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Sample records for 3d conduction effects

  1. Methodology for the Assessment of 3D Conduction Effects in an Aerothermal Wind Tunnel Test

    NASA Technical Reports Server (NTRS)

    Oliver, Anthony Brandon

    2010-01-01

    This slide presentation reviews a method for the assessment of three-dimensional conduction effects during test in a Aerothermal Wind Tunnel. The test objectives were to duplicate and extend tests that were performed during the 1960's on thermal conduction on proturberance on a flat plate. Slides review the 1D versus 3D conduction data reduction error, the analysis process, CFD-based analysis, loose coupling method that simulates a wind tunnel test run, verification of the CFD solution, Grid convergence, Mach number trend, size trends, and a Sumary of the CFD conduction analysis. Other slides show comparisons to pretest CFD at Mach 1.5 and 2.16 and the geometries of the models and grids.

  2. Effect of Weaving Direction of Conductive Yarns on Electromagnetic Performance of 3D Integrated Microstrip Antenna

    NASA Astrophysics Data System (ADS)

    Xu, Fujun; Yao, Lan; Zhao, Da; Jiang, Muwen; Qiu, Yipping

    2013-10-01

    A three-dimensionally integrated microstrip antenna (3DIMA) is a microstrip antenna woven into the three-dimensional woven composite for load bearing while functioning as an antenna. In this study, the effect of weaving direction of conductive yarns on electromagnetic performance of 3DIMAs are investigated by designing, simulating and experimental testing of two microstrip antennas with different weaving directions of conductive yarns: one has the conductive yarns along the antenna feeding direction (3DIMA-Exp1) and the other has the conductive yarns perpendicular the antenna feeding direction (3DIMA-Exp2). The measured voltage standing wave ratio (VSWR) of 3DIMA-Exp1 was 1.4 at the resonant frequencies of 1.39 GHz; while that of 3DIMA-Exp2 was 1.2 at the resonant frequencies of 1.35 GHz. In addition, the measured radiation pattern of the 3DIMA-Exp1 has smaller back lobe and higher gain value than those of the 3DIMA-Exp2. This result indicates that the waving direction of conductive yarns may have a significant impact on electromagnetic performance of textile structural antennas.

  3. Full 3-D TLM simulations of the Earth-ionosphere cavity: Effect of conductivity on the Schumann resonances

    NASA Astrophysics Data System (ADS)

    Toledo-Redondo, S.; Salinas, A.; Fornieles, J.; Portí, J.; Lichtenegger, H. I. M.

    2016-06-01

    Schumann resonances can be found in planetary atmospheres, inside the cavity formed by the conducting surface of the planet and the lower ionosphere. They are a powerful tool to investigate both the electric processes that occur in the atmosphere and the characteristics of the surface and the lower ionosphere. Results from a full 3-D model of the Earth-ionosphere electromagnetic cavity based on the Transmission-Line Modeling (TLM) method are presented. A Cartesian scheme with homogeneous cell size of 10 km is used to minimize numerical dispersion present in spherical schemes. Time and frequency domain results have been obtained to study the resonance phenomenon. The effect of conductivity on the Schumann resonances in the cavity is investigated by means of numerical simulations, studying the transition from resonant to nonresonant response and setting the conductivity limit for the resonances to develop inside the cavity. It is found that the transition from resonant to nonresonant behavior occurs for conductivity values above roughly 10-9 S/m. For large losses in the cavity, the resonances are damped, but, in addition, the peak frequencies change according to the local distance to the source and with the particular electromagnetic field component. These spatial variations present steep variations around each mode's nodal position, covering distances around 1/4 of the mode wavelength, the higher modes being more sensitive to this effect than the lower ones. The dependence of the measured frequency on the distance to the source and particular component of the electric field offers information on the source generating these resonances.

  4. Reduction of Thermal Conductivity by Nanoscale 3D Phononic Crystal

    PubMed Central

    Yang, Lina; Yang, Nuo; Li, Baowen

    2013-01-01

    We studied how the period length and the mass ratio affect the thermal conductivity of isotopic nanoscale three-dimensional (3D) phononic crystal of Si. Simulation results by equilibrium molecular dynamics show isotopic nanoscale 3D phononic crystals can significantly reduce the thermal conductivity of bulk Si at high temperature (1000 K), which leads to a larger ZT than unity. The thermal conductivity decreases as the period length and mass ratio increases. The phonon dispersion curves show an obvious decrease of group velocities in 3D phononic crystals. The phonon's localization and band gap is also clearly observed in spectra of normalized inverse participation ratio in nanoscale 3D phononic crystal. PMID:23378898

  5. Reduction of thermal conductivity by nanoscale 3D phononic crystal.

    PubMed

    Yang, Lina; Yang, Nuo; Li, Baowen

    2013-01-01

    We studied how the period length and the mass ratio affect the thermal conductivity of isotopic nanoscale three-dimensional (3D) phononic crystal of Si. Simulation results by equilibrium molecular dynamics show isotopic nanoscale 3D phononic crystals can significantly reduce the thermal conductivity of bulk Si at high temperature (1000 K), which leads to a larger ZT than unity. The thermal conductivity decreases as the period length and mass ratio increases. The phonon dispersion curves show an obvious decrease of group velocities in 3D phononic crystals. The phonon's localization and band gap is also clearly observed in spectra of normalized inverse participation ratio in nanoscale 3D phononic crystal.

  6. Optical conductivity renormalization of graphene on SrTiO 3 due to resonant excitonic effects mediated by Ti 3 d orbitals

    NASA Astrophysics Data System (ADS)

    Gogoi, Pranjal Kumar; Trevisanutto, Paolo E.; Yang, Ming; Santoso, Iman; Asmara, Teguh Citra; Terentjevs, Aleksandrs; Della Sala, Fabio; Breese, Mark B. H.; Venkatesan, T.; Feng, Yuan Ping; Loh, Kian Ping; Neto, Antonio H. Castro; Rusydi, Andrivo

    2015-01-01

    We present evidence of a drastic renormalization of the optical conductivity of graphene on SrTiO 3 resulting in almost full transparency in the ultraviolet region. These findings are attributed to resonant excitonic effects further supported by ab initio Bethe-Salpeter equation and density functional theory calculations. The (π ,π *) orbitals of graphene and Ti-3 d t2 g orbitals of SrTiO 3 are strongly hybridized and the interactions of electron-hole states residing in those orbitals play dominant role in the graphene optical conductivity. These interactions are present much below the optical band gap of bulk SrTiO 3. These results open a possibility of manipulating interaction strengths in graphene via d orbitals, which could be crucial for optical applications.

  7. 3D conductive nanocomposite scaffold for bone tissue engineering.

    PubMed

    Shahini, Aref; Yazdimamaghani, Mostafa; Walker, Kenneth J; Eastman, Margaret A; Hatami-Marbini, Hamed; Smith, Brenda J; Ricci, John L; Madihally, Sundar V; Vashaee, Daryoosh; Tayebi, Lobat

    2014-01-01

    Bone healing can be significantly expedited by applying electrical stimuli in the injured region. Therefore, a three-dimensional (3D) ceramic conductive tissue engineering scaffold for large bone defects that can locally deliver the electrical stimuli is highly desired. In the present study, 3D conductive scaffolds were prepared by employing a biocompatible conductive polymer, ie, poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate) (PEDOT:PSS), in the optimized nanocomposite of gelatin and bioactive glass. For in vitro analysis, adult human mesenchymal stem cells were seeded in the scaffolds. Material characterizations using hydrogen-1 nuclear magnetic resonance, in vitro degradation, as well as thermal and mechanical analysis showed that incorporation of PEDOT:PSS increased the physiochemical stability of the composite, resulting in improved mechanical properties and biodegradation resistance. The outcomes indicate that PEDOT:PSS and polypeptide chains have close interaction, most likely by forming salt bridges between arginine side chains and sulfonate groups. The morphology of the scaffolds and cultured human mesenchymal stem cells were observed and analyzed via scanning electron microscope, micro-computed tomography, and confocal fluorescent microscope. Increasing the concentration of the conductive polymer in the scaffold enhanced the cell viability, indicating the improved microstructure of the scaffolds or boosted electrical signaling among cells. These results show that these conductive scaffolds are not only structurally more favorable for bone tissue engineering, but also can be a step forward in combining the tissue engineering techniques with the method of enhancing the bone healing by electrical stimuli.

  8. 3D conductive nanocomposite scaffold for bone tissue engineering

    PubMed Central

    Shahini, Aref; Yazdimamaghani, Mostafa; Walker, Kenneth J; Eastman, Margaret A; Hatami-Marbini, Hamed; Smith, Brenda J; Ricci, John L; Madihally, Sundar V; Vashaee, Daryoosh; Tayebi, Lobat

    2014-01-01

    Bone healing can be significantly expedited by applying electrical stimuli in the injured region. Therefore, a three-dimensional (3D) ceramic conductive tissue engineering scaffold for large bone defects that can locally deliver the electrical stimuli is highly desired. In the present study, 3D conductive scaffolds were prepared by employing a biocompatible conductive polymer, ie, poly(3,4-ethylenedioxythiophene) poly(4-styrene sulfonate) (PEDOT:PSS), in the optimized nanocomposite of gelatin and bioactive glass. For in vitro analysis, adult human mesenchymal stem cells were seeded in the scaffolds. Material characterizations using hydrogen-1 nuclear magnetic resonance, in vitro degradation, as well as thermal and mechanical analysis showed that incorporation of PEDOT:PSS increased the physiochemical stability of the composite, resulting in improved mechanical properties and biodegradation resistance. The outcomes indicate that PEDOT:PSS and polypeptide chains have close interaction, most likely by forming salt bridges between arginine side chains and sulfonate groups. The morphology of the scaffolds and cultured human mesenchymal stem cells were observed and analyzed via scanning electron microscope, micro-computed tomography, and confocal fluorescent microscope. Increasing the concentration of the conductive polymer in the scaffold enhanced the cell viability, indicating the improved microstructure of the scaffolds or boosted electrical signaling among cells. These results show that these conductive scaffolds are not only structurally more favorable for bone tissue engineering, but also can be a step forward in combining the tissue engineering techniques with the method of enhancing the bone healing by electrical stimuli. PMID:24399874

  9. Acoustic patterning for 3D embedded electrically conductive wire in stereolithography

    NASA Astrophysics Data System (ADS)

    Erdem Yunus, Doruk; Sohrabi, Salman; He, Ran; Shi, Wentao; Liu, Yaling

    2017-04-01

    In this paper, we reported a new approach for particle assembly with acoustic tweezers during three-dimensional (3D) printing, for the fabrication of embedded conductive wires with 3D structures. A hexagon shaped acoustic tweezer was incorporated with a digital light processing based stereolithography printer to pattern conductive lines via aligning and condensing conductive nanoparticles. The effect of filler content on electrical resistivity and pattern thickness were studied for copper, magnetite nanoparticles, and carbon nanofiber reinforced nanocomposite samples. The obtained data was later used to produce examples of conductive 3D microstructures and embedded electronic components by using the suggested method.

  10. Calculation of effective conductivity of 2D and 3D composite materials with anisotropic constituents and different inclusion shapes in Mathematica

    NASA Astrophysics Data System (ADS)

    Gómez-Muñoz, José Luis; Bravo-Castillero, Julián

    2008-08-01

    The study of the effective properties of composite materials with anisotropic constituents and different inclusion shapes has motivated the development of the Mathematica 6.0 package "CompositeMaterials". This package can be used to calculate the effective anisotropic conductivity tensor of two-phase composites. Any fiber cross section, even percolating ones, can be studied in the 2D composites. "Rectangular Prism" and "Ellipsoidal" inclusion shapes with arbitrary orientations can be investigated in the 3D composites. This package combines the Asymptotic Homogenization Method and the Finite Element Method in order to obtain the effective conductivity tensor. The commands and options of the package are illustrated with two sample applications for two- and three-dimensional composites. Program summaryProgram title:CompositeMaterials Catalogue identifier:AEAU_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEAU_v1_0.html Program obtainable from:CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions:Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.:132 183 No. of bytes in distributed program, including test data, etc.:1 334 908 Distribution format:tar.gz Programming language:Mathematica 6.0 Computer:Any that can run Mathematica 6.0 and where the open-source free C-programs Triangle ( http://www.cs.cmu.edu/ quake/triangle.html) and TetGen ( http://tetgen.berlios.de/) can be compiled and executed. Tested in Intel Pentium computers. Operating system:Any that can run Mathematica 6.0 and where the open-source free C-programs Triangle ( http://www.cs.cmu.edu/ quake/triangle.html) and TetGen ( http://tetgen.berlios.de/) can be compiled and executed. Tested in Windows XP. RAM:Small two-dimensional calculations require less than 100 MB. Large three-dimensional calculations require 500 MB or more. Classification:7.9 External routines:One Mathematica Add-on and

  11. Effect of viewing distance on 3D fatigue caused by viewing mobile 3D content

    NASA Astrophysics Data System (ADS)

    Mun, Sungchul; Lee, Dong-Su; Park, Min-Chul; Yano, Sumio

    2013-05-01

    With an advent of autostereoscopic display technique and increased needs for smart phones, there has been a significant growth in mobile TV markets. The rapid growth in technical, economical, and social aspects has encouraged 3D TV manufacturers to apply 3D rendering technology to mobile devices so that people have more opportunities to come into contact with many 3D content anytime and anywhere. Even if the mobile 3D technology leads to the current market growth, there is an important thing to consider for consistent development and growth in the display market. To put it briefly, human factors linked to mobile 3D viewing should be taken into consideration before developing mobile 3D technology. Many studies have investigated whether mobile 3D viewing causes undesirable biomedical effects such as motion sickness and visual fatigue, but few have examined main factors adversely affecting human health. Viewing distance is considered one of the main factors to establish optimized viewing environments from a viewer's point of view. Thus, in an effort to determine human-friendly viewing environments, this study aims to investigate the effect of viewing distance on human visual system when exposing to mobile 3D environments. Recording and analyzing brainwaves before and after watching mobile 3D content, we explore how viewing distance affects viewing experience from physiological and psychological perspectives. Results obtained in this study are expected to provide viewing guidelines for viewers, help ensure viewers against undesirable 3D effects, and lead to make gradual progress towards a human-friendly mobile 3D viewing.

  12. Estimation of the thermal conductivity of hemp based insulation material from 3D tomographic images

    NASA Astrophysics Data System (ADS)

    El-Sawalhi, R.; Lux, J.; Salagnac, P.

