Science.gov

Sample records for 3-q quarterly financial

  1. 18 CFR 260.300 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 260.300 Section 260... ENERGY APPROVED FORMS, NATURAL GAS ACT STATEMENTS AND REPORTS (SCHEDULES) § 260.300 FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas companies. (a)...

  2. 18 CFR 260.300 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 260.300 Section 260... ENERGY APPROVED FORMS, NATURAL GAS ACT STATEMENTS AND REPORTS (SCHEDULES) § 260.300 FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas companies. (a)...

  3. 18 CFR 260.300 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 260.300 Section 260... ENERGY APPROVED FORMS, NATURAL GAS ACT STATEMENTS AND REPORTS (SCHEDULES) § 260.300 FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas companies. (a)...

  4. 18 CFR 260.300 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 260.300 Section 260... ENERGY APPROVED FORMS, NATURAL GAS ACT STATEMENTS AND REPORTS (SCHEDULES) § 260.300 FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas companies. (a)...

  5. 18 CFR 260.300 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 260.300 Section 260... ENERGY APPROVED FORMS, NATURAL GAS ACT STATEMENTS AND REPORTS (SCHEDULES) § 260.300 FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas companies. (a)...

  6. 18 CFR 141.400 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 141.400 Section 141..., licensees, and natural gas companies. (a) Prescription. The quarterly report of electric utilities, licensees, and natural gas companies, designated as FERC Form No. 3-Q, is prescribed for the...

  7. 18 CFR 141.400 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 141.400 Section 141..., licensees, and natural gas companies. (a) Prescription. The quarterly report of electric utilities, licensees, and natural gas companies, designated as FERC Form No. 3-Q, is prescribed for the...

  8. 18 CFR 141.400 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 141.400 Section 141..., licensees, and natural gas companies. (a) Prescription. The quarterly report of electric utilities, licensees, and natural gas companies, designated as FERC Form No. 3-Q, is prescribed for the...

  9. 18 CFR 141.400 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 141.400 Section 141..., licensees, and natural gas companies. (a) Prescription. The quarterly report of electric utilities, licensees, and natural gas companies, designated as FERC Form No. 3-Q, is prescribed for the...

  10. 18 CFR 141.400 - FERC Form No. 3-Q, Quarterly financial report of electric utilities, licensees, and natural gas...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., Quarterly financial report of electric utilities, licensees, and natural gas companies. 141.400 Section 141..., licensees, and natural gas companies. (a) Prescription. The quarterly report of electric utilities, licensees, and natural gas companies, designated as FERC Form No. 3-Q, is prescribed for the...

  11. US energy industry financial developments, 1993 second quarter

    SciTech Connect

    Not Available

    1993-09-29

    US Energy Industry Financial Developments, 1993 Second Quarter provides information on the financial performance of energy companies during the most recent reporting period. The data are taken from public sources such as the Wall Street Journal, Energy Information Administration publications, corporate press releases, and other public sources. Based on information provided in 1993 second quarter financial disclosures, net income for 114 petroleum companies--including 19 majors--rose 33 percent between the second quarter of 1992 and the second quarter of 1993. Both upstream (oil and gas exploration, development and production) operations and downstream (petroleum refining, marketing, and transport) contributed to the improved financial Performance of petroleum companies consolidated operations. Rate-regulated industries also showed positive income growth between the second quarter of 1992 and the second quarter of 1993 due to higher natural gas prices and increased electricity consumption.

  12. US energy industry financial developments, 1993 third quarter

    SciTech Connect

    Not Available

    1993-12-01

    Based on information provided in 1993 third quarter financial disclosures, the average net income for 112 petroleum companies -- including 18 majors -- rose 13 percent between the third quarter of 1992 and the third quarter of 1993. The gain in overall petroleum income was derived from increases in refined product consumption and margins, which improved the profitability of downstream petroleum (refining, marketing and transport) operations. A 17-percent decline in crude oil prices led to reduced income for upstream (oil and gas exploration, development and production) operations. A 16-percent rise in natural gas wellhead prices only partially offset the negative effects of low crude oil prices. Electric utilities also reported improved financial results for the third quarter of 1993 as hotter summer temperatures relative to the year-earlier quarter helped boost air conditioning demand and overall electricity usage. The following points highlight third-quarter energy industry financial developments: (1) Refined product demand and margins lift downstream earnings. Petroleum product consumption rose 2 percent between the third quarter of 1992 and the third quarter of 1993. Although petroleum product prices declined in the most recent reporting period, they did not decline as much as crude oil input prices. As a consequence, refined product margins widened. (2) Lower crude oil prices reduce upstream earnings. Crude oil prices fell 17 percent between the third quarter of 1992 and the third quarter of 1993 leading to a substantial reduction in income for the major petroleum companies` upstream operations. (3) Drilling income rises with increased North American exploratory activity.

  13. US Energy Industry Financial Developments, 1993 fourth quarter, April 1994

    SciTech Connect

    Not Available

    1994-04-14

    This report traces key financial trends in the US energy industry for the fourth quarter of 1993. Financial data (only available for publicly-traded US companies) are included in two broad groups -- fossil fuel production and rate-regulated electric utilities. All financial data are taken from public sources such as energy industry corporate reports and press releases, energy trade publications, and The Wall Street Journal`s Earnings Digest; return on equity is calculated from data available from Standard and Poor`s Compustat data service. Since several major petroleum companies disclose their income by lines of business and geographic area, these data are also presented in this report. Although the disaggregated income concept varies by company and is not strictly comparable to corporate income, relative movements in income by lines of business and geographic area are summarized as useful indicators of short-term changes in the underlying profitability of these operations. Based on information provided in 1993 fourth quarter financial disclosures, the net income for 82 petroleum companies -- including 18 majors -- was unchanged between the fourth quarter of 1992 and the fourth quarter of 1993. An 18-percent decline in crude oil prices resulted in a deterioration of the performance of upstream (oil and gas production) petroleum companies during the final quarter of 1993. However, prices for refined products fell much less than the price of crude oil, resulting in higher refined product margins and downstream (refining, marketing and transport) petroleum earnings. An increase in refined product demand also contributed to the rise in downstream income.

  14. US energy industry financial developments, First quarter 1995

    SciTech Connect

    1995-06-19

    This report traces key developments in US energy companies` financial performance for the first quarter of 1995. Financial data (only available for publicly-traded US companies) are included in two broad groups -- fossil fuel production and rate-regulated utilities. All financial data are taken from public sources such as corporate reports and press releases, energy trade publications, and The Wall Street Journal`s Earnings Digest. Return on equity is calculated from data available from Standard and Poor`s Compustat data service. Since several major petroleum companies disclose their income by lines of business and geographic area, these data are also presented in this report. Although the disaggregated income concept varies by company and is not strictly comparable to corporate income, relative movements in income by lines of business and geographic area are summarized as useful indicators of short-term changes in the underlying profitability of these operations.

  15. US energy industry financial developments, 1994 first quarter

    SciTech Connect

    Not Available

    1994-06-23

    This report traces key financial trends in the US energy industry for the first quarter of 1994. Financial data (only available for publicly-traded US companies) are included in two broad groups -- fossil fuel production and rate-regulated electric utilities. All financial data are taken from public sources such as energy industry corporate reports and press releases, energy trade publications, and The Wall Street Journal`s, Earnings Digest. Return on equity is calculated from data available from Standard and Poor`s Compustat data service. Since several major petroleum companies disclose their income by lines of business and geographic area. These data are also presented in this report. Although the disaggregated income concept varies by company and is not strictly comparable to corporate income, relative movements in income by lines of business and geographic area are summarized as useful indicators of short-term changes in the underlying profitability of these operations.

  16. 77 FR 27021 - Proposed Information Collection; Comment Request; Quarterly Survey of Financial Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-08

    ... INFORMATION: I. Abstract Form BE-185, Quarterly Survey of Financial Services Transactions between U.S... Bureau of Economic Analysis Proposed Information Collection; Comment Request; Quarterly Survey of Financial Services Transactions Between U.S. Financial Services Providers and Foreign Persons AGENCY:...

  17. 13 CFR 107.1220 - Requirement for Licensee to file quarterly financial statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... quarterly financial statements. 107.1220 Section 107.1220 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES SBA Financial Assistance for Licensees (Leverage) Conditional... financial statements. As long as any part of SBA's Leverage commitment is outstanding, you must give SBA...

  18. 78 FR 5166 - BE-185: Quarterly Survey of Financial Services Transactions Between U.S. Financial Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... Bureau of Economic Analysis XRIN 0691-XC009 BE-185: Quarterly Survey of Financial Services Transactions Between U.S. Financial Services Providers and Foreign Persons AGENCY: Bureau of Economic Analysis... Analysis (BEA), Department of Commerce, is informing the public that it is conducting the mandatory...

  19. US energy industry financial developments, 1993 first quarter

    SciTech Connect

    Not Available

    1993-06-25

    Net income for 259 energy companies-- including, 20 major US petroleum companies-- rose 38 percent between the first quarter of 1992 and the first quarter of 1993. An increased level of economic activity, along with colder weather, helped lift the demand for natural gas. crude oil, coal, and electricity. The sharp rise in the domestic price of natural gas at the wellhead relative to the year-ago quarter was the most significant development in US energy during the first quarter. As a consequence of higher natural gas prices, the upstream segment of the petroleum industry reported large gains in income, while downstream income rose due to higher refined product demand. Increased economic activity and higher weather-related natural gas demand also led to improvements in income for the rate-regulated energy segment. However, declining domestic oil production continued to restrain upstream petroleum industry earnings growth, despite a moderate rise in crude oil prices.

  20. 78 FR 76241 - Rescission of Quarterly Financial Reporting Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-17

    ... Regulatory Review,'' 76 FR 3821 (Jan. 21, 2011), which required agencies, among other things, to prepare..., among other things, to prepare plans for reviewing existing rules. The rule eliminates the quarterly.... Table ES-1 displays the average annual net costs and benefits of the rule. Table ES-1--Estimated...

  1. 78 FR 31475 - Rescission of Quarterly Financial Reporting Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... year is 4 x 27/60 = 1.8 hours. Multiplying this figure by the 110 carriers that file quarterly reports... regarding our public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316). Executive... States Code (U.S.C.) requires certain for-hire motor carriers of property and household goods to...

  2. 77 FR 38211 - Rescission of Quarterly Financial Reporting Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... Federal Register (73 FR 3316). II. Regulatory Information FMCSA publishes this direct final rule under 49... Financial Reporting Requirements AGENCY: Federal Motor Carrier Safety Administration, DOT. ACTION: Direct final rule. SUMMARY: By direct final rule, the Federal Motor Carrier Safety Administration...

  3. 77 FR 51705 - Rescission of Quarterly Financial Reporting Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... reporting requirements for Form QFR and Form MP-1. DATES: The direct final rule published at 77 FR 38211... public dockets in the January 17, 2008 issue of the Federal Register (73 FR 3316). II. Background On June... Financial Reporting Requirements AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT....

  4. Novel features of 3q29 deletion syndrome: Results from the 3q29 registry

    PubMed Central

    Glassford, Megan R.; Rosenfeld, Jill A.; Freedman, Alexa A.; Zwick, Michael E.

    2016-01-01

    3q29 deletion syndrome is caused by a recurrent, typically de novo heterozygous 1.6 Mb deletion, but because incidence of the deletion is rare (1 in 30,000 births) the phenotype is not well described. To characterize the range of phenotypic manifestations associated with 3q29 deletion syndrome, we have developed an online registry (3q29deletion.org) for ascertainment of study subjects and phenotypic data collection via Internet‐based survey instruments. We report here on data collected during the first 18 months of registry operation, from 44 patients. This is the largest cohort of 3q29 deletion carriers ever assembled and surveyed in a systematic way. Our data reveal that 28% of registry participants report neuropsychiatric phenotypes, including anxiety disorder, panic attacks, depression, bipolar disorder, and schizophrenia. Other novel findings include a high prevalence (64%) of feeding problems in infancy and reduced weight at birth for 3q29 deletion carriers (average reduction 13.9 oz (394 g), adjusted for gestational age and sex, P = 6.5e‐07). We further report on the frequency of heart defects, autism, recurrent ear infections, gastrointestinal phenotypes, and dental phenotypes, among others. We also report on the expected timing of delayed developmental milestones. This is the most comprehensive description of the 3q29 deletion phenotype to date. These results are clinically actionable toward improving patient care for 3q29 deletion carriers, and can guide the expectations of physicians and parents. These data also demonstrate the value of patient‐reported outcomes to reveal the full phenotypic spectrum of rare genomic disorders. © 2016 The Authors. American Journal of Medical Genetics Part A Published by Wiley Periodicals, Inc. PMID:26738761

  5. Performance Plan: Progress Report 4th Quarter Fiscal Year 2000. Student Financial Assistance.

    ERIC Educational Resources Information Center

    Office of Student Financial Assistance (ED), Washington, DC.

    This is the final report on the fiscal year of Student Financial Assistance (SFA). It reports on progress toward three objectives: (1) customer satisfaction; (2) reducing the overall cost of delivering student aid; and (3) employee satisfaction. Of the planned projects, SFA completed all but three. One was postponed, one was dropped as not cost…

  6. 77 FR 2510 - Proposed Information Collection; Comment Request; Quarterly Financial Report

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-18

    ... current collection includes the Manufacturing, Mining, Wholesale Trade, Retail Trade, Information, and... provides financial data essential to the estimation of key Government measures of national economic performance. The importance of this data collection is reflected by the granting of specific authority...

  7. Adult expression of a 3q13.31 microdeletion

    PubMed Central

    2014-01-01

    Background The emerging 3q13.31 microdeletion syndrome appears to encompass diverse neurodevelopmental conditions. However, the 3q13.31 deletion is rare and few adult cases have yet been reported. We examined a cohort with schizophrenia (n = 459) and adult control subjects (n = 26,826) using high-resolution microarray technology for deletions and duplications at the 3q13.31 locus. Results We report on the extended adult phenotype associated with a 3q13.31 microdeletion in a 41-year-old male proband with schizophrenia and a nonverbal learning disability. He was noted to have a speech impairment, delayed motor skills, and other features consistent with the 3q13.31 microdeletion syndrome. The 2.06 Mb deletion overlapped two microRNAs and seven RefSeq genes, including GAP43, LSAMP, DRD3, and ZBTB20. No overlapping 3q13.31 deletions or duplications were identified in control subjects. Conclusions Later-onset conditions like schizophrenia are increasingly associated with rare copy number variations and associated genomic disorders like the 3q13.31 microdeletion syndrome. Detailed phenotype information across the lifespan facilitates genotype-phenotype correlations, accurate genetic counselling, and anticipatory care. PMID:24650298

  8. Blepharophimosis syndrome (BPES) is linked to chromosome 3q

    SciTech Connect

    Bradles, K.; Reimer, R.; Lessner, A.

    1994-09-01

    Blepharophimosis syndrome (BPES, blepharophimosis eyelid syndrome) is a distinctive congenital eyelid malformation which can occur sporadically or inherited in an autosomal dominant fashion. Previous reports have described associated chromosome 3q abnormalities. We ascertained two small autosomal dominant families with BPES and tested for linkage with 17 polymorphic markers on 3q. Multipoint analysis generated a maximum LOD score of 3.23 centered around markers RHO, ACPP and D3S1238. No evidence of genetic heterogeneity was observed. The defective gene responsible for BPES is located on 3q.

  9. U.S. Department of Energy Naval Petroleum Reserve Number 1 quarterly financial statements, March 31, 1997 and 1996

    SciTech Connect

    1997-04-17

    The report presents the results of the independent certified public accountants` review of the Department of Energy`s Naval Petroleum Reserve Number 1 interim financial statements as of March 31, 1997 and 1996. The review was done in accordance with Statements on Standards for Accounting and Review Services issued by the American Institute of Certified Public Accountants. A review of interim financial statements consist principally of inquires of NPR-1 personnel and analytical procedures applied to financial data. It is substantially less in scope than an audit in accordance with generally accepted auditing standards, the objective of which is the expression of an opinion regarding the financial statements taken as a whole. Accordingly, the certified public accountants do not express such an opinion. The auditors have stated that, except for the omission of certain disclosures, they are not aware of any material modifications that should be made to the financial statements in order for them to be in conformity with the other comprehensive basis of accounting described in Note 1 to the financial statements.

  10. U.S. Department of Energy Naval Petroleum Reserve Number 1 quarterly financial statements, December 31, 1996 and 1995

    SciTech Connect

    1997-03-18

    The report presents the results of the independent certified public accountants` review of the Department of Energy`s Naval Petroleum Reserve Number 1 interim financial statements as of December 31, 1996 and 1995. The review was done in accordance with Statements on Standards for Accounting and Review Services issued by the American Institute of Certified Public Accountants. A review of interim financial statements consists principally of inquiries of NPR-1 personnel and analytical procedures applied to financial data. It is substantially less in scope than an audit in accordance with generally accepted auditing standards, the objective of which is the expression of an opinion regarding the financial statements take as a whole. Accordingly, the certified public accountants do not express such an opinion. The auditors have stated that, except for the omission of certain disclosures, they are not aware of any material modifications that should be made to the financial statements in order for them to be in conformity with the other comprehensive basis of accounting described in Note 1 to the financial statements.

  11. Microdeletions of 3q29 Confer High Risk for Schizophrenia

    PubMed Central

    Mulle, Jennifer Gladys; Dodd, Anne F.; McGrath, John A.; Wolyniec, Paula S.; Mitchell, Adele A.; Shetty, Amol C.; Sobreira, Nara L.; Valle, David; Rudd, M. Katharine; Satten, Glen; Cutler, David J.; Pulver, Ann E.; Warren, Stephen T.

    2010-01-01

    Schizophrenia (SZ) is a severe psychiatric illness that affects ∼1% of the population and has a strong genetic underpinning. Recently, genome-wide analysis of copy-number variation (CNV) has implicated rare and de novo events as important in SZ. Here, we report a genome-wide analysis of 245 SZ cases and 490 controls, all of Ashkenazi Jewish descent. Because many studies have found an excess burden of large, rare deletions in cases, we limited our analysis to deletions over 500 kb in size. We observed seven large, rare deletions in cases, with 57% of these being de novo. We focused on one 836 kb de novo deletion at chromosome 3q29 that falls within a 1.3–1.6 Mb deletion previously identified in children with intellectual disability (ID) and autism, because increasing evidence suggests an overlap of specific rare copy-number variants (CNVs) between autism and SZ. By combining our data with prior CNV studies of SZ and analysis of the data of the Genetic Association Information Network (GAIN), we identified six 3q29 deletions among 7545 schizophrenic subjects and one among 39,748 controls, resulting in a statistically significant association with SZ (p = 0.02) and an odds ratio estimate of 17 (95% confidence interval: 1.36–1198.4). Moreover, this 3q29 deletion region contains two linkage peaks from prior SZ family studies, and the minimal deletion interval implicates 20 annotated genes, including PAK2 and DLG1, both paralogous to X-linked ID genes and now strong candidates for SZ susceptibility. PMID:20691406

  12. 3Q120 Low Gradient Behaviour-Companion Report

    SciTech Connect

    Wehmann, A.

    1985-10-01

    Three 3Q120 magnets--representative of those in the AP 1 line--have been measured with a harmonics probe at MDTF at both low (0-48 A) and high (to >= 400 A). The intent of the measurements was to learn their behavior at the low gradients necessary to transport 8 Gev antiprotons back through the AP 1 line for injection into the Main Ring. This paper describes some aspects of the measurements that were not included in the main paper, in order to keep the size of the main report reasonably small. It includes as Appendix I a chronology of the measurements made and significant changes made to the measurement apparatus and analysis programs.

  13. Validity of three screening questions (3Q/TMD) in relation to the DC/TMD.

    PubMed

    Lövgren, A; Visscher, C M; Häggman-Henrikson, B; Lobbezoo, F; Marklund, S; Wänman, A

    2016-10-01

    Temporomandibular disorders (TMD) are common but seem to be largely undetected within general dental care. To improve dentists' awareness of these symptoms, three screening questions (3Q/TMD) have been introduced. Our aim was to validate 3Q/TMD in relation to the diagnostic criteria for TMD (DC/TMD), while taking into account the severity level of the symptoms. The study population consisted of 7831 individuals 20-69 years old, who had their routine dental check-up at the Public Dental Health Service in Västerbotten, Sweden. All patients answered a health declaration, including the 3Q/TMD regarding frequent temporomandibular pain, pain on movement and catching/locking of the jaw. All 3Q-positives (at least one affirmative) were invited for examination in randomised order. For each 3Q-positive, a matched 3Q-negative was invited. In total, 152 3Q-positives and 148 3Q-negatives participated. At examination, participants answered 3Q/TMD a second time, before they were examined and diagnosed according to DC/TMD. To determine symptom's severity, the Graded Chronic Pain Scale and Jaw Functional Limitation Scale-20 (JFLS-20) were used. In total, 74% of 3Q-positives and 16% of 3Q-negatives met the criteria for DC/TMD pain or dysfunction (disc displacements with reduction and degenerative joint disorder were excluded). Fifty-five per cent of 3Q-positives had a TMD diagnosis and CPI score ≥3 or a JFLS-20 score ≥5, compared to 4% of 3Q-negatives. The results show that the 3Q/TMD is an applicable, cost-effective and valid tool for screening a general adult population to recognise patients in need of further TMD examination and management. PMID:27573533

  14. Complex chromosomal rearrangements leading to MECOM overexpression are recurrent in myeloid malignancies with various 3q abnormalities.

    PubMed

    Baldazzi, Carmen; Luatti, Simona; Zuffa, Elisa; Papayannidis, Cristina; Ottaviani, Emanuela; Marzocchi, Giulia; Ameli, Gaia; Bardi, Maria Antonella; Bonaldi, Laura; Paolini, Rossella; Gurrieri, Carmela; Rigolin, Gian Matteo; Cuneo, Antonio; Martinelli, Giovanni; Cavo, Michele; Testoni, Nicoletta

    2016-04-01

    Chromosomal rearrangements involving 3q26 are recurrent findings in myeloid malignancies leading to MECOM overexpression, which has been associated with a very poor prognosis. Other 3q abnormalities have been reported and cryptic MECOM rearrangements have been identified in some cases. By fluorescence in situ hybridization (FISH) analysis, we investigated 97 acute myeloid leukemia/myelodysplastic syndrome patients with various 3q abnormalities to determine the role and the frequency of the involvement of MECOM. We identified MECOM rearrangements in 51 patients, most of them showed 3q26 involvement by chromosome banding analysis (CBA): inv(3)/t(3;3) (n = 26) and other balanced 3q26 translocations (t(3q26)) (n = 15); the remaining cases (n = 10) showed various 3q abnormalities: five with balanced translocations involving 3q21 or 3q25; two with homogenously staining region (hsr) on 3q; and three with other various 3q abnormalities. Complex rearrangements with multiple breakpoints on 3q, masking 3q26 involvement, were identified in cases with 3q21/3q25 translocations. Furthermore, multiple breaks were observed in two cases with t(3q26), suggesting that complex rearrangement may also occur in apparently simple t(3q26). Intrachromosomal gene amplification was another mechanism leading to MECOM overexpression in two cases with hsr on 3q. In the last three cases, FISH analysis revealed 3q26 involvement that was missed by CBA because of metaphases' suboptimal quality. All cases with MECOM rearrangements showed overexpression by real-time quantitative PCR. Finally, MECOM rearrangements can occur in patients with 3q abnormalities even in the absence of specific 3q26 involvement, underlining that their frequency is underestimated. As MECOM rearrangement has been associated with very poor prognosis, its screening should be performed in patients with any 3q abnormalities.

  15. Complex chromosomal rearrangements leading to MECOM overexpression are recurrent in myeloid malignancies with various 3q abnormalities.

    PubMed

    Baldazzi, Carmen; Luatti, Simona; Zuffa, Elisa; Papayannidis, Cristina; Ottaviani, Emanuela; Marzocchi, Giulia; Ameli, Gaia; Bardi, Maria Antonella; Bonaldi, Laura; Paolini, Rossella; Gurrieri, Carmela; Rigolin, Gian Matteo; Cuneo, Antonio; Martinelli, Giovanni; Cavo, Michele; Testoni, Nicoletta

    2016-04-01

    Chromosomal rearrangements involving 3q26 are recurrent findings in myeloid malignancies leading to MECOM overexpression, which has been associated with a very poor prognosis. Other 3q abnormalities have been reported and cryptic MECOM rearrangements have been identified in some cases. By fluorescence in situ hybridization (FISH) analysis, we investigated 97 acute myeloid leukemia/myelodysplastic syndrome patients with various 3q abnormalities to determine the role and the frequency of the involvement of MECOM. We identified MECOM rearrangements in 51 patients, most of them showed 3q26 involvement by chromosome banding analysis (CBA): inv(3)/t(3;3) (n = 26) and other balanced 3q26 translocations (t(3q26)) (n = 15); the remaining cases (n = 10) showed various 3q abnormalities: five with balanced translocations involving 3q21 or 3q25; two with homogenously staining region (hsr) on 3q; and three with other various 3q abnormalities. Complex rearrangements with multiple breakpoints on 3q, masking 3q26 involvement, were identified in cases with 3q21/3q25 translocations. Furthermore, multiple breaks were observed in two cases with t(3q26), suggesting that complex rearrangement may also occur in apparently simple t(3q26). Intrachromosomal gene amplification was another mechanism leading to MECOM overexpression in two cases with hsr on 3q. In the last three cases, FISH analysis revealed 3q26 involvement that was missed by CBA because of metaphases' suboptimal quality. All cases with MECOM rearrangements showed overexpression by real-time quantitative PCR. Finally, MECOM rearrangements can occur in patients with 3q abnormalities even in the absence of specific 3q26 involvement, underlining that their frequency is underestimated. As MECOM rearrangement has been associated with very poor prognosis, its screening should be performed in patients with any 3q abnormalities. PMID:26815134

  16. HYDRAULIC CONDUCTIVITY OF SALTSTONE FORMULATED USING 1Q11, 2Q11 AND 3Q11 TANK 50 SLURRY SAMPLES

    SciTech Connect

    Reigel, M.; Nichols, R.

    2012-06-27

    As part of the Saltstone formulation work requested by Waste Solidification Engineering (WSE), Savannah River National Laboratory (SRNL) was tasked with preparing Saltstone samples for fresh property analysis and hydraulic conductivity measurements using actual Tank 50 salt solution rather than simulated salt solution. Samples of low level waste salt solution collected from Tank 50H during the first, second, and third quarters of 2011 were used to formulate the Saltstone samples. The salt solution was mixed with premix (45 wt % slag, 45 wt % fly ash, and 10 wt % cement), in a ratio consistent with facility operating conditions during the quarter of interest. The fresh properties (gel, set, bleed) of each mix were evaluated and compared to the recommended acceptance criteria for the Saltstone Production Facility. ASTM D5084-03, Method C was used to measure the hydraulic conductivity of the Saltstone samples. The hydraulic conductivity of Saltstone samples prepared from 1Q11 and 2Q11 samples of Tank 50H is 4.2E-9 cm/sec and 2.6E-9 cm/sec, respectively. Two additional 2Q11 and one 3Q11 sample were not successfully tested due to the inability to achieve stable readings during saturation and testing. The hydraulic conductivity of the samples made from Tank 50H salt solution compare well to samples prepared with simulated salt solution and cured under similar conditions (1.4E-9 - 4.9E-8 cm/sec).

  17. Azacitidine treatment for patients with myelodysplastic syndrome and acute myeloid leukemia with chromosome 3q abnormalities.

    PubMed

    Wanquet, Anne; Prebet, Thomas; Berthon, Céline; Sebert, Marie; Roux, Clémence; Kulasekararaj, Austin; Micol, Jean-Baptiste; Esterni, Benjamin; Itzykson, Raphael; Thepot, Sylvain; Recher, Christian; Delaunay, Jacques; Dreyfus, François; Mufti, Ghulam; Fenaux, Pierre; Vey, Norbert

    2015-10-01

    Acute Myeloid Leukemia (AML) and myelodysplasia (MDS) with chromosome 3q abnormalities have a dismal outcome either untreated or with conventional treatments. Azacitidine (AZA) is now considered as the standard of care in high-risk MDS and oligoblastic AML patients. The objective of this study was to evaluate the impact of azacitine treatment in this cytogenetic subgroup. We report here a multicentre retrospective study of 157 patients treated with AZA for AML/MDS with chromosome 3q abnormalities and 27 patients with isolated EVI-1 overexpression. Median age was 65 years, 40 patients (25%) had inv(3)(q21q26.2) or t(3;3)(q21;q26.2), 36 patients (23%) had other balanced 3q26 rearrangements, 8 patients (5%) had balanced 3q21 rearrangements and 73 patients (46%) had other 3q abnormalities. The overall response rate was 50% (29% CR). Median overall survival was 10.6 months. By multivariate analysis, patients with lower bone marrow blast counts, higher platelet counts, non-complex cytogenetics, and absence of prior treatment with intensive chemotherapy had a better outcome. 27 patients were allo-transplanted and achieved a 21-month median OS. Balanced 3q21 translocations were associated with a better response rate and overall survival. Outcome of patients with isolated EVI-1 overexpression was comparable to that of patients with chromosome 3q lesions. Thus, AML/MDS patients with 3q abnormalities appear to be a heterogeneous group in their response to AZA, and AZA may represent a suitable option in particular as a bridge to allogeneic transplantation.

  18. 3q26 Amplification Is an Effective Negative Triage Test for LSIL: A Historical Prospective Study

    PubMed Central

    Heitmann, Erica R.; Lankachandra, Kamani M.; Wall, Jeff; Harris, George D.; McKinney, Hollie J.; Jalali, G. Reza; Verma, Yogita; Kershnar, Eric; Kilpatrick, Michael W.; Tsipouras, Petros; Harper, Diane M.

    2012-01-01

    Background Women with low grade squamous intraepithelial lesions (LSIL) at cervical cancer screening are currently referred for further diagnostic work up despite 80% having no precancerous lesion. The primary purpose of this study is to measure the test characteristics of 3q26 chromosome gain (3q26 gain) as a host marker of carcinogenesis in women with LSIL. A negative triage test may allow these women to be followed by cytology alone without immediate referral to colposcopy. Methods and Findings A historical prospective study was designed to measure 3q26 gain from the archived liquid cytology specimens diagnosed as LSIL among women attending colposcopy between 2007 and 2009. 3q26 gain was assessed on the index liquid sample; and sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were measured at immediate triage and at 6–16 months after colposcopic biopsy. The sensitivity of 3q26 gain measured at immediate triage from automated and manually reviewed tests in 65 non-pregnant unique women was 70% (95% CI: 35, 93) with a NPV of 89% (95% CI: 78, 96). The sensitivity and NPV increased to 80% (95% CI: 28, 99) and 98% (95% CI: 87, 100), respectively, when only the automated method of detecting 3q26 gain was used. Conclusions 3q26 gain demonstrates high sensitivity and NPV as a negative triage test for women with LSIL, allowing possible guideline changes to routine surveillance instead of immediate colposcopy. Prospective studies are ongoing to establish the sensitivity, specificity, PPV and NPV of 3q26 gain for LSIL over time. PMID:22792164

  19. Cytogenetic, FISH and molecular characterization of 3q27/BCL-6 rearrangements in NHL

    SciTech Connect

    Wiodarska, I.; Styl, M.; Mecucci, C.

    1994-09-01

    Reciprocal translocations involving the chromosomal region 3q27 and one of the immunoglobulin loci at 14q32, 2p12 or 22q11 have been identified as the third most common type of chromosomal abnormality in Non Hodgkin`s lymphomas (NHLs), in addition to t(14;18) and t(8;14). These abnormalities appeared to be strongly associated with a diffuse, large cell subtype of B-cell NHL. Recently, a t(3;14) and t(3;22) have been cloned and a new transcriptional unit at 3q27, designated BCL-5, BCL-6 or LAZ3, has been identified. The gene appears to encode a new zinc finger protein with the putative function of a transcription factor. Rearrangements of the BCL-6 gene have been detected not only in cases with a typical t(3;14), t(2;3) and t(3;22), but also in a few NHL cases carrying 3q27 translocations not involving Ig genes. We report on nine B-NHL cases with a 3q27/BCL-6 rearrangement demonstrated by cytogenetic, FISH, and Southern analysis. Cytogenetic analysis complemented by FISH studies showed the presence of a classical t(3;14) or a t(3;22) in three cases and a variety of chromosomal aberrations involving the 3q27 locus in the remaining cases. Some of these translocations were not previously identified by conventional banding analysis. In three patients chromosome painting demonstrated involvement of both chromosome at the 3q24 band. We conclude: 3q27/BCL-6 rearrangements seem not to be restricted to diffuse large cell lymphoma. We here documented 3q27/BCL-6 abnormalities in Richter syndrome and follicular lymphomas. The variety of 3q27 aberrations at cytogenetic level suggests that, in addition to immunoglobulin genes, a number of other genes spreading over the human genome may deregulate BCL-6 in lymphomas. Chromosome painting is a powerful tool to demonstrate 3q27 abnormalities, not identified by conventional banding analysis.

  20. 12 CFR 620.11 - Content of quarterly report to shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Content of quarterly report to shareholders... SHAREHOLDERS Quarterly Report § 620.11 Content of quarterly report to shareholders. (a) General. The... shareholders, except that the financial statements included in the quarterly report may be condensed into...

  1. The emerging microduplication 3q13.31: Expanding the genotype-phenotype correlations of the reciprocal microdeletion 3q13.31 syndrome.

    PubMed

    Hervé, B; Fauvert, D; Dard, R; Roume, J; Cognard, S; Goidin, D; Lozach, F; Molina-Gomes, D; Vialard, F

    2016-09-01

    Microdeletion and microduplication syndromes are well-known causes of developmental delay and/or malformations of differing severity. It was recently reported that a microdeletion at the 3q13.31 locus is associated with a new syndrome combining developmental delay, postnatal overgrowth and dysmorphic features. However, the reciprocal microduplication has only been described in a few case reports displaying some clinical features of the microdeletion syndrome. Here, we report on a female infant with a 3.34 Mb microduplication of the 3q13.2q13.31 region inherited from her mother. The infant presented with severe intellectual disability, learning difficulties, intrauterine and postnatal growth retardation and skeletal particularities but no dysmorphic traits. This microduplication encompassed the previously described shortest region of overlap, which contains five genes (DRD3, ZNF80, TIGIT, MIR568 and ZBTB20). We reviewed the phenotypes described in the literature on microduplications and in the well-characterized 3q13.31 microdeletion syndrome. In agreement with the literature data, DRD3 and ZBTB20 appear to be strong candidate genes for neurodevelopmental defects and growth retardation. Lastly, we consider the putative mechanism of this rearrangement, which may involve a particular kind of nonallelic homologous recombination of human endogenous retrovirus elements. PMID:27568866

  2. Prenatal diagnosis of primary anophthalmia with a 3q27 interstitial deletion involving SOX2.

    PubMed

    Guichet, Agnès; Triau, Stéphane; Lépinard, Catherine; Esculapavit, Chantal; Biquard, Florence; Descamps, Philippe; Encha-Razavi, Férechté; Bonneau, Dominique

    2004-10-01

    We report an interstitial deletion of chromosome 3q26-q28 in a fetus in which anophthalmia had been detected prenatally. FISH analysis, using BAC clones encompassing the SOX2 locus, showed that SOX2 gene was involved in the chromosomal breakpoint of the deletion. This case confirms that haploinsufficiency for SOX2 plays a crucial role in human eye development and emphasizes the necessity of careful chromosomal analysis, including FISH analysis of the 3q region, in case of prenatal discovery of anophthalmia.

  3. Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers

    PubMed Central

    Hagerstrand, Daniel; Tong, Alexander; Schumacher, Steven E.; Ilic, Nina; Shen, Rhine R.; Cheung, Hiu Wing; Vazquez, Francisca; Shrestha, Yashaswi; Kim, So Young; Giacomelli, Andrew O.; Rosenbluh, Joseph; Schinzel, Anna C.; Spardy, Nicole A.; Barbie, David A.; Mermel, Craig H.; Weir, Barbara A.; Garraway, Levi A.; Tamayo, Pablo; Mesirov, Jill P.; Beroukhim, Rameen; Hahn, William C.

    2013-01-01

    3q26 is frequently amplified in several cancer types with a common amplified region containing 20 genes. To identify cancer driver genes in this region, we interrogated the function of each of these genes by loss- and gain-of-function genetic screens. Specifically, we found that TLOC1 (SEC62) was selectively required for the proliferation of cell lines with 3q26 amplification. Increased TLOC1 expression induced anchorage independent growth and a second 3q26 gene, SKIL (SNON), facilitated cell invasion in immortalized human mammary epithelial cells. Expression of both TLOC1 and SKIL induced subcutaneous tumor growth. Proteomic studies demonstrated that TLOC1 binds to DDX3X, which is essential for TLOC1-induced transformation and affected protein translation. SKIL induced invasion through up-regulation of SLUG (SNAI2) expression. Together, these studies identify TLOC1 and SKIL as driver genes at 3q26 and more broadly suggest that cooperating genes may be co-amplified in other regions with somatic copy number gain. PMID:23764425

  4. Mapping a gene for adult-onset primary open-angle glaucoma to chromosome 3q

    SciTech Connect

    Wirtz, M.K.; Samples, J.R.; Kramer, P.L.

    1997-02-01

    Glaucoma is the third-leading cause of blindness in the world, affecting >13.5 million people. Adult-on-set primary open-angle glaucoma (POAG) is the most common form of glaucoma in the United States. We present a family in which adult-onset POAG is inherited as an autosomal dominant trait. Twelve affected family members were identified from 44 at-risk individuals. The disease-causing gene was mapped to chromosome 3q21-24, with analysis of recombinant haplotypes suggesting a total inclusion region of 11.1 cM between markers D3S3637 and D3S1744. This is the first report of mapping of an adult-onset POAG gene to chromosome 3q, gene symbol GLC1C. 57 refs., 3 figs., 3 tabs.

  5. Clinical effects of iridectomy performed by laser YAG Nd+3 Q switch

    NASA Astrophysics Data System (ADS)

    Kecik, Tadeusz; Zydecki, Miroslaw

    1995-03-01

    Clinical effects of iridectomy performed by the use of laser Yag Nd+3-Q-switch on 38 patients treated for intra-ocular pressure increase were analyzed. In 32 cases primary glaucoma was diagnosed. In 11 cases secondary glaucoma was caused by pupil blocking. Pressure normalization was obtained in 27 cases (71%). In the remaining 11 patients pressure decreasing was acquired but at the same time administration of antiglaucoma medicines was indispensable. Time of observation took from 4 weeks to 3 years.

  6. The prostatic acid phosphatase (ACPP) gene is localized to human chromosome 3q21-q23

    SciTech Connect

    Li, S.S.L.; Sharief, F.S. )

    1993-09-01

    Human prostatic acid phosphatase (ACPP) has been used as a diagnostic marker for prostate cancer. It is synthesized under androgen regulation and secreted by the epithelial cells of the prostate gland. The authors have confirmed the previous assignment of the ACPP gene to chromosome 3 by probing a panel of 25 human-Chinese hamster somatic cell hybrids, and they have further localized the ACPP gene to chromosome 3q21-q23 by fluorescence in situ hybridization. 10 refs., 1 fig.

  7. The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy

    PubMed Central

    Heliö, Tiina; Jääskeläinen, Pertti; Laine, Mika; Hilvo, Mika; Nieminen, Markku S.; Laakso, Markku; Hyötyläinen, Tuulia; Orešič, Matej; Kuusisto, Johanna

    2015-01-01

    Aims Mutations in the cardiac myosin-binding protein C gene (MYBPC3) are the most common genetic cause of hypertrophic cardiomyopathy (HCM) worldwide. The molecular mechanisms leading to HCM are poorly understood. We investigated the metabolic profiles of mutation carriers with the HCM-causing MYBPC3-Q1061X mutation with and without left ventricular hypertrophy (LVH) and non-affected relatives, and the association of the metabolome to the echocardiographic parameters. Methods and Results 34 hypertrophic subjects carrying the MYBPC3-Q1061X mutation, 19 non-hypertrophic mutation carriers and 20 relatives with neither mutation nor hypertrophy were examined using comprehensive echocardiography. Plasma was analyzed for molecular lipids and polar metabolites using two metabolomics platforms. Concentrations of branched chain amino acids, triglycerides and ether phospholipids were increased in mutation carriers with hypertrophy as compared to controls and non-hypertrophic mutation carriers, and correlated with echocardiographic LVH and signs of diastolic and systolic dysfunction in subjects with the MYBPC3-Q1061X mutation. Conclusions Our study implicates the potential role of branched chain amino acids, triglycerides and ether phospholipids in HCM, as well as suggests an association of these metabolites with remodeling and dysfunction of the left ventricle. PMID:26267065

  8. 18 CFR 357.4 - FERC Form No. 6-Q, Quarterly report of oil pipeline companies.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., Quarterly report of oil pipeline companies. 357.4 Section 357.4 Conservation of Power and Water Resources... No. 6-Q, Quarterly report of oil pipeline companies. (a) Prescription. The quarterly financial report form of oil pipeline companies, designated as FERC Form No. 6-Q, is prescribed for the...

  9. 18 CFR 357.4 - FERC Form No. 6-Q, Quarterly report of oil pipeline companies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., Quarterly report of oil pipeline companies. 357.4 Section 357.4 Conservation of Power and Water Resources... No. 6-Q, Quarterly report of oil pipeline companies. (a) Prescription. The quarterly financial report form of oil pipeline companies, designated as FERC Form No. 6-Q, is prescribed for the...

  10. 18 CFR 357.4 - FERC Form No. 6-Q, Quarterly report of oil pipeline companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., Quarterly report of oil pipeline companies. 357.4 Section 357.4 Conservation of Power and Water Resources... No. 6-Q, Quarterly report of oil pipeline companies. (a) Prescription. The quarterly financial report form of oil pipeline companies, designated as FERC Form No. 6-Q, is prescribed for the...

  11. 18 CFR 357.4 - FERC Form No. 6-Q, Quarterly report of oil pipeline companies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., Quarterly report of oil pipeline companies. 357.4 Section 357.4 Conservation of Power and Water Resources... No. 6-Q, Quarterly report of oil pipeline companies. (a) Prescription. The quarterly financial report form of oil pipeline companies, designated as FERC Form No. 6-Q, is prescribed for the...

  12. 18 CFR 357.4 - FERC Form No. 6-Q, Quarterly report of oil pipeline companies.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., Quarterly report of oil pipeline companies. 357.4 Section 357.4 Conservation of Power and Water Resources... No. 6-Q, Quarterly report of oil pipeline companies. (a) Prescription. The quarterly financial report form of oil pipeline companies, designated as FERC Form No. 6-Q, is prescribed for the...

  13. 49 CFR 1152.37 - Financial status reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Financial status reports. 1152.37 Section 1152.37... Financial status reports. Within 30 days after the end of each quarter of the subsidy year, each carrier which is party to the financial assistance agreement shall submit to the subsidizer a Financial...

