson finches Neochmia phaeton.

    PubMed

    Milenkaya, O; Legge, S; Walters, J R

    2014-01-01

    Abstract It is common in evolutionary ecology to interpret body-condition indices as indicators of individual quality, but this hypothesized relationship has been questioned and remains poorly validated. Here, we test one of the fundamental predictions of this condition-quality hypothesis, that relative-condition indices are repeatable within individuals, that is, that the index score of an individual relative to others is consistent over time. We sampled crimson finches (Neochmia phaeton) for seven commonly used condition indices and tested whether individual condition relative to conspecifics in the same context (e.g., breeding stage) was repeatable. We calculated the relative indices' repeatability across several temporal scales, from short (within breeding season) to long (more than 2 yr) time periods, as well as without consideration of timescale. Most relative-condition indices were repeatable when sampled without consideration of timescale, all were repeatable within a short time period, and none were repeatable over the longest time period. This provides only partial support for the condition-quality hypothesis, because although relative-condition indices were generally repeatable, this was primarily attributed to short-term, instead of long-term, repeatability. Condition indices may be meaningful indicators of short-term survival or fitness potential, but our findings are inconsistent with the idea that condition indices are indicators of inherent individual quality.

  4. A multivariate time-frequency method to characterize the influence of respiration over heart period and arterial pressure

    NASA Astrophysics Data System (ADS)

    Orini, Michele; Bailón, Raquel; Laguna, Pablo; Mainardi, Luca T.; Barbieri, Riccardo

    2012-12-01

    Respiratory activity introduces oscillations both in arterial pressure and heart period, through mechanical and autonomic mechanisms. Respiration, arterial pressure, and heart period are, generally, non-stationary processes and the interactions between them are dynamic. In this study we present a methodology to robustly estimate the time course of cross spectral indices to characterize dynamic interactions between respiratory oscillations of heart period and blood pressure, as well as their interactions with respiratory activity. Time-frequency distributions belonging to Cohen's class are used to estimate time-frequency (TF) representations of coherence, partial coherence and phase difference. The characterization is based on the estimation of the time course of cross spectral indices estimated in specific TF regions around the respiratory frequency. We used this methodology to describe the interactions between respiration, heart period variability (HPV) and systolic arterial pressure variability (SAPV) during tilt table test with both spontaneous and controlled respiratory patterns. The effect of selective autonomic blockade was also studied. Results suggest the presence of common underling mechanisms of regulation between cardiovascular signals, whose interactions are time-varying. SAPV changes followed respiratory flow both in supine and standing positions and even after selective autonomic blockade. During head-up tilt, phase differences between respiration and SAPV increased. Phase differences between respiration and HPV were comparable to those between respiration and SAPV during supine position, and significantly increased during standing. As a result, respiratory oscillations in SAPV preceded respiratory oscillations in HPV during standing. Partial coherence was the most sensitive index to orthostatic stress. Phase difference estimates were consistent among spontaneous and controlled breathing patterns, whereas coherence was higher in spontaneous breathing

  5. Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes.

    PubMed

    Mebrate, Yoseph; Willson, Keith; Manisty, Charlotte H; Baruah, Resham; Mayet, Jamil; Hughes, Alun D; Parker, Kim H; Francis, Darrel P

    2009-09-01

    We examine the potential to treat unstable ventilatory control (seen in periodic breathing, Cheyne-Stokes respiration, and central sleep apnea) with carefully controlled dynamic administration of supplementary CO(2), aiming to reduce ventilatory oscillations with minimum increment in mean CO(2). We used a standard mathematical model to explore the consequences of phasic CO(2) administration, with different timing and dosing algorithms. We found an optimal time window within the ventilation cycle (covering approximately 1/6 of the cycle) during which CO(2) delivery reduces ventilatory fluctuations by >95%. Outside that time, therapy is dramatically less effective: indeed, for more than two-thirds of the cycle, therapy increases ventilatory fluctuations >30%. Efficiency of stabilizing ventilation improved when the algorithm gave a graded increase in CO(2) dose (by controlling its duration or concentration) for more severe periodic breathing. Combining gradations of duration and concentration further increased efficiency of therapy by 22%. The (undesirable) increment in mean end-tidal CO(2) caused was 300 times smaller with dynamic therapy than with static therapy, to achieve the same degree of ventilatory stabilization (0.0005 vs. 0.1710 kPa). The increase in average ventilation was also much smaller with dynamic than static therapy (0.005 vs. 2.015 l/min). We conclude that, if administered dynamically, dramatically smaller quantities of CO(2) could be used to reduce periodic breathing, with minimal adverse effects. Algorithms adjusting both duration and concentration in real time would achieve this most efficiently. If developed clinically as a therapy for periodic breathing, this would minimize excess acidosis, hyperventilation, and sympathetic overactivation, compared with static treatment.

  6. Photometric Investigation and Possible Light-Time Effect in the Orbital Period of a Marginal Contact System, CW Cassiopeiae

    NASA Astrophysics Data System (ADS)

    Jiang, Tian-Yu; Li, Li-Fang; Han, Zhan-Wen; Jiang, Deng-Kai

    2010-04-01

    The first complete charge-coupled device (CCD) light curves in B and V passbands of a neglected contact binary system, CW Cassiopeiae (CW Cas), are presented. They were analyzed simultaneously by using the Wilson and Devinney (WD) code (1971, ApJ, 166, 605). The photometric solution indicates that CW Cas is a W-type W UMa system with a mass ratio of m2/m1 2.234, and that it is in a marginal contact state with a contact degree of ˜6.5% and a relatively large temperature difference of ˜327K between its two components. Based on the minimum times collected from the literature, together with the new ones obtained in this study, the orbital period changes of CW Cas were investigated in detail. It was found that a periodical variation overlaps with a secular period decrease in its orbital period. The long-term period decrease with a rate of dP/dt = -3.44 × 10-8d yr-1 can be interpreted either by mass transfer from the more-massive component to the less-massive with a rate of dm2/dt = -3.6 × 10-8M⊙ yr-1, or by mass and angular-momentum losses through magnetic braking due to a magnetic stellar wind. A low-amplitude cyclic variation with a period of T = 63.7 yr might be caused by the light-time effect due to the presence of a third body.

  7. Evaluation of the appropriate time period between sampling and analyzing for automated urinalysis

    PubMed Central

    Dolscheid-Pommerich, Ramona C.; Klarmann-Schulz, Ute; Conrad, Rupert; Stoffel-Wagner, Birgit; Zur, Berndt

    2016-01-01

    Introduction Preanalytical specifications for urinalysis must be strictly adhered to avoid false interpretations. Aim of the present study is to examine whether the preanalytical factor ‘time point of analysis’ significantly influences stability of urine samples for urine particle and dipstick analysis. Materials and methods In 321 pathological spontaneous urine samples, urine dipstick (Urisys™2400, Combur-10-Test™strips, Roche Diagnostics, Mannheim, Germany) and particle analysis (UF-1000 i™, Sysmex, Norderstedt, Germany) were performed within 90 min, 120 min and 240 min after urine collection. Results For urine particle analysis, a significant increase in conductivity (120 vs. 90 min: P < 0.001, 240 vs. 90 min: P < 0.001) and a significant decrease in WBC (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), RBC (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), casts (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001) and epithelial cells (120 vs. 90 min P = 0.610, 240 vs. 90 min P = 0.041) were found. There were no significant changes for bacteria. Regarding urine dipstick analysis, misclassification rates between measurements were significant for pH (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), leukocytes (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), nitrite (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), protein (120 vs. 90 min P < 0.001, 240 vs. 90 min P<0.001), ketone (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), blood (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001), specific gravity (120 vs. 90 min P < 0.001, 240 vs. 90 min P < 0.001) and urobilinogen (120 vs. 90 min, P = 0.031). Misclassification rates were not significant for glucose and bilirubin. Conclusion Most parameters critically depend on the time window between sampling and analysis. Our study stresses the importance of adherence to early time points in urinalysis (within 90 min). PMID:26981022

  8. Delay-dependent criteria for global robust periodicity of uncertain switched recurrent neural networks with time-varying delay.

    PubMed

    Lou, X; Cui, B

    2008-04-01

    In this paper, we introduce some ideas of switched systems into the field of neural networks and a large class of switched recurrent neural networks (SRNNs) with time-varying structured uncertainties and time-varying delay is investigated. Some delay-dependent robust periodicity criteria guaranteeing the existence, uniqueness, and global asymptotic stability of periodic solution for all admissible parametric uncertainties are devised by taking the relationship between the terms in the Leibniz-Newton formula into account. Because free weighting matrices are used to express this relationship and the appropriate ones are selected by means of linear matrix inequalities (LMIs), the criteria are less conservative than existing ones reported in the literature for delayed neural networks with parameter uncertainties. Some examples are given to show that the proposed criteria are effective and are an improvement over previous ones.

  9. Need for desiccant in containers exposed to atmospheric conditions for long periods of time

    SciTech Connect

    Mead, K.E.

    1981-11-01

    Current component and system designs are required to perform satisfactorily up to 25 years. A maximum leak rate of 1 x 10/sup -6/ cc(STP) helium/sec-atm is a frequent requirement for component containers. Calculations show that undesiccated component containers continuously exposed to 50% relative humidity at 20/sup 0/C and having an internal free volume of less than 300 cc and the above leak rate will allow the internal dew point to rise enough for potential liquid condensation in less than four years. For the same vapor pressure differential, the moisture permeation rate through one linear inch of silicone o-ring is 750 times as fast as moisture enters a welded container whose leak rate is 1 x 10/sup -6/ cc(STP) helium/sec-atm. For ethylene propylene o-ring material this ratio is about 13. These values correspond to the ratios of the quantities of desiccant required to maintain an acceptable dew point temperature when the moisture capacity of the free volume is not included. Charts are provided for estimating the amount of desiccant required for helium leak tested containers and for containers sealed with elastomeric o-rings.

  10. In vivo biocompatibility versus degree of conversion of resin-reinforced cements in different time periods.

    PubMed

    Lacerda-Santos, Rogério; De Farias, Maria Isabel Serpa Simões; De Carvalho, Fabiola Galbiatti; Pithon, Matheus Melo; Alves, Pollianna Muniz; Tanaka, Orlando Motohiro; Guênes, Gymenna Maria Tenório

    2014-05-01

    This study focused on test the null hypothesis that there is no difference between the degree of conversion and biocompatibility of different resin reinforced glass ionomer cements (RRGICs). Forty-eight male Wistar rats were used, distributed into four groups (n = 12), as follows: Group C (Control, polyethylene), Group FOB (Fuji Ortho Band), Group UBL (Ultra band Lok), and Group MCG (Multicure Glass), in subcutaneous tissue. The events of edema, necrosis, granulation tissue, multinuclear giant cells, young fibroblasts, and collagen formation were analyzed at 7, 15, and 30 days. The degree of conversion was evaluated by the Fourier method. Biocompatibility and degree of conversion were assessed using the Kruskal-Wallis and Dunn tests, and ANOVA and Tukey's test, respectively (P < 0.05). It was observed that, there was significant difference between Groups FOB and UBL for the presence of young fibroblasts at 15 days (P = 0.034) and between the Control and MCG Groups for the presence of multinucleated giant cells at 30 days (P = 0.009). Monomer conversion increased progressively until day 30, with significant difference between Group FOB and Groups UBL and MCG (P = 0.013) at 15 days. The null hypothesis was partially accepted, Fuji Ortho Band showed a less monomer conversion and a smaller number of young fibroblasts in the time of 15 days. PMID:24615757

  11. Periodicity and dissipativity for memristor-based mixed time-varying delayed neural networks via differential inclusions.

    PubMed

    Duan, Lian; Huang, Lihong

    2014-09-01

    In this paper, we investigate a class of memristor-based neural networks with general mixed delays involving both time-varying delays and distributed delays. By using the Mawhin-like coincidence theorem, together with the differential inclusion theory, M-matrix properties and differential inequality techniques, some novel criteria are established for ensuring the periodicity and dissipativity for the addressed neural networks. Finally, two numerical examples with simulations are presented to demonstrate the effectiveness of the theoretical results.

  12. Hydrodynamics, temperature/salinity variability and residence time in the Chilika lagoon during dry and wet period: Measurement and modeling

    NASA Astrophysics Data System (ADS)

    Mahanty, M. M.; Mohanty, P. K.; Pattnaik, A. K.; Panda, U. S.; Pradhan, S.; Samal, R. N.

    2016-08-01

    This paper investigated the hydrodynamics, spatio-temporal variability of temperature/salinity and the residence time of tracer concentrations in a largest brackish water coastal lagoon in Asia, namely the Chilika lagoon, India. An integrated approach combined the measurement and 2D hydrodynamic-advection/dispersion model is used to simulate circulation and temperature/salinity, and estimated the water residence time in lagoon under different forcing mechanisms, such as tide, wind and freshwater discharge during the dry and wet periods. Water circulation inside the lagoon is simulated when wind is included with the tide only forcing during dry period, and freshwater influx is included with the tide and wind forcing during wet period. Under the realistic forcing conditions, the computed temporal variability of water temperature and salinity are well correlated with the measurements in both the periods. The spatial variations of water temperature within the lagoon is influenced by the meteorological conditions, tide and freshwater influx as well as the shallowness of the lagoon, whereas the salinity is spatially controlled by the freshwater influx from the riverine system and seawater intrusion through the tidal inlets. The numerical model results show that in the Chilika lagoon tidal and river influx affect significantly the residence time spatially, and is site specific. The residence time varies from values of 4-5 days in the outer channel (OC) and 132 days at the northern sector (NS) in the main body of lagoon. The current study represents a first attempt to use a combined model approach, which is therefore, a useful tool to support the ecological implication of the lagoon ecosystem.

  13. Identifying Thermally Challenging Landscapes and Time Periods for Wildlife Using Remote Sensing

    NASA Astrophysics Data System (ADS)

    Albright, T. P.; Pidgeon, A.; Radeloff, V.; Wardlow, B.

    2011-12-01

    Recent events and climate model outputs indicate an increase in the occurrence and magnitude of heat waves and other high temperature events in many locations. Temperatures at the land surface may be much higher than air temperatures making this a particularly relevant consideration for animals that nest, forage, or seek refuge at or near the ground. Often associated with heat waves are prolonged and/or rapid onset drought events, which can combine to place stress on vegetation and animals. In order to assess the influence of heat waves and drought on communities of birds, we developed statistical models between avian abundance and species richness data collected by volunteer observers as part of the North American Breeding Bird Survey and a suite of precipitation and temperature metrics. We used station data, gridded standardized precipitation indices, and remotely sensed vegetation indices, and developed an index of accumulated temperature exceedance using time series MODIS land surface temperature (LST) products. Mixed effects models accounting for nuisance factors and temporal autocorrelation revealed that LST was among the strongest predictors of same year and following-year avian abundance. In particular, declines in abundance were largest and most common among ground-nesting birds and long-distance migrants in the US Southwest. In cooler regions, high LST exceedances were sometimes associated with increases in abundance. Because these results do not indicate whether dispersal, reproductive effort, or mortality explain the changes, one area of current research focuses on identifying demographic mechanisms and population consequences of such responses. A second area of active research focuses on using LST data in conjunction with digital elevation models and derivatives and dense networks of ground-level observations to produce physiologically-relevant indicators of thermally stressful conditions for birds and other animals.

  14. On the evaluation of the time of periodical dissolution of a dispersed material in a rotor-pulse device

    NASA Astrophysics Data System (ADS)

    Fedorov, A. V.; Shul'Gin, A. V.; Vasilishin, M. S.; Ivanova, D. B.; Ivanov, O. S.; Karpov, A. G.

    2011-07-01

    Results are presented of experimental and numerical investigations of the kinetics of periodical dissolution of benzoic and salicylic acids in water using the rotor-pulse device. It is found that the process obeys the firstorder kinetics. A determining influence of the rotation frequency of the device rotor and the size of the radial gap between the rotor and the stator on the dissolution time is shown. Favorable agreement between the experimental and calculated time dependences for the concentration of the dissolved substance are obtained.

