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Sample records for 200 200c 300

  1. 75 FR 10658 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... Model 737-100, -200, -200C, -300, -400, and -500 Series Airplanes AGENCY: Federal Aviation... existing airworthiness directive (AD) that applies to all Model 737-100, -200, -200C, -300, -400, and - 500...-100, -200, -200C, -300, -400, and -500 series airplanes. That NPRM was published in the...

  2. DYNAMIC LOADING OF TEFLON AT 200?C

    SciTech Connect

    Urtiew, P A; Forbes, J W; Tarver, C M; Vandersall, K S; Garcia, F

    2007-06-13

    Dynamic loading experiments were performed on inert Teflon (Polytetrafluoroethylene) samples, initially heated to the temperature of 200 C, to test its behavior under these conditions for its use in other heated experiments. Tests were performed in the 100 mm diameter bore propellant driven gas gun with piezo-resistive manganin pressure gauges imbedded into the samples to measure loading pressures. Experimental data provided new information on the shock velocity - particle velocity relationship for the heated material and showed no adverse effect of temperature on the insulating properties of the material.

  3. Operational characteristics of a 200 C LC parallel resonant circuit

    NASA Technical Reports Server (NTRS)

    Baumann, Eric D.; Hammoud, Ahmad N.

    1995-01-01

    Research efforts are currently underway at the NASA Lewis Research Center to design and demonstrate an inverter capable of operating with a baseplate temperature of 200 C. In support of this project, various electrical components including capacitors, inductors, transformers, cables, and semiconductor switches are being developed or evaluated for integration into the inverter. In this work, a parallel LC resonant circuit was constructed and evaluated under simultaneous electrical and thermal stressing. The tests were performed in the temperature range of 25 to 200 C with an applied voltage of up to 90 V, 20 kHz. The individual components were comprised of high temperature film capacitors and powder core inductors developed in-house. The circuit was characterized in terms of the component currents and case temperatures as well as frequency of resonance as a function of applied bias and temperature. The results obtained, which have indicated good functional stability up to 200 C, are presented and discussed.

  4. Regulation of miR-200c by Nuclear Receptors PPARα, LRH-1 and SHP

    PubMed Central

    Zhang, Yuxia; Yang, Zhihong; Whitby, Richard; Wang, Li

    2011-01-01

    We investigated regulation of miR-200c expression by nuclear receptors. Ectopic expression of miR-200c inhibited MHCC97H cell migration, which was abrogated by the synergistic effects of PPARα and LRH-1 siRNAs. The expression of miR-200c was decreased by PPARα/LRH-1 siRNAs and increased by SHP siRNAs, and overexpression of the receptors reversed the effects of their respective siRNAs. SHP siRNAs also drastically enhanced the ability of the LRH-1 agonist RJW100 to induce miR-200c and downregulate ZEB1 and ZEB2 proteins. Co-expression of PPARα and LRH-1 moderately transactivated the miR-200c promoter, which was repressed by SHP co-expression. RJW100 caused strong activation of the miR-200c promoter. This is the first report to demonstrate that miR-200c expression is controlled by nuclear receptors. PMID:22100809

  5. MiR-200c promotes bladder cancer cell migration and invasion by directly targeting RECK

    PubMed Central

    Cheng, Yidong; Zhang, Xiaolei; Li, Peng; Yang, Chengdi; Tang, Jinyuan; Deng, Xiaheng; Yang, Xiao; Tao, Jun; Lu, Qiang; Li, Pengchao

    2016-01-01

    Background Increasing evidence suggests that the dysregulation of certain microRNAs plays an important role in tumorigenesis and metastasis. MiR-200c exhibits a disordered expression in many tumors and presents dual roles in bladder cancer (BC). Therefore, the definite role of miR-200c in BC needs to be investigated further. Materials and methods Quantitative reverse transcription polymerase chain reaction was used to assess miR-200c expression. Cell invasion and migration were evaluated using wound healing and transwell assays. The luciferase reporter assay was used to identify the direct target of miR-200c. The expression of reversion-inducing cysteine-rich protein with kazal motifs (RECK) in BC tissues and adjacent nontumor tissues, as well as in BC cell lines, was detected through quantitative reverse transcription polymerase chain reaction, Western blot assay, and immunohistochemistry. Results The miR-200c expression was significantly upregulated in the BC tissues compared with the adjacent nontumor tissues. The downregulation of miR-200c significantly inhibited cell migration and invasion in the BC cell lines. The luciferase reporter assay showed that RECK was a direct target of miR-200c. The knockdown of RECK in the BC cell lines treated with anti-miR-200c elevated the previously attenuated cell migration and invasion. Conclusion Our findings indicated that miR-200c functions as oncogenes in BC and may provide a novel therapeutic strategy for the treatment of BC. PMID:27574450

  6. Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer

    PubMed Central

    2012-01-01

    Background MicroRNAs are aberrantly expressed and correlate with tumourigenesis and the progression of solid tumours. The miR-200 family determines the epithelial phenotype of cancer cells and regulates invasiveness and migration. Thus, we hypothesised that the quantitative detection of the miR-200 family as epithelial-specific microRNAs in the blood could be a useful clinical biomarker for gastric cancer (GC). Methods We initially validated the expression levels of miR-200a, 200b, 200c and 141 in GC cell lines (n = 2) and blood from healthy controls (n = 19) using real-time quantitative reverse transcription PCR (qRT-PCR). The microarray expression profiles of the miR-200 family in 160 paired samples of non-tumour gastric mucosae and GC were downloaded through ArrayExpress and analysed. MiR-200c was selected for clinical validation. The qRT-PCR prospective assessment of miR-200c was performed using 67 blood samples (52 stage I-IV GC patients and 15 controls); the area under the receiver operating characteristic curve (AUC-ROC) was estimated. The Kaplan-Meier and Breslow-Wilcoxon tests were used to assess the correlation of miR-200c with overall and progression-free survival (OS and PFS). Multivariate analyses were performed using the Cox model. Results The miR-200c blood expression levels in GC patients were significantly higher than in normal controls (p = 0.018). The AUC-ROC was 0.715 (p = 0.012). The sensitivity, specificity and accuracy rates of 65.4%, 100% and 73.1%, respectively, were observed. The levels of miR-200c in the blood above the cutoff defined by the ROC curve was found in 17.6% of stage I-II GC patients, 20.6% of stage III patients and 67.7% of stage IV patients (p < 0.001). The miR-200c expression levels were not associated with clinical or pathological characteristics or recent surgical procedures. There was a correlation (p = 0.016) with the number of lymph node metastases and the increased expression levels of miR-200c

  7. Development of a 1 kW, 200 C Mapham Inventor

    NASA Technical Reports Server (NTRS)

    Hammoud, Ahmad; Gerber, Scott; Bauman, Eric; Overton, Eric; Myers, Ira; Bercaw, Robert

    1995-01-01

    Electronic systems and components are often exposed to high temperature environment in space-based applications, nuclear power facilities, and geothermal energy extraction fields. A key requirement for these systems is, therefore, to withstand the high temperature exposure while maintaining efficient and reliable operation. Efforts were taken to design and develop a high temperature power inverter capable of 200 C operation. A 1 kW, 20 kHz Mapham inverter was designed and evaluated as a function of temperature at different load levels. The inverter system, excluding its input, control, and logic circuits, was characterized at temperatures from ambient to 200 C at 0%, 50%, and 100% resistive loading. With an applied input voltage of 75 VDC, the inverter produced an output of 250 VAC. The results obtained, which indicate good operational characteristics of the inverter up to 200 C, are presented and discussed.

  8. MicroRNA-200c modulates DUSP-1 expression in diabetes-induced cardiac hypertrophy.

    PubMed

    Singh, Gurinder Bir; Raut, Satish K; Khanna, Sanskriti; Kumar, Akhilesh; Sharma, Saurabh; Prasad, Rishikesh; Khullar, Madhu

    2017-01-01

    Mitogen-activated protein kinases (MAPKs) (ERK1/2, JNK, and p38) are upregulated in diabetic cardiomyopathy (DCM). Dual-specific phosphatase-1 (DUSP-1) has been reported to regulate the activity of MAPKs in cardiac hypertrophy; however, the role of DUSP-1 in regulating MAPKs activity in DCM is not known. MicroRNAs have been reported to regulate the expression of several genes in hypertrophied failing hearts. However, little is known about the microRNAs regulating DUSP-1 expression in diabetes-related cardiac hypertrophy. In the present study, we investigated the role of DUSP-1 and miR-200c in diabetes-induced cardiac hypertrophy. DCM was induced in Wistar rats by low-dose Streptozotocin high-fat diet for 12 weeks. Cardiac expression of ERK, p-38, JNK, DUSP-1, miR-200c, and hypertrophy markers (ANP and β-MHC) was studied in DCM in control rats and in high-glucose (HG)-treated rat neonatal cardiomyocytes. miR-200c inhibition was performed to validate DUSP-1 as target. A significant increase in phosphorylated ERK, p38, and JNK was observed in DCM model and in HG-treated cardiomyocytes (p < 0.05). Expression of DUSP-1 was significantly decreased in diabetes group and in HG-treated cardiomyocytes (p < 0.05). Increased expression of miR-200c was observed in DCM model and in HG-treated cardiomyocytes (p < 0.05). Inhibition of miR-200c induces the expression of the DUSP-1 causing decreased expression of phosphorylated ERK, p38, and JNK and attenuated cardiomyocyte hypertrophy in HG-treated cardiomyocytes. miR-200c plays a role in diabetes-associated cardiac hypertrophy by modulating expression of DUSP-1.

  9. Deutsch 100, 200, 300.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education, Winnipeg.

    Manitoba's curriculum guide for German 100, 200, and 300 is designed to (1) make teachers of these courses aware of the official policy concerning the nature, goals, and objectives of the courses and approved teaching materials, and (2) provide instructional guidelines. The guide provides information about three sets of teaching materials from…

  10. Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers

    PubMed Central

    Cochrane, Dawn R.; Howe, Erin N.; Spoelstra, Nicole S.; Richer, Jennifer K.

    2010-01-01

    We focus on unique roles of miR-200c in breast, ovarian, and endometrial cancers. Members of the miR-200 family target ZEB1, a transcription factor which represses E-cadherin and other genes involved in polarity. We demonstrate that the double negative feedback loop between miR-200c and ZEB1 is functional in some, but not all cell lines. Restoration of miR-200c to aggressive cancer cells causes a decrease in migration and invasion. These effects are independent of E-cadherin status. Additionally, we observe that restoration of miR-200c to ovarian cancer cells causes a decrease in adhesion to laminin. We have previously reported that reintroduction of miR-200c to aggressive cells that lack miR-200c expression restores sensitivity to paclitaxel. We now prove that this ability is a result of direct targeting of class III beta-tubulin (TUBB3). Introduction of a TUBB3 expression construct lacking the miR-200c target site into cells transfected with miR-200c mimic results in no change in sensitivity to paclitaxel. Lastly, we observe a decrease in proliferation in cells transfected with miR-200c mimic, and cells where ZEB1 is knocked down stably, demonstrating that the ability of miR-200c to enhance sensitivity to paclitaxel is not due to an increased proliferation rate. PMID:20049172

  11. Prognostic Value and Clinicopathology Significance of MicroRNA-200c Expression in Cancer: A Meta-Analysis

    PubMed Central

    Xu, Jing; Zhu, Weikang; Li, Yan; Yu, Yongchun

    2015-01-01

    MiR-200c has been shown to be related to cancer formation and progression. However, the prognostic and clinicopathologic significance of miR-200c expression in cancer remain inconclusive. We carried out this systematic review and meta-analysis to investigate the prognostic value of miR-200c expression in cancer. Pooled hazard ratios (HRs) of miR-200c for overall survival (OS) and progression-free survival (PFS) were calculated to measure the effective value of miR-200c expression on prognosis. The association between miR-200c expression and clinical significance was measured by odds ratios (ORs). Twenty-three studies were included in our meta-analysis. We found that miR-200c was not significantly correlated with OS (HR = 1.41, 95%Cl: 0.95-2.10; P = 0.09) and PFS (HR = 1.12, 95%Cl: 0.68-1.84; P = 0.67) in cancer. In our subgroup analysis, higher expression of miR-200c was significantly associated with poor OS in blood (HR = 2.10, 95%CI: 1.52-2.90, P<0.00001). Moreover, in clinicopathology analysis, miR-200c expression in blood was significantly associated with TNM stage, lymph node metastasis and distant metastasis. MiR-200c may have the potential to become a new blood biomarker to monitor cancer prognosis and progression. PMID:26035744

  12. Lithium based alloy-thionyl chloride cells for applications at temperatures to 200 C

    NASA Astrophysics Data System (ADS)

    Kane, P.; Marincic, N.; Epstein, J.; Lindsey, A.

    A long-life lithium battery for industrial applications at temperatures up to 200 C was developed by combining Li-based alloy anodes with oxyhalide electrolytes. Cathodes were fabricated by rolling the blend of polycarbonomonofluoride, a conductive carbon additive, and a binder, while anodes were fabricated as those used in oxyhalide cells, incorporating a modified anode current collector designed to prevent the formation of 'lithium islands' at the end of discharge; nonwoven glass fiber separators were pretreated to remove excessive binders and lubricants. Various active electrode surface areas were combined with a corresponding thickness of electrodes and separators, matched in capacity. Tests of the high-rate electrode structure, using Li-Mg alloy anode in conjunction with thionyl chloride electrolyte, have demonstrated that the battery with this anode can be used under abusive conditions such as short circuit and external heating (at 175 C). Raising the operating temperature to 200 C did require some modifications of regular cell hardware.

  13. BRCA mutations cause reduction in miR-200c expression in triple negative breast cancer.

    PubMed

    Erturk, Elif; Cecener, Gulsah; Tezcan, Gulcin; Egeli, Unal; Tunca, Berrin; Gokgoz, Sehsuvar; Tolunay, Sahsine; Tasdelen, Ismet

    2015-02-10

    Triple negative breast cancer (TNBC) is the most aggressive and poorly understood subclass of breast cancer (BC). Over the recent years, miRNA expression studies have been providing certain detailed overview that aberrant expression of miRNAs is associated with TNBC. Although TNBC tumors are strongly connected with loss of function of BRCA genes, there is no knowledge about the effect of BRCA mutation status on miRNA expressions in TNBC cases. The aims of this study were to evaluate the expression profile of miRNAs that plays role in TNBC progression and the role of BRCA mutations in their regulation. The expression level of BC associated 13 miRNAs was analyzed in 7 BRCA mutations positive, 6 BRCA mutations negative TNBC cases and 20 non-tumoral tissues using RT-PCR. According to RT2 Profiler PCR Array Data Analysis, let-7a expression was 4.67 fold reduced in TNBCs as compared to normal tissues (P=0.031). In addition, miR-200c expression was 5.75 fold reduced in BRCA mutation positive TNBC tumors (P=0.005). Analysis revealed a negative correlation between miR-200c and VEGFA expressions (r=-468). Thus, miR-200c may be involved in invasion and metastasis in TNBC cases with BRCA mutation. In this study we provide the knowledge on the first report of association between microRNA-200c and BRCA mutations in TNBC. Further studies and evaluations are required, but this miRNA may provide novel therapeutic molecular targets for TNBC treatment and new directions for the development of anticancer drugs.

  14. Prognostic Role of MicroRNA-200c-141 Cluster in Various Human Solid Malignant Neoplasms

    PubMed Central

    Li, Xiao-yang; Li, Hui; Bu, Jie; Xiong, Liang; Guo, Hong-bin; Liu, Li-hong; Xiao, Tao

    2015-01-01

    The miR-200 family has emerged recently as a noticeable marker for predicting cancer prognosis and tumor progression. We aimed to review the evidence of miR-200c-141 genomic cluster as prognostic biomarkers in cancers. The results suggested that high level of miR-200c had no significant impact on OS (HR = 1.14 [0.77–1.69], P = 0.501) and DFS/PFS (HR = 0.72 [0.45–1.14], P = 0.161). Stratified analyses revealed that high miR-200c expression was significantly related to poor OS in serum/plasma (HR = 2.12 [1.62–2.77], P = 0.000) but not in tissues (HR = 0.89 [0.58–1.37], P = 0.599). High miR-200c expression was significantly associated with favorable DFS/PFS in tissues (HR = 0.56 [0.43–0.73], P = 0.000) but worse DFS/PFS in serum/plasma (HR = 1.90 [1.08–3.36], P = 0.027). For miR-141, we found that high miR-141 expression predicted no significant impact on OS (HR = 1.18 [0.74–1.88], P = 0.482) but poor DFS/PFS (HR = 1.11 [1.04–1.20], P = 0.003). Similarly, subgroup analyses showed that high miR-141 expression predicted poor OS in serum/plasma (HR = 4.34 [2.30–8.21], P = 0.000) but not in tissues (HR = 1.00 [0.92–1.09], P = 0.093). High miR-141 expression was significantly associated with worse DFS/PFS in tissues (HR = 1.12 [1.04–1.20], P = 0.002) but not in serum/plasma (HR = 0.90 [0.44–1.83], P = 0.771). Our findings indicated that, compared to their tissue counterparts, the expression level of miR-200c and miR-141 in peripheral blood may be more effective for monitoring cancer prognosis. High miR-141 expression was better at predicting tumor progression than survival for malignant tumors. PMID:26556949

  15. Over expression of miR-200c suppresses invasion and restores methotrexate sensitivity in lung cancer A549 cells.

    PubMed

    Shan, Wulin; Zhang, Xiaolei; Li, Ming; Deng, Fang; Zhang, Jing

    2016-11-30

    MicroRNAs have become recognized as key players in the development of malignancy. MiR-200c can function as a tumor suppressor gene. However, the effect of miR-200c on methotrexate resistance remains unclear to date. This study aims to evaluate the function of miR-200c in lung cancer A549 cells. The data presented in our study demonstrated that the expression of miR-200c was down-regulated in methotrexate-resistant A549 cells. Over expression of miR-200c could significantly inhibit cell proliferation, induce G0/G1 cell cycle arrest and induce cell apoptosis. RT-PCR and Western blot assays showed that the expression of P53 and P21 were significantly increased with miR-200c overexpression. These results indicated that over expression of miR-200c might enhance the sensitivity of A549 cells to methotrexate through the P53/P21 pathway. Furthermore, miR-200c overexpression significantly inhibited cell migration and invasion with increasing the expression of E-cad and decreasing the expression of EZH2. In consequence, we provide a mechanism of acquired resistance to methotrexate that is caused by the loss of miR-200c in lung cancer cells. Along with this, our study demonstrates the complex network of microRNA mediated chemoresistance.

  16. Regulation of miR-200c by nuclear receptors PPAR{alpha}, LRH-1 and SHP

    SciTech Connect

    Zhang, Yuxia; Yang, Zhihong; Whitby, Richard; Wang, Li

    2011-12-09

    Highlights: Black-Right-Pointing-Pointer Knockdown of PPAR{alpha} and LRH-1 abolishes miR-200c inhibition of HCC cell migration. Black-Right-Pointing-Pointer SHP represses miR-200c expression via inhibition of the activity of PPAR{alpha} and LRH-1. Black-Right-Pointing-Pointer RJW100 exhibits strong ability to downregulate ZEB1 and ZEB2 proteins. -- Abstract: We investigated regulation of miR-200c expression by nuclear receptors. Ectopic expression of miR-200c inhibited MHCC97H cell migration, which was abrogated by the synergistic effects of PPAR{alpha} and LRH-1 siRNAs. The expression of miR-200c was decreased by PPAR{alpha}/LRH-1 siRNAs and increased by SHP siRNAs, and overexpression of the receptors reversed the effects of their respective siRNAs. SHP siRNAs also drastically enhanced the ability of the LRH-1 agonist RJW100 to induce miR-200c and downregulate ZEB1 and ZEB2 proteins. Co-expression of PPAR{alpha} and LRH-1 moderately transactivated the miR-200c promoter, which was repressed by SHP co-expression. RJW100 caused strong activation of the miR-200c promoter. This is the first report to demonstrate that miR-200c expression is controlled by nuclear receptors.

  17. MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells.

    PubMed

    Lo, Wen-Liang; Yu, Cheng-Chia; Chiou, Guang-Yuh; Chen, Yi-Wei; Huang, Pin-I; Chien, Chian-Shiu; Tseng, Ling-Ming; Chu, Pen-Yuan; Lu, Kai-Hsi; Chang, Kuo-Wei; Kao, Shou-Yen; Chiou, Shih-Hwa

    2011-03-01

    MicroRNA-200c (miR200c) is emerging as an important regulator of tumourigenicity and cancer metastasis with a strong capacity for inducing epithelial-mesenchymal transitions. However, the role of miR200c in head and neck squamous cell carcinoma (HNSCC) and HNSCC-associated cancer stem cells (HNSCC-CSCs) is unknown. In this study, the expression of miR200c in the regional metastatic lymph node of HNSCC tissues was significantly decreased, but BMI1 expression was increased as compared to parental tumours. Importantly, site-directed mutagenesis with a luciferase reporter assay showed that miR200c targeted the 3' UTR of BMI1 in HNSCC cells. Isolated HNSCC-derived ALDH1(+) /CD44(+) cells displayed CSC-like tumour initiating and radio-resistant properties. The expression levels of miR200c were significantly down-regulated while BMI1 was increased in HNSCC-ALDH1(+) /CD44(+) compared to the other subsets of HNSCC cells. Furthermore, increased miR200c expression or knockdown of BMI1 could significantly inhibit the malignant CSC-like properties of ALDH1(+) /CD44(+) cells. miR200c over-expression further down-regulated the expressions of ZEB1, Snail and N-cadherin, but up-regulated E-cadherin expression in ALDH1(+) /CD44(+) cells. Finally, a xenotransplantion study confirmed that over-expression of miR200c or BMI1 knockdown effectively inhibited the lung metastatic ability and prolonged the survival rate of ALDH1(+) /CD44(+) -transplanted mice. In summary, miR200c negatively modulates the expression of BMI1 but also significantly inhibits the metastatic capability of epithelial-mesenchymal transitions in malignant HNSCC by reducing the expression of BMI1/ZEB1. Restoration of miR200c in HNSCC and CSCs may be a promising therapeutic approach.

  18. A 200 C Universal Gate Driver Integrated Circuit for Extreme Environment Applications

    SciTech Connect

    Tolbert, Leon M; Huque, Mohammad A; Islam, Syed K; Blalock, Benjamin J

    2012-01-01

    High-temperature power converters (dc-dc, dc-ac, etc.) have enormous potential in extreme environment applications, including automotive, aerospace, geothermal, nuclear, and well logging. For successful realization of such high-temperature power conversion modules, the associated control electronics also need to perform at high temperature. This paper presents a silicon-on-insulator (SOI) based high-temperature gate driver integrated circuit (IC) incorporating an on-chip low-power temperature sensor and demonstrating an improved peak output current drive over our previously reported work. This driver IC has been primarily designed for automotive applications, where the underhood temperature can reach 200 C. This new gate driver prototype has been designed and implemented in a 0.8 {micro}m, 2-poly, and 3-metal bipolar CMOS-DMOS (Double-Diffused Metal-Oxide Semiconductor) on SOI process and has been successfully tested for up to 200 C ambient temperature driving a SiC MOSFET and a SiC normally-ON JFET. The salient feature of the proposed universal gate driver is its ability to drive power switches over a wide range of gate turn-ON voltages such as MOSFET (0 to 20 V), normally-OFF JFET (-7 to 3 V), and normally-ON JFET (-20 to 0 V). The measured peak output current capability of the driver is around 5 A and is thus capable of driving several power switches connected in parallel. An ultralow-power on-chip temperature supervisory circuit has also been integrated into the die to safeguard the driver circuit against excessive die temperature ({ge}220 C). This approach utilizes increased diode leakage current at higher temperature to monitor the die temperature. The power consumption of the proposed temperature sensor circuit is below 10 {micro}W for operating temperature up to 200 C.

  19. Switching Characteristics of a 4H-SiC Based Bipolar Junction Transistor to 200 C

    NASA Technical Reports Server (NTRS)

    Niedra, Janis M.

    2006-01-01

    Static curves and resistive load switching characteristics of a 600 V, 4 A rated, SiC-based NPN bipolar power transistor (BJT) were observed at selected temperatures from room to 200 C. All testing was done in a pulse mode at low duty cycle (approx.0.1 percent). Turn-on was driven by an adjustable base current pulse and turn-off was accelerated by a negative base voltage pulse of 7 V. These base drive signals were implemented by 850 V, gated power pulsers, having rise-times of roughly 10 ns, or less. Base charge sweep-out with a 7 V negative pulse did not produce the large reverse base current pulse seen in a comparably rated Si-based BJT. This may be due to a very low charge storage time. The decay of the collector current was more linear than its exponential-like rise. Switching observations were done at base drive currents (I(sub B)) up to 400 mA and collector currents (I(sub C)) up to 4 A, using a 100 Omega non-inductive load. At I(sub B) = 400 mA and I(sub C) = 4 A, turn-on times typically varied from 80 to 94 ns, over temperatures from 23 to 200 C. As expected, lowering the base drive greatly extended the turn-on time. Similarly, decreasing the load current to I(sub C) = 1 A with I(sub B) = 400 mA produced turn-on times as short as 34 ns. Over the 23 to 200 C range, with I(sub B) = 400 mA and I(sub C) = 4 A, turn-off times were in the range of 72 to 84 ns with the 7 V sweep-out.

  20. MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1.

    PubMed

    Sun, Quanquan; Liu, Tongxin; Yuan, Yawei; Guo, Zhenli; Xie, Guozhu; Du, Shasha; Lin, Xiaoshan; Xu, Zhixin; Liu, Minfeng; Wang, Wei; Yuan, Quan; Chen, Longhua

    2015-03-01

    Radioresistance is a major challenge during the treatment of breast cancer. A further understanding of the mechanisms of radioresistance could provide strategies to address this challenge. In our study, we compared the expression of miR-200c in four distinct breast cancer cell lines: two representative basal cancer cells (MDA-MB-231 and BT549) vs. two representative luminal cancer cells (MCF-7 and BT474). The results revealed practically lower expression of miR-200c in the two basal cancer cell lines and higher expression of miR-200c in luminal cancer cells compared to the normal breast epithelial cell line MCF-10A. Ectopic expression of miR-200c in MDA-MB-231 cells inhibited irradiation-induced autophagy and sensitized the breast cancer cells to irradiation. We also identified UBQLN1 as a direct functional target of miR-200c involved in irradiation-induced autophagy and radioresistance. In 35 human breast cancer tissue samples, we detected an inverse correlation between the expression of miR-200c vs. UBQLN1 and LC3. These results indicate that the identified miR-200c/UBQLN1-mediated autophagy pathway may help to elucidate radioresistance in human breast cancer and might represent a therapeutic strategy.

  1. Static and Switching Characteristics of a 4H-SiC Based BJT to 200 C

    NASA Technical Reports Server (NTRS)

    Niedra, Janis M.; Schwarze, Gene E.

