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Sample records for 3-d magnetic resonance

  1. 3-D Display Of Magnetic Resonance Imaging Of The Spine

    NASA Astrophysics Data System (ADS)

    Nelson, Alan C.; Kim, Yongmin; Haralick, Robert M.; Anderson, Paul A.; Johnson, Roger H.; DeSoto, Larry A.

    1988-06-01

    The original data is produced through standard magnetic resonance imaging (MRI) procedures with a surface coil applied to the lower back of a normal human subject. The 3-D spine image data consists of twenty-six contiguous slices with 256 x 256 pixels per slice. Two methods for visualization of the 3-D spine are explored. One method utilizes a verifocal mirror system which creates a true 3-D virtual picture of the object. Another method uses a standard high resolution monitor to simultaneously show the three orthogonal sections which intersect at any user-selected point within the object volume. We discuss the application of these systems in assessment of low back pain.

  2. Unsupervised fuzzy segmentation of 3D magnetic resonance brain images

    NASA Astrophysics Data System (ADS)

    Velthuizen, Robert P.; Hall, Lawrence O.; Clarke, Laurence P.; Bensaid, Amine M.; Arrington, J. A.; Silbiger, Martin L.

    1993-07-01

    Unsupervised fuzzy methods are proposed for segmentation of 3D Magnetic Resonance images of the brain. Fuzzy c-means (FCM) has shown promising results for segmentation of single slices. FCM has been investigated for volume segmentations, both by combining results of single slices and by segmenting the full volume. Different strategies and initializations have been tried. In particular, two approaches have been used: (1) a method by which, iteratively, the furthest sample is split off to form a new cluster center, and (2) the traditional FCM in which the membership grade matrix is initialized in some way. Results have been compared with volume segmentations by k-means and with two supervised methods, k-nearest neighbors and region growing. Results of individual segmentations are presented as well as comparisons on the application of the different methods to a number of tumor patient data sets.

  3. Fast 3D fluid registration of brain magnetic resonance images

    NASA Astrophysics Data System (ADS)

    Leporé, Natasha; Chou, Yi-Yu; Lopez, Oscar L.; Aizenstein, Howard J.; Becker, James T.; Toga, Arthur W.; Thompson, Paul M.

    2008-03-01

    Fluid registration is widely used in medical imaging to track anatomical changes, to correct image distortions, and to integrate multi-modality data. Fluid mappings guarantee that the template image deforms smoothly into the target, without tearing or folding, even when large deformations are required for accurate matching. Here we implemented an intensity-based fluid registration algorithm, accelerated by using a filter designed by Bro-Nielsen and Gramkow. We validated the algorithm on 2D and 3D geometric phantoms using the mean square difference between the final registered image and target as a measure of the accuracy of the registration. In tests on phantom images with different levels of overlap, varying amounts of Gaussian noise, and different intensity gradients, the fluid method outperformed a more commonly used elastic registration method, both in terms of accuracy and in avoiding topological errors during deformation. We also studied the effect of varying the viscosity coefficients in the viscous fluid equation, to optimize registration accuracy. Finally, we applied the fluid registration algorithm to a dataset of 2D binary corpus callosum images and 3D volumetric brain MRIs from 14 healthy individuals to assess its accuracy and robustness.

  4. GPU-accelerated denoising of 3D magnetic resonance images

    SciTech Connect

    Howison, Mark; Wes Bethel, E.

    2014-05-29

    The raw computational power of GPU accelerators enables fast denoising of 3D MR images using bilateral filtering, anisotropic diffusion, and non-local means. In practice, applying these filtering operations requires setting multiple parameters. This study was designed to provide better guidance to practitioners for choosing the most appropriate parameters by answering two questions: what parameters yield the best denoising results in practice? And what tuning is necessary to achieve optimal performance on a modern GPU? To answer the first question, we use two different metrics, mean squared error (MSE) and mean structural similarity (MSSIM), to compare denoising quality against a reference image. Surprisingly, the best improvement in structural similarity with the bilateral filter is achieved with a small stencil size that lies within the range of real-time execution on an NVIDIA Tesla M2050 GPU. Moreover, inappropriate choices for parameters, especially scaling parameters, can yield very poor denoising performance. To answer the second question, we perform an autotuning study to empirically determine optimal memory tiling on the GPU. The variation in these results suggests that such tuning is an essential step in achieving real-time performance. These results have important implications for the real-time application of denoising to MR images in clinical settings that require fast turn-around times.

  5. Combined registration of 3D tibia and femur implant models in 3D magnetic resonance images

    NASA Astrophysics Data System (ADS)

    Englmeier, Karl-Hans; Siebert, Markus; von Eisenhart-Rothe, Ruediger; Graichen, Heiko

    2008-03-01

    The most frequent reasons for revision of total knee arthroplasty are loosening and abnormal axial alignment leading to an unphysiological kinematic of the knee implant. To get an idea about the postoperative kinematic of the implant, it is essential to determine the position and orientation of the tibial and femoral prosthesis. Therefore we developed a registration method for fitting 3D CAD-models of knee joint prostheses into an 3D MR image. This rigid registration is the basis for a quantitative analysis of the kinematics of knee implants. Firstly the surface data of the prostheses models are converted into a voxel representation; a recursive algorithm determines all boundary voxels of the original triangular surface data. Secondly an initial preconfiguration of the implants by the user is still necessary for the following step: The user has to perform a rough preconfiguration of both remaining prostheses models, so that the fine matching process gets a reasonable starting point. After that an automated gradient-based fine matching process determines the best absolute position and orientation: This iterative process changes all 6 parameters (3 rotational- and 3 translational parameters) of a model by a minimal amount until a maximum value of the matching function is reached. To examine the spread of the final solutions of the registration, the interobserver variability was measured in a group of testers. This variability, calculated by the relative standard deviation, improved from about 50% (pure manual registration) to 0.5% (rough manual preconfiguration and subsequent fine registration with the automatic fine matching process).

  6. Quantitative 3D magnetic resonance elastography: Comparison with dynamic mechanical analysis

    PubMed Central

    Rossman, Phillip J.; Arani, Arvin; Lake, David S.; Glaser, Kevin J.; Trzasko, Joshua D.; Manduca, Armando; McGee, Kiaran P.; Ehman, Richard L.; Araoz, Philip A.

    2016-01-01

    Purpose Magnetic resonance elastography (MRE) is a rapidly growing noninvasive imaging technique for measuring tissue mechanical properties in vivo. Previous studies have compared two‐dimensional MRE measurements with material properties from dynamic mechanical analysis (DMA) devices that were limited in frequency range. Advanced DMA technology now allows broad frequency range testing, and three‐dimensional (3D) MRE is increasingly common. The purpose of this study was to compare 3D MRE stiffness measurements with those of DMA over a wide range of frequencies and shear stiffnesses. Methods 3D MRE and DMA were performed on eight different polyvinyl chloride samples over 20–205 Hz with stiffness between 3 and 23 kPa. Driving frequencies were chosen to create 1.1, 2.2, 3.3, 4.4, 5.5, and 6.6 effective wavelengths across the diameter of the cylindrical phantoms. Wave images were analyzed using direct inversion and local frequency estimation algorithm with the curl operator and compared with DMA measurements at each corresponding frequency. Samples with sufficient spatial resolution and with an octahedral shear strain signal‐to‐noise ratio > 3 were compared. Results Consistency between the two techniques was measured with the intraclass correlation coefficient (ICC) and was excellent with an overall ICC of 0.99. Conclusions 3D MRE and DMA showed excellent consistency over a wide range of frequencies and stiffnesses. Magn Reson Med 77:1184–1192, 2017. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. PMID:27016276

  7. Quiescence of magnetic braking and control of 3D non-resonance in KSTAR

    NASA Astrophysics Data System (ADS)

    Park, J.-K.; in, Y.; Jeon, Y. M.; Logan, N. C.; Wang, Z. R.; Menard, J. E.; Kim, J. H.; Ko, W. H.; Kstar Team

    2016-10-01

    Magnetic braking using non-axisymmetric (3D) field is a promising tool to control rotation in tokamaks and thereby micro-to-macro instabilities. Ideally magnetic braking should induce only neoclassical momentum transport, without provoking resonant instabilities or unnecessary perturbations in particle or heat transport. Indeed in KSTAR, it was shown that the 3 rows of internal coils could be used to generate highly non-resonant n =1 with backward-helicity field distribution, called -90 phasing, and to change rotation without any perturbations to other transport channels. Recent KSTAR experiments, however, have also shown that the broad-wavelength field distribution, called 0 phasing, is rather more quiescent whereas -90 phasing can be highly degrading especially in high q95 plasmas. IPEC and NTV modeling are consistent with both observations, and further provide the optimal point in coil phasing and amplitude space. Additional experiments and comparisons with modeling all imply the sensitivity of plasma response to remnant resonant field, and thus importance of non-resonance control, to accomplish quiescent magnetic braking. This work was supported by DOE Contract DE-AC02-09CH11466.

  8. Effect of Resonant Magnetic Perturbations on 3D equilibria in the MST RFP

    NASA Astrophysics Data System (ADS)

    Munaretto, Stefano

    2015-11-01

    The orientation of 3D, stellarator-like equilibria in the MST RFP can now be controlled with application of an m = 1 RMP. This has led to greatly improved diagnosis, revealing enhancements in both the central electron temperature and density. Coupled to a recent advance in the V3FIT code, reconstructions of the 3D equilibria have also been dramatically improved. The RMP also inhibits the generation of high-energy >20 keV electrons that is otherwise common with the 3D state. This state occurs when the normally broad spectrum of core-resonant m = 1 tearing modes condenses, with the innermost resonant mode growing to large amplitude, reaching ~ 8% of the axisymmetric field strength. This occurs in plasmas of sufficiently large Lundquist number ~ IpTe3/2, and the duration of the state is maximized with zero applied Bt (infinite toroidal beta). As the dominant mode grows, eddy current in MST's conducting shell slows the mode's rotation. This leads to locking of the 3D structure, but with an orientation that varies randomly shot to shot, making diagnosis difficult. An m = 1 RMP can now be applied with an array of saddle coils at the vertical insulated cut in the shell. With an amplitude br/B ~ 10% and a tailored temporal waveform, the RMP can force the 3D structure into any desired orientation relative to MST's diagnostics. A recent advance in V3FIT allows calculation of the substantial helical image current flowing in MST's shell, which has in turn allowed self-consistent utilization of both external and internal (Faraday rotation) measurements of the magnetic field. The ORBIT code predicts reduced stochasticity and improved confinement of high-energy electrons within the 3D structure. The suppression of these electrons by the m = 1 RMP may reflect a change to the central magnetic topology. The generation of these electrons is unaffected by non-resonant perturbations, such as m = 3. Supported by the US DOE.

  9. Evaluation of Gastric Volumes: Comparison of 3-D Ultrasound and Magnetic Resonance Imaging.

    PubMed

    Buisman, Wijnand J; Mauritz, Femke A; Westerhuis, Wouter E; Gilja, Odd Helge; van der Zee, David C; van Herwaarden-Lindeboom, Maud Y A

    2016-07-01

    To investigate gastric accommodation, accurate measurements of gastric volumes are necessary. An excellent technique to measure gastric volumes is dynamic magnetic resonance imaging (MRI). Unfortunately, dynamic MRI is expensive and not always available. A new 3-D ultrasound (US) method using a matrix transducer was developed to measure gastric volumes. In this prospective study, 14 healthy volunteers underwent a dynamic MRI and a 3-D US. Gastric volumes were calculated with intra-gastric liquid content and total gastric volume. Mean postprandial liquid gastric content was 397 ± 96.5 mL. Mean volume difference was 1.0 mL with limits of agreement of -8.9 to 10.9 mL. When gastric air was taken into account, mean total gastric volume was 540 ± 115.4 mL SD. Mean volume difference was 2.3 mL with limits of agreement of -21.1 to 26.4 mL. The matrix 3-D US showed excellent agreement with dynamic MRI. Therefore matrix 3-D US is a reliable alternative to measure gastric volumes.

  10. Treatment envelope evaluation in transcranial magnetic resonance-guided focused ultrasound utilizing 3D MR thermometry

    PubMed Central

    2014-01-01

    Background Current clinical targets for transcranial magnetic resonance-guided focused ultrasound (tcMRgFUS) are all located close to the geometric center of the skull convexity, which minimizes challenges related to focusing the ultrasound through the skull bone. Non-central targets will have to be reached to treat a wider variety of neurological disorders and solid tumors. Treatment envelope studies utilizing two-dimensional (2D) magnetic resonance (MR) thermometry have previously been performed to determine the regions in which therapeutic levels of FUS can currently be delivered. Since 2D MR thermometry was used, very limited information about unintended heating in near-field tissue/bone interfaces could be deduced. Methods In this paper, we present a proof-of-concept treatment envelope study with three-dimensional (3D) MR thermometry monitoring of FUS heatings performed in a phantom and a lamb model. While the moderate-sized transducer used was not designed for transcranial geometries, the 3D temperature maps enable monitoring of the entire sonication field of view, including both the focal spot and near-field tissue/bone interfaces, for full characterization of all heating that may occur. 3D MR thermometry is achieved by a combination of k-space subsampling and a previously described temporally constrained reconstruction method. Results We present two different types of treatment envelopes. The first is based only on the focal spot heating—the type that can be derived from 2D MR thermometry. The second type is based on the relative near-field heating and is calculated as the ratio between the focal spot heating and the near-field heating. This utilizes the full 3D MR thermometry data achieved in this study. Conclusions It is shown that 3D MR thermometry can be used to improve the safety assessment in treatment envelope evaluations. Using a non-optimal transducer, it is shown that some regions where therapeutic levels of FUS can be delivered, as suggested by

  11. 3D mapping of neuronal migration in the embryonic mouse brain with magnetic resonance microimaging.

    PubMed

    Deans, Abby E; Wadghiri, Youssef Zaim; Aristizábal, Orlando; Turnbull, Daniel H

    2015-07-01

    A prominent feature of the developing mammalian brain is the widespread migration of neural progenitor (NP) cells during embryogenesis. A striking example is provided by NP cells born in the ventral forebrain of mid-gestation stage mice, which subsequently migrate long distances to their final positions in the cortex and olfactory bulb. Previous studies have used two-dimensional histological methods, making it difficult to analyze three-dimensional (3D) migration patterns. Unlike histology, magnetic resonance microimaging (micro-MRI) is a non-destructive, quantitative and inherently 3D imaging method for analyzing mouse embryos. To allow mapping of migrating NP cells with micro-MRI, cells were labeled in situ in the medial (MGE) and lateral (LGE) ganglionic eminences, using targeted in utero ultrasound-guided injection of micron-sized particles of iron-oxide (MPIO). Ex vivo micro-MRI and histology were then performed 5-6days after injection, demonstrating that the MPIO had magnetically labeled the migrating NP populations, which enabled 3D visualization and automated segmentation of the labeled cells. This approach was used to analyze the distinct patterns of migration from the MGE and LGE, and to construct rostral-caudal migration maps from each progenitor region. Furthermore, abnormal migratory phenotypes were observed in Nkx2.1(-/-) embryos, most notably a significant increase in cortical neurons derived from the Nkx2.1(-/-) LGE. Taken together, these results demonstrate that MPIO labeling and micro-MRI provide an efficient and powerful approach for analyzing 3D cell migration patterns in the normal and mutant mouse embryonic brain.

  12. 3D kinematics of the tarsal joints from magnetic resonance images

    NASA Astrophysics Data System (ADS)

    Hirsch, Bruce E.; Udupa, Jayaram K.; Okereke, Enyi; Hillstrom, Howard J.; Siegler, Sorin; Ringleb, Stacie I.; Imhauser, Carl W.

    2001-09-01

    We have developed a method for analyzing motion at skeletal joints based on the 3D reconstruction of magnetic resonance (MR) image data. Since the information about each voxel in MR images includes its location in the scanner, it follows that information is available for each organ whose 3D surface is computed from a series of MR slices. In addition, there is information on the shape and orientation of each organ, and the contact areas of adjacent bones. By collecting image data in different positions we can calculate the motion of the individual bones. We have used this method to study human foot bones, in order to understand normal and abnormal foot function. It has been used to evaluate patients with tarsal coalitions, various forms of pes planus, ankle sprains, and several other conditions. A newly described feature of this system is the ability to visualize the contact area at a joint, as determined by the region of minimum distance. The display of contact area helps understand abnormal joint function. Also, the use of 3D imaging reveals motions in joints which cannot otherwise be visualized, such as the subtalar joint, for more accurate diagnosis of joint injury.

  13. Anatomical delineation of congenital heart disease using 3D magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Adams Bornemeier, Renee; Fellows, Kenneth E.; Fogel, Mark A.; Weinberg, Paul M.

    1994-05-01

    Anatomic delineation of the heart and great vessels is a necessity when managing children with congenital heart disease. Spatial orientation of the vessels and chambers in the heart and the heart itself may be quite abnormal. Though magnetic resonance imaging provides a noninvasive means for determining the anatomy, the intricate interrelationships between many structures are difficult to conceptualize from a 2-D format. Taking the 2-D images and using a volumetric analysis package allows for a 3-D replica of the heart to be created. This model can then be used to view the anatomy and spatial arrangement of the cardiac structures. This information may be utilized by the physicians to assist in the clinical management of these children.

  14. Denoising of 3D magnetic resonance images by using higher-order singular value decomposition.

    PubMed

    Zhang, Xinyuan; Xu, Zhongbiao; Jia, Nan; Yang, Wei; Feng, Qianjin; Chen, Wufan; Feng, Yanqiu

    2015-01-01

    The denoising of magnetic resonance (MR) images is important to improve the inspection quality and reliability of quantitative image analysis. Nonlocal filters by exploiting similarity and/or sparseness among patches or cubes achieve excellent performance in denoising MR images. Recently, higher-order singular value decomposition (HOSVD) has been demonstrated to be a simple and effective method for exploiting redundancy in the 3D stack of similar patches during denoising 2D natural image. This work aims to investigate the application and improvement of HOSVD to denoising MR volume data. The wiener-augmented HOSVD method achieves comparable performance to that of BM4D. For further improvement, we propose to augment the standard HOSVD stage by a second recursive stage, which is a repeated HOSVD filtering of the weighted summation of the residual and denoised image in the first stage. The appropriate weights have been investigated by experiments with different image types and noise levels. Experimental results over synthetic and real 3D MR data demonstrate that the proposed method outperforms current state-of-the-art denoising methods.

  15. Focused shape models for hip joint segmentation in 3D magnetic resonance images.

    PubMed

    Chandra, Shekhar S; Xia, Ying; Engstrom, Craig; Crozier, Stuart; Schwarz, Raphael; Fripp, Jurgen

    2014-04-01

    Deformable models incorporating shape priors have proved to be a successful approach in segmenting anatomical regions and specific structures in medical images. This paper introduces weighted shape priors for deformable models in the context of 3D magnetic resonance (MR) image segmentation of the bony elements of the human hip joint. The fully automated approach allows the focusing of the shape model energy to a priori selected anatomical structures or regions of clinical interest by preferentially ordering the shape representation (or eigen-modes) within this type of model to the highly weighted areas. This focused shape model improves accuracy of the shape constraints in those regions compared to standard approaches. The proposed method achieved femoral head and acetabular bone segmentation mean absolute surface distance errors of 0.55±0.18mm and 0.75±0.20mm respectively in 35 3D unilateral MR datasets from 25 subjects acquired at 3T with different limited field of views for individual bony components of the hip joint.

  16. Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance

    PubMed Central

    Varghese, Anitha; Yee, Michael S; Chan, Cheuk F; Crowe, Lindsey A; Keenan, Niall G; Johnston, Desmond G; Pennell, Dudley J

    2009-01-01

    Background There is recent evidence suggesting that rosiglitazone increases death from cardiovascular causes. We investigated the direct effect of this drug on atheroma using 3D carotid cardiovascular magnetic resonance. Results A randomized, placebo-controlled, double-blind study was performed to evaluate the effect of rosiglitazone treatment on carotid atherosclerosis in subjects with type 2 diabetes and coexisting vascular disease or hypertension. The primary endpoint of the study was the change from baseline to 52 weeks of carotid arterial wall volume, reflecting plaque burden, as measured by carotid cardiovascular magnetic resonance. Rosiglitazone or placebo was allocated to 28 and 29 patients respectively. Patients were managed to have equivalent glycemic control over the study period, but in fact the rosiglitazone group lowered their HbA1c by 0.88% relative to placebo (P < 0.001). Most patients received a statin or fibrate as lipid control medication (rosiglitazone 78%, controls 83%). Data are presented as mean ± SD. At baseline, the carotid arterial wall volume in the placebo group was 1146 ± 550 mm3 and in the rosiglitazone group was 1354 ± 532 mm3. After 52 weeks, the respective volumes were 1134 ± 523 mm3 and 1348 ± 531 mm3. These changes (-12.1 mm3 and -5.7 mm3 in the placebo and rosiglitazone groups, respectively) were not statistically significant between groups (P = 0.57). Conclusion Treatment with rosiglitazone over 1 year had no effect on progression of carotid atheroma in patients with type 2 diabetes mellitus compared to placebo. PMID:19635160

  17. Relevance of 3D magnetic resonance imaging sequences in diagnosing basal subarachnoid neurocysticercosis.

    PubMed

    Carrillo Mezo, Roger; Lara García, Javier; Arroyo, Mariana; Fleury, Agnès

    2015-12-01

    Imagenological diagnosis of subarachnoid neurocysticercosis is usually difficult when classical magnetic resonance imaging (MRI) sequences are used. The purpose of this study was to evaluate the advantages of 3D MRI sequences (Fast Imaging Employing Steady-state Acquisition (FIESTA) and Spoiled Gradient Recalled Echo (SPGR)) with respect to classical sequences (Fluid Attenuation Inversion Recovery (FLAIR) and T1) in visualizing Taenia solium cyst in these locations. Forty-seven T. solium cysts located in the basal cisterns of the subarachnoid space were diagnosed in eighteen Mexican patients. A pre-treatment MRI was performed on all patients, and all four sequences (FIESTA, FLAIR, T1 SPGR, and T2) were evaluated independently by two neuroradiologists. The sensitivity of each sequence to detect the parasite membrane and scolex was evaluated, along with its capacity to detect differences in signal intensity between cerebrospinal fluid (CSF) and cysts. FIESTA sequences allowed the visualization of cyst membrane in 87.2% of the parasites evaluated, FLAIR in 38.3%, SPGR in 23.4%, and T2 in 17.0%. The superiority of FIESTA sequences over the other three imaging methods was statistically significant (P<0.001). Scolices were detected by FIESTA twice as much as the other sequences did, although this difference was not significant (P>0.05). Differences in signal intensity between CSF and parasite cysts were significant in FIESTA (P<0.0001), SPGR (P<0.0001), and FLAIR (P=0.005) sequences. For the first time, the usefulness of 3D MRI sequences to diagnose T. solium cysts located in the basal cisterns of the subarachnoid space was demonstrated. The routine use of these sequences could favor an earlier diagnosis and greatly improve the prognosis of patients affected by this severe form of the disease.

  18. 4D Magnetic Resonance Velocimetry in a 3D printed brain aneurysm

    NASA Astrophysics Data System (ADS)

    Amili, Omid; Schiavazzi, Daniele; Coletti, Filippo

    2016-11-01

    Cerebral aneurysms are of great clinical importance. It is believed that hemodynamics play a critical role in the development, growth, and rupture of brain arteries with such condition. The flow structure in the aneurysm sac is complex, unsteady, and three-dimensional. Therefore the time-resolved measurement of the three-dimensional three-component velocity field is crucial to predict the clinical outcome. In this study magnetic resonance velocimetry is used to assess the fluid dynamics inside a 3D printed model of a giant intracranial aneurysm. We reach sub-millimeter resolution while resolving sixteen instances within the cardiac cycle. The physiological flow waveform is imposed using an in-house built pump in a flow circuit where the cardiovascular impedance is matched. The flow evolution over time is reconstructed in detail. The complex flow structure is characterized by vortical and helical motions that reside in the aneurysm for most part of the cycle. The 4D pressured distribution is also reconstructed from the velocity field. The present case study was used in a previous CFD challenge, therefore these results may provide useful experimental comparison for simulations performed by other research groups.

  19. Craniosynostosis: prenatal diagnosis by 2D/3D ultrasound, magnetic resonance imaging and computed tomography.

    PubMed

    Helfer, Talita Micheletti; Peixoto, Alberto Borges; Tonni, Gabriele; Araujo Júnior, Edward

    2016-09-01

    Craniosynostosis is defined as the process of premature fusion of one or more of the cranial sutures. It is a common condition that occurs in about 1 to 2,000 live births. Craniosynostosis may be classified in primary or secondary. It is also classified as nonsyndromic or syndromic. According to suture commitment, craniosynostosis may affect a single suture or multiple sutures. There is a wide range of syndromes involving craniosynostosis and the most common are Apert, Pffeifer, Crouzon, Shaethre-Chotzen and Muenke syndromes. The underlying etiology of nonsyndromic craniosynostosis is unknown. Mutations in the fibroblast growth factor (FGF) signalling pathway play a crucial role in the etiology of craniosynostosis syndromes. Prenatal ultrasound`s detection rate of craniosynostosis is low. Nowadays, different methods can be applied for prenatal diagnosis of craniosynostosis, such as two-dimensional (2D) and three-dimensional (3D) ultrasound, magnetic resonance imaging (MRI), computed tomography (CT) scan and, finally, molecular diagnosis. The presence of craniosynostosis may affect the birthing process. Fetuses with craniosynostosis also have higher rates of perinatal complications. In order to avoid the risks of untreated craniosynostosis, children are usually treated surgically soon after postnatal diagnosis.

  20. Testing the Validity of the Neoclassical Toroidal Viscosity Model of Torque due to 3D Non-Resonant Magnetic Fields

    NASA Astrophysics Data System (ADS)

    McCubbin, A. J.; Smith, S. P.; Ferraro, N. M.; Callen, J. D.; Meneghini, O.

    2012-10-01

    Understanding the torque applied by resonant and non-resonant magnetic perturbations and its effect on rotation is essential to predict confinement and stability in burning plasmas. Non-axisymmetric 3D fields produced in the DIII-D tokamak apply a torque to the plasma, which can be evaluated through its effect on the plasma rotation. One explanation for this torque is Neoclassical Toroidal Viscosity (NTV) acting through non-resonant field components [1]. We have developed a software framework in which magnetic perturbations calculated by the state of the art two fluid MHD code M3D-C1 can be used in NTV calculations. For discharges with applied external magnetic fields in DIII-D, the experimentally determined torques will be analyzed and compared with NTV models.[4pt] [1] J.D. Callen, Nucl. Fusion 51, 094026 (2011).

  1. Advancement of 31P Magnetic Resonance Spectroscopy Using GRAPPA Reconstruction on a 3D Volume

    NASA Astrophysics Data System (ADS)

    Clevenger, Tony

    The overall objective of this research is to improve currently available metabolic imaging techniques for clinical use in monitoring and predicting treatment response to radiation therapy in liver cancer. Liver metabolism correlates with inflammatory and neoplastic liver diseases, which alter the intracellular concentration of phosphorus- 31 (31P) metabolites [1]. It is assumed that such metabolic changes occur prior to physical changes of the tissue. Therefore, information on regional changes of 31P metabolites in the liver, obtained by Magnetic Resonance Spectroscopic Imaging (MRSI) [1,2], can help in diagnosis and follow-up of various liver diseases. Specifically, there appears to be an immediate need of this technology for both the assessment of tumor response in patients with Hepatocellular Carcinoma (HCC) treated with Stereotactic Body Radiation Therapy (SBRT) [3--5], as well as assessment of radiation toxicity, which can result in worsening liver dysfunction [6]. Pilot data from our lab has shown that 31P MRSI has the potential to identify treatment response five months sooner than conventional methods [7], and to assess the biological response of liver tissue to radiation 24 hours post radiation therapy [8]. While this data is very promising, commonly occurring drawbacks for 31P MRSI are patient discomfort due to long scan times and prone positioning within the scanner, as well as reduced data quality due to patient motion and respiration. To further advance the full potential of 31P MRSI as a clinical diagnostic tool in the management of liver cancer, this PhD research project had the following aims: I) Reduce the long acquisition time of 3D 31P MRS by formulating and imple- menting an appropriate GRAPPA undersampling scheme and reconstruction on a clinical MRI scanner II) Testing and quantitative validation of GRAPPA reconstruction on 3D 31P MRSI on developmental phantoms and healthy volunteers At completion, this work should considerably advance 31P MRSI

  2. Breast Density Analysis with Automated Whole-Breast Ultrasound: Comparison with 3-D Magnetic Resonance Imaging.

    PubMed

    Chen, Jeon-Hor; Lee, Yan-Wei; Chan, Si-Wa; Yeh, Dah-Cherng; Chang, Ruey-Feng

    2016-05-01

    In this study, a semi-automatic breast segmentation method was proposed on the basis of the rib shadow to extract breast regions from 3-D automated whole-breast ultrasound (ABUS) images. The density results were correlated with breast density values acquired with 3-D magnetic resonance imaging (MRI). MRI images of 46 breasts were collected from 23 women without a history of breast disease. Each subject also underwent ABUS. We used Otsu's thresholding method on ABUS images to obtain local rib shadow information, which was combined with the global rib shadow information (extracted from all slice projections) and integrated with the anatomy's breast tissue structure to determine the chest wall line. The fuzzy C-means classifier was used to extract the fibroglandular tissues from the acquired images. Whole-breast volume (WBV) and breast percentage density (BPD) were calculated in both modalities. Linear regression was used to compute the correlation of density results between the two modalities. The consistency of density measurement was also analyzed on the basis of intra- and inter-operator variation. There was a high correlation of density results between MRI and ABUS (R(2) = 0.798 for WBV, R(2) = 0.825 for PBD). The mean WBV from ABUS images was slightly smaller than the mean WBV from MR images (MRI: 342.24 ± 128.08 cm(3), ABUS: 325.47 ± 136.16 cm(3), p < 0.05). In addition, the BPD calculated from MR images was smaller than the BPD from ABUS images (MRI: 24.71 ± 15.16%, ABUS: 28.90 ± 17.73%, p < 0.05). The intra-operator and inter-operator variant analysis results indicated that there was no statistically significant difference in breast density measurement variation between the two modalities. Our results revealed a high correlation in WBV and BPD between MRI and ABUS. Our study suggests that ABUS provides breast density information useful in the assessment of breast health.

  3. Analysis of 3-D Tongue Motion from Tagged and Cine Magnetic Resonance Images

    ERIC Educational Resources Information Center

    Xing, Fangxu; Woo, Jonghye; Lee, Junghoon; Murano, Emi Z.; Stone, Maureen; Prince, Jerry L.

    2016-01-01

    Purpose: Measuring tongue deformation and internal muscle motion during speech has been a challenging task because the tongue deforms in 3 dimensions, contains interdigitated muscles, and is largely hidden within the vocal tract. In this article, a new method is proposed to analyze tagged and cine magnetic resonance images of the tongue during…

  4. 3D-FIESTA Magnetic Resonance Angiography Fusion Imaging of Distal Segment of Occluded Middle Cerebral Artery.

    PubMed

    Kuribara, Tomoyoshi; Haraguchi, Koichi; Ogane, Kazumi; Matsuura, Nobuki; Ito, Takeo

    2015-01-01

    Middle cerebral artery (MCA) occlusion was examined with basi-parallel anatomical scanning (BPAS) using three-dimensional fast imaging employing steady-state acquisition (3D-FIESTA), and 3D-FIESTA and magnetic resonance angiography (MRA) fusion images were created. We expected that an incidence of hemorrhagic complications due to vessel perforations would be decreased by obtaining vascular information beyond the occlusion and thus acute endovascular revascularization could be performed using such techniques. We performed revascularization for acute MCA occlusion for five patients who were admitted in our hospital from October 2012 to October 2014. Patients consisted of 1 man and 4 women with a mean age of 76.2 years (range: 59-86 years). Fusion images were created from three-dimensional time of flight (3D-TOF) MRA and 3D-FIESTA with phase cycling (3D-FIESTA-C). Then thrombectomy was performed in all the 5 patients. Merci retriever to 1 patient, Penumbra system to 1, urokinase infusion to 2, and Solitaire to 1 using such techniques. In all cases, a 3D-FIESTA-MRA fusion imaging could depict approximately clear vascular information to at least the M3 segment beyond the occlusion. And each acute revascularization was able to perform smoothly using these imaging techniques. In all cases, there was no symptomatic hemorrhagic complication. It showed that 3D-FIESTA MRA fusion imaging technique could obtain vascular information beyond the MCA occlusion. In this study, no symptomatic hemorrhagic complications were detected. It could imply that such techniques were useful not only to improve treatment efficiency but also to reduce the risk of development of hemorrhagic complications caused by vessel perforations in acute revascularization.

  5. A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance.

    PubMed

    Fair, Merlin J; Gatehouse, Peter D; DiBella, Edward V R; Firmin, David N

    2015-08-01

    A comprehensive review is undertaken of the methods available for 3D whole-heart first-pass perfusion (FPP) and their application to date, with particular focus on possible acceleration techniques. Following a summary of the parameters typically desired of 3D FPP methods, the review explains the mechanisms of key acceleration techniques and their potential use in FPP for attaining 3D acquisitions. The mechanisms include rapid sequences, non-Cartesian k-space trajectories, reduced k-space acquisitions, parallel imaging reconstructions and compressed sensing. An attempt is made to explain, rather than simply state, the varying methods with the hope that it will give an appreciation of the different components making up a 3D FPP protocol. Basic estimates demonstrating the required total acceleration factors in typical 3D FPP cases are included, providing context for the extent that each acceleration method can contribute to the required imaging speed, as well as potential limitations in present 3D FPP literature. Although many 3D FPP methods are too early in development for the type of clinical trials required to show any clear benefit over current 2D FPP methods, the review includes the small but growing quantity of clinical research work already using 3D FPP, alongside the more technical work. Broader challenges concerning FPP such as quantitative analysis are not covered, but challenges with particular impact on 3D FPP methods, particularly with regards to motion effects, are discussed along with anticipated future work in the field.

  6. Integration of 3D 1H-magnetic resonance spectroscopy data into neuronavigation systems for tumor biopsies

    NASA Astrophysics Data System (ADS)

    Kanberoglu, Berkay; Moore, Nina Z.; Frakes, David; Karam, Lina J.; Debbins, Josef P.; Preul, Mark C.

    2013-03-01

    Many important applications in clinical medicine can benefit from the fusion of spectroscopy data with anatomical images. For example, the correlation of metabolite profiles with specific regions of interest in anatomical tumor images can be useful in characterizing and treating heterogeneous tumors that appear structurally homogeneous. Such applications can build on the correlation of data from in-vivo Proton Magnetic Resonance Spectroscopy Imaging (1HMRSI) with data from genetic and ex-vivo Nuclear Magnetic Resonance spectroscopy. To establish that correlation, tissue samples must be neurosurgically extracted from specifically identified locations with high accuracy. Toward that end, this paper presents new neuronavigation technology that enhances current clinical capabilities in the context of neurosurgical planning and execution. The proposed methods improve upon the current state-of-the-art in neuronavigation through the use of detailed three dimensional (3D) 1H-MRSI data. MRSI spectra are processed and analyzed, and specific voxels are selected based on their chemical contents. 3D neuronavigation overlays are then generated and applied to anatomical image data in the operating room. Without such technology, neurosurgeons must rely on memory and other qualitative resources alone for guidance in accessing specific MRSI-identified voxels. In contrast, MRSI-based overlays provide quantitative visual cues and location information during neurosurgery. The proposed methods enable a progressive new form of online MRSI-guided neuronavigation that we demonstrate in this study through phantom validation and clinical application.

  7. Quantitative 3D Analysis of Plant Roots Growing in Soil Using Magnetic Resonance Imaging1[OPEN

    PubMed Central

    Kochs, Johannes; Pflugfelder, Daniel

    2016-01-01

    Precise measurements of root system architecture traits are an important requirement for plant phenotyping. Most of the current methods for analyzing root growth require either artificial growing conditions (e.g. hydroponics), are severely restricted in the fraction of roots detectable (e.g. rhizotrons), or are destructive (e.g. soil coring). On the other hand, modalities such as magnetic resonance imaging (MRI) are noninvasive and allow high-quality three-dimensional imaging of roots in soil. Here, we present a plant root imaging and analysis pipeline using MRI together with an advanced image visualization and analysis software toolbox named NMRooting. Pots up to 117 mm in diameter and 800 mm in height can be measured with the 4.7 T MRI instrument used here. For 1.5 l pots (81 mm diameter, 300 mm high), a fully automated system was developed enabling measurement of up to 18 pots per day. The most important root traits that can be nondestructively monitored over time are root mass, length, diameter, tip number, and growth angles (in two-dimensional polar coordinates) and spatial distribution. Various validation measurements for these traits were performed, showing that roots down to a diameter range between 200 μm and 300 μm can be quantitatively measured. Root fresh weight correlates linearly with root mass determined by MRI. We demonstrate the capabilities of MRI and the dedicated imaging pipeline in experimental series performed on soil-grown maize (Zea mays) and barley (Hordeum vulgare) plants. PMID:26729797

  8. Quantitative 3D Analysis of Plant Roots Growing in Soil Using Magnetic Resonance Imaging.

    PubMed

    van Dusschoten, Dagmar; Metzner, Ralf; Kochs, Johannes; Postma, Johannes A; Pflugfelder, Daniel; Bühler, Jonas; Schurr, Ulrich; Jahnke, Siegfried

    2016-03-01

    Precise measurements of root system architecture traits are an important requirement for plant phenotyping. Most of the current methods for analyzing root growth require either artificial growing conditions (e.g. hydroponics), are severely restricted in the fraction of roots detectable (e.g. rhizotrons), or are destructive (e.g. soil coring). On the other hand, modalities such as magnetic resonance imaging (MRI) are noninvasive and allow high-quality three-dimensional imaging of roots in soil. Here, we present a plant root imaging and analysis pipeline using MRI together with an advanced image visualization and analysis software toolbox named NMRooting. Pots up to 117 mm in diameter and 800 mm in height can be measured with the 4.7 T MRI instrument used here. For 1.5 l pots (81 mm diameter, 300 mm high), a fully automated system was developed enabling measurement of up to 18 pots per day. The most important root traits that can be nondestructively monitored over time are root mass, length, diameter, tip number, and growth angles (in two-dimensional polar coordinates) and spatial distribution. Various validation measurements for these traits were performed, showing that roots down to a diameter range between 200 μm and 300 μm can be quantitatively measured. Root fresh weight correlates linearly with root mass determined by MRI. We demonstrate the capabilities of MRI and the dedicated imaging pipeline in experimental series performed on soil-grown maize (Zea mays) and barley (Hordeum vulgare) plants.

  9. 3-D residual eddy current field characterisation: applied to diffusion weighted magnetic resonance imaging.

    PubMed

    O'Brien, Kieran; Daducci, Alessandro; Kickler, Nils; Lazeyras, Francois; Gruetter, Rolf; Feiweier, Thorsten; Krueger, Gunnar

    2013-08-01

    Clinical use of the Stejskal-Tanner diffusion weighted images is hampered by the geometric distortions that result from the large residual 3-D eddy current field induced. In this work, we aimed to predict, using linear response theory, the residual 3-D eddy current field required for geometric distortion correction based on phantom eddy current field measurements. The predicted 3-D eddy current field induced by the diffusion-weighting gradients was able to reduce the root mean square error of the residual eddy current field to ~1 Hz. The model's performance was tested on diffusion weighted images of four normal volunteers, following distortion correction, the quality of the Stejskal-Tanner diffusion-weighted images was found to have comparable quality to image registration based corrections (FSL) at low b-values. Unlike registration techniques the correction was not hindered by low SNR at high b-values, and results in improved image quality relative to FSL. Characterization of the 3-D eddy current field with linear response theory enables the prediction of the 3-D eddy current field required to correct eddy current induced geometric distortions for a wide range of clinical and high b-value protocols.

  10. Use of 3-D magnetic resonance electrical impedance tomography in detecting human cerebral stroke: a simulation study*

    PubMed Central

    Gao, Nuo; Zhu, Shan-an; He, Bin

    2005-01-01

    We have developed a new three dimensional (3-D) conductivity imaging approach and have used it to detect human brain conductivity changes corresponding to acute cerebral stroke. The proposed Magnetic Resonance Electrical Impedance Tomography (MREIT) approach is based on the J-Substitution algorithm and is expanded to imaging 3-D subject conductivity distribution changes. Computer simulation studies have been conducted to evaluate the present MREIT imaging approach. Simulations of both types of cerebral stroke, hemorrhagic stroke and ischemic stroke, were performed on a four-sphere head model. Simulation results showed that the correlation coefficient (CC) and relative error (RE) between target and estimated conductivity distributions were 0.9245±0.0068 and 8.9997%±0.0084%, for hemorrhagic stroke, and 0.6748±0.0197 and 8.8986%±0.0089%, for ischemic stroke, when the SNR (signal-to-noise radio) of added GWN (Gaussian White Noise) was 40. The convergence characteristic was also evaluated according to the changes of CC and RE with different iteration numbers. The CC increases and RE decreases monotonously with the increasing number of iterations. The present simulation results show the feasibility of the proposed 3-D MREIT approach in hemorrhagic and ischemic stroke detection and suggest that the method may become a useful alternative in clinical diagnosis of acute cerebral stroke in humans. PMID:15822161

  11. Perineal body anatomy in living women: 3-D analysis using thin-slice magnetic resonance imaging

    PubMed Central

    Larson, Kindra A.; Yousuf, Aisha; Lewicky-Gaupp, Christina; Fenner, Dee E.; DeLancey, John O.L.

    2012-01-01

    Objective To describe a framework for visualizing the perineal body's complex anatomy using thin-slice MR imaging. Study Design Two mm-thick MR images were acquired in 11 women with normal pelvic support and no incontinence/prolapse symptoms. Anatomic structures were analyzed in axial, sagittal and coronal slices. 3-D models were generated from these images. Results Three distinct perineal body regions are visible on MRI: (1) a superficial region at the level of the vestibular bulb, (2) a mid region at the proximal end of the superficial transverse perineal muscle, and (3) a deep region at the level of the midurethra and puborectalis muscle. Structures are best visualized on axial scans while cranio-caudal relationships are appreciated on sagittal scans. The 3-D model further clarifies inter-relationships. Conclusion Advances in MR technology allow visualization of perineal body anatomy in living women and development of 3D models which enhance our understanding of its three different regions: superficial, mid and deep. PMID:21055513

  12. 3D magnetic resonance imaging as a non-invasive tool for investigating water-filled karst formations

    NASA Astrophysics Data System (ADS)

    Legchenko, A.; Ezersky, M.; Boucher, M.; Chevalier, A.; Vouillamoz, J.-M.

    2012-04-01

    Magnetic Resonance Sounding (MRS) is a geophysical technique developed for groundwater exploration. MRS can be used for reliable identification of karst aquifers because of the relaxation time of the magnetic resonance signal (T1) is longer for bulk water in karst caverns and channels (about 2 s) than for water in porous rock (few tens of ms). MRS is sensitive primary to groundwater volume but electrically conductive layers modify electromagnetic fields in the subsurface and thus may have an effect on MRS performance. Generally, the study of a karst requires a 3D field set-up and we developed a measuring procedure and interpretation software that makes it possible to image heterogeneous water-bearing geological formations down to about 80 m (3D-SNMR method). Numerical modeling results show that limited resolution of the method allows only identification of large karst formations. For example detectable karst should be larger than a few hundred cubic meters when karst is located close to the surface and a few thousand cubic meters when it is located at 60 m. Time Domain Electromagnetic method (TDEM) is known as an efficient tool for investigating electrical conductivity of rocks. TDEM results allow more accurate computing of the EM field in the subsurface and thus contribute for improving accuracy of MRS results. TDEM and 3D-SNMR methods were applied jointly in the Dead Sea coast of Israel (Nahal Hever South). The subsurface in this area is heterogeneous and composed of intercalated sand and clay layers over a salt rock, which is partly karstified. Groundwater is very saline, with a chloride concentration of 100-225 g/l thus rendering the resistivity of geological formations less than 1 ohm-m. We have shown numerically that under Dead Sea coast conditions, 3D-SNMR is able to detect and to locate the target within an error of a few tens of meters. In the investigated area (500×500 m2) our results reveal a very heterogeneous shallow aquifer that could be divided into

  13. Kidney stone imaging with 3D ultra-short echo time (UTE) magnetic resonance imaging. A phantom study.

    PubMed

    Ibrahim, El-Sayed H; Pooley, Robert A; Bridges, Mellena D; Cernigliaro, Joseph G; Haley, William E

    2014-01-01

    Computed tomography (CT) is the current gold standard for imaging kidney stones, albeit at the cost of radiation exposure. Conventional magnetic resonance imaging (MRI) sequences are insensitive to detecting the stones because of their appearance as a signal void. With the development of 2D ultra-short echo-time (UTE) MRI sequences, it becomes possible to image kidney stones in vitro. In this work, we optimize and implement a modified 3D UTE MRI sequence for imaging kidney stones embedded in agarose phantoms mimicking the kidney tissue and in urine phantoms at 3.0T. The proposed technique is capable of imaging the stones with high spatial resolution in a short scan time.

  14. [Measurement of left atrial and ventricular volumes in real-time 3D echocardiography. Validation by nuclear magnetic resonance

    NASA Technical Reports Server (NTRS)

    Bauer, F.; Shiota, T.; Qin, J. X.; White, R. D.; Thomas, J. D.

    2001-01-01

    The measurement of the left ventricular ejection fraction is important for the evaluation of cardiomyopathy and depends on the measurement of left ventricular volumes. There are no existing conventional echocardiographic means of measuring the true left atrial and ventricular volumes without mathematical approximations. The aim of this study was to test anew real time 3-dimensional echocardiographic system of calculating left atrial and ventricular volumes in 40 patients after in vitro validation. The volumes of the left atrium and ventricle acquired from real time 3-D echocardiography in the apical view, were calculated in 7 sections parallel to the surface of the probe and compared with atrial (10 patients) and ventricular (30 patients) volumes calculated by nuclear magnetic resonance with the simpson method and with volumes of water in balloons placed in a cistern. Linear regression analysis showed an excellent correlation between the real volume of water in the balloons and volumes given in real time 3-dimensional echocardiography (y = 0.94x + 5.5, r = 0.99, p < 0.001, D = -10 +/- 4.5 ml). A good correlation was observed between real time 3-dimensional echocardiography and nuclear magnetic resonance for the measurement of left atrial and ventricular volumes (y = 0.95x - 10, r = 0.91, p < 0.001, D = -14.8 +/- 19.5 ml and y = 0.87x + 10, r = 0.98, P < 0.001, D = -8.3 +/- 18.7 ml, respectively. The authors conclude that real time three-dimensional echocardiography allows accurate measurement of left heart volumes underlying the clinical potential of this new 3-D method.

  15. 3D cine magnetic resonance imaging of rat lung ARDS using gradient-modulated SWIFT with retrospective respiratory gating

    NASA Astrophysics Data System (ADS)

    Kobayashi, Naoharu; Lei, Jianxun; Utecht, Lynn; Garwood, Michael; Ingbar, David H.; Bhargava, Maneesh

    2015-03-01

    SWeep Imaging with Fourier Transformation (SWIFT) with gradient modulation and DC navigator retrospective gating is introduced as a 3D cine magnetic resonance imaging (MRI) method for the lung. In anesthetized normal rats, the quasi-simultaneous excitation and acquisition in SWIFT enabled extremely high sensitivity to the fast-decaying parenchymal signals (TE=~4 μs), which are invisible with conventional MRI techniques. Respiratory motion information was extracted from DC navigator signals and the SWIFT data were reconstructed to 3D cine images with 16 respiratory phases. To test this technique's capabilities, rats exposed to > 95% O2 for 60 hours for induction of acute respiratory distress syndrome (ARDS), were imaged and compared with normal rat lungs (N=7 and 5 for ARDS and normal groups, respectively). SWIFT images showed lung tissue density differences along the gravity direction. In the cine SWIFT images, a parenchymal signal drop at the inhalation phase was consistently observed for both normal and ARDS rats due to lung inflation (i.e. decrease of the proton density), but the drop was less for ARDS rats. Depending on the respiratory phase and lung region, the lungs from the ARDS rats showed 1-24% higher parenchymal signal intensities relative to the normal rat lungs, likely due to accumulated extravascular water (EVLW). Those results demonstrate that SWIFT has high enough sensitivity for detecting the lung proton density changes due to gravity, different phases of respiration and accumulation of EVLW in the rat ARDS lungs.

  16. 3D Cine Magnetic Resonance Imaging of Rat Lung ARDS using Gradient-modulated SWIFT with Retrospective Respiratory Gating.

    PubMed

    Kobayashi, Naoharu; Lei, Jianxun; Utecht, Lynn; Garwood, Michael; Ingbar, David; Bhargava, Maneesh

    2015-02-21

    SWeep Imaging with Fourier Transformation (SWIFT) with gradient modulation and DC navigator retrospective gating is introduced as a 3D cine magnetic resonance imaging (MRI) method for the lung. The quasi-simultaneous excitation and acquisition in SWIFT enabled extremely high sensitivity to the fast-decaying parenchymal signals (TE=~4 μs), which are invisible with conventional MRI techniques. Based on respiratory motion information extracted from DC navigator signals, the SWIFT data were reconstructed to 3D cine images with 16 respiratory phases. To test the capability of the proposed technique, rats exposed to > 95% O2 for 60 hours for induction of acute respiratory distress syndrome (ARDS), were imaged and compared with normal rat lungs (N=7 and 5 for ARDS and normal group, respectively). SWIFT images showed lung tissue density difference along the gravity direction. In the cine SWIFT images, parenchymal signal drop at the inhalation phase was consistently observed for both normal and ARDS rats due to inflation of the lung (i.e. decrease of the proton density), but the drop was less for ARDS rats. Depending on the respiration phase and lung region, the lungs from the ARDS rats showed 1-24% higher parenchymal signal intensities relative to the normal rat lungs, which would be mainly from accumulation of extravascular water (EVLW). Those results demonstrate that SWIFT has high enough sensitivity for detecting the lung proton density changes due to gravity, different respiration phases and accumulation of EVLW in the rat ARDS lungs.

  17. Novel methodology for 3D reconstruction of carotid arteries and plaque characterization based upon magnetic resonance imaging carotid angiography data.

    PubMed

    Sakellarios, Antonis I; Stefanou, Kostas; Siogkas, Panagiotis; Tsakanikas, Vasilis D; Bourantas, Christos V; Athanasiou, Lambros; Exarchos, Themis P; Fotiou, Evangelos; Naka, Katerina K; Papafaklis, Michail I; Patterson, Andrew J; Young, Victoria E L; Gillard, Jonathan H; Michalis, Lampros K; Fotiadis, Dimitrios I

    2012-10-01

    In this study, we present a novel methodology that allows reliable segmentation of the magnetic resonance images (MRIs) for accurate fully automated three-dimensional (3D) reconstruction of the carotid arteries and semiautomated characterization of plaque type. Our approach uses active contours to detect the luminal borders in the time-of-flight images and the outer vessel wall borders in the T(1)-weighted images. The methodology incorporates the connecting components theory for the automated identification of the bifurcation region and a knowledge-based algorithm for the accurate characterization of the plaque components. The proposed segmentation method was validated in randomly selected MRI frames analyzed offline by two expert observers. The interobserver variability of the method for the lumen and outer vessel wall was -1.60%±6.70% and 0.56%±6.28%, respectively, while the Williams Index for all metrics was close to unity. The methodology implemented to identify the composition of the plaque was also validated in 591 images acquired from 24 patients. The obtained Cohen's k was 0.68 (0.60-0.76) for lipid plaques, while the time needed to process an MRI sequence for 3D reconstruction was only 30 s. The obtained results indicate that the proposed methodology allows reliable and automated detection of the luminal and vessel wall borders and fast and accurate characterization of plaque type in carotid MRI sequences. These features render the currently presented methodology a useful tool in the clinical and research arena.

  18. The feasibility assessment of radiation dose of movement 3D NIPAM gel by magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Hsieh, Chih-Ming; Leung, Joseph Hang; Ng, Yu-Bun; Cheng, Chih-Wu; Sun, Jung-Chang; Lin, Ping-Chin; Hsieh, Bor-Tsung

    2015-11-01

    NIPAM dosimeter is widely accepted and recommended for its 3D distribution and accuracy in dose absorption. Up to the moment, most research works on dose measurement are based on a fixed irradiation target without the consideration of the effect from physiological motion. We present a study to construct a respiratory motion simulating patient anatomical and dosimetry model for the study of dosimetic effect of organ motion. The dose on fixed and motion targets was measured by MRI after a dose adminstration of 1, 2, 5, 8, and 10 Gy from linear accelerator. Comparison of two situations is made. The average sensitivity of fixed NIPAM was 0.1356 s-1/Gy with linearity R2=0.998. The average sensitivity of movement NIPAM was 0.1366 s-1/Gy with linearity R2=0.998 both having only 0.001 of the sensitivity difference. The difference between the two based on dose rate dependency, position and depth was not significant. There was thus no apparent impact on NIPAM dosimeter from physiological motion. The high sensitivity, linearity and stability of NIPAM dosimeter proved to be an ideal apparatus in the dose measurement in these circumstances.

  19. Interactive 3D segmentation of the prostate in magnetic resonance images using shape and local appearance similarity analysis

    NASA Astrophysics Data System (ADS)

    Shahedi, Maysam; Fenster, Aaron; Cool, Derek W.; Romagnoli, Cesare; Ward, Aaron D.

    2013-03-01

    3D segmentation of the prostate in medical images is useful to prostate cancer diagnosis and therapy guidance, but is time-consuming to perform manually. Clinical translation of computer-assisted segmentation algorithms for this purpose requires a comprehensive and complementary set of evaluation metrics that are informative to the clinical end user. We have developed an interactive 3D prostate segmentation method for 1.5T and 3.0T T2-weighted magnetic resonance imaging (T2W MRI) acquired using an endorectal coil. We evaluated our method against manual segmentations of 36 3D images using complementary boundary-based (mean absolute distance; MAD), regional overlap (Dice similarity coefficient; DSC) and volume difference (ΔV) metrics. Our technique is based on inter-subject prostate shape and local boundary appearance similarity. In the training phase, we calculated a point distribution model (PDM) and a set of local mean intensity patches centered on the prostate border to capture shape and appearance variability. To segment an unseen image, we defined a set of rays - one corresponding to each of the mean intensity patches computed in training - emanating from the prostate centre. We used a radial-based search strategy and translated each mean intensity patch along its corresponding ray, selecting as a candidate the boundary point with the highest normalized cross correlation along each ray. These boundary points were then regularized using the PDM. For the whole gland, we measured a mean+/-std MAD of 2.5+/-0.7 mm, DSC of 80+/-4%, and ΔV of 1.1+/-8.8 cc. We also provided an anatomic breakdown of these metrics within the prostatic base, mid-gland, and apex.

  20. Investigating Cardiac Motion Patterns Using Synthetic High-Resolution 3D Cardiovascular Magnetic Resonance Images and Statistical Shape Analysis

    PubMed Central

    Biffi, Benedetta; Bruse, Jan L.; Zuluaga, Maria A.; Ntsinjana, Hopewell N.; Taylor, Andrew M.; Schievano, Silvia

    2017-01-01

    Diagnosis of ventricular dysfunction in congenital heart disease is more and more based on medical imaging, which allows investigation of abnormal cardiac morphology and correlated abnormal function. Although analysis of 2D images represents the clinical standard, novel tools performing automatic processing of 3D images are becoming available, providing more detailed and comprehensive information than simple 2D morphometry. Among these, statistical shape analysis (SSA) allows a consistent and quantitative description of a population of complex shapes, as a way to detect novel biomarkers, ultimately improving diagnosis and pathology understanding. The aim of this study is to describe the implementation of a SSA method for the investigation of 3D left ventricular shape and motion patterns and to test it on a small sample of 4 congenital repaired aortic stenosis patients and 4 age-matched healthy volunteers to demonstrate its potential. The advantage of this method is the capability of analyzing subject-specific motion patterns separately from the individual morphology, visually and quantitatively, as a way to identify functional abnormalities related to both dynamics and shape. Specifically, we combined 3D, high-resolution whole heart data with 2D, temporal information provided by cine cardiovascular magnetic resonance images, and we used an SSA approach to analyze 3D motion per se. Preliminary results of this pilot study showed that using this method, some differences in end-diastolic and end-systolic ventricular shapes could be captured, but it was not possible to clearly separate the two cohorts based on shape information alone. However, further analyses on ventricular motion allowed to qualitatively identify differences between the two populations. Moreover, by describing shape and motion with a small number of principal components, this method offers a fully automated process to obtain visually intuitive and numerical information on cardiac shape and motion

  1. Investigation of surfactant-enhanced mass removal and flux reduction in 3D correlated permeability fields using magnetic resonance imaging.

    PubMed

    Zhang, Changyong; Werth, Charles J; Webb, Andrew G

    2008-09-10

    Magnetic resonance imaging (MRI) was used to visualize the NAPL source zone architecture before and after surfactant-enhanced NAPL dissolution in three-dimensional (3D) heterogeneously packed flowcells characterized by different longitudinal correlation lengths: 2.1 cm (aquifer 1) and 1.1 cm (aquifer 2). Surfactant flowpaths were determined by imaging the breakthrough of a paramagnetic tracer (MnCl(2)) analyzed by the method of moments. In both experimental aquifers, preferential flow occurred in high permeability materials with low NAPL saturations, and NAPL was preferentially removed from the top of the aquifers with low saturation. Alternate flushing with water and two surfactant pulses (5-6 pore volumes each) resulted in approximately 63% of NAPL mass removal from both aquifers. However, overall reduction in mass flux (Mass Flux 1) exiting the flowcell was lower in aquifer 2 (68%) than in aquifer 1 (81%), and local effluent concentrations were found to increase by as high as 120 times at local sampling ports from aquifer 2 after surfactant flushing. 3D MRI images of NAPL revealed that NAPL migrated downward and created additional NAPL source zones in previously uncontaminated areas at the bottom of the aquifers. The additional NAPL source zones were created in the direction transverse to flow in aquifer 2, which explains the higher mass flux relative to aquifer 1. Analysis using a total trapping number indicates that mobilization of NAPL trapped in the two coarsest sand fractions is possible when saturation is below 0.5 and 0.4, respectively. Results from this study highlight the potential impacts of porous media heterogeneity and NAPL source zone architecture on advanced in-situ flushing technologies.

  2. MO-F-CAMPUS-I-04: Magnetic Resonance Imaging of An in Vitro 3D Tumor Model

    SciTech Connect

    Veiga, C; Long, T; Siow, B; Loizidou, M; Royle, G; Ricketts, K

    2015-06-15

    Purpose: To investigate the use of an in vitro 3D tumor model (tumoroid) as a bio-phantom for repetitive and sequential magnetic resonance imaging (MRI) studies. Methods: The tissue engineered tumoroid comprised an artificial cancer mass (ACM) containing 30 million HT29 cancer cells seeded in a collagen type I matrix, whose density was increased by plastic compression (dry/wet weight=40%). The ACM was embedded in an uncompressed collagen gel that mimicked the tumor stroma, and the tumoroid was incubated for 24h before imaging. Images were acquired using the 1T ICON™ (Bruker Corporation, Billerica, MA) MRI scanner. T1 maps were calculated using an IR-RARE sequence (TE=12ms, TR=10000ms, 7 inversion times), while for T2 maps a MSME technique (TR=6000ms, 16 echoes) was used. T1 and T2 fittings were performed using a pixel-wise approach to produce relaxometric parametric maps. Results: The images acquired and corresponding T1 and T2 maps indicate contrast between the ACM and the stroma. T1 was 2500 and 2800ms, while T2 was 520 and 760ms, for the ACM and stroma respectively. The ACM construct was not homogenous and internal features were visible, which can be explained by local gradients of cell and/or collagen density. The viability of the cells was confirmed via confocal microscopy for several days after the imaging session, demonstrating the suitability of the tumoroid for sequential imaging studies. Conclusions: We have engineered a tumor model compatible with repetitive and sequential MRI. We found T1 and T2 contrast between the ACM and stroma using a pre-clinical MRI scanner. The model, which enables controllable cell and matrix densities, has potential for a wide range of applications in radiotherapy, such as to study tumor progression and to validate imaging biomarkers. Further work is necessary to understand the mechanisms behind the contrast achieved, and to correlate findings with biology and histology data.

  3. Cross-Modality Validation of Acetabular Surface Models Using 3-D Ultrasound Versus Magnetic Resonance Imaging in Normal and Dysplastic Infant Hips.

    PubMed

    Diederichs, Chad; Heath, Alana; Hareendranathan, Abhilash R; Zonoobi, Dornoosh; Kuntze, Gregor; Dulai, Sukhdeep; Mabee, Myles G; Ronsky, Janet L; Jaremko, Jacob L

    2016-09-01

    Current imaging diagnosis of developmental dysplasia of the hip (DDH) in infancy relies on 2-D ultrasound (US), which is highly operator-dependent. 3-D US offers more complete, and potentially more reliable, imaging of infant hip geometry. We sought to validate the fidelity of acetabular surface models obtained by 3-D US against those obtained concurrently by magnetic resonance imaging (MRI). 3-D US and MRI scans were performed on the same d in 20 infants with normal to severely dysplastic hips (mean age, 57 d; range 13-181 d). 3-D US was performed by two observers using a Philips VL13-5 probe. Coronal 3-D multi-echo data image combination (MEDIC) magnetic resonance (MR) images (1-mm slice thickness) were obtained, usually without sedation, in a 1.5 T Siemens unit. Acetabular surface models were generated for 40 hips from 3-D US and MRI using semi-automated tracing software, separately by three observers. For each hip, the 3-D US and MRI models were co-registered to overlap as closely as possible using Amira software, and the root mean square (RMS) distances between points on the models were computed. 3-D US scans took 3.2 s each. Inter-modality variability was visually minimal. Mean RMS distance between corresponding points on the acetabular surface at 3-D US and MRI was 0.4 ± 0.3 mm, with 95% confidence interval <1 mm. Mean RMS errors for inter-observer and intra-observer comparisons were significantly less for 3-D US than for MRI, while inter-scan and inter-modality comparisons showed no significant difference. Acetabular geometry was reproduced by 3-D US surface models within 1 mm of the corresponding 3-D MRI surface model, and the 3-D US models were more reliable. This validates the fidelity of 3-D US modeling and encourages future use of 3-D US in assessing infant acetabulum anatomy, which may be useful to detect and monitor treatment of hip dysplasia.

  4. A novel skeleton based quantification and 3-D volumetric visualization of left atrium fibrosis using late gadolinium enhancement magnetic resonance imaging.

    PubMed

    Ravanelli, Daniele; dal Piaz, Elena Costanza; Centonze, Maurizio; Casagranda, Giulia; Marini, Massimiliano; Del Greco, Maurizio; Karim, Rashed; Rhode, Kawal; Valentini, Aldo

    2014-02-01

    This work presents the results of a new tool for 3-D segmentation, quantification and visualization of cardiac left atrium fibrosis, based on late gadolinium enhancement magnetic resonance imaging (LGE-MRI), for stratifying patients with atrial fibrillation (AF) that are candidates for radio-frequency catheter ablation. In this study 10 consecutive patients suffering AF with different grades of atrial fibrosis were considered. LGE-MRI and magnetic resonance angiography (MRA) images were used to detect and quantify fibrosis of the left atrium using a threshold and 2-D skeleton based approach. Quantification and 3-D volumetric views of atrial fibrosis were compared with quantification and 3-D bipolar voltage maps measured with an electro-anatomical mapping (EAM) system, the clinical reference standard technique for atrial substrate characterization. Segmentation and quantification of fibrosis areas proved to be clinically reliable among all different fibrosis stages. The proposed tool obtains discrepancies in fibrosis quantification less than 4% from EAM results and yields accurate 3-D volumetric views of fibrosis of left atrium. The novel 3-D visualization and quantification tool based on LGE-MRI allows detection of cardiac left atrium fibrosis areas. This noninvasive method provides a clinical alternative to EAM systems for quantification and localization of atrial fibrosis.

  5. Automatic quantification of aortic regurgitation using 3D full volume color doppler echocardiography: a validation study with cardiac magnetic resonance imaging.

    PubMed

    Choi, Jaehuk; Hong, Geu-Ru; Kim, Minji; Cho, In Jeong; Shim, Chi Young; Chang, Hyuk-Jae; Mancina, Joel; Ha, Jong-Won; Chung, Namsik

    2015-10-01

    Recent advances in real-time three-dimensional (3D) echocardiography provide the automated measurement of mitral inflow and aortic stroke volume without the need to assume the geometry of the heart. The aim of this study is to explore the ability of 3D full volume color Doppler echocardiography (FVCDE) to quantify aortic regurgitation (AR). Thirty-two patients with more than a moderate degree of AR were enrolled. AR volume was measured by (1) two-dimensional-CDE, using the proximal isovelocity surface area (PISA) and (2) real-time 3D-FVCDE with (3) phase-contrast cardiac magnetic resonance imaging (PC-CMR) as the reference method. Automated AR quantification using 3D-FVCDE was feasible in 30 of the 32 patients. 2D-PISA underestimated the AR volume compared to 3D-FVCDE and PC-CMR (38.6 ± 9.9 mL by 2D-PISA; 49.5 ± 10.2 mL by 3D-FVCDE; 52.3 ± 12.6 mL by PC-CMR). The AR volume assessed by 3D-FVCDE showed better correlation and agreement with PC-CMR (r = 0.93, p < 0.001, 2SD: 9.5 mL) than did 2D-PISA (r = 0.76, p < 0.001, 2SD: 15.7 mL). When used to classify AR severity, 3D-FVCDE agreed better with PC-CMR (k = 0.94) than did 2D-PISA (k = 0.53). In patients with eccentric jets, only 30% were correctly graded by 2D-PISA. Conversely, almost all patients with eccentric jets (86.7%) were correctly graded by 3D-FVCDE. In patients with multiple jets, only 3 out of 10 were correctly graded by 2D-PISA, while 3D-FVCDE correctly graded 9 out of 10 of these patients. Automated quantification of AR using the 3D-FVCDE method is clinically feasible and more accurate than the current 2D-based method. AR quantification by 2D-PISA significantly misclassified AR grade in patients with eccentric or multiple jets. This study demonstrates that 3D-FVCDE is a valuable tool to accurately measure AR volume regardless of AR characteristics.

  6. In vivo application of 3D-line skeleton graph analysis (LSGA) technique with high-resolution magnetic resonance imaging of trabecular bone structure.

    PubMed

    Pothuaud, Laurent; Newitt, David C; Lu, Ying; MacDonald, Brian; Majumdar, Sharmila

    2004-05-01

    Over the last several years magnetic resonance (MR) imaging has emerged as a means of measuring in vivo 3D trabecular bone structure. In particular, MR based diagnosis could be used to complement standard bone mineral density (BMD) methods for assessing osteoporosis and evaluating longitudinal changes. The aim of this study was to demonstrate the feasibility of using the 3D-LSGA technique for the evaluation of trabecular bone structure of high-resolution MR images, particularly for assessing longitudinal changes, in vivo. First, the reproducibility of topological 3D-LSGA based measurements was evaluated in a set of seven volunteers, and coefficients of variations ranged from 3.5% to 6%. Second, high-resolution MR images of the radius in 30 postmenopausal women from a placebo controlled drug study (Idoxifene), divided into placebo ( n=9) and treated ( n=21) groups, were obtained at baseline (BL) and after 1 year of treatment (follow-up, FU). In addition, dual X-ray absorptiometry (DXA) measures of BMD were obtained in the distal radius. Standard morphological measurements based on the mean intercept length (MIL) technique as well as 3D-LSGA based measurements were applied to the 3D MR images. Significant changes from BL to FU were detected, in the treated group, using the topological 3D-LSGA based measurements, morphological measures of volume of connected trabeculae and App Tb.N from MIL analysis. The duration of the study was short, and the number of patients remaining in the study was small, hence these results cannot be interpreted with regard to a true therapeutic response. Furthermore, the site (wrist) and the drug (idoxifene) are not optimal for follow-up study. However, this paper demonstrated the feasibility of using 3D-LSGA based evaluation coupled with in vivo high-resolution MR imaging as a complementary approach for the monitoring of trabecular bone changes in individual subjects.

  7. Characteristics of spondylotic myelopathy on 3D driven-equilibrium fast spin echo and 2D fast spin echo magnetic resonance imaging: a retrospective cross-sectional study.

    PubMed

    Abdulhadi, Mike A; Perno, Joseph R; Melhem, Elias R; Nucifora, Paolo G P

    2014-01-01

    In patients with spinal stenosis, magnetic resonance imaging of the cervical spine can be improved by using 3D driven-equilibrium fast spin echo sequences to provide a high-resolution assessment of osseous and ligamentous structures. However, it is not yet clear whether 3D driven-equilibrium fast spin echo sequences adequately evaluate the spinal cord itself. As a result, they are generally supplemented by additional 2D fast spin echo sequences, adding time to the examination and potential discomfort to the patient. Here we investigate the hypothesis that in patients with spinal stenosis and spondylotic myelopathy, 3D driven-equilibrium fast spin echo sequences can characterize cord lesions equally well as 2D fast spin echo sequences. We performed a retrospective analysis of 30 adult patients with spondylotic myelopathy who had been examined with both 3D driven-equilibrium fast spin echo sequences and 2D fast spin echo sequences at the same scanning session. The two sequences were inspected separately for each patient, and visible cord lesions were manually traced. We found no significant differences between 3D driven-equilibrium fast spin echo and 2D fast spin echo sequences in the mean number, mean area, or mean transverse dimensions of spondylotic cord lesions. Nevertheless, the mean contrast-to-noise ratio of cord lesions was decreased on 3D driven-equilibrium fast spin echo sequences compared to 2D fast spin echo sequences. These findings suggest that 3D driven-equilibrium fast spin echo sequences do not need supplemental 2D fast spin echo sequences for the diagnosis of spondylotic myelopathy, but they may be less well suited for quantitative signal measurements in the spinal cord.

  8. 3D segmentation and quantification of magnetic resonance data: application to the osteonecrosis of the femoral head

    NASA Astrophysics Data System (ADS)

    Klifa, Catherine S.; Lynch, John A.; Zaim, Souhil; Genant, Harry K.

    1999-05-01

    The general objective of our study is the development of a clinically robust three-dimensional segmentation and quantification technique of Magnetic Resonance (MR) data, for the objective and quantitative evaluation of the osteonecrosis (ON) of the femoral head. This method will help evaluate the effects of joint preserving treatments for femoral head osteonecrosis from MR data. The disease is characterized by tissue changes (death of bone and marrow cells) within the weight-bearing portion of the femoral head. Due to the fuzzy appearance of lesion tissues and their different intensity patterns in various MR sequences, we proposed a semi-automatic multispectral segmentation of MR data introducing data constraints (anatomical and geometrical) and using a classical K-means unsupervised clustering algorithm. The method was applied on ON patient data. Results of volumetric measurements and configuration of various tissues obtained with the semi- automatic method were compared with quantitative results delineated by a trained radiologist.