  15. Age-Period-Cohort Analysis of 1990–2003 Incidence Time Trends of Childhood Diabetes in Italy

    PubMed Central

    Bruno, Graziella; Maule, Milena; Merletti, Franco; Novelli, Giulia; Falorni, Alberto; Iannilli, Antonio; Iughetti, Lorenzo; Altobelli, Emma; d'Annunzio, Giuseppe; Piffer, Silvano; Pozzilli, Paolo; Iafusco, Dario; Songini, Marco; Roncarolo, Federico; Toni, Sonia; Carle, Flavia; Cherubini, Valentino

    2010-01-01

    OBJECTIVE To investigate age-period-cohort effects on the temporal trend of type 1 diabetes in children age 0–14 years in Italian registries. RESEARCH DESIGN AND METHODS This report is based on 5,180 incident cases in the period 1990–2003 from the Registry for Type 1 Diabetes Mellitus in Italy (RIDI). Multilevel (random intercept) Poisson regression models were used to model the effects of sex, age, calendar time, and birth cohorts on temporal trends, taking into account the registry-level variance component. RESULTS The incidence rate was 12.26 per 100,000 person-years and significantly higher in boys (13.13 [95% CI 12.66–13.62]) than in girls (11.35 [10.90–11.82]). Large geographical variations in incidence within Italy were evident; incidence was highest in Sardinia, intermediate in Central-Southern Italy, and high in Northern Italy, particularly in the Trento Province, where the incidence rate was 18.67 per 100,000 person-years. An increasing temporal trend was evident (2.94% per year [95% CI 2.22–3.67]). With respect to the calendar period 1990–1992, the incidence rates increased linearly by 15, 27, 35, and 40% in the following time periods (P for trend < 0.001). With respect to the 1987–1993 birth cohort, the incidence rate ratio increased approximately linearly from 0.63 (95% CI 0.54–0.73) in the 1975–1981 cohort to 1.38 (1.06–1.80) in the 1999–2003 cohort. The best model, however, included sex, age, and a linear time trend (drift). CONCLUSIONS Large geographical variations and an increasing temporal trend in diabetes incidence are evident among type 1 diabetic children in Italy. Age-period-cohort analysis shows that the variation over time has a linear component that cannot be ascribed to either the calendar period or the birth cohort. PMID:20566665

  16. Social contact patterns of school-age children in Taiwan: comparison of the term time and holiday periods.

    PubMed

    Chen, S-C; You, Z-S

    2015-04-01

    School closure is one of the most common interventions in the early weeks of an influenza pandemic. Few studies have investigated social contact patterns and compared individual student contact characteristics during the school term and holiday periods in Taiwan. Here, we conducted a well-used questionnaire survey in a junior high school (grades 7-8) in June 2013. All 150 diary-based effective questionnaires covering conversation and skin-to-skin contact behaviour were surveyed. Two questionnaires for each participant were designed to investigate the individual-level difference of contact numbers per day during the two periods. The questionnaire response rate was 44%. The average number of contacts during term time (20·0 contacts per day) and holiday periods (12·6 contacts per day) were significantly different (P < 0·05). The dominant contact frequencies and duration were everyday contact (89·10%) and contacts lasting less than 5 minutes (37·09%). The greatest differences occurred within the 13-19 years age groups. The result presented in this study provide an indication of the likely reduction in daily contact frequency that might occur if a school closure policy was adopted in the event of an influenza pandemic in Taiwan. Comparing contact patterns during term time and holiday periods, the number of contacts decreased by 40%. This study is the first research to investigate the contact numbers and contact characteristics for school-age children during the school term and a holiday period in Taiwan. With regard to public health, this study could provide the basic contact information and database for modelling influenza epidemics for minimizing the spread of influenza that depends on personal contacts for transmission. PMID:25078611

  17. A two-time-period comparison of the effects of ambient air pollution on outpatient visits for acute respiratory illnesses.

    PubMed

    Sinclair, Amber Hughes; Edgerton, Eric S; Wyzga, Ron; Tolsma, Dennis

    2010-02-01

    Concentrations of numerous ambient air pollutants have declined in recent years across the United States. Although it can be expected that reductions in air pollutants are associated with reductions in health effects, it is unclear whether this is actually the case. The purpose of this analysis was to compare the levels of and relationships between air pollutants and acute respiratory outpatient visits for two consecutive time periods totaling 53 mo. Air pollution data were collected at a centrally located monitor in Atlanta, GA, and include 24-hr averages of particulate matter (PM) less than 2.5 microm in aerodynamic diameter (PM2.5) and its components; coarse PM (PM10-2.5); PM less than 10 microm in aerodynamic diameter (PM10); oxygenated volatile organic compounds (OVOCs); 8-hr maximum ozone (O3); and 1-hr maximum nitrogen dioxide (NO2), carbon monoxide (CO), and sulfur dioxide (SO2). In addition, several metals and fractions of elemental carbon (EC) and organic carbon (OC) were investigated. Daily outpatient visit data were obtained from the electronic data warehouse of the Atlanta-based region of a nonprofit managed care organization. Poisson general linear modeling determined associations between daily levels of acute visits for four diagnosis groups (adult and child asthma, upper and lower respiratory infection) and air pollution measurements. Overall declining trends were observed in air pollutants and acute visits over the study period. Childhood asthma had the greatest number of significant associations with air pollutants, namely zinc and EC. The significant lag time between pollutant measurement and visit occurrence changed from 3-5 days in the first time period to 6-8 days in the later time period, but there was general consistency in several childhood asthma and pollutant associations over both time periods. The greatest evidence for a reduction in pollution being associated with an improvement in health response was for lower respiratory disease

  18. 20 CFR 216.75 - When a child is a full-time student during a period of non-attendance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When a child is a full-time student during a... full-time student during a period of non-attendance. A student who has been in full-time attendance at an elementary or secondary school is considered a full-time student during a period of...

  19. Variability in stream discharge and temperatures during ecologically sensitive time periods: a preliminary assessment of the implications for Atlantic salmon

    NASA Astrophysics Data System (ADS)

    Tetzlaff, D.; Soulsby, C.; Youngson, A. F.; Gibbins, C.; Bacon, P. J.; Malcolm, I. A.; Langan, S.

    2005-05-01

    This study focused on improving the understanding of the temporal variability in hydrological and thermal conditions and their potential influences on two life stages of Atlantic salmon (Salmo salar) - stream resident juveniles and returning adult spawners. Stream discharges and temperatures in the Girnock Burn, NE Scotland, a small nursery stream, were characterised over a time period of ten hydrological years (1994/95-2003/04). Frequency, magnitude, duration and timing of thermal, hydraulic and hydrological conditions were examined using data with a high temporal resolution (hourly and subhourly). Particular attention was focussed on assessing variations during ecologically sensitive time periods when salmon behaviour is most susceptible to environmental perturbations. The Girnock Burn was characterised by a strong inter- and intra-annual variability in the hydrological and thermal regime. This has clear implications for the likely feeding opportunities for juvenile fish in winter and early spring and the emergence of fry in the late spring. The movement of adult spawners towards breeding areas showed a complex dependence on hydrological variability. If discharges were low, fish movement was increasingly triggered by suboptimal flow increases as spawning time approached. Elucidating links between discharge/temperature variability and salmon habitat availability and utilization at appropriately fine temporal scales is a prerequisite to the development of better conservation management strategies and more biologically meaningful flow regimes in regulated river systems.

  20. Design and analysis strategies for digital repetitive control systems with time-varying reference/disturbance period

    NASA Astrophysics Data System (ADS)

    Costa-Castelló, R.; Olm, J. M.; Ramos, G. A.

    2011-07-01

    This article analyses stability and performance features of different design schemes for digital repetitive control systems subject to references/disturbances that exhibit non-uniform frequency. Aiming at maintaining a constant value for the ratio T p /T s , T p being the period of the reference/disturbance signal and T s being the sampling period, two approaches are proposed. The first one deals with the real-time adaptation of T s to the actual changes of T p ; stability is studied by means of an LMI gridding method and also using robust control techniques. The second one propounds the introduction of an additional compensator that annihilates the effect of the time-varying sampling in the closed-loop system and forces its behaviour to coincide with that of an a priori selected nominal sampling period; the internal stability of the compensator-plant subsystem is checked by means of LMI gridding. The theoretical results are experimentally tested and compared through a mechatronic plant model.

  1. Discrete infinite-dimensional type-K monotone dynamical systems and time-periodic reaction-diffusion systems

    NASA Astrophysics Data System (ADS)

    Liang, Xing; Jiang, Jifa

    The asymptotic behavior of discrete type-K monotone dynamical systems and reaction-diffusion equations is investigated. The studying content includes the index theory for fixed points, permanence, global stability, convergence everywhere and coexistence. It is shown that the system has a globally asymptotically stable fixed point if every fixed point is locally asymptotically stable with respect to the face it belongs to and at this point the principal eigenvalue of the diagonal partial derivative about any component not belonging to the face is not one. A nice result presented is the sufficient and necessary conditions for the system to have a globally asymptotically stable positive fixed point. It can be used to establish the sufficient conditions for the system to persist uniformly and the convergent result for all orbits. Applications are made to time-periodic Lotka-Volterra systems with diffusion, and sufficient conditions for such systems to have a unique positive periodic solution attracting all positive initial value functions are given. For more general time-periodic type-K monotone reaction-diffusion systems with spatial homogeneity, a simple condition is given to guarantee the convergence of all positive solutions.

  2. Altering Transplantation Time to Avoid Periods of High Temperature Can Efficiently Reduce Bacterial Wilt Disease Incidence with Tomato.

    PubMed

    Wei, Zhong; Huang, Jian-Feng; Hu, Jie; Gu, Yi-An; Yang, Chun-Lan; Mei, Xin-Lan; Shen, Qi-Rong; Xu, Yang-Chun; Friman, Ville-Petri

    2015-01-01

    Tomato bacterial wilt caused by Ralstonia solanacearum bacterium is a severe problem in Southern China, where relatively high environmental temperatures commonly prevails during the crop seasons. Previous research has indicated that bacterial wilt disease incidence generally increases during the warm months of summer leading to reduced tomato yield. Moreover, the efficacy of bio-organic fertilizers (BOFs)-organic compost fortified with pathogen-suppressive bacteria-is often lost during the periods of high environmental temperatures. Here we studied if the disease incidence could be reduced and the BOF performance enhanced by simply preponing and postponing the traditional seedling transplantation times to avoid tomato plant development during periods of high environmental temperature. To this end, a continuous, two-year field experiment was conducted to evaluate the performance of BOF in two traditional (late-spring [LS] and early-autumn [EA]) and two alternative (early-spring [ES] and late-autumn [LA]) crop seasons. We found that changing the transplantation times reduced the mean disease incidence from 33.9% (LS) and 54.7% (EA) to 11.1% (ES) and 7.1% (LA), respectively. Reduction in disease incidence correlated with the reduction in R. Solanacearum pathogen density in the tomato plant rhizosphere and stem base. Applying BOF during alternative transplantation treatments improved biocontrol efficiency from 43.4% (LS) and 3.1% (EA) to 67.4% (ES) and 64.8% (LA). On average, the mean maximum air temperatures were positively correlated with the disease incidence, and negatively correlated with the BOF biocontrol efficacy over the crop seasons. Crucially, even though preponing the transplantation time reduced the tomato yield in general, it was still economically more profitable compared to LS season due to reduced crop losses and relatively higher market prices. Preponing and postponing traditional tomato transplantation times to cooler periods could thus offer simple

  3. Alcohol Consumption and Liver Disease in Australia: A Time Series Analysis of the Period 1935–2006

    PubMed Central

    Jiang, Heng; Livingston, Michael; Room, Robin; Dietze, Paul; Norström, Thor; Kerr, William C.

    2014-01-01

    Aims: The aim of the study was to examine for Australia whether the link between population alcohol consumption and liver disease mortality varies over time, using 71 years of data. Methods: Overall and gender-specific rates of liver disease mortality were analysed in relation to total alcohol consumption as well as for different beverage types by using autoregressive integrated moving average (ARIMA) time series methods. Separate models were developed for the entire time period and for two sub-periods (1935–1975, 1976–2006). Results: A 1-l increase in adult per capita consumption of pure alcohol led to a rise of ∼10% in overall liver disease mortality rates and a 11 and 9% increase in female and male liver disease mortality, respectively. The strength of the relationship between per capita consumption and liver disease mortality diminished over time. Spirits consumption was found to be the main driving factor in liver mortality rates between 1935 and 1975, while beer consumption was found to be the most significant predictor in liver diseases in the last three decades. In a comparative perspective, the effect of per capita alcohol consumption on liver disease in Australia is similar to the USA, Southern and Eastern Europe countries, but weaker than in Canada and western European countries. Conclusion: An increase in per capita alcohol consumption in Australia is likely to lead to an increase in liver disease. Changes in the most important beverage over the study period suggest substantial shifts in drinking patterns and preferences among the heaviest Australian drinkers. PMID:24052533

  4. Altering Transplantation Time to Avoid Periods of High Temperature Can Efficiently Reduce Bacterial Wilt Disease Incidence with Tomato

    PubMed Central

    Wei, Zhong; Huang, Jian-Feng; Hu, Jie; Gu, Yi-An; Yang, Chun-Lan; Mei, Xin-Lan; Shen, Qi-Rong; Xu, Yang-Chun; Friman, Ville-Petri

    2015-01-01

    Tomato bacterial wilt caused by Ralstonia solanacearum bacterium is a severe problem in Southern China, where relatively high environmental temperatures commonly prevails during the crop seasons. Previous research has indicated that bacterial wilt disease incidence generally increases during the warm months of summer leading to reduced tomato yield. Moreover, the efficacy of bio-organic fertilizers (BOFs)–organic compost fortified with pathogen-suppressive bacteria—is often lost during the periods of high environmental temperatures. Here we studied if the disease incidence could be reduced and the BOF performance enhanced by simply preponing and postponing the traditional seedling transplantation times to avoid tomato plant development during periods of high environmental temperature. To this end, a continuous, two-year field experiment was conducted to evaluate the performance of BOF in two traditional (late-spring [LS] and early-autumn [EA]) and two alternative (early-spring [ES] and late-autumn [LA]) crop seasons. We found that changing the transplantation times reduced the mean disease incidence from 33.9% (LS) and 54.7% (EA) to 11.1% (ES) and 7.1% (LA), respectively. Reduction in disease incidence correlated with the reduction in R. Solanacearum pathogen density in the tomato plant rhizosphere and stem base. Applying BOF during alternative transplantation treatments improved biocontrol efficiency from 43.4% (LS) and 3.1% (EA) to 67.4% (ES) and 64.8% (LA). On average, the mean maximum air temperatures were positively correlated with the disease incidence, and negatively correlated with the BOF biocontrol efficacy over the crop seasons. Crucially, even though preponing the transplantation time reduced the tomato yield in general, it was still economically more profitable compared to LS season due to reduced crop losses and relatively higher market prices. Preponing and postponing traditional tomato transplantation times to cooler periods could thus offer

  5. Existence and global exponential stability of periodic solution of memristor-based BAM neural networks with time-varying delays.

    PubMed

    Li, Hongfei; Jiang, Haijun; Hu, Cheng

    2016-03-01

    In this paper, we investigate a class of memristor-based BAM neural networks with time-varying delays. Under the framework of Filippov solutions, boundedness and ultimate boundedness of solutions of memristor-based BAM neural networks are guaranteed by Chain rule and inequalities technique. Moreover, a new method involving Yoshizawa-like theorem is favorably employed to acquire the existence of periodic solution. By applying the theory of set-valued maps and functional differential inclusions, an available Lyapunov functional and some new testable algebraic criteria are derived for ensuring the uniqueness and global exponential stability of periodic solution of memristor-based BAM neural networks. The obtained results expand and complement some previous work on memristor-based BAM neural networks. Finally, a numerical example is provided to show the applicability and effectiveness of our theoretical results.

  6. Proportional spike-timing precision and firing reliability underlie efficient temporal processing of periodicity and envelope shape cues.

    PubMed

    Zheng, Y; Escabí, M A

    2013-08-01

    Temporal sound cues are essential for sound recognition, pitch, rhythm, and timbre perception, yet how auditory neurons encode such cues is subject of ongoing debate. Rate coding theories propose that temporal sound features are represented by rate tuned modulation filters. However, overwhelming evidence also suggests that precise spike timing is an essential attribute of the neural code. Here we demonstrate that single neurons in the auditory midbrain employ a proportional code in which spike-timing precision and firing reliability covary with the sound envelope cues to provide an efficient representation of the stimulus. Spike-timing precision varied systematically with the timescale and shape of the sound envelope and yet was largely independent of the sound modulation frequency, a prominent cue for pitch. In contrast, spike-count reliability was strongly affected by the modulation frequency. Spike-timing precision extends from sub-millisecond for brief transient sounds up to tens of milliseconds for sounds with slow-varying envelope. Information theoretic analysis further confirms that spike-timing precision depends strongly on the sound envelope shape, while firing reliability was strongly affected by the sound modulation frequency. Both the information efficiency and total information were limited by the firing reliability and spike-timing precision in a manner that reflected the sound structure. This result supports a temporal coding strategy in the auditory midbrain where proportional changes in spike-timing precision and firing reliability can efficiently signal shape and periodicity temporal cues.

  7. Using time scales to characterize phytoplankton assemblages in a deep subalpine lake during the thermal stratification period: Lake Iseo, Italy

    NASA Astrophysics Data System (ADS)

    Marti, Clelia Luisa; Imberger, Jörg; Garibaldi, Letizia; Leoni, Barbara

    2016-03-01

    A combination of field observations and 3-D hydrodynamic simulations were used to identify the phytoplankton species and to estimate the various time scales of the dominant physical and biological processes in Lake Iseo, a deep subalpine lake located in northern Italy, during a stratified period (July 2010). By ordering the rate processes time scales, we derive a phytoplankton patch categorization and growth interpretation that provides a general framework for the spatial distribution of phytoplankton concentration in Lake Iseo and illuminates the characteristics of their ecological niches. The results show that the diurnal surface layer was well mixed, received strong diurnal radiation, had low phosphorus concentrations and the phytoplankton biomass was sustained by the green alga Sphaerocystis schroeterii. The vertical mixing time scales were much shorter than horizontal mixing time scales causing a depth-uniform chlorophyll a concentration. The horizontal patch scale was determined by horizontal dispersion balancing the phytoplankton growth time scale, dictating the success of the observed green algae. The strongly stratified nutrient-rich metalimnion had mild light conditions and Diatoma elongatum and Planktothrix rubescens made up the largest proportions of the total phytoplankton biomass at the intermediate and deeper metalimnetic layers. The vertical transport time scales were much shorter than horizontal transport and vertical dispersion leading to growth niche for the observed phytoplankton. The study showed that time-scale hierarchy mandates the essential phytoplankton attributes or traits for success in a particular section of the water column and/or water body.

