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Sample records for 238u-230th-226ra discussions sur

  1. 238U-230Th-226Ra disequilibria in plagioclase from recent mixed magmas at Mount Hood: constraints on crystal storage timescales and eruption triggering processes

    NASA Astrophysics Data System (ADS)

    Eppich, G. R.; Cooper, K. M.; Kent, A. J.; Koleszar, A. M.

    2010-12-01

    Uranium-series crystal ages, interpreted within a textural and geochemical framework, can provide insight into crystal storage timescales and eruption triggering processes. Mount Hood is a mixing-driven volcano that consistently erupts magmas of intermediate composition. Mixed magmas incorporate plagioclase derived from mafic and silicic end-member magmas (Kent AJR; Darr C; Koleszar AM; Salisbury MJ; Cooper KM. 2010. Preferential eruption of andesitic magmas through recharge filtering. Nature Geosci.). We measured 238U-230Th-226Ra disequilibria for four plagioclase size fractions, groundmass separates, and mafic inclusions from the Timberline (1500 a) and Old Maid (215 a) eruptive sequences. Measured (230Th)/(238U) was 1.126-1.143 for Timberline plagioclase and 1.127-1.143 for Old Maid plagioclase. Measured (226Ra)/(230Th) was 1.22-1.62 for Timberline plagioclase and 1.27-1.43 for Old Maid plagioclase. Corrections were performed for the presence of groundmass in the >500 µm plagioclase separates, and large plagioclase + groundmass in the <500 µm plagioclase separates. Small (<500 µm) plagioclase, derived from mafic magma, records enriched present-day (226Ra)/Ba relative to equilibrium with liquid proxies (groundmass and mafic inclusions), leading to undefined Ra-Th model ages. However, the measured disequilibria require that the majority of plagioclase in the separate is young (<<10 ka). Large (>500 µm) plagioclase, derived from the silicic mixing end-member, records (238U)/(230Th) disequilibrium and minor (226Ra)/(230Th) disequilibrium. Ra-Th model ages are 5-10 ka. Rims of large plagioclase crystallized within weeks of eruption (Kent et al., 2010), suggesting that the 5-10 ka Ra-Th model ages are averages of young rim growth and old cores, which could be >10 ka. Crystallization timescales of large plagioclase cores are longer than timescales of repose between eruptions, suggesting that the crystals must have been present yet remained untapped during older

  2. Mid-ocean ridge basalt generation along the slow-spreading, South Mid-Atlantic Ridge (5-11°S): Inferences from 238U-230Th-226Ra disequilibria

    NASA Astrophysics Data System (ADS)

    Turner, Simon; Kokfelt, Thomas; Hauff, Folkmar; Haase, Karsten; Lundstrom, Craig; Hoernle, Kaj; Yeo, Isobel; Devey, Colin

    2015-11-01

    U-series disequilibria have provided important constraints on the physical processes of partial melting that produce basaltic magma beneath mid-ocean ridges. Here we present the first 238U-230Th-226Ra isotope data for a suite of 83 basalts sampled between 5°S and 11°S along the South Mid-Atlantic Ridge. This section of the ridge can be divided into 5 segments (A0-A4) and the depths to the ridge axis span much of the global range, varying from 1429 to 4514 m. Previous work has also demonstrated that strong trace element and radiogenic isotope heterogeneity existed in the source regions of these basalts. Accordingly, this area provides an ideal location in which to investigate the effects of both inferred melt column length and recycled materials. 226Ra-230Th disequilibria indicate that the majority of the basalts are less than a few millennia old such that their 230Th values do not require any age correction. The U-Th isotope data span a significant range from secular equilibrium up to 32% 230Th excess, also similar to the global range, and vary from segment to segment. However, the (230Th/238U) ratios are not negatively correlated with axial depth and the samples with the largest 230Th excesses come from the deepest ridge segment (A1). Two sub-parallel and positively sloped arrays (for segments A0-2 and A3 and A4) between (230Th/238U) and Th/U ratios can be modelled in various ways as mixing between melts from peridotite and recycled mafic lithologies. Despite abundant evidence for source heterogeneity, there is no simple correlation between (230Th/238U) and radiogenic isotope ratios suggesting that at least some of the trace element and radiogenic isotope variability may have been imparted to the source regions >350 kyr prior to partial melting to produce the basalts. In our preferred model, the two (230Th/238U) versus Th/U arrays can be explained by mixing of melts from one or more recycled mafic lithologies with melts derived from chemically heterogeneous

  3. 238U-230Th-226Ra disequilibria in dacite and plagioclase from the 2004-2005 eruption of Mount St. Helens: Chapter 36 in A volcano rekindled: the renewed eruption of Mount St. Helens, 2004-2006

    USGS Publications Warehouse

    Cooper, Kari M.; Donnelly, Carrie T.; Sherrod, David R.; Scott, William E.; Stauffer, Peter H.

    2008-01-01

    230Th)/(232Th) measured for the 1980s reference suite. However, (230Th)/(232Th) for plagioclase separates for dome samples erupted during October and November 2004 are significantly different from corresponding whole-rock values, which suggests that a large fraction (>30 percent) of crystals in each sample are foreign to the host liquid. Furthermore, plagioclase in the two 2004 samples have U-series characteristics distinct from each other and from plagioclase in dacite erupted in 1982, indicating that (1) the current eruption must include a component of crystals (and potentially associated magma) that were not sampled by the 1980-86 eruption, and (2) dacite magmas erupted only a month apart in 2004 contain different populations of crystals, indicating that this foreign component is highly heterogeneous within the 2004-5 magma reservoir.

  4. Temporal and Petrogenetic Constraints on Volcanic Accretionary Processes at 9-10 Degrees North East Pacific Rise

    DTIC Science & Technology

    2010-06-01

    of ferrobasalts, basaltic andesites , andesites , and dacites sampled from the east limb of the overlapping spreading center at 9º03’N EPR is difficult...petrogenesis of dacites…………..212 4.6.7 238U-230Th-226Ra systematics among basaltic andesites and dacites…………………………………………………………..216 4.6.8... andesite and andesite compositions. Constant 87Sr/86Sr (~0.70250 ±50 ppm, 2σ) and near equilibrium (234U/238U) and (226Ra/230Th) isotopic compositions in

  5. DISCUSSION

    EPA Science Inventory

    This is an invited discussion of three invited papers on statistical disclosure limitation from the Second International Conference on Establishment Surveys, Buffalo, NY, June 2000. The three papers in this session deal with computing, estimates, and computing estimates in the c...

  6. Recent volcanic accretion at 9°N-10°N East Pacific Rise as resolved by combined geochemical and geological observations

    NASA Astrophysics Data System (ADS)

    Waters, C. L.; Sims, K. W. W.; Soule, S. A.; Blichert-Toft, J.; Dunbar, N. W.; Plank, T.; Prytulak, J.; Sohn, R. A.; Tivey, M. A.

    2013-08-01

    The ridge crest at 9°N-10°N East Pacific Rise (EPR) is dominated by overlapping lava flows that have overflowed the axial summit trough and flowed off-axis, forming a shingle-patterned terrain up to ˜2-4 km on either side of the axial summit trough. In this study, we employ 230Th-226Ra dating methods, in conjunction with geochemistry and seafloor geological observations, in an effort to discern the stratigraphic relationships between adjacent flows. We measured major and trace elements and 87Sr/86Sr, 143Nd/144Nd, 176Hf/177Hf, and 238U-230Th-226Ra for lava glass samples collected from several flow units up to ˜2 km away from the axial summit trough on the ridge crest at 9°50'N EPR. Statistical analysis of the 238U-230Th-226Ra data indicates that all but one measured sample from these flows cannot be resolved from the zero-age population; thus, we cannot confidently assign model ages to samples for discerning stratigraphic relationships among flows. However, because groups of samples can be distinguished based on similarities in geochemical compositions, particularly incompatible element abundances with high precision-normalized variability such as U and Th, and because the range of compositions is much greater than that represented by samples from the 1991-1992 and 2005-2006 eruptions, we suggest that the dive samples represent 6-10 eruptive units despite indistinguishable model ages. Geochemical variability between individual flows with similar ages requires relatively rapid changes in parental melt composition over the past ˜2 ka, and this likely reflects variations in the relative mixing proportions of depleted and enriched melts derived from a heterogeneous mantle source.

  7. Crystal Histories and Crustal Magmas: Insights into Magma Storage from U-Series Crystal Ages

    NASA Astrophysics Data System (ADS)

    Cooper, K. M.

    2014-12-01

    The dynamic processes operating within crustal magma reservoirs control many aspects of the chemical composition of erupted magmas, and crystals in volcanic rocks can provide a temporally-constrained archive of these changing environments. A new compilation of 238U-230Th ages of accessory phases and 238U-230Th-226Ra ages of bulk mineral separates of major phases documents that crystals in individual samples often have ages spanning most of the history of a volcanic center. Somewhat surprisingly, this observation holds for surface analyses as well as interior analyses, indicating that the latest stages of growth took place at different times for different grains. Nevertheless, average ages of surfaces are younger than interiors (as expected), and the dominant surface age population is often within error of eruption age. In contrast to accessory phase ages, less than half of the bulk separate 238U-230Th-226Ra ages for major phases are more than 10 kyr older than eruption. This suggests that major phases may in general reflect a later stage of development of an eruptible magma body than do accessory phases, or that the extent of discordance between ages of major and accessory phases reflects the extent to which a crystal mush was remobilized during processes leading to eruption. Crystal ages are most useful for illuminating magmatic processes when combined with crystal-scale trace-element or isotopic data, and I will present several case studies where such combined data sets exist. For example, at Yellowstone and at Okataina Caldera Complex, New Zealand, the combination zircon surface and interior analyses (of age, Hf isotopic, and trace-element data) with bulk dating and in-situ trace-element and isotopic compositions of feldspar allows a comparison of the early history of storage in a crystal mush with the later history of melt extraction and further crystallization prior to eruption, thus tracking development of erupted magma bodies from storage through eruption.

  8. Localised magmatic constraints on continental back-arc volcanism in southern Mendoza, Argentina: the Santa Maria Volcano

    NASA Astrophysics Data System (ADS)

    Espanon, Venera R.; Chivas, Allan R.; Turner, Simon P.; Kinsley, Leslie P. J.; Dosseto, Anthony

    2016-11-01

    The Payún Matrú Volcanic Field constitutes part of the continental back-arc in Argentina. This volcanic field has been the focus of several regional investigations; however, geochemical analysis of recent volcanoes (<8 ka) at the scale of an individual volcano has not been conducted. We present a morphological description for the Santa Maria Volcano in addition to results from major and trace element analysis and 238U-230Th-226Ra disequilibria. The trace element evidence suggests that the Santa Maria magmatic source has a composition similar to that of the local intraplate end member (resembling an ocean island basalt-like source), with a slight contribution from subduction-related material. The U-series analyses suggest a high 226Ra excess over 230Th for this volcano, which is not derived from a shallow process such as hydrothermal alteration or upper crustal contamination. Furthermore, intermediate-depth processes such as fractional crystallisation have been inferred for the Santa Maria Volcano, but they are not capable of producing the 226Ra excess measured. The 226Ra excess is explained by deep processes like partial melting of mantle lithologies with some influence from subducted Chilean trench sediments. Due to the short half-life of 226Ra (1600 years), we infer that fast magma ascent rates are required to preserve the high 226Ra excess.

  9. 210Pb-226Ra disequilibria in young gas-laden magmas

    PubMed Central

    Reagan, Mark; Turner, Simon; Handley, Heather; Turner, Michael; Beier, Christoph; Caulfield, John; Peate, David

    2017-01-01

    We present new 238U-230Th-226Ra-210Pb and supporting data for young lavas from southwest Pacific island arcs, Eyjafjallajökull, Iceland, and Terceira, Azores. The arc lavas have significant 238U and 226Ra excesses, whereas those from the ocean islands have moderate 230Th and 226Ra excesses, reflecting mantle melting in the presence of a water-rich fluid in the former and mantle melting by decompression in the latter. Differentiation to erupted compositions in both settings appears to have taken no longer than a few millennia. Variations in the (210Pb/226Ra)0 values in all settings largely result from degassing processes rather than mineral-melt partitioning. Like most other ocean island basalts, the Terceira basalt has a 210Pb deficit, which we attribute to ~8.5 years of steady 222Rn loss to a CO2-rich volatile phase while it traversed the crust. Lavas erupted from water-laden magma systems, including those investigated here, commonly have near equilibrium (210Pb/226Ra)0 values. Maintaining these equilibrium values requires minimal persistent loss or accumulation of 222Rn in a gas phase. We infer that degassing during decompression of water-saturated magmas either causes these magmas to crystallize and stall in reservoirs where they reside under conditions of near stasis, or to quickly rise towards the surface and erupt. PMID:28338093

  10. [Radiation risk assessment for plant reference species (Pinus sylvestris and Vicia cracca) from the area of radium production waste storage].

    PubMed

    Evseeva, T I; Geras'kin, S A; Belykh, E S; Maĭstrenko, T A; Vakhrusheva, O M

    2012-01-01

    The risk of an enhanced level of radionuclides of the uranium and thorium decay series in the environment for reference plant species (Pinus sylvestris and Vicia cracca) was assessed. 238U, 230Th, 226Ra, 210Po, 232Th and 228Th concentration factors for plants were found to be lower than one. The aboveground parts of Vicia cracca sampled from the area of the radium production waste storage mainly accumulated 22Ra, Pinus sylvestris branches--210Pb, 226Ra and 210Po. LOEDR calculated for the chromosome aberration frequency in both plant studies was 17-71 microGy/h. LOERD values for the reproductive capacity decrease in P. sylvestris and V. cracca were 17-71 microGy/h and 116-258 microGy/h, correspondingly. EDR10 for the chromosome aberration frequency in P. sylvestris and V. cracca were 148 and 347 microGy/h, that is, correspondingly, 255 and 708 times higher that background values. EDR10 for the plant reproductive capacity was 11-34 microGy/h, which 19-69 times increases the background values.

  11. Evolution of vegetation and soil nutrients after uranium mining in Los Ratones mine (Cáceres, Spain).

    PubMed

    Pérez-Fernández, María A; Vera-Tomé, Feliciano; Blanco-Rodríguez, María P; Lozano, Juan C

    2014-06-01

    The evolution of vegetation structure following mine rehabilitation is rather scarce in the literature. The concentration of long-lived radionuclides of the (238)U series might have harmful effects on living organisms. We studied soil properties and the natural vegetation occurring along a gradient in Los Ratones, an area rehabilitated after uranium mining located in Cáceres, Spain. Soil and vegetation were sampled seasonally and physical and chemical properties of soil were analysed, including natural isotopes of (238)U, (230)Th, (226)Ra and (210)Pb. Species richness, diversity, evenness and plant cover were estimated and correlated in relation to soil physical and chemical variables. The location of the sampling sites along a gradient had a strong explanatory effect on the herbaceous species, as well as the presence of shrubs and trees. Seasonal effects of the four natural isotopes were observed in species richness, species diversity and plant cover; these effects were directly related to the pH values in the soil, this being the soil property that most influences the plant distribution. Vegetation in the studied area resembles that of the surroundings, thus proving that the rehabilitation carried out in Los Ratones mine was successful in terms of understorey cover recovery.

  12. 210Pb-226Ra disequilibria in young gas-laden magmas

    NASA Astrophysics Data System (ADS)

    Reagan, Mark; Turner, Simon; Handley, Heather; Turner, Michael; Beier, Christoph; Caulfield, John; Peate, David

    2017-03-01

    We present new 238U-230Th-226Ra-210Pb and supporting data for young lavas from southwest Pacific island arcs, Eyjafjallajökull, Iceland, and Terceira, Azores. The arc lavas have significant 238U and 226Ra excesses, whereas those from the ocean islands have moderate 230Th and 226Ra excesses, reflecting mantle melting in the presence of a water-rich fluid in the former and mantle melting by decompression in the latter. Differentiation to erupted compositions in both settings appears to have taken no longer than a few millennia. Variations in the (210Pb/226Ra)0 values in all settings largely result from degassing processes rather than mineral-melt partitioning. Like most other ocean island basalts, the Terceira basalt has a 210Pb deficit, which we attribute to ~8.5 years of steady 222Rn loss to a CO2-rich volatile phase while it traversed the crust. Lavas erupted from water-laden magma systems, including those investigated here, commonly have near equilibrium (210Pb/226Ra)0 values. Maintaining these equilibrium values requires minimal persistent loss or accumulation of 222Rn in a gas phase. We infer that degassing during decompression of water-saturated magmas either causes these magmas to crystallize and stall in reservoirs where they reside under conditions of near stasis, or to quickly rise towards the surface and erupt.

  13. (210)Pb-(226)Ra disequilibria in young gas-laden magmas.

    PubMed

    Reagan, Mark; Turner, Simon; Handley, Heather; Turner, Michael; Beier, Christoph; Caulfield, John; Peate, David

    2017-03-24

    We present new (238)U-(230)Th-(226)Ra-(210)Pb and supporting data for young lavas from southwest Pacific island arcs, Eyjafjallajökull, Iceland, and Terceira, Azores. The arc lavas have significant (238)U and (226)Ra excesses, whereas those from the ocean islands have moderate (230)Th and (226)Ra excesses, reflecting mantle melting in the presence of a water-rich fluid in the former and mantle melting by decompression in the latter. Differentiation to erupted compositions in both settings appears to have taken no longer than a few millennia. Variations in the ((210)Pb/(226)Ra)0 values in all settings largely result from degassing processes rather than mineral-melt partitioning. Like most other ocean island basalts, the Terceira basalt has a (210)Pb deficit, which we attribute to ~8.5 years of steady (222)Rn loss to a CO2-rich volatile phase while it traversed the crust. Lavas erupted from water-laden magma systems, including those investigated here, commonly have near equilibrium ((210)Pb/(226)Ra)0 values. Maintaining these equilibrium values requires minimal persistent loss or accumulation of (222)Rn in a gas phase. We infer that degassing during decompression of water-saturated magmas either causes these magmas to crystallize and stall in reservoirs where they reside under conditions of near stasis, or to quickly rise towards the surface and erupt.

  14. Discussing discursive discussions.

    PubMed

    Walsh, Kieran

    2016-12-01

    Discussions are an important part of medical education research papers, but there is little guidance on how to write up the discussion section. A good discussion section should relate closely to the results; it should include a balanced review of the strengths and weaknesses of the study; it should be realistic in evaluating the applicability of the results; and it should mention the feasibility of widespread adoption of the intervention. This paper describes a review of the discussion sections of research papers published in Medical Education. The review led to further discussion. Common errors in writing discussion sections include: minimising the weaknesses of a study or exaggerating its strengths; closing down debate too early or opening up new arguments at too late a stage; and getting carried away by the potential of technology or getting very carried away by the potential of technology. Some discussions can be too long, but restricted word counts keep abstracts mercifully short. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

  15. Utilisation de traceurs radioactifs pour l'évaluation du recrutement des leucocytes et des échanges vasculaires au niveau d'organes in~vivo. Description d'une méthode et discussion des problèmes d'interprétation sur quelques exemples

    NASA Astrophysics Data System (ADS)

    Bureau, M. F.

    1997-03-01

    An experimental method using simultaneously different γ emiter tracers was developed to evaluate inflammation in vivo. Experiments were performed on the anaesthetized guinea-pig to test pulmonary effects of inflammatory agents. Red blood cells, albumin and inflammatory cells (platelets or leucocytes) radiolabelled with 99m technetium, 131 iodine and 111 indium respectively were injected i.v. Their radioactivities were measured on a pulmonary region by external detection and on blood samples in a well type counter. From these measurements variations of the lung contents in red blood cells, extravascular albumin and non circulating leucocytes during inflammatory stimulation were evaluated. These parameters axe indexes of blood perfusion, vascular exchanges and leucocyte sequestration respectively. Fiability of the method and meaning of the parameters evaluated are discussed. Une méthode expérimentale utilisant simultanément différents traceurs γ a été développée pour évaluer l'inflammation in vivo. Des expériences ont été réalisées chez le cobaye anesthésié pour tester l'effet pulmonaire d'agents inflammatoires. Des globules rouges, de l'albumine et des cellules inflammatoires (plaquettes ou leucocytes) radiomarqués respectivement au technetium 99m, à l'iode 131 et à l'indium 111 sont injectés i.v. Leurs radioactivités sont mesurées sur une région pulmonaire par détection externe et sur des échantillons sanguins au compteur puit. À partir de ces mesures sont évaluées les variations des contenus pulmonaires en globules rouges, en albumine extravasculaire et en leucocytes non circulants lors d'une stimulation inflammatoire. Ces paramètres sont corrélés aux modifications de la perfusion, des échanges vasculaires et de la séquestration leucocytaire. La fiabilité de la méthode et la signification des paramètres évalués sont discutées.

  16. Traditional medicine of Baja California Sur (Mexico). I.

    PubMed

    Dimayuga, R E; Agundez, J

    1986-08-01

    This study deals with the medicinal use of 30 plants collected in the Municipio de Los Cabos and part of the Municipio de la Paz, Baja California Sur, Mexico. The plants were all taxonomically identified at least to genus level, and their medicinal use, as described to us by elder people, is discussed.

  17. Antimicrobial screening of medicinal plants from Baja California Sur, Mexico.

    PubMed

    Encarnación Dimayuga, R; Keer Garcia, S

    1991-02-01

    The ethanolic extracts of 72 plants belonging to 35 different families, and used in traditional medicine in Baja California Sur (México), were tested for antimicrobial activity in vitro using the filter paper disk assay method. Activity against Staphylococcus aureus, Bacillus subtilis, Streptococcus faecalis (Gram-positive microorganisms), Escherichia coli (Gram-negative microorganisms) and Candida albicans (yeast) is discussed.

  18. Sill to surface: Linking young off-axis volcanism with subsurface melt at the overlapping spreading center at 9°03‧N East Pacific Rise

    NASA Astrophysics Data System (ADS)

    Waters, Christopher L.; Sims, Kenneth W. W.; Klein, Emily M.; White, Scott M.; Reagan, Mark K.; Girard, Guillaume

    2013-05-01

    No young, off-axis, mid-ocean ridge lavas have yet been directly linked to underlying off-axis melt bodies. In this study, we present new measurements of 238U-230Th-226Ra-210Pb isotope compositions for a suite of lavas from the overlapping spreading center (OSC) at 9°03'N on the East Pacific Rise (EPR). These lavas span a large range of compositions, from basalt to dacite, and include both axial and off-axis samples recovered from a prominent, axis-parallel pillow ridge and a flat-topped seamount that overlie the westernmost extent of a 4-km-wide melt lens (Kent et al., 2000). We report 210Pb excesses in axial basalts and basaltic andesites, which we suggest results from gas-magma fractionation of 222Rn from 226Ra beneath dacite magmas. In addition, our U-series ages agree with visual observations, indicating that while most recent volcanic activity occurs at the spreading axis, active volcanism also occurs away from the axis. Specifically, the off-axis pillow ridge and seamount samples overlying the off-axis subsurface melt body have eruption ages of less than 8 ka, and likely as young as 1 ka, despite being located on crust that has a spreading age of ~75 ka. The young ages of these lavas, combined with existing geological, geochemical and geophysical constraints, provide evidence for a genetic link between the pillow ridge and seamount lavas and the seismically imaged, underlying off-axis melt lens. This link demonstrates that off-axis volcanism does not necessarily come from a sub-axial magma body and can be sourced directly from off-axis magma bodies.

  19. Geochemical hosts of solubilized radionuclides in uranium mill tailings

    USGS Publications Warehouse

    Landa, E.R.; Bush, C.A.

    1990-01-01

    The solubilization and subsequent resorption of radionuclides by ore components or by reaction products during the milling of uranium ores may have both economic and environmental consequences. Particle-size redistribution of radium during milling has been demonstrated by previous investigators; however, the identification of sorbing components in the tailings has received little experimental attention. In this study, uranium-bearing sandstone ore was milled, on a laboratory scale, with sulfuric acid. At regular intervals, filtrate from this suspension was placed in contact with mixtures of quartz sand and various potential sorbents which occur as gangue in uranium ores; the potential sorbents included clay minerals, iron and aluminum oxides, feldspar, fluorspar, barite, jarosite, coal, and volcanic glass. After equilibration, the quartz sand-sorbent mixtures were separated from the filtrate and radioassayed by gamma-spectrometry to determine the quantities of 238U, 230Th, 226Ra, and 210Pb sorbed, and the radon emanation coefficients. Sorption of 238U was low in all cases, with maximal sorptions of 1-2% by the bentonite- and coal-bearing samples. 230Th sorption also was generally less than 1%; maximal sorption here was observed in the fluorspar-bearing sample and appears to be associated with the formation of gypsum during milling. 226Ra and 210 Pb generally showed higher sorption than the other nuclides - more than 60% of the 26Ra solubilized from the ore was sorbed on the barite-bearing sample. The mechanism (s) for this sorption by a wide variety of substrates is not yet understood. Radon emanation coefficients of the samples ranged from about 5 to 30%, with the coal-bearing samples clearly demonstrating an emanating power higher than any of the other materials. ?? 1990.

  20. U-series isotope systematics of mafic magmas from central Oregon: Implications for fluid involvement and melting processes in the Cascade arc

    NASA Astrophysics Data System (ADS)

    Mitchell, Euan C.; Asmerom, Yemane

    2011-12-01

    The Cascade arc is the warm-slab subduction zone global end member, where a broad variety of primitive magmas with highly variable slab fluid signatures have erupted in close spatial and temporal proximity. A number of petrogenetic models have been proposed to explain the occurrence of such diverse magmas, but the source(s) of these magmas and the timing of fluid addition to the sub-arc mantle remain controversial. We present uranium-series isotope data ( 238U- 230Th- 226Ra) for eighteen mafic lavas from the Three Sisters region of the central Oregon Cascades, and for a further six lavas from the rear-arc Newberry Volcano. The majority of these samples have geochemical characteristics (e.g. Nb/Zr, Ba/Zr, 87Sr/ 86Sr) consistent with previously described calc-alkaline basalts from this region of the arc, and indicative of limited fluid involvement at some stage in their genesis. Trace element and long-lived radiogenic isotope modeling suggests that this fluid was derived from dehydration of subducting sediments, and was added to an enriched, garnet-bearing mantle wedge source. The trace element systematics of the lavas are consistent with small degree (< 10%) melts of this fluid-modified source. All samples display ( 230Th/ 238U) and ( 226Ra/ 230Th) ≥ 1, similar to values measured in fresh MORB and other parts of the arc. Results of a dynamic melting model support the interpretation that these lavas are small degree melts of an asthenospheric source, and do not allow for a lithospheric mantle source. However, the U-series data do not permit us to determine whether fluid addition was the trigger for melting, or whether the lavas were generated from a secular equilibrium source that had experienced fluid addition > 350 ka prior to melting. Regardless, modern fluid input is limited and melting is dominantly occurring in response to upwelling and decompression.

  1. Timescales of storage and recycling of crystal mush at Krafla Volcano, Iceland

    NASA Astrophysics Data System (ADS)

    Cooper, Kari M.; Sims, Kenneth W. W.; Eiler, John M.; Banerjee, Neil

    2016-06-01

    Processes in upper-crustal magma reservoirs such as recharge, magma mixing, recycling of previously crystallized material, and eruption affect both the physical state and the chemical composition of magmas. A growing body of evidence shows that crystals in intermediate or silicic volcanic rocks preserve records of these processes that may be obscured due to mixing in the liquid fraction of magmas. Fewer studies have focused on crystals in basaltic lavas, but these show evidence for a more subtle, but still rich record of magmatic processes. We present new 238U-230Th-226Ra data for plagioclase, combined with δ18O and trace-element measurements of the same crystal populations, from basalts erupted at Krafla Volcanic Center, Iceland. These data document the presence of multiple crystal populations within each sample, with chemical and oxygen isotope heterogeneity at a variety of scales: within individual crystals, between crystals in a given population, between crystal populations within the same sample, and between crystals in lavas erupted from different vents during the same eruption. Comparison to whole-rock or groundmass data shows that the majority of macroscopic crystals are not in trace-element or oxygen isotope equilibrium with their host liquids. The most likely explanation for these data is that the macroscopic crystals originated within a highly heterogeneous crystal mush in the shallow magma reservoir system. U-series and diffusion data indicate that the crystals (and therefore the mush) formed recently (likely within a few thousand years of eruption, and with a maximum age of 8-9 ka), and that the crystals resided in their host magma prior to eruption for decades to a few centuries at most. These data, in conjunction with other recent studies, suggest a model where erupted Icelandic magmas are the result of diverse magmas entering the crust, followed by complex interactions between melts and previously crystallized material at all crustal levels.

  2. Isotopic constraints on the genesis and evolution of basanitic lavas at Haleakala, Island of Maui, Hawaii

    NASA Astrophysics Data System (ADS)

    Phillips, Erin H.; Sims, Kenneth W. W.; Sherrod, David R.; Salters, Vincent J. M.; Blusztajn, Jurek; Dulai, Henrietta

    2016-12-01

    To understand the dynamics of solid mantle upwelling and melting in the Hawaiian plume, we present new major and trace element data, Nd, Sr, Hf, and Pb isotopic compositions, and 238U-230Th-226Ra and 235U-231Pa-227Ac activities for 13 Haleakala Crater nepheline normative basanites with ages ranging from ∼900 to 4100 yr B.P. These basanites of the Hana Volcanics exhibit an enrichment in incompatible trace elements and a more depleted isotopic signature than similarly aged Hawaiian shield lavas from Kilauea and Mauna Loa. Here we posit that as the Pacific lithosphere beneath the active shield volcanoes moves away from the center of the Hawaiian plume, increased incorporation of an intrinsic depleted component with relatively low 206Pb/204Pb produces the source of the basanites of the Hana Volcanics. Haleakala Crater basanites have average (230Th/238U) of 1.23 (n = 13), average age-corrected (226Ra/230Th) of 1.25 (n = 13), and average (231Pa/235U) of 1.67 (n = 4), significantly higher than Kilauea and Mauna Loa tholeiites. U-series modeling shows that solid mantle upwelling velocity for Haleakala Crater basanites ranges from ∼0.7 to 1.0 cm/yr, compared to ∼10 to 20 cm/yr for tholeiites and ∼1 to 2 cm/yr for alkali basalts. These modeling results indicate that solid mantle upwelling rates and porosity of the melting zone are lower for Hana Volcanics basanites than for shield-stage tholeiites from Kilauea and Mauna Loa and alkali basalts from Hualalai. The melting rate, which is directly proportional to both the solid mantle upwelling rate and the degree of melting, is therefore greatest in the center of the Hawaiian plume and lower on its periphery. Our results indicate that solid mantle upwelling velocity is at least 10 times higher at the center of the plume than at its periphery under Haleakala.

  3. Rapid time scales of basalt to andesite differentiation at Anatahan volcano, Mariana Islands

    NASA Astrophysics Data System (ADS)

    Reagan, Mark; Tepley, Frank J.; Gill, James B.; Wortel, Matthew; Hartman, Brian

    2005-08-01

    We present comprehensive U-series data ( 238U- 234U- 230Th- 226Ra- 210Pb- 210Po and ( 230Th)/( 232Th)) for an andesite from an oceanic arc. The juvenile Anatahan andesite has U-Th systematics colinear with other historical Mariana volcanic rocks, and is most similar to those of the other volcano in the Mariana arc with a significant proportion of silicic andesite: Uracas. Like Uracas, the parental basalt for the Anatahan andesite was generated by relatively low degrees of flux melting from a source previously enriched in a sediment component from the subducting slab. However, the Anatahan andesite is much more strongly enriched in 226Ra over 230Th than Uracas lavas, and has one of the highest ( 226Ra)/( 232Th) ratios of siliceous andesites globally. The long-lived disequilibria between 238U- 230Th- 226Ra in the Anatahan andesite are inherited from basalt genesis, not created during differentiation or eruption. Thus, the time between genesis of the parental basalt and eruption of andesite at Anatahan is shorter than for Uracas. Moreover, the near-equilibrium ( 210Pb)/( 226Ra) value indicates that the magma body did not persistently lose or gain 222Rn for more than 2 years before eruption. This permits differentiation of the parental basalt to form andesite within this 2-year time period, although a differentiation time period between 100 and a few thousand years also is possible. The relative activities between 210Po and 210Pb suggest erupted scoria degassed Po less than most lavas despite eruption plume heights of ˜10 km, which further suggests an unusually rapid ascent before eruption. These data also show that juvenile material was ejected from the first day of the eruption. Phreatomagmatic ejecta overlying the main Anatahan scoria is strongly enriched in 210Po over 210Pb, indicating that a significant proportion of the Po degassed from rising magmas sublimes in its shallow fumarolic conduit system.

  4. 231Pa excesses in arc volcanic rocks: Constraint on melting rates at convergent margins

    NASA Astrophysics Data System (ADS)

    Huang, Fang; Lundstrom, Craig C.

    2007-11-01

    The 231Pa-235U disequilibria provide greater ability to constrain the rate of mantle melting in convergent margin settings than the more often analyzed 238U-230Th-226Ra systems, which are strongly affected by fluid-addition processes from the subducting slab. Here we present new 231Pa-235U data for 12 samples from the Kick'em Jenny (KEJ) submarine volcano in the Southern Lesser Antilles to define the melting rate at a subduction zone with one of the lowest convergence rates. The KEJ samples have the highest average (231Pa)/(235U) yet measured in global arcs, consistent with other studies of the Southern Lesser Antilles lavas. These results reinforce the previously noted negative correlation between average (231Pa)/(235U) and convergence rate in all arc settings globally. We develop a model to explain this negative correlation and to better constrain melting rates at convergent margins. Assuming that the corner flow velocity is coupled to and equal to the subducting slab velocity, the melting rate, directly reflecting the flux of water added, becomes a linear function of subduction rate. This physical model is then coupled to three different melting models previously developed for calculating U-series disequilibria (reactive porous flow, dynamic, and flux melting). All three models reproduce the globally observed negative correlation between subduction rate and 231Pa excess. Although the style of melting cannot be easily discriminated, the good correspondence between models and observation provides an example of how geochemical and geophysical models can be linked to provide a self-consistent model of melt generation in convergent margin settings.

  5. Les torsions sur testicules cryptorchides

    PubMed Central

    Gharbi, Mohamed; Amri, Najmeddine; Chambeh, Wahib; Braiek, Salem; Kamel, Rafik El

    2010-01-01

    Résumé But : La cryptorchidie est une pathologie assez fréquente en urologie. Elle est associée à un risque élevé d’infertilité et de dégénérescence. Elle semble aussi être associée à un risque important de torsion. Cette entité est très peu abordée dans la littérature. Nous rapportons tous les cas de torsion sur testicule cryptorchide observés à notre service dans le but de mieux caractériser cette pathologie et de réduire ainsi le taux d’orchidectomies. Méthodologie : Il s’agit d’une étude rétrospective portant sur tous les cas de torsion sur testicule cryptorchide opérés dans notre service d’urologie entre 1999 et 2007. Les patients ont fait l’objet d’une description basée sur le résumé de leurs observations. Résultats : Les patients étaient âgés de 7 mois à 39 ans. La torsion touchait le testicule droit dans 53 % des cas. Le tableau clinique comportait une douleur au niveau de la région inguinale d’apparition soudaine avec une masse sous-cutanée inflammatoire et douloureuse à ce niveau et surtout un hémiscrotum homolatéral vide. Dans 60 % des cas, le diagnostic était tardif et une orchidectomie a été réalisée. Dans les autre cas, un abaissement du testicule a été réalisé avec orchidopexie controlatéral dans le même temps opératoire. Conclusion : Bien qu’il s’agisse d’une pathologie peu courante, la torsion sur testicule cryptorchide doit être étudiée davantage. Le diagnostic précoce permettra de sauver et d’abaisser le testicule et faciliter ainsi le dépistage d’une éventuelle dégénérescence. PMID:21191497

  6. Scored Discussions.

    ERIC Educational Resources Information Center

    Zola, John

    1992-01-01

    Suggests a classroom strategy to help students learn to analyze and discuss significant issues from history and current policy debates. Describes scored discussions in which small groups of students receive points for participation. Provides an example of a discussion on gold mining. Includes an agenda. Explores uses of scored discussions and…

  7. Traditional medicine of Baja California Sur (Mexico). II.

    PubMed

    Encarnacion Dimayuga, R; Fort Murillo, R; Luis Pantoja, M

    1987-08-01

    Continuing our studies of traditional medicine, as used in rural areas of Baja California Sur, now we wish to report on the medicinal uses of 49 more plants. Some of the more complex recipes of these medicinal plants, are discussed in the present paper. The information presented here was collected in the Municipio of Los Cabos and part of the Municipio of La Paz, B.C.S., Mexico.

  8. A Discussion.

    ERIC Educational Resources Information Center

    Interchange on Education, 1984

    1984-01-01

    A panel discusses the importance of mission-oriented research in a university relative to that of curiosity-based research. Discussants include Wes Cragg, John Leyerle, Gordon Slemon, David Olson, Jack Stevenson, and Bob Czerny. (CJB)

  9. Reframing Discussions

    ERIC Educational Resources Information Center

    Sherry, Michael B.

    2010-01-01

    Recitations and discussions are two types of interactions which have long been of interest to researchers who study classroom discourse in secondary English and Social Studies. According to research, teachers control the discourse during recitations through "inauthentic" questions requiring pre-specified answers. In contrast, discussions involve…

  10. Strengthening Discussions

    ERIC Educational Resources Information Center

    Hintz, Allison B.

    2013-01-01

    "Strategy sharing" is a certain type of discussion that centers on students' ideas and occurs when children present different approaches to problems and provide information about how they solved the problem (Wood, Williams, and McNeal 2004). A teacher may orchestrate a strategy-sharing discussion to achieve one or more of the…

  11. Reframing Discussions

    ERIC Educational Resources Information Center

    Sherry, Michael B.

    2010-01-01

    Recitations and discussions are two types of interactions which have long been of interest to researchers who study classroom discourse in secondary English and Social Studies. According to research, teachers control the discourse during recitations through "inauthentic" questions requiring pre-specified answers. In contrast, discussions involve…

  12. Le Point sur... Astronomie IV

    NASA Astrophysics Data System (ADS)

    Pecker, J.-C.

    Cet ouvrage regroupe des articles de mise au point sollicités par le rédacteur en chef de la rubrique Astronomie des Comptes rendus de l'Académie des sciences. Les textes se proposent de faire découvrir aux lecteurs, dans les principales disciplines de l'astronomie, les résultats les plus remarquables des dernières années.Leurs auteurs sont des spécialistes participant activement à l'accroissement des connaissances dans des domaines faisant l'objet de recherches intensives. Ces mises au point sur des questions particulièrement importantes de l'astronomie sont rédigées soit en français, soit en anglais et accompagnées d'une bibliographie détaillée.

  13. Fires Burning near Big Sur, California

    NASA Image and Video Library

    2008-06-30

    Fires near Big Sur, Calif., continued to burn unchecked when the Advanced Spaceborne Thermal Emission and Reflection Radiometer ASTER instrument on NASA Terra satellite captured this image on Sunday, June 29, 2008.

  14. Case Discussion

    PubMed Central

    Christmas, Colleen; Mears, Simon C.; Sieber, Frederick E.; Votsis, Julie; Wood, Ronald C.; Friedman, Susan M.

    2011-01-01

    This case presents a discussion of a 92-year-old man with multiple comorbidities, who presents with a subtrochanteric fracture. His course is complicated by large volume blood loss intraoperatively, requiring intensive care unit (ICU) monitoring postoperatively. His course is also complicated by delirium. PMID:23569687

  15. Developing Discussion

    ERIC Educational Resources Information Center

    Maloch, Beth; Bomer, Randy

    2012-01-01

    Researchers and educators have long argued for the importance of providing time and space for rich conversations around literature. This column draws on research to consider how teachers make room for these discussions inside their classrooms. Particularly, the authors consider different dimensions along which teachers might examine and grow…

  16. Risky Discussions

    ERIC Educational Resources Information Center

    Cook, Julian; Jacobs, Neil

    2006-01-01

    This article considers a hypothetical decision by a hypothetical learner about whether or not to participate in an online "discussion", viewed through the lens of risk analysis. It begins with the premise that participation online is desirable but that it involves the participant in risk, a fact that needs to be acknowledged and taken into account…

  17. [Discussing abortion].

    PubMed

    1997-01-01

    Discussions with several groups of low-income, middle-aged women in various countries of Latin America showed that most disapproved of abortion. In the course of group discussions about the motives of women who seek abortions and the psychological and sanitary conditions under which abortion occurs, however, their disapproval became less categorical. They began to accept the need to decriminalize abortion in order to protect women. The majority, strongly influenced by the Catholic Church, believed that human life begins at conception. Others disapproved of abortion because they feared it would be used as a birth control method and would encourage promiscuity. Most disapproved of abortion for single women attempting to escape family or social censure of unmarried motherhood. Fear of health effects or death from abortion and fear of divine punishment were also mentioned. Recognition of the anguish and pain suffered by women deciding to seek abortion and the difficulty of providing for the material and other needs of many children were factors that led to reconsideration of the wholesale condemnation of abortion. The women realized that such condemnations never take the woman's circumstances into account. Some of the women felt that aborting an unwanted pregnancy would be preferable to abandoning or neglecting an unwanted child. Many of the women came to feel that abortion should be legalized at least under some circumstances.

  18. Pockmarks off Big Sur, California

    USGS Publications Warehouse

    Paull, C.; Ussler, W.; Maher, N.; Greene, H. Gary; Rehder, G.; Lorenson, T.; Lee, H.

    2002-01-01

    A pockmark field was discovered during EM-300 multi-beam bathymetric surveys on the lower continental slope off the Big Sur coast of California. The field contains ??? 1500 pockmarks which are between 130 and 260 m in diameter, and typically are 8-12 m deep located within a 560 km2 area. To investigate the origin of these features, piston cores were collected from both the interior and the flanks of the pockmarks, and remotely operated vehicle observation (ROV) video and sampling transects were conducted which passed through 19 of the pockmarks. The water column within and above the pockmarks was sampled for methane concentration. Piston cores and ROV collected push cores show that the pockmark field is composed of monotonous fine silts and clays and the cores within the pockmarks are indistinguishable from those outside the pockmarks. No evidence for either sediment winnowing or diagenetic alteration suggestive of fluid venting was obtained. 14C measurements of the organic carbon in the sediments indicate continuous sedimentation throughout the time resolution of the radiocarbon technique ( ??? 45000 yr BP), with a sedimentation rate of ??? 10 cm per 1000 yr both within and between the pockmarks. Concentrations of methane, dissolved inorganic carbon, sulfate, chloride, and ammonium in pore water extracted from within the cores are generally similar in composition to seawater and show little change with depth, suggesting low biogeochemical activity. These pore water chemical gradients indicate that neither significant accumulations of gas are likely to exist in the shallow subsurface ( ??? 100 m) nor is active fluid advection occurring within the sampled sediments. Taken together the data indicate that these pockmarks are more than 45000 yr old, are presently inactive, and contain no indications of earlier fluid or gas venting events. ?? 2002 Elsevier Science B.V. All rights reserved.

  19. AirMSPI PODEX BigSur Terrain Images

    Atmospheric Science Data Center

    2013-12-13

    ... Browse Images from the PODEX 2013 Campaign   Big Sur target (Big Sur, California) 02/03/2013 Terrain-projected   Select ...   Version number   For more information, see the Data Product Specifications (DPS)   ...

  20. ABCC9/SUR2 in the brain: implications for hippocampal sclerosis of aging and a potential therapeutic target

    PubMed Central

    Nelson, Peter T.; Jicha, Gregory A.; Wang, Wang-Xia; Ighodaro, Eseosa; Artiushin, Sergey; Nichols, Colin G.; Fardo, David W.

    2015-01-01

    The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a component of the ATP-sensitive potassium (“KATP”) channel, a metabolic sensor for stress and/or hypoxia that has been shown to change in aging. The KATP channel also helps regulate the neurovascular unit. Most brain cell types express SUR2, including neurons, astrocytes, oligodendrocytes, microglia, vascular smooth muscle, pericytes, and endothelial cells. Thus it is not surprising that ABCC9 gene variants are associated with risk for human brain diseases. For example, Cantu syndrome is a result of ABCC9 mutations; we discuss neurologic manifestations of this genetic syndrome. More common brain disorders linked to ABCC9 gene variants include hippocampal sclerosis of aging (HS-Aging), sleep disorders, and depression. HS-Aging is a prevalent neurological disease with pathologic features of both neurodegenerative (aberrant TDP-43) and cerebrovascular (arteriolosclerosis) disease. As to potential therapeutic intervention, the human pharmacopeia features both SUR2 agonists and antagonists, so ABCC9/SUR2 may provide a “druggable target”, relevant perhaps to both HS-Aging and Alzheimer’s disease. We conclude that more work is required to better understand the roles of ABCC9/SUR2 in the human brain during health and disease conditions. PMID:26226329

  1. ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target.

    PubMed

    Nelson, Peter T; Jicha, Gregory A; Wang, Wang-Xia; Ighodaro, Eseosa; Artiushin, Sergey; Nichols, Colin G; Fardo, David W

    2015-11-01

    The ABCC9 gene and its polypeptide product, SUR2, are increasingly implicated in human neurologic disease, including prevalent diseases of the aged brain. SUR2 proteins are a component of the ATP-sensitive potassium ("KATP") channel, a metabolic sensor for stress and/or hypoxia that has been shown to change in aging. The KATP channel also helps regulate the neurovascular unit. Most brain cell types express SUR2, including neurons, astrocytes, oligodendrocytes, microglia, vascular smooth muscle, pericytes, and endothelial cells. Thus it is not surprising that ABCC9 gene variants are associated with risk for human brain diseases. For example, Cantu syndrome is a result of ABCC9 mutations; we discuss neurologic manifestations of this genetic syndrome. More common brain disorders linked to ABCC9 gene variants include hippocampal sclerosis of aging (HS-Aging), sleep disorders, and depression. HS-Aging is a prevalent neurological disease with pathologic features of both neurodegenerative (aberrant TDP-43) and cerebrovascular (arteriolosclerosis) disease. As to potential therapeutic intervention, the human pharmacopeia features both SUR2 agonists and antagonists, so ABCC9/SUR2 may provide a "druggable target", relevant perhaps to both HS-Aging and Alzheimer's disease. We conclude that more work is required to better understand the roles of ABCC9/SUR2 in the human brain during health and disease conditions. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Constraints on crystal storage timescales in mixed magmas: Uranium-series disequilibria in plagioclase from Holocene magmas at Mount Hood, Oregon

    NASA Astrophysics Data System (ADS)

    Eppich, Gary R.; Cooper, Kari M.; Kent, Adam J. R.; Koleszar, Alison

    2012-02-01

    Uranium-series crystal ages, interpreted within a textural and geochemical framework, can provide insight into crystal storage timescales, especially in cases where crystals may derive from multiple sources. We report here 230Th-226Ra model ages of two distinct populations of plagioclase from low silica dacites from Mount Hood, Oregon, a volcano where previous studies show that the compositions of erupted magmas are controlled by magma recharge, mixing, and incorporation of plagioclase derived from mafic and silicic end-member magmas. We have measured trace element concentrations and 238U-230Th-226Ra disequilibria in four plagioclase size fractions from the Timberline (1500 a) and Old Maid (215 a) eruptive sequences. After correction for groundmass and apatite contamination, average 230Th-226Ra model ages of large (> 500 μm) plagioclase are > 4.5 ka (Timberline) and > 5.5 ka (Old Maid), with ages of cores that are > 10 ka in each case, indicating that plagioclase derived from silicic magmas crystallized thousands of years before eruptions. These model ages are longer than timescales of repose between eruptions, indicating that these crystals resided in the sub-surface over multiple eruptions, likely stored in a silicic crystal mush zone that periodically interacts with mafic recharge magmas, remobilizing a fraction of the large plagioclase crystals during each eruptive event. After correction for large plagioclase contamination, small (< 500 μm) plagioclase, derived from mafic magmas, have high (226Ra)/Ba relative to equilibrium with liquid proxies (groundmass and mafic inclusion), leading to 230Th-226Ra model ages that are <~3 ka for Old Maid and undefined for Timberline separates. However, the preservation of significant 230Th-226Ra disequilibria require that the majority of crystals in the separate are young (<<10 ka). The high (226Ra)/[Ba] could potentially be explained by rapid crystallization immediately prior to and/or during mixing events, consistent with

  3. 231Pa systematics in postglacial volcanic rocks from Iceland

    NASA Astrophysics Data System (ADS)

    Turner, Simon; Kokfelt, Thomas; Hoernle, Kaj; Lundstrom, Craig; Hauff, Folkmar

    2016-07-01

    Several recent studies have highlighted the potential of combined 238U-230Th and 235U-231Pa systematics to constrain upwelling rates and the role of recycled mafic lithologies in mantle plume-derived basalts. Accordingly, we present measurements of the 231Pa concentrations from 26 mafic volcanic rocks from Iceland, including off-axis basalts from the Snaefellsnes Peninsula, to complement previously published 238U-230Th-226Ra data. 231Pa concentrations vary from 27 to 624 fg/g and (231Pa/235U) ratios from 1.12 to 2.11 with the exception of one anomalous sample from the Southeast Rift which has a 231Pa deficit with (231Pa/235U) = 0.86. An important new result is that basalts from the Southeast Rift and the Snaefellsnes Peninsula define a trend at relatively low (231Pa/235U) for a given (230Th/238U) ratio. Many of the remaining samples fall in or around the global field for ocean island basalts but those from the Mid-Iceland Belt and the Southwest Rift/Reykjanes Peninsula extend to higher (231Pa/235U) ratios at a given (230Th/238U), similar to mid-ocean ridge basalts. In principle, these lavas could result from melting of peridotite at lower pressures. However, there is no reason to suspect that the Mid-Iceland Belt and the Southwest Rift lavas reflect shallower melting than elsewhere in Iceland. In our preferred model, these lavas reflect melting of garnet peridotite whereas those from the Southeast Rift and the Snaefellsnes Peninsula contain a significant contribution (up to 20%) of melt from garnet pyroxenite. This is consistent with incompatible trace element and radiogenic isotope evidence for recycled oceanic crust in these lavas. There is increasing agreement that the displacement of ocean island basalts to lower (231Pa/235U) ratios at a given (230Th/238U), compared to mid-ocean ridge basalts, reflects the role of recycled mafic lithologies such as garnet pyroxenite as well as higher average pressures of melting. It now seems likely that this interpretation may

  4. 238U-230Th equilibrium in arc magmas and implications for the time scales of mantle metasomatism

    NASA Astrophysics Data System (ADS)

    Reubi, Olivier; Sims, Kenneth W. W.; Bourdon, Bernard

    2014-04-01

    Large excesses of 238U and 226Ra relative to 230Th characterize many arc magmas and are commonly interpreted to represent recent addition of slab-derived fluid to the mantle wedge beneath the arc. A significant proportion of arc magmas are, however, in 238U-230Th radioactive equilibrium. This is generally thought to result from “buffering” of the young slab fluid U-series signal by a sediment component in secular equilibrium. Here we present new 238U-230Th-226Ra and 235U-231Pa measurements for historic andesites from Volcán de Colima, Mexico. In all lavas (230Th/238U) are in equilibrium, whereas (231Pa/235U) and (226Ra/230Th) are significantly greater than one. These data demonstrate that arc magmas with (230Th/238U) equilibrium can have significant 231Pa and 226Ra excesses, precluding ageing of the magmas in the crust as the cause of 230Th/238U equilibrium. Quantitative modeling of metasomatic and melting processes further indicates that addition of sediment melts to a depleted mantle wedge produces significant 230Th excesses and that 238U excesses induced by recent addition of fluids derived from the altered oceanic crust are not sufficient to compensate these 230Th excesses. U-series activity ratios in Colima magmas are best explained by models in which the metasomatised mantle returns to secular equilibrium before melting, implying a time lag ⩾350 kyr, with subsequent production of 231Pa and 226Ra excesses by in-growth during melting rather than by addition of slab fluids. Investigation of a global compilation of U-series data in arc magma indicates that our model proposed for Colima applies to most arc magmas in or near (230Th-238U) equilibrium. The time lag between mantle metasomatism and melting appears to vary between hundreds years to more than 350 kyr in subduction zones. We posit that the absence of U/Th elemental fractionation during melting of arc sources in (230Th/238U) equilibrium reflects a higher fO2 compared to MORB sources that yield

  5. Melt generation beneath Arctic Ridges: Implications from U decay series disequilibria in the Mohns, Knipovich, and Gakkel Ridges

    NASA Astrophysics Data System (ADS)

    Elkins, L. J.; Sims, K. W. W.; Prytulak, J.; Blichert-Toft, J.; Elliott, T.; Blusztajn, J.; Fretzdorff, S.; Reagan, M.; Haase, K.; Humphris, S.; Schilling, J.-G.