  9. Antenatal Diagnosis of a Large Immature Abdominal Wall Teratoma by 2D-3D Ultrasound Using HDlive and Magnetic Resonance Imaging.

    PubMed

    Werner, Heron; Mocarzel, Carolina; Sá, Renato Augusto; Tonni, Gabriele; Novoa Y Novoa, Victoria Arruga; Avvad-Portari, Elyzabeth; Bonasoni, Paola; Araujo Júnior, Edward

    2016-01-01

    We describe the first case of prenatally detected teratoma of the fetal abdomen wall using ultrasound and fetal magnetic resonance imaging (MRI). A heterogeneous mass, partly solid and cystic, originating from the anterior abdominal wall of the fetus close to an omphalocele sac was detected by means of 2D/3D ultrasound and MRI. Amniodrainage was performed and due to sign of impending fetal risk, an emergency Cesarean section was performed. A bulky, crumbly and bleeding tumoral mass was confirmed at delivery. Ligation of the supplying artery to the tumor was complicated by uncontrollable hemorrhage and early neonatal death. Pathology identified the tumor as an immature teratoma of the anterior fetal abdominal wall. 2D/3D ultrasound, especially using HDlive application and MRI demonstrated accurate detection and characterization of this congenital tumor.

  10. Multifractal analysis of white matter structural changes on 3D magnetic resonance imaging between normal aging and early Alzheimer’s disease

    NASA Astrophysics Data System (ADS)

    Ni, Huang-Jing; Zhou, Lu-Ping; Zeng, Peng; Huang, Xiao-Lin; Liu, Hong-Xing; Ning, Xin-Bao

    2015-07-01

    Applications of multifractal analysis to white matter structure changes on magnetic resonance imaging (MRI) have recently received increasing attentions. Although some progresses have been made, there is no evident study on applying multifractal analysis to evaluate the white matter structural changes on MRI for Alzheimer’s disease (AD) research. In this paper, to explore multifractal analysis of white matter structural changes on 3D MRI volumes between normal aging and early AD, we not only extend the traditional box-counting multifractal analysis (BCMA) into the 3D case, but also propose a modified integer ratio based BCMA (IRBCMA) algorithm to compensate for the rigid division rule in BCMA. We verify multifractal characteristics in 3D white matter MRI volumes. In addition to the previously well studied multifractal feature, Δα, we also demonstrated Δf as an alternative and effective multifractal feature to distinguish NC from AD subjects. Both Δα and Δf are found to have strong positive correlation with the clinical MMSE scores with statistical significance. Moreover, the proposed IRBCMA can be an alternative and more accurate algorithm for 3D volume analysis. Our findings highlight the potential usefulness of multifractal analysis, which may contribute to clarify some aspects of the etiology of AD through detection of structural changes in white matter. Project supported by the National Natural Science Foundation of China (Grant No. 61271079), the Vice Chancellor Research Grant in University of Wollongong, and the Priority Academic Program Development of Jiangsu Higher Education Institutions, China.

  11. Alpha shape theory for 3D visualization and volumetric measurement of brain tumor progression using magnetic resonance images.

    PubMed

    Hamoud Al-Tamimi, Mohammed Sabbih; Sulong, Ghazali; Shuaib, Ibrahim Lutfi

    2015-07-01

    Resection of brain tumors is a tricky task in surgery due to its direct influence on the patients' survival rate. Determining the tumor resection extent for its complete information via-à-vis volume and dimensions in pre- and post-operative Magnetic Resonance Images (MRI) requires accurate estimation and comparison. The active contour segmentation technique is used to segment brain tumors on pre-operative MR images using self-developed software. Tumor volume is acquired from its contours via alpha shape theory. The graphical user interface is developed for rendering, visualizing and estimating the volume of a brain tumor. Internet Brain Segmentation Repository dataset (IBSR) is employed to analyze and determine the repeatability and reproducibility of tumor volume. Accuracy of the method is validated by comparing the estimated volume using the proposed method with that of gold-standard. Segmentation by active contour technique is found to be capable of detecting the brain tumor boundaries. Furthermore, the volume description and visualization enable an interactive examination of tumor tissue and its surrounding. Admirable features of our results demonstrate that alpha shape theory in comparison to other existing standard methods is superior for precise volumetric measurement of tumor.

  12. The Relationship of 3D Human Skull Motion to Brain Tissue Deformation in Magnetic Resonance Elastography Studies.

    PubMed

    Badachhape, Andrew A; Okamoto, Ruth J; Durham, Ramona S; Efron, Brent D; Nadell, Sam J; Johnson, Curtis L; Bayly, Philip V

    2017-03-07

    In traumatic brain injury (TBI), membranes such as the dura mater, arachnoid mater, and pia mater play a vital role in transmitting motion from the skull to brain tissue. Magnetic Resonance Elastography (MRE) is an imaging technique developed for non-invasive estimation of soft tissue material parameters. In MRE, dynamic deformation of brain tissue is induced by skull vibrations; however skull motion and its mode of transmission to the brain remain largely uncharacterized. In this study, displacements of points in the skull, reconstructed using data from an array of MRI-safe accelerometers, were compared to displacements of neighboring material points in brain tissue, estimated from MRE measurements. Comparison of the relative amplitudes, directions, and temporal phases of harmonic motion in the skulls and brains of six human subjects shows that the skull-brain interface significantly attenuates and delays transmission of motion from skull to brain. In contrast, in a cylindrical gelatin "phantom", displacements of the rigid case (reconstructed from accelerometer data) were transmitted to the gelatin inside (estimated from MRE data) with little attenuation or phase lag. This quantitative characterization of the skull-brain interface will be valuable in the parameterization and validation of computer models of TBI.

  13. Developing a Magnetic Resonance Imaging measurement of the forces within 3D granular materials under external loads

    NASA Astrophysics Data System (ADS)

    Elrington, Stefan; Bertrand, Thibault; Frey, Merideth; Shattuck, Mark; O'Hern, Corey; Barrett, Sean

    2014-03-01

    Granular materials are comprised of an ensemble of discrete macroscopic grains that interact with each other via highly dissipative forces. These materials are ubiquitous in our everyday life ranging in scale from the granular media that forms the Earth's crust to that used in agricultural and pharmaceutical industries. Granular materials exhibit complex behaviors that are poorly understood and cannot be easily described by statistical mechanics. Under external loads individual grains are jammed into place by a network of force chains. These networks have been imaged in quasi two-dimensional and on the outer surface of three-dimensional granular materials. Our goal is to use magnetic resonance imaging (MRI) to detect contact forces deep within three-dimensional granular materials, using hydrogen-1 relaxation times as a reporter for changes in local stress and strain. To this end, we use a novel pulse sequence to narrow the line width of hydrogen-1 in rubber. Here we present our progress to date, and prospects for future improvements.

  14. Protocol for volumetric segmentation of medial temporal structures using high-resolution 3-D magnetic resonance imaging.

    PubMed

    Bonilha, Leonardo; Kobayashi, Eliane; Cendes, Fernando; Min Li, Li

    2004-06-01

    Quantitative analysis of brain structures in normal subjects and in different neurological conditions can be carried out in vivo through magnetic resonance imaging (MRI) volumetric studies. The use of high-resolution MRI combined with image post-processing that allows simultaneous multiplanar view may facilitate volumetric segmentation of temporal lobe structures. We define a protocol for volumetric studies of medial temporal lobe structures using high-resolution MR images and we studied 30 healthy subjects (19 women; mean age, 33 years; age range, 21-55 years). Images underwent field non-homogeneity correction and linear stereotaxic transformation into a standard space. Structures of interest comprised temporopolar, entorhinal, perirhinal, parahippocampal cortices, hippocampus, and the amygdala. Segmentation was carried out with multiplanar assessment. There was no statistically significant left/right-sided asymmetry concerning any structure analyzed. Neither gender nor age influenced the volumes obtained. The coefficient of repeatability showed no significant difference of intra- and interobserver measurements. Imaging post-processing and simultaneous multiplanar view of high-resolution MRI facilitates volumetric assessment of the medial portion of the temporal lobe with strict adherence to anatomic landmarks. This protocol shows no significant inter- and intraobserver variations and thus is reliable for longitudinal studies.

  15. Novel 3D magnetic resonance elastography for the noninvasive diagnosis of advanced fibrosis in NAFLD: A prospective study

    PubMed Central

    Loomba, Rohit; Cui, Jeffrey; Wolfson, Tanya; Haufe, William; Hooker, Jonathan; Szeverenyi, Nikolaus; Ang, Brandon; Bhatt, Archana; Wang, Kang; Aryafar, Hamed; Behling, Cindy; Valasek, Mark A.; Lin, Grace Y.; Gamst, Anthony; Brenner, David A.; Yin, Meng; Glaser, Kevin J.; Ehman, Richard L.; Sirlin, Claude B.

    2016-01-01

    Objective Recent studies show two-dimensional (2D)-MRE is accurate in diagnosing advanced fibrosis (stages 3 and 4) in nonalcoholic fatty liver disease (NAFLD) patients. 3D-MRE is a more advanced version of the technology that can image shear-wave fields in 3D of the entire liver. The aim of this study was to prospectively compare the diagnostic accuracy of 3D-MRE and 2D-MRE for diagnosing advanced fibrosis in patients with biopsy-proven NAFLD. Design This cross-sectional analysis of a prospective study included 100 consecutive patients (56% women) with biopsy-proven NAFLD who also underwent MRE. Area under the receiver operating characteristic (AUROC) ana3lysis was performed to assess the accuracy of 2D and 3D-MRE in diagnosing advanced fibrosis. Results The mean (±sd) of age and BMI was 50.2 (±13.6) yrs and 32.1 (±5.0) kg/m2, respectively. The AUROC for diagnosing advanced fibrosis was 0.981 for 3D-MRE at 40 Hz, 0.927 for 3D-MRE at 60 Hz (standard shear-wave frequency), and 0.921 for 2D-MRE at 60 Hz (standard shear-wave frequency). At a threshold of 2.43 kPa, 3D-MRE at 40 Hz had sensitivity 1.0, specificity 0.94, positive predictive value 0.72, and negative predictive value 1.0 for diagnosing advanced fibrosis. 3D-MRE at 40 Hz had significantly higher AUROC (p<0.05) than 2D-MRE at 60 Hz for diagnosing advanced fibrosis. Conclusion Utilizing a prospective study design, we demonstrate that 3D MRE at 40 Hz has the highest diagnostic accuracy in diagnosing NAFLD advanced fibrosis. Both 2D and 3D-MRE at 60 Hz, the standard shear-wave frequency, are also highly accurate in diagnosing NAFLD advanced fibrosis. PMID:27002798

  16. Prenatal diagnosis of a patent urachus cyst with the use of 2D, 3D, 4D ultrasound and fetal magnetic resonance imaging.

    PubMed

    Fuchs, F; Picone, O; Levaillant, J M; Mabille, M; Mas, A E; Frydman, R; Senat, M V

    2008-01-01

    Patent urachus cyst is a rare umbilical anomaly, which is poorly detected prenatally and frequently confounded with pseudo bladder exstrophy or omphalocele. A 27-year-old woman was referred to our prenatal diagnosis centre at 18 weeks of gestation after diagnosis of a megabladder and 2 umbilical cord cysts. Subsequent 2D, 3D and 4D ultrasound examinations and fetal magnetic resonance imaging (MRI) revealed a typical umbilical cyst and an extra-abdominal cyst, communicating with the vertex of the fetal bladder through a small channel that increased in size when the fetus voided urine. Termination of pregnancy occured at 31 weeks because of associated cerebral septal agenesis, and autopsy confirmed the prenatal diagnosis of urachus cyst. Few cases of urachus cyst diagnosed prenatally are reported in literature, but none were associated with other extra-abdominal disorders and none used 3D, 4D and fetal MRI. Our case illustrated the efficiency in prenatal diagnosis of 3D and 4D ultrasound examinations. This could help pediatrician surgeons to explain to a couple about neonatal surgical repair and plastic reconstruction in the prenatal period.

  17. Right Ventricular Strain, Torsion, and Dyssynchrony in Healthy Subjects using 3D Spiral Cine DENSE Magnetic Resonance Imaging.

    PubMed

    Suever, Jonathan; Wehner, Gregory; Jing, Linyuan; Powell, David; Hamlet, Sean; Grabau, Jonathan; Mojsejenko, Dimitri; Andres, Kristin; Haggerty, Christopher; Fornwalt, Brandon

    2016-12-29

    Mechanics of the left ventricle (LV) are important indicators of cardiac function. The role of right ventricular (RV) mechanics is largely unknown due to the technical limitations of imaging its thin wall and complex geometry and motion. By combining 3D Displacement Encoding with Stimulated Echoes (DENSE) with a post-processing pipeline that includes a local coordinate system, it is possible to quantify RV strain, torsion, and synchrony. In this study, we sought to characterize RV mechanics in 50 healthy individuals and compare these values to their LV counterparts. For each cardiac frame, 3D displacements were fit to continuous and differentiable radial basis functions, allowing for the computation of the 3D Cartesian Lagrangian strain tensor at any myocardial point. The geometry of the RV was extracted via a surface fit to manually delineated endocardial contours. Throughout the RV, a local coordinate system was used to transform from a Cartesian strain tensor to a polar strain tensor. It was then possible to compute peak RV torsion as well as peak longitudinal and circumferential strain. A comparable analysis was performed for the LV. Dyssynchrony was computed from the standard deviation of regional activation times. Global circumferential strain was comparable between the RV and LV (-18.0% for both) while longitudinal strain was greater in the RV (-18.1% vs. -15.7%). RV torsion was comparable to LV torsion (6.2 vs. 7.1 degrees, respectively). Regional activation times indicated that the RV contracted later but more synchronously than the LV. 3D spiral cine DENSE combined with a post-processing pipeline that includes a local coordinate system can resolve both the complex geometry and 3D motion of the RV.

  18. Localization of Metal Electrodes in the Intact Rat Brain Using Registration of 3D Microcomputed Tomography Images to a Magnetic Resonance Histology Atlas1,2,3

    PubMed Central

    Borg, Jana Schaich; Vu, Mai-Anh; Badea, Cristian; Badea, Alexandra; Johnson, G. Allan

    2015-01-01

    Abstract Simultaneous neural recordings taken from multiple areas of the rodent brain are garnering growing interest because of the insight they can provide about spatially distributed neural circuitry. The promise of such recordings has inspired great progress in methods for surgically implanting large numbers of metal electrodes into intact rodent brains. However, methods for localizing the precise location of these electrodes have remained severely lacking. Traditional histological techniques that require slicing and staining of physical brain tissue are cumbersome and become increasingly impractical as the number of implanted electrodes increases. Here we solve these problems by describing a method that registers 3D computed tomography (CT) images of intact rat brains implanted with metal electrode bundles to a magnetic resonance imaging histology (MRH) atlas. Our method allows accurate visualization of each electrode bundle’s trajectory and location without removing the electrodes from the brain or surgically implanting external markers. In addition, unlike physical brain slices, once the 3D images of the electrode bundles and the MRH atlas are registered, it is possible to verify electrode placements from many angles by “reslicing” the images along different planes of view. Furthermore, our method can be fully automated and easily scaled to applications with large numbers of specimens. Our digital imaging approach to efficiently localizing metal electrodes offers a substantial addition to currently available methods, which, in turn, may help accelerate the rate at which insights are gleaned from rodent network neuroscience. PMID:26322331

  19. 3D localized 2D ultrafast J-resolved magnetic resonance spectroscopy: in vitro study on a 7 T imaging system.

    PubMed

    Roussel, T; Giraudeau, P; Ratiney, H; Akoka, S; Cavassila, S

    2012-02-01

    2D Magnetic Resonance Spectroscopy (MRS) is a well known tool for the analysis of complicated and overlapped MR spectra and was therefore originally used for structural analysis. It also presents a potential for biomedical applications as shown by an increasing number of works related to localized in vivo experiments. However, 2D MRS suffers from long acquisition times due to the necessary collection of numerous increments in the indirect dimension (t(1)). This paper presents the first 3D localized 2D ultrafast J-resolved MRS sequence, developed on a small animal imaging system, allowing the acquisition of a 3D localized 2D J-resolved MRS spectrum in a single scan. Sequence parameters were optimized regarding Signal-to-Noise ratio and spectral resolution. Sensitivity and spatial localization properties were characterized and discussed. An automatic post-processing method allowing the reduction of artifacts inherent to ultrafast excitation is also presented. This sequence offers an efficient signal localization and shows a great potential for in vivo dynamic spectroscopy.

  20. Evaluation of Metabolomic Changes as a Biomarker of Chondrogenic Differentiation in 3D-cultured Human Mesenchymal Stem Cells Using Proton (1H) Nuclear Magnetic Resonance Spectroscopy

    PubMed Central

    Jang, Moo-Young; Chun, Song-I; Mun, Chi-Woong; Hong, Kwan Soo; Shin, Jung-Woog

    2013-01-01

    Purpose The purpose of this study was to evaluate the metabolomic changes in 3D-cultured human mesenchymal stem cells (hMSCs) in alginate beads, so as to identify biomarkers during chondrogenesis using 1H nuclear magnetic resonance (NMR) spectroscopy. Materials and Methods hMSCs (2×106 cells/mL) were seeded into alginate beads, and chondrogenesis was allowed to progress for 15 days. NMR spectra of the chondrogenic hMSCs were obtained at 4, 7, 11, and 15 days using a 14.1-T (600-MHz) NMR with the water suppression sequence, zgpr. Real-Time polymerase chain reaction (PCR) was performed to confirm that that the hMSCs differentiated into chondrocytes and to analyze the metabolomic changes indicated by the NMR spectra. Results During chondrogenesis, changes were detected in several metabolomes as hMSC chondrogenesis biomarkers, e.g., fatty acids, alanine, glutamate, and phosphocholine. The metabolomic changes were compared with the Real-Time PCR results, and significant differences were determined using statistical analysis. We found that changes in metabolomes were closely related to biological reactions that occurred during the chondrogenesis of hMSCs. Conclusions In this study, we confirm that metabolomic changes detected by 1H-NMR spectroscopy during chondrogenic differentiation of 3D-cultured hMSCs in alginate beads can be considered as biomarkers of stem cell differentiation. PMID:24205199

  1. The effect of tumour size on drug transport and uptake in 3-D tumour models reconstructed from magnetic resonance images

    PubMed Central

    Zhan, Wenbo; Gedroyc, Wladyslaw

    2017-01-01

    Drug transport and its uptake by tumour cells are strongly dependent on tumour properties, which vary in different types of solid tumours. By simulating the key physical and biochemical processes, a numerical study has been carried out to investigate the transport of anti-cancer drugs in 3-D tumour models of different sizes. The therapeutic efficacy for each tumour is evaluated by using a pharmacodynamics model based on the predicted intracellular drug concentration. Simulation results demonstrate that interstitial fluid pressure and interstitial fluid loss vary non-linearly with tumour size. Transvascular drug exchange, driven by the concentration gradient of unbound drug between blood and interstitial fluid, is more efficient in small tumours, owing to the low spatial-mean interstitial fluid pressure and dense microvasculature. However, this has a detrimental effect on therapeutic efficacy over longer periods as a result of enhanced reverse diffusion of drug to the blood circulation after the cessation of drug infusion, causing more rapid loss of drug in small tumours. PMID:28212385

  2. Magnetic resonance imaging-targeted, 3D transrectal ultrasound-guided fusion biopsy for prostate cancer: Quantifying the impact of needle delivery error on diagnosis

    SciTech Connect

    Martin, Peter R.; Cool, Derek W.; Romagnoli, Cesare; Fenster, Aaron; Ward, Aaron D.

    2014-07-15

    Purpose: Magnetic resonance imaging (MRI)-targeted, 3D transrectal ultrasound (TRUS)-guided “fusion” prostate biopsy intends to reduce the ∼23% false negative rate of clinical two-dimensional TRUS-guided sextant biopsy. Although it has been reported to double the positive yield, MRI-targeted biopsies continue to yield false negatives. Therefore, the authors propose to investigate how biopsy system needle delivery error affects the probability of sampling each tumor, by accounting for uncertainties due to guidance system error, image registration error, and irregular tumor shapes. Methods: T2-weighted, dynamic contrast-enhanced T1-weighted, and diffusion-weighted prostate MRI and 3D TRUS images were obtained from 49 patients. A radiologist and radiology resident contoured 81 suspicious regions, yielding 3D tumor surfaces that were registered to the 3D TRUS images using an iterative closest point prostate surface-based method to yield 3D binary images of the suspicious regions in the TRUS context. The probabilityP of obtaining a sample of tumor tissue in one biopsy core was calculated by integrating a 3D Gaussian distribution over each suspicious region domain. Next, the authors performed an exhaustive search to determine the maximum root mean squared error (RMSE, in mm) of a biopsy system that gives P ≥ 95% for each tumor sample, and then repeated this procedure for equal-volume spheres corresponding to each tumor sample. Finally, the authors investigated the effect of probe-axis-direction error on measured tumor burden by studying the relationship between the error and estimated percentage of core involvement. Results: Given a 3.5 mm RMSE for contemporary fusion biopsy systems,P ≥ 95% for 21 out of 81 tumors. The authors determined that for a biopsy system with 3.5 mm RMSE, one cannot expect to sample tumors of approximately 1 cm{sup 3} or smaller with 95% probability with only one biopsy core. The predicted maximum RMSE giving P ≥ 95% for each

  3. Magnetic Properties of 3D Printed Toroids

    NASA Astrophysics Data System (ADS)

    Bollig, Lindsey; Otto, Austin; Hilpisch, Peter; Mowry, Greg; Nelson-Cheeseman, Brittany; Renewable Energy; Alternatives Lab (REAL) Team

    Transformers are ubiquitous in electronics today. Although toroidal geometries perform most efficiently, transformers are traditionally made with rectangular cross-sections due to the lower manufacturing costs. Additive manufacturing techniques (3D printing) can easily achieve toroidal geometries by building up a part through a series of 2D layers. To get strong magnetic properties in a 3D printed transformer, a composite filament is used containing Fe dispersed in a polymer matrix. How the resulting 3D printed toroid responds to a magnetic field depends on two structural factors of the printed 2D layers: fill factor (planar density) and fill pattern. In this work, we investigate how the fill factor and fill pattern affect the magnetic properties of 3D printed toroids. The magnetic properties of the printed toroids are measured by a custom circuit that produces a hysteresis loop for each toroid. Toroids with various fill factors and fill patterns are compared to determine how these two factors can affect the magnetic field the toroid can produce. These 3D printed toroids can be used for numerous applications in order to increase the efficiency of transformers by making it possible for manufacturers to make a toroidal geometry.

  4. Diagnostic performance of magnetic resonance imaging and 3D endoanal ultrasound in detection, staging and assessment post treatment, in anal cancer.

    PubMed

    Reginelli, Alfonso; Granata, Vincenza; Fusco, Roberta; Granata, Francesco; Rega, Daniela; Roberto, Luca; Pellino, Gianluca; Rotondo, Antonio; Selvaggi, Francesco; Izzo, Francesco; Petrillo, Antonella; Grassi, Roberto

    2017-02-01

    We compared Magnetic Resonance Imaging (MRI) and 3D Endoanal Ultrasound (EAUS) imaging performance to confirm anal carcinoma and to monitor treatment response.58 patients with anal cancer were retrospectively enrolled. All patients underwent clinical examination, anoscopic examination; EAUS and contrast-enhanced MRI study before and after treatment. Four radiologists evaluated the presence of lesions, using a 4-point confidence scale, features of the lesion and nodes on EAUS images, T1-weighted (T1-W), T2-weighted (T2-W) and diffusion-weighted images (DWI) signal intensity (SI), the apparent diffusion coefficient (ADC) map for nodes and lesion, as well as enhancement pattern during dynamic MRI were assessed.All lesions were detected by EAUS while MRI detected 93.1% of anal cancer. MRI showed a good correlation with EAUS, anoscopy and clinical examination. The residual tissue not showed significant difference in EAUS assessment and T2-W SI in pre and post treatment. We found significant difference in dynamic study, in SI of DWI, in ADC map and values among responder's patients in pre and post treatment. The neoplastic nodes were hypoecoic on EAUS, with hyperintense signal on T2-W sequences and hypointense signal on T1-W. The neoplastic nodes showed SI on DWI sequences and ADC value similar to anal cancer. We found significant difference in nodes status in pre and post therapy on DWI data.3D EAUS and MRI are accurate techniques in anal cancer staging, although EAUS is more accurate than MRI for T1 stage. MRI allows correct detection of neoplastic nodes and can properly stratify patients into responders or non responders.

  5. Histograms of Oriented 3D Gradients for Fully Automated Fetal Brain Localization and Robust Motion Correction in 3 T Magnetic Resonance Images

    PubMed Central

    Macnaught, Gillian; Denison, Fiona C.; Reynolds, Rebecca M.; Semple, Scott I.; Boardman, James P.

    2017-01-01

    Fetal brain magnetic resonance imaging (MRI) is a rapidly emerging diagnostic imaging tool. However, automated fetal brain localization is one of the biggest obstacles in expediting and fully automating large-scale fetal MRI processing. We propose a method for automatic localization of fetal brain in 3 T MRI when the images are acquired as a stack of 2D slices that are misaligned due to fetal motion. First, the Histogram of Oriented Gradients (HOG) feature descriptor is extended from 2D to 3D images. Then, a sliding window is used to assign a score to all possible windows in an image, depending on the likelihood of it containing a brain, and the window with the highest score is selected. In our evaluation experiments using a leave-one-out cross-validation strategy, we achieved 96% of complete brain localization using a database of 104 MRI scans at gestational ages between 34 and 38 weeks. We carried out comparisons against template matching and random forest based regression methods and the proposed method showed superior performance. We also showed the application of the proposed method in the optimization of fetal motion correction and how it is essential for the reconstruction process. The method is robust and does not rely on any prior knowledge of fetal brain development. PMID:28251155

  6. Resonant soft x-ray magnetic scattering from the 4f and 3d electrons in DyFe{sub 4}Al{sub 8}: Magnetic interactions in a cycloidal antiferromagnet

    SciTech Connect

    Beale, T. A. W.; Hatton, P. D.; Wilkins, S. B.; Abbamonte, P.; Stanescu, S.; Paixao, J. A.

    2007-05-01

    Soft x-ray resonant scattering has been used to examine the charge and magnetic interactions in the cycloidal antiferromagnetic compound DyFe{sub 4}Al{sub 8}. By tuning to the Dy M{sub 4} and M{sub 5} absorption edges and the Fe L{sub 2} and L{sub 3} absorption edges, we can directly observe the behavior of the Dy 4f and Fe 3d electron shells. Magnetic satellites surrounding the (110) Bragg peak were observed below 65 K. The diffraction peaks display complex spectra at the Dy M{sub 5} edge, indicative of a split 4f electron band. This is in contrast to the simple resonance observed at the Fe L{sub 3} absorption edge, which probes the Fe 3d electron shell. Temperature-dependent measurements detail the ordering of the magnetic moments on both the iron and the dysprosium antiferromagnetic cycloids. The ratio between the superlattice peak intensities of the Dy M{sub 4} and M{sub 5} absorption edges remained constant throughout the temperature range, in contrast to a previous study conducted at the Dy L{sub 2,3} edges. Our results demonstrate the ability of soft x-ray diffraction to separate the individual magnetic components in complicated multielement magnetic structures.

  7. Automatic Segmentation of the Eye in 3D Magnetic Resonance Imaging: A Novel Statistical Shape Model for Treatment Planning of Retinoblastoma

    SciTech Connect

    Ciller, Carlos; De Zanet, Sandro I.; Rüegsegger, Michael B.; Pica, Alessia; Sznitman, Raphael; Thiran, Jean-Philippe; Maeder, Philippe; Munier, Francis L.; Kowal, Jens H.; and others

    2015-07-15

    Purpose: Proper delineation of ocular anatomy in 3-dimensional (3D) imaging is a big challenge, particularly when developing treatment plans for ocular diseases. Magnetic resonance imaging (MRI) is presently used in clinical practice for diagnosis confirmation and treatment planning for treatment of retinoblastoma in infants, where it serves as a source of information, complementary to the fundus or ultrasonographic imaging. Here we present a framework to fully automatically segment the eye anatomy for MRI based on 3D active shape models (ASM), and we validate the results and present a proof of concept to automatically segment pathological eyes. Methods and Materials: Manual and automatic segmentation were performed in 24 images of healthy children's eyes (3.29 ± 2.15 years of age). Imaging was performed using a 3-T MRI scanner. The ASM consists of the lens, the vitreous humor, the sclera, and the cornea. The model was fitted by first automatically detecting the position of the eye center, the lens, and the optic nerve, and then aligning the model and fitting it to the patient. We validated our segmentation method by using a leave-one-out cross-validation. The segmentation results were evaluated by measuring the overlap, using the Dice similarity coefficient (DSC) and the mean distance error. Results: We obtained a DSC of 94.90 ± 2.12% for the sclera and the cornea, 94.72 ± 1.89% for the vitreous humor, and 85.16 ± 4.91% for the lens. The mean distance error was 0.26 ± 0.09 mm. The entire process took 14 seconds on average per eye. Conclusion: We provide a reliable and accurate tool that enables clinicians to automatically segment the sclera, the cornea, the vitreous humor, and the lens, using MRI. We additionally present a proof of concept for fully automatically segmenting eye pathology. This tool reduces the time needed for eye shape delineation and thus can help clinicians when planning eye treatment and confirming the extent of the tumor.

  8. Non-contrast 3D time-of-flight magnetic resonance angiography for visualization of intracranial aneurysms in patients with absolute contraindications to CT or MRI contrast.

    PubMed

    Yanamadala, Vijay; Sheth, Sameer A; Walcott, Brian P; Buchbinder, Bradley R; Buckley, Deidre; Ogilvy, Christopher S

    2013-08-01

    The preoperative evaluation of patients with intracranial aneurysms typically includes a contrast-enhanced vascular study, such as computed tomography angiography (CTA), magnetic resonance angiography (MRA), or digital subtraction angiography. However, there are numerous absolute and relative contraindications to the administration of imaging contrast agents, including pregnancy, severe contrast allergy, and renal insufficiency. Evaluation of patients with contrast contraindications thus presents a unique challenge. We identified three patients with absolute contrast contraindications who presented with intracranial aneurysms. One patient was pregnant, while the other two had previous severe anaphylactic reactions to iodinated contrast. Because of these contraindications to intravenous contrast, we performed non-contrast time-of-flight MRA with 3D reconstruction (TOF MRA with 3DR) with maximum intensity projections and volume renderings as part of the preoperative evaluation prior to successful open surgical clipping of the aneurysms. In the case of one paraclinoid aneurysm, a high-resolution non-contrast CT scan was also performed to assess the relationship of the aneurysm to the anterior clinoid process. TOF MRA with 3DR successfully identified the intracranial aneurysms and adequately depicted the surrounding microanatomy. Intraoperative findings were as predicted by the preoperative imaging studies. The aneurysms were successfully clip-obliterated, and the patients had uneventful post-operative courses. These cases demonstrate that non-contrast imaging is a viable modality to assess intracranial aneurysms as part of the surgical planning process in patients with contrast contraindications. TOF MRA with 3DR, in conjunction with high-resolution non-contrast CT when indicated, provides adequate visualization of the microanatomy of the aneurysm and surrounding structures.

  9. Short-echo 3D H-1 Magnetic Resonance Spectroscopic Imaging of patients with glioma at 7T for characterization of differences in metabolite levels

    PubMed Central

    Li, Yan; Larson, Peder; Chen, Albert P.; Lupo, Janine M.; Ozhinsky, Eugene; Kelley, Douglas; Chang, Susan M.; Nelson, Sarah J.

    2014-01-01

    Purpose The purpose of this study was to evaluate the feasibility of using a short echo time, 3D H-1 magnetic resonance spectroscopic imaging (MRSI) sequence at 7T to assess the metabolic signature of lesions for patients with glioma. Materials and Methods 29 patients with glioma were studied. MRSI data were obtained using CHESS water suppression, spectrally-selective adiabatic inversion-recovery pulses and automatically prescribed outer-volume-suppression for lipid suppression, and spin echo slice selection (TE=30ms). An interleaved flyback echo-planar trajectory was applied to shorten the total acquisition time (~10min). Relative metabolite ratios were estimated in tumor and in normal-appearing white and gray matter (NAWM, GM). Results Levels of glutamine, myo-inositol, glycine and glutathione relative to total creatine (tCr) were significantly increased in the T2 lesions for all tumor grades compared to those in the NAWM (p < 0.05), while N-acetyl aspartate to tCr were significantly decreased (p < 0.05). In grade 2 gliomas, level of total choline-containing-compounds to tCr was significantly increased (p = 0.0137), while glutamate to tCr was significantly reduced (p = 0.0012). Conclusion The improved sensitivity of MRSI and the increased number of metabolites that can be evaluated using 7T MR scanners is of interest for evaluating patients with glioma. This study has successfully demonstrated the application of a short-echo spin-echo MRSI sequence to detect characteristic differences in regions of tumor versus normal appearing brain. PMID:24935758

  10. High-Q 3D coaxial resonators for cavity QED

    NASA Astrophysics Data System (ADS)

    Yoon, Taekwan; Owens, John C.; Naik, Ravi; Lachapelle, Aman; Ma, Ruichao; Simon, Jonathan; Schuster, David I.

    Three-dimensional microwave resonators provide an alternative approach to transmission-line resonators used in most current circuit QED experiments. Their large mode volume greatly reduces the surface dielectric losses that limits the coherence of superconducting circuits, and the well-isolated and controlled cavity modes further suppress coupling to the environment. In this work, we focus on unibody 3D coaxial cavities which are only evanescently coupled and free from losses due to metal-metal interfaces, allowing us to reach extremely high quality-factors. We achieve quality-factor of up to 170 million using 4N6 Aluminum at superconducting temperatures, corresponding to an energy ringdown time of ~4ms. We extend our methods to other materials including Niobium, NbTi, and copper coated with Tin-Lead solder. These cavities can be further explored to study their properties under magnetic field or upon coupling to superconducting Josephson junction qubits, e.g. 3D transmon qubits. Such 3D cavity QED system can be used for quantum information applications, or quantum simulation in coupled cavity arrays.

  11. Four-dimensional Magnetic Resonance Imaging with 3D Radial Sampling and Self-gating based K-space Sorting: Early Clinical Experience on Pancreatic Cancer Patients

    PubMed Central

    Yang, Wensha; Fan, Zhaoyang; Tuli, Richard; Deng, Zixin; Pang, Jianing; Wachsman, Ashley; Reznik, Robert; Sandler, Howard; Li, Debiao; Fraass, Benedick A.

    2015-01-01

    Purpose Dynamic magnetic resonance imaging (MRI) has been used to characterize internal organ motion but real time acquisition is typically limited to 2 dimensions. Methods have been developed to reconstruct four dimensional MRI (4D-MRI) based on time-stamped 2D images or 2D K-space data. These methods suffer from anisotropic resolution and rebinning artifacts. We applied a novel self-gating K-space sorted 4D-MRI (SG-KS-4D-MRI) method to overcome these limitations and to monitor pancreatic tumor motion. Methods and Material Ten patients were imaged using 4D-CT, cine 2D-MRI and the SG-KS-4D-MRI, which is a spoiled gradient recalled echo (GRE) sequence with 3D radial-sampling K-space projections and 1D projection-based self-gating. Tumor volumes were defined on all phases in both 4D-MRI and 4D-CT and then compared. Results An isotropic resolution of 1.56 mm was achieved in the SG-KS-4D-MRI images, which showed superior soft tissue contrast to 4D-CT and appeared to be free of visible rebinning artifacts. The tumor motion trajectory cross-correlations between SG-KS-4D-MRI and cine 2D-MRI in SI, AP and ML directions were 0.93±0.03, 0.83±0.10 and 0.74±0.18, respectively. The tumor motion trajectories cross-correlations between SG-KS-4D-MRI and 4D-CT in SI, AP and ML directions were 0.91±0.06, 0.72±0.16 and 0.44±0.24, respectively. The average standard deviation of GTV volume (GTV_σ) calculated from the ten breathing phases were 0.81 cc and 1.02 cc for SG-KS-4D-MRI and 4D-CT (p=0.012). Conclusions A novel SG-KS-4D-MRI acquisition method capable of reconstructing rebinning artifact free high resolution 4D-MRI images was used to quantify pancreas tumor motion. The resultant pancreatic tumor motion trajectories agreed well with 2D-cine-MRI and 4D-CT. The pancreatic tumor volumes shown in the different phases for the SG-KS-4D-MRI were statistically significantly more consistent than those in the 4D-CT. PMID:26452571

  12. Quantification of Left Ventricular Linear, Areal and Volumetric Dimensions: A Phantom and in Vivo Comparison of 2-D and Real-Time 3-D Echocardiography with Cardiovascular Magnetic Resonance.

    PubMed

    Polte, Christian L; Lagerstrand, Kerstin M; Gao, Sinsia A; Lamm, Carl R; Bech-Hanssen, Odd

    2015-07-01

    Two-dimensional echocardiography and real-time 3-D echocardiography have been reported to underestimate human left ventricular volumes significantly compared with cardiovascular magnetic resonance. We investigated the ability of 2-D echocardiography, real-time 3-D echocardiography and cardiovascular magnetic resonance to delineate dimensions of increasing complexity (diameter-area-volume) in a multimodality phantom model and in vivo, with the aim of elucidating the main cause of underestimation. All modalities were able to delineate phantom dimensions with high precision. In vivo, 2-D and real-time 3-D echocardiography underestimated short-axis end-diastolic linear and areal and all left ventricular volumetric dimensions significantly compared with cardiovascular magnetic resonance, but not short-axis end-systolic linear and areal dimensions. Underestimation increased successively from linear to volumetric left ventricular dimensions. When analyzed according to the same principles, 2-D and real-time 3-DE echocardiography provided similar left ventricular volumes. In conclusion, echocardiographic underestimation of left ventricular dimensions is due mainly to inherent technical differences in the ability to differentiate trabeculated from compact myocardium. Identical endocardial border definition criteria are needed to minimize differences between the modalities and to ensure better comparability in clinical practice.

  13. Kinetic shielding of magnetic islands in 3-D equilibria

    NASA Astrophysics Data System (ADS)

    Hegna, C. C.

    2010-11-01

    Kinetic theory is employed to calculate corrections to analytic predictions of saturated magnetic islands due to pressure gradients in 3-D magnetic configurations. The theory calculates the dominant trapped particle response to 3-D field induced net bounce averaged radial drifts. The associated kinetic response describes plasma currents that flow within magnetic surfaces. In general, these currents have a component that resonates with the helical angle of the magnetic island and affect saturated island sizes through the parallel currents generated to satisfy quasineutrality. The resulting kinetic response generally opposes the effects of singular Pfirsch-Schlüter currents that arise at the rational surfaces of general 3-D MHD equilibria. Accounting for both the MHD and kinetic responses, self-consistent magnetic island widths are calculated using Ampere's law. The kinetic effect is largest at lowest collisionality suggesting high-β stellarators are more resilient to retaining flux surface integrity at high-temperatures than predictions from conventional MHD based theory would imply.

  14. Validation of Blood Volume Fraction Quantification with 3D Gradient Echo Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Porcine Skeletal Muscle.

    PubMed

    Hindel, Stefan; Söhner, Anika; Maaß, Marc; Sauerwein, Wolfgang; Möllmann, Dorothe; Baba, Hideo Andreas; Kramer, Martin; Lüdemann, Lutz

    2017-01-01

    The purpose of this study was to assess the accuracy of fractional blood volume (vb) estimates in low-perfused and low-vascularized tissue using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). The results of different MRI methods were compared with histology to evaluate the accuracy of these methods under clinical conditions. vb was estimated by DCE-MRI using a 3D gradient echo sequence with k-space undersampling in five muscle groups in the hind leg of 9 female pigs. Two gadolinium-based contrast agents (CA) were used: a rapidly extravasating, extracellular, gadolinium-based, low-molecular-weight contrast agent (LMCA, gadoterate meglumine) and an extracellular, gadolinium-based, albumin-binding, slowly extravasating blood pool contrast agent (BPCA, gadofosveset trisodium). LMCA data were evaluated using the extended Tofts model (ETM) and the two-compartment exchange model (2CXM). The images acquired with administration of the BPCA were used to evaluate the accuracy of vb estimation with a bolus deconvolution technique (BD) and a method we call equilibrium MRI (EqMRI). The latter calculates the ratio of the magnitude of the relaxation rate change in the tissue curve at an approximate equilibrium state to the height of the same area of the arterial input function (AIF). Immunohistochemical staining with isolectin was used to label endothelium. A light microscope was used to estimate the fractional vascular area by relating the vascular region to the total tissue region (immunohistochemical vessel staining, IHVS). In addition, the percentage fraction of vascular volume was determined by multiplying the microvascular density (MVD) with the average estimated capillary lumen, [Formula: see text], where d = 8μm is the assumed capillary diameter (microvascular density estimation, MVDE). Except for ETM values, highly significant correlations were found between most of the MRI methods investigated. In the cranial thigh, for example, the vb medians

  15. Validation of Blood Volume Fraction Quantification with 3D Gradient Echo Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Porcine Skeletal Muscle

    PubMed Central

    Söhner, Anika; Maaß, Marc; Sauerwein, Wolfgang; Möllmann, Dorothe; Baba, Hideo Andreas; Kramer, Martin; Lüdemann, Lutz

    2017-01-01

    The purpose of this study was to assess the accuracy of fractional blood volume (vb) estimates in low-perfused and low-vascularized tissue using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). The results of different MRI methods were compared with histology to evaluate the accuracy of these methods under clinical conditions. vb was estimated by DCE-MRI using a 3D gradient echo sequence with k-space undersampling in five muscle groups in the hind leg of 9 female pigs. Two gadolinium-based contrast agents (CA) were used: a rapidly extravasating, extracellular, gadolinium-based, low-molecular-weight contrast agent (LMCA, gadoterate meglumine) and an extracellular, gadolinium-based, albumin-binding, slowly extravasating blood pool contrast agent (BPCA, gadofosveset trisodium). LMCA data were evaluated using the extended Tofts model (ETM) and the two-compartment exchange model (2CXM). The images acquired with administration of the BPCA were used to evaluate the accuracy of vb estimation with a bolus deconvolution technique (BD) and a method we call equilibrium MRI (EqMRI). The latter calculates the ratio of the magnitude of the relaxation rate change in the tissue curve at an approximate equilibrium state to the height of the same area of the arterial input function (AIF). Immunohistochemical staining with isolectin was used to label endothelium. A light microscope was used to estimate the fractional vascular area by relating the vascular region to the total tissue region (immunohistochemical vessel staining, IHVS). In addition, the percentage fraction of vascular volume was determined by multiplying the microvascular density (MVD) with the average estimated capillary lumen, π(d2)2, where d = 8μm is the assumed capillary diameter (microvascular density estimation, MVDE). Except for ETM values, highly significant correlations were found between most of the MRI methods investigated. In the cranial thigh, for example, the vb medians (interquartile range

  16. Multimodal evaluation of 2-D and 3-D ultrasound, computed tomography and magnetic resonance imaging in measurements of the thyroid volume using universally applicable cross-sectional imaging software: a phantom study.

    PubMed

    Freesmeyer, Martin; Wiegand, Steffen; Schierz, Jan-Henning; Winkens, Thomas; Licht, Katharina

    2014-07-01

    A precise estimate of thyroid volume is necessary for making adequate therapeutic decisions and planning, as well as for monitoring therapy response. The goal of this study was to compare the precision of different volumetry methods. Thyroid-shaped phantoms were subjected to volumetry via 2-D and 3-D ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI). The 3-D US scans were performed using sensor navigation and mechanical sweeping methods. Volumetry calculation ensued with the conventional ellipsoid model and the manual tracing method. The study confirmed the superiority of manual tracing with CT and MRI volumetry of the thyroid, but extended this knowledge also to the superiority of the 3-D US method, regardless of whether sensor navigation or mechanical sweeping is used. A novel aspect was successful use of the same universally applicable cross-imaging software for all modalities.

  17. Dynamic Assessment of the Vaginal High Pressure Zone using High Definition Manometery, 3D -Ultrasound and Magnetic Resonance Imaging of the Pelvic Floor Muscles

    PubMed Central

    Raizada, Varuna; Bhargava, Valmik; Jung, Sung-Ae; Karstens, Anna; Pretorius, Dolores; Krysl, Petr; Mittal, Ravinder K

    2010-01-01

    Aims We used a novel technique, high definition manometry (HDM) that utilizes 256 tactile sensitive micro-transducers to define the characteristics of vaginal high-pressure zone. Methods 16 nullipara asymptomatic women were studied using HDM, transperineal 2D dynamic ultrasound and dynamic magnetic resonance (MR) imaging. Results Vaginal high-pressure zone revealed higher contact pressures in anterior and posterior compared to lateral directions, both at rest and squeeze. At rest, anterior pressure cluster is located 10 mm cephalad to posterior pressure cluster; with squeeze the latter moves in the cranial direction by 7 mm. Ultrasound and MR images reveal that the anorectal angle moves cephalad and ventrally during squeeze. Cephalad movement of posterior pressure cluster during squeeze is similar to the cranial movement of anorectal angle. Conclusions We propose that the vaginal high-pressure zone represents the constrictor function and cranial movement of the posterior pressure cluster represents the elevator function of pelvic floor. PMID:20462564

  18. Improved border sharpness of post-infarct scar by a novel self-navigated free-breathing high-resolution 3D whole-heart inversion recovery magnetic resonance approach.

    PubMed

    Rutz, Tobias; Piccini, Davide; Coppo, Simone; Chaptinel, Jerome; Ginami, Giulia; Vincenti, Gabriella; Stuber, Matthias; Schwitter, Juerg

    2016-12-01

    The border zone of post-infarction myocardial scar as identified by late gadolinium enhancement (LGE) has been identified as a substrate for arrhythmias and consequently, high-resolution 3D scar information is potentially useful for planning of electrophysiological interventions. This study evaluates the performance of a novel high-resolution 3D self-navigated free-breathing inversion recovery magnetic resonance pulse sequence (3D-SN-LGE) vs. conventional 2D breath-hold LGE (2D-LGE) with regard to sharpness of borders (SBorder) of post-infarction scar. Patients with post-infarction scar underwent two magnetic resonance examinations for conventional 2D-LGE and high-resolution 3D-SN-LGE acquisitions (both 15 min after 0.2 mmol/kg Gadobutrol IV) at 1.5T. In the prototype 3D-SN-LGE sequence, each ECG-triggered radial steady-state-free-precession read-out segment is preceded by a non-slice-selective inversion pulse. Scar volume and SBorder were assessed on 2D-LGE and matching reconstructed high-resolution 3D-SN-LGE short-axis slices. In 16 patients (four females, 58 ± 10y) all scars visualized by 2D-LGE could be identified on 3D-SN-LGE (time between 2D-LGE and 3D-SN-LGE 48 ± 53 days). A good agreement of scar volume by 3D-SN-LGE vs. 2D-LGE was found (Bland-Altman: -3.7 ± 3.4 ml, correlation: r = 0.987, p < 0.001) with a small difference in scar volume (20.5 (15.8, 35.2) ml vs. 24.5 (20.0, 41.9)) ml, respectively, p = 0.002] and a good intra- and interobserver variability (1.1 ± 4.1 and -1.1 ± 11.9 ml, respectively). SBorder of border "scar to non-infarcted myocardium" was superior on 3D-SN-LGE vs. 2D-LGE: 0.180 ± 0.044 vs. 0.083 ± 0.038, p < 0.001. Detection and quantification of myocardial scar by 3D-SN-LGE is feasible and accurate in comparison to 2D-LGE. The high spatial resolution of the 3D sequence improves delineation of scar borders.

  19. 3-D magnetic field calculations for wiggglers using MAGNUS-3D

    SciTech Connect

    Pissanetzky, S.; Tompkins, P.

    1988-01-01

    The recent but steady trend toward increased magnetic and geometric complexity in the design of wigglers and undulators, of which tapered wigglers, hybrid structures, laced electromagnetic wigglers, magnetic cladding, twisters and magic structures are examples, has caused a need for reliable 3-D computer models and a better understanding of the behavior of magnetic systems in three dimensions. The capabilities of the MAGNUS-3D Group of Programs are ideally suited to solve this class of problems and provide insight into 3-D effects. MAGNUS-3D can solve any problem of Magnetostatics involving permanent magnets, linear or nonlinear ferromagnetic materials and electric conductors of any shape in space. The magnetic properties of permanent magnets are described by the complete nonlinear demagnetization curve as provided by the manufacturer, or, at the user's choice, by a simpler approximation involving the coercive force, the residual induction and the direction of magnetization. The ferromagnetic materials are described by a magnetization table and an accurate interpolation relation. An internal library with properties of common industrial steels is available. The conductors are independent of the mesh and are described in terms of conductor elements from an internal library.

  20. Intervertebral Disc Swelling Demonstrated by 3D and Water Content Magnetic Resonance Analyses after a 3-Day Dry Immersion Simulating Microgravity

    PubMed Central

    Treffel, Loïc; Mkhitaryan, Karen; Gellee, Stéphane; Gauquelin-Koch, Guillemette; Gharib, Claude; Blanc, Stéphane; Millet, Catherine

    2016-01-01

    Background: Vertebral deconditioning is commonly experienced after space flight and simulation studies. Disc herniation is quadrupled after space flight. Purpose: The main hypothesis formulated by the authors is that microgravity results in intervertebral disc (IVD) swelling. Study Design: The aim of the study was to identify the morphological changes of the spine and their clinical consequences after simulated microgravity by 3-day dry immersion (DI). The experimental protocol was performed on 12 male volunteers using magnetic resonance imaging and spectroscopy before and after DI. Methods: All the experiment was financially supported by CNES (Centre national d'études spatiales i.e., French Space Agency). Results: We observed an increase in spine height of 1.5 ± 0.4 cm and a decrease in curvature, particularly for the lumbar region with a decrease of −4 ± 2.5°. We found a significant increase in IVD volume of +8 ± 9% at T12-L1 and +11 ± 9% at L5-S1. This phenomenon is likely associated with the increase in disc intervertebral water content (IWC), 17 ± 27%. During the 3 days in DI, 92% of the subjects developed back pain in the lumbar region below the diaphragmatic muscle. This clinical observation may be linked to the morphological changes of the spine. Conclusions: The morphological changes observed and, specifically, the disc swelling caused by increased IWC may contribute to understanding disc herniation after microgravity exposure. Our results confirmed the efficiency of the 3-day DI model to reproduce quickly the effects of microgravity on spine morphology. Our findings raise the question of the subject selection in spatial studies, especially studies about spine morphology and reconditioning programs after space flight. These results may contribute to a better understanding of the mechanisms underlying disc herniation and may serve as the basis to develop countermeasures for astronauts and to prevent IVD herniation and back pain on Earth. PMID

  1. An Open Source Image Processing Method to Quantitatively Assess Tissue Growth after Non-Invasive Magnetic Resonance Imaging in Human Bone Marrow Stromal Cell Seeded 3D Polymeric Scaffolds

    PubMed Central

    Leferink, Anne M.; Fratila, Raluca M.; Koenrades, Maaike A.; van Blitterswijk, Clemens A.; Velders, Aldrik; Moroni, Lorenzo

    2014-01-01

    Monitoring extracellular matrix (ECM) components is one of the key methods used to determine tissue quality in three-dimensional (3D) scaffolds for regenerative medicine and clinical purposes. This is even more important when multipotent human bone marrow stromal cells (hMSCs) are used, as it could offer a method to understand in real time the dynamics of stromal cell differentiation and eventually steer it into the desired lineage. Magnetic Resonance Imaging (MRI) is a promising tool to overcome the challenge of a limited transparency in opaque 3D scaffolds. Technical limitations of MRI involve non-uniform background intensity leading to fluctuating background signals and therewith complicating quantifications on the retrieved images. We present a post-imaging processing sequence that is able to correct for this non-uniform background intensity. To test the processing sequence we investigated the use of MRI for in vitro monitoring of tissue growth in three-dimensional poly(ethylene oxide terephthalate)–poly(butylene terephthalate) (PEOT/PBT) scaffolds. Results showed that MRI, without the need to use contrast agents, is a promising non-invasive tool to quantitatively monitor ECM production and cell distribution during in vitro culture in 3D porous tissue engineered constructs. PMID:25502022

  2. An open source image processing method to quantitatively assess tissue growth after non-invasive magnetic resonance imaging in human bone marrow stromal cell seeded 3D polymeric scaffolds.

    PubMed

    Leferink, Anne M; Fratila, Raluca M; Koenrades, Maaike A; van Blitterswijk, Clemens A; Velders, Aldrik; Moroni, Lorenzo

    2014-01-01

    Monitoring extracellular matrix (ECM) components is one of the key methods used to determine tissue quality in three-dimensional (3D) scaffolds for regenerative medicine and clinical purposes. This is even more important when multipotent human bone marrow stromal cells (hMSCs) are used, as it could offer a method to understand in real time the dynamics of stromal cell differentiation and eventually steer it into the desired lineage. Magnetic Resonance Imaging (MRI) is a promising tool to overcome the challenge of a limited transparency in opaque 3D scaffolds. Technical limitations of MRI involve non-uniform background intensity leading to fluctuating background signals and therewith complicating quantifications on the retrieved images. We present a post-imaging processing sequence that is able to correct for this non-uniform background intensity. To test the processing sequence we investigated the use of MRI for in vitro monitoring of tissue growth in three-dimensional poly(ethylene oxide terephthalate)-poly(butylene terephthalate) (PEOT/PBT) scaffolds. Results showed that MRI, without the need to use contrast agents, is a promising non-invasive tool to quantitatively monitor ECM production and cell distribution during in vitro culture in 3D porous tissue engineered constructs.

  3. Mapping of the C3d ligand binding site on complement receptor 2 (CR2/CD21) using nuclear magnetic resonance and chemical shift analysis.

    PubMed

    Kovacs, James M; Hannan, Jonathan P; Eisenmesser, Elan Z; Holers, V Michael

    2009-04-03

    Complement receptor 2 (CR2, CD21) is a cell membrane protein, with 15 or 16 extracellular short consensus repeats (SCRs), that promotes B lymphocyte responses and bridges innate and acquired immunity. The most distally located SCRs (SCR1-2) mediate the interaction of CR2 with its four known ligands (C3d, Epstein-Barr virus gp350, interferon-alpha, and CD23). Inhibitory monoclonal antibodies against SCR1-2 block binding of all ligands. To develop ligand-specific inhibitors that would also assist in identifying residues unique to each receptor-ligand interaction, phage were selected from randomly generated libraries by panning with recombinant SCR1-2, followed by specific ligand-driven elution. Derived peptides were tested by competition ELISA. One peptide, C3dp1 (APQHLSSQYSRT) exhibited ligand-specific inhibition at midmicromolar IC(50). C3d was titrated into (15)N-labeled SCR1-2, which revealed chemical shift changes indicative of specific intermolecular interactions. With backbone assignments made, the chemical shift changes were mapped onto the crystal structure of SCR1-2. With regard to C3d, the binding surface includes regions of SCR1, SCR2, and the inter-SCR linker, specifically residues Arg(13), Tyr(16), Arg(28), Tyr(29), Ser(32), Thr(34), Lys(48), Asp(56), Lys(57), Tyr(68), Arg(83), Gly(84), Asn(101), Asn(105), and Ser(109). SCR1 and SCR2 demonstrated distinct binding modes. The CR2 binding surface incorporating SCR1 is inconsistent with a previous x-ray CR2-C3d co-crystal analysis but consistent with mutagenesis, x-ray neutron scattering, and inhibitory monoclonal antibody epitope mapping. Titration with C3dp1 yielded chemical shift changes (Arg(13), Tyr(16), Thr(34), Lys(48), Asp(56), Lys(57), Tyr(68), Arg(83), Gly(84), Asn(105), and Ser(109)) overlapping with C3d, indicating that C3dp1 interacts at the same CR2 site as C3d.

  4. 3D and 4D magnetic susceptibility tomography based on complex MR images

    DOEpatents

    Chen, Zikuan; Calhoun, Vince D

    2014-11-11

    Magnetic susceptibility is the physical property for T2*-weighted magnetic resonance imaging (T2*MRI). The invention relates to methods for reconstructing an internal distribution (3D map) of magnetic susceptibility values, .chi. (x,y,z), of an object, from 3D T2*MRI phase images, by using Computed Inverse Magnetic Resonance Imaging (CIMRI) tomography. The CIMRI technique solves the inverse problem of the 3D convolution by executing a 3D Total Variation (TV) regularized iterative convolution scheme, using a split Bregman iteration algorithm. The reconstruction of .chi. (x,y,z) can be designed for low-pass, band-pass, and high-pass features by using a convolution kernel that is modified from the standard dipole kernel. Multiple reconstructions can be implemented in parallel, and averaging the reconstructions can suppress noise. 4D dynamic magnetic susceptibility tomography can be implemented by reconstructing a 3D susceptibility volume from a 3D phase volume by performing 3D CIMRI magnetic susceptibility tomography at each snapshot time.

  5. The Theoretical Foundation of 3D Alfvén Resonances: Normal Modes

    NASA Astrophysics Data System (ADS)

    Wright, Andrew N.; Elsden, Thomas

    2016-12-01

    We consider the resonant coupling of fast and Alfvén magnetohydrodynamic (MHD) waves in a 3D equilibrium. Numerical solutions to normal modes (\\propto \\exp (-iω t)) are presented, along with a theoretical framework to interpret them. The solutions we find are fundamentally different from those in 1D and 2D. In 3D there exists an infinite number of possible resonant solutions within a “Resonant Zone,” and we show how boundary conditions and locally 2D regions can favor particular solutions. A unique feature of the resonance in 3D is switching between different permissible solutions when the boundary of the Resonant Zone is encountered. The theoretical foundation that we develop relies upon recognizing that, in 3D, the orientation of the resonant surface will not align in a simple fashion with an equilibrium coordinate. We present a method for generating the Alfvén wave natural frequencies for an arbitrarily oriented Alfvén wave, which requires a careful treatment of scale factors describing the background magnetic field geometry.

  6. MRI (Magnetic Resonance Imaging)

    MedlinePlus

    ... and Procedures Medical Imaging MRI (Magnetic Resonance Imaging) MRI (Magnetic Resonance Imaging) Share Tweet Linkedin Pin it More sharing options ... usually given through an IV in the arm. MRI Research Programs at FDA Magnetic Resonance Imaging (MRI) ...

  7. 3D print of polymer bonded rare-earth magnets, and 3D magnetic field scanning with an end-user 3D printer

    NASA Astrophysics Data System (ADS)

    Huber, C.; Abert, C.; Bruckner, F.; Groenefeld, M.; Muthsam, O.; Schuschnigg, S.; Sirak, K.; Thanhoffer, R.; Teliban, I.; Vogler, C.; Windl, R.; Suess, D.

    2016-10-01

    3D print is a recently developed technique, for single-unit production, and for structures that have been impossible to build previously. The current work presents a method to 3D print polymer bonded isotropic hard magnets with a low-cost, end-user 3D printer. Commercially available isotropic NdFeB powder inside a PA11 matrix is characterized, and prepared for the printing process. An example of a printed magnet with a complex shape that was designed to generate a specific stray field is presented, and compared with finite element simulation solving the macroscopic Maxwell equations. For magnetic characterization, and comparing 3D printed structures with injection molded parts, hysteresis measurements are performed. To measure the stray field outside the magnet, the printer is upgraded to a 3D magnetic flux density measurement system. To skip an elaborate adjusting of the sensor, a simulation is used to calibrate the angles, sensitivity, and the offset of the sensor. With this setup, a measurement resolution of 0.05 mm along the z-axes is achievable. The effectiveness of our calibration method is shown. With our setup, we are able to print polymer bonded magnetic systems with the freedom of having a specific complex shape with locally tailored magnetic properties. The 3D scanning setup is easy to mount, and with our calibration method we are able to get accurate measuring results of the stray field.

  8. 3D lumped LC resonators as low mass axion haloscopes

    NASA Astrophysics Data System (ADS)

    McAllister, Ben T.; Parker, Stephen R.; Tobar, Michael E.

    2016-08-01

    The axion is a hypothetical particle considered to be the most economical solution to the strong C P problem. It can also be formulated as a compelling component of dark matter. The haloscope, a leading axion detection scheme, relies on the conversion of galactic halo axions into real photons inside a resonant cavity structure in the presence of a static magnetic field, where the generated photon frequency corresponds to the mass of the axion. For maximum sensitivity it is key that the central frequency of the cavity mode structure coincides with the frequency of the generated photon. As the mass of the axion is unknown, it is necessary to perform searches over a wide range of frequencies. Currently there are substantial regions of the promising preinflationary low-mass axion range without any viable proposals for experimental searches. We show that three-dimensional resonant LC circuits with separated magnetic and electric fields, commonly known as reentrant cavities, can be sensitive dark matter haloscopes in this region, with frequencies inherently lower than those achievable in the equivalent size of empty resonant cavity. We calculate the sensitivity and accessible axion mass range of these experiments, designing geometries to exploit and maximize the separated magnetic and electric coupling of the axion to the cavity mode.

  9. Multimaterial magnetically assisted 3D printing of composite materials

    PubMed Central

    Kokkinis, Dimitri; Schaffner, Manuel; Studart, André R.

    2015-01-01

    3D printing has become commonplace for the manufacturing of objects with unusual geometries. Recent developments that enabled printing of multiple materials indicate that the technology can potentially offer a much wider design space beyond unusual shaping. Here we show that a new dimension in this design space can be exploited through the control of the orientation of anisotropic particles used as building blocks during a direct ink-writing process. Particle orientation control is demonstrated by applying low magnetic fields on deposited inks pre-loaded with magnetized stiff platelets. Multimaterial dispensers and a two-component mixing unit provide additional control over the local composition of the printed material. The five-dimensional design space covered by the proposed multimaterial magnetically assisted 3D printing platform (MM-3D printing) opens the way towards the manufacturing of functional heterogeneous materials with exquisite microstructural features thus far only accessible by biological materials grown in nature. PMID:26494528

  10. Multimaterial magnetically assisted 3D printing of composite materials

    NASA Astrophysics Data System (ADS)

    Kokkinis, Dimitri; Schaffner, Manuel; Studart, André R.

    2015-10-01

    3D printing has become commonplace for the manufacturing of objects with unusual geometries. Recent developments that enabled printing of multiple materials indicate that the technology can potentially offer a much wider design space beyond unusual shaping. Here we show that a new dimension in this design space can be exploited through the control of the orientation of anisotropic particles used as building blocks during a direct ink-writing process. Particle orientation control is demonstrated by applying low magnetic fields on deposited inks pre-loaded with magnetized stiff platelets. Multimaterial dispensers and a two-component mixing unit provide additional control over the local composition of the printed material. The five-dimensional design space covered by the proposed multimaterial magnetically assisted 3D printing platform (MM-3D printing) opens the way towards the manufacturing of functional heterogeneous materials with exquisite microstructural features thus far only accessible by biological materials grown in nature.

  11. Free-Standing Magnetic Nanopillars for 3D Nanomagnet Logic

    PubMed Central

    2014-01-01

    Nanomagnet logic (NML) is a relatively new computation technology that uses arrays of shape-controlled nanomagnets to enable digital processing. Currently, conventional resist-based lithographic processes limit the design of NML circuitry to planar nanostructures with homogeneous thicknesses. Here, we demonstrate the focused electron beam induced deposition of Fe-based nanomaterial for magnetic in-plane nanowires and out-of-plane nanopillars. Three-dimensional (3D) NML was achieved based on the magnetic coupling between nanowires and nanopillars in a 3D array. Additionally, the same Fe-based nanomaterial was used to produce tilt-corrected high-aspect-ratio probes for the accurate magnetic force microscopy (MFM) analysis of the fabricated 3D NML gate arrays. The interpretation of the MFM measurements was supported by magnetic simulations using the Object Oriented MicroMagnetic Framework. Introducing vertical out-of-plane nanopillars not only increases the packing density of 3D NML but also introduces an extra magnetic degree of freedom, offering a new approach to input/output and processing functionalities in nanomagnetic computing. PMID:25296008

  12. Simulation of bootstrap current in 2D and 3D ideal magnetic fields in tokamaks

    NASA Astrophysics Data System (ADS)

    Raghunathan, M.; Graves, J. P.; Cooper, W. A.; Pedro, M.; Sauter, O.

    2016-09-01

    We aim to simulate the bootstrap current for a MAST-like spherical tokamak using two approaches for magnetic equilibria including externally caused 3D effects such as resonant magnetic perturbations (RMPs), the effect of toroidal ripple, and intrinsic 3D effects such as non-resonant internal kink modes. The first approach relies on known neoclassical coefficients in ideal MHD equilibria, using the Sauter (Sauter et al 1999 Phys. Plasmas 6 2834) expression valid for all collisionalities in axisymmetry, and the second approach being the quasi-analytic Shaing-Callen (Shaing and Callen 1983 Phys. Fluids 26 3315) model in the collisionless regime for 3D. Using the ideal free-boundary magnetohydrodynamic code VMEC, we compute the flux-surface averaged bootstrap current density, with the Sauter and Shaing-Callen expressions for 2D and 3D ideal MHD equilibria including an edge pressure barrier with the application of resonant magnetic perturbations, and equilibria possessing a saturated non-resonant 1/1 internal kink mode with a weak internal pressure barrier. We compare the applicability of the self-consistent iterative model on the 3D applications and discuss the limitations and advantages of each bootstrap current model for each type of equilibrium.

  13. Magnetism In 3d Transition Metals at High Pressures

    SciTech Connect

    Iota, V

    2006-02-09

    This research project examined the changes in electronic and magnetic properties of transition metals and oxides under applied pressures, focusing on complex relationship between magnetism and phase stability in these correlated electron systems. As part of this LDRD project, we developed new measurement techniques and adapted synchrotron-based electronic and magnetic measurements for use in the diamond anvil cell. We have performed state-of-the-art X-ray spectroscopy experiments at the dedicated high-pressure beamline HP-CAT (Sector 16 Advanced Photon Source, Argonne National Laboratory), maintained in collaboration with of University of Nevada, Las Vegas and Geophysical Laboratory of The Carnegie Institution of Washington. Using these advanced measurements, we determined the evolution of the magnetic order in the ferromagnetic 3d transition metals (Fe, Co and Ni) under pressure, and found that at high densities, 3d band broadening results in diminished long range magnetic coupling. Our experiments have allowed us to paint a unified picture of the effects of pressure on the evolution of magnetic spin in 3d electron systems. The technical and scientific advances made during this LDRD project have been reported at a number of scientific meetings and conferences, and have been submitted for publication in technical journals. Both the technical advances and the physical understanding of correlated systems derived from this LDRD are being applied to research on the 4f and 5f electron systems under pressure.

  14. Voltage controlled magnetism in 3d transitional metals

    NASA Astrophysics Data System (ADS)

    Wang, Weigang

    2015-03-01

    Despite having attracted much attention in multiferroic materials and diluted magnetic semiconductors, the impact of an electric field on the magnetic properties remains largely unknown in 3d transitional ferromagnets (FMs) until recent years. A great deal of effort has been focused on the voltage-controlled magnetic anisotropy (VCMA) effect where the modulation of anisotropy field is understood by the change of electron density among different d orbitals of FMs in the presence of an electric field. Here we demonstrate another approach to alter the magnetism by electrically controlling the oxidation state of the 3d FM at the FM/oxide interface. The thin FM film sandwiched between a heavy metal layer and a gate oxide can be reversibly changed from an optimally-oxidized state with a strong perpendicular magnetic anisotropy to a metallic state with an in-plane magnetic anisotropy, or to a fully-oxidized state with nearly zero magnetization, depending on the polarity and time duration of the applied electric fields. This is a voltage controlled magnetism (VCM) effect, where both the saturation magnetization and anisotropy field of the 3d FM layer can be simultaneously controlled by voltage in a non-volatile fashion. We will also discuss the impact of this VCM effect on magnetic tunnel junctions and spin Hall switching experiments. This work, in collaboration with C. Bi, Y.H. Liu, T. Newhouse-Illige, M. Xu, M. Rosales, J.W. Freeland, O. Mryasov, S. Zhang, and S.G.E. te Velthuis, was supported in part by NSF (ECCS-1310338) and by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA.

  15. 3D Magnetic inversion and remanence: solving the problem

    NASA Astrophysics Data System (ADS)

    Thomson, V.; Morris, W.

    2003-04-01

    3D inversion of surface magnetic data is a common processing technique when used in mineral exploration. The major drawback of most 3D inversion algorithms is that they assume that the surface magnetic anomaly is produced by induced magnetization and that there are no remanent magnetization or demagnetization effects present. This has a significant impact when modeling magnetic data that has remanent magnetization. The magnetic anomaly produced by a dipping subsurface body will be identical for a consistent relationship between the dip of the body and the dip of the magnetic vector, regardless of the actual dip of the magnetic body. For example, in the case where a subsurface body is dipping, such as a dipping dike, the dip estimated by the inversion routine will be correct only if induced magnetization is present. This has serious implications for mineral exploration. A solution to the remanence problem is to model the surface magnetic anomaly using a constrained 2D approach rather than 3D. Using a priori information on dip and strike length of a source body, it is possible to approximate the remanence direction and intensity. The 2D solutions can then be rendered into a 3D imaging package to create a model in 3D. A case study was performed on a mafic-ultramafic layered igneous intrusion located in Big Trout Lake, northwestern Ontario, Canada. Large layered igneous intrusions are known to have significant remanence. Like many other layered igneous intrusions such as the Bushveld Complex in South Africa, the Big Trout Lake Complex is highly prospective for Platinum Group Elements (PGEs). Intruded during Archean time, the Big Trout Lake Complex has been subsequently folded and faulted to near vertical. As a consequence of limited surface exposures, knowledge of layering within the pluton and the extent of deformation of the pluton is very limited. Newly acquired high-resolution aeromagnetic data shows a strongly mineralized horizon within the intrusion that

  16. Geometric accuracy of 3D coordinates of the Leksell stereotactic skull frame in 1.5 Tesla- and 3.0 Tesla-magnetic resonance imaging: a comparison of three different fixation screw materials

    PubMed Central

    Nakazawa, Hisato; Mori, Yoshimasa; Yamamuro, Osamu; Komori, Masataka; Shibamoto, Yuta; Uchiyama, Yukio; Tsugawa, Takahiko; Hagiwara, Masahiro

    2014-01-01

    We assessed the geometric distortion of 1.5-Tesla (T) and 3.0-T magnetic resonance (MR) images with the Leksell skull frame system using three types of cranial quick fixation screws (QFSs) of different materials—aluminum, aluminum with tungsten tip, and titanium—for skull frame fixation. Two kinds of acrylic phantoms were placed on a Leksell skull frame using the three types of screws, and were scanned with computed tomography (CT), 1.5-T MR imaging and 3.0-T MR imaging. The 3D coordinates for both strengths of MR imaging were compared with those for CT. The deviations of the measured coordinates at selected points (x = 50, 100 and 150; y = 50, 100 and 150) were indicated on different axial planes (z = 50, 75, 100, 125 and 150). The errors of coordinates with QFSs of aluminum, tungsten-tipped aluminum, and titanium were <1.0, 1.0 and 2.0 mm in the entire treatable area, respectively, with 1.5 T. In the 3.0-T field, the errors with aluminum QFSs were <1.0 mm only around the center, while the errors with tungsten-tipped aluminum and titanium were >2.0 mm in most positions. The geometric accuracy of the Leksell skull frame system with 1.5-T MR imaging was high and valid for clinical use. However, the geometric errors with 3.0-T MR imaging were larger than those of 1.5-T MR imaging and were acceptable only with aluminum QFSs, and then only around the central region. PMID:25034732

  17. Particle acceleration at 3D reconnecting magnetic separators

    NASA Astrophysics Data System (ADS)

    Threlfall, James; Neukirch, Thomas; Parnell, Clare; Stevenson, Julie

    2015-04-01

    We present results of test particle orbit calculations in three different environments which model separator reconnection in three dimensions. The test particle (electron and proton) orbits are calculated using the relativistic guiding centre approximation. We investigate test particle orbits in a time-dependent (analytical) electro-magnetic field configuration [detailed in Threlfall et al. (A&A, in press); arXiv:1410.6465]. These results are also compared with orbits based upon large-scale 3D MHD simulations of both a single reconnecting magnetic separator and an observationally driven 3D model of a solar active region which contains several topological features of interest, including separators. We discuss how the test-particle orbits and the energy gain depend on the initial conditions, and how observations (for example, of solar flares) may be used to constrain model parameters.

