Science.gov

Sample records for 3-month observation period

  1. Observed coparenting and triadic dynamics in African American fragile families at 3 months' postpartum.

    PubMed

    McHale, James P; Coates, Erica E

    2014-01-01

    This report examines coparenting and triadic interactions in 19 unmarried, first-time African American families as fathers, mothers, and 3-month-old infants navigated the Lausanne Trilogue Play (LTP; E. Fivaz-Depeursinge & A. Corboz-Warnery, ). Parents in 10 of the 19 families reported coresidence at the time of the 3-month assessment, and the other 9 sets of coparents lived apart. All participating families had taken part in a prenatal intervention emphasizing the importance of father engagement in children's lives, and in all families, parents reported episodic to regular father contact with the children at 3 months. Analyses of LTP sessions revealed that 9 of the 19 families exhibited high levels of coparenting solidarity-cooperation and family warmth accompanied by low levels of coparenting competition and disengagement. Among the remaining 10 families, competitiveness (verbal sparring, interference) and/or disengagement (repeated, episodic absenting by one or both parents from the ongoing interaction) signaled strain and challenges to solidarity. Differences between the higher and lower solidarity groups were found in father-reported relationship rapport. However, coresidentiality versus noncoresidentiality of the parents did not distinguish high- from low-solidarity groups. A case analysis of one family's triadic session is presented to elucidate the rich potential for clinical intervention in triadic work with fragile family systems. Implications of the study and its findings for theory, research, and clinical work with unmarried fathers and families, along with limits of the study design and generalizability of findings, are discussed.

  2. Video Evidence That London Infants Can Resettle Themselves Back to Sleep After Waking in the Night, as well as Sleep for Long Periods, by 3 Months of Age

    PubMed Central

    Hovish, Kimberly; Owen, Charlie

    2015-01-01

    ABSTRACT: Objective: Most infants become settled at night by 3 months of age, whereas infants not settled by 5 months are likely to have long-term sleep-waking problems. We assessed whether normal infant development in the first 3 months involves increasing sleep-period length or the ability to resettle autonomously after waking in the night. Methods: One hundred one infants were assessed at 5 weeks and 3 months of age using nighttime infrared video recordings and parental questionnaires. Results: The clearest development was in sleep length; 45% of infants slept continuously for ≥5 hours at night at 3 months compared with 10% at 5 weeks. In addition, around a quarter of infants woke and resettled themselves back to sleep in the night at each age. Autonomous resettling at 5 weeks predicted prolonged sleeping at 3 months suggesting it may be a developmental precursor. Infants reported by parents to sleep for a period of 5 hours or more included infants who resettled themselves and those with long sleeps. Three-month olds fed solely breast milk were as likely to self-resettle or have long sleep bouts as infants fed formula or mixed breast and formula milk. Conclusions: Infants are capable of resettling themselves back to sleep in the first 3 months of age; both autonomous resettling and prolonged sleeping are involved in “sleeping through the night” at an early age. Findings indicate the need for physiological studies of how arousal, waking, and resettling develop into sustained sleeping and of how environmental factors support these endogenous and behavioral processes. PMID:26035139

  3. 3-Month Results from Denmark within the Globally Prospective and Observational Study to Evaluate Insulin Detemir Treatment in Type 1 and Type 2 Diabetes: The PREDICTIVE Study

    PubMed Central

    Hermansen, Kjeld; Lund, Per; Clemmensen, Kurt; Breum, Leif; Kleis Moller, Marianne; Mette Rosenfalck, Anne; Christiansen, Erik; on behalf of the Danish PREDICTIVE study group

    2007-01-01

    PREDICTIVE™ is a large, multi-national, open-label, prospective, observational study to assess the efficacy and safety of insulin detemir in clinical practice. We report 3-month follow-up data from 389 patients with type 1 (n = 312) and type 2 (n = 77) diabetes from Denmark. Insulin detemir improved glycemic control in type 1 patients, with decreases in mean HbA1c (-0.2%, p = 0.0026), fasting glucose (-1.7 mmol/l, p = 0.0033) and within-patient fasting glucose variability (-0.6 mmol/l, p = 0.0472). Non-significant reductions in glycemic parameters were observed in type 2 patients (-0.3% for HbA1c and -2.7 mmol/l for fasting glucose). There was a decrease in mean body weight in both type 1 and type 2 patients (-0.6 kg, p = 0.025 and -1.0 kg, p = 0.0361, respectively). Three patients (0.8%) reported 4 serious adverse drug reactions, including major hypoglycemia. The incidence of major hypoglycemic episodes was reduced from 3.9/patient-years at baseline to 0.4/patient-years at follow-up in type 1 patients (p < 0.0001), and from 1.0 to 0.0/patient-years in type 2 patients (p = 0.1250). In addition, the mean incidence of total and nocturnal hypoglycemic episodes was reduced in both type 1 (-37.4 and -17.7/patient-years, p < 0.0001 for both) and type 2 patients (-17.7 and -7.8/patient-years, p = 0.0012 and p = 0.0020, respectively). The observations from the Danish cohort of the PREDICTIVE study support the overall findings of PREDICTIVE, i.e. insulin detemir improves glycemic control, with a reduced risk of hypoglycemia and no weight gain. PMID:17823693

  4. Usability, Participant Acceptance, and Safety of a Prefilled Insulin Injection Device in a 3-Month Observational Survey in Everyday Clinical Practice in Australia

    PubMed Central

    Carter, John; Beilin, Jonathan; Morton, Adam; De Luise, Mario

    2009-01-01

    Background SoloSTAR® (SOL; sanofi-aventis, Paris, France) is a prefilled insulin pen device for the injection of insulin glargine and insulin glulisine. This is the first Australian survey to determine its usability, participant acceptance, and safety in clinical practice. Methods A 3-month, nonrandomized, noncomparative, observational survey in Australia was conducted in individuals with diabetes. Participants were given SOL pens containing glargine, the instruction leaflet, and a toll-free helpline number. Training was offered to all participants. Safety data, including product technical complaints (PTCs), were gathered from ongoing feedback given by the participant or health care professional (HCP) and by independent interviews conducted 6–10 weeks after study start. Results Some 2674 people consented to take part across 93 sites (150 HCPs), and 2029 participated in interviews. Of these, 52.6% had type 1 diabetes, 16.3% had manual dexterity problems, and 15.5% had poor eyesight not corrected by glasses. At the time of interview, 96.8% of participants were still using SOL. None of the eight PTCs reported were due to technical defects; most were related to handling errors. Some 62 participants reported 77 adverse events; none were related to a PTC. The vast majority of participants (95.4%) were “very satisfied” or “satisfied” with using SOL, and 89.7% of the participants had no questions or concerns using SOL on a daily basis. Similar positive findings were reported by participants with manual or dexterity impairments. Conclusions In this survey of everyday clinical practice, SOL had a good safety profile and was very well accepted by participants. PMID:20144398

  5. A model study of the pollution effects of the first 3 months of the Holuhraun volcanic fissure: comparison with observations and air pollution effects

    NASA Astrophysics Data System (ADS)

    Steensen, Birthe Marie; Schulz, Michael; Theys, Nicolas; Fagerli, Hilde

    2016-08-01

    Norway, a region with frequent precipitation during westerly winds. Over a 3-month average (during SON 2014) over Europe, SO2 and PM2.5 surface concentrations, due to the volcanic emissions, increased by only ten and 6 % respectively. Although the percent increase of PM2.5 concentration is highest over Scandinavia and Scotland, an increase in PM exceedance days is found over Ireland and the already polluted Benelux region (up to 3 additional days), where any small increase in particulate matter concentration leads to an increase in exceedance days.

  6. Mother's stress, mood and emotional involvement with the infant: 3 months before and 3 months after childbirth.

    PubMed

    Figueiredo, Barbara; Costa, Raquel

    2009-06-01

    Adverse effects of maternal anxiety and depression are well documented, namely on the foetus/child behaviour and development, but not as much attention has been given to the mother's emotional involvement with the offspring. To study mother's prenatal and postpartum stress, mood and emotional involvement with the infant, the State-Trait Anxiety Inventory, the Edinburgh Postnatal Depression Scale and the Mother-to-Infant Bonding Scale were filled in and cortisol levels were measured, 3 months before and 3 months after childbirth, in a sample of 91 Portuguese women. From pregnancy to the postpartum period, mother's cortisol levels, anxiety and emotional involvement toward the child decrease. No significant change was observed regarding mother's depression. Mother's depression predicted a worse emotional involvement before childbirth, while mother's anxiety predicted a worse emotional involvement with the infant after childbirth. Additionally, pregnant women with a worse emotional involvement with the offspring are at risk of poorer emotional involvement with the infant and higher anxiety and depression at 3 months postpartum. It should be given more attention to mother's poor emotional involvement with the offspring during pregnancy, as it interferes with her emotional involvement with the infant and her psychological adjustment 3 months after childbirth.

  7. Infant Development: Birth to 3 Months

    MedlinePlus

    ... major infant development milestones from birth to 3 months — and know what to do when something's not ... A lot happens during your baby's first three months. Most babies reach certain milestones at similar ages, ...

  8. The international seismological observing period in Africa

    USGS Publications Warehouse

    Engdahl, E.R.; Bergman, Eric A.

    1992-01-01

    The International Seismological Observing Period (ISOP) is a specific time interval designated for enhanced international cooperation in the collection and dissemination of observatory measurements from the global seismographic network. The primary purpose of the ISOP is to strengthen the international infrastructure that supports current seismological practice and increase the cooperation among nations that operate seismological observatories. Measurements, reported by the existing global network and compiled by agencies such as the International Seismological Centre (ISC), are providing new information about earthquakes and the structure of the Earth of fundamental importance to the Earth sciences. However, these data represent but a small fraction of the information contained in the seismograms. One of the goals of the ISOP is to collect improved sets of data. In particular, the measurement and reporting of later-arriving phases, during a fixed ISOP period, from earthquakes selected for detailed observation by the cooperating stations will be encouraged. The use of advanced, digital instrumentation provides an unprecedented opportunity for enhancing the methods of seismogram interpretation and seismic parameter extraction, by the implementation of digital processing methods at seismic observatories worldwide. It must be ensured that this new information will be available to the entire seismological community. It is believed that this purpose is best served with an ISOP that promotes increased on-site processing at digital stations in Africa and elsewhere. Improvements in seismology require truly international cooperation and the educational aspects of seismological practice form one of the goals of the ISOP. Thus, workshops will be needed in Africa to train analysts in ISOP procedures and to introduce them to modern techniques and applications of the data. Participants will, thus, benefit from theoretical results and practical experience that are of direct

  9. 9 CFR 206.3 - Monthly report.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.3 Monthly report. (a) Do I need... swine processing plant that it operates or at which it has swine slaughtered that has the slaughtering... report, each packer must provide the following information: (1) Number of swine to be delivered...

  10. Feeding Your 1- to 3-Month-Old

    MedlinePlus

    ... 2-Year-Old Feeding Your 1- to 3-Month-Old KidsHealth > For Parents > Feeding Your 1- to 3-Month-Old A A A en español Alimentar a ... meses de edad During your baby's first 3 months, breast milk or formula will provide all the ...

  11. Feeding Your 1- to 3-Month-Old

    MedlinePlus

    ... 2-Year-Old Feeding Your 1- to 3-Month-Old KidsHealth > For Parents > Feeding Your 1- to 3-Month-Old Print A A A en español Alimentar ... meses de edad During your baby's first 3 months, breast milk or formula will provide all the ...

  12. Cardiometabolic Health in Submariners Returning from a 3-Month Patrol

    PubMed Central

    Gasier, Heath G.; Young, Colin R.; Gaffney-Stomberg, Erin; McAdams, Douglas C.; Lutz, Laura J.; McClung, James P.

    2016-01-01

    Confined space, limited exercise equipment, rotating shift work and reduced sleep may affect cardiometabolic health in submariners. To test this hypothesis, 53 male U.S. Submariners (20–39 years) were studied before and after a 3-month routine submarine patrol. Measures included anthropometrics, dietary and physical activity, biomarkers of cardiometabolic health, energy and appetite regulation, and inflammation. Before deployment, 62% of submariners had a body fat % (BF%) ≥ 25% (obesity), and of this group, 30% met the criteria for metabolic syndrome. In obese volunteers, insulin, the homeostatic model assessment of insulin resistance (HOMA-IR), leptin, the leptin/adiponectin ratio, and pro-inflammatory chemokines growth-related oncogene and macrophage-derived chemokine were significantly higher compared to non-obese submariners. Following the patrol, a significant mean reduction in body mass (5%) and fat-mass (11%) occurred in the obese group as a result of reduced energy intake (~2000 kJ) during the patrol; and, independent of group, modest improvements in serum lipids and a mean reduction in interferon γ-induced protein 10 and monocyte chemotactic protein 1 were observed. Since 43% of the submariners remained obese, and 18% continued to meet the criteria for metabolic syndrome following the patrol, the magnitude of weight loss was insufficient to completely abolish metabolic dysfunction. Submergence up to 3-months, however, does not appear to be the cause of obesity, which is similar to that of the general population. PMID:26867201

  13. Periodic Properties and Inquiry: Student Mental Models Observed during a Periodic Table Puzzle Activity

    ERIC Educational Resources Information Center

    Larson, Kathleen G.; Long, George R.; Briggs, Michael W.

    2012-01-01

    The mental models of both novice and advanced chemistry students were observed while the students performed a periodic table activity. The mental model framework seems to be an effective way of analyzing student behavior during learning activities. The analysis suggests that students do not recognize periodic trends through the examination of…

  14. Optimizing observing sequence design for periodic and non-periodic phenomena : a Bayesian approach

    NASA Technical Reports Server (NTRS)

    Johnston, Mark D.; Knight, Russell

    2005-01-01

    In this paper we report on our progress on addressing these issues. We have developed an approximate expression for the uniformity of phase coverage that can be used when scheduling to assess candidate sample times. We describe the results obtained using this estimator, and compare them with detailed simulations. We describe our progress and plans for integrating optimizing criteria for both periodic and non-periodic observations into a single observation sequence.

  15. Medical Care and Your 1- to 3-Month-Old

    MedlinePlus

    ... Old Medical Care and Your 1- to 3-Month-Old KidsHealth > For Parents > Medical Care and Your 1- to 3-Month-Old A A A What's in this article? ... When to Call the Doctor During these early months, you might have many questions about your baby's ...

  16. Learning, Play, and Your 1- to 3-Month-Old

    MedlinePlus

    ... Old Learning, Play, and Your 1- to 3-Month-Old KidsHealth > For Parents > Learning, Play, and Your 1- to 3-Month-Old A A A What's in this article? ... start responding even more to you during these months — and will even give you a smile! Babies ...

  17. Learning, Play, and Your 1- to 3-Month-Old

    MedlinePlus

    ... Old Learning, Play, and Your 1- to 3-Month-Old KidsHealth > For Parents > Learning, Play, and Your 1- to 3-Month-Old Print A A A What's in this ... start responding even more to you during these months — and will even give you a smile! Babies ...

  18. Medical Care and Your 1- to 3-Month-Old

    MedlinePlus

    ... Old Medical Care and Your 1- to 3-Month-Old KidsHealth > For Parents > Medical Care and Your 1- to 3-Month-Old Print A A A What's in this ... When to Call the Doctor During these early months, you might have many questions about your baby's ...

  19. Origin of Observed Periodic Components in Astrophysical Masers' Spectra

    NASA Astrophysics Data System (ADS)

    Siparov, S.; Samodurov, V.; Laptev, G.

    2017-01-01

    Further analysis of data previously obtained during the monitoring observations of 49 astrophysical water (22 GHz) masers shows that in some cases the intensity of an individual component of the maser spectrum changes periodically, on timescales of tens of minutes. It is argued that this variation cannot be the effect of instrumental errors, weather conditions or interstellar medium instabilities, because only a single feature of the maser spectrum fluctuates but not the whole spectrum. The suggested interpretation of this effect is based on the optic-metrical parametric resonance produced by gravitational radiation emitted by short-period binary stars, with the examples of such binaries sufficing the conditions given.

  20. Senses and Your 1- to 3-Month-Old

    MedlinePlus

    ... the Classroom What Other Parents Are Reading Your Child's Development (Birth to 3 Years) Feeding Your 1- to ... and Your 1- to 3-Month-Old Your Child’s Development: 1 Month Contact Us Print Resources Send to ...

  1. Saturn's planetary period oscillations observed during 10 years of Cassini

    NASA Astrophysics Data System (ADS)

    Provan, Gabrielle; Andrews, David; Cowley, Stanley; Dougherty, Michele

    2014-05-01

    Planetary period oscillations (PPOs) with periods close to Saturn's rotational period are ubiquitous throughout Saturn's magnetospheric system. Here we review the observational studies of PPOs determined from magnetospheric magnetic field data throughout the Cassini mission to date. As first shown using radio data, two oscillatory systems are present, one associated with the northern polar region and the other with the southern. We show that within the northern (southern) open-field polar region only the northern (southern) PPO oscillations are detected. However, within the equatorial 'core' region of Saturn's magnetosphere (dipole L ≤ 12), the two oscillations are superposed and interfere. The PPO periods are shown to lie in the range ~10.6 to 10.8 h, are persistently shorter north than south to date, and undergo a strong seasonal cycle together with the oscillation amplitudes. We discuss these observations in relation to theoretical models that have been proposed to explain them, and emphasize the importance of continued measurement of their properties during the Cassini solstice mission.

  2. Independent Predictors of Recovery of Continence 3 Months After Robot-Assisted Laparoscopic Radical Prostatectomy

    PubMed Central

    Kim, Jung Jun; Ha, Yun-Sok; Kim, Jeong Hyun; Jeon, Seong Soo; Lee, Dong-Hyeon; Kim, Wun-Jae

    2012-01-01

    Abstract Purpose To investigate the factors that predict recovery of continence within 3 months after robot-assisted radical prostatectomy (RARP). Patients and Methods The charts of 452 patients who underwent RARP with a minimum follow-up period of 3 months were collected prospectively and reviewed retrospectively. Urinary continence was determined using the self-administered validated Expanded Prostate Cancer Index Composite questionnaire during the routine follow-up visits. Results The overall continence rate 3 months after RARP was 79.9%. In an univariate logistic regression test, age<70 years, higher preoperative Sexual Health Inventory for Men (SHIM) score, lower clinical T1 stage, lower biopsy and pathologic Gleason score, shorter operative time, lower estimated blood loss, smaller prostate volume (<40 cc) were associated with recovery of urinary continence within 3 months after RARP (P<0.05). In multivariate logistic regression analysis, younger age, higher SHIM score, lower clinical T1 stage, lower body mass index (BMI), and smaller prostate volume were independent factors that predicted return of continence within 3 months after RARP (P<0.05). Conclusions Younger age (<70 years), higher preoperative SHIM score, clinical T1 stage, lower BMI, and smaller prostate volume (<40 cc) independently predicted recovery of continence within 3 months after RARP. PMID:22651546

  3. Paliperidone Palmitate Intramuscular 3-Monthly Formulation: A Review in Schizophrenia.

    PubMed

    Lamb, Yvette N; Keating, Gillian M

    2016-10-01

    A 3-monthly formulation of intramuscular paliperidone palmitate (3-monthly paliperidone palmitate) has recently been approved for the maintenance treatment of schizophrenia in adult patients in the EU (Trevicta(®)), following earlier approval in the USA (Invega Trinza(®)). This narrative review discusses the clinical use of 3-monthly paliperidone palmitate in the maintenance treatment of schizophrenia in adult patients and summarizes its pharmacological properties. The efficacy of the 3-monthly paliperidone palmitate formulation as a maintenance treatment for schizophrenia has been demonstrated in well designed, phase III trials. Three-monthly paliperidone palmitate was more effective than placebo in delaying time to relapse and reducing relapse rates, and was noninferior to 1-monthly paliperidone palmitate in the proportion of patients that remained relapse-free. The 3-monthly formulation was also more effective than placebo in controlling the symptoms of schizophrenia, whilst not differing significantly from the 1-monthly formulation in terms of symptomatic control. Three-monthly paliperidone palmitate was generally well tolerated in clinical trials, with a tolerability profile consistent with that of the 1-monthly formulation. In conclusion, 3-monthly paliperidone palmitate is a useful treatment option for adult patients with schizophrenia who are adequately treated with the 1-monthly formulation, particularly for those who would prefer, or may benefit from, longer dosing intervals.

  4. Aerosol classification using EARLINET measurements for an intensive observational period

    NASA Astrophysics Data System (ADS)

    Papagiannopoulos, Nikolaos; Mona, Lucia; Pappalardo, Gelsomina

    2016-04-01

    ACTRIS (Aerosols, Clouds and Trace gases Research Infrastructure Network) organized an intensive observation period during summer 2012. This campaign aimed at the provision of advanced observations of physical and chemical aerosol properties, at the delivery of information about the 3D distribution of European atmospheric aerosols, and at the monitoring of Saharan dust intrusions events. EARLINET (European Aerosol Research Lidar Network) participated in the ACTRIS campaign through the addition of measurements according to the EARLINET schedule as well as daily lidar-profiling measurements around sunset by 11 selected lidar stations for the period from 8 June - 17 July. EARLINET observations during this almost two-month period are used to characterize the optical properties and vertical distribution of long-range transported aerosol over the broader area of Mediterranean basin. The lidar measurements of aerosol intensive parameters (lidar ratio, depolarization, Angstrom exponents) are shown to vary with location and aerosol type. A methodology based on EARLINET observations of frequently observed aerosol types is used to classify aerosols into seven separate types. The summertime Mediterranean basin is prone to African dust aerosols. Two major dust events were studied. The first episode occurred from the 18 to 21 of the June and the second one lasted from 28 June to 6 July. The lidar ratio within the dust layer was found to be wavelength independent with mean values of 58±14 sr at 355 nm and 57±11 sr at 532 nm. For the particle linear depolarization ratio, mean values of 0.27±0.04 at 532 nm have been found. Acknowledgements. The financial support for EARLINET in the ACTRIS Research Infrastructure Project by the European Union's Horizon 2020 research and innovation programme under grant agreement no. 654169 and previously under grant agreement no. 262254 in the Seventh Framework Programme (FP7/2007-2013) is gratefully acknowledged.

  5. The Search for Periodic Components in Observational Data

    NASA Astrophysics Data System (ADS)

    Baluev, R. V.

    2014-09-01

    This review is devoted to the problem of searching for periodicities in observational data using periodograms based on the general statistical likelihood ratio test and special variants of it, including the classical Lomb-Scargle periodogram. Primary emphasis is on the problem of estimating the statistical significance of the periodicities detected in this manner. We assume that a universal solution of this problem exists involving an effective method in which the periodogram is regarded as a random process (or random field), while an approximation for the required "false alarm probability" is constructed by a generalized Rice method. Besides a unified method for determining the expected noise levels (or significance levels) of these periodograms, we also examine some important special cases with different models of periodic signals (linear and nonlinear). The false alarm probability associated with an observed signal is approximated in most cases by a formula of the type , where z is the observed maximum readout in the periodogram and P is an algebraic polynomial with coefficients that depend on the conditions of the problem. We also examine the problem of separating composite signals with several frequencies from noise. In this case correct analysis of the data requires the use of so-called multifrequency periodograms based on models of signals containing several periodic components. We show that a complete solution to this problem requires construction of 2n-1 such periodograms, where n is the total number of possible frequencies. Finally, we describe some program packages that we have developed which make it easier to perform practical frequency analysis of series using this theory.

  6. Earthquake nucleation mechanisms and periodic loading: Models, Experiments, and Observations

    NASA Astrophysics Data System (ADS)

    Dahmen, K.; Brinkman, B.; Tsekenis, G.; Ben-Zion, Y.; Uhl, J.

    2010-12-01

    The project has two main goals: (a) Improve the understanding of how earthquakes are nucleated ¬ with specific focus on seismic response to periodic stresses (such as tidal or seasonal variations) (b) Use the results of (a) to infer on the possible existence of precursory activity before large earthquakes. A number of mechanisms have been proposed for the nucleation of earthquakes, including frictional nucleation (Dieterich 1987) and fracture (Lockner 1999, Beeler 2003). We study the relation between the observed rates of triggered seismicity, the period and amplitude of cyclic loadings and whether the observed seismic activity in response to periodic stresses can be used to identify the correct nucleation mechanism (or combination of mechanisms). A generalized version of the Ben-Zion and Rice model for disordered fault zones and results from related recent studies on dislocation dynamics and magnetization avalanches in slowly magnetized materials are used in the analysis (Ben-Zion et al. 2010; Dahmen et al. 2009). The analysis makes predictions for the statistics of macroscopic failure events of sheared materials in the presence of added cyclic loading, as a function of the period, amplitude, and noise in the system. The employed tools include analytical methods from statistical physics, the theory of phase transitions, and numerical simulations. The results will be compared to laboratory experiments and observations. References: Beeler, N.M., D.A. Lockner (2003). Why earthquakes correlate weakly with the solid Earth tides: effects of periodic stress on the rate and probability of earthquake occurrence. J. Geophys. Res.-Solid Earth 108, 2391-2407. Ben-Zion, Y. (2008). Collective Behavior of Earthquakes and Faults: Continuum-Discrete Transitions, Evolutionary Changes and Corresponding Dynamic Regimes, Rev. Geophysics, 46, RG4006, doi:10.1029/2008RG000260. Ben-Zion, Y., Dahmen, K. A. and J. T. Uhl (2010). A unifying phase diagram for the dynamics of sheared solids

  7. ISO spectroscopic observations of short-period comets

    NASA Astrophysics Data System (ADS)

    Crovisier, J.; Encrenaz, Th.; Lellouch, E.; Bockelée-Morvan, D.; Altieri, B.; Leech, K.; Salama, A.; Griffin, M. J.; de Graauw, Th.; van Dishoeck, E. F.; Knacke, R.; Brooke, T. Y.

    1999-03-01

    Two Infrared Space Observatory programmes (guaranteed time and open time) were devoted to high-resolution spectroscopic observations of short-period comets. 22P/Kopff was observed on October-December 1996 with SWS and LWS. Due to the weakness of the object, only the ν3 ro-vibrational lines of water were detected, with SWS. Comet 103P/Hartley 2 was observed close to its perihelion (at 1.04 AU from Sun and 0.82 AU from Earth) on January 1998 with SWS, LWS and CAM. The bands of H2O and CO2 at 2.7 and 4.3 μm are detected, with [CO2]/[H2O] = 10 %. The 2.7 μm band of H2O is observed with a high signal-to-noise ratio with SWS, which permits to evaluate the rotational temperature of water to 16-20 K and its ortho-to-para ratio to ~ 2.7, corresponding to a spin temperature of ~ 35 K. The 5-17 μm spectrum of comet Hartley 2 observed with CAM-CVF shows the 9-12 μm signature of silicates. Silicate emission around 10 μm is present at a level of about 20 % of the continuum, with a peak at 11.3 μm indicative of crystalline silicates. This is the first time crystalline silicates are found in a short-period comet. The ISO observations of the Jupiter-family comet P/Hartley 2, presumably originating from the Edgeworth-Kuiper belt, are compared to those of comet Hale-Bopp which came from the Oort cloud.

  8. Development of a novel 3-month drug releasing risperidone microspheres

    PubMed Central

    Yerragunta, Bhanusree; Jogala, Satheesh; Chinnala, Krishna Mohan; Aukunuru, Jithan

    2015-01-01

    Objective: The purpose of this study was to develop an ideal microsphere formulation of risperidone that would prolong the drug release for 3 months in vivo and avoid the need for co-administration of oral tablets. Materials and Methods: Polycaprolactones (PCL) were used as polymers to prepare microspheres. The research included screening and optimizing of suitable commercial polymers of variable molecular weights: PCL-14000, PCL-45000, PCL-80000 or the blends of these polymers to prepare microspheres with zero-order drug-releasing properties without the lag phase. In the present study, the sustained release risperidone microspheres were prepared by o/w emulsion solvent evaporation technique and the yield was determined. Microspheres were evaluated for their drug content and in vitro drug release. Microspheres prepared using a blend of PCL-45000 and PCL-80000 at a ratio of 1:1 resulted in the release of the drug in a time frame of 90 days, demonstrated zero-order drug release without lag time and burst release. This formulation was considered optimized formulation. Optimized formulation was characterized for solid state of the drug using differential scanning calorimetry, surface morphology using scanning electron microscopy and in vivo drug release in rats. Results: The surface of the optimized formulation was smooth, and the drug changed its physical form in the presence of blends of polymers and upon fabrication of microspheres. The optimized formulation also released the drug in vivo for a period of 90 days. Conclusions: From our study, it was concluded that these optimized microspheres showed great potential for a better depot preparation than the marketed Risperdal Consta™ and, therefore, could further improve patient compliance. PMID:25709335

  9. 313 new asteroid rotation periods from Palomar Transient Factory observations

    SciTech Connect

    Chang, Chan-Kao; Ip, Wing-Huen; Lin, Hsing-Wen; Cheng, Yu-Chi; Ngeow, Chow-Choong; Yang, Ting-Chang; Waszczak, Adam; Kulkarni, Shrinivas R.; Levitan, David; Sesar, Branimir; Prince, Thomas A.; Laher, Russ; Surace, Jason

    2014-06-10

    A new asteroid rotation period survey has been carried out by using the Palomar Transient Factory (PTF). Twelve consecutive PTF fields, which covered an area of 87 deg{sup 2} in the ecliptic plane, were observed in the R band with a cadence of ∼20 minutes during 2013 February 15-18. We detected 2500 known asteroids with a diameter range of 0.5 km ≤D ≤ 200 km. Of these, 313 objects had highly reliable rotation periods and exhibited the 'spin barrier' at ∼2 hr. In contrast to the flat spin-rate distribution of the asteroids with 3 km ≤D ≤ 15 km shown by Pravec et al., our results deviated somewhat from a Maxwellian distribution and showed a decrease at the spin rate greater than 5 rev day{sup –1}. One superfast rotator candidate and two possible binary asteroids were also found in this work.

  10. Renal nephroblastoma in a 3-month-old golden retriever.

    PubMed

    Montinaro, Vincenzo; Boston, Sarah E; Stevens, Brian

    2013-07-01

    Nephrectomy was performed in a 3-month-old intact female golden retriever dog for a renal nephroblastoma. The dog has remained disease-free for 19 months with nephrectomy alone. The adoption of human Wilms' tumor grading criteria may be useful in determining clinical stage, adjuvant treatment options, and prognosis in this rare disease.

  11. Emotional and Social Development: Birth to 3 Months

    MedlinePlus

    ... Share Emotional and Social Development: Birth to 3 Months Page Content Article Body By the second month, your baby will spend much of each day ... he can smile, too. Even during his first month, he’ll experiment with primitive grins and grimaces. ...

  12. Renal nephroblastoma in a 3-month-old golden retriever

    PubMed Central

    Montinaro, Vincenzo; Boston, Sarah E.; Stevens, Brian

    2013-01-01

    Nephrectomy was performed in a 3-month-old intact female golden retriever dog for a renal nephroblastoma. The dog has remained disease-free for 19 months with nephrectomy alone. The adoption of human Wilms’ tumor grading criteria may be useful in determining clinical stage, adjuvant treatment options, and prognosis in this rare disease. PMID:24155463

  13. Fractured condyle in a 3-month-old infant.

    PubMed

    Cambell, R L; Moore, R F

    1975-07-01

    A 3-month-old infant sustained trauma to the mandibular symphysis resulting in radiographic evidence of a fracture of the right condylar head. This presented the diffculty of performing a clinical examination and total reliance on history of a trauma and subsequent swelling. Multiple radiographs of the condyles were used to establish the diagnosis and rule out a film artifact. No definitive treatment was required other than muscle exercises and parental instruction as to potential problems.

  14. The observed periods of AP and BP stars

    NASA Astrophysics Data System (ADS)

    Catalano, F. A.; Renson, P.

    1998-02-01

    A catalogue of all the periods up to now proposed for the variations of CP2, CP3, and CP4 stars is presented. The main identifiers (HD and HR), the proper name, the variable-star name, and the spectral type and peculiarity are given for each star as far as the coordinates at 2000.0 and the visual magnitude. The nature of the observed variations (light, spectrum, magnetic field, etc.) is presented in a codified way. The catalogue is arranged in three tables: the bulk of the data, i.e. those referring to CP2, CP3, and CP4 stars, are given in Table 1, while the data concerning He-strong stars are given in Table 2 and those for eclipsing or ellipsoidal variables are collected in Table 3. Notes are also provided at the end of each table, mainly about duplicities. The catalogue contains data on 364 CP stars and is updated to 1996, October 31. This research has made use of the SIMBAD database, operated at CDS, Strasbourg, France.

  15. Patient-reported outcomes 3 months after spine surgery: is it an accurate predictor of 12-month outcome in real-world registry platforms?

    PubMed

    Parker, Scott L; Asher, Anthony L; Godil, Saniya S; Devin, Clinton J; McGirt, Matthew J

    2015-12-01

    OBJECT The health care landscape is rapidly shifting to incentivize quality of care rather than quantity of care. Quality and outcomes registry platforms lie at the center of all emerging evidence-driven reform models and will be used to inform decision makers in health care delivery. Obtaining real-world registry outcomes data from patients 12 months after spine surgery remains a challenge. The authors set out to determine whether 3-month patient-reported outcomes accurately predict 12-month outcomes and, hence, whether 3-month measurement systems suffice to identify effective versus noneffective spine care. METHODS All patients undergoing lumbar spine surgery for degenerative disease at a single medical institution over a 2-year period were enrolled in a prospective longitudinal registry. Patient-reported outcome instruments (numeric rating scale [NRS], Oswestry Disability Index [ODI], 12-Item Short Form Health Survey [SF-12], EQ-5D, and the Zung Self-Rating Depression Scale) were recorded prospectively at baseline and at 3 months and 12 months after surgery. Linear regression was performed to determine the independent association of 3- and 12-month outcome. Receiver operating characteristic (ROC) curve analysis was performed to determine whether improvement in general health state (EQ-5D) and disability (ODI) at 3 months accurately predicted improvement and achievement of minimum clinical important difference (MCID) at 12 months. RESULTS A total of 593 patients undergoing elective lumbar surgery were included in the study. There was a significant correlation between 3-month and 12-month EQ-5D (r = 0.71; p < 0.0001) and ODI (r = 0.70; p < 0.0001); however, the authors observed a sizable discrepancy in achievement of a clinically significant improvement (MCID) threshold at 3 versus 12 months on an individual patient level. For postoperative disability (ODI), 11.5% of patients who achieved an MCID threshold at 3 months dropped below this threshold at 12 months; 10

  16. Dynamic Metabolic Changes during the First 3 Months after 90Y-Ibritumomab Tiuxetan Radioimmunotherapy

    PubMed Central

    Koyama, Keitaro; Kurokawa, Mineo; Ohtomo, Kuni

    2014-01-01

    Objective. To elucidate the time course of tumor metabolism during the first 3 months after 90Y-ibritumomab tiuxetan radioimmunotherapy (RIT) in patients with refractory malignant lymphoma. Materials and Methods. Seven patients with recurrent follicular lymphoma underwent FDG-PET imaging before and after 1-, 4-, and 12-week RIT with 90Y-ibritumomab tiuxetan. Tumor metabolic activity on FDG-PET scans was assessed as the maximum standard uptake value (SUVmax). Results. Decrease in metabolism was detected 1 week after RIT. In the most decreased lesion, SUVmax decreased to 20% of the baseline value during the first week. Most lesions continued to decrease for up to 4 weeks. Some lesions showed increased metabolism from 4 to 12 weeks, while the level of FDG accumulations at 12 weeks was still lower than the baseline. Conclusions. Tumor response to RIT could be observed as early as 1 week after the administration of RIT. After tumor activity decreases, the metabolism may increase at least between 4 and 12 weeks. It suggests that the metabolic changes should be carefully evaluated during this period. PMID:25050390

  17. Comparative energetics of the observed and simulated global circulation during the special observing periods of FGGE

    NASA Technical Reports Server (NTRS)

    Kung, E. C.; Baker, W. E.

    1986-01-01

    Energetics of the observed and simulated global circulation are evaluated in the zonal spectral domain for the special observing periods of FGGE. The study utilizes GLA analyses of FGGE observational data and parallel simulation experiments. There are noticeable differences in energy transformations between the observation and simulation during SOP-1. These include the baroclinic conversion C(n) by the zonal mean motion and short-wave disturbances, and the nonlinear wave-wave interaction L(n) at the long and short waves. The energy transformations of the short-wave disturbances are much more intense in the simulated circulation than in the observation. However, good agreement is noted in the conversion and dissipation of kinetic energy in the large- and cyclone-wave range n = 1-10. Spectral distributions of global energy transformations at the long- and cyclone-wave range indicate that the SOP-2 simulation agrees more closely with the observed fields than the SOP-1 simulation. Other pertinent points of energetics diagnosis are also included in the discussion.

  18. Observations on the cortical silent period in Parkinson's disease.

    PubMed

    Van Der Werf, Y D; Berendse, H W; van Someren, E J W; Stoffers, D; Stam, C J; Wolters, E Ch

    2007-01-01

    Transcranial magnetic stimulation is a tool in the neurosciences to study motor functions and nervous disorders, amongst others. Single pulses of TMS applied over the primary motor cortex lead to a so-called cortical silent period in the recording from the corresponding muscle, i.e. a period of approximately 100ms with no muscle activity. We here show that in Parkinson's disease (PD), this cortical silent period in some cases is interrupted by short bursts of EMG activity. We describe in detail these interruptions in two patients with PD. These interruptions may number up to 3 per cortical silent period and show a consistent frequency across trials and hemispheres within a given patient; the two patients described here do differ, however, in the time-delay of the interruptions and hence the induced frequency. For one patient, the frequency of the interruptions proved to be around 13 Hz, the other patient showed a frequency of around 17 Hz. The results corroborate earlier findings of cortical oscillations elicited by pulses of TMS and may be related to abnormal oscillatory activity found in the cortical-subcortical motor system in PD.

  19. [Tuberculosis in infants less than 3 months of age].

    PubMed

    Del Rosal Rabes, Teresa; Baquero-Artigao, Fernando; Méndez-Echevarría, Ana María; Mellado Peña, María José

    2015-04-29

    A review was conducted on infants less than 3 months of age diagnosed with tuberculosis between 1978 and 2014. Eight patients were diagnosed (1.4% of paediatric tuberculosis cases): 3 confirmed congenital tuberculosis, 3 suspected (endometrial biopsy was not performed), and 2 postnatal tuberculosis. Tuberculin skin test was negative in two patients. Diagnostic performance of culture (7/7, 100%) and PCR (3/3, 100%) of gastric aspirates was higher than that of acid-fast bacilli smears (5/8, 62%) and IGRA test (1/3, 33%). Three patients developed miliary disease, and one died. In conclusion, tuberculosis in this age group is rare, severe, and difficult to diagnose. In cases lacking known postnatal contacts, maternal genital tuberculosis should be ruled out by endometrial biopsy.

  20. Large-Scale periodic solar velocities: An observational study

    NASA Technical Reports Server (NTRS)

    Dittmer, P. H.

    1977-01-01

    Observations of large-scale solar velocities were made using the mean field telescope and Babcock magnetograph of the Stanford Solar Observatory. Observations were made in the magnetically insensitive ion line at 5124 A, with light from the center (limb) of the disk right (left) circularly polarized, so that the magnetograph measures the difference in wavelength between center and limb. Computer calculations are made of the wavelength difference produced by global pulsations for spherical harmonics up to second order and of the signal produced by displacing the solar image relative to polarizing optics or diffraction grating.

  1. Comparison of CAIRS and STATUS Information Storage and Retrieval Software over a 3-Month Period.

    ERIC Educational Resources Information Center

    Hoey, P. O'N.

    1982-01-01

    The Ministry of Agriculture, Fisheries and Food conducted an operational evaluation of the software packages CAIRS and STATUS, which were used to build databases and databanks. Setting up the trial, types of data involved (chemical products used as pesticides), searching and presentation of data, and the final choice are covered. (EJS)

  2. Observation of a Short Period Quasi-periodic Pulsation in Solar X-Ray, Microwave, and EUV Emissions

    NASA Astrophysics Data System (ADS)

    Kumar, Pankaj; Nakariakov, Valery M.; Cho, Kyung-Suk

    2017-02-01

    This paper presents the multiwavelength analysis of a 13 s quasi-periodic pulsation (QPP) observed in hard X-ray (12–300 keV) and microwave (4.9–34 GHz) emissions during a C-class flare that occurred on 2015 September 21. Atmospheric Image Assembly (AIA) 304 and 171 Å images show an emerging loop/flux tube (L1) moving radially outward, which interacts with the preexisting structures within the active region (AR). The QPP was observed during the expansion of and rising motion of L1. The Nobeyama Radioheliograph microwave images in 17/34 GHz channels reveal a single radio source that was co-spatial with a neighboring loop (L2). In addition, using AIA 304 Å images, we detected intensity oscillations in the legs of L2 with a period of about 26 s. A similar oscillation period was observed in the GOES soft X-ray flux derivative. This oscillation period seems to increase with time. We suggest that the observed QPP is most likely generated by the interaction between L2 and L3 observed in the AIA hot channels (131 and 94 Å). The merging speed of loops L2 and L3 was ∼35 km s‑1. L1 was destroyed possibly by its interaction with preexisting structures in the AR, and produced a cool jet with the speed of ∼106–118 km s‑1 associated with a narrow CME (∼770 km s‑1). Another mechanism of the QPP in terms of a sausage oscillation of the loop (L2) is also possible.

  3. Periodization

    PubMed Central

    Lorenz, Daniel S.; Reiman, Michael P.; Walker, John C.

    2010-01-01

    Background: Clinicians are constantly faced with the challenge of designing training programs for injured and noninjured athletes that maximize healing and optimize performance. Periodization is a concept of systematic progression—that is, resistance training programs that follow predictable patterns of change in training variables. The strength training literature is abundant with studies comparing periodization schemes on uninjured, trained, and untrained athletes. The rehabilitation literature, however, is scarce with information about how to optimally design resistance training programs based on periodization principles for injured athletes. The purpose of this review is to discuss relevant training variables and methods of periodization, as well as periodization program outcomes. A secondary purpose is to provide an anecdotal framework regarding implementation of periodization principles into rehabilitation programs. Evidence Acquisition: A Medline search from 1979 to 2009 was implemented with the keywords periodization, strength training, rehabilitation, endurance, power, hypertrophy, and resistance training with the Boolean term AND in all possible combinations in the English language. Each author also undertook independent hand searching of article references used in this review. Results: Based on the studies researched, periodized strength training regimens demonstrate improved outcomes as compared to nonperiodized programs. Conclusions: Despite the evidence in the strength training literature supporting periodization programs, there is a considerable lack of data in the rehabilitation literature about program design and successful implementation of periodization into rehabilitation programs. PMID:23015982

  4. Validation of a 6-hour observation period for cocaine body stuffers

    PubMed Central

    Moreira, Maria; Buchanan, Jennie; Heard, Kennon

    2010-01-01

    Often, patients are brought in to the emergency room after ingesting large amounts of cocaine in an attempt to conceal it. This act is known as “body stuffing.” The observation period required to recognize potential toxic side effects in these patients is not well described in the literature. We sought to validate a treatment algorithm for asymptomatic cocaine body stuffers utilizing a 6-hour observation period by observing the clinical course of cocaine body stuffers over a 24-hour period. A retrospective chart review was performed on all patients evaluated for witnessed or suspected stuffing over two years utilizing a standardized protocol. 106 patients met final inclusion criteria as adult cocaine stuffers. No patients developed life-threatening symptoms and no patients died during observation. In our medical setting, stuffers could be discharged after a 6- hour observation period if there was either complete resolution or absence of clinical symptoms. PMID:20825819

  5. Quasi-periodic pulsations with varying period in multi-wavelength observations of an X-class flare

    SciTech Connect

    Huang, Jing; Tan, Baolin; Zhang, Yin; Karlický, Marian; Mészárosová, Hana

    2014-08-10

    This work presents an interesting phenomenon of the period variation in quasi-periodic pulsations (QPPs) observed during the impulsive phase of a coronal mass ejection-related X1.1 class flare on 2012 July 6. The period of QPPs was changed from 21 s at soft X-rays (SXR) to 22-23 s at microwaves, to ∼24 s at extreme ultraviolet emissions (EUV), and to 27-32 s at metric-decimetric waves. The microwave, EUV, and SXR QPPs, emitted from flare loops of different heights, were oscillating in phase. Fast kink mode oscillations were proposed to be the modulation mechanism, which may exist in a wide region in the solar atmosphere from the chromosphere to the upper corona or even to the interplanetary space. Changed parameters of flare loops through the solar atmosphere could result in the varying period of QPPs at different wavelengths. The first appearing microwave QPPs and quasi-periodic metric-decimetric type III bursts were generated by energetic electrons. This may imply that particle acceleration or magnetic reconnection were located between these two non-thermal emission sources. Thermal QPPs (in SXR and EUV emissions) occurred later than the nonthermal ones, which would suggest a some time for plasma heating or energy dissipation in flare loops during burst processes. At the beginning of flare, a sudden collapse and expansion of two separated flare loop structures occurred simultaneously with the multi-wavelength QPPs. An implosion in the corona, including both collapse and expansion of flare loops, could be a trigger of loop oscillations in a very large region in the solar atmosphere.

  6. Coping Card Usage can Further Reduce Suicide Reattempt in Suicide Attempter Case Management Within 3-Month Intervention.

    PubMed

    Wang, Ying-Chuan; Hsieh, Ling-Yu; Wang, Ming-Yu; Chou, Cheng-Hsiang; Huang, Min-Wei; Ko, Huei-Chen

    2016-02-01

    This randomized controlled trial was designed to evaluate the effectiveness of using crisis coping cards (n = 32) in the case management of suicide prevention compared with case management without the use of coping cards (n = 32) over a 3-month intervention period. The generalized estimating equation was used to examine the interaction effect between treatments and time on suicide risk, depression, anxiety, and hopelessness. Results indicated that subsequent suicidal behaviors, severity of suicide risk, depression, anxiety, and hopelessness were reduced more in the coping card intervention group compared to the case management only group. Moreover, for the survival curves of time to suicide reattempt, the coping card group showed a significantly longer time to reattempt than the case management only group at 2-month and 3-month intervention periods.

  7. Archive of observations of periodic comet Crommelin made during its 1983-84 apparition

    NASA Technical Reports Server (NTRS)

    Sekanina, Z. (Editor); Aronsson, M.

    1985-01-01

    This is an archive of 680 reduced observations of Periodic Comet Crommelin made during its 1984 apparition. The archive integrates reports by members of the eight networks of the International Halley Watch (IHW) and presents the results of a trial run designed to test the preparedness of the IHW organization for the current apparition of Periodic Comet Halley.

  8. Intestinal calcium-binding protein 3 months after massive small bowel resection in the piglet.

    PubMed

    Margolis, A; Ricour, C; Harouchi, A; Guyot, M; Laouari, D; Balsan, S

    1977-12-01

    Changes in intestinal calcium-binding protein and calcium binding activity were studied at resection and 3 months after 90% small bowel resection in piglets and one adult pig. A calcium-binding protein (MW congruent to 11.000) with calcium-dependent eletrophoretic mobility was partially purified from mucosal extract of proximal jejunum, mid-gut, and ileum. The concentration of calcium-binding protein and the calcium-binding activity of the intact animals were found highest in the proximal jejunal segment, lowest in the ileal segment. After resection in the four surviving animals out of nine, a significant increase in calcium-binding activity was observed in the proximal jejunum and in the distal ileal segment. The change in calcium-binding activity was much more marked in the ileum than the jejunum. These data demonstrate that pig intestinal mucosa possesses an adaptive capacity to increase the synthesis of calcium-binding protein after massive small bowel resection.

  9. Torsional oscillations and observed rotational period variations in early-type stars

    NASA Astrophysics Data System (ADS)

    Krtička, J.; Mikulášek, Z.; Henry, G. W.; Kurfürst, P.; Karlický, M.

    2017-01-01

    Some chemically peculiar stars in the upper main sequence show rotational period variations of unknown origin. We propose that these variations are a consequence of the propagation of internal waves in magnetic rotating stars that lead to the torsional oscillations of the star. We simulate the magnetohydrodynamic waves and calculate resonant frequencies for two stars that show rotational variations: CU Vir and HD 37776. We provide updated analyses of rotational period variations in these stars and compare our results with numerical models. For CU Vir, the length of the observed rotational period cycle, Π=67.6(5) yr, can be well reproduced by the models, which predict a cycle length of 51 yr. However, for HD 37776, the observed lower limit of the cycle length, Π ≥ 100 yr, is significantly longer than the numerical models predict. We conclude that torsional oscillations provide a reasonable explanation at least for the observed period variations in CU Vir.

  10. Observations and Light Curve Solutions of Four Ultrashort-Period Binaries

    NASA Astrophysics Data System (ADS)

    Kjurkchieva, D.; Popov, V.; Vasileva, D.; Petrov, N.

    2016-06-01

    The paper presents light curve solutions of our observations of four new ultrashort-period eclipsing binaries with MS components. Two of them have periods almost at the upper limit (0.22 days) of the ultrashort-period binaries, while the periods of around 0.18 days of CSS J171508.5+350658 and CSS J214633.8+120016 are amongst the shortest known orbital periods. CSS J171410.0+445850, CSS J214633.8+120016 and CSS J224326.0+154532 are overcontact binaries with fillout factors around 0.25 while CSS J171508.5+350658 is a semidetached system. The two targets with shortest periods consist of M dwarfs.

  11. The Trend in the Observation of Legacy Long Period Variable Stars (Poster abstract)

    NASA Astrophysics Data System (ADS)

    Dudley, R.

    2015-06-01

    (Abstract only) A decrease in the number of observers of the Legacy Long Period Variable Stars has been noted by the AAVSO. Amongst the observing community there is the perception that observers collecting digital data is making up for this gap. Data from the annual President's report (2002-2013) and the AAVSO International Data Base for the years 1993, 2003, and 2013 were analyzed. For the period of 2002 to 2013 the total number of observers remained fairly constant (816 ± 97) with a large bump in 2011. The number of observations has slowly declined since 2007 though there has recently been an increase in the number of observations. From the AID data the number of observations reached a maximum in 2003 and has slowly declined afterwards. These trends as well as other information gleamed from the data will be present and discussed.

  12. Cortisol reactivity, maternal sensitivity, and learning in 3-month-old infants.

    PubMed

    Thompson, Laura A; Trevathan, Wenda R

    2008-01-01

    This study investigated the effects of adrenocortical functioning on infant learning during an emotionally challenging event (brief separation from mother). We also explored possible relationships between maternal sensitivity and both infant and maternal cortisol reactivity during the learning/maternal separation episode. Sixty-three 3-month-olds and their mothers were videotaped for a 10 min normal interaction period, and mother-infant behavioral synchrony was measured using Isabella and Belsky's [Isabella, R. A., & Belsky, J. (1991). Interactional synchrony and the origins of infant-mother attachment: A replication study. Child Development, 62, 373-384] coding scheme. The percentage of synchronous behaviors served as a measure of maternal sensitivity. Learning and short-term memory involved relating the infant's mother's voice with a moving colored block in a preferential looking paradigm. Infants whose cortisol increased during the session showed no learning or memory, infants whose cortisol declined appeared to learn and remember the association, while infants whose cortisol did not change evidenced learning, but not memory for the voice/object correspondence. Sensitivity and cortisol reactivity were correlated for mothers, but not for infants. Infant and maternal cortisol values for the first sampling period were highly correlated, but their cortisol reactivity values were uncorrelated, supporting the notion that infants and mothers have coordinated adrenocortical functioning systems when physically together, but become uncoordinated during a separation/learning event.

  13. Prediction of glycated hemoglobin levels at 3 months after metabolic surgery based on the 7-day plasma metabolic profile.

    PubMed

    Kwon, Hyuk Nam; Lee, Yeon Ji; Kang, Ju-Hee; Choi, Ji-Ho; An, Yong Jin; Kang, Sunmi; Lee, Dae Hyun; Suh, Young Ju; Heo, Yoonseok; Park, Sunghyouk

    2014-01-01

    Metabolic surgery has been shown to provide better glycemic control for type 2 diabetes than conventional therapies. Still, the outcomes of the surgery are variable, and prognostic markers reflecting the metabolic changes by the surgery are yet to be established. NMR-based plasma metabolomics followed by multivariate regression was used to test the correlation between the metabolomic profile at 7-days after surgery and glycated hemoglobin (HbA1c) levels at 3-months (and up to 12 months with less patients), and to identify the relevant markers. Metabolomic profiles at 7-days could differentiate the patients according to the HbA1c improvement status at 3-months. The HbA1c values were predicted based on the metabolomics profile with partial least square regression, and found to be correlated with the observed values. Metabolite analysis suggested that 3-Hydroxybutyrate (3-HB) and glucose contributes to this prediction, and the [3-HB]/[glucose] exhibited a modest to good correlation with the HbA1c level at 3-months. The prediction of 3-month HbA1c using 7-day metabolomic profile and the suggested new criterion [3-HB]/[glucose] could augment current prognostic modalities and help clinicians decide if drug therapy is necessary.

  14. Solar wind plasma periodicities observed at 1 AU by IMP 8

    NASA Technical Reports Server (NTRS)

    Paularena, K. I.; Szabo, A.; Lazarus, A. J.

    1995-01-01

    The IMP 8 spacecraft has been in Earth orbit since 1973, gathering plasma data over one complete 22-year solar cycle. These data are being examined to look for periodicities at time scales ranging from several hours to the entire span of the data set. A 1.3-year periodicity in the radial speed observed by IMP 8 and Voyager 2 has already been reported for the years from 1987 to 1993. The periodogram method, useful for unevenly sampled data such as the IMP 8 plasma data, has been used to search for other periods. It is interesting to note that the 13-year period is not present in the out-of-the-ecliptic component of the velocity (Vz), although a 1-year period is very obvious both visually and on the periodogram. Both components show a very strong peak associated with the 11-year solar cycle variation. This work will be extended to the thermal speed (a measure of the wind's temperature) and density, although the frequent correlations between these parameters and the velocity are expected to cause similar results. Additionally, the fine resolution data will be examined for shorter time periods than are visible using the hourly average data which are appropriate for longer periods. A comparison with periods observed at other spacecraft may also be made.

  15. Estimating the Period and Q of the Chandler Wobble from Observations and Models of its Excitation

    NASA Astrophysics Data System (ADS)

    Gross, R. S.; Nastula, J.

    2012-12-01

    Any irregularly shaped solid body rotating about some axis that is not aligned with its figure axis will freely wobble as it rotates. For the Earth, this free wobble is known as the Chandler wobble in honor of S. C. Chandler, Jr. who first observed it in 1891. Unlike the forced wobbles of the Earth, such as the annual wobble, whose periods are the same as the periods of the forcing mechanisms, the period of the free Chandler wobble is a function of the internal structure and rheology of the Earth, and its decay time constant, or quality factor Q, is a function of the dissipation mechanism(s), like mantle anelasticity, that are acting to dampen it. Improved estimates of the period and Q of the Chandler wobble can therefore be used to improve our understanding of these properties of the Earth. Here, estimates of the period and Q of the Chandler wobble are obtained by finding those values that minimize the power within the Chandler band of the difference between observed and modeled polar motion excitation spanning 1962-2010. Atmosphere, ocean, and hydrology models are used to model the excitation caused by both mass and motion variations within these global geophysical fluids. Direct observations of the excitation caused by mass variations as determined from GRACE time varying gravitational field measurements are also used. The resulting estimates of the period and Q of the Chandler wobble will be presented along with a discussion of the robustness of the estimates.

  16. Estimating the Period and Q of the Chandler Wobble from Observations and Models of its Excitation

    NASA Astrophysics Data System (ADS)

    Gross, R. S.; Nastula, J.

    2014-12-01

    Any irregularly shaped solid body rotating about some axis that is not aligned with its figure axis will freely wobble as it rotates. For the Earth, this free wobble is known as the Chandler wobble in honor of S. C. Chandler, Jr. who first observed it in 1891. Unlike the forced wobbles of the Earth, such as the annual wobble, whose periods are the same as the periods of the forcing mechanisms, the period of the free Chandler wobble is a function of the internal structure and rheology of the Earth, and its decay time constant, or quality factor Q, is a function of the dissipation mechanism(s), like mantle anelasticity, that are acting to dampen it. Improved estimates of the period and Q of the Chandler wobble can therefore be used to improve our understanding of these properties of the Earth. Here, estimates of the period and Q of the Chandler wobble are obtained by finding those values that minimize the power within the Chandler band of the difference between observed and modeled polar motion excitation spanning 1962-2010. Atmosphere, ocean, and hydrology models are used to model the excitation caused by both mass and motion variations within these global geophysical fluids. Direct observations of the excitation caused by mass variations as determined from GRACE time varying gravitational field measurements are also used. The resulting estimates of the period and Q of the Chandler wobble will be presented along with a discussion of the robustness of the estimates.

  17. Plasticity of visual attention in Isha yoga meditation practitioners before and after a 3-month retreat.

    PubMed

    Braboszcz, Claire; Cahn, B Rael; Balakrishnan, Bhavani; Maturi, Raj K; Grandchamp, Romain; Delorme, Arnaud

    2013-01-01

    Meditation has lately received considerable interest from cognitive neuroscience. Studies suggest that daily meditation leads to long lasting attentional and neuronal plasticity. We present changes related to the attentional systems before and after a 3 month intensive meditation retreat. We used three behavioral psychophysical tests - a Stroop task, an attentional blink task, and a global-local letter task-to assess the effect of Isha yoga meditation on attentional resource allocation. 82 Isha yoga practitioners were tested at the beginning and at the end of the retreat. Our results showed an increase in correct responses specific to incongruent stimuli in the Stroop task. Congruently, a positive correlation between previous meditation experience and accuracy to incongruent Stroop stimuli was also observed at baseline. We also observed a reduction of the attentional blink. Unexpectedly, a negative correlation between previous meditation experience and attentional blink performance at baseline was observed. Regarding spatial attention orientation as assessed using the global-local letter task, participants showed a bias toward local processing. Only slight differences in performance were found pre- vs. post- meditation retreat. Biasing toward the local stimuli in the global-local task and negative correlation of previous meditation experience with attentional blink performance is consistent with Isha practices being focused-attention practices. Given the relatively small effect sizes and the absence of a control group, our results do not allow clear support nor rejection of the hypothesis of meditation-driven neuronal plasticity in the attentional system for Isha yoga practice.

  18. Examining Periodic Solar-Wind Density Structures Observed in the SECCHI Heliospheric Imagers

    NASA Technical Reports Server (NTRS)

    Viall, Nicholeen M.; Spence, Harlan E.; Vourlidas, Angelos; Howard, Russell

    2010-01-01

    We present an analysis of small-scale, periodic, solar-wind density enhancements (length scales as small as approximately equals 1000 Mm) observed in images from the Heliospheric Imager (HI) aboard STEREO-A. We discuss their possible relationship to periodic fluctuations of the proton density that have been identified at 1 AU using in-situ plasma measurements. Specifically, Viall, Kepko, and Spence examined 11 years of in-situ solar-wind density measurements at 1 AU and demonstrated that not only turbulent structures, but also nonturbulent, periodic density structures exist in the solar wind with scale sizes of hundreds to one thousand Mm. In a subsequent paper, Viall, Spence, and Kasper analyzed the alpha-to-proton solar-wind abundance ratio measured during one such event of periodic density structures, demonstrating that the plasma behavior was highly suggestive that either temporally or spatially varying coronal source plasma created those density structures. Large periodic density structures observed at 1 AU, which were generated in the corona, can be observable in coronal and heliospheric white-light images if they possess sufficiently high density contrast. Indeed, we identify such periodic density structures as they enter the HI field of view and follow them as they advect with the solar wind through the images. The smaller, periodic density structures that we identify in the images are comparable in size to the larger structures analyzed in-situ at 1 AU, yielding further evidence that periodic density enhancements are a consequence of coronal activity as the solar wind is formed.

  19. Esthetic restorations: observations and insights gained over a 5-year period demonstrated with three case reports.

    PubMed

    Obama, Tadakazu

    2007-01-01

    This article presents two prosthodontically treated patient cases that were observed over a period of at least 5 years after treatment. The evaluation, diagnosis, treatment planning, and treatment stages were critically reviewed and reassessed from different perspectives. The conclusions drawn from this evaluation were subsequently implemented in a third clinical case. To ensure the long-term success of a restoration, certain biologic and mechanical principles must be observed, and the appropriate prosthodontic treatment must be chosen accordingly.

  20. First observations of W Virginis stars with K2: detection of period doubling

    NASA Astrophysics Data System (ADS)

    Plachy, E.; Molnár, L.; Jurkovic, M. I.; Smolec, R.; Moskalik, P. A.; Pál, A.; Szabados, L.; Szabó, R.

    2017-02-01

    We present the first analysis of W Vir stars observed by the Kepler space telescope in the K2 mission. Clear cycle-to-cycle variations were detected in the light curves of KT Sco and the globular cluster member M80-V1. While the variations in the former star seem to be irregular on the short time-scale of the K2 data, the latter appears to experience period doubling in its pulsation. Ground-based colour data confirmed that both stars are W Vir-type pulsators, while a comparison with historical photometric time series data revealed drastic period changes in both stars. For comparison we reexamine ground-based observations of W Vir, the prototype of the class, and conclude that it shows period doubling instead of mode beating. These results support the notion that non-linear dynamics plays an important role in the pulsation of W Virginis-type stars.

  1. LOW-FREQUENCY OBSERVATIONS OF TRANSIENT QUASI-PERIODIC RADIO EMISSION FROM THE SOLAR ATMOSPHERE

    SciTech Connect

    Sasikumar Raja, K.; Ramesh, R.

    2013-09-20

    We report low-frequency observations of quasi-periodic, circularly polarized, harmonic type III radio bursts whose associated sunspot active regions were located close to the solar limb. The measured periodicity of the bursts at 80 MHz was ≈5.2 s, and their average degree of circular polarization (dcp) was ≈0.12. We calculated the associated magnetic field B (1) using the empirical relationship between the dcp and B for the harmonic type III emission, and (2) from the observed quasi-periodicity of the bursts. Both the methods result in B ≈ 4.2 G at the location of the 80 MHz plasma level (radial distance r ≈ 1.3 R{sub ☉}) in the active region corona.

  2. Spurious One-Month and One-Year Periods in Visual Observations of Variable Stars

    NASA Astrophysics Data System (ADS)

    Percy, J. R.

    2015-12-01

    Visual observations of variable stars, when time-series analyzed with some algorithms such as DC-DFT in vstar, show spurious periods at or close to one synodic month (29.5306 days), and also at about a year, with an amplitude of typically a few hundredths of a magnitude. The one-year periods have been attributed to the Ceraski effect, which was believed to be a physiological effect of the visual observing process. This paper reports on time-series analysis, using DC-DFT in vstar, of visual observations (and in some cases, V observations) of a large number of stars in the AAVSO International Database, initially to investigate the one-month periods. The results suggest that both the one-month and one-year periods are actually due to aliasing of the stars' very low-frequency variations, though they do not rule out very low-amplitude signals (typically 0.01 to 0.02 magnitude) which may be due to a different process, such as a physiological one. Most or all of these aliasing effects may be avoided by using a different algorithm, which takes explicit account of the window function of the data, and/or by being fully aware of the possible presence of and aliasing by very low-frequency variations.

  3. Periodic waves in the lower thermosphere observed by OI630 nm airglow images

    NASA Astrophysics Data System (ADS)

    Paulino, I.; Medeiros, A. F.; Vadas, S. L.; Wrasse, C. M.; Takahashi, H.; Buriti, R. A.; Leite, D.; Filgueira, S.; Bageston, J. V.; Sobral, J. H. A.; Gobbi, D.

    2016-02-01

    Periodic wave structures in the thermosphere have been observed at São João do Cariri (geographic coordinates: 36.5° W, 7.4° S; geomagnetic coordinates based on IGRF model to 2015: 35.8° E, 0.48° N) from September 2000 to November 2010 using OI630.0 nm airglow images. During this period, which corresponds to almost one solar cycle, characteristics of 98 waves were studied. Similarities between the characteristics of these events and observations at other places around the world were noted, primarily the spectral parameters. The observed periods were mostly found between 10 and 35 min; horizontal wavelengths ranged from 100 to 200 km, and phase speed from 30 to 180 m s-1. These parameters indicated that some of the waves, presented here, are slightly faster than those observed previously at low and middle latitudes (Indonesia, Carib and Japan), indicating that the characteristics of these waves may change at different places. Most of observed waves have appeared during magnetically quiet nights, and the occurrence of those waves followed the solar activity. Another important characteristic is the quasi-monochromatic periodicity that distinguish them from the single-front medium-scale traveling ionospheric disturbances (MSTIDs) that have been observed previously over the Brazilian region. Moreover, most of the observed waves did not present a phase front parallel to the northeast-southwest direction, which is predicted by the Perkins instability process. It strongly suggests that most of these waves must have had different generation mechanisms from the Perkins instability, which have been pointed out as being a very important mechanism for the generation of MSTIDs in the lower thermosphere.

  4. Effectiveness of MR Angiography for the Primary Diagnosis of Acute Pulmonary Embolism: Clinical Outcomes at 3 Months and 1 Year

    PubMed Central

    Schiebler, Mark L.; Nagle, Scott K.; François, Christopher J.; Repplinger, Michael D.; Hamedani, Azita G.; Vigen, Karl K.; Yarlagadda, Rajkumar; Grist, Thomas M.; Reeder, Scott B.

    2014-01-01

    Purpose To determine the effectiveness of MR angiography for pulmonary embolism (MRA-PE) in symptomatic patients. Materials and Methods We retrospectively reviewed all patients whom were evaluated for possible pulmonary embolism (PE) using MRA-PE. A 3-month and 1-year from MRA-PE electronic medical record (EMR) review was performed. Evidence for venous thromboembolism (VTE) (or death from PE) within the year of follow-up was the outcome surrogate for this study. Results There were 190 MRA-PE exams performed with 97.4% (185/190) of diagnostic quality. There were 148 patients (120 F: 28 M) that had both a diagnostic MRA-PE exam and 1 complete year of EMR follow-up. There were 167 patients (137 F: 30 M) with 3 months or greater follow-up. We found 83% (139/167) and 81% (120/148) MRA-PE exams negative for PE at 3 months and 1 year, respectively. Positive exams for PE were seen in 14% (23/167). During the 1-year follow-up period, five patients (false negative) were diagnosed with DVT (5/148 = 3.4 %), and one of these patients also experienced a non–life-threatening PE. The negative predictive value (NPV) for MRA-PE was 97% (92–99; 95% CI) at 3 months and 96% (90–98; 95% CI) with 1 year of follow-up. Conclusion The NPV of MRA-PE, when used for the primary diagnosis of pulmonary embolism in symptomatic patients, were found to be similar to the published values for CTA-PE. In addition, the technical success rate and safety of MRA-PE were excellent. PMID:23553735

  5. Jointly structuring triadic spaces of meaning and action: book sharing from 3 months on

    PubMed Central

    Rossmanith, Nicole; Costall, Alan; Reichelt, Andreas F.; López, Beatriz; Reddy, Vasudevi

    2014-01-01

    This study explores the emergence of triadic interactions through the example of book sharing. As part of a naturalistic study, 10 infants were visited in their homes from 3–12 months. We report that (1) book sharing as a form of infant-caregiver-object interaction occurred from as early as 3 months. Using qualitative video analysis at a micro-level adapting methodologies from conversation and interaction analysis, we demonstrate that caregivers and infants practiced book sharing in a highly co-ordinated way, with caregivers carving out interaction units and shaping actions into action arcs and infants actively participating and co-ordinating their attention between mother and object from the beginning. We also (2) sketch a developmental trajectory of book sharing over the first year and show that the quality and dynamics of book sharing interactions underwent considerable change as the ecological situation was transformed in parallel with the infants' development of attention and motor skills. Social book sharing interactions reached an early peak at 6 months with the infants becoming more active in the coordination of attention between caregiver and book. From 7 to 9 months, the infants shifted their interest largely to solitary object exploration, in parallel with newly emerging postural and object manipulation skills, disrupting the social coordination and the cultural frame of book sharing. In the period from 9 to 12 months, social book interactions resurfaced, as infants began to effectively integrate manual object actions within the socially shared activity. In conclusion, to fully understand the development and qualities of triadic cultural activities such as book sharing, we need to look especially at the hitherto overlooked early period from 4 to 6 months, and investigate how shared spaces of meaning and action are structured together in and through interaction, creating the substrate for continuing cooperation and cultural learning. PMID:25540629

  6. Statistical properties of quasi-periodic pulsations in white-light flares observed with Kepler

    NASA Astrophysics Data System (ADS)

    Pugh, C. E.; Armstrong, D. J.; Nakariakov, V. M.; Broomhall, A.-M.

    2016-07-01

    We embark on a study of quasi-periodic pulsations (QPPs) in the decay phase of white-light stellar flares observed by Kepler. Out of the 1439 flares on 216 different stars detected in the short-cadence data using an automated search, 56 flares are found to have pronounced QPP-like signatures in the light curve, of which 11 have stable decaying oscillations. No correlation is found between the QPP period and the stellar temperature, radius, rotation period and surface gravity, suggesting that the QPPs are independent of global stellar parameters. Hence they are likely to be the result of processes occurring in the local environment. There is also no significant correlation between the QPP period and flare energy, however there is evidence that the period scales with the QPP decay time for the Gaussian damping scenario, but not to a significant degree for the exponentially damped case. This same scaling has been observed for MHD oscillations on the Sun, suggesting that they could be the cause of the QPPs in those flares. Scaling laws of the flare energy are also investigated, supporting previous reports of a strong correlation between the flare energy and stellar temperature/radius. A negative correlation between the flare energy and stellar surface gravity is also found.

  7. Observation of quasi-periodic solar radio bursts associated with propagating fast-mode waves

    NASA Astrophysics Data System (ADS)

    Goddard, C. R.; Nisticò, G.; Nakariakov, V. M.; Zimovets, I. V.; White, S. M.

    2016-10-01

    Aims: Radio emission observations from the Learmonth and Bruny Island radio spectrographs are analysed to determine the nature of a train of discrete, periodic radio "sparks" (finite-bandwidth, short-duration isolated radio features) which precede a type II burst. We analyse extreme ultraviolet (EUV) imaging from SDO/AIA at multiple wavelengths and identify a series of quasi-periodic rapidly-propagating enhancements, which we interpret as a fast wave train, and link these to the detected radio features. Methods: The speeds and positions of the periodic rapidly propagating fast waves and the coronal mass ejection (CME) were recorded using running-difference images and time-distance analysis. From the frequency of the radio sparks the local electron density at the emission location was estimated for each. Using an empirical model for the scaling of density in the corona, the calculated electron density was used to obtain the height above the surface at which the emission occurs, and the propagation velocity of the emission location. Results: The period of the radio sparks, δtr = 1.78 ± 0.04 min, matches the period of the fast wave train observed at 171 Å, δtEUV = 1.7 ± 0.2 min. The inferred speed of the emission location of the radio sparks, 630 km s-1, is comparable to the measured speed of the CME leading edge, 500 km s-1, and the speeds derived from the drifting of the type II lanes. The calculated height of the radio emission (obtained from the density) matches the observed location of the CME leading edge. From the above evidence we propose that the radio sparks are caused by the quasi-periodic fast waves, and the emission is generated as they catch up and interact with the leading edge of the CME. The movie associated to Fig. 2 is available at http://www.aanda.org

  8. Observed changes of temperature extremes in Serbia over the period 1961 - 2010

    NASA Astrophysics Data System (ADS)

    Ruml, Mirjana; Gregorić, Enike; Vujadinović, Mirjam; Radovanović, Slavica; Matović, Gordana; Vuković, Ana; Počuča, Vesna; Stojičić, Djurdja

    2017-01-01

    The analysis of spatiotemporal changes of temperature extremes in Serbia, based on 18 ETCCDI indices, was performed using daily minimum and maximum temperature observations from 26 meteorological stations over the period 1961-2010. The observation period was divided into two sub-periods (1961-1980 and 1981-2010) according to the results of the sequential Mann-Kendall test. Temporal trends were evaluated by a least-squares linear regression method. The average annual minimum temperature displayed a mixed pattern of increasing, decreasing, and no trends over 1961-1980 and a significant increasing trend over 1981-2010 across the whole country, with a regionally averaged rate of 0.48 °C per decade. The average annual maximum temperature showed a decreasing trend during 1961-1980 and a significant increasing trend at all stations during 1981-2010, with a regionally averaged rate of 0.56 °C per decade. Hot indices exhibited a general cooling tendency until 1980 and a warming tendency afterwards, with the most pronounced trends in the number of summer and tropical days during the first period and in the frequency of warm days and nights in the second. Cold indices displayed a mostly warming tendency over the entire period, with the most remarkable increase in the lowest annual maximum temperature and the number of ice days during the first period and in the frequency of cool nights during the second. At most stations, the diurnal temperature range showed a decrease until 1980 and no change or a slight increase afterwards. The lengthening of the growing season was much more pronounced in the later period. The computed correlation coefficient between the annual temperature indices and large-scale circulation features revealed that the East Atlantic pattern displayed much stronger association with examined indices than the North Atlantic Oscillation and East Atlantic/West Russia pattern.

  9. IMAGING AND SPECTRAL OBSERVATIONS OF QUASI-PERIODIC PULSATIONS IN A SOLAR FLARE

    SciTech Connect

    Li, D.; Ning, Z. J.; Zhang, Q. M.

    2015-07-01

    We explore the quasi-periodic pulsations (QPPs) in a solar flare observed by Fermi Gamma-ray Burst Monitor, Solar Dynamics Observatory, Solar Terrestrial Relations Observatory, and Interface Region Imaging Spectrograph (IRIS) on 2014 September 10. QPPs are identified as the regular and periodic peaks on the rapidly varying components, which are the light curves after removing the slowly varying components. The QPPs display only three peaks at the beginning on the hard X-ray emissions, but 10 peaks on the chromospheric and coronal line emissions, and more than seven peaks (each peak corresponds to a type III burst on the dynamic spectra) at the radio emissions. A uniform quasi-period of about 4 minutes is detected among them. AIA imaging observations exhibit that the 4-minute QPPs originate from the flare ribbon and tend to appear on the ribbon front. IRIS spectral observations show that each peak of the QPPs tends to a broad line width and a red Doppler velocity at C i, O iv, Si iv, and Fe xxi lines. Our findings indicate that the QPPs are produced by the non-thermal electrons that are accelerated by the induced quasi-periodic magnetic reconnections in this flare.

  10. Local Scale Radiobrightness Modelling during Intensive Observing Period-4 of the Cold Land Processes Experiment-1

    NASA Technical Reports Server (NTRS)

    Kim, Edward J.; Tedesco, Marco; deRoo, Roger; England, Anthony W.; Gu, Haoyu; Pham, Hanh; Boprie, David; Graf, Tobias; Koike, Toshio; Armstrong, Richard

    2004-01-01

    The NASA Cold Land Processes Field Experiment (CLPX-1) was designed to provide microwave remote sensing observations and ground truth for studies of snow and frozen ground remote sensing, particularly issues related to scaling. CLPX-1 was conducted in the spring of 2003 in Colorado, USA. Initial forward model validation work is concentrating on the Local-Scale Observation Site (LSOS), a 0.8 ha study site consisting of open meadows separated by trees where the most detailed measurements were made of snow depth and temperature, density, and grain size profiles. This paper will focus on the ability of forward Dense Medium Radiative Transfer (DMRT) modelling, combined with snowpack measurements to reproduce the radiobrightness signatures observed by the University of Michigan s Truck-Mounted Radiometer System at 19 and 37 GHz during the 4th Intensive Observing Period (IOP4) in March, 2003. Unlike the earlier IOP3, conditions during IOP4 include both wet and dry periods, providing a valuable test of DMRT model performance. Observations of upwelling and downwelling tree radiobrightness will be used to formulate a simple model for the effect of trees within the field of view. In addition, a comparison will be made for the one day of coincident observations by the University of Tokyo s Ground- Based Microwave Radiometer-7 (GBMR-7). These analyses will help guide the choice of future snow retrieval algorithms and the design of future Cold Lands observing systems.