  14. Autosomal dominant retinitis pigmentosa: no evidence for nonallelic genetic heterogeneity on 3q.

    PubMed Central

    Kumar-Singh, R; Wang, H; Humphries, P; Farrar, G J

    1993-01-01

    Since the initial report of linkage of autosomal dominant retinitis pigmentosa (adRP) to the long arm of chromosome 3, several mutations in the gene encoding rhodopsin, which also maps to 3q, have been reported in adRP pedigrees. However, there has been some discussion as to the possibility of a second adRP locus on 3q. This suggestion has important diagnostic and research implications and must raise doubts about the usefulness of linked markers for reliable diagnosis of RP patients. In order to address this issue we have performed an admixture test (A-test) on 10 D3S47-linked adRP pedigrees and have found a likelihood ratio of heterogeneity versus homogeneity of 4.90. We performed a second A-test, combining the data from all families with known rhodopsin mutations. In this test we obtained a reduced likelihood ratio of heterogeneity versus homogeneity, of 1.0. On the basis of these statistical analyses we have found no significant support for two adRP loci on chromosome 3q. Furthermore, using 40 CEPH families, we have localized the rhodopsin gene to the D3S47-D3S20 interval, with a maximum lod score (Zm) of 20 and have found that the order qter-D3S47-rhodopsin-D3S20-cen is significantly more likely than any other order. In addition, we have mapped (Zm = 30) the microsatellite marker D3S621 relative to other loci in this region of the genome. PMID:8430695

  15. Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21.

    PubMed

    Christensen, Ulla; Møller-Larsen, Steffen; Nyegaard, Mette; Haagerup, Annette; Hedemand, Anne; Brasch-Andersen, Charlotte; Kruse, Torben A; Corydon, Thomas Juhl; Deleuran, Mette; Børglum, Anders D

    2009-10-01

    Atopic dermatitis (AD) is a common, itchy skin disease of complex inheritance characterized by dermal and epidermal inflammation. The heritability is considerable and well documented. To date, four genome scans have examined the AD phenotype, showing replicated linkage at 3p26-22, 3q13-21 and 18q11-21. Our previous AD scan showed evidence of linkage to loci at 3p and 18q, and furthermore at 4p15-14. In order to further investigate the genetic basis of AD, we collected and analysed a new Danish family sample consisting of 130 AD sib pair families (555 individuals including 295 children with AD). AD was diagnosed after clinical examination, AD severity was scored and specific IgE was determined. A linkage scan of chromosome 3, 4 and 18 was performed using 91 microsatellite markers. Linkage analyses were performed of dichotomous phenotypes and semi-quantitative traits including the AD severity score. We analysed the novel AD sample alone and together with the previously examined sample. AD severity showed a maximum Z-score of 3.7 at 4q22.1 suggesting the localization of a novel gene for AD severity. A maximum MOD score of 4.6 was obtained at 3p24 for the AD phenotype, providing the first significant linkage of AD at this locus. A maximum MLS score of 3.3 was obtained at 3q21 for IgE-associated AD, and evidence of linkage was also obtained at 3p22.2-21.31, 3q13, 4q35, and 18q12. The results presented should provide a firm basis for gene-targeting studies of AD and related disorders. PMID:19517137

  16. Liveborn with both partial trisomy of 3q and partial monosomy of 9p

    SciTech Connect

    Farren-Chavez, D.M.; Guzman, E.R.; Peters, T.L.

    1994-09-01

    A 32-year-old G{sub 3}P{sub 2002} Hispanic female presented at 14 weeks gestation for routine dating ultrasound. At that time ultrasonography revealed a septated cystic hygroma, omphalocele, bilateral talipes equinovarus, and hydrops. Amniocentesis was performed at 15 weeks and revealed a 46,XX,9p+ chromosome complement. The origin of the extra material on the terminal short arm of chromosome 9 could not be identified. Chromosome analysis was performed on the parents and the mother was found to carry the balanced translocation 46,XX,p(3;9)(q23;p13). Further analysis revealed that the fetus had inherited the derivative 9 chromosome. The fetus was therefore monosomic for 9p13-9pter and trisomic for 3q23-3pter. The patient chose to continue the pregnancy. Serial ultrasonography later demonstrated a sloping forehead, small nose, micrognathia, ventriculomegaly, possible VSD, micropenis, hypospadias, cryptorchidism and post-axial polydactyly of the hands. The fetus was delivered prematurely at 31 weeks and survived one hour. Post-mortem examination confirmed the ultrasound findings and revealed additional stigmata consistent with both 9p monosomy and 3q trisomy. A review of the literature indicates no previous report of both syndromes concurrently.

  17. Congenital thrombocytopenia in a neonate with an interstitial microdeletion of 3q26.2q26.31.

    PubMed

    Bouman, Arjan; Knegt, Lia; Gröschel, Stefan; Erpelinck, Claudia; Sanders, Mathijs; Delwel, Ruud; Kuijpers, Taco; Cobben, Jan Maarten

    2016-02-01

    Interstitial deletions encompassing the 3q26.2 region are rare. Only one case-report was published this far describing a patient with an interstitial deletion of 3q26.2 (involving the MDS1-EVI1 complex (MECOM)) and congenital thrombocytopenia. In this report we describe a case of a neonate with congenital thrombocytopenia and a constitutional 4.52 Mb deletion of 3q26.2q26.31 including TERC and the first 2 exons of MECOM, involving MDS1 but not EVI1. The deletion was demonstrated by array-CGH on lymphocytes. Our report confirms that congenital thrombocytopenia can be due to a constitutional deletion of 3q26.2 involving MECOM. We suggest that in case of unexplained neonatal thrombocytopenia, with even just slight facial dysmorphism, DNA microarray on peripheral blood should be considered early in the diagnostic work-up.

  18. Terminal deletion of the long arm of chromosome 3 [46,XX,del(3)(q27{r_arrow}qter)

    SciTech Connect

    Chitayat, D.; Babul, R.; Silver, M.M.

    1996-01-02

    We report on a terminal deletion of the long arm of chromosome 3[46,XX,del(3)(q27{r_arrow}qter)] in a female newborn infant who died 45 hours after delivery and had multiple congenital abnormalities including bilateral anophthalmia, congenital heart disease, and abnormal genitalia. The findings are compared to those of four previously reported cases with terminal de (3q). 8 refs., 4 figs., 1 tab.

  19. True 3q Chromosomal Amplification in Squamous Cell Lung Carcinoma by FISH and aCGH Molecular Analysis: Impact on Targeted Drugs

    PubMed Central

    Brunelli, Matteo; Bria, Emilio; Nottegar, Alessia; Cingarlini, Sara; Simionato, Francesca; Caliò, Anna; Eccher, Albino; Parolini, Claudia; Iannucci, Antonio; Gilioli, Eliana; Pedron, Serena; Massari, Francesco; Tortora, Giampaolo; Borze, Ioana; Knuutila, Sakari; Gobbo, Stefano; Santo, Antonio; Tondulli, Luca; Calabrò, Francesco; Martignoni, Guido; Chilosi, Marco

    2012-01-01

    Squamous lung carcinoma lacks specific “ad hoc” therapies. Amplification of chromosome 3q is the most common genomic aberration and this region harbours genes having role as novel targets for therapeutics. There is no standard definition on how to score and report 3q amplification. False versus true 3q chromosomal amplification in squamous cell lung carcinoma may have tremendous impact on trials involving drugs which target DNA zones mapping on 3q. Forty squamous lung carcinomas were analyzed by FISH to assess chromosome 3q amplification. aCGH was performed as gold-standard to avoid false positive amplifications. Three clustered patterns of fluorescent signals were observed. Eight cases out of 40 (20%) showed ≥8 3q signals. Twenty out of 40 (50%) showed from 3 to 7 signals. The remaining showed two fluorescent signals (30%). When corrected by whole chromosome 3 signals, only cases with ≥8 signals maintained a LSI 3q/CEP3 ratio >2. Only the cases showing 3q amplification by aCGH (+3q25.3−3q27.3) showed ≥8 fluorescent signals at FISH evidencing a 3q/3 ratio >2. The remaining cases showed flat genomic portrait at aCGH on chromosome 3. We concluded that: 1) absolute copy number of 3q chromosomal region may harbour false positive interpretation of 3q amplification in squamous cell carcinoma; 2) a case results truly “amplified for chromosome 3q” when showing ≥8 fluorescent 3q signals; 3) trials involving drugs targeting loci on chromosome 3q in squamous lung carcinoma therapy have to consider false versus true 3q chromosomal amplification. PMID:23236352

  20. Autozygosity Mapping of a Seckel Syndrome Locus to Chromosome 3q22.1-q24

    PubMed Central

    Goodship, Judith; Gill, Harinder; Carter, Joan; Jackson, Andrew; Splitt, Miranda; Wright, Michael

    2000-01-01

    Seckel syndrome (MIM 210600) is an autosomal recessive disorder of low birth weight, severe microcephaly, and dysmorphic facial appearance with receding forehead, prominent nose, and micrognathia. We have performed a genomic screen in two consanguineous families of Pakistani origin and found that the disorder segregates with markers between loci D3S1316 and D3S3710, which map to chromosome 3q22.1-q24. Analysis using HOMOZ/MAPMAKER gave a maximum LOD score of 8.72. All five affected individuals were homozygous for the same allele, for two adjacent polymorphic markers within the region segregating with the disease, narrowing the region to 12 cM. PMID:10889046

  1. Genotype-phenotype correlation in 13q13.3-q21.3 deletion.

    PubMed

    Tosca, Lucie; Brisset, Sophie; Petit, François M; Metay, Corinne; Latour, Stéphanie; Lautier, Benoît; Lebas, Axel; Druart, Luc; Picone, Olivier; Mas, Anne-Elisabeth; Prévot, Sophie; Tardieu, Marc; Goossens, Michel; Tachdjian, Gérard

    2011-01-01

    Pure interstitial deletions of the long arm of chromosome 13 are correlated with variable phenotypes according to the size and the location of the deleted region. Deletions involving the 13q13q21 region are rare. In order to establish interstitial 13q genotype-phenotype correlation, we used high resolution 244K oligonucleotide array in addition to conventional karyotype and molecular (fluorescent in situ hybridization, microsatellite markers analysis) techniques in two independent probands carrying a deletion 13q13 to 13q21. First patient was a 3-year-old girl with mental retardation and dysmorphy carrying a 13q13.3q21.31 de novo deletion diagnosed post-natally. The second one was a fetus with de novo del(13)(q14q21.2) associated with first trimester increased nuchal translucency. We showed that specific dysmorphic features (macrocephaly, high forehead, hypertelorism, large nose, large and malformed ears and retrognathia) were correlated to the common 13q14q21 chromosomal segment. Physical examination revealed overgrowth with global measurement up to the 95th percentile in both probands. This is the second description of overgrowth in patients carrying a 13q deletion. Haploinsufficiency of common candidates genes such as CKAP2, SUGT1, LECT1, DCLK1 and SMAD9, involved in cell division and bone development, is a possible mechanism that could explain overgrowth in both patients. This study underlines also that cytogenetic analysis could be performed in patients with overgrowth.

  2. 3q29 Microdeletion Syndrome: Clinical and Molecular Characterization of a New Syndrome

    PubMed Central

    Willatt, Lionel ; Cox, James ; Barber, John ; Cabanas, Elisabet Dachs ; Collins, Amanda ; Donnai, Dian ; FitzPatrick, David R. ; Maher, Eddy ; Martin, Howard ; Parnau, Josep ; Pindar, Lesley ; Ramsay, Jacqueline ; Shaw-Smith, Charles ; Sistermans, Erik A. ; Tettenborn, Michael ; Trump, Dorothy ; de Vries, Bert B. A. ; Walker, Kate ; Raymond, F. Lucy 

    2005-01-01

    We report the identification of six patients with 3q29 microdeletion syndrome. The clinical phenotype is variable despite an almost identical deletion size. The phenotype includes mild-to-moderate mental retardation, with only slightly dysmorphic facial features that are similar in most patients: a long and narrow face, short philtrum, and high nasal bridge. Autism, gait ataxia, chest-wall deformity, and long and tapering fingers were noted in at least two of six patients. Additional features—including microcephaly, cleft lip and palate, horseshoe kidney and hypospadias, ligamentous laxity, recurrent middle ear infections, and abnormal pigmentation—were observed, but each feature was only found once, in a single patient. The microdeletion is ∼1.5 Mb in length, with molecular boundaries mapping within the same or adjacent bacterial artificial chromosome (BAC) clones at either end of the deletion in all patients. The deletion encompasses 22 genes, including PAK2 and DLG1, which are autosomal homologues of two known X-linked mental retardation genes, PAK3 and DLG3. The presence of two nearly identical low-copy repeat sequences in BAC clones on each side of the deletion breakpoint suggests that nonallelic homologous recombination is the likely mechanism of disease causation in this syndrome. PMID:15918153

  3. 3q29 microdeletion syndrome: clinical and molecular characterization of a new syndrome.

    PubMed

    Willatt, Lionel; Cox, James; Barber, John; Cabanas, Elisabet Dachs; Collins, Amanda; Donnai, Dian; FitzPatrick, David R; Maher, Eddy; Martin, Howard; Parnau, Josep; Pindar, Lesley; Ramsay, Jacqueline; Shaw-Smith, Charles; Sistermans, Erik A; Tettenborn, Michael; Trump, Dorothy; de Vries, Bert B A; Walker, Kate; Raymond, F Lucy

    2005-07-01

    We report the identification of six patients with 3q29 microdeletion syndrome. The clinical phenotype is variable despite an almost identical deletion size. The phenotype includes mild-to-moderate mental retardation, with only slightly dysmorphic facial features that are similar in most patients: a long and narrow face, short philtrum, and high nasal bridge. Autism, gait ataxia, chest-wall deformity, and long and tapering fingers were noted in at least two of six patients. Additional features--including microcephaly, cleft lip and palate, horseshoe kidney and hypospadias, ligamentous laxity, recurrent middle ear infections, and abnormal pigmentation--were observed, but each feature was only found once, in a single patient. The microdeletion is approximately 1.5 Mb in length, with molecular boundaries mapping within the same or adjacent bacterial artificial chromosome (BAC) clones at either end of the deletion in all patients. The deletion encompasses 22 genes, including PAK2 and DLG1, which are autosomal homologues of two known X-linked mental retardation genes, PAK3 and DLG3. The presence of two nearly identical low-copy repeat sequences in BAC clones on each side of the deletion breakpoint suggests that nonallelic homologous recombination is the likely mechanism of disease causation in this syndrome.

  4. [Acute myeloid leukemia with monosomy 7 and inv(3)(q21q26.2) complicated with central diabetes insipidus].

    PubMed

    Nanno, Satoru; Hagihara, Kiyoyuki; Sakabe, Manami; Okamura, Hiroshi; Inaba, Akiko; Nagata, Yuki; Nishimoto, Mitsutaka; Koh, Hideo; Nakao, Yoshitaka; Nakane, Takahiko; Nakamae, Hirohisa; Shimono, Taro; Hino, Masayuki

    2013-04-01

    A 20-year-old female presented with thirst, polyposia, and polyuria and was referred to our hospital because of leukocytosis and anemia. Bone marrow aspiration revealed 66.8% myeloperoxidase-positive blasts and trilineage myelodysplasia. The karyotype was 45, XX, inv(3)(q21q26.2), -7[19]. Therefore, a diagnosis of AML with inv(3)(q21q26.2) complicated by -7 was made. Moreover, hyposthenuria and a low anti-diuretic hormone (ADH) level were observed. Although cerebrospinal fluid analysis was normal, magnetic resonance imaging (MRI) revealed the absence of hyperintensity in the neurohypophysis in T1-weighted images. Therefore, she was also diagnosed with diabetes insipidus. After she was administered a desmopressin nasal spray, the volume of urine produced decreased. Following treatment with second induction therapy containing high-dose cytarabine for AML, she achieved complete remission in the bone marrow. Moreover, when the abnormality on MRI and the volume of urine were normalized, she discontinued desmopressin. Although diabetes insipidus is a rare complication of AML, the majority of AML patients who have diabetes insipidus have the abnormal karyotypes with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and monosomy 7. Further study is required to clarify the pathogenesis and develop a strategy for the treatment of this category of AML.

  5. Minocycline-induced hyperpigmentation: comparison of 3 Q-switched lasers to reverse its effects.

    PubMed

    Nisar, Mahrukh S; Iyer, Karthik; Brodell, Robert T; Lloyd, Jenifer R; Shin, Thuzar M; Ahmad, Asad

    2013-01-01

    Minocycline is a tetracycline derivative antibiotic commonly prescribed for acne, rosacea, and other inflammatory skin disorders. Minocycline turns black when oxidized, leading to discoloration of the skin, nails, bulbar conjunctiva, oral mucosa, teeth, bones, and thyroid gland. Hyperpigmentation has been reported after long-term minocycline therapy with at least 100 mg/day. Three types of minocycline-induced cutaneous hyperpigmentation can result. Type I is the most common, and is associated with blue-black discoloration in areas of previous inflammation and scarring. Type II most commonly affects the legs and is characterized by blue-gray pigmentation of previously normal skin. Type III is the least common and is characterized by diffuse muddy-brown discoloration predominantly on sun exposed skin. Minocycline-induced hyperpigmentation may be cosmetically disfiguring and prompt identification is essential. Without treatment, symptoms may take several months, to years to resolve, after discontinuation of the drug. However, the pigmentation may never completely disappear. In fact, there have been few reports of complete resolution associated with any therapeutic intervention. We report a case of a patient on long-term minocycline therapy utilized as an anti-inflammatory agent to control symptoms of rheumatoid arthritis, which led to minocycline-induced hyperpigmentation of the face. To remove the blue-gray cutaneous deposits, 3 Q-switched lasers (Neodymium: yttrium aluminum garnet (Nd:YAG) 1064 nm, Alexandrite 755 nm, and Ruby 694 nm) were used in test areas. The Alexandrite 755 nm laser proved to provide effective clearing of the minocycline hyperpigmentation requiring just 2 treatments, with minimal treatment discomfort and down time. PMID:23754872

  6. Clinical and prognostic significance of 3q26.2 and other chromosome 3 abnormalities in CML in the era of tyrosine kinase inhibitors.

    PubMed

    Wang, Wei; Cortes, Jorge E; Lin, Pei; Beaty, Michael W; Ai, Di; Amin, Hesham M; McDonnell, Timothy J; Ok, Chi Young; Kantarjian, Hagop M; Medeiros, L Jeffrey; Hu, Shimin

    2015-10-01

    Chromosome 3q26.2 abnormalities in acute myeloid leukemia, including inv(3)/t(3;3) and t(3;21), have been studied and are associated with a poor prognosis. Their prevalence, response to tyrosine kinase inhibitor (TKI) treatment, and prognostic significance in chronic myelogenous leukemia (CML) are largely unknown. In this study, we explored these aspects using a cohort of 2013 patients with CML diagnosed in the era of TKI therapy. Chromosome 3 abnormalities were observed in 116 (5.8%) of 2013 cases. These cases were divided into 5 distinct groups: A, inv(3)(q21q26.2)/t(3;3)(q21;q26.2), 26%; B, t(3;21)(q26.2;q22), 17%; C, other 3q26.2 rearrangements, 7%; D, rearrangements involving chromosome 3 other than 3q26.2 locus, 32%; and E, gain or loss of partial or whole chromosome 3, 18%. In all, 3q26.2 rearrangements were the most common chromosome 3 abnormalities (50%, groups A-C). 3q26.2 rearrangements emerged at different leukemic phases. For cases with 3q26.2 rearrangements that initially emerged in chronic or accelerated phase, they had a high rate of transformation to blast phase. Patients with 3q26.2 abnormalities showed a marginal response to TKI treatment, and no patients achieved a long-term sustainable response at a cytogenetic or molecular level. Compared with other chromosomal abnormalities in CML, patients with 3q26.2 rearrangements had poorer overall survival. The presence or absence of other concurrent chromosomal abnormalities did not affect survival in these patients, reflecting the predominant role of 3q26.2 rearrangements in determining prognosis. Interestingly, although heterogeneous, chromosome 3 abnormalities involving non-3q26.2 loci (groups D, E) also conferred a worse prognosis compared with changes involving other chromosomes in this cohort.

  7. Spectral Line Shapes in the 2ν_3 Q Branch of 12CH_4

    NASA Astrophysics Data System (ADS)

    Devi, V. Malathy; Benner, D. Chris; Sung, Keeyoon; Brown, Linda R.; Crawford, Timothy J.; Yu, Shanshan; Smith, Mary Ann H.; Ismail, Syed; Mantz, Arlan; Boudon, Vincent

    2016-06-01

    We will present the first experimental measurements of spectral line shapes (self- and air-broadened half width, pressure shift, and line mixing (via off-diagonal relaxation matrix element) coefficients and their temperature dependences, where appropriate, for transitions in the 2ν_3 Q branch manifolds of 12CH_4 in the 1.6 μ m region. Employing a multispectrum nonlinear least squares technique, we simultaneously fitted 23 high-resolution spectra of 12CH_4 and mixtures of 12CH_4 in air, recorded at different pressure-temperature combinations between 130 and 296 K. These data were recorded using the Bruker IFS 125 HR Fourier transform spectrometer at the Jet Propulsion Laboratory together with two coolable sample cells. By applying a set of constraints to the parameters of severely blended transitions, a self-consistent set of broadening, shift and line mixing parameters for CH_4-CH_4 and CH_4-air collisions were retrieved. A quadratic speed dependence parameter common for all transitions in each Q(J) manifold was determined. In addition to line shape parameters, line positions and line intensities were also measured for over 100 transitions in the whole Q branch region (5996.5 - 6007.7 cm-1). Comparisons of present results with values in HITRAN2012 will be provided. D.C. Benner, C.P. Rinsland, V. Malathy Devi, M.A. H. Smith, and D. Atkins. JQSRT 53 (1995) 705-721 K. Sung, A.W. Mantz, M.A.H. Smith, L.R. Brown, T.J. Crawford, V.M. Devi, D.C. Benner. J.Mol. Spectrosc. 162 (2010)124-134 A.W. Mantz, K. Sung, T.J. Crawford, L.R. Brown, M.A.H. Smith, V.M. Devi, D.C. Benner, J. Mol. Spectrosc. 304 (2014) 12-24. Research described in this paper are performed at the College of William and Mary, Jet Propulsion Laboratory, California Institute of Technology, Connecticut College, and NASA Langley Research Center under contracts and cooperative agreements with the National Aeronautics and Space Administration.

  8. Quarterly coal report

    SciTech Connect

    Young, P.

    1996-05-01

    The Quarterly Coal Report (QCR) provides comprehensive information about U.S. coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended. This report presents detailed quarterly data for October through December 1995 and aggregated quarterly historical data for 1987 through the third quarter of 1995. Appendix A displays, from 1987 on, detailed quarterly historical coal imports data, as specified in Section 202 of the Energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons.

  9. 6. Interior of quarters (executive officer's quarters), living room, looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Interior of quarters (executive officer's quarters), living room, looking west - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  10. 3. Southwest side of quarters (executive officer's quarters), looking northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Southwest side of quarters (executive officer's quarters), looking northeast - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  11. 1. North side of quarters (executive officer's quarters), looking southeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. North side of quarters (executive officer's quarters), looking southeast - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  12. 4. South side of quarters (executive officer's quarters), looking north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. South side of quarters (executive officer's quarters), looking north - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  13. 2. West side of quarters (executive officer's quarters), looking east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West side of quarters (executive officer's quarters), looking east - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  14. 5. East side of quarters (executive officer's quarters), looking west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. East side of quarters (executive officer's quarters), looking west - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

  15. Contextual view of quarters no. 2 quarters no. 1, and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of quarters no. 2 quarters no. 1, and water tower, looking southwest. - Sacramento National Wildlife Refuge, Headquarters Complex, Quarters No. 2, 752 County Road 99W, Willows, Glenn County, CA

  16. Metallurgical Laboratory Hazardous Waste Management Facility groundwater monitoring report. Second quarter 1995

    SciTech Connect

    Chase, J.A.

    1995-09-01

    During second quarter 1995, samples from seven new AMB groundwater monitoring wells at the Metallurgical Laboratory Hazardous Waste Management Facility (Met Lab HWMF) were analyzed for a comprehensive list of constituents. Two parameters exceeded standards during the quarter. Lead and nickel appear to exceed final Primary Drinking Water Standards (PDWS) in AMB-18A. These data were suspect and a rerun of the samples showed levels below flagging criteria. This data will be monitored in 3Q95. Aluminum, iron, manganese, boron, silver and total organic halogens exceeded Flag 2 criteria in at least one well each during second quarter 1995. This data, as well, will be confirmed by 3Q95 testing. Groundwater flow directions in the M-Area Aquifer Zone were similar to previous quarters; the flow rate estimate, however, differs because of an error noted in the scales of measurements used for previous estimates. The estimate was 470 ft/year during second quarter 1995. Reliable estimates of flow directions and rates in the Upper Lost Lake Aquifer Zone could not be determined in previous quarters because data were insufficient. The first estimate from second quarter 1995 shows a 530 ft/year rate. Reliable estimates of flow directions and rates in the Lower Lost Lake Aquifer Zone and in the Middle Sand Aquifer Zone of the CBCU could not be calculated because of the low horizontal gradient and the near-linear distribution of the monitoring wells. During second quarter 1994, SRS received South Carolina Department of Health and Environmental Control approval for constructing five point-of-compliance wells and two plume definition wells near the Met Lab HWMF. This project began in July 1994 and was completed in March of this year. Analytical data from these wells are presented in this report for the first time.

  17. Financial Aid.

    ERIC Educational Resources Information Center

    Graves, Mary A.

    This workbook assists college and vocational school bound American Indian students in determining their financial needs and in locating sources of financial aid. A checklist helps students assess the state of their knowledge of financial programs; a glossary defines terms pertinent to the realm of financial aid (i.e., graduate study programs,…

  18. Economic Observation in 3Q E-business Fight - According to Analysis of Resource Allocation and Contract

    NASA Astrophysics Data System (ADS)

    Kuang, Ruihu; Chen, Zeming; Kuang, Juchi

    Based on relation of resource allocation and marginal benefit of e-commence provider, both of origin and essence of the 3Q e-business fight were analyzed; and then contents of the contract between e-business company and users were elaborated. Moreover, liability for Qihoo's breach of the contract in 3Q e-business fight was discussed. Analysis of the contract indicated that blame of infringing on privacy of users from public, media or even a law professor for Tengxun Company is not exactly justicial. Some controversial rules which are not fit for usual practices in the QQ contract such as narrow definition of privacy were found out, whose reason lies in no relevant e-business standards or rules in our country. In the end, this passage points out that actions of government who intervened in market operations of Tengxun Company and QQ Company are inappropriate and unnecessary. Thus, responsibility for facing up to incomplete market rules of e-commence lies with government and government should strengthen market supervision by legislation so as to guide healthy development of e-business market, which is a key lesson we learn from the 3Q e-business fight.

  19. Identification of a genetic locus for ichthyosis vulgaris on chromosome 10q22.3-q24.2.

    PubMed

    Liu, Ping; Yang, Qingyu; Wang, Xu; Feng, Aiping; Yang, Tao; Yang, Rong; Wang, Pengyun; Yuang, Mingxiong; Liu, Mugen; Liu, Jing Yu; Wang, Qing K

    2008-06-01

    Ichthyosis vulgaris (IV) is one of the most commonly inherited disorders and has an estimated prevalence rate of 2.29% in China. To date, only one gene responsible for IV, the filaggrin gene (FLG), was identified, but genetic heterogeneity exists. In this study, two Chinese families with autosomal-dominant IV were genetically characterized. The FLG gene was first excluded as the disease-causing gene in the two families. The larger family was then characterized by genome-wide linkage analysis to identify a new genetic locus for IV. Significant linkage was identified with markers on chromosome 10q22.3-q24.2 with a maximum LOD score of 3.19. No other markers showed a LOD score of >1.5. Fine mapping defined the new genetic locus within a 20.7 cM region between markers D10S569 and D10S1709. The second family also showed positive linkage to the same 10q22.3-q24.2 region. The combined maximum LOD score in the two families was 3.95. Identification of linkage in two independent families provides strong genetic evidence that a previously unreported gene for IV is located on chromosome 10q22.3-q24.2. Future studies of the candidate genes at the 10q IV locus will identify a specific gene, which will provide insights into the pathogenesis of IV.

  20. A novel case of unilateral blepharophimosis syndrome and mental retardation associated with de novo trisomy for chromosome 3q.

    PubMed Central

    Cai, T; Tagle, D A; Xia, X; Yu, P; He, X X; Li, L Y; Xia, J H

    1997-01-01

    We have evaluated a 3 2/12 year old girl who presented with unilateral blepharophimosis, ptosis of the eyelid, and mental retardation. Additional dysmorphic features include microcephaly, high, narrow forehead, short stubby fingers, and adduction of the right first toe. Cytogenetic analysis showed an unbalanced karyotype consisting of 46,XX,add(7)(q+) that was de novo in origin. Fluorescence in situ hybridisation (FISH) using microdissected library probe pools from chromosomes 1,2,3,7, and 3q26-qter showed that the additional material on 7q was derived from the distal end of the long arm of chromosome 3. Our results indicate that the patient had an unbalanced translocation, 46,XX,der(7)t(3;7)(q26-qter;q+) which resulted in trisomy for distal 3q. All currently reported cases of BPES (blepharophimosis-ptosis-epicanthus inversus syndrome) with associated cytogenetic abnormalities show interstitial deletions or balanced translocations involving 3q22-q23 or 3p25.3. Our patient shares similar features to BPES, except for the unilateral ptosis and absence of epicanthus inversus. It is possible that our patient has a contiguous gene defect including at least one locus for a type of blepharophimosis, further suggesting that multiple loci exist for eyelid development. Images PMID:9321768

  1. 3Q/4Q99 F-Area Hazardous Waste Management Facility Corrective Action Report - Third and Fourth Quarter 1999, Volumes I and II

    SciTech Connect

    Chase, J.

    2000-05-12

    Savannah River Site (SRS) monitors groundwater quality at the F-Area Hazardous Waste management Facility (HWMF) and provides results of this monitoring to the South Carolina Department of Health and Environmental Control (SCDHEC) semiannually as required by the Resource Conservation and Recovery Act (RCRA) permit. SRS also performs monthly sampling of the Wastewater Treatment Unit (WTU) effluent in accordance with Section C of the Underground Injection Control (UIC) application.

  2. English Leadership Quarterly. 1991.

    ERIC Educational Resources Information Center

    Strickland, James, Ed.

    1991-01-01

    These four issues of the English Leadership Quarterly represent the quarterly for 1991. Articles in number 1 deal with whole language and include: "CEL: Shorter and Better" (Myles D. Eley); "Toward a New Philosophy of Language Learning" (Kathleen Strickland); "Whole Language: Implications for Secondary Classrooms" (Barbara King-Shaver); "Whole…

  3. CSSEDC Quarterly. 1990.

    ERIC Educational Resources Information Center

    Strickland, James, Ed.

    1990-01-01

    These four issues of the CSSEDC Quarterly (Conference for Secondary School English Department Chairpersons) represent the quarterly for 1990. Articles in number 1 deal with student teachers and include: "Student Teaching: Smoothing Out the Rough Spots" (Susan B. Argyle and Fred C. Feitler); "A Partnership for Urban Student Teaching" (Jerome T.…

  4. CSSEDC Quarterly. 1989.

    ERIC Educational Resources Information Center

    Strickland, James, Ed.

    1989-01-01

    These four issues of the CSSEDC Quarterly (Conference for Secondary School English Department Chairpersons) represent the quarterly for 1989. Articles in number 1 deal with professional development, and include: "Sharing Expertise within a Department" (Martha R. Dolly); "Empowerment Develops a Computer Writing Center" (Norman L. Frey); "Videotapes…

  5. The diagnostic utility of combination of HMGA2 and IMP3 qRT-PCR testing in thyroid neoplasms.

    PubMed

    Jin, Long; Lloyd, Ricardo V; Henry, Michael R; Erickson, Lori A; Sebo, Thomas J; Rumilla, Kandelaria M; Zhang, Jun

    2015-01-01

    The diagnosis of malignant thyroid tumors in some cytologic and histologic specimens remains challenging. High-mobility group A2 (HMGA2) expression and insulin-like growth factor II mRNA-binding protein-3 (IMP3) expression were evaluated by relative quantitative reverse transcription-polymerase chain reaction (qRT-PCR). The aim of this study was to evaluate whether the combination of HMGA2 and IMP3 qRT-PCR was diagnostically useful in differentiating benign from malignant thyroid neoplasms. Fine-needle aspiration (FNA) specimens from 120 patients including 56 benign lesions and 64 carcinomas were used. The available 80 corresponding formalin-fixed paraffin-embedded (FFPE) thyroid tissues from 66 patients were also included in this study. HMGA2 and IMP3 expression levels were detected by qRT-PCR and reported as relative fold change after normalizing with a calibrator. The diagnostic utilities of HMGA2 and IMP3 qRT-PCR tests were evaluated individually and in combination. In FNA specimens, HMGA2 and IMP3 expression was consistently higher in thyroid malignancies compared with benign lesions in all subgroups except in Hürthle cell tumors. After exclusion of Hürthle cell tumors, the sensitivity was 90.2% for HMGA2, 88.2% for IMP3, and 98% for HMGA2+IMP3; the specificity was 97.1% for HMGA2, 79.4% for IMP3, and 79.4% for HMGA+IMP3. qRT-PCR data showed similar results in FFPE tissues: the sensitivity was 84.2% for HMGA2, 85.7% for IMP3, and 94.7% for HMGA2+IMP3; the specificity was 96.9% for HMGA2, 91.2% for IMP3, and 90.6% for HMGA2+IMP3. qRT-PCR data were concordant between FNA and FFPE samples for HMGA2 (97.4%) and IMP3 (96.9%). The results indicate that HMGA2 qRT-PCR with high specificity may be a useful ancillary technique to assist in the classification of difficult thyroid specimens, excluding Hürthle cell tumors. The HMGA2 and IMP3 qRT-PCR combination model with increased sensitivity and negative predictive value (96.4%) may be useful in screening thyroid

  6. [Molecular characterisation and phenotypic description of two patients with reciprocal chromosomal aberrations in the region of the 3q29 microdeletion/microduplication syndromes].

    PubMed

    Quintela, I; Barros-Angueira, F; Perez-Gay, L; Dacruz, D; Castro-Gago, M; Carracedo, A; Eiris-Punal, J

    2015-09-16

    Introduccion. Los sindromes de microdelecion y microduplicacion 3q29 se caracterizan por una marcada heterogeneidad fenotipica, y el retraso del desarrollo y la discapacidad intelectual de grado leve-moderado son las manifestaciones clinicas mas frecuentes. Casos clinicos. Dos pacientes con aberraciones cromosomicas reciprocas en la region 3q29. La paciente con la microdelecion 3q29 presenta dificultades de aprendizaje, microcefalia limite, dismorfismo facial leve, deficit atencional e impulsividad, y rasgos ansiosos y obsesivos. El paciente con la microduplicacion 3q29 reciproca presenta dificultades de aprendizaje, dismorfismo facial leve y un perfil conductual disruptivo no asociado previamente con esta duplicacion. Conclusion. Se comparan los fenotipos de estos pacientes y se revisa la bibliografia de pacientes pediatricos con microdeleciones y microduplicaciones 3q29.

  7. 4. Northeast corner of quarters (executive officer's quarters), looking onto ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Northeast corner of quarters (executive officer's quarters), looking onto Quarter R (commanding officer's quarters), looking southeast - Naval Air Station Chase Field, Texas State Highway 202, 4.8 miles east of intersection of Texas State Highway 202 & U.S. State Highway 181, Beeville, Bee County, TX

  8. Ocean thermal energy. Quarterly report, January-March 1982

    SciTech Connect

    Not Available

    1982-03-30

    This quarterly report summarizes work of the following tasks as of March 31, 1982: OTEC pilot plant conceptual design review; OTEC methanol; review of electrolyzer development programs and requirements; financial and legal considerations in OTEC implementation; potential Navy sites for GEOTEC systems; hybrid geothermal-OTEC power plants: single-cycle performance estimates; and supervision of testing of pneumatic wave energy conversion system.

  9. Ocean energy systems. Quarterly report, July-September 1982

    SciTech Connect

    Not Available

    1982-09-30

    This quarterly report summarizes work on the following tasks as of September 30, 1982: (1) OTEC pilot plant conceptual design review; (2) OTEC methanol; (3) financial and legal considerations in OTEC implementation; (4) GEOTEC resource exploration at Adak, Alaska, and Lualualei, Hawaii; (5) preliminary GEOTEC plant cost estimates; and (6) supervision of testing of pneumatic wave energy conversion system.

  10. Parachute Creek Shale Oil Program Environmental Monitoring Program. Quarterly report, fourth quarter, October 1-December 31, 1991

    SciTech Connect

    Not Available

    1992-02-28

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commercial-scale synthetic fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The Program agreed to comply with existing environmental monitoring regulations and to develop an Environmental Monitoring Plan (EMP) incorporating supplemental monitoring in the areas of water, air, solid waste, and worker health and safety during the period 1985-1992. These activities are described in a series of quarterly and annual reports. The document contains environmental compliance data collected in the fourth quarter of 1991, contents of reports on compliance data submitted to regulatory agencies, and supplemental analytical results from retorted shale pile runoff water collected following a storm event during the third quarter of 1991.

  11. 39 CFR 3050.40 - Additional financial reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Additional financial reporting. 3050.40 Section 3050.40 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PERIODIC REPORTING § 3050.40 Additional financial reporting. (a) In general. The Postal Service shall file with the Commission: (1) Within 40 days after the end of each fiscal quarter,...

  12. 7 CFR 550.53 - Financial reporting.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Financial reporting. 550.53 Section 550.53 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF... quarterly and semi-annual reports, and 90 calendar days for annual and final reports. Extensions...

  13. 7 CFR 550.53 - Financial reporting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Financial reporting. 550.53 Section 550.53 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF... quarterly and semi-annual reports, and 90 calendar days for annual and final reports. Extensions...

  14. Genetic linkage of autosomal dominant primary open angle glaucoma to chromosome 3q in a Greek pedigree.

    PubMed

    Kitsos, G; Eiberg, H; Economou-Petersen, E; Wirtz, M K; Kramer, P L; Aspiotis, M; Tommerup, N; Petersen, M B; Psilas, K

    2001-06-01

    A locus for juvenile onset open angle glaucoma (OAG) has been assigned to chromosome 1q in families with autosomal dominant inheritance (GLC1A), due to mutations in the TIGR/MYOC gene. For adult onset OAG, called primary open angle glaucoma or POAG, five loci have so far been mapped to different chromosomes (GLC1B-GLC1F). Except for the GLC1B locus, the other POAG loci have so far been reported only in single large pedigrees. We studied a large family identified in Epirus, Greece, segregating POAG in an autosomal dominant fashion. Clinical findings included increased cup to disc ratio (mean 0.7), characteristic glaucomatous changes in the visual field, and intraocular pressure before treatment more than 21 mmHg (mean 31 mmHg), with age at diagnosis 33 years and older. Linkage analysis was performed between the disease phenotype and microsatellite DNA polymorphisms. Linkage was established with a group of DNA markers located on chromosome 3q, where the GLC1C locus has previously been described in one large Oregon pedigree. A maximal multipoint lod score of 3.88 was obtained at marker D3S1763 (penetrance 80%). This represents the second POAG family linked to the GLC1C locus on chromosome 3q, and haplotype analysis in the two families suggests an independent origin of the genetic defect.

  15. 31 CFR 30.3 - Q-3: How are the SEOs and most highly compensated employees identified for purposes of compliance...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Finance: Treasury Office of the Secretary of the Treasury TARP STANDARDS FOR COMPENSATION AND CORPORATE GOVERNANCE § 30.3 Q-3: How are the SEOs and most highly compensated employees identified for purposes...

  16. EMSL Quarterly Highlights Report: 1st Quarter, FY08

    SciTech Connect

    Showalter, Mary Ann

    2008-01-28

    The EMSL Quarterly Highlights Report covers the science, staff and user recognition, and publication activities that occurred during the 1st quarter (October 2007 - December 2007) of Fiscal Year 2008.

  17. EMSL Quarterly Highlights Report: FY 2008, 3rd Quarter

    SciTech Connect

    Showalter, Mary Ann

    2008-09-16

    The EMSL Quarterly Highlights Report covers the science, staff and user recognition, and publication activities that occurred during the 1st quarter (October 2007 - December 2007) of Fiscal Year 2008.

  18. EMSL Quarterly Highlights Report: 1st Quarter, Fiscal Year 2009

    SciTech Connect

    Showalter, Mary Ann; Kathmann, Loel E.; Manke, Kristin L.

    2009-02-02

    The EMSL Quarterly Highlights Report covers the science, staff and user recognition, and publication activities that occurred during the 1st quarter (October 2008 - December 2008) of Fiscal Year 2009.

  19. Financial Literacy, Financial Education, and Economic Outcomes

    ERIC Educational Resources Information Center

    Hastings, Justine S.; Madrian, Brigitte C.; Skimmyhorn, William L.

    2013-01-01

    In this article, we review the literature on financial literacy, financial education, and consumer financial outcomes. We consider how financial literacy is measured in the current literature and examine how well the existing literature addresses whether financial education improves financial literacy or personal financial outcomes. We discuss the…

  20. Short-term energy outlook. Quarterly projections, second quarter 1996

    SciTech Connect

    1996-04-01

    The Energy Information Administration prepares quarterly, short-term energy supply, demand, and price projections. The forecasts in this issue cover the second quarter of 1996 through the fourth quarter of 1997. Changes to macroeconomic measures by the Bureau of Economic Analysis have been incorporated into the STIFS model used.

  1. The existence of Usher syndrome type III proven by assignment of its locus to chromosome 3q by linkage

    SciTech Connect

    Sankila, E.M.; Aittomaeki, K.; Kaeaeriaeinen, H.

    1994-09-01

    Usher syndromes (USH) are genetically and clinically heterogeneous autosomal recessive disorders with combined visual and hearing loss. Usher syndrome type III (USH3) is characterized by progressive bilateral sensorineural deafness and progressive pigmentary retinopathy leading to blindness. USH3 has been conservatively estimated to comprise 2% of the three clinical USH types, and its existence has even been questioned. However, based on clinical criteria, in Finland 42% of USH patients have USH3 suggesting gene enrichment by a founder effect. Genes whose defects cause USH have so far been mapped to four different locations in three chromosomes. We have excluded the previously mapped USH regions as the site of USH3 disease locus. Systematic search for USH3 by genetic linkage analyses of 11 multiple affected families using highly polymorphic microsatellite markers revealed significant linkage with five markers mapping to chromosome 3q. Two-point lod scores at zero recombination distance were 5.24 for D3S1308, and 7.71 for D3S1299, respectively. Multipoint linkage analysis gave a maximum lod score of 8.68 at D3S1299 assigning USH3 to the 4 cM interval between markers D3S1555 and D3S1279 in 3q21-25. Of 20 parental disease chromosomes, 15 had identical alleles at three marker loci covering 3 cM genetic distance and the putative USH3 mutation. These findings prove the existence of USH3 as a distinct entity, pinpoint a fifth USH locus, and suggest enrichment of a major mutation in the isolated Finnish population.