  18. Note: 3D printed spheroid for uniform magnetic field generation

    NASA Astrophysics Data System (ADS)

    Öztürk, Y.; Aktaş, B.

    2016-10-01

    This article is focused on a novel and practical production method for a uniform magnetic field generator. The method involves building of a surface coil template using a desktop 3D printer and winding of a conducting wire onto the structure using surface grooves as a guide. Groove pattern was based on the parametric spheroidal helical coil formula. The coil was driven by a current source and the magnetic field inside was measured using a Hall probe placed into the holes on the printed structure. The measurements are found to be in good agreement with our finite element analysis results and indicate a fairly uniform field inside.

  19. Magnetism in a graphene-4 f -3 d hybrid system

    NASA Astrophysics Data System (ADS)

    Huttmann, Felix; Klar, David; Atodiresei, Nicolae; Schmitz-Antoniak, Carolin; Smekhova, Alevtina; Martínez-Galera, Antonio J.; Caciuc, Vasile; Bihlmayer, Gustav; Blügel, Stefan; Michely, Thomas; Wende, Heiko

    2017-02-01

    We create an interface of graphene with a metallic and magnetic support that leaves its electronic structure largely intact. This is achieved by exposing epitaxial graphene on ferromagnetic thin films of Co and Ni to vapor of the rare earth metal Eu at elevated temperatures, resulting in the intercalation of an Eu monolayer in between graphene and its substrate. The system is atomically well defined, with the Eu monolayer forming a (√{3 }×√{3 }) R 30∘ superstructure with respect to the graphene lattice. Thereby, we avoid the strong hybridization with the (Ni,Co) substrate 3 d states that otherwise drastically modify the electronic structure of graphene. This picture is suggested by our x-ray absorption spectroscopy measurements which show that after Eu intercalation the empty 2 p states of C atoms resemble more the ones measured for graphite in contrast to graphene directly bound to 3 d ferromagnetic substrates. We use x-ray magnetic circular dichroism at the Co and Ni L2 ,3 and Eu M4 ,5 as an element-specific probe to investigate magnetism in these systems. An antiferromagnetic coupling between Eu and Co/Ni moments is found, which is so strong that a magnetic moment of the Eu layer can be detected at room temperature. Density functional theory calculations confirm the antiferromagnetic coupling and provide an atomic insight into the magnetic coupling mechanism.

  20. Cardiovascular Magnetic Resonance Imaging

    NASA Astrophysics Data System (ADS)

    Pelc, Norbert

    2000-03-01

    Cardiovascular diseases are a major source of morbidity and mortality in the United States. Early detection of disease can often be used to improved outcomes, either through direct interventions (e.g. surgical corrections) or by causing the patient to modify his or her behavior (e.g. smoking cessation or dietary changes). Ideally, the detection process should be noninvasive (i.e. it should not be associated with significant risk). Magnetic Resonance Imaging (MRI) refers to the formation of images by localizing NMR signals, typically from protons in the body. As in other applications of NMR, a homogeneous static magnetic field ( ~0.5 to 4 T) is used to create ``longitudinal" magnetization. A magnetic field rotating at the Larmor frequency (proportional to the static field) excites spins, converting longitudinal magnetization to ``transverse" magnetization and generating a signal. Localization is performed using pulsed gradients in the static field. MRI can produce images of 2-D slices, 3-D volumes, time-resolved images of pseudo-periodic phenomena such as heart function, and even real-time imaging. It is also possible to acquire spatially localized NMR spectra. MRI has a number of advantages, but perhaps the most fundamental is the richness of the contrast mechanisms. Tissues can be differentiated by differences in proton density, NMR properties, and even flow or motion. We also have the ability to introduce substances that alter NMR signals. These contrast agents can be used to enhance vascular structures and measure perfusion. Cardiovascular MRI allows the reliable diagnosis of important conditions. It is possible to image the blood vessel tree, quantitate flow and perfusion, and image cardiac contraction. Fundamentally, the power of MRI as a diagnostic tool stems from the richness of the contrast mechanisms and the flexibility in control of imaging parameters.

  1. Bifurcation to 3D helical magnetic equilibrium in an axisymmetric toroidal device.

    PubMed

    Bergerson, W F; Auriemma, F; Chapman, B E; Ding, W X; Zanca, P; Brower, D L; Innocente, P; Lin, L; Lorenzini, R; Martines, E; Momo, B; Sarff, J S; Terranova, D

    2011-12-16

    We report the first direct measurement of the internal magnetic field structure associated with a 3D helical equilibrium generated spontaneously in the core of an axisymmetric toroidal plasma containment device. Magnetohydrodynamic equilibrium bifurcation occurs in a reversed-field pinch when the innermost resonant magnetic perturbation grows to a large amplitude, reaching up to 8% of the mean field strength. Magnetic topology evolution is determined by measuring the Faraday effect, revealing that, as the perturbation grows, toroidal symmetry is broken and a helical equilibrium is established.

  2. Supramolecular 3d-4f single-molecule magnet architectures.

    PubMed

    Schmitz, Sebastian; van Leusen, Jan; Izarova, Natalya V; Lan, Yanhua; Wernsdorfer, Wolfgang; Kögerler, Paul; Monakhov, Kirill Yu

    2016-10-18

    The nanosized self-assemblies {[{Ln(III)}{H2O⊂CrLn}]2(H2O)} (Ln = Dy, 1 and Tb, 2) based on new 3d-4f mixed-metal coordination topologies are formed via extensive intramolecular hydrogen bonding that is directed by enclosed water molecules. Compounds 1 and 2 show single-molecule magnet characteristics manifested by hysteresis loops up to 1.6 K (Ueff = 8.3 cm(-1)) and 1 K (Ueff = 3.4 cm(-1)), respectively.

  3. Magnetically Defined Qubits on 3D Topological Insulators

    NASA Astrophysics Data System (ADS)

    Ferreira, Gerson J.; Loss, Daniel

    2013-09-01

    We explore potentials that break time-reversal symmetry to confine the surface states of 3D topological insulators into quantum wires and quantum dots. A magnetic domain wall on a ferromagnet insulator cap layer provides interfacial states predicted to show the quantum anomalous Hall effect (QAHE). Here, we show that confinement can also occur at magnetic domain heterostructures, with states extended in the inner domain, as well as interfacial QAHE states at the surrounding domain walls. The proposed geometry allows the isolation of the wire and dot from spurious circumventing surface states. For the quantum dots, we find that highly spin-polarized quantized QAHE states at the dot edge constitute a promising candidate for quantum computing qubits.

  4. Magnetically Defined Qubits on 3D Topological Insulators

    NASA Astrophysics Data System (ADS)

    Ferreira, Gerson J.; Loss, Daniel

    2014-03-01

    We explore potentials that break time-reversal symmetry to confine the surface states of 3D topological insulators into quantum wires and quantum dots. A magnetic domain wall on a ferromagnet insulator cap layer provides interfacial states predicted to show the quantum anomalous Hall effect. Here, we show that confinement can also occur at magnetic domain heterostructures, with states extended in the inner domain, as well as interfacial QAHE states at the surrounding domain walls. The proposed geometry allows the isolation of the wire and dot from spurious circumventing surface states. For the quantum dots, we find that highly spin-polarized quantized QAHE states at the dot edge constitute a promising candidate for quantum computing qubits. See [Ferreira and Loss, Phys. Rev. Lett. 111, 106802 (2013)]. We explore potentials that break time-reversal symmetry to confine the surface states of 3D topological insulators into quantum wires and quantum dots. A magnetic domain wall on a ferromagnet insulator cap layer provides interfacial states predicted to show the quantum anomalous Hall effect. Here, we show that confinement can also occur at magnetic domain heterostructures, with states extended in the inner domain, as well as interfacial QAHE states at the surrounding domain walls. The proposed geometry allows the isolation of the wire and dot from spurious circumventing surface states. For the quantum dots, we find that highly spin-polarized quantized QAHE states at the dot edge constitute a promising candidate for quantum computing qubits. See [Ferreira and Loss, Phys. Rev. Lett. 111, 106802 (2013)]. We acknowledge support from the Swiss NSF, NCCR Nanoscience, NCCR QSIT, and the Brazillian Research Support Center Initiative (NAP Q-NANO) from Pró-Reitoria de Pesquisa (PRP/USP).

  5. Observation of a 3D Magnetic Null Point

    NASA Astrophysics Data System (ADS)

    Romano, P.; Falco, M.; Guglielmino, S. L.; Murabito, M.

    2017-03-01

    We describe high-resolution observations of a GOES B-class flare characterized by a circular ribbon at the chromospheric level, corresponding to the network at the photospheric level. We interpret the flare as a consequence of a magnetic reconnection event that occurred at a three-dimensional (3D) coronal null point located above the supergranular cell. The potential field extrapolation of the photospheric magnetic field indicates that the circular chromospheric ribbon is cospatial with the fan footpoints, while the ribbons of the inner and outer spines look like compact kernels. We found new interesting observational aspects that need to be explained by models: (1) a loop corresponding to the outer spine became brighter a few minutes before the onset of the flare; (2) the circular ribbon was formed by several adjacent compact kernels characterized by a size of 1″–2″ (3) the kernels with a stronger intensity emission were located at the outer footpoint of the darker filaments, departing radially from the center of the supergranular cell; (4) these kernels started to brighten sequentially in clockwise direction; and (5) the site of the 3D null point and the shape of the outer spine were detected by RHESSI in the low-energy channel between 6.0 and 12.0 keV. Taking into account all these features and the length scales of the magnetic systems involved in the event, we argue that the low intensity of the flare may be ascribed to the low amount of magnetic flux and to its symmetric configuration.

  6. Analysis of a 3-D system function measured for magnetic particle imaging.

    PubMed

    Rahmer, Jürgen; Weizenecker, Jürgen; Gleich, Bernhard; Borgert, Jörn

    2012-06-01

    Magnetic particle imaging (MPI) is a new tomographic imaging approach that can quantitatively map magnetic nanoparticle distributions in vivo. It is capable of volumetric real-time imaging at particle concentrations low enough to enable clinical applications. For image reconstruction in 3-D MPI, a system function (SF) is used, which describes the relation between the acquired MPI signal and the spatial origin of the signal. The SF depends on the instrumental configuration, the applied field sequence, and the magnetic particle characteristics. Its properties reflect the quality of the spatial encoding process. This work presents a detailed analysis of a measured SF to give experimental evidence that 3-D MPI encodes information using a set of 3-D spatial patterns or basis functions that is stored in the SF. This resembles filling 3-D k-space in magnetic resonance imaging, but is faster since all information is gathered simultaneously over a broad acquisition bandwidth. A frequency domain analysis shows that the finest structures that can be encoded with the presented SF are as small as 0.6 mm. SF simulations are performed to demonstrate that larger particle cores extend the set of basis functions towards higher resolution and that the experimentally observed spatial patterns require the existence of particles with core sizes of about 30 nm in the calibration sample. A simple formula is presented that qualitatively describes the basis functions to be expected at a certain frequency.

  7. The principles of magnetic resonance.

    PubMed

    Longmore, D B

    1989-10-01

    Magnetic Resonance (MR), which has no known biological hazard, is capable of producing high resolution thin tomographic images in any plane and blocks of 3-dimensional information. It can be used to study blood flow and to gain information about the composition of important materials seen and quantified on dimensionally accurate images. The MR image is a thin tomographic slice or a true three dimensional block of data which can be reconstructed in any desired way rather than a shadowgram of all the structures in the beam. It is the only imaging technique which can acquire data in a 3-dimensional format. CT images can be reconstructed to form a pseudo 3-D image or a hologram but the flexibility conferred by acquiring the data as a true 3-D block gives many advantages. The spatial resolution of MR images are theoretically those of low powered microscopy, the practical limits with the present generation of equipment are voxel sizes of one third by one third by two millimetres. The term Magnetic Resonance Imaging (MRI) is used commonly, particularly in the USA, avoiding association with the term, nuclear, and emphasizing the imaging potential of the technique. The terms Nuclear Magnetic Resonance (NMR) or Magnetic Resonance (MR) more correctly describe the most powerful diagnostic instrument yet devised. The simplified description of the phenomena involved in MR which follows is intended to be comprehensive and does not require foreknowledge of classical physics, quantum mechanics, fluency with mathematical formulae or an understanding of image reconstruction. There are many explanations of MR, some omitting the more difficult concepts. An accurate, comprehensive description is found on the textbook on MR by Gadian, Nuclear Magnetic Resonance and its Applications for Living Systems (Oxford University Press, 1982).

  8. MagicFinger: 3D Magnetic Fingerprints for Indoor Location

    PubMed Central

    Carrillo, Daniel; Moreno, Victoria; Úbeda, Benito; Skarmeta, Antonio F.

    2015-01-01

    Given the indispensable role of mobile phones in everyday life, phone-centric sensing systems are ideal candidates for ubiquitous observation purposes. This paper presents a novel approach for mobile phone-centric observation applied to indoor location. The approach involves a location fingerprinting methodology that takes advantage of the presence of magnetic field anomalies inside buildings. Unlike existing work on the subject, which uses the intensity of magnetic field for fingerprinting, our approach uses all three components of the measured magnetic field vectors to improve accuracy. By using adequate soft computing techniques, it is possible to adequately balance the constraints of common solutions. The resulting system does not rely on any infrastructure devices and therefore is easy to manage and deploy. The proposed system consists of two phases: the offline phase and the online phase. In the offline phase, magnetic field measurements are taken throughout the building, and 3D maps are generated. Then, during the online phase, the user's location is estimated through the best estimator for each zone of the building. Experimental evaluations carried out in two different buildings confirm the satisfactory performance of indoor location based on magnetic field vectors. These evaluations provided an error of (11.34 m, 4.78 m) in the (x, y) components of the estimated positions in the first building where the experiments were carried out, with a standard deviation of (3.41 m, 4.68 m); and in the second building, an error of (4 m, 2.98 m) with a deviation of (2.64 m, 2.33 m). PMID:26184230

  9. 3D simulation of silicon micro-ring resonator with Comsol

    NASA Astrophysics Data System (ADS)

    Degtyarev, S. A.; Podlipnov, V. V.; Verma, Payal; Khonina, S. N.

    2016-12-01

    In this paper we provide 3d full-vector static electromagnetic simulation of silicon micro-ring resonator operating. We show that geometrical and scalar approaches are not sufficiently accurate for calculating resonator parameters. Quite strong dependence of ring resonator radius on waveguide width is revealed.

  10. Designing bioinspired composite reinforcement architectures via 3D magnetic printing

    NASA Astrophysics Data System (ADS)

    Martin, Joshua J.; Fiore, Brad E.; Erb, Randall M.

    2015-10-01

    Discontinuous fibre composites represent a class of materials that are strong, lightweight and have remarkable fracture toughness. These advantages partially explain the abundance and variety of discontinuous fibre composites that have evolved in the natural world. Many natural structures out-perform the conventional synthetic counterparts due, in part, to the more elaborate reinforcement architectures that occur in natural composites. Here we present an additive manufacturing approach that combines real-time colloidal assembly with existing additive manufacturing technologies to create highly programmable discontinuous fibre composites. This technology, termed as `3D magnetic printing', has enabled us to recreate complex bioinspired reinforcement architectures that deliver enhanced material performance compared with monolithic structures. Further, we demonstrate that we can now design and evolve elaborate reinforcement architectures that are not found in nature, demonstrating a high level of possible customization in discontinuous fibre composites with arbitrary geometries.

  11. Designing bioinspired composite reinforcement architectures via 3D magnetic printing

    PubMed Central

    Martin, Joshua J.; Fiore, Brad E.; Erb, Randall M.

    2015-01-01

    Discontinuous fibre composites represent a class of materials that are strong, lightweight and have remarkable fracture toughness. These advantages partially explain the abundance and variety of discontinuous fibre composites that have evolved in the natural world. Many natural structures out-perform the conventional synthetic counterparts due, in part, to the more elaborate reinforcement architectures that occur in natural composites. Here we present an additive manufacturing approach that combines real-time colloidal assembly with existing additive manufacturing technologies to create highly programmable discontinuous fibre composites. This technology, termed as ‘3D magnetic printing', has enabled us to recreate complex bioinspired reinforcement architectures that deliver enhanced material performance compared with monolithic structures. Further, we demonstrate that we can now design and evolve elaborate reinforcement architectures that are not found in nature, demonstrating a high level of possible customization in discontinuous fibre composites with arbitrary geometries. PMID:26494282

  12. Resonant x-ray scattering in 3d-transition-metal oxides: Anisotropy and charge orderings

    NASA Astrophysics Data System (ADS)

    Subías, G.; García, J.; Blasco, J.; Herrero-Martín, J.; Sánchez, M. C.

    2009-11-01

    The structural, magnetic and electronic properties of transition metal oxides reflect in atomic charge, spin and orbital degrees of freedom. Resonant x-ray scattering (RXS) allows us to perform an accurate investigation of all these electronic degrees. RXS combines high-Q resolution x-ray diffraction with the properties of the resonance providing information similar to that obtained by atomic spectroscopy (element selectivity and a large enhancement of scattering amplitude for this particular element and sensitivity to the symmetry of the electronic levels through the multipole electric transitions). Since electronic states are coupled to the local symmetry, RXS reveals the occurrence of symmetry breaking effects such as lattice distortions, onset of electronic orbital ordering or ordering of electronic charge distributions. We shall discuss the strength of RXS at the K absorption edge of 3d transition-metal oxides by describing various applications in the observation of local anisotropy and charge disproportionation. Examples of these resonant effects are (I) charge ordering transitions in manganites, Fe3O4 and ferrites and (II) forbidden reflections and anisotropy in Mn3+ perovskites, spinel ferrites and cobalt oxides. In all the studied cases, the electronic (charge and/or anisotropy) orderings are determined by the structural distortions.

  13. Torque-mixing Magnetic Resonance Spectroscopy

    NASA Astrophysics Data System (ADS)

    Losby, Joseph; Fani Sani, Fatemeh; Grandmont, Dylan; Diao, Zhu; Belov, Miro; Burgess, Jacob; Compton, Shawn; Hiebert, Wayne; Vick, Doug; Mohammad, Kaveh; Salimi, Elham; Bridges, Gregory; Thomson, Douglas; Freeman, Mark

    A universal, mechanical torque method for magnetic resonance spectroscopy is presented. In analogy to resonance detection by induction, a signal proportional to the transverse component of a precessing dipole moment can be measured as a pure mechanical torque in broadband, frequency-swept spectroscopy. Comprehensive electron spin resonance of a single-crystal, mesoscopic yttrium iron garnet disk at room temperature are presented to demonstrate the method. The rich detail allows analysis of even complex 3D spin textures.

  14. 3-D, Impulsive Magnetic Reconnection in a Laboratory Plasma (Invited)

    NASA Astrophysics Data System (ADS)

    Dorfman, S. E.; Ji, H.; Yamada, M.; Yoo, J.; Myers, C. E.; Roytershteyn, V.; Daughton, W. S.; Jara-Almonte, J.

    2013-12-01

    Magnetic reconnection is a fundamental plasma process involving the efficient conversion of magnetic field energy to plasma kinetic energy through changing field line topology. In many space and astrophysical systems, including the solar surface and the Earth's magnetotail, reconnection is not only fast, but also impulsive; in other words, a slow buildup phase is followed by a comparatively quick release of magnetic energy. An important question in the literature is if these examples of impulsive reconnection can be described by a two-dimensional model with no variation in the out-of-plane direction or if impulsive reconnection is fundamentally three-dimensional. Events observed on the Magnetic Reconnection Experiment (MRX) are characterized by large local gradients in the third direction and cannot be explained by 2-D models [1]. Detailed measurements show that the ejection of flux rope structures from the current sheet plays a key role in these events. By contrast, even though electromagnetic fluctuations in the lower hybrid frequency range are also observed concurrently with the impulsive behavior, they are not the key physics responsible. Furthermore, an important discrepancy in the layer width and force balance between the collisionless regime of MRX and kinetic simulations [2-4] persists when the fluctuations are small or absent, implying that they are not the cause of the wider electron layers observed in the experiment [5]. These wider layers may instead be due to the formation of flux ropes with a wide range of sizes; consistent with this hypothesis, flux rope signatures are observed down to the smallest scales resolved by the diagnostics. Finally, a qualitative, 3-D, two-fluid model is proposed to explain the observed disruptions. Many of the features observed in MRX including current disruptions [6], flux ropes [7], and electromagnetic fluctuations [8] have analogues in space observations. Thus, further detailed comparisons may enhance our understanding

  15. Nuclear magnetic resonance gyroscope

    SciTech Connect

    Grover, B.C.

    1984-02-07

    A nuclear magnetic resonance gyro using two nuclear magnetic resonance gases, preferably xenon 129 and xenon 131, together with two alkaline metal vapors, preferably rubidium, potassium or cesium, one of the two alkaline metal vapors being pumped by light which has the wavelength of that alkaline metal vapor, and the other alkaline vapor being illuminated by light which has the wavelength of that other alkaline vapor.

  16. 3D conductive coupling for efficient generation of prominent Fano resonances in metamaterials

    NASA Astrophysics Data System (ADS)

    Liu, Zhiguang; Liu, Zhe; Li, Jiafang; Li, Wuxia; Li, Junjie; Gu, Changzhi; Li, Zhi-Yuan

    2016-06-01

    We demonstrate a 3D conductive coupling mechanism for the efficient generation of prominent and robust Fano resonances in 3D metamaterials (MMs) formed by integrating vertical U-shape split-ring resonators (SRRs) or vertical rectangular plates along a planar metallic hole array with extraordinary optical transmission (EOT). In such a configuration, intensified vertical E-field is induced along the metallic holes and naturally excites the electric resonances of the vertical structures, which form non-radiative “dark” modes. These 3D conductive “dark” modes strongly interfere with the “bright” resonance mode of the EOT structure, generating significant Fano resonances with both prominent destructive and constructive interferences. The demonstrated 3D conductive coupling mechanism is highly universal in that both 3D MMs with vertical SRRs and vertical plates exhibit the same prominent Fano resonances despite their dramatic structural difference, which is conceptually different from conventional capacitive and inductive coupling mechanisms that degraded drastically upon small structural deviations.

  17. Plasmon coupling of magnetic resonances in an asymmetric gold semishell

    NASA Astrophysics Data System (ADS)

    Ye, Jian; Kong, Yan; Liu, Cheng

    2016-05-01

    The generation of magnetic dipole resonances in metallic nanostructures is of great importance for constructing near-zero or even negative refractive index metamaterials. Commonly, planar two-dimensional (2D) split-ring resonators or relevant structures are basic elements of metamaterials. In this work, we introduce a three-dimensional (3D) asymmetric Au semishell composed of two nanocups with a face-to-face geometry and demonstrate two distinct magnetic resonances spontaneously in the visible-near infrared optical wavelength regime. These two magnetic resonances are from constructive and destructive hybridization of magnetic dipoles of individual nanocups in the asymmetric semishell. In contrast, complete cancellation of magnetic dipoles in the symmetric semishell leads to only a pronounced electric mode with near-zero magnetic dipole moment. These 3D asymmetric resonators provide new ways for engineering hybrid resonant modes and ultra-high near-field enhancement for the design of 3D metamaterials.

  18. Ce 5d and Fe 3d magnetic profiles in CeH2/Fe multilayers probed by XRMS

    NASA Astrophysics Data System (ADS)

    Jaouen, N.; Tonnerre, J. M.; Raoux, D.; Ortega, L.; Bontempi, E.; Münzenberg, M.; Felsch, W.; Suzuki, M.; Maruyama, H.; Dürr, H. A.; Dudzik, E.; van der Laan, G.

    The element and electronic shell specificities of X-ray resonant magnetic scattering have been used to investigate the magnetization of Ce 5d and Fe 3d states in [CeH2(19.6 Å)/Fe(25.4 Å)]*38 a multilayer. We show that the measurement of the magnetic contribution to the intensities reflected at low angles at the Ce L2 and Fe L2,3 edges allows us to investigate the profile of the Ce 5d and Fe 3d magnetic polarization. The Fe 3d polarization is found to be uniform across the Fe layer and the Ce 5d polarization appears to be restricted close to the interface with Fe.

  19. Three-dimensional two-fluid investigation of 3D-localized magnetic reconnection and its relation to whistler waves

    NASA Astrophysics Data System (ADS)

    Yoon, Young Dae; Bellan, Paul M.

    2016-10-01

    A full three-dimensional computer code was developed in order to simulate a 3D-localized magnetic reconnection. We assume an incompressible two-fluid regime where the ions are stationary, and electron inertia and Hall effects are present. We solve a single dimensionless differential equation for perturbed magnetic fields with arbitrary background fields. The code has successfully reproduced both experimental and analytic solutions to resonance and Gendrin mode whistler waves in a uniform background field. The code was then modified to model 3D-localized magnetic reconnection as a 3D-localized perturbation on a hyperbolic-tangent background field. Three-dimensional properties that are asymmetric in the out-of-plane direction have been observed. These properties pertained to magnetic field lines, electron currents and their convection. Helicity and energy have also been examined, as well as the addition of a guide field.

  20. Magnetic resonance imaging of the cervical spine: comparison of 2D T2-weighted turbo spin echo, 2D T2*weighted gradient-recalled echo and 3D T2-weighted variable flip-angle turbo spin echo sequences.

    PubMed

    Meindl, T; Wirth, S; Weckbach, S; Dietrich, O; Reiser, M; Schoenberg, S O

    2009-03-01

    To compare an isotropic three-dimensional (3D) high-resolution T2-weighted (w) MR sequence and its reformations with conventional sequences for imaging of the cervical spine. Fifteen volunteers were examined at 1.5 T using sagittal and axial 3D T2-w, sagittal and axial 2D T2w, and axial 2D T2*w MR sequences. Axial reformations of the sagittal 3D dataset were generated (3D MPR T2w). Signal-to-noise and image homogeneity were evaluated in a phantom and in vivo. Visibility of ten anatomical structures of the cervical spine was evaluated. Artifacts were assessed. For statistical analysis, Cohen's kappa, Wilcoxon matched pairs, and t-testing were utilized. There were no significant differences in homogeneity between the sequences. Sagittal 3D T2w enabled better delineation of nerve roots, neural foramina, and intraforaminal structures compared to sagittal 2D T2w. Axial 3D T2w and axial 3D MPR T2w resulted in superior visibility of most anatomical structures compared to axial 2D T2w and comparable results to 2D T2*w concerning the spinal cord, nerve roots, intraforaminal structures, and fat. Artifacts were most pronounced in axial 2D T2w and axial 3D T2w. Acquisition of a 3D T2w data set is feasible in the cervical spine with superior delineation of anatomical structures compared to 2D sequences.

  1. Effects of magnetic ripple on 3D equilibrium and alpha particle confinement in the European DEMO

    NASA Astrophysics Data System (ADS)

    Pfefferlé, D.; Cooper, W. A.; Fasoli, A.; Graves, J. P.

    2016-11-01

    An assessment of alpha particle confinement is performed in the European DEMO reference design. 3D MHD equilibria with nested flux-surfaces and single magnetic axis are obtained with the VMEC free-boundary code, thereby including the plasma response to the magnetic ripple created by the finite number of TF coils. Populations of fusion alphas that are consistent with the equilibrium profiles are evolved until slowing-down with the VENUS-LEVIS orbit code in the guiding-centre approximation. Fast ion losses through the last-closed flux-surface are numerically evaluated with two ripple models: (1) using the 3D equilibrium and (2) algebraically adding the non-axisymmetric ripple perturbation to the 2D equilibrium. By virtue of the small ripple field and its non-resonant nature, both models quantitatively agree. Differences are however noted in the toroidal location of particles losses on the last-closed flux-surface, which in the first case is 3D and in the second not. Superbanana transport, i.e. ripple-well trapping and separatrix crossing, is expected to be the dominant loss mechanism, the strongest effect on alphas being between 100-200 KeV. Above this, stochastic ripple diffusion is responsible for a rather weak loss rate, as the stochastisation threshold is observed numerically to be higher than analytic estimates. The level of ripple in the current 18 TF coil design of the European DEMO is not found to be detrimental to fusion alpha confinement.

  2. Joint inversions of two VTEM surveys using quasi-3D TDEM and 3D magnetic inversion algorithms

    NASA Astrophysics Data System (ADS)

    Kaminski, Vlad; Di Massa, Domenico; Viezzoli, Andrea

    2016-05-01

    In the current paper, we present results of a joint quasi-three-dimensional (quasi-3D) inversion of two versatile time domain electromagnetic (VTEM) datasets, as well as a joint 3D inversion of associated aeromagnetic datasets, from two surveys flown six years apart from one another (2007 and 2013) over a volcanogenic massive sulphide gold (VMS-Au) prospect in northern Ontario, Canada. The time domain electromagnetic (TDEM) data were inverted jointly using the spatially constrained inversion (SCI) approach. In order to increase the coherency in the model space, a calibration parameter was added. This was followed by a joint inversion of the total magnetic intensity (TMI) data extracted from the two surveys. The results of the inversions have been studied and matched with the known geology, adding some new valuable information to the ongoing mineral exploration initiative.

  3. Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in Dementias

    PubMed Central

    Hsu, Yuan-Yu; Du, An-Tao; Schuff, Norbert; Weiner, Michael W.

    2007-01-01

    This article reviews recent studies of magnetic resonance imaging and magnetic resonance spectroscopy in dementia, including Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, idiopathic Parkinson's disease, Huntington's disease, and vascular dementia. Magnetic resonance imaging and magnetic resonance spectroscopy can detect structural alteration and biochemical abnormalities in the brain of demented subjects and may help in the differential diagnosis and early detection of affected individuals, monitoring disease progression, and evaluation of therapeutic effect. PMID:11563438

  4. Fast ion transport during applied 3D magnetic perturbations on DIII-D

    DOE PAGES

    Van Zeeland, Michael A.; Ferraro, N. M.; Grierson, Brian A.; ...

    2015-06-26

    In this paper, measurements show fast ion losses correlated with applied three-dimensional (3D) fields in a variety of plasmas ranging from L-mode to resonant magnetic perturbation (RMP) edge localized mode (ELM) suppressed H-mode discharges. In DIII-D L-mode discharges with a slowly rotatingmore » $n=2$ magnetic perturbation, scintillator detector loss signals synchronized with the applied fields are observed to decay within one poloidal transit time after beam turn-off indicating they arise predominantly from prompt loss orbits. Full orbit following using M3D-C1 calculations of the perturbed fields and kinetic profiles reproduce many features of the measured losses and points to the importance of the applied 3D field phase with respect to the beam injection location in determining the overall impact on prompt beam ion loss. Modeling of these results includes a self-consistent calculation of the 3D perturbed beam ion birth profiles and scrape-off-layer ionization, a factor found to be essential to reproducing the experimental measurements. Extension of the simulations to full slowing down timescales, including fueling and the effects of drag and pitch angle scattering, show the applied $n=3$ RMPs in ELM suppressed H-mode plasmas can induce a significant loss of energetic particles from the core. With the applied $n=3$ fields, up to 8.4% of the injected beam power is predicted to be lost, compared to 2.7% with axisymmetric fields only. These fast ions, originating from minor radii $$\\rho >0.7$$ , are predicted to be primarily passing particles lost to the divertor region, consistent with wide field-of-view infrared periscope measurements of wall heating in $n=3$ RMP ELM suppressed plasmas. Edge fast ion $${{\\text{D}}_{\\alpha}}$$ (FIDA) measurements also confirm a large change in edge fast ion profile due to the $n=3$ fields, where the effect was isolated by using short 50 ms RMP-off periods during which ELM suppression was maintained yet the fast ion profile

  5. Fast ion transport during applied 3D magnetic perturbations on DIII-D

    SciTech Connect

    Van Zeeland, Michael A.; Ferraro, N. M.; Grierson, Brian A.; Heidbrink, W. W.; Kramer, G. J.; Lasnier, C. J.; Pace, David C.; Allen, Steve L.; Chen, X.; Evans, T. E.; García-Muñoz, M.; Hanson, J. M.; Lanctot, M. J.; Lao, L. L.; Meyer, W. H.; Moyer, R. A.; Nazikian, R.; Orlov, D. M.; Paz-Soldan, C.; Wingen, A.

    2015-06-26

    In this paper, measurements show fast ion losses correlated with applied three-dimensional (3D) fields in a variety of plasmas ranging from L-mode to resonant magnetic perturbation (RMP) edge localized mode (ELM) suppressed H-mode discharges. In DIII-D L-mode discharges with a slowly rotating $n=2$ magnetic perturbation, scintillator detector loss signals synchronized with the applied fields are observed to decay within one poloidal transit time after beam turn-off indicating they arise predominantly from prompt loss orbits. Full orbit following using M3D-C1 calculations of the perturbed fields and kinetic profiles reproduce many features of the measured losses and points to the importance of the applied 3D field phase with respect to the beam injection location in determining the overall impact on prompt beam ion loss. Modeling of these results includes a self-consistent calculation of the 3D perturbed beam ion birth profiles and scrape-off-layer ionization, a factor found to be essential to reproducing the experimental measurements. Extension of the simulations to full slowing down timescales, including fueling and the effects of drag and pitch angle scattering, show the applied $n=3$ RMPs in ELM suppressed H-mode plasmas can induce a significant loss of energetic particles from the core. With the applied $n=3$ fields, up to 8.4% of the injected beam power is predicted to be lost, compared to 2.7% with axisymmetric fields only. These fast ions, originating from minor radii $\\rho >0.7$ , are predicted to be primarily passing particles lost to the divertor region, consistent with wide field-of-view infrared periscope measurements of wall heating in $n=3$ RMP ELM suppressed plasmas. Edge fast ion ${{\\text{D}}_{\\alpha}}$ (FIDA) measurements also confirm a large change in edge fast ion profile due to the $n=3$ fields, where the effect was isolated by using short 50 ms RMP-off periods during which ELM suppression was maintained yet the fast ion profile was allowed

  6. Functional Magnetic Resonance Imaging

    ERIC Educational Resources Information Center

    Voos, Avery; Pelphrey, Kevin

    2013-01-01

    Functional magnetic resonance imaging (fMRI), with its excellent spatial resolution and ability to visualize networks of neuroanatomical structures involved in complex information processing, has become the dominant technique for the study of brain function and its development. The accessibility of in-vivo pediatric brain-imaging techniques…

  7. Magnetic resonance imaging

    SciTech Connect

    Stark, D.D.; Bradley, W.G. Jr.

    1988-01-01

    The authors present a review of magnetic resonance imaging. Many topics are explored from instrumentation, spectroscopy, blood flow and sodium imaging to detailed clinical applications such as the differential diagnosis of multiple sclerosis or adrenal adenoma. The emphasis throughout is on descriptions of normal multiplanar anatomy and pathology as displayed by MRI.

  8. Single spin magnetic resonance.

    PubMed

    Wrachtrup, Jörg; Finkler, Amit

    2016-08-01

    Different approaches have improved the sensitivity of either electron or nuclear magnetic resonance to the single spin level. For optical detection it has essentially become routine to observe a single electron spin or nuclear spin. Typically, the systems in use are carefully designed to allow for single spin detection and manipulation, and of those systems, diamond spin defects rank very high, being so robust that they can be addressed, read out and coherently controlled even under ambient conditions and in a versatile set of nanostructures. This renders them as a new type of sensor, which has been shown to detect single electron and nuclear spins among other quantities like force, pressure and temperature. Adapting pulse sequences from classic NMR and EPR, and combined with high resolution optical microscopy, proximity to the target sample and nanoscale size, the diamond sensors have the potential to constitute a new class of magnetic resonance detectors with single spin sensitivity. As diamond sensors can be operated under ambient conditions, they offer potential application across a multitude of disciplines. Here we review the different existing techniques for magnetic resonance, with a focus on diamond defect spin sensors, showing their potential as versatile sensors for ultra-sensitive magnetic resonance with nanoscale spatial resolution.

  9. Magnetic Resonance Annual, 1985

    SciTech Connect

    Kressel, H.Y.

    1985-01-01

    The inaugural volume of Magnetic Resonance Annual includes reviews of MRI of the posterior fossa, cerebral neoplasms, and the cardiovascular and genitourinary systems. A chapter on contrast materials outlines the mechanisms of paramagnetic contrast enhancement and highlights several promising contrast agents.

  10. Single spin magnetic resonance

    NASA Astrophysics Data System (ADS)

    Wrachtrup, Jörg; Finkler, Amit

    2016-08-01

    Different approaches have improved the sensitivity of either electron or nuclear magnetic resonance to the single spin level. For optical detection it has essentially become routine to observe a single electron spin or nuclear spin. Typically, the systems in use are carefully designed to allow for single spin detection and manipulation, and of those systems, diamond spin defects rank very high, being so robust that they can be addressed, read out and coherently controlled even under ambient conditions and in a versatile set of nanostructures. This renders them as a new type of sensor, which has been shown to detect single electron and nuclear spins among other quantities like force, pressure and temperature. Adapting pulse sequences from classic NMR and EPR, and combined with high resolution optical microscopy, proximity to the target sample and nanoscale size, the diamond sensors have the potential to constitute a new class of magnetic resonance detectors with single spin sensitivity. As diamond sensors can be operated under ambient conditions, they offer potential application across a multitude of disciplines. Here we review the different existing techniques for magnetic resonance, with a focus on diamond defect spin sensors, showing their potential as versatile sensors for ultra-sensitive magnetic resonance with nanoscale spatial resolution.

  11. Magnetic reconnection in 3D magnetosphere models: magnetic separators and open flux production

    NASA Astrophysics Data System (ADS)

    Glocer, A.; Dorelli, J.; Toth, G.; Komar, C. M.; Cassak, P.

    2014-12-01

    There are multiple competing definitions of magnetic reconnection in 3D (e.g., Hesse and Schindler [1988], Lau and Finn [1990], and Boozer [2002]). In this work we focus on separator reconnection. A magnetic separator can be understood as the 3D analogue of a 2D x line with a guide field, and is defined by the line corresponding to the intersection of the separatrix surfaces associated with the magnetic nulls. A separator in the magnetosphere represents the intersection of four distinct magnetic topologies: solar wind, closed, open connected to the northern hemisphere, and open connected to the southern hemisphere. The integral of the parallel electric field along the separator defines the rate of open flux production, and is one measure of the reconnection rate. We present three methods for locating magnetic separators and apply them to 3D resistive MHD simulations of the Earth's magnetosphere using the BATS-R-US code. The techniques for finding separators and determining the reconnection rate are insensitive to IMF clock angle and can in principle be applied to any magnetospheric model. The present work examines cases of high and low resistivity, for two clock angles. We also examine the separator during Flux Transfer Events (FTEs) and Kelvin-Helmholtz instability.

  12. Resonant magnetic vortices

    SciTech Connect

    Decanini, Yves; Folacci, Antoine

    2003-04-01

    By using the complex angular momentum method, we provide a semiclassical analysis of electron scattering by a magnetic vortex of Aharonov-Bohm type. Regge poles of the S matrix are associated with surface waves orbiting around the vortex and supported by a magnetic field discontinuity. Rapid variations of sharp characteristic shapes can be observed on scattering cross sections. They correspond to quasibound states which are Breit-Wigner-type resonances associated with surface waves and which can be considered as quantum analogues of acoustic whispering-gallery modes. Such a resonant magnetic vortex could provide a different kind of artificial atom while the semiclassical approach developed here could be profitably extended in various areas of the physics of vortices.

  13. Optimization of a Hybrid Magnetic Bearing for a Magnetically Levitated Blood Pump via 3-D FEA

    PubMed Central

    Cheng, Shanbao; Olles, Mark W.; Burger, Aaron F.; Day, Steven W.

    2011-01-01

    In order to improve the performance of a magnetically levitated (maglev) axial flow blood pump, three-dimensional (3-D) finite element analysis (FEA) was used to optimize the design of a hybrid magnetic bearing (HMB). Radial, axial, and current stiffness of multiple design variations of the HMB were calculated using a 3-D FEA package and verified by experimental results. As compared with the original design, the optimized HMB had twice the axial stiffness with the resulting increase of negative radial stiffness partially compensated for by increased current stiffness. Accordingly, the performance of the maglev axial flow blood pump with the optimized HMBs was improved: the maximum pump speed was increased from 6000 rpm to 9000 rpm (50%). The radial, axial and current stiffness of the HMB was found to be linear at nominal operational position from both 3-D FEA and empirical measurements. Stiffness values determined by FEA and empirical measurements agreed well with one another. The magnetic flux density distribution and flux loop of the HMB were also visualized via 3-D FEA which confirms the designers’ initial assumption about the function of this HMB. PMID:22065892

  14. Optimization of a Hybrid Magnetic Bearing for a Magnetically Levitated Blood Pump via 3-D FEA.

    PubMed

    Cheng, Shanbao; Olles, Mark W; Burger, Aaron F; Day, Steven W

    2011-10-01

    In order to improve the performance of a magnetically levitated (maglev) axial flow blood pump, three-dimensional (3-D) finite element analysis (FEA) was used to optimize the design of a hybrid magnetic bearing (HMB). Radial, axial, and current stiffness of multiple design variations of the HMB were calculated using a 3-D FEA package and verified by experimental results. As compared with the original design, the optimized HMB had twice the axial stiffness with the resulting increase of negative radial stiffness partially compensated for by increased current stiffness. Accordingly, the performance of the maglev axial flow blood pump with the optimized HMBs was improved: the maximum pump speed was increased from 6000 rpm to 9000 rpm (50%). The radial, axial and current stiffness of the HMB was found to be linear at nominal operational position from both 3-D FEA and empirical measurements. Stiffness values determined by FEA and empirical measurements agreed well with one another. The magnetic flux density distribution and flux loop of the HMB were also visualized via 3-D FEA which confirms the designers' initial assumption about the function of this HMB.

  15. Effects of 3D Toroidally Asymmetric Magnetic Field on Tokamak Magnetic Surfaces

    NASA Astrophysics Data System (ADS)

    Lao, L. L.

    2005-10-01

    The effects of 3D error magnetic field on magnetic surfaces are investigated using the DIII-D internal coils (I-Coils). Slowly rotating n=1 traveling waves at 5 Hz and various amplitudes were applied to systematically perturb the edge surfaces by programming the I-Coil currents. The vertical separatrix location difference between EFIT magnetic reconstructions that assumes toroidal symmetry and Thomson scattering Te measurements responds in phase to the applied perturbed field. The oscillation amplitudes increase with the strength of the applied field but are much smaller than those expected from the applied field alone. The results indicate that plasma response is important. Various plasma response models based on results from the MHD codes MARS and GATO are being developed and compared to the experimental observations. To more accurately evaluate the effects of magnetic measurement errors, a new form of the magnetic uncertainty matrix is also being implemented into EFIT. Details will be presented.

  16. DIII-D Equilibrium Reconstructions with New 3D Magnetic Probes

    NASA Astrophysics Data System (ADS)

    Lao, Lang; Strait, E. J.; Ferraro, N. M.; Ferron, J. R.; King, J. D.; Lee, X.; Meneghini, O.; Turnbull, A. D.; Huang, Y.; Qian, J. G.; Wingen, A.

    2015-11-01

    DIII-D equilibrium reconstructions with the recently installed new 3D magnetic diagnostic are presented. In addition to providing information to allow more accurate 2D reconstructions, the new 3D probes also provide useful information to guide computation of 3D perturbed equilibria. A new more comprehensive magnetic compensation has been implemented. Algorithms are being developed to allow EFIT to reconstruct 3D perturbed equilibria making use of the new 3D probes and plasma responses from 3D MHD codes such as GATO and M3D-C1. To improve the computation efficiency, all inactive probes in one of the toroidal planes in EFIT have been replaced with new probes from other planes. Other 3D efforts include testing of 3D reconstructions using V3FIT and a new 3D variational moment equilibrium code VMOM3D. Other EFIT developments include a GPU EFIT version and new safety factor and MSE-LS constraints. The accuracy and limitation of the new probes for 3D reconstructions will be discussed. Supported by US DOE under DE-FC02-04ER54698 and DE-FG02-95ER54309.

  17. Contiguous 3 d and 4 f Magnetism: Strongly Correlated 3 d Electrons in YbFe2Al10

    NASA Astrophysics Data System (ADS)

    Khuntia, P.; Peratheepan, P.; Strydom, A. M.; Utsumi, Y.; Ko, K.-T.; Tsuei, K.-D.; Tjeng, L. H.; Steglich, F.; Baenitz, M.

    2014-11-01

    We present magnetization, specific heat, and Al 27 NMR investigations on YbFe2Al10 over a wide range in temperature and magnetic field. The magnetic susceptibility at low temperatures is strongly enhanced at weak magnetic fields, accompanied by a ln (T0/T ) divergence of the low-T specific heat coefficient in zero field, which indicates a ground state of correlated electrons. From our hard-x-ray photoemission spectroscopy study, the Yb valence at 50 K is evaluated to be 2.38. The system displays valence fluctuating behavior in the low to intermediate temperature range, whereas above 400 K, Yb3 + carries a full and stable moment, and Fe carries a moment of about 3.1 μB. The enhanced value of the Sommerfeld-Wilson ratio and the dynamic scaling of the spin-lattice relaxation rate divided by T [(1 /T1T ) 27 ] with static susceptibility suggests admixed ferromagnetic correlations. (1 /T1T ) 27 simultaneously tracks the valence fluctuations from the 4 f Yb ions in the high temperature range and field dependent antiferromagnetic correlations among partially Kondo screened Fe 3 d moments at low temperature; the latter evolve out of an Yb 4 f admixed conduction band.

  18. A 3D Current Loop Model of Magnetic Clouds

    NASA Astrophysics Data System (ADS)

    Chen, James

    1992-05-01

    A magnetohydrodynamic (MHD) model is developed to study magnetic clouds (Burlaga et al. 1981). In this model, magnetic clouds observed near 1 AU are treated as a consequence of eruptive solar current loops. It is shown that current loops intially in MHD equilibrium can be triggered to rise rapidly, propelling material of up to 10(16) g at up to ~ 1000 km s(-1) and dissipating ~ 10(32) erg of magnetic energy in tens of minutes. The initial rise profile is consistent with observed height-time profiles of erupting filaments (Kahler et al. 1988). Two triggering mechanisms for eruption are suggested: (1)subphotospheric energy storage and trigger and (2) in situ (coronal) energy storage and trigger. In the former, eruption occurs as a result of changes in the subphotospheric magnetic topology and subsequent relaxation to a new equilibrium. In the latter, the current loop can evolve to exceed a local maximum in the magnetic potential associated with the ambient magnetic fields. The former scenario leads to more energetic and longer-lasting eruption than the latter. Burlaga, L. F., Sittler, E., Mariani, F., and Schwenn, R. 1981, J. Geophys. Res., 86, 6673. Kahler, S. W., Moore, R. L., Kane, S. R., and Zirin, H. 1988, Ap. J., 328, 824.

  19. 3D stochastic joint inversion of gravity and magnetic data

    NASA Astrophysics Data System (ADS)

    Shamsipour, Pejman; Marcotte, Denis; Chouteau, Michel

    2012-04-01

    A novel stochastic joint inversion method based on cokriging is applied to estimate density and magnetic susceptibility distributions from gravity and total magnetic field data. The method fully integrates the physical relations between density-gravity, on one hand, and magnetic susceptibility-total magnetic field, on the other hand. As a consequence, when the data are considered noise-free, the responses from the inverted density and susceptibility data exactly reproduce the observed data. The required density and magnetic susceptibility auto- and cross covariance are assumed to follow a linear model of coregionalization (LCM). The parameters of the LCM are estimated from v-v plot fitting of the gravity and total magnetic experimental covariances. The model is tested on two synthetic cases and one real data set, the Perseverance mine (Quebec, Canada). Joint inversions are compared to separate inversions. The joint inversions better recover the known models in the synthetic cases. With the real data set, better definition and location of the mineralized lenses are achieved by joint inversion.

  20. A symmetric, triply interlaced 3-D anionic MOF that exhibits both magnetic order and SMM behaviour.

    PubMed

    Campo, J; Falvello, L R; Forcén-Vázquez, E; Sáenz de Pipaón, C; Palacio, F; Tomás, M

    2016-11-14

    A newly prepared 3-D polymer of cobalt citrate cubanes bridged by high-spin Co(ii) centres displays both single-molecule magnet (SMM) behaviour and magnetic ordering. Triple interpenetration of the 3-D diamondoid polymers yields a crystalline solid with channels that host cations and free water molecules, with the SMM behaviour of the Co4O4 cores preserved. The octahedrally coordinated Co(ii) bridges are implicated in the onset of magnetic order at an experimentally accessible temperature.

  1. A Magnetic Diagnostic Code for 3D Fusion Equilibria

    SciTech Connect

    Samuel A. Lazerson, S. Sakakibara and Y. Suzuki

    2013-03-12

    A synthetic magnetic diagnostics code for fusion equilibria is presented. This code calculates the response of various magnetic diagnostics to the equilibria produced by the VMEC and PIES codes. This allows for treatment of equilibria with both good nested flux surfaces and those with stochastic regions. DIAGNO v2.0 builds upon previous codes through the implementation of a virtual casing principle. The code is validated against a vacuum shot on the Large Helical Device (LHD) where the vertical field was ramped. As an exercise of the code, the diagnostic response for various equilibria are calculated on the LHD.

  2. Magnetic Resonance Safety

    PubMed Central

    Sammet, Steffen

    2016-01-01

    Magnetic Resonance Imaging (MRI) has a superior soft-tissue contrast compared to other radiological imaging modalities and its physiological and functional applications have led to a significant increase in MRI scans worldwide. A comprehensive MRI safety training to protect patients and other healthcare workers from potential bio-effects and risks of the magnetic fields in an MRI suite is therefore essential. The knowledge of the purpose of safety zones in an MRI suite as well as MRI appropriateness criteria is important for all healthcare professionals who will work in the MRI environment or refer patients for MRI scans. The purpose of this article is to give an overview of current magnetic resonance safety guidelines and discuss the safety risks of magnetic fields in an MRI suite including forces and torque of ferromagnetic objects, tissue heating, peripheral nerve stimulation and hearing damages. MRI safety and compatibility of implanted devices, MRI scans during pregnancy and the potential risks of MRI contrast agents will also be discussed and a comprehensive MRI safety training to avoid fatal accidents in an MRI suite will be presented. PMID:26940331

  3. Very Broad X(4260) and the Resonance Parameters of the ψ(3D) Vector Charmonium State

    NASA Astrophysics Data System (ADS)

    van Beveren, Eef; Rupp, George; Segovia, J.

    2010-09-01

    We argue that the X(4260) enhancement contains a wealth of information on 1-- cc¯ spectroscopy. We discuss the shape of the X(4260) observed in the Okubo-Zweig-Iizuka-forbidden process e+e-→π+π-J/ψ, in particular, at and near vector charmonium resonances as well as open-charm threshold enhancements. The resulting very broad X(4260) structure does not seem to classify itself as a 1-- cc¯ resonance, but its detailed shape allows us to identify new vector charmonium states with higher statistics than in open-charm decay. Here, we estimate the resonance parameters of the ψ(3D). Our approach also provides an explanation for the odd dip in the π+π-J/ψ data precisely at the ψ(4415) resonance.

  4. Very Broad X(4260) and the Resonance Parameters of the {psi}(3D) Vector Charmonium State

    SciTech Connect

    Beveren, Eef van; Rupp, George; Segovia, J.

    2010-09-03

    We argue that the X(4260) enhancement contains a wealth of information on 1{sup --} cc spectroscopy. We discuss the shape of the X(4260) observed in the Okubo-Zweig-Iizuka-forbidden process e{sup +}e{sup -}{yields}{pi}{sup +}{pi}{sup -}J/{psi}, in particular, at and near vector charmonium resonances as well as open-charm threshold enhancements. The resulting very broad X(4260) structure does not seem to classify itself as a 1{sup --} cc resonance, but its detailed shape allows us to identify new vector charmonium states with higher statistics than in open-charm decay. Here, we estimate the resonance parameters of the {psi}(3D). Our approach also provides an explanation for the odd dip in the {pi}{sup +}{pi}{sup -}J/{psi} data precisely at the {psi}(4415) resonance.

  5. Cavity- and waveguide-resonators in electron paramagnetic resonance, nuclear magnetic resonance, and magnetic resonance imaging.

    PubMed

    Webb, Andrew

    2014-11-01

    Cavity resonators are widely used in electron paramagnetic resonance, very high field magnetic resonance microimaging and also in high field human imaging. The basic principles and designs of different forms of cavity resonators including rectangular, cylindrical, re-entrant, cavity magnetrons, toroidal cavities and dielectric resonators are reviewed. Applications in EPR and MRI are summarized, and finally the topic of traveling wave MRI using the magnet bore as a waveguide is discussed.

  6. Three-Dimensional Magnetic Resonance Imaging of Velopharyngeal Structures

    ERIC Educational Resources Information Center

    Bae, Youkyung; Kuehn, David P.; Sutton, Bradley P.; Conway, Charles A.; Perry, Jamie L.

    2011-01-01

    Purpose: To report the feasibility of using a 3-dimensional (3D) magnetic resonance imaging (MRI) protocol for examining velopharyngeal structures. Using collected 3D MRI data, the authors investigated the effect of sex on the midsagittal velopharyngeal structures and the levator veli palatini (levator) muscle configurations. Method: Ten Caucasian…

  7. Magnetic Resonance Facility (Fact Sheet)

    SciTech Connect

    Not Available

    2012-03-01

    This fact sheet provides information about Magnetic Resonance Facility capabilities and applications at NREL's National Bioenergy Center. Liquid and solid-state analysis capability for a variety of biomass, photovoltaic, and materials characterization applications across NREL. NREL scientists analyze solid and liquid samples on three nuclear magnetic resonance (NMR) spectrometers as well as an electron paramagnetic resonance (EPR) spectrometer.

  8. Nuclear Magnetic Resonance Gyroscope

    NASA Astrophysics Data System (ADS)

    Bulatowicz, Michael; Griffith, Robert; Larsen, Michael

    2014-03-01

    The navigation grade micro Nuclear Magnetic Resonance Gyroscope (micro-NMRG) being developed by the Northrop Grumman Corporation (NGC) has concluded the fourth and final phase of the DARPA Navigation Grade Integrated Micro Gyro (NGIMG) program. Traditional MEMS gyros utilize springs as an inherent part of the sensing mechanism, leading to bias and scale factor sensitivity to acceleration and vibration. As a result, they have not met performance expectations in real world environments and to date have been limited to tactical grade applications. The Nuclear Magnetic Resonance Gyroscope (NMRG) utilizes the fixed precession rate of a nuclear spin in a constant magnetic field as an inertial reference for determining rotation. The nuclear spin precession rate sensitivity to acceleration and vibration is negligible for most applications. Therefore, the application of new micro and batch fabrication methods to NMRG technology holds great promise for navigation grade performance in a low cost and compact gyro. This poster will describe the history, operational principles, design, and demonstrated performance of the NMRG including an overview of the NGC designs developed and demonstrated in the DARPA gyro development program.

  9. Nuclear Magnetic Resonance Gyroscope

    NASA Astrophysics Data System (ADS)

    Bulatowicz, Michael; Clark, Philip; Griffith, Robert; Larsen, Michael; Mirijanian, James

    2012-06-01

    The navigation grade micro Nuclear Magnetic Resonance Gyroscope (micro-NMRG) being developed by the Northrop Grumman Corporation is concluding the fourth and final phase of the DARPA Navigation Grade Integrated Micro Gyro (NGIMG) program. Traditional MEMS gyros utilize springs as an inherent part of the sensing mechanism, leading to bias and scale factor sensitivity to acceleration and vibration. As a result, they have not met performance expectations in real world environments and to date have been limited to tactical grade applications. The Nuclear Magnetic Resonance Gyroscope (NMRG) utilizes the fixed precession rate of a nuclear spin in a constant magnetic field as an inertial reference for determining rotation. The nuclear spin precession rate sensitivity to acceleration and vibration is negligible for most applications. Therefore, the application of new micro and batch fabrication methods to NMRG technology holds great promise for navigation grade performance in a low cost and compact gyro. This poster will describe the history, operational principles, and design basics of the NMRG including an overview of the NSD designs developed and demonstrated in the DARPA gyro development program. General performance results from phases 3 and 4 will also be presented.

  10. Nuclear Magnetic Resonance Gyroscope

    NASA Astrophysics Data System (ADS)

    Larsen, Michael; Griffith, Robert; Bulatowicz, Michael

    2014-03-01

    The navigation grade micro Nuclear Magnetic Resonance Gyroscope (micro-NMRG) being developed by the Northrop Grumman Corporation (NGC) has concluded the fourth and final phase of the DARPA Navigation Grade Integrated Micro Gyro (NGIMG) program. Traditional MEMS gyros utilize springs as an inherent part of the sensing mechanism, leading to bias and scale factor sensitivity to acceleration and vibration. As a result, they have not met performance expectations in real world environments and to date have been limited to tactical grade applications. The Nuclear Magnetic Resonance Gyroscope (NMRG) utilizes the fixed precession rate of a nuclear spin in a constant magnetic field as an inertial reference for determining rotation. The nuclear spin precession rate sensitivity to acceleration and vibration is negligible for most applications. Therefore, the application of new micro and batch fabrication methods to NMRG technology holds great promise for navigation grade performance in a low cost and compact gyro. This presentation will describe the operational principles, design basics, and demonstrated performance of the NMRG including an overview of the NGC designs developed and demonstrated in the DARPA gyro development program.

  11. Direct-write 3D printing of NdFeB bonded magnets

    DOE PAGES

    Compton, Brett Gibson; Kemp, James William; Novikov, Timofei V.; ...

    2016-08-17

    We report a method to fabricate Nd-Fe-B bonded magnets of complex shape via extrusion-based additive manufacturing (AM), also known as 3D-printing. We have successfully formulated a 3D-printable epoxy-based ink for direct-write AM with anisotropic MQA NdFeB magnet particles that can be deposited at room temperature. The new feedstocks contain up to 40 vol.% MQA anisotropic Nd-Fe-B magnet particles, and they are shown to remain uniformly dispersed in the thermoset matrix throughout the deposition process. Ring, bar, and horseshoe-type 3D magnet structures were printed and cured in air at 100°C without degrading the magnetic properties. Lastly, this study provides a newmore » pathway for fabricating Nd-Fe-B bonded magnets with complex geometry at low temperature, and presents new opportunities for fabricating multifunctional hybrid structures and devices.« less

  12. Direct-write 3D printing of NdFeB bonded magnets

    SciTech Connect

    Compton, Brett Gibson; Kemp, James William; Novikov, Timofei V.; Pack, Robert Cody; Nlebedim, Cajetan I.; Duty, Chad Edward; Rios, Orlando; Paranthaman, M. Parans

    2016-08-17

    We report a method to fabricate Nd-Fe-B bonded magnets of complex shape via extrusion-based additive manufacturing (AM), also known as 3D-printing. We have successfully formulated a 3D-printable epoxy-based ink for direct-write AM with anisotropic MQA NdFeB magnet particles that can be deposited at room temperature. The new feedstocks contain up to 40 vol.% MQA anisotropic Nd-Fe-B magnet particles, and they are shown to remain uniformly dispersed in the thermoset matrix throughout the deposition process. Ring, bar, and horseshoe-type 3D magnet structures were printed and cured in air at 100°C without degrading the magnetic properties. Lastly, this study provides a new pathway for fabricating Nd-Fe-B bonded magnets with complex geometry at low temperature, and presents new opportunities for fabricating multifunctional hybrid structures and devices.

  13. Statistical Flux Tube Properties of 3D Magnetic Carpet Fields

    NASA Astrophysics Data System (ADS)

    Close, R. M.; Parnell, C. E.; Mackay, D. H.; Priest, E. R.

    2003-02-01

    The quiet-Sun photosphere consists of numerous magnetic flux fragments of both polarities that evolve with granular and supergranular flow fields. These concentrations give rise to a web of intermingled magnetic flux tubes which characterise the coronal magnetic field. Here, the nature of these flux tubes is studied. The photosphere is taken to be the source plane and each photospheric fragment is represented by a series of point sources. By analysing the potential field produced by these sources, it is found that the distribution of flux tube lengths obtained by (i) integrating forward from positive sources and (ii) tracing back from negative sources is highly dependent on the total flux imbalance within the region of interest. It is established that the relation between the footpoint separation of a flux tube and its height cannot be assumed to be linear. Where there is a significant imbalance of flux within a region, it is found that fragments of the dominant polarity will have noticeably more connections, on average, than the minority polarity fragments. Despite this difference, the flux from a single fragment of either polarity is typically divided such that (i) 60-70% connects to one opposite-polarity fragment, (ii) 25-30% goes to a further 1 to 2 opposite-polarity fragments, and (iii) any remaining flux may connect to as many as another 50 or more other opposite-polarity fragments. This is true regardless of any flux imbalance within the region. It is found that fragments connect preferentially to their nearest neighbours, with, on average, around 60-70% of flux closing down within 10 Mm of a typical fragment. Only 50% of the flux in a quiet region extends higher than 2.5 Mm above the solar surface and 5-10% extends higher than 25 Mm. The fragments that contribute to the field above this height cover a range of sizes, with even the smallest of fragments contributing to the field at heights of over 50 Mm.

  14. Imaging solar coronal magnetic structures in 3D

    NASA Astrophysics Data System (ADS)

    Cartledge, N. P.

    The study of solar coronal structures and, in particular prominences, is a key part of understanding the highly complex physical mechanisms occurring in the Sun's atmosphere. Solar prominences are important in their own right and some of the most puzzling questions in solar theory have arisen through their study. For example, how do they form and how is their mass continuously replenished? How can the magnetic field provide their continuous support against gravity over time periods of several months? How can such cool, dense material exist in thermal equilibrium in the surrounding coronal environment? Why do they erupt? A study of their structure and that of the surrounding medium is important in determining the nature of the coronal plasma and magnetic field. Also, prominences are closely associated with other key phenomena such as coronal mass ejections and eruptive solar flares which occur as a prominence loses equilibrium and rises from the solar surface. Our current understanding of these fascinating structures is extremely limited and we know very little about their basic global structure. In fact, recent prominence observations have caused our basic paradigms to be challenged (Priest, 1996) and so we must set up new models in order to gain even a fundamental understanding. Prominences are highly nonlinear, three-dimensional structures. Large feet (or barbs) reach out from the main body of a prominence and reach down to the photosphere where the dense material continuously drains away. These provide a real clue to the three-dimensional nature of the coronal field and its relation to the photospheric field. It is important, therefore, to make stereographic observations of prominences in order to gain a basic understanding of their essentially three-dimensional nature and attempt to formulate new paradigms for their structure and evolution. There is no doubt that the study of prominences in three dimensions is a crucial exercise if we are to develop a better

  15. Online reconstruction of 3D magnetic particle imaging data

    NASA Astrophysics Data System (ADS)

    Knopp, T.; Hofmann, M.

    2016-06-01

    Magnetic particle imaging is a quantitative functional imaging technique that allows imaging of the spatial distribution of super-paramagnetic iron oxide particles at high temporal resolution. The raw data acquisition can be performed at frame rates of more than 40 volumes s-1. However, to date image reconstruction is performed in an offline step and thus no direct feedback is available during the experiment. Considering potential interventional applications such direct feedback would be mandatory. In this work, an online reconstruction framework is implemented that allows direct visualization of the particle distribution on the screen of the acquisition computer with a latency of about 2 s. The reconstruction process is adaptive and performs block-averaging in order to optimize the signal quality for a given amount of reconstruction time.

  16. 3-D explosions: a meditation on rotation (and magnetic fields)

    NASA Astrophysics Data System (ADS)

    Wheeler, J. C.

    This is the text of an introduction to a workshop on asymmetric explosions held in Austin in June, 2003. The great progress in supernova research over thirty-odd years is briefly reviewed. The context in which the meeting was called is then summarized. The theoretical success of the intrinsically multidimensional delayed detonation paradigm in explaining the nature of Type Ia supernovae coupled with new techniques of observations in the near IR and with spectropolarimetry promise great advances in understanding binary progenitors, the explosion physics, and the ever more accurate application to cosmology. Spectropolarimetry has also revealed the strongly asymmetric nature of core collapse and given valuable perspectives on the supernova - gamma-ray burst connection. The capability of the magneto-rotational instability to rapidly create strong toroidal magnetic fields in the core collapse ambiance is outlined. This physics may be the precursor to driving MHD jets that play a role in asymmetric supernovae. Welcome to the brave new world of three-dimensional explosions!

  17. nuclear magnetic resonance gyroscope

    SciTech Connect

    Karwacki, F. A.; Griffin, J.

    1985-04-02

    A nuclear magnetic resonance gyroscope which derives angular rotation thereof from the phases of precessing nuclear moments utilizes a single-resonance cell situated in the center of a uniform DC magnetic field. The field is generated by current flow through a circular array of coils between parallel plates. It also utilizes a pump and read-out beam and associated electronics for signal processing and control. Encapsulated in the cell for sensing rotation are odd isotopes of Mercury Hg/sup 199/ and Hg/sup 201/. Unpolarized intensity modulated light from a pump lamp is directed by lenses to a linear polarizer, quarter wave plate combination producing circularly polarized light. The circularly polarized light is reflected by a mirror to the cell transverse to the field for optical pumping of the isotopes. Unpolarized light from a readout lamp is directed by lenses to another linear polarizer. The linearly polarized light is reflected by another mirror to the cell transverse to the field and orthogonal to the pump lamp light. The linear light after transversing the cell strikes an analyzer where it is converted to an intensity-modulated light. The modulated light is detected by a photodiode processed and utilized as feedback to control the field and pump lamp excitation and readout of angular displacement.

  18. Partially orthogonal resonators for magnetic resonance imaging

    PubMed Central

    Chacon-Caldera, Jorge; Malzacher, Matthias; Schad, Lothar R.

    2017-01-01

    Resonators for signal reception in magnetic resonance are traditionally planar to restrict coil material and avoid coil losses. Here, we present a novel concept to model resonators partially in a plane with maximum sensitivity to the magnetic resonance signal and partially in an orthogonal plane with reduced signal sensitivity. Thus, properties of individual elements in coil arrays can be modified to optimize physical planar space and increase the sensitivity of the overall array. A particular case of the concept is implemented to decrease H-field destructive interferences in planar concentric in-phase arrays. An increase in signal to noise ratio of approximately 20% was achieved with two resonators placed over approximately the same planar area compared to common approaches at a target depth of 10 cm at 3 Tesla. Improved parallel imaging performance of this configuration is also demonstrated. The concept can be further used to increase coil density. PMID:28186135

  19. Partially orthogonal resonators for magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Chacon-Caldera, Jorge; Malzacher, Matthias; Schad, Lothar R.

    2017-02-01

    Resonators for signal reception in magnetic resonance are traditionally planar to restrict coil material and avoid coil losses. Here, we present a novel concept to model resonators partially in a plane with maximum sensitivity to the magnetic resonance signal and partially in an orthogonal plane with reduced signal sensitivity. Thus, properties of individual elements in coil arrays can be modified to optimize physical planar space and increase the sensitivity of the overall array. A particular case of the concept is implemented to decrease H-field destructive interferences in planar concentric in-phase arrays. An increase in signal to noise ratio of approximately 20% was achieved with two resonators placed over approximately the same planar area compared to common approaches at a target depth of 10 cm at 3 Tesla. Improved parallel imaging performance of this configuration is also demonstrated. The concept can be further used to increase coil density.

  20. Fabrication of capacitive acoustic resonators combining 3D printing and 2D inkjet printing techniques.

    PubMed

    Haque, Rubaiyet Iftekharul; Ogam, Erick; Loussert, Christophe; Benaben, Patrick; Boddaert, Xavier

    2015-10-14

    A capacitive acoustic resonator developed by combining three-dimensional (3D) printing and two-dimensional (2D) printed electronics technique is described. During this work, a patterned bottom structure with rigid backplate and cavity is fabricated directly by a 3D printing method, and then a direct write inkjet printing technique has been employed to print a silver conductive layer. A novel approach has been used to fabricate a diaphragm for the acoustic sensor as well, where the conductive layer is inkjet-printed on a pre-stressed thin organic film. After assembly, the resulting structure contains an electrically conductive diaphragm positioned at a distance from a fixed bottom electrode separated by a spacer. Measurements confirm that the transducer acts as capacitor. The deflection of the diaphragm in response to the incident acoustic single was observed by a laser Doppler vibrometer and the corresponding change of capacitance has been calculated, which is then compared with the numerical result. Observation confirms that the device performs as a resonator and provides adequate sensitivity and selectivity at its resonance frequency.

  1. Fabrication of Capacitive Acoustic Resonators Combining 3D Printing and 2D Inkjet Printing Techniques

    PubMed Central

    Haque, Rubaiyet Iftekharul; Ogam, Erick; Loussert, Christophe; Benaben, Patrick; Boddaert, Xavier

    2015-01-01

    A capacitive acoustic resonator developed by combining three-dimensional (3D) printing and two-dimensional (2D) printed electronics technique is described. During this work, a patterned bottom structure with rigid backplate and cavity is fabricated directly by a 3D printing method, and then a direct write inkjet printing technique has been employed to print a silver conductive layer. A novel approach has been used to fabricate a diaphragm for the acoustic sensor as well, where the conductive layer is inkjet-printed on a pre-stressed thin organic film. After assembly, the resulting structure contains an electrically conductive diaphragm positioned at a distance from a fixed bottom electrode separated by a spacer. Measurements confirm that the transducer acts as capacitor. The deflection of the diaphragm in response to the incident acoustic single was observed by a laser Doppler vibrometer and the corresponding change of capacitance has been calculated, which is then compared with the numerical result. Observation confirms that the device performs as a resonator and provides adequate sensitivity and selectivity at its resonance frequency. PMID:26473878

  2. On the magnetotransport of 3D systems in quantizing magnetic field

    NASA Astrophysics Data System (ADS)

    Cheremisin, M. V.