  8. Medical Care and Your 1- to 2-Year-Old

    MedlinePlus

    ... Zika & Pregnancy Medical Care and Your 1- to 2-Year-Old KidsHealth > For Parents > Medical Care and Your 1- to 2-Year-Old Print A A A Text Size ... Following simple instructions? Saying a few words? Combining two words by age 2? The doctor may ask ...

  9. Controlling access time to a high-fat diet during the inactive period protects against obesity in mice.

    PubMed

    Haraguchi, Atsushi; Aoki, Natsumi; Ohtsu, Teiji; Ikeda, Yuko; Tahara, Yu; Shibata, Shigenobu

    2014-10-01

    Free feeding (FF) with a high fat diet (HFD) causes excessive body weight gain, whereas restricted feeding (RF) with a HFD attenuates body weight gain. The effects of timing of feeding with a HFD (day vs. night) and feeding duration on energy homeostasis have not yet been investigated. In this study, we fed mice a HFD or a normal diet (ND) twice a day, during their active and inactive periods, on a schedule. The amount of food was regulated by feeding duration (2, 4 or 8 h). First, we investigated the effects of 4-h RF during active-inactive periods (ND-ND, HFD-HFD, ND-HFD or HFD-ND). Among all the 4-h RF groups, mice consumed almost the same amount of calories as those in the FF[ND] group, even those fed a HFD. Body weight and visceral fat in these three groups were lower than that in the FF[HFD] group. Second, we investigated the effects of RF duration. Body weight and visceral fat were higher in the 8-h groups than in the 4-h groups. Body weight and visceral fat were higher in the 2-h groups than in the 4-h groups even though the 2-h groups had less food. Third, we investigated the effects of eating a HFD during the inactive period, when RF duration was extended (2, 6 or 12 h). Mice were fed with a HFD during the inactive period for 2 h and fed with a ND during the active period for 2, 6 or 12 h. Body weight and visceral fat in these mice were comparable to those in the FF[ND] mice. The results of our first set of experiments suggest that 4-h RF was an adequate feeding duration to control the effect of a HFD on obesity. The results of our second set of experiments suggest 2-h RF (such as speed-eating) and 8-h RF, representative of eating disorders, are unhealthy feeding patterns related to obesity. The results of our third set of experiments suggest that eating a HFD for a short period during the night does not affect body weight and visceral fat. Taken together, these results indicate that consideration to feeding with a HFD during the inactive period and

  10. Statistical Methods for Protecting Personally Identifiable Information in the Disclosure of Graduation Rates of First-Time, Full-Time Degree- or Certificate-Seeking Undergraduate Students by 2-Year Degree-Granting Institutions of Higher Education. Technical Brief. NCES 2012-151

    ERIC Educational Resources Information Center

    Chen, Xianglei; Bersudskaya, Vera; Cubarrubi, Archie

    2011-01-01

    The Higher Education Opportunity Act of 2008 (HEOA) requires that Title IV degree-granting institutions disclose annually the graduation rates of first-time, full-time degree- or certificate-seeking undergraduate students, disaggregated by gender, each major racial/ethnic subgroup, and receipt or non-receipt of a federal Pell grant or subsidized…

  11. One period coupon bond valuation with revised first passage time approach and the application in Indonesian corporate bond

    NASA Astrophysics Data System (ADS)

    Maruddani, Di Asih I.; Rosadi, Dedi; Gunardic, Abdurakhman

    2015-02-01

    The value of a corporate bond is conventionally expressed in terms of zero coupon bond. In practice, the most common form of debt instrument is coupon bond and allows early default before maturity as safety covenant for the bondholder. This paper study valuation for one period coupon bond, a coupon bond that only give one time coupon at the bond period. It assumes that the model give bondholder the right to reorganize a firm if its value falls below a given barrier. Revised first passage time approach is applied for default time rule. As a result, formulas of equity, liability, and probability of default is derived for this specified model. Straightforward integration under risk neutral pricing is used for deriving those formulas. For the application, bond of Bank Rakyat Indonesia (BRI) as one of the largest bank in Indonesia is analyzed. R computing show that value of the equity is IDR 453.724.549.000.000, the liability is IDR 2.657.394.000.000, and the probability if default is 5.645305E-47 %.

  12. Asymptomatic inhaled foreign body. A bullet in the lung for 2 years.

    PubMed

    Salim, Muhammad U; Asghar, Asif; Tareen, Irum; Azhar, Muhammad

    2016-10-01

    It is very rare to have a big foreign body in the lungs without any complications or symptoms for 2 years. A 14-year-old male with episodes of minor hemoptysis for 4 weeks had a history of inhalation of a bullet 2 years earlier. He had asymptomatic for lung complications for 2 years. The bullet was removed by right thoracotomy and  non-anatomical wedge stapled resection, and he followed an uneventful recovery. An aspirated foreign body although big can remain asymptomatic for a long time, especially if it has migrated to the periphery. PMID:27652366

  13. Construction and properties of a topological index for periodically driven time-reversal invariant 2D crystals

    NASA Astrophysics Data System (ADS)

    Carpentier, D.; Delplace, P.; Fruchart, M.; Gawędzki, K.; Tauber, C.

    2015-07-01

    We present mathematical details of the construction of a topological invariant for periodically driven two-dimensional lattice systems with time-reversal symmetry and quasienergy gaps, which was proposed recently by some of us. The invariant is represented by a gap-dependent Z2-valued index that is simply related to the Kane-Mele invariants of quasienergy bands but contains an extra information. As a byproduct, we prove new expressions for the two-dimensional Kane-Mele invariant relating the latter to Wess-Zumino amplitudes and the boundary gauge anomaly.

  14. Sexual abstinence in patients with HIV infection: a 2-year follow-up study.

    PubMed

    Jordan, W C

    1991-12-01

    Thirty-five human immunodeficiency virus (HIV)-positive patients were followed over a 2-year period. All agreed to abstain from sexual intercourse. This group had a low level of recurring infections. A comparison study of sexually active HIV males is underway.

  15. In-plane time-harmonic elastic wave motion and resonance phenomena in a layered phononic crystal with periodic cracks.

    PubMed

    Golub, Mikhail V; Zhang, Chuanzeng

    2015-01-01

    This paper presents an elastodynamic analysis of two-dimensional time-harmonic elastic wave propagation in periodically multilayered elastic composites, which are also frequently referred to as one-dimensional phononic crystals, with a periodic array of strip-like interior or interface cracks. The transfer matrix method and the boundary integral equation method in conjunction with the Bloch-Floquet theorem are applied to compute the elastic wave fields in the layered periodic composites. The effects of the crack size, spacing, and location, as well as the incidence angle and the type of incident elastic waves on the wave propagation characteristics in the composite structure are investigated in details. In particular, the band-gaps, the localization and the resonances of elastic waves are revealed by numerical examples. In order to understand better the wave propagation phenomena in layered phononic crystals with distributed cracks, the energy flow vector of Umov and the corresponding energy streamlines are visualized and analyzed. The numerical results demonstrate that large energy vortices obstruct elastic wave propagation in layered phononic crystals at resonance frequencies. They occur before the cracks reflecting most of the energy transmitted by the incoming wave and disappear when the problem parameters are shifted from the resonant ones.

  16. Walls of Time: The "Walk through Time" Was Inspired by How Artists of Various Time Periods and Cultures Have Decorated Walls

    ERIC Educational Resources Information Center

    Komrska, Shelley; Rupe, Melissa

    2005-01-01

    Last year, a school embarked on a school-wide project that would take all of their students, kindergarten through-sixth grade, through a tangible art timeline. The result was a passageway--over seventy-five feet in length--that revealed the history of art, from cave painting to modern-day graffiti art. The "walk through time" was inspired by how…

  17. Duty periods with early start times restrict the amount of sleep obtained by short-haul airline pilots.

    PubMed

    Roach, Gregory D; Sargent, Charli; Darwent, David; Dawson, Drew

    2012-03-01

    Most of the research related to human fatigue in the aviation industry has focussed on long-haul pilots, but short-haul pilots also experience elevated levels of fatigue. The aim of this study was to examine the impact of early start times on the amount of sleep obtained prior to duty and on fatigue levels at the start of duty. Seventy short-haul pilots collected data regarding their duty schedule and sleep/wake behaviour for at least two weeks. Data were collected using self-report duty/sleep diaries and wrist activity monitors. Mixed-effects regression analyses were used to examine the effects of duty start time (04:00-10:00 h) on (i) the total amount of sleep obtained in the 12h prior to the start of duty and (ii) self-rated fatigue level at the start of duty. Both analyses indicated significant main effects of duty start time. In particular, the amount of sleep obtained in the 12h prior to duty was lowest for duty periods that commenced between 04:00 and 05:00 h (i.e. 5.4h), and greatest for duty periods that commenced between 09:00 and 10:00 h (i.e. 6.6h). These data indicate that approximately 15 min of sleep is lost for every hour that the start of duty is advanced prior to 09:00 h. In addition, self-rated fatigue at the start of duty was highest for duty periods that commenced between 04:00 and 05:00 h, and lowest for duty periods that commenced between 09:00 and 10:00 h. Airlines should implement a fatigue risk management system (FRMS) for short-haul pilots required to work early-morning shifts. One component of the FRMS should be focussed on the production of 'fatigue-friendly' rosters. A second component of the FRMS should be focussed on training pilots to optimise sleep opportunities, to identify circumstances where the likelihood of fatigue is elevated, and to manage the risks associated with fatigue-related impairment.

  18. How well does WWLLN reproduce the satellite-observed distribution of flashes during the 2007-2012 time period?

    NASA Astrophysics Data System (ADS)

    Allen, D. J.; Pickering, K. E.; Ring, A.; Holzworth, R. H.

    2013-12-01

    Lightning is the dominant source of nitrogen oxides (NOx) involved in the production of ozone in the middle and upper troposphere in the tropics and in summer in the midlatitudes. Therefore it is imperative that the lightning NOx (LNOx) source strength per flash be better constrained. This process requires accurate information on the location and timing of lightning flashes. In the past fifteen years satellite-based lightning monitoring by the Optical Transient Detector (OTD) and Lightning Imaging Sensor (LIS) has greatly increased our understanding of the global distribution of lightning as a function of season and time-of-day. However, detailed information at higher temporal resolutions is only available for limited regions where ground-based networks such as the United States National Lightning Detection Network (NLDN) exist. In 2004, the ground-based World Wide Lightning Location Network (WWLLN) was formed with the goal of providing continuous flash rate information over the entire globe. It detects very low frequency (VLF) radio waves emitted by lightning with a detection efficiency (DE) that varies with stroke energy, time-of-day, surface type, and network coverage. This study evaluated the DE of WWLLN strokes relative to climatological OTD/LIS flashes using data from the 2007 to 2012 time period, a period during which the mean number of working sensors increased from 28 to 53. The analysis revealed that the mean global DE increased from 5% in 2007 to 13% in 2012. Regional variations were substantial with mean 2012 DEs of 5-10% over much of Argentina, Africa, and Asia and 15-30% over much of the Atlantic, Pacific, and Indian Oceans, the United States and the Maritime Continent. Detection-efficiency adjusted WWLLN flash rates were then compared to NLDN-based flash rates. Spatial correlations for individual summer months ranged from 0.66 to 0.93. Temporal correlations are currently being examined for regions of the U.S. and will also be shown.

  19. Finite difference time domain modeling of finite-sized electromagnetic source over periodic structure via a plane wave spectral expansion approach

    NASA Astrophysics Data System (ADS)

    Qiang, Rui; Chen, Ji; Yang, Fan

    2010-10-01

    A novel three-dimensional time domain method is developed to study interactions between finite-sized electromagnetic sources and infinite periodic structures. The method is based on a periodic finite difference time domain method combined with the spectral expansion of electromagnetic sources. Using this method, only a single periodic cell needs to be modeled in finite difference time domain simulations. The convergence, guidelines on using the algorithm, and the acceleration scheme for the algorithm are discussed. Several periodic structures are simulated by this proposed method. It is shown that this method can significantly reduce the required computer memory and computational time.

  20. Solubility of Two Root-End Filling Materials over Different Time Periods in Synthetic Tissue Fluid: a Comparative Study

    PubMed Central

    Shojaee, Nooshin Sadat; Sahebi, Safoora; Karami, Elahe; Sobhnamayan, Fereshte

    2015-01-01

    Statement of the Problem Insolubility is an important criterion for an ideal root-end filling material to both prevent any microleakage between the root canal and the periradicular space and provide sealing ability. Purpose Many recent studies have shown that mineral trioxide aggregate (MTA) and calcium-enriched mixture (CEM) have acceptable sealing ability. The purpose of this in vitro study was to evaluate the solubility of these root-end filling materials. Materials and Method Forty stainless steel ring moulds with an internal diameter of 10±1 mm and a height of 2±0.1 mm were selected. Samples of MTA and CEM were mixed according to the manufacturer’s instructions and inserted into the moulds. The specimens were divided into 4 experimental groups and kept in synthetic tissue fluid (STF) for 2 different time periods (7 and 28 days). The control group contained 8 empty rings. The moulds’ weights were recorded before and after immersion in STF. The changes in the weight of the samples were measured and compared using a two- way ANOVA test at a significance level of 5%. Specimens were evaluated with scanning electron microscopy (SEM) at a magnification of 500×. Results There was no significant difference in weight changes between MTA and CEM samples (p> 0.05). Conclusion MTA and CEM have similar solubility in STF in different time periods. PMID:26331148

  1. Financial Impact of Allogeneic Hematopoietic Cell Transplantation on Patients and Families over 2-years: Results from a Multicenter Pilot Study

    PubMed Central

    Denzen, Ellen M.; Thao, Viengneesee; Hahn, Theresa; Lee, Stephanie J.; McCarthy, Philip L.; Rizzo, J. Douglas; Ammi, Monique; Drexler, Rebecca; Flesch, Susan; James, Heather; Omondi, Nancy; Murphy, Elizabeth; Pederson, Kate; Majhail, Navneet S.

    2016-01-01

    Hematopoietic cell transplantation (HCT) is a procedure that can significantly influence the socioeconomic wellbeing of patients, caregivers and their families. Among 30 allogeneic HCT recipients and their caregivers enrolled on a pilot study evaluating the feasibility of studying financial impact of HCT, 16 agreed to participate in the long-term phase, completed a baseline questionnaire and received phone interviews at 6, 12, 18 and 24 months post-HCT. Analyses showed that by 2-years post-HCT, 54% of patients who previously contributed to household earnings had not returned to work and 80% of patients/caregivers reported transplant as having moderate to great impact on household income. However, patients’ level of confidence in their ability to meet household financial obligations increased from baseline to 2-years. A relatively large proportion of patients reported inability to pay for medical care through this time period. Case studies demonstrated patient individual perception of financial impact of HCT varies considerably, regardless of actual income. We demonstrate the feasibility of conducting a study to evaluate financial impact of allogeneic HCT through 2-years post-transplantation. Some patients/caregivers continue to experience significant long-term financial burden after this procedure. Our study lays the foundation for a larger evaluation of patient/caregiver financial burden associated with HCT. PMID:27088381

  2. Environmental Modifications and 2-Year Measured and Self-reported Stair-Use: A Worksite Randomized Trial

    PubMed Central

    Linde, Jennifer A.; Cousins, Julie M.; Jeffery, Robert W.

    2014-01-01

    Environmental modifications have been shown to increase short-term stair use, longer-term success is unclear. This study assessed the 2-year effectiveness of an environmental intervention promoting worksite stair use. We assessed stair use at work by means of self-reports and infrared beam counters (which send a safe and invisible beam of infrared light from one side of a stairwell to a reflector on the other side; when an individual uses the stairs, the infrared beam is disrupted and an instance of stair use is recorded) at six worksites (three intervention, three control) in a group randomized, controlled worksite weight-gain prevention trial in Minneapolis/St. Paul, MN. Intervention modifications were signs encouraging stair use, music, and art posters in stairwells. We collected data before environmental modifications (2006–2007) and at the end of the 2-year intervention (2008–2009). The intervention had a significant positive effect on stair use measured both objectively and via self-report, with greatest increases reported among those participants who used the stairs least at baseline. Following 2-years of continuously-maintained stairwell modifications, increases in both objectively-measured and self-reported stair use were significantly larger at intervention than control worksites. Study findings suggest that the positive impact of environmental modifications on stair use persist over a longer time period than has been previously demonstrated. Results also indicate that infrequent stair users may be most amenable to the behavior changes encouraged by these environmental enhancements. PMID:23979097

  3. Cost and Schedule Analytical Techniques Development: Option 2 Year

    NASA Technical Reports Server (NTRS)

    1997-01-01

    This Final Report summarizes the activities performed by Science Applications International Corporation (SAIC) for the Option 2 Year from December 1, 1996 through November 30, 1997. The Final Report is in compliance with Paragraph 5 of Section F of the contract. This CSATD contract provides products and deliverable in the form of models, data bases, methodologies, studies and analyses for the NASA Marshall Space Flight Center's (MSFC) Engineering Cost Office (PPO3) the Program Plans and Requirements Officer (PP02), and other user organizations. Detailed Monthly Progress reports were submitted to MSFC in accordance with the contract's Statement of Work, Section TV "Reporting and Documentation". These reports spelled out each month's specific work accomplishments, deliverables submitted, major meetings held, and other pertinent information. This Final Report will summarize these activities at higher level. During this contract Option Year, SAIC expended 29,830 man-hours in tile performance of tasks called out in the Statement of Work and reported oil in this yearly Final Report. This represents approximately 16 full-time EPs. Included are the basis Huntsville-based team, plus SAIC specialists in San Diego, Ames Research Center, Chicago, and Colorado Springs performing specific tasks for which they are uniquely qualified.