  2. Rs710521[A] on chromosome 3q28 close to TP63 is associated with increased urinary bladder cancer risk.

    PubMed

    Lehmann, Marie-Louise; Selinski, Silvia; Blaszkewicz, Meinolf; Orlich, Michael; Ovsiannikov, Daniel; Moormann, Oliver; Guballa, Christoph; Kress, Alexander; Truss, Michael C; Gerullis, Holger; Otto, Thomas; Barski, Dimitri; Niegisch, Günter; Albers, Peter; Frees, Sebastian; Brenner, Walburgis; Thüroff, Joachim W; Angeli-Greaves, Miriam; Seidel, Thilo; Roth, Gerhard; Dietrich, Holger; Ebbinghaus, Rainer; Prager, Hans M; Bolt, Hermann M; Falkenstein, Michael; Zimmermann, Anna; Klein, Torsten; Reckwitz, Thomas; Roemer, Hermann C; Löhlein, Dietrich; Weistenhöfer, Wobbeke; Schöps, Wolfgang; Beg, Anwer E; Aslam, Muhammad; Bánfi, Gergely; Romics, Imre; Ickstadt, Katja; Schwender, Holger; Winterpacht, Andreas; Hengstler, Jan G; Golka, Klaus

    2010-12-01

    Single nucleotide polymorphism (SNP) rs710521[A], located near TP63 on chromosome 3q28, was identified to be significantly associated with increased bladder cancer risk. To investigate the association of rs710521[A] and bladder cancer by new data and by meta-analysis including all published data, rs710521 was studied in 1,425 bladder cancer cases and 1,740 controls that had not been included in previous studies. Blood samples were collected from 1995 to 2010 in Germany (n = 948/1,258), Hungary (n = 262/65), Venezuela (n = 112/190) and Pakistan (n = 103/227) supplemented by a meta-analysis of 5,695 cases and 40,187 controls. Detection of a A/G substitution (rs710521) on chromosome 3q28, position 191128627 was done via fast real-time polymerase chain reaction (rt-PCR). Rs710521[A] is associated with increased risk in the unadjusted analysis (OR = 1.21; 95% Cl = 1.04-1.40; P = 0.011) and in the recessive model adjusted for age, gender, smoking habits and ethnicity (OR = 1.23; 95% Cl = 1.05-1.44; P = 0.010). No difference between individuals occupationally exposed versus not occupationally exposed to urinary bladder carcinogens was observed concerning the relevance of rs710521[A]. Similarly, rs710521[A] did not confer different susceptibility in smokers and non-smokers. Performing a meta-analysis of 5,695 cases and 40,187 controls including all published studies on rs710521, a convincing association with bladder cancer risk was obtained (OR = 1.18; 95% Cl = 1.12-1.25; P < 0.0001). However, the odds ratio is relatively small.

  3. Quarterly environmental data summary for first quarter 1999

    SciTech Connect

    1999-06-01

    In support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement, a copy of the Quarterly Environmental Data Summary (QEDS) for the first quarter of 1999 is enclosed. The data presented in this constitute the QEDS. The data, except for air monitoring data and site KPA generated data (uranium analyses), were received from the contract laboratories, verified by the Weldon Spring Site verification group and merged into the database during the first quarter of 1999. KPA results for on-site total uranium analyses performed during first quarter 1999 are included. Air monitoring data presented are the most recent complete sets of quarterly data.

  4. English Leadership Quarterly, 1993.

    ERIC Educational Resources Information Center

    Strickland, James, Ed.

    1993-01-01

    These four issues of the English Leadership Quarterly represent those published during 1993. Articles in number 1 deal with parent involvement and participation, and include: "Opening the Doors to Open House" (Jolene A. Borgese); "Parent/Teacher Conferences: Avoiding the Collision Course" (Robert Perrin); "Expanding Human Resources: Trained…

  5. English Leadership Quarterly, 1995.

    ERIC Educational Resources Information Center

    Kiernan, Henry, Ed.

    1995-01-01

    These 4 issues of the English Leadership Quarterly comprise volume 17, published during 1995. Articles in number 1 deal with multicultural and multiethnic literature, and are, as follows: "Guidelines for Selecting European Ethnic Literature for Interdisciplinary Courses" (Sandra Stotsky); "Striving for Kinship within Diverse Communities" (Peter…

  6. Trustee Quarterly, 1997.

    ERIC Educational Resources Information Center

    Hutchins, Sally, Ed.

    1997-01-01

    These four issues of "Trustee Quarterly" focus on current topics affecting community college trustees. Issue 1 focuses on the learning revolution and serves as a guide for community college trustees. It offers the following feature articles by Terry O'Banion: "Education Reform: Two Waves,""The Second Wave and the Community College,""The House that…

  7. Gifted Education Quarterly, 1998.

    ERIC Educational Resources Information Center

    Fisher, Maurice, Ed.

    1998-01-01

    These four issues of "Gifted Education Quarterly" include the following articles: (1) "Using Test Results To Support Clinical Judgment" (Linda Kreger Silverman), which discusses some of the difficulties in obtaining accurate indications of a child's level of giftedness and the importance of using professional judgment in determining whether tests…

  8. English Leadership Quarterly, 1992.

    ERIC Educational Resources Information Center

    Strickland, James, Ed.

    1992-01-01

    These four issues of the English Leadership Quarterly represent those published during 1992. Articles in number 1 deal with testing assessing, and measuring student performance, and include: "Real Evaluation: Portfolios as an Effective Alternative to Standardized Testing" (Kate Kiefer); "No More Objective Tests, Ever" (Carol Jago); "Process-Based…

  9. Financial Opportunities

    SciTech Connect

    2012-01-19

    The Water Power Program focuses on technological development, and deployment of innovative technologies capable of generating electricity from water. The program funds research and development activities through competitive solicitations. Financial opportunities are avaliable here.

  10. Financial Assistance

    MedlinePlus

    Health care can be costly. If you have health insurance, it usually pays at least part of your medical costs. If you don't have insurance or need help with costs that aren't covered, financial assistance ...

  11. Strategic Petroleum Reserve quarterly report

    SciTech Connect

    Not Available

    1993-08-15

    This Quarterly Report highlights activities undertaken during the second quarter of calendar year 1993, including: inventory of petroleum products stored in the Reserve, under contract and in transit at the end of the calendar quarter; fill rate for the current quarter and projected fill rate for the next calendar quarter; average price of the petroleum products acquired during the calendar quarter; current and projected storage capacity and plans to accelerate the acquisition or construction of such capacity; analysis of existing or anticipated problems with the acquisition and storage of petroleum products, and future expansion of storage capacity; funds obligated by the Secretary from the SPR Petroleum Account and the Strategic Petroleum Reserve Account during the prior calendar quarter and in total; and major environmental actions completed, in progress, or anticipated.

  12. Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13

    PubMed Central

    Thompson, Susan D.; Marion, Miranda C.; Sudman, Marc; Ryan, Mary; Tsoras, Monica; Howard, Timothy D.; Barnes, Michael G.; Ramos, Paula S.; Thomson, Wendy; Hinks, Anne; Haas, Johannes P.; Prahalad, Sampath; Bohnsack, John F.; Wise, Carol A.; Punaro, Marilynn; Rosé, Carlos D.; Pajewski, Nicholas M.; Spigarelli, Michael; Keddache, Mehdi; Wagner, Michael; Langefeld, Carl D.; Glass, David N.

    2012-01-01

    Objective We have conducted a GWAS in a Caucasian cohort of juvenile idiopathic arthritis (JIA) patients and have previously published findings limited to autoimmune loci shared with other diseases. The goal of this study was to identify novel JIA predisposing loci using genome-wide approaches. Methods The Discovery cohort consisted of Caucasian JIA cases (814) and local controls (658) genotyped on the Affymetrix SNP 6.0 Array along with 2400 out-of-study controls. A replication study consisted of 10 SNPs genotyped in 1744 cases and 7010 controls from the US and Europe. Results Analysis within the Discovery cohort provided evidence of associations at 3q13 within C3orf1 and near CD80 (rs4688011, OR=1.37, P=1.88×10−6), and 10q21 near the gene JMJD1C [rs6479891, odds ratio (OR) =1.59, P=6.1×10−8; rs12411988, OR=1.57, P=1.16×10−7 and rs10995450, OR = 1.31, P=6.74×10−5]. Meta-analysis continued to provide evidence for association for these 4 SNPs (rs4688011, P=3.6×10−7, rs6479891, P=4.33×10−5; rs12411988, P=2.71×10−5; and rs10995450, 5.39×10−5;). Gene expression data from 68 JIA cases and 23 local controls showed cis eQTL associations for C3orf1 SNP rs4688011 (P=0.024 or P=0.034, depending on probe set) and the JMJD1C SNPs rs6479891 and rs12411988 (P=0.01 and P=0.008, respectively). A variance component liability model estimated that common SNP variation accounts for ~1/3 of JIA susceptibility. Conclusions Genetic association results and correlated gene expression findings provide evidence of association at 3q13 and 10q21 for JIA and offer novel genes as plausible candidates in disease pathology. PMID:22354554

  13. A gene prenature ovarian failure associated with eyelid malformation maps to chromosomes 3q22-q23

    SciTech Connect

    1996-05-01

    Premature ovarian failure and XX gonadal dysgenesis leading to female infertility have been reported in association with an autosomal dominantly inherited malformation of the eyelids: blepharophimosis-ptosis-epicanthus inversus syndrome (BPES; MIM 110100). This association distinguishes BPES type I from BPES type II, in which affected females are fertile and the transmission occurs through both sexes. Recently, a gene responsible for BPES type II has been mapped to chromosome 3q22-q23, and the critical region for the gene location has been reduced to the interval between loci D3S1615 and D3S1316. Hitherto, however, no information regarding the localization of the gene for BPES type I, in which female ovarian failure is associated with eyelid malformation, has been available. We have studied two independent families affected with BPES type I, including a total of 12 affected individuals (6 infertile women) and 6 healthy relatives. The diagnostic criteria for the ophthalmological anomaly included (1) reduced horizontal diameter of palpebral fissures, (2) drooping of the upper eyelids, and (3) an abnormal skinfold running from the lower lids. Telecanthus and a flat nasal bridge were present in most cases. In both families the disease was transmitted only by the male, and no affected woman of childbearing age was fertile. 12 refs., 2 figs., 1 tab.

  14. Autosomal recessive spastic paraplegia (SPG45) with mental retardation maps to 10q24.3-q25.1.

    PubMed

    Dursun, Umut; Koroglu, Cigdem; Kocasoy Orhan, Elif; Ugur, Sibel Aylin; Tolun, Aslihan

    2009-10-01

    Hereditary spastic paraplegias (HSPs) are characterized by progressive spasticity in the lower limbs. They are clinically heterogeneous, and pure forms as well as complicated forms with other accompanying clinical findings are known. HSPs are also genetically heterogeneous. We performed clinical and genetic studies in a consanguineous family with five affected members. A genome scan using 405 microsatellite markers for eight members of the family identified candidate gene loci, and subsequent fine mapping in 16 members identified the gene locus responsible for the HSP. The clinical manifestations were very early onset spastic paraplegia (SPG) accompanied by mental retardation and ocular signs. The gene locus was identified as the interval 102.05-106.64 Mbp on chromosome 10. Gene MRPL43 was analyzed in the patients. No mutation but high levels of mRNA were detected. We have mapped a novel autosomal recessive complicated form of HSP (SPG45) to a 4.6-Mbp region at 10q24.3-q25.1 with multipoint logarithm of odds scores >4.5.

  15. Parachute Creek Shale Oil Program Environmental Monitoring Program. Quarterly report, third quarter, July 1-September 30, 1991

    SciTech Connect

    Not Available

    1991-11-30

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commercial-scale synthetic fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The Program agreed to comply with existing environmental monitoring regulations and to develop an Environmental Monitoring Plan (EMP) incorporating supplemental monitoring in the areas of water, air, solid waste, and worker health and safety during the period 1985-1992. These activities are described in a series of quarterly and annual reports. The document contains nine compliance reports and results of comprehensive and supplemental environmental monitoring conducted during the third quarter of 1991.

  16. Quarterly oil report

    SciTech Connect

    Not Available

    1990-07-01

    This report contains information on petroleum fuels market activity in California. Included is information on price trends, refinery activities, production, and petroleum company financial statements. 10 fig., 6 tabs. (CBS)

  17. Short-term energy outlook. Quarterly projections, Third quarter 1995

    SciTech Connect

    1995-08-02

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent projections with those of other forecasting services, and discusses current topics related to the short-term energy markets. The forecast period for this issue of the Outlook extends from the third quarter of 1995 through the fourth quarter of 1996. Values for the second quarter of 1995, however, are preliminary EIA estimates.

  18. FINANCIAL LITERACY, FINANCIAL EDUCATION AND ECONOMIC OUTCOMES

    PubMed Central

    Hastings, Justine S.; Madrian, Brigitte C.; Skimmyhorn, William L.

    2013-01-01

    In this article we review the literature on financial literacy, financial education, and consumer financial outcomes. We consider how financial literacy is measured in the current literature, and examine how well the existing literature addresses whether financial education improves financial literacy or personal financial outcomes. We discuss the extent to which a competitive market provides incentives for firms to educate consumers or offer products that facilitate informed choice. We review the literature on alternative policies to improve financial outcomes, and compare the evidence to evidence on the efficacy and cost of financial education. Finally, we discuss directions for future research. PMID:23991248

  19. Tetrasomy 3q26.32-q29 due to a supernumerary marker chromosome in a child with pigmentary mosaicism of Ito

    PubMed Central

    Cunha, Karina S.; Simioni, Milena; Vieira, Tarsis P.; Gil-da-Silva-Lopes, Vera L.; Puzzi, Maria B.; Steiner, Carlos E.

    2016-01-01

    Abstract Pigmentary mosaicism of Ito (PMI) is a skin abnormality often characterized by hypopigmentation of skin, following, in most cases, the Blaschko lines, usually associated with extracutaneous abnormalities, especially abnormalities of the central nervous system (CNS). It is suggested that this pattern arises from the presence and migration of two cell lineages in the ectoderm layer during the embryonic period and embryonic cell migration, with different gene expression profiles associated with pigmentation. Several types of chromosomal aberrations, with or without mosaicism, have been associated with this disorder. This study comprised clinical description and cytogenetic analysis of a child with PMI. The G-banded karyotype analysis revealed a supernumerary marker chromosome in 76% of the analyzed metaphases from peripheral blood lymphocytes. Array genomic hybridization analysis showed a copy number gain between 3q26.32-3q29, of approximately 20.5 Mb. Karyotype was defined as 47,XX,+mar[38]/46,XX[12].arr 3q26.32-3q29(177,682,859- 198,043,720)x4 dn. Genes mapped in the overlapping region among this patient and three other cases described prior to this study were listed and their possible involvement on PMI pathogenesis is discussed. PMID:27007896

  20. Assignment of the human cytosolic acetoacetyl-coenzyme a thiolase (ACAT2) gene to chromosome 6q25.3-q26

    SciTech Connect

    Masuno, Mitsuo; Imaizumi, Kiyoshi; Kuroki, Yoshikazu

    1996-08-15

    This report describes the localization of the human cytosolic acetoacetyl-coenzyme A thiolase (ACAT2) gene to human chromosome 6q25.3-q26 using fluorescence in situ hybridization. ACAT2 is involved in steroid biosynthesis; deficiency of this coenzyme results in a phenotype which includes severe mental retardation. 11 refs., 1 fig.

  1. Tetrasomy 3q26.32-q29 due to a supernumerary marker chromosome in a child with pigmentary mosaicism of Ito.

    PubMed

    Cunha, Karina S; Simioni, Milena; Vieira, Tarsis P; Gil-da-Silva-Lopes, Vera L; Puzzi, Maria B; Steiner, Carlos E

    2016-03-01

    Pigmentary mosaicism of Ito (PMI) is a skin abnormality often characterized by hypopigmentation of skin, following, in most cases, the Blaschko lines, usually associated with extracutaneous abnormalities, especially abnormalities of the central nervous system (CNS). It is suggested that this pattern arises from the presence and migration of two cell lineages in the ectoderm layer during the embryonic period and embryonic cell migration, with different gene expression profiles associated with pigmentation. Several types of chromosomal aberrations, with or without mosaicism, have been associated with this disorder. This study comprised clinical description and cytogenetic analysis of a child with PMI. The G-banded karyotype analysis revealed a supernumerary marker chromosome in 76% of the analyzed metaphases from peripheral blood lymphocytes. Array genomic hybridization analysis showed a copy number gain between 3q26.32-3q29, of approximately 20.5 Mb. Karyotype was defined as 47,XX,+mar[38]/46,XX[12].arr 3q26.32-3q29(177,682,859- 198,043,720)x4 dn. Genes mapped in the overlapping region among this patient and three other cases described prior to this study were listed and their possible involvement on PMI pathogenesis is discussed. PMID:27007896

  2. A novel microdeletion syndrome involving 5q14.3-q15: clinical and molecular cytogenetic characterization of three patients

    PubMed Central

    Engels, Hartmut; Wohlleber, Eva; Zink, Alexander; Hoyer, Juliane; Ludwig, Kerstin U; Brockschmidt, Felix F; Wieczorek, Dagmar; Moog, Ute; Hellmann-Mersch, Birgit; Weber, Ruthild G; Willatt, Lionel; Kreiß-Nachtsheim, Martina; Firth, Helen V; Rauch, Anita

    2009-01-01

    Molecular karyotyping is being increasingly applied to delineate novel disease causing microaberrations and related syndromes in patients with mental retardation of unknown aetiology. We report on three unrelated patients with overlapping de novo interstitial microdeletions involving 5q14.3-q15. All three patients presented with severe psychomotor retardation, epilepsy or febrile seizures, muscular hypotonia and variable brain and minor anomalies. Molecular karyotyping revealed three overlapping microdeletions measuring 5.7, 3.9 and 3.6 Mb, respectively. The microdeletions were identified using single nucleotide polymorphism (SNP) arrays (Affymetrix 100K and Illumina 550K) and array comparative genomic hybridization (1 Mb Sanger array-CGH). Confirmation and segregation studies were performed using fluorescence in situ hybridization (FISH) and quantitative PCR. All three aberrations were confirmed and proven to have occurred de novo. The boundaries and sizes of the deletions in the three patients were different, but an overlapping region of around 1.6 Mb in 5q14.3 was defined. It included five genes: CETN3, AC093510.2, POLR3G, LYSMD3 and the proximal part of GPR98/MASS1, a known epilepsy gene. Haploinsufficiency of GPR98/MASS1 is probably responsible for the seizure phenotype in our patients. At least one other gene contained in the commonly deleted region, LYSMD3, shows a high level of central nervous expression during embryogenesis and is also, therefore, a good candidate gene for other central nervous system (CNS) symptoms, such as psychomotor retardation, brain anomalies and muscular hypotonia of the 5q14.3 microdeletion syndrome. PMID:19471318

  3. Spectral line parameters including line shapes in the 2ν3 Q branch of 12CH4

    NASA Astrophysics Data System (ADS)

    Devi, V. Malathy; Benner, D. Chris; Sung, Keeyoon; Brown, Linda R.; Crawford, Timothy J.; Yu, Shanshan; Smith, Mary Ann H.; Mantz, Arlan W.; Boudon, Vincent; Ismail, Syed

    2016-07-01

    In this study, we report the first experimental measurements of spectral line shape parameters (self- and air-broadened Lorentz half-widths, pressure-shifts, and line mixing (via off-diagonal relaxation matrix elements) coefficients and their temperature dependences, where appropriate) for transitions in the 2ν3 Q branch manifolds, Q(11)-Q(1) of methane (12CH4), in the 5996.5-6007-cm-1 region. The analysis included 23 high-resolution, high signal-to-noise laboratory absorption spectra recorded with the Bruker IFS-125HR Fourier transform spectrometer (FTS) at JPL. The experimental data were obtained using 12C-enriched 12CH4 and dilute mixtures of 12CH4 in dry air in the 130-296 K range using a room-temperature long path absorption cell and, two custom-built coolable cells. In the analysis, an interactive multispectrum fitting software was employed where all the 23 spectra (11 self-broadened and 12 air-broadened) were fit simultaneously. By carefully applying reasonable constraints to the parameters for severely blended lines, we were able to determine a self-consistent set of broadening, shift and line mixing (relaxation matrix coefficients) parameters for CH4-CH4 and CH4-air collisions. In the majority of cases, a quadratic speed dependence parameter common for all transitions in each Q(J) manifold was determined. However, temperature dependences of the Q branch line mixing parameter could not be determined from the present data. Since no other experimental line shape measurements have been reported for this Q-branch, the present results are compared to available values in the HITRAN2012 database.

  4. Molecular cytogenetic characterisation of a mosaic add(12)(p13.3) with an inv dup(3)(q26.31 → qter) detected in an autistic boy

    PubMed Central

    Carreira, Isabel M; Melo, Joana B; Rodrigues, Carlos; Backx, Liesbeth; Vermeesch, Joris; Weise, Anja; Kosyakova, Nadezda; Oliveira, Guiomar; Matoso, Eunice

    2009-01-01

    Background Inverted duplications (inv dup) of a terminal chromosome region are a particular subset of rearrangements that often results in partial tetrasomy or partial trisomy when accompanied by a deleted chromosome. Associated mosaicism could be the consequence of a post-zygotic event or could result from the correction of a trisomic conception. Tetrasomies of distal segments of the chromosome 3q are rare genetic events and their phenotypic manifestations are diverse. To our knowledge, there are only 12 cases reported with partial 3q tetrasomy. Generally, individuals with this genomic imbalance present mild to severe developmental delay, facial dysmorphisms and skin pigmentary disorders. Results We present the results of the molecular cytogenetic characterization of an unbalanced mosaic karyotype consisting of mos 46,XY,add(12)(p13.3) [56]/46,XY [44] in a previously described 11 years old autistic boy, re-evaluated at adult age. The employment of fluorescence in situ hybridization (FISH) and multicolor banding (MCB) techniques identified the extra material on 12p to be derived from chromosome 3, defining the additional material on 12p as an inv dup(3)(qter → q26.3::q26.3 → qter). Subsequently, array-based comparative genomic hybridization (aCGH) confirmed the breakpoint at 3q26.31, defining the extra material with a length of 24.92 Mb to be between 174.37 and 199.29 Mb. Conclusion This is the thirteenth reported case of inversion-duplication 3q, being the first one described as an inv dup translocated onto a non-homologous chromosome. The mosaic terminal inv dup(3q) observed could be the result of two proposed alternative mechanisms. The most striking feature of this case is the autistic behavior of the proband, a characteristic not shared by any other patient with tetrasomy for 3q26.31 → 3qter. The present work further illustrates the advantages of the use of an integrative cytogenetic strategy, composed both by conventional and molecular techniques, on

  5. Financial Analysis

    NASA Astrophysics Data System (ADS)

    Haimovitch, Larry

    1988-09-01

    This is my second annual State-Of-The-Industry, if you will, from the financial standpoint. Swergold, Chefitz & Sinsabaugh, so you understand my position a little bit better, is both an investment banking and institutional research firm. We specialize both in healthcare research and in high technology research. I am one of three healthcare analysts. I am one of the fortunate ones who get to be in the San Francisco office. My speciality includes, in the medical device and technology areas, such subsectors as medical lasers, ophthalmology, critical care medicine, orthopedic devices, and cardiovascular devices. I have followed the medical laser industry for the last few years, and what I wanted to do today was give you kind of an update on the financial state of the industry.

  6. Strategic petroleum reserve. Quarterly report

    SciTech Connect

    Not Available

    1994-05-15

    The Strategic Petroleum Reserve serves as one of our most important investments in reducing the Nation`s vulnerability to oil supply disruptions. Its existence provides an effective response mechanism should a disruption occur and a formidable deterrent to the use of oil as a political instrument. The Strategic Petroleum Reserve was created pursuant to the Energy Policy and Conservation Act of December 22, 1975, (Public Law 94-163) as amended, to reduce the impact of disruptions in supplies of petroleum products and to carry out obligations of the United States under the Agreement on an International Energy Program. Section 165(a) of the Act requires the submission of Annual Reports and Section 165(b)(1) requires the submission of Quarterly Reports. This Quarterly Report highlights activities undertaken during the first quarter of calendar year 1994, including: (1) inventory of petroleum products stored in the Reserve, under contract and in transit at the end of the calendar quarter; (2) fill rate for the current quarter and projected fill rate for the next calendar quarter; (3) average price of the petroleum products acquired during the calendar quarter; (4) current and projected storage capacity; (5) analysis of existing or anticipated problems with the acquisition and storage of petroleum products, and future expansion of storage capacity; (6) funds obligated by the Secretary from the SPR Petroleum Account and the Strategic Petroleum Reserve Account during the prior calendar quarter and in total; and (7) major environmental actions completed, in progress, or anticipated.

  7. Ethics and Ethos in Financial Reporting: Analyzing Persuasive Language in Earnings Calls

    ERIC Educational Resources Information Center

    Crawford Camiciottoli, Belinda

    2011-01-01

    In response to ongoing concerns about financial ethics, this study analyzes the speech of company executives in quarterly earnings conference calls to understand strategic usage of ethics-related language. Against the backdrop of the recent global financial crisis, the Aristotelian concept of ethos provides a framework to investigate linguistic…

  8. 12 CFR 741.6 - Financial and statistical and other reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Financial and statistical and other reports... § 741.6 Financial and statistical and other reports. (a) Upon written notice from the Board, Regional... statistical report. Natural person credit unions must file a Call Report with NCUA quarterly in...

  9. 12 CFR 741.6 - Financial and statistical and other reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Financial and statistical and other reports... § 741.6 Financial and statistical and other reports. (a) Upon written notice from the Board, Regional... statistical report. Natural person credit unions must file a Call Report with NCUA quarterly in...

  10. 12 CFR 741.6 - Financial and statistical and other reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Financial and statistical and other reports... § 741.6 Financial and statistical and other reports. (a) Upon written notice from the Board, Regional... statistical report. Natural person credit unions must file a Call Report with NCUA quarterly in...

  11. 45 CFR 237.50 - Recipient count, Federal financial participation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... participation. Pursuant to the formulas in sections 3, 403, 1003, 1118, 1121, 1403, and 1603 of the Social... 45 Public Welfare 2 2010-10-01 2010-10-01 false Recipient count, Federal financial participation... participation. The quarterly statement of expenditures and recoveries which is required for OAA, AFDC, AB,...

  12. 45 CFR 237.50 - Recipient count, Federal financial participation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... participation. Pursuant to the formulas in sections 3, 403, 1003, 1118, 1121, 1403, and 1603 of the Social... 45 Public Welfare 2 2011-10-01 2011-10-01 false Recipient count, Federal financial participation... participation. The quarterly statement of expenditures and recoveries which is required for OAA, AFDC, AB,...

  13. Deployable Crew Quarters

    NASA Technical Reports Server (NTRS)

    Izenson, Michael G.; Chen, Weibo

    2008-01-01

    The deployable crew quarters (DCQ) have been designed for the International Space Station (ISS). Each DCQ would be a relatively inexpensive, deployable boxlike structure that is designed to fit in a rack bay. It is to be occupied by one crewmember to provide privacy and sleeping functions for the crew. A DCQ comprises mostly hard panels, made of a lightweight honeycomb or matrix/fiber material, attached to each other by cloth hinges. Both faces of each panel are covered with a layer of Nomex cloth and noise-suppression material to provide noise isolation from ISS. On Earth, the unit is folded flat and attached to a rigid pallet for transport to the ISS. On the ISS, crewmembers unfold the unit and install it in place, attaching it to ISS structural members by use of soft cords (which also help to isolate noise and vibration). A few hard pieces of equipment (principally, a ventilator and a smoke detector) are shipped separately and installed in the DCQ unit by use of a system of holes, slots, and quarter-turn fasteners. Full-scale tests showed that the time required to install a DCQ unit amounts to tens of minutes. The basic DCQ design could be adapted to terrestrial applications to satisfy requirements for rapid deployable emergency shelters that would be lightweight, portable, and quickly erected. The Temporary Early Sleep Station (TeSS) currently on-orbit is a spin-off of the DCQ.

  14. Understanding Financial Statements. Financial Matters. Board Basics.

    ERIC Educational Resources Information Center

    McCarthy, John H.; Turner, Robert M.

    1998-01-01

    This booklet for trustees of higher education institutions offers guidelines to help trustees understand the institution's financial statements. Individual sections describe the three major financial statements and cover topics such as: (1) standards of the Financial Accounting Standards Board; (2) the "statement of financial position," which…

  15. Anal atresia, coloboma, microphthalmia, and nasal skin tag in a female patient with 3.5 Mb deletion of 3q26 encompassing SOX2.

    PubMed

    Salem, Nabeel J M; Hempel, Maja; Heiliger, Katrin-Janine; Hosie, Stuart; Meitinger, Thomas; Oexle, Konrad

    2013-06-01

    A full term female newborn presented with prominent forehead, bilateral microphthalmia, iris coloboma and cataract, wide intercanthal distance, large, low-set and protruding ears, skin tag at the left nasal nostril, imperforate anus with rectovestibular fistula, and postnatal growth delay with brachymicrocephaly. A marker chromosome was not detectable and the copy number of 22q11 was normal. However, array CGH revealed a 3.5 Mb microdeletion of chromosome region 3q26.32-3q26.33 (chr. 3: 178,598,162-182,114,483; hg19) which comprised the SOX2 gene. While SOX2 haploinsufficiency is known to cause microphthalmia and coloboma, it has not been described before in patients with anal atresia.

  16. Duplication 3q13.11q23: Longitudinal study in a patient over a period of more than 7 years and refinements of the breakpoints.

    PubMed

    Eggermann, Thomas; Spengler, Sabrina; Gamerdinger, Ulrike; Denecke, Bernd; Grimm, Silke; Grimm, Manfred; Schubert, Regine; Schwanitz, Gesa

    2012-06-01

    In 2006, we reported the first case with a pure duplication of proximal 3q. In these rare aberrations, detailed clinical and developmental investigations at different ages are required to provide sufficient phenotypic documentation. Clinical and psychological differences were therefore regularly documented in our case. Supplemental genetic investigations comprised conventional karyotyping, fluorescence in-situ hybridization, single nucleotide polymorphism array analysis, and microsatellite typing. Thus, the exact position and extension of the duplication (3q13.11q23), the size (35.6 Mb), and the paternal origin could be determined. The development of our patient was followed up in detail over a period of 7.5 yr and thus enabled specific characterization of the phenotype of the patient. PMID:27625815

  17. Duplication 3q13.11q23: Longitudinal study in a patient over a period of more than 7 years and refinements of the breakpoints

    PubMed Central

    Eggermann, Thomas; Spengler, Sabrina; Gamerdinger, Ulrike; Denecke, Bernd; Grimm, Silke; Grimm, Manfred; Schubert, Regine; Schwanitz, Gesa

    2012-01-01

    In 2006, we reported the first case with a pure duplication of proximal 3q. In these rare aberrations, detailed clinical and developmental investigations at different ages are required to provide sufficient phenotypic documentation. Clinical and psychological differences were therefore regularly documented in our case. Supplemental genetic investigations comprised conventional karyotyping, fluorescence in-situ hybridization, single nucleotide polymorphism array analysis, and microsatellite typing. Thus, the exact position and extension of the duplication (3q13.11q23), the size (35.6 Mb), and the paternal origin could be determined. The development of our patient was followed up in detail over a period of 7.5 yr and thus enabled specific characterization of the phenotype of the patient.

  18. Financial audit

    SciTech Connect

    Not Available

    1992-01-01

    The Trans-Alaska Pipeline Liability Fund, a nonprofit corporate entity created in 1973, pays claims for damages, including cleanup costs, arising from oil discharges from vessel transporting Trans-Alaska Pipeline System oil loaded at Alaskan terminals to ports under U.S. jurisdiction. This paper presents the results of GAO's view of the independent certified public accountants' audit of the Fund's financial statements as of December 31, 1990. GAO also assesses progress toward disposing of the Fund's balances and terminating the Fund.

  19. 12 CFR 620.11 - Content of quarterly report to shareholders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... shareholders, except that the financial statements included in the quarterly report may be condensed into major... be required to be shown by this subpart with respect to any item is not material, it need not be... material impact on the institution. Disclosures should encompass, for example, significant changes...

  20. 12 CFR 620.11 - Content of quarterly report to shareholders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... shareholders, except that the financial statements included in the quarterly report may be condensed into major... end of the most recent fiscal year that have a material impact on the institution. Disclosures should... shall be included. Furnish any material information necessary to make the information called for...

  1. 12 CFR 620.11 - Content of quarterly report to shareholders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... shareholders, except that the financial statements included in the quarterly report may be condensed into major... be required to be shown by this subpart with respect to any item is not material, it need not be... material impact on the institution. Disclosures should encompass, for example, significant changes...

  2. 78 FR 23903 - Proposed Information Collection; Comment Request; Quarterly Summary of State and Local Government...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... Summary of State and Local Government Tax Revenue provides quarterly estimates of state and local... government tax collections. The Census Bureau needs state and local tax data to publish benchmark statistics... use the data to assess general economic conditions and state and local government financial...

  3. Short-term energy outlook. Quarterly projections, third quarter 1996

    SciTech Connect

    1996-07-01

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in January, April, July, and October in the Outlook. The forecast period for this issue of the Outlook extends from the third quarter of 1996 through the fourth quarter of 1997. Values for the second quarter of 1996, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in the Weekly Petroleum Status Report) or are calculated from model simulations using the latest exogenous information available (for example, electricity sales and generation are simulated using actual weather data). The historical energy data, compiled in the third quarter 1996 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS database is archived quarterly and is available from the National Technical Information Service.

  4. Short-term energy outlook: Quarterly projections. Second quarter 1995

    SciTech Connect

    1995-05-02

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent projections with those of other forecasting services, and discusses current topics related to the short-term energy markets. (See Short-Term Energy Outlook Annual Supplement, DOE/EIA-0202.) The forecast period for this issue of the Outlook extends from the second quarter of 1995 through the fourth quarter of 1996. Values for the first quarter of 1995, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in the Weekly Petroleum Status Report) or are calculated from model simulations using the latest exogenous information available (for example, electricity sales and generation are simulated using actual weather data). The historical energy data, compiled into the second quarter 1995 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS database is archived quarterly and is available from the National Technical Information Service.

  5. Quarterly coal report, July--September 1997

    SciTech Connect

    1998-02-01

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks. Coke production consumption, distribution, imports, and exports data are also provided. This report presents detailed quarterly data for July through September 1997 and aggregated quarterly historical data for 1991 through the second quarter of 1997. Appendix A displays, from 1991 on, detailed quarterly historical coal imports data. 72 tabs.

  6. Evidence for the absence of intron H of the histidine-rich glycoprotein (HRG) gene: Genetic mapping and in situ localization of HRG to chromosome 3q28-q29

    SciTech Connect

    Hennis, B.C.; Poort, E.W. van der; Kluft, C.; Frants, R.R.; Bakker, E.; Vossen, R.H.A.M.; Blonden, L.A.; Khan, P.M. ); Cox, S.; Spurr, N.K. )

    1994-01-01

    Histidine-rich glycoprotein (HRG) belongs to the cystatin superfamily and appears to be a potential risk factor for thrombosis. An increased prevalence of elevated HRG plasma levels in patients with venous thrombosis and families with thrombophilia has been reported. It is interesting to note that the genes of four different members of the cystatin superfamily are located on the distal section of the long arm of chromosome 3: Stefin A (STF1) on 3q21, Kininogen (KNG) on 3q26-qter, [alpha]-2-HS-glycoprotein (AHSG) on 3q27-q28, and HRG on 3q21-qter. To further investigate the evolutionary relationship between HRG and members of the cystatin superfamily, the authors isolated a cosmid that was used to refine the chromosomal localization of HRG by in situ hybridization. In addition, they used a dinucleotide repeat polymorphism to localize HRG on the linkage map of chromosome 3q. 10 refs., 2 figs.

  7. Strategic Petroleum Reserve quarterly report

    SciTech Connect

    1995-11-15

    The Strategic Petroleum Reserve was created pursuant to the Energy Policy and Conservation Act of December 22, 1975 (Public Law 94-163). Its purposes are to reduce the impact of disruptions in supplies of petroleum products and to carry out obligations of the United States under the Agreement on an International Energy Program. Section 165(a) of the Act requires the submission of Annual Reports and Section 165(b)(1) requires the submission of Quarterly Reports. This Quarterly Report highlights activities undertaken during the third quarter of calendar year 1995, including: inventory of petroleum products stored in the Reserve; current storage capacity and ullage available; current status of the Strategic Petroleum Reserve storage facilities, major projects and the acquisition of petroleum products; funds obligated by the Secretary from the SPR Petroleum Account and the Strategic Petroleum Reserve Account during the prior calendar quarter and in total; and major environmental actions completed, in progress, or anticipated.

  8. Quarterly environmental data summary for first quarter 1998

    SciTech Connect

    1998-05-01

    In support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement, a copy of the Quarterly Environmental Data Summary (QEDS) for the first quarter of 1998 is enclosed. The data presented in this letter and attachment constitute the QEDS. The data were received from the contract laboratories, verified by the Weldon Spring Site verification group and, except for air monitoring data and site KPA generated data (uranium analyses), merged into the data base during the first quarter of 1998. Air monitoring data presented are the most recent complete sets of quarterly data. Air data are not stored in the data base, and KPA data are not merged into the regular data base. Significant data, defined as data values that have exceeded defined {open_quotes}above normal{close_quotes} Level 2 values, are discussed in this letter for Environmental Monitoring Plan (EMP) generated data only. Above normal Level 2 values are based, in ES&H procedures, on historical high values, DOE Derived Concentration Guides (DCGs), NPDES limits and other guidelines. The procedures also establish actions to be taken in the event that {open_quotes}above normal{close_quotes} data occur. All data received and verified during the first quarter were within a permissible range of variability except for those detailed below. Above normal occurrences are cited for groundwater, air, and NPDES data. There were none for springs or surface water. The following discussion offers a brief summary of the data merged during the first quarter that exceeded the above normal criteria and updates on past reported above normal data. The attached tables present the most recent data for air and the data merged into the data base during the first quarter 1998 for groundwater, NPDES, surface water, and springs. Graphs showing concentrations of selected contaminants of concern at some of the critical locations have also been included in this QEDS. The graphs are discussed in the separate sections.

  9. Intersectoral interagency partnerships to promote financial capability in older people.

    PubMed

    Hean, Sarah; Fenge, Lee Ann; Worswick, Louise; Wilkinson, Charlie; Fearnley, Stella

    2012-09-01

    From the second quarter of 2008, the UK economy entered a period of economic decline. Older people are particularly vulnerable during these times. To promote ways in which older people can be better supported to maintain their financial well-being, this study explored the sources older people utilize to keep themselves financially informed. Interviews with older people (n = 28) showed that older people access trusted sources of information (e.g. healthcare professionals) rather than specialist financial information providers (e.g. financial advisors) which highlighted the need for interagency working between financial services in the private, public and voluntary sectors. An example of how such interagency partnerships might be achieved in practice is presented with some recommendations on directions for future research into interagency working that spans public, private and voluntary sectors.

  10. Short-term energy outlook: Quarterly projections, fourth quarter 1997

    SciTech Connect

    1997-10-14

    The Energy Information Administration (EIA) prepares quarterly short-term energy supply, demand, and price projections for printed publication in January, April, July, and October in the Short-Term Energy Outlook. The details of these projections, as well as monthly updates on or about the 6th of each interim month, are available on the internet at: www.eia.doe.gov/emeu/steo/pub/contents.html. The forecast period for this issue of the Outlook extends from the fourth quarter of 1997 through the fourth quarter of 1998. Values for the fourth quarter of 1997, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in EIA`s Weekly Petroleum Status Report) or are calculated from model simulations that use the latest exogenous information available (for example, electricity sales and generation are simulated by using actual weather data). The historical energy data, compiled in the fourth quarter 1997 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS model is driven principally by three sets of assumptions or inputs: estimates of key macroeconomic variables, world oil price assumptions, and assumptions about the severity of weather. 19 tabs.

  11. Quarterly environmental data summary for fourth quarter 1997

    SciTech Connect

    1997-12-31

    The Quarterly Environmental Data Summary (QEDS) for the fourth quarter of 1997 is prepared in support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement. The data presented constitute the QEDS. The data were received from the contract laboratories, verified by the Weldon Spring Site verification group and, except for air monitoring data and site KPA generated data (uranium analyses), merged into the data base during the fourth quarter of 1997. Air monitoring data presented are the most recent complete sets of quarterly data. Air data are not stored in the data base and KPA data are not merged into the regular data base. Significant data, defined as data values that have exceeded defined ``above normal`` level 2 values, are discussed in this letter for Environmental Monitoring Plan (EMP) generated data only. Above normal level 2 values are based, in ES and H procedures, on historical high values, DOE Derived Concentration Guides (DCGs), NPDES limits and other guidelines. The procedures also establish actions to be taken in response to such data. Data received and verified during the fourth quarter were within a permissible range of variability except for those which are detailed.

  12. Strategic Petroleum Reserve. Quarterly report

    SciTech Connect

    Not Available

    1993-11-15

    The Strategic Petroleum Reserve serves as one of the most important investments in reducing the Nation`s vulnerability to oil supply disruptions. This Quarterly Report highlights activities undertaken during the third quarter of calendar year 1993, including: inventory of petroleum products stored in the Reserve, under contract and in transit at the end of the calendar quarter; fill rate for the quarter and projected fill rate for the next calendar quarter; average price of the petroleum products acquired during the calendar quarter; current and projected storage capacity and plans to accelerate the acquisition or construction of such capacity; analysis of existing or anticipated problems with the acquisition and storage of petroleum products and future expansion of storage capacity; funds obligated by the Secretary from the SPR Petroleum Account and the Strategic Petroleum Reserve Account during the prior calendar quarter and in total; and major environmental actions completed, in progress, or anticipated. Samples of the oil revealed two problems that, although readily correctable, have reduced the availability of some of the oil inventory for drawdown in the near-term. These problems are: (1) a higher-than-normal gas content in some of the crude oil, apparently from years of intrusion of methane form the surrounding salt formation; and (2) elevated temperatures of some of the crude oil, due to geothermal heating, that has increased the vapor pressure of the oil. Investigations are proceeding to determine the extent to which gas intrusion and geothermal heating are impacting the availability of oil for drawdown. Preliminary designs have been developed for systems to mitigate both problems.

  13. EVI1, a target gene for amplification at 3q26, antagonizes transforming growth factor-β-mediated growth inhibition in hepatocellular carcinoma.

    PubMed

    Yasui, Kohichiroh; Konishi, Chika; Gen, Yasuyuki; Endo, Mio; Dohi, Osamu; Tomie, Akira; Kitaichi, Tomoko; Yamada, Nobuhisa; Iwai, Naoto; Nishikawa, Taichiro; Yamaguchi, Kanji; Moriguchi, Michihisa; Sumida, Yoshio; Mitsuyoshi, Hironori; Tanaka, Shinji; Arii, Shigeki; Itoh, Yoshito

    2015-07-01

    EVI1 (ecotropic viral integration site 1) is one of the most aggressive oncogenes associated with myeloid leukemia. We investigated DNA copy number aberrations in human hepatocellular carcinoma (HCC) cell lines using a high-density oligonucleotide microarray. We found that a novel amplification at the chromosomal region 3q26 occurs in the HCC cell line JHH-1, and that MECOM (MDS1 and EVI1 complex locus), which lies within the 3q26 region, was amplified. Quantitative PCR analysis of the three transcripts transcribed from MECOM indicated that only EVI1, but not the fusion transcript MDS1-EVI1 or MDS1, was overexpressed in JHH-1 cells and was significantly upregulated in 22 (61%) of 36 primary HCC tumors when compared with their non-tumorous counterparts. A copy number gain of EVI1 was observed in 24 (36%) of 66 primary HCC tumors. High EVI1 expression was significantly associated with larger tumor size and higher level of des-γ-carboxy prothrombin, a tumor marker for HCC. Knockdown of EVI1 resulted in increased induction of the cyclin-dependent kinase inhibitor p15(INK) (4B) by transforming growth factor (TGF)-β and decreased expression of c-Myc, cyclin D1, and phosphorylated Rb in TGF-β-treated cells. Consequently, knockdown of EVI1 led to reduced DNA synthesis and cell viability. Collectively, our results suggest that EVI1 is a probable target gene that acts as a driving force for the amplification at 3q26 in HCC and that the oncoprotein EVI1 antagonizes TGF-β-mediated growth inhibition of HCC cells.