  11. Observations of long-period Cepheids between l = 294 and 331 deg

    NASA Technical Reports Server (NTRS)

    Grayzeck, E. J.

    1978-01-01

    Photoelectric and spectroscopic observations of long-period Cepheids, as well as 21-cm profiles in the directions of these young stars, are presented for the Crux-Centaurus-Circinus-Norma section of the Milky Way. The UBV data have been used to revise periods and light-curve parameters and ultimately to calculate the distances of these stars. From the spectroscopic information velocity estimates have been made. Finally, the stellar velocities have been compared with H I gas motions detected along the same line of sight. These results are briefly discussed with a view to understanding the spiral structure of the region.

  12. Observation of periodic waves in a pulse-coupled neural network.

    PubMed

    Johnson, J L; Ritter, D

    1993-08-01

    A pulse-coupled neural network was implemented, for the first time to our knowledge, in a hybrid electro-optical laboratory demonstration system. Dynamic coherent traveling-wave patterns were observed that repeated their spatial patterns at each locality with a period that depended on the local input pattern and strength. Coherence and periodicity were maintained far beyond the physical limits of the linking receptive fields, suggesting a new mechanism for information transmission in a network with limited local connectivity. With no linking, the output became chaotic because the relative phases increased linearly in time.

  13. Determination of solar wind elemental abundances from M/Q observations during three periods in 1980

    NASA Astrophysics Data System (ADS)

    Kunz, S.; Bochsler, P.; Geiss, J.; Ogilvie, K. W.; Coplan, M. A.

    1983-10-01

    Mass spectra in the range 2 ≤ M/Q ≤ 3 provided by a high resolution mode of the ISEE-3 Plasma Composition Experiment were evaluated for three selected periods during early 1980. The observed Ne/O ratios are compatible with estimated solar abundance ratios. In two of the three periods, the He/Ne-ratios agree with the Apollo foil results. Freezing-in temperatures for oxygen are similar to those obtained by other groups. Possible reasons for an unexpectedly high flux at M/Q = 2.4 are discussed.

  14. Imaging Observations of Quasi-periodic Pulsations in Solar Flare Loops with SDO/AIA

    NASA Astrophysics Data System (ADS)

    Su, J. T.; Shen, Y. D.; Liu, Y.; Liu, Y.; Mao, X. J.

    2012-08-01

    Quasi-periodic pulsations (QPPs) of flaring emission with periods from a few seconds to tens of minutes have been widely detected from radio bands to γ-ray emissions. However, in the past the spatial information of pulsations could not be utilized well due to the instrument limits. We report here imaging observations of the QPPs in three loop sections during a C1.7 flare with periods of P = 24 s-3 minutes by means of the extreme-ultraviolet 171 Å channel of the Atmospheric Imaging Assembly (AIA) instrument on board the Solar Dynamics Observatory. We confirm that the QPPs with the shortest period of 24 s were not of an artifact produced by the Nyquist frequency of the AIA 12 s cadence. The QPPs in the three loop sections were interconnected and closely associated with the flare. The detected perturbations propagated along the loops at speeds of 65-200 km s-1, close to those of acoustic waves in them. The loops were made up of many bright blobs arranged in alternating bright and dark changes in intensity (spatial periodical distribution) with the wavelengths 2.4-5 Mm (as if they were magnetohydrodynamic waves). Furthermore, in the time-distance diagrams, the detected perturbation wavelengths of the QPPs are estimated to be ~10 Mm, which evidently do not fit the above ones of the spatial periodic distributions and produce a difference of a factor of 2-4 with them. It is suggested that the short QPPs with periods P < 60 s were possibly sausage-mode oscillations and the long QPPs with periods P > 60 s were the higher (e.g., >2nd) harmonics of slow magnetoacoustic waves.

  15. Simultaneous observation of whistlers and emissions during a geomagnetically quiet period at low latitude

    NASA Astrophysics Data System (ADS)

    Singh, Ashutosh K.; Singh, K. K.; Singh, A. K.; Lalmani

    2011-02-01

    A unique night-time natural electromagnetic disturbances in the VLF/ELF range received during a magnetically quite period at a low latitude Indian ground station, Jammu (geomag. lat. 19°26' N, L=1.17) has been reported. During the routine observation of VLF waves at Jammu, whistlers and different types of VLF/ELF emissions such as whistlers of varying dispersion confined to a small band limited frequency range, hisslers, pulsing hiss, discrete chorus emissions of rising and falling tones with multiple bands, oscillating tone discrete emission, whistler-triggered hook and discrete chorus risers emissions, etc. have been observed simultaneously during the quiet period on a single night. Such type of unique simultaneous observations has never been reported from any of the low latitude ground stations and this is the first observation of its kind. The results are discussed in the light of recorded features of whistlers and emissions. Generation and propagation mechanism are discussed briefly. Plasma parameters are further derived from the dispersion analysis of nighttime whistlers and emissions recorded simultaneously during magnetically quiet periods.

  16. Drifting Quasi-Periodic Modulation of the Fast Magnetosonic Mode: Van Allen Probe Observations

    NASA Astrophysics Data System (ADS)

    Boardsen, S. A.; Hospodarsky, G. B.; Kletzing, C.; Pfaff, R. F., Jr.; Kurth, W. S.; Wygant, J. R.; MacDonald, E.

    2014-12-01

    The fast magnetosonic mode is one of the dominant wave modes in the Earth's radiation belts. These waves influence the ring current by scattering ions in energy in the 10's of keV range, and are believed to be a heat source for radiation belt electrons. The fast magnetosonic mode observed around the Earth's inner equatorial magnetosphere sometimes exhibits quasi-periodic modulation as detected by the Van Allen probes. During each modulation the wave frequency exhibits a strong drifting (dispersive) signature characterized by a rising tone. Each tone is composed of harmonics with spacing close to the proton cyclotron frequency. The tones are band limited in frequency and mainly observed above the 20th harmonic of the local proton cyclotron frequency. We observe this modulation mainly outside the plasmapause, but it has also been observed to penetrate down to 1.5 RE. The modulation is observed up to magnetic latitudes of ±17º, at all magnetic local times, but its signatures are more pronounced on the dayside. For events where lower frequency ULF waves are detected, the period of the ULF wave is about twice the modulation period of the fast magnetosonic mode, suggesting strong wave-wave interactions. The modulation period varies from 50 to 200 s and its duration ranges from 0.2 to 3 h, with the maximum duration limited by the spacecraft orbit. We hypothesize that the rising tone is produced by changing Alfven velocities created by steepened density fluctuations due to plasma modification by an underlying ULF wave.

  17. Influence of 3 months endurance training on red cell deformability in non insulin dependent type 2 diabetes mellitus patients.

    PubMed

    Ahmad, B; Opitz, D; Bloch, W; Brixius, K

    2013-08-01

    The main purpose of the study was to examine if 3 months of bicycle endurance training alters the red cell deformability in non insulin dependent type 2 diabetes mellitus men.The red cell deformability was measured with the Laser assisted optical rotational cell analyzer. The maximal elongation index and the semimaximal shear stress were measured with the Lineweaver Burke model.At the beginning and the end of the intervention the patients passed a bicycle ergometry test. As a reference group, 13 males without diabetes passed the same testing procedure. Blood samplings were taken before testing, immediately after physical exhaustion and after a 30 min recovery phase.After the training period diabetic patients could significantly reduce BMI, fasting glucose and HbA1c. The reference group had significantly higher elongation indices than the diabetes patients independent from training status. After the training period the basal values of the maximal elongation index did not change significantly. However, maximal elongation indices were significantly reduced after physical examination and in resting time.The semimaximal shear stress of diabetes patients did not alter during the training period. In comparison to the reference group semimaximal shear stress was significantly reduced at all measurement times.This pilot study proves that the maximal elongation index is significantly decreased in diabetes mellitus patients. After 3 months endurance training the red cells become more rigid while the semimaximal shear stress remains constant. Further interventions are required to analyze the exact cause of the presented findings.

  18. Elemental GCR Observations during the 2009-2010 Solar Minimum Period

    NASA Technical Reports Server (NTRS)

    Lave, K. A.; Israel, M. H.; Binns, W. R.; Christian, E. R.; Cummings, A. C.; Davis, A. J.; deNolfo, G. A.; Leske, R. A.; Mewaldt, R. A.; Stone, E. C.; vonRosenvinge, T. T.; Wiedenbeck, M. E.

    2013-01-01

    Using observations from the Cosmic Ray Isotope Spectrometer (CRIS) onboard the Advanced Composition Explorer (ACE), we present new measurements of the galactic cosmic ray (GCR) elemental composition and energy spectra for the species B through Ni in the energy range approx. 50-550 MeV/nucleon during the record setting 2009-2010 solar minimum period. These data are compared with our observations from the 1997-1998 solar minimum period, when solar modulation in the heliosphere was somewhat higher. For these species, we find that the intensities during the 2009-2010 solar minimum were approx. 20% higher than those in the previous solar minimum, and in fact were the highest GCR intensities recorded during the space age. Relative abundances for these species during the two solar minimum periods differed by small but statistically significant amounts, which are attributed to the combination of spectral shape differences between primary and secondary GCRs in the interstellar medium and differences between the levels of solar modulation in the two solar minima. We also present the secondary-to-primary ratios B/C and (Sc+Ti+V)/Fe for both solar minimum periods, and demonstrate that these ratios are reasonably well fit by a simple "leaky-box" galactic transport model that is combined with a spherically symmetric solar modulation model.

  19. Substorms observations during two geomagnetically active periods in March 2012 and March 2015

    NASA Astrophysics Data System (ADS)

    Guineva, V.; Despirak, I.; Kozelov, B.

    2016-05-01

    In this work two events of strong geomagnetic activity were examined: the period 7-17 March 2012, which is one of the most disturbed periods during the ascending phase of Solar Cycle 24, and the severe geomagnetic storm on 17-20 March 2015. During the first period four consecutive magnetic storms occurred on 7, 9, 12, and 15 March. These storms were caused by Sheath, MC and HSS, and the detailed scenarios for the storms were different. The second event is a storm of fourth level with Kp = 8, the strongest one during the last four years, the so-called "St. Patrick's Day 2015 Event". A geomagnetic storm of such intensity was observed in September 2011. Our analysis was based on the 10-s sampled IMAGE magnetometers data, the 1-min sampled OMNI solar wind and interplanetary magnetic field (IMF) data and observations of the Multiscale Aurora Imaging Network (MAIN) in Apatity. The particularities in the behaviours of substorms connected with different storms during these two interesting strongly disturbed periods are discussed.

  20. Differential changes in self-reported aspects of interoceptive awareness through 3 months of contemplative training

    PubMed Central

    Bornemann, Boris; Herbert, Beate M.; Mehling, Wolf E.; Singer, Tania

    2015-01-01

    Interoceptive body awareness (IA) is crucial for psychological well-being and plays an important role in many contemplative traditions. However, until recently, standardized self-report measures of IA were scarce, not comprehensive, and the effects of interoceptive training on such measures were largely unknown. The Multidimensional Assessment of Interoceptive Awareness (MAIA) questionnaire measures IA with eight different scales. In the current study, we investigated whether and how these different aspects of IA are influenced by a 3-months contemplative intervention in the context of the ReSource project, in which 148 subjects engaged in daily practices of “Body Scan” and “Breath Meditation.” We developed a German version of the MAIA and tested it in a large and diverse sample (n = 1,076). Internal consistencies were similar to the English version (0.56–0.89), retest reliability was high (rs: 0.66–0.79), and the MAIA showed good convergent and discriminant validity. Importantly, interoceptive training improved five out of eight aspects of IA, compared to a retest control group. Participants with low IA scores at baseline showed the biggest changes. Whereas practice duration only weakly predicted individual differences in change, self-reported liking of the practices and degree of integration into daily life predicted changes on most scales. Interestingly, the magnitude of observed changes varied across scales. The strongest changes were observed for the regulatory aspects of IA, that is, how the body is used for self-regulation in daily life. No significant changes were observed for the Noticing aspect (becoming aware of bodily changes), which is the aspect that is predominantly assessed in other IA measures. This differential pattern underscores the importance to assess IA multi-dimensionally, particularly when interested in enhancement of IA through contemplative practice or other mind–body interventions. PMID:25610410

  1. Five-day inhalation toxicity study of three types of synthetic amorphous silicas in Wistar rats and post-exposure evaluations for up to 3 months.

    PubMed

    Arts, Josje H E; Muijser, Hans; Duistermaat, Evert; Junker, Karin; Kuper, C Frieke

    2007-10-01

    Evidence suggests that short-term animal exposures to synthetic amorphous silicas (SAS) and crystalline silica can provide comparable prediction of toxicity to those of 90-day studies, therefore providing the opportunity to screen these types of substances using short-term rather than 90-day studies. To investigate this hypothesis, the inhalation toxicity of three SAS, precipitated silica Zeosil 45, silica gel Syloid 74, and pyrogenic silica Cab-O-Sil M5 was studied in Wistar rats. Rats were exposed nose-only to concentrations of 1, 5 or 25mg/m(3) of one of the SAS 6h a day for five consecutive days. Positive controls were exposed to 25mg/m(3) crystalline silica (quartz dust), negative controls to clean air. Animals were necropsied the day after the last exposure or 1 or 3 months later. All exposures were tolerated without serious clinical effects, changes in body weight or food intake. Differences in the effects associated with exposure to the three types of SAS were limited and almost exclusively confined to the 1-day post-exposure time point. Silicon levels in tracheobronchial lymph nodes were below the detection limit in all groups at all time points. Silicon was found in the lungs of all high concentration SAS groups 1-day post-exposure, and was cleared 3 months later. Exposure to all three SAS at 25mg/m(3) induced elevations in biomarkers of cytotoxicity in bronchoalveolar lavage fluid (BALf), increases in lung and tracheobronchial lymph node weight and histopathological lung changes 1-day post-exposure. Exposure to all three SAS at 5mg/m(3) induced histopathological changes and changes in BALf only. With all three SAS these effects were transient and, with the exception of slight histopathological lung changes at the higher exposure levels, were reversible during the 3-month recovery period. No adverse changes were observed in animals exposed to any of the SAS at 1mg/m(3). In contrast, with quartz-exposed animals the presence of silicon in the lungs was

  2. Recurrence times and periodicities in 4U 1608-52 as observed by Vela 5B

    NASA Technical Reports Server (NTRS)

    Lochner, James C.; Roussel-Dupre, Diane

    1994-01-01

    We report on the Vela 5B 10 year history of the soft X-ray transient 4U 1608-52, and on the characteristics of its soft X-ray outbursts. The Vela 5B satellite observed the four known outbursts in 1975, 1977, and 1979, and four new outbursts in 1970 and 1971, altering the recurrence pattern of outbursts from this source. One of the 1970 outbursts is symmetric in its intensity profile, while the two outbursts in 1971 have short exponential profiles separated by 80 days. Despite suggestive recurrence periods of approximately 85 and approximately 150 days evident in the time intervals between the outbursts, there is no single statistically significant recurrence time on which the outbursts recur consistently. In the 1970 symmetric event, there is evidence for a period of either 4.10 or 5.19 days. Drawing upon the analogy with SU Ursa Majoris dwarf novae, we suggest that the short period is orbital and any longer period would be associated with a precession period of the accretion disk.

  3. Calibration of Hipparcos Long Period Variable Start Fields Using Multi-Color CCD Observations

    NASA Astrophysics Data System (ADS)

    Howell, Steve B.; Mattei, Janet; Benson, Priscilla J.; Reyes, Adriana

    The first set of 4-color AAVSO CCD finder charts has been prepared using the 0.9-m telescope at Kitt peak national Observatory in Arizona. The stars selected were northern long period variable stars observed with the Hipparcos astrometric satellite, since multicolor photometry was needed on these stars to calibrate and reduce the photometric and astrometric data obtained by the satellite. We describe the criteria in choosing the stars for which to prepare CCD finder charts, the observation process, and the reduction of the CCD to obtain 4-color CCD magnitude sequences to use in the creation of AAVSO finder charts.

  4. Summer weather characteristics and periodicity observed over the period 1888-2013 in the region of Belgrade, Serbia

    NASA Astrophysics Data System (ADS)

    Vujović, Dragana; Todorović, Nedeljko; Paskota, Mira

    2017-02-01

    With the goal of finding summer climate patterns in the region of Belgrade (Serbia) over the period 1888-2013, different techniques of multivariate statistical analysis were used in order to analyze the simultaneous changes of a number of climatologic parameters. An increasing trend of the mean daily minimum temperature was detected. In the recent decades (1960-2013), this increase was much more pronounced. The number of days with the daily minimum temperature greater or equal to 20 °C also increased significantly. Precipitation had no statistically significant trend. Spectral analysis showed a repetitive nature of the climatologic parameters which had periods that roughly can be classified into three groups, with the durations of the following: (1) 6 to 7 years, (2) 10 to 18 years, and (3) 21, 31, and 41 years. The temperature variables mainly had one period of repetitiveness of 5 to 7 years. Among other variables, the correlations of regional fluctuations of the temperature and precipitation and atmospheric circulation indices were analyzed. The North Atlantic oscillation index had the same periodicity as that of the precipitation, and it was not correlated to the temperature variables. Atlantic multidecadal oscillation index correlated well to the summer mean daily minimum and summer mean temperatures. The underlying structure of the data was analyzed by principal component analysis, which detected the following four easily interpreted dimensions: More sunshine-Higher temperature, Precipitation, Extreme heats, and Changeable summer.

  5. Overview of the first HyMeX special observation period over Croatia

    NASA Astrophysics Data System (ADS)

    Ivančan-Picek, Branka; Tudor, Martina; Horvath, Kristian; Stanešić, Antonio; Ivatek-Šahdan, Stjepan

    2016-12-01

    The HYdrological cycle in the Mediterranean EXperiment (HyMeX) is intended to improve the capabilities of predicting high-impact weather events. Within its framework, the aim of the first special observation period (SOP1), 5 September to 6 November 2012, was to study heavy precipitation events and flash floods. Here, we present high-impact weather events over Croatia that occurred during SOP1. Particular attention is given to eight intense observation periods (IOPs), during which high precipitation occurred over the eastern Adriatic and Dinaric Alps. During the entire SOP1, the operational model forecasts generally well represented medium intensity precipitation, but heavy precipitation was frequently underestimated by the ALADIN model at an 8 km grid spacing and was overestimated at a higher resolution (2 km grid spacing). During IOP2, intensive rainfall occurred over a wider area around the city of Rijeka in the northern Adriatic. The short-range maximum rainfall totals were the largest ever recorded at the Rijeka station since the beginning of measurements in 1958. The rainfall amounts measured in intervals of 20, 30 and 40 min were exceptional, with return periods that exceeded a thousand, a few hundred and one hundred years, respectively. The operational precipitation forecast using the ALADIN model at an 8 km grid spacing provided guidance regarding the event but underestimated the rainfall intensity. An evaluation of numerical sensitivity experiments suggested that the forecast was slightly enhanced by improving the initial conditions through variational data assimilation. The operational non-hydrostatic run at a 2 km grid spacing using a configuration with the ALARO physics package further improved the forecast. This article highlights the need for an intensive observation period in the future over the Adriatic region to validate the simulated mechanisms and improve numerical weather predictions via data assimilation and model improvements in descriptions

  6. Management of Toxoplasmic Retinochoroiditis during Pregnancy, Postpartum Period and Lactation: Clinical Observations

    PubMed Central

    Brydak-Godowska, Joanna; Moneta-Wielgoś, Joanna; Kęcik, Dariusz; Borkowski, Piotr Karol

    2015-01-01

    Background During pregnancy and labor, the immune response is physiologically impaired and women are more susceptible to infections. Since many drugs may have potentially adverse effects on the fetus and newborn, less aggressive treatment regimens should be considered in pregnant and lactating patients. The aim of our study was to present the management of toxoplasmic retinochoroiditis during pregnancy, postpartum period, and lactation. Material/Methods A retrospective study was undertaken of the clinical records of 24 women during pregnancy, postpartum period, and lactation who were referred in the years 1994–2014 to the Department of Zoonoses and Tropical Diseases or the Department of Ophthalmology, Medical University of Warsaw for toxoplasmic retinochoroiditis. The diagnosis was based on the typical ophthalmoscopic picture, confirmed by serological testing using an ELISA method. Results A total of 28 attacks of toxoplasmic retinochoroiditis were observed in 24 patients during pregnancy, postpartum period, and lactation. The choice of treatment was guided by the character and location of the inflammatory lesion and the gestational age. Topical (steroidal/nonsteroidal eye drops) and systemic treatments with spiramycin or azithromycin, Fansidar (pyrimethamine 25 mg/sulfadoxine 500 mg), and prednisone were used. Conclusions Management of toxoplasmic retinochoroiditis during pregnancy, postpartum period, or lactation must be individualized and guided by the gestational age and location of the active lesion. Women of childbearing age with toxoplasma ocular lesions should be informed by their doctors about possible active recurrences during pregnancy and followed carefully by an ophthalmologist when pregnant. PMID:25711713

  7. Confrontation Between a Quantized Periods of Some Exo-planetary Systems and Observations

    NASA Astrophysics Data System (ADS)

    El Fady Morcos, Abd

    2012-07-01

    Confrontation Between a Quantized Periods of Some Exo-planetary Systems and Observations A.B. Morcos Corot and Kepler were designed to detect Earth-like extra solar planets. The orbital elements and periods of these planets will contain some uncertainties. Many theoretical treatments depend on the idea of quantization were done aiming to find orbital elements of these exoplenets. In the present work, as an extension of previous works, the periods of some extoplanetary systems are calculated by using a simple derived formula. The orbital velocities of some of them are predicted . A comparison between the calculated and observed data is done References 1-J.M. Barnothy , the stability of the Solar System and of small Stellar Systems . (Y.Kazai edn,IAU,1974). 2-L.Nottale,Fractal Space-Time and Microphysics,Towards a Theory of Scale Relativity,( World Scientific, London,1994). 3-L. Nottale, A&A Lett. 315, L9 (1996). 4-L. Nottale, G. Schumacher and J. Gay, A&A , 322, 1018 , (1997). 5-L. Nottale, A&A , 361, 379 (2000). 6-A.G. Agnese and R.Festa, arXiv:astro-ph/9807186v1, (1998). 7-A.G. Agnese and R.Festa, arXiv:astro-ph/9910534v2. (1999). 8- A.B.Morcos, MG 12 , France (2009). 9- A.B.Morcs, Cospar 38 , Bremen , Germany (2010)

  8. "Zipper-like" periodic magnetosonic waves: Van Allen Probes, THEMIS, and magnetospheric multiscale observations

    NASA Astrophysics Data System (ADS)

    Li, J.; Bortnik, J.; Li, W.; Ma, Q.; Thorne, R. M.; Kletzing, C. A.; Kurth, W. S.; Hospodarsky, G. B.; Wygant, J.; Breneman, A.; Thaller, S.; Funsten, H. O.; Mitchell, D. G.; Manweiler, J. W.; Torbert, R. B.; Le Contel, O.; Ergun, R. E.; Lindqvist, P.-A.; Torkar, K.; Nakamura, R.; Andriopoulou, M.; Russell, C. T.

    2017-02-01

    An interesting form of "zipper-like" magnetosonic waves consisting of two bands of interleaved periodic rising-tone spectra was newly observed by the Van Allen Probes, the Time History of Events and Macroscale Interactions during Substorms (THEMIS), and the Magnetospheric Multiscale (MMS) missions. The two discrete bands are distinct in frequency and intensity; however, they maintain the same periodicity which varies in space and time, suggesting that they possibly originate from one single source intrinsically. In one event, the zipper-like magnetosonic waves exhibit the same periodicity as a constant-frequency magnetosonic wave and an electrostatic emission, but the modulation comes from neither density fluctuations nor ULF waves. A statistical survey based on 3.5 years of multisatellite observations shows that zipper-like magnetosonic waves mainly occur on the dawnside to noonside, in a frequency range between 10 fcp and fLHR. The zipper-like magnetosonic waves may provide a new clue to nonlinear excitation or modulation process, while its cause still remains to be fully understood.

  9. Observations of Very-Long-Period Tremor at the Tatun Volcano Group, Northern Taiwan

    NASA Astrophysics Data System (ADS)

    Yeh, Y.; Lin, C.; Konstantino, K.

    2006-12-01

    The Tatun Volcano Group lies at the northern tip of Taiwan and is only 15 km north of the capital Taipei, which has more than seven million inhabitants. To examine the possibility of both volcanic and seismic activity in the future, a dense seismic array consisting of 8 stations equipped with both broad-band and short-period sensors has been installed in Tatun area since 2003. In addition to common volcano-tectonic earthquakes, we have observed a variety of volcanoseismic signals such as tornillos, short duration monochromatic events and long duration spasmodic bursts from the short-period seismic data. Further examination of broadband seismic data shows that there also were some very-long-period (VLP) volcanic signals, which are often reported at some active volcanoes in the world. Based on the polarization and travel-time of the VLP signals recorded at 4 broadband stations, the source of VLP seismic signals was located at a depth around 2.0 km. These observations put into doubt the long-standing suggestion that the Tatun volcanoes are extinct and prompt for a thorough assessment of the volcanic hazard for this area.

  10. Observations of Quasi-Periodic Whistler Mode Waves by the Van Allen Probes

    NASA Astrophysics Data System (ADS)

    Hospodarsky, George; Wilkinson, Darrelle; Kurth, William; Kletzing, Craig; Santolik, Ondrej

    2016-10-01

    Observed in Earth's inner magnetosphere, quasi-periodic whistler mode emissions (QP) are electromagnetic waves in the frequency range from a few hundred Hz to a few kHz that exhibit a periodic modulation (typically a few minutes) of their wave intensity. These waves were first detected at high latitude ground stations, but more recently have been observed by a number of spacecraft, including the twin Van Allen Probes. The Electric and Magnetic Field Instrument Suite and Integrated Science (EMFISIS) instrument simultaneously measures the vector wave magnetic field and electric field, allowing wave propagation parameters, such as wave normal angle and Poynting vector, to be obtained. Almost four years of Van Allen Probes data have been examined and a statistical survey of the occurrence and properties of the QP emissions has been performed. The QP emissions were found to have periods ranging from 1 to 16 minutes with events lasting from less than 1 hour up to 6 hours. Some events were detected on successive orbits and a number of events were simultaneously detected by both spacecraft, even during large spacecraft separations, providing an opportunity to investigate the source and propagation properties of these waves.

  11. HST Observations of a Large-Amplitude, Long-Period Trojan: (11351) Leucus

    NASA Astrophysics Data System (ADS)

    Noll, Keith S.; Levison, Harold F.; Buie, Marc W.; Grundy, William M.

    2016-10-01

    (11351) Leucus (1997 TS25) is a Trojan that is notable for having one of the longest known rotation periods of any small body, T=514 h. A possible cause for this long period would be the existence of a tidally locked binary similar to the already-known long period binary Trojan, (617) Patroclus. If this were the case, the system would become tidally circularized in a time short compared to the age of the solar system. In such a case, the components would be separated by ~0.18 arcsec at lightcurve maximum, resolvable by WFC3. We carried out observations in June 2016, coordinated with groundbased observations to schedule near a maximum to test whether (11351) Leucus is binary. We describe the results of these observations.Observations of (11351) Leucus are of particular interest because it is a target of the Lucy mission, a Discovery mission currently in phase A and one of five that may be selected in early 2017. Searches for binary Trojans also offer multiple scientific benefits independent of mission status. Orbit-derived mass and density can be used to constrain planetary migration models. Low density is characteristic of bodies found in the dynamically cold Kuiper Belt, a remnant of the solar system's protoplanetary disk. Only one undisputed density has been measured in the Trojans, that of the binary (617) Patroclus, which has a low density of 0.8 g/cm3, similar to the low densities found in the Kuiper Belt. Slow rotators offer a set of targets that are tidally evolved systems and therefore are among the most attractive potential targets for an HST search.

  12. Seasonal and Interannual Variability of Short Period Lamb Waves Observed over South Pole

    NASA Astrophysics Data System (ADS)

    Palo, S.; Gerhardt, D.

    2009-12-01

    A meteor radar system was installed at Amundsen-Scott South Pole station in 2001 and became fully operational in 2002. This radar has operated nearly continuously since and is providing horizontal wind measurements in four separate azimuth directions. This feature provides the ability to determine the zonal wavenumber and direction of propagation for the observed perturbations. With multiple years of observations we have the opportunity to investigate the coherent seasonal structure of the large scale observations over South Pole. These include the migrating diurnal and semidiurnal oscillations which are large during the summer months as well as both eastward and westward propagating planetary waves. Throughout the year short period (8-14) hour oscillations are present and have been associated with Lamb Waves. In this paper we present a spatial and temporal analysis of these planetary waves.

  13. Observing and Modeling Long-Period Tidal Variations in Polar Motion

    NASA Technical Reports Server (NTRS)

    Gross, Richard S.; Dickman, S. R.

    2011-01-01

    By exchanging angular momentum with the solid Earth, ocean tides cause the Earth's rotation to change. While hydrodynamic tide models have been used to study the effect of ocean tides on polar motion, it is shown here that none of the published models can fully account for the observed variations. An empirical ocean tide model is therefore determined by fitting periodic terms at the tidal frequencies to polar motion excitation observations, from which atmospheric and non-tidal oceanic effects were removed. While the empirical ocean tide model does fully account for allof the observed tidal power, tests indicate that the model may not have completely converged. So better models of the effects of ocean tides on polar motion are still needed, both dynamical and empirical.

  14. Periodicity in the spatial-temporal earthquake distributions for the Pacific region: observation and modeling.

    NASA Astrophysics Data System (ADS)

    Sasorova, Elena; Levin, Boris

    2014-05-01

    In the course of the last century a cyclic increasing and decreasing of the Earth's seismic activity (SA) was marked. The variations of the SA for the events with M>=7.0 from 1900 up to date were under study. The two subsets of the worldwide NEIC (USGS) catalog were used: USGS/NEIC from 1973 to 2012 and catalog of the significant worldwide earthquakes (2150 B.C. - 1994 A.D.), compiled by USGS/NEIC from the NOAA agency. The preliminary standardization of magnitudes and elimination of aftershocks from list of events was performed. The entire period of observations was subdivided into 5-year intervals. The temporal distributions of the earthquake (EQ) density and released energy density were calculated separately for the Southern hemisphere (SH), and for the Northern hemisphere (NH) and for eighteen latitudinal belts: 90°-80°N, 80°-70°N, 70°-60°N, 60°-50°N and so on (the size of each belt is equal to 10°). The periods of the SA was compared for different latitudinal belts of the Earth. The peaks and decays of the seismicity do not coincide in time for different latitudinal belts and especially for the belts located in NH and SH. The peaks and decays of the SA for the events (with M>=8) were marked in the temporal distributions of the EQ for all studied latitudinal belts. The two-dimension distributions (over latitudes and over time) of the EQ density and released energy density highlighted that the periods of amplification of the SA are equal to 30-35 years approximately. Next, we check the existence of a non-random component in the EQ occurrence between the NH and the SH. All events were related to the time axis according to their origin time. We take into consideration the set of the EQs in the studied catalog as the sequence of events if each event may have only one of two possible outcome (occurrence in the NH or in the SH). A nonparametric run test was used for testing of hypothesis about an existence the nonrandom component in the examined sequence of

  15. Observations of 20-day period meridional current oscillations in the upper ocean along the Pacific Equator

    NASA Technical Reports Server (NTRS)

    Halpern, David; Knox, Robert A.; Luther, Douglas S.

    1988-01-01

    Prominent oscillations of the meridional current, with a mean period of approximately 20 days, is observed in the upper ocean from May 1979 to October 1985 using moored current measurements along the Pacific equator at 95, 110, 124, 140, and 152 deg W, as well as off (but near) the equator at 110 and 140 deg W. The fluctuations are relatively narrowband in frequency. A 95 percent statistically significant peak in the power spectra of the meridional current occurs at 110, 124, and 140 deg W, but not at 95 and 152 deg W where the spectral peaks are smaller. The dominant wave period decreases by about 4 percent from 110 to 140 deg W. The wave amplitude decreases with depth, and the wave is essentially confined to the upper 80 m. The penetration depth of the oscillation is greatest at 110 deg W and least at 140 deg W.

  16. On quasi-periodic variations of low-energy cosmic rays observed near earth.

    PubMed

    Kudela, Karel; Langer, Ronald

    2015-06-01

    Cosmic ray (CR) may partially, especially at high altitudes, contribute to the dosimetric characteristics. Along with irregular CR variations as Forbush decreases and solar particle events are, the quasi-periodic variations may be of some relevance too. A very short review (with references to original papers) of the present knowledge of various types of such variations is presented, namely (i) diurnal wave, (ii) ~27 d variability due to the solar rotation, (iii) Rieger-type periodicity, and (iv) quasi-biennial oscillations as well as waves on longer time scales related to solar activity and to polarity of magnetic field of the Sun. Variability is illustrated in measurements of secondary CR on the ground including the high-altitude observations at Lomnický štít.

  17. SOHO/SWAN OBSERVATIONS OF SHORT-PERIOD SPACECRAFT TARGET COMETS

    SciTech Connect

    Combi, M. R.; Lee, Y.; Patel, T. S.; Maekinen, J. T. T.; Bertaux, J.-L.; Quemerais, E.

    2011-04-15

    SWAN, the Solar Wind ANisotropies all-sky hydrogen Ly{alpha} camera on the Solar and Heliospheric Observatory spacecraft that makes all-sky images of interplanetary neutral hydrogen, has an ongoing campaign to make special observations of comets, both short- and long-period ones, in addition to the serendipitous observations of comets as part of the all-sky monitoring program. We report here on a study of several short-period comets that were detected by SWAN: 21P/Giacobini-Zinner (1998 and 2005 apparitions), 19P/Borrelly (2001 apparition), 81P/Wild 2 (1997 apparition), and 103P/Hartley 2 (1997 apparition). SWAN observes comets over long continuous stretches of their visible apparitions and therefore provides excellent temporal coverage of the water production. For some of the observations we are also able to analyze an entire sequence of images over many days to several weeks/months using our time-resolved model and extract daily average water production rates over continuous periods of several days to months. The short-term (outburst) and long-term behavior can be correlated with other observations. The overall long-term variation is examined in light of seasonal effects seen in the pre- to post-perihelion differences. For 21P/Giacobini-Zinner and 81P/Wild 2 the activity variations over each apparition were more continuously monitored but nonetheless consistent with previous observations. For 19P/Borrelly we found a very steep variation of water production rates, again consistent with some previous observations, and a variation over six months around perihelion that was reasonably consistent with the spin-axis model of Schleicher et al. and the illumination of the main active areas. During the 1997-1998 apparition of 103P/Hartley 2, the target comet of the EPOXI mission (the Deep Impact extended mission), we found a variation with heliocentric distance ({approx}r{sup -3.6}) that was almost as steep as 19P/Borrelly and, given the small measured radius near

  18. Observational survey of the puzzling star HD 179821: Photometric variations and period analysis

    NASA Astrophysics Data System (ADS)

    Le Coroller, H.; Lèbre, A.; Gillet, D.; Chapellier, E.

    2003-03-01

    From new photometric observations (UBVRI), we present the characteristic features of the light variations of the evolved star HD 179821 (= SAO 124414 = IRAS 19114+0002). Our data, collected through 1999 and 2000, have been combined together with previous photometric measurements available in the literature. Thus, a long term V-light curve (gathering more than 10 years of observations for HD 179821) has been composed. We have analysed it with the Fourier transform method. Two main frequencies are present in the resulting power spectrum, reflecting a dominant bimodal pulsator behavior. A long term phenomenon is also found, but it is not possible to decide whether it is periodic. The Fourier analysis has also been applied on two other filters (U and B) and confirms the detected frequencies. On the basis of our period analysis, we discuss the nature of HD 179821: low-mass post-AGB star or high-mass star. based on observations carried out at the Observatoire de Haute Provence, France, operated by the Centre National de la Recherche Scientifique (CNRS).

  19. Subarcsecond bright points and quasi-periodic upflows below a quiescent filament observed by IRIS

    NASA Astrophysics Data System (ADS)

    Li, T.; Zhang, J.

    2016-05-01

    Context. The new Interface Region Imaging Spectrograph (IRIS) mission provides high-resolution observations of UV spectra and slit-jaw images (SJIs). These data have become available for investigating the dynamic features in the transition region (TR) below the on-disk filaments. Aims: The driver of "counter-streaming" flows along the filament spine is still unknown yet. The magnetic structures and the upflows at the footpoints of the filaments and their relations with the filament mainbody have not been well understood. We study the dynamic evolution at the footpoints of filaments in order to find some clues for solving these questions. Methods: Using UV spectra and SJIs from the IRIS, along with coronal images and magnetograms from the Solar Dynamics Observatory (SDO), we present the new features in a quiescent filament channel: subarcsecond bright points (BPs) and quasi-periodic upflows. Results: The BPs in the TR have a spatial scale of about 350-580 km and lifetimes of more than several tens of minutes. They are located at stronger magnetic structures in the filament channel with a magnetic flux of about 1017-1018 Mx. Quasi-periodic brightenings and upflows are observed in the BPs, and the period is about 4-5 min. The BP and the associated jet-like upflow comprise a "tadpole-shaped" structure. The upflows move along bright filament threads, and their directions are almost parallel to the spine of the filament. The upflows initiated from the BPs with opposite polarity magnetic fields have opposite directions. The velocity of the upflows in the plane of sky is about 5-50 km s-1. The emission line of Si IV 1402.77 Å at the locations of upflows exhibits obvious blueshifts of about 5-30 km s-1, and the line profile is broadened with the width of more than 20 km s-1. Conclusions: The BPs seem to be the bases of filament threads, and the upflows are able to convey mass for the dynamic balance of the filament. The "counter-streaming" flows in previous observations

  20. Direct experimental observation of periodic intensity modulation along a straight hollow-core optical waveguide

    SciTech Connect

    Pfeifer, T.; Downer, M. C.

    2007-05-15

    We report the direct observation of periodic intensity modulation of a laser pulse propagating in a hollow-core waveguide. A series of equally spaced plasma sparks along the gas-filled capillary is produced. This effect can be explained by the beating of different fiber modes, which are excited by controlling the size of the focal spot at the capillary entrance. As compared with an artificial modulated waveguide structure, our presented approach represents an easier and more flexible quasi-phase-matching scheme for nonlinear-optical frequency conversion.

  1. A randomized controlled trial of brain training with non-action video games in older adults: results of the 3-month follow-up.

    PubMed

    Ballesteros, Soledad; Mayas, Julia; Prieto, Antonio; Toril, Pilar; Pita, Carmen; Laura, Ponce de León; Reales, José M; Waterworth, John A

    2015-01-01

    This randomized controlled study (ClinicalTrials.gov NCT02007616) investigated the maintenance of training effects of 20 1-hr non-action video game training sessions with selected games from a commercial package on several age-declining cognitive functions and subjective wellbeing after a 3-month no-contact period. Two groups of cognitively normal older adults participated in both the post-training (posttest) and the present follow-up study, the experimental group who received training and the control group who attended several meetings with the research team during the study but did not receive training. Groups were similar at baseline on demographics, vocabulary, global cognition, and depression status. Significant improvements in the trained group, and no variation in the control group had been previously found at posttest, in processing speed, attention and visual recognition memory, as well as in two dimensions of subjective wellbeing. In the current study, improvement from baseline to 3 months follow-up was found only in wellbeing (Affection and Assertivity dimensions) in the trained group whereas there was no change in the control group. Previous significant improvements in processing speed, attention and spatial memory become non-significant after the 3-month interval. Training older adults with non-action video games enhanced aspects of cognition just after training but this effect disappeared after a 3-month no-contact follow-up period. Cognitive plasticity can be induced in older adults by training, but to maintain the benefits periodic boosting sessions would be necessary.

  2. Observation of gamma rays with a 4.8 hour periodicity from CYG X-3

    NASA Technical Reports Server (NTRS)

    Lamb, R. C.; Fichtel, C. E.; Hartman, R. C.; Kniffen, D. A.; Thompson, D. J.

    1976-01-01

    Energetic (E35 MeV) Gamma rays were observed from Cyg X-3 with the SAS-2 Gamma ray telescope. They are modulated at the 4.8 sup h period observed in the X-ray and infrared regions, and within the statistical error are in phase with this emission. The flux above 100 MeV has an average value of (4.4 + or - 1.1)x 10 to the -6 power/sq cm/sec. If the distance to Cyg X-3 is 10 kpcs, this flux implies a luminosity of more than 10 to the 37th power ergs/s if the radiation is isotropic and about 10 to the 36th power ergs/s if the radiation is restricted to a cone of one steradian, as it might be in a pulsar.

  3. Mental Rotation of Dynamic, Three-Dimensional Stimuli by 3-Month-Old Infants

    ERIC Educational Resources Information Center

    Moore, David S.; Johnson, Scott P.

    2011-01-01

    Mental rotation involves transforming a mental image of an object so as to accurately predict how the object would look if it were rotated in space. This study examined mental rotation in male and female 3-month-olds, using the stimuli and paradigm developed by Moore and Johnson (2008). Infants were habituated to a video of a three-dimensional…

  4. Stability and Changes in Sleep Regulation: A Longitudinal Study from 3 Months to 3 Years

    ERIC Educational Resources Information Center

    Scher, Anat; Epstein, Rachel; Tirosh, Emmanuel

    2004-01-01

    The goal of the study was to examine the developmental course of sleep consolidation from infancy to preschool. The sleep of 50 healthy infants aged 3 months was recorded, at home, with actigraphs (computerised activity monitors). Follow-up recordings were carried out at 6, 9, 12, 20, and 42 months (due to attrition and occasional technical…

  5. The Face Perception System becomes Species-Specific at 3 Months: An Eye-Tracking Study

    ERIC Educational Resources Information Center

    Di Giorgio, Elisa; Meary, David; Pascalis, Olivier; Simion, Francesca

    2013-01-01

    The current study aimed at investigating own- vs. other-species preferences in 3-month-old infants. The infants' eye movements were recorded during a visual preference paradigm to assess whether they show a preference for own-species faces when contrasted with other-species faces. Human and monkey faces, equated for all low-level perceptual…

  6. Positive, but Not Negative, Facial Expressions Facilitate 3-Month-Olds' Recognition of an Individual Face

    ERIC Educational Resources Information Center

    Brenna, Viola; Proietti, Valentina; Montirosso, Rosario; Turati, Chiara

    2013-01-01

    The current study examined whether and how the presence of a positive or a negative emotional expression may affect the face recognition process at 3 months of age. Using a familiarization procedure, Experiment 1 demonstrated that positive (i.e., happiness), but not negative (i.e., fear and anger) facial expressions facilitate infants' ability to…

  7. A Smile Enhances 3-Month-Olds' Recognition of an Individual Face

    ERIC Educational Resources Information Center

    Turati, Chiara; Montirosso, Rosario; Brenna, Viola; Ferrara, Veronica; Borgatti, Renato

    2011-01-01

    Recent studies demonstrated that in adults and children recognition of face identity and facial expression mutually interact (Bate, Haslam, & Hodgson, 2009; Spangler, Schwarzer, Korell, & Maier-Karius, 2010). Here, using a familiarization paradigm, we explored the relation between these processes in early infancy, investigating whether 3-month-old…

  8. Identifying predictors of resilience at inpatient and 3-month post-spinal cord injury

    PubMed Central

    Warren, Ann Marie; Reynolds, Megan; Agtarap, Stephanie; Hamilton, Rita; Trost, Zina; Monden, Kimberly

    2016-01-01

    Objectives To identify (1) changes in psychosocial factors, (2) relationships between psychosocial factors, and (3) significant predictors of resilience in adults with spinal cord injury (SCI) during inpatient rehabilitation and at 3-month post-discharge. Design Cross sectional with convenience sample based on inclusion/exclusion criteria. Setting Inpatient rehabilitation hospital and community-based follow-up. Participants Individuals with a SCI. Interventions Not applicable. Outcome measures Demographic, resilience, self-efficacy for managing a chronic health issue, depression, social roles/activity limitations, and pain. Results The final sample consisted of 44 respondents (16 women and 28 men). Results of repeated measure analyses of variance indicated no significant changes in variables between inpatient and 3-month follow-up. Bivariate correlations revealed associations between resilience and self-efficacy at inpatient (r = 0.54, P < 0.001), and resilience and depression (r = −0.69, P < 0.001) and self-efficacy (r = 0.67, P < 0.001) at 3-month follow-up. Hierarchical regression analyses a significant model predicting resilience at inpatient stay (R = 0.61; adjusted R2 = 0.24, P = 0.023), and at 3-month follow-up (R = 0.83; adjusted R2 = 0.49, P = 0.022). Self-efficacy was the strongest predictor at inpatient stay (β = 0.46, P  =  0.006) and depression was strongest at 3-month follow-up (β = −0.80, P = 0.007). Conclusion Results suggest that although resilience appears to be stable from inpatient to 3-month follow-up, different factors are stronger predictors of resilience across time. Based on current results, an assessment of self-efficacy during inpatient rehabilitation and an identification of depression at 3-month follow-up may be important factors to help identify those at risk of health issues overtime. PMID:25297474

  9. Quasi-periodic frequency fluctuations observed during coronal radio sounding experiments 1991-2009

    NASA Astrophysics Data System (ADS)

    Efimov, Anatoli; Lukanina, L. A.; Samoznaev, Lev; Rudash, V. K.; Chashei, Igor; Bird, Michael; Paetzold, Martin

    Recent coronal radio sounding experiments with the ESA spacecraft Mars Express (MEX), Venus Express (VEX) and Rosetta (ROS) have provided a large volume of observational data supporting the presence of a quasi-periodic component (QPC) in frequency fluctuation spectra during solar conjunction. Further evidence for the QPC, first seen in data from the MEX conjunction in 2004, was found later in data from the MEX conjunctions in 2006 and 2008/09, as well as the VEX and ROS conjunctions in 2006. The QPC is detected with an occurrence frequency ≈ 18% (83.3 hours of the total 462.7 hours of data). In some cases the temporal spectra reveal two lines: the main QPC and its second harmonic. The average frequency of the spectral density maximum is νmax ≈ 5.5 mHz (corresponding QPC fluctuation period ≈ 3 min) at solar offset distances R < 8 Rs. The QPC spectral density maximum Gmax reaches an average factor of 2.88 above the background level G0 . The bandwidth of the spectral line ∆ν ≈ νmax . At larger solar distances (R > 8 Rs) the fluctuation frequency of the mean spectral density maximum is νmax ≈ 4.3 mHz (period ≈ 4 min). Both the fractional spectral line bandwidth ∆ν/νmax and the excess of spectral density Gmax above background are nearly unchanged from their values nearer the Sun. A reanalysis of earlier coronal sounding data obtained with the Ulysses (1991, 1995) and Galileo (1996/97) spacecraft has verified the existence of the QPC. Typical fluctuation periods lie between 4 and 5 min, but the QPC occurrence rate (12%) is smaller than that observed for MEX-VEX-ROS. This may be associated with the lower received signal level of Ulysses and Galileo compared to the ESA spacecraft. The Ulysses coronal sounding experiments in 1995 provided an interesting possibility to observe the QPC at high solar latitudes. Preliminary results show that the QPC frequency can reach νmax = 6-7 mHz at heliolatitudes 60° -80° .

  10. Observations and predictions of eclipse times by astronomers in the pre-telescopic period.

    NASA Astrophysics Data System (ADS)

    Steele, J. M.

    Eclipses of the Sun and Moon are among the most impressive of celestial events. It is therefore unsurprising that they have played an important role in the astronomy and astrology of most early cultures. Many hundreds of references to eclipses are found in the writings of the chroniclers and astronomers of the pre-telescopic world. In particular, the astronomers of Babylon, Ancient Greece, the Islamic Near East. Later Medieval and Renaissance Europe, China, and Japan, recorded a large number of observations and predictions of the time of an eclipse. The present study contains an extensive compilation of all known timed reports of eclipse observations and predictions made by astronomers in the pre-telescopic period. By performing a basic analysis of the recorded times, it has been possible to trace the gradual development of the techniques used by the astronomers to observe and predict eclipses. In order to conduct this analysis, it has been necessary to investigate a number of other problems including the dating of damaged observational accounts, the units of time used by the early astronomers, and the methods by which the Babylonians predicted eclipses. Many of these questions have not previously been answered. Therefore, the results of this study provide important information regarding the astronomies of these early cultures.

  11. The French component of the FENNEC Saharan Climate project 2011 Special Observing Period

    NASA Astrophysics Data System (ADS)

    Flamant, C.; Chaboureau, J.-P.; Kocha, C.; Lavaysse, C.; Schepanski, K.; Chazette, P.; Bock, O.; Marticorena, B.; Tulet, P.; Pelon, J.; Marnas, F.; Mokhtari, M.; Lafore, J.-P.; Roehrig, R.; Koulali Idrissi, A.; Tsamalis, C.; Chedin, A.

    2012-04-01

    The central Sahara has one of the most extreme climates on Earth. During the northern summer months, a large low pressure system caused by intense solar heating develops over a huge, largely uninhabited expanse of northern Mali, southern Algeria and eastern Mauritania. This Saharan heat low plays a pivotal role in the West African Monsoon. Based on this, the interested French, British and German communities have decided to propose the FENNEC project which aims at (i) characterizing the Saharan atmospheric boundary layer, (ii) evaluating its representation in regional and global models, and (iii) improving "aerosol" products issued from space-borne observations. A key element of this programme was the organization of an international field campaign in June 2011 over the Saharan heat low region, which will include both ground-based and airborne detachments. The Special Observing Period component of FENNEC-France included the implementation of the SAFIRE Falcon 20 to conduct research on the atmospheric boundary layer and the dust cycle of the Sahara, the installation of a remote sensing station in southern Spain, equipped with a backscatter lidar and a sunphotometer, to study the transport of desert dust to Europe, as well as a couple of GPS stations installed in southern Morocco to investigate the moisture inflow from the Atlantic Ocean into the Sahara. For the first time, the ALADIN and AROME models (5 and 24 km grid spacing, respectively) have been implemented operationally to provide forecasts of dust events over the Sahara and parts of the Sahel in June 2011 to assist in planning for airborne operations. This effort was complemented by the forecasts made with the Meso-NH model (5 and 20 km resolution). During the SOP period, the ground-based, airborne and space-borne observations have documented the evolution of dynamic properties of thermodynamic and the atmospheric boundary layer Saharan Africa (Mauritania and Mali) during the installation phase of the Saharan

  12. Deciphering IR Excess Observed by the Spitzer Space Telescope in Short Period Interacting Cataclysmic Binaries

    NASA Astrophysics Data System (ADS)

    Chun, Howard; Brinkworth, Carolyn; Ciardi, David; Hoard, Don; Howell, Steve; Stefaniak, Linda; Thomas, , Beth

    2006-03-01

    During the first year of the Spitzer Space Telescope Observing Program for Students and Teachers, our team observed a small sample of short orbital period interacting white dwarf binaries. Our scientific investigation was aimed at detection and characterization of the low mass, cool, brown dwarf-like mass donors in these systems. We used the Infrared Array Camera to obtain photometric observations of the polars EF Eri, GG Leo, V347 Pav, and RX J0154.0-5947 at 3.6, 4.5, 5.8, and 8.0 microns. In all our targets, we detected excess emission in the 3-8 micron region over that expected from a brown dwarf alone. One of the exciting discoveries we made with our IRAC observations is that the star EF Eri was found to be unexpectedly bright in the mid-IR (compared to its 2MASS magnitudes). This fact highlights an opportunity for us to observe EF Eri with the IRS as a follow-up proposal. EF Eri has a flux level of ~700 ?Jy at 8 microns. Thus, we are asking for time to obtain IRS data for only this star, our brightest source. We plan to obtain SL1 (7.4-14.5 microns) and SL2 (5.2-8.7 microns) spectroscopy only. We know the IRAC fluxes so our integration toies are well constrained and the spectral region covered by SL1, SL2 will yield sufficient S/N to differentiate between cool dust (rising BB like spectrum with PAH and other molecular features allowing us to determine dust size, temperature, and disk extent) and a T type dwarf showing characteristic spectral signatures and a falling Rayleigh-Jeans tail.

  13. Effect of marginal maternal zinc intake on zinc absorption and growth of 3-month-old infant rhesus monkeys

    SciTech Connect

    Loennerdal, B.K.; Keen, C.L.; Bell, J.G.; Golub, M.S.; Hendrickx, A.G.; Gershwin, M.E. )

    1990-09-01

    One compensatory mechanism for marginal zinc intake may be through an enhanced absorption of zinc. Such a compensatory mechanism could be of value to the neonate, as poor zinc nutriture during early life has severe consequences on growth and development. We studied the uptake of zinc by 3-month-old infant rhesus monkeys born to dams fed control diets 100 micrograms of zinc per gram of diet or zinc-restricted diets (4 micrograms of zinc per gram of diet). Zinc uptake/retention was studied by feeding 3-month-old infant monkeys that had fasted an infant formula containing zinc 65 by gavage. Whole body radioactivity was counted immediately after intubation and on days 10 and 17 after intubation. Regardless of dietary group, 65-zinc retention was high, ranging from 33% to 71% of the dose fed to the monkeys. There were no significant differences between the two dietary groups in the percentage of zinc retention at days 10 and 17. Independent of the dietary group, there was no correlation between plasma zinc and zinc absorption. A positive correlation was found between weight gain and zinc retention in the marginal zinc infants, while a negative correlation between weight gain and zinc retention was observed in the control infants. These observations suggest that the mechanisms underlying growth may be different in infants born to dams fed control vs marginal zinc diets.

  14. Prenatal exposure to polychlorinated biphenyls and their hydroxylated metabolites is associated with neurological functioning in 3-month-old infants.

    PubMed

    Berghuis, Sietske A; Soechitram, Shalini D; Sauer, Pieter J J; Bos, Arend F

    2014-12-01

    Polychlorinated biphenyls (PCBs) are environmental chemicals which are potentially toxic to the developing brain. Their hydroxylated metabolites (OH-PCBs) are suggested to be even more toxic. Knowledge about the health effects of prenatal OH-PCB exposure is limited. We aimed to determine whether prenatal background exposure to PCBs and OH-PCBs is associated with neurological functioning in 3-month-old boys and girls. In a Dutch observational cohort study, we measured 10 PCBs and 6 OH-PCBs in maternal blood samples of 98 pregnant women. We assessed their infants neurologically with Touwen examination at 3 months and calculated an Optimality Score (OS, range 0-53, low-high optimality). We calculated correlation coefficients between compound levels and OS. Subsequently, we tested whether levels were associated with specific clusters and whether levels differed between infants with "normal" (dysfunction on ≤1 cluster) and "non-optimal" development (dysfunction on ≥2 clusters). The mean OS was 48 (range 44-52). Higher exposure to PCB-146 correlated significantly with higher OS (r = 0.209; p = 0.039). In boys, higher exposure to 4-OH-PCB-107 correlated with lower OS (r = -0.305; p = 0.030). Higher exposure to 9 PCBs and the sum of all PCBs was associated with better visuomotor and/or better sensorimotor function. Infants classified as "non-optimal" (n = 36) had significantly lower prenatal exposure to 6 PCBs and the sum of all PCBs (p < 0.05) compared with infants classified as "normal" (n = 62). In conclusion, higher prenatal exposure to Dutch background PCB levels is associated with better neurological functioning in 3-month-old infants. Prenatal exposure to 4-OH-PCB-107 is associated with less optimal neurological functioning in boys.

  15. Estimating interevent time distributions from finite observation periods in communication networks

    NASA Astrophysics Data System (ADS)

    Kivelä, Mikko; Porter, Mason A.

    2015-11-01

    A diverse variety of processes—including recurrent disease episodes, neuron firing, and communication patterns among humans—can be described using interevent time (IET) distributions. Many such processes are ongoing, although event sequences are only available during a finite observation window. Because the observation time window is more likely to begin or end during long IETs than during short ones, the analysis of such data is susceptible to a bias induced by the finite observation period. In this paper, we illustrate how this length bias is born and how it can be corrected without assuming any particular shape for the IET distribution. To do this, we model event sequences using stationary renewal processes, and we formulate simple heuristics for determining the severity of the bias. To illustrate our results, we focus on the example of empirical communication networks, which are temporal networks that are constructed from communication events. The IET distributions of such systems guide efforts to build models of human behavior, and the variance of IETs is very important for estimating the spreading rate of information in networks of temporal interactions. We analyze several well-known data sets from the literature, and we find that the resulting bias can lead to systematic underestimates of the variance in the IET distributions and that correcting for the bias can lead to qualitatively different results for the tails of the IET distributions.

  16. Latitudinal variation of perturbation electric fields during magnetically disturbed periods - 1986 Sundial observations and model results

    NASA Technical Reports Server (NTRS)

    Fejer, B. G.; Spiro, R. W.; Wolf, R. A.; Foster, J. C.

    1990-01-01

    F-region incoherent scatter radar drift observations from Millstone Hill and Jicamarca, h-prime F observations from Huancayo, and high latitude ground-magnetometer measurements taken during the Sundial 1986 campaign are used to study the relationship between plasmaspheric electric field perturbations and high latitude currents during disturbed periods. The observations are in good agreement with numerical results from a Rice Covection Model run that involved a sharp increase in the polar cap potential drop followed by a subsequent decrease. The zonal disturbance electric field pattern is latitude independent, and the corresponding amplitudes change approximately as L exp n (where n is about 1.5). The meridional electric field patterns and amplitudes have larger latitudinal variations. The mid-, low, and equatorial electric fields from the Rice Convection Model are in good agreement with previous results from the semianalytic, Senior-Blanc (1987) model. Also discussed are three physical mechanisms (over-shielding, fossil winds, and magnetic reconfiguration) that contribute to the long lasting (1-2 h) equatorial zonal electric field perturbations associated with a sudden northward turning of the IMF. It is predicted that the penetration of high latitude electric fields to low latitudes should, in general, be closely related to the rate of motion of the shielding layer and the equatorward edge of the diffuse aurora.

  17. Estimating interevent time distributions from finite observation periods in communication networks.

    PubMed

    Kivelä, Mikko; Porter, Mason A

    2015-11-01

    A diverse variety of processes-including recurrent disease episodes, neuron firing, and communication patterns among humans-can be described using interevent time (IET) distributions. Many such processes are ongoing, although event sequences are only available during a finite observation window. Because the observation time window is more likely to begin or end during long IETs than during short ones, the analysis of such data is susceptible to a bias induced by the finite observation period. In this paper, we illustrate how this length bias is born and how it can be corrected without assuming any particular shape for the IET distribution. To do this, we model event sequences using stationary renewal processes, and we formulate simple heuristics for determining the severity of the bias. To illustrate our results, we focus on the example of empirical communication networks, which are temporal networks that are constructed from communication events. The IET distributions of such systems guide efforts to build models of human behavior, and the variance of IETs is very important for estimating the spreading rate of information in networks of temporal interactions. We analyze several well-known data sets from the literature, and we find that the resulting bias can lead to systematic underestimates of the variance in the IET distributions and that correcting for the bias can lead to qualitatively different results for the tails of the IET distributions.

  18. "Radiative Closure Studies for Clear Skies During the ARM 2003 Aerosol Intensive Observation Period"

    SciTech Connect

    J. J. Michalsky, G. P. Anderson, J. Barnard, J. Delamere, C. Gueymard, S. Kato, P. Kiedron, A. McComiskey, and P. Ricchiazzi

    2006-04-01

    The Department of Energy's Atmospheric Radiation Measurement (ARM) program sponsored a large intensive observation period (IOP) to study aerosol during the month of May 2003 around the Southern Great Plains (SGP) Climate Research Facility (CRF) in north central Oklahoma. Redundant measurements of aerosol optical properties were made using different techniques at the surface as well as in vertical profile with sensors aboard two aircraft. One of the principal motivations for this experiment was to resolve the disagreement between models and measurements of diffuse horizontal broadband shortwave irradiance at the surface, especially for modest aerosol loading. This paper focuses on using the redundant aerosol and radiation measurements during this IOP to compare direct beam and diffuse horizontal broadband shortwave irradiance measurements and models at the surface for a wide range of aerosol cases that occurred during 30 clear-sky periods on 13 days of May 2003. Models and measurements are compared over a large range of solar-zenith angles. Six different models are used to assess the relative agreement among them and the measurements. Better agreement than previously achieved appears to be the result of better specification of input parameters and better measurements of irradiances than in prior studies. Biases between modeled and measured direct irradiances are less than 1%, and biases between modeled and measured diffuse irradiances are less than 2%.

  19. Periodic behaviors in the observed vertical column abundances of atmospheric hydroxyl

    NASA Technical Reports Server (NTRS)

    Burnett, Elizabeth Beaver; Burnett, Clyde R.; Minschwaner, Kenneth R.

    1989-01-01

    The data base for the vertical column abundance of atmospheric hydroxyl (OH) for Fritz Peak Observatory, Colorado (40 N, 105 W), now extends from 1976 through 1988 and is composed of 8849 independent data sets, averaging about 15 percent uncertainty and 20-minute time resolution each. The dominant solar zenith angle (chi) dependence of the OH abundance is characterized by an empirical curve, N(88), which has been updated from N(82) to include all valid data from 1980 through 1988. The chi-dependence of the OH abundance has been, to a first order, removed from the data base by a normalization procedure in which each data point is divided by the N(88,AM) value for the corresponding solar zenith angle. The resulting normalized OH values may then be examined for other systematic effects, particularly for periodic variations. Observations have also been made at Boca Raton, Florida (26 N, 80 W) and at Truk, Federated States of Micronesia (7 N, 152 E). These data bases are much less extensive and, as such, are less amenable to analysis for periodic behaviors. Some comparisons with the Colorado data may be made, however.

  20. Observation of stimulated emission in an ultrashort-period nonsymmetric GaAs/AlAs superlattice

    SciTech Connect

    Litovchenko, V. G.; Korbutyak, D. V.; Bercha, A. I.; Kryuchenko, Yu. V.; Krylyuk, S. G.; Grahn, H. T.; Hey, R.; Ploog, K. H.

    2001-06-25

    Nonsymmetric short-period GaAs/AlAs superlattices, for which the well thickness is at least a factor of 2 larger than the barrier thickness, have been shown to exhibit a direct band gap for any well thickness. These superlattices are characterized by an enhanced intensity of the luminescence as compared to their symmetric indirect-gap counterparts with the same well width, and, thus, may be used as light-emitting devices, in particular, as low-threshold lasers in the red visible spectrum. This conjecture is supported by the observation of stimulated emission at T=80K for a GaAs/AlAs superlattice with six monolayers well and three monolayers barrier width. {copyright} 2001 American Institute of Physics.

  1. Cancer incidence among asbestos-exposed chemical industry workers: An extended observation period

    SciTech Connect

    Hilt, B.; Andersen, A.; Rosenberg, J.; Langard, S. )

    1991-01-01

    A previous study on the incidence of cancer in a cohort of 286 asbestos-exposed electrochemical industry workers observed from 1953 through 1980 has been extended with another 8 years of follow-up. The incidence of cancer was derived from the Cancer Registry of Norway, and the expected figures were calculated by a life table method. During the extended follow-up period from 1981 through 1988, among the cohort members there were 12 new cancer cases versus 14.2 expected (SIR 85, 95% CI 44-158). In a lightly exposed sub-cohort, the extended follow-up revealed 4 cases of lung cancer or pleural mesothelioma (ICD, 7th revision 162-163) versus 1.6 cases expected (SIR 256, 95% CI71-654). In a heavily exposed sub-cohort, the corresponding figures were 3 and 0.5 (SIR 588, 95% CI 118-1,725).

  2. Observation of Exchange Anisotropy in Single-Phase Layer-Structured Oxides with Long Periods

    PubMed Central

    Huang, Yan; Wang, Guopeng; Sun, Shujie; Wang, Jianlin; Peng, Ranran; Lin, Yue; Zhai, Xiaofang; Fu, Zhengping; Lu, Yalin

    2015-01-01

    A remarkable exchange bias effect arising from the temperature-dependent interaction among the ferromagnetic-like cluster glasses and antiferromagnetic regions was observed in a newly developed single-phase multiferroic compound of Bi10Fe6Ti3O30 which has a nine-layer Aurivillius structure. Inhomogeneous distribution of magnetic Fe ions inside this long-period layered structure was experimentally identified via the atomic level imaging. The results confirmed the presence of the short-range magnetic ordering (the cluster glassy state) and the canted antiferromagnetism, and then the direct interaction among them was further confirmed. Finding of this new single-phase material accompanying this remarkable exchange bias effect would be beneficial to both basic physics understanding and the potential device development. PMID:26487509

  3. Substorms observations over Apatity during geomagnetic storms in the period 2012 - 2016

    NASA Astrophysics Data System (ADS)

    Guineva, Veneta; Werner, Rolf; Despirak, Irina; Kozelov, Boris

    2016-07-01

    In this work we studied substorms, generated during enhanced geomagnetic activity in the period 2012 - 2016. Observations of the Multiscale Aurora Imaging Network (MAIN) in Apatity have been used. Solar wind and interplanetary magnetic field parameters were judged by the 1-min sampled OMNI data base. Substorm onset and further development were verified by the 10-s sampled data of IMAGE magnetometers and by data of the all-sky camera at Apatity. Subject of the study were substorms occurred during geomagnetic storms. The so-called "St. Patrick's day 2015 event" (17-21 March 2015), the events on 17-18 March 2013 and 7-17 March 2012 (a chain of events generated four consecutive storms) which were among the events of strongest geomagnetic activity during the current solar cycle 24, were part of the storms under consideration. The behavior of the substorms developed during different phases of the geomagnetic storms was discussed.

  4. Evaporation over land surfaces - First results from HAPEX-MOBILHY Special Observing Period

    NASA Technical Reports Server (NTRS)

    Andre, Jean-Claude; Goutorbe, Jean-Paul; Bessemoulin, Pierre; Perrier, Alain; Becker, Francois

    1988-01-01

    Preliminary results are presented from the May 7-July 15, 1986 Special Observing Period (SOP) of the HAPEX-MOBILHY program, which examines the hydrological budget and evaporation flux at the scale of a 10,000 sq km GCM grid square to determine soil moisture, surface-energy budgets, and surface hydrology. The SOP used two highly instrumented remote sensing aircraft to obtain detailed measurements of atmospheric fluxes and surface properties. It is noted that the measurements are reliable at spatially local and short time scales, as well as on the monthly time scale. The data base obtained may be used in parametrization schemes against which land-surface water budgets can be tested.

  5. Observations of deep long-period (DLP) seismic events beneath Aleutian arc volcanoes; 1989-2002

    USGS Publications Warehouse

    Power, J.A.; Stihler, S.D.; White, R.A.; Moran, S.C.

    2004-01-01

    Between October 12, 1989 and December 31, 2002, the Alaska Volcano Observatory (AVO) located 162 deep long-period (DLP) events beneath 11 volcanic centers in the Aleutian arc. These events generally occur at mid- to lower-crustal depths (10-45 km) and are characterized by emergent phases, extended codas, and a strong spectral peak between 1.0 and 3.0 Hz. Observed wave velocities and particle motions indicate that the dominant phases are P- and S-waves. DLP epicenters often extend over broad areas (5-20 km) surrounding the active volcanoes. The average reduced displacement of Aleutian DLPs is 26.5 cm2 and the largest event has a reduced displacement of 589 cm2 (or ML2.5). Aleutian DLP events occur both as solitary events and as sequences of events with several occurring over a period of 1-30 min. Within the sequences, individual DLPs are often separated by lower-amplitude volcanic tremor with a similar spectral character. Occasionally, volcano-tectonic earthquakes that locate at similar depths are contained within the DLP sequences.At most, Aleutian volcanoes DLPs appear to loosely surround the main volcanic vent and occur as part of background seismicity. A likely explanation is that they reflect a relatively steady-state process of magma ascent over broad areas in the lower and middle portions of the crust. At Mount Spurr, DLP seismicity was initiated by the 1992 eruptions and then slowly declined until 1997. At Shishaldin Volcano, a short-lived increase in DLP seismicity occurred about 10 months prior to the April 19, 1999 eruption. These observations suggest a link between eruptive activity and magma flux in the mid- to lower-crust and uppermost mantle.

  6. Observing and Modeling the Optical Counterparts of Short-Period Binary Millisecond Pulsars

    NASA Astrophysics Data System (ADS)

    Schroeder, Joshua

    In this dissertation, I explore the subject of short-period binary millisecond pulsars discovered by the Fermi Gamma-ray Space Telescope and radio follow-up teams, and present observations of fields containing eight recently discovered short-period (Porb < 1 d) binary millisecond pulsars using the telescopes at MDM Observatory. The goal of these observations was to detect the optical counterparts of the binaries and, for the best-suited counterparts detected, to observe the photometric variation of the companion that happens over the course of the orbit in various filters. The hope was to then use the light curves to model the systems and obtain constraints on the mass of the neutron stars which are likely to be some of the most massive neutron stars in the galaxy. Optical counterparts to four of these systems are detected, one of which, PSR J2214+3000, is a novel detection. Additionally, I present the fully orbital phase-resolved B, V , and R light curves of the optical counterparts to two objects, PSR J1810+1744 and PSR J2215+5135, for which I employ the ELC model of Orosz & Hauschildt (2000) to measure the unknown system parameters. For PSR J1810+1744 I find that the system parameters cannot be fit even assuming that 100% of the spin-down luminosity of the pulsar is irradiating the secondary, and so radial velocity measurements of this object will be required for the complete solution. However, PSR J2215+5135 exhibits light curves that are extremely well constrained using the ELC model and we find that the mass of the neutron star is constrained by these and the radio observations to be MNS > 1.75 solar masses; at the 3-sigma level. I also find a discrepancy between the model temperature and the measured colors of this object which I interpret as possible evidence for an additional high-temperature source such as a quiescent disk. Given this and the fact that PSR J2215+5135 contains a relatively high mass companion (Mc > 0.1 solar masses), I propose that similar

  7. Changes in ENACW observed in the Bay of Biscay over the period 1975-2010

    NASA Astrophysics Data System (ADS)

    Gómez-Gesteira, M.; deCastro, M.; Santos, F.; Álvarez, I.; Costoya, X.

    2013-08-01

    Trends in Eastern North Atlantic Central Water (ENACW) were calculated in the Bay of Biscay over the period 1975-2010 using the Simple Ocean Data Assimilation (SODA) package. This approach, which reanalyzes data from different sources, allows obtaining information beneath the sea surface on a fine 0.5°×0.5° grid with 40 vertical layers, providing a complete view of the different hydrographic processes in the area. ENACW, which was associated to salinity and temperature values corresponding to the density interval 27.0-27.2 kg m-3, was observed to warm and salinificate in most of the area at a maximum rate of 0.11 °C per decade and 0.03 psu per decade, respectively. Trends are more intense in the middle part of the Bay and near the northeastern boundary. The origin of the changes in ENACW observed inside the Bay of Biscay is not due to local effects. Actually, trends seem to be related to changes in the subpolar mode of ENACW (ENACWsp), affecting a wider North Atlantic area. The highest trends (0.3 °C per decade in temperature and 0.05 psu per decade in salinity) were observed north of the bay, especially at the shallow area that stretches from Brest to Ireland, which is characterized by deep winter mixing. The dependence of changes in ENACW on the two main modes of variability over the North Atlantic (NAO and EA) was also analyzed. Trends in salinity and temperature showed to be consistent with changes observed in EA. In addition, air temperature and precipitation minus evaporation (P-E) balance showed to contribute to warming and salinification of ENACW.

  8. Pivotal Response Treatment Parent Training for Autism: Findings from a 3-Month Follow-Up Evaluation.

    PubMed

    Gengoux, Grace W; Berquist, Kari L; Salzman, Emma; Schapp, Salena; Phillips, Jennifer M; Frazier, Thomas W; Minjarez, Mendy B; Hardan, Antonio Y

    2015-09-01

    This study's objective was to assess maintenance of treatment effects 3 months after completion of a 12-week Pivotal Response Treatment (PRT) parent education group. Families who completed the active treatment (N = 23) were followed for an additional 12 weeks to measure changes in language and cognitive skills. Results indicated a significant improvement in frequency of functional utterances, with maintenance at 3-month follow-up [F(2, 21): 5.9, p = .009]. Children also made significant gains on the Vineland Communication Domain Standard Score [F(2, 12):11.74, p = .001] and the Mullen Scales of Early Learning Composite score [F(1, 20) = 5.43, p = .03]. These results suggest that a brief PRT parent group intervention can lead to improvements in language and cognitive functioning that are maintained 12 weeks post treatment.

  9. Schistosoma mansoni Infection 3 Months after Praziquantel Therapy Among Farmers in Qalyub, Egypt

    DTIC Science & Technology

    1993-05-01

    REPORT TYPE AND DATES COVERED 1993 I - 4.-11I-C- A/" SUBDIIILE 5. FUNDING NUMBERS Schistosoma mansoni Infection 3 Months after Praziquantel Therapy PE...region of the Nile Delta. Treatment with praziquantel at the recommended dose 40 mg/kg body weight in a single oral dose was taken by 668 (87%) of...to evaluate optimal dosage of praziquantel and sequential treatment schedules to achieve effective control of transmission are indicated. 14. SUBJECT

  10. The Relationship between Gentle Tactile Stimulation on the Fetus and Its Temperament 3 Months after Birth

    PubMed Central

    Wang, Zhe-Wei; Hua, Jing; Xu, Yu-Hong

    2015-01-01

    Objective. The aim of this study was to evaluate the effect of gentle tactile stimulation on the fetus in its temperament 3 months after birth. Method. A total of 302 mother-3-month-infant dyads enrolled the retrospective cohort study. 76 mothers had regular gentle tactile stimulation on the fetus in their pregnancy; 62 mothers had irregular tactile stimulation on the fetus, and the rest of 164 mothers who had no tactile stimulation served as nonexposure group. Temperament was assessed using the EITS (a nine-dimensional scale of temperament). Results. Significant difference in temperament type was found among infants in 3 groups at 3 months of age. In the regular practice group, the babies with easy type temperament accounted for 73.7%, which was higher than that in irregular practice group (53.2%, P = 0.012) and that in the control group (42.1%, P < 0.001). Compared to infants in no practice group, the infants who had received regular gentle tactile stimulation before birth were lower in negative mood (P = 0.047) while higher in adaptability (P < 0.001), approach (P = 0.001), and persistence (P = 0.001), respectively. Conclusion. Regular gentle tactile stimulation on fetus may promote the formation of easy type infant temperament. PMID:26180374

  11. Painful Memories: Reliability of Pain Intensity Recall at 3 Months in Senior Patients

    PubMed Central

    Lee, Jacques S.; Griffith, Lauren E.; Paquet, Jean; Chauny, Jean-Marc

    2017-01-01

    Background. Validity of pain recall is questioned in research. Objective. To evaluate the reliability of pain intensity recall for seniors in an emergency department (ED). Methods. This study was part of a prospective multicenter project for seniors (≥65 years old) treated in an ED for minor traumatic injury. Pain intensity (0–10 numerical rating scale) was evaluated at the initial ED visit, at one week (baseline), and 3 months. At three months, patients were asked to recall the pain intensity they had at baseline. Results. 482 patients were interviewed (mean age 76.6 years, SD ± 7.3) and 72.8% were female. Intraclass correlation coefficient between pain at baseline and its recall was 0.24 (95% CI: 0.14–0.33). Senior patients tended to overestimate their pain intensity by a mean of 1.2 (95% CI: 0.9–1.5) units. A stepwise multiple regression analysis showed that the variance of baseline pain recall at 3 months was explained by pain at ED visit (11%), pain at 3 months (7%), and pain at baseline (2%). Conclusion. The accuracy of pain intensity recall after three months is poor in seniors and seems to be influenced by the pain experienced at the time of injury. PMID:28260963

  12. Observation of Geometric Parametric Instability Induced by the Periodic Spatial Self-Imaging of Multimode Waves

    NASA Astrophysics Data System (ADS)

    Krupa, Katarzyna; Tonello, Alessandro; Barthélémy, Alain; Couderc, Vincent; Shalaby, Badr Mohamed; Bendahmane, Abdelkrim; Millot, Guy; Wabnitz, Stefan

    2016-05-01

    Spatiotemporal mode coupling in highly multimode physical systems permits new routes for exploring complex instabilities and forming coherent wave structures. We present here the first experimental demonstration of multiple geometric parametric instability sidebands, generated in the frequency domain through resonant space-time coupling, owing to the natural periodic spatial self-imaging of a multimode quasi-continuous-wave beam in a standard graded-index multimode fiber. The input beam was launched in the fiber by means of an amplified microchip laser emitting sub-ns pulses at 1064 nm. The experimentally observed frequency spacing among sidebands agrees well with analytical predictions and numerical simulations. The first-order peaks are located at the considerably large detuning of 123.5 THz from the pump. These results open the remarkable possibility to convert a near-infrared laser directly into a broad spectral range spanning visible and infrared wavelengths, by means of a single resonant parametric nonlinear effect occurring in the normal dispersion regime. As further evidence of our strong space-time coupling regime, we observed the striking effect that all of the different sideband peaks were carried by a well-defined and stable bell-shaped spatial profile.