    2006-01-01

    Static curves and resistive load switching characteristics of a 600 V, 4 A rated, SiC-based NPN bipolar power transistor (BJT) were observed at selected temperatures from 23 to 200 C. All testing was done in a pulse mode at low duty cycle (approx. 0.1 percent). Turn-on was driven by an adjustable base current pulse and turn-off was accelerated by a negative base voltage pulse of either 7 or 0.6 V. Switching observations were done at base drive currents (I(sub B)) up to 400 mA and collector currents (I(sub C)) up to 4 A, using a 100 OMEGA non-inductive load. At I(sub B) = 400 mA and I(sub C) = 4 A, turn-on times typically varied from 81 to 97 ns, over temperatures from 23 to 200 C. As expected, lowering the base drive greatly extended the turn-on time. Similarly, decreasing the load current to I(sub C) = 1 A with I(sub B) = 400 mA produced turn-on times as short as 30 ns. Over the 23 to 200 C range, with I(sub B) = 400 mA and I(sub C) = 4 A, turn-off times were in the range of 61 to 77 ns with the 7 V sweep-out and 130 to 150 ns with the 0.6 V sweep-out. At a fixed temperature and I(sub C), the turn-off time decreased slightly with decreasing I(sub B), for I(sub B) sufficient to still provide full turn-on. The ratio of conduction to switching losses is estimated, based on the observed I(sub C) transition times and static curves. An estimate at 200 kHz and a 50 percent duty cycle shows that under practicable conditions the two losses can be comparable. Hence the evidence obtained does not support the occasionally voiced concern of necessarily unacceptably high conduction losses in SiC-based BJTs.

  2. MicroRNA-200c delivered by solid lipid nanoparticles enhances the effect of paclitaxel on breast cancer stem cell

    PubMed Central

    Liu, Jingwen; Meng, Tingting; Yuan, Ming; Wen, Lijuan; Cheng, Bolin; Liu, Na; Huang, Xuan; Hong, Yun; Yuan, Hong; Hu, Fuqiang

    2016-01-01

    Background One of the major obstacles in the treatment of breast cancer is breast cancer stem cells (BCSC) which are resistant to standard chemotherapeutic drugs. It has been proven that microRNA-200c (miR-200c) can restore sensitivity to microtubule-targeting chemotherapeutic drugs by reducing the expression of class III β-tubulin. In this study, combination therapy with miR-200c and paclitaxel (PTX) mediated by lipid nanoparticles was investigated as an alternative strategy against BCSC. Materials and methods A cationic lipid 1,2-dioleoyl-3-trimethylammonium-propane was strategically selected to formulate solid lipid nanoparticles (SLN) for miR-200c delivery. Nanostructured lipid carriers (NLC) with 20 wt% oleic acid were prepared for PTX delivery. Mammospheres, which gained the characteristics of BCSC, were used as a cell model to evaluate the efficiency of combination therapy. Results The cationic SLN could condense anionic miRNA to form SLN/miRNA complexes via charge interactions and could protect miRNA from degradation by ribonuclease. SLN/miR-200c complexes achieved 11.6-fold expression of miR-200c after incubation for 24 hours, compared with that of Lipofectamine™ 2000/miR-200c complexes (*P<0.05). Intracellular drug release assay proved that miRNA can be released from SLN/miRNA complexes efficiently in 12 hours after cellular uptake. After BCSC were transfected with SLN/miR-200c, the expression of class III β-tubulin was effectively downregulated and the cellular cytotoxicity of PTX-loaded NLC (NLC/PTX) against BCSC was enhanced significantly (**P<0.01). Conclusion The results indicated that the cationic SLN could serve as a promising carrier for miRNA delivery. In addition, the combination therapy of miR-200c and PTX revealed a novel therapeutic strategy for the treatment of BCSC. PMID:28003747

  3. Nuclear Melt Glass Dissolution and Secondary Mineral Precipitation at 40 to 200C

    SciTech Connect

    Zavarin, M; Roberts, S; Viani, B; Pawloski, G; Rose, T

    2004-06-14

    Most long-lived radionuclides associated with an underground nuclear test are initially incorporated into melt glass and become part of the hydrologic source term (HST) only upon their release via glass dissolution (Pawloski et al., 2001). As the melt glass dissolves, secondary minerals precipitate. The types of secondary minerals that precipitate influence the water chemistry in and around the melt glass. The secondary minerals also provide a sorption sink to the released radionuclides. The changing water chemistry affects the rate of glass dissolution; it also affects the sorption behavior of the released radionuclides. This complex nature of glass dissolution and its important role in defining the HST requires a thorough understanding of glass dissolution and secondary mineral precipitation. The identity of secondary minerals formed at temperatures from 40 to 200 C are evaluated in this report to assist in that understanding.

  4. Controlled-strain rate tests at very low strain rates of 2618 aluminum at 200 C

    NASA Technical Reports Server (NTRS)

    Ding, J. L.; Lee, S. R.

    1988-01-01

    Constant strain rate tests and constant load creep tests were performed on 2618 aluminum at 200 C. The strain rates used in the constant strain rate tests were 10 to the minus 6, 10 to the minus 7, 10 to the minum 8, and 10 to the minus 9/sec. Due to the fact that the strain rates in both tests were comparable to each other, the similarities between them can therefore be studied. It was concluded that metals are essentially rate sensitive at elevated temperatures. The traditional definition of creep and plasticity used in the classical creep analysis is actually a reflection of the material behavior under different loading conditions. A constitutive equation based on the test data under one loading condition should work well for other loading conditions as long as the strain rates are in the same range as those under which the material constants are determined.

  5. Sevoflurane protects against hepatic ischemia/reperfusion injury by modulating microRNA-200c regulation in mice.

    PubMed

    Wu, Yamou; Gu, Chengyong; Huang, Xiaochen

    2016-12-01

    This present study was aimed to investigate the molecular mechanisms involved in sevoflurane protection of hepatic ischemia-reperfusion (I/R) injury. Firstly, we investigated the protective effects of sevoflurane against hepatic I/R injury. Biochemical analysis results showed that sevoflurane preconditioning significantly protected against hepatic I/R injury by reducing liver enzymes and improving antioxidant defense markers. We also found that sevoflurane attenuates I/R-induced hepatic cell death, by TUNEL staining, DNA fragmentation ELISA and PARP activity determination. Next, In order to find the molecular mechanism of sevoflurane preconditioning in hepatic I/R injury, we poured our attention to microRNAs regulation. We focused on miR-200c, one of microRNAs which screened from the gene expression omnibus (GEO). Furthermore, a hydrogen peroxide (H2O2)-induced oxidative stress apoptosis model was also established to mimic hepatic I/R injury, the effects of MiR-200c was investigated. We observed that MiR-200c inhibition decreased the H2O2-induced apoptosis of hepatic AML-12 cells. And also, ZEB1 is found as a target gene of miR-200c and is involved in H2O2-induced apoptosis. On the other hand, the in vivo model was established to examine whether sevoflurane protect against hepatic IR injury by downregulating MiR-200c. Together with the biochemical tests and apoptosis detection, results showed that over-expression of miR-200c significantly inhibited the protect effect of sevoflurane in Hepatic IR injury. Summarizing, sevoflurane preconditioning seems to ameliorate hepatic I/R injury in mice, mediated by mechanisms that include microRNA 200c down regulation. However, further more studies need to be carried out to verify this point.

  6. Regulation of miR‐200c and miR‐141 by Methylation in Prostate Cancer

    PubMed Central

    Lynch, Seodhna M.; O'Neill, Karla M.; McKenna, Michael M.; Walsh, Colum P.

    2016-01-01

    BACKGROUND In prostate cancer (PCa), abnormal expression of several microRNAs (miRNAs) has been previously reported. Increasing evidence shows that aberrant epigenetic regulation of miRNAs is a contributing factor to their altered expression in cancer. In this study, we investigate whether expression of miR‐200c and miR‐141 in PCa is related to the DNA methylation status of their promoter. METHODS PCR analysis of miR‐200c and miR‐141, and CpG methylation analysis of their common promoter, was performed in PCa cell‐lines and in archived prostate biopsy specimens. The biological significance of miR‐200c and miR‐141 expression in prostate cancer cells was assessed by a series of in vitro bioassays and the effect on proposed targets DNMT3A and TET1/TET3 was investigated. The effect on promoter methylation status in cells treated with demethylating agents was also examined. RESULTS miR‐200c and miR‐141 are both highly elevated in LNCaP, 22RV1, and DU145 cells, but significantly reduced in PC3 cells. This correlates inversely with the methylation status of the miR‐200c/miR‐141 promoter, which is unmethylated in LNCaP, 22RV1, and DU145 cells, but hypermethylated in PC3. In PC3 cells, miR‐200c and miR‐141 expression is subsequently elevated by treatment with the demethylating drug decitabine (5‐aza‐2′deoxycytidine) and by knockdown of DNA methyltransferase 1 (DNMT1), suggesting their expression is regulated by methylation. Expression of miR‐200c and miR‐141 in prostate biopsy tissue was inversely correlated with methylation in promoter CpG sites closest to the miR‐200c/miR‐141 loci. In vitro, over‐expression of miR‐200c in PC3 cells inhibited growth and clonogenic potential, as well as inducing apoptosis. Expression of the genes DNMT3A and TET1/TET3 were down‐regulated by miR‐200c and miR‐141 respectively. Finally, treatment with the soy isoflavone genistein caused demethylation of the promoter CpG sites closest to the mi

  7. Retracted: Glabridin attenuates the migratory and invasive capacity of breast cancer cells by activating microRNA-200c

    PubMed Central

    Ye, Xianqing; Jiang, Fei; Li, Yuan; Mu, Juan; Si, Lu; Wang, Xingxing; Ning, Shilong; Li, Zhong

    2014-01-01

    Current treatments for breast cancer, a common malignancy in human females, are less than satisfactory because of high rates of metastasis. Glabridin (GLA), which acts through the FAK/ROS signaling pathway, has been used as an antioxidant and anti-metastatic agent. However, little is known regarding the effect of microRNA (miRNA) on GLA's anti-metastatic activity. The miRNA-200 family, which is frequently expressed at low levels in triple negative breast cancers, inhibits metastasis by blocking the epithelial–mesenchymal transition. Here, we found that GLA attenuated the migratory and invasive capacity of breast cancer cells by activating miR-200c. GLA induced the mesenchymal–epithelial transition in vitro and in vivo, as determined by increased expression of the epithelial marker, E-cadherin, and decreased expression of the mesenchymal marker, vimentin. Overexpression of miR-200c enhanced the expression of E-cadherin and decreased the expression of vimentin. Furthermore, in MDA-MB-231 and BT-549 breast cancer cells exposed to GLA, knockdown of miR-200c blocked the GLA-induced mesenchymal–epithelial transition and alleviated the GLA-induced inhibition of migration and invasion. Thus, elevation of miR-200c by GLA has considerable therapeutic potential for anti-metastatic therapy for breast cancer patients. PMID:24754877

  8. Physics 200, 300 Interim Guide.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education, Winnipeg.

    This guide, developed for the physics 200, 300 program in Manitoba, is designed to articulate with previous science courses; provide concepts, processes, and skills which will enable students to continue in physics-related areas; and relate physics to practical applications in everyday life. It includes a program overview (with program goals and…

  9. Chemistry 200, 300 Interim Guide.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education, Winnipeg.

    This guide, developed for the chemistry 200, 300 program in Manitoba, is designed to articulate with previous science courses, provide concepts, processes, and skills which will enable students to continue in chemistry-related areas, and relate chemistry to practical applications in everyday life. It includes a program overview (with program goals…

  10. The role of MicroRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation

    PubMed Central

    Wendlandt, Erik B; Graff, Joel W; Gioannini, Theresa L; McCaffrey, Anton P; Wilson, Mary E

    2013-01-01

    Recognition of microbial products by members of the Toll-like receptor (TLR) family initiates intracellular signaling cascades that result in NF-κB activation and subsequent production of inflammatory cytokines. We explored the potential roles of microRNAs (miRNAs) in regulating TLR pathways. A target analysis approach to the TLR4 pathway adaptor molecules identified several putative targets of miR-200a, miR-200b and miR-200c. miRNA mimics were co-transfected with a NF-κB activity reporter plasmid into HEK293 cells stably expressing TLR4 (HEK293-TLR4). Mimics of both miR-200b and miR-200c, but not miR-200a, decreased NF-κB reporter activity in either untreated cells or in cells treated with endotoxin:MD2 as a TLR4 agonist. Transfection of HEK293-TLR4 cells with miR-200b or miR-200c significantly decreased expression of MyD88, whereas TLR4, IRAK-1 and TRAF-6 mRNAs were unaffected. When miR-200b or miR-200c mimics were transfected into the differentiated monocytic THP-1 cell line, the abundance of MyD88 transcripts, as well as LPS-induced expression of the pro-inflammatory molecules IL-6, CXCL9 and TNF-α were diminished. These data define miRNAs miR-200b and miR-200c as factors that modify the efficiency of TLR4 signaling through the MyD88-dependent pathway and can thus affect host innate defenses against microbial pathogens. PMID:22522429

  11. Strength of Hycon 3 HP Be-Cu and other copper alloys from 20 C to 200 C

    NASA Astrophysics Data System (ADS)

    Weggel, Robert J.; Ratka, John O.; Spiegelberg, William D.; Sakai, Yoshikazu

    1994-07-01

    To be suitable for high-performance water-cooled magnets a conductor must have an excellent combination of electrical conductivity and tensile strength at moderately elevated temperatures. We have measured the 0.2% yield and ultimate tensile strengths, elongation and modulus of five copper alloys, in the form of heavily cold-worked strip 0.4 mm to 1.2 mm thick, at temperatures up to 200 C. The alloys are Hycon 3 HP Be-Cu (UNS alloy C17510), a 24% silver-copper being developed by NRIM (Tsukuba, Japan), Glidcop(sup (R)), Zr-Cu and electrolytic tough pitch copper. Be-Cu, Zr-Cu and Ag-Cu all retained strength very well. Be-Cu decreased in U.T.S. only 10% from room temperature to 200 C, Zr-Cu, 15%. For Ag-Cu the decrease was 10% from 20 C to 150 C, and another 10% during the next 50 C. Glidcop weakened 20% by 150 C. So did ETP copper, whose strength then plummeted another 50% by 200 C. Except for Ag-Cu, with its filamentary microstructure, all alloys were isotropic within about 5%. The anisotropy of Ag-Cu was about 12%, with the transverse direction being the stronger.

  12. Correlation between EGFR amplification and the expression of microRNA-200c in primary glioblastoma multiforme.

    PubMed

    Serna, Eva; Lopez-Gines, Concha; Monleon, Daniel; Muñoz-Hidalgo, Lisandra; Callaghan, Robert C; Gil-Benso, Rosario; Martinetto, Horacio; Gregori-Romero, Aurelia; Gonzalez-Darder, Jose; Cerda-Nicolas, Miguel

    2014-01-01

    Extensive infiltration of the surrounding healthy brain tissue is a critical feature in glioblastoma. Several miRNAs have been related to gliomagenesis, some of them related with the EGFR pathway. We have evaluated whole-genome miRNA expression profiling associated with different EGFR amplification patterns, studied by fluorescence in situ hybridization in tissue microarrays, of 30 cases of primary glioblastoma multiforme, whose clinicopathological and immunohistochemical features have also been analyzed. MicroRNA-200c showed a very significant difference between tumors having or not EGFR amplification. This microRNA plays an important role in epithelial-mesenchymal transition, but its implication in the behavior of glioblastoma is largely unknown. With respect to EGFR status our cases were categorized into three groups: high level EGFR amplification, low level EGFR amplification, and no EGFR amplification. Our results showed that microRNA-200c and E-cadherin expression are down-regulated, while ZEB1 is up-regulated, when tumors showed a high level of EGFR amplification. Conversely, ZEB1 mRNA expression levels were significantly lower in the group of tumors without EGFR amplification. Tumors with a low level of EGFR amplification showed ZEB1 expression levels comparable to those detected in the group with a high level of amplification. In this study we provide what is to our knowledge the first report of association between microRNA-200c and EGFR amplification in glioblastomas.

  13. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the

  14. miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition

    PubMed Central

    Sulaiman, Siti A.; Ab Mutalib, Nurul-Syakima; Jamal, Rahman

    2016-01-01

    Among the gynecological malignancies, ovarian cancer is the most fatal due to its high mortality rate. Most of the identified cases are epithelial ovarian cancer (EOC) with five distinct subtypes: high-grade serous carcinoma, low-grade serous carcinoma, mucinous carcinoma, endometrioid carcinoma, and clear-cell carcinoma. Lack of an early diagnostic approach, high incidence of tumor relapse and the heterogenous characteristics between each EOC subtypes contribute to the difficulties in developing precise intervention and therapy for the patients. MicroRNAs (miRNAs) are single-stranded RNAs that have been shown to function as tumor suppressors or oncomiRs. The miR-200 family, especially miR-200c, has been shown to be implicated in the metastasis and invasion of ovarian carcinoma due to its functional regulation of epithelial-to-mesenchymal transition (EMT). This mini review is aimed to summarize the recent findings of the miR-200c functional role as well as its validated targets in the metastasis cascade of ovarian cancer, with a focus on EMT regulation. The potential of this miRNA in early diagnosis and its dual expression status are also discussed. PMID:27601996

  15. Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and the corresponding mechanism.

    PubMed

    Shi, Runlin; Xiao, Haibing; Yang, Tao; Chang, Lei; Tian, Yuanfeng; Wu, Bolin; Xu, Hua

    2014-12-01

    microRNAs (miRNAs) have played a key role in human tumorigenesis, tumor progression, and metastasis. On the one hand, miRNAs are aberrantly expressed in many types of human cancer; on the other hand, miRNAs can function as tumor suppressors or oncogenes that target many cancer-related genes. This study aimed to investigate the effects of miRNA-200c (miR-200c) on the biological behavior and mechanism of proliferation, migration, and invasion in the prostate cancer cell line Du145. In this study, Du145 cells were transfected with miR-200c mimics or negative control miR-NC by using an X-tremeGENE siRNA transfection reagent. The relative expression of miR-200c was measured by RT-PCR. The proliferation, migration, and invasion abilities of Du145 cells were detected by CCK8 assays, migration assays and invasion assays, respectively. The expressions of ZEB1, E-cadherin, and vimentin were observed by western blot. Results showed that DU145 cells exhibited a high expression of miR-200c compared with immortalized normal prostate epithelial cell RWPE-1. Du145 cells were then transfected with miR-200c mimics and displayed lower abilities of proliferation, migration, and invasion than those transfected with the negative control. The protein levels of ZEB1 and vimentin were expressed at a low extent in Du145 cells, which were transfected with miR-200c mimics; by contrast, E-cadherin was highly expressed. Hence, miR-200c could significantly inhibit the proliferation of the prostate cancer cell line Du145; likewise, miR-200c could inhibit migration and invasion by epithelial-mesenchymal transition.

  16. S-200C

    EPA Pesticide Factsheets

    Technical product bulletin: aka SHEENCLEAN, BILGE CLEAR, OIL GONE, this non-intrusive bioremediation agent (nutrient additive) used in oil spill cleanups is an accelerator for remediation of hydrocarbon spills or leaks in soil or sheen on water.

  17. The electrolyte challenge for a direct methanol-air polymer electrolyte fuel cell operating at temperatures up to 200 C

    NASA Technical Reports Server (NTRS)

    Savinell, Robert; Yeager, Ernest; Tryk, Donald; Landau, Uziel; Wainright, Jesse; Gervasio, Dominic; Cahan, Boris; Litt, Morton; Rogers, Charles; Scherson, Daniel

    1993-01-01

    Novel polymer electrolytes are being evaluated for use in a direct methanol-air fuel cell operating at temperatures in excess of 100 C. The evaluation includes tests of thermal stability, ionic conductivity, and vapor transport characteristics. The preliminary results obtained to date indicate that a high temperature polymer electrolyte fuel cell is feasible. For example, Nafion 117 when equilibrated with phosphoric acid has a conductivity of at least 0.4 Omega(exp -1)cm(exp -1) at temperatures up to 200 C in the presence of 400 torr of water vapor and methanol vapor cross over equivalent to 1 mA/cm(exp 2) under a one atmosphere methanol pressure differential at 135 C. Novel polymers are also showing similar encouraging results. The flexibility to modify and optimize the properties by custom synthesis of these novel polymers presents an exciting opportunity to develop an efficient and compact methanol fuel cell.

  18. The Protective Role of microRNA-200c in Alzheimer's Disease Pathologies Is Induced by Beta Amyloid-Triggered Endoplasmic Reticulum Stress

    PubMed Central

    Wu, Qi; Ye, Xiaoyang; Xiong, Yi; Zhu, Haili; Miao, Jianting; Zhang, Wei; Wan, Jun

    2016-01-01

    MicroRNAs are small non-coding RNAs that repress the expression of their target proteins. The roles of microRNAs in the development of Alzheimer's disease (AD) are not clear. In this study we show that miR-200c represses the expression of PTEN protein. PTEN downregulation by miR-200c supports the survival and differentiation of cultured neurons. AD is a progressive neurodegenerative disease signified by beta amyloid (Aβ) peptide aggregation and deposition. In a mouse model of AD that is induced by APPswe and PS1ΔE9 double transgenes, we found Aβ deposition results in neuronal ER stress that induces miR200c. Pharmacological blockade of ER stress inhibited Aβ-induced miR-200c overexpression in AD brains. MiR-200c was detected in the serum of both AD mice and human AD patients. These findings suggest that miR-200c functions as part of the neuronal cell-intrinsic adaptive machinery, and supports neuronal survival and differentiation in response to Aβ induced ER-stress by downregulating PTEN. PMID:28008308

  19. Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin.

    PubMed

    Hurteau, Gregory J; Carlson, J Andrew; Spivack, Simon D; Brock, Graham J

    2007-09-01

    MicroRNAs are approximately 22-nucleotide sequences thought to interact with multiple mRNAs resulting in either translational repression or degradation. We previously reported that several microRNAs had variable expression in mammalian cell lines, and we examined one, miR-200c, in more detail. A combination of bioinformatics and quantitative reverse transcription-PCR was used to identify potential targets and revealed that the zinc finger transcription factor transcription factor 8 (TCF8; also termed ZEB1, deltaEF1, Nil-2-alpha) had inversely proportional expression levels to miR-200c. Knockout experiments using anti-microRNA oligonucleotides increased TCF8 levels but with nonspecific effects. Therefore, to investigate target predictions, we overexpressed miR-200c in select cells lines. Ordinarily, the expression level of miR-200c in non-small-cell lung cancer A549 cells is low in contrast to normal human bronchial epithelial cells. Stable overexpression of miR-200c in A549 cells results in a loss of TCF8, an increase in expression of its regulatory target, E-cadherin, and altered cell morphology. In MCF7 (estrogen receptor-positive breast cancer) cells, there is endogenous expression of miR-200c and E-cadherin but TCF8 is absent. Conversely, MDA-MB-231 (estrogen receptor-negative) cells lack detectable miR-200c and E-cadherin (the latter reportedly due to promoter region methylation) but express TCF8. The ectopic expression of miR-200c in this cell line also reduced levels of TCF8, restored E-cadherin expression, and altered cell morphology. Because the down-regulation of E-cadherin is a crucial event in epithelial-to-mesenchymal transition, loss of miR-200c expression could play a significant role in the initiation of an invasive phenotype, and, equally, miR-200c overexpression holds potential for its reversal.

  20. 17 CFR 300.200 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false General. 300.200 Section 300.200 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 RULES OF THE SECURITIES INVESTOR PROTECTION CORPORATION Accounts Introduced by Other...

  1. 17 CFR 300.200 - General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false General. 300.200 Section 300.200 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 RULES OF THE SECURITIES INVESTOR PROTECTION CORPORATION Accounts Introduced by Other...

  2. 17 CFR 300.200 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false General. 300.200 Section 300.200 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 RULES OF THE SECURITIES INVESTOR PROTECTION CORPORATION Accounts Introduced by Other...

  3. 17 CFR 300.200 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false General. 300.200 Section 300.200 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 RULES OF THE SECURITIES INVESTOR PROTECTION CORPORATION Accounts Introduced by Other...

  4. 17 CFR 300.200 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false General. 300.200 Section 300.200 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 RULES OF THE SECURITIES INVESTOR PROTECTION CORPORATION Accounts Introduced by Other...

  5. 40 CFR 300.200 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 29 2013-07-01 2013-07-01 false General. 300.200 Section 300.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND... Community Right-to-Know Act of 1986” but referred to herein as “Title III.” Regulations implementing...

  6. Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1

    PubMed Central

    Sun, Libo; Lu, Yonggang; Dou, Lin; Huang, Xiuqing; Sun, Mingxiao; Pang, Cheng; Qu, Jing; Liu, Guanghui; Li, Jian

    2016-01-01

    Previous studies indicated that miR-200s participated in IL-6-induced hepatic insulin resistance. However, the role of miR-200s in hepatic lipid accumulation has not been elucidated. Here we found that miR-200b and miR-200c were reduced in the steatotic livers of mice fed a high-fat diet (HFD) and patients with nonalcoholic fatty liver disease. This down-regulation was accompanied by an increase in the expression of lipogenic proteins such as sterol regulatory element-binding protein 1 (SREBP1) and fatty acid synthase (FAS). The suppression of miR-200b and miR-200c in Hep1-6 and NCTC1469 hepatocytes enhanced intracellular triglyceride levels, which were associated with increased SREBP-1 and FAS protein levels. In contrast, the over-expression of miR-200b and miR-200c suppressed lipid accumulation and reduced the expression of SREBP1 and FAS in Hep1-6 and NCTC1469 cells transfected with miR-200b or miR-200c mimics. Importantly, the up-regulation of miR-200b and miR-200c could reverse oleic acid/palmitic acid-induced lipid accumulation in hepatocytes. A luciferase reporter assay identified that miR-200b and miR-200c could directly bind the 3′UTR of jun. JUN activated the transcription of srebp1 to increase lipid accumulation. The data also demonstrated that increased miR-200b and miR-200c expression might be associated with sitagliptin-reduced hepatic lipid accumulation in mice fed a HFD. These findings suggest, for the first time, that reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1. PMID:27166182

  7. Targeting the miR-200c/LIN28B axis in acquired EGFR-TKI resistance non-small cell lung cancer cells harboring EMT features

    PubMed Central

    Sato, Hiroki; Shien, Kazuhiko; Tomida, Shuta; Okayasu, Kazuhiro; Suzawa, Ken; Hashida, Shinsuke; Torigoe, Hidejiro; Watanabe, Mototsugu; Yamamoto, Hiromasa; Soh, Junichi; Asano, Hiroaki; Tsukuda, Kazunori; Miyoshi, Shinichiro; Toyooka, Shinichi

    2017-01-01

    MicroRNA (miR)-200 family members (miR-200s) are frequently silenced in advanced cancer and have been implicated in the process of epithelial-to-mesenchymal transition (EMT). We previously reported that miR-200s were silenced through promoter methylation in acquired EGFR-tyrosine kinase inhibitor (TKI) resistant non-small cell lung cancer (NSCLC) cells harboring EMT features. In this study, we examined the functional role of miR-200s in NSCLC cells and investigated a novel approach to overcoming acquired EGFR-TKI resistance. In the analysis of NSCLC cell lines, each of the miR-200s expression-silenced cell lines showed promoter methylation. Significant correlations between miR-200c silencing and several oncogenic pathway alterations, including EMT-changes and LIN28B overexpression, were observed in the database analysis. In addition, EGFR-wild type cell lines had lower miR-200s expression levels than EGFR-mutant cell lines. The introduction of miR-200c using pre-miR-200c caused LIN28B suppression in cells with acquired EGFR-TKI resistance that harbored EMT features. Interestingly, both the introduction of miR-200c and the knockdown of LIN28B produced an antitumor effect in acquired EGFR-TKI resistance cells, whereas these manipulations were not effective in parental cells. The miR-200c/LIN28B axis plays an important role in cells with acquired resistance to EGFR-TKI that harbor EMT features and might be a useful therapeutic target for overcoming resistance. PMID:28084458

  8. 75 FR 70102 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Model 777-200, - 200LR, -300, and -300ER Series Airplanes AGENCY: Federal Aviation Administration (FAA... 777-200, -200LR, -300, and -300ER series airplanes. This AD requires removing and repairing the... airworthiness directive (AD) that would apply to certain Model 777-200, -200LR, -300, and -300ER...