    2014-02-01

    We present new 238U-230Th-226Ra-210Pb, 235U-231Pa, and Nd, Sr, Hf, and Pb isotope data for the slow- to ultraslow-spreading Mohns, Knipovich, and Gakkel Ridges. Combined with previous work, our data from the Arctic Ridges cover the full range of axial depths from the deep northernmost Gakkel Ridge shallowing upwards to the Knipovich, Mohns, and Kolbeinsey Ridges north of Iceland. Age-constrained samples from the Mohns and Knipovich Ridges have (230Th/238U) activity ratios ranging from 1.165 to 1.30 and 1.101 to 1.225, respectively. The high 230Th excesses of Kolbeinsey, Mohns, and Knipovich mid-ocean ridge basalts (MORB) are erupted from ridges producing relatively thin (Mohns, Knipovich) to thick (Kolbeinsey) oceanic crust with evidence for sources ranging from mostly peridotite (Kolbeinsey) to eclogite-rich mantle (Mohns, Knipovich). Age-constrained lavas from 85°E on the Gakkel Ridge, on the other hand, overlie little to no crust and range from small (˜5%) 230Th excesses to small 238U excesses (˜5%). The strong negative correlation between (230Th/238U) values vs. axial ridge depth among Arctic ridge basalts is controlled not only by solidus depth influence on 238U-230Th disequilibria, but also by variations in mantle source lithology and depth to the base of the lithosphere, which is expected to vary at ultra-slow spreading ridges. Small 231Pa excesses (65% excess) in age-constrained basalts support the presence of eclogite in the mantle source for this region. Conversely, the ultraslow-spreading Gakkel Ridge basalts are homogeneous, with Sr, Nd, and Hf radiogenic isotopic signatures indicative of a long time-averaged depleted mantle source. The Gakkel samples have minimum (226Ra/230Th) ratios ranging from 3.07 to 3.65 ± 3%, which lie along and extend the global negative correlation between 226Ra and 230Th excesses observed in MORB. The new 230Th-226Ra data support a model for global MORB production in which deep melts record interaction with shallower

  6. Magma residence time beneath the Piton de la Fournaise Volcano, Reunion Island, from U-series disequilibria [rapid communication

    NASA Astrophysics Data System (ADS)

    Sigmarsson, Olgeir; Condomines, Michel; Bachèlery, Patrick

    2005-05-01

    The U, Th and Ba concentrations, 238U- 230Th- 226Ra- 210Pb and 228Ra - 232Th disequilibria have been measured in a suite of basalts and oceanites erupted during the last two millennia at Piton de la Fournaise (Réunion Island, Indian Ocean). Most of the variation in the concentration of all three incompatible elements is due to crystal fractionation or accumulation (and incorporation of olivine xenocrysts in the oceanites), but contamination by hydrothermally altered rocks or secondary minerals might explain significant variations in Ba/Th. Basalts with Th contents lower than 2.25 ppm have only been produced in eruptions outside the Enclos Fouqué caldera, whereas more evolved basalts are predominantly observed close to the summit craters, inside the Enclos caldera and the rift-zones. The samples have almost uniform Th/U of 3.95, identical Th isotope ratios (( 230Th/ 232Th) = 0.934) and, therefore, approximately 20% excess of 230Th over 238U. All analysed samples are in 228Ra- 232Th radioactive equilibrium, showing the absence of recent (< 30 years) Ra-Th fractionation. Lava flows erupted inside the Enclos caldera and the rift-zones have ( 226Ra/ 230Th) 0 varying from 1.18 to 1.34, whereas the basalts from craters outside the Enclos caldera and the rift-zones, in addition to the oceanites and the 1945 basalt, have higher ( 226Ra/ 230Th) 0 around 1.40. This value is assumed to represent that of the deep magma entering the central plumbing system, beneath the Enclos caldera. The evolution through time of ( 226Ra/ 230Th) 0 is attributed to alternating episodes of near closed-system evolution in one or several, poorly replenished, deep reservoirs, on timescales of the order of 1000 yr, and episodes of increased re-injection and mixing of the deep magma into older magmas of the previous period. Modelling of such a recent re-injection episode, from 1960 to 1998, suggests a short residence time of about 25 yr and a volume of 0.35 km 3 for the shallow reservoir. At the

  7. Sur8 mediates tumorigenesis and metastasis in colorectal cancer

    PubMed Central

    Lee, Young-Mi; Kaduwal, Saluja; Lee, Kug Hwa; Park, Jong-Chan; Jeong, Woo-Jeong; Choi, Kang-Yell

    2016-01-01

    Sur8, a scaffold protein of the Ras pathway, interacts with Ras and Raf and modulates the Ras-extracellular signal-regulated kinase (ERK) pathway. Here we show that Sur8 is overexpressed in established human colorectal cancer (CRC) cell lines and CRC patient tissues. Moreover, Sur8 expression is increased during liver metastasis in CRC patients. Sur8 knockdown decreases ERK and Akt activities in CRC cell lines, regardless of their K-Ras, B-Raf or PI3K mutation status. Overexpression or knockdown of Sur8 increases or decreases, respectively, the proliferation or transformation of CRC cell lines. Sur8 knockdown attenuates the migration and invasion of HCT116 CRC cells. Subcutaneous or orthotopic injection of HCT116 cells harboring a doxycycline (Dox)-mediated Sur8 knockdown system in nude mice resulted in decreased tumorigenic potential and inhibited the liver metastatic potential of HCT116 cells. Taken together, our data support the role of Sur8 as a promoter of tumorigenesis and liver metastasis in CRC through its modulation of the Ras-ERK and PI3K-Akt signaling pathways. PMID:27469030

  8. Let's Discuss: Teaching Students about Discussions

    ERIC Educational Resources Information Center

    Brank, Eve; Wylie, Lindsey

    2013-01-01

    Research consistently demonstrates the benefits of employing classroom discussions; however, there has been less attention given to teaching students about discussions. The current research compared 2 advanced social psychology courses: 1 without (control) and 1 with (experimental) a week devoted to learning about and discussing discussions.…

  9. Regard sur les lazarets en terre canadienne

    PubMed Central

    Milot, Jean

    2008-01-01

    Puisant dans les nombreuses références qu’offrent les publications médicales canadiennes du milieu du XIXe siècle à nos jours, l’auteur fait découvrir l’existence de lazarets en terre canadienne, décrit l’impact de la maladie sur les conditions vie des lépreux qui y étaient confinés et en souligne les contrecoups tant sur le plan physique et psychologique que social. Il présente un bref aperçu de la maladie, ses symptômes, ses signes ainsi que ses complications oculaires et rappelle les premiers moyens thérapeutiques à base d’huile de chaulmoogra introduits dans la colonie de Tracadie vers 1901. Il illustre son propos en évoquant la vie dans les lazarets de l’île de Sheldrake (1844–1848) et de Tracadie (1848–1965) au Nouveau-Brunswick, puis dans ceux des îles D’Arcy (1891–1924) et de Bentinck (1924–1957) en Colombie-Britannique. PMID:19352451

  10. Adolescence et pornographie sur la toile

    PubMed Central

    Haza, Marion

    2012-01-01

    Dans cet article, nous abordons la question de l’accès à la pornographie sur Internet par les adolescents. Nous déclinons plusieurs facettes de ces rencontres: la rencontre «fortuite», quand les adolescents sont confrontés à des images intempestives, des publicités ou spams avec des contenus pornographiques; la rencontre «spectatrice», quand les adolescents cherchent activement des vidéos ou photos mettant en scène la sexualité; et enfin la rencontre «actrice», quand les adolescents se mettent en scène eux-mêmes, seuls ou à plusieurs, de façon pornographique sur le Net. A partir d’exemple, nous réfléchissons aux enjeux de ces rencontres virtuelles précoces de la sexualité adulte par rapport au développement adolescent et à la représentation de leur propre sexualité en construction. PMID:22876261

  11. Lithiase géante sur enterocystoplastie

    PubMed Central

    Elmortaji, Khalid; Elomri, Ghassane; Bennani, Saad; Rabii, Redouane; Aboutaib, Rachid; Meziane, Fethi

    2014-01-01

    La formation des lithiases est une complication fréquente des entérocystoplasties après cystectomie radicale pour tumeur de vessie infiltrante. Le délai d'apparition dépend des facteurs de risque favorisants notamment les infections urinaires. Néanmoins la survenue de lithiase géante sur néovessie reste exceptionnelle, seulement 5 cas ont été rapportés dans la littérature. Nous rapportons dans ce travail, le cas d'une lithiase géante compliquant une entérocystoplastie chez un malade suivi pour tumeur de vessie infiltrante. PMID:25932070

  12. AirMSPI PODEX Big Sur Ellipsoid Images

    Atmospheric Science Data Center

    2013-12-11

    ... Browse Images from the PODEX 2013 Campaign   Big Sur target 02/03/2013 Ellipsoid-projected   Select link to ...   Version number   For more information, see the  Data Product Specifications (DPS) ...

  13. Lignes directrices canadiennes sur la rhinosinusite chronique

    PubMed Central

    Kaplan, Alan

    2013-01-01

    Résumé Objectif Présenter un résumé clinique des lignes directrices canadiennes sur la rhinosinusite chronique (RSC) qui comporte des recommandations pertinentes aux médecins de famille. Qualité des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique dans la littérature médicale et ont rédigé une ébauche de recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en contenu de l’extérieur, ainsi que l’aval des sociétés médicales (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Canadian Society of Otolaryngology—Head and Neck Surgery, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic d’une RSC se fonde sur le type et la durée des symptômes et une constatation objective d’une inflammation de la muqueuse nasale ou des sinus paranasaux. La rhinosinusite chronique est catégorisée en fonction de la présence ou de l’absence de polypes nasaux et cette distinction entraîne des différences dans le traitement. On traite la rhinosinusite chronique avec polypes nasaux au moyen de corticostéroïdes par voie intranasale. Des antibiotiques sont recommandés quand les symptômes indiquent une infection (douleur ou purulence). Pour une RSC sans polypes nasaux, on recommande des corticostéroïdes par voie intranasale et des antibiotiques de deuxième ligne (par ex. combinaisons amoxicilline–acide clavulanique ou fluoroquinolones à activité accrue contre Gram positif). Une irrigation avec une solution saline, des stéroïdes par voie orale et des tests d’allergies pourraient être appropriées. Si le patient ne répond pas au traitement, il faudrait envisager d

  14. Sulfonylurea receptor -1 (SUR1): genetic and metabolic evidences for a role in the susceptibility to type 2 diabetes mellitus.

    PubMed

    Reis, A F; Velho, G

    2002-02-01

    The pancreatic B-cell ATP-sensitive potassium channel (K(ATP)) is composed of two distinct subunits, an inwardly rectifying ion channel forming the pore (Kir6.2), and a regulatory subunit, namely the sulfonylurea receptor-1 (SUR1), which binds this widely used class of insulin-secreting drugs. Mutations in the genes encoding Kir6.2 and SUR1 may result in familial persistent hyperinsulinemic hypoglycaemia of infancy, demonstrating their role in the regulation of insulin secretion. Studies in various populations with different ethnic background provided evidence that various alleles of single nucleotide polymorphisms (SNPs) in the SUR1 gene, and to a less extent in the Kir6.2 gene, confer a significantly increased risk for the development of type 2 diabetes mellitus (T2DM). Allelic variations of these SNPs were shown to modulate insulin secretion and insulin sensitivity in vivo, thus providing a pathophysiological background to explain their contribution to the genetic susceptibility to T2DM. The aim of this review is to summarise and discuss the significant results of recent literature on the implication of K(ATP), and particularly of SUR1, in the genetic and pathopysiological mechanisms of T2DM.

  15. Internet Discussion Groups.

    ERIC Educational Resources Information Center

    Bull, Glen; Bull, Gina; Sigmon, Tim

    1997-01-01

    Discusses newsgroups, listservs, and Web-based discussion groups. Highlights include major categories of international USENET discussion groups; newsgroups versus mailing lists; newsreaders; news servers; newsgroup subscriptions; newsgroups versus Web discussion groups; linking newsgroups, mailing lists, and the Web; and setting up a news host. A…

  16. Fires Burning near Big Sur, California

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Fires near Big Sur, Calif., continued to burn unchecked when the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra satellite captured this image on Sunday, June 29. In Northern California alone, fires have consumed more than 346,000 acres.At least 18,000 people have deployed to attempt to extinguish or control the flames. Air quality as far away as San Francisco has been adversely impacted by the dense clouds of smoke and ash blowing towards the northwest. The satellite image combines a natural color portrayal of the landscape with thermal infrared data showing the active burning areas in red. The dark area in the lower right is a previous forest fire.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 35.4 by 57 kilometers (21.9 by 34.2 miles) Location: 36.1 degrees North latitude, 121.6 degrees West longitude Orientation: North at top Image Data: ASTER bands 3, 2, and 1 Original Data Resolution: 15 meters (49 feet) Dates Acquired: June 29

  17. Fires Burning near Big Sur, California

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Fires near Big Sur, Calif., continued to burn unchecked when the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra satellite captured this image on Sunday, June 29. In Northern California alone, fires have consumed more than 346,000 acres.At least 18,000 people have deployed to attempt to extinguish or control the flames. Air quality as far away as San Francisco has been adversely impacted by the dense clouds of smoke and ash blowing towards the northwest. The satellite image combines a natural color portrayal of the landscape with thermal infrared data showing the active burning areas in red. The dark area in the lower right is a previous forest fire.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 35.4 by 57 kilometers (21.9 by 34.2 miles) Location: 36.1 degrees North latitude, 121.6 degrees West longitude Orientation: North at top Image Data: ASTER bands 3, 2, and 1 Original Data Resolution: 15 meters (49 feet) Dates Acquired: June 29

  18. Effets de la formation sur la violence conjugale

    PubMed Central

    Zaher, Eman; Keogh, Kelly; Ratnapalan, Savithiri

    2014-01-01

    interventions éducatives à multiples facettes prenaient la forme d’ateliers interactifs, d’apprentissage sur le web et de formation expérientielle. Une autre étude utilisait des discussions de groupes témoins et de la formation et a permis de constater une amélioration dans le signalement de la violence conjugale par les médecins. Les 2 autres études ont relevé une meilleure perception par les médecins en pratique de leur confiance en eux à l’aide d’apprentissage par problèmes en ligne. Conclusion Il a été difficile de déterminer quelle stratégie pédagogique était la plus efficace étant donné que les interventions éducatives et les mesures des résultats variaient entre les études choisies. De brèves interventions pour les médecins en formation postdoctorale amélioraient les connaissances mais ne semblaient pas influencer les comportements. La formation en ligne sous forme d’apprentissage par problèmes améliorait les perceptions des médecins en pratique, leurs connaissances et leurs habiletés quant à la prise en charge de la violence conjugale. La formation des médecins combinée à des interventions de soutien de la part du système semblait bénéfique aux victimes de violence conjugale et augmentait le nombre de demandes de consultations auprès des ressources de soutien à leur intention.

  19. PA Discussion Topics

    DTIC Science & Technology

    2011-02-04

    lower priority discussion ADD-TARDEC Network Centric Military Energy Control (NCMEC) Future discussion ADD-TARDEC M&S for Hybrid Electric Vehicles Future...Electronics Based on SiC(Silicon Carbide) TARDEC has a program – Continue discussion ADD-TARDEC Thermal Management System for Hybrid Electric ... Vehicles TARDEC has a program – Continue discussion ADD-TARDEC Electro-Mechanical Transmission TARDEC has interest, skills and personnel, but no program

  20. Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

    NASA Astrophysics Data System (ADS)

    Amrani, Salah

    La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues

  1. Finding the SurPriSe: A Case Study of a Faculty Learning Community

    ERIC Educational Resources Information Center

    Michel, Roberta M.

    2014-01-01

    This article details a faculty learning community (FLC) that started in 2009 on the campus of a Midwestern University and has evolved into an interdisciplinary research, teaching and social community of practice and learning called SurPriSe. SurPriSe is an acronym that reflects the interest area of the FLC; Sur for surveillance, Pri for privacy,…

  2. Highlights of the Discussions.

    ERIC Educational Resources Information Center

    Olson, Christine M.; Gillespie, Ardyth H.

    1981-01-01

    Summarizes the discussions and identified research priorities from a 1980 Workshop on Nutrition Education Research relating to areas of anthropology, communications, psychology, and social psychology. (DS)

  3. Leading Classroom Discussions

    ERIC Educational Resources Information Center

    Gonzalez, Gloriana; DeJarnette, Anna F.

    2013-01-01

    Classroom discourse is a valuable teaching and learning tool. Discussions allow students to improve their communication and reasoning skills in mathematics and help teachers assess students' understanding of mathematical ideas. To get the greatest benefit from discussion, teachers must elicit student thinking, listen carefully to their ideas,…

  4. Framing Evolution Discussion Intellectually

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.; Cook, Kristin; Buck, Gayle A.

    2011-01-01

    This study examines how a first-year biology teacher facilitates a series of whole-class discussions about evolution during the implementation of a problem-based unit. A communicative theoretical perspective is adopted wherein evolution discussions are viewed as social events that the teacher can frame intellectually (i.e., present or organize as…

  5. Framing Evolution Discussion Intellectually

    ERIC Educational Resources Information Center

    Oliveira, Alandeom W.; Cook, Kristin; Buck, Gayle A.

    2011-01-01

    This study examines how a first-year biology teacher facilitates a series of whole-class discussions about evolution during the implementation of a problem-based unit. A communicative theoretical perspective is adopted wherein evolution discussions are viewed as social events that the teacher can frame intellectually (i.e., present or organize as…

  6. The Use of Discussion.

    ERIC Educational Resources Information Center

    Brunner, Edmund deS.; And Others

    Research on the use of discussion in adult education has been largely concerned with comparing it with the use of other instructional techniques and with measuring opinion change. Many studies, such as Kurt Lewin's study of food habits, have compared the effectiveness of group discussion as contrasted with lecture in changing opinions and…

  7. Leading Classroom Discussions

    ERIC Educational Resources Information Center

    Gonzalez, Gloriana; DeJarnette, Anna F.

    2013-01-01

    Classroom discourse is a valuable teaching and learning tool. Discussions allow students to improve their communication and reasoning skills in mathematics and help teachers assess students' understanding of mathematical ideas. To get the greatest benefit from discussion, teachers must elicit student thinking, listen carefully to their ideas,…

  8. The Use of Discussion.

    ERIC Educational Resources Information Center

    Brunner, Edmund deS.; And Others

    Research on the use of discussion in adult education has been largely concerned with comparing it with the use of other instructional techniques and with measuring opinion change. Many studies, such as Kurt Lewin's study of food habits, have compared the effectiveness of group discussion as contrasted with lecture in changing opinions and…

  9. Coastal management at Ojo de Liebre, Baja California Sur

    Treesearch

    Frederico Salinas-Zavala; Alfredo Ortega-Rubio; Diego Valez-Zamudio; Aradit. Castelanos-Vera

    2000-01-01

    We analyzed the biotic, abiotic, and human components interacting at the coastal zone of the Ojo de Liebre Lagoon, Baja California Sur, Mexico. Using geographic information systems, satellite images, and the main biological, physical, and socioeconomic components, we developed an environmental characterization of the zone. According with the natural features of the...

  10. Mining activities and arsenic in a Baja California Sur watershed

    Treesearch

    Alejandro Naranjo-Pulido; Alfredo Ortega-Rubio; Baudillo Acost-Vargas; Lia Rodriguez-Mendez; Marcos Acevedo-Beltran; Cerafina Arguelles-Mendez

    2000-01-01

    Mining is one of the most important sources of income for the Baja California Sur state. This state is the second most important area for mineral (gold, silver, copper) and non-mineral (salt) mining activities in the Mexican Republic. In the San Antonio-El Triunfo region, mineral-mining activities flourished during the 19th century. Tons of debris containing a high...

  11. Demarcating SurA Activities Required for Outer Membrane Targeting of Yersinia pseudotuberculosis Adhesins

    PubMed Central

    Obi, Ikenna R.

    2013-01-01

    SurA is a periplasmic protein folding factor involved in chaperoning and trafficking of outer membrane proteins across the Gram-negative bacterial periplasm. In addition, SurA also possesses peptidyl-prolyl cis/trans isomerase activity. We have previously reported that in enteropathogenic Yersinia pseudotuberculosis, SurA is needed for bacterial virulence and envelope integrity. In this study, we investigated the role of SurA in the assembly of important Yersinia adhesins. Using genetic mutation, biochemical characterization, and an in vitro-based bacterial host cell association assay, we confirmed that surface localization of the invasin adhesin is dependent on SurA. As a surA deletion also has some impact on the levels of individual components of the BAM complex in the Yersinia outer membrane, abolished invasin surface assembly could reflect both a direct loss of SurA-dependent periplasmic targeting and a potentially compromised BAM complex assembly platform in the outer membrane. To various degrees, the assembly of two other adhesins, Ail and the pH 6 antigen fibrillum PsaA, also depends on SurA. Consequently, loss of SurA leads to a dramatic reduction in Yersinia attachment to eukaryotic host cells. Genetic complementation of surA deletion mutants indicated a prominent role for SurA chaperone function in outer membrane protein assembly. Significantly, the N terminus of SurA contributed most of this SurA chaperone function. Despite a dominant chaperoning role, it was also evident that SurA isomerization activity did make a modest contribution to this assembly process. PMID:23589578

  12. Le point sur les amas de galaxies

    NASA Astrophysics Data System (ADS)

    Pierre, M.

    galaxies jouent donc un rôle de premier plan dans toute étude cosmologique et par conséquent, sont indispensables à notre compréhension globale de l'univers. Dans l'introduction générale, nous détaillons cet aspect fondamental en montrant comment l'étude des amas peut contribuer à contraindre les scénarios cosmologiques. Une fois le contexte scientifique délimité, les chapitres suivants s'attachent à présenter les diverses propriétés des amas et leur évolution cosmique observée dans diverses longueurs d'onde principalement dans les domaines visible (galaxies), X (gaz) et radio (gaz et particules). Nous verrons que l'étude détaillée d'un amas implique celle de l'interaction entre ses différentes composantes et est un passage obligé pour remonter au paramètre ultime (ou premier) qu'est sa masse. Loin d'être un détour ennuyeux, ceci sera l'occasion d'aborder des phénomènes physiques extrêmement variés tel l'aspect multi-phases du milieu intra-amas, les sursauts de formation d'étoiles et l'évolution morphologique des galaxies capturées par les amas, ou bien encore, l'interaction entre le plasma intra-amas et les particules relativistes accélérées lors de la fusion entre deux amas. Bien sûr, pour chaque longueur d'onde, nous ne manquerons pas de décrire simplement les techniques d'observation et d'analyse mises en oeuvre ; celles-ci sont particulièrement intéressantes dans le cas de l'instrumentation spatiale. Nous terminerons en présentant des projets d'observatoires pour l'horizon 2010 et leur impact prévu sur l'étude des amas de galaxies.

  13. Facilitating Productive Discussions

    ERIC Educational Resources Information Center

    Cengiz, Nesrin

    2013-01-01

    Whole-group classroom discussions about solutions allow teachers to promote reasoning that moves students beyond merely noticing mathematical ideas toward developing a well-connected knowledge of concepts. Creating classroom environments where teachers promote reasoning and engage students in investigating important mathematical phenomena is…

  14. Promoting Lively Literature Discussion

    ERIC Educational Resources Information Center

    Gritter, Kristine

    2011-01-01

    When students create personal connections with literature during whole-class discussion, they make sense both of text and of their life experiences. In this article, the author shares tips that help students make text-to-self, text-to-world, and text-to-text connections. She offers classroom examples to illustrate how conversations that encourage…

  15. Framing Discussions about Teaching

    ERIC Educational Resources Information Center

    Danielson, Charlotte

    2015-01-01

    Danielson's Framework for Teaching has provided a common language for discussions of teaching practice for almost 20 years. Many educators love the Framework's comprehensiveness; they find the specific language to be useful as they strive to improve their practice. For other educators, however, the Framework's 22 components and 76 smaller elements…

  16. Framing Discussions about Teaching

    ERIC Educational Resources Information Center

    Danielson, Charlotte

    2015-01-01

    Danielson's Framework for Teaching has provided a common language for discussions of teaching practice for almost 20 years. Many educators love the Framework's comprehensiveness; they find the specific language to be useful as they strive to improve their practice. For other educators, however, the Framework's 22 components and 76 smaller elements…

  17. John Cage Discusses Fluxus.

    ERIC Educational Resources Information Center

    Snyder, Ellsworth

    1992-01-01

    Presents an informal discussion with composer John Cage which includes his response to George Maciunas' work, his recollections of Marcel Duchamp, the complex relationship between inelegant material and revealing works of art, neo-Dada and neo-Fluxus, Wittgenstein and the artist's ultimate responsibility to initiate a change in the viewer or…

  18. John Cage Discusses Fluxus.

    ERIC Educational Resources Information Center

    Snyder, Ellsworth

    1992-01-01

    Presents an informal discussion with composer John Cage which includes his response to George Maciunas' work, his recollections of Marcel Duchamp, the complex relationship between inelegant material and revealing works of art, neo-Dada and neo-Fluxus, Wittgenstein and the artist's ultimate responsibility to initiate a change in the viewer or…

  19. Expression and purification of a soluble ESX-binding core domain of SUR2.

    PubMed

    Jeon, Kyung-Hwa; Jun, Kyu-Yeon; Kim, Eun Young; Kwon, Youngjoo

    2013-01-01

    For HER2 overexpression, the ESX transcription factor must interact with both the HER2 promoter and Sur2, a subunit of human mediator complex, using its Ets domain and transactivation domain, respectively. HER2 overexpression is a marker of poor prognosis in various types of cancers. Thus, interfering with the ESX-Sur2 interaction has been suggested as a novel strategy for the treatment of HER2 positive cancers. To design small molecule inhibitors against the ESX-Sur2 interaction, it is necessary to identify the structure of the interface of ESX-Sur2 binding. Therefore, in this study, we determined the optimal conditions for the overexpression and purification of a new version of Sur2, Sur2391-582, which was able to bind to ESX. To stabilize (His)6-Sur2391-582, various different buffered conditions over a wide range of pH and ionic strengths were examined. The molecular mass of (His)6-Sur2391-582 was determined using mass spectroscopy and size exclusion chromatography. The purified (His)6-Sur2391-582 protein displayed the same biological properties as that of the Sur2 full-length protein.

  20. Etude des effets du martelage repetitif sur les contraintes residuelles

    NASA Astrophysics Data System (ADS)

    Hacini, Lyes

    L'assemblage par soudage peut engendrer des contraintes residuelles. Ces contraintes provoquent des fissurations prematurees et un raccourcissement de la duree de vie des composants. Dans ce contexte, le martelage robotise est utilise pour relaxer ces contraintes residuelles. Trois volets sont presentes: le premier est l'evaluation des effets des impacts unitaires repetes sur le champ de contraintes developpe dans des plaques d'acier inoxydable austenitique 304L vierges ou contenant des contraintes residuelles initiales. Dans la deuxieme partie de ce projet, le martelage est applique grace au robot SCOMPI. Les contraintes residuelles induites et relaxees par martelage sont ensuite mesurees par la methode des contours, qui a ete adaptee a cet effet. Dans la troisieme partie, le martelage est modelise par la methode des elements finis. Un modele axisymetrique developpe grace au logiciel ANSYS permet de simuler des impacts repetes d'un marteau elastique sur une plaque ayant un comportement elastoplastique.

  1. COTS Initiative Panel Discussion

    NASA Image and Video Library

    2013-11-13

    Phil McAlister, Director of Commercial Spaceflight Development at NASA, delivers remarks panel discussion on the Commercial Orbital Transportation Services (COTS) initiative at NASA Headquarters in Washington on Wednesday, November 13, 2013. Through COTS, NASA's partners Space Exploration Technologies Corp. (SpaceX) and Orbital Sciences Corp., developed new U.S. rockets and spacecraft, launched from U.S. soil, capable of transporting cargo to low-Earth orbit and the International Space Station. Photo Credit: (NASA/Jay Westcott)

  2. Summaries of group discussions

    NASA Technical Reports Server (NTRS)

    Jensen, L. D.

    1972-01-01

    Group discussions following the presentations of reports on the remote sensing of Chesapeake Bay resources are presented. The parameters to be investigated by the remote sensors and the specifications of the sensors are described. Specific sensors for obtaining data on various aspects of the ecology are identified. Recommendations for establishing a data bank and additional efforts to obtain increased understanding of the ecology are submitted.

  3. COTS Initiative Panel Discussion

    NASA Image and Video Library

    2013-11-13

    Gwynne Shotwell, President of SpaceX, delivers remarks panel discussion on the Commercial Orbital Transportation Services (COTS) initiative at NASA Headquarters in Washington on Wednesday, November 13, 2013. Through COTS, NASA's partners Space Exploration Technologies Corp. (SpaceX) and Orbital Sciences Corp., developed new U.S. rockets and spacecraft, launched from U.S. soil, capable of transporting cargo to low-Earth orbit and the International Space Station. Photo Credit: (NASA/Jay Westcott)

  4. COTS Initiative Panel Discussion

    NASA Image and Video Library

    2013-11-13

    NASA Administrator Charles Bolden delivers remarks before a panel discussion on the Commercial Orbital Transportation Services (COTS) initiative at NASA Headquarters in Washington on Wednesday, November 13, 2013. Through COTS, NASA's partners Space Exploration Technologies Corp. (SpaceX) and Orbital Sciences Corp., developed new U.S. rockets and spacecraft, launched from U.S. soil, capable of transporting cargo to low-Earth orbit and the International Space Station. Photo Credit: (NASA/Jay Westcott)

  5. COTS Initiative Panel Discussion

    NASA Image and Video Library

    2013-11-13

    Frank Slazer, Vice President of Space Systems, Aerospace Industries Association, delivers remarks panel discussion on the Commercial Orbital Transportation Services (COTS) initiative at NASA Headquarters in Washington on Wednesday, November 13, 2013. Through COTS, NASA's partners Space Exploration Technologies Corp. (SpaceX) and Orbital Sciences Corp., developed new U.S. rockets and spacecraft, launched from U.S. soil, capable of transporting cargo to low-Earth orbit and the International Space Station. Photo Credit: (NASA/Jay Westcott)

  6. Clinicians Discuss Diaper Dermatitis.

    PubMed

    Brucker, Mary; McGuire, Stephanie; Merrill, Lisa; Rossing, Francine; Sayaseng, Kammi

    2015-01-01

    Diaper dermatitis in infants is commonly seen by clinicians in both primary care and acute care settings. The condition can cause significant discomfort for infants and distress for their parents and caregivers. Nursing for Women's Health convened a group of nursing clinicians who work in a variety of settings to discuss the issues and challenges related to preventing and treating diaper dermatitis in both healthy term newborns and premature newborns.

  7. DISCUSSION ON MENINGITIS

    PubMed Central

    1929-01-01

    (1) Meningitis: two groups of cases. (2) A method of washing out the subarachnoid space in cases of septic meningitis secondary to infection of the ear. (3) Discussion on the value of maintaining a positive pressure of the cerebrospinal fluid when operating on a septic region communicating with the subarachnoid space. (4) Leaking cerebrospinal fluid from the region of the ear: operative treatment. PMID:19986899

  8. COTS Initiative Panel Discussion

    NASA Image and Video Library

    2013-11-13

    Alan Lindenmoyer, Manager of Commercial Crew and Cargo Program at NASA, delivers remarks panel discussion on the Commercial Orbital Transportation Services (COTS) initiative at NASA Headquarters in Washington on Wednesday, November 13, 2013. Through COTS, NASA's partners Space Exploration Technologies Corp. (SpaceX) and Orbital Sciences Corp., developed new U.S. rockets and spacecraft, launched from U.S. soil, capable of transporting cargo to low-Earth orbit and the International Space Station. Photo Credit: (NASA/Jay Westcott)

  9. Programmes d’apprentissage en petit groupe basé sur la pratique

    PubMed Central

    Zaher, Eman; Ratnapalan, Savithiri

    2012-01-01

    Résumé Objectif Identifier la forme, le contenu et les effets des programmes d’apprentissage en petit groupe basé sur la pratique (APGBP) auxquels participent des MF. Source des données On a fait une recherche dans les bases de données Ovide MEDLINE, EMBASE et ERIC, de leur création jusqu’à la deuxième semaine de novembre 2011, qui a produit 99 articles. Sélection des études On a inclus dans l’analyse les articles qui décrivaient la forme ou le contenu ou évaluaient des programmes d’APGBP auxquels participaient des MF, c’est-à-dire 13 articles. Synthèse Il existe 2 principales formes d’APGBP. La première est un apprentissage autodirigé, qui comporte un examen et des discussions de cas de patients problématiques ou difficiles. Le contenu de tels programmes varie selon les différents styles d’enseignement. La deuxième forme cible des problèmes particuliers tirés de la pratique pour améliorer certaines connaissances et habiletés ou encore mettre en œuvre de nouveaux guides de pratique en utilisant des cas de patients pour stimuler la discussion du sujet choisi. Les 2 formes se ressemblent sur le plan de l’objectif ultime, sont d’égale importance et sont bien acceptées des apprenants et des facilitateurs. Les évaluations des perceptions des apprenants et des résultats de l’apprentissage indiquent que l’APGBP constitue une méthode pratique et efficace de développement professionnel. Conclusion Les données actuelles font valoir que l’APGBP est une méthode prometteuse de développement professionnel continu pour les MF. De tels programmes peuvent être adaptés en fonction des besoins d’apprentissage. De futures études qui insistent sur les changements dans la pratique découlant de l’APGBP renforceront les données probantes à l’appui de cette forme d’apprentissage et motiveront les médecins et les établissements à l’adopter.

  10. Experiential environmental learning: A case study of innovative pedagogy in Baja Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Schneller, Andrew Jon

    This mixed methods case study describes an innovative two-semester middle school environmental learning course that departs from traditional Mexican expository pedagogy through the incorporation of experiential and service learning. This research takes place in a small middle school in Pescadero, Baja California Sur, Mexico. The research approach utilized in the study adds to the handful of studies in this cross-disciplinary field by employing quantitative methodologies to measure course outcomes on student environmental knowledge, perceptions, and actions, while simultaneously qualitatively describing the behavioral, educational, environmental, and social experiences of students. This research employs Dewey's theories of experience---as well as those of more contemporary authenticity theorists---in order to identify the philosophies that advocate incorporating experiential pedagogy within the curriculum. Implications for Mexican educational policy, practical pedagogical applications, and theory are discussed.

  11. Discussion of optoelectronic HMDASS

    NASA Astrophysics Data System (ADS)

    Liu, Yu; Liu, Xu; Yang, Yi; Sun, Longhe; Liu, Hua

    2000-10-01

    The use of opto-electronic Helmet Mounted Display And Sight System (HMDASS) will decrease responding time for fighter in near distance tussle. See-through type Helmet Mounted Display (HMD), instead of the simple graduation board display, will provide more information and so much as integrate the FLTR image. We research some questions of TFTLCD device in optic- electric HMDASS application, such as luminance, information content & format etc. This paper discuss the luminance question in perspective type LCD-HMD and put forward a display method to increase the reaction velocity for a pilot using opto-electronic Helmet Mounted Sight (HMS).

  12. China's satellite communications discussed

    NASA Astrophysics Data System (ADS)

    Ruhou, Z.

    1986-04-01

    In 1972, China began to enter the age of satellite comunications, and it was realized that satellites could play a large role in television transmission in China. The experimental broadcasting of satellite television programs was begun in 1978, and satisfactory results were obtained. The success of the television transmission demonstration has led to important decisions regarding development of a domestic satellite communications system. Before specialized communications satellites are launched, the decision was made to lease an international communications satellite transmitter. The responsibility of the ground stations were discussed.

  13. Empowerment: a conceptual discussion.

    PubMed

    Tengland, Per-Anders

    2008-06-01

    The concept of 'empowerment' is used frequently in a number of professional areas, from psychotherapy to social work. But even if the same term is used, it is not always clear if the concept denotes the same goals or the same practice in these various fields. The purpose of this paper is to clarify the discussion and to find a plausible and useful definition of the concept that is suitable for work in various professions. Several suggestions are discussed in the paper, for example control over life or health, autonomy, ability, self-efficacy, self-esteem, and freedom, and it is concluded that there are two plausible complementary uses, one as a goal and one as a process or approach. Empowerment as a goal is to have control over the determinants of one's quality of life, and empowerment as a process is to create a professional relation where the client or community takes control over the change process, determining both the goals of this process and the means to use.

  14. Effets des electrons secondaires sur l'ADN

    NASA Astrophysics Data System (ADS)

    Boudaiffa, Badia

    Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

  15. Medical Physics Panel Discussion

    NASA Astrophysics Data System (ADS)

    Guèye, Paul; Avery, Steven; Baird, Richard; Soares, Christopher; Amols, Howard; Tripuraneni, Prabhakar; Majewski, Stan; Weisenberger, Drew

    2006-03-01

    The panel discussion will explore opportunities and vistas in medical physics research and practice, medical imaging, teaching medical physics to undergraduates, and medical physics curricula as a recruiting tool for physics departments. Panel members consist of representatives from NSBP (Paul Guèye and Steven Avery), NIH/NIBIB (Richard Baird), NIST (Christopher Soares), AAPM (Howard Amols), ASTRO (Prabhakar Tripuraneni), and Jefferson Lab (Stan Majewski and Drew Weisenberger). Medical Physicists are part of Departments of Radiation Oncology at hospitals and medical centers. The field of medical physics includes radiation therapy physics, medical diagnostic and imaging physics, nuclear medicine physics, and medical radiation safety. It also ranges from basic researcher (at college institutions, industries, and laboratories) to applications in clinical environments.

  16. COTS Initiative Panel Discussion

    NASA Image and Video Library

    2013-11-13

    L-R: Alan Lindenmoyer, Manager of Commercial Crew and Cargo Program, NASA; Gwynne Shotwell, President, SpaceX; Frank Culbertson, Executive Vice President and General Manager, Orbital Sciences Advanced Programs Group; Frank Slazer, Vice President of Space Systems, Aerospace Industries Association and Phil McAlister, Director of Commercial Spaceflight Development at NASA, participate in a panel discussion on the Commercial Orbital Transportation Services (COTS) initiative at NASA Headquarters in Washington on Wednesday, November 13, 2013. Through COTS, NASA's partners Space Exploration Technologies Corp. (SpaceX) and Orbital Sciences Corp., developed new U.S. rockets and spacecraft, launched from U.S. soil, capable of transporting cargo to low-Earth orbit and the International Space Station. Photo Credit: (NASA/Jay Westcott)

  17. Crustal overprint on mantle-derived U-series disequilibria in arc magmas: A warning signal from Volcán Llaima, Chile

    NASA Astrophysics Data System (ADS)

    Reubi, O.; Bourdon, B.; Dungan, M.; Koornneef, J.; Selles, D.; Langmuir, C. H.; Aciego, S.

    2010-12-01

    form Llaima’s subvolcanic basement (the Neogene plutonic roots of the arc). This model reproduces Pa-U-Th disequilibria, Nd isotope, and incompatible trace element ratio arrays. Mixing between the “contaminated” basaltic andesitic magmas with young (several kyr old) intermediate crystal mush additionally affects the trace element contents and 226Ra excesses of the magma erupted during flank eruptions. The Llaima case demonstrates that assimilation of ancestral magmas in the upper crust can produce inclined U-Th isotope arrays and positively correlated (238U/230Th), (226Ra/230Th), and Ba/Th trends which could easily be mistaken as slab-fluid indicators and chronometers, or tracers of sediment recycling in subduction zone. Assimilative recycling of aged plutonic roots of arc volcanoes is likely to be widespread, but is difficult to monitor due to low Nd-Sr-Pb isotopic contrast. Crustal filtering of mantle-derived U-series disequilibria needs to be carefully evaluated.

  18. Assessing Natural Radionuclide Migration in the Legacy Tailings of Uranium Production

    NASA Astrophysics Data System (ADS)

    Bondarenko, G.; Koliabina, I.; Marinich, O.

    2011-12-01

    - 230Th - 226Ra - 210Pb decay chain, typical for closed systems, has been disturbed during selective chemical uranium extraction from the parent ore. We calculated the migration of 210Pb, assuming constant 226Ra activity. The results of these calculations show that over 50 years, ~18% of the initial (unknown) 210Pb(0) activity was removed. If we assume removal of 226Ra decay products will continue at the current level, we expect the future annual activity loss of 210Pb to be about 0.36% per year, or 0.072 Bq/g. Assuming the examined core sample is representative of all 12 million tons of tails, the total annual activity loss is estimated to be ~1012 Bq/year. These results allow us to conclude that the loss of activity from the tailing pit by water migration is mainly associated with the 226Ra decay products: 222Rn, 210Pb, 210Po.
    Activity ratios, Dnieper tailings

  19. Rapid crystal recycling at Krafla Volcano, Iceland, inferred from oxygen-isotope and trace- element compositions and U-Th-Ra disequilibria in plagioclase

    NASA Astrophysics Data System (ADS)

    Cooper, K. M.; Sims, K. W.; Eiler, J. M.; Banerjee, N. R.

    2008-12-01

    The Icelandic central volcano of Krafla exhibits increasing assimilation of hydrothermally-altered crust with increasing differentiation of magmas, as evidenced by decreasing δ18O with decreasing MgO (Nicholson et al., 1991, J Pet 32, p.1005). The Krafla Fires eruption (1975-84) produced two different magma compositions simultaneously: quartz tholeiites near the center of the volcano, and olivine tholeiites north of the central volcano (Gronvold et al., 2008, Goldschmidt abstract). Examination of crystals in these magmas has the potential to provide information about the nature and timescales of mixing of distinct magmas and assimilation of crustal material at Krafla. We present oxygen-isotope compositions, trace-element compositions, and 238U-230Th-226Ra disequilibria measured in plagioclase crystals from samples of lavas erupted during two phases of the Krafla Fires eruption (ol tholeiite erupted Jan-Feb 1981, and qz tholeiite erupted Nov 1981). Oxygen-isotope data for multiple size fractions of plagioclase show a decrease in δ18O with increasing crystal size for the ol tholeiite (from ~4.1 permil to 3.5 permil), whereas there is no clear relationship between plagioclase size and oxygen-isotope composition in the qtz tholeiite (all size fractions average 4.1-4.3 permil). Furthermore, all measured plagioclase have δ18O lower than would be in equilibrium with the whole rock measurements (by up to 1.5 permil). These data imply that (1) few or none of the measured crystals precipitated from the host liquids, and (2) the crystals were entrained in the host magmas shortly prior to eruption, allowing them to maintain oxygen isotopic disequilibrium and heterogeneity within the crystal populations. These inferences are corroborated by trace element compositions measured in plagioclase by laser-ablation ICPMS, as the majority of analyzed points have Ba and Sr concentrations inconsistent with equilibrium partitioning between crystals and liquid. Furthermore, in the case

  20. Cryptic young zircon and young plagioclase in the Kaharoa Rhyolite, Tarawera, New Zealand: Implications for crystal recycling in magmatic systems

    NASA Astrophysics Data System (ADS)

    Klemetti, E. W.; Cooper, K. M.

    2007-12-01

    We measured in-situ 238U-230Th zircon and bulk plagioclase 238U-230Th-226Ra disequilibria in rhyolite lava and tephra from the ~1315 AD Kaharoa eruption of Tarawera Volcano, New Zealand in order to constrain its history of chemical evolution. These data suggest that zircon records a protracted history (10s of kyr) whereas plagioclase is dominantly young (few kyr), but both phases crystallize up to the eruption. The Kaharoa eruptive period at Tarawera consists of ~2.5 km3 of crystal-rich rhyolite (74-75 wt% silica) lava and ~5 km3 of coeval tephra deposits, making it the largest silicic eruption in New Zealand in the last 1,000 years. 238U-230Th disequilibria measurements of zircon determined via SHRIMP-RG analyses produce an array of ages, with three main populations: (1) within error of eruption age; (2) 15-80 k.y.; (3) 100-175 k.y. Very few analyzed zircon fall within error of eruption age and little difference is seen in the age distribution of zircon between the lava and tephra. In contrast, 238U-230Th and 230Th-226Ra plagioclase ages appear to be within error of eruption age however this age is complicated zircon inclusions in the plagioclase. This contamination by zircon is seen in the 238U-230Th disequilibria and trace element data, where the addition of zircon pushes the bulk plagioclase separate towards more U-enriched values and high Zr values. However, the (230Th)/(232Th) ratios for the separates are the same as the whole rock values, indicating that any zircon in the bulk separate must be young (eruption age). This finding is also borne out in 230Th-226Ra disequilibria, where zero-age zircon contamination is reflected in increased (230Th)/[Ba] with no change in (226Ra)/[Ba]. In both cases, as little as 1 ppm of zero-age zircon contamination is needed to create these patterns. This signal of young plagioclase and zircon growth is in contrast to the protracted history seen in the SHRIMP-RG zircon data. This suggests that young zircon growth in the Kaharoa

  1. Constraints on thermal histories of magmas from combined U-series crystal ages, trace-element diffusion, and textural information

    NASA Astrophysics Data System (ADS)

    Cooper, K. M.; Kent, A. J.

    2012-12-01

    Developing a better understanding of the thermal and chemical evolution of magmas within crustal reservoirs has implications both in terms of the mechanisms of generation of chemically diverse magmas and in terms of the development, size and longevity of bodies of eruptible magma. The physical and thermal states of the system are intimately linked, going from mostly liquid to mushy to potentially solid or almost-solid systems as a function largely of temperature. Crystal-scale records show evidence of long-term storage and recycling of crystals within a reservoir system, but the extent to which storage of these antecrysts occurs in mostly-liquid vs. mostly-solid or solid bodies is unclear. Numerical models can provide insights into thermal histories at a reservoir scale, and crystal and liquid thermometry can provide insights into the thermal state of the crystals at snapshots in time, but developing thermal histories from the record in erupted products has been elusive. We present a new approach to quantifying thermal histories of magma bodies using the crystal record by combining information from multiple analytical approaches. U-series crystal ages provide the total time since crystals grew (albeit averaged). In contrast, trace-element zoning provides an uppper limit to the duration of storage at high temperatures, and crystal sizes and CSDs provide insights into the total growth time of crystals (modified by dissolution). Thus, by combining information from all of these sources, we can link the crystal growth and diffusion ages to thermal states and therefore constrain thermal histories. We use recent eruptive products at Mt Hood as a case study, building off of previous 238U-230Th-226Ra crystal age, CSD, and diffusion modeling results. 230Th-226Ra ages of crystals from the silicic endmember of the most recent Mt Hood eruptions both have average ages of >4.5 ka and likely have cores with ages >10 ka (Eppich et al., EPSL, 2012 v. 317-318). Diffusion of Sr in

  2. U-series disequilibria in Kick’em Jenny submarine volcano lavas: A new view of time-scales of magmatism in convergent margins

    NASA Astrophysics Data System (ADS)

    Huang, Fang; Lundstrom, Craig C.; Sigurdsson, Haraldur; Zhang, Zhaofeng

    2011-01-01

    instead propose that most of the 238U- 230Th, 226Ra- 230Th, and 235U- 231Pa disequilibria in erupted KEJ lavas reflect the in-growth melting process in the mantle wedge (reflecting variations in U/Th, daughter-parent ratios, fO 2, and thermal structure), followed by modification by magma differentiation at crustal depths. Such a conclusion reconciles the different temporal implications from different U-series parent-daughter pairs and relaxes the time constraint on mass transfer from slab to eruption occurring in less than a few thousand years imposed by models whereby 226Ra excess is derived from the slab.

  3. Vasodilation induced by oxygen/glucose deprivation is attenuated in cerebral arteries of SUR2 null mice

    PubMed Central

    Adebiyi, Adebowale; McNally, Elizabeth M.

    2011-01-01

    Physiological functions of arterial smooth muscle cell ATP-sensitive K+ (KATP) channels, which are composed of inwardly rectifying K+ channel 6.1 and sulfonylurea receptor (SUR)-2 subunits, during metabolic inhibition are unresolved. In the present study, we used a genetic model to investigate the physiological functions of SUR2-containing KATP channels in mediating vasodilation to hypoxia, oxygen and glucose deprivation (OGD) or metabolic inhibition, and functional recovery following these insults. Data indicate that SUR2B is the only SUR isoform expressed in murine cerebral artery smooth muscle cells. Pressurized SUR2 wild-type (SUR2wt) and SUR2 null (SUR2nl) mouse cerebral arteries developed similar levels of myogenic tone and dilated similarly to hypoxia (<10 mmHg Po2). In contrast, vasodilation induced by pinacidil, a KATP channel opener, was ∼71% smaller in SUR2nl arteries. Human cerebral arteries also expressed SUR2B, developed myogenic tone, and dilated in response to hypoxia and pinacidil. OGD, oligomycin B (a mitochondrial ATP synthase blocker), and CCCP (a mitochondrial uncoupler) all induced vasodilations that were ∼39–61% smaller in SUR2nl than in SUR2wt arteries. The restoration of oxygen and glucose following OGD or removal of oligomycin B and CCCP resulted in partial recovery of tone in both SUR2wt and SUR2nl cerebral arteries. However, SURnl arteries regained ∼60–82% more tone than did SUR2wt arteries. These data indicate that SUR2-containing KATP channels are functional molecular targets for OGD, but not hypoxic, vasodilation in cerebral arteries. In addition, OGD activation of SUR2-containing KATP channels may contribute to postischemic loss of myogenic tone. PMID:21784985

  4. Candida albicans SUR7 contributes to secretion, biofilm formation, and macrophage killing

    PubMed Central

    2010-01-01

    Background Candida albicans SUR7 has been shown to be required for plasma membrane organization and cell wall synthesis, but its role in virulence is not known. Using a bioinformatics strategy, we previously identified several novel putative secretion pathway proteins potentially involved in virulence, including the C. albicans homolog of the Saccharomyces cerevisiae endocytosis-related protein Sur7p. We therefore generated a C. albicans sur7Δ null mutant and examined its contribution to key virulence attributes. Results Structurally, the C. albicans sur7Δ mutant was impaired in response to filamentation-inducing conditions, and formed aberrant hyphae with extensive accumulation of plasma membrane-derived structures within the cell. Absence of SUR7 resulted in a temperature-sensitive growth defect at high temperatures (42°C), which was partially rescued by addition of NaCl. We next examined the role of the SUR7 paralog C. albicans FMP45 in this temperature-sensitive phenotype. Analysis of C. albicans Fmp45p-GFP demonstrated co-localization of Fmp45p with Sur7p and increased fluorescence in the plasma membrane in the presence of high salt. We next focused on key virulence-related phenotypes. The C. albicans sur7Δ null mutant exhibited secretory defects: reduced lipase secretion, and increased levels of secreted Sap2p. The null mutant was hyper-susceptible to sub-inhibitory concentrations of caspofungin, but not amphotericin B and 5-fluorocytosine. Functionally, the sur7Δ mutant demonstrated increased adhesion to polystyrene and of note, was markedly defective in biofilm formation. In an in vitro macrophage model of virulence, the sur7Δ mutant was impaired in macrophage killing. Conclusions Plasma membrane and cell wall organization are important for cell morphology, and alterations of these structures contributed to impairment of several key virulence-associated phenotypes in the C. albicans sur7Δ mutant. PMID:20433738

  5. Requirement of Sur2 for Efficient Replication of Mouse Adenovirus Type 1

    PubMed Central

    Fang, Lei; Stevens, Jennitte L.; Berk, Arnold J.; Spindler, Katherine R.

    2004-01-01

    Mouse adenovirus type 1 (MAV-1) early region 1A (E1A) encodes a virulence gene in viral infection of mice. To broaden our understanding of the functions of E1A in MAV-1 pathogenesis, an unbiased experimental approach, glutathione S-transferase (GST) pulldown, was used to screen for cellular proteins that interact with E1A protein. We identified mouse Sur2, a subunit of Mediator complex, as a protein that binds to MAV-1 E1A. The interaction between Sur2 and MAV-1 E1A was confirmed in virus-infected cells. Conserved region 3 (CR3) of MAV-1 E1A was mapped as the region required for Sur2-E1A interaction, as is the case for human adenovirus E1A. Although it has been proposed that human adenovirus E1A recruits the Mediator complex to transactivate transcription of viral early genes, Sur2 function in adenovirus replication has not been directly tested previously. Studies on the functions of Sur2 with mouse embryonic fibroblasts (MEFs) showed that there was a multiplicity-dependent growth defect of MAV-1 in Sur2−/− MEFs compared to Sur2+/+ MEFs. Comparison of the viral DNA and viral mRNA levels in Sur2+/+ and Sur2−/− MEFs confirmed that Sur2 was important for efficient viral replication. The viral replication defects in Sur2−/− MEFs appeared to be due at least in part to a defect in viral early gene transcription. PMID:15542641

  6. A Recommended Methodology for Quantifying NDE/NDI Based on Aircraft Engine Experience (Le Projet de Methodologie Pour l’Evaluation du Controle Non- Destructif Fonde sur l’Experience Acquise sur les moteurs d’Avions)

    DTIC Science & Technology

    1993-04-01

    A Recommended Methodology for Quantifying NDE/NDI Based on Aircraft Engine Experience--Translation(Le Projet de Methodologie Pour l’Evaluation du Controle Non-Destructif Fonde sur l’Experience Acquise sur les moteurs d’Avions)

  7. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the...

  8. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the...

  9. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the...

  10. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the...

  11. 46 CFR 7.130 - Point Conception, CA to Point Sur, CA.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Point Conception, CA to Point Sur, CA. 7.130 Section 7.130 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.130 Point Conception, CA to Point Sur, CA. (a) A line drawn from the...

  12. The big sur ecoregion sudden oak death adaptive management project: ecological monitoring

    Treesearch

    Allison C. Wickland; Kerri M. Frangioso; David M. Rizzo; Ross K. Meentemeyer

    2008-01-01

    The Big Sur area is one of the most ecologically diverse regions in California. Land preservation efforts are well established in Big Sur, including numerous preserves, state parks and the Los Padres National Forest. However, there are still many conservation threats that cut across these areas including exotic species (plants, animals, and pathogens) and alterations...

