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Sample records for 25th 50th 75th

  1. [World War II 50th Anniversary.

    ERIC Educational Resources Information Center

    Johnson, Jeniffer, Ed.

    1991-01-01

    This edition of "Loblolly," a periodical published by Texas high school students, commemorates the 50th anniversary of World War II. The volume features remembrances of the War by veterans of Panola County, Texas. In addition to transcriptions of conversations with veterans, reproductions of photographs--some from the war period, some from more…

  2. 50th JANNAF Propulsion Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Eggleston, Debra S. (Editor)

    2001-01-01

    This volume, the first of two volumes, is a collection of 29 unclassified/unlimited-distribution papers which were presented at the 50th Joint Army-Navy-NASA-Air Force (JANNAF) Propulsion Meeting, held 11-13 July 2001 at the Salt Lake City Marriott Hotel in Salt Lake City, Utah.

  3. ESO 50th Anniversary Gala Dinner

    NASA Astrophysics Data System (ADS)

    Sirey, R.

    2012-12-01

    To formally mark the 50th anniversary of the signing of the ESO Convention, a gala dinner was held in the Munich Residenz. A brief report of the event is presented and the speeches are reproduced. The speakers were the President of the Council, Xavier Barcons; the German Minister for Education and Research, Prof. Dr Annette Schavan; the Bavarian State Minister for Science, Research and the Arts, Dr Wolfgang Heubisch; physics Nobel Laureate, Brian Schmidt; the current Director General, Tim de Zeeuw and the Chilean Minister of Foreign Affairs, Alfredo Moreno Charme.

  4. Apollo 11 25th Anniversary logo

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This Official NASA commemorative logo marks the 25th anniversary of the first lunar landing. The design incorporates an eagle, from the original Apoll 11 crew insignia, descending toward the lunar surface with an olive branch, symbolizing America's peaceful mission in space. Alternative Headquarters number is 93-HC-312 or 93-H-336.

  5. The 50th Annual Maize Genetics Conference

    SciTech Connect

    Cone, Karen

    2014-03-26

    The 50th Annual Maize Genetics Conference was held February 27 - March 2, 2008 at the Marriott Wardman Park Hotel in Washington, D.C. As the golden anniversary of the Conference and coinciding with the release of a draft of the maize genome sequence, this was a special meeting. To publicize this unique occasion, meeting organizers hosted a press conference, which was attended by members of the press representing science and non-science publications, and an evening reception at the Smithsonian National Museum of Natural History, where the draft sequence was announced and awards were presented to Dr. Mary Clutter and Senator Kit Bond to thank them for their outstanding contributions to maize genetics and genomics research. As usual, the Conference provided an invigorating forum for exchange of recent research results in many areas of maize genetics, e.g., cytogenetics, development, molecular genetics, transposable element biology, biochemical genetics, and genomics. Results were shared via both oral and poster presentations. Invited talks were given by four distinguished geneticists: Vicki Chandler, University of Arizona; John Doebley, University of Wisconsin; Susan Wessler, University of Georgia; and Richard Wilson, Washington University. There were 46 short talks and 241 poster presentations. The Conference was attended by over 500 participants. This included a large number of first-time participants in the meeting and an increasingly visible presence by individuals from underrepresented groups. Although we do not have concrete counts, there seem to be more African American, African and Hispanic/Latino attendees coming to the meeting than in years past. In addition, this meeting attracted many participants from outside the U.S. Student participation continues to be hallmark of the spirit of free exchange and cooperation characteristic of the maize genetics community. With the generous support provided by DOE, USDA NSF, and corporate/private donors, organizers were

  6. Hubble 25th Anniversary: NASA Social at Goddard

    NASA Video Gallery

    NASA's Hubble Space Telescope celebrated its 25th anniversary on April 24, 2015. To mark the occasion, NASA's Goddard Space Flight Center in Greenbelt, Maryland -- home of Hubble operations -- host...

  7. EDITORIAL: Inverse Problems' 25th year of publication Inverse Problems' 25th year of publication

    NASA Astrophysics Data System (ADS)

    2008-01-01

    2009 is Inverse Problems' 25th year of publication. In this quarter-century, the journal has established itself as the premier publication venue for inverse problems research. It has matured from its beginnings as a niche journal serving the emerging field of inverse and ill-posed problems to a monthly publication in 2009 covering all aspects of a well-established, vibrant and still-expanding subject. Along with its core readership of pure and applied mathematicians and physicists, Inverse Problems has become widely known across a broad range of researchers in areas such as geophysics, optics, radar, acoustics, communication theory, signal processing and medical imaging, amongst others. The journal's appeal to the inverse problems community and those researchers from the varied fields that encounter such problems can be attributed to our commitment to publishing only the very best papers, and to offering unique services to the community. Besides our regular research papers, which average a remarkably short five months from submission to electronic publication, we regularly publish heavily cited topical review papers and topic-specific special sections, which first appeared in 2004. These highly-downloaded invited articles focus on the latest developments and hot topics in all areas of inverse problems. No other journal in the field offers these features. I am very pleased to take Inverse Problems into its 25th year as Editor-in-Chief. The journal has an impressive tradition of scholarship, established at its inception by the founder and first Editor-in-Chief, Professor Pierre Sabatier. Professor Sabatier envisioned the journal in 1985 as providing a medium for publication of exemplary research in our intrinsically interdisciplinary field. I am glad to say that the support of our authors, readers, referees, Editors-in-Chief, Editorial Boards and Advisory Panels over the years, has resulted in Inverse Problems becoming the top publication in this field, publishing

  8. 76 FR 26923 - 50th Anniversary of the Freedom Rides

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... From the Federal Register Online via the Government Publishing Office ] Vol. 76 Monday, No. 89 May 9, 2011 Part V The President Proclamation 8668--50th Anniversary of the Freedom Rides #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 76, No. 89 / Monday, May 9, 2011 / Presidential Documents#0;#0; #0; #0;Title 3-- #0;The President ]...

  9. 25th anniversary of the Gagarin Cosmonaut Training Center

    NASA Technical Reports Server (NTRS)

    Goreglyad, I.; Shonin, G.

    1985-01-01

    Interviews with retired Major General of Aviation L. Goreglyad and pilot-cosmonaut with the 25th anniversary of the establishment of the Gagarin Cosmonaut Training Center. Major-General Goreglyad, one of the Center's founders, tells of its development. Major General Shonin, one of the first cosmonauts to train there, tells of the tests and procedures leading to his acceptance as a trainee.

  10. The Narrabri Stellar Intensity Interferometer: a 50th birthday tribute

    NASA Astrophysics Data System (ADS)

    Tuthill, Peter G.

    2014-07-01

    This year marks the 50th anniversary since the first scientific measurements were produced with the Narrabri Stellar Intensity Interferometer, which was constructed in the early 1960's by Robert Hanbury Brown and Richard Twiss. A collaboration between the Universities of Sydney and Manchester, the interferometer was the culmination of a series of experiments which pioneered the technique of intensity interferometry. The immediate controversy surrounding the quantum implications of the technique enveloped some of the most eminent physicists of the day, sparking a debate about nonlocal effects and optical coherence. A full explanation of the workings of the intensity interferometer in a quantum context was finally put forward by Roy Glauber, ultimately earning him the 2005 Nobel Prize in Physics. The intensity interferometer rekindled the field of high resolution stellar imaging, which had been extinguished for a half century (following the failure of Pease's 50-foot beam on Mt Wilson), while delivering the first ever measurements of the sizes of normal stars - establishing an effective temperature scaling relationship which has underpinned stellar astronomy for 50 years. This directly paved the way for the next generation of Michelson Stellar Interferometers. Intensity interferometry itself has found application in several fields (notably particle physics), and plans are in active development for modern reprises within stellar interferometry. However undoubtedly the greatest legacy lies in the Hanbury Brown Twiss (HBT) effect being the foundational experiment for what is now known as Quantum Optics - a field which underpins a huge sector of the technology which enables our modern world. This invited review discuses the development of the interferometer, including the controversy that its underlying principles generated within the contemporary physics community. The core scientific output generated by the instrument is presented, together with the impact of the

  11. Army Medical Department Lessons Learned Program marks 25th anniversary.

    PubMed

    Cannon, David W; McCollum, Jeffery

    2011-11-01

    The year 2010 marked the 25th anniversary of the Center for Army Lessons Learned (CALL) as well as the Army Medical Department (AMEDD) Center and School's Lessons Learned Division. In the aftermath of Operation Urgent Fury in 1983, the Army recognized the need to create an organization whose sole purpose was to collect, review, and analyze lessons learned and created the CALL in 1985 at Fort Leavenworth, Kansas. The AMEDD followed suit and established the Medical Information System/AMEDD Lessons Learned office under the Directorate of Evaluation and Standardization to research and compile lessons learned as the AMEDD's point of contact for the CALL program. Over these past 25 years the AMEDD Center and School Lessons Learned program evolved and underwent organizational realignments, but the overall mission continues to promote changes either directly or indirectly in the AMEDD's Doctrine, Organizations, Training, Leader Development, Materiel, Personnel and Facilities domains and capabilities to provide combat health service support on the battlefield. PMID:22165647

  12. Proceedings of the 25th intersociety energy conversion engineering conference

    SciTech Connect

    Nelson, P.A.; Schertz, W.W.; Till, R.H.

    1990-01-01

    This book contains the proceedings of the 25th Intersociety Energy Conversion Engineering Conference. Volume 5 is organized under the following headings: Photovoltaics I, Photovoltaics II, Geothermal power, Thermochemical conversion of biomass, Energy from waste and biomass, Solar thermal systems for environmental applications, Solar thermal low temperature systems and components, Solar thermal high temperature systems and components, Wind systems, Space power sterling technology Stirling cooler developments, Stirling solar terrestrial I, Stirling solar terrestrial II, Stirling engine generator sets, Stirling models and simulations, Stirling engine analysis, Stirling models and simulations, Stirling engine analysis, Stirling engine loss understanding, Novel engine concepts, Coal conversion and utilization, Power cycles, MHD water propulsion I, Underwater vehicle powerplants - performance, MHD underwater propulsion II, Nuclear power, Update of advanced nuclear power reactor concepts.

  13. AFTI/F-16 50th flight team photo

    NASA Technical Reports Server (NTRS)

    1983-01-01

    An early (1983) photograph of the AFTI F-16 team, commemorating the aircraft's 50th flight. It shows the initial configuration and paint finish of the AFTI F-16, as well as the forward mounted canards and the spin chute. During the 1980s and 1990s, NASA and the U.S. Air Force participated in a joint program to integrate and demonstrate new avionics technologies to improve close air support capabilities in next-generation aircraft. The testbed aircraft, seen here in flight over the desert at NASA's Dryden Flight Research Center, Edwards, California, was called the Advanced Fighter Technology Integration (AFTI) F-16. The tests demonstrated technologies to improve navigation and the pilot's ability to find and destroy enemy ground targets day or night, including adverse weather. The aircraft--an F-16A Fighting Falcon (Serial #75-0750)--underwent numerous modifications. A relatively low-cost testbed, it evaluated the feasability of advanced, intergrated-sensor, avionics, and flight control technologies. During the first phase of the AFTI/F-16 program, which began in 1983, the aircraft demonstrated voice-actuated commands, helmet-mounted sights, flat turns, and selective fuselage pointing using forward-mounted canards and a triplex digital flight control computer system. The second phase of research, which began in the summer of 1991, demonstrated advanced technologies and capabilities to find and destroy ground targets day or night, and in adverse weather while using maneuverability and speed at low altitude. This phase was known as the close air support and battlefield air interdiction (CAS/BAI) phase. Finally, the aircraft was used to assess the Automatic Ground Collision Avoidance System (Auto - GCAS), a joint project with the Swedish Government. For these tests, the pilot flew the aircraft directly toward the ground, simulating a total loss of control. The GCAS was designed to take command in such emergencies and bring the aircraft back to level flight. The AFTI F

  14. 75 FR 33995 - Safety Zone; Michigan Orthopaedic Society 50th Anniversary Fireworks, Lake Huron, Mackinac Island...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Michigan Orthopaedic Society 50th... Society 50th Anniversary Fireworks display, June 19, 2010. This temporary safety zone is necessary to... vessels during the setup and launching of fireworks in conjunction with the Michigan Orthopaedic...

  15. 50th Yearbook of the National Reading Conference (Scottsdale, Arizona, December 2000)

    ERIC Educational Resources Information Center

    Hoffman, James V., Ed.; Schallert, Diane L., Ed.; Fairbanks, Colleen M., Ed.; Worthy, Jo, Ed.; Maloch, Beth, Ed.

    2001-01-01

    At the 2000 conference in Scottsdale, Arizona, the National Reading Conference celebrated its 50th anniversary, and with this issue, the editors offer to the readership the "50th Yearbook" of the conference. This Yearbook begins with a preface and presents profiles of two awardees, Lee Gunderson and Michael Pressley. Included in this Yearbook are…

  16. 3 CFR 8668 - Proclamation 8668 of May 3, 2011. 50th Anniversary of the Freedom Rides

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8668 of May 3, 2011. 50th Anniversary of the Freedom Rides 8668 Proclamation 8668 Presidential Documents Proclamations Proclamation 8668 of May 3, 2011 Proc. 8668 50th Anniversary of the Freedom RidesBy the President of the United States of America A Proclamation Fifty years ago,...

  17. 3 CFR 8631 - Proclamation 8631 of February 28, 2011. 50th Anniversary of the Peace Corps

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8631 of February 28, 2011. 50th Anniversary of the Peace Corps 8631 Proclamation 8631 Presidential Documents Proclamations Proclamation 8631 of February 28, 2011 Proc. 8631 50th Anniversary of the Peace CorpsBy the President of the United States of America A Proclamation In...

  18. 25th PolyMAC Conference, June 13-15, 1995

    SciTech Connect

    Smith, P.F.

    1995-06-01

    This document contains abstracts of reports presented at the 25th Annual Polymeric, Materials, Adhesives and Composites Symposium. Reports covered aging, testing and performance, and encapsulating materials.

  19. 76 FR 67799 - Pricing for the American Eagle 25th Anniversary Silver Coin Set

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY United States Mint Pricing for the American Eagle 25th Anniversary Silver Coin Set AGENCY: United States... price of the American Eagle 25th Anniversary Silver Coin Set. The coin set will be offered for sale at...

  20. Proceedings of the 25th Himalaya-Karakoram-Tibet Workshop

    USGS Publications Warehouse

    Leech, Mary L.; Klemperer, Simon L.; Mooney, Walter D.

    2010-01-01

    For a quarter of a century the Himalayan-Karakoram-Tibet (HKT) Workshop has provided scientists studying the India-Asia collision system a wonderful opportunity for workshop-style discussion with colleagues working in this region. In 2010, HKT returns to North America for the first time since 1996. The 25th international workshop is held from June 7 to10 at San Francisco State University, California. The international community was invited to contribute scientific papers to the workshop, on all aspects of geoscience research in the geographic area of the Tibetan Plateau and its bounding ranges and basins, from basic mapping to geochemical and isotopic analyses to large-scale geophysical imaging experiments. In recognition of the involvement of U.S. Geological Survey (USGS) scientists in a wide range of these activities, the USGS agreed to publish the extended abstracts of the numerous components of HKT-25 as an online Open-File Report, thereby ensuring the wide availability and distribution of these abstracts, particularly in the HKT countries from which many active workers are precluded by cost from attending international meetings. In addition to the workshop characterized by contributed presentations, participants were invited to attend a pre-meeting field trip from the Coast Ranges to the Sierra Nevada, to allow the international group to consider how the tectonic elements of the Pacific margin compare to those of the Himalayan belt. Following the workshop, the National Science Foundation (NSF) sponsored a workshop on the 'Future directions for NSF-sponsored geoscience research in the Himalaya/Tibet' intended to provide NSF Program Directors with a clear statement and vision of community goals for the future, including the scientific progress we can expect if NSF continues its support of projects in this geographic region, and to identify which key geoscience problems and processes are best addressed in the Himalaya and Tibet, what key datasets are needed, and

  1. Proceedings of the 25th Annual Stirling Physics Meeting 1999

    NASA Astrophysics Data System (ADS)

    McVey, Michael

    1999-09-01

    The 25th Annual Stirling Physics meeting took place on Thursday 20 May on a warm sunny day when the country setting of Stirling Campus could be seen at its best. A total of 225 participants from all sectors of physics education attended. There was an opportunity to view and discuss with exhibitors a wide range of state-of-the-art equipment and teaching materials both before and after the meeting. The theme of the meeting was `Maintaining Standards'. Gemmel Millar, Scottish Branch Secretary acting as Chairperson for the morning session and in anticipation of the first speaker, wondered if a new unit qualification, the `Planck' might be introduced. Half units would then be `Short Plancks' and how many Short Plancks must there be in a unit? Great stuff. Scottish Qualifications Authority Hugh McGill began with a brief history and description of the Scottish Qualifications Authority. Born on 1 April 1997 (a light frisson of amusement swept through the audience) it was a unification between SEB and SCOTVEC and has a range of responsibilities covering schools, further and higher education. It oversees Standard and Higher grades, HNC and HND and SVQs, and it has 500 full-time employees as well as some 13500 appointees who act as examiners, assessors and verifiers etc, without whom its remit could not be carried out. The committee structure of the Board was outlined, one each for national and higher national qualifications and a third for Scottish vocational qualifications. These will be served by a proposed 19 Advisory Groups. The Science Advisory Group will be the key body for advising SQA on strategic developments to ensure that qualifications meet the needs of both client groups and end users. A consultation paper `Added Value To Learning' was referred to, in which all qualifications available in Scotland are given parity of esteem on a rising 11-point scale. Mr McGill stated that standards would be best maintained by ensuring continuity in procedures developed over

  2. 75 FR 29658 - Safety Zone; America's Discount Tire 50th Anniversary, Fireworks Display, South Lake Tahoe, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; America's Discount Tire 50th Anniversary... support of America's Discount Tire 50th Anniversary Fireworks Display. This safety zone is established to... Discount Tire will sponsor their 50th Anniversary Celebration Fireworks Display on July 11 and 13, 2010,...

  3. 3 CFR 8829 - Proclamation 8829 of May 25, 2012. Commemoration of the 50th Anniversary of the Vietnam War

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the 50th Anniversary of the Vietnam War 8829 Proclamation 8829 Presidential Documents Proclamations Proclamation 8829 of May 25, 2012 Proc. 8829 Commemoration of the 50th Anniversary of the Vietnam WarBy the President of the United States of America A Proclamation As we observe the 50th anniversary of the...

  4. Proceedings of the 25th Annual Stirling Physics Meeting 1999

    NASA Astrophysics Data System (ADS)

    McVey, Michael

    1999-09-01

    The 25th Annual Stirling Physics meeting took place on Thursday 20 May on a warm sunny day when the country setting of Stirling Campus could be seen at its best. A total of 225 participants from all sectors of physics education attended. There was an opportunity to view and discuss with exhibitors a wide range of state-of-the-art equipment and teaching materials both before and after the meeting. The theme of the meeting was `Maintaining Standards'. Gemmel Millar, Scottish Branch Secretary acting as Chairperson for the morning session and in anticipation of the first speaker, wondered if a new unit qualification, the `Planck' might be introduced. Half units would then be `Short Plancks' and how many Short Plancks must there be in a unit? Great stuff. Scottish Qualifications Authority Hugh McGill began with a brief history and description of the Scottish Qualifications Authority. Born on 1 April 1997 (a light frisson of amusement swept through the audience) it was a unification between SEB and SCOTVEC and has a range of responsibilities covering schools, further and higher education. It oversees Standard and Higher grades, HNC and HND and SVQs, and it has 500 full-time employees as well as some 13500 appointees who act as examiners, assessors and verifiers etc, without whom its remit could not be carried out. The committee structure of the Board was outlined, one each for national and higher national qualifications and a third for Scottish vocational qualifications. These will be served by a proposed 19 Advisory Groups. The Science Advisory Group will be the key body for advising SQA on strategic developments to ensure that qualifications meet the needs of both client groups and end users. A consultation paper `Added Value To Learning' was referred to, in which all qualifications available in Scotland are given parity of esteem on a rising 11-point scale. Mr McGill stated that standards would be best maintained by ensuring continuity in procedures developed over

  5. National Center for Biotechnology Information Celebrates 25th Anniversary | NIH MedlinePlus the Magazine

    MedlinePlus

    ... page please turn JavaScript on. National Center for Biotechnology Information Celebrates 25th Anniversary Past Issues / Winter 2014 ... Photo courtesy of NLM The National Center for Biotechnology Information (NCBI), a component of NLM, celebrated its ...

  6. 78 FR 53235 - 50th Anniversary of the March on Washington for Jobs and Freedom

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    .... (Presidential Sig.) [FR Doc. 2013-21189 Filed 8-27-13; 11:15 am] Billing code 3295-F3 ... Documents#0;#0; ] Proclamation 9004 of August 23, 2013 50th Anniversary of the March on Washington for Jobs... remember that the March on Washington was a demonstration for jobs as well as freedom. The coalition...

  7. 77 FR 51473 - Safety Zone; Bostock 50th Anniversary Fireworks, Long Island Sound; Manursing Island, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Bostock 50th Anniversary Fireworks, Long... is establishing a temporary safety zone on the navigable waters of Long Island Sound in the vicinity... all vessels from a portion of Long Island Sound before, during, and immediately after the...

  8. 77 FR 34894 - Safety Zone; Bostock 50th Anniversary Fireworks, Long Island Sound; Manursing Island, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Bostock 50th Anniversary Fireworks, Long.... SUMMARY: The Coast Guard proposes to establish a temporary safety zone on the navigable waters of Long.... This rule is intended to restrict all vessels from a portion of Long Island Sound before, during,...

  9. Frontiers: Research Highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    DOE R&D Accomplishments Database

    1996-01-01

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  10. Frontiers: Research highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    SciTech Connect

    1996-12-31

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  11. Celebrating the 50th Anniversary of the "Merrill-Palmer Quarterly"

    ERIC Educational Resources Information Center

    Ladd, Gary W.

    2004-01-01

    The academic year 2004-2005 marks the 50th anniversary of the "Merrill-Palmer Quarterly: A Journal of Developmental Psychology." This occasion provides an opportunity to celebrate the journal's heritage, its long history of scholarly contributions to the human developmental sciences, and its current and future mission as a purveyor of scientific…

  12. The State of the World's Children, 1996 (50th Anniversary Issue).

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This special issue of "The State of the World's Children" marks the 50th anniversary year of UNICEF and its work on behalf of children. Chapter 1 examines how wars and civil conflicts are taking an enormous toll on children. The chapter outlines a proposed anti-war agenda as a vital step to prevent and alleviate the suffering of children in armed…

  13. Digest of Education Statistics 2014, 50th Edition. NCES 2016-006

    ERIC Educational Resources Information Center

    Snyder, Thomas D.; de Brey, Cristobal; Dillow, Sally A.

    2016-01-01

    The 2014 edition of the "Digest of Education Statistics" is the 50th in a series of publications initiated in 1962. The Digest has been issued annually except for combined editions for the years 1977-78, 1983-84, and 1985-86. Its primary purpose is to provide a compilation of statistical information covering the broad field of American…

  14. 75 FR 50843 - 75th Anniversary of the Social Security Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... From the Federal Register Online via the Government Publishing Office #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 75, No. 159 / Wednesday, August 18, 2010 / Presidential Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8546 of August 13, 2010 75th Anniversary of the Social Security Act By the President of the United States...

  15. 3 CFR 8613 - Proclamation 8613 of December 6, 2010. 50th Anniversary of the Arctic National Wildlife Refuge

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8613 of December 6, 2010. 50th Anniversary of the Arctic National Wildlife Refuge 8613 Proclamation 8613 Presidential Documents Proclamations Proclamation 8613 of December 6, 2010 Proc. 8613 50th Anniversary of the Arctic National Wildlife RefugeBy the President of the United States...

  16. 77 FR 21893 - Safety Zone; International Bridge 50th Anniversary Celebration Fireworks, St Mary's River, U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; International Bridge 50th Anniversary... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting, but you may.... 165.T09-0200 to read as follows: Sec. 165.T09-0200 Safety Zone International Bridge 50th...

  17. Mosquito vector biology and control in Latin America - A 25th Symposium

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 25th Annual Latin American Symposium presented by the American Mosquito Control Association (AMCA) was held as part of the 81st Annual Meeting in New Orleans, LA, in March 2015. The principal objective, for the previous 24 symposia, was to promote participation in the AMCA by vector control spec...

  18. Apollo-11 25th Arniversary celebration: Space Shuttle Main Engine - Technology Test Bed (SSME-TTB)

    NASA Technical Reports Server (NTRS)

    1994-01-01

    On the 25th Anniversary of the Apollo-11 space launch, Marshall celebrated with a test firing of the Space Shuttle Main Engine at the Technology Test Bed (SSME-TTB). This drew a large crowd who stood in the fields around the test site and watched as plumes of white smoke verified ignition.

  19. Editorial: Special issue highlighting research presented at the 25th IWGO Conference, Chicago 2014

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A joint international conference was held among corn insect entomologists from 15 countries at the Allerton Hotel, Chicago, Illinois on April 13-17, 2014. It combined the 25th IWGO (International Working Group on Ostrinia and other maize pests) Conference with the 4th Diabrotica Genetics Conference,...

  20. Symposium commemorating the 25th anniversary of the discovery of mendelevium

    SciTech Connect

    Seaborg, G.T.

    1980-01-01

    The Symposium honoring the 25th Anniversary of the discovery of mendelevium was held at the Lawrence Berkeley Laboratory on March 28, 1980. The following three papers were presented: Chemical Properties of Mendelevium; Nuclear Properties of Mendelevium; and Radioactive Decay of Md Isotopes. Besides these papers there were introductory remarks, reminiscences, and concluding remarks.

  1. Highlights from the 50th Seminar of the Korean Society of Gastrointestinal Endoscopy

    PubMed Central

    Kim, Eun Young; Choi, Il Ju; Kwon, Kwang An; Ryu, Ji Kon; Dong, Seok Ho

    2014-01-01

    The July issue of Clinical Endoscopy deals with selected articles covering the state-of-the-art lectures delivered during the 50th seminar of the Korean Society of Gastrointestinal Endoscopy (KSGE) on March 30, 2014, highlighting educational contents pertaining to either diagnostic or therapeutic gastrointestinal (GI) endoscopy, which contain fundamental and essential points in GI endoscopy. KSGE is very proud of its seminar, which has been presented twice a year for the last 25 years, and hosted more than 3,500 participants at the current meeting. KSGE seminar is positioned as one of premier state-of-the-art seminars for endoscopy, covering topics for novice endoscopists and advanced experts, as well as diagnostic and therapeutic endoscopy. The 50th KSGE seminar consists of more than 20 sessions, including a single special lecture, concurrent sessions for GI endoscopy nurses, and sessions exploring new technologies. Nine articles were selected from these prestigious lectures, and invited for publication in this special issue. This introductory review, prepared by the editors of Clinical Endoscopy, highlights core contents divided into four sessions: upper GI tract, lower GI tract, pancreatobiliary system, and other specialized topic sessions, including live demonstrations and hands-on courses. PMID:25133113

  2. Research activities on Antarctic middle atmosphere by JARE 25th team

    NASA Technical Reports Server (NTRS)

    Hirasawa, T.; Eiwasaka, Y. AFTANAKA, M. agfujii, r.0 typ; Eiwasaka, Y. AFTANAKA, M. agfujii, r.0 typ

    1985-01-01

    The Antarctic Middle Atmosphere (AMA)-Japan research project was set about by the JARE (Japan Antarctic Research Expedition) 23rd team in 1982, and since then the JARE-24th and JARE-25th teams have been continuing reseach on the Antarctic Middle Atmosphere. Results gained by JARE-25th team members who are now working at Syowa Station (69.99 deg S, 39.35 deg E), Antarctica are presented. In their activities satellite measurements (Exos-C) and rocket soundings are used. Three rockets of the S310 type were launched at Syowa Station (Geomagnetic Latitude = 69.9 deg S) for the purpose of directly observing the electron density, ionospheric temperature, auroral patterns and luminosity in situ. Vertical profiles of electron density and auroral emission 4278A measured by three rockets are compared.

  3. Alumni of High School Internship Program Return for 25th Anniversary to Inspire Current Students | Poster

    Cancer.gov

    The Building 549 auditorium is often packed with high school interns eager to hear a scientific lecture. On April 22, however, the room swelled with interns spanning a wider age range. At the 25th Werner H. Kirsten Student Intern Program (WHK SIP) Anniversary Symposium, incoming, current, and former interns gathered to celebrate the program, which has provided biomedical research experience for local high school seniors.

  4. Hubble’s 25th Anniversary: A Quarter-Century of Discovery and Inspiration

    NASA Astrophysics Data System (ADS)

    Straughn, Amber; Jirdeh, Hussein

    2015-01-01

    April 24, 2015 marks the 25th anniversary of the launch of the Hubble Space Telescope. In its quarter-century in orbit, the Hubble Space Telescope has transformed the way we understand the Universe, helped us find our place among the stars, and paved the way to incredible advancements in science and technology. NASA and ESA, including STScI and partners, will use the 25th anniversary of Hubble's launch as a unique opportunity to communicate to the widest possible audience the significance of the past quarter-century of discovery with the Hubble Space Telescope and to highlight that Hubble will continue to produce groundbreaking science results. We will enhance public understanding of Hubble's many contributions to the scientific world, and will capitalize on Hubble's cultural popularity by emphasizing its' successor, the James Webb Space Telescope. This poster highlights many of the upcoming opportunities to join in the anniversary activities, both in-person and online. Find out more at hubble25th.org and follow #Hubble25 on social media.

  5. Predictions of the onset of mini ice age in the 25th solar cycle

    NASA Astrophysics Data System (ADS)

    Kumar, Rajiv

    2016-07-01

    Predictions of the ir-regularty in the 11 year heartbeat of the sun due to asyncronous of the two layered dynamo effect would result in mini ice age as in the Maunder minimum.The onset of this event is expected in the begining of 25th solar cycle and would go to its maximum in the 26th solar cycle.The minimum temperature is expected in 2028 due to the fall of solar activity by 60 % termed as solar hibernation.The predictions are based on the observations obtained by the Royal Greenwich observatory since 1874. Keywords: Dynamo effect,munder minimum,Solar hybernation

  6. Injury risk curves for the WorldSID 50th male dummy.

    PubMed

    Petitjean, Audrey; Trosseille, Xavier; Petit, Philippe; Irwin, Annette; Hassan, Joe; Praxl, Norbert

    2009-11-01

    The development of the WorldSID 50th percentile male dummy was initiated in 1997 by the International Organisation for Standardisation (ISO/SC12/TC22/WG5) with the objective of developing a more biofidelic side impact dummy and supporting the adoption of a harmonised dummy into regulations. More than 45 organizations from all around the world have contributed to this effort including governmental agencies, research institutes, car manufacturers and dummy manufacturers. The first production version of the WorldSID 50th male dummy was released in March 2004 and demonstrated an improved biofidelity over existing side impact dummies. Full scale vehicle tests covering a wide range of side impact test procedures were performed worldwide with the WorldSID dummy. However, the vehicle safety performance could not be assessed due to lack of injury risk curves for this dummy. The development of these curves was initiated in 2004 within the framework of ISO/SC12/TC22/WG6 (Injury criteria). In 2008, the ACEA- Dummy Task Force (TFD) decided to contribute to this work and offered resources for a project manager to coordinate of the effort of a group of volunteer biomechanical experts from international institutions (ISO, EEVC, VRTC/NHTSA, JARI, Transport Canada), car manufacturers (ACEA, Ford, General Motors, Honda, Toyota, Chrysler) and universities (Wayne State University, Ohio State University, John Hopkins University, Medical College of Wisconsin) to develop harmonized injury risk curves. An in-depth literature review was conducted. All the available PMHS datasets were identified, the test configurations and the quality of the results were checked. Criteria were developed for inclusion or exclusion of PMHS tests in the development of the injury risk curves. Data were processed to account for differences in mass and age of the subjects. Finally, injury risk curves were developed using the following statistical techniques, the certainty method, the Mertz/Weber method, the

  7. 50th Year Anniversary of Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University.

    PubMed

    Lertakyamanee, Jariya

    2016-05-01

    Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, has started to be a formal anesthesia division, divided from division of Surgery in 1965; hence our 50th year anniversary in 2015. Research is now a priority and mandatory mission, according to the vision of Mahidol University. Second mission is to teach and train, and we produce the highest number of states-of-the-art anesthesiologists and anesthetic nurses each year Curriculum and training are being continuously improved. From a small unit, now it is one of the largest departments and extends the service, our third mission, to more than only in the operating theaters. We look after pre-anesthesia assessment, inside and outside operating room anesthesia, post-operative pain relief Intensive Care Unit, and chronic pain management. The number of patients and their diseases increase; so do the complexities of surgeries. There are tremendous changes in drugs and equipment. There is the fourth mission on administration, IT and resource management. And the fifth mission which is corporate social responsibility. However, we still believe that compassion, responsibility and integrity are most important. We have taught and tried to live by the teaching of HRH the King's Father. And these will contribute to our progress and shine in the next 50 years. PMID:27501620

  8. Mosquito Vector Biology and Control in Latin America-A 25TH Symposium.

    PubMed

    2015-09-01

    The 25th Annual Latin American Symposium presented by the American Mosquito Control Association (AMCA) was held as part of the 81st Annual Meeting in New Orleans, LA, in March 2015. The principal objective, as for the previous 24 symposia, was to promote participation in the AMCA by vector control specialists, public health workers, and academicians from Latin America. This publication includes summaries of 24 presentations that were given orally in Spanish by participants from Colombia, Mexico, and the USA. Topics addressed in the symposium included: surveillance, operations, ecology, chemical control, studies of dengue viruses, and insecticide resistance. Insect vectors included Aedes, Culex, and Anopheles mosquitoes in addition to phlebotomine sand flies and triatomine bugs. PMID:26375913

  9. [The Citizen Constitution and the 25th anniversary of the Brazilian Unified National Health System (SUS)].

    PubMed

    Paim, Jairnilson Silva

    2013-10-01

    This article, celebrating the 25th anniversary of Brazil's 1988 Constitution, aims to review the country's social policy development, discuss political projects, and analyze challenges for the sustainability of the Unified National Health System (SUS). Based on public policymaking studies, the article revisits the origins of liberal social policy, focused on social assistance, and analyzes the hegemony of U.S. policies targeting poverty and their repercussions for universal policies. After identifying the formulation of political projects in Brazil's democratic transition, it discusses their implications during the various Administrations since 1988, along with the difficulties faced by the National Health System. The article concludes that the political forces occupying government in the last two decades have failed to present a project for the country on the same level as those who drafted the Citizen Constitution. PMID:24127081

  10. The Daylight Bolide of 1996 April 25th , over Mt. Bruce, New Zealand

    NASA Astrophysics Data System (ADS)

    Wolf, G.; McBeath, A.

    On Thursday, 1996 April 25th (ANZAC Day in New Zealand) a bright daylight bolide with possible -22m end point, was seen from Newtown, Wellington, New Zealand at 02h20m12s. Its end-point altitude was calculated to be app. 15-20km over Mt. Bruce, some 80km NE of Wellington. A smoky train, initially 42deg long, was visible to the naked eye for 28 minutes afterwards. Sonics were heard by the New Zealand author, around 265s after the end point, suggesting a direct-line distance of 88km from the author's location. The impact point was probably several kilometers off Foxton Beach in the Tasman Sea. The bolide passed about 5deg above the first quarter Moon, and two photographs were secured, showing how the train began to drift, ultimately app. 17deg, to the south, before dissipating.

  11. Marshall Space Flight Center 1960-1985: 25th anniversary report

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The Marshall Space FLight Center marks its 25th aniversary with a record of notable achievements. These accomplishments are the essence of the Marshall Center's history. Behind the scenes of the space launches and missions, however, lies the story of challenges faced and problems solved. The highlights of that story are presented. The story is organized not as a straight chronology but as three parallel reviews of the major assignments: propulsion systems and launch vehicles, space science research and technology, and manned space systems. The general goals were to reach space, to know and understand the space environment, and to inhabit and utilize space for the benefit of mankind. Also included is a chronology of major events, presented as a fold-out chart for ready reference.

  12. 77 FR 33094 - Safety Zone; International Bridge 50th Anniversary Celebration Fireworks, St. Mary's River, U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; International Bridge 50th Anniversary..., Sault Sainte Marie, MI; in the Federal Register (77 FR 21893). We received 1 public submission... Locks, Sault Sainte Marie, MI; in the Federal Register (76 FR 22064). We received 1 public...

  13. Symposium--Perspectives on Motivation for Second Language Learning on the 50th Anniversary of Gardner & Lambert (1959)

    ERIC Educational Resources Information Center

    MacIntyre, Peter

    2010-01-01

    With the 50th anniversary of Robert C. Gardner and Wallace Lambert's seminal paper "Motivational variables in second language acquisition" (Gardner & Lambert 1959), we paused to reflect on the contributions the work has inspired and the state of the art in the study of motivation research.

  14. Proceedings of the 25th Seismic Research Review -- Nuclear Explosion Monitoring: Building the Knowledge Base

    SciTech Connect

    Chavez, Francesca C.; Mendius, E. Louise

    2003-09-23

    These proceedings contain papers prepared for the 25th Seismic Research Review -- Nuclear Explosion Monitoring: Building the Knowledge Base, held 23-25 September, 2003 in Tucson, Arizona. These papers represent the combined research related to ground-based nuclear explosion monitoring funded by the National Nuclear Security Administration (NNSA), Defense Threat Reduction Agency (DTRA), Air Force Research Laboratory (AFRL), US Army Space and Missile Defense Command, and other invited sponsors. The scientific objectives of the research are to improve the United States capability to detect, locate, and identify nuclear explosions. The purpose of the meeting is to provide the sponsoring agencies, as well as potential users, an opportunity to review research accomplished during the preceding year and to discuss areas of investigation for the coming year. For the researchers, it provides a forum for the exchange of scientific information toward achieving program goals, and an opportunity to discuss results and future plans. Paper topics include: seismic regionalization and calibration; detection and location of sources; wave propagation from source to receiver; the nature of seismic sources, including mining practices; hydroacoustic, infrasound, and radionuclide methods; on-site inspection; and data processing.

  15. NRAO Salutes Past, Looks to Future In 50th-Anniversary Science Meeting

    NASA Astrophysics Data System (ADS)

    2007-06-01

    Radio telescopes now in operation or under construction will be indispensible to scientists wrestling with the big, unanswered questions of 21st-Century astrophysics. That was the conclusion of a wide-ranging scientific meeting held in Charlottesville, Virginia, June 18-21, to mark the 50th anniversary of the National Radio Astronomy Observatory (NRAO). 1957 Dedication Dedication of NRAO, 17 October 1957. Left to right: R.M. Emberson, L.V. Berkner, G.A. Nay, J.W. Findlay (seated in front of 140ft telescope model), N.L. Ashton, D.S. Heeschen, H. Hockenberry. CREDIT: NRAO/AUI/NSF Click on Image for Larger File ALMA Artist's conception of completed ALMA. CREDIT: NRAO/AUI/ESO Click on Image for Larger File (2.4 MB) Nearly 200 scientists from around the world heard presentations about the frontiers of astrophysics and how the challenges at those frontiers will be met. In specialties as disparate as seeking the nature of the mysterious Dark Energy that is speeding the Universe's expansion to unraveling the details of how stars and planets are formed, more than 70 presenters looked toward future research breakthroughs. "NRAO's telescopes have made landmark contributions to the vast explosion of astronomical knowledge of the past half- century, and we look eagerly to making even more important contributions in the coming decades," said Fred K.Y. Lo, NRAO's director. Over the four days of the meeting, discussions ranged from recollections of radio astronomy's pioneering days of vacuum-tube equipment and paper chart recorders to the design of telescopes that will produce amounts of data that will strain today's computers. Presenters pointed out that, in the coming decades, radio telescope observations will advance not only astronomy but also fields of basic physics such as gravitational radiation, particle physics, and the fundamental physical constants. "This meeting provided a great overview of where astrophysics stands today and where the challenges and opportunities of

  16. The 50th Anniversary of the First International Conference on Permafrost

    NASA Astrophysics Data System (ADS)

    Brown, J.

    2013-12-01

    This year marks the 50th anniversary of the First International Conference on Permafrost (ICOP) that was held at Purdue University on 11-15 November 1963. The conference was a historic event in that it brought together for the first time the leading researchers and practitioners from North America and other countries that had diverse interests and activities in the study and applications of perennially frozen ground, cold regions engineering and related laboratory investigations. The 285 registered participants represented engineers, researchers, manufacturers and builders from the USA (231), Canada (42), the USSR (5), Sweden (3) and Argentina, Austria, Great Britain, Japan, Norway, Poland, Switzerland, and West Germany. The conference was organized by the Building Research Advisory Board of the U.S. National Academy of Sciences-National Research Council (NAS-NRC). The carefully edited volume, published in 1966 by the NAS, is considered to be the first multi-national, English-language collection of papers devoted entirely to permafrost topics. The 100 published papers followed closely the actual conference venue and panel discussions: soils and vegetation (9), massive ground ice (10), geomorphology (16), phase equilibrium and transition (8), thermal aspects (8), physico-mechanical properties (7), exploration and site selection (11), sanitary and hydraulic engineering (14), and earthwork and foundations (17). This 1963 Purdue conference essentially broke the 'ice' between East and West permafrost researchers and set the stage for the Second ICOP that was held in 1973 in Yakutsk, Siberia, and represented the first large international conference held in the restricted area of Siberia. All subsequent conferences maintained the interdisciplinary principles set forth at Purdue: two more in the United States (Fairbanks 1983, 2008), two in Canada (Edmonton 1978, Yellowknife 1998), and one in Trondheim, Norway (1988), Beijing, China (1993), and Zurich, Switzerland (2003

  17. The Prospects for Educational Planning. A Workshop Organised by IIEP on the Occasion of Its 25th Anniversary.

    ERIC Educational Resources Information Center

    Caillods, Francoise, Ed.

    In late 1988, on the occasion of its 25th anniversary celebration, the International Institute for Educational Planning organized an international workshop to review the major problems faced by education today and to consider the future of educational planning worldwide. The workshop brought together researchers, planners, and specialists from all…

  18. Echo-enabled harmonics up to the 75th order from precisely tailored electron beams

    NASA Astrophysics Data System (ADS)

    Hemsing, E.; Dunning, M.; Garcia, B.; Hast, C.; Raubenheimer, T.; Stupakov, G.; Xiang, D.

    2016-08-01

    The production of coherent radiation at ever shorter wavelengths has been a long-standing challenge since the invention of lasers and the subsequent demonstration of frequency doubling. Modern X-ray free-electron lasers (FELs) use relativistic electrons to produce intense X-ray pulses on few-femtosecond timescales. However, the shot noise that seeds the amplification produces pulses with a noisy spectrum and limited temporal coherence. To produce stable transform-limited pulses, a seeding scheme called echo-enabled harmonic generation (EEHG) has been proposed, which harnesses the highly nonlinear phase mixing of the celebrated echo phenomenon to generate coherent harmonic density modulations in the electron beam with conventional lasers. Here, we report on a demonstration of EEHG up to the 75th harmonic, where 32 nm light is produced from a 2,400 nm laser. We also demonstrate that individual harmonic amplitudes are controlled by simple adjustment of the phase mixing. Results show the potential of laser-based manipulations to achieve precise control over the coherent spectrum in future X-ray FELs for new science.

  19. PREFACE: 25th International Congress on Condition Monitoring and Diagnostic Engineering (COMADEM 2012)

    NASA Astrophysics Data System (ADS)

    Ball, Andrew; Mishra, Rakesh; Gu, Fengshou; Rao, Raj B. K. N.

    2012-05-01

    The proactive multidisciplinary conceptual philosophy of Condition Monitoring and Diagnostic Engineering Management (COMADEM) was conceived and has been nurtured, developed and sustained since 1988. Since then, it is gratifying to note that the condition monitoring, diagnostic and prognostic community worldwide (representing industrialists, academics, research and development organizations, professional/private establishments and many hardware/software vending organizations) has warmly welcomed and supported this venture. As is evidenced, many have reaped (and are reaping) the benefits of COMADEM interdiscipline through continuous knowledge discovery, generation and dissemination. We are now proud to celebrate the 25th Annual Event (Silver Jubilee) in Huddersfield, the most beautiful part of the United Kingdom. The theme of this Congress is 'Sustained Prosperity through Proactive Monitoring, Diagnosis, Prognosis and Management'. This proceedings is enriched by contributions from many keynote experts representing many industry and academic establishments worldwide. Authors from more than 30 different countries have pooled their rich multidisciplinary up-to-date knowledge, in order to share their invaluable experience with the COMADEM community. In this proceedings, the readers will find more than 120 refereed papers encompassing a number of topical areas of interest relating to the theme of the congress. The proceedings of COMADEM 2012 will appear in the Open Access Journal of Physics: Conference Series (JPCS), which is part of the IOP Conference Series. All papers published in the IOP Conference Series are fully citable and upon publication will be free to download. We would like to express our deep gratitude to all the keynote speakers, authors, referees, exhibitors, Technical Co-Sponsoring Organizations, Gold Sponsors, IOP Publishers, COMADEM 2012 organizing committee members, delegates and many others on whom the success of this prestigious event depends

  20. An Examination of Growth in Vocabulary and Phonological Awareness in Early Childhood: An Individual Growth Model Approach

    ERIC Educational Resources Information Center

    Cassano, Christina Marie

    2013-01-01

    The present study used individual growth modeling to examine the role of specific forms (i.e., receptive, expressive, and definitional vocabulary and grammatical skill) and levels of oral vocabulary skill (i.e., 25th, 50th, or 75th percentile) in phonological awareness growth during the preschool and kindergarten years. Sixty-one,…

  1. Earthquake Forecasts for Gorkha Immediately Following the 25th April, M=7.8 Mainshock

    NASA Astrophysics Data System (ADS)

    Segkou, M.; Parsons, T.

    2015-12-01

    The M-7.8 Gorkha (Nepal) earthquake on the 25th April, 2015 has shaken the central Himalayan front and immediately raised concerns for the severity of future triggered earthquakes. Here, we implement standard and innovative forecast models to predict the spatio-temporal distribution of triggered events. Key challenges addressed are: 1) the limited information on early aftershocks, 2) the low-productivity aftershock sequence in the near-source area, 3) the off-fault (>250 km) triggered events exemplified by the M=5.4 Xegar event, 3 hrs after the mainshock. We apply short-term empirical/statistical ETAS and physical forecast models, the latter based on the combination of rate/state friction law and Coulomb stresses. Within the physics-based model implementation we seek to evaluate the uncertainty related with the rupture style of triggered events by considering: 1) the geometry of active structures, 2) optimally oriented for failure faults and 3) all-potential faults described by the total stress field. The latter is represented by the full stress tensor before and after the mainshock and our analysis suggests that the preseismic stress magnitudes are still sufficient to cause earthquakes even after modification by the mainshock. The above remark reveals that there are no "stress shadows" affecting the spatial distribution of near-field aftershocks. It is also noted that the method allows for an a-priori determination of the rupture plan of the M=7.3 event, within the limit of uncertainty (20˚). The results show that: (1) ETAS models underestimate the number of observed events, since they heavily base their good performance in small magnitude earthquakes, not available in the first few weeks after the mainshock, (2) far field triggered events are captured only by physics-based forecasts, and (3) the total stress method improves the predictability of larger magnitude events. We conclude that frontier regions benefit from the implementation of physics-based models

  2. The 50th Anniversary of the International Indian Ocean Expedition: An Update on Current Planning Efforts and Progress

    NASA Astrophysics Data System (ADS)

    Hood, Raleigh; D'Adamo, Nick; Burkill, Peter; Urban, Ed; Bhikajee, Mitrasen

    2014-05-01

    The International Indian Ocean Expedition (IIOE) was one of the greatest international, interdisciplinary oceanographic research efforts of all time. Planning for the IIOE began in 1959 and the project officially continued through 1965, with forty-six research vessels participating under fourteen different flags. The IIOE motivated an unprecedented number of hydrographic surveys (and repeat surveys) over the course of the expedition covering the entire Indian Ocean basin. And it was an interdisciplinary endeavor that embraced physical oceanography, chemical oceanography, meteorology, marine biology, marine geology and geophysics. The end of 2015 will mark the 50th Anniversary of the completion of the IIOE. In the 50 years since the IIOE three fundamental changes have taken place in ocean science. The first is the deployment of a broad suite of oceanographic sensors on satellites that have dramatically improved the characterization of both physical and biological oceanographic variability. The second is the emergence of new components of the ocean observing system, most notably remote sensing and Argo floats. And the third is the development of ocean modeling in all its facets from short-term forecasting to seasonal prediction to climate projections. These advances have revolutionized our understanding of the global oceans, including the Indian Ocean. Compared to the IIOE era, we now have the capacity to provide a much more integrated picture of the Indian Ocean, especially if these new technologies can be combined with targeted and well-coordinated in situ measurements. In this presentation we report on current efforts to motivate an IIOE 50th Anniversary Celebration (IIOE-2). We envision this IIOE-2 as a 5-year expedition and effort beginning in 2015 and continuing through to 2020. An important objective of our planning efforts is assessing ongoing and planned research activities in the Indian Ocean in the 2015 to 2020 time frame, with the goal of embracing and

  3. REPORT FROM THE ORGANIZERS: The 25th International Conference on Low Temperature Physics

    NASA Astrophysics Data System (ADS)

    Kes, Peter

    2009-03-01

    The 25th International Conference on Low Temperature Physics (LT25) was hosted by the Kamerlingh Onnes Laboratorium of the Leiden Institute of Physics and held in the RAI Convention Center in Amsterdam, The Netherlands, 6-13 August 2008. It was the second time that the Kamerlingh Onnes Laboratory had the privilege of organizing an LT conference. In 1958, at LT6, 50 years of liquid helium temperatures were commemorated; in 2008 we celebrated the 100th anniversary of the remarkable achievements of Heike Kamerlingh Onnes and his collaborators in Leiden. In 1958 there were 323 participants and 145 papers appeared in the proceedings; in 2008 these numbers had increased to 1390 participants and 900 papers, of which eventually 849 were accepted. This large participation required adequate conference and housing facilities. These could not be found in Leiden, but were conveniently available in Amsterdam. The triennial International Low Temperature Conferences are organized under the auspices of the International Union of Pure and Applied Physics (IUPAP) through Commission C5 on Low Temperature Physics. It is the most important global meeting that brings together the international scientific community in the broad field of Low Temperature Physics. Because the meeting is held only every third year the 11 plenary and 22 half plenary talks (of 45 or 30 min.) generally provide an overview of important new discoveries over the last few years, whereas the 161 short oral presentations (20 min.) are mainly focused on very recent developments. Since the field is broad, embracing a large section of condensed matter physics, the program is divided into five parallel program lines: A. Quantum Gases, Fluids and Solids B. Superconductivity C. Quantum Phase Transitions and Magnetism D. Electronic Quantum Transport in Condensed Matter E. Cryogenic Techniques and Applications This distinction was used both to group the 1625 accepted abstracts, and the short-oral and poster presentations; the

  4. REPORT FROM THE ORGANIZERS: The 25th International Conference on Low Temperature Physics

    NASA Astrophysics Data System (ADS)

    Kes, Peter

    2009-03-01

    The 25th International Conference on Low Temperature Physics (LT25) was hosted by the Kamerlingh Onnes Laboratorium of the Leiden Institute of Physics and held in the RAI Convention Center in Amsterdam, The Netherlands, 6-13 August 2008. It was the second time that the Kamerlingh Onnes Laboratory had the privilege of organizing an LT conference. In 1958, at LT6, 50 years of liquid helium temperatures were commemorated; in 2008 we celebrated the 100th anniversary of the remarkable achievements of Heike Kamerlingh Onnes and his collaborators in Leiden. In 1958 there were 323 participants and 145 papers appeared in the proceedings; in 2008 these numbers had increased to 1390 participants and 900 papers, of which eventually 849 were accepted. This large participation required adequate conference and housing facilities. These could not be found in Leiden, but were conveniently available in Amsterdam. The triennial International Low Temperature Conferences are organized under the auspices of the International Union of Pure and Applied Physics (IUPAP) through Commission C5 on Low Temperature Physics. It is the most important global meeting that brings together the international scientific community in the broad field of Low Temperature Physics. Because the meeting is held only every third year the 11 plenary and 22 half plenary talks (of 45 or 30 min.) generally provide an overview of important new discoveries over the last few years, whereas the 161 short oral presentations (20 min.) are mainly focused on very recent developments. Since the field is broad, embracing a large section of condensed matter physics, the program is divided into five parallel program lines: A. Quantum Gases, Fluids and Solids B. Superconductivity C. Quantum Phase Transitions and Magnetism D. Electronic Quantum Transport in Condensed Matter E. Cryogenic Techniques and Applications This distinction was used both to group the 1625 accepted abstracts, and the short-oral and poster presentations; the

  5. 25th IAEA Fusion Energy Conference: summary of sessions EX/S, EX/W and ICC

    NASA Astrophysics Data System (ADS)

    Sen, A.

    2015-10-01

    This paper provides a summary overview, based on papers presented at the 25th IAEA Fusion Energy Conference (FEC), in the area of magnetic confinement experiments related to stability (EX/S), wave-plasma interactions, current drive, heating, energetic particles (EX/W) and innovative confinement concepts (ICCs). A selection of results that represent progress made since the last FEC in a few important thematic areas that are relevant for the successful and safe operation of future fusion devices like ITER, is highlighted.

  6. Newly diagnosed hyperthyroidism in the 25th gestational week of pregnancy presenting with systolic arterial hypertension only.

    PubMed

    Zaveljcina, Janez; Legan, Mateja; Gaberšček, Simona

    2016-05-01

    We present a case of a 30-year-old woman diagnosed with arterial hypertension in the 25th week of pregnancy. Our search for secondary causes of arterial hypertension revealed hyperthyroid Hashimoto's thyroiditis (HT), which was treated with propilthiouracil. Three weeks after delivery, she was normotensive without medication. In the next four months, she developed hypothyroidism and treatment with L-thyroxine was started. In conclusion, in the second half of pregnancy, a hyperthyroid HT can occur - in spite of the well-known amelioration of autoimmune thyroid disorders in that period, and can be the only cause of arterial hypertension. PMID:26979941

  7. Human Behavioral Pharmacology, Past, Present, and Future: Symposium Presented at the 50th Annual Meeting of the Behavioral Pharmacology Society

    PubMed Central

    Comer, Sandra D.; Bickel, Warren K.; Yi, Richard; de Wit, Harriet; Higgins, Stephen T.; Wenger, Galen R.; Johanson, Chris-Ellyn; Kreek, Mary Jeanne

    2010-01-01

    A symposium held at the 50th annual meeting of the Behavioral Pharmacology Society in May 2007 reviewed progress in the human behavioral pharmacology of drug abuse. Studies on drug self-administration in humans are reviewed that assessed reinforcing and subjective effects of drugs of abuse. The close parallels observed between studies in humans and laboratory animals using similar behavioral techniques have broadened our understanding of the complex nature of the pharmacological and behavioral factors controlling drug self-administration. The symposium also addressed the role that individual differences, such as gender, personality, and genotype play in determining the extent of self-administration of illicit drugs in human populations. Knowledge of how these factors influence human drug self-administration has helped validate similar differences observed in laboratory animals. In recognition that drug self-administration is but one of many choices available in the lives of humans, the symposium addressed the ways in which choice behavior can be studied in humans. These choice studies in human drug abusers have opened up new and exciting avenues of research in laboratory animals. Finally, the symposium reviewed behavioral pharmacology studies conducted in drug abuse treatment settings and the therapeutic benefits that have emerged from these studies. PMID:20664330

  8. Advanced optical correlation and digital methods for pattern matching—50th anniversary of Vander Lugt matched filter

    NASA Astrophysics Data System (ADS)

    Millán, María S.

    2012-10-01

    On the verge of the 50th anniversary of Vander Lugt’s formulation for pattern matching based on matched filtering and optical correlation, we acknowledge the very intense research activity developed in the field of correlation-based pattern recognition during this period of time. The paper reviews some domains that appeared as emerging fields in the last years of the 20th century and have been developed later on in the 21st century. Such is the case of three-dimensional (3D) object recognition, biometric pattern matching, optical security and hybrid optical-digital processors. 3D object recognition is a challenging case of multidimensional image recognition because of its implications in the recognition of real-world objects independent of their perspective. Biometric recognition is essentially pattern recognition for which the personal identification is based on the authentication of a specific physiological characteristic possessed by the subject (e.g. fingerprint, face, iris, retina, and multifactor combinations). Biometric recognition often appears combined with encryption-decryption processes to secure information. The optical implementations of correlation-based pattern recognition processes still rely on the 4f-correlator, the joint transform correlator, or some of their variants. But the many applications developed in the field have been pushing the systems for a continuous improvement of their architectures and algorithms, thus leading towards merged optical-digital solutions.

  9. Highlights of the 25th Anniversary EANM Congress Milan 2012: nuclear medicine and molecular imaging at its best.

    PubMed

    Langsteger, Werner; Beheshti, Mohsen

    2013-09-01

    The European Association of Nuclear Medicine (EANM) celebrated its 25th Anniversary Congress in Milan under the chairmanship of Professor Emilio Bombardieri and the auspices of the Italian Society of Nuclear Medicine. As always, the Congress was a great success: more than 5,530 participants from 88 countries came from Europe and beyond. In spite of limited budgets, industry again made an important contribution: New innovative equipment and tracers demonstrating the latest technology and innovations were presented by 122 companies. This review is a brief summary of the major scientific contributions made in the fields of oncology, multimodality imaging, cardiovascular science, neurology and psychiatry, technological innovation and novel tracers, and in other clinical sciences as well as in radionuclide therapy, which all show promising and great innovations. PMID:23917722

  10. 50th Anniversary of the first successful permanent pacemaker implantation in the United States: historical review and future directions.

    PubMed

    Beck, Hiroko; Boden, William E; Patibandla, Sushmitha; Kireyev, Dmitriy; Gutpa, Vipul; Campagna, Franklin; Cain, Michael E; Marine, Joseph E

    2010-09-15

    June 2010 marks the 50th anniversary of the first successful human cardiac pacemaker implantation in the United States. On June 6, 1960, in Buffalo, New York, Dr. William Chardack implanted a pacemaker, designed and built by Wilson Greatbatch, an electrical engineer and inventor, in a 77-year old man with complete atrioventricular block, extending the patient's life by 18 months. This landmark event ushered in a new era of implantable cardiac pacemakers with batteries and leads of high reliability and increasing durability. Over the past half century, the field of electrophysiology and implantable devices for the management of cardiac conduction disturbances has evolved dramatically. Today's pacemakers include increasingly complex features such as telemetry monitoring, auto programmability, and hemodynamic sensors. New-generation leads present a sophisticated design with improved geometry and steroid-eluting tips to reduce chronic inflammation, maintaining a low pacing threshold and high sensing capability. The lithium iodide battery remains the mainstay of implantable pacemaker systems, exhibiting a multiple-year lifespan, slow terminal decay, and a reduced size and cost of production. Although Greatbatch's first successful pacemaker implantation remains a seminal scientific contribution to modern cardiovascular disease management, emerging developments in this field may challenge its preeminence. Important challenges such as imaging compatibility, lead durability, and infection prevention are being addressed. Novel concepts such as leadless and biologic pacing are under active investigation. In conclusion, Greatbatch's historic achievement 50 years ago reminds us that technologic progress is timeless, as efforts to enhance clinical outcomes and the quality of life continue unimpeded into the 21st century. PMID:21391322

  11. Educating Black Librarians. Papers from the 50th Anniversary Celebration of the School of Library and Information Sciences, North Carolina Central University.

    ERIC Educational Resources Information Center

    Speller, Benjamin F., Jr., Ed.

    This document assembles 16 papers given at a 1989 symposium in honor of the 50th anniversary of the School of Library and Information Sciences at North Carolina Central University, Durham (NCCU). The papers examine the past, present, and future of the participation of African Americans in the field of library and information service. Titles…

  12. The Long Good-Bye: Why B. F. Skinner's "Verbal Behavior" Is Alive and Well on the 50th Anniversary of Its Publication

    ERIC Educational Resources Information Center

    Schlinger, Henry D.

    2008-01-01

    The year 2007 marked the 50th anniversary of the publication of B. F. Skinner's "Verbal Behavior", a book that by Skinner's own account was his most important. The received view, however, is that a devastating review by a young linguist not only rendered Skinner's interpretation of language moot but was also a major factor in ending the hegemony…

  13. Visual Literacy in the Digital Age: Selected Readings from the Annual Conference of the International Visual Literacy Association (25th, Rochester, New York, October 13-17, 1993).

    ERIC Educational Resources Information Center

    Beauchamp, Darrel G.; And Others

    This document contains selected papers from the 25th annual conference of the International Visual Literacy Association (IVLA). Topics addressed in the papers include the following: visual literacy; graphic information in research and education; evaluation criteria for instructional media; understanding symbols in business presentations;…

  14. Deeply Rooted, Branching Out, 1972-1997. Annual AEE International Conference Proceedings (25th, Asheville, North Carolina, November 23-26, 1997).

    ERIC Educational Resources Information Center

    Harwell, Rick, Ed.; Comstedt, Timothea, Ed.; Roberts, Nina, Ed.

    This proceedings contains 36 papers presented at the 25th Annual Conference of the Association for Experiential Education. Papers are: "The Woods and the Trees: Interpreting Experiential Education for Schools and a Greater Audience" (Joanna Allen, John Hutchinson); "Adventure Programming & Prevention of Adolescent Problem Behaviors: Applying…

  15. Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (25th, Utrecht, The Netherlands, July 12-17, 2001). Volumes 1-4.

    ERIC Educational Resources Information Center

    van den Heuvel-Panhuizen, Marja, Ed.

    This document contains the proceedings of the 25th annual Conference of the International Group for the Psychology of Mathematics Education (PME). It features plenary lectures, research forums, discussion groups, working sessions, short oral communications, and poster presentations. Papers in Volume 1 include: (1) "The P in PME: Progress and…

  16. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference (25th, Tarrytown, New York, March 25-26, 2011)

    ERIC Educational Resources Information Center

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2011-01-01

    Conference proceedings of the 25th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2011 was: The Future of the Undergraduate Psychology Major: New Directions in an Evolving Educational Climate. The Conference…

  17. Proceedings of the Anniversary Meeting (25th, Toronto, December 28-29, 1972). Industrial Relations Research Association Series. Index of IRRA Publications 1966-1972.

    ERIC Educational Resources Information Center

    Somers, Gerald G., Ed.

    Papers presented at the 25th meeting of the Industrial Relations Research Association (IRAA) covered issues that are central to industrial relations in North America. Papers and discussions dealt with these major issues: (1) Prices and Income Policy: Comparative Aspects, (2) Dispute Settlement in the Public Sector, (3) Manpower Policies in Canada…

  18. The MetLife Survey of the American Teacher: Past, Present and Future. A Survey of Teachers, Principals and Students. 25th Anniversary Edition

    ERIC Educational Resources Information Center

    MetLife, Inc., 2008

    2008-01-01

    This report is the twenty-fifth in a series of surveys sponsored annually by MetLife since 1984 as a public service. This 25th anniversary edition includes the views of teachers, principals and students and looks back to the earliest MetLife Surveys to examine how perspectives on teachers, teaching and public education have changed. It documents…

  19. Effect of Anatomical Modeling on Space Radiation Dose Estimates: A Comparison of Doses for NASA Phantoms and 5th, 50th, and 95th Percentile UF Hybrid Phantoms

    NASA Technical Reports Server (NTRS)

    Bahadori, A.; VanBaalen, M.; Shavers, M.; Semones, E.; Dodge, C.; Bolch, W.