  14. A 4-Mb deletion in the region Xq27.3-q28 is associated with non-random inactivation of the non-mutant X chromosome

    SciTech Connect

    Clarke, J.T.R.; Han, L.P.; Michalickova, K.

    1994-09-01

    A girl with severe Hunter disease was found to have a submicroscopic deletion distrupting the IDS locus in the region Xq27.3-q28 together with non-random inactivation of the non-mutant X chromosome. Southern analysis of DNA from the parents and from hamster-patient somatic cell hybrids containing only the mutant X chromosome revealed that the deletion represented a de novo mutation involving the paternal X chromosome. Methylation-sensitive RFLP analysis of DNA from maternal fibroblasts and lymphocytes showed methylation patterns consistent with random X-inactivation, indicating that the non-random X-inactivation in the patient was not inherited and was likely a direct result of the Xq27.3-q28 deletion. A 15 kb EcoRI junction fragment, identified in patient DNA using IDS cDNA probes, was cloned from a size-selected patient DNA library. Clones containing the deletion junction were restriction mapped and fragments were subcloned and used to isolate normal sequence on either side of the deletion from normal X chromosome libraries. Comparison of the sequences from normal and mutant X chromosome clones straddling the deletion breakpoint showed that the mutation had occurred by recombination between Alu repeats. Screening of YAC contigs containing normal X chromosome sequence from the region of the mutation, using probes from either side of the deletion breakpoint, showed that the deletion was approximately 4 Mb in size. Probing of mutant DNA with 16 STSs distributed throughout the region of the deletion confirmed that the mutation is a simple deletion with no complex rearrangements of islands of retained DNA. A search for sequences at Xq27.3-q28 involved in X chromosome inactivation is in progress.

  15. Quarterly coal report, April--June 1997

    SciTech Connect

    1997-11-01

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience. Coke production, consumption, distribution, imports, and exports data are also provided. This report presents detailed quarterly data for April through June 1997 and aggregated quarterly historical data for 1991 through the first quarter of 1997. Appendix A displays, from 1991 on, detailed quarterly historical coal imports data. Appendix B gives selected quarterly tables converted to metric tons. To provide a complete picture of coal supply and demand in the US, historical information has been integrated in this report. 8 figs., 73 tabs.

  16. Mental retardation/shortness of stature/multiple minor anomalies syndrome associated with insertion of 3q material into 18p

    SciTech Connect

    Al-Attia, H.M.; Sedaghatian, M.R.

    1995-03-13

    This is a case report of a 16-year-old Arab girl with mental subnormality, shortness of stature and multiple minor phenotypic anomalies. She is obese with normal secondary sexual characteristics, and has a speech deficit. Cytogenetic studies showed a 46,XX,dir ins (18;3)(p11.1;q13.2{yields}q25). The chromosome arrangement appeared balanced. Her condition is not a recognizable specific syndrome; thus, it remained unclear as to whether her condition is attributable to disruption of 3q or 18p or both. Further cytogenetic analysis by molecular biologists is required to solve this problem. 9 refs., 3 figs.

  17. Short-term energy outlook. Quarterly projections, first quarter 1996

    SciTech Connect

    1996-02-01

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Outlook. The forecast period for this issue of the Outlook extends from the first quarter of 1996 through the fourth quarter of 1997. Values for the fourth quarter of 1995, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in the Weekly Petroleum Status Report) or are calculated from model simulations using the latest exogenous information available (for example, electricity sales and generation are simulated using actual weather data). The historical energy data, compiled into the first quarter 1996 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS database is archived quarterly and is available from the National Technical Information Service. The cases are produced using the Short-Term Integrated Forecasting System (STIFS). The STIFS model is driven principally by three sets of assumptions or inputs: estimates of key macroeconomic variables, world oil price assumptions, and assumptions about the severity of weather. Macroeconomic estimates are produced by DRI/McGraw-Hill but are adjusted by EIA to reflect EIA assumptions about the world price of crude oil, energy product prices, and other assumptions which may affect the macroeconomic outlook.

  18. Short-term energy outlook: Quarterly projections, second quarter 1997

    SciTech Connect

    1997-04-01

    The Energy Information Administration (EIA) prepares quarterly short-term energy supply, demand, and price projections for publication in January, April, July, and October in the Outlook. The forecast period for this issue of the Outlook extends from the second quarter of 1997 through the fourth quarter of 1998. Values for the first quarter of 1997, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in EIA`s Weekly Petroleum Status Report) or are calculated from model simulations that use the latest exogenous information available (for example, electricity sales and generation are simulated by using actual weather data). The historical energy data, compiled in the second quarter 1997 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS database is archived quarterly and is available from the National Technical Information Service. The STIFS model is driven principally by three sets of assumptions or inputs: estimates of key macroeconomic variables, world oil price assumptions, and assumptions about the severity of weather. Macroeconomic estimates are produced by DRI/McGraw-Hill but are adjusted by EIA to reflect EIA assumptions about the world price of crude oil, energy product prices, and other assumptions which may affect the macroeconomic outlook. By varying the assumptions, alternative cases are produced by using the Short-Term Integrated Forecasting System (STIFS). 34 figs., 19 tabs.

  19. UNOCAL Parachute Creek Shale Oil Program. Environmental monitoring plan quarterly report. Second quarter 1988. Report for 1 April-30 June 1988

    SciTech Connect

    Not Available

    1988-08-31

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commercial-scale synthetic fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The support agreement included development of an Environmental Monitoring Plan incorporating existing compliance monitoring and supplemental monitoring on water, air, solid waste, worker health and safety, and socio-economic impacts during the period 1986-1993. Twenty-two supplemental monitoring sites have been designated, to date. The report includes compliance operational monitoring data, ambient and source compliance data collected the previous quarter, and results of the industrial hygiene monitoring during the first quarter, 1988. Four pages of text precede over 718 pages of data sheets.

  20. Unocal Parachute Creek Shale Oil Program. Environmental Monitoring Plan quarterly report. Fourth quarter, 1989. Rept. for 1 Oct-31 Dec 89

    SciTech Connect

    Not Available

    1990-02-28

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commerical-scale synthetic fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The Program agreed to comply with existing environmental monitoring regulations and to develop an Environmental Monitoring Plan incorporating supplemental monitoring in the areas of water, air, solid waste, and worker health and safety during the period 1985-1992. These activities are described in a series of quarterly and annual reports. The report contains environmental compliance data reports, results of industrial hygiene compliance monitoring, and independent audits. Table 2-1 shows 14 of the 20 supplemental monitoring sites sampled during the quarter.

  1. Third case of 8q23.3-q24.13 deletion in a patient with Langer-Giedion syndrome phenotype without TRPS1 gene deletion.

    PubMed

    Pereza, Nina; Severinski, Srećko; Ostojić, Saša; Volk, Marija; Maver, Aleš; Dekanić, Kristina Baraba; Kapović, Miljenko; Peterlin, Borut

    2012-03-01

    Langer-Giedion syndrome (LGS) is a contiguous gene syndrome caused by a hemizygous deletion on chromosome 8q23.3-q24.11 involving TRPS1 and EXT1 genes. We report on a girl with LGS phenotype and a 7.5 Mb interstitial deletion at chromosome 8q23.3-q24.13. Array-comparative genomic hybridization (a-CGH) revealed a deletion encompassing only the EXT1 and not the TRPS1 gene. Even though the deletion of TRPS1 and EXT1 genes is responsible for craniofacial and skeletal features of LGS, there have been previous reports of patients with LGS phenotype and 8q24 deletions leaving the TRPS1 gene intact. To our knowledge, this is the third such case. Our patient differs from previously reported LGS patients without TRPS1 gene deletion in that she has the typical LGS facial dysmorphism and skeletal abnormalities. However, the girl is of normal height and has only a mild developmental delay. Additionally, she has dyslalia and premature adrenarche classified as Tanner stage 3 premature pubarche which have not yet been described as features of LGS. We examine the molecular breakpoints and phenotypes of our patient and previously reported cases.

  2. Acute myeloid leukemia presenting in a mother and daughter pair with the identical acquired karyotypic abnormality consisting of inversion 3q21q26 and monosomy 7: a review of possible mechanisms.

    PubMed

    Lawrie, Alastair; Stevenson, David A J; Doig, Tamasin N; Vickers, Mark A; Culligan, Dominic J

    2012-11-01

    The 3q21q26 inversion is associated with both myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), often in association with monosomy 7. In this report, we present a young woman and her mother, both diagnosed with AML, exhibiting similar morphological and identical cytogenetic features. AML with abnormalities of chromosome 3q is often characterized by abnormal megakaryopoeisis and diabetes insipidus, and both were seen in these cases. To our knowledge, this is the first report of familial aggregation of AML displaying an inversion of chromosome 3q and monosomy 7. We discuss possible mechanisms for the development of familial AML with identical karyotypic abnormalities and the link between 3q aberrations and monosomy 7.

  3. Short-term energy outlook, quarterly projections, first quarter 1998

    SciTech Connect

    1998-01-01

    The forecast period for this issue of the Outlook extends from the first quarter of 1998 through the fourth quarter of 1999. Values for the fourth quarter of 1997, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in EIA`s Weekly Petroleum Status Report) or are calculated from model simulations that use the latest exogenous information available (for example, electricity sales and generation are simulated by using actual weather data). The historical energy data, compiled in the first quarter 1998 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS model is driven principally by three sets of assumptions or inputs: estimates of key macroeconomic variables, world oil price assumptions, and assumptions about the severity of weather. Macroeconomic estimates are adjusted by EIA to reflect EIA assumptions which may affect the macroeconomic outlook. By varying the assumptions, alternative cases are produced by using the STIFS model. 24 figs., 19 tabs.

  4. Short-term energy outlook quarterly projections. First quarter 1994

    SciTech Connect

    Not Available

    1994-02-07

    The Energy Information Administration (EIA) prepares quarterly, short- term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent cases with those of other forecasting services, and discusses current topics related to the short-term energy markets.

  5. Applied Meteorology Unit (AMU) Quarterly Report First Quarter FY-04

    NASA Technical Reports Server (NTRS)

    Bauman, William; Wheeler, Mark; Labert, Winifred; Jonathan Case; Short, David

    2004-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the First Quarter of Fiscal Year 2004 (October - December 2003). Tasks reviewed are: (1) Objective Lightning Probability Forecast, (2) Mesonet Temperature and Wind Climatology, (3) Severe Weather Forecast Decision Aid and (4) Anvil Transparency Relationship to Radar Reflectivity

  6. Short-term energy outlook, Quarterly projections. Third quarter 1993

    SciTech Connect

    1993-08-04

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent cases with those of other forecasting services, and discusses current topics related to the short-term energy markets. (See Short-Term Energy Outlook Annual Supplement, DOE/EIA-0202.) The forecast period for this issue of the Outlook extends from the third quarter of 1993 through the fourth quarter of 1994. Values for the second quarter of 1993, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in the Weekly Petroleum Status Report) or are calculated from model simulations using the latest exogenous information available (for example, electricity sales and generation are simulated using actual weather data). The historical energy data are EIA data published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding.

  7. Short-Term Energy Outlook: Quarterly projections. Fourth quarter 1993

    SciTech Connect

    Not Available

    1993-11-05

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent cases with those of other forecasting services, and discusses current topics related to the short-term energy markets. (See Short-Term Energy Outlook Annual Supplement, DOE/EIA-0202.) The forecast period for this issue of the Outlook extends from the fourth quarter of 1993 through the fourth quarter of 1994. Values for the third quarter of 1993, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in the Weekly Petroleum Status Report) or are calculated from model simulations using the latest exogenous information available (for example, electricity sales and generation are simulated using actual weather data). The historical energy data are EIA data published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications.

  8. Equine Disease Surveillance: Quarterly Summary.

    PubMed

    2016-01-23

    West Nile virus in Europe and the USA. Evidence that the spread of vesicular stomatitis in the USA is beginning to slow. Summary of UK surveillance testing, July to September 2015 These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association. PMID:26795859

  9. Gifted Education Press Quarterly, 2001.

    ERIC Educational Resources Information Center

    Fisher, Maurice D., Ed.

    2001-01-01

    These four issues of this quarterly publication on the education of gifted students contain the following featured articles: (1) "Reflections on China: Implications for Gifted Education" (Andrea I. Prejean and Lynn H. Fox); (2) "Differentiating Instruction for Gifted Middle School Students in Heterogeneous Science Classes" (Brendan D. Miller and…

  10. Apprentices & Trainees: September Quarter, 2012

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2013

    2013-01-01

    This publication presents estimates of apprentice and trainee activity in Australia for the September quarter 2012. The figures in this publication are derived from the National Apprentice and Trainee Collection no.74 (December 2012 estimates). The most recent figures in this publication are estimated (those for training activity from the March…

  11. Gifted Education Press Quarterly, 2000.

    ERIC Educational Resources Information Center

    Fisher, Maurice D., Ed.

    2000-01-01

    Four issues of this quarterly publications on gifted education include the following articles: "Unrecognized Giftedness: The Frustrating Case of the Gifted Adult" (Marylou Kelly Streznewski); "Shakespeare in the Classroom: The Bard is Back!" (Rosanna DiMillo Sandell); "What Teachers, Parents, and Administrators Need To Know about Gifted Students"…

  12. Trustee Quarterly, 2000-2001.

    ERIC Educational Resources Information Center

    Trustee Quarterly, 2001

    2001-01-01

    This document contains 4 issues of the Trustee Quarterly: fall 2000, spring 2001, summer 2001, and fall 2001. The fall 2000 issue contains seven features and six departments. Among the features are: "The New Economy: Who Will Lead the Education Movement," by Rucker; "Community Colleges Tackle IT Staffing Challenges," by Matina; and "Looking at…

  13. Strategic petroleum reserve. Quarterly report

    SciTech Connect

    1995-08-15

    The Strategic Petroleum Reserve reduces the Nation`s vulnerability to oil supply disruptions. Its existence provides a formidable deterrent to the use of oil as a political instrument and an effective response mechanism should a disruption occur. The Strategic Petroleum Reserve was created pursuant to the Energy Policy and Conservation Act of December 22, 1975 (Public Law 94-163). Its purposes are to reduce the impact of disruptions in supplies of petroleum products and to carry out obligations of the United States under the Agreement on an International Energy Program. Section 165(a) of the Act requires the submission of Annual Reports and Section 165(b)(1) requires the submission of Quarterly Reports. This Quarterly Report highlights activities undertaken during the second quarter of calendar year 1995, including: inventory of petroleum products stored in the Reserve; current and projected storage capacity, analysis of existing or anticipated problems with the acquisition and storage of petroleum products, and future expansion of storage capacity; funds obligated by the Secretary from the SPR Petroleum Account and the Strategic Petroleum Reserve Account during the prior calendar quarter and in total; and major environmental actions completed, in progress, or anticipated.

  14. Gifted Education Press Quarterly, 1999.

    ERIC Educational Resources Information Center

    Fisher, Maurice D., Ed.

    1999-01-01

    This document consists of the four 1999 issues of a quarterly newsletter publication on gifted education. Issues regularly include major articles, book reviews, announcements, and letters. The major articles in these issues are: "The Mathematically Gifted: Bridging the Gender Gap" (Lynn H. Fox and Janet F. Soller); "Parenting for Education:…

  15. Space Station Quarterly, May 1992

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This quarterly report discusses the First International Microgravity Laboratory, the building of space station truss structures at the Johnson Space Center, the building of the living and laboratory modules at the Marshall Space Flight Center, and the Lewis Research Center's work on power for the space station. The video includes a segment on the Japanese Experiment Module.

  16. Education Statistics Quarterly, Spring 2001.

    ERIC Educational Resources Information Center

    Education Statistics Quarterly, 2001

    2001-01-01

    The "Education Statistics Quarterly" gives a comprehensive overview of work done across all parts of the National Center for Education Statistics (NCES). Each issue contains short publications, summaries, and descriptions that cover all NCES publications, data products and funding opportunities developed over a 3-month period. Each issue also…

  17. Gifted Education Press Quarterly, 1995.

    ERIC Educational Resources Information Center

    Fisher, Maurice D., Ed.

    1995-01-01

    This document consists of the four issues of the newsletter "Gifted Education Press Quarterly" published during 1995. This newsletter addresses issues in the education of gifted children and youth. The major articles are: (1) "Using Today's Technology: Parents Can Help Challenge Gifted Children" (Adrienne O'Neill); (2) "Outcomes-Based Education…

  18. Gifted Education Press Quarterly, 2002.

    ERIC Educational Resources Information Center

    Fisher, Maurice D., Ed.

    2002-01-01

    These four issues of a quarterly publication for gifted educators and parents of gifted children span winter 2002 through fall 2002. Featured articles include: (1) "Cultivating Courage, Creativity, and Caring" (James T. Webb), which discusses the need to encourage the development of courage and caring, as well as creativity in gifted students; (2)…

  19. Education Statistics Quarterly, Fall 2000.

    ERIC Educational Resources Information Center

    Dillow, Sally, Ed.

    2000-01-01

    The "Education Statistics Quarterly" gives a comprehensive overview of work done across all parts of the National Center for Education Statistics (NCES). Each issue contains short publications, summaries, and descriptions that cover all NCES publications and data products released during a 3-month period. Each message also contains a message from…

  20. JLTN Quarterly, 1995-1996.

    ERIC Educational Resources Information Center

    JLTN Quarterly, 1996

    1996-01-01

    This document consists of the four issues of the "JLTN Quarterly" issued from December 1995 to October 1996. This journal for high school Japanese language teachers contain articles on class activities and classroom teaching techniques. These include: exercises in interpretation of a Toys "R" Us store map and advertising; a weather discussion…

  1. Quarterly coal report, October--December 1996

    SciTech Connect

    1997-05-01

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. This report presents detailed quarterly data for October through December 1996 and aggregated quarterly historical data for 1990 through the third quarter of 1996. Appendix A displays, from 1988 on, detailed quarterly historical coal imports data. To provide a complete picture of coal supply and demand in the US, historical information has been integrated in this report. 8 figs., 72 tabs.

  2. Renewable Energy Finance Tracking Initiative (REFTI): Snapshot of Recent Geothermal Financing Terms, Fourth Quarter 2009 - Second Half 2011

    SciTech Connect

    Lowder, T.; Hubbell, R.; Mendelsohn, M.; Cory, K.

    2012-09-01

    This report is a review of geothermal project financial terms as reported in the National Renewable Energy Laboratory's Renewable Energy Finance Tracking Initiative (REFTI). The data were collected over seven analysis periods from the fourth quarter (Q4) of 2009 to the second half (2H) of 2011.

  3. 3Q/4Q00 Annual M-Area and Metallurgical Laboratory Hazardous Waste Management Facilities Groundwater Monitoring and Corrective-Action Report - Third and Fourth Quarters 2000 - Volumes I, II, and II

    SciTech Connect

    Cole, C.M. Sr.

    2001-04-17

    This report describes the groundwater monitoring and corrective-action program at the M-Area Hazardous Waste Management Facility (HWMF) and the Metallurgical Laboratory (Met Lab) HWMF at the Savannah River Site (SRS) during 2000. This program is required by South Carolina Resource Conservation and Recovery Act (RCRA) Hazardous Waste Permit SC1890008989 and Section 264.100(g) of the South Carolina Hazardous Waste Management Regulations.

  4. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

    PubMed Central

    Broderick, Peter; Chen, Bowang; Johnson, David C; Försti, Asta; Vijayakrishnan, Jayaram; Migliorini, Gabriele; Dobbins, Sara E; Holroyd, Amy; Hose, Dirk; Walker, Brian A; Davies, Faith E; Gregory, Walter A; Jackson, Graham H; Irving, Julie A; Pratt, Guy; Fegan, Chris; Fenton, James AL; Neben, Kai; Hoffmann, Per; Nöthen, Markus M; Mühleisen, Thomas W; Eisele, Lewin; Ross, Fiona M; Straka, Christian; Einsele, Hermann; Langer, Christian; Dörner, Elisabeth; Allan, James M; Jauch, Anna; Morgan, Gareth J; Hemminki, Kari; Houlston, Richard S; Goldschmidt, Hartmut

    2016-01-01

    To identify variants for multiple myeloma risk, we conducted a genome-wide association study with validation in additional series totaling 4,692 cases and 10,990 controls. We identified four risk loci at 3q26.2 (rs10936599, P=8.70x10-14), 6p21.33 (rs2285803, PSORS1C2; P= 9.67x10-11), 17p11.2 (rs4273077, TNFRSF13B; P=7.67x10-9) and 22q13.1 (rs877529, CBX7; P=7.63x10-16). These data provide further evidence for genetic susceptibility to this B-cell hematological malignancy and insight into the biological basis of predisposition. PMID:23955597

  5. Develop the dual fuel conversion system for high output, medium speed diesel engines. Quarterly report number 1, September 1--December 31, 1996

    SciTech Connect

    1997-01-08

    Energy Conversions Incorporated has made substantial progress on the EMD-710 dual-fuel test cell in the first quarter of the project. The project is on schedule and has not met with any major roadblocks that would derail the planned timetable. Please note that much of the work done started before the funding arrived, and therefore those items are not included in the financial expenditures for the quarter.

  6. Financial Responsibilities. Financial Matters. Board Basics.

    ERIC Educational Resources Information Center

    Burlock, Tracy J.; Chabotar, Kent John

    1998-01-01

    This booklet for trustees of institutions of higher education offers guidelines to enable trustees to fulfill their fundamental responsibility of ensuring the financial health of the institution. Introductory sections address: challenges of the financial environment in which trustees must make decisions; specific responsibilities of the…

  7. Financial exploitation, financial capacity, and Alzheimer's disease.

    PubMed

    Lichtenberg, Peter A

    2016-01-01

    Research in the past decade has documented that financial exploitation of older adults has become a major problem, and psychology is only recently increasing its presence in efforts to reduce exploitation. During the same time period, psychology has been a leader in setting best practices for the assessment of diminished capacity in older adults culminating in the 2008 American Bar Association Commission on Law and Aging and American Psychological Association (ABA/APA) joint publication on a handbook for psychologists. Assessment of financial decision-making capacity is often the cornerstone assessment needed in cases of financial exploitation. This article will examine the intersection of financial exploitation and decision-making capacity and introduce a new conceptual model and new tools for both the investigation and prevention of financial exploitation. (PsycINFO Database Record PMID:27159438

  8. Financial exploitation, financial capacity, and Alzheimer's disease.

    PubMed

    Lichtenberg, Peter A

    2016-01-01

    Research in the past decade has documented that financial exploitation of older adults has become a major problem, and psychology is only recently increasing its presence in efforts to reduce exploitation. During the same time period, psychology has been a leader in setting best practices for the assessment of diminished capacity in older adults culminating in the 2008 American Bar Association Commission on Law and Aging and American Psychological Association (ABA/APA) joint publication on a handbook for psychologists. Assessment of financial decision-making capacity is often the cornerstone assessment needed in cases of financial exploitation. This article will examine the intersection of financial exploitation and decision-making capacity and introduce a new conceptual model and new tools for both the investigation and prevention of financial exploitation. (PsycINFO Database Record

  9. Applied Meteorology Unit (AMU) Quarterly Report Fourth Quarter FY-04

    NASA Technical Reports Server (NTRS)

    Bauman, William; Wheeler, Mark; Lambert, Winifred; Case, Jonathan; Short, David

    2004-01-01

    This report summarizes the Applied Meteorology Unit (A MU) activities for the fourth quarter of Fiscal Year 2004 (July -Sept 2004). Tasks covered are: (1) Objective Lightning Probability Forecast: Phase I, (2) Severe Weather Forecast Decision Aid, (3) Hail Index, (4) Shuttle Ascent Camera Cloud Obstruction Forecast, (5) Advanced Regional Prediction System (ARPS) Optimization and Training Extension and (5) User Control Interface for ARPS Data Analysis System (ADAS) Data Ingest.

  10. Renewable Energy Project Financing: Impacts of the Financial Crisis and Federal Legislation

    SciTech Connect

    Schwabe, P.; Cory, K.; Newcomb, J.

    2009-07-01

    Extraordinary financial market conditions have disrupted the flows of equity and debt investment into U.S. renewable energy (RE) projects since the fourth quarter of 2008. The pace and structure of renewable energy project finance has been reshaped by a combination of forces, including the financial crisis, global economic recession, and major changes in federal legislation affecting renewable energy finance. This report explores the impacts of these key market events on renewable energy project financing and development.

  11. Land application uses of dry FGD by-products: Quarterly report, October--December 1994

    SciTech Connect

    Beeghly, J.H.; Dick, W.A.; Haefner, R.J.

    1995-02-01

    The project involves the testing of several ground application uses for flue gas desulfurization by-products, including the mitigation of acid mine drainage, agronomic liming, cattle feedlot, stabilization of coal refuse, and road embankments. The project also involves ground water monitoring, environmental modeling, and economic modeling. This quarterly report deals mostly with the financial aspects of the research project. Monthly progress reports from various sites are included.

  12. Financial Advice: Who Pays

    ERIC Educational Resources Information Center

    Finke, Michael S.; Huston, Sandra J.; Winchester, Danielle D.

    2011-01-01

    Using a cost-benefit framework for financial planning services and proprietary data collected in the summer of 2008, the client characteristics that are associated with the likelihood of paying for professional financial advice, as well as the type of financial services purchased, are identified. Results indicate that respondents who pay for…

  13. Invest in Financial Literacy

    ERIC Educational Resources Information Center

    Bush, Sarah B.; McGatha, Maggie B.; Bay-Williams, Jennifer M.

    2012-01-01

    The current state of the economy elevates the need to build awareness of financial markets and personal finance among the nation's young people through implementing a financial literacy curriculum in schools. A limited amount of time spent on financial literacy can have a positive effect on students' budgeting skills. This knowledge will only add…

  14. Crew quarters for Space Station

    NASA Technical Reports Server (NTRS)

    Mount, F. E.

    1989-01-01

    The only long-term U.S. manned space mission completed has been Skylab, which has similarities as well as differences to the proposed Space Station. With the exception of Skylab missions, there has been a dearth of experience on which to base the design of the individual Space Station Freedom crew quarters. Shuttle missions commonly do not have sleep compartments, only 'sleeping arrangements'. There are provisions made for each crewmember to have a sleep restraint and a sleep liner, which are attached to a bulkhead or a locker. When the Shuttle flights began to have more than one working shift, crew quarters became necessary due to noise and other disturbances caused by crew task-related activities. Shuttle missions that have planned work shifts have incorporated sleep compartments. To assist in gaining more information and insight for the design of the crew quarters for the Space Station Freedom, a survey was given to current crewmembers with flight experience. The results from this survey were compiled and integrated with information from the literature covering space experience, privacy, and human-factors issues.

  15. Strategic Petroleum Reserve quarterly report

    SciTech Connect

    Not Available

    1992-08-15

    The Strategic Petroleum Reserve (SPR) was created pursuant to the Energy Policy and Conservation Act (EPCA) Public Law 94-163, approved on December 22, 1975, and extended in July 1985, June 1989, March 1990, and September 1990, to reduce the impact of disroptions in petroleum supplies and to carry out obligations of the United States under the Agreement on an International Energy Program. The Strategic Petroleum Reserve Quarterly Report is submitted in accordance with section 165(b) of the Energy Policy and Conservation Act, as amended, which requires that the Secretary of Energy submit quarterly reports to Congress on activities undertaken with respect to the Strategic Petroleum Reserve. Since the Strategic Petroleum Reserve crude oil storage facilities program for the 750 minion barrels was completed in 1991, this August 15, 1992, Strategic Petroleum Reserve Quarterly Report focuses on activities related primarily to the storage facilities status, oil acquisition, budget, and cost of the Reserve during the period April 1, 1992, through June 30, 1992.

  16. Female patient with autistic disorder, intellectual disability, and co-morbid anxiety disorder: Expanding the phenotype associated with the recurrent 3q13.2-q13.31 microdeletion.

    PubMed

    Quintela, Ines; Gomez-Guerrero, Lorena; Fernandez-Prieto, Montse; Resches, Mariela; Barros, Francisco; Carracedo, Angel

    2015-12-01

    In recent years, the advent of comparative genomic hybridization (CGH) and single nucleotide polymorphism (SNP) arrays and its use as a first genetic test for the diagnosis of patients with neurodevelopmental phenotypes has allowed the identification of novel submicroscopic chromosomal abnormalities (namely, copy number variants or CNVs), imperceptible by conventional cytogenetic techniques. The 3q13.31 microdeletion syndrome (OMIM #615433) has been defined as a genomic disorder mainly characterized by developmental delay, postnatal overgrowth, hypotonia, genital abnormalities in males, and characteristic craniofacial features. Although the 3q13.31 CNVs are variable in size, a 3.4 Mb recurrently altered region at 3q13.2-q13.31 has been recently described and non-allelic homologous recombination (NAHR) mediated by flanking human endogenous retrovirus (HERV-H) elements has been suggested as the mechanism of deletion formation. We expand the phenotypic spectrum associated with this recurrent deletion performing the clinical description of a 9-year-old female patient with autistic disorder, total absence of language, intellectual disability, anxiety disorder and disruptive, and compulsive eating behaviors. The array-based molecular karyotyping allowed the identification of a de novo recurrent 3q13.2-q13.31 deletion encompassing 25 genes. In addition, we compare her clinical phenotype with previous reports of patients with neurodevelopmental and behavioral disorders and proximal 3q microdeletions. Finally, we also review the candidate genes proposed so far for these phenotypes.

  17. CD28/CTLA-4 ligands: the gene encoding CD86 (B70/B7.2) maps to the same region as CD80 (B7/B7.1) gene in human chromosome 3q13-q23.

    PubMed

    Fernández-Ruiz, E; Somoza, C; Sánchez-Madrid, F; Lanier, L L

    1995-05-01

    CD86 (B70/B7.2) is an antigen of the immunoglobulin superfamily expressed on monocytes, dendritic cells and activated B, T, and natural killer cells. CD86 was recently identified as a second ligand for the T cell antigens CD28 and CTLA-4, and plays an important role in the co-stimulation of T cells in a primary immune response. We report here the assignment of the CD86 gene to human chromosome 3 using Southern blot analysis on a panel of hamster x human somatic cell hybrid genomic DNA. Fluorescence hybridization in situ on metaphase chromosomes coupled with GTG banding (G-bands by trypsin using Giemsa staining) confirmed this assignment and localized the CD86 gene to 3q13-q23 region. The CD86 gene is, therefore, located in the proximity of the CD80 (B7/B7.1) gene, the first identified ligand for CD28 and CTLA-4, previously mapped to chromosome 3q13.3-q21. Deletions, inversions and insertions of chromosome 3q21-q26, as well as translocations of 3q21 with other chromosomes have been described in many cases of acute myeloid leukemia (AML), acute non-lymphocytic leukemia (ANLL), chronic myeloid leukemia (CML) and myelodisplastic syndromes (MDS), suggesting that this region contains several genes involved in the leukemic process.

  18. Quarterly coal report, October--December 1994

    SciTech Connect

    1995-05-23

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended. This report presents detailed quarterly data for October through December 1994 and aggregated quarterly historical data for 1986 through the third quarter of 1994. Appendix A displays, from 1986 on, detailed quarterly historical coal imports data, as specified in Section 202 of the Energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons.

  19. Quarterly coal report, January--March 1995

    SciTech Connect

    1995-08-24

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended. This report presents detailed quarterly data for January through March 1995 and aggregated quarterly historical data for 1987 through the fourth quarter of 1994. Appendix A displays, from 1987 on, detailed quarterly historical coal imports data, as specified in Section 202 of the Energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons.

  20. Quarterly coal report, January--March 1997

    SciTech Connect

    1997-08-01

    This Quarterly Coal Report (QCR) provides comprehensive information about U.S. coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience,including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended. This report presents detailed quarterly data for January through March 1997 and aggregated quarterly historical data for 1991 through the fourth quarter of 1996. Appendix A displays, from 1988 on, detailed quarterly historical coal imports data, as specified in Section 202 of the Energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons.

  1. Quarterly coal report, October--December 1997

    SciTech Connect

    1998-05-01

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities. This report presents detailed quarterly data for october through December 1997 and aggregated quarterly historical data for 1991 through the third quarter of 1997. Appendix A displays, from 1991 on, detailed quarterly historical coal imports data, as specified in Section 202 of the energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons. To provide a complete picture of coal supply and demand in the US, historical information has been integrated in this report. 8 figs., 73 tabs.

  2. Quarterly coal report, January--March 1994

    SciTech Connect

    Not Available

    1994-08-24

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended. This report presents detailed quarterly data for January through March 1994 and aggregated quarterly historical data for 1986 through the fourth quarter of 1993. Appendix A displays, from 1986 on, detailed quarterly historical coal imports data, as specified in Section 202 of the Energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons.

  3. Presenting practice financial information.

    PubMed

    Webster, Lee Ann H

    2007-01-01

    Medical practice leadership teams, often consisting primarily of physicians with limited financial backgrounds, must make important business decisions and continuously monitor practice operations. In order to competently perform this duty, they need financial reports that are relevant and easy to understand. This article explores financial reporting and decision-making in a physician practice. It discusses reports and tools, such as ratios, graphs, and comparisons, that practices typically include in their reports. Because profitability and cash flow are often the most important financial considerations for physician practices, reports should generally focus on the impact of various activities and potential decisions upon these concerns. This article also provides communication tips for both those presenting practice financial information and those making the decisions. By communicating effectively, these leaders can best use financial information to improve decision-making and maximize financial performance.

  4. Presenting practice financial information.

    PubMed

    Webster, Lee Ann H

    2007-01-01

    Medical practice leadership teams, often consisting primarily of physicians with limited financial backgrounds, must make important business decisions and continuously monitor practice operations. In order to competently perform this duty, they need financial reports that are relevant and easy to understand. This article explores financial reporting and decision-making in a physician practice. It discusses reports and tools, such as ratios, graphs, and comparisons, that practices typically include in their reports. Because profitability and cash flow are often the most important financial considerations for physician practices, reports should generally focus on the impact of various activities and potential decisions upon these concerns. This article also provides communication tips for both those presenting practice financial information and those making the decisions. By communicating effectively, these leaders can best use financial information to improve decision-making and maximize financial performance. PMID:17974087

  5. Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications

    PubMed Central

    Levinson, Douglas F.; Duan, Jubao; Oh, Sang; Wang, Kai; Sanders, Alan R.; Shi, Jianxin; Zhang, Nancy; Mowry, Bryan J.; Olincy, Ann; Amin, Farooq; Cloninger, C. Robert; Silverman, Jeremy M.; Buccola, Nancy G.; Byerley, William F.; Black, Donald W.; Kendler, Kenneth S.; Freedman, Robert; Dudbridge, Frank; Pe’er, Itsik; Hakonarson, Hakon; Bergen, Sarah E.; Fanous, Ayman H.; Holmans, Peter A.; Gejman, Pablo V.

    2015-01-01

    Objective To evaluate previously reported associations of copy number variants (CNVs) with schizophrenia and to identify additional associations, the authors analyzed CNVs in the Molecular Genetics of Schizophrenia study (MGS) and additional available data. Method After quality control, MGS data for 3,945 subjects with schizophrenia or schizoaffective disorder and 3,611 screened comparison subjects were available for analysis of rare CNVs (<1% frequency). CNV detection thresholds were chosen that maximized concordance in 151 duplicate assays. Pointwise and gene-wise analyses were carried out, as well as analyses of previously reported regions. Selected regions were visually inspected and confirmed with quantitative polymerase chain reaction. Results In analyses of MGS data combined with other available data sets, odds ratios of 7.5 or greater were observed for previously reported deletions in chromosomes 1q21.1, 15q13.3, and 22q11.21, duplications in 16p11.2, and exon-disrupting deletions in NRXN1. The most consistently supported candidate associations across data sets included a 1.6-Mb deletion in chromosome 3q29 (21 genes, TFRC to BDH1) that was previously described in a mild-moderate mental retardation syndrome, exonic duplications in the gene for vasoactive intestinal peptide receptor 2 (VIPR2), and exonic duplications in C16orf72. The case subjects had a modestly higher genome-wide number of gene-containing deletions (>100 kb and >1 Mb) but not duplications. Conclusions The data strongly confirm the association of schizophrenia with 1q21.1, 15q13.3, and 22q11.21 deletions, 16p11.2 duplications, and exonic NRXN1 deletions. These CNVs, as well as 3q29 deletions, are also associated with mental retardation, autism spectrum disorders, and epilepsy. Additional candidate genes and regions, including VIPR2, were identified. Study of the mechanisms underlying these associations should shed light on the pathophysiology of schizophrenia. PMID:21285140

  6. Quarterly coal report, April--June 1990

    SciTech Connect

    Not Available

    1990-11-02

    The Quarterly Coal Report provides comprehensive information about US coal production, exports, imports, receipts, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. This issue presents detailed quarterly data for April 1990 through June 1990, aggregated quarterly historical data for 1982 through the second quarter of 1990, and aggregated annual historical data for 1960 through 1989 and projected data for selected years from 1995 through 2010. To provide a complete picture of coal supply and demand in the United States, historical information and forecasts have been integrated in this report. 7 figs., 37 tabs.

  7. Short-term energy outlook, quarterly projections, second quarter 1998

    SciTech Connect

    1998-04-01

    The Energy Information Administration (EIA) prepares quarterly short-term energy supply, demand, and price projections. The details of these projections, as well as monthly updates, are available on the Internet at: www.eia.doe.gov/emeu/steo/pub/contents.html. The paper discusses outlook assumptions; US energy prices; world oil supply and the oil production cutback agreement of March 1998; international oil demand and supply; world oil stocks, capacity, and net trade; US oil demand and supply; US natural gas demand and supply; US coal demand and supply; US electricity demand and supply; US renewable energy demand; and US energy demand and supply sensitivities. 29 figs., 19 tabs.

  8. Applied Meteorology Unit (AMU) Quarterly Report. First Quarter FY-05

    NASA Technical Reports Server (NTRS)

    Bauman, William; Wheeler, Mark; Lambert, Winifred; Case, Jonathan; Short, David

    2005-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the first quarter of Fiscal Year 2005 (October - December 2005). Tasks reviewed include: (1) Objective Lightning Probability Forecast: Phase I, (2) Severe Weather Forecast Decision Aid, (3) Hail Index, (4) Stable Low Cloud Evaluation, (5) Shuttle Ascent Camera Cloud Obstruction Forecast, (6) Range Standardization and Automation (RSA) and Legacy Wind Sensor Evaluation, (7) Advanced Regional Prediction System (ARPS) Optimization and Training Extension, and (8) User Control Interface for ARPS Data Analysis System (ADAS) Data Ingest

  9. Applied Meteorology Unit (AMU) Quarterly Report Third Quarter FY-08

    NASA Technical Reports Server (NTRS)

    Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Dreher, Joseph

    2008-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the third quarter of Fiscal Year 2008 (April - June 2008). Tasks reported on are: Peak Wind Tool for User Launch Commit Criteria (LCC), Anvil Forecast Tool in AWIPS Phase II, Completion of the Edward Air Force Base (EAFB) Statistical Guidance Wind Tool, Volume Averaged Height Integ rated Radar Reflectivity (VAHIRR), Impact of Local Sensors, Radar Scan Strategies for the PAFB WSR-74C Replacement, VAHIRR Cost Benefit Analysis, and WRF Wind Sensitivity Study at Edwards Air Force Base

  10. Applied Meteorology Unit (AMU) Quarterly Report - Fourth Quarter FY-09

    NASA Technical Reports Server (NTRS)

    Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Wheeler, Mark

    2009-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the fourth quarter of Fiscal Year 2009 (July - September 2009). Tasks reports include: (1) Peak Wind Tool for User Launch Commit Criteria (LCC), (2) Objective Lightning Probability Tool. Phase III, (3) Peak Wind Tool for General Forecasting. Phase II, (4) Update and Maintain Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS), (5) Verify MesoNAM Performance (6) develop a Graphical User Interface to update selected parameters for the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLlT)

  11. Short-term energy outlook. Quarterly projections, Third quarter 1994

    SciTech Connect

    Not Available

    1994-08-02

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent cases with those of other forecasting services, and discusses current topics related to the short-term energy markets. (See Short-Term Energy Outlook Annual Supplement, DOE/EIA-0202). The feature article for this issue is Demand, Supply and Price Outlook for Reformulated Gasoline, 1995.

  12. Delineation of an estimated 6.7 MB candidate interval for an anophthalmia gene at 3q26.33-q28 and description of the syndrome associated with visible chromosome deletions of this region.

    PubMed

    Male, Alison; Davies, Angela; Bergbaum, Anne; Keeling, Jean; FitzPatrick, David; Mackie Ogilvie, Caroline; Berg, Jonathan

    2002-12-01

    Anophthalmia or microphthalmia occur in approximately one in 10 children who have severe visual impairment. These eye malformations are often of unknown aetiology, but can be inherited in autosomal dominant, recessive or X-linked forms, and can also occur in association with specific chromosome abnormalities. Four children are described in the medical literature with microphthalmia or anophthalmia in association with chromosome rearrangements involving distal 3q, suggesting the presence of a micro/anophthalmia gene in this region. We have identified two further patients with micro/anophthalmia and chromosome rearrangements involving 3q26-->3q27 and identified a 6.7 MB common deleted region. Patient 1 had multiple abnormalities including bilateral anophthalmia, abnormalities of the first and second cranial nerves and partial absence of the corpus callosum. His karyotype was 46,XY,del(3)(q26.33q28). Patient 2 had right anophthalmia and left extreme microphthalmia. Her karyotype was 46,XX,del(3)(q26.33q28)t(3;7)(q28;q21.1). Both patients had intrauterine growth retardation (IUGR) and strikingly similar dysmorphic facies consisting of bossed forehead, downward-slanting palpebral fissures, grooved bridge of the nose, prominent low-set ears, small down-turned mouth and small mandible. We identified BAC clones mapping to distal 3q from the ENSEMBL and NCBI Entrez databases. These BAC clones were used as fluorescence in situ hybridisation (FISH) probes to identify the minimum deleted region common to both patients. This interval, between clones RPC11-134F2 and RPC11-132N15, was estimated to be 6.7 MB. We conclude that there is an anophthalmia locus within this interval. Candidate genes mapping to this region include Chordin and DVL3, a homologue of the Drosophila Dishevelled gene.