  13. In Hospital and 3-Month Mortality and Functional Recovery Rate in Patients Treated for Hip Fracture by a Multidisciplinary Team

    PubMed Central

    Rostagno, Carlo; Buzzi, Roberto; Campanacci, Domenico; Boccacini, Alberto; Cartei, Alessandro; Virgili, Gianni; Belardinelli, Andrea; Matarrese, Daniela; Ungar, Andrea; Rafanelli, Martina; Gusinu, Roberto; Marchionni, Niccolò

    2016-01-01

    Objectives Medical comorbidities affect outcome in elderly patients with hip fracture. This study was designed to preliminarily evaluate the usefulness of a hip-fracture unit led by an internal medicine specialist. Methods In-hospital and 3-month outcomes in patients with hip fracture were prospectively evaluated in 121 consecutive patients assessed before and followed after surgery by a multidisciplinary team led by internal medicine specialist; 337 consecutive patients were recalled from ICD-9 discharge records and considered for comparison regarding in-hospital mortality. Results In the intervention period, patients treated within 48 hours were 54% vs. 26% in the historical cohort (P<0.0001). In-hospital mortality remained stable at about 2.3 per 1000 person-days. At 3 months, 10.3% of discharged patients had died, though less than 8% of patients developed postoperative complications (mainly pneumonia and respiratory failure). The presence of more than 2 major comorbidities and the loss of 3 or more BADL were independent predictors of death. 50/105 patients recovered previous functional capacity, but no independent predictor of functional recovery could be identified. Mean length of hospital stay significantly decreased in comparison to the historical cohort (13.6± 4.7 vs 17 ± 5 days, p = 0.0001). Combined end-point of mortality and length of hospitalization < 12 days was significantly lower in study period (27 vs 34%, p <0.0132). Conclusions Identification and stabilization of concomitant clinical problems by internal medicine specialists may safely decrease time to surgery in frail subjects with hip fracture. Moreover, integrated perioperative clinical management may shorten hospital stay with no apparent increase in in-hospital mortality and ultimately improve the outcome. These results are to be confirmed by a larger study presently ongoing at our institution. PMID:27389193

  14. Comparative in vitro release and clinical pharmacokinetics of leuprolide from Luphere 3M Depot, a 3-month release formulation of leuprolide acetate.

    PubMed

    Park, Sunghoon; Kim, Dong-Hwan; Kim, Yoon; Park, Jeong Hwa; Lee, MinSeok; Song, Im-Sook; Shim, Chang-Koo

    2017-03-01

    A 3-month depot formulation of leuprolide acetate (Luphere 3M Depot) with a mean microsphere diameter of 22.3 μm was prepared aseptically by spray-drying glacial acetic acid solution of the drug and polylactic acid, and lyophilization in a d-mannitol solution. The encapsulation efficiency and loading content of the drug in the Luphere 3M Depot were 94.7% and 9.92% (w/w), respectively. The in vitro release of leuprolide from the depot was substantially delayed and the release profile was similar to that of Lucrin Depot (Abbott Korea, Korea). The safety and pharmacokinetics of leuprolide were investigated over a period of 42 days in 20 prostate cancer patients following a subcutaneous injection of Luphere 3M or Lucrin Depot suspensions (leuprolide acetate dose of 11.25 mg) in a multi-center, randomized, single dose, parallel study. Both formulations were well tolerated by the patients and no serious adverse effects were observed during and after the study. No significant differences were observed in the maximum serum concentration (Cmax) and area under the curve (AUClast) of leuprolide between the two formulations. The results suggest comparable safety and efficacy profiles of Luphere 3M Depot and Lucrin Depot in clinical situations.

  15. Concentric waves and short-period oscillations observed in the ionosphere after the 2013 Moore EF5 tornado

    NASA Astrophysics Data System (ADS)

    Nishioka, Michi; Tsugawa, Takuya; Kubota, Minoru; Ishii, Mamoru

    2013-11-01

    We detected clear concentric waves and short-period oscillations in the ionosphere after an Enhanced Fujita scale (EF)5 tornado hit Moore, Oklahoma, U.S., on 20 May 2013 using dense wide-coverage ionospheric total electron content (TEC) observations in North America. These concentric waves were nondispersive, with a horizontal wavelength of ~120 km and a period of ~13 min. They were observed for more than 7 h throughout North America. TEC oscillations with a period of ~4 min were also observed to the south of Moore for more than 8 h. A comparison between the TEC observations and infrared cloud image from the GOES satellite indicates that the concentric waves and short-period oscillations are caused by supercell-induced atmospheric gravity waves and acoustic resonances, respectively. This observational result provides the first clear evidence of a severe meteorological event causing atmospheric waves propagating upward in the upper atmosphere and reaching the ionosphere.

  16. Wave-Wave Interactions in the Stratosphere: Observations during Quiet and Active Wintertime Periods.

    NASA Astrophysics Data System (ADS)

    Smith, Anne K.; Gille, John C.; Lyjak, Lawrence V.

    1984-02-01

    Using satellite data from the Nimbus 7 LIMS instrument, a previous study by Smith showed that interactions among planetary waves 1, 2 and 3 in the stratosphere were significant during January 1979. That month was characterized by an exceptionally large wave 1 amplitude in the stratosphere. The present study extends the analysis to the period November 1978-March 1979 to determine the conditions under which wave-wave interactions have a significant effect on variations in wave activity and on wave-mean flow interactions. A quantitative measure of how wave-wave interactions affect the wave activity of zonal waves 1 and 2 is obtained from the potential enstrophy budget.The results demonstrate that the relative importance of wave-wave versus wave-mean flow interactions depends on the magnitude of the eddy mean wind and potential vorticity relative to the zonal means. When the zonal mean wind is weak, a relatively small amplitude wave tends to behave nonlinearly, whereas when the mean wind is strong, only large amplitude waves are significantly nonlinear. In the 1978-79 winter, the zonal mean wind was weaker and wave-wave interactions were more important in middle and late winter than during November-December.Further evidence is presented that the vacillation between waves 1 and 2, which has been observed in the winter stratosphere of both hemispheres, is as strongly influenced by wave-wave interactions in the stratosphere as by variations in the forcing from the troposphere.

  17. Observations of long-period oscillations of the solar active regions in the visible and UV spectral intervals

    NASA Astrophysics Data System (ADS)

    Tlatov, A. G.; Dormidontov, D. V.; Chernov, Ya. O.

    2016-12-01

    The variation of intensity in spectral line wings, which was obtained from observations of the patrol telescope at the Kislovodsk Mountain Astronomical Station of the Pulkovo Observatory, Russian Academy of Science (KMAS) and the Interface Region Imaging Spectrograph (IRIS) space observatory, are considered. A series of observations lasting a few hours near the solar active regions, in which both short- and longperiod oscillations were observed simultaneously during 2014-2015, are analyzed. It is found out that oscillations with a period of 3-5 min can exist at one time and in one place with oscillations with a period of about 100 min. The amplitude of long-period oscillations can be comparable with that for short-period oscillations. The conditions for excitation of the wave processes are considered. Oscillations with a period of 100 min have a weak dependence on the area of the active region.

  18. Septic Arthritis in Infants Younger Than 3 Months: A Retrospective Review.

    PubMed

    Bono, Kenneth T; Samora, Julie Balch; Klingele, Kevin E

    2015-09-01

    Septic arthritis in infants is rare and can be difficult to diagnose. This study reviewed a series of patients younger than 3 months to identify factors that may assist in early diagnosis and treatment. A query of records at a large Midwestern pediatric hospital (1994-2010) was performed to identify all patients younger than 3 months at the time of diagnosis. Analysis included birth history, joint involvement, physical examination findings, laboratory results, imaging results, method of treatment, and outcome. In 14 cases (11 boys, 3 girls; mean age at diagnosis, 42.2 days), complete records were available for review. Involved joints included the knee, hip, and shoulder. The most common findings on physical examination were decreased range of motion (100%), tenderness (100%), and swelling (71.4%). Mean temperature was 38.5°C. Mean white blood cell count was 18.5 K/µL, mean erythrocyte sedimentation rate was 48.9 mm/h, and mean C-reactive protein level was 6.1 mg/dL. More than half (57.1%) of joint aspirates grew positive cultures, and 41.7% of blood cultures had positive results. Causative organisms were group B streptococcus, methicillin-sensitive Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Salmonella enterica, and Candida albicans. The most common physical examination findings in infants younger than 3 months with septic arthritis include tenderness, decreased range of motion, and swelling. White blood cell count, C-reactive protein level, and erythrocyte sedimentation rate are likely to be elevated, but these findings should be used in combination with findings on physical examination and radiographic studies to aid in diagnosis.

  19. Posttraumatic reactions among injured children and their caregivers 3 months after the terrorist attack in Beslan.

    PubMed

    Scrimin, Sara; Axia, Giovanna; Capello, Fabia; Moscardino, Ughetta; Steinberg, Alan M; Pynoos, Robert S

    2006-03-30

    This report describes symptoms of posttraumatic stress disorder (PTSD) among a group of Beslan's children (N=22) and their primary caregivers (N=20) 3 months after the children had been taken hostage in their school by a group of terrorists. Attention and memory were also measured. Children and their caretakers showed high levels of ongoing PTSD symptoms. Children also showed difficulties in sustaining attention and in short-term memory (digit span). These scores strongly indicate the need for appropriate interventions and ongoing monitoring of course of recovery.

  20. Solitary Myofibroma of the Bladder Trigone in a 3-Month-Old Patient: First Case Report

    PubMed Central

    Pensabene, Marco; Siracusa, Fortunato; Rodolico, Vito; Li Voti, Giuseppe; Zambaiti, Elisa; Cimador, Marcello

    2016-01-01

    Visceral solitary myofibromas are uncommon in childhood. We report a case of a solitary asymptomatic visceral myofibroma of the bladder trigone occurring in a 3-month-old boy. Once malignancies were ruled out by cystoscopy, radical excision was performed in order to avoid any potential impairment of bladder dynamic. Postoperative course was uneventful and patient was discharged on day 3 after surgery. After 36 months of follow-up, the patient is toilet-trained and remains well; bladder function is normal. PMID:27242942

  1. Osteofibrous dysplasia-like adamantinoma in a 3-month-old male infant: a case report.

    PubMed

    Buldu, Halil; Centel, Tuncay; Kırımlıoğlu, Hale; Dirik, Yalın

    2015-01-01

    We report a case of a very rarely seen osteofibrous dysplasia-like adamantinoma (OFDLA) of the lower leg in a 3-month-old male infant, making it the youngest case in the literature. OFDLA is typically regarded as a benign lesion; however, due to its convertibility into classical adamantinoma, it is recommended to evaluate it as a pre-malignant lesion. After OFDLA diagnosis with biopsy, our case underwent surgical resection and reconstruction with a large allograft. Patient experienced good outcomes and did not experience any local relapse in the 3-year follow-up.

  2. IS COMPTON COOLING SUFFICIENT TO EXPLAIN EVOLUTION OF OBSERVED QUASI-PERIODIC OSCILLATIONS IN OUTBURST SOURCES?

    SciTech Connect

    Mondal, Santanu; Chakrabarti, Sandip K.; Debnath, Dipak E-mail: chakraba@bose.res.in

    2015-01-01

    In outburst sources, quasi-periodic oscillation (QPO) frequency is known to evolve in a certain way: in the rising phase, it monotonically goes up until a soft intermediate state is achieved. In the propagating oscillatory shock model, oscillation of the Compton cloud is thought to cause QPOs. Thus, in order to increase QPO frequency, the Compton cloud must collapse steadily in the rising phase. In decline phases, the exact opposite should be true. We investigate cause of this evolution of the Compton cloud. The same viscosity parameter that increases the Keplerian disk rate also moves the inner edge of the Keplerian component, thereby reducing the size of the Compton cloud and reducing the cooling timescale. We show that cooling of the Compton cloud by inverse Comptonization is enough for it to collapse sufficiently so as to explain the QPO evolution. In the two-component advective flow configuration of Chakrabarti-Titarchuk, centrifugal force-induced shock represents the boundary of the Compton cloud. We take the rising phase of 2010 outburst of Galactic black hole candidate H 1743-322 and find an estimation of variation of the α parameter of the sub-Keplerian flow to be monotonically rising from 0.0001 to 0.02, well within the range suggested by magnetorotational instability. We also estimate the inward velocity of the Compton cloud to be a few meters per second, which is comparable to what is found in several earlier studies of our group by empirically fitting the shock locations with the time of observations.

  3. Emergence of Functional Flexibility in Infant Vocalizations of the First 3 Months

    PubMed Central

    Jhang, Yuna; Oller, D. Kimbrough

    2017-01-01

    Functional flexibility, as manifest in the use of any word or sentence to express different affective valences on different occasions, is required in linguistic communication and can be said to be an infrastructural property of language. Early infant vocalizations (protophones), believed to be precursors to speech, occur in the first month and are functionally different from non-speech-like signals (e.g., cries and laughs). Oller et al. (2013) showed that infants by 3 months used three different protophone types with a full range of affect as manifest in facial expression, from positive to neutral to negative. These differences in affect were also shown to correspond to different illocutionary functions, unlike fixed signals, or vegetative sounds, which showed functional rigidity. The present study investigated whether infants show functional flexibility in protophones even earlier than the ages studied by Oller et al. (2013). Data were obtained from 6 infants across the first 3 months. Results showed that as early as the first month, infant protophones were already accompanied by variable facial affect valences and continued to be affectively flexible at the later ages. The present study thus documents the very early emergence of an infrastructural property of human communication. PMID:28392770

  4. Neutrophil-To-Lymphocyte Ratio Predicts 3-Month Outcome of Acute Ischemic Stroke.

    PubMed

    Qun, Sen; Tang, Yan; Sun, Jing; Liu, Zhaoxia; Wu, Juncang; Zhang, Ji; Guo, Jidong; Xu, Zhiqiang; Zhang, Dan; Chen, Zhengxu; Hu, Fuyong; Xu, Xingshun; Ge, Wei

    2017-04-01

    Increasing evidences have demonstrated that inflammation is involved in the mechanisms of acute ischemic stroke (AIS). As an important and easy-to-measure inflammatory marker, neutrophil-to-lymphocyte ratio (NLR) shows a high association with mortality in patients with stroke in recent studies. In this study, we evaluated the prognostic role of NLR in patients with AIS. One hundred forty-three patients with AIS were enrolled. Clinical data were collected and the NLR was calculated from the admission blood work. The patients were followed up for 3 months after stroke onset. The occurrence of death and the major disability at 3 months after onset were end points in this study. Modified Rankin Scale score ≥3 was considered as poor outcome. In this study, 75 patients (52%) had poor outcome. We used binary logistic regression model to evaluate risk factor for poor outcome of AIS and found that the NLR was independently associated with the poor outcome of 3 months (P < 0.001). The optimal cutoff value for NLR as a predictor for 3-month outcome was 2.995. Therefore, in our study, high NLRs inversely predicted 3-month outcome in patients with AIS.

  5. Severe Kawasaki disease in a 3-month-old patient: a case report

    PubMed Central

    2013-01-01

    Background Kawasaki disease is a multi-system vasculitis which usually occurs in children under 5 years of age. In infants under three months of age, it is very rare and usually associated with a high incidence of incomplete or atypical forms, often unresponsive to treatment. This condition increases the risk of cardiovascular complications such as coronary artery aneurysms. Case presentation We describe a 3-month-old infant who developed early and severe aneurysms in three coronary arteries despite a timely administration of intravenous immunoglobulins, followed by three days of intravenous methylprednisolone. Conclusion This case report underlines that the development of coronary artery aneurysm correlates with a delayed diagnosis and treatment, incomplete or atypical forms of the disease, and additionally the severity of clinical presentation, especially in cases of very young infants below 3 months of age. Our case is notable because of the very young age of the patient, the severity of clinical presentation with an early development of coronary artery aneurysms and the unresponsiveness to the therapy. PMID:24294914

  6. A randomized controlled trial of brain training with non-action video games in older adults: results of the 3-month follow-up

    PubMed Central

    Ballesteros, Soledad; Mayas, Julia; Prieto, Antonio; Toril, Pilar; Pita, Carmen; Laura, Ponce de León; Reales, José M.; Waterworth, John A.

    2015-01-01

    This randomized controlled study (ClinicalTrials.gov NCT02007616) investigated the maintenance of training effects of 20 1-hr non-action video game training sessions with selected games from a commercial package on several age-declining cognitive functions and subjective wellbeing after a 3-month no-contact period. Two groups of cognitively normal older adults participated in both the post-training (posttest) and the present follow-up study, the experimental group who received training and the control group who attended several meetings with the research team during the study but did not receive training. Groups were similar at baseline on demographics, vocabulary, global cognition, and depression status. Significant improvements in the trained group, and no variation in the control group had been previously found at posttest, in processing speed, attention and visual recognition memory, as well as in two dimensions of subjective wellbeing. In the current study, improvement from baseline to 3 months follow-up was found only in wellbeing (Affection and Assertivity dimensions) in the trained group whereas there was no change in the control group. Previous significant improvements in processing speed, attention and spatial memory become non-significant after the 3-month interval. Training older adults with non-action video games enhanced aspects of cognition just after training but this effect disappeared after a 3-month no-contact follow-up period. Cognitive plasticity can be induced in older adults by training, but to maintain the benefits periodic boosting sessions would be necessary. PMID:25926790

  7. An assessment of the FGGE satellite observing system during SOP-1. [Special Observing Period in First GARP Global Experiment

    NASA Technical Reports Server (NTRS)

    Halem, M.; Kalnay, E.; Baker, W. E.; Atlas, R.

    1982-01-01

    The sensitivity of a Goddard Laboratory for Atmospheric Sciences global objective analysis cycle to the addition of FGGE level II-b data is assessed. The GOAS system comprises a predictive continuity provided by a model first-guess forecast integrated from a previous forecast and updated by data gathered in the interim. FGGE data originated in the Jan.-Mar. 1979 period and were acquired by rawinsondes, pilot balloons, surface stations, satellites, ships, and drifting buoys deployed during SOP-1. Focussing on 2-5 and 8-day forecasts, comparisons were made of the 6 hr forecast error at the 300 mb height in three experiments using all, no-satellite (NOSAT), and without rawinsondes or pilot balloons modes. Larger errors occurred in the case of NOSAT, while significant corrections to the GOAS predictions were noted using all the FGGE data. It was concluded that all forecasts were improved by inclusion of full FGGE data sets, including forecasting beyond one week.

  8. Simultaneous observations of periodic non-Io decametric radio emission by ground radio telescope URAN-2 and STEREO/WAVES

    NASA Astrophysics Data System (ADS)

    Panchenko, M.; Brazhenko, A. I.; Rucker, H. O.; Frantzusenko, A.; Shaposhnikov, V. E.; Konovalenko, A. A.

    2013-09-01

    Periodic bursts of the non-Io component of Jovian decametric radio emission (non-Io DAM) is observed as (1) series of arc-like radio bursts with negative frequency drift which reoccur with 1.5% longer period than the Jovian magnetosphere rotation rate, (2) series of bursts with positive frequency drift which reoccur with Jupiter's rotation period and (3) periodic non-arc like radio features [1, 2]. These bursts are typically detected during several Jupiter rotations in decametric frequency range from 4 MHz to 12 - 16 MHz between 300° and 60° of CML. We present simultaneous observations of the periodic non-Io controlled DAM performed by the WAVES radio experiment onboard the two STEREO spacecraft and the groundbased radio telescope URAN-2 (Poltava, Ukraine) operated in the decametric frequency range. URAN-2 with an effective area of about 30000 m2 consists of 512 broadband crossed dipoles and equipped with the high performance digital radio spectrometer with polarization measurement capability. During the observation campaign Sep., 2012 - Apr., 2013 URAN-2 recorded a large amount of Jovian DAM events with the high time-frequency resolution (4 kHz - 100 ms) in a frequency range 8-32 MHz. In the same time the two spatially separated STEREO spacecraft was able to observe DAM in the frequency range up to 16 MHz. The first analysis of the acquired stereoscopic observations is presented. In particular, we show one episode when the periodic non-arc DAM was recorded together with long lasting Jovian narrow band (NB) emissions. These NB emission was observed at the high frequency cutoff of DAM and can be interpreted as propagation of the decametric radiation in the Jovian ionosphere [3]. We discuss the possible relations between the observed NB events and the periodic non-Io controlled Jovian decametric radio emission.

  9. Parental Relationship with Twins from Pregnancy to 3 Months: The Relation Among Parenting Stress, Infant Temperament, and Well-Being.

    PubMed

    Prino, Laura E; Rollè, Luca; Sechi, Cristina; Patteri, Luciana; Ambrosoli, Anna; Caldarera, Angela M; Gerino, Eva; Brustia, Piera

    2016-01-01

    Objective: The transition to parenthood, from pregnancy to postpartum period, is a critical process, particularly for couples expecting twins. There is very little literature regarding the links between anxiety, depression, dyadic adjustment, parental stress, and infant temperament spanning from pregnancy to postpartum. This study has two aims: first, to examine whether mothers' and fathers' anxiety, depression, and dyadic adjustment, assessed at the sixth month of pregnancy and 3 months postpartum, are associated with infants' negative affectivity (NA) and parenting stress; second, to examine whether there is any difference between fathers' and mothers' levels of parenting stress and perception of the twins' temperament, as well as to evaluate, separately for mothers and fathers, whether the levels of parenting stress and perception of child temperament differ for each twin. Method: The study participants were 58 parents (29 couples) and their healthy 58 twin babies (51.7% boys, 48.3% girls). Mothers' ages ranged from 30 to 44 years, (MAge = 36.3 years, SD = 3.2 years), and fathers' ages ranged from 32 to 52 years, (MAge = 38.2 years, SD = 4.4 years). The parents, during the pregnancy period and 3 months after delivery, filled out the Edinburgh Postnatal Depression Scale, the State-Trait Anxiety Inventory, and the Dyadic Adjustment Scale. Three months after delivery they also filled out the Parenting Stress Index-Short Form and the Infant Behavior Questionnaire Revised. Results: The analyses showed a significant correlation between parental anxiety/depression symptoms and infants' NA and parenting stress (in both mothers and fathers). Moreover, compared to fathers, mothers reported higher scores on specific dimensions of the infants' NA, [t(28) = -2.62 and p < 0.05; t(28) = 2.09 and p < 0.05], and parenting stress, [t(28) = 2.19 and p < 0.05; t(28) = 2.23 and p < 0.05], but only for Twin 2. Finally, the results showed that mothers' perceptions of child temperament

  10. Parental Relationship with Twins from Pregnancy to 3 Months: The Relation Among Parenting Stress, Infant Temperament, and Well-Being

    PubMed Central

    Prino, Laura E.; Rollè, Luca; Sechi, Cristina; Patteri, Luciana; Ambrosoli, Anna; Caldarera, Angela M.; Gerino, Eva; Brustia, Piera

    2016-01-01

    Objective: The transition to parenthood, from pregnancy to postpartum period, is a critical process, particularly for couples expecting twins. There is very little literature regarding the links between anxiety, depression, dyadic adjustment, parental stress, and infant temperament spanning from pregnancy to postpartum. This study has two aims: first, to examine whether mothers’ and fathers’ anxiety, depression, and dyadic adjustment, assessed at the sixth month of pregnancy and 3 months postpartum, are associated with infants’ negative affectivity (NA) and parenting stress; second, to examine whether there is any difference between fathers’ and mothers’ levels of parenting stress and perception of the twins’ temperament, as well as to evaluate, separately for mothers and fathers, whether the levels of parenting stress and perception of child temperament differ for each twin. Method: The study participants were 58 parents (29 couples) and their healthy 58 twin babies (51.7% boys, 48.3% girls). Mothers’ ages ranged from 30 to 44 years, (MAge = 36.3 years, SD = 3.2 years), and fathers’ ages ranged from 32 to 52 years, (MAge = 38.2 years, SD = 4.4 years). The parents, during the pregnancy period and 3 months after delivery, filled out the Edinburgh Postnatal Depression Scale, the State-Trait Anxiety Inventory, and the Dyadic Adjustment Scale. Three months after delivery they also filled out the Parenting Stress Index—Short Form and the Infant Behavior Questionnaire Revised. Results: The analyses showed a significant correlation between parental anxiety/depression symptoms and infants’ NA and parenting stress (in both mothers and fathers). Moreover, compared to fathers, mothers reported higher scores on specific dimensions of the infants’ NA, [t(28) = -2.62 and p < 0.05; t(28) = 2.09 and p < 0.05], and parenting stress, [t(28) = 2.19 and p < 0.05; t(28) = 2.23 and p < 0.05], but only for Twin 2. Finally, the results showed that mothers

  11. Holoprosencephaly and diabetes insipidus in a 3-month-old infant.

    PubMed

    Kourti, Maria; Pavlou, Evaggelos; Rousso, Israel; Economou, Ippolyti; Athanassiadou, Fani

    2008-01-01

    Holoprosencephaly is a developmental defect caused by incomplete cleavage of the embryonic forebrain structures during early embryogenesis. We describe a 3-month-old boy with median cleft palate, surgically reconstructed cleft lip, hypotelorism with a flat nose, cryptorchidism, clubfoot, and microcephaly. During the laboratory investigation, his blood sodium level was 154 mmol/L and urine specific gravity was 1.007. Serum osmolarity was 317 mOsm/kg and urine osmolarity was 268 mOsm/kg. Given these findings and the clinical response to vasopressin, diagnosis of central diabetes insipidus was made. Magnetic resonance imaging revealed semilobar holoprosencephaly. The patient responded very well to vasopressin treatment with restoration of serum electrolytes, which remained within normal limits on follow-up. In case of midline facial defects accompanied by hypotelorism with or without developmental delay, the brain should be imaged to confirm its morphology and investigations should be directed by a high index of suspicion of associated endocrinologic dysfunctions.

  12. Pharmacokinetics and Safety of Caspofungin in Neonates and Infants Less than 3 Months of Age▿

    PubMed Central

    Sáez-Llorens, Xavier; Macias, Mercedes; Maiya, Padmanabha; Pineros, Juan; Jafri, Hasan S.; Chatterjee, Archana; Ruiz, Gloria; Raghavan, Janaki; Bradshaw, Susan K.; Kartsonis, Nicholas A.; Sun, Peng; Strohmaier, Kim M.; Fallon, Marissa; Bi, Sheng; Stone, Julie A.; Chow, Joseph W.

    2009-01-01

    Candida infections represent a major threat in neonatal intensive care units. This is the first prospective study to obtain caspofungin plasma levels and safety data for neonates and very young infants. Patients of <3 months of age receiving intravenous amphotericin B for documented or highly suspected candidiasis were enrolled in a single-dose (n = 6) or subsequent multiple-dose (n = 12) panel; all received caspofungin at 25 mg/m2 once daily as a 1-hour infusion. Caspofungin plasma levels were measured by high-performance liquid chromatography and compared to historical data from adults. Patient chronological ages ranged from 1 to 11 weeks, and weights ranged from 0.68 to 3.8 kg. Gestational ages ranged from 24 to 41 weeks. Geometric mean (GM) peak (C1 h) and trough (C24 h) caspofungin levels were 8.2 and 1.8 μg/ml, respectively, on day 1, and 11.1 and 2.4 μg/ml, respectively, on day 4. GM ratios for C1 h and C24 h for neonates/infants relative to adults receiving caspofungin at 50 mg/day were 1.07 and 1.36, respectively, on day 1, and 1.18 and 1.21, respectively, on day 4. Clinical and laboratory adverse events occurred in 17 (94%) and 8 (44%) patients, respectively. Five patients (28%) had serious adverse events, none of which were considered drug related. Caspofungin at 25 mg/m2 once daily was well tolerated in this group of neonates/infants of <3 months of age and appears to provide relatively similar plasma exposure to that obtained in adults receiving 50 mg/day. However, the small number of patients studied precludes any definitive recommendations about caspofungin dosing for this group comprising a broad range of ages and weights. PMID:19075070

  13. Wave-wave interactions in the stratosphere - Observations during quiet and active wintertime periods

    NASA Technical Reports Server (NTRS)

    Smith, A. K.; Gille, J. C.; Lyjak, L. V.

    1984-01-01

    Smith (1983) has demonstrated that wave-wave interactions among planetary waves 1, 2, and 3 were important during the month of January 1979, a period characterized by extremely large wave 1 amplitudes in the stratosphere. In the present investigation, the same analysis is applied to the period November 1978 through March 1979 with the aim to determine the conditions under which wave-wave interactions were important. Attention is given to enstrophy budget calculations, the wave 1/wave 2 vacillation, a quantitative measure of wave-wave interactions, and examples of wave-wave interactions during several periods. It is found that the vacillation between waves 1 and 2 has no clear relationship to the tropopause forcing as represented by the 300 mb amplitude.

  14. Coronal quasi-periodic fast-propagating magnetosonic waves observed by SDO/AIA

    NASA Astrophysics Data System (ADS)

    Shen, Yuandeng

    Coronal quasi-periodic fast-propagating (QFP) magnetosonic waves are scare in previous studies due to the relative low temporal and spatial resolution of past telescopes. Recently, they are detected by the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory (SDO). Here, two cases of QFP waves are presented. The analysis results indicate that QFP waves are tightly associated with the associated flares. It is indicate that QFP waves and the associated flares are possibly driven by the same physic process such as quasi-periodic magnetic reconnection process in producing flares.

  15. Intra-Arterial Chemotherapy as Primary Therapy for Retinoblastoma in Infants Less than 3 Months of Age: A Series of 10 Case-Studies

    PubMed Central

    Xia, Jiejun; Liu, Zhenyin; Jiang, Hua; Shen, Gang; Li, Haibo; Jiang, Yizhou; Zhang, Jing

    2016-01-01

    Purpose Retinoblastoma is the most common primary malignant intra-ocular tumor in children. Although intra-arterial chemotherapy (IAC) by selectively infusing chemotherapy through the ophthalmic artery has become an essential technique in the treatment of advanced intra-ocular retinoblastoma in children, the outcome of IAC as primary therapy for infants less than 3 months of age remains unknown. In this retrospective study, we reviewed the outcome of IAC as primary therapy for retinoblastoma in infants less than 3 months of age. Methods We retrospectively reviewed ten retinoblastoma patients attending our center from January 2009 to September 2015 and beginning primary IAC before the age of 3 months. The patient characteristics, overall outcomes and therapy-related complications were assessed. Results The mean patient age at the first IAC treatment was 10.4 weeks (range 4.9–12.9 weeks). These eyes were classified according to the International Classification of Retinoblastoma (ICRB) as group A (n = 0), B (n = 2), C (n = 0), D (n = 9), or E (n = 2). A total of 28 catheterizations were performed, and the procedure was stopped in one patient because of internal carotid artery spasm. Each eye received a mean of 2.6 cycles of IAC (range 2–4 cycles). After IAC with a mean follow-up of 28.3 months (range 9–65 months), tumor regression was observed in 12 of 13 eyes. One eye was enucleated due to tumor progression. All patients are alive and no patient has developed metastatic disease or other malignancies. Conclusions Our experience suggests IAC as primary therapy is a feasible and promising treatment for retinoblastoma in infants less than 3 months of age. PMID:27504917

  16. The Impact of Patient Education on Anthropometric, Lipidemic, and Glycemic Parameters Among Patients With Poorly Controlled Type II Diabetes Mellitus: A 3-Month Prospective Single-Center Turkish Study.

    PubMed

    Cander, Soner; Gul, Ozen Oz; Gul, Cuma B; Keles, Saadet B; Yavas, Sibel; Ersoy, Canan

    2014-12-01

    This study evaluated the impact of patient education on adherence to a diabetes care plan (e.g., anthropometric, lipidemic, and glycemic parameters) among adults with type II diabetes mellitus without adequate glycemic control. A total of 61 ambulatory adults with type II diabetes mellitus (mean age: 53.6 ± 8.2 years, 70.5% female) were evaluated for anthropometrics, duration of diabetes mellitus, type of anti-diabetic treatment, blood biochemistry, and glycemic parameters in this 3-month prospective observational single-center study. During the course of the study, participants demonstrated a significant decrease in body weight and fat percentage and HbA1c (p < .001 for each). None of the factors evaluated was a significant determinant for glycemic parameters. These findings revealed that adults with type II diabetes mellitus who received education on adherence to routine self-monitoring of blood glucose, standard diabetic diet, and an exercise program delivered by certified diabetes educators had better glycemic control and significant decrease in body weight and fat percentage over a 3-month monitoring period.

  17. How the Initial Thinking Period Affects Student Argumentation during Peer Instruction: Students' Experiences versus Observations

    ERIC Educational Resources Information Center

    Nielsen, Kjetil L.; Hansen, Gabrielle; Stav, John B.

    2016-01-01

    The authors have compared students discussing multiple-choice quizzes during peer instruction with and without the initial thinking period before discussion. Video clips of students engaged in peer discussion in groups of three of varying group combinations, a total of 140 different students in all, were compared to students' own experiences…

  18. Meridional Circulation Cells Observed In The Upper Troposphere Over Suriname During The Monsoon Period

    NASA Astrophysics Data System (ADS)

    Fortuin, P.; Kelder, H.

    Since September 1999, weekly balloon sondes are released at tropical Paramaribo sta- tion (5.8N 55.2W), located at the northern coast of South America. The station lies approximately in the middle of the annual migration range of the ITCZ, and therefore experiences either a northeast or a southeast trade wind regime (ITCZ respectively to the south, north). The wet season corresponds with the period of northeasterly trade winds (December-July) and is normally interrupted by a short dry period (February- March) when the ITCZ lies farthest to the south. During this monsoon period a sys- tematic return flow to higher latitudes can be detected, centered around 12 km (200 hPa), which seems to constitute the upper branch of the Hadley cell. However, this upper branch of the Hadley cell seems to be flanked above and below by southward flow. On closer inspection, these meridional sub-cells persist in a domain of negative potential vorticity, brought about by the horizontal gradient in zonal wind near the Equator as the northern subtropical jet reaches its southern-most point. As predicted by Stevens (1982), this inertially unstable domain responds with vertically sctacked meridional flow cells, in order to restore a minimum horizontal shear in zonal wind near the Equator. These meridional cells continuously exhibit alternating periods of growth and decay, on a time-scale consistent with inertial instability. Their meridional extent is from the Equator to approcimately 10-12 degrees North, such that Paramaribo (at 5.8N) witnesses approximately the maximal merinional wind velocity near the cen- ter of these cells. Due to their persistent recurring nature in the monsoon period, they leave a signature on the water vapor distribution in the upper troposphere, which shows a dry layer sandwithced between wetter layers - with a spatial distribution similar to the sub-cellular flow.

  19. IUE observations of periodic comets Tempel-2, Kopff, and Tempel-1

    NASA Technical Reports Server (NTRS)

    Feldman, Paul D.; Festou, Michel C.

    1992-01-01

    We summarize the results of observations made between 10 Jun. - 18 Dec. 1988 with the International Ultraviolet Explorer (IUS) of comet P/Tempel-2 during its 1988 appearance. The derived water production rate and relative gas/dust ratio are compared with those of P/Halley, observed with IUE in 1985-86, and other potential Comet Rendezvous/Asteroid Flyby (CRAF) target comets, P/Kopff and P/Tempel-1, both observed with IUE in 1983.

  20. Estimating the period and Q of the Chandler Wobble from observations and models of its excitation (Abstract)

    NASA Astrophysics Data System (ADS)

    Gross, R.; Nastula, J.

    2015-08-01

    Any irregularly shaped solid body rotating about some axis that is not aligned with its figure axis will freely wobble as it rotates. For the Earth, this free wobble is known as the Chandler wobble in honor of S.C. Chandler, Jr. who first observed it in 1891. Unlike the forced wobbles of the Earth, such as the annual wobble, whose periods are the same as the periods of the forcing mechanisms, the period of the free Chandler wobble is a function of the internal structure and rheology of the Earth, and its decay time constant, or quality factor Q, is a function of the dissipation mechanism(s), like mantle anelasticity, that are acting to dampen it. Improved estimates of the period and Q of the Chandler wobble can therefore be used to improve our understanding of these properties of the Earth. Here, estimates of the period and Q of the Chandler wobble are obtained by finding those values that minimize the power within the Chandler band of the difference between observed and modeled polar motion excitation spanning 1962- 2010. Atmosphere, ocean, and hydrology models are used to model the excitation caused by both mass and motion variations within these global geophysical fluids. Direct observations of the excitation caused by mass variations as determined from GRACE time varying gravitational field measurements are also used. The resulting estimates of the period and Q of the Chandler wobble will be presented along with a discussion of the robustness of the estimates.

  1. Variation of Acoustic Cutoff Period with Height in the Solar Atmosphere: Theory versus Observations

    NASA Astrophysics Data System (ADS)

    Murawski, K.; Musielak, Z. E.; Konkol, P.; Wiśniewska, A.

    2016-08-01

    Recently Wiśniewska et al. demonstrated observationally how the acoustic cutoff frequency varies with height in the solar atmosphere including the upper photosphere and the lower and middle chromosphere, and showed that the observational results cannot be accounted for by the existing theoretical formulas for the acoustic cutoff. In order to reproduce the observed variation of the cutoff with atmospheric height, numerical simulations of impulsively generated acoustic waves in the solar atmosphere are performed, and the spectral analysis of temporal wave profiles is used to compute numerically changes of the acoustic cutoff with height. Comparison of the numerical results with the observational data shows good agreement, which clearly indicates that the obtained results may be used to determine the structure of the background solar atmosphere.

  2. Spatial log-periodic oscillations of first-passage observables in fractals.

    PubMed

    Akkermans, Eric; Benichou, Olivier; Dunne, Gerald V; Teplyaev, Alexander; Voituriez, Raphael

    2012-12-01

    For transport processes in geometrically restricted domains, the mean first-passage time (MFPT) admits a general scaling dependence on space parameters for diffusion, anomalous diffusion, and diffusion in disordered or fractal media. For transport in self-similar fractal structures, we obtain an expression for the source-target distance dependence of the MFPT that exhibits both the leading power-law behavior, depending on the Hausdorff and spectral dimension of the fractal, as well as small log-periodic oscillations that are a clear and definitive signal of the underlying fractal structure. We also present refined numerical results for the Sierpinski gasket that confirm this oscillatory behavior.

  3. [The academic trend of Oriental medicine during the Japanese colonial period as observed through the publication of medical books].

    PubMed

    Kim, Nam-Il

    2006-06-01

    This thesis examines the academical trend of Oriental Medicine in the Japanese colonial period observed through medical books published during the Japanese colonial period. This is a period in which Western Medicine was introduced, and due to the lean-to-one-side policy by the Japanese, Western Medicine became the mainstream medical science while Oriental Medicine was pushed to the outskirts. Even after all this, the academic activity was flourishing during this period compared to any other periods. This article is divided into various chapters each with its own theme in order to understand the academic trend of Oriental Medicine during the Japanese colonial period. Focusing on the publication of medical books, this article is divided and observed according to various themes such as the study of Dong-Eui-Bo-Gam (see text), the study of Bang-Yak-Hap-Pyeun (see text), the study of Sang-Han-Ron (see text), the study of Sa-sang (see text) constitutional medicine, the study of Eui-Hak-Ip-Mun (see text), the study about Bu-Yang-Ron (see text), On-Bo-Ron (see text), and pediatrics, compromise between Western and Oriental Medicine, the study of experience medicine, the study of acupuncture and moxibustion, and etc.

  4. Contingency Learning and Reactivity in Preterm and Full-Term Infants at 3 Months

    PubMed Central

    Haley, David W.; Grunau, Ruth E.; Oberlander, Tim F.; Weinberg, Joanne

    2010-01-01

    Learning difficulties in preterm infants are thought to reflect impairment in arousal regulation. We examined relationships among gestational age, learning speed, and behavioral and physiological reactivity in 55 preterm and 49 full-term infants during baseline, contingency, and nonreinforcement phases of a conjugate mobile paradigm at 3 months corrected age. For all infants, negative affect, looking duration, and heart rate levels increased during contingency and nonreinforcement phases, whereas respiratory sinus arrhythmia (RSA, an index of parasympathetic activity) decreased and cortisol did not change. Learners showed greater RSA suppression and less negative affect than nonlearners. This pattern was particularly evident in the preterm group. Overall, preterm infants showed less learning, spent less time looking at the mobile, and had lower cortisol levels than full-term infants. Preterm infants also showed greater heart rate responses to contingency and dampened heart rate responses to nonreinforcement compared to full-term infants. Findings underscore differences in basal and reactivity measures in preterm compared to full-term infants and suggest that the capacity to regulate parasympathetic activity during a challenge enhances learning in preterm infants. PMID:20717491

  5. Ecthyma gangrenosum in a 3-month-old, previously healthy infant

    PubMed Central

    Zhang, Xiao-ting; Jin, Wan-wan; Ma, Xin-hua; Yu, Hai-feng; Tang, Xu-hua

    2017-01-01

    Abstract Rationale: Ecthyma gangrenosum (EG) is an aggressive cutaneous disease caused by local or systemic infection with Pseudomonas aeruginosa. EG is characterized by cutaneous manifestations ranging from nodule and papule, to necrotic ulceration with surrounding erythema, especially with black eschar or central crust. EG presents with characteristic skin lesions which is important to establish diagnosis of sepsis caused by P aeruginosa, a serious condition that can be treated efficiently if diagnosed early. Patient concerns: A 3-month-old female infant was presented with characteristic skin lesions of EG and developed sepsis 3 days later. Diagnoses: Ecthyma gangrenosum and sepsis caused by Pseudomonas aeruginosa. Interventions: Meropenem was used in combination with ceftazidime at first and excision of necrotic skin lesions was performed later. Outcomes: Cure. Lessons: Early recognition of EG plays an important role in providing appropriate empiric antibiotic treatment at early stage of sepsis, and improves the prognosis. Surgical excision may be helpful if no improvement was achieved via antibiotic treatment. PMID:28272221

  6. Observation of a periodic pattern in the persistent-current fields of the superconducting HERA magnets

    SciTech Connect

    Brueck, H.; Gall, D.; Krzywinski, J.; Meinke, R.; Preissner, H. , Hamburg ); Halemeyer, M.; Schmueser, P.; Stolzenburg, C. . 2. Inst. fuer Experimentalphysik); Stiening, R. ); ter Avest, D.; van de Klundert, L.J.M. (Technische Hogeschool Twente, Enschede (Netherlands

    1991-05-01

    The time dependence of persistent current multipoles in superconducting magnets is still unexplained. The decay is too large to be accounted for by flux creep and it does not show the expected dependence on temperature. Furthermore the decay is influenced by a preceding field sweep in the magnet, it becomes more pronounced if the magnet was previously excited to its maximum field. For a detailed study of the decay mechanism a special sensor has been developed which allows to record small sexupole components in superconducting dipole magnets. During an experimental study of the time dependence of a HERA dipole it was found that the sextupole field exhibits a sinusoidal structure along the axis of the magnet. A similar periodic structure was found for the main dipole field with the help of a nuclear magnetic resonance probe. The wavelength of the periodic pattern is compatible with the transposition pitch of the Rutherford-type cable in the magnet coils. The structure was found to exist in all HERA dipoles measured afterwards and also in a superconducting coil without iron yoke. With a specially developed 2 cm long pickup coil it was found that all accessible multipole components in dipole and quadrupole magnets are modulated along their axis. 3 refs., 6 figs.

  7. Daytime Raman lidar measurements of water vapor during the ARM 1997 water vapor intensive observation period

    SciTech Connect

    Turner, D.D.; Goldsmith, J.E.M.

    1998-04-01

    Because of the importance of water vapor, the ARM program initiated a series of three intensive operating periods (IOPs) at its CART (Cloud And Radiation Testbed) site. The goal of these IOPs is to improve and validate the state-of-the-art capabilities in measuring water vapor. To date, two of the planned three IOPs have occurred: the first was in September of 1996, with an emphasis on the lowest kilometer, while the second was conducted from September--October 1997 with a focus on both the upper troposphere and lowest kilometer. These IOPs provided an excellent opportunity to compare measurements from other systems with those made by the CART Raman lidar. This paper addresses primarily the daytime water vapor measurements made by the lidar system during the second of these IOPs.

  8. [Cost of illness in Parkinson disease. A retrospective 3-month analysis of direct costs].

    PubMed

    Dodel, R C; Singer, M; Köhne-Volland, R; Selzer, R; Scholz, W; Rathay, B; Oertel, W H

    1997-12-01

    Parkinson's disease (PD) causes significant expense for the national health care system due to its chronic progressive course, the duration of the disease, the high prevalence and the devastating prognosis. In Germany more than DM 320 million are spent for drugs to alleviate parkinsonian symptoms. The aim of this study was to calculate the economic burden of PD by assessing direct medical costs. Forty patients suffering from idiopathic PD were interviewed at an office of neurological specialists and at an outpatient movement disorder clinic about their use of health care resources 3 months prior to the study. The total annual costs reported were DM 14,500, consisting of DM 6500 for drug therapy and DM 8000 for other medical services, including hospital inpatient care (DM 5600), outpatient care (DM 700), medical sundries (DM 1100) and physiotherapy (DM 600). The costs were positively correlated to the extent of the disease (Hoehn and Yahr stage; HY) and the occurrence of motor fluctuations/dyskinesias. We found that both drug-therapy expenses and total medical costs doubled from HYI to HYIV. The rarely employed s.c. therapy with apomorphine additionally increased the costs of drug therapy in HYV. The occurrence of fluctuations/ dyskinesias also increased medical expenses by approximately a factor of two. Indirect burden due to increased days off of work, unemployment and earlier retirement are also significant in Parkinson's disease. This study includes that a treatment which could prevent or retard disease progression as well as a treatment that delays or reduces motor complications would not only ameliorate the situation of patients suffering from PD, but would also lead to significant reductions in cost for the national health care system.

  9. The BREASTrial Stage II: ADM Breast Reconstruction Outcomes from Definitive Reconstruction to 3 Months Postoperative

    PubMed Central

    Mendenhall, Shaun D.; Anderson, Layla A.; Ying, Jian; Boucher, Kenneth M.; Neumayer, Leigh A.

    2017-01-01

    Background: The Breast Reconstruction Evaluation of Acellular Dermal Matrix as a Sling Trial is a prospective randomized trial comparing outcomes of tissue expander breast reconstruction using either AlloDerm or DermaMatrix. The trial was divided into 3 outcome stages; this study reports stage II outcomes, which are those from the time of definitive reconstruction to 3 months postoperative. Methods: A randomized trial was conducted to compare complication rates between AlloDerm and DermaMatrix groups. The impact of matrix type, age, obesity, radiation therapy, chemotherapy, and reconstruction type on complications was analyzed with regression models. Results: Of the 128 patients (199 breasts) who were randomly assigned into the trial, 111 patients (173 breasts) were available for analysis in stage II. There was no difference in overall rates of complications (15.4% vs 18.3%, P = 0.8) or implant loss (2.2% vs 3.7%, P = 0.5) between the AlloDerm and DermaMatrix groups, respectively. Obesity was the only significant predictor of complications on regression analysis (odds ratio, 4.31, P = 0.007). Matrix type, age, radiation therapy, chemotherapy, or reconstruction type had no impact on the incidence/severity of complications. Conclusions: Acellular dermal matrix (ADM) will likely continue to have a role in breast reconstructive surgery; however, caution should be taken when using ADM because of relatively high complication rates, especially in obese patients. The particular ADM product should be selected based on individual surgeon preference, experience, and success rates. These data and forthcoming long-term outcomes from the Breast Reconstruction Evaluation of Acellular Dermal Matrix as a Sling Trial will enable surgeons to carefully weigh the risks and benefits of ADM use in breast reconstruction. PMID:28203509

  10. Prevalence and risk factors of posttraumatic stress disorder among teachers 3 months after the Lushan earthquake

    PubMed Central

    Zhang, Jun; Zhang, Ye; Du, Changhui; Zhu, Shenyue; Huang, Yalin; Tian, Yulian; Chen, Decao; Li, Haimin; Gong, Yao; Zhang, Mengmeng; Gu, Bo

    2016-01-01

    Abstract Teachers and students often suffer from the same disaster. The prevalence of PTSD in students has been given great attention. However, in acting as mentors to students and their families, teachers are more likely to have vicarious and indirect exposure via hearing stories of their aftermath and witnessing the consequences of traumatic events. There are limited data pertaining to the prevalence of PTSD and its risk factors among teachers. A total of 316 teachers from 21 primary and secondary schools in Baoxing County were administered a project-developed questionnaire which included the items regarding demographic characteristics, earthquake-related experiences, somatic discomforts, emotional reactions, support status, and everyday functioning 2 weeks after the Lushan earthquake, and they finished a 1-to-1 telephone interview for addressing the PTSD criteria of the Mini International Neuropsychiatric Interview (MINI) 3 months after the earthquake. The prevalence of PTSD was 24.4% among teachers. Somatic discomforts (odds ratio [OR] 1.89, 95% confidence interval [CI] 1.06–3.37) were positive risk factors of PTSD. Perceived social support (OR 0.30, 95% CI 0.14–0.62) and being able to calm down (OR 0.25, 95% CI 0.09–0.75) in teaching were negative risk factors. PTSD is commonly seen among teachers after an earthquake, and risk factors of PTSD were identified. These findings may help those providing psychological health programs to find the teachers who are at high risk of PTSD in schools after an earthquake in China. PMID:27442675

  11. Cassini Observations of Saturn's Nightside UV Auroral Oval: In Situ Evidence of its Periodic Motion

    NASA Astrophysics Data System (ADS)

    Bunce, E. J.; Grodent, D. C.; Provan, G.; Jinks, S.; Cowley, S. W.; Andrews, D. J.; Arridge, C. S.; Badman, S. V.; Dougherty, M. K.; Kurth, W. S.; Mitchell, D. G.

    2012-12-01

    In recent years we have benefitted greatly from the first in-orbit multi-wavelength images of Saturn's polar atmosphere from the Cassini spacecraft. Specifically, images obtained from the UltraViolet Imaging Spectrograph (UVIS) on board the Cassini spacecraft provide an excellent view of the planet's auroral emissions, which in turn give an account of the large-scale magnetosphere-ionosphere coupling and dynamics within the system. However, obtaining a simultaneous view of the auroral regions with measurements of the magnetic field and plasma populations at high-latitudes is more difficult to routinely achieve. Here we present an unusual example, during Revolution 99 in 2009, where UVIS images the entire northern UV auroral oval while Cassini traverses the magnetic flux tubes connecting to the auroral oval on the nightside sampling the related magnetic field and particle signatures present. We will discuss the relationship of the field-aligned currents (derived from the magnetic field), radio waves, and associated plasma electron and ion signatures to the properties of the auroral oval. The motion of the auroral oval evident in the UVIS images will be discussed in the context of the "planetary period oscillations" and previous field-aligned current studies.Credit: NASA/JPL/University of Colorado/ESA/University of Liege/University of Leicester

  12. Higher Retail Prices of Sugar-Sweetened Beverages 3 Months After Implementation of an Excise Tax in Berkeley, California

    PubMed Central

    Rojas, Nadia; Grummon, Anna H.; Madsen, Kristine A.

    2015-01-01

    Objectives. We assessed the short-term ability to increase retail prices of the first US 1-cent-per-ounce excise tax on the distribution of sugar-sweetened beverages (SSBs), which was implemented in March 2015 by Berkeley, California. Methods. In 2014 and 2015, we examined pre- to posttax price changes of SSBs and non-SSBs in a variety of retailers in Berkeley and in the comparison cities Oakland and San Francisco, California. We examined price changes by beverage, brand, size, and retailer type. Results. For smaller beverages (≤ 33.8 oz), price increases (cents/oz) in Berkeley relative to those in comparison cities were 0.69 (95% confidence interval [CI] = 0.36, 1.03) for soda, 0.47 (95% CI = 0.08, 0.87) for fruit-flavored beverages, and 0.47 (95% CI = 0.25, 0.69) for SSBs overall. For 2-liter bottles and multipacks of soda, relative price increases were 0.46 (95% CI = 0.03, 0.89) and 0.49 (95% CI = 0.21, 0.77). We observed no relative price increases for nontaxed beverages overall. Conclusions. Approximately 3 months after the tax was implemented, SSB retail prices increased more in Berkeley than in nearby cities, marking a step in the causal pathway between the tax and reduced SSB consumption. PMID:26444622

  13. Tidally distorted exoplanets: Density corrections for short-period hot-Jupiters based solely on observable parameters

    SciTech Connect

    Burton, J. R.; Watson, C. A.; Fitzsimmons, A.; Moulds, V.; Pollacco, D.; Wheatley, P. J.; Littlefair, S. P.

    2014-07-10

    The close proximity of short-period hot-Jupiters to their parent star means they are subject to extreme tidal forces. This has a profound effect on their structure and, as a result, density measurements that assume that the planet is spherical can be incorrect. We have simulated the tidally distorted surface for 34 known short-period hot-Jupiters, assuming surfaces of constant gravitational equipotential for the planet, and the resulting densities have been calculated based only on observed parameters of the exoplanet systems. Comparing these results to the density values, assuming the planets are spherical, shows that there is an appreciable change in the measured density for planets with very short periods (typically less than two days). For one of the shortest-period systems, WASP-19b, we determine a decrease in bulk density of 12% from the spherical case and, for the majority of systems in this study, this value is in the range of 1%-5%. On the other hand, we also find cases where the distortion is negligible (relative to the measurement errors on the planetary parameters) even in the cases of some very short period systems, depending on the mass ratio and planetary radius. For high-density gas planets requiring apparently anomalously large core masses, density corrections due to tidal deformation could become important for the shortest-period systems.

  14. OBSERVING EVOLUTION IN THE SUPERGRANULAR NETWORK LENGTH SCALE DURING PERIODS OF LOW SOLAR ACTIVITY

    SciTech Connect

    McIntosh, Scott W.; Rast, Mark P.; Leamon, Robert J.; Hock, Rachel A.; Ulrich, Roger K.

    2011-03-20

    We present the initial results of an observational study into the variation of the dominant length scale of quiet solar emission: supergranulation. The distribution of magnetic elements in the lanes that from the network affects, and reflects, the radiative energy in the plasma of the upper solar chromosphere and transition region at the magnetic network boundaries forming as a result of the relentless interaction of magnetic fields and convective motions of the Suns' interior. We demonstrate that a net difference of {approx}0.5 Mm in the supergranular emission length scale occurs when comparing observation cycle 22/23 and cycle 23/24 minima. This variation in scale is reproduced in the data sets of multiple space- and ground-based instruments and using different diagnostic measures. By means of extension, we consider the variation of the supergranular length scale over multiple solar minima by analyzing a subset of the Mount Wilson Solar Observatory Ca II K image record. The observations and analysis presented provide a tantalizing look at solar activity in the absence of large-scale flux emergence, offering insight into times of 'extreme' solar minimum and general behavior such as the phasing and cross-dependence of different components of the spectral irradiance. Given that the modulation of the supergranular scale imprints itself in variations of the Suns' spectral irradiance, as well as in the mass and energy transport into the entire outer atmosphere, this preliminary investigation is an important step in understanding the impact of the quiet Sun on the heliospheric system.

  15. Observing Evolution in the Supergranular Network Length Scale During Periods of Low Solar Activity

    NASA Astrophysics Data System (ADS)

    McIntosh, Scott W.; Leamon, Robert J.; Hock, Rachel A.; Rast, Mark P.; Ulrich, Roger K.

    2011-03-01

    We present the initial results of an observational study into the variation of the dominant length scale of quiet solar emission: supergranulation. The distribution of magnetic elements in the lanes that from the network affects, and reflects, the radiative energy in the plasma of the upper solar chromosphere and transition region at the magnetic network boundaries forming as a result of the relentless interaction of magnetic fields and convective motions of the Suns' interior. We demonstrate that a net difference of ~0.5 Mm in the supergranular emission length scale occurs when comparing observation cycle 22/23 and cycle 23/24 minima. This variation in scale is reproduced in the data sets of multiple space- and ground-based instruments and using different diagnostic measures. By means of extension, we consider the variation of the supergranular length scale over multiple solar minima by analyzing a subset of the Mount Wilson Solar Observatory Ca II K image record. The observations and analysis presented provide a tantalizing look at solar activity in the absence of large-scale flux emergence, offering insight into times of "extreme" solar minimum and general behavior such as the phasing and cross-dependence of different components of the spectral irradiance. Given that the modulation of the supergranular scale imprints itself in variations of the Suns' spectral irradiance, as well as in the mass and energy transport into the entire outer atmosphere, this preliminary investigation is an important step in understanding the impact of the quiet Sun on the heliospheric system.

  16. Suzaku And Multi-Wavelength Observations of OJ 287 During the Periodic Optical Outburst in 2007

    SciTech Connect

    Seta, Hiromi; Isobe, N.; Tashiro, Makoto S.; Yaji, Yuichi; Arai, Akira; Fukuhara, Masayuki; Kohno, Kotaro; Nakanishi, Koichiro; Sasada, Mahito; Shimajiri, Yoshito; Tosaki, Tomoka; Uemura, Makoto; Anderhub, Hans; Antonelli, L.A.; Antoranz, Pedro; Backes, Michael; Baixeras, Carmen; Balestra, Silvia; Barrio, Juan Abel; Bastieri, Denis; Becerra Gonzalez, Josefa; /IAC, La Laguna /Dortmund U. /Lodz U. /Lodz U. /DESY /Zurich, ETH /Munich, Max Planck Inst. /Padua U. /INFN, Padua /Siena U. /INFN, Siena /Barcelona, IEEC /Munich, Max Planck Inst. /Barcelona, IEEC /Madrid U. /Zurich, ETH /Wurzburg U. /Zurich, ETH /Madrid U. /Munich, Max Planck Inst. /Zurich, ETH /Madrid U. /Barcelona, IFAE /IAC, La Laguna /Laguna U., Tenerife /INFN, Rome /Dortmund U. /Udine U. /INFN, Udine /INFN, Padua /Udine U. /INFN, Udine /Barcelona, IEEC /Madrid U. /Udine U. /INFN, Udine /Udine U. /INFN, Udine /Udine U. /INFN, Udine /IAC, La Laguna /Madrid, CIEMAT /Sierra Nevada Observ. /Zurich, ETH /Padua U. /INFN, Padua /Wurzburg U. /Barcelona, IFAE /UC, Davis /Barcelona, IFAE /Barcelona, IFAE /Madrid U. /Barcelona, Autonoma U. /Munich, Max Planck Inst. /IAC, La Laguna /Laguna U., Tenerife /Barcelona, IFAE /IAC, La Laguna /Munich, Max Planck Inst. /Barcelona, Autonoma U. /Munich, Max Planck Inst. /SLAC /IAC, La Laguna /Laguna U., Tenerife /Zurich, ETH /Wurzburg U. /Munich, Max Planck Inst. /Munich, Max Planck Inst. /Munich, Max Planck Inst. /Zurich, ETH /INFN, Rome /UC, Davis /Siena U. /INFN, Siena /Turku U. /Padua U. /INFN, Padua /Udine U. /INFN, Udine /Padua U. /INFN, Padua /Zurich, ETH /Munich, Max Planck Inst. /DESY /Sofiya, Inst. Nucl. Res. /Udine U. /INFN, Udine /Wurzburg U. /INFN, Rome /Padua U. /INFN, Padua /Barcelona, IFAE /Barcelona, IFAE /Siena U. /INFN, Siena /Wurzburg U. /Madrid U. /Munich, Max Planck Inst. /Munich, Max Planck Inst. /Barcelona, IEEC /Sierra Nevada Observ. /Barcelona, IFAE /Madrid U. /Turku U. /Munich, Max Planck Inst. /Munich, Max Planck Inst. /UC, Santa Cruz /Madrid U. /Siena U. /INFN, Siena /Barcelona, IEEC /Turku U. /Padua U. /INFN, Padua /Zurich, ETH /Siena U. /INFN, Siena /Sierra Nevada Observ. /Udine U. /INFN, Udine /INFN, Trieste /Padua U. /INFN, Padua /Sierra Nevada Observ. /Padua U. /INFN, Padua /Barcelona, IFAE /Barcelona, IFAE /Dortmund U. /Barcelona, IEEC /ICREA, Barcelona /Barcelona, IFAE /Zurich, ETH /Barcelona, Autonoma U. /Wurzburg U. /Padua U. /INFN, Padua /Munich, Max Planck Inst. /INFN, Rome /Sierra Nevada Observ. /DESY /Padua U. /INFN, Padua /Udine U. /INFN, Udine /Munich, Max Planck Inst. /Munich, Max Planck Inst. /Pisa U. /INFN, Pisa /Barcelona, IFAE /Barcelona, IEEC /Turku U. /Munich, Max Planck Inst. /Lodz U. /Lodz U. /Wurzburg U. /Siena U. /INFN, Siena /Zurich, ETH /Turku U. /INFN, Rome /Sofiya, Inst. Nucl. Res. /Barcelona, IFAE /Munich, Max Planck Inst. /DESY /ICREA, Barcelona /Barcelona, IEEC /Siena U. /INFN, Siena /Sofiya, Inst. Nucl. Res. /Munich, Max Planck Inst. /Munich, Max Planck Inst. /Barcelona, IEEC /Sierra Nevada Observ. /Barcelona, IFAE /Barcelona, Autonoma U.

    2011-12-01

    Suzaku observations of the blazar OJ 287 were performed in 2007 April 10-13 and November 7-9. They correspond to a quiescent and a flaring state, respectively. The X-ray spectra of the source can be well described with single power-law models in both exposures. The derived X-ray photon index and the flux density at 1 keV were found to be {Lambda} = 1.65 {+-} 0.02 and S{sub 1keV} = 215 {+-} 5 nJy, in the quiescent state. In the flaring state, the source exhibited a harder X-ray spectrum ({Lambda} = 1.50 {+-} 0.01) with a nearly doubled X-ray flux density S{sub 1keV} = 404{sub -5}{sup +6} nJy. Moreover, significant hard X-ray signals were detected up to {approx} 27 keV. In cooperation with the Suzaku, simultaneous radio, optical, and very-high-energy {gamma}-ray observations of OJ 287 were performed with the Nobeyama Millimeter Array, the KANATA telescope, and the MAGIC telescope, respectively. The radio and optical fluxes in the flaring state (3.04 {+-} 0.46 Jy and 8.93 {+-} 0.05 mJy at 86.75 Hz and in the V-band, respectively) were found to be higher by a factor of 2-3 than those in the quiescent state (1.73 {+-} 0.26 Jy and 3.03 {+-} 0.01 mJy at 86.75 Hz and in the V-band, respectively). No notable {gamma}-ray events were detected in either observation. The spectral energy distribution of OJ 287 indicated that the X-ray spectrum was dominated by inverse Compton radiation in both observations, while synchrotron radiation exhibited a spectral cutoff around the optical frequency. Furthermore, no significant difference in the synchrotron cutoff frequency was found between the quiescent and flaring states. According to a simple synchrotron self-Compton model, the change of the spectral energy distribution is due to an increase in the energy density of electrons with small changes of both the magnetic field strength and the maximum Lorentz factor of electrons.

  17. Observations and modelling of winds and waves during the surface wave dynamics experiment. Report 2. Intensive observation period IOP-3, 25 February-9 March 1991. Technical report

    SciTech Connect

    Caruso, M.J.; Graber, H.C.; Jensen, R.E.; Donelan, M.A.

    1994-03-01

    This report describes the compilation of observed and modelled wind, wave and current parameters during the third intensive observation period (IOP-3) from February 25 to March 9, 1991, of the Surface Wave Dynamics Experiment. The measurements include wind speed and direction, wave heights and periods, air and sea temperatures, and atmospheric pressures from four directional wave buoys, two meteorological buoys, and several routinely operated buoys from the National Data Buoy Center (NDBC). Examples of directional wave spectra obtained from two airborne radars and from a Swath ship are presented along with surface currents from airborne expendable current profilers (AXCP) and acoustic doppler current profilers (ADCP). In addition, a summary of directional wave spectra is presented for this period. The model data include examples of wind fields from six numerical weather prediction models and the corresponding wave height maps as derived from the 3G-WAM ocean wave model. Estimated surface current velocities and directions from the Fleet Numerical Oceanographic Center (FNOC) model and selected satellite images of sea surface temperature fields are also presented for this time period.

  18. Weekly periodicities of aerosol properties observed at an urban location in India

    SciTech Connect

    Satheesh, S K; Vinoj, V; Moorthy, K Krishna

    2011-07-01

    Multi-year (~7 years) observations of aerosol optical and microphysical properties were conducted at a tropical urban location in Bangalore, India. As a consequence of rapid urbanization, Bangalore presents high local atmospheric emissions, which makes it an interesting site to study the effect of anthropogenic activities on aerosol properties. It has been found that both column (aerosol optical depth, AOD) and ground-level measurements (black carbon (BC) and composite aerosol mass) exhibit a weekly cycle with low aerosol concentrations on weekends. In comparison to the weekdays, the weekend reductions of aerosol optical depth, black carbon and composite aerosol mass concentrations were ~15%, 25% and 24%, respectively. The magnitude of weekend reduction of black carbon is as much as ~1 μg m-3. The similarity in the weekly cycle between the column and surface measurements suggests that the aerosol column loading at this location is governed by local anthropogenic emissions. The strongest weekly cycle in composite aerosol mass concentration was observed in the super micron mass range (>1 μm). The weekly cycle of composite aerosol mass in the sub micron mass range (<1 μm) was weak in comparison to the super micron aerosol mass.

  19. Theory and observations: Model simulations of the period 1955-1985

    NASA Technical Reports Server (NTRS)

    Isaksen, Ivar S. A.; Eckman, R.; Lacis, A.; Ko, Malcolm K. W.; Prather, M.; Pyle, J.; Rodhe, H.; Stordal, Frode; Stolarski, R. S.; Turco, R. P.

    1989-01-01

    The main objective of the theoretical studies presented here is to apply models of stratospheric chemistry and transport in order to understand the processes that control stratospheric ozone and that are responsible for the observed variations. The model calculations are intended to simulate the observed behavior of atmospheric ozone over the past three decades (1955-1985), for which there exists a substantial record of both ground-based and, more recently, satellite measurements. Ozone concentrations in the atmosphere vary on different time scales and for several different causes. The models described here were designed to simulate the effect on ozone of changes in the concentration of such trace gases as CFC, CH4, N2O, and CO2. Changes from year to year in ultraviolet radiation associated with the solar cycle are also included in the models. A third source of variability explicitly considered is the sporadic introduction of large amounts of NO sub x into the stratosphere during atmospheric nuclear tests.

  20. Plasma-wave observations at Uranus from Voyager 2. Progress report for period ending February 1986

    SciTech Connect

    Gurnett, D.A.; Kurth, W.S.; Scarf, F.L.; Poynter, R.L.

    1986-03-26

    Radio emissions from Uranus were detected by the Voyager 2 plasma-wave instrument about 5 days before closest approach at frequencies of 31.1 and 56.2 khz. The bow shock was identified by an abrupt broadband burst of electrostatic turbulence about 10 hours before closest approach at a radial distance of 23.5 ru. Once inside of the magnetosphere, strong whistler mode hiss and chorus emissions were observed at radial distances less than about 8 R/sub u/, in the same region where the energetic-particle instruments detected intense fluxes of energetic electrons. A variety of other plasma waves, such as (f sub c) electron-cyclotron waves, were also observed in this same region. At the ring plane crossing, the plasma wave instrument detected a large number of impulsive events that are interpreted as impacts of micron-sized dust particles on the spacecraft. The maximum impact rate was about 20 to 30 impacts/sec, and the north-south thickness of the impact region was about 4000 km. This paper presents an overview of the principal results from the plasma-wave instrument, starting with the first detection of radio emissions from Uranus, and ending a few days after closest approach.

  1. Apparent rippling with honeycomb symmetry and tunable periodicity observed by scanning tunneling microscopy on suspended graphene

    NASA Astrophysics Data System (ADS)

    Georgi, A.; Nemes-Incze, P.; Szafranek, B.; Neumaier, D.; Geringer, V.; Liebmann, M.; Morgenstern, M.

    2016-11-01

    Suspended graphene is difficult to image by scanning probe microscopy due to the inherent van der Waals and dielectric forces exerted by the tip, which are not counteracted by a substrate. Here, we report scanning tunneling microscopy data of suspended monolayer graphene in constant-current mode, revealing a surprising honeycomb structure with amplitude of 50-200 pm and lattice constant of 10-40 nm. The apparent lattice constant is reduced by increasing the tunneling current I , but does not depend systematically on tunneling voltage V or scan speed vscan. The honeycomb lattice of the rippling is aligned with the atomic structure observed on supported areas, while no atomic corrugation is found on suspended areas down to the resolution of about 3 -4 pm. We rule out that the honeycomb structure is induced by the feedback loop using a changing vscan, that it is a simple enlargement effect of the atomic lattice, as well as models predicting frozen phonons or standing phonon waves induced by the tunneling current. Although we currently do not have a convincing explanation for the observed effect, we expect that our intriguing results will inspire further research related to suspended graphene.

  2. Incidence of cancer among ferrochromium and ferrosilicon workers: an extended observation period.

    PubMed Central

    Langård, S; Andersen, A; Ravnestad, J

    1990-01-01

    Results are presented of a cohort study on the incidence of cancers and crude death rates in ferrochromium and ferrosilicon workers. The whole cohort was observed from 1 January 1953 to 31 December 1985. Two sets of results are presented; one restricted to workers first employed before 1960 and one to workers first employed before 1965. The latter cohort consists of 1235 workers. The total mortality in the whole cohort was low (SMR = 81) as was the overall incidence of cancers (SIR = 84). There was an overall deficit of deaths and cases of cancer in the ferrosilicon group. An excess of lung cancer (SIR = 154) and cancer of the prostate (SIR = 151) was observed in the ferrochromium workers employed before 1965. Cancer of the kidney was also in excess (SIR = 273) in the ferrochromium group, with a mean "latency time" of 39 years. Two cases of malignant melanomas had occurred versus 0.19 expected in a small subgroup of workers in electrical shops and an electric power station. PMID:2310703

  3. Water vapor measurements by Raman lidar during the ARM 1997 water vapor intensive observation period

    SciTech Connect

    Turner, D.D.; Whiteman, D.N.; Schwemmer, G.K.; Evans, K.D. |; Melfi, S.H.; Goldsmith, J.E.

    1998-04-01

    Water vapor is the most important greenhouse gas in the atmosphere, as it is the most active infrared absorber and emitter of radiation, and it also plays an important role in energy transport and cloud formation. Accurate, high resolution measurements of this variable are critical in order to improve the understanding of these processes and thus their ability to model them. Because of the importance of water vapor, the Department of Energy`s Atmospheric Radiation Measurement (ARM) program initiated a series of three intensive operating periods (IOPs) at its Cloud and Radiation Testbed (CART) site in northern Oklahoma. The goal of these IOPs is to improve and validate the state-of-the-art capabilities in measuring water vapor. To date, two of the planned three IOPs have occurred: the first was in September of 1996, with an emphasis on the lowest kilometer, while the second was conducted from September--October 1997 with a focus on both the upper troposphere and lowest kilometer. The ARM CART site is the home of several different water vapor measurement systems. These systems include a Raman lidar, a microwave radiometer, a radiosonde launch site, and an instrumented tower. During these IOPs, additional instrumentation was brought to the site to augment the normal measurements in the attempt to characterize the CART instruments and to address the need to improve water vapor measurement capabilities. Some of the instruments brought to the CART site include a scanning Raman lidar system from NASA/GSFC, additional microwave radiometers from NOAA/ETL, a chilled mirror that was flown on a tethersonde and kite system, and dewpoint hygrometer instruments flow on the North Dakota Citation. This paper will focus on the Raman lidar intercomparisons from the second IOP.

  4. Millimeter and some near infra-red observations of short-period Miras and other AGB stars

    NASA Astrophysics Data System (ADS)

    Groenewegen, M. A. T.; Baas, F.; Blommaert, J. A. D. L.; Stehle, R.; Josselin, E.; Tilanus, R. P. J.

    1999-12-01

    Millimeter observations of 48 oxygen- and 20 carbon-rich AGB Miras with periods shorter than 400 days are presented. In addition, observations of 14 O-rich and 15 C-stars with longer, or no known, periods have also been obtained. The detection statistics is as follows: in 12CO J=1-0 and 2-1 we observed 97 stars, and detected 66 in at least one line. We find 24 new detections in the 1-0 line, 38 new detections in the 2-1 line, and 29 stars have been detected for the first time in one or both lines. In 12CO J=3-2 we observed 14 stars and detected 11, with 4 new detections. In 13CO J=2-1, 3-2 we observed 2 stars and had one new detection. In HCN(1-0) we observed 5 carbon stars and detected 3, one new. In SO(6_5-5_4) we observed the same 5 stars and detected none. In CS(3-2) we observed 8 carbon stars and detected 3, all new. In SiO(3-2, v=0) we observed 34 O-rich stars and detected 25, all new except one. Near-infrared JHK photometry is presented for seven stars. For four stars it is the first NIR data published. The luminosity and dust mass loss rate are obtained for seven very red stars with unknown pulsation period from modelling the spectral energy distribution (SED) and IRAS LRS spectra. Thereby, a new IR supergiant is confirmed (AFGL 2968). For the rest of the sample, luminosity and distance are obtained in a variety of ways: using hipparcos parallaxes, period-luminosity and period-M_K-relations combined with apparent K magnitudes, and kinematic distances. The dust mass loss rate is obtained from model fitting of the SED (either from the literature, or presented in the present paper), or from the observed IRAS 60 mu m flux, corrected for the photospheric contribution. The gas mass loss rate is derived from the observed CO line intensities, as presented here, combined with existing literature data, if any. This allows the derivation of the dust-to-gas ratio. Our and literature CO J = 3-2 data has been used to calibrate the relation between mass loss rate and peak

  5. Observation of a periodic runaway in the reactive Ar/O{sub 2} high power impulse magnetron sputtering discharge

    SciTech Connect

    Shayestehaminzadeh, Seyedmohammad E-mail: shayesteh@mch.rwth-aachen.de; Arnalds, Unnar B.; Magnusson, Rögnvaldur L.; Olafsson, Sveinn

    2015-11-15

    This paper reports the observation of a periodic runaway of plasma to a higher density for the reactive discharge of the target material (Ti) with moderate sputter yield. Variable emission of secondary electrons, for the alternating transition of the target from metal mode to oxide mode, is understood to be the main reason for the runaway occurring periodically. Increasing the pulsing frequency can bring the target back to a metal (or suboxide) mode, and eliminate the periodic transition of the target. Therefore, a pulsing frequency interval is defined for the reactive Ar/O{sub 2} discharge in order to sustain the plasma in a runaway-free mode without exceeding the maximum power that the magnetron can tolerate.