  4. Time trend and age-period-cohort effect on kidney cancer mortality in Europe, 1981–2000

    PubMed Central

    Pérez-Farinós, Napoleón; López-Abente, Gonzalo; Pastor-Barriuso, Roberto

    2006-01-01

    Background The incorporation of diagnostic and therapeutic improvements, as well as the different smoking patterns, may have had an influence on the observed variability in renal cancer mortality across Europe. This study examined time trends in kidney cancer mortality in fourteen European countries during the last two decades of the 20th century. Methods Kidney cancer deaths and population estimates for each country during the period 1981–2000 were drawn from the World Health Organization Mortality Database. Age- and period-adjusted mortality rates, as well as annual percentage changes in age-adjusted mortality rates, were calculated for each country and geographical region. Log-linear Poisson models were also fitted to study the effect of age, death period, and birth cohort on kidney cancer mortality rates within each country. Results For men, the overall standardized kidney cancer mortality rates in the eastern, western, and northern European countries were 20, 25, and 53% higher than those for the southern European countries, respectively. However, age-adjusted mortality rates showed a significant annual decrease of -0.7% in the north of Europe, a moderate rise of 0.7% in the west, and substantial increases of 1.4% in the south and 2.0% in the east. This trend was similar among women, but with lower mortality rates. Age-period-cohort models showed three different birth-cohort patterns for both men and women: a decrease in mortality trend for those generations born after 1920 in the Nordic countries, a similar but lagged decline for cohorts born after 1930 in western and southern European countries, and a continuous increase throughout all birth cohorts in eastern Europe. Similar but more heterogeneous regional patterns were observed for period effects. Conclusion Kidney cancer mortality trends in Europe showed a clear north-south pattern, with high rates on a downward trend in the north, intermediate rates on a more marked rising trend in the east than in the

  5. Reflection and transmission of a wave incident on a slab with a time-periodic dielectric function {epsilon}(t)

    SciTech Connect

    Zurita-Sanchez, Jorge R.; Halevi, P.; Cervantes-Gonzalez, Juan C.

    2009-05-15

    We present a theoretical description of the response of a dynamic slab, with time-periodic dielectric function {epsilon}(t), to a normally incident monochromatic plane wave of frequency {omega}{sub o}. As a consequence of the interaction of this incoming wave with the dynamic slab, the reflected and transmitted waves contain harmonics of the modulating frequency {omega}, namely, the slab itself becomes a polychromatic source of frequencies {omega}{sub o}-n{omega}(n=0,{+-}1,{+-}2,...). We establish a general formalism to quantify the reflected and transmitted fields for any periodic variation in the dielectric function. To achieve this, a description of wave propagation in a dynamic bulk is needed. A theoretical framework to treat such propagation, based on the concept of a temporal photonic crystal, is developed. As a consequence of the Bloch-Floquet theorem, the dispersion relation is a band structure that is periodic with frequency and exhibits forbidden wave vector gaps. The Poynting vectors of the transmitted and reflected fields are analyzed in detail. Our theory is applied to the case in which the dielectric function is modulated sinusoidally. We calculate numerically the magnitudes and phases of the reflection and transmission coefficients for several harmonics {omega}{sub o}-n{omega} and slab thicknesses. Three modulation regimes are considered: weak, moderate, and strong. The response in the weak regime is similar to that of a Fabry-Perot etalon--the strengths of the harmonics are weak. For the strong-modulation regime, the strengths of reflection and transmission coefficients of the harmonics become large; they can even exceed one due to the openness of the system in which an external modulating agent can provide part of the invested energy. Dynamic variation in the dielectric properties of materials can give rise to new effects in wave propagation and to novel optical applications and is readily attainable with present-day technology.

  6. Numerical investigation of multiple stationary and time-periodic flow regimes in vertical rotating disc CVD reactors

    NASA Astrophysics Data System (ADS)

    Gakis, G. P.; Koronaki, E. D.; Boudouvis, A. G.

    2015-12-01

    The vertical rotating disc CVD reactor problem is revisited with a computational framework that allows systematic parameter continuation along branches of flow regimes over various operating parameter values. The commercial CFD code Fluent is used, enhanced with a home-made module and by appropriate initialization, a P-ω diagram is mapped out. In addition to the well known result where boyancy-induced and rotation-induced regimes exist for low and high rotation rates respectively along with a favorable for film uniformity plug flow regime in between, interesting new flow regimes are computed: Stable time-periodic buoyancy induced flows are found as well as stationary ones. Periodic buoyancy induced flows co-exist with stationary plug flow regimes over a range of ω for pressures higher than 200 Torr. A regime of stationary flows where the effect of buoyancy and rotation is combined is computed at pressures higher than 350 Torr and it shown to co-exist with typical rotation induced flows.

  7. Global paths of time-periodic solutions of the Benjamin-Ono equation connecting arbitrary traveling waves

    SciTech Connect

    Ambrose, David M.; Wilkening, Jon

    2008-12-11

    We classify all bifurcations from traveling waves to non-trivial time-periodic solutions of the Benjamin-Ono equation that are predicted by linearization. We use a spectrally accurate numerical continuation method to study several paths of non-trivial solutions beyond the realm of linear theory. These paths are found to either re-connect with a different traveling wave or to blow up. In the latter case, as the bifurcation parameter approaches a critical value, the amplitude of the initial condition grows without bound and the period approaches zero. We propose a conjecture that gives the mapping from one bifurcation to its counterpart on the other side of the path of non-trivial solutions. By experimentation with data fitting, we identify the form of the exact solutions on the path connecting two traveling waves, which represents the Fourier coefficients of the solution as power sums of a finite number of particle positions whose elementary symmetric functions execute simple orbits in the complex plane (circles or epicycles). We then solve a system of algebraic equations to express the unknown constants in the new representation in terms of the mean, a spatial phase, a temporal phase, four integers (enumerating the bifurcation at each end of the path) and one additional bifurcation parameter. We also find examples of interior bifurcations from these paths of already non-trivial solutions, but we do not attempt to analyze their algebraic structure.

  8. Drift Compression and Final Focus for Intense Heavy Ion Beams with Non-periodic, Time-dependent Lattice

    SciTech Connect

    Hong Qin; Ronald C. Davidson; John J. Barnard; Edward P. Lee

    2005-02-14

    In the currently envisioned configurations for heavy ion fusion, it is necessary to longitudinally compress the beam bunches by a large factor after the acceleration phase. Because the space-charge force increases as the beam is compressed, the beam size in the transverse direction will increase in a periodic quadrupole lattice. If an active control of the beam size is desired, a larger focusing force is needed to confine the beam in the transverse direction, and a non-periodic quadrupole lattice along the beam path is necessary. In this paper, we describe the design of such a focusing lattice using the transverse envelope equations. A drift compression and final focus lattice should focus the entire beam pulse onto the same focal spot on the target. This is difficult with a fixed lattice, because different slices of the beam may have different perveance and emittance. Four time-dependent magnets are introduced in the upstream of drift compression to focus the entire pulse onto the sam e focal spot. Drift compression and final focusing schemes are developed for a typical heavy ion fusion driver and for the Integrated Beam Experiment (IBX) being designed by the Heavy Ion Fusion Virtual National Laboratory.

  9. Dynamic RSA: Examining parasympathetic regulatory dynamics via vector-autoregressive modeling of time-varying RSA and heart period.

    PubMed

    Fisher, Aaron J; Reeves, Jonathan W; Chi, Cyrus

    2016-07-01

    Expanding on recently published methods, the current study presents an approach to estimating the dynamic, regulatory effect of the parasympathetic nervous system on heart period on a moment-to-moment basis. We estimated second-to-second variation in respiratory sinus arrhythmia (RSA) in order to estimate the contemporaneous and time-lagged relationships among RSA, interbeat interval (IBI), and respiration rate via vector autoregression. Moreover, we modeled these relationships at lags of 1 s to 10 s, in order to evaluate the optimal latency for estimating dynamic RSA effects. The IBI (t) on RSA (t-n) regression parameter was extracted from individual models as an operationalization of the regulatory effect of RSA on IBI-referred to as dynamic RSA (dRSA). Dynamic RSA positively correlated with standard averages of heart rate and negatively correlated with standard averages of RSA. We propose that dRSA reflects the active downregulation of heart period by the parasympathetic nervous system and thus represents a novel metric that provides incremental validity in the measurement of autonomic cardiac control-specifically, a method by which parasympathetic regulatory effects can be measured in process.

  10. Global Characteristics of the Correlation and Time Lag Between Solar and Ionospheric Parameters in the 27-day Period

    NASA Technical Reports Server (NTRS)

    Lee, Choon-Ki; Han, Shin-Chan; Dieter,Bilitza; Ki-Weon,Seo

    2012-01-01

    The 27-day variations of topside ionosphere are investigated using the in-situ electron density measurements from the CHAMP planar Langmuir probe and GRACE K-band ranging system. As the two satellite systems orbit at the altitudes of approx. 370 km and approx. 480 km, respectively, the satellite data sets are greatly valuable for examining the electron density variations in the vicinity of F2-peak. In a 27-day period, the electron density measurements from the satellites are in good agreements with the solar flux, except during the solar minimum period. The time delays are mostly 1-2 day and represent the hemispherical asymmetry. The globally-estimated spatial patterns of the correlation between solar flux and in-situ satellite measurements show poor correlations in the (magnetic) equatorial region, which are not found from the ground measurements of vertically-integrated electron content. We suggest that the most plausible cause for the poor correlation is the vertical movement of ionization due to atmospheric dynamic processes that is not controlled by the solar extreme ultraviolet radiation.

  11. TIME DELAYS IN QUASI-PERIODIC PULSATIONS OBSERVED DURING THE X2.2 SOLAR FLARE ON 2011 FEBRUARY 15

    SciTech Connect

    Dolla, L.; Marque, C.; Seaton, D. B.; Dominique, M.; Berghmans, D.; Cabanas, C.; De Groof, A.; Verdini, A.; West, M. J.; Zhukov, A. N.; Van Doorsselaere, T.; Schmutz, W.; Zender, J.

    2012-04-10

    We report observations of quasi-periodic pulsations (QPPs) during the X2.2 flare of 2011 February 15, observed simultaneously in several wavebands. We focus on fluctuations on timescale 1-30 s and find different time lags between different wavebands. During the impulsive phase, the Reuven Ramaty High Energy Solar Spectroscopic Imager channels in the range 25-100 keV lead all the other channels. They are followed by the Nobeyama RadioPolarimeters at 9 and 17 GHz and the extreme-ultraviolet (EUV) channels of the Euv SpectroPhotometer (ESP) on board the Solar Dynamic Observatory. The zirconium and aluminum filter channels of the Large Yield Radiometer on board the Project for On-Board Autonomy satellite and the soft X-ray (SXR) channel of ESP follow. The largest lags occur in observations from the Geostationary Operational Environmental Satellite, where the channel at 1-8 A leads the 0.5-4 A channel by several seconds. The time lags between the first and last channels is up to Almost-Equal-To 9 s. We identified at least two distinct time intervals during the flare impulsive phase, during which the QPPs were associated with two different sources in the Nobeyama RadioHeliograph at 17 GHz. The radio as well as the hard X-ray channels showed different lags during these two intervals. To our knowledge, this is the first time that time lags are reported between EUV and SXR fluctuations on these timescales. We discuss possible emission mechanisms and interpretations, including flare electron trapping.

  12. Quiet-time periods observed by EPHIN/SOHO during the minimum of the 22nd solar cycle

    NASA Astrophysics Data System (ADS)

    Gómez-Herrero, Raúl; RodrÍguez-FrÍas, M. Dolores; del Peral, Luis; Sequeiros, Juan; Müller-Mellin, Reinhold; Kunow, Horst; Sierks, Holger

    2000-06-01

    An analysis of the hydrogen and helium isotopic composition from EPHIN data, during the quiet-time period from January 1 to June 1, 1996, is presented. An isotopic discrimination and background rejection have been applied and relationships between the abundances of ^2H/^1H, ^3He/^4He, and ^4He/^1H have been calculated. The energy spectra in the 4-50 MeV nucl^-1 range have been obtained and the contribution of the different spectral components have been analysed in this energy range. We conclude that the main contribution to the ^4He spectrum is of anomalous origin, while the proton and ^3He spectra have contributions mainly from particles of solar origin at low energies and from the galactic cosmic radiation modulated by the heliosphere at high energies. The deuterium spectrum is mainly of galactic origin.

  13. 17 CFR 270.32a-3 - Exemption from provision of section 32(a)(1) regarding the time period during which a registered...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... section 32(a)(1) regarding the time period during which a registered management investment company must....32a-3 Exemption from provision of section 32(a)(1) regarding the time period during which a registered management investment company must select an independent public accountant. (a) A registered...

  14. 17 CFR 270.32a-3 - Exemption from provision of section 32(a)(1) regarding the time period during which a registered...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... section 32(a)(1) regarding the time period during which a registered management investment company must....32a-3 Exemption from provision of section 32(a)(1) regarding the time period during which a registered management investment company must select an independent public accountant. (a) A registered...

  15. 17 CFR 270.32a-3 - Exemption from provision of section 32(a)(1) regarding the time period during which a registered...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... section 32(a)(1) regarding the time period during which a registered management investment company must....32a-3 Exemption from provision of section 32(a)(1) regarding the time period during which a registered management investment company must select an independent public accountant. (a) A registered...

  16. 20 CFR 1002.116 - Is the time period for reporting back to an employer extended if the employee is hospitalized for...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Is the time period for reporting back to an employer extended if the employee is hospitalized for, or convalescing from, an illness or injury incurred... Reemployment Application for Reemployment § 1002.116 Is the time period for reporting back to an...

  17. Time trend and age-period-cohort effects on gastric cancer incidence in Zaragoza and Navarre, Spain.

    PubMed Central

    Aragonés, N; Pollán, M; López-Abente, G; Ruiz, M; Vergara, A; Moreno, C; Moreo, P; Ardanaz, E

    1997-01-01

    STUDY OBJECTIVE: To describe time trends in gastric cancer incidence in Zaragoza and Navarre, and to investigate time period and birth cohort as determinants of such trends. DESIGN: Cases from two registries were grouped into five year intervals and the following were calculated: age specific and sex specific incidence rates, and the male to female ratio. Log linear models including age, period of diagnosis, and birth cohort were fitted. SETTING: The Zaragoza Cancer Registry covers the province of Zaragoza, which has a population of 824,776 (403,755 men and 421,021 women). The Navarre Cancer Registry covers the province of Navarre which has 512,512 inhabitants (254,786 men and 257,726 women). In both cases population figures were based on the late census. PATIENTS: These comprised incident cases of gastric cancer reported to the Zaragoza Cancer Registry in 1963-87 and to the Navarre Cancer Registry in 1973-87. MAIN RESULTS: Navarre registered higher adjusted and cumulative rates than Zaragoza for both sexes. In both provinces, there were relative declines in the rates for men and women of 3% and 4% respectively per year. In Zaragoza, the risk of developing stomach cancer fell in generations born between 1888 and 1933, and rose in subsequent birth cohorts in both sexes, while in Navarre the cohort effect showed an approximately linear risk for both sexes. Both provinces recorded increases in risk associated with cohorts born between 1933 and 1943. CONCLUSION: The incidence rates of gastric cancer fell in both Zaragoza and Navarre. The reason for the greater incidence of gastric cancer in Navarre remains unknown. Trends in rates seem to be mainly linked to birth cohort. Increases in risk in generations born after 1933 may be ascribable to nutritional deficiencies in the early years of life. PMID:9328549

  18. Transport of marked pebbles in short periods of time on a coarse clastic beach (Marina di Pisa, Italy)

    NASA Astrophysics Data System (ADS)

    Bertoni, D.; Ciavola, P.; Grottoli, E.; Sarti, G.