  13. 1. GENERAL VIEW OF SLAVE QUARTERS No. 2 (right). Located ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. GENERAL VIEW OF SLAVE QUARTERS No. 2 (right). Located north of main house. The building at left is Slave Quarters No. 1 (HABS No. VA-1233 C) - Westend, Slave Quarters No. 2, Route 638 vicinity, Trevilians, Louisa County, VA

  14. 1. CARRIAGE HOUSE (left) AND SLAVE QUARTERS, SOUTH FRONT. A ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. CARRIAGE HOUSE (left) AND SLAVE QUARTERS, SOUTH FRONT. A kitchen was included in the quarters. - Charles Fraser House, Carriage House & Slave Quarters, 55 King Street, Charleston, Charleston County, SC

  15. Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22

    SciTech Connect

    Chakravarti, S.; Sundarraj, N.; Cornuet, P.K.

    1995-06-10

    A human corneal fibroblast cDNA library was screened with a bovine lumican cDNA probe to obtain three clones. Sequencing of the longest clone (1.75 kb) yielded an open reading frame of 1014 bp coding for a 338-amino-acid core protein. Amino acid sequencing of a tryptic peptide resulted in a 9-amino-acid match with the derived primary structure, confirming the identity of these clones. Human lumican displays all of the features of small interstitial proteoglycans: N- and C-terminal domains with highly conserved cysteines and a central domain containing nine repeats of slight variations of the leucine motif LXXLXLXXNXL. Like bovine lumican, the human core protein contains four possible N-glycosylation sites in the central domains, all or some of which are substituted with keratan sulfate side chains. At the amino acid level, it is 90% identical with bovine and 72% identical with the chicken core protein. The gene (LUM) was localized to human chromosome 12 by hybridizing a cDNA probe to a Southern blot containing a humanihamster monochromosomal mapping panel DNA. Further sublocalization to 12q21.3-q22 was performed by the fluorescence in situ hybridization technique using a lumican P1 genomic clone. By immunohistochemical staining, we show lumican`s presence, not only in the corneal stroma as shown previously, but also in the dermal area of the skin, indicating a wider distribution of this proteoglycan. 30 refs., 6 figs.

  16. Plasminogen activator inhibitor type 1 gene is located at region q21. 3-q22 of chromosome 7 and genetically linked with cystic fibrosis

    SciTech Connect

    Klinger, K.W.; Winqvist, R.; Riccio, A.; Andreasen, P.A.; Sartorio, R.; Nielsen, L.S.; Stuart, N.; Stanislovitis, P.; Watkins, P.; Douglas, R.

    1987-12-01

    The regional chromosomal location of the human gene for plasminogen activator inhibitor type 1 (PAI1) was determined by three independent methods of gene mapping. PAI1 was localized first to 7cen-q32 and then to 7q21.3-q22 by Southern blot hybridization analysis of a panel of human and mouse somatic cell hybrids with a PAI1 cDNA probe and in situ hybridization, respectively. The authors frequent HindIII restriction fragment length polymorphism (RFLP) of the PAI1 gene with an information content of 0.369. In family studies using this polymorphism, genetic linkage was found between PAI1 and the loci for erythropoietin (EPO), paraoxonase (PON), the met protooncogene (MET), and cystic fibrosis (CF), all previously assigned to the middle part of the long arm of chromosome 7. The linkage with EPO was closest with an estimated genetic distance of 3 centimorgans, whereas that to CF was 20 centimorgans. A three-point genetic linkage analysis and data from previous studies showed that the most likely order of these loci is EPO, PAI1, PON, (MET, CF), with PAI1 being located centromeric to CF. The PAI1 RFLP may prove to be valuable in ordering genetic markers in the CF-linkage group and may also be valuable in genetic analysis of plasminogen activation-related diseases, such as certain thromboembolic disorders and cancer.

  17. Ab-initio study of structural and electronic properties of thin film and bulk forms of Bi2Q3 (Q = Se, Te) as topological insulators

    NASA Astrophysics Data System (ADS)

    Ranjbardizaj, Ahmad; Mizuseki, Hiroshi; Kawazoe, Yoshiyuki

    2013-03-01

    Bi2Q3 (Q =Se, Te) are the best-known bulk thermoelectric materials, which have been demonstrated to be topological insulators (TI). TI's are insulators with conductive surface states consisting of a single Dirac cones. These materials have layered structures consisting of stacked quintuple layers (QL), with relatively weak coupling between the QL's. Therefore, it might be easy to prepare the Bi2Q3 in the form of thin films with particular thicknesses using the available experimental techniques. In this study, the electronic and structural properties of bulk Bi2Se3 are investigated using density functional theory. Our results show that the Bi2Se3 is an indirect semiconductor with energy gap of ~ 0.27 eV. Additionally, the electronic structure dependence of Bi2Se3to the thicknesses of thin films (n-QL's with n =1,2...9) is considered. It is observed that the electronic structure of this kind of thin films depends on the number of QL's. For n-QL's with n larger than three, the thin film has a bulk band gap and has protected conducting states on its surface. Moreover, the effect of number of layers (n) on band-gap energy is studied. Similar calculations and discussions are carried out for Bi2Te3 and the results are compared to the Bi2Se3 case and also the available theoretical and experimental results.

  18. Fine mapping of the autosomal dominant split hand/split foot locus on chromosome 7, band q21. 3-q. 22. 1

    SciTech Connect

    Scherer, S.W.; Tsui, L.C. ); Allen, T.; Kim, J.; Soder, S. ); Poorkaj, P.; Geshuri, D.; Nunes, M.; Stephens, K.; Pagon, R.A. )

    1994-07-01

    Split hand/split foot (SHFD) is a human developmental defect characterized by missing digits, fusion of remaining digits, and a deep median cleft in the hands and feet. Cytogenetic studies of deletions and translocations associated with this disorder have indicated that an autosomal dominant split hand/split foot locus (gene SHFD1) maps to 7q21-q22. To characterize the SHFD1 locus, somatic cell hybrid lines were constructed from cytogenetically abnormal individuals with SHFD. Molecular analysis resulted in the localization of 93 DNA markers to one of 10 intervals surrounding the SHFD1 locus. The translocation breakpoints in four SHFD patients were encompassed by the smallest region of overlap among the SHFD-associated deletions. The order of DNA markers in the SHFD1 critical region has been defined as PON-D7S812-SHFD1-D7S811-ASNS. One DNA marker, D7S811, detected altered restriction enzyme fragments in three patients with translocations when examined by pulsed-field gel electrophoresis (PFGE). These data map SHFD1, a gene that is crucial for human limb differentiation, to a small interval in the q21.3-q.22.1 region of human chromosome 7. 54 refs., 4 figs., 2 tabs.

  19. Mixed gonadal dysgenesis in a patient with de novo tas(Y;19)(p11.3;q13.4) and 45,X mosaicism.

    PubMed

    Cetin, Zafer; Parlak, Mesut; Altiok Clark, Ozden; Karaguzel, Gungor; Luleci, Guven; Bircan, Iffet; Berker-Karauzum, Sibel

    2013-09-01

    We report a patient with a de novo telomeric association between chromosomes 19 and Y in conjunction with mixed gonadal dysgenesis. The patient was first admitted to the clinic because of abnormal external genitalia. Laparoscopic evaluation revealed (1) a rudimentary uterus, one fallopian tube, and a small gonad resembling an ovary on the right side, and (2) an immature fallopian tube, a vas deferens, and a gonad resembling a testis on the left side. Conventional cytogenetic analysis performed on cultivated peripheral blood cells, and tissue obtained from the phallus and a gonadal structure which resembled a testis revealed two different cell lines with the 46,X,tas (Y;19)(p11.3;q13.4) and 45,X karyotype. Y chromosome microdeletion analysis showed that the patient did not have any genomic deletions in the AZFa, b, c, or SRY regions on the long arm of the Y chromosome. This is the first report of a patient with mixed gonadal dysgenesis that is accompanied by a telomeric association between chromosomes 19 and Y with 45,X mosaicism. PMID:23652939

  20. A novel locus for alopecia with mental retardation syndrome (APMR2) maps to chromosome 3q26.2-q26.31.

    PubMed

    Wali, A; John, P; Gul, A; Lee, K; Chishti, M S; Ali, G; Hassan, M J; Leal, S M; Ahmad, W

    2006-09-01

    Congenital alopecia may occur either alone or in association with ectodermal and other abnormalities. On the bases of such associations, several different syndromes featuring congenital alopecia can be distinguished. Alopecia with mental retardation syndrome (APMR) is a rare autosomal recessive disorder, clinically characterized by total or partial hair loss and mental retardation. In the present study, a five-generation Pakistani family with multiple affected individuals with APMR was ascertained. Patients in this family exhibited typical features of APMR syndrome. The disease locus was mapped to chromosome 3q26.2-q26.31 by carrying out a genome scan followed by fine mapping. A maximum two-point logarithm of odds (LOD) score of 2.93 at theta=0.0 was obtained at markers D3S3053 and D3S2309. Multipoint linkage analysis resulted in a maximum LOD score of 4.57 with several markers, which supports the linkage. The disease locus was flanked by markers D3S1564 and D3S2427, which corresponds to 9.6-cM region according to the Rutgers combined linkage-physical map of the human genome (build 35) and contains 5.6 Mb. The linkage interval of the APMR locus identified here does not overlap with the one described previously; therefore, this locus has been designated as APMR2.

  1. Genome-wide significant association between a ‘negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1

    PubMed Central

    Meier, S; Mattheisen, M; Vassos, E; Strohmaier, J; Treutlein, J; Josef, F; Breuer, R; Degenhardt, F; Mühleisen, T W; Müller-Myhsok, B; Steffens, M; Schmael, C; McMahon, F J; Kelsoe, John R; Greenwood, Tiffany A; Nievergelt, Caroline M; Barrett, Thomas B; McKinney, Rebecca; Shilling, Paul D; Schork, Nicholas J; Smith, Erin N; Bloss, Cinnamon S; Nurnberger, John; Edenberg, Howard J; Foroud, Tatiana; Koller, Daniel L; Gershon, Elliot S; Liu, Chun-Yu; Badner, Judith A; Scheftner, William; Lawson, William B; Nwulia, Evaristus A; Hipolito, Maria; Coryell, William; Rice, John; Byerley, William; McMahon, Francis; Chen, David TW; Schulze, Thomas G; Berrettini, Wade; Potash, James B; Zandi, Peter P; Mahon, Pamela B; McInnis, Melvin; Craig, David; Szelinger, Szabolcs; Nöthen, M M; Cichon, S; Schulze, T G; Rietschel, M

    2012-01-01

    Research suggests that clinical symptom dimensions may be more useful in delineating the genetics of bipolar disorder (BD) than standard diagnostic models. To date, no study has applied this concept to data from genome-wide association studies (GWAS). We performed a GWAS of factor dimensions in 927 clinically well-characterized BD patients of German ancestry. Rs9875793, which is located in an intergenic region of 3q26.1 and in the vicinity of the solute carrier family 2 (facilitated glucose transporter), member 2 gene (SLC2A2), was significantly associated with the factor analysis-derived dimension ‘negative mood delusions' (n=927; P=4.65 × 10−8, odds ratio (OR)=2.66). This dimension was comprised of the symptoms delusions of poverty, delusions of guilt and nihilistic delusions. In case–control analyses, significant association with the G allele of rs9875793 was only observed in the subgroup of BD patients who displayed symptoms of ‘negative mood delusions' (allelic χ2 model: PG=0.0001, OR=1.92; item present, n=89). Further support for the hypothesis that rs9875793 is associated with BD in patients displaying ‘negative mood delusions' symptom, such as delusions of guilt, was obtained from an European American sample (GAIN/TGEN), which included 1247 BD patients and 1434 controls (PEA=0.028, OR=1.27). PMID:23010768

  2. Mapping of the human BAX gene to chromosome 19q13.3-q13.4 and isolation of a novel alternatively spliced transcript, BAX{delta}

    SciTech Connect

    Apte, S.S.; Olsen, B.R.; Mattei, M.G.

    1995-04-10

    The BAX gene is a member of the Bcl-2 gene family; it encodes a 21-kDa protein whose association with Bcl-2 is believed to play a critical role in regulating apoptosis. Through analysis of human-hamster somatic cell hybrid DNA and by in situ hybridization to metaphase chromosomes, we have determined that the human BAX gene is located in the q13.3-q13.4 region of human chromosome 19. We have also isolated a BAX cDNA clone in which that part of the mRNA encoded by exon 3 is absent. The skipping of exon 3 and the resultant splicing of exons 2 and 4 maintains the original reading frame and predicts the existence of an interstitially truncated form of the major Bax protein (Bax{alpha}), termed Bax{delta}. Unlike two previously described variant forms of Bax{alpha} (Bax{beta} and Bax{tau}), Bax{delta} retains the functionally critical C-terminal membrane anchor region as well as the Bcl-2 homology 1 and 2 (BH1 and BH2) domains. 10 refs., 1 fig., 1 tab.

  3. 9q33.3q34.11 microdeletion: new contiguous gene syndrome encompassing STXBP1, LMX1B and ENG genes assessed using reverse phenotyping.

    PubMed

    Nambot, Sophie; Masurel, Alice; El Chehadeh, Salima; Mosca-Boidron, Anne-Laure; Thauvin-Robinet, Christel; Lefebvre, Mathilde; Marle, Nathalie; Thevenon, Julien; Perez-Martin, Stéphanie; Dulieu, Véronique; Huet, Frédéric; Plessis, Ghislaine; Andrieux, Joris; Jouk, Pierre-Simon; Billy-Lopez, Gipsy; Coutton, Charles; Morice-Picard, Fanny; Delrue, Marie-Ange; Heron, Delphine; Rooryck, Caroline; Goldenberg, Alice; Saugier-Veber, Pascale; Joly-Hélas, Géraldine; Calenda, Patricia; Kuentz, Paul; Manouvrier-Hanu, Sylvie; Dupuis-Girod, Sophie; Callier, Patrick; Faivre, Laurence

    2016-06-01

    The increasing use of array-CGH in malformation syndromes with intellectual disability could lead to the description of new contiguous gene syndrome by the analysis of the gene content of the microdeletion and reverse phenotyping. Thanks to a national and international call for collaboration by Achropuce and Decipher, we recruited four patients carrying de novo overlapping deletions of chromosome 9q33.3q34.11, including the STXBP1, the LMX1B and the ENG genes. We restrained the selection to these three genes because the effects of their haploinsufficency are well described in the literature and easily recognizable clinically. All deletions were detected by array-CGH and confirmed by FISH. The patients display common clinical features, including intellectual disability with epilepsy, owing to the presence of STXBP1 within the deletion, nail dysplasia and bone malformations, in particular patellar abnormalities attributed to LMX1B deletion, epistaxis and cutaneous-mucous telangiectasias explained by ENG haploinsufficiency and common facial dysmorphism. This systematic analysis of the genes comprised in the deletion allowed us to identify genes whose haploinsufficiency is expected to lead to disease manifestations and complications that require personalized follow-up, in particular for renal, eye, ear, vascular and neurological manifestations. PMID:26395556

  4. Pericentric inversion of chromosome 11 (p14.3q21) associated with developmental delays, hypopigmented skin lesions and abnormal brain MRI findings - a new case report

    SciTech Connect

    Zachor, D.A.; Lofton, M.

    1994-09-01

    We report 3 year old male, referred for evaluation of developmental delays. Pregnancy was complicated by oligohydramnios, proteinuria and prematurity. Medical history revealed: bilateral inguinal hernia, small scrotal sac, undescended testes, developmental delays and behavioral problems. The child had: microcephaly, facial dysmorphic features, single palmar creases, hypopigmented skin lesions of variable size, intermittent exotropia and small retracted testes. Neurological examination was normal. Cognitive level was at the average range with mild delay in his adaptive behavior. Expressive language delays and severe articulation disorder were noted, as well as clumsiness, poor control and precision of gross and fine motor skills. Chromosomal analysis of peripheral leukocytes indicated that one of the number 11 chromosomes had undergone a pericentric inversion with breakpoints on the short (p) arm at band p14.3 and the long (q) arm at band q21. An MRI of the brain showed mild delay in myelinization pattern of white matter. Chromosome 11 inversion in other sites was associated with Beckwith-Wiedemann syndrome and several malignancies. To our knowledge this is the first description of inv(11)(p14.3q21) that is associated with microcephaly, dysmorphic features, hypopigmented skin lesions and speech delay. This inversion may disrupt the expression of the involved genes. However, additional cases with the same cytogenetic anomaly are needed to explore the phenotypic significance of this disorder.

  5. Quarterly coal report, January--March 1993

    SciTech Connect

    Not Available

    1993-08-20

    The United States produced 242 million short tons of coal in the first quarter of 1993, a decrease of 6 percent (14 million short tons) from the amount produced during the first quarter of 1992. The decrease was due to a decline in production east of the Mississippi River. All major coal-producing States in this region had lower coal production levels led by West Virginia, which produced 5 million short tons less coal. The principal reasons for the overall drop in coal output compared to a year earlier were: A decrease in demand for US coal in foreign markets; a slower rate of producer/distributor stock build-up; and a drawn-down of electric utility coal stocks. Distribution of US coal in the first quarter of 1993 was 10 million short tons lower than in the first quarter of 1992, with 5 million short tons less distributed to both electric utilities and overseas markets. The average price of coal delivered to electric utilities during the first quarter of 1993 was $28.65 per short ton, the lowest value since the first quarter of 1980. Coal consumption in the first quarter of 1993 was 230 million short tons, 4 percent higher than in the first quarter of 1992, due primarily to a 5-percent increase in consumption at electric utility plants. Total consumer stocks, at 153 million short tons, and electric utility stocks, at 144 million short tons, were at their lowest quarterly level since the end of 1989. US. coal exports totaled 19 million short tons, 6 million short tons less than in the first quarter of 1992, and the lowest quarterly level since 1988. The decline was primarily due to a 1-million-short-ton drop in exports to each of the following destinations: Italy, France, Belgium and Luxembourg, and Canada.

  6. Weldon Spring Site Remedial Action Project quarterly environmental data summary (QEDS) for fourth quarter 1998

    SciTech Connect

    1999-02-01

    This report contains the Quarterly Environmental Data Summary (QEDS) for the fourth quarter of 1998 in support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement. The data, except for air monitoring data and site KPA generated data (uranium analyses) were received from the contract laboratories, verified by the Weldon Spring Site verification group, and merged into the database during the fourth quarter of 1998. KPA results for on-site total uranium analyses performed during fourth quarter 1998 are included. Air monitoring data presented are the most recent complete sets of quarterly data.

  7. 14. INTERIOR OF TYPICAL SLEEPING QUARTERS, BUILDING 208, LOOKING SOUTHEAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR OF TYPICAL SLEEPING QUARTERS, BUILDING 208, LOOKING SOUTHEAST. - Mill Valley Air Force Station, Bachelor Airmen Quarters, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  8. 46 CFR 131.570 - Quarterly inspections.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Quarterly inspections. 131.570 Section 131.570 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Tests, Drills, and Inspections § 131.570 Quarterly inspections. (a) Each apparatus that controls a lifeboat winch, including motor controllers,...

  9. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.29 Quarterly inventory. (a) Each licensee shall conduct a...

  10. 10 CFR 34.29 - Quarterly inventory.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Quarterly inventory. 34.29 Section 34.29 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Equipment § 34.29 Quarterly inventory. (a) Each licensee shall conduct a...

  11. RTO Technical Publications: A Quarterly Listing

    NASA Technical Reports Server (NTRS)

    2005-01-01

    A quarterly listing of RTO technical publications is presented. The topics include: Handbook on the Analysis of Smaller-Scale Contingency Operations in Long Term Defence Planning; 2) Radar Polarimetry and Interferometry; 3) Combat Casualty Care in Ground-Based Tactical Situations: Trauma Technology and Emergency Medical Procedures; and 4) RTO Technical Publications: A Quarterly Listing

  12. 49 CFR 573.7 - Quarterly reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Quarterly reports. 573.7 Section 573.7... § 573.7 Quarterly reports. (a) Each manufacturer who is conducting a defect or noncompliance... accordance with the manufacturer's plan provided to NHTSA pursuant to § 573.6(c)(9); (ii) The...

  13. 49 CFR 573.7 - Quarterly reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Quarterly reports. 573.7 Section 573.7... § 573.7 Quarterly reports. (a) Each manufacturer who is conducting a defect or noncompliance... accordance with the manufacturer's plan provided to NHTSA pursuant to § 573.6(c)(9); (ii) The...

  14. Idaho National Laboratory Quarterly Occurrence Analysis

    SciTech Connect

    Mitchell, Lisbeth Ann

    2015-11-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 85 reportable events (18 from the 4th Qtr FY-15 and 67 from the prior three reporting quarters), as well as 25 other issue reports (including events found to be not reportable and Significant Category A and B conditions) identified at INL during the past 12 months (8 from this quarter and 17 from the prior three quarters).

  15. Clinical, Cytogenetic, and Biochemical Analyses of a Family with a t(3;13)(q26.2;p11.2): Further Delineation of 3q Duplication Syndrome

    PubMed Central

    Abreu-González, M.; García-Delgado, C.; Cervantes, A.; Aparicio-Onofre, A.; Guevara-Yáñez, R.; Sánchez-Urbina, R.; Gallegos-Arreola, M. P.; Luna-Angulo, A.; Estrada, F. J.; Morán-Barroso, V. F.

    2013-01-01

    Chromosomal abnormalities that result in genomic imbalances are a major cause of congenital and developmental anomalies. Partial duplication of chromosome 3q syndrome is a well-described condition, and the phenotypic manifestations include a characteristic facies, microcephaly, hirsutism, synophrys, broad nasal bridge, congenital heart disease, genitourinary disorders, and mental retardation. Approximately 60%–75% of cases are derived from a balanced translocation. We describe a family with a pure typical partial trisomy 3q syndrome derived from a maternal balanced translocation t(3;13)(q26.2;p11.2). As the chromosomal rearrangement involves the short arm of an acrocentric chromosome, the phenotype corresponds to a pure trisomy 3q26.2-qter syndrome. There are 4 affected individuals and several carriers among three generations. The report of this family is relevant because there are few cases of pure duplication 3q syndrome reported, and the cases described here contribute to define the phenotype associated with the syndrome. Furthermore, we confirmed that the survival until adulthood is possible. This report also identified the presence of glycosaminoglycans in urine in this family, not related to the chromosomal abnormality or the phenotype. PMID:24151567

  16. Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: A role in ovarian pathogenesis

    SciTech Connect

    Nanjundan, Meera; Cheng, Kwai Wa; Zhang, Fan; Lahad, John; Kuo, Wen-Lin; Schmandt, Rosemarie; Smith-McCune, Karen; Fishman, David; Gray, Joe W.; Mills, Gordon B.

    2008-07-18

    High-resolution array comparative genomic hybridization of 235 serous epithelial ovarian cancers demonstrated a regional increase at 3q26.2 encompassing SnoN/SkiL, a coregulator of SMAD/TGF{beta} signaling. SnoN RNA transcripts were elevated in {approx}80% of advanced stage serous epithelial ovarian cancers. In both immortalized normal (TIOSE) and ovarian carcinoma cell lines (OVCA), SnoN RNA levels were increased by TGF{beta} stimulation and altered by LY294002 and JNK II inhibitor treatment suggesting that the PI3K and JNK signaling pathways may regulate TGF{beta}-induced increases in SnoN RNA. In TIOSE, SnoN protein levels were reduced 15min post TGF{beta}-stimulation, likely by proteosome-mediated degradation. In contrast, in OVCA, SnoN levels were elevated 3h post-stimulation potentially as a result of inhibition of the proteosome. To elucidate the role of SnoN in ovarian tumorigenesis, we explored the effects of both increasing and decreasing SnoN levels. In both TIOSE and OVCA, SnoN siRNA decreased cell growth between 20 and 50% concurrent with increased p21 levels. In TIOSE, transient expression of SnoN repressed TGF{beta} induction of PAI-1 promoters with little effect on the p21 promoter or resultant cell growth. In contrast to the effects of transient expression, stable expression of SnoN in TIOSE led to growth arrest through induction of senescence. Collectively, these results implicate SnoN levels in multiple roles during ovarian carcinogenesis: promoting cellular proliferation in ovarian cancer cells and as a positive mediator of cell cycle arrest and senescence in non-transformed ovarian epithelial cells.

  17. A genome wide association study of mathematical ability reveals an association at chromosome 3q29, a locus associated with autism and learning difficulties: a preliminary study.

    PubMed

    Baron-Cohen, Simon; Murphy, Laura; Chakrabarti, Bhismadev; Craig, Ian; Mallya, Uma; Lakatošová, Silvia; Rehnstrom, Karola; Peltonen, Leena; Wheelwright, Sally; Allison, Carrie; Fisher, Simon E; Warrier, Varun

    2014-01-01

    Mathematical ability is heritable, but few studies have directly investigated its molecular genetic basis. Here we aimed to identify specific genetic contributions to variation in mathematical ability. We carried out a genome wide association scan using pooled DNA in two groups of U.K. samples, based on end of secondary/high school national academic exam achievement: high (n = 419) versus low (n = 183) mathematical ability while controlling for their verbal ability. Significant differences in allele frequencies between these groups were searched for in 906,600 SNPs using the Affymetrix GeneChip Human Mapping version 6.0 array. After meeting a threshold of p<1.5×10(-5), 12 SNPs from the pooled association analysis were individually genotyped in 542 of the participants and analyzed to validate the initial associations (lowest p-value 1.14 ×10(-6)). In this analysis, one of the SNPs (rs789859) showed significant association after Bonferroni correction, and four (rs10873824, rs4144887, rs12130910 rs2809115) were nominally significant (lowest p-value 3.278 × 10(-4)). Three of the SNPs of interest are located within, or near to, known genes (FAM43A, SFT2D1, C14orf64). The SNP that showed the strongest association, rs789859, is located in a region on chromosome 3q29 that has been previously linked to learning difficulties and autism. rs789859 lies 1.3 kbp downstream of LSG1, and 700 bp upstream of FAM43A, mapping within the potential promoter/regulatory region of the latter. To our knowledge, this is only the second study to investigate the association of genetic variants with mathematical ability, and it highlights a number of interesting markers for future study.

  18. Isolation of cosmid and cDNA clones in the region surrounding the BTK gene at Xq21.3-q22

    SciTech Connect

    Vorechovsky, I.; Zhou, J.N.; Hammarstroem, L.

    1994-06-01

    A regional physical and transcription map involving yeast artificial chromosomes (YACs), cosmids, and cDNAs has been constructed for Xq21.3-q22 around the gene BTK (formerly atk or BPK) defective in X-linked agammaglobulinemia (XLA). With a positional cloning strategy employing direct cDNA selection, novel cDNAs were found to cluster in the region of approximately 100 kb flanking the XLA and {alpha}-galactosidase A loci. While these widely expressed transcripts are in the area known to contain CpG islands, a less evolutionarily conserved gene, located more than 130 kb distal of DXS178, maps to cosmid clones that could not be digested with rare-cutting restriction enzymes. The presence of transcribed sequences flanking the BTK allowed investigation of their involvement in complex XLA phenotypes. Southern blot analysis using cDNA clones isolated from this region permitted exclusion of a contiguous deletion syndrome as an underlying defect in three patients with XLA and associated growth hormone deficiency. A single XLA patient with torsion dystonia and cosegregating X-linked deafness has been found with a deletion in the 3{prime} part of BTK extending centromerically into the flanking expressed sequence DXS1274E. This suggests a possible involvement of the DXS1274E in this phenotype. The GenBank accession numbers for novel cDNA sequences are as follows: DXS1269E (L20773), DXS1271E (UO1923), DXS1273E (UO1925), and DXS1274E (UO1922). 51 refs., 4 figs., 1 tab.

  19. Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.

    PubMed

    Childs, Erica J; Mocci, Evelina; Campa, Daniele; Bracci, Paige M; Gallinger, Steven; Goggins, Michael; Li, Donghui; Neale, Rachel E; Olson, Sara H; Scelo, Ghislaine; Amundadottir, Laufey T; Bamlet, William R; Bijlsma, Maarten F; Blackford, Amanda; Borges, Michael; Brennan, Paul; Brenner, Hermann; Bueno-de-Mesquita, H Bas; Canzian, Federico; Capurso, Gabriele; Cavestro, Giulia M; Chaffee, Kari G; Chanock, Stephen J; Cleary, Sean P; Cotterchio, Michelle; Foretova, Lenka; Fuchs, Charles; Funel, Niccola; Gazouli, Maria; Hassan, Manal; Herman, Joseph M; Holcatova, Ivana; Holly, Elizabeth A; Hoover, Robert N; Hung, Rayjean J; Janout, Vladimir; Key, Timothy J; Kupcinskas, Juozas; Kurtz, Robert C; Landi, Stefano; Lu, Lingeng; Malecka-Panas, Ewa; Mambrini, Andrea; Mohelnikova-Duchonova, Beatrice; Neoptolemos, John P; Oberg, Ann L; Orlow, Irene; Pasquali, Claudio; Pezzilli, Raffaele; Rizzato, Cosmeri; Saldia, Amethyst; Scarpa, Aldo; Stolzenberg-Solomon, Rachael Z; Strobel, Oliver; Tavano, Francesca; Vashist, Yogesh K; Vodicka, Pavel; Wolpin, Brian M; Yu, Herbert; Petersen, Gloria M; Risch, Harvey A; Klein, Alison P

    2015-08-01

    Pancreatic cancer is the fourth leading cause of cancer death in the developed world. Both inherited high-penetrance mutations in BRCA2 (ref. 2), ATM, PALB2 (ref. 4), BRCA1 (ref. 5), STK11 (ref. 6), CDKN2A and mismatch-repair genes and low-penetrance loci are associated with increased risk. To identify new risk loci, we performed a genome-wide association study on 9,925 pancreatic cancer cases and 11,569 controls, including 4,164 newly genotyped cases and 3,792 controls in 9 studies from North America, Central Europe and Australia. We identified three newly associated regions: 17q25.1 (LINC00673, rs11655237, odds ratio (OR) = 1.26, 95% confidence interval (CI) = 1.19-1.34, P = 1.42 × 10(-14)), 7p13 (SUGCT, rs17688601, OR = 0.88, 95% CI = 0.84-0.92, P = 1.41 × 10(-8)) and 3q29 (TP63, rs9854771, OR = 0.89, 95% CI = 0.85-0.93, P = 2.35 × 10(-8)). We detected significant association at 2p13.3 (ETAA1, rs1486134, OR = 1.14, 95% CI = 1.09-1.19, P = 3.36 × 10(-9)), a region with previous suggestive evidence in Han Chinese. We replicated previously reported associations at 9q34.2 (ABO), 13q22.1 (KLF5), 5p15.33 (TERT and CLPTM1), 13q12.2 (PDX1), 1q32.1 (NR5A2), 7q32.3 (LINC-PINT), 16q23.1 (BCAR1) and 22q12.1 (ZNRF3). Our study identifies new loci associated with pancreatic cancer risk. PMID:26098869

  20. Applied Meteorology Unit (AMU) Quarterly Report - Fourth Quarter FY-10

    NASA Technical Reports Server (NTRS)

    Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Wheeler, Mark

    2010-01-01

    Three AMU tasks were completed in this Quarter, each resulting in a forecast tool now being used in operations and a final report documenting how the work was done. AMU personnel completed the following tasks (1) Phase II of the Peak Wind Tool for General Forecasting task by delivering an improved wind forecasting tool to operations and providing training on its use; (2) a graphical user interface (GUI) she updated with new scripts to complete the ADAS Update and Maintainability task, and delivered the scripts to the Spaceflight Meteorology Group on Johnson Space Center, Texas and National Weather Service in Melbourne, Fla.; and (3) the Verify MesoNAM Performance task after we created and delivered a GUI that forecasters will use to determine the performance of the operational MesoNAM weather model forecast.

  1. Financial Services Marketing.

    ERIC Educational Resources Information Center

    Olson, Lucretia Maria

    This manual contains student assignments in the financial services area of the marketing process. The individualized competency-based materials are intended to enhance and supplement instruction or to provide the basis for a course of instruction by the teacher-coordinator. Information on skills needed in jobs in financial marketing is first…

  2. Molecular cytogenetic analyses of HIG, a novel human cell line carrying t(1;3)(p36.3;q25.3) established from a patient with chronic myelogenous leukemia in blastic crisis.

    PubMed

    Hosoya, Noriko; Ogawa, Seishi; Motokura, Tohru; Hangaishi, Akira; Wang, Lili; Qiao, Ying; Nannya, Yasuhito; Kogi, Mieko; Hirai, Hisamaru

    2003-12-01

    Chromosomal abnormalities involving 1p36, 3q21, and/or 3q26 have been reported in a subset of myeloid neoplasms having characteristic dysmegakaryopoiesis, and the overexpression of EVI1 on 3q26 or of MEL1 on 1p36 has been implicated in their pathogenesis. We describe molecular cytogenetic analyses of a novel human cell line, HIG, established from a unique case in which a novel translocation t(1;3)(p36;q26) appeared as the sole additional chromosomal abnormality at the time of blastic transformation of chronic myelogenous leukemia. The patient displayed clinical features resembling those of the 3q21q26 syndrome. The HIG cell line retained der(1)t(1;3)(p36;q26) but lost t(9;22)(q34;q11). To identify the relevant gene that would be deregulated by this translocation, we molecularly cloned the translocation's breakpoints. They were distant from the breakpoint cluster regions of the 3q21q26 syndrome or t(1;3)(p36;q21), and neither the EVI1 nor the MEL1 transcript was detected in the HIG cell line. None of the genes located within 150 kilobase pairs of the breakpoints were aberrantly expressed, suggesting that in this case other gene(s) more distant from the breakpoints are deregulated by possible remote effects. Further analyses of the deregulated genes in the HIG cell line should provide important insight into the mechanisms involved in these types of leukemias.

  3. Hawaiian Volcano Observatory 1969 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  4. Hawaiian Volcano Observatory 1966 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  5. Hawaiian Volcano Observatory 1963 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  6. Hawaiian Volcano Observatory 1970 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  7. Hawaiian Volcano Observatory 1971 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  8. Hawaiian Volcano Observatory 1957 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  9. Hawaiian Volcano Observatory 1965 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  10. Hawaiian Volcano Observatory 1959 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  11. Hawaiian Volcano Observatory 1972 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  12. Hawaiian Volcano Observatory 1967 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  13. Hawaiian Volcano Observatory 1973 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  14. Hawaiian Volcano Observatory 1958 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  15. Hawaiian Volcano Observatory 1961 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  16. Hawaiian Volcano Observatory 1960 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  17. Hawaiian Volcano Observatory 1968 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  18. Hawaiian Volcano Observatory 1964 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  19. Hawaiian Volcano Observatory 1962 Quarterly Administrative Report

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    INTRODUCTORY NOTE The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. The earthquake summary data are presented as a listing of origin time, depth, magnitude, and other location parameters. Network instrumentation, field station sites, and location algorithms are described. Tilt and other deformation data are included until Summary 77, January to December 1977. From 1978, the seismic and deformation data are published separately, due to differing schedules of data reduction. There are eight quarters - from the fourth quarter of 1959 to the third quarter of 1961 - that were never published. Two of these (4th quarter 1959, 1st quarter 1960) have now been published, using handwritten notes of Jerry Eaton (HVO seismologist at the time) and his colleagues. The seismic records for the remaining six summaries went back to California in 1961 with Jerry Eaton. Other responsibilities intervened, and the seismic summaries were never prepared.

  20. Be Vigilant on Financial Statements.

    ERIC Educational Resources Information Center

    Freed, DeBow

    2002-01-01

    Highlights areas on university's financial statements that warrant careful review by trustees and suggests ways they can check to see whether an institution's financial statements are clear and valid indicators of its financial status. (EV)

  1. 2. View to northeast showing quarters and outbuildings, L to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. View to northeast showing quarters and outbuildings, L to R: Service Building (HABS No. VA-1287-D), Medical Officer's Quarters C (in background), Garage (HABS No. VA-1287-F), and Medical Officer's Quarters B - Portsmouth Naval Hospital, Medical Officer's Quarters C, West side Williamson Drive, 400 feet South of Rixey Drive, Portsmouth, Portsmouth, VA

  2. 18 CFR 35.10b - Electric Quarterly Reports.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Electric Quarterly... Application § 35.10b Electric Quarterly Reports. Each public utility shall file an updated Electric Quarterly..., file by January 31. Electric Quarterly Reports must be prepared in conformance with the...

  3. 18 CFR 35.10b - Electric Quarterly Reports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Electric Quarterly... Application § 35.10b Electric Quarterly Reports. Each public utility shall file an updated Electric Quarterly..., file by January 31. Electric Quarterly Reports must be prepared in conformance with the...

  4. Quarter-wave pulse tube

    NASA Astrophysics Data System (ADS)

    Swift, G. W.; Gardner, D. L.; Backhaus, S. N.

    2011-10-01

    In high-power pulse-tube refrigerators, the pulse tube itself can be very long without too much dissipation of acoustic power on its walls. The pressure amplitude, the volume-flow-rate amplitude, and the time phase between them evolve significantly along a pulse tube that is about a quarter-wavelength long. Proper choice of length and area makes the oscillations at the ambient end of the long pulse tube optimal for driving a second, smaller pulse-tube refrigerator, thereby utilizing the acoustic power that would typically have been dissipated in the first pulse-tube refrigerator's orifice. Experiments show that little heat is carried from the ambient heat exchanger to the cold heat exchanger in such a long pulse tube, even though the oscillations are turbulent and even when the tube is compactly coiled.

  5. Writing: the Quarterly as text.

    PubMed

    Locke, Lawrence F

    2005-06-01

    The purpose of this essay is to examine how writing has shaped the nature of the Quarterly over 75 years. Here I explore how stylistic elements have changed over time, how form has interacted with function and content, and how well the resulting text has served the several communities within physical education. I make the following assertions. First, the writing style that has become the model for research reports is needlessly dense and daunting for readers. Second, the desire to maintain a journal that serves both as an interdisciplinary resource for a broad audience of physical educators and as an outlet for reports directed to limited audiences of technical specialists has prevented full performance of either function. Those concerns notwithstanding, I find good cause for celebration--as well as for guarded optimism about the future.

  6. Strategic Petroleum Reserve: Annual/quarterly report

    SciTech Connect

    Not Available

    1994-02-16

    Section 165 of the Energy Policy and Conservation Act (Public Law 94-163), as amended, requires the Secretary of Energy to submit annual and quarterly reports to the President and the Congress on activities of the Strategic Petroleum Reserve. This report combines the fourth quarter 1993 Quarterly Report with the 1993 Annual Report. Key activities described include appropriations; life extension planning; expansion planning; Strategic Petroleum Reserve oil acquisition; the oil stabilization program; and the refined petroleum product reserve test programs. Sections of this report also describe the program mission; the storage facility development program; environmental compliance; budget and finance; and drawdown and distribution.

  7. Detection of the NS3 Q80K polymorphism by Sanger and deep sequencing in hepatitis C virus genotype 1a strains in the UK.

    PubMed

    Beloukas, A; King, S; Childs, K; Papadimitropoulos, A; Hopkins, M; Atkins, M; Agarwal, K; Nelson, M; Geretti, A M

    2015-11-01

    The Q80K polymorphism in the hepatitis C virus (HCV) NS3 enzyme reduces susceptibility to simeprevir and other novel protease inhibitors. The aims of this study were to determine the prevalence of Q80K in treatment-naïve HCV-1a carriers in the North West region (NW) and South East region (SE) of England, investigate the occurrence of Q80K as a minority variant, and characterize viral phylogeny. Plasma samples from subjects who were naïve to anti-HCV therapy were subjected to conventional (Sanger) and deep (Illumina-Miseq, 1% interpretative cut-off) sequencing of NS3. Q80K occurred in 44 of 238 subjects (18.5%, 95% CI 13.6-23.4%), including 19 of 70 (27.1%) in the NW and 25 of 168 (14.9%) in the SE (p 0.0425), with no difference in HCV RNA load or human immunodeficiency virus (HIV) status. Q80K frequencies in reads of samples subjected to Illumina sequencing were >40% in all cases. Among subjects with Q80K, five of 44 (11.4%) showed one additional major resistance-associated mutation in NS3, detected at frequencies of >10% (V36L and V55A) or <10% (V36M). Phylogenetic analyses identified the two recognized HCV-1a lineages with (clade I) and without (clade II) Q80K. Overall, 148 of 238 (62.2%) sequences occurred within regional or inter-regional clusters, each comprising 3-20 sequences. There was no unique clustering of English sequences relative to strains from continental Europe and North America. In conclusion, Q80K was found at a high prevalence among treatment-naïve HCV-1a carriers in England, and was reliably detected by conventional sequencing, with no increased detection by deep sequencing. English sequences were highly interspersed with sequences from elsewhere in Europe (clade II) and North America (clade I), and their phylogeny was consistent with multiple introductions from different areas. PMID:26232533

  8. UNOCAL Parachute Creek Shale Oil Program. Environmental monitoring plan quarterly report. First quarter 1988. Report for 1 January-31 March 1988

    SciTech Connect

    Not Available

    1988-05-31

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commercial-scale synthetic fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The support agreement included development of an Environmental Monitoring Plan incorporating existing compliance monitoring and supplemental monitoring on water, air, solid waste, worker health and safety, and socio-economic impacts during the period 1986-1993. Twenty-two supplemental monitoring sites have been designated, to date. This report describes ambient and source compliance data collected during the quarter, progress in performance monitoring, certification for air quality, monitoring audits, and initial industrial hygiene supplemental monitoring.

  9. Unocal Parachute Creek Shale Oil Program. Environmental Monitoring Plan quarterly report. Third quarter, 1989. Report for 1 July-30 September 1989

    SciTech Connect

    Not Available

    1989-11-30

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commercial-scale synthetic-fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The support agreement included development of and Environmental Monitoring Plan, incorporating existing compliance monitoring and supplemental monitoring on water, air, solid waste, worker health and safety, and socio economic impacts during the period 1986-1993. Phase I of the project is to produce 10,000 barrels per day of syncrude from oil shale, using the Unishale B process. A description of Compliance activities completed during the quarter and copies of agency reports are given in the document. Supplemental sampling for industrial hygiene also is described.

  10. UNOCAL: Parachute Creek Shale Oil Program. Environmental Monitoring Plan quarterly report. Fourth quarter 1987. Report for 1 October-31 December 1987

    SciTech Connect

    Not Available

    1988-02-29

    The Energy Security Act of 1980 established a program to provide financial assistance to private industry in the construction and operation of commercial-scale synthetic-fuels plants. The Parachute Creek Shale Oil Program is one of four projects awarded financial assistance. The support agreement included development of an Environmental Monitoring Plan, incorporating existing compliance monitoring and supplemental monitoring on water, air, solid waste, worker health and safety, and socio-economic impacts during the period 1986-1993. Phase I of this project is to produce 10,000 barrels per day of syncrude from oil shale, using the Unishale B process. During the fourth quarter, detailed analytical procedures and computer-data-management software were developed, sampling analytical and data-management standards were completed, and supplemental quality assurance and control programs were finalized. All of these activities are summarized in the report.

  11. A Historical Review of "Business Communication Quarterly."

    ERIC Educational Resources Information Center

    Lewis, Stephen D.

    2001-01-01

    Presents a brief history of the "Business Communication Quarterly" and its predecessors from 1936-2000. Investigates trends in topic coverage, and lists the journal's editors and most prolific authors. (SR)

  12. 14 CFR 93.325 - Quarterly reporting.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Special Flight Rules in the Vicinity of Grand Canyon National Park, AZ § 93.325 Quarterly reporting. (a) Each certificate holder must submit in...