  6. Prescription patterns of analgesics in the last 3 months of life: a retrospective analysis of 10202 lung cancer patients

    PubMed Central

    Gao, W; Gulliford, M; Higginson, I J

    2011-01-01

    Background: To describe the prescription patterns of analgesics during the last 3 months of life in lung cancer and to determine the associated factors. Methods: Data on lung cancer patients (N=10 202) who died during 2000–2008 were extracted from the General Practice Research Database (GPRD). This database records prescriptions of patients received from UK general practices (GP), but not those from non-GP routes. Prescription prevalences were estimated. The associated factors were investigated using log-binomial regression. Results: The overall prescription prevalences were 50.4% (95% confidence interval (CI): 49.4–51.4%) for level 1 (e.g., paracetamol), 34.1% (95% CI: 33.2–35.0%) for level 2 (weak opioids), and 55.5 % (95% CI: 54.5–56.4%) for level 3 analgesics (strong opioids). Prescription prevalence of analgesics of all levels showed an increasing trend over the period 2000–2008 (annual increases range: 1.1–1.5%) but a decreasing trend with age (average decrease per group range: −5.8 to −1.8%). Patients in the older age groups were less likely to be prescribed level 3 analgesics than those in the younger age groups (PR‘90+' vs ‘<50'=0.55 (95% CI: 0.45–0.67); PR‘80−89' vs ‘<50'=0.73 (95% CI: 0.66–0.79); PR‘70−79' vs ‘<50'=0.84 (95% CI: 0.77–0.90)). Conclusion: Analgesics have been increasingly prescribed in lung cancer. However, analgesics, especially at level 3, were relatively under-prescribed to people older than 70 years, warranting further investigation. PMID:21540860

  7. X-RAY AND EUV OBSERVATIONS OF SIMULTANEOUS SHORT AND LONG PERIOD OSCILLATIONS IN HOT CORONAL ARCADE LOOPS

    SciTech Connect

    Kumar, Pankaj; Cho, Kyung-Suk; Nakariakov, Valery M.

    2015-05-01

    We report decaying quasi-periodic intensity oscillations in the X-ray (6–12 keV) and extreme-ultraviolet (EUV) channels (131, 94, 1600, 304 Å) observed by the Fermi Gamma-ray Burst Monitor and Solar Dynamics Observatory/Atmospheric Imaging Assembly (AIA), respectively, during a C-class flare. The estimated periods of oscillation and decay time in the X-ray channel (6–12 keV) were about 202 and 154 s, respectively. A similar oscillation period was detected at the footpoint of the arcade loops in the AIA 1600 and 304 Å channels. Simultaneously, AIA hot channels (94 and 131 Å) reveal propagating EUV disturbances bouncing back and forth between the footpoints of the arcade loops. The period of the oscillation and decay time were about 409 and 1121 s, respectively. The characteristic phase speed of the wave is about 560 km s{sup −1} for about 115 Mm of loop length, which is roughly consistent with the sound speed at the temperature about 10–16 MK (480–608 km s{sup −1}). These EUV oscillations are consistent with the Solar and Heliospheric Observatory/Solar Ultraviolet Measurement of Emitted Radiation Doppler-shift oscillations interpreted as the global standing slow magnetoacoustic wave excited by a flare. The flare occurred at one of the footpoints of the arcade loops, where the magnetic topology was a 3D fan-spine with a null-point. Repetitive reconnection at this footpoint could have caused the periodic acceleration of non-thermal electrons that propagated to the opposite footpoint along the arcade and that are precipitating there, causing the observed 202 s periodicity. Other possible interpretations, e.g., the second harmonics of the slow mode, are also discussed.

  8. Long-period humidity variability in the Arctic atmosphere from upper-air observations

    NASA Astrophysics Data System (ADS)

    Agurenko, A.; Khokhlova, A.

    2014-12-01

    Under climate change, atmospheric water content also tends to change. This gives rise to changes in the amount of moisture transferred, clouds and precipitation, as well as in hydrological regime. This work analyzes seasonal climatic characteristics of precipitated water in the Arctic atmosphere, by using 1972-2011 data from 55 upper-air stations located north of 60°N. Regions of maximum and minimum mean values and variability trends are determined. In the summer, water amount is shown to increase in nearly the whole of the latitudinal zone. The comparison with the similar characteristics of reanalysis obtained by the other authors shows a good agreement. Time variation in the atmosphere moisture transport crossing 70°N, which is calculated from observation data, is presented and compared with model results. The work is supported by the joint EC ERA.Net RUS and Russian Fundamental Research Fund Project "Arctic Climate Processes Linked Through the Circulation of the Atmosphere" (ACPCA) (project 12-05-91656-ЭРА_а).

  9. Diurnal-period currents trapped above Fieberling Guyot: observed characteristics and model comparisons

    USGS Publications Warehouse

    Noble, M.A.; Brink, K.H.; Eriksen, C.C.

    1994-01-01

    Current measurements at depths of 19, 115, 264 and 464 m above the summit of Fieberling Guyot (32??28???N, 127??47???W) for 13 months in 1989 show that the diurnal tides are strongly amplified. The measured variances for K1, P1 and O1 at the 115 m depth were 810, 140 and 80 times larger than the variances of the respective estimated barotropic tides. The diurnal currents closer to the summit were also strongly amplified, through the variance ratios were 40-50% of the ratios observed at 115 m. The diurnal band currents were only amplified at the precise tidal frequencies; the bandwidth of the response was less than 0.0002 cph. The discrete character of the response suggests that only currents with large spatial scales will be amplified. The characteristics of the amplified diurnal currents are compared to those predicted by a model for Fieberling Guyot of seamount-trapped waves driven by the barotropic tide. The amplitudes of the responses at this one site on the seamount compare favourably to the predicted. ?? 1994.

  10. Critical appraisal of 3-monthly paliperidone depot injections in the treatment of schizophrenia

    PubMed Central

    Carpiniello, Bernardo; Pinna, Federica

    2016-01-01

    Aims Three-monthly injections of paliperidone palmitate (PP-3M) represent a new and recently introduced long-acting antipsychotic therapeutic option. This review focuses on available data relating to the efficacy and safety of PP-3M and its position in the current therapeutic scenario. Method An analysis of PubMed, Scopus, and ISI Web of Knowledge databases was conducted, and all available papers on PP-3M, including poster presentations, were selected and considered for the purpose of the present review. Findings: to date, three full papers have been published, the first, a Phase 1 randomized, open label study investigating the pharmacokinetics, safety, and tolerability of the drug; the second, a Phase 3 double blind study vs placebo focusing on efficacy and tolerability; and the last relating to the practical use of PP-3M. The five posters identified describe data reported in the above-cited papers. Overall, the pharmacokinetic findings obtained in these studies highlight the feasibility of administering PP-3M on a 3-monthly basis, subsequent to the administration of four 1-monthly injections of PP at doses 3.5 times higher than the stabilized dose of 1-monthly injections of PP (ie, 175, 300, 450, and 525 mgs). The published studies highlight a significantly longer time to relapse compared to placebo, and significantly better results compared to placebo for all secondary end-points (Positive and Negative Syndrome Scale, Clinical Global Impression-Severity Scale, Personal and Social Performance Scale scores), in addition to reasonably good safety and tolerability profiles. Conclusion PP-3M emerges as a potential candidate for use as a first-line long-acting agent in the maintenance treatment of patients with schizophrenia. Further studies should however be conducted to confirm this expectation. In view of its efficacy, tolerability, and safety, together with the longer timespan between injections, PP-3M currently represents one of the best available options, and

  11. Imaging observation of quasi-periodic disturbances' amplitudes increasing with height in the polar region of the solar corona

    SciTech Connect

    Su, J. T.; Priya, T. G.; Liu, Y.; Shen, Y. D.

    2014-08-01

    At present, there have been few extreme ultraviolet (EUV) imaging observations of spatial variations of the density perturbations due to the slow magnetoacoustic waves (SMWs) propagating along the solar coronal magnetic fields. In this paper, we present such observations taken from the polar region of the corona with the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory and investigate the amplitude of quasi-periodic propagating disturbances that increase with height in the lower corona (0-9 Mm over the solar limb). We statistically determined the following parameters associated with the disturbances: pressure scale height, period, and wavelength in AIA 171 Å, 193 Å, and 211 Å channels. The scale height and wavelength are dependent of temperature, while the period is independent of temperature. The acoustic velocities inferred from the scale height highly correlate with the ratios of wavelength to period, i.e., phase speeds. They provide evidence that the propagating disturbances in the lower corona are likely SMWs and the spatial variations in EUV intensity in the polar region likely reflects the density compressional effect by the propagating SMWs.

  12. ISEE 1 observations of thermal plasma in the vicinity of the plasmasphere during periods of quieting magnetic activity

    NASA Technical Reports Server (NTRS)

    Horwitz, J. L.; Baugher, C. R.; Chappell, C. R.; Shelley, E. G.; Young, D. T.; Anderson, R. R.

    1981-01-01

    An investigation of thermal plasma behavior in the vicinity of the plasmasphere during periods of quieting magnetic activity was conducted by combining thermal ion observations made with the plasma composition experiment on ISEE 1 with plasma density profiles obtained from plasma frequency measurements made with the same satellite's plasma wave experiment. During periods in which the magnetic activity quiets, the two regions characterized by H(+):He(+):O(+) (isotropic) and H(+):O(+):He(+) (field-aligned) ion species distributions (in order of dominance) are separated by a new region in which low-energy H(+) and He(+) are found flowing along the magnetic field lines. At other times, following quieting magnetic activity, distributions having peak fluxes at 90 deg pitch angle are observed in this region.

  13. ISEE 1 observations of thermal plasma in the vicinity of the plasmasphere during periods of quieting magnetic activity

    NASA Astrophysics Data System (ADS)

    Horwitz, J. L.; Baugher, C. R.; Chappell, C. R.; Shelley, E. G.; Young, D. T.; Anderson, R. R.

    1981-11-01

    An investigation of thermal plasma behavior in the vicinity of the plasmasphere during periods of quieting magnetic activity was conducted by combining thermal ion observations made with the plasma composition experiment on ISEE 1 with plasma density profiles obtained from plasma frequency measurements made with the same satellite's plasma wave experiment. During periods in which the magnetic activity quiets, the two regions characterized by H(+):He(+):O(+) (isotropic) and H(+):O(+):He(+) (field-aligned) ion species distributions (in order of dominance) are separated by a new region in which low-energy H(+) and He(+) are found flowing along the magnetic field lines. At other times, following quieting magnetic activity, distributions having peak fluxes at 90 deg pitch angle are observed in this region.

  14. Chemical heterogeneity in the mantle from array observations of short period P, Pdiff and their coda

    NASA Astrophysics Data System (ADS)

    Xu, Yan

    I apply array processing techniques to study the slowness and coda of P/Pdiff for 1,371 shallow earthquakes (< 200 km) that occurred in Asia, South America. Tonga-Fiji, and Indonesia, and were recorded by the medium-aperture array, YKA, in Canada. The slowness analysis shows lateral variations in Earth structure at the base of the mantle across the north Pacific. I observe an Ultra-Low Velocity Zone (ULVZ) with up to 6% P velocity reduction in this region. The ULVZ can be explained as partial melt created by disaggregated mid-ocean ridge basalt (MORE) material that was subducted many millions of year ago beneath East Asia. It is currently being swept laterally towards the large, low shear velocity province (LLSVP) in the south-central Pacific by mantle convection currents. I also measure the coda decay rate (CDR) of the P/Pdiff energy. The radial variation of the CDR suggests that more fine-scale scatterers exist in the lowermost mantle compared to the mid-mantle. The CDR also has lateral variation, with the lowermost mantle beneath subduction regions having a smaller value (decays more slowly) than that corresponding to a nonsubduction region. The lateral variations of both the slowness and the CDRs at the base of the mantle support the hypothesis that mantle convection sweeps segregated subducted MORB laterally, due to the density and the melting temperature of the MORB, and it possibly accumulates to form the LLSVP. Synthetic simulations of Pdiff coda waves using a single scattering method also prefer the whole mantle scattering model with 1% dv/v in D". The synthetic tests also constrain other important properties of the lowermost mantle. A non-smooth CMB is indicated which leads to topographical scattering, and Qp for the lowermost mantle is estimated to be quite low at 150-250.

  15. Observations and Modeling of the Near Surface Vertical Structure of the Atmosphere in the Southern Appalachians during the Integrated Precipitation and Hydrology Experiment (IPHEx) Extended Observing Period

    NASA Astrophysics Data System (ADS)

    Wilson, A. M.; Barros, A. P.

    2014-12-01

    Accurate, high resolution observations of precipitation accumulations and intensity in regions of complex terrain are largely unavailable, due to a lack of existing in situ observations and obstacles to remote sensing (radar and satellite observations) such as beam blockage and ground clutter. For the past six years, a high-elevation, high-density rain gauge network has been recording precipitation observations along ridgelines in the Pigeon River Basin in the Southern Appalachians. These longer term observations complement the 4-D database of observations, which are being collected in support of the Global Precipitation Mission (GPM) during the first field campaign after the launch of the GPM satellite, the Integrated Precipitation and Hydrology Experiment (IPHEx). The observations focused on here are those at the near surface, within 2 kilometers of the ground level. The IPHEx extended observation period lasts until the end of 2014. This presentation will focus on ground-based measurements made by MicroRain Radars, disdrometers, radiometers, rain gauges, fog collectors and aerosol spectrometers among others during the spring, summer and fall of 2014. These measurements will be analyzed to provide information on the diurnal cycle of microphysical and dynamical processes and properties in the region, with an emphasis on describing the characteristics of local cloud and fog. These observations will be discussed in the context of previous findings based on observations and model results (stochastic column model and the Advanced Research Weather and Forecasting Model (WRF)). Specifically, this presentation will address whether the IPHEx observations support the hypothesis, validated for specific case studies in previous work, that Bergeron processes govern the enhancement of light rainfall in the Southern Appalachians through increased coalescence efficiency in stratiform rainfall due to the interactions with low level clouds and topography modulated fog. WRF

  16. Local Scale Radiobrightness Modeling During the Intensive Observing Period-4 of the Cold Land Processes Experiment-1

    NASA Technical Reports Server (NTRS)

    Kim, Edward J.; Tedesco, Marco; deRoo, Roger; England, Anthony W.; Gu, Hao-Yu; Pham, Hanh; Boprie, David; Graf, Tobias; Koike, Toshio; Armstrong, Richard

    2005-01-01

    The NASA Cold Land Processes Field Experiment (CLPX-1) was designed to provide microwave remote sensing observations and ground truth for studies of snow and frozen ground remote sensing, particularly issues related to scaling. CLPX-1 was conducted in 2002 and 2003 in Colorado, USA. One of the goals of the experiment was to test the capabilities of microwave emission models at different scales. Initial forward model validation work has concentrated on the Local-Scale Observation Site (LSOS), a 0.8 ha study site consisting of open meadows separated by trees where the most detailed measurements were made of snow depth and temperature, density, and grain size profiles. Results obtained in the case of the 3& Intensive Observing Period (IOP3) period (Feb., 2003, dry snow) suggest that a model based on Dense Medium Radiative Transfer (DMRT) theory is able to model the recorded brightness temperatures using snow parameters derived from field measurements. This paper focuses on the ability of forward DMRT modelling, combined with snowpack measurements, to reproduce the radiobrightness signatures observed by the University of Michigan s Truck-Mounted Radiometer System (TMRS) at 19 and 37 GHz during the 4th IOP (IOP4) in March, 2003. Unlike IOP3, conditions during IOP4 include both wet and dry periods, providing a valuable test of DMRT model performance. In addition, a comparison will be made for the one day of coincident observations by the University of Tokyo's Ground-Based Microwave Radiometer-7 (GBMR-7) and the TMRS. The plot-scale study in this paper establishes a baseline of DMRT performance for later studies at successively larger scales. And these scaling studies will help guide the choice of future snow retrieval algorithms and the design of future Cold Lands observing systems.

  17. Local Scale Radiobrightness Modeling During the Intensive Observing Period-4 of the Cold Land Processes Experiment-1

    NASA Astrophysics Data System (ADS)

    Kim, E.; Tedesco, M.; de Roo, R.; England, A. W.; Gu, H.; Pham, H.; Boprie, D.; Graf, T.; Koike, T.; Armstrong, R.; Brodzik, M.; Hardy, J.; Cline, D.

    2004-12-01

    The NASA Cold Land Processes Field Experiment (CLPX-1) was designed to provide microwave remote sensing observations and ground truth for studies of snow and frozen ground remote sensing, particularly issues related to scaling. CLPX-1 was conducted in 2002 and 2003 in Colorado, USA. One of the goals of the experiment was to test the capabilities of microwave emission models at different scales. Initial forward model validation work has concentrated on the Local-Scale Observation Site (LSOS), a 0.8~ha study site consisting of open meadows separated by trees where the most detailed measurements were made of snow depth and temperature, density, and grain size profiles. Results obtained in the case of the 3rd Intensive Observing Period (IOP3) period (February, 2003, dry snow) suggest that a model based on Dense Medium Radiative Transfer (DMRT) theory is able to model the recorded brightness temperatures using snow parameters derived from field measurements. This paper focuses on the ability of forward DMRT modelling, combined with snowpack measurements, to reproduce the radiobrightness signatures observed by the University of Michigan's Truck-Mounted Radiometer System (TMRS) at 19 and 37~GHz during the 4th IOP (IOP4) in March, 2003. Unlike in IOP3, conditions during IOP4 include both wet and dry periods, providing a valuable test of DMRT model performance. In addition, a comparison will be made for the one day of coincident observations by the University of Tokyo's Ground-Based Microwave Radiometer-7 (GBMR-7) and the TMRS. The plot-scale study in this paper establishes a baseline of DMRT performance for later studies at successively larger scales. And these scaling studies will help guide the choice of future snow retrieval algorithms and the design of future Cold Lands observing systems.

  18. Quasi-periodic Fluctuations and Chromospheric Evaporation in a Solar Flare Ribbon Observed by Hinode/EIS, IRIS, and RHESSI

    NASA Astrophysics Data System (ADS)

    Brosius, Jeffrey W.; Daw, Adrian N.; Inglis, Andrew R.

    2016-10-01

    The Hinode/Extreme-ultraviolet Imaging Spectrometer (EIS) obtained rapid cadence (11.2 s) EUV stare spectra of an M7.3 flare ribbon in AR 12036 on 2014 April 18. Quasi-periodic (P ≈ 75.6 ± 9.2 s) intensity fluctuations occurred in emission lines of O iv, Mg vi, Mg vii, Si vii, Fe xiv, and Fe xvi during the flare's impulsive rise, and ended when the maximum intensity in Fe xxiii was reached. The profiles of the O iv-Fe xvi lines reveal that they were all redshifted during most of the interval of quasi-periodic intensity fluctuations, while the Fe xxiii profile revealed multiple components including one or two highly blueshifted ones. This indicates that the flare underwent explosive chromospheric evaporation during its impulsive rise. Fluctuations in the relative Doppler velocities were seen, but their amplitudes were too subtle to extract significant quasi-periodicities. RHESSI detected 25-100 keV hard-X-ray sources in the ribbon near the EIS slit's pointing position during the peaks in the EIS intensity fluctuations. The observations are consistent with a series of energy injections into the chromosphere by nonthermal particle beams. Electron densities derived with Fe xiv (4.6 × 1010 cm-3) and Mg vii (7.8 × 109 cm-3) average line intensity ratios during the interval of quasi-periodic intensity fluctuations, combined with the radiative loss function of an optically thin plasma, yield radiative cooling times of 32 s at 2.0 × 106 K, and 46 s at 6.3 × 105 K (about half the quasi-period); assuming Fe xiv's density for Fe xxiii yields a radiative cooling time of 103 s (13 times the quasi-period) at 1.4 × 107 K.

  19. The effect of a 3-month moderate-intensity physical activity program on body composition in overweight and obese African American college females

    PubMed Central

    Casazza, K.; Durant, N. H.

    2014-01-01

    Summary This study evaluated body composition outcomes following a 3-month exercise program for overweight/obese Black women. BMI decreased over the 3-month study despite an observed increase in body fat. Enhancements in bone marrow density and muscle density were also observed. Results show promising yet hypothesis-generating findings to explore in future research. Introduction Few studies have evaluated the relationship between aerobic physical activity (PA) and body composition among young adult overweight/obese African American (AA) women. Purpose The current study evaluated the effect of a 3-month moderate-intensity aerobic physical activity intervention for overweight and obese young adult women on bone, lean, and fat mass. Methods Participants (n=15) were a randomly selected subset of AA female college students (M age=21.7 years; M BMI= 33.3) enrolled in a larger PA promotion pilot study (n=31). Study protocol required participants to engage in four 30–60-min moderate-intensity aerobic PA sessions each week. Whole body composition was measured by dual-energy X-ray absorptiometry (DXA), and peripheral quantitative computed tomography (pQCT) was used to assess additional quantitative and qualitative assessment of the radius. Results BMI decreased over the duration of the study (P=.034), reflected by a marginal decrease in body weight (P=.057). However, unexpectedly, increases in adipose tissue measures were observed, including total body fat (P=.041), percent body fat (P=.044), trunk fat (P=.031), and percent trunk fat (P=.041). No changes in DXA-measured bone outcomes were observed (i.e., bone mineral density, P=.069; bone mineral content, P=.211). Results from the pQCT assessment showed that bone marrow density increased (P=.011), but cortical density remained stable (P=.211). A marginally significant increase in muscle density (P=.053) and no changes in muscle area (P=.776) were observed. Conclusions A 3-month moderate-intensity PA program was associated

  20. Testing the asymptotic relation for period spacings from mixed modes of red giants observed with the Kepler mission

    NASA Astrophysics Data System (ADS)

    Buysschaert, B.; Beck, P. G.; Corsaro, E.; Christensen-Dalsgaard, J.; Aerts, C.; Arentoft, T.; Kjeldsen, H.; García, R. A.; Silva Aguirre, V.; Degroote, P.

    2016-04-01

    Context. Dipole mixed pulsation modes of consecutive radial order have been detected for thousands of low-mass red-giant stars with the NASA space telescope Kepler. These modes have the potential to reveal information on the physics of the deep stellar interior. Aims: Different methods have been proposed to derive an observed value for the gravity-mode period spacing, the most prominent one relying on a relation derived from asymptotic pulsation theory applied to the gravity-mode character of the mixed modes. Our aim is to compare results based on this asymptotic relation with those derived from an empirical approach for three pulsating red-giant stars. Methods: We developed a data-driven method to perform frequency extraction and mode identification. Next, we used the identified dipole mixed modes to determine the gravity-mode period spacing by means of an empirical method and by means of the asymptotic relation. In our methodology we consider the phase offset, ɛg, of the asymptotic relation as a free parameter. Results: Using the frequencies of the identified dipole mixed modes for each star in the sample, we derived a value for the gravity-mode period spacing using the two different methods. These values differ by less than 5%. The average precision we achieved for the period spacing derived from the asymptotic relation is better than 1%, while that of our data-driven approach is 3%. Conclusions: Good agreement is found between values for the period spacing derived from the asymptotic relation and from the empirical method. The achieved uncertainties are small, but do not support the ultra-high precision claimed in the literature. The precision from our data-driven method is mostly affected by the differing number of observed dipole mixed modes. For the asymptotic relation, the phase offset, ɛg, remains ill defined, but enables a more robust analysis of both the asymptotic period spacing and the dimensionless coupling factor. However, its estimation might

  1. The reconstruction of air pressure in Gdańsk in the period of instrumental observations, 1739-2012

    NASA Astrophysics Data System (ADS)

    Filipiak, Janusz

    2015-04-01

    The purpose of the paper is to characterise the details of reconstruction of air pressure in Gdańsk in the whole period of regular instrumental records spanning the period 1739-2012. Gdańsk pressure series has been reconstructed by joining air pressure observations of 15 local shorter series. The entire instrumental series can be divided into three sub-periods: the Early Observers period, lasting to 1806, the First Meteorological Networks, covering the years from 1807 to 1875 and Modern Measurements begun in 1876. During the first period, observations were made from two to four times per day, sometimes even at midnight. In the 19th century and up to 1945 thrice-daily barometer readings were a standard, in the last few decades the density of data is much denser. A serious gap in the original daily data exists for the period 1849-1875, where it appears that no original source of data have survived. Selected data are presented in the form of five-day or monthly averages. Numerous errors made probably during the re-writing of original observers' data by their assistants were discovered during digitalization. Despite this the quality of observations can be regarded as good. Data have been corrected to provide a monthly-mean measure of atmospheric pressure in the unit of hPa at standard conditions, i.e. standard gravity, 0 °C and at sea level. Some inconsistencies may still arise as the procedure of the homogenization of air temperature is not completed and in case of a few oldest series air temperature was estimated. Numerous breakpoints were identified in the homogenisation of the series and they cannot be always linked to known causes. A reasonably detailed station history has been compiled by incorporating metadata contained in various written sources. These metadata have facilitated the homogenisation of the data series. Mean annual atmospheric pressure in Gdańsk in period 1739-2012 calculated on the basis of homogenized series was 1014.9 hPa. Mean seasonal

  2. Short-period cyclic loading system for in situ X-ray observation of anelastic properties at high pressure

    NASA Astrophysics Data System (ADS)

    Yoshino, Takashi; Yamazaki, Daisuke; Tange, Yoshinori; Higo, Yuji

    2016-10-01

    To determine the anelastic properties of materials of the Earth's interior, a short-period cyclic loading system was installed for in situ X-ray radiographic observation under high pressure to the multi-anvil deformation DIA press at the bending magnet beam line BL04B1 at SPring-8. The hydraulic system equipped with a piston controlled by a solenoid was designed so as to enable producing smooth sinusoidal stress in a wide range of oscillation period from 0.2 to 100 s and generating variable amplitudes. Time resolved X-ray radiography imaging of the sample and reference material provides their strain as a function of time during cyclic loading. A synchrotron X-ray radiation source allows us to resolve their strain variation with time even at the short period (<1 s). The minimum resolved strain is as small as 10-4, and the shortest oscillation period to detect small strain is 0.5 s. Preliminary experimental results exhibited that the new system can resolve attenuation factor Q-1 at upper mantle conditions. These results are in quantitative agreement with previously reported data obtained at lower pressures.

  3. TESTING THE NO-HAIR THEOREM WITH OBSERVATIONS IN THE ELECTROMAGNETIC SPECTRUM. III. QUASI-PERIODIC VARIABILITY

    SciTech Connect

    Johannsen, Tim; Psaltis, Dimitrios E-mail: dpsaltis@email.arizona.edu

    2011-01-01

    According to the no-hair theorem, astrophysical black holes are uniquely described by their masses and spins. An observational test of the no-hair theorem can be performed by measuring at least three different multipole moments of the spacetime of a black hole and verifying whether their values are consistent with the unique combinations of the Kerr solution. In this paper, we study quasi-periodic variability observed in the emission from black holes across the electromagnetic spectrum as a test of the no-hair theorem. We derive expressions for the Keplerian and epicyclic frequencies in a quasi-Kerr spacetime, in which the quadrupole moment is a free parameter in addition to mass and spin. We show that, for moderate spins, the Keplerian frequency is practically independent of small deviations of the quadrupole moment from the Kerr value, while the epicyclic frequencies exhibit significant variations. We apply this framework to quasi-periodic oscillations (QPOs) in black hole X-ray binaries in two different scenarios. In the case that a pair of QPOs can be identified as the fundamental g- and c-modes in the accretion disk, we show that the no-hair theorem can be tested in conjunction with an independent mass measurement. If pairs of oscillations are identified with non-parametric resonance of dynamical frequencies in the accretion disk, then testing the no-hair theorem also requires an independent measurement of the black hole spin. In addition, we argue that VLBI observations of Sgr A* may test the no-hair theorem through a combination of imaging observations and the detection of quasi-periodic variability.

  4. Investigation of the Activity of the Nucleus of Seyfert Galaxy NGC 7469 during the Observation Period from 1990 TO 2008

    NASA Astrophysics Data System (ADS)

    Ugolkova, L. S.; Artamonov, B. P.

    We combine many published photometrical observations of the Seyfert Galaxy (SG) NGC 7469 and also new results from Hubble Space Telescope which can be used for future research of some properties of the activity of the nuclear of the SG. A drift of the activity maximum from 1997 to 1998 is observed with an increased of the wave length similarly to some blazars in radio range. Analyzing the surface photometry according to data obtained both at the Maidanak observatory and HST data an intensity asymmetry at the SG central region image is observed at different periods. The existence of a second component might be supposed. The radius of the active region itself inside the SG kernel is 40-50 parsec.

  5. Feasibility of sequential adjuvant chemotherapy with a 3-month oxaliplatin-based regimen followed by 3 months of capecitabine in patients with stage III and high-risk stage II colorectal cancer: JSWOG-C2 study

    PubMed Central

    Tsuruta, Atsushi; Yamashita, Kazuki; Tanioka, Hiroaki; Tsuji, Akihito; Inukai, Michio; Yamakawa, Toshiki; Yamatsuji, Tomoki; Yoshimitsu, Masanori; Toyota, Kazuhiro; Yamano, Taketoshi; Nagasaka, Takeshi; Okajima, Masazumi

    2016-01-01

    Background Six months of oxaliplatin-based chemotherapy is the standard adjuvant chemotherapy for completely resected stage III colorectal cancer (CRC). Also, patients with stage II CRC who are considered to be at high risk of disease recurrence often receive the same adjuvant chemotherapy treatment. We prospectively investigated the extent and degree of neuropathy suffered by stage III and high-risk stage II resectable CRC patients who underwent sequential approach involving 3 months of an oxaliplatin-based regimen followed by 3 months of capecitabine. Patients and methods Patients with completely resected stage III and high-risk stage II CRC aged ≥20 years were eligible. Patients were treated with folinic acid, fluorouracil, and oxaliplatin (FOLFOX) or capecitabine and oxaliplatin (CAPOX) for 3 months followed by capecitabine (2,500 mg/m2 on days 1–14 every 3 weeks) for 3 months. Primary end points were frequency and the grade of oxaliplatin-induced neurotoxicity as evaluated using the physician-based Common Terminology Criteria for Adverse Events version 4.0 (CTCAE) grading and the patient-based scale, self-reported Patient Neurotoxicity Questionnaire. Results Ninety-one patients were enrolled and 86 patients assessed. Eighty-four percent of patients completed the planned oxaliplatin-based therapy for 3 months, and 63% of patients completed all treatments for the full 6 months. Overall incidences of grade 3 or 4 peripheral sensory or motor neuropathy according to the CTCAE were 3.5% and 1.2%, respectively. Regarding the peripheral sensory neuropathy, the proportion of Patient Neurotoxicity Questionnaire (grade C–E) and CTCAE (grade 2–4) at months 1.5/3/6 were 11.3/22.1/29.4% and 5.3/4.4/11.3%, respectively (Spearman correlation coefficient: 0.47). Conclusion A sequential approach to adjuvant chemotherapy with 3 months of an oxaliplatin-based regimen followed by 3 months of capecitabine was tolerated by patients and associated with a low incidence of

  6. Current state of the Altai glaciers (Russia) and trends over the period of instrumental observations 1952-2008.

    PubMed

    Narozhniy, Yuriy; Zemtsov, Valeriy

    2011-09-01

    Results of research into climate and glacier dynamics in the Altai Mountains (Russia) over the period of instrumental observations (1952-2008) are presented in this article. About 1030 glaciers with a total area of 805 km2 and volume of 42.5 km3 have been recorded in the Altai Region. The average summer air temperature in different regions of the Altai has increased during the study period from about 0.2 degrees C (Aktru) to 1.1 degrees C (Akkem). The annual atmospheric precipitation rate has also increased, by 8-10%. Since 1952, the glacier area in different regions of the Altai has decreased by 9-27%, and volume by 12-24%. By 2008, as a result of degradation, the total number of glaciers was 953 with an area of 724 km2 and volume of 38 km3.

  7. Observation of a periodic array of flux-closure quadrants in strained ferroelectric PbTiO3 films

    DOE PAGES

    Tang, Y. L.; Zhu, Y. L; Ma, Xiuliang; ...

    2015-05-01

    Nanoscale ferroelectrics are expected to exhibit various exotic domain configurations, such as the full flux-closure pattern that is well known in ferromagnetic materials. Here we observe not only the atomic morphology of the flux-closure quadrant but also a periodic array of flux closures in ferroelectric PbTiO3 films, mediated by tensile strain on a GdScO3 substrate. Using aberration-corrected scanning transmission electron microscopy, we directly visualize an alternating array of clockwise and counterclockwise flux closures, whose periodicity depends on the PbTiO3 film thickness. In the vicinity of the core, the strain is sufficient to rupture the lattice, with strain gradients up tomore » 109 per meter. We found engineering strain at the nanoscale may facilitate the development of nanoscale ferroelectric devices.« less

  8. Torque Ripple Suppression Control Based on the Periodic Disturbance Observer with a Complex Vector Representation for Permanent Magnet Synchronous Motors

    NASA Astrophysics Data System (ADS)

    Tadano, Yugo; Akiyama, Takao; Nomura, Masakatsu; Ishida, Muneaki

    This paper introduces a method for torque ripple suppression control involving the use of the periodic disturbance observer. By using the Fourier transform (or rotating coordinate transform and a low-pass filter), the torque ripple component, which is synchronized with the motor rotation, can easily be obtained owing to its periodic variations. With the new control method, a suppression control system synchronized with the torque ripple frequency can be built. Further, by using the system identification technique, the model system from compensating current value to torque detection value can be expressed as a speed-adjustable one-dimension complex vector in rotating coordinates. This method is suitable for an adjustable-speed drive, and the control parameters and reference model can be adjusted automatically. The most important feature of this method is its excellent performance for mechanical resonance suppression caused by torque ripple. This paper presents analysis and experimental results that validate the method.

  9. Observations and Modelling of the Pre-flare Period of the 29 March 2014 X1 Flare

    NASA Astrophysics Data System (ADS)

    Woods, M. M.; Harra, L. K.; Matthews, S. A.; Mackay, D. H.; Dacie, S.; Long, D. M.

    2017-02-01

    On 29 March 2014, NOAA Active Region (AR) 12017 produced an X1 flare that was simultaneously observed by an unprecedented number of observatories. We have investigated the pre-flare period of this flare from 14:00 UT until 19:00 UT using joint observations made by the Interface Region Imaging Spectrometer (IRIS) and the Hinode Extreme Ultraviolet Imaging Spectrometer (EIS). Spectral lines providing coverage of the solar atmosphere from the chromosphere to the corona were analysed to investigate pre-flare activity within the AR. The results of the investigation have revealed evidence of strongly blue-shifted plasma flows, with velocities up to 200 km s^{-1}, being observed 40 minutes prior to flaring. These flows are located along the filament present in the active region and are both spatially discrete and transient. In order to constrain the possible explanations for this activity, we undertake non-potential magnetic field modelling of the active region. This modelling indicates the existence of a weakly twisted flux rope along the polarity inversion line in the region where a filament and the strong pre-flare flows are observed. We then discuss how these observations relate to the current models of flare triggering. We conclude that the most likely drivers of the observed activity are internal reconnection in the flux rope, early onset of the flare reconnection, or tether-cutting reconnection along the filament.

  10. VI-band follow-up observations of ultra-long-period Cepheid candidates in M31

    SciTech Connect

    Ngeow, Chow-Choong; Yang, Michael Ting-Chang; Lin, Chi-Sheng; Hsiao, Hsiang-Yao; Cheng, Yu-Chi; Lin, Zhong-Yi; Lin, I-Ling; Ip, Wing-Huen; Lee, Chien-Hsiu; Kanbur, Shashi M.

    2015-02-01

    The ultra-long-period Cepheids (ULPCs) are classical Cepheids with pulsation periods exceeding ≈80 days. The intrinsic brightness of ULPCs are ∼1 to ∼3 mag brighter than their shorter period counterparts. This makes them attractive in future distance scale work to derive distances beyond the limit set by the shorter period Cepheids. We have initiated a program to search for ULPCs in M31, using the single-band data taken from the Palomar Transient Factory, and identified eight possible candidates. In this work, we presented the VI-band follow-up observations of these eight candidates. Based on our VI-band light curves of these candidates and their locations in the color–magnitude diagram and the Period–Wesenheit diagram, we verify two candidates as being truly ULPCs. The six other candidates are most likely other kinds of long-period variables. With the two confirmed M31 ULPCs, we tested the applicability of ULPCs in distance scale work by deriving the distance modulus of M31. It was found to be μ{sub M31,ULPC}=24.30±0.76 mag. The large error in the derived distance modulus, together with the large intrinsic dispersion of the Period–Wesenheit (PW) relation and the small number of ULPCs in a given host galaxy, means that the question of the suitability of ULPCs as standard candles is still open. Further work is needed to enlarge the sample of calibrating ULPCs and reduce the intrinsic dispersion of the PW relation before re-considering ULPCs as suitable distance indicators.

  11. Recognition of Faces and Greebles in 3-Month-Old Infants: Influence of Temperament and Cognitive Abilities

    ERIC Educational Resources Information Center

    Spangler, Sibylle M.; Freitag, Claudia; Schwarzer, Gudrun; Vierhaus, Marc; Teubert, Manuel; Lamm, Bettina; Kolling, Thorsten; Graf, Frauke; Goertz, Claudia; Fassbender, Ina; Lohaus, Arnold; Knopf, Monika; Keller, Heidi

    2011-01-01

    The aim of the present study was to investigate whether temperament and cognitive abilities are related to recognition performance of Caucasian and African faces and of a nonfacial stimulus class, Greebles. Seventy Caucasian infants were tested at 3 months with a habituation/dishabituation paradigm and their temperament and cognitive abilities…

  12. Externally Contingent and Unstable Self-Worth as Predictors of Depression in College Women: A 3-Month Study

    ERIC Educational Resources Information Center

    Lopez, Frederick G.; Thorne, Brittany; Schoenecker, Sydney; Siffert, Kevin; Chaliman, Rebecca; Castleberry, Erica

    2014-01-01

    Undergraduate women completed measures of externally contingent self-worth, self-esteem instability, and depression at the beginning (Time 1) and again 3 months later near the end (Time 2) of an academic semester. Findings indicated that when Time 1 depression scores were controlled for, each Time 1 facet of self-esteem made significant…

  13. Holistic Face Processing in Newborns, 3-Month-Old Infants, and Adults: Evidence from the Composite Face Effect

    ERIC Educational Resources Information Center

    Turati, Chiara; Di Giorgio, Elisa; Bardi, Lara; Simion, Francesca

    2010-01-01

    Holistic face processing was investigated in newborns, 3-month-old infants, and adults through a modified version of the composite face paradigm and the recording of eye movements. After familiarization to the top portion of a face, participants (N = 70) were shown 2 aligned or misaligned faces, 1 of which comprised the familiar top part. In the…

  14. Lown-Ganong-Levine syndrome in a 3-month-old infant with isolated left ventricular noncompaction.

    PubMed

    Shabanian, Reza; Kiani, Abdolrazagh; Rad, Elaheh Malakan; Eslamiyeh, Hosein

    2010-02-01

    This report describes a 3-month-old boy with isolated left ventricular noncompaction admitted to a medical facility due to heart failure and dysrhythmia. His electrocardiogram showed a short PR interval and a normal QRS complex after abortion of supraventricular tachycardia in favor of Lown-Ganong-Levine syndrome or enhanced atrioventricular nodal conduction.

  15. Search for a periodic signal from Cygnus X-3 usingmuons observed underground in the Frejus detector (4800 mwe)

    NASA Technical Reports Server (NTRS)

    Bareyre, P.; Barloutaud, R.; Becker, K. H.; Behr, L.; Berger, C.; Bland, R. W.; Chardin, G.; Daum, H. J.; Degrange, B.; Demski, S.

    1986-01-01

    Periodic signals from Cygnus X-3 in the ultra high energy range were recently reported by air shower arrays and attributed to gamma rays. Although gamma rays are expected to produce muon-poor showers, the preceding observations have stimulated similar studies based on underground muons. Two groups have claimed a significant underground signal coming from Cygnus X-3. The results are, however, extremely difficult to explain in the present framework of particle physics, and clearly need confirmation. The preliminary results obtained from the Frejus underground detector during its first 16 months of operation (March 1984 to June 1985) are presented.

  16. Variability of aerosol properties over Eastern Europe observed from ground and satellites in the period from 2003 to 2011

    NASA Astrophysics Data System (ADS)

    Bovchaliuk, A.; Milinevsky, G.; Danylevsky, V.; Goloub, P.; Dubovik, O.; Holdak, A.; Ducos, F.; Sosonkin, M.

    2013-01-01

    The paper presents the study of aerosol variability in the period from 2003 to 2011 over Eastern Europe region with latitude ranging from 40° N to 60° N and longitude from 20° E to 50° E. The analysis was based on the POLDER/PARASOL and POLDER-2/ADEOS satellites and AERONET ground-based sunphotometer observations. The aerosol optical thickness (AOT) of the studied area is characterized by the values (referenced to 870 nm wavelength) ranging from 0.05 to 0.2 except the period of July-August 2010 with strong forest and peat wildfires when the AOT typical values range from 0.3 to 0.5. The analysis of seasonal dynamics of aerosol loading has revealed two AOT high value peaks. The first peak observed in April-May is the result of solitary transportation of Sahara dust in the atmosphere over Eastern Europe, infrequent agricultural fires, transportation of sea salt aerosols by southern winds to Ukraine and Moldova from the Black and Azov Seas. The second peak in August-September is associated with forest and peat wildfires, considerable transportation of Sahara dust and presence of soil dust aerosols due to harvesting activity. The maximum values of AOT are observed in May 2006 (0.1-0.15), April 2009 (0.07-0.15) and August 2010 (0.2-0.5). Furthermore, the study has identified a distinct pattern of anthropogenic aerosols over the industrial areas, especially in the central Ukraine, eastern Belarus, as well as Moscow, Nizhny Novgorod and Stavropol regions in Russia. The comparison of the fine mode AOT (particle radius < 0.3 μm) derived by standard algorithm POLDER/PARASOL from reflected polarized radiances with those recomputed from AERONET inversions was performed over a number of AERONET sites: over Kyiv and Sevastopol sites for the period of 2008-2009 and over Moscow, Minsk, Belsk, and Moldova sites for the period of 2005-2009. The correlation coefficients are 0.78 for Moscow, 0.76 - Minsk, 0.86 - Belsk, 0.93 - Kyiv, 0.81 - Moldova and 0.63 for Sevastopol sites. The

  17. Clinical features and natural course of acromegaly in patients with discordance in the nadir GH level on the oral glucose test and the IGF-1 value at 3 months after adenomectomy.

    PubMed

    Kinoshita, Yasuyuki; Tominaga, Atsushi; Usui, Satoshi; Arita, Kazunori; Sakoguchi, Tetsuhiko; Sugiyama, Kazuhiko; Kurisu, Kaoru

    2016-04-01

    Discordant GH and IGF-1 levels after adenomectomy are well recognized in acromegalics. The aim of this study was to evaluate the clinical features and natural course of postoperative acromegaly associated with discordant GH and IGF-1 levels over a postoperative period. A total of 69 acromegalics underwent surgery with at least 1 year of follow-up and received 75-g oral glucose tolerance tests (OGTTs) at 3 months postoperatively. The patients were categorized into four groups according to the postoperative nadir GH levels and IGF-1 levels: controlled group (normal GH and normal IGF-1), high-IGF-1 group (normal GH and high IGF-1), high-GH group (high GH and normal IGF-1), and uncontrolled group (high GH and high IGF-1). The incidence of discordant GH and IGF-1 levels was 27.5%: high-IGF-1 group = 10.1% (n = 7) and high-GH group = 17.4% (n = 12). All patients in the high-IGF-1 group exhibited a decline in the IGF-1 level after surgery, with normalization observed in 71.4% of the patients without additional treatment (median 23 months). These subjects had preoperatively high IGF-1 levels despite not demonstrating higher GH levels than the patients in the controlled group. On the other hand, four patients in the high-GH group exhibited an elevated nadir GH level higher than 1.0 μg/L on repeated OGTTs after 3 months, and one patient experienced a recurrence of acromegaly. Patients in the high-IGF-1 group require no additional treatments, and their IGF-1 levels are likely to normalize within a few years. However, patients in the high-GH group should be carefully followed due to the possibility of recurrence.

  18. Plasma Neutrophil Gelatinase-Associated Lipocalin as a Marker for Prediction of 3-Month Graft Survival after Kidney Transplantation

    PubMed Central

    Jafari, A.; Khatami, M. R.; Dashti-Khavidaki, S.; Lessan-Pezeshki, M.; Abdollahi, A.

    2017-01-01

    Background: Ischemic injury during organ transplantation increases the risk of acute and chronic rejections by promoting alloimmune responses. Measurement of neutrophil gelatinase-associated lipocalin (NGAL) immediately after kidney transplantation may be promising for early detection of ischemic injuries to allograft. Objective: This study assessed possible predictive values of plasma NGAL levels during first hours after kidney transplantation for graft loss within the first 3 months after transplantation. Methods: 45 kidney transplant recipients were classified into those without graft loss or with graft loss during 3 months after transplantation. Plasma NGAL levels were measured before and at 2, 6, 12, 24 and 96 hours after transplantation. Serum creatinine concentration was assessed daily during hospitalization and at 1, 2, and 3 months post-transplantation. Results: Serum creatinine and plasma NGAL levels were consistently higher in patients with graft loss compared with those without graft loss. At 2, 24, and 96 hours after transplantation, plasma NGAL concentration was significantly higher in patients who developed allograft loss within 3 months post-transplantation. The cutoff point of plasma NGAL at 2, 24, and 96 hours after transplantation for prediction of graft loss was 304.5 ng/mL (sensitivity of 71.4%, and specificity of 73.7%), 207.8 ng/mL(sensitivity of 85.7%, and specificity of 60.5%), and 184 ng/mL (sensitivity of 85.7%, and specificity of 71.1%), respectively. Conclusion: Plasma NGAL levels at 2, 24, and 96 hours after transplantation can predict 3-month graft loss with fair sensitivity and specificity. PMID:28299024

  19. Periodicity in the occurrence of equatorial plasma bubbles derived from the C/NOFS observations in 2008-2012

    NASA Astrophysics Data System (ADS)

    Choi, Jong-Min; Kil, Hyosub; Kwak, Young-Sil; Park, Jaeheung; Lee, Woo Kyoung; Kim, Yong Ha

    2017-01-01

    The quasi-periodic occurrence of equatorial plasma bubbles is understood in terms of seeding mechanisms in the bottomside F region. However, no quantitative investigation has been conducted to identify how often quasi-periodic bubbles occur. This study investigates the wave property in the bubble occurrence (or spacing between bubbles) using the measurements of the plasma density in 2008-2012 by the Planar Langmuir Probe on board the Communication/Navigation Outage Forecasting System (C/NOFS) satellite. The wave property is investigated using the Lomb-Scargle periodograms derived from 664 segments of series of bubbles. In the majority of segments, the spacing between bubbles is represented by the combination of several wave components. Periodic bubbles whose property is represented by a few pronounced wave components are rare events. These results indicate that the spacing between bubbles is generally irregular. The manner of bubble occurrence does not show any notable variation with longitude and season. Because a consistent wave property does not exist in the occurrence of bubbles and the appearance of bubbles in the topside is affected by many factors, the manner of bubble occurrence in satellite observations does not provide a precise diagnostic of seeding mechanisms.

  20. Turbulence kinetic energy budget during the afternoon transition - Part 1: Observed surface TKE budget and boundary layer description for 10 intensive observation period days

    NASA Astrophysics Data System (ADS)

    Nilsson, Erik; Lohou, Fabienne; Lothon, Marie; Pardyjak, Eric; Mahrt, Larry; Darbieu, Clara

    2016-07-01

    The decay of turbulence kinetic energy (TKE) and its budget in the afternoon period from midday until zero-buoyancy flux at the surface is studied in a two-part paper by means of measurements from the Boundary Layer Late Afternoon and Sunset Turbulence (BLLAST) field campaign for 10 intensive observation period days. Here, in Part 1, near-surface measurements from a small tower are used to estimate a TKE budget. The overall boundary layer characteristics and mesoscale situation at the site are also described based upon taller tower measurements, radiosoundings and remote sensing instrumentation. Analysis of the TKE budget during the afternoon transition reveals a variety of different surface layer dynamics in terms of TKE and TKE decay. This is largely attributed to variations in the 8 m wind speed, which is responsible for different amounts of near-surface shear production on different afternoons and variations within some of the afternoon periods. The partitioning of near-surface production into local dissipation and transport in neutral and unstably stratified conditions was investigated. Although variations exist both between and within afternoons, as a rule of thumb, our results suggest that about 50 % of the near-surface production of TKE is compensated for by local dissipation near the surface, leaving about 50 % available for transport. This result indicates that it is important to also consider TKE transport as a factor influencing the near-surface TKE decay rate, which in many earlier studies has mainly been linked with the production terms of TKE by buoyancy and wind shear. We also conclude that the TKE tendency is smaller than the other budget terms, indicating a quasi-stationary evolution of TKE in the afternoon transition. Even though the TKE tendency was observed to be small, a strong correlation to mean buoyancy production of -0.69 was found for the afternoon period. For comparison with previous results, the TKE budget terms are normalized with

  1. Inadequacy of 3-month Oswestry Disability Index outcome for assessing individual longer-term patient experience after lumbar spine surgery.

    PubMed

    Asher, Anthony L; Chotai, Silky; Devin, Clinton J; Speroff, Theodore; Harrell, Frank E; Nian, Hui; Dittus, Robert S; Mummaneni, Praveen V; Knightly, John J; Glassman, Steven D; Bydon, Mohamad; Archer, Kristin R; Foley, Kevin T; McGirt, Matthew J

    2016-08-01

    OBJECTIVE Prospective longitudinal outcomes registries are at the center of evidence-driven health care reform. Obtaining real-world outcomes data at 12 months can be costly and challenging. In the present study, the authors analyzed whether 3-month outcome measurements sufficiently represent 12-month outcomes for patients with degenerative lumbar disease undergoing surgery. METHODS Data from 3073 patients undergoing elective spine surgery for degenerative lumbar disease were entered into a prospective multicenter registry (N(2)QOD). Baseline, 3-month, and 12-month follow-up Oswestry Disability Index (ODI) scores were recorded. The absolute differences between actual 12- and 3-month ODI scores was evaluated. Additionally, the authors analyzed the absolute difference between actual 12-month ODI scores and a model-predicted 12-month ODI score (the model used patients' baseline characteristics and actual 3-month scores). The minimal clinically important difference (MCID) for ODI of 12.8 points and the substantial clinical benefit (SCB) for ODI of 18.8 points were used based on the previously published values. The concordance rate of achieving MCID and SCB for ODI at 3-and 12-months was computed. RESULTS The 3-month ODI scores differed from 12-month scores by an absolute difference of 11.9 ± 10.8, and predictive modeling estimations of 12-month ODI scores differed from actual 12-month scores by a mean (± SD) of 10.7 ± 9.0 points (p = 0.001). Sixty-four percent of patients (n = 1982) achieved an MCID for ODI at 3 months in comparison with 67% of patients (n = 2088) by 12 months; 51% (n = 1731) and 61% (n = 1860) of patients achieved SCB for ODI at 3 months and 12 months, respectively. Almost 20% of patients had ODI scores that varied at least 20 points (the point span of an ODI functional category) between actual 3- and 12-month values. In the aggregate analysis of achieving MCID, 77% of patients were concordant and 23% were discordant in achieving or not achieving

  2. Eclipses in the Middle East from the Late Medieval Islamic Period to the Early Modern Period. Part 1: The observation of six lunar eclipses from the Late Medieval Islamic Period

    NASA Astrophysics Data System (ADS)

    Mozaffari, S. Mohammad

    2013-11-01

    This paper deals with the analysis of data obtained from observations of two sets of three lunar eclipses in the Late Medieval Islamic Period. The first trio consists of the lunar eclipses of 7 March 1262, 7 April 1270 and 24 January 1274, observed by Muḥyī al-Dīn al-Maghribī; from the Maragha Observatory (in north-western Iran), and the second includes those of 2 June and 26 November 1406, and 22 May 1407, observed by Jamshīd Ghiyāth al-Dīn al-Kāshī from Kāshān (in central Iran). The results are that al-Maghribī's values for the magnitudes of these eclipses agree excellently with modern data, and his values for the times when the maximum phases occurred agree to within five minutes with modern values. Al-Kāshī's values for the times of the maximum phases show a rather larger divergence from modern data, varying from about ten minutes to about one hour. The errors in all six values both astronomers computed from their own solar parameters for the longitude of the Sun at the instant of the opposition of the Moon to the Sun in these eclipses remain below ten minutes of arc. The motivation for doing these observations was to measure the lunar epicycle radius r in the Ptolemaic model. Al-Maghribī achieved r = 5;12 and al-Kāshī r ∼ 5;17,1 in terms of the radius of an orbit of R = 60 arbitrary units. It is argued that comparing with modern theory, neither of these two medieval values can be considered an improvement on Ptolemy's value of r = 5;15.

  3. FASTSAT-HSV01 Synergistic Observations of the Magnetospheric Response During Active Periods: MINI-ME, PISA and TTI

    NASA Technical Reports Server (NTRS)

    Casas, Joseph C.; Collier, Michael R.; Rowland, Douglas E.; Sigwarth, John B.; Boudreaux, Mark E.

    2010-01-01

    Understanding the complex processes within the inner magnetosphere of Earth particularly during storm periods requires coordinated observations of the particle and field environment using both in-situ and remote sensing techniques. In fact in order to gain a better understanding of our Heliophysics and potentially improve our space weather forecasting capabilities, new observation mission approaches and new instrument technologies which can provide both cost effective and robust regular observations of magnetospheric activity and other space weather related phenomenon are necessary. As part of the effort to demonstrate new instrument techniques and achieve necessary coordinated observation missions, NASA's Fast Affordable Science and Technology Satellite Huntsville 01 mission (FASTSAT-HSVOI) scheduled for launch in 2010 will afford a highly synergistic solution which satisfies payload mission opportunities and launch requirements as well as contributing iri the near term to our improved understanding of Heliophysics. NASA's FASTSAT-HSV01 spacecraft on the DoD Space Test Program-S26 (STP-S26) Mission is a multi-payload mission executed by the DoD Space Test Program (STP) at the Space Development and Test Wing (SDTW), Kirtland AFB, NM. and is an example of a responsive and economical breakthrough in providing new possibilities for small space technology-driven and research missions. FASTSAT-HSV is a unique spacecraft platform that can carry multiple small instruments or experiments to low-Earth orbit on a wide range of expendable launch vehicles for a fraction of the cost traditionally required for such missions. The FASTSAT-HSV01 mission allows NASA to mature and transition a technical capability to industry while increasing low-cost access to space for small science and technology (ST) payloads. The FASTSAT-HSV01 payload includes three NASA Goddard Space Flight Center (GSFC) new technology built instruments that will study the terrestrial space environment and

  4. FASTSAT-HSV01 synergistic observations of the magnetospheric response during active periods: MINI-ME, PISA and TTI

    NASA Astrophysics Data System (ADS)

    Casas, Joseph; Collier, Michael; Rowland, Douglas; Sigwarth, John; Boudreaux, Mark

    Understanding the complex processes within the inner magnetosphere of Earth particularly during storm periods requires coordinated observations of the particle and field environment using both in-situ and remote sensing techniques. In fact in order to gain a better understand-ing of our Heliophysics and potentially improve our space weather forecasting capabilities, new observation mission approaches and new instrument technologies which can provide both cost effective and robust regular observations of magnetospheric activity and other space weather related phenomenon are necessary. As part of the effort to demonstrate new instrument tech-niques and achieve necessary coordinated observation missions, NASA's Fast Affordable Sci-ence and Technology Satellite Huntsville 01 mission (FASTSAT-HSV01) scheduled for launch in 2010 will afford a highly synergistic solution which satisfies payload mission opportunities and launch requirements as well as contributing in the near term to our improved understanding of Heliophysics. NASA's FASTSAT-HSV01 spacecraft on the DoD Space Test Program-S26 (STP-S26) Mission is a multi-payload mission executed by the DoD Space Test Program (STP) at the Space Development and Test Wing (SDTW), Kirtland AFB, NM. and is an example of a responsive and economical breakthrough in providing new possibilities for small space technology-driven and research missions. FASTSAT-HSV is a unique spacecraft platform that can carry multiple small instruments or experiments to low-Earth orbit on a wide range of expendable launch vehicles for a fraction of the cost traditionally required for such missions. The FASTSAT-HSV01 mission allows NASA to mature and transition a technical capability to industry while increasing low-cost access to space for small science and technology (ST) payloads. The FASTSAT-HSV01 payload includes three NASA Goddard Space Flight Center (GSFC) new technology built instruments that will study the terrestrial space environment and

  5. High Angular Resolution Observations of Episodic Dust Emission from Long Period Variable Stars Twenty Years of Observations with the Berkeley Infrared Spatial Interferometer

    NASA Technical Reports Server (NTRS)

    Danchi, William

    2010-01-01

    Over the past twenty years the U. C. Berkeley Infrared Spatial Interferometer has observed a number of Long Period Variable stars in the mid-infrared, obtaining information on the spatial distribution of dust around these stars with resolutions of the order of a few tens of milliarcseconds. The ISI is a heterodyne interferometer operating mostly at 11.15 microns, initially with two telescopes. In the last decade, it has been taking data regularly with three telescopes, thus obtaining visibility data on three baselines and also a closure phase. Over the course of the years, the ISI has been able to measure the physical properties of the dust shells surrounding these stars, in particular the inner radii of the dust shells, as well as the temperature and density distribution. For some stars, the ISI has also made precision measurements of their diameters in the mid-infrared. Closure phase measurements have revealed asymmetries in the dust distributions around many stars. Most surprisingly the ISI data has shown evidence for substantial changes in the amount of dust on time scales of 5-10 years, rather than being directly correlated with the stellar pulsation periods, which are of the order of one year. We discuss past results and new results from the ISI that highlight the dynamic environment around these stars.

  6. Ground-based observations during the period between two strong November 2004 storms attributed to steady magnetospheric convection

    NASA Astrophysics Data System (ADS)

    Manninen, J.; Kleimenova, N. G.; Kozyreva, O. V.; Ranta, A.; Kauristie, K.; MäKinen, S.; Kornilova, T. A.

    2008-03-01

    Strong geomagnetic storms are of great scientific interest because they drive the magnetosphere to an extreme state and result in nontypical magnetosphere-ionosphere coupling. The present study examines the ground-based signatures of the magnetosphere-ionosphere disturbances during the recovery phase of the very intense storm on 7-8 November 2004. The recovery phase took place under steady and slightly negative (˜-5 nT) values of the IMF Bz. We compare this event with previously documented storm recovery phases occurring under positive IMF Bz and accompanied by morning Pc5 geomagnetic pulsations. During the period studied in this article the strongest pulsation activity was recorded in the evening and midnight sectors of the Earth. We analyze observations from the Scandinavian multipoint ground-based instrumentation: (1) geomagnetic variations and pulsations, (2) auroras in visual wavelengths, and (3) energetic particle precipitation (riometer data). We show that several enhancements in electrojet, auroral, and energetic precipitation activity were recorded at auroral latitudes. The activations lasted 0.5-2 hours, and the associated negative magnetic field deviations were often more than 1000 nT. Only one of these activations shows typical substorm behavior (poleward expansion and geostationary particle injection). We demonstrate remarkably good correlation between the magnetic variations and cosmic noise absorption variations (in pulsations and slower variations) as well as between the optical auroras and cosmic noise absorption (Imaging Riometer for Ionospheric Studies riometer system) both in time and in space. Thus the auroral precipitation revealed a very coherent behavior over a wide energy range (˜1-40 keV) during the analyzed period. The images acquired by the network of MIRACLE all-sky cameras show that the auroral distribution exhibited double oval configuration during our event. Double oval is often observed during so-called Steady Magnetospheric

  7. An overview of the lightning and atmospheric electricity observations collected in Southern France during the HYdrological cycle in Mediterranean EXperiment (HyMeX), Special Observation Period 1

    NASA Astrophysics Data System (ADS)

    Defer, E.; Pinty, J.-P.; Coquillat, S.; Martin, J.-M.; Prieur, S.; Soula, S.; Richard, E.; Rison, W.; Krehbiel, P.; Thomas, R.; Rodeheffer, D.; Vergeiner, C.; Malaterre, F.; Pedeboy, S.; Schulz, W.; Farges, T.; Gallin, L.-J.; Ortéga, P.; Ribaud, J.-F.; Anderson, G.; Betz, H.-D.; Meneux, B.; Kotroni, V.; Lagouvardos, K.; Roos, S.; Ducrocq, V.; Roussot, O.; Labatut, L.; Molinié, G.

    2014-08-01

    The PEACH (Projet en Electricité Atmosphérique pour la Campagne HyMeX - the Atmospheric Electricity Project of HyMeX Program) project is the Atmospheric Electricity component of the HyMeX (Hydrology cycle in the Mediterranean Experiment) experiment and is dedicated to the observation of both lightning activity and electrical state of continental and maritime thunderstorms in the area of the Mediterranean Sea. During the HyMeX SOP1 (Special Observation Period; 5 September-6 November 2012), four European Operational Lightning Locating Systems (OLLSs) (ATDNET, EUCLID, LINET, ZEUS) and the HyMeX Lightning Mapping Array network (HyLMA) were used to locate and characterize the lightning activity over the Southeastern Mediterranean at flash, storm and regional scales. Additional research instruments like slow antennas, video cameras, micro-barometer and microphone arrays were also operated. All these observations in conjunction with operational/research ground-based and airborne radars, rain gauges and in situ microphysical records aimed at characterizing and understanding electrically active and highly precipitating events over Southeastern France that often lead to severe flash floods. Simulations performed with Cloud Resolving Models like Meso-NH and WRF are used to interpret the results and to investigate further the links between dynamics, microphysics, electrification and lightning occurrence. A description of the different instruments deployed during the field campaign as well as the available datasets is given first. Examples of concurrent observations from radio frequency to acoustic for regular and atypical lightning flashes are then presented showing a rather comprehensive description of lightning flashes available from the SOP1 records. Then examples of storms recorded during HyMeX SOP1 over Southeastern France are briefly described to highlight the unique and rich dataset collected. Finally the next steps of the work required for the delivery of reliable

  8. Robot-Assisted Rehabilitation of Ankle Plantar Flexors Spasticity: A 3-Month Study with Proprioceptive Neuromuscular Facilitation.

    PubMed

    Zhou, Zhihao; Sun, Yao; Wang, Ninghua; Gao, Fan; Wei, Kunlin; Wang, Qining

    2016-01-01

    In this paper, we aim to investigate the effect of proprioceptive neuromuscular facilitation (PNF)-based rehabilitation for ankle plantar flexors spasticity by using a Robotic Ankle-foot Rehabilitation System (RARS). A modified robot-assisted system was proposed, and seven poststroke patients with hemiplegic spastic ankles participated in a 3-month robotic PNF training. Their impaired sides were used as the experimental group, while their unimpaired sides as the control group. A robotic intervention for the experimental group started from a 2-min passive stretching to warming-up or relaxing the soleus and gastrocnemius muscles and also ended with the same one. Then a PNF training session including 30 trials was activated between them. The rehabilitation trainings were carried out three times a week as an addition to their regular rehabilitation exercise. Passive range of motion, resistance torque, and stiffness were measured in both ankles before and after the interventions. The changes in Achilles tendon length, walking speed, and lower limb function were also evaluated by the same physician or physiotherapist for each participant. Biomechanical measurements before interventions showed significant difference between the experimental group and the control group due to ankle spasticity. For the control group, there was no significant difference in the 3 months with no robotic intervention. But for the experimental group, passive dorsiflexion range of motion increased (p < 0.01), resistance torque under different dorsiflexion angle levels (0°, 10°, and 20°) decreased (p < 0.05, p < 0.001, and p < 0.001, respectively), and quasi-static stiffness under different dorsiflexion angle levels (0°, 10°, and 20°) also decreased (p < 0.01, p < 0.001, and p < 0.001, respectively). Achilles's tendon length shortened (p < 0.01), while its thickness showed no significant change (p > 0.05). The robotic rehabilitation also improved the

  9. Factors associated with morbidity, mortality, and growth of dairy heifer calves up to 3 months of age.

    PubMed

    Windeyer, M C; Leslie, K E; Godden, S M; Hodgins, D C; Lissemore, K D; LeBlanc, S J

    2014-02-01

    Calfhood disease is an important problem on many dairy operations that can have substantial effects on heifer survival and productivity, and has economic and welfare impacts. Neonatal calf diarrhea (NCD) and bovine respiratory disease (BRD) are the most common causes of morbidity and mortality in young dairy cattle. The objective of this observational study was to investigate factors associated with the risks of morbidity and mortality, and with growth, in commercial dairy heifers calves. A total of 2874 heifer calves from 19 commercial dairy farms in Minnesota and Ontario were enrolled at 1-7 days of age and followed for approximately 3 months. Using cut-points of serum total protein of 5.2 and 5.7 g/dl, the incidences of failure of transfer of passive immunity (FTPI) were 11 and 32%, respectively. A cut-point of 5.7 g/dl was the most predictive of BRD before 5 weeks of age (sensitivity=40%, specificity=69%). The positive predictive value was poor (PPV=18%), but the negative predictive value was good (NPV=87%). A cut-point of 5.2g/dl was most predictive of death before 5 weeks of age (sensitivity=27%, specificity=89%, PPV=5%, NPV=98%). Serum total protein during the first week of life was a poor predictor of NCD. Over 23% of calves were treated for diarrhea. Risk factors were weight at enrollment, other diseases before 2 weeks of age, and an interaction between season of birth and herd-level incidence of NCD. Almost 22% of calves were treated at least once for BRD. Factors associated with an increased risk of BRD included herd-level incidence of BRD, season of birth, navel dipping, other diseases before 2 weeks of age, failure of transfer of passive immunity, and manual control of temperature in pre-weaning housing. Administration of supplemental antibody products at birth was associated with a reduced incidence of BRD. Overall mortality was 3.5%. Risk of mortality was increased by treatment for BRD and other diseases. The mean average weight gain was 0.95 kg

  10. Robot-Assisted Rehabilitation of Ankle Plantar Flexors Spasticity: A 3-Month Study with Proprioceptive Neuromuscular Facilitation

    PubMed Central

    Zhou, Zhihao; Sun, Yao; Wang, Ninghua; Gao, Fan; Wei, Kunlin; Wang, Qining

    2016-01-01

    In this paper, we aim to investigate the effect of proprioceptive neuromuscular facilitation (PNF)-based rehabilitation for ankle plantar flexors spasticity by using a Robotic Ankle–foot Rehabilitation System (RARS). A modified robot-assisted system was proposed, and seven poststroke patients with hemiplegic spastic ankles participated in a 3-month robotic PNF training. Their impaired sides were used as the experimental group, while their unimpaired sides as the control group. A robotic intervention for the experimental group started from a 2-min passive stretching to warming-up or relaxing the soleus and gastrocnemius muscles and also ended with the same one. Then a PNF training session including 30 trials was activated between them. The rehabilitation trainings were carried out three times a week as an addition to their regular rehabilitation exercise. Passive range of motion, resistance torque, and stiffness were measured in both ankles before and after the interventions. The changes in Achilles tendon length, walking speed, and lower limb function were also evaluated by the same physician or physiotherapist for each participant. Biomechanical measurements before interventions showed significant difference between the experimental group and the control group due to ankle spasticity. For the control group, there was no significant difference in the 3 months with no robotic intervention. But for the experimental group, passive dorsiflexion range of motion increased (p < 0.01), resistance torque under different dorsiflexion angle levels (0°, 10°, and 20°) decreased (p < 0.05, p < 0.001, and p < 0.001, respectively), and quasi-static stiffness under different dorsiflexion angle levels (0°, 10°, and 20°) also decreased (p < 0.01, p < 0.001, and p < 0.001, respectively). Achilles’s tendon length shortened (p < 0.01), while its thickness showed no significant change (p > 0.05). The robotic rehabilitation also improved the

  11. Variations in Electron Content Ratio and Semi-thickness Ratio during LSA and MSA periods and some Cyclone Genesis Periods using COSMIC satellite observations

    NASA Astrophysics Data System (ADS)

    Mondal, Gopal; Gupta, Manojit; Sen, Goutam Kumar

    2014-12-01

    In this study for the first time, COSMIC satellite data have been used to deduce values of ionospheric Electron Content Ratio (ECR) and Semi-thickness Ratio (Rtb) for Low Solar Activity (LSA) (2008) and Moderate Solar Activity (MSA) (2012) periods over the Indian low-latitude (15-30°N) region with 80-95°E longitude. These two ratios provide sensitive information about bottom and topside ionosphere for different geophysical conditions. Extraction of suspected patterns and discrepancies unfold that the deviations between ECR and Rtb values during LSA period are comparatively higher than that of MSA period when the diurnal variability in these two parameters is flatter along with the diurnal-dips during pre-noon hours. The correlative relationship of ECR exhibits low association with NmF2 and anti-correlation with HmF2, whereas its correlation with Rtb is extremely high. During Cyclone Genesis Period (CGP) strong dips in ECR and Rtb values with respect to pre and post CGP occurred which helps to take decisive conclusion about the ionospheric variations to be dominant through getting relatively higher Ne concentration in the bottom side part of the ionosphere.

  12. AROME-WMED, a real-time mesoscale model designed for the HyMeX Special Observation Periods

    NASA Astrophysics Data System (ADS)

    Fourrié, N.; Bresson, É.; Nuret, M.; Jany, C.; Brousseau, P.; Doerenbecher, A.; Kreitz, M.; Nuissier, O.; Sevault, E.; Bénichou, H.; Amodei, M.; Pouponneau, F.

    2015-02-01

    During autumn 2012 and winter 2013, two Special Observation Periods (SOPs) of the Hydrological cycle in the Mediterranean Experiment (HyMeX) took place. For the preparatory studies and to support the instrument deployment during the field campaign, a dedicated version of the operational convective-scale AROME-France model was developed: the AROME-WMED model. It covers the western Mediterranean basin with a 48 h forecast range. It provided real time analyses and forecasts which were sent daily to the HyMeX operational centre to forecast high precipitation events and to help decision makers on the deployment of observation instruments. This paper presents the main features of this numerical weather prediction system in terms of data assimilation and forecast. Some specific data of the HyMeX SOP were assimilated in real time. The forecast skill of the AROME-WMED is then assessed with objective scores and compared to the operational AROME-France model, for both autumn 2012 (5 September to 6 November 2012) and winter 2013 (1 February to 15 March 2013) SOPs. The overall performance of AROME-WMED is good and similar to those of AROME-France for the 0 to 30 h common forecast range. The 24 to 48 h forecast range is of course less accurate but remains useful for scheduling observation deployment. The characteristics of parameters such as precipitation, temperature or humidity, are illustrated by one heavy precipitation case study that occurred over the south of Spain.

  13. Breastfeeding Self-Efficacy Scale: Validation of the Italian Version and Correlation With Breast-feeding at 3 Months.

    PubMed

    Petrozzi, Angela; Gagliardi, Luigi

    2016-01-01

    Psychological factors can influence breast-feeding. We translated into Italian and validated the Breastfeeding Self-Efficacy Scale Short Form (BSES-SF) and investigated its predictive ability and its relation with postpartum depression symptoms.BSES-SF and Edinburgh Postnatal Depression Scale (EPDS) were administered 2 to 3 days after delivery to 122 mothers. Breast-feeding was assessed at 3 months.The BSES-SF displayed good validity (receiver operating characteristic area = 0.69) for predicting full breast-feeding at 3 months. In multivariate analysis, the probability of full breast-feeding increased 2.4% for 1-point increase of BSES-SF. The BSES-SF and EPDS scores were inversely correlated. BSES-SF is a useful tool to identify the risk of early breast-feeding attrition.

  14. Observations of the Nocturnal Boundary Layer and Morning Transitional Periods in Houston, Texas during the TexAQS II Campaign

    NASA Astrophysics Data System (ADS)

    Day, B. M.; Clements, C. B.; Rappenglueck, B.

    2007-12-01

    High-temporal resolution tethersonde profiles taken during the TexAQS II field campaign in Houston were used to study the overnight development and progression of the nocturnal boundary layer (NBL) and the evolution of the convective boundary layer after sunrise. The measurements were made at the University of Houston campus, located approximately 4 km southeast of the downtown Houston central business district, and consisted of vertical profiles of potential temperature, water vapor mixing ratio, wind speed, wind direction, and ozone concentration. Profile heights averaged 250 m AGL with a few reaching 400 m AGL. Profiles were taken at approximately 30 min intervals throughout 4 nights during Intensive Observational Periods (IOPs), including both the evening and morning transitional periods. Tethersonde experiments also were performed during several additional morning break-up periods during the campaign. Preliminary results from the overnight experiments of Sept 7-8 and Sept 14-15, 2006 showed different NBL evolutions. Sept 7-8 exhibited a stronger and deeper inversion compared with Sept 14-15 when the inversion was weak with a fairly constant height throughout the night. The Sept 7-8 profiles showed elevated bluff-like structures in the virtual potential temperature profiles between 0300-0400 CDT, indicating neutral stability within the 40-90 m AGL level. And, just before sunrise a neutral layer with constant potential temperature developed between the surface and 75 m AGL reflecting horizontal cold air advection. Further analyses will be presented for other vertical profiles taken during the campaign, including the additional overnight profiles as well as the profiles taken during the morning transition to the convective boundary layer.

  15. In the first 3 months after stroke is progressive resistance training safe and does it improve activity? A systematic review.

    PubMed

    Salter, Karen; Musovic, Amie; F Taylor, Nicholas

    2016-10-01

    BACKGROUND Progressive resistance training (PRT) can improve strength and function in people with chronic stroke, but less is known about whether this intervention is safe and beneficial during the first 3 months following stroke. OBJECTIVE To systematically review the evidence about the safety and effectiveness of PRT to improve activity in people within the first 3 months after stroke. METHODS After database searching and selection of studies a risk of bias assessment was conducted. Data for the primary outcome of safety was synthesised descriptively and meta-analyses for other outcomes were conducted using a random effects model. RESULTS The quality of the 5 included studies ranged from good to excellent (mean 24.2, range 20-28). For the trials investigating adverse events, none reported any significant increase in events after PRT. There was high level evidence that PRT had little or no effect on strength (SMD (standardized mean difference) 0.17, 95% CI -0.16 to 0.50, I(2) = 0%). There were no significant benefit for upper limb function (SMD 0.11, 95% CI -0.41 to 0.63, I(2) = 0%) and mobility (SMD 0.11, 95% CI -0.21 to 0.43, I(2) = 27%) after PRT compared with controls. CONCLUSIONS There was no evidence reported that PRT is unsafe in people within the first 3 months after stroke, although there was a lack of reporting about adverse events. The lack of demonstration of effect in improving muscle strength and activity suggests there is insufficient evidence to recommend the prescription of PRT for people within the first 3 months after stroke.