    2010-01-01

    The estimate of absorbed dose to individual organs of a space crewmember is affected by the geometry of the anatomical model of the astronaut used in the radiation transport calculation. For astronaut dosimetry, NASA currently uses the computerized anatomical male (CAM) and computerized anatomical female (CAF) stylized phantoms to represent astronauts in its operational radiation dose analyses. These phantoms are available in one size and in two body positions. In contrast, the UF Hybrid Adult Male and Female (UFHADM and UFHADF) phantoms have organ shapes based on actual CT data. The surfaces of these phantoms are defined by non-uniform rational B-spline surfaces, and are thus flexible in terms of body morphometry and extremity positioning. In this study, UFHADM and UFHADF are scaled to dimensions corresponding to 5th, 50th, and 95th percentile (PCTL) male and female astronauts. A ray-tracing program is written in Visual Basic 2008, which is then used to create areal density maps for dose points corresponding to various organs within the phantoms. The areal density maps, along with appropriate space radiation spectra, are input into the NASA program couplet HZETRN/BRYNTRN, and organ doses are calculated. The areal density maps selected tissues and organs of the 5th, 50th, and 95th PCTL male and female phantoms are presented and compared. In addition, the organ doses for the 5th, 50th, and 95th PCTL male and female phantoms are presented and compared to organ doses for CAM and CAF.

  20. Case study: An isolated severe storm with giant hail hit Slovenian capital city Ljubljana on May 25th 2009

    NASA Astrophysics Data System (ADS)

    Korosec, M.

    2009-09-01

    Introduction A quite unusual weather pattern for month of May with first and early season heat wave of year 2009 resulted in several days of active severe storms across central Europe and Alpine region. Synoptic situation On May 25th 2009, an omega block pattern with strong upper-level subtropical ridge extending over Mediterranean and Balkan Peninsula brought stable and warm conditions into Southern Europe. Elsewhere, two large-scale troughs were located over Western and Eastern Europe with very unstable environment. On the nose of the Mediterranean ridge a jet streak with moderate shear was placed while over the Southern Alpine region only weak shear was placed over Slovenia. Rich boundary layer moisture and steep lapse rates within an elevated mixed layer favored extreme amounts of CAPE. After strong diurnal heating and surface wind convergence along the local topography a few convective cells were triggered in the mountainous terrain while deep moist convection over the rest of Slovenia was trapped by the strong capping inversion. In late afternoon several cells from the mountainous terrain interfered with each other and explosive convective cell was initiated along their outflow boundaries. Increasing near surface southeasterly wind flow supported enhanced low-level shear and storm relative helicity which caused this cell to very rapidly grown into an organized supercell storm on the flat terrain in northern Slovenia. This supercell then started racing southeastwards towards Ljubljana, a capital city of Slovenia. It caused extensive hail damage with very large to giant hailstones up to 7cm in diameter falling over parts of Ljubljana and areas north and southeast of the city. Presentation of research This case study will go through a research of this very damaging hailstorm, throughout a detailed analysis of the synoptic situation including analysis of satellite, radar and surface observations. At first, forecasting models did not suggest organized convection

  1. 38 CFR 12.13 - Posting of notice of the provisions of Pub. L. No. 734, 75th Congress (38 U.S.C. 16-16j).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Posting of notice of the provisions of Pub. L. No. 734, 75th Congress (38 U.S.C. 16-16j). 12.13 Section 12.13 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS DISPOSITION OF VETERAN'S PERSONAL FUNDS AND EFFECTS Disposition of Veteran's Personal...

  2. MABAHISS/John Murray 50th Anniversary: Marine Science of the North West Indian Ocean and Adjacent Waters. Report of a Symposium on the Occasion of the 50th Anniversary of the MABAHISS/John Murray Expedition (1933/34) (Alexandria, Egypt, September 3-7, 1983). Unesco Reports in Marine Science, No. 31.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Div. of Marine Sciences.

    An international symposium was convened to celebrate the 50th anniversary of the John Murray Expedition to the Indian Ocean on board the Egyptian research vessel Mabahiss (1933-1934). This report describes the symposium and provides abstracts and syntheses of the papers presented in the various marine scientific disciplines covering the areas of…

  3. Summary of the Workshop on Molten Salt Reactor Technologies Commemorating the 50th Anniversary of the Startup of the Molten Salt Reactor Experiment

    SciTech Connect

    Betzler, Benjamin R; Mays, Gary T

    2016-01-01

    A workshop on Molten Salt Reactor (MSR) technologies commemorating the 50th anniversary of the Molten Salt Reactor Experiment (MSRE) was held at Oak Ridge National Laboratory on October 15 16, 2015. The MSRE represented a pioneering experiment that demonstrated an advanced reactor technology: the molten salt eutectic-fueled reactor. A multinational group of more than 130 individuals representing a diverse set of stakeholders gathered to discuss the historical, current, and future technical challenges and paths to deployment of MSR technology. This paper provides a summary of the key messages from this workshop.

  4. The dawn of open heart surgery: an overview of the symposium that celebrated the 50th anniversary of controlled cross circulation.

    PubMed

    DeWall, Richard

    2005-01-01

    At the 50th Anniversary of Open Heart Surgery symposium sponsored by the Lillehei Heart Institute of the University of Minnesota in October 2004, the following pioneers in open heart surgery development presented papers of historical interest: Drs. Peter Agre, Robert W. Anderson, William Baumgartner, Alain Carpentier, Aldo Casteneda, Randolph Chitwood, Jr., Denton Cooley, Fred Crawford, Michael DeBakey, Richard DeWall, Vincent Gott, Claude Lenfant, Floyd Loop, James Holler, Glen Nelson, Norman Shumway, Manny Villafana, Richard Weisel, and Sir Magdi Yacoub. PMID:16106145

  5. A report from the European Association for the Study of the Liver's 50th International Liver Congress (April 22-26 - Vienna, Austria).

    PubMed

    Rabasseda, X

    2015-04-01

    While Vienna's Prater park offers a varied selection of options, from theme parks to lush gardens and prairies to enjoy the sun, the nearby Messe Wien convention center was the focus of attention in April 2015 for all the scientists, researchers and clinicians interested in viral hepatitis, nonalcoholic steatohepatitis, hepatocellular carcinoma and a variety of other liver diseases. Treatments and potential new therapeutic strategies for these hepatopathies were discussed during the 50th International Liver Congress organized by the European Association for the Study of the Liver. Echoing epidemiological facts and a high social interest for hepatitis C virus infection, new findings with investigational and potential new therapies for the disease centered much of the attention at the conference. Nevertheless, new research was also reported related to potential improvements in how other liver diseases, particularly hepatitis B virus infection, hepatocellular carcinoma and a range of inflammatory and immune-mediated liver diseases, including rare hereditary diseases that should never be forgotten. PMID:26020068

  6. Thoracic response targets for a computational model: a hierarchical approach to assess the biofidelity of a 50th-percentile occupant male finite element model.

    PubMed

    Poulard, David; Kent, Richard W; Kindig, Matthew; Li, Zuoping; Subit, Damien

    2015-05-01

    Current finite element human thoracic models are typically evaluated against a limited set of loading conditions; this is believed to limit their capability to predict accurate responses. In this study, a 50th-percentile male finite element model (GHBMC v4.1) was assessed under various loading environments (antero-posterior rib bending, point loading of the denuded ribcage, omnidirectional pendulum impact and table top) through a correlation metric tool (CORA) based on linearly independent signals. The load cases were simulated with the GHBMC model and response corridors were developed from published experimental data. The model was found to be in close agreement with the experimental data both qualitatively and quantitatively (CORA ratings above 0.75) and the response of the thorax was overall deemed biofidelic. This study also provides relevant corridors and an objective rating framework that can be used for future evaluation of thoracic models. PMID:25681717

  7. Introduction to the special issue: 50th anniversary of APA Division 28: The past, present, and future of psychopharmacology and substance abuse.

    PubMed

    Stoops, William W; Sigmon, Stacey C; Evans, Suzette M

    2016-08-01

    This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record PMID:27454671

  8. EDITORIAL: 50th anniversary issue

    NASA Astrophysics Data System (ADS)

    Beddoe, Alun H.

    2006-07-01

    In July 1956, 50 years ago, the first issue of Physics in Medicine and Biology (PMB) was published. It was subtitled The Journal of the Hospital Physicists' Association and published in association with the Philosophical Magazine by Taylor and Francis. Subscriptions were £1 per part or £3 10s for an annual subscription. The Editor, Professor J E Roberts, prefaced the first issue with a cautious editorial noting: The appearance of a new journal is usually greeted with mixed feelings by scientific workers, a common response being that there are far too many journals already. Justification for a new publication is only possible if there is a clearly defined gap in the publishing facilities available to workers in a particular scientific field.... Professor Roberts ended by seeking support from the scientific community for the new venture. He certainly got it! From a tentative few hundred pages in four issues a year for the first few years, the journal is now issued twice monthly with nearly 8000 pages expected in volume 51. In this anniversary issue we have invited some 28 senior authors to submit papers on a range of subjects spanning the discipline. We decided that to be an author one had to be old, but age was not to be the only criterion! Indeed readers will recognize all names as major contributors to both the development of medical physics and the success of PMB. Authors were not asked to write formal topical reviews of the state-of-the-art of the sub-disciplines which make up medical physics, but rather to present short historical reviews, didactic in style, perhaps highlighting the role of PMB in the development of their fields. Nevertheless, other than a page limit (which many subsequently ignored!) no formal format was imposed on authors, so what follows is a range of contributions from the almost conversational, personal statement to the more formal and familiar scientific paper. Whatever the writing style we are confident that readers will gain some appreciation of the development of our wide-ranging discipline over the last half century. Some readers may feel that one or two subjects have not been represented, and for that I can only apologise. We did ask for contributions to several other topics (for example radiation metrology and optical techniques) but inevitably there were authors who for various reasons were unable to meet the deadline. Inevitably we will also have missed contributions from excellent potential authors (who satisfied the age criterion!). As Guest Editor I must bear the responsibility for those omissions. While page limits do not permit me to discuss the contributions to this issue individually I would like to mention the first contribution by Dr J E (Bob) Burns. Dr Burns was on the Editorial Board in the early sixties working with the second Editor, Professor Sir Joseph Rotblat. Both in his article and in personal communications Dr Burns has emphasized the important role of Professor Rotblat in the early years. I did write to Professor Rotblat seeking a contribution from him but, sadly, received a reply saying that he was not well enough to contribute `at present'; he died a few weeks later at the age of 96 years (please refer to www.pugwash.org for tributes from Mikhail Gorbachev, Kofi Annan and many others). Dr Burns wrote a short note to me shortly after his death including the following comment which is reproduced below: Although many people have contributed to the success of PMB over the last 50 years it was Rotblat's restless energy, power of persuasion and already existing fame (he was well known both scientifically and to the public at the time) that enabled him to rescue the journal from an early death. After discussions with colleagues around the UK, including Dr Burns, and with the Editorial Board, we all felt that it would be highly appropriate to dedicate this anniversary issue to the memory of Professor Rotblat. Institute of Physics Publishing (IOP) took over the publishing of PMB in 1972, firstly on behalf of the Hospital Physicists' Association and then on behalf of the I

  9. 50th Anniversary: Freedom 7

    NASA Video Gallery

    On May 5, 1961, Alan Shepard was propelled into space aboard the Mercury capsule Freedom 7. His 15-minute suborbital flight was part of Project Mercury, the United States' first man-in-space progra...

  10. Increased Physical Activity and Fitness above the 50(th) Percentile Avoid the Threat of Older Adults Becoming Institutionalized: A Cross-sectional Pilot Study.

    PubMed

    Pereira, Catarina; Fernandes, Jorge; Raimundo, Armando; Biehl-Printes, Clarissa; Marmeleira, José; Tomas-Carus, Pablo

    2016-02-01

    The objective of this study was to analyze the impact of physical fitness and physical activity on the threat of older adults without cognitive impairment becoming institutionalized. This cross-sectional study involved 195 non-institutionalized (80.1 ± 4.4 years) and 186 institutionalized (83.8 ± 5.2years) participants. Cognitive impairment was assessed using Mini-Mental State Examination, measures of physical fitness were determined by the Senior Fitness Test, and physical activity was assessed using the International Physical Activity Questionnaire. Multivariate binary logistic analysis selected four main determinants of institutionalization in both genders: The likelihood of becoming institutionalized increased by +18.6% for each additional year of age, whereas it decreased by -24.8% by each fewer kg/m(2) in body mass index (BMI), by -0.9% for each additional meter performed in the aerobic endurance test, and by -2.0% for each additional 100 metabolic equivalent of task (MET)-min/week of physical activity expenditure (p < 0.05). Values ≤50(th) percentile (age ≥81 years, BMI ≥26.7 kg/m(2), aerobic endurance ≤367.6 meters, and physical activity ≤693 MET-min/week) were computed using receiver operating characteristics analysis as cutoffs discriminating institutionalized from non-institutionalized older adults. The performance of physical activity, allied to an improvement in physical fitness (mainly BMI and aerobic endurance), may avoid the threat of institutionalization of older adults without cognitive impairment only if they are above the 50(th) percentile. The following parameters are highly recommended: Expending ≥693 MET-min/week on physical activity, having a BMI ≤26.7 kg/m(2), and being able to walk ≥367.6 meters in the aerobic endurance test, especially above the age of 80 years. The discovery of this trigger justifies the development of physical activity programs targeting the pointed cutoffs in old and very old adults

  11. A portrait of the C4 photosynthetic family on the 50th anniversary of its discovery: species number, evolutionary lineages, and Hall of Fame.

    PubMed

    Sage, Rowan F

    2016-07-01

    Fifty years ago, the C4 photosynthetic pathway was first characterized. In the subsequent five decades, much has been learned about C4 plants, such that it is now possible to place nearly all C4 species into their respective evolutionary lineages. Sixty-one independent lineages of C4 photosynthesis are identified, with additional, ancillary C4 origins possible in 12 of these principal lineages. The lineages produced ~8100 C4 species (5044 grasses, 1322 sedges, and 1777 eudicots). Using midpoints of stem and crown node dates in their respective phylogenies, the oldest and most speciose C4 lineage is the grass lineage Chloridoideae, estimated to be near 30 million years old. Most C4 lineages are estimated to be younger than 15 million years. Older C4 lineages tend to be more speciose, while those younger than 7 million years have <43 species each. To further highlight C4 photosynthesis for a 50th anniversary snapshot, a Hall of Fame comprised of the 40 most significant C4 species is presented. Over the next 50 years, preservation of the Earth's C4 diversity is a concern, largely because of habitat loss due to elevated CO2 effects, invasive species, and expanded agricultural activities. Ironically, some members of the C4 Hall of Fame are leading threats to the natural C4 flora due to their association with human activities on landscapes where most C4 plants occur. PMID:27053721

  12. JANNAF 25th Airbreathing Propulsion Subcommittee, 37th Combustion Subcommittee and 1st Modeling and Simulation Subcommittee Joint Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Fry, Ronald S.; Becker, Dorothy L.

    2000-01-01

    Volume I, the first of three volumes, is a compilation of 24 unclassified/unlimited-distribution technical papers presented at the Joint Army-Navy-NASA-Air Force (JANNAF) 25th Airbreathing Propulsion Subcommittee, 37th Combustion Subcommittee and 1st Modeling and Simulation Subcommittee (MSS) meeting held jointly with the 19th Propulsion Systems Hazards Subcommittee. The meeting was held 13-17 November 2000 at the Naval Postgraduate School and Hyatt Regency Hotel, Monterey, California. Topics covered include: a Keynote Address on Future Combat Systems, a review of the new JANNAF Modeling and Simulation Subcommittee, and technical papers on Hyper-X propulsion development and verification; GTX airbreathing launch vehicles; Hypersonic technology development, including program overviews, fuels for advanced propulsion, ramjet and scramjet research, hypersonic test medium effects; and RBCC engine design and performance, and PDE and UCAV advanced and combined cycle engine technologies.

  13. Clinical Study of the Necessity of Replanning Before the 25th Fraction During the Course of Intensity-Modulated Radiotherapy for Patients With Nasopharyngeal Carcinoma

    SciTech Connect

    Wang Wei; Yang Haihua; Hu Wei; Shan Guoping; Ding Weijun; Yu Changhui; Wang Biyun; Wang Xufeng; Xu Qianyi

    2010-06-01

    Purpose: To quantify the target and normal structures on dose distributing variations during intensity-modulated radiotherapy (IMRT) and to assess the value of replanning for nasopharyngeal carcinoma (NPC) patients. Methods and Materials: Twenty-eight NPC patients treated with IMRT were recruited. The IMRT was delivered in 33 fractions, to 70 to 76Gy, to the gross tumor volume (GTV). Before the 25th fraction of IMRT, a new simulation computed tomography (CT) scan was acquired for all patients. According to the dose constraint criterion in the Radiation Therapy Oncology Group (RTOG) 0225 protocol, the replanning was generated on the new simulation CT. With the Quality Assessment Center of a CORVUS 6.3 treatment planning system, a phantom plan was generated for each patient by applying the beam configurations of the initial plan to the anatomy of the new simulation CT. The dose-volume histograms of the phantom plan were compared with the replanning. Results: The percentage of prescription dose delivered to the clinical target volume (CTV1) was significantly increased by 4.91% +- 10.89%, whereas the maximum dose to the spinal cord, mean dose to the left parotid, and V30 to the right parotid were significantly decreased by 5.00 +- 9.23Gy, 4.23 +- 10.03Gy, and 11.47% +- 18.89% respectively in the replanning, compared with the phantom plan (p < 0.05). Based on the dose constraint criterion in the RTOG0225 protocol, 50% of phantom plans (14/28) were out of limit for the dose to the normal critical structures, whereas no plan was out of limit in replanning (p < 0.001). Conclusion: Replanning for patients with NPC before the 25th fraction during IMRT helps to ensure adequate dose to the target volumes and safe doses to critical normal structures.

  14. Rural Sociology: The Wisconsin Contribution, Current Status and Future Directions. Proceedings of the 50th Anniversary Symposium of the Department of Rural Sociology, University of Wisconsin (Madison, Wisconsin, May 8-9, 1982).

    ERIC Educational Resources Information Center

    Wisconsin Univ., Madison. Coll. of Agricultural and Life Sciences.

    Papers presented at a symposium commemorating the 50th anniversary of the founding of the Department of Rural Sociology of the University of Wisconsin-Madison are collected in this volume. The first four papers--by Olaf Larson, Edward Moe, Daryl Hobbs, and Robert Gard--discuss the department's history, emphasizing the contributions of outstanding…

  15. Ceremony 25th birthday Cern

    SciTech Connect

    2006-05-08

    Célébration du 25ème anniversaire du Cern (jour par jour) avec discours de L.Van Hove et J.B.Adams, des interludes musicals offerts par Mme Mey et ses collègues (au debut 1.mouvement du quatuor avec piano no 3 de L.van Beethoven) Les directeurs généraux procéderont à la remise du souvenir aux membres de personnel ayant 25 années de service dans l'organisation. Un témoignage de reconnaissance est auss fait à l'interprète Mme Zwerner

  16. Ceremony 25th birthday Cern

    ScienceCinema

    None

    2011-04-25

    Célébration du 25ème anniversaire du Cern (jour par jour) avec discours de L.Van Hove et J.B.Adams, des interludes musicals offerts par Mme Mey et ses collègues (au debut 1.mouvement du quatuor avec piano no 3 de L.van Beethoven) Les directeurs généraux procéderont à la remise du souvenir aux membres de personnel ayant 25 années de service dans l'organisation. Un témoignage de reconnaissance est auss fait à l'interprète Mme Zwerner

  17. 25th Birthday Cern- Restaurant

    ScienceCinema

    None

    2011-04-25

    Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

  18. 25th Birthday Cern- Amphi

    ScienceCinema

    None

    2011-04-25

    Cérémonie du 25ème anniversaire du Cern avec 2 orateurs: le Prof.Weisskopf parle de la signification et le rôle du Cern et le Prof.Casimir(?) fait un exposé sur les rélations entre la science pure et la science appliquée et la "big science" (science légère)

  19. Standing adult human phantoms based on 10th, 50th and 90th mass and height percentiles of male and female Caucasian populations

    NASA Astrophysics Data System (ADS)

    Cassola, V. F.; Milian, F. M.; Kramer, R.; de Oliveira Lira, C. A. B.; Khoury, H. J.

    2011-07-01

    Computational anthropomorphic human phantoms are useful tools developed for the calculation of absorbed or equivalent dose to radiosensitive organs and tissues of the human body. The problem is, however, that, strictly speaking, the results can be applied only to a person who has the same anatomy as the phantom, while for a person with different body mass and/or standing height the data could be wrong. In order to improve this situation for many areas in radiological protection, this study developed 18 anthropometric standing adult human phantoms, nine models per gender, as a function of the 10th, 50th and 90th mass and height percentiles of Caucasian populations. The anthropometric target parameters for body mass, standing height and other body measures were extracted from PeopleSize, a well-known software package used in the area of ergonomics. The phantoms were developed based on the assumption of a constant body-mass index for a given mass percentile and for different heights. For a given height, increase or decrease of body mass was considered to reflect mainly the change of subcutaneous adipose tissue mass, i.e. that organ masses were not changed. Organ mass scaling as a function of height was based on information extracted from autopsy data. The methods used here were compared with those used in other studies, anatomically as well as dosimetrically. For external exposure, the results show that equivalent dose decreases with increasing body mass for organs and tissues located below the subcutaneous adipose tissue layer, such as liver, colon, stomach, etc, while for organs located at the surface, such as breasts, testes and skin, the equivalent dose increases or remains constant with increasing body mass due to weak attenuation and more scatter radiation caused by the increasing adipose tissue mass. Changes of standing height have little influence on the equivalent dose to organs and tissues from external exposure. Specific absorbed fractions (SAFs) have also

  20. Preparation and Characterization of a Monoclonal Antibody Against the Core Protein VP7 of the 25th Serotype of Bluetongue Virus

    PubMed Central

    Wu, Xiao; Liu, Qi; He, Jia; Zang, Mingxin; Wang, Haixiu; Li, Yijing

    2015-01-01

    Bluetongue virus (BTV) is a member of the genus Orbivirus, within the family Reoviridae. The VP7 protein of BTV is used for developing group-specific serological assays. To prepare monoclonal antibody (MAb) against VP7 of the 25th serotype BTV, the RNA S7 encoding VP7 was cloned into prokaryotic expression vectors pET-28a (+) and pGEX-6P-1 to generate recombinant plasmids. The recombinant protein VP7 was expressed in Escherichia coli BL21 (DE3), respectively. The results of SDS-PAGE revealed that the VP7 was expressed and the molecular mass of recombinant fusion protein pET-28a (+)/VP7 and pGEX-6P-1/VP7 was approximately 44 kDa and 64 kDa, respectively. The Western blot analysis indicated that the recombinant VP7 possessed good immunoreactivity. After purification, pET-28a (+)/VP7 was used to immunize BALB/c mice, while pGEX-6P-1/VP7 was used to screen for well-to-well MAb-secreting hybridomas. The hybridoma cell line 3H7 against recombinant VP7 that secreted MAbs was obtained. The isotype of 3H7 was identified as IgG1. The purification of recombinant VP7 protein and the monoclonal antibody will have potential applications on competitive ELISA format for BT-specific serum detection method. PMID:25897610

  1. Preparation and Characterization of a Monoclonal Antibody Against the Core Protein VP7 of the 25th Serotype of Bluetongue Virus.

    PubMed

    Wu, Xiao; Liu, Qi; He, Jia; Zang, Mingxin; Wang, Haixiu; Li, Yijing; Tang, Lijie

    2015-04-01

    Bluetongue virus (BTV) is a member of the genus Orbivirus, within the family Reoviridae. The VP7 protein of BTV is used for developing group-specific serological assays. To prepare monoclonal antibody (MAb) against VP7 of the 25th serotype BTV, the RNA S7 encoding VP7 was cloned into prokaryotic expression vectors pET-28a (+) and pGEX-6P-1 to generate recombinant plasmids. The recombinant protein VP7 was expressed in Escherichia coli BL21 (DE3), respectively. The results of SDS-PAGE revealed that the VP7 was expressed and the molecular mass of recombinant fusion protein pET-28a (+)/VP7 and pGEX-6P-1/VP7 was approximately 44 kDa and 64 kDa, respectively. The Western blot analysis indicated that the recombinant VP7 possessed good immunoreactivity. After purification, pET-28a (+)/VP7 was used to immunize BALB/c mice, while pGEX-6P-1/VP7 was used to screen for well-to-well MAb-secreting hybridomas. The hybridoma cell line 3H7 against recombinant VP7 that secreted MAbs was obtained. The isotype of 3H7 was identified as IgG1. The purification of recombinant VP7 protein and the monoclonal antibody will have potential applications on competitive ELISA format for BT-specific serum detection method. PMID:25897610

  2. Informing Policy and Practice in Australia's Vocational Education and Training Sector: Reflections and Futures. Proceedings of the 25th Anniversary Forum of the National Centre for Vocational Education Research (Adelaide, South Australia, Australia, March 21, 2007)

    ERIC Educational Resources Information Center

    Curtin, Penelope, Ed.; Loveder, Phil, Ed.

    2007-01-01

    To mark the occasion of its 25th anniversary, the National Centre for Vocational Education Research (NCVER) brought together policy, industry and academic leaders to reflect on the role that research and statistics have played in the development of Australia's vocational education and training (VET) sector. This publication includes the original…

  3. Graduate Education--Past--Present--Future. Proceedings of the Annual Meeting of the Council of Graduate Schools in the United States (25th, Anaheim, California, December 11-14, 1985).

    ERIC Educational Resources Information Center

    Khalil, Edna M., Ed.

    This proceedings document contains papers presented at the 25th anniversary meeting of the Council of Graduate Schools in the United States (CGS); information on the CGS business meeting, notices of awards presentations, copies of the CGS constitution and bylaws, and a CGS membership list. Topics and presenters are as follows: "Current Issues in…

  4. The Human Face of Technological Change. Theme Papers from the Silver Jubilee Conference of the Australian College of Education (25th, Australian Capital Territory, Canberra, May 5-9, 1984).

    ERIC Educational Resources Information Center

    Randell, Shirley, Ed.

    Papers presented at the 25th annual conference of the Australia College of Education addressed four major themes: The Brave New World of 1984; The Communications Revolution; Being Human in a Technological Age; and Implications of the Technological Society of Education. Papers in this volume include: (1) "The Challenge of Education in the Brave New…

  5. Children's Rights and School Psychology: An Introduction to the Multiple Journal Series Honoring the 25th Anniversary of the United Nations Convention on the Rights of the Child

    ERIC Educational Resources Information Center

    Mcloughlin, Caven S.; Hart, Stuart N.

    2014-01-01

    This year, 2014, is the 25th anniversary of the United Nations Convention on the Rights of the Child--the world's "positive ideology" and its clearest statement of commitments to and respect and aspirations for the dignity of the child. To commemorate this landmark, a program of articles by respected experts has been organized to…

  6. The Quest for Excellence in Teacher Education. International Perspectives on Improving the Quality of Teacher Education. Proceedings of the World Assembly of the International Council on Education for Teaching (25th, Rio de Janeiro, Brazil, July 24-28, 1978).

    ERIC Educational Resources Information Center

    Leavitt, Howard B., Ed.; Klassen, Frank H., Ed.

    This document contains the proceedings of the 25th World Assembly of the International Council on Education for Teaching. The Assembly focused on the topic of improving teacher education on a global scale. Leading educators from every continent participated in workshops, plenary sessions, and group discussions on a variety of topics dealing with…

  7. Mathematics Education in the South Pacific. Proceedings of the Annual Conference of the Mathematics Education Research Group of Australasia Incorporated (25th, Auckland, New Zealand, July 7-10, 2002). Volume I [and] Volume II.

    ERIC Educational Resources Information Center

    Barton, Bill, Ed.; Irwin, Kathryn C., Ed.; Pfannkuch, Maxine, Ed.; Thomas, Michael O. J., Ed.

    This document contains the proceedings of the 25th annual conference of the Mathematics Education Research Group of Australia (MERGA) held at the University of Auckland, New Zealand. The focus of this meeting is mathematics education in the South Pacific. Presentations are centered around the topic of numeracy in primary or elementary school.…

  8. An inflatable belt system in the rear seat occupant environment: investigating feasibility and benefit in frontal impact sled tests with a 50th percentile male ATD

    PubMed Central

    Forman, Jason L.; Lopez-Valdes, Francisco J.; Dennis, Nate; Kent, Richard W.; Tanji, Hiromasa; Higuchi, Kazuo

    2010-01-01

    Frontal-impact airbag systems have the potential to provide a benefit to rear seat occupants by distributing restraining forces over the body in a manner not possible using belts alone. This study sought to investigate the effects of incorporating a belt-integrated airbag (“airbelt”) into a rear seat occupant restraint system. Frontal impact sled tests were performed with a Hybrid III 50th percentile male anthropomorphic test device (ATD) seated in the right-rear passenger position of a 2004 mid-sized sedan buck. Tests were performed at 48 km/h (20 g, 100 ms acceleration pulse) and 29 km/h (11 g, 100 ms). The restraints consisted of a 3-point belt system with a cylindrical airbag integrated into the upper portion of the shoulder belt. The airbag was tapered in shape, with a maximum diameter of 16 cm (at the shoulder) that decreased to 4 cm at the mid-chest. A 2.5 kN force-limiter was integrated into the shoulder-belt retractor, and a 2.3 kN pretensioner was present in the out-board anchor of the lap belt. Six ATD tests (three 48 km/h and three 29 km/h) were performed with the airbelt system. These were compared to previous frontal-impact, rear seat ATD tests with a standard (not-force-limited, not-pretensioned) 3-point belt system and a progressive force-limiting (peak 4.4 kN), pretensioning (FL+PT) 3-point belt system. In the 48 km/h tests, the airbelt resulted in significantly less (p<0.05, two-tailed Student’s t-test) posterior displacement of the sternum towards the spine (chest deflection) than both the standard and FL+PT belt systems (airbelt: average 13±1.1 mm standard deviation; standard belt: 33±2.3 mm; FL+PT belt: 23±2.6 mm). This was consistent with a significant reduction in the peak upper shoulder belt force (airbelt: 2.7±0.1 kN; standard belt: 8.7±0.3 kN; FL+PT belt: 4.4±0.1 kN), and was accompanied by a small increase in forward motion of the head (airbelt: 54±0.4 cm; standard belt: 45±1.3 cm; FL+PT belt: 47±1.1 cm) The airbelt system

  9. Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995–2011

    PubMed Central

    Peckham, Erin C.; Scheurer, Michael E.; Danysh, Heather E.; Lubega, Joseph; Langlois, Peter H.; Lupo, Philip J.

    2015-01-01

    There is warranted interest in assessing the association between residential radon exposure and the risk of childhood cancer. We sought to evaluate the association between residential radon exposure and the incidence of childhood lymphoma in Texas. The Texas Cancer Registry (n = 2147) provided case information for the period 1995–2011. Denominator data were obtained from the United States Census. Regional arithmetic mean radon concentrations were obtained from the Texas Indoor Radon Survey and linked to residence at diagnosis. Exposure was assessed categorically: ≤25th percentile (reference), >25th to ≤50th percentile, >50th to ≤75th percentile, and >75th percentile. Negative binomial regression generated adjusted incidence rate ratios (aIRR) and 95% confidence intervals (CI). We evaluated lymphoma overall and by subtype: Hodgkin (HL; n = 1248), Non-Hodgkin excluding Burkitt (non-BL NHL; n = 658), Burkitt (BL; n = 241), and Diffuse Large B-cell (DLBCL; n = 315). There was no evidence that residential radon exposure was positively associated with lymphoma overall, HL, or BL. Areas with radon concentrations >75th percentile had a marginal increase in DLBCL incidence (aIRR = 1.73, 95% CI: 1.03–2.91). In one of the largest studies of residential radon exposure and the incidence of childhood lymphoma, we found little evidence to suggest a positive or negative association; an observation consistent with previous studies. PMID:26404336

  10. Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995-2011.

    PubMed

    Peckham, Erin C; Scheurer, Michael E; Danysh, Heather E; Lubega, Joseph; Langlois, Peter H; Lupo, Philip J

    2015-10-01

    There is warranted interest in assessing the association between residential radon exposure and the risk of childhood cancer. We sought to evaluate the association between residential radon exposure and the incidence of childhood lymphoma in Texas. The Texas Cancer Registry (n = 2147) provided case information for the period 1995-2011. Denominator data were obtained from the United States Census. Regional arithmetic mean radon concentrations were obtained from the Texas Indoor Radon Survey and linked to residence at diagnosis. Exposure was assessed categorically: ≤25th percentile (reference), >25th to ≤50th percentile, >50th to ≤75th percentile, and >75th percentile. Negative binomial regression generated adjusted incidence rate ratios (aIRR) and 95% confidence intervals (CI). We evaluated lymphoma overall and by subtype: Hodgkin (HL; n = 1248), Non-Hodgkin excluding Burkitt (non-BL NHL; n = 658), Burkitt (BL; n = 241), and Diffuse Large B-cell (DLBCL; n = 315). There was no evidence that residential radon exposure was positively associated with lymphoma overall, HL, or BL. Areas with radon concentrations >75th percentile had a marginal increase in DLBCL incidence (aIRR = 1.73, 95% CI: 1.03-2.91). In one of the largest studies of residential radon exposure and the incidence of childhood lymphoma, we found little evidence to suggest a positive or negative association; an observation consistent with previous studies. PMID:26404336

  11. Multidisciplinary approach for the study of an Egyptian coffin (late 22nd/early 25th dynasty): combining imaging and spectroscopic techniques.

    PubMed

    Bracci, S; Caruso, O; Galeotti, M; Iannaccone, R; Magrini, D; Picchi, D; Pinna, D; Porcinai, S

    2015-06-15

    This paper demonstrates that an educated methodology based on both non-invasive and micro invasive techniques in a two-step approach is a powerful tool to characterize the materials and stratigraphies of an Egyptian coffin, which was restored several times. This coffin, belonging to a certain Mesiset, is now located at the Museo Civico Archeologico of Bologna (inventory number MCABo EG 1963). Scholars attributed it to the late 22nd/early 25th dynasty by stylistic comparison. The first step of the diagnostic approach applied imaging techniques on the whole surface in order to select measurements spots and to unveil both original and restored areas. Images and close microscopic examination of the polychrome surface allowed selecting representative areas to be investigated in situ by portable spectroscopic techniques: X-ray Fluorescence (XRF), Fiber Optic Reflectance Spectroscopy (FORS) and Fourier Transform Infrared spectroscopy (FTIR). After the analysis of the results coming from the first step, very few selected samples were taken to clarify the stratigraphy of the polychrome layers. The first step, based on the combination of imaging and spectroscopic techniques in a totally non-invasive modality, is quite unique in the literature on Egyptian coffins and enabled us to reveal many differences in the ground layer's composition and to identify a remarkable number of pigments in the original and restored areas. This work offered also a chance to check the limitations of the non-invasive approach applied on a complex case, namely the right localization of different materials in the stratigraphy and the identification of binding media. Indeed, to dissolve any remaining doubts on superimposed layers belonging to different interventions, it was necessary to sample few micro-fragments in some selected areas and analyze them prepared as cross-sections. The original ground layer is made of calcite, while the restored areas show the presence of either a mixture of calcite

  12. Multidisciplinary approach for the study of an Egyptian coffin (late 22nd/early 25th dynasty): Combining imaging and spectroscopic techniques

    NASA Astrophysics Data System (ADS)

    Bracci, S.; Caruso, O.; Galeotti, M.; Iannaccone, R.; Magrini, D.; Picchi, D.; Pinna, D.; Porcinai, S.

    2015-06-01

    This paper demonstrates that an educated methodology based on both non-invasive and micro invasive techniques in a two-step approach is a powerful tool to characterize the materials and stratigraphies of an Egyptian coffin, which was restored several times. This coffin, belonging to a certain Mesiset, is now located at the Museo Civico Archeologico of Bologna (inventory number MCABo EG 1963). Scholars attributed it to the late 22nd/early 25th dynasty by stylistic comparison. The first step of the diagnostic approach applied imaging techniques on the whole surface in order to select measurements spots and to unveil both original and restored areas. Images and close microscopic examination of the polychrome surface allowed selecting representative areas to be investigated in situ by portable spectroscopic techniques: X-ray Fluorescence (XRF), Fiber Optic Reflectance Spectroscopy (FORS) and Fourier Transform Infrared spectroscopy (FTIR). After the analysis of the results coming from the first step, very few selected samples were taken to clarify the stratigraphy of the polychrome layers. The first step, based on the combination of imaging and spectroscopic techniques in a totally non-invasive modality, is quite unique in the literature on Egyptian coffins and enabled us to reveal many differences in the ground layer's composition and to identify a remarkable number of pigments in the original and restored areas. This work offered also a chance to check the limitations of the non-invasive approach applied on a complex case, namely the right localization of different materials in the stratigraphy and the identification of binding media. Indeed, to dissolve any remaining doubts on superimposed layers belonging to different interventions, it was necessary to sample few micro-fragments in some selected areas and analyze them prepared as cross-sections. The original ground layer is made of calcite, while the restored areas show the presence of either a mixture of calcite

  13. PREFACE: 11th Asia-Pacific Conference on Plasma Science and Technology (APCPST-11) and 25th Symposium on Plasma Science for Materials (SPSM-25)

    NASA Astrophysics Data System (ADS)

    Watanabe, Takayuki; Kaneko, Toshio; Sekine, Makoto; Tanaka, Yasunori

    2013-06-01

    The 11th Asia-Pacific Conference on Plasma Science and Technology (APCPST-11) was held in Kyoto, Japan on 2-5 October 2012 with the 25th Symposium on Plasma Science for Materials (SPSM-25). SPSM has been held annually since 1988 under the sponsorship of The 153rd Committee on Plasma Materials Science, Japan Society for the Promotion of Science (JSPS). This symposium is one of the major activities of the Committee, which is organized by researchers in academia and industry for the purpose of advancing intersectional scientific information exchange and discussion of science and technology of plasma materials processing. APCPST and SPSM are jointly held biennially to survey the current status of low temperature and thermal plasma physics and chemistry for industrial applications. The whole area of plasma processing was covered from fundamentals to applications. Previous meetings were held in China, Japan, Korea, and Australia, attended by scientists from the Asia-Pacific and other countries. The joint conference was organized in plenary lectures, invited, contributed oral presentations and poster sessions. At this meeting, we had 386 participants from 10 countries and 398 presentations, including 26 invited presentations. This year, we arranged special topical sessions that covered green innovation, life innovation, and technical reports from industry. This conference seeks to bring the plasma community together and to create a forum for discussing the latest developments and issues, the challenges ahead in the field of plasma research and applications among engineers and scientists in Asia, the Pacific Rim, as well as Europe. This volume presents 44 papers that were selected via a strict peer-review process from full papers submitted for the proceedings of the conference. The topics range from the basic physics and chemistry of plasma processing to a broad variety of materials processing and environmental applications. This volume offers an overview of recent

  14. The effect of anatomical modeling on space radiation dose estimates: a comparison of doses for NASA phantoms and the 5th, 50th, and 95th percentile male and female astronauts

    NASA Astrophysics Data System (ADS)

    Bahadori, Amir A.; Van Baalen, Mary; Shavers, Mark R.; Dodge, Charles; Semones, Edward J.; Bolch, Wesley E.

    2011-03-01

    The National Aeronautics and Space Administration (NASA) performs organ dosimetry and risk assessment for astronauts using model-normalized measurements of the radiation fields encountered in space. To determine the radiation fields in an organ or tissue of interest, particle transport calculations are performed using self-shielding distributions generated with the computer program CAMERA to represent the human body. CAMERA mathematically traces linear rays (or path lengths) through the computerized anatomical man (CAM) phantom, a computational stylized model developed in the early 1970s with organ and body profiles modeled using solid shapes and scaled to represent the body morphometry of the 1950 50th percentile (PCTL) Air Force male. With the increasing use of voxel phantoms in medical and health physics, a conversion from a mathematical-based to a voxel-based ray-tracing algorithm is warranted. In this study, the voxel-based ray tracer (VoBRaT) is introduced to ray trace voxel phantoms using a modified version of the algorithm first proposed by Siddon (1985 Med. Phys. 12 252-5). After validation, VoBRAT is used to evaluate variations in body self-shielding distributions for NASA phantoms and six University of Florida (UF) hybrid phantoms, scaled to represent the 5th, 50th, and 95th PCTL male and female astronaut body morphometries, which have changed considerably since the inception of CAM. These body self-shielding distributions are used to generate organ dose equivalents and effective doses for five commonly evaluated space radiation environments. It is found that dosimetric differences among the phantoms are greatest for soft radiation spectra and light vehicular shielding.

  15. Stream flow changes across North Carolina (USA) 1955-2012 with implications for environmental flow management

    NASA Astrophysics Data System (ADS)

    Meitzen, Kimberly M.

    2016-01-01

    This study examines changes in stream flow conditions across North Carolina, relates these changes to geomorphological conditions of rivers, and makes recommendations for environmental flow guidelines to conserve and protect riverine ecosystems. Monthly stream flow percentile metrics (90th, 75th, 50th, 25th, and 10th percentiles) are compared over two time periods (1955-1980 and 1984-2012) for 63 gages distributed statewide. The results showed that stream flow changes vary spatially by flow magnitude, ecoregion, basin, and temporally by months. The greatest changes involve decreases to the 10th, 25th, 50th, and 75th percentiles and the least amount of change is associated with 90th percentile flows. The spring and summer months of February through August have the greatest flow reductions, while September, November, and December exhibit magnitude increases for the 75th and 90th percentile flows. The Blue Ridge has the least amount of change, whereas the Piedmont and Coastal Plain have the greatest change. The few gages that do not show significant magnitude decreases to the 10th percentile flow are below major dams on the Neuse, Cape Fear, and Roanoke rivers. These same dammed rivers exhibit increases to the 90th percentile flows. The Tar River Basin, which is free of dams, shows opposite effects, with significant decreases to the 10th percentile flows and minimal changes to the 75th and 90th percentile flows. This study elucidates the importance of establishing environmental flow criteria that apply statewide across North Carolina. Sustainable environmental flow criteria need to be established that conserve seasonal patterns of flows, sustain low flows (from increases and decreases), and protect headwater and tributary accumulation areas from over-abstraction.

  16. 50th anniversary of the laser

    NASA Astrophysics Data System (ADS)

    Bertolotti, M.

    2010-09-01

    On July, 7, 1960 a press conference at Huyghes announced that Maiman had assembled and put into operation the first laser. It was the very pulsed ruby laser that everybody knows today. The announcement came as a bomb. Nobody expected that in an unknown laboratory, new to the race to build a laser, this result could be obtained. It was such an unexpected result that many still today mantain that the true laser was discovered at Bell by Shawlow. This result was achieved through a long story which passed by the Townes maser and many tentative experiments and discussions both in the USA and Soviet Union. In this special issue we present a collection of papers which provide further information as to what happened after Einstein introduced the concept of stimulated emission. The first paper is a short paper by Townes on the development of the physics of microwaves following the creation of the maser. When the laser came on the stage one of its properties was the inherent coherence of the emitted light. Emil Wolf's contribution enlights the early days of coherence to which he so much contributed and the very timely first Rochester Conference which was held on June 27-29, 1960 a few days before the Times announcement of the Maiman achievement. Important contributions were given by Soviet Scientists and, Svetlana Lukishova's contributions helps us understand the work of Valentin Fabrikant which was mostly unknown to western scientists. At the end of his life, Maiman went to Vancouver in Canada and Andrew H. Rawicz gives his testimoniancy of his friendship there. Coherence and the statistical properties of laser light were much studied and we have two exceptional papers by Roy Pike and Jan Perina discussing these arguments. The issue also contains three more papers presenting some earlier achievements in the construction of multiquantumwell laser (M. L. Dotor, P. Huertas, P. A. Postigo, D. Golmayo and F. Briones), the first measurements on very short pulses (H. P. Weber and R. Dandliker) and spatial coherence (D. P. Barato and M. L. Calvo).

  17. 50th anniversary of the word "allosteric".

    PubMed

    Changeux, Jean-Pierre

    2011-07-01

    A brief historical account on the origin and meaning of the word "allosteric" is presented. The word was coined in an attempt to qualify the chemical mechanism of the feedback inhibition of bacterial enzymes by regulatory ligands. The data lead to the proposal that, at variance with the classical mechanism of mutual exclusion by steric hindrance, the inhibition takes place through an "allosteric" interaction between "no overlapping", stereospecifically distinct, sites for substrate and feedback inhibitor, mediated by a discrete reversible alteration of the molecular structure of the protein. PMID:21574197

  18. [Changes in heart rate variability after myocardial infarction. Value of Poincareé's diagram].

    PubMed

    Copie, X; Le Heuzey, J Y; Iliou, M C; Pousset, F; Lavergne, T; Guize, L

    1995-11-01

    The variability of the heart rate is reduced after myocardial infarction. It then progressively increases, to return to near normal values after several months. However, these changes in heart rate variability occur at the same time as slowing of the heart rate which makes interpretation difficult. Poincaré's diagram is constructed from a Holter recording plotting each RR interval against the preceding RR interval. The authors have developed a geometric approach to this diagram to evaluate parasympathetic tone for a given heart rate. By measuring the dispersion in height of the Poincaré's diagram, the authors evaluate the shor-term variability for a given RR interval. Two 24 hr Holter recordings were performed in 52 patients at one and two weeks after a myocardial infarction. The dispersion in the height of the Poincaré's diagrams was measured at the 10th, 25th, 50th, 75th and 90th percentiles of the total dispersion. The authors have shown an increase in the short-term variability of the shortest RR intervals (1th, 25th and 50th percentiles) which is not observed in the longer RR intervals (75th and 90th percentiles). In conclusion, theres is an increase in the heart rate variability at the shortest RR intervals. This suggests that the recovery of parasympathic tone after myocardial infarction occurs mainly at the fastest heart rates. PMID:8745997

  19. Changes of the transverse diameter and volume and dosimetry before the 25th fraction during the course of intensity-modulated radiation therapy (IMRT) for patients with nasopharyngeal carcinoma

    SciTech Connect

    Yang Haihua; Hu Wei; Ding Weijun; Shan Guoping; Wang Wei; Yu Changhui; Wang Biyun; Shao Minghai; Wang Jianhua; Yang Weifang

    2012-07-01

    To quantify changes of the transverse diameter and volume and dosimetry, and to illustrate the inferiority of non-replanning during intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC) patients. Fifty-three NPC patients who received IMRT in 33 fractions were enrolled in this prospective trial. Before the 25th fraction, a new simulation computed tomography (CT) scan was acquired for all patients. The dose-volume histograms of the phantom plan were compared with the initial plan. Significant reduction of the transverse diameter of the nasopharyngeal, the neck, and 2 parotid glands volume was observed on second CT compared with the first CT (mean reduction 7.48 {+-} 4.45 mm, 6.80 {+-} 15.14 mm, 5.70 {+-} 6.26 mL, and 5.04 {+-} 5.85 mL, respectively; p < 0.01). The maximum dose and V-40 of the spinal cord, mean dose, and V30 of the left and right parotid, and V-50 of the brain stem were increased significantly in the phantom plan compared with the initial plan (mean increase 4.75 {+-} 5.55 Gy, 7.18 {+-} 10.07%, 4.51 {+-} 8.55 Gy, 6.59 {+-} 17.82%, 5.33 {+-} 8.55 Gy, 11.68 {+-} 17.11% and 1.48 {+-} 3.67%, respectively; p < 0.01). On the basis of dose constraint criterion in the RTOG0225 protocol, the dose of the normal critical structures for 52.83% (28/53) of the phantom plans were out of limit compared with 1.89% (1/53) of the initial plans (p < 0.0001). Because of the significant change in anatomy and dose before the 25th fraction during IMRT, replanning should be necessary during IMRT with NPC.

  20. Genomics in personalized cancer medicine and its impact on early drug development in China: report from the 6th Annual Meeting of the US Chinese Anti-Cancer Association (USCACA) at the 50th ASCO Annual Meeting.

    PubMed

    Zhang, Wei; Cheng, Shi-Yuan; Hou, Li-Fang; Yan, Li; Tong, Yun-Guang

    2014-08-01

    The 6th Annual Meeting of the United States Chinese Anti-Cancer Association (USCACA) was held in conjunction with the 50th Annual Meeting of American Society of Clinical Oncology (ASCO) on May 30, 2014 in Chicago, Illinois, the United States of America. With a focus on personalized medicine, the conference featured novel approaches to investigate genomic aberrations in cancer cells and innovative clinical trial designs to expedite cancer drug development in biomarker-defined patient populations. A panel discussion further provided in-depth advice on advancing development of personalized cancer medicines in China. The conference also summarized USCACA key initiatives and accomplishments, including two awards designated to recognize young investigators from China for their achievements and to support their training in the United States. As an effort to promote international collaboration, USCACA will team up with Chinese Society of Clinical Oncology (CSCO) to host a joint session on "Breakthrough Cancer Medicines" at the upcoming CSCO Annual Meeting on September 20th, 2014 in Xiamen, China. PMID:25096543

  1. The 2014 Surgeon General's report: commemorating the 50th Anniversary of the 1964 Report of the Advisory Committee to the US Surgeon General and updating the evidence on the health consequences of cigarette smoking.

    PubMed

    Alberg, Anthony J; Shopland, Donald R; Cummings, K Michael

    2014-02-15

    The question of whether cigarette smoking was associated with lung cancer was central to the expansion of epidemiology into the study of chronic diseases in the 1950s. The culmination of this era was the 1964 report of the Advisory Committee to the Surgeon General, a landmark document that included an objective synthesis of the evidence of the health consequences of smoking according to causal criteria. The report concluded that cigarette smoking was a cause of lung cancer in men and sufficient in scope that "remedial action" was warranted at the societal level. The 2014 Surgeon General's report commemorates the 50th anniversary of the 1964 report. The evidence on the health consequences of smoking has been updated many times in Surgeon General's reports since 1964. These have summarized our increasingly greater understanding of the broad spectrum of the deleterious health effects of exposure to tobacco smoke across most major organ systems. In turn, this evidence has been translated into tobacco control strategies implemented to protect the public's health. The Surgeon General report process is an enduring example of evidence-based public health in practice. Substantial progress has been made, but cigarette smoking remains one of the most pressing global health issues of our time. PMID:24436362

  2. Abdominal Organ Location, Morphology, and Rib Coverage for the 5th, 50th, and 95th Percentile Males and Females in the Supine and Seated Posture using Multi-Modality Imaging

    PubMed Central

    Hayes, Ashley R.; Gayzik, F. Scott; Moreno, Daniel P.; Martin, R. Shayn; Stitzel, Joel D.

    2013-01-01

    The purpose of this study was to use data from a multi-modality image set of males and females representing the 5th, 50th, and 95th percentile (n=6) to examine abdominal organ location, morphology, and rib coverage variations between supine and seated postures. Medical images were acquired from volunteers in three image modalities including Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and upright MRI (uMRI). A manual and semi-automated segmentation method was used to acquire data and a registration technique was employed to conduct a comparative analysis between abdominal organs (liver, spleen, and kidneys) in both postures. Location of abdominal organs, defined by center of gravity movement, varied between postures and was found to be significant (p=0.002 to p=0.04) in multiple directions for each organ. In addition, morphology changes, including compression and expansion, were seen in each organ as a result of postural changes. Rib coverage, defined as the projected area of the ribs onto the abdominal organs, was measured in frontal, lateral, and posterior projections, and also varied between postures. A significant change in rib coverage between postures was measured for the spleen and right kidney (p=0.03 and p=0.02). The results indicate that posture affects the location, morphology and rib coverage area of abdominal organs and these implications should be noted in computational modeling efforts focused on a seated posture. PMID:24406951

  3. The 25th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Twenty-two papers are documented regarding aeronautical and spacecraft hardware. Technological areas include actuators, latches, cryogenic mechanisms, vacuum tribology, bearings, robotics, ground support equipment for aerospace applications, and other mechanisms.

  4. Clinical association of baseline levels of conjugated dienes in low-density lipoprotein and nitric oxide with aggressive B-cell non-Hodgkin lymphoma and their relationship with immunoglobulins and Th1-to-Th2 ratio

    PubMed Central

    Haddouche, Mustapha; Meziane, Warda; Hadjidj, Zeyneb; Mesli, Naima; Aribi, Mourad

    2016-01-01

    Objective The aim of this study was to highlight the clinical association of baseline levels of conjugated dienes in low-density lipoprotein (LDL-BCD) and nitric oxide (NO) with immunoglobulins (Igs) and T helper (Th)1/Th2 ratio in patients with newly diagnosed B-cell non-Hodgkin lymphoma (NHL). Patients and methods Thirty-two newly diagnosed patients with aggressive B-cell NHL and 25 age-, sex-, and body-mass-index-matched healthy controls were randomly selected for a cross-sectional case–control study conducted at the Hematology Department of Tlemcen Medical Centre University (northwest of Algeria). Results Circulating levels of LDL-BCD and NO and those of IgA and IgM were significantly higher in patients than in controls. The levels of Th1/Th2 ratio and plasma total antioxidant capacity were significantly lower in patients compared with controls, while malondialdehyde and protein carbonyl levels were significantly higher in patients. B-cell NHL was significantly associated with high levels of LDL-BCD from 25th to 75th percentile (25th percentile: relative risk [RR] =2.26, 95% confidence interval [CI] 1.42–3.59, P=0.014; 50th percentile: RR =2.84, 95% CI 1.72–4.68, P<0.001; 75th percentile: RR =5.43, 95% CI 2.58–11.42, P<0.001). Similarly, the disease was significantly associated with high levels of NO production from 25th to 75th percentile (25th percentile: RR =2.07, 95% CI 1.25–3.44, P=0.024; 50th percentile: RR =2.78, 95% CI 1.63–4.72, P<0.001; 75th percentile: RR =4.68, 95% CI 2.21–9.91, P<0.001). Moreover, LDL-BCD levels were positively and significantly correlated with interferon (IFN)-γ, whereas NO levels were inversely and significantly correlated with IFN-γ and Th1/Th2 ratio. Conclusion LDL-BCD and NO production seem to be associated with aggressive B-cell NHL and alteration of Th1/Th2 ratio. Our results have to be examined using ex vivo mechanistic studies leading to further investigations of these parameters, with an interest in the

  5. Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday

    NASA Astrophysics Data System (ADS)

    Dowker, Fay; Elizalde, Emilio; Kirsten, Klaus

    2012-09-01

    extension that impacts particles never entering that region. What is the gravitational analogue for that situation? The analogue concerns the impact a localized curvature has, and the cone is an excellent example to shed light on that question. Related to the method of images, Stuart has done an enormous amount of work on the influence of topology and curvature on quantum field theory. An example is [17], where the vacuum stress-energy tensor for Clifford-Klein forms of the flat or spherical type were computed. Another strand we would like to mention is Stuart's interest in higher spin equations. In [18], Steven Weinberg wrote down a set of higher spin equations that took his fancy. They involved angular momentum theory, which has always pleased Stuart, and the description was an alternative to Roger Penrose's use of two-spinors. Investigating the inconsistencies that arose on coupling to gauge theories, Stuart extended the classic results in [19], from electromagnetism to gravity in accordance with his general philosophy; see, e.g., [20, 21, 22]. Lately, Stuart is best known for his many applications in the context of zeta function regularization and its applications to quantum field theory under external conditions and spectral theory. He can be considered the world expert on particular case calculations with a knowledge of the literature, old and recent, that is not seen very often and which originated in the many hours spent at different (mostly British) libraries. His attitude towards explicit computations is nicely summarized by himself: 'I have always been interested in exact solutions, even if unphysical, so long as they are pretty. They seem to be working mechanisms that fit together, complete in themselves, like a watch.' The following issue in honour of Stuart's 75th birthday contains contributions that touch upon the various topics he has worked on. References [1] de Broglie L 1928 La mécanique ondulatoire (Paris: Gauthier-Villars) [2] Castillejo L, Dalitz R H

  6. Report on the 5‘th scientific meeting of the “Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie” (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th – Oct. 27th, 2013

    PubMed Central

    2013-01-01

    From october 25th - 27th 2013, the 5th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. This year more than 60 doctoral students and postdocs from over 25 different groups working in German university hospitals or research institutes attended the meeting to discuss their latest findings in the fields of neuroimmunology, neurodegeneration and neurovascular research. All participants appreciated the stimulating environment in Motzen, Brandenburg, and people took the opportunity for scientific exchange, discussion about ongoing projects and already started further collaborations. Like in the previous years, the symposium was regarded as a very well organized platform to support research of young investigators in Germany. According to the major aim of NEUROWIND e.V. to support younger researchers in Germany the 3rd NEUROWIND YOUNG SCIENTIST AWARD for experimental neurology was awarded to Ruth Stassart working in the group of Klaus Armin Nave and Wolfgang Brück (MPI Göttingen and Department of Neuropathology, Göttingen Germany). The successful work was published in Nature Neuroscience entitled “A role for Swann cell-derived neuregulin-1 in remyelination”. This outstanding paper deals with the function of Schwann cell neuregulin as an endogenous factor for myelin repair. The award is endowed with 20.000 Euro sponsored by Merck Serono GmbH, Darmstadt, Germany (unrestricted educational grant). This year’s keynote lecture was given by Albert Ludolph, Head of the Department of Neurology at the University Clinic of Ulm. Dr. Ludolph highlighted the particular role of individual scientists for the development of research concepts in Alzheimer´s disease (AD) and frontotemporal dementia (FTD). PMID:24330587

  7. CONFERENCES AND SYMPOSIA: On the 50th anniversary of the L F Vereshchagin Institute for High Pressure Physics, RAS (Scientific outreach session of the Physical Sciences Division of the Russian Academy of Sciences, 23 April 2008)

    NASA Astrophysics Data System (ADS)

    Stishov, S. M.; Khvostantsev, L. G.; Slesarev, V. N.; Popova, S. V.; Brazhkin, V. V.; Dyuzheva, T. I.; Dzhavadov, L. N.; Gromnitskaya, E. L.; Stepanov, G. N.; Timofeev, Yu A.; Dizhur, E. M.; Venttsel, V. A.; Voronovskii, A. N.; Ryzhov, V. N.; Barabanov, A. F.; Magnitskaya, M. V.; Tareeva, E. E.

    2008-10-01

    A scientific outreach session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) was held on 23 April 2008 at the Institute for High Pressure Physics, RAS, Troitsk, Moscow region. The session was devoted to the 50th anniversary of the Institute. The following reports were presented: (1) Stishov S M (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "The Institute for High Pressure Physics is now 50 (opening address)"; (2) Khvostantsev L G and Slesarev V N (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Large-volume high-pressure devices for physical investigations"; (3) Popova S V, Brazhkin V V and Dyuzheva T I (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Structural phase transitions in highly compressed substances and the synthesis of high-pressure phases"; (4) Dzhavadov L N, Gromnitskaya E L, Stepanov G N and Timofeev Yu A (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Studies of the thermodynamic, elastic, superconducting, and magnetic properties of substances at high pressures"; (5) Dizhur E M, Venttsel V A and Voronovskii A N (Institute for High Pressure Physics, RAS, Troitsk, Moscow region), "Quantum transport at high pressures"; (6) Ryzhov V N, Barabanov A F, Magnitskaya M V and Tareyeva E E (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Theoretical studies of condensed matter"; (7) Bugakov V I, Antanovich A A, Konyaev Yu S and Slesarev V N (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Designing new construction and superhard materials and related tools." An abridged version of reports 1 -6 is presented below. • The Institute for High Pressure Physics is now 50 (opening address), Stishov S M Physics-Uspekhi, 2008, Volume 51, Number 10, Pages 1055-1059 • Large-volume high-pressure devices for physical investigations, Khvostantsev L G and Slesarev V N Physics-Uspekhi, 2008, Volume 51, Number 10, Pages 1059

  8. Reliable radiogenic heat production of representative lithological groups

    NASA Astrophysics Data System (ADS)

    Vilà, Miquel; Fernández, Manel

    2010-05-01

    Determining the temperature distribution within the lithosphere requires the knowledge of the radiogenic heat production (RHP) distribution within the crust and the lithospheric mantle. RHP of crustal rocks varies considerably at different scales as a result of the petrogenetic processes responsible for their formation and therefore RHP depends on the considered lithologies. In this work we address RHP variability of some common lithological groups from a compilation of a total of 2188 representative U, Th and K concentrations of different worldwide rock types derived from 102 geochemical and geophysical datasets previously published. To optimize the use of the generated RHP database we have classified and renamed the rock-type denominations of the original works following a petrologic classification scheme with a hierarchical structure. To compute RHP a reasonable average density was assigned for each lithologic group. The RHP data of each lithological group is presented in cumulative distribution plots, and we report a table with the mean, the standard deviation, the minimum and maximum values, and the significant percentiles (10th, 25th, 50th, 75th and 90th) of these lithological groups. In general, for each lithological group exists a wide zone around the median value with a constant slope indicating RHP values with the same probability of occurrence. This zone usually includes the RHP range defined by the 25th and the 75th percentile. When compare previuos RHP estimates of representative lithological groups with our results it is observed that most of them fall between the 25th and 75th percentiles obtained. We integrate our results in a schematic model of the differentiation processes undergone by lithospheric rocks. This model allows us to discuss the RHP variability for the different igneous, sedimentary and metamorphic lithological groups from a petrogenetic viewpoint. Finally we give some useful guidelines to assign RHP values to lithospheric thermal

  9. 75th anniversary of the N V Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN) (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 25 February 2015)

    NASA Astrophysics Data System (ADS)

    2015-06-01

    A scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) celebrating the 75th anniversary of the N V Pushkov Institute of Terrestrial Magnetism, Ionosphere, and Radio Wave Propagation of the RAS (IZMIRAN) was held in the IZMIRAN conference hall on 25 February 2015. The agenda of the session announced on the website http://www.gpad.ac.ru of the RAS Physical Sciences Division contained the following reports: (1) Kuznetsov V D (IZMIRAN, Moscow) "N V Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN) yesterday, today, and tomorrow"; (2) Gvishiani A D (Geophysical Center, Moscow) "Studies of the terrestrial magnetic field and the network of Russian magnetic laboratories"; (3) Sokoloff D D (Faculty of Physics, Lomonosov Moscow State University, Moscow) "Magnetic dynamo questions"; (4) Petrukovich A A (Space Research Institute, RAS, Moscow) "Some aspects of magnetosphere-ionosphere relations"; (5) Lukin D S (Moscow Institute of Physics and Technology (State University), Dolgoprudnyi, Moscow region) "Current problems of ionospheric radio wave propagation"; (6) Safargaleev V V (Polar Geophysical Institute, Kola Scientific Center, RAS, Murmansk), Sergienko T I (Swedish Institute of Space Physics (IRF), Sweden), Kozlovskii A E (Sodankyl \\ddot a Geophysical Observatory, Finland), Safargaleev A V (St. Petersburg State University, St. Petersburg), Kotikov A L (St. Petersburg Branch of IZMIRAN, St. Petersburg) "Magnetic and optical measurements and signatures of reconnection in the cusp and vicinity"; (7) Kuznetsov V D (IZMIRAN, Moscow) "Space solar research: achievements and prospects". Papers written on the basis of oral reports 1, 3, 4, 6, and 7 are given below. • N V Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN) yesterday, today, tomorrow, V D Kuznetsov Physics-Uspekhi, 2015

  10. PREFACE: SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor: Devoted to the 75th anniversary of Yu M Ostanevich's birth

    NASA Astrophysics Data System (ADS)

    Gordely, Valentin; Kuklin, Alexander; Balasoiu, Maria

    2012-03-01

    The Second International Workshop 'SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor', devoted to the 75th anniversary of the birth of Professor Yu M Ostanevich (1936-1992), an outstanding neutron physicist and the founder of small-angle neutron scattering (field, group, and instrument) at JINR FLNPh, was held on 27-30 May at the Frank Laboratory of Neutron Physics. The first Workshop was held in October 2006. Research groups from different neutron centers, universities and research institutes across Europe presented more than 35 oral and poster presentations describing scientific and methodological results. Most of them were obtained with the help of the YuMO instrument before the IBR-2 shutdown in 2006. For the last four years the IBR-2 reactor has been shut down for refurbishment. At the end of 2010 the physical launch of the IBR-2M reactor was finally realized. Nowadays the small-angle neutron scattering (SANS) technique is applied to a wide range of scientific problems in condensed matter, soft condensed matter, biology and nanotechnology, and despite the fact that there are currently over 30 SANS instruments in operation worldwide at both reactor and spallation sources, the demand for beam-time is considerably higher than the time available. It must be remembered, however, that as the first SANS machine on a steady-state reactor was constructed at the Institute Laue Langevin, Grenoble, the first SANS instrument on a 'white' neutron pulsed beam was accomplished at the Joint Institute for Nuclear Research at the IBR-30 reactor, beamline N5. During the meeting Yu M Ostanevich's determinative and crucial contribution to the construction of spectrometers at the IBR-2 high-pulsed reactor was presented, as well as his contribution to the development of the time-of-flight (TOF) small-angle scattering technique, and a selection of other scientific areas. His leadership and outstanding scientific achievements in applications of the

  11. Optimal Skin-to-Stone Distance Is a Positive Predictor for Successful Outcomes in Upper Ureter Calculi following Extracorporeal Shock Wave Lithotripsy: A Bayesian Model Averaging Approach

    PubMed Central

    Cho, Kang Su; Jung, Hae Do; Ham, Won Sik; Chung, Doo Yong; Kang, Yong Jin; Jang, Won Sik; Kwon, Jong Kyou; Choi, Young Deuk; Lee, Joo Yong

    2015-01-01

    Objectives To investigate whether skin-to-stone distance (SSD), which remains controversial in patients with ureter stones, can be a predicting factor for one session success following extracorporeal shock wave lithotripsy (ESWL) in patients with upper ureter stones. Patients and Methods We retrospectively reviewed the medical records of 1,519 patients who underwent their first ESWL between January 2005 and December 2013. Among these patients, 492 had upper ureter stones that measured 4–20 mm and were eligible for our analyses. Maximal stone length, mean stone density (HU), and SSD were determined on pretreatment non-contrast computed tomography (NCCT). For subgroup analyses, patients were divided into four groups. Group 1 consisted of patients with SSD<25th percentile, group 2 consisted of patients with SSD in the 25th to 50th percentile, group 3 patients had SSD in the 50th to 75th percentile, and group 4 patients had SSD≥75th percentile. Results In analyses of group 2 patients versus others, there were no statistical differences in mean age, stone length and density. However, the one session success rate in group 2 was higher than other groups (77.9% vs. 67.0%; P = 0.032). The multivariate logistic regression model revealed that shorter stone length, lower stone density, and the group 2 SSD were positive predictors for successful outcomes in ESWL. Using the Bayesian model-averaging approach, longer stone length, lower stone density, and group 2 SSD can be also positive predictors for successful outcomes following ESWL. Conclusions Our data indicate that a group 2 SSD of approximately 10 cm is a positive predictor for success following ESWL. PMID:26659086

  12. Air Pollution and the Risk of Cardiac Defects: A Population-Based Case-Control Study.

    PubMed

    Hwang, Bing-Fang; Lee, Yungling Leo; Jaakkola, Jouni J K

    2015-11-01

    Previous epidemiologic studies have assessed the role of the exposure to ambient air pollution in the development of cardiac birth defects, but they have provided somewhat inconsistent results. To assess the associations between exposure to ambient air pollutants and the risk of cardiac defects, a population-based case-control study was conducted using 1087 cases of cardiac defects and a random sample of 10,870 controls from 1,533,748 Taiwanese newborns in 2001 to 2007.Logistic regression was performed to calculate odds ratios for 10 ppb increases in O3 and 10 μg/m increases in PM10. In addition, we compared the risk of cardiac defects in 4 categories-high exposure (>75th percentile); medium exposure (75th to 50th percentile); low exposure (<50th-25th percentile); reference (<25th percentile) based on the distribution of each pollutant. The risks of ventricular septal defects (VSD), atrial septal defects (ASD), and patent ductus arteriosus (PDA) were associated with 10 ppb increases in O3 exposure during the first 3 gestational months among term and preterm babies. In comparison between high PM10 exposure and reference category, there were statistically significant elevations in the effect estimates of ASD for all and terms births. In addition, there was a negative or weak association between SO2, NO2, CO, and cardiac defects.The study proved that exposure to outdoor air O3 and PM10 during the first trimester of gestation may increase the risk of VSD, ASD, and PDA. PMID:26554783

  13. UConn Hosts IACLEA for 50th Annual Conference

    ERIC Educational Resources Information Center

    Hudd, Robert S.