    2012-04-01

    Transport of coarse sediments on coarse clastic beaches still presents aspects that are not fully understood. For instance, there is a generally perceived notion that during fair-weather periods coarse grains hardly move, if not at all. The aim of this experiment is to prove that sediments such as pebbles are subject to significant shift in very short lapses of time and under low energy waves. An artificial coarse clastic beach at Marina di Pisa (Tuscany, Italy) was chosen as study site: Barbarossa beach is 110 m long and is bounded by two groynes. The mean grain size is about 40-to-50 mm. About 80 pebbles were marked by means of the RFID technology, which enables to univocally identify the tracers. The marked pebbles were released along cross-shore transects (one pebble each on the fair-weather berm, on the beachface and on the step crest) on the morning of September 15th, and two recovery campaigns were carried out after 6 and 24 hours from the injection. No particular wave activity was recorded during the time frame of the experiment. After the first recovery campaign, which was performed 6 hours later than the injection, about 94% of the pebbles were detected. After the second recovery campaign, 24 hours later, the recovery rate decreased to 89%. Considering that the technique provides for detection of tracers within 50 cm, the resulting loss of pebbles after so brief spans of time is remarkable. The lack of detection of few tracers implies that the transport rate that they experienced is not negligible. The highest rate of losses was recorded on the beachface, the zone that is subjected the most to waves even under calm conditions. Pebble movement is also confirmed by the fact that tracers detected after the first recovery campaign were not detected once again after the second recovery campaign, and vice versa. The results of the experiment are useful to better define the transport of coarse sediments, verifying that pebbles have to be expected be moving even

  19. On quality control procedures for solar radiation and meteorological measures, from subhourly to montly average time periods

    NASA Astrophysics Data System (ADS)

    Espinar, B.; Blanc, P.; Wald, L.; Hoyer-Klick, C.; Schroedter-Homscheidt, M.; Wanderer, T.

    2012-04-01

    Meteorological data measured by ground stations are often a key element in the development and validation of methods exploiting satellite images. These data are considered as a reference against which satellite-derived estimates are compared. Long-term radiation and meteorological measurements are available from a large number of measuring stations. However, close examination of the data often reveals a lack of quality, often for extended periods of time. This lack of quality has been the reason, in many cases, of the rejection of large amount of available data. The quality data must be checked before their use in order to guarantee the inputs for the methods used in modelling, monitoring, forecast, etc. To control their quality, data should be submitted to several conditions or tests. After this checking, data that are not flagged by any of the test is released as a plausible data. In this work, it has been performed a bibliographical research of quality control tests for the common meteorological variables (ambient temperature, relative humidity and wind speed) and for the usual solar radiometrical variables (horizontal global and diffuse components of the solar radiation and the beam normal component). The different tests have been grouped according to the variable and the average time period (sub-hourly, hourly, daily and monthly averages). The quality test may be classified as follows: • Range checks: test that verify values are within a specific range. There are two types of range checks, those based on extrema and those based on rare observations. • Step check: test aimed at detecting unrealistic jumps or stagnation in the time series. • Consistency checks: test that verify the relationship between two or more time series. The gathered quality tests are applicable for all latitudes as they have not been optimized regionally nor seasonably with the aim of being generic. They have been applied to ground measurements in several geographic locations, what

  20. Nonlinear stability of oscillatory core-annular flow: A generalized Kuramoto-Sivashinsky equation with time periodic coefficients

    NASA Technical Reports Server (NTRS)

    Coward, Adrian V.; Papageorgiou, Demetrios T.; Smyrlis, Yiorgos S.

    1994-01-01

    In this paper the nonlinear stability of two-phase core-annular flow in a pipe is examined when the acting pressure gradient is modulated by time harmonic oscillations and viscosity stratification and interfacial tension is present. An exact solution of the Navier-Stokes equations is used as the background state to develop an asymptotic theory valid for thin annular layers, which leads to a novel nonlinear evolution describing the spatio-temporal evolution of the interface. The evolution equation is an extension of the equation found for constant pressure gradients and generalizes the Kuramoto-Sivashinsky equation with dispersive effects found by Papageorgiou, Maldarelli & Rumschitzki, Phys. Fluids A 2(3), 1990, pp. 340-352, to a similar system with time periodic coefficients. The distinct regimes of slow and moderate flow are considered and the corresponding evolution is derived. Certain solutions are described analytically in the neighborhood of the first bifurcation point by use of multiple scales asymptotics. Extensive numerical experiments, using dynamical systems ideas, are carried out in order to evaluate the effect of the oscillatory pressure gradient on the solutions in the presence of a constant pressure gradient.

  1. Periodic Evolution of a Xe I Population in an Oscillatory Discharge Captured Through Time-Synchronized Laser Induced Fluorescence Techniques

    NASA Astrophysics Data System (ADS)

    Lucca Fabris, Andrea; Young, Christopher; Cappelli, Mark

    2014-10-01

    We track the evolution of the Xe I 6 s '[ 1 / 2 ] 1 - 6 p '[ 3 / 2 ] 2 (834.68 nm air) transition lineshape in a plasma discharge oscillating at 60 Hz. Two time-synchronized laser induced fluorescence techniques based on phase sensitive detection of the fluorescence signal are demonstrated, yielding consistent results. One approach used previously involves a sample-and-hold procedure that collects fluorescence signal at a particular phase in the oscillation period and holds the average value until the following sample. The second method is based on fast switching of the fluorescence signal; only the signal collected inside the acquisition gate is sent to a lock-in amplifier for processing. Both methods rely on modulating the exciting laser beam and the latter permits operation at a much higher frequency range with reduced spectral noise density. The maximum observed peak fluorescence intensity occurs at low discharge currents, although the peak intensity drops to zero at zero discharge current. The peak intensity also decreases at the discharge current maximum. Time-varying properties of the xenon neutrals are extracted from a lineshape analysis. This work is sponsored by the U.S. Air Force Office of Scientific Research with Dr. Mitat Birkan as program manager. CVY acknowledges support from the DOE NNSA Stewardship Science Graduate Fellowship under Contract DE-FC52-08NA28752.

  2. Orbit optimization and time delay interferometry for inclined ASTROD-GW formation with half-year precession-period

    NASA Astrophysics Data System (ADS)

    Wang, Gang; Ni, Wei-Tou

    2015-05-01

    ASTROD-GW (ASTROD [astrodynamical space test of relativity using optical devices] optimized for gravitational wave detection) is a gravitational-wave mission with the aim of detecting gravitational waves from massive black holes, extreme mass ratio inspirals (EMRIs) and galactic compact binaries together with testing relativistic gravity and probing dark energy and cosmology. Mission orbits of the 3 spacecrafts forming a nearly equilateral triangular array are chosen to be near the Sun-Earth Lagrange points L3, L4, and L5. The 3 spacecrafts range interferometrically with one another with arm length about 260 million kilometers. For 260 times longer arm length, the detection sensitivity of ASTROD-GW is 260 fold better than that of eLISA/NGO in the lower frequency region by assuming the same acceleration noise. Therefore, ASTROD-GW will be a better cosmological probe. In previous papers, we have worked out the time delay interferometry (TDI) for the ecliptic formation. To resolve the reflection ambiguity about the ecliptic plane in source position determination, we have changed the basic formation into slightly inclined formation with half-year precession-period. In this paper, we optimize a set of 10-year inclined ASTROD-GW mission orbits numerically using ephemeris framework starting at June 21, 2035, including cases of inclination angle with 0° (no inclination), 0.5°, 1.0°, 1.5°, 2.0°, 2.5°, and 3.0°. We simulate the time delays of the first and second generation TDI configurations for the different inclinations, and compare/analyse the numerical results to attain the requisite sensitivity of ASTROD-GW by suppressing laser frequency noise below the secondary noises. To explicate our calculation process for different inclination cases, we take the 1.0° as an example to show the orbit optimization and TDI simulation.

  3. AROME-WMED, a real-time mesoscale model designed for the HyMeX special observation periods

    NASA Astrophysics Data System (ADS)

    Fourrié, N.; Bresson, É.; Nuret, M.; Jany, C.; Brousseau, P.; Doerenbecher, A.; Kreitz, M.; Nuissier, O.; Sevault, E.; Bénichou, H.; Amodei, M.; Pouponneau, F.

    2015-07-01

    During autumn 2012 and winter 2013, two special observation periods (SOPs) of the HYdrological cycle in the Mediterranean EXperiment (HyMeX) took place. For the preparatory studies and to support the instrument deployment during the field campaign, a dedicated version of the operational convective-scale Application of Research to Operations at Mesoscale (AROME)-France model was developed: the AROME-WMED (West Mediterranean Sea) model. It covers the western Mediterranean basin with a 48 h forecast range. It provided real-time analyses and forecasts which were sent daily to the HyMeX operational centre to forecast high-precipitation events and to help decision makers on the deployment of meteorological instruments. This paper presents the main features of this numerical weather prediction system in terms of data assimilation and forecast. Some specific data of the HyMeX SOP were assimilated in real time. The forecast skill of AROME-WMED is then assessed with objective scores and compared to the operational AROME-France model, for both autumn 2012 (05 September to 06 November 2012) and winter 2013 (01 February to 15 March 2013) SOPs. The overall performance of AROME-WMED is good for the first HyMeX special observation period (SOP1) (i.e. mean 2 m temperature root mean square error (RMSE) of 1.7 °C and mean 2 m relative humidity RMSE of 10 % for the 0-30 h forecast ranges) and similar to those of AROME-France for the 0-30 h common forecast range (maximal absolute difference of 2 m temperature RMSE of 0.2 °C and 0.21 % for the 2 m relative humidity); conversely, for the 24-48 h forecast range it is less accurate (relative loss between 10 and 12 % in 2 m temperature and relative humidity RMSE, and equitable threat score (ETS) for 24 h accumulated rainfall), but it remains useful for scheduling observation deployment. The characteristics of parameters, such as precipitation, temperature or humidity, are illustrated by one heavy precipitation case study that occurred

  4. Climate regime shifts in paleoclimate time series from the Yucatán Peninsula: from the Preclassic to Classic period

    NASA Astrophysics Data System (ADS)

    Polanco Martínez, Josue M.; Medina-Elizalde, Martin; Burns, Stephen J.; Jiang, Xiuyang; Shen, Chuan-Chou

    2015-04-01

    It has been widely accepted by the paleoclimate and archaeology communities that extreme climate events (especially droughts) and past climate change played an important role in the cultural changes that occurred in at least some parts of the Maya Lowlands, from the Pre-Classic (2000 BC to 250 AD) to Post-Classic periods (1000 to 1521 AD) [1, 2]. In particular, a large number of studies suggest that the decline of the Maya civilization in the Terminal Classic Period was greatly influenced by prolonged severe drought events that probably triggered significant societal disruptions [1, 3, 4, 5]. Going further on these issues, the aim of this work is to detect climate regime shifts in several paleoclimate time series from the Yucatán Peninsula (México) that have been used as rainfall proxies [3, 5, 6, 7]. In order to extract information from the paleoclimate data studied, we have used a change point method [8] as implemented in the R package strucchange, as well as the RAMFIT method [9]. The preliminary results show for all the records analysed a prominent regime shift between 400 to 200 BCE (from a noticeable increase to a remarkable fall in precipitation), which is strongest in the recently obtained stalagmite (Itzamna) delta18-O precipitation record [7]. References [1] Gunn, J. D., Matheny, R. T., Folan, W. J., 2002. Climate-change studies in the Maya area. Ancient Mesoamerica, 13(01), 79-84. [2] Yaeger, J., Hodell, D. A., 2008. The collapse of Maya civilization: assessing the interaction of culture, climate, and environment. El Niño, Catastrophism, and Culture Change in Ancient America, 197-251. [3] Hodell, D. A., Curtis, J. H., Brenner, M., 1995. Possible role of climate in the collapse of Classic Maya civilization. Nature, 375(6530), 391-394. [4] Aimers, J., Hodell, D., 2011. Societal collapse: Drought and the Maya. Nature 479(7371), 44-45 (2011). [5] Medina-Elizalde, M., Rohling, E. J., 2012. Collapse of Classic Maya civilization related to modest reduction

  5. Summary of Time Period-Based and Other Approximation Methods for Determining the Capacity Value of Wind and Solar in the United States: September 2010 - February 2012

    SciTech Connect

    Rogers, J.; Porter, K.

    2012-03-01

    This paper updates previous work that describes time period-based and other approximation methods for estimating the capacity value of wind power and extends it to include solar power. The paper summarizes various methods presented in utility integrated resource plans, regional transmission organization methodologies, regional stakeholder initiatives, regulatory proceedings, and academic and industry studies. Time period-based approximation methods typically measure the contribution of a wind or solar plant at the time of system peak - sometimes over a period of months or the average of multiple years.

  6. Projection of landfill stabilization period by time series analysis of leachate quality and transformation trends of VOCs.

    PubMed

    Sizirici, Banu; Tansel, Berrin

    2010-01-01

    The purpose of this study was to evaluate suitability of using the time series analysis for selected leachate quantity and quality parameters to forecast the duration of post closure period of a closed landfill. Selected leachate quality parameters (i.e., sodium, chloride, iron, bicarbonate, total dissolved solids (TDS), and ammonium as N) and volatile organic compounds (VOCs) (i.e., vinyl chloride, 1,4-dichlorobenzene, chlorobenzene, benzene, toluene, ethyl benzene, xylenes, total BTEX) were analyzed by the time series multiplicative decomposition model to estimate the projected levels of the parameters. These parameters were selected based on their detection levels and consistency of detection in leachate samples. In addition, VOCs detected in leachate and their chemical transformations were considered in view of the decomposition stage of the landfill. Projected leachate quality trends were analyzed and compared with the maximum contaminant level (MCL) for the respective parameters. Conditions that lead to specific trends (i.e., increasing, decreasing, or steady) and interactions of leachate quality parameters were evaluated. Decreasing trends were projected for leachate quantity, concentrations of sodium, chloride, TDS, ammonia as N, vinyl chloride, 1,4-dichlorobenzene, benzene, toluene, ethyl benzene, xylenes, and total BTEX. Increasing trends were projected for concentrations of iron, bicarbonate, and chlorobenzene. Anaerobic conditions in landfill provide favorable conditions for corrosion of iron resulting in higher concentrations over time. Bicarbonate formation as a byproduct of bacterial respiration during waste decomposition and the lime rock cap system of the landfill contribute to the increasing levels of bicarbonate in leachate. Chlorobenzene is produced during anaerobic biodegradation of 1,4-dichlorobenzene, hence, the increasing trend of chlorobenzene may be due to the declining trend of 1,4-dichlorobenzene. The time series multiplicative

  7. Media use by children younger than 2 years.

    PubMed

    Brown, Ari

    2011-11-01

    In 1999, the American Academy of Pediatrics (AAP) issued a policy statement addressing media use in children. The purpose of that statement was to educate parents about the effects that media--both the amount and the content--may have on children. In one part of that statement, the AAP recommended that "pediatricians should urge parents to avoid television viewing for children under the age of two years." The wording of the policy specifically discouraged media use in this age group, although it is frequently misquoted by media outlets as no media exposure in this age group. The AAP believed that there were significantly more potential negative effects of media than positive ones for this age group and, thus, advised families to thoughtfully consider media use for infants. This policy statement reaffirms the 1999 statement with respect to media use in infants and children younger than 2 years and provides updated research findings to support it. This statement addresses (1) the lack of evidence supporting educational or developmental benefits for media use by children younger than 2 years, (2) the potential adverse health and developmental effects of media use by children younger than 2 years, and (3) adverse effects of parental media use (background media) on children younger than 2 years.

  8. Early Intervention for Children Birth Through 2 Years.

    ERIC Educational Resources Information Center

    Wetherby, Catherine, Ed.

    1988-01-01

    Information is provided for parents of handicapped children, aged 0-2 years, on the uniqueness of each infant's learning processes and the valuable role that parents and others can play in helping their infants with special needs to make the most of their abilities. The digest examines parents' concerns during the infant's hospital stay and early…

  9. Minoxidil induced hypertrichosis in a 2 year-old child.

    PubMed

    Herskovitz, Ingrid; Freedman, Joshua; Tosti, Antonella

    2013-01-01

    We report a case of a 2 year-old male patient who developed generalized hypertrichosis after 2 months of treatment with 5% minoxidil foam for alopecia areata. This report highlights the danger of prescribing  topical minoxidil to young children and the need to correctly instruct caretakers about its administration. PMID:24555107

  10. Repetitive Behaviours in Typically Developing 2-Year-Olds

    ERIC Educational Resources Information Center

    Leekam, Susan; Tandos, Jonathan; McConachie, Helen; Meins, Elizabeth; Parkinson, Kathryn; Wright, Charlotte; Turner, Michelle; Arnott, Bronia; Vittorini, Lucia; Le Couteur, Ann

    2007-01-01

    Background: Repetitive behaviours are an essential part of the diagnosis of autism but are also commonly seen in typically developing children. The current study investigated the frequency and factor structure of repetitive behaviours in a large community sample of 2-year-olds. Methods: A new measure, the Repetitive Behaviour Questionnaire (RBQ-2)…

  11. Ornamental Horticulture Technology; Suggested 2-Year Post High School Curriculums.

    ERIC Educational Resources Information Center

    Bureau of Adult, Vocational, and Technical Education (DHEW/OE), Washington, DC. Div. of Vocational and Technical Education.