  13. 14 CFR 93.325 - Quarterly reporting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Special Flight Rules in the Vicinity of Grand Canyon National Park, AZ § 93.325 Quarterly reporting. (a) Each certificate holder must submit in...

  14. 14 CFR 93.325 - Quarterly reporting.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Special Flight Rules in the Vicinity of Grand Canyon National Park, AZ § 93.325 Quarterly reporting. (a) Each certificate holder must submit in...

  15. Project financial evaluation

    SciTech Connect

    None, None

    2009-01-18

    The project financial section of the Renewable Energy Technology Characterizations describes structures and models to support the technical and economic status of emerging renewable energy options for electricity supply.

  16. Financial Literacy as the Foundation for Individual Financial Behavior

    ERIC Educational Resources Information Center

    Dwiastanti, Anis

    2015-01-01

    Research that is dealing with financial literacy turns to be such an important thing to be conducted. It is due to the fact that financial literacy level of Indonesian society is still very low. A good financial literacy is necessary for every individual to manage his/her finances to achieve prosperity. To have a good level of financial literacy,…

  17. AGEX II: Technical quarterly, Volume 2

    SciTech Connect

    Ekdahl, C.

    1995-03-01

    The AGEX II Technical Quarterly publishes short technical contributions on above ground experiments that use pulsed power and laser drivers. The Quarterly is intended to provide rapid exposure of timely technical ideas and results as well as a means for documenting AGEX II progress and scientific quality for the AGEX II community. Suitable topics include experimental results, diagnostic apparatus, theoretical design, and scaling, among others.

  18. Chaotic Financial Tornadoes

    NASA Astrophysics Data System (ADS)

    Jakimowicz, Aleksander

    In contemporary economies classic business cycles are increasingly changing their form undergoing a transformation into phenomena that have been nicknamed financial tornados. A generalization of the Lotka-Volterra model can be used to describe these fast-changing processes. Economically speaking, the most useful are such dynamical systems in which wormholes appear. This article features application of a model with one population of prey and two populations of predators in order to explain the global financial crisis and the consequent phenomena.

  19. Walking, cloning, and mapping with YACs in 3q27: Localization of five ESTs including three members of the cystatin gene family and identification of CpG islands

    SciTech Connect

    James, L.A.; Ogilvie, D.J.; Anand, R.

    1996-03-05

    Using yeast artificial chromosomes, we have generated a high-resolution physical map for 2.7 Mb of human chromosomal region 3q27. The YAC clones group into three contigs, one of which has also been linked to the CEPH YAC contig map of human chromosome 3. Fluorescence in situ hybridization has been used to order the contigs on the chromosome and to estimate the distance between them. Expressed sequence tags for five genes, including three members of the cystatin gene family and a gene thought to be involved in B-cell non-Hodgkin lymphoma, have been placed within the YAC contigs, and 12 putative CpG islands have been identified. These YACs provide a useful resource to complete the physical mapping of 3q27 and to begin identification and characterization of further genes that are located there. 27 refs., 1 fig., 1 tab.

  20. Analysis of a familial three way translocation involving chromosomes 3q, 6q, and 15q by high resolution banding and fluorescent in situ hybridisation (FISH) shows two different unbalanced karyotypes in sibs.

    PubMed Central

    Wieczorek, D; Engels, H; Viersbach, R; Henke, B; Schwanitz, G; Passarge, E

    1998-01-01

    We report on a familial three way translocation involving chromosomes 3, 6, and 15 identified by prometaphase banding and fluorescence in situ hybridisation (FISH). Two mentally retarded sibs with different phenotypic abnormalities, their phenotypically normal sister and mother, and two fetuses of the phenotypically normal sister were analysed. The terminal regions of chromosomes 3q, 6q, and 15q were involved in a reciprocal translocation, in addition to a paracentric inversion of the derivative chromosome 15. Conventional cytogenetic studies with high resolution GTG banding did not resolve this rearrangement. FISH using whole chromosome paints (WCPs) identified the chromosomal regions involved, except the aberrant region of 3q, which was undetectable with these probes. Investigation of this region with the subtelomeric FISH probe D3S1445/D3S1446 showed a balanced karyotype, 46,XX,t(3;15;6) (q29;q26.1;q26), inv der(15) (q15.1q26.1) in two adult females and one fetus. It was unbalanced in two sibs, showing two different types of unbalanced translocation resulting in partial trisomy 3q in combination with partial monosomy 6q in one patient and partial trisomy 15q with partial monosomy 6q in the other patient and one fetus. These represent apparently new chromosomal phenotypes. Images PMID:9678698

  1. 29 CFR 548.306 - Average earnings for year or quarter year preceding the current quarter.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Average earnings for year or quarter year preceding the... PAY Interpretations Authorized Basic Rates § 548.306 Average earnings for year or quarter year... hour for each workweek equal to the average hourly remuneration of the employee for employment...

  2. 29 CFR 548.306 - Average earnings for year or quarter year preceding the current quarter.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Average earnings for year or quarter year preceding the current quarter. 548.306 Section 548.306 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS AUTHORIZATION OF ESTABLISHED BASIC RATES FOR COMPUTING OVERTIME PAY Interpretations Authorized Basic Rates...

  3. Calorimetry exchange program. Quarterly data report, 2nd quarter 1992

    SciTech Connect

    Barnett, T.M.

    1996-07-01

    The goals of the Calorimetry Sample Exchange Program are: (1) Discuss measurement differences, (2) Review and improve analytical measurements and methods, (3) Discuss new measurement capabilities, (4) Provide data to DOE on measurement capabilities to evaluate shipper-receiver differences, (5) Provide characterized or standard materials as necessary for exchange participants, (6) Provide a measurement control program for plutonium analysis. A sample of PuO{sub 2} powder is available at each participating site for NDA measurement, including either or both calorimetry and high-resolution gamma-ray spectroscopy, the elements which are typically combined to provide a calorimetric assay of plutonium. The facilities measure the sample as frequently and to the level of precision which they desire, and then submit the data to the Exchange for analysis. Statistical tests are used to evaluate the data and to determine if there are significant differences from accepted values for the exchange sample or from data previously reported by that facility. This information is presented, in the form of a quarterly report, intended for use by Exchange participants in measurement control programs, or to indicate when bias corrections may be appropriate. No, attempt, however, has been made to standardize methods or frequency of data collection, calibration, or operating procedures. Direct comparisons between laboratories may, therefore, be misleading since data have not been collected to the same precision or for the same time periods. A meeting of the participants of the Calorimetry Exchange is held annually at EG&G Mound Applied Technologies. The purposes of this meeting are to discuss measurement differences, problems, and new measurement capabilities, and to determine the additional activities needed to fulfill the goals of the Exchange.

  4. Calorimetry exchange program. Quarterly data report, 1st quarter 1992

    SciTech Connect

    Barnett, T.M.

    1996-07-01

    The goals of the Calorimetry Sample Exchange Program are: (1) Discuss measurement differences, (2) Review and improve analytical measurements and methods, (3) Discuss new measurement capabilities, (4) Provide data to DOE on measurement capabilities to evaluate shipper-receiver differences, (5) Provide characterized or standard materials as necessary for exchange participants, (6) Provide a measurement control program for plutonium analysis. A sample of PuO{sub 2} powder is available at each participating site for NDA measurement, including either or both calorimetry and high-resolution gamma-ray spectroscopy, the elements which are typically combined to provide a calorimetric assay of plutonium. The facilities measure the sample as frequently and to the level of precision which they desire, and then submit the data to the Exchange for analysis. Statistical tests are used to evaluate the data and to determine if there are significant differences from accepted values for the exchange sample or from data previously reported by that facility. This information is presented, in the form of a quarterly report, intended for use by Exchange participants in measurement control programs, or to indicate when bias corrections may be appropriate. No attempt, however, has been made to standardize methods or frequency of data collection, calibration, or operating procedures. Direct comparisons between laboratories may, therefore, be misleading since data have not been collected to the same precision or for the same time periods. A meeting of the participants of the Calorimetry Exchange is held annually at EG&G Mound Applied Technologies. The purposes of this meeting are to discuss measurement differences, problems, and new measurement capabilities, and to determine the additional activities needed to fulfill the goals of the Exchange.

  5. Biomass power for rural development. Quarterly report, July 1--September 30, 1998

    SciTech Connect

    Cooper, J.T.

    1998-10-01

    In this quarter a large amount of time was spent doing project planning and budget preparation for the fiscal years 1998 and 1999. Many issues of long-term strategic planning and budgeting depend on the availability of Federal support, including financial, technical and political. It has become increasingly obvious that several significant barriers must be overcome in order to reach the final project goal of commercial replication of the technology. This report describes switchgrass conversion development, production activities, environmental analysis planning, and information and education. Appendices discuss the biomass project, sediment delivery, successful establishment of switchgrass, and legislative support for the biomass project.

  6. Correlates of financial satisfaction.

    PubMed

    Hsieh, C M

    2001-01-01

    The objectives of this study are to 1) assess the effects of major correlates of global subjective well-being on financial satisfaction, and 2) use empirical data to present the consequences of violating basic regression assumptions. Analyzing data from the General Social Surveys, 1972-1996 (Davis & Smith, 1996a) this study found that among Americans age forty-five and above, most of the major correlates of global subjective well-being show similar effects on financial satisfaction. The study's findings confirm a nonlinear effect of income on financial satisfaction. Comparing results from different analytical methods, this study also alerts researchers to the importance of taking into account the level of measurements of study variables, which have tended to be overlooked by previous subjective well-being research.

  7. Vector financial rogue waves

    NASA Astrophysics Data System (ADS)

    Yan, Zhenya

    2011-11-01

    The coupled nonlinear volatility and option pricing model presented recently by Ivancevic is investigated, which generates a leverage effect, i.e., stock volatility is (negatively) correlated to stock returns, and can be regarded as a coupled nonlinear wave alternative of the Black-Scholes option pricing model. In this Letter, we analytically propose vector financial rogue waves of the coupled nonlinear volatility and option pricing model without an embedded w-learning. Moreover, we exhibit their dynamical behaviors for chosen different parameters. The vector financial rogue wave (rogon) solutions may be used to describe the possible physical mechanisms for the rogue wave phenomena and to further excite the possibility of relative researches and potential applications of vector rogue waves in the financial markets and other related fields.

  8. Contextual view of Quarters 1 and 2, with landscape elements ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of Quarters 1 and 2, with landscape elements visible, camera facing southwest - Naval Training Station, Senior Officers' Quarters District, Naval Station Treasure Island, Yerba Buena Island, San Francisco, San Francisco County, CA

  9. ARM Operations Quarterly Report October 1-December 31, 2013

    SciTech Connect

    Voyles, Jimmy W.

    2013-12-31

    The U.S. Department of Energy requires national user facilities to report time-based operating data. This quarterly report is written to comply with this requirement. This reports on the first quarter facility statistics.

  10. STIRLING'S QUARTERS SMALL BARN: FIRST FLOOR PLAN; SECOND FLOOR PLAN; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    STIRLING'S QUARTERS SMALL BARN: FIRST FLOOR PLAN; SECOND FLOOR PLAN; SOUTH ELEVATION; EAST ELEVATION; NORTH ELEVATION; WEST ELEVATION. - Stirling's Quarters, 555 Yellow Springs Road, Tredyffrin Township, Valley Forge, Chester County, PA

  11. Contextual photograph of quarters no. 2 and tower, looking southeasterly ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual photograph of quarters no. 2 and tower, looking southeasterly from entrance road. - Sacramento National Wildlife Refuge, Headquarters Complex, Quarters No. 2, 752 County Road 99W, Willows, Glenn County, CA

  12. Contextual view of district with Quarters 1, 2, and 3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of district with Quarters 1, 2, and 3 in view, as well as Whiting Way, camera facing southwest - Naval Training Station, Senior Officers' Quarters District, Naval Station Treasure Island, Yerba Buena Island, San Francisco, San Francisco County, CA

  13. 2. EAST SIDE OF SLAVE QUARTERS (Jack E. Boucher, photgrapher, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. EAST SIDE OF SLAVE QUARTERS (Jack E. Boucher, photgrapher, April/May, 1986) - Felix & Odile Pratt Valle Slave Quarters, Southeast corner of Merchant & Second Streets, Sainte Genevieve, Ste. Genevieve County, MO

  14. Idaho National Laboratory Quarterly Performance Analysis

    SciTech Connect

    Lisbeth Mitchell

    2014-11-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 60 reportable events (23 from the 4th Qtr FY14 and 37 from the prior three reporting quarters) as well as 58 other issue reports (including not reportable events and Significant Category A and B conditions) identified at INL from July 2013 through October 2014. Battelle Energy Alliance (BEA) operates the INL under contract DE AC07 051D14517.

  15. New Financial Models.

    ERIC Educational Resources Information Center

    Taylor, Michael G.

    1991-01-01

    This report synthesizes experiences in a number of countries (United Kingdom, Netherlands, Germany, Australia, Japan) on the market economy in higher education. Considered are market forces, various financial structures (institutional budgets, student funding, research infrastructure, other income, staffing), and implications for the future. (MSE)

  16. EERE Financial Opportunities

    SciTech Connect

    2012-04-19

    The Office of Energy Efficiency and Renewable Energy (EERE) works with business, industry, universities, and others to increase the use of renewable energy and energy efficiency technologies. One way EERE encourages the growth of these technologies is by offering financial assistance opportunities for their development and demonstration.

  17. Increasing Financial Security

    ERIC Educational Resources Information Center

    Kiss, Elizabeth

    2006-01-01

    Earning, spending, saving and investing, and using credit are important aspects of money management that teens need to understand as they move into adulthood. Family and consumer sciences (FCS) professionals have a long history of addressing this important life skill. This brief article describes the High School Financial Planning Program (HSFPP),…

  18. Issue of Financial Capability

    ERIC Educational Resources Information Center

    Hasek, Roman; Petraskova, Vladimira

    2010-01-01

    For most people, including students, it is not easy to have a good grasp of the basic terms in the field of finance and of their interrelations, in particular due to the fact that the offer for financial products keeps changing and its statement is frequently unclear, insincere and confusing. The Pedagogical Faculty of the University of South…

  19. Financial Management Assistant.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This publication contains 19 subjects appropriate for use in a competency list for the occupation of financial management assistant, 1 of 12 occupations within the business/computer technologies cluster. Each unit consists of a number of competencies; a list of competency builders is provided for each competency. Titles of the 19 units are as…

  20. Coping with Financial Distress

    ERIC Educational Resources Information Center

    Chabotar, Kent John

    2007-01-01

    Colleges and universities, like corporations and other nonprofit organizations, are subject to periodic fluctuations in the economy and public support. Thus, the question is not whether they will confront financial problems but rather when and how. This article describes how institutions and boards can detect budgets in crisis, provides principles…

  1. Hawaiian Volcano Observatory 1956 Quarterly Administrative Reports

    USGS Publications Warehouse

    Nakata, Jennifer S.

    2007-01-01

    The Hawaiian Volcano Observatory Summaries have been published in the current format since 1956. The Quarterly Summaries (1956 through 1973) and the Annual Summaries (1974 through 1985) were originally published as Administrative Reports. These reports have been compiled and published as U.S. Geological Survey Open-File Reports. The quarterly reports have been combined and published as one annual summary. All the summaries from 1956 to the present are now available as .pdf files at http://www.usgs.gov/pubprod. This report consists of four parts.

  2. Financial Planners: Educating Widows in Personal Financial Planning

    ERIC Educational Resources Information Center

    Korb, Brian R.

    2010-01-01

    Widows constitute a growing segment of the U.S. population; however, very little has been done to educate them on the basics of personal financial planning. The creation and implementation of financial planning education programs for widows can help them become more financially literate and free them from anxiety and fear. Interviews with eight…

  3. Inmate Perceptions of Financial Education Needs: Suggestions for Financial Educators

    ERIC Educational Resources Information Center

    Call, Lindsay Larson; Dyer, W. Justin; Wiley, Angela R.; Day, Randal D.

    2013-01-01

    Recently, national attention has turned to the need for increased financial education, particularly for low-income populations. Incarcerated individuals represent a growing low-income group with unique needs that could likely benefit from financial education. However, few studies have examined the specific financial education needs of inmates,…

  4. Financial Stress and Financial Counseling: Helping College Students

    ERIC Educational Resources Information Center

    Britt, Sonya L.; Canale, Anthony; Fernatt, Fred; Stutz, Kristen; Tibbetts, Racquel

    2015-01-01

    This study had two distinct purposes. First, to determine the predictors of financial stress among college students who sought free peer-based financial counseling from a large Midwestern university (N = 675). Secondly, to determine the effectiveness of the particular financial counseling center from a subsample of those who sought help (N = 97).…

  5. Workplace Financial Education Facilitates Improvement in Personal Financial Behaviors

    ERIC Educational Resources Information Center

    Prawitz, Aimee D.; Cohart, Judith

    2014-01-01

    Based on the life-cycle theory of consumption, this quasi-experimental study of 995 employees examined changes in financial behaviors following employee-needs-driven workplace financial education. Repeated-measures ANOVA compared participants and non-participants on perceived financial wellness and savings ratios; main effects indicated that both…

  6. South elevation of Superintendent's Quarters, built as a combination staff ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    South elevation of Superintendent's Quarters, built as a combination staff living quarters/office and a visitor reception room by the War Department in 1923-24. Note exterior door to Gold Star Mothers' reception room on right. - Flanders Field American Cemetery & Memorial, Superintendent's Quarters, Wortegemseweg 117, Waregem, West Flanders (Belgium)

  7. 46 CFR 72.25-10 - Location of passenger quarters.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 3 2014-10-01 2014-10-01 false Location of passenger quarters. 72.25-10 Section 72.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS CONSTRUCTION AND ARRANGEMENT Passenger Accommodations § 72.25-10 Location of passenger quarters. (a) The deck forming the deckhead of passenger quarters...

  8. 46 CFR 72.25-10 - Location of passenger quarters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 3 2012-10-01 2012-10-01 false Location of passenger quarters. 72.25-10 Section 72.25-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS CONSTRUCTION AND ARRANGEMENT Passenger Accommodations § 72.25-10 Location of passenger quarters. (a) The deck forming the deckhead of passenger quarters...

  9. Natural gas imports and exports. Second quarter report

    SciTech Connect

    1997-12-31

    The Office of Natural Gas and Petroleum Import and Export Activities prepares quarterly reports summarizing the data provided by companies authorized to import or export natural gas. Companies are required, as a condition of their authorizations, to file quarterly reports. This report is for the second quarter of 1997 (April through June).

  10. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TREASURY (CONTINUED) LIQUIDATION OF DUTIES Conversion of Foreign Currency § 159.34 Certified quarterly rate. (a) Countries for which quarterly rate is certified. For the currency of each of the following... York for such foreign currency for a day in that quarter: Australia, Austria, Belgium, Brazil,...

  11. 12 CFR 620.10 - Preparing the quarterly report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Preparing the quarterly report. 620.10 Section 620.10 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM DISCLOSURE TO SHAREHOLDERS Quarterly Report § 620.10 Preparing the quarterly report. (a) Each institution of the Farm Credit...

  12. Financial Literacy Education for Women

    ERIC Educational Resources Information Center

    Jarecke, Jodi; Taylor, Edward W.; Hira, Tahira K.

    2014-01-01

    Exploring the pedagogical approaches of four women's financial literacy education programs, this chapter provides an overview of trends and needs in financial education for women and offers pedagogical strategies for teaching women about finance.

  13. Financial Management: An Organic Approach

    ERIC Educational Resources Information Center

    Laux, Judy

    2013-01-01

    Although textbooks present corporate finance using a topical approach, good financial management requires an organic approach that integrates the various assignments financial managers confront every day. Breaking the tasks into meaningful subcategories, the current article offers one approach.

  14. Radiology applications of financial accounting.

    PubMed

    Leibenhaut, Mark H

    2005-03-01

    A basic knowledge of financial accounting can help radiologists analyze business opportunities and examine the potential impacts of new technology or predict the adverse consequences of new competitors entering their service area. The income statement, balance sheet, and cash flow statement are the three basic financial statements that document the current financial position of the radiology practice and allow managers to monitor the ongoing financial operations of the enterprise. Pro forma, or hypothetical, financial statements can be generated to predict the financial impact of specific business decisions or investments on the profitability of the practice. Sensitivity analysis, or what-if scenarios, can be performed to determine the potential impact of changing key revenue, investment, operating cost or financial assumptions. By viewing radiology as both a profession and a business, radiologists can optimize their use of scarce economic resources and maximize the return on their financial investments.

  15. Radiology applications of financial accounting.

    PubMed

    Leibenhaut, Mark H

    2005-03-01

    A basic knowledge of financial accounting can help radiologists analyze business opportunities and examine the potential impacts of new technology or predict the adverse consequences of new competitors entering their service area. The income statement, balance sheet, and cash flow statement are the three basic financial statements that document the current financial position of the radiology practice and allow managers to monitor the ongoing financial operations of the enterprise. Pro forma, or hypothetical, financial statements can be generated to predict the financial impact of specific business decisions or investments on the profitability of the practice. Sensitivity analysis, or what-if scenarios, can be performed to determine the potential impact of changing key revenue, investment, operating cost or financial assumptions. By viewing radiology as both a profession and a business, radiologists can optimize their use of scarce economic resources and maximize the return on their financial investments. PMID:17411807

  16. 76 FR 46781 - Commission Information Collection Activities (FERC Form 1 and FERC Form 1F); Comment Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ..., and 3Q \\2\\. The FERC Annual/Quarterly Report Forms provide the Commission, as well as others, with an... financial and operating report submitted for electric rate regulation and financial audits. Major is defined as having (1) One million Megawatt hours or more; (2) 100 megawatt hours of annual sales for...

  17. "Financial Bubbles" and Monetary Policy

    ERIC Educational Resources Information Center

    Tikhonov, Yuriy A.; Pudovkina, Olga E.; Permjakova, Juliana V.

    2016-01-01

    The relevance of this research is caused by the need of strengthening a role of monetary regulators to prevent financial bubbles in the financial markets. The aim of the article is the analysis of a problem of crisis phenomena in the markets of financial assets owing to an inadequate growth of their cost, owing to subjective reasons. The leading…

  18. Strategic Planning and Financial Management

    ERIC Educational Resources Information Center

    Conneely, James F.

    2010-01-01

    Strong financial management is a strategy for strategic planning success in student affairs. It is crucial that student affairs professionals understand the necessity of linking their strategic planning with their financial management processes. An effective strategic planner needs strong financial management skills to implement the plan over…

  19. Erecting a Sturdy Financial Structure.

    ERIC Educational Resources Information Center

    West, Jeffrey J.

    1998-01-01

    Explanation of the technological setting in which college and university financial systems have developed is provided for financial officers, to aid in devising a plan for the chart of accounts and erecting an efficient, logical, flexible financial structure. Topics include software/hardware advances, understanding the demand for financial…

  20. Sea Level did not Accelerate in the Last Quarter of the 20th Century

    NASA Astrophysics Data System (ADS)

    Galvin, C.

    2004-12-01

    sea-level rise during Q4, when the reported beach erosion increased, compared to during Q3, Q2, or Q1.

  1. Idaho National Laboratory Quarterly Performance Analysis - 3rd Quarter FY2014

    SciTech Connect

    Lisbeth A. Mitchell

    2014-09-01

    This report is published quarterly by the Idaho National Laboratory (INL) Performance Assurance Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of occurrence reports and other non-reportable issues identified at INL from July 2013 through June 2014.

  2. Idaho National Laboratory Quarterly Performance Analysis for the 2nd Quarter FY 2015

    SciTech Connect

    Mitchell, Lisbeth A.

    2015-04-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of events for the 2nd Qtr FY-15.

  3. A financial network perspective of financial institutions' systemic risk contributions

    NASA Astrophysics Data System (ADS)

    Huang, Wei-Qiang; Zhuang, Xin-Tian; Yao, Shuang; Uryasev, Stan

    2016-08-01

    This study considers the effects of the financial institutions' local topology structure in the financial network on their systemic risk contribution using data from the Chinese stock market. We first measure the systemic risk contribution with the Conditional Value-at-Risk (CoVaR) which is estimated by applying dynamic conditional correlation multivariate GARCH model (DCC-MVGARCH). Financial networks are constructed from dynamic conditional correlations (DCC) with graph filtering method of minimum spanning trees (MSTs). Then we investigate dynamics of systemic risk contributions of financial institution. Also we study dynamics of financial institution's local topology structure in the financial network. Finally, we analyze the quantitative relationships between the local topology structure and systemic risk contribution with panel data regression analysis. We find that financial institutions with greater node strength, larger node betweenness centrality, larger node closeness centrality and larger node clustering coefficient tend to be associated with larger systemic risk contributions.

  4. Augmented Reality for Close Quarters Combat

    ScienceCinema

    None

    2016-07-12

    Sandia National Laboratories has developed a state-of-the-art augmented reality training system for close-quarters combat (CQB). This system uses a wearable augmented reality system to place the user in a real environment while engaging enemy combatants in virtual space (Boston Dynamics DI-Guy). Umbra modeling and simulation environment is used to integrate and control the AR system.

  5. 77 FR 24505 - ACHP Quarterly Business Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... From the Federal Register Online via the Government Publishing Office ADVISORY COUNCIL ON HISTORIC PRESERVATION ACHP Quarterly Business Meeting AGENCY: Advisory Council on Historic Preservation. ACTION: Notice... Office Closures and Disposal IX. New Business X. Adjourn Note: The meetings of the ACHP are open to...

  6. 77 FR 3784 - ACHP Quarterly Business Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... From the Federal Register Online via the Government Publishing Office ADVISORY COUNCIL ON HISTORIC PRESERVATION ACHP Quarterly Business Meeting AGENCY: Advisory Council on Historic Preservation. ACTION: Notice... Implementation C. Bureau of Land Management Nationwide Programmatic Agreement VIII. New Business IX. Adjourn...

  7. Quarterly Coal Report, April-June 1985

    SciTech Connect

    Not Available

    1985-10-18

    The Quarterly Coal Report provides comprehensive information about coal production, exports, imports, receipts, consumption, and stocks in the United States. The data presented in this report were collected and published by the Energy Information Administration (EIA) to fulfill its data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (P.L. 93-275) as amended. This issue shows detailed quarterly data for April-June 1985, aggregated quarterly historical and projected data for 1980 through 1986, and aggregated annual historical and projected data for 1960 through 1995. All data for 1984 and previous years are final. All 1985 data are preliminary and subject to revision. During the first and second quarters of 1985, the US coal industry continued to return to normal operations after the threat of a strike by US coal miners in 1984. For the first 6 months of 1985 the industry showed the following developments: Coal production was only 2.4% less than in the same period of 1984, when it reached a record January-June total. Coal exports were 10.0% higher than their 1984 level for the same time period. The United States imported 52.3% more coal than it did in the first 6 months of 1984, chiefly from Colombia. Domestic coal consumption reached a record-setting level for January-June, 3.6% greater than the previous record in 1984.

  8. Quarterly coal report, April 1995--June 1995

    SciTech Connect

    1995-11-01

    This document provides comprehensive information about U.S. coal production, distribution, imports, exports, prices, and consumption. Coke production, consumption, distribution, imports, and exports are also provided. This report presents compiled data for April thru June, and historical data for 1987 thru the first quarter of 1995.

  9. 46 CFR 122.724 - Quarterly inspections.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Quarterly inspections. 122.724 Section 122.724 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150 PASSENGERS OR WITH OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS OPERATIONS Operational Readiness, Maintenance, and Inspection...

  10. "The Career Development Quarterly": A Centennial Retrospective

    ERIC Educational Resources Information Center

    Savickas, Mark L.; Pope, Mark; Niles, Spencer G.

    2011-01-01

    "The Career Development Quarterly" has been the premier journal in the field of vocational guidance and career intervention since its inception 100 years ago. To celebrate its centennial, 3 former editors trace its evolution from a modest and occasional newsletter to its current status as a major professional journal. They recount its history of…

  11. Washington Community Colleges Fall Quarter Report, 1982.

    ERIC Educational Resources Information Center

    Story, Sherie; And Others

    Information on enrollments and student characteristics at Washington state community colleges is provided in this report for fall 1982. After introductory material and report highlights, tables provide data on headcount and full-time equivalent (FTE) enrollment for fall quarters 1978 through 1982; FTE and headcount by course intent category;…

  12. English Leadership Quarterly, 2002-2003.

    ERIC Educational Resources Information Center

    Wilcox, Bonita L., Ed.

    2003-01-01

    This 25th volume of "English Leadership Quarterly" contains articles on topics of interest to those in positions of leadership in departments (elementary, secondary, or college) where English is taught. Each issue focuses on a different theme. Articles in Volume 25 Number 1 focus on leadership and literacy and are: "Research Summary of a Best…

  13. English Leadership Quarterly, 2000-2001.

    ERIC Educational Resources Information Center

    Kiernan, Henry, Ed.

    2001-01-01

    This 23rd volume of "English Leadership Quarterly" contains articles on topics of interest to those in positions of leadership in departments (elementary, secondary, or college) where English is taught. Each issue focuses on a different theme. Articles in Volume 23 Number 1 are: "Block Scheduling and Student Achievement" (Elizabeth Howard); "Block…

  14. 9 CFR 332.8 - Quarterly reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Quarterly reports. 332.8 Section 332.8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION...

  15. 9 CFR 332.8 - Quarterly reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Quarterly reports. 332.8 Section 332.8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION...

  16. English Leadership Quarterly, 1997-1998.

    ERIC Educational Resources Information Center

    Kiernan, Henry, Ed.

    1998-01-01

    These six theme issues of the "English Leadership Quarterly" represent those published during 1997 and part of 1998--volume 19 consists of the traditional four issues, while volume 20 consists of only two issues because of a change in publication schedule. Articles in volume 19 number 1 deal with theories, issues, and personal accounts on the…

  17. Conducting First Quarter Labs with Few Chemicals.

    ERIC Educational Resources Information Center

    Kelly, Michael J.

    2002-01-01

    Outlines chemistry labs used during the first quarter of study and advises about framing the course for students. Topics of the labs include observation; blind observation; measurement, determination of conversion factors, and percent error; taking and reporting data over time; and density. (DDR)

  18. Student Affairs and Services Stream: College Quarterly

    ERIC Educational Resources Information Center

    Buddel, Neil

    2015-01-01

    "College Quarterly" recently introduced a stream for academic and scholar-practitioner dialogue concerning student affairs and services. To contribute to the growth and enhancement of the field, scholars and scholar-practitioners are invited to contribute original pieces that advance scholarship and/or practice around facilitating…

  19. Augmented Reality for Close Quarters Combat

    SciTech Connect

    2013-09-20

    Sandia National Laboratories has developed a state-of-the-art augmented reality training system for close-quarters combat (CQB). This system uses a wearable augmented reality system to place the user in a real environment while engaging enemy combatants in virtual space (Boston Dynamics DI-Guy). Umbra modeling and simulation environment is used to integrate and control the AR system.

  20. RTO Technical Publications: A Quarterly Listing

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This is a listing of recent unclassified RTO technical publications processed by the NASA Center for AeroSpace Information. Contents include the following: RTO Technical Publications: A Quarterly Listing. Implications of Multilingual Interoperability of Speech Technology for Military Use. Non-Lethal Weapons and Future Peace Enforcement Operations.

  1. Trustee Quarterly, Issues 1-3, 1996.

    ERIC Educational Resources Information Center

    Hutchins, Sally, Ed.

    1996-01-01

    The three issues of "Trustee Quarterly" contained in this document focus on topics of current concern to community college trustees. Issue 1 for 1996 focuses on the policy governance model of community college board leadership, offering the following feature articles: "John Carver...and His Contribution to Community College Governance," (Ray…

  2. 14 CFR 93.325 - Quarterly reporting.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Quarterly reporting. 93.325 Section 93.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Special Flight Rules in the Vicinity of Grand Canyon National Park, AZ §...

  3. Subject Access Project. Second Quarterly Progress Report.

    ERIC Educational Resources Information Center

    Atherton, Pauline

    The Subject Access Project second quarterly report for September to December 1976 summarized in-progress work to improve subject access to monographs. Activities include: (1) analysis of book indexes and tables of contents for terms to augment MARC subject description; (2) analysis of additional book sections--e.g., maps, illustrations, charts,…

  4. "Library Quarterly" Management Literature, 1931-2004

    ERIC Educational Resources Information Center

    Young, Arthur P.

    2006-01-01

    Management literature appearing in "Library Quarterly," 1931-2004, is examined in this essay. A total of 145 articles are identified that focus on administrative and managerial issues related to libraries during this period. Management literature is construed expansively and includes accounting, administration, assessment, budgets, facilities,…

  5. Environmental Biosciences Program Quarterly Report

    SciTech Connect

    Lawrence C. Mohr, M.D.

    2009-01-30

    Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on several trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River

  6. Quarterly coal report July--September 1996, February 1997

    SciTech Connect

    1997-02-01

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. This report presents detailed quarterly data for July through September 1996 and aggregated quarterly historical data for 1990 through the second quarter of 1996. Appendix A displays, from 1988 on, detailed quarterly historical coal imports data. 8 figs., 72 tabs.

  7. Communication impacting financial markets

    NASA Astrophysics Data System (ADS)

    Vitting Andersen, Jørgen; Vrontos, Ioannis; Dellaportas, Petros; Galam, Serge

    2014-10-01

    Since the attribution of the Nobel prize in 2002 to Kahneman for prospect theory, behavioral finance has become an increasingly important subfield of finance. However the main parts of behavioral finance, prospect theory included, understand financial markets through individual investment behavior. Behavioral finance thereby ignores any interaction between participants. We introduce a socio-financial model (Vitting Andersen J. and Nowak A., An Introduction to Socio-Finance (Springer, Berlin) 2013) that studies the impact of communication on the pricing in financial markets. Considering the simplest possible case where each market participant has either a positive (bullish) or negative (bearish) sentiment with respect to the market, we model the evolution of the sentiment in the population due to communication in subgroups of different sizes. Nonlinear feedback effects between the market performance and changes in sentiments are taken into account by assuming that the market performance is dependent on changes in sentiments (e.g., a large sudden positive change in bullishness would lead to more buying). The market performance in turn has an impact on the sentiment through the transition probabilities to change an opinion in a group of a given size. The idea is that if for example the market has observed a recent downturn, it will be easier for even a bearish minority to convince a bullish majority to change opinion compared to the case where the meeting takes place in a bullish upturn of the market. Within the framework of our proposed model, financial markets stylized facts such as volatility clustering and extreme events may be perceived as arising due to abrupt sentiment changes via ongoing communication of the market participants. The model introduces a new volatility measure which is apt of capturing volatility clustering and from maximum-likelihood analysis we are able to apply the model to real data and give additional long term insight into where a market is

  8. College Students and Financial Distress: Exploring Debt, Financial Satisfaction, and Financial Anxiety

    ERIC Educational Resources Information Center

    Archuleta, Kristy L.; Dale, Anita; Spann, Scott M.

    2013-01-01

    The impact of financial concerns on overall mental health has become a popular topic among researchers and practitioners. In this exploratory study, possible associations of financial anxiety were explored using a sample of 180 college students who sought services at a university peer financial counseling center in a Midwestern state. Of…

  9. Integrated Financial Management Program

    NASA Technical Reports Server (NTRS)

    Pho, Susan

    2004-01-01

    Having worked in the Employees and Commercial Payments Branch of the Financial Management Division for the past 3 summers, I have seen the many changes that have occurred within the NASA organization. As I return each summer, I find that new programs and systems have been adapted to better serve the needs of the Center and of the Agency. The NASA Agency has transformed itself the past couple years with the implementation of the Integrated Financial Management Program (IFMP). IFMP is designed to allow the Agency to improve its management of its Financial, Physical, and Human Resources through the use of multiple enterprise module applications. With my mentor, Joseph Kan, being the branch chief of the Employees and Commercial Payments Branch, I have been exposed to several modules, such as Travel Manager, WebTads, and Core Financial/SAP, which were implemented in the last couple of years under the IFMP. The implementation of these agency-wide systems has sometimes proven to be troublesome. Prior to IFMP, each NASA Center utilizes their own systems for Payroll, Travel, Accounts Payable, etc. But with the implementation of the Integrated Financial Management Program, all the "legacy" systems had to be eliminated. As a result, a great deal of enhancement and preparation work is necessary to ease the transformation from the old systems to the new. All this work occurs simultaneously; for example, e-Payroll will "go live" in several months, but a system like Travel Manager will need to have information upgraded within the system to meet the requirements set by Headquarters. My assignments this summer have given me the opportunity to become involved with such work. So far, I have been given the opportunity to participate in projects resulting from a congressional request, several bankcard reconciliations, updating routing lists for Travel Manager, updating the majordomo list for Travel Manager approvers and point of contacts, and a NASA Headquarters project involving

  10. Measuring financial performance: an overview of financial statements.

    PubMed

    Dalsted, N L

    1995-07-01

    Financial management has emerged as a critical component in the long-term viability of today's ranches and farms. Proper and timely financial reporting and analysis of financial statements are valuable tools that agricultural producers can use to monitor, coordinate, and plan their operational production and marketing schemes and strategies. A side note to preparation of financial statements. With the concerns over lender liability issues associated with statements either assisted with or prepared by a lending officer, agricultural producers will be responsible for preparing their own statements. The lending institutions may prepare their own statements in their assessment of the financial condition of a business and or individual, but, ultimately, the responsibility of financial statements is the borrower's. Some of the material presented in this article provides important input for use in such analytical programs as the National Cattlemen's Association, Integrated Resource Committees, and Standard Performance Analysis (SPA). SPA techniques and associated software have been or currently are under development for cow-calf, stocker, seedstock, and sheep enterprises. Critical to the analysis is having complete and correct financial statements. These analytical programs build on the financial statements. These analytical programs build on the financial statements as recommended by the FFSTF. Proper financial reporting is critical not only to a SPA assessment but also to the overall financial management of today's farms and ranches. Recognizing the importance of financial management in production agriculture is not enough, taking a proactive stance in one's financial plan is paramount to success. Failure to do so will only enhance the exit rates of producers from production agriculture.

  11. Measuring financial performance: an overview of financial statements.

    PubMed

    Dalsted, N L

    1995-07-01

    Financial management has emerged as a critical component in the long-term viability of today's ranches and farms. Proper and timely financial reporting and analysis of financial statements are valuable tools that agricultural producers can use to monitor, coordinate, and plan their operational production and marketing schemes and strategies. A side note to preparation of financial statements. With the concerns over lender liability issues associated with statements either assisted with or prepared by a lending officer, agricultural producers will be responsible for preparing their own statements. The lending institutions may prepare their own statements in their assessment of the financial condition of a business and or individual, but, ultimately, the responsibility of financial statements is the borrower's. Some of the material presented in this article provides important input for use in such analytical programs as the National Cattlemen's Association, Integrated Resource Committees, and Standard Performance Analysis (SPA). SPA techniques and associated software have been or currently are under development for cow-calf, stocker, seedstock, and sheep enterprises. Critical to the analysis is having complete and correct financial statements. These analytical programs build on the financial statements. These analytical programs build on the financial statements as recommended by the FFSTF. Proper financial reporting is critical not only to a SPA assessment but also to the overall financial management of today's farms and ranches. Recognizing the importance of financial management in production agriculture is not enough, taking a proactive stance in one's financial plan is paramount to success. Failure to do so will only enhance the exit rates of producers from production agriculture. PMID:7584816

  12. Fault Geomechanics and Carbon Dioxide Leakage Applied to Geological Storage: FY07 Quarterly and Summary Reports

    SciTech Connect

    Friedmann, S J; Morris, J

    2007-11-02

    Safe and permanent storage of carbon dioxide in geologic reservoirs is critical to geologic sequestration. The objective of this study is to quantify the conditions under which a general (simulated) fault network and a specific (field case) fault network will fail and leak carbon dioxide out of a reservoir. Faults present a potential fast-path for CO{sub 2} leakage from reservoirs to the surface. They also represent potential induced seismicity hazards. It is important to have improved quantitative understandings of the processes that trigger activity on faults and the risks they present. Fortunately, the conditions under which leakage along faults is induced can be predicted and quantified given the fault geometry, reservoir pressure, an in-situ stress tensor. We proposed to expand the current capabilities of fault threshold characterization and apply that capability to a site where is CO{sub 2} injection is active or planned. Specifically, we proposed to use a combination of discrete/explicit and continuum/implicit codes to provide constrain the conditions of fault failure. After minor enhancements of LLNL's existing codes (e.g., LDEC), we would create a 3D synthetic model of a common configuration (e.g., a faulted dome). During these steps, we will identify a field site where the necessary information is available and where the operators are willing to share the necessary information. We would then execute an analysis specific to the field case. The primary products by quarter are: 1Q--Identification of likely field case; 2Q--Functioning prototype fault model; 3Q--Execution of fault-slip/migration calculation for synthetic case; and 4Q--Begin simulation of fault-slip/migration calculation for field system. It is worth noting that due to the continuing resolution, we did not receive any funds until 3Q, and did not receive >65% of the support until 4Q. That said, we were still able to meet all of our milestones for FY07 on time and on budget.

  13. Financial Literacy, Financial Education and Economic Outcomes. NBER Working Paper No. 18412

    ERIC Educational Resources Information Center

    Hastings, Justine S.; Madrian, Brigitte C.; Skimmyhorn, William L.

    2012-01-01

    In this article we review the literature on financial literacy, financial education, and consumer financial outcomes. We consider how financial literacy is measured in the current literature, and examine how well the existing literature addresses whether financial education improves financial literacy or personal financial outcomes. We discuss the…

  14. Review of the Proposed Quarterly Coal Review

    SciTech Connect

    Not Available

    1981-04-01

    This Review of the Proposed Quarterly Coal Review is the second of two reports and contains the results of our analysis of issues regarding the publication of a new summary publication, the Quarterly Coal Review. The first report on the QCR was submitted to the Office of Energy Data Operations (OEDO) in January 1981 and included results of our analysis and recommendations concerning data availability and content organization. This report concentrates on data presentation and publication format for the proposed QCR. Comprised of two sections, the report addresses chapter and table formats and presents a detailed analysis of chapter content. The first section of this report, Chapter, Table and Graph Formats, consists of findings and recommendations on the ordering, titling, end notes and cosmetics of the tables proposed for the QCR. The next section, Detailed Analysis of Chapter Content, is the result of a more in-depth analysis of chapters in the QCR.

  15. Recession trims third-quarter building costs

    SciTech Connect

    Morgan, J.M.

    1983-05-09

    The composite cost index for building oil pipelines during the third quarter of 1982 showed a decrease of 0.96%. This decrease was due to a steady drop in the rate of inflation for most pipeline construction materials during the first 9 months of the year. The major thrust behind the pipeline materials decline was a sharp 5.3% drop in the average price of steel line pipe. However, the pipeline construction recession has failed to deter escalating pipeline labor rates.

  16. Empowering Physicians with Financial Literacy.

    PubMed

    Bar-Or, Yuval

    2015-01-01

    Most doctors complete their medical training without sufficient knowledge of business and finance. This leads to inefficient financial decisions, avoidable losses, and unnecessary anxiety. A big part of the problem is that the existing options for gaining financial knowledge are flawed. The ideal solution is to provide a simple framework of financial literacy to all students: one that can be adapted to their specific circumstances. That framework must be delivered by an objective expert to young physicians before they complete medical training.