    2008-01-01

    The decision that led to the 1992 opening of the University of Connecticut's new public safety complex was excellent timing. Three years after the complex opened, complete with a state-of-the-art Public Safety Answering Point (PSAP), an emergency operations/training center and an indoor firing range, the quiet, nearly 4,000-acre UConn campus…

  14. 'Focus on Marshall' Marks Milestone With 50th Episode

    NASA Video Gallery

    Hard to believe, but it's been five years since the Marshall Space Flight Center began a video program called "Focus on Marshall." In those five years, co-hosts Bill Hubscher and Lori Meggs, have t...

  15. Fracture faces of frozen membranes: 50th anniversary

    PubMed Central

    Branton, Daniel

    2016-01-01

    In 1961, the development of an improved freeze-etching (FE) procedure to prepare rapidly frozen biological cells or tissues for electron microscopy raised two important questions. How does a frozen cell membrane fracture? What do the extensive face views of the cell’s membranes exposed by the fracture process of FE tell us about the overall structure of biological membranes? I discovered that all frozen membranes tend to split along weakly bonded lipid bilayers. Consequently, the fracture process exposes internal membrane faces rather than either of the membrane’s two external surfaces. During etching, when ice is allowed to sublime after fracturing, limited regions of the actual membrane surfaces are revealed. Examination of the fractured faces and etched surfaces provided strong evidence that biological membranes are organized as lipid bilayers with some proteins on the surface and other proteins extending through the bilayer. Membrane splitting made it possible for electron microscopy to show the relative proportion of a membrane’s area that exists in either of these two organizational modes. PMID:26823391

  16. The Classic Guide to Better Writing. 50th Anniversary Edition.

    ERIC Educational Resources Information Center

    Flesch, Rudolf; Lass, A. H.

    This handbook, first published 50 years ago, is designed to teach individuals how to write more effectively. It offers step-by-step techniques and exercises to write simply, clearly, and correctly. New features in this edition of the handbook include contemporary examples, and guidelines for computer assisted research and writing and for…

  17. Fracture faces of frozen membranes: 50th anniversary.

    PubMed

    Branton, Daniel

    2016-02-01

    In 1961, the development of an improved freeze-etching (FE) procedure to prepare rapidly frozen biological cells or tissues for electron microscopy raised two important questions. How does a frozen cell membrane fracture? What do the extensive face views of the cell's membranes exposed by the fracture process of FE tell us about the overall structure of biological membranes? I discovered that all frozen membranes tend to split along weakly bonded lipid bilayers. Consequently, the fracture process exposes internal membrane faces rather than either of the membrane's two external surfaces. During etching, when ice is allowed to sublime after fracturing, limited regions of the actual membrane surfaces are revealed. Examination of the fractured faces and etched surfaces provided strong evidence that biological membranes are organized as lipid bilayers with some proteins on the surface and other proteins extending through the bilayer. Membrane splitting made it possible for electron microscopy to show the relative proportion of a membrane's area that exists in either of these two organizational modes. PMID:26823391

  18. 50th International Winter Meeting on Nuclear Physics

    NASA Astrophysics Data System (ADS)

    Unlike many workshops, the Bormio meeting does not focus on a single topic. Instead, the aim is to bring together researchers and students from related fields in subatomic physics. Addressed topics include hadron physics, heavy ion physics, nuclear astrophysics and nuclear structure, particle physics, detectors and future projects as well as applications of these fields. Review talks by more senior speakers as well as talks and posters presented by junior researchers are encouraged.

  19. History of aldosterone on its 50th birthday.

    PubMed

    Fiore, Cristina; Calò, Lorenzo A; Colombo, Lorenzo; Grimm, Clarence E; Armanini, Decio

    2006-01-01

    The paper describes the impact of mineralocorticoid substances on water regulation from Theophrastus (IV century B.C.) to Thomas Addison (1849). It also opens to the missed discovery of aldosterone of I.A. Macchi. PMID:16874725

  20. A 50th anniversary guidebook for the desert project

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Desert Project encompasses a 400 square mile areas studied by a team of soil scientists and geologists from 1957 to 1972. The project was staffed by personnel of the Soil Survey Investigations, U.S. Soil Conservation Service, and work was done in cooperation with the Agricultural Experiment Stat...

  1. Magnus Strandqvist: 50th anniversary of his doctoral thesis.

    PubMed

    Kajanti, M J

    1994-01-01

    This article is dedicated to Magnus Strandqvist's famous doctoral thesis "Studien über die kumulative Wirkung der Röntgenstrahlen bei Fraktionierung. Erfahrungen aus dem Radiumhemmet an 280 Haut- und Lippenkarzinomen" published in Acta Radiologica in 1944. After a short biography of Strandqvist some central points of his work and their influence on future development of modern radiotherapy are presented. PMID:7993639

  2. 76 FR 11933 - 50th Anniversary of the Peace Corps

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    .... (Presidential Sig.) [FR Doc. 2011-5031 Filed 3-2-11; 11:15 am] Billing code 3195-W1-P ... rededicate ourselves to fulfilling the dream and continuing the work of all those who aspire and yearn...

  3. PREFACE: 25th IUPAP Conference on Computational Physics (CCP2013)

    NASA Astrophysics Data System (ADS)

    Shchur, Lev N.; Barash, Lev Yu

    2014-05-01

    Participants of the XXV IUPAP Conference on Computational physics came to Moscow at the end of the August during a hot period. It was not a hot period because of the summer; in fact, the weather was quite comfortable. It was a hot period for the atmosphere amidst scientific society in Russia, especially for scientists working for the Russian Academy of Sciences. Four years ago, the C20 IUPAP Commission on Computational Physics and Computational Physics Group of the European Physical Society chose Moscow for several reasons. The first reason was connected to the high level and deep traditions of computational physics in Russia. It is known from experience at the former CCP conferences that native participants contribute about half of the presentations which form the solid scientific background of the conference, and the good level of domestic science makes the conference interesting and successful. The second reason was due to the fact that for the last twenty years there were not many IUPAP conferences in Russia, and it was a time to open more places for information exchange and intensify scientific collaboration. Thirdly, it was common opinion four years ago that the situation in Russia had become stable enough after the transition to a modern society, which took almost a quarter of a century. The conference preface is continued in the pdf.

  4. Proceedings of the 25th Project Integration Meeting

    NASA Technical Reports Server (NTRS)

    Phillips, M.

    1985-01-01

    Topics addressed include: silicon sheet growth and characterization, silicon material, process development, high-efficiency cells, environmental isolation, engineering sciences, and reliability physics.

  5. The Orphan Nuclear Receptors at Their 25th Year Reunion

    PubMed Central

    Mullican, Shannon E.; DiSpirito, Joanna R.; Lazar, Mitchell A.

    2013-01-01

    The Nuclear Receptor superfamily includes many receptors identified based on their similarity to steroid hormone receptors but without a known ligand. The study of how these receptors are diversely regulated to interact with genomic regions to control a plethora of biological processes has provided critical insight into development, physiology and the molecular pathology of disease. Here we provide a compendium of these so-called Orphan Receptors, and focus on what has been learned about their modes of action, physiological functions, and therapeutic promise. PMID:24096517

  6. 25th Anniversary Article: Supramolecular Materials for Regenerative Medicine

    PubMed Central

    Boekhoven, Job

    2014-01-01

    In supramolecular materials, molecular building blocks are designed to interact with one another via non-covalent interactions in order to create function. This offers the opportunity to create structures similar to those found in living systems that combine order and dynamics through the reversibility of intermolecular bonds. For regenerative medicine there is a great need to develop materials that signal cells effectively, deliver or bind bioactive agents in vivo at controlled rates, have highly tunable mechanical properties, but at the same time, can biodegrade safely and rapidly after fulfilling their function. These requirements make supramolecular materials a great platform to develop regenerative therapies. This review illustrates the emerging science of these materials and their use in a number of applications for regenerative medicine. PMID:24496667

  7. 25th ANNUAL NATIONAL CONFERENCE ON MANAGING ENVIRONMENTAL QUALITY SYSTEMS

    EPA Science Inventory

    The model results may help landscape ecologists produce indicators of surface water condition, such that unique combinations of these indicators can be used to infer the potential cause(s) and origin(s) of non-point pollution, which may lead to eutrophication in aquatic ecosystem...

  8. Naval Training Device Center 25th Anniversary Commemorative Technical Journal.

    ERIC Educational Resources Information Center

    Amico, G. Vincent; Regan, James J.

    Both the technical history of training devices and the issues which currently confront their design and use are discussed by a group of distinguished scientists and engineers. A blend of human factors and engineering paper reflects the twin thrusts that make up the educational tools that are training device systems. (Author)

  9. Proceedings, 25th international conference on ground control in mining

    SciTech Connect

    Peng, S.S.; Mark, C.; Finfinger, G.; Tadolini, S.; Wahab Khair, A.; Heasley, K.; Luo, Y.

    2006-07-01

    Topics covered include: computer and physical modelling; geology in ground control; geophysics in ground control; ground control; impoundments stability; longwall gateroad support design; longwall operations; longwall shields and standing supports; mine design; multiple-seam mining interactions; pillar and pillar extraction; roof bolting; roof bolting - resin; and subsidence. Most of the topics include a retrospective paper which summarises the progress of the subject field during the past 25 years.

  10. A method to assess the influence of individual player performance distribution on match outcome in team sports.

    PubMed

    Robertson, Sam; Gupta, Ritu; McIntosh, Sam

    2016-10-01

    This study developed a method to determine whether the distribution of individual player performances can be modelled to explain match outcome in team sports, using Australian Rules football as an example. Player-recorded values (converted to a percentage of team total) in 11 commonly reported performance indicators were obtained for all regular season matches played during the 2014 Australian Football League season, with team totals also recorded. Multiple features relating to heuristically determined percentiles for each performance indicator were then extracted for each team and match, along with the outcome (win/loss). A generalised estimating equation model comprising eight key features was developed, explaining match outcome at a median accuracy of 63.9% under 10-fold cross-validation. Lower 75th, 90th and 95th percentile values for team goals and higher 25th and 50th percentile values for disposals were linked with winning. Lower 95th and higher 25th percentile values for Inside 50s and Marks, respectively, were also important contributors. These results provide evidence supporting team strategies which aim to obtain an even spread of goal scorers in Australian Rules football. The method developed in this investigation could be used to quantify the importance of individual contributions to overall team performance in team sports. PMID:26853070

  11. Psychomotor development in Argentinean children aged 0-5 years.

    PubMed

    Lejarraga, Horacio; Pascucci, María Cecilia; Krupitzky, Sara; Kelmansky, Diana; Bianco, Ana; Martínez, Elena; Tibaldi, Fabián; Cameron, Noel

    2002-01-01

    In Argentina, there is no information on ages of attainment of developmental milestones and very few data about environmental factors that influence them. A national survey on the psychomotor development of children under 6 years of age was carried out with the help of 129 paediatricians. Logistic regression was applied to a final sample of 3573 healthy, normal children in order to estimate selected centiles (25th, 50th, 75th and 90th), together with their respective confidence intervals, of the ages of attainment of 78 developmental items belonging to the following areas: personal-social (18 items), fine motor (19), language (18) and gross motor (23). The 50th centile obtained for each of the 43 comparable items was compared with those obtained in previously standardised tests: DDST, Denver II, Bayley and Chilean scales. Neither significant nor systematic differences were found between our results and those described in the tests used for comparison. Multiple logistic regressions showed that social class, maternal education and sex (female) were associated with earlier attainment of some selected developmental items, achieved at ages later than 1 year. Selected items achieved before the first year of life were not affected by any of the independent environmental variables studied. The information is useful in helping paediatricians in their daily practice for surveillance of development, as baseline information for epidemiological studies on development in our country and for cross-cultural analysis. PMID:11856454

  12. Air Pollution and the Risk of Cardiac Defects

    PubMed Central

    Hwang, Bing-Fang; Lee, Yungling Leo; Jaakkola, Jouni J.K.

    2015-01-01

    Abstract Previous epidemiologic studies have assessed the role of the exposure to ambient air pollution in the development of cardiac birth defects, but they have provided somewhat inconsistent results. To assess the associations between exposure to ambient air pollutants and the risk of cardiac defects, a population-based case-control study was conducted using 1087 cases of cardiac defects and a random sample of 10,870 controls from 1,533,748 Taiwanese newborns in 2001 to 2007. Logistic regression was performed to calculate odds ratios for 10 ppb increases in O3 and 10 μg/m3 increases in PM10. In addition, we compared the risk of cardiac defects in 4 categories-high exposure (>75th percentile); medium exposure (75th to 50th percentile); low exposure (<50th–25th percentile); reference (<25th percentile) based on the distribution of each pollutant. The risks of ventricular septal defects (VSD), atrial septal defects (ASD), and patent ductus arteriosus (PDA) were associated with 10 ppb increases in O3 exposure during the first 3 gestational months among term and preterm babies. In comparison between high PM10 exposure and reference category, there were statistically significant elevations in the effect estimates of ASD for all and terms births. In addition, there was a negative or weak association between SO2, NO2, CO, and cardiac defects. The study proved that exposure to outdoor air O3 and PM10 during the first trimester of gestation may increase the risk of VSD, ASD, and PDA. PMID:26554783

  13. [Navy medical academy (to the 75th anniversary of establishment)].

    PubMed

    Chernikov, O G; Zaimagov, S V

    2016-02-01

    The article is devoted to the history of the creation in 1940 of the Naval Medical Academy on the basis of the 3rd Leningrad Medical Institute and the Institute for sanitary-chemical protection of the People's Commissariat of the USSR. The structure of this institution included, faculties management staff of the medical service, medical and sanitation, Higher Naval Medical School, the Marine Research Institute Medical, higher courses for officers of the medical service, clinical naval hospital. During the period of its activity (1940-1956), the staff of the Naval Medical Academy made a great contribution to the naval medicine and practical public health. The merit of the Academy is not only a beautifully staged academic, medical, research process, but also in the creation of the spirit of the high sea camaraderie, accomplishment and pride for the work which its graduates have dedicated their lives. PMID:27263215

  14. Biomechanics, Exercise Physiology, and the 75th Anniversary of RQES

    ERIC Educational Resources Information Center

    Hamill, Joseph; Haymes, Emily M.

    2005-01-01

    The purpose of this paper is to review the biomechanics and exercise physiology studies published in the Research Quarterly for Exercise and Sport (RQES) over the past 75 years. Studies in biomechanics, a relatively new subdiscipline that evolved from kinesiology, first appeared in the journal about 40 years ago. Exercise physiology studies have…

  15. The bright thread: the Bulletin's 75th anniversary.

    PubMed Central

    Beatty, W K

    1998-01-01

    This chronological review of the Bulletin of the Medical Library Association deals with the years 1911 through 1985. The Bulletin has had nineteen editors, from Marcia C. Noyes and John Ruhräh, M.D. (1911-26), through Susan Crawford, Ph.D. (1983-1986). This paper describes the Bulletin's gradual expansion in size and contents, the initiation of various departments and sections, and some of the pioneering articles. Major steps in expenses, income, and subscription price are given. Important changes in the format and the growth of the administrative and advisory structures are covered. Images PMID:9578946

  16. Percentile Distributions of Median Nitrite Plus Nitrate as Nitrogen, Total Nitrogen, and Total Phosphorus Concentrations in Oklahoma Streams, 1973-2001

    USGS Publications Warehouse

    Haggard, Brian E.; Masoner, Jason R.; Becker, Carol J.

    2003-01-01

    first, second, and third order streams with streams slopes greater than 17 feet per mile. Nitrite plus nitrate as nitrogen and total nitrogen criteria determined by the U.S. Environmental Protection Agency for the Ozark Highland ecoregion were less than the 25th percentiles of median nitrite plus nitrate as nitrogen, total nitrogen, and total phosphorus concentrations in the Ozark Highland ecoregion calculated for this report. Nitrite plus nitrate as nitrogen and total nitrogen criteria developed by the U.S. Environmental Protection Agency for the Ouachita Mountains ecoregion were similar to the 25th percentiles of median nitrite plus nitrate as nitrogen and total nitrogen concentrations in the Ouachita Mountains ecoregion calculated for this report. Nitrate as nitrogen and total phosphorus concentrations currently (2002) used in the Use Support Assessment Protocols for Oklahoma were greater than the 75th percentiles of median nitrite plus nitrate as nitrogen and total phosphorus concentrations calculated for this report.

  17. Relationships between atmospheric circulation indices and rainfall in Northern Algeria and comparison of observed and RCM-generated rainfall

    NASA Astrophysics Data System (ADS)

    Taibi, S.; Meddi, M.; Mahé, G.; Assani, A.

    2015-09-01

    This work aims, as a first step, to analyze rainfall variability in Northern Algeria, in particular extreme events, during the period from 1940 to 2010. Analysis of annual rainfall shows that stations in the northwest record a significant decrease in rainfall since the 1970s. Frequencies of rainy days for each percentile (5th, 10th, 25th, 50th, 75th, 90th, 95th, and 99th) and each rainfall interval class (1-5, 5-10, 10-20, 20-50, and ≥50 mm) do not show a significant change in the evolution of daily rainfall. The Tenes station is the only one to show a significant decrease in the frequency of rainy days up to the 75th percentile and for the 10-20-mm interval class. There is no significant change in the temporal evolution of extreme events in the 90th, 95th, and 99th percentiles. The relationships between rainfall variability and general atmospheric circulation indices for interannual and extreme event variability are moderately influenced by the El Niño-Southern Oscillation and Mediterranean Oscillation. Significant correlations are observed between the Southern Oscillation Index and annual rainfall in the northwestern part of the study area, which is likely linked with the decrease in rainfall in this region. Seasonal rainfall in Northern Algeria is affected by the Mediterranean Oscillation and North Atlantic Oscillation in the west. The ENSEMBLES regional climate models (RCMs) are assessed using the bias method to test their ability to reproduce rainfall variability at different time scales. The Centre National de Recherches Météorologiques (CNRM), Czech Hydrometeorological Institute (CHMI), Eidgenössische Technische Hochschule Zürich (ETHZ), and Forschungszentrum Geesthacht (GKSS) models yield the least biased results.

  18. Regression equations to estimate seasonal flow duration, n-day high-flow frequency, and n-day low-flow frequency at sites in North Dakota using data through water year 2009

    USGS Publications Warehouse

    Williams-Sether, Tara; Gross, Tara A.

    2016-01-01

    Seasonal mean daily flow data from 119 U.S. Geological Survey streamflow-gaging stations in North Dakota; the surrounding states of Montana, Minnesota, and South Dakota; and the Canadian provinces of Manitoba and Saskatchewan with 10 or more years of unregulated flow record were used to develop regression equations for flow duration, n-day high flow and n-day low flow using ordinary least-squares and Tobit regression techniques. Regression equations were developed for seasonal flow durations at the 10th, 25th, 50th, 75th, and 90th percent exceedances; the 1-, 7-, and 30-day seasonal mean high flows for the 10-, 25-, and 50-year recurrence intervals; and the 1-, 7-, and 30-day seasonal mean low flows for the 2-, 5-, and 10-year recurrence intervals. Basin and climatic characteristics determined to be significant explanatory variables in one or more regression equations included drainage area, percentage of basin drainage area that drains to isolated lakes and ponds, ruggedness number, stream length, basin compactness ratio, minimum basin elevation, precipitation, slope ratio, stream slope, and soil permeability. The adjusted coefficient of determination for the n-day high-flow regression equations ranged from 55.87 to 94.53 percent. The Chi2 values for the duration regression equations ranged from 13.49 to 117.94, whereas the Chi2 values for the n-day low-flow regression equations ranged from 4.20 to 49.68.

  19. Birthweight percentiles for twin birth neonates by gestational age in China.

    PubMed

    Zhang, Bin; Cao, Zhongqiang; Zhang, Yiming; Yao, Cong; Xiong, Chao; Zhang, Yaqi; Wang, Youjie; Zhou, Aifen

    2016-01-01

    Localized birthweight references for gestational ages serve as an essential tool in accurate evaluation of atypical birth outcomes. Such references for twin births are currently not available in China. The aim of this study was to construct up-to-data sex specific birth weight references by gestational ages for twin births in China. We conducted a population-based analysis on the data of 22,507 eligible living twin infants with births dated between 8/01/2006 and 8/31/2015 from all 95 hospitals within the Wuhan area. Gestational ages in complete weeks were determined using a combination of last-menstrual-period based (LMP) estimation and ultrasound examination. Smoothed percentile curves were created by the Lambda Mu Sigma (LMS) method. Reference of the 3(rd), 10(th), 25(th), 50(th), 75(th), 90(th), 97(th) percentiles birth weight by sex and gestational age were made using 11,861 male and 10,646 female twin newborns with gestational age 26-42 weeks. Separate birthweight percentiles curves for male and female twins were constructed. In summary, our study firstly presents percentile curves of birthweight by gestational age for Chinese twin neonates. Further research is required for the validation and implementation of twin birthweight curves into clinical practice. PMID:27506479

  20. Growth curves for school children from Kuching, Sarawak: a methodological development.

    PubMed

    Bong, Yii Bonn; Shariff, Asma Ahmad; Mohamed, Abdul Majid; Merican, Amir Feisal

    2015-03-01

    In this article, the authors propose reference curves for height and weight for school children in the Kuching area, Sarawak. The school children were from primary to secondary schools (aged 6.5 to 17 years old) and comprised both genders. Anthropometric measurements and demographic information for 3081 school-aged children were collected (1440 boys and 1641 girls). Fitted line plots and percentiles for height and weight (3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentiles) were obtained. The height of school boys and school girls were almost similar at the start of their school-going age. For school girls, height and weight values stabilized when they reached 16 or 17 years old but kept increasing for school boys. School boys were taller than school girls as they entered adolescence. Height differences between school boys and school girls became significantly wider as they grew older. Chinese school children were taller and heavier than those of other ethnic groups. PMID:22652249

  1. Multi-host model and threshold of intermediate host Oncomelania snail density for eliminating schistosomiasis transmission in China.

    PubMed

    Zhou, Yi-Biao; Chen, Yue; Liang, Song; Song, Xiu-Xia; Chen, Geng-Xin; He, Zhong; Cai, Bin; Yihuo, Wu-Li; He, Zong-Gui; Jiang, Qing-Wu

    2016-01-01

    Schistosomiasis remains a serious public health issue in many tropical countries, with more than 700 million people at risk of infection. In China, a national integrated control strategy, aiming at blocking its transmission, has been carried out throughout endemic areas since 2005. A longitudinal study was conducted to determine the effects of different intervention measures on the transmission dynamics of S. japonicum in three study areas and the data were analyzed using a multi-host model. The multi-host model was also used to estimate the threshold of Oncomelania snail density for interrupting schistosomiasis transmission based on the longitudinal data as well as data from the national surveillance system for schistosomiasis. The data showed a continuous decline in the risk of human infection and the multi-host model fit the data well. The 25th, 50th and 75th percentiles, and the mean of estimated thresholds of Oncomelania snail density below which the schistosomiasis transmission cannot be sustained were 0.006, 0.009, 0.028 and 0.020 snails/0.11 m(2), respectively. The study results could help develop specific strategies of schistosomiasis control and elimination tailored to the local situation for each endemic area. PMID:27535177

  2. Hydrologic data for the Larimer-Weld regional water-monitoring program, Colorado, 1975-82

    USGS Publications Warehouse

    Blakely, S.R.; Steinheimer, J.T.

    1984-01-01

    The Larimer-Weld, Colorado, regional Monitoring Program was begun in 1976 to provide information on the quality and quantity of the surface-water resources in the area. Three stations on the big Thompson River and five stations on the Cache La Poudre River were selected for a data-collection network. Four previously established stations were added to complete the data-collection network: Horsetooth Reservoir, Joe Wright Creek above and below Joe Wright Reservoir, and Michigan River near Cameron Pass. Station description, location, and period of record are given for each station. A statistical summary of the water-quality data for each station is tabulated. Frequency of occurrence is given at the 95th, 75th, 50th, and 25th percentiles. Monthly water-quality data and daily average streamflow data are tabulated for each streamflow station for which this data was collected; Monthly contents data are presented for Horsetooth Reservoir. All data tabulated and summarized are from the period October 1, 1975, through September 30, 1982. (USGS)

  3. Heavy metals in aquatic organisms of different trophic levels and their potential human health risk in Bohai Bay, China.

    PubMed

    Zhang, Yan; Lu, Xueqiang; Wang, Naili; Xin, Meinan; Geng, Shiwei; Jia, Jing; Meng, Qinghui

    2016-09-01

    Fourteen aquatic organism samples were collected from Bohai Bay, and concentrations of five heavy metals were measured to evaluate the pollution levels in aquatic organisms and the potential risk to human health. The concentrations of Zn and Cu were much higher than those of Cd, Cr, and Pb in all the organisms. In general, the heavy metal concentration levels were in the order phytoplankton < zooplankton < fish < shrimp < shellfish. Heavy metal concentrations in higher trophic-level aquatic organisms in Bohai Bay were compared to those in the organisms from other worldwide coastal waters. The concentration levels of most heavy metals were higher than the 75th percentile, except that Pb concentration was between the 25th and 50th percentiles. The calculated bioconcentration factors (BCF) of Cr, Cu, and Pb for phytoplankton were less than 100, indicating no accumulation in primary producers. The bioaccumulation factor (BAF) of Pb for zooplankton was the highest, indicating significant Pb accumulation in zooplankton. For higher trophic-level aquatic organisms, the order of BAF values was fish < shrimp < shellfish for most metals except for Pb. The human health risk assessment suggests that strict abatement measures of heavy metals must be taken to decrease the health risk caused by consuming aquatic products. PMID:27250089

  4. A Patient-Centered Electronic Tool for Weight Loss Outcomes after Roux-en-Y Gastric Bypass

    PubMed Central

    Gerhard, Glenn S.; Miller, Elaina K.; Zaccone, Richard J.; Argyropoulos, George A.; Petrick, Anthony T.; Still, Christopher D.

    2014-01-01

    Background. Current patient education and informed consent regarding weight loss expectations for bariatric surgery candidates are largely based on averages from large patient cohorts. The variation in weight loss outcomes illustrates the need for establishing more realistic weight loss goals for individual patients. This study was designed to develop a simple web-based tool which provides patient-specific weight loss expectations. Methods. Postoperative weight measurements after Roux-en-Y gastric bypass (RYGB) were collected and analyzed with patient characteristics known to influence weight loss outcomes. Quantile regression was used to create expected weight loss curves (25th, 50th, and 75th %tile) for the 24 months after RYGB. The resulting equations were validated and used to develop web-based tool for predicting weight loss outcomes. Results. Weight loss data from 2986 patients (2608 in the primary cohort and 378 in the validation cohort) were included. Preoperative body mass index (BMI) and age were found to have a high correlation with weight loss accomplishment (P < 0.0001 for each). An electronic tool was created that provides easy access to patient-specific, 24-month weight loss trajectories based on initial BMI and age. Conclusions. This validated, patient-centered electronic tool will assist patients and providers in patient teaching, informed consent, and postoperative weight loss management. PMID:24772350

  5. Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

    PubMed Central

    Darendeliler, Feyza; Yeşilkaya, Ediz; Bereket, Abdullah; Baş, Firdevs; Bundak, Rüveyde; Sarı, Erkan; Küçükemre Aydın, Banu; Darcan, Şükran; Dündar, Bumin; Büyükinan, Muammer; Kara, Cengiz; Mazıcıoğlu, Mümtaz M.; Adal, Erdal; Akıncı, Ayşehan; Atabek, Mehmet Emre; Demirel, Fatma; Çelik, Nurullah; Özkan, Behzat; Özhan, Bayram; Orbak, Zerrin; Ersoy, Betül; Doğan, Murat; Ataş, Ali; Turan, Serap; Gökşen, Damla; Tarım, Ömer; Yüksel, Bilgin; Ercan, Oya; Hatun, Şükrü; Şimşek, Enver; Ökten, Ayşenur; Abacı, Ayhan; Döneray, Hakan; Özbek, Mehmet Nuri; Keskin, Mehmet; Önal, Hasan; Akyürek, Nesibe; Bulan, Kezban; Tepe, Derya; Emeksiz, Hamdi Cihan; Demir, Korcan; Kızılay, Deniz; Topaloğlu, Ali Kemal; Eren, Erdal; Özen, Samim; Demirbilek, Hüseyin; Abalı, Saygın; Akın, Leyla; Eklioğlu, Beray Selver; Kaba, Sultan; Anık, Ahmet; Baş, Serpil; Ünüvar, Tolga; Sağlam, Halil; Bolu, Semih; Özgen, Tolga; Doğan, Durmuş; Çakır, Esra Deniz; Şen, Yaşar; Andıran, Nesibe; Çizmecioğlu, Filiz; Evliyaoğlu, Olcay; Karagüzel, Gülay; Pirgon, Özgür; Çatlı, Gönül; Can, Hatice Dilek; Gürbüz, Fatih; Binay, Çiğdem; Baş, Veysel Nijat; Sağlam, Celal; Gül, Davut; Polat, Adem; Açıkel, Cengizhan; Cinaz, Peyami

    2015-01-01

    Objective: Children with Turner syndrome (TS) have a specific growth pattern that is quite different from that of healthy children. Many countries have population-specific growth charts for TS. Considering national and ethnic differences, we undertook this multicenter collaborative study to construct growth charts and reference values for height, weight and body mass index (BMI) from 3 years of age to adulthood for spontaneous growth of Turkish girls with TS. Methods: Cross-sectional height and weight data of 842 patients with TS, younger than 18 years of age and before starting any therapy, were evaluated. Results: The data were processed to calculate the 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentile values for defined ages and to construct growth curves for height-for-age, weight-for-age and BMI-for-age of girls with TS. The growth pattern of TS girls in this series resembled the growth pattern of TS girls in other reports, but there were differences in height between our series and the others. Conclusion: This study provides disease-specific growth charts for Turkish girls with TS. These disease-specific national growth charts will serve to improve the evaluation of growth and its management with growth-promoting therapeutic agents in TS patients. PMID:26831551

  6. Birthweight percentiles for twin birth neonates by gestational age in China

    PubMed Central

    Zhang, Bin; Cao, Zhongqiang; Zhang, Yiming; Yao, Cong; Xiong, Chao; Zhang, Yaqi; Wang, Youjie; Zhou, Aifen

    2016-01-01

    Localized birthweight references for gestational ages serve as an essential tool in accurate evaluation of atypical birth outcomes. Such references for twin births are currently not available in China. The aim of this study was to construct up-to-data sex specific birth weight references by gestational ages for twin births in China. We conducted a population-based analysis on the data of 22,507 eligible living twin infants with births dated between 8/01/2006 and 8/31/2015 from all 95 hospitals within the Wuhan area. Gestational ages in complete weeks were determined using a combination of last-menstrual-period based (LMP) estimation and ultrasound examination. Smoothed percentile curves were created by the Lambda Mu Sigma (LMS) method. Reference of the 3rd, 10th, 25th, 50th, 75th, 90th, 97th percentiles birth weight by sex and gestational age were made using 11,861 male and 10,646 female twin newborns with gestational age 26–42 weeks. Separate birthweight percentiles curves for male and female twins were constructed. In summary, our study firstly presents percentile curves of birthweight by gestational age for Chinese twin neonates. Further research is required for the validation and implementation of twin birthweight curves into clinical practice. PMID:27506479

  7. Regression models for estimating herbicide concentrations in U.S. streams from watershed characteristics

    USGS Publications Warehouse

    Larson, S.J.; Gilliom, R.J.

    2001-01-01

    Regression models were developed for estimating stream concentrations of the herbicides alachlor, atrazine, cyanazine, metolachlor, and trifluralin from use-intensity data and watershed characteristics. Concentrations were determined from samples collected from 45 streams throughout the United States during 1993 to 1995 as part of the U.S. Geological Survey's National Water-Quality Assessment (NAWQA). Separate regression models were developed for each of six percentiles (10th, 25th, 50th, 75th, 90th, 95th) of the annual distribution of stream concentrations and for the annual time-weighted mean concentration. Estimates for the individual percentiles can be combined to provide an estimate of the annual distribution of concentrations for a given stream. Agricultural use of the herbicide in the watershed was a significant predictor in nearly all of the models. Several hydrologic and soil parameters also were useful in explaining the variability in concentrations of herbicides among the streams. Most of the regression models developed for estimation of concentration percentiles and annual mean concentrations accounted for 50 percent to 90 percent of the variability among streams. Predicted concentrations were nearly always within an order of magnitude of the measured concentrations for the model-development streams, and predicted concentration distributions reasonably matched the actual distributions in most cases. Results from application of the models to streams not included in the model development data set are encouraging, but further validation of the regression approach described in this paper is needed.

  8. Multi-host model and threshold of intermediate host Oncomelania snail density for eliminating schistosomiasis transmission in China

    PubMed Central

    Zhou, Yi-Biao; Chen, Yue; Liang, Song; Song, Xiu-Xia; Chen, Geng-Xin; He, Zhong; Cai, Bin; Yihuo, Wu-Li; He, Zong-Gui; Jiang, Qing-Wu

    2016-01-01

    Schistosomiasis remains a serious public health issue in many tropical countries, with more than 700 million people at risk of infection. In China, a national integrated control strategy, aiming at blocking its transmission, has been carried out throughout endemic areas since 2005. A longitudinal study was conducted to determine the effects of different intervention measures on the transmission dynamics of S. japonicum in three study areas and the data were analyzed using a multi-host model. The multi-host model was also used to estimate the threshold of Oncomelania snail density for interrupting schistosomiasis transmission based on the longitudinal data as well as data from the national surveillance system for schistosomiasis. The data showed a continuous decline in the risk of human infection and the multi-host model fit the data well. The 25th, 50th and 75th percentiles, and the mean of estimated thresholds of Oncomelania snail density below which the schistosomiasis transmission cannot be sustained were 0.006, 0.009, 0.028 and 0.020 snails/0.11 m2, respectively. The study results could help develop specific strategies of schistosomiasis control and elimination tailored to the local situation for each endemic area. PMID:27535177

  9. Individual estimation of exposures to extremely low frequency magnetic fields in jobs commonly held by women.

    PubMed

    Deadman, J E; Infante-Rivard, C

    2002-02-15

    Exposures to extremely low frequency (ELF) magnetic fields have not been documented extensively in occupations besides the work environments of electric or telephone utilities. A 1980-1993 study of childhood acute lymphoblastic leukemia (ALL) in Québec, Canada, gathered detailed information about the occupations of 491 mothers of ALL cases and mothers of a similar number of healthy controls. This information was combined with published data on the intensities of ELF magnetic fields associated with sources or work environments to estimate ELF magnetic field exposures for a wide range of jobs commonly held by women. Estimated exposures for 61 job categories ranged from 0.03 to 0.68 microT; the 25th, 50th, and 75th percentiles were 0.135, 0.17, and 0.23 microT, respectively. By job category, the most highly exposed jobs (>0.23 microT) included bakery worker, cashier, cook and kitchen worker, electronics worker, residential and industrial sewing machine operator, and textile machine operator. By work environment, the most highly exposed job categories were electronics worker in an assembly plant (0.70 microT) and sewing machine operators in a textile factory (0.68 microT) and shoe factory (0.66 microT). These results provide new information on expected levels of exposure in a wide range of jobs commonly held by women. PMID:11836202

  10. Forest-Water Feedbacks Under a Changing Climate

    NASA Astrophysics Data System (ADS)

    Creed, I. F.; Hwang, T.

    2015-12-01

    Among the most valuable products produced by forests are the ecosystem services of safe and reliable water supplies. The provision of these ecosystem services on forested landscapes is inherently linked to forest condition. Climate change and associated hydrological intensification may affect forest water use (green water) and runoff generation (blue water) in the temperate forest biome of eastern North America. For the time period from the 1980s to present, a period with significant climate warming, we used a network of long-term catchment study sites nested within the temperate forest biome to explore forest-water feedbacks in response to climate change. Satellite remote sensing was used to track changes in forest phenology and forest productivity, and catchment meteorological and discharge records were used to track changes in the magnitude and timing of forest water yields. Forest responses to climate change varied along a latitudinal gradient. The magnitude of annual water yields declined at all study sites. The timing of peak discharge was measured by the center of mass (i.e., 50th percentile), and the narrowing or widening of discharge periods was measured by the coefficient of dispersion (i.e., 75th - 25th over 50th percentile) of water yield. For the vernal window, we observed subtle and systematic changes with a shift to later peaks in the center of mass of spring discharge and a widening of the spring discharge period (i.e., less peaked flows). For the autumnal window, we observed less subtle, non-systematic changes with a shift to later peaks above 45 degrees latitude but earlier peaks below 45 degrees latitude, and a narrowing of the fall discharge period (i.e., more peaked flows). The time shift and widening of vernal and autumnal windows are likely caused by asymmetric responses of forest water use (green water) and runoff generation (blue water) to climate warming. These disruptions in forest-water coupling are likely to have significant

  11. The 50th Anniversary of the Cahn-Ingold-Prelog Specification of Molecular Chirality.

    PubMed

    Helmchen, Günter

    2016-06-01

    "… Just over 50 years ago, Robert S. Cahn, Sir Christopher Ingold, and Vladimir Prelog published the Review 'Specification of Molecular Chirality' in Angewandte Chemie. The article would change the everyday language of the chemist by bringing the term chirality to their attention. Today, the CIP system is the specification tool in organic chemistry …" Read more in the Editorial by Günter Helmchen. PMID:27151758

  12. The 50th ASMS Conference on Mass Spectrometry and Allied Topics

    PubMed Central

    2002-01-01

    Development of new mass spectrometers and implementation of new analytical methods were the central themes of the conference. The majority of oral presentations and posters were concerned with the application of mass spectrometry to pharmaceutical and biotechnological research. PMID:18629048

  13. A resolution commemorating the 50th Anniversary of the Cape May-Lewes Ferry.

    THOMAS, 113th Congress

    Sen. Coons, Christopher A. [D-DE

    2014-06-26

    06/26/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S4190; text as passed Senate: CR S4165) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  14. A resolution commemorating the 50th anniversary of the Wilderness Act.

    THOMAS, 113th Congress

    Sen. Wyden, Ron [D-OR

    2014-09-18

    09/18/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S5880; text as passed Senate: CR S5799-5800) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  15. 'Focus on Marshall' Features Marshall’s 50th Anniversary

    NASA Video Gallery

    On March 15, 1960, President Dwight Eisenhower issued an executive order designating NASA's first field center as the George C. Marshall Space Flight Center. On the November episode of “Focus on ...

  16. 76 FR 72821 - 50th Anniversary of the United States Agency for International Development

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... States of America the two hundred and thirty- sixth. (Presidential Sig.) [FR Doc. 2011-30722 Filed 11-25... 1961, the men and women of USAID have worked on the front lines of poverty and conflict to support... against hunger, poverty, and disease. As USAID continues to shape a brighter future for generations...

  17. 75 FR 76611 - 50th Anniversary of the Arctic National Wildlife Refuge

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-09

    ... of the United States of America the two hundred and thirty-fifth. (Presidential Sig.) [FR Doc. 2010... Wildlife Refuge, I encourage all Americans to recognize the beauty and diversity of all of America's...

  18. The 50th Anniversary of the Thayer Conference: Historical Perspectives and Accomplishments

    ERIC Educational Resources Information Center

    Fagan, Thomas K.

    2005-01-01

    Information from several historical sources provides a clearer understanding of the Thayer Conference, including little-known background information. Changes in school psychology since the conference are described through comparisons of the field at the time of the conference and at present. Major recommendations and expectations emanating from…

  19. A resolution celebrating the 50th anniversary of the 1962 Seattle World's Fair.

    THOMAS, 112th Congress

    Sen. Cantwell, Maria [D-WA

    2012-04-19

    04/19/2012 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S2553-2554) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  20. "The upper limits of vegetation on Mauna Loa, Hawaii": a 50th-anniversary reassessment.

    PubMed

    Juvik, James O; Rodomsky, Brett T; Price, Jonathan P; Hansen, Eric W; Kueffer, Christoph

    2011-02-01

    In January 1958, a survey of alpine flora was conducted along a recently constructed access road across the upper volcanic slopes of Mauna Loa, Hawaii (2525-3397 m). Only five native Hawaiian species were encountered on sparsely vegetated historic and prehistoric lava flows adjacent to the roadway. A resurvey of roadside flora in 2008 yielded a more than fourfold increase to 22 species, including nine native species not previously recorded. Eight new alien species have now invaded this alpine environment, although exclusively limited to a few individuals in ruderal habitat along the roadway. Alternative explanations for species invasion and altitudinal change over the past 50 years are evaluated: (1) changes related to continuing primary succession on ameliorating (weathering) young lava substrates; (2) local climate change; and (3) road improvements and increased vehicular access which promote enhanced car-borne dispersal of alien species derived from the expanding pool of potential colonizers naturalized on the island in recent decades. Unlike alpine environments in temperate latitudes, the energy component (warming) in climate change on Mauna Loa does not appear to be the unequivocal driver of plant invasion and range extension. Warming may be offset by other climate change factors including rainfall and evapotranspiration. PMID:21618930

  1. Physical Modeling of Landslide Generated Tsunamis and the 50th Anniversary of the Vajont Dam Disaster

    NASA Astrophysics Data System (ADS)

    McFall, Brian C.; Mohammed, Fahad; Fritz, Hermann M.

    2013-04-01

    The Vajont river is an affluent of the Piave River located in the Dolomite Alps of the Veneto Region, about 100km north of Venice. A 265.5 m high double curved arch dam was built across a V-shaped gorge creating a reservoir with a maximum storage capacity of 0.169 km3. A maximum water depth of 250 m was reached by early September 1963 during the third filling attempt of the reservoir, but as creeping on the southern flank increased the third reservoir draw down was initiated. By October 9, 1963 the water depth was lowered to 240m as the southern flank of Vajont reservoir catastrophically collapsed on a length of more than 2km. Collapse occurred during reservoir drawdown in a final attempt to reduce flank creeping and the reservoir was only about two-thirds full. The partially submerged rockslide with a volume of 0.24 km3 penetrated into the reservoir at velocities up to 30 m/s. The wave runup in direct prolongation of slide axis reached the lowest houses of Casso 270m above reservoir level before impact corresponding to 245m above dam crest (Müller, 1964). The rockslide deposit came within 50m of the left abutment and towers up to 140m above the dam crest. The lateral spreading of the surge overtopped the dam crest by more than 100m. The thin arch dam withstood the overtopping and sustained no damage to the structural shell and the abutments. The flood wave dropped more than 500m down the Vajont gorge and into the Piave Valley causing utter destruction to the villages of Longarone, Pirago, Villanova, Rivalta and Fae. More than 2000 persons perished. The Vajont disaster highlights an extreme landslide tsunami event in the narrowly confined water body of a reservoir. Landslide tsunami hazards exist even in areas not exposed to tectonic tsunamis. Source and runup scenarios based on real world events are physically modeled in the three dimensional NEES tsunami wave basin (TWB) at Oregon State University (OSU). A novel pneumatic landslide tsunami generator (LTG) was deployed to simulate landslides with varying geometry and kinematics. The LTG consists of a sliding box filled with up to 1,350 kg of naturally rounded river gravel which is accelerated by means of four pneumatic pistons down the 2H: 1V slope, launching the granular landslide towards the water at velocities of up to 5 m/s. Topographical and bathymetric features can greatly affect wave characteristics and runup heights. Landslide tsunamis are studied in different topographic and bathymetric configurations: far field propagation and runup, a narrow fjord and curved headland configurations, and a conical island setting representing landslides off an island or a volcanic flank collapse. Water surface elevations were measured using an array of resistance wave gauges. The granulate landslide shape and front velocity were measured using above and underwater cameras. Three-dimensional landslide surfaces with surface velocities were reconstruction using a stereo particle image velocimetry (PIV) setup. The speckled pattern on the surface of the granular landslide allows for cross-correlation based PIV analysis. Wave runup was measured with resistance wave gauges along the slope and verified with video image processing. The measured landslide and tsunami data serve to validate and advance 3-dimensional numerical landslide tsunami and prediction models.

  2. 77 FR 32873 - Commemoration of the 50th Anniversary of the Vietnam War

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... hundred and thirty-sixth. (Presidential Sig.) [FR Doc. 2012-13514 Filed 5-31-12; 11:15 am] Billing code... home. In the reflection of The Wall, we see the military family members and veterans who carry a...

  3. 77 FR 63203 - 50th Anniversary of the Office of the United States Trade Representative

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... United States Trade Representative (USTR) continues to play a vital role in advancing trade policy that... the United States of America the two hundred and thirty-seventh. (Presidential Sig.) [FR Doc. 2012... Trade Representative By the President of the United States of America A Proclamation On October 11,...

  4. A resolution recognizing the Defense Intelligence Agency on its 50th Anniversary.

    THOMAS, 112th Congress

    Sen. Feinstein, Dianne [D-CA

    2011-03-01

    05/12/2011 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S2970) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  5. The Save-WEFM Case as Reported to the 50th Annual NAEB Convention, 1974.

    ERIC Educational Resources Information Center

    Danna, Sammy R.

    The history of Chicago FM radio station WEFM and the activities of the Citizen's Committee to Save WEFM are chronicled. The focus is principally on the actions of the Citizen's Committee to prevent the conversion of the radio station from a classical music format to rock and roll offerings and to block the sale of the station by Zenith to GCC…

  6. A resolution commemorating the 50th anniversary of the Combined Federal Campaign.

    THOMAS, 112th Congress

    Sen. Akaka, Daniel K. [D-HI

    2011-10-18

    11/16/2011 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (consideration: CR S7627; text as passed Senate: CR S7627) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  7. [The cradle of the Russian radioecology (to the 50th anniversary of the Kyshtym radiation accident)].

    PubMed

    Aleksakhin, R M; Prister, B S

    2008-01-01

    On September 29, 1957, at a nuclear industry facility (Production Association "Mayak"), there was a large radiation accident resulting in the release of radioactive wastes into the environment and the formation of the East-Urals Radioactive Trail (EURT). Within the EURT and there established in 1958 an Experimental Scientific Research Station (ESRS) which came to be known as alma mater of domestic radioecology, various comprehensive long-term investigations had been carried out. The main results of these 50-year investigations have been summarized for a broad range of problems on radionuclide migration in the natural environment and ionizing radiation effects on biota, as well as problems of environmental protection. In addition to the studies of the in situ behavior of released during the accident anthropogenic radionuclides (primarily 90Sr, the main dose-forming radionuclide within the EURT), at the ESRS large experiment have been performed to study migration and biological effects on agricultural plants and animals of man-made radionuclides (especially fresh mixtures of fission products) introduced to the natural environment. Results of ESRS experiments are described on irradiation of natural biogeocenoses from a powerful source of ionizing radiation (1.2 x 10(15) Bq 137Cs). The first unique experience is described of remediation of radioactively contaminated areas with emphasis on agricultural radioecology. The importance of the EURT and ESRS radioecological studies for the development of radioecology as a science is stressed. PMID:18666658

  8. A resolution commemorating the 50th anniversary of the publication of "To Kill a Mockingbird".

    THOMAS, 111th Congress

    Sen. Sessions, Jeff [R-AL

    2010-08-05

    08/05/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6981; text as passed Senate: CR S6981; text of measure as introduced: CR S6908) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  9. Succeed or Else!: Reflections on the 50th Anniversary of the "Journal of Educational Administration"

    ERIC Educational Resources Information Center

    Thomas, A. Ross

    2012-01-01

    Purpose: The purpose of this paper is to identify the key individuals, associations and significant events contributing to the establishment and first 50 years of successful publication of the "Journal of Educational Administration". Design/methodology/approach: This paper is historical in design. Information relevant to its 50 years of…

  10. The 50th Anniversary of "Brown": Is There Any Reason to Celebrate?

    ERIC Educational Resources Information Center

    Eckes, Suzanne E.

    2004-01-01

    The "Brown v. Board of Education" decision remains one of the most important legal decisions in history. Although there were local schemes used to avoid desegregating public schools after the decision, black students experienced declining segregation from the 1950s to the late 1980s. During the 1990s, however, a series of Supreme Court decisions…

  11. Celebrating the 50th anniversary of the American Academy of Psychoanalysis and Dynamic Psychiatry.

    PubMed

    Eckardt, Marianne Horney

    2006-01-01

    On the occasion of its 50 anniversary, the members of the American Academy of Psychoanalysis and Dynamic Psychiatry can look back with pride and be aware that this professional society has been true to its original goal and passionate mission. Thanks for this momentous accomplishment goes to its founding fathers and mothers, who were clear in their purpose and whose wisdom is manifest in the Academy's constitution. In the 1930s, the orthodoxy of the American Psychoanalytic Association created a ferment of rebellion in most of its institutes, which led to secessions, sister institutes, and a greater open-mindedness in institutes residing in Chicago, Washington, New Orleans, and Detroit. The quest for a new national forum that would be open to an exchange of new ideas began in 1951 and culminated in the formation of the American Academy of Psychoanalysis in 1956. The spirit of the Academy is highlighted by relating the successful struggle of communication among its members in a dream workshop that existed for six years. PMID:16548742

  12. Characterization of selected biological, chemical, and physical conditions at fixed sites in the Upper Colorado River basin, Colorado, 1995-98

    USGS Publications Warehouse

    Deacon, Jeffrey R.; Mize, Scott V.; Spahr, Norman E.

    1999-01-01

    at mining land-use sites than at the background site and were less than the 50th percentile of those for sites from the three other NAWQA study units. Nutrient concentrations at urban and recreation sites in the Southern Rocky Mountain physiographic province generally were greater than concentrations at the background site and generally were between the 25th and 90th percentile of concentrations for sites from the three other NAWQA study units. Habitat conditions and fish communities at urban and recreation sites were slightly degraded compared to the background site. EPT richness and the percentage of EPT were lower at urban and recreation sites than at the background site and were between the 25th and 75th percentile of those for sites from the three other NAWQA study units. The percentage of Chironomidae, which may be indicative of pollutant-tolerant organisms, was higher at urban and recreation sites than at the background site. Mixed land-use sites in the Southern Rocky Mountains physiographic province had similar nutrient concentrations and similar cadmium and zinc streambed-sediment concentrations. Fish-community degradation index values were very different among the three mixed land-use sites in the Southern Rocky Mountains physiographic province. Larger percentages of omnivores and anomalies such as lesions and deformities at two mixed land-use sites resulted in higher degradation values of the fish community. Agriculture land-use sites had higher concentrations of nutrients and selenium than the background site in the Colorado Plateau physiographic province. Concentrations of p,p'-DDE in fish tissue at agriculture sites were higher than the 75th percentile of concentrations for sites from the three other NAWQA study units. Fish communities had degradation values near the 75th percentile for agriculture sites. The percentage of EPT was low at agriculture sites when compared to the background site. Two mixed land-use sites in the Colorado Plateau physiographi

  13. Estimated water use and availability in the lower Blackstone River basin, northern Rhode Island and south-central Massachusetts, 1995-99

    USGS Publications Warehouse

    Barolw, Lora K.

    2003-01-01

    flow, an estimated median rate of 50.5 Mgal/d of water was available for the basin during August, the lowest base-flow month. In addition, basin-wide water-availability estimates were calculated with and without streamflow criteria for each month of the low-flow period at the 75th, 50th, and 25th percentiles of base flow. These water availability estimates ranged from 42.3 to 181.7 Mgal/d in June; 20.2 to 96.7 Mgal/d in July; 20.2 to 85.4 Mgal/d in August, and 20.2 to 97.5 Mgal/d in September. Base flow was less than the Aquatic Base Flow (ABF), minimum flow considered adequate to protect aquatic fauna, from July through September at the 25th percentile and in August and September at the 50th percentile. A basin-stress ratio, which is equal to total withdrawals divided by water availability, was also calculated. The basin-stress ratio for August at the 50th percentile of base flow minus the 7Q10 was 0.68 for the study area. For individual subbasins, the ratio ranged from 0.13 in the Chepachet River subbasin to 0.95 in the Abbot Run subbasin. In addition, basin-stress ratios with and without streamflow criteria for all four months of the low-flow period were calculated at the 75th, 50th, and 25th percentiles of base flow. These values ranged from 0.19 to 0.83 in June, 0.36 to 1.50 in July, 0.40 to 1.14 in August, and 0.31 to 0.78 in September. Ratios could not be calculated by using the ABF at the 50th and 25th percentiles in August and September because the estimated base flow was less than the ABF. The depletion of the Blackstone River flows by Cumberland Water Department Manville well no. 1 in Rhode Island was estimated with the computer program STRMDEPL and specified daily pumping rates. STRMDEPL uses analytical solutions to calculate time-varying rates of streamflow depletion caused by pumping at wells. Results show that streamflow depletions were about 97 percent of average daily pumping rates for 1995 through 1999. Relative streamflow depletions for

  14. Distributions of median nutrient and chlorophyll concentrations across the Red River Basin, USA.

    PubMed

    Longing, D; Haggard, B E

    2010-01-01

    Acquisition and compilation of water-quality data for an 11-yr time period (1996-2006) from 589 stream and river stations were conducted to support nutrient criteria development for the multistate Red River Basin shared by Arkansas, Louisiana, New Mexico, Oklahoma, and Texas. Ten water-quality parameters were collected from six data sources (USGS, Arkansas Department of Environmental Quality, Louisiana Department of Environmental Quality, Oklahoma Conservation Commission, Oklahoma Water Resources Board, and Texas Commission on Environmental Quality), and an additional 13 parameters were acquired from at least one source. Median concentrations of water-quality parameters were calculated at each individual station and frequency distributions (minimum, 10th, 25th, 50th, 75th, 90th percentiles, and maximum) of the median concentrations were calculated. Across the Red River Basin, median values for total nitrogen (TN), total phosphorus (TP), and sestonic chlorophyll-a (chl-a) ranged from < 0.02 to 20.2 mg L(-1), < 0.01 to 6.66 mg L(-1), and 0.10 to 262 microg L(-1), respectively. Overall, the 25th percentiles of TN data specific to the Red River Basin were generally similar to the USEPA-recommended ecoregion nutrient criteria of 0.31 to 0.88 mg L(-1), whereas median TP and chl-a data specific to the Red River Basin showed 25th percentiles higher than the USEPA-recommended criteria (0.010-0.067 mg TP L(-1); 0.93-3.00 microg chl-a L(-1)). The unique location of the Red River Basin in the south-central United States places it near the boundaries of several aggregate ecoregions; therefore, the development of ecoregion nutrient criteria likely requires using data specific to the Red River Basin, as shown in these analyses. This study provided basin-specific frequency distribution of median concentrations of water-quality parameters as the first step to support states in developing nutrient criteria to protect designated uses in the multijurisdictional Red River Basin. PMID

  15. Effectiveness of Intelligent Tutoring Systems: A Meta-Analytic Review

    ERIC Educational Resources Information Center

    Kulik, James A.; Fletcher, J. D.

    2016-01-01

    This review describes a meta-analysis of findings from 50 controlled evaluations of intelligent computer tutoring systems. The median effect of intelligent tutoring in the 50 evaluations was to raise test scores 0.66 standard deviations over conventional levels, or from the 50th to the 75th percentile. However, the amount of improvement found in…

  16. BRENDA in 2015: exciting developments in its 25th year of existence

    PubMed Central

    Chang, Antje; Schomburg, Ida; Placzek, Sandra; Jeske, Lisa; Ulbrich, Marcus; Xiao, Mei; Sensen, Christoph W.; Schomburg, Dietmar

    2015-01-01

    The BRENDA enzyme information system (http://www.brenda-enzymes.org/) has developed into an elaborate system of enzyme and enzyme-ligand information obtained from different sources, combined with flexible query systems and evaluation tools. The information is obtained by manual extraction from primary literature, text and data mining, data integration, and prediction algorithms. Approximately 300 million data include enzyme function and molecular data from more than 30 000 organisms. The manually derived core contains 3 million data from 77 000 enzymes annotated from 135 000 literature references. Each entry is connected to the literature reference and the source organism. They are complemented by information on occurrence, enzyme/disease relationships from text mining, sequences and 3D structures from other databases, and predicted enzyme location and genome annotation. Functional and structural data of more than 190 000 enzyme ligands are stored in BRENDA. New features improving the functionality and analysis tools were implemented. The human anatomy atlas CAVEman is linked to the BRENDA Tissue Ontology terms providing a connection between anatomical and functional enzyme data. Word Maps for enzymes obtained from PubMed abstracts highlight application and scientific relevance of enzymes. The EnzymeDetector genome annotation tool and the reaction database BKM-react including reactions from BRENDA, KEGG and MetaCyc were improved. The website was redesigned providing new query options. PMID:25378310

  17. Coseismic landsliding associated with the 2015 April 25th Gorkha earthquake, Nepal

    NASA Astrophysics Data System (ADS)

    Clark, Marin; Zekkos, Dimitrios; West, A. Joshua; Gallen, Sean; Roback, Kevin; Chamlagain, Deepak; Athanasopoulos-Zekkos, Adda; Greenwood, William; Bateman, Julie; Partenio, Michael; Li, Gen; Cook, Kristen; Godt, Jonathan; Howat, Ian; Morin, Paul

    2016-04-01

    The characteristics of earthquake-triggered landslides have the potential to inform us about the ground motions during large earthquakes and the rock properties of the near surface environment. From the recent Mw7.8 2015 Gorkha earthquake in Nepal, we use satellite imagery to identify over 20,000 landslides that are associated with the main shock. While most landslides are located on steep hillslopes, we also present field measurements of alluvial terraces that have either failed or remained stable during the earthquake. We show how both hillslope and terrace failures can be used to better understand the earthquake. These local, site-specific surveys and analyses of alluvial terraces can be used to constrain co-seismic peak ground acceleration (PGA) and large landslide inventories can be used to gain insight into regional patterns of strong ground motion. Our regional landslide mapping reveals two principal patterns: (1) landslides are concentrated in the steep Greater Himalaya in the north, with conspicuously fewer landslides in the moderately-steep Lesser Himalaya in the south, and (2) within the Greater Himalaya, landslide density increases from west to east across the rupture area. We have compared our observed map of landslide occurrence to predictions from forward models using hillslope angles, average rock strength, and PGA estimated from ground motion prediction equations (GMPE). The higher concentration of landslides in the Greater Himalaya compared to the Lesser Himalaya can be predicted by the models and explained by the steeper topography of the Greater Himalaya. However, these forward models do not reproduce the east to west variation in observed landslide density, which is lower than model predictions near the epicenter, and greater than model predictions toward the eastern limit of the rupture. From limit equilibrium stability analysis of both failed and stable fluvial terraces, we constrain local PGA values in the eastern region of dense landsliding. We estimate higher PGA values than those predicted based on GMPE, which could in part explain the concentration of hillslope landsliding. An additional effect that may explain higher landslide density may be the concentration of high-frequency seismic energy, which is observed from high-rate GPS and teleseismic back-projections, since high-frequency spectra promote slope failure. Spatial variability in rock strength could also influence regional landslide distributions; this factor will be investigated with future shallow seismic and field observations. If the observed rupture characteristics of the Gorkha earthquake are typical of large earthquakes in the Himalaya, concentrated landsliding could locally deliver coarse sediment to river channels. Over the long term, spatially focused delivery of coarse sediment may lead to steepened river gradients and higher erosion rates that vary along strike of the Himalaya, provided that coseismic sediment production is mobilized and transported efficiently during the interseismic period. Ongoing work includes evaluating river sediment grain size. If a spatial correlation between coseismic landsliding, increased sediment grain size, and elevated erosion rates can be shown, it would demonstrate a new example of tectonic-erosion coupling based on the seismic cycle and fault behavior.