  13. Endothelial SUR-8 Acts in an ERK-Independent Pathway During Atrioventricular Cushion Development

    PubMed Central

    Yi, Jing; Chen, Muyun; Wu, Xiaohui; Yang, Xiao; Xu, Tian; Zhuang, Yuan; Han, Min; Xu, Rener

    2010-01-01

    SUR-8, a conserved leucine-rich repeats protein, was first identified as a positive regulator of Ras pathway in Caenorhabditis elegans. Biochemical studies indicated that SUR-8 interacts with Ras and Raf, leading to the elevated ERK activity. However, the physiological role of SUR-8 during mammalian development remains unclear. Here we found that germline deletion of SUR-8 in mice resulted in early embryonic lethality. Inactivated SUR-8 specifically in mouse endothelial cells (ECs) revealed that SUR-8 is essential for embryonic heart development. SUR-8 deficiency in ECs resulted in late embryonic lethality, and the mutant mice displayed multiple cardiac defects. The reduced endothelial-mesenchymal transformation (EMT) and the reduced mesenchyme proliferation phase were observed in the atrioventricular canal (AVC) within the mutant hearts, leading to the formation of hypoplastic endocardial cushions. However, ERK activation did not appear to be affected in mutant ECs, suggesting that SUR-8 may act in an ERK-independent pathway to regulate AVC development. Developmental Dynamics 239:2005–2013, 2010 © 2010 Wiley-Liss, Inc. PMID:20549726

  14. From Bretonneau to therapeutic antibodies, from specificity to specific remedies, Saint-Cyr-Sur-Loire, France, November 19, 2012

    PubMed Central

    Marchand, Claire; Nouat, Romaric; Watier, Hervé

    2013-01-01

    Held on November 19, 2012 in Saint-Cyr-sur-Loire, France, the symposium “From Bretonneau to therapeutic antibodies, from specificity to specific remedies” focused on the historical development of antibodies as therapeutics, with an emphasis on the seminal work of the French physician Pierre-Fidèle Bretonneau (1778–1862). The morning session was devoted to discussion of the evolution of the concept of specificity in medicine, which started with an epistemological definition. The contributions of Bretonneau to the emergence of the concept of specificity, notably with his studies on diphtheria, and the subsequent development of antidiphtheric serotherapy in Europe during the period 1894–1898 were then presented in detail. The afternoon session began with a presentation on the role of French physiologists during the years 1860–1890 in establishing the basic concepts of specific immunity and the principles of serotherapy. The history of antivenom serotherapy, particularly its discovery by Césaire Phisalix, and the development of antilymphocyte globulins as successful transplantation drugs were then discussed. The symposium ended with the inauguration of a stele representing Bretonneau, who lived in Saint-Cyr-sur-Loire and died 150 y ago. PMID:23924799

  15. Lignes directrices simplifiées sur les lipides

    PubMed Central

    Allan, G. Michael; Lindblad, Adrienne J.; Comeau, Ann; Coppola, John; Hudson, Brianne; Mannarino, Marco; McMinis, Cindy; Padwal, Raj; Schelstraete, Christine; Zarnke, Kelly; Garrison, Scott; Cotton, Candra; Korownyk, Christina; McCormack, James; Nickel, Sharon; Kolber, Michael R.

    2015-01-01

    Résumé Objectif Produire un guide de pratique clinique comportant une approche simplifiée à la prévention primaire des maladies cardiovasculaires (MCV), en insistant sur l’estimation du risque de MCV et la prise en charge des profils lipidiques à l’intention des cliniciens de soins primaires et leurs équipes; nous avons recherché la contribution de professionnels des soins primaires qui n’avaient que peu ou pas de conflits d’intérêts et nous nous sommes concentrés sur les données probantes de la plus haute qualité accessibles. Méthodes Neuf professionnels de la santé (4 médecins de famille, 2 internistes, 1 infirmière praticienne, 1 infirmière autorisée et 1 pharmacienne) et 1 membre non votant (pharmacienne gestionnaire de projet) formaient le comité principal appelé le Lipid Pathway Committee (le comité). La sélection des membres s’est fondée sur la profession, le milieu de pratique et son emplacement. Les membres ont divulgué tous leurs conflits d’intérêts potentiels ou réels. Le processus d’élaboration des lignes directrices était itératif et s’appuyait sur des affichages en ligne, une révision détaillée des données probantes, des réunions par téléphone et en ligne. Le comité a cerné 12 questions prioritaires à répondre. Le groupe de révision des données probantes a répondu à ces questions. À la suite d’un examen des réponses, les principales recommandations ont été formulées par consensus du comité. Nous avons produit une ébauche des lignes directrices qui a ensuite été peaufinée, distribuée à un groupe de cliniciens (médecins de famille, autres spécialistes, pharmaciens, infirmières et infirmières praticiennes) et à des patients pour obtenir de la rétroaction, la réviser en conséquence et le comité l’a ensuite finalisée. Recommandations Des recommandations sont présentées concernant le dépistage et les analyses, les évaluations du risque, le suivi, de même que le r

  16. Structure of Thermotoga maritima Stationary Phase Survival Protein SurE: A Novel Acid Phosphatase

    PubMed Central

    Zhang, R.-G.; Skarina, T.; Katz, J.E.; Beasley, S.; Khachatryan, A.; Vyas, S.; Arrowsmith, C.H.; Clarke, S.; Edwards, A.; Joachimiak, A.; Savchenko, A.

    2009-01-01

    Summary Background The rpoS, nlpD, pcm, and surE genes are among many whose expression is induced during the stationary phase of bacterial growth. rpoS codes for the stationary-phase RNA polymerase σ subunit, and nlpD codes for a lipoprotein. The pcm gene product repairs damaged proteins by converting the atypical isoaspartyl residues back to L-aspartyls. The physiological and biochemical functions of surE are unknown, but its importance in stress is supported by the duplication of the surE gene in E. coli subjected to high-temperature growth. The pcm and surE genes are highly conserved in bacteria, archaea, and plants. Results The structure of SurE from Thermotoga maritima was determined at 2.0 Å. The SurE monomer is composed of two domains; a conserved N-terminal domain, a Rossman fold, and a C-terminal oligomerization domain, a new fold. Monomers form a dimer that assembles into a tetramer. Biochemical analysis suggests that SurE is an acid phosphatase, with an optimum pH of 5.5–6.2. The active site was identified in the N-terminal domain through analysis of conserved residues. Structure-based site-directed point mutations abolished phosphatase activity. T. maritima SurE intra- and inter-subunit salt bridges were identified that may explain the SurE thermostability. Conclusions The structure of SurE provided information about the protein’s fold, oligomeric state, and active site. The protein possessed magnesium-dependent acid phosphatase activity, but the physiologically relevant substrate(s) remains to be identified. The importance of three of the assigned active site residues in catalysis was confirmed by site-directed mutagenesis. PMID:11709173

  17. Structure of thermotoga maritima stationary phase survival protein SurE : a novel acid phosphatase.

    SciTech Connect

    Zhang, R.-G; Skarina, T.; Katz, J. E.; Khachatryan, A; Vyas, S.; Arrowsmith, C. H.; Clarke, S.; Edwards, A.; Joachimiak, A.; Savchenko, A.; Biosciences Division; Univ. of Toronto; Univ. of California; Clinical Genomics Centre /Proteomics, Univ. Health Network

    2001-11-01

    Background: The rpoS, nlpD, pcm, and surE genes are among many whose expression is induced during the stationary phase of bacterial growth. rpoS codes for the stationary-phase RNA polymerase {sigma} subunit, and nlpD codes for a lipoprotein. The pcm gene product repairs damaged proteins by converting the atypical isoaspartyl residues back to L-aspartyls. The physiological and biochemical functions of surE are unknown, but its importance in stress is supported by the duplication of the surE gene in E. coli subjected to high-temperature growth. The pcm and surE genes are highly conserved in bacteria, archaea, and plants. Results: The structure of SurE from Thermotoga maritima was determined at 2.0 Angstroms. The SurE monomer is composed of two domains; a conserved N-terminal domain, a Rossman fold, and a C-terminal oligomerization domain, a new fold. Monomers form a dimer that assembles into a tetramer. Biochemical analysis suggests that SurE is an acid phosphatase, with an optimum pH of 5.5-6.2. The active site was identified in the N-terminal domain through analysis of conserved residues. Structure-based site-directed point mutations abolished phosphatase activity. T. maritima SurE intra- and intersubunit salt bridges were identified that may explain the SurE thermostability. Conclusions: The structure of SurE provided information about the protein's fold, oligomeric state, and active site. The protein possessed magnesium-dependent acid phosphatase activity, but the physiologically relevant substrate(s) remains to be identified. The importance of three of the assigned active site residues in catalysis was confirmed by site-directed mutagenesis.

  18. Human Cloning: Let's Discuss It.

    ERIC Educational Resources Information Center

    Taras, Loretta; Stavroulakis, Anthea M.; Ortiz, Mary T.

    1999-01-01

    Describes experiences with holding discussions on cloning at a variety of levels in undergraduate biology courses. Discusses teaching methods used and student reactions to the discussions. Contains 12 references. (WRM)

  19. Human Cloning: Let's Discuss It.

    ERIC Educational Resources Information Center

    Taras, Loretta; Stavroulakis, Anthea M.; Ortiz, Mary T.

    1999-01-01

    Describes experiences with holding discussions on cloning at a variety of levels in undergraduate biology courses. Discusses teaching methods used and student reactions to the discussions. Contains 12 references. (WRM)

  20. Discussion.

    ERIC Educational Resources Information Center

    Davson-Galle, Peter

    2003-01-01

    Explains Philip Higgs' post modern pluralist thought by reaction to the monolithic rigidities of the decreed dogma of his country's (South Africa) past. Author argues that Higgs has overreacted and has become over tolerant of diversity of thought and that intellectual endeavors should be relativised to particular intellectual parochial…

  1. Discussion

    NASA Astrophysics Data System (ADS)

    Crawford, K.

    Presenter, T. P. Grazulis, private consultant [Grazulis et al., this volume, advances in tornado climatology, hazards, and risk assessment since Tornado Symposium II]. (C. Anderson, North Carolina State University.) At one time, I lived in Wisconsin and used to consider tornado climatology there. I noticed some very strange reporting, also. There were a number of counties along the Lake Michigan shore that showed no reported tornadoes from 1915 to 1950. Did you find something like this as well?

  2. Discussion

    NASA Astrophysics Data System (ADS)

    Forbes, Greg

    Presenter, Ted Fujita, University of Chicago [Fujita and Smith, this volume, Aerial survey and photography of tornado and microburst damage]. (Dave Keller, National Severe Storms Laboratory.) All of your damage slides looked like they were taken under sunny and calm conditions. I assume that your surveys were conducted on the day after the tornado. What is the range of weather conditions on the day after the event, and how do the conditions affect your damage surveys?

  3. Discussion

    NASA Astrophysics Data System (ADS)

    Wilkins, Gene

    Presenter, Chris Church, University of Miami, Ohio [Church and Snow, this volume, Laboratory models of tornadoes]. (Brian Fiedler, University of Oklahoma.) When Rich [Rotunno] and I estimated that the maximum vertical velocity would be roughly ten times the average external [vertical] velocity [J. Atmos. Sci., 43, p. 2337, 1986], we did not intend that to be applied to thunderstorms because of the different outflow conditions; that really only applies to the Purdue simulator. We think that ratio is too high in the simulator. In my paper [A4], that ratio was 2, not 10. Could you comment on your new simulator, where there is divergence aloft instead of the fan sucking the air out vertically? What is the ratio of maximum vertical velocity to mean updraft velocity in that simulator? Is it the same as in the Purdue chamber?

  4. Discussion

    NASA Astrophysics Data System (ADS)

    Marshall, Tim

    Presenter, Jim McDonald, Texas Tech University [McDonald, this volume, Damage mitigation and occupant safety]. (Arnold Court, California State University.) Can you tell me how to park my car to mitigate tornado damage?

  5. Discussion

    NASA Astrophysics Data System (ADS)

    McCarthy, D.

    Presenter, C. A. Doswell III, National Severe Storms Laboratory [Doswell, this volume, Tornado forecasting: A review]. (H. Volkman, private consultant.) Who's leading the effort to get SELS [Severe Local Storms; see session H, paper H6] out of the tornado and severe thunderstorm watches? We need to know in case there's some influence we can have to divert this change?

  6. Discussion

    Treesearch

    1991-01-01

    What follows represents the minutes of the workshop on wood-destroying organisms held in Bend, Oregon, September 14, 1989. The theme of the workshop was the state-of-the art of control of wood destroying organisms and the needs for further research on wood-destroying organisms. The agenda for the session was organized by W. Wayne Wilcox and Michael I. Haverty.

  7. Introduction to Small Group Discussion.

    ERIC Educational Resources Information Center

    Millar, Dan Pyle

    To bring educational research into focus with tested classroom practice, this booklet provides an introduction to small group discussion. The theory and research section discusses the importance of small group discussion, characteristics of small group discussions, group attraction based on Maslow's hierarchy of basic human needs, group decision…

  8. SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury

    PubMed Central

    Nicholson, James D.; Guo, Yan; Bernstein, Steven L.

    2016-01-01

    Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models. Despite its importance in CNS injuries, SUR1 upregulation appears to play no part in rodent anterior ischemic optic neuropathy (rAION) injury as tested by real-time PCR and immunohistochemical staining of rAION-injured rat optic nerve (ON). Furthermore, the SUR1 antagonist glibenclamide administered immediately after rAION injury provided no protection to proximal ON microvasculature 1 day post-injury but may reduce optic nerve head edema in a manner unrelated to ON SUR1 expression. Our results suggest that there may be fundamental differences between rAION optic nerve ischemia and other CNS white matter injuries where SUR1 appears to play a role. PMID:27560494

  9. ``Astrophysique sur Mesure'', E-learning in Astronomy and Astrophysics

    NASA Astrophysics Data System (ADS)

    Mosser, Benoît; Delsanti, Audrey; Guillaume, Damien; Balança, Christian; Balkowski, Chantal

    2011-06-01

    ``Astrophysique sur Mesure'' (astrophysics made-to-measure) is a set of e-learning programmes started 4 years ago at the Paris Observatory. In order to deliver attractive and efficient programmes, we have added many multimedia tools to usual lectures: animations, Java applets. The programmes are presented on two different platforms. The first one offers the content of all the lectures in free access. A second platform with restricted access is provided to registered students taking part in the e-learning program and benefiting from the help of tutors. The development of these programs helps to increase the sphere of influence of astronomy taught at the Paris Observatory, hence to increase the presence of astronomy in various degree courses. Instead of teaching classical astronomy lectures to a happy few, we can bring astronomy and astrophysics to a wider audience.

  10. [Marine algae of Baja California Sur, Mexico: nutritional value].

    PubMed

    Carrillo Domínguez, Silvia; Casas Valdez, Margarita; Ramos Ramos, Felipe; Pérez-Gil, Fernando; Sánchez Rodríguez, Ignacio

    2002-12-01

    The Baja California Peninsula is one of the richest regions of seaweed resources in México. The objective of this study was to determine the chemical composition of some marine algae species of Baja California Sur, with an economical potential due to their abundance and distribution, and to promote their use as food for human consumption and animal feeding. The algae studied were Green (Ulva spp., Enteromorpha intestinalis, Caulerpa sertularoides, Bryopsis hypnoides), Red (Laurencia johnstonii, Spyridia filamentosa, Hypnea valentiae) and Brown (Sargassum herporizum, S. sinicola, Padina durvillaei, Hydroclathrus clathrathus, Colpomenia sinuosa). The algae were dried and ground before analysis. In general, the results showed that algae had a protein level less than 11%, except L. johnstonii with 18% and low energy content. The ether extract content was lower than 1%. However, the algae were a good source of carbohydrates and inorganic matter.

  11. A Discussion with Jacques Derrida.

    ERIC Educational Resources Information Center

    Derrida, Jacques

    1990-01-01

    Presents an edited transcript of a discussion held in April 1989 between Jacques Derrida and a group of students and professors concerning Derrida's "Afterword: Toward an Ethic of Discussion." Discusses Derrida's views on "deconstruction" as a term and a movement, the idea of arguments and persuasion, and specific power…

  12. Refuting Misconceptions about Classroom Discussion

    ERIC Educational Resources Information Center

    Wilen, William W.

    2004-01-01

    Social studies educators advocate discussion as an influential instructional method to encourage students to apply knowledge and develop higher-order thinking and understanding. The classroom reality, however, is that teachers only use the discussion method sparingly. Instead, teachers predominantly use a quasi-discussion form called recitation to…

  13. Taos Smart Growth Implementation Assistance: Concepts for the Paseo del Pueblo Sur Corridor

    EPA Pesticide Factsheets

    This report describes a technical assistance project with Taos, NM, to help make development along State Highway 68, the Paseo del Pueblo Sur commercial corridor, economically stronger and more attractive.

  14. Enquete sur les aspects toxicologiques de la phytotherapie utilisee par un herboriste à Fes, Maroc

    PubMed Central

    Zeggwagh, Ali Amine; Lahlou, Younes; Bousliman, Yassir

    2013-01-01

    Introduction Dans le but d'étudier l'aspect toxicologique des plantes médicinales utilisées en médecine traditionnelle, une étude ethnobotanique a été réalisée à la ville de Fès au centre du Maroc. Méthodes Ont été inclus dans l'étude tous les patients ayant bénéficié d'une prescription par l'herboriste de plantes à visée thérapeutique. La discussion de nos résultats s'est faite sur la base d'une revue de la littérature avec identification des principales plantes toxiques utilisées en phytothérapie au Maroc. L'approche bibliographique a permis de compléter les informations. Résultats L'âge moyen des patients traités par des plantes (38 femmes, 32 hommes) était de 35 ± 18 ans. L'enquête ethnobotanique à révélé que la majorité des plantes médicinales étaient utilisées contre les affections urinaires (21%), suivi des maladies de l'appareil digestif (19.6%) et des maladies rhumatologiques (18.2%). Le nombre de plantes prescrits par l'herboriste a été de 53 dont 5 sont potentiellement toxiques. L'identification taxonomique des plantes prescrites a recensé 30 familles dont les plus représentées sont les Lamiaceae (23.33%), les Apiaceae (13,33%) et les Asteraceae (10%). La prescription des plantes considérées comme toxiques a concerné 7,1% des consultants traités par les plantes médicinales. Aucune complication inhérente aux plantes prescrites n'a été déplorée. Conclusion Malgré les résultats encourageants de notre enquête sur le compte de la phytothérapie, la pratique de la phytothérapie est laissée à la vulgarisation et à l'oubli scientifique, législatif et universitaire. PMID:23734270

  15. Modelisations des effets de surface sur les jets horizontaux subsoniques d'hydrogene et de methane

    NASA Astrophysics Data System (ADS)

    Gomez, Luis Fernando

    Le developpement des codes et de normes bases sur une methodologie scientifique requiert la capacite de predire l'etendue inflammable de deversements gazeux d'hydrogene sous differentes conditions. Des etudes anterieures ont deja etabli des modeles bases sur les lois de conservation de la mecanique des fluides basees sur des correlations experimentales qui permettent de predire la decroissance de la concentration et de la vitesse d'un gaz le long de l'axe d'un jet libre vertical. Cette etude s'interesse aux effets de proximite a une surface horizontale parallele sur un jet turbulent. Nous nous interessons a son impact sur l'etendue du champ de la concentration et sur l'enveloppe inflammable en particulier. Cette etude est comparative : l'hydrogene est compare au methane. Ceci permet de degager l'influence des effets de difference de la densite sur le comportement du jet, et de comparer le comportement de l'hydrogene aux correlations experimentales, qui ont ete essentiellement etablies pour le methane. Un modele decrivant l'evolution spatio-temporelle du champ de concentration du gaz dilue est propose, base sur la mecanique des fluides computationnelle. Cette approche permet de varier systematiquement les conditions aux frontieres (proximite du jet a la surface, par exemple) et de connaitre en detail les proprietes de l'ecoulement. Le modele est implemente dans le code de simulations par volumes finis de FLUENT. Les resultats des simulations sont compares avec les lois de similitudes decoulant de la theorie des jets d'ecoulements turbulents libres ainsi qu'avec les resultats experimentaux disponibles. L'effet de la difference des masses molaires des constituantes du jet et des constituantes du milieu de dispersion est egalement etudie dans le contexte du comportement d'echelle de la region developpee du jet.

  16. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to...

  17. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to...

  18. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to...

  19. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to...

  20. 46 CFR 7.135 - Point Sur, CA to Cape Blanco, OR.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Point Sur, CA to Cape Blanco, OR. 7.135 Section 7.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Pacific Coast § 7.135 Point Sur, CA to Cape Blanco, OR. (a) A line drawn from Monterey Harbor Light “6” to...

  1. Ubiquitous Discussion Forum: Introducing Mobile Phones and Voice Discussion into a Web Discussion Forum

    ERIC Educational Resources Information Center

    Wei, Fu-Hsiang; Chen, Gwo-Dong; Wang, Chin-Yeh; Li, Liang-Yi

    2007-01-01

    Web-based discussion forums enable users to share knowledge in straightforward and popular platforms. However, discussion forums have several problems, such as the lack of immediate delivery and response, the heavily text-based medium, inability to hear expressions of voice and the heuristically created discussion topics which can impede the…

  2. Chemical Kinetics Laboratory Discussion Worksheet.

    PubMed

    Demoin, Dustin Wayne; Jurisson, Silvia S

    2013-09-10

    A laboratory discussion worksheet and its answer key provide instructors and students a discussion model to further the students' understanding of chemical kinetics. This discussion worksheet includes a section for students to augment their previous knowledge about chemical kinetics measurements, an initial check on students' understanding of basic concepts, a group participation model where students work on solving complex-conceptual problems, and a conclusion to help students connect this discussion to their laboratory or lecture class. Additionally, the worksheet has a detailed solution to a more advanced problem to help students understand how the concepts they have put together relate to problems they will encounter during later formal assessments.

  3. Chemical Kinetics Laboratory Discussion Worksheet

    PubMed Central

    Demoin, Dustin Wayne; Jurisson, Silvia S.

    2013-01-01

    A laboratory discussion worksheet and its answer key provide instructors and students a discussion model to further the students’ understanding of chemical kinetics. This discussion worksheet includes a section for students to augment their previous knowledge about chemical kinetics measurements, an initial check on students’ understanding of basic concepts, a group participation model where students work on solving complex-conceptual problems, and a conclusion to help students connect this discussion to their laboratory or lecture class. Additionally, the worksheet has a detailed solution to a more advanced problem to help students understand how the concepts they have put together relate to problems they will encounter during later formal assessments. PMID:24092948

  4. A functional role of the C-terminal 42 amino acids of SUR2A and SUR2B in the physiology and pharmacology of cardiovascular ATP-sensitive K(+) channels.

    PubMed

    Yamada, Mitsuhiko; Kurachi, Yoshihisa

    2005-07-01

    The ATP-sensitive K(+) (K(ATP)) channel is composed of four pore-forming Kir6.2 subunits and four sulfonylurea receptors (SUR). Intracellular ATP inhibits K(ATP) channels through Kir6.2. SUR is an ABC protein bearing transmembrane domains and two nucleotide-binding domains (NBD1 and NBD2). SUR increases the open probability of K(ATP) channels by interacting with ATP and ADP through NBDs and with K(+) channel openers such as nicorandil through its transmembrane domain. Because NBDs and the drug receptor allosterically interact with each other, nucleotides and drugs probably activate K(ATP) channels by causing the same conformational change of SUR. SUR2A and SUR2B have the identical drug receptor and NBDs and differ only in the C-terminal 42 amino acids (C42). Nonetheless, nicorandil ~100 times more potently activates SUR2B/Kir6.2 than SUR2A/Kir6.2 channels. Based on our allosteric model, we have analyzed the interaction between NBDs and the drug receptor in SUR2A and SUR2B and found that both nucleotide-bound NBD1 and NBD2 more strongly induce the conformational change in SUR2B than SUR2A. Therefore, C42 modulates the function of not only NBD2 which is close to C42 in a primary structure but NBD1 which is more than 630 amino acid N-terminal to C42. This raises the possibility that in the presence of nucleotides, NBD1 and NBD2 dimerize to induce the conformational change and that the dimerization enables C42 to gain access to both NBDs. Modulation of the nucleotide-NBD1 and -NBD2 interactions by C42 would determine the stability of the nucleotide-dependent dimer and thus, the physiological and pharmacological properties of K(ATP) channels.

  5. Sur Lago area, Venezuela: Three dimensional integrated seismic interpretation

    SciTech Connect

    Growcott, A.; McIan, A.; Ramirez, R. )

    1993-02-01

    In 1988, 550 square km of 3D seismic data were acquired in the Sur Del Lago area. The aims of the survey were (1) To better define structures already identified from the existing 1 [times] 1 km 2D seismic grid at the level of potential Cretaceous limestone reservoirs and (2) To further study the prospectivity of potential structural and stratigraphic traps within the Tertiary section. Detailed interpretation of the 3D survey using an interactive workstation led to an improved structural definition at the Cogollo limestone level and the identification of fault related inversion lineaments and basement related Cretaceous limestone structures. Based upon the new seismic interpretation a 4 well exploration project was planned. The new program commenced with the drilling of exploration well SLA-7-IX in 1991 which proved commercial amounts of hydrocarbons in the western part of the area. Detailed information collected from the exploration wells includes a comprehensive electric log suite, ditch cuttings and vertical seismic profiles. The information is being used as detailed lithological, stratigraphic and seismic data input for velocity modeling, ray trace modeling, seismic attribute analysis, and reservoir characterization software in order to further understand the structural and stratigraphic potential of the area.

  6. Promoting Discussions in ESL Students

    ERIC Educational Resources Information Center

    Navarro, Ann

    2010-01-01

    Background: Teachers who work with English as a Second Language (ESL) students, struggle with promoting discussion during guided reading. When ESL students are asked comprehension questions during group discussions and throughout the reading of a book, often teachers receive minimal feedback. Purpose: The purpose of this research is to identify…

  7. Emotional discussions reduce memory recall.

    PubMed

    Soleti, Emanuela; Wright, Daniel B; Curci, Antonietta

    2017-05-01

    People often discuss events they have seen and these discussions can influence later recollections. We investigated the effects of factual, emotional, and free retelling discussion on memory recollections of individuals who have witnessed an event. Participants were shown a video, made an initial individual recall, participated in one of the three retelling conditions (emotional versus factual versus free) or a control condition, and then recalled the event individually again. Participants in the factual and free retelling conditions reported more items not previously recalled than participants in the control condition did, while the emotional condition did not show the same advantage. Participants in all three retelling conditions failed to report more previously recalled items as compared with the control condition. Finally, a memory conformity effect was observed for all three retelling conditions. These findings suggest that eyewitnesses' discussions may influence the accuracy of subsequent memory reports, especially when these discussions are focused on emotional details and thoughts.

  8. Small group discussion: Students perspectives.

    PubMed

    Annamalai, Nachal; Manivel, Rajajeyakumar; Palanisamy, Rajendran

    2015-08-01

    Various alternative methods are being used in many medical colleges to reinforce didactic lectures in physiology. Small group teaching can take on a variety of different tasks such as problem-solving, role play, discussions, brainstorming, and debate. Research has demonstrated that group discussion promotes greater synthesis and retention of materials. The aims of this study were to adopt a problem-solving approach by relating basic sciences with the clinical scenario through self-learning. To develop soft skills, to understand principles of group dynamics, and adopt a new teaching learning methodology. Experimental study design was conducted in Phase I 1(st) year medical students of 2014-2015 batch (n = 120). On the day of the session, the students were grouped into small groups (15 each). The session started with the facilitator starting off the discussion. Feedback forms from five students in each group was taken (n = 40). A five point Likert scale was used ranging from strongly agree to strongly disagree. Data were analyzed using IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp. Our results show that 70% of the students opined that small group discussion were interactive, friendly, innovative, built interaction between teacher and student. Small group discussion increased their thought process and helped them in better communication. The small group discussion was interactive, friendly, and bridged the gap between the teacher and student. The student's communication skills are also improved. In conclusion, small group discussion is more effective than the traditional teaching methods.

  9. Socrates, discussion and moral education

    NASA Astrophysics Data System (ADS)

    Rembert, Ron B.

    1995-01-01

    For Socrates, as he appears in Plato's dialogues, the process of discussion is essential for preparing human beings to lead a moral life. Only through discussion, Socrates maintains, can we be led to an understanding of such concepts as wisdom, courage and justice. The author of this article believes that the Socratic notion of the moral value of discussion is still valid. In support of this view, he examines two recent works: Dialogues on Moral Education by John Wilson and Barbara Cowell, and Moral Education, Secular and Religious by John L. Elias. Finally, the author suggests how the Socratic concept of dialogue might be used in moral education today.

  10. Cochlear amplification: A moderated discussion

    NASA Astrophysics Data System (ADS)

    Elliott, Stephen; Grosh, Karl; Puria, Sunil

    2015-12-01

    The following is an edited transcript of a recorded discussion session on the topic of "Cochlear Amplification". The discussion, moderated by the authors, took place at the 12th International Workshop on the Mechanics of Hearing held at Cape Sounio, Greece, in June 2014. All participants knew that the session was being recorded. In view of both the spontaneous nature of the discussion and the editing, however, this transcript may not represent the considered or final views of the participants, and may not represent a consensus of experts in the field. The reader is advised to consult additional independent publications.

  11. Three-phase Discussion Sessions.

    ERIC Educational Resources Information Center

    Karr, M. C.; And Others

    1988-01-01

    Describes the procedures, organizational pattern and design of basic soils course used by teaching assistants. Cites studies which support small-group discussion for promoting higher levels of intellectual functioning. Presents tables showing survey evaluation results of this method. (RT)

  12. Space Launch System Panel Discussion

    NASA Image and Video Library

    2013-11-12

    Models of the Space Launch System and Orion spacecraft are displayed during a panel discussion on deep space eploration at the Newseum on Tuesday, November 12, 2013 in Washington. Photo Credit: (NASA/Jay Westcott)

  13. Animating Geometry Discussions with Flexigons.

    ERIC Educational Resources Information Center

    McClintock, Ruth

    1994-01-01

    Presents activities with 10- and 4-straw flexigons, an object created by stringing together lengths of plastic drinking straws with nylon fishing line. Discusses several geometric theorems that can be demonstrated with flexigons. (MKR)

  14. Animating Geometry Discussions with Flexigons.

    ERIC Educational Resources Information Center

    McClintock, Ruth

    1994-01-01

    Presents activities with 10- and 4-straw flexigons, an object created by stringing together lengths of plastic drinking straws with nylon fishing line. Discusses several geometric theorems that can be demonstrated with flexigons. (MKR)

  15. Discussion of "interpretation and play".

    PubMed

    Pick, Irma Brenman

    2011-01-01

    This discussion addresses the conflict in technique between play versus interpretation. It further considers how the nature of the interpretation may be affected by a consideration of what is being projected into the analyst.

  16. Synchronous computer mediated group discussion.

    PubMed

    Gallagher, Peter

    2005-01-01

    Over the past 20 years, focus groups have become increasingly popular with nursing researchers as a data collection method, as has the use of computer-based technologies to support all forms of nursing research. This article describes the conduct of a series of focus groups in which the participants were in the same room as part of a "real-time" discussion during which they also used personal computers as an interface between each other and the moderator. Synchronous Computer Mediated Group Discussion differed from other forms of focus group discussion in that participants used personal computers rather than verbal expressions to respond to specific questions, engage in communication with other participants, and to record their thoughts. This form of focus group maintained many of the features of spoken exchanges, a cornerstone of the focus group, while capturing the advantages of online discussion.

  17. Discussion: Confronting theory and experiment

    SciTech Connect

    Gallagher, Hugh; Hayato, Yoshinari; Sobczyk, Jan

    2015-05-15

    This session focused on the current status of neutrino event generators, in practical terms the tool through which ‘theory confronts experiment’. Comparisons of event generators, both in terms of input physics, and in terms of produced distributions, has been a staple of this conference series, and the activities in this area are summarized. In addition, we discuss the highest priorities for model development, discuss the changing needs of experimental users, and comment on challenges and needs for the road ahead.

  18. LGBT Roundtable Discussion: Meet-up and Mentoring Discussion

    NASA Astrophysics Data System (ADS)

    2014-03-01

    The LGBT+ Physicists group welcomes those who identify as gender sexual minorities, as LGBTQQIAAP+, or as allies to participate in a round-table discussion on mentoring physicists. The session will provide an opportunity to learn and discuss successful mentoring strategies at different career stages for physicists in all environments, including academia, industry, etc. Attendees are encouraged to attend a social event to follow the panel to continue to network. Allies are especially welcome at this event to learn how to support and mentor LGBT+ physicists.

  19. Conséquences des nouvelles formes de commande sur les matériaux de l'isolation statorique

    NASA Astrophysics Data System (ADS)

    Bellomo, J. P.; Lebey, Th.; Peltier, Fr.; Oraison, J. M.

    1997-05-01

    Use of inverter drive for rotating machines speed control leads to the application of new stress on stator insulation materials. The integrity of these materials under such stresses has therefore to be studied. Thanks to specially equipped motor, the different voltage shapes have been identified. Very short rise time fronts, large overvoltages and high oscillation frequencies are obtained. These voltages are then reproduced on laboratory samples (Polyethylene Terephtalate). The main result is the existence of trapped surface charges related both to the rise front value and to the existence of polar mechanisms in the material bulk. The consequences of this surface charge existence on the reliability of a real system are then discussed. L'utilisation de nouvelles formes de commande pour les machines à courant alternatif se traduit par l'apparition d'un nouveau type de contraintes sur les matériaux de l'isolation statorique. L'étude de leur comportement sous l'action de ce type de contraintes revêt un intérêt tout particulier pour la validation et la stabilité de ces systèmes dans le temps. Nous présentons, tout d'abord, ces différentes formes de tension identifiées à l'aide d'un moteur spécialement instrumenté. L'existence de fronts de tension très élevés, de surtensions importantes (jusqu'à 500V) et d'oscillations hautes fréquences (2MHz), est mise en évidence. La reproduction de ces contraintes en laboratoire sur des échantillons de polyesters (PolyÉthylène Térephthalate) permet alors de déterminer l'influence des formes de tension carrées sur les propriétés intrinsèques du matériau. Elle se traduit par l'existence d'une charge piégée en surface du diélectrique. Cette charge superficielle est associée, d'une part à l'existence de phénomènes de relaxation dans les matériaux étudiés et d'autre part à la valeur des fronts de tension appliqués. Pour finir, les conséquences possibles de l'existence de ces charges superficielles

  20. Speed-Discussion: Engaging Students in Class Discussions

    ERIC Educational Resources Information Center

    Kornfield, Sarah; Noack, Kristen

    2017-01-01

    Courses: Communication Criticism, Rhetorical Criticism, Family and Communication, Gender and Communication, Popular Communication, and theory-based courses. Objectives: This activity engages students in dynamic, supportive, social discussion groups; helps them to identify and review the central ideas from the reading; and creates a record of their…

  1. Sur domains that associate with and gate KATP pores define a novel gatekeeper.

    PubMed

    Babenko, Andrey P; Bryan, Joseph

    2003-10-24

    Structure-function analyses of K+ channels identify a common pore architecture whose gating depends on diverse signal sensing elements. The "gatekeepers" of the long, ATP-inhibited KIR6.0 pores of KATP channels are ABC proteins, SURs, receptors for channel opening and closing drugs. Several competing models for SUR/KIR coupling exist. We show that SUR TMD0, the N-terminal bundle of five transmembrane helices, specifically associates with KIR6.2, forcing nearly silent pores to burst like native KATP channels and enhancing surface expression. Inclusion of adjacent submembrane residues of L0, the linker between TMD0 and the stimulatory nucleotide- and drug-binding ABC core, generates constitutively active channels, whereas additional cytoplasmic residues counterbalance this activation establishing a relationship between the mean open and burst times of intact pores. SUR fragments, lacking TMD0, fail to modulate KIR. TMD0 is thus the domain that anchors SUR to the KIR pore. Consistent with data on chimeric ABCC/KIRs and a modeled channel structure, we propose that interactions of TMD0-L0 with the outer helix and N terminus of KIR bidirectionally modulate gating. The results explain and predict pathologies associated with alteration of the 5' ends of clustered ABCC8 (9)/KCNJ11 (8) genes.

  2. ATP-sensitive potassium currents from channels formed by Kir6 and a modified cardiac mitochondrial SUR2 variant

    PubMed Central

    Aggarwal, Nitin T; Shi, Nian-Qing; Makielski, Jonathan C

    2013-01-01

    Cardiac ATP-sensitive potassium channels (KATP) are found in both the sarcoplasmic reticulum (sarcKATP) and the inner membrane of mitochondria (mitoKATP). SarcKATP are composed of a pore containing subunit Kir6.2 and a regulatory sulfonylurea receptor subunit (SUR2), but the composition of mitoKATP remains unclear. An unusual intra-exonic splice variant of SUR2 (SUR2A-55) was previously identified in mitochondria of mammalian heart and brain, and by analogy with sarcKATP we proposed SUR2A-55 as a candidate regulatory subunit of mitoKATP. Although SUR2A-55 lacks the first nucleotide binding domain (NBD) and 2 transmembrane domains (TMD), it has a hybrid TMD and retains the second NBD. It resembles a hemi-ABC transporter suggesting it could multimerize to function as a regulatory subunit. A putative mitochondrial targeting signal in the N-terminal domain of SUR2A-55 was removed by truncation and when co-expressed with Kir6.1 and Kir6.2 it targeted to the plasma membrane and yielded KATP currents. Single channel conductance, mean open time, and burst open time of SUR2A-55 based KATP was similar to the full-length SUR2A based KATP. However, the SUR2A-55 KATP were 70-fold less sensitive to block by ATP, and twice as resistant to intracellular Ca2+ inhibition compared with the SUR2A KATP, and were markedly insensitive to KATP drugs, pinacidil, diazoxide, and glybenclamide. These results suggest that the SUR2A-55 based channels would tend to be open under physiological conditions and in ischemia, and could account for cardiac and mitochondrial phenotypes protective for ischemia. PMID:24037327

  3. SUR2A C-terminal fragments reduce KATP currents and ischaemic tolerance of rat cardiac myocytes

    PubMed Central

    Rainbow, RD; Lodwick, D; Hudman, D; Davies, NW; Norman, RI; Standen, NB

    2004-01-01

    C-terminal fragments of the sulphonylurea receptor SUR2A can alter the functional expression of cloned ATP-sensitive K+ channels (KATP). To investigate the protective role of KATP channels during metabolic stress we transfected SUR2A fragments into adult rat cardiac myocytes. A fragment comprising residues 1294–1358, the A-fragment, reduced sarcolemmal KATP currents by over 85% after 2 days (pinacidil-activated current densities were: vector alone 7.04 ± 1.22; and A-fragment 0.94 ± 0.07 pA pF−1, n = 6,6, P < 0.001). An inactive fragment (1358–1545, current density 6.30 ± 0.85 pA pF−1, n = 6) was used as a control. During metabolic inhibition (CN and iodoacetate) of isolated myocytes stimulated at 1 Hz, the A-fragment delayed action potential shortening and contractile failure, but accelerated rigor contraction and increased Ca2+ loading. On reperfusion, A-fragment-transfected cells also showed increased intracellular Ca2+ and the proportion of cells recovering contractile function was reduced from 40.0 to 9.5% (P < 0.01). The protective effect of pretreatment with 2,4-dinitrophenol, measured from increased functional recovery and reduced Ca2+ loading, was abolished by the A-fragment. Our data are consistent with a role for KATP channels in causing action potential failure and reduced Ca2+ loading during metabolic stress, and with a major role in protection by preconditioning. The effects of the A-fragment may arise entirely from reduced expression of the sarcolemmal KATP channel, but we also discuss the possibility of mitochondrial effects. PMID:15020694

  4. Promoting Colorectal Cancer Screening Discussion

    PubMed Central

    Christy, Shannon M.; Perkins, Susan M.; Tong, Yan; Krier, Connie; Champion, Victoria L.; Skinner, Celette Sugg; Springston, Jeffrey K.; Imperiale, Thomas F.; Rawl, Susan M.

    2013-01-01

    Background Provider recommendation is a predictor of colorectal cancer (CRC) screening. Purpose To compare the effects of two clinic-based interventions on patient–provider discussions about CRC screening. Design Two-group RCT with data collected at baseline and 1 week post-intervention. Participants/setting African-American patients that were non-adherent to CRC screening recommendations (n=693) with a primary care visit between 2008 and 2010 in one of 11 urban primary care clinics. Intervention Participants received either a computer-delivered tailored CRC screening intervention or a nontailored informational brochure about CRC screening immediately prior to their primary care visit. Main outcome measures Between-group differences in odds of having had a CRC screening discussion about a colon test, with and without adjusting for demographic, clinic, health literacy, health belief, and social support variables, were examined as predictors of a CRC screening discussion using logistic regression. Intervention effects on CRC screening test order by PCPs were examined using logistic regression. Analyses were conducted in 2011 and 2012. Results Compared to the brochure group, a greater proportions of those in the computer-delivered tailored intervention group reported having had a discussion with their provider about CRC screening (63% vs 48%, OR=1.81, p<0.001). Predictors of a discussion about CRC screening included computer group participation, younger age, reason for visit, being unmarried, colonoscopy self-efficacy, and family member/friend recommendation (all p-values <0.05). Conclusions The computer-delivered tailored intervention was more effective than a nontailored brochure at stimulating patient–provider discussions about CRC screening. Those who received the computer-delivered intervention also were more likely to have a CRC screening test (fecal occult blood test or colonoscopy) ordered by their PCP. Trial registration This study is registered at www

  5. Probabilistic inversion: a preliminary discussion

    NASA Astrophysics Data System (ADS)

    Battista Rossi, Giovanni; Crenna, Francesco

    2015-02-01

    We continue the discussion on the possibility of interpreting probability as a logic, that we have started in the previous IMEKO TC1-TC7-TC13 Symposium. We show here how a probabilistic logic can be extended up to including direct and inverse functions. We also discuss the relationship between this framework and the Bayes-Laplace rule, showing how the latter can be formally interpreted as a probabilistic inversion device. We suggest that these findings open a new perspective in the evaluation of measurement uncertainty.

  6. Availability of safe drinking-water: the answer to cholera outbreak? Nabua, Camarines Sur, Philippines, 2012

    PubMed Central

    de los Reyes, Vikki Carr; Sucaldito, Ma Nemia; Tayag, Enrique

    2015-01-01

    Background In May 2012, there were increasing diarrhoea cases and deaths reported from Nabua, Camarines Sur to the Philippines event-based surveillance system. An investigation was conducted to identify risk factors and determine transmission dynamics. Methods A suspected case was defined as a resident of Nabua with at least three episodes of watery diarrhoea per day from 16 March to 22 June 2012. A confirmed case was defined as a suspected case positive for Vibrio cholerae. An environmental investigation was conducted and rectal swabs and water samples sent to the national reference laboratory for bacterial isolation. A 1:2 case-control study matching for age and sex was conducted. Data were analysed using Epi Info. Results There were 309 suspected cases with two deaths, and the most affected age group was children under five years (45%). Eight cases were positive for Vibrio cholerae Ogawa El Tor and one for Non-01. Water samples were positive for faecal coliforms and Aeromonas caviae. The case-control study showed that cases had a higher odds than controls of using unchlorinated water sources (odds ratio [OR] = 3.6; 95% confidence interval [CI]:1.6–8.5) and having toilets located within 20 m of a septic tank (OR = 2.7; 95% CI: 1.4–5.3). In multivariate analysis, the only significant factor was drinking from piped water (OR = 0.21; 95% CI: 0.09–0.49). Discussion In this cholera outbreak, drinking-water from unchlorinated wells was a significant risk factor. Future cholera control efforts should include not just improving water and sanitation systems but also intensified behaviour change campaigns. PMID:26668761

  7. Space Launch System Panel Discussion

    NASA Image and Video Library

    2013-11-12

    Jim Crocker, Vice President and General Manager, civil space, Lockheed Martin Space Systems, gestures while speaking at a panel discussion on deep space exploration using the Space Launch System and Orion spacecraft at the Newseum in Washington on Tuesday, November 12, 2013. Photo Credit: (NASA/Jay Westcott)

  8. Another Discussion about Academic Corruption

    ERIC Educational Resources Information Center

    Changgeng, Li

    2007-01-01

    Academic corruption is a commonplace matter about which all people are clearly aware. However, people often overlook many hidden or latent manifestations of academic corruption. This article discusses eight of these manifestations: indiscriminate use of the academic team spirit, the proliferation of "word games," deliberate attacks on…

  9. Body Art: A Panel Discussion.

    ERIC Educational Resources Information Center

    Surgenor, Peter; And Others

    1997-01-01

    Three camp directors discuss their policies regarding body art and body piercing. Only one director reported a strict policy prohibiting tattoos or body art based on standards that the camp portrays to families. However, all directors enforced policies prohibiting clothing or body art that mentions alcohol, tobacco, drug use, or inappropriate…

  10. Lively Discussions! Fostering Engaged Reading.

    ERIC Educational Resources Information Center

    Gambrell, Linda B., Ed.; Almasi, Janice F., Ed.

    Offering practical, classroom-based strategies teachers can use to promote literacy development, this book presents many examples of children engaging in discussion activities about narrative and informational text that emphasize collaborating, constructing meaning, and using these different types of texts to arrive at new understandings. Chapters…

  11. Linguistic Indexicality in Algebra Discussions

    ERIC Educational Resources Information Center

    Staats, Susan; Batteen, Chris

    2010-01-01

    In discussion-oriented classrooms, students create mathematical ideas through conversations that reflect growing collective knowledge. Linguistic forms known as indexicals assist in the analysis of this collective, negotiated understanding. Indexical words and phrases create meaning through reference to the physical, verbal and ideational context.…

  12. Lively Discussions! Fostering Engaged Reading.

    ERIC Educational Resources Information Center

    Gambrell, Linda B., Ed.; Almasi, Janice F., Ed.

    Offering practical, classroom-based strategies teachers can use to promote literacy development, this book presents many examples of children engaging in discussion activities about narrative and informational text that emphasize collaborating, constructing meaning, and using these different types of texts to arrive at new understandings. Chapters…

  13. Body Art: A Panel Discussion.

    ERIC Educational Resources Information Center

    Surgenor, Peter; And Others

    1997-01-01

    Three camp directors discuss their policies regarding body art and body piercing. Only one director reported a strict policy prohibiting tattoos or body art based on standards that the camp portrays to families. However, all directors enforced policies prohibiting clothing or body art that mentions alcohol, tobacco, drug use, or inappropriate…

  14. What Is Effectiveness? Panel Discussion.

    ERIC Educational Resources Information Center

    Zigmond, Naomi

    Two papers are presented from a panel discussion moderated by Naomi Zigmond, who introduces the papers with a note on definitions and measures of intervention effectiveness. "Some Thoughts on Effective Intervention for Handicapped Preschoolers," by Phillip Strain, notes that special education researchers attempt to be efficient, economical,…

  15. Another Discussion about Academic Corruption

    ERIC Educational Resources Information Center

    Changgeng, Li

    2007-01-01

    Academic corruption is a commonplace matter about which all people are clearly aware. However, people often overlook many hidden or latent manifestations of academic corruption. This article discusses eight of these manifestations: indiscriminate use of the academic team spirit, the proliferation of "word games," deliberate attacks on…

  16. Five Discussions on Postsecondary Education.

    ERIC Educational Resources Information Center

    Jobe, E. R., Ed.

    Topics discussed are: (1) student aid and access to postsecondary education (Jack L. Woodward); (2) values in athletics (Grant Dungee); (3) some considerations in planning for postsecondary education (Paul G. Orr); (4) the open university as a challenge for postsecondary education in Mississippi (Cleopatra D. Thompson); and (5) comprehensive…

  17. Enhancing Discussion through Short Stories.

    ERIC Educational Resources Information Center

    Marcus, Sybil

    A teacher of English in a college-level intensive English language program describes a method for stimulating speech in high-intermediate and advanced students, using short stories. It is argued that in short stories, the themes are universal, and even shy students are willing to discuss this form of literature in class. Criteria for selecting…

  18. A Study in Structured Discussion.

    ERIC Educational Resources Information Center

    Gutzmer, Willard Ernest

    This study tested the hypothesis that group interaction skill and useful learning occur in a discussion group which is academically structured. A class procedure involving a cognitive map, member skills and roles, and group etiquette was incorporated into a class ("Education and the Contemporary Scene," Fall Quarter, 1968) at the…

  19. Argumentative Reasoning in Online Discussion.

    ERIC Educational Resources Information Center

    Steinkuehler, Constance A.; Derry, Sharon J.; Levin, Joel R.; Kim, Jong-Baeg

    This study compared the effects of three forms of online instruction on memory, belief change, and argumentation skill. Reading of a pro/con text was followed by: (1) online discussion in pairs compared to reading of the same text followed by two forms of individualized study techniques derived from the cognitive memory literature; (2)…

  20. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH.

    PubMed

    Mohammed Abdul, Khaja Shameem; Jovanović, Sofija; Du, Qingyou; Sukhodub, Andriy; Jovanović, Aleksandar

    2015-05-01

    High-altitude residents have lower mortality rates for ischaemic heart disease and this is ascribed to cardiac gene remodelling by chronic hypoxia. SUR2A is a cardioprotective ABC protein serving as a subunit of sarcolemmal ATP-sensitive K(+) channels. The purpose of this study was to determine whether SUR2A is regulated by mild hypoxia in vivo and to elucidate the underlying mechanism. Mice were exposed to either 21% (control) or 18% (mild hypoxia) oxygen for 24h. Exposure to 18% oxygen did not affect partial pressure of O(2) (PO(2)) and CO(2) (PCO(2)) in the blood, haematocrit or level of ATP in the heart. However, hypoxia increased myocardial lactate dehydrogenase (LDH) and lactate as well as NAD(+) without affecting total NAD. SUR2A levels were significantly increased as well as myocardial resistance to ischaemia-reperfusion. Exposure to 18% oxygen did not phosphorylate extracellular signal regulated kinases (ERK1/2) or AMP activated protein kinase (AMPK), but it phosphorylated protein kinase B (Akt). An inhibitor of phosphoinositide 3-kinases (PI3K), LY294002 (0.2mg/mouse), abolished all observed effects of hypoxia. LDH inhibitors, galloflavin (50 μM) and sodium oxamate (80 mM) significantly decreased levels of SUR2A in heart embryonic H9c2 cells, while inactive mutant LDH form, gly193-M-LDH increased cellular sensitivity towards stress induced by 2,4-dinitrophenol (10mM). Treatment of H9c2 cells with sodium lactate (30 mM) increased intracellular lactate, but did not affect LDH activity or SUR2A levels. We conclude that PI3K/Akt signalling pathway and LDH play a crucial role in increase of cardiac SUR2A induced by in vivo exposure to 18% oxygen. Copyright © 2015. Published by Elsevier B.V.

  1. Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels.

    PubMed

    Muñoz, Alvaro; Nakazaki, Mitsuhiro; Goodman, J Clay; Barrios, Roberto; Onetti, Carlos G; Bryan, Joseph; Aguilar-Bryan, Lydia

    2003-01-01

    ATP-sensitive K+ (K(ATP)) channels have been implicated in the mechanism of neuronal ischemic preconditioning. To evaluate the role of neuronal/beta-cell-type K(ATP) channels, SUR1 null (Sur1KO) mice lacking (K(IR)6.x/SUR1)(4) K(ATP) channels were subjected to a preconditioning protocol with the use of double carotid occlusion. Wild-type C57BL/6 and Sur1KO mice were subjected to a double carotid block for 40 minutes with or without a 20-minute preconditioning block. After a 10-day reperfusion period, damage was assessed histologically in the hippocampal CA1, CA2, and CA3 areas and in the dentate gyrus. The neuroprotective effects of intracerebroventricular injections of diazoxide, which selectively affects mitochondria versus opening SUR1-type K(ATP) channels, and 5-hydroxydecanoate, a selective blocker of mitoK(ATP) channels, were evaluated with the same protocol. Neurons in the CA1 region of both Sur1KO and wild-type animals subjected to a 20-minute ischemic insult were protected equally from neuronal damage produced by a subsequent 40-minute ischemic period. Pretreatment with diazoxide protected both Sur1KO and wild-type neurons, while 5-hydroxydecanoate augmented neurodegeneration in both strains of animals when administered before a 20-minute bout of ischemia. SUR1-based K(ATP) channels are not obligatory for neuronal preconditioning or augmentation of neurodegeneration by 5-hydroxydecanoate.

  2. Survival of Phytophthora ramorum following wildfires in the sudden oak death-impacted forests of the Big Sur region

    Treesearch

    Maia M. Beh; Margaret Metz; Kerri Frangioso; David Rizzo

    2013-01-01

    The summer of 2008 brought the first wildfires to occur in known Phytophthora ramorum-infested forests in California, with the largest individual fire burning in the Big Sur region of the central coast (Monterey County) (Metz et al. 2011). More than 100,000 ha in Big Sur were ultimately burned that summer, providing a natural experiment to examine...