    2014-12-01

    The resistivity components of 3D electron gas placed in quantizing magnetic field are calculated taking into account the correction caused by combined action of the Peltier and Seebeck thermoelectric effects. The longitudinal, transverse and the Hall magnetoresistivities exhibit familiar 1/B-period oscillations being universal functions of magnetic field and temperature.

  3. Single cell detection using 3D magnetic rolled-up structures.

    PubMed

    Ger, Tzong-Rong; Huang, Hao-Ting; Huang, Chen-Yu; Lai, Mei-Feng

    2013-11-07

    A 3D rolled-up structure made of a SiO2 layer and a fishbone-like magnetic thin film was proposed here as a biosensor. The magnetoresistance (MR) measurement results of the sensor suggest that the presence of the stray field, which is induced by the magnetic nanoparticles, significantly increased the switching field. Comparing the performance of the 2D sensor and 3D sensor designed in this study, the response in switching field variation was 12.14% in the 2D sensor and 62.55% in the 3D sensor. The response in MR ratio variation was 4.55% in the 2D sensor and 82.32% in the 3D sensor. In addition, the design of the 3D sensor structure also helped to attract and trap a single magnetic cell due to its stronger stray field compared with the 2D structure. The 3D magnetic biosensor designed here can provide important information for future biochip research and applications.

  4. Lithologic identification & mapping test based on 3D inversion of magnetic and gravity

    NASA Astrophysics Data System (ADS)

    Yan, Jiayong; Lv, Qingtian; Qi, Guang; Zhao, Jinhua; Zhang, Yongqian

    2016-04-01

    Though lithologic identification & mapping to achieve ore concentration district transparent within 5km depth is the main way to realize deep fine structures study, to explore deep mineral resources and to reveal metallogenic regularity of large-scale ore district . Owing to the wide covered area, high sampling density and mature three-dimensional inversion algorithm of gravity and magnetic data, so gravity and magnetic inversion become the most likely way to achieve three-dimensional lithologic mapping at the present stage. In this paper, we take Lu-zong(Lujiang county to Zongyang county in Anhui province ,east China) ore district as a case, we proposed lithologic mapping flow based 3D inversion of gravity magnetic and then carry out the lithologic mapping test. Lithologic identification & mapping flow is as follows: 1. Analysis relations between lithology and density and magnetic susceptibility by cross plot. 2.Extracting appropriate residual anomalies from high-precision Bourger gravity and aeromagnetic. 3.Use same mesh, do 3D magnetic and gravity inversion respectively under prior information constrained, and then invert susceptibility and density 3D model. 4. According setp1, construct logical topology operations between density 3D model and susceptibility. 5.Use the logical operations, identify lithogies cell by cell in 3D mesh, and then get 3D lithological model. According this flow, we obtained three-dimensional distribution of five main type lithologies in the Lu-Zong ore district within 5km depth. The result of lithologic mapping not only showed that the shallow characteristics and surface geological mapping are basically Coincide,more importantly ,it reveals the deeper lithologic changes.The lithlogical model make up the insufficient of surface geological mapping. The lithologic mapping test results in Lu-Zong ore concentration district showed that lithological mapping using 3D inversion of gravity and magnetic is a effective method to reveal the

  5. 3D-xy critical properties of YBa2Cu4O8 and magnetic-field-induced 3D to 1D crossover

    NASA Astrophysics Data System (ADS)

    Weyeneth, S.; Schneider, T.; Bukowski, Z.; Karpinski, J.; Keller, H.

    2008-08-01

    We present reversible magnetization data of a YBa2Cu4O8 single crystal and analyze the evidence for 3D-xy critical behavior and a magnetic-field-induced 3D to 1D crossover. Remarkable consistency with these phenomena is observed in agreement with a magnetic-field-induced finite size effect, whereupon the correlation length transverse to the applied magnetic field cannot grow beyond the limiting magnetic length scale LH = (Φ0/(aH))1/2. By applying the appropriate scaling form we obtain the zero-field critical temperature, the 3D to 1D crossover, the vortex melting line and the universal ratios of the related scaling variables. Accordingly there is no continuous phase transition in the (H,T) plane along the Hc2 lines as predicted by the mean-field treatment.

  6. 3D Magnetic Induction Maps of Nanoscale Materials Revealed by Electron Holographic Tomography

    PubMed Central

    2015-01-01

    The investigation of three-dimensional (3D) ferromagnetic nanoscale materials constitutes one of the key research areas of the current magnetism roadmap and carries great potential to impact areas such as data storage, sensing, and biomagnetism. The properties of such nanostructures are closely connected with their 3D magnetic nanostructure, making their determination highly valuable. Up to now, quantitative 3D maps providing both the internal magnetic and electric configuration of the same specimen with high spatial resolution are missing. Here, we demonstrate the quantitative 3D reconstruction of the dominant axial component of the magnetic induction and electrostatic potential within a cobalt nanowire (NW) of 100 nm in diameter with spatial resolution below 10 nm by applying electron holographic tomography. The tomogram was obtained using a dedicated TEM sample holder for acquisition, in combination with advanced alignment and tomographic reconstruction routines. The powerful approach presented here is widely applicable to a broad range of 3D magnetic nanostructures and may trigger the progress of novel spintronic nonplanar nanodevices. PMID:27182110

  7. Nuclear Magnetic Resonance Gyroscope

    NASA Astrophysics Data System (ADS)

    Larsen, Michael; Bulatowicz, Michael; Clark, Philip; Griffith, Robert; Mirijanian, James; Pavell, James

    2015-05-01

    The Nuclear Magnetic Resonance Gyroscope (NMRG) is being developed by the Northrop Grumman Corporation (NGC). Cold and hot atom interferometer based gyroscopes have suffered from Size, Weight, and Power (SWaP) challenges and limits in bandwidth, scale factor stability, dead time, high rotation rate, vibration, and acceleration. NMRG utilizes the fixed precession rate of a nuclear spin in a constant magnetic field as a reference for determining rotation, providing continuous measurement, high bandwidth, stable scale factor, high rotation rate measurement, and low sensitivity to vibration and acceleration in a low SWaP package. The sensitivity to vibration has been partially tested and demonstrates no measured sensitivity within error bars. Real time closed loop implementation of the sensor significantly decreases environmental and systematic sensitivities and supports a compact and low power digital signal processing and control system. Therefore, the NMRG technology holds great promise for navigation grade performance in a low cost SWaP package. The poster will describe the history, operation, and design of the NMRG. General performance results will also be presented along with recent vibration test results.

  8. Magnetic Dissipation in Asymmetric Strong Guide 3D Simulations: Examples of Magnetic Diffusion and Reconnection

    NASA Astrophysics Data System (ADS)

    Scudder, J. D.; Karimabadi, H.; Daughton, W. S.

    2013-12-01

    Interpretations of 2D simulations of magnetic reconnection are greatly simplified by using the flux function, usually the out of plane component of the vector potential. This theoretical device is no longer available when simulations are analyzed in 3-D. We illustrate the results of determining the locale rates of flux slippage in simulations by a technique based on Maxwell's equations. The technique recovers the usual results obtained for the flux function in 2D simulations, but remains viable in 3D simulations where there is no flux function. The method has also been successfully tested for full PIC simulations where reconnection is geometrically forbiddden. While such layers possess measurable flux slippages (diffusion) their level is not as strong as recorded in known 2D PIC reconnection sites using the same methodology. This approach will be used to explore the spatial incidence and strength of flux slippages across a 3D, asymmetric, strong guide field run discussed previously in the literature. Regions of diffusive behavior are illustrated where LHDI has been previously identified out on the separatrices, while much stronger flux slippages, typical of the X-regions of 2D simulations, are shown to occur elsewhere throughout the simulation. These results suggest that reconnection requires sufficiently vigorous flux slippage to be self sustaining, while non-zero flux slippage can and does occur without being at the reconnection site. A cross check of this approach is provided by the mixing ratio of tagged simulation particles of known spatial origin discussed by Daughton et al., 2013 (this meeting); they provide an integral measure of flux slippage up to the present point in the simulation. We will discuss the correlations between our Maxwell based flux slippage rates and the inferred rates of change of this mixing ratio (as recorded in the local fluid frame).

  9. Analysis and measurement of the 3D magnetic field in a rotating magnetic field driven FRC

    NASA Astrophysics Data System (ADS)

    Velas, K. M.; Milroy, R. D.

    2012-10-01

    A translatable three-axis probe was installed on TCSU shortly before its shutdown. The probe has 90 windings that simultaneously measure Br, Bθ, and Bz at 30 radial positions. Positioning the probe at multiple axial positions and taking multiple repeatable shots allows for a full r-z map of the magnetic field. Probe measurements are used to calculate the end-shorting torque and the rotating magnetic field (RMF) torque. The torque applied to the plasma is the RMF torque reduced by the shorting torque. An estimate of the plasma resistivity is made based on the steady state balance between the applied torque and the resistive torque. The steady state data from applying a 10 kHz low pass filter used in conjunction with data at the RMF frequency yields a map of the full 3D rotating field structure. Data from even- and odd-parity experiments will be presented. The NIMROD code has been adapted to simulate the TCSU experiment using boundary conditions adjusted to match both even- and odd-parity experimental conditions. A comparison of the n=0 components of the calculated fields to the 3-axis probe measurements shows agreement in the magnetic field structure of the FRC as well as in the jet region.

  10. Experimental Studies on the 3D Macro- and Microphysics of Magnetic Reconnection

    NASA Astrophysics Data System (ADS)

    Jara-Almonte, J.; Ji, H.; Yamada, M.; Yoo, J.; Fox, W. R., II

    2015-12-01

    Magnetic reconnection has been extensively studied in 2D geometries for many decades and considerable progress has been made in understating 2D reconnection physics, yet in real plasmas reconnection is fundamentally 3D in nature. Only recently has it become possible to study 3D reconnection using simulations, however some initial results have suggested that the inclusion of 3D effects does not strongly affect the basic properties of reconnection (e.g. reconnection rate or particle acceleration). Yet on the other hand, previous experiments, without direct 3D measurements, have implied that 3D effects could be important even in a quasi-2D system. Here we experimentally study both the (1) macro- and (2) microphysics of 3D reconnection in order to directly test the importance of 3D effects in a quasi-2D experiment. Using fully simultaneous 3D measurements, it is shown that during highly driven reconnection the macroscopic structure of the current sheet can become strongly 3D despite an essentially 2D upstream region. The correlation length along the current sheet is measured to be far shorter than suggested by kinetic simulations. Results from new experiments with stronger reconnection drive and diagnostics designed to estimate the 3D reconnection rate will be discussed. With regards to (2), the 3D microphysics, new diagnostics capable of measuring fluctuations at frequencies up to the electron cyclotron frequency (~ 300 MHz) have been developed and have identified the presence of very high frequency waves (~ 100 MHz) during asymmetric reconnection, localized to the low-density side. The detailed properties of these waves, including the measured power spectra and dispersion relation, will be discussed and compared with both previous satellite observations of high-frequency waves as well as with theoretical predictions on the generation of whistler waves during reconnection.

  11. Tuning the electronic and magnetic properties of borophene by 3d transition-metal atom adsorption

    NASA Astrophysics Data System (ADS)

    Li, J. Y.; Lv, H. Y.; Lu, W. J.; Shao, D. F.; Xiao, R. C.; Sun, Y. P.

    2016-12-01

    The electronic and magnetic properties of borophene functionalized by 3d transition metal (TM) atom adsorption are investigated by using first-principles calculations. The results show that the 3d TM atoms can be adsorbed on borophene with high binding energies ranging between 5.9 and 8.3 eV. Interestingly, the originally nonmagnetic borophene tends to be ferromagnetic when Ti, V, Cr, Mn, and Fe atoms are adsorbed, and the magnetic moments are dominated by the TM atoms. The origin of the ferromagnetism is discussed based on the Stoner criterion. Our results indicate that the magnetic properties of borophene can be effectively tuned through the adsorption of 3d TM atoms, which could have promising applications in spintronics and nanoelectronics.

  12. Multilevel-3D bit patterned magnetic media with 8 signal levels per nanocolumn.

    PubMed

    Amos, Nissim; Butler, John; Lee, Beomseop; Shachar, Meir H; Hu, Bing; Tian, Yuan; Hong, Jeongmin; Garcia, Davil; Ikkawi, Rabee M; Haddon, Robert C; Litvinov, Dmitri; Khizroev, Sakhrat

    2012-01-01

    This letter presents an experimental study that shows that a 3(rd) physical dimension may be used to further increase information packing density in magnetic storage devices. We demonstrate the feasibility of at least quadrupling the magnetic states of magnetic-based data storage devices by recording and reading information from nanopillars with three magnetically-decoupled layers. Magneto-optical Kerr effect microscopy and magnetic force microscopy analysis show that both continuous (thin film) and patterned triple-stack magnetic media can generate eight magnetically-stable states. This is in comparison to only two states in conventional magnetic recording. Our work further reveals that ferromagnetic interaction between magnetic layers can be reduced by combining Co/Pt and Co/Pd multilayers media. Finally, we are showing for the first time an MFM image of multilevel-3D bit patterned media with 8 discrete signal levels.

  13. 3D fibre deposition and stereolithography techniques for the design of multifunctional nanocomposite magnetic scaffolds.

    PubMed

    De Santis, Roberto; D'Amora, Ugo; Russo, Teresa; Ronca, Alfredo; Gloria, Antonio; Ambrosio, Luigi

    2015-10-01

    Magnetic nanocomposite scaffolds based on poly(ε-caprolactone) and poly(ethylene glycol) were fabricated by 3D fibre deposition modelling (FDM) and stereolithography techniques. In addition, hybrid coaxial and bilayer magnetic scaffolds were produced by combining such techniques. The aim of the current research was to analyse some structural and functional features of 3D magnetic scaffolds obtained by the 3D fibre deposition technique and by stereolithography as well as features of multimaterial scaffolds in the form of coaxial and bilayer structures obtained by the proper integration of such methods. The compressive mechanical behaviour of these scaffolds was investigated in a wet environment at 37 °C, and the morphological features were analysed through scanning electron microscopy (SEM) and X-ray micro-computed tomography. The capability of a magnetic scaffold to absorb magnetic nanoparticles (MNPs) in water solution was also assessed. confocal laser scanning microscopy was used to assess the in vitro biological behaviour of human mesenchymal stem cells (hMSCs) seeded on 3D structures. Results showed that a wide range of mechanical properties, covering those spanning hard and soft tissues, can be obtained by 3D FDM and stereolithography techniques. 3D virtual reconstruction and SEM showed the precision with which the scaffolds were fabricated, and a good-quality interface between poly(ε-caprolactone) and poly(ethylene glycol) based scaffolds was observed for bilayer and coaxial scaffolds. Magnetised scaffolds are capable of absorbing water solution of MNPs, and a preliminary information on cell adhesion and spreading of hMSCs was obtained without the application of an external magnetic field.

  14. 3D Kinetic Simulation of Plasma Jet Penetration in Magnetic Field

    NASA Astrophysics Data System (ADS)

    Galkin, Sergei A.; Bogatu, I. N.; Kim, J. S.

    2009-11-01

    A high velocity plasmoid penetration through a magnetic barrier is a problem of a great experimental and theoretical interest. Our LSP PIC code 3D fully kinetic numerical simulations of high density (10^16 cm-3) high velocity (30-140 km/sec) plasma jet/bullet, penetrating through the transversal magnetic field, demonstrate three different regimes: reflection by field, penetration by magnetic field expulsion and penetration by magnetic self-polarization. The behavior depends on plasma jet parameters and its composition: hydrogen, carbon (A=12) and C60-fullerene (A=720) plasmas were investigated. The 3D simulation of two plasmoid head-on injections along uniform magnetic field lines is analyzed. Mini rail plasma gun (accelerator) modeling is also presented and discussed.

  15. Spatial and temporal analysis of DIII-D 3D magnetic diagnostic data

    NASA Astrophysics Data System (ADS)

    Strait, E. J.; King, J. D.; Hanson, J. M.; Logan, N. C.

    2016-11-01

    An extensive set of magnetic diagnostics in DIII-D is aimed at measuring non-axisymmetric "3D" features of tokamak plasmas, with typical amplitudes ˜10-3 to 10-5 of the total magnetic field. We describe hardware and software techniques used at DIII-D to condition the individual signals and analysis to estimate the spatial structure from an ensemble of discrete measurements. Applications of the analysis include detection of non-rotating MHD instabilities, plasma control, and validation of MHD stability and 3D equilibrium models.

  16. Spatial and temporal analysis of DIII-D 3D magnetic diagnostic data.

    PubMed

    Strait, E J; King, J D; Hanson, J M; Logan, N C

    2016-11-01

    An extensive set of magnetic diagnostics in DIII-D is aimed at measuring non-axisymmetric "3D" features of tokamak plasmas, with typical amplitudes ∼10(-3) to 10(-5) of the total magnetic field. We describe hardware and software techniques used at DIII-D to condition the individual signals and analysis to estimate the spatial structure from an ensemble of discrete measurements. Applications of the analysis include detection of non-rotating MHD instabilities, plasma control, and validation of MHD stability and 3D equilibrium models.

  17. Spatial and temporal analysis of DIII-D 3D magnetic diagnostic data

    DOE PAGES

    Strait, E. J.; King, J. D.; Hanson, J. M.; ...

    2016-08-11

    An extensive set of magnetic diagnostics in DIII-D is aimed at measuring non-axisymmetric "3D" features of tokamak plasmas, with typical amplitudes ~10-3 to 10-5 of the total magnetic field. We describe hardware and software techniques used at DIII-D to condition the individual signals and analysis to estimate the spatial structure from an ensemble of discrete measurements. Lastly, applications of the analysis include detection of non-rotating MHD instabilities, plasma control, and validation of MHD stability and 3D equilibrium models.

  18. DIRECT DETECTION OF THE HELICAL MAGNETIC FIELD GEOMETRY FROM 3D RECONSTRUCTION OF PROMINENCE KNOT TRAJECTORIES

    SciTech Connect

    Zapiór, Maciej; Martinez-Gómez, David

    2016-02-01

    Based on the data collected by the Vacuum Tower Telescope located in the Teide Observatory in the Canary Islands, we analyzed the three-dimensional (3D) motion of so-called knots in a solar prominence of 2014 June 9. Trajectories of seven knots were reconstructed, giving information of the 3D geometry of the magnetic field. Helical motion was detected. From the equipartition principle, we estimated the lower limit of the magnetic field in the prominence to ≈1–3 G and from the Ampère’s law the lower limit of the electric current to ≈1.2 × 10{sup 9} A.

  19. Low field magnetic resonance imaging

    SciTech Connect

    Pines, Alexander; Sakellariou, Dimitrios; Meriles, Carlos A.; Trabesinger, Andreas H.

    2010-07-13

    A method and system of magnetic resonance imaging does not need a large homogenous field to truncate a gradient field. Spatial information is encoded into the spin magnetization by allowing the magnetization to evolve in a non-truncated gradient field and inducing a set of 180 degree rotations prior to signal acquisition.

  20. 3D Geological Model of Nihe ore deposit Constrained by Gravity and Magnetic Modeling

    NASA Astrophysics Data System (ADS)

    Qi, Guang; Yan, Jiayong; Lv, Qingtan; Zhao, Jinhua

    2016-04-01

    We present a case study on using integrated geologic model in mineral exploration at depth. Nihe ore deposit in Anhui Province, is deep hidden ore deposit which was discovered in recent years, this finding is the major driving force of deep mineral exploration work in Luzong. Building 3D elaborate geological model has the important significance for prospecting to deep or surround in this area, and can help us better understand the metallogenic law and ore-controlling regularity. A 3D geological model, extending a depth from +200m to -1500m in Nihe ore deposit, has been compiled from surface geological map, cross-section, borehole logs and amounts of geological inference. And then the 3D geological models have been given physical property parameter for calculating the potential field. Modelling the potential response is proposed as means of evaluating the viability of the 3D geological models, and the evidence of making small changes to the uncertain parts of the original 3D geological models. It is expected that the final models not only reproduce supplied prior geological knowledge, but also explain the observed geophysical data. The workflow used to develop the 3D geologic model in this study includes the three major steps, as follows: (1) Determine the basic information of Model: Defining the 3D limits of the model area, the basic geological and structural unit, and the tectonic contact relations and the sedimentary sequences between these units. (2) 3D model construction: Firstly, a series of 2D geological cross sections over the model area are built by using all kinds of prior information, including surface geology, borehole data, seismic sections, and local geologists' knowledge and intuition. Lastly, we put these sections into a 3D environment according to their profile locations to build a 3D model by using geostatistics method. (3) 3D gravity and magnetic modeling: we calculate the potential field responses of the 3D model, and compare the predicted and

  1. Resonant structure of the 3d electron`s angular distribution in a free Mn{sup +}Ion

    SciTech Connect

    Amusia, M.Y.; Dolmatov, V.K.

    1995-08-01

    The 3d-electron angular anisotropy parameter of the free Mn{sup +} ion is calculated using the {open_quotes}spin-polarized{close_quotes} random-phase approximation with exchange. Strong resonance structure is discovered, which is due to interference with the powerful 3p {yields} 3d discrete excitation. The effect of the 3p {yields} 4s transition is also noticeable. The ordering of these respective resonances with phonon energy increase proved to be opposite in angular anisotropy parameter to that in 3d-photoionization cross section. A paper describing these results was published.

  2. Introduction to nuclear magnetic resonance.

    PubMed

    Mlynárik, Vladimír

    2016-05-19

    Nuclear magnetic resonance spectroscopy is a useful tool for studying normal and pathological biochemical processes in tissues. In this review, the principles of nuclear magnetic resonance and methods of obtaining nuclear magnetic resonance spectra are briefly outlined. The origin of the most important spectroscopic parameters-chemical shifts, coupling constants, longitudinal and transverse relaxation times, and spectroscopic line intensities-is explained, and the role of these parameters in interpretation of spectra is addressed. Basic methodological concepts of localized spectroscopy and spectroscopic imaging for the study of tissue metabolism in vivo are also described.

  3. Nuclear magnetic resonance contrast agents

    DOEpatents

    Smith, P.H.; Brainard, J.R.; Jarvinen, G.D.; Ryan, R.R.

    1997-12-30

    A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC{sub 16}H{sub 14}N{sub 6}. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques. 10 figs.

  4. Nuclear magnetic resonance contrast agents

    DOEpatents

    Smith, Paul H.; Brainard, James R.; Jarvinen, Gordon D.; Ryan, Robert R.

    1997-01-01

    A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.

  5. Functional magnetic resonance imaging.

    PubMed

    Buchbinder, Bradley R

    2016-01-01

    Functional magnetic resonance imaging (fMRI) maps the spatiotemporal distribution of neural activity in the brain under varying cognitive conditions. Since its inception in 1991, blood oxygen level-dependent (BOLD) fMRI has rapidly become a vital methodology in basic and applied neuroscience research. In the clinical realm, it has become an established tool for presurgical functional brain mapping. This chapter has three principal aims. First, we review key physiologic, biophysical, and methodologic principles that underlie BOLD fMRI, regardless of its particular area of application. These principles inform a nuanced interpretation of the BOLD fMRI signal, along with its neurophysiologic significance and pitfalls. Second, we illustrate the clinical application of task-based fMRI to presurgical motor, language, and memory mapping in patients with lesions near eloquent brain areas. Integration of BOLD fMRI and diffusion tensor white-matter tractography provides a road map for presurgical planning and intraoperative navigation that helps to maximize the extent of lesion resection while minimizing the risk of postoperative neurologic deficits. Finally, we highlight several basic principles of resting-state fMRI and its emerging translational clinical applications. Resting-state fMRI represents an important paradigm shift, focusing attention on functional connectivity within intrinsic cognitive networks.

  6. Adaptive fuzzy segmentation of magnetic resonance images.

    PubMed

    Pham, D L; Prince, J L

    1999-09-01

    An algorithm is presented for the fuzzy segmentation of two-dimensional (2-D) and three-dimensional (3-D) multispectral magnetic resonance (MR) images that have been corrupted by intensity inhomogeneities, also known as shading artifacts. The algorithm is an extension of the 2-D adaptive fuzzy C-means algorithm (2-D AFCM) presented in previous work by the authors. This algorithm models the intensity inhomogeneities as a gain field that causes image intensities to smoothly and slowly vary through the image space. It iteratively adapts to the intensity inhomogeneities and is completely automated. In this paper, we fully generalize 2-D AFCM to three-dimensional (3-D) multispectral images. Because of the potential size of 3-D image data, we also describe a new faster multigrid-based algorithm for its implementation. We show, using simulated MR data, that 3-D AFCM yields lower error rates than both the standard fuzzy C-means (FCM) algorithm and two other competing methods, when segmenting corrupted images. Its efficacy is further demonstrated using real 3-D scalar and multispectral MR brain images.

  7. Magnetic resonance force microscopy with a permanent magnet on the cantilever

    SciTech Connect

    Zhang, Z.; Hammel, P.C.

    1997-02-01

    The magnetic resonance force microscope (MRFM) is a microscopic 3-D imaging instrument based on a recent proposal to detect magnetic resonance signals mechanically using a micro-mechanical resonator. MRFM has been successfully demonstrated in various magnetic resonance experiments including electron spin resonance, ferromagnetic resonances and nuclear magnetic resonance. In order to apply this ultra-high, 3-D spatial resolution technique to samples of arbitrary size and shape, the magnetic particle which generates the field gradient {del}{bold B}, (and, therefore, the force {bold F = (m {center_dot} {del}B)} between itself and the spin magnetization {bold m} of the sample) will need to be mounted on the mechanical resonator. Up to the present, all experiments have been performed with the sample mounted on the resonator. This is done, in part, to avoid the spurious response of the mechanical resonator which is generated by the variation of the magnetization of the magnetic particle as the external field is varied.

  8. Simple and Inexpensive Classroom Demonstrations of Nuclear Magnetic Resonance and Magnetic Resonance Imaging.

    ERIC Educational Resources Information Center

    Olson, Joel A.; Nordell, Karen J.; Chesnik, Marla A.; Landis, Clark R.; Ellis, Arthur B.; Rzchowski, M. S.; Condren, S. Michael; Lisensky, George C.

    2000-01-01

    Describes a set of simple, inexpensive, classical demonstrations of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) principles that illustrate the resonance condition associated with magnetic dipoles and the dependence of the resonance frequency on environment. (WRM)

  9. Magnetic and Magnetoresistive Properties of 3D Interconnected NiCo Nanowire Networks

    NASA Astrophysics Data System (ADS)

    da Câmara Santa Clara Gomes, Tristan; De La Torre Medina, Joaquín; Lemaitre, Matthieu; Piraux, Luc

    2016-10-01

    Track-etched polymer membranes with crossed nanochannels have been revealed to be most suitable as templates to produce large surface area and mechanically stable 3D interconnected nanowire (NW) networks by electrodeposition. Geometrically controlled NW superstructures made of NiCo ferromagnetic alloys exhibit appealing magnetoresistive properties. The combination of exact alloy compositions with the spatial arrangement of NWs in the 3D network is decisive to obtain specific magnetic and magneto-transport behavior. A proposed simple model based on topological aspects of the 3D NW networks is used to accurately determine the anisotropic magnetoresistance ratios. Despite of their complex topology, the microstructure of Co-rich NiCo NW networks display mixed fcc-hcp phases with the c-axis of the hcp phase oriented perpendicular to their axis. These interconnected NW networks have high potential as reliable and stable magnetic field sensors.

  10. Ballooning Stability Of Tokamak Pedestals In The Presence Of Applied 3D Magnetic Perturbations

    NASA Astrophysics Data System (ADS)

    Cote, T. B.; Hegna, C. C.; Willensdorfer, M.; Strumberger, E.; Suttrop, W.; Zohm, H.

    2016-10-01

    Applied 3d magnetic perturbations can destabilize ideal mhd ballooning modes in tokamak pedestals. In this work, we describe techniques for studying infinite-n ballooning stability of 3d equilibria deduced from vmec calculations. Full magnetic profiles from vmec are used to construct local equilibria for flux surfaces in and around the edge pedestal region. These local equilibrium calculations are coupled with ideal ballooning stability analysis to determine stability of the system for given rmp configurations. This theoretical development is motivated by recent asdex-u experiments, where toroidally localized high-n mhd activity is observed in the presence of applied 3d fields. We will attempt to explain these observations. Supported by US DOE under Grant No. DE-FG02-86ER53218.

  11. Synthesis of 3D Model of a Magnetic Field-Influenced Body from a Single Image

    NASA Technical Reports Server (NTRS)

    Wang, Cuilan; Newman, Timothy; Gallagher, Dennis

    2006-01-01

    A method for recovery of a 3D model of a cloud-like structure that is in motion and deforming but approximately governed by magnetic field properties is described. The method allows recovery of the model from a single intensity image in which the structure's silhouette can be observed. The method exploits envelope theory and a magnetic field model. Given one intensity image and the segmented silhouette in the image, the method proceeds without human intervention to produce the 3D model. In addition to allowing 3D model synthesis, the method's capability to yield a very compact description offers further utility. Application of the method to several real-world images is demonstrated.

  12. 3-D Localization Method for a Magnetically Actuated Soft Capsule Endoscope and Its Applications

    PubMed Central

    Yim, Sehyuk; Sitti, Metin

    2014-01-01

    In this paper, we present a 3-D localization method for a magnetically actuated soft capsule endoscope (MASCE). The proposed localization scheme consists of three steps. First, MASCE is oriented to be coaxially aligned with an external permanent magnet (EPM). Second, MASCE is axially contracted by the enhanced magnetic attraction of the approaching EPM. Third, MASCE recovers its initial shape by the retracting EPM as the magnetic attraction weakens. The combination of the estimated direction in the coaxial alignment step and the estimated distance in the shape deformation (recovery) step provides the position of MASCE in 3-D. It is experimentally shown that the proposed localization method could provide 2.0–3.7 mm of distance error in 3-D. This study also introduces two new applications of the proposed localization method. First, based on the trace of contact points between the MASCE and the surface of the stomach, the 3-D geometrical model of a synthetic stomach was reconstructed. Next, the relative tissue compliance at each local contact point in the stomach was characterized by measuring the local tissue deformation at each point due to the preloading force. Finally, the characterized relative tissue compliance parameter was mapped onto the geometrical model of the stomach toward future use in disease diagnosis. PMID:25383064

  13. Extensions of 1d Bgk Electron Solitary Wave Solutions To 3d Magnetized and Unmagnetized Plasmas

    NASA Astrophysics Data System (ADS)

    Chen, Li-Jen; Parks, George K.

    This paper will compare the key results for BGK electron solitary waves in 3D mag- netized and unmagnetized plasmas. For 3D magnetized plasmas with highly magnetic field-aligned electrons, our results predict that the parallel widths of the solitary waves can be smaller than one Debye length, the solitary waves can be large scale features of the magnetosphere, and the parallel width-amplitude relation has a dependence on the perpendicular size. We can thus obtain an estimate on the typical perpendicular size of the observed solitary waves assuming a series of consecutive solitary waves are in the same flux tude with a particular perpendicular span. In 3D unmagnetized plasma systems such as the neutral sheet and magnetic reconnection sites, our theory indi- cates that although mathematical solutions can be constructed as the time-stationary solutions for the nonlinear Vlasov-Poisson equations, there does not exist a param- eter range for the solutions to be physical. We conclude that single-humped solitary potential pulses cannot be self-consistently supported by charged particles in 3D un- magnetized plasmas.

  14. Experimental onset threshold and magnetic pressure pileup for 3D Sweet-Parker reconnection

    SciTech Connect

    Intrator, Thomas P; Sun, Xuan; Lapenta, Giovanni; Furno, Ivo

    2008-01-01

    In space, astrophysical and laboratory plasmas, magnetic reconnect ion converts magnetic into particle energy during unsteady, explosive events. The abrupt onset and cessation has been a long standing puzzle. We show the first three-dimensional (3D) laboratory example of onset and stagnation of Sweet-Parker type magnetic reconnection between magnetized and parallel current (flux) ropes driven by magnetohydrodynamic (MHD) attraction and 3D instability. Mutually attracting flux ropes advect and merge oppositely directed magnetic fields. Magnetic flux is annihilated, but reaches soon a threshold where magnetic flux and pressure pile up, and reconnection magnetic topology appears. This occurs when inflow speeds exceed the SweetParker speed v{sub SP} = v{sub A} / S{sup 1/2}, where v{sub A} is the Alfven speed and S is the Lundquist number for the reconnection layer, as magnetic flux arrives faster than flux annihilation can process it. Finally piled up fields generate MHD reaction forces that stall the inflow and the reconnection process.

  15. Exact spectra of strong coulomb correlations of 3-D 2-e harmonic dots in magnetic field

    NASA Astrophysics Data System (ADS)

    Aggarwal, Priyanka; Sharma, Shivalika; Kaur, Harsimran; Singh, Sunny; Hazra, Ram Kuntal

    2017-01-01

    Applications of 3-D 2-e systems have proliferated very fast due to technological advancements in wide range of phenomena from atomic landscape to mesoscopic scale. The unusual properties of atomic/mesoscopic systems are the results of interplaying charge interactions among different bound states. The non-trivial e-e correlations in electrically and/or magnetically confined systems improvise wealth of intriguing challenges at fundamental level due to lack of exact solution of Schrödinger equations. For the first time, a novel methodology of exactly finite summed coulomb correlations invented by us is so handy that even usual programmable calculator can be used to examine the electronic structures of 3-D 2-e harmonic dots in perpendicular magnetic field (symmetric gauge). Statistics of electronic levels, heat capacity measurements and magnetization (T∼1 K) are also investigated in brief to probe the degree of disorderedness.

  16. The ITER 3D Magnetic Diagnostic Response to Applied n=3 and n=4 RMP's

    SciTech Connect

    Lazerson, S A

    2014-09-01

    The ITER magnetic diagnostic response to applied n=3 and n=4 RMPs has been calculated for the 15MA scenario. The VMEC code was utilized to calculate free boundary 3D ideal MHD equilibria, where the non-stellarator symmetric terms were included in the calculation. This allows an assessment to be made of the possible boundary displacements due to RMP application in ITER. As the VMEC code assumes a continuous set of nested flux surface, the possibility of island and stochastic region formation is ignored. At the start of the current at-top (L-Mode) application of n = 4 RMP's indicates approximately 1 cm peak-to-peak displacements on the low field side of the plasma while later in the shot (H-mode) perturbations as large as 3 cm are present. Forward modeling of the ITER magnetic diagnostics indicates significant non-axisymmetric plasma response, exceeding 10% the axisymmetric signal in many of the flux loops. Magnetic field probes seem to indicate a greater robustness to 3D effects but still indicate large sensitivities to 3D effects in a number of sensors. Forward modeling of the diagnostics response to 3D equilibria allows assessment of diagnostics design and control scenarios.

  17. Nonthermal Particle Acceleration in 3D Relativistic Magnetic Reconnection in Pair Plasma

    NASA Astrophysics Data System (ADS)

    Uzdensky, Dmitri; Werner, Gregory; Zhdankin, Vladimir

    2016-10-01

    Magnetic reconnection is a fundamental plasma process that converts magnetic energy into particle kinetic energy. ``Relativistic'' reconnection is of interest in astrophysical contexts because it can accelerate particles to relativistic energies high enough for synchrotron (or inverse Compton) emission to explain observed high-energy radiation. After several 2D particle-in-cell (PIC) simulations of reconnection in pair plasmas demonstrated power-law electron-energy spectra extending to high energies, a few 3D simulations surprisingly confirmed the robustness of nonthermal particle acceleration, despite fundamental differences, such as the development of the relativistic drift-kink instability (RDKI) in 3D. We present a comprehensive PIC study of 3D relativistic pair-plasma reconnection characterizing the effect of the third dimension. We investigate how reconnection dynamics and particle acceleration depend on guide magnetic field Bz and on the simulation box length Lz in the third dimension. We find that, while the RDKI does indeed grow in 3D reconnection, it does not inhibit particle acceleration, even in the absence of guide field. This work was funded by NSF, DOE, and NASA.

  18. Noble gas magnetic resonator

    DOEpatents

    Walker, Thad Gilbert; Lancor, Brian Robert; Wyllie, Robert

    2014-04-15

    Precise measurements of a precessional rate of noble gas in a magnetic field is obtained by constraining the time averaged direction of the spins of a stimulating alkali gas to lie in a plane transverse to the magnetic field. In this way, the magnetic field of the alkali gas does not provide a net contribution to the precessional rate of the noble gas.

  19. Magnetic Resonance Force Microscope Development

    SciTech Connect

    Hammel, P.C.; Zhang, Z.; Suh, B.J.; Roukes, M.L.; Midzor, M.; Wigen, P.E.; Childress, J.R.

    1999-06-03

    Our objectives were to develop the Magnetic Resonance Force Microscope (MRFM) into an instrument capable of scientific studies of buried structures in technologically and scientifically important electronic materials such as magnetic multilayer materials. This work resulted in the successful demonstration of MRFM-detected ferromagnetic resonance (FMR) as a microscopic characterization tool for thin magnetic films. Strong FMR spectra obtained from microscopic Co thin films (500 and 1000 angstroms thick and 40 x 200 microns in lateral extent) allowed us to observe variations in sample inhomogeneity and magnetic anisotropy field. We demonstrated lateral imaging in microscopic FMR for the first time using a novel approach employing a spatially selective local field generated by a small magnetically polarized spherical crystallite of yttrium iron garnet. These successful applications of the MRFM in materials studies provided the basis for our successful proposal to DOE/BES to employ the MRF M in studies of buried interfaces in magnetic materials.

  20. Early History of Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Ramsey, N. F.

    1999-06-01

    The early history of magnetic resonance to around 1950 is discussed from the point of view of a participant in it. I. I. Rabi's theory of space quantization in a gyrating magnetic field and his molecular beam experiments in the 1930s laid the foundation of the magnetic resonance method, which he and his associates subsequently pursued and developed further at Columbia University, leading eventually to the development of NMR after World War II and the invention of the separated oscillatory fields method in 1950.

  1. Optically detected magnetic resonance imaging

    SciTech Connect

    Blank, Aharon; Shapiro, Guy; Fischer, Ran; London, Paz; Gershoni, David

    2015-01-19

    Optically detected magnetic resonance provides ultrasensitive means to detect and image a small number of electron and nuclear spins, down to the single spin level with nanoscale resolution. Despite the significant recent progress in this field, it has never been combined with the power of pulsed magnetic resonance imaging techniques. Here, we demonstrate how these two methodologies can be integrated using short pulsed magnetic field gradients to spatially encode the sample. This result in what we denote as an 'optically detected magnetic resonance imaging' technique. It offers the advantage that the image is acquired in parallel from all parts of the sample, with well-defined three-dimensional point-spread function, and without any loss of spectroscopic information. In addition, this approach may be used in the future for parallel but yet spatially selective efficient addressing and manipulation of the spins in the sample. Such capabilities are of fundamental importance in the field of quantum spin-based devices and sensors.

  2. Anisotropic heat transport in integrable and chaotic 3-D magnetic fields

    SciTech Connect

    Del-Castillo-Negrete, Diego B; Blazevski, D.; Chacon, Luis

    2012-01-01

    A study of anisotropic heat transport in 3-D chaotic magnetic fields is presented. The approach is based on the recently proposed Lagrangian-Green s function (LG) method in Ref. [1] that allows an efficient and accurate integration of the parallel transport equation applicable to general magnetic fields with local or non-local parallel flux closures. We focus on reversed shear magnetic field configurations known to exhibit separatrix reconnection and shearless transport barriers. The role of reconnection and magnetic field line chaos on temperature transport is studied. Numerical results are presented on the anomalous relaxation of radial temperature gradients in the presence of shearless Cantori partial barri- ers. Also, numerical evidence of non-local effective radial temperature transport in chaotic fields is presented. Going beyond purely parallel transport, the LG method is generalized to include finite perpendicular diffusivity, and the problem of temperature flattening inside a magnetic island is studied.

  3. Magnetic and Electronic Phase Diagram of Sr2VFeAsO3-d

    NASA Astrophysics Data System (ADS)

    Tojo, Yujiro; Shibuya, Taizo; Nakamura, Tetsuro; Shoji, Koichiro; Matoba, Masanori; Yasui, Shintaro; Itoh, Mitsuru; Kitao, Shinji; Seto, Makoto; Kamihara, Yoichi; Research Grants From Keio Univ. Collaboration; Msl Collaborative Research Project Collaboration; Joint Usage in Krri Collaboration

    2014-03-01

    Ae2MFePnO3 (so-called 21113 systems) with perovskite-type layers such as Ae2MO3, where Ae denotes alkaline earth metals, M does Sc, Ti, Cr, V and other transition metal atoms and Pn does As and P shows superconductivity at T <46 K. Sr2VFeAsO3-d is a representative compound in 21113 systems. [Zhu et al, Phys. Rev. B (2009); Ogino et al, Supercond. Sci. Technol. (2009); Ogino et al, Supercond. Sci. Technol. (2009)] Although the oxygen deficiency (d) as a function of Tc is still controversial in Sr2VFeAsO3-d, many samples have been reported as superconductors with Tc = 24-37 K. In this study, a polycrystalline Sr2VFeAsO3-d (d = ~ 0.1- 0.6) were prepared by a solid state reaction using an alumina tube in a sealed silica tube. DC electrical resistivity was measured by a four-probe technique. Magnetization measurements were performed on a superconducting quantum interference device. 57Fe Mossbauer spectra were obtained using conventional equipment. The electronic and magnetic phase diagram of Sr2VFeAsO3-d is elucidated.

  4. GHz nuclear magnetic resonance

    SciTech Connect

    Cross, T.A.; Drobny, G.; Trewhella, J.

    1994-12-01

    For the past dozen years, 500- and 600-MHz spectrometers have become available in many laboratories. The first 600-MHz NMR spectrometer (at Carnegie Mellon University) was commissioned more than 15 years ago and, until 1994, represented the highest field available for high-resolution NMR. This year, we have witnessed unprecedented progress in the development of very high field magnets for NMR spectroscopy, including the delivery of the first commercial 750-MHz NMR spectrometers. In addition, NMR signals have been obtained from 20-Tesla magnets (850 MHz for {sup 1}H`s) at both Los Alamos National Laboratory and Florida State University in the NHMFL (National High Magnetic Field Laboratory). These preliminary experiments have been performed in magnets with 100-ppm homogeneity, but a 20-Tesla magnet developed for the NHMFL will be brought to field this year with a projected homogeneity of 0.1 ppm over a 1-cm-diam spherical volume.

  5. 3-D Modeling of Magnetic Fields for the Lithium Tokamak eXperiment

    NASA Astrophysics Data System (ADS)

    Logan, N.; Berzak, L.; Kaita, R.; Majeski, R.; Menard, J.; Zakharov, L.

    2010-11-01

    The Lithium Tokamak eXperiment (LTX) is designed to investigate low-recycling operating regimes by surrounding 85% of the last closed flux surface with liquid lithium evaporated onto a copper and stainless steel shell conformal to the plasma. Fields generated by currents in this conducting shell have significant effects on magnetic configurations. To understand these effects, the commercially available code Aether [http://www.fieldp.com] is used to simulate time varying magnetic fields in a 3-D model of LTX. The model is built using LTX CAD files and divided into a regular mesh for computing the evolution of coupled electromagnetic vector quantities through time and space. Applicable boundary conditions and symmetries are analyzed. Comparisons with measured data, results from a 2-D code, and results from a 3-D code designed specifically for LTX demonstrate the possible benefits and limitations of using this commercial code.

  6. 3D position estimation using a single coil and two magnetic field sensors.

    PubMed

    Tadayon, P; Staude, G; Felderhoff, T

    2015-01-01

    This paper presents an algorithm which enables the estimation of relative 3D position of a sensor module with two magnetic sensors with respect to a magnetic field source using a single transmitting coil. Starting with the description of the ambiguity problem caused by using a single coil, a system concept comprising two sensors having a fixed spatial relation to each other is introduced which enables the unique determination of the sensors' position in 3D space. For this purpose, an iterative two-step algorithm is presented: In a first step, the data of one sensor is used to limit the number of possible position solutions. In a second step, the spatial relation between the sensors is used to determine the correct sensor position.

  7. A high-throughput in vitro ring assay for vasoactivity using magnetic 3D bioprinting

    PubMed Central

    Tseng, Hubert; Gage, Jacob A.; Haisler, William L.; Neeley, Shane K.; Shen, Tsaiwei; Hebel, Chris; Barthlow, Herbert G.; Wagoner, Matthew; Souza, Glauco R.

    2016-01-01

    Vasoactive liabilities are typically assayed using wire myography, which is limited by its high cost and low throughput. To meet the demand for higher throughput in vitro alternatives, this study introduces a magnetic 3D bioprinting-based vasoactivity assay. The principle behind this assay is the magnetic printing of vascular smooth muscle cells into 3D rings that functionally represent blood vessel segments, whose contraction can be altered by vasodilators and vasoconstrictors. A cost-effective imaging modality employing a mobile device is used to capture contraction with high throughput. The goal of this study was to validate ring contraction as a measure of vasoactivity, using a small panel of known vasoactive drugs. In vitro responses of the rings matched outcomes predicted by in vivo pharmacology, and were supported by immunohistochemistry. Altogether, this ring assay robustly models vasoactivity, which could meet the need for higher throughput in vitro alternatives. PMID:27477945

  8. Plasma response measurements of external magnetic perturbations using electron cyclotron emission and comparisons to 3D ideal MHD equilibrium

    NASA Astrophysics Data System (ADS)

    Willensdorfer, M.; Denk, S. S.; Strumberger, E.; Suttrop, W.; Vanovac, B.; Brida, D.; Cavedon, M.; Classen, I.; Dunne, M.; Fietz, S.; Fischer, R.; Kirk, A.; Laggner, F. M.; Liu, Y. Q.; Odstrčil, T.; Ryan, D. A.; Viezzer, E.; Zohm, H.; Luhmann, I. C.; The ASDEX Upgrade Team; The EUROfusion MST1 Team

    2016-11-01

    The plasma response from an external n  =  2 magnetic perturbation field in ASDEX Upgrade has been measured using mainly electron cyclotron emission (ECE) diagnostics and a rigid rotating field. To interpret ECE and ECE-imaging (ECE-I) measurements accurately, forward modeling of the radiation transport has been combined with ray tracing. The measured data is compared to synthetic ECE data generated from a 3D ideal magnetohydrodynamics (MHD) equilibrium calculated by VMEC. The measured amplitudes of the helical displacement around the outboard midplane are in reasonable agreement with the one from the synthetic VMEC diagnostics. Both exceed the predictions from the vacuum field calculations and indicate the presence of a kink response at the edge, which amplifies the perturbation. VMEC and MARS-F have been used to calculate the properties of this kink mode. The poloidal mode structure of the magnetic perturbation of this kink mode at the edge peaks at poloidal mode numbers larger than the resonant components |m|>|nq| , whereas the poloidal mode structure of its displacement is almost resonant |m|≈ |nq| . This is expected from ideal MHD in the proximity of rational surfaces. The displacement measured by ECE-I confirms this resonant response.

  9. Reconstructing the Vulcano Island evolution from 3D modeling of magnetic signatures

    NASA Astrophysics Data System (ADS)

    Napoli, Rosalba; Currenti, Gilda

    2016-06-01

    High-resolution ground and marine magnetic data are exploited for a detailed definition of a 3D model of the Vulcano Island volcanic complex. The resulting 3D magnetic imaging, obtained by 3-D inverse modeling technique, has delivered useful constraints both to reconstruct the Vulcano Island evolution and to be used as input data for volcanic hazard assessment models. Our results constrained the depth and geometry of the main geo-structural features revealing more subsurface volcanic structures than exposed ones and allowing to elucidate the relationships between them. The recognition of two different magnetization sectors, approximatively coincident with the structural depressions of Piano caldera, in the southern half of the island, and La Fossa caldera at the north, suggests a complex structural and volcanic evolution. Magnetic highs identified across the southern half of the island reflect the main crystallized feeding systems, intrusions and buried vents, whose NNW-SSE preferential alignment highlights the role of the NNW-SSE Tindari-Letojanni regional system from the initial activity of the submarine edifice, to the more recent activity of the Vulcano complex. The low magnetization area, in the middle part of the island may result from hydrothermally altered rocks. Their presence not only in the central part of the volcano edifice but also in other peripheral areas, is a sign of a more diffuse historical hydrothermal activity than in present days. Moreover, the high magnetization heterogeneity within the upper flanks of La Fossa cone edifice is an imprint of a composite distribution of unaltered and altered rocks with different mechanical properties, which poses in this area a high risk level for failure processes especially during volcanic or hydrothermal crisis.

  10. 3D low-beta magnetized plasma equilibria from external shaping

    NASA Astrophysics Data System (ADS)

    Hassam, A.; Tenbarge, J.; Landreman, M.; Dorland, W.; Sengupta, W.

    2016-10-01

    A 3D nonlinear dissipative MHD code is in development to allow relaxation to low-beta MHD equilibrium inside a shaped 3D conducting boundary with prescribed conserved axial magnetic flux and no external current. Formation of magnetic islands is expected. Heat sources would be eventually introduced to allow the possibility of non-stationary convection depending on the stability properties of the accessible MHD equilibria. The initial development will be done using the code UMHD. The initial emphasis will be on recovering expected physics in simpler 3D geometries. A primary objective is to minimize numerical boundary noise. In particular, codes which specify the normal magnetic field B.n on bounding surfaces are prone to noise generation. We plan to shape the boundary to conform to the desired field shape so that B.n is zero on the boundary. Non-orthogonal coordinates will be chosen to effect this. We will test noise reduction within the tangential field approach. Results obtained to date support this conjecture. Initial results from simple 2D code equilibria have been verified against analytic solution of equilibria in weak shaping. Initial results also recover the expected features of the Hahm- Kulsrud island formation solution. Work supported by US DOE.

  11. Magnetic Resonance Cholangiopancreatography (MRCP)

    MedlinePlus

    ... magnetic field of the MRI unit, metal and electronic items are not allowed in the exam room. ... tell the technologist if you have medical or electronic devices in your body. These objects may interfere ...

  12. Magnetic Resonance (MR) Defecography

    MedlinePlus

    ... magnetic field of the MRI unit, metal and electronic items are not allowed in the exam room. ... tell the technologist if you have medical or electronic devices in your body. These objects may interfere ...

  13. Magnetic Resonance Cholangiopancreatography (MRCP)

    MedlinePlus

    ... cholangiopancreatography or MRCP uses a powerful magnetic field, radio waves and a computer to evaluate the liver, gallbladder, ... scans, MRI does not utilize ionizing radiation. Instead, radio waves redirect alignment of hydrogen atoms that naturally exist ...

  14. 3D Design, Contruction, and Field Analysis of CIS Main Dipole Magnets

    NASA Astrophysics Data System (ADS)

    Berg, G. P. A.; Fox, W.; Friesel, D. L.; Rinckel, T.

    1997-05-01

    The lattice for CIS ( Cooler Injection Synchroton ) requires four laminated 90^circ main dipole magnets with bending radius ρ = 1.273 m, EFL = 2 m, and an edge angle of 12^circ. Optimum Cooler injection and injection in the planned 15 GeV LISS ring requires operation up to about 1.75 T. Initial operation of 1 Hz, with later upgrade to 5 Hz is planned. We will present 2D and 3D field calculations used to optimize the shape of laminations and endpacks of the magnet. Endpacks are designed to determine edge angle and to compensate hexapole components, in particular above 1.4 T where saturation becomes significant. The large dipole curvature required a new type of dipole construction. Each magnet consists of wedge shaped blocks fabricated from stamped lamination of cold rolled low carbon iron. B-stage (dry) epopy was used for bonding and insulation. The end blocks are machined to include the calculated 3D shape of the endpacks. All four magnets were mapped in the field range from 0.3 T - 1.8 T. Comparison of calculations and data in terms of B(I) curves, EFL, edge angle, and hexapole component as function of field excitation will be presented. The constructed magnets are well within expected specifications.

  15. Magnetic engineering in 3d transition metals on phosphorene by strain

    NASA Astrophysics Data System (ADS)

    Cai, Xiaolin; Niu, Chunyao; Wang, Jianjun; Yu, Weiyang; Ren, XiaoYan; Zhu, Zhili

    2017-04-01

    Using first-principles density functional theory (DFT) calculations, we systematically investigate the strain effects on the adsorption energies, magnetic ordering and electronic properties of 3d transition metal (TM) atoms (from Sc to Co) adsorbed on phosphorene (P). We find that the adsorption energy of TM can be enhanced by compressive strain whereas weakened by tensile strain. Our results show that strain plays a decisive role in the magnetic moments as well as the magnetic coupling states of TM adatoms. Importantly, the transitions from antiferromagnetic (AFM) state to ferromagnetic (FM) state or to another different AFM ordering can be induced by strain effect. In addition, we observe the semiconductor to metal or half-metal transitions in some TM@P systems by applying strain. Our findings shed a new light on precisely engineering the magnetic properties and electronic properties of the TM@P systems, which will have great potential applications in spin electronics and other related fields.

  16. A 3-D Magnetic Analysis of a Linear Alternator For a Stirling Power System

    NASA Technical Reports Server (NTRS)

    Geng, Steven M.; Schwarze, Gene E.; Niedra, Janis M.

    2000-01-01

    The NASA Glenn Research Center and the Department of Energy (DOE) are developing advanced radioisotope Stirling convertors, under contract with Stirling Technology Company (STC), for space applications. Of critical importance to the successful development of the Stirling convertor for space power applications is the development of a lightweight and highly efficient linear alternator. This paper presents a 3-D finite element method (FEM) approach for evaluating Stirling convertor linear alternators. Preliminary correlations with open-circuit voltage measurements provide an encouraging level of confidence in the model. Spatial plots of magnetic field strength (H) are presented in the region of the exciting permanent magnets. These plots identify regions of high H, where at elevated temperature and under electrical load, the potential to alter the magnetic moment of the magnets exists. This implies the need for further testing and analysis.

  17. Interventional Cardiovascular Magnetic Resonance Imaging

    PubMed Central

    Saikus, Christina E.; Lederman, Robert J.

    2010-01-01

    Cardiovascular magnetic resonance (CMR) combines excellent soft-tissue contrast, multiplanar views, and dynamic imaging of cardiac function without ionizing radiation exposure. Interventional cardiovascular magnetic resonance (iCMR) leverages these features to enhance conventional interventional procedures or to enable novel ones. Although still awaiting clinical deployment, this young field has tremendous potential. We survey promising clinical applications for iCMR. Next, we discuss the technologies that allow CMR-guided interventions and, finally, what still needs to be done to bring them to the clinic. PMID:19909937

  18. Cross modality registration of video and magnetic tracker data for 3D appearance and structure modeling

    NASA Astrophysics Data System (ADS)

    Sargent, Dusty; Chen, Chao-I.; Wang, Yuan-Fang

    2010-02-01

    The paper reports a fully-automated, cross-modality sensor data registration scheme between video and magnetic tracker data. This registration scheme is intended for use in computerized imaging systems to model the appearance, structure, and dimension of human anatomy in three dimensions (3D) from endoscopic videos, particularly colonoscopic videos, for cancer research and clinical practices. The proposed cross-modality calibration procedure operates this way: Before a colonoscopic procedure, the surgeon inserts a magnetic tracker into the working channel of the endoscope or otherwise fixes the tracker's position on the scope. The surgeon then maneuvers the scope-tracker assembly to view a checkerboard calibration pattern from a few different viewpoints for a few seconds. The calibration procedure is then completed, and the relative pose (translation and rotation) between the reference frames of the magnetic tracker and the scope is determined. During the colonoscopic procedure, the readings from the magnetic tracker are used to automatically deduce the pose (both position and orientation) of the scope's reference frame over time, without complicated image analysis. Knowing the scope movement over time then allows us to infer the 3D appearance and structure of the organs and tissues in the scene. While there are other well-established mechanisms for inferring the movement of the camera (scope) from images, they are often sensitive to mistakes in image analysis, error accumulation, and structure deformation. The proposed method using a magnetic tracker to establish the camera motion parameters thus provides a robust and efficient alternative for 3D model construction. Furthermore, the calibration procedure does not require special training nor use expensive calibration equipment (except for a camera calibration pattern-a checkerboard pattern-that can be printed on any laser or inkjet printer).

  19. Beam position controlling method for 3D optical system and its application in non-planar ring resonators.

    PubMed

    Yuan, Jie; Chen, Meixiong; Long, Xingwu; Tan, Yanyang; Kang, Zhenglong; Li, Yingying

    2012-08-13

    A novel theoretical beam position controlling method for 3D optical system has been proposed in this paper. Non-planar ring resonator, which is a typical 3D optical system, has been chosen as an example to show its application. To the best of our knowledge, the generalized ray matrices, augmented 5 × 5 ray matrices for paraxial dielectric interface transmission and paraxial optical-wedge transmission, and their detailed deducing process have been proposed in this paper for the first time. By utilizing the novel coordinate system for Gaussian beam reflection and the generalized ray matrix of paraxial optical-wedge transmission, the rules and some novel results of the optical-axis perturbations of non-planar ring resonators have been obtained. Wedge angle-induced mismatching errors of non-planar ring resonators have been found out and two experimental beam position controlling methods to effectively eliminate the wedge angle-induced mismatching errors have been proposed. All those results have been confirmed by related alignment experiments and the experimental results have been described with diagrammatic representation. These findings are important to the beam control, cavity design, and cavity alignment of high precision non-planar ring laser gyroscopes. Those generalized ray matrices and their deducing methods are valuable for ray analysis of various kinds of paraxial optical-elements and resonators. This novel theoretical beam position controlling method for 3D optical system is valuable for the controlling of various kinds of 3D optical systems.

  20. Magnetic resonance apparatus

    DOEpatents

    Jackson, Jasper A.; Cooper, Richard K.

    1982-01-01

    Means for producing a region of homogeneous magnetic field remote from the source of the field, wherein two equal field sources are arranged axially so their fields oppose, producing a region near the plane perpendicular to the axis midway between the sources where the radial component of the field goes through a maximum. Near the maximum, the field is homogeneous over prescribed regions.

  1. Steady state reconnection at a single 3D magnetic null point

    NASA Astrophysics Data System (ADS)

    Galsgaard, K.; Pontin, D. I.

    2011-05-01

    Aims: We systematically stress a rotationally symmetric 3D magnetic null point by advecting the opposite footpoints of the spine axis in opposite directions. This stress eventually concentrates in the vicinity of the null point, thereby forming a local current sheet through which magnetic reconnection takes place. The aim is to look for a steady state evolution of the current sheet dynamics, which may provide scaling relations for various characteristic parameters of the system. Methods: The evolution is followed by solving numerically the non-ideal MHD equations in a Cartesian domain. The null point is embedded in an initially constant density and temperature plasma. Results: It is shown that a quasi-steady reconnection process can be set up at a 3D null by continuous shear driving. It appears that a true steady state is unlikely to be realised because the current layer tends to grow until it is restricted by the geometry of the computational domain and the imposed driving profile. However, ratios between characteristic quantities clearly settle after some time to stable values, so that the evolution is quasi-steady. The experiments show a number of scaling relations, but they do not provide a clear consensus for extending to lower magnetic resistivity or faster driving velocities. More investigations are needed to fully clarify the properties of current sheets at magnetic null points.

  2. Magnetospheric Magnetic Reconnection with Southward IMF by a 3D EMPM Simulation

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Yan, X. Y.; Cai, D. S.; Lembege, B.

    2004-01-01

    We report our new simulation results on magnetospheric magnetic reconnection with southward IMF using a 3D EMPM model, with greater resolution and more particles using the parallelized 3D HPF TRISTAN code on VPP5000 supercomputer. Main parameters used in the new simulation are: domain size is 215 x 145 x 145, grid size = 0.5 Earth radius, initial particle number is 16 per cell, the IMF is southward. Arrival of southward IMF will cause reconnection in the magnetopause, thus allowing particles to enter into the inner magnetosphere. Sunward and tailward high particle flow are observed by satellites, and these phenomena are also observed in the simulation near the neutral line (X line) of the near-Earth magnetotail. This high particle flow goes along with the reconnected island. The magnetic reconnection process contributes to direct plasma entry between the magnetosheath to the inner magnetosphere and plasma sheet, in which the entry process eats the magnetosheath plasma to plasma sheet temperatures. We investigate magnetic, electric fields, density, and current during this magnetic reconnection with southward IMF. Further investigation with this simulation will provide insight into unsolved problems, such as the triggering of storms and substorms, and the storm-substorm relationship. New results will be presented at the meeting.

  3. An approach to 3D magnetic field calculation using numerical and differential algebra methods

    SciTech Connect

    Caspi, S.; Helm, M.; Laslett, L.J.; Brady, V.O.

    1992-07-17

    Motivated by the need for new means for specification and determination of 3D fields that are produced by electromagnetic lens elements in the region interior to coil windings and seeking to obtain techniques that will be convenient for accurate conductor placement and dynamical study of particle motion, we have conveniently gene the representation of a 2D magnetic field to 3D. We have shown that the 3 dimensioal magnetic field components of a multipole magnet in the curl-fire divergence-fire region near the axis r=0 can be derived from one dimensional functions A{sub n}(z) and their derivatives (part 1). In the region interior to coil windings of accelerator magnets the three spatial components of magnet fields can be expressed in terms of harmonic components'' proportional to functions sin (n{theta}) or cos (n{theta}) of the azimuthal angle. The r,z dependence of any such component can then be expressed in terms of powers of r times functions A{sub n}(z) and their derivatives. For twodimensional configurations B{sub z} of course is identically zero, the derivatives of A{sub n}(z) vanish, and the harmonic components of the transverse field then acquire a simple proportionality B{sub r,n} {proportional to} r{sup n-1} sin (n{theta}),B{sub {theta},n} {proportional to} r{sup n-1} cos (n{theta}), whereas in a 3-D configuration the more complex nature of the field gives rise to additional so-called psuedomultipole'' components as judged by additional powers of r required in the development of the field. Computation of the 3-D magnetic field arising at a sequence of field points, as a direct result of a specified current configuration or coil geometry, can be calculated explicitly through use of the Biot-Savart law and from such data the coefficients can then be derived for a general development of the type indicated above. We indicate, discuss, and illustrate two means by which this development may be performed.

  4. A fast approach to 3D HSQC-based spectroscopy based on a Fourier phase encoding of pre-targeted resonances

    NASA Astrophysics Data System (ADS)

    Lin, Yulan; Smith, Pieter E. S.; Zhang, Zhiyong; Frydman, Lucio

    2017-01-01

    Multidimensional Nuclear Magnetic Resonance (NMR) provides a unique window into structure and dynamics at an atomic level. Traditionally, given the scan-by-scan time modulation involved in these experiments, the duration of nD NMR increases exponentially with spectral dimensionality. In addition, acquisition times increase as the number of spectral elements being sought in each indirect domain - given by the ratio between the spectral bandwidth being targeted and the resolution desired. These long sampling times can be substantially reduced by exploiting information that is often available from lower-dimensionality acquisitions. This work presents a novel approach that exploits previous 2D information to speed up the acquisition of 3D spectra, based on what we denote as a Time-Optimized FouriEr Encoding (TOFEE) of pre-targeted peaks. Such 3D TOFEE experiments, which present points in common with Hadamard-encoded 3D acquisitions, do not necessarily require more scans than their 2D counterparts. This is here demonstrated based on extensions of 2D Heteronuclear Single-quantum Coherence (HSQC) experiments, to 3D HSQC-TOCSY or 3D HSQC-NOESY acquisitions. The theoretical basis of this new approach is given, and experimental demonstrations are presented on small molecule and protein-based model systems.

  5. Three-dimensional magnetic resonance cardiac imaging shows initial promise

    SciTech Connect

    Not Available

    1988-04-15

    Three-dimensional magnetic resonance imaging (3-D MRI) of the heart is already receiving encouraging reviews from heart surgeons, says Michael Vannier, MD, an associate professor of radiology at Washington University School of Medicine, St. Louis. In fact, the demand for his group's 3-D images is becoming overwhelming, Vannier says. So far, the group has used 3-D MRI to evaluate congenital heart disease. The advantage of the 3-D system is that, even to an untrained eye, anomalies are apparent and the images can even be animated. Many of the patients are infants, who are sedated while the images are acquired. When the information is combined, the averaged image produced represents a slice about 5 mm thick. The computer then stacks a number of those images together to make the 3-D image. Total scanning takes about one hour.

  6. Analysis of the 3D magnetic field and its errors for undulators with iron poles

    SciTech Connect

    Ingold, G.; Bahrdt, J.; Gaupp, A.

    1995-12-31

    The attainable field strength and field quality, such as the optical phase error, the electron beam displacement within the undulator and higher order multipoles of the magnetic field, are discussed. These issues are critical to the design and construction of short period undulators for use in short wavelength FEL or for operation in third generation light sources. We discuss two approaches: (i) For superferric undulators the construction of a full length device would rely on the optimum sorting of precision machined undulator segments. Magnetic data on segments with 20 periods (period length 8.80mm) will be presented. (ii) For hybrid undulators the sorting has to be done on individual poles and magnets. For this approach typical error sources such as machining tolerances, magnetization errors of the permanent magnet material and assembly errors are modeled in 3D and compared to induced errors on an existing hybrid undulator segment. In case of undulators having a full length of hundred periods at least five times as many individual parts have to be characterized. This should be done automatically where both the mechanical and magnetic data before and after the assembly of the magnetic structure are recorded in one step. A CNC programmable measuring device suitable for this task will shortly be presented.

  7. An orientation measurement method based on Hall-effect sensors for permanent magnet spherical actuators with 3D magnet array.

    PubMed

    Yan, Liang; Zhu, Bo; Jiao, Zongxia; Chen, Chin-Yin; Chen, I-Ming

    2014-10-24

    An orientation measurement method based on Hall-effect sensors is proposed for permanent magnet (PM) spherical actuators with three-dimensional (3D) magnet array. As there is no contact between the measurement system and the rotor, this method could effectively avoid friction torque and additional inertial moment existing in conventional approaches. Curved surface fitting method based on exponential approximation is proposed to formulate the magnetic field distribution in 3D space. The comparison with conventional modeling method shows that it helps to improve the model accuracy. The Hall-effect sensors are distributed around the rotor with PM poles to detect the flux density at different points, and thus the rotor orientation can be computed from the measured results and analytical models. Experiments have been conducted on the developed research prototype of the spherical actuator to validate the accuracy of the analytical equations relating the rotor orientation and the value of magnetic flux density. The experimental results show that the proposed method can measure the rotor orientation precisely, and the measurement accuracy could be improved by the novel 3D magnet array. The study result could be used for real-time motion control of PM spherical actuators.

  8. Magnetic Resonance Image Wavelet Enhancer

    DTIC Science & Technology

    2007-11-02

    1Departamento de Ingenieria Electrica, UAM Iztapalapa, Mexico−DF, 09340, Mexico email:arog@xanum.uam.mx. Magnetic Resonance Centre, School of Physics...Number Task Number Work Unit Number Performing Organization Name(s) and Address(es) Departamento de Ingenieria Electrica, UAM Iztapalapa, Mexico-DF

  9. Magnetic resonance apparatus

    DOEpatents

    Jackson, J.A.; Cooper, R.K.

    1980-10-10

    The patent consists of means for producing a region of homogeneous magnetic field remote from the source of the field, wherein two equal field sources are arranged axially so their fields oppose, producing a region near the plane perpendicular to the axis midway between the sources where the radial correspondent of the field goes through a maximum. Near the maximum, the field is homogeneous over prescribed regions.

  10. Magnetic Resonance Imaging (MRI): Brain (For Parents)

    MedlinePlus

    ... to 2-Year-Old Magnetic Resonance Imaging (MRI): Brain KidsHealth > For Parents > Magnetic Resonance Imaging (MRI): Brain ... child may be given headphones to listen to music or earplugs to block the noise, and will ...

  11. Your Radiologist Explains Magnetic Resonance Angiography (MRA)

    MedlinePlus

    ... Sponsored by Image/Video Gallery Your Radiologist Explains Magnetic Resonance Angiography (MRA) Transcript Welcome to Radiology Info ... I’d like to talk with you about magnetic resonance angiography, or as it’s commonly known, MRA. ...

  12. Measurements of the 3D boundary distortion due to external n=2 magnetic perturbations in comparison to ideal MHD

    NASA Astrophysics Data System (ADS)

    Willensdorfer, Matthias; Suttrop, Wolfgang; Strumberger, Erika; Zohm, Hartmut; Orain, Francois; Kirk, Andrew; Ryan, David; ASDEX Upgrade Team Team

    2016-10-01

    Best ELM mitigation/suppression at DIII-D and AUG are achieved by external magnetic perturbation (MP) fields, when the applied poloidal mode spectrum is aligned with the mode (kink) at the edge that is most strongly amplified by the plasma. This kink mode causes a 3D displacement of the plasma boundary, which is characterized at AUG using data from toroidally localized high resolution diagnostics and rigid rotating MP-fields with different applied poloidal mode spectra. Various profile and imaging diagnostics, e.g. electron cyclotron emission (ECE), are used to determine the amplitude, the penetration and the poloidal mode structure of the displacement around the outer midplane. The displacement around the X-point/plasma top, which is related to ELM mitigation, is measured using a new steerable ECE and SOFT X-ray. These measurements are compared to MHD codes like JOREK, MARS-F and VMEC. As predicted by MHD, the measured amplitudes clearly exceed the vacuum field calculations. The displacement measured by imaging ECE indicates a resonant response, although the calculated magnetic structure of this edge kink peaks at poloidal mode numbers larger than the resonant components.

  13. 1-D and 2-D resonances in an Alpine valley identified from ambient noise measurements and 3-D modelling

    NASA Astrophysics Data System (ADS)

    Le Roux, Olivier; Cornou, Cécile; Jongmans, Denis; Schwartz, Stéphane

    2012-09-01

    H/V spectral ratios are regularly used for estimating the bedrock depth in 1-D like basins exhibiting smooth lateral variations. In the case of 2-D or 3-D pronounced geometries, observational and numerical studies have shown that H/V curves exhibit peculiar shapes and that the H/V frequency generally overestimates 1-D theoretical resonance frequency. To investigate the capabilities of the H/V method in complex structures, a detailed comparison between measured and 3-D-simulated ambient vibrations was performed in the small-size lower Romanche valley (French Alps), which shows significant variations in geometry, downstream and upstream the Séchilienne basin. Analysing the H/V curve characteristics, two different wave propagation modes were identified along the valley. Relying on previous geophysical investigation, a power-law relationship was derived between the bedrock depth and the H/V peak frequency, which was used for building a 3-D model of the valley geometry. Simulated and experimental H/V curves were found to exhibit quite similar features in terms of curve shape and peak frequency values, validating the 3-D structure. This good agreement also evidenced two different propagation modes in the valley: 2-D resonance in the Séchilienne basin and 1-D resonance in the external parts. This study underlines the interest of H/V curves for investigating complex basin structures.