  18. 25th Anniversary Article: A Soft Future: From Robots and Sensor Skin to Energy Harvesters

    PubMed Central

    Bauer, Siegfried; Bauer-Gogonea, Simona; Graz, Ingrid; Kaltenbrunner, Martin; Keplinger, Christoph; Schwödiauer, Reinhard

    2014-01-01

    Scientists are exploring elastic and soft forms of robots, electronic skin and energy harvesters, dreaming to mimic nature and to enable novel applications in wide fields, from consumer and mobile appliances to biomedical systems, sports and healthcare. All conceivable classes of materials with a wide range of mechanical, physical and chemical properties are employed, from liquids and gels to organic and inorganic solids. Functionalities never seen before are achieved. In this review we discuss soft robots which allow actuation with several degrees of freedom. We show that different actuation mechanisms lead to similar actuators, capable of complex and smooth movements in 3d space. We introduce latest research examples in sensor skin development and discuss ultraflexible electronic circuits, light emitting diodes and solar cells as examples. Additional functionalities of sensor skin, such as visual sensors inspired by animal eyes, camouflage, self-cleaning and healing and on-skin energy storage and generation are briefly reviewed. Finally, we discuss a paradigm change in energy harvesting, away from hard energy generators to soft ones based on dielectric elastomers. Such systems are shown to work with high energy of conversion, making them potentially interesting for harvesting mechanical energy from human gait, winds and ocean waves. PMID:24307641

  19. 25th anniversary article: A soft future: from robots and sensor skin to energy harvesters.

    PubMed

    Bauer, Siegfried; Bauer-Gogonea, Simona; Graz, Ingrid; Kaltenbrunner, Martin; Keplinger, Christoph; Schwödiauer, Reinhard

    2014-01-01

    Scientists are exploring elastic and soft forms of robots, electronic skin and energy harvesters, dreaming to mimic nature and to enable novel applications in wide fields, from consumer and mobile appliances to biomedical systems, sports and healthcare. All conceivable classes of materials with a wide range of mechanical, physical and chemical properties are employed, from liquids and gels to organic and inorganic solids. Functionalities never seen before are achieved. In this review we discuss soft robots which allow actuation with several degrees of freedom. We show that different actuation mechanisms lead to similar actuators, capable of complex and smooth movements in 3d space. We introduce latest research examples in sensor skin development and discuss ultraflexible electronic circuits, light emitting diodes and solar cells as examples. Additional functionalities of sensor skin, such as visual sensors inspired by animal eyes, camouflage, self-cleaning and healing and on-skin energy storage and generation are briefly reviewed. Finally, we discuss a paradigm change in energy harvesting, away from hard energy generators to soft ones based on dielectric elastomers. Such systems are shown to work with high energy of conversion, making them potentially interesting for harvesting mechanical energy from human gait, winds and ocean waves. PMID:24307641

  20. 25th RCOphth Congress, President's Session paper: 25 years of progress in medical retina

    PubMed Central

    Gibson, J M

    2014-01-01

    The quarter century since the foundation of the Royal College of Ophthalmologists has coincided with immense change in the subspecialty of medical retina, which has moved from being the province of a few dedicated enthusiasts to being an integral, core part of ophthalmology in every eye department. In age-related macular degeneration, there has been a move away from targeted, destructive laser therapy, dependent on fluorescein angiography to intravitreal injection therapy of anti-growth factor agents, largely guided by optical coherence tomography. As a result of these changes, ophthalmologists have witnessed a marked improvement in visual outcomes for their patients with wet age-related macular degeneration (AMD), while at the same time developing and enacting entirely novel ways of delivering care. In the field of diabetic retinopathy, this period also saw advances in laser technology and a move away from highly destructive laser photocoagulation treatment to gentler retinal laser treatments. The introduction of intravitreal therapies, both steroids and anti-growth factor agents, has further advanced the treatment of diabetic macular oedema. This era has also seen in the United Kingdom the introduction of a coordinated national diabetic retinopathy screening programme, which offers an increasing hope that the burden of blindness from diabetic eye disease can be lessened. Exciting future advances in retinal imaging, genetics, and pharmacology will allow us to further improve outcomes for our patients and for ophthalmologists specialising in medical retina, the future looks very exciting but increasingly busy. PMID:24993325

  1. Attitudes and Opinions from the Nation's High Achieving Teens. 25th Annual Survey of High Achievers.

    ERIC Educational Resources Information Center

    Who's Who among American High School Students, Lake Forest, IL.

    This survey was conducted during the spring of 1994 for the purpose of determining the attitudes of student leaders in the nation's high schools. Eight thousand surveys were sent out to students, of which 3177 were returned. All students surveyed were members of the junior or senior class during the 1993-94 academic year. They were selected for…

  2. 25th anniversary article: Rise to power--OPV-based solar parks.

    PubMed

    Krebs, Frederik C; Espinosa, Nieves; Hösel, Markus; Søndergaard, Roar R; Jørgensen, Mikkel

    2014-01-01

    A solar park based on polymer solar cells is described and analyzed with respect to performance, practicality, installation speed, and energy payback time. It is found that a high voltage installation where solar cells are all printed in series enables an installation rate in Watts installed per minute that far exceed any other PV technology in existence. The energy payback time for the practical installation of polymer solar cell foil on a wooden 250 square meter platform in its present form is 277 days when operated in Denmark and 180 days when operated in southern Spain. The installation and de-installation rate is above 100 m min⁻¹, which, with the present performance and web width, implies installation of >200 W min⁻¹. In comparison, this also exceeds the overall manufacturing speed of the polymer solar cell foil with a width of 305 mm which is currently 1 m min⁻¹ for complete encapsulated and tested foil. It is also significant that simultaneous installation and de-installation which enables efficient schemes for decommissioning and recycling is possible. It is highlighted where research efforts should most rationally be invested in order to make grid electricity from OPV a reality (and it is within reach). PMID:24741693

  3. 25th Space Simulation Conference. Environmental Testing: The Earth-Space Connection

    NASA Technical Reports Server (NTRS)

    Packard, Edward

    2008-01-01

    Topics covered include: Methods of Helium Injection and Removal for Heat Transfer Augmentation; The ESA Large Space Simulator Mechanical Ground Support Equipment for Spacecraft Testing; Temperature Stability and Control Requirements for Thermal Vacuum/Thermal Balance Testing of the Aquarius Radiometer; The Liquid Nitrogen System for Chamber A: A Change from Original Forced Flow Design to a Natural Flow (Thermo Siphon) System; Return to Mercury: A Comparison of Solar Simulation and Flight Data for the MESSENGER Spacecraft; Floating Pressure Conversion and Equipment Upgrades of Two 3.5kw, 20k, Helium Refrigerators; Affect of Air Leakage into a Thermal-Vacuum Chamber on Helium Refrigeration Heat Load; Special ISO Class 6 Cleanroom for the Lunar Reconnaissance Orbiter (LRO) Project; A State-of-the-Art Contamination Effects Research and Test Facility Martian Dust Simulator; Cleanroom Design Practices and Their Influence on Particle Counts; Extra Terrestrial Environmental Chamber Design; Contamination Sources Effects Analysis (CSEA) - A Tool to Balance Cost/Schedule While Managing Facility Availability; SES and Acoustics at GSFC; HST Super Lightweight Interchangeable Carrier (SLIC) Static Test; Virtual Shaker Testing: Simulation Technology Improves Vibration Test Performance; Estimating Shock Spectra: Extensions beyond GEVS; Structural Dynamic Analysis of a Spacecraft Multi-DOF Shaker Table; Direct Field Acoustic Testing; Manufacture of Cryoshroud Surfaces for Space Simulation Chambers; The New LOTIS Test Facility; Thermal Vacuum Control Systems Options for Test Facilities; Extremely High Vacuum Chamber for Low Outgassing Processing at NASA Goddard; Precision Cleaning - Path to Premier; The New Anechoic Shielded Chambers Designed for Space and Commercial Applications at LIT; Extraction of Thermal Performance Values from Samples in the Lunar Dust Adhesion Bell Jar; Thermal (Silicon Diode) Data Acquisition System; Aquarius's Instrument Science Data System (ISDS) Automated to Acquire, Process, Trend Data and Produce Radiometric System Assessment Reports; Exhaustive Thresholds and Resistance Checkpoints; Reconfigurable HIL Testing of Earth Satellites; FPGA Control System for the Automated Test of MicroShutters; Ongoing Capabilities and Developments of Re-Entry Plasma Ground Tests at EADS-ASTRIUM; Operationally Responsive Space Standard Bus Battery Thermal Balance Testing and Heat Dissipation Analysis; Galileo - The Serial-Production AIT Challenge; The Space Systems Environmental Test Facility Database (SSETFD), Website Development Status; Simulated Reentry Heating by Torching; Micro-Vibration Measurements on Thermally Loaded Multi-Layer Insulation Samples in Vacuum; High Temperature Life Testing of 80Ni-20Cr Wire in a Simulated Mars Atmosphere for the Sample Analysis at Mars (SAM) Instrument Suit Gas Processing System (GPS) Carbon Dioxide Scrubber; The Planning and Implementation of Test Facility Improvements; and Development of a Silicon Carbide Molecular Beam Nozzle for Simulation Planetary Flybys and Low-Earth Orbit.

  4. The 25th Annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting

    NASA Technical Reports Server (NTRS)

    Sydnor, Richard L. (Editor)

    1994-01-01

    Papers in the following categories are presented: recent developments in rubidium, cesium, and hydrogen-based frequency standards, and in cryogenic and trapped-ion technology; international and transnational applications of precise time and time interval (PTTI) technology with emphasis on satellite laser tracking networks, GLONASS timing, intercomparison of national time scales and international telecommunication; applications of PTTI technology to the telecommunications, power distribution, platform positioning, and geophysical survey industries; application of PTTI technology to evolving military communications and navigation systems; and dissemination of precise time and frequency by means of GPS, GLONASS, MILSTAR, LORAN, and synchronous communications satellites.

  5. 25th RCOphth Congress, President's Session paper: 25 years of progress in vitreoretinal surgery

    PubMed Central

    Aylward, G W

    2014-01-01

    Over the past 25 years, vitreoretinal surgery has undergone considerable change in technology, techniques, and professional organisation. Many conditions that were considered untreatable in 1988 are now treated routinely by vitreoretinal surgeons. Over the same period, vitreoretinal surgery has become a separate subspecialty with its own scientific meetings and professional organisation. This article describes a noncomprehensive selection of some of the highlights of the past 25 years, including the establishment and growth of BEAVRS (British and Eire Association of Vitreoretinal Surgeons), the revolution in the management of macular holes, the development of submacular surgery, and the introduction of sutureless vitrectomy. PMID:24993322

  6. 25th anniversary article: label-free electrical biodetection using carbon nanostructures.

    PubMed

    Balasubramanian, Kannan; Kern, Klaus

    2014-02-26

    Nanostructures are promising candidates for use as active materials for the detection of chemical and biological species, mainly due to the high surface-to-volume ratio and the unique physical properties arising at the nanoscale. Among the various nanostructures, materials comprised of sp(2) -carbon enjoy a unique position due to the possibility to readily prepare them in various dimensions ranging from 0D, through 1D to 2D. This review focuses on the use of 1D (carbon nanotubes) and 2D (graphene) carbon nanostructures for the detection of biologically relevant molecules. A key advantage is the possibility to perform the sensing operation without the use of any labels or complex reaction schemes. Along this spirit, various strategies reported for the label-free electrical detection of biomolecules using carbon nanostructures are discussed. With their promise for ultimate sensitivity and the capability to attain high selectivity through controlled chemical functionalization, carbon-based nanobiosensors are expected to open avenues to novel diagnostic tools as well as to obtain new fundamental insight into biomolecular interactions down to the single molecule level. PMID:24452968

  7. A resolution recognizing the 25th anniversary of the Chernobyl nuclear disaster.

    THOMAS, 112th Congress

    Sen. Lugar, Richard G. [R-IN

    2011-04-14

    05/09/2011 Resolution agreed to in Senate with an amendment and with a preamble by Unanimous Consent. (text: CR S2799) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  8. 25th anniversary article: semiconductor nanowires--synthesis, characterization, and applications.

    PubMed

    Dasgupta, Neil P; Sun, Jianwei; Liu, Chong; Brittman, Sarah; Andrews, Sean C; Lim, Jongwoo; Gao, Hanwei; Yan, Ruoxue; Yang, Peidong

    2014-04-01

    Semiconductor nanowires (NWs) have been studied extensively for over two decades for their novel electronic, photonic, thermal, electrochemical and mechanical properties. This comprehensive review article summarizes major advances in the synthesis, characterization, and application of these materials in the past decade. Developments in the understanding of the fundamental principles of "bottom-up" growth mechanisms are presented, with an emphasis on rational control of the morphology, stoichiometry, and crystal structure of the materials. This is followed by a discussion of the application of nanowires in i) electronic, ii) sensor, iii) photonic, iv) thermoelectric, v) photovoltaic, vi) photoelectrochemical, vii) battery, viii) mechanical, and ix) biological applications. Throughout the discussion, a detailed explanation of the unique properties associated with the one-dimensional nanowire geometry will be presented, and the benefits of these properties for the various applications will be highlighted. The review concludes with a brief perspective on future research directions, and remaining barriers which must be overcome for the successful commercial application of these technologies. PMID:24604701

  9. Unexpected earthquake of June 25th, 2015 in Madiun, East Java

    NASA Astrophysics Data System (ADS)

    Nugraha, Andri Dian; Supendi, Pepen; Shiddiqi, Hasbi Ash; Widiyantoro, Sri

    2016-05-01

    An earthquake with magnitude 4.2 struck Madiun and its vicinity on June 25, 2015. According to Indonesian Meteorology, Climatology, and Geophysics Agency (BMKG), the earthquake occurred at 10:35:29 GMT+7 and was located in 7.73° S, 111.69 ° E, with a depth of 10 km. At least 57 houses suffered from light to medium damages. We reprocessed earthquake waveform data to obtain an accurate hypocenter location. We manually picked P- and S-waves arrival times from 12 seismic stations in the eastern part of Java. Earthquake location was determined by using Hypoellipse code that employs a single event determination method. Our inversion is able to resolve the fix-depth and shows that the earthquake occurred at 10:35:27.6 GMT+7 and was located in 7.6305° S, 111.7529 ° E with 14.81 km focus depth. Our location depicts a smaller travel time residual compared to that based on the BMKG result. Focal mechanism of the earthquake was determined by using HASH code. We used first arrival polarity of 9 seismic records with azimuthal gap less than 90°, and estimated take-off angles by using assumption of homogenous medium. Our focal mechanism solution shows a strike-slip mechanism with strike direction of 163o, which may be related to a strike-fault in Klangon, an area to the east of Madiun.

  10. Development and External Debt: Friend or Foe? Academy for Educational Development 25th Anniversary Seminar Series.

    ERIC Educational Resources Information Center

    Hope, Nicholas C.

    Arguing that the benefits from borrowing abroad exceed the costs recently imposed on countries through debt-servicing difficulties, this paper defines debt as an engine of growth, forcing the borrower to produce goods efficiently, export them, and function competitively in the international market. Debt-servicing difficulties of developing nations…

  11. A resolution honoring the Blackstone Valley Tourism Council on the celebration of its 25th anniversary.

    THOMAS, 111th Congress

    Sen. Whitehouse, Sheldon [D-RI

    2010-03-24

    04/14/2010 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S2326) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  12. AIDS: The Global Impact. Academy for Educational Development 25th Anniversary Seminar Series.

    ERIC Educational Resources Information Center

    Mann, Jonathan

    This paper describes why acquired immune deficiency syndrome (AIDS) is a global health problem and discusses special features of the virus and its infection. This disease's transmission and interaction with other diseases, along with 1986 statistics concerning AIDS, are presented in terms of selected continents and countries. The World Health…

  13. Newspapers on Microfilm. Catalog and Price List 1971, 25th Anniversary Edition.

    ERIC Educational Resources Information Center

    1971

    Over 5500 current and backfile titles of American, foreign, and Black community newspapers that may be purchased on 35mm. roll microfilm are indexed in this catalog. Historical annotations are provided for selected American, Asian, and other foreign newspapers as well as for collections which focus on areas of special interest: early America, the…

  14. 25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine

    PubMed Central

    Annabi, Nasim; Tamayol, Ali; Uquillas, Jorge Alfredo; Akbari, Mohsen; Bertassoni, Luiz E.; Cha, Chaenyung; Camci-Unal, Gulden; Dokmeci, Mehmet R.

    2014-01-01

    Hydrogels are hydrophilic polymer-based materials with high water content and physical characteristics that resemble the native extracellular matrix. Because of their remarkable properties, hydrogel systems are used for a wide range of biomedical applications, such as three-dimensional (3D) matrices for tissue engineering, drug-delivery vehicles, composite biomaterials, and as injectable fillers in minimally invasive surgeries. In addition, the rational design of hydrogels with controlled physical and biological properties can be used to modulate cellular functionality and tissue morphogenesis. Here, the development of advanced hydrogels with tunable physiochemical properties is highlighted, with particular emphasis on elastomeric, light-sensitive, composite, and shape-memory hydrogels. Emerging technologies developed over the past decade to control hydrogel architecture are also discussed and a number of potential applications and challenges in the utilization of hydrogels in regenerative medicine are reviewed. It is anticipated that the continued development of sophisticated hydrogels will result in clinical applications that will improve patient care and quality of life. PMID:24741694

  15. 25th anniversary article: key points for high-mobility organic field-effect transistors.

    PubMed

    Dong, Huanli; Fu, Xiaolong; Liu, Jie; Wang, Zongrui; Hu, Wenping

    2013-11-20

    Remarkable progress has been made in developing high performance organic field-effect transistors (OFETs) and the mobility of OFETs has been approaching the values of polycrystalline silicon, meeting the requirements of various electronic applications from electronic papers to integrated circuits. In this review, the key points for development of high mobility OFETs are highlighted from aspects of molecular engineering, process engineering and interface engineering. The importance of other factors, such as impurities and testing conditions is also addressed. Finally, the current challenges in this field for practical applications of OFETs are further discussed. PMID:24105677

  16. 25th anniversary article: progress in chemistry and applications of functional indigos for organic electronics.

    PubMed

    Głowacki, Eric Daniel; Voss, Gundula; Sariciftci, Niyazi Serdar

    2013-12-17

    Indigo and its derivatives are dyes and pigments with a long and distinguished history in organic chemistry. Recently, applications of this 'old' structure as a functional organic building block for organic electronics applications have renewed interest in these molecules and their remarkable chemical and physical properties. Natural-origin indigos have been processed in fully bio-compatible field effect transistors, operating with ambipolar mobilities up to 0.5 cm(2) /Vs and air-stability. The synthetic derivative isoindigo has emerged as one of the most successful building-blocks for semiconducting polymers for plastic solar cells with efficiencies > 5%. Another isomer of indigo, epindolidione, has also been shown to be one of the best reported organic transistor materials in terms of mobility (∼2 cm(2) /Vs) and stability. This progress report aims to review very recent applications of indigoids in organic electronics, but especially to logically bridge together the hereto independent research directions on indigo, isoindigo, and other materials inspired by historical dye chemistry: a field which was the root of the development of modern chemistry in the first place. PMID:24151199

  17. Space Congress, 25th, Cocoa Beach, FL, Apr. 26-29, 1988, Proceedings

    SciTech Connect

    Not Available

    1988-01-01

    Papers are presented dealing with commercial aspects of space, space business, robotics, space station technologies, artificial intelligence applications in space, lunar and Mars exploration concepts, launch vehicles, and systems automation. Topics covered include ground processing of experiments conducted in space, the development of a commercial expendable launch vehicle industry, a small LEO satellite bus, epitaxial thin film growth in space, development of space enterprise, negotiating governmental contracts, robots in Shuttle hardware, telerobotic Space Station applications, simulation of an articulated transporter/manipulator system, welding the Space Station common module prototype, modeling the environment of the Man Tended Free Flyer, and Space Station rapid sample return. Ground operations support by AI, expert system prototype developments, Mars mission profile options and opportunities, launch vehicle operations analyses, space launch systems resiliency, model-based reasoning for knowledge-based software project management, technology advances for Space Shuttle processing, real-time fault management for large-scale systems, information systems for Shuttle processing, orbiter maneuvering vehicle support to the Space Station, and hydrogen-air-steam combustion regimes in large volumes are also discussed.

  18. GE Appliance Park Louisville, KY Plant Wide Assessment Final Report October 25th, 2007

    SciTech Connect

    Chandon Rao; Richard Urschel

    2007-10-25

    Used a team of experts to analyze and model major systems at a large industrial appliance manufacturer. During the data gathering stage, the team specifically looked for baselining the efficiency of the systems as well as developing short term and longer term efficiency projects. Electrical distribution, Compressed air generation and thermal heat recovery for the production facility and front office heating and cooling optimization were all baselined during the study.

  19. 25th anniversary article: CVD polymers: a new paradigm for surface modification and device fabrication.

    PubMed

    Coclite, Anna Maria; Howden, Rachel M; Borrelli, David C; Petruczok, Christy D; Yang, Rong; Yagüe, Jose Luis; Ugur, Asli; Chen, Nan; Lee, Sunghwan; Jo, Won Jun; Liu, Andong; Wang, Xiaoxue; Gleason, Karen K

    2013-10-11

    Well-adhered, conformal, thin (<100 nm) coatings can easily be obtained by chemical vapor deposition (CVD) for a variety of technological applications. Room temperature modification with functional polymers can be achieved on virtually any substrate: organic, inorganic, rigid, flexible, planar, three-dimensional, dense, or porous. In CVD polymerization, the monomer(s) are delivered to the surface through the vapor phase and then undergo simultaneous polymerization and thin film formation. By eliminating the need to dissolve macromolecules, CVD enables insoluble polymers to be coated and prevents solvent damage to the substrate. CVD film growth proceeds from the substrate up, allowing for interfacial engineering, real-time monitoring, and thickness control. Initiated-CVD shows successful results in terms of rationally designed micro- and nanoengineered materials to control molecular interactions at material surfaces. The success of oxidative-CVD is mainly demonstrated for the deposition of organic conducting and semiconducting polymers. PMID:24115244

  20. The Hawaii Undersea Research Laboratory's 25th Anniversary Expedition to the South Pacific

    NASA Astrophysics Data System (ADS)

    Smith, J. R.; Wiltshire, J. C.; Malahoff, A.

    2005-12-01

    The Hawaii Undersea Research Laboratory (HURL) was established by NOAA at the University of Hawaii 25 years ago as part of its National Undersea Research Program. HURL's mission is to study deep water marine processes in the Pacific Ocean through a competitive proposal and review process. The dual Pisces IV and Pisces V 2000-meter manned submersibles, an RCV-150 1000-meter ROV, and multibeam equipped support ship R/V Ka'imikai-o-Kanaloa ( KoK) were largely acquired from the petroleum industry then adapted and upgraded to carry out cutting edge scientific expeditions. These studies range from active submarine volcanoes, delicate precious coral gardens, endangered marine mammal and fisheries management, to engineering surveys and deployment of observatory systems. HURL successfully completed a major 5-month expedition to the South Pacific during March-August 2005, working in the waters of New Zealand, Tonga, American Samoa, and the U.S. Line Islands covering a distance of nearly 14,500 nautical miles. This mission was significant in both the scientific merit and scope of operations, consisting of 8 different cruise legs at 21 study sites, with 12 chief and co-chief scientists, 58 total science team participants, and completing 61 out of 56 scheduled Pisces science dives, 17 ROV dives, 5 multibeam survey areas, 6 CTD rosette deployments, and 7 instrument mooring recoveries. The $3.5 million expedition was funded by an international partnership with New Zealand agencies (GNS & NIWA) and the University of Kiel in Germany along with the NOAA Office of Exploration and National Undersea Research Program. While most of the individual cruise legs focused on active submarine volcanoes of the Tonga-Kermadec Islands Arc and the Samoan hot spot chain with their hydrothermal systems and associated biological communities, others concentrated on marine protected areas including those of American Samoa and the remote atolls of the Line Islands of the Central Pacific. These studies included biological habitat mapping, climate change from dating of precious coral growth rings, ecological inventory assessments, and the marine archeology and impact from a grounded vessel. An overview of the latter portion of the voyage will be presented, along with the general capabilities of the HURL systems, and how they may be utilized by others employing the international collaborative model for extended missions to remote locations in the pursuit of deep submergence science.

  1. 25th Anniversary Article: Organic Field-Effect Transistors: The Path Beyond Amorphous Silicon

    PubMed Central

    Sirringhaus, Henning

    2014-01-01

    Over the past 25 years, organic field-effect transistors (OFETs) have witnessed impressive improvements in materials performance by 3–4 orders of magnitude, and many of the key materials discoveries have been published in Advanced Materials. This includes some of the most recent demonstrations of organic field-effect transistors with performance that clearly exceeds that of benchmark amorphous silicon-based devices. In this article, state-of-the-art in OFETs are reviewed in light of requirements for demanding future applications, in particular active-matrix addressing for flexible organic light-emitting diode (OLED) displays. An overview is provided over both small molecule and conjugated polymer materials for which field-effect mobilities exceeding > 1 cm2 V–1 s–1 have been reported. Current understanding is also reviewed of their charge transport physics that allows reaching such unexpectedly high mobilities in these weakly van der Waals bonded and structurally comparatively disordered materials with a view towards understanding the potential for further improvement in performance in the future. PMID:24443057

  2. C-PORT Overview for ECOS/ASTHO July 25th, 2016

    EPA Science Inventory

    C-PORT initially developed in response to Region 4 concerns with NEPA assessments in port expansionsExpansion of Panama Canal prompted East and Gulf Coast ports to propose modernizations/expansionsEPA R4 reviewed Charleston EIS, but letter specifically asked for screening-level a...

  3. 25th anniversary of the deep manned submersibles Mir- 1 and Mir- 2

    NASA Astrophysics Data System (ADS)

    Sagalevitch, A. M.

    2012-11-01

    In 1987, the deep manned submersibles Mir- 1 and Mir- 2 were introduced into the practice of scientific research of the ocean. For 25 years, with their help, a wide range of deepwater operations have been carried out: oceanic scientific research (including the most active areas on the seabed—hydrothermal fields), shooting films and documentaries, which have brought international fame to the vehicles; special operations concerning solving problems of national importance concerning the sunken nuclear submarines Komsomolets and Kursk; live television broadcast from great depths of the ocean via satellite to the earth; diving under the ice at the geographic North Pole; a three-year cycle of scientific research on lake Baikal; etc. During the 25 years of their operation, there have been no unsolvable problems in the deep ocean for the Mir vehicles. They have rightfully taken a leading position in the field of deep-sea research in the world and were named the best vehicles in technical terms in the history of the creation of such technical facilities. Some of the results and details of the above-mentioned deep-sea operations, as well as the technical innovations developed and implemented during the service of the Mir vehicles, are considered in this article.

  4. [To the 25th anniversary of commencement of perestroika of national public health].

    PubMed

    Juravleva, T V; Khmel, A A

    2012-01-01

    The process of modernization of public health of the Russian Federation requires the application of experience of resent past. In 2012, is 25 years from the day of approval of the decree "The main directions of development of population health protection and perestroika of public health of the USSR in 12th five-year plan and to the period up to 2000". Many items of this document remained unrealized due to the change of social political course of country progression. Nevertheless, these items can be used presently to enhance the legislation in public health sector. PMID:23634616

  5. 25th anniversary article: carbon nanotube- and graphene-based transparent conductive films for optoelectronic devices.

    PubMed

    Du, Jinhong; Pei, Songfeng; Ma, Laipeng; Cheng, Hui-Ming

    2014-04-01

    Carbon nanotube (CNT)- and graphene (G)-based transparent conductive films (TCFs) are two promising alternatives for commonly-used indium tin oxide-based TCFs for future flexible optoelectronic devices. This review comprehensively summarizes recent progress in the fabrication, properties, modification, patterning, and integration of CNT- and G-TCFs into optoelectronic devices. Their potential applications and challenges in optoelectronic devices, such as organic photovoltaic cells, organic light emitting diodes and touch panels, are discussed in detail. More importantly, their key characteristics and advantages for use in these devices are compared. Despite many challenges, CNT- and G-TCFs have demonstrated great potential in various optoelectronic devices and have already been used for some products like touch panels of smartphones. This illustrates the significant opportunities for the industrial use of CNTs and graphene, and hence pushes nanoscience and nanotechnology one step towards practical applications. PMID:24591083

  6. 25th anniversary article: polymer-particle composites: phase stability and applications in electrochemical energy storage.

    PubMed

    Srivastava, Samanvaya; Schaefer, Jennifer L; Yang, Zichao; Tu, Zhengyuan; Archer, Lynden A

    2014-01-15

    Polymer-particle composites are used in virtually every field of technology. When the particles approach nanometer dimensions, large interfacial regions are created. In favorable situations, the spatial distribution of these interfaces can be controlled to create new hybrid materials with physical and transport properties inaccessible in their constituents or poorly prepared mixtures. This review surveys progress in the last decade in understanding phase behavior, structure, and properties of nanoparticle-polymer composites. The review takes a decidedly polymers perspective and explores how physical and chemical approaches may be employed to create hybrids with controlled distribution of particles. Applications are studied in two contexts of contemporary interest: battery electrolytes and electrodes. In the former, the role of dispersed and aggregated particles on ion-transport is considered. In the latter, the polymer is employed in such small quantities that it has been historically given titles such as binder and carbon precursor that underscore its perceived secondary role. Considering the myriad functions the binder plays in an electrode, it is surprising that highly filled composites have not received more attention. Opportunities in this and related areas are highlighted where recent advances in synthesis and polymer science are inspiring new approaches, and where newcomers to the field could make important contributions. PMID:24323839

  7. Cartography and Connectomes Perspective article for Neuron 25th Anniversary Issue

    PubMed Central

    Van Essen, David C.

    2013-01-01

    The past 25 years have seen great progress in parcellating the cerebral cortex into a mosaic of many distinct areas in mice, monkeys, and humans. Quantitative studies of inter-areal connectivity have revealed unexpectedly many pathways and a wide range of connection strengths in mouse and macaque cortex. In humans, advances in analyzing ‘structural’ and ‘functional’ connectivity using powerful but indirect noninvasive neuroimaging methods are yielding intriguing insights about brain circuits, their variability across individuals, and their relationship to behavior. PMID:24183027

  8. National Center for Biotechnology Information Celebrates 25th Anniversary | NIH MedlinePlus the Magazine

    MedlinePlus

    ... http://m.medlineplus.gov/spanish Tune in: NIH Radio Free podcast audio reports on your computer or personal audio player www.nih.gov/news/radio/nihpodcast.htm Winter 2014 Issue: Volume 8 Number ...

  9. Introductory address by Dr Demissie Habte on the occasion of the 25th anniversary of ORS.

    PubMed

    Habte, D

    1994-01-01

    In Bangladesh, the director of the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) gave the introductory address at an awards ceremony to celebrate its key role in the discovery of oral rehydration solution (ORS) 25 years ago. ORS, a simple and affordable treatment for diarrheal disease, has specific amounts of glucose, salts, and water. Oral rehydration therapy (ORT) includes ORS and other solutions made with effective and safe salt concentrations and cereals. In South Asia, rock salt with cooked rice in a thick gruel was used to treat diarrhea as long as 3000 years ago. Researchers at the Cholera Research Laboratory in Dhaka during 1964-1968 learned that adding glucose to a solution of salts greatly helps the intestine's ability to absorb water and electrolytes, and that the intestine could absorb them during acute diarrhea. In November, 1987, the researchers set up a large scale field treatment center at a hospital in Malumghat, between Cox's Bazaar and Chittagong. It treated more than 300 cholera patients. No one died, but the trial was a failure. The researchers designed another clinical trial which showed that ORS reduced the need for intravenous fluids by 75% when treating acute cholera in adults. Another ORS trial in Calcutta yielded the same results. The laboratory also showed that ORS alone could rehydrate people with acute dehydrating diarrhea and that medical auxiliaries could administer it. In 1971, ORS successfully treated Bangladeshi refugees with cholera. The international health community officially accepted ORT in 1978. In developed countries, the potential health care cost savings of ORS use is greater than a few billion dollars at the very least and US$ 10-15 billion from optimal ORS use. Government officials from what is now Bangladesh and the US established the Cholera Research Laboratory 32 years ago. 18 years later, it became ICDDR,B. We must recognize the miracle of ORS. PMID:12345476

  10. 1984-2008. Predictions for Higher Education. From the 25th Anniversary Colloquium. [Proceedings].

    ERIC Educational Resources Information Center

    Hardee, Melvene Draheim, Ed.

    Predictions on higher education for 1984-2009 are presented in the proceedings of a colloquium of the Institute for Studies in Higher Education of Florida State University. Presentations were made at the colloquium by 10 graduates of the university whose current positions represent administration-management, instruction, research, and student…

  11. KIDS COUNT Data Book, 2014: State Trends in Child Well-Being. 25th Edition

    ERIC Educational Resources Information Center

    Annie E. Casey Foundation, 2014

    2014-01-01

    Each year since 1990, the Annie E. Casey Foundation has published the KIDS COUNT Data Book to track the well-being of children nationally and in every state. When the first Data Book was launched 25 years ago, the hope was that it would raise public awareness and build public commitment to invest in solutions to ensure that each and every child…

  12. 25th Anniversary Article: Ordered Polymer Structures for the Engineering of Photons and Phonons

    PubMed Central

    Lee, Jae-Hwang; Koh, Cheong Yang; Singer, Jonathan P; Jeon, Seog-Jin; Maldovan, Martin; Stein, Ori; Thomas, Edwin L

    2014-01-01

    The engineering of optical and acoustic material functionalities via construction of ordered local and global architectures on various length scales commensurate with and well below the characteristic length scales of photons and phonons in the material is an indispensable and powerful means to develop novel materials. In the current mature status of photonics, polymers hold a pivotal role in various application areas such as light-emission, sensing, energy, and displays, with exclusive advantages despite their relatively low dielectric constants. Moreover, in the nascent field of phononics, polymers are expected to be a superior material platform due to the ability for readily fabricated complex polymer structures possessing a wide range of mechanical behaviors, complete phononic bandgaps, and resonant architectures. In this review, polymer-centric photonic and phononic crystals and metamaterials are highlighted, and basic concepts, fabrication techniques, selected functional polymers, applications, and emerging ideas are introduced. PMID:24338738

  13. EDITORIAL: Special issue in honour of J E Allen's 75th birthday

    NASA Astrophysics Data System (ADS)

    Franklin, R. N.

    2003-11-01

    This issue of Journal of Physics D: Applied Physics is dedicated to Professor John Allen who has spent most of his professional life in the Department of Engineering Science, Oxford University, working on problems in gas discharges and plasma physics. His first degrees and doctorate were taken at Liverpool University in the 1950s where at the time there was an internationally renowned group led by Meek, Craggs and Edels. He then spent some time at Frascati in Italy on secondment from Harwell, helping to build up expertise there. He returned to England in the mid-1960s, first to Cambridge, but he soon migrated to Oxford to University College and the Department of Engineering Science to strengthen a team that already included von Engel, Motz and Woods with more recent reinforcement by Howatson and myself. Thus there was built up both a post-graduate MSc course and what amounted to a graduate school producing many scientists who have since distinguished themselves in all parts of the world. The prospects for success in the quest for fusion and the proximity of Culham Laboratory produced a heady mix. But the timescales lengthened and fashions changed. However, John moved with the times and he and his research students made notable contributions to the understanding of dusty plasmas and to radio-frequency plasmas used in the processing of microchips. The structure at Oxford was such that the recognition of a professorship came late in his career, but his international reputation was well established much earlier. Being freed of tutorial duties he has travelled much in recent years and has been Chairman of the International Conference on Phenomena in Ionized Gases (ICPIG) 1999-2001 and directly involved in the international effort to carry out dusty plasma experiments in space under micro-gravity conditions. For my part, having known John as a colleague over the past forty years, he has been a valuable point of reference when one needed someone to comment on new ideas, a challenging competitor when we were working on similar lines, and his research students provided me with the stimulation that comes from such interaction, be it informal or more formally in the course of D Phil vivas. Thus I have felt that there was a debt to be repaid by encouraging his students and other co-workers to contribute to this issue. More importantly, we honour someone whose contributions we know will stand the test of time.

  14. A resolution commemorating the 75th Anniversary of Air Force Weather.

    THOMAS, 112th Congress

    Sen. Johanns, Mike [R-NE

    2012-08-02

    08/02/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6012-6013; text as passed Senate: CR S6012; text of measure as introduced: CR S5992) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  15. Symposium for Alfred Wolf's 75th birthday at American Chemical Society meeting

    SciTech Connect

    1998-04-02

    This report contains abstracts from the symposium presented by the Division of Nuclear Chemistry and Technology of the American Chemical Society. Sessions covered the following topics: Therapeutic radionuclides--Making the right choice; Aspects of nuclear science; Nuclear structure with large gamma-ray detector arrays and their auxiliary devices; Thirty years of research in nuclear dynamics--From fission to the quark-gluon plasma; Chelated metal ions for diagnosis and therapy; Radiochemistry--Basic and applied; and Applications of small accelerators in science and industry.

  16. A resolution congratulating the Soil Science Society of America on its 75th anniversary.

    THOMAS, 112th Congress

    Sen. Moran, Jerry [R-KS

    2011-06-30

    06/30/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S4304-4305; text as passed Senate: CR S4304-4305; text of measure as introduced: CR S4298) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  17. A concurrent resolution commemorating the 75th anniversary of the dedication of Shenandoah National Park.

    THOMAS, 112th Congress

    Sen. Webb, Jim [D-VA

    2011-06-23

    06/23/2011 Referred to the Committee on Energy and Natural Resources. (text of measure as introduced: CR S4104) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  18. A resolution commemorating the 75th anniversary of the dedication of Shenandoah National Park.

    THOMAS, 112th Congress

    Sen. Webb, Jim [D-VA

    2011-09-08

    09/08/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR: S5465; text as passed Senate: CR S5465; text of measure as introduced: CR S5463) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  19. A resolution commemorating the 75th anniversary of Kristallnacht, or the Night of the Broken Glass.

    THOMAS, 113th Congress

    Sen. Cardin, Benjamin L. [D-MD

    2013-11-12

    11/12/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S7964; text as passed Senate: CR S7962) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  20. Development of a quantitative food frequency questionnaire for Brazilian patients with type 2 diabetes

    PubMed Central

    2013-01-01

    Background To investigate the association between dietary components and development of chronic diabetic complications, the dietary evaluation should include a long period, months or years. The present manuscript aims to develop a quantitative food frequency questionnaire (FFQ) and a portfolio with food photos to assess the usual intake pattern of Brazilian patients with type 2 diabetes to be used in future studies. Methods Dietary data using 3-day weighed diet records (WDR) from 188 outpatients with type 2 diabetes were used to construct the list of usually consumed foods. Foods were initially clustered into eight groups: “cereals, tubers, roots, and derivatives”; “vegetables and legumes”; “fruits”; “beans”; “meat and eggs”; “milk and dairy products”; “oils and fats”, and “sugars and sweets”. The frequency of food intake and the relative contribution of each food item to the total energy and nutrient intakes were calculated. Portion sizes were determined according to the 25th, 50th, 75th, and 95th percentiles of intake for each food item. Results A total of 62 food items were selected based on the 3-day WDR and another 27 foods or how they are prepared and nine beverages were included after the expert examination. Also, a portfolio with food photos of each included food item and portion sizes was made to assist the patients in identifying the consumed portion. Conclusions We developed a practical quantitative FFQ and portfolio with photos of 98 food items covering those most commonly consumed in the past 12 months, to assess the usual diet pattern of patients with type 2 diabetes in Southern Brazil. PMID:23938026

  1. Variability in early communicative development.

    PubMed

    Fenson, L; Dale, P S; Reznick, J S; Bates, E; Thal, D J; Pethick, S J

    1994-01-01

    Data from parent reports on 1,803 children--derived from a normative study of the MacArthur Communicative Development Inventories (CDIs)--are used to describe the typical course and the extent of variability in major features of communicative development between 8 and 30 months of age. The two instruments, one designed for 8-16-month-old infants, the other for 16-30-month-old toddlers, are both reliable and valid, confirming the value of parent reports that are based on contemporary behavior and a recognition format. Growth trends are described for children scoring at the 10th-, 25th-, 50th-, 75th-, and 90th-percentile levels on receptive and expressive vocabulary, actions and gestures, and a number of aspects of morphology and syntax. Extensive variability exists in the rate of lexical, gestural, and grammatical development. The wide variability across children in the time of onset and course of acquisition of these skills challenges the meaningfulness of the concept of the modal child. At the same time, moderate to high intercorrelations are found among the different skills both concurrently and predictively (across a 6-month period). Sex differences consistently favor females; however, these are very small, typically accounting for 1%-2% of the variance. The effects of SES and birth order are even smaller within this age range. The inventories offer objective criteria for defining typicality and exceptionality, and their cost effectiveness facilitates the aggregation of large data sets needed to address many issues of contemporary theoretical interest. The present data also offer unusually detailed information on the course of development of individual lexical, gestural, and grammatical items and features. Adaptations of the CDIs to other languages have opened new possibilities for cross-linguistic explorations of sequence, rate, and variability of communicative development. PMID:7845413

  2. An Administrative Claims Model for Profiling Hospital 30-Day Mortality Rates for Pneumonia Patients

    PubMed Central

    Bratzler, Dale W.; Normand, Sharon-Lise T.; Wang, Yun; O'Donnell, Walter J.; Metersky, Mark; Han, Lein F.; Rapp, Michael T.; Krumholz, Harlan M.

    2011-01-01

    Background Outcome measures for patients hospitalized with pneumonia may complement process measures in characterizing quality of care. We sought to develop and validate a hierarchical regression model using Medicare claims data that produces hospital-level, risk-standardized 30-day mortality rates useful for public reporting for patients hospitalized with pneumonia. Methodology/Principal Findings Retrospective study of fee-for-service Medicare beneficiaries age 66 years and older with a principal discharge diagnosis of pneumonia. Candidate risk-adjustment variables included patient demographics, administrative diagnosis codes from the index hospitalization, and all inpatient and outpatient encounters from the year before admission. The model derivation cohort included 224,608 pneumonia cases admitted to 4,664 hospitals in 2000, and validation cohorts included cases from each of years 1998–2003. We compared model-derived state-level standardized mortality estimates with medical record-derived state-level standardized mortality estimates using data from the Medicare National Pneumonia Project on 50,858 patients hospitalized from 1998–2001. The final model included 31 variables and had an area under the Receiver Operating Characteristic curve of 0.72. In each administrative claims validation cohort, model fit was similar to the derivation cohort. The distribution of standardized mortality rates among hospitals ranged from 13.0% to 23.7%, with 25th, 50th, and 75th percentiles of 16.5%, 17.4%, and 18.3%, respectively. Comparing model-derived risk-standardized state mortality rates with medical record-derived estimates, the correlation coefficient was 0.86 (Standard Error = 0.032). Conclusions/Significance An administrative claims-based model for profiling hospitals for pneumonia mortality performs consistently over several years and produces hospital estimates close to those using a medical record model. PMID:21532758

  3. Optimizing Display, Analysis, Interpretation and Utility of Self-Monitoring of Blood Glucose (SMBG) Data for Management of Patients with Diabetes

    PubMed Central

    Rodbard, David

    2007-01-01

    Background Self-monitoring of blood glucose (SMBG) data have not been used to fullest advantage. Few physicians routinely download data from memory-equipped glucose meters and perform systematic analyses and interpretation of the data. There is need for improved methods for display and analysis of SMBG data, for a systematic approach for identification and prioritization of clinical problems revealed by SMBG, for characterization of blood glucose variability, and for clinical decision support. Methods We have developed a systematic approach to the analysis and interpretation of SMBG data to assist in the management of patients with diabetes. This approach utilizes the following criteria: 1) Overall quality of glycemic control; 2) Hypoglycemia (frequency, severity, timing); 3) Hyperglycemia; 4) Variability; 5) Pattern analysis; and 6) Adequacy of monitoring. The “Pattern analysis” includes assessment of: trends by date and by time of day; relationship of blood glucose to meals; post-prandial excursions; the effects of day of the week, and interactions between time of day and day of the week. Results The asymmetrical distribution of blood glucose values makes it difficult to interpret the mean and standard deviation. Use of the median (50th percentile) and Inter-Quartile Range (IQR) overcomes these difficulties: IQR is the difference between the 75th and 25th percentiles. SMBG data can be used to predict the A1c level and indices of the risks of hyperglycemia and hypoglycemia. Conclusion Given reliable measures of glucose variability, one can apply a strategy to progressively reduce glucose variability and then increase the intensity of therapy so as to reduce median blood glucose and hence A1c, while minimizing the risk of hypoglycemia. PMID:19888382

  4. Reference Values for Body Composition and Anthropometric Measurements in Athletes

    PubMed Central

    Santos, Diana A.; Dawson, John A.; Matias, Catarina N.; Rocha, Paulo M.; Minderico, Cláudia S.; Allison, David B.; Sardinha, Luís B.; Silva, Analiza M.

    2014-01-01

    Background Despite the importance of body composition in athletes, reference sex- and sport-specific body composition data are lacking. We aim to develop reference values for body composition and anthropometric measurements in athletes. Methods Body weight and height were measured in 898 athletes (264 female, 634 male), anthropometric variables were assessed in 798 athletes (240 female and 558 male), and in 481 athletes (142 female and 339 male) with dual-energy X-ray absorptiometry (DXA). A total of 21 different sports were represented. Reference percentiles (5th, 25th, 50th, 75th, and 95th) were calculated for each measured value, stratified by sex and sport. Because sample sizes within a sport were often very low for some outcomes, the percentiles were estimated using a parametric, empirical Bayesian framework that allowed sharing information across sports. Results We derived sex- and sport-specific reference percentiles for the following DXA outcomes: total (whole body scan) and regional (subtotal, trunk, and appendicular) bone mineral content, bone mineral density, absolute and percentage fat mass, fat-free mass, and lean soft tissue. Additionally, we derived reference percentiles for height-normalized indexes by dividing fat mass, fat-free mass, and appendicular lean soft tissue by height squared. We also derived sex- and sport-specific reference percentiles for the following anthropometry outcomes: weight, height, body mass index, sum of skinfold thicknesses (7 skinfolds, appendicular skinfolds, trunk skinfolds, arm skinfolds, and leg skinfolds), circumferences (hip, arm, midthigh, calf, and abdominal circumferences), and muscle circumferences (arm, thigh, and calf muscle circumferences). Conclusions These reference percentiles will be a helpful tool for sports professionals, in both clinical and field settings, for body composition assessment in athletes. PMID:24830292

  5. A methodology to study multiple sclerosis (MS) based on distributions of standardized intensities in segmented tissue regions

    NASA Astrophysics Data System (ADS)

    Lei, T.; Udupa, J. K.; Odhner, D.; Mishra, S.; Wu, G.; Schwartz, E.; Ying, G.-S.; Iwanaga, T.; Desiderio, L.; Balcer, L.

    2006-03-01

    This paper presents (1) an improved hierarchical method for segmenting the component tissue regions in fast spin echo T2 and PD images of the brain of Multiple Sclerosis (MS) patients, and (2) a methodology to characterize the disease utilizing the distributions of standardized T2 and PD intensities in the segmented tissue regions. First, the background intensity inhomogeneities are corrected and the intensity scales are standardized for all acquired images. The segmentation method imposes a feedback-like procedure on our previously developed hierarchical brain tissue segmentation method. With gradually simplified patterns in images and stronger evidences, pathological objects are recognized and segmented in an interplay fashion. After the brain parenchymal (BP) mask is generated, an under-estimated gray matter mask (uGM) and an over-estimated white matter mask (oWM) are created. Pure WM (PWM) and lesion (LS) masks are extracted from the all-inclusive oWM mask. By feedback, accurate GM and WM masks are subsequently formed. Finally, partial volume regions of GM and WM as well as Dirty WM (DWM) masks are generated. Intensity histograms and their parameters (peak height, peak location, and 25th, 50th and 75th percentile values) are computed for both T2 and PD images within each tissue region. Tissue volumes are also estimated. Spearman correlation coefficient rank test is then utilized to assess if there exists a trend between clinical states and the image-based parameters. This image analysis method has been applied to a data set consisting of 60 patients with MS and 20 normal controls. LS related parameters and clinical Extended Disability Status Scale (EDSS) scores demonstrate modest correlations. Almost every intensity-based parameter shows statistical difference between normal control and patient groups with a level better than 5%. These results can be utilized to monitor disease progression in MS.

  6. A Streamflow Statistics (StreamStats) Web Application for Ohio

    USGS Publications Warehouse

    Koltun, G.F.; Kula, Stephanie P.; Puskas, Barry M.

    2006-01-01

    A StreamStats Web application was developed for Ohio that implements equations for estimating a variety of streamflow statistics including the 2-, 5-, 10-, 25-, 50-, 100-, and 500-year peak streamflows, mean annual streamflow, mean monthly streamflows, harmonic mean streamflow, and 25th-, 50th-, and 75th-percentile streamflows. StreamStats is a Web-based geographic information system application designed to facilitate the estimation of streamflow statistics at ungaged locations on streams. StreamStats can also serve precomputed streamflow statistics determined from streamflow-gaging station data. The basic structure, use, and limitations of StreamStats are described in this report. To facilitate the level of automation required for Ohio's StreamStats application, the technique used by Koltun (2003)1 for computing main-channel slope was replaced with a new computationally robust technique. The new channel-slope characteristic, referred to as SL10-85, differed from the National Hydrography Data based channel slope values (SL) reported by Koltun (2003)1 by an average of -28.3 percent, with the median change being -13.2 percent. In spite of the differences, the two slope measures are strongly correlated. The change in channel slope values resulting from the change in computational method necessitated revision of the full-model equations for flood-peak discharges originally presented by Koltun (2003)1. Average standard errors of prediction for the revised full-model equations presented in this report increased by a small amount over those reported by Koltun (2003)1, with increases ranging from 0.7 to 0.9 percent. Mean percentage changes in the revised regression and weighted flood-frequency estimates relative to regression and weighted estimates reported by Koltun (2003)1 were small, ranging from -0.72 to -0.25 percent and -0.22 to 0.07 percent, respectively.

  7. Geochemical signatures of possible deep-seated ore deposits in Tertiary volcanic centers, Arizona and New Mexico, U.S.A.

    USGS Publications Warehouse

    Watts, K.C., Jr.; Hassemer, J.R.

    1989-01-01

    A reconnaissance geochemical survey of stream drainages within 21,000 km2 of southeastern Arizona and southwestern New Mexico shows broad zones of low-level to moderate contrast anomalies, many associated with mid-Tertiary eruptive centers and Tertiary fault zones. Of these eruptive centers, few are known to contain metallic deposits, and most of those known are minor. This, however, may be more a function of shallow erosion level than an indication of the absence of mineralization, since hydrothermal alteration and Fe-Mn-oxide staining are widespread, and geochemical anomalies are pervasive over a larger part of the region than outcrop observations would predict. Accordingly, interpretations of the geochemical data use considerations of relative erosion levels, and inferred element zonalities, to focus on possible undiscovered deposits in the subsurface of base-, precious-, and rare-metal deposits of plutonic-volcanic association. In order to enhance the identification of specific deep targets, we use the empirically determined ratio: Ag+Mn+Pb+Zn+Ba Au+Mo+Cu+Bi+W This ratio is based on reported metal contents of nonmagnetic heavy-mineral samples from the drainage sediment, determined by emission spectrographic analysis. Before the ratio was computed for each sample site, the data were normalized to a previously estimated regional threshold value. A regional isopleth map was then prepared, using a cell-averaging computer routine, with contours drawn at the 25th, 50th, 75th, 80th, 90th, 95th and 99th percentiles of the computed data. ?? 1989.

  8. Influence of Race/Ethnicity, Body Mass Index, and Proximity of Menopause on Menstrual Cycle Patterns in the Menopausal Transition: The Study of Women’s Health Across the Nation (SWAN)

    PubMed Central

    Paramsothy, Pangaja; Harlow, Siobán D.; Elliott, Michael R.; Yosef, Matheos; Lisabeth, Lynda D.; Greendale, Gail A.; Gold, Ellen B.; Crawford, Sybil L.; Randolph, John F.

    2014-01-01

    Objective Few studies evaluate factors that influence menstrual cycle length (MCL) during the menopausal transition (MT), a life-stage during which very long cycles become more likely to occur. The objective of this paper was to assess how BMI and race/ethnicity, factors associated with MCL in young women, influence MCL during the MT. Methods SWAN Menstrual Calendar Substudy data were available from 3 sites (southeastern Michigan, Los Angeles, and northern California) including African-American, White, Chinese, and Japanese women. Self-recorded monthly menstrual calendars with end of the month questions on hormone therapy use and smoking were collected from 1996–2006. Height and weight were measured at annual study visits. We used quantile regression to model MCL at the 25th, 50th, 75th, and 90th percentiles with bootstrap sampling to construct 95% confidence intervals. Models evaluated MCL with time indexed to the start of the MT (n=963) and to the final menstrual period (n=431). Results During the MT, increases in MCL occurred mostly in the right tail of the distribution, reflecting a lengthening of long menstrual cycles not of the median MCL. After adjusting for smoking, education, physical activity, and time, Chinese and Japanese women had 1–6 day longer MCLs as compared to White women. Obese women had 1–5 day longer MCLs as compared to non-obese women. Conclusions As occurs in younger women, menstrual characteristics during the MT are influenced by race/ethnicity and obesity. The long menstrual cycles characteristic of the MT are longer in obese women and in Chinese and Japanese women. PMID:25026113

  9. Technical note: Relationship between infrared thermography and heat production in young bulls.

    PubMed

    Gomes, R A; Busato, K C; Ladeira, M M; Johnson, K A; Galvão, M C; Rodrigues, A C; Lourençoni, D; Chizzotti, M L

    2016-03-01

    The traditional techniques to measure heat production (HP) are calorimetry (direct and indirect) and comparative slaughter. Both methods are expensive and require extensive amounts of time and infrastructure. Infrared thermography (IRT) could be a faster and less expensive alternative to estimate cattle HP. The objective of this project was to evaluate the use of the IRT technique as an indicator of HP in cattle. A total of 24 bulls (12 Nellore and 12 Black Angus) with initial BW of 380 ± 7 kg were used. Initially, 4 animals of each breed were harvested (baseline animals) and simple regressions were developed for each breed from these baseline animals to estimate the initial chemical composition of the remaining bulls. Eight animals of each breed were fed a silage/concentrate diet for ad libitum intake in individual stalls. On the 25th, 50th, and 75th experimental day, infrared thermal images (Fluke Ti 55ft; Fluke Corporation) were taken of each animal's face to access skin and ocular surface temperatures. A metabolism trial was conducted to estimate the ME intake (MEI). After 84 experimental days, the cattle were harvested and retained energy (RE) and HP were calculated. The data were analyzed using the MIXED and REG procedures of SAS adopting a significance level of 0.05. Angus cattle had a greater daily MEI, HP, and skin and eye temperatures than Nellore. We found significant correlations ( ≤ 0.005) between daily HP and maximum ( = 0.65) and average skin temperatures ( = 0.65) and maximum ( = 0.65) and average ocular surface ( = 0.69) temperatures recorded on d 50. Infrared thermography has potential to be used to evaluate HP in cattle. PMID:27065272

  10. Differential association of cardiorespiratory fitness and central adiposity among US adolescents and adults: A quantile regression approach.

    PubMed

    McDonald, Samantha M; Ortaglia, Andrew; Bottai, Matteo; Supino, Christina

    2016-07-01

    Previous studies assessing the association between cardiorespiratory fitness (CRF) and waist circumference (WC) have often restricted their evaluation to the association of CRF on average WC. Consequently, the assessment of important variations in the relationship of CRF across the WC distribution was precluded. The purpose of this study was to comprehensively evaluate the association between CRF and the distribution of WC using quantile regression. Secondary data analysis was conducted using data from the 1999-2004 NHANES. Participants (n=8260) aged 12-49years with complete data on estimated maximal oxygen consumption and WC were included. Quantile regression models were performed to assess the association between CRF and the 10th, 25th, 50th, 75th and 90th WC percentiles and were adjusted for age and race/ethnicity. For male and female adolescents with high CRF compared to low-fit counterparts, significant negative estimates (2.8 to 20.2cm and 2.3 to 11.2cm, respectively) were observed across most WC percentiles. Similarly, among male and female adults, high CRF was associated with significant reductions in WC across all percentiles (9.5 to 12.0cm and 3.7 to 9.2cm, respectively). For both populations, an increasing trend in the magnitude of the association of high CRF across the WC percentiles was observed. CRF appears to have a differential relationship across the WC distribution with the largest reductions in WC were found among high-fit individuals with the greatest amount of central adiposity (WC≥90th percentile). Additionally, this differential association highlights the significant limitations of statistical techniques used in previous analyses which focused on the center of the distribution. PMID:27002254

  11. Comparison of Simulated Workplace Protection Factors Offered by N95 and P100 Filtering Facepiece and Elastomeric Half-Mask Respirators against Particles of 10 to 400 nm

    PubMed Central

    He, Xinjian; Vo, Evanly; Horvatin, M; Liu, Y; Bergman, M; Zhuang, Z

    2015-01-01

    This study compared the simulated workplace protection factors (SWPFs) between NIOSH-approved N95 respirators and P100 respirators, including two models of filtering facepiece respirator (FFR) and two models of elastomeric half-mask respirator (EHR), against sodium chloride particles (NaCl) in a range of 10 to 400 nm. Twenty-five human test subjects performed modified OSHA fit test exercises in a controlled laboratory environment with the N95 respirators (two FFR models and two EHR models) and the P100 respirators (two FFRs and two EHRs). Two Scanning Mobility Particle Sizers (SMPS) were used to measure aerosol concentrations (in the 10–400 nm size range) inside (Cin) and outside (Cout) of the respirator, simultaneously. SWPF was calculated as the ratio of Cout to Cin. The SWPF values obtained from the N95 respirators were then compared to those of the P100 respirators. SWPFs were found to be significantly different (P<0.05) between N95 and P100 class respirators. The 10th, 25th, 50th, 75th and 90th percentiles of the SWPFs for the N95 respirators were much lower than those for the P100 models. The N95 respirators had 5th percentiles of the SWPFs > 10. In contrast, the P100 class was able to generate 5th percentiles SWPFs > 100. No significant difference was found in the SWPFs when tested against nano-size (10 to 100 nm) and large-size (100 to 400 nm) particles. Overall, the findings suggest that the two FFRs and two EHRs with P100 class filters provide better performance than those with N95 filters against particles from 10 to 400 nm, supporting current OSHA and NIOSH recommendations. PMID:26273701

  12. Relationship of adiposity to the population distribution of plasma triglyceride concentrations in vigorously active men and women

    SciTech Connect

    Williams, Paul T.

    2002-12-21

    Context and Objective: Vigorous exercise, alcohol and weight loss are all known to increase HDL-cholesterol, however, it is not known whether these interventions raise low HDL as effectively as has been demonstrated for normal HDL. Design: Physician-supplied medical data from 7,288 male and 2,359 female runners were divided into five strata according to their self-reported usual running distance, reported alcohol intake, body mass index (BMI) or waist circumference. Within each stratum, the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles for HDL-cholesterol were then determined. Bootstrap resampling of least-squares regression was applied to determine the cross-sectional relationships between these factors and each percentile of the HDL-cholesterol distribution. Results: In both sexes, the rise in HDL-cholesterol per unit of vigorous exercise or alcohol intake was at least twice as great at the 95th percentile as at the 5th percentile of the HDL-distribution. There was also a significant graded increase in the slopes relating exercise (km run) and alcohol intake to HDL between the 5th and the 95th percentile. Men's HDL-cholesterol decreased in association with fatness (BMI and waist circumference) more sharply at the 95th than at the 5th percentile of the HDL-distribution. Conclusions: Although exercise, alcohol and adiposity were all related to HDL-cholesterol, the elevation in HDL per km run or ounce of alcohol consumed, and reduction in HDL per kg of body weight (men only), was least when HDL was low and greatest when HDL was high. These cross-sectional relationships support the hypothesis that men and women who have low HDL-cholesterol will be less responsive to exercise and alcohol (and weight loss in men) as compared to those who have high HDL-cholesterol.

  13. Landau ghost pole problem in quantum field theory: From 50th of last century to the present day

    NASA Astrophysics Data System (ADS)

    Jafarov, Rauf G.; Mutallimov, Mutallim M.

    2016-03-01

    In this paper we present our results of the investigation of asymptotical behavior of amplitude at short distances in four-dimensional scalar field theory with ϕ4 interaction. To formulate of our calculating model - two-particle approximation of the mean-field expansion we have used an Rochev's iteration scheme of solution of the Schwinger-Dyson equations with the fermion bilocal source. We have considered the nonlinear integral equations in deep-inelastic region of momenta. As result we have a non-trivial behavior of amplitude at large momenta.

  14. Remembering Charles B. Huggins' Nobel Prize for Hormonal Treatment of Prostatic Cancer at its 50th Anniversary.

    PubMed

    Hansson, Nils; Moll, Friedrich; Schultheiss, Dirk; Krischel, Matthis

    2016-06-01

    Charles B. Huggins received the Nobel Prize in 1966. Based on archival sources from the Nobel archive we have found that nominators emphasised the practical therapeutic applications of his discoveries that were showing 25 yr after his key publications. PMID:26838478

  15. 3 CFR 8759 - Proclamation 8759 of November 21, 2011. 50th Anniversary of the United States Agency for...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... developing world and the American people. Since President John F. Kennedy founded USAID in 1961, the men and... countries as they build a better future. By promoting sustainable growth in the developing world, we spur... conflict around the world. Even after these successes, we know there is more to do. To advance...

  16. A resolution recognizing the 50th anniversary of the sinking of the U.S.S. Thresher (SSN 593).

    THOMAS, 113th Congress

    Sen. Shaheen, Jeanne [D-NH

    2013-04-09

    04/09/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2508; text as passed Senate: CR S2507) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  17. Happy 50th Birthday Smokey Bear! A Learning Kit about Forests and Fire Safety for Grades K-3.

    ERIC Educational Resources Information Center

    Hall, Meryl

    For over 50 years, the primary goal of Smokey Bear has been to introduce the forest fire prevention message to young children. This learning kit provides the K-3 teacher with activities and resources to help students learn about Smokey Bear and fire safety, about forests as habitats, and about what they can do to protect forests. Students are…

  18. Dosimetric impacts of microgravity: an analysis of 5th, 50th and 95th percentile male and female astronauts

    NASA Astrophysics Data System (ADS)

    Bahadori, Amir A.; Van Baalen, Mary; Shavers, Mark R.; Semones, Edward J.; Bolch, Wesley E.

    2012-02-01

    Computational phantoms serve an important role in organ dosimetry and risk assessment performed at the National Aeronautics and Space Administration (NASA). A previous study investigated the impact on organ dose equivalents and effective doses from the use of the University of Florida hybrid adult male (UFHADM) and adult female (UFHADF) phantoms at differing height and weight percentiles versus those given by the two existing NASA phantoms, the computerized anatomical man (CAM) and female (CAF) (Bahadori et al 2011 Phys. Med. Biol. 56 1671-94). In the present study, the UFHADM and UFHADF phantoms of different body sizes were further altered to incorporate the effects of microgravity. Body self-shielding distributions are generated using the voxel-based ray tracer (VoBRaT), and the results are combined with depth dose data from the NASA codes BRYNTRN and HZETRN to yield organ dose equivalents and their rates for a variety of space radiation environments. It is found that while organ dose equivalents are indeed altered by the physiological effects of microgravity, the magnitude of the change in overall risk (indicated by the effective dose) is minimal for the spectra and simplified shielding configurations considered. The results also indicate, however, that UFHADM and UFHADF could be useful in designing dose reduction strategies through optimized positioning of an astronaut during encounters with solar particle events.