  3. Influence du traitement thermique sur l'usinabilite du laiton monophase

    NASA Astrophysics Data System (ADS)

    Cholley, Airy

    La connaissance des proprietes et du comportement d'un materiau en usinage est primordiale pour optimiser son utilisation et obtenir une usinabilite maximale. Dans ce but, l'etude de la modification de la ductilite par traitement thermiques sur plusieurs criteres d'usinabilite tels que les efforts de coupe, la rugosite, les bavures et la formation du copeau a ete menee sur le laiton monophase. A cette fin, l'influence du traitement thermique sur la microstructure du laiton a d'abord ete etudiee. La taille des grains et la durete ont permis de determiner les proprietes mecaniques des etats metallurgiques. Des essais de percage ont ensuite ete effectues sur les etats metallurgiques H01 (99HV), OS100 (88HV) et OS250 (47HV) pour regarder l'influence du traitement thermique sur l'usinabilite. Cette etude experimentale a permis de comprendre l'influence du taux de laminage et de la temperature de recuit sur les proprietes mecaniques. Les essais d'usinabilite ont ensuite permis de prouver que les efforts de coupe sont dependants des conditions de coupe mais pas de la ductilite dans les etats metallurgiques testes. La taille des bavures augmente avec la ductilite et la vitesse de coupe, et diminue avec l'avance. La rugosite de la surface des trous apres l'usinage a egalement ete etudiee. Il a aussi ete prouve par une etude sur les copeaux que la temperature croit avec la vitesse de coupe. L'analyse de la segmentation des copeaux n'a en revanche pas permis de trouver une correlation significative avec les traitements thermiques testes. Enfin, le revetement de l'outil a montre une grande importance sur l'usinabilite du materiau. Il a ete conclu que l'usinabilite du laiton C26000 (CuZn30) est meilleure lorsqu'on travaille dans un etat metallurgique dur. Ces conclusions sont valables pour le laiton monophase etudie, il serait interessant d'examiner aussi le cas des laitons biphases.

  4. Demonstration of the Marine Towed Array on Bahia Salinas del Sur Vieques, Puerto Rico

    DTIC Science & Technology

    2009-02-01

    Manne Towed Array cooducted a MEC sur ey of the Sahli Salinas del Sur and adjacent areas . The Bahia encompasses an area of 0.5)(0.75 nautical miles...Waler depths ~ary from breakmg surf to Slightly over 30 ft. The bay bottom consists of areas of open sand, areas covered bymarine sea grasses, and...Naval gunfire. The entire Bahia lies within the Live Impact Area 01 a former Naval training range, which was used for over 50 years by ships and

  5. Group discussion improves lie detection

    PubMed Central

    Klein, Nadav; Epley, Nicholas

    2015-01-01

    Groups of individuals can sometimes make more accurate judgments than the average individual could make alone. We tested whether this group advantage extends to lie detection, an exceptionally challenging judgment with accuracy rates rarely exceeding chance. In four experiments, we find that groups are consistently more accurate than individuals in distinguishing truths from lies, an effect that comes primarily from an increased ability to correctly identify when a person is lying. These experiments demonstrate that the group advantage in lie detection comes through the process of group discussion, and is not a product of aggregating individual opinions (a “wisdom-of-crowds” effect) or of altering response biases (such as reducing the “truth bias”). Interventions to improve lie detection typically focus on improving individual judgment, a costly and generally ineffective endeavor. Our findings suggest a cheap and simple synergistic approach of enabling group discussion before rendering a judgment. PMID:26015581

  6. Group discussion improves lie detection.

    PubMed

    Klein, Nadav; Epley, Nicholas

    2015-06-16

    Groups of individuals can sometimes make more accurate judgments than the average individual could make alone. We tested whether this group advantage extends to lie detection, an exceptionally challenging judgment with accuracy rates rarely exceeding chance. In four experiments, we find that groups are consistently more accurate than individuals in distinguishing truths from lies, an effect that comes primarily from an increased ability to correctly identify when a person is lying. These experiments demonstrate that the group advantage in lie detection comes through the process of group discussion, and is not a product of aggregating individual opinions (a "wisdom-of-crowds" effect) or of altering response biases (such as reducing the "truth bias"). Interventions to improve lie detection typically focus on improving individual judgment, a costly and generally ineffective endeavor. Our findings suggest a cheap and simple synergistic approach of enabling group discussion before rendering a judgment.

  7. Discussions on Hypnosis and Schizophrenia.

    PubMed

    Haley, Jay

    2015-01-01

    A classic paper in intellect and argument, this article contains a transcript of a conversation between Jay Haley, John Weakland, and Milton Erickson as they discuss the role of communication in hypnosis and schizophrenia. In 1955, schizophrenia was considered primarily a psychological disorder. Whereas today schizophrenia is mostly considered a biological disorder, this very early, unpublished paper still gives much food for thought and a further glimpse into Haley and Erickson's thinking and intellect at a fervent time in schizophrenia research.

  8. Discussion boards: boring no more!

    PubMed

    Adelman, Deborah S; Nogueras, Debra J

    2013-01-01

    Creating discussion boards (DBs) that capture student imaginations and contain meaningful interactions can be a difficult process. Traditional DBs use a question-and-answer format that often is boring for both the student and instructor. The authors present creative approaches to DBs that result in lively debates and student-to-student and student-to-faculty interactions, including role playing, blogging, wikis, and the use of voice.

  9. Space Launch System Panel Discussion

    NASA Image and Video Library

    2013-11-12

    L-R: William Gerstenmaier, NASA Associate Administrator for human exploration and operations; Charlie Precourt, Vice President and General Manager, ATK Space Launch Division; John Elbon, Vice President and General Manager, Boeing Space Exploration; Julie Van Kleek, Vice President, space programs, Aerojet Rocketdyne; and Jim Crocker, Vice President and General Manager, civil space, Lockheed Martin Space Systems, participate in a panel discussion on deep space exploration using the Space Launch System and Orion spacecraft at the Newseum in Washington on Tuesday, November 12, 2013. Photo Credit: (NASA/Jay Westcott)

  10. Axelrod model: accepting or discussing

    NASA Astrophysics Data System (ADS)

    Dybiec, Bartlomiej; Mitarai, Namiko; Sneppen, Kim

    2012-10-01

    Agents building social systems are characterized by complex states, and interactions among individuals can align their opinions. The Axelrod model describes how local interactions can result in emergence of cultural domains. We propose two variants of the Axelrod model where local consensus is reached either by listening and accepting one of neighbors' opinion or two agents discuss their opinion and achieve an agreement with mixed opinions. We show that the local agreement rule affects the character of the transition between the single culture and the multiculture regimes.

  11. Science leaders discuss budget crunch

    NASA Astrophysics Data System (ADS)

    Although funding for research fared relatively well in the budget proposed by the Reagan Administration for fiscal year (FY) 1987, leaders of the science community should expect lean times ahead for federal funding and should plan accordingly. This was the message delivered February 26-27, 1986, to nearly 400 participants in a conference at the National Academy of Sciences (NAS) in Washington, D.C.Leaders and policymakers from all segments of the research establishment were invited to attend the 2-day conference, which was sponsored by the Government-University-Industry Research Roundtable, an independent group associated with NAS, the National Academy of Engineering, and the Institute of Medicine. Discussions at the conference revolved around the question “What research strategies best serve the national interest in a period of budgetary stress?” After hearing perspectives from representatives from the Administration, industry, federal agencies, universities, and a federal laboratory, participants were divided into seven working groups. Each group was assigned a topic of discussion, such as “Management at the Campus Level,” “The Relative Roles of Federal Laboratories and Outside Research Institutions,” and “Possible Non-Federal Sources of Support: States, Industry, and Foundations.” On the second day of the conference, the working group chairmen reported back to the conference at large.

  12. Identifying tsunami deposits using shell taphonomy: Sur lagoon, Oman

    NASA Astrophysics Data System (ADS)

    Donato, S.; Reinhardt, E.; Rothaus, R.; Boyce, J.

    2007-05-01

    On November 28th, 1945 an 8.1 magnitude earthquake focused in the eastern portion of the Makran subduction zone (Arabian Sea) generated a powerful tsunami that destroyed many coastal villages in Pakistan and India. Reports indicate that the tsunami also caused significant damage in Muscat, Oman, although its effects elsewhere in Oman are unknown. A thick bivalve dominated shell horizon was discovered inside the Sur lagoon, which is located on the eastern promontory of Oman (200 km south of Muscat). This shell deposit is significant because it is laterally extensive (> 1 km2), extends deep within the lagoon (>2 km), ranges in thickness from 5 - 25 cm at the sample localities, contains numerous subtidal and offshore bivalve species, and articulated subtidal and offshore bivalve species are abundant. Although there is an absence of typical tsunami indicators such as allochthonous sediment in and around the lagoon, verbal accounts, cultural evidence recovered during coring, and the absence of strong storms during the past 100 years indicates that this shell unit was caused by the 1945 tsunami. In this setting, it would be advantageous to have another proxy for tsunami detection and risk prediction. The use of shell taphonomy is one of the potential indicators and here we present new evidence of its utility. We sampled this unit in eight locations, and compared the shell taphonomy to surface shell samples collected from beach and reworked horizons in the lagoon, and to shell samples from a known tsunami and corresponding storm/ballast deposit in Israel (Reinhardt et al., 2006). Taphonomic analysis yielded promising results, as the two tsunami horizons shared excellent agreement between the amount of fragmented shells, and the percentage of shells displaying angular breaks. Both of these categories were significantly different from the percentage of fragments and angular fragments recovered from the reworked, beach, and storm/ballast deposits, indicating different

  13. The Classroom as Big Sur: Notes on the Liaison Between Evaluation and Professional Growth

    ERIC Educational Resources Information Center

    Sneeden, Ralph

    2013-01-01

    Bill Frisell's new album ("Big Sur") was heralded with a short documentary about its impulse and inception: Frisell's retreat to an isolated coastal ranch in Central California. In the video, he describes the influence of the place, the dramatic and evocative landscape, and how it ultimately became the subject and theme for the…

  14. The Classroom as Big Sur: Notes on the Liaison Between Evaluation and Professional Growth

    ERIC Educational Resources Information Center

    Sneeden, Ralph

    2013-01-01

    Bill Frisell's new album ("Big Sur") was heralded with a short documentary about its impulse and inception: Frisell's retreat to an isolated coastal ranch in Central California. In the video, he describes the influence of the place, the dramatic and evocative landscape, and how it ultimately became the subject and theme for the…

  15. The Proposed Creation of University System in the Province of Ilocos Sur, Philippines

    ERIC Educational Resources Information Center

    Alviento, Severino G.

    2017-01-01

    This study aimed to determine the level of acceptability of the proposed amalgamation of the three Public Higher Education Institutions in Ilocos Sur. It employed the descriptive method of research. The respondents of the study are the 3rd and 4th year AB Political Science and BSE major in Social Science students and the 4th year BEED students of…

  16. Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

    ERIC Educational Resources Information Center

    Paskevska, Anna

    2007-01-01

    This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)

  17. Seafloor Rocks and Sediments of the Continental Shelf From Monterey Bay to Point Sur, California

    USGS Publications Warehouse

    Eittreim, Stephen L.; Anima, Roberto J.; Stevenson, Andrew J.; Wong, Florence L.

    2000-01-01

    Introduction Acoustic swath mapping of the greater Monterey Bay area continental shelf from Point Ano Nuevo to Point Sur reveals complex patterns of rock outcrops on the shelf, and coarse sand bodies that occur in distinct depressions on the inner and mid-shelves. This publication portrays the seafloor components in a 36- by 48-inch map sheet at 1:100,000 scale.

  18. Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

    ERIC Educational Resources Information Center

    Paskevska, Anna

    2007-01-01

    This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)

  19. Quantification of sudden oak death tree mortality in the Big Sur ecoregion of California

    Treesearch

    Douglas A. Shoemaker; Christopher B. Oneal; David M. Rizzo; Ross K. Meentemeyer

    2008-01-01

    Big Sur is one of the most ecologically diverse regions in California and well recognized as a biodiversity hotspot for global conservation priority. Currently the region is experiencing substantial environmental change due to the invasion of Phytophthora ramorum, the plant pathogen causing the forest disease known as sudden oak death. First...

  20. Discussing epigenetics in Southern California

    PubMed Central

    2012-01-01

    With the goal of discussing how epigenetic control and chromatin remodeling contribute to the various processes that lead to cellular plasticity and disease, this symposium marks the collaboration between the Institut National de la Santé et de la Recherche Médicale (INSERM) in France and the University of California, Irvine (UCI). Organized by Paolo Sassone-Corsi (UCI) and held at the Beckman Center of the National Academy of Sciences at the UCI campus December 15–16, 2011, this was the first of a series of international conferences on epigenetics dedicated to the scientific community in Southern California. The meeting also served as the official kick off for the newly formed Center for Epigenetics and Metabolism at the School of Medicine, UCI (http://cem.igb.uci.edu). PMID:22414797

  1. Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans

    PubMed Central

    Wang, Hong X.; Douglas, Lois M.; Veselá, Petra; Rachel, Reinhard; Malinsky, Jan; Konopka, James B.

    2016-01-01

    The plasma membrane of the fungal pathogen Candida albicans forms a protective barrier that also mediates many processes needed for virulence, including cell wall synthesis, invasive hyphal morphogenesis, and nutrient uptake. Because compartmentalization of the plasma membrane is believed to coordinate these diverse activities, we examined plasma membrane microdomains termed eisosomes or membrane compartment of Can1 (MCC), which correspond to ∼200-nm-long furrows in the plasma membrane. A pil1∆ lsp1∆ mutant failed to form eisosomes and displayed strong defects in plasma membrane organization and morphogenesis, including extensive cell wall invaginations. Mutation of eisosome proteins Slm2, Pkh2, and Pkh3 did not cause similar cell wall defects, although pkh2∆ cells formed chains of furrows and pkh3∆ cells formed wider furrows, identifying novel roles for the Pkh protein kinases in regulating furrows. In contrast, the sur7∆ mutant formed cell wall invaginations similar to those for the pil1∆ lsp1∆ mutant even though it could form eisosomes and furrows. A PH-domain probe revealed that the regulatory lipid phosphatidylinositol 4,5-bisphosphate was enriched at sites of cell wall invaginations in both the sur7∆ and pil1∆ lsp1∆ cells, indicating that this contributes to the defects. The sur7∆ and pil1∆ lsp1∆ mutants displayed differential susceptibility to various types of stress, indicating that they affect overlapping but distinct functions. In support of this, many mutant phenotypes of the pil1∆ lsp1∆ cells were rescued by overexpressing SUR7. These results demonstrate that C. albicans eisosomes promote the ability of Sur7 to regulate plasma membrane organization. PMID:27009204

  2. Intramolecular interaction of SUR2 subtypes for intracellular ADP-Induced differential control of K(ATP) channels.

    PubMed

    Matsushita, Kenji; Kinoshita, Kengo; Matsuoka, Tetsuro; Fujita, Akikazu; Fujikado, Takashi; Tano, Yasuo; Nakamura, Haruki; Kurachi, Yoshihisa

    2002-03-22

    ATP-sensitive K+ (K(ATP)) channels are composed of sulfonylurea receptors (SURs) and inwardly rectifying Kir6.2-channels. The C-terminal 42 amino acid residues (C42) of SURs are responsible for ADP-induced differential activation of K(ATP) channels in SUR-subtypes. By examining ADP-effect on K(ATP) channels containing various chimeras of SUR2A and SUR2B, we identified a segment of 7 residues at central portion of C42 critical for this phenomenon. A 3-D structure model of the region containing the second nucleotide-binding domain (NBD2) of SUR and C42 was developed based on the structure of HisP, a nucleotide-binding protein forming the bacterial Histidine transporter complex. In the model, the polar and charged residues in the critical segment located within a distance that allows their electrostatic interaction with Arg1344 at the Walker-A loop of NBD2. Therefore, the interaction might be involved in the control of ADP-induced differential activation of SUR2-subtype K(ATP) channels.

  3. To discuss illicit nuclear trafficking

    SciTech Connect

    Balatsky, Galya I; Severe, William R; Wallace, Richard K

    2010-01-01

    The Illicit nuclear trafficking panel was conducted at the 4th Annual INMM workshop on Reducing the Risk from Radioactive and Nuclear Materials on February 2-3, 2010 in Washington DC. While the workshop occurred prior to the Nuclear Security Summit, April 12-13 2010 in Washington DC, some of the summit issues were raised during the workshop. The Communique of the Washington Nuclear Security Summit stated that 'Nuclear terrorism is one of the most challenging threats to international security, and strong nuclear security measures are the most effective means to prevent terrorists, criminals, or other unauthorized actors from acquiring nuclear materials.' The Illicit Trafficking panel is one means to strengthen nuclear security and cooperation at bilateral, regional and multilateral levels. Such a panel promotes nuclear security culture through technology development, human resources development, education and training. It is a tool which stresses the importance of international cooperation and coordination of assistance to improve efforts to prevent and respond to incidents of illicit nuclear trafficking. Illicit trafficking panel included representatives from US government, an international organization (IAEA), private industry and a non-governmental organization to discuss illicit nuclear trafficking issues. The focus of discussions was on best practices and challenges for addressing illicit nuclear trafficking. Terrorism connection. Workshop discussions pointed out the identification of terrorist connections with several trafficking incidents. Several trafficking cases involved real buyers (as opposed to undercover law enforcement agents) and there have been reports identifying individuals associated with terrorist organizations as prospective plutonium buyers. Some specific groups have been identified that consistently search for materials to buy on the black market, but no criminal groups were identified that specialize in nuclear materials or isotope smuggling

  4. Discussion on selected symbiotic stars

    NASA Technical Reports Server (NTRS)

    Viotti, Roberto; Hack, Margherita

    1993-01-01

    Because of its large variety of aspects, the symbiotic phenomenon is not very suitable for a statistical treatment. It is also not clear whether symbiotic stars really represent a homogeneous group of astrophysical objects or a collection of objects of different natures but showing similar phenomena. However we are especially interested in the symbiotic phenomenon, i.e., in those physical processes occurring in the atmosphere of each individual object and in their time dependence. Such a research can be performed through the detailed analysis of individual objects. This study should be done for a time long enough to cover all the different phases of their activity, in all the spectral ranges. Since the typical time scale of the symbiotic phenomena is up to several years and decades, this represents a problem since, for instance, making astronomy outside the visual region is a quite new field of research. It was a fortunate case that a few symbiotic stars (Z And, AG Dra, CH Cyg, AX Per, and PU Vul) had undergone remarkable light variations (or 'outbursts') in recent years, which could have been followed in the space ultraviolet with IUE, and simultaneously in the optical and IR with ground-based telescopes. But, in general, the time coverage of most of the symbiotic objects is too short to have a complete picture of their behavior. In this regard, one should recall Mayall's remark about the light curve of Z And: 'Z Andromedae is another variable that shows it will require several hundred years of observations before a good analysis can be made of its variations'. This pessimistic remark should be considered as a note of caution for those involved in the interpretation of the observations. We shall discuss a number of individual symbiotic stars for which the amount of observational data is large enough to draw a rather complete picture of their general behavior and to make consistent models. We shall especially illustrate the necessary steps toward an empirical model

  5. Terry Quist Discusses Skylab Experiment

    NASA Technical Reports Server (NTRS)

    1972-01-01

    San Antonio, Texas high school student, Terry C. Quist (left), and Dr. Raymond Gause of the Marshall Space Flight Center (MSFC), discuss the student's experiment to be performed aboard the Skylab the following year. His experiment, 'Earth Orbital Neutron Analysis' required detectors such as the one he is examining in this photo. The detector was to be attached to a water tank in Skylab. Neutrons striking the detectors left traces that were brought out by a chemical etching process after the Skylab mission. Quist's experiment seeked to record neutron hits, count them, and determine their direction. This information was to help determine the source of neutrons in the solar system. Quist was among 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. The nationwide scientific competition was sponsored by the National Science Teachers Association and the National Aeronautics and Space Administration (NASA). The winning students, along with their parents and sponsor teachers, visited MSFC two months earlier where they met with scientists and engineers, participated in design reviews for their experiments, and toured MSFC facilities. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of additional equipment. The equipment for the experiments was manufactured at MSFC.

  6. Discussion summary: Fictitious domain methods

    NASA Technical Reports Server (NTRS)

    Glowinski, Rowland; Rodrigue, Garry

    1991-01-01

    Fictitious Domain methods are constructed in the following manner: Suppose a partial differential equation is to be solved on an open bounded set, Omega, in 2-D or 3-D. Let R be a rectangle domain containing the closure of Omega. The partial differential equation is first solved on R. Using the solution on R, the solution of the equation on Omega is then recovered by some procedure. The advantage of the fictitious domain method is that in many cases the solution of a partial differential equation on a rectangular region is easier to compute than on a nonrectangular region. Fictitious domain methods for solving elliptic PDEs on general regions are also very efficient when used on a parallel computer. The reason is that one can use the many domain decomposition methods that are available for solving the PDE on the fictitious rectangular region. The discussion on fictitious domain methods began with a talk by R. Glowinski in which he gave some examples of a variational approach to ficititious domain methods for solving the Helmholtz and Navier-Stokes equations.

  7. Que nous apprennent les petits frères et sœurs sur les signes précoces d’autisme?1

    PubMed Central

    Rogers, Sally J.

    2010-01-01

    L’objectif de cette revue est de présenter une synthèse des réponses que l’on peut actuellement apporter à la question de savoir quelles sont les premières caractéristiques comportementales qui prédisent le développement de l’autisme. L’article se centre sur 5 points : la présence de Troubles du Spectre Autistique (TSA) dans des groupes de frères et sœurs puînés d’enfants déjà diagnostiqués, les patterns et caractéristiques du développement moteur, les patterns et caractéristiques du développement social et émotionnel, les patterns et caractéristiques de la communication intentionnelle verbale et non verbale, et les patterns qui marquent le début de comportements pathognomoniques de TSA. La discussion porte sur les aspects inattendus des résultats et les pistes de recherche nouvelles qu’ils peuvent engendrer. PMID:20890377

  8. The Palaeodiet of the Pericue Indians of the Cape Region of Baja California Sur, Mexico.

    NASA Astrophysics Data System (ADS)

    Beer, N.; Gonzalez, S.; Huddart, D.; Rosales-Lopez, A.; Lamb, A.

    2008-05-01

    The archaeology of the Pericue Indians inhabiting the Cape region of Baja California has long been an area of interest. The dolichocranic traits exhibited by this population have lead to suggestions that these people were a relic population of an early coastal migration into North America. The antiquity of directly dated Pericue human remains only reaches 3,000 B.P. with occupation sites dating back to 9,000 B.P. The site of Babisuri cave in Isla Espiritu Santo may demonstrate a very early human presence in Baja California Sur between 36,000 to 45,000 B.P. although the exact nature of this evidence is unclear. Increasing tourist development within this region threatens many archaeological sites particularly coastal shell middens and rock shelters. Current rescue excavations are yielding important information regarding many aspects of the culture of the Pericue Indians. Geochemical evidence of diet {d13C and d15N} taken from Pericue bone samples, modern and archaeological animals and modern plants is helping us to understand the complicated subsistence strategies of this group. Initial results highlight a complicated and diverse diet including marine and terrestrial resources, most likely exploited seasonally. Similarities between the diet of the Pericue and other nearby coastal Indian groups are clear and will be discussed. Pericue Indian material culture, combined with the exploitation of marine mammals and the construction of enormous shell mounds display parallels with other central and North American groups. The exploitation of marine mammals and the associated stone tools display striking similarities to the Chumash people of the Channel Islands of Coastal Southern California. Some of these cultural similarities will be highlighted in this presentation. Current genetic work is attempting to discover the nature of the similarities between the Chumash and Pericue groups as some cultural elements of each group have parallels with the other. Initial genetic

  9. Signes sur des pistes pedagogiques (Signs on Pedagogical Trails)

    ERIC Educational Resources Information Center

    Porcher, Louis

    1978-01-01

    An overview of the topics in this issue. The place of authentic documents; their use in promoting communicative competence; new uses of visuals, such as cartoons; visuals for evaluation purposes; their cultural value; and the development of video-cassettes are discussed. (Text is in French.) (AMH)

  10. Questions sur les objectifs (Questions on the Objectives)

    ERIC Educational Resources Information Center

    Porcher, Louis

    1975-01-01

    This article discusses instruction by objectives. Suggestions include relating objectives to the notion of evaluation, so that improvement in objectives implies change in examinations; making the objectives clear to the learner; and taking into account the changing needs of the learner at each stage of learning. (Text is in French.) (AM)

  11. Évolution des lignes directrices sur le traitement de la dyslipidémie

    PubMed Central

    John Bosomworth, N.

    2014-01-01

    Résumé Objectif Comprendre comment les nouvelles lignes directrices sur la prise en charge du risque cardiovasculaire publiées par l’American Heart Association et l’American College of Cardiology (AHA-ACC) peuvent être interprétées et utilisées dans le contexte canadien. Sources des données Les lignes directrices de l’AHA-ACC ont été examinées, de même que toutes les références. Des recherches indépendantes dans PubMed ont été effectuées pour inclure l’ajout aux statines d’autres antihyperlipidémiants et l’emploi de calculatrices médicales visant à aider le patient à comprendre. Message principal Les nouvelles lignes directrices de l’AHA-ACC s’appuient sur les meilleures données probantes disponibles actuellement en matière de traitement de la dyslipidémie. Cela inclut le risque cardiovasculaire (CV) sur 10 ans comme seuil thérapeutique au lieu du taux de cholestérol des lipoprotéines de faible densité, de même que l’abandon des cibles thérapeutiques de lipoprotéines de faible densité. On met de plus en plus l’accent sur les interventions alimentaires et l’exercice, avec l’amorce d’un effort pour quantifier l’effet de ces interventions. Les statines constituent la principale intervention pharmacologique, et l’ajout d’autres médicaments pour accentuer la baisse lipidique n’est plus recommandé. En ce qui concerne l’application au Canada, les tables de risque de Framingham sont plus appropriées pour évaluer le risque que les équations de cohortes regroupées utilisées aux États-Unis. Les calculatrices du risque de maladie cardiovasculaire (MCV) devraient contenir de l’information sur l’âge cardiovasculaire et devraient pouvoir illustrer le risque et les interventions de rechange afin d’aider le patient à comprendre et de favoriser la prise de décision éclairée. Conclusion L’attention sur les meilleures données probantes concernant le risque CV peut simplifier le traitement de la

  12. [SENTIERI Project: discussion and conclusions].

    PubMed

    Pirastu, Roberta; Ricci, Paolo; Comba, Pietro; Bianchi, Fabrizio; Biggeri, Annibale; Conti, Susanna; Fazzo, Lucia; Forastiere, Francesco; Iavarone, Ivano; Martuzzi, Marco; Musmeci, Loredana; Pasetto, Roberto; Zona, Amerigo; Crocetti, Emanuele

    2014-01-01

    showing the increase, considering latency and the length of the observation period. Of further interest are results relating to diseases of the urinary tract such as kidney failure in the NPCSs of Basso bacino del fiume Chienti, Taranto, Milazzo and Priolo. Overall, the results discussed above are consistent with the previous findings pertaining to mortality for 1995-2002. The present analysis also introduces a new element - the study of cancer incidence and hospital discharges - which can tell us a great deal about diseases with high survival rates or non lethal ones. The first is the case of thyroid cancer, which presents increases in both databases and for both genders in a number of NPCSs (Brescia-Caffaro, Laghi di Mantova, Milazzo, Sassuolo- Scandiano and Taranto). The study of cancer incidence and hospital discharges also revealed cancer excesses for melanoma, breast cancer and non Hodgkin lymphoma in Brescia-Caffaro NPCS where PCBs (Polychlorinated biphenyl) are the site's main pollutant. PCBs, according to the 2013 evaluation of the International Agency for Research on Cancer, are ascertained human carcinogens for melanoma and probable carcinogens for breast cancer and non-Hodgkin lymphoma. The results pertaining to cancer incidence in the 17 NPCSs can also be presented using rankings by area or disease analyzed by a multivariate hierarchical Bayesian model. These rankings reveal an overlapping of credibility intervals, such that it is not possible to speak of a limited number of cancer sites or of certain NPCSs as being particularly affected. Every NPCS, therefore, must be considered individually and ordering them by ranking of cancer incidence wouldn't be appropriate. Data collected concerning some of the NPCSs in the context of the SENTIERI Project is so conclusive that remediation measures can immediately be put in place. This is the case in the Biancavilla and Brescia-Caffaro NPCSs. A similar conclusion can be drawn for complex locations such as Taranto

  13. A new species of Rhadinella (Serpentes: Colubridae) from the Sierra Madre del Sur of Guerrero, Mexico.

    PubMed

    Campillo, Gustavo; Dávila-Galavíz, Luis Fernando; Flores-Villela, Oscar; Campbell, Jonathan A

    2016-04-12

    We describe a new species of Rhadinella from the Sierra Madre del Sur of Guerrero, Mexico, a region where the genus was previously unknown. This diminutive species is a member of a group of snakes previously allocated in the Rhadinaea godmani group, and more recently transferred to the genus Rhadinella. These snakes may have conspicuous dark longitudinal striping on a pale brown to orange background or may have dark brown to blackish dorsal ground coloration, which mostly or completely obfuscates a pattern of longitudinal striping. The new species is mostly dark with barely discernible slightly paler or darker striping (depending on how striping is interpreted). The closest relative of the new species, on the basis of morphological similarities and biogeography, appears to be Rhadinella donaji which occurs to the east in the Sierra Madre del Sur of Oaxaca about 275 km from the type-locality of the new species.

  14. Influence des inclusions sur la rupture d'un acier faiblement allié

    NASA Astrophysics Data System (ADS)

    Hausild, P.; Berdin, C.; Bompard, P.; Prioul, C.

    2003-03-01

    L'étude de la rupture d'un acier faiblement allié dans le domaine de la transition ductile fragile a permis de mettre en évidence la présence croissante, avec la température de sollicitation, d'amas d'inclusions de seconde phase sur les surfaces de rupture. On montre, à l'aide de modélisations par éléments finis, que ces amas jouent néanmoins un rôle mineur dans le déclenchement du clivage. En revanche, leur influence sur la propagation de la rupture ductile est importante. On peut alors expliquer l'anisotropie de la résilience en prenant en compte la géométrie des inclusions et leur répartition spatiale.

  15. Réalisation de réseaux sur polymères par laser UV

    NASA Astrophysics Data System (ADS)

    Castex, M. C.; Fischer, A.; Simeonov, D.; Adès, D.; Siove, A.

    2003-06-01

    Nous présentons ici une méthode très simple de réalisation de réseaux d'amplitude de pas sub-micronique sur des films polymères à base de carbazote déposés sur des substrat de silice. Les réseaux sont fabriqués en irradiant avec un faisceau laser à 193nm un masque de phase placé au contact du film. La qualité des réseaux obtenus permet désormais d'envisager la réalisation de micro-cavités lasers de type planaire permettant de sélectionner une émission laser monomode autour de 400nm.

  16. The Nucleotide-Binding Sites of SUR1: A Mechanistic Model

    PubMed Central

    Vedovato, Natascia; Ashcroft, Frances M.; Puljung, Michael C.

    2015-01-01

    ATP-sensitive potassium (KATP) channels comprise four pore-forming Kir6.2 subunits and four modulatory sulfonylurea receptor (SUR) subunits. The latter belong to the ATP-binding cassette family of transporters. KATP channels are inhibited by ATP (or ADP) binding to Kir6.2 and activated by Mg-nucleotide interactions with SUR. This dual regulation enables the KATP channel to couple the metabolic state of a cell to its electrical excitability and is crucial for the KATP channel’s role in regulating insulin secretion, cardiac and neuronal excitability, and vascular tone. Here, we review the regulation of the KATP channel by adenine nucleotides and present an equilibrium allosteric model for nucleotide activation and inhibition. The model can account for many experimental observations in the literature and provides testable predictions for future experiments. PMID:26682803

  17. The Sur7 Protein Regulates Plasma Membrane Organization and Prevents Intracellular Cell Wall Growth in Candida albicans

    PubMed Central

    Alvarez, Francisco J.; Douglas, Lois M.; Rosebrock, Adam

    2008-01-01

    The Candida albicans plasma membrane plays important roles in cell growth and as a target for antifungal drugs. Analysis of Ca-Sur7 showed that this four transmembrane domain protein localized to stable punctate patches, similar to the plasma membrane subdomains known as eisosomes or MCC that were discovered in S. cerevisiae. The localization of Ca-Sur7 depended on sphingolipid synthesis. In contrast to S. cerevisiae, a C. albicans sur7Δ mutant displayed defects in endocytosis and morphogenesis. Septins and actin were mislocalized, and cell wall synthesis was very abnormal, including long projections of cell wall into the cytoplasm. Several phenotypes of the sur7Δ mutant are similar to the effects of inhibiting β-glucan synthase, suggesting that the abnormal cell wall synthesis is related to activation of chitin synthase activity seen under stress conditions. These results expand the roles of eisosomes by demonstrating that Sur7 is needed for proper plasma membrane organization and cell wall synthesis. A conserved Cys motif in the first extracellular loop of fungal Sur7 proteins is similar to a characteristic motif of the claudin proteins that form tight junctions in animal cells, suggesting a common role for these tetraspanning membrane proteins in forming specialized plasma membrane domains. PMID:18799621

  18. Characterization of surface antigen protein 1 (SurA1) from Acinetobacter baumannii and its role in virulence and fitness.

    PubMed

    Liu, Dong; Liu, Zeng-Shan; Hu, Pan; Cai, Ling; Fu, Bao-Quan; Li, Yan-Song; Lu, Shi-Ying; Liu, Nan-Nan; Ma, Xiao-Long; Chi, Dan; Chang, Jiang; Shui, Yi-Ming; Li, Zhao-Hui; Ahmad, Waqas; Zhou, Yu; Ren, Hong-Lin

    2016-04-15

    Acinetobacter baumannii is a Gram-negative bacillus that causes nosocomial infections, such as bacteremia, pneumonia, and meningitis and urinary tract and wound infections. In the present study, the surface antigen protein 1 (SurA1) gene of A. baumannii strain CCGGD201101 was identified, cloned and expressed, and then its roles in fitness and virulence were investigated. Virulence was observed in the human lung cancer cell lines A549 and HEp-2 at one week after treatment with recombinant SurA1. One isogenic SurA1 knock-out strain, GR0015, which was derived from the A. baumannii strain CCGGD201101 isolated from diseased chicks in a previous study, highlighted the effect of SurA1 on fitness and growth. Its growth rate in LB broth and killing activity in human sera were significantly decreased compared with strain CCGGD201101. In the Galleria mellonella insect model, the isogenic SurA1 knock-out strain exhibited a lower survival rate and decreased dissemination. These results suggest that SurA1 plays an important role in the fitness and virulence of A. baumannii.

  19. N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits

    PubMed Central

    Chan, Kim W.; Zhang, Hailin; Logothetis, Diomedes E.

    2003-01-01

    The sulfonylurea receptor (SUR), an ATP-binding cassette (ABC) protein, assembles with a potassium channel subunit (Kir6) to form the ATP-sensitive potassium channel (KATP) complex. Although SUR is an important regulator of Kir6, the specific SUR domain that associates with Kir6 is still unknown. All functional ABC proteins contain two transmembrane domains but some, including SUR and MRP1 (multidrug resistance protein 1), contain an extra N-terminal transmembrane domain called TMD0. The functions of any TMD0s are largely unclear. Using Xenopus oocytes to coexpress truncated SUR constructs with Kir6, we demonstrated by immunoprecipitation, single-oocyte chemiluminescence and electrophysiological measurements that the TMD0 of SUR1 strongly associated with Kir6.2 and modulated its trafficking and gating. Two TMD0 mutations, A116P and V187D, previously correlated with persistent hyperinsulinemic hypoglycemia of infancy, were found to disrupt the association between TMD0 and Kir6.2. These results underscore the importance of TMD0 in KATP channel function, explaining how specific mutations within this domain result in disease, and suggest how an ABC protein has evolved to regulate a potassium channel. PMID:12881418

  20. The Bacillus stearothermophilus NUB36 surA gene encodes a thermophilic sucrase related to Bacillus subtilis SacA.

    PubMed

    Li, Y; Ferenci, T

    1996-07-01

    The complete nucleotide sequence of the surA gene, encoding a sucrase from Bacillus stearothermophilus NUB36, was determined. surA was composed of 1338 bp and encoded 445 amino acid residues. The deduced polypeptide of M(r) 51519 showed strong sequence similarity to sucrose and sucrose phosphate hydrolases from Bacillus subtilis, Klebsiella pneumoniae and Vibrio alginolyticus, and contained the 'sucrose box' residues thought to be important for catalysis of the transfer of fructose from sucrose. The enzyme was partially purified using affinity chromotography from extracts of Escherichia coli containing the cloned surA. SurA displayed an optimum temperature for sucrose hydrolysis of 55 degrees C and high stability. The M(r) of SurA determined by gel filtration was 105,000, which suggested that the active form of the enzyme is a dimer. SurA exhibited an apparent Km of 40 mM for sucrose but, unlike the homologous B. subtilis enzyme, had no detectable sucrose phosphate hydrolase activity.

  1. Office of Naval Research (ONR) Support for R/V Point Sur Ship Operations

    DTIC Science & Technology

    2016-01-07

    WORK UNIT NUMBER N/A 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) San Jose State university Research Foundation 210 N. Fourth St...Enterprise Program Analyst San Jose State University Research Foundation Subject: ONR RV Pt Sur Award N00014-15-1 -2123 Enclosed is the Final...Marine Laboratories No longer employed at MLML Grant Administration: San Jose State University Research Foundation (SJSURF) 210 N. Fourth St. 4th

  2. Carcinome papillaire sur kyste du tractus thyréoglosse: à propos de deux cas

    PubMed Central

    Dbab, Lamia; Nouri, Hassan; Iguelouane, Nassim; Rochdi, Youssef; Aderdour, Lahcen; Raji, Abdelaziz

    2015-01-01

    L'objectif de ce travail est de présenté deux cas de carcinomes papillaire sur kystes du tractus thyréoglosse (KTT) et d'exposer notre attitude thérapeutique. Il s'agit de deux patientes, une âgée de 30 ans et l'autre de 45 ans, qui ont été opéré dans notre centre. Le diagnostic du carcinome papillaire sur KTT a été retenu après étude anatomopathologique du kyste après exérèse selon la technique de Sistrunk. Une thyroïdectomie totale suivie d'une irathérapie et d'une hormonothérapie freinatrice a été réalisé chez l'une des patientes, pour l'autre une thyroïdectomie totale associée à une hormonothérapie freinatrice a été préconisé. L'évolution été favorable après un recule de 4 ans pour la première patiente et de 2 ans pour la deuxième. La thyroïdectomie totale après exérèse complète du KTT est le traitement recommandé pour le carcinome papillaire sur KTT. Il a été démontré qu'un cancer latent de la thyroïde peut être développé même après des années après l'exérèse du KTT. Le traitement du carcinome papillaire sur KTT est bien codifié, permettant un excellent pronostic. PMID:26848352

  3. [Polyplacophoran communities (Mollusca: Polyplacophora) at Bahia de La Paz, Baja California Sur, México].

    PubMed

    García Ríos, Cedar I; Alvarez Ruiz, Migdalia

    2007-03-01

    Eight species of polyplacophorans have been reported from La Bahia de la Paz, Baja California Sur, Mexico. We add Lepidochitona beanii, Chaetopleura lurida, Stenoplax limaciformis, S. mariposa, Lepidozona clathrata, L. serrata and Acanthochitona arragonites, increasing the known number of species to 15. Ordination analysis of five chiton communities at the site suggests a correlation of wave exposure to species composition and diversity: communities with intermediate wave exposure have more species (richness) and higher diversity (Shannon's index).

  4. Transactive Discussions with Peers and Adults.

    ERIC Educational Resources Information Center

    Kruger, Ann Cale; Tomasello, Michael

    1986-01-01

    Investigates whether children's use of reasoning differs in child-child and adult-child discussions of moral dilemmas. Supports Piaget's contention that moral discussions with peers feature a more spontaneous use of reasoning than do discussions with adults. (HOD)

  5. Etude du stockage de l'hydrogene sur des nanostructures de carbone microporeuses

    NASA Astrophysics Data System (ADS)

    Poirier, Eric

    2007-12-01

    Le stockage de l'hydrogene par adsorption sur des adsorbants nano-structures a ete etudie sous differentes conditions de pression et de temperature. Les adsorbants etudies sont principalement des nanotubes de carbone a simple paroi ainsi que des structures metallo-organiques. Les mesures ont ete realisees a l'aide de systemes gravimetriques et volumetriques tres sensibles specialement mis au point pour de petits echantillons necessitant un degazage in situ. Les appareils developpes, au nombre de quatre, comprennent deux systemes gravimetriques et deux systemes volumetriques. Ensemble, ces systemes couvrent la plage de pressions (0-100) bars ainsi que la plage de temperatures (77-295) K. Les differentes analyses montrent que l'adsorption d'hydrogene sur les adsorbants nano-structures etudies est maximale a 77 K et varie entre environ (1.5 et 4) % masse. A temperature ambiante, l'adsorption croit lineairement avec la pression et demeure sous les 1% masse pour des pressions inferieures a 100 bars. L'adsorption d'hydrogene sur ces materiaux dans ces conditions se compare notamment a celle obtenue sur des charbons actives. La modelisation de l'adsorption a egalement ete realisee dans des conditions cryogeniques a l'aide du modele de Dubinin-Astakhov sous une forme adaptee pour l'adsorption supercritique. Les enthalpies d'adsorption calculees a partir de ce modele varient sous les 6 kJ/mole et sont donc consistantes avec des processus de physisorption. L'applicabilite du modele de Dubinin-Astakhov suggere que l'adsorption d'hydrogene puisse etre representee par un processus de remplissage des pores par un pseudo-liquide. Ces travaux s'inscrivent dans un contexte ou la capacite d'adsorption reelle des nanostructures de carbone est sujette a la controverse. En consequence, l'approche experimentale adoptee se distingue par les differentes demarches mises de l'avant pour l'obtention de mesures fiables sur des echantillons de faibles masses ainsi que par son caractere

  6. Change of Cerebral Oxygenation during Surfactant Treatment in Preterm Infants: "LISA" versus "InSurE" Procedures.

    PubMed

    Bertini, Giovanna; Coviello, Caterina; Gozzini, Elena; Bianconi, Tommaso; Bresci, Cecilia; Leonardi, Valentina; Dani, Carlo

    2017-04-01

    Objectives The aim of the study was to compare the effects on cerebral oxygenation in preterm infants of two different procedures for surfactant administration: the LISA (low-invasive method of surfactant administration) and the InSurE (Intubation, SURfactant administration, Extubation). Study Design Twenty premature infants with respiratory distress syndrome were assigned to receive surfactant either by "LISA" (n = 10) or "InSurE" (n = 10) procedure. Patients were continuously studied by near-infrared spectroscopy (NIRS) for the measurement of cerebral regional oxygenation (rSO2C) and calculation of cerebral fractional oxygen extraction rate (cFTOE), and NIRS data were recorded 30 minutes before (T0) surfactant administration, during the procedure (Tproc), and 30 (T1), 60 (T2T2), and 120 minutes (T3) afterward. Cerebral blood flow velocity (CBFV) was studied in the anterior cerebral artery at T0, T1, and T3. Results SpO2 significantly decreased at Tproc in comparison with T0, T1, T2, and T3 and the decrease was higher in the LISA than in the InSurE group. rSO2C was lower at tproc and T3 in the LISA than in the InSurE group. cFTOE was higher at tproc, t2, and t3 in the LISA group than in the InSurE group. CBFV did not change during the study periods in both groups. Conclusions The LISA and InSurE procedures transiently decreased rSO2C in our population, and the decrease was higher in the LISA group. Consistently, there was a contemporary increase in cFTOE that was higher in the LISA than in the InSurE group, suggesting that it represents a compensatory mechanism.

  7. Increasing Moral Reasoning Skills through Online Discussions

    ERIC Educational Resources Information Center

    Cain, Jeff; Smith, Doug

    2009-01-01

    This study examined the effects that online asynchronous dilemma discussions have on moral reasoning scores of pharmacy students. In contrast to face-to-face group discussions, asynchronous threaded discussions afford all participants time to reflect and respond during discussions. Anonymity features may lessen inhibitions in responding critically…

  8. Phenylephrine preconditioning in embryonic heart H9c2 cells is mediated by up-regulation of SUR2B/Kir6.2: A first evidence for functional role of SUR2B in sarcolemmal KATP channels and cardioprotection.

    PubMed

    Jovanović, Sofija; Ballantyne, Thomas; Du, Qingyou; Blagojević, Miloš; Jovanović, Aleksandar

    2016-01-01

    ATP-sensitive K(+) (KATP) channels were originally described in cardiomyocytes, where physiological levels of intracellular ATP keep them in a closed state. Structurally, these channels are composed of pore-forming inward rectifier, Kir6.1 or Kir6.2, and a regulatory, ATP-binding subunit, SUR1, SUR2A or SUR2B. SUR1 and Kir6.2 form pancreatic type of KATP channels, SUR2A and Kir6.2 form cardiac type of KATP channels, SUR2B and Kir6.1 form vascular smooth muscle type of KATP channels. The presence of SUR2B has been described in cardiomyocytes, but its functional significance and role has remained unknown. Pretreatment with phenylephrine (100nM) for 24h increased mRNA levels of SUR2B and Kir6.2, without affecting those levels of SUR1, SUR2A and Kir6.1 in embryonic heart H9c2 cells. Such increase was associated with increased K(+) current through KATP channels and Kir6.2/SUR2B protein complexes as revealed by whole cell patch clamp electrophysiology and immunoprecipitation/Western blotting respectively. Pretreatment with phenylephrine (100nM) generated a cellular phenotype that acquired resistance to chemical hypoxia induced by 2,4-dinitrophenol (DNP; 10mM), which was accompanied by increased in K(+) current in response to DNP (10mM). Cytoprotection afforded by phenylephrine (100nM) was abolished by infection of H9c2 cells with adenovirus containing Kir6.2AFA, a mutant form of Kir6.2 with largely reduced K(+) conductance. Taking all together, the present findings demonstrate that the activation of α1-adrenoceptors up-regulates SUR2B/Kir6.2 to confer cardioprotection. This is the first account of possible physiological role of SUR2B in cardiomyocytes.

  9. Etude sur les tendons en materiaux composites et leur application aux ancrages postcontraints

    NASA Astrophysics Data System (ADS)

    Chennouf, Adil

    L'objectif general de la presente these est d'evaluer le comportement a l'arrachement et au fluage d'ancrages injectes constitues de tendons en materiaux composites afin d'etablir des recommandations plus appropriees et realistes pour le dimensionnement et la conception. Quatre types de tendons en materiaux composites, deux a base de fibres d'aramide et deux a base de fibres de carbone, ont ete utilises dans l'etude. Les travaux de recherche de cette these ont porte notamment sur: (I) Une caracterisation physique et mecanique des tendons en materiaux composites utilises dans l'etude. (II) Une etude en laboratoire sur les coulis de scellement. La premiere etape de cette etude a concerne le developpement d'un coulis de scellement performant adapte aux tendons en materiaux composites et a differentes situations d'injection. La seconde etape a traite des essais de caracterisations physique et mecanique du coulis de scellement developpe comparativement a trois coulis de scellement usuels d'un meme rapport E/L de 0,4. (III) Une etude sur des modeles reduits d'ancrages injectes. (IV) Une etude sur des modeles d'ancrages a grande echelle. La synthese de ces etudes a permis d'enoncer les principales conclusions suivantes: (1) Les valeurs moyennes des charges de rupture des tendons en materiaux composites ont ete de 1% a 29% superieures a celles specifiees par les manufacturiers. (2) L'etude sur les coulis de scellement a permis le developpement de coulis de ciment repondant aux criteres fixes, soient une grande stabilite, une bonne fluidite, une legere expansion et de bonnes caracteristiques mecaniques. (3) Les tendons en materiaux composites ont montre des contraintes d'adherence maximum superieures a celles des tendons en acier. (4) Le type de fibre, la configuration et le fini de surface des tendons en materiaux composites gouvernent leur resistance a l'adherence. (5) L'introduction de sable et d'autres ajouts comme les fines de silice et la poudre d'aluminium au coulis

  10. Sur la reponse en frequence du tissu nerveux dans le cortex

    NASA Astrophysics Data System (ADS)

    Bedard, Claude

    Dans cette These de Physique, nous avons etudie la dependance en frequence du champ electrique du tissu nerveux dans le cortex. Ce champ est aussi designe par "Local field Potential" LFP dans la litterature scientifique. Cette etude est fondee sur la theorie du champ electromagnetisme de Maxwell et sur de l'information tiree de la donne experimentale. Le resultat essentiel de cette These est que la grandeur enorme du temps de relaxation de Maxwell des membranes cellulaires semble etre la cause principale de la dependance en frequence des LFPs. Cette dependance en frequence causee par chaque membrane cellulaire est l'analogue d'un circuit RC ou la resistance R est la resistivite parallele d'une membrane cellulaire, et ou la capacite C est la permittivite electrique de la membrane. L'effet resultant d'un tres grand nombre de cellules donne un spectre de Fourier dont l'enveloppe est tres pres d'un signal en 1/f. Le modele physique propose dans cette These permet de lier les mesures prises a l'interieur d'une dendrite des variations de potentiel electrique a celles prises dans le liquide extracellulaire. De plus, cette These semble ouvrir la possibilite de mesurer le temps de relaxation de Maxwell des membranes cellulaires a l'aide de la mesure de la reponse en frequence du potentiel electrique extracellulaire (LFP). Enfin, cette These permet de lever le voile sur un sujet peu etudie, principalement en raison de la difficulte que represente l'etude des phenomenes electriques dans des milieux complexes comme les tissus vivants. En particulier, le probleme du filtrage frequentiel du potentiel electrique extracellulaire est une propriete fondamentale du tissu nerveux et son origine n'est pas connue.

  11. Volvulus du grêle sur lipome du mésentère

    PubMed Central

    Mbaye, Papa Alassane; Faye, Aime Lakh; Sagna, Aloise; Ndoye, Ndeye Aby; Seck, Ndeye Fatou; Ndour, Oumar; Ngom, Gabriel

    2017-01-01

    Nous rapportons l'observation d'une fillette âgée de 7ans qui reçue dans un tableau de syndrome sub-occlusif avec une douleur abdominale aigue paroxystique siégeant au niveau de l'épigastre associée à des vomissements et un arrêt des matières. L'examen physique mettait en évidence une sensibilité à la palpation de l'épigastre. L'échographie abdominale a montré une formation tissulaire intra péritonéale mal limitée sans caractère vasculaire au doppler, exerçant un effet de masse sur les structures de voisinage ; les vaisseaux mésentériques étaient en position normale. A la tomodensitométrie cette masse correspondait à une formation lipomateuse bien limitée exerçant un effet de masse sur le caecum avec un volvulus du grêle. Le diagnostic de volvulus du grêle sur lipome mésentérique a été retenu. L'exploration chirurgicale confirmait ce diagnostic. Une détorsion grélique et une énucléation lipomateuse étaient réalisées. Les suites opératoires étaient simples après un recul de 6 mois. L'examen anatomopathologique confirmait la nature lipomateuse de la masse. PMID:28819497

  12. To Infuse New Thinking, Try Book Discussions.

    ERIC Educational Resources Information Center

    Smit, Gary M.

    2001-01-01

    Describes how one school superintendent started a book discussion group to provide his leadership team with an opportunity to read, review, and discuss books dealing with contemporary educational issues. Identifies some benefits for professional growth and organizational improvement. (PKP)

  13. Video 7 of 14: Classroom Discussion

    NASA Image and Video Library

    This video segment documents the follow-up discussion, in which students discuss the results of their test flights. The session demonstrates how the teacher uses the inquiry method to evaluate stud...

  14. Discussing Diabetes with Your Healthcare Provider

    MedlinePlus

    ... of this page please turn Javascript on. Feature: Diabetes Discussing Diabetes with Your Healthcare Provider Past Issues / Fall 2009 Table of Contents Diabetes Medicines—Always Discuss Them with Your Healthcare Provider ...