  9. 75 FR 17889 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ... Model 777-200, - 200LR, -300, and -300ER Series Airplanes AGENCY: Federal Aviation Administration (FAA... directive (AD) for certain Model 777-200, -200LR, -300, and -300ER series airplanes. This proposed AD would...) This AD applies to The Boeing Company Model 777-200, -200LR, -300, and -300ER series...

  10. 76 FR 2846 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... Company Model 777-200, - 200LR, -300, and -300ER Series Airplanes AGENCY: Federal Aviation Administration... Attention Service Bulletin 777-29-0032, dated August 9, 2007 (for Model 777-200, -200LR, -300, and -300ER..., -200LR, -300, and -300ER airplanes that require rubber FOD shields). Boeing Special Attention...

  11. Hepatitis C Virus Induced miR200c Down Modulates FAP-1, a Negative Regulator of Src Signaling and Promotes Hepatic Fibrosis

    PubMed Central

    Ramachandran, Sabarinathan; Ilias Basha, Haseeb; Sarma, Nayan J.; Lin, Yiing; Crippin, Jeffrey S.; Chapman, William C.; Mohanakumar, Thalachallour

    2013-01-01

    Hepatitis C virus (HCV) induced liver disease is the leading indication for liver transplantation (LTx). Reinfection and accelerated development of fibrosis is a universal phenomenon following LTx. The molecular events that lead to fibrosis following HCV infection still remains poorly defined. In this study, we determined microRNA (miRNA) and mRNA expression profiles in livers from chronic HCV patients and normals using microarrays. Using Genego software and pathway finder we performed an interactive analysis to identify target genes that are modulated by miRNAs. 22 miRNAs were up regulated (>2 fold) and 35 miRNAs were down regulated (>2fold) compared to controls. Liver from HCV patients demonstrated increased expression of 306 genes (>3 fold) and reduced expression of 133 genes (>3 fold). Combinatorial analysis of the networks modulated by the miRNAs identified regulation of the phospholipase C pathway (miR200c, miR20b, and miR31through cellular proto-oncogene tyrosine-protein kinase Src (cSrc)), response to growth factors and hormones (miR141, miR107 and miR200c through peroxisome proliferator-activated receptor alpha and extracellular-signal-regulated kinases, and regulation of cellular proliferation (miR20b, miR10b, and miR141 through cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1 p21). Real time PCR (RT-PCR) validation of the miRNA in HCV infected livers demonstrated a 3.3 ±0.9 fold increase in miR200c. In vitro transfection of fibroblasts with miR200c resulted in a 2.2 fold reduction in expression of tyrosine-protein phosphatase non-receptor type 13 or FAS associated phosphatase 1 (FAP-1) and 2.3 fold increase in expression of cSrc. miR200c transfection resulted in significant increases in expression of collagen and fibroblast growth factor (2.8 and 3.4 fold, p<0.05). Therefore, we propose that HCV induced increased expression of miR200c can down modulate the expression of FAP1, a critical regulator of Src and MAP kinase pathway that play

  12. 76 FR 63163 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ..., -300, and -300ER Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final... Boeing Company Model 777-200, -200LR, -300, and -300ER series airplanes; certificated in any category;...

  13. 75 FR 9137 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-01

    ... measurements taken at three locations. This proposed AD also would require new repetitive inspections, measurements, and overhaul of the carriage spindles, and applicable corrective actions. In addition, this..., and cracks) of the carriage spindle, repetitive measurements to determine the diameter of...

  14. 76 FR 47522 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... at BS 727 and in the radius of the auxiliary chord on airplanes that were not affected by the... inspections for cracks in the BS 727 frame outboard chords and the radius of the auxiliary chord, for certain... the frame outboard chord at BS 727 and in the radius of the auxiliary chord. The cracking in...

  15. 76 FR 72858 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... cracking of the reinforcement angle and shear web, and doing a detailed inspection for cracking of the STA 348.2 frame outer chord, inner chord, and reinforcement angle, and corrective actions if necessary..., reinforcement angle, and shear web; and of the door stop intercostals at S-14L through S16L. ]...

  16. 75 FR 43803 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... corrosion of each carriage spindle of the left and right outboard mid-flaps, and corrective action if... AD results from reports of fractures that resulted from stress corrosion and pitting along the length of the spindle and spindle diameter, and additional reports of corrosion on the outboard...

  17. 75 FR 19564 - Airworthiness Directives; The Boeing Company Model 737-200, -200C, -300, -400, and- 500 Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... in the skin, antenna support structure, and surrounding frames and stringers; depending on the... structure, and surrounding frames and stringers; and Internal detailed inspection for any crack or corrosion in the skin, antenna support structure, and surrounding frames and stringers. The initial...

  18. 76 FR 33988 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... resistance measurements, and modifying relay module assemblies. This AD also requires revising the... applicable, with new relays having a GFI feature, performing certain bonding resistance measurements, and...: Wiring Changes, Relay Replacements, and Certain Bonding Resistance Measurements for Certain Airplanes...

  19. 76 FR 63229 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... require installing an automatic shutoff system for the center and auxiliary tank fuel boost pumps, as... tank fuel boost pumps, as applicable. This proposed AD would also require revisions to the Limitations... require revising the maintenance program by incorporating new airworthiness limitations for fuel...

  20. 76 FR 3856 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ..., replacing the fuel pump power control relays for the main, center and auxiliary tanks, as applicable, with... relay module assemblies. The proposed AD also would require revising the maintenance program to... to the fuel pumps caused by electrical arcing that could introduce an ignition source in the...

  1. 76 FR 12619 - Airworthiness Directives; The Boeing Company 737-200, -200C, -300, -400, and -500 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ... the skin panels, which could result in sudden fracture and failure of the skin panels of the fuselage... fix fatigue cracking of the skin panels, which could result in sudden fracture and failure of the skin... the skin panels, which could result in sudden fracture and failure of the skin panels of the...

  2. 76 FR 74667 - Airworthiness Directives; The Boeing Company Model 737-200, -200C, -300, -400, and -500 Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ..., which could result in sudden fracture and failure of the fuselage skin panels, and consequent rapid...-milled steps, which could result in sudden fracture and failure of the fuselage skin panels,...

  3. 76 FR 54399 - Airworthiness Directives; The Boeing Company Model 737-200, -200C, -300, -400, and -500 Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... sudden fracture and failure of the fuselage skin panels, and consequent rapid decompression of the..., which could result in sudden fracture and failure of the fuselage skin panels, and consequent rapid... panels at the chem-milled steps, which could result in sudden fracture and failure of the fuselage...

  4. 75 FR 48620 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... flightcrew due to hypoxia (lack of oxygen in body), and consequent loss of control of the airplane. DATES: We... warning horn could result in incapacitation of the flightcrew due to hypoxia (lack of oxygen in body), and... requires revising the airplane flight manual (AFM) to advise the flightcrew to don oxygen masks as a...

  5. 76 FR 6529 - Airworthiness Directives; The Boeing Company Model 737-100, -200, -200C, -300, -400, and -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... the flightcrew due to hypoxia (lack of oxygen in body), and consequent loss of control of the airplane... the flightcrew due to hypoxia (lack of oxygen in body) and consequent loss of control of the airplane... above 10,000 ft MSL. RECALL Oxygen Masks and Regulators ON, 100% Crew Communications ESTABLISH...

  6. Demethylation drug 5-Aza-2′-deoxycytidine-induced upregulation of miR-200c inhibits the migration, invasion and epithelial-mesenchymal transition of clear cell renal cell carcinoma in vitro

    PubMed Central

    JIANG, JUAN; YI, BO; DING, SIQING; SUN, JIAN; CAO, WEI; LIU, MENGZI

    2016-01-01

    The microRNA (miR)-200 family has been found to be involved in the process of mesenchymal-epithelial transition during renal development. Deregulation of miR-200c has been suggested to be involved in clear cell renal cell carcinoma (ccRCC). However, the precise role of miR-200c in the regulation of ccRCC metastasis has not been previously reported. In the present study, it was observed that miR-200c was frequently downregulated in ccRCC tissue compared with matched adjacent normal tissue. The expression of miR-200c was additionally reduced in ccRCC cell lines when compared with levels in normal renal cells. The DNA demethylation drug 5-Aza-2′-deoxycytidine (Aza) was used to treat several ccRCC cell lines, and it was observed that the expression of miR-200c was significantly increased following Aza treatment. Furthermore, treatment with Aza markedly inhibited ccRCC cell invasion and migration, while treatment with miR-200c inhibitor significantly enhanced invasion and migration of ccRCC cells. In addition, Aza treatment significantly promoted expression of E-cadherin and inhibited the expression of N-cadherin, while the inhibition of miR-200c downregulated E-cadherin and upregulated the expression of N-cadherin, suggesting that miR-200c has a suppressive role in epithelial-mesenchymal transition (EMT) of ccRCC cells. In conclusion, it was suggested that demethylation drug Aza-induced upregulation of miR-200c may inhibit migration, invasion and EMT in ccRCC cells. PMID:27123083

  7. Molecular Mechanism of MicroRNA-200c Regulating Transforming Growth Factor-β (TGF-β)/SMAD Family Member 3 (SMAD3) Pathway by Targeting Zinc Finger E-Box Binding Homeobox 1 (ZEB1) in Hypospadias in Rats

    PubMed Central

    Qian, Chong; Dang, Xiangyang; Wang, Xianglin; Xu, Wei; Pang, Guijian; Chen, Yifeng; Liu, Chengbei

    2016-01-01

    Background The aim of this study was to explore effects of microRNA-200c regulating TGF-β/Smad3 pathway by targeting Zeb1 on the occurrence and development of hypospadias and to evaluate the relationship between microRNA-200c and occurrence of hypospadias. Material/Methods Pregnant rats with a gestational age of 12 days were allocated into 2 groups; one received gavage of DEHP-contained soybean oil (1 ml/day, 8 days; Group A) and the other had gavage of normal soybean oil (1 ml/day, 8 days; Group B). Baby rats with hypospadias from Group A were assigned to the model group (n=20) and healthy baby rats from Group B were assigned to the control group (n=20). Real-time quantitative polymerase chain reaction (qRT-PCR), immunohistochemistry and Western blot analysis were performed to detect microRNA-200c, Zeb1, TGF-β, and Smad3 mRNA and protein expressions in the model group (n=20) and the control group (n=20). The relationship between microRNA-200c and Zeb1 was detected using a dual-luciferase reporter gene experiment. After the in vitro intervention experiment in fetal rat penises, Western blot was used to detect the expression of Zeb1, TGF-β, and Smad3. Results In the model group, microRNA-200c was expressed at a low level, and microRNA-200c expression in control group was 2.1 times higher than in the model group (P<0.05). When compared with the control group, mRNA expressions, protein expressions, and positive rates of Zeb1, TGF-β, and Smad3 were higher in the model group (all P<0.01). Luciferase gene report determined that Zeb1 is a target gene of microRNA-200c. The in vitro intervention experiment in fetal rat penises found that a high concentration of microRNA-200c inhibited hypospadias occurrence by suppressing the expression of Zeb1, TGF-β, and Smad3. Conclusions MicroRNA-200c was expressed in hypospadias penis tissues at low levels and was negatively correlated with Zeb1 expression. MicroRNA-200c up-regulated Zeb1 expression to regulate the TGF-β/Smad3

  8. microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs.

    PubMed

    Pan, Yi; Liang, Hongwei; Chen, Weixu; Zhang, Hongjie; Wang, Nan; Wang, Feng; Zhang, Suyang; Liu, Yanqing; Zhao, Chihao; Yan, Xin; Zhang, Junfeng; Zhang, Chen-Yu; Gu, Hongwei; Zen, Ke; Chen, Xi

    2015-01-01

    MicroRNA-200b and microRNA-200c (miR-200b/c) are 2 of the most frequently upregulated oncomiRs in colorectal cancer cells. The role of miR-200b/c during colorectal tumorigenesis, however, remains unclear. In the present study, we report that miR-200b/c can promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs (RECK). Firstly, bioinformatics analysis predicted RECK as a conserved target of miR-200b/c. By overexpressing or knocking down miR-200b/c in colorectal cancer cells, we experimentally validated that miR-200b/c are direct regulators of RECK. Secondly, an inverse correlation between the levels of miR-200b/c and RECK protein was found in human colorectal cancer tissues and cell lines. Thirdly, we demonstrated that repression of RECK by miR-200b/c consequently triggered SKP2 (S-phase kinase-associated protein 2) elevation and p27(Kip1) (also known as cyclin-dependent kinase inhibitor 1B) degradation in colorectal cancer cells, which eventually promotes cancer cell proliferation. Finally, promoting tumor cell growth by miR-200b/c-targeting RECK was also observed in the xenograft mouse model. Taken together, our results demonstrate that miR-200b/c play a critical role in promoting colorectal tumorigenesis through inhibiting RECK expression and subsequently triggering SKP2 elevation and p27(Kip1) degradation.

  9. 24 CFR 200.300 - Nondiscrimination and fair housing policy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Nondiscrimination and fair housing policy. 200.300 Section 200.300 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Nondiscrimination and Fair...

  10. 50 CFR 300.200 - Purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REGULATIONS Identification and Certification of Nations § 300.200 Purpose and scope. The purpose of this... vessels engaged in fishing activities or practices on the high seas that target or incidentally...

  11. 76 FR 10288 - Airworthiness Directives; The Boeing Company Model 767-200, -300, -300F, and -400ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... Model 767-200, -300, -300F, and -400ER Series Airplanes AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) that applies to The Boeing Company Model 767-200, -300, and -300F series airplanes..., October 5, 2005), for certain Model 767-200, -300, and -300F series airplanes. That AD...

  12. Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c

    PubMed Central

    Narita, Michiko; Shimura, Eri; Nagasawa, Atsumi; Aiuchi, Toshiki; Suda, Yukari; Hamada, Yusuke; Ikegami, Daigo; Iwasawa, Chizuru; Arakawa, Kazuhiko; Igarashi, Katsuhide; Kuzumaki, Naoko; Yoshioka, Yusuke; Ochiya, Takahiro; Takeshima, Hideyuki; Ushijima, Toshikazu; Narita, Minoru

    2017-01-01

    Background The EGFR tyrosine kinase inhibitor gefitinib is used in therapy for non-small-cell lung cancer (NSCLC). However, its application is limited by resistance-accelerated disease progression, which is accompanied by the epithelial-to-mesenchymal transition (EMT). In the present study, we performed multiple expression analyses of microRNAs (miRNAs) and quantified the expression of several related EMT players in gefitinib-resistant NSCLC cells. Methods and results To establish gefitinib-resistant NSCLC cells, gefitinib-sensitive HCC827 cells, which exhibit an in-frame deletion [E746-A750] in EGFR exon 19, were exposed to gefitinib for at least 1.5 months. Next, to profile “gefitinib-resistant HCC827 (HCC827GR)” cells, which have a secondary T790M mutation in EGFR exon 20, a miRNA array analysis was performed in HCC827 and HCC827GR cells. The greatest differences were seen in the levels of miR-155 and miR-200c, which essentially disappeared in HCC827GR cells. In addition to these reductions, the levels of smad2 and zeb1, which are both key players in EMT and targets for miR-155 and miR-200c, respectively, were dramatically increased in HCC827GR cells. In HCC827GR cells, the expression of epithelial-cadherin (E-cadherin) was greatly reduced with repressive histone modifications, whereas vimentin, which is expressed in mesenchymal cells, was dramatically increased with active histone modifications. In another gefitinib-resistant NSCLC cell line (H1975 cells), similar to the findings in HCC827GR cells, both miR-155 and miR-200c were absent, and the EMT was induced along with epigenetic modifications. Interestingly, the inhibition of both miR-155 and miR-200c in HCC827 cells without gefitinib induced significant increases in smad2 and zeb1 along with a dramatic decrease in E-cadherin and a slight increase in vimentin. Furthermore, although the inhibition of these miRNAs in HCC827 cells decreased gefitinib sensitivity, this dual-inhibition in HCC827 cells without

  13. 75 FR 3125 - Airworthiness Directives; Airbus Model A330-200, A330-300, A340-200, and A340-300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ...-16152; AD 2009-26-13] RIN 2120-AA64 Airworthiness Directives; Airbus Model A330-200, A330-300, A340- 200,and A340-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... 1, 2009. Manual. Airbus A340-200/-300 Structural 64 October 1, 2008. Repair Manual. Airbus...

  14. 75 FR 39814 - Airworthiness Directives; Airbus Model A330-200 and -300, and Model A340-200, -300, -500 and -600...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-13

    ...-200 and -300, and Model A340-200, -300, -500 and -600 Series Airplanes AGENCY: Federal Aviation...-300, A340-500, and A340-600 airplanes through the following Airbus modification (including but not... Model A340-300 airplanes through Mod 50108 (partial BCRC). Subject (d) Air Transport Association...

  15. 76 FR 15872 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ...-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of...-200 and -300 series airplanes and Model A340-200, -300, -500, and -600 series airplanes. That AD... FR 8610, February 15, 2011), for Airbus Model A340-200, -300, -500, and -600 series airplanes,...

  16. Fluid-Rock Interactions at the Interface between Reservoir Rock and Cap Rock: An Experimental Case Study Regarding Mineral Trapping at 54 and 200 C

    NASA Astrophysics Data System (ADS)

    Wigand, M. O.; Carey, J. W.; Kaszuba, J. P.; Hollis, W. K.

    2006-12-01

    Geologic sequestration (underground storage) of carbon dioxide (CO2) is the most feasible approach to mitigating CO2-induced global warming while maintaining the current fossil fuel-based economy. Although simple in principle, effective implementation of geologic sequestration will require significant development of the scientific understanding of interactions among injected CO2 (as a supercritical fluid), brine, and the reservoir rock. This paper presents the results of flow-through experiments that simulated a rising plume of supercritical carbon dioxide (SCCO2) interacting at the interface between reservoir rock and cap rock in a brine- saturated aquifer. We performed two high pressure flow-through experiments using powdered limestone and illite-rich shale separated by a frit with a pore size of 10 μm. One experiment was performed under in-situ pressure (2880 psi) and temperature (54°C) conditions of a typical oil reservoir in the Permian Basin. To increase the kinetic rates of the mineral reactions we also performed an experiment at elevated temperatures (200°C) but using the same boundary conditions for other experimental parameters such as pressure, rock samples, fluids, injection rates, and time span. Both experiments were performed over 3263 hours. After the experiment eight disks of equal size representing different reaction zones were cut to investigate the progressive fluid-rock interaction of the reservoir and cap rock with the mixture of SCCO2 and brine. Additionally, fluid samples were frequently collected and their compositions were analyzed using inductively coupled plasma mass spectrometry. At in-situ temperature conditions we determined an enrichment of B, Ba, Cr, Cu, Fe, K, Li, Mg, Na, Ni, Rb, Si, Sr, Ti, Zn, and sulfate in the collected brines, whereas Mn and chloride concentrations were depleted in comparison with the starting composition. Ca and Al showed uneven behavior with changes in enrichment and depletion during the experiment. At 200

  17. A Long-Lived FeIII-(Hydroperoxo) Intermediate in the Active H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Characterization by Mössbauer, Electron Paramagnetic Resonance, and Density Functional Theory Methods

    PubMed Central

    Meier, Katlyn K.; Rogers, Melanie S.; Kovaleva, Elena G.; Mbughuni, Michael M.; Bominaar, Emile L.; Lipscomb, John D.; Münck, Eckard

    2015-01-01

    The extradiol-cleaving dioxygenase homoprotocatechuate 2,3-dioxygenase (HPCD) binds substrate homoprotocatechuate (HPCA) and O2 sequentially in adjacent ligand sites of the active site FeII. Kinetic and spectroscopic studies of HPCD have elucidated catalytic roles of several active site residues, including the crucial acid base chemistry of His200. In the present study, reaction of the His200Cys (H200C) variant with native substrate HPCA resulted in a decrease in both kcat and the rate constants for the activation steps following O2 binding by > 400 fold. The reaction proceeds to form the correct extradiol product. This slow reaction allowed a long-lived (t1/2 = 1.5 min) intermediate, H200C-HPCAInt1 (Int1), to be trapped. Mössbauer and parallel mode electron paramagnetic resonance (EPR) studies show that Int1 contains an S1 = 5/2 FeIII center coupled to an SR = 1/2 radical to give a ground state with total spin S = 2 (J > 40 cm−1) in Hexch=JS^1⋅S^R. Density functional theory (DFT) property calculations for structural models Int1 is a (HPCA semiquinone•)FeIII(OOH) complex, in which OOH is protonated at the distal O and the substrate hydroxyls are deprotonated. By combining Mössbauer and EPR data of Int1 with DFT calculations, the orientations of the principal axes of the 57Fe electric field gradient and the zero-field splitting (ZFS) tensors (D = 1.6 cm−1, E/D = 0.05) were determined. This information was used to predict hyperfine splittings from bound 17OOH. DFT reactivity analysis suggests that Int1 can evolve from a ferromagnetically coupled FeIII-superoxo precursor by an inner-sphere proton-coupled-electron-transfer process. Our spectroscopic and DFT results suggest that a ferric hydroperoxo species is capable of extradiol catalysis. PMID:26485328

  18. 76 FR 1351 - Airworthiness Directives; The Boeing Company Model 757-200, -200CB, and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... Model 757-200, - 200CB, and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... exceed 30 flight cycles. Option B: At intervals not to exceed 300 flight cycles. Option C: At intervals... interval of 300 flight cycles to extend the Option B repeat inspection up to 330 flight cycles, and...

  19. 76 FR 6578 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ...-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Supplemental... apply to certain Model A330-200 and -300 series airplanes. That supplemental NPRM was published in...

  20. 76 FR 62661 - Airworthiness Directives; The Boeing Company Model 767-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-11

    ... Model 767-200 and - 300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... certain Model 767-200 and 767-300 series airplanes. This proposed AD would require installing cargo... (b) None. Applicability (c) This AD applies to The Boeing Company Model 767-200 and 767- 300...

  1. 76 FR 53305 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ...-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... applicability in the MCAI also identifies Airbus Model A340-200, -300, -500, and -600 series airplanes, this AD only applies to Airbus Model A330-200 and -300 series airplanes. FAA AD 2011-04-06, Amendment...

  2. 75 FR 4710 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes and A340-200, -300...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes and A340-200, -300, -500, and -600 Series Airplanes AGENCY:...

  3. 75 FR 54536 - Airworthiness Directives; Airbus Model A330-200 and -300 and A340-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Airbus Model A330-200 and -300 and A340-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA),...

  4. 75 FR 47207 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-200...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ...-200 and -300 Series Airplanes, and Model A340-200, -300, -500 and -600 Series Airplanes AGENCY... Register on July 13, 2010. That AD applies to certain Model A330-200 and -300 series airplanes, and Model A340-200, -300, -500 and -600 series airplanes. A certain service bulletin number in Note 3 of...

  5. 76 FR 29673 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-200 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-200 and -300 Series Airplanes... Service Bulletins A330-92-3077, Revision 01, dated March 29, 2010 (for Model A330-200 and -300 series airplanes); and A340-92-4078, Revision 01, dated April ] 9, 2010 (for Model A340-200 and -300...

  6. Contrôle de la température durant le processus de dégradation d'un acier Z12CNS20 en frottement avec un acier Z200C13

    NASA Astrophysics Data System (ADS)

    Khanafi-Benghalem, N.; Loucif, K.; Benghalem, K.; Boudoukha, H.; Louahdi, R.

    2005-05-01

    La température de contact lors des essais d'usure varie d'une manière spontanée et aléatoire. Cette température de contact dépend essentiellement de la nature du couple des matériaux en contact de la charge et de la vitesse. Cependant la mesure de la température est très difficile à effectuer compte tenu du choix de l'endroit de prise de la température et des phénomènes d'évacuation de la chaleur et de la dissipation de l'énergie. Dans ce travail nous exposons une méthode très simple de mesure de la température et nous étudions par conséquent la variation de la température du Z12CNS20 / Z200C13. Au cours des essais d'usure pour différentes vitesses de glissement, nous montrons en effet que la température augmente d'une manière progressive en fonction de la vitesse puis elle s'élève brutalement au fur et à mesure qu'on se rapproche du point de contact, et enfin nous prouvons par observation métallographique que l'échantillon subit un écoulement plastique provoqué par l'élévation de la température en fonction de la vitesse.

  7. 76 FR 56680 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes; Model A340-200 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... Model A330-200 and -300 Series Airplanes; Model A340-200 and -300 Series Airplanes; Model A340-500 and... Date Model A330 AOT A330-26A3052 April 19, 2011. Model A340-200, -300 AOT A340-200/300-26A4044...-26A3052, dated April 19, 2011 (for Model A330-200 and -300 series airplanes); Airbus AOT...

  8. 78 FR 68985 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Aircraft Electronic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... maintenance of the airplane. The existing regulations and guidance material did not anticipate these types of... Series Airplanes; Aircraft Electronic System Security Protection From Unauthorized Internal Access AGENCY... conditions are issued for the Boeing Model 777- 200, -300, and -300ER series airplanes. These airplanes,...

  9. 78 FR 76731 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Rechargeable Lithium...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ...These special conditions are issued for the Boeing Model 777- 200, -300, and -300ER series airplanes. These airplanes as modified by the ARINC Aerospace Company will have a novel or unusual design feature, specifically the installation of rechargeable lithium ion batteries and battery system that will be used on an International Communications Group (ICG) ePhone cordless cabin handset. The......

  10. 75 FR 42592 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ..., October 1, 2009). 767-200, -300, and - for fatigue cracking 300F series airplanes. and corrosion of the... midspar fitting tangs. We are issuing this AD to detect and correct fatigue cracking in the primary strut... specified in that AD are intended to prevent fatigue cracking in the primary strut structure and...