  14. Proton magnetic resonance spectrum of polywater.

    PubMed

    Petsko, G A

    1970-01-09

    With the aid of a time average computer, the proton magnetic resonance spectrum of anomalous water (polywater) is obtained. The spectrum conisists of a single broad resonance shifted approximately 300 hertz downfield from the resonance of ordinary water.

  15. 3D linear inversion of magnetic susceptibility data acquired by frequency domain EMI

    NASA Astrophysics Data System (ADS)

    Thiesson, J.; Tabbagh, A.; Simon, F.-X.; Dabas, M.

    2017-01-01

    Low induction number EMI instruments are able to simultaneously measure a soil's apparent magnetic susceptibility and electrical conductivity. This family of dual measurement instruments is highly useful for the analysis of soils and archeological sites. However, the electromagnetic properties of soils are found to vary over considerably different ranges: whereas their electrical conductivity varies from ≤ 0.1 to ≥ 100 mS/m, their relative magnetic permeability remains within a very small range, between 1.0001 and 1.01 SI. Consequently, although apparent conductivity measurements need to be inverted using non-linear processes, the variations of the apparent magnetic susceptibility can be approximated through the use of linear processes, as in the case of the magnetic prospection technique. Our proposed 3D inversion algorithm starts from apparent susceptibility data sets, acquired using different instruments over a given area. A reference vertical profile is defined by considering the mode of the vertical distributions of both the electrical resistivity and of the magnetic susceptibility. At each point of the mapped area, the reference vertical profile response is subtracted to obtain the apparent susceptibility variation dataset. A 2D horizontal Fourier transform is applied to these variation datasets and to the dipole (impulse) response of each instrument, a (vertical) 1D inversion is performed at each point in the spectral domain, and finally the resulting dataset is inverse transformed to restore the apparent 3D susceptibility variations. It has been shown that when applied to synthetic results, this method is able to correct the apparent deformations of a buried object resulting from the geometry of the instrument, and to restore reliable quantitative susceptibility contrasts. It also allows the thin layer solution, similar to that used in magnetic prospection, to be implemented. When applied to field data it initially delivers a level of contrast

  16. Tuning the Origin of Magnetic Relaxation by Substituting the 3d or Rare-Earth Ions into Three Isostructural Cyano-Bridged 3d-4f Heterodinuclear Compounds.

    PubMed

    Zhang, Yan; Guo, Zhen; Xie, Shuang; Li, Hui-Li; Zhu, Wen-Hua; Liu, Li; Dong, Xun-Qing; He, Wei-Xun; Ren, Jin-Chao; Liu, Ling-Zhi; Powell, Annie K

    2015-11-02

    Three isostructural cyano-bridged 3d-4f compounds, [YFe(CN)6(hep)2(H2O)4] (1), [DyFe(CN)6(hep)2(H2O)4] (2), and [DyCo(CN)6(hep)2(H2O)4] (3), were successfully assembled by site-targeted substitution of the 3d or rare-earth ions. All compounds have been structurally characterized to display slightly distorted pentagonal-bipyramidal local coordination geometry around the rare-earth ions. Magnetic analyses revealed negligible magnetic coupling in compound 1, antiferromagnetic intradimer interaction in 2, and weak ferromagnetic coupling through dipolar-dipolar interaction in 3. Under an applied direct-current (dc) field, 1 (Hdc = 2.5 kOe, τ0 = 1.3 × 10(-7) s, and Ueff/kB = 23 K) and 3 (Hdc = 2.0 kOe, τ0 = 7.1 × 10(-11) s, and Ueff/kB = 63 K) respectively indicated magnetic relaxation behavior based on a single [Fe(III)]LS ion and a Dy(III) ion; nevertheless, 2 (Hdc = 2.0 kOe, τ0 = 9.7 × 10(-8) s, and Ueff/kB = 23 K) appeared to be a single-molecule magnet based on a cyano-bridged DyFe dimer. Compound 1, which can be regarded as a single-ion magnet of the [Fe(III)]LS ion linked to a diamagnetic Y(III) ion in a cyano-bridged heterodimer, represents one of the rarely investigated examples based on a single Fe(III) ion explored in magnetic relaxation behavior. It demonstrated that the introduction of intradimer magnetic interaction of 2 through a cyano bridge between Dy(III) and [Fe(III)]LS ions negatively affects the energy barrier and χ″(T) peak temperature compared to 3.

  17. Sawtooth mitigation in 3D MHD tokamak modelling with applied magnetic perturbations

    NASA Astrophysics Data System (ADS)

    Bonfiglio, D.; Veranda, M.; Cappello, S.; Chacón, L.; Escande, D. F.

    2017-01-01

    The effect of magnetic perturbations (MPs) on the sawtoothing dynamics of the internal kink mode in the tokamak is discussed in the framework of nonlinear 3D MHD modelling. Numerical simulations are performed with the pixie3d code (Chacón 2008 Phys. Plasmas 15 056103) based on a D-shaped configuration in toroidal geometry. MPs are applied as produced by two sets of coils distributed along the toroidal direction, one set located above and the other set below the outboard midplane, like in experimental devices such as DIII-D and ASDEX Upgrade. The capability of n  =  1 MPs to affect quasi-periodic sawteeth is shown to depend on the toroidal phase difference Δ φ between the perturbations produced by the two sets of coils. In particular, sawtooth mitigation is obtained for the Δ φ =π phasing, whereas no significant effect is observed for Δ φ =0 . Numerical findings are explained by the interplay between different poloidal harmonics in the spectrum of applied MPs, and appear to be consistent with experiments performed in the DIII-D device. Sawtooth mitigation and stimulation of self-organized helical states by applied MPs have been previously demonstrated in both circular tokamak and reversed-field pinch (RFP) experiments in the RFX-mod device, and in related 3D MHD modelling.

  18. 3D Magnetic Measurements of Kink and Locked Modes in DIII-D

    NASA Astrophysics Data System (ADS)

    King, J. D.; Strait, E. J.; Hanson, J. M.; Paz-Soldan, C.; Logan, N. C.; Lanctot, M. J.; Shiraki, D.

    2013-10-01

    The DIII-D magnetics diagnostic has been greatly expanded to fully characterize non-axisymmetric ``3D'' fields. Five poloidal locations now recover n <= 3 , while new HFS arrays provide poloidal spectral resolution of 7.4 cm. Initial measurements suggest externally driven kink structures deviate from MARS-F and IPEC models. These variations extend to the ideal regime, where toroidal agreement is observed. The plasma response to an n = 3 RMP increases monotonically as beta increases and q95 decreases, contrary to predictions of a screening to kink valley. Finally, the temporal evolution of the 3D eigenstructure of a slowly rotating (5 Hz) quasi-static, born locked, tearing mode provides the first evidence of an appreciable n = 2 error field, and an estimate of the phase for future correction. This new 3D capability will be used to understand and optimize control of RWMs, NTV torque, ELMs, and error field correction to extend stable tokamak operation. Work supported in part by the US Department of Energy under DE-AC05-00OR22725, DE-FC02-04ER54698, DE-FG02-95ER54309, DE-AC02-09CH11466, DE-FG02-04ER54761 and DE-AC52-07NA27344.

  19. 3D In Vitro Model for Breast Cancer Research Using Magnetic Levitation and Bioprinting Method.

    PubMed

    Leonard, Fransisca; Godin, Biana

    2016-01-01

    Tumor microenvironment composition and architecture are known as a major factor in orchestrating the tumor growth and its response to various therapies. In this context, in vivo studies are necessary to evaluate the responses. However, while tumor cells can be of human origin, tumor microenvironment in the in vivo models is host-based. On the other hand, in vitro studies in a flat monoculture of tumor cells (the most frequently used in vitro tumor model) are unable to recapitulate the complexity of tumor microenvironment. Three-dimensional (3D) in vitro cell cultures of tumor cells have been proven to be an important experimental tool in understanding mechanisms of tumor growth, response to therapeutics, and transport of nutrients/drugs. We have recently described a novel tool to create 3D co-cultures of tumor cells and cells in the tumor microenvironment. Our method utilizes magnetic manipulation/levitation of the specific ratios of tumor cells and cells in the tumor microenvironment (from human or animal origin) aiding in the formation of tumor spheres with defined cellular composition and density, as quickly as within 24 h. This chapter describes the experimental protocols developed to model the 3D structure of the cancer environment using the above method.

  20. 3D in vitro model for breast cancer research using magnetic levitation and bioprinting method

    PubMed Central

    Leonard, Fransisca; Godin, Biana

    2016-01-01

    Summary Tumor microenvironment composition and architecture are known as a major factor in orchestrating the tumor growth and its response to various therapies. In this context, in vivo studies are necessary to evaluate the responses. However, while tumor cells can be of human origin, tumor microenvironment in the in vivo models is host-based. On the other hand, in vitro studies in a flat monoculture of tumor cells (the most frequently used in vitro tumor model) are unable to recapitulate the complexity of tumor microenvironment. Three-dimensional (3D) in vitro cell cultures of tumor cells have been proven to be an important experimental tool in understanding mechanisms of tumor growth, response to therapeutics and transport of nutrients/drugs. We have recently described a novel tool to create 3D co-cultures of tumor cells and cells in the tumor microenvironment. Our method utilizes magnetic manipulation/levitation of the specific ratios of tumor cells and cells in the tumor microenvironment (from human or animal origin) aiding in the formation of tumor spheres with defined cellular composition and density, as quickly as within 24 hours. This chapter describes the experimental protocols developed to model the 3D structure of the cancer environment using the above method. PMID:26820961

  1. Magnetic Damping of g-Jitter Driven Flows: 3-D Calculations

    NASA Technical Reports Server (NTRS)

    Shang, D. Y.; Li, B. Q.; deGroh, H. C.

    1997-01-01

    A 3-D numerical model is developed to represent the oscillating natural convection induced in a cylindrical cavity filled with Ga-doped germanium with and without the presence of an external magnetic field. The model is developed based on the penalty-finite element solution of the equations describing the transport of momentum, heat and solutal element as well as the electromagnetic field distribution in the melt pool. Automatic time step control is applied to help speed up the calculations. Numerical simulations are conducted to study the convection and magnetic damping effects as a function of frequency, directions and amplitudes of g-jitter and also the direction and magnitudes of the applied magnetic fields. The results show that the g-jitter driven flow is time dependent and exhibits a complex recirculating convection pattern in three dimensions and that an applied magnetic field can be employed to suppress this deleterious convective flow and both magnitude and orientation of the applied field are important in magnetic damping of the g-jitter induced convective flows.

  2. Heat Transfer Affected by Transverse Magnetic Field using 3D Modeling of Arc Plasma

    NASA Astrophysics Data System (ADS)

    Maeda, Yoshifumi; Tanaka, Tatsuro; Yamamoto, Shinji; Iwao, Toru

    2016-10-01

    Gas shielded metal arc welding is used to join the various metal because this is the high quality joining technology. Thus, this welding is used for a welding of large buildings such as bridges and LNG tanks. However, the welding defect caused by the heat transfer decrement may occur with increasing the wind velocity. This is because that the convection loss increases because the arc deflects to leeward side with increasing the wind velocity. In order to prevent from the arc deflection, it is used that the transverse magnetic field is applied to the arc. However, the arc deflection occurs with increasing the transverse magnetic field excessively. The energy balance of the arc is changed with increasing the convection loss caused by the arc deflection, and the heat transfer to the anode decreases. Therefore, the analysis including the arc and anode is necessary to elucidate the heat transfer to the anode. In this paper, the heat transfer affected by the transverse magnetic field using 3D modeling of the arc plasma is elucidated. The heat transfer to the anode is calculated by using the EMTF(electromagnetic thermal fluid) simulation with increasing the transverse magnetic field. As a result, the heat transfer decreased with increasing the transverse magnetic field.

  3. 2D and 3D ordered arrays of Co magnetic nanowires

    NASA Astrophysics Data System (ADS)

    Garcia, J.; Prida, V. M.; Vega, V.; Rosa, W. O.; Caballero-Flores, R.; Iglesias, L.; Hernando, B.

    2015-06-01

    Cobalt nanowire arrays spatially distributed in 2D and 3D arrangements have been performed by pulsed electrodeposition into the pores of planar and cylindrical nanoporous anodic alumina membranes, respectively. Morphological characterization points out the good filling factor reached by electroplated Co nanowires in both kinds of alumina membranes exhibiting hexagonally self-ordered porous structures. Co nanowires grown in both kinds of alumina templates exhibit the same crystalline phases. DC magnetometry and First Order Reversal Curve (FORC) analysis were carried out in order to determine the overall magnetic behavior for both nanowire array geometries. It is found that when the Co nanowires of two kinds of arrays are perpendicularly magnetized, both hysteresis loops are identical, suggesting that neither the intrinsic magnetic behavior of the nanowires nor the collective one depend on the arrays geometry. FORC analysis performed along the radial direction of the Co nanowire arrays embedded in the cylindrical alumina template reveals that the contribution of each nanowire to the magnetization reversal process involves its specific orientation with respect to the applied field direction. Furthermore, the comparison between the magnetic properties for both kinds of Co nanowire arrays allows discussing about the effect of the cylindrical geometry of the template on the magnetostatic interaction among nanowires.

  4. Calculating Pressure-Driven Current Near Magnetic Islands for 3D MHD Equilibria

    NASA Astrophysics Data System (ADS)

    Radhakrishnan, Dhanush; Reiman, Allan

    2016-10-01

    In general, 3D MHD equilibria in toroidal plasmas do not result in nested pressure surfaces. Instead, islands and chaotic regions appear in the equilibrium. Near small magnetic islands, the pressure varies within the flux surfaces, which has a significant effect on the pressure-driven current, introducing singularities. Previously, the MHD equilibrium current near a magnetic island was calculated, including the effect of ``stellarator symmetry,'' wherein the singular components of the pressure-driven current vanish [A. H. Reiman, Phys. Plasmas 23, 072502 (2016)]. Here we first solve for pressure in a cylindrical plasma from the heat diffusion equation, after adding a helical perturbation. We then numerically calculate the corresponding Pfirsch-Schluter current. At the small island limit, we compare the pressure-driven current with the previously calculated solution, and far from the island, we recover the solution for nested flux surfaces. Lastly, we compute the current for a toroidal plasma for symmetric and non-symmetric geometries.

  5. Study of the internal magnetic field of Mercury through 3D hybrid simulations

    NASA Astrophysics Data System (ADS)

    Leclercq, Ludivine; Marcel Chanteur, Gerard; Modolo, Ronan; Leblanc, Francois; Schmidt, Carl; Langlais, Benoît; Thebault, Erwan

    2016-10-01

    In 1974, Mariner 10 discovered the intrinsic magnetic field of Mercury which interacts with the solar wind, leading to the formation of a magnetosphere. In spite of the recent MESSENGER observations, this magnetosphere remains quite unknown, especially in the Southern hemisphere. In order to improve our understanding of the Hermean magnetosphere, and to prepare the Bepi-Colombo mission (ESA/JAXA), we simulated the magnetized environment of Mercury using the model named LatHyS (LATMOS Hybrid Simulation). LatHyS is a 3D parallel multi-species hybrid code which has been applied to Mars, Titan and Ganymede, which has recently be improved by the implementation of a multi-grid method allowing to refine the spatial resolution near the planetary object (40 km in the case of Mercury). In order to investigate the Hermean environment, several hybrid simulations have been performed considering different internal field models, and results are compared with MESSENGER observations.

  6. A series of rare earth complexes with novel non-interpenetrating 3D networks: synthesis, structures, magnetic and optical properties.

    PubMed

    Wei, Xiao-Hua; Yang, Lin-Yan; Liao, Sheng-Yun; Zhang, Ming; Tian, Jin-Lei; Du, Pei-Yao; Gu, Wen; Liu, Xin

    2014-04-21

    A series of metal-organic framework {Ln(BCPBA)(H2O)}n {Ln = Nd (1), Sm (2), Eu (3), Tb (4), Dy (5)}; {[Ln(BCPBA)(H2O)](H2O)}n {Ln = Pr (6), Gd (7)} have been synthesized through the hydrothermal synthesis method. These compounds possess non-interpenetrating 3D networks with 10.1438 Å× 17.9149 Å rhombic channels along the [001] direction. The results of temperature-dependent magnetic susceptibility measurements indicate that compounds 4 and 7 exhibit Ln(III)Ln(III) antiferromagnetic interactions, while compound 5 exhibits Ln(III)Ln(III) ferromagnetic interactions. Frequency dependent out-of-phase signals were observed in alternating current (ac) magnetic susceptibility measurements which indicate that they have slow magnetic relaxation characteristics. The luminescent properties of 1, 2, 3, 4, and 5 are also discussed. Due to the good match between the lowest triplet state of the ligand and the resonant energy level of the lanthanide ion, compound 4 has longer fluorescence lifetime (τ1 = 400.0000 ms, τ2 = 1143.469 ms) and higher quantum yield (Φ = 42%) compared with other compounds.

  7. Effects of 2D and 3D Error Fields on the SAS Divertor Magnetic Topology

    NASA Astrophysics Data System (ADS)

    Trevisan, G. L.; Lao, L. L.; Strait, E. J.; Guo, H. Y.; Wu, W.; Evans, T. E.

    2016-10-01

    The successful design of plasma-facing components in fusion experiments is of paramount importance in both the operation of future reactors and in the modification of operating machines. Indeed, the Small Angle Slot (SAS) divertor concept, proposed for application on the DIII-D experiment, combines a small incident angle at the plasma strike point with a progressively opening slot, so as to better control heat flux and erosion in high-performance tokamak plasmas. Uncertainty quantification of the error fields expected around the striking point provides additional useful information in both the design and the modeling phases of the new divertor, in part due to the particular geometric requirement of the striking flux surfaces. The presented work involves both 2D and 3D magnetic error field analysis on the SAS strike point carried out using the EFIT code for 2D equilibrium reconstruction, V3POST for vacuum 3D computations and the OMFIT integrated modeling framework for data analysis. An uncertainty in the magnetic probes' signals is found to propagate non-linearly as an uncertainty in the striking point and angle, which can be quantified through statistical analysis to yield robust estimates. Work supported by contracts DE-FG02-95ER54309 and DE-FC02-04ER54698.

  8. Magnetic resonance imaging as a tool for extravehicular activity analysis

    NASA Technical Reports Server (NTRS)

    Dickenson, R.; Lorenz, C.; Peterson, S.; Strauss, A.; Main, J.

    1992-01-01

    The purpose of this research is to examine the value of magnetic resonance imaging (MRI) as a means of conducting kinematic studies of the hand for the purpose of EVA capability enhancement. After imaging the subject hand using a magnetic resonance scanner, the resulting 2D slices were reconstructed into a 3D model of the proximal phalanx of the left hand. Using the coordinates of several landmark positions, one is then able to decompose the motion of the rigid body. MRI offers highly accurate measurements due to its tomographic nature without the problems associated with other imaging modalities for in vivo studies.

  9. Pediatric Body Magnetic Resonance Imaging.

    PubMed

    Kandasamy, Devasenathipathy; Goyal, Ankur; Sharma, Raju; Gupta, Arun Kumar

    2016-09-01

    Magnetic resonance imaging (MRI) is a radiation-free imaging modality with excellent contrast resolution and multiplanar capabilities. Since ionizing radiation is an important concern in the pediatric population, MRI serves as a useful alternative to computed tomography (CT) and also provides additional clues to diagnosis, not discernible on other investigations. Magnetic resonance cholangiopancreatography (MRCP), urography, angiography, enterography, dynamic multiphasic imaging and diffusion-weighted imaging provide wealth of information. The main limitations include, long scan time, need for sedation/anesthesia, cost and lack of widespread availability. With the emergence of newer sequences and variety of contrast agents, MRI has become a robust modality and may serve as a one-stop shop for both anatomical and functional information.

  10. New Era in 3-D Modeling of Convection and Magnetic Dynamos in Stellar Envelopes and Cores

    NASA Astrophysics Data System (ADS)

    Toomre, J.; Augustson, K. C.; Brown, B. P.; Browning, M. K.; Brun, A. S.; Featherstone, N. A.; Miesch, M. S.

    2012-09-01

    The recent advances in asteroseismology and spectropolarimetry are beginning to provide estimates of differential rotation and magnetic structures for a range of F and G-type stars possessing convective envelopes, and in A-type stars with convective cores. It is essential to complement such observational work with theoretical studies based on 3-D simulations of highly turbulent convection coupled to rotation, shear and magnetic fields in full spherical geometries. We have so employed the anelastic spherical harmonic (ASH) code, which deals with compressible magnetohydrodynamics (MHD) in spherical shells, to examine the manner in which the global-scale convection can establish differential rotation and meridional circulations under current solar rotation rates, and these make good contact with helioseismic findings. For younger G stars rotating 3 to 5 times faster than the current Sun, the convection establishes ever stronger angular velocity contrasts between their fast equators and slow poles, and these are accompanied by prominent latitudinal temperature contrasts as well. Turning to MHD simulation of magnetic dynamo action within these younger G stars, the resulting magnetism involves wreaths of strong toroidal magnetic fields (up to 50 to 100 kG strengths) in the bulk of the convection zone, typically of opposite polarity in the northern and southern hemispheres. These fields can persist for long intervals despite being pummeled by the fast convective downflows, but they can also exhibit field reversals and cycles. Turning to shallower convective envelopes in the more luminous F-type stars that range in mass from 1.2 to 1.4 solar masses and for various rotation rates, we find that the convection can again establish solar-like differential rotation profiles with a fast equator and slow poles, but the opposite is achieved at the slower rotation rates. The F stars are also capable of building strong magnetic fields, often as wreaths, through dynamo action. We also

  11. Particle energization in 3D magnetic reconnection of relativistic pair plasmas

    SciTech Connect

    Liu Wei; Yin Lin; Albright, B. J.; Bowers, K. J.; Liang, Edison P.; Li Hui

    2011-05-15

    We present large scale 3D particle-in-cell simulations to examine particle energization in magnetic reconnection of relativistic electron-positron (pair) plasmas. The initial configuration is set up as a relativistic Harris equilibrium without a guide field. These simulations are large enough to accommodate a sufficient number of tearing and kink modes. Contrary to the non-relativistic limit, the linear tearing instability is faster than the linear kink instability, at least in our specific parameters. We find that the magnetic energy dissipation is first facilitated by the tearing instability and followed by the secondary kink instability. Particles are mostly energized inside the magnetic islands during the tearing stage due to the spatially varying electric fields produced by the outflows from reconnection. Secondary kink instability leads to additional particle acceleration. Accelerated particles are, however, observed to be thermalized quickly. The large amplitude of the vertical magnetic field resulting from the tearing modes by the secondary kink modes further help thermalizing the non-thermal particles generated from the secondary kink instability. Implications of these results for astrophysics are briefly discussed.

  12. 3-D joint inversion of the magnetotelluric phase tensor and vertical magnetic transfer functions

    NASA Astrophysics Data System (ADS)

    Tietze, Kristina; Ritter, Oliver; Egbert, Gary D.

    2015-11-01

    With advancing computational resources, 3-D inversion techniques have become feasible in recent years and are now a more widely used tool for magnetotelluric (MT) data interpretation. Galvanic distortion caused by small-scale near-surface inhomogeneities remains an obstacle for 3-D MT inversion which so far has experienced little attention. If not considered properly, the effect on 3-D inversion can be immense and result in erroneous subsurface models and interpretations. To tackle the problem we implemented inversion of the distortion-free phase tensor into the ModEM inversion package. The dimensionless phase tensor components describe only variations of the conductivity structure. When inverting these data, particular care has to be taken of the conductivity structure in the a priori model, which provides the reference frame when transferring the information from phase tensors into absolute conductivity values. Our results obtained with synthetic data show that phase tensor inversion can recover the regional conductivity structure in presence of galvanic distortion if the a priori model provides a reasonable assumption for the regional resistivity average. Joint inversion of phase tensor data and vertical magnetic transfer functions improves recovery of the absolute resistivity structure and is less dependent on the prior model. We also used phase tensor inversion for a data set of more than 250 MT sites from the central San Andreas fault, California, where a number of sites showed significant galvanic distortion. We find the regional structure of the phase tensor inversion results compatible with previously obtained models from impedance inversion. In the vicinity of distorted sites, phase tensor inversion models exhibit more homogeneous/smoother conductivity structures.

  13. Microscopic magnetic nature of K2NiF4-type 3d transition metal oxides

    NASA Astrophysics Data System (ADS)

    Sugiyama, J.; Nozaki, H.; Umegaki, I.; Higemoto, W.; Ansaldo, E. J.; Brewer, J. H.; Sakurai, H.; Kao, T.-H.; Yang, H.-D.; Månsson, M.

    2014-12-01

    In order to elucidate the magnetic nature of K2NiF4-type 3d transition metal oxides, we have measured μ+SR spectra for Sr2VO4, LaSrVO4, and Sr2CrO4 using powder samples. ZF- and wTF-μ+SR measurements propose that Sr2VO4 enters into the static antiferromagnetic (AF) order phase below 8 K. In addition, TF-μ+SR measurements evidence that the transition at 105 K is not magnetic but structural and/or electronic in origin. For LaSrVO4, static long-range order has not been observed down to 20 K, while, as T decreases from 145 K, wTF asymmetry starts to decrease below 60 K, suggesting the appearance and evolution of localized magnetic moments below 60 K. For Sr2CrO4, by contrast, both ZF- and wTF-μ+SR have confirmed the presence of antiferromagnetic order below 117 K, as predicted in the χ(T) curve.

  14. 3D Equilibrium Reconstruction with Improved Magnetic Diagnostics on the Compact Toroidal Hybrid

    NASA Astrophysics Data System (ADS)

    Ma, Xinxing; Hanson, James D.; Hartwell, Gregory J.; Knowlton, Stephen F.; Maurer, David A.

    2013-10-01

    Equilibrium reconstructions using the three-dimensional V3FIT code [ 1 ] have been performed for low density (low β) current carrying plasmas on the Compact Toroidal Hybrid (CTH), a torsatron in which the magnetic configuration can be strongly modified by an ohmically-driven plasma current. These reconstructions use 50 external magnetic diagnostic measurements, including segmented and full Rogowski coils, saddle loops, poloidal and radial magnetic pickup coils. Time dependent 3D reconstructions document the evolution of the plasma cross section and current profile, with calculated value of βθ much less than the plasma internal inductance, li. Reconstructions typically show the plasma to move outward in major radius and become less elongated in poloidal cross section with increasing plasma current. In plasmas with low vacuum transform (ιvac ~ 0 . 04), the plasma current profile peaks with li above 0 . 84 when the total transform is 1 / 2 , which typically leads disruption. With values of ιvac >= 0 . 1 , li remains low (~ 0 . 7), and the discharges no longer disrupt. This work is supported by the USDoE under grant DE-FG02-00ER54610.

  15. GMC Collisions as Triggers of Star Formation. II. 3D Turbulent, Magnetized Simulations

    NASA Astrophysics Data System (ADS)

    Wu, Benjamin; Tan, Jonathan C.; Nakamura, Fumitaka; Van Loo, Sven; Christie, Duncan; Collins, David

    2017-02-01

    We investigate giant molecular cloud collisions and their ability to induce gravitational instability and thus star formation. This mechanism may be a major driver of star formation activity in galactic disks. We carry out a series of 3D, magnetohydrodynamics (MHD), adaptive mesh refinement simulations to study how cloud collisions trigger formation of dense filaments and clumps. Heating and cooling functions are implemented based on photo-dissociation region models that span the atomic-to-molecular transition and can return detailed diagnostic information. The clouds are initialized with supersonic turbulence and a range of magnetic field strengths and orientations. Collisions at various velocities and impact parameters are investigated. Comparing and contrasting colliding and non-colliding cases, we characterize morphologies of dense gas, magnetic field structure, cloud kinematic signatures, and cloud dynamics. We present key observational diagnostics of cloud collisions, especially: relative orientations between magnetic fields and density structures, like filaments; 13CO(J = 2-1), 13CO(J = 3-2), and 12CO(J = 8-7) integrated intensity maps and spectra; and cloud virial parameters. We compare these results to observed Galactic clouds.

  16. Conceptual design of the 3D magnetic field configuration relevant to the magnetopause reconnection in the SPERF

    NASA Astrophysics Data System (ADS)

    Mao, Aohua; Ji, Hantao; Ren, Yang; E, Peng; Wang, Zhibin; Xiao, Qingmei; Xiao, Chijie

    2016-10-01

    A new terrella device, the Space Plasma Environment Research Facility (SPERF), is designed and under construction in China, with Asymmetric Reconnection EXperiment (AREX) as one component to study the interaction between the magnetosheath and magnetosphere plasmas. AREX will provide a unique platform for studying asymmetric magnetic reconnection relevant to the magnetopause, via a set of coils for simulating ``solar-wind-side'' magnetosheath field and a dipole field on the ``magnetosphere-side''. Thus it could be able to investigate a range of important issues in the magnetosphere geometry, such as the electron and ion-scale dynamics in the current sheet, particle and energy transfer from magnetosheath to magnetosphere, particle energization/heating during magnetic reconnection, 3D and asymmetric effects in fast reconnection, and so on. The plasma is generated by two flux cores at the ``magnetosheath-side'' and one electron cyclotron resonance source at the ``magnetosphere-side''. Different kinds of coils with specific current driven functions, as well as advanced diagnostics are designed. Motivation, overview of the AREX design and reconnection scenarios will be discussed.

  17. Simulation of a birdcage and a ceramic cavity HF-resonator for high magnetic fields in magnetic resonance imaging.

    PubMed

    Eriksen, E; Golombeck, M A; Junge, S; Dössel, O

    2002-01-01

    The aim of this work was the 3D-simulation of a dielectric resonator for high-field-MRI. A 12-rod-bird-cage-resonator was simulated in a first step, in order to verify the capability of the commercial simulation software MAFIA to simulate homogeneous, transversal B-fields in resonators. The second step was the simulation of frequency-independent dielectric ceramic resonators for static magnetic field strengths of 7 T and 12 T (294 MHz and 504 MHz respectively). The results were compared to the measured results of a manufactured TiO2- and a Al2O3-resonator. Only minor deviations showed up. These results led to the conclusion that dielectric resonators for high field MRI can be optimised using numerical field calculation software.

  18. Resonances in the forced turbulent wake past a 3D blunt body

    NASA Astrophysics Data System (ADS)

    Barros, Diogo; Borée, Jacques; Noack, Bernd R.; Spohn, Andreas

    2016-06-01

    We study the resonances of a forced turbulent wake past a flat-based bluff body using symmetric and antisymmetric actuation modes. The natural, unforced wake flow exhibits broadband dynamics superimposed on oscillatory motions linked to the reminiscent laminar Bénard-von Kármán instability in the turbulent flow. Harmonic and subharmonic resonances can be controlled by the phase relationship of periodic forcing and are linked to the symmetry properties of vortex shedding. Symmetric forcing leads to a strong subharmonic amplification of vortex shedding in the wake, but no harmonic excitation. The robustness of the subharmonic resonance is confirmed at different Reynolds numbers. Antisymmetric actuation, however, promotes a harmonic resonance with very similar wake and drag features.

  19. 3D Characterization of the Magnetic Signature of a Medium Sized Impact Crater at Odessa, TX

    NASA Astrophysics Data System (ADS)

    Robinson, A.; Soule, D.; Everett, M.; Rodman, T.; Mangue Ndong, M.; Pereira, A.; Platt, P.; Trahan, A.

    2008-12-01

    Meteorite impacts are a common occurrence throughout Earth's geologic history. Many of the surface expressions of large ancient impacts have been subsequently erased by weathering and erosion processes. The study of preserved meteorite impacts is necessary to better understand this natural hazard which has been increasingly linked to rapid climate change and mass extinctions. The 60 ka Odessa meteorite crater located in Ector Co. Texas, is unique because it is not only well-preserved, but also has been the subject of extensive geologic examination. Geologic mapping and numeric models indicate that the crater was caused by a relatively small oblique impactor. The crater rim is remarkably well exposed. Much of the ejecta blanket is present, although deeply eroded. There has been considerable site disturbance due to drilling, shaft excavation, trenching, construction of a museum, trails, and the oil/gas activity in surrounding fields. Two previous geophysical investigations have shown that our data clearly corresponds to large-scale thrust deformation. With this in mind we have performed 3D high resolution magnetic gradiometer surveys that will allow us to quantify and characterize the magnetic signature of small to medium impacts. We will tie this data set to a 3D photorealistic outcrop image provided by laser scanning with coarser-scale, below-ground geophysical information. Our geophysical imagery provides a useful constraint on numerical simulations of the impact and its immediate regional-scale environmental effects. This information can be used to identify impact sites whose surface expression has been erased by natural erosional processes, allowing for improved frequency estimates and improved geo-hazard assessment.

  20. Synthesis, characterization, magnetic and electrochemical properties of a new 3D hexa-copper-substituted germanotungstate

    SciTech Connect

    Li, Yanzhou; Luo, Jie; Zhang, Yanting; Zhao, Junwei; Chen, Lijuan; Ma, Pengtao; Niu, Jingyang

    2013-09-15

    An inorganic–organic hybrid hexa-copper-substituted germanotungstate Na{sub 2}[Cu(dap){sub 2}]{sub 2}[Cu(dap){sub 2}] ([Cu{sub 6}(H{sub 2}O){sub 2}(dap){sub 2}][B-α-GeW{sub 9}O{sub 34}]{sub 2})·4H{sub 2}O (1) (dap=1,2-diaminopropane) has been hydrothermally prepared and characterized by elemental analyses, inductively coupled plasma atomic emission spectrometry (ICP–AES) analyses, IR spectra, powder X-ray diffraction (PXRD), thermogravimetric analysis (TGA) and single-crystal X-ray diffraction. 1 displays the six-connected 3D network with the long topological (O′Keefe) vertex symbol is 4·4·6{sub 4}·4·4·4·4·6{sub 4}·4·4·4·6{sub 4}·4·4·4 and the short vertex (Schläfli) symbol of 4{sup 12}6{sup 3}. Magnetic measurements indicate that there are the overall ferromagnetic exchange interactions in the belt-like hexa-Cu{sup II} cluster in 1. Furthermore, the electrochemical behavior and electrocatalysis of 1 modified carbon paste electrode (1-CPE) have been studied. The reductions of nitrite, bromate and hydrogen peroxide are principally mediated by the W{sup VI}-based wave. - Graphical abstract: A hexa-Cu{sup II} sandwiched germanotungstate has been synthesized and structurally characterized. The magnetic, solid-state electrochemical and electrocatalytic properties have been investigated. Display Omitted - Highlights: • Transition-metal substituted polyoxometalates. • Hexa-copper-substituted germanotungstate. • Six-connected 3D network. • Electrocatalytic reduction of nitrite, bromate and hydrogen peroxide.

  1. The Donegal Sign Tree: A Local Legend Confirmed with Holographic Radar and 3-D Magnetics

    NASA Astrophysics Data System (ADS)

    Bechtel, T.; Cassidy, M.; Inagaki, M.; Windsor, C.; Capineri, L.; Falorni, P.; Bulleti, A.; Valentini, S.; Borgioli, G.; Ivashov, S.; Zhuravlev, A.; Razewig, V.; Vasiliev, I.; Bechtel, E.

    2009-05-01

    A tree at a crossroad in Historic Donegal, PA (founded 1722) bears unusual burls. Two are similar in size, and lie on opposite sides of the trunk at a height of six feet. Locals say that the tree engulfed an old road sign, and the geometry of the burls gives this appearance. However, the trunk between these two burls bears no welt where it sealed after swallowing the sign. In addition, there are other burls farther up the tree, which are not consistent with engulfed signs. Although the locals all know the legend of the swallowed sign, none ever actually saw the sign; not even an octogenarian who has lived at the crossroad his entire life, and recalls the tree as a child just as it is today. In order to test the veracity of the legend, this study performed subsurface imaging of the tree using holographic subsurface radar (Rascan), and 3-D measurements of the magnetic field about the tree using cesium vapor sensors. The Rascan system used is a continuous wave subsurface radar that operates at 5 discrete frequencies between 1.5 and 2.0 GHz. Reflections from subsurface objects are recorded as the phase difference pattern between an internal reference signal, and the reflected signal. Thus, it is a microwave analogy for optical holography. Rascan records reflections with two receiving antennae - parallel and perpendicular to the transmitter - so a single set of scans provides ten images; five frequencies at two polarizations. This ensures that an object at arbitrary depth will produce a strong phase difference in one of the images. As a consequence, elongate objects that are angled from the plane of scanning (e.g. a dipping sheet) produce "zebra stripes" of contrast values that vary cyclically with depth. The presence of stripes, and their relative positions in the different frequency images (the movement of which has been dubbed the "zebra shift") is useful for determining the relative depth of different portions of a dipping planar, or curved subsurface object. Rascan

  2. Polyethylenimine-interlayered core-shell-satellite 3D magnetic microspheres as versatile SERS substrates

    NASA Astrophysics Data System (ADS)

    Wang, Chongwen; Li, Ping; Wang, Junfeng; Rong, Zhen; Pang, Yuanfeng; Xu, Jiawen; Dong, Peitao; Xiao, Rui; Wang, Shengqi

    2015-11-01

    Precise fabrication of subtle nanogaps amid individual nanoparticles or between adjacent ones to obtain the highest SERS enhancement is still a challenge. Here, we reported a novel approach for fabricating core-shell-satellite 3D magnetic microspheres (CSSM), that easily form a porous 1.5 nm PEI interlayer to accommodate molecules and create sufficient hotspots between the inner Fe3O4@Ag core and outer assembled Au@Ag satellites. Experiments and finite-difference time-domain (FDTD) simulation demonstrated that the enhancement factor (EF) was about 2.03 × 108 and 6.25 × 106, respectively. In addition, the micro-scale magnetic core endowed the CSSM with a superior magnetic nature, which enabled easy separation and further enhanced Raman signals due to enrichment of targeted analytes and abundant interparticle hotspots created by magnetism-induced aggregation. Our results further demonstrated that the CSSM is expected to be a versatile SERS substrate, which has been verified by the detection of the adsorbed pesticide thiram and the non-adsorbed pesticide paraquat with a detection limit as low as 5 × 10-12 M and 1 × 10-10 M, respectively. The novel CSSM can overcome the long-standing limitations of SERS for the trace characterization of various analytes in different solutions and promises to transform SERS into a practical analytical technique.Precise fabrication of subtle nanogaps amid individual nanoparticles or between adjacent ones to obtain the highest SERS enhancement is still a challenge. Here, we reported a novel approach for fabricating core-shell-satellite 3D magnetic microspheres (CSSM), that easily form a porous 1.5 nm PEI interlayer to accommodate molecules and create sufficient hotspots between the inner Fe3O4@Ag core and outer assembled Au@Ag satellites. Experiments and finite-difference time-domain (FDTD) simulation demonstrated that the enhancement factor (EF) was about 2.03 × 108 and 6.25 × 106, respectively. In addition, the micro

  3. Wide-range nuclear magnetic resonance detector

    NASA Technical Reports Server (NTRS)

    Sturman, J. C.; Jirberg, R. J.

    1972-01-01

    Compact and easy to use solid state nuclear magnetic resonance detector is designed for measuring field strength to 20 teslas in cryogenically cooled magnets. Extremely low noise and high sensitivity make detector applicable to nearly all types of analytical nuclear magnetic resonance measurements and can be used in high temperature and radiation environments.

  4. Relativistic MHD simulations of core-collapse GRB jets: 3D instabilities and magnetic dissipation

    NASA Astrophysics Data System (ADS)

    Bromberg, Omer; Tchekhovskoy, Alexander

    2016-02-01

    Relativistic jets are associated with extreme astrophysical phenomena, like the core collapse of massive stars in gamma-ray bursts (GRBs) and the accretion on to supermassive black holes in active galactic nuclei. It is generally accepted that these jets are powered electromagnetically, by the magnetized rotation of a central compact object (black hole or neutron star). However, how the jets produce the observed emission and survive the propagation for many orders of magnitude in distance without being disrupted by current-driven instabilities is the subject of active debate. We carry out time-dependent 3D relativistic magnetohydrodynamic (MHD) simulations of relativistic, Poynting-flux-dominated jets. The jets are launched self-consistently by the rotation of a strongly magnetized central object. This determines the natural degree of azimuthal magnetic field winding, a crucial factor that controls jet stability. We find that the jets are susceptible to two types of instability: (i) a global, external kink mode that grows on long time-scales. It bodily twists the jet, reducing its propagation velocity. We show analytically that in flat density profiles, like the ones associated with galactic cores, the external mode grows and may stall the jet. In the steep profiles of stellar envelopes the external kink weakens as the jet propagates outward. (ii) a local, internal kink mode that grows over short time-scales and causes small-angle magnetic reconnection and conversion of about half of the jet electromagnetic energy flux into heat. We suggest that internal kink instability is the main dissipation mechanism responsible for powering GRB prompt emission.

  5. Nerves on magnetic resonance imaging.

    PubMed Central

    Collins, J. D.; Shaver, M. L.; Batra, P.; Brown, K.

    1989-01-01

    Nerves are often visualized on magnetic resonance imaging (MRI) studies of the soft tissues on the chest and shoulder girdle. To learn the reasons for the contrast between the nerves and adjacent tissues, the authors obtained a fresh specimen containing part of the brachial plexus nerves from the left axilla and compared MRI with x-ray projections and photomicrographs of histologic sections. The results suggest that the high signals from the nerves stand out in contrast to the low signals from their rich vascular supply. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6A Figure 6B Figure 7 PMID:2733051

  6. A remark on the Beale-Kato-Majda criterion for the 3D MHD equations with zero magnetic diffusivity

    NASA Astrophysics Data System (ADS)

    Gala, Sadek; Ragusa, Maria Alessandra

    2016-06-01

    In this work, we show that a smooth solution of the 3D MHD equations with zero magnetic diffusivity in the whole space ℝ3 breaks down if and only if a certain norm of the magnetic field blows up at the same time.

  7. Introduction to Nuclear Magnetic Resonance

    NASA Technical Reports Server (NTRS)

    Manatt, Stanley L.

    1985-01-01

    The purpose of this paper is to try to give a short overview of what the status is on nuclear magnetic resonance (NMR). It's a subject where one really has to spend some time to look at the physics in detail to develop a proper working understanding. I feel it's not appropriate to present to you density matrices, Hamiltonians of all sorts, and differential equations representing the motion of spins. I'm really going to present some history and status, and show a few very simple concepts involved in NMR. It is a form of radio frequency spectroscopy and there are a great number of nuclei that can be studied very usefully with the technique. NMR requires a magnet, a r.f. transmitter/receiver system, and a data acquisition system.

  8. Efficient Resonance Assignment of Proteins in MAS NMR by Simultaneous Intra- and Inter-residue 3D Correlation Spectroscopy

    PubMed Central

    Daviso, Eugenio; Eddy, Matthew T.; Andreas, Loren B.; Griffin, Robert G.; Herzfeld, Judith

    2013-01-01

    Resonance assignment is the first step in NMR structure determination. For magic angle spinning NMR, this is typically achieved with a set of heteronuclear correlation experiments (NCaCX, NCOCX, CONCa) that utilize SPECIFIC-CP 15N-13C transfers. However, the SPECIFIC-CP transfer efficiency is often compromised by molecular dynamics and probe performance. Here we show that one-bond ZF-TEDOR 15N-13C transfers provide simultaneous NCO and NCa transfers with at least as much sensitivity as SPECIFIC-CP for some non-crystalline samples. Furthermore, a 3D TEDOR-CC experiment provides heteronuclear sidechains correlations and robustness with respect to proton decoupling and radiofrequency power instabilities. We demonstrate transfer efficiencies and connectivities by application of 3D ZF-TEDOR-DARR to a model microcrystalline protein, GB1, and a less ideal system, GvpA in intact gas vesicles. PMID:23334347

  9. A single particle plasmon resonance study of 3D conical nanoantennas.

    PubMed

    Schäfer, Christian; Gollmer, Dominik A; Horrer, Andreas; Fulmes, Julia; Weber-Bargioni, Alexander; Cabrini, Stefano; Schuck, P James; Kern, Dieter P; Fleischer, Monika

    2013-09-07

    Metallic nanocones are well-suited optical antennas for near-field microscopy and spectroscopy, exhibiting a number of different plasmonic modes. A major challenge in using nanocones for many applications is maximizing the signal at the tip while minimizing the background from the base. It is shown that nanocone plasmon resonance properties can be shifted over a wide range of wavelengths by variation of the substrate, material, size and shape, enabling potential control over specific modes and field distributions. The individual resonances are identified and studied by correlated single particle dark field scattering and scanning electron microscopy in combination with numerical simulations.

  10. Gynecologic masses: value of magnetic resonance imaging.

    PubMed

    Hricak, H; Lacey, C; Schriock, E; Fisher, M R; Amparo, E; Dooms, G; Jaffe, R

    1985-09-01

    Forty-two women with gynecologic abnormalities were studied with the use of magnetic resonance imaging. Magnetic resonance imaging correctly assessed the origin of the pelvic mass in all patients. In the evaluation of leiomyoma, magnetic resonance imaging accurately depicted the number, size, and location of the lesion. In the evaluation of endometrial carcinoma, magnetic resonance imaging depicted the location of the lesion, the presence of cervical extension, and the depth of myometrial penetration in the majority of the cases. In the analysis of adnexal cysts, magnetic resonance imaging was sensitive in localizing the lesion and was able to distinguish serous from hemorrhagic fluid. This preliminary report indicates that magnetic resonance imaging may become a valuable imaging modality in the diagnosis of gynecologic abnormalities.

  11. Accretion to magnetized stars through the Rayleigh-Taylor instability: global 3D simulations

    NASA Astrophysics Data System (ADS)

    Kulkarni, A. K.; Romanova, M. M.

    2008-05-01

    We present results of 3D simulations of magnetohydrodynamics (MHD) instabilities at the accretion disc-magnetosphere boundary. The instability is Rayleigh-Taylor, and develops for a fairly broad range of accretion rates and stellar rotation rates and magnetic fields. It manifests itself in the form of tall, thin tongues of plasma that penetrate the magnetosphere in the equatorial plane. The shape and number of the tongues changes with time on the inner disc dynamical time-scale. In contrast with funnel flows, which deposit matter mainly in the polar region, the tongues deposit matter much closer to the stellar equator. The instability appears for relatively small misalignment angles, Θ <~ 30°, between the star's rotation and magnetic axes, and is associated with higher accretion rates. The hotspots and light curves during accretion through instability are generally much more chaotic than during stable accretion. The unstable state of accretion has possible implications for quasi-periodic oscillations and intermittent pulsations from accreting systems, as well as planet migration.

  12. Cation Exchange in Dynamic 3D Porous Magnets: Improvement of the Physical Properties.

    PubMed

    Grancha, Thais; Acosta, Alvaro; Cano, Joan; Ferrando-Soria, Jesús; Seoane, Beatriz; Gascon, Jorge; Pasán, Jorge; Armentano, Donatella; Pardo, Emilio

    2015-11-16

    We report two novel three-dimensional porous coordination polymers (PCPs) of formulas Li4{Mn4[Cu2(Me3mpba)2]3}·68H2O (2) and K4{Mn4[Cu2(Me3mpba)2]3}·69H2O (3) obtained-via alkali cation exchange in a single-crystal to single-crystal process-from the earlier reported anionic manganese(II)-copper(II) PCP of formula Na4{Mn4[Cu2(Me3mpba)2]3}·60H2O (1) [Me3mpba(4-) = N,N'-2,4,6-trimethyl-1,3-phenylenebis(oxamate)]. This postsynthetic process succeeds where the direct synthesis in solution from the corresponding building blocks fails and affords significantly more robust PCPs with enhanced magnetic properties [long-range 3D magnetic ordering temperatures for the dehydrated phases (1'-3') of 2.0 (1'), 12.0 (2'), and 20.0 K (3')]. Changes in the adsorptive properties upon postsynthetic exchange suggest that the nature, electrostatic properties, mobility, and location of the cations within the framework are crucial for the enhanced structural stability. Overall, these results further confirm the potential of postsynthetic methods (including cation exchange) to obtain PCPs with novel or enhanced physical properties while maintaining unaltered their open-framework structures.

  13. Local and Global 3-D Effects in the Magnetic Reconnection Experiment (MRX)

    NASA Astrophysics Data System (ADS)

    Dorfman, S.; Ji, H.; Yamada, M.; Oz, E.; Yoo, J.; Daughton, W.; Roytershteyn, V.

    2009-11-01

    One of the key open questions in Magnetic Reconnection is the nature of the mechanism that governs the reconnection rate in real astrophysical and laboratory systems. Comparisons between fully kinetic 2-D simulations of the Magnetic Reconnection Experiment (MRX) and experimental data show that the 2-D, collisionless expression for the electric field due to particle dynamics [1] does not match MRX data; related to this is a factor of 3-5 discrepancy in the layer width [2,3]. Adding collisions to the simulation leads to a broadening of the layer, but the level of collisionality present in MRX may not be high enough to resolve the discrepancy. Ongoing research on MRX explores the role of fluctuations and 3-D effects in the force balance. Significant toroidal asymmetries have been found, manifested by regions of high inductive electric field moving in the electron flow direction within the layer. Electromagnetic fluctuations in the lower hybrid frequency range [4] tend to occur in discharges with high local currents and a rapid local reconnection rate. The precise relation of these phenomena to fast reconnection is actively being investigated. [1] M. Hesse, et al., Phys. Plasmas, 6:1781 (1999). [2] Y. Ren, et al., Phys. Plasmas 15, 082113 (2008). [3] S. Dorfman, et al., Phys. Plasmas 15, 102107 (2008). [4] H. Ji, et al., Phys.Rev.Lett. 92 (2004) 115001. Supported by NDSEG, DOE, NASA, and NSF.

  14. Full 3-D TLM simulations of the Earth-ionosphere cavity: Effect of conductivity on the Schumann resonances

    NASA Astrophysics Data System (ADS)

    Toledo-Redondo, S.; Salinas, A.; Fornieles, J.; Portí, J.; Lichtenegger, H. I. M.

    2016-06-01

    Schumann resonances can be found in planetary atmospheres, inside the cavity formed by the conducting surface of the planet and the lower ionosphere. They are a powerful tool to investigate both the electric processes that occur in the atmosphere and the characteristics of the surface and the lower ionosphere. Results from a full 3-D model of the Earth-ionosphere electromagnetic cavity based on the Transmission-Line Modeling (TLM) method are presented. A Cartesian scheme with homogeneous cell size of 10 km is used to minimize numerical dispersion present in spherical schemes. Time and frequency domain results have been obtained to study the resonance phenomenon. The effect of conductivity on the Schumann resonances in the cavity is investigated by means of numerical simulations, studying the transition from resonant to nonresonant response and setting the conductivity limit for the resonances to develop inside the cavity. It is found that the transition from resonant to nonresonant behavior occurs for conductivity values above roughly 10-9 S/m. For large losses in the cavity, the resonances are damped, but, in addition, the peak frequencies change according to the local distance to the source and with the particular electromagnetic field component. These spatial variations present steep variations around each mode's nodal position, covering distances around 1/4 of the mode wavelength, the higher modes being more sensitive to this effect than the lower ones. The dependence of the measured frequency on the distance to the source and particular component of the electric field offers information on the source generating these resonances.

  15. Towards Single Biomolecule Imaging via Optical Nanoscale Magnetic Resonance Imaging.

    PubMed

    Boretti, Alberto; Rosa, Lorenzo; Castelletto, Stefania

    2015-09-09

    Nuclear magnetic resonance (NMR) spectroscopy is a physical marvel in which electromagnetic radiation is charged and discharged by nuclei in a magnetic field. In conventional NMR, the specific nuclei resonance frequency depends on the strength of the magnetic field and the magnetic properties of the isotope of the atoms. NMR is routinely utilized in clinical tests by converting nuclear spectroscopy in magnetic resonance imaging (MRI) and providing 3D, noninvasive biological imaging. While this technique has revolutionized biomedical science, measuring the magnetic resonance spectrum of single biomolecules is still an intangible aspiration, due to MRI resolution being limited to tens of micrometers. MRI and NMR have, however, recently greatly advanced, with many breakthroughs in nano-NMR and nano-MRI spurred by using spin sensors based on an atomic impurities in diamond. These techniques rely on magnetic dipole-dipole interactions rather than inductive detection. Here, novel nano-MRI methods based on nitrogen vacancy centers in diamond are highlighted, that provide a solution to the imaging of single biomolecules with nanoscale resolution in-vivo and in ambient conditions.

  16. Tunable Magnetic Resonance in Microwave Spintronics Devices

    NASA Technical Reports Server (NTRS)

    Chen, Yunpeng; Fan, Xin; Xie, Yungsong; Zhou, Yang; Wang, Tao; Wilson, Jeffrey D.; Simons, Rainee N.; Chui, Sui-Tat; Xiao, John Q.

    2015-01-01

    Magnetic resonance is one of the key properties of magnetic materials for the application of microwave spintronics devices. The conventional method for tuning magnetic resonance is to use an electromagnet, which provides very limited tuning range. Hence, the quest for enhancing the magnetic resonance tuning range without using an electromagnet has attracted tremendous attention. In this paper, we exploit the huge exchange coupling field between magnetic interlayers, which is on the order of 4000 Oe and also the high frequency modes of coupled oscillators to enhance the tuning range. Furthermore, we demonstrate a new scheme to control the magnetic resonance frequency. Moreover, we report a shift in the magnetic resonance frequency as high as 20 GHz in CoFe-based tunable microwave spintronics devices, which is 10X higher than conventional methods.

  17. Tunable Magnetic Resonance in Microwave Spintronics Devices

    NASA Technical Reports Server (NTRS)

    Chen, Yunpeng; Fan, Xin; Xie, Yunsong; Zhou, Yang; Wang, Tao; Wilson, Jeffrey D.; Simons, Rainee N.; Chui, Sui-Tat; Xiao, John Q.

    2015-01-01

    Magnetic resonance is one of the key properties of magnetic materials for the application of microwave spintronics devices. The conventional method for tuning magnetic resonance is to use an electromagnet, which provides very limited tuning range. Hence, the quest for enhancing the magnetic resonance tuning range without using an electromagnet has attracted tremendous attention. In this paper, we exploit the huge exchange coupling field between magnetic interlayers, which is on the order of 4000 Oe and also the high frequency modes of coupled oscillators to enhance the tuning range. Furthermore, we demonstrate a new scheme to control the magnetic resonance frequency. Moreover, we report a shift in the magnetic resonance frequency as high as 20 GHz in CoFe based tunable microwave spintronics devices, which is 10X higher than conventional methods.

  18. MAGNETIC RESONANCE ELASTOGRAPHY: A REVIEW

    PubMed Central

    Mariappan, Yogesh K; Glaser, Kevin J; Ehman, Richard L

    2011-01-01

    Magnetic Resonance Elastography (MRE) is a rapidly developing technology for quantitatively assessing the mechanical properties of tissue. The technology can be considered to be an imaging-based counterpart to palpation, commonly used by physicians to diagnose and characterize diseases. The success of palpation as a diagnostic method is based on the fact that the mechanical properties of tissues are often dramatically affected by the presence of disease processes such as cancer, inflammation, and fibrosis. MRE obtains information about the stiffness of tissue by assessing the propagation of mechanical waves through the tissue with a special magnetic resonance imaging (MRI) technique. The technique essentially involves three steps: generating shear waves in the tissue,acquiring MR images depicting the propagation of the induced shear waves andprocessing the images of the shear waves to generate quantitative maps of tissue stiffness, called elastograms. MRE is already being used clinically for the assessment of patients with chronic liver diseases and is emerging as a safe, reliable and noninvasive alternative to liver biopsy for staging hepatic fibrosis. MRE is also being investigated for application to pathologies of other organs including the brain, breast, blood vessels, heart, kidneys, lungs and skeletal muscle. The purpose of this review article is to introduce this technology to clinical anatomists and to summarize some of the current clinical applications that are being pursued. PMID:20544947

  19. Properties of the prominence magnetic field and plasma distributions as obtained from 3D whole-prominence fine structure modeling

    NASA Astrophysics Data System (ADS)

    Gunár, S.; Mackay, D. H.

    2016-07-01

    Aims: We analyze distributions of the magnetic field strength and prominence plasma (temperature, pressure, plasma β, and mass) using the 3D whole-prominence fine structure model. Methods: The model combines a 3D magnetic field configuration of an entire prominence, obtained from non-linear force-free field simulations, with a detailed semi-empirically derived description of the prominence plasma. The plasma is located in magnetic dips in hydrostatic equilibrium and is distributed along multiple fine structures within the 3D magnetic model. Results: We show that in the modeled prominence, the variations of the magnetic field strength and its orientation are insignificant on scales comparable to the smallest dimensions of the observed prominence fine structures. We also show the ability of the 3D whole-prominence fine structure model to reveal the distribution of the prominence plasma with respect to its temperature within the prominence volume. This provides new insights into the composition of the prominence-corona transition region. We further demonstrate that the values of the plasma β are small throughout the majority of the modeled prominences when realistic photospheric magnetic flux distributions and prominence plasma parameters are assumed. While this is generally true, we also find that in the region with the deepest magnetic dips, the plasma β may increase towards unity. Finally, we show that the mass of the modeled prominence plasma is in good agreement with the mass of observed non-eruptive prominences.

  20. Electronic structure and local magnetism of 3d-5d impurity substituted CeFe2

    NASA Astrophysics Data System (ADS)

    Das, Rakesh; Das, G. P.; Srivastava, S. K.

    2016-04-01

    We present here a systematic first-principles study of electronic structure and local magnetic properties of Ce[Fe0.75M0.25]2 compounds, where M is a 3d, 4d or 5d transition or post-transition element, using the generalized gradient approximation of the density functional theory. The d-f band hybridizations existing in CeFe2 get modified by the impurity M in an orderly manner across a period for each impurity series: the hybridization is strongest for the Mn group impurity in the period and gets diminished on either side of it. The weakening of the d-f hybridization strength is also associated with a relative localization of the Ce 4f states with respect to the delocalized 4f states in CeFe2. The above effects are most prominent for 3d impurity series, while for 4d and 5d impurities, the hybridizations and relocalizations are relatively weak due primarily to the relatively extended nature of 4d and 5d wavefunctions. The Ce local moment is found to decrease from the CeFe2 value in proportion to the strength of relocalization, thus following almost the same orderly trend as obeyed by the d-f hybridization. Further, depending on the way the spin-up and spin-down densities of states of an impurity shift relative to the Fermi energy, the impurity local moments are highest for Mn or Fe group, reduce on either side, become zero for Ni to Ga, and are small but negative for V and Ti. The Ce hyperfine field is found to follow the M local moment in a linear fashion, and vice-versa.

  1. 3D carotid plaque MR Imaging

    PubMed Central

    Parker, Dennis L.

    2015-01-01

    SYNOPSIS There has been significant progress made in 3D carotid plaque magnetic resonance imaging techniques in recent years. 3D plaque imaging clearly represents the future in clinical use. With effective flow suppression techniques, choices of different contrast weighting acquisitions, and time-efficient imaging approaches, 3D plaque imaging offers flexible imaging plane and view angle analysis, large coverage, multi-vascular beds capability, and even can be used in fast screening. PMID:26610656

  2. Magnetic field induced controllable self-assembly of maghemite nanocrystals: From 3D arrays to 1D nanochains

    NASA Astrophysics Data System (ADS)

    Tang, Yan; Chen, Qianwang; Chen, Rongsheng

    2015-08-01

    A hydrothermal process has been used to synthesize walnut-like maghemite superstructures which can be further self-assembled in a controllable manner into ordered three-dimensional (3D) architectures and one-dimensional (1D) nanochains in the presence of different external magnetic field. The assembly behavior of the maghemite nanoparticles isclosely related to the van der Waals interactions and external-field-induced magnetic dipole interactions. The magnetic properties of these nanostructures are also investigated.

  3. Registration and real-time visualization of transcranial magnetic stimulation with 3-D MR images.

    PubMed

    Noirhomme, Quentin; Ferrant, Matthieu; Vandermeeren, Yves; Olivier, Etienne; Macq, Benoît; Cuisenaire, Olivier

    2004-11-01

    This paper describes a method for registering and visualizing in real-time the results of transcranial magnetic stimulations (TMS) in physical space on the corresponding anatomical locations in MR images of the brain. The method proceeds in three main steps. First, the patient scalp is digitized in physical space with a magnetic-field digitizer, following a specific digitization pattern. Second, a registration process minimizes the mean square distance between those points and a segmented scalp surface extracted from the magnetic resonance image. Following this registration, the physician can follow the change in coil position in real-time through the visualization interface and adjust the coil position to the desired anatomical location. Third, amplitude of motor evoked potentials can be projected onto the segmented brain in order to create functional brain maps. The registration has subpixel accuracy in a study with simulated data, while we obtain a point to surface root-mean-square error of 1.17+/-0.38 mm in a 24 subject study.

  4. Advances in mechanical detection of magnetic resonance

    PubMed Central

    Kuehn, Seppe; Hickman, Steven A.; Marohn, John A.

    2008-01-01

    The invention and initial demonstration of magnetic resonance force microscopy (MRFM) in the early 1990s launched a renaissance of mechanical approaches to detecting magnetic resonance. This article reviews progress made in MRFM in the last decade, including the demonstration of scanned probe detection of magnetic resonance (electron spin resonance, ferromagnetic resonance, and nuclear magnetic resonance) and the mechanical detection of electron spin resonance from a single spin. Force and force-gradient approaches to mechanical detection are reviewed and recent related work using attonewton sensitivity cantilevers to probe minute fluctuating electric fields near surfaces is discussed. Given recent progress, pushing MRFM to single proton sensitivity remains an exciting possibility. We will survey some practical and fundamental issues that must be resolved to meet this challenge. PMID:18266413

  5. Torque-mixing magnetic resonance spectroscopy.

    PubMed

    Losby, J E; Fani Sani, F; Grandmont, D T; Diao, Z; Belov, M; Burgess, J A J; Compton, S R; Hiebert, W K; Vick, D; Mohammad, K; Salimi, E; Bridges, G E; Thomson, D J; Freeman, M R

    2015-11-13

    A universal, torque-mixing method for magnetic resonance spectroscopy is presented. In analogy to resonance detection by magnetic induction, the transverse component of a precessing dipole moment can be measured in sensitive broadband spectroscopy, here using a resonant mechanical torque sensor. Unlike induction, the torque amplitude allows equilibrium magnetic properties to be monitored simultaneously with the spin dynamics. Comprehensive electron spin resonance spectra of a single-crystal, mesoscopic yttrium iron garnet disk at room temperature reveal assisted switching between magnetization states and mode-dependent spin resonance interactions with nanoscale surface imperfections. The rich detail allows analysis of even complex three-dimensional spin textures. The flexibility of microelectromechanical and optomechanical devices combined with broad generality and capabilities of torque-mixing magnetic resonance spectroscopy offers great opportunities for development of integrated devices.

  6. Ising-like chain magnetism, Arrhenius magnetic relaxation, and case against 3D magnetic ordering in β-manganese phthalocyanine (C32H16MnN8)

    NASA Astrophysics Data System (ADS)

    Wang, Zhengjun; Seehra, Mohindar S.

    2016-04-01

    Previous magnetic studies in the organic semiconductor β-manganese phthalocyanine (β-MnPc) have reported it to be a canted ferromagnet below T C  ≈  8.6 K. However, the recent result of the lack of a λ-type anomaly in the specific heat versus temperature data near the quoted T C has questioned the presence of long-range 3-dimensional (3D) magnetic ordering in this system. In this paper, detailed measurements and analysis of the temperature (2 K-300 K) and magnetic field (up to 90 kOe) dependence of the dc and ac magnetic susceptibilities in a powder sample of β-MnPc leads us to conclude that 3D long-range magnetic ordering is absent in this material. This is supported by the Arrott plots and the lack of a peak in the ac susceptibilities, χ‧ and χ″, near the quoted T C. Instead, the system can be best described as an Ising-like chain magnet with Arrhenius relaxation of the magnetization governed by an intra-layer ferromagnetic exchange constant J/k B  =  2.6 K and the single ion anisotropy energy parameter |D|/k B  =  8.3 K. The absence of 3D long range order is consistent with the measured \\mid D\\mid   >  J.

  7. Connecting Global Measures of 3D Magnetic Reconnection to Local Kinetic Physics

    SciTech Connect

    Daughton, William Scott

    2015-07-16

    After giving the motivation for the work, slides present the topic under the following headings: Description of LAPD experiment; Actual simulation setup; Simple kinetic theory of ined-tied tearing; Diagnostics to characterizing 3D reconnection; Example #1 - short-tied system; and Example #2 - long line-tied system. Colorful simulations are shown for quasipotential vs field line exponentiation, field line integrated Ohms Law, and correlation with agyrotopy & energy conversion for example #1; and evolution of current density for largest case, field exponentiation vs quasi-potential, and time evolution of magnetic field lines for example #2. To satisfy line-tied boundary conditions, there is need for superposition of oblique modes--the simple two-mode approximation works surprisingly well. For force-free layers with bg >1, the fastest growing periodic modes are oblique with kxλ ~0.5. This implies a minimum length of Ly > 2πλbg. There are strong correlations between σ → Ξ → A0e (observable with spacecraft). Electron pressure tensor is the dominant non-ideal term.

  8. Synthesis, characterization, magnetic and electrochemical properties of a new 3D hexa-copper-substituted germanotungstate

    NASA Astrophysics Data System (ADS)

    Li, Yanzhou; Luo, Jie; Zhang, Yanting; Zhao, Junwei; Chen, Lijuan; Ma, Pengtao; Niu, Jingyang

    2013-09-01

    An inorganic-organic hybrid hexa-copper-substituted germanotungstate Na2[Cu(dap)2]2[Cu(dap)2] {[Cu6(H2O)2(dap)2][B-α-GeW9O34]2}·4H2O (1) (dap=1,2-diaminopropane) has been hydrothermally prepared and characterized by elemental analyses, inductively coupled plasma atomic emission spectrometry (ICP-AES) analyses, IR spectra, powder X-ray diffraction (PXRD), thermogravimetric analysis (TGA) and single-crystal X-ray diffraction. 1 displays the six-connected 3D network with the long topological (O'Keefe) vertex symbol is 4·4·64·4·4·4·4·64·4·4·4·64·4·4·4 and the short vertex (Schläfli) symbol of 41263. Magnetic measurements indicate that there are the overall ferromagnetic exchange interactions in the belt-like hexa-CuII cluster in 1. Furthermore, the electrochemical behavior and electrocatalysis of 1 modified carbon paste electrode (1-CPE) have been studied. The reductions of nitrite, bromate and hydrogen peroxide are principally mediated by the WVI-based wave.

  9. Magnetic Resonance Imaging of Electrolysis.

    NASA Astrophysics Data System (ADS)

    Meir, Arie; Hjouj, Mohammad; Rubinsky, Liel; Rubinsky, Boris

    2015-02-01

    This study explores the hypothesis that Magnetic Resonance Imaging (MRI) can image the process of electrolysis by detecting pH fronts. The study has relevance to real time control of cell ablation with electrolysis. To investigate the hypothesis we compare the following MR imaging sequences: T1 weighted, T2 weighted and Proton Density (PD), with optical images acquired using pH-sensitive dyes embedded in a physiological saline agar solution phantom treated with electrolysis and discrete measurements with a pH microprobe. We further demonstrate the biological relevance of our work using a bacterial E. Coli model, grown on the phantom. The results demonstrate the ability of MRI to image electrolysis produced pH changes in a physiological saline phantom and show that these changes correlate with cell death in the E. Coli model grown on the phantom. The results are promising and invite further experimental research.

  10. Functional Magnetic Resonance Imaging Methods

    PubMed Central

    Chen, Jingyuan E.; Glover, Gary H.

    2015-01-01

    Since its inception in 1992, Functional Magnetic Resonance Imaging (fMRI) has become an indispensible tool for studying cognition in both the healthy and dysfunctional brain. FMRI monitors changes in the oxygenation of brain tissue resulting from altered metabolism consequent to a task-based evoked neural response or from spontaneous fluctuations in neural activity in the absence of conscious mentation (the “resting state”). Task-based studies have revealed neural correlates of a large number of important cognitive processes, while fMRI studies performed in the resting state have demonstrated brain-wide networks that result from brain regions with synchronized, apparently spontaneous activity. In this article, we review the methods used to acquire and analyze fMRI signals. PMID:26248581

  11. Magnetic Resonance Elastography of Abdomen

    PubMed Central

    Venkatesh, Sudhakar K.; Ehman, Richard L.

    2015-01-01

    Many diseases cause substantial changes in the mechanical properties of tissue and this provides motivation for developing methods to non-invasively assess the stiffness of tissue using imaging technology. Magnetic resonance elastography (MRE) has emerged as a versatile MRI-based technique, based on direct visualization of propagating shear waves in the tissues. The most established clinical application of MRE in the abdomen is in chronic liver disease. MRE is currently regarded as the most accurate non-invasive technique for detection and staging of liver fibrosis. Increasing experience and ongoing research is leading to exploration of applications in other abdominal organs. In this review article, the current use of MRE in liver disease and the potential future applications of this technology in other parts of the abdomen are surveyed. PMID:25488346

  12. Microcoil nuclear magnetic resonance spectroscopy.

    PubMed

    Webb, A G

    2005-08-10

    In comparison with most analytical chemistry techniques, nuclear magnetic resonance has an intrinsically low sensitivity, and many potential applications are therefore precluded by the limited available quantity of certain types of sample. In recent years, there has been a trend, both commercial and academic, towards miniaturization of the receiver coil in order to increase the mass sensitivity of NMR measurements. These small coils have also proved very useful in coupling NMR detection with commonly used microseparation techniques. A further development enabled by small detectors is parallel data acquisition from many samples simultaneously, made possible by incorporating multiple receiver coils into a single NMR probehead. This review article summarizes recent developments and applications of "microcoil" NMR spectroscopy.

  13. Chemical Principles Revisited. Proton Magnetic Resonance Spectroscopy.

    ERIC Educational Resources Information Center

    McQuarrie, Donald A.