    2016-08-01

    In this work, we are interested in the structural and thermal characterization of natural fiber insulation materials. The thermal performance of these materials depends on the arrangement of fibers, which is the consequence of the manufacturing process. In order to optimize these materials, thermal conductivity models can be used to correlate some relevant structural parameters with the effective thermal conductivity. However, only a few models are able to take into account the anisotropy of such material related to the fibers orientation, and these models still need realistic input data (fiber orientation distribution, porosity, etc.). The structural characteristics are here directly measured on a 3D tomographic image using advanced image analysis techniques. Critical structural parameters like porosity, pore and fiber size distribution as well as local fiber orientation distribution are measured. The results of the tested conductivity models are then compared with the conductivity tensor obtained by numerical simulation on the discretized 3D microstructure, as well as available experimental measurements. We show that 1D analytical models are generally not suitable for assessing the thermal conductivity of such anisotropic media. Yet, a few anisotropic models can still be of interest to relate some structural parameters, like the fiber orientation distribution, to the thermal properties. Finally, our results emphasize that numerical simulations on 3D realistic microstructure is a very interesting alternative to experimental measurements.

  13. Fabrication of Conductive 3D Gold-Containing Microstructures via Direct Laser Writing.

    PubMed

    Blasco, Eva; Müller, Jonathan; Müller, Patrick; Trouillet, Vanessa; Schön, Markus; Scherer, Torsten; Barner-Kowollik, Christopher; Wegener, Martin

    2016-05-01

    3D conductive microstructures containing gold are fabricated by simultaneous photopolymerization and photoreduction via direct laser writing. The photoresist employed consists of water-soluble polymers and a gold precursor. The fabricated microstructures show good conductivity and are successfully employed for 3D connections between gold pads.

  14. 3D structure and conductive thermal field of the Upper Rhine Graben

    NASA Astrophysics Data System (ADS)

    Freymark, Jessica; Sippel, Judith; Scheck-Wenderoth, Magdalena; Bär, Kristian; Stiller, Manfred; Fritsche, Johann-Gerhard; Kracht, Matthias

    2016-04-01

    The Upper Rhine Graben (URG) was formed as part of the European Cenozoic Rift System in a complex extensional setting. At present-day, it has a large socioeconomic relevance as it provides a great potential for geothermal energy production in Germany and France. For the utilisation of this energy resource it is crucial to understand the structure and the observed temperature anomalies in the rift basin. In the framework of the EU-funded "IMAGE" project (Integrated Methods for Advanced Geothermal Exploration), we apply a data-driven numerical modelling approach to quantify the processes and properties controlling the spatial distribution of subsurface temperatures. Typically, reservoir-scale numerical models are developed for predictions on the subsurface hydrothermal conditions and for reducing the risk of drilling non-productive geothermal wells. One major problem related to such models is setting appropriate boundary conditions that define, for instance, how much heat enters the reservoir from greater depths. Therefore, we first build a regional lithospheric-scale 3D structural model, which covers not only the entire URG but also adjacent geological features like the Black Forest and the Vosges Mountains. In particular, we use a multidisciplinary dataset (e.g. well data, seismic reflection data, existing structural models, gravity) to construct the geometries of the sediments, the crust and the lithospheric mantle that control the spatial distribution of thermal conductivity and radiogenic heat production and hence temperatures. By applying a data-based and lithology-dependent parameterisation of this lithospheric-scale 3D structural model and a 3D finite element method, we calculate the steady-state conductive thermal field for the entire region. Available measured temperatures (down to depths of up to 5 km) are considered to validate the 3D thermal model. We present major characteristics of the lithospheric-scale 3D structural model and results of the 3D

  15. An Effective 3D Ear Acquisition System.

    PubMed

    Liu, Yahui; Lu, Guangming; Zhang, David

    2015-01-01

    The human ear is a new feature in biometrics that has several merits over the more common face, fingerprint and iris biometrics. It can be easily captured from a distance without a fully cooperative subject. Also, the ear has a relatively stable structure that does not change much with the age and facial expressions. In this paper, we present a novel method of 3D ear acquisition system by using triangulation imaging principle, and the experiment results show that this design is efficient and can be used for ear recognition.

  16. An Effective 3D Ear Acquisition System

    PubMed Central

    Liu, Yahui; Lu, Guangming; Zhang, David

    2015-01-01

    The human ear is a new feature in biometrics that has several merits over the more common face, fingerprint and iris biometrics. It can be easily captured from a distance without a fully cooperative subject. Also, the ear has a relatively stable structure that does not change much with the age and facial expressions. In this paper, we present a novel method of 3D ear acquisition system by using triangulation imaging principle, and the experiment results show that this design is efficient and can be used for ear recognition. PMID:26061553

  17. Restoring Fort Frontenac in 3D: Effective Usage of 3D Technology for Heritage Visualization

    NASA Astrophysics Data System (ADS)

    Yabe, M.; Goins, E.; Jackson, C.; Halbstein, D.; Foster, S.; Bazely, S.

    2015-02-01

    This paper is composed of three elements: 3D modeling, web design, and heritage visualization. The aim is to use computer graphics design to inform and create an interest in historical visualization by rebuilding Fort Frontenac using 3D modeling and interactive design. The final model will be integr ated into an interactive website to learn more about the fort's historic imp ortance. It is apparent that using computer graphics can save time and money when it comes to historical visualization. Visitors do not have to travel to the actual archaeological buildings. They can simply use the Web in their own home to learn about this information virtually. Meticulously following historical records to create a sophisticated restoration of archaeological buildings will draw viewers into visualizations, such as the historical world of Fort Frontenac. As a result, it allows the viewers to effectively understand the fort's social sy stem, habits, and historical events.

  18. Kondo behavior and conductance through 3d impurities in gold chains doped with oxygen

    NASA Astrophysics Data System (ADS)

    Barral, M. A.; Di Napoli, S.; Blesio, G.; Roura-Bas, P.; Camjayi, A.; Manuel, L. O.; Aligia, A. A.

    2017-03-01

    Combining ab initio calculations and effective models derived from them, we discuss the electronic structure of oxygen doped gold chains when one Au atom is replaced by any transition-metal atom of the 3d series. The effect of O doping is to bring extended Au 5dxz and 5dyz states to the Fermi level, which together with the Au states of zero angular momentum projection leads to three possible channels for the screening of the magnetism of the impurity. For most 3d impurities the expected physics is similar to that of the underscreened Kondo model, with singular Fermi liquid behavior. For Fe and Co under a tetragonal crystal field introduced by leads, the system might display a non-Fermi liquid behavior. Ni and Cu impurities are described by a S = 1 two channel Kondo model and an SU(4) impurity Anderson model in the intermediate valence regime, respectively. In both cases, the system is a Fermi liquid, but the conductance shows some observable differences with the ordinary SU(2) Anderson model.

  19. Compilation of 3D global conductivity model of the Earth for space weather applications

    NASA Astrophysics Data System (ADS)

    Alekseev, Dmitry; Kuvshinov, Alexey; Palshin, Nikolay

    2015-07-01

    We have compiled a global three-dimensional (3D) conductivity model of the Earth with an ultimate goal to be used for realistic simulation of geomagnetically induced currents (GIC), posing a potential threat to man-made electric systems. Bearing in mind the intrinsic frequency range of the most intense disturbances (magnetospheric substorms) with typical periods ranging from a few minutes to a few hours, the compiled 3D model represents the structure in depth range of 0-100 km, including seawater, sediments, earth crust, and partly the lithosphere/asthenosphere. More explicitly, the model consists of a series of spherical layers, whose vertical and lateral boundaries are established based on available data. To compile a model, global maps of bathymetry, sediment thickness, and upper and lower crust thicknesses as well as lithosphere thickness are utilized. All maps are re-interpolated on a common grid of 0.25×0.25 degree lateral spacing. Once the geometry of different structures is specified, each element of the structure is assigned either a certain conductivity value or conductivity versus depth distribution, according to available laboratory data and conversion laws. A numerical formalism developed for compilation of the model, allows for its further refinement by incorporation of regional 3D conductivity distributions inferred from the real electromagnetic data. So far we included into our model four regional conductivity models, available from recent publications, namely, surface conductance model of Russia, and 3D conductivity models of Fennoscandia, Australia, and northwest of the United States.

  20. 3D conductive coupling for efficient generation of prominent Fano resonances in metamaterials

    NASA Astrophysics Data System (ADS)

    Liu, Zhiguang; Liu, Zhe; Li, Jiafang; Li, Wuxia; Li, Junjie; Gu, Changzhi; Li, Zhi-Yuan

    2016-06-01

    We demonstrate a 3D conductive coupling mechanism for the efficient generation of prominent and robust Fano resonances in 3D metamaterials (MMs) formed by integrating vertical U-shape split-ring resonators (SRRs) or vertical rectangular plates along a planar metallic hole array with extraordinary optical transmission (EOT). In such a configuration, intensified vertical E-field is induced along the metallic holes and naturally excites the electric resonances of the vertical structures, which form non-radiative “dark” modes. These 3D conductive “dark” modes strongly interfere with the “bright” resonance mode of the EOT structure, generating significant Fano resonances with both prominent destructive and constructive interferences. The demonstrated 3D conductive coupling mechanism is highly universal in that both 3D MMs with vertical SRRs and vertical plates exhibit the same prominent Fano resonances despite their dramatic structural difference, which is conceptually different from conventional capacitive and inductive coupling mechanisms that degraded drastically upon small structural deviations.

  1. Precise 3D printing of micro/nanostructures using highly conductive carbon nanotube-thiol-acrylate composites

    NASA Astrophysics Data System (ADS)

    Liu, Y.; Xiong, W.; Jiang, L. J.; Zhou, Y. S.; Lu, Y. F.

    2016-04-01

    Two-photon polymerization (TPP) is of increasing interest due to its unique combination of truly three-dimensional (3D) fabrication capability and ultrahigh spatial resolution of ~40 nm. However, the stringent requirements of non-linear resins seriously limit the material functionality of 3D printing via TPP. Precise fabrication of 3D micro/nanostructures with multi-functionalities such as high electrical conductivity and mechanical strength is still a long-standing challenge. In this work, TPP fabrication of arbitrary 3D micro/nanostructures using multi-walled carbon nanotube (MWNT)-thiolacrylate (MTA) composite resins has been developed. Up to 0.2 wt% MWNTs have been incorporated into thiol-acrylate resins to form highly stable and uniform composite photoresists without obvious degradation for one week at room temperature. Various functional 3D micro/nanostructures including woodpiles, micro-coils, spiral-like photonic crystals, suspended micro-bridges, micro-gears and complex micro-cars have been successfully fabricated. The MTA composite resin offers significant enhancements in electrical conductivity and mechanical strength, and on the same time, preserving high optical transmittance and flexibility. Tightly controlled alignment of MWNTs and the strong anisotropy effect were confirmed. Microelectronic devices including capacitors and resistors made of the MTA composite polymer were demonstrated. The 3D micro/nanofabrication using the MTA composite resins enables the precise 3D printing of micro/nanostructures of high electrical conductivity and mechanical strength, which is expected to lead a wide range of device applications, including micro/nano-electromechanical systems (MEMS/NEMS), integrated photonics and 3D electronics.

  2. Stereoscopic 3D video games and their effects on engagement

    NASA Astrophysics Data System (ADS)

    Hogue, Andrew; Kapralos, Bill; Zerebecki, Chris; Tawadrous, Mina; Stanfield, Brodie; Hogue, Urszula

    2012-03-01

    With television manufacturers developing low-cost stereoscopic 3D displays, a large number of consumers will undoubtedly have access to 3D-capable televisions at home. The availability of 3D technology places the onus on content creators to develop interesting and engaging content. While the technology of stereoscopic displays and content generation are well understood, there are many questions yet to be answered surrounding its effects on the viewer. Effects of stereoscopic display on passive viewers for film are known, however video games are fundamentally different since the viewer/player is actively (rather than passively) engaged in the content. Questions of how stereoscopic viewing affects interaction mechanics have previously been studied in the context of player performance but very few have attempted to quantify the player experience to determine whether stereoscopic 3D has a positive or negative influence on their overall engagement. In this paper we present a preliminary study of the effects stereoscopic 3D have on player engagement in video games. Participants played a video game in two conditions, traditional 2D and stereoscopic 3D and their engagement was quantified using a previously validated self-reporting tool. The results suggest that S3D has a positive effect on immersion, presence, flow, and absorption.

  3. A Tunable 3D Nanostructured Conductive Gel Framework Electrode for High-Performance Lithium Ion Batteries.

    PubMed

    Shi, Ye; Zhang, Jun; Bruck, Andrea M; Zhang, Yiman; Li, Jing; Stach, Eric A; Takeuchi, Kenneth J; Marschilok, Amy C; Takeuchi, Esther S; Yu, Guihua

    2017-03-22

    This study develops a tunable 3D nanostructured conductive gel framework as both binder and conductive framework for lithium ion batteries. A 3D nanostructured gel framework with continuous electron pathways can provide hierarchical pores for ion transport and form uniform coatings on each active particle against aggregation. The hybrid gel electrodes based on a polypyrrole gel framework and Fe3 O4 nanoparticles as a model system in this study demonstrate the best rate performance, the highest achieved mass ratio of active materials, and the highest achieved specific capacities when considering total electrode mass, compared to current literature. This 3D nanostructured gel-based framework represents a powerful platform for various electrochemically active materials to enable the next-generation high-energy batteries.

  4. A Simple, Low-Cost Conductive Composite Material for 3D Printing of Electronic Sensors

    PubMed Central

    Leigh, Simon J.; Bradley, Robert J.; Purssell, Christopher P.; Billson, Duncan R.; Hutchins, David A.

    2012-01-01

    3D printing technology can produce complex objects directly from computer aided digital designs. The technology has traditionally been used by large companies to produce fit and form concept prototypes (‘rapid prototyping’) before production. In recent years however there has been a move to adopt the technology as full-scale manufacturing solution. The advent of low-cost, desktop 3D printers such as the RepRap and Fab@Home has meant a wider user base are now able to have access to desktop manufacturing platforms enabling them to produce highly customised products for personal use and sale. This uptake in usage has been coupled with a demand for printing technology and materials able to print functional elements such as electronic sensors. Here we present formulation of a simple conductive thermoplastic composite we term ‘carbomorph’ and demonstrate how it can be used in an unmodified low-cost 3D printer to print electronic sensors able to sense mechanical flexing and capacitance changes. We show how this capability can be used to produce custom sensing devices and user interface devices along with printed objects with embedded sensing capability. This advance in low-cost 3D printing with offer a new paradigm in the 3D printing field with printed sensors and electronics embedded inside 3D printed objects in a single build process without requiring complex or expensive materials incorporating additives such as carbon nanotubes. PMID:23185319

  5. Electrochemical fields within 3D reconstructed microstructures of mixed ionic and electronic conducting devices

    NASA Astrophysics Data System (ADS)

    Zhang, Yanxiang; Chen, Yu; Lin, Ye; Yan, Mufu; Harris, William M.; Chiu, Wilson K. S.; Ni, Meng; Chen, Fanglin

    2016-11-01

    The performance and stability of the mixed ionic and electronic conducting (MIEC) membrane devices, such as solid oxide cells (SOCs) and oxygen separation membranes (OSMs) interplay tightly with the transport properties and the three-dimensional (3D) microstructure of the membrane. However, development of the MIEC devices is hindered by the limited knowledge about the distribution of electrochemical fields within the 3D local microstructures, especially at surface and interface. In this work, a generic model conforming to local thermodynamic equilibrium is developed to calculate the electrochemical fields, such as electric potential and oxygen chemical potential, within the 3D microstructure of the MIEC membrane. Stability of the MIEC membrane is evaluated by the distribution of oxygen partial pressure. The cell-level performance such as polarization resistance and voltage vs. current curve can be further calculated. Case studies are performed to demonstrate the capability of the framework by using X-ray computed tomography reconstructed 3D microstructures of a SOC and an OSM. The calculation method demonstrates high computational efficiency for large size 3D tomographic microstructures, and permits parallel calculation. The framework can serve as a powerful tool for correlating the transport properties and the 3D microstructure to the performance and the stability of MIEC devices.