  11. 75 FR 46861 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ...-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Supplemental... revised the applicability statement of this supplemental NPRM to remove the Airbus Model A340-200,...

  12. 24 CFR 200.300 - Nondiscrimination and fair housing policy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Nondiscrimination and Fair Housing... part 5; and (b) The affirmative fair housing marketing requirements in 24 CFR part 200, subpart M...

  13. 200 TO 300 KVA Conditioned Power System - Development

    DTIC Science & Technology

    1985-03-01

    from the individual generator sources: 1. High Voltage dc ( HVDC ) (13.2 kv) 2. 115/200 Volts, 400 Hz ac 3. 28 Volt dc Also, each of these three types of...consideration. Option 1 has the advantage of not requiring a paralleling circuit. However, analysis shows that the High Voltage Direct Current ( HVDC ...High Voltage Direct Current ( HVDC ) system is to operate only between the 83% to 110% speed conditions, while the 400-Hz system operates from 53

  14. 76 FR 22005 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-200 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-20

    ...-16668; AD 2011-09-06] RIN 2120-AA64 Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration...

  15. 75 FR 38947 - Airworthiness Directives; Airbus Model A330-200 and A330-300 Series Airplanes, and Model A340-200...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ...-200 and A330-300 Series Airplanes, and Model A340-200, A340-300, A340-500, and A340-600 Series... A330-200 and A330-300 series Airbus Mandatory Service January 20, 2010. airplanes. Bulletin A330-34-3232, including Appendix 01. Model A340-200 and A340-300 series Airbus Mandatory Service January...

  16. 75 FR 28475 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and Model A340-300...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ...-200 and -300 Series Airplanes, and Model A340-300 Series Airplanes AGENCY: Federal Aviation... accomplishing the actions specified in the NPRM (for Model A340-300 series airplanes). We have revised... information for accomplishing the actions specified in the NPRM (for Model A330-200 and A330-300...

  17. 76 FR 24351 - Airworthiness Directives; Airbus Model A340-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... A340-200/-300 pre- modification 49203 (reinforcements of pylon primary structure for enhanced A340... economic impact, positive or negative, on a substantial number of small entities under the criteria of...

  18. 76 FR 18038 - Airworthiness Directives; Airbus Model A340-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ...-200 and -300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... condition on an aviation product. The MCAI describes the unsafe condition as: Two A340-300 aeroplanes... ``the MCAI''), to correct an unsafe condition for the specified products. The MCAI states: Two...

  19. 76 FR 61645 - Airworthiness Directives; Airbus Model A330-200 Series Airplanes; Model A330-300 Series Airplanes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ...-200 Series Airplanes; Model A330-300 Series Airplanes; Model A340-200 Series Airplanes; and Model A340-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of...

  20. 75 FR 25124 - Airworthiness Directives; The Boeing Company Model 737-200, -300, -400, and -500 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... Model 737-200, -300, -400, and -500 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... (AD) for certain Model 737-200, -300, -400, and -500 series airplanes. This proposed AD would require...) None. Applicability (c) This AD applies to The Boeing Company Model 737-200, -300, - 400, and...

  1. 76 FR 8612 - Airworthiness Directives; Airbus Model A340-200, -300, -500, and -600 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ...-200, -300, -500, and -600 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department... 2006-09-07, Amendment 39-14577 (71 FR 25919, May 3, 2006), for all Airbus Model A330-200 and -300, and A340-200 and -300 series airplanes, and A340-541 and -642 airplanes. That AD requires operators...

  2. 76 FR 4219 - Airworthiness Directives; Airbus Model A330-200 Series Airplanes; Model A330-300 Series Airplanes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ...-200 Series Airplanes; Model A330-300 Series Airplanes; Model A340-200 Series Airplanes; and Model A340-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT... airplanes) or TR150 (for Model A340-200 and -300 series airplanes), both Issue 1.0, both dated December...

  3. 75 FR 2057 - Airworthiness Directives; Airbus Model A340-200 and A340-300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-14

    ...-200 and A340-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department of... the A340-200/300 fleet has shown that the current utilization rate of the aeroplanes is different from...-200/300 fleet has shown that the current utilization rate of the aeroplanes is different from...

  4. 75 FR 38009 - Airworthiness Directives; The Boeing Company Model 737-200, -300, -400, -500, -600, -700, -800...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION... Model 737-200, -300, -400, -500, -600, -700, -800, and -900 Series Airplanes; Model 747-400 Series Airplanes; Model 757-200 and 757-300 Series Airplanes; Model 767-200, 767-300, and 767-400ER...

  5. Environmental assessment for the salvage/demolition of 200 West Area, 200 East Area, and 300 Area steam plants

    SciTech Connect

    1996-10-01

    This environmental assessment has been prepared to assess potential environmental impacts associated with the US Department of Energy`s proposed action: the salvage/demolition of the 200 West Area, 200 East Area, and 300 Area Steam Plants and steam distribution piping. Impact information will be used by the US Department of Energy, Richland Operations Office Manager, to determine if the proposed action is a major federal action significantly affecting the quality of the human environment. If the proposed action is determined to be major and significant, an environmental impact statement will be prepared. If the proposed action is determined not to be major and significant, a Finding of No Significant Impact (FONSI) will be issued and the action can proceed. The proposed action involves the salvage and demolition of the 200 West Area, 200 East Are, and 300 Area steam plants and their associated steam distribution piping, equipment, and ancillary facilities. Activities include the salvaging and recycling of all materials, wastes, and equipment where feasible, with waste minimization efforts utilized.

  6. 76 FR 23218 - Airworthiness Directives; Airbus Model A330-200, A330-300, A340-300, A340-500, and A340-600...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ...-200, A330-300, A340- 300, A340-500, and A340-600 Series Airplanes AGENCY: Federal Aviation... inoperative (from GO IF to NO GO) as an interim solution, limited to A330 and A340-300 fitted with electrical... retaining its requirements, requires the installation of: --a new BCM on A330 and A340-300 series...

  7. 76 FR 52217 - Airworthiness Directives; Airbus Model A330-200, A330-300, A340-300, A340-500, and A340-600...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-22

    ...-200, A330-300, A340- 300, A340-500, and A340-600 Series Airplanes AGENCY: Federal Aviation... dispatch with FCPC3 inoperative (from GO IF to NO GO) as an interim solution, limited to A330 and A340-300... and A340-200/-300 series aeroplanes fitted with electrical rudder, and --an improved PFTU on A330...

  8. The system water-sodium oxide-silicon dioxide at 200, 250, and 300°

    USGS Publications Warehouse

    Rowe, Jack J.; Fournier, Robert O.; Morey, G.W.

    1967-01-01

    Studies were made of the H2O-Na2O-SiO2 system at its vapor pressure at 200, 250, and 300??. Three different sodium trisilicate hydrates were encountered in the investigation. At 300??, Na2Si3O7??5H2O is found: at 250??, Na2Si3O7??6H2O; and at 200??, Na2Si3O7??11H2O. The liquid immiscibility previously reported to exist in the system was found to be a quenching phenomenon caused by the decomposition of the hydrates to unstable, supersaturated, viscous liquids. Under conditions where equilibrium is maintained, as temperature is lowered, the hydrates decompose to quartz, sodium disilicate, and liquid. The retrograde solubility of sodium disilicate and its tendency to form supersaturated solutions during heating from 25 to 250?? account for higher solubilities reported by others than were found in this study. The solubility of sodium disilicate in water is 26% at 200??, 9% at 250??, and 5% at 300??. Sodium metasilicate solubility is 38% at 200?? and 34% at 250??; this compound is incongruently soluble at 300??.

  9. Superconducting microstripline diplexer for CMB studies in the 200-300 GHz atmospheric window

    NASA Astrophysics Data System (ADS)

    Dabrowski, Elizabeth; Timbie, Peter T.

    2017-01-01

    The B-mode polarization signals of the Cosmic Microwave Background are obscured by astrophysical foregrounds. Future ground-based measurement programs such as CMB-S4 will remove foregrounds by placing at least two observing bands in each of the atmospheric windows, from about 30 GHz to about 300 GHz. We designed a superconducting microstripline filter to split the highest frequency window, from about 200 - 300 GHz, into two bands. We chose the centers of the bands to optimize removal of foreground radiation from Galactic dust. We present electromagnetic simulations of the design and measurements of a scale model of the filter.

  10. 76 FR 8610 - Airworthiness Directives; Airbus Model A340-200, -300, -500, and -600 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... A340-200, -300, -500, and -600 Series Airplanes AGENCY: Federal Aviation Administration (FAA...: Section 2-1 --A340-200/300 1-102 11 February 2009. Airworthiness Limitations. Section 2-2 --A340-500/600...

  11. Identification of miR-31-5p, miR-141-3p, miR-200c-3p, and GLT1 as human liver aging markers sensitive to donor-recipient age-mismatch in transplants.

    PubMed

    Capri, Miriam; Olivieri, Fabiola; Lanzarini, Catia; Remondini, Daniel; Borelli, Vincenzo; Lazzarini, Raffaella; Graciotti, Laura; Albertini, Maria Cristina; Bellavista, Elena; Santoro, Aurelia; Biondi, Fiammetta; Tagliafico, Enrico; Tenedini, Elena; Morsiani, Cristina; Pizza, Grazia; Vasuri, Francesco; D'Errico, Antonietta; Dazzi, Alessandro; Pellegrini, Sara; Magenta, Alessandra; D'Agostino, Marco; Capogrossi, Maurizio C; Cescon, Matteo; Rippo, Maria Rita; Procopio, Antonio Domenico; Franceschi, Claudio; Grazi, Gian Luca

    2017-04-01

    To understand why livers from aged donors are successfully used for transplants, we looked for markers of liver aging in 71 biopsies from donors aged 12-92 years before transplants and in 11 biopsies after transplants with high donor-recipient age-mismatch. We also assessed liver function in 36 age-mismatched recipients. The major findings were the following: (i) miR-31-5p, miR-141-3p, and miR-200c-3p increased with age, as assessed by microRNAs (miRs) and mRNA transcript profiling in 12 biopsies and results were validated by RT-qPCR in a total of 58 biopsies; (ii) telomere length measured by qPCR in 45 samples showed a significant age-dependent shortage; (iii) a bioinformatic approach combining transcriptome and miRs data identified putative miRs targets, the most informative being GLT1, a glutamate transporter expressed in hepatocytes. GLT1 was demonstrated by luciferase assay to be a target of miR-31-5p and miR-200c-3p, and both its mRNA (RT-qPCR) and protein (immunohistochemistry) significantly decreased with age in liver biopsies and in hepatic centrilobular zone, respectively; (iv) miR-31-5p, miR-141-3p and miR-200c-3p expression was significantly affected by recipient age (older environment) as assessed in eleven cases of donor-recipient extreme age-mismatch; (v) the analysis of recipients plasma by N-glycans profiling, capable of assessing liver functions and biological age, showed that liver function recovered after transplants, independently of age-mismatch, and recipients apparently 'rejuvenated' according to their glycomic age. In conclusion, we identified new markers of aging in human liver, their relevance in donor-recipient age-mismatches in transplantation, and offered positive evidence for the use of organs from old donors.

  12. 75 FR 9515 - Airworthiness Directives; Airbus Model A330-200 Series Airplanes and Model A340-200 and -300...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ...-16202; AD 2010-04-09] RIN 2120-AA64 Airworthiness Directives; Airbus Model A330-200 Series Airplanes and Model A340-200 and -300 Series Airplanes Correction In rule document 2010-3119 beginning on page 7940...

  13. 75 FR 78588 - Airworthiness Directives; The Boeing Company Model 777-200, -300, and -300ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ..., -300, and -300ER series airplanes. This AD requires installing Teflon sleeving under the clamps of... FR 3956, January 29, 2007) proposed to require installing Teflon sleeving under ] the clamps of... specified, unless the actions have already been done. Corrective Actions (Installing Teflon Sleeving,...

  14. 75 FR 81409 - Airworthiness Directives; The Boeing Company Model 737-200, -300, -400, and -500 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... repair must meet the certification basis of the airplane. Material Incorporated by Reference (n) You must... Model 737-200, -300, -400, and -500 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT..., -300, -400, and -500 series airplanes. This AD requires repetitive inspections for cracking of...

  15. 75 FR 10669 - Airworthiness Directives; The Boeing Company Model 747-100, 747-200B, 747-300, and 747SR Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... Model 747-100, 747- 200B, 747-300, and 747SR Series Airplanes AGENCY: Federal Aviation Administration... Model 747-100, 747-200B, 747-300, and 747SR series airplanes. This AD requires installation of a... airworthiness directive (AD) that would apply to certain Boeing Model 747-100, 747-200B, 747-300, and...

  16. 75 FR 3147 - Airworthiness Directives; The Boeing Company Model 747-100B SUD, -200B, -300, -400, and -400D...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... Model 747-100B SUD, -200B, -300, -400, and -400D Series Airplanes AGENCY: Federal Aviation... existing airworthiness directive (AD), which applies to certain Model 747-100B SUD, -200B, -300, -400, and..., -200B, -300, -400, and -400D series airplanes. That NPRM was published in the Federal Register on...

  17. 75 FR 39790 - Airworthiness Directives; Airbus Model A330-200 and -300 Airplanes and Model A340-200, -300, -500...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-13

    ... the FAA with promoting safe flight of civil aircraft in air commerce by prescribing regulations for...-24A5021 02 December 20, 2007. (2) Within 450 aircraft flight hours or 200 APU operating hours, whichever... before further flight. Repeat the inspections thereafter at intervals not to exceed 450 aircraft...

  18. 75 FR 55461 - Airworthiness Directives; Bombardier, Inc. Model DHC-8-200 and DHC-8-300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    .... Model DHC-8-200 and DHC-8-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), Department... the valve spring installed, the flapper valve is held closed by the valve spring, preventing gravity... spring, preventing gravity feed. In the event of scavenge system failure, the collector tank fuel...

  19. DISPLACEMENT CASCADE SIMULATION IN TUNGSTEN UP TO 200 KEV OF DAMAGE ENERGY AT 300, 1025, AND 2050 K

    SciTech Connect

    Setyawan, Wahyu; Nandipati, Giridhar; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

    2015-09-22

    We generated molecular dynamics database of primary defects that adequately covers the range of tungsten recoil energy imparted by 14-MeV neutrons. During this semi annual period, cascades at 150 and 200 keV at 300 and 1025 K were simulated. Overall, we included damage energy up to 200 keV at 300 and 1025 K, and up to 100 keV at 2050 K. We report the number of surviving Frenkel pairs (NF) and the size distribution of defect clusters. The slope of the NF curve versus cascade damage energy (EMD), on a log-log scale, changes at a transition energy (μ). For EMD > μ, the cascade forms interconnected damage regions that facilitate the formation of large clusters of defects. At 300 K and EMD = 200 keV, the largest size of interstitial cluster and vacancy cluster is 266 and 335, respectively. Similarly, at 1025 K and EMD = 200 keV, the largest size of interstitial cluster and vacancy cluster is 296 and 338, respectively. At 2050 K, large interstitial clusters also routinely form, but practically no large vacancy clusters do

  20. 76 FR 63156 - Airworthiness Directives; Fokker Services B.V. Model F.27 Mark 050, 200, 300, 400, 500, 600, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ...; AD 2011-21-01] RIN 2120-AA64 Airworthiness Directives; Fokker Services B.V. Model F.27 Mark 050, 200, 300, 400, 500, 600, and 700 Airplanes; and Model F.28 Airplanes AGENCY: Federal Aviation... AD applies to Fokker Services B.V. Model F.27 Mark 050, 200, 300, 400, 500, [[Page 63158

  1. Life Test Results for Water Heat Pipes Operating at 200 °C to 300 °C

    NASA Astrophysics Data System (ADS)

    Rosenfeld, John H.; Gernert, Nelson J.

    2008-01-01

    For lunar or planetary bases to be viable, a robust electric generating system will be required for powering the habitat. Water heat pipes offer an attractive solution for lunar base heat rejection, and would serve as a qualification for them on other long duration missions. Successful operation near the upper end of water operating range is a requirement for the application. Results are reported for life tests on water heat pipes that were operated at various temperatures between 200 °C and 300 °C. Tests were conducted on twenty three gravity-assisted water heat pipes. Eleven titanium/water heat pipes and ten Monel/water heat pipes were tested at temperatures above 200 °C. Two cupronickel heat pipes were also assembled and tested. Titanium alloys tested included CP-2 titanium, as well as two beta-titanium alloys, namely 15-3 and Nitinol alloys. Some of the titanium alloy life tests used wicks fabricated from CP-2 titanium screen or porous felt. Monel alloys tested included 400 and K-500 alloys. Some of the Monel heat pipes contained copper/nickel wicks that were fabricated by brazing nickel-plated copper felt metal wicks. Although most of the envelope/material combinations exhibit favorable results at 200 °C, some of the combinations failed at higher temperatures. Causes of failure included stress-creep of envelopes and corrosion at axial or end cap welds. This information represents a significant advance in selection of materials for 200 °C to 300 °C water heat pipes. Life testing work is being continued.

  2. Dedolomitization in NaCaCl brines from 100° to 200°C at 300 bars

    NASA Astrophysics Data System (ADS)

    Stoessell, R. K.; Klimentidis, R. E.; Prezbindowski, D. R.

    1987-04-01

    Dedolomitization experiments were run at 300 bars for 7 to 8 weeks at 100°, 150° and 200°C in chloride brines containing 2 m (molal) Na, 0.5 m Ca, and (except for 1 experiment) 0.02 m Sr. The "ordered" dolomite dissolved and low-Mg calcite back precipitated as a replacement and/or rim cement of equant spar calcite crystals 10 to 50 μm in diameter. Between 100° and 200°C the mode of calcite formation changed from direct precipitation into void space produced by dissolving dolomite to pseudomorphic replacement of dolomite. The dedolomitization textures formed in these experiments are similar to those found in the rock record. Solution compositions were monitored as a function of experimental time and imply that calcite-dolomite equilibrium was approached at 100°C and reached at 150° and 200°C. The final aqueous molality ratios of Ca:Mg were 14.2, 23.5, and 35.4, respectively, at 100°, 150°, and 200°C. The respective activity ratios, computed using Pitzer's model, were 14.3, 23.6, and 37.0, representing estimated equilibrium constants for the reaction: Mg2+ + 2 CaCO3 = CaMg( CO3) 2 + Ca2+. The estimated standard state enthalpy of reaction is 3.6 kcal between 150° and 200°C. The empirical Sr distribution coefficient, ( Sr/Ca) solid( Sr/Ca) liquid, for the precipitated calcite was determined from micro-probe analyses of the calcite and solution data. The average coefficient values increased with increasing temperature, being 0.027 (±0.008 = s. d. of 19 measurements), 0.048 (±0.017 = s. d. of 19 measurements), and 0.063 (±0.013 = s. d. of 32 measurements), respectively, at 100°, 150°, and 200°C.

  3. 75 FR 38007 - Airworthiness Directives; The Boeing Company Model 747-100, 747-100B, 747-100B SUD, 747-200B, 747...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ..., and 747SP Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule... SUD, 747-200B, 747-200C, 747-200F, 747-300, 747-400, 747-400F, 747SR, and 747SP series airplanes. This...). This AD results from reports of duct assemblies in the ECS with burned Boeing Material...

  4. 200 and 300 MeV/nucleon nuclear reactions responsible for single-event effects in microelectronics

    SciTech Connect

    Jaederstroem, H.; Murin, Yu.; Babain, Yu.; Chubarov, M.; Pljuschev, V.; Zubkov, M.; Nomokonov, P.; Olsson, N.; Blomgren, J.; Tippawan, U.; Westerberg, L.; Golubev, P.; Jakobsson, B.; Geren, L.; Tegner, P.-E.; Zartova, I.; Budzanowski, A.; Czech, B.; Skwirczynska, I.; Kondratiev, V.

    2008-04-15

    An experimental study of nuclear reactions between {sup 28}Si nuclei at 200 and 300 MeV/nucleon and hydrogen or deuterium target nuclei was performed at the CELSIUS storage ring in Uppsala, Sweden, to collect information about the reactions responsible for single-event effects in microelectronics. Inclusive data on {sup 28}Si fragmentation, as well as data on correlations between recoils and spectator protons or {alpha} particles are compared to predictions from the Dubna cascade model and the Japan Atomic Energy Research Institute version of the quantum molecular dynamics model. The comparison shows satisfactory agreement for inclusive data except for He fragments where low-energy sub-barrier fragments and recoiling fragments with very large momenta are produced much more frequently than predicted. The yield of exclusive data are also severely underestimated by the models whereas the charge distributions of recoils in these correlations compare well. The observed enhancement in He emission, which may well be important for the description of single-event effects, is most likely to be attributed to {alpha} clustering in {sup 28}Si nuclei.

  5. Deviate P200 and P300 in non-patient college students with high scores on the schizophrenia scale of the Minnesota Multiphasic Personality Inventory (MMPI).

    PubMed

    Ogura, C; Hirano, K; Nageishi, Y; Takeshita, S; Fukao, K; Hokama, H; Ohta, H; Arakaki, H

    1994-02-01

    Event-related potentials (ERPs) were examined in 16 college students who had high scores on the Schizophrenia Scale of the MMPI (HSS) but were without a hereditary disposition for major psychiatric disorders. 32 sex- and age-matched college students were used as controls. Subjects whose T scores were higher than 70 were designated the HSS subjects. ERPs were recorded during an auditory oddball task. Although neither the P300 latencies nor the P200 latencies differed between the two subject groups, the amplitudes of P300 to rare stimuli and P200 to frequent stimuli were lower in the HSS subjects than in the controls. These results suggest that deficits, both in the P300-related cognitive function to rare relevant stimuli, as well as matching and/or the comparison process for irrelevant frequent stimuli, may be present in HSS subjects. The HSS subjects, especially those with a combination of P300 and P200 deficits, even though without a hereditary diathesis for schizophrenia, may constitute one type of high-risk group.

  6. 75 FR 16651 - Airworthiness Directives; The Boeing Company Model 747-200C and -200F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... repetitive inspections to find fatigue cracking in the floor panel attachment fastener holes of the upper... initiating certain repetitive inspections. This new AD requires additional repetitive inspections to find... to find fatigue cracking in the permanent fastener holes of the upper chord of certain upper...

  7. 75 FR 5692 - Airworthiness Directives; The Boeing Company Model 747-200C and -200F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... structural integrity of the affected 7075 series aluminum alloy upper deck floor beam upper chords on... adequate to ensure the structural integrity of the affected 7075 series aluminum alloy upper deck...

  8. Effect of high-pressure treatment of ewe raw milk curd at 200 and 300 MPa on characteristics of Hispánico cheese.

    PubMed

    Alonso, R; Picon, A; Gaya, P; Fernández-García, E; Nuñez, M

    2012-07-01

    Hispánico cheese is a semihard variety made from a mixture of cow and ewe milks. Production of ewe milk declines in summer and autumn. To surmount the seasonal shortage of ewe milk and prevent the inactivation of milk enzymes by pasteurization, curd made in spring from ewe raw milk was pressurized at 200 and 300 MPa and stored frozen for 4 mo. Thawed ewe milk curds were added to fresh curd made from pasteurized cow milk for the manufacture of experimental Hispánico cheeses. Control cheese was made from a mixture of pasteurized cow and ewe milk in the same proportions as those used for experimental cheeses. Experimental cheeses exhibited lower dry matter content, higher aminopeptidase activity and total free amino acid concentration, and higher levels of acetic and propionic acids, aldehydes, alcohols, and esters compared with control cheese. In contrast, the concentration of total free fatty acids and ketones and the levels of textural parameters were significantly higher in control cheese. The use of ewe raw milk curd pressurized at 200 and 300 MPa, stored frozen and thawed for Hispánico cheese manufacture, was generally beneficial for cheese characteristics and increased cheese yield because of the lower dry matter content of experimental cheeses.

  9. [Long-latency components (N100, N200 and P300) of acoustic evoked potentials in prediction of mental recovery in severe traumatic brain injury].

    PubMed

    Oknina, L B; Sharova, E V; Zaĭtsev, O S; Zakharova, N E; Masherov, E L; Shekut'ev, G A; Kornienko, V N; Potapov, A A

    2011-01-01

    The authors analyzed correlations of amplitude and latency levels of N100, N200 and P300 components of acoustic evoked potentials (AEP) registered during sonic stimulation and counting of target-oriented stimuli in 22 patients in vegetative state and mutism as an outcome of traumatic brain injury. Results were analyzed with association of electrophysiological findings with data of diffusion-tensor MRI. 55 healthy volunteers were included into control group. It is described that patients in vegetative state with formal recovery to the level of clear consciousness develop all three components of AEP in response to target-oriented tone. The instruction "to counts" leads to their better development. Patients with restoration to minimal level of consciousness produce all components during audition of sounds and only N100 and N200 in response to standard tone after instruction "to count". It is discovered that levels of amplitude have bigger correlation according to Spearman's criterion with outcome in comparison to latency. There changes are more prominent in N100 and N200 components rather in P300. In addition, after instruction "to count sounds" the registered changes between stages of vegetative state and mutism are significant for leads of left hemisphere, and during audition of sounds--for sagittal leads. The study showed correspondence of acquired changes with MRI data. Chronic unconscious state is associated with changes in corpus callosum (degeneration fibers) and corticospinal tracts in the brainstem. The data are discussed in light of hypothesis of the role of morphofunctional disconnections (brainstem-thalamus and interhemispheric) in impairment of attention and in genesis of different forms of posttraumatic unconscious state.

  10. PULSION registered: A Versatile 200 to 300 mm Bridge Tool Plasma Immersion Ion Implanter for Ultra-Shallow Doping and Nanotechology Applications

    SciTech Connect

    Torregrosa, Frank; Etienne, Hasnaa; Sempere, Guillaume; Mathieu, Gilles; Roux, Laurent; Milesi, Frederic; Gonzatti, Frederic

    2008-11-03

    Thanks to the European Projects SEA-NET and PULLNANO, an industrial version of the IBS Plasma Ion Implantation tool has been installed in LETI for the fabrication of Ultra-Shallow Junctions for 45 and 32 nm CMOS on 200 and 300 mm wafers. In this paper, we present the main machine characteristics (layout, contamination, homogeneity, reproducibility, uptime) and we show that implanted wafers are compatible with the 32 nm nodes requirements. Then doping results (sheet resistance vs junction depth and leakage current) using several annealing technics are presented (laser, flash and spike anneals). In the second part of the paper, versatility of the tool is demonstrated with its use for other applications (3D doping, hydrogenation, solar cells...)

  11. MicroRNA-200c: A Novel Way to Attack Breast Cancer Metastases by Restoring the Epithelial Phenotype

    DTIC Science & Technology

    2012-02-01

    References [1] Lee RC, Feinbaum RL, Ambros V. The C . elegans heterochronic gene lin- 4 encodes small RNAs with antisense complementarity to lin-14. Cell...involved in developmental timing in C . elegans . Genes Dev 2001;15:2654–9.[24] Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme...human cells. Science 2005;309:1573–6. [ 42 ] Seggerson K, Tang L, Moss EG. Two genetic circuits repress the Caenorhab- ditis elegans heterochronic gene

  12. Exploring the cell: Sodium (beta-alumina) cupric chloride - Aluminum chloride - Sodium chloride between 136 and 200 C

    NASA Technical Reports Server (NTRS)

    Miller, R. O.