    Developed by a technical education specialist, this guide is designed to aid school administrators in planning and developing 2-year post-high school programs or evaluating existing programs in ornamental horticulture technology. In addition to general information on the program, contents include course outlines with examples of tests and…

  12. Breast Cancer-Specific Mortality Pattern and Its Changing Feature According to Estrogen Receptor Status in Two Time Periods

    PubMed Central

    Jiang, Yizhou; Shao, Zhimin

    2016-01-01

    Purpose To determine whether and how the patterns of breast cancer-specific mortality (BCSM) changed along with time periods. Methods We used the Surveillance, Epidemiology and End Results registry to identify 228209 female patients diagnosed with invasive breast cancer between 1990 and 2000 (cohort 1 [C1], 112981) and between 2001 and 2005 (cohort 2 [C2], 115228). BCSM was compared in two cohorts using Cox proportional hazard regression models. We analysed the relative hazard ratios (HRs) and absolute BCSM rates by flexible parametric survival modelling. Results The patterns of BCSM were similar between the two cohorts, with the peak of mortality presenting in the first 2–3 years after diagnosis, and mortality rate significantly decreased in C2 in all cases. In C2, the annual BCSM rate of all cases was 9.64 (per 1000 persons per year) in year 10 with a peak rate of 23.34 in year 2. In ER-negative and high-risk patients, marked survival improvements were achieved mostly in the first 5 years, while in ER-positive and low-risk patients, survival improvements were less but constant up to 10 years. Conclusion There has been a significant improvement of BCSM with substantially decreased mortality within 5 years. The current pattern of BCSM and its changing feature differs according to ER status. Our findings have some clinical implications both for treatment decisions and adjuvant treatment trial design. PMID:27299729

  13. Associations Between Income Inequality and Mortality Among US States: The Importance of Time Period and Source of Income Data

    PubMed Central

    Lynch, John; Harper, Sam; Kaplan, George A.; Davey Smith, George

    2005-01-01

    Objectives. We used census data to examine associations between income inequality and mortality among US states for each decade from 1949 to 1999 and tax return income data to estimate associations for 1989. Methods. Cross-sectional correlation analyses were used to assess income inequality–mortality relationships. Results. Census income analyses revealed little association between income inequality and mortality for 1949, 1959, or 1969. An association emerged for 1979 and strengthened for 1989 but weakened for 1999. When income inequality was based on tax return data, associations were weaker for both 1989 and 1999. Conclusions. The strong association between income inequality and mortality observed among US states for 1989 was not observed for other periods from 1949 through 1999. In addition, when tax return rather than census data were used, the association was weaker for 1989 and 1999. The potential for distal social determinants of population health (e.g., income inequality) to affect mortality is contingent on how such determinants influence levels of proximal risk factors and the time lags between exposure to those risk factors and effects on specific health outcomes. PMID:16006417

  14. Quantum 3D spin-glass system on the scales of space-time periods of external electromagnetic fields

    SciTech Connect

    Gevorkyan, A. S.

    2012-10-15

    A dielectric medium consisting of rigidly polarized molecules has been treated as a quantum 3D disordered spin system. It is shown that using Birkhoff's ergodic hypothesis the initial 3D disordered spin problem on scales of space-time periods of external field is reduced to two conditionally separable 1D problems. The first problem describes a 1D disordered N-particle quantum system with relaxation in random environment while the second one describes statistical properties of ensemble of disordered 1D steric spin chains of certain length. Basing on constructions which are developed in both problems, the coefficient of polarizability related to collective orientational effects under the influence of external field was calculated. On the basis of these investigations the equation of Clausius-Mossotti (CM) has been generalized as well as the equation for permittivity. It is shown that under the influence of weak standing electromagnetic fields in the equation of CM arising of catastrophe is possible, that can substantially change behavior of permittivity in the X-ray region on the macroscopic scale of space.

  15. Inter-hemispheric coupling during northern polar summer periods of 2002-2010 using TIMED/SABER measurements

    NASA Astrophysics Data System (ADS)

    Goldberg, R. A.; Feofilov, A. G.; Pesnell, W. D.; Kutepov, A. A.

    2013-11-01

    It has been found that for more than one polar summer season between 2002 and 2010, the northern polar mesospheric region near and above about 80 km was warmer than normal. The strongest warming effect of this type was observed to occur during northern summer 2002. Observational and theoretical studies imply that these “anomalies” were preceded by unusual dynamical processes in the southern hemisphere. We have analyzed temperature distributions measured by the SABER limb scanning infrared radiometer aboard the NASA TIMED satellite between 2002 and 2010 at altitudes from 15 to 110 km and for latitudes between 83°S and 83°N. We describe the approach to trace the spatial extent of inter-hemispheric temperature correlations demonstrating the global features that were unique for the “anomalous” northern polar summers. From our analysis of SABER data from 2002 to 2010, the anomalous heating for the northern mesopause region during northern summer was accompanied by stratospheric heating in the equatorial region. In the winter hemisphere it is accompanied by heating in the lower stratosphere and mesopause region, and cooling in the stratopause region. Also, all the elements of the temperature anomaly structure appear to develop and fade away nearly simultaneously, thereby suggesting either a global influence or a short lagging period (less than 7 days).

  16. Differences in maternal behavior and development of their pups depend on the time of methamphetamine exposure during gestation period.

    PubMed

    Malinová-Ševčíková, M; Hrebíčková, I; Macúchová, E; Nová, E; Pometlová, M; Šlamberová, R

    2014-01-01

    The present study examined the hypothesis that the extension of noxious effect of methamphetamine (MA) on maternal behavior and postnatal development on the pups may differ in dependence with time of application. Female rats were injected with MA (5 mg/kg) or saline during first (embryonic day (ED) 1-11) or second (ED 12-22) half of gestation. Our results demonstrated that MA exposure on ED 12-22 led to decreased birth weight and weight gained during lactation period relative to rats treated on ED 1-11. Both sexes treated prenatally with MA on ED 1-11 opened eyes earlier compared to animals treated on ED 12-22. As a matter of sensorimotor development application of MA on ED 1-11 impaired the righting reflex, while MA exposure on ED 12-22 impaired the performance of beam balance test in male rats. There were no differences in maternal behavior. Therefore, it seems that MA exposure in the first half of the gestation impaired the early sensorimotor development that is under control of the brain stem, while the MA exposure in the second half of gestation affected the beam balance performance that is dependent on the function of the cerebellum.

  17. Quasi-periodic Oscillations Associated with Spectral Branches in Rossi X-Ray Timing Explorer Observations of Circinus X-1

    NASA Astrophysics Data System (ADS)

    Shirey, Robert E.; Bradt, Hale V.; Levine, Alan M.; Morgan, Edward H.

    1998-10-01

    We present Rossi X-Ray Timing Explorer (RXTE) All-Sky Monitor observations of the X-ray binary Circinus X-1 that illustrate the variety of intensity profiles associated with the 16.55 day flaring cycle of the source. We also present eight observations of Cir X-1 made with the RXTE Proportional Counter Array over the course of a cycle wherein the average intensity of the flaring state decreased gradually over ~12 days. Fourier power density spectra for these observations show a narrow quasi-periodic oscillation (QPO) peak that shifts in frequency between 6.8 and 32 Hz, as well as a broad QPO peak that remains roughly stationary at ~4 Hz. We identify these as Z-source horizontal and normal branch oscillations (HBOs/NBOs), respectively. Color-color and hardness-intensity diagrams (CDs/HIDs) show curvilinear tracks for each of the observations. The properties of the QPOs and very low frequency noise allow us to identify segments of these tracks with Z-source horizontal, normal, and flaring branches that shift location in the CDs and HIDs over the course of the 16.55 day cycle. These results contradict a previous prediction, based on the hypothesis that Cir X-1 is a high-Ṁ atoll source, that HBOs should never occur in this source.

  18. 3D imaging of cone photoreceptors over extended time periods using optical coherence tomography with adaptive optics

    NASA Astrophysics Data System (ADS)

    Kocaoglu, Omer P.; Lee, Sangyeol; Jonnal, Ravi S.; Wang, Qiang; Herde, Ashley E.; Besecker, Jason; Gao, Weihua; Miller, Donald T.

    2011-03-01

    Optical coherence tomography with adaptive optics (AO-OCT) is a highly sensitive, noninvasive method for 3D imaging of the microscopic retina. The purpose of this study is to advance AO-OCT technology by enabling repeated imaging of cone photoreceptors over extended periods of time (days). This sort of longitudinal imaging permits monitoring of 3D cone dynamics in both normal and diseased eyes, in particular the physiological processes of disc renewal and phagocytosis, which are disrupted by retinal diseases such as age related macular degeneration and retinitis pigmentosa. For this study, the existing AO-OCT system at Indiana underwent several major hardware and software improvements to optimize system performance for 4D cone imaging. First, ultrahigh speed imaging was realized using a Basler Sprint camera. Second, a light source with adjustable spectrum was realized by integration of an Integral laser (Femto Lasers, λc=800nm, ▵λ=160nm) and spectral filters in the source arm. For cone imaging, we used a bandpass filter with λc=809nm and ▵λ=81nm (2.6 μm nominal axial resolution in tissue, and 167 KHz A-line rate using 1,408 px), which reduced the impact of eye motion compared to previous AO-OCT implementations. Third, eye motion artifacts were further reduced by custom ImageJ plugins that registered (axially and laterally) the volume videos. In two subjects, cone photoreceptors were imaged and tracked over a ten day period and their reflectance and outer segment (OS) lengths measured. High-speed imaging and image registration/dewarping were found to reduce eye motion to a fraction of a cone width (1 μm root mean square). The pattern of reflections in the cones was found to change dramatically and occurred on a spatial scale well below the resolution of clinical instruments. Normalized reflectance of connecting cilia (CC) and OS posterior tip (PT) of an exemplary cone was 54+/-4, 47+/-4, 48+/-6, 50+/-5, 56+/-1% and 46+/-4, 53+/-4, 52+/-6, 50+/-5, 44

  19. 31 CFR 256.33 - For what period of time is interest computed under 31 U.S.C. 1304(b)?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false For what period of time is interest computed under 31 U.S.C. 1304(b)? 256.33 Section 256.33 Money and Finance: Treasury Regulations Relating to....33 For what period of time is interest computed under 31 U.S.C. 1304(b)? Interest is computed...

  20. 31 CFR 256.33 - For what period of time is interest computed under 31 U.S.C. 1304(b)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false For what period of time is interest computed under 31 U.S.C. 1304(b)? 256.33 Section 256.33 Money and Finance: Treasury Regulations Relating to....33 For what period of time is interest computed under 31 U.S.C. 1304(b)? Interest is computed...

  1. Increased Food Insecurity Among Mothers of 2 Year Olds with Special Health Care Needs.

    PubMed

    Adams, Elizabeth J; Hoffmann, Laurel M; Rosenberg, Kenneth D; Peters, Dawn; Pennise, Melissa

    2015-10-01

    The objective of this study is to explore the association between having a child with special health care needs (CSHCN) and food insecurity when the child is 2 years old. We studied women who had a live birth in 2004-2005 and responded to Oregon's Pregnancy Risk Assessment Monitoring System (PRAMS) survey 3 months postpartum (Time 1) and the follow-up survey (PRAMS-2), when the child was 2 years old (Time 2). Women answering affirmatively to the PRAMS-2 question, "In the last 12 months, did you ever eat less than you felt you should because there was not enough money for food?" were considered food insecure. CSHCN status was identified by affirmative responses to questions about needs for ongoing services (Time 2). PRAMS and PRAMS-2 responses were weighted for study design and non-response. Results report weighted analyses, unless noted. Among 1812 mothers completing PRAMS-2, 13.6 % (unweighted) had a 2-year-old CSHCN and 11.9 % (unweighted) were food insecure at Time 2. The estimated prevalence of food insecurity at 2-year follow-up was 20.7 % among families of CSHCN and 9.7 % for others. After adjustment for Time 2 marital status, education, lifetime U.S. residence, income and health conditions, multivariable logistic regression revealed that odds of food insecurity were more than two times as great for CSHCN mothers 2 years post-partum compared to non-CSHCN mothers (adjusted odds ratio 2.6, 95 % confidence interval 1.3, 4.6). Families of CSHCN face increased risk for food insecurity. Improved understanding of causal determinants of food insecurity among households of CSHCN is needed.

  2. The effects of early headgear treatment on dental arches and craniofacial morphology: a report of a 2 year randomized study.

    PubMed

    Mäntysaari, Raimo; Kantomaa, Tuomo; Pirttiniemi, Pertti; Pykäläinen, Aila

    2004-02-01

    The aim of the present study was to determine the effects of early headgear treatment on dental arches and craniofacial morphology in children in the early mixed dentition. The total study group comprised 68 children of both sexes (40 boys and 28 girls) aged 7.6 years [standard deviation (SD) 0.3]. The children, who had a Class II tendency in occlusion and moderate crowding of the dental arches, were randomly divided into two groups of equal size, matched according to gender. In the headgear (HG) group, treatment was initiated immediately. The mean treatment time was 16 months. In the second group, which served as the control, only interceptive procedures were performed during the follow-up period. The records, which included dental casts and lateral cephalograms, were obtained after follow-up periods of 1 and 2 years. The lengths and the widths of the maxillary and mandibular dental arches were significantly increased in the HG group after the 2 year follow-up period. The mean increase in lower arch length and width was 2.4 mm (SD 1.7) and 2.2 mm (SD 1.2), respectively. On average, the space gain in the lower arch was half that of the upper arch. No significant changes were found in the arch dimensions of the control group. Maxillary growth restraint and labial tilting of the incisors were the most significant cephalometric findings in the HG group when compared with the controls. The use of headgear in the early mixed dentition is effective in the treatment of moderate crowding. It is noteworthy that significant space gain in the dimensions of the lower arch can be achieved by headgear application to the upper first molars.

  3. Analysis of global O(t(-α)) stability and global asymptotical periodicity for a class of fractional-order complex-valued neural networks with time varying delays.

    PubMed

    Rakkiyappan, R; Sivaranjani, R; Velmurugan, G; Cao, Jinde

    2016-05-01

    In this paper, the problem of the global O(t(-α)) stability and global asymptotic periodicity for a class of fractional-order complex-valued neural networks (FCVNNs) with time varying delays is investigated. By constructing suitable Lyapunov functionals and a Leibniz rule for fractional differentiation, some new sufficient conditions are established to ensure that the addressed FCVNNs are globally O(t(-α)) stable. Moreover, some sufficient conditions for the global asymptotic periodicity of the addressed FCVNNs with time varying delays are derived, showing that all solutions converge to the same periodic function. Finally, numerical examples are given to demonstrate the effectiveness and usefulness of our theoretical results.

  4. Myopia Control with a Novel Peripheral Gradient Soft Lens and Orthokeratology: A 2-Year Clinical Trial

    PubMed Central

    Pauné, Jaime; Morales, Hari; Armengol, Jesús; Quevedo, Lluisa; Faria-Ribeiro, Miguel; González-Méijome, José M.

    2015-01-01

    Objective. To evaluate the degree of axial elongation with soft radial refractive gradient (SRRG) contact lenses, orthokeratology (OK), and single vision (SV) spectacle lenses (control) during a period of 1 year before treatment and 2 years after treatment. Methods. This was a prospective, longitudinal, nonrandomized study. The study groups consisted of 30, 29, and 41 children, respectively. The axial length (AL) was measured during 2 years after recruitment and lens fitting. Results. The baseline refractive sphere was correlated significantly (Spearman's Rho (ρ) correlation = 0.542; P < 0.0001) with the amount of myopia progression before baseline. After 2 years, the mean myopia progression values for the SRRG, OK, and SV groups were −0.56 ± 0.51, −0.32 ± 0.53, and −0.98 ± 0.58 diopter, respectively. The results represent reductions in myopic progression of 43% and 67% for the SRRG and OK groups, respectively, compared to the SV group. The AL increased 27% and 38% less in the SRRG and OK groups, respectively compared with the SV group at the 2-year visit (P < 0.05). Axial elongation was not significantly different between SRRG and OK (P = 0.430). Conclusion. The SRRG lens significantly decreased AL elongation compared to the SV control group. The SRRG lens was similarly effective to OK in preventing myopia progression in myopic children and adolescent. PMID:26605331

  5. 20 CFR 663.530 - Is there a time limit on the period of initial eligibility for training providers?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... eligible providers whose determination of initial eligibility occurs within six months of the date of..., initial eligibility may be extended for a period of up to six additional months, if the...

  6. 20 CFR 663.530 - Is there a time limit on the period of initial eligibility for training providers?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... eligible providers whose determination of initial eligibility occurs within six months of the date of..., initial eligibility may be extended for a period of up to six additional months, if the...

  7. Comparison of Patients with Parkinson's Disease or Cerebellar Lesions in the Production of Periodic Movements Involving Event-Based or Emergent Timing

    ERIC Educational Resources Information Center

    Spencer, R.M.C.; Ivry, R.B.

    2005-01-01

    We have hypothesized a distinction between the processes required to control the timing of different classes of periodic movements. In one class, salient events mark successive cycles. For these movements, we hypothesize that the temporal goal is a requisite component of the task representation, what we refer to as event-based timing. In the other…

  8. AN EXTENDED AND MORE SENSITIVE SEARCH FOR PERIODICITIES IN ROSSI X-RAY TIMING EXPLORER/ALL-SKY MONITOR X-RAY LIGHT CURVES

    SciTech Connect

    Levine, Alan M.; Bradt, Hale V.; Chakrabarty, Deepto; Corbet, Robin H. D.; Harris, Robert J. E-mail: hale@space.mit.edu E-mail: robin.corbet@nasa.gov

    2011-09-01

    We present the results of a systematic search in {approx}14 years of Rossi X-ray Timing Explorer All-Sky Monitor (ASM) data for evidence of periodicities. Two variations of the commonly used Fourier analysis search method have been employed to significantly improve upon the sensitivity achieved by Wen et al. in 2006, who also searched for periodicities in ASM data. In addition, the present search is comprehensive in terms of sources studied and frequency range covered, and has yielded the detection of the signatures of the orbital periods of eight low-mass X-ray binary systems and of ten high-mass X-ray binaries not listed in the tables of Wen et al. Orbital periods, epochs, signal amplitudes, modulation fractions, and folded light curves are given for each of these systems. Seven of the orbital periods are the most precise reported to date. In the course of this work, the 18.545 day orbital period of IGR J18483-0311 was co-discovered, and the first detections in X-rays were made of the {approx}3.9 day orbital period of LMC X-1 and the {approx}3.79 hr orbital period of 4U 1636-536. The results inform future searches for orbital and other periodicities in X-ray binaries.