    1988-01-01

    Discusses how to interpret nuclear magnetic resonance (NMR) spectra and how to use them to determine molecular structures. This discussion is limited to spectra that are a result of observation of only the protons in a molecule. This type is called proton magnetic resonance (PMR) spectra. (CW)

  14. Magnetic resonance imaging of radiation optic neuropathy

    SciTech Connect

    Zimmerman, C.F.; Schatz, N.J.; Glaser, J.S. )

    1990-10-15

    Three patients with delayed radiation optic neuropathy after radiation therapy for parasellar neoplasms underwent magnetic resonance imaging. The affected optic nerves and chiasms showed enlargement and focal gadopentetate dimeglumine enhancement. The magnetic resonance imaging technique effectively detected and defined anterior visual pathway changes of radionecrosis and excluded the clinical possibility of visual loss because of tumor recurrence.

  15. Magnetic resonance sees lesions of multiple sclerosis

    SciTech Connect

    Ziporyn, T.

    1985-02-15

    The value of nuclear magnetic resonance imaging in the diagnosis and quantitation of the progression of multiple sclerosis is discussed. Magnetic resonance imaging generates images that reflect differential density and velocity of hydrogen nuclei between cerebral gray and white matter, as well as between white matter and pathological lesions of the disease.

  16. Functional Magnetic Resonance Imaging and Pediatric Anxiety

    ERIC Educational Resources Information Center

    Pine, Daniel S.; Guyer, Amanda E.; Leibenluft, Ellen; Peterson, Bradley S.; Gerber, Andrew

    2008-01-01

    The use of functional magnetic resonance imaging in investigating pediatric anxiety disorders is studied. Functional magnetic resonance imaging can be utilized in demonstrating parallels between the neural architecture of difference in anxiety of humans and the neural architecture of attention-orienting behavior in nonhuman primates or rodents.…

  17. Mitigation of Alfvenic activity by 3D magnetic perturbations on NSTX

    SciTech Connect

    Kramer, G. J.; Bortolon, A.; Ferraro, N. M.; Spong, D. A.; Crocker, N. A.; Darrow, D. S.; Fredrickson, E. D.; Kubota, S.; Park, J. -K.; Podesta, M.; Heidbrink, W. W.

    2016-07-05

    Observations on the National Spherical Torus eXperiment (NSTX) indicate that externally applied non-axisymmetric magnetic perturbations (MP) can reduce the amplitude of Toroidal Alfven Eigenmodes (TAE) and Global Alfven Eigenmodes (GAE) in response to pulsed n=3 non-resonant fields. From full-orbit following Monte Carlo simulations with the 1- and 2-fluid resistive MHD plasma response to the magnetic perturbation included, it was found that in response to MP pulses the fast-ion losses increased and the fast-ion drive for the GAEs was reduced. The MP did not affect the fast-ion drive for the TAEs significantly but the Alfven continuum at the plasma edge was found to be altered due to the toroidal symmetry breaking which leads to coupling of different toroidal harmonics. The TAE gap was reduced at the edge creating enhanced continuum damping of the global TAEs, which is consistent with the observations. Furthermore, the results suggest that optimized non-axisymmetric MP might be exploited to control and mitigate Alfven instabilities by tailoring the fast-ion distribution function and/or continuum structure.

  18. Mitigation of Alfvenic activity by 3D magnetic perturbations on NSTX

    DOE PAGES

    Kramer, G. J.; Bortolon, A.; Ferraro, N. M.; ...

    2016-07-05

    Observations on the National Spherical Torus eXperiment (NSTX) indicate that externally applied non-axisymmetric magnetic perturbations (MP) can reduce the amplitude of Toroidal Alfven Eigenmodes (TAE) and Global Alfven Eigenmodes (GAE) in response to pulsed n=3 non-resonant fields. From full-orbit following Monte Carlo simulations with the 1- and 2-fluid resistive MHD plasma response to the magnetic perturbation included, it was found that in response to MP pulses the fast-ion losses increased and the fast-ion drive for the GAEs was reduced. The MP did not affect the fast-ion drive for the TAEs significantly but the Alfven continuum at the plasma edge wasmore » found to be altered due to the toroidal symmetry breaking which leads to coupling of different toroidal harmonics. The TAE gap was reduced at the edge creating enhanced continuum damping of the global TAEs, which is consistent with the observations. Furthermore, the results suggest that optimized non-axisymmetric MP might be exploited to control and mitigate Alfven instabilities by tailoring the fast-ion distribution function and/or continuum structure.« less

  19. Mitigation of Alfvénic activity by 3D magnetic perturbations on NSTX

    NASA Astrophysics Data System (ADS)

    Kramer, G. J.; Bortolon, A.; Ferraro, N. M.; Spong, D. A.; Crocker, N. A.; Darrow, D. S.; Fredrickson, E. D.; Kubota, S.; Park, J.-K.; Podestà, M.; Heidbrink, W. W.; the NSTX Team

    2016-08-01

    Observations on the National Spherical Torus Experiment (NSTX) indicate that externally applied non-axisymmetric magnetic perturbations (MP) can reduce the amplitude of toroidal Alfvén eigenmodes (TAE) and global Alfvén eigenmodes (GAE) in response to pulsed n  =  3 non-resonant fields. From full-orbit following Monte Carlo simulations with the one- and two-fluid resistive MHD plasma response to the magnetic perturbation included, it was found that in response to MP pulses the fast-ion losses increased and the fast-ion drive for the GAEs was reduced. The MP did not affect the fast-ion drive for the TAEs significantly but the Alfvén continuum at the plasma edge was found to be altered due to the toroidal symmetry breaking which leads to coupling of different toroidal harmonics. The TAE gap was reduced at the edge creating enhanced continuum damping of the global TAEs, which is consistent with the observations. The results suggest that optimized non-axisymmetric MP might be exploited to control and mitigate Alfvén instabilities by tailoring the fast-ion distribution function and/or continuum structure.

  20. Modelling of plasma response to 3D external magnetic field perturbations in EAST

    NASA Astrophysics Data System (ADS)

    Yang, Xu; Sun, Youwen; Liu, Yueqiang; Gu, Shuai; Liu, Yue; Wang, Huihui; Zhou, Lina; Guo, Wenfeng

    2016-11-01

    Sustained mitigation and/or suppression of type-I edge localized modes (ELMs) has been achieved in EAST high-confinement plasmas, utilizing the resonant magnetic perturbation (RMP) fields produced by two rows of magnetic coils located just inside the vacuum vessel. Systematic toroidal modelling of the plasma response to these RMP fields with various coil configurations (with dominant toroidal mode number n  = 1, 2, 3, 4) in EAST is, for the first time, carried out by using the MARS-F code (Liu et al 2000 Phys. Plasmas 7 3681), with results reported here. In particular, the plasma response is computed with varying coil phasing (the toroidal phase difference of the coil currents) between the upper and lower rows of coils, from 0 to 360°. Four figures of merit, constructed based on the MARS-F computations, are used to determine the optimal coil phasing. The modelled results, taking into account the plasma response, agree well with the experimental observations in terms of the coil phasing for both the mitigated and the suppressed ELM cases in EAST experiments. This study provides a crucial confirmation of the role of the plasma edge peeling response in ELM control, complementing similar studies carried out for other tokamak devices.

  1. Synthesis and Application of Novel 3D Magnetic Chlorogenic Acid Imprinted Polymers Based on a Graphene-Carbon Nanotube Composite.

    PubMed

    Yan, Liang; Yin, Yuli; Lv, Piaopiao; Zhang, Zhaohui; Wang, Jing; Long, Fang

    2016-04-20

    A novel three-dimensional (3D) magnetic chlorogenic acid (CGA) imprinted polymer (MMIP) was prepared with novel carbon hybrid nanocomposite as the carrier, chlorogenic acid as the template molecule, and methacrylic acid as the functional monomer. The 3D MMIPs were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, vibrating sample magnetometer, and UV spectrometry in detail. The results showed that the imprinted layer was attached successfully on the surface of a 3D magnetic carbon hybrid nanocomposite. The adsorption performance of the 3D MMIPs was investigated, and the results showed that the 3D MMIPs exhibited high adsorption capacity and fast adsorption rate toward CGA with a maximum adsorption capacity of 10.88 mg g(-1). The extraction conditions involving washing solvent, the pH of eluent solvent, elution volume, and desorption time were also investigated in detail. Combined with high-performance liquid chromatography, the 3D MMIPs have been applied to successfully extract CGA from Eucommia leaf extract samples.

  2. Magnetic resonance imaging of the temporomandibular joint.

    PubMed

    Hayt, M W; Abrahams, J J; Blair, J

    2000-04-01

    The spectrum of disease that affects the temporomandibular joint (TMJ) can be varied. To differentiate among the diseases that cause pain and dysfunction, an intimate knowledge of the anatomy, physiology, and pathology of this region is necessary. Due to the joint's complex anatomy and relationship to the skin, it has been difficult to image in the past. Magnetic resonance imaging is ideally suited for visualizing TMJ because of its superb contrast resolution when imaging soft tissues. Magnetic resonance imaging allows simultaneous bilateral visualization of both joints. The ability to noninvasively resolve anatomic detail can be performed easily and quickly using magnetic resonance imaging. The development of magnetic resonance imaging has greatly aided the diagnosis of TMJ disorders. An understanding of TMJ anatomy and pathogenesis of TMJ pain is crucial for interpretation of magnetic resonance imaging and subsequent treatment.

  3. Multidimensionally encoded magnetic resonance imaging.

    PubMed

    Lin, Fa-Hsuan

    2013-07-01

    Magnetic resonance imaging (MRI) typically achieves spatial encoding by measuring the projection of a q-dimensional object over q-dimensional spatial bases created by linear spatial encoding magnetic fields (SEMs). Recently, imaging strategies using nonlinear SEMs have demonstrated potential advantages for reconstructing images with higher spatiotemporal resolution and reducing peripheral nerve stimulation. In practice, nonlinear SEMs and linear SEMs can be used jointly to further improve the image reconstruction performance. Here, we propose the multidimensionally encoded (MDE) MRI to map a q-dimensional object onto a p-dimensional encoding space where p > q. MDE MRI is a theoretical framework linking imaging strategies using linear and nonlinear SEMs. Using a system of eight surface SEM coils with an eight-channel radiofrequency coil array, we demonstrate the five-dimensional MDE MRI for a two-dimensional object as a further generalization of PatLoc imaging and O-space imaging. We also present a method of optimizing spatial bases in MDE MRI. Results show that MDE MRI with a higher dimensional encoding space can reconstruct images more efficiently and with a smaller reconstruction error when the k-space sampling distribution and the number of samples are controlled.

  4. ORBXYZ: a 3D single-particle orbit code for following charged-particle trajectories in equilibrium magnetic fields

    SciTech Connect

    Anderson, D.V.; Cohen, R.H.; Ferguson, J.R.; Johnston, B.M.; Sharp, C.B.; Willmann, P.A.

    1981-06-30

    The single particle orbit code, TIBRO, has been modified extensively to improve the interpolation methods used and to allow use of vector potential fields in the simulation of charged particle orbits on a 3D domain. A 3D cubic B-spline algorithm is used to generate spline coefficients used in the interpolation. Smooth and accurate field representations are obtained. When vector potential fields are used, the 3D cubic spline interpolation formula analytically generates the magnetic field used to push the particles. This field has del.BETA = 0 to computer roundoff. When magnetic induction is used the interpolation allows del.BETA does not equal 0, which can lead to significant nonphysical results. Presently the code assumes quadrupole symmetry, but this is not an essential feature of the code and could be easily removed for other applications. Many details pertaining to this code are given on microfiche accompanying this report.

  5. ORBXYZ: A 3D single-particle orbit code for following charged particle trajectories in equilibrium magnetic fields

    NASA Astrophysics Data System (ADS)

    Anderson, D. V.; Cohen, R. H.; Ferguson, J. R.; Johnston, B. M.; Sharp, C. B.; Willmann, P. A.

    1981-06-01

    The single particle orbit code, TIBRO, was modified extensively to improve the interpolation methods used and to allow use of vector potential fields in the simulation of charged particle orbits on a 3D domain. A 3D cubic B-spline algorithm is used to generate spline coefficients used in the interpolation. Smooth and accurate field representations are obtained. When vector potential fields are used, the 3D cubic spline interpolation formula analytically generates the magnetic field used to push the particles. This field has del.BETA = 0 to computer roundoff. When magnetic induction is used the interpolation allows del.BETA does not equal 0, which can lead to significant nonphysical results. Presently the code assumes quadrupole symmetry, but this is not an essential feature of the code and could be easily removed for other applications.

  6. Magnetic Resonance Imaging (MRI): Lumbar Spine (For Parents)

    MedlinePlus

    ... If You Have Questions en español Resonancia magnética: columna lumbar What It Is Magnetic resonance imaging (MRI) ... MORE ON THIS TOPIC Magnetic Resonance Imaging (MRI): Cervical Spine Lumbar Puncture (Spinal Tap) Magnetic Resonance Imaging ( ...

  7. A low feed-through 3D vacuum packaging technique with silicon vias for RF MEMS resonators

    NASA Astrophysics Data System (ADS)

    Zhao, Jicong; Yuan, Quan; Kan, Xiao; Yang, Jinling; Yang, Fuhua

    2017-01-01

    This paper presents a wafer-level three-dimensional (3D) vacuum packaging technique for radio frequency microelectromechanical systems (RF MEMS) resonators. A Sn-rich Au-Sn solder bonding is employed to provide a vacuum encapsulation as well as electrical conductions. Vertical silicon vias are micro-fabricated by glass reflow process. The optimized grounding, via pitch, and all-round shielding effectively reduce feed-through capacitance. Thus the signal-to-background ratios (SBRs) of the transmission signals increase from 17 dB to 20 dB, and the quality factor (Q) values of the packaged resonators go from around 8000 up to more than 9500. The measured average leak rate and shear strength are (2.55  ±  0.9)  ×  10-8 atm-cc s-1 and 42.53  ±  4.19 MPa, respectively. Furthermore, thermal cycling test between  -40 °C and 100 °C and high temperature storage test at 150 °C show that the resonant-frequency drifts are less than  ±7 ppm. In addition, the SBRs and the Q values have no obvious change after the tests. The experimental results demonstrated that the proposed encapsulation technique is well suited for the applications of RF MEMS devices.

  8. Compression-sensitive magnetic resonance elastography

    NASA Astrophysics Data System (ADS)

    Hirsch, Sebastian; Beyer, Frauke; Guo, Jing; Papazoglou, Sebastian; Tzschaetzsch, Heiko; Braun, Juergen; Sack, Ingolf

    2013-08-01

    Magnetic resonance elastography (MRE) quantifies the shear modulus of biological tissue to detect disease. Complementary to the shear elastic properties of tissue, the compression modulus may be a clinically useful biomarker because it is sensitive to tissue pressure and poromechanical interactions. In this work, we analyze the capability of MRE to measure volumetric strain and the dynamic bulk modulus (P-wave modulus) at a harmonic drive frequency commonly used in shear-wave-based MRE. Gel phantoms with various densities were created by introducing CO2-filled cavities to establish a compressible effective medium. The dependence of the effective medium's bulk modulus on phantom density was investigated via static compression tests, which confirmed theoretical predictions. The P-wave modulus of three compressible phantoms was calculated from volumetric strain measured by 3D wave-field MRE at 50 Hz drive frequency. The results demonstrate the MRE-derived volumetric strain and P-wave modulus to be sensitive to the compression properties of effective media. Since the reconstruction of the P-wave modulus requires third-order derivatives, noise remains critical, and P-wave moduli are systematically underestimated. Focusing on relative changes in the effective bulk modulus of tissue, compression-sensitive MRE may be useful for the noninvasive detection of diseases involving pathological pressure alterations such as hepatic hypertension or hydrocephalus.

  9. Magnetic resonance imaging for characterizing myocardial diseases.

    PubMed

    Saeed, Maythem; Liu, Hui; Liang, Chang-Hong; Wilson, Mark W

    2017-03-31

    The National Institute of Health defined cardiomyopathy as diseases of the heart muscle. These myocardial diseases have different etiology, structure and treatment. This review highlights the key imaging features of different myocardial diseases. It provides information on myocardial structure/orientation, perfusion, function and viability in diseases related to cardiomyopathy. The standard cardiac magnetic resonance imaging (MRI) sequences can reveal insight on left ventricular (LV) mass, volumes and regional contractile function in all types of cardiomyopathy diseases. Contrast enhanced MRI sequences allow visualization of different infarct patterns and sizes. Enhancement of myocardial inflammation and infarct (location, transmurality and pattern) on contrast enhanced MRI have been used to highlight the key differences in myocardial diseases, predict recovery of function and healing. The common feature in many forms of cardiomyopathy is the presence of diffuse-fibrosis. Currently, imaging sequences generating the most interest in cardiomyopathy include myocardial strain analysis, tissue mapping (T1, T2, T2*) and extracellular volume (ECV) estimation techniques. MRI sequences have the potential to decode the etiology by showing various patterns of infarct and diffuse fibrosis in myocarditis, amyloidosis, sarcoidosis, hypertrophic cardiomyopathy due to aortic stenosis, restrictive cardiomyopathy, arrythmogenic right ventricular dysplasia and hypertension. Integrated PET/MRI system may add in the future more information for the diagnosis and progression of cardiomyopathy diseases. With the promise of high spatial/temporal resolution and 3D coverage, MRI will be an indispensible tool in diagnosis and monitoring the benefits of new therapies designed to treat myocardial diseases.

  10. Segmentation of neuroanatomy in magnetic resonance images

    NASA Astrophysics Data System (ADS)

    Simmons, Andrew; Arridge, Simon R.; Barker, G. J.; Tofts, Paul S.

    1992-06-01

    Segmentation in neurological magnetic resonance imaging (MRI) is necessary for feature extraction, volume measurement and for the three-dimensional display of neuroanatomy. Automated and semi-automated methods offer considerable advantages over manual methods because of their lack of subjectivity, their data reduction capabilities, and the time savings they give. We have used dual echo multi-slice spin-echo data sets which take advantage of the intrinsically multispectral nature of MRI. As a pre-processing step, a rf non-uniformity correction is applied and if the data is noisy the images are smoothed using a non-isotropic blurring method. Edge-based processing is used to identify the skin (the major outer contour) and the eyes. Edge-focusing has been used to significantly simplify edge images and thus allow simple postprocessing to pick out the brain contour in each slice of the data set. Edge- focusing is a technique which locates significant edges using a high degree of smoothing at a coarse level and tracks these edges to a fine level where the edges can be determined with high positional accuracy. Both 2-D and 3-D edge-detection methods have been compared. Once isolated, the brain is further processed to identify CSF, and, depending upon the MR pulse sequence used, the brain itself may be sub-divided into gray matter and white matter using semi-automatic contrast enhancement and clustering methods.

  11. A new approach for magnetic curves in 3D Riemannian manifolds

    SciTech Connect

    Bozkurt, Zehra Gök, Ismail Yaylı, Yusuf Ekmekci, F. Nejat

    2014-05-15

    A magnetic field is defined by the property that its divergence is zero in a three-dimensional oriented Riemannian manifold. Each magnetic field generates a magnetic flow whose trajectories are curves called as magnetic curves. In this paper, we give a new variational approach to study the magnetic flow associated with the Killing magnetic field in a three-dimensional oriented Riemann manifold, (M{sup 3}, g). And then, we investigate the trajectories of the magnetic fields called as N-magnetic and B-magnetic curves.

  12. Stepped impedance resonators for high-field magnetic resonance imaging.

    PubMed

    Akgun, Can E; DelaBarre, Lance; Yoo, Hyoungsuk; Sohn, Sung-Min; Snyder, Carl J; Adriany, Gregor; Ugurbil, Kamil; Gopinath, Anand; Vaughan, J Thomas

    2014-02-01

    Multi-element volume radio-frequency (RF) coils are an integral aspect of the growing field of high-field magnetic resonance imaging. In these systems, a popular volume coil of choice has become the transverse electromagnetic (TEM) transceiver coil consisting of microstrip resonators. In this paper, to further advance this design approach, a new microstrip resonator strategy in which the transmission line is segmented into alternating impedance sections, referred to as stepped impedance resonators (SIRs), is investigated. Single-element simulation results in free space and in a phantom at 7 T (298 MHz) demonstrate the rationale and feasibility of the SIR design strategy. Simulation and image results at 7 T in a phantom and human head illustrate the improvements in a transmit magnetic field, as well as RF efficiency (transmit magnetic field versus specific absorption rate) when two different SIR designs are incorporated in 8-element volume coil configurations and compared to a volume coil consisting of microstrip elements.

  13. Stepped Impedance Resonators for High Field Magnetic Resonance Imaging

    PubMed Central

    Akgun, Can E.; DelaBarre, Lance; Yoo, Hyoungsuk; Sohn, Sung-Min; Snyder, Carl J.; Adriany, Gregor; Ugurbil, Kamil; Gopinath, Anand; Vaughan, J. Thomas

    2014-01-01

    Multi-element volume radio-frequency (RF) coils are an integral aspect of the growing field of high field magnetic resonance imaging (MRI). In these systems, a popular volume coil of choice has become the transverse electromagnetic (TEM) multi-element transceiver coil consisting of microstrip resonators. In this paper, to further advance this design approach, a new microstrip resonator strategy in which the transmission line is segmented into alternating impedance sections referred to as stepped impedance resonators (SIRs) is investigated. Single element simulation results in free space and in a phantom at 7 tesla (298 MHz) demonstrate the rationale and feasibility of the SIR design strategy. Simulation and image results at 7 tesla in a phantom and human head illustrate the improvements in transmit magnetic field, as well as, RF efficiency (transmit magnetic field versus SAR) when two different SIR designs are incorporated in 8-element volume coil configurations and compared to a volume coil consisting of microstrip elements. PMID:23508243

  14. 3D Electromagnetic Particle-in-Cell simulations of the solar wind interaction with lunar magnetic anomalies

    NASA Astrophysics Data System (ADS)

    Deca, J.; Lapenta, G.; Divin, A. V.; Lembege, B.; Markidis, S.

    2013-12-01

    Unlike the Earth and Mercury, our Moon has no global magnetic field and is therefore not shielded from the impinging solar wind by a magnetosphere. However, lunar magnetic field measurements made by the Apollo missions provided direct evidence that the Moon has regions of small-scale crustal magnetic fields, ranging up to a few 100km in scale size with surface magnetic field strengths up to hundreds of nanoTeslas. More recently, the Lunar Prospector spacecraft has provided high-resolution observations allowing to construct magnetic field maps of the entire Moon, confirming the earlier results from Apollo, but also showing that the lunar plasma environment is much richer than earlier believed. Typically the small-scale magnetic fields are non-dipolar and rather tiny compared to the lunar radius and mainly clustered on the far side of the moon. Using iPic3D we present the first 3D fully kinetic and electromagnetic Particle-in-Cell simulations of the solar wind interaction with lunar magnetic anomalies. We study the behaviour of a dipole model with variable surface magnetic field strength under changing solar wind conditions and confirm that lunar crustal magnetic fields may indeed be strong enough to stand off the solar wind and form a mini-magnetosphere, as suggested by MHD and hybrid simulations and spacecraft observations. 3D-PIC simulations reveal to be very helpful to analyze the diversion/braking of the particle flux and the characteristics of the resulting particles accumulation. The particle flux to the surface is significantly reduced at the magnetic anomaly, surrounded by a region of enhanced density due to the magnetic mirror effect. Second, the ability of iPic3D to resolve all plasma components (heavy ions, protons and electrons) allows to discuss in detail the electron physics leading to the highly non-adiabatic interactions expected as well as the implications for solar wind shielding of the lunar surface, depending on the scale size (solar wind protons

  15. Structure and magnetism of a binuclear Cu(II) pyrophosphate: transition to a 3D magnetic behaviour studied by single crystal EPR.

    PubMed

    Sartoris, Rosana P; Nascimento, Otaciro R; Santana, Ricardo C; Perec, Mireille; Baggio, Ricardo F; Calvo, Rafael

    2015-03-14

    A binuclear Cu(II) compound [Cu2(bpa)2(P2O7)(H2O)2]·2.5H2O, 1, (bpa = 2,2'-bipyridylamine), with pairs of Cu(II) ions bridged by one pyrophosphate tetra-anion, was synthesized and crystallized. Its triclinic structure was determined by single-crystal X-ray diffraction. Electron paramagnetic resonance (EPR) spectra of single crystal samples of 1 were recorded for a fixed orientation of the magnetic field (B0) as a function of temperature (T) between 4.7 and 293 K, and at T = 4.7, 50 and 293 K, as a function of the orientation of B0. Below ∼8 K, the spectra are assigned to two types of mononuclear crystal defects hyperfine-coupled to one copper and two nitrogen nuclei. The g-matrices and hyperfine couplings at these T provide information about the structures of these defects. Above 10 K, the spectrum is dominated by the response of the bulk binuclear Cu(II) material, showing hyperfine interactions with two copper nuclei, collapsing to a single peak above 18 K when the units are magnetically connected, and the magnetic behaviour becomes 3D. We attribute the results above 10 K to the interplay of an AFM intrabinuclear exchange interaction J0 = -28(3) cm(-1) (defined as Hex = -J0S1·S2), and three orders of magnitude weaker exchange coupling with average magnitude |J1| ≥ 0.022 cm(-1) between Cu(II) ions in neighbouring binuclear units. The interplays between structure, exchange couplings, magnetic dimension and spin dynamics in the binuclear compound are discussed. A previously unreported situation, where the structure of the spectra arising from the anisotropic spin-spin interaction term (D) within the binuclear unit is averaged out, but the forbidden half field transition is not, is observed and explained.

  16. 3D non-linear inversion of magnetic anomalies caused by prismatic bodies using differential evolution algorithm

    NASA Astrophysics Data System (ADS)

    Balkaya, Çağlayan; Ekinci, Yunus Levent; Göktürkler, Gökhan; Turan, Seçil

    2017-01-01

    3D non-linear inversion of total field magnetic anomalies caused by vertical-sided prismatic bodies has been achieved by differential evolution (DE), which is one of the population-based evolutionary algorithms. We have demonstrated the efficiency of the algorithm on both synthetic and field magnetic anomalies by estimating horizontal distances from the origin in both north and east directions, depths to the top and bottom of the bodies, inclination and declination angles of the magnetization, and intensity of magnetization of the causative bodies. In the synthetic anomaly case, we have considered both noise-free and noisy data sets due to two vertical-sided prismatic bodies in a non-magnetic medium. For the field case, airborne magnetic anomalies originated from intrusive granitoids at the eastern part of the Biga Peninsula (NW Turkey) which is composed of various kinds of sedimentary, metamorphic and igneous rocks, have been inverted and interpreted. Since the granitoids are the outcropped rocks in the field, the estimations for the top depths of two prisms representing the magnetic bodies were excluded during inversion studies. Estimated bottom depths are in good agreement with the ones obtained by a different approach based on 3D modelling of pseudogravity anomalies. Accuracy of the estimated parameters from both cases has been also investigated via probability density functions. Based on the tests in the present study, it can be concluded that DE is a useful tool for the parameter estimation of source bodies using magnetic anomalies.

  17. Magnetic resonance elastometry using a single-sided permanent magnet

    NASA Astrophysics Data System (ADS)

    Tan, Carl S.; Marble, Andrew E.; Ono, Yuu

    2012-04-01

    In this paper, we describe a magnetic resonance method of measuring material elasticity using a single-sided magnet with a permanent static field gradient. This method encodes sample velocity in a reciprocal space using Hahn spin-echoes with variable timing. The experimental results show a strong correlation between magnetic resonance signal attenuation and elasticity when an oscillating force is applied on the sample. This relationship in turn provides us with information about the displacement velocity experienced by the sample, which is inversely proportional to Young's modulus. The proposed method shows promise in offering a portable and cost-effective magnetic resonance elastography system.

  18. Magnetic resonance image guided brachytherapy.

    PubMed

    Tanderup, Kari; Viswanathan, Akila N; Kirisits, Christian; Frank, Steven J

    2014-07-01

    The application of magnetic resonance image (MRI)-guided brachytherapy has demonstrated significant growth during the past 2 decades. Clinical improvements in cervix cancer outcomes have been linked to the application of repeated MRI for identification of residual tumor volumes during radiotherapy. This has changed clinical practice in the direction of individualized dose administration, and resulted in mounting evidence of improved clinical outcome regarding local control, overall survival as well as morbidity. MRI-guided prostate high-dose-rate and low-dose-rate brachytherapies have improved the accuracy of target and organs-at-risk delineation, and the potential exists for improved dose prescription and reporting for the prostate gland and organs at risk. Furthermore, MRI-guided prostate brachytherapy has significant potential to identify prostate subvolumes and dominant lesions to allow for dose administration reflecting the differential risk of recurrence. MRI-guided brachytherapy involves advanced imaging, target concepts, and dose planning. The key issue for safe dissemination and implementation of high-quality MRI-guided brachytherapy is establishment of qualified multidisciplinary teams and strategies for training and education.

  19. [Presurgical functional magnetic resonance imaging].

    PubMed

    Stippich, C

    2010-02-01

    Functional magnetic resonance imaging (fMRI) is an important and novel neuroimaging modality for patients with brain tumors. By non-invasive measurement, localization and lateralization of brain activiation, most importantly of motor and speech function, fMRI facilitates the selection of the most appropriate and sparing treatment and function-preserving surgery. Prerequisites for the diagnostic use of fMRI are the application of dedicated clinical imaging protocols and standardization of the respective imaging procedures. The combination with diffusion tensor imaging (DTI) also enables tracking and visualization of important fiber bundles such as the pyramidal tract and the arcuate fascicle. These multimodal MR data can be implemented in computer systems for functional neuronavigation or radiation treatment. The practicability, accuracy and reliability of presurgical fMRI have been validated by large numbers of published data. However, fMRI cannot be considered as a fully established modality of diagnostic neuroimaging due to the lack of guidelines of the responsible medical associations as well as the lack of medical certification of important hardware and software components. This article reviews the current research in the field and provides practical information relevant for presurgical fMRI.

  20. A supervisor for the successive 3D computations of magnetic, mechanical and acoustic quantities in power oil inductors and transformers

    SciTech Connect

    Reyne, G.; Magnin, H.; Berliat, G.; Clerc, C.

    1994-09-01

    A supervisor has been developed so as to allow successive 3D computations of different quantities by different softwares on the same physical problem. Noise of a given power oil transformer can be deduced from the surface vibrations of the tank. These vibrations are obtained through a mechanic computation whose Inputs are the electromagnetic forces provided . by an electromagnetic computation. Magnetic, mechanic and acoustic experimental data are compared with the results of the 3D computations. Stress Is put on the main characteristics of the supervisor such as the transfer of a given quantity from one mesh to the other.

  1. Quantify Plasma Response to Non-Axisymmetric (3D) Magnetic Fields in Tokamaks, Final Report for FES (Fusion Energy Sciences) FY2014 Joint Research Target

    SciTech Connect

    Strait, E. J.; Park, J. -K.; Marmar, E. S.; Ahn, J. -W.; Berkery, J. W.; Burrell, K. H.; Canik, J. M.; Delgado-Aparicio, L.; Ferraro, N. M.; Garofalo, A. M.; Gates, D. A.; Greenwald, M.; Kim, K.; King, J. D.; Lanctot, M. J.; Lazerson, S. A.; Liu, Y. Q.; Lore, J. D.; Menard, J. E.; Nazikian, R.; Shafer, M. W.; Paz-Soldan, C.; Reiman, A. H.; Rice, J. E.; Sabbagh, S. A.; Sugiyama, L.; Turnbull, A. D.; Volpe, F.; Wang, Z. R.; Wolfe, S. M.

    2014-09-30

    The goal of the 2014 Joint Research Target (JRT) has been to conduct experiments and analysis to investigate and quantify the response of tokamak plasmas to non-axisymmetric (3D) magnetic fields. Although tokamaks are conceptually axisymmetric devices, small asymmetries often result from inaccuracies in the manufacture and assembly of the magnet coils, or from nearby magnetized objects. In addition, non-axisymmetric fields may be deliberately applied for various purposes. Even at small amplitudes of order 10-4 of the main axisymmetric field, such “3D” fields can have profound impacts on the plasma performance. The effects are often detrimental (reduction of stabilizing plasma rotation, degradation of energy confinement, localized heat flux to the divertor, or excitation of instabilities) but may in some case be beneficial (maintenance of rotation, or suppression of instabilities). In general, the magnetic response of the plasma alters the 3D field, so that the magnetic field configuration within the plasma is not simply the sum of the external 3D field and the original axisymmetric field. Typically the plasma response consists of a mixture of local screening of the external field by currents induced at resonant surfaces in the plasma, and amplification of the external field by stable kink modes. Thus, validated magnetohydrodynamic (MHD) models of the plasma response to 3D fields are crucial to the interpretation of existing experiments and the prediction of plasma performance in future devices. The non-axisymmetric coil sets available at each facility allow well-controlled studies of the response to external 3D fields. The work performed in support of the 2014 Joint Research Target has included joint modeling and analysis of existing experimental data, and collaboration on new experiments designed to address the goals of the JRT. A major focus of the work was validation of numerical models through quantitative comparison to experimental data, in

  2. 3D Seismic and Magnetic characterization of the Borax Lake Hydrothermal System in the Alvord Desert, southeastern Oregon.

    NASA Astrophysics Data System (ADS)

    Hess, S.; Bradford, J.; Lyle, M.; Routh, P.; Liberty, L.; Donaldson, P.

    2004-05-01

    As part of an interdisciplinary project aiming to study the link between the physical characteristics of hydrothermal systems and biota that occupy those systems, we are conducting a detailed geophysical characterization of an active hydrothermal system. The Borax Lake Hydrothermal System (BLHS), consisting of Borax Lake and the surrounding hot springs. BLHS is located near the center of the Alvord Basin in southeastern Oregon. The Alvord Basin is a north-south trending graben in the Northern Great Basin bounded by the Steens Mountains to the west and the Trout Creek Mountains to the east. We conducted a 2D seismic survey to characterize the geologic structure of the basin, a high-resolution 3D seismic survey to characterize the geologic structure of the BLHS, and a high-resolution 3D magnetic survey to characterize any lineaments in the bedrock that might control fluid flow in the BLHS. Previous results from the 2D seismic survey show a mid-basin basement high aligned approximately with the hot springs. In this study we present the results from the high-resolution 3D seismic and magnetic survey of the BLHS. We acquired the 3D seismic data using an SKS rifle and 240 channel recording system. The seismic survey covers approximately 90,000 sq. m with a maximum inline offset aperture of 225 m, crossline aperture of 75 m, and 360 degree azimuthal coverage. The coincidental magnetic survey was collected using a Geometrics 858G cesium vapor magnetometer. We designed both surveys to span nearly 100 active hydrothermal springs, including an approximately 50 m stepover in the trend of the surface expression of the hot springs. After preliminary processing, the 3D seismic data show continuous reflections up to 300 ms (~ 480 m). The initial interpretation of features seen in the 3D data cube include: normal faults dipping to the east and west, near-surface disturbances that are consistent with the trend of the hot springs, and significant near surface velocity anomalies

  3. M3D-C1 simulations of the plasma response to n = 3 magnetic perturbations applied to the NSTX-U snowflake divertor

    NASA Astrophysics Data System (ADS)

    Canal, G. P.; Ferraro, N. M.; Evans, T. E.; Osborne, T. H.; Menard, J. E.; Ahn, J.-W.; Maingi, R.; Wingen, A.; Ciro, D.; Frerichs, H.; Schmitz, O.; Soukhanoviskii, V.; Waters, I.

    2016-10-01

    Single- and two-fluid resistive magnetohydrodynamic simulations, performed with the code M3D-C1, are used to investigate the effect of n = 3 magnetic perturbations on the SF divertor configuration. The calculations are based on simulated NSTX-U plasmas and the results show that additional and longer magnetic lobes are created in the null-point region of the SF configuration, compared to those in the conventional single-null. The intersection of these additional and longer lobes with the divertor plates are expected to cause more striations in the particle and heat flux target profiles. In addition, the results indicate that the size of the magnetic lobes, in both single-null and SF configurations, are more sensitive to resonant than to non-resonant magnetic perturbations. The results also suggest that lower values of current in non-axisymmetric control coils close enough to the primary x-point would be required to suppress edge localized modes in plasmas with the SF configuration. This work has been supported by the US Department of Energy, Office of Science, Office of Fusion Energy Science under DOE Award DE-SC0012706.

  4. Reducing Field Distortion in Magnetic Resonance Imaging

    NASA Technical Reports Server (NTRS)

    Eom, Byeong Ho; Penanen, Konstantin; Hahn, Inseob

    2010-01-01

    A concept for a magnetic resonance imaging (MRI) system that would utilize a relatively weak magnetic field provides for several design features that differ significantly from the corresponding features of conventional MRI systems. Notable among these features are a magnetic-field configuration that reduces (relative to the conventional configuration) distortion and blurring of the image, the use of a superconducting quantum interference device (SQUID) magnetometer as the detector, and an imaging procedure suited for the unconventional field configuration and sensor. In a typical application of MRI, a radio-frequency pulse is used to excite precession of the magnetic moments of protons in an applied magnetic field, and the decaying precession is detected for a short time following the pulse. The precession occurs at a resonance frequency proportional to the strengths of the magnetic field and the proton magnetic moment. The magnetic field is configured to vary with position in a known way; hence, by virtue of the aforesaid proportionality, the resonance frequency varies with position in a known way. In other words, position is encoded as resonance frequency. MRI using magnetic fields weaker than those of conventional MRI offers several advantages, including cheaper and smaller equipment, greater compatibility with metallic objects, and higher image quality because of low susceptibility distortion and enhanced spin-lattice-relaxation- time contrast. SQUID MRI is being developed into a practical MRI method for applied magnetic flux densities of the order of only 100 T

  5. Miniature Magnet for Electron Spin Resonance Experiments

    ERIC Educational Resources Information Center

    Rupp, L. W.; And Others

    1976-01-01

    Describes commercially available permanent magnets that have been incorporated in a compact and inexpensive structure providing both field sweep and modulation suitable for electron spin resonance at microwave frequencies. (MLH)

  6. Magnetic resonance imaging of the cryptorchid testis.

    PubMed

    Landa, H M; Gylys-Morin, V; Mattrey, R F; Krous, H F; Kaplan, G W; Packer, M G

    1987-01-01

    Magnetic resonance imaging was used to evaluate seven patients with undescended testes. In six patients the presence or absence of testicular tissue was predicted correctly prior to surgery. Spermatic cord structures, if present, were accurately visualized in all patients.

  7. Coronary Computed Tomography and Magnetic Resonance Imaging

    PubMed Central

    Kantor, Birgit; Nagel, Eike; Schoenhagen, Paul; Barkhausen, Jörg; Gerber, Thomas C.

    2009-01-01

    Cardiac computed tomography and magnetic resonance are relatively new imaging modalities that can exceed the ability of established imaging modalities to detect present pathology or predict patient outcomes. Coronary calcium scoring may be useful in asymptomatic patients at intermediate risk. Computed tomographic coronary angiography is a first-line indication to evaluate congenitally abnormal coronary arteries and, along with stress magnetic resonance myocardial perfusion imaging, is useful in symptomatic patients with nondiagnostic conventional stress tests. Cardiac magnetic resonance is indicated for visualizing cardiac structure and function, and delayed enhancement magnetic resonance is a first-line indication for assessing myocardial viability. Imaging plaque and molecular mechanisms related to plaque rupture holds great promise for the presymptomatic detection of patients at risk for coronary events but is not yet suitable for routine clinical use. PMID:19269527

  8. Coronary computed tomography and magnetic resonance imaging.

    PubMed

    Kantor, Birgit; Nagel, Eike; Schoenhagen, Paul; Barkhausen, Jörg; Gerber, Thomas C

    2009-04-01

    Cardiac computed tomography and magnetic resonance are relatively new imaging modalities that can exceed the ability of established imaging modalities to detect present pathology or predict patient outcomes. Coronary calcium scoring may be useful in asymptomatic patients at intermediate risk. Computed tomographic coronary angiography is a first-line indication to evaluate congenitally abnormal coronary arteries and, along with stress magnetic resonance myocardial perfusion imaging, is useful in symptomatic patients with nondiagnostic conventional stress tests. Cardiac magnetic resonance is indicated for visualizing cardiac structure and function, and delayed enhancement magnetic resonance is a first-line indication for assessing myocardial viability. Imaging plaque and molecular mechanisms related to plaque rupture holds great promise for the presymptomatic detection of patients at risk for coronary events but is not yet suitable for routine clinical use.

  9. Pocket atlas of cranial magnetic resonance imaging

    SciTech Connect

    Haughton, V.M.; Daniels, D.L.

    1986-01-01

    This atlas illustrates normal cerebral anatomy in magnetic resonance images. From their studies in cerebral anatomy utilizing cryomicrotome and other techniques, the authors selected more than 100 high-resolution images that represent the most clinically useful scans.

  10. International Society for Magnetic Resonance in Medicine

    MedlinePlus

    ... Join the ISMRM Journals History & Mission Central Office Society Award Winners Strategic Plan Policies Corporate Members Contact ... E-Library Virtual Meetings Connect With Us International Society for Magnetic Resonance in Medicine 2300 Clayton Road, ...

  11. Chronic liver disease: evaluation by magnetic resonance

    SciTech Connect

    Stark, D.D.; Goldberg, H.I.; Moss, A.A.; Bass, N.M.

    1984-01-01

    Magnetic resonance (MR) imaging distinguished hepatitis from fatty liver and cirrhosis in a woman with a history of alcohol abuse. Anatomic and physiologic manifestations of portal hypertension were also demonstrated by MR.

  12. Polywater: proton nuclear magnetic resonance spectrum.

    PubMed

    Page, T F; Jakobsen, R J; Lippincott, E R

    1970-01-02

    In the presence of water, the resonance of the strongly hydrogenbonded protons characteristic of polywater appears at 5 parts per million lower applied magnetic field than water. Polywater made by a new method confirms the infrared spectrum reported originally.

  13. Inductively Driven, 3D Liner Compression of a Magnetized Plasma to Megabar Energy Densities

    SciTech Connect

    Slough, John

    2015-02-01

    modules. The additional energy and switching capability proposed will thus provide for optimal utilization of the liner energy. The following tasks were outlined for the three year effort: (1) Design and assemble the foil liner compression test structure and chamber including the compression bank and test foils [Year 1]. (2) Perform foil liner compression experiments and obtain performance data over a range on liner dimensions and bank parameters [Year 2]. (3) Carry out compression experiments of the FRC plasma to Megagauss fields and measure key fusion parameters [Year 3]. (4) Develop numerical codes and analyze experimental results, and determine the physics and scaling for future work [Year 1-3]. The principle task of the project was to design and assemble the foil liner FRC formation chamber, the full compression test structure and chamber including the compression bank. This task was completed successfully. The second task was to test foils in the test facility constructed in year one and characterize the performance obtained from liner compression. These experimental measurements were then compared with analytical predictions, and numerical code results. The liner testing was completed and compared with both the analytical results as well as the code work performed with the 3D structural dynamics package of ANSYS Metaphysics®. This code is capable of modeling the dynamic behavior of materials well into the non-linear regime (e.g. a bullet hit plate glass). The liner dynamic behavior was found to be remarkably close to that predicted by the 3D structural dynamics results. Incorporating a code that can also include the magnetics and plasma physics has also made significant progress at the UW. The remaining test bed construction and assembly task is was completed, and the FRC formation and merging experiments were carried out as planned. The liner compression of the FRC to Megagauss fields was not performed due to not obtaining a sufficiently long lived FRC during the

  14. Microfluidic Fabrication of Bio-Inspired Microfibers with Controllable Magnetic Spindle-Knots for 3D Assembly and Water Collection.

    PubMed

    He, Xiao-Heng; Wang, Wei; Liu, Ying-Mei; Jiang, Ming-Yue; Wu, Fang; Deng, Ke; Liu, Zhuang; Ju, Xiao-Jie; Xie, Rui; Chu, Liang-Yin

    2015-08-12

    A simple and flexible approach is developed for controllable fabrication of spider-silk-like microfibers with tunable magnetic spindle-knots from biocompatible calcium alginate for controlled 3D assembly and water collection. Liquid jet templates with volatile oil drops containing magnetic Fe3O4 nanoparticles are generated from microfluidics for fabricating spider-silk-like microfibers. The structure of jet templates can be precisely adjusted by simply changing the flow rates to tailor the structures of the resultant spider-silk-like microfibers. The microfibers can be well manipulated by external magnetic fields for controllably moving, and patterning and assembling into different 2D and 3D structures. Moreover, the dehydrated spider-silk-like microfibers, with magnetic spindle-knots for collecting water drops, can be controllably assembled into spider-web-like structures for excellent water collection. These spider-silk-like microfibers are promising as functional building blocks for engineering complex 3D scaffolds for water collection, cell culture, and tissue engineering.

  15. Single Nuclear Spin Magnetic Resonance Force Microscopy

    DTIC Science & Technology

    2010-05-02

    Lab. In work not directly supported by this grant, these projects advanced MRFM detected Ferromagnetic Resonance ( FMR ) to enable studies of...directly supported by this grant, these projects advanced MRFM detected Ferromagnetic Resonance ( FMR ) to enable studies of submicron magnetic structures...our earlier NMR detection of 19F spins in CaF2 we have conducted 65Cu, 63Cu NMR stud- ies for studies of interface phenomena in multilayered magnetic

  16. A Compressive Sensing Approach for 3D Breast Cancer Microwave Imaging With Magnetic Nanoparticles as Contrast Agent.

    PubMed

    Bevacqua, Martina T; Scapaticci, Rosa

    2016-02-01

    In microwave breast cancer imaging magnetic nanoparticles have been recently proposed as contrast agent. Due to the non-magnetic nature of human tissues, magnetic nanoparticles make possible the overcoming of some limitations of conventional microwave imaging techniques, thus providing reliable and specific diagnosis of breast cancer. In this paper, a Compressive Sensing inspired inversion technique is introduced for the reconstruction of the magnetic contrast induced within the tumor. The applicability of Compressive Sensing theory is guaranteed by the fact that the underlying inverse scattering problem is linear and the searched magnetic perturbation is sparse. From the numerical analysis, performed in realistic conditions in 3D geometry, it has been pointed out that the adoption of this new tool allows improving resolution and accuracy of the reconstructions, as well as reducing the number of required measurements.

  17. Defect energetics and magnetic properties of 3 d-transition-metal-doped topological crystalline insulator SnTe

    NASA Astrophysics Data System (ADS)

    Wang, Na; Wang, JianFeng; Si, Chen; Gu, Bing-Lin; Duan, WenHui

    2016-08-01

    The introduction of magnetism in SnTe-class topological crystalline insulators is a challenging subject with great importance in the quantum device applications. Based on the first-principles calculations, we have studied the defect energetics and magnetic properties of 3 d transition-metal (TM)-doped SnTe. We find that the doped TM atoms prefer to stay in the neutral states and have comparatively high formation energies, suggesting that the uniform TMdoping in SnTe with a higher concentration will be difficult unless clustering. In the dilute doping regime, all the magnetic TMatoms are in the high-spin states, indicating that the spin splitting energy of 3 d TM is stronger than the crystal splitting energy of the SnTe ligand. Importantly, Mn-doped SnTe has relatively low defect formation energy, largest local magnetic moment, and no defect levels in the bulk gap, suggesting that Mn is a promising magnetic dopant to realize the magnetic order for the theoretically-proposed large-Chern-number quantum anomalous Hall effect (QAHE) in SnTe.

  18. 3-D MHD modeling and stability analysis of jet and spheromak plasmas launched into a magnetized plasma

    NASA Astrophysics Data System (ADS)

    Fisher, Dustin; Zhang, Yue; Wallace, Ben; Gilmore, Mark; Manchester, Ward; Arge, C. Nick

    2016-10-01

    The Plasma Bubble Expansion Experiment (PBEX) at the University of New Mexico uses a coaxial plasma gun to launch jet and spheromak magnetic plasma configurations into the Helicon-Cathode (HelCat) plasma device. Plasma structures launched from the gun drag frozen-in magnetic flux into the background magnetic field of the chamber providing a rich set of dynamics to study magnetic turbulence, force-free magnetic spheromaks, and shocks. Preliminary modeling is presented using the highly-developed 3-D, MHD, BATS-R-US code developed at the University of Michigan. BATS-R-US employs an adaptive mesh refinement grid that enables the capture and resolution of shock structures and current sheets, and is particularly suited to model the parameter regime under investigation. CCD images and magnetic field data from the experiment suggest the stabilization of an m =1 kink mode trailing a plasma jet launched into a background magnetic field. Results from a linear stability code investigating the effect of shear-flow as a cause of this stabilization from magnetic tension forces on the jet will be presented. Initial analyses of a possible magnetic Rayleigh Taylor instability seen at the interface between launched spheromaks and their entraining background magnetic field will also be presented. Work supported by the Army Research Office Award No. W911NF1510480.

  19. Effect of magnetism on the solubility of 3 d elements in BCC iron: Results of first-principle investigations

    NASA Astrophysics Data System (ADS)

    Gorbatov, O. I.; Okatov, S. V.; Gornostyrev, Yu. N.; Korzhavyi, P. A.; Ruban, A. V.

    2013-08-01

    The methods of quantum-mechanical simulation have been used to study alloys of bcc iron with 3 d transition metals in the ferromagnetic and paramagnetic states. It has been shown that the main factor that determines the solubility of the 3 d elements is their electronic structure. The energy of the solution, mixing, and effective interatomic interactions vary regularly depending on the position of the element in the Periodic Table and on the magnetic state of the matrix. In some cases, depending on the magnetic state, changes in these quantities lead to the violation of the Hume-Rothery rules that determine the solubility of substitutional elements in alloys. The results obtained help us to understand the microscopic mechanisms that determine the solubility of alloying elements and their effect on the phase stability and structural state of steels.

  20. First MMS Observations of High Time Resolution 3D Electric and Magnetic fields at the Dayside Magnetopause.

    NASA Astrophysics Data System (ADS)

    Torbert, R. B.; Burch, J. L.; Russell, C. T.; Magnes, W.; Ergun, R. E.; Lindqvist, P. A.; Le Contel, O.; Vaith, H.; Macri, J.; Myers, S.; Rau, D.; Needell, J.; King, B.; Granoff, M.; Chutter, M.; Dors, I.; Argall, M. R.; Shuster, J. R.; Olsson, G.; Marklund, G. T.; Khotyaintsev, Y. V.; Eriksson, A. I.; Kletzing, C.; Bounds, S. R.; Anderson, B. J.; Baumjohann, W.; Steller, M.; Bromund, K. R.; Le, G.; Nakamura, R.; Strangeway, R. J.; Leinweber, H. K.; Tucker, S.; Westfall, J.; Fischer, D.; Plaschke, F.; Pollock, C. J.; Giles, B. L.; Moore, T. E.; Mauk, B.; Fuselier, S. A.

    2015-12-01

    The electrodynamics at the magnetopause is key to our understanding of ion and electron acceleration within reconnection regions. The Magnetospheric Multiscale (MMS) fleet of four spacecraft was launched into its Phase-1 equatorial orbit of 12 Re apogee specifically to investigate these regions at the Earth's magnetopause. In addition to a comprehensive suite of particle measurements, MMS makes very high time resolution 3D electric and magnetic field measurements of high accuracy using flux-gate, search coil, 3-axis double probe, and electron drift sensors. In September 2015, the MMS fleet will begin to encounter the dusk-side magnetopause in its initial configuration of approximately 160 km separation, allowing investigation of the spatial and temporal characteristics of important electrodynamics during reconnection. Using these field and particle measurements, we present first observations of 3D magnetic and electric fields (including their parallel component), and inferred current sheets, during active magnetopause crossings using the highest time resolution data available on MMS.

  1. Magnetic resonance force detection using a membrane resonator

    NASA Astrophysics Data System (ADS)

    Scozzaro, N.; Ruchotzke, W.; Belding, A.; Cardellino, J.; Blomberg, E. C.; McCullian, B. A.; Bhallamudi, V. P.; Pelekhov, D. V.; Hammel, P. C.

    2016-10-01

    The availability of compact, low-cost magnetic resonance imaging instruments would further broaden the substantial impact of this technology. We report highly sensitive detection of magnetic resonance using low-stress silicon nitride (SiNx) membranes. We use these membranes as low-loss, high-frequency mechanical oscillators and find they are able to mechanically detect spin-dependent forces with high sensitivity enabling ultrasensitive magnetic resonance detection. The high force detection sensitivity stems from their high mechanical quality factor Q ∼106 [1,2] combined with the low mass of the resonator. We use this excellent mechanical force sensitivity to detect the electron spin magnetic resonance using a SiNx membrane as a force detector. The demonstrated force sensitivity at 300 K is 4 fN/√{Hz } , indicating a potential low temperature (4 K) sensitivity of 25 aN/√{Hz } . Given their sensitivity, robust construction, large surface area and low cost, SiNx membranes can potentially serve as the central component of a compact room-temperature ESR and NMR instrument having spatial resolution superior to conventional approaches.

  2. Magnetic properties of Pd atomic chains formed during submonolayer deposition of 3d metals on Pd(110)

    NASA Astrophysics Data System (ADS)

    Stepanyuk, O. V.; Ignatiev, P. A.; Negulyaev, N. N.; Saletsky, A. M.; Hergert, W.

    2012-06-01

    Recently, an unusual intermixing-driven scenario for the growth of atomic Pd chains on a Pd(110) surface during deposition of 3d metal atoms has been predicted (Stepanyuk 2009 Phys. Rev. B 79 155410) and confirmed by STM and STS experiments (Wie et al 2009 Phys. Rev. Lett. 103 225504). Performing ab initio calculations we demonstrate that Pd atomic chains grown above embedded Fe atoms exhibit magnetic properties which depend on the substrate mediated exchange interaction between the Fe atoms.

  3. Magnetic properties of Pd atomic chains formed during submonolayer deposition of 3d metals on Pd(110).

    PubMed

    Stepanyuk, O V; Ignatiev, P A; Negulyaev, N N; Saletsky, A M; Hergert, W

    2012-06-13

    Recently, an unusual intermixing-driven scenario for the growth of atomic Pd chains on a Pd(110) surface during deposition of 3d metal atoms has been predicted (Stepanyuk 2009 Phys. Rev. B 79 155410) and confirmed by STM and STS experiments (Wie et al 2009 Phys. Rev. Lett. 103 225504). Performing ab initio calculations we demonstrate that Pd atomic chains grown above embedded Fe atoms exhibit magnetic properties which depend on the substrate mediated exchange interaction between the Fe atoms.

  4. Magnetic Resonance Imaging (MRI) Safety

    MedlinePlus

    ... radiation. Instead, MRI uses a powerful magnetic field, radio waves, rapidly changing magnetic fields, and a computer to ... in most of the body's tissues. The applied radio waves then cause these protons to produce signals that ...

  5. Investigation of Plutonic Rocks in Biga Peninsula, NW Turkey, using 3D Normalized Full Gradient of Magnetic Data

    NASA Astrophysics Data System (ADS)

    Ekinci, Y. L.; Yiǧitbaş, E.

    2012-04-01

    Airborne magnetic data of Biga Peninsula were investigated by using 3D Normalized Full Gradient (NFG) technique. The NFG procedure is based on the downward continuation of the potential field data and the NFG amplitude is calculated by dividing the Analytic Signal (AS) of downward continued magnetic data by the average of AS. Application of NFG technique usually enhances the anomalies by computing the anomaly to a level close to the source bodies and points to the boundaries of causative bodies. To that end, a MATLAB based code consisting of a series of linked functions was developed and used for analyses. Study area covers an area of 120 km x 180 km and the data were collected with 1-2 km profile intervals and with about 70 m sampling from 625 m above the ground surface by MTA (General Directorate of Mineral Research and Exploration). 2 km sampling intervals for both north and east directions were used for gridding of the magnetic data. Regional anomalies were approximated by means of element shape functions used in finite element method and then residuals were computed. Prior to the application of 3D NFG, Reduction to the Pole (RTP) transformation was applied to residual data in order to remove the complexity due to the effects of the direction of magnetization and ambient field. RTP transformation process was performed using 55 and 4 degrees for inclination and declination angles, respectively. 3D NFG operation was performed to reduced to pole data for 6 different depth levels (-200, -400, -600, -800, -1000 and -1200 m). Analyzing the resulting anomaly maps of different depth levels together with the geological map (1/500.000) showed that the locations of maximum NFG amplitudes indicate the boundaries of plutonic rocks having high magnetization intensity. Additionally, horizontal and vertical extensions of plutonic rocks were also determined. Keywords: Airborne magnetic data, normalized full gradient, plutonic rocks, Biga Peninsula-Turkey

  6. Dual-domain denoising in three dimensional magnetic resonance imaging.

    PubMed

    Peng, Jing; Zhou, Jiliu; Wu, Xi

    2016-08-01

    Denoising is a crucial preprocessing procedure for three dimensional magnetic resonance imaging (3D MRI). Existing denoising methods are predominantly implemented in a single domain, ignoring information in other domains. However, denoising methods are becoming increasingly complex, making analysis and implementation challenging. The present study aimed to develop a dual-domain image denoising (DDID) algorithm for 3D MRI that encapsulates information from the spatial and transform domains. In the present study, the DDID method was used to distinguish signal from noise in the spatial and frequency domains, after which robust accurate noise estimation was introduced for iterative filtering, which is simple and beneficial for computation. In addition, the proposed method was compared quantitatively and qualitatively with existing methods for synthetic and in vivo MRI datasets. The results of the present study suggested that the novel DDID algorithm performed well and provided competitive results, as compared with existing MRI denoising filters.

  7. Simulation of the 3-D Evolution of Electron Scale Magnetic Reconnection - Motivated by Laboratory Experiments Predictions for MMS

    NASA Astrophysics Data System (ADS)

    Buechner, J.; Jain, N.; Sharma, A.

    2013-12-01

    The four s/c of the Magnetospheric Multiscale (MMS) mission, to be launched in 2014, will use the Earth's magnetosphere as a laboratory to study the microphysics of three fundamental plasma processes. One of them is magnetic reconnection, an essentially multi-scale process. While laboratory experiments and past theoretical investigations have shown that important processes necessary to understand magnetic reconnection take place at electron scales the MMS mission for the first time will be able to resolve these scales by in space observations. For the measurement strategy of MMS it is important to make specific predictions of the behavior of current sheets with a thickness of the order of the electron skin depth which play an important role in the evolution of collisionless magnetic reconnection. Since these processes are highly nonlinear and non-local numerical simulation is needed to specify the current sheet evolution. Here we present new results about the nonlinear evolution of electron-scale current sheets starting from the linear stage and using 3-D electron-magnetohydrodynamic (EMHD) simulations. The growth rates of the simulated instabilities compared well with the growth rates obtained from linear theory. Mechanisms and conditions of the formation of flux ropes and of current filamentation will be discussed in comparison with the results of fully kinetic simulations. In 3D the X- and O-point configurations of the magnetic field formed in reconnection planes alternate along the out-of-reconnection-plane direction with the wavelength of the unstable mode. In the presence of multiple reconnection sites, the out-of-plane magnetic field can develop nested structure of quadrupoles in reconnection planes, similar to the 2-D case, but now with variations in the out-of-plane direction. The structures of the electron flow and magnetic field in 3-D simulations will be compared with those in 2-D simulations to discriminate the essentially 3D features. We also discuss

  8. New 3D parallel GILD electromagnetic modeling and nonlinear inversion using global magnetic integral and local differential equation

    SciTech Connect

    Xie, G.; Li, J.; Majer, E.; Zuo, D.

    1998-07-01

    This paper describes a new 3D parallel GILD electromagnetic (EM) modeling and nonlinear inversion algorithm. The algorithm consists of: (a) a new magnetic integral equation instead of the electric integral equation to solve the electromagnetic forward modeling and inverse problem; (b) a collocation finite element method for solving the magnetic integral and a Galerkin finite element method for the magnetic differential equations; (c) a nonlinear regularizing optimization method to make the inversion stable and of high resolution; and (d) a new parallel 3D modeling and inversion using a global integral and local differential domain decomposition technique (GILD). The new 3D nonlinear electromagnetic inversion has been tested with synthetic data and field data. The authors obtained very good imaging for the synthetic data and reasonable subsurface EM imaging for the field data. The parallel algorithm has high parallel efficiency over 90% and can be a parallel solver for elliptic, parabolic, and hyperbolic modeling and inversion. The parallel GILD algorithm can be extended to develop a high resolution and large scale seismic and hydrology modeling and inversion in the massively parallel computer.

  9. Finite Element Treatment of Vortex States in 3D Cubic Superconductors in a Tilted Magnetic Field

    NASA Astrophysics Data System (ADS)

    Peng, Lin; Cai, Chuanbing

    2017-03-01

    The time-dependent Ginzburg-Landau equations have been solved numerically by a finite element analysis for superconducting samples with a cubic shape in a tilted magnetic field. We obtain different vortex patterns as a function of the external magnetic field. With a magnetic field not parallel to the x- or y-axis, the vortices attempt to change their orientation accordingly. Our analysis of the corresponding changes in the magnetic response in different directions can provide information not only about vorticity but also about the three-dimensional vortex arrangement, even about the very subtle changes for the superconducting samples with a cubic shape in a tilted magnetic field.

  10. Analyses of Magnetic Structures of Active Region 11117 Evolution using a 3D Data-Driven Magnetohydrodynamic Model

    NASA Astrophysics Data System (ADS)

    Wu, Shi; Jiang, Chaowei; Feng, Xueshang

    We use the photospheric vector magnetograms obtained by Helioseismic and Magnetic Image (HMI) on-board the Solar Dynamic Observatory (SDO) as the boundary conditions for a Data-Driven CESE-MHD model (Jiang et al. 2012) to investigate the physical characteristics and evolution of magnetic field configurations in the corona before and after a solar eruptive event. Specifically, the evolution of AR11117 characteristics such as length of magnetic shear along the neutral line, current helicity, magnetic free energy and the energy flux across the photosphere due to flux emergence and surface flow are presented. The computed 3D magnetic field configuration are compared with AIA (Atmosphere Image Assembly) which shows remarkable resemblance. A topological analyses reveals that the small flare is correlated with a bald patch (BP, where the magnetic field is tangent to the photosphere), suggesting that the energy release of the flare is caused by magnetic reconnection associated with the BP separatrices. The total magnetic flux and energy keep increasing slightly in spite of flare, while the computed magnetic free energy drops during the flare by 10 (30) ergs which is adequate in providing the energy budget of a minor C-class confined flare as observed. Jiang, Chaowei, Xueshang, Feng, S. T Wu and Qiang Hu, Ap. J., 759:85, 2012 Nov 10

  11. Identification of cortex in magnetic resonance images

    NASA Astrophysics Data System (ADS)

    VanMeter, John W.; Sandon, Peter A.

    1992-06-01

    The overall goal of the work described here is to make available to the neurosurgeon in the operating room an on-line, three-dimensional, anatomically labeled model of the patient brain, based on pre-operative magnetic resonance (MR) images. A stereotactic operating microscope is currently in experimental use, which allows structures that have been manually identified in MR images to be made available on-line. We have been working to enhance this system by combining image processing techniques applied to the MR data with an anatomically labeled 3-D brain model developed from the Talairach and Tournoux atlas. Here we describe the process of identifying cerebral cortex in the patient MR images. MR images of brain tissue are reasonably well described by material mixture models, which identify each pixel as corresponding to one of a small number of materials, or as being a composite of two materials. Our classification algorithm consists of three steps. First, we apply hierarchical, adaptive grayscale adjustments to correct for nonlinearities in the MR sensor. The goal of this preprocessing step, based on the material mixture model, is to make the grayscale distribution of each tissue type constant across the entire image. Next, we perform an initial classification of all tissue types according to gray level. We have used a sum of Gaussian's approximation of the histogram to perform this classification. Finally, we identify pixels corresponding to cortex, by taking into account the spatial patterns characteristic of this tissue. For this purpose, we use a set of matched filters to identify image locations having the appropriate configuration of gray matter (cortex), cerebrospinal fluid and white matter, as determined by the previous classification step.

  12. Influence of Critical Current Density on Magnetic Force of Htsc Bulk above Pmr with 3D-MODELING Numerical Solutions

    NASA Astrophysics Data System (ADS)

    Lu, Yiyun; Lu, Bingjuan; Ge, Yunwang; Chen, Wenqing

    Numerical electromagnetic field simulations of high-temperature superconductors (HTSC) bulk were carried out to calculate the magnetic force between the HTSC bulk and the permanent magnet railway (PMR). A 3D-modeling numerical calculation method is proposed using the finite element method. The model is formulated with the magnetic field vector (H-method). The resulting code was written with FORTRAN language. The electric field intensity E and the current density J constitutive relation of HTSC were described with E-J power law. The Kim macro-model is used to describe critical current density Jc of HTSC bulk. Two virtual HTSC bulks were used to solve the critical current density Jc anisotropic properties of HTSC materials. A superconducting levitation system composed of one HTSC bulk and PMR is successfully investigated using the proposed method. By this method, the influence of critical current density on magnetic levitation force of the superconducting levitation system is mathematically studied.

  13. Investigation of laser polarized xenon magnetic resonance

    NASA Technical Reports Server (NTRS)

    Walsworth, Ronald L.

    1998-01-01

    Ground-based investigations of a new biomedical diagnostic technology: nuclear magnetic resonance of laser polarized noble gas are addressed. The specific research tasks discussed are: (1) Development of a large-scale noble gas polarization system; (2) biomedical investigations using laser polarized noble gas in conventional (high magnetic field) NMR systems; and (3) the development and application of a low magnetic field system for laser polarized noble gas NMR.

  14. Coherence of magnetic resonators in a metamaterial

    SciTech Connect

    Hou, Yumin

    2013-12-15

    The coherence of periodic magnetic resonators (MRs) under oblique incidence is studied using simulations. The correlated phase of interaction including both the retardation effect and relative phase difference between two MRs is defined, and it plays a key role in the MR interaction. The correlated phase is anisotropic, as is the coherence condition. The coherence condition is the same as the Wood's anomaly and verified by the Fano resonance. This study shows that the applications of the Fano resonance of periodic MRs will become widespread owing to achieving the Fano resonance simply by tuning the incident angle.

  15. Nuclear Magnetic Resonance Technology for Medical Studies

    NASA Astrophysics Data System (ADS)

    Budinger, Thomas F.; Lauterbur, Paul C.

    1984-10-01

    Nuclear magnetic resonance proton imaging provides anatomical definition of normal and abnormal tissues with a contrast and detection sensitivity superior to those of x-ray computed tomography in the human head and pelvis and parts of the cardiovascular and musculoskeletal systems. Recent improvements in technology should lead to advances in diagnostic imaging of the breast and regions of the abdomen. Selected-region nuclear magnetic resonance spectroscopy of protons, carbon-13, and phosphorus-31 has developed into a basic science tool for in vivo studies on man and a unique tool for clinical diagnoses of metabolic disorders. At present, nuclear magnetic resonance is considered safe if access to the magnet environment is controlled. Technological advances employing field strengths over 2 teslas will require biophysical studies of heating and static field effects.

  16. Enhancing the sensitivity of magnetic sensors by 3D metamaterial shells

    PubMed Central

    Navau, Carles; Mach-Batlle, Rosa; Parra, Albert; Prat-Camps, Jordi; Laut, Sergi; Del-Valle, Nuria; Sanchez, Alvaro

    2017-01-01

    Magnetic sensors are key elements in our interconnected smart society. Their sensitivity becomes essential for many applications in fields such as biomedicine, computer memories, geophysics, or space exploration. Here we present a universal way of increasing the sensitivity of magnetic sensors by surrounding them with a spherical metamaterial shell with specially designed anisotropic magnetic properties. We analytically demonstrate that the magnetic field in the sensing area is enhanced by our metamaterial shell by a known factor that depends on the shell radii ratio. When the applied field is non-uniform, as for dipolar magnetic field sources, field gradient is increased as well. A proof-of-concept experimental realization confirms the theoretical predictions. The metamaterial shell is also shown to concentrate time-dependent magnetic fields upto frequencies of 100 kHz. PMID:28303951

  17. Enhancing the sensitivity of magnetic sensors by 3D metamaterial shells.

    PubMed

    Navau, Carles; Mach-Batlle, Rosa; Parra, Albert; Prat-Camps, Jordi; Laut, Sergi; Del-Valle, Nuria; Sanchez, Alvaro

    2017-03-17

    Magnetic sensors are key elements in our interconnected smart society. Their sensitivity becomes essential for many applications in fields such as biomedicine, computer memories, geophysics, or space exploration. Here we present a universal way of increasing the sensitivity of magnetic sensors by surrounding them with a spherical metamaterial shell with specially designed anisotropic magnetic properties. We analytically demonstrate that the magnetic field in the sensing area is enhanced by our metamaterial shell by a known factor that depends on the shell radii ratio. When the applied field is non-uniform, as for dipolar magnetic field sources, field gradient is increased as well. A proof-of-concept experimental realization confirms the theoretical predictions. The metamaterial shell is also shown to concentrate time-dependent magnetic fields upto frequencies of 100 kHz.

  18. Enhancing the sensitivity of magnetic sensors by 3D metamaterial shells

    NASA Astrophysics Data System (ADS)

    Navau, Carles; Mach-Batlle, Rosa; Parra, Albert; Prat-Camps, Jordi; Laut, Sergi; Del-Valle, Nuria; Sanchez, Alvaro

    2017-03-01

    Magnetic sensors are key elements in our interconnected smart society. Their sensitivity becomes essential for many applications in fields such as biomedicine, computer memories, geophysics, or space exploration. Here we present a universal way of increasing the sensitivity of magnetic sensors by surrounding them with a spherical metamaterial shell with specially designed anisotropic magnetic properties. We analytically demonstrate that the magnetic field in the sensing area is enhanced by our metamaterial shell by a known factor that depends on the shell radii ratio. When the applied field is non-uniform, as for dipolar magnetic field sources, field gradient is increased as well. A proof-of-concept experimental realization confirms the theoretical predictions. The metamaterial shell is also shown to concentrate time-dependent magnetic fields upto frequencies of 100 kHz.

  19. Mini-conference Poster: 3D Onset and Propagation of Magnetic Reconnection

    NASA Astrophysics Data System (ADS)

    Lapenta, Giovanni; Ricci, P.; Brackbill, J. U.; Daughton, W.; Delzanno, G. L.

    2005-10-01

    A fundamental problem in reconnection physics is how to relate 2D and 3D reconnection. The great majority of studies of reconnection focus on 2D configurations. The state of affair is best described by the cave allegory of Plato. In 2D we look at the reconnection process as if we were studying the real world through its reflections on the walls of a cave [1]. We propose to turn our head away from the familiar wall and face the real world. We do 3D fully kinetic (i.e. both electrons and ions are kinetic) simulations of reconnection. We use the implicit PIC code CELESTE to achieve parameter ranges and system sizes inaccessible to traditional explicit codes. Our results will clarify the fundamental issue: if reconnection is started at one location, does it propagate in the system? How? And what coupling of microscopic and macroscopic processes causes the reconnection onset in the first place? All these effects can only be studied in 3D [2]. The crucial physics missing in 2D simulations is the role of macroscopic equilibrium changes induced by the microinstabilities [3].1) Plato, Republic, Book VII, Hackett Pub. Co., 1992. 2) P. Ricci, J.U. Brackbill, W.S. Daughton, G. Lapenta, Phys. Plasmas, 11, 4489, 2004.3) W. Daughton, G. Lapenta, P. Ricci, Phys. Rev. Lett., 93, 105004, 2004.