    1975-01-01

    Experiments were done with a molten-salt catholyte (initially CuCl2 in AlCl3-NaCl) separated from molten Na by beta alumina. The open-circuit reduction potentials were 4.3 and 3 volts for Cu++ and Cu+, respectively. High polarization and nonrechargeability characterized the cell's operation. The cell's ohmic resistance during discharge was higher than what would be expected from only the ionic resistance of the beta-alumina.

  13. MicroRNA-200c: A Novel Way to Attack Breast Cancer Metastases by Restoring the Epithelial Phenotype

    DTIC Science & Technology

    2012-12-01

    cancer stem cells with normal stem cells. Cell 138(3):592–603 59. Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, Hammond SM (2006...endometrial cancers are a heterogeneous group of poorly differentiated tumors (International Federation of Gynecology and Obstet- rics grade 3 endometrioid

  14. Productivity cycles of 200-300 years in the Antarctic Peninsula region: Understanding linkages among the sun, atmosphere, oceans, sea ice, and biota

    USGS Publications Warehouse

    Leventer, A.; Domack, E.W.; Ishman, S.E.; Brachfeld, S.; McClennen, C.E.; Manley, P.

    1996-01-01

    Compared to the rest of the world's oceans, high-resolution late Holocene paleoclimatic data from the Southern Ocean are still rare. We present a multiproxy record from a sediment core retrieved from a deep basin on the western side of the Antarctic Peninsula that reveals a dramatic perspective on paleoclimatic changes over the past 3700 yr. Analyses completed include measurement of magnetic susceptibility and granulometry, bed thickness, particle size, percent organic carbon, bulk density, and microscopic evaluation of diatom and benthic foraminiferal assemblages and abundances. Downcore variability of these parameters demonstrates the significance of both short-term cycles, which recur approximately every 200 yr, and longer term events (???2500 yr cycles) that are most likely related to global climatic fluctuations. In the upper 600 cm of the core, lower values of magnetic susceptibility (MS) are correlated with lower bulk density, the presence of thinly laminated units, specific diatom assemblages, and generally higher total organic carbon content. Below 600 cm, magnetic susceptibility is uniformly low, though variability in other parameters continues. The magnetic susceptibility signal is controlled primarily by dilution of ferromagnetic phases with biosiliceous material. This signal may be enhanced further by dissolution of magnetite in the magnetic susceptibility lows (high total organic carbon). The role of variable primary productivity and its relationship to paleoclimate is assessed through the diatom data. In particular, magnetic susceptibility lows are characterized by higher than normal abundances of Chaetoceros resting spores. Corethron criophilum and/or Rhizosolenia spp. also are found, as is a higher ratio of the most common species of Fragilariopsis versus species of Thalassiosira. These assemblages are indicative of periods of high primary productivity driven by the presence of a melt-water stabilized water column. The 200 yr cyclicity noted in

  15. 76 FR 38074 - Airworthiness Directives; The Boeing Company Model 747-100, 747-100B, 747-200B, 747-200C, 747...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... stretched- upper-deck configuration, as identified in Boeing Alert Service Bulletin 747-53A2303, dated June... is measured from the time of the stretched- upper-deck modification. (i) If no cracking is...

  16. 75 FR 1533 - Airworthiness Directives; The Boeing Company Model 747-200F, 747-200C, 747-400, 747-400D, and 747...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-12

    ... certain fuselage internal structure (i.e., Sections 42 and 46 fuselage frames, upper deck floor beams... (i.e., Section 41 fuselage frames where they connect to upper deck floor beams, and Section 41 fuselage frames between stringers (S-8 and S-12)), and related investigative/corrective actions...

  17. 75 FR 81427 - Airworthiness Directives; The Boeing Company Model 747-200C, -200F, -400, -400D, and -400F Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ...., Washington, DC 20590. FOR FURTHER INFORMATION CONTACT: Nicholas Han, Aerospace Engineer, Airframe Branch, ANM... Han, Aerospace Engineer, Airframe Branch, ANM-120S, FAA, Seattle ACO, 1601 Lind Avenue, SW.,...

  18. 75 FR 13046 - Airworthiness Directives; The Boeing Company Model 747-200C, -200F, -400, -400D, and -400F Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... procedures for repetitive external surface high frequency eddy current (HFEC), external low frequency eddy..., 2005: At the applicable time specified in Table 1 of this AD, do an external surface high frequency eddy current (HFEC), external low frequency eddy current (LFEC), and internal LFEC inspection,...

  19. 940nm QCW diode laser bars with 70% efficiency at 1 kW output power at 203K: analysis of remaining limits and path to higher efficiency and power at 200K and 300K

    NASA Astrophysics Data System (ADS)

    Frevert, C.; Bugge, F.; Knigge, S.; Ginolas, A.; Erbert, G.; Crump, P.

    2016-03-01

    Both high-energy-class laser facilities and commercial high-energy pulsed laser sources require reliable optical pumps with the highest pulse power and electro-optical efficiency. Although commercial quasi-continuous wave (QCW) diode laser bars reach output powers of 300…500 W further improvements are urgently sought to lower the cost per Watt, improve system performance and reduce overall system complexity. Diode laser bars operating at temperatures of around 200 K show significant advances in performance, and are particularly attractive in systems that use cryogenically cooled solid state lasers. We present the latest results on 940 nm, passively cooled, 4 mm long QCW diode bars which operate under pulse conditions of 1.2 ms, 10 Hz at an output power of 1 kW with efficiency of 70% at 203 K: a two-fold increase in power compared to 300 K, without compromising efficiency. We discuss how custom low-temperature design of the vertical layers can mitigate the limiting factors such as series resistance while sustaining high power levels. We then focus on the remaining obstacles to higher efficiency and power, and use a detailed study of multiple vertical structures to demonstrate that the properties of the active region are a major performance limit. Specifically, one key limit to series resistance is transport in the layers around the active region and the differential internal efficiency is closely correlated to the threshold current. Tailoring the barriers around the active region and reducing transparency current density thus promise bars with increased performance at temperatures of 200 K as well as 300 K.

  20. 46 CFR 117.200 - Survival craft-general.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Survival craft-general. 117.200 Section 117.200 Shipping... Number and Type of Survival Craft § 117.200 Survival craft—general. (a) Each survival craft required on a... craft they replace. (c) A summary of survival craft requirements is provided in Table 117.200(c)....

  1. 46 CFR 117.200 - Survival craft-general.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Survival craft-general. 117.200 Section 117.200 Shipping... Number and Type of Survival Craft § 117.200 Survival craft—general. (a) Each survival craft required on a... craft they replace. (c) A summary of survival craft requirements is provided in Table 117.200(c)....

  2. Static and Turn-on Switching Characteristics of 4H-Silicon Carbide SITs to 200 deg C

    NASA Technical Reports Server (NTRS)

    Niedra, Janis M.; Schwarze, Gene E.

    2005-01-01

    Test results are presented for normally-off 4H-SiC Static Induction Transistors (SITs) intended for power switching and are among the first normally-off such devices realized in SiC. At zero gate bias, the gate p-n junction depletion layers extend far enough into the conduction channel to cut off the channel. Application of forward gate bias narrows the depletion regions, opening up the channel to conduction by majority carriers. In the present devices, narrow vertical channels get pinched by depletion regions from opposite sides. Since the material is SiC, the devices are usable at temperatures above 150 C. Static curve and pulse mode switching observations were done at selected temperatures up to 200 C on a device with average static characteristics from a batch of similar devices. Gate and drain currents were limited to about 400 mA and 3.5 A, respectively. The drain voltage was limited to roughly 300 V, which is conservative for this 600 V rated device. At 23 C, 1 kW, or even more, could be pulse mode switched in 65 ns (10 to 90 percent) into a 100 load. But at 200 C, the switching capability is greatly reduced in large part by the excessive gate current required. Severe collapse of the saturated drain-to-source current was observed at 200 C. The relation of this property to channel mobility is reviewed.

  3. 20 CFR 664.205 - How is the “deficient in basic literacy skills” criterion in § 664.200(c)(1) defined and documented?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Computes or solves problems, reads, writes, or speaks English at or below the 8th grade level on a... to compute or solve problems, read, write, or speak English at a level necessary to function on...

  4. 20 CFR 664.205 - How is the “deficient in basic literacy skills” criterion in § 664.200(c)(1) defined and documented?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... problems, reads, writes, or speaks English at or below the 8th grade level on a generally accepted... problems, read, write, or speak English at a level necessary to function on the job, in the...

  5. 20 CFR 664.205 - How is the “deficient in basic literacy skills” criterion in § 664.200(c)(1) defined and documented?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Computes or solves problems, reads, writes, or speaks English at or below the 8th grade level on a... to compute or solve problems, read, write, or speak English at a level necessary to function on...

  6. 20 CFR 664.205 - How is the “deficient in basic literacy skills” criterion in § 664.200(c)(1) defined and documented?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... problems, reads, writes, or speaks English at or below the 8th grade level on a generally accepted... problems, read, write, or speak English at a level necessary to function on the job, in the...

  7. 20 CFR 664.205 - How is the “deficient in basic literacy skills” criterion in § 664.200(c)(1) defined and documented?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Computes or solves problems, reads, writes, or speaks English at or below the 8th grade level on a... to compute or solve problems, read, write, or speak English at a level necessary to function on...

  8. Plastic substrates for active matrix liquid crystal display incapable of withstanding processing temperature of over 200 C and method of fabrication

    DOEpatents

    Carey, P.G.; Smith, P.M.; Havens, J.H.; Jones, P.

    1999-01-05

    Bright-polarizer-free, active-matrix liquid crystal displays (AMLCDs) are formed on plastic substrates. The primary components of the display are a pixel circuit fabricated on one plastic substrate, an intervening liquid-crystal material, and a counter electrode on a second plastic substrate. The-pixel circuit contains one or more thin-film transistors (TFTs) and either a transparent or reflective pixel electrode manufactured at sufficiently low temperatures to avoid damage to the plastic substrate. Fabrication of the TFTs can be carried out at temperatures less than 100 C. The liquid crystal material is a commercially made nematic curvilinear aligned phase (NCAP) film. The counter electrode is comprised of a plastic substrate coated with a transparent conductor, such as indium-doped tin oxide (ITO). By coupling the active matrix with NCAP, a high-information content can be provided in a bright, fully plastic package. Applications include any low cost portable electronics containing flat displays where ruggedization of the display is desired. 12 figs.

  9. 34 CFR 300.300 - Parental consent.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and...

  10. 34 CFR 300.300 - Parental consent.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and...

  11. 34 CFR 300.300 - Parental consent.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and...

  12. 34 CFR 300.300 - Parental consent.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and...

  13. 34 CFR 300.300 - Parental consent.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and...

  14. 17 CFR 300.300 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section...

  15. 17 CFR 300.300 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section...

  16. 17 CFR 300.300 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section...

  17. 17 CFR 300.300 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section...

  18. 17 CFR 300.300 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section...

  19. Topographical map series in the Map Room of Institute and Museum of Military History in Budapest, Hungary between 1919-1945: Smaller scale series (1:100,000, 1:200,000, 1:300,000, 1:500,000, 1:750,000) of the territory of Central Europe

    NASA Astrophysics Data System (ADS)

    Jankó, A.; Bánfi, R.

    2009-04-01

    The Royal Hungarian State Mapping Institute kept the smaller scales series of the third military survey of the Austro-Hungarian Monarchy, too, so the scales 1:200,000 and 1:750,000 maps. The results of the supervisions of larger scales were transferred onto these scales, 1:200,000 and 1:750,000 maps, for the territory of Central Europe. In 1943 a scale 1:500,000 aerial map was accomplished, too, for the territory of Pannonian basin. There are many other important series in the Map Room between 1919 and 1945, including the WWII German edition 1:300,000 scale map series of Central Europe and Russia to the Ural Mts.; and a series of scale 1:100,000 for the territory of Poland and Russia between 1939-1940.

  20. 29 CFR 99.200 - Audit requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Audit requirements. 99.200 Section 99.200 Labor Office of the Secretary of Labor AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Audits § 99.200 Audit requirements. (a) Audit required. Non-Federal entities that expend $300,000 or more in...

  1. The effect of oxygen concentration on the boundary lubricating characteristics of an unformulated C-ether to 300 C

    NASA Technical Reports Server (NTRS)

    Jones, W. R., Jr.

    1973-01-01

    The effect of oxygen concentration on the boundary lubricating characteristics of an unformulated C-ether was studied with the use of a ball-on disk sliding-friction apparatus. Results were compared with those obtained with a polyphenyl ether. Experimental conditions included oxygen concentrations ranging from 20 percent (air) to 0.001 percent (nitrogen), a load of 1 kilogram, a sliding speed of 17 meters per minute, and disk temperatures ranging from 20 to 300 C (77 to 572 F). The C-ether yielded better boundary lubricating characteristics than did the polyphenyl ether in air and nitrogen over most of the temperature range. The C-ether exhibited lower wear at high oxygen levels (10 to 20 percent O2) from 25 to 200 C (77 to 392 F) and at low oxygen levels (0.001 to 1.0 percent O2) from 200 to 300 C (392 to 572 F). Friction polymer was observed around the wear scars of most test specimens. Friction polymer generation and its effect on wear are discussed in light of current theories.

  2. 200 Deg C Demonstration Transformer Operates Efficiently at 50 kHz

    NASA Technical Reports Server (NTRS)

    Niedra, Janis M.; Schwarze, Gene E. (Technical Monitor)

    2003-01-01

    A compact, high temperature demonstration transformer was constructed, using a moly permalloy powder core and Teflon -insulated copper wire. At 50 kHz and 200 C, this 1:2 ratio transformer is capable of 98 percent efficiency when operating at a specific power of 6.1 kW/kg at 4 kW. This roughly 7 cm diameter transformer has a mass of 0.65 kg. Although Teflon is unstable above 200 C, about the same electrical performance was seen at 250 C. A plot of winding loss versus frequency illustrates the need to control these losses at high frequency.

  3. 50 CFR 300.200 - Purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... sharks where the nation has not adopted a regulatory program for the conservation of sharks, comparable..., unreported, or unregulated fishing, reduce bycatch of protected living marine resources, and achieve...

  4. 76 FR 78138 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ... substantive verbal contact we receive about this AD. Costs of Compliance We estimate that this AD affects 129 airplanes of U.S. registry. This new AD adds no additional economic burden. The current costs for this AD are repeated for the convenience of affected operators, as follows: Estimated Costs Cost on...

  5. 75 FR 78596 - Airworthiness Directives; Hawker Beechcraft Corporation Models B200, B200GT, B300, and B300C...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ...-hours x $85 $100 $1,375 $123,750 pneumatic supply tube for the per hour = $1,275. tail de-ice system.... Action Labor Cost Parts cost product operators Fabricate placard (retained action 1 work-hour x $85 per... Bulletin SB 30- bulkhead at FS 347.750 with December 20, 2010 3889, Rev 1, dated Hytrel tubing part...

  6. 75 FR 80738 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ...; replacing certain MOV actuators with new MOV actuators; and measuring the electrical resistance of the bond... measuring the electrical resistance of the bond from the adapter plate to the airplane structure, and doing...) of this supplemental NPRM to clarify that measuring the electrical resistance of the bond from...

  7. 76 FR 24345 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ..., this AD requires doing certain bond resistance measurements, and corrective actions if necessary. This...) software. For certain other airplanes, that NPRM proposed to require doing certain bond resistance... resistance measurements and the installation of new panels, new fuel pump control GFI relays, software,...

  8. 75 FR 81508 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... other airplanes, this proposed AD would require doing certain bond resistance measurements, and... bulletin describes procedures for measuring the bond resistance between the terminal lugs on certain studs... after the effective date of this AD, do bonding resistance measurements to verify bonding...

  9. 76 FR 13074 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... horizontal stabilizer trim actuator (HSTA) after inspection and measurement; and if necessary, replacement of... horizontal stabilizer; repetitive installations of the horizontal stabilizer trim actuator (HSTA); and if... the horizontal stabilizer trim actuator (HSTA) components; the broken liner had worn and...

  10. 75 FR 74668 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, and -300ER Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... jackscrew fitting of the horizontal stabilizer; repetitive installations of the horizontal stabilizer trim... inspection of the horizontal stabilizer trim actuator (HSTA) components; the broken liner had worn and... broken into five pieces was found during a scheduled inspection of the horizontal stabilizer...

  11. 24 CFR 597.300 - HUD action and review of nominations for designation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND... and must be accompanied by a strategic plan, as required by § 597.200(c), and the certifications... evaluation. (d) Modification of the strategic plan, boundaries of nominated urban areas, and/or period...

  12. Effects of low temperature periodic annealing on the deep-level defects in 200 keV proton irradiated AlGaAs-GaAs solar cells

    NASA Technical Reports Server (NTRS)

    Li, S. S.; Chiu, T. T.; Loo, R. Y.

    1981-01-01

    The GaAs solar cell has shown good potential for space applications. However, degradation in performance occurred when the cells were irradiated by high energy electrons and protons in the space environment. The considered investigation is concerned with the effect of periodic thermal annealing on the deep-level defects induced by the 200 keV protons in the AlGaAs-GaAs solar cells. Protons at a fluence of 10 to the 11th P/sq cm were used in the irradiation cycle, while annealing temperatures of 200 C (for 24 hours), 300 C (six hours), and 400 C (six hours) were employed. The most likely candidate for the E(c) -0.71 eV electron trap observed in the 200 keV proton irradiated samples may be due to GaAs antisite, while the observed E(v) +0.18 eV hole trap has been attributed to the gallium vacancy related defect. The obtained results show that periodic annealing in the considered case does not offer any advantages over the one time annealing process.

  13. 34 CFR 300.158-300.159 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

  14. 34 CFR 300.125-300.128 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128 Children in...

  15. 34 CFR 300.538-300.599 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true 300.538-300.599 Section 300.538-300.599 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children Discipline Procedures §§ 300.538-300.599...

  16. 34 CFR 300.214-300.219 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219...

  17. 34 CFR 300.158-300.159 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

  18. 34 CFR 300.801-300.802 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802...

  19. 50 CFR 300.300 - Purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Purpose and scope. 300.300 Section 300.300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Vessels on IUU Vessel Lists § 300.300 Purpose and scope. (a) This subpart...

  20. 34 CFR 300.801-300.802 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802...

  1. 34 CFR 300.125-300.128 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128 Children in...

  2. 34 CFR 300.214-300.219 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219...

  3. 34 CFR 300.125-300.128 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128 Children in...

  4. 34 CFR 300.214-300.219 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219...

  5. 50 CFR 300.300 - Purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Purpose and scope. 300.300 Section 300.300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Vessels on IUU Vessel Lists § 300.300 Purpose and scope. (a) This subpart implements...

  6. 34 CFR 300.158-300.159 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

  7. 34 CFR 300.214-300.219 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219...

  8. 34 CFR 300.801-300.802 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802...

  9. 50 CFR 300.300 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Purpose and scope. 300.300 Section 300.300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Vessels on IUU Vessel Lists § 300.300 Purpose and scope. (a) This subpart implements...

  10. 34 CFR 300.214-300.219 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219...

  11. 34 CFR 300.125-300.128 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128 Children in...

  12. 50 CFR 300.300 - Purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Purpose and scope. 300.300 Section 300.300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Vessels on IUU Vessel Lists § 300.300 Purpose and scope. (a) This subpart...

  13. 34 CFR 300.801-300.802 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802...

  14. 50 CFR 300.300 - Purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Purpose and scope. 300.300 Section 300.300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Vessels on IUU Vessel Lists § 300.300 Purpose and scope. (a) This subpart...

  15. 34 CFR 300.125-300.128 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128 Children in...

  16. 34 CFR 300.538-300.599 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false 300.538-300.599 Section 300.538-300.599 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children Discipline Procedures §§ 300.538-300.599...

  17. 34 CFR 300.538-300.599 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false 300.538-300.599 Section 300.538-300.599 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children Discipline Procedures §§ 300.538-300.599...

  18. 34 CFR 300.538-300.599 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true 300.538-300.599 Section 300.538-300.599 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children Discipline Procedures §§ 300.538-300.599...

  19. 34 CFR 300.158-300.159 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

  20. 34 CFR 300.538-300.599 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false 300.538-300.599 Section 300.538-300.599 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children Discipline Procedures §§ 300.538-300.599...

  1. 34 CFR 300.158-300.159 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

  2. 34 CFR 300.801-300.802 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802...

  3. To designate the federal building currently known as Federal Office Building 8, located at 200 C Street Southwest in the District of Columbia, as the "Thomas P. O'Neill, Jr. Federal Building".

    THOMAS, 112th Congress

    Rep. Pelosi, Nancy [D-CA-8

    2012-11-27

    11/29/2012 Received in the Senate. (All Actions) Notes: For further action, see S.3687, which became Public Law 112-237 on 12/28/2012. Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  4. Synthesis of tourmaline solid solutions in the system Na2O-MgO-Al2O3-SiO2-B2O3-H2O-HCl and the distribution of Na between tourmaline and fluid at 300 to 700 °C and 200 MPa

    NASA Astrophysics Data System (ADS)

    v. Goerne, G.; Franz, G.; Heinrich, W.

    2001-05-01

    Tourmaline has been synthesized hydrothermally at 200 MPa between 300 and 700 °C from oxide mixtures with Mg-Al ratios for the end members dravite NaMg3Al6(Si6O18)(BO3)3(OH)3(OH) and Mg-foitite ❏(Mg2Al)Al6 (Si6O18)(BO3)3(OH)3(OH). Six different Na concentrations were investigated to determine the distribution of Na between tourmaline and fluid in the SiO2-saturated system Na2O-MgO-Al2O3-SiO2-B2O3-H2O-HCl. Synthetic tourmaline ranges from X-site vacant (❏) tourmaline (Mg-foitite) to nearly ideal dravite with Na=0.95 apfu. There are small, but significant, amounts of proton deficiency and negligible tetrahedral Al. Chemical variation is primarily caused by the substitutions Al❏Mg-1Na-1 and minor AlMg-1H-1. Varying amounts of Na and ❏ determine the Mg/Al ratios. Besides tourmaline and quartz, additional Mg-Al phases are chlorite and, at 700 °C, cordierite. Albite is also present at high Na concentrations in the bulk composition. The c dimension of the tourmaline crystals increases with Na in tourmaline. The amount of Na in the X-site depends strongly on the bulk concentration of Na in the system as well as on the temperature. These factors in turn control the phase assemblage and the composition of the fluid phase. For the assemblage tourmaline + quartz + chlorite/cordierite + fluid, a linear relationship exists between Na concentration in the fluid (quenched after the run) and tourmaline with temperature: T °C [±25 °C]=(Nafluid/Natur)×558.878-14.692 (r2=0.96). For the assemblage tourmaline + albite + quartz + fluid, it is: T °C [±15 °C]=(Nafluid/Natur)×845.813-6.231 (r2=0.95), where Nafluid is the concentration of Na+ in the final fluid (mol/l) and Natur is the number of Na cations in the X-site of tourmaline. The equations are valid in the temperature range of 500-715 °C. Our experiments demonstrate that the occupancy of the X-site in combination with the changing concentrations of Al and Mg can be used to monitor changes in the fluid composition

  5. 24 CFR 200.200 - What is the Appraiser Roster?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false What is the Appraiser Roster? 200.200 Section 200.200 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Appraiser Roster § 200.200 What is...

  6. CYBER 200 Applications Seminar

    NASA Technical Reports Server (NTRS)

    Gary, J. P. (Compiler)

    1984-01-01

    Applications suited for the CYBER 200 digital computer are discussed. Various areas of application including meteorology, algorithms, fluid dynamics, monte carlo methods, petroleum, electronic circuit simulation, biochemistry, lattice gauge theory, economics and ray tracing are discussed.

  7. Physics 300 Provincial Examination.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education and Training, Winnipeg.

    This document consists of the physics 300 provincial examination (English version), a separate "provincial summary report" on the results of giving the test, and a separate French language version of the examination. This physics examination contains a 53-item multiple choice section and an 12 item free response section. Subsections of…

  8. 34 CFR 300.521-300.529 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false 300.521-300.529 Section 300.521-300.529 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§...

  9. 34 CFR 300.521-300.529 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false 300.521-300.529 Section 300.521-300.529 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§...

  10. 34 CFR 300.521-300.529 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true 300.521-300.529 Section 300.521-300.529 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§...

  11. 34 CFR 300.521-300.529 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false 300.521-300.529 Section 300.521-300.529 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§...

  12. 34 CFR 300.521-300.529 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true 300.521-300.529 Section 300.521-300.529 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§...

  13. 300 Area Disturbance Report

    SciTech Connect

    LL Hale; MK Wright; NA Cadoret

    1999-01-07

    The objective of this study was to define areas of previous disturbance in the 300 Area of the U.S. Department of Energy (DOE) Hanford Site to eliminate these areas from the cultural resource review process, reduce cultural resource monitoring costs, and allow cultural resource specialists to focus on areas where subsurface disturbance is minimal or nonexistent. Research into available sources suggests that impacts from excavations have been significant wherever the following construction activities have occurred: building basements and pits, waste ponds, burial grounds, trenches, installation of subsurface pipelines, power poles, water hydrants, and well construction. Beyond the areas just mentioned, substrates in the' 300 Area consist of a complex, multidimen- sional mosaic composed of undisturbed stratigraphy, backfill, and disturbed sediments; Four Geographic Information System (GIS) maps were created to display known areas of disturbance in the 300 Area. These maps contain information gleaned from a variety of sources, but the primary sources include the Hanford GIS database system, engineer drawings, and historic maps. In addition to these maps, several assumptions can be made about areas of disturbance in the 300 Area as a result of this study: o o Buried pipelines are not always located where they are mapped. As a result, cultural resource monitors or specialists should not depend on maps depicting subsurface pipelines for accurate locations of previous disturbance. Temporary roads built in the early 1940s were placed on layers of sand and gravel 8 to 12 in. thick. Given this information, it is likely that substrates beneath these early roads are only minimally disturbed. Building foundations ranged from concrete slabs no more than 6 to 8 in. thick to deeply excavated pits and basements. Buildings constructed with slab foundations are more numerous than may be expected, and minimally disturbed substrates may be expected in these locations. Historic black

  14. Status of EXO-200

    SciTech Connect

    Ackerman, Nicole; /SLAC

    2011-12-06

    EXO-200 is the first phase of the Enriched Xenon Observatory (EXO) experiment, which searches for neutrinoless double beta decay in {sup 136}Xe to measure the mass and probe the Majorana nature of the neutrino. EXO-200 consists of 200 kg of liquid Xe enriched to 80% in {sup 136}Xe in an ultra-low background TPC. Energy resolution is enhanced through the simultaneous collection of scintillation light using Large Area Avalanche Photodiodes (LAAPD's) and ionization charge. It is being installed at the WIPP site in New Mexico, which provides a 2000 meter water-equivalent overburden. EXO-200 will begin taking data in 2009, with the expected two-year sensitivity to the half-life for neutrinoless double beta decay of 6.4 x 10{sup 25} years. According to the most recent nuclear matrix element calculations, this corresponds to an effective Majorana neutrino mass of 0.13 to 0.19 eV. It will also measure the two neutrino mode for the first time in {sup 136}Xe.