  9. Maternal Affective Illness in the Perinatal Period and Child Development: Findings on Developmental Timing, Mechanisms, and Intervention.

    PubMed

    O'Connor, Thomas G; Monk, Catherine; Burke, Anne S

    2016-03-01

    Maternal mental illness is one of the most reliable risks for clinically significant child adjustment difficulties. The research literature in this area is very large and broad and dates back decades. In this review, we consider recent research findings on maternal mental illness and child development by focusing particularly on affective illness the perinatal period. We do this because maternal affective illness in the perinatal period is common; recent evidence suggests that pre- and postpartum maternal depression may have lasting effects on child behavioral and somatic health; research in the perinatal period raises acute and compelling questions about mechanisms of transmission and effect; and perinatal-focused interventions may offer distinct advantages for benefitting mother and child and gaining insights into developmental mechanisms. Throughout the review, we attend to the increasing integration of psychological and biological models and the trans-disciplinary approach now required for clinical investigation.

  10. Clinical outcomes of pars plicata anterior vitrectomy: 2-year results

    PubMed Central

    Narang, Priya; Agarwal, Amar

    2015-01-01

    Purpose: To demonstrate the safety and outcome of a surgical approach that uses pars plicata site for anterior vitrectomy during phacoemulsification procedure complicated by posterior capsule rupture and residual cortical matter. Design: Single center, retrospective, interventional, noncomparative study. Materials and Methods: Medical records of a consecutive series of 35 eyes of 35 patients who underwent pars plicata anterior vitrectomy (PPAV) were reviewed. The main outcome measures were corrected and uncorrected distance visual acuity (CDVA, UDVA), early and late postoperative complications and intraocular pressure (IOP). Ultrasound biomicroscopic (UBM) evaluation of sclerotomy site and spectral domain optical coherence tomography analysis for central macular thickness (CMT) was performed. The final visual outcome at 2 years was evaluated. Results: At 2 years follow-up, the mean postoperative UDVA (logarithm of the minimum angle of resolution [logMAR]) and CDVA (logMAR) was 0.49 ± 0.26 and 0.19 ± 0.14, respectively. There was no significant change in the IOP (P = 0.061) and the mean CMT at 2 years was 192.5 ± 5.54 μm. The postoperative UBM image of the sclerotomy site at 8 weeks demonstrated a clear wound without any vitreous adhesion or incarceration. Intraoperative hyphema was seen in 1 (2.8%) case and postoperative uveitis was seen in 2 (5.7%) cases, which resolved with medications. No case of an iatrogenic retinal break or retinal detachment was reported. Conclusions: PPAV enables a closed chamber approach, allows thorough cleanup of vitreous in the pupillary plane and anterior chamber and affords better access to the subincisional and retropupillary cortical remnant with a significant visual outcome and an acceptable complication rate. PMID:26632124

  11. Borderline personality disorder features predict negative outcomes 2 years later.

    PubMed

    Bagge, Courtney; Nickell, Angela; Stepp, Stephanie; Durrett, Christine; Jackson, Kristina; Trull, Timothy J

    2004-05-01

    In a sample of 351 young adults, the authors assessed whether borderline personality disorder (BPD) features prospectively predicted negative outcomes (poorer academic achievement and social maladjustment) over the subsequent 2 years, over and above gender and both Axis I and Axis II psychopathology. Borderline traits were significantly related to these outcomes, with impulsivity and affective instability the most highly associated. The present findings suggest that the impulsivity and affective instability associated with BPD leads to impairment in relating well with others, in meeting social role obligations, and in academic or occupational achievement. Therefore, these may be especially important features to target in interventions for BPD.

  12. Global O(t(-α)) stability and global asymptotical periodicity for a non-autonomous fractional-order neural networks with time-varying delays.

    PubMed

    Chen, Boshan; Chen, Jiejie

    2016-01-01

    The present paper studies global O(t(-α)) stability and global asymptotical periodicity for a non-autonomous fractional-order neural networks with time-varying delays (FDNN). Firstly, some sufficient conditions are established to ensure that a non-autonomous FDNN is global O(t(-α)) stable based on a new Lyapunov function method and Leibniz rule for fractional differentiation. Next it is shown that the periodic or autonomous FDNN cannot generate exactly nonconstant periodic solution under any circumstances. Finally, we show that all solutions converge to a same periodic function for a periodic FDNN by using a fractional-order differential inequality technique. Our issues, methods and results are all new.

  13. Cyclic period changes and the light-time effect in eclipsing binaries: A low-mass companion around the system VV Ursae Majoris

    NASA Astrophysics Data System (ADS)

    Tanrıver, Mehmet

    2015-04-01

    In this article, a period analysis of the late-type eclipsing binary VV UMa is presented. This work is based on the periodic variation of eclipse timings of the VV UMa binary. We determined the orbital properties and mass of a third orbiting body in the system by analyzing the light-travel time effect. The O-C diagram constructed for all available minima times of VV UMa exhibits a cyclic character superimposed on a linear variation. This variation includes three maxima and two minima within approximately 28,240 orbital periods of the system, which can be explained as the light-travel time effect (LITE) because of an unseen third body in a triple system that causes variations of the eclipse arrival times. New parameter values of the light-time travel effect because of the third body were computed with a period of 23.22 ± 0.17 years in the system. The cyclic-variation analysis produces a value of 0.0139 day as the semi-amplitude of the light-travel time effect and 0.35 as the orbital eccentricity of the third body. The mass of the third body that orbits the eclipsing binary stars is 0.787 ± 0.02 M⊙, and the semi-major axis of its orbit is 10.75 AU.

  14. Primed acclimation of cultivated peanut (Arachis hypogaea L.) through the use of deficit irrigation timed to crop developmental periods

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Water-deficits and high temperatures are the predominant factors limiting peanut production across the U.S., either because of regional aridity or untimely rainfall events during crucial crop developmental periods. In the southern High Plains of west Texas and eastern New Mexico, low average annual ...

  15. MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex.

    PubMed

    Krishnan, Keerthi; Wang, Bor-Shuen; Lu, Jiangteng; Wang, Lang; Maffei, Arianna; Cang, Jianhua; Huang, Z Josh

    2015-08-25

    Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome, an autism spectrum-associated disorder with a host of neurological and sensory symptoms, but the pathogenic mechanisms remain elusive. Neuronal circuits are shaped by experience during critical periods of heightened plasticity. The maturation of cortical GABA inhibitory circuitry, the parvalbumin(+) (PV(+)) fast-spiking interneurons in particular, is a key component that regulates the initiation and termination of the critical period. Using MeCP2-null mice, we examined experience-dependent development of neural circuits in the primary visual cortex. The functional maturation of parvalbumin interneurons was accelerated upon vision onset, as indicated by elevated GABA synthetic enzymes, vesicular GABA transporter, perineuronal nets, and enhanced GABA transmission among PV interneurons. These changes correlated with a precocious onset and closure of critical period and deficient binocular visual function in mature animals. Reduction of GAD67 expression rescued the precocious opening of the critical period, suggesting its major role in MECP2-mediated regulation of experience-driven circuit development. Our results identify molecular changes in a defined cortical cell type and link aberrant developmental trajectory to functional deficits in a model of neuropsychiatric disorder.

  16. Are Transition Periods the Optimal Time for Acceleration? The Training of a First Order Conservation in Young Children.

    ERIC Educational Resources Information Center

    Biskin, Donald S.; Rice, Deborah

    The effectiveness of acceleration training with children who were in a transition period was examined. Forty-eight kindergarten children were separated into four groups on the basis of their status (Preoperational vs. Transitional) and whether or not they received three sessions of inversion-negation training. The results of the immediate and…

  17. MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex

    PubMed Central

    Krishnan, Keerthi; Wang, Bor-Shuen; Lu, Jiangteng; Wang, Lang; Maffei, Arianna; Cang, Jianhua; Huang, Z. Josh

    2015-01-01

    Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome, an autism spectrum-associated disorder with a host of neurological and sensory symptoms, but the pathogenic mechanisms remain elusive. Neuronal circuits are shaped by experience during critical periods of heightened plasticity. The maturation of cortical GABA inhibitory circuitry, the parvalbumin+ (PV+) fast-spiking interneurons in particular, is a key component that regulates the initiation and termination of the critical period. Using MeCP2-null mice, we examined experience-dependent development of neural circuits in the primary visual cortex. The functional maturation of parvalbumin interneurons was accelerated upon vision onset, as indicated by elevated GABA synthetic enzymes, vesicular GABA transporter, perineuronal nets, and enhanced GABA transmission among PV interneurons. These changes correlated with a precocious onset and closure of critical period and deficient binocular visual function in mature animals. Reduction of GAD67 expression rescued the precocious opening of the critical period, suggesting its major role in MECP2-mediated regulation of experience-driven circuit development. Our results identify molecular changes in a defined cortical cell type and link aberrant developmental trajectory to functional deficits in a model of neuropsychiatric disorder. PMID:26261347

  18. 41 CFR 302-2.10 - Does the 1-year time period in § 302-2.8 include time that I cannot travel and/or transport my...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false Does the 1-year time period in § 302-2.8 include time that I cannot travel and/or transport my household effects due to... time that I cannot travel and/or transport my household effects due to shipping restrictions to or...

  19. 41 CFR 302-2.10 - Does the 1-year time period in § 302-2.8 include time that I cannot travel and/or transport my...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false Does the 1-year time period in § 302-2.8 include time that I cannot travel and/or transport my household effects due to... time that I cannot travel and/or transport my household effects due to shipping restrictions to or...

  20. 41 CFR 302-2.10 - Does the 1-year time period in § 302-2.8 include time that I cannot travel and/or transport my...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true Does the 1-year time period in § 302-2.8 include time that I cannot travel and/or transport my household effects due to... time that I cannot travel and/or transport my household effects due to shipping restrictions to or...

  1. Dynamics of difenoconazole and propiconazole residues on pomegranate over 2 years under field conditions.

    PubMed

    Mohapatra, Soudamini

    2016-03-01

    Residue dynamics of difenoconazole and propiconazole on pomegranate was studied after application at the recommended and double doses of 125 and 250 g active ingredient (a.i.) ha(-1) during August-October 2012. The study was repeated during the same period in 2013. QuEChERS method, in conjunction with gas chromatography (GC), was used for analysis of the fungicides after carrying out the method validation. The recoveries of the fungicides from pomegranate and soil were between 80.3 and 96.2 %; the limit of detection (LOD) and limit of quantification (LOQ) were 0.016 and 0.05 mg kg(-1), respectively. The uncertainties of measurement were between 9.7 and 16.3 %. The initial residue deposits of difenoconazole were 0.875 and 1.205 mg kg(-1) from treatment at the recommended dose and 1.54 and 1.672 mg kg(-1) from treatment at the double dose from the first- and second-year studies. Propiconazole residues were 0.663 and 0.864 mg kg(-1) from recommended dose treatments and 1.474 and 2.045 mg kg(-1) from double dose treatments from the first- and second-year studies. The half-lives of degradation of difenoconazole were 6.4-8.4 days and propiconazole 7.9-8.5 days over the 2 years. Residues of difenoconazole and propiconazole remained on the pomegranate fruit surface and did not move to the edible part (aril). The pre-harvest intervals (PHIs), the time required for the residues to reduce below their respective EU maximum residue limits (MRLs), were 25.4 and 30.8 days for difenoconazole and 33.3 and 43.8 days for propiconazole from treatments at the recommended and double doses, respectively. Keeping in view consumer safety, the longer PHI from the two studies has been selected.

  2. Progression of fibromyalgia: results from a 2-year observational fibromyalgia and chronic pain study in the US

    PubMed Central

    Adams, Edgar H; McElroy, Heather J; Udall, Margarita; Masters, Elizabeth T; Mann, Rachael M; Schaefer, Caroline P; Cappelleri, Joseph C; Clair, Andrew G; Hopps, Markay; Daniel, Shoshana R; Mease, Philip; Silverman, Stuart L; Staud, Roland

    2016-01-01

    Background A previous fibromyalgia (FM) research reports that 20%–47% of diagnosed patients may not meet the study definition of FM 1–2 years after diagnosis. The aim of this study was to gain a better understanding of the progression of FM in a geographically diverse cohort over a 2-year time period. Methods This cohort study followed 226 subjects recruited online to assess FM and chronic widespread pain (CWP) diagnosis stability over time. At enrollment (baseline), subjects provided informed consent, completed an online questionnaire consisting of the London Fibromyalgia Epidemiology Study Screening Questionnaire to screen for CWP (bilateral pain above/below waist lasting ≥1 week in the past 3 months), visited a site for physician evaluation for FM, and completed a questionnaire with validated patient-reported outcome instruments. Subjects were classified into mutually exclusive groups: FM+CWP+ (screened positive for CWP and received physician diagnosis of FM), FM−CWP+ (screened positive for CWP but did not receive physician diagnosis of FM), and FM−CWP− (screened negative for CWP). Approximately 2 years later (follow-up), subjects were reassessed at the same study site and completed a questionnaire with the same patient-reported outcomes. Results Seventy-six FM+CWP+ subjects completed assessments at both time points; 56 (73.7%) met the FM study definition at follow-up. Twenty subjects no longer met the FM study definition (eleven became FM−CWP− and nine became FM−CWP+). Ten subjects (two from FM−CWP− and eight from FM−CWP+) transitioned into the FM+CWP+ group at follow-up; they reported more tender points and pain interference with sleep and worse physical function at baseline compared with subjects who did not transition to FM+CWP+. Most (76.7%) of the subjects who transitioned into/out of FM+CWP+ experienced changes in CWP, number of positive tender points, or both. Conclusion The results suggest that some FM+CWP+ patients experience

  3. Extension of the spectral element method for stability analysis of time-periodic delay-differential equations with multiple and distributed delays

    NASA Astrophysics Data System (ADS)

    Lehotzky, David; Insperger, Tamas; Stepan, Gabor

    2016-06-01

    The spectral element method was introduced by Khasawneh and Mann (2013) for the stability analysis of time-periodic delay-differential equations (DDEs) with multiple delays. In this paper, this method is generalized for time-periodic DDEs with multiple delays and distributed delay. For this general case, an explicit formula is given for the construction of the matrix approximation of the monodromy operator. The derived formula enables the algorithmic application of the method to DDEs with general combinations of delays for arbitrary point sets and test functions. Stability analysis is demonstrated for specific case studies, and the computation code is provided for a complex example.

  4. Role Modeling in the First 2 Years of Medical School.

    PubMed

    Obadia, Sharon J

    2015-08-01

    Role modeling opportunities for osteopathic physician teachers during a student's first 2 years of medical school are emerging as more colleges of osteopathic medicine strive to connect basic science didactics with clinically based learning activities. Examples of positive modeling by physician teachers during the first years of medical school are illustrated by 10 vignettes that can be incorporated into faculty development programs to increase awareness of such opportunities. The physician teacher in each vignette interacts with the student demonstrating desired professional behaviors. These vignettes also illustrate the effect of a positive "hidden curriculum" on a student's professional development. By recognizing these valuable teachable moments, teachers can incorporate role modeling into their daily practice. PMID:26214824

  5. Child-directed action promotes 2-year-olds' imitation.

    PubMed

    Williamson, Rebecca A; Brand, Rebecca J

    2014-02-01

    Children are voracious learners and adults are ubiquitous teachers. This project investigated whether the special infant-directed action modifications parents use when teaching their children (called "motionese" by Brand et al., Developmental Science, 2002, Vol. 5, pp. 72-83) improves 2-year-olds' imitation. Children saw an adult perform a series of acts on four novel objects using either an infant-directed style (including larger range of motion and enhanced boundary marking) or an adult-directed style. Children's imitation of the acts was higher in the infant-directed condition relative to the adult-directed condition, and both types of demonstration increased imitation relative to baseline (no demonstration). We propose that motionese provides information about actions, objects, and intentionality, thereby enhancing toddlers' observational learning.

  6. Wavelet Analysis of the Periodicity and Correlation of the 420-ka Temperature, Carbon Dioxide, and Methane Time Series from the Vostok Ice Core

    NASA Astrophysics Data System (ADS)

    Zhang, J.; Huang, S.