  15. Instrumentation pour la spectroscopie laser sur faisceau d'ions rapides

    NASA Astrophysics Data System (ADS)

    Bazin, Marc

    Devant l'emergence des technologies exploitant l'infiniment petit, la spectroscopie atomique et moleculaire devient de plus en plus incontournable pour comprendre precisement les mecanismes quantiques impliques dans l'interaction des molecules. C'est le cas notamment de la nanotechnologie, de la dynamique reactionnelle des gaz a effet de serre ou simplement de l'identification des molecules constituant certains objets de l'astrophysique. Bien qu'un travail considerable soit deja accompli pour comprendre la dissociation ou la formation des molecules simples, il reste a vaincre la complexite des mecanismes impliques lorsque les molecules possedent plus de trois noyaux. Parmi les rares techniques de spectroscopie a tres haute resolution (jusqu'a la structure hyperfine), la spectroscopie laser sur faisceaux d'ions rapides est une methode experimentale eprouvee depuis trois decennies environ. Cette methode spectroscopique fournit des resultats comptant parmi les meilleurs pour obtenir des constantes moleculaires precises et permettre la reduction du spectre moleculaire. Une particularite remarquable de notre instrument est la possibilite d'enregistrer le signal de fragmentation moleculaire par laser via les etats de predissociation de la molecule etudiee. Notre contribution a ete d'ameliorer et de moderniser l'equipement existant. Nous avons augmente la resolution spectrale de notre instrument. Nous avons atteint notre principal objectif, a savoir, la possibilite d'acquerir des spectres selon deux modes : par detection du signal synchronisee sur le faisceau laser module en frequence ou par detection du signal directement par comptage. Cette derniere methode est une premiere sur ce type d'instrument et son principal interet a ete d'obtenir une meilleure mesure de l'elargissement de raie. Nous sommes parvenus a mettre clairement en evidence l'elargissement de raie avec la puissance laser en utilisant la methode de detection par comptage direct. La fluorescence induite par

  16. Microplanktonic ATP-Biomass and GTP-Productivity Associated with Upwelling off Pt. Sur, California.

    DTIC Science & Technology

    1980-09-01

    growth potential (based on high AATP/ATP; see below). D . ASSAYING ATP AND GTP The luciferin -luciferase assay principle for ATP [Holm- Hansen and...UPWELLING OFF PT. -SUR, CALIFORNIA. by __Sherman Hughes/Bronsink Thesis Advisor: E. D . Traganza A9 Approved for public release; distribution unlimited...triphosphate (GTP) sampling was found to be high throughout the.. A N 7 1 4 7 3 E T I N O N V 0 5 I O S L S SU N C L A S S I F I E D (Page 1) SNO0*I401SECURITY

  17. Fonction maximale centrée de Hardy-Littlewood sur les espaces hyperboliques

    NASA Astrophysics Data System (ADS)

    Li, Hong-Quan; Lohoué, Noël

    2012-10-01

    On montre que la fonction maximale centrée de Hardy-Littlewood, M, sur les espaces hyperboliques réels {H}n = {R}^{{{raise .17exhbox riptstyle +}{raise .17exhbox riptstyle +}{raise .1exhbox riptscriptstyle +}riptscriptstyle +}} × {R}^{n - 1}, satisfait l'inégalité de type faible \\| M f \\|_{L^{1, infty}} ≤ A (n log {n}) \\| f\\|1 pour toute f∈ L 1(ℍ n ), où A>0 est une constante indépendante de la dimension n.

  18. Discussion Technique: The Twice-Around

    ERIC Educational Resources Information Center

    Andersen, Kent

    2013-01-01

    In this article, the author offers a discussion technique: the twice-around. A variant on the circular response discussion, the twice-around engages students by beginning with students' questions, ensuring equal time for all participants and inviting discussants to build on previous contributions. In the twice-around, participants sit in a circle,…

  19. Leading Discussions: Opening up the Conversation

    ERIC Educational Resources Information Center

    Henning, John E.

    2005-01-01

    Leading a productive discussion, one that both engages students and enhances their understanding, may be the most complex and challenging task in teaching. This article explores three approaches to increasing the productivity of discussions. They include framing discussions in a way that allows students easier access to the topic, making the kind…

  20. Grossesse sur cicatrice de césarienne: à propos d'un cas et revue de la literature

    PubMed Central

    Lachiri, Boutaina; Zazi, Abdelgheni; Benkerroum, Zineb; Hafidi, Moulay Rachid; Kouach, Jaouad; Rahali, Driss Moussaoui; Dehayni, Mohamed

    2015-01-01

    La grossesse sur cicatrice de césarienne est une forme rare de grossesse ectopique qui engage le pronostic vital et fonctionnel utérin par hémorragie ou par rupture utérine précoce. Nous rapportons le cas d'une grossesse ectopique sur cicatrice de césarienne diagnostiquée à 11 semaines d'aménorrhée suite à une aspiration blanche pour grossesse arrêtée chez une patiente de 43 ans porteuse d'un utérus bi-cicatriciel. A travers cette observation ainsi qu'une revue de la littérature les auteurs vont essayer de mettre le point sur les méthodes diagnostiques et thérapeutiques de cette entité rare afin d'améliorer la prise en charge. PMID:26213603

  1. Impacts of Gender Differences on Conducting Operational Activities (Impact des diffrenes homme/femme sur la conduite des activites oprationnelles)

    DTIC Science & Technology

    2008-10-01

    MP-HFM-158 Impacts of Gender Differences on Conducting Operational Activities (Impact des différences homme/ femme sur la conduite des activités...harassment should also be dealt with on a multicultural basis. ES - 2 RTO-MP-HFM-158 Impact des différences homme/ femme sur la...conduite des activités opérationnelles (RTO-MP-HFM-158) Synthèse L’intégration des femmes dans les armées, se fait à un rythme variable dans les

  2. Evaluation des connaissances des parents sur les bronchiolites aiguës

    PubMed Central

    Gueddari, Widad; Tazi, Abderrahmane; Ouardi, Amine; Nani, Samira; Zineddine, Abdelhadi

    2014-01-01

    Les infections respiratoires (IR) constituent la deuxième cause de mortalité infantile au Maroc, dû en partie à l'absence d'information et de sensibilisation. Le but de ce travail était d’évaluer les connaissances des parents sur la bronchiolite aiguë, infection respiratoire très fréquente. Nous avons réalisé une enquête basée sur un questionnaire, auprès de parents de nourrissons consultants pour toux, avec ou sans gêne respiratoire. 180 parents ont été inclus dans l’étude. Les parents pensaient que l'infection respiratoire était secondaire au climat froid (96%); seuls 4% ont évoqué une origine infectieuse. Aucun des parents ne savait que le lavage des mains était un moyen de prévention de la transmission. Les parents ont majoritairement répondu que la kinésithérapie respiratoire ne servait à rien (65%), et qu'elle était nocive (24.5%). Ce manque de connaissances fondamentales en matière d'IR et de bronchiolite en particulier, devrait inciter à entreprendre un programme de sensibilisation PMID:25328606

  3. Adsorption de gaz sur les materiaux microporeux modelisation, thermodynamique et applications

    NASA Astrophysics Data System (ADS)

    Richard, Marc-Andre

    2009-12-01

    Nos travaux sur l'adsorption de gaz dans les materiaux microporeux s'inscrivent dans le cadre des recherches visant a augmenter l'efficacite du stockage de l'hydrogene a bord des vehicules. Notre objectif etait d'etudier la possibilite d'utiliser l'adsorption afin d'ameliorer l'efficacite de la liquefaction de l'hydrogene des systemes a petite echelle. Nous avons egalement evalue les performances d'un systeme de stockage cryogenique de l'hydrogene base sur la physisorption. Comme nous avons affaire a des plages de temperatures particulierement etendues et a de hautes pressions dans la region supercritique du gaz, nous avons du commencer par travailler sur la modelisation et la thermodynamique de l'adsorption. La representation de la quantite de gaz adsorbee en fonction de la temperature et de la pression par un modele semi-empirique est un outil utile pour determiner la masse de gaz adsorbee dans un systeme mais egalement pour calculer les effets thermiques lies a l'adsorption. Nous avons adapte le modele Dubinin-Astakhov (D-A) pour modeliser des isothermes d'adsorption d'hydrogene, d'azote et de methane sur du charbon actif a haute pression et sur une grande plage de temperatures supercritiques en considerant un volume d'adsorption invariant. Avec cinq parametres de regression (incluant le volume d'adsorption Va), le modele que nous avons developpe permet de tres bien representer des isothermes experimentales d'adsorption d'hydrogene (de 30 a 293 K, jusqu'a 6 MPa), d'azote (de 93 a 298 K, jusqu'a 6 MPa) et de methane (de 243 a 333 K, jusqu'a 9 MPa) sur le charbon actif. Nous avons calcule l'energie interne de la phase adsorbee a partir du modele en nous servant de la thermodynamique des solutions sans negliger le volume d'adsorption. Par la suite, nous avons presente les equations de conservation de la niasse et de l'energie pour un systeme d'adsorption et valide notre demarche en comparant des simulations et des tests d'adsorption et de desorption. En plus de l

  4. Volvulus du grêle sur paquet d’ascaris: à propos d’un cas

    PubMed Central

    Diouf, Cheikh; Kane, Ahmed; Ndoye, Ndeye Aby; Ndour, Oumar; Faye-Fall, Aimé Lakh; Fall, Mbaye; Alumeti, Désiré Munyali; Ngom, Gabriel

    2016-01-01

    Nous rapportons un cas exceptionnel de volvulus nécrosé de l'intestin grêle dû à des ascaris adultes chez un enfant de 7 ans. A l'admission, l'enfant présentait le tableau d'occlusion intestinale qui évoluait depuis deux jours avec altération de l'état général. La radiographie de l'abdomen sans préparation retrouvait des niveaux hydroaériques de type grêlique et un aspect tigré évoquant le diagnostic d'une occlusion intestinale haute sur masse abdominale. Après la réanimation, le traitement chirurgical consistait en une laparotomie qui avait retrouvé un volvulus nécrosé de l'iléon terminale contenant des ascaris adultes. Une résection du grêle sur environ un mètre emportant le segment nécrosé suivie d'une iléostomie était réalisée. L'évolution a été favorable, l'anastomose iléo-colique fut réalisée quatre semaines plus tard. Au recul de deux ans l'enfant est indemne de tout symptôme. PMID:27795803

  5. Effet de la composition des materiaux composites sur la caracterisation et detection par ondes de Lamb

    NASA Astrophysics Data System (ADS)

    Ostiguy, Pierre-Claude

    Les matériaux composites sont de plus en plus utilisés en aéronautique. Leurs excellentes propriétés mécaniques et leur faible poids leur procurent un avantage certain par rapport aux matériaux métalliques. Ceux-ci étant soumis à diverses conditions de chargement et environnementales, ils sont suceptibles de subir plusieurs types d'endommagements, compromettant leur intégrité. Des méthodes fiables d'inspection sont donc nécessaires pour évaluer leur intégrité. Néanmoins, peu d'approches non destructives, embarquées et efficaces sont présentement utilisées. Ce travail de recherche se penche sur l'étude de l'effet de la composition des matériaux composites sur la détection et la caractérisation par ondes guidées. L'objectif du projet est de développer une approche de caractérisation mécanique embarquée permettant d'améliorer la performance d'une approche d'imagerie par antenne piézoélectriques sur des structures composite et métalliques. La contribution de ce projet est de proposer une approche embarquée de caractérisation mécanique par ultrasons qui ne requiert pas une mesure sur une multitude d'échantillons et qui est non destructive. Ce mémoire par articles est divisé en quatre parties, dont les parties deux A quatre présentant les articles publiés et soumis. La première partie présente l'état des connaissances dans la matière nécessaires à l'acomplissement de ce projet de maîtrise. Les principaux sujets traités portent sur les matériaux composites, propagation d'ondes, la modélisation des ondes guidées, la caractérisation par ondes guidées et la surveillance embarquée des structures. La deuxième partie présente une étude de l'effet des propriétés mécaniques sur la performance de l'algorithme d'imagerie Excitelet. L'étude est faite sur une structure isotrope. Les résultats ont démontré que l'algorithme est sensible à l'exactitude des propriétés mécaniques utilisées dans le modèle. Cette

  6. Does inhibiting Sur1 complement rt-PA in cerebral ischemia?

    PubMed Central

    Simard, J. Marc; Geng, Zhihua; Silver, Frank L.; Sheth, Kevin N.; Kimberly, W. Taylor; Stern, Barney J.; Colucci, Mario; Gerzanich, Volodymyr

    2012-01-01

    Hemorrhagic transformation (HT) associated with recombinant tissue plasminogen activator (rt-PA) complicates and limits its use in stroke. Here, we provide a focused review on the involvement of matrix metalloproteinase 9 (MMP-9) in rt-PA–associated HT in cerebral ischemia, and we review emerging evidence that the selective inhibitor of the sulfonylurea receptor 1 (Sur1), glibenclamide (U.S. adopted name, glyburide), may provide protection against rt-PA–associated HT in cerebral ischemia. Glyburide inhibits activation of MMP-9, ameliorates edema formation, swelling, and symptomatic hemorrhagic transformation, and improves preclinical outcomes in several clinically relevant models of stroke, both without and with rt-PA treatment. A retrospective clinical study comparing outcomes in diabetic patients with stroke treated with rt-PA showed that those who were previously on and were maintained on a sulfonylurea fared significantly better than those whose diabetes was managed without sulfonylureas. Inhibition of Sur1 with injectable glyburide holds promise for ameliorating rt-PA–associated HT in stroke. PMID:22994227

  7. Visual Analysis and Dissemination of Scientific Literature Collections with SurVis.

    PubMed

    Beck, Fabian; Koch, Sebastian; Weiskopf, Daniel

    2016-01-01

    Bibliographic data such as collections of scientific articles and citation networks have been studied extensively in information visualization and visual analytics research. Powerful systems have been built to support various types of bibliographic analysis, but they require some training and cannot be used to disseminate the insights gained. In contrast, we focused on developing a more accessible visual analytics system, called SurVis, that is ready to disseminate a carefully surveyed literature collection. The authors of a survey may use our Web-based system to structure and analyze their literature database. Later, readers of the survey can obtain an overview, quickly retrieve specific publications, and reproduce or extend the original bibliographic analysis. Our system employs a set of selectors that enable users to filter and browse the literature collection as well as to control interactive visualizations. The versatile selector concept includes selectors for textual search, filtering by keywords and meta-information, selection and clustering of similar publications, and following citation links. Agreement to the selector is represented by word-sized sparkline visualizations seamlessly integrated into the user interface. Based on an analysis of the analytical reasoning process, we derived requirements for the system. We developed the system in a formative way involving other researchers writing literature surveys. A questionnaire study with 14 visual analytics experts confirms that SurVis meets the initially formulated requirements.

  8. Modifications vibrationnelles induites par différentes vapeurs acides sur les polyanilines

    NASA Astrophysics Data System (ADS)

    Cochet, M.; Quillard, S.; Buisson, J. P.; Lefrant, S.; Louarn, G.

    1998-06-01

    We present a comparative study of conductive form of polyaniline, i.e, polyemeraldine doped with HCl vapor or with HCSA upon m-cresol vapor. UV-Vis.-nir absorption measurements on polyaniline thin films, vs acid vapors time exposure, have been made. In the same way, Raman spectra have been recorded with different excitation lines from the blue and red ranges to the infrared region. Finally, an assignment of Raman bands observed, is proposed and confirmed by vibrational calculations based on valence-force-field. Nous présentons une étude comparative de la forme conductrice de la polyaniline, c'est-à-dire de la polyéméraldine dopée par des vapeurs d'HCl ou dopée par l'acide camphre sulfonique (HCSA) sous vapeurs de m-crésol. Des mesures d'absorption UV-Vis-proche infrarouge sur des films minces de polyaniline, en fonction du temps d'exposition aux vapeurs acides, ont été réalisées. Parallèlement, les spectres Raman ont été obtenus pour différentes longueurs d'onde d'excitation allant du visible jusqu'au proche infrarouge. Finalement, une attribution des bandes Raman observées est proposée et confirmée par des calculs vibrationnels basés sur des champs de force de valence.

  9. Cancer du sein sur tissu mammaire ectopique: à propos de 2 cas

    PubMed Central

    Haddad, Houssam; Bourhaleb, Zouhour; El Harroudi, Tijani; Mezouar, Loubna; El Hfid, Mohamed

    2012-01-01

    Le cancer du sein sur tissu mammaire ectopique est une tumeur rare qui représente 0,2 à 0,6% de l′ensemble des cancers du sein. Les auteurs en rapportent 2 cas pris en charge dans 2 centres d′oncologie marocains. Il s′agit de 2 patientes âgées de 31 ans et 47 ans présentant un cancer du sein sur tissu mammaire ectopique en situation axillaire. Une tumorectomie avec curage ganglionnaire axillaire homolatéral a été réalisée chez les 2 patientes dont une après une chimiothérapie néoadjuvante. Le traitement adjuvant a compris une chimiothérapie, radiothérapie puis une hormonothérapie. Après un recul de 12 mois et 20 mois respectivement, les 2 patientes sont en rémission complète. PMID:23330041

  10. Compactification de la Supergravite 10-D Sur les Varietes de Calabi-Yau

    NASA Astrophysics Data System (ADS)

    Gagnon, Michel

    Les varietes de Calabi-Yau permettent une description relativement simple et assez juste de la realite. Recemment, de nombreuses equipes de recherche s'y sont interessees, en particulier P. Candelas, A. M. Dale, C. A. Lutken et R. Schimmrigk (13) qui ont propose une liste de 7868 configurations distinctes. Toutefois, nous croyons que certaines des techniques qui sont exploitees pour construire cette liste ne sont pas suffisamment justifiees et ont pour effet de soustraire a nos investigations bon nombre de configurations potentiellement interessantes. Ainsi, nous produisons, sans utiliser ces techniques simplificatrices, une liste de 97360 configurations. Ensuite, dans le cadre des modeles a 4 generations, nous appliquons un ensemble de criteres, fondes sur les symetries discretes, pour delimiter le domaine des configurations phenomenologiquement viables. Finalement, apres avoir fixe notre choix sur une configuration particuliere, nous essayons de montrer tout l'interet physique des varietes de Calabi-Yau en exposant certains aspects de la phenomenologie a basse energie, notamment les nombres quantiques, les spectres fermioniques, la brisure intermediaire du groupe de jauge et la duree de vie du proton.

  11. Les enjuex éthiques entourant la recherche en santé sur les enfants

    PubMed Central

    2008-01-01

    RÉSUMÉ La recherche en santé est un devoir moral parce qu’elle est la base des soins probants prodigués par tous les dispensateurs de soins. Des politiques et des règlements précis régissent la tenue des recherches sur des humains. Il faut procéder à une évaluation éthique d’un projet de recherche donné avant de pouvoir l’entreprendre. La recherche sur les enfants pose d’énormes défis en matière de consentement éclairé et d’assentiment, de vulnérabilité et de potentiel de conflit d’intérêts (CDI). Les chercheurs en santé pédiatrique devraient prôner la participation des enfants à la recherche, tout en se montrant attentifs à en limiter les risques.

  12. Implementation of tsunami disaster prevention measures in the municipality of San Rafael del Sur, Nicaragua

    NASA Astrophysics Data System (ADS)

    Strauch, W.; Talavera, E.; Acosta, N.; Sanchez, M.; Mejia, E.

    2007-05-01

    The Nicaraguan Pacific coast presents considerable tsunami risk. On September 1, 1992, a tsunami caused enormous damage in the infrastructure and killed more than 170 people. A pilot project was conducted between 2006 and 2007 in the municipality of San Rafel del Sur, area of Masachapa, The project included multiple topics of tsunami prevention measures and considering the direct participation of the local population, as: -General education on disaster prevention, participative events; -Investigation of awareness level and information needs for different population groups; -Specific educational measures in the schools; -Publication of brochures, calendars, news paper articles, radio programs, TV spots -Development of local tsunami hazard maps, 1:5,000 scale; (based on previous regional tsunami hazard mapping projects and local participation) -Development of a tsunami warning plan; -Improvements of the national tsunami warning system. -Installation of sirens for tsunami warning -Installation of tsunami signs, indicating hazardous areas, evacuation routes, safe places; -Realization of evacuation drills in schools. Based on the experiences gained in Masachapa it is planned to run similar projects in other areas along the Nicaraguan Pacific coast. In the project participated the local municipality and local stakeholders of San Rafael del Sur, Ministry of Education, National Police, Nicaraguan Red Cross, Ministry of Health, Ministry of Tourism, Nicaraguan Geosciences Institute (INETER), National System for Disaster Prevention (SINAPRED), Swiss Agency for Development and Cooperation (SDC). It was financed by SDC and INETER.

  13. Describing the Elephant: Framing a Discussion on Command and Control

    DTIC Science & Technology

    2014-08-01

    operations in support of combat- ant commanders. A master navigator with more than 4,200 flying hours, pri- marily in the RC-135 Rivet Joint and E-8C JSTARS...that term varies across the levels of war; by service, mediums, career fields, and platforms; and across the realms of academics, joint -requirements...the battlespace. Although designed to be platform agnostic, most of the articles incorporate recent experience with the Joint Sur- veillance Target

  14. Intertextuality in Text-Based Discussions

    ERIC Educational Resources Information Center

    Ismail, Hamidah Mohd; Majid, Faizah Abd

    2011-01-01

    One of the main issues often discussed among academics is how to encourage active participation by students during classroom discussions. This applies particularly to students at the tertiary level who are expected to possess creative and critical thinking skills. Hence, this paper reports on a study that examined how these skills were…

  15. Interteaching: Discussion Group Size and Course Performance

    ERIC Educational Resources Information Center

    Truelove, Jacob C.; Saville, Bryan K.; Van Patten, Ryan

    2013-01-01

    Researchers have yet to examine whether discussion group size affects student performance in an interteaching-based course. In the current study, we addressed this question by manipulating discussion group size (smaller groups of 2 students vs. larger groups of 4 students) across 2 sections of an undergraduate psychology course. We found no…

  16. Building Fires: Raising Achievement through Class Discussion

    ERIC Educational Resources Information Center

    Kahn, Elizabeth

    2007-01-01

    According to a growing body of research, discussion-based instruction, in the context of high academic demands, significantly enhances student achievement in reading. The effects apply to below- as well as above-average-ability students. These findings confirm what secondary English teachers have believed all along about the value of discussion.…

  17. Building Knowledge and Community through Online Discussion

    ERIC Educational Resources Information Center

    Skinner, Elisabeth

    2007-01-01

    A web conference "adds value by generating discussion among a diverse student group" (Skinner, 2004a, p. 12). Or does it? A significant concern is the extent to which learners construct knowledge and develop a learning community through online discussion. Critics argue that genuine knowledge construction is difficult to achieve. This study…

  18. Preparing Teachers to Lead Mathematics Discussions

    ERIC Educational Resources Information Center

    Boerst, Timothy A.; Sleep, Laurie; Ball, Deborah Loewenberg; Bass, Hyman

    2011-01-01

    Background/Context: Discussion is central to mathematics teaching and learning, as well as to mathematics as an academic discipline. Studies have shown that facilitating discussions is complex work that is not easily done or learned. To make such complex aspects of the work of teaching learnable by beginners, recent research has focused on…

  19. Improving Classroom Discussion: A Rhetorical Approach

    ERIC Educational Resources Information Center

    Bruss, Kristine S.

    2009-01-01

    In this article, the author describes a project designed to take the dread out of discussion in a first-year interdisciplinary humanities course at Sewanee: The University of the South, a private liberal arts college in Tennessee. The Responsible Intellectual Discussion project, known as RID, was created in conjunction with the college's Eloquence…

  20. Finding Malicious Cyber Discussions in Social Media

    DTIC Science & Technology

    2015-12-11

    attacker techniques and tools, and potential victims. Applying modern machine learning approaches, Lincoln Laboratory has demonstrated the ability to...are not necessarily endorsed by the United States Government. 2 discussion text via machine learning and human language technology (HLT...machine learning classifier to determine if a discussion concerns malicious cyber topics: 1. An analyst has already discovered Internet content, such

  1. Engaging All Students in Mathematical Discussions

    ERIC Educational Resources Information Center

    Bahr, Damon L.; Bahr, Kim

    2017-01-01

    Many teachers try to engage their students in meaningful mathematical discussions in which one or more students share their thinking about a problem while the other students are expected to listen and learn from the sharing. Indeed, such discussions can help students learn from one another and promote high levels of mathematical proficiency.…

  2. Comparing Tasks and Skills in Developing Discussions.

    ERIC Educational Resources Information Center

    Robinson, Peter; Strong, Gregory; Whittle, Jennifer

    Developing the skills necessary to participate in academic discussions is an important goal in many programs of English for academic purposes. However, there has been little empirical investigation into how verbal and nonverbal aspects of discussion abilities might be developed. This paper reports the results of a semester-long effect of…

  3. Integrating Online Discussion: Broadening the Conversation

    ERIC Educational Resources Information Center

    Li, Qing

    2006-01-01

    This article shares an approach to teaching mathematics teacher education courses incorporating asynchronous online discussions. Specifically, this research is guided by the following research questions: (a) How would online discussions contribute or hinder teachers' learning in mathematics methods courses? and (b) What pedagogical strategies need…

  4. Enhancing Understanding and Interest through Group Discussion

    ERIC Educational Resources Information Center

    Cannon, Patrick

    2006-01-01

    Group discussion allows students to learn how to "talk to someone." Through group discussion, students can acquire or refine a broad range of attributes, from basic oratory skills to a more sophisticated development of communicative competence to embracing and valuing dialogic interchange and reflexivity. In this article, the author explains how…

  5. Learning Reading Strategies with Online Discussion

    ERIC Educational Resources Information Center

    Liu, I-Fang; Ko, Hwa-Wei; Wu, Sheng-Yi

    2014-01-01

    Teachers experience difficulty demonstrating prediction strategies and leading discussions in traditional classrooms. It is also unclear whether online discussion can contribute to reading comprehension. The purpose of this study is to create an online reading system to investigate whether learners can acquire reading strategies and enhance their…

  6. Building Fires: Raising Achievement through Class Discussion

    ERIC Educational Resources Information Center

    Kahn, Elizabeth

    2007-01-01

    According to a growing body of research, discussion-based instruction, in the context of high academic demands, significantly enhances student achievement in reading. The effects apply to below- as well as above-average-ability students. These findings confirm what secondary English teachers have believed all along about the value of discussion.…

  7. Managing the Paradoxes of Discussion Pedagogy

    ERIC Educational Resources Information Center

    Piro, Jody S.; Anderson, Gina

    2015-01-01

    Discussion pedagogy is part of a larger curricular goal that intersects the two aspirations of diversity of perspectives and democratic inquiry in that it challenges stereotypes and assumptions through student discourse. Yet, teaching with discussion is a complex and sometimes ambiguous endeavor that leaves instructors feeling pulled between…

  8. Encouraging Critical Thinking through Expert Panel Discussions

    ERIC Educational Resources Information Center

    Bucy, Mary C.

    2006-01-01

    Encouraging critical thinking in classroom discussions when the class consists of students with similar backgrounds and professional experience can be challenging. This article reports on one method for introducing multiple viewpoints into discussions by requiring students to represent views from well-known personalities who are vocal in current…

  9. Accounting for Outcomes in Case Discussions.

    ERIC Educational Resources Information Center

    Corrigan, Stephanie Zweig; Morine-Dershimer, Greta

    This study analyzes the reaction essays of 24 elementary preservice teachers who read and discussed the same case. The preservice teachers were in two different sections of the same special topics course. Care was taken to balance the sections as closely as possible by age, ethnicity, and major areas. Graduate discussion leaders were chosen to…

  10. Exploring Discipline Differentiation in Online Discussion Participation

    ERIC Educational Resources Information Center

    Redmond, Petrea; Devine, Jo; Basson, Marita

    2014-01-01

    Online discussion forums are often the only interaction or communication a student in an online learning environment will have with the course instructor and fellow students. Discussion forums are intended to elicit a range of thinking skills from the students, from purely social interaction to metacognition in order to achieve deep learning.…

  11. The Three E's of Online Discussion

    ERIC Educational Resources Information Center

    Dixon, Carmen S.

    2014-01-01

    Online discussion is becoming more widespread as online classes move to the forefront of education. However, information for teachers about effective use of the online method of instruction is not readily available. This article identifies three models of discussion, extracts the elements from those models that will work well online, and combines…

  12. Discussion-Based Instruction in Drug Metabolism.

    ERIC Educational Resources Information Center

    Ruenitz, Peter C.

    1995-01-01

    A flexible strategy for large-group pharmacy instruction in drug metabolism has students prepare and discuss answers to fact-oriented study questions, addressing fundamentals covered in a textbook, with regular evaluation of in-class student responses to higher-order review questions. This discussion-based approach has brought sustained…

  13. Public Energy Education: Issues for Discussion. Draft.

    ERIC Educational Resources Information Center

    Public Energy Education Task Force.

    This paper was intended to stimulate discussion of energy education issues at a conference on energy issues. The discussion ranges through numerous topics at issue in energy education including public energy awareness, definition of public education, the distinction between public education and public relations, and the presentation of a model…

  14. Discussion Starters. Technical Note No. 25.

    ERIC Educational Resources Information Center

    Yunus, Ibrahim; Dilts, Russ

    Discussion starters, the result of collaboration between the Indonesian Directorate General of Nonformal Education, Youth, and Sports, and World Education, Inc., are simple learning tools used to generate discussion among community groups involved in nonformal education. Appropriate in and adaptable to a variety of settings, content areas, and…

  15. Discussion Guide for Film: "Teams for Learning."

    ERIC Educational Resources Information Center

    Bowman, Garda W.; Galinsky, Ellen

    This discussion guide was prepared to accompany a 26 1/2-minute, black and white 16 mm. film, "Teams for Learning," which portrays teams of teachers and auxiliary personnel in action in four types of schools. A brief outline of the film, the purpose of which is to stimulate discussion and behavior analysis among team members during their training,…

  16. Assessing Student Contributions to Online Discussion Boards

    ERIC Educational Resources Information Center

    Smith, Helen

    2008-01-01

    The use of online learning is prevalent in higher education, in particular the use of Blackboard and other similar virtual learning environments (VLEs). Students' participation in online discussion forums is a common activity and the online threaded discussion tool provides opportunities for students to: (1) form collaborative groups for…

  17. Group Discussion as Learning Process. A Sourcebook.

    ERIC Educational Resources Information Center

    Flynn, Elizabeth W.; La Faso, John F.

    Designed to be of practical assistance to those interested in improving their abilities for group discussion leadership and participation and their knowledge of learning-discussion groups, this book is organized so that the first seven chapters are concerned with theory and the last seven concern practical application. The chapter titles are as…

  18. A Workbook for Training Discussion Leaders.

    ERIC Educational Resources Information Center

    Menkin, Paula

    This guide on group discussion leader training provides for a four session course structured to enable each trainee to practice and be evaluated. Session 1 stresses the nature and uses of discussion, and introduces trainees to role playing. Other sessions concentrate on summarizing and decision making; on group satisfaction or problem solving and…

  19. The Adventure of the Discussion Board.

    ERIC Educational Resources Information Center

    Davis, Don

    This paper describes the frustration with the lack student involvement in classroom discussions regarding significant issues of the California State History Social Science Standards, specifically on politics and media. The initial use of a discussion board produced disappointing results. Very few students participated and their responses did not…

  20. Online Discussion, Student Engagement, and Critical Thinking

    ERIC Educational Resources Information Center

    Williams, Leonard; Lahman, Mary

    2011-01-01

    Recent research into the merits of online discussion (computer-mediated communication) has shown that it promotes active learning behaviors and enhances learner outcomes. Scholars have also shown that, when instructors employ effective questioning and moderating skills, students can show higher levels of critical thinking in online discussion. In…

  1. Learning Reading Strategies with Online Discussion

    ERIC Educational Resources Information Center

    Liu, I-Fang; Ko, Hwa-Wei; Wu, Sheng-Yi

    2014-01-01

    Teachers experience difficulty demonstrating prediction strategies and leading discussions in traditional classrooms. It is also unclear whether online discussion can contribute to reading comprehension. The purpose of this study is to create an online reading system to investigate whether learners can acquire reading strategies and enhance their…

  2. Enhancing Understanding and Interest through Group Discussion

    ERIC Educational Resources Information Center

    Cannon, Patrick

    2006-01-01

    Group discussion allows students to learn how to "talk to someone." Through group discussion, students can acquire or refine a broad range of attributes, from basic oratory skills to a more sophisticated development of communicative competence to embracing and valuing dialogic interchange and reflexivity. In this article, the author explains how…

  3. Global Leadership Competencies: A Review and Discussion

    ERIC Educational Resources Information Center

    Jokinen, Tiina

    2005-01-01

    Purpose: From the competency point of view, this article aims to review and discuss existing global leadership and other related literature, and to combine findings and suggestions provided in previous literature in a more integrative framework of global leadership competencies. Design/methodology/approach: The paper reviews and discusses the…

  4. Group Discussions with the Emotionally Handicapped.

    ERIC Educational Resources Information Center

    Pepper, Floy Childers; Roberson, Mickey

    The paper discusses the use of regularly scheduled classroom group discussions in the treatment of emotionally disturbed (ED) children, to assist them in learning alternative ways of acting and interacting and to move them from feelings of discouragement and negativism to the point where they can effect change in themselves, feel confident in…

  5. Public Energy Education: Issues for Discussion. Draft.

    ERIC Educational Resources Information Center

    Public Energy Education Task Force.

    This paper was intended to stimulate discussion of energy education issues at a conference on energy issues. The discussion ranges through numerous topics at issue in energy education including public energy awareness, definition of public education, the distinction between public education and public relations, and the presentation of a model…

  6. Preparing Teachers to Lead Mathematics Discussions

    ERIC Educational Resources Information Center

    Boerst, Timothy A.; Sleep, Laurie; Ball, Deborah Loewenberg; Bass, Hyman

    2011-01-01

    Background/Context: Discussion is central to mathematics teaching and learning, as well as to mathematics as an academic discipline. Studies have shown that facilitating discussions is complex work that is not easily done or learned. To make such complex aspects of the work of teaching learnable by beginners, recent research has focused on…

  7. National GAP Conference 2007-Discussion Groups Report

    USGS Publications Warehouse

    Ratz, Joan M.; Lamb, Berton Lee

    2010-01-01

    We led two discussion groups during the 2007 National GAP Conference. These discussion groups provided information to help develop a survey of National Gap Analysis Program (GAP) data users. One group discussed technical issues, and the second group discussed the use of GAP data for decisionmaking. Themes emerging from the technical issues group included concerns about data quality, need for information on how to use data, and passive data distribution. The decisionmaking discussion included a wide range of topics including the need to understand presentation of information, the need to connect with and understand users of data, the revision of GAP's mission, and the adaptability of products and data. The decisionmaking group also raised concerns regarding technical issues. One conclusion is that a deep commitment to ongoing information transfer and support is a key component of success for the GAP program.

  8. Discussion Forum for Technical Codes Users

    SciTech Connect

    Kaspar, Bryce P.; Dillon, Heather E.

    2006-03-30

    One goal of the Building Energy Codes Program (BECP) is to provide useful, easy to understand information about the national energy codes. A forum where users could ask for, and receive clarification on these codes and software from other users would allow the Energy codes project to reach and instruct a broader audience for a modest resource cost. The forum proposed would be a staff moderated discussion board where staff would post topics, and users would post discussion of those topics, with staff joining in to the discussions. The forum would be moderated by staff members, to remove objectionable and irrelevant postings, and to answer any technical questions that arise. The topics and discussions would be archived and searchable to allow users to answer their own questions, if they pertain to a previously discussed topic.

  9. Prevalence of infection with Toxoplasma gondii in landrace and mixed breed pigs slaughtered in Baja California Sur state, Mexico

    USDA-ARS?s Scientific Manuscript database

    Purpose We performed a cross-sectional study to determine the seroprevalence of Toxoplasma gondii infection in 308 domestic pigs slaughtered in La Paz, Baja California Sur State, Mexico using the modified agglutination test (MAT, cut off 1:25). Results Forty (13%) of the 308 pigs were seropositive ...

  10. SurA Is Involved in the Targeting to the Outer Membrane of a Tat Signal Sequence-Anchored Protein

    PubMed Central

    Rondelet, Arnaud

    2012-01-01

    The twin arginine translocation (Tat) pathway exports folded proteins from the cytoplasm to the periplasm of bacteria. The targeting of the exported proteins to the Tat pathway relies on a specific amino-terminal signal sequence, which is cleaved after exportation. In the phytopathogen Dickeya dadantii, the pectin lyase homologue PnlH is exported by the Tat pathway without cleavage of its signal sequence, which anchors PnlH into the outer membrane. In proteobacteria, the vast majority of outer membrane proteins consists of β-barrel proteins and lipoproteins. Thus, PnlH represents a new kind of outer membrane protein. In Escherichia coli, periplasmic chaperones SurA, Skp, and DegP work together with the β-barrel assembly machinery (Bam) to target and insert β-barrel proteins into the outer membrane. In this work, we showed that SurA is required for an efficient targeting of PnlH to the outer membrane. Moreover, we were able to detect an in vitro interaction between SurA and the PnlH signal sequence. Since the PnlH signal sequence contains a highly hydrophobic region, we propose that SurA protects it from the hydrophobic periplasm during targeting of PnlH to the outer membrane. We also studied the nature of the information carried by the PnlH signal sequence responsible for its targeting to the outer membrane after exportation by the Tat system. PMID:22961852

  11. Lignes directrices pour le suivi des cardiostimulateurs au canada : consensus du groupe de travail canadien sur la cardiostimulation

    PubMed

    D Fraser JD; M Gillis AM; Irwin; Nishimura; Tyers; Philippon

    2000-03-01

    Un sondage sur les pratiques de cardiostimulation au Canada effectue en 1997 a revele un profond desir pour des lignes directrices nationales sur le suivi des cardiostimulateurs. Ces lignes directrices sur le suivi des cardiostimulateurs representent une declaration de consensus du Groupe de travail canadien sur la cardiostimulation. Le suivi des patients en personne plutot que par moyens transtelephoniques est preferable. Les patients devraient etre examines au minimum dans les 72 heures suivant l'implantation, 2 a 12 semaines et 6 mois apres l'implantation, et annuellement par la suite. Des examens plus frequents peuvent etre requis pour certains patients. Ceci dependra des problemes cardiovasculaires associes et des appareils en particulier. Une visite de suivi typique devrait comprendre un examen cardiovasculaire oriente, l'interrogation du systeme de cardiostimulation et une revue des donnees de telemetrie, un examen du rythme sous-jacent, un examen des seuils de stimulation et de detection et une reprogrammation adequate des parametres pour optimaliser le fonctionnement et la longevite de l'appareil.

  12. Endocardite infectieuse sur communication interventriculaire: intérêt de l’échocardiographie? de l’antibioprophylaxie?

    PubMed Central

    Boussir, Hanane; Ghalem, Amine; Ismaili, Nabila; El Ouafi, Noha

    2016-01-01

    L’endocardite infectieuse peut survenir sur un cœur sain ou pathologique. Parmi les cardiopathies à risque, on trouve les cardiopathies congénitales dont la CIV est la plus fréquente. Nous rapportons le cas d’une endocardite infectieuse à streptocoque oral, survenue sur une CIV non connue jusqu’à maintenant, chez un patient de 17 ans, se présentant sous forme de fièvre prolongée associée à une éruption cutanée. L’examen de la sphère ORL révéla par ailleurs des angines pseudomembraneuses avec un mauvais état buccodentaire. Les EI sur CIV sont les plus fréquentes des EI sur cardiopathie congénitale. Leur présentation clinique peut être atypique d’où le rôle primordial de l’échocardiographie. La prévention dans ces cas passe par une hygiène bucco-dentaire et cutanée optimale et non par une antibioprophylaxie. PMID:28292116

  13. A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1

    PubMed Central

    Shimomura, Kenju; Tusa, Maija; Iberl, Michaela; Brereton, Melissa F.; Kaizik, Stephan; Proks, Peter; Lahmann, Carolina; Yaluri, Nagendra; Modi, Shalem; Huopio, Hanna; Ustinov, Jarkko; Otonkoski, Timo; Laakso, Markku; Ashcroft, Frances M.

    2013-01-01

    Loss-of-function mutations in the KATP channel genes KCNJ11 and ABCC8 cause neonatal hyperinsulinism in humans. Dominantly inherited mutations cause less severe disease, which may progress to glucose intolerance and diabetes in later life (e.g., SUR1-E1506K). We generated a mouse expressing SUR1-E1506K in place of SUR1. KATP channel inhibition by MgATP was enhanced in both homozygous (homE1506K) and heterozygous (hetE1506K) mutant mice, due to impaired channel activation by MgADP. As a consequence, mutant β-cells showed less on-cell KATP channel activity and fired action potentials in glucose-free solution. HomE1506K mice exhibited enhanced insulin secretion and lower fasting blood glucose within 8 weeks of birth, but reduced insulin secretion and impaired glucose tolerance at 6 months of age. These changes correlated with a lower insulin content; unlike wild-type or hetE1506K mice, insulin content did not increase with age in homE1506K mice. There was no difference in the number and size of islets or β-cells in the three types of mice, or evidence of β-cell proliferation. We conclude that the gradual development of glucose intolerance in patients with the SUR1-E1506K mutation might, as in the mouse model, result from impaired insulin secretion due a failure of insulin content to increase with age. PMID:23903354

  14. Effets de la pollution de l’air sur la santé

    PubMed Central

    Abelsohn, Alan; Stieb, Dave M.

    2011-01-01

    Résumé Objectif Faire connaître aux médecins de famille les effets de la pollution atmosphérique sur la santé et indiquer quels conseils donner aux patients vulnérables pour qu’ils soient moins exposés. Sources de l’information On a consulté MEDLINE à l’aide des termes relatifs à la pollution atmosphérique et à ses effets indésirables. On a révisé les articles en anglais publiés entre janvier 2008 et décembre 2009. La plupart des études contenaient des preuves de niveau II. Principal message Au Canada, la pollution de l’air extérieur cause une morbidité et une mortalité importantes. Elle peut affecter le système respiratoire (exacerbation de l’asthme et de la maladie pulmonaire obstructive chronique) et le système cardiovasculaire (déclencher l’arythmie, l’insuffisance cardiaque et les AVC). La cote air santé (CAS) est un nouvel outil de communication mis au point par Santé Canada et Environnement Canada qui indique sur une échelle de 1 à 10, le risque pour la santé causé par la pollution atmosphérique. La CAS est largement diffusée dans les médias et cet outil pourrait être utile au médecin de famille pour inciter les patients à haut risque (comme ceux qui souffrent d’asthme, de maladie pulmonaire obstructive chronique ou d’insuffisance cardiaque) à réduire leur exposition à la pollution atmosphérique. Conclusion Le médecin de famille peut se servir de la CAS et de ses messages sur la santé pour enseigner aux asthmatiques et aux autres patients à risque élevé la façon de réduire les risques pour la santé causés par la pollution atmosphérique.

  15. Otoacoustic Emissions (Part II): A moderated discussion

    NASA Astrophysics Data System (ADS)

    Köppl, Christine

    2015-12-01

    The following is an edited transcript of a recorded discussion session on the topic of "Otoacoustic Emissions". The discussion, moderated by the author, took place at the 12th International Workshop on the Mechanics of Hearing held at Cape Sounio, Greece, in June 2014. All participants knew that the session was being recorded. In view of both the spontaneous nature of the discussion and the editing, however, this transcript may not represent the considered or final views of the participants, and may not represent a consensus of experts in the field. The reader is advised to consult additional independent publications.

  16. Cochlear Micromechanics (Part I): A moderated discussion

    NASA Astrophysics Data System (ADS)

    Neely, Stephen T.

    2015-12-01

    The following is an edited transcript of a recorded discussion session on the topic of "Cochlear Micromechanics". The discussion, moderated by the author, took place at the 12th International Workshop on the Mechanics of Hearing held at Cape Sounio, Greece, in June 2014. All participants knew that the session was being recorded. In view of both the spontaneous nature of the discussion and the editing, however, this transcript may not represent the considered or final views of the participants, and may not represent a consensus of experts in the field. The reader is advised to consult additional independent publications.

  17. Cochlear Micromechanics (Part II): A moderated discussion

    NASA Astrophysics Data System (ADS)

    Gummer, Anthony W.; Mountain, David C.

    2015-12-01

    The following is an edited transcript of a recorded discussion session on the topic of "Cochlear Micromechanics". The discussion, moderated by the authors, took place at the 12th International Workshop on the Mechanics of Hearing held at Cape Sounio, Greece, in June 2014. All participants knew that the session was being recorded. In view of both the spontaneous nature of the discussion and the editing, however, this transcript may not represent the considered or final views of the participants, and may not represent a consensus of experts in the field. The reader is advised to consult additional independent publications.

  18. Joint Discussion 14 Modeling dense stellar systems

    NASA Astrophysics Data System (ADS)

    Sills, Alison I.; Subr, Ladislav; Portegies Zwart, Simon F.

    2007-08-01

    Joint Discussion 14 was held at the General Assembly of the International Astronomical Union from August 17 until 23 in the beautiful Bohemian capital, Prague. The blueprints for this meeting were laid out during the MODEST-5 workshop, held in the Canadian city of Hamilton, Ontario in August 2004. We were sitting in a nice cafe with local brew and food, discussing the future of the MODEST community when we posed the idea for this Joint Discussion at the General Assembly. The meeting was then coined MODEST-7.

  19. Complications of Poly Implant Prothèse breast implants: the current discussion.

    PubMed

    Kolios, Leila; Hirche, Christoph; Spiethoff, Alexander; Daigeler, Adrien; Lehnhardt, Marcus

    2013-03-01

    Against the background of the current discussion about Poly Implant Prothèse (PIP, Seyne-sur-mer, France) breast implants, we want to present a case demonstrating the complications such as implant rupture, silicone dissemination and level III silicone lymphadenopathy. A 29-year-old woman with cosmetic breast augmentation with PIP implants 5 years previously showed a sensitive swelling in her right axilla and neck region. All tests to detect an infectious or lymphomatous lymphadenopathy were negative. After ultrasound and MRI, rupture of the right implant was assumed and multiple pathologically enlarged lymph nodes up to supraclavicular region were shown. An excision biopsy of one axillary lymph node was performed; the histological examination detected a strong silicone lymphadenopathy. Surgical removal of both implants as well as capsulectomy was performed and 14 axillary lymph nodes up to level II were resected. Histologic evaluation confirmed the previous results. Our case underlines the actual discussion concerning increased rupture rate and massive silicone lymphadenopathy by PIP implants. The Agence Francaise de Sécurité Sanitaire des Produits de Santé (AFSSAPS) recommends clinical and ultrasound examination every 6 months for women with PIP implants. Any rupture, suspected rupture or leakage of prosthesis should lead to its explantation as well as that of the contralateral implant. In cases of unusual signs of inflammation, histological and immunohistochemical samples are to be taken.

  20. Late Cardiac Events after Childhood Cancer: Methodological Aspects of the Pan-European Study PanCareSurFup

    PubMed Central

    Feijen, Elizabeth A. M.; Font-Gonzalez, Anna; van Dalen, Elvira C.; van der Pal, Helena J. H.; Reulen, Raoul C.; Winter, David L.; Kuehni, Claudia E.; Haupt, Riccardo; Alessi, Daniela; Byrne, Julianne; Bardi, Edit; Jakab, Zsuzsanna; Grabow, Desiree; Garwicz, Stanislaw; Jankovic, Momcilo; Levitt, Gill A.; Skinner, Roderick; Zadravec Zaletel, Lorna; Hjorth, Lars; Tissing, Wim J. E.; de Vathaire, Florent; Hawkins, Mike M.; Kremer, Leontien C. M.

    2016-01-01

    Background and Aim Childhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup. Methods Eight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors. Data on symptomatic heart failure, ischemia, pericarditis, valvular disease and arrhythmia were collected and graded according to the Criteria for Adverse Events. Detailed treatment data, data on potential confounders, lifestyle related risk factors and general health problems were collected. Results The PanCareSurFup cardiac cohort consisted of 59,915 5-year childhood cancer survivors with malignancies diagnosed between 1940 and 2009 and classified according to the International Classification of Childhood Cancer 3. Different strategies were used to identify cardiac events such as record linkage to population/ hospital or regional based databases, and patient- and general practitioner-based questionnaires. Conclusion The cardiac study of the European collaborative research project PanCareSurFup will provide the largest cohort of 5-year childhood cancer survivors with systematically ascertained and validated data on symptomatic cardiac events. The result of this study can provide information to minimize the burden of cardiac events in childhood cancer survivors by tailoring the follow-up of childhood cancer survivors at high risk of cardiac adverse events, transferring this knowledge into evidence-based clinical practice guidelines and providing a platform for future research studies in childhood cancer patients.  PMID:27643694

  1. Ophthalmic Combination of SurR9-C84A and Trichostatin-A Targeting Molecular Pathogenesis of Alkali Burn

    PubMed Central

    Roy, Kislay; Sriramoju, Bhasker; Kanwar, Rupinder K.; Kanwar, Jagat R.

    2016-01-01

    Background: Alkali burn is a frequently occurring ocular injury that resembles ocular inflammation caused by eye allergies, infection, and refractive surgeries. Methods: We investigated the synergistic regenerative potential of dominant negative survivin mutant (SurR9-C84A) and histone deacetylase (HDAC) inhibitor trichostatin-A (TSA) against alkali burn and corneal haze using human keratocytes and rabbit alkali burn model (Female New Zealand white rabbits). Results: Combination of SurR9-C84A and TSA suppressed levels of transforming growth factor (TGF)-β, alpha smooth-muscle actin (α-SMA), fibronectin and HDAC1, leading to apoptosis in myofibroblast cells and, showed the potential to clear the corneal haze. An insult with 0.5 N NaOH for 1 min led to neutrophils infiltration and formation of large vacuoles in the stroma. Treatments with TSA and SurR9-C84A for 40 min led to improvement in the conjunctival and corneal tissue integrity, marked by an increase in clathrin, and claudin expressions. An increase in TGF-β and endogenous survivin confirmed wound healing and cell proliferation in rabbit cornea. The blood analysis revealed a substantial decrease in the RBC, WBC, platelets, or the hemoglobin content post alkali burn. The cytokine array analysis revealed that NaOH induced expressions of IL-1α and MMP-9, which were found to be significantly downregulated (1.8 and 11.5 fold respectively) by the combinatorial treatment of SurR9-C84A and TSA. Conclusion: Our results confirmed that combination of SurR9-C84A with TSA worked in synergy to heal ocular injury and inflammations due to alkali burn and led to the regeneration of ocular tissue by increasing clathrin, claudin, survivin, and TGF-β and reversal of alkali burn by suppressing IL-1α and MMP-9 without inducing haze. PMID:27516741

  2. Late Cardiac Events after Childhood Cancer: Methodological Aspects of the Pan-European Study PanCareSurFup.

    PubMed

    Feijen, Elizabeth A M; Font-Gonzalez, Anna; van Dalen, Elvira C; van der Pal, Helena J H; Reulen, Raoul C; Winter, David L; Kuehni, Claudia E; Haupt, Riccardo; Alessi, Daniela; Byrne, Julianne; Bardi, Edit; Jakab, Zsuzsanna; Grabow, Desiree; Garwicz, Stanislaw; Jankovic, Momcilo; Levitt, Gill A; Skinner, Roderick; Zadravec Zaletel, Lorna; Hjorth, Lars; Tissing, Wim J E; de Vathaire, Florent; Hawkins, Mike M; Kremer, Leontien C M

    2016-01-01

    Childhood cancer survivors are at high risk of long-term adverse effects of cancer and its treatment, including cardiac events. The pan-European PanCareSurFup study determined the incidence and risk factors for cardiac events among childhood cancer survivors. The aim of this article is to describe the methodology of the cardiac cohort and nested case-control study within PanCareSurFup. Eight data providers in Europe participating in PanCareSurFup identified and validated symptomatic cardiac events in their cohorts of childhood cancer survivors. Data on symptomatic heart failure, ischemia, pericarditis, valvular disease and arrhythmia were collected and graded according to the Criteria for Adverse Events. Detailed treatment data, data on potential confounders, lifestyle related risk factors and general health problems were collected. The PanCareSurFup cardiac cohort consisted of 59,915 5-year childhood cancer survivors with malignancies diagnosed between 1940 and 2009 and classified according to the International Classification of Childhood Cancer 3. Different strategies were used to identify cardiac events such as record linkage to population/ hospital or regional based databases, and patient- and general practitioner-based questionnaires. The cardiac study of the European collaborative research project PanCareSurFup will provide the largest cohort of 5-year childhood cancer survivors with systematically ascertained and validated data on symptomatic cardiac events. The result of this study can provide information to minimize the burden of cardiac events in childhood cancer survivors by tailoring the follow-up of childhood cancer survivors at high risk of cardiac adverse events, transferring this knowledge into evidence-based clinical practice guidelines and providing a platform for future research studies in childhood cancer patients. .

  3. The Periplasmic Bacterial Molecular Chaperone SurA Adapts Its Structure to Bind Peptides in Different Conformations to Assert a Sequence Preference for Aromatic Residues

    SciTech Connect

    Xu, X.; Wang, S.; Hu, Y.-X.; McKay, D.B.

    2009-06-04

    The periplasmic molecular chaperone protein SurA facilitates correct folding and maturation of outer membrane proteins in Gram-negative bacteria. It preferentially binds peptides that have a high fraction of aromatic amino acids. Phage display selections, isothermal titration calorimetry and crystallographic structure determination have been used to elucidate the basis of the binding specificity. The peptide recognition is imparted by the first peptidyl-prolyl isomerase (PPIase) domain of SurA. Crystal structures of complexes between peptides of sequence WEYIPNV and NFTLKFWDIFRK with the first PPIase domain of the Escherichia coli SurA protein at 1.3 A resolution, and of a complex between the dodecapeptide and a SurA fragment lacking the second PPIase domain at 3.4 A resolution, have been solved. SurA binds as a monomer to the heptapeptide in an extended conformation. It binds as a dimer to the dodecapeptide in an alpha-helical conformation, predicated on a substantial structural rearrangement of the SurA protein. In both cases, side-chains of aromatic residues of the peptides contribute a large fraction of the binding interactions. SurA therefore asserts a recognition preference for aromatic amino acids in a variety of sequence configurations by adopting alternative tertiary and quaternary structures to bind peptides in different conformations.

  4. A Qualitative Case Study Illustrating the Benefits of Discussion Roles in Online Asynchronous Discussion

    ERIC Educational Resources Information Center

    Hancock, Cheryl J.