  6. A simple, low-cost conductive composite material for 3D printing of electronic sensors.

    PubMed

    Leigh, Simon J; Bradley, Robert J; Purssell, Christopher P; Billson, Duncan R; Hutchins, David A

    2012-01-01

    3D printing technology can produce complex objects directly from computer aided digital designs. The technology has traditionally been used by large companies to produce fit and form concept prototypes ('rapid prototyping') before production. In recent years however there has been a move to adopt the technology as full-scale manufacturing solution. The advent of low-cost, desktop 3D printers such as the RepRap and Fab@Home has meant a wider user base are now able to have access to desktop manufacturing platforms enabling them to produce highly customised products for personal use and sale. This uptake in usage has been coupled with a demand for printing technology and materials able to print functional elements such as electronic sensors. Here we present formulation of a simple conductive thermoplastic composite we term 'carbomorph' and demonstrate how it can be used in an unmodified low-cost 3D printer to print electronic sensors able to sense mechanical flexing and capacitance changes. We show how this capability can be used to produce custom sensing devices and user interface devices along with printed objects with embedded sensing capability. This advance in low-cost 3D printing with offer a new paradigm in the 3D printing field with printed sensors and electronics embedded inside 3D printed objects in a single build process without requiring complex or expensive materials incorporating additives such as carbon nanotubes.

  7. 3D fabrication of all-polymer conductive microstructures by two photon polymerization.

    PubMed

    Kurselis, Kestutis; Kiyan, Roman; Bagratashvili, Victor N; Popov, Vladimir K; Chichkov, Boris N

    2013-12-16

    A technique to fabricate electrically conductive all-polymer 3D microstructures is reported. Superior conductivity, high spatial resolution and three-dimensionality are achieved by successive application of two-photon polymerization and in situ oxidative polymerization to a bi-component formulation, containing a photosensitive host matrix and an intrinsically conductive polymer precursor. By using polyethylene glycol diacrylate (PEG-DA) and 3,4-ethylenedioxythiophene (EDOT), the conductivity of 0.04 S/cm is reached, which is the highest value for the two-photon polymerized all-polymer microstructures to date. The measured electrical conductivity dependency on the EDOT concentration indicates percolation phenomenon and a three-dimensional nature of the conductive pathways. Tunable conductivity, biocompatibility, and environmental stability are the characteristics offered by PEG-DA/EDOT blends which can be employed in biomedicine, MEMS, microfluidics, and sensorics.

  8. 3D effects on energetic particle confinement and stability

    NASA Astrophysics Data System (ADS)

    Spong, Don

    2010-11-01

    Understanding the confinement and stability of energetic particle (EP) populations in 3D magnetic configurations is crucial to the future of all toroidal devices. Tokamaks will have weak symmetry-breaking effects from discrete coils, heterogeneous distributions of ferritic materials and non-symmetric (ELM/RWM) control coils, while stellarators and helical RFP states have dominant 3D features by design. Significant EP issues for 3D systems include: modifications of the plasma equilibrium and potential amplification of field errors, asymmetry enhanced EP losses and their impact both on wall heat loads and the confined EP distribution, 3D modifications to the Alfvén gap and mode structure, and the stability properties of EP-destabilized Alfvén modes. 3D equilibria that resolve localized TBM (test blanket module) asymmetries have now been developed for DIII-D and ITER. Such symmetry breaking leads to enhanced EP losses and focused wall deposition. 3D effects also modify the Alfvén spectrum by increasing the number of possibilities for mode coupling and introducing new gap structures, including the helical and mirror gaps, fine scale ripple-induced gaps and continuum crossing gaps. Improved methods have recently been developed for evaluating these modes and their stability, taking into account the large number of coupled modes and finite orbit width effects. Successful Alfvén mode identifications have been made for a range of stellarators, including W7-AS, LHD, HSX and TJ-II. A comprehensive understanding of energetic particle physics with 3D effects is a necessary prerequisite for wall protection, plasma control and flexibility and for new diagnostic development possibilities in future ignited systems.

  9. Electromagnetic Response Inversion for a 3D Distribution of Conductivity/Dielect

    SciTech Connect

    Newman, Gregory

    2001-10-24

    NLCGCS inverts electromagnetic responses for a 3D distribution of electrical conductivity and dielectric permittivity within the earth for geophysical applications using single processor computers. The software comes bundled with a graphical user interface to aid in model construction and analysis and viewing of earth images. The solution employs both dipole and finite size source configurations for harmonic oscillatory sources. A new nonlinear preconditioner is included in the solution to speed up solution convergence.

  10. Extreme low thermal conductivity in nanoscale 3D Si phononic crystal with spherical pores.

    PubMed

    Yang, Lina; Yang, Nuo; Li, Baowen

    2014-01-01

    In this work, we propose a nanoscale three-dimensional (3D) Si phononic crystal (PnC) with spherical pores, which can reduce the thermal conductivity of bulk Si by a factor up to 10,000 times at room temperature. Thermal conductivity of Si PnCs depends on the porosity, for example, the thermal conductivity of Si PnCs with porosity 50% is 300 times smaller than that of bulk Si. The phonon participation ratio spectra demonstrate that more phonons are localized as the porosity increases. The thermal conductivity is insensitive to the temperature changes from room temperature to 1100 K. The extreme-low thermal conductivity could lead to a larger value of ZT than unity as the periodic structure affects very little the electric conductivity.

  11. Effects of 3D Virtual Reality of Plate Tectonics on Fifth Grade Students' Achievement and Attitude toward Science

    ERIC Educational Resources Information Center

    Kim, Paul

    2006-01-01

    This study examines the effects of a teaching method using 3D virtual reality simulations on achievement and attitude toward science. An experiment was conducted with fifth-grade students (N = 41) to examine the effects of 3D simulations, designed to support inquiry-based science curriculum. An ANOVA analysis revealed that the 3D group scored…

  12. Human Sinoatrial Node Structure: 3D Microanatomy of Sinoatrial Conduction Pathways

    PubMed Central

    Csepe, Thomas A.; Zhao, Jichao; Hansen, Brian J.; Li, Ning; Sul, Lidiya V.; Lim, Praise; Wang, Yufeng; Simonetti, Orlando P.; Kilic, Ahmet; Mohler, Peter J.; Janssen, Paul ML.; Fedorov, Vadim V.

    2016-01-01

    Introduction Despite a century of extensive study on the human sinoatrial node (SAN), the structure-to-function features of specialized SAN conduction pathways (SACP) are still unknown and debated. We report a new method for direct analysis of the SAN microstructure in optically-mapped human hearts with and without clinical history of SAN dysfunction. Methods Two explanted donor human hearts were coronary-perfused and optically-mapped. Structural analyses of histological sections parallel to epicardium (~13-21μm intervals) were integrated with optical maps to create 3D computational reconstructions of the SAN complex. High-resolution fiber fields were obtained using 3D Eigen-analysis of the structure tensor, and used to analyze SACP microstructure with a fiber-tracking approach. Results Optical mapping revealed normal SAN activation of the atria through a lateral SACP proximal to the crista terminalis in Heart #1 but persistent SAN exit block in diseased Heart #2. 3D structural analysis displayed a functionally-observed SAN border composed of fibrosis, fat, and/or discontinuous fibers between SAN and atria, which was only crossed by several branching myofiber tracts in SACP regions. Computational 3D fiber-tracking revealed that myofiber tracts of SACPs created continuous connections between SAN #1 and atria, but in SAN #2, SACP region myofiber tracts were discontinuous due to fibrosis and fat. Conclusions We developed a new integrative functional, structural and computational approach that allowed for the resolution of the specialized 3D microstructure of human SACPs for the first time. Application of this integrated approach will shed new light on the role of the specialized SAN microanatomy in maintaining sinus rhythm. PMID:26743207

  13. Programming standards for effective S-3D game development

    NASA Astrophysics Data System (ADS)

    Schneider, Neil; Matveev, Alexander

    2008-02-01

    When a video game is in development, more often than not it is being rendered in three dimensions - complete with volumetric depth. It's the PC monitor that is taking this three-dimensional information, and artificially displaying it in a flat, two-dimensional format. Stereoscopic drivers take the three-dimensional information captured from DirectX and OpenGL calls and properly display it with a unique left and right sided view for each eye so a proper stereoscopic 3D image can be seen by the gamer. The two-dimensional limitation of how information is displayed on screen has encouraged programming short-cuts and work-arounds that stifle this stereoscopic 3D effect, and the purpose of this guide is to outline techniques to get the best of both worlds. While the programming requirements do not significantly add to the game development time, following these guidelines will greatly enhance your customer's stereoscopic 3D experience, increase your likelihood of earning Meant to be Seen certification, and give you instant cost-free access to the industry's most valued consumer base. While this outline is mostly based on NVIDIA's programming guide and iZ3D resources, it is designed to work with all stereoscopic 3D hardware solutions and is not proprietary in any way.

  14. 3D quantum gravity and effective noncommutative quantum field theory.

    PubMed

    Freidel, Laurent; Livine, Etera R

    2006-06-09

    We show that the effective dynamics of matter fields coupled to 3D quantum gravity is described after integration over the gravitational degrees of freedom by a braided noncommutative quantum field theory symmetric under a kappa deformation of the Poincaré group.

  15. Photopolymerization of 3D conductive polypyrrole structures via digital light processing

    NASA Astrophysics Data System (ADS)

    Price, Aaron D.

    2016-04-01

    The intrinsically conductive polymer polypyrrole is conventionally synthesized as monolithic films that exhibit significant actuation strains when subjected to an applied electric potential. Though numerous linear and bending actuators based on polypyrrole films have been investigated, the limitations inherent to planar film geometries inhibit the realization of more complex behaviours. Hence, three-dimensional polypyrrole structures are sought to greatly expand the potential applications for conductive polymer actuators. This research aims to develop a novel additive manufacturing method for the fabrication of three-dimensional structures of conductive polypyrrole. In this investigation, radiation-curing techniques are employed by means of digital light processing (DLP) technology. DLP is an additive manufacturing technique where programmed light patterns emitted from a dedicated source are used to selectively cure a specially formulated polymer resin. Successive curing operations lead to a layered 3D structure into which fine features may be incorporated. Energy dispersive spectroscopy (EDS) is subsequently employed to examine the unique microstructural features of the resultant 3D printed polymer morphology in order to elucidate the nature of the conductivity. These polymer microstructures are highly desirable since actuation response times are highly dependent on ion transport distances, and hence the ability to fabricate fine features offers a potential mechanism to improve actuator performance.

  16. Modeling geomagnetic induction hazards using a 3-D electrical conductivity model of Australia

    NASA Astrophysics Data System (ADS)

    Wang, Liejun; Lewis, Andrew M.; Ogawa, Yasuo; Jones, William V.; Costelloe, Marina T.

    2016-12-01

    The surface electric field induced by external geomagnetic source fields is modeled for a continental-scale 3-D electrical conductivity model of Australia at periods of a few minutes to a few hours. The amplitude and orientation of the induced electric field at periods of 360 s and 1800 s are presented and compared to those derived from a simplified ocean-continent (OC) electrical conductivity model. It is found that the induced electric field in the Australian region is distorted by the heterogeneous continental electrical conductivity structures and surrounding oceans. On the northern coastlines, the induced electric field is decreased relative to the simple OC model due to a reduced conductivity contrast between the seas and the enhanced conductivity structures inland. In central Australia, the induced electric field is less distorted with respect to the OC model as the location is remote from the oceans, but inland crustal high-conductivity anomalies are the major source of distortion of the induced electric field. In the west of the continent, the lower conductivity of the Western Australia Craton increases the conductivity contrast between the deeper oceans and land and significantly enhances the induced electric field. Generally, the induced electric field in southern Australia, south of latitude -20°, is higher compared to northern Australia. This paper provides a regional indicator of geomagnetic induction hazards across Australia.

  17. Robotic extrusion processes for direct ink writing of 3D conductive polyaniline structures

    NASA Astrophysics Data System (ADS)

    Holness, F. Benjamin; Price, Aaron D.

    2016-04-01

    The intractable nature of intrinsically conductive polymers (ICP) leads to practical limitations in the fabrication of ICP-based transducers having complex three-dimensional geometries. Conventional ICP device fabrication processes have focused primarily on thin-film deposition techniques; therefore this study explores novel additive manufacturing processes specifically developed for ICP with the ultimate goal of increasing the functionality of ICP sensors and actuators. Herein we employ automated polymer paste extrusion processes for the direct ink writing of 3D conductive polyaniline (PANI) structures. Realization of these structures is enabled through a modified fused filament fabrication delta robot equipped with an integrated polymer paste extruder. This unique robot-controlled additive manufacturing platform is capable of fabricating high-resolution 3D conductive PANI and has been utilized to produce structures with a minimum feature size of 1.5 mm. The required processability of PANI is achieved by means of a counter-ion induced thermal doping method. Using this method, a viscous paste is formulated as the extrudate and a thermo-chemical treatment is applied post extrusion to finalize the complexation.

  18. A miniature microbial fuel cell with conducting nanofibers-based 3D porous biofilm

    NASA Astrophysics Data System (ADS)

    Jiang, Huawei; Halverson, Larry J.; Dong, Liang

    2015-12-01

    Miniature microbial fuel cell (MFC) technology has received growing interest due to its potential applications in high-throughput screening of bacteria and mutants to elucidate mechanisms of electricity generation. This paper reports a novel miniature MFC with an improved output power density and short startup time, utilizing electrospun conducting poly(3,4-ethylenedioxythiophene) (PEDOT) nanofibers as a 3D porous anode within a 12 μl anolyte chamber. This device results in 423 μW cm-3 power density based on the volume of the anolyte chamber, using Shewanella oneidensis MR-1 as a model biocatalyst without any optimization of bacterial culture. The device also excels in a startup time of only 1hr. The high conductivity of the electrospun nanofibers makes them suitable for efficient electron transfer. The mean pore size of the conducting nanofibers is several micrometers, which is favorable for bacterial penetration and colonization of surfaces of the nanofibers. We demonstrate that S. oneidensis can fully colonize the interior region of this nanofibers-based porous anode. This work represents a new attempt to explore the use of electrospun PEDOT nanofibers as a 3D anode material for MFCs. The presented miniature MFC potentially will provide a high-sensitivity, high-throughput tool to screen suitable bacterial species and mutant strains for use in large-size MFCs.