  17. Financial accounting for radiology executives.

    PubMed

    Seidmann, Abraham; Mehta, Tushar

    2005-03-01

    The authors review the role of financial accounting information from the perspective of a radiology executive. They begin by introducing the role of pro forma statements. They discuss the fundamental concepts of accounting, including the matching principle and accrual accounting. The authors then explore the use of financial accounting information in making investment decisions in diagnostic medical imaging. The paper focuses on critically evaluating the benefits and limitations of financial accounting for decision making in a radiology practice.

  18. 2nd Quarter Transportation Report FY 2014

    SciTech Connect

    Gregory, L.

    2014-07-01

    This report satisfies the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) commitment to prepare a quarterly summary report of radioactive waste shipments to the Nevada National Security Site (NNSS) Radioactive Waste Management Complex (RWMC) at Area 5. There were no shipments sent for offsite treatment and returned to the NNSS this quarter. This report summarizes the second quarter of fiscal year (FY) 2014 low-level radioactive waste (LLW) and mixed low-level radioactive waste (MLLW) shipments. This report also includes annual summaries for FY 2014 in Tables 4 and 5. Tabular summaries are provided which include the following: Sources of and carriers for LLW and MLLW shipments to and from the NNSS; Number and external volume of LLW and MLLW shipments; Highway routes used by carriers; and Incident/accident data applicable to LLW and MLLW shipments. In this report shipments are accounted for upon arrival at the NNSS, while disposal volumes are accounted for upon waste burial. The disposal volumes presented in this report do not include minor volumes of non-radioactive materials that were approved for disposal. Volume reports showing cubic feet (ft3) generated using the Low-Level Waste Information System may vary slightly due to differing rounding conventions.

  19. International Space Station USOS Crew Quarters Development

    NASA Technical Reports Server (NTRS)

    Broyan, James Lee, Jr.; Borrego, Melissa Ann; Bahr, Juergen F.

    2008-01-01

    The International Space Station (ISS) United States Operational Segment (USOS) currently provides a Temporary Sleep Station (TeSS) as crew quarters for one crewmember in the Laboratory Module. The Russian Segment provides permanent crew quarters (Kayutas) for two crewmembers in the Service Module. The TeSS provides limited electrical, communication, and ventilation functionality. A new permanent rack sized USOS ISS Crew Quarters (CQ) is being developed. Up to four CQs can be installed into the Node 2 element to increase the ISS crewmember size to six. The new CQs will provide private crewmember space with enhanced acoustic noise mitigation, integrated radiation reduction material, controllable airflow, communication equipment, redundant electrical systems, and redundant caution and warning systems. The rack sized CQ is a system with multiple crewmember restraints, adjustable lighting, controllable ventilation, and interfaces that allow each crewmember to personalize their CQ workspace. Providing an acoustically quiet and visually isolated environment, while ensuring crewmember safety, is critical for obtaining crewmember rest and comfort to enable long term crewmember performance. The numerous human factor, engineering, and program considerations during the concept, design, and prototyping are outlined in the paper.

  20. Income, age and financial satisfaction.

    PubMed

    Hsieh, Chang-ming

    2003-01-01

    Although the effects of income and age on subjective well-being have been widely studied, research on the effects of income and age on financial satisfaction, a major life domain to which income has direct relevance, remains limited. Analyzing data from the General Social Surveys, this article empirically examined the effects of income and age on financial satisfaction. These findings suggest that the social-psychological mechanisms underlying the age differences in the effects of income on financial satisfaction might not reflect a clear-cut status attainment versus status maintenance framework. The findings also served to caution future financial satisfaction research in the choice of income measures and the age grouping.

  1. Welfare Gains from Financial Liberalization

    PubMed Central

    Townsend, Robert M.; Ueda, Kenichi

    2010-01-01

    Financial liberalization has been a controversial issue, as empirical evidence for growth enhancing effects is mixed. Here, we find sizable welfare gains from liberalization (cost to repression), though the gain in economic growth is ambiguous. We take the view that financial liberalization is a government policy that alters the path of financial deepening, while financial deepening is endogenously chosen by agents given a policy and occurs in transition towards a distant steady state. This history-dependent view necessitates the use of simulation analysis based on a growth model. Our application is a specific episode: Thailand from 1976 to 1996. PMID:20806055

  2. Idaho National Laboratory Quarterly Performance Analysis - 1st Quarter FY2015

    SciTech Connect

    Mitchell, Lisbeth A.

    2015-03-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 73 reportable events (27 from the 1St Qtr FY-15 and 46 from the prior three reporting quarters), as well as 38 other issue reports (including nine not reportable events and Significant Category A and B conditions reported during the1st Qtr FY-15) identified at INL during the past 12 months.

  3. Quarterly coal report July--September 1995, February 1996

    SciTech Connect

    1996-02-16

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended. This report presents detailed quarterly data for July through September 1995 and aggregated quarterly historical data for 1987 through the second quarter of 1995. Appendix A displays, from 1987 on, detailed quarterly historical coal imports data, as specified in Section 202 of the Energy Policy and Conservation Amendments Act of 1985 (Public Law 99-58). Appendix B gives selected quarterly tables converted to metric tons.

  4. An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.

    PubMed

    Gruber, Tanja A; Larson Gedman, Amanda; Zhang, Jinghui; Koss, Cary S; Marada, Suresh; Ta, Huy Q; Chen, Shann-Ching; Su, Xiaoping; Ogden, Stacey K; Dang, Jinjun; Wu, Gang; Gupta, Vedant; Andersson, Anna K; Pounds, Stanley; Shi, Lei; Easton, John; Barbato, Michael I; Mulder, Heather L; Manne, Jayanthi; Wang, Jianmin; Rusch, Michael; Ranade, Swati; Ganti, Ramapriya; Parker, Matthew; Ma, Jing; Radtke, Ina; Ding, Li; Cazzaniga, Giovanni; Biondi, Andrea; Kornblau, Steven M; Ravandi, Farhad; Kantarjian, Hagop; Nimer, Stephen D; Döhner, Konstanze; Döhner, Hartmut; Ley, Timothy J; Ballerini, Paola; Shurtleff, Sheila; Tomizawa, Daisuke; Adachi, Souichi; Hayashi, Yasuhide; Tawa, Akio; Shih, Lee-Yung; Liang, Der-Cherng; Rubnitz, Jeffrey E; Pui, Ching-Hon; Mardis, Elaine R; Wilson, Richard K; Downing, James R

    2012-11-13

    To define the mutation spectrum in non-Down syndrome acute megakaryoblastic leukemia (non-DS-AMKL), we performed transcriptome sequencing on diagnostic blasts from 14 pediatric patients and validated our findings in a recurrency/validation cohort consisting of 34 pediatric and 28 adult AMKL samples. Our analysis identified a cryptic chromosome 16 inversion (inv(16)(p13.3q24.3)) in 27% of pediatric cases, which encodes a CBFA2T3-GLIS2 fusion protein. Expression of CBFA2T3-GLIS2 in Drosophila and murine hematopoietic cells induced bone morphogenic protein (BMP) signaling and resulted in a marked increase in the self-renewal capacity of hematopoietic progenitors. These data suggest that expression of CBFA2T3-GLIS2 directly contributes to leukemogenesis.

  5. Molecular and cytogenetic characterization of a recurrent unbalanced translocation (4;21) (p16.3;q22.1): Relevance to the Wolf-Hirschhorn and Down syndrome critical regions

    SciTech Connect

    Sebastio, G.; Perone, L.; Guzzetta, V.

    1996-05-17

    We report on an aneuploidy syndrome due to the unbalanced segregation of a familial translocation (4;21)(p16.3;q22.1) causing a partial 4p monosomy and a partial 21q trisomy. The three affected children presented with severe failure to thrive, short stature, microcephaly, profound hypotonia, and mental retardation. The face, very similar in the three children, is characterized by frontal bossing, upslanting of the palpebral fissures, short nose, and deep set ears, giving the overall appearance of the Down syndrome. The molecular study has defined the aneuploid segment on both 4p and 21q. Most of the Down syndrome critical region was found to be trisomic, while only part of the candidate Wolf-Hirschhorn syndrome critical region was deleted, suggesting that this region is not critical for the major malformations characteristic for WHS. 15 refs., 5 figs., 1 tab.

  6. Chromosomal location of two human genes encoding tetrahydrobiopterin-metabolizing enzymes: 6-pyruvoyl-tetrahydropterin synthase maps to 11q22. 3-q23. 3, and pterin-4[alpha]-carbinolamine dehydratase maps to 10q22

    SciTech Connect

    Thoeny, B.; Heizmann, C.W. ); Mattei, M.G. )

    1994-01-15

    Tetrahydrobiopterin (BH[sub 4]) is the redox cofactor for the aromatic amino acid hydroxylases such as phenylalanine hydroxylase. At least five enzymes are known to be involved in BH[sub 4] biosynthesis and regeneration. A deficiency in several of the BH[sub 4] metabolic enzymes causes variant types of hyperphenylalaninemias in man. Recently, the authors cloned and expressed the human cDNAs for two of the BH[sub 4] enzymes, the 6-pyruvoyl-tetrahydropterin synthase and the pterin-4[alpha]-carbinolamine dehydratase (gene symbols PTS and PCD/DCOH, respectively). In this report, they localized the two genes on the human chromsomes by in situ hybridization. The PTS gene was mapped to the chromosomal region 11q22.3-q23.3, and the PCD/DCOH gene was mapped to the 10q22 band of the genome. 18 refs., 2 figs.

  7. Short-term energy outlook. Quarterly projections, 2nd quarter 1994

    SciTech Connect

    Not Available

    1994-05-01

    The Energy Information Administration (EIA) prepares quarterly, short-term energy supply, demand, and price projections for publication in February, May, August, and November in the Short-Term Energy Outlook (Outlook). An annual supplement analyzes the performance of previous forecasts, compares recent cases with those of other forecasting services, and discusses current topics related to the short-term energy markets. The forecast period for this issue of the Outlook extends from the second quarter of 1994 through the fourth quarter of 1995. Values for the first quarter of 1994, however, are preliminary EIA estimates (for example, some monthly values for petroleum supply and disposition are derived in part from weekly data reported in the Weekly Petroleum Status Report) or are calculated from model simulations using the latest exogenous information available. The historical energy data, compiled into the second quarter 1994 version of the Short-Term Integrated Forecasting System (STIFS) database, are mostly EIA data regularly published in the Monthly Energy Review, Petroleum Supply Monthly, and other EIA publications. Minor discrepancies between the data in these publications and the historical data in this Outlook are due to independent rounding. The STIFS database is archived quarterly and is available from the National Technical Information Service. The cases are produced using the STIFS. The STIFS model is driven principally by three sets of assumptions or inputs: estimates of key macroeconomic variables, world oil price assumptions, and assumptions about the severity of weather. Macroeconomic estimates are produced by DRI/McGraw-Hill but are adjusted by EIA to reflect EIA assumptions about the world price of crude oil, energy product prices, and other assumptions which may affect the macroeconomic outlook. The EIA model is available on computer tape from the National Technical Information Service.

  8. Financial Information Project: Assessing the Financial Interests of College Students

    ERIC Educational Resources Information Center

    Masuo, Diane M.; Kutara, Pamela; Wall, Ronald; Cheang, Michael

    2007-01-01

    College graduates are entering the world of work with record levels of school-related debt despite being generally unprepared to face the financial challenges of life after college. Findings from a needs assessment survey of financial topics of interest to college students and staff/faculty and preferences for how the information should be…

  9. Understanding Financial Innovation: An Introduction to Derivative Financial Products.

    ERIC Educational Resources Information Center

    Robinson, J. N.

    1992-01-01

    Explains the use of forwards, futures, swaps, and options in international currency trading. Argues that pricing options are based on the same basic principles as pricing other financial instruments. Concludes that, although financial markets have developed several new products, hedging and speculation involve similar processes. (CFR)

  10. The Impact of Financial Literacy Education on Subsequent Financial Behavior

    ERIC Educational Resources Information Center

    Mandell, Lewis; Klein, Linda Schmid

    2009-01-01

    This study examined the differential impact on 79 high school students of a personal financial management course completed 1 to 4 years earlier. This study used a matched sample design based on a school system's records to identify students who had and had not taken a course in personal financial management. The findings indicated that those who…

  11. Density functional theory investigations of the homoleptic tris(dithiolene) complexes [M(dddt)(3)](-q) (q = 3, 2 ; M = Nd(3+) and U(3+/4+)) related to lanthanide(III)/actinide(III) differentiation.

    PubMed

    Meskaldji, Samir; Belkhiri, Lotfi; Arliguie, Thérèse; Fourmigué, Marc; Ephritikhine, Michel; Boucekkine, Abdou

    2010-04-01

    The structures of the homoleptic lanthanide and actinide tris(dithiolene) complexes [M(dddt)(3)](q-) (q = 3, M = Nd(3+) and q = 3 or 2, M = U(3+/4+)) have been investigated using relativistic Density Functional Theory (DFT) computations including spin-orbit corrections coupled with the COnductor-like Screening Model (COSMO) for a realistic solvation approach. The dithiolene ligands are known to be very efficient at stabilizing metal high oxidation states. The aim of the work is to explain the peculiar symmetric folding of the three Mdddt metallacycles in these complexes, some of them existing under a polymeric form, in relation with the Ln(III)/An(III) differentiation. In the [M(dddt)(3)(py)](q-) species, where an additional pyridine ligand is linked to the metal center, the Mdddt moieties appear to be almost planar. The study brings to light the occurrence of a M...C=C interaction explaining the Mdddt folding of the [U(dddt)(3)](q-) uranium species, the metal 5f electrons playing a driving role. No such interaction appears in the case of the Nd(III) complex, and the folding of the rather flexible dddt ligands in the polymeric structure of this species should be mainly due to steric effects. Moreover, the analysis of the normal modes of vibration shows that the U(III) complex [U(dddt)(3)](3-), which has not yet been isolated, is thermodynamically stable. It appears that the X-ray characterized U(IV) complex [U(dddt)(3)](2-) should be less stable than the calculated U(III) complex in a polar solvent.

  12. Array-based comparative genomic hybridization facilitates identification of breakpoints of a novel der(1)t(1;18)(p36.3;q23)dn in a child presenting with mental retardation.

    PubMed

    Lennon, P A; Cooper, M L; Curtis, M A; Lim, C; Ou, Z; Patel, A; Cheung, S W; Bacino, C A

    2006-06-01

    Monosomy of distal 1p36 represents the most common terminal deletion in humans and results in one of the most frequently diagnosed mental retardation syndromes. This deletion is considered a contiguous gene deletion syndrome, and has been shown to vary in deletion sizes that contribute to the spectrum of phenotypic anomalies seen in patients with monosomy 1p36. We report on an 8-year-old female with characteristics of the monosomy 1p36 syndrome who demonstrated a novel der(1)t(1;18)(p36.3;q23). Initial G-banded karyotype analysis revealed a deleted chromosome 1, with a breakpoint within 1p36.3. Subsequent FISH and array-based comparative genomic hybridization not only confirmed and partially characterized the deletion of chromosome 1p36.3, but also uncovered distal trisomy for 18q23. In this patient, the duplicated 18q23 is translocated onto the deleted 1p36.3 region, suggesting telomere capture. Molecular characterization of this novel der(1)t(1;18)(p36.3;q23), guided by our clinical array-comparative genomic hybridization, demonstrated a 3.2 Mb terminal deletion of chromosome 1p36.3 and a 200 kb duplication of 18q23 onto the deleted 1p36.3, presumably stabilizing the deleted chromosome 1. DNA sequence analysis around the breakpoints demonstrated no homology, and therefore this telomere capture of distal 18q is apparently the result of a non-homologous recombination. Partial trisomy for 18q23 has not been previously reported. The importance of mapping the breakpoints of all balanced and unbalanced translocations found in the clinical laboratory, when phenotypic abnormalities are found, is discussed.

  13. Idaho National Laboratory Quarterly Performance Analysis - 2nd Quarter FY2014

    SciTech Connect

    Lisbeth A. Mitchell

    2014-06-01

    This report is published quarterly by the Idaho National Laboratory (INL) Performance Assurance Organization. The Department of Energy Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of occurrence reports and other deficiency reports (including not reportable events) identified at INL from January 2014 through March 2014.

  14. Quarterly environmental radiological survey summary - second quarter 1997 100, 200, 300, and 600 areas

    SciTech Connect

    McKinney, S.M.; Marks, B.M.

    1997-07-22

    This report provides a summary of the radiological surveys performed in support of near-facility environmental monitoring at the Hanford Site. The Second Quarter 1997 survey results and the status of actions required are summarized below: All of the routine environmental radiological surveys scheduled during April, May, and June 1997, were performed as planned with the exception of UN-216-E-9. This site was not surveyed as stabilization activities were in progress. The sites scheduled for the Environmental Restorations Contractor (ERC) team were switched with those identified for the third quarter as there was a conflict with vegetation management activities.

  15. Idaho National Laboratory Quarterly Event Performance Analysis FY 2013 4th Quarter

    SciTech Connect

    Lisbeth A. Mitchell

    2013-11-01

    This report is published quarterly by the Idaho National Laboratory (INL) Performance Assurance Organization. The Department of Energy Occurrence Reporting and Processing System (ORPS) as prescribed in DOE Order 232.2 “Occurrence Reporting and Processing of Operations Information” requires a quarterly analysis of events, both reportable and not reportable for the previous twelve months. This report is the analysis of occurrence reports and deficiency reports (including not reportable events) identified at the Idaho National Laboratory (INL) during the period of October 2012 through September 2013.

  16. The Intersection of Financial Exploitation and Financial Capacity

    PubMed Central

    Lichtenberg, P.A.

    2016-01-01

    Research in the past decade has documented that financial exploitation of older adults has become a major problem and Psychology is only recently increasing its presence in efforts to reduce exploitation. During the same time period, Psychology has been a leader in setting best practices for the assessment of diminished capacity in older adults culminating in the 2008 ABA/APA joint publication on a handbook for psychologists. Assessment of financial decision making capacity is often the cornerstone assessment needed in cases of financial exploitation. This paper will examine the intersection of financial exploitation and decision making capacity; introduce a new conceptual model and new tools for both the investigation and prevention of financial exploitation. PMID:27159438

  17. Mixed Waste Management Facility groundwater monitoring report: Third quarter 1994

    SciTech Connect

    Not Available

    1994-12-01

    Currently, 125 wells monitor groundwater quality in the uppermost aquifer beneath the Mixed Waste Management Facility (MWMF) at the Savannah River Site. Samples from the wells are analyzed for selected heavy metals, herbicides/pesticides, indicator parameters, radionuclides, volatile organic compounds, and other constituents. As in previous quarters, tritium and trichloroethylene were the most widespread elevated constituents during third quarter 1994. Sixty-four (51%) of the 125 monitoring wells contained elevated tritium activities. Trichloroethylene concentrations exceeded the final PDWS in 22 (18%) wells. Chloroethene, 1,1-dichloroethylene, and tetrachloroethylene, elevated in one or more wells during third quarter 1994, also occurred in elevated levels during second quarter 1994. These constituents generally were elevated in the same wells during both quarters. Gross alpha, which was elevated in only one well during second quarter 1994, was elevated again during third quarter. Mercury, which was elevated during first quarter 1994, was elevated again in one well. Dichloromethane was elevated in two wells for the first time in several quarters.

  18. Photographic copy of floor plans for Bachelor Officers' Quarters (Tl) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of floor plans for Bachelor Officers' Quarters (T-l) known as the "Desert Rat Hotel" in the early days of the Muroc Flight Test Base (North Base). The plans show the layout of quarters, lavatories, mess as well as, the cooling system installation. Contract W-509-Eng 2937, Military Construction; Muroc Bombing Range, Muroc Lake, Calif; Materiel Test Site, Officers Quarters, Evaporative Coolers, Sheet 5 of 11, May 1942. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, Bachelor Officers' Quarters T-1, Second & C Streets, Boron, Kern County, CA

  19. Natural gas imports and exports: First quarter report 1995

    SciTech Connect

    1995-07-01

    The Office of Fuels Programs prepares quarterly reports summarizing the data provided by companies authorized to import or export natural gas. Companies are required, as a condition of their authorizations, to file quarterly reports with the OFP. This quarter`s focus is market penetration of gas imports into New England. Attachments show the following: % takes to maximum firm contract levels and weighted average per unit price for the long-term importers, volumes and prices of gas purchased by long-term importers and exporters, volumes and prices for gas imported on short-term or spot market basis, and gas exported short-term to Canada and Mexico.

  20. Linking XBRL Financial Data

    NASA Astrophysics Data System (ADS)

    García, Roberto; Gil, Rosa

    One of the main ways of populating the Web of Data is by translating existing data sources. One interesting candidate for this approach is data based on the eXtensible Business Reporting Language (XBRL), a standard for business and financial reporting. Many institutions are making available or requiring data in this format, e.g. the U.S. Securities and Exchange Commission (SEC) through the EDGAR program. However, XBRL data is loosely interconnected and it is difficult to mix and query it. Our contribution is a translation from XBRL filings to Semantic Web technologies, which we have applied to more than 1000 filings obtaining more than 2 million triples. The resulting semantic data is easier to integrate and cross query. Moreover, it can be interconnected with the rest of the Web of Data in order to extract its full potential.

  1. 40 CFR 35.6670 - Financial reports.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... recipient must comply with the requirements regarding financial reporting described in 40 CFR 31.41. (b) Financial Status Report—(1) Content. (i) The Financial Status Report (SF-269) must include financial information by site, activity, and operable unit, as applicable. (ii) A final Financial Status Report...

  2. 40 CFR 35.6670 - Financial reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... recipient must comply with the requirements regarding financial reporting described in 40 CFR 31.41. (b) Financial Status Report—(1) Content. (i) The Financial Status Report (SF-269) must include financial information by site, activity, and operable unit, as applicable. (ii) A final Financial Status Report...

  3. Financial Knowledge and Best Practice Behavior

    ERIC Educational Resources Information Center

    Robb, Cliff A.; Woodyard, Ann S.

    2011-01-01

    The current research examines the relationship between personal financial knowledge (both objective and subjective), financial satisfaction, and selected demographic variables in terms of best practice financial behavior. Data are taken from the Financial Industry Regulatory Authority's (FINRA) National Financial Capability Study, a nationally…

  4. Financial Scandals and Student Loans

    ERIC Educational Resources Information Center

    Eisenberg, Meyer; Franke, Ann H.

    2007-01-01

    The investigations of student-loan programs around the country echo previous scandals in the financial world involving stock offerings and mutual funds. The relationships between lenders and financial-aid officers seem to raise the same questions about impropriety, conflict of interest, and possible fraud. Indeed, lessons from Wall Street can…

  5. Manual for Student Financial Aids.

    ERIC Educational Resources Information Center

    MacDonald, Douglas S.

    This manual was designed to provide structural guidelines for financial aid program operations and administration at the Community College of Baltimore. Topics discussed include: the philosophy of student aid at an open door college; the objectives of the student financial aid office; staff development and administrative improvement; organization,…

  6. Teaching OOP with Financial Literacy

    ERIC Educational Resources Information Center

    Zhu, Hongwei

    2011-01-01

    Students lose interest in learning programming when the materials are not related to their lives. A challenge facing most students is that they lack the financial literacy necessary to manage their debts. An approach is developed to integrate financial literacy into an object-oriented programming (OOP) course. The approach is effective in…

  7. Financial Resources for Disabled Individuals.

    ERIC Educational Resources Information Center

    Institute for Information Studies, Falls Church, VA.

    The guide is intended to provide a practical source of information on financial resources for disabled individuals. Following an introductory chapter is a chapter discussing some fundamental principles useful in increasing the likelihood that a benefit will be awarded. Subsequent chapters contain information on financial assistance programs in…

  8. Legislative Mandates and Financial Reporting.

    ERIC Educational Resources Information Center

    Bock, Almon C., II

    1983-01-01

    Asserts the importance of each school business official's responsibility to accurately report the school's financial situation to the state legislature. Uses Minnesota's 33 area vocational technical institutes to illustrate the application of statewide uniform financial accounting and reporting standards to Minnesota public school districts. (JBM)

  9. Certification of Financial Aid Administrators

    ERIC Educational Resources Information Center

    Peterson, Stacey A.

    2011-01-01

    The certification of financial aid administrators has been debated for over 37 years. A job satisfaction survey conducted by the National Association of Student Financial Aid Administrators (NASFAA, 2008a) revealed that college and university administrators' perceptions of the efficiency, effectiveness, and quality of the services provided by the…

  10. 75 FR 22680 - Financial Management Service; Proposed Collection of Information: Annual Financial Statement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... Fiscal Service Financial Management Service; Proposed Collection of Information: Annual Financial.... ADDRESSES: Direct all written comments to Financial Management Service, Records and Information Management... Financial Management Service solicits comments on the collection of information described below:...

  11. Quarterly environmental radiological survey summary. Fourth quarter, 1995 100, 200, 300, and 600 Areas

    SciTech Connect

    McKinney, S.M.; Markes, B.M.

    1996-01-01

    This report provides a summary of the radiological surveys performed in support of the operational environmental monitoring program at the Hanford Site. The Fourth Quarter 1995 survey results and the status of actions required from current and past reports are described.

  12. Electric and hybrid vehicle project. Quarterly report of private-sector operations, first quarter 1982

    SciTech Connect

    1982-06-01

    As of January 1, 1982 sixteen private-sector site operators at 30 sites in the US were involved in electric and hybrid electric-powered vehicle demonstration programs. Data for 1981 and the first quarter of 1982 are presented on vehicle selection, miles accumulated, energy usage, maintenance requirements, reliability and operating performance for demonstration vehicles at each site. (LCL)

  13. How To Assess and Enhance Financial Health.

    ERIC Educational Resources Information Center

    Hudack, Lawrence R.; Orsini, Larry L.; Snow, Brenda M.

    2003-01-01

    Describes how Saint Bonaventure University is using a ratio analysis based on a composite financial index to transform itself from an institution with adequate financial resources into a financially vibrant institution. (EV)

  14. Anaerobic treatment of gasifier effluents. Quarterly report

    SciTech Connect

    Cross, W.H.; Chian, E.S.K.; Pohland, F.G.; Giabbai, M.; Harper, S.R.; Kharkar, S.; Cheng, S.S.; Shuey, P.S.

    1982-01-01

    This report summarizes the work performed during the quarter ending December 30, 1981. The major efforts have been directed toward the continued acclimation of two anaerobic treatment systems, start up of a third anaerobic treatment system, GC/MS characterization of the coal gasification wastewater, data acquisition for determination of distribution coefficients for the extraction of phenol from the wastewater using MIBK, and preliminary design of a solvent extraction system for wastewater pretreatment. The progress of these efforts are depicted in the Gannt Chart, along with project expenditures for the above contract, and are presented in detail in the following sections.

  15. Performance indicators, third quarter CY-1991

    SciTech Connect

    Not Available

    1992-01-01

    Secretary of Energy Notice (SEN-29-91) directed that a Department- wide uniform system of Performance Indicators (PI's) for trending and analyzing operational data to help assess and support progress in improving performance and in strengthening line management control of operations relating to environmental safety, and health activities'' be developed. This Performance Indicator Report represents a compilation of data for the third quarter of calendar year 1991 for the following Lawrence Berkeley Laboratory (LBL) facilities: (1) Bevalac, (2) 88-Inch Cyclotron, (3) Materials Sciences Division.

  16. Performance indicators, third quarter CY-1991

    SciTech Connect

    Not Available

    1992-01-01

    Secretary of Energy Notice (SEN-29-91) directed that a Department- wide ``uniform system of Performance Indicators (PI`s) for trending and analyzing operational data to help assess and support progress in improving performance and in strengthening line management control of operations relating to environmental safety, and health activities`` be developed. This Performance Indicator Report represents a compilation of data for the third quarter of calendar year 1991 for the following Lawrence Berkeley Laboratory (LBL) facilities: (1) Bevalac, (2) 88-Inch Cyclotron, (3) Materials Sciences Division.

  17. Quail Egg compared to a quarter

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Quail eggs are small (shown here with a quarter for scale) and develop quickly, making them ideal for space experiments. The Avian Development Facility (ADF) supports 36 eggs in two carousels (below), one of which rotates to provide a 1-g control for comparing to eggs grown in microgravity. The ADF originated in NASA's Shuttle Student Involvement program in the 1980s and was developed under the NASA Small Business Irnovation Research program. In late 2001, the ADF made its first flight and carried eggs used in two investigations, Development and function of the inner-ear balance system in normal and altered gravity environments, and Skeletal development in embryonic quail.

  18. Quarterly coal report, July--September 1993

    SciTech Connect

    Not Available

    1994-02-18

    The Quarterly Coal Report (QCR) provides comprehensive information about US coal production, distribution, exports, imports, receipts, prices, consumption, and stocks to a wide audience, including Congress, Federal and State agencies, the coal industry, and the general public. Coke production, consumption, distribution, imports, and exports data are also provided. The data presented in the QCR are collected and published by the Energy Information Administration (EIA) to fulfill data collection and dissemination responsibilities as specified in the Federal Energy Administration Act of 1974 (Public Law 93-275), as amended.

  19. Biomass power for rural development. Quarterly report, April 3--July 1, 1998

    SciTech Connect

    Cooper, J.T.

    1998-10-01

    In this quarter a large amount of time was spent doing project planning and budget preparation for the fiscal years 1998 and 1999. Many issues of long-term strategic planning and budgeting depend on the availability of Federal support, including financial, technical and political. It has become increasingly obvious that several significant barriers must be overcome in order to reach the final goal of commercial replication of the technology. Technical barriers include the designing of a cost effective harvest, storage, transport, process and conversion system. While farmers in this region have many decades of experience in harvest, storage and transport of grass, switchgrass presents new challenges due to the harvest requirements and the switchgrass yield potential. The author has identified two locations in the United States that have similar material handling situations, one site in Minnesota the other in Oregon. He has visited the Minnesota site in order to learn from their experience and they may visit the Oregon site in the future. The processing technology remains in a stage of development. As he grows closer to the time for a test co-fire he is beginning to include additional test objectives which individually seem minor, but when taken together provide drivers which impact overall machinery requirement decisions. The next quarter will provide additional levels of detail. This report describes progress in switchgrass conversion development, production activities, environmental analysis planning, and information and education activities.

  20. 52. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. Photocopy of copy of original Officers' Duplex Quarters drawing by Copeland, 7 April 1932 (Original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University). Heating - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  1. 51. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Photocopy of copy of original Officers' Duplex Quarters drawing by B.S. Elliott, 7 April 1932 (original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University). Plumbing - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  2. ROYAL PALMLINED WALK TO FACILITY 1041 (QUARTERS J) WITH FACILITY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ROYAL PALM-LINED WALK TO FACILITY 1041 (QUARTERS J) WITH FACILITY 1040 (QUARTERS 1) TO LEFT. TAKEN AT CORNER OF HALE ALII AVENUE AND EIGHTH STREET. VIEW FACING EAST. - U.S. Naval Base, Pearl Harbor, Naval Housing Area Hale Alii, Hale Alii Avenue, Eighth Street, & Avenue D, Pearl City, Honolulu County, HI

  3. The Savannah River Site's Groundwater Monitoring Program, third quarter 1991

    SciTech Connect

    Not Available

    1992-02-17

    The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site's (SRS) Groundwater Monitoring Program. During third quarter 1991, EPD/EMS conducted extensive sampling of monitoring wells. Analytical results from third quarter 1991 are listed in this report.

  4. 32 CFR 584.7 - Basic allowance for quarters.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Basic allowance for quarters. 584.7 Section 584..., CHILD CUSTODY, AND PATERNITY § 584.7 Basic allowance for quarters. (a) Eligibility. (1) Soldiers entitled to basic pay, who have family members, are entitled to BAQ at the rates prescribed for...

  5. 32 CFR 584.7 - Basic allowance for quarters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Basic allowance for quarters. 584.7 Section 584.7... CUSTODY, AND PATERNITY § 584.7 Basic allowance for quarters. (a) Eligibility. (1) Soldiers entitled to basic pay, who have family members, are entitled to BAQ at the rates prescribed for soldiers...

  6. Residential Group Care Quarterly. Volume 7, Number 1, Summer 2006

    ERIC Educational Resources Information Center

    Michael, Jennifer, Ed.

    2006-01-01

    "Residential Group Care Quarterly" is published four times a year by the Child Welfare League of America (CWLA). This issue of "Residential Group Care Quarterly" contains the following articles: (1) Building Bridges between Service Delivery Providers, Families, and Youth (Lloyd Bullard); (2) The Promise of Professionalism Arrives in Practice:…

  7. 48. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    48. Photocopy of copy of original Officers' Duplex Quarters drawing by Turner, 7 April 1932 (original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University). Attic and roof, basement, first floor, and second floor plans - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  8. 50. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. Photocopy of copy of original Officers' Duplex Quarters drawing by Turner, 7 April 1932 (original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University. Detail of front entrance and of gable dormer - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  9. 49. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Photocopy of copy of original Officers' Duplex Quarters drawing by Turner, 7 April 1932 (original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University). Front, rear, and side elevations, and cross-section - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  10. 257. GENERAL VIEW OF SENIOR OFFICER'S QUARTERS, 194041. GEORGE A. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    257. GENERAL VIEW OF SENIOR OFFICER'S QUARTERS, 1940-41. GEORGE A. FULLER AND CO., DESIGNERS OF REWORKING OF THESE C. 1939 SUMMER COTTAGES INTO NEO-COLONIAL RESIDENCES. VIEW NORTHEAST DOWN GLENN CURTIS DRIVE SHOWING, FROM LEFT TO RIGHT: QUARTER P, O, N, C, A, S, R, AND Q. - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

  11. 17 CFR 31.26 - Quarterly reporting requirement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... LEVERAGE TRANSACTIONS § 31.26 Quarterly reporting requirement. Each leverage transaction merchant must file... month following the quarter covered by the report. The report must list all leverage contracts which were either repurchased, resold, liquidated or settled by delivery by or to the leverage...

  12. Residential Group Care Quarterly. Volume 7, Number 2, Fall 2006

    ERIC Educational Resources Information Center

    Ruby, Kathy, Ed.

    2006-01-01

    "Residential Group Care Quarterly" is published four times a year by the Child Welfare League of America (CWLA). This issue of "Residential Group Care Quarterly" contains the following articles: (1) Whatever Happened to Sound Clinical Reasoning? (Elizabeth Kohlstaedt); (2) Minorities as Majority Disproportionality in Child Welfare and Juvenile…

  13. Apprentices & Trainees: Early Trend Estimates. March Quarter 2010

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2010

    2010-01-01

    This new publication presents early estimates of apprentice and trainee commencements in the March quarter 2010. Indicative information about the current quarter is presented here in response to the demand for more timely data. The most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The…

  14. Apprentices & Trainees: Early Trend Estimates. December Quarter, 2014

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2015

    2015-01-01

    This publication presents early estimates of apprentice and trainee commencements for the December quarter 2014. Indicative information about this quarter is presented here; the most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The early trend estimates are derived from the National…

  15. 10 CFR 34.69 - Records of quarterly inventory.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Records of quarterly inventory. 34.69 Section 34.69 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Recordkeeping Requirements § 34.69 Records of quarterly inventory....

  16. 10 CFR 34.69 - Records of quarterly inventory.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Records of quarterly inventory. 34.69 Section 34.69 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Recordkeeping Requirements § 34.69 Records of quarterly inventory....

  17. Apprentices and Trainees: Early Trend Estimates. December Quarter 2010

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2011

    2011-01-01

    This publication presents early estimates of apprentice and trainee commencements for the December quarter 2010. Indicative information about this quarter is presented here; the most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The early trend estimates are derived from the National…

  18. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... (a) Countries for which quarterly rate is certified. For the currency of each of the following foreign countries, there will be published in the Customs Bulletin, for the quarter beginning January 1..., Singapore, Spain, Sri Lanka (Ceylon), Sweden, Switzerland, Thailand, United Kingdom, Venezuela. (b)...

  19. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... (a) Countries for which quarterly rate is certified. For the currency of each of the following foreign countries, there will be published in the Customs Bulletin, for the quarter beginning January 1..., Singapore, Spain, Sri Lanka (Ceylon), Sweden, Switzerland, Thailand, United Kingdom, Venezuela. (b)...

  20. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... (a) Countries for which quarterly rate is certified. For the currency of each of the following foreign countries, there will be published in the Customs Bulletin, for the quarter beginning January 1..., Singapore, Spain, Sri Lanka (Ceylon), Sweden, Switzerland, Thailand, United Kingdom, Venezuela. (b)...

  1. Apprentices and Trainees: Early Trend Estimates. June Quarter 2010

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2010

    2010-01-01

    This publication presents early estimates of apprentice and trainee commencements for the June quarter 2010. Indicative information about this quarter is presented here; the most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The early trend estimates are derived from the National…

  2. Apprentices & Trainees: Early Trend Estimates. December Quarter 2011

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2012

    2012-01-01

    This publication presents early estimates of apprentice and trainee commencements for the December quarter 2011. Indicative information about this quarter is presented here; the most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The early trend estimates are derived from the National…

  3. 76 FR 16037 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the second quarter 2011 Rail Cost Adjustment Factor (RCAF) and cost index filed by the Association of...

  4. 77 FR 37958 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the third quarter 2012 rail cost adjustment factor (RCAF) and cost index filed by the Association of...

  5. 77 FR 76169 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the AAR's proposed rebasing calculations and the rebased first quarter 2013 rail cost adjustment factor (RCAF)...

  6. 75 FR 58019 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2010 Rail Cost Adjustment Factor (RCAF) and cost index filed by the Association of...

  7. 78 FR 17764 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the second quarter 2013 Rail Cost Adjustment Factor (RCAF) and cost index filed by the Association of...

  8. 76 FR 80448 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the first quarter 2012 rail cost adjustment factor (RCAF) and cost index filed by the Association of American Railroads....

  9. 76 FR 37191 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the third quarter 2011 Rail Cost Adjustment Factor (RCAF) and cost index filed by the Association of...

  10. 78 FR 59093 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2013 rail cost adjustment factor (RCAF) and cost index filed by the Association of...

  11. 75 FR 35877 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... TRANSPORTATION Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the third quarter 2010 rail cost adjustment factor (RCAF) and cost index filed by the Association of...

  12. 78 FR 37660 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-21

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board approves the third quarter 2013 Rail Cost Adjustment Factor (RCAF) and cost index filed by the Association of American...

  13. 76 FR 59483 - Quarterly Rail Cost Adjustment Factor

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... Surface Transportation Board Quarterly Rail Cost Adjustment Factor AGENCY: Surface Transportation Board, DOT. ACTION: Approval of rail cost adjustment factor. SUMMARY: The Board has approved the fourth quarter 2011 Rail Cost Adjustment Factor (RCAF) and cost index filed by the Association of...

  14. 270. OFFICERS' QUARTERS (FORMER SUMMER COTTAGES) AT DOG PATCH BEACH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    270. OFFICERS' QUARTERS (FORMER SUMMER COTTAGES) AT DOG PATCH BEACH, C. 1939. VIEW NORTH DOWN GREENWICH ROAD TOWARD FORMER SUMMER COTTAGES, CONVERTED TO OFFICER'S QUARTERS, OVER-LOOKING DOG PATCH BEACH. - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

  15. Apprentices & Trainees: Early Trend Estimates. December Quarter, 2012

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2013

    2013-01-01

    This publication presents early estimates of apprentice and trainee commencements for the December quarter 2012. Indicative information about this quarter is presented here; the most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The early trend estimates are derived from the National…

  16. Apprentices & Trainees: Early Trend Estimates. March Quarter, 2012

    ERIC Educational Resources Information Center

    National Centre for Vocational Education Research (NCVER), 2012

    2012-01-01

    This publication presents early estimates of apprentice and trainee commencements for the March quarter 2012. Indicative information about this quarter is presented here; the most recent figures are estimated, taking into account reporting lags that occur at the time of data collection. The early trend estimates are derived from the National…

  17. 41 CFR 114-51.100 - Departmental Quarters Handbook.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Handbook. 114-51.100 Section 114-51.100 Public Contracts and Property Management Federal Property...-General § 114-51.100 Departmental Quarters Handbook. The Office of Acquisition and Property Management (PAM) has prepared the Departmental Quarters Handbook (DQH), 400 DM, which provides detailed...

  18. 41 CFR 114-51.100 - Departmental Quarters Handbook.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Handbook. 114-51.100 Section 114-51.100 Public Contracts and Property Management Federal Property...-General § 114-51.100 Departmental Quarters Handbook. The Office of Acquisition and Property Management (PAM) has prepared the Departmental Quarters Handbook (DQH), 400 DM, which provides detailed...

  19. SLAVE QUARTERS (RESTORED). This is the north building, one of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SLAVE QUARTERS (RESTORED). This is the north building, one of the two identical buildings in the plantation. Each building has a 2-room plan. - Hopsewee Plantation, Slave Quarters, U.S. Routes 17 & 701, Santee River, North, Georgetown, Georgetown County, SC

  20. Neural antecedents of financial decisions.

    PubMed

    Knutson, Brian; Bossaerts, Peter

    2007-08-01

    To explain investing decisions, financial theorists invoke two opposing metrics: expected reward and risk. Recent advances in the spatial and temporal resolution of brain imaging techniques enable investigators to visualize changes in neural activation before financial decisions. Research using these methods indicates that although the ventral striatum plays a role in representation of expected reward, the insula may play a more prominent role in the representation of expected risk. Accumulating evidence also suggests that antecedent neural activation in these regions can be used to predict upcoming financial decisions. These findings have implications for predicting choices and for building a physiologically constrained theory of decision-making.

  1. Quarterly Technical Progress Report June 2015

    SciTech Connect

    Buchholz, Bruce A.

    2015-06-08

    The project has two main goals: 1) Identify the types of adducts naphthalene (NA) forms with DNA and 2) determine whether adduct formation correlates with site selective tumor formation in defined subcompartments of the respiratory tract (respiratory and olfactory nasal epithelium and airways of mice, rats and rhesus monkeys). Five tasks are associated with the completion of the goals. Task 1: Contracting and Animal Use Approvals. IACUC and ACURO approvals are complete, The subcontract with UC Davis (UCD) was executed in December 2014. Task 2: Perform In Vitro Study for Goal 1. Rat samples exposed and in freezer while adduct standards are being made. Mouse samples need to be exposed in next quarter. Task 3: Perform In Vitro Study for Goal 2. Mouse ex vivo samples completed. Rat and monkey samples need to be completed in the next quarter. Task 4: Sample Preparation and Analysis. Mouse Goal 2 samples completed. Other samples remain to be done. Task 5: Data Interpretation and Reporting. Need rat data to write paper on adduct formation.