    2012-01-01

    This research describes a qualitative, naturalistic case study of a situation-specific, in-depth exploration of the use of ten student discussion roles in and adult education, online asynchronous discussions. Discussion roles were designed in order to enable students to respond better and create deeper and more meaning-filled threaded discussions,…

  5. Exploring the Use of Discussion Strategies and Labels in Asynchronous Online Discussion

    ERIC Educational Resources Information Center

    Gao, Fei

    2014-01-01

    Drawing on research in constrained online discussion environments and strategy instruction, this approach combines explicit instruction on discussion strategies with the use of post type labels. In a trial of this approach in an online course, students actively used the discussion strategies and post type labels in their discussions. Analysis of…

  6. An Elementary Discussion of Chemical Equilibrium.

    ERIC Educational Resources Information Center

    David, Carl W.

    1988-01-01

    This discussion uses a more difficult reaction as the prototype to derive the standard equation for chemical equilibrium. It can be used by students who can understand and use partial derivatives. (CW)

  7. How To Discuss Sleep With Your Doctor

    MedlinePlus

    ... from the NHLBI on Twitter. How To Discuss Sleep With Your Doctor Doctors might not detect sleep ... Rate This Content: NEXT >> Updated: June 7, 2017 Sleep Infographic Sleep Disorders & Insufficient Sleep: Improving Health through ...

  8. Building an Online Discussion Group for Teachers

    ERIC Educational Resources Information Center

    Groth, Randall E.; Bergner, Jennifer A.

    2007-01-01

    This article describes the formation of a pedagogy-focused online discussion group for middle school mathematics teachers. Advice is offered for those seeking to establish similar conversations among their colleagues.

  9. Discussion and Other Types of Talk

    ERIC Educational Resources Information Center

    Furner, Mary O.

    1971-01-01

    The author considers the various types of talk--recitation, inductive questioning, and discussion--a teacher can employ in the classroom to achieve various objectives. She urges a judicious mixture of these types. (Author/JB)

  10. Student Inquiry in a Physics Class Discussion.

    ERIC Educational Resources Information Center

    Hammer, David

    1995-01-01

    Analyzes a short excerpt from a high school physics class discussion to consider the value of the students' work as inquiry and to illustrate a teacher's negotiation of the tension between inquiry and traditional content-oriented concerns. (MDM)

  11. Dr. Irvin Yalom Discusses Group Psychotherapy.

    ERIC Educational Resources Information Center

    Forester-Miller, Holly

    1989-01-01

    In this interview, Dr. Irvin Yalom, director of the Adult Psychiatry Clinic at Stanford University School of Medicine, discusses his beginnings as a group psychotherapist, current issues in group work, and the future of group work. (Author/TE)

  12. Press Association Directors Discuss Responsibilities, Concerns.

    ERIC Educational Resources Information Center

    Dodd, Julie E.

    1989-01-01

    Discusses scholastic press association directors and high school journalism workshop directors' assessments of their duties. Offers the directors' suggestions for publication advisers--what they can do to make the life of the director less stressful. (MS)

  13. Refiners discuss HF alkylation process and issues

    SciTech Connect

    Not Available

    1992-04-06

    Safety and oxygenate operations made HF alkylation a hot topic of discussion at the most recent National Petroleum Refiners Association annual question and answer session on refining and petrochemical technology. This paper provides answers to a variety of questions regarding the mechanical, process, and safety aspects of the HF alkylation process. Among the issues discussed were mitigation techniques, removal of oxygenates from alkylation unit feed, and amylene alkylation.

  14. Divisions Panel Discussion: Astronomy for Development

    NASA Astrophysics Data System (ADS)

    Govender, Kevin; Hemenway, Mary Kay; Wolter, Anna; Haghighipour, Nader; Yan, Yihua; van Dishoeck, E. F.; Silva, David; Guinan, Edward

    2016-10-01

    The main purpose of this panel discussion was to encourage conversation around potential collaborations between the IAU Office of Astronomy for Development (OAD) and IAU Divisions. The discussion was facilitated by the OAD and the conversation revolved mainly around two questions: (i) What should the OAD be doing to enhance the work of the Divisions? (ii) What could the Divisions (both members and respective scientific discipline in general) contribute towards the implementation of the IAU strategic plan?

  15. Seasonal variability shapes resilience of small-scale fisheries in Baja California Sur, Mexico

    PubMed Central

    Leslie, Heather M.

    2017-01-01

    Small-scale fisheries are an important source of food and livelihoods to coastal communities around the world. Understanding the seasonality of fisheries catch and composition is crucial to fisheries management, particularly in the context of changing environmental and socioeconomic conditions. While seasonal variability directly impacts the lives of fishers, most fisheries studies focus on longer-term change. Here we examine seasonal variability in the small-scale fisheries of Baja California Sur, Mexico based on 13 years of government fisheries data. We investigate how four fisheries indicators with direct relevance to ecological resilience–magnitude and variance of landed fish biomass, taxon richness and the proportion of top-trophic-level taxa in total catch–vary within and among years and at multiple spatial scales. We find that these resilience indicators vary both seasonally and spatially. These results highlight the value of finer-scale monitoring and management, particularly for data-poor fisheries. PMID:28783740

  16. Metal concentrations in demersal fish species from Santa Maria Bay, Baja California Sur, Mexico (Pacific coast).

    PubMed

    Jonathan, M P; Aurioles-Gamboa, David; Villegas, Lorena Elizabeth Campos; Bohórquez-Herrera, Jimena; Hernández-Camacho, Claudia J; Sujitha, S B

    2015-10-15

    Concentrations of 11 trace metals (Fe, Mn, Cr, Cu, Ni, Co, Pb, Zn, Cd, As, Hg) in 40 fish species from Santa Maria Bay, Baja California Sur, Mexico, the strategically important area for marine mammals and organisms were analyzed. Based on their concentrations the ranking of metals Fe>Zn>Ni>Cr>Mn>Pb>Cu>Co>As>Cd>Hg suggests that organism size, metabolism and feeding habits are correlated with metal concentrations. Local geological formations affect the concentrations of different metals in the aquatic environment and are subsequently transferred to fishes. The correlation analysis suggests that metabolism and nurturing habits impact the concentration of metals. Concentrations of Fe and Mn appear to be influenced by scavenging and absorption processes, which vary by species. The considerable variability in the metal concentrations obtained in different species underscores the importance of regular monitoring.

  17. Contributions from Particles in Europe (PiE) 2010, Villefranche-sur-Mer, France: an introduction

    NASA Astrophysics Data System (ADS)

    Mikkelsen, Ole A.; Chami, Malik; Doxaran, David

    2012-04-01

    This special issue of Geo-Marine Letters presents selected contributions from the international conference Particles in Europe (PiE) 2010 organized by Sequoia Scientific, Inc., and the Laboratoire d'Océanographie de Villefranche (LOV) on 15-17 November 2010 in Villefranche-sur-Mer, France, and guest-edited by Ole Mikkelsen, Malik Chami and David Doxaran. PiE was initiated in 2008, in order to promote and further our understanding of the importance of suspended particulate matter (SPM) for a very wide range of processes in the aquatic environment—from optics and acoustics, over sediment transport, to the global carbon balance. The papers in this special issue are in particular concerned with the interaction between SPM and water optical properties, as well as how to use optical proxy measurements to understand SPM processes. The next PiE conference is scheduled for 17-19 October 2012 in Barcelona, Spain.

  18. Growing Wildfire Near Big Sur, California Imaged by NASA Terra Spacecraft

    NASA Image and Video Library

    2016-08-09

    The Soberanes fire, in Central California near Big Sur, had grown to more than 67,000 acres when the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra spacecraft captured this image on Aug. 6, 2016. More than 4,800 personnel are battling the blaze, which is now 50 percent contained. The fire has destroyed 57 homes and 11 outbuildings and caused one fatality. Evacuation orders are still in effect for a number of nearby communities. The fire was caused by an illegal unattended campfire. Vegetation is depicted in red colors; burned areas are dark grey; clouds are white; smoke and ash are light grey. Yellow indicates active fires, detected on ASTER's thermal infrared channels. The image covers an area of 19 by 26 miles (30 by 42 kilometers), and is located at 36.4 degrees north, 121.8 degrees west. http://photojournal.jpl.nasa.gov/catalog/PIA20725

  19. Amplification Raman stimulée de signaux hyperfréquences sur porteuse optique

    NASA Astrophysics Data System (ADS)

    Keïta, K.; Delaye, P.; Frey, R.; Roosen, G.; Dolfi, D.; Huignard, J.-P.

    2006-10-01

    À l'heure actuelle, lorsque l'on souhaite amplifier une porteuse optique, la solution consiste à utiliser un amplificateur à fibre dopée Erbium (EDFA). Toutefois, un problème se pose lorsque le signal modulant se trouve dans le domaine hyperfréquence car ces applications (principalement radars) demandent d'obéir à des critères de qualité très sévères. Nous démontrons ici la supériorité en termes de bruit de l'amplificateur Raman à fibre sur l'EDFA lorsqu'il s'agit d'amplifier de faibles signaux.

  20. Modern carbonate sediments and environments of the LaPaz region, Baja California Sur, Mexico

    SciTech Connect

    Halfar, J.; Ingle, J.C. Jr.; Cruz-Orozco, R.; Godinez-Orta, L.

    1996-12-31

    The Gulf of California represents one of the most productive and unique marginal seas in the world. The mouth of the Gulf captures warm equatorial water while annual wind patterns assure major upwelling of nutrient-rich water leading to a rich marine biota. These conditions have created a wide array of tropical through warm temperate carbonate environments. The most unusual of these environments is located in the La Paz region of Baja California Sur where tropical-subtropical water temperatures and low rainfall have allowed growth of corals, calcareous red algae, and other shelled invertebrates to form a carbonate bank environment. Sampling and mapping transacts in shallow bays north of La Paz and on the adjacent Espiritu Santo island have revealed a full spectrum of subenvironments including mangrove bordered, terrigenous mud dominated coastal zones, which grade into carbonate tidal flats. In addition, single coral heads as well as incipient reef structures constructed by Porites and Pocillopora coral are present in deeper water areas. Coralline red algae, which are increasingly utilized for paleoenvironmental reconstructions, grow in high abundance on coral debris and in soft sediments and turn out to be main contributors to the La Paz carbonates. Analysis of siliciclastic admixtures, grain size and organic carbon content allow a classification of distinct environments. These data are supplemented by an evaluation of benthic foraminiferal zonations and the varying abundance of biogenic constituents. This Baja California Sur carbonate environment holds special relevance for the interpretation of analogous Neogene and Paleogene paleoenvironments marking major paleoclimatic and paleoceanographic events along the Pacific Coast of North America.

  1. Modern carbonate sediments and environments of the LaPaz region, Baja California Sur, Mexico

    SciTech Connect

    Halfar, J.; Ingle, J.C. Jr. ); Cruz-Orozco, R. ); Godinez-Orta, L. )

    1996-01-01

    The Gulf of California represents one of the most productive and unique marginal seas in the world. The mouth of the Gulf captures warm equatorial water while annual wind patterns assure major upwelling of nutrient-rich water leading to a rich marine biota. These conditions have created a wide array of tropical through warm temperate carbonate environments. The most unusual of these environments is located in the La Paz region of Baja California Sur where tropical-subtropical water temperatures and low rainfall have allowed growth of corals, calcareous red algae, and other shelled invertebrates to form a carbonate bank environment. Sampling and mapping transacts in shallow bays north of La Paz and on the adjacent Espiritu Santo island have revealed a full spectrum of subenvironments including mangrove bordered, terrigenous mud dominated coastal zones, which grade into carbonate tidal flats. In addition, single coral heads as well as incipient reef structures constructed by Porites and Pocillopora coral are present in deeper water areas. Coralline red algae, which are increasingly utilized for paleoenvironmental reconstructions, grow in high abundance on coral debris and in soft sediments and turn out to be main contributors to the La Paz carbonates. Analysis of siliciclastic admixtures, grain size and organic carbon content allow a classification of distinct environments. These data are supplemented by an evaluation of benthic foraminiferal zonations and the varying abundance of biogenic constituents. This Baja California Sur carbonate environment holds special relevance for the interpretation of analogous Neogene and Paleogene paleoenvironments marking major paleoclimatic and paleoceanographic events along the Pacific Coast of North America.

  2. Etude Bacteriologique sur 30 Mois dans un Service de Brulés

    PubMed Central

    Chaibdraa, A.; Bentakouk, M.C.

    2008-01-01

    Summary Le pronostic des brûlures est souvent tributaire de complications infectieuses. Les objectifs de cette étude préliminaire rétrospective sont une évaluation de la flore microbienne et ses fluctuations selon la durée d'hospitalisation chez les patients du Centre des brûlés adultes de Annaba (Algérie). Ce travail porte sur 633 prélèvements microbiologiques positifs obtenus entre juin 2003 (inauguration du service) et décembre 2005. Selon le site de prélèvement la répartition est: cutané (78%), hémoculture (9%), prélèvement trachéo-bronchique (4%), uroculture (3%), sonde urinaire (3%), cathéter(3%). Les germes isolés sont: les staphylocoques (58%), les Pseudomonas (20%), le Candida albicans (5%), l'Acinetobacter (3%) et les autres germes (14%). Parmi les staphylocoques et les Pseudomonas recensés, respectivement 19% et 11% sont isolés la première semaine, contre 43% et 52% au-delà de 21 jours. Ces résultats confrontés aux données de la littérature confirment la prédominance du staphylocoque et du Pseudomonas. Le risque de contamination à partir des techniques invasives de réanimation est commun à toutes les équipes. La prolifération bactérienne est en relation avec la durée d'hospitalisation. Ces constatations doivent nous inciter à tirer bénéfice de l'expérience des autres services, en particulier sur les moyens, accessibles, de prévention de l'infection nosocomiale. PMID:21991102

  3. Volvulus du mesentere sur lipome mesenterique: à propos d’un cas

    PubMed Central

    Dème, Hamidou; Badji, Nfally; Akpo, Léra Géraud; Touré, Mouhamed Hamine; Draha, Ronald; Niang, Fallou Gallas; Diop, Abdoulaye Dione; Niang, El Hadj

    2016-01-01

    Nous rapportons le cas d'une patiente de 7 ans qui a consulté pour une douleur abdominale aigue paroxystique siégeant au niveau de l'épigastre associée à des vomissements sans arrêt des matières et des gaz. L'examen clinique ainsi que le bilan biologique étaient sans particularité. L'échographie abdominale demandée en première intention a montré une masse du flanc et de la fosse iliaque droite échogène, homogène à contours réguliers sans signal vasculaire au Doppler associée à un signe du tourbillon des vaisseaux mésentériques. A la tomodensitométrie cette masse correspondait à une formation lipomateuse, bien limitée, exerçant un effet de masse sur le cœcum avec volvulus du mésentère au contact. La disposition des vaisseaux mésentériques à leur origine était normale. Le diagnostic de volvulus du mésentère sur lipome a été retenu. La prise en charge chirurgicale et l'analyse anatomopathologique de la pièce opératoire a confirmé le diagnostic. Nous allons à travers ce cas clinique revoir l'apport de l'échographie et du scanner dans le diagnostic de volvulus du mésentère. PMID:28250879

  4. Recommandations sur l’examen pelvien de dépistage systématique

    PubMed Central

    Tonelli, Marcello; Gorber, Sarah Connor; Moore, Ainsley; Thombs, Brett D.

    2016-01-01

    Résumé Objectif Examiner les lignes directrices de 2014 de l’American College of Physicians (ACP) en matière d’examens pelviens de dépistage du cancer (autre que du col), des maladies inflammatoires pelviennes ou d’autres affections gynécologiques bénignes afin de déterminer si les lignes directrices de l’ACP en matière d’examens pelviens systématiques sont conformes aux normes établies par le Groupe d’étude canadien sur les soins de santé préventifs (GECSSP) et peuvent être adaptées ou adoptées. Méthodologie La méthode SNAP-IT (Smooth National Adaptation and Presentation of Guidelines to Improve Thrombosis Treatment) a servi à déterminer si les lignes directrices de l’ACP étaient conformes aux normes du GECSSP et pouvaient être adaptées ou adoptées. Recommandations Le GECSSP recommande de ne pas effectuer un examen pelvien de dépistage des cancers non cervicaux, des maladies inflammatoires pelviennes ou d’autres affections gynécologiques chez les femmes asymptomatiques. Il s’agit d’une forte recommandation reposant sur des données probantes de qualité modérée. Conclusion Le GECSSP adopte la recommandation en matière d’examen pelvien de dépistage, comme publiée par l’ACP en 2014.

  5. Segundo Catálogo Estelar del Hemisferio Sur con Astrolabio Fotoeléctrico PAII

    NASA Astrophysics Data System (ADS)

    Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.

    Recordamos que entre el Observatorio Astronómico ``Félix Aguilar'', el Observatorio Astronómico de Beijing y el Observatorio Astronómico de La Plata, se ha convenido en desarrollar un Proyecto de Investigación conjunto, para la observación sistemática de estrellas en el Hemisferio Sur, con el objeto de la elaboración de un Catálogo Estelar Global utilizando un Astrolabio Fotoeléctrico PAII del Observatorio de Beijing, que ha sido usado con éxito en la República de China. En este trabajo se presenta el Segundo Catálogo Estelar del Hemisferio Sur, derivado de las observaciones realizadas con el PAII instalado en el OAFA, durante el períiodo Febrero de 1992 a Marzo de 1997. En este lapso se han observado mas de 400000 pasajes estelares, obteniéndose las correcciones Δ α y Δ δ de 5241 estrellas del FK4, FK5, FK5 Ext., SRS, CAMC y GC. Las precisiones medias son del orden de ± 3,2 ms en ascensión recta y ±0."057 en declinación. Rango de magnitudes : 2,0 a 11,5 Rango de declinaciones : -3o a -60o Epoca Media : 1994.9 Se analizan los residuos en función de la magnitud y tipo espectral, correcciones de grupo y frecuencia de distribución Δ α y Δ δ.

  6. A Discussion of Knowledge Based Design

    NASA Technical Reports Server (NTRS)

    Wood, Richard M.; Bauer, Steven X. S.

    1999-01-01

    A discussion of knowledge and Knowledge- Based design as related to the design of aircraft is presented. The paper discusses the perceived problem with existing design studies and introduces the concepts of design and knowledge for a Knowledge- Based design system. A review of several Knowledge-Based design activities is provided. A Virtual Reality, Knowledge-Based system is proposed and reviewed. The feasibility of Virtual Reality to improve the efficiency and effectiveness of aerodynamic and multidisciplinary design, evaluation, and analysis of aircraft through the coupling of virtual reality technology and a Knowledge-Based design system is also reviewed. The final section of the paper discusses future directions for design and the role of Knowledge-Based design.

  7. Conference Discussion of the Nuclear Force

    SciTech Connect

    Franz Gross,Thomas D. Cohen,Evgeny Epelbaum,R. Machleidt

    2010-12-01

    Discussion of the nuclear force, lead by a round table consisting of T. Cohen, E. Epelbaum, R. Machleidt, and F. Gross (chair). After an invited talk by Machleidt, published elsewhere in these proceedings, brief remarks are made by Epelbaum, Cohen, and Gross, followed by discussion from the floor moderated by the chair. The chair asked the round table and the participants to focus on the following issues: (1)What does each approach (chiral effective field theory, large Nc, and relativistic phenomenology) contribute to our knowledge of the nuclear force? Do we need them all? Is any one transcendent? (2) How important for applications (few body, nuclear structure, EMC effect, for example) are precise fits to the NN data below 350 MeV? How precise do these fits have to be? (3) Can we learn anything about nonperturbative QCD from these studies of the nuclear force? The discussion presented here is based on a video recording made at the conference and transcribed afterward.

  8. [A glossary for discussion about abortion].

    PubMed

    Astete A, Carmen; Beca I, Juan Pablo; Lecaros U, Alberto

    2014-11-01

    Abortion and its diverse possible legal regulations is one of the major and toughest social controversies. This debate is even more problematic due to biases, prejudgments, different ideologies, beliefs, religious doctrines and political pressures. Chile has recently begun a new national discussion with an evident confusion, both in juridical and clinical terminology, which makes very difficult to achieve the necessary plural debate for a social and political consensus. The authors structured an academic collaborative project to create a glossary as a contribution for a discussion based on clearly defined notions about the different terms used in the abortion debate. Twenty-two concepts were selected and their definitions were reviewed and discussed by more than 50 different specialists. The final version of this glossary in Spanish language is presented.

  9. Summary of discussion of issues and needs

    SciTech Connect

    Myers, D.R.

    1995-09-01

    All participants in the Photovoltaic Radiometric Measurements Workshop were invited to critique the status reports presented by each of the speakers in turn, as well as contribute to the discussion of needs and issues at the conclusion of each day of the program. An examination of the programs shows that the workshop topics evolved from the broad perspective of radiometric standards, traceability and calibration issues to radiometric engineering (instrumentation, measurements), to resource data availability, applications, and modelling. The workshop chairman divided the discussion topics into two main areas related to the perceived radiometry related needs of the photovoltaic (PV) community: (1) Radiometry for PV Engineering Applications and (2) PV Solar Radiometric Resource Data.

  10. [Disseminated sporotrichosis - clinical case and discussion].

    PubMed

    Barroso Pereira, João Cláudio; Grijó, Amorita; Ribeiro Machado Pereira, Rosângela; Noel S Oliveira, Andreza; de Andrade, Ana Cláudia; Ferreira, Ana Cláudia M; Corrêa Brant Machado, Christiane; Veiga Coutinho, Débora; Vale Rios, Danilo; Pereira Pires, Bárbara

    2008-01-01

    The authors report a case of a patient with a prior history of alcohol abuse who developed nodules and ulcerated skin lesions on his trunk and lower extremities along the line of the lymphatic draining area. The patient's X-ray showed reticular nodular intersticial infiltrates at the lung bases. There was a positive culture of supraclavicular lymph node for Sporothrix schenckii. After specific treatment using mainly potassium iodide, there was regression of cutaneous lesions and lung infiltrates. The authors present a discussion on the deseases' forms of presentation, highlighting the lung involvement ans further discuss the diagnosis and treatment of sporotrichosis.

  11. Summary discussion: An integrated advanced tokamak reactor

    SciTech Connect

    Sauthoff, N.R.

    1994-12-31

    The tokamak concept improvement workshop addressed a wide range of issues involved in the development of a more attractive tokamak. The agenda for the workshop progressed from a general discussion of the long-range energy context (with the objective being the identification of a set of criteria and ``figures of merit`` for measuring the attractiveness of a tokamak concept) to particular opportunities for the improvement of the tokamak concept. The discussions concluded with a compilation of research program elements leading to an improved tokamak concept.

  12. Hydrogen embrittlement: future directions-discussion.

    PubMed

    Lambert, H; Chen, Y-S

    2017-07-28

    The final session of the meeting consisted of a discussion panel to propose future directions for research in the field of hydrogen embrittlement and the potential impact of this research on public policy.This article is part of the themed issue 'The challenges of hydrogen and metals'. © 2017 The Author(s).

  13. Functions of Symbolizing Activity: A Discussion

    ERIC Educational Resources Information Center

    Tillema, Erik

    2010-01-01

    I propose that attending how symbolizing activity functions for teachers and students helps to characterize student-teacher communication, and allows for an investigation of how symbolizing activity contributes to learning. I begin this discussion by articulating four ideas-schemes, symbolizing activity, communication, and learning. Then I propose…

  14. Workplace Mobbing: A Discussion for Librarians

    ERIC Educational Resources Information Center

    Hecker, Thomas E.

    2007-01-01

    Workplace mobbing occurs in libraries but is usually unrecognized and unchecked because the phenomenon has not been described and given a name. This discussion provides the library profession with an overview but also with specific background details to assist with recognizing mobbing and preventing severe harm to employees and organizations.

  15. Role Modelling in MOOC Discussion Forums

    ERIC Educational Resources Information Center

    Hecking, Tobias; Chounta, Irene-Angelica; Hoppe, H. Ulrich

    2017-01-01

    To further develop rich and expressive ways of modelling roles of contributors in discussion forums of online courses, particularly in MOOCs, networks of forum users are analyzed based on the relations of information-giving and information-seeking. Specific connection patterns that appear in the information exchange networks of forum users are…

  16. Panel discussion: The future of IR astronomy

    NASA Technical Reports Server (NTRS)

    Caroff, Lawrence J.

    1995-01-01

    A panel discussion was held on the future of IR astronomy. The chairman gave a brief introduction to current planned programs for NASA and other space agencies, followed by short contributions from the six panel members on a variety of special topics. After that, a short question and answer session was held.

  17. Discussed Issues in Preventive Intervention Programs

    ERIC Educational Resources Information Center

    Ocak, Sakire

    2011-01-01

    The growing number of studies in the field of prevention science and related advancements in evidence based programs leads to some discussions about the fundamental issues such as efficacy, effectiveness, dissemination, adaptation, fidelity and continuity in recent years. In this article it is intended to report the common views of early childhood…

  18. How to Facilitate Discussions in History

    ERIC Educational Resources Information Center

    Reisman, Abby

    2017-01-01

    In this article, Abby Reisman offers four instructional practices that educators can use to help students grapple with history's contradictions and engage in meaningful text-based discussions. Reisman details two suggestions that can be used in history classrooms and across the disciplines: orient students to one another and orient students to the…

  19. Alice, Greenfoot, and Scratch--A Discussion

    ERIC Educational Resources Information Center

    Utting, Ian; Cooper, Stephen; Kolling, Michael; Maloney, John; Resnick, Mitchel

    2010-01-01

    This article distills a discussion about the goals, mechanisms, and effects of three environments which aim to support the acquisition and development of computing concepts (problem solving and programming) in pre-University and non-technical students: Alice, Greenfoot, and Scratch. The conversation started in a special session on the topic at the…

  20. 5 Practices for Orchestrating Productive Mathematics Discussions

    ERIC Educational Resources Information Center

    Stein, Mary Kay; Smith, Margaret

    2011-01-01

    Learn the 5 practices for facilitating effective inquiry-oriented classrooms: (1) Anticipating what students will do--what strategies they will use--in solving a problem; (2) Monitoring their work as they approach the problem in class; (3) Selecting students whose strategies are worth discussing in class; (4) Sequencing those students'…

  1. Timed Partner Reading and Text Discussion

    ERIC Educational Resources Information Center

    Giovacchini, Michael

    2017-01-01

    This engaging partner-reading activity provides students with an opportunity to improve their reading comprehension and text-based discussion skills. The activity, which can be used with intermediate and advanced learners, is ideal for English language learners in content classes and is particularly useful for building foundational knowledge of a…

  2. Explorations in Mathematics, Student Discussion Guide.

    ERIC Educational Resources Information Center

    Davis, Robert B.

    This student discussion guide is intended to accompany "Explorations in Mathematics," a text for teachers. The materials in this booklet relate mainly to variables, graphs, signed numbers, logic, identities, functions and matrices. The materials were designed to be used as supplementary materials with students in grades 5 through 9. (RP)

  3. Multiphase Method for Analysing Online Discussions

    ERIC Educational Resources Information Center

    Häkkinen, P.

    2013-01-01

    Several studies have analysed and assessed online performance and discourse using quantitative and qualitative methods. Quantitative measures have typically included the analysis of participation rates and learning outcomes in terms of grades. Qualitative measures of postings, discussions and context features aim to give insights into the nature…

  4. Using Online Discussion Boards for Senior Internships

    ERIC Educational Resources Information Center

    Hurd, Amy R.; Beggs, Brent A.; Elkins, Daniel J.

    2012-01-01

    Senior internships in parks and recreation are an opportunity to put classroom knowledge to practice. However, this is likely the first time students are in a learning environment without the immediate support of faculty and peers. To alleviate this issue, online discussion boards were used to connect interns who were located across the country.…

  5. Questioning as Facilitating Strategies in Online Discussion

    ERIC Educational Resources Information Center

    Wang, Yu-Mei

    2014-01-01

    Facilitation of online discussions presents a challenge to online learning instructors. Unlike in face-to-face courses, students in online learning do not have physical contacts with instructors. They might view instructors as authoritarian figures and perceive instructor's comments as impersonal. This article details the author's personal…

  6. Group Discussion and Cooperation in Social Dilemmas.

    ERIC Educational Resources Information Center

    Bouas, Kelly S.; Komorita, S. S.

    1996-01-01

    Face-to-face discussion has been shown to increase cooperation behavior in social dilemmas. Two general explanations of this effect were tested: group identity and perception of consensus. Female undergraduate students (N=160) participated in four-person groups in one of four experimental conditions. Findings indicate the most plausible…

  7. Discussion Paper on Digital Copyright Issues.

    ERIC Educational Resources Information Center

    2001

    The Copyright Forum serves as a venue for the discussion of digital copyright issues of interest to Canadian educational institutions, libraries, archives, and museums. The Forum currently comprises 13 national associations. The members of the participating associations are both creators and users of digital intellectual content, and a number of…

  8. Future networking and cooperation summary of discussion

    Treesearch

    Roger R. Bay

    1993-01-01

    At the end of the workshop, I led a lightly structured and informal discussion concerning methods of continuing and improving communications and cooperation among workshop participants. The group specifically ad-dressed three areas: maintaining informal one-on-one direct contacts, improving the use of the ADAP computer system for mail, and the desirability of starting...

  9. Language and Music as Communication: A Discussion.

    ERIC Educational Resources Information Center

    Brown, Roger; And Others

    1979-01-01

    Roger Brown, Diana Deutsch, Warren Benson, and Ruth Day comment on the similarities and differences between verbal language and music as forms of communication. This discussion occurred at the first session of the National Symposium on the Applications of Psychology to the Teaching and Learning of Music, Ann Arbor. (SJL)

  10. School PE through Internet Discussion Forums

    ERIC Educational Resources Information Center

    Lauritsalo, Kirsti; Sääkslahti, Arja; Rasku-Puttonen, Helena

    2015-01-01

    Background: Physical education is a subject that generates strong feelings and emotions, as can be seen in written accounts of PE experiences. It is also important to listen to students' voices in the research context. Nowadays, students can be listened to in a new way--through the Internet. Various discussion forums on the Internet make it…

  11. Quality Standards for Adult Literacy. Discussion Guide.

    ERIC Educational Resources Information Center

    Ontario Ministry of Education and Training, Toronto.

    This guide was developed as a tool for group leaders to help people in their organizations participate in local discussions about literacy quality and evaluation in Ontario, Canada, as part of the Literacy Quality Standards and Evaluation Project. The guide is organized in seven sections that cover the following topics: definition of literacy;…

  12. Hydrogen embrittlement: future directions—discussion

    NASA Astrophysics Data System (ADS)

    Lambert, H.; Chen, Y.-S.

    2017-06-01

    The final session of the meeting consisted of a discussion panel to propose future directions for research in the field of hydrogen embrittlement and the potential impact of this research on public policy. This article is part of the themed issue 'The challenges of hydrogen and metals'.

  13. 48 CFR 1.102-1 - Discussion.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... framework for the System includes the Guiding Principles for the System and the supporting policies and... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Discussion. 1.102-1 Section 1.102-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL...

  14. How to Facilitate Discussions in History

    ERIC Educational Resources Information Center

    Reisman, Abby

    2017-01-01

    In this article, Abby Reisman offers four instructional practices that educators can use to help students grapple with history's contradictions and engage in meaningful text-based discussions. Reisman details two suggestions that can be used in history classrooms and across the disciplines: orient students to one another and orient students to the…

  15. A Discussion Strategy for an Online Class

    ERIC Educational Resources Information Center

    Reese-Durham, Nancy Faith

    2014-01-01

    As a former teacher of face-to-face classes now assigned to teach only online classes, Nancy Reese Durham found herself challenged to change to accommodate online learners. She was determined to provide an environment in the online class where the high level of discussion she had provided in face-to-face classes could flourish as well. Here she…

  16. School PE through Internet Discussion Forums

    ERIC Educational Resources Information Center

    Lauritsalo, Kirsti; Sääkslahti, Arja; Rasku-Puttonen, Helena

    2015-01-01

    Background: Physical education is a subject that generates strong feelings and emotions, as can be seen in written accounts of PE experiences. It is also important to listen to students' voices in the research context. Nowadays, students can be listened to in a new way--through the Internet. Various discussion forums on the Internet make it…

  17. Theses "Discussion" Sections: A Structural Move Analysis

    ERIC Educational Resources Information Center

    Nodoushan, Mohammad Ali Salmani; Khakbaz, Nafiseh

    2011-01-01

    The current study aimed at finding the probable differences between the move structure of Iranian MA graduates' thesis discussion subgenres and those of their non-Iranian counterparts, on the one hand, and those of journal paper authors, on the other. It also aimed at identifying the moves that are considered obligatory, conventional, or optional…

  18. Janet Saltzman Chafetz Plenary: Discussant Comments

    ERIC Educational Resources Information Center

    Allen, Katherine R.

    2004-01-01

    Feminist ideas and practices permeate the consciousness, relationships, and politics of women and men across continents. Certainly, they are central to work in the scientific study of family structures and processes. It is exciting to engage in discussion and debate with other feminist scholars about the relative contributions of feminist theories…

  19. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method of furnishing those supplies is not provided for in the amendment, and... providing emergency supplies of clean drinking water. Sewage treatment and disposal, and other...

  20. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method of furnishing those supplies is not provided for in the amendment, and... providing emergency supplies of clean drinking water. Sewage treatment and disposal, and other...

  1. 33 CFR 214.6 - Discussion.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SUPPLIES OF DRINKING WATER § 214.6 Discussion. (a) The amendment provides for furnishing emergency supplies of drinking water. The method of furnishing those supplies is not provided for in the amendment, and... providing emergency supplies of clean drinking water. Sewage treatment and disposal, and other...

  2. Popular Magazines Discuss Online Information Retrieval.

    ERIC Educational Resources Information Center

    Diodato, Virgil

    1984-01-01

    Examines 55 articles from 25 popular magazines such as "Better Homes and Gardens,""Business Week,""Popular Mechanics," and "Working Woman" and discusses purpose of the articles, consumer oriented online services, libraries and information centers, databases, and publishers and intermediaries. A list of the…

  3. Talking about Music: Better Questions? Better Discussions!

    ERIC Educational Resources Information Center

    Allsup, Randall Everett; Baxter Marsha

    2004-01-01

    The music classroom is the perfect setting for investigative and imaginative inquiry--for teaching students how to talk about music. Because dialogue that is done well is too dynamic to be captured in a one-dimensional model, the ideas and frameworks in this article are merely intended to serve as springboards for eliciting richer discussions in…

  4. Affordances and Constraints of Electronic Discussions.

    ERIC Educational Resources Information Center

    Hunt, Russell A.

    The most common consequence of setting up an "electronic discussion group" for a university class or a group of faculty is a flurry of initial greetings followed by an enduring silence. Only a small proportion of computer users are active and sophisticated enough to read regularly and feel disposed to participate actively. Written…

  5. What Is Formation? A Conceptual Discussion

    ERIC Educational Resources Information Center

    Sutphen, Molly; de Lange, Thomas

    2015-01-01

    This paper addresses the principles and connotations of the term "formation." In our discussion of formation, we draw on different disciplines in order to widen and deepen our understanding of the concept of formation. We also mirror the formation concept against comparable terms and draw on studies in which it has been applied in…

  6. Early Childhood Teachers Discuss the "Standards."

    ERIC Educational Resources Information Center

    Kline, Kate

    2000-01-01

    Describes kindergarten teachers' discussions revolving around the strong statement about what children know before they enter kindergarten, the focus on the number strand, the importance of communication in mathematics and the unique communication issues pertaining to young children, and the necessity of offering appropriate support for parents of…

  7. Discover Presidential Log Cabins. Teacher's Discussion Guide.

    ERIC Educational Resources Information Center

    National Park Service (Dept. of Interior), Washington, DC.

    Discover Presidential Log Cabins is a set of materials designed to help educate 6-8 grade students about the significance of three log cabin sites occupied by George Washington, Ulysses Grant, Abraham Lincoln, and Theodore Roosevelt. This teacher's discussion guide is intended for use as part of a larger, comprehensive social studies program, and…

  8. Nonlinearity in the Cochlea—Moderated Discussions

    NASA Astrophysics Data System (ADS)

    Mountain, David C.; Guinan, John J.

    2011-11-01

    Discussions moderated by the authors on the topic "Nonlinearity in the Cochlea" were held on 18 and 21 July 2011 at the 11th International Mechanics of Hearing Workshop in Williamstown, Massachusetts. The paper provides an edited transcript of the two sessions.

  9. NEUROTOXICITY OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE): DISCUSSION PAPER

    EPA Science Inventory

    This paper is a background document for a meeting of neurotoxicity experts to discuss the central nervous system effects of exposure to perchloroethylene (perc). The document reviews the literature on neurological testing of people exposed to perc occupationally in dry cleanin...

  10. Interaction in online interprofessional education case discussions.

    PubMed

    Waterston, Rosemary

    2011-07-01

    This study investigated online interaction within a curriculum unit at the University of Toronto, Canada that included an interprofessional case study discussion in a mixed-mode (face-to-face and online) format. Nine of the 81 teams that completed the four-day curriculum were selected for detailed review based on the attitudes students expressed on a survey about the value of collaborating online for enhancing their appreciation of other health care professions. Five of the teams selected were 'positive' and four were 'negative'. The responses to other survey items by members of these teams were then compared, as well as their message posting patterns and the content of their online discussions. Differences between the two sets were situated within a theoretical framework drawn from the contact theory, social interdependence theory, and the Community of Inquiry model. Institutional support in the form of facilitator involvement, individual predispositions to online and group learning, the group composition, the learning materials, task and assignment, and technical factors all affected the levels of participation online. Discourse and organizational techniques were identified that related to interactivity within the online discussions. These findings can help curriculum planners design interprofessional case studies that encourage the interactivity required for successful online discussions.

  11. Problems of Simultaneous Interpreting of Scientific Discussion.

    ERIC Educational Resources Information Center

    Chachibaia, Nelly

    This article focuses on the problems of simultaneous translation (SI) of scientific discussion at the Conference on Training Translators and Interpreters in the New Millennium, the development of which greatly depends on extralinguistic, external conference conditions. Text linguistics considers text not only as a grammatical unit larger than a…

  12. Corruptness in Education: A Tentative Discussion

    ERIC Educational Resources Information Center

    Dongping, Yang

    2004-01-01

    With more and more instances of corruptness coming to light in the field of education, corruptness in education has become an intense "hot point" of concern in society. This article is a tentative exploration into this matter. In this article, the author discusses the categories of the corruptness in education that has found widespread…

  13. NEUROTOXICITY OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE): DISCUSSION PAPER

    EPA Science Inventory

    This paper is a background document for a meeting of neurotoxicity experts to discuss the central nervous system effects of exposure to perchloroethylene (perc). The document reviews the literature on neurological testing of people exposed to perc occupationally in dry cleanin...

  14. Unseen Discussions: Artist@Hotmail.Com.

    ERIC Educational Resources Information Center

    Huberman, Anthony

    For the recent exhibition "Greater New York: New Art in New York Now," the Education Department at P.S.1 Contemporary Art Center, a large museum located in the Long Island City section of Queens, New York, organized a unique email-based discussion. The museum set up an e-mail address for most participating artists using the free…

  15. Workplace Mobbing: A Discussion for Librarians

    ERIC Educational Resources Information Center

    Hecker, Thomas E.

    2007-01-01

    Workplace mobbing occurs in libraries but is usually unrecognized and unchecked because the phenomenon has not been described and given a name. This discussion provides the library profession with an overview but also with specific background details to assist with recognizing mobbing and preventing severe harm to employees and organizations.

  16. What Is Formation? A Conceptual Discussion

    ERIC Educational Resources Information Center

    Sutphen, Molly; de Lange, Thomas

    2015-01-01

    This paper addresses the principles and connotations of the term "formation." In our discussion of formation, we draw on different disciplines in order to widen and deepen our understanding of the concept of formation. We also mirror the formation concept against comparable terms and draw on studies in which it has been applied in…

  17. Young Scientists Discuss Recent Advances, Future Challenges.

    ERIC Educational Resources Information Center

    Baum, Rudy M.

    1989-01-01

    Discusses a National Academy of Science forum at which a group of outstanding young researchers in astronomy, molecular and developmental biology, physics, chemistry, mathematics, atmospheric science, and materials science met for three days of formal presentations and informal conversations. Provides a short synopsis of major speakers. (MVL)

  18. Alice, Greenfoot, and Scratch--A Discussion

    ERIC Educational Resources Information Center

    Utting, Ian; Cooper, Stephen; Kolling, Michael; Maloney, John; Resnick, Mitchel

    2010-01-01

    This article distills a discussion about the goals, mechanisms, and effects of three environments which aim to support the acquisition and development of computing concepts (problem solving and programming) in pre-University and non-technical students: Alice, Greenfoot, and Scratch. The conversation started in a special session on the topic at the…

  19. [Discussion on logistics management of medical consumables].

    PubMed

    Deng, Sutong; Wang, Miao; Jiang, Xiali

    2011-09-01

    Management of medical consumables is an important part of modern hospital management. In modern medical behavior, drugs and medical devices act directly on the patient, and are important factors affecting the quality of medical practice. With the increasing use of medical materials, based on practical application, this article proposes the management model of medical consumables, and discusses the essence of medical materials logistics management.

  20. Young Scientists Discuss Recent Advances, Future Challenges.

    ERIC Educational Resources Information Center

    Baum, Rudy M.

    1989-01-01

    Discusses a National Academy of Science forum at which a group of outstanding young researchers in astronomy, molecular and developmental biology, physics, chemistry, mathematics, atmospheric science, and materials science met for three days of formal presentations and informal conversations. Provides a short synopsis of major speakers. (MVL)

  1. A Discussion of Population Invariance of Equating

    ERIC Educational Resources Information Center

    Petersen, Nancy S.

    2008-01-01

    This article discusses the five studies included in this issue. Each article addressed the same topic, population invariance of equating. They all used data from major standardized testing programs, and they all used essentially the same statistics to evaluate their results, namely, the root mean square difference and root expected mean square…

  2. Media Education--Discussion or Analysis?

    ERIC Educational Resources Information Center

    Ferguson, Bob

    1977-01-01

    Aspects of "liberalism" incorporating notions of balance, fairness, objectivity, and common sense are discussed in relation to the teaching of media studies. The British TV series "Looking at Television" is examined to clarify the way which the liberal ethos pervades the series to its detriment. Liberalism is shown as allowing…

  3. Principles for Community College Finance: Discussion Paper.

    ERIC Educational Resources Information Center

    Keating, Joseph P.

    In preparation for the 1987 demise of the current community college funding mechanism in California, this discussion paper reviews the current fiscal situation in the state and considers the needs that should be addressed in the finance mechanism that would become effective in July 1987. Background information is presented on the history of the…

  4. From Good to Great: Discussion Starter Tool

    ERIC Educational Resources Information Center

    Center on Great Teachers and Leaders, 2014

    2014-01-01

    In the report "From Good to Great: Exemplary Teachers Share Perspectives on Increasing Teacher Effectiveness across the Career Continuum," (See full report in ERIC at ED555657) National and State Teachers of the Year shared their views on what helped them become great teachers. This accompanying "Discussion Starter Tool" builds…

  5. Questioning as Facilitating Strategies in Online Discussion

    ERIC Educational Resources Information Center

    Wang, Yu-Mei

    2014-01-01

    Facilitation of online discussions presents a challenge to online learning instructors. Unlike in face-to-face courses, students in online learning do not have physical contacts with instructors. They might view instructors as authoritarian figures and perceive instructor's comments as impersonal. This article details the author's personal…

  6. Online Discussion Assignments Improve Students' Class Preparation

    ERIC Educational Resources Information Center

    Lineweaver, Tara T.

    2010-01-01

    To increase the number of students who read the text before class and to promote student interaction centering on text material, I developed an online discussion assignment as a required component of a cognitive psychology course. Across 2 studies, this assignment had a limited effect on examination performance, but students completing online…

  7. Online Discussion about Sexuality Education in Schools

    ERIC Educational Resources Information Center

    Broadbear, James T.; Broadbear, Barbara C.

    2012-01-01

    Sexuality education in schools continues to be a controversial issue although public debate has seemingly calmed in recent years. Dialogue about the value and purpose of sexuality education for adolescents can provide health education specialists a better understanding of public opinion and online discussion may be a potentially ideal way to…

  8. Dr. von Braun Discusses 'Bottle Suit' Concept

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Dr. Wernher von Braun (center), then Chief of the Guided Missile Development Division at Redstone Arsenal, Alabama, discusses a 'bottle suit' model with Dr. Heinz Haber (left), an expert on aviation medicine, and Willey Ley, a science writer on rocketry and space exploration. The three men were at the Disney studios appearing in the motion picture, entitled 'Man in Space.'

  9. On psychotherapist-patient sex: discussion paper.

    PubMed Central

    Palermo, G B

    1990-01-01

    The transference phenomenon as central to the problem of sex between psychotherapist and patient is discussed. Socio-semantic factors related to the evolution of psychotherapy from Freud to the present are presented. Contemporary pertinent studies are reported. Societal and legal attitudes towards offending therapists are briefly touched upon. Reflections are made and suggestions are offered for dealing with this serious issue. PMID:2250271

  10. Language and Music as Communication: A Discussion.

    ERIC Educational Resources Information Center

    Brown, Roger; And Others

    1979-01-01

    Roger Brown, Diana Deutsch, Warren Benson, and Ruth Day comment on the similarities and differences between verbal language and music as forms of communication. This discussion occurred at the first session of the National Symposium on the Applications of Psychology to the Teaching and Learning of Music, Ann Arbor. (SJL)

  11. Dr. von Braun Discusses 'Bottle Suit' Concept

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Dr. Wernher von Braun (center), then Chief of the Guided Missile Development Division at Redstone Arsenal, Alabama, discusses a 'bottle suit' model with Dr. Heinz Haber (left), an expert on aviation medicine, and Willey Ley, a science writer on rocketry and space exploration. The three men were at the Disney studios appearing in the motion picture, entitled 'Man in Space.'

  12. Indians and the Media: A Panel Discussion

    ERIC Educational Resources Information Center

    Civil Rights Digest, 1973

    1973-01-01

    An exploration of communications and the approximately one million Indian people who live in the U.S., by people in film, television, radio, and print news; condensed from the transcript of a panel discussion held July 6, 1973 in conjunction with the Smithsonian Institution's Folklife Festival in Washington, D.C. (Author/JM)

  13. Promoting Discussion in Peer Instruction: Discussion Partner Assignment and Accountability Scoring Mechanisms

    ERIC Educational Resources Information Center

    Chou, Chih-Yueh; Lin, Pin-Hsun

    2015-01-01

    Peer instruction (PI) involves students answering questions and peer discussion learning activities. PI can enhance student performance and engagement in classroom instruction. However, some students do not engage in the discussions. This study proposes two mechanisms, discussion partner assignment and accountability scoring mechanisms, to form…

  14. Promoting Discussion in Peer Instruction: Discussion Partner Assignment and Accountability Scoring Mechanisms

    ERIC Educational Resources Information Center

    Chou, Chih-Yueh; Lin, Pin-Hsun

    2015-01-01

    Peer instruction (PI) involves students answering questions and peer discussion learning activities. PI can enhance student performance and engagement in classroom instruction. However, some students do not engage in the discussions. This study proposes two mechanisms, discussion partner assignment and accountability scoring mechanisms, to form…

  15. Comparing Face to Face, Tutor Led Discussion and Online Discussion in the Classroom

    ERIC Educational Resources Information Center

    Ng, Connie S. L.; Cheung, Wing Sum

    2007-01-01

    This study explores the relative effectiveness of in class online discussion and face to face, tutor led discussion in preservice teachers' recall of concepts. Two groups of preservice teachers, who engaged in different discussion modes, were tested two weeks later on how many concepts they could recall. No significant difference in the recall…

  16. Literature Discussion as Positioning: Examining Positions in Dialogic Discussions in a Third-Grade Classroom

    ERIC Educational Resources Information Center

    Wee, Jongsun

    2010-01-01

    The purpose of the study is to examine positions of students and a teacher in dialogic discussion. In this study, dialogic discussion was defined with Bakhtin's (1981) dialogism, Nystrand's (1997) explanation of dialogically organized instruction, and Mercer's (1995) explanation of Exploratory Talk. Studies about literature discussion in…

  17. Literature Discussion as Positioning: Examining Positions in Dialogic Discussions in a Third-Grade Classroom

    ERIC Educational Resources Information Center

    Wee, Jongsun

    2010-01-01

    The purpose of the study is to examine positions of students and a teacher in dialogic discussion. In this study, dialogic discussion was defined with Bakhtin's (1981) dialogism, Nystrand's (1997) explanation of dialogically organized instruction, and Mercer's (1995) explanation of Exploratory Talk. Studies about literature discussion in…

  18. CapDEM Exercise Gamma: Results and Discussion

    DTIC Science & Technology

    2011-06-01

    internal team’ using CapDEM towards the reality of external groups using the CapDEM approach to address their own problem by themselves. The results...enable and support different internal and external configurations of the classified CEE requires further study, including both technical and security...qu’épreuve et évaluation tout à fait indépendantes, l’Exercice a moins mis l’accent sur une « équipe interne » utilisant l’approche DIGCap et il a plutôt

  19. Evaluation d'impact sur la santé et évaluation d'impact sur l'équité en santé : éventail de pratiques et questions de recherche.

    PubMed

    Villeval, Mélanie; Bidault, Elsa; Lang, Thierry

    2016-09-01

    L'Evaluation d'Impact sur la Santé (EIS) se développe au niveau international et est encore au stade émergent en France. Elle vise à évaluer les effets positifs et négatifs potentiels d'un projet, d'un programme ou d'une politique sur la santé. L'objectif est de produire des recommandations en direction des décideurs, afin d'en maximiser les effets positifs et d'en diminuer les effets négatifs. L'EIS est un moyen particulièrement intéressant d'action sur les déterminants de la santé au-delà des comportements individuels et du système de santé. Les politiques de logement, de transport, de solidarité, économiques, etc. ont, en effet, des impacts souvent non prévus sur la santé. Au-delà des effets sur la santé, l'EIS doit aussi permettre d'apprécier la distribution de ces effets dans la population.Si la préoccupation pour l'équité en santé est centrale dans l'EIS, elle reste cependant difficilement traduite en pratique. Face à cette difficulté, des démarches d'évaluation d'impact ont été développées pour renforcer la prise en compte de l'équité à chaque étape de l'EIS ou « Equity Focused Health Impact Assessment », ou prendre en compte les impacts sur les inégalités de santé de façon spécifique. Ainsi, l'Evaluation de l'Impact sur l'Equité en Santé (EIES) semble, par exemple, particulièrement intéressante pour évaluer l'impact sur les inégalités de projets dans le champ sanitaire.L'EIS et l'EIES posent de nombreuses questions de recherche, notamment autour de la réunion, dans une même démarche, du politique, du citoyen et de l'expert. La participation des populations vulnérables potentiellement affectées par la politique évaluée est une valeur centrale de l'EIS, mais pose des questions d'acceptabilité sociale. La collaboration avec les décideurs politiques est également un enjeu majeur. Les difficultés méthodologiques, notamment de quantification des impacts, peuvent constituer des freins à la promotion

  20. Overview of 3D Documentation Data and Tools available for Archaeological Researches: case study of the Romanesque Church of Dugny-sur-Meuse (France)

    NASA Astrophysics Data System (ADS)

    Macher, H.; Grussenmeyer, P.; Kraemer, C.; Guillemin, S.

    2015-08-01

    In this paper, the 3D documentation of the full structure of the Romanesque church of Dugny-sur-Meuse is discussed. In 2012 and 2013, a 3D recording project was carried out under the supervision of the Photogrammetry and Geomatics Research Group from INSA Strasbourg (France) in cooperation with C. Kraemer, archaeologist from Nancy (France). The goal of the project was on one hand to propose new solutions and tools to the archaeologists in charge of the project especially for stone by stone measurements. On the other hand, a simplified 3D model was required by the local authorities for communication purposes. To achieve these goals several techniques were applied namely GNSS measurements and accurate traverse networks, photogrammetric recordings and terrestrial laser scanning acquisitions. The various acquired data are presented in this paper. Based on these data, several deliverables are also proposed. The generation of orthoimages from plane as well as cylindrical surfaces is considered. Moreover, the workflow for the creation of a 3D simplified model is also presented.

  1. 2010 Coalition Battle Management Language Workshop (Atelier 2010 sur le langage de gestion du champ de bataille pour les operations en coalition)

    DTIC Science & Technology

    2010-02-01

    Feb 2010 2010 Coalition Battle Management Language Workshop (Atelier 2010 sur le langage de gestion du champ de bataille pour les opérations en... bataille pour les opérations en coalition) Papers presented at the NATO Modeling and Simulation Group (NMSG) Workshop held in Farnborough, United Kingdom...RTO-MP-MSG-079 ES - 3 Atelier 2010 sur le langage de gestion du champ de bataille pour les opérations en coalition (RTO-MP-MSG-079

  2. Analysis of the Characteristics of Discussion Materials that Promote Group Discussion in the Medical Humanities.

    PubMed

    Ahn, Jae Hee; Jeon, Woo Taek

    2011-12-01

    This study aims to analyze the characteristics of discussion materials that promote student participation in discussions, satisfaction with student instruction, and tutor intervention in the medical humanities. We surveyed 117 premedical students and 7 tutors who attended 4-week group discussions in the medical humanities in 2010. We described the discussion materials using the following 4 characteristics as independent variables: material type, level of understanding, interest, and quantity. Dependent variables were: student participation in the discussion, student instruction satisfaction, and tutor intervention. Correlation analysis, multiple regression analysis, and crosstab were performed using SPSS 15.0. The correlation between the characteristics of the discussion materials differed by grade. When the books were chosen as the discussion material in the instruction of first-year premedical students, the correlation between level of understanding, interest, and quantity was negative. Higher levels of understanding of the material and interest in the material led to an increase in discussion participation among both first- and second-year premedical students. Higher levels of understanding and interest of the discussion material also increased student satisfaction with the instruction, regardless of grade. Finally, levels of understanding of the material affected the degree of tutor intervention. Tutors intervened more often in discussions with first-year premedical students than with second-year premedical students. Differences in grades and the understanding of the discussion material should be considered when choosing discussion materials. Further study is required to continue the development of the discussion model and improve methods of facilitate discussion among students in the medical humanities.