  19. THERM3D -- A boundary element computer program for transient heat conduction problems

    SciTech Connect

    Ingber, M.S.

    1994-02-01

    The computer code THERM3D implements the direct boundary element method (BEM) to solve transient heat conduction problems in arbitrary three-dimensional domains. This particular implementation of the BEM avoids performing time-consuming domain integrations by approximating a ``generalized forcing function`` in the interior of the domain with the use of radial basis functions. An approximate particular solution is then constructed, and the original problem is transformed into a sequence of Laplace problems. The code is capable of handling a large variety of boundary conditions including isothermal, specified flux, convection, radiation, and combined convection and radiation conditions. The computer code is benchmarked by comparisons with analytic and finite element results.

  20. Radiation Effects in 3D Integrated SOl SRAM Circuits

    DTIC Science & Technology

    2011-08-23

    Comparing Neutrons and Protons Data Monoenergetic neutrons and protons are used to characterize single event effects in electronics circuits, and are...for proton irradiation with energies between 4.8 and 500 MeV. Results are compared with 14-MeV neutron irradiation. Single event upset cross-section...fabricating circuits for space applications. singIe event effects, SOl, fully depleted, 3D integration, neutron , protons, upset cross-section U U U U SAR

  1. Effective 3-D surface modeling for geographic information systems

    NASA Astrophysics Data System (ADS)

    Yüksek, K.; Alparslan, M.; Mendi, E.

    2016-01-01

    In this work, we propose a dynamic, flexible and interactive urban digital terrain platform with spatial data and query processing capabilities of geographic information systems, multimedia database functionality and graphical modeling infrastructure. A new data element, called Geo-Node, which stores image, spatial data and 3-D CAD objects is developed using an efficient data structure. The system effectively handles data transfer of Geo-Nodes between main memory and secondary storage with an optimized directional replacement policy (DRP) based buffer management scheme. Polyhedron structures are used in digital surface modeling and smoothing process is performed by interpolation. The experimental results show that our framework achieves high performance and works effectively with urban scenes independent from the amount of spatial data and image size. The proposed platform may contribute to the development of various applications such as Web GIS systems based on 3-D graphics standards (e.g., X3-D and VRML) and services which integrate multi-dimensional spatial information and satellite/aerial imagery.

  2. Toward A 3-D Picture of Hydraulic Conductivity With Multilevel Slug Tests

    NASA Astrophysics Data System (ADS)

    McElwee, C. D.; McElwee, C. D.; Ross, H. C.

    2001-12-01

    The GEMS (Geohydrologic Experiment and Monitoring Site) field area has been established (in the Kansas River valley near Lawrence, Kansas) for a variety of reasons relating to research and teaching in hydrogeology at the University of Kansas. Over 70 wells have been installed for various purposes. The site overlies an alluvial aquifer with a total thickness of about 70 feet. The water table is typically about 20 feet below the surface, giving a total saturated thickness of about 50 feet. The upper part of the aquifer is finer material consisting of silt and clay. Typically, the lower 35 feet of the aquifer is sand and gravel. A number of wells through out the site are fully screened through the sand and gravel aquifer. Some of these fully screened wells are larger diameters; however, most wells are constructed of 2 inch PVC casing. Slug tests are widely used in hydrogeology to measure hydraulic conductivity. Over the last several years we have been conducting research to improve the slug test method. We have previously reported the detailed structure of hydraulic conductivity that can be seen in a 5 inch well (McElwee and Zemansky, EOS, v. 80, no. 46, p. F397, 1999) at this site, using multilevel slug tests. The existing 2 inch, fully screened wells are spread out over the site and offer the opportunity for developing a 3-D picture of the hydraulic conductivity distribution. However, it is difficult to develop a system that allows multilevel slug tests to be done accurately and efficiently in a 2 inch well. This is especially true in regions of very high hydraulic conductivity, where the water velocity in the casing will be relatively high. The resistance caused by frictional forces in the equipment must be minimized and a model taking account of these forces must be used. We have developed a system (equipment, software, and technique) for performing multilevel slug tests in 2 inch wells. Some equipment configurations work better than others. The data that we have

  3. Developmental neurotoxic effects of Malathion on 3D neurosphere system

    PubMed Central

    Salama, Mohamed; Lotfy, Ahmed; Fathy, Khaled; Makar, Maria; El-emam, Mona; El-gamal, Aya; El-gamal, Mohamed; Badawy, Ahmad; Mohamed, Wael M.Y.; Sobh, Mohamed

    2015-01-01

    Developmental neurotoxicity (DNT) refers to the toxic effects induced by various chemicals on brain during the early childhood period. As human brains are vulnerable during this period, various chemicals would have significant effects on brains during early childhood. Some toxicants have been confirmed to induce developmental toxic effects on CNS; however, most of agents cannot be identified with certainty. This is because available animal models do not cover the whole spectrum of CNS developmental periods. A novel alternative method that can overcome most of the limitations of the conventional techniques is the use of 3D neurosphere system. This in-vitro system can recapitulate many of the changes during the period of brain development making it an ideal model for predicting developmental neurotoxic effects. In the present study we verified the possible DNT of Malathion, which is one of organophosphate pesticides with suggested possible neurotoxic effects on nursing children. Three doses of Malathion (0.25 μM, 1 μM and 10 μM) were used in cultured neurospheres for a period of 14 days. Malathion was found to affect proliferation, differentiation and viability of neurospheres, these effects were positively correlated to doses and time progress. This study confirms the DNT effects of Malathion on 3D neurosphere model. Further epidemiological studies will be needed to link these results to human exposure and effects data. PMID:27054080

  4. Ice-Templated Assembly Strategy to Construct 3D Boron Nitride Nanosheet Networks in Polymer Composites for Thermal Conductivity Improvement.

    PubMed

    Zeng, Xiaoliang; Yao, Yimin; Gong, Zhengyu; Wang, Fangfang; Sun, Rong; Xu, Jianbin; Wong, Ching-Ping

    2015-12-01

    Owing to the growing heat removal issue of modern electronic devices, polymer composites with high thermal conductivity have drawn much attention in the past few years. However, a traditional method to enhance the thermal conductivity of the polymers by addition of inorganic fillers usually creates composite with not only limited thermal conductivity but also other detrimental effects due to large amount of fillers required. Here, novel polymer composites are reported by first constructing 3D boron nitride nanosheets (3D-BNNS) network using ice-templated approach and then infiltrating them with epoxy matrix. The obtained polymer composites exhibit a high thermal conductivity (2.85 W m(-1) K(-1)), a low thermal expansion coefficient (24-32 ppm K(-1)), and an increased glass transition temperature (T(g)) at relatively low BNNSs loading (9.29 vol%). These results demonstrate that this approach opens a new avenue for design and preparation of polymer composites with high thermal conductivity. The polymer composites are potentially useful in advanced electronic packaging techniques, namely, thermal interface materials, underfill materials, molding compounds, and organic substrates.

  5. 3D FEM Simulations of Drop Test Reliability on 3D-WLP: Effects of Solder Reflow Residual Stress and Molding Resin Parameters

    NASA Astrophysics Data System (ADS)

    Belhenini, Soufyane; Tougui, Abdellah; Bouchou, Abdelhake; Mohan, Ranganathan; Dosseul, Franck

    2014-01-01

    Numerous three-dimensional (3D) packaging technologies are currently used for 3D integration. 3D-wafer level package (3D-WLP) appears to be a way to keep increasing the density of the microelectronic components. The reliability of 3D components has to be evaluated on mechanical demonstrators with daisy chains before real production. Numerical modeling is acknowledged as a very efficient tool for design optimization. In this paper, 3D finite-elements calculations are carried out to analyze the effects of molding resin's mechanical properties and thickness on the 3D component's dynamic response under drop loading conditions. Residual stress generated by solder reflow is also discussed. The influences of residual stresses on the numerical estimation of the component behavior during drop loading are studied. Solder reflow residual stresses have an impact on solder plastic strain and die equivalent stress calculations. We have compared the result of two numerical drop test models. Stress-free initial conduction is introduced for the first model. Solder reflow residual stresses are considered as the initial condition for the second drop test model. Quantitative and qualitative comparisons are carried out to show the effect of residual stress in drop test calculations. For the effect of molding resin thickness on the component behavior under drop loading, the stress-free initial condition is considered. The effect of the molding resin's thickness on critical area location is discussed. The solder bump maximum plastic shear strain and the silicon die maximum equivalent stress are used as reliability criteria. Numerical submodeling techniques are used to increase calculation accuracy. Numerical results have contributed to the design optimization of the 3D-WLP component.

  6. Finite-Difference Algorithm for Simulating 3D Electromagnetic Wavefields in Conductive Media

    NASA Astrophysics Data System (ADS)

    Aldridge, D. F.; Bartel, L. C.; Knox, H. A.

    2013-12-01

    Electromagnetic (EM) wavefields are routinely used in geophysical exploration for detection and characterization of subsurface geological formations of economic interest. Recorded EM signals depend strongly on the current conductivity of geologic media. Hence, they are particularly useful for inferring fluid content of saturated porous bodies. In order to enhance understanding of field-recorded data, we are developing a numerical algorithm for simulating three-dimensional (3D) EM wave propagation and diffusion in heterogeneous conductive materials. Maxwell's equations are combined with isotropic constitutive relations to obtain a set of six, coupled, first-order partial differential equations governing the electric and magnetic vectors. An advantage of this system is that it does not contain spatial derivatives of the three medium parameters electric permittivity, magnetic permeability, and current conductivity. Numerical solution methodology consists of explicit, time-domain finite-differencing on a 3D staggered rectangular grid. Temporal and spatial FD operators have order 2 and N, where N is user-selectable. We use an artificially-large electric permittivity to maximize the FD timestep, and thus reduce execution time. For the low frequencies typically used in geophysical exploration, accuracy is not unduly compromised. Grid boundary reflections are mitigated via convolutional perfectly matched layers (C-PMLs) imposed at the six grid flanks. A shared-memory-parallel code implementation via OpenMP directives enables rapid algorithm execution on a multi-thread computational platform. Good agreement is obtained in comparisons of numerically-generated data with reference solutions. EM wavefields are sourced via point current density and magnetic dipole vectors. Spatially-extended inductive sources (current carrying wire loops) are under development. We are particularly interested in accurate representation of high-conductivity sub-grid-scale features that are common

  7. 3-D effects of polarization switching on interdigitated electroded ferroelectrics

    NASA Astrophysics Data System (ADS)

    Pisani, David M.; Lynch, C. S.

    2011-04-01

    Interdigitated electrodes are used to obtain an in-plane d33 coupling from patch actuators. Existing design tools do not take into consideration the three dimensional effects of polarization reorientation. This work presents a 3-D finite element code that utilizes a micromechancial constitutive law with full ferroelectric switching. The code is used to explore the design of interdigitated electrode devices. The results point to several parameters that are important to the design of these devices. These include electrode spacing, electrode width, specimen thickness, and specimen depth.

  8. 3D current source density imaging based on acoustoelectric effect: a simulation study using unipolar pulses

    PubMed Central

    Yang, Renhuan; Li, Xu; Liu, Jun; He, Bin

    2011-01-01

    It is of importance to image electrical activity and properties of biological tissues. Recently hybrid imaging modality combing ultrasound scanning and source imaging through the acousto-electric (AE) effect has generated considerable interest. Such modality has the potential to provide high spatial resolution current density imaging by utilizing the pressure induced AE resistivity change confined at the ultrasound focus. In this study, we investigate a novel 3-dimensional (3D) ultrasound current source density imaging (UCSDI) approach using unipolar ultrasound pulses. Utilizing specially designed unipolar ultrasound pulses and by combining AE signals associated to the local resistivity changes at the focusing point, we are able to reconstruct the 3D current density distribution with the boundary voltage measurements obtained while performing a 3D ultrasound scan. We have shown in computer simulation that using the present method, it is feasible to image with high spatial resolution an arbitrary 3D current density distribution in an inhomogeneous conductive media. PMID:21628774

  9. Parallel computing simulation of electrical excitation and conduction in the 3D human heart.

    PubMed

    Di Yu; Dongping Du; Hui Yang; Yicheng Tu

    2014-01-01

    A correctly beating heart is important to ensure adequate circulation of blood throughout the body. Normal heart rhythm is produced by the orchestrated conduction of electrical signals throughout the heart. Cardiac electrical activity is the resulted function of a series of complex biochemical-mechanical reactions, which involves transportation and bio-distribution of ionic flows through a variety of biological ion channels. Cardiac arrhythmias are caused by the direct alteration of ion channel activity that results in changes in the AP waveform. In this work, we developed a whole-heart simulation model with the use of massive parallel computing with GPGPU and OpenGL. The simulation algorithm was implemented under several different versions for the purpose of comparisons, including one conventional CPU version and two GPU versions based on Nvidia CUDA platform. OpenGL was utilized for the visualization / interaction platform because it is open source, light weight and universally supported by various operating systems. The experimental results show that the GPU-based simulation outperforms the conventional CPU-based approach and significantly improves the speed of simulation. By adopting modern computer architecture, this present investigation enables real-time simulation and visualization of electrical excitation and conduction in the large and complicated 3D geometry of a real-world human heart.

  10. The Effect Of 3D Audio And Other Audio Techniques On Virtual Reality Experience.

    PubMed

    Brinkman, Willem-Paul; Hoekstra, Allart R D; van Egmond, René

    2015-01-01

    Three studies were conducted to examine the effect of audio on people's experience in a virtual world. The first study showed that people could distinguish between mono, stereo, Dolby surround and 3D audio of a wasp. The second study found significant effects for audio techniques on people's self-reported anxiety, presence, and spatial perception. The third study found that adding sound to a visual virtual world had a significant effect on people's experience (including heart rate), while it found no difference in experience between stereo and 3D audio.

  11. Regional conductivity structure of Cascadia from 3D inversion of USArray magnetotelluric data

    NASA Astrophysics Data System (ADS)

    Egbert, G. D.; Patro, P. K.