  16. Variability of aerosol properties over Eastern Europe observed from ground and satellites in the period from 2003 to 2011

    NASA Astrophysics Data System (ADS)

    Bovchaliuk, A.; Milinevsky, G.; Danylevsky, V.; Goloub, P.; Dubovik, O.; Holdak, A.; Ducos, F.; Sosonkin, M.

    2013-07-01

    The paper presents some results of the study on aerosol variability in the period from 2003 to 2011 over the Eastern Europe region, with latitude ranging from 40° N to 60° N and longitude from 20° E to 50° E. The analysis was based on the POLDER/PARASOL and POLDER-2/ADEOS satellites and AERONET (AErosol RObotic NETwork) ground-based sun photometer observations. The aerosol optical thickness (AOT) of the studied area is characterized by values (referenced to 870 nm wavelength) ranging from 0.05 to 0.2, except for in the period of July-August 2010 with strong forest and peat wildfires when the AOT typical values range from 0.3 to 0.5 according to both retrievals. The analysis of seasonal dynamics of aerosol loading has revealed two AOT high value peaks. The spring peak observed in April-May is the result of solitary transportation of Saharan dust in the atmosphere over Eastern Europe, infrequent agricultural fires, transportation of sea salt aerosols by southern winds to Ukraine and Moldova from the Black and Azov seas. The autumn peak in August-September is associated with forest and peat wildfires, considerable transportation of Saharan dust and the presence of soil dust aerosols due to harvesting activity. The maximum values of AOT are observed in May 2006 (0.1-0.15), April 2009 (0.07-0.15) and August 2010 (0.2-0.5). Furthermore, the study has identified a distinct pattern of anthropogenic aerosols over the industrial areas, especially in central Ukraine and eastern Belarus as well as Moscow region in Russia. The comparison of the AOT derived by standard algorithm POLDER/PARASOL with those recomputed from AERONET inversions for fine mode particles with radius < 0.3 μm was performed over several AERONET sites. The correlation coefficients for the POLDER/AERONET AOT retrieval comparisons are equal: 0.78 for Moscow site, 0.76 - Minsk, 0.86 - Belsk, 0.81 - Moldova (period 2005-2009), 0.93 - Kyiv and 0.63 for Sevastopol sites (2008-2009). The deviations are

  17. The OmegaWhite survey for short-period variable stars - III: follow-up photometric and spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Macfarlane, S. A.; Woudt, P. A.; Groot, P. J.; Ramsay, G.; Toma, R.; Motsoaledi, M.; Crause, L. A.; Gilbank, D. G.; O'Donoghue, D.; Potter, S. B.; Sickafoose, A. A.; van Gend, C.; Worters, H. L.

    2017-02-01

    We present photometric and spectroscopic follow-up observations of short-period variables discovered in the OmegaWhite survey, a wide-field high-cadence g-band synoptic survey targeting the Galactic Plane. We have used fast photometry on the SAAO 1.0- and 1.9-m telescopes to obtain light curves of 27 variables, and use these results to validate the period and amplitude estimates from the OmegaWhite processing pipeline. Furthermore, 57 sources (44 unique, 13 with new light curves) were selected for spectroscopic follow-up using either the SAAO 1.9-m telescope or the Southern African Large Telescope. We find that many of these variables have spectra which are consistent with being δ Scuti-type pulsating stars. At higher amplitudes, we detect four possible pulsating white dwarf/subdwarf sources and an eclipsing cataclysmic variable. Due to their rarity, these targets are ideal candidates for detailed follow-up studies. From spectroscopy, we confirm the symbiotic binary star nature of two variables identified as such in the SIMBAD database. We also report what could possibly be the first detection of the `Bump Cepheid' phenomena in a δ Scuti star, with OW J175848.21-271653.7 showing a pronounced 22 per cent amplitude dip lasting 3 min during each pulsational cycle peak. However, the precise nature of this target is still uncertain as it exhibits the spectral features of a B-type star.

  18. Vertical structure of the wind field during the Special Observing Period I of the Global Weather Experiment

    NASA Technical Reports Server (NTRS)

    Paegle, J. N.; Paegle, J.; Zhen, Z.; Sampson, G.

    1986-01-01

    The vertical structure of the global atmosphere is analyzed for selected periods of the Special Observing Period I (SOP-I) for the Global Weather Experiment (GWE). The analysis consists of projection of the stream-function and velocity potential at 200 and 850 mb on spherical harmonics and of the wind and height fields on the normal modes of a linearized form of the primitive equations for a basic state at rest. The kinematic vertical structure is discussed in terms of correlation coefficients of the 200 mb and 850 mb winds and analysis of the internal and external normal modes of the primitive equations. The reliability of the results is checked by applying the same analysis methods to data sets obtained from three different institutions: Geophysical Fluid Dynamics Laboratory (GFDL), European Center for Medium Range Weather Forecasting (ECMWF), and Goddard Laboratory for the Atmospheres (GLA). It is found that, on a global basis, vertically reversing circulations are as important as the equivalent barotropic structures. For the verticaly reversing components, the gravity and mixed Rossby-gravity modes have contributions of the same order of magnitude as those of the Rossby modes in tropical latitudes.

  19. Observation of atomic ordering of triple-period-A and -B type in GaAsBi

    SciTech Connect

    Wu, Mingjian Luna, Esperanza; Trampert, Achim; Puustinen, Janne; Guina, Mircea

    2014-07-28

    We report the observation of atomic ordering of triple-period (TP)-A and -B type in low temperature (LT) grown GaAsBi alloy using transmission electron microscopy (TEM). In addition to previous reports, where only TP-A ordering was identified in III-V alloys, here, we confirm by electron diffraction, high-resolution (HR) TEM, and HR Z-contrast scanning TEM that two ordering variants coexists for LT-GaAsBi. We find that the TP-A ordering variant dominates over the TP-B variant. TP-A domains extend over 50–100 nm (projected lateral width) and are of higher perfection compared to TP-B domains. HR Z-contrast scanning TEM on different domains reveals a variation in the Bi occupancy in the (111) planes with triple period sequence. Since the formation of ordered phases has been directly linked to the occurrence of specific surface reconstructions, our results suggest a correlation between the TP-A and B type domains and the multiple stability of n × 3 and 3 × n reconstructions on the (001) surface of GaAsBi under low temperature growth.

  20. Spectral characteristics and meridional variations of energy transformations during the first and second special observation periods of FGGE

    NASA Technical Reports Server (NTRS)

    Kung, E. C.; Tanaka, H.

    1984-01-01

    The global features and meridional spectral energy transformation variations of the first and second special observation periods of the First Global GARP Experiment (FGGE) are investigated, together with the latitudinal distribution of the kinetic energy balance. Specific seasonal characteristics are shown by the spectral distributions of the global transformations between (1) zonal mean and eddy components of the available potential energy, (2) the zonal mean and eddy components of the kinetic energy, and (3) the available potential energy and the kinetic energy. Maximum kinetic energy production is found to occur at subtropical latitudes, with a secondary maximum at higher middle latitudes. Between these two regions, there is another region characterized by the adiabatic destruction of kinetic energy above the lower troposphere.

  1. Quasi-periodic oscillations in accreting magnetic white dwarfs. II. The asset of numerical modelling for interpreting observations

    NASA Astrophysics Data System (ADS)

    Busschaert, C.; Falize, É.; Michaut, C.; Bonnet-Bidaud, J.-M.; Mouchet, M.

    2015-07-01

    Context. Magnetic cataclysmic variables are close binary systems containing a strongly magnetized white dwarf that accretes matter coming from an M-dwarf companion. The high magnetic field strength leads to the formation of an accretion column instead of an accretion disk. High-energy radiation coming from those objects is emitted from the column close to the white dwarf photosphere at the impact region. Its properties depend on the characteristics of the white dwarf and an accurate accretion column model allows the properties of the binary system to be inferred, such as the white dwarf mass, its magnetic field, and the accretion rate. Aims: We study the temporal and spectral behaviour of the accretion region and use the tools we developed to accurately connect the simulation results to the X-ray and optical astronomical observations. Methods: The radiation hydrodynamics code Hades was adapted to simulate this specific accretion phenomena. Classical approaches were used to model the radiative losses of the two main radiative processes: bremsstrahlung and cyclotron. Synthetic light curves and X-ray spectra were extracted from numerical simulations. A fast Fourier analysis was performed on the simulated light curves. The oscillation frequencies and amplitudes in the X-ray and optical domains are studied to compare those numerical results to observational ones. Different dimensional formulae were developed to complete the numerical evaluations. Results: The complete characterization of the emitting region is described for the two main radiative regimes: when only the bremsstrahlung losses and when both cyclotron and bremsstrahlung losses are considered. The effect of the non-linear cooling instability regime on the accretion column behaviour is analysed. Variation in luminosity on short timescales (~1 s quasi-periodic oscillations) is an expected consequence of this specific dynamic. The importance of secondary shock instability on the quasi-periodic oscillation

  2. Clinical management of unruptured intracranial aneurysm in Germany: a nationwide observational study over a 5-year period (2005–2009)

    PubMed Central

    Walendy, Victor; Stang, Andreas

    2017-01-01

    Objectives Our aim was to provide nationwide age-standardised rates (ASR) on the usage of endovascular coiling and neurosurgical clipping for unruptured intracranial aneurysm (UIA) treatment in Germany. Setting Nationwide observational study using the Diagnosis-Related-Groups (DRG) statistics for the years 2005–2009 (overall 83 million hospitalisations). Participants From 2005 to 2009, overall 39 155 hospitalisations with a diagnosis of UIA occurred in Germany. Primary outcome measures Age-specific and age-standardised hospitalisation rates for UIA with the midyear population of Germany in 2007 as the standard. Results Of the 10 221 hospitalisations with UIA during the observation period, 6098 (59.7%) and 4123 (40.3%) included coiling and clipping, respectively. Overall hospitalisation rates for UIA increased by 39.5% (95% CI 24.7% to 56.0%) and 50.4% (95% CI 39.6% to 62.1%) among men and women, respectively. In 2005, the ASR per 100 000 person years for coiling was 0.7 (95% CI 0.62 to 0.78) for men and 1.7 (95% CI 1.58 to 1.82) for women. In 2009, the ASR was 1.0 (95% CI 0.90 to 1.10) and 2.4 (95% CI 2.24 to 2.56), respectively. Similarly, the ASR for clipping in 2005 amounted to 0.6 (95% CI 0.52 to 0.68) for men and 1.1 (95% CI 1.00 to 1.20) for women. These rates increased in 2009 to 0.8 (95% CI 0.72 to 0.88) and 1.7 (95% CI 1.58 to 1.82), respectively. We observed a marked geographical variation of ASR for coiling and less pronounced for clipping. For the federal state of Saarland, the ASR for coiling was 5.64 (95% CI 4.76 to 6.52) compared with 0.68 (95% CI 0.48 to 0.88; per 100 000 person years) in Saxony-Anhalt, whereas, ASR for clipping were highest in Rhineland-Palatinate (2.48, 95% CI 2.17 to 4.75) and lowest in Saxony-Anhalt (0.52, 95% CI 0.34 to 0.70). Conclusions To the best of our knowledge, we presented the first representative, nationwide analysis of the clinical management of UIA in Germany. The ASR increased markedly and showed

  3. An overview of the lightning and atmospheric electricity observations collected in southern France during the HYdrological cycle in Mediterranean EXperiment (HyMeX), Special Observation Period 1

    NASA Astrophysics Data System (ADS)

    Defer, E.; Pinty, J.-P.; Coquillat, S.; Martin, J.-M.; Prieur, S.; Soula, S.; Richard, E.; Rison, W.; Krehbiel, P.; Thomas, R.; Rodeheffer, D.; Vergeiner, C.; Malaterre, F.; Pedeboy, S.; Schulz, W.; Farges, T.; Gallin, L.-J.; Ortéga, P.; Ribaud, J.-F.; Anderson, G.; Betz, H.-D.; Meneux, B.; Kotroni, V.; Lagouvardos, K.; Roos, S.; Ducrocq, V.; Roussot, O.; Labatut, L.; Molinié, G.

    2015-02-01

    The PEACH project (Projet en Electricité Atmosphérique pour la Campagne HyMeX - the Atmospheric Electricity Project of the HyMeX Program) is the atmospheric electricity component of the Hydrology cycle in the Mediterranean Experiment (HyMeX) experiment and is dedicated to the observation of both lightning activity and electrical state of continental and maritime thunderstorms in the area of the Mediterranean Sea. During the HyMeX SOP1 (Special Observation Period) from 5 September to 6 November 2012, four European operational lightning locating systems (ATDnet, EUCLID, LINET, ZEUS) and the HyMeX lightning mapping array network (HyLMA) were used to locate and characterize the lightning activity over the northwestern Mediterranean at flash, storm and regional scales. Additional research instruments like slow antennas, video cameras, microbarometer and microphone arrays were also operated. All these observations in conjunction with operational/research ground-based and airborne radars, rain gauges and in situ microphysical records are aimed at characterizing and understanding electrically active and highly precipitating events over southeastern France that often lead to severe flash floods. Simulations performed with cloud resolving models like Meso-NH and Weather Research and Forecasting are used to interpret the results and to investigate further the links between dynamics, microphysics, electrification and lightning occurrence. Herein we present an overview of the PEACH project and its different instruments. Examples are discussed to illustrate the comprehensive and unique lightning data set, from radio frequency to acoustics, collected during the SOP1 for lightning phenomenology understanding, instrumentation validation, storm characterization and modeling.

  4. Blood Pressure and Metabolic Changes After 3-Month CPAP Therapy in a Very Elderly Obese with Severe Obstructive Sleep Apnea: A Case Report and Review of the Literature.

    PubMed

    Spannella, Francesco; Giulietti, Federico; Di Pentima, Chiara; Lombardi, Francesca Elena; Borioni, Elisabetta; Sarzani, Riccardo

    2017-03-21

    Age is one of the main risk factor for the presence of obstructive sleep apnea (OSA). This syndrome is associated with hypertension, cardiovascular disease, cognitive impairment and metabolic abnormalities, such as type 2 diabetes. Continuous positive airway pressure (CPAP) represents the gold standard therapy, but its benefit is still to be determined in very elderly. We report the blood pressure and metabolic changes in a very elderly obese with severe OSA after 3-month CPAP therapy. We have evaluated a very elderly obese male affected by severe symptomatic OSA, poor controlled nocturnal hypertension and insulin resistance. After 3-month CPAP therapy, without any changes in drug therapy, we observed a normalization of circadian blood pressure (BP) pattern, an improved insulin sensitivity, together with a reduced resting energy expenditure, despite no significant change in weight. This case report shows the benefits of OSA treatment with CPAP, not only on BP profile, but also on metabolic parameters in a very elderly, a particular type of patient in which scientific evidence is still scant. Further studies are needed to better investigate the relationship between OSA, CPAP therapy and energy expenditure not only in adults but also in elderly patients.

  5. Subjective and objective observation of skin graft recovery on Indonesian local cat with different periods of transplantation time

    PubMed Central

    Erwin; Gunanti; Handharyani, Ekowati; Noviana, Deni

    2016-01-01

    Aim: The success of a skin graft in a cat is highly dependent on the granulation formed by the base of recipient bed. Granulation by the base of recipient bed will form after several days after injury. This research aimed to observe subjective and objective profile of skin graft recovery on forelimb of cats with different periods of donor skin placement. Materials and Methods: Nine male Indonesian local cats aged 1-2 years old, weighing 3-4 kg were divided into three groups. The first surgery for creating defect wound of 2 cm×2 cm in size was performed in the whole group. The wound was left for several days with the respective interval for each group, respectively: Group I (for 2 days), Group II (for 4 days), and Group III (for 6 days). In the whole group, the second surgery was done by the harvesting skin of thoracic area which then applied on recipient bed of respective groups. Result: The donor skin on Group II was accepted faster compared to Group I and Group III. The donor skin did not show color differences compared to surrounding skin, painless, bright red in bleeding test had faster both hair growth and drug absorption. Test toward the size of donor skin and the effect of drugs did not show a significant difference between each group. Conclusion: The observe subjective and objective profile of skin graft recovery on forelimb of cats on Group II were accepted faster compared to Group I and III. PMID:27284224

  6. Direct observation of single stationary-phase bacteria reveals a surprisingly long period of constant protein production activity

    PubMed Central

    Gefen, Orit; Fridman, Ofer; Ronin, Irine; Balaban, Nathalie Q.

    2014-01-01

    Exponentially growing bacteria are rarely found in the wild, as microorganisms tend to spend most of their lifetime at stationary phase. Despite this general prevalence of stationary-phase bacteria, they are as yet poorly characterized. Our goal was to quantitatively study this phase by direct observation of single bacteria as they enter into stationary phase and by monitoring their activity over several days during growth arrest. For this purpose, we devised an experimental procedure for starving single Escherichia coli bacteria in microfluidic devices and measured their activity by monitoring the production rate of fluorescent proteins. When amino acids were the sole carbon source, the production rate decreased by an order of magnitude upon entry into stationary phase. We found that, even while growth-arrested, bacteria continued to produce proteins at a surprisingly constant rate over several days. Our identification of this newly observed period of constant activity in nongrowing cells, designated as constant activity stationary phase, makes possible the conduction of assays that require constant protein expression over time, and are therefore difficult to perform under exponential growth conditions. Moreover, we show that exogenous protein expression bears no fitness cost on the regrowth of the population when starvation ends. Further characterization of constant activity stationary phase—a phase where nongrowing bacteria can be quantitatively studied over several days in a reproducible manner—should contribute to a better understanding of this ubiquitous but overlooked physiological state of bacteria in nature. PMID:24344288

  7. AROME-WMED, a real-time mesoscale model designed for the HyMeX special observation periods

    NASA Astrophysics Data System (ADS)

    Fourrié, N.; Bresson, É.; Nuret, M.; Jany, C.; Brousseau, P.; Doerenbecher, A.; Kreitz, M.; Nuissier, O.; Sevault, E.; Bénichou, H.; Amodei, M.; Pouponneau, F.

    2015-07-01

    During autumn 2012 and winter 2013, two special observation periods (SOPs) of the HYdrological cycle in the Mediterranean EXperiment (HyMeX) took place. For the preparatory studies and to support the instrument deployment during the field campaign, a dedicated version of the operational convective-scale Application of Research to Operations at Mesoscale (AROME)-France model was developed: the AROME-WMED (West Mediterranean Sea) model. It covers the western Mediterranean basin with a 48 h forecast range. It provided real-time analyses and forecasts which were sent daily to the HyMeX operational centre to forecast high-precipitation events and to help decision makers on the deployment of meteorological instruments. This paper presents the main features of this numerical weather prediction system in terms of data assimilation and forecast. Some specific data of the HyMeX SOP were assimilated in real time. The forecast skill of AROME-WMED is then assessed with objective scores and compared to the operational AROME-France model, for both autumn 2012 (05 September to 06 November 2012) and winter 2013 (01 February to 15 March 2013) SOPs. The overall performance of AROME-WMED is good for the first HyMeX special observation period (SOP1) (i.e. mean 2 m temperature root mean square error (RMSE) of 1.7 °C and mean 2 m relative humidity RMSE of 10 % for the 0-30 h forecast ranges) and similar to those of AROME-France for the 0-30 h common forecast range (maximal absolute difference of 2 m temperature RMSE of 0.2 °C and 0.21 % for the 2 m relative humidity); conversely, for the 24-48 h forecast range it is less accurate (relative loss between 10 and 12 % in 2 m temperature and relative humidity RMSE, and equitable threat score (ETS) for 24 h accumulated rainfall), but it remains useful for scheduling observation deployment. The characteristics of parameters, such as precipitation, temperature or humidity, are illustrated by one heavy precipitation case study that occurred

  8. TIME DELAYS IN QUASI-PERIODIC PULSATIONS OBSERVED DURING THE X2.2 SOLAR FLARE ON 2011 FEBRUARY 15

    SciTech Connect

    Dolla, L.; Marque, C.; Seaton, D. B.; Dominique, M.; Berghmans, D.; Cabanas, C.; De Groof, A.; Verdini, A.; West, M. J.; Zhukov, A. N.; Van Doorsselaere, T.; Schmutz, W.; Zender, J.

    2012-04-10

    We report observations of quasi-periodic pulsations (QPPs) during the X2.2 flare of 2011 February 15, observed simultaneously in several wavebands. We focus on fluctuations on timescale 1-30 s and find different time lags between different wavebands. During the impulsive phase, the Reuven Ramaty High Energy Solar Spectroscopic Imager channels in the range 25-100 keV lead all the other channels. They are followed by the Nobeyama RadioPolarimeters at 9 and 17 GHz and the extreme-ultraviolet (EUV) channels of the Euv SpectroPhotometer (ESP) on board the Solar Dynamic Observatory. The zirconium and aluminum filter channels of the Large Yield Radiometer on board the Project for On-Board Autonomy satellite and the soft X-ray (SXR) channel of ESP follow. The largest lags occur in observations from the Geostationary Operational Environmental Satellite, where the channel at 1-8 A leads the 0.5-4 A channel by several seconds. The time lags between the first and last channels is up to Almost-Equal-To 9 s. We identified at least two distinct time intervals during the flare impulsive phase, during which the QPPs were associated with two different sources in the Nobeyama RadioHeliograph at 17 GHz. The radio as well as the hard X-ray channels showed different lags during these two intervals. To our knowledge, this is the first time that time lags are reported between EUV and SXR fluctuations on these timescales. We discuss possible emission mechanisms and interpretations, including flare electron trapping.

  9. Climatology of Mid-Latitude Mstid Events Observed by the Demeter Satellite in the Period 2005-2010.

    NASA Astrophysics Data System (ADS)

    Berthelier, J. J.; Nguyen, C. T.; Amory-Mazaudier, C. C.; Petitdidier, M.

    2015-12-01

    Using plasma measurements from the CNES DEMETER micro-satellite, we have performed a global survey of ionospheric disturbances observed at middle and low latitudes on the nightime part of the DEMETER orbit in the local time sector 21.30-22.30 LT. This study encompasses the 6 years of the satellite operations, from 2005 to 2010, including years of moderate magnetic activity of solar cycles 23 and 24 and the deep solar minimum in 2009-2010. We report in this poster a statistical analysis of MSTID events characterized by quasi-periodic variations of the O+ density observed below ~ 40° geomagnetic latitudes with wavelengths ranging from 350 to 700 km. Although detected in both hemispheres they occur predominantly at southern latitudes with a rather strong peak over the Pacific ocean. A detailed analysis has shown that these events may be sorted in 4 categories according to their latitudinal extent. Most of them are restricted to a latitude band between ~ 15° and 40° geomagnetic in North or South but some of them extend from mid latitudes in one hemisphere to low latitude in the other hemisphere, thus spanning equatorial regions up to 5-10°. The apparent negative correlation with magnetic activity seems to indicate that most of these events are driven by AGW originating from low altitude atmospheric levels and not triggered by auroral phenomena. We shall present the seasonal and inter-annual variations showing significant changes associated with solar activity. Our results will be compared to other ground-based or satellite observations and our investigation pointed out a strong effect of these MSTID and their parent AGW on the electrodynamics of the low latitude ionosphere.

  10. The quasi-biennial periodicity (QBP) in velocity and intensity helioseismic observations. The seismic QBP over solar cycle 23

    NASA Astrophysics Data System (ADS)

    Simoniello, R.; Finsterle, W.; Salabert, D.; García, R. A.; Turck-Chièze, S.; Jiménez, A.; Roth, M.

    2012-03-01

    Aims: We looked for signatures of quasi-biennial periodicity (QBP) over different phases of solar cycle by means of acoustic modes of oscillation. Low-degree p-mode frequencies are shown to be sensitive to changes in magnetic activity due to the global dynamo. Recently there has been reported evidence of two-year variations in p-mode frequencies. Methods: Long high-quality helioseismic data are provided by BiSON (Birmingham Solar Oscillation Network), GONG (Global Oscillation Network Group), GOLF (Global Oscillation at Low Frequency) and VIRGO (Variability of Solar IRradiance and Gravity Oscillation) instruments. We determined the solar cycle changes in p-mode frequencies for spherical degree ℓ = 0, 1, 2 with their azimuthal components in the frequency range 2.5 mHz ≤ ν ≤ 3.5 mHz. Results: We found signatures of QBP at all levels of solar activity in the modes more sensitive to higher latitudes. The signal strength increases with latitude and the equatorial component also seems to be modulated by the 11-year envelope. Conclusions: The persistent nature of the seismic QBP is not observed in the surface activity indices, where mid-term variations are found only from time to time and mainly in periods of high activity. This feature, together with the latitudinal dependence, provides more evidence of a mechanism that is almost independent and different from the one that brings the active regions up to the surface. Therefore, these findings can be used to provide more constraints on dynamo models that consider a further cyclic component on top of the 11-year cycle.

  11. Observations of Atmospheric Nitrogen and Phosphorus Deposition During the Period of Algal Bloom Formation in Northern Lake Taihu, China

    NASA Astrophysics Data System (ADS)

    Zhai, Shuijing; Yang, Longyuan; Hu, Weiping

    2009-09-01

    Cyanobacterial blooms in Lake Taihu occurred at the end of April 2007 and had crucial impacts on the livelihood of millions of people living there. Excessive nutrients may promote bloom formation. Atmospheric nitrogen (N) and phosphorus (P) deposition appears to play an important role in algal bloom formation. Bulk deposition and rain water samples were collected respectively from May 1 to November 30, 2007, the period of optimal algal growth, to measure the bulk atmospheric deposition rate, wet deposition rate, and dry deposition rate for total nitrogen (TN; i.e., all species of nitrogen), and total phosphorus (TP; i.e., all species of phosphorus), in northern Lake Taihu, China. The trends of the bulk atmospheric deposition rate for TN and the wet deposition rate for TN showed double peaks during the observation period and distinct influence with plum rains and typhoons. Meanwhile, monthly bulk atmospheric deposition rates for TP showed little influence of annual precipitation. However, excessive rain may lead to high atmospheric N and P deposition rates. In bulk deposition samples, the average percentage of total dissolved nitrogen accounting for TN was 91.2% and changed little with time. However, the average percentage of total dissolved phosphorus accounting for TP was 65.6% and changed substantially with time. Annual bulk atmospheric deposition rates of TN and TP during 2007 in Lake Taihu were estimated to be 2,976 and 84 kg km-2 a-1, respectively. The results showed decreases of 34.4% and 78.7%, respectively, compared to 2002-2003. Annual bulk deposition load of TN for Lake Taihu was estimated at 6,958 t a-1 in 2007 including 4,642 t a-1 of wet deposition, lower than the values obtained in 2002-2003. This may be due to measures taken to save energy and emission control regulations in the Yangtze River Delta. Nevertheless, high atmospheric N and P deposition loads helped support cyanobacterial blooms in northern Lake Taihu during summer and autumn, the period

  12. [Effect of 3-month exercise training on daily energy expenditure in formerly obese women with reduced and stable weight].

    PubMed

    Buemann, B; Astrup, A V

    1993-06-14

    Predisposition to obesity has been suggested to be related to a low energy expenditure (EE). This condition could be counteracted by physical exercise. In the present study we wanted to elucidate if aerob training could increase sedentary 24-hour energy expenditure in formerly obese subjects. Seven reduced-obese premenopausal women were studied in a respiration chamber before and after a three month period of aerobic training. No significant effects of training were seen on daytime, sleeping or total 24-hour EE. However, the change in daytime EE was positively correlated to the change in VO2max. Sleeping and 24-hour respiratory quotients were slightly increased after the training period. In order to reveal a possible role of the sympathetic nervous system in the observed effect of training, additional experiments were performed with beta blockade. However, no interactions between training and beta blockade were found.

  13. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays

    PubMed Central

    Amin, Hayder; Maccione, Alessandro; Marinaro, Federica; Zordan, Stefano; Nieus, Thierry; Berdondini, Luca

    2016-01-01

    The recent availability of human induced pluripotent stem cells (hiPSCs) holds great promise as a novel source of human-derived neurons for cell and tissue therapies as well as for in vitro drug screenings that might replace the use of animal models. However, there is still a considerable lack of knowledge on the functional properties of hiPSC-derived neuronal networks, thus limiting their application. Here, upon optimization of cell culture protocols, we demonstrate that both spontaneous and evoked electrical spiking activities of these networks can be characterized on-chip by taking advantage of the resolution provided by CMOS multielectrode arrays (CMOS-MEAs). These devices feature a large and closely-spaced array of 4096 simultaneously recording electrodes and multi-site on-chip electrical stimulation. Our results show that networks of human-derived neurons can respond to electrical stimulation with a physiological repertoire of spike waveforms after 3 months of cell culture, a period of time during which the network undergoes the expression of developing patterns of spontaneous spiking activity. To achieve this, we have investigated the impact on the network formation and on the emerging network-wide functional properties induced by different biochemical substrates, i.e., poly-dl-ornithine (PDLO), poly-l-ornithine (PLO), and polyethylenimine (PEI), that were used as adhesion promoters for the cell culture. Interestingly, we found that neuronal networks grown on PDLO coated substrates show significantly higher spontaneous firing activity, reliable responses to low-frequency electrical stimuli, and an appropriate level of PSD-95 that may denote a physiological neuronal maturation profile and synapse stabilization. However, our results also suggest that even 3-month culture might not be sufficient for human-derived neuronal network maturation. Taken together, our results highlight the tight relationship existing between substrate coatings and emerging network

  14. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays.

    PubMed

    Amin, Hayder; Maccione, Alessandro; Marinaro, Federica; Zordan, Stefano; Nieus, Thierry; Berdondini, Luca

    2016-01-01

    The recent availability of human induced pluripotent stem cells (hiPSCs) holds great promise as a novel source of human-derived neurons for cell and tissue therapies as well as for in vitro drug screenings that might replace the use of animal models. However, there is still a considerable lack of knowledge on the functional properties of hiPSC-derived neuronal networks, thus limiting their application. Here, upon optimization of cell culture protocols, we demonstrate that both spontaneous and evoked electrical spiking activities of these networks can be characterized on-chip by taking advantage of the resolution provided by CMOS multielectrode arrays (CMOS-MEAs). These devices feature a large and closely-spaced array of 4096 simultaneously recording electrodes and multi-site on-chip electrical stimulation. Our results show that networks of human-derived neurons can respond to electrical stimulation with a physiological repertoire of spike waveforms after 3 months of cell culture, a period of time during which the network undergoes the expression of developing patterns of spontaneous spiking activity. To achieve this, we have investigated the impact on the network formation and on the emerging network-wide functional properties induced by different biochemical substrates, i.e., poly-dl-ornithine (PDLO), poly-l-ornithine (PLO), and polyethylenimine (PEI), that were used as adhesion promoters for the cell culture. Interestingly, we found that neuronal networks grown on PDLO coated substrates show significantly higher spontaneous firing activity, reliable responses to low-frequency electrical stimuli, and an appropriate level of PSD-95 that may denote a physiological neuronal maturation profile and synapse stabilization. However, our results also suggest that even 3-month culture might not be sufficient for human-derived neuronal network maturation. Taken together, our results highlight the tight relationship existing between substrate coatings and emerging network

  15. Postnatal depression among Sudanese women: prevalence and validation of the Edinburgh Postnatal Depression Scale at 3 months postpartum

    PubMed Central

    Khalifa, Dina Sami; Glavin, Kari; Bjertness, Espen; Lien, Lars

    2015-01-01

    Purpose Postnatal depression (PND) rates in low-resource countries have reached levels between 4.9% and 59%. Maternal mental health has not been researched in Sudan, and there are no existing statistics on prevalence or significant risk factors for PND. Consequently, no screening test has been validated to screen for PND at the primary health care level. This study investigates the 3 months prevalence of PND and validates the Edinburgh Postnatal Depression Scale (EPDS) against the Mini-International Neuropsychiatric Interview (MINI). Methodology Pregnant Sudanese women in the second and third trimesters were recruited to the study during routine antenatal care visits in two major maternity hospitals in Khartoum state. They were screened for PND at 3 months postpartum using the EPDS. Test positive women were matched with test negative women according to nearest date of birth. A clinical psychologist verified their depression status using the MINI. Results The follow-up rate was 79%. At a cutoff point of ≥12, the 3 months prevalence of PND was 9.2%. The sensitivity and specificity of the EPDS were 89% and 82%, respectively. The EPDS and MINI showed a strong positive relationship (odds ratio =36). The positive predictive value and negative predictive value, using this study’s prevalence, were 33% and 98.7%, respectively. The receiver operator characteristic analysis showed an area under the curve of 0.89. The cut-off point ≥12 was the most acceptable point as it had the lowest number needed to diagnose (1.4) and a false-positive rate of 18%. Conclusion The EPDS is a valid tool for screening for PND on a Sudanese population. It was accepted, easily administered, and understood by postnatal women. Health care personnel, especially village midwives, should be trained on screening and referral of depressed women for clinical evaluation and management. Due to limited resources available in Sudan, shorter screening tests need to be validated in the future. PMID

  16. Bipolar radiofrequency ablation of benign thyroid nodules using a multiple overlapping shot technique in a 3-month follow-up.

    PubMed

    Kohlhase, Konstantin David; Korkusuz, Yücel; Gröner, Daniel; Erbelding, Christian; Happel, Christian; Luboldt, Wolfgang; Grünwald, Frank

    2016-08-01

    Purpose The aim of this study was to evaluate the decrease of benign thyroid nodules after bipolar radiofrequency ablation (RFA) in a 3-month follow-up using a multiple overlapping shot technique ('MOST'). Methods A total of 18 patients with 20 symptomatic benign thyroid nodules (17 cold nodules, 3 hyperfunctioning nodules) were treated in one single session by bipolar RFA. Bipolar ablation was performed using MOST. The nodule volumes were measured prior to ablation and 3 months after the procedure using ultrasound. The population consisted of either solid (>80% solid tissue within the volume of interest), complex, or cystic nodules (<20% solid tissue within the volume of interest). Results Bipolar RFA resulted in a highly significant (p < 0.0001) decrease of nodule volume (ΔV), median 5.3 mL (range 0.13-43.1 mL), corresponding to a relative reduction in mean of 56 ± 17.9%. Median initial volume was 8 mL (range 0.48-62 mL); 3 months after ablation a median volume of 2.3 mL (range 0.3-32 mL) was measured. Nodule growth ≥50% occurred in 70% (14 nodules). At the follow-up no complications such as infections, persisting pain, nerve injuries or immunogen stimulation occurred. Patients with cold nodules (15) remained euthyroid, with hyperfunctioning nodules either euthyroid (2) or latent hypofunctional (1). Conclusion The use of bipolar RFA is an effective, safe and suitable thermoablative technique to treat benign thyroid nodules. Combined with the multiple overlapping shot technique it allows sufficient ablation.

  17. Cosmogenic 7Be and 22Na in Finland: Production, observed periodicities and the connection to climatic phenomena

    NASA Astrophysics Data System (ADS)

    Leppänen, A.-P.; Usoskin, I. G.; Kovaltsov, G. A.; Paatero, J.

    2012-01-01

    This study presents theoretical production calculations and time series analyses of two cosmogenic isotopes, 7Be and 22Na, from the four high-latitude stations of Kotka, Kajaani, Rovaniemi and Ivalo located in Finland. We used published results for 7Be but performed full simulations of the 22Na production in atmosphere. For the first time, lookup tables of 22Na production by cosmic rays in the atmosphere are presented. In conjunction with calculations using the new model of 22Na production, the 7Be/22Na ratios in the atmosphere were also calculated. The wavelet transform of the 7Be and 22Na time series revealed sets of periodicities in the 2.5-8 year range. The wavelet coherence method was used to study coherences between 7Be and 22Na and 7Be/22Na data and AO, NAO, AMO, QBO and SO teleconnection indices representing different climatic variations in Northern Europe. In the wavelet coherence analyses, the 7Be activities were found to be mainly modulated by NAO and AMO at an interannual scale, while 22Na activity was found to be less effected by climatic phenomena. The 7Be coherence with other indices was intermittent where the coherence with SO was limited to Ivalo data and in the case of QBO, to Kotka data. The 22Na data was not found to be in coherence with any of the studied indices. In the 7Be/22Na ratio a clear seasonal pattern was observed where low 7Be/22Na ratios were observed during summer and high ratios during winter. This was speculated to be caused by the height of atmospheric vertical mixing. During 2006-2011, the 7Be/22Na ratios from Kotka, Kajaani and Rovaniemi showed variance at synoptic time scales but were nearly identical at the seasonal scale. The 7Be/22Na ratio was proposed to be a radiochronometer to estimate residence times of aerosols carrying 7Be and 22Na.

  18. New EMA report on paliperidone 3-month injections: taking clinical and policy decisions without an adequate evidence base.

    PubMed

    Ostuzzi, G; Papola, D; Gastaldon, C; Barbui, C

    2016-12-22

    Three-month long-acting paliperidone is a new, recently marketed, formulation of paliperidone, characterised by the longest available dosing interval among long-acting antipsychotics. The clinical profile of 3-month long-acting paliperidone was recently summarised by the European Medicines Agency (EMA) in a public assessment report, released in April 2016. In this commentary, the main strengths and limitations of the EMA assessment report were appraised and discussed, in order to highlight possible implications for clinical practice, future research and regulatory practices for drug approval.

  19. Traumatic dissecting aneurysm at the vertebrobasilar junction in a 3-month-old infant: evaluation and treatment strategies. Case report.

    PubMed

    Wang, Huan; Orbach, Darren B

    2008-05-01

    Intracranial aneurysms in young infants are extremely rare, with few published reports on the etiology, evaluation, treatment strategies, and follow-up of this condition in this population. The authors report the case of a traumatic dissecting aneurysm at the vertebrobasilar junction (VBJ) in a 3-month-old infant caused by nonaccidental trauma. Therapeutic occlusion of the VBJ was contemplated, but coil embolization of the main aneurysm sac proved feasible, and anticoagulation and antiplatelet agents were initiated. The patient made a full neurological recovery, and follow-up studies demonstrated stable aneurysm occlusion. Management and follow-up strategies for this challenging condition are discussed.

  20. A Low Baseline Glomerular Filtration Rate Predicts Poor Clinical Outcome at 3 Months after Acute Ischemic Stroke

    PubMed Central

    Kim, Hyung Jik; Kim, Jwa-Kyung; Oh, Mi Sun; Kim, Sung Gyun; Yu, Kyung-Ho

    2015-01-01

    Background and Purpose Chronic kidney disease (CKD) is an established risk factor for numerous cardiovascular diseases including stroke. The relationship between the baseline estimated glomerular filtration rate (eGFR) and clinical 3-month outcomes in patients with acute ischemic stroke were evaluated in this study. Methods This was a prospective cohort study involving a hospital-based stroke registry; 1373 patients with acute ischemic stroke were enrolled. Patients were divided into the following four groups according their eGFR (calculated using the CKD Epidemiology Collaboration equations): ≥60, 45-59, 30-44, and <30 mL/min/1.73 m2. The primary endpoint of poor functional outcome was defined as 3-month death or dependency (modified Rankin Scale score ≥3); secondary endpoints were neurological deterioration (increase in National Institutes of Health Stroke Severity score of ≥4 at discharge compared to baseline) during hospitalization and in-hospital mortality. Results The overall eGFR was 84.5±20.8 mL/min/1.73 m2 (mean±SD). The distribution of baseline renal impairment was as follows: 1,218, 82, 40, and 33 patients had eGFRs of ≥60, 45-59, 30-44, and <30 mL/min/1.73 m2, respectively. At 3 months after the stroke, 476 (34.7%) patients exhibited poor functional outcome. Furthermore, a poor functional outcome occurred more frequently with increasingly advanced stages of CKD (rates of 31.9%, 53.7%, 55.0%, and 63.6% for CKD stages 1/2, 3a, 3b, and 4/5, respectively; p<0.001). Multivariate analysis revealed that a baseline eGFR of <30 mL/min/1.73m2 increased the risk of a poor functional outcome by 2.37-fold (p=0.047). In addition, baseline renal dysfunction was closely associated with neurological deterioration during hospitalization and with in-hospital mortality. Conclusions A low baseline eGFR was strongly predictive of both poor functional outcome at 3 months after ischemic stroke and neurological deterioration/mortality during hospitalization. PMID

  1. Microbiological and biochemical effectiveness of an antiseptic gel on the bacterial contamination of the inner space of dental implants: a 3-month human longitudinal study.

    PubMed

    D'Ercole, S; Tetè, S; Catamo, G; Sammartino, G; Femminella, B; Tripodi, D; Spoto, G; Paolantonio, M

    2009-01-01

    Microbial penetration inside the implants internal cavity produces a bacterial reservoir that is associated with an area of inflamed connective tissue facing the fixture-abutment junction. The aim of this clinical trial is to evaluate the effectiveness of a 1 percent chlorhexidine gel on the internal bacterial contamination of implants with screw-retained abutments and on the level of AST secreted in peri-implant crevicular fluid. Twenty-five patients (aged 29 to 58 years) each received one implant. Three months after the end of the restorative treatment, and immediately after a clinical and radiographic examination and the abutment removal, microbiological samples were obtained from the internal part of each fixture and biochemical samples were collected by peri-implant sulci. The patients were then divided into two groups: the control (CG; n=10) and test (TG; n=15) groups. The CG had the abutment screwed into place and the crown cemented without any further intervention. In contrast, before the abutment placement and screw tightening, the TG had the internal part of the fixture filled with a 1 percent chlorhexidine gel. Three months later, the same clinical, microbiological and biochemical procedures were repeated in both groups. Total bacterial count, specific pathogens and AST activity were detected. The clinical parameters remained stable throughout the study. From baseline to the 3-month examination, the total bacterial counts underwent a significant reduction only in the TG. In contrast, the AST activity showed a significant increase in the CG. The administration of a 1% chlorhexidine gel appears to be an effective method for the reduction of bacterial colonization of the implant cavity and for safeguarding the health status of peri-implant tissue over a 3-month administration period.

  2. In situ observations of the basal angiosperm Amborella trichopoda reveal a long fruiting cycle overlapping two annual flowering periods.

    PubMed

    Fourcade, Fanny; Pouteau, Robin; Jaffré, Tanguy; Marmey, Philippe

    2015-09-01

    Amborella trichopoda is the sole living angiosperm species belonging to the sister lineage of all other extant flowering plants. In the last decade, the species has been the focus of many phylogenetic, genomic and reproductive biology studies, bringing new highlights regarding the evolution of flowering plants. However, little attention has been paid to in situ A. trichopoda populations, particularly to their fruiting cycle. In this study, an A. trichopoda population was observed during three annual flowering cycles. Individuals and branches were labeled in order to monitor the fruiting cycle precisely, from the flowering stage until the abscission of the fruit. Fruit exocarp was green during the first 9 months following flowering, turned red when the next flowering started a year later then remained on the branch during another year, between fruit ripping and abscission. Presence of fruits with two stages of maturity on shrubs was always noticed. Germination tests showed that seeds acquired their germination capacity 1 year after flowering, when fruits changed color. A. trichopoda's fruiting cycle is a long process overlapping two annual flowering periods. These results introduce a new model for flowering and fruiting cycles. The availability of mature seeds on shrubs for more than 1 year is likely to maximize opportunities to be dispersed, thus promoting the survival of this basal angiosperm.

  3. Remote Cloud Sensing Intensive Observation Period (RCS-IOP) millimeter-wave radar calibration and data intercomparison

    SciTech Connect

    Sekelsky, S.M.; Firda, J.M.; McIntosh, R.E.

    1996-04-01

    During April 1994, the University of Massachusetts (UMass) and the Pennsylvania State University (Penn State) fielded two millimeter-wave atmospheric radars in the Atmospheric Radiation Measurement Remote Cloud Sensing Intensive Operation Period (RCS-IOP) experiment. The UMass Cloud Profiling Radar System (CPRS) operates simultaneously at 33.12 GHz and 94.92 GHz through a single antenna. The Penn State radar operates at 93.95 GHz and has separate transmitting and receiving antennas. The two systems were separated by approximately 75 meters and simultaneously observed a variety of cloud types at verticle incidence over the course of the experiment. This abstract presents some initial results from our calibration efforts. An absolute calibration of the UMass radar was made from radar measurements of a trihedral corner reflector, which has a known radar cross-section. A relative calibration of between the Penn State and UMass radars is made from the statistical comparison of zenith pointing measurements of low altitude liquid clouds. Attenuation is removed with the aid of radiosonde data, and the difference in the calibration between the UMass and Penn State radars is determined by comparing the ratio of 94-GHz and 95-GHz reflectivity values to a model that accounts for parallax effects of the two antennas used in the Penn State system.

  4. Comparison of Columnar Water Vapor Measurements During The Fall 1997 ARM Intensive Observation Period: Solar Transmittance Methods

    NASA Technical Reports Server (NTRS)

    Schmid, B.; Michalsky, J. J.; Slater, D. W.; Barnard, J. C.; Halthore, R. N.; Liljegren, J. C.; Holben, B. N.; Eck, T. F.; Livingston, J. M.; Russell, P. B.

    2000-01-01

    In the fall of 1997, during an Intensive Observation Period (IOP), the Atmospheric Radiation Measurement (ARM) program conducted a study of water vapor abundance measurement at its Southern Great Plains (SGP) site. Among a large number of instruments, four sun-tracking radiometers were present to measure the columnar water vapor (CWV). All four solar radiometers retrieve CWV by measuring total solar transmittance in the 0.94-gm water vapor absorption band and subtracting contributions due to Rayleigh, ozone and aerosol transmittances. The aerosol optical depth comparisons among the same four radiometers has been presented elsewhere (Geophys. Res. Lett., 26, 17, 2725-2728, 1999). We have used three different methods to retrieve CWV. In a first round of comparison no attempt was made to standardize on the same radiative transfer model and its underlying water vapor spectroscopy. In the second round of comparison we used the same line-by-line code (which includes recently corrected H2O spectroscopy) to retrieve CAN from all four suntracking radiometers. This decreased the mean CWV by 8% or 13%. The spread of 8% in the solar radiometer results found when using the same model is an indication of the other-than-model uncertainties involved in determining CWV from solar transmittance measurements with current instrumentation.

  5. Intestinal stoma in patients with colorectal cancer from the perspective of 20-year period of clinical observation

    PubMed Central

    Banaszkiewicz, Zbigniew; Woda, Łukasz P.; Tojek, Krzysztof; Jarmocik, Paweł; Jawień, Arkadiusz

    2015-01-01

    Introduction Intestinal stoma is a procedure most often performed in patients with colorectal cancer. Aim To identify the percentage of patients with colorectal cancer in which the intestinal stoma was performed. Material and methods We retrospectively analysed 443 patients treated during a 20-year period (1994–2013) due to colorectal cancer, in which the intestinal stoma was made during the first surgical intervention. Results In the second analysed decade, a significant decrease in the percentage of created stomas, definitive stomas in particular, was observed. Stomas were made significantly more often in patients with a tumour located in the rectum, the left half of the colon, and in patients undergoing urgent surgeries. An increased incidence of intestinal stomas was associated with a higher severity of illness and higher proportion of unresectable and non-radical procedures. The definitive stomas were significantly more often made in men and in patients with tumours located in the rectum, whereas temporary stomas were created significantly more often in patients undergoing urgent operations. Conclusions In the last decade (2004–2013) the number of intestinal stomas in patients operated due to colorectal cancer was significantly reduced. PMID:25960811

  6. The HyMeX Special Observation Period in Central Italy: Precipitation Measurements, Retrieval Techniques and Preliminary Results

    NASA Technical Reports Server (NTRS)

    Gatlin, Patrick; Wingo, Matt; Petersen, Walt; Marzano, Frank Silvio; Baldini, Luca; Picciotti, Errico; Colantonio, Matteo; Barbieri, Stefano; Di Fabio, Saverio; Montopoli, Mario; Roberto, Nicoletta; Adirosi, Elisa; Gorgucci, Eugenio; Anagnostou, Emmanoil N..; Ferretti, Rossella

    2013-01-01

    The Mediterranean area concentrates the major natural risks related to the water cycle, including heavy precipitation and flash-flooding during the fall season. The capability to predict such high-impact events remains weak because of the contribution of very fine-scale processes and their non-linear interactions with the larger scale processes. These societal and science issues motivate the HyMeX (Hydrological cycle in the Mediterranean Experiment, http://www.hymex.orgl) experimental programme. HyMeX aims at a better quantification and understanding of the water cycle in the Mediterranean with emphasis on intense events. The observation strategy of HyMEX is organized in a long-term (4 years) Enhanced Observation Periods (EOP) and short-term (2 months) Special Observation Periods (SOP). HyMEX has identified 3 main Mediterranean target areas: North-West (NW), Adriatic (A) and South-East (SE). Within each target area several hydrometeorological sites for heavy rainfall and flash flooding have been set up. The hydrometeorological sire in Central Italy (CI) is interested by both western and eastern fronts coming from the Atlantic Ocean and Siberia, respectively. Orographic precipitations play an important role due to the central Apennine range, which reaches nearly 3000 m (Gran Sasso peak). Moreover, convective systems commonly develop in CI during late summer and beginning of autumn, often causing localized hailstorms with cluster organized cells. Western fronts may heavily hit the Tiber basin crossing large urban areas (Rome), whereas eastern fronts can cause flash floods along the Adriatic coastline. Two major basins are involved within Cl region: Tiber basin (1000 km long) and its tributary Aniene and the Aterno-Pescara basin (300 km long). The first HyMeX SOP1.1 was carried out from Sept. till Nov. 2012 in the NW target area The Italian SOP1.1 was coordinated by the Centre of Excellence CETEMPS, University of L'Aquila, a city located in the CI heart. The CI area

  7. The origins of word learning: Brain responses of 3-month-olds indicate their rapid association of objects and words.

    PubMed

    Friedrich, Manuela; Friederici, Angela D

    2017-03-01

    The present study explored the origins of word learning in early infancy. Using event-related potentials (ERP) we monitored the brain activity of 3-month-old infants when they were repeatedly exposed to several initially novel words paired consistently with each the same initially novel objects or inconsistently with different objects. Our results provide strong evidence that these young infants extract statistic regularities in the distribution of the co-occurrences of objects and words extremely quickly. The data suggest that this ability is based on the rapid formation of associations between the neural representations of objects and words, but that the new associations are not retained in long-term memory until the next day. The type of brain response moreover indicates that, unlike in older infants, in 3-month-olds a semantic processing stage is not involved. Their ability to combine words with meaningful information is caused by a primary learning mechanism that enables the formation of proto-words and acts as a precursor for the acquisition of genuine words.

  8. OBSERVATIONAL STUDY OF THE QUASI-PERIODIC FAST-PROPAGATING MAGNETOSONIC WAVES AND THE ASSOCIATED FLARE ON 2011 MAY 30

    SciTech Connect

    Shen Yuandeng; Liu Yu

    2012-07-01

    On 2011 May 30, quasi-periodic fast-propagating (QFP) magnetosonic waves accompanied by a C2.8 flare were directly imaged by the Atmospheric Imaging Assembly instrument on board the Solar Dynamics Observatory. The QFP waves successively emanated from the flare kernel, they propagated along a cluster of open coronal loops with a phase speed of {approx}834 km s{sup -1} during the flare's rising phase, and the multiple arc-shaped wave trains can be fitted with a series of concentric circles. We generate the k - {omega} diagram of the Fourier power and find a straight ridge that represents the dispersion relation of the waves. Along the ridge, we find a lot of prominent nodes which represent the available frequencies of the QFP waves. On the other hand, the frequencies of the flare are also obtained by analyzing the flare light curves using the wavelet technique. The results indicate that almost all the main frequencies of the flare are consistent with those of the QFP waves. This suggests that the flare and the QFP waves were possibly excited by a common physical origin. On the other hand, a few low frequencies (e.g., 2.5 mHz (400 s) and 0.7 mHz (1428 s)) revealed by the k - {omega} diagram cannot be found in the accompanying flare. We propose that these low frequencies were possibly due to the leakage of the pressure-driven p-mode oscillations from the photosphere into the low corona, which should be a noticeable mechanism for driving the QFP waves observed in the corona.

  9. Detecting multiple periodicities in observational data with the multifrequency periodogram - I. Analytic assessment of the statistical significance

    NASA Astrophysics Data System (ADS)

    Baluev, Roman V.

    2013-11-01

    We consider the `multifrequency' periodogram, in which the putative signal is modelled as a sum of two or more sinusoidal harmonics with independent frequencies. It is useful in cases when the data may contain several periodic components, especially when their interaction with each other and with the data sampling patterns might produce misleading results. Although the multifrequency statistic itself was constructed earlier, for example by G. Foster in his CLEANest algorithm, its probabilistic properties (the detection significance levels) are still poorly known and much of what is deemed known is not rigorous. These detection levels are nonetheless important for data analysis. We argue that to prove the simultaneous existence of all n components revealed in a multiperiodic variation, it is mandatory to apply at least 2n - 1 significance tests, among which most involve various multifrequency statistics, and only n tests are single-frequency ones. The main result of this paper is an analytic estimation of the statistical significance of the frequency tuples that the multifrequency periodogram can reveal. Using the theory of extreme values of random fields (the generalized Rice method), we find a useful approximation to the relevant false alarm probability. For the double-frequency periodogram, this approximation is given by the elementary formula (π/16)W2e- zz2, where W denotes the normalized width of the settled frequency range, and z is the observed periodogram maximum. We carried out intensive Monte Carlo simulations to show that the practical quality of this approximation is satisfactory. A similar analytic expression for the general multifrequency periodogram is also given, although with less numerical verification.

  10. Pulsations and Period Changes of the Non-Blazhko RR Lyrae Variable Y Oct Observed from Dome A, Antarctica

    NASA Astrophysics Data System (ADS)

    Huang, Zhihua; Fu, Jianning; Zong, Weikai; Wang, Lingzhi; Macri, Lucas M.; Wang, Lifan; Ashley, Michael C. B.; Cui, Xiangqun; Feng, Long-Long; Gong, Xuefei; Lawrence, Jon S.; Liu, Qiang; Luong-Van, Daniel; Pennypacker, Carl R.; Yang, Huigen; Yuan, Xiangyan; York, Donald; Xu, Zhou; Zhu, Zhenxi; Zhu, Zonghong

    2015-01-01

    During the operation of the Chinese Small Telescope Array (CSTAR) in Dome A of Antarctica in the years 2008, 2009, and 2010, large amounts of photometric data have been obtained for variable stars in the CSTAR field. We present here the study of one of six RR Lyrae variables, Y Oct, observed with CSTAR in Dome A, Antarctica. Photometric data in the i band were obtained in 2008 and 2010, with a duty cycle (defined as the fraction of time representing scientifically available data to CSTAR observation time) of about 44% and 52%, respectively. In 2009, photometric data in the g and r bands were gathered for this star, with a duty cycle of 65% and 60%, respectively. Fourier analysis of the data in the three bands only shows the fundamental frequency and its harmonics, which is characteristic of the non-Blazhko RR Lyrae variables. Values of the fundamental frequency and the amplitudes, as well as the total pulsation amplitude, are obtained from the data in the three bands separately. The amplitude of the fundamental frequency and the total pulsation amplitude in the g band are the largest, and those in the i band the smallest. Two-hundred fifty-one times of maximum are obtained from the three seasons of data, which are analyzed together with 38 maximum times provided in the GEOS RR Lyrae database. A period change rate of -0.96 ± 0.07 days Myr-1 is then obtained, which is a surprisingly large negative value. Based on relations available in the literature, the following physical parameters are derived: [Fe/H] = -1.41 ± 0.14, MV = 0.696 ± 0.014 mag, V-K = 1.182 ± 0.028 mag, log {{T}eff} = 3.802 ± 0.003 K, log g = 2.705 ± 0.004, log L/{{L}⊙ } = 1.625 ± 0.013, and log M/{{M}⊙ } = -0.240 ± 0.019.

  11. Pulsations and period changes of the non-Blazhko RR lyrae variable Y oct observed from Dome A, Antarctica

    SciTech Connect

    Zhihua, Huang; Jianning, Fu; Weikai, Zong; Lingzhi, Wang; Zonghong, Zhu; M, Macri Lucas; Lifan, Wang; Ashley, Michael C. B.; S, Lawrence Jon; Daniel, Luong-Van; Xiangqun, Cui; Long-Long, Feng; Xuefei, Gong; Qiang, Liu; Huigen, Yang; Xiangyan, Yuan; Xu, Zhou; Zhenxi, Zhu; R, Pennypacker Carl; G, York Donald

    2015-01-01

    During the operation of the Chinese Small Telescope Array (CSTAR) in Dome A of Antarctica in the years 2008, 2009, and 2010, large amounts of photometric data have been obtained for variable stars in the CSTAR field. We present here the study of one of six RR Lyrae variables, Y Oct, observed with CSTAR in Dome A, Antarctica. Photometric data in the i band were obtained in 2008 and 2010, with a duty cycle (defined as the fraction of time representing scientifically available data to CSTAR observation time) of about 44% and 52%, respectively. In 2009, photometric data in the g and r bands were gathered for this star, with a duty cycle of 65% and 60%, respectively. Fourier analysis of the data in the three bands only shows the fundamental frequency and its harmonics, which is characteristic of the non-Blazhko RR Lyrae variables. Values of the fundamental frequency and the amplitudes, as well as the total pulsation amplitude, are obtained from the data in the three bands separately. The amplitude of the fundamental frequency and the total pulsation amplitude in the g band are the largest, and those in the i band the smallest. Two-hundred fifty-one times of maximum are obtained from the three seasons of data, which are analyzed together with 38 maximum times provided in the GEOS RR Lyrae database. A period change rate of −0.96 ± 0.07 days Myr{sup −1} is then obtained, which is a surprisingly large negative value. Based on relations available in the literature, the following physical parameters are derived: [Fe/H] = −1.41 ± 0.14, M{sub V} = 0.696 ± 0.014 mag, V−K = 1.182 ± 0.028 mag, logT{sub eff} = 3.802 ± 0.003 K, logg = 2.705 ± 0.004, logL/L{sub ⊙} = 1.625 ± 0.013, and logM/M{sub ⊙} = −0.240 ± 0.019.

  12. Stable time patterns of railway suicides in Germany: comparative analysis of 7,187 cases across two observation periods (1995–1998; 2005–2008)

    PubMed Central

    2014-01-01

    Background The majority of fatalities on the European Union (EU) railways are suicides, representing about 60% of all railway fatalities. The aim of this study was to compare time patterns of suicidal behaviour on railway tracks in Germany between two observation periods (1995–1998 and 2005–2008) in order to investigate their stability and value in railway suicide prevention. Methods Cases were derived from the National Central Registry of person accidents on the German railway network (STABAG). The association of daytime, weekday and month with the mean number of suicides was analysed applying linear regression. Potential differences by observation period were assessed by adding observation period and the respective interaction terms into the linear regression. A 95% confidence interval for the mean number of suicides was computed using the t distribution. Results A total of 7,187 railway suicides were recorded within both periods: 4,102 (57%) in the first period (1995–1998) and 3,085 (43%) in the second (2005–2008). The number of railway suicides was highest on Mondays and Tuesdays in the first period with an average of 3.2 and 3.5 events and of 2.6 events on both days in the second period. In both periods, railway suicides were more common between 6:00 am and noon, and between 6:00 pm and midnight. Seasonality was only prominent in the period 1995–1998. Conclusions Over the course of two observation periods, the weekday and circadian patterns of railway suicides remained stable. Therefore, these patterns should be an integral part of railway suicide preventive measures, e.g. gatekeeper training courses. PMID:24498876

  13. Elementary school children's responses 3 months after the September 11 terrorist attacks: a study in Washington, DC.

    PubMed

    Phillips, Deborah; Prince, Shantay; Schiebelhut, Laura

    2004-10-01

    This study examined the responses of elementary school children in Washington, DC, to the September 11 terrorist attacks. Parents (primarily mothers) of children in kindergarten through Grade 6 and children in Grades 4 to 6, including 47 matched parent-child pairs, completed questionnaires regarding exposure, stress reactions, and constructive actions taken 3 months after the attacks. Parent reports and, to an even greater extent, children's self-reports revealed high levels of negative reactions to the attacks on behalf of the children. These reactions were best understood in the context of their exposure to the attacks, primarily through television news, and the reactions of and coping assistance provided by their parents. Implications for school personnel, health care professionals, and intervention efforts are discussed.

  14. Idiopathic bilateral chronic subdural hematoma with left internal carotid artery infarct in a 3 months infant: A rare case report

    PubMed Central

    Kumar, Mahesh; Yadav, Krishan; Verma, Saurabh Kumar; Maheshwari, Vikas

    2016-01-01

    Spontaneous chronic subdural hematoma (CSH) in infants is extremely rare. A very limited number of cases are known and reported in literature. The clinical presentation can be myriad varying from asymptomatic cases to gross neurological deficits. We report a case of a 3-month-old child who presented to us with repeated episodes of focal seizures of the left upper and lower limb of 1 month duration. Subsequent imaging revealed bilateral CSH (right > left) with left internal carotid artery infarct and midline shift to left by 8 mm. The child improved following burr hole evacuation of the right-sided CSH. The management of such case and a brief review of literature are discussed. PMID:28217168

  15. A 3-month intervention of Dance Dance Revolution improves interference control in elderly females: a preliminary investigation.

    PubMed

    Chuang, Lan-Ya; Hung, Hsiao-Yun; Huang, Chung-Ju; Chang, Yu-Kai; Hung, Tsung-Min

    2015-04-01

    Exercise regimens suitable to the elderly remain under investigated; therefore, this study examined the effects of Dance Dance Revolution (DDR) on cognitive control in elderly females. Twenty-six healthy elderly females leading a sedentary lifestyle were assigned to a DDR, brisk walking, or control group. Participants in the DDR and brisk walking groups engaged in moderate physical exercise three times per week for 3 months, whereas the control group maintained a sedentary lifestyle. Each participant performed a flanker task before and after the intervention. The results revealed that both DDR and brisk walking shortened reaction time, N2 latency, and P3 latency relative to those of the control group. These findings suggest that DDR intervention is as effective as that of brisk walking in improving inhibitory control for elderly people. Therefore, DDR can be used as a viable alternative exercise to enhance cognitive function for the elderly and motivate individuals who are less willing to be active.

  16. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 5: A 3-month study of extrinsic tooth staining, northeast USA.

    PubMed

    Bosma, M L; Besho, R W; Walley, D; Mankodi, S; Petrone, M E; Chaknis, P; DeVizio, W; Volpe, A R; Proskin, H M

    1997-01-01

    The objective of this 3-month, double-blind clinical study was to investigate the level of tooth staining associated with the use of Colgate Optimized Stannous Fluoride (COSF) dentifrice compared to the tooth staining associated with two commercially available dentifrices. The results of this clinical study support the conclusion that the intensity and extent of extrinsic tooth stain associated with the use of the COSF dentifrice are significantly lower than that associated with Crest Gum Care Toothpaste. Further, this study provided no indication that the use of the COSF dentifrice is associated with a greater level of stain than that associated with the use of Crest Regular Toothpaste, a standard 0.243% sodium fluoride/silica dentifrice.

  17. Dynamics of CO2-exchange and C-budgets due to soil erosion: Insights from a 4 years observation period

    NASA Astrophysics Data System (ADS)

    Hoffmann, Mathias; Albiac Borraz, Elisa; Garcia Alba, Juana; Augustin, Jürgen; Sommer, Michael

    2015-04-01

    Agriculture in the hummocky ground moraine landscape of NE-Germany is characterized by an increase in energy crop cultivation, like maize or sorghum. Both enhance lateral C fluxes by erosion and induce feedbacks on C dynamics of agroecosystems as a result of reduced wintertime plant cover and vigorous crop growth during summer. However, the actual impact of these phenomena on the CO2-sink/-source function of agricultural landscapes, is still not clear. Therefore, the interdisciplinary project "CarboZALF" was established in Dedelow/Prenzlau (NE-Germany) in 2009. Within the field experiment CarboZALF-D, CO2 fluxes for the soil-plant systems were monitored, covering typical landscape relevant soil states in respect to erosion and deposition, like Calcic Cutanic Luvisol and Endogleyic Colluvic Regosol. Automated chamber systems, each consisting of four transparent chambers (2.5 m height, basal area 2.25 m2), were placed along gradients at both measurement sites. Monitored CO2 fluxes were gap-filled on a high-temporal resolution by modelling ecosystem respiration (Reco), gross primary productivity (GPP) and net ecosystem exchange (NEE) based on parallel and continuous measurements of the CO2 exchange, soil and air temperatures as well as photosynthetic active radiation (PAR). Gap-filling was e.g. needed in case of chamber malfunctions and abrupt disturbances by farming practice. The monitored crop rotation was corn-winter wheat (2 a), sorghum-winter triticale and alfalfa (1.5 a). In our presentation we would like to show insights from a 4 years observation period, with prounounced differences between the eroded and the colluvial soil: The Endogleyic Colluvic Regosol showed higher flux rates for Reco, GPP and NEE compared to the Calcic Cutanic Luvisol. Site-specific NEE and C-balances were positively related to soil C-stocks as well as biomass production, and generated a minor C-sink in case of the Calcic Cutanic Luvisol and a highly variable C-source in case of the

  18. Enhanced cued fear memory following post-training whole body irradiation of 3-month-old mice.

    PubMed

    Olsen, Reid H J; Weber, Sydney J; Akinyeke, Tunde; Raber, Jacob

    2017-02-15

    Typically, in studies designed to assess effects of irradiation on cognitive performance the animals are trained and tested for cognitive function following irradiation. Little is known about post-training effects of irradiation on cognitive performance. In the current study, 3-month-old male mice were irradiated with X-rays 24h following training in a fear conditioning paradigm and cognitively tested starting two weeks later. Average motion during the extinction trials, measures of anxiety in the elevated zero maze, and body weight changes over the course of the study were assessed as well. Exposure to whole body irradiation 24h following training in a fear conditioning resulted in greater freezing levels 2 weeks after training. In addition, motion during both contextual and cued extinction trials was lower in irradiated than sham-irradiated mice. In mice trained for cued fear conditioning, activity levels in the elevated zero maze 12days after sham-irradiation or irradiation were also lower in irradiated than sham-irradiated mice. Finally, the trajectory of body weight changes was affected by irradiation, with lower body weights in irradiated than sham-irradiated mice, with the most profound effect 7days after training. These effects were associated with reduced c-Myc protein levels in the amygdala of the irradiated mice. These data indicate that whole body X ray irradiation of mice at 3 months of age causes persistent alterations in the fear response and activity levels in a novel environment, while the effects on body weight seem more transient.

  19. Early Prediction of 3-month Survival of Patients in Refractory Cardiogenic Shock and Cardiac Arrest on Extracorporeal Life Support

    PubMed Central

    Delmas, Clément; Conil, Jean-Marie; Sztajnic, Simon; Georges, Bernard; Biendel, Caroline; Dambrin, Camille; Galinier, Michel; Minville, Vincent; Fourcade, Olivier; Silva, Stein; Marcheix, Bertrand

    2017-01-01

    Background: Extracorporeal life support (ECLS) holds the promise of significant improvement of the survival of patient in refractory cardiogenic shock (CS) or cardiac arrest (CA). Nevertheless, it remains to be shown to which extent these highly invasive supportive techniques could improve long-term patient's outcome. Methods: The outcomes of 82 adult ECLS patients at our institution between January 2012 and December 2013 were retrospectively analyzed. Results: Patients were essentially men (64.7%) and are 54 years old. Preexisting ischemic (53.7%) and dilated cardiomyopathy (14.6%) were frequent. ECLS indications were shared equally between CA and CS. ECLS-specific adverse effects as hemorrhage (30%) and infection (50%) were frequent. ECLS was effective for 43 patients (54%) with recovery for 35 (43%), 5 (6%) heart transplant, and 3 (4%) left ventricular assist device support. Mortality rate at 30 days was 59.8%, but long-term and 3-month survival rates were similar of 31.7%. Initial plasma lactate levels >5.3 mmol/L and glomerular filtration rate <43 ml/min/1.73 m2 were significantly associated with 3-month mortality (risk ratio [RR] 2.58 [1.21–5.48]; P = 0.014; RR 2.10 [1.1–4]; P = 0.024, respectively). Long-term follow-up had shown patients paucisymptomatic (64% New York Heart Association 1–2) and autonomic (activities of daily living [ADL] score 6 ± 1.5). Conclusion: In case of refractory CA or CS, lactates and renal function at ECLS initiation could serve as outcome predictor for risk stratification and ECLS indication.

  20. Changes in blood pressure, heart rate, and blood profile in mares during the last 3 months of gestation and the peripartum period.

    PubMed

    Nagel, Christina; Trenk, Lisa; Aurich, Jörg; Wulf, Manuela; Aurich, Christine

    2016-10-15

    In this study, peripartum changes in complete blood count, plasma electrolyte concentrations, blood pressure, heart rate, and heart rate variability (HRV) were determined in pregnant Warmblood mares (n = 10). Blood was collected from Days 245 to 330 of gestation (phase A), 2Days 3 to 1 before foaling (phase B), repeatedly within 12 hours after foaling (phase C), and on Days 1 to 3 postpartum (phase D). On the same days as blood collection, blood pressure and cardiac beat-to-beat intervals were measured and time domain HRV variables were calculated. Blood pressure decreased during the past 3 months of gestation, reached a nadir at foaling and increased rapidly thereafter (P < 0.001). Heart rate increased in phase A, reached a maximum in phase B, and decreased directly after foaling (P < 0.001) while HRV increased transiently after foaling (P < 0.001). The number of polymorphonuclear granulocytes was higher during phases B, C, and D than that during phase A (P < 0.001) and total leukocyte numbers peaked in phase C (P < 0.001). Erythrocyte counts and hematocrit increased immediately after foaling with a rapid decrease thereafter (P < 0.001), while plasma total protein was highest 1 hour after foaling (P < 0.001). Sodium and chloride concentrations increased from phases A to C and decreased in phase D (P < 0.001). Calcium concentrations were lowest immediately after foaling. In conclusion, changes in cardiovascular function and a transient hemoconcentration occur in peripartum mares. These changes may favor adequate uterine perfusion.

  1. Observations of Periodic Comet 2P/Encke: Physical Properties of the Nucleus and First Visual-Wavelength Detection of Its Dust Trail

    NASA Technical Reports Server (NTRS)

    Lowry, Stephen C.; Weissman, Paul R.; Sykes, Mark V.; Reach, William T.

    2003-01-01

    We are conducting an observational program designed to determine the overall distributions of size, shape, rotation period, and surface characteristics of cometary nuclei. Here, we present results from a study of the Jupiter- family comet 2P/Encke based on observations from Steward Observatory's 2.3m Bok Telescope at Kitt Peak. This comet has been observed extensively in the past and was one of the primary flyby targets of the recently failed CONTOUR mission.

  2. Superorbital Periodic Modulation in Wind-Accretion High-Mass X-Ray Binaries from Swift Burst Alert Telescope Observations

    NASA Technical Reports Server (NTRS)

    Corbet, Robin H. D.; Krimm, Hans A.

    2013-01-01

    We report the discovery using data from the Swift-Burst Alert Telescope (BAT) of superorbital modulation in the wind-accretion supergiant high-mass X-ray binaries 4U 1909+07 (= X 1908+075), IGR J16418-4532, and IGR J16479-4514. Together with already known superorbital periodicities in 2S 0114+650 and IGR J16493-4348, the systems exhibit a monotonic relationship between superorbital and orbital periods. These systems include both supergiant fast X-ray transients and classical supergiant systems, and have a range of inclination angles. This suggests an underlying physical mechanism which is connected to the orbital period. In addition to these sources with clear detections of superorbital periods, IGR J16393-4643 (= AX J16390.4-4642) is identified as a system that may have superorbital modulation due to the coincidence of low-amplitude peaks in power spectra derived from BAT, Rossi X-Ray Timing Explorer Proportional Counter Array, and International Gamma-Ray Astrophysics Laboratory light curves. 1E 1145.1-6141 may also be worthy of further attention due to the amount of low-frequency modulation of its light curve. However, we find that the presence of superorbital modulation is not a universal feature of wind-accretion supergiant X-ray binaries.

  3. Infants with complex congenital heart diseases show poor short-term memory in the mobile paradigm at 3 months of age.

    PubMed

    Chen, Chao-Ying; Harrison, Tondi; Heathcock, Jill

    2015-08-01

    The purpose of this study was to examine learning, short-term memory and general development including cognitive, motor, and language domains in infants with Complex Congenital Heart Defects (CCDH). Ten infants with CCHD (4 males, 6 females) and 14 infants with typical development (TD) were examined at 3 months of age. The mobile paradigm, where an infant's leg is tethered to an overhead mobile, was used to evaluate learning and short-term memory. The Bayley Scales of Infant Development 3rd edition (Bayley-III) was used to evaluate general development in cognitive, motor, and language domains. Infants with CCHD and infants with TD both showed learning with significant increase in kicking rate (p<0.001) across periods of the mobile paradigm, but only infants with TD demonstrated short-term memory (p=0.017) in the mobile paradigm. There were no differences on cognitive, motor, and language development between infants with CCHD and infants with TD on the Bayley-III. Early assessment is necessary to guide targeted treatment in infants with CCHD. One-time assessment may fail to detect potential cognitive impairments during early infancy in infants with CCHD. Supportive intervention programs for infants with CCHD that focuses on enhancing short-term memory are recommended.

  4. The Newborn Behavioral Observations (NBO) System as a Form of Intervention and Support for New Parents

    ERIC Educational Resources Information Center

    Nugent, J. Kevin

    2015-01-01

    The period covering the first 3 months of life consists of a series of pivotal, life-changing transitions for the infant, for the parents, and for the emerging parent-child relationship. The Newborn Behavioral Observations (NBO) system is a relationship-based tool that offers individualized information to parents about their baby's communication…

  5. (abstract) Role of Long Equatorial Wave Reflection in the Low-Frequency Variability Observed During the TOPEX/POSEIDON Period: Data Analysis and Coupled Model Study

    NASA Technical Reports Server (NTRS)

    Boulanger, J. P.; Perigaud, C.; Fu, L. L.

    1996-01-01

    The analysis of TOPEX/POSEIDON sea level and ERS-1 zonal wind stress data gives evidence that first mode meridonal long Rossby waves fully reflected into Kelvin waves at the equatorial western Pacific boundary at different periods including the January-June 1994 period. The evolution of the conditions (zonal wind stress, sea surface temperature and sea level anomalies) in the central Pacific suggests that this reflection may have played a role in the reversal of cold to warm anomalies observed in the central Pacific in June-July 1994. To investigate the actual role of reflected Kelvin waves observed by TOPEX/POSEIDON, a simple ocean-atmosphere coupled model is designed. Starting from these initial conditions, several simulations are run for testing the role western bundary reflection evidenced in TOPEX/POSEIDON data. Coupled mechanisms are suggested to explain the low-frequency variability observed during this period.

  6. The histological observations on the large intestine of the goose (Anser anser) during the pre- and post-hatching periods.

    PubMed

    Líman, Narin; Aslan, Sahin; Gülmez, Nurhayat

    2002-08-01

    The development of the cecum and colon in the goose was investigated during the period from the 15th to 28th day of the incubation and from 1 to 30 days of age after hatching by light microscopy. By day 15 of the incubation, in the cecum and colon, the lumen was surrounded by pseudostratified epithelium. The previllous ridges appeared at 15th and 17th days of the incubation in the colon and ceca, respectively. At the base of previllous ridges, the epithelium changed into a simple prismathic epithelium at 15th and 17th days of the incubation in the colon and cecum, respectively. The villi appeared at the 21st days of the incubation. The crypts and goblet cells appeared on the first day after hatching. In the pre-hatching period, the lamina muscularis mucosa was present only in the colon. The submucosa consisted of loosely aggregated connective tissue in the pre-hatching period. In the post-hatching period, it consisted of a very thin layer of connective tissue. Its presence was only obvious where the cells of the submucosal nerve plexus or occasional large blood vessels considerably increased its thickness. The nerve plexus corresponding to the Auerbach's plexus of the mammalian intestine and submucosal nerve plexus appeared by 15th days of the incubation. From the 15th to 28th day of incubation, the tunica muscularis consisted of circular smooth muscle cells in the ceca. On the 28th day of the incubation a thinner longitudinal muscle layer added to the circular muscle layer. In the colon there was an outer longitudinal and a thicker circular muscle layer.