  19. Reflections on the 50th Anniversary of the Landmark Decision. Brown v. Board of Education. Info Brief. Number 37

    ERIC Educational Resources Information Center

    Laitsch, Dan; Rodi, Katherine G.

    2004-01-01

    In the 50 years since "Brown v. Board of Education of Topeka" formally desegregated public schools, there has been enormous progress in the academic success of African Americans, particularly in high school completion, improved test scores, increased college enrollment, and attainment of advanced degrees, as well as full access to and…

  20. A resolution commemorating John Lewis on the 50th anniversary of his chairmanship of the Student Nonviolent Coordinating Committee.

    THOMAS, 113th Congress

    Sen. Isakson, Johnny [R-GA

    2013-06-13

    06/19/2013 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  1. The 50th Anniversary of Brown v. Board of Education: Continued Impacts on Minority Life Science Education

    ERIC Educational Resources Information Center

    Ricks, Irelene

    2004-01-01

    This article provides a brief history of affirmative action in the United States. The author describes the impact of the "Brown v. Board of Education" on minority life science education. She also discusses how The American Society for Cell Biology (ASCB) Minorities Affairs Committee (MAC) can improve the minority science pipeline. (Contains 1…

  2. Happy 50th, Smokey Bear! A Learning Kit about Forests and Fire Safety for Grades K-3.

    ERIC Educational Resources Information Center

    Hall, Meryl

    In 1994, Smokey Bear turns 50! For a half century, Smokey has been helping children and adults protect forests and wildlands from careless fire. With this kit students can celebrate Smokey's message using a variety of activities that include dramatic play, stories, games, and things to make and do. Through these activities, students learn about…

  3. 3 CFR 8886 - Proclamation 8886 of October 9, 2012. 50th Anniversary of the Office of the United States Trade...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... strategy for an economy built to last. On this anniversary, we recognize the dedicated professionals who... best place in the world to innovate, invest, work, and build a business. NOW, THEREFORE, I,...

  4. 3 CFR 9004 - Proclamation 9004 of August 23, 2013. 50th Anniversary of the March on Washington for Jobs and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., white, Latino, Asian, and Native American—woven together like a great American tapestry, sharing in the dream that our Nation would one day make real the promise of liberty, equality, and justice for all. The...; when one American gets a raw deal, it jeopardizes justice for everyone. These are lessons we...

  5. Quality Improvement Project to Improve Patient Satisfaction With Pain Management: Using Human-Centered Design.

    PubMed

    Trail-Mahan, Tracy; Heisler, Scott; Katica, Mary

    2016-01-01

    In this quality improvement project, our health system developed a comprehensive, patient-centered approach to improving inpatient pain management and assessed its impact on patient satisfaction across 21 medical centers. Using human-centered design principles, a bundle of 6 individual and team nursing practices was developed. Patient satisfaction with pain management, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems pain composite score, increased from the 25th to just under the 75th national percentile. PMID:26447343

  6. Contribution of dietary advanced glycation end products (AGE) to circulating AGE: role of dietary fat.

    PubMed

    Davis, Kathleen E; Prasad, Chandan; Vijayagopal, Parakat; Juma, Shanil; Adams-Huet, Beverley; Imrhan, Victorine

    2015-12-14

    The purpose of this pilot study was to determine whether macronutrient content (low-fat v. high-fat diet) influences an indicator of advanced glycation end products (AGE), N(ε) carboxymethyl-lysine (CML), in the context of a 1-d, high-AGE diet. The effect of the diets on inflammatory markers was also assessed. A total of nineteen overweight and obese adults (nine men and ten women) without known disease were recruited to participate in a crossover challenge of a high-fat, high-AGE (HFHA) and low-fat, high-AGE (LFHA) diet. In each phase patients had fasting blood drawn, followed by consumption of a high-fat or low-fat breakfast test meal, then three postprandial blood draws at 1, 2 and 3 h after consuming the test meal. After consuming high-AGE meals for the remainder of the day, participants returned the next day for a follow-up analysis. A different pattern in the 3-h post-meal CML and soluble receptor for AGE response to the two diets was observed (P=0·01 and 0·05, respectively). No change in serum CML was observed following consumption of a LFHA breakfast (535 (25th-75th percentile 451-790) to 495 (25th-75th percentile 391-682) ng/ml; P=0·36), whereas a rise in CML occurred after the HFHA breakfast (463 (25th-75th percentile 428-664) to 578 (25th-75th percentile 474-865) ng/ml; P=0·05). High sensitivity C-reactive protein and high molecular weight adiponectin were not affected by either diet. These findings suggest that dietary CML may not be as important in influencing serum CML as other dietary factors. In addition, acute exposure to dietary CML may not influence inflammation in adults without diabetes or kidney disease. This is contrary to previous findings. PMID:26392152

  7. Language as Moral Action and the Ethical Dimensions of Teaching and Texts: Reflections on the 25th Year of Teaching.

    ERIC Educational Resources Information Center

    Pezzulich, Evelyn

    In the 1970s, women's literature had not yet arrived in the high school classroom, nor in graduate studies. Only some 20 years later was attention turned to women's literature through the publication of the "Norton Anthology of Literature by Women." Contemporary works by women writers that speak powerfully to the issue of women's voicelessness are…

  8. 25th anniversary article: The evolution of electronic skin (e-skin): a brief history, design considerations, and recent progress.

    PubMed

    Hammock, Mallory L; Chortos, Alex; Tee, Benjamin C-K; Tok, Jeffrey B-H; Bao, Zhenan

    2013-11-13

    Human skin is a remarkable organ. It consists of an integrated, stretchable network of sensors that relay information about tactile and thermal stimuli to the brain, allowing us to maneuver within our environment safely and effectively. Interest in large-area networks of electronic devices inspired by human skin is motivated by the promise of creating autonomous intelligent robots and biomimetic prosthetics, among other applications. The development of electronic networks comprised of flexible, stretchable, and robust devices that are compatible with large-area implementation and integrated with multiple functionalities is a testament to the progress in developing an electronic skin (e-skin) akin to human skin. E-skins are already capable of providing augmented performance over their organic counterpart, both in superior spatial resolution and thermal sensitivity. They could be further improved through the incorporation of additional functionalities (e.g., chemical and biological sensing) and desired properties (e.g., biodegradability and self-powering). Continued rapid progress in this area is promising for the development of a fully integrated e-skin in the near future. PMID:24151185

  9. The Role of SoTL in the Academy: Upon the 25th Anniversary of Boyer's "Scholarship Reconsidered"

    ERIC Educational Resources Information Center

    Kern, Beth; Mettetal, Gwendolyn; Dixson, Marcia D.; Morgan, Robin K.

    2015-01-01

    In this essay, we explore definitions and taxonomies of the Scholarship of Teaching and Learning (SoTL) and present a model of the Dimensions of Activities Related to Teaching (DART) which provides a context for SoTL along two dimensions: public/private and systematic/informal. The four quadrants: practice of teaching, sharing about teaching,…

  10. The fiber fuse--from a curious effect to a critical issue: a 25th year retrospective.

    PubMed

    Kashyap, Raman

    2013-03-11

    A process leading to a stunningly beautiful and distinctive propagating plasma emission in optical fibers was discovered by the author 25 years ago. The genie that escaped its glass bottle leaves a trail of destruction. This paper traces the history and impact of the effect, which can threaten the security of all modern communication systems. PMID:23482212

  11. 1988 IEEE Annual Conference on Nuclear and Space Radiation Effects, 25th, Portland, OR, July 12-15, 1988, Proceedings

    NASA Technical Reports Server (NTRS)

    Coakley, Peter G. (Editor)

    1988-01-01

    The effects of nuclear and space radiation on the performance of electronic devices are discussed in reviews and reports of recent investigations. Topics addressed include the basic mechanisms of radiation effects, dosimetry and energy-dependent effects, sensors in and for radiation environments, EMP/SGEMP/IEMP phenomena, radiation effects on isolation technologies, and spacecraft charging and space radiation effects. Consideration is given to device radiation effects and hardening, hardness assurance and testing techniques, IC radiation effects and hardening, and single-event phenomena.

  12. Serving Individuals Who Are Low-Functioning Deaf. Report from the Study Group, 25th Institute on Rehabilitation Issues, 1999.

    ERIC Educational Resources Information Center

    Dew, Donald W., Ed.

    This report is the outcome of study group that investigated best practices for serving individuals who are deaf and low functioning. It is designed to help State Vocational Rehabilitation (VR) Agencies assist individuals with disabilities in securing competitive employment and is meant to be a source for innovative ideas for program development…

  13. MINUTES OF THE ANNUAL CONVENTION OF THE PENNSYLVANIA ASSOCIATION OF JUNIOR COLLEGES (25TH, PITTSBURGH, OCTOBER 13-14, 1967).

    ERIC Educational Resources Information Center

    Pennsylvania Association of Junior Colleges, Altoona.

    THE KEYNOTE ADDRESS OF THIS CONVENTION DEALT WITH THE PROBLEM OF CURRICULAR OBSOLESCENCE AND HOW TO AVOID IT BY KEEPING THE PROGRAMS RELEVANT, ADVENTUROUS, ADAPTABLE, AND FLEXIBLE. THERE THEN FOLLOWED WORKSHOPS OR DISCUSSION GROUPS ON THE FOLLOWING TOPICS--(1) MODERN METHODS OF TEACHING ENGLISH, (2) SOCIAL SCIENCE (FACTORS OF OBSOLESCENCE AND…

  14. The Anesthesia Patient Safety Foundation at 25: a pioneering success in safety, 25th anniversary provokes reflection, anticipation.

    PubMed

    Eichhorn, John H

    2012-04-01

    The Anesthesia Patient Safety Foundation (APSF) was created in 1985. Its founders coined the term "patient safety" in its modern public usage and created the very first patient safety organization, igniting a movement that is now universal in all of health care. Driven by the vision "that no patient shall be harmed by anesthesia," the APSF has worked tirelessly for more than a quarter century to promote safety education and communication through its widely read Newsletter, its programs, and its presentations. The APSF's extensive research grant program has supported a great many projects leading to key safety improvements and, in particular, was central in the development of high-fidelity mannequin simulation as a research and teaching tool. With its pioneering collaboration, the APSF is unique in incorporating the talents and resources of anesthesia professionals of all types, safety scientists, pharmaceutical and equipment manufacturers, regulators, liability insurance companies, and also surgeons. Specific alerts, campaigns, discussions, and projects have targeted a host of safety issues and dangers over the years, starting with minimal intraoperative monitoring in 1986 and all the way up to beach-chair position cerebral perfusion pressure, operating room medication errors, and the extremely popular DVD on operating room fire safety in 2010; the list is long and expansive. The APSF has served as a model and inspiration for subsequent patient safety organizations and has been recognized nationally as having a dramatic positive impact on the safety of anesthesia care. Recognizing that the work is not over, that systems, organizations, and equipment still at times fail, that basic preventable human errors still do sometimes occur, and that "production pressure" in anesthesia practice threatens past safety gains, the APSF is firmly committed and continues to work hard both on established tenets and new patient safety principles. PMID:22253277

  15. Biotechnology and the Third World: Panacea or Recipe for Social Disaster? Academy for Educational Development 25th Anniversary Series.

    ERIC Educational Resources Information Center

    Morehouse, Ward

    Asserting that developmental growth is easier to attain in developing countries than social change, this paper assesses the prospective impact of biotechnology on the developing nations. Biotechnology is defined as the integrated use of biochemistry, microbiology, and chemical engineering to achieve the industrial processes of fermentation, enzyme…

  16. Proceedings of the Invitational Conference on Testing Problems (25th, New York, New York, October 31, 1964).

    ERIC Educational Resources Information Center

    Educational Testing Service, Princeton, NJ.

    This conference focuses upon various aspects of testing within a society, and upon technical advances in measurement. Philip H. DuBois's paper deals with China, a society dominated by tests, from 1115 BC--1905 AD. Donald W. Fiske discusses the effect of testing on the individual in modern America in his paper, "The Subject Looks at Psychological…

  17. Highlights of the International Symposium on Plant Lipids, 18th ISPL 2008, Bordeaux July 20–25th, 2008

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Plant lipids are of considerable interest in economic sectors such as agriculture, food, health and the cosmetics industry. In addition, the sector of renewable energies is showing increasing interest in the field of plant lipids. Our society is highly dependent on raw fossil materials whose reserve...

  18. Education, Section J. Extracted from the 2000 New York State Statistical Yearbook. 25th Anniversary Edition. Revised and Expanded.

    ERIC Educational Resources Information Center

    State Univ. of New York, Albany. Nelson A. Rockefeller Inst. of Government.

    This yearbook presents statistical information about the state of New York and its population as well as information on the five boroughs of New York City. The 41 tables of Section J describe education in New York state in the 1990s and into 2000 and contain information that makes it possible to compare these statistics from previous years and for…

  19. A resolution celebrating February 2, 2011, as the 25th anniversary of "National Women and Girls in Sports Day".

    THOMAS, 112th Congress

    Sen. Snowe, Olympia J. [R-ME

    2011-01-27

    02/02/2011 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S492) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  20. 25th anniversary article: Design of polymethine dyes for all-optical switching applications: guidance from theoretical and computational studies.

    PubMed

    Gieseking, Rebecca L; Mukhopadhyay, Sukrit; Risko, Chad; Marder, Seth R; Brédas, Jean-Luc

    2014-01-01

    All-optical switching--controlling light with light--has the potential to meet the ever-increasing demand for data transmission bandwidth. The development of organic π-conjugated molecular materials with the requisite properties for all-optical switching applications has long proven to be a significant challenge. However, recent advances demonstrate that polymethine dyes have the potential to meet the necessary requirements. In this review, we explore the theoretical underpinnings that guide the design of π-conjugated materials for all-optical switching applications. We underline, from a computational chemistry standpoint, the relationships among chemical structure, electronic structure, and optical properties that make polymethines such promising materials. PMID:24302357

  1. Heat Transfer and Fluid Mechanics Institute, Meeting, 25th, University of California, Davis, Calif., June 21-23, 1976, Proceedings

    NASA Technical Reports Server (NTRS)

    Mckillop, A. A.; Baughn, J. W.; Dwyer, H. A.

    1976-01-01

    Major research advances in heat transfer and fluid dynamics are outlined, with particular reference to relevant energy problems. Of significant importance are such topics as synthetic fuels in combustion, turbulence models, combustion modeling, numerical methods for interacting boundary layers, and light-scattering diagnostics for gases. The discussion covers thermal convection, two-phase flow and boiling heat transfer, turbulent flows, combustion, and aerospace heat transfer problems. Other areas discussed include compressible flows, fluid mechanics and drag, and heat exchangers. Featured topics comprise heat and salt transfer in double-diffusive systems, limits of boiling heat transfer in a liquid-filled enclosure, investigation of buoyancy-induced flow stratification in a cylindrical plenum, and digital algorithms for dynamic analysis of a heat exchanger. Individual items are announced in this issue.

  2. 77 FR 76411 - Security Zone; 25th Annual North American International Auto Show, Detroit River, Detroit, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal Register NPRM Notice of Proposed... temporary final rule, call or email LT Adrian Palomeque, Prevention Department, Sector Detroit, Coast Guard; telephone (313) 568-9508, email Adrian.F.Palomeque@uscg.mil . If you have questions on viewing the...

  3. [Dr. Piotr Borsukiewicz--one of the pleiad of physicians in Lublin (the 75th anniversary of his death)].

    PubMed

    Staszyc, J

    1992-01-01

    Seventy years have passed since the death of dr Piotr Borsukiewicz. He spent 9 out of his 22 years of work in Lublin (1909-1918) being the head of the paediatric hospital (1911-1918), the member of the Lublin Medical Society, the president and vice president of some other public service organizations and inscribed himself in letters of gold in the history of medicine and people of Lublin. He worked and lived in the difficult years of two wars (1904-1905 and 1914-1918), the rapid development of medical sciences and the separation of medical specialties. His diligence, loyalty to the Hippocratic code and the instructions of dr W. Biegański as well as to the patriotic dictates resulted in the union of the meaning of his own existence with the deep belief in man and the favourite work as a physician. Helping the poor and those in need he contracted spotted fever but belittled his complaints and died on April 12, 1918 in Lublin. He left us the special patterns of the ideal medical care which are still alive today, so non omnis moriar. PMID:1365791

  4. 3 CFR 8546 - Proclamation 8546 of August 13, 2010. 75th Anniversary of the Social Security Act

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the United States of America A Proclamation On August 14, 1935, President Franklin D. Roosevelt signed... poverty-ridden old age.” Our Nation was entrenched in the Great Depression. Unemployment neared 20 percent... will not live in poverty. My Administration is committed to strengthening our retirement system...

  5. In Diversity Is Strength: Capitalizing on the New Work Force. 75th Anniversary Symposia Series. Report Number 994.

    ERIC Educational Resources Information Center

    Alster, Judith, Ed.; And Others

    This document, which is based on a symposium devoted to capitalizing on the new work force, contains five reports describing how major U.S. corporations are dealing with the demographic changes currently under way in the United States. "Whither the Work Force?" (Delores Wolf) discusses the proper role of corporations in coping with a lack of…

  6. Fifty years of IMOG (International Meetings on Organic Geochemistry)

    USGS Publications Warehouse

    Kvenvolden, Keith A.

    2012-01-01

    IMOG2011 is the 25th of a series of international meetings on organic geochemistry that began in 1962. Thus, this 25th meeting marks the 50th anniversary year of IMOG, which has (a) had a rich history with meetings taking place in 11 different countries, (b) published Proceedings, titled “Advances in Organic Geochemistry,” from each meeting that now number 24 volumes totaling almost 18,000 pages, and (c) documented the content and development of the science of organic geochemistry. IMOG2011 adds a new milestone to the progress of organic geochemistry through time.

  7. Hepcidin and Risk for Anemia in CKD: A Cross-sectional and Longitudinal Analysis in the CKiD Cohort

    PubMed Central

    Atkinson, Meredith A.; Kim, Ji Young; Roy, Cindy N.; Warady, Bradley A.; White, Colin T.; Furth, Susan L.

    2014-01-01

    Background Hepcidin, a key iron regulatory protein, is elevated in patients with chronic kidney disease (CKD). Its role in the development and progression of the anemia of CKD in children remains poorly defined. Methods Cross-sectional and longitudinal study in children aged 1–16 years with stage 2–4 CKD in the Chronic Kidney Disease in Children (CKiD) cohort (n=133) with hepcidin measured at baseline and hemoglobin (HGB) measured annually in follow-up. Anemia was defined as HGB < 5th percentile for age/sex OR treatment with an erythropoiesis stimulating agent (ESA). Results Hepcidin levels correlated negatively with glomerular filtration rate (GFR) (r=−0.22, p=0.01) and positively with ferritin (r=0.67, p<0.001). At the lower end of the GFR spectrum at baseline (10th percentile, 27.5 ml/min/1.73m2), higher hepcidin was associated with a 0.87 g/dL decrease in HGB during follow-up (95% CI −1.69, −0.05 g/dL, p=0.038). At higher GFR percentiles there was no significant association between baseline hepcidin and HGB during follow-up. Among 90 non-anemic subjects at baseline, 23.3% developed incident anemia. In subjects with GFR ≤ the median, a higher hepcidin level was associated with an increased risk for incident anemia (at 10th %ile GFR, HR 3.471, 95% CI 1.228, 9.810, p=0.019; at 25th %ile GFR HR 2.641, 95% CI 1.213, 5.750, p=0.014; at 50th %ile GFR, HR 1.953, 95% CI 1.011, 3.772, p=0.046). Among subjects with GFR in the 75th percentile or above, incrementally higher baseline hepcidin was not associated with increased anemia risk. Conclusions Higher hepcidin levels are associated with a decreased HGB and an increased risk for incident anemia, and this association is most significant among subjects with lower GFR. PMID:25380788

  8. Computed tomography-defined abdominal adiposity is associated with acute kidney injury in critically ill trauma patients

    PubMed Central

    Shashaty, Michael G. S.; Kalkan, Esra; Bellamy, Scarlett L.; Reilly, John P.; Holena, Daniel N.; Cummins, Kathleen; Lanken, Paul N.; Feldman, Harold I.; Reilly, Muredach P.; Udupa, Jayaram K.; Christie, Jason D.

    2014-01-01

    Objective Higher body mass index (BMI) is associated with increased risk of acute kidney injury (AKI) after major trauma. Since BMI is non-specific, reflecting lean, fluid, and adipose mass, we evaluated the use of computed tomography (CT) to determine if abdominal adiposity underlies the BMI-AKI association. Design Prospective cohort study. Setting Level I Trauma Center of a university hospital. Patients Patients older than 13 years with an Injury Severity Score ≥16 admitted to the trauma intensive care unit were followed for development of AKI over five days. Those with isolated severe head injury or on chronic dialysis were excluded. Interventions None Measurements and Main Results Clinical, anthropometric, and demographic variables were collected prospectively. CT images at the level of the L4-5 intervertebral disc space were extracted from the medical record and used by two operators to quantitate visceral and subcutaneous adipose tissue (VAT and SAT, respectively) areas. AKI was defined by Acute Kidney Injury Network (AKIN) creatinine and dialysis criteria. Of 400 subjects, 327 (81.8%) had CT scans suitable for analysis: 264/285 (92.6%) blunt trauma subjects, 63/115 (54.8%) penetrating trauma subjects. VAT and SAT areas were highly correlated between operators (ICC>0.999, p<0.001 for each) and within operator (ICC>0.999, p<0.001 for each). In multivariable analysis, the standardized risk of AKI was 15.1% (95% CI 10.6%,19.6%), 18.1% (14%,22.2%), and 23.1% (18.3%,27.9%) at the 25th, 50th, and 75th percentiles of VAT area, respectively (p=0.001), with similar findings when using SAT area as the adiposity measure. Conclusions Quantitation of abdominal adiposity using CT scans obtained for clinical reasons is feasible and highly reliable in critically ill trauma patients. Abdominal adiposity is independently associated with AKI in this population, confirming that excess adipose tissue contributes to the BMI-AKI association. Further studies of the potential

  9. Prenatal Exposure to Cadmium, Placental Permeability and Birth Outcomes in Coastal Populations of South Africa

    PubMed Central

    Röllin, Halina B.; Kootbodien, Tahira; Channa, Kalavati; Odland, Jon Ø.

    2015-01-01

    Background The impact of prenatal exposure to cadmium (Cd) on birth outcomes is an area of concern. This study aimed to assess an impact of prenatal Cd exposure on birth outcomes in distinct coastal populations of South Africa. Methods Cadmium was measured in maternal blood (CdB) (n = 641), cord blood and in maternal urine (n = 317). This investigation assessed the associations between CdB (non-transformed) and birth outcomes across the 25th, 50th, and 75th percentile for birth weight, birth length and head circumference, to test for a linear trend. Associations between natural log-transformed maternal CdB, size at birth and other factors were further evaluated using linear mixed-effects modelling with random intercepts. Results The average gestational age in the total sample was 38 weeks; 47% of neonates were female, average birth weight was 3065 g and 11% were of low birth weight (< 2500 g). The geometric mean (GM) of the maternal CdB level was 0.25 μg/L (n = 641; 95% CI, 0.23–0.27). The cord blood Cd level was 0.27 μg/L (n = 317; 95% CI, 0.26–0.29) and urine (creatinine-corrected) Cd level was 0.27 μg/L (n = 318; 95% CI, 0.24–0.29). The CdB cord:maternal ratio in the sub-cohort was 1, suggesting that the placenta offers no protective mechanism to the foetus. An inverse association was found between CdB and the lower birth weight percentile in female neonates only (β = - 0.13, p = 0.047). Mothers who reported eating vine vegetables daily had lower levels of CdB (β = - 0.55, p = 0.025). Maternal smoking was associated with an elevation in natural log-transformed CdB levels in both male and female cohorts. Discussion Significant inverse associations between prenatal Cd exposure and birth anthropometry were found in female neonates but not in male neonates, suggesting potential sex differences in the toxico-kinetics and toxico-dynamics of Cd. PMID:26544567

  10. Update of Watershed Regressions for Pesticides (WARP) for Predicting Atrazine Concentration in Streams

    USGS Publications Warehouse

    Stone, Wesley W.; Gilliom, Robert J.

    2009-01-01

    Regression models for predicting atrazine concentrations in streams were updated by incorporating refined annual atrazine-use estimates and by adding an explanatory variable representing annual precipitation characteristics. The updated Watershed Regressions for Pesticides (WARP) models enable improved predictions of specific pesticide-concentration statistics for unmonitored streams. for unmonitored streams. Separate WARP regression models were derived for selected percentiles (5th, 10th, 15th, 25th, 50th, 75th, 85th, 90th and 95th), annual mean, annual maximum, and annual maximum moving-average (21-, 60-, and 90-day durations) concentration statistics. Development of the regression models involved the same model-development data, model-validation data, and regression methods as those used in the original development of WARP. The original WARP models were based on atrazine-use estimates from either 1992 or 1997. This update of the WARP models incorporates annual atrazine-use estimates. In addition, annual precipitation data were evaluated as potential explanatory variables. as potential explanatory variables. The updated WARP models include the same five explanatory variables and transformations that were used in the original WARP models, including the new annual atrazine-use data. The models also include a sixth explanatory variable, total precipitation during May and June of the year of sampling. The updated WARP models account for as much as 82 percent of the variability in the concentration statistics among the 112 sites used for model development, whereas previous WARP models accounted for no more than 77 percent. Concentration statistics predicted by the 95th percentile, annual mean, annual maximum and annual maximum moving-average concentration models were within a factor of 10 of the observed concentration statistics for most of the model development and validation sites. Overall, performance of the models for the development and validation sites supports

  11. BMI, Waist Circumference Reference Values for Chinese School-Aged Children and Adolescents

    PubMed Central

    Song, Peige; Li, Xue; Gasevic, Danijela; Flores, Ana Borges; Yu, Zengli

    2016-01-01

    Background: Childhood obesity has become one of the most serious public health challenges in the 21st century in most developing countries. The percentile curve tool is useful for monitoring and screening obesity at population level, however, in China, no official recommendations on childhood body mass index (BMI) and waist circumference (WC) reference percentiles have been made in practice. Aims: to construct the percentile reference values for BMI and WC, and then to calculate the prevalence of overall and abdominal obesity for Chinese children and adolescents. Methods: A total of 5062 anthropometric records for children and adolescents aged from 7 to 18 years (2679 boys and 2383 girls) were included for analysis. The participants were recruited as part of the national representative “China Health and Nutrition Survey” (CHNS). Age, gender, weight, height, and WC were assessed. Smoothed BMI and WC percentile curves and values for the 3rd, 5th, 10th, 15th, 25th, 50th, 75th, 85th, 90th, 95th and 97th percentiles were constructed by using the Lambda-Mu-Sigma (LMS) method. The prevalence estimates of the overall and abdominal obesity were calculated by using the cut-offs from our CHNS study and the previous “Chinese National Survey on Students’ Constitution and Health” (CNSSCH) study, respectively. The difference between prevalence estimates was tested by a McNemar test, and the agreement between these prevalence estimates was calculated by using the Cohen’s kappa coefficient. Results: The prevalence values of overall obesity based on the cut-offs from CHNS and CNSSCH studies were at an almost perfect agreement level in boys (κ = 0.93). However, among girls, the overall obesity prevalence differed between the studies (p < 0.001) and the agreement was weaker (κ = 0.76). The abdominal obesity prevalence estimates were significant different according to the two systems both in boys and girls, although the agreement reached to 0.88, which represented an

  12. Statistical analysis and mapping of water levels in the Biscayne aquifer, water conservation areas, and Everglades National Park, Miami-Dade County, Florida, 2000–2009

    USGS Publications Warehouse

    Prinos, Scott T.; Dixon, Joann F.

    2016-01-01

    Maps were created by importing site coordinates, summary water-level statistics, and completeness of record statistics into a geographic information system, and by interpolating between water levels at monitoring sites in the canals and water levels along the coastline. Raster surfaces were created from these data by using the triangular irregular network interpolation method. The raster surfaces were contoured by using geographic information system software. These contours were imprecise in some areas because the software could not fully evaluate the hydrology given available information; therefore, contours were manually modified where necessary. The ability to evaluate differences in water levels between 1990–1999 and 2000–2009 is limited in some areas because most of the monitoring sites did not have 80 percent complete records for one or both of these periods. The quality of the analyses was limited by (1) deficiencies in spatial coverage; (2) the combination of pre- and post-construction water levels in areas where canals, levees, retention basins, detention basins, or water-control structures were installed or removed; (3) an inability to address the potential effects of the vertical hydraulic head gradient on water levels in wells of different depths; and (4) an inability to correct for the differences between daily water-level statistics. Contours are dashed in areas where the locations of contours have been approximated because of the uncertainty caused by these limitations. Although the ability of the maps to depict differences in water levels between 1990–1999 and 2000–2009 was limited by missing data, results indicate that near the coast water levels were generally higher in May during 2000–2009 than during 1990–1999; and that inland water levels were generally lower during 2000–2009 than during 1990–1999. Generally, the 25th, 50th, and 75th percentiles of water levels from all months were also higher near the coast and lower inland

  13. Vigorous exercise and the population distribution of bodyweight

    SciTech Connect

    Williams, Paul T.

    2002-09-18

    Background: While the benefits of vigorous exercise on body weight and regional adiposity are well established, whether these benefits affect equally the highest and lowest portions of the weight distribution has not been previously reported. The impact of exercise on the more extreme body weights and body circumferences is clinically important because these values represent individuals at greatest health risk. Method: We divided self-reported weights and body circumferences from a cross-sectional sample of 7,288 male and 2,359 female runners into five strata according to the distances run per week and within each stratum determined the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles. Then Least-squares regression was then employed at each percentile to determine the dose-response relationship between running distance and adiposity. Results: Per kilometer run per week, the associated decline for body mass index (BMI) was three-fold greater at the 95th than at the 5th percentile in men, and nine-fold greater at the 95th than the 5th percentile in women (all P<0.001). Reported waist circumference also declined more sharply at the 95th percentile than at the 5th percentile in men (-0.13/261 0.02 versus -0.06 plus or minus 0.01 cm per km/wk) and women (-0.18 plus or minus 0.04 versus -0.05 plusor minus 0.01 cm per km/wk). In women, both hip and chest circumferences declined more sharply per kilometer run at the 95th percentile than at the 5th percentile. Conclusions: These results support the hypothesis that running promotes the greatest weight loss specifically in those individuals who have the most to gain from losing weight. Comparisons based on average BMI or average body circumferences are likely to underestimate the health benefits of running because of the J-shaped relationship between adiposity and mortality. Whether the observed associations are primarily due to exercise-induced weight loss or self-selection remains to be determined.

  14. Gestational weight gain standards based on women enrolled in the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project: a prospective longitudinal cohort study

    PubMed Central

    Bishop, Deborah C; Pang, Ruyan; Ohuma, Eric O; Kac, Gilberto; Abrams, Barbara; Rasmussen, Kathleen; Barros, Fernando C; Hirst, Jane E; Lambert, Ann; Papageorghiou, Aris T; Stones, William; Jaffer, Yasmin A; Altman, Douglas G; Noble, J Alison; Giolito, Maria Rosa; Gravett, Michael G; Purwar, Manorama; Kennedy, Stephen H; Bhutta, Zulfiqar A; Villar, José

    2016-01-01

    Objective To describe patterns in maternal gestational weight gain (GWG) in healthy pregnancies with good maternal and perinatal outcomes. Design Prospective longitudinal observational study. Setting Eight geographically diverse urban regions in Brazil, China, India, Italy, Kenya, Oman, United Kingdom, and United States, April 2009 to March 2014. Participants Healthy, well nourished, and educated women enrolled in the Fetal Growth Longitudinal Study component of the INTERGROWTH-21st Project, who had a body mass index (BMI) of 18.50-24.99 in the first trimester of pregnancy. Main outcome measures Maternal weight measured with standardised methods and identical equipment every five weeks (plus/minus one week) from the first antenatal visit (<14 weeks’ gestation) to delivery. After confirmation that data from the study sites could be pooled, a multilevel, linear regression analysis accounting for repeated measures, adjusted for gestational age, was applied to produce the GWG values. Results 13 108 pregnant women at <14 weeks’ gestation were screened, and 4607 met the eligibility criteria, provided consent, and were enrolled. The variance within sites (59.6%) was six times higher than the variance between sites (9.6%). The mean GWGs were 1.64 kg, 2.86 kg, 2.86 kg, 2.59 kg, and 2.56 kg for the gestational age windows 14-18+6 weeks, 19-23+6 weeks, 24-28+6 weeks, 29-33+6 weeks, and 34-40+0 weeks, respectively. Total mean weight gain at 40 weeks’ gestation was 13.7 (SD 4.5) kg for 3097 eligible women with a normal BMI in the first trimester. Of all the weight measurements, 71.7% (10 639/14 846) and 94.9% (14 085/14 846) fell within the expected 1 SD and 2 SD thresholds, respectively. Data were used to determine fitted 3rd, 10th, 25th, 50th, 75th, 90th, and 97th smoothed GWG centiles by exact week of gestation, with equations for the mean and standard deviation to calculate any desired centiles according to gestational age in exact weeks. Conclusions

  15. A review of stream nutrient criteria development in the United States.

    PubMed

    Evans-White, M A; Haggard, B E; Scott, J T

    2013-07-01

    Elevated nutrients and sediments are the main factors contributing to the poor biological condition measured in over 40% of US waters, highlighting the need for criteria that can aid management efforts to protect or restore the quality of US waters. A large amount of literature on nutrient criteria has been generated since the USEPA called for their development in 1998. Our objective was to examine this peer-reviewed literature to evaluate two main approaches for criteria development in lotic ecosystems: percentile rank and bivariate predictive statistical analyses. The 25th percentile approach has been examined broadly across USEPA-aggregate nutrient ecoregions, and we found that USEPA-suggested criteria for these aggregate ecoregions were often more conservative than criteria estimated using more current regionally focused data based on our compiled data set. Furthermore, 25th percentile estimates were often less than 75th percentile estimates based on reference sites, suggesting that 75th percentile estimates were not more conservative than 25th percentile estimates. Predictive approaches have focused on establishing linear and nonlinear relationships between water quality and algae, macroinvertebrate, and fish communities; attributing causation; and determining whether threshold points exist that can aid in nutrient criteria development. Most of the predictive approaches have occurred at the state or watershed level and may not be directly comparable to USEPA aggregate ecoregions. However, percentile method estimates often fell within the confidence interval of biological threshold criteria estimates, suggesting overlap and some consensus between the two main approaches. PMID:24216352

  16. Let's Make the Next Generation Tobacco-Free: Your Guide to the 50th Anniversary Surgeon General's Report on Smoking and ...

    MedlinePlus

    ... or blocked arteries in and around the heart (coronary heart disease), high blood pressure (hypertension), heart attack (acute myocardial ... die every year in the United States from coronary heart disease caused by exposure to secondhand smoke. Peripheral Ar ...

  17. Symposium on the 50th anniversary of the discovery of deuterium: divisions of history of chemistry, geochemistry, nuclear and physical chemistry

    SciTech Connect

    Bigeleisen, J.

    1981-01-01

    In tribute to Harold Urey, the author cites Urey's accomplishments as a scientist and public servant and gives insight of the man. Some of his accomplishments in science are: discovered deuterium for which he received the Nobel prize in 1934; worked with Rittenberg and Greiff on the theory and calculation of the differences in the thermodynamic properties of isotopic compounds; with Thode, Hutchison and others, separated the isotopes of the light elements by chemical methods on a laboratory scale; during World War II headed the Substitute Alloy Materials Laboratories of Columbia University where his group developed industrial scale processes for the separation of /sup 2/H, /sup 10/B, and /sup 235/U; with his associates developed the /sup 18/O paleotemperature scale; made fundamental contributions to a widely accepted theory of the origin of the earth. (ATT)

  18. Milk and dairy products in the 21st century. Prepared for the 50th anniversary of the journal of agricultural and food chemistry.

    PubMed

    Creamer, Lawrence K; Pearce, Lindsay E; Hill, Jeremy P; Boland, Mike J

    2002-12-01

    Dairying into the 21st century will largely continue with the trends seen in the past few decades, although there is always the possibility of an unlikely but disruptive event. The politics of globalization will potentially be important in freeing up global trade in dairy products. Production on the farm will become increasingly efficient, resulting in continuing price benefits to the consumer. At the same time, increasing attention will be paid by the consumer, producer, and manufacturer to safety and quality issues. Environmental concerns will increase in importance, and the issue of methane production may be important for the industry over the next two decades. It is unlikely that genetically modified milk will be introduced soon, even if public acceptance ceases to be an issue; however, the use of genetic markers for accelerated genetic improvement of cows will have rapidly increasing importance. Despite increasing pressure from nonmilk alternatives, milk and dairy will still be the best sources of nutrition for the young and for traditional dairy products. Consumer concerns will be of overriding importance for the industry, and the safety of dairy foods must become absolute. Recent advances in the chemical, physical, and information sciences and technologies will be utilized to gain greater understanding of the increasingly complex food systems and to support the consumer objectives. PMID:12452630

  19. A resolution recognizing the 50th anniversary of the Congressional declaration of bourbon whiskey as a distinctive product of the United States.

    THOMAS, 113th Congress

    Sen. McConnell, Mitch [R-KY

    2014-05-15

    05/15/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S3049-3050; text as passed Senate: CR S3078) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  20. A resolution commemorating the 50th anniversary of the founding of the Organization of African Unity (OAU) and commending its successor, the African Union.

    THOMAS, 113th Congress

    Sen. Coons, Christopher A. [D-DE

    2013-06-10

    06/26/2013 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (consideration: CR S5304-5305) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  1. Commemorating the 50th anniversary of the founding of the Organization of African Unity (OAU) and commending its successor, the African Union.

    THOMAS, 113th Congress

    Rep. Bass, Karen [D-CA-37

    2013-05-23

    06/07/2013 Referred to the Subcommittee on Africa, Global Health, Global Human Rights and International Organizations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  2. Vacation Study Abroad 2000/2001: 50th Anniversary Edition of IIE's Complete Guide to Summer and Short-Term Study.

    ERIC Educational Resources Information Center

    Steen, Sara J., Ed.

    This guide provides descriptions of 2,239 summer and short-term study-abroad opportunities that range in length from one week to several months. Introductory material provides information on the Institute of International Education (IIE), IIE publications, how to use the guide, abbreviations, planning for study abroad, additional resources for…

  3. A resolution commemorating the 50th anniversary of the Bay of Pigs operation and commending the members of Brigada de Asalto 2506 (Assault Brigade 2506).

    THOMAS, 112th Congress

    Sen. Rubio, Marco [R-FL

    2011-04-12

    04/12/2011 Referred to the Committee on Foreign Relations. (text of measure as introduced: CR S2398) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. Comments on the Classic Henry and Rogers (1960) Paper on Its 50th Anniversary: Resolving the Issue of Simple versus Choice Reaction Time

    ERIC Educational Resources Information Center

    Klapp, Stuart T.

    2010-01-01

    The effect of response complexity on simple RT, first reported by Henry and Rogers (H&R), is a robust phenomenon for complexity measured by the number of chunks in a multiple-chunk response. However, there are problems with the memory drum theory H&R used to account for this result, and no fully satisfactory alternative explanation has been…

  5. S.Res.614 — 111th Congress (2009-2010) A resolution commemorating the 50th anniversary of the publication of "To Kill a Mockingbird".

    THOMAS, 111th Congress

    Sen. Sessions, Jeff [R-AL

    2010-08-05

    08/05/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6981; text as passed Senate: CR S6981; text of measure as introduced: CR S6908) (All Actions)

  6. [Polish School of Medicine at the University of Edinburgh, in the years of World War II. (50th anniversary of closure)].

    PubMed

    Imieliński, B L

    1999-01-01

    Half a century ago the activity of the Polish School of Medicine at the University of Edinburgh came to an end. It seems a good occasion to recall its beginnings and recognise its merits for Poland and for medical education. The school was a Scottish-Polish academic enterprise, unique in the history of universities, presenting an example of international academic co-operation. It was then the only legal Polish medical school in the years of World War II. The founders of it were: Lt.Col. Professor Francis A. E. Crew, Commanding Officer of the Military Hospital at Edinburgh Castle, who conceived the idea of a Polish medical school as a part of the University of Edinburgh, the Dean of the Medical Faculty, Professor Sidney Smith, who along with Sir Thomas Holland, the Principal of the University put the idea into motion through the University authorities on the Scottish side-and the Commander in Chief of the Polish Forces and Prime Minister General Władysław Sikorski, who gave his whole-hearted support and Lt.Col. Dr Antoni Jurasz, Professor of Surgery at the University of Poznań, who became the main organiser and first dean of the Faculty-on the Polish side. It was an independent Polish academic institution being simultaneously an integral part of the University. The medical training underwent 337 undergraduates, 227 out of whom obtained the degree M.B.Ch.B. and 19 degrees of Ph.D. after submission of doctoral thesis. The majority of them had served in the Polish troops being referred by the Military authorities and many of them took later part in the war campaigns. Much emphasis is put on the activity of Wiktor Tomaszewski, Associate Professor of medicine, ex-Senior Lecturer of the School, explorer of historical bounds between two nations, and above all, the organiser of the anniversary celebrations, so much animated by a passion for unceasing memory of the school. He was honored by granting F.R.C.P. (Ed.) and honorary doctorship of the University. PMID:14631981

  7. A resolution recognizing the 50th anniversary of the historic achievement of John Herschel Glenn, Jr., in becoming the first United States astronaut to orbit the Earth.

    THOMAS, 112th Congress

    Sen. Brown, Sherrod [D-OH

    2012-02-15

    02/15/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S690-692; text as passed Senate: CR S690-691; text of measure as introduced: CR S703-704) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  8. A resolution to observe the contributions of the American Chiropractic Association and to recognize the 50th anniversary of the founding of the organization.

    THOMAS, 113th Congress

    Sen. Harkin, Tom [D-IA

    2013-03-07

    03/07/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S1274; text as passed Senate: CR S1273) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  9. Some results of the growth of semiconductor crystals in microgravity conditions (to the 50th anniversary of Yuri Gagarin's flight into space)

    NASA Astrophysics Data System (ADS)

    Shul'pina, I. L.; Zakharov, B. G.; Parfen'ev, R. V.; Farbshtein, I. I.; Serebryakov, Yu. A.; Prokhorov, I. A.

    2012-07-01

    The history of the growth of semiconductor crystals aboard space vehicles and their subsequent investigation has been described shortly. It has been shown using Ge(Ga), GaSb(Si), and GaSb(Te) crystals as an example that the formation of segregation growth striations can be avoided during their recrystallization by the vertical Bridgman method in conditions of physical simulation of microgravity on the Earth, mainly due to the essential weakening of the thermal gravitation convection. By their structure and impurity distribution, they approach the crystals grown in space. The investigation of recrystallization of Te has made it possible to determine the role of the detachment effect characteristic of the microgravity conditions and the features of the microstructure of the samples that crystallize with a free surface. The analysis of the results obtained from experiments in space allows us to better understand the processes occurring during the crystallization of the melts and to improve the crystal growth in terrestrial conditions.

  10. SHAPING the Future: Our Cause, 50 Million Strong. National Association of Kinesiology in Higher Education 50th Amy Morris Homans Commemorative Lecture 2016

    ERIC Educational Resources Information Center

    Lambdin, Dolly

    2016-01-01

    Amy Morris Homans was an amazing leader in the early development of physical education. She believed that every individual must be educated academically and physically. Earlier this year, SHAPE America committed to making her vision a reality with the goal of empowering ALL students with the skills, knowledge, habits, and determination to make…

  11. Nutrient and chlorophyll relations in selected streams of the New England Coastal Basins in Massachusetts and New Hampshire, June-September 2001

    USGS Publications Warehouse

    Riskin, Melissa L.; Deacon, J.R.; Liebman, M.L.; Robinson, K.W.

    2003-01-01

    study exceeded the preliminary U.S. Environmental Protection Agency nutrient criteria values for the coastal region of New England. In an effort to establish more appropriate nutrient and chlorophyll criteria for streams in the New England coastal region, relations between total nitrogen and total phosphorus to periphyton chlorophyll a in wadeable streams from this study were quantified to present potential techniques for determining nutrient concentrations. Linear regression was used to estimate the total nitrogen and total phosphorus concentrations that corresponded to various chlorophyll a concentrations. On the basis of this relation, a median concentration for moderately enriched streams of 21 milligrams per square meter (mg/m2) of periphyton chlorophyll a from the literature corresponded to estimated concentrations of 1.3 milligrams per liter (mg/L) for total nitrogen and 0.12 mg/L for total phosphorus. The median concentration for periphyton chlorophyll a from the literature is similar to the 50th-percentile concentration of periphyton chlorophyll a (17 mg/m2) calculated with the data from open-canopy sites in this study. The 25th-percentile concentration for periphyton chlorophyll a of all open-canopy sites (5.2 mg/m2) and the 75th-percentile concentration for periphyton chlorophyll a of open-canopy reference sites (16 mg/m2) also were plotted to provide additional estimates and methods for developing total nitrogen and total phosphorus criteria. The 25th-percentile concentrations of total nitrogen and total phosphorus were calculated based on all sites in this study and were used as another potential criteria estimation. A concentration of 0.64 mg/L for total nitrogen and 0.030 mg/L for total phosphorus were calculated. As another possible method to develop threshold concentrations, the 10th-percentile concentrations of total nitrogen and total phosphorus were calculated based on all the impaired sites in this study. A concentration threshold of 0

  12. An analysis of potential water availability from the Charles Mill, Clendening, Piedmont, Pleasant Hill, Senecaville, and Wills Creek Lakes in the Muskingum River Watershed, Ohio

    USGS Publications Warehouse

    Koltun, G.F.

    2014-01-01

    This report presents the results of a study to assess potential water availability from the Charles Mill, Clendening, Piedmont, Pleasant Hill, Senecaville, and Wills Creek Lakes, located within the Muskingum River Watershed, Ohio. The assessment was based on the criterion that water withdrawals should not appreciably affect maintenance of recreation-season pool levels in current use. To facilitate and simplify the assessment, it was assumed that historical lake operations were successful in maintaining seasonal pool levels, and that any discharges from lakes constituted either water that was discharged to prevent exceeding seasonal pool levels or discharges intended to meet minimum in-stream flow targets downstream from the lakes. It further was assumed that the volume of water discharged in excess of the minimum in-stream flow target is available for use without negatively impacting seasonal pool levels or downstream water uses and that all or part of it is subject to withdrawal. Historical daily outflow data for the lakes were used to determine the quantity of water that potentially could be withdrawn and the resulting quantity of water that would flow downstream (referred to as “flow-by”) on a daily basis as a function of all combinations of three hypothetical target minimum flow-by amounts (1, 2, and 3 times current minimum in-stream flow targets) and three pumping capacities (1, 2, and 3 million gallons per day). Using both U.S. Geological Survey streamgage data (where available) and lake-outflow data provided by the U.S. Army Corps of Engineers resulted in analytical periods ranging from 51 calendar years for Charles Mill, Clendening, and Piedmont Lakes to 74 calendar years for Pleasant Hill, Senecaville, and Wills Creek Lakes. The observed outflow time series and the computed time series of daily flow-by amounts and potential withdrawals were analyzed to compute and report order statistics (95th, 75th, 50th, 25th, 10th, and 5th percentiles) and means for

  13. Nonylphenol in pregnant women and their matching fetuses: Placental transfer and potential risks of infants

    SciTech Connect

    Huang, Yu-Fang; Wang, Pei-Wei; Huang, Li-Wei; Yang, Winnie; Yu, Ching-Jung; Yang, Shang-Han; Chiu, Hsin-Hao; Chen, Mei-Lien

    2014-10-15

    As the predominant environmental biodegradation product of nonylphenol (NP) ethoxylates and with proven estrogenic effects, NP is formed during the alkylation process of phenols. The purposes of this study were (1) to examine maternal and prenatal exposure to NP in Taiwan, (2) to determine the level of placental protection against NP exposure as well as the level of NP in breast milk, and (3) to assess the potential risk for breastfed newborns exposed to NP through the milk. Thirty pairs of maternal and fetal blood samples, placenta, and breast milk during the 1st and the 3rd months of lactation were collected. External NP exposures of these specimens were then analyzed by using high-performance liquid chromatography coupling with fluorescence detection. Next, the socio-demographics, lifestyle, delivery method, dietary and work history were collected using a questionnaire. In addition, the daily intake of NP from consuming breast milk in the 1st and 3rd months for newborns was studied through deterministic and probabilistic risk assessment methods. The geometric means and geometric standard deviation of NP levels in maternal blood, fetal cord blood, placenta, and breast milk in the 1st and 3rd months were 14.6 (1.7) ng/ml, 18.8 (1.8) ng/ml, 19.8 (1.9) ng/g, 23.5 (3.2) ng/ml, and 57.3 (1.4) ng/ml, respectively. The probabilistic percentiles (50th, 75th, and 95th) of daily intake NP in breast milk were 4.33, 7.79, and 18.39 μg/kg-bw/day in the 1st month, respectively, and were 8.11, 10.78, 16.08 μg/kg-bw/day in the 3rd month, respectively. The probabilistic distributions (5th, 25th, and 50th) of risk for infants aged 1 month old were 0.27, 0.64, and 1.15, respectively, and that for infants aged 3 month old were 0.31, 0.46, and 0.62, respectively. Through repeated exposure from the dietary intake of expectant mothers, fetuses could encounter a high NP exposure level due to transplacental absorption, partitioning between the maternal and fetal compartments. Daily NP

  14. An analysis of potential water availability from the Atwood, Leesville, and Tappan Lakes in the Muskingum River Watershed, Ohio

    USGS Publications Warehouse

    Koltun, G.F.

    2013-01-01

    This report presents the results of a study to assess potential water availability from the Atwood, Leesville, and Tappan Lakes, located within the Muskingum River Watershed, Ohio. The assessment was based on the criterion that water withdrawals should not appreciably affect maintenance of recreation-season pool levels in current use. To facilitate and simplify the assessment, it was assumed that historical lake operations were successful in maintaining seasonal pool levels, and that any discharges from lakes constituted either water that was discharged to prevent exceeding seasonal pool levels or discharges intended to meet minimum in-stream flow targets downstream from the lakes. It further was assumed that the volume of water discharged in excess of the minimum in-stream flow target is available for use without negatively impacting seasonal pool levels or downstream water uses and that all or part of it is subject to withdrawal. Historical daily outflow data for the lakes were used to determine the quantity of water that potentially could be withdrawn and the resulting quantity of water that would flow downstream (referred to as “flow-by”) on a daily basis as a function of all combinations of three hypothetical target minimum flow-by amounts (1, 2, and 3 times current minimum in-stream flow targets) and three pumping capacities (1, 2, and 3 million gallons per day). Using both U.S. Geological Survey streamgage data and lake-outflow data provided by the U.S. Army Corps of Engineers resulted in analytical periods ranging from 51 calendar years for the Atwood Lake to 73 calendar years for the Leesville and Tappan Lakes. The observed outflow time series and the computed time series of daily flow-by amounts and potential withdrawals were analyzed to compute and report order statistics (95th, 75th, 50th, 25th, 10th, and 5th percentiles) and means for the analytical period, in aggregate, and broken down by calendar month. In addition, surplus-water mass curve data

  15. Procalcitonin as a biomarker of bacterial infection in pediatric patients after congenital heart surgery

    PubMed Central

    Chakravarti, Sujata B; Reformina, Diane A; Lee, Timothy M; Malhotra, Sunil P; Mosca, Ralph S; Bhatla, Puneet

    2016-01-01

    Background: Bacterial infection (BI) after congenital heart surgery (CHS) is associated with increased morbidity and is difficult to differentiate from systemic inflammatory response syndrome caused by cardiopulmonary bypass (CPB). Procalcitonin (PCT) has emerged as a reliable biomarker of BI in various populations. Aim: To determine the optimal PCT threshold to identify BI among children suspected of having infection following CPB. Setting and Design: Single-center retrospective observational study. Materials and Methods: Medical records of all the patients admitted between January 2013 and April 2015 were reviewed. Patients in the age range of 0-21 years of age who underwent CHS requiring CPB in whom PCT was drawn between postoperative days 0-8 due to suspicion of infection were included. Statistical Analysis: The Wilcoxon rank-sum test was used for nonparametric variables. The diagnostic performance of PCT was evaluated using a receiver operating characteristic (ROC) curve. Results: Ninety-eight patients were included. The median age was 2 months (25th and 75th interquartile of 0.1-7.5 months). Eleven patients were included in the BI group. The median PCT for the BI group (3.42 ng/mL, 25th and 75th interquartile of 2.34-5.67) was significantly higher than the median PCT for the noninfected group (0.8 ng/mL, 25th and 75th interquartile 0.38-3.39), P = 0.028. The PCT level that yielded the best compromise between the sensitivity (81.8%) and specificity (66.7%) was 2 ng/mL with an area under the ROC curve of 0.742. Conclusion: A PCT less than 2 ng/mL makes BI unlikely in children suspected of infection after CHS. PMID:27212844

  16. Endogenous DNA Damage and Risk of Testicular Germ Cell Tumors

    SciTech Connect

    Cook, M B; Sigurdson, A J; Jones, I M; Thomas, C B; Graubard, B I; Korde, L; Greene, M H; McGlynn, K A

    2008-01-18

    Testicular germ cell tumors (TGCT) are comprised of two histologic groups, seminomas and nonseminomas. We postulated that the possible divergent pathogeneses of these histologies may be partially explained by variable endogenous DNA damage. To assess our hypothesis, we conducted a case-case analysis of seminomas and nonseminomas using the alkaline comet assay to quantify single-strand DNA breaks and alkali-labile sites. The Familial Testicular Cancer study and the U.S. Radiologic Technologists cohort provided 112 TGCT cases (51 seminomas & 61 nonseminomas). A lymphoblastoid cell line was cultured for each patient and the alkaline comet assay was used to determine four parameters: tail DNA, tail length, comet distributed moment (CDM) and Olive tail moment (OTM). Odds ratios (OR) and 95% confidence intervals (95%CI) were estimated using logistic regression. Values for tail length, tail DNA, CDM and OTM were modeled as categorical variables using the 50th and 75th percentiles of the seminoma group. Tail DNA was significantly associated with nonseminoma compared to seminoma (OR{sub 50th percentile} = 3.31, 95%CI: 1.00, 10.98; OR{sub 75th percentile} = 3.71, 95%CI: 1.04, 13.20; p for trend=0.039). OTM exhibited similar, albeit statistically non-significant, risk estimates (OR{sub 50th percentile} = 2.27, 95%CI: 0.75, 6.87; OR{sub 75th percentile} = 2.40, 95%CI: 0.75, 7.71; p for trend=0.12) whereas tail length and CDM showed no association. In conclusion, the results for tail DNA and OTM indicate that endogenous DNA damage levels are higher in patients who develop nonseminoma compared with seminoma. This may partly explain the more aggressive biology and younger age-of-onset of this histologic subgroup compared with the relatively less aggressive, later-onset seminoma.

  17. Gold kiwifruit consumed with an iron-fortified breakfast cereal meal improves iron status in women with low iron stores: a 16-week randomised controlled trial.

    PubMed

    Beck, Kathryn; Conlon, Cathryn A; Kruger, Rozanne; Coad, Jane; Stonehouse, Welma

    2011-01-01

    Ascorbic acid, and more recently, the carotenoids lutein and zeaxanthin have been shown to enhance Fe absorption. However, it is not clear whether Fe status improves when foods high in ascorbic acid and carotenoids are consumed with Fe-fortified meals. The present study aimed to investigate whether consuming high v. low ascorbic acid-, lutein- and zeaxanthin-rich fruit (gold kiwifruit v. banana) with Fe-fortified breakfast cereal and milk improved Fe status in women with low Fe stores. Healthy women aged 18-44 years (n 89) with low Fe stores (serum ferritin ≤ 25 μg/l and Hb ≥ 115 g/l) were randomly stratified to receive Fe-fortified breakfast cereal (16 mg Fe as ferrous sulfate), milk and either two gold kiwifruit or one banana (164 mg v. not detectable ascorbic acid; 526 v. 22·90 μg lutein and zeaxanthin, respectively) at breakfast every day for 16 weeks. Biomarkers of Fe status and dietary intake were assessed at baseline and end in the final sample (n 69). Median serum ferritin increased significantly in the kiwifruit group (n 33) compared with the banana group (n 36), with 10·0 (25th, 75th percentiles 3·0, 17·5) v. 1·0 (25th, 75th percentiles - 2·8, 6·5) μg/l (P < 0·001). Median soluble transferrin receptor concentrations decreased significantly in the kiwifruit group compared with the banana group, with - 0·5 (25th, 75th percentiles - 0·7, - 0·1) v. 0·0 (25th, 75th percentiles - 0·3, 0·4) mg/l (P = 0·001). Consumption of an Fe-fortified breakfast cereal with kiwifruit compared with banana improved Fe status. Addition of an ascorbic acid-, lutein- and zeaxanthin-rich fruit to a breakfast cereal fortified with ferrous sulfate is a feasible approach to improve Fe status in women with low Fe stores. PMID:20727238

  18. Decadal increase of organic compounds in winter and spring atmospheric aerosols in East Asia

    NASA Astrophysics Data System (ADS)

    Kundu, S.; Kawamura, K.; Kobayashi, M.; Tachibana, E.; Lee, M.; Jung, J.

    2014-12-01

    A rapid economic growth in China and other East Asian countries may have changed molecular level organic composition of atmospheric aerosols in East Asia. Molecular level composition is required to better evaluate the roles of organic aersols on climate, air quality and public health. Diacids and oxoacids account for a significant fraction of atmospheric organic matter and their secondary sources are more important than their primary sources. Atmospheric aerosol samples (n = 698) were collected during 2001-2008 at Gosan site in Jeju Island, South Korea. They were analyzed for saturated (C2-C10), unsaturated aliphatic (C4-C5), multifunctional (C3-C7) and aromatic (C8) diacids and oxoacids (C2-C9). According to monthly average concentration, oxalic acid (C2) is the most abundant followed by malonic acid (C3) and succinic acid (C4) in the homologous series of saturated diacids (C2-C10) whereas glyoxylic acid (ωC2) is most abundant in the homologous series of oxoacids (C2-C9). The monthly median, 25th percentile and 75th percentile concentrations of saturated and multifunctional diacids and oxoacids showed the highest in spring (March-May). In contrast, those concentrations for unsaturated aliphatic and aromatic diacids were observed the highest in winter (December-February). The monthly median and percentile (25th and 75th) concentrations of all diacids and oxoacids showed the second peak in the autumn (September-November) while those concentrations were recorded lowest in summer (June-August). A steady increment or decrement was not found in the monthly median and percentile (25th and 75th) concentrations of diacids and oxoacids in any month. However, the curve fitting of those concentrations over the study period shows an incremental trend for major diacids and oxoacids in winter and spring. For example, the monthly median, 25th percentile and 75th percentile concentrations of all major diacids and oxoacids increased up to 3 times from 2001 to 2008 in winter and

  19. Paleosols and climate in the southeast of the Central Russian Upland during the Middle and Late Bronze ages (the 25th-15th Centuries BC)

    NASA Astrophysics Data System (ADS)

    Demkin, V. A.; Borisov, A. V.; Udal'Tsov, S. N.

    2010-01-01

    Paleosol studies of kurgans dating back to the Middle and Late Bronze ages (the Catacomb, Pokrovskaya, and Srubnaya cultural epochs; 4500-3500 BP) have been performed within the dry steppe zone in the southeast of the Central Russian Upland. The studied kurgans occupy the upper parts of local interfluves differing in the lithology of their upper horizons. The specificity of the Middle Holocene pedogenesis as related to the local lithologic and geomorphic conditions has been characterized. During the past 4500 years, local soils have been subjected to evolutionary changes related to climatic fluctuations. These changes manifested themselves at the subtype level with substitution of dark chestnut soils for chestnut soils. The climatic conditions during the Catacomb and Pokrovskaya cultural epochs (4.5-3.8 ka BP) were more arid than those at present. The maximum aridization of the climate took place at the end of the third and the first quarter of the second millennia BC. Detailed descriptions of the morphology of kurgan bodies and buried paleosols make it possible to hypothesize about the seasons of the kurgan construction and the technology of this work.

  20. Second Language Teaching 74. Part Two of the Proceedings of the Annual Meeting of the Pacific Northwest Conference on Foreign Languages (25th, Spokane, Washington, 1974).

    ERIC Educational Resources Information Center

    Hammerly, Hector, Ed.

    The papers included in this volume cover a variety of topics of interest to the language teacher, specifically TESOL, teacher training, curriculum planning, individualized programs, the teaching of culture, teaching techniques, study abroad programs, and programmed learning. Twenty-seven of the 32 papers in the volume are included here. The…

  1. Annual report of the National Advisory Committee for Aeronautics (25th).administrative report including Technical Report nos. 645 to 680

    NASA Technical Reports Server (NTRS)

    1940-01-01

    Report includes the National Advisory Committee for Aeronautics letter of submittal to the President, summaries of the committee's activities and research accomplished, bibliographies, and financial report.

  2. "25 Years of Educational Excellence." Special Issue Commemorating the 25th Anniversary of the Journal of the Pennsylvania Black Conference on Higher Education, Inc.

    ERIC Educational Resources Information Center

    Redfern, Alicia King, Ed.

    1996-01-01

    The articles in this document are intended to be reflective of the theme "A Silver Celebration: 25 Years of Educational Excellence," and cover topics ranging from black college athletes to black real estate owners to the status of African Americans in Pennsylvania colleges and universities. They include: "The Social and Political Dimensions of…

  3. Technology & Disability: Research, Design, Practice, and Policy. Proceedings of the RESNA International Conference (25th, Minneapolis, Minnesota, June 27-July 1, 2002).

    ERIC Educational Resources Information Center

    Simpson, Richard, Ed.

    These proceedings of the 2002 annual RESNA (Association for the Advancement of Rehabilitation Technology) conference include more than 200 presentations on all facets of assistive technology, including concurrent sessions, scientific platform sessions, interactive poster presentations, computer demonstrations, and the research symposium. The…

  4. 25th anniversary article: what can be done with the Langmuir-Blodgett method? Recent developments and its critical role in materials science.

    PubMed

    Ariga, Katsuhiko; Yamauchi, Yusuke; Mori, Taizo; Hill, Jonathan P

    2013-12-01

    The Langmuir-Blodgett (LB) technique is known as an elegant method for fabrication of well-defined layered structures with molecular level precision. Since its discovery the LB method has made an indispensable contribution to surface science, physical chemistry, materials chemistry and nanotechnology. However, recent trends in research might suggest the decline of the LB method as alternate methods for film fabrication such as layer-by-layer (LbL) assembly have emerged. Is LB film technology obsolete? This review is presented in order to challenge this preposterous question. In this review, we summarize recent research on LB and related methods including (i) advanced design for LB films, (ii) LB film as a medium for supramolecular chemistry, (iii) LB technique for nanofabrication and (iv) LB involving advanced nanomaterials. Finally, a comparison between LB and LbL techniques is made. The latter reveals the crucial role played by LB techniques in basic surface science, current advanced material sciences and nanotechnologies. PMID:24302266

  5. Nuclear Science Symposium, 25th, and Symposium on Nuclear Power Systems, 10th, Washington, D.C., October 18-20, 1978, Proceedings

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Detectors of various types are discussed, taking into account drift chambers, calorimetry, multiwire proportional chambers, signal processing, the use of semiconductors, and photo/optical applications. Circuits are considered along with instrumentation for space, nuclear medicine instrumentation, data acquisition and systems, environmental instrumentation, reactor instrumentation, and nuclear power systems. Attention is given to a new approach to high accuracy gaseous detectors, the current status of electron mobility and free-ion yield in high mobility liquids, a digital drift chamber digitizer system, the stability of oxides in high purity germanium, the quadrant photomultiplier, and the theory of imaging with a very limited number of projections.