  15. Tracker 300 Software

    SciTech Connect

    Wysor, R. Wes

    2006-01-12

    The Tracker300 software is downloaded to an off-the-shelf product called RCM3400/RCM3410 made by Rabbit Semiconductor. The software is a closed loop control which computes the sun's position and provides stability compensation. Using the RCM3400/RCM3410 module, the software stores and retrieves parameters from the onboard flash. The software also allows for communication with a host. It will allow the parameters to be downloaded or uploaded, it will show the status of the controller, it will provide real-time feedback, and it will send command acknowledgements. The software will capture the GPS response and ensure the internal clock is set correctly.

  16. Neutral winds above 200Km at high latitudes

    NASA Technical Reports Server (NTRS)

    Meriwether, J. W.; Heppner, J. P.; Stolarik, J. D.; Wescott, E. M.

    1972-01-01

    Motion from multiple chemical releases between 200 and 300 km from 15 rockets launched from 4 high latitude locations are analyzed. The observations in the evening and midnight hours at magnetic altitudes or = 65 deg suggest that in these regions ion drag is the dominant force in driving neutral winds between 200 and 300 km. This conclusion is based on both the agreement between ion and neutral drift directions, and the fact that there are distinct changes in the wind associated with (a) the reversal in east-west ion drift at the Harang discontinuity, and (b) the transition from auroral belt, sunward ion drift and polar cap, anti-solar ion drift.

  17. 76 FR 6543 - Airworthiness Directives; Airbus Model A330-200 and -300 and A340-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... necessary, a general visual inspection to determine the status of the static discharges contour and sealing the static discharges contour if necessary, and installing front spar access hole covers). You may... inspection to determine the condition of the sealant covering the static discharges contour, and...

  18. 75 FR 15353 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and A340-200, -300...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... French standard airworthiness certificate or the date of issuance of the original French or EASA export... on which 10 or more years have accumulated since the date of issuance of the original French standard airworthiness certificate or the date of issuance of the original French or EASA export certificate...

  19. 75 FR 42589 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes, and A340-200, -300...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ... the date of issuance of the original French standard airworthiness certificate or the date of issuance of the original French or EASA export certificate of airworthiness as of the effective date of this... the date of issuance of the original French standard airworthiness certificate or the date of...

  20. 75 FR 12657 - Airworthiness Directives; The Boeing Company Model 777-200, -200LR, -300, -300ER, and 777F Series...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... operational program software for the autopilot flight director computers. This AD results from reports of rejected takeoffs at speeds above takeoff decision speed following inadvertent autopilot engagement on the... inadvertent engagement of the autopilot during takeoff roll, which could result in rejected takeoff...

  1. 75 FR 64633 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... also post a report summarizing each substantive verbal contact we receive about this AD. Costs of Compliance We estimate that this AD affects 354 airplanes of U.S. registry. This new AD adds no new costs to affected operators. The current costs for this AD are repeated for the convenience of affected...

  2. 78 FR 68986 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Aircraft Electronic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... maintenance of the airplane. The existing regulations and guidance material did not anticipate this type of... the safety and maintenance of the airplane. The existing regulations and guidance material did not... Series Airplanes; Aircraft Electronic System Security Protection From Unauthorized External Access...

  3. 76 FR 13534 - Airworthiness Directives; The Boeing Company Model 767-200, -300, -300F, and -400ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... explosion and consequent loss of the airplane. DATES: We must receive comments on this proposed AD by April... tanks, which, in combination with flammable fuel vapors, could result in a fuel tank explosion and... tanks, which, in combination with flammable fuel vapors, could result in a fuel tank explosion...

  4. 75 FR 15322 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... combination with flammable fuel vapors, could result in a center fuel tank explosion and consequent loss of... center fuel tank explosion and consequent loss of the airplane. Compliance (e) Comply with this AD...

  5. 77 FR 26663 - Airworthiness Directives; The Boeing Company Model 767-200, -300, -300F, and -400ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... inspections to detect cracking or corrosion of the fail-safe straps between the side fitting of the rear spar... applicability; and adds an inspection for cracking in the fail-safe strap, and repair or replacement if necessary. This AD was prompted by additional reports of cracks in 51 fail-safe straps on 41 airplanes;...

  6. 76 FR 22305 - Airworthiness Directives; The Boeing Company Model 777-200, -300, and -300ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ...) electronics units in certain power management panels; installing airplane information management system 2...) electronics units in certain power management panels; installing airplane information management system 2..., and installing power control circuitry for the center override/jettison and main jettison fuel...

  7. 78 FR 52107 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Rechargeable Lithium...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... Series Airplanes; Rechargeable Lithium Ion Batteries and Battery Systems AGENCY: Federal Aviation... lithium ion batteries and battery system that will be used on an International Communications Group (ICG... applied for a supplemental type certificate for installing equipment that uses rechargeable lithium...

  8. 78 FR 70849 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Aircraft Electronic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... with Class 3 Electronic Flight Bags (EFB) and wireless local area data networks (LAN) associated with the EFB architecture and existing airplane network systems. The applicable airworthiness regulations..., software-configurable avionics, and fiber-optic avionics networks. The proposed Class 3 EFB architecture...

  9. 78 FR 70848 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Aircraft Electronic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... with Class 3 Electronic Flight Bags (EFB) and wireless local area data networks (LAN) associated with the EFB architecture and existing airplane network systems. The applicable airworthiness regulations..., software-configurable avionics, and fiber-optic avionics networks. The proposed Class 3 EFB architecture...

  10. 75 FR 5677 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... corrosion of certain midspar fuse pins, and corrective actions if necessary. That AD also provides optional... to prevent loss of the strut and engine due to corrosion damage and cracking of both fuse pins on the... requires repetitive detailed and eddy current inspections to detect cracks and corrosion of certain...

  11. 75 FR 34663 - Airworthiness Directives; The Boeing Company Model 777-200, -300, and -300ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-18

    ... series airplanes. The original NPRM would have required installing Teflon sleeving under the clamps of... 3956). That original NPRM proposed to require installing Teflon sleeving under the clamps of the wire... for installing Teflon sleeving under the clamps of the power feeder wire bundles routed along...

  12. 76 FR 52899 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... after receipt. FOR FURTHER INFORMATION CONTACT: Ana Martinez Hueto, Aerospace Engineer, Cabin Safety and... district office. Related Information (i) For more information about this AD, contact Ana Martinez...

  13. 75 FR 82337 - Airworthiness Directives; The Boeing Company Model 777-200, -300, and -300ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    ... for the center override/jettison fuel pumps, and installing power control circuitry for the center ] override/jettison and main jettison fuel pumps. This proposed AD would also require installing new software... history of airplanes subject to those regulations, and existing maintenance practices for fuel...

  14. 75 FR 47180 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ...-pressure flex-hoses of the flightcrew and supernumerary oxygen system installed under the oxygen mask stowage box at flightcrew and supernumerary oxygen mask locations, and replacing the flex-hose with a new... flex-hoses of the flightcrew oxygen system that burned through due to inadvertent electrical...

  15. 75 FR 3656 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... oxygen system installed under the oxygen mask stowage box at a flightcrew and supernumerary oxygen mask... proposed AD results from reports of a low-pressure flex-hose of the flightcrew oxygen system that burned...-hoses used in the flightcrew and supernumerary oxygen systems to melt or burn, resulting in...

  16. 76 FR 13541 - Airworthiness Directives; The Boeing Company Model 757-200, -200CB, and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... target and the sensor proximity switch, and testing to ensure positive door locking and corrective action... relocating and adjusting the sensor target and the sensor proximity switch to forward locations on the... a new target and the switch is remounted on the new bracket. Boeing Service Bulletin...

  17. Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition.

    PubMed

    Haraguchi, Takeshi; Kondo, Masayuki; Uchikawa, Ryo; Kobayashi, Kazuyoshi; Hiramatsu, Hiroaki; Kobayashi, Kyousuke; Chit, Ung Weng; Shimizu, Takanobu; Iba, Hideo

    2016-02-18

    Whereas miR-200 family is known to be involved in the epithelial-to-mesenchymal transition (EMT), a crucial biological process observed in normal and pathological contexts, it has been largely unclear how far the functional levels of these tiny RNAs alone can propagate the molecular events to accomplish this process within several days. By developing a potent inhibitor of miR-200 family members (TuD-141/200c), the expression of which is strictly regulatable by the Tet (tetracycline)-On system, we found using a human colorectal cell line, HCT116, that several direct gene target mRNAs (Zeb1/Zeb2, ESRP1, FN1and FHOD1) of miR-200 family were elevated with distinct kinetics. Prompt induction of the transcriptional suppressors, Zeb1/Zeb2 in turn reduced the expression levels of miR-200c/-141 locus, EpCAM, ESRP1 and E-Cad. The loss of ESRP1 subsequently switched the splicing isoforms of CD44 and p120 catenin mRNAs to mesenchymal type. Importantly, within 9 days after the release from the inhibition of miR-200 family, all of the expression changes in the 14 genes observed in this study returned to their original levels in the epithelial cells. This suggests that the inherent epithelial plasticity is supported by a weak retention of key regulatory gene expression in either the epithelial or mesenchymal states through epigenetic regulation.

  18. Rabbit CD200R binds host CD200 but not CD200-like proteins from poxviruses

    PubMed Central

    Akkaya, Munir; Kwong, Lai-Shan; Akkaya, Erdem; Hatherley, Deborah; Barclay, A. Neil

    2016-01-01

    CD200 is a widely distributed membrane protein that gives inhibitory signals through its receptor (CD200R) on myeloid cells. CD200 has been acquired by herpesviruses where it has been shown to interact with host CD200R and downmodulate the immune system. It has been hypothesized that poxviruses have acquired CD200; but the potential orthologues show less similarity to their hosts. Myxoma virus M141 protein is a potential CD200 orthologue with a potent immune modulatory function in rabbits. Here, we characterized the rabbit CD200, CD200R and tested the CD200-like sequences for binding CD200R. No binding could be detected using soluble recombinant proteins, full length protein expressed on cells or myxoma virus infected cells. Finally, using knockdown models, we showed that the inhibitory effect of M141 on RAW 264.7 cells upon myxoma virus infection is not due to CD200R. We conclude that the rabbit poxvirus CD200-like proteins cause immunomodulation without utilizing CD200R. PMID:26590792

  19. 76 FR 24832 - Airworthiness Directives; Airbus Model A330-201, -202, -203, -223, and -243 Airplanes, A330-300...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-03

    ...-201, -202, -203, - 223, and -243 Airplanes, A330-300 Series Airplanes, A340-200 Series Airplanes, and A340-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... some rudders fitted on A330 and A340-200/-300 aeroplanes. An extended de-bonding, if not detected...

  20. 300 Junior Novel Anticipation Guides

    ERIC Educational Resources Information Center

    Polette, Nancy

    2006-01-01

    In this book, the author has created reproducible anticipation guides to 300 popular junior novels (grades 4-8) ranging from classics like Ben and Me and Cricket in Times Square to the current award winner, Kira, Kira. The book consists of 300 reproducible sets of open ended values questions to pique the interest of readers. Librarians and…

  1. Hanford 200 Areas Development Plan

    SciTech Connect

    Rinne, C.A.; Daly, K.S.

    1993-08-01

    The purpose of the Hanford 200 Areas Development Plan (Development Plan) is to guide the physical development of the 200 Areas (which refers to the 200 East Area, 200 West Area, and 200 Area Corridor, located between the 200 East and 200 West Areas) in accordance with US Department of Energy (DOE) Order 4320.lB (DOE 1991a) by performing the following: Establishing a land-use plan and setting land-use categories that meet the needs of existing and proposed activities. Coordinating existing, 5-year, and long-range development plans and guiding growth in accordance with those plans. Establishing development guidelines to encourage cost-effective development and minimize conflicts between adjacent activities. Identifying site development issues that need further analysis. Integrating program plans with development plans to ensure a logical progression of development. Coordinate DOE plans with other agencies [(i.e., Washington State Department of Ecology (Ecology) and US Environmental Protection Agency (EPA)]. Being a support document to the Hanford Site Development Plan (DOE-RL 1990a) (parent document) and providing technical site information relative to the 200 Areas.

  2. 50 CFR 300.11 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.11 Section 300.11... High Seas Fisheries § 300.11 Definitions. In addition to the terms defined in section 300.2 and those... following meanings. If a term is defined differently in § 300.2, the Act, or the Agreement, the...

  3. 50 CFR 300.101 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.101 Section 300.101... Antarctic Marine Living Resources § 300.101 Definitions. In addition to the terms defined in § 300.2, in the.... If a term is defined differently in § 300.2, such Act, or such Convention, the definition in...

  4. 50 CFR 300.151 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.151 Section 300.151.... Nationals Fishing in Russian Fisheries § 300.151 Definitions. In addition to the terms defined in § 300.2... is defined differently in § 300.2 or the Magnuson Act, the definition in this section shall...

  5. 50 CFR 300.61 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.61 Section 300.61... Pacific Halibut Fisheries § 300.61 Definitions. In addition to the terms defined in § 300.2 and those in... defined differently in § 300.2, the Act, or the Convention, the definition in this section shall...

  6. 34 CFR 300.709 - Public participation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Public participation. 300.709 Section 300.709 Education... Interior § 300.709 Public participation. In fulfilling the requirements of § 300.708 the Secretary of the Interior must provide for public participation consistent with § 300.165. (Authority: 20 U.S.C. 1411(h))...

  7. 34 CFR 300.709 - Public participation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Public participation. 300.709 Section 300.709 Education... Interior § 300.709 Public participation. In fulfilling the requirements of § 300.708 the Secretary of the Interior must provide for public participation consistent with § 300.165. (Authority: 20 U.S.C. 1411(h))...

  8. 34 CFR 300.709 - Public participation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Public participation. 300.709 Section 300.709 Education... Interior § 300.709 Public participation. In fulfilling the requirements of § 300.708 the Secretary of the Interior must provide for public participation consistent with § 300.165. (Authority: 20 U.S.C. 1411(h))...

  9. 34 CFR 300.709 - Public participation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Public participation. 300.709 Section 300.709 Education... Interior § 300.709 Public participation. In fulfilling the requirements of § 300.708 the Secretary of the Interior must provide for public participation consistent with § 300.165. (Authority: 20 U.S.C. 1411(h))...

  10. 34 CFR 300.709 - Public participation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Public participation. 300.709 Section 300.709 Education... Interior § 300.709 Public participation. In fulfilling the requirements of § 300.708 the Secretary of the Interior must provide for public participation consistent with § 300.165. (Authority: 20 U.S.C. 1411(h))...

  11. Catch tank inhibitor addition 200-East and 200-West Areas

    SciTech Connect

    Palit, A.N.

    1996-06-21

    Reported is the study of 11 catch tanks in the 200-East Area and the 7 catch tanks in the 200-West Area listed as active. The location, capacity, material of construction, annual total accumulation, annual rain intrusion, waste transfer rate, and access for chemical injection in these tanks are documented. The present and future utilization and isolation plans for the catch tanks are established.

  12. 76 FR 69685 - Airworthiness Directives; The Boeing Company Model 767-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-09

    ... information describes procedures for repetitive detailed inspections or surface high frequency eddy current... Airplanes Organization Designation Authorization (ODA) whom we have authorized to make those findings. Costs... estimate the following costs to comply with this proposed AD: Estimated Costs Cost on U.S. Action...

  13. 76 FR 53303 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... Airbus A330 ALI Document reference AI/SE-M4/95A.0089/97, which is approved by the European Aviation... given in Airbus A330 ALI Document reference AI/SE-M4/95A.0089/97, which is approved by the European... reference AI/SE-M4/95A.0089/97, which is approved by the European Aviation Safety Agency (EASA)...

  14. 76 FR 15867 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... proposed rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for the products listed above that would supersede an existing AD. This proposed AD results from mandatory... AD supersedes EASA AD 2009-0102 [and retains the requirements therein], and requires...

  15. Quarterly environmental radiological survey summary. Third quarter 1995 100, 200, 300, and 600 Areas

    SciTech Connect

    McKinney, S.M.; Markes, B.M.

    1995-09-01

    Routine radiological surveys are part of the near-facility environmental monitoring program which monitors and helps direct the reduction of the radiologically controlled areas at the Hanford Site. The routine radiological surveys are performed by the Southern Area Remediation Support Group and the Site Surveillance Radiological Control Group as directed by Near-Field Monitoring. The surveys included in this program consist of inactive waste sites; outdoor radiological control areas; tank farm perimeters and associated diversion boxes, lift stations, and vent stations; perimeters of active or uncovered waste sites such as burial grounds, retention basins, ponds, process trenches, and ditches; and road and rail surfaces. This report provides a summary of the radiological surveys performed during the Third Quarter of 1995. The status of corrective actions required from current and past reports are also discussed.

  16. 76 FR 68366 - Airworthiness Directives; The Boeing Company Model 777-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ... new bonding jumpers, and measuring the resistance of the modified installation to verify resistance is..., and measuring the resistance of the modified installation to verify resistance is within specified... new bonding jumpers, and do resistance measurements of the modified installation to verify...

  17. 75 FR 38945 - Airworthiness Directives; The Boeing Company Model 777-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ... electrical systems through a switch in the flight compartment in the event of smoke or flames. In the event... in order to minimize the risk of smoke or flames in the passenger cabin, a switch is needed in the... proposing this AD to minimize the risk of smoke or flames in the passenger cabin by installing a switch...

  18. 76 FR 12617 - Airworthiness Directives; The Boeing Company Model 777-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ...-essential electrical systems through a switch in the flight compartment in the event of smoke or flames. In... passenger cabin, a switch is needed in the flight compartment to enable the flightcrew to turn off... two new cabin power control switches. Boeing Service Bulletin 777-24-0074, Revision 1, dated October...

  19. 76 FR 37255 - Airworthiness Directives; Airbus Model A330-200 and -300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-27

    ... limitations applicable to the Certification Maintenance Requirements (CMR) are given in Airbus A330 ALS Part 3, which is approved by the European Aviation Safety Agency (EASA). The revision 03 of Airbus A330 ALS Part... Limitations Section (ALS). The airworthiness limitations applicable to the Certification...

  20. Quarterly Environmental Radiological Survey Summary Third Quarter 1998, 100, 200, 300, and 600 Areas

    SciTech Connect

    MCKINNEY, S.M.

    1998-10-27

    This report provides a summary of the radiological surveys performed in support of near-facility environmental monitoring at the Hanford Site. The Third Quarter 1998 survey results and the status of actions required are summarized: (1) All of the eighty-five environmental radiological surveys scheduled during July, August and September were performed as planned. Fifty-one of the surveys were conducted at Project Hanford Management Contractors (PHMC) sites and thirty-four at Environmental Restoration Contractor (ERC) sites. Contamination above background levels was found at seventeen of the PHMC waste sites and two of the ERC waste sites. Contamination levels as high >1,000,000 disintegrations per minute (dpm) per 100 cm{sup 2} were reported. Of these contaminated surveys nine were in Underground Radioactive Material (URM) areas, three were in unposted areas and seven were in contamination areas. The contamination found within four of the URM and three of the CA areas was immediately cleaned up and no further action was required. The remaining five URM and two unposted sites were posted and along with the five CA sites will require remediation. Radiological Problem Reports (RPR's) were issued and the sites were turned over to the landlord for further action as required. (2) During the second quarter of 1998, 1.2 hectares (3.0 acres) were stabilized and radiologically down posted from Contamination Area (CA)/Soil Contamination (SC) to URM. (3) Four hectares (10 acres) located south and west of B-Plant were posted as a radiological buffer area as a result of a contamination spread. This off-normal occurrence is currently being investigated. (4) Four Surveillance Compliance Inspection Reports (SCIRs) remained open and had not been resolved. Tank Farms Operations has responsibility for the unresolved SCIRs.

  1. 24 CFR 200.950 - Building product standards and certification program for solar water heating system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... certification program for solar water heating system. 200.950 Section 200.950 Housing and Urban Development... solar water heating system. (a) Applicable standards. (1) All solar water heating systems shall be...) Document OG-300-93, Operating Guidelines and Minimum Standards for Certifying Solar Water Heating...

  2. 24 CFR 200.950 - Building product standards and certification program for solar water heating system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... certification program for solar water heating system. 200.950 Section 200.950 Housing and Urban Development... solar water heating system. (a) Applicable standards. (1) All solar water heating systems shall be...) Document OG-300-93, Operating Guidelines and Minimum Standards for Certifying Solar Water Heating...

  3. 24 CFR 200.950 - Building product standards and certification program for solar water heating system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... certification program for solar water heating system. 200.950 Section 200.950 Housing and Urban Development... solar water heating system. (a) Applicable standards. (1) All solar water heating systems shall be...) Document OG-300-93, Operating Guidelines and Minimum Standards for Certifying Solar Water Heating...

  4. 49 CFR 173.300 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false 173.300 Section 173.300 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF...; Preparation and Packaging § 173.300...

  5. 48 CFR 7.300 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false 7.300 Section 7.300 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING ACQUISITION PLANNING Contractor Versus Government Performance 7.300...

  6. 50 CFR 300.66 - Prohibitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... §§ 300.63, 300.65, and 300.67. (c) Fish for halibut in Sitka Sound in violation of the Sitka Sound LAMP... possess subsistence halibut for commercial purposes; cause subsistence halibut to be sold, bartered,...

  7. 50 CFR 300.66 - Prohibitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... §§ 300.63, 300.65, and 300.67. (c) Fish for halibut in Sitka Sound in violation of the Sitka Sound LAMP... possess subsistence halibut for commercial purposes; cause subsistence halibut to be sold, bartered,...

  8. Quasi-cw 808-nm 300-W laser diode arrays

    NASA Astrophysics Data System (ADS)

    Bezotosnyi, V. V.; Kozyrev, A. A.; Kondakova, N. S.; Kondakov, S. A.; Krokhin, O. N.; Mikaelyan, G. T.; Oleshchenko, V. A.; Popov, Yu. M.; Cheshev, E. A.

    2017-02-01

    Samples of 808-nm quasi-cw laser diode arrays (LDAs) with an output power exceeding 300 W, a pulse duration of 200 μs, and a pulse repetition rate of 100 Hz are developed and fabricated. The main output parameters of a set of five LDAs, including light – current characteristics, current – voltage characteristics, and emission spectra are measured. Preliminary life tests show that the LDA power remains stable for 108 pulses.

  9. Ice core profiles of saturated fatty acids (C12:0-C30:0) and oleic acid (C18:1) from southern Alaska since 1734 AD: A link to climate change in the Northern Hemisphere

    NASA Astrophysics Data System (ADS)

    Pokhrel, Ambarish; Kawamura, Kimitaka; Seki, Osamu; Matoba, Sumio; Shiraiwa, Takayuki

    2015-01-01

    An ice core drilled at Aurora Peak in southeast Alaska was analyzed for homologous series of straight chain fatty acids (C12:0-C30:0) including unsaturated fatty acid (oleic acid) using gas chromatography (GC/FID) and GC/mass spectrometry (GC/MS). Molecular distributions of fatty acids are characterized by even carbon number predominance with a peak at palmitic acid (C16:0, av. 20.3 ± SD. 29.8 ng/g-ice) followed by oleic acid (C18:1, 19.6 ± 38.6 ng/g-ice) and myristic acid (C14:0, 15.3 ± 21.9 ng/g-ice). The historical trends of short-chain fatty acids, together with correlation analysis with inorganic ions and organic tracers suggest that short-chain fatty acids (except for C12:0 and C15:0) were mainly derived from sea surface micro layers through bubble bursting mechanism and transported over the glacier through the atmosphere. This atmospheric transport process is suggested to be linked with Kamchatka ice core δD record from Northeast Asia and Greenland Temperature Anomaly (GTA). In contrast, long-chain fatty acids (C20:0-C30:0) are originated from terrestrial higher plants, soil organic matter and dusts, which are also linked with GTA. Hence, this study suggests that Alaskan fatty acids are strongly influenced by Pacific Decadal Oscillation/North Pacific Gyre Oscillation and/or extra tropical North Pacific surface climate and Arctic oscillation. We also found that decadal scale variability of C18:1/C18:0 ratios in the Aurora Peak ice core correlate with the Kamchatka ice core δD, which reflects climate oscillations in the North Pacific. This study suggests that photochemical aging of organic aerosols could be controlled by climate periodicity.

  10. Preliminary Evaluation of PS300: A New Self-Lubricating High Temperature Composite Coating for Use to 800 C

    NASA Technical Reports Server (NTRS)

    Dellacorte, C.; Edmonds, B. J.

    1995-01-01

    This paper introduces PS300, a plasma sprayed, self-lubricating composite coating for use in sliding contacts at temperatures to 800 C. PS300 is a metal bonded chrome oxide coating with silver and BaF2/CaF2 eutectic solid lubricant additives. PS300 is similar to PS200, a chromium carbide based coating, which is currently being investigated for a variety of tribological applications. In pin-on-disk testing up to 650 C, PS300 exhibited comparable friction and wear properties to PS200. The PS300 matrix, which is predominantly chromium oxide rather than chromium carbide, does not require diamond grinding and polishes readily with silicon carbide abrasives greatly reducing manufacturing costs compared to PS200. It is anticipated that PS300 has potential for sliding bearing and seal applications in both aerospace and general industry.

  11. MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways.

    PubMed

    Li, X; Roslan, S; Johnstone, C N; Wright, J A; Bracken, C P; Anderson, M; Bert, A G; Selth, L A; Anderson, R L; Goodall, G J; Gregory, P A; Khew-Goodall, Y

    2014-07-31

    The microRNA-200 (miR-200) family has a critical role in regulating epithelial-mesenchymal transition and cancer cell invasion through inhibition of the E-cadherin transcriptional repressors ZEB1 and ZEB2. Recent studies have indicated that the miR-200 family may exert their effects at distinct stages in the metastatic process, with an overall effect of enhancing metastasis in a syngeneic mouse breast cancer model. We find in a xenograft orthotopic model of breast cancer metastasis that ectopic expression of members of the miR-200b/200c/429, but not the miR-141/200a, functional groups limits tumour cell invasion and metastasis. Despite modulation of the ZEB1-E-cadherin axis, restoration of ZEB1 in miR-200b-expressing cells was not able to alter metastatic potential suggesting that other targets contribute to this process. Instead, we found that miR-200b repressed several actin-associated genes, with the knockdown of the ezrin-radixin-moesin family member moesin alone phenocopying the repression of cell invasion by miR-200b. Moesin was verified to be directly targeted by miR-200b, and restoration of moesin in miR-200b-expressing cells was sufficient to alleviate metastatic repression. In breast cancer cell lines and patient samples, the expression of moesin significantly inversely correlated with miR-200 expression, and high levels of moesin were associated with poor relapse-free survival. These findings highlight the context-dependent effects of miR-200 in breast cancer metastasis and demonstrate the existence of a moesin-dependent pathway, distinct from the ZEB1-E-cadherin axis, through which miR-200 can regulate tumour cell plasticity and metastasis.