    2008-12-01

    Magnetotelluric (MT) data are being acquired in a series of temporary arrays deployed across the continental US through EMScope, a part of the USArray component of EarthScope. Initial deployments in 2006 and 2007 acquired data at 110 sites covering the US Pacific Northwest. The MT sites, distributed with the same nominal spacing as the USArray seismic transportable array (~75 km), produced data in the period range 10- 20,000s of very good to excellent quality. The most striking and robust feature revealed by 3D inversion of this dataset is an extensive lower crustal conductor covering most of the study area southeast of a line running from the California border at the coast to the Blue Mountains of Northeastern Oregon. The conductance of this layer, which is about 15 km thick with a top at roughly 20 km depth, exceeds 3000 S beneath the he Northwest Basin and Range (BR) province of southeastern Oregon. The high conductivity in this region is inferred to result from fluids - including possibly partial melt at depth - associated with magmatic underplating and BR extension. The lower crust is much more resistive beneath the Coast Range, Willamette Valley and Puget Lowlands of Western Washington and Oregon, and beneath the Columbia Plateau. This area of resistive crust, which was derived from a large fragment of thickened oceanic lithosphere that was accreted to North America at approximately 48 Ma ("Siletzia"), is revealed by geological and geodetic studies to be strong, accommodating tectonic stresses through rigid block rotations. In contrast, the area to the southeast characterized by high conductivity in the lower crust is actively deforming, consistent with an important role for fluids in weakening of continental crust. The resistive Siletzia crust is broken by an elongated N-S zone of high conductivity beneath the Cascade volcanoes. High conductivities beneath the volcanoes also most likely reflect the presence of interconnected fluids, in this case released

  12. The Effects of 3D Computer Simulation on Biology Students' Achievement and Memory Retention

    ERIC Educational Resources Information Center

    Elangovan, Tavasuria; Ismail, Zurida

    2014-01-01

    A quasi experimental study was conducted for six weeks to determine the effectiveness of two different 3D computer simulation based teaching methods, that is, realistic simulation and non-realistic simulation on Form Four Biology students' achievement and memory retention in Perak, Malaysia. A sample of 136 Form Four Biology students in Perak,…

  13. New Global 3D Upper to Mid-mantle Electrical Conductivity Model Based on Observatory Data with Realistic Auroral Sources

    NASA Astrophysics Data System (ADS)

    Kelbert, A.; Egbert, G. D.; Sun, J.

    2011-12-01

    Poleward of 45-50 degrees (geomagnetic) observatory data are influenced significantly by auroral ionospheric current systems, invalidating the simplifying zonal dipole source assumption traditionally used for long period (T > 2 days) geomagnetic induction studies. Previous efforts to use these data to obtain the global electrical conductivity distribution in Earth's mantle have omitted high-latitude sites (further thinning an already sparse dataset) and/or corrected the affected transfer functions using a highly simplified model of auroral source currents. Although these strategies are partly effective, there remain clear suggestions of source contamination in most recent 3D inverse solutions - specifically, bands of conductive features are found near auroral latitudes. We report on a new approach to this problem, based on adjusting both external field structure and 3D Earth conductivity to fit observatory data. As an initial step towards full joint inversion we are using a two step procedure. In the first stage, we adopt a simplified conductivity model, with a thin-sheet of variable conductance (to represent the oceans) overlying a 1D Earth, to invert observed magnetic fields for external source spatial structure. Input data for this inversion are obtained from frequency domain principal components (PC) analysis of geomagnetic observatory hourly mean values. To make this (essentially linear) inverse problem well-posed we regularize using covariances for source field structure that are consistent with well-established properties of auroral ionospheric (and magnetospheric) current systems, and basic physics of the EM fields. In the second stage, we use a 3D finite difference inversion code, with source fields estimated from the first stage, to further fit the observatory PC modes. We incorporate higher latitude data into the inversion, and maximize the amount of available information by directly inverting the magnetic field components of the PC modes, instead of

  14. Spin-dependent Peltier effect in 3D topological insulators

    NASA Astrophysics Data System (ADS)

    Sengupta, Parijat; Kubis, Tillmann; Povolotskyi, Michael; Klimeck, Gerhard

    2013-03-01

    The Peltier effect represents the heat carrying capacity of a certain material when current passes through it. When two materials with different Peltier coefficients are placed together, the Peltier effect causes heat to flow either towards or away from the interface between them. This work utilizes the spin-polarized property of 3D topological insulator (TI) surface states to describe the transport of heat through the spin-up and spin-down channels. It has been observed that the spin channels are able to carry heat independently of each other. Spin currents can therefore be employed to supply or extract heat from an interface between materials with spin-dependent Peltier coefficients. The device is composed of a thin film of Bi2Se3 sandwiched between two layers of Bi2Te3. The thin film of Bi2Se3serves both as a normal and topological insulator. It is a normal insulator when its surfaces overlap to produce a finite band-gap. Using an external gate, Bi2Se3 film can be again tuned in to a TI. Sufficiently thick Bi2Te3 always retain TI behavior. Spin-dependent Peltier coefficients are obtained and the spin Nernst effect in TIs is shown by controlling the temperature gradient to convert charge current to spin current.

  15. A novel 3D sandwich structure of hybrid graphite nanosheets and silver nanowires as fillers for improved thermal conductivity

    NASA Astrophysics Data System (ADS)

    Zhuang, Xiao; Zhou, Yongcun; Liu, Feng

    2017-01-01

    We explored a novel 3D sandwich structure of fillers in the polymer matrix to enhance thermal conductivity. A variety of fillers in the polymer matrix play a significant role in the physical properties of the composite. Fillers containing particle and line structures are popular, and enhance the thermal and electrical conductivities. Therefore, filler-based matrix network improves conductivity. We propose a sandwich structure consisting of hybrid graphite nanosheets (two dimensions), and silver nanowires (AgNWs) (one dimension), to create a 3D sandwich structure of polyimide matrix with improved thermal conductivity. Surface treatment of graphite and silver nanowires were conducted to reduce the dielectric constant of the composite. We designed the filler of 20 wt% resulting in a high thermal conductivity of 3.21 W m‑1 K‑1 with 15% C@SiO2 and 5% AgNWs@SiO2 filler loading. The novel combination and structure markedly enhanced the thermal conductivity of the composite.

  16. Spherical 3D photonic crystal with conducting nanoshell and particle core

    NASA Astrophysics Data System (ADS)

    Zamudio-Lara, A.; Sánchez-Mondragón, J.; Escobedo-Alatorre, J.; Pérez-Careta, E.; Torres-Cisneros, M.; Tecpoyotl-Torres, Margarita; Vázquez-Buenos Aires, O.

    2009-06-01

    We discuss a structured 3D Dielectric Photonic Crystal with both a metallic core and a metallic shell. We discuss the role of each one, the stack, the core as well as the cavity formed between the core and the shell. The low frequency metallic core features becomes much more significant as it gets smaller and get diluted by the cavity.

  17. The effects of 3-D shaping on ITG stability

    NASA Astrophysics Data System (ADS)

    Rorvig, Mordechai; Hegna, Chris

    2012-03-01

    In this work we seek to understand how 3-D shaping can be used to improve ion temperature gradient stability. Part of the difficulty in deducing the role of 3-D shaping is the generation of 3-D MHD equilibria necessary for the calculations. In this work, MHD equilibrium surfaces are generated using local 3-D magnetostatic equilibrium theory [1]. We distinguish three different types of toroidal magnetic surface shaping: axisymmetric shaping, toroidal rotation of the cross section, and toroidal translation of the magnetic axis. We study these types of shaping independently and in combination to look for improvements. Linear growth rates for ITG modes are calculated using the gyrokinetics code GENE [2]. The geometric interface package GIST [3] accepts the equilibrium input data from the local equilibrium calculation. Growth rates for both axisymmetric and 3-D equilibrium calculations are presented. [4pt] [1] C. C. Hegna, Physics of Plasmas 7, 3921 (2000).[0pt] [2] F. Jenko, W. Dorland, M. Kotschenreuther, and B. N. Rogers, Physical Review Letters 7, 1904 (2000).[0pt] [3] P. Xanthopoulos, W. A. Cooper, F. Jenko, Yu. Turkin, A. Runov, and J. Geiger, Physics of Plasmas 16, 082303 (2009).

  18. Electrical conductivity of nanocomposites based on carbon nanotubes: a 3D multiscale modeling approach

    NASA Astrophysics Data System (ADS)

    Grabowski, Krzysztof; Zbyrad, Paulina; Staszewski, Wieslaw J.; Uhl, Tadeusz; Wiatr, Kazimierz; Packo, Pawel

    2016-04-01

    Remarkable electrical properties of carbon nanotubes (CNT) have lead to increased interest in studying CNT- based devices. Many of current researches are devoted to using all kinds of carbon nanomaterials in the con- struction of sensory elements. One of the most common applications is the development of high performance, large scale sensors. Due to the remarkable conductivity of CNT's such devices represent very high sensitivity. However, there are no sufficient tools for studying and designing such sensors. The main objective of this paper is to develop and validate a multiscale numerical model for a carbon nanotubes based sensor. The device utilises the change of electrical conductivity of a nanocomposite material under applied deformation. The nanocomposite consists of a number of CNTs dispersed in polymer matrix. The paper is devoted to the analysis of the impact of spatial distribution of carbon nanotubes in polymer matrix on electrical conductivity of the sensor. One of key elements is also to examine the impact of strain on electric charge ow in such anisotropic composite structures. In the following work a multiscale electro-mechanical model for CNT - based nanocomposites is proposed. The model comprises of two length scales, namely the meso- and the macro-scale for mechanical and electrical domains. The approach allows for evaluation of macro-scale mechanical response of a strain sensor. Electrical properties of polymeric material with certain CNT fractions were derived considering electrical properties of CNTs, their contact and the tunnelling effect.

  19. Flexible, solid-state, ion-conducting membrane with 3D garnet nanofiber networks for lithium batteries.

    PubMed

    Fu, Kun Kelvin; Gong, Yunhui; Dai, Jiaqi; Gong, Amy; Han, Xiaogang; Yao, Yonggang; Wang, Chengwei; Wang, Yibo; Chen, Yanan; Yan, Chaoyi; Li, Yiju; Wachsman, Eric D; Hu, Liangbing

    2016-06-28

    Beyond state-of-the-art lithium-ion battery (LIB) technology with metallic lithium anodes to replace conventional ion intercalation anode materials is highly desirable because of lithium's highest specific capacity (3,860 mA/g) and lowest negative electrochemical potential (∼3.040 V vs. the standard hydrogen electrode). In this work, we report for the first time, to our knowledge, a 3D lithium-ion-conducting ceramic network based on garnet-type Li6.4La3Zr2Al0.2O12 (LLZO) lithium-ion conductor to provide continuous Li(+) transfer channels in a polyethylene oxide (PEO)-based composite. This composite structure further provides structural reinforcement to enhance the mechanical properties of the polymer matrix. The flexible solid-state electrolyte composite membrane exhibited an ionic conductivity of 2.5 × 10(-4) S/cm at room temperature. The membrane can effectively block dendrites in a symmetric Li | electrolyte | Li cell during repeated lithium stripping/plating at room temperature, with a current density of 0.2 mA/cm(2) for around 500 h and a current density of 0.5 mA/cm(2) for over 300 h. These results provide an all solid ion-conducting membrane that can be applied to flexible LIBs and other electrochemical energy storage systems, such as lithium-sulfur batteries.

  20. Flexible, solid-state, ion-conducting membrane with 3D garnet nanofiber networks for lithium batteries

    NASA Astrophysics Data System (ADS)

    Kun, Kelvin; Gong, Yunhui; Dai, Jiaqi; Gong, Amy; Han, Xiaogang; Yao, Yonggang; Wang, Chengwei; Wang, Yibo; Chen, Yanan; Yan, Chaoyi; Li, Yiju; Wachsman, Eric D.; Hu, Liangbing

    2016-06-01

    Beyond state-of-the-art lithium-ion battery (LIB) technology with metallic lithium anodes to replace conventional ion intercalation anode materials is highly desirable because of lithium's highest specific capacity (3,860 mA/g) and lowest negative electrochemical potential (˜3.040 V vs. the standard hydrogen electrode). In this work, we report for the first time, to our knowledge, a 3D lithium-ion-conducting ceramic network based on garnet-type Li6.4La3Zr2Al0.2O12 (LLZO) lithium-ion conductor to provide continuous Li+ transfer channels in a polyethylene oxide (PEO)-based composite. This composite structure further provides structural reinforcement to enhance the mechanical properties of the polymer matrix. The flexible solid-state electrolyte composite membrane exhibited an ionic conductivity of 2.5 × 10-4 S/cm at room temperature. The membrane can effectively block dendrites in a symmetric Li | electrolyte | Li cell during repeated lithium stripping/plating at room temperature, with a current density of 0.2 mA/cm2 for around 500 h and a current density of 0.5 mA/cm2 for over 300 h. These results provide an all solid ion-conducting membrane that can be applied to flexible LIBs and other electrochemical energy storage systems, such as lithium-sulfur batteries.

  1. Flexible, solid-state, ion-conducting membrane with 3D garnet nanofiber networks for lithium batteries

    PubMed Central

    Fu, Kun (Kelvin); Gong, Yunhui; Dai, Jiaqi; Gong, Amy; Han, Xiaogang; Yao, Yonggang; Wang, Chengwei; Wang, Yibo; Chen, Yanan; Yan, Chaoyi; Li, Yiju; Wachsman, Eric D.; Hu, Liangbing

    2016-01-01

    Beyond state-of-the-art lithium-ion battery (LIB) technology with metallic lithium anodes to replace conventional ion intercalation anode materials is highly desirable because of lithium’s highest specific capacity (3,860 mA/g) and lowest negative electrochemical potential (∼3.040 V vs. the standard hydrogen electrode). In this work, we report for the first time, to our knowledge, a 3D lithium-ion–conducting ceramic network based on garnet-type Li6.4La3Zr2Al0.2O12 (LLZO) lithium-ion conductor to provide continuous Li+ transfer channels in a polyethylene oxide (PEO)-based composite. This composite structure further provides structural reinforcement to enhance the mechanical properties of the polymer matrix. The flexible solid-state electrolyte composite membrane exhibited an ionic conductivity of 2.5 × 10−4 S/cm at room temperature. The membrane can effectively block dendrites in a symmetric Li | electrolyte | Li cell during repeated lithium stripping/plating at room temperature, with a current density of 0.2 mA/cm2 for around 500 h and a current density of 0.5 mA/cm2 for over 300 h. These results provide an all solid ion-conducting membrane that can be applied to flexible LIBs and other electrochemical energy storage systems, such as lithium–sulfur batteries. PMID:27307440

  2. 3D modelling of near-surface, environmental effects on AEM data

    NASA Astrophysics Data System (ADS)

    Beamish, David

    2004-11-01

    application of such derivatives to both regional- and local-scale survey data is presented.. The special case of a near-surface, metallic pipeline has been modelled. The problem constitutes an inductive limit (current gathering) response in which the perturbation is largely confined to the in-phase coupling ratios. The main perturbations, in data and conductivity models, are within about 40 m of each side of the pipeline. The maximum perturbation to the conductivity model is only a factor of 1.5 above background. Detailed survey data across a former compact landfill (about 100×100 m) are used to compare the model behaviour predicted by the 3D modelling with survey results. The survey, conducted at two separate altitudes, provides a demonstration of 3D effects on 1D survey models as a function of frequency and elevation. Although the nature of the landfill materials and their location are not known precisely, the mapping information appears realistic.