  20. Simple and Inexpensive Classroom Demonstrations of Nuclear Magnetic Resonance and Magnetic Resonance Imaging

    NASA Astrophysics Data System (ADS)

    Olson, Joel A.; Nordell, Karen J.; Chesnik, Marla A.; Landis, Clark R.; Ellis, Arthur B.; Rzchowski, M. S.; Condren, S. Michael; Lisensky, George C.

    2000-07-01

    Several demonstrations of resonance phenomena associated with nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are described. The demonstrations comprise common orienteering compasses, whose needles represent magnetic dipoles, along with three collinear permanent magnets and a magnetic stir plate or pulseable electromagnets. The trio of permanent magnets provides a laterally uniform magnetic field, whose strength decreases with distance from the magnets. Resonance can be observed by adjusting the frequency of the magnetic stirrer to match the resonant frequency of the compass needle, which is shown to depend on magnetic field strength, that is, the needle's position relative to the permanent magnets. Another demonstration involves pulsing electromagnets that apply a perpendicular magnetic field that causes the compass needles to oscillate. The effects of shielding, spin-spin coupling, magnetogyric ratio, and free induction decay can also be demonstrated. By moving the trio of permanent magnets relative to the compasses, the MRI experiment can be mimicked. Complete instructions for the construction of the demonstrations, which can be used on an overhead projector, are included.

  1. Discrete decoding based ultrafast multidimensional nuclear magnetic resonance spectroscopy

    SciTech Connect

    Wei, Zhiliang; Lin, Liangjie; Ye, Qimiao; Li, Jing; Cai, Shuhui; Chen, Zhong

    2015-07-14

    The three-dimensional (3D) nuclear magnetic resonance (NMR) spectroscopy constitutes an important and powerful tool in analyzing chemical and biological systems. However, the abundant 3D information arrives at the expense of long acquisition times lasting hours or even days. Therefore, there has been a continuous interest in developing techniques to accelerate recordings of 3D NMR spectra, among which the ultrafast spatiotemporal encoding technique supplies impressive acquisition speed by compressing a multidimensional spectrum in a single scan. However, it tends to suffer from tradeoffs among spectral widths in different dimensions, which deteriorates in cases of NMR spectroscopy with more dimensions. In this study, the discrete decoding is proposed to liberate the ultrafast technique from tradeoffs among spectral widths in different dimensions by focusing decoding on signal-bearing sites. For verifying its feasibility and effectiveness, we utilized the method to generate two different types of 3D spectra. The proposed method is also applicable to cases with more than three dimensions, which, based on the experimental results, may widen applications of the ultrafast technique.

  2. Magnetic nanoparticles in magnetic resonance imaging and diagnostics.

    PubMed

    Rümenapp, Christine; Gleich, Bernhard; Haase, Axel

    2012-05-01

    Magnetic nanoparticles are useful as contrast agents for magnetic resonance imaging (MRI). Paramagnetic contrast agents have been used for a long time, but more recently superparamagnetic iron oxide nanoparticles (SPIOs) have been discovered to influence MRI contrast as well. In contrast to paramagnetic contrast agents, SPIOs can be functionalized and size-tailored in order to adapt to various kinds of soft tissues. Although both types of contrast agents have a inducible magnetization, their mechanisms of influence on spin-spin and spin-lattice relaxation of protons are different. A special emphasis on the basic magnetism of nanoparticles and their structures as well as on the principle of nuclear magnetic resonance is made. Examples of different contrast-enhanced magnetic resonance images are given. The potential use of magnetic nanoparticles as diagnostic tracers is explored. Additionally, SPIOs can be used in diagnostic magnetic resonance, since the spin relaxation time of water protons differs, whether magnetic nanoparticles are bound to a target or not.

  3. Combined magnetic vector-scalar potential finite element computation of 3D magnetic field and performance of modified Lundell alternators in Space Station applications. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Wang, Ren H.

    1991-01-01

    A method of combined use of magnetic vector potential (MVP) based finite element (FE) formulations and magnetic scalar potential (MSP) based FE formulations for computation of three-dimensional (3D) magnetostatic fields is developed. This combined MVP-MSP 3D-FE method leads to considerable reduction by nearly a factor of 3 in the number of unknowns in comparison to the number of unknowns which must be computed in global MVP based FE solutions. This method allows one to incorporate portions of iron cores sandwiched in between coils (conductors) in current-carrying regions. Thus, it greatly simplifies the geometries of current carrying regions (in comparison with the exclusive MSP based methods) in electric machinery applications. A unique feature of this approach is that the global MSP solution is single valued in nature, that is, no branch cut is needed. This is again a superiority over the exclusive MSP based methods. A Newton-Raphson procedure with a concept of an adaptive relaxation factor was developed and successfully used in solving the 3D-FE problem with magnetic material anisotropy and nonlinearity. Accordingly, this combined MVP-MSP 3D-FE method is most suited for solution of large scale global type magnetic field computations in rotating electric machinery with very complex magnetic circuit geometries, as well as nonlinear and anisotropic material properties.

  4. Combined magnetic vector-scalar potential finite element computation of 3D magnetic field and performance of modified Lundell alternators in Space Station applications

    NASA Astrophysics Data System (ADS)

    Wang, Ren H.

    1991-02-01

    A method of combined use of magnetic vector potential (MVP) based finite element (FE) formulations and magnetic scalar potential (MSP) based FE formulations for computation of three-dimensional (3D) magnetostatic fields is developed. This combined MVP-MSP 3D-FE method leads to considerable reduction by nearly a factor of 3 in the number of unknowns in comparison to the number of unknowns which must be computed in global MVP based FE solutions. This method allows one to incorporate portions of iron cores sandwiched in between coils (conductors) in current-carrying regions. Thus, it greatly simplifies the geometries of current carrying regions (in comparison with the exclusive MSP based methods) in electric machinery applications. A unique feature of this approach is that the global MSP solution is single valued in nature, that is, no branch cut is needed. This is again a superiority over the exclusive MSP based methods. A Newton-Raphson procedure with a concept of an adaptive relaxation factor was developed and successfully used in solving the 3D-FE problem with magnetic material anisotropy and nonlinearity. Accordingly, this combined MVP-MSP 3D-FE method is most suited for solution of large scale global type magnetic field computations in rotating electric machinery with very complex magnetic circuit geometries, as well as nonlinear and anisotropic material properties.

  5. Structural, electronic and magnetic properties of 3d metal trioxide clusters-doped monolayer graphene: A first-principles study

    NASA Astrophysics Data System (ADS)

    Rafique, Muhammad; Shuai, Yong; Tan, He-Ping; Hassan, Muhammad

    2017-03-01

    We present first-principles density-functional calculations for the structural, electronic and magnetic properties of monolayer graphene doped with 3d (Ti, V, Cr, Fe, Co, Mn and Ni) metal trioxide TMO3 halogen clusters. In this paper we used two approaches for 3d metal trioxide clusters (i) TMO3 halogen cluster was embedded in monolayer graphene substituting four carbon (C) atoms (ii) three C atoms were substituted by three oxygen (O) atoms in one graphene ring and TM atom was adsorbed at the hollow site of O atoms substituted graphene ring. All the impurities were tightly bonded in the graphene ring. In first case of TMO3 doped graphene layer, the bond length between Csbnd O atom was reduced and bond length between TM-O atom was increased. In case of Cr, Fe, Co and Ni atoms substitution in between the O atoms, leads to Fermi level shifting to conduction band thereby causing the Dirac cone to move into valence band, however a band gap appears at high symmetric K-point. In case of TiO3 and VO3 substitution, system exhibits semiconductor properties. Interestingly, TiO3-substituted system shows dilute magnetic semiconductor behavior with 2.00 μB magnetic moment. On the other hand, the substitution of CoO3, CrO3, FeO3 and MnO3 induced 1.015 μB, 2.347 μB, 2.084 μB and 3.584 μB magnetic moment, respectively. In second case of O atoms doped in graphene and TM atoms adsorbed at the hollow site, the O atom bulges out of graphene plane and bond length between TM-O atom is increased. After TM atoms adsorption at the O substituted graphene ring the Fermi level (EF) shifts into conduction band. In case of Cr and Ni adsorption, system displays indirect band gap semiconductor properties with 0.0 μB magnetic moment. Co adsorption exhibits dilute magnetic semiconductor behavior producing 0.916 μB magnetic moment. Fe, Mn, Ti and V adsorption introduces band gap at high symmetric K-point also inducing 1.54 μB, 0.9909 μB, 1.912 μB, and 0.98 μB magnetic moments, respectively

  6. A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging

    PubMed Central

    Tseng, Hubert; Gage, Jacob A.; Shen, Tsaiwei; Haisler, William L.; Neeley, Shane K.; Shiao, Sue; Chen, Jianbo; Desai, Pujan K.; Liao, Angela; Hebel, Chris; Raphael, Robert M.; Becker, Jeanne L.; Souza, Glauco R.

    2015-01-01

    An ongoing challenge in biomedical research is the search for simple, yet robust assays using 3D cell cultures for toxicity screening. This study addresses that challenge with a novel spheroid assay, wherein spheroids, formed by magnetic 3D bioprinting, contract immediately as cells rearrange and compact the spheroid in relation to viability and cytoskeletal organization. Thus, spheroid size can be used as a simple metric for toxicity. The goal of this study was to validate spheroid contraction as a cytotoxic endpoint using 3T3 fibroblasts in response to 5 toxic compounds (all-trans retinoic acid, dexamethasone, doxorubicin, 5′-fluorouracil, forskolin), sodium dodecyl sulfate (+control), and penicillin-G (−control). Real-time imaging was performed with a mobile device to increase throughput and efficiency. All compounds but penicillin-G significantly slowed contraction in a dose-dependent manner (Z’ = 0.88). Cells in 3D were more resistant to toxicity than cells in 2D, whose toxicity was measured by the MTT assay. Fluorescent staining and gene expression profiling of spheroids confirmed these findings. The results of this study validate spheroid contraction within this assay as an easy, biologically relevant endpoint for high-throughput compound screening in representative 3D environments. PMID:26365200

  7. 3D magnetic field configuration of small-scale reconnection events in the solar plasma atmosphere

    NASA Astrophysics Data System (ADS)

    Shimizu, T.

    2015-10-01

    The outer solar atmosphere, i.e., the corona and the chromosphere, is replete with small energy-release events, which are accompanied by transient brightening and jet-like ejections. These events are considered to be magnetic reconnection events in the solar plasma, and their dynamics have been studied using recent advanced observations from the Hinode spacecraft and other observatories in space and on the ground. These events occur at different locations in the solar atmosphere and vary in their morphology and amount of the released energy. The magnetic field configurations of these reconnection events are inferred based on observations of magnetic fields at the photospheric level. Observations suggest that these magnetic configurations can be classified into two groups. In the first group, two anti-parallel magnetic fields reconnect to each other, yielding a 2D emerging flux configuration. In the second group, helical or twisted magnetic flux tubes are parallel or at a relative angle to each other. Reconnection can occur only between anti-parallel components of the magnetic flux tubes and may be referred to as component reconnection. The latter configuration type may be more important for the larger class of small-scale reconnection events. The two types of magnetic configurations can be compared to counter-helicity and co-helicity configurations, respectively, in laboratory plasma collision experiments.

  8. 3D magnetic field configuration of small-scale reconnection events in the solar plasma atmosphere

    SciTech Connect

    Shimizu, T.

    2015-10-15

    The outer solar atmosphere, i.e., the corona and the chromosphere, is replete with small energy-release events, which are accompanied by transient brightening and jet-like ejections. These events are considered to be magnetic reconnection events in the solar plasma, and their dynamics have been studied using recent advanced observations from the Hinode spacecraft and other observatories in space and on the ground. These events occur at different locations in the solar atmosphere and vary in their morphology and amount of the released energy. The magnetic field configurations of these reconnection events are inferred based on observations of magnetic fields at the photospheric level. Observations suggest that these magnetic configurations can be classified into two groups. In the first group, two anti-parallel magnetic fields reconnect to each other, yielding a 2D emerging flux configuration. In the second group, helical or twisted magnetic flux tubes are parallel or at a relative angle to each other. Reconnection can occur only between anti-parallel components of the magnetic flux tubes and may be referred to as component reconnection. The latter configuration type may be more important for the larger class of small-scale reconnection events. The two types of magnetic configurations can be compared to counter-helicity and co-helicity configurations, respectively, in laboratory plasma collision experiments.

  9. Crystal, magnetic and electronic structures of 3d-5d ordered double perovskite Ba2CoReO6

    NASA Astrophysics Data System (ADS)

    Musa Saad H.-E., M.; Rammeh, N.

    2016-12-01

    A comprehensive study on crystal, magnetic and electronic structures of ordered double perovskite Ba2CoReO6 was carried out using X-ray powder diffraction (XRD) and superconducting quantum interference device (SQUID). Also, the density functional theory (DFT) calculations were performed by full potential linear muffin-tin orbital (FP-LMTO) method within the localized spin density approximation (LSDA+U) and generalized gradient approximation (GGA+U). At room temperature, the crystal structure of Ba2CoReO6 is face-centered cubic, space group Fm 3 bar m , containing an almost completely ordered arrangement of CoO6-ReO6 octahedra. Magnetic structure showed an antiferromagnetic (AF) behavior below TN=41 K. The magnetic and electronic structures are consistent with the electronic configurations Co2+(3d7)-Re6+(5d1) having a total spin magnetic moment of about 2.0 μB/f.u. DFT electronic structures predicted half-metallic yields from 3d-t2g↓ and 5d-t2g↓ through O2-.

  10. Fast 3-D large-scale gravity and magnetic modeling using unstructured grids and an adaptive multilevel fast multipole method

    NASA Astrophysics Data System (ADS)

    Ren, Zhengyong; Tang, Jingtian; Kalscheuer, Thomas; Maurer, Hansruedi

    2017-01-01

    A novel fast and accurate algorithm is developed for large-scale 3-D gravity and magnetic modeling problems. An unstructured grid discretization is used to approximate sources with arbitrary mass and magnetization distributions. A novel adaptive multilevel fast multipole (AMFM) method is developed to reduce the modeling time. An observation octree is constructed on a set of arbitrarily distributed observation sites, while a source octree is constructed on a source tetrahedral grid. A novel characteristic is the independence between the observation octree and the source octree, which simplifies the implementation of different survey configurations such as airborne and ground surveys. Two synthetic models, a cubic model and a half-space model with mountain-valley topography, are tested. As compared to analytical solutions of gravity and magnetic signals, excellent agreements of the solutions verify the accuracy of our AMFM algorithm. Finally, our AMFM method is used to calculate the terrain effect on an airborne gravity data set for a realistic topography model represented by a triangular surface retrieved from a digital elevation model. Using 16 threads, more than 5800 billion interactions between 1,002,001 observation points and 5,839,830 tetrahedral elements are computed in 453.6 s. A traditional first-order Gaussian quadrature approach requires 3.77 days. Hence, our new AMFM algorithm not only can quickly compute the gravity and magnetic signals for complicated problems but also can substantially accelerate the solution of 3-D inversion problems.

  11. Pediatric obesity phenotyping by magnetic resonance methods

    PubMed Central

    Shen, Wei; Liu, Haiying; Punyanitya, Mark; Chen, Jun; Heymsfield, Steven B.

    2007-01-01

    Purpose of review Accurate measurement of adiposity in obese children is required for characterizing the condition’s phenotype, severity, and treatment effects in vivo. Non-invasive and safe, magnetic resonance imaging and spectroscopy provide an important new approach for characterizing key aspects of pediatric obesity. This review focuses on recent advances in non-invasive magnetic resonance imaging and spectroscopy for quantifying total body and regional adiposity, mapping adipose tissue distribution, and evaluating selected metabolic disturbances in children. The aim is to provide an investigator-focused overview of magnetic resonance methods for use in the study of pediatric body composition and metabolism. Recent findings Whole body axial images can be rapidly acquired on most clinical magnetic resonance imaging scanners. The images can then be semi-automatically segmented into subcutaneous, visceral, and intramuscular adipose tissue. Specific pediatric studies of errors related to slice gap and number are available. The acquisition of scans in healthy and premature infants is now feasible with recent technological advances. Spectroscopic, Dixon, and other approaches can be used to quantify the lipid content of liver, skeletal muscle, and other organs. Protocol selection is based on factors such as subject age and cost. Particular attention should be directed towards identification of landmarks in growth studies. Recent advances promise to reduce the requirement of subjects to remain motionless for relatively long periods. Summary Magnetic resonance imaging and spectroscopy are safe, practical, and widely available methods for phenotyping adiposity in children that open new opportunities for metabolism and nutritional research. PMID:16205458

  12. 3D positional control of magnetic levitation system using adaptive control: improvement of positioning control in horizontal plane

    NASA Astrophysics Data System (ADS)

    Nishino, Toshimasa; Fujitani, Yasuhiro; Kato, Norihiko; Tsuda, Naoaki; Nomura, Yoshihiko; Matsui, Hirokazu

    2012-01-01

    The objective of this paper is to establish a technique that levitates and conveys a hand, a kind of micro-robot, by applying magnetic forces: the hand is assumed to have a function of holding and detaching the objects. The equipment to be used in our experiments consists of four pole-pieces of electromagnets, and is expected to work as a 4DOF drive unit within some restricted range of 3D space: the three DOF are corresponding to 3D positional control and the remaining one DOF, rotational oscillation damping control. Having used the same equipment, Khamesee et al. had manipulated the impressed voltages on the four electric magnetics by a PID controller by the use of the feedback signal of the hand's 3D position, the controlled variable. However, in this system, there were some problems remaining: in the horizontal direction, when translating the hand out of restricted region, positional control performance was suddenly degraded. The authors propose a method to apply an adaptive control to the horizontal directional control. It is expected that the technique to be presented in this paper contributes not only to the improvement of the response characteristic but also to widening the applicable range in the horizontal directional control.

  13. A 3-D Magnetic Analysis of a Stirling Convertor Linear Alternator Under Load

    NASA Technical Reports Server (NTRS)

    Geng, Steven M.; Schwarze, Gene E.; Niedra, Janis M.; Regan, Timothy F.

    2001-01-01

    The NASA Glenn Research Center (GRC), the Department of Energy (DOE), and the Stirling Technology Company (STC) are developing Stirling convertors for Stirling Radioisotope Power Systems (SRPS) to provide electrical power for future NASA deep space missions. STC is developing the 55-We Technology Demonstration Convertor (TDC) under contract to DOE. Of critical importance to the successful development of the Stirling convertor for space power applications is the development of a lightweight and highly efficient linear alternator. This paper presents a 3-dimensional finite element method (FEM) approach for evaluating Stirling convertor linear alternators. The model extends a magnetostatic analysis previously reported at the 35th Intersociety Energy Conversion Engineering Conference (IECEC) to include the effects of the load current. STC's 55-We linear alternator design was selected to validate the model. Spatial plots of magnetic field strength (H) are presented in the region of the exciting permanent magnets. The margin for permanent magnet demagnetization is calculated at the expected magnet operating temperature for the near earth environment and for various average magnet temperatures. These thermal conditions were selected to represent a worst-case condition for the planned deep space missions. This paper presents plots that identify regions of high H where the potential to alter the magnetic moment of the magnets exists.

  14. Reproducing electric field observations during magnetic storms by means of rigorous 3-D modelling and distortion matrix co-estimation

    NASA Astrophysics Data System (ADS)

    Püthe, Christoph; Manoj, Chandrasekharan; Kuvshinov, Alexey

    2014-12-01

    Electric fields induced in the conducting Earth by geomagnetic disturbances drive currents in power transmission grids, telecommunication lines or buried pipelines, which can cause service disruptions. A key step in the prediction of the hazard to technological systems during magnetic storms is the calculation of the geoelectric field. To address this issue for mid-latitude regions, we revisit a method that involves 3-D modelling of induction processes in a heterogeneous Earth and the construction of a magnetospheric source model described by low-degree spherical harmonics from observatory magnetic data. The actual electric field, however, is known to be perturbed by galvanic effects, arising from very local near-surface heterogeneities or topography, which cannot be included in the model. Galvanic effects are commonly accounted for with a real-valued time-independent distortion matrix, which linearly relates measured and modelled electric fields. Using data of six magnetic storms that occurred between 2000 and 2003, we estimate distortion matrices for observatory sites onshore and on the ocean bottom. Reliable estimates are obtained, and the modellings are found to explain up to 90% of the measurements. We further find that 3-D modelling is crucial for a correct separation of galvanic and inductive effects and a precise prediction of the shape of electric field time series during magnetic storms. Since the method relies on precomputed responses of a 3-D Earth to geomagnetic disturbances, which can be recycled for each storm, the required computational resources are negligible. Our approach is thus suitable for real-time prediction of geomagnetically induced currents by combining it with reliable forecasts of the source field.

  15. A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration.

    PubMed

    Saeed, Aram; Francini, Nora; White, Lisa; Dixon, James; Gould, Toby; Rashidi, Hassan; Al Ghanami, Racha Cheikh; Hruschka, Veronika; Redl, Heinz; Saunders, Brian R; Alexander, Cameron; Shakesheff, Kevin M

    2015-01-27

    A dual thermoresponsive and magnetic colloidal gel matrix is described for enhanced stem-cell culture. The combined properties of the material allow enzyme-free passaging and expansion of mesenchymal stem cells, as well as isolation of cells postculture by the simple process of lowering the temperature and applying an external magnetic field. The colloidal gel can be reconfigured with thermal and magnetic stimuli to allow patterning of cells in discrete zones and to control movement of cells within the porous matrix during culture.

  16. Magnetic resonance force microscopy and a solid state quantum computer.

    SciTech Connect

    Pelekhov, D. V.; Martin, I.; Suter, A.; Reagor, D. W.; Hammel, P. C.

    2001-01-01

    A Quantum Computer (QC) is a device that utilizes the principles of Quantum Mechanics to perform computations. Such a machine would be capable of accomplishing tasks not achievable by means of any conventional digital computer, for instance factoring large numbers. Currently it appears that the QC architecture based on an array of spin quantum bits (qubits) embedded in a solid-state matrix is one of the most promising approaches to fabrication of a scalable QC. However, the fabrication and operation of a Solid State Quantum Computer (SSQC) presents very formidable challenges; primary amongst these are: (1) the characterization and control of the fabrication process of the device during its construction and (2) the readout of the computational result. Magnetic Resonance Force Microscopy (MRFM)--a novel scanning probe technique based on mechanical detection of magnetic resonance-provides an attractive means of addressing these requirements. The sensitivity of the MRFM significantly exceeds that of conventional magnetic resonance measurement methods, and it has the potential for single electron spin detection. Moreover, the MRFM is capable of true 3D subsurface imaging. These features will make MRFM an invaluable tool for the implementation of a spin-based QC. Here we present the general principles of MRFM operation, the current status of its development and indicate future directions for its improvement.

  17. Magnetic material arrangement in oriented termites: a magnetic resonance study

    NASA Astrophysics Data System (ADS)

    Alves, O. C.; Wajnberg, E.; de Oliveira, J. F.; Esquivel, D. M. S.

    2004-06-01

    Temperature dependence of the magnetic resonance is used to study the magnetic material in oriented Neocapritermes opacus (N.o.) termite, the only prey of the migratory ant Pachycondyla marginata (P.m.). A broad line in the g=2 region, associated to isolated nanoparticles shows that at least 97% of the magnetic material is in the termite's body (abdomen + thorax). From the temperature dependence of the resonant field and from the spectral linewidths, we estimate the existence of magnetic nanoparticles 18.5 ± 0.3 nm in diameter and an effective magnetic anisotropy constant, Keff between 2.1 and 3.2 × 10 4 erg/cm 3. A sudden change in the double integrated spectra at about 100 K for N.o. with the long body axis oriented perpendicular to the magnetic field can be attributed to the Verwey transition, and suggests an organized film-like particle system.

  18. Electric current variations and 3D magnetic configuration of coronal jets

    NASA Astrophysics Data System (ADS)

    Schmieder, Brigitte; Harra, Louise K.; Aulanier, Guillaume; Guo, Yang; Demoulin, Pascal; Moreno-Insertis, Fernando, , Prof

    Coronal jets (EUV) were observed by SDO/AIA on September 17, 2010. HMI and THEMIS measured the vector magnetic field from which we derived the magnetic flux, the phostospheric velocity and the vertical electric current. The magnetic configuration was computed with a non linear force-free approach. The phostospheric current pattern of the recurrent jets were associated with the quasi-separatrix layers deduced from the magnetic extrapolation. The large twisted near-by Eiffel-tower-shape jet was also caused by reconnection in current layers containing a null point. This jet cannot be classified precisely within either the quiescent or the blowout jet types. We will show the importance of the existence of bald patches in the low atmosphere

  19. 3D field calculation of the GEM prototype magnet and comparison with measurements

    SciTech Connect

    Lari, R.J.

    1983-10-28

    The proposed 4 GeV Electron Microtron (GEM) is designed to fill the existing buildings left vacant by the demise of the Zero Gradient Synchrotron (ZGS) accelerator. One of the six large dipole magnets is shown as well as the first 10 electron orbits. A 3-orbit prototype magnet has been built. The stepped edge of the magnet is to keep the beam exiting perpendicular to the pole. The end guards that wrap around the main coils are joined together by the 3 shield plates. The auxiliary coils are needed to keep the end guards and shield plates from saturating. A 0.3 cm Purcell filter air gap exists between the pole and the yoke. Can anyone question this being a truly three-dimensional magnetostatic problem. The computer program TOSCA, developed at the Rutherford Appleton Laboratory by the Computing Applications Group, was used to calculate this magnet and the results have been compared with measurements.

  20. 3-D RPIC Simulations of Relativistic Jets: Particle Acceleration, Magnetic Field Generation, and Emission

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Mizuno, Y.; Hardee, P.; Hededal, C. B.; Fishman, G. J.

    2006-01-01

    Recent PIC simulations using injected relativistic electron-ion (electro-positron) jets into ambient plasmas show that acceleration occurs in relativistic shocks. The Weibel instability created in shocks is responsible for particle acceleration, and generation and amplification of highly inhomogeneous, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection in relativistic jets. The "jitter" radiation from deflected electrons has different properties than the synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understand the complex time evolution and spectral structure in relativistic jets and gamma-ray bursts. We will present recent PIC simulations which show particle acceleration and magnetic field generation. We will also calculate associated self-consistent emission from relativistic shocks.

  1. 3D magnetic interactions of stars with their close-in planets

    NASA Astrophysics Data System (ADS)

    Strugarek, Antoine; Brun, Allan Sacha; Matt, Sean; Réville, Victor

    2015-08-01

    Close-in planets generally orbit in a sub-alfv ´enic stellar wind, where the perturbations they excite in the corona are able to travel upwind to the stellar surface and potentially induce observable phenomena. The effective connection between the planet and its host takes the form of two Aflv ´en wings. Depending on the topology of the planetary and stellar magnetic fields, the rotation profile of the corona, and the orbital parameters, it is possible that none, one, or the two Aflv ´en wings connect together the star and the planet.We explore the formation and sustainment of Alfv ´en wings in global three dimensional simulations under the magneto-hydrodynamic formalism with the PLUTO code. We model the stellar wind of a typical cool star in which a close-in orbiting planet is introduced as a boundary condition. By varying the magnetic topologies of the planetary and stellar magnetic fields, we explore the variety of Alfv ´en wings that can develop and quantify the Poynting flux flowing through those wings. We thus provide estimates of the amount of magnetic energy these magnetic interactions can channel to the lower corona. We also quantify the phase and latitude offsets that can be expected between the planetary subpoint on the stellar surface and the actual location where energy is deposited. We summarize the typical situations (in terms of magnetic topology, stellar type, and orbital parameters) where the star-planet magnetic interaction could trigger observable flares. We conclude by extending our results to the cases of more complex, non-axisymmetric topologies of the observed magnetic fields for a few particular stars.

  2. 3D-Printed Permanent Magnets Outperform Conventional Versions, Conserve Rare Materials

    SciTech Connect

    Paranthaman, Parans

    2016-11-01

    Researchers at the Department of Energy’s Oak Ridge National Laboratory have demonstrated that permanent magnets produced by additive manufacturing can outperform bonded magnets made using traditional techniques while conserving critical materials. The project is part of DOE’s Critical Materials Institute (CMI), which seeks ways to eliminate and reduce reliance on rare earth metals and other materials critical to the success of clean energy technologies.

  3. 3D-Printed Permanent Magnets Outperform Conventional Versions, Conserve Rare Materials

    ScienceCinema

    Paranthaman, Parans

    2016-11-23

    Researchers at the Department of Energy’s Oak Ridge National Laboratory have demonstrated that permanent magnets produced by additive manufacturing can outperform bonded magnets made using traditional techniques while conserving critical materials. The project is part of DOE’s Critical Materials Institute (CMI), which seeks ways to eliminate and reduce reliance on rare earth metals and other materials critical to the success of clean energy technologies.

  4. Single crystalline cylindrical nanowires – toward dense 3D arrays of magnetic vortices

    PubMed Central

    Ivanov, Yurii P.; Chuvilin, Andrey; Vivas, Laura G.; Kosel, Jurgen; Chubykalo-Fesenko, Oksana; Vázquez, Manuel

    2016-01-01

    Magnetic vortex-based media have recently been proposed for several applications of nanotechnology; however, because lithography is typically used for their preparation, their low-cost, large-scale fabrication is a challenge. One solution may be to use arrays of densely packed cobalt nanowires that have been efficiently fabricated by electrodeposition. In this work, we present this type of nanoscale magnetic structures that can hold multiple stable magnetic vortex domains at remanence with different chiralities. The stable vortex state is observed in arrays of monocrystalline cobalt nanowires with diameters as small as 45 nm and lengths longer than 200 nm with vanishing magnetic cross talk between closely packed neighboring wires in the array. Lorentz microscopy, electron holography and magnetic force microscopy, supported by micromagnetic simulations, show that the structure of the vortex state can be adjusted by varying the aspect ratio of the nanowires. The data we present here introduce a route toward the concept of 3-dimensional vortex-based magnetic memories. PMID:27030143

  5. Single crystalline cylindrical nanowires – toward dense 3D arrays of magnetic vortices

    NASA Astrophysics Data System (ADS)

    Ivanov, Yurii P.; Chuvilin, Andrey; Vivas, Laura G.; Kosel, Jurgen; Chubykalo-Fesenko, Oksana; Vázquez, Manuel

    2016-03-01

    Magnetic vortex-based media have recently been proposed for several applications of nanotechnology; however, because lithography is typically used for their preparation, their low-cost, large-scale fabrication is a challenge. One solution may be to use arrays of densely packed cobalt nanowires that have been efficiently fabricated by electrodeposition. In this work, we present this type of nanoscale magnetic structures that can hold multiple stable magnetic vortex domains at remanence with different chiralities. The stable vortex state is observed in arrays of monocrystalline cobalt nanowires with diameters as small as 45 nm and lengths longer than 200 nm with vanishing magnetic cross talk between closely packed neighboring wires in the array. Lorentz microscopy, electron holography and magnetic force microscopy, supported by micromagnetic simulations, show that the structure of the vortex state can be adjusted by varying the aspect ratio of the nanowires. The data we present here introduce a route toward the concept of 3-dimensional vortex-based magnetic memories.

  6. CONTINUUM INTENSITY AND [O i] SPECTRAL LINE PROFILES IN SOLAR 3D PHOTOSPHERIC MODELS: THE EFFECT OF MAGNETIC FIELDS

    SciTech Connect

    Fabbian, D.; Moreno-Insertis, F. E-mail: fmi@iac.es

    2015-04-01

    The importance of magnetic fields in three-dimensional (3D) magnetoconvection models of the Sun’s photosphere is investigated in terms of their influence on the continuum intensity at different viewing inclination angles and on the intensity profile of two [O i] spectral lines. We use the RH numerical radiative transfer code to perform a posteriori spectral synthesis on the same time series of magnetoconvection models used in our publications on the effect of magnetic fields on abundance determination. We obtain a good match of the synthetic disk-center continuum intensity to the absolute continuum values from the Fourier Transform Spectrometer (FTS) observational spectrum; the match of the center-to-limb variation synthetic data to observations is also good, thanks, in part, to the 3D radiation transfer capabilities of the RH code. The different levels of magnetic flux in the numerical time series do not modify the quality of the match. Concerning the targeted [O i] spectral lines, we find, instead, that magnetic fields lead to nonnegligible changes in the synthetic spectrum, with larger average magnetic flux causing both of the lines to become noticeably weaker. The photospheric oxygen abundance that one would derive if instead using nonmagnetic numerical models would thus be lower by a few to several centidex. The inclusion of magnetic fields is confirmed to be important for improving the current modeling of the Sun, here in particular in terms of spectral line formation and of deriving consistent chemical abundances. These results may shed further light on the still controversial issue regarding the precise value of the solar oxygen abundance.

  7. Reproducing Electric Field Observations during Magnetic Storms by means of Rigorous 3-D Modelling and Distortion Matrix Co-estimation

    NASA Astrophysics Data System (ADS)

    Püthe, Christoph; Manoj, Chandrasekharan; Kuvshinov, Alexey

    2015-04-01

    Electric fields induced in the conducting Earth during magnetic storms drive currents in power transmission grids, telecommunication lines or buried pipelines. These geomagnetically induced currents (GIC) can cause severe service disruptions. The prediction of GIC is thus of great importance for public and industry. A key step in the prediction of the hazard to technological systems during magnetic storms is the calculation of the geoelectric field. To address this issue for mid-latitude regions, we developed a method that involves 3-D modelling of induction processes in a heterogeneous Earth and the construction of a model of the magnetospheric source. The latter is described by low-degree spherical harmonics; its temporal evolution is derived from observatory magnetic data. Time series of the electric field can be computed for every location on Earth's surface. The actual electric field however is known to be perturbed by galvanic effects, arising from very local near-surface heterogeneities or topography, which cannot be included in the conductivity model. Galvanic effects are commonly accounted for with a real-valued time-independent distortion matrix, which linearly relates measured and computed electric fields. Using data of various magnetic storms that occurred between 2000 and 2003, we estimated distortion matrices for observatory sites onshore and on the ocean bottom. Strong correlations between modellings and measurements validate our method. The distortion matrix estimates prove to be reliable, as they are accurately reproduced for different magnetic storms. We further show that 3-D modelling is crucial for a correct separation of galvanic and inductive effects and a precise prediction of electric field time series during magnetic storms. Since the required computational resources are negligible, our approach is suitable for a real-time prediction of GIC. For this purpose, a reliable forecast of the source field, e.g. based on data from satellites

  8. 3D effects of edge magnetic field configuration on divertor/scrape-off layer transport and optimization possibilities for a future reactor

    NASA Astrophysics Data System (ADS)

    Kobayashi, M.; Xu, Y.; Ida, K.; Corre, Y.; Feng, Y.; Schmitz, O.; Frerichs, H.; Tabares, F. L.; Evans, T. E.; Coenen, J. W.; Liang, Y.; Bader, A.; Itoh, K.; Yamada, H.; Ghendrih, Ph.; Ciraolo, G.; Tafalla, D.; Lopez-Fraguas, A.; Guo, H. Y.; Cui, Z. Y.; Reiter, D.; Asakura, N.; Wenzel, U.; Morita, S.; Ohno, N.; Peterson, B. J.; Masuzaki, S.

    2015-10-01

    This paper assesses the three-dimensional (3D) effects of the edge magnetic field structure on divertor/scrape-off layer transport, based on an inter-machine comparison of experimental data and on the recent progress of 3D edge transport simulation. The 3D effects are elucidated as a consequence of competition between transports parallel (\\parallel ) and perpendicular (\\bot ) to the magnetic field, in open field lines cut by divertor plates, or in magnetic islands. The competition has strong impacts on divertor functions, such as determination of the divertor density regime, impurity screening and detachment control. The effects of magnetic perturbation on the edge electric field and turbulent transport are also discussed. Parameterization to measure the 3D effects on the edge transport is attempted for the individual divertor functions. Based on the suggested key parameters, an operation domain of the 3D divertor configuration is discussed for future devices.

  9. Gadofosveset-enhanced magnetic resonance angiography

    PubMed Central

    Goyen, Mathias

    2008-01-01

    Gadofosveset (Vasovist®, Bayer Schering Pharma AG, Berlin/Germany) is the first intravascular contrast agent approved for use with magnetic resonance angiography in the European Union, Switzerland, Turkey, Canada, and Australia. Gadofosveset reversibly binds to albumin providing extended intravascular enhancement compared wth existing extracellular magnetic resonance contrast agents. Prior to approval, gadofosveset underwent extensive testing to evaluate the safety and efficacy of the drug; the clinical trials show that gadofosveset-enhanced magnetic resonance angiography (MRA) is safe and well tolerated in patients with vascular disease and effective for the detection of vascular stenosis and aneurysms gadofosveset has the potential to open new horizons in diagnostic MRA by increasing the spatial resolution and the robustness of MRA examinations and facilitating the examination of multiple vascular beds. PMID:18629367

  10. Magnetic resonance imaging of the body

    SciTech Connect

    Higgins, C.B.; Hricak, H.

    1987-01-01

    This text provides reference to magnetic resonance imaging (MRI) of the body. Beginning with explanatory chapters on the physics, instrumentation, and interpretation of MRI, it proceeds to the normal anatomy of the neck, thorax, abdomen, and pelvis. Other chapters cover magnetic resonance imaging of blood flow, the larynx, the lymph nodes, and the spine, as well as MRI in obstetrics. The text features detailed coverage of magnetic resonance imaging of numerous disorders and disease states, including neck disease, thoracic disease; breast disease; congenital and acquired heart disease; vascular disease; diseases of the liver, pancreas, and spleen; diseases of the kidney, adrenals, and retroperitoneum; diseases of the male and female pelvis; and musculoskeletal diseases. Chapters on the biological and environmental hazards of MRI, the current clinical status of MRI in comparison to other imaging modalities, and economic considerations are also included.

  11. Tutte polynomial in functional magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    García-Castillón, Marlly V.

    2015-09-01

    Methods of graph theory are applied to the processing of functional magnetic resonance images. Specifically the Tutte polynomial is used to analyze such kind of images. Functional Magnetic Resonance Imaging provide us connectivity networks in the brain which are represented by graphs and the Tutte polynomial will be applied. The problem of computing the Tutte polynomial for a given graph is #P-hard even for planar graphs. For a practical application the maple packages "GraphTheory" and "SpecialGraphs" will be used. We will consider certain diagram which is depicting functional connectivity, specifically between frontal and posterior areas, in autism during an inferential text comprehension task. The Tutte polynomial for the resulting neural networks will be computed and some numerical invariants for such network will be obtained. Our results show that the Tutte polynomial is a powerful tool to analyze and characterize the networks obtained from functional magnetic resonance imaging.

  12. Magnetic Resonance Imaging (MRI) - Spine

    MedlinePlus

    ... magnetic field of the MRI unit, metal and electronic items are not allowed in the exam room. ... tell the technologist if you have medical or electronic devices in your body. These objects may interfere ...

  13. Children's (Pediatric) Magnetic Resonance Imaging

    MedlinePlus

    ... if your child has any implanted medical or electronic devices. Inform your doctor and the technologist prior ... magnetic field of the MRI unit, metal and electronic items are not allowed in the exam room. ...

  14. Magnetic Resonance Imaging (MRI) -- Head

    MedlinePlus

    ... magnetic field of the MRI unit, metal and electronic items are not allowed in the exam room. ... tell the technologist if you have medical or electronic devices in your body. These objects may interfere ...

  15. Magnetic Resonance Imaging (MRI) Safety

    MedlinePlus

    ... by a receiver within the MR scanner. The signals are specially characterized using the rapidly changing magnetic field, and, with the help of computer processing, images of tissues are created as "slices" that ...

  16. Interpretation of gravity and magnetic data with geological constraints for 3D structure of the Thuringian Basin, Germany

    NASA Astrophysics Data System (ADS)

    Prutkin, Ilya; Vajda, Peter; Jahr, Thomas; Bleibinhaus, Florian; Novák, Pavel; Tenzer, Robert

    2017-01-01

    We apply a novel method for the separation of potential field sources and their 3D inversion at the regional study area of Thuringian Basin in central Germany. The gravity and magnetic data are separated into long, medium and short wavelengths and then inverted separately. The main goal is to study uniqueness of the solution and its stability in all numerical steps of the interpretation process and to demonstrate, how geological constraints can diminish the degree of non-uniqueness by the interpretation of the gravity and magnetic anomalies. Our numerical experiments with medium wavelengths reveal that if we explain negative anomalies with the topography of near-surface layers, the obtained solution is not supported by borehole data. These negative anomalies are thus explained by restricted bodies (granitic intrusions) at the depths from 4 down to 10 km. These bodies are located above a density interface with topography at the depth of approximately 10 km. The 3D inversion of magnetic data (at short wavelengths) allows investigating a detailed structure of the upper boundary of the crystalline basement: two uplifts in the depths between 2.0 and 0.7 km are found. By using the residual negative anomalies we further study the salt tectonics, showing that the geometry of a salt pillow with a thickness of approximately 200 m closely agrees with borehole data.

  17. RKKY-like contributions to the magnetic anisotropy energy: 3 d adatoms on Pt(111) surface

    NASA Astrophysics Data System (ADS)

    Bouhassoune, Mohammmed; Dias, Manuel dos Santos; Zimmermann, Bernd; Dederichs, Peter H.; Lounis, Samir

    2016-09-01

    The magnetic anisotropy energy defines the energy barrier that stabilizes a magnetic moment. Utilizing density-functional-theory-based simulations and analytical formulations, we establish that this barrier is strongly modified by long-range contributions very similar to Friedel oscillations and Rudermann-Kittel-Kasuya-Yosida interactions. Thus, oscillations are expected and observed, with different decaying factors and highly anisotropic in realistic materials, which can switch nontrivially the sign of the magnetic anisotropy energy. This behavior is general, and for illustration we address the transition-metal adatoms, Cr, Mn, Fe, and Co deposited on a Pt(111) surface. We explain, in particular, the mechanisms leading to the strong site dependence of the magnetic anisotropy energy observed for Fe adatoms on a Pt(111) surface as revealed previously via first-principles-based simulations and inelastic scanning tunneling spectroscopy [A. A. Khajetoorians et al., Phys. Rev. Lett. 111, 157204 (2013), 10.1103/PhysRevLett.111.157204]. The same mechanisms are probably active for the site dependence of the magnetic anisotropy energy obtained for Fe adatoms on Pd or Rh(111) surfaces and for Co adatoms on a Rh(111) surface [P. Blonski et al., Phys. Rev. B 81, 104426 (2010), 10.1103/PhysRevB.81.104426].

  18. A novel method for assessing the 3-D orientation accuracy of inertial/magnetic sensors.

    PubMed

    Faber, Gert S; Chang, Chien-Chi; Rizun, Peter; Dennerlein, Jack T

    2013-10-18

    A novel method for assessing the accuracy of inertial/magnetic sensors is presented. The method, referred to as the "residual matrix" method, is advantageous because it decouples the sensor's error with respect to Earth's gravity vector (attitude residual error: pitch and roll) from the sensor's error with respect to magnetic north (heading residual error), while remaining insensitive to singularity problems when the second Euler rotation is close to ±90°. As a demonstration, the accuracy of an inertial/magnetic sensor mounted to a participant's forearm was evaluated during a reaching task in a laboratory. Sensor orientation was measured internally (by the inertial/magnetic sensor) and externally using an optoelectronic measurement system with a marker cluster rigidly attached to the sensor's enclosure. Roll, pitch and heading residuals were calculated using the proposed novel method, as well as using a common orientation assessment method where the residuals are defined as the difference between the Euler angles measured by the inertial sensor and those measured by the optoelectronic system. Using the proposed residual matrix method, the roll and pitch residuals remained less than 1° and, as expected, no statistically significant difference between these two measures of attitude accuracy was found; the heading residuals were significantly larger than the attitude residuals but remained below 2°. Using the direct Euler angle comparison method, the residuals were in general larger due to singularity issues, and the expected significant difference between inertial/magnetic sensor attitude and heading accuracy was not present.

  19. 3D hybrid simulations of the plasma penetration across a magnetic field

    NASA Astrophysics Data System (ADS)

    Omelchenko, Yuri

    2016-10-01

    The expansion of hot dense plasmas across ambient magnetic fields in physical systems with spatial scales comparable to the ion gyro and inertial lengths is of great interest to space physics and fusion. This work presents results from recent three-dimensional hybrid simulations (kinetic ions, fluid electrons) of experiments at the LAPD and Nevada Terawatt Facility where short-pulse lasers are used to ablate solid targets to produce plasmas that expand across external magnetic fields. The first simulation recreates flutelike density striations observed at the leading edge of the carbon plasma and predicts an early destruction of the magnetic cavity in agreement with experimental evidence. In the second simulation the plasma contains protons and carbon ions produced during the ablation of a polyethylene target. A mechanism is demonstrated that allows protons to penetrate the magnetic field in the form of a collimated flow while the carbon ion component forms a supporting magnetic structure. The role of ion kinetic and Hall effects in creating an electric field responsible for plasma transport is discussed and results are compared to experimental data. The hybrid simulations are performed with a massively parallel hybrid code, HYPERS that advances fields and particles asynchronously on time scales determined by local physical and geometric properties. Supported by US DOE Award DE-SC0012345.

  20. Locating magnetic reconnection x-lines in 3D PIC simulations

    NASA Astrophysics Data System (ADS)

    Olson, D. K.; Dorelli, J.; Daughton, W. S.; Karimabadi, H.

    2013-12-01

    In a three-dimensional PIC simulation of turbulent magnetic reconnection, a reconnection 'X-line' can be identified as a separator in the magnetic topology. From this x-line, it is possible to compute the reconnection rate by evaluating the line integral of the electric field along the separator. This technique is used in a reconnection simulation of a symmetric Harris sheet driven by inflow at the upstream boundaries with a strong guide field (such that the magnetic field is non-vanishing everywhere and there are no magnetic nulls). The results of this analysis are compared to the General Magnetic Reconnection theory (GMR) [Hesse and Schindler, 1998], showing that in this symmetric case GMR agrees with our topological approach to finding the location of the x-line. The parallel electric field is non-trivial along the entire length of the x-line, however, suggesting that the reconnection diffusion region cannot be identified by local measures of the breakdown of ideal MHD alone. We discuss the implications of these results for NASA's upcoming Magnetospheric Multiscale mission.

  1. Granular convection observed by magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Ehrichs, E. E.; Jaeger, H. M.; Karczmar, Greg S.; Knight, James B.; Kuperman, Vadim Yu.; Nagel, Sidney R.

    1995-03-01

    Vibrations in a granular material can spontaneously produce convection rolls reminiscent of those seen in fluids. Magnetic resonance imaging provides a sensitive and noninvasive probe for the detection of these convection currents, which have otherwise been difficult to observe. A magnetic resonance imaging study of convection in a column of poppy seeds yielded data about the detailed shape of the convection rolls and the depth dependence of the convection velocity. The velocity was found to decrease exponentially with depth; a simple model for this behavior is presented here.

  2. Granular convection observed by magnetic resonance imaging

    SciTech Connect

    Ehrichs, E.E.; Jaeger, H.M.; Knight, J.B.; Nagel, S.R.; Karczmar, G.S.; Kuperman, V.Yu.

    1995-03-17

    Vibrations in a granular material can spontaneously produce convection rolls reminiscent of those seen in fluids. Magnetic resonance imaging provides a sensitive and noninvasive probe for the detection of these convection currents, which have otherwise been difficult to observe. A magnetic resonance imaging study of convection in a column of poppy seeds yielded data about the detailed shape of the convection rolls and the depth dependence of the convection velocity. The velocity was found to decrease exponentially with depth; a simple model for this behavior is presented here. 31 refs., 4 figs.

  3. Magnetic resonance neurography of the brachial plexus

    PubMed Central

    Upadhyaya, Vaishali; Upadhyaya, Divya Narain; Kumar, Adarsh; Pandey, Ashok Kumar; Gujral, Ratni; Singh, Arun Kumar

    2015-01-01

    Magnetic Resonance Imaging (MRI) is being increasingly recognised all over the world as the imaging modality of choice for brachial plexus and peripheral nerve lesions. Recent refinements in MRI protocols have helped in imaging nerve tissue with greater clarity thereby helping in the identification, localisation and classification of nerve lesions with greater confidence than was possible till now. This article on Magnetic Resonance Neurography (MRN) is based on the authors’ experience of imaging the brachial plexus and peripheral nerves using these protocols over the last several years. PMID:26424974

  4. Cardiovascular magnetic resonance of anomalous coronary arteries.

    PubMed

    Varghese, Anitha; Keegan, Jennifer; Pennell, Dudley J

    2005-09-01

    Cardiovascular magnetic resonance of anomalous coronary arteries is a class I indication. The term anomalous coronary artery encompasses those with an abnormal origin (from the incorrect sinus, too-high or too-low from the correct sinus, or from the pulmonary artery) and/or number of ostia. Their clinical significance results from the increased risk of myocardial infarction and sudden cardiac death associated with those traversing an interarterial course between the aorta and main pulmonary artery/right ventricular outflow tract. In this article, we review the role and practice of cardiovascular magnetic resonance in this field.

  5. Integrated imaging of neuromagnetic reconstructions and morphological magnetic resonance data.

    PubMed

    Kullmann, W H; Fuchs, M

    1991-01-01

    New neuromagnetic imaging methods provide spatial information about the functional electrical properties of complex current distributions in the human brain. For practical use in medical diagnosis a combination of the abstract neuromagnetic imaging results with magnetic resonance (MR) or computed tomography (CT) images of the morphology is required. The biomagnetic images can be overlayed onto three-dimensional morphological images with spatially arbitrary selectable slices, calculated from conventional 2D data. For the current reconstruction the 3D images furthermore provide a priori information about the conductor geometry. A combination of current source density calculations and linear estimation methods for handling the inverse magnetic problem allows quick imaging of impressed current source density in arbitrary volume conductors.

  6. Global magnetosphere-like 3D structure formation in kinetics by hot magnetized plasma flow characterized by shape of the particle distribution function

    NASA Astrophysics Data System (ADS)

    Gubchenko, Vladimir

    The task was to provide an analytical elementary magnetosphere-like model in kinetics for verification of the 3D EM PIC codes created for space/aerospace and HED plasmas applications. Kinetic approach versus cold MHD approach takes into account different behavior in the EM fields of resonant and non resonant particles in the velocity phase space, which appears via shape characteristics of the particle velocity distribution function (PVDF) and via the spatial dispersion effect forming the collisionless dissipation in the EM fields. The external flow is a hot collisionless plasma characterized by the particle velocity distribution function (PVDF) with different shapes: Maxwellian, kappa, etc. The flow is in a “hot regime”: it can be supersonic but its velocity remains less the thermal velocity of the electrons. The “internal” part of the magnetosphere formed by trapped particles is the prescribed 3D stationary magnetization considered as a spherical “quasiparticle” with internal magnetodipole and toroidal moments represented as a broadband EM driver. We obtain after the linearization of Vlasov/Maxwell equations a self-consistent 3D large scale kinetic solution of the classic problem. Namely, we: model the “outer” part of the magnetosphere formed by external hot plasma flow of the flyby particles. Solution of the Vlasov equation expressed via a tensor of dielectric permittivity of nonmagnetized and magnetized flowing plasma. Here, we obtain the direct kinetic dissipative effect of the magnetotail formation and the opposite diamagnetic effect of the magnetosphere “dipolization”. We get MHD wave cone in flow magnetized by external guiding magnetic (GM) field. Magnetosphere in our consideration is a 3D dissipative “wave” package structure of the skinned EM fields formed by the “waves” excited at frequency bands where we obtain negative values and singularities (resonances) of squared EM refractive index of the cold plasma. The hot regime

  7. Magnetic force microscopy using tip magnetization modulated by ferromagnetic resonance.

    PubMed

    Arima, Eiji; Naitoh, Yoshitaka; Li, Yan Jun; Yoshimura, Satoru; Saito, Hitoshi; Nomura, Hikaru; Nakatani, Ryoichi; Sugawara, Yasuhiro

    2015-03-27

    In magnetic force microscopy (MFM), the tip-sample distance should be reduced to analyze the microscopic magnetic domain structure with high spatial resolution. However, achieving a small tip-sample distance has been difficult because of superimposition of interaction forces such as van der Waals and electrostatic forces induced by the sample surface. In this study, we propose a new method of MFM using ferromagnetic resonance (FMR) to extract only the magnetic field near the sample surface. In this method, the magnetization of a magnetic cantilever is modulated by FMR to separate the magnetic field and topographic structure. We demonstrate the modulation of the magnetization of the cantilever and the identification of the polarities of a perpendicular magnetic medium.

  8. The effect of anisotropic heat transport on magnetic islands in 3-D configurations

    SciTech Connect

    Schlutt, M. G.; Hegna, C. C.

    2012-08-15

    An analytic theory of nonlinear pressure-induced magnetic island formation using a boundary layer analysis is presented. This theory extends previous work by including the effects of finite parallel heat transport and is applicable to general three dimensional magnetic configurations. In this work, particular attention is paid to the role of finite parallel heat conduction in the context of pressure-induced island physics. It is found that localized currents that require self-consistent deformation of the pressure profile, such as resistive interchange and bootstrap currents, are attenuated by finite parallel heat conduction when the magnetic islands are sufficiently small. However, these anisotropic effects do not change saturated island widths caused by Pfirsch-Schlueter current effects. Implications for finite pressure-induced island healing are discussed.

  9. Non-magnetic photospheric bright points in 3D simulations of the solar atmosphere

    NASA Astrophysics Data System (ADS)

    Calvo, F.; Steiner, O.; Freytag, B.

    2016-11-01

    Context. Small-scale bright features in the photosphere of the Sun, such as faculae or G-band bright points, appear in connection with small-scale magnetic flux concentrations. Aims: Here we report on a new class of photospheric bright points that are free of magnetic fields. So far, these are visible in numerical simulations only. We explore conditions required for their observational detection. Methods: Numerical radiation (magneto-)hydrodynamic simulations of the near-surface layers of the Sun were carried out. The magnetic field-free simulations show tiny bright points, reminiscent of magnetic bright points, only smaller. A simple toy model for these non-magnetic bright points (nMBPs) was established that serves as a base for the development of an algorithm for their automatic detection. Basic physical properties of 357 detected nMBPs were extracted and statistically evaluated. We produced synthetic intensity maps that mimic observations with various solar telescopes to obtain hints on their detectability. Results: The nMBPs of the simulations show a mean bolometric intensity contrast with respect to their intergranular surroundings of approximately 20%, a size of 60-80 km, and the isosurface of optical depth unity is at their location depressed by 80-100 km. They are caused by swirling downdrafts that provide, by means of the centripetal force, the necessary pressure gradient for the formation of a funnel of reduced mass density that reaches from the subsurface layers into the photosphere. Similar, frequently occurring funnels that do not reach into the photosphere, do not produce bright points. Conclusions: Non-magnetic bright points are the observable manifestation of vertically extending vortices (vortex tubes) in the photosphere. The resolving power of 4-m-class telescopes, such as the DKIST, is needed for an unambiguous detection of them. The movie associated to Fig. 1 is available at http://www.aanda.org

  10. Observation of Magnetic Reconnection at a 3D Null Point Associated with a Solar Eruption

    NASA Astrophysics Data System (ADS)

    Sun, J. Q.; Zhang, J.; Yang, K.; Cheng, X.; Ding, M. D.

    2016-10-01

    Magnetic null has long been recognized as a special structure serving as a preferential site for magnetic reconnection (MR). However, the direct observational study of MR at null-points is largely lacking. Here, we show the observations of MR around a magnetic null associated with an eruption that resulted in an M1.7 flare and a coronal mass ejection. The Geostationary Operational Environmental Satellites X-ray profile of the flare exhibited two peaks at ∼02:23 UT and ∼02:40 UT on 2012 November 8, respectively. Based on the imaging observations, we find that the first and also primary X-ray peak was originated from MR in the current sheet (CS) underneath the erupting magnetic flux rope (MFR). On the other hand, the second and also weaker X-ray peak was caused by MR around a null point located above the pre-eruption MFR. The interaction of the null point and the erupting MFR can be described as a two-step process. During the first step, the erupting and fast expanding MFR passed through the null point, resulting in a significant displacement of the magnetic field surrounding the null. During the second step, the displaced magnetic field started to move back, resulting in a converging inflow and subsequently the MR around the null. The null-point reconnection is a different process from the current sheet reconnection in this flare; the latter is the cause of the main peak of the flare, while the former is the cause of the secondary peak of the flare and the conspicuous high-lying cusp structure.

  11. Magnetic elliptical polarization of Schumann resonances

    NASA Technical Reports Server (NTRS)

    Sentman, D. D.

    1987-01-01

    Measurements of orthogonal, horizontal components of the magnetic field in the ELF range obtained during September 1985 show that the Schumann resonance eigenfrequencies determined separately for the north-south and east-west magnetic components differ by as much as 0.5 Hz, suggesting that the underlying magnetic signal is not linearly polarized at such times. The high degree of magnetic ellipticity found suggests that the side multiplets of the Schumann resonances corresponding to azimuthally inhomogeneous normal modes are strongly excited in the highly asymmetric earth-ionosphere cavity. The dominant sense of polarization over the measurement passband is found to be right-handed during local daylight hours, and to be left-handed during local nighttime hours.

  12. Magnetic resonance microscopy in biomedical research.

    PubMed

    Serša, I

    2012-01-01

    Magnetic resonance (MR) microscopy is a special modality of MRI with an emphasis on high spatial resolution. While its main principle is identical to conventional clinical MRI, there are several differences between the two that are mainly associated with a use of stronger magnets and gradients. MR microscopy has numerous interesting applications in material and bio sciences in which high spatial resolution is demanded and long experiment times are allowed.

  13. Resonant magnetic scattering of polarized soft x rays

    SciTech Connect

    Sacchi, M.; Hague, C.F.; Gullikson, E.M.; Underwood, J.

    1997-04-01

    Magnetic effects on X-ray scattering (Bragg diffraction, specular reflectivity or diffuse scattering) are a well known phenomenon, and they also represent a powerful tool for investigating magnetic materials since it was shown that they are strongly enhanced when the photon energy is tuned across an absorption edge (resonant process). The resonant enhancement of the magnetic scattering has mainly been investigated at high photon energies, in order to match the Bragg law for the typical lattice spacings of crystals. In the soft X-ray range, even larger effects are expected, working for instance at the 2p edges of transition metals of the first row or at the 3d edges of rare earths (300-1500 eV), but the corresponding long wavelengths prevent the use of single crystals. Two approaches have been recently adopted in this energy range: (i) the study of the Bragg diffraction from artificial structures of appropriate 2d spacing; (ii) the analysis of the specular reflectivity, which contains analogous information but has no constraints related to the lattice spacing. Both approaches have their own specific advantages: for instance, working under Bragg conditions provides information about the (magnetic) periodicity in ordered structures, while resonant reflectivity can easily be related to electronic properties and absorption spectra. An important aspect common to all the resonant X-ray scattering techniques is the element selectivity inherent to the fact of working at a specific absorption edge: under these conditions, X-ray scattering becomes in fact a spectroscopy. Results are presented for films of iron and cobalt.

  14. A 3D model of crustal magnetization at the Pinacate Volcanic Field, NW Sonora, Mexico

    NASA Astrophysics Data System (ADS)

    García-Abdeslem, Juan; Calmus, Thierry

    2015-08-01

    The Pinacate Volcanic Field (PVF) is located near the western border of the southern Basin and Range province, in the State of Sonora NW Mexico, and within the Gulf of California Extensional Province. This volcanic field contains the shield volcano Santa Clara, which mainly consists of basaltic to trachytic volcanic rocks, and reaches an altitude of 1200 m. The PVF disrupts a series of discontinuous ranges of low topographic relief aligned in a NW direction, which consist mainly of Proterozoic metamorphic rocks and Proterozoic through Paleogene granitoids. The PVF covers an area of approximately 60 by 55 km, and includes more than 400 well-preserved cinder cones and vents and eight maar craters. It was active from about 1.7 Ma until about 13 ka. We have used the ages and magnetic polarities of the volcanic rocks, along with mapped magnetic anomalies and their inverse modeling to determine that the Pinacate Volcanic Field was formed during two volcanic episodes. The oldest one built the Santa Clara shield volcano of basaltic and trachytic composition, and occurred during the geomagnetic Matuyama Chron of reverse polarity, which also includes the normal polarity Jaramillo and Olduvai Subchrons, thus imprinting both normal and reverse magnetization in the volcanic products. The younger Pinacate series of basaltic composition represents monogenetic volcanic activity that extends all around the PVF and occurred during the subsequent geomagnetic Brunhes Chron of normal polarity. Magnetic anomalies toward the north of the Santa Clara volcano are the most intense in the PVF, and their inverse modeling indicates the presence of a large subsurface body magnetized in the present direction of the geomagnetic field. This suggests that the magma chambers at depth cooled below the Curie temperature during the Brunhes Chron.

  15. Enhancement of artificial magnetism via resonant bianisotropy

    PubMed Central

    Markovich, Dmitry; Baryshnikova, Kseniia; Shalin, Alexander; Samusev, Anton; Krasnok, Alexander; Belov, Pavel; Ginzburg, Pavel

    2016-01-01

    All-dielectric “magnetic light” nanophotonics based on high refractive index nanoparticles allows controlling magnetic component of light at nanoscale without having high dissipative losses. The artificial magnetic optical response of such nanoparticles originates from circular displacement currents excited inside those structures and strongly depends on geometry and dispersion of optical materials. Here an approach for enhancing of magnetic response via resonant bianisotropy effect is proposed and analyzed. The key mechanism of enhancement is based on electric-magnetic interaction between two electrically and magnetically resonant nanoparticles of all-dielectric dimer. It was shown that proper geometrical arrangement of the dimer in respect to the incident illumination direction allows flexible control over all vectorial components of the magnetic moment, tailoring the latter in the dynamical range of 100% and delivering enhancement up to 36% relative to performances of standalone spherical particles. The proposed approach provides pathways for designs of all-dielectric metamaterials and metasurfaces with strong magnetic responses. PMID:26941126

  16. Reconstruction of 3D Coronal Magnetic Structures from THEMIS/MTR and Hinode/SOT Vector Maps

    NASA Astrophysics Data System (ADS)

    Schmieder, B.; Guo, Y.; Aulanier, G.; Démoulin, P.; Török, T.; Bommier, V.; Wiegelmann, T.; Gosain, S.

    2012-08-01

    Coordinated campaigns using THEMIS, Hinode, and other instruments have allowed us to study the magnetic fields of faculae, filaments, and active regions. In a first case, we modelled the 3D magnetic field in a flaring active region with a nonlinear force-free field extrapolation, using magnetic vectors observed by THEMIS/MTR as boundary condition. In order to construct a consistent bottom boundary for the model, we first removed the 180 degree ambiguity of the transverse fields and minimized the force and torque in the observed vector fields. We found a twisted magnetic flux rope, well aligned with the polarity inversion line and a part of an Hα filament, and located where a large flare is initiated about two hours later. In a second case, Hinode/SOT allowed us to detect fine flux concentrations in faculae, while MTR provided us with magnetic information at different levels in the atmosphere. The polarimetry analysis of the MTR and SOT data gave consistent results, using both UNNOFIT and MELANIE inversion codes.

  17. 3D modeling inversion calculation of magnetic data using iterative reweighted least squares at the Lau basin, Southwest Pacific

    NASA Astrophysics Data System (ADS)

    Choi, S.; Kim, C.; Kim, H. R.; Park, C.; Park, H. Y.

    2015-12-01

    We performed the marine magnetic and the bathymetry survey in the Lau basin for finding the submarine hydrothermal deposits in October 2009. We acquired magnetic and bathymetry datasets by using Overhouser Proton Magnetometer SeaSPY(Marine Magnetics Co.) and Multi-Beam Echo Sounder EM120(Kongsberg Co.). We conducted the data processing to obtain detailed seabed topography, magnetic anomaly and reduction to the pole(RTP). The Lau basin is one of the youngest back-arc basins in the Southwest Pacific. This region was a lot of hydrothermal activities and hydrothermal deposits. In particular, Tofua Arc(TA) in the Lau basin consists of various and complex stratovolcanos(from Massoth et al., 2007).), We calculated the magnetic susceptibility distribution of the TA19-1 seamount(longitude:176°23.5'W, latitude: 22°42.5'W)area using the RTP data by 3-D magnetic inversion from Jung's previous study(2013). Based on 2D 'compact gravity inversion' by Last & Kubik(1983), we expend it to the 3D algorithm using iterative reweighted least squares method with some weight matrices. The used weight matrices are two types: 1) the minimum gradient support(MGS) that controls the spatial distribution of the solution from Porniaguine and Zhdanov(1999); 2) the depth weight that are used according to the shape of subsurface structures. From the modeling, we derived the appropriate scale factor for the use of depth weight and setting magnetic susceptibility. Furthermore, we have to enter a very small error value to control the computation of the singular point of the inversion model that was able to be easily calculated for modeling. In addition, we applied separately weighted value for the correct shape and depth of the magnetic source. We selected the best results model by change to converge of RMS. Compared between the final modeled result and RTP values in this study, they are generally similar to the each other. But the input values and the modeled values have slightly little difference

  18. Sensitivity of a 3D fully-gapped topological superconductor to non-magnetic impurities

    NASA Astrophysics Data System (ADS)

    Ota, Yukihiro; Nagai, Yuki; Machida, Masahiko

    2015-03-01

    Topological superconductors (TSC) are notable materials, owing to the mathematical curiosity and the application potential. The bulk TSC can emerge by copper intercalation into topological insulator Bi2Se3. In this paper, we theoretically study the non-magnetic impurity effects in the mean-field model of CuxBi2Se3, focusing on the odd-parity fully-gapped superconducting state. Calculating the density of states with a self-consistent T-matrix approach, we test the presence of mid-gap states, leading to pair-breaking effects. Remarkably, the sensitivity to non-magnetic impurities strongly depend on a normal-state dispersion character, i.e., either non-relativistic or relativistic dispersion relations. We show unification picture for understanding this intriguing result, deriving a low-energy effective superconducting theory.

  19. Simulations of Gyrosynchrotron Microwave Emission from an Oscillating 3D Magnetic Loop

    NASA Astrophysics Data System (ADS)

    Kuznetsov, A. A.; Van Doorsselaere, T.; Reznikova, V. E.

    2015-04-01

    Radio observations of solar flares often reveal various periodic or quasi-periodic oscillations. Most likely, these oscillations are caused by magnetohydrodynamic (MHD) oscillations of flaring loops which modulate the emission. Interpreting the observations requires comparing them with simulations. We simulated the gyrosynchrotron radio emission from a semicircular (toroidal-shaped) magnetic loop containing sausage-mode MHD oscillations. The aim was to detect the observable signatures specific to the considered MHD mode and to study their dependence on the various source parameters. The MHD waves were simulated using a linear three-dimensional model of a magnetized plasma cylinder; both standing and propagating waves were considered. The curved loop was formed by replicating the MHD solutions along the plasma cylinder and bending the cylinder; this model allowed us to study the effect of varying the viewing angle along the loop. The radio emission was simulated using a three-dimensional model, and its spatial and temporal variations were analyzed. We considered several loop orientations and different parameters of the magnetic field, plasma, and energetic electrons in the loop. In the model with low plasma density, the intensity oscillations at all frequencies are synchronous (with the exception of a narrow spectral region below the spectral peak). In the model with high plasma density, the emission at low frequencies (where the Razin effect is important) oscillates in anti-phase with the emissions at higher frequencies. The oscillations at high and low frequencies are more pronounced in different parts of the loop (depending on the loop orientation). The layers where the line-of-sight component of the magnetic field changes sign can produce additional peculiarities in the oscillation patterns.

  20. Adsorbent 2D and 3D carbon matrices with protected magnetic iron nanoparticles.

    PubMed

    Carreño, N L V; Escote, M T; Valentini, A; McCafferty, L; Stolojan, V; Beliatis, M; Mills, C A; Rhodes, R; Smith, C T G; Silva, S R P

    2015-11-07

    We report on the synthesis of two and three dimensional carbonaceous sponges produced directly from graphene oxide (GO) into which functionalized iron nanoparticles can be introduced to render it magnetic. This simple, low cost procedure, wherein an iron polymeric resin precursor is introduced into the carbon framework, results in carbon-based materials with specific surface areas of the order of 93 and 66 m(2) g(-1), compared to approx. 4 m(2) g(-1) for graphite, decorated with ferromagnetic iron nanoparticles giving coercivity fields postulated to be 216 and 98 Oe, values typical for ferrite magnets, for 3.2 and 13.5 wt% Fe respectively. The strongly magnetic iron nanoparticles are robustly anchored to the GO sheets by a layer of residual graphite, on the order of 5 nm, formed during the pyrolysis of the precursor material. The applicability of the carbon sponges is demonstrated in their ability to absorb, store and subsequently elute an organic dye, Rhodamine B, from water as required. It is possible to regenerate the carbon-iron hybrid material after adsorption by eluting the dye with a solvent to which it has a high affinity, such as ethanol. The use of a carbon framework opens the hybrid materials to further chemical functionalization, for enhanced chemical uptake of contaminants, or co-decoration with, for example, silver nanoparticles for bactericidal properties. Such analytical properties, combined with the material's magnetic character, offer solutions for environmental decontamination at land and sea, wastewater purification, solvent extraction, and for the concentration of dilute species.

  1. Adsorbent 2D and 3D carbon matrices with protected magnetic iron nanoparticles

    NASA Astrophysics Data System (ADS)

    Carreño, N. L. V.; Escote, M. T.; Valentini, A.; McCafferty, L.; Stolojan, V.; Beliatis, M.; Mills, C. A.; Rhodes, R.; Smith, C. T. G.; Silva, S. R. P.

    2015-10-01

    We report on the synthesis of two and three dimensional carbonaceous sponges produced directly from graphene oxide (GO) into which functionalized iron nanoparticles can be introduced to render it magnetic. This simple, low cost procedure, wherein an iron polymeric resin precursor is introduced into the carbon framework, results in carbon-based materials with specific surface areas of the order of 93 and 66 m2 g-1, compared to approx. 4 m2 g-1 for graphite, decorated with ferromagnetic iron nanoparticles giving coercivity fields postulated to be 216 and 98 Oe, values typical for ferrite magnets, for 3.2 and 13.5 wt% Fe respectively. The strongly magnetic iron nanoparticles are robustly anchored to the GO sheets by a layer of residual graphite, on the order of 5 nm, formed during the pyrolysis of the precursor material. The applicability of the carbon sponges is demonstrated in their ability to absorb, store and subsequently elute an organic dye, Rhodamine B, from water as required. It is possible to regenerate the carbon-iron hybrid material after adsorption by eluting the dye with a solvent to which it has a high affinity, such as ethanol. The use of a carbon framework opens the hybrid materials to further chemical functionalization, for enhanced chemical uptake of contaminants, or co-decoration with, for example, silver nanoparticles for bactericidal properties. Such analytical properties, combined with the material's magnetic character, offer solutions for environmental decontamination at land and sea, wastewater purification, solvent extraction, and for the concentration of dilute species.