  3. Hermeneutics and observation--a discussion.

    PubMed

    Nåden, Dagfinn

    2010-03-01

    This study deals with hermeneutics and observation. The purpose is to discuss some central concerns of hermeneutics in relation to observation as a research method. Attention is centred on the hermeneutic process, preunderstanding, understanding, sensitivity, the fore-conception of completeness and language. Examples from an observation study are presented. The study ends with a discussion of the importance of proceeding without haste and of silence in observational hermeneutic research. The researcher must allow oneself to be influenced by these qualities if the observations are to be undertaken in a hermeneutic spirit. Physical time must be of lesser importance than inner time. The possibility then exists for the researcher to wander the hermeneutic spiral to the greatest depth possible.

  4. How to write a discussion section?

    PubMed Central

    Şanlı, Öner; Erdem, Selçuk; Tefik, Tzevat

    2013-01-01

    Writing manuscripts to describe study outcomes, although not easy, is the main task of an academician. The aim of the present review is to outline the main aspects of writing the discussion section of a manuscript. Additionally, we address various issues regarding manuscripts in general. It is advisable to work on a manuscript regularly to avoid losing familiarity with the article. On principle, simple, clear and effective language should be used throughout the text. In addition, a pre-peer review process is recommended to obtain feedback on the manuscript. The discussion section can be written in 3 parts: an introductory paragraph, intermediate paragraphs and a conclusion paragraph. For intermediate paragraphs, a “divide and conquer” approach, meaning a full paragraph describing each of the study endpoints, can be used. In conclusion, academic writing is similar to other skills, and practice makes perfect. PMID:26328131

  5. How to write a discussion section?

    PubMed

    Şanlı, Öner; Erdem, Selçuk; Tefik, Tzevat

    2013-09-01

    Writing manuscripts to describe study outcomes, although not easy, is the main task of an academician. The aim of the present review is to outline the main aspects of writing the discussion section of a manuscript. Additionally, we address various issues regarding manuscripts in general. It is advisable to work on a manuscript regularly to avoid losing familiarity with the article. On principle, simple, clear and effective language should be used throughout the text. In addition, a pre-peer review process is recommended to obtain feedback on the manuscript. The discussion section can be written in 3 parts: an introductory paragraph, intermediate paragraphs and a conclusion paragraph. For intermediate paragraphs, a "divide and conquer" approach, meaning a full paragraph describing each of the study endpoints, can be used. In conclusion, academic writing is similar to other skills, and practice makes perfect.

  6. Developpement d'un compresseur d'hydrogene base sur le cyclage thermique des hydrures metalliques

    NASA Astrophysics Data System (ADS)

    Laurencelle, Francois

    La compression de l'hydrogene est une etape incontournable de son utilisation dans l'industrie actuelle et dans les nouvelles applications energetiques de l'hydrogene (stockage stationnaire et transport). Les compresseurs mecaniques traditionnellement utilises posent plusieurs problemes d'ingenierie, de securite et de maintenance qui pourraient etre contournes en developpant de nouvelles technologies mieux adaptees a l'hydrogene. Dans cette these, notre objectif est de developper d'un compresseur d'hydrogene base sur les hydrures metalliques pouvant etre connecte a la sortie d'un electrolyseur fonctionnant a basse pression et d'ainsi repondre au besoin de productioncompression d'hydrogene decentralisee. La methodologie du projet comprend plusieurs etapes. Premierement, nous faisons la revue bibliographique des projets impliquant des compresseurs a hydrures metalliques. Deuxiemement, a travers des travaux experimentaux, nous recherchons des hydrures permettant une compression efficace entre 20 et 80°C. Les materiaux sont synthetises par fusion a arc electrique et caracterises sur bancs d'essais d'hydrogenation. La structure de certains materiaux est aussi investiguee par rayons X, methode de B.E.T. et microscopie electronique. Troisiemement, un reacteur d'hydrures est concu de maniere a promouvoir des echanges de chaleur rapides et efficaces. Quatriemement, le prototype et son interface de controle sont construits. Cinquiemement, le compresseur est caracterise pour en evaluer les performances en termes de debit et de capacite. Les resultats obtenus sont presentes dans trois articles publies et dans le chapitre 5 de cette these. Le compresseur (article I) est base sur trois hydrures (LaNi 4.8Sn0.2, LaNi5 et MMNi4.7Al0.3 ). Celui-ci permet d'atteindre un debit de compression de 10 a 20 L d'hydrogene par heure et son efficacite est, estimee a ˜5% par rapport a un compresseur adiabatique ideal. Il a ete demontre que l'efficacite pourrait etre augmentee en utilisant un

  7. Lignes directrices canadiennes sur la rhinosinusite bactérienne aiguë

    PubMed Central

    Kaplan, Alan

    2014-01-01

    Résumé Objectif Faire un résumé clinique des lignes directrices canadiennes sur la rhinosinusite bactérienne aiguë (RSBA) qui présente des éléments d’intérêt pour les médecins de famille. Source des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique et ont rédigé des recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en la matière venant de l’extérieur, ainsi que l’aval de sociétés médicales canadiennes (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Société canadienne d’otorhinolaryngologie et de chirurgie cervicofaciale, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic de la RSBA repose sur la présence de symptômes particuliers et leur durée; l’imagerie ou une culture n’est pas nécessaire dans les cas peu compliqués. Le traitement dépend de la gravité des symptômes, notamment avec des corticostéroïdes intranasaux (CSIN) recommandés comme monothérapie pour les cas de légers à modérés, quoique leurs bienfaits soient modestes. Le recours à des CSIN accompagnés d’antibiotiques est réservé aux patients qui ne répondent pas aux CSIN après 72 heures et comme traitement initial des patients dont les symptômes sont graves. Le choix de l’antibiotique doit tenir compte du pathogène soupçonné, du risque de résistance, des problèmes concomitants et des tendances locales de la résistance aux antimicrobiens. Des thérapies d’appoint comme l’irrigation nasale avec une solution saline sont recommandées. En présence de cas réfractaires au traitement, d’épisodes récurrents et de signes de complications, on devrait demander une

  8. Croissance epitaxiale de GaAs sur substrats de Ge par epitaxie par faisceaux chimiques

    NASA Astrophysics Data System (ADS)

    Belanger, Simon

    La situation energetique et les enjeux environnementaux auxquels la societe est confrontee entrainent un interet grandissant pour la production d'electricite a partir de l'energie solaire. Parmi les technologies actuellement disponibles, la filiere du photovoltaique a concentrateur solaire (CPV pour concentrator photovoltaics) possede un rendement superieur et mi potentiel interessant a condition que ses couts de production soient competitifs. La methode d'epitaxie par faisceaux chimiques (CBE pour chemical beam epitaxy) possede plusieurs caracteristiques qui la rendent interessante pour la production a grande echelle de cellules photovoltaiques a jonctions multiples a base de semi-conducteurs III-V. Ce type de cellule possede la meilleure efficacite atteinte a ce jour et est utilise sur les satellites et les systemes photovoltaiques a concentrateur solaire (CPV) les plus efficaces. Une des principales forces de la technique CBE se trouve dans son potentiel d'efficacite d'utilisation des materiaux source qui est superieur a celui de la technique d'epitaxie qui est couramment utilisee pour la production a grande echelle de ces cellules. Ce memoire de maitrise presente les travaux effectues dans le but d'evaluer le potentiel de la technique CBE pour realiser la croissance de couches de GaAs sur des substrats de Ge. Cette croissance constitue la premiere etape de fabrication de nombreux modeles de cellules solaires a haute performance decrites plus haut. La realisation de ce projet a necessite le developpement d'un procede de preparation de surface pour les substrats de germanium, la realisation de nombreuses sceances de croissance epitaxiale et la caracterisation des materiaux obtenus par microscopie optique, microscopie a force atomique (AFM), diffraction des rayons-X a haute resolution (HRXRD), microscopie electronique a transmission (TEM), photoluminescence a basse temperature (LTPL) et spectrometrie de masse des ions secondaires (SIMS). Les experiences ont permis

  9. Finding Malicious Cyber Discussions in Social Media

    DTIC Science & Technology

    2016-02-02

    explore in this paper is to supplement metadata analysis with direct mining of discussion text using machine-learning and human language technology (HLT...dramatically reduced using natural lan- guage machine learning techniques. Using a new English text corpus containing more than 250k dis- cussions...domain. In Section 3, use-cases, text corpora, features, and classifiers are described. In Section 4, experiments and performance results are presented

  10. Michael Griffin Discusses Exploration Architecture Study

    NASA Image and Video Library

    2005-09-18

    NASA Administrator Michael Griffin discusses the results of the agency's exploration architecture study on Monday, Sept. 19, 2005, at NASA Headquarters in Washington. The study made specific design recommendations for a vehicle to carry crews into space, a family of launch vehicles to take missions to the moon and beyond, and a "lunar mission architecture" for landing on the moon. Photo Credit: (NASA/Bill Ingalls)

  11. Summary of Study Group Session Discussions

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The relationship between gravitational physiology and calcium metabolism is examined. The role of gravity on the problems of bone response, low gravity environments, calcium in plants, and the potential in animal systems for alterations in nerve and muscle function as variations in extracellular calcium levels occurred are discussed. Innovative materials for experiments on interactions between calcium and gravity, experiments that could utilize ionospheres or calcium-measuring dyes, and specific gravity calcium experiments are also addressed.

  12. Effets du titane et du niobium sur l'oxydation à 950circC d'aciers ferritiques

    NASA Astrophysics Data System (ADS)

    Issartel, C.; Buscail, H.; Caudron, E.; Cueff, R.; Riffard, F.; El Messki, S.; Karimi, N.; Antoni, L.

    2004-11-01

    Nous avons étudié l'effet du titane et du niobium sur l'oxydation à 950circC d'un acier Fe-Cr chrominoformeur. La DRX in situ montre que le titane semble s'oxyder en formant Cr{2}TiO{5} et TiO{2} qui contribuent à une augmentation de la prise de masse des échantillons. Une partie du titane issu de ces oxydes semble doper la couche de chromine. Sa présence augmente la concentration en lacunes cationiques dans la chromine et augmente donc la diffusion du chrome dans la couche. Nous avons aussi montré que le niobium n'a pas d'influence sur l'oxydation de ce type d'acier à 950circC.

  13. Interactive Workshop Discusses Nonlinear Waves and Chaos

    NASA Astrophysics Data System (ADS)

    Tsurutani, Bruce; Morales, George; Passot, Thierry

    2010-07-01

    Eighth International Nonlinear Wave Workshop; La Jolla, California, 1-5 March 2010; Nonlinear waves and chaos were the focus of a weeklong series of informal and interactive discussions at the Eighth International Nonlinear Wave Workshop (NWW8), held in California. The workshop gathered nonlinear plasma and water wave experts from the United States, France, Czech Republic, Germany, Greece, Holland, India, and Japan. Attendees were from the fields of space, laboratory, and fusion plasma physics, astrophysics, and applied mathematics. Special focus was placed on nonlinear waves and turbulence in the terrestrial environment as well as in the interstellar medium from observational, laboratory, and theoretical perspectives. Discussions covered temperature anisotropies and related instabilities, the properties and origin of the so-called dissipation range, and various coherent structures of electromagnetic as well as electrostatic nature. Reconnection and shocks were also topics of discussion, as were properties of magnetospheric whistler and chorus waves. Examples and analysis techniques for superdiffusion and subdiffusion were identified. On this last topic, a good exchange of ideas and results occurred between a water wave expert and a plasma expert, with the rest of the audience listening intently.

  14. Discussion of long-range weather prediction

    SciTech Connect

    Canavan, G.H.

    1998-09-10

    A group of scientists at Los Alamos have held a series of discussions of the issues in and prospects for improvements in Long-range Weather Predictions Enabled by Proving of the Atmosphere at High Space-Time Resolution. The group contained the requisite skills for a full evaluation, although this report presents only an informal discussion of the main technical issues. The group discussed all aspects of the proposal, which are grouped below into the headings: (1) predictability; (2) sensors and satellites, (3) DIAL and atmospheric sensing; (4) localized transponders; and (5) summary and integration. Briefly, the group agreed that the relative paucity of observations of the state of the atmosphere severely inhibits the accuracy of weather forecasts, and any program that leads to a more dense and uniform observational network is welcome. As shown in Long-range Weather more dense and uniform observational network is welcome. As shown in Long-range Weather Predictions, the pay-back of accurate long-range forecasts should more than justify the expenditure associated with improved observations and forecast models required. The essential step is to show that the needed technologies are available for field test and space qualification.

  15. Mise à jour technique sur la physiologie et l'évaluation du liquide amniotique.

    PubMed

    Lim, Kenneth I; Butt, Kimberly; Naud, Kentia; Smithies, Mila

    2017-01-01

    RéSULTATS: SOURCES DES DONNéES PROBANTES: Nous avons effectué une recherche sur MEDLINE et Kfinder pour trouver des articles pertinents, puis avons examiné les bibliographies des articles retenus, notamment des revues Cochrane et des articles de revue récents. Les données recueillies ont été analysées par le Comité d'imagerie diagnostique de la Société des obstétriciens et gynécologues du Canada. Les recommandations ont été classées selon les critères établis par le Groupe d'étude canadien sur les soins de santé préventifs (Tableau 1). AVANTAGES, DéSAVANTAGES ET COûTS: En obstétrique moderne, l'évaluation du volume de liquide amniotique par échographie fait partie intégrante de l'évaluation fœtale. Toute anomalie donne lieu à une intervention obstétricale et à des examens approfondis. Au Canada, il n'existe aucune définition normalisée associée à l'estimation du volume de liquide amniotique ni aucune approche d'évaluation uniforme. Plusieurs essais randomisés semblent indiquer que l'évaluation de poche unique, plutôt que de plusieurs poches (indice de liquide amniotique), diminue les interventions obstétricales sans augmenter l'incidence de résultats indésirables. La littérature récente laisse croire que des changements légers, mais détectables du liquide amniotique peuvent survenir une heure ou deux suivant des manœuvres physiologiques normales, ce qui pourrait expliquer la variabilité et le manque de cohérence des résultats d'évaluations répétées en peu de temps et ainsi créer de la confusion et donner lieu à d'autres examens. Le présent article vise à décrire les limites de l'évaluation du volume de liquide amniotique, à promouvoir une méthode d'évaluation normalisée et à proposer un ensemble commun de définitions. DéCLARATIONS SOMMAIRES: RECOMMANDATION. Copyright © 2017. Published by Elsevier Inc.

  16. Mise à jour sur l’utilisation clinique de la buprénorphine

    PubMed Central

    Ducharme, Simon; Fraser, Ronald; Gill, Kathryn

    2012-01-01

    Résumé Objectif Examiner les données scientifiques actuelles sur la buprénorphine-naloxone pour le traitement des troubles liés aux opioïdes, en insistant sur le contexte des soins primaires. Qualité des données On a fait une recension dans MEDLINE et la base de données Cochrane des synthèses critiques. Les données probantes sont surtout de niveau I. Message principal La buprénorphine est un agoniste partiel des récepteurs μ des opioïdes et un antagoniste des récepteurs κ des opioïdes ayant une longue demi-vie et un potentiel moins grand que la méthadone d’entraîner un usage abusif. Pour une désintoxication, la buprénorphine est au moins équivalente à la méthadone et supérieure à la clonidine. Comme thérapie de substitution, la buprénorphine est clairement supérieure au placebo. La méthadone comporte de légers avantages en ce qui a trait à la rétention en thérapie, mais une approche par étape en utilisant initialement la buprénorphine-naloxone est aussi efficace. Il est possible, sécuritaire et efficace de recourir à la buprénorphine en milieu de soins primaires. On peut obtenir l’autorisation de prescrire de la buprénorphine après avoir suivi une formation en ligne. Conclusion La buprénorphine est un agent sécuritaire et efficace pour la désintoxication en cas de dépendance aux opioïdes. Elle peut servir d’agent de première intention dans les programmes de thérapie de substitution, en raison de son potentiel plus faible d’usage abusif en comparaison d’autres opioïdes. Son efficacité en milieux de soins primaires en fait un outil thérapeutique utile pour les médecins de famille.

  17. La violence sur les réseaux canadiens de télévision

    PubMed Central

    Paquette, Guy

    2003-01-01

    La question des effets de la violence à la télévision occupe une place très importante dans l’opinion publique depuis les vingt dernières années, et des centaines d’études y ont été consacrées. Plusieurs chercheurs concluent à une influence négative de cette violence sur le comportement. Le public, les diffuseurs et les autorités politiques ont tous endossé l’idée de réduire la quantité totale de violence présentée au petit écran – en particulier dans les émissions accessibles aux enfants. Nous avons analysé un millier d’émissions de fiction présentées entre 1993 et 2001 sur les principaux réseaux généralistes de télévision au Canada : TVA et TQS ainsi que CTV et Global pour les réseaux privés français et anglais, ainsi que Radio-Canada français et anglais pour les réseaux publics. La méthodologie utilisée est l’analyse de contenu classique, où l’acte de violence constitue l’unité d’analyse. Les données recueillies démontrent que la quantité de violence a augmenté régulièrement depuis 1993, malgré la volonté affirmée des télédiffuseurs de présenter une programmation moins violente. C’est le cas du nombre brut d’actes et du nombre d’actes à l’heure, qui est lui aussi en forte croissance. Les réseaux privés véhiculent trois fois plus de violence que les réseaux publics. On constate également qu’une très forte proportion d’actes de violence figure dans des émissions qui commencent avant 21 h, et que de nombreux enfants y sont probablement exposés. Nous signalons finalement la place de plus en plus importante occupée par la violence psychologique. PMID:20020031

  18. Bio-optical profile data report coastal transition zone program, R/V Point Sur, June 15-28, 1987

    NASA Technical Reports Server (NTRS)

    Davis, Curtiss O.; Rhea, W. Joseph

    1990-01-01

    Twenty vertical profiles of the bio-optical properties of the ocean were made during a research cruise on the R/V Point Sur, June 15 to 28, 1987, as part of the Coastal Transition Zone Program off Point Arena, California. Extracted chlorophyll values were also measured at some stations to provide calibration data for the in situ fluorometer. This summary provides investigators with an overview of the data collected. The entire data set is available in digital form.

  19. Map showing coastal cliff retreat rates along the Big Sur coast, Monterey and San Luis Obispo Counties, California

    USGS Publications Warehouse

    Hapke, Cheryl J.; Green, Krystal R.

    2004-01-01

    The average coastal cliff retreat rate along the Big Sur coast is 18 ? 6 cm/yr as measured over a 52-year time period. The erosion reference features measured as the cliff edge include the well-defined cliff edges common to marine terraces, slight breaks in the slope defining the upper edge of the active lower slope, and the road grade. Cliff erosion and retreat are focused in isolated erosion hotspots that account for most of the calculated average retreat.

  20. Interacting disturbances: did sudden oak death mortality in Big Sur worsen the impacts of the 2008 basin complex wildfire?

    Treesearch

    Margaret Metz; Kerri Frangioso; Ross Meentemeyer; David. Rizzo

    2010-01-01

    In late June 2008, a large, dry lightning storm ignited thousands of fires across California. The largest of these fires became the Basin-Indians Complex Fire in Big Sur, along the State’s central coast. The fire burned over 240,000 acres (USDA Forest Service 2008) and required over a month of intense firefighting operations to contain the perimeter. Media reports and...

  1. The crystal structure of the leptospiral hypothetical protein LIC12922 reveals homology with the periplasmic chaperone SurA.

    PubMed

    Giuseppe, Priscila O; Von Atzingen, Marina; Nascimento, Ana Lúcia T O; Zanchin, Nilson I T; Guimarães, Beatriz G

    2011-02-01

    Leptospirosis is a world spread zoonosis caused by members of the genus Leptospira. Although leptospires were identified as the causal agent of leptospirosis almost 100 years ago, little is known about their biology, which hinders the development of new treatment and prevention strategies. One of the several aspects of the leptospiral biology not yet elucidated is the process by which outer membrane proteins (OMPs) traverse the periplasm and are inserted into the outer membrane. The crystal structure determination of the conserved hypothetical protein LIC12922 from Leptospira interrogans revealed a two domain protein homologous to the Escherichia coli periplasmic chaperone SurA. The LIC12922 NC-domain is structurally related to the chaperone modules of E. coli SurA and trigger factor, whereas the parvulin domain is devoid of peptidyl prolyl cis-trans isomerase activity. Phylogenetic analyses suggest a relationship between LIC12922 and the chaperones PrsA, PpiD and SurA. Based on our structural and evolutionary analyses, we postulate that LIC12922 is a periplasmic chaperone involved in OMPs biogenesis in Leptospira spp. Since LIC12922 homologs were identified in all spirochetal genomes sequenced to date, this assumption may have implications for the OMPs biogenesis studies not only in leptospires but in the entire Phylum Spirochaetes. Copyright © 2010 Elsevier Inc. All rights reserved.

  2. PDII- Additional discussion of the dynamic aperture

    SciTech Connect

    Norman M. Gelfand

    2002-07-23

    This note is in the nature of an addition to the dynamic aperture calculations found in the report on the Proton Driver, FERMILAB-TM-2169. A extensive discussion of the Proton Driver lattice, as well as the nomenclature used to describe it can be found in TM-2169. Basically the proposed lattice is a racetrack design with the two arcs joined by two long straight sections. The straight sections are dispersion free. Tracking studies were undertaken with the objective of computing the dynamic aperture for the lattice and some of the results have been incorporated into TM-2169. This note is a more extensive report of those calculations.

  3. A discussion of the concept of spirituality.

    PubMed

    Delgado, Cheryl

    2005-04-01

    The purpose of this article is to discuss the concept of spirituality. There is a recognized connection between spirituality and health, and nurse leaders have acknowledged the importance of the spiritual as well as the physical in providing optimal nursing care. Spirituality goes beyond religious or cultural boundaries. Spirituality is characterized by faith, a search for meaning and purpose in life, a sense of connection with others, and a transcendence of self, resulting in a sense of inner peace and well-being. A strong spiritual connection may improve one's sense of satisfaction with life or enable accommodation to disability.

  4. [Discussion of leakage current measurement earthing].

    PubMed

    Li, Yuming; Zhou, Jian

    2011-11-01

    According to the measurement requirements of leakage current from the national standards such as Standard GB9706.1-2007, this article describes the existing problems of isolated power earthing during leakage current measurement. Aiming at improving the measurement accuracy and protecting the security of testing engineers, we analyses several methods for isolated power earthing during the leakage current measurement, and various reasons of possible differences among test values of leakage current. Based on the existing national standards, this article proposes alternative testing methods for discussion.

  5. The Reality of Neandertal Symbolic Behavior at the Grotte du Renne, Arcy-sur-Cure, France

    PubMed Central

    Caron, François; d'Errico, Francesco; Del Moral, Pierre; Santos, Frédéric; Zilhão, João

    2011-01-01

    Background The question of whether symbolically mediated behavior is exclusive to modern humans or shared with anatomically archaic populations such as the Neandertals is hotly debated. At the Grotte du Renne, Arcy-sur-Cure, France, the Châtelperronian levels contain Neandertal remains and large numbers of personal ornaments, decorated bone tools and colorants, but it has been suggested that this association reflects intrusion of the symbolic artifacts from the overlying Protoaurignacian and/or of the Neandertal remains from the underlying Mousterian. Methodology/Principal Findings We tested these hypotheses against the horizontal and vertical distributions of the various categories of diagnostic finds and statistically assessed the probability that the Châtelperronian levels are of mixed composition. Our results reject that the associations result from large or small scale, localized or generalized post-depositional displacement, and they imply that incomplete sample decontamination is the parsimonious explanation for the stratigraphic anomalies seen in the radiocarbon dating of the sequence. Conclusions/Significance The symbolic artifacts in the Châtelperronian of the Grotte du Renne are indeed Neandertal material culture. PMID:21738702

  6. Uranium-series ages of marine terraces, La Paz Peninsula, Baja California Sur, Mexico

    USGS Publications Warehouse

    Sirkin, L.; Szabo, B. J.; Padilla, G.A.; Pedrin, S.A.; Diaz, E.R.

    1990-01-01

    Uranium-series dating of coral samples from raised marine terrace deposits between 1.5 and 10 m above sea level in the La Paz Peninsula area, Baja California Sur, yielded ages between 123 ka and 138 ka that are in agreement with previously reported results. The stratigraphy and ages of marine units near the El Coyote Arroyo indicate the presence of two high stands of the sea during the last interglacial or oxygen isotope substage 5e at about 140 ka and 123 ka. Accepting 5 m for the sea level during the last interglacial transgression, we calculate average uplift rates for the marine terraces of about ???70 mm/ka and 40 mm/ka. These slow rates of uplift indicate a relative stability of the La Paz peninsula area for the past 140 000 years. In contrast, areas of Baja California affected by major faultf experienced higher rates of uplift. Rockwell et al. (1987) reported vertical uplift rates of 180 to 300 mm/ka at Punta Banda within the Aqua Blanea fault zone in northern Baja California. ?? 1990 Springer-Verlag.

  7. Relevamiento total del hemisferio sur celeste en la frecuencia de 1420 MHz

    NASA Astrophysics Data System (ADS)

    Bava, J. A.; Colomb, F. R.; Hurrel, E.; Larrarte, J. J.; Sanz, A. J.; Testori, J. C.; Reich, P.; Reich, W.; Wielebinski, R.

    En el presente artículo se describe el relevamiento del cielo en el Hemisferio Sur Celeste en la frecuencia de 1420 MHz para declinaciones δ<= -19o realizado con la Antena II de 30 metros de diámetro del IAR. Este relevamiento posee igual sensibilidad (3xr.m.s=50 mK) que el realizado en el Hemisferio Norte con el radiotelescopio de 25 metros de Stockert de la Universidad de Bonn, operado por el Max-Planck Institute für Radioastronomie ( Reich W., 1982, A&ASS 48, 219; Reich P. and Reich W., 1986, A&ASS 63, 205). Con los datos obtenidos por ambos radiotelescopios se posee una base de datos de todo el cielo en esta frecuencia. En esta publicación presentamos los detalles del sistema receptor, técnicas de observación y reducción de datos, calibración y discusión de los errores en los resultados.

  8. The two Coissac's novels : l'Envol and Sur la Lune

    NASA Astrophysics Data System (ADS)

    Villain, Jacques

    2002-01-01

    Coissac wrote two novels with his friend Charles Rouch.: "L'Envol" in 1934 and "Sur la Lune" in 1935. In these books he describes the preparation of the lunar rocket weigthing 3000 tons and powered by solid propellants. This rocket is launched from a base built at the top of a peruvian volcano. The seven men crew (5 french and one american) is sent to the Moon in a 45 tons command module from which two lunar modules can be separated and can descent to the lunar surface. Coissac describes along the trajectory the means to guide and control the rocket. The exploration of the Moon is done with bicycles ans suits. The explorers meet strange animals and strange people living under ground like termites in perfect love and happiness. After having explored the two faces of the Moon, the lunar modules leave the Moon for a docking with the main vehicle waiting on a lunar orbit and the crew comes back to the Earth. The spacecraft lands in the Pacific Ocean. Except the direct flight from Earth to the Moon, the travel to the Moon proposed by Coissac is very similar to that of Apollo but more than thirty years earlier.

  9. Geothermal Exploration Using Remote Sensing in the South of Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Báncora, Cristina; Prol-Ledesma, Rosa María

    2008-05-01

    The area from Ciudad Constitución to Los Cabos in Baja California Sur was studied using a mosaic of four Landsat ETM+images. The main objective was to define favorable areas for utilization and exploitation of geothermal energy. The approach was to spectrally and spatially enhance the images to define characteristics related with geothermal activity, as are the presence of altered rock and main geological structures. The products of hydrothermal alteration are minerals that belong to two main groups: oxides and hydroxyls. Therefore, image processing is necessary to enhance oxides and hydroxyls spectral features and subdue the vegetation spectral characteristics. The band subtraction (4-3, 3-1, 5-7) gave the finest results due to the fact that it is a linear equation that does not cause loss of information when it is stretched. A color composite was done with these three layers and after a detailed visual analysis three areas were point out to be prospective to contain hydrothermal activity.

  10. Isostatic gravity map of the Point Sur 30 x 60 quadrangle and adjacent areas, California

    USGS Publications Warehouse

    Watt, J.T.; Morin, R.L.; Langenheim, V.E.

    2011-01-01

    This isostatic residual gravity map is part of a regional effort to investigate the tectonics and water resources of the central Coast Range. This map serves as a basis for modeling the shape of basins and for determining the location and geometry of faults in the area. Local spatial variations in the Earth's gravity field (after removing variations caused by instrument drift, earth-tides, latitude, elevation, terrain, and deep crustal structure), as expressed by the isostatic anomaly, reflect the distribution of densities in the mid- to upper crust, which in turn can be related to rock type. Steep gradients in the isostatic gravity field often indicate lithologic or structural boundaries. Gravity highs reflect the Mesozoic granitic and Franciscan Complex basement rocks that comprise both the northwest-trending Santa Lucia and Gabilan Ranges, whereas gravity lows in Salinas Valley and the offshore basins reflect the thick accumulations of low-density alluvial and marine sediment. Gravity lows also occur where there are thick deposits of low-density Monterey Formation in the hills southeast of Arroyo Seco (>2 km, Marion, 1986). Within the map area, isostatic residual gravity values range from approximately -60 mGal offshore in the northern part of the Sur basin to approximately 22 mGal in the Santa Lucia Range.

  11. Kinetic development of biofilm on NF membranes at the Méry-sur-Oise plant, France.

    PubMed

    Houari, Ahmed; Seyer, Damien; Kecili, Karima; Heim, Véronique; Martino, Patrick Di

    2013-01-01

    The kinetic formation of biofilms developing on nanofiltration (NF) membranes was studied for 2 years in the water production unit of Méry-sur-Oise, France. New membranes were set up in a pilot train integrated to the plant and autopsied after operation for 7, 80, 475 and 717 days. The biofouling layer was studied by confocal laser scanning microscope after 4',6-diamidino-2-phenyindole dihydrochloride and lectin staining, and by attenuated total reflectance-Fourier transform infrared spectroscopy and rheology experiments. Three stages of biofilm growth were discriminated: (1) the presence of sessile microcolonies embedded in an exopolymeric matrix (after filtration for seven days); (2) membrane coverage expansion through microcolony development and biofilm growth in three dimensions (up to 80 days filtration); and (3) biofilm maturation by densification (after filtration for 80-717 days). Biofilm maturation resulted in total coverage of the membrane surface and matrix residue diversification, development of the polysaccharide network, and the strengthening of matrix cohesion through viscosity and elasticity increases. The wettability and permeability of the fouled NF membranes decreased quickly and continuously throughout the biofilm development process. The longitudinal pressure drop (LPD) increased only after the biofilm reached a quantitative threshold. The decline in membrane permeability may be the result of contributions from many fouling mechanisms but the LPD was more substantially influenced by biofilm development.

  12. When Marcel Mauss's Essai sur le Don becomes The Gift: variations on the theme of solidarity.

    PubMed

    Bateman, Simone

    2016-12-01

    Since the early 1970s, Marcel Mauss's Essai sur le Don (1923), translated into English as The Gift in 1954, has been a standard reference in the social science and bioethical literature on the use of human body parts and substances for medical and research purposes. At that time, three social scientists-political scientist Richard Titmuss in the United Kingdom and sociologist Renée C. Fox working with historian Judith Swazey in the United States-had the idea of using this concept to highlight the fundamental structure of the biomedical practices they were studying, respectively, blood donation, and hemodialysis and organ transplantation. The fact that these first applications of Mauss's essay should emerge in English- rather than in French-speaking countries raises the question of what the translation of the essay, and notably of the word don as gift, may have to do with this fact. Reading Mauss in translation undoubtedly inspired a seminal approach to interpreting medical and research practices based on bodily giving. This article posits that something may have also been lost: a much broader concept of giving with unquestionable links to the Durkheimian concept of solidarity, which Mauss conceptualizes not only as an obligation but also as a liberty to give.

  13. [Distribution of aquatic and raptor birds in a freshwater artificial pond of Baja California Sur, Mexico].

    PubMed

    Castillo-Guerrero, J A; Carmona, R

    2001-01-01

    We determined the taxonomic composition and spatial-temporal distribution of aquatic and raptor birds in a freshwater artificial pond of El Centenario, Baja California Sur, México, during 24 biweekly censuses (April, 1998 to March, 1999). The pond is particularly attractive for birds because of its variety of food items. A total 25,563 records of 69 species were done, among them the first report of Chlidonias niger and Phalaropus tricolor for the region. Species richness and abundance were determined for the migrant component, mostly Anatidae (16 species and 55.6% of the total abundance) and shorebirds (18 species and 13.3%). The greater number of species and individuals was in C the deepest and more heterogeneous section of the pond. The most important species was Oxyura jamaicensis (30% of the total observed individuals), with highest abundance in the peninsula. The artificial pond presented an atypical and distinct ornithological composition because it is located in an arid region, and acts as a resting site for migrant birds. The site included species that usually live in freshwater and coastal areas, a characteristic reflected in their high richness. It contributes noticeably to the local avian biodiversity.

  14. Abdomen aigu sur une torsion de rate ectopique: à propos d'un cas

    PubMed Central

    Khalid, Elhattabi; Fatimazahra, Bensardi; Rachid, Lefriyekh; Abdelaziz, Fadil; Mohamed, Lahkim; Nadia, Benissa; Driss, Khaiz; Saad, Berrada; Najib, Zerouali Ouariti

    2012-01-01

    La rate ectopique est une entité rare dont l'incidence est mal connue. La torsion de son pédicule est une complication grave, qui doit bénéficier d'un diagnostic précoce; évitant ainsi la splénectomie surtout chez des patients jeunes. Nous rapportons le cas d'une patiente âgée de 39 ans; admise aux urgences dans un tableau d'abdomen aigu chirurgical, l'examen clinique, l’échographie et la tomodensitométrie abdominale ont contribué au diagnostic de torsion d'une rate ectopique en position hypogastrique, la splénectomie a été réalisée devant la découverte peropératoire de taches de nécrose sur la rate tordue. Le diagnostic de torsion d'une rate ectopique doit être suspecté devant l'association d'un abdomen aigu et la palpation d'une masse abdominale. L’échographie et la tomodensitométrie abdominale confirment le diagnostic. Le traitement est chirurgical; il consiste en une splénopexie qui est plus approprié. En présence de nécrose, la splénectomie doit être réalisée aussi bien par voie laparoscopique que par laparotomie. PMID:22655096

  15. Discussing Health Care Costs with Patients

    PubMed Central

    Hardee, James T; Platt, Frederic W; Kasper, Ilene K

    2005-01-01

    Escalating health care costs are affecting patients across the country. As employers and insurance companies face higher expenses, they may move to a cost-sharing strategy, which potentially increases financial burdens on patients. In this situation, physicians may find themselves serving as both medical and financial advisors for their patients. Clinical encounters in which patients experience financial hardship can be awkward and frustrating for both parties. Physicians must learn to discuss issues of affordability in a manner that builds, rather than detracts, from a therapeutic alliance. This article describes our experiences using several communication skills that can help in the discussion of health care costs with patients. The primary skill, empathic communication, which includes “we” statements and “I wish …” statements, serves to create a platform for shared decision-making, negotiation, and a search for alternatives. In addition, it is helpful if physician offices have resource materials available and strategies identified to assist patients facing financial hardship. PMID:16050867

  16. Best friends' discussions of social dilemmas.

    PubMed

    McDonald, Kristina L; Malti, Tina; Killen, Melanie; Rubin, Kenneth H

    2014-02-01

    Peer relationships, particularly friendships, have been theorized to contribute to how children and adolescents think about social and moral issues. The current study examined how young adolescent best friends (191 dyads; 53.4% female) reason together about multifaceted social dilemmas and how their reasoning is related to friendship quality. Mutually-recognized friendship dyads were videotaped discussing dilemmas entailing moral, social-conventional and prudential/pragmatic issues. Both dyad members completed a self-report measure of friendship quality. Dyadic data analyses guided by the Actor-Partner Interdependence Model indicated that adolescent and friend reports of friendship qualities were related to the forms of reasoning used during discussion. Friends who both reported that they could resolve conflicts in a constructive way were more likely to use moral reasoning than friends who reported that their conflict resolution was poor or disagreed on the quality of their conflict resolution. The findings provide evidence for the important role that friendship interaction may play in adolescents' social and moral development.

  17. Student decision making in large group discussion

    NASA Astrophysics Data System (ADS)

    Kustusch, Mary Bridget; Ptak, Corey; Sayre, Eleanor C.; Franklin, Scott V.

    2015-04-01

    It is increasingly common in physics classes for students to work together to solve problems and perform laboratory experiments. When students work together, they need to negotiate the roles and decision making within the group. We examine how a large group of students negotiates authority as part of their two week summer College Readiness Program at Rochester Institute of Technology. The program is designed to develop metacognitive skills in first generation and Deaf and hard-of-hearing (DHH) STEM undergraduates through cooperative group work, laboratory experimentation, and explicit reflection exercises. On the first full day of the program, the students collaboratively developed a sign for the word ``metacognition'' for which there is not a sign in American Sign Language. This presentation will focus on three aspects of the ensuing discussion: (1) how the instructor communicated expectations about decision making; (2) how the instructor promoted student-driven decision making rather than instructor-driven policy; and (3) one student's shifts in decision making behavior. We conclude by discussing implications of this research for activity-based physics instruction.

  18. Accelerating Cleanup: Focus on 2006. Discussion draft

    SciTech Connect

    1997-06-01

    This executive summary addresses the activities associated with the National Transuranic (TRU) Program managed by the Carlsbad Area Office (CAO). The CAO programmatically reports to the Assistant Secretary for Environmental Management and receives administrative support through the Albuquerque Operations Office. The mission of the Carlsbad Area Office (CAO) is to protect human health and the environment by opening and operating the Waste Isolation Pilot Plant for site disposal of TRU waste and by establishing an effective system for management of TRU waste from generation to disposal. It includes personnel assigned to the CAO, the Waste Isolation Pilot Plant (WIPP) site operations, and other activities associated with the National TRU Program. The CAO develops and directs implementation of the program, while the DOE Headquarters establishes policy and guidelines. The CAO assesses compliance with the program guidance, as well as the commonality of activities and assumptions among all the sites. Since the development of the February 28, 1997, database used to develop this Discussion Draft, the opening of the WIPP facility for receipt of Contact Handled waste has been delayed from November 1997 to May 1998. This slippage is significant enough to require a change in the milestones and volumes included in the documents to be reviewed by our stakeholders. Changes have been incorporated into this Discussion Draft and its supporting Project Baseline Summaries (PBSs).

  19. Disgust discussed: introduction to the special section.

    PubMed

    Pole, Nnamdi

    2013-03-01

    The author introduces a special section of Psychological Bulletin devoted to the study of disgust. After discussing conflicts between its supposed role as a basic emotion and its more recently understood involvement in responding to moral transgressions, the author summarizes 3 articles contained in the special section. Widen and Russell (2013) present a developmental account of disgust highlighting the ages at which children experience, express, understand, verbalize, and recognize disgust. The article shows that disgust is present early but that recognition of disgust in others is considerably delayed. Chapman and Anderson (2013) review evidence pertaining to the question of whether genuine disgust is elicited by moral transgressions. Their review covers data from self-report, brain imaging, facial behavior, and implicit measures gathered from both experimental and correlational studies. They conclude that moral transgressions elicit genuine disgust. Russell and Giner-Sorolla (2013) ask what types of moral transgressions are most likely to elicit pure disgust. They find that moral transgressions involving body violations are more likely than others to elicit such disgust. Moreover, they suggest that disgust elicited by body violations is likely to be more resistant to modification by context, situation, and efforts at rationalization. Taken together, the reviews support the view that rudiments of disgust to physical objects are present early in life but later become adapted to social influence and new moral purposes. Social implications are discussed. © 2013 American Psychological Association

  20. Panel Discussion on Multi-Disciplinary Analysis

    NASA Technical Reports Server (NTRS)

    Garcia, Robert

    2002-01-01

    The Marshall Space Flight Center (MSFC) is hosting the Thermal and Fluids Analysis Workshop (TFAWS) during the week of September 10, 2001. Included in this year's TFAWS is a panel session on Multidisciplinary Analysis techniques. The intent is to provide an opportunity for the users to gain information as to what product may be best suited for their applications environment and to provide feedback to you, the developers, on future desired developments. Potential users of multidisciplinary analysis (MDA) techniques are often overwhelmed by the number of choices available to them via commercial products and by the pace of new developments in this area. The purpose of this panel session is to provide a forum wherein MDA tools available and under development can be discussed, compared, and contrasted. The intent of this panel is to provide the end-user with the information necessary to make educated decisions on how to proceed with selecting their MDA tool. It is anticipated that the discussions this year will focus on MDA techniques that couple discipline codes or algorithms (as opposed to monolithic, unified MDA approaches). The MDA developers will be asked to prepare a product overview presentation addressing specific questions provided by the panel organizers. The purpose of these questions will be to establish the method employed by the particular MDA technique for communication between the discipline codes, to establish the similarities and differences amongst the various approaches, and to establish the range of experience and applications for each particular MDA approach.

  1. Best Friends’ Discussions of Social Dilemmas

    PubMed Central

    McDonald, Kristina L.; Malti, Tina; Killen, Melanie; Rubin, Kenneth H.

    2013-01-01

    Peer relationships, particularly friendships, have been theorized to contribute to how children and adolescents think about social and moral issues. The current study examined how young adolescent best friends (191 dyads; 53.4% female) reason together about multifaceted social dilemmas and how their reasoning is related to friendship quality. Mutually-recognized friendship dyads were videotaped discussing dilemmas entailing moral, social-conventional and prudential/pragmatic issues. Both dyad members completed a self-report measure of friendship quality. Dyadic data analyses guided by the Actor-Partner Interdependence Model indicated that adolescent and friend's reports of friendship qualities were related to the forms of reasoning used during discussion. Friends who both reported that they could resolve conflicts in a constructive way were more likely to use moral reasoning than friends who reported that their conflict resolution was poor or disagreed on the quality of their conflict resolution. The findings provide evidence for the important role that friendship interaction may play in adolescents’ social and moral development. PMID:23666555

  2. Just a routine operation: a critical discussion.

    PubMed

    McClelland, G; Smith, M B

    2016-05-01

    This article has summarised a critical discussion of the human factors that contributed to the death of a patient from a failure to respond appropriately to a 'can't intubate, can't ventilate' scenario. The contributory factors included the clinical team's inability to communicate, prioritise tasks and demonstrate effective leadership and assertive followership. The film Just a routine operation has now been in circulation for several years. When a system is designed and introduced with the intention of making a change to clinical practice, it can quickly become just another component of an organisation's architecture and complacency around its use can develop. This article has been written specifically for perioperative practitioners to renew the debate around the human factors that contribute to patient harm. By critically discussing Just a routine operation and attempting to review why the incident occurred, this article has attempted to emphasise that some of the conditions and behaviours that contributed to the death of Elaine Bromiley may be latent within our organisations and teams, and may continue to contribute to failures that affect patient safety.

  3. Consensus canadien sur la nutrition féminine : adolescence, reproduction, ménopause et au-delà.

    PubMed

    O'Connor, Deborah L; Blake, Jennifer; Bell, Rhonda; Bowen, Angela; Callum, Jeannie; Fenton, Shanna; Gray-Donald, Katherine; Rossiter, Melissa; Adamo, Kristi; Brett, Kendra; Khatri, Nasreen; Robinson, Nicole; Tumback, Lindsay; Cheung, Anthony

    2016-06-01

    Doter les professionnels de la santé du Canada de connaissances et d'outils de base, afin qu'ils puissent prodiguer des conseils nutritionnels aux femmes tout au long de leur cycle de vie. RéSULTATS: L'alimentation optimale a fait l'objet d'une évaluation tout au long du cycle de vie de la femme. Elle a porté en particulier sur l'adolescence, la préconception, la grossesse, la période post-partum, la ménopause et au-delà. Le présent guide fournit d'abord des directives abrégées à l'intention de toutes les femmes. Elles sont suivies de chapitres proposant un examen des données probantes, ainsi que des recommandations sur la promotion d'une alimentation saine et d'un poids santé à chaque étape de la vie. Par ailleurs, tous les chapitres présentent une analyse de nutriments d'intérêt particulier, ainsi que d'autres aspects uniques à chaque étape de la vie. DONNéES PROBANTES: Des documents publiés, des rapports d'organismes gouvernementaux et de santé, des lignes directrices de pratique clinique, de la documentation parallèle et des extraits de manuels ont servi à étayer les recommandations formulées dans le présent document. L'évaluation de la qualité des données probantes repose sur les critères décrits dans le rapport du Groupe d'étude canadien sur les soins de santé préventifs. CHAPITRE 2 : CONSEILS GéNéRAUX SUR L'ALIMENTATION FéMININE: Déclarations Sommaires Recommandations CHAPITRE 3 : ALIMENTATION DE L'ADOLESCENTE: Déclarations Sommaires Recommandations CHAPITRE 4 : ALIMENTATION PRéCONCEPTIONNELLE: Déclarations Sommaires Recommandations CHAPITRE 5 : ALIMENTATION PENDANT LA GROSSESSE: Déclarations Sommaires Recommandations CHAPITRE 6 : ALIMENTATION ET LACTATION POST-PARTUM: Déclarations Sommaires Recommandations CHAPITRE 7 : ALIMENTATION PENDANT LA MéNOPAUSE ET AU-DELà: Déclarations Sommaires Recommandations. Copyright © 2016 The Society of Obstetricians and Gynaecologists of Canada/La Société des obst

  4. More than Words: Investigating the Format of Asynchronous Discussions as Threaded Discussions or Blogs

    ERIC Educational Resources Information Center

    Clarke, Lane W.; Kinne, Lenore

    2012-01-01

    As more courses in teacher education are offered online, it is imperative that we thoughtfully consider how we structure learning activities. This study turned a critical gaze on a common element of online courses--asynchronous discussion. The authors compared two models of discursive interaction--discussion boards versus blogs--to better…

  5. Student Participation Patterns in Online Discussion: Incorporating Constructivist Discussion into Online Courses

    ERIC Educational Resources Information Center

    Kim, Hoe Kyeung; Bateman, Betzi

    2010-01-01

    The purpose of this article was to explore student participation patterns in online discussion boards related to their characteristics and question types. The characteristics of students enrolled in an online course and the impact of types of discussion questions on student posts were examined. During the 16 weeks of a course, the participation…

  6. Literature Discussion Groups: The Role of Teacher Talk in Discussing Social Issues

    ERIC Educational Resources Information Center

    Guay, Mary

    2013-01-01

    The purpose of this study was to examine how teacher talk influenced the way issues of race, culture, and disability were addressed in literature discussion groups. Discussions of one teacher with two groups of students, of varying reading levels, were studied. The research questions were: 1) How does the teacher's perspective on the students…

  7. Science in Discussions: An Analysis of the Use of Science Content in Socioscientific Discussions

    ERIC Educational Resources Information Center

    Nielsen, Jan Alexis

    2012-01-01

    This paper presents a normative pragmatics analysis of students' use of science content in eight socioscientific group discussions about human gene therapy. The specific focus of the paper is on the argumentative role that invocations of science had in the dialectics of the discussions. The analysis suggests that science content occasionally…

  8. Does the Discussion Help? The Impact of a Formally Assessed Online Discussion on Final Student Results

    ERIC Educational Resources Information Center

    Palmer, Stuart; Holt, Dale; Bray, Sharyn

    2008-01-01

    While there is agreement that participation in online asynchronous discussions can enhance student learning, it has also been identified that there is a need to investigate the impact of participation in online discussions on student course performance. This paper presents a case study based on an undergraduate engineering management unit…

  9. Designing a Discussion Environment to Enhance Connectivity and Sustainability in Asynchronous Online Discussion

    ERIC Educational Resources Information Center

    Gao, Fei

    2011-01-01

    Lack of connectivity and sustainability are two common problems in asynchronous online discussions. In this paper, the author proposes that the two problems may have to do with the structure of threaded forums, that is, the design of threaded forums may constrain participants from having well-connected and sustained discussions. A new discussion…

  10. Science in Discussions: An Analysis of the Use of Science Content in Socioscientific Discussions

    ERIC Educational Resources Information Center

    Nielsen, Jan Alexis

    2012-01-01

    This paper presents a normative pragmatics analysis of students' use of science content in eight socioscientific group discussions about human gene therapy. The specific focus of the paper is on the argumentative role that invocations of science had in the dialectics of the discussions. The analysis suggests that science content occasionally…

  11. Student Participation Patterns in Online Discussion: Incorporating Constructivist Discussion into Online Courses

    ERIC Educational Resources Information Center

    Kim, Hoe Kyeung; Bateman, Betzi

    2010-01-01

    The purpose of this article was to explore student participation patterns in online discussion boards related to their characteristics and question types. The characteristics of students enrolled in an online course and the impact of types of discussion questions on student posts were examined. During the 16 weeks of a course, the participation…

  12. Proceedings from the DRG Seminar on Robotics in the Battlefield (31st) Held on 6-8 March 1991 in Paris, France. Volume A (Actes du 31ieme Seminaire sur la Robotique du Champ de Bataille, Groupe sur la Recherche pour la Defense).

    DTIC Science & Technology

    1992-06-01

    3 1ime Seminaire sur la robotique du champ de Bataille Groupe sur la Recherche pour la Defense S92-25111 92 9 14 00O ;-" SANS CLASSIFICATION...Avanc~es (ENSTA), du 6 au 8 Mars 1991, sur le theme de la Robotique du Champ de Bataille . En juillet 1985, s𔄀tait tenu, dans les mimes lietix, tin...s dens le domaine de la Robotique dui Champ de Bataille et de mesurer les progr~s accomplis pendant cette p~riode. Le S~minaire a regroup6 prds de 230

  13. A discussion on >Calendar Lishu Jiazi<.

    NASA Astrophysics Data System (ADS)

    Liu, Ciyuan

    1996-03-01

    Calendar Lishu Jiazi< of the first century BC is the earliest calendar work survival in Chinese history. It was composed of a list which gave sexagesimal date and its fragment of the first day, number of months (12 or 13) and the winter solstice of each year for a 76 year period. The structure and meaning of the text have not been wellknown since it was set up. In this paper, the author analyzed its basic astronomical premises and, then, introduced a mathematical method by which the list was set up. According to the same mathematical logic, the author developed regulations to make the whole calendar: new-moon days, 24 solar terms, leap years and months so that one could get a complete calendar. He discussed its practicability, error and offered a simple way to improve it. He also criticized some principles of the Chinese calendar.

  14. Transgenerational epigenetic inheritance: an open discussion.

    PubMed

    Nagy, Corina; Turecki, Gustavo

    2015-08-01

    Much controversy surrounds the idea of transgenerational epigenetics. Recent papers argue that epigenetic marks acquired through experience are passed to offspring, but as in much of the field of epigenetics, there is lack of precision in the definitions and perhaps too much eagerness to translate animal research to humans. Here, we review operational definitions of transgenerational inheritance and the processes of epigenetic programing during early development. Subsequently, based on this background, we critically examine some recent findings of studies investigating transgenerational inheritance. Finally, we discuss possible mechanisms that may explain transgenerational inheritance, including transmission of an epigenetic blueprint, which may predispose offspring to specific epigenetic patterning. Taken together, we conclude that presently, the evidence suggesting that acquired epigenetic marks are passed to the subsequent generation remains limited.

  15. Converse Discusses Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Rockford, Illinois high school student, Vincent Converse, discussed his proposed Skylab experiment with Dr. Robert Head (right) and Gene Greshman of Marshall Space Flight Center (MSFC). His experiment, 'Zero Gravity Mass Measurement' used a simple leaf spring with the mass to be weighed attached to the end. The electronic package oscillated the spring at a specific rate and the results were recorded electronically. Converse was among 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment, such as that of Converse's experiment.

  16. Todd Meister Discusses Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Todd Meister(center), high school student of the Bronx High School of Science, discusses his experiment 'An Invitro Study of Selected Isolated Immune Phenomena' with his advisor, Dr. Robert Allen (right) and Henry Floyd, both of the Marshall Space Flight Center (MSFC). His experiment was aimed at discovering whether or not the absence of gravity affects the representative life processes. Meister was one of the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  17. Kathy Jackson Discusses Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Kathy Jackson, high school student from Houston, Texas, discusses her experiment with Dr. Robert Allen (left) and her scintific advisor Arthur White, both of the Marshall Space Flight Center (MSFC). Miss Jackson's experiment tested the motor sensory performance of an astronaut at various times during the Skylab flight to detect any degredation in his eye-hand coordination. She was one of the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  18. Medical humanities: an aid to ethical discussions.