  12. 40 CFR 300.300 - Phase I-Discovery or notification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 28 2014-07-01 2014-07-01 false Phase I-Discovery or notification. 300.300 Section 300.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... CONTINGENCY PLAN Operational Response Phases for Oil Removal § 300.300 Phase I—Discovery or notification....

  13. 40 CFR 300.300 - Phase I-Discovery or notification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 28 2011-07-01 2011-07-01 false Phase I-Discovery or notification. 300.300 Section 300.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... CONTINGENCY PLAN Operational Response Phases for Oil Removal § 300.300 Phase I—Discovery or notification....

  14. 40 CFR 300.300 - Phase I-Discovery or notification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Phase I-Discovery or notification. 300.300 Section 300.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... CONTINGENCY PLAN Operational Response Phases for Oil Removal § 300.300 Phase I—Discovery or notification....

  15. 40 CFR 300.300 - Phase I-Discovery or notification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Phase I-Discovery or notification. 300.300 Section 300.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... CONTINGENCY PLAN Operational Response Phases for Oil Removal § 300.300 Phase I—Discovery or notification....

  16. 40 CFR 300.300 - Phase I-Discovery or notification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Phase I-Discovery or notification. 300.300 Section 300.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... CONTINGENCY PLAN Operational Response Phases for Oil Removal § 300.300 Phase I—Discovery or notification....

  17. Nuclear criticality safety: 300 Area

    SciTech Connect

    Not Available

    1991-07-31

    This Standard applies to the receipt, processing, storage, and shipment of fissionable material in the 300 Area and in any other facility under the control of the Reactor Materials Project Management Team (PMT). The objective is to establish practices and process conditions for the storage and handling of fissionable material that prevent the accidental assembly of a critical mass and that comply with DOE Orders as well as accepted industry practice.

  18. 16 CFR 300.16 - Ornamentation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Ornamentation. 300.16 Section 300.16... REGULATIONS UNDER THE WOOL PRODUCTS LABELING ACT OF 1939 Labeling § 300.16 Ornamentation. (a) Where the wool... § 300.23 of this part (Rule 23)....

  19. 46 CFR 148.300 - Radioactive materials.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Radioactive materials. 148.300 Section 148.300 Shipping... MATERIALS THAT REQUIRE SPECIAL HANDLING Special Requirements for Certain Materials § 148.300 Radioactive... surface, when averaged over an area of 300 cm2, does not exceed the following levels: (1) 4.0 Bq/cm2...

  20. 22 CFR 146.300 - Admission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Admission. 146.300 Section 146.300 Foreign... Recruitment Prohibited § 146.300 Admission. (a) General. No person shall, on the basis of sex, be denied admission, or be subjected to discrimination in admission, by any recipient to which §§ 146.300...

  1. 10 CFR 1042.300 - Admission.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Admission. 1042.300 Section 1042.300 Energy DEPARTMENT OF... Prohibited § 1042.300 Admission. (a) General. No person shall, on the basis of sex, be denied admission, or be subjected to discrimination in admission, by any recipient to which §§ 1042.300 through...

  2. 38 CFR 1.300 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Purpose. 1.300 Section 1.300 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Parking Fees at Va Medical Facilities § 1.300 Purpose. Sections 1.300 through 1.303 prescribe policies...

  3. 38 CFR 1.300 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Purpose. 1.300 Section 1.300 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Parking Fees at Va Medical Facilities § 1.300 Purpose. Sections 1.300 through 1.303 prescribe policies...

  4. 50 CFR 300.21 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Definitions. 300.21 Section 300.21 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Eastern Pacific Tuna Fisheries § 300.21 Definitions. In addition to the terms defined in § 300.2, in...

  5. 34 CFR 300.327 - Educational placements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Educational placements. 300.327 Section 300.327... Educational Placements Development of Iep § 300.327 Educational placements. Consistent with § 300.501(c), each... makes decisions on the educational placement of their child. (Authority: 20 U.S.C. 1414(e))...

  6. 34 CFR 300.327 - Educational placements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Educational placements. 300.327 Section 300.327... Educational Placements Development of Iep § 300.327 Educational placements. Consistent with § 300.501(c), each... makes decisions on the educational placement of their child. (Authority: 20 U.S.C. 1414(e))...

  7. 34 CFR 300.715 - Annual reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Annual reports. 300.715 Section 300.715 Education... Interior § 300.715 Annual reports. (a) In general. The advisory board established under § 300.714 must prepare and submit to the Secretary of the Interior and to Congress an annual report containing...

  8. 34 CFR 300.516 - Civil action.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Civil action. 300.516 Section 300.516 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.516 Civil action. (a... aggrieved by the findings and decision under § 300.514(b), has the right to bring a civil action...

  9. 50 CFR 300.301 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.301 Section 300.301 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Vessels on IUU Vessel Lists § 300.301 Definitions. In addition to the terms defined in § 300.2, the...

  10. 50 CFR 300.91 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.91 Section 300.91... Fraser River Sockeye and Pink Salmon Fisheries § 300.91 Definitions. In addition to the terms defined in.... If a term is defined differently in § 300.2, the Act, or the Treaty, the definition in this...

  11. 50 CFR 300.31 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.31 Section 300.31... South Pacific Tuna Fisheries § 300.31 Definitions. In addition to the terms defined in § 300.2, in the... definition in this section shall apply. Administrator means the individual or organization designated by...

  12. 50 CFR 300.21 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.21 Section 300.21... Pacific Tuna Fisheries § 300.21 Definitions. In addition to the terms defined in § 300.2, in the Act, and....2, in the Act, or in the Convention, the definition in this section shall apply. Bigeye tuna...

  13. 34 CFR 300.512 - Hearing rights.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Hearing rights. 300.512 Section 300.512 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.512 Hearing rights. (a....534, or an appeal conducted pursuant to § 300.514, has the right to— (1) Be accompanied and advised...

  14. 34 CFR 300.613 - Access rights.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Access rights. 300.613 Section 300.613 Education... § 300.613 Access rights. (a) Each participating agency must permit parents to inspect and review any... pursuant to § 300.510, and in no case more than 45 days after the request has been made. (b) The right...

  15. 34 CFR 300.516 - Civil action.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Civil action. 300.516 Section 300.516 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.516 Civil action. (a... aggrieved by the findings and decision under § 300.514(b), has the right to bring a civil action...

  16. Neutral Wind Observations below 200 km altitudes

    NASA Astrophysics Data System (ADS)

    Watanabe, S.; Abe, T.; Habu, H.; Kakinami, Y.; Larsen, M. F.; Pfaff, R. F., Jr.; Yamamoto, M.

    2015-12-01

    Neutral Wind Observations below 200 km altitudesS. Watanabe1, T. Abe2, H. Habu2, Y. Kakinami3, M. Larsen4, R. Pfaff5, M. Yamamoto6, M-Y. Yamamoto31Hokkaido University/Hokkaido Information University, 2JAXA/ISAS, 3Kochi University of Technology, 4Clemson University, 5NASA/Goddard Space Flight Center, 6Kyoto University, Neutral wind in the thermosphere is one of the key parameters to understand the ionosphere-thermosphere coupling process. JAXA/ISAS successfully launched sounding rockets from Uchinoura Space Center (USC) on September 2, 2007, January 12, 2012, and July 20, 2013, and NASA launched sounding rockets from Kwajalein on May 7, 2013 and from Wallops on July 4, 2013. The rockets installed Lithium and/or TMA canisters as well as instruments for plasma and electric and magnetic fields. The atomic Lithium gases were released at altitudes between 150 km and 300 km in the evening on September 2, 2007, at altitude of ~100 km in the morning on January 12, 2012, at altitude of ~120km in the midnight on July 20, 2013, at altitude between 150 km and 300 km in the evening on May 7, 2013 and at altitude of ~150 km in the noon on July 4, 2013. The Lithium atoms were scattering sunlight by resonance scattering with wavelength of 670nm. However, the Lithium atoms scattered moon light on July 20, 2013. The moon light scattering is the first time to use for thermospheric wind measurement in the midnight. The Lithium clouds/trails and TMA trails showed clearly the neutral wind shears and atmospheric waves at ~150 km altitude in the lower thermosphere for all local time.

  17. 38 CFR 20.300 - Rule 300. Place of filing Notice of Disagreement and Substantive Appeal.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Rule 300. Place of filing Notice of Disagreement and Substantive Appeal. 20.300 Section 20.300 Pensions, Bonuses, and Veterans... § 20.300 Rule 300. Place of filing Notice of Disagreement and Substantive Appeal. The Notice...

  18. 300 Area signal cable study

    SciTech Connect

    Whattam, J.W.

    1994-09-15

    This report was prepared to discuss the alternatives available for removing the 300 Area overhead signal cable system. This system, installed in 1969, has been used for various monitoring and communication signaling needs throughout the 300 Area. Over the years this cabling system has deteriorated, has been continually reconfigured, and has been poorly documented to the point of nonreliability. The first step was to look at the systems utilizing the overhead signal cable that are still required for operation. Of the ten systems that once operated via the signal cable, only five are still required; the civil defense evacuation alarms, the public address (PA) system, the criticality alarms, the Pacific Northwest Laboratory Facilities Management Control System (FMCS), and the 384 annunciator panel. Of these five, the criticality alarms and the FMCS have been dealt with under other proposals. Therefore, this study focused on the alternatives available for the remaining three systems (evacuation alarms, PA system, and 384 panel) plus the accountability aid phones. Once the systems to be discussed were determined, then three alternatives for providing the signaling pathway were examined for each system: (1) re-wire using underground communication ducts, (2) use the Integrated Voice/Data Telecommunications System (IVDTS) already installed and operated by US West, and (3) use radio control. Each alternative was developed with an estimated cost, advantages, and disadvantages. Finally, a recommendation was provided for the best alternative for each system.

  19. 50 CFR 300.17 - Reporting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the time limits required by the relevant regulations: (i) Antarctic—CCAMLR Logbook (50 CFR 300.107... CFR 300.22); or (vii) Western Pacific Purse Seine—South Pacific Tuna Treaty Logbook (50 CFR...

  20. VASIMR VX-200 thruster throttling optimization from 30 to 200 kW

    NASA Astrophysics Data System (ADS)

    Squire, Jared; Olsen, Chris; Chang-Diaz, Franklin; Longmier, Benjamin; Ballenger, Maxwell; Carter, Mark; Glover, Tim; McCaskill, Greg

    2012-10-01

    The VASIMR^ VX-200 experimental plasma thruster incorporates a 40 kW helicon plasma source with a 180 kW Ion Cyclotron Heating (ICH) acceleration stage integrated in a superconducting magnet. Argon propellant mass flow is injected up to 140 mg/s. Rapid plasma start up (< 100 ms) and high pumping speed (> 10^5 liters/s) in a 150 m^3 vacuum chamber achieve performance measurements with the charge exchange mean-free-path greater than 1 m in the background neutral gas (pressure < 10-5 Torr). The thruster efficiency at 200 kW total power is 72 ± 9%, the ratio of effective jet power to input RF power, with an Isp = 4900 ± 300 seconds (flow velocity of 49 km/s), and an ion flux of 1.7 ± 0.1 x 10^21/s. The thrust increases steadily with power to 5.8 ± 0.4 N until the power is maximized and there is no indication of saturation. The plasma density near the device exit exceeds 10^18 m-3 with a power density over 5 MW/m^2. An extensive study of thruster performance, efficiency and thrust-to-power ratio, as a function of Ar propellant flow rate and ICH-to-helicon RF power ratio has been carried out over a total power range of 30 to 200 kW. Optimized throttling set points are determined. The experimental configuration and results of this study are presented.

  1. OM300 Direction Drilling Module

    DOE Data Explorer

    MacGugan, Doug

    2013-08-22

    OM300 – Geothermal Direction Drilling Navigation Tool: Design and produce a prototype directional drilling navigation tool capable of high temperature operation in geothermal drilling Accuracies of 0.1° Inclination and Tool Face, 0.5° Azimuth Environmental Ruggedness typical of existing oil/gas drilling Multiple Selectable Sensor Ranges High accuracy for navigation, low bandwidth High G-range & bandwidth for Stick-Slip and Chirp detection Selectable serial data communications Reduce cost of drilling in high temperature Geothermal reservoirs Innovative aspects of project Honeywell MEMS* Vibrating Beam Accelerometers (VBA) APS Flux-gate Magnetometers Honeywell Silicon-On-Insulator (SOI) High-temperature electronics Rugged High-temperature capable package and assembly process

  2. 45 CFR 2555.300 - Admission.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Admission. 2555.300 Section 2555.300 Public... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 2555.300 Admission. (a) General. No..., by any recipient to which §§ 2555.300 through 2555.310 apply, except as provided in §§ 2555.225...

  3. 6 CFR 17.300 - Admission.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Admission. 17.300 Section 17.300 Domestic... in Admission and Recruitment Prohibited § 17.300 Admission. (a) General. No person shall, on the... which §§ 17.300 through 17.310 apply, except as provided in §§ 17.225 and 17.230. (b)...

  4. 40 CFR 5.300 - Admission.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Admission. 5.300 Section 5.300... in Admission and Recruitment Prohibited § 5.300 Admission. (a) General. No person shall, on the basis... which §§ 5.300 through §§ 5.310 apply, except as provided in §§ 5.225 and 5.230. (b)...

  5. 15 CFR 8a.300 - Admission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Admission. 8a.300 Section 8a.300... in Admission and Recruitment Prohibited § 8a.300 Admission. (a) General. No person shall, on the... which §§ 8a.300 through §§ 8a.310 apply, except as provided in §§ 8a.225 and §§ 8a.230. (b)...

  6. 45 CFR 2555.300 - Admission.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Admission. 2555.300 Section 2555.300 Public... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 2555.300 Admission. (a) General. No..., by any recipient to which §§ 2555.300 through 2555.310 apply, except as provided in §§ 2555.225...

  7. 14 CFR 1253.300 - Admission.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Admission. 1253.300 Section 1253.300... in Admission and Recruitment Prohibited § 1253.300 Admission. (a) General. No person shall, on the... which §§ 1253.300 through §§ 1253.310 apply, except as provided in §§ 1253.225 and §§ 1253.230....

  8. Viscosity of multi-component molten nitrate salts : liquidus to 200 degrees C.

    SciTech Connect

    Bradshaw, Robert W.

    2010-03-01

    The viscosity of molten salts comprising ternary and quaternary mixtures of the nitrates of sodium, potassium, lithium and calcium was determined experimentally. Viscosity was measured over the temperature range from near the relatively low liquidus temperatures of he individual mixtures to 200C. Molten salt mixtures that do not contain calcium nitrate exhibited relatively low viscosity and an Arrhenius temperature dependence. Molten salt mixtures that contained calcium nitrate were relatively more viscous and viscosity increased as the roportion of calcium nitrate increased. The temperature dependence of viscosity of molten salts containing calcium nitrate displayed curvature, rather than linearity, when plotted in Arrhenius format. Viscosity data for these mixtures were correlated by the Vogel-Fulcher- ammann-Hesse equation.

  9. Minus 55 to plus 200 deg C 12 bit analog-to-digital converter

    NASA Technical Reports Server (NTRS)

    Smith, L. R.; Prazak, P. R.

    1981-01-01

    A 12 bit successive approximation analog to digital converter that offers moderately high speed precision data conversion at a reasonable level of cost and complexity is studied. The ADCH10HT extends this capability over a temperature range of -55 to +200 C. No missing-code performance is maintained over the entire temperature range. The converter is completely self-contained with internal clock and +10 volt reference. The CMOS devices offer low power dissipation, so that the internal temperature of the hybrid circuit does not rise as much from self heating. In CMOS circuits, pn junction leakage currents are returned to the supplies so that the logic keeps working at temperatures up to 250 C.

  10. 24 CFR 300.9 - Office.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Office. 300.9 Section 300.9 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.9 Office....

  11. 24 CFR 300.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Exceptions. 300.15 Section 300.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.15 Exceptions....

  12. 24 CFR 300.9 - Office.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Office. 300.9 Section 300.9 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.9 Office....

  13. 24 CFR 300.3 - Description.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Description. 300.3 Section 300.3 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.3 Description....

  14. 24 CFR 300.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Exceptions. 300.15 Section 300.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.15 Exceptions....

  15. 24 CFR 300.3 - Description.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Description. 300.3 Section 300.3 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.3 Description....

  16. 45 CFR 2541.300 - Changes.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Changes. 2541.300 Section 2541.300 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE UNIFORM..., Property and Subawards § 2541.300 Changes. (a) General. Grantees and subgrantees are permitted to re...

  17. 31 CFR 1025.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1025.300 Section 1025.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Insurance Companies § 1025.300 General. Insurance companies are subject to the reporting requirements...

  18. 22 CFR 229.300 - Admission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Admission. 229.300 Section 229.300 Foreign... and Recruitment Prohibited § 229.300 Admission. (a) General. No person shall, on the basis of sex, be denied admission, or be subjected to discrimination in admission, by any recipient to which §§...

  19. 7 CFR 900.300 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false General. 900.300 Section 900.300 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... to Agricultural Marketing Agreement Act of 1937, as Amended § 900.300 General. Unless...

  20. 42 CFR 455.300 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Purpose. 455.300 Section 455.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... Hospital Payment Adjustments § 455.300 Purpose. This subpart implements Section 1923(j)(2) of the Act....

  1. 9 CFR 318.300 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Definitions. 318.300 Section 318.300 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... Products § 318.300 Definitions. (a) Abnormal container. A container with any sign of swelling or...

  2. 17 CFR 201.300 - Hearings.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Hearings. 201.300 Section 201.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES OF PRACTICE Rules of Practice Rules Regarding Hearings § 201.300 Hearings. Hearings for the purpose of taking evidence shall...

  3. 49 CFR 172.300 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Applicability. 172.300 Section 172.300 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... SECURITY PLANS Marking § 172.300 Applicability. (a) Each person who offers a hazardous material...

  4. 50 CFR 300.4 - General prohibitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false General prohibitions. 300.4 Section 300.4 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS General § 300.4 General prohibitions. It is unlawful for any person subject to the jurisdiction of...

  5. 18 CFR 1317.300 - Admission.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Admission. 1317.300 Section 1317.300 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY NONDISCRIMINATION ON... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 1317.300 Admission. (a) General....

  6. 31 CFR 1026.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1026.300 Section 1026.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Commodities § 1026.300 General. Futures commission merchants and introducing brokers in commodities...

  7. 14 CFR 1216.300 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Scope. 1216.300 Section 1216.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION ENVIRONMENTAL QUALITY Procedures for Implementing the National Environmental Policy Act (NEPA) § 1216.300 Scope. This subpart sets forth...

  8. 7 CFR 900.300 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false General. 900.300 Section 900.300 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... to Agricultural Marketing Agreement Act of 1937, as Amended § 900.300 General. Unless...

  9. 24 CFR 1003.300 - Application requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Application requirements. 1003.300 Section 1003.300 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT... Grant Application and Selection Process § 1003.300 Application requirements. (a) Application...

  10. 31 CFR 1029.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1029.300 Section 1029.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Made by Loan or Finance Companies § 1029.300 General. Loan or finance companies are subject to...

  11. 31 CFR 1023.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1023.300 Section 1023.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Be Made By Brokers or Dealers in Securities § 1023.300 General. Brokers or dealers in securities...

  12. 24 CFR 891.300 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Applicability. 891.300 Section 891.300 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED... for Persons With Disabilities § 891.300 Applicability. The requirements set forth in this subpart...

  13. 37 CFR 42.300 - Procedure; pendency.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Procedure; pendency. 42.300 Section 42.300 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT... Business Method Patents § 42.300 Procedure; pendency. (a) A covered business method patent review is...

  14. 18 CFR 1317.300 - Admission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Admission. 1317.300 Section 1317.300 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY NONDISCRIMINATION ON... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 1317.300 Admission. (a) General....

  15. 9 CFR 300.2 - FSIS responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false FSIS responsibilities. 300.2 Section 300.2 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION AGENCY MISSION AND ORGANIZATION § 300.2 FSIS responsibilities. (a) Delegations of authority....

  16. 42 CFR 440.300 - Basis.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis. 440.300 Section 440.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL....300 Basis. This subpart implements section 1937 of the Act, which authorizes States to provide...

  17. 31 CFR 1022.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1022.300 Section 1022.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Made By Money Services Businesses § 1022.300 General. Money services businesses are subject to...

  18. 31 CFR 1023.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1023.300 Section 1023.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Be Made By Brokers or Dealers in Securities § 1023.300 General. Brokers or dealers in securities...

  19. 48 CFR 927.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false General. 927.300 Section 927.300 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 927.300 General. (a) One of...

  20. 31 CFR 1024.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1024.300 Section 1024.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Funds § 1024.300 General. Mutual funds are subject to the reporting requirements set forth and...

  1. 16 CFR 300.1 - Terms defined.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Terms defined. 300.1 Section 300.1 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE WOOL PRODUCTS LABELING ACT OF 1939 Definitions § 300.1 Terms defined. (a) The term...

  2. 31 CFR 1028.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1028.300 Section 1028.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Be Made by Operators of Credit Card Systems § 1028.300 General. Operators of credit card systems...

  3. 7 CFR 94.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false General. 94.300 Section 94.300 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections... AND EGG PRODUCTS Processed Poultry Products § 94.300 General. Laboratory services of processed...

  4. 32 CFR 22.300 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Purpose. 22.300 Section 22.300 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-AWARD AND ADMINISTRATION Competition § 22.300 Purpose. This subpart establishes DoD policy...

  5. 24 CFR 570.300 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true General. 570.300 Section 570.300 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... COMMUNITY FACILITIES COMMUNITY DEVELOPMENT BLOCK GRANTS Entitlement Grants § 570.300 General. This...

  6. 46 CFR 116.300 - Structural design.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Structural design. 116.300 Section 116.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... Structure § 116.300 Structural design. Except as otherwise allowed by this subpart, a vessel must...

  7. 38 CFR 23.300 - Admission.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Admission. 23.300 Section 23.300 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 23.300 Admission. (a) General....

  8. 12 CFR 308.300 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Scope. 308.300 Section 308.300 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND... Safety and Soundness Deficiencies § 308.300 Scope. The rules and procedures set forth in this...

  9. 7 CFR 60.300 - Labeling.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Labeling. 60.300 Section 60.300 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... FOR FISH AND SHELLFISH General Provisions Country of Origin Notification § 60.300 Labeling....

  10. 33 CFR 143.300 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Applicability. 143.300 Section 143.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Vessels § 143.300 Applicability. This subpart applies to...

  11. 45 CFR 160.300 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Applicability. 160.300 Section 160.300 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Compliance and Investigations § 160.300 Applicability. This...

  12. 32 CFR 22.300 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Purpose. 22.300 Section 22.300 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-AWARD AND ADMINISTRATION Competition § 22.300 Purpose. This subpart establishes DoD policy...

  13. 31 CFR 1025.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1025.300 Section 1025.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Insurance Companies § 1025.300 General. Insurance companies are subject to the reporting requirements...

  14. 9 CFR 93.300 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Definitions. 93.300 Section 93.300 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.300 Definitions. Wherever in this subpart the following...

  15. 21 CFR 137.300 - Farina.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Farina. 137.300 Section 137.300 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... Related Products § 137.300 Farina. (a) Farina is the food prepared by grinding and bolting cleaned...

  16. 7 CFR 59.300 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Definitions. 59.300 Section 59.300 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... REPORTING Lamb Reporting § 59.300 Definitions. The following definitions apply to this subpart. Boxed...

  17. 31 CFR 1022.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1022.300 Section 1022.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Made By Money Services Businesses § 1022.300 General. Money services businesses are subject to...

  18. 14 CFR 1212.300 - Requesting amendment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Requesting amendment. 1212.300 Section 1212.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Amendments to Privacy Act Records § 1212.300 Requesting amendment. Individuals may request that NASA...

  19. 14 CFR 1259.300 - Description.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Description. 1259.300 Section 1259.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NATIONAL SPACE GRANT COLLEGE AND FELLOWSHIP PROGRAM National Needs Grants § 1259.300 Description. National needs awards may be awarded by...

  20. 31 CFR 1029.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1029.300 Section 1029.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Made by Loan or Finance Companies § 1029.300 General. Loan or finance companies are subject to...

  1. 40 CFR 63.300 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Applicability. 63.300 Section 63.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Oven Batteries § 63.300 Applicability. (a) Unless otherwise specified in §§ 63.306, 63.307, and...

  2. 42 CFR 436.300 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Scope. 436.300 Section 436.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... Medically Needy § 436.300 Scope. This subpart specifies the option for coverage of medically...

  3. 15 CFR 270.300 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Scope. 270.300 Section 270.300 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF...; and Protection of Information § 270.300 Scope. During the course of an investigation...

  4. 45 CFR 2541.300 - Changes.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Changes. 2541.300 Section 2541.300 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE UNIFORM..., Property and Subawards § 2541.300 Changes. (a) General. Grantees and subgrantees are permitted to re...

  5. 31 CFR 1021.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1021.300 Section 1021.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... By Casinos and Card Clubs § 1021.300 General. Casinos and card clubs are subject to the...

  6. 42 CFR 433.300 - Basis.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basis. 433.300 Section 433.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... Providers § 433.300 Basis. This subpart implements— (a) Section 1903(d)(2)(A) of the Act, which directs...

  7. 14 CFR 1209.300 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Scope. 1209.300 Section 1209.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION BOARDS AND COMMITTEES Contract Adjustment Board § 1209.300 Scope. This subpart continues in effect the Contract Adjustment Board...

  8. 50 CFR 300.10 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Purpose. 300.10 Section 300.10 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS High Seas Fisheries § 300.10 Purpose. This subpart implements the High Seas Fishing Compliance Act of...

  9. 40 CFR 80.300 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false 80.300 Section 80.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Abt Program-Baseline Determination § 80.300 ABT Program—Credit Generation...

  10. 31 CFR 1021.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1021.300 Section 1021.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... By Casinos and Card Clubs § 1021.300 General. Casinos and card clubs are subject to the...

  11. 9 CFR 300.1 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Purpose. 300.1 Section 300.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION... CERTIFICATION AGENCY MISSION AND ORGANIZATION § 300.1 Purpose. This part describes the duties and...

  12. 46 CFR 197.300 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Applicability. 197.300 Section 197.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE OCCUPATIONAL SAFETY AND HEALTH STANDARDS GENERAL PROVISIONS Commercial Diving Operations Equipment § 197.300 Applicability. (a) Each...