  2. Orbital driven impurity spin effect on the magnetic order of quasi-3D cupric oxide

    NASA Astrophysics Data System (ADS)

    Ganga, B. G.; Santhosh, P. N.; Nanda, B. R. K.

    2017-04-01

    Density functional calculations are performed to study the magnetic order of the severely distorted square planar cupric oxide (CuO) and local spin disorder in it in the presence of the transition metal impurities M (=Cr, Mn, Fe, Co and Ni). The distortion in the crystal structure, arisen to reduce the band energy by minimizing the covalent interaction, creates two crisscrossing zigzag spin-1/2 chains. From the spin dimer analysis we find that while the spin chain along ≤ft[1 0 \\bar{1}\\right] has strong Heisenberg type antiferromagnetic coupling (J ~ 127 meV), along ≤ft[1 0 1\\right] it exhibits weak, but robust, ferromagnetic coupling (J ~ 9 meV) mediated by reminiscent p-d covalent interactions. The impurity effect on the magnetic ordering is independent of M and purely orbital driven. If the given spin-state of M is such that the {{d}{{x2}-{{y}2}}} orbital is spin-polarized, then the original long-range ordering is maintained. However, if {{d}{{x2}-{{y}2}}} orbital is unoccupied, the absence of corresponding covalent interaction breaks the weak ferromagnetic coupling and a spin-flip takes place at the impurity site leading to breakdown of the long range magnetic ordering.

  3. 3-D Modelling of Magnetic Data from an Archaeological Site in Northwestern Tlaxcala State, Mexico

    NASA Astrophysics Data System (ADS)

    Chavez, R. E.; Argote, D. L.; Cifuentes, G.; Tejero, A.; Camara, E.

    2009-05-01

    In Archaeology, geophysical methods had been applied usually in a qualitative form, limited only to the use of filters that enhance the data display. The main objective in this work is the implementation of a modeling technique that allows us to reconstruct the geometry of buried bodies and the determination of their depths. This is done by means of the estimation of the magnetic moments of archaeological objects using a three- dimensional mesh of individual magnetic dipoles using the least squares method and the singular value decomposition of a weighted matrix to solve the linear problem. The distribution and shape of the underlying archaeological remains can be inferred. This methodology was applied to an archaeological site called Los Teteles de Ocotitla, in the state of Tlaxcala, Mexico. A high-resolution magnetic prospection was carried out in three selected areas (terraces). The most important total field anomalies found on each area were inverted, obtaining results that were corroborated by archaeological excavations. This investigation demonstrates the potential of quantitative geophysical methods for the characterization of archaeological structures, in extension and in depth.

  4. Orbital driven impurity spin effect on the magnetic order of quasi-3D cupric oxide.

    PubMed

    Ganga, B G; Santhosh, P N; Nanda, B R K

    2017-04-20

    Density functional calculations are performed to study the magnetic order of the severely distorted square planar cupric oxide (CuO) and local spin disorder in it in the presence of the transition metal impurities M (=Cr, Mn, Fe, Co and Ni). The distortion in the crystal structure, arisen to reduce the band energy by minimizing the covalent interaction, creates two crisscrossing zigzag spin-1/2 chains. From the spin dimer analysis we find that while the spin chain along [Formula: see text] has strong Heisenberg type antiferromagnetic coupling (J ~ 127 meV), along [Formula: see text] it exhibits weak, but robust, ferromagnetic coupling (J ~ 9 meV) mediated by reminiscent p-d covalent interactions. The impurity effect on the magnetic ordering is independent of M and purely orbital driven. If the given spin-state of M is such that the [Formula: see text] orbital is spin-polarized, then the original long-range ordering is maintained. However, if [Formula: see text] orbital is unoccupied, the absence of corresponding covalent interaction breaks the weak ferromagnetic coupling and a spin-flip takes place at the impurity site leading to breakdown of the long range magnetic ordering.

  5. The Effect of Dissipation Mechanism on X-line Spreading in 3D Magnetic

    NASA Astrophysics Data System (ADS)

    Shepherd, L. S.; Cassak, P.; Phan, T.; Shay, M. A.; Gosling, J. T.

    2012-12-01

    Naturally occurring magnetic reconnection generally begins in a spatially localized region and spreads in the direction perpendicular to the reconnection plane as time progresses. Reconnection spreading is associated with dawn-dusk asymmetries during substorms in the magnetotail and has been observed in two-ribbon flares (such as the Bastille Day flare) and laboratory experiments at the Versatile Toroidal Facility (VTF) and the Magnetic Reconnection eXperiment (MRX). It was suggested that X-line spreading is necessary to explain the existence of X-lines extending more than 390 Earth radii (Phan et al., Nature, 404, 848, 2006). Previous numerical studies exploring the spreading of localized magnetic reconnection exclusively addressed collisionless (Hall) reconnection. Here, we address the effect of dissipation mechanism has on X-line spreading with and without a guide field. We compare previous results with simulations using three alternate phases of reconnection - Sweet-Parker reconnection, collisional reconnection with secondary islands, and reconnection with anomalous resistivity. We present results from three-dimensional resistive magnetohydrodynamic numerical simulations to address the nature of X-line spreading. Applications to reconnection in the solar wind and corona will be discussed.

  6. Tunable electronic and magnetic properties in stanene by 3d transition metal atoms absorption

    NASA Astrophysics Data System (ADS)

    Xing, Dan-Xu; Ren, Ceng-Ceng; Zhang, Shu-Feng; Feng, Yong; Chen, Xin-Lian; Zhang, Chang-Wen; Wang, Pei-Ji

    2017-03-01

    The electronic and magnetic properties of transition metal (TM) atoms (V, Cr, Mn, Fe, Co, Ni) adsorption on stanene are investigated by first-principles calculations. The results indicate that the TM atoms prefer to be relaxed on a H site on stanene except V atom which lies on the valley site. Fe-absorbed stanene is a spin gapless semiconductor with up-spin electron and down-spin hole carriers allowing the coexistence of charge current and the pure spin current. Co-absorbed stanene lies in the half metal phase. The V-, Cr-, Mn-, and Cu-absorbed stanene turn the stanene into metal, while Ni- and Zn-absorbed stanene open a narrow band gap. For V-, Cr-, Mn-, Fe-, and Co-absorbed stanene, the magnetic moment of the TM will survive while the Ni-, Cu-, and Zn-absorbed stanene will be non-magnetic material. These findings may have great potential in the design of new electrically controllable spintronic devices.

  7. 3-D RPIC simulations of relativistic jets: Particle acceleration, magnetic field generation, and emission

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.

    2006-01-01

    Nonthermal radiation observed from astrophysical systems containing (relativistic) jets and shocks, e.g., supernova remnants, active galactic nuclei (AGNs), gamma-ray bursts (GRBs), and Galactic microquasar systems usually have power-law emission spectra. Fermi acceleration is the mechanism usually assumed for the acceleration of particles in astrophysical environments. Recent PIC simulations using injected relativistic electron-ion (electro-positron) jets show that acceleration occurs within the downstream jet, rather than by the scattering of particles back and forth across the shock as in Fermi acceleration. Shock acceleration is a ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, other two-streaming instability, and the Weibel instability) created in the .shocks are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The "jitter" radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants. We will review recent PIC simulations which show particle acceleration in jets.

  8. Imaging Intelligence with Proton Magnetic Resonance Spectroscopy

    ERIC Educational Resources Information Center

    Jung, Rex E.; Gasparovic, Charles; Chavez, Robert S.; Caprihan, Arvind; Barrow, Ranee; Yeo, Ronald A.

    2009-01-01

    Proton magnetic resonance spectroscopy ([to the first power]H-MRS) is a technique for the assay of brain neurochemistry "in vivo." N-acetylaspartate (NAA), the most prominent metabolite visible within the [to the first power]H-MRS spectrum, is found primarily within neurons. The current study was designed to further elucidate NAA-cognition…

  9. Giant infantile gliosarcoma: magnetic resonance imaging findings.

    PubMed

    Sanal, Hatice Tuba; Bulakbasi, Nail; Kocaoglu, Murat; Onguru, Onder; Chen, Lina

    2008-08-01

    Gliosarcoma is an uncommon variant of glioblastoma multiforme, which is composed of gliomatous and sarcomatous elements. The tumor is rarely encountered in childhood. This case report presents the magnetic resonance imaging characteristics of a giant gliosarcoma in a 3-year-old girl. Size and location of the tumor are described.

  10. Sample spinner for nuclear magnetic resonance spectrometer

    SciTech Connect

    Stejskal, E.O.

    1984-05-01

    A sample spinner for a nuclear magnetic resonance spectrometer having improved operating characteristics is described comprising a rotor supported at both ends by support gas bearings and positioned by a thrust gas bearing. Improved support gas bearings are also described which result in a spinner exhibiting long-term stable operation characteristics.

  11. An improved nuclear magnetic resonance spectrometer

    NASA Technical Reports Server (NTRS)

    Elleman, D. D.; Manatt, S. L.

    1967-01-01

    Cylindrical sample container provides a high degree of nuclear stabilization to a nuclear magnetic resonance /nmr/ spectrometer. It is placed coaxially about the nmr insert and contains reference sample that gives a signal suitable for locking the field and frequency of an nmr spectrometer with a simple audio modulation system.

  12. Nuclear Magnetic Resonance Technology for Medical Studies.

    ERIC Educational Resources Information Center

    Budinger, Thomas F.; Lauterbur, Paul C.

    1984-01-01

    Reports on the status of nuclear magnetic resonance (NMR) from theoretical and clinical perspectives, reviewing NMR theory and relaxation parameters relevant to NMR imaging. Also reviews literature related to modern imaging strategies, signal-to-noise ratio, contrast agents, in vivo spectroscopy, spectroscopic imaging, clinical applications, and…

  13. Pituitary magnetic resonance imaging in Cushing's disease.

    PubMed

    Vitale, Giovanni; Tortora, Fabio; Baldelli, Roberto; Cocchiara, Francesco; Paragliola, Rosa Maria; Sbardella, Emilia; Simeoli, Chiara; Caranci, Ferdinando; Pivonello, Rosario; Colao, Annamaria

    2017-03-01

    Adrenocorticotropin-secreting pituitary tumor represents about 10 % of pituitary adenomas and at the time of diagnosis most of them are microadenomas. Transsphenoidal surgery is the first-line treatment of Cushing's disease and accurate localization of the tumor within the gland is essential for selectively removing the lesion and preserving normal pituitary function. Magnetic resonance imaging is the best imaging modality for the detection of pituitary tumors, but adrenocorticotropin-secreting pituitary microadenomas are not correctly identified in 30-50 % of cases, because of their size, location, and enhancing characteristics. Several recent studies were performed with the purpose of better localizing the adrenocorticotropin-secreting microadenomas through the use in magnetic resonance imaging of specific sequences, reduced contrast medium dose and high-field technology. Therefore, an improved imaging technique for pituitary disease is mandatory in the suspect of Cushing's disease. The aims of this paper are to present an overview of pituitary magnetic resonance imaging in the diagnosis of Cushing's disease and to provide a magnetic resonance imaging protocol to be followed in case of suspicion adrenocorticotropin-secreting pituitary adenoma.

  14. Brain Morphometry Using Anatomical Magnetic Resonance Imaging

    ERIC Educational Resources Information Center

    Bansal, Ravi; Gerber, Andrew J.; Peterson, Bradley S.

    2008-01-01

    The efficacy of anatomical magnetic resonance imaging (MRI) in studying the morphological features of various regions of the brain is described, also providing the steps used in the processing and studying of the images. The ability to correlate these features with several clinical and psychological measures can help in using anatomical MRI to…

  15. Magnetic Resonance Imaging in Biomedical Engineering

    NASA Astrophysics Data System (ADS)

    Kaśpar, Jan; Hána, Karel; Smrčka, Pavel; Brada, Jiří; Beneš, Jiří; Šunka, Pavel

    2007-11-01

    The basic principles of magnetic resonance imaging covering physical principles and basic imaging techniques will be presented as a strong tool in biomedical engineering. Several applications of MRI in biomedical research practiced at the MRI laboratory of the FBMI CTU including other laboratory instruments and activities are introduced.

  16. Optimal magnetic resonance imaging of the brain.

    PubMed

    Robertson, Ian

    2011-01-01

    Quality magnetic resonance (MR) imaging is complex and requires optimization of many technical factors. The most important factors are: magnet field and gradient strengths, coil selection, receiver bandwidth, field of view and image matrix size, number of excitations, slice thickness, image weighting and contrast, imaging planes and the direction of the phase, and frequency gradients. The ability to augment a standard MR study with additional sequences, and the need to ensure the completed study is comprehensive and robust must be balanced against the time the patient spends under anesthesia in the magnet.

  17. Magnetic resonance investigation of magnetic-labeled baker's yeast cells

    NASA Astrophysics Data System (ADS)

    Godoy Morais, J. P. M.; Azevedo, R. B.; Silva, L. P.; Lacava, Z. G. M.; Báo, S. N.; Silva, O.; Pelegrini, F.; Gansau, C.; Buske, N.; Safarik, I.; Safarikova, M.; Morais, P. C.

    2004-05-01

    In this study, the interaction of DMSA-coated magnetite nanoparticles (5 and 10 nm core-size) with Saccharomyces cerevisae was investigated using magnetic resonance (MR) and transmission electron microscopy (TEM). The TEM micrographs revealed magnetite nanoparticles attached externally to the cell wall. The MR data support the strong interaction among the nanoparticles supported by the cells. A remarkable shift in the resonance field was used as signature of particle attachment to the cell wall.

  18. Self-assembly of a 3d-5f trinuclear single-molecule magnet from a pentavalent uranyl complex.

    PubMed

    Chatelain, Lucile; Walsh, James P S; Pécaut, Jacques; Tuna, Floriana; Mazzanti, Marinella

    2014-12-01

    Mixed-metal uranium compounds are very attractive candidates in the design of single-molecule magnets (SMMs), but only one 3d-5f hetero-polymetallic SMM containing a uranium center is known. Herein, we report two trimeric heterodimetallic 3d-5f complexes self-assembled by cation-cation interactions between a uranyl(V) complex and a TPA-capped M(II)  complex (M=Mn (1), Cd (2); TPA=tris(2-pyridylmethyl)amine). The metal centers were strategically chosen to promote the formation of discrete molecules rather than extended chains. Compound 1, which contains an almost linear {MnOUOMn} core, exhibits SMM behavior with a relaxation barrier of 81±0.5 K-the highest reported for a mono-uranium system-arising from intramolecular Mn-U exchange interactions combined with the high Ising anisotropy of the uranyl(V) moiety. Compound 1 also exhibits an open magnetic hysteresis loop at temperatures less than 3 K, with a significant coercive field of 1.9 T at 1.8 K.

  19. Semantic image retrieval in magnetic resonance brain volumes.

    PubMed

    Quddus, Azhar; Basir, Otman

    2012-05-01

    Practitioners in the area of neurology often need to retrieve multimodal magnetic resonance (MR) images of the brain to study disease progression and to correlate observations across multiple subjects. In this paper, a novel technique for retrieving 2-D MR images (slices) in 3-D brain volumes is proposed. Given a 2-D MR query slice, the technique identifies the 3-D volume among multiple subjects in the database, associates the query slice with a specific region of the brain, and retrieves the matching slice within this region in the identified volumes. The proposed technique is capable of retrieving an image in multimodal and noisy scenarios. In this study, support vector machines (SVM) are used for identifying 3-D MR volume and for performing semantic classification of the human brain into various semantic regions. In order to achieve reliable image retrieval performance in the presence of misalignments, an image registration-based retrieval framework is developed. The proposed retrieval technique is tested on various modalities. The test results reveal superior robustness performance with respect to accuracy, speed, and multimodality.

  20. Spine labeling in axial magnetic resonance imaging via integral kernels.

    PubMed

    Miles, Brandon; Ben Ayed, Ismail; Hojjat, Seyed-Parsa; Wang, Michael H; Li, Shuo; Fenster, Aaron; Garvin, Gregory J

    2016-12-01

    This study investigates a fast integral-kernel algorithm for classifying (labeling) the vertebra and disc structures in axial magnetic resonance images (MRI). The method is based on a hierarchy of feature levels, where pixel classifications via non-linear probability product kernels (PPKs) are followed by classifications of 2D slices, individual 3D structures and groups of 3D structures. The algorithm further embeds geometric priors based on anatomical measurements of the spine. Our classifier requires evaluations of computationally expensive integrals at each pixel, and direct evaluations of such integrals would be prohibitively time consuming. We propose an efficient computation of kernel density estimates and PPK evaluations for large images and arbitrary local window sizes via integral kernels. Our method requires a single user click for a whole 3D MRI volume, runs nearly in real-time, and does not require an intensive external training. Comprehensive evaluations over T1-weighted axial lumbar spine data sets from 32 patients demonstrate a competitive structure classification accuracy of 99%, along with a 2D slice classification accuracy of 88%. To the best of our knowledge, such a structure classification accuracy has not been reached by the existing spine labeling algorithms. Furthermore, we believe our work is the first to use integral kernels in the context of medical images.

  1. Nuclear Magnetic Resonance Imaging. South Carolina Health Service Area 2

    SciTech Connect

    Not Available

    1984-12-01

    Contents include: Nuclear Magnetic Resonance Imaging (NMRI); (Clinical applications, Magnet types, Comparisons with other systems, Manpower, Manufacturers, Contraindications); Analysis of systems; (Availability, Accessibility, Cost, Quality, Continuity, Acceptability).

  2. Magnetic Resonance Force Microscopy Detected Long-Lived Spin Magnetization.

    PubMed

    Chen, Lei; Longenecker, Jonilyn G; Moore, Eric W; Marohn, John A

    2013-07-01

    Magnetic resonance force microscopy (MRFM), which combines magnetic resonance imaging with scanning probe microscopy together, is capable of performing ultra-sensitive detection of spin magnetization. In an attempt to observe dynamic nuclear polarization (DNP) in an MRFM experiment, which could possibly further improve its sensitivity towards a single proton spin, a film of perdeuterated polystyrene doped with a nitroxide electron-spin probe was prepared. A high-compliance cantilever with a 4 μm diameter magnetic tip was brought near the film at a temperature of 7.3 K and in a background magnetic field of ~0.6 T. The film was irradiated with 16.7 GHz microwaves while the resulting transient change in cantilever frequency was recorded in real time. In addition to observing the expected prompt change in cantilever frequency due to saturation of the nitroxide's electron-spin magnetization, we observed a persistent cantilever frequency change. Based on its magnitude, lifetime, and field dependence, we tentatively attribute the persistent signal to polarized deuteron magnetization created via transfer of magnetization from electron spins. Further measurements of the persistent signal's dependence on the cantilever amplitude and tip-sample separation are presented and explained by the cross-effect DNP mechanism in high magnetic field gradients.

  3. Interaction of magnetic resonators studied by the magnetic field enhancement

    SciTech Connect

    Hou, Yumin

    2013-12-15

    It is the first time that the magnetic field enhancement (MFE) is used to study the interaction of magnetic resonators (MRs), which is more sensitive than previous parameters–shift and damping of resonance frequency. To avoid the coherence of lattice and the effect of Bloch wave, the interaction is simulated between two MRs with same primary phase when the distance is changed in the range of several resonance wavelengths, which is also compared with periodic structure. The calculated MFE oscillating and decaying with distance with the period equal to resonance wavelength directly shows the retardation effect. Simulation also shows that the interaction at normal incidence is sensitive to the phase correlation which is related with retardation effect and is ultra-long-distance interaction when the two MRs are strongly localized. When the distance is very short, the amplitude of magnetic resonance is oppressed by the strong interaction and thus the MFE can be much lower than that of single MR. This study provides the design rules of metamaterials for engineering resonant properties of MRs.

  4. Magnetic resonance imaging in inflammatory rheumatoid diseases.

    PubMed

    Sudoł-Szopińska, Iwona; Mróz, Joanna; Ostrowska, Monika; Kwiatkowska, Brygida

    2016-01-01

    Magnetic resonance (MR) is used more and more frequently to diagnose changes in the musculoskeletal system in the course of rheumatic diseases, at their initial assessment, for treatment monitoring and for identification of complications. The article presents the history of magnetic resonance imaging, the basic principles underlying its operation as well as types of magnets, coils and MRI protocols used in the diagnostic process of rheumatic diseases. It enumerates advantages and disadvantages of individual MRI scanners. The principles of MRI coil operation are explained, and the sequences used for MR image analysis are described, particularly in terms of their application in rheumatology, including T1-, T2-, PD-weighted, STIR/TIRM and contrast-enhanced T1-weighted images. Furthermore, views on the need to use contrast agents to optimise diagnosis, particularly in synovitis-like changes, are presented. Finally, methods for the assessment of MR images are listed, including the semi-quantitative method by RAMRIS and quantitative dynamic examination.

  5. Nuclear magnetic resonance properties of lunar samples.

    NASA Technical Reports Server (NTRS)

    Kline, D.; Weeks, R. A.

    1972-01-01

    Nuclear magnetic resonance spectra of Na-23, Al-27, and P-31 in fines samples 10084,60 and 14163,168 and in crystalline rock samples 12021,55 and 14321,166, have been recorded over a range of frequencies up to 20 MHz. A shift in the field at which maximum absorption occurs for all of the spectra relative to the field at which maximum absorption occurs for terrestrial analogues is attributed to a sample-dependent magnetic field at the Na, Al, and P sites opposing the laboratory field. The magnitude of these fields internal to the samples is sample dependent and varies from 5 to 10 G. These fields do not correlate with the iron content of the samples. However, the presence of single-domain particles of iron distributed throughout the plagioclase fraction that contains the principal fraction of Na and Al is inferred from electron magnetic resonance spectra shapes.

  6. Magnetic Earth Ionosphere Resonant Frequencies

    NASA Technical Reports Server (NTRS)

    Spaniol, Craig

    1994-01-01

    The Community College Division is pleased to report progress of NASA funded research at West Virginia State College. During this reporting period, the project research group has continued with activities to develop instrumentation capability designed to monitor resonant cavity frequencies in the atmospheric region between the Earth's surface and the ionosphere. In addition, the project's principal investigator, Dr. Craig Spaniol, and NASA technical officer, Dr. John Sutton, have written and published technical papers intended to expand the scientific and technical framework needed for project research. This research continues to provide an excellent example of government and education working together to provide significant research in the college environment. This cooperative effort has provided many students with technical project work which compliments their education.

  7. 3-D Modelling of Stretched Solitary Waves along Magnetic Field Lines

    NASA Astrophysics Data System (ADS)

    Muschietti, L.; Roth, I.; Carlson, C. W.; Berthomier, M.

    2001-12-01

    A model is presented for a new type of fast solitary waves which is observed by FAST in downward current regions of the auroral zone. The three-dimensional, coherent structures are electrostatic, have a positive potential, and move along the ambient magnetic field lines with speeds on the order of the electron drift. Their potential profile in the parallel direction, which can be directly measured, is flat-top whereby it cannot fit to the Gaussian shape used in previous work. Their potential profile in the perpendicular direction can only be inferred from a measured unipolar electric signal. We develop an extended BGK model which includes a flattened potential and an assumed cylindrical symmetry around a centric magnetic field line. The model envisions concentric shells of trapped electrons slowly drifting azimuthally while bouncing back and forth in the parallel direction. The electron dynamics is analysed in terms of three basic motions that occur on different time scales. These are defined by the cyclotron frequency Ω e, the bounce frequency ω b, and the azimuthal drift frequency ω γ , for which explicit analytical expressions are obtained. Subject to the ordering ω γ <<ωb<< Ωe, we calculate self-consistent distribution functions in terms of approximate constants of motion. Constraints on the parameters characterizing the amplitude and shape of the stretched solitary wave are discussed.

  8. 3D Magnetically Ordered Open Supramolecular Architectures Based on Ferrimagnetic Cu/Adenine/Hydroxide Heptameric Wheels.

    PubMed

    Pérez-Aguirre, Rubén; Beobide, Garikoitz; Castillo, Oscar; de Pedro, Imanol; Luque, Antonio; Pérez-Yáñez, Sonia; Rodríguez Fernández, Jesús; Román, Pascual

    2016-08-01

    The present work provides two new examples of supramolecular metal-organic frameworks consisting of three-dimensional extended noncovalent assemblies of wheel-shaped heptanuclear [Cu7(μ-H2O)6(μ3-OH)6(μ-adeninato-κN3:κN9)6](2+) entities. The heptanuclear entity consists of a central [Cu(OH)6](4-) core connected to six additional copper(II) metal centers in a radial and planar arrangement through the hydroxides. It generates a wheel-shaped entity in which water molecules and μ-κN3:κN9 adeninato ligands bridge the peripheral copper atoms. The magnetic characterization indicates the central copper(II) center is anti-ferromagnetically coupled to external copper(II) centers, which are ferromagnetically coupled among them leading to an S = 5/2 ground state. The packing of these entities is sustained by π-π stacking interactions between the adenine nucleobases and by hydrogen bonds established among the hydroxide ligands, sulfate anions, and adenine nucleobases. The sum of both types of supramolecular interactions creates a rigid synthon that in combination with the rigidity of the heptameric entity generates an open supramolecular structure (40-50% of available space) in which additional sulfate and triethylammonium ions are located altogether with solvent molecules. These compounds represent an interesting example of materials combining both porosity and magnetic relevant features.

  9. Localization and propagation of the energy release during 3D kinetic magnetic reconnection

    NASA Astrophysics Data System (ADS)

    Lapenta, Giovanni; Markidis, Stefano; Goldman, Marty; Newman, David

    2013-04-01

    Reconnection is a key processes where energy is released: magnetic field lines break, merge in a new configuration. In the process some of the energy is released. Recent work by Shay and collaborators has pointed out that energy is released far and moving fast away from the reconnection site, at a speed exceeding several times the Alfven speed. We revisit this point, considering the release of energy from reconnection and considering both laminar processes and turbulent reconnection. We analyse the energy budget and the processes of energy transfer via Poynting flux and particle flows. The results are compared with the recent findings by Shay. The effect of the guide field can be very significant at even relatively weak strength, as our recent analysis shows. The effect on the life cycle of energy is considered. The research leading to these results has received funding from the European Commission's Seventh Framework Programme (FP7/2007-2013) under the grant agreement SWIFF (project n° 263340, www.swiff.eu). [1] M. A. Shay, J. F. Drake, J. P. Eastwood, and T. D. Phan, Super-Alfvénic Propagation of Substorm Reconnection Signatures and Poynting Flux, Phys. Rev. Lett. 107, 089901, 2011. [2] M.V. Goldman, G. Lapenta, D. L. Newman, S. Markidis, H. Che, Jet Deflection by Very Weak Guide Fields during Magnetic Reconnection, Physical Review Letters, 107, 135001, 2011.

  10. 3D calculations of the Superconducting Super Collider (SSC) 3 Tesla magnet

    SciTech Connect

    Lari, R.J.

    1984-01-01

    A 20 TeV Superconducting Super Collider (SSC) proton accelerator is being proposed by the High Energy Physics Community. One proposal would consist of a ring of magnets 164 km in circumference with a field strength of 3 Tesla and would cost 2.7 billion dollars. The magnet consists of stacked steel laminations with superconducting coils. The desired field uniformity is obtained for all fields from 0.2 to 3 Tesla by using three (or more) different pole shapes. These three different laminations are stacked in the order 1-2-3-1-2-3-... creating a truly three dimensional geometry. A three laminated stack 1-2-3 with periodic boundary conditions at 1 and 3 was assigned about 5000 finite elements per lamination and solved using the computer program TOSCA. To check the TOSCA results, the field of each of the three different shaped laminations was calculated separately using periodic boundary conditions and compared to the two dimensional field calculations using TRIM. This was done for a constant permeability of 2000 and using the B-H table for fully annealed 1010 steel. The difference of the field calculations in the region of interest was always less than +-.2%

  11. 3D imaging of magnetic particles using the 7-channel magnetoencephalography device without pre-magnetization or displacement of the sample

    NASA Astrophysics Data System (ADS)

    Polikarpov, M. A.; Ustinin, M. N.; Rykunov, S. D.; Yurenya, A. Y.; Naurzakov, S. P.; Grebenkin, A. P.; Panchenko, V. Y.

    2017-04-01

    SQUID-based magnetoencephalography device was used for the measurement of a magnetic noise generated by ferrofluid in the stationary standing vial. It was found that a free surface of the ferrofluid generates spontaneous magnetic field sufficient to detect the presence of nanoparticles in the experimental setup. The spatial distribution of elementary magnetic sources was reconstructed by the frequency-pattern analysis of multichannel time series. The localization of ferrofluids was performed based on the analysis of quasirandom time series in two cases of oscillation source. One of them was infrasound from outer noise, and another one was the human heartbeat. These results are prospective for 3D imaging of magnetic particles without pre-magnetization.

  12. Computation of load performance and other parameters of extra high speed modified Lundell alternators from 3D-FE magnetic field solutions

    NASA Technical Reports Server (NTRS)

    Wang, R.; Demerdash, N. A.

    1992-01-01

    The combined magnetic vector potential - magnetic scalar potential method of computation of 3D magnetic fields by finite elements, introduced in a companion paper, in combination with state modeling in the abc-frame of reference, are used for global 3D magnetic field analysis and machine performance computation under rated load and overload condition in an example 14.3 kVA modified Lundell alternator. The results vividly demonstrate the 3D nature of the magnetic field in such machines, and show how this model can be used as an excellent tool for computation of flux density distributions, armature current and voltage waveform profiles and harmonic contents, as well as computation of torque profiles and ripples. Use of the model in gaining insight into locations of regions in the magnetic circuit with heavy degrees of saturation is demonstrated. Experimental results which correlate well with the simulations of the load case are given.

  13. Protecting ITER walls: fast ion power loads in 3D magnetic field

    NASA Astrophysics Data System (ADS)

    Kurki-Suonio, T.; Särkimäki, K.; Äkäslompolo, S.; Varje, J.; Liu, Y.; Sipilä, S.; Asunta, O.; Hirvijoki, E.; Snicker, A.; Terävä, J.; Cavinato, M.; Gagliardi, M.; Parail, V.; Saibene, G.

    2017-01-01

    The fusion alpha and beam ion with steady-state power loads in all four main operating scenarios of ITER have been evaluated by the ASCOT code. For this purpose, high-fidelity magnetic backgrounds were reconstructed, taking into account even the internal structure of the ferritic inserts and tritium breeding modules (TBM). The beam ions were found to be almost perfectly confined in all scenarios, and only the so-called hybrid scenario featured alpha loads reaching 0.5 MW due to its more triangular plasma. The TBMs were not found to jeopardize the alpha confinement, nor cause any hot spots. Including plasma response did not bring dramatic changes to the load. The ELM control coils (ECC) were simulated in the baseline scenario and found to seriously deteriorate even the beam confinement. However, the edge perturbation in this case is so large that the sources have to be re-evaluated with plasma profiles that take into account the ECC perturbation.

  14. Development of 3-D magnetic nano-arrays by electrodeposition into mesoporous silica.

    SciTech Connect

    Campbell, R.; Manning, J.; Bakker, M.G.; Li, X.; Lee, D.R.; Wang, J.; X-Ray Science Division; Univ. of Alabama

    2006-01-01

    The development of periodic nanostructures fabricated by self-assembly of surfactants and block co-polymers has opened up the possibility of generating periodic magnetic nanostructures of types not accessible by self-assembly of nano-particles. The fabrication of mesoporous silica thin films around self-assembled block co-polymers is well established. Common structures for such films are SBA-15 which consists of hexagonal arrays of cylindrical pores and SBA-16 which has face centered arrays of spherical voids. These pores are connected by 1-2 nm thick flaws in the continuous silica phase producing an effectively continuous porous phase. After removal of the block co-polymer template, electrodeposition into the mesoporous silica thin films produces arrays of 5-10 nm diameter nano-wires and nano-particles. We have demonstrated that such materials can be fabricated on a wide range of metal substrates. Characterization by Scanning Electron Microscopies shows that the mesoporous silica is well ordered over micron scale areas. Grazing Incidence Small Angle X-ray Scattering (GISAXS) studies shows diffraction spots, consistent with the entire film being well ordered. GISAXS also shows that the mesoporous silica films survive removal of the template and electrodeposition of nickel and cobalt into the mesoporous silica films. Such films are of interest for their magnetic properties, as the nanophase and scale can be independently varied. Further, the presence of nanowires inside an insulator suggests that these films might also be of interest as the current confining element for Confined Current Path-Current Perpendicular to Plane GMR sensors.

  15. Magnetic resonance of calcified tissues

    NASA Astrophysics Data System (ADS)

    Wehrli, Felix W.

    2013-04-01

    MRI of the human body is largely made possible by the favorable relaxation properties of protons of water and triacyl glycerides prevalent in soft tissues. Hard tissues - key among them bone - are generally less amenable to measurement with in vivo MR imaging techniques, not so much as a result of the lower proton density but rather due to the extremely short life-times of the proton signal in water bound to solid-like entities, typically collagen, or being trapped in micro-pores. Either mechanism can enhance T2 relaxation by up to three orders of magnitude relative to their soft-tissue counterparts. Detection of these protons requires solid-state techniques that have emerged in recent years and that promise to add a new dimension to the study of hard tissues. Alternative approaches to probe calcified tissues exploit their characteristic magnetic properties. Bone, teeth and extra-osseous calcium-containing biomaterials are unique in that they are more diamagnetic than all other tissues and thus yield information indirectly by virtue of the induced magnetic fields present in their vicinity. Progress has also been made in methods allowing very high-resolution structural imaging of trabecular and cortical bone relying on detection of the surrounding soft-tissues. This brief review, much of it drawn from work conducted in the author's laboratory, seeks to highlight opportunities with focus on early-stage developments for image-based assessment of structure, function, physiology and mechanics of calcified tissues in humans via liquid and solid-state approaches, including proton, deuteron and phosphorus NMR and MRI.

  16. Magnetic resonance of calcified tissues

    PubMed Central

    Wehrli, Felix W.

    2016-01-01

    MRI of the human body is largely made possible by the favorable relaxation properties of protons of water and triacyl glycerides prevalent in soft tissues. Hard tissues – key among them bone – are generally less amenable to measurement with in vivo MR imaging techniques, not so much as a result of the lower proton density but rather due to the extremely short life-times of the proton signal in water bound to solid-like entities, typically collagen, or being trapped in micro-pores. Either mechanism can enhance T2 relaxation by up to three orders of magnitude relative to their soft-tissue counterparts. Detection of these protons requires solid-state techniques that have emerged in recent years and that promise to add a new dimension to the study of hard tissues. Alternative approaches to probe calcified tissues exploit their characteristic magnetic properties. Bone, teeth and extra-osseous calcium-containing biomaterials are unique in that they are more diamagnetic than all other tissues and thus yield information indirectly by virtue of the induced magnetic fields present in their vicinity. Progress has also been made in methods allowing very high-resolution structural imaging of trabecular and cortical bone relying on detection of the surrounding soft-tissues. This brief review, much of it drawn from work conducted in the author’s laboratory, seeks to highlight opportunities with focus on early-stage developments for image-based assessment of structure, function, physiology and mechanics of calcified tissues in humans via liquid and solid-state approaches, including proton, deuteron and phosphorus NMR and MRI. PMID:23414678

  17. 21 CFR 892.1000 - Magnetic resonance diagnostic device.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... reflect frequency and distribution of nuclei exhibiting nuclear magnetic resonance. Other physical... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Magnetic resonance diagnostic device. 892.1000... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1000 Magnetic resonance...

  18. 21 CFR 892.1000 - Magnetic resonance diagnostic device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... reflect frequency and distribution of nuclei exhibiting nuclear magnetic resonance. Other physical... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Magnetic resonance diagnostic device. 892.1000... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1000 Magnetic resonance...

  19. 21 CFR 892.1000 - Magnetic resonance diagnostic device.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... reflect frequency and distribution of nuclei exhibiting nuclear magnetic resonance. Other physical... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Magnetic resonance diagnostic device. 892.1000... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1000 Magnetic resonance...

  20. 21 CFR 892.1000 - Magnetic resonance diagnostic device.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... reflect frequency and distribution of nuclei exhibiting nuclear magnetic resonance. Other physical... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Magnetic resonance diagnostic device. 892.1000... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1000 Magnetic resonance...

  1. 21 CFR 892.1000 - Magnetic resonance diagnostic device.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... reflect frequency and distribution of nuclei exhibiting nuclear magnetic resonance. Other physical... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Magnetic resonance diagnostic device. 892.1000... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1000 Magnetic resonance...

  2. [Magnetic resonance compatibility research for coronary mental stents].

    PubMed

    Wang, Ying; Liu, Li; Wang, Shuo; Shang, Ruyao; Wang, Chunren

    2015-01-01

    The objective of this article is to research magnetic resonance compatibility for coronary mental stents, and to evaluate the magnetic resonance compatibility based on laboratory testing results. Coronary stents magnetic resonance compatibility test includes magnetically induced displacement force test, magnetically induced torque test, radio frequency induced heating and evaluation of MR image. By magnetic displacement force and torque values, temperature, and image distortion values to determine metal coronary stent demagnetization effect. The methods can be applied to test magnetic resonance compatibility for coronary mental stents and evaluate its demagnetization effect.

  3. A hyperpolarized equilibrium for magnetic resonance.

    PubMed

    Hövener, Jan-Bernd; Schwaderlapp, Niels; Lickert, Thomas; Duckett, Simon B; Mewis, Ryan E; Highton, Louise A R; Kenny, Stephen M; Green, Gary G R; Leibfritz, Dieter; Korvink, Jan G; Hennig, Jürgen; von Elverfeldt, Dominik

    2013-01-01

    Nuclear magnetic resonance spectroscopy and imaging (MRI) play an indispensable role in science and healthcare but use only a tiny fraction of their potential. No more than ≈10 p.p.m. of all ¹H nuclei are effectively detected in a 3-Tesla clinical MRI system. Thus, a vast array of new applications lays dormant, awaiting improved sensitivity. Here we demonstrate the continuous polarization of small molecules in solution to a level that cannot be achieved in a viable magnet. The magnetization does not decay and is effectively reinitialized within seconds after being measured. This effect depends on the long-lived, entangled spin-order of parahydrogen and an exchange reaction in a low magnetic field of 10⁻³ Tesla. We demonstrate the potential of this method by fast MRI and envision the catalysis of new applications such as cancer screening or indeed low-field MRI for routine use and remote application.

  4. Magnetic resonance imaging with an optical atomicmagnetometer

    SciTech Connect

    Xu, Shoujun; Yashchuk, Valeriy V.; Donaldson, Marcus H.; Rochester, Simon M.; Budker, Dmitry; Pines, Alexander

    2006-05-09

    Magnetic resonance imaging (MRI) is a noninvasive andversatile methodology that has been applied in many disciplines1,2. Thedetection sensitivity of conventional Faraday detection of MRI depends onthe strength of the static magnetic field and the sample "fillingfactor." Under circumstances where only low magnetic fields can be used,and for samples with low spin density or filling factor, the conventionaldetection sensitivity is compromised. Alternative detection methods withhigh sensitivity in low magnetic fields are thus required. Here we showthe first use of a laser-based atomic magnetometer for MRI detection inlow fields. Our technique also employs remote detection which physicallyseparates the encoding and detection steps3-5, to improve the fillingfactor of the sample. Potentially inexpensive and using a compactapparatus, our technique provides a novel alternative for MRI detectionwith substantially enhanced sensitivity and time resolution whileavoiding the need for cryogenics.

  5. Normative biometry of the fetal brain using magnetic resonance imaging.

    PubMed

    Kyriakopoulou, Vanessa; Vatansever, Deniz; Davidson, Alice; Patkee, Prachi; Elkommos, Samia; Chew, Andrew; Martinez-Biarge, Miriam; Hagberg, Bibbi; Damodaram, Mellisa; Allsop, Joanna; Fox, Matt; Hajnal, Joseph V; Rutherford, Mary A

    2016-11-24

    The fetal brain shows accelerated growth in the latter half of gestation, and these changes can be captured by 2D and 3D biometry measurements. The aim of this study was to quantify brain growth in normal fetuses using Magnetic Resonance Imaging (MRI) and to produce reference biometry data and a freely available centile calculator ( https://www.developingbrain.co.uk/fetalcentiles/ ). A total of 127 MRI examinations (1.5 T) of fetuses with a normal brain appearance (21-38 gestational weeks) were included in this study. 2D and 3D biometric parameters were measured from slice-to-volume reconstructed images, including 3D measurements of supratentorial brain tissue, lateral ventricles, cortex, cerebellum and extra-cerebral CSF and 2D measurements of brain biparietal diameter and fronto-occipital length, skull biparietal diameter and occipitofrontal diameter, head circumference, transverse cerebellar diameter, extra-cerebral CSF, ventricular atrial diameter, and vermis height, width, and area. Centiles were constructed for each measurement. All participants were invited for developmental follow-up. All 2D and 3D measurements, except for atrial diameter, showed a significant positive correlation with gestational age. There was a sex effect on left and total lateral ventricular volumes and the degree of ventricular asymmetry. The 5th, 50th, and 95th centiles and a centile calculator were produced. Developmental follow-up was available for 73.1% of cases [mean chronological age 27.4 (±10.2) months]. We present normative reference charts for fetal brain MRI biometry at 21-38 gestational weeks. Developing growth trajectories will aid in the better understanding of normal fetal brain growth and subsequently of deviations from typical development in high-risk pregnancies or following premature delivery.

  6. 3-D laser confocal microscopy study of the oxidation of NdFeB magnets in atmospheric conditions

    NASA Astrophysics Data System (ADS)

    Meakin, J. P.; Speight, J. D.; Sheridan, R. S.; Bradshaw, A.; Harris, I. R.; Williams, A. J.; Walton, A.

    2016-08-01

    Neodymium iron boron (NdFeB) magnets are used in a number of important applications, such as generators in gearless wind turbines, motors in electric vehicles and electronic goods (e.g.- computer hard disk drives, HDD). Hydrogen can be used as a processing gas to separate and recycle scrap sintered Nd-Fe-B magnets from end-of-life products to form a powder suitable for recycling. However, the magnets are likely to have been exposed to atmospheric conditions prior to processing, and any oxidation could lead to activation problems for the hydrogen decrepitation reaction. Many previous studies on the oxidation of NdFeB magnets have been performed at elevated temperatures; however, few studies have been formed under atmospheric conditions. In this paper a combination of 3-D laser confocal microscopy and Raman spectroscopy have been used to assess the composition, morphology and rate of oxidation/corrosion on scrap sintered NdFeB magnets. Confocal microscopy has been employed to measure the growth of surface reaction products at room temperature, immediately after exposure to air. The results showed that there was a significant height increase at the triple junctions of the Nd-rich grain boundaries. Using Raman spectroscopy, the product was shown to consist of Nd2O3 and formed only on the Nd-rich triple junctions. The diffusion coefficient of the triple junction reaction product growth at 20 °C was determined to be approximately 4 × 10-13 cm2/sec. This value is several orders of magnitude larger than values derived from the diffusion controlled oxide growth observations at elevated temperatures in the literature. This indicates that the growth of the room temperature oxidation products are likely defect enhanced processes at the NdFeB triple junctions.

  7. 3D PIC Simulations of Collisionless Shocks at Lunar Magnetic Anomalies and Their Role in Forming Lunar Swirls

    NASA Astrophysics Data System (ADS)

    Bamford, R. A.; Alves, E. P.; Cruz, F.; Kellett, B. J.; Fonseca, R. A.; Silva, L. O.; Trines, R. M. G. M.; Halekas, J. S.; Kramer, G.; Harnett, E.; Cairns, R. A.; Bingham, R.

    2016-10-01

    Investigation of the lunar crustal magnetic anomalies offers a comprehensive long-term data set of observations of small-scale magnetic fields and their interaction with the solar wind. In this paper a review of the observations of lunar mini-magnetospheres is compared quantifiably with theoretical kinetic-scale plasma physics and 3D particle-in-cell simulations. The aim of this paper is to provide a complete picture of all the aspects of the phenomena and to show how the observations from all the different and international missions interrelate. The analysis shows that the simulations are consistent with the formation of miniature (smaller than the ion Larmor orbit) collisionless shocks and miniature magnetospheric cavities, which has not been demonstrated previously. The simulations reproduce the finesse and form of the differential proton patterns that are believed to be responsible for the creation of both the “lunar swirls” and “dark lanes.” Using a mature plasma physics code like OSIRIS allows us, for the first time, to make a side-by-side comparison between model and space observations. This is shown for all of the key plasma parameters observed to date by spacecraft, including the spectral imaging data of the lunar swirls. The analysis of miniature magnetic structures offers insight into multi-scale mechanisms and kinetic-scale aspects of planetary magnetospheres.

  8. 3D modelling of an aero-gravity and -magnetic survey as an first exploration step in a frontier basin

    NASA Astrophysics Data System (ADS)

    Köther, Nils; Eckard, Marcel; Götze, Hans-Jürgen

    2010-05-01

    The West African Taoudeni basin covers a desert area of about 1.8 million km² and is one of the last frontier basins worldwide. Here Wintershall Holding AG holds acreage of about 68000 km². During 2005-2007 geological surveys and an aero-gravity and -magnetic survey were conducted in this area. The potential field modelling should contribute first insight about the subsurface to plan an economic seismic survey. 2D models lead to poor results. 2008 the results of an internship (NK) were 3D subsurface models, which were enhanced during the following diploma thesis (Köther, 2009). Complex igneous rocks and sparsely distributed constraints lead to an ambiguous interpretation. Therefore, several simple 3D models were compiled with the in-house software IGMAS+, which base on geological ideas of the underground and fit well the measured data. These basic models allow a geophysical evaluation of different geological theories about the subsurface. Also, for a thorough interpretation field transformations (Euler, Curvature, and Derivatives) were calculated. These results led to new constraints for further interpretation of the basin structures and therefore they are important contributions for future exploration e.g. the planning of seismic surveys.

  9. A series of novel lanthanide carboxyphosphonates with a 3D framework structure: synthesis, structure, and luminescent and magnetic properties.

    PubMed

    Chen, Kai; Dong, Da-Peng; Sun, Zhen-Gang; Jiao, Cheng-Qi; Li, Chao; Wang, Cheng-Lin; Zhu, Yan-Yu; Zhao, Yan; Zhu, Jiang; Sun, Shou-Hui; Zheng, Ming-Jing; Tian, Hui; Chu, Wei

    2012-08-28

    By introduction of 1,4-benzenedicarboxylic acid as the second organic ligand, a series of novel lanthanide carboxyphosphonates with a 3D framework structure, namely, [Ln(3)(H(2)L)(HL)(2)(bdc)(2)(H(2)O)]·7H(2)O (Ln = La (1), Ce (2), Pr (3), Nd (4), Sm (5), Eu (6), Gd (7), Tb (8); H(3)L = H(2)O(3)PCH(2)NC(5)H(9)COOH; H(2)bdc = HOOCC(6)H(4)COOH) have been synthesized under hydrothermal conditions. Compounds are isostructural and feature a 3D framework in which Ln(III) polyhedra are interconnected by bridging {CPO(3)} tetrahedra into 2D inorganic layers parallel to the ab plane. The organic groups of H(2)L(-) are grafted on the two sides of the layer. These layers are further cross-linked by the bdc(2-) ligands from one layer to the Ln atoms from the other into a pillared-layered architecture with one-dimensional channel system along the a axis. The thermal stability of compounds has been investigated. Luminescent properties of compounds , and the magnetic properties of compound have also been studied.

  10. Interpretation of Magnetic Anomalies in Salihli (Turkey) Geothermal Area Using 3-D Inversion and Edge Detection Techniques

    NASA Astrophysics Data System (ADS)

    Timur, Emre

    2016-04-01

    There are numerous geophysical methods used to investigate geothermal areas. The major purpose of this magnetic survey is to locate the boudaries of active hydrothermal system in the South of Gediz Graben in Salihli (Manisa/Turkey). The presence of the hydrothermal system had already been inferred from surface evidence of hydrothermal activity and drillings. Firstly, 3-D prismatic models were theoretically investigated and edge detection methods were utilized with an iterative inversion method to define the boundaries and the parameters of the structure. In the first step of the application, it was necessary to convert the total field anomaly into a pseudo-gravity anomaly map. Then the geometric boudaries of the structures were determined by applying a MATLAB based software with 3 different edge detection algorithms. The exact location of the structures were obtained by using these boundary coordinates as initial geometric parameters in the inversion process. In addition to these methods, reduction to pole and horizontal gradient methods were applied to the data to achieve more information about the location and shape of the possible reservoir. As a result, the edge detection methods were found to be successful, both in the field and as theoretical data sets for delineating the boundaries of the possible geothermal reservoir structure. The depth of the geothermal reservoir was determined as 2,4 km from 3-D inversion and 2,1 km from power spectrum methods.

  11. Resonantly Detecting Axion-Mediated Forces with Nuclear Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Arvanitaki, Asimina; Geraci, Andrew A.

    2014-10-01

    We describe a method based on precision magnetometry that can extend the search for axion-mediated spin-dependent forces by several orders of magnitude. By combining techniques used in nuclear magnetic resonance and short-distance tests of gravity, our approach can substantially improve upon current experimental limits set by astrophysics, and probe deep into the theoretically interesting regime for the Peccei-Quinn (PQ) axion. Our method is sensitive to PQ axion decay constants between 109 and 1012 GeV or axion masses between 10-6 and 10-3 eV, independent of the cosmic axion abundance.

  12. Magnetic resonance imaging of the elbow.

    PubMed

    Stevens, Kathryn J

    2010-05-01

    Elbow pain is frequently encountered in clinical practice and can result in significant morbidity, particularly in athletes. Magnetic resonance imaging (MRI) is an excellent diagnostic imaging tool for the evaluation of soft tissue and osteochondral pathology around the elbow. Recent advances in magnetic field strength and coil design have lead to improved spatial resolution and superior soft tissue contrast, making it ideal for visualization of complex joint anatomy. This article describes the normal imaging appearances of anatomy around the elbow and reviews commonly occurring ligamentous, myotendinous, neural, and bursal pathology around the elbow.

  13. Antiferromagnetic resonance excitation by terahertz magnetic field resonantly enhanced with split ring resonator

    SciTech Connect

    Mukai, Y.; Hirori, H.; Yamamoto, T.; Kageyama, H.; Tanaka, K.

    2014-07-14

    Excitation of antiferromagnetic resonance (AFMR) in a HoFeO{sub 3} crystal combined with a split ring resonator (SRR) is studied using terahertz (THz) electromagnetic pulses. The magnetic field in the vicinity of the SRR is induced by the incident THz electric field component and excites spin oscillations that correspond to the AFMR, which are directly probed by the Faraday rotation of the polarization of a near-infrared probe pulse. The good agreement of the temperature-dependent magnetization dynamics with the calculation using the two-lattice Landau-Lifshitz-Gilbert equation confirms that the AFMR is excited by the THz magnetic field, which is enhanced at the SRR resonance frequency by a factor of 20 compared to the incident magnetic field.

  14. Human tooth and root canal morphology reconstruction using magnetic resonance imaging

    PubMed Central

    DRĂGAN, OANA CARMEN; FĂRCĂŞANU, ALEXANDRU ŞTEFAN; CÂMPIAN, RADU SEPTIMIU; TURCU, ROMULUS VALERIU FLAVIU

    2016-01-01

    Background and aims Visualization of the internal and external root canal morphology is very important for a successful endodontic treatment; however, it seems to be difficult considering the small size of the tooth and the complexity of the root canal system. Film-based or digital conventional radiographic techniques as well as cone beam computed tomography provide limited information on the dental pulp anatomy or have harmful effects. A new non-invasive diagnosis tool is magnetic resonance imaging, due to its ability of imaging both hard and soft tissues. The aim of this study was to demonstrate magnetic resonance imaging to be a useful tool for imaging the anatomic conditions of the external and internal root canal morphology for endodontic purposes. Methods The endodontic system of one freshly extracted wisdom tooth, chosen for its well-known anatomical variations, was mechanically shaped using a hybrid technique. After its preparation, the tooth was immersed into a recipient with saline solution and magnetic resonance imaged immediately. A Bruker Biospec magnetic resonance imaging scanner operated at 7.04 Tesla and based on Avance III radio frequency technology was used. InVesalius software was employed for the 3D reconstruction of the tooth scanned volume. Results The current ex-vivo experiment shows the accurate 3D volume rendered reconstruction of the internal and external morphology of a human extracted and endodontically treated tooth using a dataset of images acquired by magnetic resonance imaging. The external lingual and vestibular views of the tooth as well as the occlusal view of the pulp chamber, the access cavity, the distal canal opening on the pulp chamber floor, the coronal third of the root canals, the degree of root separation and the apical fusion of the two mesial roots, details of the apical region, root canal curvatures, furcal region and interradicular root grooves could be clearly bordered. Conclusions Magnetic resonance imaging offers 3

  15. [Cardiac magnetic resonance imaging of congenital heart defects in adults].

    PubMed

    Bastarrika Alemañ, G; Gavira Gómez, J J; Zudaire Díaz-Tejeiro, B; Castaño Rodríguez, S; Romero Ibarra, C; Sáenz de Buruaga, J D

    2007-01-01

    The study of congenital cardiopathies (CC) is one of the most clearly established indications of cardiac magnetic resonance imaging (CMRI). Different sequences, including anatomic, functional, flow (phase contrast), and 3D angiographic sequences, enable the diagnosis, treatment planning, and follow-up of these conditions. CMRI allows the anatomy, function, and alterations of flow in these cardiopathies to be evaluated in a single examination. Three-dimensional MR angiography enables the study of the great vessels and the anomalies associated to congenital heart defects in adults. This article describes an examination protocol and provides examples of MR images of the most common CC in adults: atrial septal defect, interventricular communication, atrioventricular canal, tetralogy of Fallot, transposition of the great arteries, congenitally corrected transposition of the great arteries, bicuspid aortic valve, subaortic stenosis, aortic coarctation, and Ebstein's anomaly.

  16. Proton magnetic resonance spectroscopy in multiple sclerosis

    SciTech Connect

    Wolinsky, J.S.; Narayana, P.A.; Fenstermacher, M.J. )

    1990-11-01

    Regional in vivo proton magnetic resonance spectroscopy provides quantitative data on selected chemical constituents of brain. We imaged 16 volunteers with clinically definite multiple sclerosis on a 1.5 tesla magnetic resonance scanner to define plaque-containing volumes of interest, and obtained localized water-suppressed proton spectra using a stimulated echo sequence. Twenty-five of 40 plaque-containing regions provided spectra of adequate quality. Of these, 8 spectra from 6 subjects were consistent with the presence of cholesterol or fatty acids; the remainder were similar to those obtained from white matter of normal volunteers. This early experience with regional proton spectroscopy suggests that individual plaques are distinct. These differences likely reflect dynamic stages of the evolution of the demyelinative process not previously accessible to in vivo investigation.

  17. Combined Confocal and Magnetic Resonance Microscopy

    SciTech Connect

    Wind, Robert A.; Majors, Paul D.; Minard, Kevin R.; Ackerman, Eric J.; Daly, Don S.; Holtom, Gary R.; Thrall, Brian D.; Weber, Thomas J.

    2002-05-12

    Confocal and magnetic resonance microscopy are both used to study live cells in a minimally invasive way. Both techniques provide complementary information. Therefore, by examining cells simultaneously with both methodologies, more detailed information is obtained than is possible with each of the microscopes individually. In this paper two configurations of a combined confocal and magnetic resonance microscope described. In both cases the sample compartment is part of a temperature regulated perfusion system. The first configuration is capable of studying large single cells or three-dimensional cell agglomerates, whereas with the second configuration monolayers of mammalian cells can be investigated . Combined images are shown of Xenopus laevis frog oocytes, model JB6 tumor spheroids, and a single layer of Chinese hamster ovary cells. Finally, potential applications of the combined microscope are discussed.

  18. Magnetic resonances in nano-scale metamaterials

    NASA Astrophysics Data System (ADS)

    Hao, Zhao; Liddle, Alex; Martin, Michael

    2006-03-01

    We have designed, fabricated, and optically measured several different kinds of nano-scale metamaterials. We make use e-beam nano-lithography technology at LBNL's Center for X-Ray Optics for fabricating these structures on extremely thin SiN substrates so that they are close to free-standing. Optical properties were measured as a function of incidence angle and polarization. We directly observe a strong magnetic resonance consistent with a negative magnetic permeability in our samples at mid- and near-IR optical frequencies. We will discuss the results in comparison with detailed simulations, and will discuss the electric dipole or quadrupole resonances observed in the samples. Finally, we will report on our progress towards constructing a fully negative index of refraction meta-material.

  19. Magnetic resonance imaging of diabetic foot complications

    PubMed Central

    Low, Keynes TA; Peh, Wilfred CG

    2015-01-01

    This pictorial review aims to illustrate the various manifestations of the diabetic foot on magnetic resonance (MR) imaging. The utility of MR imaging and its imaging features in the diagnosis of pedal osteomyelitis are illustrated. There is often difficulty encountered in distinguishing osteomyelitis from neuroarthropathy, both clinically and on imaging. By providing an accurate diagnosis based on imaging, the radiologist plays a significant role in the management of patients with complications of diabetic foot. PMID:25640096

  20. Neurosurgical uses for intraprocedural magnetic resonance imaging.

    PubMed

    Mutchnick, Ian S; Moriarty, Thomas M

    2005-10-01

    Neurosurgical procedures demand precision, and efforts to create accurate neurosurgical navigation have been central to the profession through its history. Magnetic resonance image (MRI)-guided navigation offers the possibility of real-time, image-based stereotactic information for the neurosurgeon, which makes possible a number of diagnostic and therapeutic procedures. This article will review both current options for intraoperative MRI operative suite arrangements and the current therapeutic/diagnostic uses of intraoperative MRI.

  1. Fluctuating magnetic field induced resonant activation

    SciTech Connect

    Mondal, Shrabani; Das, Sudip; Baura, Alendu; Bag, Bidhan Chandra

    2014-12-14

    In this paper, we have studied the properties of a Brownian particle at stationary state in the presence of a fluctuating magnetic field. Time dependence of the field makes the system thermodynamically open. As a signature of that the steady state distribution function becomes function of damping strength, intensity of fluctuations and constant parts of the applied magnetic field. It also depends on the correlation time of the fluctuating magnetic field. Our another observation is that the random magnetic field can induce the resonant activation phenomenon. Here correlation time is increased under the fixed variance of the fluctuating field. But if the correlation time (τ) increases under the fixed field strength then the mean first passage time rapidly grows at low τ and it almost converges at other limit. This is sharp contrast to the usual colored noise driven open system case where the mean first passage time diverges exponentially. We have also observed that a giant enhancement of barrier crossing rate occurs particularly at large strength of constant parts of the applied magnetic field even for very weak fluctuating magnetic field. Finally, break down of the Arrhenius result and disappearance of the Kramers’ turn over phenomenon may occur in the presence of a fluctuating magnetic field.

  2. Validation of the Model for ELM Suppression with 3D Magnetic Fields Using Low Torque ITER Baseline Scenario Discharges in DIII-D

    NASA Astrophysics Data System (ADS)

    Moyer, R. A.

    2016-10-01

    Suppression of Edge Localized Modes (ELMs) is lost in ITER Baseline Scenario discharges when the torque Tinj and toroidal rotation νϕ are reduced. This is due to a shift in the tearing response deeper into the plasma. ELM suppression is recovered by reducing the normalized plasma pressure βN. In H-mode plasmas, edge turbulence is suppressed in a ``pedestal'' region, leading to large pressure gradients that trigger MHD instabilities (ELMs), causing rapid heat expulsion. 3D magnetic fields are used to drive resonances that limit the pedestal width preventing the ELM. Reducing Tinj changes the νϕ profile such that the drive shifts to a resonance deeper in the plasma, allowing the pedestal to grow again to MHD instability. Reducing βN reduces the edge pressure, which reduces the electron diamagnetic flow and moves the drive to a resonance that is closer to the boundary, recovering suppression. In two-fluid theory, the tearing response occurs at a resonant surface where the electron perpendicular rotation ω (⊥ e) 0 . Linear two-fluid resistive MHD simulations show that the tearing response shifts to a resonance deeper in the plasma when Tinj is reduced. The experimental results confirm that the tearing response occurs for a resonance where ω (⊥ e) 0 , and suggest that the transport which limits the pedestal width is linked to the tearing response, even if any islands are predicted to be small. Although this model describes the differences between ELMing and ELM suppressed H-modes, it doesn't address the transition from ELMs to suppression, because ω (⊥ e) 0 is initially too deep (ψN <= 0.9, q = 3) for the tearing response to limit the pedestal width. Although understanding this transition is important, ITER must apply the RMP in L-mode to avoid the first ELM. These results suggest that manipulation of the edge rotation profile will be important to optimize ELM suppression in future tokamaks. Supported by the US DOE under DE-FG02-07ER54917 and DE-FG02

  3. Magnetic resonance venography and liver transplant complications.

    PubMed

    Strovski, Evgeny; Liu, Dave; Scudamore, Charles; Ho, Stephen; Yoshida, Eric; Klass, Darren

    2013-09-28

    Hepatic vein stenosis is a rare but serious complication following liver transplantation. Multiple modalities can be utilized to image the hepatic vasculature. Magnetic resonance venography (MRV) provides certain advantages over ultrasound, computed tomography angiography and digital subtraction venography. MRV utilizes the same imaging principles of magnetic resonance angiography in order to image the venous system. Blood pool contrast agents, specifically gadofosveset trisodium, allow for steady state imaging up to 1 h following injection, with improved visualisation of vital venous structures by utilising delayed steady state imaging. Additionally, the inherent physics properties of magnetic resonance imaging also provide excellent soft tissue detail and thus help define the extent of complications that often plague the post-liver transplant patient. This case report describes the use of gadofosveset trisodium in a patient with hepatic venous stenosis following liver transplantation. Initial venography failed to outline the stenoses and thus MRV using a blood pool contrast agent was utilised in order to delineate the anatomy and plan a therapeutic endovascular procedure.

  4. Magnetic resonance acoustic radiation force imaging.

    PubMed

    McDannold, Nathan; Maier, Stephan E

    2008-08-01

    Acoustic radiation force impulse imaging is an elastography method developed for ultrasound imaging that maps displacements produced by focused ultrasound pulses systematically applied to different locations. The resulting images are "stiffness weighted" and yield information about local mechanical tissue properties. Here, the feasibility of magnetic resonance acoustic radiation force imaging (MR-ARFI) was tested. Quasistatic MR elastography was used to measure focal displacements using a one-dimensional MRI pulse sequence. A 1.63 or 1.5 MHz transducer supplied ultrasound pulses which were triggered by the magnetic resonance imaging hardware to occur before a displacement-encoding gradient. Displacements in and around the focus were mapped in a tissue-mimicking phantom and in an ex vivo bovine kidney. They were readily observed and increased linearly with acoustic power in the phantom (R2=0.99). At higher acoustic power levels, the displacement substantially increased and was associated with irreversible changes in the phantom. At these levels, transverse displacement components could also be detected. Displacements in the kidney were also observed and increased after thermal ablation. While the measurements need validation, the authors have demonstrated the feasibility of detecting small displacements induced by low-power ultrasound pulses using an efficient magnetic resonance imaging pulse sequence that is compatible with tracking of a dynamically steered ultrasound focal spot, and that the displacement increases with acoustic power. MR-ARFI has potential for elastography or to guide ultrasound therapies that use low-power pulsed ultrasound exposures, such as drug delivery.

  5. Magnetic Resonance Imaging of Alimentary Tract Development in Manduca sexta

    PubMed Central

    Rowland, Ian J.; Goodman, Walter G.

    2016-01-01

    Non-invasive 3D magnetic resonance imaging techniques were used to investigate metamorphosis of the alimentary tract of Manduca sexta from the larval to the adult stage. The larval midgut contracts in volume immediately following cessation of feeding and then greatly enlarges during the late pharate pupal period. Magnetic resonance imaging revealed that the foregut and hindgut of the pharate pupa undergo ecdysis considerably earlier than the external exoskeleton. Expansion of air sacs in the early pupa and development of flight muscles several days later appear to orient the midgut into its adult position in the abdomen. The crop, an adult auxiliary storage organ, begins development as a dorsal outgrowth of the foregut. This coincides with a reported increase in pupal ecdysteroid titers. An outgrowth of the hindgut, the rectal sac, appears several days later and continues to expand until it nearly fills the dorsal half of the abdominal cavity. This development correlates with a second rise in pupal ecdysteroid titers. In the pharate pupa, the presence of paramagnetic species renders the silk glands hyperintense. PMID:27280776

  6. Bolometer detection of magnetic resonances in nanoscaled objects

    NASA Astrophysics Data System (ADS)

    Rod, Irina; Meckenstock, Ralf; Zähres, Horst; Derricks, Christian; Mushenok, Fedor; Reckers, Nathalie; Kijamnajsuk, Puchong; Wiedwald, Ulf; Farle, Michael

    2014-10-01

    We report on a nanoscaled thermocouple (ThC) as a temperature sensor of a highly sensitive bolometer for probing the dissipative damping of spin dynamics in nanosized Permalloy (Py) stripes. The Au-Pd ThC based device is fabricated by standard electron beam lithography on a 200 nm silicon nitride membrane to minimize heat dissipation through the substrate. We show that this thermal sensor allows not only measurements of the temperature change on the order of a few mK due to the uniform resonant microwave (MW) absorption by the Py stripe but also detection of standing spin waves of different mode numbers. Using a 3D finite element method, we estimate the absorbed MW power by the stripe in resonance and prove the necessity of using substrates with an extremely low heat dissipation like a silicon nitride membrane for successful thermal detection. The voltage responsivity and the noise equivalent power for the ThC-based bolometer are equal to 15 V W-1 and 3 nW Hz-1/2, respectively. The ThC device offers a magnetic resonance response of 1 nV/(μB W) corresponding to a sensitivity of 109 spins and a temperature resolution of 300 μK under vacuum conditions.

  7. Segmentation of multidimensional magnetic resonance (MR) images using a fuzzy neural network

    NASA Astrophysics Data System (ADS)

    Ma, Jesse C.; Rodriguez, Jeffrey J.

    1994-09-01

    Methods of 3-D visualization of the brain based on fuzzy c-means (FCM) classified magnetic resonance (MR) images and a neural network trained on the FCM data are presented. A 3-D MR scan of a volunteer serves as the basis for the unsupervised classification techniques. The images were first classified into different tissue types by using FCM. The classified images were then reconstructed for 3-D display. Results show that individual tissue types can be discriminated during the 3-D rendering process. A neural network trained on the fuzzy classification data was also implemented. By using the cascade correlation algorithm during the network training, much of the tedious training work was avoided. The preliminary results from the neural network approach are quite encouraging.

  8. Toxicity evaluation of magnetic hyperthermia induced by remote actuation of magnetic nanoparticles in 3D micrometastasic tumor tissue analogs for triple negative breast cancer.

    PubMed

    Stocke, Nathanael A; Sethi, Pallavi; Jyoti, Amar; Chan, Ryan; Arnold, Susanne M; Hilt, J Zach; Upreti, Meenakshi

    2017-03-01

    Magnetic hyperthermia as a treatment modality is acquiring increased recognition for loco-regional therapy of primary and metastatic lung malignancies by pulmonary delivery of magnetic nanoparticles (MNP). The unique characteristic of magnetic nanoparticles to induce localized hyperthermia in the presence of an alternating magnetic field (AMF) allows for preferential killing of cells at the tumor site. In this study we demonstrate the effect of hyperthermia induced by low and high dose of MNP under the influence of an AMF using 3D tumor tissue analogs (TTA) representing the micrometastatic, perfusion independent stage of triple negative breast cancer (TNBC) that infiltrates the lungs. While application of inhalable magnetic nanocomposite microparticles or magnetic nanocomposites (MnMs) to the micrometastatic TNBC model comprised of TTA generated from cancer and stromal cells, showed no measureable adverse effects in the absence of AMF-exposure, magnetic hyperthermia generated under the influence of an AMF in TTA incubated in a high concentration of MNP (1 mg/mL) caused significant increase in cellular death/damage with mechanical disintegration and release of cell debris indicating the potential of these inhalable composites as a promising approach for thermal treatment of diseased lungs. The novelty and significance of this study lies in the development of methods to evaluate in vitro the application of inhalable composites containing MNPs in thermal therapy using a physiologically relevant metastatic TNBC model representative of the microenvironmental characteristics in secondary lung malignancies.

  9. Artifacts in magnetic resonance imaging from metals

    NASA Astrophysics Data System (ADS)

    Bennett, L. H.; Wang, P. S.; Donahue, M. J.

    1996-04-01

    Metallic biomedical implants, such as aneurysm clips, endoprostheses, and internal orthopedic devices give rise to artifacts in the magnetic resonance image (MRI) of patients. Such artifacts impair the information contained in the image in precisely the region of most interest, namely near the metallic device. Ferromagnetic materials are contraindicated because of the hazards associated with their movement during the MRI procedure. In less-magnetic metals, it has been suggested that the extent of the artifact is related to the magnetic susceptibility of the metal, but no systematic data appear to be available. When the susceptibility is sufficiently small, an additional artifact due to electrical conductivity is observed. We present an initial systematic study of MRI artifacts produced by two low susceptibility metals, titanium (relative permeability μr≊1.0002) and copper (μr≊0.99998), including experimental, theoretical, and computer simulation results.

  10. Magnetic Tweezers-based 3D Microchannel Electroporation for High-Throughput Gene Transfection in Living Cells

    PubMed Central

    Liao, Wei-Ching; Chiang, Chi-Ling; Gallego-Perez, Daniel; Yang, Zhaogang; Lu, Wu; Byrd, John C.; Muthusamy, Natarajan; Lee, L. James.; Sooryakumar, Ratnasingham

    2015-01-01

    We report a novel, high throughput magnetic-tweezers based 3D microchannel electroporation system capable of transfecting 40,000 cells/cm2 on a single-chip for gene therapy, regenerative medicine and intracellular detection of target mRNA for screening cellular heterogeneity. A single cell or an ordered array of individual cells are remotely guided by programmable magnetic fields to poration sites with high (> 90%) cell alignment efficiency to enable various transfection reagents to be delivered simultaneously into the cells. The present technique, in contrast to the conventional vacuum based approach, is significantly gentler on the cellular membrane yielding > 90% cell viability and, moreover, allows transfected cells to be transported for further analysis. Illustrating the versatility of the system, the GATA2 molecular beacon was delivered into leukemia cells to detect the regulation level of the GATA2 gene that is associated with the initiation of leukemia. The uniform delivery and a sharp contrast of fluorescence intensity between GATA2 positive and negative cells demonstrate key as