  7. Safety of purified decolorized (low anthraquinone) whole leaf Aloe vera (L) Burm. f. juice in a 3-month drinking water toxicity study in F344 rats.

    PubMed

    Shao, A; Broadmeadow, A; Goddard, G; Bejar, E; Frankos, V

    2013-07-01

    Decolorized (purified, low anthraquinone) whole leaf Aloe vera (L.) Burm. f. juice was administered at concentrations of 0%, 0.5%, 1% and 2% in the drinking water of F344Du rats for 3 months without any adverse effect. The no-observed-adverse-effect level (NOAEL) in this study was considered to be >2%w/v (>1845 mg/kg bodyweight/day for males and >2920 mg/kg bodyweight for females). The test material contained total anthraquinones at <0.1 parts per million. In the present study there was a complete absence of any histological alteration in samples from the cecum, colon (proximal, mid and distal regions). Similar concentrations of non-decolorized (unpurified, high anthraquinone) Aloe vera extracts tested in other studies have resulted in an increased incidence and severity of diarrhea and colon adenomas and carcinomas. The results of this study supports the assertion that the high levels of anthraquinone present in orally administered, non-purified whole leaf Aloe vera extract may be responsible for the adverse effects observed on the colon.

  8. Part 4. Effects of subchronic diesel engine emissions exposure on plasma markers in rodents: report on 1- and 3-month exposures in the ACES bioassay.

    PubMed

    Conklin, Daniel J; Kong, Maiying

    2012-09-01

    Although epidemiologic and experimental studies suggest that exposure to diesel exhaust (DE*) emissions causes adverse cardiovascular effects, neither the specific components of DE nor the mechanisms by which DE exposure could induce cardiovascular dysfunction and exacerbate cardiovascular disease (CVD) are known. Moreover, because the advance of new technologies has resulted in cleaner fuels and decreased engine emissions, there is even more uncertainty about the relationship between DE exposure and cardiovascular health effects. To address this ever-changing baseline of engine emissions, we tested for exposure-, sex- and duration-dependent alterations in plasma markers following subchronic exposure of mice and rats to DE emissions from a 2007-compliant diesel engine. Many plasma markers--several recognized as known human CVD risk factors--were measured in the plasma of rodents exposed to 1 or 3 months of air (the control) or DE emissions. Few changes in plasma markers resulted from exposure to DE, although significant exposure-level-dependent increases in total cholesterol and high-density lipoprotein (HDL) cholesterol were observed in male rats after 1 month of DE exposure, an effect that was neither sustained nor observed in any other group. These data indicate that DE emissions from a 2007-compliant diesel engine as tested in this study had little adverse effect on CVD markers in rodents.

  9. Anomalous domain periodicity observed in ferroelectric PbTiO3 nanodots having 180° stripe domains

    NASA Astrophysics Data System (ADS)

    Son, Jong Yeog; Song, Seungwoo; Lee, Jung-Hoon; Jang, Hyun Myung

    2016-05-01

    Nanometer-scale ferroelectric dots and tubes have received a great deal of attention owing to their potential applications to nonvolatile memories and multi-functional devices. As for the size effect of 180° stripe domains in ferroelectric thin films, there have been numerous reports on the thickness-dependent domain periodicity. All these studies have revealed that the domain periodicity (w) of 180° stripe domains scales with the film thickness (d) according to the classical Landau-Lifshitz-Kittel (LLK) scaling law (w ∝ d1/2) down to the thickness of ~2 nm. In the case of PbTiO3 nanodots, however, we obtained a striking correlation that for the thickness less than a certain critical value, dc (~35 nm), the domain width even increases with decreasing thickness of the nanodot, which surprisingly indicates a negative value in the LLK scaling-law exponent. On the basis of theoretical considerations of dc, we attributed this anomalous domain periodicity to the finite lateral-size effect of a ferroelectric nanodot with an additional effect possibly coming from the existence of a thin non-ferroelectric surface layer.

  10. Anomalous domain periodicity observed in ferroelectric PbTiO3 nanodots having 180° stripe domains

    PubMed Central

    Son, Jong Yeog; Song, Seungwoo; Lee, Jung-Hoon; Jang, Hyun Myung

    2016-01-01

    Nanometer-scale ferroelectric dots and tubes have received a great deal of attention owing to their potential applications to nonvolatile memories and multi-functional devices. As for the size effect of 180° stripe domains in ferroelectric thin films, there have been numerous reports on the thickness-dependent domain periodicity. All these studies have revealed that the domain periodicity (w) of 180° stripe domains scales with the film thickness (d) according to the classical Landau-Lifshitz-Kittel (LLK) scaling law (w ∝ d1/2) down to the thickness of ~2 nm. In the case of PbTiO3 nanodots, however, we obtained a striking correlation that for the thickness less than a certain critical value, dc (~35 nm), the domain width even increases with decreasing thickness of the nanodot, which surprisingly indicates a negative value in the LLK scaling-law exponent. On the basis of theoretical considerations of dc, we attributed this anomalous domain periodicity to the finite lateral-size effect of a ferroelectric nanodot with an additional effect possibly coming from the existence of a thin non-ferroelectric surface layer. PMID:27226162

  11. Auditory evoked arousal responses of 3-month-old infants exposed to methamphetamine in utero: a nap study

    PubMed Central

    Galland, Barbara C; Mitchell, Ed A; Thompson, John MD; Wouldes, Trecia

    2017-01-01

    Aim To investigate whether or not infants exposed to methamphetamine prenatally have impaired arousal responses from sleep. Methods The polygraphic nap studies involved 42 infants aged 3 months exposed to methamphetamine in utero and a comparison group of 57 infants. A proportion of mothers in both groups smoked cigarettes and/or marijuana and drank alcohol during pregnancy. White noise from 50 to 100 decibels (dB) was administered at 10 dB intervals twice within non-rapid eye movement (NREM) and rapid eye movement (REM) sleep states and arousal thresholds measured. Results Combining groups, 306 tests were completed (128 and 178 within REM and NREM sleep, respectively) and infants were more likely to wake at lower thresholds in REM than NREM sleep (hazard ratio 5.58; 95% CI, 3.78–8.23 p < 0.0001). No significant differences in arousal threshold were found between methamphetamine and comparison groups, before or after controlling for other substance use (NREM sleep; 0.98, 95% CI, 0.60–1.59 and REM sleep; 1.03, 95% CI, 0.56–1.89). Conclusions These findings suggest that arousal responses of methamphetamine-exposed infants remain intact, providing no support for the hypothesis that prenatal exposure could increase their vulnerability to sudden infant death syndrome (SIDS) through arousal deficits. PMID:23253105

  12. Excess Body Mass Index Loss at 3 Months: A Predictive Factor of Long-Term Result after Sleeve Gastrectomy

    PubMed Central

    Philouze, Guillaume; Voitellier, Eglantine; Lacaze, Laurence; Huet, Emmanuel; Gancel, Antoine; Prévost, Gaëtan

    2017-01-01

    Introduction. Laparoscopic Sleeve Gastrectomy (SG) is considered as successful if the percentage of Excess Body Mass Index Loss (% EBMIL) remains constant over 50% with long-term follow-up. The aim of this study was to evaluate whether early % EBMIL was predictive of success after SG. Methods. This retrospective study included patients who had SG with two years of follow-up. Patients had follow-up appointments at 3 (M3), 6, 12, and 24 months (M24). Data as weight and Body Mass Index (BMI) were collected systematically. We estimated the % EBMIL necessary to establish a correlation between M3 and M24 compared to % EBMIL speeds and calculated a limit value of % EBMIL predictive of success. Results. Data at operative time, M3, and M24 were available for 128 patients. Pearson test showed a correlation between % EBMIL at M3 and that at M24 (r = 0.74; p < 0.0001). % EBMIL speed between surgery and M3 (p = 0.0011) was significant but not between M3 and M24. A linear regression analysis proved that % EBMIL over 20.1% at M3 (p < 0.0001) predicted a final % EBMIL over 50%. Conclusions. % EBMIL at M3 after SG is correlated with % EBMIL in the long term. % EBMIL speed was significant in the first 3 months. % EBMIL over 20.1% at M3 leads to the success of SG. PMID:28250984

  13. The impact of psychiatric disorders with cardiac syndrome X on quality of life: 3 months prospective study

    PubMed Central

    Altintas, Ebru; Yigit, Fatma; Taskintuna, Nilgun

    2014-01-01

    The aim of the study is to investigate the impact of psychiatric disorders with cardiac syndrome X (CSX) on the patients’ quality of life, as well as the efficacy of psychiatric support. Fifty-six CSX and fifty-three Coronary Heart Disease patients were included in the study after coronary angiography. Patients were evaluated right after the angiography and 3 months thereafter. The socio-demographic characteristics, comorbid disorders, Beck Anxiety (BAI), Depression (BDI) Inventory, and Health Related Quality of Life (SF-36) were compared between groups. The most common mental disorders was depression which account for 41%, the next were anxiety disorders (64%, n = 36) and somatoform (24%, n = 14). Initially, BAI, BDI in the CSX group were significantly higher when compared to the control group. There was significant difference in all subgroups of SF-36 at the end of the second evaluation versus the first evaluation in the CSX patients. The present study revealed that patients with CSX have higher prevalence of psychiatric comorbidities and lower quality of life. Psychiatric approaches are benefit for CSX patients to improvement their quality of life. PMID:25419392

  14. Photometric observations and Numerical modeling of SDSS J162520.29+120308.7, an SU UMa in the CV period gap

    NASA Astrophysics Data System (ADS)

    Montgomery, M. M.; Voloshina, I.; Olenick, Richard; Meziere, Kyle; Metlov, Vladimir

    2017-01-01

    We present R-band photometric observations of Cataclysmic Variable dwarf nova SU UMa SDSS J162520.29+120308.7 during the July 2010 superoutburst, from near maximum through decline and into a single rebrightening. We find a maximum superoutburst amplitude of ∼ 6.1 magnitudes and a maximum rebrightening amplitude of ∼4 magnitudes. Near superoutburst maximum, we find 0.09604(3) days for the mean Stage B positive superhump period and a much longer period for the hump shaped modulation during the rebrightening. For the orbital period, we find Porb = 0.09113(30) days. As all periods both agree and disagree with values reported by others, additional observations are needed. Our 2015 observations of this system in quiescence reveal a 0.09080(20) day orbital period. As our 2010 value is within the error bars of a spectroscopically determined value and our 2015 photometrically determined value, we suggest 0.09113(30) days as the orbital period for this system. As for the secondary-to-primary mass ratio, analytical models using observed orbital and Stage B positive superhump periods as input suggest q = 0.221. As a check, we present a 3D SPH simulation of the rise to, and during the plateau stage of, the SU UMa in superoutburst, assuming Porb=0.09113 days. For Stages A and B, we find 0.09717 days and 0.09702 days, respectively, for the average simulated positive superhump periods. Analytical models using these simulated Stages A and B and the simulated orbital period suggest q = 0.1920(4) and q = 0.221, respectively, for this system. Due to the poorly constrained observational data and the similar mass ratio estimates regardless of stage, we can neither confirm nor deny that Stage A is better than Stage B for determining mass ratio in CV dwarf novae SU UMa systems. Additional observations and simulations are needed to further test this recently proposed hypothesis. For now, we suggest an average q = 0.21(1) for this system.

  15. Observations and Modeling of Low Level Moisture Convergence Patterns in the Southern Appalachians during the Integrated Precipitation and Hydrology Experiment (IPHEx) Extended Observing Period

    NASA Astrophysics Data System (ADS)

    Wilson, Anna M.; Barros, Ana P.

    2015-04-01

    Accurate fields of precipitation accumulations and intensity at high spatial resolution in regions of complex terrain are largely unavailable. This is due to first, a lack of existing in situ observations, both because of the challenge in having high enough density in the instrument placement to represent the large spatial heterogeneity in rainfall patterns in these regions and because of the remote, harsh nature of the terrain that makes it difficult to install and maintain instrumentation and second, obstacles to remote sensing such as beam blockage and ground clutter that are caused by the complex orography. In this study we leverage observations from two sources: 1) a high-elevation, high-density tipping bucket rain gauge network that has been recording precipitation observations for over six years along ridgelines in the Pigeon River Basin, a small watershed in the Southern Appalachians, and 2) the 4-D database of observations collected in 2014 in support of the Global Precipitation Mission (GPM) during the first field campaign after the launch of the GPM satellite, the Integrated Precipitation and Hydrology Experiment (IPHEx), to learn about formation and maintenance mechanisms for fog and low cloud in this region and the resulting impact on the precipitation regime. The observations focused on here are those at the near surface, within 2 kilometers of the ground level. This presentation will focus on process-based modeling studies using the Advanced Research Weather and Forecasting Model conducted based upon observations made during this campaign. Case studies will be presented for real events simulated during the IPHEx campaign. These case studies occurred with different synoptic conditions, but include observational evidence of orographic enhancement. The case studies are simulated and analyzed in order to investigate how the topography modulates the regional, diurnal patterns of moisture convergence and fog and low cloud formation, as well as the mid

  16. Observations of the surge-type Black Rapids Glacier, Alaska, during a quiescent period, 1970-92

    USGS Publications Warehouse

    Heinrichs, Thomas A.; Mayo, L.R.; Trabant, D.C.; March, R.S.

    1995-01-01

    This report presents 23 years (1970 to 1992) of observations of Black Rapids Glacier, Alaska. Black Rapids Glacier is a surge-type glacier which most recently surged in 1936-37, and is currently in its quiescent phase. This glacier is of special interest because it is a potential hazard to the trans-Alaska oil pipeline. Ten sites on the glacier were monitored from 1972 to 1987, and three sites were monitored from 1988 to 1992. The measurement program presented here includes observations of surface mass balance, ice velocity, and surface altitude made twice each year. Additional one-time data include observations of ice thickness, previously unreported observations of the 1936-37 surge, establishment of the geodetic control monuments, and a new map of Black Rapids Glacier.

  17. Using dissolved gases to observe the evolution of groundwater age in a mountain watershed over a period of thirteen years

    USGS Publications Warehouse

    Manning, Andrew H.

    2011-01-01

    Baseflows in snowmelt-dominated mountain streams are critical for sustaining ecosystems and water resources during periods of greatest demand. Future climate predictions for mountainous areas throughout much of the western U.S. include increasing temperatures, declining snowpacks, and earlier snowmelt periods. The degree to and rate at which these changes will affect baseflows in mountain streams remains unknown, largely because baseflows are groundwater-fed and the relationship between climate and groundwater recharge/discharge rates in mountain watersheds is uncertain. We use groundwater age determinations from multiple dissolved gas tracers (CFCs, SF6, and 3H/3He) to track changes in groundwater age over a period of thirteen years in the Sagehen Creek watershed, Sierra Nevada Mountains, CA. Data were collected from springs and wells in 2009 and 2010 and combined with those obtained in prior studies from 1997 to 2003. Apparent ages range from 0 to >60 years. Comparison between variations in age and variations in snow water equivalent (SWE) and mean annual air temperature reveals the degree of correlation between these climate variables and recharge rate. Further, comparison of apparent ages from individual springs obtained at different times and using different tracers helps constrain the age distribution in the sampled waters. The age data are generally more consistent with an exponential age distribution than with piston-flow. However, many samples, even those with relatively old mean ages, must have a disproportionately large very young fraction that responds directly to annual SWE variations. These findings have important implications for how future baseflows may respond to decreasing SWE.

  18. Multi-Wavelength Observations On The Gamma-Ray Blazar PG1553+113 As A Probe For Geometrical Periodical Modulation

    NASA Astrophysics Data System (ADS)

    Stamerra, Antonio; Prandini, E.; Paiano, S.; Da Vela, P.; Gareth, H.; Covino, S.; Cutini, S.; Sandrinelli, A.; Sobacchi, E.; Sormani, M. C.

    2016-10-01

    New claims of periodic variability from gamma-ray blazars have been reported, possibly pointing at milli-pc SMBH binary systems. A modulation of 2 year on 3.5 cycles was recently discovered with Fermi/LAT on the blazar PG1553+113 - for the first time in gamma-rays with high significance - and confirmed by optical lightcurves. Other possible gamma-ray periodic variations have been claimed on PKS 2155-304 and PKS 0537 by Sandrinelli et al. (2015, 2016). The interpretation of such periodicity, when confirmed with continuous observations in following years, is not straightforward. Emission from blazars is dominated by non-thermal emission from the jet; different processes in the jet or at its base, may lead to quasi-periodic emission. We used multi-wavelength (MWL) observations on PG1553+113 to investigate if the observed modulation can be explained with geometrical variations in the jet, possibly pointing to jet precession or to an helical pattern. The ongoing MWL monitoring campaign from radio to very-high energy gamma-ray bands, led by the MAGIC collaboration, will follow the maximum expected at the beginning of 2017, and will allow to set tighter constrains on underlying periodic processes.

  19. Factors Affecting Health Insurance Enrollment Through the State Marketplaces: Observations on the ACA's Third Open Enrollment Period.

    PubMed

    Giovannelli, Justin; Curran, Emily

    2016-07-01

    Issue: Nearly 12.7 million individuals signed up for coverage in the Affordable Care Act's (ACA) health insurance marketplaces during the third open enrollment period, and by the end of March there were 11.1 million consumers with active coverage. States that operate their own marketplaces posted a year-to-year enrollment gain of 8.8 percent. To maintain membership and attract new consumers, the state-based marketplaces must sponsor enrollment assistance programs and conduct consumer outreach. These marketplaces relied heavily on such efforts during the third enrollment period, despite declining funding. Goal: To learn which outreach strategies, assistance programs, and other factors marketplace officials viewed as having exerted the greatest influence on enrollment. Methods: Survey of officials representing each of the 17 state-based marketplaces (15 responses). Key findings and conclusions: The cost of coverage and low health insurance literacy pose significant barriers to enrollment for many consumers. Marketplaces sought to overcome them by encouraging consumers to obtain in-person enrollment assistance from ACA-created assistance programs and from insurance brokers, and by partnering with community organizations for outreach activities. Many marketplaces also enhanced their web portals to make them easier to navigate and to give consumers better tools with which to evaluate their coverage options.

  20. Observation

    ERIC Educational Resources Information Center

    Helfrich, Shannon

    2016-01-01

    Helfrich addresses two perspectives from which to think about observation in the classroom: that of the teacher observing her classroom, her group, and its needs, and that of the outside observer coming into the classroom. Offering advice from her own experience, she encourages and defends both. Do not be afraid of the disruption of outside…

  1. Observations

    ERIC Educational Resources Information Center

    Joosten, Albert Max

    2016-01-01

    Joosten begins his article by telling us that love and knowledge together are the foundation for our work with children. This combination is at the heart of our observation. With this as the foundation, he goes on to offer practical advice to aid our practice of observation. He offers a "List of Objects of Observation" to help guide our…

  2. Inner magnetosphere variations after solar proton events. Observations on Mir space station in 1989-1994 time period.

    PubMed

    Dachev TsP; Semkova, J V; Matviichuk YuN; Tomov, B T; Koleva, R T; Baynov, P T; Petrov, V M; Shurshakov, V V; Ivanov, Y u

    1998-01-01

    Measurements on board the Mir space station have been used to study the dose rate and the particle flux distribution in the inner magnetosphere. The measurements have been performed with the Bulgarian-Russian dosimeter-radiometer Liulin. The paper concentrates on the dynamics of the observed "new" and "second" maxima which were created after Solar Proton Events (SPE) in the 1989-1994 time. The "second" belt was first observed after the SPE on October 20, 1989, and the last observation was after the SPE on February 20, 1994. The creation of the "new" belt is a unique phenomena seen in the Liulin data set after the SPE on March 23, 1991 and relates to the magnetic storm on March 24. The new belt fully disappears in the middle of 1993.

  3. Experimental observations on the response of 1(st) and 2(nd) order fibre optic long period grating coupling bands to the deposition of nanostructured coatings.

    PubMed

    James, Stephen W; Cheung, C S; Tatam, Ralph P

    2007-10-01

    The sensitivity of attenuation bands corresponding to the 2(nd) order coupling to cladding modes by a fibre optic long period grating (LPG) to the deposition of nanostructured coatings is investigated and compared with that of the 1(st) order coupling. The experimental observations support previously reported theoretical descriptions of LPGs with nanoscale coatings.

  4. Efficacy and Safety of Paliperidone Palmitate 3-Month Formulation for Patients with Schizophrenia: A Randomized, Multicenter, Double-Blind, Noninferiority Study

    PubMed Central

    Xu, Haiyan; Gopal, Srihari; Nuamah, Isaac; Ravenstijn, Paulien; Janik, Adam; Schotte, Alain; Hough, David; Fleischhacker, Wolfgang W.

    2016-01-01

    Background: This double-blind, parallel-group, multicenter, phase-3 study was designed to test the noninferiority of paliperidone palmitate 3-month formulation (PP3M) to the currently marketed 1-month formulation (PP1M) in patients (age 18–70 years) with schizophrenia, previously stabilized on PP1M. Methods: After screening (≤3 weeks) and a 17-week, flexible-dosed, open-label phase (PP1M: day 1 [150mg eq. deltoid], day 8 [100mg eq. deltoid.], weeks 5, 9, and 13 [50, 75, 100, or 150mg eq., deltoid/gluteal]), clinically stable patients were randomized (1:1) to PP3M (fixed-dose, 175, 263, 350, or 525mg eq. deltoid/gluteal) or PP1M (fixed-dose, 50, 75, 100, or 150mg eq. deltoid/gluteal) for a 48-week double-blind phase. Results: Overall, 1016/1429 open-label patients entered the double-blind phase (PP3M: n=504; PP1M: n=512) and 842 completed it (including patients with relapse). PP3M was noninferior to PP1M: relapse rates were similar in both groups (PP3M: n=37, 8%; PP1M: n=45, 9%; difference in relapse-free rate: 1.2% [95% CI:-2.7%; 5.1%]) based on Kaplan-Meier estimates (primary efficacy). Secondary endpoint results (changes from double-blind baseline in positive and negative symptom score total and subscale scores, Clinical Global Impression-Severity, and Personal and Social Performance scores) were consistent with primary endpoint results. No clinically relevant differences were observed in pharmacokinetic exposures between PP3M and PP1M. Both groups had similar tolerability profiles; increased weight was the most common treatment-emergent adverse event (double-blind phase; 21% each). No new safety signals were detected. Conclusion: Taken together, PP3M with its 3-month dosing interval is a unique option for relapse prevention in schizophrenia. PMID:26902950

  5. Observation of electron states of small period artificial graphene in nano-patterned GaAs quantum wells

    NASA Astrophysics Data System (ADS)

    Wang, Sheng; Scarabelli, Diego; Kuznetsova, Yuliya Y.; Wind, Shalom J.; Pinczuk, Aron; Pellegrini, Vittorio; Manfra, Michael J.; Gardner, Geoff C.; Pfeiffer, Loren N.; West, Ken W.

    2016-09-01

    Engineered honeycomb lattices, called artificial graphene (AG), are tunable platforms for the study of novel electronic states related to Dirac physics. In this work, we report the achievement of electronic bands of the honeycomb topology with the period as low as 40 nm on the nano-patterned modulation-doped AlGaAs/GaAs quantum wells. Resonant inelastic light scattering spectra reveal peaks which are interpreted as combined electronic transitions between subbands of the quantum well confinement with a change in the AG band index. Spectra lineshapes are explained by joint density of states obtained from the calculated AG electron band structures. These results provide a basis for further advancements in AG physics.

  6. A 3-Month Jump-Landing Training Program: A Feasibility Study Using the RE-AIM Framework

    PubMed Central

    Aerts, Inne; Cumps, Elke; Verhagen, Evert; Mathieu, Niels; Van Schuerbeeck, Sander; Meeusen, Romain

    2013-01-01

    Context: Evaluating the translatability and feasibility of an intervention program has become as important as determining the effectiveness of the intervention. Objective: To evaluate the applicability of a 3-month jump-landing training program in basketball players, using the RE-AIM (reach, effectiveness, adoption, implementation, and maintenance) framework. Design: Randomized controlled trial. Setting: National and regional basketball teams. Patients or Other Participants: Twenty-four teams of the second highest national division and regional basketball divisions in Flanders, Belgium, were randomly assigned (1:1) to a control group and intervention group. A total of 243 athletes (control group = 129, intervention group = 114), ages 15 to 41 years, volunteered. Intervention(s): All exercises in the intervention program followed a progressive development, emphasizing lower extremity alignment during jump-landing activities. Main Outcome Measure(s): The results of the process evaluation of the intervention program were based on the 5 dimensions of the RE-AIM framework. The injury incidence density, hazard ratios, and 95% confidence intervals were determined. Results: The participation rate of the total sample was 100% (reach). The hazard ratio was different between the intervention group and the control group (0.40 [95% confidence interval = 0.16, 0.99]; effectiveness). Of the 12 teams in the intervention group, 8 teams (66.7%) agreed to participate in the study (adoption). Eight of the participating coaches (66.7%) felt positively about the intervention program and stated that they had implemented the training sessions of the program as intended (implementation). All coaches except 1 (87.5%) intended to continue the intervention program the next season (maintenance). Conclusions: Compliance of the coaches in this coach-supervised jump-landing training program was high. In addition, the program was effective in preventing lower extremity injuries. PMID:23675788

  7. Infant Temperament and Parent Stress in 3 month old Infants following Surgery for Complex Congenital Heart Disease

    PubMed Central

    Torowicz, Deborah; Irving, Sharon Y; Hanlon, Alexandra L.; Sumpter, Danica Fulbright; Medoff-Cooper, Barbara

    2010-01-01

    Objective This study aimed to identify and compare differences in temperament and maternal stress between infants with complex congenital heart disease (CHD) and healthy controls at 3 months of age. Methods Study sample was drawn from an existing longitudinal study examining growth in infants with CHD as compared to healthy controls. Infant temperament and parental stress were measured in 129 mother-infant dyads. Inclusion criteria for infants with CHD were ≥ 36 weeks post-menstrual age, ≥ 2500 grams at birth, surgery in first 6 weeks of life, and no major congenital anomalies or genetic syndromes. The Early Infancy Temperament Questionnaire and Parent Stress Index were the assessment tools used. Results Infants with single ventricle (SV) physiology were more negative in mood (F=7.14, p<0.001) and less distractible (F=5.00, p<0.008) than the biventricular physiology (BV) or control (C) infant groups. The demands of care for infants with CHD was a source of stress as compared to control infants (p<.05). Five of six subscales of the Child Domain were significant sources of stress in the SV group compared to BV and Control groups. Negative mood and difficulty to soothe were predictors for Child Domain and Total Life Stress in SV infants. Conclusion The demands of parenting an irritable infant with SV physiology puts these mothers at risk for high levels of stress. Results suggest the need for pre-discharge anticipatory guidance for parents to better understand and respond to the behavioral style of their infants, in particular, infants with SV physiology. PMID:20375737

  8. Mother-preterm infant interactions at 3 months of corrected age: influence of maternal depression, anxiety and neonatal birth weight

    PubMed Central

    Neri, Erica; Agostini, Francesca; Salvatori, Paola; Biasini, Augusto; Monti, Fiorella

    2015-01-01

    Maternal depression and anxiety represent risk factors for the quality of early mother-preterm infant interactions, especially in the case of preterm birth. Despite the presence of many studies on this topic, the comorbidity of depressive and anxious symptoms has not been sufficiently investigated, as well as their relationship with the severity of prematurity and the quality of early interactions. The Aim of this study was to evaluate the quality of early mother-infant interactions and the prevalence of maternal depression and anxiety comparing dyads of extremely low birth weight (ELBW) and very low birth weight (VLBW) preterm infants with full-term ones. Seventy seven preterm infants (32 ELBW; 45 VLBW) and 120 full term (FT) infants and their mothers were recruited. At 3 months of corrected age, 5 min of mother-infant interactions were recorded and later coded through the Global Ratings Scales. Mothers completed the Edinburgh Postnatal Depression Scale and Penn State Worry Questionnaire. Infant levels of development were assessed through the Griffiths Mental Development Scales. A relation emerged among the severity of prematurity, depression, anxiety, and the quality of interactions. When compared with the FT group, the ELBW interactions were characterized by high maternal intrusiveness and low remoteness, while the VLBW dyads showed high levels of maternal sensitivity and infant communication. Depression was related to maternal remoteness and negative affective state, anxiety to low sensitivity, while infant interactive behaviors were impaired only in case of comorbidity. ELBW’s mothers showed the highest prevalence of depressive and anxious symptoms; moreover, only in FT dyads, low maternal sensitivity, negative affective state and minor infant communication were associated to the presence of anxious symptoms. The results confirmed the impact of prematurity on mother–infant interactions and on maternal affective state. Early diagnosis can help to plan

  9. How a hat may affect 3-month-olds' recognition of a face: an eye-tracking study.

    PubMed

    Bulf, Hermann; Valenza, Eloisa; Turati, Chiara

    2013-01-01

    Recent studies have shown that infants' face recognition rests on a robust face representation that is resilient to a variety of facial transformations such as rotations in depth, motion, occlusion or deprivation of inner/outer features. Here, we investigated whether 3-month-old infants' ability to represent the invariant aspects of a face is affected by the presence of an external add-on element, i.e. a hat. Using a visual habituation task, three experiments were carried out in which face recognition was investigated by manipulating the presence/absence of a hat during face encoding (i.e. habituation phase) and face recognition (i.e. test phase). An eye-tracker system was used to record the time infants spent looking at face-relevant information compared to the hat. The results showed that infants' face recognition was not affected by the presence of the external element when the type of the hat did not vary between the habituation and test phases, and when both the novel and the familiar face wore the same hat during the test phase (Experiment 1). Infants' ability to recognize the invariant aspects of a face was preserved also when the hat was absent in the habituation phase and the same hat was shown only during the test phase (Experiment 2). Conversely, when the novel face identity competed with a novel hat, the hat triggered the infants' attention, interfering with the recognition process and preventing the infants' preference for the novel face during the test phase (Experiment 3). Findings from the current study shed light on how faces and objects are processed when they are simultaneously presented in the same visual scene, contributing to an understanding of how infants respond to the multiple and composite information available in their surrounding environment.

  10. Oxalosis in primary hyperoxaluria in infancy : Report of a case in a 3-month-old baby. Follow-up for 3 years and review of literature.

    PubMed

    Orazi, Cinzia; Picca, Stefano; Schingo, Paolo M S; Fassari, Fausto M; Canepa, Giuseppe

    2009-04-01

    Primary hyperoxaluria (PH1) is a rare inborn autosomal recessive metabolic disorder due to the deficiency of hepatic alanine-glyoxylate-aminotransferase. This deficiency results in excessive synthesis and urinary excretion of oxalate, inducing renal stone formation and deposition of calcium oxalate in the kidney, bone, myocardium, and vessels (systemic oxalosis, SO) in the most severely affected individuals. We report renal and skeletal changes in a 3-month-old girl with PH1 and SO. Intense cortico-medullary hyperechogenicity and increased homogeneous radiopacity of normal-sized kidneys suggested the diagnosis of SO. Skeletal survey showed osteopenia and characteristic symmetrical metaphyseal transverse bands in long bones, progressively becoming more dense and migrating towards the diaphysis. Multiple pathological and slowly healing fractures of the limbs occurred at the dense band level. A radiopaque rim was then observed in flat bones, epiphyseal nuclei, and vertebral bodies. Inflammatory granulomatous reaction, induced by the presence of oxalate crystals in the marrow spaces, coexisted with progressively evident radiological signs of secondary hyperparathyroidism, with partially overlapping features. The patient was treated by peritoneal dialysis and hemodialysis until combined liver-kidney transplantation. There are no previous reports of infants treated with hemodialysis for more than 2 years.

  11. Observation of quasi-periodic frequency sweeping in electron cyclotron emission of nonequilibrium mirror-confined plasma

    NASA Astrophysics Data System (ADS)

    Viktorov, M. E.; Shalashov, A. G.; Mansfeld, D. A.; Golubev, S. V.

    2016-12-01

    Chirping frequency patterns have been observed in the electron cyclotron emission from strongly nonequilibrium plasma confined in a table-top mirror magnetic trap. Such patterns are typical for the formation of nonlinear phase-space structures in a proximity of the wave-particle resonances of a kinetically unstable plasma, also known as the “holes and clumps” mechanism. Our data provides the first experimental evidence for the acting of this mechanism in the electron cyclotron frequency domain.

  12. Satellite observations of atmospheric SO 2 from volcanic eruptions during the time-period of 1996-2002

    NASA Astrophysics Data System (ADS)

    Khokhar, M. F.; Frankenberg, C.; Van Roozendael, M.; Beirle, S.; Kühl, S.; Richter, A.; Platt, U.; Wagner, T.

    In this article, we present satellite observations of atmospheric sulfur dioxide (SO 2) from volcanic eruptions. Global ozone monitoring experiment (GOME) data for the years 1996-2002 is analyzed using a DOAS based algorithm with the aim of retrieving SO 2 slant column densities (SCD). The retrieval of SO 2 SCD in the UV spectral region is difficult due to strong and interfering ozone absorptions. It is also likely affected by instrumental effects. We investigated these effects in detail to obviate systematic biases in the SO 2 retrieval. A quantitative study of about 20 volcanoes from Italy, Iceland, Congo/Zaire, Ecuador, Japan, Vanuatu Island and Mexico is presented. The focus is on both eruption and out gassing scenarios. We prepared a 7-year mean map (1996-2002) of SO 2 SCD observed by GOME and tabulated the ratios of the maximum SO 2 SCD observed to the average SO 2 SCD as seen in the 7-year mean map. The further aim of this study is to provide information about unknown volcanic eruptions, e.g., Bandai Honshu Japan, Central Islands Vanuatu, Piton de la Fournaise Réunion Island France, Kamchatka region of Russia and from Indonesia especially. The results demonstrate a high sensitivity of the GOME instrument towards SO 2 emissions during both eruption and degassing episodes.

  13. Wave structures observed in the equatorial F-region plasma density and temperature during the sunset period

    NASA Astrophysics Data System (ADS)

    Savio, S.; Muralikrishna, P.; Batista, I. S.; de Meneses, F. C.

    2016-11-01

    Electron density and temperature measurements were carried out with Langmuir probes (LP) on board Brazilian sounding rockets launched soon after the local sunset from Natal (5.8°S, 35.2°W, dip 23.7°S) and Alcântara (2.3°S, 44.4°W, dip 7°S), Brazil, on December 02, 2011, and December 08, 2012, respectively. Digisondes operating near the launching sites revealed a rapid rise in the F-region base indicating a probable pre-reversal enhancement of the vertical plasma drift. Strong spread-F traces are also visible on the ionograms simultaneously recorded, suggesting the occurrence of ionospheric bubbles during these campaigns. Electron density and temperature vertical profiles estimated from the LP data exhibit in the E-F region valley (120-300 km) the presence of large-amplitude wave activity, and electron temperature values higher than 1600 K, respectively, phenomena probably related to the electrodynamic processes that occur during the sunset period.

  14. Ground-based Solar Observations and Plasma Bubbles in Brazilian Sector During a Period of Extreme Low Solar Activity

    NASA Astrophysics Data System (ADS)

    Tardelli-Coelho, F.; Abalde, J. R.; Tardelli, A.; de Abreu, A. J.

    2016-04-01

    Studies presented on the relation of the Sun-Earth system are currently of great importance. Ionospheric irregularities in the F-region, caused by geomagnetic storms have significant and adverse effects on the Earth. The recent advancement in technological techniques for monitoring space weather has facilitated these studies. The focus of this study was to determine whether a geomagnetic storm interfered with the generation, propagation, and durability of plasma bubbles that occurred over a period of solar minimum in two cities in the Brazilian sector, São José dos Campos - SP, designated SJC, (23.21°S, 45.86°W; dip latitude 17.6°S), low-latitude region and near the south crest of the ionospheric equatorial anomaly; and Palmas - TO, called PAL (10.28°S, 48.33°W; dip latitude 6.7°S), near the magnetic equator, located in the geographical South, tropical region and the hemisphere opposite the magnetic equator. This study was conducted with data analysis of five years (2006-2010) for SJC and four years (2007-2010) for PAL, considering the 24th solar cycle, using an all-sky imaging photometer operating with interference filters in OI 630.0 nm emission resulting from dissociative recombination process that occurs at an altitude of 250-300 km (F-region).

  15. Observation

    ERIC Educational Resources Information Center

    Kripalani, Lakshmi A.

    2016-01-01

    The adult who is inexperienced in the art of observation may, even with the best intentions, react to a child's behavior in a way that hinders instead of helping the child's development. Kripalani outlines the need for training and practice in observation in order to "understand the needs of the children and...to understand how to remove…

  16. Earth Observing-1 Advanced Imager Flight Performance Assessment: Investigating Dark Current Stability Over One-Half Orbit Period during the First 60 Days

    NASA Technical Reports Server (NTRS)

    Mendenhall, J. A.

    2001-01-01

    The stability of the EO-1 Advanced Land Imager dark current levels over the period of one-half orbit is investigated. A series of two-second dark current collections, over the course of 40 minutes, was performed during the first sixty days the instrument was in orbit. Analysis of this data indicates only two dark current reference periods, obtained entering and exiting eclipse, are required to remove ALI dark current offsets for 99.9% of the focal plane to within 1.5 digital numbers for any observation on the solar illuminated portion of the orbit.

  17. A statistical analysis of energy and power demand for the tractive purposes of an electric vehicle in urban traffic - an analysis of a short and long observation period

    NASA Astrophysics Data System (ADS)

    Slaski, G.; Ohde, B.

    2016-09-01

    The article presents the results of a statistical dispersion analysis of an energy and power demand for tractive purposes of a battery electric vehicle. The authors compare data distribution for different values of an average speed in two approaches, namely a short and long period of observation. The short period of observation (generally around several hundred meters) results from a previously proposed macroscopic energy consumption model based on an average speed per road section. This approach yielded high values of standard deviation and coefficient of variation (the ratio between standard deviation and the mean) around 0.7-1.2. The long period of observation (about several kilometers long) is similar in length to standardized speed cycles used in testing a vehicle energy consumption and available range. The data were analysed to determine the impact of observation length on the energy and power demand variation. The analysis was based on a simulation of electric power and energy consumption performed with speed profiles data recorded in Poznan agglomeration.

  18. Observations and modeling of the companions of short period binary millisecond pulsars: evidence for high-mass neutron stars

    SciTech Connect

    Schroeder, Joshua; Halpern, Jules

    2014-10-01

    We present observations of fields containing eight recently discovered binary millisecond pulsars using the telescopes at MDM Observatory. Optical counterparts to four of these systems are detected, one of which, PSR J2214+3000, is a novel detection. Additionally, we present the fully phase-resolved B, V, and R light curves of the optical counterparts to two objects, PSR J1810+1744 and PSR J2215+5135 for which we employ model fitting using the eclipsing light curve (ELC) model of Orosz and Hauschildt to measure the unknown system parameters. For PSR J1810+1744, we find that the system parameters cannot be fit even assuming that 100% of the spin-down luminosity of the pulsar is irradiating the secondary, and so radial velocity measurements of this object will be required for the complete solution. However, PSR J2215+5135 exhibits light curves that are extremely well constrained using the ELC model and we find that the mass of the neutron star is constrained by these and the radio observations to be M {sub NS} > 1.75 M {sub ☉} at the 3σ level. We also find a discrepancy between the model temperature and the measured colors of this object, which we interpret as possible evidence for an additional high-temperature source such as a quiescent disk. Given this and the fact that PSR J2215+5135 contains a relatively high mass companion (M {sub c} > 0.1 M {sub ☉}), we propose that similar to the binary pulsar systems PSR J1023+0038 and IGR J18245–2452, the pulsar may transition between accretion- and rotation-powered modes.

  19. Observations and Modeling of the Companions of Short Period Binary Millisecond Pulsars: Evidence for High-mass Neutron Stars

    NASA Astrophysics Data System (ADS)

    Schroeder, Joshua; Halpern, Jules

    2014-10-01

    We present observations of fields containing eight recently discovered binary millisecond pulsars using the telescopes at MDM Observatory. Optical counterparts to four of these systems are detected, one of which, PSR J2214+3000, is a novel detection. Additionally, we present the fully phase-resolved B, V, and R light curves of the optical counterparts to two objects, PSR J1810+1744 and PSR J2215+5135 for which we employ model fitting using the eclipsing light curve (ELC) model of Orosz & Hauschildt to measure the unknown system parameters. For PSR J1810+1744, we find that the system parameters cannot be fit even assuming that 100% of the spin-down luminosity of the pulsar is irradiating the secondary, and so radial velocity measurements of this object will be required for the complete solution. However, PSR J2215+5135 exhibits light curves that are extremely well constrained using the ELC model and we find that the mass of the neutron star is constrained by these and the radio observations to be M NS > 1.75 M ⊙ at the 3σ level. We also find a discrepancy between the model temperature and the measured colors of this object, which we interpret as possible evidence for an additional high-temperature source such as a quiescent disk. Given this and the fact that PSR J2215+5135 contains a relatively high mass companion (M c > 0.1 M ⊙), we propose that similar to the binary pulsar systems PSR J1023+0038 and IGR J18245-2452, the pulsar may transition between accretion- and rotation-powered modes.

  20. Long-period oscillations of sunspot magnetic fields by simultaneous observations of the Global Oscillation Network Group and Solar and Heliospheric Observatory/Michelson Doppler imager

    NASA Astrophysics Data System (ADS)

    Efremov, V. I.; Parfinenko, L. D.; Solov'ev, A. A.; Riehokainen, A.

    2016-12-01

    For the first time, the ultra-low oscillation mode of the sunspot magnetic field strength has been detected with a high degree of confidence by ground-based observations of sunspots with the Global Oscillation Network Group (GONG) network of telescopes. Synchronous series of magnetograms derived from the GONG and Solar and Heliospheric Observatory/Michelson Doppler Imager (SOHO/MDI) have been processed. They were obtained on September 27-30, 2010, for the active region NOAA 11109 with a total duration of 80 h. The periods of magnetic field oscillations found by space data coincide with the periods defined with GONG. This confirms the physical reality of the oscillatory process. The power spectrum contains harmonics with periods of 26 h, 8-10 h, and 3-4 h.

  1. Influence of regional biomass burning on the highly elevated organic carbon concentrations observed at Gosan, South Korea during a strong Asian dust period.

    PubMed

    Nguyen, Duc Luong; Kim, Jin Young; Ghim, Young Sung; Shim, Shang-Gyoo

    2015-03-01

    PM2.5 carbonaceous particles were measured at Gosan, South Korea during 29 March-11 April 2002 which includes a pollution period (30 March-01 April) when the highest concentrations of major anthropogenic species (nss-SO4 (2-), NO3 (-), and NH4 (+)) were observed and a strong Asian dust (AD) period (08-10 April) when the highest concentrations of mainly dust-originated trace elements (Al, Ca, Mg, and Fe) were seen. The concentrations of elemental carbon (EC) measured in the pollution period were higher than those measured in the strong AD period, whereas an inverse variation in the concentrations of organic carbon (OC) was observed. Based on the OC/EC ratios, the possible source that mainly contributed to the highly elevated OC concentrations measured in the strong AD period was biomass burning. The influence of the long-range transport of smoke plumes emitted from regional biomass burning sources was evaluated by using MODIS (Moderate Resolution Imaging Spectroradiometer) satellite data for fire locations and the potential source contribution function analysis. The most potential source regions of biomass burning were the Primorsky and Amur regions in Far Eastern Russia and southeastern and southwestern Siberia, Russia. Further discussion on the source characteristics suggested that the high OC concentrations measured in the strong AD period were significantly affected by the smoldering phase of biomass burning. In addition to biomass burning, secondary OC (SOC) formed during atmospheric long-range transport should be also considered as an important source of OC concentration measured at Gosan. Although this study dealt with the episodic case of the concurrent increase of dust and biomass burning particles, understanding the characteristics of heterogeneous mixing aerosol is essential in assessing the radiative forcing of aerosol.

  2. Long-period effects of the Denali earthquake on water bodies in the Puget Lowland: Observations and modeling

    USGS Publications Warehouse

    Barberopoulou, A.; Qamar, A.; Pratt, T.L.; Steele, W.P.

    2006-01-01

    Analysis of strong-motion instrument recordings in Seattle, Washington, resulting from the 2002 Mw 7.9 Denali, Alaska, earthquake reveals that amplification in the 0.2-to 1.0-Hz frequency band is largely governed by the shallow sediments both inside and outside the sedimentary basins beneath the Puget Lowland. Sites above the deep sedimentary strata show additional seismic-wave amplification in the 0.04- to 0.2-Hz frequency range. Surface waves generated by the Mw 7.9 Denali, Alaska, earthquake of 3 November 2002 produced pronounced water waves across Washington state. The largest water waves coincided with the area of largest seismic-wave amplification underlain by the Seattle basin. In the current work, we present reports that show Lakes Union and Washington, both located on the Seattle basin, are susceptible to large water waves generated by large local earthquakes and teleseisms. A simple model of a water body is adopted to explain the generation of waves in water basins. This model provides reasonable estimates for the water-wave amplitudes in swimming pools during the Denali earthquake but appears to underestimate the waves observed in Lake Union.

  3. Observation of Periodic and Transient Cosmic Ray Flux Variations by the Daejeon Neutron Monitor and the Seoul muon Detector

    NASA Astrophysics Data System (ADS)

    Oh, Suyeon; Kang, Jeongsoo

    2013-09-01

    Recently, two instruments of cosmic ray are operating in South Korea. One is Seoul muon detector after October 1999 and the other is Daejeon neutron monitor (Kang et al. 2012) after October 2011. The former consists of four small plastic scintillators and the latter is the standard 18 NM 64 type. In this report, we introduce the characteristics of both instruments. We also analyze the flux variations of cosmic ray such as diurnal variation and Forbush decrease. As the result, the muon flux shows the typical seasonal and diurnal variations. The neutron flux also shows the diurnal variation. The phase which shows the maximum flux in the diurnal variation is around 13-14 local time. We found a Forbush decrease on 7 March 2012 by both instruments. It is also identified by Nagoya multi-direction muon telescope and Oulu neutron monitor. The observation of cosmic ray at Jangbogo station as well as in Korean peninsula can support the important information on space weather in local area. It can also enhance the status of Korea in the international community of cosmic ray experiments.

  4. Quasi-periodic variations in x-ray emission and long-term radio observations: Evidence for a two-component jet in Sw J1644+57

    SciTech Connect

    Wang, Jiu-Zhou; Lei, Wei-Hua; Wang, Ding-Xiong; Zou, Yuan-Chuan; Huang, Chang-Yin; Zhang, Bing; Gao, He E-mail: dxwang@hust.edu.cn E-mail: zhang@physics.unlv.edu

    2014-06-10

    The continued observations of Sw J1644+57 in X-ray and radio bands accumulated a rich data set to study the relativistic jet launched in this tidal disruption event. The X-ray light curve of Sw J1644+57 from 5-30 days presents two kinds of quasi-periodic variations: a 200 s quasi-periodic oscillation (QPO) and a 2.7 day quasi-periodic variation. The latter has been interpreted by a precessing jet launched near the Bardeen-Petterson radius of a warped disk. Here we suggest that the ∼200 s QPO could be associated with a second, narrower jet sweeping the observer line-of-sight periodically, which is launched from a spinning black hole in the misaligned direction with respect to the black hole's angular momentum. In addition, we show that this two-component jet model can interpret the radio light curve of the event, especially the re-brightening feature starting ∼100 days after the trigger. From the data we infer that inner jet may have a Lorentz factor of Γ{sub j} ∼ 5.5 and a kinetic energy of E {sub k,} {sub iso} ∼ 3.0 × 10{sup 52} erg, while the outer jet may have a Lorentz factor of Γ{sub j} ∼ 2.5 and a kinetic energy of E{sub k,} {sub iso} ∼ 3.0 × 10{sup 53} erg.

  5. The study of baseline shift error in strong-motion and ground tilting during co-seismic period with collocated GPS and strong-motion observations

    NASA Astrophysics Data System (ADS)

    Tu, Rui; Zhang, Pengfei; Zhang, Rui; Liu, Jinhai; Lu, Xiaochun

    2017-01-01

    Strong-motion's baseline shift error is very difficult to process precisely; it is mainly caused by the tilting, rotation of the ground and environment noises during the co-seismic period. In the study, we first studied how to effectively extract the strong-motion's baseline shift error with GPS observation; this also provides a new way of correcting the baseline shift errors. Then we studied how to retrieve the ground tilting information of the station point with the collocated GPS and strong-motion observations, the information is an important input parameter of rotational seismology. In addition, both experimental result and seismic data show that the baseline shift error is mainly caused by the ground tiling and rotation during the co-seismic period. Also, there is a strong directly proportional relationship between the baseline shift error and ground tilting, of which the proportionality constant is approximately equal to the value of gravitational acceleration of the station.

  6. First continuous ground-based observations of long period oscillations in the vertically resolved wind field of the stratosphere and mesosphere

    NASA Astrophysics Data System (ADS)

    Rüfenacht, Rolf; Hocke, Klemens; Kämpfer, Niklaus

    2016-04-01

    Direct measurements of middle-atmospheric wind oscillations with periods between 5 and 50 days in the altitude range between mid-stratosphere (5 hPa) and upper mesosphere (0.02 hPa) have been made using a novel ground-based Doppler wind radiometer. The oscillations were not inferred from tracer measurements, as the radiometer offers the unique capability of near-continuous horizontal wind profile measurements. Observations from four campaigns at high, middle and low latitudes with an average duration of 10 months have been analyzed. The dominant oscillation has mostly been found to lie in the extra-long period range (20-50 days), while the well-known atmospheric normal modes around 5, 10 and 16 days have also been observed. Comparisons of our results with ECMWF operational analysis data revealed remarkably good agreement below 0.3 hPa but discrepancies above.

  7. 20 CFR 404.1908 - Crediting foreign periods of coverage.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assigned, or the reporting period ends. Example: Country XYZ, which has an annual reporting period... remaining fraction of 3 months, of coverage in a reporting period certified to SSA by the other country's agency. A reporting period used by a foreign country may be one calendar year or some other period...

  8. Spatial analysis of annual mean stable isotopes in precipitation across Japan based on an intensive observation period throughout 2013.

    PubMed

    Ichiyanagi, Kimpei; Tanoue, Masahiro

    2016-01-01

    Spatial distribution of annual mean stable isotopes in precipitation (δ(18)O, δ(2)H) was observed at 56 sites across Japan throughout 2013. Annual mean δ(18)O values showed a strong latitude effect, from -12.4 ‰ in the north to -5.1 ‰ in the south. Annual mean d-excess values ranged from 8 to 21 ‰, and values on the Sea of Japan side in Northern and Eastern Japan were relatively higher than those on the Pacific Ocean side. The local meteoric water line (LMWL) and isotope effects were based on the annual mean values from all sites across Japan as divided into distinct regions: the Sea of Japan side to the Pacific Ocean side and Northeastern to Southwestern Japan. Slopes and intercepts of LMWL ranged from 7.4 to 7.8 and 9.8 to 13.0, respectively. Slopes for latitude, altitude, and temperature effects ranged from -0.27 to -0.48 ‰/°N, -0.0034 to -0.0053 ‰/m, and 0.36 to 0.46 ‰/°C, respectively, with statistically significance at the 99 % level. However, there was no precipitation amount effect. From the result of a multiple regression analysis, the empirical formula of annual mean δ(18)O in precipitation from latitude and altitude for all sites across Japan was determined to be δ(18) O = -0.348 (LAT) - 0.00307 (ALT) + 4.29 (R(2) = 0.59). Slopes for latitude and altitude ranged from - 0.28 to - 0.51, and - 0.0019 to - 0.0045, respectively. Even though site distribution was uneven, these equations are the first trial estimation for annual mean stable isotopes in precipitation across Japan. Further research performed on the monthly basis is required to elucidate factors controlling the spatiotemporal variability of stable isotopes in precipitation across Japan.

  9. Two-day period fluctuation of PMC occurrence over Syowa Station, Antarctica observed by a ground-based lidar and AIM satellite.

    NASA Astrophysics Data System (ADS)

    Nakamura, T.; Suzuki, H.; Tsutsumi, M.; Ejiri, M. K.; Tomikawa, Y.; Abo, M.; Kawahara, T.; Tsuda, T. T.; Nishiyama, T.

    2014-12-01

    A Rayleigh/Raman lidar system has been operated by the Japanese Antarctic Research Expedition (JARE) since February, 2011 (JARE 52nd) in Syowa Station Antarctica (69.0S, 39.5E). The lidar system consists of a pulsed Nd:YAG laser (355nm) as a transmitter and two telescopes with four photo multiplier tubes which are to detect Rayleigh scattered light from low and high atmosphere at 355 nm and N2 Raman emission at 387nm. Polar Mesospheric Cloud (PMC) was detected by the lidar at 22:30UT (+3hr for LT) on Feb 4th, 2011, the first day of a routine operation. This event was the first time to detect PMC over Syowa Station by a lidar [Suzuki et al., Ann. Geophys., 2013]. However, signal to noise ratio (SNR) of the PMC event was not so good due to large shot noises from daytime background signals. Moreover, a receiver system was designed mainly for nighttime observations. In this way, observation of PMC during the midnight sun, which also corresponds to most frequent PMC season, was difficult. Thus, to improve SNR of the PMC observation with the lidar during daytime, a narrow band-pass Fabry-Perot etalon unit has been developed and installed in the receiver system on Dec 2013 by JARE 55th. By using this new system, clear PMC signals were successfully detected under daylight condition during the period of summer operation of JARE55th. During this period of 53 days (from 17 Dec. 2013 to 7 Feb. 2014), only 11 days were with a clear sky and suitable for PMC observation. Thus, it was difficult to study temporal variations on a PMC activity only by using the lidar data. Fortunately, NASA's AIM satellite had passed near Syowa Station and provided with complimentary PMC data during observation gap of the lidar. By combining our lidar data with the AIM/CIPS data, nearly continuous monitoring of PMC variability over Syowa Station was achieved for period between 13th and 18th in January 2014. PMC occurrence with an interval of two days over Syowa Station during the period was clearly

  10. QUASI-PERIODIC SLIPPING MAGNETIC RECONNECTION DURING AN X-CLASS SOLAR FLARE OBSERVED BY THE SOLAR DYNAMICS OBSERVATORY AND INTERFACE REGION IMAGING SPECTROGRAPH

    SciTech Connect

    Li, Ting; Zhang, Jun E-mail: zjun@nao.cas.cn

    2015-05-01

    We first report the quasi-periodic slipping motion of flare loops during an eruptive X-class flare on 2014 September 10. The slipping motion was investigated at a specific location along one of the two ribbons and can be observed throughout the impulsive phase of the flare. The apparent slipping velocity was 20–110 km s{sup −1}, and the associated period was 3–6 minutes. The footpoints of flare loops appeared as small-scale bright knots observed in 1400 Å, corresponding to fine structures of the flare ribbon. These bright knots were observed to move along the southern part of the longer ribbon and also exhibited a quasi-periodic pattern. The Si iv 1402.77 Å line was redshifted by 30–50 km s{sup −1} at the locations of moving knots with a ∼40–60 km s{sup −1} line width, larger than other sites of the flare ribbon. We suggest that the quasi-periodic slipping reconnection is involved in this process and the redshift at the bright knots is probably indicative of reconnection downflow. The emission line of Si iv at the northern part of the longer ribbon also exhibited obvious redshifts of about 10–70 km s{sup −1} in the impulsive phase of the flare, with the redshifts at the outer edges of the ribbon larger than those in the middle. The redshift velocities at post-flare loops reached about 80–100 km s{sup −1} in the transition region.

  11. 46 CFR 169.226 - Periodic inspection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... periodic inspection within 3 months before or after the second or third anniversary of the date of your vessel's Certificate of Inspection. This periodic inspection will take the place of an annual inspection... a time and place which he or she approves. No written application is required. (c) The scope of...

  12. A collection of sub-daily pressure and temperature observations for the early instrumental period with a focus on the "year without a summer" 1816

    NASA Astrophysics Data System (ADS)

    Brugnara, Y.; Auchmann, R.; Brönnimann, S.; Allan, R. J.; Auer, I.; Barriendos, M.; Bergström, H.; Bhend, J.; Brázdil, R.; Compo, G. P.; Cornes, R. C.; Dominguez-Castro, F.; van Engelen, A. F. V.; Filipiak, J.; Holopainen, J.; Jourdain, S.; Kunz, M.; Luterbacher, J.; Maugeri, M.; Mercalli, L.; Moberg, A.; Mock, C. J.; Pichard, G.; Řezníčková, L.; van der Schrier, G.; Slonosky, V.; Ustrnul, Z.; Valente, M. A.; Wypych, A.; Yin, X.

    2015-08-01

    The eruption of Mount Tambora (Indonesia) in April 1815 is the largest documented volcanic eruption in history. It is associated with a large global cooling during the following year, felt particularly in parts of Europe and North America, where the year 1816 became known as the "year without a summer". This paper describes an effort made to collect surface meteorological observations from the early instrumental period, with a focus on the years of and immediately following the eruption (1815-1817). Although the collection aimed in particular at pressure observations, correspondent temperature observations were also recovered. Some of the series had already been described in the literature, but a large part of the data, recently digitised from original weather diaries and contemporary magazines and newspapers, is presented here for the first time. The collection puts together more than 50 sub-daily series from land observatories in Europe and North America and from ships in the tropics. The pressure observations have been corrected for temperature and gravity and reduced to mean sea level. Moreover, an additional statistical correction was applied to take into account common error sources in mercury barometers. To assess the reliability of the corrected data set, the variance in the pressure observations is compared with modern climatologies, and single observations are used for synoptic analyses of three case studies in Europe. All raw observations will be made available to the scientific community in the International Surface Pressure Databank.

  13. Periodicities of the RV Tauri-type pulsating star DF Cygni: A combination of Kepler data with ground-based observations

    NASA Astrophysics Data System (ADS)

    Bódi, A.; Szatmáry, K.; Kiss, L. L.

    2016-11-01

    Context. The RV Tauri stars constitute a small group of classical pulsating stars with some dozen known members in the Milky Way. The light variation is caused predominantly by pulsations, but these alone do not explain the full complexity of light curves. High-quality photometry of RV Tau-type stars is very rare. DF Cygni is the only member of this class of stars in the original Kepler field, hence allowing the most accurate photometric investigation of any RV Tauri star to date. Aims: The main goal is to analyse the periodicities of the RV Tauri-type star DF Cygni by combining four years of high-quality Kepler photometry with almost half a century of visual data collected by the American Association of Variable Star Observers (AAVSO). Methods: Kepler quarters of data were stitched together to minimize the systematic effects of space data. The mean levels have been matched with AAVSO visual data. Both datasets were submitted to Fourier and wavelet analyses, while the stability of the main pulsations was studied with the O-C method and analysis of time-dependent amplitudes. Results: DF Cygni shows very rich behaviour on all timescales. The slow variation has a period of 779.606 d and it has been remarkably coherent during the whole time span of the combined data. On top of the long-term cycles, the pulsations appear with a period of 24.925 d, or the double period of 49.85 d if we take the RV Tau-type alternation of the cycles into account. Both types of light variation significantly fluctuate in time, with a constantly changing interplay of amplitude and phase modulations. Long-period change (i.e. the RVb signature) somewhat resembles the long secondary period (LSP) phenomenon of pulsating red giants, whereas short-period pulsations are very similar to those of the Cepheid variables. Comparing the pulsation patterns with the latest models of Type-II Cepheids, we found evidence of strong non-linear effects that are directly observable in the Kepler light curve.

  14. Evolutionary outcomes for pairs of planets undergoing orbital migration and circularization: second-order resonances and observed period ratios in Kepler's planetary systems

    NASA Astrophysics Data System (ADS)

    Xiang-Gruess, M.; Papaloizou, J. C. B.

    2015-05-01

    In order to study the origin of the architectures of low-mass planetary systems, we perform numerical surveys of the evolution of pairs of coplanar planets in the mass range (1-4) M⊕. These evolve for up to 2 × 107 yr under a range of orbital migration torques and circularization rates assumed to arise through interaction with a protoplanetary disc. Near the inner disc boundary, significant variations of viscosity, interaction with density waves or with the stellar magnetic field could occur and halt migration, but allow circularization to continue. This was modelled by modifying the migration and circularization rates. Runs terminated without an extended period of circularization in the absence of migration torques gave rise to either a collision, or a system close to a resonance. These were mostly first order with a few per cent terminating in second-order resonances. Both planetary eccentricities were small <0.1 and all resonant angles liberated. This type of survey produced only a limited range of period ratios and cannot reproduce Kepler observations. When circularization alone operates in the final stages, divergent migration occurs causing period ratios to increase. Depending on its strength the whole period ratio range between 1 and 2 can be obtained. A few systems close to second-order commensurabilities also occur. In contrast to when arising through convergent migration, resonant trapping does not occur and resonant angles circulate. Thus, the behaviour of the resonant angles may indicate the form of migration that led to near resonance.

  15. SWIFT OBSERVATIONS OF THE HIGH-MASS X-RAY BINARY IGR J16283-4838 UNVEIL A 288 DAY ORBITAL PERIOD

    SciTech Connect

    Cusumano, G.; Segreto, A.; La Parola, V.; D'Aì, A.; Masetti, N.; Tagliaferri, G.

    2013-09-20

    We report on the temporal and spectral properties of the high-mass X-ray binary IGR J16283-4838 in the hard X-ray band. We searched the first 88 months of Swift Burst Alert Telescope (BAT) survey data for long-term periodic modulations. We also investigated the broad band (0.2-150 keV) spectral properties of IGR J16283-4838 complementing the BAT dataset with soft X-ray data from the available Swift-XRT pointed observations. The BAT light curve of IGR J16283-4838 revealed a periodic modulation at P{sub o} = 287.6 ± 1.7 days (with a significance higher than 4 standard deviations). The profile of the light curve folded at P{sub o} shows a sharp peak lasting ∼12 days over a flat plateau. The long-term light curve also shows a ∼300 day interval of prolonged enhanced emission. The observed phenomenology suggests that IGR J16283-4838 has a Be nature, where the narrow periodic peaks and the ∼300 day outburst can be interpreted as Type I and Type II outbursts, respectively. The broad band 0.2-150 keV spectrum can be described with an absorbed power-law and a steepening in the BAT energy range.

  16. Swift Observations of the High-mass X-Ray Binary IGR J16283-4838 Unveil a 288 Day Orbital Period

    NASA Astrophysics Data System (ADS)

    Cusumano, G.; Segreto, A.; La Parola, V.; D'Aì, A.; Masetti, N.; Tagliaferri, G.

    2013-09-01

    We report on the temporal and spectral properties of the high-mass X-ray binary IGR J16283-4838 in the hard X-ray band. We searched the first 88 months of Swift Burst Alert Telescope (BAT) survey data for long-term periodic modulations. We also investigated the broad band (0.2-150 keV) spectral properties of IGR J16283-4838 complementing the BAT dataset with soft X-ray data from the available Swift-XRT pointed observations. The BAT light curve of IGR J16283-4838 revealed a periodic modulation at Po = 287.6 ± 1.7 days (with a significance higher than 4 standard deviations). The profile of the light curve folded at Po shows a sharp peak lasting ~12 days over a flat plateau. The long-term light curve also shows a ~300 day interval of prolonged enhanced emission. The observed phenomenology suggests that IGR J16283-4838 has a Be nature, where the narrow periodic peaks and the ~300 day outburst can be interpreted as Type I and Type II outbursts, respectively. The broad band 0.2-150 keV spectrum can be described with an absorbed power-law and a steepening in the BAT energy range.

  17. High energy X-ray observations of CYG X-3 from from OSO-8: Further evidence of a 34.1 day period

    NASA Technical Reports Server (NTRS)

    Dolan, J. F.; Crannell, C. J.; Dennis, B. R.; Frost, K. J.; Orwig, L. E.

    1981-01-01

    The X-ray source Cyg X-3 (=4U2030+40) was observed with the high energy X-ray spectrometer on OSO-8 for two weeks in 1975 and in 1976 and for one week in 1977. No change in spectral shape and intensity above 23 keV was observed from year to year. No correlation is observed between the source's intensity and the phase of the 34.1 day period discovered by Molteni, et al. (1980). The pulsed fraction of the 4.8 hour light curve between 23 and 73 keV varies from week to week, however, and the magnitude of the pulsed fraction appears to be correlated with the 34.1 day phase. No immediate explanation of this behavior is apparent in terms of previously proposed models of the source.

  18. Diet and gender are important factors modulating low frequency EEG activity during processing of language sounds in 3 month old infants

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Little is known about how early postnatal diet affects brain processes related to cognitive function in healthy infants. To address this question we examined EEG activity recorded from 3 month old infants [breastfed (BF: n = 104, 55 males), milk-based formula fed (MF: n = 114, 57 males) or soy for...

  19. Complete sternal cleft — A rare congenital malformation and its repair in a 3-month-old boy: A case report

    PubMed Central

    Kothari, Paras; Gupta, Abhaya; Patil, Prashant S.; Kekre, Geeta; Kamble, Ravi; Dikshit, Kiran Vishesh

    2016-01-01

    Complete midline sternal cleft is a rare congenital anomaly resulting from failed midline ventral fusion of the sternal bars. Very few cases of complete sternal cleft have been described in literature. We present a case of complete sternal cleft in a 3-month-old child. The patient underwent primary closure of the defect using stainless steel wires. PMID:27046980

  20. [Dental pain in the previous 3 months in adolescents and Family Health Strategy: the comparison between two areas with different to oralhealth care approaches].

    PubMed

    Carvalho, Jefferson Calixto; Rebelo, Maria Augusta Bessa; Vettore, Mario Vianna

    2011-10-01

    This study sought to compare the prevalence and intensity of dental pain in the last 3 months in adolescents living in two areas within the scope of Family Health Strategy with different to oralhealth care approaches. A cross-sectional study was conducted with 300 adolescents selected from public schools in the city of Manaus, Brazil. Adolescents living in an area with an Oral Health Team in which of health promotion is predominant (Group I, N = 150) were compared with those living in an area in which only dental treatment is offered (Group II, N = 150). Demographic and socio-economic characteristics, oral health-related behavior and use of dental services were gathered. Prevalence and intensity of dental pain in the last 3 months was assessed using a tested and validated Likert scale. The mean age of the participants was 12.9 ± 0.8 years, of which 46.7% were male. The prevalence of dental pain in the last 3 months was 33.7%, and did not differ between Groups I and II (P > 0.05). Medium to high intensity dental pain in the last 3 months was associated with Group II (OR: 2.11 [CI95 %=1.17-3.81]), after adjustment for covariates. Adolescents living in the area where only dental treatment is offered were more prone to severe dental pain compared to those living in the area where health programs are predominant.

  1. Cross-Race Preferences for Same-Race Faces Extend beyond the African versus Caucasian Contrast in 3-Month-Old Infants

    ERIC Educational Resources Information Center

    Kelly, David J.; Liu, Shaoying; Ge, Liezhong; Quinn, Paul C.; Slater, Alan M.; Lee, Kang; Liu, Qinyao; Pascalis, Olivier

    2007-01-01

    A visual preference procedure was used to examine preferences among faces of different ethnicities (African, Asian, Caucasian, and Middle Eastern) in Chinese 3-month-old infants exposed only to Chinese faces. The infants demonstrated a preference for faces from their own ethnic group. Alongside previous results showing that Caucasian infants…

  2. Observation of a periodic array of flux-closure quadrants in strained ferroelectric PbTiO3 films

    SciTech Connect

    Tang, Y. L.; Zhu, Y. L; Ma, Xiuliang; Borisevich, Albina Y; Morozovska, A. N.; Eliseev, Eugene; Wang, W. Y; Wang, Yujia; Xu, Y. B.; Zhang, Z. D.; Pennycook, Stephen J

    2015-05-01

    Nanoscale ferroelectrics are expected to exhibit various exotic domain configurations, such as the full flux-closure pattern that is well known in ferromagnetic materials. Here we observe not only the atomic morphology of the flux-closure quadrant but also a periodic array of flux closures in ferroelectric PbTiO3 films, mediated by tensile strain on a GdScO3 substrate. Using aberration-corrected scanning transmission electron microscopy, we directly visualize an alternating array of clockwise and counterclockwise flux closures, whose periodicity depends on the PbTiO3 film thickness. In the vicinity of the core, the strain is sufficient to rupture the lattice, with strain gradients up to 109 per meter. We found engineering strain at the nanoscale may facilitate the development of nanoscale ferroelectric devices.

  3. Climate and polar motion during the GRACE observing period: 2002-2015: Implications for decadal scale oscillations during the 20th Century

    NASA Astrophysics Data System (ADS)

    Ivins, Erik; Adhikari, Surendra; Larour, Eric

    2016-04-01

    The motion of the Earth's pole in space has been observed with great accuracy for the last 115 years. The angular variations of the pole position away from its mean are a well explained at annual and 434-day periods. Variations at annual periods are caused by changes in the mass and angular momentum forced by all Earth surface changes that have near seasonality. The 434-day period is explained as a resonance between the cumulative driving forces having periods near the Chandler wobble free eigenmode of the Earth and is well understood theoretically. The Earth also has a longer-term drift that is explained primarily as a response to the ice age changes in the moments of inertial of the Earth. However, there has been a long-standing search for the origins of pole variations that have a period near 10 years. Using GRACE space gravimetry we show that ice mass losses from Greenland and Antarctica, and when combined with changes in continental hydrology, explain almost all the main features of interannual time scale polar wander. The discovery has broad interdisciplinary implications, as we show that decadal scale pole variations are directly linked to global changes continental water. The energy sources for these pole position changes are, therefore, likely to be associated with decadal scale ocean and atmospheric oscillations that also drive 20th Century on-land wet-dry oscillations at decadal-scale across the globe. Variability in pole position, therefore, offers a tool for assessing past stability of our climate, and for the future, now faced with an increased intensity in the water cycle and more vulnerable to ice sheet instability.

  4. Acute and 3-month effects of microcrystalline hydroxyapatite, calcium citrate and calcium carbonate on serum calcium and markers of bone turnover: a randomised controlled trial in postmenopausal women.

    PubMed

    Bristow, Sarah M; Gamble, Greg D; Stewart, Angela; Horne, Lauren; House, Meaghan E; Aati, Opetaia; Mihov, Borislav; Horne, Anne M; Reid, Ian R

    2014-11-28

    Ca supplements are used for bone health; however, they have been associated with increased cardiovascular risk, which may relate to their acute effects on serum Ca concentrations. Microcrystalline hydroxyapatite (MCH) could affect serum Ca concentrations less than conventional Ca supplements, but its effects on bone turnover are unclear. In the present study, we compared the acute and 3-month effects of MCH with conventional Ca supplements on concentrations of serum Ca, phosphate, parathyroid hormone and bone turnover markers. We randomised 100 women (mean age 71 years) to 1 g/d of Ca as citrate or carbonate (citrate-carbonate), one of two MCH preparations, or a placebo. Blood was sampled for 8 h after the first dose, and after 3 months of daily supplementation. To determine whether the acute effects changed over time, eight participants assigned to the citrate dose repeated 8 h of blood sampling at 3 months. There were no differences between the citrate and carbonate groups, or between the two MCH groups, so their results were pooled. The citrate-carbonate dose increased ionised and total Ca concentrations for up to 8 h, and this was not diminished after 3 months. MCH increased ionised Ca concentrations less than the citrate-carbonate dose; however, it raised the concentrations of phosphate and the Ca-phosphate product. The citrate-carbonate and MCH doses produced comparable decreases in bone resorption (measured as serum C-telopeptide (CTX)) over 8 h and bone turnover (CTX and procollagen type-I N-terminal propeptide) at 3 months. These findings suggest that Ca preparations, in general, produce repeated sustained increases in serum Ca concentrations after ingestion of each dose and that Ca supplements with smaller effects on serum Ca concentrations may have equivalent efficacy in suppressing bone turnover.

  5. Regional modeling of tropospheric NO2 vertical column density over East Asia during the period 2000-2010: comparison with multisatellite observations

    NASA Astrophysics Data System (ADS)

    Itahashi, S.; Uno, I.; Irie, H.; Kurokawa, J.-I.; Ohara, T.

    2014-04-01

    Satellite observations of the tropospheric NO2 vertical column density (VCD) are closely correlated to, and thus can be used to estimate, surface NOx emissions. In this study, the NO2 VCD simulated by a regional chemical transport model with emissions data from the updated Regional Emission inventory in ASia (REAS) version 2.1 were validated through comparison with multisatellite observations during the period 2000-2010. Rapid growth in NO2 VCD (~11% year-1) driven by the expansion of anthropogenic NOx emissions was identified above the central eastern China (CEC) region, except for the period during the economic downturn. In contrast, slightly decreasing trends (~2% year-1) were identified above Japan accompanied by a decline in anthropogenic emissions. To systematically compare the modeled NO2 VCD, we estimated sampling bias and the effect of applying the averaging kernel information, with particular focus on the SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY (SCIAMACHY) data. Using the updated REAS, the modeled NO2 VCD reasonably reproduced annual trends observed by multisatellites, suggesting that the rate of increase of NOx emissions estimated by the updated REAS inventory would be robust. Province-scale revision of emissions above CEC is needed to further refine emission inventories. Based on the close linear relationship between modeled and observed NO2 VCD and anthropogenic NOx emissions, NOx emissions in 2009 and 2010, which were not covered by the updated REAS inventory, were estimated. NOx emissions from anthropogenic sources in China in 2009 and 2010 were determined to be 26.4 and 28.5 Tg year-1, respectively, indicating that NOx emissions increased more than twofold between 2000 and 2010. This increase reflected the strong growth of anthropogenic emissions in China following the rapid recovery from the economic downturn from late 2008 until mid-2009. Our method consists of simple estimations from satellite observations and

  6. Mortality coefficients among personnel of radiochemical plants of {open_quotes}Mayak{close_quotes}-Combine for 40-year period of observation

    SciTech Connect

    Koshurnikova, N.A.; Komleva, N.S.; Baisogolov, G.D.

    1993-12-31

    The results of the epidemiological research, conducted among the personnel of the radiochemical plants of {open_quotes}Mayak{close_quotes}. Combine are as follows: during the 40-year-period of observation the mortality rate from all and separate causes, except age, is lower, than the expected one, which is calculated on the basis of the National Statistics. Oncological mortality rate is reliably higher, than the expected one, which is conditioned by the high frequency of lung cancer and leucaemia. Internal {alpha}-irradiation plays the leading role in the induction of lung cancer, and the increase of mortality rate from leukemia is closely connected with external {gamma}-irradiation.

  7. Observation of three-dimensional structures of quasi-periodic echoes associated with mid-latitude sporadic-E layers by MU radar ultra-multi-channel system

    NASA Astrophysics Data System (ADS)

    Saito, S.; Yamamoto, M.; Hashiguchi, H.; Maegawa, A.

    2006-07-01

    Quasi-periodic (QP) backscatter observed by VHF radars associated with the mid-latitude Sporadic-E (Es) layers is characterized by distinct striations on range-time-intensity (RTI) plots. Two competing models claim to explain the structure of unstable regions that scatter the radar waves: horizontally drifting patches at an almost constant altitude and unstable regions elongated in altitude along the geomagnetic field line. We have conducted interferometric imaging observations of QP radar echoes to investigate spatial structures of QP echoes, precisely. Kyoto University's newly developed ultra-multi-channel receiving system of middle and upper atmosphere (MU) radar was used. We used 19 independent channels for the radar imaging, and determined the three-dimensional structure and the motion of the QP echoes. During the observation from 30 May to 02 June 2005, well-defined QP echoes were observed on the nights of 31 May, 01 June, and 02 June 2005. Some of QP echoes were found at altitudes higher than 120 km and appeared to descend in altitude as they approached the radar. This result suggests that backscatter regions are developed along the geomagnetic field line from Es layer altitudes to as high as 130 km and that the fluctuations in plasma density and electric field observed by Pfaff et al. (2005) using in-situ measurements form a part of QP echoes.