  3. Effects of Presence, Copresence, and Flow on Learning Outcomes in 3D Learning Spaces

    ERIC Educational Resources Information Center

    Hassell, Martin D.; Goyal, Sandeep; Limayem, Moez; Boughzala, Imed

    2012-01-01

    The level of satisfaction and effectiveness of 3D virtual learning environments were examined. Additionally, 3D virtual learning environments were compared with face-to-face learning environments. Students that experienced higher levels of flow and presence also experienced more satisfaction but not necessarily more effectiveness with 3D virtual…

  4. Conducting a 3D Converted Shear Wave Project to Reduce Exploration Risk at Wister, CA

    SciTech Connect

    Matlick, Skip; Walsh, Patrick; Rhodes, Greg; Fercho, Steven

    2015-06-30

    Ormat sited 2 full-size exploration wells based on 3D seismic interpretation of fractures, prior drilling results, and temperature anomaly. The wells indicated commercial temperatures (>300 F), but almost no permeability, despite one of the wells being drilled within 820 ft of an older exploration well with reported indications of permeability. Following completion of the second well in 2012, Ormat undertook a lengthy program to 1) evaluate the lack of observed permeability, 2) estimate the likelihood of finding permeability with additional drilling, and 3) estimate resource size based on an anticipated extent of permeability.

  5. Solar carbon monoxide: poster child for 3D effects .

    NASA Astrophysics Data System (ADS)

    Ayres, T. R.; Lyons, J. R.; Ludwig, H.-G.; Caffau, E.; Wedemeyer-Böhm, S.

    Photospheric infrared (2-6 mu m) rovibrational bands of carbon monoxide (CO) provide a tough test for 3D convection models such as those calculated using CO5BOLD. The molecular formation is highly temperature-sensitive, and thus responds in an exaggerated way to thermal fluctuations in the dynamic atmosphere. CO, itself, is an important tracer of the oxygen abundance, a still controversial issue in solar physics; as well as the heavy isotopes of carbon (13C) and oxygen (18O, 17O), which, relative to terrestrial values, are fingerprints of fractionation processes that operated in the primitive solar nebula. We show how 3D models impact the CO line formation, and add in a second constraint involving the near-UV Ca RIPTSIZE II line wings, which also are highly temperature sensitive, but in the opposite sense to the molecules. We find that our reference CO5BOLD snapshots appear to be slightly too cool on average in the outer layers of the photosphere where the CO absorptions and Ca RIPTSIZE II wing emissions arise. We show, further, that previous 1D modeling was systematically biased toward higher oxygen abundances and lower isotopic ratios (e.g., R23equiv 12C/13C), suggesting an isotopically ``heavy'' Sun contrary to direct capture measurements of solar wind light ions by the Genesis Discovery Mission. New 3D ratios for the oxygen isotopes are much closer to those reported by Genesis, and the associated oxygen abundance from CO now is consistent with the recent Caffau et al. study of atomic oxygen. Some lingering discrepancies perhaps can be explained by magnetic bright points. Solar CO demonstrates graphically the wide gulf that can occur between a 3D analysis and 1D.

  6. Analysis of 3-D Propagation Effects Due to Environmental Variability

    DTIC Science & Technology

    2014-09-30

    presence of 3-D environmental variations, especially shelf break canyons . Work was also performed in support of 2-D propagation in shallow water to...propagation in the Monterey Bay Canyon . This was motivated by observations of highly variable directional features in measured acoustic vector data...Rev. 8-98) Prescribed by ANSI Std Z39-18 2 the Monterey Bay Canyon were used as inputs to the model, and broadband calculations were performed

  7. Giant Faraday effect due to Pauli exclusion principle in 3D topological insulators.

    PubMed

    Paudel, Hari P; Leuenberger, Michael N

    2014-02-26

    Experiments using ARPES, which is based on the photoelectric effect, show that the surface states in 3D topological insulators (TI) are helical. Here we consider Weyl interface fermions due to band inversion in narrow-bandgap semiconductors, such as Pb1-xSnxTe. The positive and negative energy solutions can be identified by means of opposite helicity in terms of the spin helicity operator in 3D TI as ĥ(TI) = (1/ |p|_ |) β (σ|_ x p|_ ) · z^, where β is a Dirac matrix and z^ points perpendicular to the interface. Using the 3D Dirac equation and bandstructure calculations we show that the transitions between positive and negative energy solutions, giving rise to electron-hole pairs, obey strict optical selection rules. In order to demonstrate the consequences of these selection rules, we consider the Faraday effect due to the Pauli exclusion principle in a pump-probe setup using a 3D TI double interface of a PbTe/Pb₀.₃₁Sn₀.₆₉Te/PbTe heterostructure. For that we calculate the optical conductivity tensor of this heterostructure, which we use to solve Maxwell's equations. The Faraday rotation angle exhibits oscillations as a function of probe wavelength and thickness of the heterostructure. The maxima in the Faraday rotation angle are of the order of mrds.

  8. Effective classification of 3D image data using partitioning methods

    NASA Astrophysics Data System (ADS)

    Megalooikonomou, Vasileios; Pokrajac, Dragoljub; Lazarevic, Aleksandar; Obradovic, Zoran

    2002-03-01

    We propose partitioning-based methods to facilitate the classification of 3-D binary image data sets of regions of interest (ROIs) with highly non-uniform distributions. The first method is based on recursive dynamic partitioning of a 3-D volume into a number of 3-D hyper-rectangles. For each hyper-rectangle, we consider, as a potential attribute, the number of voxels (volume elements) that belong to ROIs. A hyper-rectangle is partitioned only if the corresponding attribute does not have high discriminative power, determined by statistical tests, but it is still sufficiently large for further splitting. The final discriminative hyper-rectangles form new attributes that are further employed in neural network classification models. The second method is based on maximum likelihood employing non-spatial (k-means) and spatial DBSCAN clustering algorithms to estimate the parameters of the underlying distributions. The proposed methods were experimentally evaluated on mixtures of Gaussian distributions, on realistic lesion-deficit data generated by a simulator conforming to a clinical study, and on synthetic fractal data. Both proposed methods have provided good classification on Gaussian mixtures and on realistic data. However, the experimental results on fractal data indicated that the clustering-based methods were only slightly better than random guess, while the recursive partitioning provided significantly better classification accuracy.

  9. 3D simulation of coaxial carbon nanotube field effect transistor

    NASA Astrophysics Data System (ADS)

    Hien, Dinh Sy; Thi Luong, Nguyen; Tuan, Thi Tran Anh; Viet Nga, Dinh

    2009-09-01

    We provide a model of coaxial CNTFET geometry. Coaxial devices are of special interest because their geometry allows for better electrostatics. We explore the possibilities of using non-equilibrium Green's function method to get I-V characteristics for CNTFETs. This simulator also includes a graphic user interface (GUI) of Matlab. We review the capabilities of the simulator, and give examples of typical CNTFET's 3D simulations (current-voltage characteristics are a function of parameters such as the length of CNTFET, gate thickness and temperature). The obtained I-V characteristics of the CNTFET are also presented by analytical equations.

  10. Special effects used in creating 3D animated scenes-part 1

    NASA Astrophysics Data System (ADS)

    Avramescu, A. M.

    2015-11-01

    In present, with the help of computer, we can create special effects that look so real that we almost don't perceive them as being different. These special effects are somehow hard to differentiate from the real elements like those on the screen. With the increasingly accesible 3D field that has more and more areas of application, the 3D technology goes easily from architecture to product designing. Real like 3D animations are used as means of learning, for multimedia presentations of big global corporations, for special effects and even for virtual actors in movies. Technology, as part of the movie art, is considered a prerequisite but the cinematography is the first art that had to wait for the correct intersection of technological development, innovation and human vision in order to attain full achievement. Increasingly more often, the majority of industries is using 3D sequences (three dimensional). 3D represented graphics, commercials and special effects from movies are all designed in 3D. The key for attaining real visual effects is to successfully combine various distinct elements: characters, objects, images and video scenes; like all these elements represent a whole that works in perfect harmony. This article aims to exhibit a game design from these days. Considering the advanced technology and futuristic vision of designers, nowadays we have different and multifarious game models. Special effects are decisively contributing in the creation of a realistic three-dimensional scene. These effects are essential for transmitting the emotional state of the scene. Creating the special effects is a work of finesse in order to achieve high quality scenes. Special effects can be used to get the attention of the onlooker on an object from a scene. Out of the conducted study, the best-selling game of the year 2010 was Call of Duty: Modern Warfare 2. This way, the article aims for the presented scene to be similar with many locations from this type of games, more

  11. Versatile Method for Producing 2D and 3D Conductive Biomaterial Composites Using Sequential Chemical and Electrochemical Polymerization.

    PubMed

    Severt, Sean Y; Ostrovsky-Snider, Nicholas A; Leger, Janelle M; Murphy, Amanda R

    2015-11-18

    Flexible and conductive biocompatible materials are attractive candidates for a wide range of biomedical applications including implantable electrodes, tissue engineering, and controlled drug delivery. Here, we demonstrate that chemical and electrochemical polymerization techniques can be combined to create highly versatile silk-conducting polymer (silk-CP) composites with enhanced conductivity and electrochemical stability. Interpenetrating silk-CP composites were first generated via in situ deposition of polypyrrole during chemical polymerization of pyrrole. These composites were sufficiently conductive to serve as working electrodes for electropolymerization, which allowed an additional layer of CP to be deposited on the surface. This sequential method was applied to both 2D films and 3D sponge-like silk scaffolds, producing conductive materials with biomimetic architectures. Overall, this two-step technique expanded the range of available polymers and dopants suitable for the synthesis of mechanically robust, biocompatible, and highly conductive silk-based materials.

  12. The agreement between 3D, standard 2D and triplane 2D speckle tracking: effects of image quality and 3D volume rate.

    PubMed

    Trache, Tudor; Stöbe, Stephan; Tarr, Adrienn; Pfeiffer, Dietrich; Hagendorff, Andreas

    2014-12-01

    Comparison of 3D and 2D speckle tracking performed on standard 2D and triplane 2D datasets of normal and pathological left ventricular (LV) wall-motion patterns with a focus on the effect that 3D volume rate (3DVR), image quality and tracking artifacts have on the agreement between 2D and 3D speckle tracking. 37 patients with normal LV function and 18 patients with ischaemic wall-motion abnormalities underwent 2D and 3D echocardiography, followed by offline speckle tracking measurements. The values of 3D global, regional and segmental strain were compared with the standard 2D and triplane 2D strain values. Correlation analysis with the LV ejection fraction (LVEF) was also performed. The 3D and 2D global strain values correlated good in both normally and abnormally contracting hearts, though systematic differences between the two methods were observed. Of the 3D strain parameters, the area strain showed the best correlation with the LVEF. The numerical agreement of 3D and 2D analyses varied significantly with the volume rate and image quality of the 3D datasets. The highest correlation between 2D and 3D peak systolic strain values was found between 3D area and standard 2D longitudinal strain. Regional wall-motion abnormalities were similarly detected by 2D and 3D speckle tracking. 2DST of triplane datasets showed similar results to those of conventional 2D datasets. 2D and 3D speckle tracking similarly detect normal and pathological wall-motion patterns. Limited image quality has a significant impact on the agreement between 3D and 2D numerical strain values.

  13. Viewing 3D TV over two months produces no discernible effects on balance, coordination or eyesight

    PubMed Central

    Read, Jenny C.A.; Godfrey, Alan; Bohr, Iwo; Simonotto, Jennifer; Galna, Brook; Smulders, Tom V.

    2016-01-01

    Abstract With the rise in stereoscopic 3D media, there has been concern that viewing stereoscopic 3D (S3D) content could have long-term adverse effects, but little data are available. In the first study to address this, 28 households who did not currently own a 3D TV were given a new TV set, either S3D or 2D. The 116 members of these households all underwent tests of balance, coordination and eyesight, both before they received their new TV set, and after they had owned it for 2 months. We did not detect any changes which appeared to be associated with viewing 3D TV. We conclude that viewing 3D TV does not produce detectable effects on balance, coordination or eyesight over the timescale studied. Practitioner Summary: Concern has been expressed over possible long-term effects of stereoscopic 3D (S3D). We looked for any changes in vision, balance and coordination associated with normal home S3D TV viewing in the 2 months after first acquiring a 3D TV. We find no evidence of any changes over this timescale. PMID:26758965

  14. Viewing 3D TV over two months produces no discernible effects on balance, coordination or eyesight.

    PubMed

    Read, Jenny C A; Godfrey, Alan; Bohr, Iwo; Simonotto, Jennifer; Galna, Brook; Smulders, Tom V

    2016-08-01

    With the rise in stereoscopic 3D media, there has been concern that viewing stereoscopic 3D (S3D) content could have long-term adverse effects, but little data are available. In the first study to address this, 28 households who did not currently own a 3D TV were given a new TV set, either S3D or 2D. The 116 members of these households all underwent tests of balance, coordination and eyesight, both before they received their new TV set, and after they had owned it for 2 months. We did not detect any changes which appeared to be associated with viewing 3D TV. We conclude that viewing 3D TV does not produce detectable effects on balance, coordination or eyesight over the timescale studied. Practitioner Summary: Concern has been expressed over possible long-term effects of stereoscopic 3D (S3D). We looked for any changes in vision, balance and coordination associated with normal home S3D TV viewing in the 2 months after first acquiring a 3D TV. We find no evidence of any changes over this timescale.

  15. Effects of electromagnetic field frequencies on chondrocytes in 3D cell-printed composite constructs.

    PubMed

    Yi, Hee-Gyeong; Kang, Kyung Shin; Hong, Jung Min; Jang, Jinah; Park, Moon Nyeo; Jeong, Young Hun; Cho, Dong-Woo

    2016-07-01

    In cartilage tissue engineering, electromagnetic field (EMF) therapy has been reported to have a modest effect on promoting cartilage regeneration. However, these studies were conducted using different frequencies of EMF to stimulate chondrocytes. Thus, it is necessary to investigate the effect of EMF frequency on cartilage formation. In addition to the stimulation, a scaffold is required to satisfy the characteristics of cartilage such as its hydrated and dense extracellular matrix, and a mechanical resilience to applied loads. Therefore, we 3D-printed a composite construct composed of a polymeric framework and a chondrocyte-laden hydrogel. Here, we observed frequency-dependent positive and negative effects on chondrogenesis using a 3D cell-printed cartilage tissue. We found that a frequency of 45 Hz promoted gene expression and secretion of extracellular matrix molecules of chondrocytes. In contrast, a frequency of 7.5 Hz suppressed chondrogenic differentiation in vitro. Additionally, the EMF-treated composite constructs prior to implantation showed consistent results with those of in vitro, suggesting that in vitro pre-treatment with different EMF frequencies provides different capabilities for the enhancement of cartilage formation in vivo. This correlation between EMF frequency and 3D-printed chondrocytes suggests the necessity for optimization of EMF parameters when this physical stimulus is applied to engineered cartilage. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 1797-1804, 2016.