  6. The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters

    PubMed Central

    Golin, John; Ambudkar, Suresh V.

    2016-01-01

    Asymmetric ABC (ATP-binding cassette) transporters make up a significant proportion of this important superfamily of integral membrane proteins. These proteins contain one canonical (catalytic) ATP-binding site and a second atypical site with little enzymatic capability. The baker’s yeast (Saccharomyces cerevisiae) Pdr5 multidrug transporter is the founding member of the Pdr subfamily of asymmetric ABC transporters, which exist only in fungi and slime moulds. Because these organisms are of considerable medical and agricultural significance, Pdr5 has been studied extensively, as has its medically important homologue Cdr1 from Candida albicans. Genetic and biochemical analyses of Pdr5 have contributed important observations that are likely to be applicable to mammalian asymmetric ABC multidrug transporter proteins, including the basis of transporter promiscuity, the function of the non-catalytic deviant ATP-binding site, the most complete description of an in vivo transmission interface, and the recent discovery that Pdr5 is a molecular diode (one-way gate). In the present review, we discuss the observations made with Pdr5 and compare them with findings from clinically important asymmetric ABC transporters, such as CFTR (cystic fibrosis transmembrane conductance regulator), Cdr1 and Tap1/Tap2. PMID:25886173

  7. International Forum on Reactor Ageing Management (IFRAM); Proceedings of the European Engagement Workshop held in Petten, The Netherlands, 25th – 27th May 2010

    SciTech Connect

    Martin, Oliver; Bieth, Michel; Bond, Leonard J.; Carpenter, C. E.

    2010-08-14

    The report provides the proceedings of the workshop that engaged European representatives to discuss the formation of an International Forum for Reactor Aging Management. There were 29 participants who came from the following countries or international/European Organizations: IAEA, Belgium, Czech Republic, Finland, France, Germany, Hungary, The Netherlands, Romania, Slovakia, Spain, Sweden, Switzerland, Ukraine, USA and EC/JRC. There was a large variety in types of organisations, i.e. utilities, safety authorities, TVOs and research institutes, providing large variety in the presentations. The meeting supported establishing an IFRAM Global Steering Committee and moving forward with the development of this important network.

  8. Honoring the 25th anniversary of the enactment of the Drug Price Competition and Patent Term Restoration Act of 1984 (the Hatch-Waxman Act).

    THOMAS, 111th Congress

    Sen. Brown, Sherrod [D-OH

    2009-09-24

    09/24/2009 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S9853) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. JANNAF 25Th Airbreathing Propulsion Subcommittee, 37Th Combustion Subcommittee and 1St Modeling and Simulation Subcommittee Joint Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Fry, Ronald S. (Editor); Becker, Dorothy L. (Editor)

    2000-01-01

    Contents include the following: 1. Hyper-X program: Propulsion development and verification. 2. GTX program: Airbreathing launch vehicles. 3. Hypersonic technology development: Technology program overviews. Ramjet/scramjet research. 4. Hypersonic test methods: Test medium effects. 5. Advanced propulsion: RBCC engine design and performance assessments. Advanced and combined cycle engine technology.

  10. SPECIAL ISSUE DEVOTED TO THE 25th ANNIVERSARY OF THE A.M. PROKHOROV GENERAL PHYSICS INSTITUTE: Femtosecond laser optical gas breakdown microplasma: the ionisation and postionisation dynamics

    NASA Astrophysics Data System (ADS)

    Bukin, V. V.; Garnov, S. V.; Malyutin, A. A.; Strelkov, V. V.

    2007-10-01

    The formation and evolution dynamics of the laser plasma produced in the microvolumes of gases (air, nitrogen, argon, and helium) upon their multiple ionisation by high-intensity (4×1016 W cm-2) tightly focused (to a region 1.7 μm in diameter) 400-nm, 100-fs second-harmonic pulses from a Ti:sapphire laser is studied. The spatiotemporal distribution profiles of the refractive index and electron microplasma density were recorded by ultrahigh-speed interferometry. The postionisation of a femtosecond laser plasma, i.e. the growth of the electron density known after the end of the exciting laser pulse, is detected for the first time. A theoretical model is proposed, which describes the mechanism of plasma postionisation by hot photoelectrons. The results of electron density calculations are in good agreement with experimental data.

  11. Association of Small Computer Users in Education (ASCUE) Summer Conference. Proceedings (25th, North Myrtle Beach, South Carolina, June 21-25, 1992).

    ERIC Educational Resources Information Center

    Association of Small Computer Users in Education, Greencastle, IN.

    Forty-three papers from a conference on microcomputers are presented under the following headings: Computing in the Curriculum, Information and Computer Science Information; Institutional and Administrative Computing, and Management, Services, and Training. Topics of the papers include the following: telecommunications projects that work in…

  12. Proceedings of the Annual Conference of the Western Regional Home Management-Family Economics Educators (25th, Scottsdale, Arizona, November 6-8, 1985).

    ERIC Educational Resources Information Center

    Berry, Ruth E., Ed.

    These proceedings consist of 12 presentations, most of which are followed by responses or comments. The papers include: "Integrating Family Economics and Family Counseling" (Hogan; discussants Schnittgrund, Wilhelm); "A Test of the Deacon-Firebaugh Management Model" (Gage, Schmid); "Perceived Income Adequacy and Selected Financial Management…

  13. The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters.

    PubMed

    Golin, John; Ambudkar, Suresh V

    2015-05-01

    Asymmetric ABC (ATP-binding cassette) transporters make up a significant proportion of this important superfamily of integral membrane proteins. These proteins contain one canonical (catalytic) ATP-binding site and a second atypical site with little enzymatic capability. The baker's yeast (Saccharomyces cerevisiae) Pdr5 multidrug transporter is the founding member of the Pdr subfamily of asymmetric ABC transporters, which exist only in fungi and slime moulds. Because these organisms are of considerable medical and agricultural significance, Pdr5 has been studied extensively, as has its medically important homologue Cdr1 from Candida albicans. Genetic and biochemical analyses of Pdr5 have contributed important observations that are likely to be applicable to mammalian asymmetric ABC multidrug transporter proteins, including the basis of transporter promiscuity, the function of the non-catalytic deviant ATP-binding site, the most complete description of an in vivo transmission interface, and the recent discovery that Pdr5 is a molecular diode (one-way gate). In the present review, we discuss the observations made with Pdr5 and compare them with findings from clinically important asymmetric ABC transporters, such as CFTR (cystic fibrosis transmembrane conductance regulator), Cdr1 and Tap1/Tap2. PMID:25886173

  14. IEEE Conference on Software Engineering Education and Training (CSEE&T 2012) Proceedings (25th, Nanjing, Jiangsu, China, April 17-19, 2012)

    ERIC Educational Resources Information Center

    IEEE Conference on Software Engineering Education and Training, Proceedings (MS), 2012

    2012-01-01

    The Conference on Software Engineering Education and Training (CSEE&T) is the premier international peer-reviewed conference, sponsored by the Institute of Electrical and Electronics Engineers, Inc. (IEEE) Computer Society, which addresses all major areas related to software engineering education, training, and professionalism. This year, as in…

  15. Retrospect and Prospect. Proceedings of the Annual Meeting of the American Association of State Colleges and Universities (25th, Bal Harbour, Florida, November 24-26, 1985).

    ERIC Educational Resources Information Center

    American Association of State Colleges and Universities, Washington, DC.

    Proceedings of the 1985 annual meeting of the American Association of State Colleges and Universities (AASCU) are presented. Contents include: three addresses and a lecture, remarks about/from distinguished alumni who received awards, brief summaries of additional addresses, reports from AASCU officers and projects, and an agenda of the annual…

  16. Strategy for Peace 1984. The Stanley Foundation US Foreign Policy Conference Report (25th, Annapolis, Maryland, October 11-13, 1984).

    ERIC Educational Resources Information Center

    Stanley Foundation, Muscatine, IA.

    Proceedings are summarized of a conference in which 62 foreign policy professionals met to recommend strategies for peace in the areas of U.S.-Soviet competition in the Third World, space weapons and arms control, objectives of U.S. economic and security assistance, and the United States and UNESCO. Four sections focusing on each of these areas…

  17. A resolution commending the 1st Stryker Brigade Combat Team, 25th Infantry Division upon its completion of a deployment to Afghanistan in support of Operation Enduring Freedom.

    THOMAS, 112th Congress

    Sen. Begich, Mark [D-AK

    2012-05-14

    05/14/2012 Referred to the Committee on Armed Services. (text of measure as introduced: CR S3132-3133) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  18. Proceedings of the Annual Meeting of the Mid-South Educational Research Association (25th, Tuscaloosa, Alabama, November 6-8, 1996).

    ERIC Educational Resources Information Center

    Petry, John R., Ed.; McCree, Herbert L., Ed.

    This volume contains abstracts of the more than 250 discussion papers, symposia, displays, and training sessions presented at the Mid-South Educational Research Association (MSERA) 1996 annual meeting. Papers deal with elementary, secondary, and higher education, and cover a broad spectrum of educational issues. Although many papers focus on the…

  19. Promoting Educational Technology. Summary Report of the Annual Lake Okoboji Educational Media Leadership Conference (25th, Milford, Iowa, August 20-24, 1979).

    ERIC Educational Resources Information Center

    Association for Educational Communications and Technology, Washington, DC.

    This summary report of the annual conference includes statements of delegate concerns prepared for the planning committee, presentations by three resource delegates on the promotion of educational technology at different levels, and reports from seven study committees. Lucy Ainsley discussed promotion strategies at the district level, K-12; Wesley…

  20. Teaching Biochemistry at Lisbon University--Facing the Challenge of the Bologna Declaration in the 25th Anniversary of the Biochemistry Course

    ERIC Educational Resources Information Center

    Farinha, Carlos M.; Freire, Ana Ponces

    2007-01-01

    The biochemistry degree has been taught at Lisbon University for 25 years. Since its creation, the curriculum is characterized for being widely eclectic and multidisciplinary. The adoption of the concepts proposed in Europe by the Declaration of Bologna and incorporation of these ideas at Lisbon University is discussed here for the biochemistry…

  1. Land Processes Distributed Active Archive Center (LP DAAC) 25th Anniversary Recognition "A Model for Government Partnerships". LP DAAC "History and a Look Forward"

    NASA Technical Reports Server (NTRS)

    Behnke, Jeanne; Doescher, Chris

    2015-01-01

    This presentation discusses 25 years of interactions between NASA and the USGS to manage a Land Processes Distributed Active Archive Center (LPDAAC) for the purpose of providing users access to NASA's rich collection of Earth Science data. The presentation addresses challenges, efforts and metrics on the performance.

  2. Teacher Education Models in Geography: An International Comparison. Papers Prepared in Conjunction with the International Geographical Union Congress (25th, 1984).

    ERIC Educational Resources Information Center

    Marsden, Wm., Ed.

    Thirteen essays discussing how teachers are trained to teach geography in various countries are presented. The papers are: "Teacher Education in Geography: The Comparative View" (W. E. Marsden); "The Training of Geography Teachers in the People's Republic of Bulgaria" (Paulina Vekilska and Dimitar Kantchev); "Note Sur la Formation des Maitres…

  3. Lunar and planetary science XXV; Lunar and Planetary Science Conference, 25th, Houston, TX, Mar. 14-18, 1994, Abstracts of Papers. Pts. 1, 2, & 3

    NASA Astrophysics Data System (ADS)

    1994-01-01

    The present volume on lunar and planetary science discusses an experimental project regarding Martian fluvio-thermal erosion, radiative signals from the impact of Shoemaker-Levy on Jupiter, evidence for short SiC lifetimes in the ISM, and distributions of the preatmospheric sizes of Antarctic and non-Antarctic chondrites. Attention is given to the calculation of cosmic-ray exposure ages of meteorites, meteorites as differential detectors of events over a long time scale, a comparison of surface characteristics of steep-sided domes on Venus and terrestrial silicic domes, the surface and interior of Phobos, and the hypsometric distribution of impact craters on Venus. Topics addressed include impact craters as indicators of subsurface H2O on Mars, a quantitative assessment of an impact-generated ring vortex, ordinary chondrites in space and time, and a geologic map of Callisto. Also discussed are postshock cooling and annealing within L-Group ordinary chondrites, primitive material in lunar highland soils, refractory carbides in interstellar graphite, and a mineralogical instrument for planetary applications.

  4. Proceedings, joint conference of the 21st annual meeting of the American Society of Mining and Reclamation and 25th West Virginia Surface Mine Drainage Task Force symposium

    SciTech Connect

    Barnhisel, R.I.

    2004-07-01

    Topics covered include: underground mine hydrology; valley fills; acid drainage technology initiative; reforestation/forestry; passive treatment of acid mine drainage; hydrology; selenium; acid mine drainage and remining; overburden/soils; forestry in West Virginia; revegetation and wildlife; mine soils; tailings; stream restoration; chemical treatment of acid mine drainage; watershed restoration; acidity; aquaculture; and stream characterisation. The poster papers and plenary session papers are also included.

  5. [The 75th anniversary of science research and development testing centre of air medicine and military ergonomics SSRDTI of military medicine of Ministry of Defense of the RF].

    PubMed

    Bukhtiiarov, I V; Khomenko, M N; Zhdan'ko, I M

    2010-01-01

    The article presents main stages of forming Science research and development testing centre of air medicine and military ergonomics, results of researches of three main directions: medical-technical (ergonomic) supply of creation, testing and exploitation of air techniques and armament; participating in organization of combat training activity for the purposes of saving professional health, securing of combativity and professional reliability of aircraft pilots; scientific grounding of improvement of medical supply of aviation (improvement of medical control for dynamics of state of health, physiological and psychological resources of organism in course of combat training, creation of automatized diagnostic complexes and etc.). PMID:20536040

  6. S.Res.224 — 112th Congress (2011-2012) A resolution congratulating the Soil Science Society of America on its 75th anniversary.

    THOMAS, 112th Congress

    Sen. Moran, Jerry [R-KS

    2011-06-30

    06/30/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S4304-4305; text as passed Senate: CR S4304-4305; text of measure as introduced: CR S4298) (All Actions)

  7. S.Res.260 — 112th Congress (2011-2012) A resolution commemorating the 75th anniversary of the dedication of Shenandoah National Park.

    THOMAS, 112th Congress

    Sen. Webb, Jim [D-VA

    2011-09-08

    09/08/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR: S5465; text as passed Senate: CR S5465; text of measure as introduced: CR S5463) (All Actions)

  8. S.Res.545 — 112th Congress (2011-2012) A resolution commemorating the 75th Anniversary of Air Force Weather.

    THOMAS, 112th Congress

    Sen. Johanns, Mike [R-NE

    2012-08-02

    08/02/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6012-6013; text as passed Senate: CR S6012; text of measure as introduced: CR S5992) (All Actions)

  9. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XIII: Magazines.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Magazine section of these proceedings contains the following six papers: "An Analysis of 'Magazine Type': Toward an Empirically Based Typology of Magazines and Non-Newspaper Periodicals" (Marcia R. Prior-Miller); "'Redbook': Changes in Attitude and Advice 1965-1990" (Jennifer Harbour); "A Quantitative Analysis of U.S. Consumer Magazines:…

  10. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XI: Advertising.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Advertising section of the proceedings contains the following 16 papers: "Ethics of Advertising Practitioners: An Explanation Based on a Classical Theoretical Framework" (Cornelius B. Pratt and E. Lincoln James); "Sex Roles in Frightening Film Newspaper Advertisements: An Overview of the Past 50 Years" (Melissa M. Spirek); "Is Seeing Believing…

  11. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). More Miscellaneous Studies.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The More Miscellaneous Studies section of the proceedings contains the following 34 papers: "The Louisville Courier-Journal's News Content after Purchase by Gannett" (Hansen and Coulson); "Reflection of Cultural Values in Advertising: A Comparative Analysis of Taiwan and U.S. Advertising" (Zandpour and Qian); "Sex, Violence and…

  12. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XIV: Newspapers.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Newspapers section of the proceedings contains the following 11 papers: "News Items in the 'Shrinking Foreign Newshole': The Case of the New York Times" (Daniel Riffe and others); "Newspaper Coverage of Gays and Lesbians: Editors' Views of Its Longterm Effects" (Marilyn Greenwald and Joseph Bernt); "Effects of Staff Gender on Newspaper…

  13. [Compromising conscientiously with reality but not with conscience. Reflections on the occasion of 75th anniversary of A. Stampar School of Public Health].

    PubMed

    Jaksić, Zelimir

    2002-09-01

    Changes in the activities and working conditions of the A. Stampar School of Public Health are reviewed following their anniversaries in the 25-year intervals. The differences have been described in understanding of major fields of work between: (1) social medicine (people's health) and public health; (2) health education following philosophy of Enlightenment and learning in the information era; (3) formal administrative organisation stressing implementation of given laws and entrepreneurial management in a society in transition; and (4) transfer of technology through international collaboration and under pressure of market oriented globalisation. Two basic points of view are identified: a social concern as opposite to technology-oriented productivity. It is concluded that a compromise of intentions and reality was always present looking for a balance between the described points of view. In relation to the present and future activities, the necessary compromise has to be conscientious, following the idea of preventive and social orientation applied to actual living problems of people and health care, namely people's health. PMID:19705565

  14. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part VII: Television.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Television section of the proceedings contains the following 10 papers: "Financial Commitment and Performance in Local Television News: Applying the Industrial Organizational Model" (Angela Powers); "The Relationship between Censorship and the Emotional and Critical Tone of Television News Coverage of the Persian Gulf War" (John E. Newhagen);…

  15. Facts all come with a point of view: some reflections on fact and formulation from the 75th anniversary edition of the International Journal of Psycho-Analysis.

    PubMed

    Cooper, S H

    1996-04-01

    In this paper the author examines some of the varieties of definitions of fact and formulation within contemporary psychoanalytic perspectives. A common thread running throughout various definitions of fact is the way in which fact is never theory-free. An attempt is made to compare and contrast the ways in which fact and formulation are contextually bound to theory. Questions are raised about the extent to which we can claim evidential status of propositions versus viewing formulations as useful illustrations of our work. Implicit in this paper is the current tension in psychoanalytic theory between psychoanalysis as a theory of motivation and meaning. PMID:8771377

  16. Can prescription of sip-feed supplements increase energy intake in hospitalised older people with medical problems?

    PubMed

    Roberts, Margaret; Potter, Jan; McColl, John; Reilly, John

    2003-08-01

    A blinded randomised controlled trial of prescribed oral sip-feed supplements compared with routine hospital practice was undertaken in acute admissions to a geriatric medicine department. Patients were eligible for inclusion if they were admitted from home, were not obese (BMI>75th percentile), had no swallowing difficulties and were not deemed to be in the terminal stage of illness. On admission they were stratified by nutritional status (BMI<5th, >5th to <25th, >25th to <75th percentile) and randomised. The intervention group received 120 ml oral sip-feed supplement prescribed three times per d in the medicine prescription chart (22.5 g protein, 2260 kJ (540 kcal) energy/d) distributed at medication rounds for the duration of hospital stay. The control group received routine hospital care. Outcomes were patient compliance with supplement, total energy intake and nursing staff views of the method. Patients were randomised to receive supplements (n 186 of total n 381). Half had full compliance and three-quarters at least moderate compliance. Total energy intake was significantly increased, on average, in the intervention group (P=0.001). The proportion of patients meeting estimated minimum energy requirements was significantly increased (P=0.023), but was still <50 % for the sample of patients in the intervention group. The present study suggests this method is acceptable to patients and staff and improves total energy intake. However, the amount prescribed did not ensure minimum energy requirements were met in all cases. PMID:12908904

  17. Neighborhood safety and green space as predictors of obesity among preschool children from low-income families in New York City

    PubMed Central

    Lovasi, Gina S.; Schwartz-Soicher, Ofira; Quinn, James W.; Berger, Diana K.; Neckerman, Kathryn; Jaslow, Risa; Lee, Karen K.; Rundle, Andrew

    2013-01-01

    Background Neighborhood safety, green space, walkability, and sociodemographics may influence physical activity and childhood obesity. Methods Data on measured height and weight, demographic characteristics, and home ZIP code were collected from year 2004 enrollees in a means-tested preschool program in New York City. Each ZIP code was surrounded by a 400-meter buffer and characterized using data from the US census, local government departments, New York Times website, and Transportation Alternatives. Linear and Poisson models were constructed using cluster robust standard errors and adjusting for child's sex, race, ethnicity, age, and neighborhood characteristics. Results Analyses included 11,562 children ages 3–5 years living in 160 residential ZIP codes. A higher homicide rate (at the 75th vs 25th percentile) was associated with a 22% higher prevalence of obesity (95% CI for the prevalence ratio (PR): 1.05 to 1.41). A higher density of street trees (at the 75th vs 25th percentile) was associated with 12% lower prevalence of obesity (95% CI for the PR: 0.79 to 0.99). Other neighborhood characteristics did not have significant associations with childhood obesity. Conclusions Among preschool children from low-income families, neighborhood homicide rate was associated with more obesity and street tree density was associated with less obesity. PMID:23732240

  18. Does ability to walk reflect general functionality in inflammatory neuropathies?

    PubMed

    Draak, Thomas H P; Gorson, Kenneth C; Vanhoutte, Els K; van Nes, Sonja I; van Doorn, Pieter A; Cornblath, David R; van den Berg, Leonard H; Faber, Catharina G; Merkies, Ingemar S J

    2016-06-01

    The "ability to walk" is considered a benchmark for good clinical recovery and prognosis, particularly in patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). However, it has never been determined whether being "able to walk" represents general functionality. The purpose of this study was to examine whether the ability to walk outside independently reflects general functional improvement in patients with GBS, CIDP, and gammopathy-related neuropathy (MGUSP). A total of 137 patients with newly diagnosed (or relapsing) GBS (55), CIDP (59), and MGUSP (23) were serially examined (1-year). Predefined arbitrary cut-offs (so-called patients' Functional-Acceptable-Clinical-Thresholds [FACTs]) were taken at the 50th, 75th, and 90th percentile of the Inflammatory-Rasch-built-Overall-Disability-Scale (I-RODS(©) ). We determined the proportion of patients able to walk outside independently that reached the postulated cut-offs. A mean total of 85%, 39%, and 12% of all patients able to walk reached 50th, 75th, and 90th percentile thresholds, respectively. These findings were not neuropathy type related. Our findings show that assessing only one construct of functionality (e.g., walking ability) does not reflect the full scope of daily/social functional deficits perceived by patients. The ability to walk shows a patient is doing better, but not necessarily doing well. The I-RODS(©) bypasses these limitations. PMID:26968437

  19. Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes.

    PubMed

    Patel, Kashyap A; Oram, Richard A; Flanagan, Sarah E; De Franco, Elisa; Colclough, Kevin; Shepherd, Maggie; Ellard, Sian; Weedon, Michael N; Hattersley, Andrew T

    2016-07-01

    Distinguishing patients with monogenic diabetes from those with type 1 diabetes (T1D) is important for correct diagnosis, treatment, and selection of patients for gene discovery studies. We assessed whether a T1D genetic risk score (T1D-GRS) generated from T1D-associated common genetic variants provides a novel way to discriminate monogenic diabetes from T1D. The T1D-GRS was highly discriminative of proven maturity-onset diabetes of young (MODY) (n = 805) and T1D (n = 1,963) (receiver operating characteristic area under the curve 0.87). A T1D-GRS of >0.280 (>50th T1D centile) was indicative of T1D (94% specificity, 50% sensitivity). We then analyzed the T1D-GRS of 242 white European patients with neonatal diabetes (NDM) who had been tested for all known NDM genes. Monogenic NDM was confirmed in 90, 59, and 8% of patients with GRS <5th T1D centile, 50-75th T1D centile, and >75th T1D centile, respectively. Applying a GRS 50th T1D centile cutoff in 48 NDM patients with no known genetic cause identified those most likely to have a novel monogenic etiology by highlighting patients with probable early-onset T1D (GRS >50th T1D centile) who were diagnosed later and had less syndromic presentation but additional autoimmune features compared with those with proven monogenic NDM. The T1D-GRS is a novel tool to improve the use of biomarkers in the discrimination of monogenic diabetes from T1D. PMID:27207547

  20. Type 1 Diabetes Genetic Risk Score: a novel tool to discriminate monogenic and type 1 diabetes

    PubMed Central

    Patel, K A; Oram, R A; Flanagan, S E; De Franco, E; Colclough, K; shepherd, M; Ellard, S

    2016-01-01

    Distinguishing patients with monogenic diabetes from Type 1 diabetes (T1D) is important for correct diagnosis, treatment and to select patients for gene discovery studies. We assessed whether a T1D genetic risk score (T1D-GRS) generated from T1D-associated common genetic variants provides a novel way to discriminate monogenic diabetes from T1D. The T1D-GRS was highly discriminative of proven MODY (n=805) and T1D (n=1963) (ROC-AUC=0.87). A T1D-GRS of >0.280 (>50th T1D centile) was indicative of T1D (94% specificity, 50% sensitivity). We then analyzed the T1D-GRS in 242 White-European patients with neonatal diabetes (NDM) who had been tested for all known neonatal diabetes genes. Monogenic NDM was confirmed in 90%, 59% and 8% in patients with GRS <5th T1D centile, 50-75th T1D centile and >75th T1D centile, respectively. Applying a GRS 50th T1D centile cut-off in 48 NDM patients with no known genetic cause, identified those most likely to have a novel monogenic etiology by highlighting patients with probable early-onset T1D (GRS >50th T1D centile) who were diagnosed later, had less syndromic presentation but had additional autoimmune features compared to proven monogenic NDM. The T1D-GRS is a novel tool to improve the use of biomarkers in the discrimination of monogenic diabetes from T1D. PMID:27207547

  1. High lifetime and reproductive performance of sows on southern European Union commercial farms can be predicted by high numbers of pigs born alive in parity one.

    PubMed

    Iida, R; Piñeiro, C; Koketsu, Y

    2015-05-01

    Our objectives were 1) to compare reproductive performance across parity and lifetime performance in sow groups categorized by the number of pigs born alive (PBA) in parity 1 and 2) to examine the factors associated with more PBA in parity 1. We analyzed 476,816 parity records and 109,373 lifetime records of sows entered into 125 herds from 2008 to 2010. Sows were categorized into 4 groups based on the 10th, 50th, and 90th percentiles of PBA in parity 1 as follows: 7 pigs or fewer, 8 to 11 pigs, 12 to 14 pigs, and 15 pigs or more. Generalized linear models were applied to the data. For reproductive performance across parity, sows that had 15 or more PBA in parity 1 had 0.5 to 1.8 more PBA in any subsequent parity than the other 3 PBA groups ( P< 0.05). In addition, they had 2.8 to 5.4% higher farrowing rates in parities 1 through 3 than sows that had 7 or fewer PBA (P < 0.05). However, there were no differences between the sow PBA groups for weaning-to-first-mating interval in any parity (P ≥ 0.37). For lifetime performance, sows that had 15 or more PBA in parity 1 had 4.4 to 26.1 more lifetime PBA than sows that had 14 or fewer PBA (P < 0.05). Also, for sows that had 14 or fewer PBA in parity 1, those that were first mated at 229 d old (25th percentile) or earlier had 2.9 to 3.3 more lifetime PBA than those first mated at 278 d old (75th percentile) or later (P < 0.05). Factors associated with fewer PBA in parity 1 were summer mating and lower age of gilts at first mating (AFM; P < 0.05) but not reservice occurrences (P = 0.34). Additionally, there was a 2-way interaction between mated month groups and AFM for PBA in parity 1 (P < 0.05); PBA in parity 1 sows mated from July to December increased nonlinearly by 0.3 to 0.4 pigs when AFM increased from 200 to 310 d old (P < 0.05). However, the same rise in AFM had no significant effect on the PBA of sows mated between January and June (P ≥ 0.17). In conclusion, high PBA in parity 1 can be used to predict that a

  2. Pedogeochemical mapping of Al, Ba, Pb, Ti and V in soils of the Barcelona Province (Catalonia, NE Spain): relationships with soil physico-chemical properties.

    NASA Astrophysics Data System (ADS)

    Bech, J.; Reverter, F.; Tume, P.; Sokolowska, M.; Sanchez, P.; Longan, L.; Bech, J.; Zhiyanski, M.; Lansac, A.; Oliver, M. T.

    2009-04-01

    Pedogeochemical mapping is a useful tool for estimating the local background of potentially toxic elements (PTE), wich is essential for environmental regulation. The aim of this study is to estimate the levels and distribution of Al, Ba, Pb, Ti and V in surface soils of the Barcelona province (Catalonia, NE Spain) and their relationships with administrative-geographic districts, texture, pH, organic carbon and CaCO3. The studied region has a surface area of 7731 Km2. The geology is varied: granites and Paleozoic shales predominate in SE-E. and Mesozoic and Cenozoic limestones, dolomites, marlstones, gypsum and sandstones in the remainder of the studied area. 319 top soil samples (0-20 cm) were collected at 5 km intervals on a regular grid, dried and sieved (2mm). General soil properties were analysed by standard methods. Aqua regia digests (DIN 38414-S7) of Al, Ba, Pb, Ti and V were determined by Inductively Coupled Plasma Spectrometry. Statistical data treatment was carried out using SPSS 12.0 and Statgraphics Plus 5.1. We applied Exploratory Data Analysis (EDA) techniques to statistically describe the data. The software used for mapping was ESRI's Arc Wiew 9.0, Desktop version. Analytical data is represented using growing dot maps. The values of every mapped variable were grouped into a few cartographic classes in order to produce limited legends. The limits for the cartographic classes were chosen by the percentile method (5th, 25th, 50th, 75th, 90th, and 98th). Some results are: Al mg kg-1min 4410.0, max 194786.0, mean 18145.6, sd 12112.1, med 16273.3 ; Ba mgkg-1min 7.32, max 1709.0, mean 128.4, sd 149.2, med 91.7; Pb mg kg-1min 2.76, max 485.7, mean 52.2, sd 46.3, med 46.0; Ti mg kg-1min 11.6, max 3540.0, mean 268.0, sd 421.6, med 132.2, and V mg kg-1min 2.15, max 289.2, mean 31.4, sd 25.7, med 26.0. . The highest mean value of Ba (328mkg-1), Pb (139.6 mgkg-1) and V (54.7 mgkg-1) corresponds to the Barcelonés district with mainly urban soils. The Al contents

  3. Trigeminal Electrophysiology: a 2 × 2 matrix model for differential diagnosis between temporomandibular disorders and orofacial pain

    PubMed Central

    2010-01-01

    Background Pain due to temporomandibular disorders (TMDs) often has the same clinical symptoms and signs as other types of orofacial pain (OP). The possible presence of serious neurological and/or systemic organic pathologies makes differential diagnosis difficult, especially in early disease stages. In the present study, we performed a qualitative and quantitative electrophysiological evaluation of the neuromuscular responses of the trigeminal nervous system. Using the jaw jerk reflex (JJ) and the motor evoked potentials of the trigeminal roots (bR-MEPs) tests, we investigated the functional and organic responses of healthy subjects (control group) and patients with TMD symptoms (TMD group). Method Thirty-three patients with temporomandibular disorder (TMD) symptoms and 36 control subjects underwent two electromyographic (EMG) tests: the jaw jerk reflex test and the motor evoked potentials of the trigeminal roots test using bilateral electrical transcranial stimulation. The mean, standard deviation, median, minimum, and maximum values were computed for the EMG absolute values. The ratio between the EMG values obtained on each side was always computed with the reference side as the numerator. For the TMD group, this side was identified as the painful side (pain side), while for the control group this was taken as the non-preferred masticatory side (non-preferred side). The 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were also calculated. Results Analysis of the ratios (expressed as percentages) between the values obtained on both sides revealed a high degree of symmetry in the bR-MEPs % in the control (0.93 ± 0.12%) and TMD (0.91 ± 0.22%) groups. This symmetry indicated organic integrity of the trigeminal root motor fibers and correct electrode arrangement. A degree of asymmetry of the jaw jerk's amplitude between sides (ipJJ%), when the mandible was kept in the intercuspal position, was found in the TMD group (0.24% ± 0.14%) with a statistically

  4. Too old to have children? Lessons from natural fertility populations

    PubMed Central

    Eijkemans, Marinus J.C.; van Poppel, Frans; Habbema, Dik F.; Smith, Ken R.; Leridon, Henri; te Velde, Egbert R.

    2014-01-01

    STUDY QUESTION Is it possible to construct an age curve denoting the ages above which women are biologically too old to reproduce? SUMMARY ANSWER We constructed a curve based on the distribution of female age at last birth in natural fertility populations reflecting the ages above which women have become biologically too old to have children. WHAT IS KNOWN ALREADY The median age at last birth (ALB) for females is ∼40–41 years of age across a range of natural fertility populations. This suggests that there is a fairly universal pattern of age-related fertility decline. However, little is known about the distribution of female ALB and in the present era of modern birth control, it is impossible to assess the age-specific distribution of ALB. Reliable information is lacking that could benefit couples who envisage delaying childbearing. STUDY DESIGN, SIZE, DURATION This study is a review of high-quality historical data sets of natural fertility populations in which the distributions of female age at last birth were analysed. The studies selected used a retrospective cohort design where women were followed as they age through their reproductive years. PARTICIPANTS/MATERIALS, SETTING, METHODS Using a common set of eligibility criteria, large data files of natural fertility populations were prepared such that the analysis could be performed in parallel across all populations. Data on the ALB and confounding variables are presented as box and whisker plots denoting the 5th, 25th, 50th, 75th and 95th percentile distribution of the age at last birth for each population. The analysis includes the estimation of Kaplan–Meier curves for age at last birth of each population. The hazard curve for ALB was obtained by plotting the smoothed hazard curve of each population and taking the lowest hazard within a time period of at least 5 years. This lowest hazard curve was then transformed into a cumulative distribution function representing the composite curve of the end of

  5. Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday

    NASA Astrophysics Data System (ADS)

    Dowker, Fay; Elizalde, Emilio; Kirsten, Klaus

    2012-09-01

    John Stuart Dowker was born in Sheffield, Yorkshire, on 18 March 1937. His life, therefore, was very much influenced by the Second World War. This is evident as his father died on active service in 1945, after being called up in 1941. His grandfather also died shortly afterwards, so he did not know either of them very well. Nevertheless, it seems that he picked up a positive attitude towards natural sciences as both were technically minded. His mother later provided, often from borrowed money, all the necessary intellectual food in forms of chemistry sets, slide rules and other things that a boy needed to develop his interests. Stuart scored excellently in the 11-plus exam, which was used to decide the type of school a pupil should attend after primary school. Although Stuart was generally allowed to do what he wanted, his mother insisted that he chose King Edward VII Grammar School (KES), the top school in Sheffield at the time. KES allowed Stuart to fully develop his intellectual abilities, and after the S-level exam he received a prestigious state scholarship which allowed him to study at any university in the country. He picked Nottingham over other possibilities, mainly because of his interest in electronics and because of the relative proximity to his family. In Nottingham, where he stayed from 1955 to 1958, his research concentration turned out to be mostly solid state physics. But with time on his hands, Stuart raided the library and taught himself things like complex analysis and quantum mechanics, with de Broglie's La mécanique ondulatoire [1] as one of his favorites. Remarkably, this book already contains a discussion of quantization on curved configuration spaces, a setting so relevant in Stuart's later career. Stuart wanted to investigate quantum field theory for his doctoral thesis. So he wrote, among others, to Rudolph Peierls in Birmingham, and, after being interviewed by Peierls himself and J G Valatin, he received an offer of a PhD position. He went to Birmingham in 1958, where his supervisor was Leonardo Castillejo, best known from the Castillejo-Dalitz-Dyson-ambiguity see [2]. His thesis involved stripping theory, and on this topic he wrote his first ever publication [3]. Takeaways from that time were that sometimes one simply has to do what one is told, and even more importantly, sometimes one has to get on with a calculation and 'just roll through it'. It was also around that period that Stuart started to learn quantum field theory properly following the developments of Feynman. After his PhD, it was Peierls who helped him to find a position at the University of Pennsylvania in Philadelphia in 1961, which he accepted before he received an offer from CERN. In retrospect, this was probably fortunate as it is where he met his wife, Pwu Yih, to whom he has been married for nearly 50 years. Scientifically he remained somewhat isolated there and spent much of his time learning more about quantum field theory, for example by reading Bogoliubov and Shirkov [4]. His entry point for general relativity was Eddington's The Mathematical Theory of Relativity [5], which together with the works of Julian Schwinger and Bryce de Witt were the most influential ones at that time. A shift of focus to questions in quantum field theory in curved space time took place. After his stay in Philadelphia, in 1963, helped by connections between Abe Klein and Brian Flowers, he went to the University of Manchester, where he remains to this day. This period was only briefly interrupted by a sabbatical in 1978 to 1979 at Austin following an invitation by Bryce de Witt. Looking back, it seems there were two major driving forces or principles that determined much of Stuart's selection of research projects. One of them is the method of images, about which he says: '...it intrigued me that one problem (charge + plane) could be got from another (just charge) by geometrical reasoning plus uniqueness. Thomson's book [6] took this further. Chapter 5 is devoted to the image and inversion methods and I must have read this closely as there ar

  6. Does Behavioral Style Influence Learning Strategy in Health Professions Students?

    PubMed

    Williamson, J W; Krumwiede, K H; Reed, JoyLynn; Farmer, Suzanne; Behrendt, William

    2015-01-01

    Proficiency in areas of task completion, information processing, and time management are important attributes for successful academic performance and can be assessed using the Learning Assessment Study Strategies Inventory (LASSI). The purpose of this study was to determine if there were differences in learning strategies across four behavioral profiles using the DISC style analysis (Dominance, Influence, Steadiness, Compliance). Graduate health professions students (n=247) were administered the DISC and LASSI to assess study strategy categories based on their natural DISC behavioral style. A one-way ANOVA was used to assess differences for 10 LASSI category scores across the four DISC profiles; scores were also compared with national percentile scores. The D and C profiles were above the 75th percentile for information processing, but below the 50th percentile for self-testing. The S profile had significantly lower scores (p<0.005) for information processing and was below the 50th percentile for anxiety (i.e., higher anxiety). The I profile was below the 50th percentile for time management and concentration to academic tasks. The data are in close agreement with recognized behaviors specific for each behavioral style and suggest that behavioral style should be considered an important factor in academic performance. PMID:26342613

  7. Oxidative stress and nitric oxide are increased in obese children and correlate with cardiometabolic risk and renal function.

    PubMed

    Correia-Costa, Liane; Sousa, Teresa; Morato, Manuela; Cosme, Dina; Afonso, Joana; Areias, José C; Schaefer, Franz; Guerra, António; Afonso, Alberto C; Azevedo, Ana; Albino-Teixeira, António

    2016-09-01

    Oxidative stress and nitric oxide (NO) appear to represent important links between obesity and cardiovascular, metabolic and/or renal disease. We investigated whether oxidative stress and NO production/metabolism are increased in overweight and obese prepubertal children and correlate with cardiometabolic risk and renal function. We performed a cross-sectional evaluation of 313 children aged 8-9 years. Anthropometrics, 24-h ambulatory blood pressure, pulse wave velocity (PWV), insulin resistance (homoeostasis model assessment index (HOMA-IR)), inflammatory/metabolic biomarkers, estimated glomerular filtration rate (eGFR), plasma total antioxidant status (TAS), plasma and urinary isoprostanes (P-Isop, U-Isop), urinary hydrogen peroxide (U-H2O2), and plasma and urinary nitrates and nitrites (P-NOx, U-NOx) were compared among normal weight, overweight and obese groups, according to WHO BMI z-score reference. U-Isop were increased in the obese group, whereas U-NOx were increased in both overweight and obese children. U-Isop were positively correlated with U-H2O2, myeloperoxidase (MPO), high-sensitivity C-reactive protein, HOMA-IR and TAG. TAS correlated negatively with U-Isop and MPO and positively with PWV. HOMA-IR and U-H2O2 were associated with higher U-Isop, independently of BMI and eGFR, and total cholesterol and U-H2O2 were associated with U-NOx, independently of BMI, eGFR values and P-NOx concentration. In overweight and obese children, eGFR decreased across P-NOx tertiles (median: 139·3 (25th, 75th percentile 128·0, 146·5), 128·0 (25th, 75th percentile 121·5, 140·4), 129·5 (25th, 75th percentile 119·4, 138·3), P for linear trend=0·003). We conclude that oxidant status and NO are increased in relation to fat accumulation and, even in young children, they translate into higher values of cardiometabolic risk markers and affect renal function. PMID:27480380

  8. A resolution recognizing the 50th anniversary of the ratification of the Treaty of Mutual Security and Cooperation with Japan, and affirming support for the United States-Japan security alliance and relationship.

    THOMAS, 111th Congress

    Sen. Webb, Jim [D-VA

    2010-06-23

    06/29/2010 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (consideration: CR S5630; text as passed Senate: CR S5630) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  9. S.Res.72 — 112th Congress (2011-2012) A resolution recognizing the artistic and cultural contributions of the Alvin Ailey American Dance Theater and the 50th Anniversary of the first performance of Alvin Ailey's masterwork, "Revelations".

    THOMAS, 112th Congress

    Sen. Gillibrand, Kirsten E. [D-NY

    2011-02-17

    02/17/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S924-926; text as passed Senate: CR S924; text of measure as introduced: CR S917-918) (All Actions)

  10. N-Phosphoryl Amino Acids and Biomolecular Origins. Review Paper in Honor of the 50th Anniversary of the Publication of ``A Production of Amino Acids under Possible Primitive Earth Conditions'' (Miller, 1953)

    NASA Astrophysics Data System (ADS)

    Cheng, C. M.; Liu, X. H.; Li, Y. M.; Ma, Y.; Tan, B.; Wan, R.; Zhao, Y. F.

    2004-10-01

    The possible role of phosphoryl amino acids for biomolecular origins is briefly reviewed. Peptide formation, ester formation, ester exchange on phosphorus and N to O migration occurred when the N-phosphoryl amino acid was incubated at room temperature. Short nucleotides and peptides were formed when nucleoside was reacted with N-phosphoryl amino acid at room temperature. Serine and threonine residues in their conjugate with different nucleosides (mediated with phosphorus) showed different self-cleavage activities. N-phosphoryl Histine and Ser-His dipeptide could cleave nucleic acids, proteins and esters in neutral medium. Based on a simple model, a pathway of `co-evolution of protein and nucleic acid' was proposed.

  11. S.Res.377 — 112th Congress (2011-2012) A resolution recognizing the 50th anniversary of the historic achievement of John Herschel Glenn, Jr., in becoming the first United States astronaut to orbit the Earth.

    THOMAS, 112th Congress

    Sen. Brown, Sherrod [D-OH

    2012-02-15

    02/15/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S690-692; text as passed Senate: CR S690-691; text of measure as introduced: CR S703-704) (All Actions)

  12. Celebration of the 50th anniversary of the foundation of the French society for connective tissue research. Its short history in the frame of the origin and development of this discipline.

    PubMed

    Borel, J P; Maquart, F X; Robert, A M; Labat-Robert, J; Robert, L

    2012-02-01

    The science of connective tissues has (at least) a double origin. Collagen, their major constituent was first studied in conjunction with the leather industry. Acid mucopolysaccharides (now glycosaminoglycans) were characterised by (bio)-chemists interested in glycoconjugates. They joined mainly hospital-based rheumatology departments. Later started the study of elastin with the discovery of elastases and of connective tissue-born (structural) glycoproteins. Besides rhumatologists and leather-chemists mainly pathologists became involved in this type of research, followed closely by ophthalmology research. The first important meetings of these diverse specialists were organised under the auspices of NATO, first in Saint-Andrew's in GB in 1964 and a few years later (1969) in Santa Margareta, Italy. With the discovery of fibronectin, a "structural glycoprotein", started the study of cell-matrix interactions, reinforced by the identification of cell-receptors mediating them and the "cross-talk" between cells and matrix constituents. The first initiative to organise societies for this rapidly growing discipline was that of Ward Pigman in New York in 1961, restricted however to glycol-conjugates. Next year, in 1962 was founded the first European Connective Tissue Society in Paris: the "Club français du tissu conjonctif", which played a crucial role in the establishment of schools, laboratories, national and international meetings in the major cities of France: Paris, Lyon, Reims, Caen,Toulouse. A second European society was born in Great Britain, and at a joint meeting with the French society at the Paris Pasteur Institute, was founded in 1967 by these societies the Federation of European Connective Tissue Societies (FECTS). Their meetings, organised every second year, drained a wide attendance from all over the world. An increasing number of young scientists joined since then this branch of biomedical discipline with several international journals devoted to connective tissue research, to matrix biology. The increasing number and quality of the young generation of scientists engaged in research related to the extracellular matrix or better Biomatrix and cell-matrix interactions is a further guarantee for the continued interest in this crucial field of science at the interface of basic and medically oriented research. PMID:22265965

  13. Continuing Higher Education: In Retrospect and toward the Future. Proceedings of the Annual Meeting, Association for Continuing Higher Education (50th, Salt Lake City, Utah, October 30-November 2, 1988).

    ERIC Educational Resources Information Center

    Jackson, Jan, Ed.

    These proceedings contain addresses and summaries of presentations made in concurrent sessions at the annual meeting. The addresses are: Association for Continuing Higher Education (ACHE)--Then and Now: What Our Past Has To Tell Us about Our Future" (Nelcamp and others); "A Conversation with Alex Haley" (Haley); "Luncheon Address of…

  14. S.Res.576 — 112th Congress (2011-2012) A resolution celebrating the 50th anniversary of the signing of Public Law 87-788, an Act commonly known as the McIntire-Stennis Cooperative Forestry Act.

    THOMAS, 112th Congress

    Sen. Cochran, Thad [R-MS

    2012-09-22

    09/22/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR 9/21/2012 S6679-6684; text as passed Senate: CR 9/21/2012 S6680; text of measure as introduced: CR 9/21/2012 S6630) (All Actions)

  15. DESIGN AND CONSTRUCTION OF SCHOOL BUILDINGS. PROCEEDINGS, ASSOCIATION OF SCHOOL BUSINESS OFFICIALS OF THE UNITED STATES AND CANADA, ANNUAL MEETING AND EDUCATIONAL EXHIBIT, (50TH SAN FRANCISCO, CALIFORNIA, OCTOBER 71-22, 1964).

    ERIC Educational Resources Information Center

    LIEBESKIND, MORRIS

    PROBLEMS IN THE SCHEDULING AND COMPLETION OF SCHOOL BUILDING DESIGN AND CONSTRUCTION PROJECTS ARE DISCUSSED WITH REFERENCE TO THE CRITICAL PATH METHOD OF PROGRAMING. THE DISCUSSION GIVES A BROAD OVERVIEW OF THE METHOD WITH DETAILED SUGGESTIONS FOR SCHOOL ADMINISTRATORS. SPECIFIC SUBJECT AREAS INCLUDE--(1) CPM, A NEW MANAGEMENT TOOL, (2) CPM…

  16. A resolution celebrating the 50th anniversary of the signing of Public Law 87-788, an Act commonly known as the McIntire-Stennis Cooperative Forestry Act.

    THOMAS, 112th Congress

    Sen. Cochran, Thad [R-MS

    2012-09-22

    09/22/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR 9/21/2012 S6679-6684; text as passed Senate: CR 9/21/2012 S6680; text of measure as introduced: CR 9/21/2012 S6630) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  17. Theodor Billroth's vision and Karl Ziegler's action: commemoration of the 40th day of death and the 50th anniversary of conferment of Nobel Prize for Chemistry of Karl Ziegler.

    PubMed

    Kapischke, Matthias; Pries, Alexandra

    2014-02-01

    Alloplastic materials are broadly used in modern surgery. Until the middle of the 20th century, metal materials and especially silver were used because of their antimicrobial properties. With the development of a new catalytic process for the production of high-density polyethylene and polypropylene materials, a new era of prosthesis was introduced. These polymers are integral part of our everyday operations surgery, especially in hernia repair. The famous surgeon Billroth mentioned to his pupil Czerny in 1878: "If we could artificially produce tissues of the density and toughness of fascia and tendon, the secret of the radical cure of hernia would be discovered". The polypropylene developed by Karl Ziegler gave the surgeon a material for daily practice, which in its properties (nearly) achieved Billroth's initial vision. In 1963 the Nobel Prize for Chemistry was awarded to Karl Ziegler and Giulio Natta in Stockholm. Furthermore, August 11, 2013 will be the 40th anniversary of Karl Ziegler's death. This manuscript honors both days. PMID:24387785

  18. News and Views: Extrasolar mineralogy; ESO's 50th birthday; VISTA views a vast ball of stars; First instrument ready for JWST; PCs can process Pan-STARRS1 images at home; JIVE goes to SA

    NASA Astrophysics Data System (ADS)

    2012-06-01

    After more than 10 years of work by more than 200 engineers, the Mid InfraRed Instrument (MIRI) is the first of four instruments to be completed for the James Webb Space Telescope, whose design and construction has been led by Britain in partnership with European institutions. Images from the Panoramic Survey Telescope & Rapid Response System (Pan-STARRS) will be processed using distributed computer time through theSkyNet, a “citizen science” programme developed for radio data by the International Centre for Radio Astronomy Research (ICRAR).

  19. Can Professional Environments in Schools Promote Teacher Development? Explaining Heterogeneity in Returns to Teaching Experience

    PubMed Central

    Kraft, Matthew A.; Papay, John P.

    2014-01-01

    Although wide variation in teacher effectiveness is well established, much less is known about differences in teacher improvement over time. We document that average returns to teaching experience mask large variation across individual teachers and across groups of teachers working in different schools. We examine the role of school context in explaining these differences using a measure of the professional environment constructed from teachers responses to state-wide surveys. Our analyses show that teachers working in more supportive professional environments improve their effectiveness more over time than teachers working in less supportive contexts. On average, teachers working in schools at the 75th percentile of professional environment ratings improved 38% more than teachers in schools at the 25th percentile after 10 years. PMID:25866426

  20. Incubation Periods of Mosquito-Borne Viral Infections: A Systematic Review

    PubMed Central

    Rudolph, Kara E.; Lessler, Justin; Moloney, Rachael M.; Kmush, Brittany; Cummings, Derek A. T.

    2014-01-01

    Mosquito-borne viruses are a major public health threat, but their incubation periods are typically uncited, non-specific, and not based on data. We systematically review the published literature on six mosquito-borne viruses selected for their public health importance: chikungunya, dengue, Japanese encephalitis, Rift Valley fever, West Nile, and yellow fever viruses. For each, we identify the literature's consensus on the incubation period, evaluate the evidence for this consensus, and provide detailed estimates of the incubation period and distribution based on published experimental and observational data. We abstract original data as doubly interval-censored observations. Assuming a log-normal distribution, we estimate the median incubation period, dispersion, 25th and 75th percentiles by maximum likelihood. We include bootstrapped 95% confidence intervals for each estimate. For West Nile and yellow fever viruses, we also estimate the 5th and 95th percentiles of their incubation periods. PMID:24639305

  1. Infant birth weight and third trimester maternal plasma markers of vascular integrity: the MIREC study

    PubMed Central

    Kumarathasan, Premkumari; Vincent, Renaud; Bielecki, Agnieszka; Blais, Erica; Blank, Katrin; Das, Dharani; Karthikeyan, Subramanian; Cakmak, Sabit; Fisher, Mandy; Arbuckle, Tye; Fraser, William

    2016-01-01

    Abstract Background: There is paucity of information on mechanisms constituting adverse birth outcomes. We assessed here the relationship between vascular integrity and adverse birth effects. Methods and results: Third trimester maternal plasma (n = 144) from the Maternal-Infant Research on Environmental Chemicals Study (MIREC) was analysed for vascular, inflammatory and oxidative stress markers by HPLC-fluorescence, protein array and EIA method. Analysis of the <25th and >75th percentile birth weight subgroups revealed markers associated with birth weight (ETs, MMP-9, VEGF, and 8-isoPGF-2α) and gestational age (ET-1, MMP-2, and VEGF). Conclusions: Mechanistic insights into adverse birth outcome pathways can be achieved by integrating information on multiple biomarkers, physiology using systems biology approach. PMID:26900787

  2. Proceedings of the 27th International Group for the Psychology of Mathematics Education Conference Held Jointly with the 25th PME-NA Conference (Honolulu, Hawaii, July 13-18, 2003). Volume 4

    ERIC Educational Resources Information Center

    Pateman, Neil A., Ed; Dougherty, Barbara J., Ed.; Zilliox, Joseph T., Ed.

    2003-01-01

    This volume of the 27th International Group for the Psychology of Mathematics Education Conference includes the following research reports: (1) Improving Decimal Number Conception by Transfer from Fractions to Decimals (Irita Peled and Juhaina Awawdy Shahbari); (2) The Development of Student Teachers' Efficacy Beliefs in Mathematics during…

  3. A Selection of Papers from NWAVE [New Ways of Analyzing Variation] (25th, Las Vegas, Nevada, October 1996). University of Pennsylvania Working Papers in Linguistics, Volume 4, Number 1.

    ERIC Educational Resources Information Center

    Boberg, Charles, Ed.; Meyerhoff, Miriam, Ed.; Strassel, Stephanie, Ed.

    This issue includes the following articles: "Towards a Sociolinguistics of Style" (Alan Bell, Gary Johnson); "Engendering Identities: Pronoun Selection as an Indicator of Salient Intergroup Identities" (Miriam Meyerhoff); "A Majority Sound Change in a Minority Community" (Carmen Fought); "Addressing the Actuation Question for Local Linguistic…

  4. The Future Is Now: The Role of Institutional Research in Campus Transformation: Proceedings of the Annual Conference of the North East Association for Institutional Research (25th, Philadelphia, Pennsylvania, November 14-17, 1998).

    ERIC Educational Resources Information Center

    North East Association for Institutional Research.

    This proceedings document is comprised of the 17 papers, panel presentations, and work shares presented at a 1998 conference on institutional research. The papers are: (1) "Description of the UDAES Project: A Study of Undergraduate Academic Experiences" (Karen W. Bauer); (2) "Transforming Your Campus: Mixed Methodology in Institutional Research"…

  5. Proceedings of the 27th International Group for the Psychology of Mathematics Education Conference Held Jointly with the 25th PME-NA Conference (Honolulu, Hawaii, July 13-18, 2003). Volume 2

    ERIC Educational Resources Information Center

    Pateman, Neil A., Ed.; Dougherty, Barbara J., Ed.; Zilliox, Joseph T., Ed.

    2003-01-01

    This volume of the 27th International Group for the Psychology of Mathematics Education Conference presents the following research reports: (1) Text Talk, Body Talk, Table Talk: A Design of Ratio and Proportion as Classroom Parallel Events (Dor Abrahamson); (2) Generalizing the Context and Generalising the Calculation (Janet Ainley); (3) Interview…

  6. NATCON Papers 1999 = Les Actes du CONAT. [Papers Presented at the Annual Meeting of the National Consultation on Career Development (NATCON) (25th, Ottawa, Ontario, Canada, January 25-27, 1999)].

    ERIC Educational Resources Information Center

    National Consultation on Career Development (NATCON), Toronto (Ontario).

    This book contains the texts of a number of presentations from the 1999 NATCON conferences. These papers are: (1) "A Book of Surprises: Games, Stories, and Magic for Career Practitioners" (E. Sylvester); (2) "Academic and Career Choices for Lesbian and Gay Young Adults" (M. Schneider and J. McCurdy-Myers); (3)"Adolescent Values Development:…

  7. Multidisciplinary Investigations of the Galápagos Rift, 86°W to 89.5°W: 25th Anniversary of the Discovery of Hydrothermal Venting

    NASA Astrophysics Data System (ADS)

    Hammond, S. R.; Shank, T. M.; Fornari, D. J.; Yoerger, D. R.; Bradley, A. M.; Scheirer, D. S.; Tivey, M. A.

    2002-12-01

    In May-June, 2002, a multidisciplinary expedition comprised of biologists, chemists, geologists and engineers conducted a field program on the Galápagos Rift between 86°W and 89.5°W. Objectives of the expedition included revisiting the site of one of the first-discovered low-temperature hydrothermal vents at Rose Garden (originally found in 1979), and searching for new low- and high-temperature vents along the largely unexplored western portion of the Galápagos Rift to 89.5°W. The field work was funded primarily by NOAA's Ocean Exploration Program with additional support from the National Science Foundation and Woods Hole Oceanographic Institution. A synergistic array of deep-ocean vehicles was used for the exploration program. Alvin and a new digital towed camera were used for making seafloor observations, acquiring digital imagery and collecting samples. An autonomous vehicle ABE (Autonomous Benthic Explorer), which acquired meter-scale bathymetry, near-bottom magnetics and bottom water-properties data, was utilized to explore for active hydrothermal venting. Water-column vertical casts and tow-yos with a CTD/rosette were used to explore for plumes emanating from high-temperature vents. Alvin and ABE were used to explore for the Rose Garden vent field near 86°13.5'W. Detailed bottom-water temperature maps and seafloor magnetics data, in conjunction with visual and photographic observations from Alvin and the towed camera, confirmed that the Rose Garden vent field and associated animal community no longer exists, and that prolonged high-temperature venting appears to never have occurred in this area. However, a new low-temperature vent field (which was named Rosebud) was discovered nearby at a depth of 2450 m, and was found to be developing on a fresh-looking sheet flow at a location approximately 200 m northwest of the former Rose Garden area. A second site of low-temperature hydrothermal activity, at 1670 m, was discovered on a portion of the unexplored rift near 89.5°W. This venting is the first discovered along this portion of the Galápagos Rift and it hosts a large vesicomyid (C. magnifica) clam community that covers an approximately 60 m x 60 m area. Throughout the cruise, ABE was used during night operations to provide synoptic micro-bathymetry maps, magnetics data and bottom water properties. Early each morning, these data were processed and then provided to the Alvin observers prior to that same day's dive. ABE data were occasionally combined with, or supplanted by, data from the towed camera or the CTD. A total of 9 Alvin dives, 7 ABE dives, 5 camera tows and 6 CTD tows/casts were conducted. Detailed micro-bathymetric maps and mosaics of the vent communities will be presented.

  8. A case of selective impairment of encyclopaedic numerical knowledge or ‘when December 25th is no longer Christmas day, but ‘20 + 5’ is still 25’

    PubMed Central

    Cappelletti, Marinella; Jansari, Ashok; Kopelman, Michael; Butterworth, Brian

    2008-01-01

    This study investigates encyclopaedic numerical knowledge in a patient with a presumed left temporal dysfunction, associated with temporal lobe epilepsy. Encyclopaedic numbers are those used as nominal labels (such as in ‘British Broadcasting Corporation – BBC 1’ or ‘Levis 501’) to express familiar or historical dates (e.g., our birthday or the French revolution, 1789) and to indicate other general or autobiographical numerical information (e.g., Personal Identification numbers – PINs, post-codes, telephone numbers). We showed a dissociation between impaired processing of encyclopaedic numbers and preserved processing of non-encyclopaedic numbers (e.g., the larger between 54 and 65 or the result of ‘6 × 9’). This dissociation complements the existing data showing the reverse pattern of performance, namely an advantage for encyclopaedic compared to non-encyclopaedic numbers. These data add important information on an aspect of numerical processing that has not yet been systematically explored and reinforce the distinction between numerical and non-numerical knowledge in the semantic system. PMID:18387561

  9. Proceedings of the 27th International Group for the Psychology of Mathematics Education Conference Held Jointly with the 25th PME-NA Conference (Honolulu, Hawaii, July 13-18, 2003). Volume 1

    ERIC Educational Resources Information Center

    Pateman, Neil A., Ed; Dougherty, Barbara J., Ed.; Zilliox, Joseph T., Ed.

    2003-01-01

    This volume of the 27th International Group for the Psychology of Mathematics Education Conference presents papers from: plenary panels; research forums; working sessions; discussion groups; short oral communications; and poster sessions from the meeting. Plenary lectures included: (1) Studying and Capturing the Complexity of Practice: The Case of…

  10. Vision, Invention, Intervention: Celebrating Adult Education. Conference Proceedings. Papers from the Annual Conference of the Standing Conference on University Teaching and Research in the Education of Adults (25th, Winchester, England, United Kingdom, July 11-13, 1995).

    ERIC Educational Resources Information Center

    Bryant, Ian, Ed.

    The papers in these proceedings include a number of themes such as enduring and progressive social change, good practice and positive outcomes, and strategies of survival, resistance and subversion. They are: "Achievement, Personal Development, and Positive Outcomes" (Viv Anderson); "Raising Standards" (Paul Armstrong); "Multicultural Education…

  11. Rocket and space technology - The ideas of K.E. Tsiolkovsky and modern development; Lectures Devoted to K.E. Tsiolkovsky's Ideas, 25th, Kaluga, Russia, Sept. 11-14, 1990, Transactions

    NASA Astrophysics Data System (ADS)

    Moshkin, E. K.; Balashov, V. V.; Kaznevskii, V. P.; Merkulov, I. A.

    The papers presented in this volume focus on recent theoretical and experimental research related to rocket and space technology. Topics discussed include the problem of earthquake prediction by space methods, mathematical support of geophysical experiments conducted at the Mir orbital complex, local stationary orbits of artificial earth satellites, and terminal guidance of a gliding flight vehicle on the basis of the angle of roll at the final stage of descent. Attention is also given to a new method for determining the number of flight vehicle prototypes subject to full-scale testing, optimal damping of the vibrations of the elastically attached fragments of large-scale space structures, and generation of artificial gravity in two-mass systems without balancing. (For individual items see A93-18307 to A93-18324)

  12. How To Write Good Science Books for Children & Youths. Asian Cultural Center Training Course on Book Production in Asia and the Pacific (25th, Tokyo, Japan, October 30-November 16, 1992).

    ERIC Educational Resources Information Center

    Asian Cultural Centre for UNESCO, Tokyo (Japan).

    It is of critical importance in the Asia/Pacific region to produce quality science books which are attractive and interesting for children and youths and which can also stimulate their interest in science and provide them with accurate scientific knowledge in an easily understandable way. This publication is a report of a training course on book…

  13. Proceedings of the 27th International Group for the Psychology of Mathematics Education Conference Held Jointly with the 25th PME-NA Conference (Honolulu, Hawaii, July 13-18, 2003). Volume 3

    ERIC Educational Resources Information Center

    Pateman, Neil A., Ed; Dougherty, Barbara J., Ed.; Zilliox, Joseph T., Ed.

    2003-01-01

    This volume of the 27th International Group for the Psychology of Mathematics Education Conference includes the following research reports: (1) The Affective Views of Primary School Children (Peter Grootenboer); (2) Theoretical Model of Analysis of Rate Problems in Algebra (Jose Guzman, Nadine Bednarz and Fernando Hitt); (3) Locating Fractions on…

  14. Canadian Mathematics Education Study Group = Groupe Canadien d'Etude en Didactique des Mathematiques. Proceedings of the Annual Meeting (25th, Edmonton, Alberta, Canada, May 25-29, 2001).

    ERIC Educational Resources Information Center

    Simmt, Elaine, Ed.; Davis, Brent, Ed.

    This document contains the proceedings of the 2001 annual meeting of the Canadian Mathematics Education Study Group (CMESG) held at the University of Alberta, May 25-39, 2000. The proceedings consist of two plenary lectures, four working groups, five topic sessions, new Ph.D. reports, an AD Hoc Session, and panel discussions. Papers include: (1)…

  15. Research in Science Education, 1994. Selected Refereed Papers from the Annual Conference of the Australasian Science Education Research Association (25th, Hobart, Tasmania, Australia, July 10-13, 1994).

    ERIC Educational Resources Information Center

    Gardner, Paul L., Ed.

    1994-01-01

    This volume contains 41 papers, 10 abstracts/research notes, and an after-dinner speech "The Book of Genesis and the Chronicles of the People of ASERA (Australasian Science Education Research Association). Paper titles include: "Improving students' understanding of carbohydrate metabolism in first-year Biochemistry at tertiary level"; "Students'…

  16. A concurrent resolution congratulating the Navy and the current and former officers and crew of the U.S.S. Enterprise (CVN 65) on completion of the 25th and final deployment of the vessel.