  8. Explorer 45 (S 3-A) observations of the magnetosphere and magnetopause during the 4-5 August 1972, magnetic storm period

    NASA Technical Reports Server (NTRS)

    Hoffman, R. A.; Cahill, L. J., Jr.; Anderson, R. R.; Maynard, N. C.; Smith, P. H.; Fritz, T. A.; Williams, D. J.; Konradi, A.; Gurnett, D. A.

    1974-01-01

    The Explorer 45 satellite performed extensive field and particle measurements in the heart of the magnetosphere during the double magnetic storm period of August 4-5, 1972. Both ground level magnetic records and the magnetic field deformations measured along the orbit by the satellite indicated the existence of only a moderate ring current. This was confirmed by the measurements of the total proton energy density less than those observed during the December 1971 and June 1972 magnetic storms. The plasmapause in the noon quadrant was eroded continuously from the onset of the first storm at the beginning of August 4 to an altitude below L = 2.07 at about 18 hours on August 5. During the orbit containing the second sudden commencement a large amount of low frequency electric and magnetic field noise was encountered throughout the entire orbit. A noteworthy observation during this orbit was the contraction of the magnetopause to distances inside the satellite at L = 5.2.

  9. Comparison of IRI-2012 with JASON-1 TEC and incoherent scatter radar observations during the 2008-2009 solar minimum period

    NASA Astrophysics Data System (ADS)

    Ji, Eun-Young; Jee, Geonhwa; Lee, Changsup

    2016-08-01

    The 2008-2009 solar minimum period was unprecedentedly deep and extended. We compare the IRI-2012 with global TEC data from JASON-1 satellite and with electron density profiles observed from incoherent scatter radars (ISRs) at middle and high latitudes for this solar minimum period. Global daily mean TECs are calculated from JASON-1 TECs to compare with the corresponding IRI TECs during the 2008-2009 period. It is found that IRI underestimates the global daily mean TEC by about 20-50%. The comparison of global TEC maps further reveals that IRI overall underestimates TEC for the whole globe except for the low-latitude region around the equatorial anomaly, regardless of season. The underestimation is particularly strong in the nighttime winter hemisphere where the ionosphere seems to almost disappear in IRI. In the daytime equatorial region, however, the overestimation of IRI is mainly due to the misrepresentation of the equatorial anomaly in IRI. Further comparison with ISR electron density profiles confirms the significant underestimation of IRI at night in the winter hemisphere.

  10. Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331.

    PubMed

    Mitchell, Hannah-Rose; Lu, Xiaomin; Myers, Regina M; Sung, Lillian; Balsamo, Lyn M; Carroll, William L; Raetz, Elizabeth; Loh, Mignon L; Mattano, Leonard A; Winick, Naomi J; Devidas, Meenakshi; Hunger, Stephen P; Maloney, Kelly; Kadan-Lottick, Nina S

    2016-01-15

    Standard risk acute lymphoblastic leukemia (SR-ALL) has high cure rates, but requires 2-3 years of therapy. We aimed to (i) prospectively evaluate health-related quality of life (HRQOL) during and after SR-ALL therapy, and (ii) identify associated predictors. Parents of 160 SR-ALL patients enrolled on Children's Oncology Group (COG) therapeutic trial AALL0331 at 31 sites completed the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales (physical, emotional and social functioning) and Family Assessment Device-General Functioning (FAD-GF) at 1, 6 and 12 months after diagnosis, and 3 months post-therapy. Mean PedsQL scores in physical, emotional and social functioning were impaired 1 month after diagnosis but steadily improved. Three months post-therapy, impaired physical and social functioning was observed in 27.8 and 25.8% of patients, respectively. In repeated-measures analysis, problematic family functioning predicted emotional (OR = 1.85, 95% CI 1.03-3.34) and social (OR = 1.99, 95% CI 1.21-3.27) impairment. Larger household size was associated with social impairment (OR = 1.21, 95% CI 1.02-1.45). Adverse neurological event(s) during therapy predicted post-therapy physical (OR = 5.17, 95% CI 1.61-16.63) and social (OR = 8.17, 95% CI 1.19-56.16) impairment. HRQOL 1 month after diagnosis was not predictive of HRQOL 3 months after therapy completion. In conclusion, children with SR-ALL experience considerable impairment in HRQOL at the end of induction, but rapidly improve. However, many still experience physical and social impairment 3 months post-therapy, suggesting a role for continued family and physical functioning support. Longer follow-up is needed to determine if post-therapy deficits change over time.

  11. Operation of a digital seismic network on Mount St. Helens volcano and observations of long period seismic events that originate under the volcano

    SciTech Connect

    Fehler, M.; Chouet, B.

    1982-09-01

    A 9 station digital seismic array was operated on Mount St. Helens volcano in Washington State during 1981. One of the stations was placed inside the crater of the volcano, six were located on the flanks of the volcano within two km of the crater and two were approximately ten km from the crater. Four of the instruments recorded three components of motion and the remaining five recorded only the vertical component. A one day experiment was carried out during which the crater monitoring seismometer was complimented by the addition of two ink recording instruments. During the one day experiment six observers recorded times of rockfall, felt-earthquake occurrences, and changes in steam emissions from the dome in the crater. Using information obtained during the one day experiment seismic events recorded by the digital instruments were classified as earthquakes, rockfalls, helicopter noise and a type of event that is unique to volcanoes which is called long period. Waveforms of these long period events have a duration of up to 30 seconds and a spectrum that is peaked at approximately 2 Hz. The frequency at which the peak in the spectrum occurs is nearly the same at all stations which means that the unique waveform of long period events is due to a source effect, not a path effect. The peak frequency is fairly insensitive to the amplitude of the signal which means that the size of the source region is constant, independent of the signal amplitude. Long period events were not felt and were accompanied by no visible changes inside the crater which lead to the conclusion that they are some sort of seismic disturbance generated inside the Volcano.

  12. Quasi-periodic oscillations in short recurring bursts of magnetars SGR 1806–20 and SGR 1900+14 observed with RXTE

    SciTech Connect

    Huppenkothen, D.; Heil, L. M.; Watts, A. L.; Göğüş, E.

    2014-11-10

    Quasi-periodic oscillations (QPOs) observed in the giant flares of magnetars are of particular interest due to their potential to open up a window into the neutron star interior via neutron star asteroseismology. However, only three giant flares have been observed. We therefore make use of the much larger data set of shorter, less energetic recurrent bursts. Here, we report on a search for QPOs in a large data set of bursts from the two most burst-active magnetars, SGR 1806-20 and SGR 1900+14, observed with Rossi X-ray Timing Explorer. We find a single detection in an averaged periodogram comprising 30 bursts from SGR 1806–20, with a frequency of 57 Hz and a width of 5 Hz, remarkably similar to a giant flare QPO observed from SGR 1900+14. This QPO fits naturally within the framework of global magneto-elastic torsional oscillations employed to explain giant flare QPOs. Additionally, we uncover a limit on the applicability of Fourier analysis for light curves with low background count rates and strong variability on short timescales. In this regime, standard Fourier methodology and more sophisticated Fourier analyses fail in equal parts by yielding an unacceptably large number of false-positive detections. This problem is not straightforward to solve in the Fourier domain. Instead, we show how simulations of light curves can offer a viable solution for QPO searches in these light curves.

  13. Comparisons of observed and modeled OH and HO2 concentrations during the ambient measurement period of the HOxComp field campaign

    NASA Astrophysics Data System (ADS)

    Kanaya, Y.; Hofzumahaus, A.; Dorn, H.-P.; Brauers, T.; Fuchs, H.; Holland, F.; Rohrer, F.; Bohn, B.; Tillmann, R.; Wegener, R.; Wahner, A.; Kajii, Y.; Miyamoto, K.; Nishida, S.; Watanabe, K.; Yoshino, A.; Kubistin, D.; Martinez, M.; Rudolf, M.; Harder, H.; Berresheim, H.; Elste, T.; Plass-Dülmer, C.; Stange, G.; Kleffmann, J.; Elshorbany, Y.; Schurath, U.

    2012-03-01

    was characterized by low isoprene concentrations (∼0.5 ppb) and OH reactivity that was well explained by the observed species, especially before noon. For this selected period, as opposed to the general behavior, the model tended to underestimate HO2(*). We found that this tendency is associated with high NOx concentrations, suggesting that some HO2 production or regeneration processes under high NOx conditions were being overlooked; this might require revision of ozone production regimes.

  14. Auroral activities observed by SNPP VIIRS day/night band during a long period geomagnetic storm event on April 29-30, 2014

    NASA Astrophysics Data System (ADS)

    Shao, Xi; Cao, Changyong; Liu, Tung-chang; Zhang, Bin; Wang, Wenhui; Fung, Shing F.

    2015-10-01

    The Day/Night Band (DNB) of the Visible Infrared Imaging Radiometer Suite (VIIRS) onboard Suomi-NPP represents a major advancement in night time imaging capabilities. The DNB senses radiance that can span 7 orders of magnitude in one panchromatic (0.5-0.9 μm) reflective solar band and provides imagery of clouds and other Earth features over illumination levels ranging from full sunlight to quarter moon. When the satellite passes through the day-night terminator, the DNB sensor is affected by stray light due to solar illumination on the instrument. With the implementation of stray light correction, stray light-corrected DNB images enable the observation of aurora occurred in the high latitude regions during geomagnetic storms. In this paper, DNB observations of auroral activities are analyzed during a long period (> 20 hours) of geomagnetic storm event occurred on Apr. 29-30, 2014. The storm event has the Bz component of interplanetary magnetic field (IMF) pointing southward for more than 20 hours. During this event, the geomagnetic storm index Dst reached -67 nT and the geomagnetic auroral electrojet (AE) index increased and reached as high as 1200 nT with large amplitude fluctuations. The event occurred during new moon period and DNB observation has minimum moon light contamination. During this event, auroras are observed by DNB for each orbital pass on the night side (~local time 1:30am) in the southern hemisphere. DNB radiance data are processed to identify regions of aurora during each orbital pass. The evolution of aurora is characterized with time series of the poleward and equatorward boundary of aurora, area, peak radiance and total light emission of the aurora in DNB observation. These characteristic parameters are correlated with solar wind and geomagnetic index parameters. It is found that the evolution of total area-integrated radiance of auroral region over the southern hemisphere correlated well with the ground geomagnetic AE index with correlation

  15. A 3-Month Randomized Controlled Pilot Trial of a Patient-Centered, Computer-Based Self-Monitoring System for the Care of Type 2 Diabetes Mellitus and Hypertension.

    PubMed

    Or, Calvin; Tao, Da

    2016-04-01

    This study was performed to evaluate the effects of a patient-centered, tablet computer-based self-monitoring system for chronic disease care. A 3-month randomized controlled pilot trial was conducted to compare the use of a computer-based self-monitoring system in disease self-care (intervention group; n = 33) with a conventional self-monitoring method (control group; n = 30) in patients with type 2 diabetes mellitus and/or hypertension. The system was equipped with a 2-in-1 blood glucose and blood pressure monitor, a reminder feature, and video-based educational materials for the care of the two chronic diseases. The control patients were given only the 2-in-1 monitor for self-monitoring. The outcomes reported here included the glycated hemoglobin (HbA1c) level, fasting blood glucose level, systolic blood pressure, diastolic blood pressure, chronic disease knowledge, and frequency of self-monitoring. The data were collected at baseline and at 1-, 2-, and 3-month follow-up visits. The patients in the intervention group had a significant decrease in mean systolic blood pressure from baseline to 1 month (p < 0.001) and from baseline to 3 months (p = 0.043) compared with the control group. Significant improvements in the mean diastolic blood pressure were seen in the intervention group compared with the control group after 1 month (p < 0.001) and after 2 months (p = 0.028), but the change was not significant after 3 months. No significant differences were observed between the groups in the fasting blood glucose level, the HbA1c level, or chronic disease knowledge. The frequency of self-monitoring of blood glucose level and blood pressure was similar in both groups. The performances of the tablet computer-assisted and conventional disease self-monitoring appear to be useful to support/maintain blood pressure and diabetes control. The beneficial effects of the use of electronic self-care resources and support provided via mobile technologies require further

  16. Field Observation of Heterogeneous Formation of Dicarboxylic acids, Keto-carboxylic acids, α-Dicarbonyls and Nitrate in Xi'an, China during Asian dust storm periods

    NASA Astrophysics Data System (ADS)

    Wang, G.; Wang, J.; Ren, Y.; Li, J.

    2015-12-01

    To understand the formation mechanism of secondary organic aerosols (SOA) on dust surfaces, this study investigated the concentrations and compositions of dicarboxylic acids (C2-C11), keto-carboxylic acids (C3-C7), α-dicarbonyls and inorganic ions in size-segregated aerosols (9-stages) collected in Xi'an, China during the nondust storm and dust storm periods of 2009 and 2011. During the events the ambient particulate dicarboxylic acids were 932-2240 ng m-3, which are comparable and even higher than those in nondust periods. Molecular compositions of the above SOA are similar to those in nondust periods with oxalic acid being the leading species. In the presence of the dust storms, all the above mentioned SOA species in Xi'an were predominantly enriched on the coarse particles (>2.1μm), and oxalic acid well correlated with NO3- (R2=0.72, p<0.001) rather than SO42-.This phenomenon differs greatly from the SOA in any other nondust period that is characterized by an enrichment of oxalic acid in fine particles and a strong correlation of oxalic acid with SO42-. Our results further demonstrate that NO3- in the dust periods in Xi'an was mostly derived from secondary oxidation, whereas SO42- during the events was largely derived from surface soil of Gobi deserts. We propose a formation pathway to explain these observations, in which nitric acid and/or nitrogen oxides react with dust to produce Ca(NO3)2 and form a liquid phase on the surface of dust aerosols via water vapor-absorption of Ca(NO3)2, followed by a partitioning of the gas-phase water-soluble organic precursors (e.g.,glyoxal and methylglyoxal) into the aqueous-phase and a subsequent oxidation into oxalic acid. To the best of our knowledge, we found for the first time the enrichment of glyoxal and methylglyoxal on dust surface. Our data suggest an important role of nitrate in the heterogeneous formation process of SOA on the surface of Asian dust.

  17. Evidence of low-latitude daytime large-scale traveling ionospheric disturbances observed by high-frequency multistatic backscatter sounding system during a geomagnetically quiet period

    NASA Astrophysics Data System (ADS)

    Zhou, Chen; Zhao, Zhengyu; Yang, Guobin; Chen, Gang; Hu, Yaogai; Zhang, Yuannong

    2012-06-01

    Observations from the high-frequency multistatic backscatter sounding radars on a geomagnetically quiet day (minimum Dst = -14 nT) captured the anti-equatorward propagation of daytime large-scale traveling ionospheric disturbance (LSTID) at the low-latitude regions. The observed LSTID was characterized approximately by a meridional propagation speed of 347 ± 78 m/s and azimuthal angle of -4.7 ± 27.6° (counterclockwise from north), with a period of 76 min and a wavelength of 1583 ± 354 km by means of maximum entropy cross-spectral analysis. Vertical phase velocity was also evaluated to be <˜42 m/s through the Doppler measurements. These results provide evidence that the low-latitude ionosphere can undergo large-scale perturbations even under geomagnetically quiet conditions. We suggest that this observed LSTID could be due to the secondary gravity waves from thermospheric body forces created from the dissipation of primary gravity waves from deep tropospheric convection.

  18. Beam-induced and cosmic-ray backgrounds observed in the ATLAS detector during the LHC 2012 proton-proton running period

    NASA Astrophysics Data System (ADS)

    Aad, G.; Abbott, B.; Abdallah, J.; Abdinov, O.; Abeloos, B.; Aben, R.; Abolins, M.; AbouZeid, O. S.; Abraham, N. L.; Abramowicz, H.; Abreu, H.; Abreu, R.; Abulaiti, Y.; Acharya, B. S.; Adamczyk, L.; Adams, D. L.; Adelman, J.; Adomeit, S.; Adye, T.; Affolder, A. A.; Agatonovic-Jovin, T.; Agricola, J.; Aguilar-Saavedra, J. A.; Ahlen, S. P.; Ahmadov, F.; Aielli, G.; Akerstedt, H.; Åkesson, T. P. A.; Akimov, A. V.; Alberghi, G. L.; Albert, J.; Albrand, S.; Alconada Verzini, M. J.; Aleksa, M.; Aleksandrov, I. N.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alhroob, M.; Aliev, M.; Alimonti, G.; Alison, J.; Alkire, S. P.; Allbrooke, B. M. M.; Allen, B. W.; Allport, P. P.; Aloisio, A.; Alonso, A.; Alonso, F.; Alpigiani, C.; Alvarez Gonzalez, B.; Álvarez Piqueras, D.; Alviggi, M. G.; Amadio, B. T.; Amako, K.; Amaral Coutinho, Y.; Amelung, C.; Amidei, D.; Amor Dos Santos, S. P.; Amorim, A.; Amoroso, S.; Amram, N.; Amundsen, G.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, G.; Anders, J. K.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Angelidakis, S.; Angelozzi, I.; Anger, P.; Angerami, A.; Anghinolfi, F.; Anisenkov, A. V.; Anjos, N.; Annovi, A.; Antonelli, M.; Antonov, A.; Antos, J.; Anulli, F.; Aoki, M.; Aperio Bella, L.; Arabidze, G.; Arai, Y.; Araque, J. P.; Arce, A. T. H.; Arduh, F. A.; Arduini, G.; Arguin, J.-F.; Argyropoulos, S.; Arik, M.; Armbruster, A. J.; Armitage, L. J.; Arnaez, O.; Arnold, H.; Arratia, M.; Arslan, O.; Artamonov, A.; Artoni, G.; Artz, S.; Asai, S.; Asbah, N.; Ashkenazi, A.; Åsman, B.; Asquith, L.; Assamagan, K.; Astalos, R.; Atkinson, M.; Atlay, N. B.; Augsten, K.; Avolio, G.; Axen, B.; Ayoub, M. K.; Azuelos, G.; Baak, M. A.; Baas, A. E.; Baca, M. J.; Bachacou, H.; Bachas, K.; Backes, M.; Backhaus, M.; Bagiacchi, P.; Bagnaia, P.; Bai, Y.; Baines, J. T.; Baker, O. K.; Baldin, E. M.; Balek, P.; Balestri, T.; Balli, F.; Balunas, W. K.; Banas, E.; Banerjee, Sw.; Bannoura, A. A. E.; Barak, L.; Barberio, E. L.; Barberis, D.; Barbero, M.; Barillari, T.; Barklow, T.; Barlow, N.; Barnes, S. L.; Barnett, B. M.; Barnett, R. M.; Barnovska, Z.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barranco Navarro, L.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Bartoldus, R.; Barton, A. E.; Bartos, P.; Basalaev, A.; Bassalat, A.; Basye, A.; Bates, R. L.; Batista, S. J.; Batley, J. R.; Battaglia, M.; Bauce, M.; Bauer, F.; Bawa, H. S.; Beacham, J. B.; Beattie, M. D.; Beau, T.; Beauchemin, P. H.; Bechtle, P.; Beck, H. P.; Becker, K.; Becker, M.; Beckingham, M.; Becot, C.; Beddall, A. J.; Beddall, A.; Bednyakov, V. A.; Bedognetti, M.; Bee, C. P.; Beemster, L. J.; Beermann, T. A.; Begel, M.; Behr, J. K.; Belanger-Champagne, C.; Bell, A. S.; Bella, G.; Bellagamba, L.; Bellerive, A.; Bellomo, M.; Belotskiy, K.; Beltramello, O.; Belyaev, N. L.; Benary, O.; Benchekroun, D.; Bender, M.; Bendtz, K.; Benekos, N.; Benhammou, Y.; Benhar Noccioli, E.; Benitez, J.; Benitez Garcia, J. A.; Benjamin, D. P.; Bensinger, J. R.; Bentvelsen, S.; Beresford, L.; Beretta, M.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Berghaus, F.; Beringer, J.; Berlendis, S.; Bernard, N. R.; Bernius, C.; Bernlochner, F. U.; Berry, T.; Berta, P.; Bertella, C.; Bertoli, G.; Bertolucci, F.; Bertram, I. A.; Bertsche, C.; Bertsche, D.; Besjes, G. J.; Bessidskaia Bylund, O.; Bessner, M.; Besson, N.; Betancourt, C.; Bethke, S.; Bevan, A. J.; Bhimji, W.; Bianchi, R. M.; Bianchini, L.; Bianco, M.; Biebel, O.; Biedermann, D.; Bielski, R.; Biesuz, N. V.; Biglietti, M.; Bilbao De Mendizabal, J.; Bilokon, H.; Bindi, M.; Binet, S.; Bingul, A.; Bini, C.; Biondi, S.; Bjergaard, D. M.; Black, C. W.; Black, J. E.; Black, K. M.; Blackburn, D.; Blair, R. E.; Blanchard, J.-B.; Blanco, J. E.; Blazek, T.; Bloch, I.; Blocker, C.; Blum, W.; Blumenschein, U.; Blunier, S.; Bobbink, G. J.; Bobrovnikov, V. S.; Bocchetta, S. S.; Bocci, A.; Bock, C.; Boehler, M.; Boerner, D.; Bogaerts, J. A.; Bogavac, D.; Bogdanchikov, A. G.; Bohm, C.; Boisvert, V.; Bold, T.; Boldea, V.; Boldyrev, A. S.; Bomben, M.; Bona, M.; Boonekamp, M.; Borisov, A.; Borissov, G.; Bortfeldt, J.; Bortoletto, D.; Bortolotto, V.; Bos, K.; Boscherini, D.; Bosman, M.; Bossio Sola, J. D.; Boudreau, J.; Bouffard, J.; Bouhova-Thacker, E. V.; Boumediene, D.; Bourdarios, C.; Boutle, S. K.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bracinik, J.; Brandt, A.; Brandt, G.; Brandt, O.; Bratzler, U.; Brau, B.; Brau, J. E.; Braun, H. M.; Breaden Madden, W. D.; Brendlinger, K.; Brennan, A. J.; Brenner, L.; Brenner, R.; Bressler, S.; Bristow, T. M.; Britton, D.; Britzger, D.; Brochu, F. M.; Brock, I.; Brock, R.; Brooijmans, G.; Brooks, T.; Brooks, W. K.; Brosamer, J.; Brost, E.; Broughton, J. H.; Bruce, R.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruneliere, R.; Bruni, A.; Bruni, G.; Brunt, BH; Bruschi, M.; Bruscino, N.; Bryant, P.; Bryngemark, L.; Buanes, T.; Buat, Q.; Buchholz, P.; Buckley, A. G.; Budagov, I. A.; Buehrer, F.; Bugge, M. K.; Bulekov, O.; Bullock, D.; Burckhart, H.; Burdin, S.; Burgard, C. D.; Burghgrave, B.; Burka, K.; Burke, S.; Burmeister, I.; Busato, E.; Büscher, D.; Büscher, V.; Bussey, P.; Butler, J. M.; Butt, A. I.; Buttar, C. M.; Butterworth, J. M.; Butti, P.; Buttinger, W.; Buzatu, A.; Buzykaev, A. R.; Cabrera Urbán, S.; Caforio, D.; Cairo, V. M.; Cakir, O.; Calace, N.; Calafiura, P.; Calandri, A.; Calderini, G.; Calfayan, P.; Caloba, L. P.; Calvet, D.; Calvet, S.; Calvet, T. P.; Camacho Toro, R.; Camarda, S.; Camarri, P.; Cameron, D.; Caminal Armadans, R.; Camincher, C.; Campana, S.; Campanelli, M.; Campoverde, A.; Canale, V.; Canepa, A.; Cano Bret, M.; Cantero, J.; Cantrill, R.; Cao, T.; Capeans Garrido, M. D. M.; Caprini, I.; Caprini, M.; Capua, M.; Caputo, R.; Carbone, R. M.; Cardarelli, R.; Cardillo, F.; Carli, T.; Carlino, G.; Carminati, L.; Caron, S.; Carquin, E.; Carrillo-Montoya, G. D.; Carter, J. R.; Carvalho, J.; Casadei, D.; Casado, M. P.; Casolino, M.; Casper, D. W.; Castaneda-Miranda, E.; Castelli, A.; Castillo Gimenez, V.; Castro, N. F.; Catinaccio, A.; Catmore, J. R.; Cattai, A.; Caudron, J.; Cavaliere, V.; Cavallaro, E.; Cavalli, D.; Cavalli-Sforza, M.; Cavasinni, V.; Ceradini, F.; Cerda Alberich, L.; Cerio, B. C.; Cerqueira, A. S.; Cerri, A.; Cerrito, L.; Cerutti, F.; Cerv, M.; Cervelli, A.; Cetin, S. A.; Chafaq, A.; Chakraborty, D.; Chalupkova, I.; Chan, S. K.; Chan, Y. L.; Chang, P.; Chapman, J. D.; Charlton, D. G.; Chatterjee, A.; Chau, C. C.; Chavez Barajas, C. A.; Che, S.; Cheatham, S.; Chegwidden, A.; Chekanov, S.; Chekulaev, S. V.; Chelkov, G. A.; Chelstowska, M. A.; Chen, C.; Chen, H.; Chen, K.; Chen, S.; Chen, S.; Chen, X.; Chen, Y.; Cheng, H. C.; Cheng, H. J.; Cheng, Y.; Cheplakov, A.; Cheremushkina, E.; Cherkaoui El Moursli, R.; Chernyatin, V.; Cheu, E.; Chevalier, L.; Chiarella, V.; Chiarelli, G.; Chiodini, G.; Chisholm, A. S.; Chitan, A.; Chizhov, M. V.; Choi, K.; Chomont, A. R.; Chouridou, S.; Chow, B. K. B.; Christodoulou, V.; Chromek-Burckhart, D.; Chudoba, J.; Chuinard, A. J.; Chwastowski, J. J.; Chytka, L.; Ciapetti, G.; Ciftci, A. K.; Cinca, D.; Cindro, V.; Cioara, I. A.; Ciocio, A.; Cirotto, F.; Citron, Z. H.; Ciubancan, M.; Clark, A.; Clark, B. L.; Clark, M. R.; Clark, P. J.; Clarke, R. N.; Clement, C.; Coadou, Y.; Cobal, M.; Coccaro, A.; Cochran, J.; Coffey, L.; Colasurdo, L.; Cole, B.; Cole, S.; Colijn, A. P.; Collot, J.; Colombo, T.; Compostella, G.; Conde Muiño, P.; Coniavitis, E.; Connell, S. H.; Connelly, I. A.; Consorti, V.; Constantinescu, S.; Conta, C.; Conti, G.; Conventi, F.; Cooke, M.; Cooper, B. D.; Cooper-Sarkar, A. M.; Cornelissen, T.; Corradi, M.; Corriveau, F.; Corso-Radu, A.; Cortes-Gonzalez, A.; Cortiana, G.; Costa, G.; Costa, M. J.; Costanzo, D.; Cottin, G.; Cowan, G.; Cox, B. E.; Cranmer, K.; Crawley, S. J.; Cree, G.; Crépé-Renaudin, S.; Crescioli, F.; Cribbs, W. 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M.; Xella, S.; Xu, D.; Xu, L.; Yabsley, B.; Yacoob, S.; Yakabe, R.; Yamaguchi, D.; Yamaguchi, Y.; Yamamoto, A.; Yamamoto, S.; Yamanaka, T.; Yamauchi, K.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, H.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yap, Y. C.; Yasu, Y.; Yatsenko, E.; Yau Wong, K. H.; Ye, J.; Ye, S.; Yeletskikh, I.; Yen, A. L.; Yildirim, E.; Yorita, K.; Yoshida, R.; Yoshihara, K.; Young, C.; Young, C. J. S.; Youssef, S.; Yu, D. R.; Yu, J.; Yu, J. M.; Yu, J.; Yuan, L.; Yuen, S. P. Y.; Yusuff, I.; Zabinski, B.; Zaidan, R.; Zaitsev, A. M.; Zakharchuk, N.; Zalieckas, J.; Zaman, A.; Zambito, S.; Zanello, L.; Zanzi, D.; Zeitnitz, C.; Zeman, M.; Zemla, A.; Zeng, J. C.; Zeng, Q.; Zengel, K.; Zenin, O.; Ženiš, T.; Zerwas, D.; Zhang, D.; Zhang, F.; Zhang, G.; Zhang, H.; Zhang, J.; Zhang, L.; Zhang, R.; Zhang, R.; Zhang, X.; Zhang, Z.; Zhao, X.; Zhao, Y.; Zhao, Z.; Zhemchugov, A.; Zhong, J.; Zhou, B.; Zhou, C.; Zhou, L.; Zhou, L.; Zhou, M.; Zhou, N.; Zhu, C. G.; Zhu, H.; Zhu, J.; Zhu, Y.; Zhuang, X.; Zhukov, K.; Zibell, A.; Zieminska, D.; Zimine, N. I.; Zimmermann, C.; Zimmermann, S.; Zinonos, Z.; Zinser, M.; Ziolkowski, M.; Živković, L.; Zobernig, G.; Zoccoli, A.; zur Nedden, M.; Zurzolo, G.; Zwalinski, L.

    2016-05-01

    This paper discusses various observations on beam-induced and cosmic-ray backgrounds in the ATLAS detector during the LHC 2012 proton-proton run. Building on published results based on 2011 data, the correlations between background and residual pressure of the beam vacuum are revisited. Ghost charge evolution over 2012 and its role for backgrounds are evaluated. New methods to monitor ghost charge with beam-gas rates are presented and observations of LHC abort gap population by ghost charge are discussed in detail. Fake jets from colliding bunches and from ghost charge are analysed with improved methods, showing that ghost charge in individual radio-frequency buckets of the LHC can be resolved. Some results of two short periods of dedicated cosmic-ray background data-taking are shown; in particular cosmic-ray muon induced fake jet rates are compared to Monte Carlo simulations and to the fake jet rates from beam background. A thorough analysis of a particular LHC fill, where abnormally high background was observed, is presented. Correlations between backgrounds and beam intensity losses in special fills with very high β* are studied.

  19. Impact of infection control activities on the rate of needle stick injuries at a tertiary care hospital of Pakistan over a period of six years: an observational study

    PubMed Central

    2009-01-01

    Background Accidental exposure to blood and body fluids is frequent among health care workers. They are at high risk of nosocomial transmission of blood borne pathogens due to injuries caused by used sharps. We are reporting impact of surveillance and educational program on the rate of needle stick injuries among health care workers at a tertiary care hospital in Pakistan. Methods At Aga Khan University Hospital sharp injuries are reported to infection control office. To reduce these incidents a quality improvement project was inducted in the year 2005. Health care workers were educated; surveillance data from 2002 to 2007 was analyzed and compared with various risk factors. Results During study period 1382 incidents were reported. Junior doctors sustained highest number of injuries (n = 394; 28.5%) followed by registered nurses (n = 283; 20.4%). Highest number of incidents was reported during blood collection (19%). An increasing trend was observed in the pre intervention years (2002–04). However noticeable fall was noted in the post intervention period that is in year 2006 and 2007. Major decline was noted among nurses (from 13 to 5 NSI/100 FTE/year). By relating and comparing the rates with various activities directly linked with the use of syringes a significant reduction in incidents were found including; hospital admissions (p-value 0.01), surgeries and procedures performed (p = 0.01), specimens collected in the laboratory (p = 0.001) and patients visits in clinics (p = 0.01). Conclusion We report significant reduction in needle stick injuries especially during post intervention study period. This is being achieved by constant emphasis on improving awareness by regular educational sessions, implemented as a quality improvement project. PMID:19480683

  20. Himematsutake (Iwade Strain 101) extract (ABM-FD): genetic toxicology and a 3-month dietary toxicity study in rats.

    PubMed

    Sumiya, T; Ikeda, Y; Broadmeadow, A; May, K; Pritchard, L; Horne, C; Burlinson, B

    2008-06-01

    Agaricus blazei Murrill, an edible mushroom, is used as a functional food due to medicinal effects of (1-->6)-beta-D-glucan protein complex which has been shown to have anti tumour activity in mice. A 13week oral subchronic study in rats performed at 500, 1000 or 2000mg/kg/day caused, at the highest dose, reduced erythrocyte numbers and high mean cell volume in males, high creatinine and urea concentrations in both sexes and low spleen weights in females, but no histopathological change. The findings suggested low level chronic toxicity at 2000mg/kg/day and a no observed adverse effect level (NOAEL) of 1000mg/kg/day. Genotoxicity tests on the aqueous extract were negative in the bacterial reverse mutation test, either with or without S9 mix, up to 5000microg/plate and in a rat bone marrow micronucleus test up to 2g/kg bodyweight. The extract was positive at acceptable levels of toxicity in an L5178Y mouse lymphoma assay following 24h exposure in the absence of S9 and this was associated with an increase in the number of small colonies, suggesting possible clastogenic activity or aneuploidy, rather than point mutation. The aqueous extract of A. blazei is therefore of low subchronic toxicity and did not cause any direct effect upon the DNA molecule and the weak positive in the L5178 mouse lymphoma test was likely due to large deletions or the loss of the whole chromosomes rather than to direct damage to the DNA.

  1. F3 layer development during quiet and disturbed periods as observed at conjugate locations in Brazil: The role of the meridional wind

    NASA Astrophysics Data System (ADS)

    Batista, Inez S.; Candido, C. M. N.; Souza, J. R.; Abdu, M. A.; Araujo, R. C.; Resende, L. C. A.; Santos, A. M.

    2017-02-01

    In this work we use ionospheric data from two low-latitude stations located north and south of the geomagnetic equator, at approximately the same magnetic longitude, in order to study the occurrence of the F3 layer. The location of the stations being at almost geomagnetically conjugate points is such that the effects of the electric field/vertical plasma drift and diffusion will be almost symmetric around the magnetic equator. Under this configuration it is possible to deduce the effect of meridional wind in the F3 layer occurrence. Our results show that during the December solstice the layer will be present at the Southern Hemisphere (SH) location in 97% of the days and in the Northern Hemisphere (NH) location in only 4% of the days. In the June solstice the situation is reversed with the occurrence in the NH being 82% and 16% in the SH. For the March equinox the occurrence is low at both locations (4% in NH and 7% in SH), being mainly present during magnetically disturbed periods. The analysis of the effective meridional wind based on the Horizontal Wind Model and on the asymmetry of the F layer peak height observed at the two locations confirms the ubiquitous role of the wind in the F3 layer formation and/or persistence during both quiet and disturbed periods. The B0 parameter, that is a measure of the thickness of the bottomside F region profile, revealed to be a good proxy for the F3 layer occurrence.

  2. Twenty-Four-Hour Raman Lidar Water Vapor Measurements During the Atmospheric Radiation Measurement Program's 1996 and 1997 Water Vapor Intensive Observation Periods

    SciTech Connect

    Turner, David D.; Goldsmith, JE M.

    1999-08-01

    Prior to the Atmospheric Radiation Measurement program's first water vapor intensive observation period (WVIOP) at the Cloud and Radiation Testbed site near Lamont, Oklahoma, an automated 24-h Raman lidar was delivered to the site. This instrument, which makes high-resolution measurements of water vapor both spatially and temporally, is capable of making these measurements with no operator interaction (other than initial startup) for days at a time. Water vapor measurements collected during the 1996 and 1997 WVIOPs are discussed here, illustrating both the nighttime and daytime capabilities of this system. System characteristics, calibration issues, and techniques are presented. Finally, detailed intercomparisons of the lidar's data with those from a microwave radiometer, radiosondes, an instrumented tower, a chilled mirror flown on both a tethersonde and a kite, and measurements from aircraft are shown and discussed, highlighting the accuracy and stability of this system for both nighttime and daytime measurements.

  3. A synoptic-scale overview of the TOGA COARE intensive observing period November 1992 to February 1993 based on analyses from US operational global data assimilation systems

    NASA Technical Reports Server (NTRS)

    Fiorino, M.; Lord, S. J.; Lau, W. K.-M.; Phoebus, P. A.; Strey, C. G.

    1993-01-01

    The operational global analyses from the two major U.S. numerical weather prediction centers, the Navy's Fleet Numerical Oceanography Center and the National Meteorological Center, are used to describe the synoptic-scale features of the 1 Nov. 1992 to 28 Feb. 1993 TOGA COARE intensive observing period (IOP). TOGA COARE is an international field experiment in which a large number of research scientists from the Goddard Laboratory for Atmospheres (Code 910) and the Laboratory for Hydrospheres (Code 970) participated. Two high-amplitude intraseasonal (30-60 day) oscillations passed through the TOGA COARE observational network located in the equatorial western Pacific. Associated with the oscillations were two 6-10 day periods of persistent westerly surface winds at the equator or 'westerly wind bursts.' These events are depicted through time series and time-longitude cross sections of divergence/velocity potential, surface winds, precipitation, ocean mixed-layer depth, and sea surface temperature. The high and low frequency components of the flow in which the intraseasonal oscillations were embedded are shown using seasonal, monthly, and 5-day averages of the surface, 850 and 200 mb winds, precipitation, and sea-level pressure, and a time-longitude cross section of tropical cyclone activity. Independent verification of precipitation comes from near real-time satellite estimates, and a reference climatology is given based on 9 years of ECMWF analyses. Daily 00 UTC analyses of surface winds and sea-level pressure for the entire western Pacific and Indian Ocean are provided to trace the evolution of individual synoptic events.

  4. Improvement of the Management of Infants, Children and Adults with a Molecular Diagnosis of Enterovirus Meningitis during Two Observational Study Periods

    PubMed Central

    Archimbaud, Christine; Ouchchane, Lemlih; Mirand, Audrey; Chambon, Martine; Demeocq, François; Labbé, André; Laurichesse, Henri; Schmidt, Jeannot; Clavelou, Pierre; Aumaître, Olivier; Regagnon, Christel; Bailly, Jean-Luc; Henquell, Cécile; Peigue-Lafeuille, Hélène

    2013-01-01

    Enteroviruses (EVs) are a major cause of aseptic meningitis, and RNA detection using molecular assay is the gold standard diagnostic test. The aim of this study was to assess the impact of an EV positive diagnosis on the clinical management of patients admitted for meningitis over the course of two observational study periods (2005 and 2008–09) in the same clinical departments. We further investigated in multivariate analysis various factors possibly associated with hospital length of stay (LOS) in all age groups (infants, children, and adults). The results showed an overall improvement in the management of patients (n = 142) between the study periods, resulting in a significantly shorter hospital LOS for adults and children, and a shorter duration of antibiotic use for adults and infants. In multivariate analysis, we observed that the time from molecular test results to discharge of patients and the median duration of antibiotic treatment were associated with an increase in LOS in all age groups. In addition, among adults, the turnaround time of the molecular assay was significantly correlated with LOS. The use of CT scan in children and hospital admission outside the peak of EV prevalence in infants tended to increase LOS. In conclusion, the shorter length of stay of patients with meningitis in this study was due to various factors including the rapidity of the EV molecular test (particularly in adults), greater physician responsiveness after a positive result (in adults and children), and greater experience on the part of physicians in handling EV meningitis, as evidenced by the shorter duration of antibiotic use in adults and infants. PMID:23874676

  5. Explorer 45 /S3-A/ observations of the magnetosphere and magnetopause during the August 4-6, 1972, magnetic storm period

    NASA Technical Reports Server (NTRS)

    Hoffman, R. A.; Maynard, N. C.; Smith, P. H.; Cahill, L. J., Jr.; Anderson, R. R.; Gurnett, D. A.; Fritz, T. A.; Williams, D. J.; Konradi, A.

    1975-01-01

    The Explorer 45 (S3-A) satellite performed extensive field and particle measurements in the heart of the magnetosphere during the double magnetic storm period of August 4-6, 1972. Both the ground level magnetic records and the magnetic field deformations measured along the orbit by the satellite indicated the existence of only a moderate ring current. This was confirmed by the measurements of the total proton energy density by the on-board particle detectors, which showed a maximum energy density less than the densities observed during the December 1971 and June 1972 magnetic storms. The plasmapause in the noon quadrant was eroded continuously from the onset of the first storm at the beginning of August 4 to an altitude below L = 2.07 at about 1800 hours on August 5. Throughout the entire orbit during which the second sudden commencement occurred, a large amount of low-frequency electric and magnetic field noise was encountered. The most remarkable observation during this orbit was the contraction of the magnetopause to distances inside the satellite location at L = 5.2.

  6. Cloud Properties Derived From GOES-7 for Spring 1994 ARM Intensive Observing Period Using Version 1.0.0 of ARM Satellite Data Analysis Program

    NASA Technical Reports Server (NTRS)

    Minnis, Patrick; Smith, William L., Jr.; Garber, Donald P.; Ayers, J. Kirk; Doelling, David R.

    1995-01-01

    This document describes the initial formulation (Version 1.0.0) of the Atmospheric Radiation Measurement (ARM) program satellite data analysis procedures. Techniques are presented for calibrating geostationary satellite data with Sun synchronous satellite radiances and for converting narrowband radiances to top-of-the-atmosphere fluxes and albedos. A methodology is documented for combining geostationary visible and infrared radiances with surface-based temperature observations to derive cloud amount, optical depth, height, thickness, temperature, and albedo. The analysis is limited to two grids centered over the ARM Southern Great Plains central facility in north-central Oklahoma. Daytime data taken during 5 Apr. - 1 May 1994, were analyzed on the 0.3 deg and 0.5 deg latitude-longitude grids that cover areas of 0.9 deg x 0.9 deg and 10 deg x 14 deg, respectively. Conditions ranging from scattered low cumulus to thin cirrus and thick cumulonimbus occurred during the study period. Detailed comparisons with hourly surface observations indicate that the mean cloudiness is within a few percent of the surface-derived sky cover. Formats of the results are also provided. The data can be accessed through the World Wide Web computer network.

  7. What Are the Trends in Tonsillectomy Techniques in Wales? A Prospective Observational Study of 19,195 Tonsillectomies over a 10-Year Period

    PubMed Central

    Walijee, Hussein; Al-Hussaini, Ali; Harris, Andrew; Owens, David

    2015-01-01

    There are a multitude of techniques to undertake tonsillectomy, with hot techniques such as diathermy and coblation being associated with a higher risk of secondary haemorrhage. The UK National Prospective Tonsillectomy Audit (2004) advocated cold steel dissection and ties to be the gold standard. This prospective observational study investigates the trends in tonsillectomy techniques across Wales in the last decade to establish if surgeons have adhered to this national guidance. Data relating to tonsillectomy were extracted over a 10-year period from 1 January 2003 to 31 December 2012 from the Wales Surgical Instrument Surveillance Programme database. A total of 19,195 patients were included. Time-series analysis using linear regression showed there was an increase in the number of bipolar diathermy tonsillectomies by 84% (Pearson's r = 0.762, p = 0.010) and coblation tonsillectomies by 120% (r = 0.825, p = 0.003). In contrast, there was a fall in the number of cold steel dissection tonsillectomies with ties by 60% (r = −0.939, p < 0.001). This observational study suggests that the use of bipolar and coblation techniques for tonsillectomy has increased. This deviation from national guidance may be due to these techniques being faster with less intraoperative bleeding. Further study for the underlying reasons for the increase in these techniques is warranted. PMID:26693228

  8. A new high-resolution BOLAM-MOLOCH suite for the SIMM forecasting system: assessment over two HyMeX intense observation periods

    NASA Astrophysics Data System (ADS)

    Mariani, S.; Casaioli, M.; Coraci, E.; Malguzzi, P.

    2015-01-01

    High-resolution numerical models can be effective in monitoring and predicting natural hazards, especially when dealing with Mediterranean atmospheric and marine intense/severe events characterised by a wide range of interacting scales. The understanding of the key factors associated to these Mediterranean phenomena, and the usefulness of adopting high-resolution numerical models in their simulation, are among the aims of the international initiative HyMeX - HYdrological cycle in Mediterranean EXperiment. At the turn of 2013, two monitoring campaigns (SOPs - Special Observation Periods) were devoted to these issues. For this purpose, a new high-resolution BOlogna Limited Area Model-MOdello LOCale (BOLAM-MOLOCH) suite was implemented in the Institute for Environmental Protection and Research (ISPRA) hydro-meteo-marine forecasting system (SIMM - Sistema Idro-Meteo-Mare) as a possible alternative to the operational meteorological component based on the BOLAM model self-nested over two lower-resolution domains. The present paper provides an assessment of this new configuration of SIMM with respect to the operational one that was also used during the two SOPs. More in details, it investigates the forecast performance of these SIMM configurations during two of the Intense Observation Periods (IOPs) declared in the first SOP campaign. These IOPs were characterised by high precipitations and very intense and exceptional high waters over the northern Adriatic Sea (acqua alta). Concerning the meteorological component, the high-resolution BOLAM-MOLOCH forecasts are compared against the lower-resolution BOLAM forecasts over three areas - mostly corresponding to the Italian HyMeX hydrometeorological sites - using the rainfall observations collected in the HyMeX database. Three-month categorical scores are also calculated for the MOLOCH model. Despite the presence of a slight positive bias of the MOLOCH model, the results show that the precipitation forecast turns out to improve

  9. Simultaneous Polar and Cluster Observations of the High-Latitude Dayside Boundary Layer and Cusp During a Period of Enhanced Solar Wind Pressure

    NASA Astrophysics Data System (ADS)

    Coombs, J.; Fritz, T.; Zong, Q.

    2002-05-01

    indent 12pt On April 21, 2001, a sharp increase in both the density and velocity of the solar wind was recorded by the ACE spacecraft at approximately 15:00 U.T. This high density and enhanced velocity encountered the magnetosphere at 16:00 U.T. and persisted until 02:00 U.T. on April 22, 2001. Coupled with the velocity increase (Δ v ≈ 50 km/s), the density increase (Δ n ≈ 30 /cm3) created a large increase in the solar wind pressure that compressed the magnetopause boundary to within 8 Re. During this time period, both the Cluster and Polar spacecrafts were in close proximity of each other in the dayside high-latitude region of the magnetosphere. Cluster entered the northern cusp region from the night side and recorded an increase in the flux of energetic electrons and ions until it appeared to cross the compressed magnetopause boundary and enter the magnetosheath. During the compression, Polar was near apogee on the noon side, moving toward the night side where the MICS instrument recorded an increase in the flux of solar wind particles, He++ and O>+2, while recording an absence of particles of magnetospheric origin, He+ and O<+2. Having Cluster enter the cusp region while traveling outbound while Polar is at apogee near the magnetopause boundary on the noon side created a unique situation for understanding the size and dynamics of the cusp region as well as the positions of magnetospheric boundaries during a period of high solar wind pressure. These observations are compared to the prediction of the position of the magnetopause using a model by S. Petrinic (personal communication) and that of Tsyganenko 1996. Acknowledgement is given to both the Polar/CAMMICE and Cluster/Rapid teams.

  10. Minimum Acceptable Diet at 9 Months but Not Exclusive Breastfeeding at 3 Months or Timely Complementary Feeding Initiation Is Predictive of Infant Growth in Rural Bangladesh

    PubMed Central

    Owais, Aatekah; Schwartz, Benjamin; Kleinbaum, David G.; Suchdev, Parminder S.; Faruque, A. S. G.; Das, Sumon K.; Stein, Aryeh D.

    2016-01-01

    The association between suboptimal infant feeding practices and growth faltering is well-established. However, most of this evidence comes from cross-sectional studies. To prospectively assess the association between suboptimal infant feeding practices and growth faltering, we interviewed pregnant women at 28–32 weeks’ gestation and followed-up their offspring at postnatal months 3, 9, 16 and 24 months in rural Bangladesh. Using maternal recall over the past 24 hours, exclusive breastfeeding (EBF) status at 3 months, age at complementary feeding (CF) initiation, and receipt of minimum acceptable diet (MAD; as defined by WHO) at 9 months were assessed. Infant length and weight measurements were used to produce length-for-age (LAZ) and weight-for-length (WLZ) z-scores at each follow-up. Generalized estimating equations were used to estimate associations of LAZ and WLZ with infant feeding practices. All models were adjusted for baseline SES, infant sex, maternal height, age, literacy and parity. Follow-up was completed by 2189, 2074, 1969 and 1885 mother-child dyads at 3, 9, 16 and 24 months, respectively. Stunting prevalence increased from 28% to 57% between infant age 3 and 24 months. EBF at 3 months and age at CF initiation were not associated with linear infant growth, but receipt of MAD at 9 months was. By age 24 months, infants receiving MAD had attained a higher LAZ compared to infants who did not receive MAD (adjusted β = 0.25, 95% CI: 0.13–0.37). Although prevalence of stunting was already high at age 3 months, ensuring infants receive a diverse, high quality diet from 6 months onwards may reduce rates of stunting in the second year of life. PMID:27776161

  11. 3-Month experience in presbyopic correction with bi-aspheric multifocal central presbyLASIK treatments for hyperopia and myopia with or without astigmatism

    PubMed Central

    Luger, Michiel H.A.; Ewering, Tobias; Arba-Mosquera, Samuel

    2012-01-01

    Purpose To analyze simultaneous vision (distance and near) 3-month after bi-aspheric multifocal central presbyLASIK treatments for hyperopia and myopia with or without astigmatism. Methods Retrospective study analyzing patients that had been treated for correcting distance ametropiae and alleviating presbyopic symptoms simultaneously. All patients had been treated in Presby Aspheric mode using FemtoLASIK. No eye had previous corneal refractive surgery. Preoperative corneal curvature ranged between 40 D and 48 D, with pachymetry thicker than 500 μm. Preoperative best distance corrected visual acuity (CDVA) was 0.1 LogMAR or better, with best corrected near vision (CNVA) of 0.2 LogRAD or better. Results 66 patients treated using PresbyMAX software (SCHWIND eye-tech-solutions GmbH and Co. KG, Kleinostheim, Germany) were reviewed. For 24 patients, 3-month follow-up was completed. At 3 months, 71% of patients achieved UDVA 0.1 LogMAR or better, 79% patients obtained UNVA 0.1 LogRAD or better, and 83% of eyes were within 0.75 diopters (D) of defocus. Postoperative mean spherical equivalent refraction was −0.15 ± 0.50 D. Stability was achieved from the 6-week follow-up. 92% of patients achieved UDVA 0.2 LogMAR or better and UNVA 0.2 LogRAD or better. No statistical differences between myopes/hyperopes or between males/females were found. Conclusions Patient selection and expectation management are essential to achieve patient satisfaction. Even though optically the results are quite predictable, some patients find it difficult to adapt to the compromise between far and near vision, and others are dissatisfied by the minor loss of distance VA.

  12. Multiwavelength optical observations of chromospherically active binary systems. V. FF UMa (2RE J0933+624): a system with orbital period variation

    NASA Astrophysics Data System (ADS)

    Gálvez, M. C.; Montes, D.; Fernández-Figueroa, M. J.; de Castro, E.; Cornide, M.

    2007-09-01

    Context: This is the fifth paper in a series aimed at studying the chromospheres of active binary systems using several optical spectroscopic indicators to obtain or improve orbital solution and fundamental stellar parameters. Aims: We present here the study of FF UMa (2RE J0933+624), a recently discovered, X-ray/EUV selected, active binary with strong Hα emission. The objectives of this work are, to find orbital solutions and define stellar parameters from precise radial velocities and carry out an extensive study of the optical indicators of chromospheric activity. Methods: We obtained high resolution echelle spectroscopic observations during five observing runs from 1998 to 2004. We found radial velocities by cross correlation with radial velocity standard stars to achieve the best orbital solution. We also measured rotational velocity by cross-correlation techniques and have studied the kinematic by galactic space-velocity components (U, V, W) and Eggen criteria. Finally, we have determined the chromospheric contribution in optical spectroscopic indicators, from Ca ii H & K to Ca ii IRT lines, using the spectral subtraction technique. Results: We have found that this system presents an orbital period variation, higher than previously detected in other RS CVn systems. We determined an improved orbital solution, finding a circular orbit with a period of 3.274 days. We derived the stellar parameters, confirming the subgiant nature of the primary component (MP = 1.67 M⊙ and R sin{i}_P=2.17 R⊙) and obtained rotational velocities (v sin{i}), of 33.57 ± 0.45 km s-1 and 32.38 ± 0.75 km s-1 for the primary and secondary components respectively. From our kinematic study, we can deduce its membership to the Castor moving group. Finally, the activity study has given us a better understanding of the possible mechanisms that produce the orbital period variation. Based on observations collected with the 2.2 m telescope at the Centro Astronómico Hispano Alemán (CAHA

  13. Pulmonary haemosiderosis in a 13-year-old girl with coeliac disease after 3 months on a gluten-free diet: case report and review of the literature.

    PubMed

    Najada, A S; Dahabreh, M M

    2010-01-01

    A 13-year-old girl with controlled coeliac disease who had been on a gluten-free diet for the past 3 months was admitted with respiratory distress and hypoxia for the past week. Chest radiograph and CT scan showed bilateral widespread alveolar shadowing suggestive of a hypersensitive pneumonitis. There was a dramatic radiological and clinical response to oral corticosteroids. Bronchial lavage was suggestive of recurrent aspiration and histology of a transbronchial biopsy showed pulmonary haemosiderosis. We conclude that pulmonary haemosiderosis may occur in children with coeliac disease who are on a gluten-free diet.

  14. Antipsychotic prescribing in care homes before and after launch of a national dementia strategy: an observational study in English institutions over a 4-year period

    PubMed Central

    Szczepura, Ala; Owen, David W; Palmer, Thomas; Muhammad, Tariq; Clark, Michael D

    2016-01-01

    Objectives To assess associations between the launch of the National Dementia Strategy (NDS) and antipsychotic prescribing in long-term residential care (LTC) in England. Setting and participants Retrospective analysis of prescribing patterns in 616 LTC institutions (31 619 residents) following launch of the NDS, using information from electronic medicines management system. Primary and secondary outcome measures Antipsychotic prescribing point prevalence (PP) for all residents in a cross section of LTC settings over a 4-year period following NDS launch. Secondary outcomes included dosages, length of treatment and use of recommended second-generation antipsychotics (SGAs) versus first-generation antipsychotics (FGAs). Associations between facility-level PP values and institutional characteristics, resident demographics were explored. Variations across geographical areas examined. Prescription net ingredient costs calculated. Results No statistically significant difference was observed in overall prescribing rates over the 4-year period (Kolmogorov-Smirnov (KS) test p=0.60), and there was no significant shift towards newer SGAs (KS test p=0.32). Dosages were above the maximum indicated in only 1.3% of cases, but duration of prescribing was excessive in 69.7% of cases. Care homes in the highest prescribing quintile were more likely to be located in a deprived area (rate ratio (Q5/Q1) RR=5.89, 95% CI 4.35 to 7.99), registered for dementia (RR=3.38, 95% CI 3.06 to 3.73) and those in the lowest quintile were more likely to be served by a single general practitioner (GP) practice (RR=0.48; 95% CI 0.37 to 0.63); p<0.001 all. A sixfold variation in PP levels was observed between geographical areas. The average annual expenditure on antipsychotics was £65.6 per person resident (2012 prices). Conclusions The NDS in England was not associated with reduced PP levels or the types of antipsychotic prescribing in care homes. Further research is needed to explore why. Clear

  15. Causes of the Regional Variability in Observed Sea Level, Sea Surface Temperature and Ocean Colour Over the Period 1993-2011

    NASA Astrophysics Data System (ADS)

    Meyssignac, B.; Piecuch, C. G.; Merchant, C. J.; Racault, M.-F.; Palanisamy, H.; MacIntosh, C.; Sathyendranath, S.; Brewin, R.

    2017-01-01

    We analyse the regional variability in observed sea surface height (SSH), sea surface temperature (SST) and ocean colour (OC) from the ESA Climate Change Initiative datasets over the period 1993-2011. The analysis focuses on the signature of the ocean large-scale climate fluctuations driven by the atmospheric forcing and do not address the mesoscale variability. We use the ECCO version 4 ocean reanalysis to unravel the role of ocean transport and surface buoyancy fluxes in the observed SSH, SST and OC variability. We show that the SSH regional variability is dominated by the steric effect (except at high latitude) and is mainly shaped by ocean heat transport divergences with some contributions from the surface heat fluxes forcing that can be significant regionally (confirming earlier results). This is in contrast with the SST regional variability, which is the result of the compensation of surface heat fluxes by ocean heat transport in the mixed layer and arises from small departures around this background balance. Bringing together the results of SSH and SST analyses, we show that SSH and SST bear some common variability. This is because both SSH and SST variability show significant contributions from the surface heat fluxes forcing. It is evidenced by the high correlation between SST and buoyancy-forced SSH almost everywhere in the ocean except at high latitude. OC, which is determined by phytoplankton biomass, is governed by the availability of light and nutrients that essentially depend on climate fluctuations. For this reason, OC shows significant correlation with SST and SSH. We show that the correlation with SST displays the same pattern as the correlation with SSH with a negative correlation in the tropics and subtropics and a positive correlation at high latitude. We discuss the reasons for this pattern.

  16. Causes of the Regional Variability in Observed Sea Level, Sea Surface Temperature and Ocean Colour Over the Period 1993-2011

    NASA Astrophysics Data System (ADS)

    Meyssignac, B.; Piecuch, C. G.; Merchant, C. J.; Racault, M.-F.; Palanisamy, H.; MacIntosh, C.; Sathyendranath, S.; Brewin, R.

    2016-09-01

    We analyse the regional variability in observed sea surface height (SSH), sea surface temperature (SST) and ocean colour (OC) from the ESA Climate Change Initiative datasets over the period 1993-2011. The analysis focuses on the signature of the ocean large-scale climate fluctuations driven by the atmospheric forcing and do not address the mesoscale variability. We use the ECCO version 4 ocean reanalysis to unravel the role of ocean transport and surface buoyancy fluxes in the observed SSH, SST and OC variability. We show that the SSH regional variability is dominated by the steric effect (except at high latitude) and is mainly shaped by ocean heat transport divergences with some contributions from the surface heat fluxes forcing that can be significant regionally (confirming earlier results). This is in contrast with the SST regional variability, which is the result of the compensation of surface heat fluxes by ocean heat transport in the mixed layer and arises from small departures around this background balance. Bringing together the results of SSH and SST analyses, we show that SSH and SST bear some common variability. This is because both SSH and SST variability show significant contributions from the surface heat fluxes forcing. It is evidenced by the high correlation between SST and buoyancy-forced SSH almost everywhere in the ocean except at high latitude. OC, which is determined by phytoplankton biomass, is governed by the availability of light and nutrients that essentially depend on climate fluctuations. For this reason, OC shows significant correlation with SST and SSH. We show that the correlation with SST displays the same pattern as the correlation with SSH with a negative correlation in the tropics and subtropics and a positive correlation at high latitude. We discuss the reasons for this pattern.

  17. Comparison of 37 months global net radiation flux derived from PICARD-BOS over the same period observations of CERES and ARGO

    NASA Astrophysics Data System (ADS)

    Zhu, Ping; Wild, Martin

    2016-04-01

    The absolute level of the global net radiation flux (NRF) is fixed at the level of [0.5-1.0] Wm-2 based on the ocean heat content measurements [1]. The space derived global NRF is at the same order of magnitude than the ocean [2]. Considering the atmosphere has a negligible effects on the global NRF determination, the surface global NRF is consistent with the values determined from space [3]. Instead of studying the absolute level of the global NRF, we focus on the interannual variation of global net radiation flux, which were derived from the PICARD-BOS experiment and its comparison with values over the same period but obtained from the NASA-CERES system and inferred from the ocean heat content survey by ARGO network. [1] Allan, Richard P., Chunlei Liu, Norman G. Loeb, Matthew D. Palmer, Malcolm Roberts, Doug Smith, and Pier-Luigi Vidale (2014), Changes in global net radiative imbalance 1985-2012, Geophysical Research Letters, 41 (no.15), 5588-5597. [2] Loeb, Norman G., John M. Lyman, Gregory C. Johnson, Richard P. Allan, David R. Doelling, Takmeng Wong, Brian J. Soden, and Graeme L. Stephens (2012), Observed changes in top-of-the-atmosphere radiation and upper-ocean heating consistent within uncertainty, Nature Geoscience, 5 (no.2), 110-113. [3] Wild, Martin, Doris Folini, Maria Z. Hakuba, Christoph Schar, Sonia I. Seneviratne, Seiji Kato, David Rutan, Christof Ammann, Eric F. Wood, and Gert Konig-Langlo (2015), the energy balance over land and oceans: an assessment based on direct observations and CMIP5 climate models, Climate Dynamics, 44 (no.11-12), 3393-3429.

  18. Observation and modelling of turbulent mixing in the Kuril and Aleutian Straits and impact of its 18.6-year period tidal cycle on ocean and climate

    NASA Astrophysics Data System (ADS)

    Yasuda, I.; Tanaka, Y.; Itoh, S.; Hasumi, H.; Komatsu, K.; Osafune, S.; Yagi, M.; Tanaka, T.; Kaneko, H.; Ikeya, T.; Konda, S.; Nishioka, J.; Nakatsuka, T.; Katsumata, K.; Tatebe, H.; Watanabe, Y.; Hiroe, Y.; Nakamura, T.

    2012-12-01

    Direct turbulent observations in the Kuril Straits and Aleutian Straits reveal that tide-induced strong vertical mixing corresponds to strong shear of combined diurnal tidal and/or mean currents and significantly modifies the water-mass and potential vorticity distribution. Bi-decadal variability synchronized with 18.6-year period moon-tidal cycle were found in various parts of the ocean and climate indices: water-mass variability in the subarctic North Pacific, especially near the strong diurnal tide regions as Kuril Straits and Aleutian Islands, and in long-term climate indices as Pacific Decadal Oscillation (PDO) and El-Nino and Southern Oscillation (ENSO) in proxy-reconstructed records. In low-frequency part of the PDO and SOI records, negative (positive)-PDO and positive (negative)-SOI tend to occur in the 4-6-th (10-12-th) year after the maximum diurnal tide, which is consistent with the climate model experiments with locally enhanced vertical mixing around Kuril Straits showing that tidal mixing and its variability could generate bi-decadal variability in ocean and climate. Ocean and climate model experiments with parameterized tidal mixing explain some of the water-mass modifications and bi-decadal variability of water-masses and climate.

  19. Summary of Sonic Boom Rise Times Observed During FAA Community Response Studies over a 6-Month Period in the Oklahoma City Area

    NASA Technical Reports Server (NTRS)

    Maglieri, Domenic J.; Sothcott, Victor E.

    1990-01-01

    The sonic boom signature data acquired from about 1225 supersonic flights, over a 6-month period in 1964 in the Oklahoma City area, was enhanced with the addition of data relating to rise times and total signature duration. These later parameters, not available at the time of publication of the original report on the Oklahoma City sonic boom exposures, are listed in tabular form along with overpressure, positive impulse, positive duration, and waveform category. Airplane operating information along with the surface weather observations are also included. Sonic boom rise times include readings to the 1/2, 3/4, and maximum overpressure values. Rise time relative probabilities for various lateral locations from the ground track of 0, 5, and 10 miles are presented along with the variation of rise times with flight altitude. The tabulated signature data, along with corresponding airplane operating conditions and surface and upper level atmospheric information, are also available on electronic files to provide it in the format for more efficient and effective utilization.

  20. Variability in moist static energy budget associated with the Madden-Julian Oscillation over the eastern Maritime Continent during CINDY2011/DYNAMO extended observing period

    NASA Astrophysics Data System (ADS)

    Yokoi, S.

    2015-12-01

    In this study, we examine variability in the moist static energy (MSE) budget over eastern Maritime Continent during the CINDY2011/DYNAMO extended observing period (from October 2011 through March 2012) associated with five convective disturbance events that can be recognized as the Madden-Julian oscillation (MJO). It reveals that the surface fluxes and radiative heating contribute to the maintenance of the amplitude of column-integrated MSE anomaly, and thus to the intensity of the MJO. The vertical and horizontal advection terms contribute to the phase progression and possibly eastward propagation of MJO. The contribution of the vertical advection is mainly due to lower-tropospheric decent after the precipitation and MSE maxima, presumably associated with rain re-evaporation, while that of the horizontal advection is due to so-called dry intrusion. We also argue impact of several assumptions used in recent idealized models of the MJO on the MSE budget. The assumptions we examined include (1) the column-integrated radiative heating anomaly is taken proportional to the column water vapor, and (2) the anomaly in vertical advection of MSE is taken proportional to that of dry static energy (in other words, the normalized gross moist stability is taken constant). We demonstrate that the assumption 1 tends to speed up the phase progression, while the assumption 2 tends to slow it down.

  1. Periodontal health status in patients treated with the Invisalign® system and fixed orthodontic appliances: A 3 months clinical and microbiological evaluation

    PubMed Central

    Levrini, Luca; Mangano, Alessandro; Montanari, Paola; Margherini, Silvia; Caprioglio, Alberto; Abbate, Gian Marco

    2015-01-01

    Objective: The aim of this prospective study was to compare the periodontal health and the microbiological changes via real-time polymerase chain reaction (PCR) in patients treated with fixed orthodontic appliances and Invisalign® system (Align Technology, Santa Clara, California). Materials and Methods: Seventy-seven patients were enrolled in this study and divided into three groups (Invisalign® group, fixed orthodontic appliances group and control group). Plaque index, probing depth, bleeding on probing were assessed. Total biofilm mass and periodontal pathogens were analyzed and detected via real-time PCR. All these data were analyzed at the T0 (beginning of the treatment) T1 (1-month) and T2 (3 months); and statistically compared using the Mann–Whitney test for independent groups. Results: After 1-month and after 3 months of treatment there was only one sample with periodontopathic anaerobes found in patient treated using fixed orthodontic appliances. The Invisalign® group showed better results in terms of periodontal health and total biofilm mass compared to the fixed orthodontic appliance group. A statistical significant difference (P < 0.05) at the T2 in the total biofilm mass was found between the two groups. Conclusion: Patients undergoing orthodontic treatment with the Invisalign® System show a superior periodontal health in the short-term when compared to patients in treatment with fixed orthodontic appliances. Invisalign® should be considered as a first treatment option in patients with risk of developing periodontal disease. PMID:26430371

  2. Pulmonary embolism and 3-month outcomes in 4036 patients with venous thromboembolism and chronic obstructive pulmonary disease: data from the RIETE registry

    PubMed Central

    2013-01-01

    Background Patients with chronic obstructive pulmonary disease (COPD) have a modified clinical presentation of venous thromboembolism (VTE) but also a worse prognosis than non-COPD patients with VTE. As it may induce therapeutic modifications, we evaluated the influence of the initial VTE presentation on the 3-month outcomes in COPD patients. Methods COPD patients included in the on-going world-wide RIETE Registry were studied. The rate of pulmonary embolism (PE), major bleeding and death during the first 3 months in COPD patients were compared according to their initial clinical presentation (acute PE or deep vein thrombosis (DVT)). Results Of the 4036 COPD patients included, 2452 (61%; 95% CI: 59.2-62.3) initially presented with PE. PE as the first VTE recurrence occurred in 116 patients, major bleeding in 101 patients and mortality in 443 patients (Fatal PE: first cause of death). Multivariate analysis confirmed that presenting with PE was associated with higher risk of VTE recurrence as PE (OR, 2.04; 95% CI: 1.11-3.72) and higher risk of fatal PE (OR, 7.77; 95% CI: 2.92-15.7). Conclusions COPD patients presenting with PE have an increased risk for PE recurrences and fatal PE compared with those presenting with DVT alone. More efficient therapy is needed in this subtype of patients. PMID:23865769

  3. Estimating Parallax Error Due to Orbital Motion for HST/WFC3 Spatial Scan Observations of 19 Long-period Classical Cepheids

    NASA Astrophysics Data System (ADS)

    Anderson, Richard I.; Casertano, Stefano; Riess, Adam G.

    2017-01-01

    We employ the Hubble Space Telescope's Wide Field Camera 3 (HST/WFC3) in spatial scanning mode to measure 30 - 40μas parallax of 19 classical Cepheids in the Milky Way with the aim of improving the calibration of the cosmic distance scale (Riess et al. 2014; Casertano et al. 2016). The measured parallaxes are an order of magnitude more precise than parallaxes from the first Gaia data release and thus furthermore provide important cross-checks for Gaia data processing.Here we present our work aimed at estimating the parallax error due to orbital motion caused by undetected companion stars (Anderson et al. 2016). We have secured more than 1600 high-precision radial velocity (RV) measurements of the 19 long-period (Ppuls > 9d) Cepheids in our sample using ground-based telescopes on both hemispheres to investigate the presence of spectroscopic companions. We model the RV variability together with orbital motion using a grid of input orbital periods, Porb. We determine upper limits on the (unsigned) projected parallax error induced by hypothetical companions using the orbital configuration upper limits determined by modeling RV data. We thus show that our HST/WFC3 parallax measurements are subject to an error of less than 2% in parallax (i.e., typically less than ±7μas) for 16 stars in the sample, and < 4% for two Cepheids with fewer RV observations. For YZ Carinae, however, we correct the previously published orbital solution and show that the astrometric model must take into account orbital motion to avoid significant (approx. ±100μas) parallax error.We have further investigated long-timescale (Porb > 10yr) orbital motion using literature data and RV templates based on our new data. We thus discover new evidence for RV signals due to long-term orbital motion for 4 Cepheids and critically assess putative evidence for spectroscopic binarity previously reported based on data of much lesser quality. We caution that astrometric measurements of binaries with Porb on

  4. Ground-based observations of Saturn's auroral ionosphere over three days: Trends in H3+ temperature, density and emission with Saturn local time and planetary period oscillation

    NASA Astrophysics Data System (ADS)

    O'Donoghue, James; Melin, Henrik; Stallard, Tom S.; Provan, G.; Moore, Luke; Badman, Sarah V.; Cowley, Stan W. H.; Baines, Kevin H.; Miller, Steve; Blake, James S. D.

    2016-01-01

    On 19-21 April 2013, the ground-based 10-m W.M. Keck II telescope was used to simultaneously measure H3+ emissions from four regions of Saturn's auroral ionosphere: (1) the northern noon region of the main auroral oval; (2) the northern midnight main oval; (3) the northern polar cap and (4) the southern noon main oval. The H3+ emission from these regions was captured in the form of high resolution spectral images as the planet rotated. The results herein contain twenty-three H3+ temperatures, column densities and total emissions located in the aforementioned regions - ninety-two data points in total, spread over timescales of both hours and days. Thermospheric temperatures in the spring-time northern main oval are found to be cooler than their autumn-time southern counterparts by tens of K, consistent with the hypothesis that the total thermospheric heating rate is inversely proportional to magnetic field strength. The main oval H3+ density and emission is lower at northern midnight than it is at noon, in agreement with a nearby peak in the electron influx in the post-dawn sector and a minimum flux at midnight. Finally, when arranging the northern main oval H3+ parameters as a function of the oscillation period seen in Saturn's magnetic field - the planetary period oscillation (PPO) phase - we see a large peak in H3+ density and emission at ∼115° northern phase, with a full-width at half-maximum (FWHM) of ∼44°. This seems to indicate that the influx of electrons associated with the PPO phase at 90° is responsible at least in part for the behavior of all H3+ parameters. A combination of the H3+ production and loss timescales and the ±10° uncertainty in the location of a given PPO phase are likely, at least in part, to be responsible for the observed peaks in H3+ density and emission occurring at a later time than the peak precipitation expected at 90° PPO phase.

  5. Seasonal variation of aerosol vertical distributions in the middle and lower troposphere in Beijing and surrounding area during haze periods based on CALIPSO observation

    NASA Astrophysics Data System (ADS)

    Liu, Qiong; Ma, Xiaojun; Jin, Hongchun; Chen, Yonghang; Yu, Yang; Zhang, Hua; Cai, Changjie; Wang, Yuhui; Li, Hao

    2014-11-01

    The data from CALIPSO (Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations) satellite was used to analyze the aerosol micro-physical properties over Beijing and surrounding area during haze periods from 2007 to 2008 in this paper. The results showed as follows. The values of TABC (total attenuated backscatter coefficient) for aerosols accounted for about 25% with varying altitudes. The aerosol scattering ability little changed from 0-4 km, showing that the aerosol layer evenly distribute. At different altitude ranges (0-1, 1-2, 2-3 and 3-4 km above ground level), values of TABC almost concentrate in the range of 2.5×10-3 -4.5×10-3 km-1.sr-1. In spring, summer and winter, aerosol scattering has the similar variation, with the maximum of TABC ranging from 3.5×10-3 km-1.sr-1 to 4.5×10-3 km-1.sr-1, while the maximum of TABC in autumn is from 1.5×10-3 km-1.sr-1 to 2.5×10-3 km-1.sr-1. Aerosol shape and size are characterized by VDR (volume depolarization ratio) and TACR (total attenuated color ratio). Aerosols with VDR greater than 10% were more than the ones with VDR less than 10% at the same altitude range. Notably, aerosols with smaller VDR (0-10%) appeared more frequently in autumn than those in the other three seasons. For each altitude range, aerosols with TACR ranging from 0-0.2 contributed much more than those with TACR ranging from 1.8-2.0. The size of aerosols in summer was the largest and that in autumn was the smallest in middle and lower troposphere.

  6. Implementation of an Aerosol-Cloud Microphysics-Radiation Coupling into the NASA Unified WRF: Simulation Results for the 6-7 August 2006 AMMA Special Observing Period

    NASA Technical Reports Server (NTRS)

    Shi, J. J.; Matsui, T.; Tao, W.-K.; Tan, Q.; Peters-Lidard, C.; Chin, M.; Pickering, K.; Guy, N.; Lang, S.; Kemp, E. M.

    2014-01-01

    Aerosols affect the Earth's radiation balance directly and cloud microphysical processes indirectly via the activation of cloud condensation and ice nuclei. These two effects have often been considered separately and independently, hence the need to assess their combined impact given the differing nature of their effects on convective clouds. To study both effects, an aerosol-microphysics-radiation coupling, including Goddard microphysics and radiation schemes, was implemented into the NASA Unified Weather Research and Forecasting model (NU-WRF). Fully coupled NU-WRF simulations were conducted for a mesoscale convective system (MCS) that passed through the Niamey, Niger area on 6-7 August 2006 during an African Monsoon Multidisciplinary Analysis (AMMA) special observing period. The results suggest that rainfall is reduced when aerosol indirect effects are included, regardless of the aerosol direct effect. Daily mean radiation heating profiles in the area traversed by the MCS showed the aerosol (mainly mineral dust) direct effect had the largest impact near cloud tops just above 200 hectopascals where short-wave heating increased by about 0.8 Kelvin per day; the weakest long-wave cooling was at around 250 hectopascals. It was also found that more condensation and ice nuclei as a result of higher aerosol/dust concentrations led to increased amounts of all cloud hydrometeors because of the microphysical indirect effect, and the radiation direct effect acts to reduce precipitating cloud particles (rain, snow and graupel) in the middle and lower cloud layers while increasing the non-precipitating particles (ice) in the cirrus anvil. However, when the aerosol direct effect was activated, regardless of the indirect effect, the onset of MCS precipitation was delayed about 2 hours, in conjunction with the delay in the activation of cloud condensation and ice nuclei. Overall, for this particular environment, model set-up and physics configuration, the effect of aerosol

  7. Aerosol properties associated with air masses arriving into the North East Atlantic during the 2008 Mace Head EUCAARI intensive observing period: an overview

    NASA Astrophysics Data System (ADS)

    Dall'Osto, M.; Ceburnis, D.; Martucci, G.; Bialek, J.; Dupuy, R.; Jennings, S. G.; Berresheim, H.; Wenger, J. C.; Sodeau, J. R.; Healy, R. M.; Facchini, M. C.; Rinaldi, M.; Giulianelli, L.; Finessi, E.; Worsnop, D.; O'Dowd, C. D.