    PubMed Central

    Moore, A R

    1977-01-01

    'The ethical landscape', the title given to part of a course devised by Mr. Moore, is described in full in this paper. The whole course is a new adventure in medical education designed to help students to explore the ethical problems in the practice of medicine. The 'ethical landscape' is seen through discussion based on passages from literature depicting doctors' and patients' dilemmas. As the results summarized in the tables show, the students found the course well worth while, and thought that they had gained a new insight into the problems with which they would be confronted and also into their own personalities and those of their fellow students whom previously they had only known superficially. The Chairman of the course, Mr. Moore, was also subjected to assessment from his students, because on the skill of the Chairman such a course would fail or succeed. PMID:870691

  19. Test versus analysis: A discussion of methods

    NASA Technical Reports Server (NTRS)

    Butler, T. G.

    1986-01-01

    Some techniques for comparing structural vibration data determined from test and analysis are discussed. Orthogonality is a general category of one group, correlation is a second, synthesis is a third and matrix improvement is a fourth. Advantages and short-comings of the methods are explored with suggestions as to how they can complement one another. The purpose for comparing vibration data from test and analysis for a given structure is to find out whether each is representing the dynamic properties of the structure in the same way. Specifically, whether: mode shapes are alike; the frequencies of the modes are alike; modes appear in the same frequency sequence; and if they are not alike, how to judge which to believe.

  20. Discussing and managing hematologic germ line variants.

    PubMed

    Kohlmann, Wendy; Schiffman, Joshua D

    2016-12-02

    With the introduction of genomic technologies, more hereditary cancer syndromes with hematologic malignancies are being described. Up to 10% of hematologic malignancies in children and adults may be the result of an underlying inherited genetic risk. Managing these patients with hereditary hematologic malignancies, including familial leukemia, remains a clinical challenge because there is little information about these relatively rare disorders. This article covers some of the issues related to the diagnosis and interpretation of variants associated with hereditary hematologic malignancies, including the importance of an accurate family history in interpreting genetic variants associated with disease. The challenges of screening other family members and offering the most appropriate early malignancy detection is also discussed. We now have a good opportunity to better define hereditary cancer syndromes with associated hematologic malignancies and contribute to clinically effective guidelines.

  1. Discussing and managing hematologic germ line variants.

    PubMed

    Kohlmann, Wendy; Schiffman, Joshua D

    2016-11-24

    With the introduction of genomic technologies, more hereditary cancer syndromes with hematologic malignancies are being described. Up to 10% of hematologic malignancies in children and adults may be the result of an underlying inherited genetic risk. Managing these patients with hereditary hematologic malignancies, including familial leukemia, remains a clinical challenge because there is little information about these relatively rare disorders. This article covers some of the issues related to the diagnosis and interpretation of variants associated with hereditary hematologic malignancies, including the importance of an accurate family history in interpreting genetic variants associated with disease. The challenges of screening other family members and offering the most appropriate early malignancy detection is also discussed. We now have a good opportunity to better define hereditary cancer syndromes with associated hematologic malignancies and contribute to clinically effective guidelines.

  2. Discussion on ``Teaching the Second Law''

    NASA Astrophysics Data System (ADS)

    Silbey, Robert; Beretta, Gian Paolo; Cengel, Yunus; Foley, Andrew; Gyftopoulos, Elias P.; Hatsopoulos, George N.; Keck, James C.; Lewins, Jeffery; Lior, Noam; Nieuwenhuizen, Theodorus M.; Steinfeld, Jeffrey; von Spakovsky, Michael R.; Wang, Lin-Shu; Zanchini, Enzo

    2008-08-01

    This article reports an open discussion that took place during the Keenan Symposium "Meeting the Entropy Challenge" (held in Cambridge, Massachusetts, on October 5, 2007) following the short presentations—each reported as a separate article in the present volume—by Joseph Smith Jr., Howard Butler, Andrew Foley, Kimberly Hamad-Schifferli, Bernhardt Trout, Jeffery Lewins, Enzo Zanchini, and Michael von Spakovsky. All panelists and the audience were asked to address the following questions • Why is the second law taught in so many different ways? Why so many textbooks on thermodynamics? Why so many schools of thought? • Some say that thermodynamics is limited to equilibrium, others that it extends to nonequilibrium. How is entropy defined for nonequilibrium states?

  3. Avoiding the Theory Trap When Discussing Evolution

    NASA Astrophysics Data System (ADS)

    Morrison, David

    2006-02-01

    Public opinion polls tell us that we are losing the battle to explain the nature of evolution and its central role in science. One problem, I believe, is letting the opponents of evolution frame the discussion to our disadvantage. Framing involves the selective use of language or context to trigger responses, either support or opposition. As a prime example, we undercut our communications efforts with many nonscientists by defending the `theory of evolution.' Theory is the wrong word to use in addressing the public. In the contemporary U.S., theory means a hunch or idea that has not been established by evidence. It is thus no surprise that polls show that nearly three quarters of U.S. people think that ``evolution is commonly referred to as the theory of evolution because it has not yet been proven scientifically.'' Those who advocate adding ``only a theory'' disclaimers in textbooks know that to call evolution a theory is sufficient to undermine its acceptance.

  4. Use of hypnosis in criminology: discussion paper.

    PubMed Central

    Waxman, D

    1983-01-01

    Memories of events which are unremarkable may pass unrecorded or may fade with the passage of time. In any situation of stress, anxiety may cloud the memory of the incident and in the case of some intensely frightening or humiliating experience such material may not be subject to voluntary conscious recall and may be repressed. A technique for uncovering certain 'forgotten' or repressed memories with the use of hypnosis is described. A similar method has been used in order to retrieve such memories in the investigation of witnesses and victims of serious crime. Nevertheless, various aspects of the overall validity of such a procedure have been called into question and for this reason the results of numerous experiments and the conclusions arrived at in many papers are discussed. It is emphasized that a rigid code of conduct be followed if hypnosis is to be used as an investigatory tool. PMID:6864721

  5. Discussion of medical x ray picture normalization

    NASA Astrophysics Data System (ADS)

    Wang, Dezong; Xiong, Yingen; Cheng, Liping

    1996-01-01

    There is great significance in comparing medical x-ray pictures, which are taken in different periods. For the orthopaedics surgeon comparing the density of bone is one important way of clinical diagnosis. Some persons think that if these orthopaedics pictures are processed by histogram normalization their gray level and pseudo color can be compared directly. But for one picture we know that the gray distribution is different between the original picture and the processed picture. Comparing these pictures is not authentic. In this paper we discuss that subject and describe the basis of histogram normalization. The distribution on original x-ray pictures and processed pictures is provided. The methods to compare different pictures are mentioned.

  6. SU-A-BRA-05: Panel Discussion

    SciTech Connect

    Montemayor, V.

    2016-06-15

    Vic Montemayor - No one has been more passionate about improving the quality and effectiveness of the teaching of Medical Physics than Bill Hendee. It was in August of 2008 that the first AAPM Workshop on Becoming a Better Teacher of Medical Physics was held, organized and run by Bill Hendee. This was followed up in July of 2010 with a summer school on the same topic, again organized by Bill. There has been continued interest in alternate approaches to teaching medical physics since those initial gatherings. The momentum established by these workshops is made clear each year in the annual Innovation in Medical Physics Education session, which highlights work being done in all forms of medical physics education, from one-on-one residencies or classroom presentations to large-scale program revisions and on-line resources for international audiences. This symposium, presented on behalf of the Education Council, highlights the work of three finalists from past Innovation in Education sessions. Each will be presenting their approaches to and innovations in teaching medical physics. It is hoped that audience members interested in trying something new in their teaching of medical physics will find some of these ideas and approaches readily applicable to their own classrooms. Rebecca Howell - The presentation will discuss ways to maximize classroom learning, i.e., increasing the amount of material covered while also enhancing students’ understanding of the broader implications of the course topics. Specifically, the presentation will focus on two teaching methodologies, project based learning and flip learning. These teaching methods will be illustrated using an example of graduate medical physics course where both are used in conjunction with traditional lectures. Additionally, the presentation will focus on our experience implementing these methods including challenges that were overcome. Jay Burmeister - My presentation will discuss the incorporation of active

  7. Miles Discusses Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Lexington, Massachusetts high school student, Judith Miles, discusses her proposed Skylab experiment with Keith Demorest (right) and Henry Floyd, both of Marshall Space Flight Center (MSFC). In her experiment, called the 'Web Formation in Zero Gravity', called for spiders to be released into a box and their actions recorded to determine how well they adapt to the absence of gravity. Spiders are known to adapt quickly to other changes in the environment but nothing was known of their ability to adapt to weightlessness. At the same time spiders were weaving webs in Earth orbit, similar spiders were spinning webs in identical boxes on Earth under full gravity conditions. Miles was among the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab Mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  8. Miles Discusses Skylab Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Lexington, Massachusetts high school student, Judith Miles, discusses her proposed Skylab experiment with engineers and scientists during a design review of the experiment equipment. At left is Ron Pavlue of Kennedy Space Flight Center (KSC), holding a box is Keith Demorest of Marshall Space Flight Center (MSFC). Right of Miles is Dr. Raymond Gause, also of MSFC, who is Miles' scientific advisor. In her experiment, called the 'Web Formation in Zero Gravity', spiders were released into a box and their actions recorded to determine how well they adapt to the absence of gravity. Spiders are known to adapt quickly to other changes in the environment but nothing was known of their ability to adapt to weightlessness. At the same time spiders were weaving webs in Earth orbit, similar spiders were spinning webs in identical boxes on Earth under full gravity conditions. Miles was among the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  9. Discussion on ``Frontiers of the Second Law''

    NASA Astrophysics Data System (ADS)

    Lloyd, Seth; Bejan, Adrian; Bennett, Charles; Beretta, Gian Paolo; Butler, Howard; Gordon, Lyndsay; Grmela, Miroslav; Gyftopoulos, Elias P.; Hatsopoulos, George N.; Jou, David; Kjelstrup, Signe; Lior, Noam; Miller, Sam; Rubi, Miguel; Schneider, Eric D.; Sekulic, Dusan P.; Zhang, Zhuomin

    2008-08-01

    This article reports an open discussion that took place during the Keenan Symposium "Meeting the Entropy Challenge" (held in Cambridge, Massachusetts, on October 4, 2007) following the short presentations—each reported as a separate article in the present volume—by Adrian Bejan, Bjarne Andresen, Miguel Rubi, Signe Kjelstrup, David Jou, Miroslav Grmela, Lyndsay Gordon, and Eric Schneider. All panelists and the audience were asked to address the following questions • Is the second law relevant when we trap single ions, prepare, manipulate and measure single photons, excite single atoms, induce spin echoes, measure quantum entanglement? Is it possible or impossible to build Maxwell demons that beat the second law by exploiting fluctuations? • Is the maximum entropy generation principle capable of unifying nonequilibrium molecular dynamics, chemical kinetics, nonlocal and nonequilibrium rheology, biological systems, natural structures, and cosmological evolution? • Research in quantum computation and quantum information has raised many fundamental questions about the foundations of quantum theory. Are any of these questions related to the second law?

  10. Traditional Chinese medicine information digitalization discussion.

    PubMed

    Xie, Qi; Cui, Meng; Wu, Zhen-Dou; Zhao, Hong

    2010-11-01

    With the rapid development of information science, the ancient Traditional Chinese Medicine is combining with it rapidly, and forming a new discipline: Traditional Chinese Medicine (TCM) Informatics. TCM information digitalization is the process of digital processing, which uses modern information technology to obtain, process, store, and analyze TCM-related data, information, and knowledge. It gathers research, application development, and service in an integrated whole. This article systematically analyzes the key research issues of TCM informatics (e.g., on data resources, data standard, data system construction). Also, the methodology and technology of TCM information digitalization research are thoroughly discussed. The starting point of the research on traditional Chinese medical information digitalization was in question. The research from the current study research was drawn from collected information that was stored, transferred, and utilized. This process helped to place an emphasis on the topic, as well as extending its research areas. In addition, an innovative TCM information virtual study center was set up to support a great deal of fundamental work.

  11. Miles Discusses Skylab Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Lexington, Massachusetts high school student, Judith Miles, discusses her proposed Skylab experiment with engineers and scientists during a design review of the experiment equipment. At left is Ron Pavlue of Kennedy Space Flight Center (KSC), holding a box is Keith Demorest of Marshall Space Flight Center (MSFC). Right of Miles is Dr. Raymond Gause, also of MSFC, who is Miles' scientific advisor. In her experiment, called the 'Web Formation in Zero Gravity', spiders were released into a box and their actions recorded to determine how well they adapt to the absence of gravity. Spiders are known to adapt quickly to other changes in the environment but nothing was known of their ability to adapt to weightlessness. At the same time spiders were weaving webs in Earth orbit, similar spiders were spinning webs in identical boxes on Earth under full gravity conditions. Miles was among the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  12. Miles Discusses Experiment With NASA Personnel

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Lexington, Massachusetts high school student, Judith Miles, discusses her proposed Skylab experiment with Keith Demorest (right) and Henry Floyd, both of Marshall Space Flight Center (MSFC). In her experiment, called the 'Web Formation in Zero Gravity', called for spiders to be released into a box and their actions recorded to determine how well they adapt to the absence of gravity. Spiders are known to adapt quickly to other changes in the environment but nothing was known of their ability to adapt to weightlessness. At the same time spiders were weaving webs in Earth orbit, similar spiders were spinning webs in identical boxes on Earth under full gravity conditions. Miles was among the 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab Mission. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of equipment.

  13. Indigenous healing practice: ayahuasca. Opening a discussion.

    PubMed

    Prue, Robert; Voss, Richard W

    2014-01-01

    This essay frames an invitation to pastoral counselors and pastoral theologians to examine connections and perhaps interactions between themselves and traditional shamanic healers who use ayahuasca in their healing ceremonies. Indigenous people in South America have used ayahuasca for centuries, and the ritual has become common among the mestizo populations in urban areas of the Amazon, particularly as a curing ritual for drug addiction (Dobkin de Rios, 1970; Moir, 1998). Like peyote in the United States (Calabrese, 1997) ayahuasca use amongst the indigenous people of the Amazon is a form of cultural psychiatry. A review of the literature reveals very little commentary or discussion of shamanic practice in Pastoral Counseling (Pastoral Theology). The scant literature identifies an antithetical relationship at best. The current authors wonder about the possibility of to including shamanic practices in the context of pastoral counseling? This essay seeks to provide some basic information about the ritual use of ayahuasca and to offer a rationale for pastoral counselors to engage in a dialogue about its utility.

  14. Expert Discussion on Taking a Spiritual History.

    PubMed

    Paal, Piret; Frick, Eckhard; Roser, Traugott; Jobin, Guy

    2017-01-01

    This article elaborates on the hazards of spiritual history taking. It provides expert insights to consider before entering the field. In summer 2012, a group of spiritual care experts were invited to discuss the complexity of taking spiritual histories in a manner of hermeneutic circle. Thematic analysis was applied to define the emerging themes. The results demonstrate that taking a spiritual history is a complex and challenging task, requiring a number of personal qualities of the interviewer, such as 'being present', 'not only hearing, but listening', 'understanding the message beyond the words uttered', and 'picking up the words to respond'. To 'establish a link of sharing', the interviewer is expected 'to go beyond the ethical stance of neutrality'. The latter may cause several dilemmas, such as 'fear of causing more problems', 'not daring to take it further', and above all, 'being ambivalent about one's role'. Interviewer has to be careful in terms of the 'patient's vulnerability'. To avoid causing harm, it is essential to propose 'a follow-up contract' that allows responding to 'patient's yearning for genuine care'. These findings combined with available literature suggest that the quality of spiritual history taking will remain poor unless the health-care professionals revise the meaning of spirituality and the art of caring on individual level.

  15. Online discussions mirroring family life during pregnancy.

    PubMed

    Kouri, Pirkko; Turunen, Hannele; Tossavainen, Kerttu; Saarikoski, Seppo

    2006-01-01

    The aim of this study was to find out what aspects of their parenthood parents revealed, and how they expressed their thoughts concerning maternity care services on an online communication forum. The 'Information Society' offers a growing variety of health services as part of public primary health care via the internet. Little is known about the contents produced online by pregnant families, and how they reflect on both family life and maternity care services. The data for this study were obtained from online discussions between families (n=21) in Net Clinic, an internet-based service designed for public maternity care. The data included experiences of family life during pregnancy, childbirth and parenting, and was analysed by inductive content analysis. While maturing into parenthood, both women and men recognised the uniqueness of their new role and wanted to prepare for safe childbirth. Online communication in the home environment nourished new social networks among families who were expecting their first, second or third child. In addition, families reflected on maternity care services on the Net Clinic's communication forum. This provided realistic feedback to maternity care professionals. Today, the relationship between clients and professionals is inevitably changing. More online services and advocacy are needed if families are to have access to online health services. The role of professionals is diversifying from being authorities to supporting and facilitating clients' individual self-care. Based on direct client feedback, the quality of maternity care can be improved.

  16. Improving Discussion in Astronomy Courses Taught Online

    NASA Astrophysics Data System (ADS)

    Troischt, Parker

    2017-06-01

    Astronomy courses that are either hybrid in nature or offered in a completely online format are becoming more common at colleges and universities. In particular, faculty members at small colleges are being encouraged to develop courses that can be taught online in order to give students increased flexibility in scheduling classes and reach a separate population of learners. For instructors accustomed to teaching students in person using plenty of interaction, making the switch to teaching even one online course a year can be challenging. However, some topics are developing so rapidly (exoplanets) that it is difficult to imagine having students rely on a standard textbook at all, and the use of online resources become essential. Here, we describe methods used to promote discussion, evaluate its content and effectively incorporate the use of recently released articles in order to keep students engaged. We present efforts to produce a lively classroom atmosphere centered on recent advances and several debated topics. Lastly, we report on successes, challenges and plans for improving online courses in the future.

  17. Discussion on ``Foundations of the Second Law''

    NASA Astrophysics Data System (ADS)

    Silbey, Robert; Ao, Ping; Beretta, Gian Paolo; Cengel, Yunus; Foley, Andrew; Freedman, Steven; Graeff, Roderich; Keck, James C.; Lloyd, Seth; Maroney, Owen; Nieuwenhuizen, Theodorus M.; Weissman, Michael

    2008-08-01

    This article reports an open discussion that took place during the Keenan Symposium "Meeting the Entropy Challenge" (held in Cambridge, Massachusetts, on October 4, 2007) following the short presentations—each reported as a separate article in the present volume—by Seth Lloyd, Owen Maroney, Silviu Guiasu, Ping Ao, Jochen Gemmer, Bernard Guy, Gian Paolo Beretta, Speranta Gheorghiu-Svirschevski, and Dorion Sagan. All panelists and the audience were asked to address the following questions • Why is the second law true? Is it an inviolable law of nature? If not, is it possible to develop a perpetual motion machine of the second kind? • Are second law limitations objective or subjective, real or apparent, due to the nature of physical states or the representation and manipulation of information? Is entropy a physical property in the same sense as energy is universally understood to be an intrinsic property of matter? • Does the second law conflict with quantum mechanics? Are the differences between mechanical and thermodynamic descriptions of physical phenomena reconcilable? Does the reversible law of motion of hamiltonian mechanics and quantum mechanics conflict with the empirical observation of irreversible phenomena?

  18. Modelisation de la diffusion sur les surfaces metalliques: De l'adatome aux processus de croissance

    NASA Astrophysics Data System (ADS)

    Boisvert, Ghyslain

    Cette these est consacree a l'etude des processus de diffusion en surface dans le but ultime de comprendre, et de modeliser, la croissance d'une couche mince. L'importance de bien mai triser la croissance est primordiale compte tenu de son role dans la miniaturisation des circuits electroniques. Nous etudions ici les surface des metaux nobles et de ceux de la fin de la serie de transition. Dans un premier temps, nous nous interessons a la diffusion d'un simple adatome sur une surface metallique. Nous avons, entre autres, mis en evidence l'apparition d'une correlation entre evenements successifs lorsque la temperature est comparable a la barriere de diffusion, i.e., la diffusion ne peut pas etre associee a une marche aleatoire. Nous proposons un modele phenomenologique simple qui reproduit bien les resultats des simulations. Ces calculs nous ont aussi permis de montrer que la diffusion obeit a la loi de Meyer-Neldel. Cette loi stipule que, pour un processus active, le prefacteur augmente exponentiellement avec la barriere. En plus, ce travail permet de clarifier l'origine physique de cette loi. En comparant les resultats dynamiques aux resultats statiques, on se rend compte que la barriere extraite des calculs dynamiques est essentiellement la meme que celle obtenue par une approche statique, beaucoup plus simple. On peut donc obtenir cette barriere a l'aide de methodes plus precises, i.e., ab initio, comme la theorie de la fonctionnelle de la densite, qui sont aussi malheureusement beaucoup plus lourdes. C'est ce que nous avons fait pour plusieurs systemes metalliques. Nos resultats avec cette derniere approche se comparent tres bien aux resultats experimentaux. Nous nous sommes attardes plus longuement a la surface (111) du platine. Cette surface regorge de particularites interessantes, comme la forme d'equilibre non-hexagonale des i lots et deux sites d'adsorption differents pour l'adatome. De plus, des calculs ab initio precedents n'ont pas reussi a confirmer la

  19. Nocardiose pulmonaire sur un terrain immunocompétent: à propos de 2 cas

    PubMed Central

    Rhofir, Yasmina; Zahraoui, Rachida; Tiress, Nabil; Naji-Amrani, Hicham; Soualhi, Mouna; Bourkadi, Jamal Eddine

    2017-01-01

    La nocardiose est une infection rare, mais sévère, causée par des bactéries du genre nocardia, qui appartiennent à l'ordre des actinomycétales. Si elles peuvent toucher l'adulte immunocompétent, les nocardioses restent des pathologies de l'individu fragilisé sur le plan immunitaire. L'atteinte pulmonaire reste la plus fréquente, sa prise en charge correcte est liée au diagnostic qui est souvent retardé par des présentations non spécifiques et des prélèvements non concluants. Nous rapportons ici deux cas de nocardiose chez des patients immunocompétents. Le premier cas est celui d'un homme de 24 ans, avec notion de tabagisme et d'éthylisme, hospitalisé pour des douleurs thoraciques et des hémoptysies de faible abondance, évoluant depuis deux mois, avec apparition d'abcès sous cutanés dorsaux fistulisés. L'exploration radiologique découvre une masse tissulaire médiastino-pulmonaire droite avec lyse costale adjacente et diffusion aux tissus para vertébraux droits. Les prélèvements bactériologiques restent négatifs motivant une biopsie scannoguidée de la lésion qui est revenue en faveur d'infection à nocardiose. Le second cas concerne un homme de 22 ans, aux antécédents de tuberculose pleurale traitée il y a 8 ans puis une rechute de tuberculose en 2011 (abcès médiastinal). Admis pour suspicion de rechute de tuberculose devant une toux chronique avec altération de l'état général et une hépatosplénomégalie. Le scanner thoracique montre des condensations alvéolaires avec pleurésie. Au cours de son hospitalisation, apparition de tuméfactions sous cutanées purulentes dont l'étude bactériologique du pus est revenue en faveur de nocardiose avec une souche résistante à tous les antibiotiques sauf colistine et bactrim. Les auteurs illustrent à travers ces deux observations, les aspects cliniques et radiologiques de nocardiose pulmonaire en mettant le point sur les difficultés diagnostiques et thérapeutiques surtout dans un

  20. A tree-ring reconstruction of past precipitation for Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Díaz, Sara C.; Touchan, Ramzi; Swetnam, Thomas W.

    2001-06-01

    There is great interest in the climatic variability of Baja California and the Sea of Cortes, but long-term information is limited because instrumental climate records begin in the 1940s or 1960s. The first tree-ring chronology of Pinus lagunae was developed from the southern part of the Baja California Peninsula and the chronology is used to reconstruct the history of precipitation variations. A September-July precipitation reconstruction is developed for the period AD 1862-1996 (R=0.71, p<0.0001, n=56, cross-validation=0.68). This reconstruction is used to assess precipitation variability over the past two centuries, including the relationship with ENSO events. The reconstructed precipitation series indicates a long drought period from 1939 to 1958. It also shows that 1983, one of the strongest El Niño events of the 20th century, is the wettest year. El Niño events during the 20th century are associated with above-normal precipitation, whereas La Niña events are characterized by below-normal precipitation. Four of the most extreme wet years occurred in association with these warm events (1905, 1912, 1919 and 1983). Seventy-one percent of La Niña events are characterized by below-normal precipitation. Sixty-two percent of El Niño events are characterized by above-normal precipitation. Tree-ring growth of P. lagunae is most strongly correlated with winter precipitation in Sonora, Sinaloa and southern Baja California Sur. Precipitation data from meteorological stations in northern Baja California do not correlate well with the tree-ring chronology because this zone has a Mediterranean climate, which differs from the rest of northwest Mexico.

  1. Terrain complexity characterization in the eastern coast of Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Martínez Flores, G.; Nava-Sanchez, E. H.; Segovia Zavala, J. A.

    2013-05-01

    Terrain complexity is an important feature for geomorphological analysis and characterization, since it is associated with processes that control the landscape evolution, giving rise to geological formations of varying topographic complexity. In the geometrical sense, the terrain complexity depicts the shape of the landform surface or cross section, such as rugosity, curvature, fractal dimension, slope, aspect, etc. Moreover, the coastline complexity or indentation index has been used as an auxiliary parameter in coastline characterization. Currently, there are a variety of terrain and shoreline complexity indexes, derived from digital elevation models and digital coastlines, respectively, which usually are evaluated and interpreted independently. In this work the evaluation of these indexes was implemented in twenty watersheds of the eastern coast of the Mexican state of Baja California Sur. To evaluate the terrain complexity index, the slope, profile curvature and roughness were computed and weighted. For this purpose the digital elevation model of 30 m resolution, obtained from the National Institute of Statistics and Geography (INEGI) was used. The coastline complexity was assessed based on the variability of angles of coastline segments, as are defined in the Global Self-consistent, Hierarchical, High-resolution Geography Database (GSHHG). Five classes were identified for each index, whose distribution was represented by digital cartography. In general, the gullies have the highest terrain complexity, while the lower values correspond to areas of alluvial fans and other areas of sedimentation close to the shoreline. The spatial distribution of these indexes could be useful to mapping terrain classification and as support to analyze geological and oceanographic processes that influence this region.

  2. Stratigraphy of Pyroclastic Deposits of EL Aguajito Caldera, Baja California Sur, MÉXICO

    NASA Astrophysics Data System (ADS)

    Osorio Ocampo, L. S.; Macias, J. L.; García Sánchez, L.; Pola, A.; Saucedo, R.; Sánchez, J. M.; Avellán, D. R.; Cardona, S.; Reyes-Agustín, G.; Arce, J. L.

    2015-12-01

    El Aguajito caldera is located in the State of Baja California Sur, it comprises an area of 450 km2 and sits within the Santa Rosalía Basin which is controlled by NE-SW extensional structures and the NW-SE Cimarron Fault that transects the caldera structure. The oldest rocks are ~90 Ma granodiorites covered by an Oligocene-Miocene volcano-sedimentary sequence, the Miocene Santa Lucia Formation and La Esperanza basalt. Pliocene volcanism is represented by La Reforma caldera, El Aguajito caldera, and the Tres Vírgenes Volcanic complex. This study focuses on the cartography and stratigraphy of area in order to understand the evolution of the volcanic system. The stratigraphy from base to top consists of a series of shallow marine sediments (fossiliferous sandstones) covered by a thick sequence of ignimbrites and pyroclastic flows interbedded with volcaniclastic deposits (Gloria and El Infierno Formations). On top of these deposits is El Aguajito caldera, it consists of a 2 m thick pumice fallout followed by an ignimbrite with three transitional lithofacies: a ≤30-m thick light-pink pyroclastic flow enriched in pumice at the base that gradually becomes enrich in lithics towards the top with the occurrence of degasing pipes. On top rests a 15 m-thick light-purple ignimbrite slightly welded with fiammes and a sequence of pumiceous pyroclastic flows and fallouts. These deposits have been associate to the caldera formation with a collapse diameter of ~8 km marked by rhyolitic domes exposed along a ring collapse crowned the sequence as well as NW-SE aligned rhyolitic domes parallel to the seashore. This cartography allowed to present a preliminary new geological map with four stratigraphic units recognized so far, that were emplaced under subaerial conditions beginning with a Plinian column followed by the emplacement of El Aguajito ignimbrite with its subsequent caldera collapse and finally the extrusion of resurgent domes.

  3. Availability of safe drinking-water: the answer to cholera outbreak? Nabua, Camarines Sur, Philippines, 2012.

    PubMed

    De Guzman, Alethea; de los Reyes, Vikki Carr; Sucaldito, Ma Nemia; Tayag, Enrique

    2015-01-01

    In May 2012, there were increasing diarrhoea cases and deaths reported from Nabua, Camarines Sur to the Philippines event-based surveillance system. An investigation was conducted to identify risk factors and determine transmission dynamics. A suspected case was defined as a resident of Nabua with at least three episodes of watery diarrhoea per day from 16 March to 22 June 2012. A confirmed case was defined as a suspected case positive for Vibrio cholerae. An environmental investigation was conducted and rectal swabs and water samples sent to the national reference laboratory for bacterial isolation. A 1:2 case-control study matching for age and sex was conducted. Data were analysed using Epi Info. There were 309 suspected cases with two deaths, and the most affected age group was children under five years (45%). Eight cases were positive for Vibrio cholerae Ogawa El Tor and one for Non-01. Water samples were positive for faecal coliforms and Aeromonas caviae. The case-control study showed that cases had a higher odds than controls of using unchlorinated water sources (odds ratio [OR] = 3.6; 95% confidence interval [CI]:1.6-8.5) and having toilets located within 20 m of a septic tank (OR = 2.7; 95% CI: 1.4-5.3). In multivariate analysis, the only significant factor was drinking from piped water (OR = 0.21; 95% CI: 0.09-0.49). In this cholera outbreak, drinking-water from unchlorinated wells was a significant risk factor. Future cholera control efforts should include not just improving water and sanitation systems but also intensified behaviour change campaigns.

  4. Europe discusses role in future space telescope

    NASA Astrophysics Data System (ADS)

    1998-06-01

    Prof. Roger Bonnet said it was important for Europe to make an informed decision in the next few years on whether to support NASA's proposed New Generation Space Telescope (NGST), a follow-on programme to the Hubble Space Telescope. NGST's observing capabilities will far extend the reach of existing ground or space-based telescopes, providing the opportunity for the first time to look back through eons of time to the very first stars and galaxies in the Universe. With an aperture greater than four metres, NGST could also provide European astronomers with a crucial complement to some of ESA's planned future space projects, like FIRST (the Far InfraRed Submillimetre Telescope) and Planck (a mission to study the cosmic background radiation field). NASA and ESA are already involved in preliminary NGST studies but Europe has yet to make a commitment to support the programme. NASA wants to start formal development in 2003, with a launch currently planned for 2007. This week's conference at Liege in Belgium was the first opportunity for many astronomers to exchange ideas and compare technological notes on a Next Generation Space Telescope. It also provided a forum for representatives of Europe's space industry to discuss the technological challenges presented by such a project. Prof. Bonnet said: "From recent experience it is clear that the best scientific results in astronomy and astrophysics are obtained by coordinated observations in different wavelength ranges. "The joint effort of the European space programme and of the various large European ground observatories currently allows European astronomers to be on the front-line of astrophysics research."He said that ESA - if supported programmatically and financially by its member states - is willing to discuss with NASA a mutually fruitful form of NGST participation. But Prof. Bonnet stressed that for this type of collaboration to be approved it remained crucial that the European share contained both scientific and

  5. Simulation de l'accretion de glace sur un obstacle bidimensionnel par la methode des bissectrices et par la modelisation des ruisselets et des gouttes de surface

    NASA Astrophysics Data System (ADS)

    Fortin, Guy

    Le LIMA (Laboratoire International des Materiaux Antigivre) en collaboration avec le CIRA (Italian Aerospace Research Centre) a developpe un logiciel simulant l'accretion de la glace en regimes sec et humide sur un objet bidimensionnel fixe. L'approche utilisee s'appuie sur les travaux de Lozowski pour les bilans energetiques, sur une etude du comportement du film d'eau, des ruisselets et des gouttes de surface pour le calcul des rugosites et des masses d'eau residuelle, ainsi que sur une methode de bissectrice pour l'evolution de la surface de glace. La contribution du CIRA a ete de fournir le logiciel pour le calcul des ecoulements et de la captation. Le bilan energetique base sur la conservation de l'energie est la sommation de la chaleur latente de fusion, d'evaporation et de sublimation, du rechauffement adiabatique et cinetique, et des pertes de chaleur par convection et conduction, ainsi que de l'evolution thermodynamique de l'eau de son etat initial a son etat final. La densite de la glace, qui a un impact important sur la simulation, est calculee a partir d'une correlation empirique developpee avec les cylindres tournants. En se basant sur les travaux de Al-Khalil et Hansman, le comportement des gouttes en regimes sec et humide a ete decrit analytiquement, ce qui a mene a determiner la hauteur maximale que peuvent atteindre les gouttes avant mouvement. Cette hauteur, appelee hauteur de mouvement, permet de determiner l'etat de l'eau sur la surface (film, ruisselets ou gouttes), ainsi que la hauteur des rugosites lorsque l'eau existe sous forme de gouttes ou de ruisselets. La hauteur de mouvement est determinee par l'equilibre entre les forces de cisaillement, induites par les effets aerodynamiques et gravitationnels evalues pour une goutte non deformee, et la force de cisaillement, induite par la tension de surface et la deformation de la goutte. Elle a ete validee en laboratoire et la precision obtenue pour la partie aerodynamique et gravitationnelle est

  6. Water, food, and population -- a panel discussion.

    PubMed

    1996-01-01

    This paper summarizes a conference panel discussion among parliamentarians and researchers on water and food supplies and population growth in Asia. The Western Samoa legislator urged delegates to be aware of human development that was no more than the promotion of values associated with a market economy. Samoans increased their per capita caloric consumption. The food supply is provided locally, and 90% of exports are food products. Food security would be jeopardized by a fivefold increase in population. Samoan human development indicators were relatively good for a developing country. However, the country was still ranked as a low-income, food-deficit country. The Pakistani delegate explained that Pakistan's agriculture used the largest, continuous irrigation system in the world. However, the system operated inefficiently. There was concern that future high population growth would jeopardize food security. Another barrier was institutional mismanagement of irrigation and reliance on imports for staple items. Agricultural productivity must increase to meet the increased needs of continued population growth. All available land is currently under cultivation. Future strategies will necessitate international cooperation and innovative and environmentally sound technology. Professor Xuan remarked that increased population growth and rising demand, decreased water quality, and changing consumption patterns were a threat to water supplies. Sustainable increases in food production would entail better water management: reforestation to reduce and prevent water runoff, better technological exploitation of rain water, and more efficient use of irrigation systems. Better international financing schemes were needed for support of these policy changes. Professor Ness suggested free markets in water in order to price water at actual rates of consumption. Polluters should pay. Water management was also threatened by global warming.

  7. Bioethics and multiculturalism: nuancing the discussion.

    PubMed

    Durante, Chris

    2017-08-11

    In his recent analysis of multiculturalism, Tom Beauchamp has argued that those who implement multicultural reasoning in their arguments against common morality theories, such as his own, have failed to understand that multiculturalism is neither a form of moral pluralism nor ethical relativism but is rather a universalistic moral theory in its own right. Beauchamp's position is indeed on the right track in that multiculturalists do not consider themselves ethical relativists. Yet, Beauchamp tends to miss the mark when he argues that multiculturalism is in effect a school of thought that endorses a form of moral universalism that is akin to his own vision of a common morality. As a supporter of multiculturalism, I would like to discuss some aspects of Beauchamp's comments on multiculturalism and clarify what a multicultural account of public bioethics might look like. Ultimately, multiculturalism is purported as a means of managing diversity in the public arena and should not be thought of as endorsing either a version of moral relativism or a universal morality. By simultaneously refraining from the promotion of a comprehensive common moral system while it attempts to avoid a collapse into relativism, multiculturalism can serve as the ethico-political framework in which diverse moralities can be managed and in which opportunities for ethical dialogue, debate and deliberation on the prospects of common bioethical norms are made possible. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Effet de l'etat de la surface de l'acier au carbone 300W sur l'entartrage par la gibbsite dans le procede Bayer

    NASA Astrophysics Data System (ADS)

    Gavril, Liliana

    Une etude a ete effectuee sur l'entartrage des surfaces en acier au carbone par la gibbsite dans le procede Bayer. Trois methodes ont ete utilisees afin de determiner le mecanisme de formation du tartre: mesure de la vitesse d'entartrage, etude electrochimique et protection cathodique. Cette etude demontre que le tartre de gibbsite est un tartre de cristallisation et que l'etat physico-chimique de la surface metallique a une influence marquee sur l'entartrage. Ainsi, l'oxyde en surface a ete identifie comme un facteur determinant pour l'entartrage. Les essais electrochimiques ont montre que la couche d'oxyde formee dans les solutions Bayer est un oxyde mixte de fer et d'aluminium. Les essais de protection cathodique a courant constant valident le role determinant joue par l'oxyde sur l'entartrage, puisqu'en empechant l'oxyde de se former, l'entartrage est pratiquement elimine. Le mecanisme d'adherence du tartre a l'acier implique trois etapes, soit l'oxydation du metal, la formation de la goethite/goethite alumineuse sur l'oxyde et finalement, la germination de la gibbsite sur la goethite/goethite alumineuse.

  9. Comparison of outcomes for cancer patients discussed and not discussed at a multidisciplinary meeting.

    PubMed

    Rogers, M J; Matheson, L; Garrard, B; Maher, B; Cowdery, S; Luo, W; Reed, M; Riches, S; Pitson, G; Ashley, D M

    2017-08-01

    Comparison of outcomes for cancer patients discussed and not discussed at a multidisciplinary meeting (MDM). Retrospective analysis of the association of MDM discussion with survival. All newly diagnosed cancer patients from 2009 to 2012, presenting to a large regional cancer service in South West Victoria, Australia (620 colorectal, 657 breast, 593 lung and 511 haematological) were recorded and followed up to 5 years after diagnosis. Treatment patterns and survival of patients whose treatment was discussed at an MDM compared to those who were not, were explored. The proportion of patients presented to an MDM within 60 days after diagnosis was 56% (n = 366) for breast cancer, 59% (n = 363) for colorectal cancer, 27% (n = 137) for haematological malignancies and 60% (n = 355) for lung cancer. Seventy-three percent (n = 886) of patients discussed at an MDM had their tumour stage recorded in their medical records while only 52% (n = 604) of patients not discussed had their tumour stage recorded (P < 0.01). We found for haematological and lung cancer patients that those presented to an MDM prior to treatment had a significant reduction in mortality (lung cancer hazard ratio [HR] 0.62, 95% confidence interval [CI] 0.50-0.76, P < 0.01) (haematological cancer HR 0.58, 95% CI 0.35-0.96, P = 0.03) compared to patients whose cases were not discussed at an MDM after adjusting for the potential cofounders of age, stage, comorbidities and treatment. This was not the case for colorectal and breast cancer patients where there was no significant difference. MDM discussion has been recommended as best practice in the management of cancer patients, however, from a public health perspective this creates potential issues around access and resources. It is likely that MDM presentation patterns and outcomes across tumour streams are linked in complex ways. We believe that our data would demonstrate that these patterns differ across tumour streams and that more detailed

  10. Current Discussions Between ESO and Chile

    NASA Astrophysics Data System (ADS)

    1995-04-01

    [Joint Press Release by the Government of the Republic of Chile and the European Southern Observatory. The text is issued simultaneously in Santiago de Chile (in Spanish) and at the ESO Headquarters in Garching (in English).] Today, Tuesday, 18 April 1995, at the ESO Headquarters in Garching (Germany), Mr. Roberto Cifuentes, Plenipotentiary Ambassador representing the Government of the Republic of Chile, and the Director General of the European Southern Observatory, Professor Riccardo Giacconi, have signed a Supplementary, Interpretative and Amending Agreement to the Convention of 6 November 1963 which governs the relations between Chile and this International Organisation. This Agreement which in practice signifies a widening and strengthening of the cooperative relations between the Organisation and the Chilean scientific community will hereafter be submitted for ratification by the National Congress of the Republic of Chile (the Parliament) and by the ESO Council. According to the Agreement signed today, Chilean astronomers will have privileged access within up to 10 percent observing time on all present and future ESO telescopes in Chile. Moreover, ESO accepts to incorporate into its labour regulations for Chilean personnel concepts like freedom of association and collective bargaining. This signing of the Supplementary, Interpretative and Amending Agreement to the original Convention of 1963 follows after months of constructive dialogue between the parties. It constitutes an important step towards a solution of some of the pending points on the current agenda for discussions between the Government of Chile and ESO. Among the issues still pending, ESO has informed the Government of Chile that respect for its immunities by the Chilean State is of vital importance for the continuation of the construction of the world's largest telescope at Paranal, as well as the continued presence of the Organisation in Chile. The Chilean Government, on its side, and concerning

  11. The Impact of Online Discussion on Face-to-Face Discussion and Academic Achievement

    ERIC Educational Resources Information Center

    Yu, Serena W.

    2009-01-01

    The purpose of this study was to research the effects of online discussion on face-to-face (F2F) classroom participation and academic achievement for 18 public high school students in a senior English class. The teacher used a variety of data collection including surveys, test scores, journal reflections, and teacher observations to study the…

  12. Discussing Ethical Issues in the Classroom: Leveraging Pedagogical Moments that May Otherwise Undermine Important Discussions

    ERIC Educational Resources Information Center

    Simpson, Douglas J.; Hull, William J., Jr.

    2011-01-01

    The authors identify, examine, and clarify three kinds of hindrances (dismissive/evasive tactics, logical stoppers, and ad hominem arguments) to teaching about ethical issues in P-12 schools. In discussing these three types of obstacles, they stress that the barriers themselves provide both challenges and opportunities for teachers. Indeed, they…

  13. Prediction de l’Eclatement Tourbillonnaire sur les Ailes Delta d’Avions Militaires (CFD Prediction of Vortex Breakdown on Delta Wings for Military Aircraft)

    DTIC Science & Technology

    2003-03-01

    contrôle spécifiques. Une première étape dans ce genre d’étude est de s’assurer que l’on peut simuler déjà de façon précise l’éclatement...tourbillonnaire sur une aile delta en l’absence de dispositif de contrôle . Dassault Aviation a réalisé des calculs (Euler et Navier-Stokes) sur la configuration...expérience Communication présentée lors du symposium RTO AVT sur «La gestion avancée des écoulements : Partie A – Les écoulements tourbillonnaires et les

  14. Lambeau Expanse du Cuir Chevelu dans la Couverture des Alopecies Cicatricielles sur Sequelles de Brulures. A Propos d'une Observation

    PubMed Central

    El Mazouz, S.; Hafidi, J.; Fejjal, N.; Mejjati, H.; Cherkab, L.; Gharib, N.; Abbassi, A.

    2010-01-01

    Summary Les séquelles esthétiques des alopécies cicatricielles sur séquelles de brûlures sont responsables de préjudices empêchant parfois la réinsertion sociale du patient, surtout chez les sujets de sexe féminin. Le cuir chevelu permet la réalisation de lambeaux permettant de couvrir ces alopécies. Les Auteurs décrivent le cas d'une jeune patiente victime d'une alopécie cicatricielle sur séquelles de brûlures chez qui ils ont réalisé un lambeau expansé du cuir chevelu et mettent le point sur la prise en charge de ces lésions à travers ce cas clinique et une revue de littérature. PMID:21991195

  15. General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG.

    PubMed

    Proudfoot, Michael; Kuznetsova, Ekaterina; Brown, Greg; Rao, Narayana N; Kitagawa, Masanari; Mori, Hirotada; Savchenko, Alexei; Yakunin, Alexander F

    2004-12-24

    To find proteins with nucleotidase activity in Escherichia coli, purified unknown proteins were screened for the presence of phosphatase activity using the general phosphatase substrate p-nitrophenyl phosphate. Proteins exhibiting catalytic activity were then assayed for nucleotidase activity against various nucleotides. These screens identified the presence of nucleotidase activity in three uncharacterized E. coli proteins, SurE, YfbR, and YjjG, that belong to different enzyme superfamilies: SurE-like family, HD domain family (YfbR), and haloacid dehalogenase (HAD)-like superfamily (YjjG). The phosphatase activity of these proteins had a neutral pH optimum (pH 7.0-8.0) and was strictly dependent on the presence of divalent metal cations (SurE: Mn(2+) > Co(2+) > Ni(2+) > Mg(2+); YfbR: Co(2+) > Mn(2+) > Cu(2+); YjjG: Mg(2+) > Mn(2+) > Co(2+)). Further biochemical characterization of SurE revealed that it has a broad substrate specificity and can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. SurE also hydrolyzed polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P(20-25)). YfbR was strictly specific to deoxyribonucleoside 5'-monophosphates, whereas YjjG showed narrow specificity to 5'-dTMP, 5'-dUMP, and 5'-UMP. The three enzymes also exhibited different sensitivities to inhibition by various nucleoside di- and triphosphates: YfbR was equally sensitive to both di- and triphosphates, SurE was inhibited only by triphosphates, and YjjG was insensitive to these effectors. The differences in their sensitivities to nucleotides and their varied substrate specificities suggest that these enzymes play unique functions in the intracellular nucleotide metabolism in E. coli.

  16. Evaluation of the PSAMAO "Roulez Protégé" mass media campaign in Burkina Faso. Prévention du SIDA sur les Axes Migratoires de l'Afrique de l'Ouest.

    PubMed

    Tambashe, B Oleko; Speizer, Ilene S; Amouzou, Agbessi; Djangone, A M Rachelle

    2003-02-01

    This study assesses the impact of the Prevention du SIDA sur les Axes Migratoires de l'Afrique de l'Ouest Roulez Protege mass media campaign in Burkina Faso on truckers' likelihood of talking with colleagues about HIV/AIDS, using condoms with an occasional sexual partner, and intending to use a condom in the future. A total of 764 and 1,032 truckers were interviewed in 1997 and 2000 along the Ouagadougou-Niangoloko trucking route. Truckers' exposure to the program has been high and the main message promoted has been greatly understood among those exposed. Logistic regression analyses suggest that the campaign did not have direct behavioral impacts. Exposure to radio spots and participation in group discussions were found to be significantly associated with truckers discussing AIDS with peers or reporting intentions to use a condom in the future. Exposure to Roulez Protege messages through television or billboards was not found to be significantly associated with interpersonal discussion or condom use intentions. Programs should seek to sustain and expand the indirect effects of these types of programs in West Africa. Reinforcing interpersonal counseling interventions should, down the road, lead to overall knowledge and behavior changes among the high-risk trucker population.

  17. Geochemistry of a Tertiary sedimentary phosphate deposit: Baja California Sur, Mexico

    USGS Publications Warehouse

    Piper, D.Z.

    1991-01-01

    The San Gregorio Formation in Baja California Sur, a phosphate-enriched sedimentary unit of late Oligocene to early Miocene age, has been analyzed in two areas (La Purisima and San Hilario) for its chemical composition (major oxides, Cu, Cd, Cr, Co, V, and rare-earth elements - REE) and isotopic composition (??18O and ??13C). A detrital and a marine component were determined from major oxides. The detrital component consists of an unaltered volcanic-ash fraction and a terrigenous clay-silt fraction. The marine component, which accumulated initially as biogenic and hydrogenous material, is now present as opal-A, opal-CT, CaCO3, organic matter, and an authigenic phosphate fraction, mostly pelletal and composed of the carbonate-fluorapatite mineral francolite. The minor elements have been partitioned into these components by assuming a constant composition for the two detrital fractions. The composition of the marine component of minor elements can then be interpreted by assuming that the stoichiometry of the original accumulating organic matter was equal to that of modern plankton. The Cu and Cd contents in the marine component of all rocks require that the seawater-derived fractions of these two metals were supplied to the seafloor solely by organic matter. Enrichments of Cr and V at both sites required an additional marine input. On the basis of their geochemistry in the modern ocean, Cr and V could have precipitated, or been adsorbed, onto settling particles from an O2 minimum zone in which the O2 content was low enough to promote denitrification rather than oxygen respiration. An enrichment of the REE, now within the apatite fraction, resulted from their adsorption onto particulates also in the O2 minimum zone and to the dissolution and alteration of biogenic phases (predominantly silica) within the sediment. Co and Fe2O3 show no enrichment above a detrital contribution. The ??18O-values of apatites from the La Purisima site are heavier than those of apatites

  18. Challenges and opportunities for implementing sustainable energy strategies in coastal communities of Baja California Sur, Mexico

    NASA Astrophysics Data System (ADS)

    Etcheverry, Jose R.

    This dissertation explores the potential of renewable energy and efficiency strategies to solve the energy challenges faced by the people living in the biosphere reserve of El Vizcaino, which is located in the North Pacific region of the Mexican state of Baja California Sur. This research setting provides a practical analytical milieu to understand better the multiple problems faced by practitioners and agencies trying to implement sustainable energy solutions in Mexico. The thesis starts with a literature review (chapter two) that examines accumulated international experience regarding the development of renewable energy projects as a prelude to identifying the most salient implementation barriers impeding this type of initiatives. Two particularly salient findings from the literature review include the importance of considering gender issues in energy analysis and the value of using participatory research methods. These findings informed fieldwork design and the analytical framework of the dissertation. Chapter three surveys electricity generation as well as residential and commercial electricity use in nine coastal communities located in El Vizcaino. Chapter three summarizes the fieldwork methodology used, which relies on a mix of qualitative and quantitative research methods that aim at enabling a gender-disaggregated analysis to describe more accurately local energy uses, needs, and barriers. Chapter four describes the current plans of the state government, which are focused in expanding one of the state's diesel-powered electricity grids to El Vizcaino. The Chapter also examines the potential for replacing diesel generators with a combination of renewable energy systems and efficiency measures in the coastal communities sampled. Chapter five analyzes strategies to enable the implementation of sustainable energy approaches in El Vizcaino. Chapter five highlights several international examples that could be useful to inform organizational changes at the federal

  19. Le cancer en Mauritanie : résultats sur 10 ans du registre hospitalier de Nouakchott

    PubMed Central

    Baba, Nacer Dine Ould Mohamed; Sauvaget, Catherine

    2013-01-01

    Le fardeau du cancer reste mal connu en Mauritanie. Il n'est basé que sur des extrapolations de l'incidence des cancers des pays avoisinants. Les données du registre de l'hôpital national permettent de décrire les cas avec un diagnostic histologique. Tous les cas de cancers enregistrés par le service d'anatomo-pathologie de l'hôpital national de Nouakchott de 2000 à 2009 ont été analysés. En 10 ans, 3305 prélèvements histologiques ont été analysés (hommes:42%, femmes:58%). Chez l'homme, le cancer le plus fréquemment analysé était le cancer de la peau (218 cas au total, 189 cas en excluant mélanome), suivi de la prostate (203), des cancers digestifs (179, colorectal et ‘sophage), et des lymphomes (151). Chez la femme, un quart des biopsies était des cancers du sein (485), suivi du col utérin (344), de la sphère gynécologique (218, ovaire et corps utérin), et de la peau (114). Les cancers du foie, du poumon ou de la vessie étaient peu fréquents. Ces résultats ne reflètent pas l'incidence ni l'actuel fardeau du cancer en Mauritanie puisque de nombreux patients diagnostiqués avec un cancer ne reçoivent pas d'examen anatomopathologique. Si, comme dans les pays avoisinants du Maroc et du Mali, les cancers du col et du sein sont les pathologies les plus fréquentes chez la femme, la distribution des cancers chez l'homme dans ce registre hospitalier diffère des résultats des registres de population du Maroc et du Mali où les cancers du poumon, du foie, de la prostate et de la vessie dominent. PMID:23785554

  20. Syndrome de Sweet: étude clinique et natomopathologique sur 5 ans

    PubMed Central

    Bouzidi, Hanae; Gallouj, Salim; Amraoui, Nissrine; Mernissi, Fatima Zahra; Harmouch, Taoufiq

    2015-01-01

    Le syndrome de Sweet ou dermatose aiguë fébrile neutrophilique est une maladie inflammatoire rare à expression cutanée prédominante, appartenant au groupe des dermatoses neutrophiliques. Il est caractérisé par le polymorphisme de son expression clinique et la diversité des maladies qui peuvent lui être associées. Le but de ce travail était d’étudier les particularités cliniques, anatomopathologiques, thérapeutiques et évolutives du syndrome de Sweet. Nous rapportons une étude rétrospective et descriptive de 25 cas de syndrome de Sweet observés dans les services de dermatologie et d'anatomie pathologique du centre hospitalier universitaire de Fès sur une période de 5 ans. Notre série était constituée de 5 hommes et de 20 femmes avec un sex-ratio (hommes/femmes) de 0,25. L’âge moyen des patients était de 47 ans avec des extrêmes allant de 11 à 75 ans. Des maladies associées étaient retrouvées chez 17 patients: hémopathies (deux cas), tumeur solide (1cas), maladie chronique de l'intestin (1cas), tuberculose (1 cas), diabète (trois cas) et infections (9 cas). Deux patientes étaient enceintes au moment du diagnostic. Les manifestations cutanées étaient polymorphes avec atteintes muqueuses dans deux cas. Les lésions siégeaient le plus souvent au niveau acral. Histologiquement, le derme était le siège d'un infiltrat dense et diffus riche en polynucléaires neutrophiles dans tous les cas. Une inflammation de la paroi des vaisseaux étaient observées dans trois cas. Le syndrome de Sweet peut être révélateur ou précéder des maladies associées, ce qui impose une surveillance rigoureuse et prolongée. PMID:26185554