    THOMAS, 112th Congress

    Sen. Warner, Mark R. [D-VA

    2012-12-19

    12/19/2012 Referred to the Committee on Armed Services. (text of measure as introduced: CR S8206) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  17. The Ecology, the Environment, and the Evolution of Technical Communication. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (25th, Lewes, Delaware, October 15-17, 1998).

    ERIC Educational Resources Information Center

    Council for Programs in Technical and Scientific Communication.

    This proceedings presents 40 papers delivered at the 1998 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into sections on the Ecology of Technology; Environmental Shifts; and Evolving Perspectives. Representative papers in the proceedings include: "Mixing Oil and…

  18. Academic Libraries and the Sciences: Assuring Successful Scholarship. Proceedings of a Program in Celebration of the 25th Anniversary of the University of California, Irvine and in Anticipation of Its New Science Library (Irvine, California, April 9, 1991).

    ERIC Educational Resources Information Center

    California Univ., Irvine.

    This document on successful scholarship in the sciences contains a keynote paper followed by six faculty responses. The keynote paper, delivered by Phillip Abelson of the American Association for the Advancement of Science (AAAS), is entitled "Assuring Successful Scholarship in the Sciences." Some of the factors likely to influence the nature of…

  19. Biomarkers predictive of venous thromboembolism in patients with newly diagnosed high-grade gliomas

    PubMed Central

    Thaler, Johannes; Ay, Cihan; Kaider, Alexandra; Reitter, Eva-Maria; Haselböck, Johanna; Mannhalter, Christine; Zielinski, Christoph; Marosi, Christine; Pabinger, Ingrid

    2014-01-01

    Background High-grade gliomas (HGGs) are among the most prothrombotic of malignancies. Methods We performed a prospective study to investigate 11 potential biomarkers for prediction of venous thromboembolism (VTE) in newly diagnosed HGG patients who had undergone a neurosurgical intervention. In addition, we tested 2 VTE risk assessment models (RAMs). The strongest predictors of VTE, which were identified by statistical forward selection, were used for the first RAM. The parameters used for the second RAM were both predictive of VTE and available in routine clinical practice. Results One hundred forty-one HGG patients were included in this study, and 24 (17%) of them developed VTE during follow-up. An association with the risk of future VTE was found for the following parameters: leukocyte count, platelet count, sP-selectin, prothrombin-fragment 1 + 2, FVIII activity, and D-dimer. The first RAM included low platelet count (<25th percentile of the study population) and elevated sP-selectin (≥75th percentile). The cumulative VTE probability after 12 months was 9.7% for score 0 (n = 76), 18.9% for score 1 (n = 59), and 83.3% for score 2 (n = 6). The second RAM included low platelet count (<25th percentile), elevated leukocyte count, and elevated D-dimer (≥75th percentile). The probability of VTE was 3.3% for score 0 (n = 63), 23.0% for score 1 (n = 53), and 37.7% for score 2 (n = 22) or score 3 (n = 3). Conclusions We identified biomarkers suitable for assessing the VTE risk in newly diagnosed HGG patients. The application of 2 RAMs allowed identification of patients at high risk of developing VTE. We could also define patients at low risk of VTE, who would most probably not benefit from extended primary thromboprophylaxis. PMID:24987133

  20. Iodine status among pregnant women after mandatory salt iodisation.

    PubMed

    Anaforoğlu, İ; Algün, E; İnceçayır, Ö; Topbaş, M; Erdoğan, M F

    2016-02-14

    I is essential for thyroid hormone synthesis and neurological development. Various changes occur in thyroid hormone metabolism during pregnancy and I requirements increase significantly. The purpose of this study was to investigate I status among pregnant women in Trabzon, formerly a severely I-deficient area but shown to have become I sufficient following mandatory iodisation of table salt based on monitoring studies among school-age children (SAC) in the area. A total of 864 healthy pregnant women with a median age of 28 (25th-75th percentile 17-47) years participated in the study. None of them were using I-containing supplement. All of them were screened for use of iodised salt, obstetric history, thyroid function tests and urinary I concentrations (UIC), and thyroid ultrasonography was performed. Median UIC was 102 (25th-75th percentile=62-143) μg/l. Median UIC of the patients according to trimesters were 122 µg/l at the 1st, 97 µg/l at the 2nd and 87 µg/l at the 3rd trimester. UIC in the 1st trimester was higher compared with the 2nd and 3rd trimesters (P<0·017). Nodules were present in 17·7% of women (n 153). The rate of iodised salt usage among pregnant women was 90·7%. Our study demonstrates that, although the I status among SAC has been rectified, I deficiency (ID) is still prevalent among pregnant women. Current knowledge is in favour of I supplementation in this group. Until the effects of maternal I supplementation in mild ID have been clarified by large-scale prospective controlled trials, pregnant women living in borderline defficient and I-sufficient areas, such as Trabzon city, should receive 100-200 µg/d of I-containing supplements in addition to iodised salt. PMID:26596695

  1. Clinical characteristics of 53 dogs with Doppler-derived evidence of pulmonary hypertension: 1992-1996.

    PubMed

    Johnson, L; Boon, J; Orton, E C

    1999-01-01

    Pulmonary hypertension occurs as a primary or secondary disorder of the pulmonary vasculature. Doppler echocardiography provides a noninvasive tool for the estimation of pulmonary arterial pressure when tricuspid regurgitation or pulmonic insufficiency is present. The cardiology database at Colorado State University was reviewed, and echocardiographic records from cases diagnosed with pulmonary hypertension were evaluated. Application of the modified Bernoulli equation to the maximal instantaneous velocity of a right-sided regurgitant jet provided evidence of pulmonary hypertension in 53 dogs over a 4-year period. Tricuspid regurgitant velocity > or = 2.8 m/second or pulmonic insufficiency velocity > or = 2.2 m/second was considered abnormal and indicative of pulmonary hypertension. Tricuspid regurgitant gradients in 51 dogs ranged from 32 to 145 mm Hg (mean, 63.0 mm Hg; median, 57.0 mm Hg; 25th-75th percentiles, 45.2-76.5 mm Hg). Pulmonic insufficiency gradients in 8 dogs ranged from 20 to 100 mm Hg (mean, 59.5 mm Hg; median, 61.5 mm Hg; 25th-75th percentiles, 32.0-84.5 mm Hg). Affected dogs ranged in age from 2 months to 16 years. Clinical signs were characteristic of cardiopulmonary disease, but a relatively high frequency of syncope was noted (12 of 53 dogs, 23%). Pulmonary hypertension was probably due to increased pulmonary vascular resistance in 23 dogs, pulmonary overcirculation in 2 dogs, and pulmonary venous hypertension in 23 dogs. Five dogs lacked a clinically recognizable cardiopulmonary cause of pulmonary vascular disease. Our results suggest that pulmonary hypertension can occur as a complication of commonly encountered cardiopulmonary diseases, and that Doppler echocardiography can facilitate recognition of this condition. PMID:10499728

  2. Iodized Salt in Cambodia: Trends from 2008 to 2014

    PubMed Central

    Laillou, Arnaud; Mam, Borath; Oeurn, Sam; Chea, Chantum

    2015-01-01

    Though the consequences of nutritional iodine deficiency have been known for a long time, in Cambodia its elimination has only become a priority in the last 18 years. The Royal Government of Cambodia initiated the National Sub-Committee for Control of Iodine Deficiency Disorders in 1996 to fight this problem. Using three different surveys providing information across all provinces, we examined the compliance of salt iodization in Cambodia over the last 6 years. Salt samples from the 24 provinces were collect at the household level in 2008 (n = 566) and 2011 (n = 1275) and at the market level in 2014 (n = 1862) and analysed through a wavelength spectrophotometer for iodine content. According to the samples collected, the median iodine content significantly dropped from 22 mg/kg (25th/75th percentile: 2/37 mg/kg) in 2011 to 0 mg/kg in 2014 (25th/75th percentile: 0/8.9 mg/kg) (p < 0.001). The proportion of non-iodized salt within our collected salt drastically increased from 22% in 2011 to 62% in 2014 (p < 0.001). Since the international organizations ceased to support the procurement of iodine, the prevalence of salt compliant with the Cambodian declined within our samples. To date, the current levels of iodine added to tested salt are unsatisfactory as 92% of those salts do not meet the government requirements (99.6% of the coarse salt and 82.4% of the fine salt). This inappropriate iodization could illustrate the lack of periodic monitoring and enforcement from government entities. Therefore, government quality inspection should be reinforced to reduce the quantity of salt not meeting the national requirement. PMID:26035245

  3. Proteomic Analysis of Early Mid-Trimester Amniotic Fluid Does Not Predict Spontaneous Preterm Delivery

    PubMed Central

    Lenco, Juraj; Vajrychova, Marie; Link, Marek; Tambor, Vojtech; Liman, Victor; Bullarbo, Maria; Nilsson, Staffan; Tsiartas, Panagiotis; Cobo, Teresa; Kacerovsky, Marian; Jacobsson, Bo

    2016-01-01

    Objective The aim of this study was to identify early proteomic biomarkers of spontaneous preterm delivery (PTD) in mid-trimester amniotic fluid from asymptomatic women. Methods This is a case-cohort study. Amniotic fluid from mid-trimester genetic amniocentesis (14–19 weeks of gestation) was collected from 2008 to 2011. The analysis was conducted in 24 healthy women with subsequent spontaneous PTD (cases) and 40 randomly selected healthy women delivering at term (controls). An exploratory phase with proteomics analysis of pooled samples was followed by a verification phase with ELISA of individual case and control samples. Results The median (interquartile range (IQR: 25th; 75th percentiles) gestational age at delivery was 35+5 (33+6–36+6) weeks in women with spontaneous PTD and 40+0 (39+1–40+5) weeks in women who delivered at term. In the exploratory phase, the most pronounced differences were found in C-reactive protein (CRP) levels, that were approximately two-fold higher in the pooled case samples than in the pooled control samples. However, we could not verify these differences with ELISA. The median (25th; 75th IQR) CRP level was 95.2 ng/mL (64.3; 163.5) in women with spontaneous PTD and 86.0 ng/mL (51.2; 145.8) in women delivering at term (p = 0.37; t-test). Conclusions Proteomic analysis with mass spectrometry of mid-trimester amniotic fluid suggests CRP as a potential marker of spontaneous preterm delivery, but this prognostic potential was not verified with ELISA. PMID:27214132

  4. Validity, reliability, and sensitivity-to-change properties of the psoriatic arthritis screening and evaluation questionnaire

    PubMed Central

    Husni, M. Elaine; Holt, Elizabeth W.; Tyler, Stephanie; Qureshi, Abrar A.

    2010-01-01

    Psoriatic arthritis (PsA) is an inflammatory arthritis associated with irreversible joint damage in a subset of individuals. There is a need to screen early for this condition to prevent damage. To meet this need, we have developed the psoriatic arthritis screening and evaluation (PASE) questionnaire. The 15-item PASE questionnaire was administered to 190 individuals with either psoriasis or PsA. The PASE questionnaire was readministered to a subset of individuals with PsA in order to assess test–retest reliability and sensitivity-to-change. Receiver operator curves were constructed to optimize sensitivity and specificity for the diagnosis of PsA. Of the 190 participating in the study, 19.5% (37/191) participants were diagnosed with PsA. PASE total scores ranged from 15 to 74 (possible range, 15–75). The PsA group had a median Total score of 51 (25th and 75th percentile 44 and 57), and non-PsA group had a median total score of 34 (25th and 75th percentile 21 and 49) (p < 0.001). A PASE total score of 44 was able to distinguish PsA from non-PsA participants with 76% sensitivity and 76% specificity. Furthermore, 13 of the 15 items demonstrated significant test–retest reliability as assessed by Pearson correlation coefficient (r ≥ 0.5). PASE was sensitive-to-change with therapy; PASE scores were significantly lower for PsA individuals after systemic therapy (p < 0.034). The PASE questionnaire is a valid and reliable tool to screen for active PsA among individuals with psoriasis. PASE scores may be used as a marker of therapeutic response. PMID:19603175

  5. Percentile Ranking and Citation Impact of a Large Cohort of NHLBI-funded Cardiovascular R01 Grants

    PubMed Central

    Danthi, Narasimhan; Wu, Colin O.; Shi, Peibei; Lauer, Michael

    2014-01-01

    Rationale Funding decisions for cardiovascular R01 grant applications at NHLBI largely hinge on percentile rankings. It is not known whether this approach enables the highest impact science. Objective To conduct an observational analysis of percentile rankings and bibliometric outcomes for a contemporary set of funded NHLBI cardiovascular R01 grants. Methods and results We identified 1492 investigator-initiated de novo R01 grant applications that were funded between 2001 and 2008, and followed their progress for linked publications and citations to those publications. Our co-primary endpoints were citations received per million dollars of funding, citations obtained within 2-years of publication, and 2-year citations for each grant’s maximally cited paper. In 7654 grant-years of funding that generated $3004 million of total NIH awards, the portfolio yielded 16,793 publications that appeared between 2001 and 2012 (median per grant 8, 25th and 75th percentiles 4 and 14, range 0 – 123), which received 2,224,255 citations (median per grant 1048, 25th and 75th percentiles 492 and 1,932, range 0 – 16,295). We found no association between percentile ranking and citation metrics; the absence of association persisted even after accounting for calendar time, grant duration, number of grants acknowledged per paper, number of authors per paper, early investigator status, human versus non-human focus, and institutional funding. An exploratory machine-learning analysis suggested that grants with the very best percentile rankings did yield more maximally cited papers. Conclusions In a large cohort of NHLBI-funded cardiovascular R01 grants, we were unable to find a monotonic association between better percentile ranking and higher scientific impact as assessed by citation metrics. PMID:24406983

  6. [Improvement of outcomes by primary treatment for temporomandibular disorders].

    PubMed

    Aoyama, Shigeru; Kino, Koji; Iwaki, Hiroshi; Amagasa, Teruo

    2008-10-01

    The aim of this study was to survey the current state of the temporomandibular joint disorder treatment in our clinic and to confirm the therapeutic outcomes. The subjects in this study were recruited from among the patients with temporomandibular disorders who attended the Temporomandibular Disorder Special Clinic, Department of Oral Surgery, Hitachi Yokohama Hospital during one year period from February 2007 to January 2008. A total of 100 consecutive outpatients diagnosed with temporomandibular disorders were selected for the study. Pain intensity and the degree to which daily function was limited before and after treatment were evaluated using the Visual Analogue Scale (VAS). The Beck Depression Inventory-II (BDI-II) score was evaluated simultaneously, and the correlation with changes in symptom was evaluated. The median (25th, 75th percentiles) of pain intensity (VAS value) before treated was 45 (25.0, 65.0) and the degree of limitation of daily function (VAS value) was 15 (0.0, 50.0). The median (25th, 75th percentiles) of pain intensity at 4 weeks after was 10 (0.0, 30.0), and significantly lower than that before treatment (p = 0.000). The degree of limitation of daily function was 0 (0.0, 10.0), also significantly lower than that before treatment (p = 0.000). The BDI-II score decreased from 8 (2.0, 11.8) before treatment to 5 (2.0, 11.0, p = 0.024) and showed no significant correlation with the improvement in outcomes by primary treatment for temporomandibular disorders. PMID:19044015

  7. Seasonal Analysis of Combined Climate Indices in Serbia

    NASA Astrophysics Data System (ADS)

    Arsenovic, Pavle; Tosic, Ivana; Unkasevic, Miroslava

    2014-05-01

    Joint distributions of two weather variables, such as temperature and precipitation, better reflect the weather conditions than temperature or precipitation statistics taken separately (Beniston 2010). Hence, the seasonal analysis of combined climate indices in Serbia is presented using Warm/Dry (WD), Warm/Wet (WW), Cold/Dry (CD) and Cold/Wet (CW) days. The present study is based on the collection of the daily mean temperatures and precipitation at seven stations from the observational network of the Serbian Meteorological Service during the period 1961 - 2010. Day is conceived as warm (cold) if the daily mean temperature is greater (less) than the 75th (25th) percentile. Day is considered as dry (wet) if the daily precipitation sums are below the 25th percentile (higher than the 75th percentile). Temperature percentiles were calculated for each day in a year, while precipitation percentiles were calculated for each season. It is obtained that the number of WW days is small for all seasons. An increasing tendency of WD and decreasing tendencies of CD and CW are observed. Correlation between the combined climatic indices and the North Atlantic Oscillation (NAO) are examined. It was found that the connection existed between the NAO index and CW and WD during the winter, CD during the autumn and WD during the summer. Our results are in accordance with previous results of Beniston (2009), who revealed a systematic change at nine European cities in the course of the 20th century with significant declines in the frequency of occurrence of the "cold" modes and a sharp rise in that of the "warm" modes. Beniston, M., 2009: Trends in joint quantiles of temperature and precipitation in Europe since 1901 and projected for 2100. Geophysical Research Letters, 36, L07707 Beniston, M., 2010: Impacts of climatic change on water and associated economic activities in the Swiss Alps. Journal of Hydrology, doi:10.1016/j.jhydrol.2010.06.046

  8. Association of Fusobacterium nucleatum infection with colorectal cancer in Chinese patients

    PubMed Central

    Li, Yu-Yuan; Ge, Quan-Xing; Cao, Jie; Zhou, Yong-Jian; Du, Yan-Lei; Shen, Bo; Wan, Yu-Jui Yvonne; Nie, Yu-Qiang

    2016-01-01

    AIM: To investigate Fusobacterium nucleatum (F. nucleatum) abundance in colorectal cancer (CRC) tissues and its association with CRC invasiveness in Chinese patients. METHODS: The resected cancer and adjacent normal tissues (10 cm beyond cancer margins) from 101 consecutive patients with CRC were collected. Fluorescent quantitative polymerase chain reaction (FQ-PCR) was applied to detect F. nucleatum in CRC and normal tissues. The difference of F. nucleatum abundance between cancer and normal tissues and the relationship of F. nucleatum abundance with clinical variables were evaluated. Fluorescence in situ hybridization (FISH) analysis was performed on 22 CRC tissues with the highest F. nucleatum abundance by FQ-PCR testing to confirm FQ-PCR results. RESULTS: The median abundance of F. nucleatum in CRC tissues [0.242 (0.178-0.276)] was significantly higher than that in normal controls [0.050 (0.023-0.067)] (P < 0.001). F. nucleatum was over-represented in 88/101 (87.1%) CRC samples. The abundance of F. nucleatum determined by 2-ΔCT was significantly greater in tumor samples [0.242 (0.178, 0.276)] than in normal controls [0.050 (0.023, 0.067)] (P < 0.001). The frequency of patients with lymph node metastases was higher in the over-abundance group [52/88 (59.1%)] than in the under-abundance group [0/13 (0%)] (P < 0.005). No significant association of F. nucleatum with other clinico-pathological variables was observed (P > 0.05). FISH analysis also found more F. nucleatum in CRC than in normal tissues (median number 6, 25th 3, 75th 10 vs 2, 25th 1, 75th 5) (P < 0.01). CONCLUSION: F. nucleatum was enriched in CRC tissues and associated with CRC development and metastasis. PMID:27004000

  9. Perception Versus Actual Performance in Timely Tissue Plasminogen Activation Administration in the Management of Acute Ischemic Stroke

    PubMed Central

    Lin, Cheryl B; Cox, Margueritte; Olson, DaiWai M; Britz, Gavin W; Constable, Mark; Fonarow, Gregg C; Schwamm, Lee; Peterson, Eric D; Shah, Bimal R

    2015-01-01

    Background Timely thrombolytic therapy can improve stroke outcomes. Nevertheless, the ability of US hospitals to meet guidelines for intravenous tissue plasminogen activator (tPA) remains suboptimal. What is unclear is whether hospitals accurately perceive their rate of tPA “door-to-needle” (DTN) time within 60 minutes and how DTN rates compare across different hospitals. Methods and Results DTN performance was defined by the percentage of treated patients who received tPA within 60 minutes of arrival. Telephone surveys were obtained from staff at 141 Get With The Guidelines hospitals, representing top, middle, and lowDTN performance. Less than one-third (29.1%) of staff accurately identified their DTN performance. Among middle- and low-performing hospitals (n=92), 56 sites (60.9%) overestimated their performance; 42% of middle performers and 85% of low performers overestimated their performance. Sites that overestimated tended to have lower annual volumes of tPA administration (median 8.4 patients [25th to 75th percentile 5.9 to 11.8] versus 10.2 patients [25th to 75th percentile 8.2 to 17.3], P=0.047), smaller percentages of eligible patients receiving tPA (84.7% versus 89.8%, P=0.008), and smaller percentages of DTN ≤60 minutes among treated patients (10.6% versus 16.6%, P=0.002). Conclusions Hospitals often overestimate their ability to deliver timely tPA to treated patients. Our findings indicate the need to routinely provide comparative provider performance rates as a key step to improving the quality of acute stroke care. PMID:26201547

  10. Applicability of Two Universally Accepted Mixed Dentition Analysis on a Sample from Southeastern Region of Andhra Pradesh, India

    PubMed Central

    Shobha, MB; AJS, Sai; Manoj, KMG; Srideevi, E; Sridhar, M; Pratap, GMJS

    2016-01-01

    Background: Most of the universally accepted mixed dentition analyses are based on the data derived from northwestern European descent. However, the accuracy of these methods when applied to different ethnic population is questionable. Aim: The present study is aimed to evaluate the applicability of Tanaka and Johnston (TJ) and Moyers (50th and 75th percentile) mixed dentition analysis in a sample from south-eastern region of Andhra Pradesh, India. Subjects and Methods: Study models were prepared from a sample of 100 patients (50 males and 50 females) in the age range of 13-15 years. The mesio-distal dimension of the teeth was measured using a Digital Vernier calipers. The actual values of permanent canine and premolars on the casts were compared with the predicted values from TJ and Moyers analysis. The values derived from this study were statistically analyzed using SPSS version 17.0 (IBM, Chicago, USA). Pearson's coefficients were used to evaluate the correlations between the groups of teeth. Results: Overestimated values were noticed in males and females of both arches with TJ equation; Males showed no significant difference at Moyers 50th percentile (50/100), in both the arches where as females showed higher values in mandibular arch and underestimated values in maxillary arch. At Moyers 75th percentile, overestimated values were noticed in males for both the arches whereas in females lesser values were observed. Conclusion: As the values showed significant deviation from TJ and Moyers both at 50 and 75 percentile, its applicability to the present population is limited. So, new regression equations were derived. PMID:27398250

  11. Temporal and spatial trends of chloride and sodium in groundwater in New Hampshire, 1960–2011

    USGS Publications Warehouse

    Medalie, Laura

    2012-01-01

    Data on concentrations of chloride and sodium in groundwater in New Hampshire were assembled from various State and Federal agencies and organized into a database. This report provides documentation of many assumptions and limitations of disparate data that were collected to meet wide-ranging objectives and investigates temporal and spatial trends of the data. Data summaries presented in this report and analyses performed for this study needed to take into account the 27 percent of chloride and 5 percent of sodium data that were censored (less than a reporting limit) at multiple reporting limits that systematically decreased over time. Throughout New Hampshire, median concentrations of chloride were significantly greater during 2000-2011 than in every decade since the 1970s, and median concentrations of sodium were significantly greater during 2000-2011 than during the 1990s. Results of summary statistics showed that the 50th, 75th, and 90th percentiles of the median concentrations of chloride and sodium by source (well) from Rockingham and Strafford counties were the highest in the State; and the 75th and 90th percentiles from Carroll, Coos, and Grafton counties were the lowest. Large increases in median concentrations of chloride and sodium for individual wells after 1995 compared with concentrations for years before were found in parts of Belknap and Rockingham counties and in small clusters within Carroll, Hillsborough, and Merrimack counties.

  12. Effect of Menopausal Status on Carotid Intima-Media Thickness and Presence of Carotid Plaque in Chinese Women Generation Population

    PubMed Central

    Zhou, Yong; Wang, Dandan; Yang, Xin; Wang, Anxin; Gao, Xiang; Guo, Yuming; Wu, Shouling; Zhao, Xingquan

    2015-01-01

    Menopause is an important physiological stage in women's life. The potential association of menopause with carotid intima-media thickness as well as with occurrence and stability of carotid plaque in Chinese female population is unclear. We conducted a population-based, cross-sectional study by recruiting 2,131 participants aged above 40 years from northeast of China. Carotid intima-media thickness (CIMT), presence of carotid plaque and its stability were evaluated by carotid duplex sonography. Among the participants, 1,133 (53.2%) were identified to be postmenopausal. After adjusting for potential confounding factors, presence of CIMT at 50th- 75th and ≥75th percentiles, carotid plaque and its unstable status were found to be significantly associated with the postmenopausal status (P < 0.001). When matched the participants by age, post-menopausal status was still associated with a higher risk of having unstable plaque. Moreover, our data show that postmenopausal status is a risk factor for intracranial arterial stenosis when compared with premenopausal status in the univariate analysis (OR = 1.314, P = 0.043), and such relationship is lost when the confounding factors are adjusted (OR = 0.828, P = 0.225). In conclusion, the vascular risk factors increase as the menopausal status changes. Compared with premenopausal status, postmenopausal status is associated with higher morbidity of CIMT, carotid plaque and its unstable status. PMID:25627797

  13. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XVI: Miscellaneous Studies.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Miscellaneous Studies section of the proceedings contains the following 16 papers: "Mickey Mouse and Bugs Bunny: Iconography of Two Corporate Stars" (William A. Mikulak); "We Know Who You Are: A Niche Communications Explication and Model" (Jana Frederick-Collins); "The Ways They Get Their Stories: Is Utilitarianism the Best Moral Theory for…

  14. Assessment System for Special Education Students Exempted from the Texas Assessment Program. A Report Submitted to the Governor, Lieutenant Governor, Speaker of the House, and the 75th Texas Legislature.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin.

    The Texas Education Code requires the Commissioner of Education to develop and propose a system for evaluating the progress of students eligible for exemption from the statewide assessment program under current law. This report summarizes the proposed system for special education students. It includes proposed changes to the assessment and…

  15. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part II: Journalism History, Section B.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section B of the Journalism History section of the proceedings contains the following nine papers: "Weep into Silence/Cries of Rage: Bitter Divisions in Hawaii's Japanese Press" (Tom Brislin); "Viewing the Newspaper as International: The First International Organization of Journalists Debates News Copyright 1894-1898" (Ulf Jonas Bjork); "The…

  16. Political Science's Responsibility to the Community: A Promise Fulfilled? Anniversary Sessions of the Department of Political Science, University of Illinois (75th, Urbana-Champaign, Illinois, November 20-21, 1981). The Edmund James James Lecture.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Dept. of Political Science.

    This report contains the keynote speech, the panel discussions, and questions (with responses) from the audience for each of two major sessions on the responsibility of political science to the community. The focus of the first session was academic political science and public service. The keynote speaker was William N. Cassella. Panelists were…

  17. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part III: Media History.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Media History section of the proceedings contains the following nine papers: "'This Is a Test': The Evolution of the Emergency Broadcast System" (Larry G. Burkum); "Radio Homemaker Programming: Old Time Radio's Ingredient for Attracting Women Listeners" (J. Steven Smethers and Lee Jolliffe); "Her Amplified Voice: Gender, War Propaganda and…

  18. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part IX: Media and Technology.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Media and Technology section of these proceedings contains the following six papers: "The Effects of Tabular and Graphical Display Formats on Time Spent Processing Statistics" (James D. Kelly); "Program Choice in a Broadband Environment" (Steven S. Wildman and Nancy Y. Lee); "Visual Crosstabs: A Technique for Enriching Information Graphics"…

  19. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part I: Journalism History, Section A.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section A of the Journalism History section of the proceedings contains the following 10 papers: "Mixed Messages in a Progressive Newspaper: The Milwaukee Journal and Woman Suffrage, 1911-1912" (Elizabeth Burt); "The Search for Unity: The Importance of the Black Press in the Emigration/Colonization Issues of the 1800s" (Bernell E. Tripp);…

  20. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part IV: Media and Law, Section A.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section A of the Media and Law section of the proceedings contains the following nine papers: "RICO and the First Amendment: Racketeering Laws Threaten Free Expression" (Matthew D. Bunker and others); "Press Coverage of the Federal Appellate Courts: Technology and a Shared Notion of Newsworthiness" (Rebekah V. Bromley); "The Evolution of Illinois…

  1. A resolution recognizing the 75th anniversary of the founding of Ducks Unlimited, Incorporated, the achievements of the organization in habitat conservation, and the support of the organization for the waterfowling heritage of the United States.

    THOMAS, 112th Congress

    Sen. Wicker, Roger F. [R-MS

    2012-04-19

    04/19/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2557; text as passed Senate: CR S2557; text of measure as introduced: CR S2553) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  2. Investing in Human Capital. Leadership for the Challenges of the 21st Century. Edited Proceedings of the Institute of International Education Forum (75th, New York, New York, October 27, 1994).

    ERIC Educational Resources Information Center

    Institute of International Education, New York, NY.

    These proceedings highlight the Institute for International Education's forum on the implications of the emergence of a global economy and the worldwide communications revolutions for international education and training. Over 200 individuals from the corporate, foundation, government, academic, and diplomatic communities participated in the…

  3. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part VIII: Mass Media Effects.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Mass Media Effects section of the proceedings contains the following eight papers: "The Spiral of Static: A Multivariate Analysis of a Public Opinion Theory Applied to Perception of Radio Station Popularity" (Terry Wedel and Tony Rimmer); "More Than Just Talk: Uses, Gratifications and the Telephone" (Garrett J. O'Keefe and Barbara K.…

  4. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part X: Health, Science, and the Environment.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Health, Science, and the Environment section of these proceedings contains the following seven papers: "Columbus, Mars, and the Changing Images and Ideologies of Exploration: A Critical Examination" (Lin Bin and August T. Horvath); "Prime Time TV Portrayals of Sex, 'Safe Sex' and AIDS: A Longitudinal Analysis" (Dennis T. Lowry and Jon A.…

  5. S.Res.430 — 112th Congress (2011-2012) A resolution recognizing the 75th anniversary of the founding of Ducks Unlimited, Incorporated, the achievements of the organization in habitat conservation, and the support of the organization for...

    THOMAS, 112th Congress

    Sen. Wicker, Roger F. [R-MS

    2012-04-19

    04/19/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2557; text as passed Senate: CR S2557; text of measure as introduced: CR S2553) (All Actions)

  6. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part V: Media and Law, Section B.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section B of the Media and Law section of the proceedings contains the following nine papers: "The Professional Person as Libel Plaintiff: Reexamination of the Public Figure Doctrine" (Harry W. Stonecipher and Don Sneed); "The Anti-Federalists and Taxation under the Free Press Clause of the First Amendment" (Brad Thompson); "Independent State…

  7. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XII: Foreign and International Media.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The International Media section of the proceedings contains the following 13 papers: "Text and Context: A Case Study of International News Discourse" (Shujen Wang); "The Future of Public Service Broadcasting in Japan and the U.K.: A Comparative Analysis" (Roya Akhavan-Majid); "Reinventing Freedom of the Press: The Search for a Post-Soviet Model in…

  8. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part VI: Politics and Mass Media.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Politics and Mass Media section of the proceedings contains the following eight papers: "Politics and the War on Drugs: Patterns of News Coverage" (Lisa Brockmeier); "The Challenge of Bearing Witness in Political Reporting: Making the Public Conversational Partners" (Karon Reinboth Speckman); "The Concrete-Avoidance Model: Media, Public…

  9. Massive obesity in a migrant Samoan population.

    PubMed Central

    Pawson, I G; Janes, C

    1981-01-01

    Peoples of the Pacific Islands tend to become overweight when they migrate or are exposed to modernization in situ. Recent evidence suggests that Samoans are particularly susceptible, exhibiting a high prevalence of obesity and hypertension following migration to Hawaii. We report the preliminary results of a survey of height, weight, blood pressure, and fasting plasma glucose (FPG) among an urbanized Samoan community the the San Francisco Bay Area. Although the participants' average height fell between the 25th and 50th percentile of the US population, about one-half our sample exceeded the 95th percentile for weight. The extreme overweight was accompanied by elevated blood pressure and, in females, by elevated FPG. The massive adult weight of migrants from the Pacific Islands carries serious public health implications for areas that support large migrant communities. PMID:7212139

  10. Maternal but not fetal FADS gene variants modify the association between maternal long-chain PUFA intake in pregnancy and birth weight.

    PubMed

    Moltó-Puigmartí, Carolina; van Dongen, Martien C J M; Dagnelie, Pieter C; Plat, Jogchum; Mensink, Ronald P; Tan, Frans E S; Heinrich, Joachim; Thijs, Carel

    2014-09-01

    Several studies have shown a positive association between maternal fish intake in pregnancy and pregnancy duration and child birth weight (BW), probably due to fish n-3 (ω-3) long-chain polyunsaturated fatty acids (LC-PUFAs). n-3 LC-PUFAs can also be synthesized endogenously, and their synthesis depends on single nucleotide polymorphisms (SNPs) in the fatty acid desaturase (FADS) gene encoding for FADS. We assessed the associations of maternal docosahexaenoic acid (DHA) intake in pregnancy with pregnancy duration and BW and investigated whether these associations are modified by maternal or fetal FADS SNP genotypes. We hypothesized that we would find stronger associations in minor allele homozygous mothers or fetuses due to their lower n-3 LC-PUFA endogenous synthesis and hence higher dependence on dietary supply. Data on maternal diet, pregnancy duration, and BW were available for 2622 mother-child pairs from the KOALA (Kind, Ouders en gezondheid: Aandacht voor Leefstijl en Aanleg) Birth Cohort Study. The rs174556 FADS SNP was genotyped in 1516 mothers and 1515 children. Associations and gene-diet interactions were tested with linear regression adjusting for potential confounders, including intake of other PUFAs. Women at the 75th percentile of DHA intake had 0.7-d longer pregnancies (P = 0.016) and 28-g heavier infants (P = 0.039) than did women at the 25th percentile of intake. Associations with arachidonic acid intake were of the same order but in the opposite direction. Mothers who were homozygous for the minor allele had 2-d shorter pregnancies (P = 0.035) and infants who were nearly 140 g lighter (P = 0.006) than did mothers who were major allele homozygotes. Post hoc analyses revealed that they had higher prepregnancy BMI (P = 0.020). Among the women homozygous for the minor allele, those at the 75th percentile of DHA intake had 226-g heavier infants than those at the 25th percentile of intake (P = 0.030), whereas DHA intake was not significantly

  11. Highly Specific Detection of Myostatin Prodomain by an Immunoradiometric Sandwich Assay in Serum of Healthy Individuals and Patients

    PubMed Central

    Widera, Christian; Gottlieb, Jens; Vogel, Arndt; Schmidt, Sebastian; Brandes, Gudrun; Heuft, Hans-Gert; Lichtinghagen, Ralf; Kempf, Tibor; Wollert, Kai C.; Bauersachs, Johann; Heineke, Joerg

    2013-01-01

    Background Myostatin is a muscle derived factor that functions as a negative regulator of skeletal muscle growth. Induction of myostatin expression was observed in rodent models of muscle wasting and in cachectic patients with cancer or pulmonary disease. Therefore, there is an increasing interest to use serum myostatin as a biomarker. Methods We established an immunoradiometric sandwich assay (IRMA), which uses a commercially available chicken polyclonal, affinity purified antibody directed against human myostatin prodomain. We determined the serum concentrations of myostatin prodomain in 249 healthy individuals as well as 169 patients with heart failure, 53 patients with cancer and 44 patients with chronic pulmonary disease. Results The IRMA had a detection limit of 0.7ng/ml, an intraassay imprecision of ≤14.1% and an interassay imprecision of ≤ 18.9%. The specificity of our assay was demonstrated by size exclusion chromatography, detection of myostatin by Western-blotting and a SMAD-dependent transcriptional-reporter assay in the signal-rich serum fractions, as well as lack of interference by unspecific substances like albumin, hemoglobin or lipids. Myostatin prodomain was stable at room temperature and resistant to freeze-thaw cycles. Apparently healthy individuals over the age of 55 had a median myostatin prodomain serum concentration of 3.9ng/ml (25th-75th percentiles, 2-7ng/ml) and we could not detect increased levels in patients with stable chronic heart failure or cancer related weight loss. In contrast, we found strongly elevated concentrations of myostatin prodomain (median 26.9ng/ml, 25th-75th percentiles, 7-100ng/ml) in the serum of underweight patients with chronic pulmonary disease. Conclusions We established a highly specific IRMA for the quantification of myostatin prodomain concentration in human serum. Our assay could be useful to study myostatin as a biomarker for example in patients with chronic pulmonary disease, as we detected highly

  12. The Impact of Different Regimes in Estimating the Effects of Aerosols on Clouds. A Case Study over the Baltic Sea Countries.

    NASA Astrophysics Data System (ADS)

    Saponaro, G.

    2015-12-01

    (both AOD and AI). Separated aerosol settings (AI/AOD <25th percentile versus AI/AOD > 75th percentile) provide information regarding the saturation effect. Meteorological environments. LTS determines an unstable thermodynamic environment (LTS <25th percentile) and a stable one ( LTS >75th percentile).

  13. Assessment of lead in cosmetic products.

    PubMed

    Al-Saleh, Iman; Al-Enazi, Sami; Shinwari, Neptune

    2009-07-01

    There have been a number of recent reports in the media and on the internet about the presence of lead in brand-names lipsticks. This has drawn our attention to assess the safety of various cheap brands of cosmetics sold at 2-riyals stores in Saudi market that are imported from countries where safety regulations are poorly enforced as well as they lack perfect conditions for manufacturing. Lead contents were determined in 26 and eight different brands of lipsticks and eye shadows using the Zeeman atomic absorption spectrophotometer coupled to graphite tube atomizer after an acid digestion procedure. Lead was detected in all the studied samples. The median (25th-75th percentile) lead content in 72 lipsticks samples was 0.73 (0.49-1.793) PPM wet wt. in the range of 0.27-3760 PPM wet wt. There were four brands of lipsticks with lead content above the FDA lead limit as impurities in color additives (20 PPM). The FDA does not set a limit for lead in lipstick. Three of them were extremely high points and considered outliers. The median (25th-75th percentile) lead contents in pressed powder eye shadow was 1.38 (0.944-1.854) PPM wet wt. (n=22) in the range of 0.42-58.7 PPM wet wt. One brand was above 20 PPM the US FDA's lead limit as impurities. The overall results indicate that lead in lipsticks and eye shadows are below the FDA lead limit as impurities and, thus, probably have no significant toxicological effects. Nevertheless, few brands had lead content above 20 PPM that might put consumers at the risk of lead poisoning. Lead is a cumulative, and applying lead-containing cosmetics several times a day or every day, can potentially add up to significant exposure levels. Pregnant and nursing mothers are vulnerable population because lead passes through placenta and human milk and affect fetus or infant's developments. Our findings call for an immediate mandatory regular testing program to check lead and other toxic metals in lipsticks and other cosmetic products imported

  14. Effect of 10% fluoride on the remineralization of dentin in situ

    PubMed Central

    BIZHANG, Mozhgan; KALETA-KRAGT, Sabine; SINGH-HÜSGEN, Preeti; ALTENBURGER, Markus Jörg; ZIMMER, Stefan

    2015-01-01

    ABSTRACT Objective The purpose of this randomized, cross-over, in situ study was to determine the remineralization of demineralized dentin specimens after the application of a 10% fluoride (F-) or a 1% chlorhexidine–1% thymol (CHX–thymol) varnish. Material and Methods Twelve individuals without current caries activity wore removable appliances in the lower jaw for a period of four weeks. Each appliance contained four human demineralized dentin specimens fixed on the buccal aspects. The dentin specimens were obtained from the cervical regions of extracted human third molars. After demineralization, half the surface of each specimen was covered with a nail varnish to serve as the reference surface. The dentin specimens were randomly assigned to one of the three groups: F-, CHX–thymol, and control (no treatment). Before the first treatment period and between the others, there were washout periods of one week. After each treatment phase, the changes in mineral content (vol% µm) and the lesion depths (µm) of the dentin slabs were determined by transverse microradiography (TMR). Data analysis was accomplished by the Kruskal-Wallis test and the Mann-Whitney U test (p<0.05). Results The medians (25th/75th percentile) of integrated mineral loss were 312.70 (203.0-628.7) for chlorhexidine varnish, 309.5 (109.8-665.8) for fluoride varnish, and -346.9 (-128.7 - -596.0) for the control group. The medians (25th/75th percentile) of lesion depth were 13.6 (5.7-34.5) for chlorhexidine varnish, 16.5 (5.6-38.1) for fluoride varnish, and -14.2 (-4.5- -32.9) for the control group. Use of the 10% F- or 1% CHX–1% thymol varnishes resulted in significantly decreased mineral loss and lesion depth in dentin when compared with the control group. There were no statistically significant differences among the test groups. Conclusions Within the limitations of this study, the results suggest that the effect of the treatment of demineralized dentin with 10% F- or 1% CHX–1% thymol is

  15. Reliability of Single-Use PEEP-Valves Attached to Self-Inflating Bags during Manual Ventilation of Neonates – An In Vitro Study

    PubMed Central

    Hartung, Julia C.; Wilitzki, Silke; Thio-Lluch, Marta; te Pas, Arjan B.; Schmalisch, Gerd; Roehr, Charles C.

    2016-01-01

    Introduction International resuscitation guidelines suggest to use positive end-expiratory pressure (PEEP) during manual ventilation of neonates. Aim of our study was to test the reliability of self-inflating bags (SIB) with single-use PEEP valves regarding PEEP delivery and the effect of different peak inflation pressures (PIP) and ventilation rates (VR) on the delivered PEEP. Methods Ten new single-use PEEP valves from 5 manufacturers were tested by ventilating an intubated 1kg neonatal manikin containing a lung model with a SIB that was actuated by an electromechanical plunger device. Standard settings: PIP 20cmH2O, VR 60/min, flow 8L/min. PEEP settings of 5 and 10cmH2O were studied. A second test was conducted with settings of PIP 40cmH2O and VR 40/min. The delivered PEEP was measured by a respiratory function monitor (CO2SMO+). Results Valves from one manufacturer delivered no relevant PEEP and were excluded. The remaining valves showed a continuous decay of the delivered pressure during expiration. The median (25th and 75th percentile) delivered PEEP with standard settings was 3.4(2.7–3.8)cmH2O when set to 5cmH2O and 6.1(4.9–7.1)cmH2O when set to 10cmH2O. Increasing the PIP from 20 to 40 cmH2O led to a median (25th and 75th percentile) decrease in PEEP to 2.3(1.8–2.7)cmH2O and 4.3(3.2–4.8)cmH2O; changing VR from 60 to 40/min led to a PEEP decrease to 2.8(2.1–3.3)cmH2O and 5.0(3.5–6.2)cmH2O for both PEEP settings. Conclusion Single-use PEEP valves do not reliably deliver the set PEEP. PIP and VR have an effect on the delivered PEEP. Operators should be aware of these limitations when manually ventilating neonates. PMID:26914209

  16. Effect of 10% fluoride on the remineralization of dentin in situ.

    PubMed

    Bizhang, Mozhgan; Kaleta-Kragt, Sabine; Singh-Hüsgen, Preeti; Altenburger, Markus Jörg; Zimmer, Stefan

    2015-01-01

    Objective The purpose of this randomized, cross-over, in situ study was to determine the remineralization of demineralized dentin specimens after the application of a 10% fluoride (F-) or a 1% chlorhexidine-1% thymol (CHX-thymol) varnish. Material and Methods Twelve individuals without current caries activity wore removable appliances in the lower jaw for a period of four weeks. Each appliance contained four human demineralized dentin specimens fixed on the buccal aspects. The dentin specimens were obtained from the cervical regions of extracted human third molars. After demineralization, half the surface of each specimen was covered with a nail varnish to serve as the reference surface. The dentin specimens were randomly assigned to one of the three groups: F-, CHX-thymol, and control (no treatment). Before the first treatment period and between the others, there were washout periods of one week. After each treatment phase, the changes in mineral content (vol% µm) and the lesion depths (µm) of the dentin slabs were determined by transverse microradiography (TMR). Data analysis was accomplished by the Kruskal-Wallis test and the Mann-Whitney U test (p<0.05). Results The medians (25th/75th percentile) of integrated mineral loss were 312.70 (203.0-628.7) for chlorhexidine varnish, 309.5 (109.8-665.8) for fluoride varnish, and -346.9 (-128.7 - -596.0) for the control group. The medians (25th/75th percentile) of lesion depth were 13.6 (5.7-34.5) for chlorhexidine varnish, 16.5 (5.6-38.1) for fluoride varnish, and -14.2 (-4.5- -32.9) for the control group. Use of the 10% F- or 1% CHX-1% thymol varnishes resulted in significantly decreased mineral loss and lesion depth in dentin when compared with the control group. There were no statistically significant differences among the test groups. Conclusions Within the limitations of this study, the results suggest that the effect of the treatment of demineralized dentin with 10% F- or 1% CHX-1% thymol is better than without

  17. Turkish PASE: Turkish Version of the Psoriatic Arthritis Screening and Evaluation Questionnaire

    PubMed Central

    Oyur, Kadir Berat; Hatemi, Gülen; Asma, Ali; Kutlubay, Zekayi; Bulut, Nurgül; Serdaroğlu, Server; Tüzün, Yalçın

    2014-01-01

    Background Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis and causes irreversible joint damage, unless detected early and treated with systemic drugs. Objective There is no reliable tool for screening PsA among Turkish psoriasis patients. Therefore, we aimed to validate the psoriatic arthritis screening and evaluation (PASE) questionnaire in the Turkish. Methods A 15-item Turkish PASE questionnaire was administered to 122 consecutive psoriasis patients who visited our dermatology clinic for routine evaluations. Then, the patients were evaluated for PsA by a rheumatologist who was blinded to the results of the questionnaire. Results Among the 113 patients who participated in the study, 11.5% (13 of 113) had a diagnosis of PsA. The Turkish PASE total scores ranged from 15 to 67 (possible range, 15~75). The median total score was 49 (25th and 75th percentile, 36 and 50) for the PsA group and 35 (25th and 75th percentile, 27 and 42) for the non-PsA group. The median total score of the PsA group was significantly higher than that of the non-PsA group (p=0.33). The Turkish PASE total score of 44 distinguished PsA from non-PsA participants, with 62% sensitivity and 76% specificity. For further analysis of each question, we counted the responses according to symptoms (positive for "agree" and "strongly agree" and negative for "disagree" and "strongly disagree"), and the sensitivity ranged from 23% (third question of the functions subscale) to 77% (second question of the symptoms subscale, first and fifth questions of the functions subscale) and the specificity ranged from 51% (second question of the symptoms subscale) to 87% (fourth question of the functions subscale). No relation was found between the PASI scores and the presence (p=0.899) or absence (p=0.941) of PsA, as well as between the PASI and PASE scores of each patient (p=0.961). Conclusion Thirteen of the 15 items demonstrated significant test-retest reliability as assessed with

  18. Risk Assessment of Arsenic in Rice Cereal and Other Dietary Sources for Infants and Toddlers in the U.S.

    PubMed

    Shibata, Tomoyuki; Meng, Can; Umoren, Josephine; West, Heidi

    2016-01-01

    Currently, there are no set standards or quantitative guidelines available in the U.S. for arsenic levels in rice cereal, one of the most common first solid foods for infants. The objective of this study was to evaluate whether the detected levels of inorganic arsenic (Asi) in rice cereal in the U.S. market are safe for consumption by infants and toddlers. A risk assessment was conducted based on literature reviews of the reported Asi in rice cereal from the U.S. Food and Drug Administration's (FDA) survey and the recommended daily intake of rice cereal by body weight, for infants and toddlers between four and 24 months old. As a part of risk management, a maximum contaminant level (MCL) for Asi in rice cereal was computed considering overall exposure sources including drinking water, infant formula, and other infant solid foods. Hazard quotients (HQs) for acute and chronic exposures were calculated based on the U.S. Agency for Toxic Substances and Disease Registry's (ATSDR) Minimal Risk Level (MRL)acute (5.0 × 10(-3) mg/kg/day) and MRLchronic (3.0 × 10(-4) mg/kg/day). A cancer slope or potency factor of 1.5 mg/kg/day was used to predict an incremental lifetime cancer risk (ILCR). Exposure assessment showed that the largest source of Asi for infants and toddlers between four and 24 months old was rice cereal (55%), followed by other infant solid food (19%), and drinking water (18%). Infant formula was the smallest source of Asi for babies (9%) at the 50th percentile based on Monte Carlo simulations. While HQacute were consistently below 1.0, HQchronic at the 50 and 75th percentiles exceeded 1.0 for both rice cereal and total sources. ILCR ranged from 10(-6) (50th) to 10(-5) (75th percentile). MCLs for Asi in rice cereal ranged from 0.0 (chronic) to 0.4 mg/kg (acute exposures). PMID:27023581

  19. Risk Assessment of Arsenic in Rice Cereal and Other Dietary Sources for Infants and Toddlers in the U.S.

    PubMed Central

    Shibata, Tomoyuki; Meng, Can; Umoren, Josephine; West, Heidi

    2016-01-01

    Currently, there are no set standards or quantitative guidelines available in the U.S. for arsenic levels in rice cereal, one of the most common first solid foods for infants. The objective of this study was to evaluate whether the detected levels of inorganic arsenic (Asi) in rice cereal in the U.S. market are safe for consumption by infants and toddlers. A risk assessment was conducted based on literature reviews of the reported Asi in rice cereal from the U.S. Food and Drug Administration’s (FDA) survey and the recommended daily intake of rice cereal by body weight, for infants and toddlers between four and 24 months old. As a part of risk management, a maximum contaminant level (MCL) for Asi in rice cereal was computed considering overall exposure sources including drinking water, infant formula, and other infant solid foods. Hazard quotients (HQs) for acute and chronic exposures were calculated based on the U.S. Agency for Toxic Substances and Disease Registry’s (ATSDR) Minimal Risk Level (MRL)acute (5.0 × 10−3 mg/kg/day) and MRLchronic (3.0 × 10−4 mg/kg/day). A cancer slope or potency factor of 1.5 mg/kg/day was used to predict an incremental lifetime cancer risk (ILCR). Exposure assessment showed that the largest source of Asi for infants and toddlers between four and 24 months old was rice cereal (55%), followed by other infant solid food (19%), and drinking water (18%). Infant formula was the smallest source of Asi for babies (9%) at the 50th percentile based on Monte Carlo simulations. While HQacute were consistently below 1.0, HQchronic at the 50 and 75th percentiles exceeded 1.0 for both rice cereal and total sources. ILCR ranged from 10−6 (50th) to 10−5 (75th percentile). MCLs for Asi in rice cereal ranged from 0.0 (chronic) to 0.4 mg/kg (acute exposures). PMID:27023581

  20. Intraventricular twin fetuses in fetu.

    PubMed

    Huddle, Lauren N; Fuller, Christine; Powell, Tiffany; Hiemenga, Judith A; Yan, Jia; Deuell, Brian; Lyders, Eric M; Bodurtha, Joann N; Papenhausen, Peter R; Jackson-Cook, Colleen K; Pandya, Arti; Jaworski, Margie; Tye, Gary W; Ritter, Ann M

    2012-01-01

    The authors report a rare case of multiple intracranial fetuses in fetu, fulfilling Willis' traditional criteria, which include an axial and appendicular skeleton with surrounding organized tissue. This case was ascertained from studies of a full-term female neonate who presented with ventriculomegaly. A CT scan showed intracranial calcifications that were suggestive of an axial skeleton. Her birth weight was 3.176 kg (50th-75th percentile), length was 52 cm (90th percentile), head circumference was 35 cm (50th-75th percentile), and Apgar scores were 7 and 8 at 1 and 5 minutes, respectively. Prenatal ultrasonography studies performed at 12 weeks and 5 days, and 19 weeks and 6 days revealed normal findings. A 37-week prenatal ultrasonography study showed ventriculomegaly and obstructive hydrocephalus, with a possible intracranial teratoma. Cranial imaging at birth with ultrasonography, CT and MR imaging, and MR angiography demonstrated 2 complex intraventricular masses with cystic, solid, and bony elements. A craniotomy with resection of the masses was performed at 3 months of age. The infant survived and is now 12 months old with some developmental progress. Two axial skeletons, with accompanying rib cage and extremities, including well-formed feet and toes, were noted. Both anencephalic structures had skin with hair, fat, skeletal and smooth muscle, and bony structures with bone marrow and focal areas of calcification. Multiple viscera were present and included thymus, bowel, stomach, salivary gland, kidney, adrenal gland, lung, and presumed adnexal structures. A diagnosis of fetuses in fetu was rendered. Chromosomal studies of the child and tissue from the 2 fetuses in fetu showed normal female karyotypes. A single nucleotide polymorphism array analysis from the proband infant and tissue from the 2 identified fetuses in fetu appeared to be genetically identical. These results are consistent with a monozygotic twin embryonic origin of the fetus in fetu tissue

  1. A resolution recognizing the 50th anniversary of the date of enactment of the law that created real estate investment trusts (REITs) and gave millions of Americans new investment opportunities that helped them build a solid foundation for retirement and has contributed to the overall strength of the economy of the United States.

    THOMAS, 112th Congress

    Sen. Isakson, Johnny [R-GA

    2011-02-17

    02/17/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S923-924; text as passed Senate: CR S923-924; text of measure as introduced: CR S912-913) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  2. A bill to award posthumously a Congressional Gold Medal to Addie Mae Collins, Denise McNair, Carole Robertson, and Cynthia Wesley, in recognition of the 50th anniversary of the bombing of the Sixteenth Street Baptist Church, where the 4 little Black girls lost their lives, which served as a catalyst for the Civil Rights Movement.

    THOMAS, 113th Congress

    Sen. Shelby, Richard C. [R-AL

    2013-01-30

    01/30/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Notes: For further action, see H.R.360, which became Public Law 113-11 on 5/24/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  3. A resolution recognizing the 50th anniversary of "Smoking and Health: Report of the Advisory Committee to the Surgeon General of the United States" and the significant progress in reducing the public health burden of tobacco use, and supporting an end to tobacco-related death and disease.

    THOMAS, 113th Congress

    Sen. Blumenthal, Richard [D-CT

    2014-01-13

    01/13/2014 Referred to the Committee on Health, Education, Labor, and Pensions. (text of measure as introduced: CR S292) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. S.Res.60 — 112th Congress (2011-2012) A resolution recognizing the 50th anniversary of the date of enactment of the law that created real estate investment trusts (REITs) and gave millions of Americans new investment opportunities that...

    THOMAS, 112th Congress

    Sen. Isakson, Johnny [R-GA

    2011-02-17

    02/17/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S923-924; text as passed Senate: CR S923-924; text of measure as introduced: CR S912-913) (All Actions)

  5. A resolution congratulating the 1963 men's basketball team of Loyola University Chicago on its induction into the National Collegiate Basketball Hall of Fame, the 50th anniversary of the team's Division I National Collegiate Athletic Association men's basketball championship, and the team's historic NCAA tournament game against Mississippi State University.

    THOMAS, 113th Congress

    Sen. Kirk, Mark Steven [R-IL

    2013-07-10

    07/10/2013 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S5622) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. Ivsite, Na3H(SO4)2, a new mineral from volcanic exhalations of fumaroles of the Fissure Tolbachik Eruption of the 50th Anniversary of the Institute of Volcanology and Seismology, Far East Branch, Russian Academy of Sciences

    NASA Astrophysics Data System (ADS)

    Filatov, S. K.; Karpov, G. A.; Shablinskii, A. P.; Krivovichev, S. V.; Vergasova, L. P.; Antonov, A. V.

    2016-06-01

    Fine-granular (<0.1 mm) flattened colorless transparent crystals of ivsite form white aggregates. The empirical formula (Na2.793Cu0.056)2.849HS2.016O8 is close to the ideal Na3H(SO4)2. The structure was refined up to R = 0.040. Ivsite has a monoclinic symmetry, P21/ c, a = 8.655(1) Å, b = 9.652(1) Å, c = 9.147(1) Å, β = 108.76(1)°, V = 723.61(1) Å3, Z = 4. Na atoms occur at six- and seven-fold sites (NaO6 and NaO7); S atoms, in isolated SO4 tetrahedrons; these polyhedrons form a three-dimensional framework. The diagnostic lines of powder diffraction patterns ( d[Å]- I- hkl) are 4.010-53-12-1, 3.949-87-012, 3.768-100-210, 3.610-21-20-2, 3.022-22-031, 2.891-42-22-2, 2.764-49-31-1, and 2.732-70-13-1.

  7. A resolution recognizing the 50th anniversary of the Great Alaska Earthquake, which struck the State of Alaska at 5:36 p.m. on Good Friday, March 27, 1964, honoring those who lost their lives in the Great Alaska Earthquake and associated tsunamis, and expressing continued support for research on earthquake and tsunami prediction and mitigation strategies.

    THOMAS, 113th Congress

    Sen. Murkowski, Lisa [R-AK

    2014-03-27

    03/27/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S1800-1803; text as passed Senate: CR S1831) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  8. Perfluorooctanoate Exposure and Major Birth Defects

    PubMed Central

    Stein, Cheryl R.; Savitz, David A.; Elston, Beth; Thorpe, Phoebe G.; Gilboa, Suzanne M.

    2014-01-01

    Perfluorooctanoate (PFOA) is detectable in umbilical cord blood and amniotic fluid. Some toxicological findings suggest that perfluoroalkyl substances may be teratogenic. Using data from the C8 Health Project, a 2005 – 2006 survey in a Mid-Ohio Valley community exposed to PFOA through contaminated drinking water, we examined the association between estimated prenatal PFOA concentration and maternally reported birth defects (n=325) among 10,262 live singleton or multiple births from 1990 – 2006. Logistic regression models accounted for siblings using generalized estimating equations. There was generally no association between estimated PFOA concentration and birth defects, with the possible exception of brain defects, where the odds ratio adjusted for year of conception was 2.6 (95% confidence interval 1.3 – 5.1) for an increase in estimated PFOA exposure from the 25th to 75th percentile. This estimate, however, was based on 13 cases and may represent a chance finding. Further investigation of this potential association may be warranted. PMID:24803403

  9. Radio Point Sources Toward Galaxy Clusters at 30 GHz

    NASA Technical Reports Server (NTRS)

    Coble, K.; Carlstrom, J. E.; Bonamente, M.; Dawson, K.; Holzapfel, W.; Joy, M.; LaRoque, S.; Reese, E. D.

    2006-01-01

    Extra-galactic point sources are a significant contaminant in cosmic microwave background and Sunyaev-Zel'dovich effect experiments. Deep interferometric observations with the BIMA and OVRO arrays are used to characterize the spatial, spectral, and flux distributions of radio point sources toward galaxy clusters at 28.5 GHz. We compute counts of mJy point source fluxes from 90 fields centered on known massive galaxy clusters and 8 non-cluster fields. Counts in the non-cluster fields are consistent with extrapolations from the results of other surveys. We also compute counts towards clusters as a function of luminosity in three redshift bins out to z = 1.0 and see no clear evidence for evolution with redshift. We compute spectral indices of mJy sources in cluster fields between 1.4 and 28.5 GHz. The distribution is skewed, with a median spectral index of 0.76 and 25th and 75th percentiles of 0.55 and 0.95, respectively. This is steeper than the spectral indices of brighter field point sources measured by other surveys.

  10. Epidemiology and impact of Fasciola hepatica exposure in high-yielding dairy herds

    PubMed Central

    Howell, Alison; Baylis, Matthew; Smith, Rob; Pinchbeck, Gina; Williams, Diana

    2015-01-01

    The liver fluke Fasciola hepatica is a trematode parasite with a worldwide distribution and is the cause of important production losses in the dairy industry. The aim of this observational study was to assess the prevalence of exposure to F. hepatica in a group of high yielding dairy herds, to determine the risk factors and investigate their associations with production and fertility parameters. Bulk milk tank samples from 606 herds that supply a single retailer with liquid milk were tested with an antibody ELISA for F. hepatica. Multivariable linear regression was used to investigate the effect of farm management and environmental risk factors on F. hepatica exposure. Higher rainfall, grazing boggy pasture, presence of beef cattle on farm, access to a stream or pond and smaller herd size were associated with an increased risk of exposure. Univariable regression was used to look for associations between fluke exposure and production-related variables including milk yield, composition, somatic cell count and calving index. Although causation cannot be assumed, a significant (p < 0.001) negative association was seen between F. hepatica exposure and estimated milk yield at the herd level, representing a 15% decrease in yield for an increase in F. hepatica exposure from the 25th to the 75th percentile. This remained significant when fertility, farm management and environmental factors were controlled for. No associations were found between F. hepatica exposure and any of the other production, disease or fertility variables. PMID:26093971

  11. The effects of weather conditions on measles incidence in Guangzhou, Southern China

    PubMed Central

    Yang, Qiongying; Fu, Chuanxi; Wang, Naizhen; Dong, Zhiqiang; Hu, Wensui; Wang, Ming

    2014-01-01

    Background: Few studies were conducted to examine the effects of weather conditions on the incidence of measles. Methods: We used a distributed lag non-linear model (DLNM) to analyze the relationship between meteorological factors and measles incidence in Guangzhou, China. Results: Nonlinear effects of temperature and relative humidity on measles incidence were observed. The relative risk (RR) for the measles incidence associated with the 75th percentile of mean temperature (27.9 °C) relative to the median of mean temperature (24.7 °C) was 1.00 (0.86,1.16) for lags 0–10 days. The RR for the measles incidence associated with the 25th percentile of relative humidity (64%) relative to the median of relative humidity (73%) was 1.36 (1.01,1.82) for lags 0–30 days. The wet effects and dry effects were larger in females than in males. The wet effects were generally increased with ages. Significantly negative effects of cold spells on measles incidence were observed. Conclusion: Both hot and cold temperatures result in decreases in the incidence of measles, and low relative humidity is a risk factor of measles morbidity. An increased number of measles cases might occur before and after a cold spell. Our findings highlight the need to pay more attention to the weather transformation and improve the immunity of susceptible population for measles elimination. Catch-up vaccination campaigns should be initiated among young adults. PMID:24509358

  12. Health Impact in New York City During the Northeastern Blackout of 2003

    PubMed Central

    Lin, Shao; Fletcher, Barbara A.; Luo, Ming; Chinery, Robert; Hwang, Syni-An

    2011-01-01

    Objective This study assessed the health effects of the 2003 Northeastern blackout, the largest one in history, on mortality and hospital admissions due to respiratory, cardiovascular, and renal diseases in New York City (NYC), and compared the disease patterns and sociodemographic profiles of cases during the blackout with those on control days. Method We investigated the effects of the blackout on health using incidence rate ratios to compare the disease on blackout days (August 14 and 15, 2003) with those on normal and comparably hot days (controls). Normal days were defined as summer days (June–August) between the 25th and 75th percentiles of maximum temperature during 1991–2004. Comparably hot days were days with maximum temperatures in the same range as that of the blackout days. We evaluated the interactive effects of demographics and the blackout using a case-only design. Results We found that mortality and respiratory hospital admissions in NYC increased significantly (two- to eightfold) during the blackout, but cardiovascular and renal hospitalizations did not. The most striking increases occurred among elderly, female, and chronic bronchitis admissions. We identified stronger effects during the blackout than on comparably hot days. In contrast to the pattern observed for comparably hot days, higher socioeconomic status groups were more likely to be hospitalized during the blackout. Conclusions This study suggests that power outages may have important health impacts, even stronger than the effects of heat alone. The findings provide some direction for future emergency planning and public health preparedness. PMID:21553667

  13. Urinary strontium and the risk of breast cancer: A case-control study in Guangzhou, China

    SciTech Connect

    Chen, Li-Juan; Tang, Lu-Ying; He, Jian-Rong; Su, Yi; Cen, Yu-Ling; Yu, Dan-Dan; Wu, Bang-Hua; Lin, Ying; Chen, Wei-Qing; Song, Er-Wei; Ren, Ze-Fang

    2012-01-15

    Strontium has been widely used in industries like electronic and pharmacy. It has a carcinogenic potential, however, and no study has been conducted to evaluate its effects on cancer risk. The aim of this study was to explore the possible association between strontium and breast cancer risk in a case-control study including 240 incident invasive breast cancer patients and 246 age-matched controls. We measured the urinary concentrations of strontium by inductively coupled plasma mass spectrometry, and conducted face-to-face interviews to obtain information on potential breast cancer risk factors. Multivariable analysis was used to estimate the association. Creatinine-adjusted levels [median (25th, 75th) {mu}g/g] of strontium were 155.59 (99.05, 230.70) in the breast cancer patients and 119.62 (81.97, 163.76) in the controls. Women in the highest tertile of strontium showed 124% increased risk of breast cancer, when compared with those in the lowest tertile after adjustment for the potential risk factors [OR (95% CI): 2.24 (1.42-3.81)]. This association was particularly strong for HER2 positive breast cancer [OR (95% CI): 10.92 (3.53-33.77)], and only occurred among premenopausal women. These results suggest a potential role of strontium in the development of breast cancer and urge further studies on the environmental contamination and the physiological and pathological mechanisms of strontium.