    2009-12-01

    As part of the EUCAARI Intensive Observing Period, a 4-week campaign to measure aerosol physical, chemical and optical properties, atmospheric structure, and cloud microphysics was conducted from mid-May to mid-June 2008 at the Mace Head Atmospheric Research Station, located at the interface of Western Europe and the NE Atlantic and centered on the west Irish coastline. During the campaign, continental air masses comprising both young and aged continental plumes were encountered, along with polar, Arctic and tropical air masses. Polluted-continental aerosol concentrations were of the order of 3000 cm-3, while background marine air aerosol concentrations were between 400-600 cm-3. The highest marine air concentrations occurred in polar air masses in which a 15 nm nucleation mode, with concentration of 1100 cm-3, was observed and attributed to open ocean particle formation. Black carbon concentrations in polluted air were between 300-400 ng m-3, and in clean marine air were less than 50 ng m-3. Continental air submicron chemical composition (excluding refractory sea salt) was dominated by organic matter, closely followed by sulphate mass. Although the concentrations and size distribution spectral shape were almost identical for the young and aged continental cases, hygroscopic growth factors (GF) and cloud condensation nuclei (CCN) to total condensation nuclei (CN) concentration ratios were significantly less in the younger pollution plume, indicating a more oxidized organic component to the aged continental plume. The difference in chemical composition and hygroscopic growth factor appear to result in a 40-50% impact on aerosol scattering coefficients and Aerosol Optical Depth, despite almost identical aerosol microphysical properties in both cases, with the higher values been recorded for the more aged case. For the CCN/CN ratio, the highest ratios were seen in the more age plume. In marine air, sulphate mass dominated the sub-micron component, followed by water

  8. Aerosol properties associated with air masses arriving into the North East Atlantic during the 2008 Mace Head EUCAARI intensive observing period: an overview

    NASA Astrophysics Data System (ADS)

    Dall'Osto, M.; Ceburnis, D.; Martucci, G.; Bialek, J.; Dupuy, R.; Jennings, S. G.; Berresheim, H.; Wenger, J.; Healy, R.; Facchini, M. C.; Rinaldi, M.; Giulianelli, L.; Finessi, E.; Worsnop, D.; Ehn, M.; Mikkilä, J.; Kulmala, M.; O'Dowd, C. D.

    2010-09-01

    As part of the EUCAARI Intensive Observing Period, a 4-week campaign to measure aerosol physical, chemical and optical properties, atmospheric structure, and cloud microphysics was conducted from mid-May to mid-June, 2008 at the Mace Head Atmospheric Research Station, located at the interface of Western Europe and the N. E. Atlantic and centered on the west Irish coastline. During the campaign, continental air masses comprising both young and aged continental plumes were encountered, along with polar, Arctic and tropical air masses. Polluted-continental aerosol concentrations were of the order of 3000 cm-3, while background marine air aerosol concentrations were between 400-600 cm-3. The highest marine air concentrations occurred in polar air masses in which a 15 nm nucleation mode, with concentration of 1100 cm-3, was observed and attributed to open ocean particle formation. Continental air submicron chemical composition (excluding refractory sea salt) was dominated by organic matter, closely followed by sulphate mass. Although the concentrations and size distribution spectral shape were almost identical for the young and aged continental cases, hygroscopic growth factors (GF) and cloud condensation nuclei (CCN) to total condensation nuclei (CN) concentration ratios were significantly less in the younger pollution plume, indicating a more oxidized organic component to the aged continental plume. The difference in chemical composition and hygroscopic growth factor appear to result in a 40-50% impact on aerosol scattering coefficients and Aerosol Optical Depth, despite almost identical aerosol microphysical properties in both cases, with the higher values been recorded for the more aged case. For the CCN/CN ratio, the highest ratios were seen in the more age plume. In marine air, sulphate mass dominated the sub-micron component, followed by water soluble organic carbon, which, in turn, was dominated by methanesulphonic acid (MSA). Sulphate concentrations were

  9. Strategic Intelligence Observations from the Pre-Vietnam and Pre-9/11 Periods for the Intelligence Professional and the Policy-Maker

    DTIC Science & Technology

    2007-05-01

    intelligence context is vital to grasp the constraints on the decision makers in each period. Therefore, the first section describes the period using...if necessary. 1/2/63 A 3 battalion So. Vietnamese army pincer attack against a badly outnumbered Viet Cong unit near the southern village of Ap Bac

  10. Debridement with prosthesis retention and antibiotherapy vs. two-stage revision for periprosthetic knee infection within 3 months after arthroplasty: a case-control study.

    PubMed

    Lizaur-Utrilla, A; Gonzalez-Parreño, S; Gil-Guillen, V; Lopez-Prats, F A

    2015-09-01

    Sixty-four patients with periprosthetic infection within 3 months of index arthroplasty, of whom 39 underwent debridement with prosthesis retention and antibiotherapy (DPRA), and 25 underwent two-stage revision (2SR), were compared regarding control of infection and functional outcomes by use of Knee Society scores. Failure was defined as the need for subsequent surgery to control infection. The failure rate after DPRA was 61.5%, and that after 2SR was 12.0% (p 0.001). The failure risk was not significantly associated with the duration of symptoms (≤4 weeks). The only predictor of failure was isolation of Staphylococcus aureus or Staphylococcus epidermidis. Treatment with 2SR required fewer surgical operations, a shorter duration of hospitalization, and a shorter duration of treatment. All patients who required a second debridement ultimately underwent prosthesis removal. The functional outcome was significantly better for 2SR at the last follow-up.

  11. Bilateral Leg Replantation in a 3-Month-Old Baby After a Knee Level Crush Amputation-A 2-Year Follow-up.

    PubMed

    Bulic, Kresimir; Antabak, Anko; Dujmovic, Anto; Kisic, Hrvoje; Lorencin, Mia

    2017-03-01

    We present a case of a successful bilateral leg replantation in a 3-month-old baby after a knee-level crush amputation with the loss of both knee joints. The legs were replanted after 4 hours of warm and an additional 2.5 and 3.5 hours of cold ischemia time. Both legs show motor and sensory reinnervation, without additional procedures performed on the right leg, and after a nerve reconstruction with cadaveric allografts on the left leg. Both replanted legs exhibit excellent bony and soft tissue growth. Two years after the injury, the patient is progressing well with rehabilitation, with favourable odds of having knee reconstructions performed at a later age. This is the youngest patient reported to have had successful replantation of both legs.

  12. Dosing and Switching Strategies for Paliperidone Palmitate 3-Month Formulation in Patients with Schizophrenia Based on Population Pharmacokinetic Modeling and Simulation, and Clinical Trial Data.

    PubMed

    Magnusson, Mats O; Samtani, Mahesh N; Plan, Elodie L; Jonsson, E Niclas; Rossenu, Stefaan; Vermeulen, An; Russu, Alberto

    2017-04-01

    Paliperidone palmitate 3-month formulation (PP3M), a long-acting injectable atypical antipsychotic, was recently approved in the US and Europe for the treatment of schizophrenia in adult patients who have already been treated with paliperidone palmitate 1-month formulation (PP1M) for ≥4 months. This article reviews the pharmacokinetic rationale for the approved dosing regimens for PP3M, dosing windows, management of missed doses and treatment discontinuation, switching to other formulations, and dosing in special populations. Approved PP3M dosing regimens are based on the comparisons of simulations with predefined dosing regimens using paliperidone palmitate and oral paliperidone extended release (ER) population pharmacokinetic models (one-compartment model with two saturable absorption processes for PP3M; one-compartment model with parallel zero- and first-order absorption for PP1M; two-compartment model with sequential zero- and first-order absorption for ER) versus clinical trial data. Covariates were obtained by resampling subject covariates from the pharmacokinetics database for PP1M and PP3M. Simulation scenarios with varying doses and covariate values were generated. The population median and 90% prediction interval of the simulated concentration-time profiles were plotted for simulation outcomes evaluation. Simulations described in this paper provide (a) simulated plasma exposures for switching from PP1M to PP3M, (b) support for a once-every-3-months injection cycle, (c) information on dosing windows and managing missed doses of PP3M, (d) important guidance on PP3M dosing in special patient populations, and (e) key PP3M pharmacokinetic exposure metrics based on the population pharmacokinetic PP3M model. Population pharmacokinetics provided practical guidance to establish dosing regimens for PP3M.

  13. Spectral Index and Quasi-Periodic Oscillation Frequency Correlation in Black Hole Sources: Observational Evidence of Two Phases and Phase Transition in Black Holes

    NASA Technical Reports Server (NTRS)

    Titarchuk, Lev; Fiorito, Ralph

    2004-01-01

    Recent studies have shown that strong correlations are observed between the low frequencies (1-10 Hz) of quasi-periodic oscillations (QPOs) and the spectral power law index of several black hole (BH) candidate sources, in low (hard) states, steep power law (soft) states, and transitions between these states. The observations indicate that the X-ray spectra of such state (phases) show the presence of a power-law component and are sometimes related to simultaneous radio emission, indicating the probable presence of a jet. Strong QPOs (>20% rms) are present in the power density spectrum in the spectral range where the power-law component is dominant (i.e., 60%90%). This evidence contradicts the dominant, long-standing interpretation of QPOs as a signature of the thermal accretion disk. We present the data from the literature and our own data to illustrate the dominance of power-law index-QPO frequency correlations. We provide a model that identifies and explains the origin of the QPOs and how they are imprinted on the properties of the power-law flux component. We argue for the existence of a bounded compact coronal region that is a natural consequence of the adjustment of the Keplerian disk flow to the innermost sub-Keplerian boundary conditions near the central object and that ultimately leads to the formation of a transition layer (TL) between the adjustment radius and the innermost boundary. The model predicts two phases or states dictated by the photon upscattering produced in the TL: (1) a hard state, in which the TL is optically thin and very hot (kT approximately greater than 50 keV), producing photon upscattering via thermal Comptonization (the photon spectrum index Gamma approximates 1.7 for this state is dictated by gravitational energy release and Compton cooling in an optically thin shock near the adjustment radius), and (2) a soft state that is optically thick and relatively cold (kT approximately less than 5 keV the index for this state, Gamma

  14. Part 3. Assessment of genotoxicity and oxidative stress after exposure to diesel exhaust from U.S. 2007-compliant diesel engines: report on 1- and 3-month exposures in the ACES bioassay.

    PubMed

    Hallberg, L M; Ward, J B; Hernandez, C; Ameredes, B T; Wickliffe, J K

    2012-09-01

    -exposed animals. Results from the comet assay showed no significant differences in rats between the control and exposed groups (P = 0.53, low exposure; P = 0.92, medium exposure; P = 0.77, high exposure) after 1 month of DE exposure. There were no differences between sexes in the responses of rats to these exposures. Likewise, there were no significant differences found after 3 months of exposure. Similarly, no significant differences were found between the mice exposed for 1 and 3 months to DE, nor were any differences found between sexes. Measurements of 8-OHdG in both mice and rats showed no significant difference among DE exposure groups (P = 0.46, mice; P = 0.86, rats). In mice, measured 8-OHdG was lower in the 3-month group than the 1-month group. In rats, the inverse was true. In mice, no significant differences in the levels of lipid peroxidation, as measured by TBARS, were found between the controls and DE exposure groups (P = 0.92), nor were there any differences between sexes. In rats, comparisons between the control and low-exposure groups approached significance, but no significant differences were found between the other DE exposure groups. Additionally, in rats, there were no significant differences between the 1- and 3-month DE exposure groups.

  15. X-RAY, FUV, AND UV OBSERVATIONS OF {alpha} CENTAURI B: DETERMINATION OF LONG-TERM MAGNETIC ACTIVITY CYCLE AND ROTATION PERIOD

    SciTech Connect

    DeWarf, L. E.; Guinan, E. F.; Datin, K. M.

    2010-10-10

    Over the last couple of decades we have been carrying out a study of stellar magnetic activity, dynamos, atmospheric physics, and spectral irradiances from a sample of solar-type G0-5 V stars with different ages. One of the major goals of this program is to study the evolution of the Sun's X-ray through NUV spectral irradiances with age. Of particular interest is the determination of the young Sun's elevated levels of high-energy fluxes because of the critical roles that X-ray (coronal) through FUV (transition region (TR), chromospheric) emissions play on the photochemical and photoionization evolution (and possible erosion) of early, young planetary atmospheres and ionospheres. Motivated by the current exoplanetary search missions (such as Kepler and CoRoT, along with the planned Space Interferometry Mission and Darwin/Terrestrial Planet Finder missions) that are hunting for Earth-size planets in the habitable zones (liquid water) of nearby main-sequence G-M stars, we are expanding our program to cooler, less luminous, but very importantly, much more numerous main-sequence K-type stars, such as {alpha} Centauri B. The long life (2-3x longer than the Sun) and slow evolution of K stars provide nearly constant energy sources for possible hosted planets. This program parallels our 'Sun in Time' program, but extends the study to stars with deeper convective zone depths. Presented here are X-ray (coronal; ROSAT, Chandra, XMM-Newton), UV (TR; International Ultraviolet Explorer (IUE)), NUV (chromospheric; IUE), and recently acquired FUV (TR/chromospheric; FUSE Cycles 7/8) observations of the K1 V star {alpha} Cen B (HD 128621; V = 1.33; (B - V) = +0.88; {tau} = 5.6 {+-} 0.6 Gyr). These combined high-energy measures provide a more complete look into the nature of {alpha} Cen B's magnetic activity and X-ray-UV radiances. We find that {alpha} Cen B has exhibited significant long-term variability in X-ray through NUV emission fluxes, indicating a solar-like long-term activity

  16. Dynamics and evolution of tree populations and soil-vegetation relationships in Fogscapes: Observations over a period of 14 years at the experimental sites of Meija (Peru).

    NASA Astrophysics Data System (ADS)

    Salbitano, F.; Calamini, G.; Certini, G.; Ortega, A.; Pierguidi, A.; Villasante, L.; Caceres, R.; Coaguila, D.; Delgado, M.

    2010-07-01

    The Fogscapes, i.e. fog-dependent landscapes, and the sub mountain drylands of the Pacific Coast from Ecuador to Northern Chile are amongst the most fragile regions of the planet. The so-called "Lomas" (i.e. Hills) ecosystems are characterised by pre-desertic flora and vegetation where the plant phenological pattern coincides with the fog season from June to December every year. The occurance of ENSO (El Niño Southern Oscillation) affects these ecosystems inducing, occasionally, a sudden change in the characteristics of the vegetation. Relics of low-density woodlands dominated by Caesalpinea spinosa and scattered trees of the same species (which during the fog season appear as savannah-like ecosystems) are still present but becoming increasingly rare due to past and present overgrazing In the experimental site of Las Cuchillas, located on the coastal hills close to Meija (Dept. Arequipa, South Peru) trees of native species (Caesalpinaea spinosa and Prosopis pallida) and exotic species (Acacia saligna, Casuarina equisetifolia, Parkinsonia aculeata) were planted in 1996, in order to look at the rehabilitation potential of the degraded "lomas" ecosystems. This paper deals with the results observed over a period of 14 years’ of tree growth patterns and the related results concerning the soil and habitat dynamics. Among indigenous species Caesalpinea spinosa shows the heighest rate of survival even if the height increment is low and the tree crowns tend to dry out at a height of approximately two metres, followed by the appearance of new shoots produced during the course of the seasons. The exotic Acacia saligna shows the maximum height, diameter and crown volume increments. The habitat conditions, both in term of diversity / frequency of plant and animal populations, and plant cover (LAI estimated by processing fish-eye lens images) have changed substantially over the years. A number of samples from the top mineral soil and random samples from the forest floor were

  17. 46 CFR 189.27-5 - Periodic inspection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... periodic inspection within 3 months before or after the second or third anniversary of the date of your vessel's Certificate of Inspection. This periodic inspection will take the place of an annual inspection. (b) You must contact the cognizant OCMI to schedule an inspection at a time and place which he or...

  18. Vertical distribution of ambient aerosol extinctive properties during haze and haze-free periods based on the Micro-Pulse Lidar observation in Shanghai.

    PubMed

    Liu, Qiong; He, Qianshan; Fang, Sihua; Guang, Ying; Ma, Chengyu; Chen, Yonghang; Kang, Yanming; Pan, Hu; Zhang, Hua; Yao, Yifeng

    2017-01-01

    Ambient aerosols make a significant contribution to the environment and climate through their optical properties. In this study, the aerosol extinction coefficient and Aerosol optical depth (AOD) retrieved using the Fernald Method from the ground-based Micro-Pulse Lidar (MPL) were used to investigate the characteristics of aerosols during haze and haze-free periods in Shanghai. There were 216 haze days including 145 dry haze days, 39 damp haze days and 32days of both dry and damp haze in Shanghai from March 2009 to February 2010. During the haze periods, aerosols were concentrated mainly below 600m resulting in the most severe pollution layer in Shanghai. In contrast to the aerosol optical properties during haze-free periods, aerosol extinction coefficients and AOD were larger in the lower altitude (below 1km) during haze periods. The lowest 1km contributed 53-72% of the Aerosol optical depth (AOD) below 6km for the haze periods and <41% of that for the haze-free periods except summer. According to the analysis of influencing factors, although atmospheric convection was strong in summer which led to reduce the extinction, the highest occurrence of haze with relatively low aerosol extinction most of time was in summer, which resulted from the factors such as higher relative humidity, temperature and more solar radiation causing hygroscopic growth of particles and formation of secondary aerosols; in spring and autumn, there was less haze occurrences because the boundary layer was relatively higher, which allowed pollutants to diffuse more easily, but spring was the second most frequency season of haze due to frequent dust transport from the north; in winter high concentrations of particles and low boundary layer height were not beneficial to the diffusion of pollutants near the surface and caused haze occurrence rather high with high aerosol extinction.

  19. Part 2. Assessment of genotoxicity after exposure to diesel exhaust from U.S. 2007-compliant diesel engines: report on 1- and 3-month exposures in the ACES bioassay.

    PubMed

    Bemis, Jeffrey C; Torous, Dorothea K; Dertinger, Stephen D

    2012-09-01

    genotoxicity. Statistical approaches employed analysis of variance (ANOVA) to compare effects of sex, exposure condition, and duration, as well as their interactions. This initial assessment of MN was performed on both mouse and rat blood samples from the 1-month and 3-month exposures. The data from mice demonstrate the well established, sex-based difference in MN-RET and MN-NCE frequencies regularly observed in this species, with females exhibiting slightly lower frequencies. There were no sex-based differences observed in rats. An examination of the mean frequencies across the exposure groups and durations of exposure did not show an appreciable induction of MN at the 1- or 3-month exposures in either species. Further statistical analyses did not reveal any significant exposure-related effects. An examination of the potential genotoxic effects of DE is clearly valuable as part of a large-scale chronic-exposure bioassay. The data and observations from the 1-and 3-month exposure studies will eventually be combined with the results from the 1- and 2-year exposure studies to provide a comprehensive examination of chronic exposure to DE in a rodent model. This examination of chromosome damage serves an important role in the context of the entire ACES bioassay, which was designed to assess the safety of diesel combustion engines.

  20. Irregular Periods

    MedlinePlus

    ... number of days after the last one. The Menstrual Cycle Most girls get their first period between the ... to skip periods or to have an irregular menstrual cycle. Illness, rapid weight change, or stress can also ...

  1. Difference in production routes of water-soluble organic carbon in PM2.5 observed during non-biomass and biomass burning periods in Gwangju, Korea.

    PubMed

    Yu, Geun-Hye; Cho, Sung-Yong; Bae, Min-Suk; Park, Seung-Shik

    2014-07-01

    4 h integrated PM2.5 samples were collected from an urban site of Gwangju, Korea, for five days and analyzed for organic carbon and elemental carbon (OC and EC), total water-soluble OC (WSOC), hydrophilic and hydrophobic WSOC fractions (WSOCHPI and WSOCHPO), oxalate, and inorganic ionic species (sodium (Na(+)), ammonium (NH4(+)), potassium (K(+)), calcium (Ca(2+)), magnesium (Mg(2+)), chloride (Cl(-)), nitrate (NO3(-)), and sulfate (SO4(2-))) to investigate the possible sources of water-soluble organic aerosols. Two types of sampling periods were classified according to the regression relationship between black carbon (BC) concentrations measured at wavelengths of 370 nm (BC370nm) and 880 nm (BC880nm) using an aethalometer; the first period was traffic emission influence ("non-biomass burning (BB) period") and the second was biomass burning influence ("BB period"). The slope of the regression equation (BC370nm/BC880nm) was 0.95 for the non-BB period and 1.29 for the BB period. However, no noticeable difference in the WSOC/OC ratio, which can be used to infer the extent of secondary organic aerosol (SOA) formation, was found between the non-BB (0.61, range = 0.43-0.75) and BB (0.61, range = 0.52-0.68) periods, due to significant contribution of primary BB emissions to the WSOC. The concentrations of OC, WSOC and K(+), which were used as the BB emission markers, were 15.7 μg C m(-3) (11.5-24.3), 9.4 μg C m(-3) (7.0-12.7), and 1.2 μg m(-3) (0.6-2.7), respectively, during the BB period, and these results were approximately 1.7, 1.7, and 3.9 times higher than those during the non-BB period. During the non-BB period, good correlations among WSOC, SO4(2-) and oxalate, and poor correlations among WSOC, EC, and K(+) suggest that SOA is probably an important source of WSOC (and WSOCHPI) concentration. For the WSOC fractions, better correlations among WSOCHPI, oxalate (R(2) = 0.52), and SO4(2-) (R(2) = 0.57) were found than among WSOCHPO, oxalate (R(2) = 0.23), and SO4

  2. Raman lidar measurements of water vapor and aerosols during the atmospheric radiation measurement (ARM) remote clouds sensing (RCS) intensive observation period (IOP)

    SciTech Connect

    Melfi, S.H.; Starr, D.O`C.; Whiteman, D.

    1996-04-01

    The first Atmospheric Radiation Measurement (ARM) remote Cloud Study (RCS) Intensive Operations Period (IOP) was held during April 1994 at the Southern Great Plains (SGP) site. This experiment was conducted to evaluate and calibrate state-of-the-art, ground based remote sensing instruments and to use the data acquired by these instruments to validate retrieval algorithms developed under the ARM program.

  3. Prevalence and risk factors of posttraumatic stress disorder among teachers 3 months after the Lushan earthquake: A cross-sectional study.

    PubMed

    Zhang, Jun; Zhang, Ye; Du, Changhui; Zhu, Shenyue; Huang, Yalin; Tian, Yulian; Chen, Decao; Li, Haimin; Gong, Yao; Zhang, Mengmeng; Gu, Bo

    2016-07-01

    Teachers and students often suffer from the same disaster. The prevalence of PTSD in students has been given great attention. However, in acting as mentors to students and their families, teachers are more likely to have vicarious and indirect exposure via hearing stories of their aftermath and witnessing the consequences of traumatic events. There are limited data pertaining to the prevalence of PTSD and its risk factors among teachers. A total of 316 teachers from 21 primary and secondary schools in Baoxing County were administered a project-developed questionnaire which included the items regarding demographic characteristics, earthquake-related experiences, somatic discomforts, emotional reactions, support status, and everyday functioning 2 weeks after the Lushan earthquake, and they finished a 1-to-1 telephone interview for addressing the PTSD criteria of the Mini International Neuropsychiatric Interview (MINI) 3 months after the earthquake. The prevalence of PTSD was 24.4% among teachers. Somatic discomforts (odds ratio [OR] 1.89, 95% confidence interval [CI] 1.06-3.37) were positive risk factors of PTSD. Perceived social support (OR 0.30, 95% CI 0.14-0.62) and being able to calm down (OR 0.25, 95% CI 0.09-0.75) in teaching were negative risk factors. PTSD is commonly seen among teachers after an earthquake, and risk factors of PTSD were identified. These findings may help those providing psychological health programs to find the teachers who are at high risk of PTSD in schools after an earthquake in China.

  4. Effects of functional movement strength training on strength, muscle size, kinematics, and motor function in cerebral palsy: a 3-month follow-up.

    PubMed

    Lee, Jung Ah; You, Joshua H; Kim, Dong A; Lee, Min Jin; Hwang, Pil Woo; Lee, Nam Gi; Park, Jeong Joon; Lee, Dong Ryul; Kim, Hyun-Kyung

    2013-01-01

    We investigated the long-term effects of comprehensive hand repetitive intensive strengthening training (CHRIST) on strength, morphological muscle size, kinematics, and associated motor functional changes in children with cerebral palsy (CP). Ten children (5 boys, 5 girls; age range, 6-11 years, mean age, 8.6 years) participated in the study. The children were classified according to the Manual Ability Classification System: 5 were Level II, 2 were Level III, and 3 were Level IV. Quantitative biomechanical measurements were performed to determine muscle strength, muscle size, kinematics (normalized jerk score), and motor function using a dynamometer, ultrasound, Vicon motion analysis, and standardized clinical tests (Quality of Upper Extremity Skills Test, Jebsen-Taylor Hand Function Test, Functional Independence Measure, and Pediatric Motor Activity Log), respectively. Muscle strength, muscle size, kinematics, and motor function significantly improved after a 10-week intervention (3 times a week), and the long-term effects remained even at the 3-month follow-up. In conclusion, this is the first study highlighting the long-term efficacy of upper extremity strength training using the novel CHRIST system in children with CP, which will potentially open up new horizons for effective management in pediatric neurorehabilitation.

  5. Operation of a digital seismic network on Mount St. Helens volcano and observations of long-period seismic events that originate under the volcano

    SciTech Connect

    Fehler, M.; Chouet, B.

    1982-01-01

    During the period May through October 1981, a nine station digital seismic array was operated on the flanks of Mount St. Helens volcano in the state of Washington. The purpose was to obtain high quality digital seismic data from a dense seismic array operating near and in the summit crater of the volcano to facilitate study of near field seismic waveforms generated under the volcano. Our goal is to investigate the source mechanism of volcanic tremor and seismic activity associated with magma intrusion, dome growth and steam-ash emissions occurring within the crater of Mount St. Helens.

  6. Fractional Erbium laser in the treatment of photoaging: randomized comparative, clinical and histopathological study of ablative (2940nm) vs. non-ablative (1540nm) methods after 3 months*

    PubMed Central

    Borges, Juliano; Cuzzi, Tullia; Mandarim-de-Lacerda, Carlos Alberto; Manela-Azulay, Mônica

    2014-01-01

    BACKGROUND Fractional non-ablative lasers keep the epidermis intact, while fractional ablative lasers remove it, making them theoretically more effective. OBJECTIVES To evaluate the clinical and histological alterations induced by fractional photothermolysis for treating photoaging, comparing the possible equivalence of multiple sessions of 1540nm Erbium, to one session of 2940nm Erbium. METHODS Eighteen patients (mean age 55.9) completed the treatment with three sessions of 1540nm fractional Erbium laser on one side of the face (50 mJ/mB, 15ms, 2 passes), and one session of 2940nm on the other side (5mJ/mB, 0.25ms, 2 passes). Biopsies were performed before and 3 months after treatment. Clinical, histological and morphometric evaluations were carried out. RESULTS All patients presented clinical improvement with no statistically significant difference (p> 0.05) between the treated sides. Histopathology revealed a new organization of collagen and elastic fibers, accompanied by edema, which was more evident with the 2940nm laser. This finding was confirmed by morphometry, which showed a decrease in collagen density for both treatments, with a statistical significance for the 2940nm laser (p > 0.001). CONCLUSIONS Three 1540nm sessions were clinically equivalent to one 2940nm session. The edema probably contributed to the positive results after three months, togheter with the new collagen and elastic fibers organization. The greater edema after the 2940nm session indicates that dermal remodeling takes longer than with 1540nm. It is possible that this histological superiority relates to a more prolonged effect, but a cohort longer than three months is needed to confirm that supposition. PMID:24770501

  7. Specific features of daytime long-period pulsations observed during the solar wind impulse against a background of the substorm of August 1, 1998

    NASA Astrophysics Data System (ADS)

    Klibanova, Yu. Yu.; Mishin, V. V.; Tsegmed, B.

    2014-11-01

    Long-period geomagnetic pulsations in the (1.7-6.7) mHz frequency range at 18.25-18.48 UT on August 1, 1998, caused by several successive sudden changes in the solar wind (SW) dynamic pressure, are studied against a background of substorm intensification. The data of the ground stations, which were near local noon (the CANOPUS Canadian network) and on the nightside (the auroral stations in Yakutia and at the IMAGE network), and the INTERBALL-1, ACE, WIND, and GOES 8, extramagnetospheric satellites are used. The effect of the SW plasma and IMF parameters, SW inhomogeneity front inclination, and geomagnetic activity on the pulsation propagation and polarization direction and amplitude is discussed. The properties of pulsations, recorded before the substorm, correspond to the pulsation excitation by the inhomogeneity front incident on the magnetopause during the magnetically quiet period: pulsations propagate from the contact point onto the nightside when the amplitude increases and the polarization sense of rotation is opposite on the dawn and dusk sides. Substorm intensification results in the propagation direction reversal and in a more complex behavior of the pulsation amplitude and polarization on the dayside.

  8. Trends in the prevalence of heart diseases over a ten-year period from single-center observations based on a large echocardiographic database.

    PubMed

    Lu, Hao; Pan, Wen-zhi; Wan, Quan; Cheng, Lei-lei; Shu, Xian-hong; Pan, Cui-zhen; Qian, Ju-ying; Ge, Jun-bo

    2016-01-01

    There is a paucity of data regarding trends in the incidence of heart disease in China during recent years. Using a large echocardiography database in our center, we analyzed trends in the prevalence of several common heart diseases from Dec. 2003. This study retrospectively analyzed the echocardiographic database in our Department from 2003 to 2012. A total of 385 682 cases were included in the study. The prevalence of rheumatic heart disease decreased over the 10-year period, from 4.04% in 2003 to 3.06% in 2012 (P<0.01). Infective endocarditis also decreased, from a mean prevalence of 0.37% in July 2003 to 0.27% in Dec. 2008 (P<0.001). The prevalence of hypertrophic cardiomyopathy, which includes 20% apical hypertrophic cardiomyopathy and 20% hypertrophic obstructive cardiomyopathy, was about 1.8%. The prevalence of the three most common adult congenital heart diseases (CHDs) decreased by about 10% from July 2003 to Dec. 2008 (all P<0.001). The prevalence of moderate pulmonary arterial hypertension (PAH) or left ventricular systolic dysfunction (LVSD) decreased during the 10-year period (P<0.001), but there was no change in the prevalence of severe PAH or LVSD (P>0.05). The present study indirectly demonstrates that the prevalence of several common heart diseases in China has declined in recent years.

  9. NIMBUS-7 SBUV (Solar Backscatter Ultraviolet) observations of solar UV spectral irradiance variations caused by solar rotation and active-region evolution for the period November 7, 1978 - November 1, 1980

    NASA Technical Reports Server (NTRS)

    Heath, D. F.; Repoff, T. P.; Donnelly, R. F.

    1984-01-01

    Observations of temporal variations of the solar UV spectral irradiance over several days to a few weeks in the 160-400 nm wavelength range are presented. Larger 28-day variations and a second episode of 13-day variations occurred during the second year of measurements. The thirteen day periodicity is not a harmonic of the 28-day periodicity. The 13-day periodicity dominates certain episodes of solar activity while others are dominated by 28-day periods accompanied by a week 14-day harmonic. Techniques for removing noise and long-term trends are described. Time series analysis results are presented for the Si II lines near 182 nm, the Al I continuum in the 190 nm to 205 nm range, the Mg I continuum in the 210 nm to 250 nm range, the MgII H & K lines at 280 nm, the Mg I line at 285 nm, and the Ca II K & H lines at 393 and 397 nm.

  10. Long-term observations of saccharides in remote marine aerosols from the western North Pacific: A comparison between 1990-1993 and 2006-2009 periods

    NASA Astrophysics Data System (ADS)

    Chen, Jing; Kawamura, Kimitaka; Liu, Cong-Qiang; Fu, Pingqing

    2013-03-01

    Anhydrosugars (galactosan, mannosan and levoglucosan), sugars (xylose, fructose, glucose, sucrose and trehalose) and sugar alcohols (erythritol, arabitol, mannitol and inositol) were measured in the aerosol samples collected in a remote island (Chichi-Jima, Japan) in the western North Pacific from 1990 to 1993 and from 2006 to 2009. Total concentrations of anhydrosugars, the biomass burning tracers, were 0.01-5.57 ng m-3 (average 0.76 ng m-3) during 1990-1993 versus 0.01-7.19 ng m-3 (0.64 ng m-3) during 2006-2009. Their seasonal variations were characterized by winter/spring maxima and summer/fall minima. Such a seasonal pattern should be caused by the enhanced long-range atmospheric transport of biomass burning products and terrestrial organic matter (such as higher plant detritus and soil dust) from the Asian continent in winter/spring seasons, when the westerly or winter monsoon system prevails over the western North Pacific. Sugars and sugar alcohols showed different seasonal patterns. The monthly mean concentrations of erythritol, arabitol, mannitol, inositol, fructose, glucose and trehalose were found to be higher in spring/summer and lower in fall/winter during both 1990-1993 and 2006-2009 periods, indicating an enhanced biogenic emission of aerosols in warm seasons. Interestingly, saccharides showed a gradual decrease in their concentrations from 1991 to 1993 and an increase from 2006 to 2009. In addition, the monthly averaged concentrations of sugars and sugar alcohols showed maxima in early summer during 1990-1993, which occurred about 1-2 months earlier than those during 2006-2009. Such a clear seasonal shift may be attributable to the changes in the strength of westerly and trade wind systems during two periods.

  11. Response of the Mediterranean Sea thermohaline circulation to observed changes in the winter wind stress field in the period 1980-1993

    NASA Astrophysics Data System (ADS)

    Samuel, Sarah; Haines, Keith; Josey, Simon; Myers, Paul G.

    1999-04-01

    This paper seeks to model changes in deep water production in the eastern Mediterranean induced by changes in winter wind stress. An analysis of individual monthly wind stress fields over the Mediterranean for 1980-1993 from the SOC flux data set shows that an intensification of the winter mean (mainly January) wind stress over the Aegean Sea and Levantine basin occurred in the latter half of this period. A weakening of the Mistral occurred at the same time. Two monthly wind stress climatologies were created using the 1980-1987 and 1988-1993 periods, and these were used to force an ocean general circulation model of the Mediterranean, with climatological surface T, S relaxation. The Levantine intermediate water (LIW) dispersal path in the Ionian is altered in the 1988-1993 experiment with no pathway to the Adriatic and, consequently, greatly reduced exchange at Otranto and a collapse in Adriatic deep water formation. In contrast, there is an increased exchange of LIW at the Cretan arc straits and enhanced Aegean deep water production in the 1988-1993 experiment. Much more Aegean water exits into the Levantine and Ionian basins as is shown by an east-west cross section south of Crete, along a similar path to the Meteor cruise in 1995. Changes in air-sea fluxes are diagnosed from the model showing a small increase in wintertime cooling over the Aegean and reduced cooling over the Adriatic after 1987. While the changes in air-sea fluxes are probably underrepresented by this simulation, the large changes induced by the wind forcing suggest this could be a mechanism in the altered thermohaline state of the eastern Mediterranean since 1987.

  12. Analytical microscopy observations of rat enterocytes after oral administration of soluble salts of lanthanides, actinides and elements of group III-A of the periodic chart.

    PubMed

    Floren, C; Tekaya, L; Escaig, F; Labejof, L; Mouthon, G; Galle, P

    2001-05-01

    The behavior in the intestinal barrier of nine elements (three of the group III-A, four lanthanides and two actinides), absorbed as soluble salts, has been studied by two microanalytical methods: electron probe X-ray micro analysis (EPMA) and secondary ion mass spectrometry (SIMS). It has been shown that the three elements of group III-A, aluminium, gallium and indium; and the four lanthanides, lanthanum, cerium, europium and thulium, are selectively concentrated and precipitated as non-soluble form in enterocytes of proximal part of the intestinal tract. SIMS microscopy has shown that these elements are concentrated as a number of submicroscopic precipitates, most of them localized in the apical part of the duodenum enterocytes, where they are observed from one hour to 48 hr after a single intragastric administration. No precipitate is observed after three days. It is suggested that this mechanism of local concentration limits the diffusion of these elements through the digestive barrier, some of them being toxic and none of them having a recognized physiological role. Additionally, the precipitation in duodenal enterocytes, the life time of which is on the order of 2-3 days, allows the elements absorbed as soluble form to be eliminated as a non-soluble form in the digestive lumen along with the desquamation of the apoptotic enterocytes. The intracytoplasmic localization of the precipitates are supposed to be the lysosomes although no direct evidence could be given here due to the very small sizes of the lysosomes of enterocytes. The same results were not observed with the two studied actinides. After administration of thorium, only some very sparse microprecipitates could be observed in intestinal mucosa and, after administration of uranium, no precipitates were observed with the exception of some in the conjunctive part of the duodenal villi.

  13. Constraints on Long-period Planets from an L'- and M-band Survey of Nearby Sun-like Stars: Observations

    NASA Astrophysics Data System (ADS)

    Heinze, A. N.; Hinz, Philip M.; Sivanandam, Suresh; Kenworthy, Matthew; Meyer, Michael; Miller, Douglas

    2010-05-01

    We present the observational results of an L'- and M-band adaptive optics imaging survey of 54 nearby, Sun-like stars for extrasolar planets, carried out using the Clio camera on the MMT. We have concentrated more strongly than all other planet-imaging surveys to date on very nearby F, G, and K stars, prioritizing stellar proximity higher than youth. Ours is also the first survey to include extensive observations in the M band, which supplement the primary L' observations. Models predict much better planet/star flux ratios at the L' and M bands than at more commonly used shorter wavelengths (i.e., the H band). We have carried out extensive blind simulations with fake planets inserted into the raw data to verify our sensitivity, and to establish a definitive relationship between source significance in σ and survey completeness. We find 97% confident-detection completeness for 10σ sources, but only 46% for 7σ sources—raising concerns about the standard procedure of assuming high completeness at 5σ, and demonstrating that blind sensitivity tests to establish the significance-completeness relation are an important analysis step for all planet-imaging surveys. We discovered a previously unknown ~0.15 M sun stellar companion to the F9 star GJ 3876, at a projected separation of about 80 AU. Twelve additional candidate faint companions are detected around other stars. Of these, 11 are confirmed to be background stars and one is a previously known brown dwarf. We obtained sensitivity to planetary-mass objects around almost all of our target stars, with sensitivity to objects below 3 M Jup in the best cases. Constraints on planet populations based on this null result are presented in our Modeling Results paper. Observations reported here were obtained at the MMT Observatory, a joint facility of the University of Arizona and the Smithsonian Institution.

  14. Observations of open-ocean deep convection in the northwestern Mediterranean Sea: Seasonal and interannual variability of mixing and deep water masses for the 2007-2013 Period

    NASA Astrophysics Data System (ADS)

    Houpert, L.; Durrieu de Madron, X.; Testor, P.; Bosse, A.; D'Ortenzio, F.; Bouin, M. N.; Dausse, D.; Le Goff, H.; Kunesch, S.; Labaste, M.; Coppola, L.; Mortier, L.; Raimbault, P.

    2016-11-01

    We present here a unique oceanographic and meteorological data set focus on the deep convection processes. Our results are essentially based on in situ data (mooring, research vessel, glider, and profiling float) collected from a multiplatform and integrated monitoring system (MOOSE: Mediterranean Ocean Observing System on Environment), which monitored continuously the northwestern Mediterranean Sea since 2007, and in particular high-frequency potential temperature, salinity, and current measurements from the mooring LION located within the convection region. From 2009 to 2013, the mixed layer depth reaches the seabed, at a depth of 2330m, in February. Then, the violent vertical mixing of the whole water column lasts between 9 and 12 days setting up the characteristics of the newly formed deep water. Each deep convection winter formed a new warmer and saltier "vintage" of deep water. These sudden inputs of salt and heat in the deep ocean are responsible for trends in salinity (3.3 ± 0.2 × 10-3/yr) and potential temperature (3.2 ± 0.5 × 10-3 C/yr) observed from 2009 to 2013 for the 600-2300 m layer. For the first time, the overlapping of the three "phases" of deep convection can be observed, with secondary vertical mixing events (2-4 days) after the beginning of the restratification phase, and the restratification/spreading phase still active at the beginning of the following deep convection event.

  15. Swift-XRT observations of Quasi-periodic oscillations seen in the Super Soft Source emission from Classical and Recurrent Novae

    NASA Astrophysics Data System (ADS)

    Beardmore, Andrew

    2016-07-01

    We report short timescale, soft X-ray flux quasi-periodic oscillations that have been seen by the Swift X-ray Telescope (XRT) during the super soft source (SSS) emission phase from novae. A periodogram analysis revealed oscillations were visible in the 0.3-10 keV XRT light curves obtained from RS Oph (period, P=35.0 s), KT Eri (P=34.9s), V339 Del (P=54.0s), and V5668 Sgr (P=69.7s), with fractional rms variabilities ranging from 1-8 per cent. During day 32-59 of the RS Oph outburst, the oscillation central frequency appeared quite variable, ranging from 26.2-31.1 mHz, caused by a lower coherence at this time. However, after day 50 the oscillation became more coherent, with a frequency that slowly increased from 28.3-28.9 mHz over 9 days, before the trend reversed. The oscillation frequency was less variable in KT Eri and V339 Del. No other correlations, such as between the oscillation frequency or amplitude with source intensity, were seen. A wavelet analysis of the variability seen in RS Oph, KT Eri and V339 Del revealed the oscillations were sometimes visible for entire XRT snapshots lasting 1.0-1.5 ks, yet on other occasions, they were detected for only ˜120 s (i.e. ˜2-4 cycles). The modulation fractional amplitude was variable, occasionally reaching values of 15-20 per cent for a few cycles. During times when the coherence was low, the oscillation phase was seen to jump by ˜0.4-0.6 cycles in RS Oph, then remain stable for ˜10 cycles. KT Eri showed smaller phase jumps of ˜0.2 cycles. We detect a significant spectral variation through the 35s oscillation seen in RS~Oph, with the spectrum becoming harder at the time of the modulation maximum. Fits to the oscillation maximum and minima spectra suggest the increased flux between 0.6-0.75 keV in the former is caused by a 25 per cent reduction in the neutral oxygen column density at this phase. We discuss the possible origins behind the oscillations.

  16. Period Pain

    MedlinePlus

    ... You may also have other symptoms, such as lower back pain, nausea, diarrhea, and headaches. Period pain is not ... Taking a hot bath Doing relaxation techniques, including yoga and meditation You might also try taking over- ...

  17. Periodized wavelets

    SciTech Connect

    Schlossnagle, G.; Restrepo, J.M.; Leaf, G.K.

    1993-12-01

    The properties of periodized Daubechies wavelets on [0,1] are detailed and contrasted against their counterparts which form a basis for L{sup 2}(R). Numerical examples illustrate the analytical estimates for convergence and demonstrate by comparison with Fourier spectral methods the superiority of wavelet projection methods for approximations. The analytical solution to inner products of periodized wavelets and their derivatives, which are known as connection coefficients, is presented, and several tabulated values are included.

  18. Field observation of morpho-dynamic processes during storms at a Pacific beach, Japan: role of long-period waves in storm-induced berm erosion.

    PubMed

    Mizuguchi, Masaru; Seki, Katsumi

    2015-01-01

    Many ultrasonic wave gages were placed with a small spacing across the swash zone to monitor either sand level or water level. Continuous monitoring conducted for a few years enabled the collection of data on the change in wave properties as well as swash-zone profiles. Data sets including two cases of large-scale berm erosion were analyzed. The results showed that 1) shoreline erosion started when high waves with significant power in long-period (1 to 2 min.) waves reached the top of a well-developed berm with the help of rising tide; 2) the beach in the swash zone was eroded with higher elevation being more depressed, while the bottom elevation just outside the swash zone remained almost unchanged; and 3) erosion stopped in a few hours after the berm was completely eroded or the swash-zone slope became uniformly mild. These findings strongly suggest that long waves play a dominant role in the swash-zone dynamics associated with these erosional events.

  19. Observations on changes in abundance of questing Ixodes ricinus, castor bean tick, over a 35-year period in the eastern part of its range (Russia, Tula region).

    PubMed

    Korotkov, Yu; Kozlova, T; Kozlovskaya, L

    2015-06-01

    Ixodes ricinus (Acari: Ixodidae) L. transmit a wide variety of pathogens to vertebrates including viruses, bacteria and protozoa. Understanding of the epidemiology of tick-borne infections requires basic knowledge of the regional and local factors influencing tick population dynamics. The present study describes the results of monitoring of a questing I. ricinus population, conducted over 35 years (1977-2011) in the eastern, poorly studied part of its range (Russia, Tula region). We have found that the multiannual average abundance of ticks is small and varies depending on the biotope and degree of urban transformation. Tick abundance for the first 14 years of observations (1977-1990) was at the lower limit of the sensitivity of our methods throughout the study area (0.1-0.9 specimens per 1-km transect). In the following 21 years (1991-2011), a manifold increase in abundance was observed, which reached 18.1 ± 1.8 individuals per 1-km transect in moist floodplain terraces, and 4.8 ± 0.9 in xerophylic hill woods. Long-term growth of tick abundance occurred in spite of a relatively constant abundance of small mammals and only minor fluctuations in the abundance of large wild animals. Climate and anthropogenic changes appear to be the main contributors to increased abundance of the tick.

  20. Arctic Ocean circulation, processes and water masses: A description of observations and ideas with focus on the period prior to the International Polar Year 2007-2009

    NASA Astrophysics Data System (ADS)

    Rudels, Bert

    2015-03-01

    The evolving knowledge of the Arctic Ocean, its hydrography and its water masses and their transformations and circulation is reviewed starting with the observations made on Fram 1893-1896 and extending to the International Polar Year (IPY) 2007-2009. The expeditions and observations after Fram to the mid 20th century as well as the more extensive and systematic studies of water masses and circulation made from ice stations and airborne expeditions from the late 1940s to the late 1970s are briefly described. The early concepts of the connections and exchanges between the Arctic Ocean and the world ocean are also discussed. In the 1980s scientific icebreakers were beginning to enter the inner parts of the Arctic Ocean and large international programmes were launched, culminating in the IPY. The changes in the Arctic Ocean, first noted in the Atlantic layer in 1990 and shortly after in the upper layers, are described. The exchanges between the Arctic Ocean and the surrounding seas through the four main openings, Fram Strait, Barents Sea, Bering Strait and the Canadian Arctic Archipelago as well the volume and freshwater balances of the Arctic Ocean are examined.

  1. Periodic chiral structures

    NASA Technical Reports Server (NTRS)

    Jaggard, Dwight L.; Engheta, Nader; Pelet, Philippe; Liu, John C.; Kowarz, Marek W.; Kim, Yunjin

    1989-01-01

    The electromagnetic properties of a structure that is both chiral and periodic are investigated using coupled-mode equations. The periodicity is described by a sinusoidal perturbation of the permittivity, permeability, and chiral admittance. The coupled-mode equations are derived from physical considerations and used to examine bandgap structure and reflected and transmitted fields. Chirality is observed predominantly in transmission, whereas periodicity is present in both reflection and transmission.

  2. Revisiting the Brazilian scenario of registry and protection of cultivars: an analysis of the period from 1998 to 2010, its dynamics and legal observations.

    PubMed

    Marinho, C D; Martins, F J O; Amaral, S C S; Amaral Júnior, A T; Gonçalves, L S A; de Mello, M P

    2011-05-03

    During the last 20 years, the national production of grains has increased 156.1%; productivity increased 93.8% and there has been an increase of 29.1% in cultivated area. Currently, agribusiness is responsible for 40% of Brazilian exports. Nevertheless, there is little quantitative information on the main plant species of economic interest that have been registered and protected in the Agriculture, Fisheries and Food Supply Ministry (MAPA) by public and private companies, as well as by public-private partnerships. Consequently, we investigated the registry and protection of 27 species of economic interest, including the 15 that are the basis of the Brazilian diet, based on the information available on the site CultivarWeb, of MAPA, for the period from 1998 to August 30, 2010. We also examined the legislation that regulates registration and protection procedures and its implications for plant breeding and plant product development. It was found that the private sector controls 73.1% of the registrations and 53.56% of the protections, while 10.73% of the protections were of material developed overseas. Public-private partnerships contributed little to the development of new cultivars, with 0.5% of the registries and 3.61% of the protections. We conclude that plant protection directed private investment to development of wheat and rice varieties, with the greatest public investments directed to corn and sorghum. After the Cultivar Protection Law was implemented, there was restriction of access to germplasm banks, which could inhibit advances in Brazilian plant breeding programs, indicating a need for revision of this legal barrier.

  3. Spectral Index and Quasi-Periodic Oscillation Frequency Correlation in Black Hole (BH) Sources: Observational Evidence of Two Phases and Phase Transition in BHs

    NASA Technical Reports Server (NTRS)

    Titarchuk, Lev; Fiorito, Ralph

    2004-01-01

    Recent studies have shown that strong correlations are observed between the low frequencies (1-10 Hz) of quasiperiodic oscillations (QPOs) and the spectral power law index of several Black Hole (BH) candidate sources, in low hard states, steep power-law (soft) states and in transition between these states. The observations indicate that the X-ray spectrum of such state (phases) show the presence of a power-law component and are sometimes related to simultaneous radio emission indicated the probable presence of a jet. Strong QPOs (less than 20% rms) are present in the power density spectrum in the spectral range where the power-law component is dominant ( i.e. 60-90% ). This evidence contradicts the dominant long standing interpretation of QPOs as a signature of the thermal accretion disk. We present the data from the literature and our own data to illustrate the dominance of power-law index-QPO frequency correlations. We provide a model, that identifies and explains the origin of the QPOs and how they are imprinted on the properties of power-law flux component. We argue the existence of a bounded compact coronal region which is a natural consequence of the adjustment of Keplerian disk flow to the innermost sub-Keplerian boundary conditions near the central object and that ultimately leads to the formation of a transition layer (TL) between the adjustment radius and the innermost boundary. The model predicts two phases or states dictated by the photon upscattering produced in the TL: (1) hard state, in which the TL is optically thin and very hot (kT approx. greater than 50 keV) producing photon upscattering via thermal Componization; the photon spectrum index Gamma appprox.1.5 for this state is dictated by gravitational energy release and Compton cooling in an optically thin shock near the adjustment radius; (2) a soft state which is optically thick and relatively cold (approx. less than 5 keV); the index for this state, Gamma approx. 2.8 is determined by soft

  4. Liver graft hyperperfusion in the early postoperative period promotes hepatic regeneration 2 weeks after living donor liver transplantation: A prospective observational cohort study.

    PubMed

    Byun, Sung Hye; Yang, Hae Soo; Kim, Jong Hae

    2016-11-01

    velocities and a small-sized graft in the early postoperative period contributes to hepatic regeneration 2 weeks after LDLT.

  5. Results of a search for daily and annual variations of the 214Po half-life at the two year observation period

    NASA Astrophysics Data System (ADS)

    Alexeyev, E. N.; Gavrilyuk, Yu. M.; Gangapshev, A. M.; Kazalov, V. V.; Kuzminov, V. V.; Panasenko, S. I.; Ratkevich, S. S.

    2016-11-01

    The brief description of installation TAU-2 intended for long-term monitoring of the half-life value τ( T 1/2) of the 214Po is presented. The methods of measurement and processing of collected data are reported. The results of analysis of time series values of τ with different time step are presented. Total measurement time was equal to 590 days. Averaged value of the 214Po half-life was obtained τ = 163.46 ± 0.04 μs. The annual variation with an amplitude A = (8.9 ± 2.3) × 10-4, solar-daily variation with an amplitude A So = (7.5 ± 1.2) × 10-4, lunar-daily variation with an amplitude A L = (6.9 ± 2.0) × 10-4 sidereal-daily variation with an amplitude A S = (7.2 ± 1.2) × 10-4 were found in a series of τ values. The maximal values of amplitude are observed at the moments when the projections of the installation Earth location velocity vectors toward the source of possible variation achieve its maximal magnitudes.

  6. Annual water-level measurements in observation wells, 1951-1955, and atlas of maps showing changes in water levels for various periods from beginning of record through 1954, New Mexico

    USGS Publications Warehouse

    Reeder, Harold O.

    1959-01-01

    This report tabulates the annual measurements of water level in the observation wells in the various irrigated areas, primarily from 1951 through 1955. It summarizes changes in water level by discussion and with an atlas of nearly all the maps of change of water level for the period of record to 1955 for each area in which observations are being made. Included also are hydrographs for the period of record through 1954 of several selected wells in the various areas irrigated from ground-water sources. The annual measurements of water level before 1951, seasonal measurements, and daily records of water levels in wells equipped with recording gages have been published in an annual series of U. S. Geological Survey water-supply papers.

  7. The state of the atmosphere as inferred from the FGGE satellite observing systems during SOP-1. [special observing period (SOP-1) of First Global Atmospheric Research Program Global Experiment (FGGE)

    NASA Technical Reports Server (NTRS)

    Halem, M.; Kalnay-Rivas, E.; Baker, W. E.; Atlas, R.

    1981-01-01

    The statistical properties, and coverage, of satellite temperature sounding data are described. Tropical regions are observed every two days, extratropics from one to four times a day. Oceans are covered two to three times a day. Asynoptic coverage is comparable to the U.S. rawinsonde network twice daily coverage. Lack of ground truth for data sparse areas makes accuracy difficult to assess. The rms differences of layer mean temperatures obtained from collocating rawinsonde observations with satellite temperature profiles in space and time differ from rms differences of layer mean satellite temperature soundings. The FGGE satellite systems can infer the three dimensional motion field and improve the representation of the large scale state of the atmosphere.

  8. Periodic Polymers

    NASA Astrophysics Data System (ADS)

    Thomas, Edwin

    2013-03-01

    Periodic polymers can be made by self assembly, directed self assembly and by photolithography. Such materials provide a versatile platform for 1, 2 and 3D periodic nano-micro scale composites with either dielectric or impedance contrast or both, and these can serve for example, as photonic and or phononic crystals for electromagnetic and elastic waves as well as mechanical frames/trusses. Compared to electromagnetic waves, elastic waves are both less complex (longitudinal modes in fluids) and more complex (longitudinal, transverse in-plane and transverse out-of-plane modes in solids). Engineering of the dispersion relation between wave frequency w and wave vector, k enables the opening of band gaps in the density of modes and detailed shaping of w(k). Band gaps can be opened by Bragg scattering, anti-crossing of bands and discrete shape resonances. Current interest is in our group focuses using design - modeling, fabrication and measurement of polymer-based periodic materials for applications as tunable optics and control of phonon flow. Several examples will be described including the design of structures for multispectral band gaps for elastic waves to alter the phonon density of states, the creation of block polymer and bicontinuous metal-carbon nanoframes for structures that are robust against ballistic projectiles and quasi-crystalline solid/fluid structures that can steer shock waves.

  9. Complementary Effects of Genetic Variations in LEPR on Body Composition and Soluble Leptin Receptor Concentration after 3-Month Lifestyle Intervention in Prepubertal Obese Children

    PubMed Central

    Gajewska, Joanna; Kuryłowicz, Alina; Mierzejewska, Ewa; Ambroszkiewicz, Jadwiga; Chełchowska, Magdalena; Weker, Halina; Puzianowska-Kuźnicka, Monika

    2016-01-01

    In obese individuals, weight loss might be affected by variants of the adipokine-encoding genes. We verified whether selected functional single nucleotide polymorphisms in LEP, LEPR and ADIPOQ are associated with changes in serum levels of the respective adipokines and weight loss in 100 prepubertal obese (SDS-BMI > 2) Caucasian children undergoing lifestyle intervention. Frequencies of the -2548G > A LEP, Q223R LEPR, K656N LEPR, -11377C > G and -11426A > G ADIPOQ polymorphisms were analyzed by restriction fragment length polymorphism. Serum adipokine and soluble leptin receptor (sOB-R) concentrations were measured using the ELISA method. Among the analyzed polymorphisms, only LEPR polymorphisms were associated with changes of SDS-BMI or sOB-R concentrations in children after therapy. Carriers of the wild-type K665N and at least one minor Q223R allele had the greatest likelihood of losing weight (OR = 5.09, p = 0.006), an increase in sOB-R (ptrend = 0.022) and decrease in SDS-BMI correlated with the decrease of fat mass (p < 0.001). In contrast, carrying of the wild-type Q223R and at least one minor K665N allele were associated with a decrease in sOB-R concentrations and a decrease in SDS-BMI correlated with a decrease in fat-free mass (p = 0.002). We suggest that the combination of different LEPR variants, not a single variant, might determine predisposition to weight loss in the prepubertal period. PMID:27240401

  10. Switching from serotonin reuptake inhibitors to agomelatine in patients with refractory obsessive-compulsive disorder: a 3 month follow-up case series

    PubMed Central

    2011-01-01

    Background Serotonin reuptake inhibitors (SRIs) currently represent the cornerstone of obsessive-compulsive disorder (OCD) pharmacotherapy. However, OCD is characterized by high rates of partial and/or absent response to standard, recommended treatments, often prompting pharmacological and non-pharmacological augmentation or switching of strategies. Agomelatine, a novel melatonin agonist and selective serotonin antagonist (MASSA) antidepressant approved for major depressive disorder (MDD) has recently been additionally proposed as a treatment for anxiety disorders such as social anxiety disorder (SAD) and panic disorder (PD), but not yet OCD. Nonetheless, agomelatine may have a role in the management of OCD, essentially due to its anxiolytic 5-hydroxytryptamine (HT)2C blockade action, while melatonin (MT)1 and MT2 modulation might contribute to circadian rhythm restoration if impaired. Methods This case series reports the outcome of six patients with or without comorbid mood and/or other anxiety disorders who were treated with SRIs at adequate doses for at least 8 weeks, showing partial or no response. Patients were then switched to agomelatine 50 mg/day, and followed up for 12 weeks. Results Three out of six patients, in particular those with relevant circadian rhythm subjective impairment, showed a Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score reduction of ≥35%. No relevant side effects were observed, but initial, transient, self-remitting dizziness in one patient and weight gain in another were seen. Conclusions Although clinical confounding factors (subthreshold bipolarity and eventually the presence of impaired circadian rhythms) and methodological boundaries (lack of control and neurophysiological recording, tiny sample size and short follow-up) limit the validity of this preliminary observation, it does indicate agomelatine may have a role in some SRI-refractory OCD cases, thus prompting the validity of investigation by further controlled studies

  11. Lidar observations of persistent gravity waves with periods of 3-10 h in the Antarctic middle and upper atmosphere at McMurdo (77.83°S, 166.67°E)

    NASA Astrophysics Data System (ADS)

    Chen, Cao; Chu, Xinzhao; Zhao, Jian; Roberts, Brendan R.; Yu, Zhibin; Fong, Weichun; Lu, Xian; Smith, John A.

    2016-02-01

    Persistent, dominant, and large-amplitude gravity waves with 3-10 h periods and vertical wavelengths ~20-30 km are observed in temperatures from the stratosphere to lower thermosphere with an Fe Boltzmann lidar at McMurdo, Antarctica. These waves exhibit characteristics of inertia-gravity waves in case studies, yet they are extremely persistent and have been present during every lidar observation. We characterize these 3-10 h waves in the mesosphere and lower thermosphere using lidar temperature data in June from 2011 to 2015. A new method is applied to identify the major wave events from every lidar run longer than 12 h. A continuous 65 h lidar run on 28-30 June 2014 exhibits a 7.5 h wave spanning ~60 h, and 6.5 h and 3.4 h waves spanning 40 and 45 h, respectively. Over the course of 5 years, 323 h of data in June reveal that the major wave periods occur in several groups centered from ~3.5 to 7.5 h, with vertical phase speeds of 0.8-2 m/s. These 3-10 h waves possess more than half of the spectral energy for ~93% of the time. A rigorous prewhitening, postcoloring technique is introduced for frequency power spectra investigation. The resulting spectral slopes are unusually steep (-2.7) below ~100 km but gradually become shallower with increasing altitude, reaching about -1.6 at 110 km. Two-dimensional fast Fourier transform spectra confirm that these waves have a uniform dominant vertical wavelength of 20-30 km across periods of 3.5-10 h. These statistical features shed light on the wave source and pave the way for future research.

  12. Circulating Levels of Hormones, Lipids, and Immune Mediators in Post-Traumatic Stress Disorder – A 3-Month Follow-Up Study

    PubMed Central

    Jergović, Mladen; Bendelja, Krešo; Savić Mlakar, Ana; Vojvoda, Valerija; Aberle, Neda; Jovanovic, Tanja; Rabatić, Sabina; Sabioncello, Ante; Vidović, Anđelko

    2015-01-01

    A number of peripheral blood analytes have been proposed as potential biomarkers of post-traumatic stress disorder (PTSD). Few studies have investigated whether observed changes in biomarkers persist over time. The aim of this study was to investigate the association of combat-related chronic PTSD with a wide array of putative PTSD biomarkers and to determine reliability of the measurements, i.e., correlations over time. Croatian combat veterans with chronic PTSD (n = 69) and age-matched healthy controls (n = 32), all men, were assessed at two time points separated by 3 months. Serum levels of lipids, cortisol, dehydroepiandrosterone-sulfate (DHEA-S), prolactin, and C-reactive protein were determined. Multiplex assay was used for the simultaneous assessment of 13 analytes in sera: cytokines [interferon-γ, interleukin (IL)-1β, IL-2, IL-4, IL-6, TNF-α], adhesion molecules (sPECAM-1, sICAM-1), chemokines (IL-8 and MIP-1α), sCD40L, nerve growth factor, and leptin. Group differences and changes over time were tested by parametric or non-parametric tests, including repeated measures analysis of covariance. Reliability estimates [intraclass correlation coefficient (ICC) and kappa] were also calculated. Robust associations of PTSD with higher levels of DHEA-S [F(1,75) = 8.14, p = 0.006)] and lower levels of prolactin [F(1,75) = 5.40, p = 0.023] were found. Measurements showed good to excellent reproducibility (DHEA-S, ICC = 0.50; prolactin, ICC = 0.79). Serum lipids did not differ between groups but significant increase of LDL-C after 3 months was observed in the PTSD group (t = 6.87, p < 0.001). IL-8 was lower in the PTSD group (t = 4.37, p < 0.001) but assessments showed poor reproducibility (ICC = −0.08). Stable DHEA-S and prolactin changes highlight their potential to be reliable markers of PTSD. Change in lipid profiles after 3 months suggests that PTSD patients may be more prone to hyperlipidemia. High

  13. A minimum of 3 months of dietary fish oil supplementation is required to raise amygdaloid afterdischarge seizure thresholds in rats--implications for treating complex partial seizures.

    PubMed

    Taha, Ameer Y; Trepanier, Marc-Olivier; Ciobanu, Flaviu A; Taha, Nadeen M; Ahmed, Muaz; Zeng, Qiudi; Cheuk, Waiyin I; Ip, Bryan; Filo, Elvis; Scott, Brian W; Burnham, W M; Bazinet, Richard P

    2013-04-01

    Complex partial seizures, which typically originate in limbic structures such as the amygdala, are often resistant to antiseizure medications. Our goal was to investigate the effects of chronic dietary supplementation with n-3 polyunsaturated fatty acids (PUFAs) derived from fish oil on seizure thresholds in the amygdala, as well as on blood and brain PUFA levels. The acute effects of injected n-3 PUFAs--eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)--were also tested in the maximal pentylenetetrazol (PTZ) seizure model. In amygdala-implanted subjects, fish oil supplementation significantly increased amygdaloid afterdischarge thresholds, as compared with controls at 3, 5, and 7 months after the start of supplementation. Fish oil supplementation also increased serum EPA and DHA concentrations. DHA concentration in the pyriform-amygdala area increased in the fish-oil treated group by 17-34%, but this effect did not reach statistical significance (P=0.065). DHA significantly increased the latency to seizure onset in the PTZ seizure model, whereas EPA had no significant effect. These observations suggest that chronic dietary fish oil supplementation can raise focal amygdaloid seizure thresholds and that this effect is likely mediated by DHA rather than by EPA.

  14. Gene Therapy Rescues Cone Structure and Function in the 3-Month-Old rd12 Mouse: A Model for Midcourse RPE65 Leber Congenital Amaurosis

    PubMed Central

    Li, Xia; Li, Wensheng; Dai, Xufeng; Kong, Fansheng; Zheng, Qinxiang; Zhou, Xiangtian; Lü, Fan; Chang, Bo; Rohrer, Bärbel; Hauswirth, William. W.; Qu, Jia; Pang, Ji-jing

    2011-01-01

    Purpose. RPE65 function is necessary in the retinal pigment epithelium (RPE) to generate chromophore for all opsins. Its absence results in vision loss and rapid cone degeneration. Recent Leber congenital amaurosis type 2 (LCA with RPE65 mutations) phase I clinical trials demonstrated restoration of vision on RPE65 gene transfer into RPE cells overlying cones. In the rd12 mouse, a naturally occurring model of RPE65-LCA early cone degeneration was observed; however, some peripheral M-cones remained. A prior study showed that AAV-mediated RPE65 expression can prevent early cone degeneration. The present study was conducted to test whether the remaining cones in older rd12 mice can be rescued. Methods. Subretinal treatment with the scAAV5-smCBA-hRPE65 vector was initiated at postnatal day (P)14 and P90. After 2 months, electroretinograms were recorded, and cone morphology was analyzed by using cone-specific peanut agglutinin and cone opsin–specific antibodies. Results. Cone degeneration started centrally and spread ventrally, with cells losing cone-opsin staining before that for the PNA-lectin–positive cone sheath. Gene therapy starting at P14 resulted in almost wild-type M- and S-cone function and morphology. Delaying gene-replacement rescued the remaining M-cones, and most important, more M-cone opsin–positive cells were identified than were present at the onset of gene therapy, suggesting that opsin expression could be reinitiated in cells with cone sheaths. Conclusions. The results support and extend those of the previous study that gene therapy can stop early cone degeneration, and, more important, they provide proof that delayed treatment can restore the function and morphology of the remaining cones. These results have important implications for the ongoing LCA2 clinical trials. PMID:21169527

  15. Quantitation of glandular gastric changes in rats given a proton pump inhibitor for 3 months with emphasis on sampling scheme selection.

    PubMed

    White, S L; Smith, W C; Fisher, L F; Gatlin, C L; Hanasono, G K; Jordan, W H

    1998-01-01

    Proton pump inhibitors and H2-receptor antagonists suppress gastric acid secretion and secondarily induce hypergastrinemia. Sustained hypergastrinemia has a trophic effect on stomach fundic mucosa, including enterochromaffin-like (ECL) cell hypertrophy and hyperplasia. Histomorphometric quantitation of the pharmacologic gastric effects was conducted on 10 male and 10 female rats treated orally with LY307640 sodium, a proton pump inhibitor, at daily doses of 25, 60, 130, or 300 mg/kg for 3 mo. Histologic sections of glandular stomach, stained for chromogranin A, were evaluated by image analysis to determine stomach mucosal thickness, mucosal and nonmucosal (submucosa and muscularis) area, gastric glandular area, ECL cell number/area and cross-sectional area. Total mucosal and nonmucosal tissue volumes per animal were derived from glandular stomach volumetric and area data. Daily oral doses of compound LY307640 sodium caused slight to moderate dose-related mucosal hypertrophy and ECL cell hypertrophy and hyperplasia in all treatment groups as compared with controls. All observed effects were prominent in both sexes but were generally greater in females. The morphometric sampling schemes were explored to optimize the data collection efficiency for future studies. A comparison between the sampling schemes used in this study and alternative schemes was conducted by estimating the probability of detecting a specific percentage of change between the male control and high-dose groups based on Tukey's trend test. The sampling scheme analysis indicated that mucosal thickness and mass had been oversampled. ECL cell density quantitation efficiency would have been increased by sampling the basal mucosa only for short-term studies. The ECL cell size sampling scheme was deemed appropriate for this type of study.

  16. 9 CFR 206.3 - Monthly report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... will be available on the Internet on the GIPSA Web site (http://www.usda.gov/gipsa/) and at USDA GIPSA... GIPSA through the Internet on the GIPSA Web site (http://www.usda.gov/gipsa/) or at USDA GIPSA, Suite... business day of each month. The monthly reports will be available on the Internet on the GIPSA Web...

  17. 9 CFR 206.3 - Monthly report.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... capacity, alone or in combination with other plants, specified in the definition of packer. (b) When is the... slaughtering capacity, alone or in combination with other plants specified in the definition of packer in § 206... reported on Form P&SP-341, which will be available on the Internet on the GIPSA Web site...

  18. 9 CFR 206.3 - Monthly report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... capacity, alone or in combination with other plants, specified in the definition of packer. (b) When is the... slaughtering capacity, alone or in combination with other plants specified in the definition of packer in § 206... reported on Form P&SP-341, which will be available on the Internet on the GIPSA Web site...

  19. 9 CFR 206.3 - Monthly report.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... capacity, alone or in combination with other plants, specified in the definition of packer. (b) When is the... slaughtering capacity, alone or in combination with other plants specified in the definition of packer in § 206... reported on Form P&SP-341, which will be available on the Internet on the GIPSA Web site...

  20. A BCR-ABL1 cutoff of 1.5% at 3 months, determined by the GeneXpert system, predicts an optimal response in patients with chronic myeloid leukemia

    PubMed Central

    García-Gutiérrez, Valentín; Gómez-Casares, María T.; Puerta, José M.; Alonso-Domínguez, Juan M.; Osorio, Santiago; Hernández-Boluda, Juan C.; Collado, Rosa; Ramírez, María J.; Ibáñez, Fátima; Martín, María L.; Rodríguez-Gambarte, Juan D.; Martínez-Laperche, Carolina; Gómez, Montse; Fiallo, Dolly V.; Redondo, Sara; Rodríguez, Alicia; Ruiz-Nuño, Concepción; Steegmann, Juan L.

    2017-01-01

    In chronic myeloid leukemia (CML) patients, 3-month BCR-ABL1 levels have consistently been correlated with further outcomes. Monitoring molecular responses in CML using the GeneXpert (Cepheid) platform has shown an optimal correlation with standardized RQ-PCR (IS) when measuring BCR-ABL1 levels lower than 10%, as it is not accurate for values over 10%. The aim of the present study was to determine the predictive molecular value at three months on different outcome variables using the Xpert BCR-ABL1 MonitorTM assay (Xpert BCR-ABL1). We monitored 125 newly diagnosed consecutive CML patients in the chronic phase (CML-CP) using an automated method: Xpert BCR-ABL1. Only 5% of patients did not achieve an optimal response at 3 months, and the 10% BCR-ABL1 cutoff defined by RQ-PCR (IS) methods was unable to identify significant differences in the probabilities of achieving a complete cytogenetic response (CCyR) (50% vs. 87%, p = 0.1) or a major molecular response (MMR) (60% vs. 80%, p = 0.29) by 12 months. In contrast, a cutoff of 1.5% more accurately identified differences in the probabilities of achieving CCyR (98% vs. 54%, p<0.001) and MMR (88% vs. 56%, p<0.001) by 12 months, as well as probabilities of treatment changes (p = 0.005). Therefore, when using the Xpert BCR-ABL1 assay, a cutoff of 1.5% at 3 months could with high probability identify patients able to achieve an optimal response at 12 months. PMID:28278193

  1. A BCR-ABL1 cutoff of 1.5% at 3 months, determined by the GeneXpert system, predicts an optimal response in patients with chronic myeloid leukemia.

    PubMed

    García-Gutiérrez, Valentín; Gómez-Casares, María T; Puerta, José M; Alonso-Domínguez, Juan M; Osorio, Santiago; Hernández-Boluda, Juan C; Collado, Rosa; Ramírez, María J; Ibáñez, Fátima; Martín, María L; Rodríguez-Gambarte, Juan D; Martínez-Laperche, Carolina; Gómez, Montse; Fiallo, Dolly V; Redondo, Sara; Rodríguez, Alicia; Ruiz-Nuño, Concepción; Steegmann, Juan L; Jiménez-Velasco, Antonio

    2017-01-01

    In chronic myeloid leukemia (CML) patients, 3-month BCR-ABL1 levels have consistently been correlated with further outcomes. Monitoring molecular responses in CML using the GeneXpert (Cepheid) platform has shown an optimal correlation with standardized RQ-PCR (IS) when measuring BCR-ABL1 levels lower than 10%, as it is not accurate for values over 10%. The aim of the present study was to determine the predictive molecular value at three months on different outcome variables using the Xpert BCR-ABL1 MonitorTM assay (Xpert BCR-ABL1). We monitored 125 newly diagnosed consecutive CML patients in the chronic phase (CML-CP) using an automated method: Xpert BCR-ABL1. Only 5% of patients did not achieve an optimal response at 3 months, and the 10% BCR-ABL1 cutoff defined by RQ-PCR (IS) methods was unable to identify significant differences in the probabilities of achieving a complete cytogenetic response (CCyR) (50% vs. 87%, p = 0.1) or a major molecular response (MMR) (60% vs. 80%, p = 0.29) by 12 months. In contrast, a cutoff of 1.5% more accurately identified differences in the probabilities of achieving CCyR (98% vs. 54%, p<0.001) and MMR (88% vs. 56%, p<0.001) by 12 months, as well as probabilities of treatment changes (p = 0.005). Therefore, when using the Xpert BCR-ABL1 assay, a cutoff of 1.5% at 3 months could with high probability identify patients able to achieve an optimal response at 12 months.

  2. Submillimeter Wave Astronomy Satellite Observations of Comet 9P/Tempel 1

    NASA Astrophysics Data System (ADS)

    Bensch, F.; Melnick, G. J.; Neufeld, D. A.; Harwit, M.; Snell, R. L.; Patten, B. M.; Tolls, V.

    We present observations of the 1_{10}-1_{01} ortho-water ground-state rotational transition in comet 9P/Tempel 1 made with the NASA Submillimeter Wave Astronomy Satellite (SWAS). The SWAS monitoring covered a 3-month period from June to August 2005 and included observations of the comet's activity during the collision of the Deep Impact spacecraft with the nucleus on 4 July 2005. No excess emission from the material ejected by the impactor was detected and we derive an upper limit of 1.8× 10^7 kg on the vaporized water ice. However, the water production rate of the comet shows large natural variations of up to a factor of three throughout the 3-month monitoring period. The total amount of water vaporized between 5 June and 1 September 2005 is 4.5× 1034 molecules (˜ 1.3× 10^9 kg) and we estimate that 9P/Tempel 1 has lost as much as N˜ 1035 molecules during its 2005 apparition.

  3. The impact of Mount Etna sulfur emissions on the atmospheric composition and aerosol properties in the central Mediterranean: A statistical analysis over the period 2000-2013 based on observations and Lagrangian modelling

    NASA Astrophysics Data System (ADS)

    Sellitto, Pasquale; Zanetel, Claudia; di Sarra, Alcide; Salerno, Giuseppe; Tapparo, Andrea; Meloni, Daniela; Pace, Giandomenico; Caltabiano, Tommaso; Briole, Pierre; Legras, Bernard

    2017-01-01

    The emission of gases and aerosols due to volcanic activity may impact significantly atmospheric composition, cloud occurrence and properties, and the regional and global climate. While the effects of strong explosive (stratospheric) eruptions are relatively well known, limited information on the impacts of small to moderate volcanic activities, including passive degassing, is available. In this paper, the downwind impact of Mount Etna's sulfur emissions on the central Mediterranean is investigated on a statistical basis over the period 2000-2013 using: (a) daily sulfur dioxid