  16. 3D-hybrid material design with electron/lithium-ion dual-conductivity for high-performance Li-sulfur batteries

    NASA Astrophysics Data System (ADS)

    Zhao, Yan; Tan, Rui; Yang, Jie; Wang, Kai; Gao, Rongtan; Liu, Dong; Liu, Yidong; Yang, Jinlong; Pan, Feng

    2017-02-01

    We report a novel 3D-hybrid cathode material with three-dimensional (3D) N-GO/CNT framework to load sulfur (77.6 wt %), and sulfonated polyaniline (SPANI) of coating layer. Used as a cathode material, it possesses a high capacity (1196 mAh g-1@0.3 A g-1@1.6 mg cm-2), excellent charging-discharging rate (680 mAh g-1@7.5 A g-1) and long-life performance (maintaining 71.1% capacity over 450 cycles), which is mainly attributed to the benefits of excellent electronic/Li-ionic dual-conductivity and confinement effect of the 3D-hybrid N-GO/CNT framework coated by self-doping conducting polymer SPANI. Thus, a 3D sulfur cathode modified with electronic/Li-ionic dual-conduction network can significantly enhance the electrochemical performance and stability, and this novel type of material is very promising for commercial applications that require high energy and power density, long life, and excellent abuse tolerance.

  17. Inversion of multi-frequency electromagnetic induction data for 3D characterization of hydraulic conductivity

    USGS Publications Warehouse

    Brosten, T.R.; Day-Lewis, F. D.; Schultz, G.M.; Curtis, G.P.; Lane, J.W.

    2011-01-01

    Electromagnetic induction (EMI) instruments provide rapid, noninvasive, and spatially dense data for characterization of soil and groundwater properties. Data from multi-frequency EMI tools can be inverted to provide quantitative electrical conductivity estimates as a function of depth. In this study, multi-frequency EMI data collected across an abandoned uranium mill site near Naturita, Colorado, USA, are inverted to produce vertical distribution of electrical conductivity (EC) across the site. The relation between measured apparent electrical conductivity (ECa) and hydraulic conductivity (K) is weak (correlation coefficient of 0.20), whereas the correlation between the depth dependent EC obtained from the inversions, and K is sufficiently strong to be used for hydrologic estimation (correlation coefficient of -0.62). Depth-specific EC values were correlated with co-located K measurements to develop a site-specific ln(EC)-ln(K) relation. This petrophysical relation was applied to produce a spatially detailed map of K across the study area. A synthetic example based on ECa values at the site was used to assess model resolution and correlation loss given variations in depth and/or measurement error. Results from synthetic modeling indicate that optimum correlation with K occurs at ~0.5m followed by a gradual correlation loss of 90% at 2.3m. These results are consistent with an analysis of depth of investigation (DOI) given the range of frequencies, transmitter-receiver separation, and measurement errors for the field data. DOIs were estimated at 2.0??0.5m depending on the soil conductivities. A 4-layer model, with varying thicknesses, was used to invert the ECa to maximize available information within the aquifer region for improved correlations with K. Results show improved correlation between K and the corresponding inverted EC at similar depths, underscoring the importance of inversion in using multi-frequency EMI data for hydrologic estimation. ?? 2011.

  18. Slat Cove Unsteadiness Effect of 3D Flow Structures

    NASA Technical Reports Server (NTRS)

    Choudhari, Meelan M.; Khorrami, Mehdi R.

    2006-01-01

    Previous studies have indicated that 2D, time accurate computations based on a pseudo-laminar zonal model of the slat cove region (within the framework of the Reynolds-Averaged Navier-Stokes equations) are inadequate for predicting the full unsteady dynamics of the slat cove flow field. Even though such computations could capture the large-scale, unsteady vorticity structures in the slat cove region without requiring any external forcing, the simulated vortices were excessively strong and the recirculation zone was unduly energetic in comparison with the PIV measurements for a generic high-lift configuration. To resolve this discrepancy and to help enable physics based predictions of slat aeroacoustics, the present paper is focused on 3D simulations of the slat cove flow over a computational domain of limited spanwise extent. Maintaining the pseudo-laminar approach, current results indicate that accounting for the three-dimensionality of flow fluctuations leads to considerable improvement in the accuracy of the unsteady, nearfield solution. Analysis of simulation data points to the likely significance of turbulent fluctuations near the reattachment region toward the generation of broadband slat noise. The computed acoustic characteristics (in terms of the frequency spectrum and spatial distribution) within short distances from the slat resemble the previously reported, subscale measurements of slat noise.

  19. Asymmetric effects at 3D Ising-like critical points

    NASA Astrophysics Data System (ADS)

    Tsypin, M.

    2003-05-01

    The Standard Model of electroweak interactions has a line of first order phase transition in the plane (higgs mass, temperature) that ends in a critical point belonging to the 3D Ising model universality class [K. Rummukainen et al, hep-lat/9805013. Similar critical points are found in finite-temperature QCD [M. Stephanov et al, hep-ph/9806219; F. Karsch et al, hep-lat/0107020. When these critical points are studied by Monte Carlo simulations on the lattice, one observes certain residual deviations from Z2 symmetry (which is exact for the Ising model). Here we study whether such deviations can be attributed to asymmetric corrections to scaling, which are relatively poorly studied. We compute the critical exponents in the local potential approximation (LPA), that is, in the framework of the Wegner-Houghton equation. We find that the exponent for the leading antisymmetric correction to scaling is approximately 1.691 in the LPA. This high value implies that such corrections cannot explain observed asymmetries.

  20. A fast technique applied to the analysis of Resistive Wall Modes with 3D conducting structures

    SciTech Connect

    Rubinacci, Guglielmo Liu, Yueqiang

    2009-03-20

    This paper illustrates the development of a 'fast' technique for the analysis of Resistive Wall Modes (RWMs) in fusion devices with three-dimensional conducting structures, by means of the recently developed CarMa code. Thanks to its peculiar features, the computational cost scales almost linearly with the number of discrete unknowns. Some large scale problems are solved in configurations of interest for the International Thermonuclear Experimental Reactor (ITER)

  1. Composite lithium metal anode by melt infusion of lithium into a 3D conducting scaffold with lithiophilic coating

    PubMed Central

    Liang, Zheng; Lin, Dingchang; Zhao, Jie; Lu, Zhenda; Liu, Yayuan; Liu, Chong; Lu, Yingying; Wang, Haotian; Yan, Kai; Tao, Xinyong; Cui, Yi

    2016-01-01

    Lithium metal-based battery is considered one of the best energy storage systems due to its high theoretical capacity and lowest anode potential of all. However, dendritic growth and virtually relative infinity volume change during long-term cycling often lead to severe safety hazards and catastrophic failure. Here, a stable lithium–scaffold composite electrode is developed by lithium melt infusion into a 3D porous carbon matrix with “lithiophilic” coating. Lithium is uniformly entrapped on the matrix surface and in the 3D structure. The resulting composite electrode possesses a high conductive surface area and excellent structural stability upon galvanostatic cycling. We showed stable cycling of this composite electrode with small Li plating/stripping overpotential (<90 mV) at a high current density of 3 mA/cm2 over 80 cycles. PMID:26929378

  2. Femtosecond pulsed light polarization induced effects in direct laser writing 3D nanolithography

    NASA Astrophysics Data System (ADS)

    Malinauskas, Mangirdas; RekštytÄ--, Sima; Jonavičius, Tomas; Gailevičius, Darius; Mizeikis, Vygantas; Gamaly, Eugene; Juodkazis, Saulius

    2016-03-01

    We demonstrate how the coupling between (i) polarization of the writing laser beam, (ii) tight focusing and (iii) heat conduction affects the size, shape and absorption in the laser-affected area and therefore the polymerization process. It is possible to control the sizes of 3D laser-produced structure at the scale of several nanometers. Specifically we were able to tune the aspect ratio of 3D suspended line up to 20% in hybrid SZ2080 resist. The focal spot of tightly focused linearly polarized beam has an elliptical form with the long axis in the field direction. It is shown here that this effect is enhanced by increase in the electronic heat conduction when polarization coincide with temperature gradient along with the absorption. Overlapping of three effects (i- iii) results in the difference of several tens of nanometers between two axes of the focal ellipse. Narrow line appears when polarization and scan direction coincide, while the wide line is produced when these directions are perpendicular to each other. The effect scales with the laser intensity giving a possibility to control the width of the structure on nanometer scale as demonstrated experimentally in this work. These effects are of general nature and can be observed in any laser-matter interaction experiments where plasma produced by using tight focusing of linear-polarized light.

  3. A Numerical Study on the Thermal Conductivity of 3D Woven C/C Composites at High Temperature

    NASA Astrophysics Data System (ADS)

    Shigang, Ai; Rujie, He; Yongmao, Pei

    2015-12-01

    Experimental data for Carbon/Carbon (C/C) constituent materials are combined with a three dimensional steady state heat transfer finite element analysis to demonstrate the average in-plane and out-of-plane thermal conductivities (TCs) of C/C composites. The finite element analysis is carried out at two distinct length scales: (a) a micro scale comparable with the diameter of carbon fibres and (b) a meso scale comparable with the carbon fibre yarns. Micro-scale model calculate the TCs at the fibre yarn scale in the three orthogonal directions ( x, y and z). The output results from the micro-scale model are then incorporated in the meso-scale model to obtain the global TCs of the 3D C/C composite. The simulation results are quite consistent with the theoretical and experimental counterparts reported in references. Based on the numerical approach, TCs of the 3D C/C composite are calculated from 300 to 2500 K. Particular attention is given in elucidating the variations of the TCs with temperature. The multi-scale models provide an efficient approach to predict the TCs of 3D textile materials, which is helpful for the thermodynamic property analysis and structure design of the C/C composites.

  4. 3-D parallel program for numerical calculation of gas dynamics problems with heat conductivity on distributed memory computational systems (CS)

    SciTech Connect

    Sofronov, I.D.; Voronin, B.L.; Butnev, O.I.

    1997-12-31

    The aim of the work performed is to develop a 3D parallel program for numerical calculation of gas dynamics problem with heat conductivity on distributed memory computational systems (CS), satisfying the condition of numerical result independence from the number of processors involved. Two basically different approaches to the structure of massive parallel computations have been developed. The first approach uses the 3D data matrix decomposition reconstructed at temporal cycle and is a development of parallelization algorithms for multiprocessor CS with shareable memory. The second approach is based on using a 3D data matrix decomposition not reconstructed during a temporal cycle. The program was developed on 8-processor CS MP-3 made in VNIIEF and was adapted to a massive parallel CS Meiko-2 in LLNL by joint efforts of VNIIEF and LLNL staffs. A large number of numerical experiments has been carried out with different number of processors up to 256 and the efficiency of parallelization has been evaluated in dependence on processor number and their parameters.

  5. Understanding the effects of dielectric medium, substrate, and depth on electric fields and SERS of quasi-3D plasmonic nanostructures.

    PubMed

    Xu, Jiajie; Kvasnička, Pavel; Idso, Matthew; Jordan, Roger W; Gong, Heng; Homola, Jiří; Yu, Qiuming

    2011-10-10

    The local electric field distribution and the effect of surface-enhanced Raman spectroscopy (SERS) were investigated on the quasi-3D (Q3D) plasmonic nanostructures formed by gold nanohole and nanodisc array layers physically separated by a dielectric medium. The local electric fields at the top gold nanoholes and bottom gold nanodiscs as a function of the dielectric medium, substrate, and depth of Q3D plasmonic nanostructures upon the irradiation of a 785 nm laser were calculated using the three-dimensional finite-difference time-domain (3D-FDTD) method. The intensity of the maximum local electric fields was shown to oscillate with the depth and the stronger local electric fields occurring at the top or bottom gold layer strongly depend on the dielectric medium, substrate, and depth of the nanostructure. This phenomenon was determined to be related to the Fabry-Pérot interference effect and the interaction of localized surface plasmons (LSPs). The enhancement factors (EFs) of SERS obtained from the 3D-FDTD simulations were compared to those calculated from the SERS experiments conducted on the Q3D plasmonic nanostructures fabricated on silicon and ITO coated glass substrates with different depths. The same trend was obtained from both methods. The capabilities of tuning not only the intensity but also the location of the maximum local electric fields by varying the depth, dielectric medium, and substrate make Q3D plasmonic nanostructures well suited for highly sensitive and reproducible SERS detection and analysis.

  6. Boosting Proton Conductivity in Highly Robust 3D Inorganic Cationic Extended Frameworks through Ion Exchange with Dihydrogen Phosphate Anions.

    PubMed

    Xiao, Chengliang; Wang, Yaxing; Chen, Lanhua; Yin, Xuemiao; Shu, Jie; Sheng, Daopeng; Chai, Zhifang; Albrecht-Schmitt, Thomas E; Wang, Shuao

    2015-12-01

    The limited long-term hydrolytic stability of rapidly emerging 3D-extended framework materials (MOFs, COFs, MOPs, etc.) is still one of major barriers for their practical applications as new solid-state electrolytes in fuel cells. To obtain hydrolytically stable materials, two H2 PO4 (-) -exchanged 3D inorganic cationic extended frameworks (CEFs) were successfully prepared by a facile anion-exchange method. Both anion-exchanged CEFs (YbO(OH)P and NDTBP) show significantly enhanced proton conductivity when compared with the original materials (YbO(OH)Cl and NDTB) with an increase of up to four orders-of-magnitude, reaching 2.36×10(-3) and 1.96×10(-2)  S cm(-1) at 98 % RH and 85 °C for YbO(OH)P and NDTBP, respectively. These values are comparable to the most efficient proton-conducting MOFs. In addition, these two anion-exchanged materials are stable in boiling water, which originates from the strong electrostatic interaction between the H2 PO4 (-) anion and the cationic host framework, showing a clear advance over all the acid-impregnated materials (H2 SO4 @MIL-101, H3 PO4 @MIL-101, and H3 PO4 @Tp-Azo) as practical solid-state fuel-cell electrolytes. This work offers a new general and efficient approach to functionalize 3D-extended frameworks through an anion-exchange process and achieves water-stability with ultra-high proton conductivity above 10(-2)  S cm(-1) .

  7. 3D imaging of soil apparent electrical conductivity from VERIS data using a 1D spatially constrained inversion algorithm

    NASA Astrophysics Data System (ADS)

    Jesús Moral García, Francisco; Rebollo Castillo, Francisco Javier; Monteiro Santos, Fernando

    2016-04-01

    Maps of apparent electrical conductivity of the soil are commonly used in precision agriculture to indirectly characterize some important properties like salinity, water, and clay content. Traditionally, these studies are made through an empirical relationship between apparent electrical conductivity and properties measured in soil samples collected at a few locations in the experimental area and at a few selected depths. Recently, some authors have used not the apparent conductivity values but the soil bulk conductivity (in 2D or 3D) calculated from measured apparent electrical conductivity through the application of an inversion method. All the published works used data collected with electromagnetic (EM) instruments. We present a new software to invert the apparent electrical conductivity data collected with VERIS 3100 and 3150 (or the more recent version with three pairs of electrodes) using the 1D spatially constrained inversion method (1D SCI). The software allows the calculation of the distribution of the bulk electrical conductivity in the survey area till a depth of 1 m. The algorithm is applied to experimental data and correlations with clay and water content have been established using soil samples collected at some boreholes. Keywords: Digital soil mapping; inversion modelling; VERIS; soil apparent electrical conductivity.