    2010-12-01

    A good understanding of the history of Earth’s surface temperature and the excursion of atmospheric greenhouse gas composition is of crucial importance in reasoning the course and causes of climate change. However, identifying the variation and correspondence of different climate variables has been a challenging task due to the noisy, complex, and non-linear nature of paleoclimate records. Here we use wavelet technique to revisit the 420-ka temperature, carbon dioxide, and methane records from the ice core of Vostok station in East Antarctica [Petit et al., 1999, Nature, 399, 429] for the periodicity of and the correlation among these three variables. As with many other paleoclimate records, the sampling intervals of the Vostok records are different from variable to variable and from time to time. To allow for the application of continuous Morlet wavelet transform, cross-wavelet transform, and cross-wavelet coherence techniques, all three records were interpolated into 500-year equal interval time series with a cubic polynomial interpolation scheme. All three time series demonstrate the orbital eccentricity oscillation of about 100-ka as the most significant period with a lengthening trend towards the present day. Another periodicity common to all three records is the orbital tilt period of about 41 ka. However, the about 21 ka precession period can only be identified in the methane time series in the Morlet wavelet power spectrum. Our analysis further shows that temperature, CO2, and CH4 are well correlated, whereas the linkage of temperature with CO2 is stranger than that of temperature with CH4 and CO2 with CH4. In pairwise cross-wavelet transform and cross-wavelet coherence diagrams, almost all significant sections show in-phase correlations. Generally, the fluctuations of CO2 and CH4 appear to be either in sync with or slightly led by temperature variation, although there are isolated slots of millennium scales when the temperature - greenhouse gas

  7. Existence, uniqueness and regularity of a time-periodic probability density distribution arising in a sedimentation-diffusion problem

    NASA Technical Reports Server (NTRS)

    Nitsche, Ludwig C.; Nitsche, Johannes M.; Brenner, Howard

    1988-01-01

    The sedimentation and diffusion of a nonneutrally buoyant Brownian particle in vertical fluid-filled cylinder of finite length which is instantaneously inverted at regular intervals are investigated analytically. A one-dimensional convective-diffusive equation is derived to describe the temporal and spatial evolution of the probability density; a periodicity condition is formulated; the applicability of Fredholm theory is established; and the parameter-space regions are determined within which the existence and uniqueness of solutions are guaranteed. Numerical results for sample problems are presented graphically and briefly characterized.

  8. A 2-Year-Old Child's Memory of Hospitalization during Early Infancy

    ERIC Educational Resources Information Center

    Solter, Aletha

    2008-01-01

    A child who had had surgery at 5 months of age, and who had been treated at the time for post-traumatic symptoms (reported in a previous paper by the author), was interviewed 2 years later and almost 3 years later to test for possible verbal recall of his hospitalization. He appeared to have some memories of the experience at 29 months of age, and…

  9. Drainage estimation to aquifer and water use irrigation efficiency in semi-arid zone for a long period of time

    NASA Astrophysics Data System (ADS)

    Jiménez-Martínez, J.; Molinero-Huguet, J.; Candela, L.

    2009-04-01

    Water requirements for different crop types according to soil type and climate conditions play not only an important role in agricultural efficiency production, though also for water resources management and control of pollutants in drainage water. The key issue to attain these objectives is the irrigation efficiency. Application of computer codes for irrigation simulation constitutes a fast and inexpensive approach to study optimal agricultural management practices. To simulate daily water balance in the soil, vadose zone and aquifer the VisualBALAN V. 2.0 code was applied to an experimental area under irrigation characterized by its aridity. The test was carried out in three experimental plots for annual row crops (lettuce and melon), perennial vegetables (artichoke), and fruit trees (citrus) under common agricultural practices in open air for October 1999-September 2008. Drip irrigation was applied to crops production due to the scarcity of water resources and the need for water conservation. Water level change was monitored in the top unconfined aquifer for each experimental plot. Results of water balance modelling show a good agreement between observed and estimated water level values. For the study period, mean drainage obtained values were 343 mm, 261 mm and 205 mm for lettuce and melon, artichoke and citrus respectively. Assessment of water use efficiency was based on the IE indicator proposed by the ASCE Task Committee. For the modelled period, water use efficiency was estimated as 73, 71 and 78 % of the applied dose (irrigation + precipitation) for lettuce and melon, artichoke and citrus, respectively.

  10. Time-resolved measurement of single pulse femtosecond laser-induced periodic surface structure formation induced by a pre-fabricated surface groove.

    PubMed

    Kafka, K R P; Austin, D R; Li, H; Yi, A Y; Cheng, J; Chowdhury, E A

    2015-07-27

    Time-resolved diffraction microscopy technique has been used to observe the formation of laser-induced periodic surface structures (LIPSS) from the interaction of a single femtosecond laser pulse (pump) with a nano-scale groove mechanically formed on a single-crystal Cu substrate. The interaction dynamics (0-1200 ps) was captured by diffracting a time-delayed, frequency-doubled pulse (probe) from nascent LIPSS formation induced by the pump with an infinity-conjugate microscopy setup. The LIPSS ripples are observed to form asynchronously, with the first one forming after 50 ps and others forming sequentially outward from the groove edge at larger time delays. A 1-D analytical model of electron heating including both the laser pulse and surface plasmon polariton excitation at the groove edge predicts ripple period, melt spot diameter, and qualitatively explains the asynchronous time-evolution of LIPSS formation.

  11. Efficacy of Salvage Radiotherapy Plus 2-Year Androgen Suppression for Postradical Prostatectomy Patients With PSA Relapse

    SciTech Connect

    Choo, Richard; Danjoux, Cyril; Gardner, Sandra; Morton, Gerard; Szumacher, Ewa; Loblaw, D. Andrew; Cheung, Patrick; Pearse, Maria

    2009-11-15

    Purpose: To determine the efficacy of a combined approach of radiotherapy (RT) plus 2-year androgen suppression (AS) as salvage treatment for prostate-specific antigen (PSA) relapse after radical prostatectomy (RP). Methods and Materials: Seventy-five patients with PSA relapse after RP were treated with salvage RT plus 2-year AS, as per a pilot, prospective study. AS started within 1 month after completion of salvage RT and consisted of nilutamide for 4 weeks and buserelin acetate depot subcutaneously every 2 months for 2 years. Relapse-free rate including freedom from PSA relapse was estimated using the Kaplan-Meier method. PSA relapse was defined as a PSA rise above 0.2 ng/mL with two consecutive increases over a minimum of 3 months. A Cox regression analysis was performed to evaluate prognostic factors for relapse. Results: Median age of the cohort was 63 years at the time of salvage RT. Median follow-up from salvage RT was 6.4 years. All achieved initially complete PSA response (< 0.2) with the protocol treatment. Relapse-free rate including the freedom from PSA relapse was 91.5% at 5 years and 78.6% at 7 years. Overall survival rate was 93.2% at both 5 and 7 years. On Cox regression analysis, pT3 stage and PSA relapse less than 2 years after RP were significant prognostic factors for relapse. Conclusion: The combined treatment of salvage RT plus 2-year AS yielded an encouraging result for patients with PSA relapse after RP and needs a confirmatory study.

  12. Cytokines as a predictor of clinical response following hip arthroscopy: minimum 2-year follow-up.

    PubMed

    Shapiro, Lauren M; Safran, Marc R; Maloney, William J; Goodman, Stuart B; Huddleston, James I; Bellino, Michael J; Scuderi, Gaetano J; Abrams, Geoffrey D

    2016-08-01

    Hip arthroscopy in patients with osteoarthritis has been shown to have suboptimal outcomes. Elevated cytokine concentrations in hip synovial fluid have previously been shown to be associated with cartilage pathology. The purpose of this study was to determine whether a relationship exists between hip synovial fluid cytokine concentration and clinical outcomes at a minimum of 2 years following hip arthroscopy. Seventeen patients without radiographic evidence of osteoarthritis had synovial fluid aspirated at time of portal establishment during hip arthroscopy. Analytes included fibronectin-aggrecan complex as well as a multiplex cytokine array. Patients completed the modified Harris Hip Score, Western Ontario and McMaster Universities Arthritis Index and the International Hip Outcomes Tool pre-operatively and at a minimum of 2 years following surgery. Pre and post-operative scores were compared with a paired t-test, and the association between cytokine values and clinical outcome scores was performed with Pearson's correlation coefficient with an alpha value of 0.05 set as significant. Sixteen of seventeen patients completed 2-year follow-up questionnaires (94%). There was a significant increase in pre-operative to post-operative score for each clinical outcome measure. No statistically significant correlation was seen between any of the intra-operative cytokine values and either the 2-year follow-up scores or the change from pre-operative to final follow-up outcome values. No statistically significant associations were seen between hip synovial fluid cytokine concentrations and 2-year follow-up clinical outcome assessment scores for those undergoing hip arthroscopy.

  13. Cytokines as a predictor of clinical response following hip arthroscopy: minimum 2-year follow-up

    PubMed Central

    Shapiro, Lauren M.; Safran, Marc R.; Maloney, William J.; Goodman, Stuart B.; Huddleston, James I.; Bellino, Michael J.; Scuderi, Gaetano J.; Abrams, Geoffrey D.

    2016-01-01

    Hip arthroscopy in patients with osteoarthritis has been shown to have suboptimal outcomes. Elevated cytokine concentrations in hip synovial fluid have previously been shown to be associated with cartilage pathology. The purpose of this study was to determine whether a relationship exists between hip synovial fluid cytokine concentration and clinical outcomes at a minimum of 2 years following hip arthroscopy. Seventeen patients without radiographic evidence of osteoarthritis had synovial fluid aspirated at time of portal establishment during hip arthroscopy. Analytes included fibronectin–aggrecan complex as well as a multiplex cytokine array. Patients completed the modified Harris Hip Score, Western Ontario and McMaster Universities Arthritis Index and the International Hip Outcomes Tool pre-operatively and at a minimum of 2 years following surgery. Pre and post-operative scores were compared with a paired t-test, and the association between cytokine values and clinical outcome scores was performed with Pearson’s correlation coefficient with an alpha value of 0.05 set as significant. Sixteen of seventeen patients completed 2-year follow-up questionnaires (94%). There was a significant increase in pre-operative to post-operative score for each clinical outcome measure. No statistically significant correlation was seen between any of the intra-operative cytokine values and either the 2-year follow-up scores or the change from pre-operative to final follow-up outcome values. No statistically significant associations were seen between hip synovial fluid cytokine concentrations and 2-year follow-up clinical outcome assessment scores for those undergoing hip arthroscopy. PMID:27583163

  14. Cytokines as a predictor of clinical response following hip arthroscopy: minimum 2-year follow-up.

    PubMed

    Shapiro, Lauren M; Safran, Marc R; Maloney, William J; Goodman, Stuart B; Huddleston, James I; Bellino, Michael J; Scuderi, Gaetano J; Abrams, Geoffrey D

    2016-08-01

    Hip arthroscopy in patients with osteoarthritis has been shown to have suboptimal outcomes. Elevated cytokine concentrations in hip synovial fluid have previously been shown to be associated with cartilage pathology. The purpose of this study was to determine whether a relationship exists between hip synovial fluid cytokine concentration and clinical outcomes at a minimum of 2 years following hip arthroscopy. Seventeen patients without radiographic evidence of osteoarthritis had synovial fluid aspirated at time of portal establishment during hip arthroscopy. Analytes included fibronectin-aggrecan complex as well as a multiplex cytokine array. Patients completed the modified Harris Hip Score, Western Ontario and McMaster Universities Arthritis Index and the International Hip Outcomes Tool pre-operatively and at a minimum of 2 years following surgery. Pre and post-operative scores were compared with a paired t-test, and the association between cytokine values and clinical outcome scores was performed with Pearson's correlation coefficient with an alpha value of 0.05 set as significant. Sixteen of seventeen patients completed 2-year follow-up questionnaires (94%). There was a significant increase in pre-operative to post-operative score for each clinical outcome measure. No statistically significant correlation was seen between any of the intra-operative cytokine values and either the 2-year follow-up scores or the change from pre-operative to final follow-up outcome values. No statistically significant associations were seen between hip synovial fluid cytokine concentrations and 2-year follow-up clinical outcome assessment scores for those undergoing hip arthroscopy. PMID:27583163

  15. Predictors of Dental Cleaning Over a Two-year Time Period Around Pregnancy Among Asian and Native Hawaiian or Other Pacific Islander Race Subgroups in Hawai‘i, 2009–2011

    PubMed Central

    Turnure, Matthew; Mattheus, Deborah J; Shannon, Maureen T

    2015-01-01

    Abstract Oral health disease is linked to several chronic diseases including adverse health outcomes around pregnancy. Optimizing a woman's oral health before, during, and after pregnancy can impact her health and the health of her children. Preventive, diagnostic, and restorative dental services can be done safely and effectively including during pregnancy. We examined data from the 2009–2011 Hawai‘i Pregnancy Risk Assessment Monitoring System (PRAMS) to assess the prevalence of dental cleanings over an approximately 2 year (Median: 2.0 years, Range:1.6–2.5 years) time period (12 months before pregnancy, during pregnancy, and in the first few months postpartum) among 4,735 mothers who recently had a live birth. Adjusted prevalence ratios (APR) of dental cleanings were calculated for both race and Medicaid/QUEST insurance status adjusting for maternal age and education. During a two-year span before, during, and after pregnancy an estimated 60.8% of women had dental cleanings. Native Hawaiian (APR=0.87; 95% CI=0.80–0.93), Other Pacific Islander (0.70; 0.58–0.83), Filipino (0.90; 0.82–0.97), and Chinese (0.76; 0.63–0.93) mothers were less likely to have had dental cleanings compared to white mothers. Additionally, mothers with Medicaid/QUEST health insurance (0.73; 0.68–0.79) were less likely to have had cleanings. More than one-third of recently pregnant mothers did not have dental cleanings in the approximately two-year time period. Native Hawaiian, Other Pacific Islander, Filipino, and Chinese mothers and those on Medicaid/QUEST health insurance were less likely to receive regular dental care. Identification of the reasons why these populations do not seek regular dental care can inform programmatic efforts to improve oral health outcomes for women and families. PMID:26535162

  16. 17 CFR 270.32a-3 - Exemption from provision of section 32(a)(1) regarding the time period during which a registered...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... section 32(a)(1) regarding the time period during which a registered management investment company must... management investment company must select an independent public accountant. (a) A registered management investment company (“company”) organized in a jurisdiction that does not require it to hold regular...

  17. 20 CFR 1002.116 - Is the time period for reporting back to an employer extended if the employee is hospitalized for...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Is the time period for reporting back to an employer extended if the employee is hospitalized for, or convalescing from, an illness or injury incurred in, or aggravated during, the performance of service? 1002.116 Section 1002.116 Employees' Benefits OFFICE OF THE ASSISTANT SECRETARY...

  18. 20 CFR 1002.116 - Is the time period for reporting back to an employer extended if the employee is hospitalized for...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Is the time period for reporting back to an employer extended if the employee is hospitalized for, or convalescing from, an illness or injury incurred in, or aggravated during, the performance of service? 1002.116 Section 1002.116 Employees' Benefits OFFICE OF THE ASSISTANT SECRETARY...

  19. Pial synangiosis in patients with moyamoya younger than 2 years of age.

    PubMed

    Jackson, Eric M; Lin, Ning; Manjila, Sunil; Scott, R Michael; Smith, Edward R

    2014-04-01

    Object Patients with moyamoya who are younger than 2 years of age represent a therapeutic challenge because of their frequent neurological instability and concomitant anesthetic risks. The authors report their experience with pial synangiosis revascularization in this population. Methods The authors reviewed the clinical and radiographic records of all patients with moyamoya in a consecutive series of patients under 2 years of age, who underwent cerebral revascularization surgery using pial synangiosis at a single institution. Results During a 12-year period (1994-2005), 34 procedures (bilateral in 15 patients, unilateral in 4) were performed in 19 patients younger than 2 years (out of a total of 456 procedures in 240 patients). Eighteen of these patients presented with either stroke or transient ischemic attack. The average age of the 19 patients at first surgery was 1.4 years (range 6 months-1.9 years). Unanticipated staged operations occurred in 3 patients, due to persistent electroencephalographic changes during the initial surgery in 2 cases and due to brain swelling during the procedure requiring ventriculostomy in the other. There were 2 perioperative strokes; both patients had postoperative seizures but made clinical recoveries. The average follow-up was 7 years (range 1-14 years). Long term, at follow-up, 13 patients (68%) were clinically independent for their age, with 8 (42%) having no significant deficit. Late complications included subdural hygroma evacuation (1), additional revascularization procedures performed years later for frontal lobe ischemia (2), late infarction (1), and asymptomatic ischemic change on routine follow-up MRI studies (1). All patients who had both pre- and postoperative angiography demonstrated progression of disease. Conclusions Despite the challenges inherent to this population, the majority of children with moyamoya under the age of 2 years have a good long-term prognosis. The data from this study support the use of pial

  20. Spectral self-imaging of time-periodic coherent frequency combs by parabolic cross-phase modulation.

    PubMed

    Maram, Reza; Azaña, José

    2013-11-18

    Integer and fractional spectral self-imaging effects are induced on infinite-duration periodic frequency combs (probe signal) using cross-phase modulation (XPM) with a parabolic pulse train as pump signal. Free-spectral-range tuning (fractional effects) or wavelength-shifting (integer effects) of the frequency comb can be achieved by changing the parabolic pulse peak power or/and repetition rate without affecting the spectral envelope shape and bandwidth of the original comb. For design purposes, we derive the complete family of different pump signals that allow implementing a desired spectral self-imaging process. Numerical simulation results validate our theoretical analysis. We also investigate the detrimental influence of group-delay walk-off and deviations in the nominal temporal shape or power of the pump pulses on the generated output frequency combs.