  13. 9 CFR 300.2 - FSIS responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false FSIS responsibilities. 300.2 Section 300.2 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION AGENCY MISSION AND ORGANIZATION § 300.2 FSIS responsibilities. (a) Delegations of authority....

  14. 14 CFR 1251.300 - Discrimination prohibited.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Discrimination prohibited. 1251.300 Section 1251.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP Accessibility § 1251.300 Discrimination prohibited. No qualified handicapped person...

  15. 31 CFR 1026.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1026.300 Section 1026.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Commodities § 1026.300 General. Futures commission merchants and introducing brokers in commodities...

  16. 16 CFR 300.2 - General requirement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false General requirement. 300.2 Section 300.2 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE WOOL PRODUCTS LABELING ACT OF 1939 Labeling § 300.2 General requirement. Each and...

  17. 9 CFR 381.300 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Definitions. 381.300 Section 381.300 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Canning and Canned Products § 381.300 Definitions....

  18. 22 CFR 229.300 - Admission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Admission. 229.300 Section 229.300 Foreign... and Recruitment Prohibited § 229.300 Admission. (a) General. No person shall, on the basis of sex, be denied admission, or be subjected to discrimination in admission, by any recipient to which §§...

  19. 42 CFR 400.300 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Scope. 400.300 Section 400.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS INTRODUCTION; DEFINITIONS OMB Control Numbers for Approved Collections of Information § 400.300 Scope....

  20. 33 CFR 158.300 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Purpose. 158.300 Section 158.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION RECEPTION...'s Facilities Are Adequate for Receiving NLS Residue § 158.300 Purpose. The purpose of this...

  1. 21 CFR 73.300 - Carrot oil.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Carrot oil. 73.300 Section 73.300 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.300 Carrot oil. (a) Identity. (1) The color additive...

  2. 18 CFR 1317.300 - Admission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Admission. 1317.300 Section 1317.300 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY NONDISCRIMINATION ON... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 1317.300 Admission. (a) General....

  3. 31 CFR 1030.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1030.300 Section 1030.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Required To Be Made by Housing Government Sponsored Enterprises § 1030.300 General. Housing...

  4. 46 CFR 174.300 - Specific applicability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Specific applicability. 174.300 Section 174.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO SPECIFIC VESSEL TYPES Hopper Dredges With Working Freeboard Assignments § 174.300...

  5. 42 CFR 435.300 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Scope. 435.300 Section 435.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... AMERICAN SAMOA Optional Coverage of the Medically Needy § 435.300 Scope. This subpart specifies the...

  6. 48 CFR 927.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false General. 927.300 Section 927.300 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 927.300 General. (a) One of...

  7. 49 CFR 173.300 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false [Reserved] 173.300 Section 173.300 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION... PACKAGINGS Gases; Preparation and Packaging § 173.300 [Reserved]...

  8. 7 CFR 63.300 - Establishment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Establishment. 63.300 Section 63.300 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... IMPROVEMENT CENTER General Provisions Revolving Fund § 63.300 Establishment. The NSIIC Revolving...

  9. 46 CFR 177.300 - Structural design.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Structural design. 177.300 Section 177.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) CONSTRUCTION AND ARRANGEMENT Hull Structure § 177.300 Structural design. Except as otherwise allowed by...

  10. 33 CFR 158.300 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Purpose. 158.300 Section 158.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION RECEPTION...'s Facilities Are Adequate for Receiving NLS Residue § 158.300 Purpose. The purpose of this...

  11. 42 CFR 435.300 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Scope. 435.300 Section 435.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... AMERICAN SAMOA Optional Coverage of the Medically Needy § 435.300 Scope. This subpart specifies the...

  12. 33 CFR 143.300 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Applicability. 143.300 Section 143.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Vessels § 143.300 Applicability. This subpart applies to...

  13. 40 CFR 761.300 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Applicability. 761.300 Section 761.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT...§ 761.61(a)(6) and Decontamination Under § 761.79(b)(3) § 761.300 Applicability. This subpart...

  14. 10 CFR 1015.300 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Scope. 1015.300 Section 1015.300 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES Standards for the Compromise of Claims § 1015.300 Scope. This subpart sets forth the standards for the compromise of claims under...

  15. 10 CFR 1021.300 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false General requirements. 1021.300 Section 1021.300 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES Implementing Procedures § 1021.300 General requirements. (a) DOE shall determine, under the procedures in...

  16. 31 CFR 1028.300 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false General. 1028.300 Section 1028.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Be Made by Operators of Credit Card Systems § 1028.300 General. Operators of credit card systems...

  17. 36 CFR 1211.300 - Admission.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Admission. 1211.300 Section 1211.300 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION GENERAL RULES... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 1211.300 Admission. (a) General....

  18. 42 CFR 433.300 - Basis.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Basis. 433.300 Section 433.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... Providers § 433.300 Basis. This subpart implements— (a) Section 1903(d)(2)(A) of the Act, which directs...

  19. 28 CFR 31.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false General. 31.300 Section 31.300 Judicial Administration DEPARTMENT OF JUSTICE OJJDP GRANT PROGRAMS Formula Grants Juvenile Justice Act Requirements § 31.300 General. This subpart sets forth specific JJDP Act requirements for application and receipt...

  20. 6 CFR 27.300 - Orders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Orders. 27.300 Section 27.300 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Orders and Adjudications § 27.300 Orders. (a) Orders Generally. When the Assistant Secretary determines...

  1. 33 CFR 143.300 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Applicability. 143.300 Section 143.300 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Vessels § 143.300 Applicability. This subpart applies to...

  2. 38 CFR 41.300 - Auditee responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Auditee responsibilities. 41.300 Section 41.300 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 41.300...

  3. 14 CFR 1206.300 - Exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Exemptions. 1206.300 Section 1206.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION AVAILABILITY OF AGENCY RECORDS TO MEMBERS OF THE PUBLIC Exemptions § 1206.300 Exemptions. (a) Under 5 U.S.C. 552(b) Agency records...

  4. 42 CFR 436.300 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Scope. 436.300 Section 436.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... Medically Needy § 436.300 Scope. This subpart specifies the option for coverage of medically...

  5. 45 CFR 400.300 - Waivers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Waivers. 400.300 Section 400.300 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND... § 400.300 Waivers. If a State wishes to apply for a waiver of a requirement of this part, the...

  6. 14 CFR 1203.300 - General.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false General. 1203.300 Section 1203.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.300 General. In general, the types of...

  7. 49 CFR 172.300 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Applicability. 172.300 Section 172.300 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... SECURITY PLANS Marking § 172.300 Applicability. (a) Each person who offers a hazardous material...

  8. 24 CFR 582.300 - General operation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true General operation. 582.300 Section 582.300 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... DEVELOPMENT COMMUNITY FACILITIES SHELTER PLUS CARE Program Requirements § 582.300 General operation....

  9. 46 CFR 181.300 - Fire pumps.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fire pumps. 181.300 Section 181.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) FIRE PROTECTION EQUIPMENT Fire Main System § 181.300 Fire pumps. (a) A self priming, power driven fire pump must...

  10. 31 CFR 1024.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false General. 1024.300 Section 1024.300 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FINANCIAL CRIMES... Funds § 1024.300 General. Mutual funds are subject to the reporting requirements set forth and...

  11. 25 CFR 11.300 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Complaints. 11.300 Section 11.300 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAW AND ORDER COURTS OF INDIAN OFFENSES AND LAW AND ORDER CODE Criminal Procedure § 11.300 Complaints. (a) A complaint is a written statement of the essential...

  12. 9 CFR 300.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Purpose. 300.1 Section 300.1 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION... CERTIFICATION AGENCY MISSION AND ORGANIZATION § 300.1 Purpose. This part describes the duties and...

  13. 10 CFR 800.300 - Loan servicing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Loan servicing. 800.300 Section 800.300 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loan Administration § 800.300 Loan servicing. (a) Servicing of a loan under...

  14. 50 CFR 300.222 - Prohibitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... with the sea turtle mitigation gear and handling requirements of § 300.223(f). (bb) Use a fishing... from a purse seine vessel at sea in the Convention Area, in contravention of § 300.216. (i) Fail to... seine gear to fish in an area closed under § 300.223(c). (y) Discard fish at sea in the ELAPS...

  15. 50 CFR 300.222 - Prohibitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...). (aa) Fail to comply with the sea turtle mitigation gear and handling requirements of § 300.223(f). (bb... from a purse seine vessel at sea in the Convention Area, in contravention of § 300.216. (i) Fail to... equipped with purse seine gear to fish in an area closed under § 300.223(c). (y) Discard fish at sea in...

  16. 50 CFR 300.222 - Prohibitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...). (aa) Fail to comply with the sea turtle mitigation gear and handling requirements of § 300.223(f). (bb... from a purse seine vessel at sea in the Convention Area, in contravention of § 300.216. (i) Fail to... equipped with purse seine gear to fish in an area closed under § 300.223(c). (y) Discard fish at sea in...

  17. 50 CFR 300.222 - Prohibitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... with the sea turtle mitigation gear and handling requirements of § 300.223(f). (bb) Use a fishing... from a purse seine vessel at sea in the Convention Area, in contravention of § 300.216. (i) Fail to... seine gear to fish in an area closed under § 300.223(c). (y) Discard fish at sea in the ELAPS...

  18. 40 CFR 300.335 - Funding.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 28 2014-07-01 2014-07-01 false Funding. 300.335 Section 300.335... Operational Response Phases for Oil Removal § 300.335 Funding. (a) The OSLTF is available under certain... timely response to a discharge of oil. (c) Procedures for funding the initiation of natural...

  19. 40 CFR 300.335 - Funding.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Funding. 300.335 Section 300.335... Operational Response Phases for Oil Removal § 300.335 Funding. (a) The OSLTF is available under certain... timely response to a discharge of oil. (c) Procedures for funding the initiation of natural...

  20. 40 CFR 300.335 - Funding.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 28 2011-07-01 2011-07-01 false Funding. 300.335 Section 300.335... Operational Response Phases for Oil Removal § 300.335 Funding. (a) The OSLTF is available under certain... timely response to a discharge of oil. (c) Procedures for funding the initiation of natural...

  1. 40 CFR 300.335 - Funding.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Funding. 300.335 Section 300.335... Operational Response Phases for Oil Removal § 300.335 Funding. (a) The OSLTF is available under certain... timely response to a discharge of oil. (c) Procedures for funding the initiation of natural...

  2. 34 CFR 300.29 - Native language.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Native language. 300.29 Section 300.29 Education... DISABILITIES General Definitions Used in This Part § 300.29 Native language. (a) Native language, when used with respect to an individual who is limited English proficient, means the following: (1) The...

  3. 34 CFR 300.29 - Native language.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Native language. 300.29 Section 300.29 Education... DISABILITIES General Definitions Used in This Part § 300.29 Native language. (a) Native language, when used with respect to an individual who is limited English proficient, means the following: (1) The...

  4. 34 CFR 300.29 - Native language.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Native language. 300.29 Section 300.29 Education... DISABILITIES General Definitions Used in This Part § 300.29 Native language. (a) Native language, when used with respect to an individual who is limited English proficient, means the following: (1) The...

  5. 34 CFR 300.29 - Native language.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Native language. 300.29 Section 300.29 Education... DISABILITIES General Definitions Used in This Part § 300.29 Native language. (a) Native language, when used with respect to an individual who is limited English proficient, means the following: (1) The...

  6. 34 CFR 300.29 - Native language.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Native language. 300.29 Section 300.29 Education... DISABILITIES General Definitions Used in This Part § 300.29 Native language. (a) Native language, when used with respect to an individual who is limited English proficient, means the following: (1) The...

  7. 34 CFR 300.16 - Excess costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Excess costs. 300.16 Section 300.16 Education... DISABILITIES General Definitions Used in This Part § 300.16 Excess costs. Excess costs means those costs that... for an example of how excess costs must be calculated.) (Authority: 20 U.S.C. 1401(8))...

  8. 34 CFR 300.16 - Excess costs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Excess costs. 300.16 Section 300.16 Education... DISABILITIES General Definitions Used in This Part § 300.16 Excess costs. Excess costs means those costs that... for an example of how excess costs must be calculated.) (Authority: 20 U.S.C. 1401(8))...

  9. 34 CFR 300.605 - Withholding funds.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Withholding funds. 300.605 Section 300.605 Education..., and Enforcement § 300.605 Withholding funds. (a) Opportunity for hearing. Prior to withholding any funds under Part B of the Act, the Secretary provides reasonable notice and an opportunity for a...

  10. 14 CFR 1203.300 - General.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false General. 1203.300 Section 1203.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.300 General. In general, the types of...

  11. 14 CFR 1203.300 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false General. 1203.300 Section 1203.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.300 General. In general, the types of...

  12. 14 CFR 1203.300 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true General. 1203.300 Section 1203.300 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Classification Principles and Considerations § 1203.300 General. In general, the types of...

  13. 40 CFR 82.300 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Purpose. 82.300 Section 82.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.300 Purpose....

  14. 40 CFR 82.300 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Purpose. 82.300 Section 82.300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.300 Purpose....

  15. 5 CFR 300.102 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Policy. 300.102 Section 300.102... Practices § 300.102 Policy. This subpart is directed to implementation of the policy that competitive... the relative capacity and fitness of candidates for the jobs to be filled; (b) Result in...

  16. 34 CFR 300.230 - SEA flexibility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true SEA flexibility. 300.230 Section 300.230 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility § 300.230 SEA flexibility. (a) Adjustment to State...

  17. 34 CFR 300.230 - SEA flexibility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false SEA flexibility. 300.230 Section 300.230 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility § 300.230 SEA flexibility. (a) Adjustment to State...

  18. 34 CFR 300.230 - SEA flexibility.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false SEA flexibility. 300.230 Section 300.230 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility § 300.230 SEA flexibility. (a) Adjustment to State...

  19. 34 CFR 300.230 - SEA flexibility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true SEA flexibility. 300.230 Section 300.230 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility § 300.230 SEA flexibility. (a) Adjustment to State...

  20. 34 CFR 300.230 - SEA flexibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false SEA flexibility. 300.230 Section 300.230 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES Local Educational Agency Eligibility § 300.230 SEA flexibility. (a) Adjustment to State...

  1. 6 CFR 27.300 - Orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Orders. 27.300 Section 27.300 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Orders and Adjudications § 27.300 Orders. (a) Orders Generally. When the Assistant Secretary determines...

  2. 34 CFR 300.642 - Data reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Data reporting. 300.642 Section 300.642 Education... § 300.642 Data reporting. (a) Protection of personally identifiable data. The data described in section... result in disclosure of data identifiable to individual children. (b) Sampling. The Secretary may...

  3. 34 CFR 300.642 - Data reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Data reporting. 300.642 Section 300.642 Education... § 300.642 Data reporting. (a) Protection of personally identifiable data. The data described in section... result in disclosure of data identifiable to individual children. (b) Sampling. The Secretary may...

  4. 34 CFR 300.642 - Data reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Data reporting. 300.642 Section 300.642 Education... § 300.642 Data reporting. (a) Protection of personally identifiable data. The data described in section... result in disclosure of data identifiable to individual children. (b) Sampling. The Secretary may...

  5. 34 CFR 300.642 - Data reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Data reporting. 300.642 Section 300.642 Education... § 300.642 Data reporting. (a) Protection of personally identifiable data. The data described in section... result in disclosure of data identifiable to individual children. (b) Sampling. The Secretary may...

  6. 34 CFR 300.642 - Data reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Data reporting. 300.642 Section 300.642 Education... § 300.642 Data reporting. (a) Protection of personally identifiable data. The data described in section... result in disclosure of data identifiable to individual children. (b) Sampling. The Secretary may...

  7. 34 CFR 300.517 - Attorneys' fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Attorneys' fees. 300.517 Section 300.517 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.517 Attorneys' fees... its discretion, may award reasonable attorneys' fees as part of the costs to— (i) The prevailing...

  8. 46 CFR 118.300 - Fire pumps.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Fire pumps. 118.300 Section 118.300 Shipping COAST GUARD... OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS FIRE PROTECTION EQUIPMENT Fire Main System § 118.300 Fire pumps. (a) A self priming, power driven fire pump must be installed on each vessel. (b) On...

  9. 46 CFR 181.300 - Fire pumps.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Fire pumps. 181.300 Section 181.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) FIRE PROTECTION EQUIPMENT Fire Main System § 181.300 Fire pumps. (a) A self priming, power driven fire pump must...

  10. 46 CFR 181.300 - Fire pumps.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Fire pumps. 181.300 Section 181.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) FIRE PROTECTION EQUIPMENT Fire Main System § 181.300 Fire pumps. (a) A self priming, power driven fire pump must...

  11. 46 CFR 118.300 - Fire pumps.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Fire pumps. 118.300 Section 118.300 Shipping COAST GUARD... OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS FIRE PROTECTION EQUIPMENT Fire Main System § 118.300 Fire pumps. (a) A self priming, power driven fire pump must be installed on each vessel. (b) On...

  12. 46 CFR 181.300 - Fire pumps.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Fire pumps. 181.300 Section 181.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) FIRE PROTECTION EQUIPMENT Fire Main System § 181.300 Fire pumps. (a) A self priming, power driven fire pump must...

  13. 46 CFR 118.300 - Fire pumps.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Fire pumps. 118.300 Section 118.300 Shipping COAST GUARD... OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS FIRE PROTECTION EQUIPMENT Fire Main System § 118.300 Fire pumps. (a) A self priming, power driven fire pump must be installed on each vessel. (b) On...

  14. 2 CFR 1.300 - OMB responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false OMB responsibilities. 1.300 Section 1.300 Grants and Agreements ABOUT TITLE 2 OF THE CODE OF FEDERAL REGULATIONS AND SUBTITLE A Responsibilities of OMB and Federal Agencies § 1.300 OMB responsibilities. OMB is responsible for: (a) Issuing...

  15. 50 CFR 300.106 - Exploratory fisheries.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Exploratory fisheries. 300.106 Section 300.106 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Antarctic Marine Living Resources § 300.106 Exploratory fisheries. (a) An exploratory fishery,...

  16. 50 CFR 300.106 - Exploratory fisheries.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Exploratory fisheries. 300.106 Section 300.106 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Antarctic Marine Living Resources § 300.106 Exploratory fisheries. (a) An exploratory fishery,...

  17. 50 CFR 300.106 - Exploratory fisheries.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Exploratory fisheries. 300.106 Section 300.106 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Antarctic Marine Living Resources § 300.106 Exploratory fisheries. (a) An exploratory fishery,...

  18. 50 CFR 300.106 - Exploratory fisheries.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Exploratory fisheries. 300.106 Section 300.106 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Antarctic Marine Living Resources § 300.106 Exploratory fisheries. (a) An exploratory fishery,...

  19. 50 CFR 300.106 - Exploratory fisheries.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Exploratory fisheries. 300.106 Section 300.106 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Antarctic Marine Living Resources § 300.106 Exploratory fisheries. (a) An exploratory fishery,...

  20. 50 CFR 300.37 - Radio monitoring.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182...

  1. 50 CFR 300.37 - Radio monitoring.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182...

  2. 50 CFR 300.37 - Radio monitoring.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182...

  3. 50 CFR 300.37 - Radio monitoring.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182...

  4. 50 CFR 300.37 - Radio monitoring.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182...

  5. 50 CFR 300.96 - Penalties.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Penalties. 300.96 Section 300.96 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.96 Penalties. Any treaty Indian who commits any act...

  6. 50 CFR 300.97 - Inseason orders.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Inseason orders. 300.97 Section 300.97 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.97 Inseason orders. (a) During the fishing...

  7. 50 CFR 300.96 - Penalties.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Penalties. 300.96 Section 300.96 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.96 Penalties. Any treaty Indian who commits any act...

  8. 50 CFR 300.96 - Penalties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Penalties. 300.96 Section 300.96 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.96 Penalties. Any treaty Indian who commits any act...

  9. 50 CFR 300.97 - Inseason orders.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Inseason orders. 300.97 Section 300.97 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.97 Inseason orders. (a) During the fishing...

  10. 50 CFR 300.96 - Penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Penalties. 300.96 Section 300.96 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.96 Penalties. Any treaty Indian who commits any act...

  11. 50 CFR 300.97 - Inseason orders.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Inseason orders. 300.97 Section 300.97 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.97 Inseason orders. (a) During the fishing...

  12. 50 CFR 300.96 - Penalties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Penalties. 300.96 Section 300.96 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.96 Penalties. Any treaty Indian who commits any act...

  13. 50 CFR 300.97 - Inseason orders.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Inseason orders. 300.97 Section 300.97 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Fraser River Sockeye and Pink Salmon Fisheries § 300.97 Inseason orders. (a) During the fishing...

  14. 21 CFR 73.300 - Carrot oil.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Carrot oil. 73.300 Section 73.300 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.300 Carrot oil. (a) Identity. (1) The color additive carrot... extraction of edible carrots (Daucus carota L.) with subsequent removal of the hexane by vacuum...

  15. 21 CFR 73.300 - Carrot oil.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Carrot oil. 73.300 Section 73.300 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.300 Carrot oil. (a) Identity. (1) The color additive carrot... extraction of edible carrots (Daucus carota L.) with subsequent removal of the hexane by vacuum...

  16. 21 CFR 73.300 - Carrot oil.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Carrot oil. 73.300 Section 73.300 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.300 Carrot oil. (a) Identity. (1) The color additive carrot... extraction of edible carrots (Daucus carota L.) with subsequent removal of the hexane by vacuum...

  17. 34 CFR 300.207 - Personnel development.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Personnel development. 300.207 Section 300.207 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility § 300.207 Personnel development. The...

  18. 34 CFR 300.519 - Surrogate parents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Surrogate parents. 300.519 Section 300.519 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.519 Surrogate parents... paragraph (a) of this section include the assignment of an individual to act as a surrogate for the...

  19. 34 CFR 300.519 - Surrogate parents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Surrogate parents. 300.519 Section 300.519 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.519 Surrogate parents... paragraph (a) of this section include the assignment of an individual to act as a surrogate for the...

  20. 34 CFR 300.519 - Surrogate parents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Surrogate parents. 300.519 Section 300.519 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.519 Surrogate parents... paragraph (a) of this section include the assignment of an individual to act as a surrogate for the...

  1. 34 CFR 300.519 - Surrogate parents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Surrogate parents. 300.519 Section 300.519 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.519 Surrogate parents... paragraph (a) of this section include the assignment of an individual to act as a surrogate for the...

  2. 34 CFR 300.519 - Surrogate parents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Surrogate parents. 300.519 Section 300.519 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.519 Surrogate parents... paragraph (a) of this section include the assignment of an individual to act as a surrogate for the...

  3. 34 CFR 300.505 - Electronic mail.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Electronic mail. 300.505 Section 300.505 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.505 Electronic mail. A....508 by an electronic mail communication, if the public agency makes that option available....

  4. 34 CFR 300.505 - Electronic mail.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Electronic mail. 300.505 Section 300.505 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.505 Electronic mail. A....508 by an electronic mail communication, if the public agency makes that option available....

  5. 34 CFR 300.505 - Electronic mail.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Electronic mail. 300.505 Section 300.505 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.505 Electronic mail. A....508 by an electronic mail communication, if the public agency makes that option available....

  6. 34 CFR 300.505 - Electronic mail.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Electronic mail. 300.505 Section 300.505 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.505 Electronic mail. A....508 by an electronic mail communication, if the public agency makes that option available....

  7. 50 CFR 300.40 - Civil penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Civil penalties. 300.40 Section 300.40... South Pacific Tuna Fisheries § 300.40 Civil penalties. The procedures of 15 CFR part 904 apply to the assessment of civil penalties, except as modified by the requirements of section 8 of the Act....

  8. 50 CFR 300.44 - Other inspections.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Other inspections. 300.44 Section 300.44... South Pacific Tuna Fisheries § 300.44 Other inspections. The operator and each member of the crew of any... photocopying, and to gather any other information relating to fisheries in the Licensing Area...

  9. 34 CFR 300.606 - Public attention.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Public attention. 300.606 Section 300.606 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND..., and Enforcement § 300.606 Public attention. Whenever a State receives notice that the Secretary...

  10. 6 CFR 27.300 - Orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Orders. 27.300 Section 27.300 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Orders and Adjudications § 27.300 Orders. (a) Orders Generally. When the Assistant Secretary determines...

  11. 6 CFR 27.300 - Orders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Orders. 27.300 Section 27.300 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Orders and Adjudications § 27.300 Orders. (a) Orders Generally. When the Assistant Secretary determines...

  12. 21 CFR 173.300 - Chlorine dioxide.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Chlorine dioxide. 173.300 Section 173.300 Food and... FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION Specific Usage Additives § 173.300 Chlorine dioxide. Chlorine dioxide (CAS Reg. No. 10049-04-4) may be safely used in food in accordance with...

  13. 21 CFR 173.300 - Chlorine dioxide.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Chlorine dioxide. 173.300 Section 173.300 Food and... Additives § 173.300 Chlorine dioxide. Chlorine dioxide (CAS Reg. No. 10049-04-4) may be safely used in food... the following methods: (i) Treating an aqueous solution of sodium chlorite with either chlorine gas...

  14. 21 CFR 173.300 - Chlorine dioxide.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Chlorine dioxide. 173.300 Section 173.300 Food and... Additives § 173.300 Chlorine dioxide. Chlorine dioxide (CAS Reg. No. 10049-04-4) may be safely used in food... the following methods: (i) Treating an aqueous solution of sodium chlorite with either chlorine gas...

  15. 21 CFR 173.300 - Chlorine dioxide.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Chlorine dioxide. 173.300 Section 173.300 Food and... Additives § 173.300 Chlorine dioxide. Chlorine dioxide (CAS Reg. No. 10049-04-4) may be safely used in food... the following methods: (i) Treating an aqueous solution of sodium chlorite with either chlorine gas...

  16. 21 CFR 173.300 - Chlorine dioxide.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Chlorine dioxide. 173.300 Section 173.300 Food and... Additives § 173.300 Chlorine dioxide. Chlorine dioxide (CAS Reg. No. 10049-04-4) may be safely used in food... the following methods: (i) Treating an aqueous solution of sodium chlorite with either chlorine gas...

  17. 50 CFR 300.171 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.171 Section 300.171 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Pacific Albacore Tuna Fisheries § 300.171 Definitions. In addition to the definitions in the...

  18. 50 CFR 300.201 - Definition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definition. 300.201 Section 300.201 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS Definition of Illegal, Unreported, or Unregulated Fishing § 300.201 Definition. Illegal, unreported,...

  19. 50 CFR 300.141 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.141 Section 300.141... United States-Canada Fisheries Enforcement § 300.141 Definitions. In addition to the terms defined in... definition in this section applies. Applicable Canadian fisheries law means any Canadian law, regulation...

  20. 50 CFR 300.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Definitions. 300.2 Section 300.2 Wildlife... § 300.2 Definitions. In addition to the definitions in each act, agreement, convention, or treaty... this definition. Fishing vessel means any vessel, boat, ship, or other craft that is used for,...