  2. Review of a Proposed Quarterly Coal Publication

    SciTech Connect

    Not Available

    1981-01-01

    This Review of a Proposed Quartery Coal Publication contains findings and recommendations regarding the content of a new summary Energy Information Administration (EIA) coal and coke publication entitled The Quarterly Coal Review (QCR). It is divided into five sections: results of interviews with selected EIA data users; identification of major functions of the coal and coke industries; analysis of coal and coke data collection activities; evaluation of issues conerning data presentation including recommendations for the content of the proposed QCR; and comparison of the proposed QCR with other EIA publications. Major findings and recommendations are as follows: (1) User interviews indicate a definite need for a compehensive publication that would support analyses and examine economic, supply and demand trends in the coal industry; (2) the organization of the publication should reflect the natural order of activities of the coal and coke industries. Based on an analysis of the industries, these functions are: production, stocks, imports, exports, distribution, and consumption; (3) current EIA coal and coke surveys collect sufficient data to provide a summary of the coal and coke industries on a quarterly basis; (4) coal and coke data should be presented separately. Coke data could be presented as an appendix; (5) three geographic aggregations are recommended in the QCR. These are: US total, coal producing districts, and state; (6) coal consumption data should be consolidated into four major consumer categories: electric utilities, coke plants, other industrial, and residential commercial; (7) several EIA publications could be eliminated by the proposed QCR.

  3. Adolescents' financial literacy: the role of financial socialization agents, financial experiences, and money attitudes in shaping financial literacy among South Korean youth.

    PubMed

    Sohn, Sang-Hee; Joo, So-Hyun; Grable, John E; Lee, Seonglim; Kim, Minjeung

    2012-08-01

    The purpose of this study was to test the relationships between financial socialization agents, financial experiences, money attitudes, demographic characteristics, and the financial literacy of Korean adolescents. Using the 2006 Korean National Financial Literacy Test Survey for Adolescents (N = 1185), a series of regression analyses were performed to determine the factors related to financial literacy. It was found that those who chose media as their primary financial socialization agent, and those who had a bank account, exhibited higher levels of financial literacy. Among the sample, those who saw money as good or as a reward for efforts tended to report higher levels of financial literacy, while those perceiving money in terms of avoidance or achievement had lower levels of financial literacy. Students with mid-range monthly allowances showed higher levels of financial literacy compared to the highest allowance group. Implications for financial educators, policy makers, and researchers are provided.

  4. Fractal properties of financial markets

    NASA Astrophysics Data System (ADS)

    Budinski-Petković, Lj.; Lončarević, I.; Jakšić, Z. M.; Vrhovac, S. B.

    2014-09-01

    We present an analysis of the USA stock market using a simple fractal function. Financial bubbles preceding the 1987, 2000 and 2007 crashes are investigated using the Besicovitch-Ursell fractal function. Fits show a good agreement with the S&P 500 data when a complete financial growth is considered, starting at the threshold of the abrupt growth and ending at the peak. Moving the final time of the fitting interval towards earlier dates causes growing discrepancy between two curves. On the basis of a detailed analysis of the financial index behavior we propose a method for identifying the stage of the current financial growth and estimating the time in which the index value is going to reach the maximum.

  5. Financial Implications of Curriculum Range.

    ERIC Educational Resources Information Center

    Harrold, Ross

    1978-01-01

    This article attempts to clarify the interdependent nature of curricular and financial aspects of school organization, then to provide a conceptual tool to help administrators consider both aspects concurrently. (Author)

  6. Reading and understanding financial statements.

    PubMed

    White, Joseph P

    2005-01-01

    Feeling comfortable reading and understanding financial statements is critical to the success of healthcare executives and physicians involved in management. Businesses use three primary financial statements: a balance sheet represents the equation, Assets = Liabilities + Equity; an income statement represents the equation, Revenues - Expenses = Net Income; a statement of cash flows reports all sources and uses of cash during the represented period. The balance sheet expresses financial indicators at one particular moment in time, whereas the income statement and the statement of cash flows show activity that occurred over a stretch of time. Additional information is disclosed in attached footnotes and other supplementary materials. There are two ways to prepare financial statements. Cash-basis accounting recognizes revenue when it is received and expenses when they are paid. Accrual-basis accounting recognizes revenue when it is earned and expenses when they are incurred. Although cash-basis is acceptable, periodically using the accrual method reveals important information about receivables and liabilities that could otherwise remain hidden. Become more engaged with your financial statements by spending time reading them, tracking key performance indicators, and asking accountants and financial advisors questions. This will help you better understand your business and build a successful future. PMID:16095076

  7. A balanced de novo inv(7)(p14.3q22.3) disrupting PDE1C and ATXN7L1 in a 14-year old developmentally delayed boy.

    PubMed

    Gamage, Thilini H; Misceo, Doriana; Fannemel, Madeleine; Frengen, Eirik

    2013-07-01

    We report a 14 year old male patient ascertained for developmental delay, carrying a de novo pericentric inversion on chr(7)(p14.3q22.3). Sequencing revealed that the breakpoints overlap a LTR sequence on 7q22.3 and a LINE on 7p14.3. A TTTAAA motif was found in proximity of the breakpoints on both arms. In addition the sequencing detected several small micro-rearrangements, deletion, duplication, insertion, at the breakpoints. No significant sequence identity exists between the 7p14.3 and 7q22.3 breakpoints. These features at the breakpoint junctions suggest that the inversion was triggered by the TTTAAA motif, LTR and LINE and healed by a Non Homologous End Joining (NHEJ) mechanism. The genes ATXN7L1 and PDE1C are disrupted by the inversion. PDE1C is responsible for the hydrolysis of the second messenger molecules cAMP and cGMP and is highly expressed in the human heart and certain brain regions. In mice, Pde1c is expressed in migrating neuronal cells within the central nervous system during early embryo development. Although neuronal migration disorder was not seen in our patient, this is the first patient described with haploinsufficiency of PDE1C possibly causing developmental delay.

  8. A novel interstitial deletion of 2q22.3 q23.3 in a patient with dysmorphic features, epilepsy, aganglionosis, pure red cell aplasia, and skeletal malformations.

    PubMed

    Bravo-Oro, Antonio; Lurie, Iosif W; Elizondo-Cárdenas, Gabriela; Peña-Zepeda, Claudia; Salazar-Martínez, Abel; Correa-González, Cecilia; Castrillo, José Luis; Avila, Silvia; Esmer, Carmen

    2015-08-01

    Many chromosomal deletions encompassing the 2q23.1 region have been described ranging from small deletions of 38 kb up to >19 Mb. Most phenotypic features of the 2q23.1 deletion syndrome are due to a MBD5 gene loss independent of the size of the deletion. Here, we describe a male patient harboring a novel interstitial deletion encompassing the 2q22.3 q23.3 chromosomal region. Array-CGH revealed a 7.1 Mb deletion causing haploinsufficiency of several genes including MBD5, ACVR2, KIF5C, and EPC2. This patient presents with additional findings to those already described in individuals who have deletions of MBD5 including toes absence of halluces, pure red cell aplasia, and intestinal aganglionosis. Interestingly, in the deleted region there are previously identified regulatory sequences which are located upstream to ZEB2, which is associated with Hirschsprung disease (HSCR). Several genes have been associated with pure red cell aplasia, but to our knowledge, this is the first time that 2q deletion is associated with this phenotype. These additional findings should be added to the list of manifestations associated with 2q deletion, and provide support for the hypothesis that this individual has a true contiguous gene deletion syndrome. PMID:25988649

  9. A Novel Four-Way Complex Variant Translocation Involving Chromosome 46,XY,t(4;9;19;22)(q25:q34;p13.3;q11.2) in a Chronic Myeloid Leukemia Patient.

    PubMed

    Asif, Muhammad; Jamal, Mohammad Sarwar; Khan, Abdul Rehman; Naseer, Muhammad Imran; Hussain, Abrar; Choudhry, Hani; Malik, Arif; Khan, Shahida Aziz; Mahmoud, Maged Mostafa; Ali, Ashraf; Iram, Saima; Kamran, Kashif; Iqbal, Asim; Abduljaleel, Zainularifeen; Pushparaj, Peter Natesan; Rasool, Mahmood

    2016-01-01

    Philadelphia (Ph) chromosome (9;22)(q34;q11) is well established in more than 90% of chronic myeloid leukemia (CML) patients, and the remaining 5-8% of CML patients show variant and complex translocations, with the involvement of third, fourth, or fifth chromosome other than 9;22. However, in very rare cases, the fourth chromosome is involved. Here, we found a novel case of four-way Ph+ chromosome translocation involving 46,XY,t(4;9;19;22)(q25:q34;p13.3;q11.2) with CML in the chronic phase. Complete blood cell count of the CML patient was carried out to obtain total leukocytes count, hemoglobin, and platelets. Fluorescence in situ hybridization technique was used for the identification of BCR-ABL fusion gene, and cytogenetic test for the confirmation of Ph (9;22)(q34;q11) and the mechanism of variant translocation in the bone marrow. The patient is successfully treated with a dose of 400 mg/day imatinib mesylate (Gleevec). We observed a significant decrease in white blood cell count of 11.7 × 10(9)/L after 48-month follow-up. Patient started feeling better generally. There was a reduction in the swelling of the body, fatigue, and anxiety. PMID:27303656

  10. A Novel Four-Way Complex Variant Translocation Involving Chromosome 46,XY,t(4;9;19;22)(q25:q34;p13.3;q11.2) in a Chronic Myeloid Leukemia Patient

    PubMed Central

    Asif, Muhammad; Jamal, Mohammad Sarwar; Khan, Abdul Rehman; Naseer, Muhammad Imran; Hussain, Abrar; Choudhry, Hani; Malik, Arif; Khan, Shahida Aziz; Mahmoud, Maged Mostafa; Ali, Ashraf; Iram, Saima; Kamran, Kashif; Iqbal, Asim; Abduljaleel, Zainularifeen; Pushparaj, Peter Natesan; Rasool, Mahmood

    2016-01-01

    Philadelphia (Ph) chromosome (9;22)(q34;q11) is well established in more than 90% of chronic myeloid leukemia (CML) patients, and the remaining 5–8% of CML patients show variant and complex translocations, with the involvement of third, fourth, or fifth chromosome other than 9;22. However, in very rare cases, the fourth chromosome is involved. Here, we found a novel case of four-way Ph+ chromosome translocation involving 46,XY,t(4;9;19;22)(q25:q34;p13.3;q11.2) with CML in the chronic phase. Complete blood cell count of the CML patient was carried out to obtain total leukocytes count, hemoglobin, and platelets. Fluorescence in situ hybridization technique was used for the identification of BCR–ABL fusion gene, and cytogenetic test for the confirmation of Ph (9;22)(q34;q11) and the mechanism of variant translocation in the bone marrow. The patient is successfully treated with a dose of 400 mg/day imatinib mesylate (Gleevec). We observed a significant decrease in white blood cell count of 11.7 × 109/L after 48-month follow-up. Patient started feeling better generally. There was a reduction in the swelling of the body, fatigue, and anxiety. PMID:27303656

  11. A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1.

    PubMed

    Shimizu, Atsushi; Asakawa, Shuichi; Sasaki, Takashi; Yamazaki, Satoru; Yamagata, Hidehisa; Kudoh, Jun; Minoshima, Shinsei; Kondo, Ikuko; Shimizu, Nobuyoshi

    2003-09-12

    We identified a novel giant gene encoding a transmembrane protein with CUB and sushi multiple domains on the human chromosome 8q23.3-q24.1 in which benign adult familial myoclonic epilepsy type 1 (BAFME1/FAME, OMIM:601068) has been mapped. This giant gene consists of 73 exons and spans over 1.2Mb on the genomic DNA region. It showed significant homology to two genes, CSMD1 gene on 8p23 and CSMD2 gene on 1p34, at reduced amino acid sequence level and hence we designated as CSMD3. The CSMD3 gene was expressed mainly in adult and fetal brains. We performed mutation analysis on the CSMD3 gene for seven patients with BAFME1/FAME, but no mutation was found in the coding sequence of the CSMD3 gene. Comparative genomic analysis revealed a conserved family of CSMD genes in the mouse and fugu genomes. Possible functions of the CSMD gene family are discussed.

  12. A novel interstitial deletion of 2q22.3 q23.3 in a patient with dysmorphic features, epilepsy, aganglionosis, pure red cell aplasia, and skeletal malformations.

    PubMed

    Bravo-Oro, Antonio; Lurie, Iosif W; Elizondo-Cárdenas, Gabriela; Peña-Zepeda, Claudia; Salazar-Martínez, Abel; Correa-González, Cecilia; Castrillo, José Luis; Avila, Silvia; Esmer, Carmen

    2015-08-01

    Many chromosomal deletions encompassing the 2q23.1 region have been described ranging from small deletions of 38 kb up to >19 Mb. Most phenotypic features of the 2q23.1 deletion syndrome are due to a MBD5 gene loss independent of the size of the deletion. Here, we describe a male patient harboring a novel interstitial deletion encompassing the 2q22.3 q23.3 chromosomal region. Array-CGH revealed a 7.1 Mb deletion causing haploinsufficiency of several genes including MBD5, ACVR2, KIF5C, and EPC2. This patient presents with additional findings to those already described in individuals who have deletions of MBD5 including toes absence of halluces, pure red cell aplasia, and intestinal aganglionosis. Interestingly, in the deleted region there are previously identified regulatory sequences which are located upstream to ZEB2, which is associated with Hirschsprung disease (HSCR). Several genes have been associated with pure red cell aplasia, but to our knowledge, this is the first time that 2q deletion is associated with this phenotype. These additional findings should be added to the list of manifestations associated with 2q deletion, and provide support for the hypothesis that this individual has a true contiguous gene deletion syndrome.

  13. 29 CFR 4010.9 - Financial information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Financial information. 4010.9 Section 4010.9 Labor... DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.9 Financial information... with the instructions on PBGC's Web site, http://www.pbgc.gov, the following financial information...

  14. 7 CFR 4279.137 - Financial statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Financial statements. 4279.137 Section 4279.137... § 4279.137 Financial statements. (a) The lender will determine the type and frequency of submission of financial statements by the borrower. At a minimum, annual financial statements prepared by an accountant...

  15. 7 CFR 3430.56 - Financial reporting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATIVE PROVISIONS Post-Award and Closeout § 3430.56 Financial reporting. (a) SF-269, Financial Status Report. Unless stated differently in the award terms and conditions, a final SF-269, Financial Status... its normal accounting system. When submitting a final SF-269, Financial Status Report, the...

  16. 29 CFR 4010.9 - Financial information.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Financial information. 4010.9 Section 4010.9 Labor... DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.9 Financial information... with the instructions on PBGC's Web site, http://www.pbgc.gov, the following financial information...

  17. 14 CFR 1260.26 - Financial management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Financial management. 1260.26 Section 1260... AGREEMENTS General Provisions § 1260.26 Financial management. Financial Management August 2003 (a) Advance payments through a Letter of Credit will be made by the Financial Management Office of the NASA...

  18. 14 CFR 1260.26 - Financial management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Financial management. 1260.26 Section 1260... AGREEMENTS General Provisions § 1260.26 Financial management. Financial Management August 2003 (a) Advance payments through a Letter of Credit will be made by the Financial Management Office of the NASA...

  19. 14 CFR 1260.26 - Financial management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Financial management. 1260.26 Section 1260... AGREEMENTS General Provisions § 1260.26 Financial management. Financial Management August 2003 (a) Advance payments through a Letter of Credit will be made by the Financial Management Office of the NASA...

  20. Financial Management and Young Australian Workers

    ERIC Educational Resources Information Center

    Dowling, Nicki; Hoiles, Lauren; Corney, Tim; Clark, David

    2008-01-01

    In two studies of young Australian workers, participants generally displayed positive attitudes towards financial management practices; however, a substantial proportion failed to display positive financial management practices, experienced financial problems and dissatisfaction, and reported low rates of seeking financial assistance, particularly…

  1. 12 CFR 563.172 - Financial derivatives.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Financial derivatives. 563.172 Section 563.172 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS ASSOCIATIONS-OPERATIONS Financial Management Policies § 563.172 Financial derivatives. (a) What is a financial...

  2. Adult Financial Capability Framework. Second Edition

    ERIC Educational Resources Information Center

    Basic Skills Agency, 2006

    2006-01-01

    Both the Financial Services Authority and the Basic Skills Agency are committed to supporting those individuals and organisations working to improve the financial capability of themselves and others. The development of the National Strategy for Financial Capability, coordinated by the Financial Services Authority, and the commissioning of a…

  3. 14 CFR 1260.26 - Financial management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Financial management. 1260.26 Section 1260... AGREEMENTS General Provisions § 1260.26 Financial management. Financial Management August 2003 (a) Advance payments through a Letter of Credit will be made by the Financial Management Office of the NASA...

  4. 25 CFR 700.455 - Financial assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Financial assistance. 700.455 Section 700.455 Indians THE... Funds § 700.455 Financial assistance. (a) The Commission may provide financial assistance to applicants eligible under this subpart from funds available for any fiscal year. (b) To obtain financial...

  5. 31 CFR 29.524 - Financial hardship.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Financial hardship. 29.524 Section 29... Waiver of Overpayments § 29.524 Financial hardship. Financial hardship may be deemed to exist when the.... Financial hardship will not be found to exist when the debtor merely establishes that the repayment causes...

  6. 31 CFR 226.6 - Financial reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Financial reports. 226.6 Section 226..., DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE RECOGNITION OF INSURANCE COVERING TREASURY TAX AND LOAN DEPOSITARIES § 226.6 Financial reports. Financial reports of Insurance Organizations shall...

  7. 38 CFR 21.6260 - Financial assistance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Financial assistance. 21.6260 Section 21.6260 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... Recipients Financial Assistance § 21.6260 Financial assistance. (a) Direct financial assistance...

  8. Adolescents' Financial Literacy: The Role of Financial Socialization Agents, Financial Experiences, and Money Attitudes in Shaping Financial Literacy among South Korean Youth

    ERIC Educational Resources Information Center

    Sohn, Sang-Hee; Joo, So-Hyun; Grable, John E.; Lee, Seonglim; Kim, Minjeung

    2012-01-01

    The purpose of this study was to test the relationships between financial socialization agents, financial experiences, money attitudes, demographic characteristics, and the financial literacy of Korean adolescents. Using the 2006 Korean National Financial Literacy Test Survey for Adolescents (N = 1185), a series of regression analyses were…

  9. Quarterly environmental radiological survey summary second quarter 1996 100, 200, 300 and 600 areas

    SciTech Connect

    Dorian, J.J., Westinghouse Hanford

    1996-07-26

    This report provides a summary of the radiological surveys performed in support of the operational environmental monitoring program at the Hanford Site. The Second Quarter 1996 survey results and the status of actions required from current and past reports are summarized below: All the routine environmental radiological surveys scheduled during April, May, and June 1996 were completed. One Hundred twenty- five environmental radiological surveys were performed during the second quarter of 1996, twenty nine at the active waste sites and ninety six at the inactive waste sites. Contamination above background levels Wag found at three of the active waste sites and fifteen of the inactive waste sites. Contamination levels as high as 65,000 disintegrations per minute (dpm) were reported. Of these contaminated surveys seven were in Underground Radioactive Material (URM) areas and one was in an unposted area. The contamination found within three of the URM areas was immediately cleaned up and no further action was required. In the remaining four sites the areas were posted and will require decontamination. At the site where there was no posting, the contamination was below action levels, however, Site Support Services was notified. Radiological Problem Reports (RPR`s) were issued and the sites were turned over to the landlord for further action if required. During the second quarter 1996, 0. 7 hectares (1.7 acres) were stabilized and radiologically down posted from Surface Contamination (SC) to URM. No Compliance Assessment Reports (CARS) were issued for sites found out of compliance with standards identified in WHC-CM-7-5, Environmental Compliance. No Surveillance Compliance/Inspection Reports (SCIR) were closed during the Second Quarter of 1996. Five open SCIRB had not been resolved.

  10. Phase II - photovoltaics for utility scale applications (PVUSA). Quarterly technical report, First quarter 1996

    SciTech Connect

    1996-07-01

    This is the first of three planned quarterly Technical Reports of 1996 system performance and major project activities. The final quarter will be discussed in the 1996 Progress Report. Activity for the PVUSA project was curtailed considerably, pending resolution of the transfer of management to the California Energy Commission (CEC) and the Sacramento Municipal Utility District (SMUD). Principal activities during the first quarter of 1996 included: (1) Continued negotiations regarding the transfer of project management from PG&E to the joint CEC/SMUD team. Primary remaining hurdle is obtaining approval from the California Public Utilities Commission. (2) Provided training to CEC and SMUD project team members on January 8, 9, and 11. Training covered site operations including data acquisition. (3) Completed the draft of the 1995 Progress Report. (4) Supported the contractor in their efforts for enhancing the performance and reliability of the Amonix EMT-3 array at Davis. (5) Reviewed the PSCo installation drawings, and started activities to provide the PVUSA DAS equipment, (6) Operation and maintenance of existing systems, including data collection and reporting. Data were collected for 19 completed systems with a combined capacity of 1,800 kW. Combined, these systems generated nearly 1.1 million kWh during January through March. The project`s cumulative generation now stands at 8.2 million kWh. Key cumulative 1996 results are listed in the following table. The locations of systems other than Davis are noted alongside the supplier`s name.

  11. The AMTEX Partnership. Third quarter report

    SciTech Connect

    Not Available

    1994-06-01

    The AMTEX Partnership is a collaborative research and development program among the U.S. Integrated Textile Industry, the Department of Energy, The DOE laboratories, other federal agencies and laboratories, and universities. The goal of AMTEX is to strengthen the competitiveness of this vital U.S. industry and thereby preserve and create American jobs. During the third quarter of 1994 all the Cooperative Research and Development Agreements (CRADAs) were completed and work initiated for three additional projects: Computer Aided Fabric Evaluation (CAFE), Textile Resource Conservation (TReC), and Sensors for Agile Manufacturing (SFAM). The plan for a Cotton Biotechnology project was completed and reviewed by the Industry Technical Advisory Committee. In addition, an `impact study` on the topic of flexible fiber production was conducted by an industry group led by the fiber manufacturers.

  12. Single-pole ladder at quarter filling

    NASA Astrophysics Data System (ADS)

    Aristov, D. N.; Kiselev, M. N.; Kikoin, K.

    2007-06-01

    We study the ground state and excitation spectrum of a quasi-one-dimensional system consisting of a pole and rungs oriented in opposite directions (“centipede ladder,” CL) at quarter filling. The spin and charge excitation spectra are found in the limits of small and large longitudinal hoppings t‖ compared to the on-rung hopping rate t⊥ and exchange coupling I⊥ . At small t‖ , the system with ferromagnetic on-rung exchange demonstrates instability against dimerization. Coherent propagation of charge-transfer excitons is possible in this limit. At large t‖ , CL behaves like two-orbital Hubbard chain, but the gap opens in the charge excitation spectrum, thus reducing the symmetry from SU(4) to SU(2). The spin excitations are always gapless and their dispersion changes from quadratic magnonlike for ferromagnetic on-rung exchange to linear spinonlike for antiferromagnetic on-rung exchange in weak longitudinal hopping limit.

  13. A bulk niobium superconducting quarter wave resonator

    SciTech Connect

    Ben-Zvi, I. ); Chiaveri, E. ); Elkonin, B.V. ); Facco, A.; Sokolowski, J.S. . Lab. Nazionale di Legnaro)

    1990-01-01

    A bath-cooled all-niobium 160 MHz quarter wave resonator prototype was constructed and tested. The objective of this research has been the development of a high performance accelerating element with {beta}{sub opt} {approx equal} 0.11 for the ALPI linac at the Laboratori Nazionali di Legnaro. The design of this resonator was based upon a previous 150 MHz model, with minor changes due to the different frequency and to modified welding procedure. An accelerating field of 5 MV/m was achieved at a power dissipation of 10 W and the low power Q was 2.4 {times} 10{sup 8}. The resonator could dissipate 70 W of power without thermal breakdown. 16 refs., 2 figs., 1 tab.

  14. Department of Energy quarterly technical report

    SciTech Connect

    Anderson, R.N.

    1995-04-15

    The objective is to test the concept that the growth faults in Eugene Island Block 330 (EI-330 field) are conduits through which producing reservoirs are charged and that enhanced production can be developed by producing directly from the fault zone. The site, operated by Penzoil, is located in 250 feet of water and the productive depth intervals include 4000 to 9000 feet. The field demonstration will be accomplished by drilling and production testing of growth fault systems associated with the EI-330 field. The project utilizes advanced 3-D seismic analysis, geochemical studies, structural and stratigraphic reservoir characterization, reservoir simulation, compact visualization systems. In this quarterly report, progress reports are presented for the following tasks: database management; reservoir characterization; modeling; geochemistry; and data integration.

  15. Internal Arrangement of Skylab Workshop Crew Quarters

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This image depicts a layout of the Skylab workshop 1-G trainer crew quarters. At left, in the sleep compartment, astronauts slept strapped to the walls of cubicles and showered at the center. Next right was the waste management area where wastes were processed and disposed. Upper right was the wardroom where astronauts prepared their meals and foods were stored. In the experiment operation area, upper left, against the far wall, was the lower-body negative-pressure device (Skylab Experiment M092) and the Ergometer for the vectorcardiogram experiment (Skylab Experiment M063). The trainers and mockups were useful in the developmental phase, while engineers and astronauts were still working out optimum designs. They provided much data applicable to the manufacture of the flight articles.

  16. Quarterly progress report, July-September 1982

    SciTech Connect

    Not Available

    1982-01-01

    Our ability to characterize fuel shells was greatly improved this quarter by the installation of the Eikonix Image Acquisition System. Linking this system to the VAX 11/750 computer permits real-time imaging of radiographic plates. Analysis of the thermal transport experimental campaign continued. We found that the mass-ablation rate was significantly higher for spherical targets than for planar targets. The ablation rate was also greater for 0.53 ..mu..m light used in similar experiments performed earlier. The analysis of the emission of light at 3/2 omego/sub 0/ and of the two-lobe feature detected in the thermal transport experiments has been examined and found to be consistent with the theory for two-plasmon decay. Further analysis of stimulated Brillouin scattering has shown the quenching of the process through a secondary process involving the decay of the primary ion acoustic wave into two secondary ion waves.

  17. Natural gas imports and exports, first quarter report 2000

    SciTech Connect

    2000-06-01

    The Office of Natural Gas and Petroleum Import and Export Activities prepares quarterly reports showing natural gas import and export activity. Companies are required to file quarterly reports. Attachments show the percentage of takes to maximum firm contract levels and the weighted average per unit price for each of the long-term importers during the 5 most recent reporting quarters, volumes and prices of gas purchased by long-term importers and exporters during the past 12 months, volume and price data for gas imported on a short-term or spot market basis, and the gas exported on a short-term or spot market basis to Canada and Mexico.

  18. 5. Photographic copy of architectural floor plans for Officers' Quarters ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photographic copy of architectural floor plans for Officers' Quarters "A" & "B": Taylor & Barnes, Architects & Engineers, 803 W. Third Street, Los Angeles California, O.C.E. Office of Civil Engineer Job No. Muroc ESA 210-48 and 210-49, Military Construction: Muroc Flight Test Base, Muroc, California, Warehouses and Additional Housing for Officers: Officers Quarters, Floor Plan, Foundation Plan & Details, Sheet No. 12 of 16, May 1945. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, Officers' Quarters A, North Base Road, Boron, Kern County, CA

  19. 6. Photographic copy of architectural elevations for Officers' Quarters "A" ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photographic copy of architectural elevations for Officers' Quarters "A" & "B": Taylor & Barnes, Architects & Engineers, 803 W. Third Street, Los Angeles California, O.C.E. Office of Civil Engineer Job No. Muroc ESA 210-48 and 210-49, Military Construction: Muroc Flight Test Base, Muroc, California, Warehouses and Additional Housing for Officers: Officers Quarters, Elevations & Details, Sheet No. 13 of 16, May 1945. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, Officers' Quarters A, North Base Road, Boron, Kern County, CA

  20. Metallurgical Laboratory (HWMF) Groundwater Monitoring Report, Fourth Quarter 1994

    SciTech Connect

    Chase, J.A.

    1995-03-01

    Groundwater flow direction and rate in the M-Area Aquifer Zone were similar to previous quarters. Conditions affecting determination of groundwater flow directions and rates in the Upper Lost Lake Aquifer Zone, Lower Lost Lake Aquifer Zone, and the Middle Sand Aquifer Zone of the Crouch Branch Confining Units were also similar to previous quarters. During second quarter 1994, SRS received South Carolina Department of Health and Environmental Control approval for constructing five point-of-compliance wells and two plume definition wells near the Met Lab Hazardous Waste Management Facility. This project began in July 1994 and is complete; however, analytical data from these wells are not yet available.

  1. Natural gas imports and exports, third quarter report 2000

    SciTech Connect

    2000-12-01

    The Office of Natural Gas and Petroleum Import and Export Activities prepares quarterly reports showing natural gas import and export activity. Companies are required to file quarterly reports. Attachments show the percentage of takes to maximum firm contract levels and the weighted average per unit price for each of the long-term importers during the 5 most recent quarters, volumes and prices of gas purchased by long-term importers and exporters during the past 12 months, volume and price data for gas imported on a short-term or spot market basis, and the gas exported on a short-term or spot market basis to Canada and Mexico.

  2. Natural gas imports and exports, fourth quarter report 1999

    SciTech Connect

    2000-03-01

    The Office of Natural Gas and Petroleum Import and Export Activities prepares quarterly reports showing natural gas import and export activity. Companies are required to file quarterly reports. Attachments show the percentage of takes to maximum firm contract levels and the weighted average per unit price for each of the long-term importers during the five most recent quarters, volumes and prices of gas purchased by long-term importers and exporters during the past 12 months, volume and price data for gas imported on a short-term or spot market basis, and the gas exported on a short-term or spot market basis to Canada and Mexico.

  3. Patients' perspective of financial benefits following head and neck cancer in Merseyside and Cheshire.

    PubMed

    Rogers, S N; Harvey-Woodworth, C N; Lowe, D

    2012-07-01

    The aim of this interview study was to ask patients with head and neck cancer in the Mersey region about their need for financial benefits, the advice they were given about benefits and financial matters, and the financial burden of the disease. Stratified quota sampling was by employment status, whether work had been affected by the cancer, and by sex. Of 51 interviewees (mean (SD) age 61(8) years) 20 were retired, 11 were unemployed, 13 worked full-time, and 7 worked part-time. Cancer had affected the work status of 24. Since diagnosis 57% had suffered financially; this was particularly high in those who had retired (65%), and in those whose work had been affected by cancer (79%). Quality of life had decreased in 53% as a result of the financial impact of the disease. This was most common in the unemployed (64%), and in those whose work was affected by cancer (83%). Only a quarter had been given adequate help and information about finance; this was lowest in the unemployed (18%) and highest in those who were fully employed (39%). One third (17/51) had never claimed benefits. The most common benefits were Disability Living Allowance and Incapacity Benefit. Two-thirds (21/31) had applied for benefits after diagnosis, 18 of these were directly as a result of the disease. The median (IQR) weekly income from benefits was £88 (£60-170). Patients and carers need better access to financial advice. We suggest that each multidisciplinary team should have a designated benefits or financial advisor who is readily available to patients in the clinic and on the ward.

  4. Financial Stress, Self-Efficacy, and Financial Help-Seeking Behavior of College Students

    ERIC Educational Resources Information Center

    Lim, HanNa; Heckman, Stuart J.; Letkiewicz, Jodi C.; Montalto, Catherine P.

    2014-01-01

    Financial stress and self-efficacy are examined in relationship to college students' financial help-seeking behavior utilizing Grable and Joo's (1999) framework. A cognitive approach is taken by focusing on the moderating role of financial self-efficacy on the relationship between financial stress and financial help-seeking. Data from…

  5. 78 FR 29399 - ERNY Financial ETF Trust and ERNY Financial Advisors, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... COMMISSION ERNY Financial ETF Trust and ERNY Financial Advisors, LLC; Notice of Application May 13, 2013... Financial ETF Trust (``Trust'') and ERNY Financial Advisors, LLC (``Adviser''). Summary of Application... and/or Sub-Advisers. \\4\\ Depositary Receipts are typically issued by a financial institution,...

  6. How Has the Affordable Care Act Affected Health Insurers' Financial Performance?

    PubMed

    Hall, Mark A; McCue, Michael J

    2016-07-01

    Starting in 2014, the Affordable Care Act transformed the market for individual health insurance by changing how insurance is sold and by subsidizing coverage for millions of new purchasers. Insurers, who had no previous experience under these market conditions, competed actively but faced uncertainty in how to price their products. This issue brief uses newly available data to understand how health insurers fared financially during the ACA's first year of full reforms. Overall, health insurers' financial performance began to show some strain in 2014, but the ACA's reinsurance program substantially buffered the negative effects for most insurers. Although a quarter of insurers did substantially worse than others, experience under the new market rules could improve the accuracy of pricing decisions in subsequent years. PMID:27459740

  7. How Has the Affordable Care Act Affected Health Insurers' Financial Performance?

    PubMed

    Hall, Mark A; McCue, Michael J

    2016-07-01

    Starting in 2014, the Affordable Care Act transformed the market for individual health insurance by changing how insurance is sold and by subsidizing coverage for millions of new purchasers. Insurers, who had no previous experience under these market conditions, competed actively but faced uncertainty in how to price their products. This issue brief uses newly available data to understand how health insurers fared financially during the ACA's first year of full reforms. Overall, health insurers' financial performance began to show some strain in 2014, but the ACA's reinsurance program substantially buffered the negative effects for most insurers. Although a quarter of insurers did substantially worse than others, experience under the new market rules could improve the accuracy of pricing decisions in subsequent years.

  8. A study of financial incentives to reduce plasma HIV RNA among patients in care.

    PubMed

    Farber, Steven; Tate, Janet; Frank, Cyndi; Ardito, David; Kozal, Michael; Justice, Amy C; Scott Braithwaite, R

    2013-09-01

    The role of financial incentives in HIV care is not well studied. We conducted a single-site study of monetary incentives for viral load suppression, using each patient as his own control. The incentive size ($100/quarter) was designed to be cost-neutral, offsetting estimated downstream costs averted through reduced HIV transmission. Feasibility outcomes were clinic workflow, patient acceptability, and patient comprehension. Although the study was not powered for effectiveness, we also analyzed viral load suppression. Of 80 eligible patients, 77 consented, and 69 had 12 month follow-up. Feasibility outcomes showed minimal impact on patient workflow, near-unanimous patient acceptability, and satisfactory patient comprehension. Among individuals with detectable viral loads pre-intervention, the proportion of undetectable viral load tests increased from 57 to 69 % before versus after the intervention. It is feasible to use financial incentives to reward ART adherence, and to specify the incentive by requiring cost-neutrality and targeting biological outcomes.

  9. Threats to financial system security

    SciTech Connect

    McGovern, D.E.

    1997-06-01

    The financial system in the United States is slowly migrating from the bricks and mortar of banks on the city square to branch banks, ATM`s, and now direct linkage through computers to the home. Much work has been devoted to the security problems inherent in protecting property and people. The impact of attacks on the information aspects of the financial system has, however, received less attention. Awareness is raised through publicized events such as the junk bond fraud perpetrated by Milken or gross mismanagement in the failure of the Barings Bank through unsupervised trading activities by Leeson in Singapore. These events, although seemingly large (financial losses may be on the order of several billion dollars), are but small contributors to the estimated $114 billion loss to all types of financial fraud in 1993. Most of the losses can be traced to the contribution of many small attacks perpetrated against a variety of vulnerable components and systems. This paper explores the magnitude of these financial system losses and identifies new areas for security to be applied to high consequence events.

  10. A 46,X,der(X)t(X;Y)(p22.3;q11.2) karyotype found in a newborn with microcornea and sclerocornea: An example of the MLS/Goltz/Aicardi contiguous gene syndrome?

    SciTech Connect

    Milatovich, A.; Becker, T.; Kaufman, A.

    1994-09-01

    There have been 15 reports in the literature of patients with microphthalmia and linear skin defects (MLS) who have deletions of the distal region of the short arm of the X chromosome, Xp22.3-pter. Since there appears to be some overlap of features between MLS, Goltz and Aicardi syndromes, it has been suggested that these syndromes represent a contiguous gene syndrome. At least three individuals have been reported with t(X;Y) and some common clinical features. We have seen a female infant with several anterior chamber anomalies including microcornea and sclerocornea, who also has an unbalanced translocation between the X and Y chromosomes, 46,X,der(X)t(X;Y) (p22.3;q11.2). Q-banding and fluorescence in situ hybridization (FISH) with a Y chromosome cocktail (Oncor) confirmed the identity of this derivative chromosome. X-inactivation studies done by RBG-banding showed that the der(X) is preferentially inactivated in all 50 metaphase cells examined from PHA-stimulated lymphocytes. It is likely some gene(s) on the distal Xp do not escape inactivation and when deleted result in anterior chamber abnormalities. X-inactivation patterns may be different in different tissues or at different times during development. Molecular studies will be helpful in determining what gene(s) are actually deleted in this case. This case is important because the clinical findings are limited to the development of the eyes and may help to define the critical regions and/or minimum region of overlap among MLS, Goltz and Aicardi syndromes.

  11. Major Loci on Chromosomes 8q and 3q Control Interferon γ Production Triggered by Bacillus Calmette-Guerin and 6-kDa Early Secretory Antigen Target, Respectively, in Various Populations

    PubMed Central

    Jabot-Hanin, Fabienne; Cobat, Aurélie; Feinberg, Jacqueline; Grange, Ghislain; Remus, Natascha; Poirier, Christine; Boland-Auge, Anne; Besse, Céline; Bustamante, Jacinta; Boisson-Dupuis, Stéphanie; Casanova, Jean-Laurent; Schurr, Erwin; Alcaïs, Alexandre; Hoal, Eileen G.; Delacourt, Christophe; Abel, Laurent

    2016-01-01

    Background. Interferon γ (IFN-γ) release assays (IGRAs) provide an in vitro measurement of antimycobacterial immunity that is widely used as a test for Mycobacterium tuberculosis infection. IGRA outcomes are highly heritable in various populations, but the nature of the involved genetic factors remains unknown. Methods. We conducted a genome-wide linkage analysis of IGRA phenotypes in families from a tuberculosis household contact study in France and a replication study in families from South Africa to confirm the loci identified. Results. We identified a major locus on chromosome 8q controlling IFN-γ production in response to stimulation with live bacillus Calmette-Guerin (BCG; LOD score, 3.81; P = 1.40 × 10−5). We also detected a second locus, on chromosome 3q, that controlled IFN-γ levels in response to stimulation with 6-kDa early secretory antigen target, when accounting for the IFN-γ production shared with that induced by BCG (LOD score, 3.72; P = 1.8 × 10−5). Both loci were replicated in South African families, where tuberculosis is hyperendemic. These loci differ from those previously identified as controlling the response to the tuberculin skin test (TST1 and TST2) and the production of TNF-α (TNF1). Conclusions. The identification of 2 new linkage signals in populations of various ethnic origins living in different M. tuberculosis exposure settings provides new clues about the genetic control of human antimycobacterial immunity. PMID:26690346

  12. The gene for spinal cerebellar ataxia 3 (SCA3) is located in a region of {approximately} 3 cM on chromosome 14q24.3-q32.2

    SciTech Connect

    Stevanin, G.; Cancel, G.; Duerr, A.; Dubourg, O.; Agid, Y.; Brice, A.; Chneiweiss, H.; Weissenbach, J.; Cann, H.M.

    1995-01-01

    SCA3, the gene for spinal cerebellar ataxia 3, was recently mapped to a 15-cM interval between D14S67 and D14S81 on chromosome 14q, by linkage analysis in two families of French ancestry. The SCA3 candidate region has now been refined by linkage analysis with four new microsatellite markers (D14S256, D14S291, D14S280, and AFM343vf1) in the same two families, in which 19 additional individuals were genotyped, and in a third French family. Combined two-point linkage analyses show that the new markers, D14S280 and AFM343vf1, are tightly linked to the SCA3 locus, with maximal lod scores, at recombination fraction, ({theta}) = .00, of 7.05 and 13.70, respectively. Combined multipoint and recombinant haplotype analyses localize the SCA3 locus to a 3-cM interval flanked by D14S291 and D14S81. The same allele for D14S280 segregates with the disease locus in the three kindreds. This allele is frequent in the French population, however, and linkage disequilibrium is not clearly established. The SCA3 locus remains within the 29-cM region on 14q24.3-q32.2 containing the gene for the Machado-Joseph disease, which is clinically related to the phenotype determined by SCA3, but it cannot yet be concluded that both diseases result from alterations of the same gene. 30 refs., 3 figs., 3 tabs.

  13. Sociology, history, and philosophy in the Research Quarterly.

    PubMed

    Sage, George H; Dyreson, Mark S; Kretchmar, R Scott

    2005-06-01

    The accounts of our subdiscipline's contributions to The Research Quarterly are similar. Sociology, history, and philosophy operate at some distance from the biological sciences. The research methods used by scholars in each of our domains address distinctive issues related to objectivity and, thus, validity. Our contributions to The Research Quarterly have been modest, numbering about 240 articles, or slightly over 3 per volume. In short, we have enjoyed only a minority presence in The Research Quarterly during its 75 years of existence. Our stories, however, also diverge in important ways. Our research methods are different, and our relationships with our parent disciplines are not the same. In addition, our perceptions of The Research Quarterly as a potential repository for our respective publications vary considerably.

  14. 1. THREE QUARTERS VIEW OF THE LIBRARY BUILDING. THE MAIN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. THREE QUARTERS VIEW OF THE LIBRARY BUILDING. THE MAIN ENTRANCE IS ON THE LEFT, FACING FORTH STREET - Anaconda Historic District, Hearst Free Library, Fourth & Main Streets, Anaconda, Deer Lodge County, MT

  15. Solar Energy Technologies Program Newsletter - Fourth Quarter 2009

    SciTech Connect

    DOE Solar Energy Technologies Program

    2009-12-31

    The Fourth Quarter 2009 edition of the Solar Energy Technologies Program newsletter summarizes the activities for the past three months, funding opportunities, highlights from the national labs, and upcoming events.

  16. Servant's quarters, west wing, upper floor interior, looking to south. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Servant's quarters, west wing, upper floor interior, looking to south. Doorway at center connects with the Majordomo's sleeping space. - Vallejo Adobe, Adobe Road at Casa Grande, Petaluma, Sonoma County, CA

  17. Solar Energy Technologies Program Newsletter - First Quarter 2010

    SciTech Connect

    2010-04-22

    The first quarter 2010 edition of the Solar Energy Technologies Program newsletter summarizes the activities for the past three months, funding opportunities, highlights from the national labs, and upcoming events.

  18. 13. CO'S STATEROOM (CABIN'S QUARTERS), PORT EXTERIOR. NOTE PORTHOLE AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. CO'S STATEROOM (CABIN'S QUARTERS), PORT EXTERIOR. NOTE PORTHOLE AND WOODEN FRAME WINDOWS. - U.S. Coast Guard Cutter WHITE LUPINE, U.S. Coast Guard Station Rockland, east end of Tillson Avenue, Rockland, Knox County, ME

  19. 1. THREE QUARTERS VIEW OF THE DURSTON BUILDING LOOKING SOUTHEAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. THREE QUARTERS VIEW OF THE DURSTON BUILDING LOOKING SOUTHEAST. ONE OF THE ORIGINAL STOREFRONTS REMAINS IN PLACE ON THE MAIN STREET FACADE - Anaconda Historic District, Durston Building, Main Street & East Park Avenue, Anaconda, Deer Lodge County, MT

  20. 21. Interior second level view of representative quarters for officers ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Interior second level view of representative quarters for officers and Chief Petty Officers. - Naval Torpedo Station, Firing Pier, North end of Gould Island in Narragansett Bay, Newport, Newport County, RI