  14. Hospital Costs and Inpatient Mortality among Children Undergoing Surgery for Congenital Heart Disease

    PubMed Central

    Romley, John A; Chen, Alex Y; Goldman, Dana P; Williams, Roberta

    2014-01-01

    Objective To determine the association between hospital costs and risk-adjusted inpatient mortality among children undergoing surgery for congenital heart disease (CHD) in U.S. acute-care hospitals. Data Sources/Study Settings Retrospective cohort study of 35,446 children in 2003, 2006, and 2009 Kids' Inpatient Database (KID). Study Design Cross-sectional logistic regression of risk-adjusted inpatient mortality and hospital costs, adjusting for a variety of patient-, hospital-, and community-level confounders. Data Collection/Extraction Methods We identified relevant discharges in the KID using the AHRQ Pediatric Quality Indicator for pediatric heart surgery mortality, and linked these records to hospital characteristics from American Hospital Association Surveys and community characteristics from the Census. Principal Findings Children undergoing CHD surgery in higher cost hospitals had lower risk-adjusted inpatient mortality (p = .002). An increase from the 25th percentile of treatment costs to the 75th percentile was associated with a 13.6 percent reduction in risk-adjusted mortality. Conclusions Greater hospital costs are associated with lower risk-adjusted inpatient mortality for children undergoing CHD surgery. The specific mechanisms by which greater costs improve mortality merit further exploration. PMID:24138064

  15. Nationwide variation in the effects of temperature on infectious gastroenteritis incidence in Japan

    PubMed Central

    Onozuka, Daisuke; Hagihara, Akihito

    2015-01-01

    Although several studies have investigated the effects of temperature on the incidence of infectious gastrointestinal disease in a single city or region, few have investigated variations in this association using nationwide data. We obtained weekly data, gathered between 2000 and 2012, pertaining to infectious gastroenteritis cases and weather variability in all 47 Japanese prefectures. A two-stage analysis was used to assess the nonlinear and delayed relationship between temperature and morbidity. In the first stage, a Poisson regression allowing for overdispersion in a distributed lag nonlinear model was used to estimate the prefecture-specific effects of temperature on morbidity. In the second stage, a multivariate meta-analysis was applied to pool estimates at the national level. The pooled overall relative risk (RR) was highest in the 59.9th percentile of temperature (RR, 1.08; 95% CI: 1.01, 1.15). Meta-analysis results also indicated that the estimated pooled RR at lower temperatures (25th percentile) began immediately but did not persist, whereas an identical estimate at a higher temperature (75th percentile) was delayed but persisted for several weeks. Our results suggest that public health strategies aimed at controlling temperature-related infectious gastroenteritis may be more effective when tailored according to region-specific weather conditions. PMID:26255569

  16. Do Physicians Change Prescription Practice in Response to Financial Incentives?

    PubMed

    Park, Sylvia; Han, Euna

    2016-07-01

    We assessed the impact on physician prescription behaviors of an outpatient prescription incentive program providing financial rewards to primary care physicians for saving prescription costs in South Korea. A 10% sample of clinics (N = 1,625) was randomly selected from all clinics in the National Health Insurance claims database for the years 2009-2012, and all claims with the primary diagnosis of peptic ulcer or gastro-esophageal reflux diseases were extracted from those clinics' data. A clinic-level random-effects model was used. After the program, clinics in general medicine showed a lower prescription rate (by 0.8 percentage points), lower number of medicines prescribed (by 0.02), lower prescription duration (by 0.15 days), and lower drug expenditure per claim (by 740 won). Small clinics on the <25th percentile of a regional sum of monthly drug expenditure had shorter prescription duration (by 0.76 days), while large clinics on the ≥75th percentile and clinics in group practice had a higher prescription rate (by 1.5 and 2.5 percentage points, respectively) and a higher number of medicines prescribed (by 0.03 for group practice only) after the program. The outpatient prescription incentive program worked as intended only in certain subgroup clinics for the target medicines. PMID:27193920

  17. Using Simulation to Better Understand the Effects of Aging on Driver Visibility.

    PubMed

    Kajaks, Tara; Vrkljan, Brenda; MacDermid, Joy; Godwin, Allison

    2016-06-01

    This proof-of-concept pilot study explored virtual simulation methodology to quantify blind-spot line-of-sight using avatars derived from an older driver database (n = 100). Siemens Jack software simulated the blind spots of eight older driver avatars (four female). The male and female avatars were scaled to be small (25th percentile) and large (75th percentile) based on the height distribution for the older driver database, and had either "normal" (65 degrees) or "abnormal" (50 degrees) neck range of motion (ROM). A virtual model of a Volkswagen Beetle was used to illustrate left and right blind-spot line-of-sight for each avatar. Average line-of-sight between blind spots was 22.3 per cent and 10.4 per cent in the "normal" and "abnormal" rotational neck ROM conditions, respectively. Older drivers with functional impairments affecting neck ROM are more likely to have problems with left blind-spot line-of-sight. Findings are discussed with regard to vehicle design considerations for older adults. PMID:27067866

  18. Epidemiology and impact of Fasciola hepatica exposure in high-yielding dairy herds.

    PubMed

    Howell, Alison; Baylis, Matthew; Smith, Rob; Pinchbeck, Gina; Williams, Diana

    2015-09-01

    The liver fluke Fasciola hepatica is a trematode parasite with a worldwide distribution and is the cause of important production losses in the dairy industry. The aim of this observational study was to assess the prevalence of exposure to F. hepatica in a group of high yielding dairy herds, to determine the risk factors and investigate their associations with production and fertility parameters. Bulk milk tank samples from 606 herds that supply a single retailer with liquid milk were tested with an antibody ELISA for F. hepatica. Multivariable linear regression was used to investigate the effect of farm management and environmental risk factors on F. hepatica exposure. Higher rainfall, grazing boggy pasture, presence of beef cattle on farm, access to a stream or pond and smaller herd size were associated with an increased risk of exposure. Univariable regression was used to look for associations between fluke exposure and production-related variables including milk yield, composition, somatic cell count and calving index. Although causation cannot be assumed, a significant (p<0.001) negative association was seen between F. hepatica exposure and estimated milk yield at the herd level, representing a 15% decrease in yield for an increase in F. hepatica exposure from the 25th to the 75th percentile. This remained significant when fertility, farm management and environmental factors were controlled for. No associations were found between F. hepatica exposure and any of the other production, disease or fertility variables. PMID:26093971

  19. Readability of the Written Study Information in Pediatric Research in France

    PubMed Central

    Ménoni, Véronique; Lucas, Noël; Leforestier, Jean-François; Doz, François; Chatellier, Gilles; Jacqz-Aigain, Evelyne; Giraud, Carole; Tréluyer, Jean-Marc; Chappuy, Hélène

    2011-01-01

    Background The aim was to evaluate the readability of research information leaflets (RIL) for minors asked to participate in biomedical research studies and to assess the factors influencing this readability. Methods and Findings All the pediatric protocols from three French pediatric clinical research units were included (N = 104). Three criteria were used to evaluate readability: length of the text, Flesch's readability score and presence of illustrations. We compared the readability of RIL to texts specifically written for children (school textbooks, school exams or extracts from literary works). We assessed the effect of protocol characteristics on readability. The RIL had a median length of 608 words [350 words, 25th percentile; 1005 words, 75th percentile], corresponding to two pages. The readability of the RIL, with a median Flesch score of 40 [30; 47], was much poorer than that of pediatric reference texts, with a Flesch score of 67 [60; 73]. A small proportion of RIL (13/91; 14%) were illustrated. The RIL were longer (p<0.001), more readable (p<0.001) and more likely to be illustrated (p<0.009) for industrial than for institutional sponsors. Conclusion Researchers should routinely compute the reading ease of study information sheets and make greater efforts to improve the readability of written documents for potential participants. PMID:21494689

  20. How much is a 'pea-sized amount'? A study of dentifrice dosing by parents in three countries.

    PubMed

    Creeth, Jonathan; Bosma, Mary Lynn; Govier, Katherine

    2013-12-01

    To provide optimal fluoride effectiveness against caries while minimising risk of negative effects from excessive ingestion from toothbrushing, the fluoride dose delivered at each occasion is critical. This is particularly important for young children, so using a 'pea-sized amount' is generally recommended. However, there appears little guidance regarding what this means in practice, although it has been indicated to be 0.25 g. This study investigated, using conventional toothpastes and toothbrushes in Germany, the USA and the UK, how much toothpaste parents dispense for their 3- to 6 year-old children, and their interpretation of a 'pea-sized' amount of toothpaste. When asked to dispense the amount they would normally for their child, the majority of parents dosed substantially more than 0.25 g; in Germany, all parents over-dispensed. The amount dispensed varied widely: those parents at the 75th centile dispensed approximately twice the amount dispensed by those at the 25th centile, irrespective of country. When asked to dispense a pea-sized amount, the mean amount dosed decreased significantly in all countries. In the USA, electric toothbrush users dispensed about 0.1 g more than manual toothbrush users. While over-dispensing of fluoride toothpaste remains a cause for concern, it may be argued that the general recommendation to use a pea-sized amount of toothpaste generally works well in practice to balance the conflicting demands of risk and benefit from toothbrushing with fluoride toothpaste in young children. PMID:24283281

  1. A model validation study of the washout/rainout contribution of sulfate and nitrate in wet deposition compared with precipitation chemistry data in Japan

    NASA Astrophysics Data System (ADS)

    Kajino, Mizuo; Aikawa, Masahide

    2015-09-01

    We simulated washout/rainout ratios of non-sea-salt (nss)-SO42- and NO3- using a chemical transport model and compared the estimates with precipitation measurements sampled at 0.5/1 mm intervals at sites located in Kobe (urban), Toyo-oka (suburban), and Tamba (rural) cities, Japan. The 25th and 75th percentile range of the simulated washout contributions was 30-70%. The simulated washout contribution range of NO3- (40-70%) was greater than that of nss-SO42 - (30-60%). There was good agreement between the simulated and observed values, and the observed washout contribution of NO3- was also greater than that of SO42-. The simulated washout contribution range was higher (60-75%) in emission source regions and lower (40-55%) in downwind areas. The wet deposition process is one of the key causes of uncertainty in chemical transport modeling. Comparing model results with such high-frequency precipitation chemistry data has been extremely rare. Thus the current study is providing useful information for evaluating and improving wet deposition modeling and for the better understanding of the wet deposition mechanism.

  2. Determining shapes and dimensions of dental arches for the use of straight-wire arches in lingual technique

    PubMed Central

    Kairalla, Silvana Allegrini; Scuzzo, Giuseppe; Triviño, Tarcila; Velasco, Leandro; Lombardo, Luca; Paranhos, Luiz Renato

    2014-01-01

    INTRODUCTION: This study aims to determine the shape and dimension of dental arches from a lingual perspective, and determine shape and size of a straight archwire used for lingual Orthodontics. METHODS: The study sample comprised 70 Caucasian Brazilian individuals with normal occlusion and at least four of Andrew's six keys. Maxillary and mandibular dental casts were digitized (3D) and the images were analyzed by Delcam Power SHAPET 2010 software. Landmarks on the lingual surface of teeth were selected and 14 measurements were calculated to determine the shape and size of dental arches. RESULTS: Shapiro-Wilk test determined small arch shape by means of 25th percentile (P25%) - an average percentile for the medium arch; and a large one determined by means of 75th percentile (P75%). T-test revealed differences between males and females in the size of 12 dental arches. CONCLUSION: The straight-wire arch shape used in the lingual straight wire technique is a parabolic-shaped arch, slightly flattened on its anterior portion. Due to similarity among dental arch sizes shown by males and females, a more simplified diagram chart was designed. PMID:25715725

  3. Cyanide in bronchoalveolar lavage is not diagnostic for Pseudomonas aeruginosa in children with cystic fibrosis.

    PubMed

    Stutz, M D; Gangell, C L; Berry, L J; Garratt, L W; Sheil, B; Sly, P D

    2011-03-01

    Early detection of the cyanobacterium Pseudomonas aeruginosa in the lungs of young children with cystic fibrosis (CF) is considered the key to delaying chronic pulmonary disease. We investigated whether cyanide in bronchoalveolar lavage (BAL) fluid could be used as an early diagnostic biomarker of infection. Cyanide was measured in 226 BAL samples (36 P. aeruginosa infected) obtained from 96 infants and young children with CF participating in an early surveillance programme involving annual BAL. Cyanide was detected in 97.2% of P. aeruginosa infected and 60.5% of uninfected samples. Cyanide concentrations were significantly higher in BALs infected with P. aeruginosa (median (25th-75th percentile) 27.3 (22.1-33.3) μM) than those which were not (17.2 (7.85-23.0) μM, p<0.001). The best sensitivity, specificity, positive and negative predictive values were obtained with a cut-off concentration of 20.6 μM, and were 83%, 66%, 32% and 96%, respectively. Neutrophil number in BAL was a significant predictor of cyanide concentration (p<0.001). Cyanide concentration can distinguish between P. aeruginosa infected and uninfected BALs as a group, but not individually; therefore, cyanide is a poor diagnostic biomarker of P. aeruginosa infection. Cyanide levels in BAL are related to the level of neutrophilic inflammation. PMID:20562125

  4. Variation in Physician Practice Styles within and across Emergency Departments

    PubMed Central

    Van Parys, Jessica

    2016-01-01

    Despite the significant responsibility that physicians have in healthcare delivery, we know surprisingly little about why physician practice styles vary within or across institutions. Estimating variation in physician practice styles is complicated by the fact that patients are rarely randomly assigned to physicians. This paper uses the quasi-random assignment of patients to physicians in emergency departments (EDs) to show how physicians vary in their treatment of patients with minor injuries. The results reveal a considerable degree of variation in practice styles within EDs; physicians at the 75th percentile of the spending distribution spend 20% more than physicians at the 25th percentile. Observable physician characteristics do not explain much of the variation across physicians, but there is a significant degree of sorting between physicians and EDs over time, with high-cost physicians sorting into high-cost EDs as they gain experience. The results may shed light on why some EDs remain persistently higher-cost than others. PMID:27517464

  5. Urinary strontium and the risk of breast cancer: a case-control study in Guangzhou, China.

    PubMed

    Chen, Li-Juan; Tang, Lu-Ying; He, Jian-Rong; Su, Yi; Cen, Yu-Ling; Yu, Dan-Dan; Wu, Bang-Hua; Lin, Ying; Chen, Wei-Qing; Song, Er-Wei; Ren, Ze-Fang

    2012-01-01

    Strontium has been widely used in industries like electronic and pharmacy. It has a carcinogenic potential, however, and no study has been conducted to evaluate its effects on cancer risk. The aim of this study was to explore the possible association between strontium and breast cancer risk in a case-control study including 240 incident invasive breast cancer patients and 246 age-matched controls. We measured the urinary concentrations of strontium by inductively coupled plasma mass spectrometry, and conducted face-to-face interviews to obtain information on potential breast cancer risk factors. Multivariable analysis was used to estimate the association. Creatinine-adjusted levels [median (25th, 75th) μg/g] of strontium were 155.59 (99.05, 230.70) in the breast cancer patients and 119.62 (81.97, 163.76) in the controls. Women in the highest tertile of strontium showed 124% increased risk of breast cancer, when compared with those in the lowest tertile after adjustment for the potential risk factors [OR (95% CI): 2.24 (1.42-3.81)]. This association was particularly strong for HER2 positive breast cancer [OR (95% CI): 10.92 (3.53-33.77)], and only occurred among premenopausal women. These results suggest a potential role of strontium in the development of breast cancer and urge further studies on the environmental contamination and the physiological and pathological mechanisms of strontium. PMID:22172139

  6. Maternal consumption of polyphenol-rich foods in late pregnancy and fetal ductus arteriosus flow dynamics

    PubMed Central

    Zielinsky, P; Piccoli, A L; Manica, J L; Nicoloso, L H; Menezes, H; Busato, A; Moraes, M R; Silva, J; Bender, L; Pizzato, P; Aita, L; Alievi, M; Vian, I; Almeida, L

    2010-01-01

    Objective: To test the hypothesis that maternal consumption of polyphenol-rich foods during third trimester interferes with fetal ductal dynamics by inhibition of prostaglandin synthesis. Study Design: In a prospective analysis, Doppler ductal velocities and right-to-left ventricular dimensions ratio of 102 fetuses exposed to polyphenol-rich foods (daily estimated maternal consumption >75th percentile, or 1089 mg) were compared with 41 unexposed fetuses (flavonoid ingestion <25th percentile, or 127 mg). Result: In the exposed fetuses, ductal velocities were higher (systolic: 0.96±0.23 m/s; diastolic: 0.17±0.05 m/s) and right-to-left ventricular ratio was higher (1.23±0.23) than in unexposed fetuses (systolic: 0.61±0.18 m/s, P<0.001; diastolic: 0.11±0.04 m/s, P=0.011; right-to-left ventricular ratio: 0.94±0.14, P<0.001). Conclusion: As maternal polyphenol-rich foods intake in late gestation may trigger alterations in fetal ductal dynamics, changes in perinatal dietary orientation are warranted. PMID:19641513

  7. Relationship between particulate matter and childhood asthma - basis of a future warning system for central Phoenix

    NASA Astrophysics Data System (ADS)

    Dimitrova, R.; Lurponglukana, N.; Fernando, H. J. S.; Runger, G. C.; Hyde, P.; Hedquist, B. C.; Anderson, J.; Bannister, W.; Johnson, W.

    2012-03-01

    Statistically significant correlations between increase of asthma attacks in children and elevated concentrations of particulate matter of diameter 10 microns and less (PM10) were determined for metropolitan Phoenix, Arizona. Interpolated concentrations from a five-site network provided spatial distribution of PM10 that was mapped onto census tracts with population health records. The case-crossover statistical method was applied to determine the relationship between PM10 concentration and asthma attacks. For children ages 5-17, a significant relationship was discovered between the two, while children ages 0-4 exhibited virtually no relationship. The risk of adverse health effects was expressed as a function of the change from the 25th to 75th percentiles of mean level PM10 (36 μg m-3). This increase in concentration was associated with a 12.6% (95% CI: 5.8%, 19.4%) increase in the log odds of asthma attacks among children ages 5-17. Neither gender nor other demographic variables were significant. The results are being used to develop an asthma early warning system for the study area.

  8. Relationship between particulate matter and childhood asthma - basis of a future warning system for Central Phoenix

    NASA Astrophysics Data System (ADS)

    Dimitrova, R.; Lurponglukana, N.; Fernando, H. J. S.; Runger, G. C.; Hyde, P.; Hedquist, B. C.; Anderson, J.; Bannister, W.; Johnson, W.

    2011-10-01

    Statistically significant correlations between increase of asthma attacks in children and elevated concentrations of particulate matter of diameter 10 microns and less (PM10) were determined for metropolitan Phoenix, Arizona. Interpolated concentrations from a five-site network provided spatial distribution of PM10 that was mapped onto census tracts with population health records. The case-crossover statistical method was applied to determine the relationship between PM10 concentration and asthma attacks. For children ages 5-17, a significant relationship was discovered between the two, while children ages 0-4 exhibited virtually no relationship. The risk of adverse health effects was expressed as a function of the change from the 25th to 75th percentiles of mean level PM10 (36 μg m-3). This increase in concentration was associated with a 12.6% (95% CI: 5.8%, 19.4%) increase in the log odds of asthma attacks among children ages 5-17. Neither gender nor other demographic variables were significant. The results are being used to develop an asthma early warning system for the study area.

  9. Early Adolescent Exposure to Alcohol Advertising and Its Relationship to Underage Drinking

    PubMed Central

    Collins, Rebecca L.; Ellickson, Phyllis L.; McCaffrey, Daniel; Hambarsoomians, Katrin

    2009-01-01

    Purpose To determine whether early adolescents who are exposed to alcohol marketing are subsequently more likely to drink. Recent studies suggest that exposure to alcohol ads has a limited influence on drinking in mid-adolescence. Early adolescents may be more vulnerable to alcohol advertising effects. Methods Two in-school surveys of 1,786 South Dakota youth measured exposure to television beer advertisements, alcohol ads in magazines, in-store beer displays and beer concessions, radio-listening time, and ownership of beer promotional items during sixth grade, and drinking intentions and behavior at seventh grade. Multivariate regression equations predicted the two drinking outcomes using the advertising exposure variables and controlling for psychosocial factors and prior drinking. Results After adjusting for covariates, the joint effect of exposure to advertising from all six sources at Grade 6 was strongly predictive of Grade 7 drinking and Grade 7 intentions to drink. Youth in the 75th percentile of alcohol marketing exposure had a predicted probability of drinking that was 50% greater than that of youth in the 25th percentile. Conclusions Although causal effects are uncertain, policy makers should consider limiting a variety of marketing practices that could contribute to drinking in early adolescence. PMID:17531759

  10. Air pollution and daily hospital admissions in metropolitan Los Angeles.

    PubMed Central

    Linn, W S; Szlachcic, Y; Gong, H; Kinney, P L; Berhane, K T

    2000-01-01

    We used daily time-series analysis to evaluate associations between ambient carbon monoxide, nitrogen dioxide, particulate matter [less than and equal to] 10 microm in aerodynamic diameter (PM(10)), or ozone concentrations, and hospital admissions for cardiopulmonary illnesses in metropolitan Los Angeles during 1992-1995. We performed Poisson regressions for the entire patient population and for subgroups defined by season, region, or personal characteristics, allowing for effects of temporal variation, weather, and autocorrelation. CO showed the most consistently significant (p<0.05) relationships to cardiovascular admissions. A wintertime 25th-75th percentile increase in CO (1.1-2.2 ppm) predicted an increase of 4% in cardiovascular admissions. NO(2), and, to a lesser extent, PM(10) tracked CO and showed similar associations with cardiovascular disease, but O(3) was negatively or nonsignificantly associated. No significant demographic differences were found, although increased cardiovascular effects were suggested in diabetics, in whites and blacks (relative to Hispanics and Asians), and in persons older than 65 years of age. Pulmonary disease admissions associated more with NO(2) and PM(10) than with CO. Pulmonary effects were generally smaller than cardiovascular effects and were more sensitive to the choice of model. We conclude that in Los Angeles, atmospheric stagnation with high primary (CO/NO(2)/PM(10)) pollution, most common in autumn/winter, increases the risk of hospitalization for cardiopulmonary illness. Summer photochemical pollution (high O(3)) apparently presents less risk. Images Figure 1 Figure 2 PMID:10811569

  11. Job Exposure Matrix for Electric Shock Risks with Their Uncertainties

    PubMed Central

    Vergara, Ximena P.; Fischer, Heidi J.; Yost, Michael; Silva, Michael; Lombardi, David A.; Kheifets, Leeka

    2015-01-01

    We present an update to an electric shock job exposure matrix (JEM) that assigned ordinal electric shocks exposure for 501 occupational titles based on electric shocks and electrocutions from two available data sources and expert judgment. Using formal expert elicitation and starting with data on electric injury, we arrive at a consensus-based JEM. In our new JEM, we quantify exposures by adding three new dimensions: (1) the elicited median proportion; (2) the elicited 25th percentile; and (3) and the elicited 75th percentile of those experiencing occupational electric shocks in a working lifetime. We construct the relative interquartile range (rIQR) based on uncertainty interval and the median. Finally, we describe overall results, highlight examples demonstrating the impact of cut point selection on exposure assignment, and evaluate potential impacts of such selection on epidemiologic studies of the electric work environment. In conclusion, novel methods allowed for consistent exposure estimates that move from qualitative to quantitative measures in this population-based JEM. Overlapping ranges of median exposure in various categories reflect our limited knowledge about this exposure. PMID:25856552

  12. Association of joint occurrence of warm and dry conditions over Greece with anticyclonic activity during summer

    NASA Astrophysics Data System (ADS)

    Hatzaki, Maria; Nastos, Panagiotis; Polychroni, Iliana; Flocas, Helena A.; Kouroutzoglou, John; Dalezios, Nicolas R.

    2016-04-01

    Anticyclones are often associated with extreme phenomena, like prolonged droughts or heatwaves and, thus, they can significantly impact fauna and flora, water resources and public health. In this study, the association of the summer anticyclonic activity with the joint occurrence of extreme warm and dry conditions over Greece is explored. The warm and dry extreme conditions are defined by utilizing the Warm/Dry (WD) index for representative meteorological stations from sub-regions of Greece with different climatic features. The WD index is the number of days over a period (here summer) having at the same time mean air temperature > 75th percentile of daily mean temperature and precipitation < 25th percentile of daily precipitation amounts. The anticyclonic activity is determined by the density of the anticyclonic systems over the greater Mediterranean region, which, during summer, is maximized over the Balkans and the northern African coast. The anticyclonic system density has resulted from the comprehensive climatology of Mediterranean anticyclones that was assembled with the aid of the finding and tracking scheme of the University of Melbourne (MS scheme), using the ERA-Interim mean sea-level pressure fields for 1979-2012. The examination of inter-annual and spatial variations of the WD index in association with shifts of the anticyclonic maxima shows that the different sub-regions of Greece are not affected evenly, stressing the role of the complex topography of the region and the variations in the subtropical jet position.

  13. Congruence between patients’ preferred and perceived participation in medical decision-making: a review of the literature

    PubMed Central

    2014-01-01

    Background Patients are increasingly expected and asked to be involved in health care decisions. In this decision-making process, preferences for participation are important. In this systematic review we aim to provide an overview the literature related to the congruence between patients’ preferences and their perceived participation in medical decision-making. We also explore the direction of mismatched and outline factors associated with congruence. Methods A systematic review was performed on patient participation in medical decision-making. Medline, PsycINFO, CINAHL, EMBASE and the Cochrane Library databases up to September 2012, were searched and all studies were rigorously critically appraised. In total 44 papers were included, they sampled contained 52 different patient samples. Results Mean of congruence between preference for and perceived participation in decision-making was 60% (49 and 70 representing 25th and 75th percentiles). If no congruence was found, of 36 patient samples most patients preferred more involvement and of 9 patient samples most patients preferred less involvement. Factors associated with preferences the most investigated were age and educational level. Younger patients preferred more often an active or shared role as did higher educated patients. Conclusion This review suggests that a similar approach to all patients is not likely to meet patients’ wishes, since preferences for participation vary among patients. Health care professionals should be sensitive to patients individual preferences and communicate about patients’ participation wishes on a regular basis during their illness trajectory. PMID:24708833

  14. Curing Hepatitis C in Liver Transplant Recipients Is Associated with Changes in Immunosuppressant Use

    PubMed Central

    Saab, Sammy; Rheem, Justin; Jimenez, Melissa; Bau, Sherona; Choi, Gina; Durazo, Francisco; El Kabany, Mohammed; Han, Steven; Farid, Alexander; Jamal, Naadir; Grotts, Jonathan; Elashoff, David; Busuttil, Ronald W.

    2016-01-01

    Background and Aims: All-oral interferon-free antivirals are highly effective in treating recurrent hepatitis C (HCV) infection in liver transplant (LT) recipients. The aim of the study was to assess immunosuppression needs after achieving a sustained viral response (SVR). Methods: We compared immunosuppression needs before and after achieving a SVR in adult LT recipients treated for recurrent HCV infection with all-oral direct acting agents. Results: We identified 52 liver LT treated recipients who achieved a SVR. The median (25th and 75th percentile interquartile range [IQR]) age was 62 years (57.75, 65). Most recipients received tacrolimus (TAC) for their immunosuppressant regimen. After achieving SVR, there was no statistically significant difference in daily dose of TAC unadjusted per weight (p > 0.05). However, there was a statistically significant decrease in daily dose of TAC adjusted per weight, serum levels of TAC, and the product of glomerular filtration rate and TAC. No statistically significant differences in cyclosporine unadjusted/adjusted per weight daily dose or serum levels were noted. Conclusions: Immunosuppression needs were increased for those patients treated with TAC but not cyclosporine. LT recipients prescribed TAC require close monitoring after treatment completion to avoid potential risk of acute rejection. PMID:27047770

  15. Acute and sub-acute effects of repetitive kicking on hip adduction torque in injury-free elite youth soccer players.

    PubMed

    Jensen, Jesper; Bandholm, Thomas; Hölmich, Per; Thorborg, Kristian

    2014-01-01

    Hip adduction strength is important for kicking and acceleration in soccer players. Changes in hip adduction strength may therefore have an effect on soccer players' athletic performance. The purpose of this study was to investigate the acute and sub-acute effects of a kicking drill session on hip strength, concerning isometric hip adduction, abduction and flexion torque of the kicking leg and the supporting leg. Ten injury-free male elite soccer players, mean ± s age of 15.8 ± 0.4 years participated. All players underwent a specific 20 min kicking drill session, comprising 45 kicks. The players were tested the day before, 15 min after and 24 h after the kicking drill session by a blinded tester using a reliable test procedure. The isometric hip-action and leg-order were randomized. For the kicking leg, hip adduction torque increased from 2.45 (2.19-2.65) Nm ∙ kg(-1), median (25th-75th percentiles), at pre-kicking to 2.65 (2.55-2.81) Nm ∙ kg(-1) (P = 0.024) 24 h post-kicking. This may have implications for the soccer player's ability to maximally activate the hip adductors during kicking and acceleration, and thereby improve performance the day after a kicking drill session. PMID:24669834

  16. Emotion Suppression and Mortality Risk Over a 12-Year Follow-up

    PubMed Central

    Chapman, Benjamin P.; Fiscella, Kevin; Kawachi, Ichiro; Duberstein, Paul; Muennig, Peter

    2013-01-01

    Objective Suppression of emotion has long been suspected to have a role in health, but empirical work has yielded mixed findings. We examined the association between emotion suppression and all-cause, cardiovascular, and cancer mortality over 12 years of follow-up in a nationally representative US sample. Methods We used the 2008 General Social Survey-National Death Index (NDI) cohort, which included an emotion suppression scale administered to 729 people in 1996. Prospective mortality follow up between 1996 and 2008 of 111 deaths (37 by cardiovascular disease, 34 by cancer) was evaluated using Cox proportional hazards models adjusted for age, gender, education, and minority race/ethnicity. Results The 75th vs. 25th percentile on the emotional suppression score was associated with hazard ratio (HR) of 1.35 (95% Confidence Interval [95% CI] = 1.00, 1.82; p = .049) for all-cause mortality. For cancer and cardiovascular disease mortality, the HRs were 1.70 (95% CI = 1.01, 2.88, p = 0.049) and 1.47 (95% CI = .87, 2.47, p = 0.148) respectively. Conclusions Emotion suppression may convey risk for earlier death, including death from cancer. Further work is needed to better understand the biopsychosocial mechanisms for this risk, as well as the nature of associations between suppression and different forms of mortality. PMID:24119947

  17. Variation in surgical trauma and baseline pain intensity: effects on assay sensitivity of an analgesic trial.

    PubMed

    Breivik, E K; Björnsson, G A

    1998-08-01

    The aims of this study were to test the hypotheses that the type of 3rd molar removal determines baseline pain and that baseline pain influences analgesic assay sensitivity. Three groups of patients were studied: (i) 100 patients that had one fully erupted maxillary 3rd molar extracted; (ii) 95 patients that had one lower impacted 3rd molar surgically removed; and (iii) 98 patients that had two ipsilateral impacted 3rd molars surgically removed. In a randomized, double-blind fashion, the patients received (every third hour, three times) either: (i) paracetamol 1g; (ii) paracetamol 1g plus codeine 60 mg; or (iii) placebo. Baseline pain intensity (100 mm Visual Analogue Scale) was significantly lower after extraction (8 mm (2-20)) (=median (25th -75th percentile) than after surgical removal of one 3rd molar (35 mm (15-57)), which was significantly lower than pain intensity after surgical removal of two 3rd molars (49 mm (24-82)). Analgesic effects of the active test drugs were superior to placebo. Paracetamol with and without codeine could be distinguished in patients after surgical removal of one 3rd molar. In conclusion, baseline pain was related to the degree of surgical trauma, but large inter-individual variation in baseline pain intensity reduced the ability to distinguish between paracetamol with and without codeine. PMID:9708687

  18. Fat Mass Is Inversely Associated with Serum Carboxymethyl-Lysine, An Advanced Glycation End Product, in Adults12

    PubMed Central

    Semba, Richard D.; Arab, Lenore; Sun, Kai; Nicklett, Emily J.; Ferrucci, Luigi

    2011-01-01

    High levels of circulating advanced glycation end products (AGE) are associated with cardiovascular disease, diabetes, chronic kidney disease, and increased mortality, but factors that influence levels of circulating AGE are not well known. Our objective was to characterize the relationship between serum carboxymethyl-lysine (CML), a major circulating AGE, and body composition in adults. In a cross-sectional study, total body DXA was performed and serum CML was measured in 592 adults, aged 26–93 y, from the Baltimore Longitudinal Study of Aging. Median (25th, 75th percentile) CML concentrations were 2.26 (1.86, 2.67) μmol/L. Total fat mass [β = −0.17 (95% CI −0.10, −0.24); P < 0.0001], truncal fat mass [β = −0.17 (95% CI −0.10, −0.25); P < 0.0001], and appendicular fat mass [β = −0.13 (95% CI −0.05, −0.20); P = 0.001] per 1 SD increase were inversely associated with serum CML in separate multivariate linear regression models, adjusting for age, sex, BMI, systolic blood pressure, TG, HDL cholesterol, and renal function. Lean body mass was not independently associated with serum CML. These findings suggest that serum CML concentration is strongly affected by body fat, possibly because CML is preferentially deposited in fat tissue or because adipocytes affect the metabolism of AGE. PMID:21775524

  19. Tolerability of sirolimus: a decade of experience at a single cardiac transplant center.

    PubMed

    Thibodeau, Jennifer T; Mishkin, Joseph D; Patel, Parag C; Kaiser, Patricia A; Ayers, Colby R; Mammen, Pradeep P A; Markham, David W; Ring, William Steves; Peltz, Matthias; Drazner, Mark H

    2013-01-01

    Sirolimus is used in cardiac transplant recipients to prevent rejection, progression of cardiac allograft vasculopathy, and renal dysfunction. However, sirolimus has many potential side effects and its tolerability when used outside of clinical trials is not well established. We describe a decade of experience with sirolimus in cardiac transplant recipients at our institution. We retrospectively reviewed records of all adult cardiac transplant recipients living between September 1999 and February 2010 (n = 329) and identified 67 patients (20%) who received sirolimus. The indications for sirolimus were cardiac allograft vasculopathy (67%), renal dysfunction (25%), rejection (4%), and intolerability of tacrolimus (3%). One-third of patients discontinued sirolimus at a median (25th, 75th percentiles) of 0.9 (0.2, 1.6) yr of duration. Over 70% of subjects experienced an adverse event attributed to sirolimus. Adverse events were associated with higher average sirolimus levels (9.1 ng/mL vs. 7.1 ng/mL, p = 0.004). We conclude that sirolimus is frequently used in cardiac transplant recipients (20%) and commonly causes side effects, often necessitating discontinuation. Higher average sirolimus levels were associated with adverse events, suggesting that tolerability may improve if levels are maintained within the lower end of the current therapeutic range; however, the improvement in tolerability would need to be balanced with the potential for decreased efficacy. PMID:24304376

  20. Nationwide variation in the effects of temperature on infectious gastroenteritis incidence in Japan

    NASA Astrophysics Data System (ADS)

    Onozuka, Daisuke; Hagihara, Akihito

    2015-08-01

    Although several studies have investigated the effects of temperature on the incidence of infectious gastrointestinal disease in a single city or region, few have investigated variations in this association using nationwide data. We obtained weekly data, gathered between 2000 and 2012, pertaining to infectious gastroenteritis cases and weather variability in all 47 Japanese prefectures. A two-stage analysis was used to assess the nonlinear and delayed relationship between temperature and morbidity. In the first stage, a Poisson regression allowing for overdispersion in a distributed lag nonlinear model was used to estimate the prefecture-specific effects of temperature on morbidity. In the second stage, a multivariate meta-analysis was applied to pool estimates at the national level. The pooled overall relative risk (RR) was highest in the 59.9th percentile of temperature (RR, 1.08; 95% CI: 1.01, 1.15). Meta-analysis results also indicated that the estimated pooled RR at lower temperatures (25th percentile) began immediately but did not persist, whereas an identical estimate at a higher temperature (75th percentile) was delayed but persisted for several weeks. Our results suggest that public health strategies aimed at controlling temperature-related infectious gastroenteritis may be more effective when tailored according to region-specific weather conditions.

  1. Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects.

    PubMed

    Radikova, Z; Koska, J; Huckova, M; Ksinantova, L; Imrich, R; Vigas, M; Trnovec, T; Langer, P; Sebokova, E; Klimes, I

    2006-05-01

    Demanding measurement of insulin sensitivity using clamp methods does not simplify the identification of insulin resistant subjects in the general population. Other approaches such as fasting- or oral glucose tolerance test-derived insulin sensitivity indices were proposed and validated with the euglycemic clamp. Nevertheless, a lack of reference values for these indices prevents their wider use in epidemiological studies and clinical practice. The aim of our study was therefore to define the cut-off points of insulin resistance indices as well as the ranges of the most frequently obtained values for selected indices. A standard 75 g oral glucose tolerance test was carried out in 1156 subjects from a Caucasian rural population with no previous evidence of diabetes or other dysglycemias. Insulin resistance/sensitivity indices (HOMA-IR, HOMA-IR2, ISI Cederholm, and ISI Matsuda) were calculated. The 75th percentile value as the cut-off point to define IR corresponded with a HOMA-IR of 2.29, a HOMA-IR2 of 1.21, a 25th percentile for ISI Cederholm, and ISI Matsuda of 57 and 5.0, respectively. For the first time, the cut-off points for selected indices and their most frequently obtained values were established for groups of subjects as defined by glucose homeostasis and BMI. Thus, insulin-resistant subjects can be identified using this simple approach. PMID:16804799

  2. Methemoglobinemia in critically ill patients during extended hemodialysis and simultaneous disinfection of the hospital water supply

    PubMed Central

    2009-01-01

    Introduction To evaluate the cause of methemoglobinemia in patients undergoing extended daily hemodialysis/hemodiafiltration we analyzed the relationship between methemoglobinemia and the water disinfection schedule of the hospital. Methods We reviewed all arterial blood gas analyses, obtained over a one-year period, in patients undergoing extended hemodialysis/hemodiafiltration, and compared the methemoglobin concentrations obtained on the days when the water supply was disinfected, using a hydrogen peroxide/silver ion preparation, with data measured on disinfection-free days. Results The evaluation of 706 measurements revealed a maximum methemoglobin fraction of 1.0 (0.8; 1.2) % (median and 25th; 75th percentiles) during hemodialysis/hemodiafiltration on the disinfection-free days. The methemoglobin fraction increased to 5.9 (1.3; 8.4) % with a maximal value of 12.2% on the days of water disinfection (P < 0.001 compared to disinfection-free days). Spot checks on hydrogen peroxide concentrations in the water supply, the permeate, and the dialysate, using a semi-quantitative test, demonstrated levels between 10 and 25 mg/l during water disinfection. Conclusions Our results demonstrate that even a regular hospital water disinfection technique can be associated with significant methemoglobinemia during extended hemodialysis. Clinicians should be aware of this potential hazard. PMID:19821985

  3. An aggregate analysis of personal care products in the environment: Identifying the distribution of environmentally-relevant concentrations.

    PubMed

    Hopkins, Zachary R; Blaney, Lee

    2016-01-01

    Over the past 3-4 decades, per capita consumption of personal care products (PCPs) has steadily risen, resulting in increased discharge of the active and inactive ingredients present in these products into wastewater collection systems. PCPs comprise a long list of compounds employed in toothpaste, sunscreen, lotions, soaps, body washes, and insect repellants, among others. While comprehensive toxicological studies are not yet available, an increasing body of literature has shown that PCPs of all classes can impact aquatic wildlife, bacteria, and/or mammalian cells at low concentrations. Ongoing research efforts have identified PCPs in a variety of environmental compartments, including raw wastewater, wastewater effluent, surface water, wastewater solids, sediment, groundwater, and drinking water. Here, an aggregate analysis of over 5000 reported detections was conducted to better understand the distribution of environmentally-relevant PCP concentrations in, and between, these compartments. The distributions were used to identify whether aggregated environmentally-relevant concentration ranges intersected with available toxicity data. For raw wastewater, wastewater effluent, and surface water, a clear overlap was present between the 25th-75th percentiles and identified toxicity levels. This analysis suggests that improved wastewater treatment of antimicrobials, UV filters, and polycyclic musks is required to prevent negative impacts on aquatic species. PMID:27128715

  4. Matthew effects in reading comprehension: myth or reality?

    PubMed

    Protopapas, Athanassios; Sideridis, Georgios D; Mouzaki, Angeliki; Simos, Panagiotis G

    2011-01-01

    The presence of Matthew effects was tested in students of varying reading, spelling, and vocabulary skills. A cross-sequential design was implemented, following 587 Grade 2 through 4 students across five measurement points (waves) over 2 years. Students were administered standardized assessments of reading, spelling, and vocabulary. Results indicated that the hypothesized fan-spread pattern for Matthew effects was not evident. Low and high ability groups were formed based on 25th and 75th percentile cutoffs on initial measures of spelling, reading accuracy and fluency, vocabulary, and reading comprehension. Multilevel modeling suggested that low and high ability groups had significantly different starting points (intercepts) and their pattern of growth on passage comprehension did not indicate that the gap would increase over time. Instead, some analyses, especially of the youngest cohorts, showed significant convergence. However, there was no evidence of eventually closing the gap. Thus, although the poor students may not be getting poorer, they do not get sufficiently richer either. PMID:21856992

  5. The burden of ambient temperature on years of life lost in Guangzhou, China

    NASA Astrophysics Data System (ADS)

    Yang, Jun; Ou, Chun-Quan; Guo, Yuming; Li, Li; Guo, Cui; Chen, Ping-Yan; Lin, Hua-Liang; Liu, Qi-Yong

    2015-08-01

    Limited evidence is available on the association between temperature and years of life lost (YLL). We applied distributed lag non-linear model to assess the nonlinear and delayed effects of temperature on YLL due to cause-/age-/education-specific mortality in Guangzhou, China. We found that hot effects appeared immediately, while cold effects were more delayed and lasted for 14 days. On average, 1 °C decrease from 25th to 1st percentile of temperature was associated with an increase of 31.15 (95%CI: 20.57, 41.74), 12.86 (8.05, 17.68) and 6.64 (3.68, 9.61) YLL along lag 0-14 days for non-accidental, cardiovascular and respiratory diseases, respectively. The corresponding estimate of cumulative hot effects (1 °C increase from 75th to 99th percentile of temperature) was 12.71 (-2.80, 28.23), 4.81 (-2.25, 11.88) and 2.81 (-1.54, 7.16). Effect estimates of cold and hot temperatures-related YLL were higher in people aged up to 75 years and persons with low education level than the elderly and those with high education level, respectively. The mortality risks associated with cold and hot temperatures were greater on the elderly and persons with low education level. This study highlights that YLL provides a complementary method for assessing the death burden of temperature.

  6. A Randomized Clinical Trial Evaluating Therapeutic Drug Monitoring (TDM) for Protease Inhibitor–Based Regimens in Antiretroviral-Experienced HIV-Infected Individuals: Week 48 Results of the A5146 Study

    PubMed Central

    Albrecht, Mary; Mukherjee, A. Lisa; Tierney, Camlin; Morse, Gene D.; Dykes, Carrie; Klingman, Karin L.; Demeter, Lisa M.

    2012-01-01

    Background We devised an open-label, randomized trial to evaluate whether therapeutic drug monitoring (TDM) of protease inhibitors (PIs) and dose escalation based upon a normalized inhibitory quotient (NIQ), which integrates PI trough concentration and drug resistance, could improve virologic outcome in PI-experienced patients with treatment failure. Secondary analyses through 48 weeks are presented. Methods Eligible HIV-infected subjects with a screening viral load of ≥1000 copies/mL initiated a new PI-based regimen at entry and had NIQ performed at week 2. Subjects with an NIQ ≤1 were randomized at week 4 to a standard-of-care (SOC) arm or TDM arm featuring PI dose escalation. Results One hundred and eighty-three subjects were randomized. There was no significant treatment difference in change from randomization to week 48 in HIV-1 RNA [P = .13, median (25th, 75th percentile log10 copies/mL change): −0.03 (−0.74, 0.62) with TDM and 0.11 (−2.3, 0.82) with SOC]. In subgroup analysis, patients with ≥0.69 active PIs benefited from TDM compared to those with <0.69 active PIs (P = .05). Conclusions While the TDM strategy of PI dose escalation did not improve virologic response at week 48 overall, in subgroup analysis, TDM favorably impacted virologic outcome in subjects taking PI-based regimens with moderate antiviral activity. PMID:22044856

  7. Haemoglobin recovery among HIV-1 infected patients on zidovudine-based antiretroviral therapy and other regimens in north-central Nigeria.

    PubMed

    Parrish, Deidra D; Blevins, Meridith; Megazzini, Karen M; Shepherd, Bryan E; Mohammed, Mukhtar Y; Wester, C William; Vermund, Sten H; Aliyu, Muktar H

    2014-04-01

    We conducted a study to assess trends in haemoglobin recovery among HIV-infected patients initiated on zidovudine-based combination antiretroviral therapy (cART) stratified by baseline haemoglobin level. Haemoglobin data from non-pregnant adult patients initiating cART in rural north-central Nigeria between June 2009 and May 2011 were analysed using a linear mixed effects model to assess the interaction between time, zidovudine-containing regimen and baseline haemoglobin level on the outcome of subsequent haemoglobin level. Best-fit curves were created for baseline haemoglobin in the 10th, 25th, 75th and 90th percentiles. We included 313 patients with 736 measures of haemoglobin in the analysis (239 on zidovudine and 74 on non-zidovudine-containing regimens). Median haemoglobin increased over time in both groups, with differences in haemoglobin response over time related to baseline haemoglobin levels and zidovudine use (p = 0.003). The groups of patients on zidovudine at the 10th and 90th percentiles had downward sloping curves while all other groups had upward trending haemoglobin levels. Although haemoglobin levels increased overall for patients on zidovudine-containing regimens, for those in the 10th and 90th percentiles haemoglobin levels trended downward over time. These results have implications for decisions regarding when to initiate, switch from or avoid the use of zidovudine. PMID:24104694

  8. Gene expression profiling in the Cynomolgus macaque Macaca fascicularis shows variation within the normal birth range

    PubMed Central

    2011-01-01

    Background Although an adverse early-life environment has been linked to an increased risk of developing the metabolic syndrome, the molecular mechanisms underlying altered disease susceptibility as well as their relevance to humans are largely unknown. Importantly, emerging evidence suggests that these effects operate within the normal range of birth weights and involve mechanisms of developmental palsticity rather than pathology. Method To explore this further, we utilised a non-human primate model Macaca fascicularis (Cynomolgus macaque) which shares with humans the same progressive history of the metabolic syndrome. Using microarray we compared tissues from neonates in the average birth weight (50-75th centile) to those of lower birth weight (5-25th centile) and studied the effect of different growth trajectories within the normal range on gene expression levels in the umbilical cord, neonatal liver and skeletal muscle. Results We identified 1973 genes which were differentially expressed in the three tissue types between average and low birth weight animals (P < 0.05). Gene ontology analysis identified that these genes were involved in metabolic processes including cellular lipid metabolism, cellular biosynthesis, cellular macromolecule synthesis, cellular nitrogen metabolism, cellular carbohydrate metabolism, cellular catabolism, nucleotide and nucleic acid metabolism, regulation of molecular functions, biological adhesion and development. Conclusion These differences in gene expression levels between animals in the upper and lower percentiles of the normal birth weight range may point towards early life metabolic adaptations that in later life result in differences in disease risk. PMID:21999700

  9. Estimation of dietary exposure to acrylamide of Polish teenagers from an urban environment.

    PubMed

    Wyka, Joanna; Tajner-Czopek, Agnieszka; Broniecka, Anna; Piotrowska, Ewa; Bronkowska, Monika; Biernat, Jadwiga

    2015-01-01

    The aim of this study was to evaluate the dietary exposure to acrylamide (AA) in a group of teenagers (n = 261) from an urban environment. The intake of AA from food was estimated based on a 7-day food record diary (consecutive days). The food rations obtained (n = 1827) were used to calculate the amounts of the consumed food products, which were the main sources of AA. In the case of girls, the estimated dietary intake of AA per kg body weight (BW) amounted to 0.09 µg/kg BW/day (50th percentile), 0.32 µg/kg BW/day (75th percentile) and 1.04 µg/kg BW/day (95th percentile), and among boys it was 0.13, 0.41, and 1.18 µg/kg BW/day, respectively. The main sources of AA exposure were French fries, potato crisps, corn flakes, bread and salty sticks. The lowest values for margin of exposure (MOE) were calculated for the P95th percentiles of exposure, and ranged from 152 to 173. PMID:25445510

  10. Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women.

    PubMed

    Teeguarden, Justin G; Twaddle, Nathan C; Churchwell, Mona I; Doerge, Daniel R

    2016-06-01

    Despite its very low oral bioavailability and rapid elimination, multiple reports of unexpectedly high bisphenol A (BPA) concentrations in the serum of pregnant mothers or cord blood have raised questions about BPA exposures during pregnancy. Thirty healthy pregnant women recruited to the study were evaluated for total BPA exposure over a 30-h period comprising one-half day in the field and one day in a clinical setting. BPA and its metabolites were measured in serum and total BPA was measured in matching urine samples. The mean total exposure was similar to the 50(th) percentile of exposure for U.S. women and pregnant women in a large North American cohort. Twenty volunteers had total daily exposures equal to or exceeding the U.S. mean, and six volunteers had exposures exceeding the 75th percentile. Women working as cashiers did not have higher total BPA exposure. BPA was detected in some serum samples (0.25-0.51 ng/ml), but showed no relationship to total BPA in corresponding urine samples, no relationship to total BPA exposure, and had unconjugated BPA fractions of 60-80%, consistent with established criteria for sample contamination. We conclude that typical exposures of North American pregnant women produce internal exposures to BPA in the picomolar range. PMID:27038865

  11. Do the pre-service education programmes for midwives in India prepare confident ‘registered midwives’? A survey from India

    PubMed Central

    Sharma, Bharati; Hildingsson, Ingegerd; Johansson, Eva; Prakasamma, Malvarappu; Ramani, K.V.; Christensson, Kyllike

    2015-01-01

    Objective The graduates of the diploma and degree programmes of nursing and midwifery in India are considered skilled birth attendants (SBAs). This paper aimed to assess the confidence of final-year students from pre-service education programmes (diploma and bachelor's) in selected midwifery skills from the list of midwifery competencies of the International Confederation of Midwives (ICM). Design A cross-sectional survey was conducted in Gujarat, India, involving 633 final-year students from 25 educational institutions (private or government), randomly selected, stratified by the type of programme (diploma and bachelor's). Students assessed their confidence on a four-point scale, in four midwifery competency domains – antepartum, intrapartum, postpartum, and newborn care. Explorative factor analysis was used to reduce skill statements into separate subscales for each domain. Results Overall, 25–40% of students scored above the 75th percentile and 38–50% below the 50th percentile of confidence in all subscales for antepartum, intrapartum, postpartum, and newborn care. The majority had not attended the required number of births prescribed by the Indian Nursing Council. Conclusions The pre-service education offered in the diploma and bachelor's programmes in Gujarat does not prepare confident SBAs, as measured on selected midwifery competencies of the ICM. One of the underlying reasons was less clinical experience during their education. The duration, content, and pedagogy of midwifery education within the integrated programmes need to be reviewed. PMID:26649550

  12. Silver Anniversary Conference: 25 Years of Higher Education Collective Bargaining. Proceedings of the Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education and the Professions. School of Public Affairs, Baruch College, City University of New York (25th, New York, NY, April 1997).

    ERIC Educational Resources Information Center

    Johnson, Beth H., Ed.

    The 21 papers in this proceedings document are grouped into six sections which discuss the future of the U.S. labor movement; the future of tenure; faculty, unions, and management; technology and collective bargaining; fiscal problems in higher education; and legal issues in higher education. The papers are: (1) "Labor Relations for the 21st…

  13. Minerals, lands, and geology for the common defence and general welfare, Volume 3, 1904-1939 : A history of geology in relation to the development of public-land, federal-science, and mapping policies and the development of mineral resources in the United States from the 25th to the 60th year of the U.S. Geological Survey

    USGS Publications Warehouse

    Rabbitt, Mary C.

    1986-01-01

    Mrs. Rabbitt's third volume covers the years 1904 to 1939, from the beginning of the conservation movement under Theodore Roosevelt to the beginning of World War II. From a national perspective, these were years of great development and change in the use of energy, trouble in the coal industry, and a great expansion in the oil industry. They were also years in which the public perceived for the first time that the Nation's mineral resources are not infinite, and the mineral industry realized its dependence on international trade. In these years, water became an increasingly valuable commodity, and the need for a national mapping program became abundantly evident. These were also the years when the Federal Government for the most part practiced stringent economy in funding science, but State and municipal agencies increasingly sought the services of the Survey's topographic and water specialists to aid in the solution of local problems. The balance maintained between fundamental and practical research during the first 25 years was more than once upset during the next 25 years, but the successful struggle to maintain a significant level of research laid the groundwork for the tremendous expansion in the Survey in the subsequent years.

  14. Recognizing excellence in maternal and child health (MCH) epidemiology: the 2012 Co-hosted 18th MCH Epidemiology Conference and 22nd CityMatCH Urban MCH Leadership Conference, the 25th anniversary of the MCH Epidemiology Program, and the National MCH Epidemiology Awards.

    PubMed

    Kroelinger, Charlan D; Jones, Jessica; Barfield, Wanda D; Kogan, Michael D

    2014-09-01

    In December 2012, multiple leading agencies in the field of Maternal and Child Health (MCH) partnered to co-host a national MCH Epidemiology Conference. The Conference offered opportunities for peer exchange; presentation of new scientific methodologies, programs, and policies; dialogue on changes in the MCH field; and discussion of emerging MCH issues relevant to the work of MCH professionals. During the Conference, the MCH Epidemiology Program celebrated 25 years of success and partnership, and 16 MCH agencies presented six deserving health researchers and leaders with national awards in the areas of advancing knowledge, effective practice, outstanding leadership, excellence in teaching and mentoring, and young professional achievement. In September 2014, building on knowledge gained and changes in the field of MCH, leading agencies including the Centers for Disease Control and Prevention, the Health Resources and Services Administration, CityMatCH, and the Association of MCH Programs plan to replicate the achievements of 2012 through the implementation of a fully integrated national conference: the CityMatCH Leadership and MCH Epidemiology Conference. PMID:25091642

  15. In Vitro Pharmacodynamics of Vancomycin against Methicillin-Susceptible and -Resistant Staphylococcus aureus: Considering the Variability in Observed Tissue Exposure

    PubMed Central

    Hamada, Yukihiro; Kuti, Joseph L.

    2015-01-01

    Vancomycin is considered a first-line antibiotic for complicated skin and skin structure infections (cSSSI) because of the risk of methicillin-resistant Staphylococcus aureus (MRSA). The vancomycin exposure of tissue can vary widely in patients with cSSSI, yet most models test only the average exposure. The in vitro pharmacodynamic model was used to simulate three tissue exposure levels attained by administering vancomycin at 1 g every 12 h (q12h), based on the median (50th), 25th, and 10th percentile tissue area under the concentration-time curve (AUC) values observed during an in vivo microdialysis study of diabetic patients. Four clinical isolates (two of MRSA [vancomycin MIC, 1 and 2 μg/ml] and two of methicillin-susceptible S. aureus [MSSA] [MIC, 1 and 2 μg/ml]) were evaluated. Experiments were performed over 72 h in duplicate. Time-kill curves were constructed, and the area under the bacterial killing and regrowth curve (AUBC) during the final 24-h dosing interval (48 to 72 h) (AUBC48–72) was calculated. Reductions in the 72-h number of CFU/ml and AUBC48–72 at the different exposure levels were compared. Target tissue vancomycin exposure levels for the 50th (AUC0–12, 102.0 ± 9.1 μg · h/ml), 25th (AUC0–12, 44.3 ± 1.8 μg · h/ml), and 10th (AUC0–12, 25.3 ± 3.1 μg · h/ml) percentiles were obtained in all studies. No differences in the 72-h number of CFU or AUBC were observed between exposure levels when all of the isolates were analyzed together. However, for the two MRSA isolates, the 10th percentile exposure level achieved a lower 72-h number of CFU/ml (−1.4 ± 0.4 log10 CFU/ml, P = 0.007) and a greater AUBC48–72 (97.1 ± 20.0 log10 CFU · h/ml, P = 0.011) than the higher exposure levels. The majority of the tissue exposure levels achieved with a vancomycin dosing regimen of 1 g q12h resulted in substantial killing of MSSA and MRSA; however, the lowest exposure levels observed in a minority of the population may explain the poor

  16. In Vitro Pharmacodynamics of Vancomycin against Methicillin-Susceptible and -Resistant Staphylococcus aureus: Considering the Variability in Observed Tissue Exposure.

    PubMed

    Hamada, Yukihiro; Kuti, Joseph L; Nicolau, David P

    2016-02-01

    Vancomycin is considered a first-line antibiotic for complicated skin and skin structure infections (cSSSI) because of the risk of methicillin-resistant Staphylococcus aureus (MRSA). The vancomycin exposure of tissue can vary widely in patients with cSSSI, yet most models test only the average exposure. The in vitro pharmacodynamic model was used to simulate three tissue exposure levels attained by administering vancomycin at 1 g every 12 h (q12h), based on the median (50th), 25th, and 10th percentile tissue area under the concentration-time curve (AUC) values observed during an in vivo microdialysis study of diabetic patients. Four clinical isolates (two of MRSA [vancomycin MIC, 1 and 2 μg/ml] and two of methicillin-susceptible S. aureus [MSSA] [MIC, 1 and 2 μg/ml]) were evaluated. Experiments were performed over 72 h in duplicate. Time-kill curves were constructed, and the area under the bacterial killing and regrowth curve (AUBC) during the final 24-h dosing interval (48 to 72 h) (AUBC48-72) was calculated. Reductions in the 72-h number of CFU/ml and AUBC48-72 at the different exposure levels were compared. Target tissue vancomycin exposure levels for the 50th (AUC0-12, 102.0 ± 9.1 μg · h/ml), 25th (AUC0-12, 44.3 ± 1.8 μg · h/ml), and 10th (AUC0-12, 25.3 ± 3.1 μg · h/ml) percentiles were obtained in all studies. No differences in the 72-h number of CFU or AUBC were observed between exposure levels when all of the isolates were analyzed together. However, for the two MRSA isolates, the 10th percentile exposure level achieved a lower 72-h number of CFU/ml (-1.4 ± 0.4 log10 CFU/ml, P = 0.007) and a greater AUBC48-72 (97.1 ± 20.0 log10 CFU · h/ml, P = 0.011) than the higher exposure levels. The majority of the tissue exposure levels achieved with a vancomycin dosing regimen of 1 g q12h resulted in substantial killing of MSSA and MRSA; however, the lowest exposure levels observed in a minority of the population may explain the poor vancomycin response

  17. A resolution recognizing the 75th Anniversary of the Welfare Program of The Church of Jesus Christ of Latter-day Saints and the significant impact of the Welfare Program in the United States and throughout the world in helping people in need.

    THOMAS, 112th Congress

    Sen. Hatch, Orrin G. [R-UT

    2011-11-15

    11/15/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S7584-7585; text as passed Senate: CR S7584-7585; text of measure as introduced: CR S7454-7455) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  18. S.Res.323 — 112th Congress (2011-2012) A resolution recognizing the 75th Anniversary of the Welfare Program of The Church of Jesus Christ of Latter-day Saints and the significant impact of the Welfare Program in the United States and...

    THOMAS, 112th Congress

    Sen. Hatch, Orrin G. [R-UT

    2011-11-15

    11/15/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S7584-7585; text as passed Senate: CR S7584-7585; text of measure as introduced: CR S7454-7455) (All Actions)

  19. Deletion 6(p25.1) in a child with mild dysmorphic features and absence of major eye malformations: Implications for the location of genes involved in ocular development

    SciTech Connect

    Tepperberg, J.H.; Rao, K.W.; Albright, S.G.

    1994-09-01

    The authors describe a young girl with an apparently terminal deletion of chromosome 6 at p25.1 Fluorescence in situ hybridization with a chromosome 6 painting probe (ONCOR), showed that the abnormal chromosome 6 is composed entirely of chromosome 6 material. Analysis of the parents chromosomes with the same paint probe ruled out an inherited structural abnormality. To our knowledge, this case is the smallest terminal deletion of 6p yet reported. The patient is a 4 year, 6 month old female who was 3300g at birth. She has global developmental delay and little intelligible speech. Her weight is at the 25th centile, height at the 50th centile for a 3 1/2-year-old, and head circumference at the 25th centile. The eyes are prominent with shallow orbits. She has mild hyperopia and astigmatism. The philtrum is short and the vermillion border is thin. The midface is hypoplastic and there is dental malocclusion. Some of the common features reported in individuals with larger 6p terminal deletions include mental retardation, microcephaly, eye and ear abnormalities, short neck/excess nuchal skin, and flat broad nasal bridge. Our patient lacks several of the features reported in patients with larger deletions of 6p, including the more severe eye defects (e.g., anterior segment malformations including Peters and Rieger anomalies) described in individuals with 6p23 or 24 terminal deletions. This patient could be important in mapping the critical region for 6p deletion syndrome and for localizing clinical findings to a specific area of 6p. This case also raises the possibility that the gene(s) on 6p important for ocular growth and development are located proximal to 6p25.1.

  20. The legacy of the IGY

    NASA Astrophysics Data System (ADS)

    Friedman, Herbert

    We are now at the point of celebrating three milestones of international cooperation in sun—earth research: the 100th anniversary of the First International Polar Year (1882-1883) the 50th anniversary of the Second Polar Year (1932-1933) and the 25th anniversary of the International Geophysical Year (1957-1958). Credit for the concept of the First Polar Year goes to an Austrian Lieutenant, Karl Weyprecht. He expressed the philosophy of scientific cooperation in the following bold language delivered in a statement to the Hall of the Austrian Academy of Sciences on January 18, 1875:Purely geographical research and Arctic topography, which until now have stood in the foreground of all polar expeditions, must, with respect to the great scientific questions, recede into the background. The answers, though, will occur only when those nations pretending to aspire to the heights of contemporary, cultural endeavor decide, without regard to national rivalry, upon common measures. In order to secure decisive scientific results, we require a series of simultaneous expeditions whose aims must be, through dispersal over several points of the Arctic region and using identical instruments in line with identical instructions, to conduct a simultaneous, year-long series of observations. Only thereby shall we acquire the material for solutions to those great problems of nature that reside in the Arctic ice, and only then shall we earn the reward for those considerable resources that have hitherto been squandered in labor, endeavor, deprivation, and money in the polar region.