  8. Effectiveness of Collaborative Learning with 3D Virtual Worlds

    ERIC Educational Resources Information Center

    Cho, Young Hoan; Lim, Kenneth Y. T.

    2017-01-01

    Virtual worlds have affordances to enhance collaborative learning in authentic contexts. Despite the potential of collaborative learning with a virtual world, few studies investigated whether it is more effective in student achievements than teacher-directed instruction. This study investigated the effectiveness of collaborative problem solving…

  9. Shape-memory polymer nanocomposites with a 3D conductive network for bidirectional actuation and locomotion application.

    PubMed

    Peng, Qingyu; Wei, Hongqiu; Qin, Yuyang; Lin, Zaishan; Zhao, Xu; Xu, Fan; Leng, Jinsong; He, Xiaodong; Cao, Anyuan; Li, Yibin

    2016-10-27

    Electrical stimulation of shape-memory polymers (SMPs) has many advantages over thermal methods; creating an efficient conductive path through the bulk polymers is essential for developing high performance electroactive systems. Here, we show that a three-dimensional (3D) porous carbon nanotube sponge can serve as a built-in integral conductive network to provide internal, homogeneous, in situ Joule heating for shape-memory polymers, thus significantly improving the mechanical and thermal behavior of SMPs. As a result, the 3D nanocomposites show a fast response and produce large exerting forces (with a maximum flexural stress of 14.6 MPa) during shape recovery. We further studied the construction of a double-layer composite structure for bidirectional actuation, in which the shape change is dominated by the temperature-dependent exerting force from the top and bottom layer, alternately. An inchworm-type robot is demonstrated whose locomotion is realized by such bidirectional shape memory. Our large stroke shape-memory nanocomposites have promising applications in many areas including artificial muscles and bionic robots.

  10. Numerical simulation and inversion of MT fields in the 3D electric conductivity model of the Vesuvius volcano

    NASA Astrophysics Data System (ADS)

    Spichak, V. V.

    2011-01-01

    Possibilities for three-dimensional (3D) magnetotelluric (MT) sounding of local objects contained in the Earth's crust are estimated in a case study of the magma chamber of the Vesuvius volcano. Stochastic inversion of the model MT data by the Markov Chain Monte Carlo (MCMC) method has shown that the most efficient approach is not simultaneous but successive estimation of the geometry and the depth of the anomaly and the assessment of the conductivity distribution within the anomalous region. A zone of equivalence is revealed between the a priori estimate of the depth of the anomalous zone and the a posteriori distribution of electric conductivity within it. Based on the present estimation and previous results, an algorithm for determination of the parameters of local crustal anomaly is proposed.

  11. A Measure of the Effectiveness of Incorporating 3D Human Anatomy into an Online Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Hilbelink, Amy J.

    2009-01-01

    Results of a study designed to determine the effectiveness of implementing three-dimensional (3D) stereo images of a human skull in an undergraduate human anatomy online laboratory were gathered and analysed. Mental model theory and its applications to 3D relationships are discussed along with the research results. Quantitative results on 62 pairs…

  12. 3D polyaniline porous layer anchored pillared graphene sheets: enhanced interface joined with high conductivity for better charge storage applications.

    PubMed

    Sekar, Pandiaraj; Anothumakkool, Bihag; Kurungot, Sreekumar

    2015-04-15

    Here, we report synthesis of a 3-dimensional (3D) porous polyaniline (PANI) anchored on pillared graphene (G-PANI-PA) as an efficient charge storage material for supercapacitor applications. Benzoic acid (BA) anchored graphene, having spatially separated graphene layers (G-Bz-COOH), was used as a structure controlling support whereas 3D PANI growth has been achieved by a simple chemical oxidation of aniline in the presence of phytic acid (PA). The BA groups on G-Bz-COOH play a critical role in preventing the restacking of graphene to achieve a high surface area of 472 m(2)/g compared to reduced graphene oxide (RGO, 290 m(2)/g). The carboxylic acid (-COOH) group controls the rate of polymerization to achieve a compact polymer structure with micropores whereas the chelating nature of PA plays a crucial role to achieve the 3D growth pattern of PANI. This type of controlled interplay helps G-PANI-PA to achieve a high conductivity of 3.74 S/cm all the while maintaining a high surface area of 330 m(2)/g compared to PANI-PA (0.4 S/cm and 60 m(2)/g). G-PANI-PA thus conceives the characteristics required for facile charge mobility during fast charge-discharge cycles, which results in a high specific capacitance of 652 F/g for the composite. Owing to the high surface area along with high conductivity, G-PANI-PA displays a stable specific capacitance of 547 F/g even with a high mass loading of 3 mg/cm(2), an enhanced areal capacitance of 1.52 F/cm(2), and a volumetric capacitance of 122 F/cm(3). The reduced charge-transfer resistance (RCT) of 0.67 Ω displayed by G-PANI-PA compared to pure PANI (0.79 Ω) stands out as valid evidence of the improved charge mobility achieved by the system by growing the 3D PANI layer along the spatially separated layers of the graphene sheets. The low RCT helps the system to display capacitance retention as high as 65% even under a high current dragging condition of 10 A/g. High charge/discharge rates and good cycling stability are the other

  13. Genre Matters: A Comparative Study on the Entertainment Effects of 3D in Cinematic Contexts

    NASA Astrophysics Data System (ADS)

    Ji, Qihao; Lee, Young Sun

    2014-09-01

    Built upon prior comparative studies of 3D and 2D films, the current project investigates the effects of 2D and 3D on viewers' perception of enjoyment, narrative engagement, presence, involvement, and flow across three movie genres (Action/fantasy vs. Drama vs. Documentary). Through a 2 by 3 mixed factorial design, participants (n = 102) were separated into two viewing conditions (2D and 3D) and watched three 15-min film segments. Result suggested both visual production methods are equally efficient in terms of eliciting people's enjoyment, narrative engagement, involvement, flow and presence, no effects of visual production method was found. In addition, through examining the genre effects in both 3D and 2D conditions, we found that 3D works better for action movies than documentaries in terms of eliciting viewers' perception of enjoyment and presence, similarly, it improves views' narrative engagement for documentaries than dramas substantially. Implications and limitations are discussed in detail.

  14. Loading mode dependent effective properties of octet-truss lattice structures using 3D-printing

    NASA Astrophysics Data System (ADS)

    Challapalli, Adithya

    Cellular materials, often called lattice materials, are increasingly receiving attention for their ultralight structures with high specific strength, excellent impact absorption, acoustic insulation, heat dissipation media and compact heat exchangers. In alignment with emerging additive manufacturing (AM) technology, realization of the structural applications of the lattice materials appears to be becoming faster. Considering the direction dependent material properties of the products with AM, by directionally dependent printing resolution, effective moduli of lattice structures appear to be directionally dependent. In this paper, a constitutive model of a lattice structure, which is an octet-truss with a base material having an orthotropic material property considering AM is developed. In a case study, polyjet based 3D printing material having an orthotropic property with a 9% difference in the principal direction provides difference in the axial and shear moduli in the octet-truss by 2.3 and 4.6%. Experimental validation for the effective properties of a 3D printed octet-truss is done for uniaxial tension and compression test. The theoretical value based on the micro-buckling of truss member are used to estimate the failure strength. Modulus value appears a little overestimate compared with the experiment. Finite element (FE) simulations for uniaxial compression and tension of octettruss lattice materials are conducted. New effective properties for the octet-truss lattice structure are developed considering the observed behavior of the octet-truss structure under macroscopic compression and tension trough simulations.

  15. Hierarchical self-assembly of hexagonal single-crystal nanosheets into 3D layered superlattices with high conductivity

    NASA Astrophysics Data System (ADS)

    Tao, Yulun; Shen, Yuhua; Yang, Liangbao; Han, Bin; Huang, Fangzhi; Li, Shikuo; Chu, Zhuwang; Xie, Anjian

    2012-05-01

    While the number of man-made nano superstructures realized by self-assembly is growing in recent years, assemblies of conductive polymer nanocrystals, especially for superlattices, are still a significant challenge, not only because of the simplicity of the shape of the nanocrystal building blocks and their interactions, but also because of the poor control over these parameters in the fabrication of more elaborate nanocrystals. Here, we firstly report a facile and general route to a new generation of 3D layered superlattices of polyaniline doped with CSA (PANI-CSA) and show how PANI crystallize and self-assemble, in a suitable single solution environment. In cyclohexane, 1D amorphous nanofibers transformed to 1D nanorods as building blocks, and then to 2D single-crystal nanosheets with a hexagonal phase, and lastly to 3D ordered layered superlattices with the narrowest polydispersity value (Mw/Mn = 1.47). Remarkably, all the instructions for the hierarchical self-assembly are encoded in the layered shape in other non-polar solvents (hexane, octane) and their conductivity in the π-π stacking direction is improved to about 50 S cm-1, which is even higher than that of the highest previously reported value (16 S cm-1). The method used in this study is greatly expected to be readily scalable to produce superlattices of conductive polymers with high quality and low cost.While the number of man-made nano superstructures realized by self-assembly is growing in recent years, assemblies of conductive polymer nanocrystals, especially for superlattices, are still a significant challenge, not only because of the simplicity of the shape of the nanocrystal building blocks and their interactions, but also because of the poor control over these parameters in the fabrication of more elaborate nanocrystals. Here, we firstly report a facile and general route to a new generation of 3D layered superlattices of polyaniline doped with CSA (PANI-CSA) and show how PANI crystallize and

  16. A 3-D reconstruction solution to current density imaging based on acoustoelectric effect by deconvolution: a simulation study.

    PubMed

    Yang, Renhuan; Li, Xu; Song, Aiguo; He, Bin; Yan, Ruqiang

    2013-05-01

    Hybrid imaging modality combining ultrasound scanning and electrical current density imaging through the acoustoelectric (AE) effect may potentially provide solutions to imaging electrical activities and properties of biological tissues with high spatial resolution. In this study, a 3-D reconstruction solution to ultrasound current source density imaging (UCSDI) by means of Wiener deconvolution is proposed and evaluated through computer simulations. As compared to previous 2-D UCSDI problem, in a 3-D volume conductor with broadly distributed current density field, the AE signal becomes a 3-D convolution between the electric field and the acoustic field, and effective 3-D reconstruction algorithm has not been developed so far. In the proposed method, a 3-D ultrasound scanning is performed while the corresponding AE signals are collected from multiple electrode pairs attached on the surface of the imaging object. From the collected AE signals, the acoustic field and electric field were first decoupled by Wiener deconvolution. Then, the current density distribution was reconstructed by inverse projection. Our simulations using artificial current fields in homogeneous phantoms suggest that the proposed method is feasible and robust against noise. It is also shown that using the proposed method, it is feasible to reconstruct 3-D current density distribution in an inhomogeneous conductive medium.

  17. Critical factors affecting the 3D microstructural formation in hybrid conductive adhesive materials studied by X-ray nano-tomography

    NASA Astrophysics Data System (ADS)

    Chen-Wiegart, Yu-Chen Karen; Figueroa-Santos, Miriam Aileen; Petrash, Stanislas; Garcia-Miralles, Jose; Wang, Jun

    2014-12-01

    Conductive adhesives are found favorable in a wide range of applications including a lead-free solder in micro-chips, flexible and printable electronics and enhancing the performance of energy storage devices. Composite materials comprised of metallic fillers and a polymer matrix are of great interest to be implemented as hybrid conductive adhesives. Here we investigated a cost-effective conductive adhesive material consisting of silver-coated copper as micro-fillers using synchrotron-based three-dimensional (3D) X-ray nano-tomography. The key factors affecting the quality and performance of the material were quantitatively studied in 3D on the nanometer scale for the first time. A critical characteristic parameter, defined as a shape-factor, was determined to yield a high-quality silver coating, leading to satisfactory performance. A `stack-and-screen' mechanism was proposed to elaborate such a phenomenon. The findings and the technique developed in this work will facilitate the future advancement of conductive adhesives to have a great impact in micro-electronics and other applications.Conductive adhesives are found favorable in a wide range of applications including a lead-free solder in micro-chips, flexible and printable electronics and enhancing the performance of energy storage devices. Composite materials comprised of metallic fillers and a polymer matrix are of great interest to be implemented as hybrid conductive adhesives. Here we investigated a cost-effective conductive adhesive material consisting of silver-coated copper as micro-fillers using synchrotron-based three-dimensional (3D) X-ray nano-tomography. The key factors affecting the quality and performance of the material were quantitatively studied in 3D on the nanometer scale for the first time. A critical characteristic parameter, defined as a shape-factor, was determined to yield a high-quality silver coating, leading to satisfactory performance. A `stack-and-screen' mechanism was proposed to

  18. Effect of Illumination on Ocular Status Modifications Induced by Short-Term 3D TV Viewing

    PubMed Central

    Chen, Yuanyuan; Xu, Aiqin; Jiang, Jian

    2017-01-01

    Objectives. This study aimed to compare changes in ocular status after 3D TV viewing under three modes of illumination and thereby identify optimal illumination for 3D TV viewing. Methods. The following measures of ocular status were assessed: the accommodative response, accommodative microfluctuation, accommodative facility, relative accommodation, gradient accommodative convergence/accommodation (AC/A) ratio, phoria, and fusional vergence. The observers watched 3D television for 90 minutes through 3D shutter glasses under three illumination modes: A, complete darkness; B, back illumination (50 lx); and C, front illumination (130 lx). The ocular status of the observers was assessed both before and after the viewing. Results. After 3D TV viewing, the accommodative response and accommodative microfluctuation were significantly changed under illumination Modes A and B. The near positive fusional vergence decreased significantly after the 90-minute 3D viewing session under each illumination mode, and this effect was not significantly different among the three modes. Conclusions. Short-term 3D viewing modified the ocular status of adults. The least amount of such change occurred with front illumination, suggesting that this type of illumination is an appropriate mode for 3D shutter TV viewing. PMID:28348893

  19. Conductive polymer-mediated 2D and 3D arrays of Mn3O4 nanoblocks and mesoporous conductive polymers as their replicas.

    PubMed

    Nakagawa, Yoshitaka; Kageyama, Hiroyuki; Matsumoto, Riho; Oaki, Yuya; Imai, Hiroaki

    2015-11-28

    Orientation-controlled 2D and 3D microarrays of Mn3O4 nanocuboids that were mediated by a conductive polymer were fabricated by evaporation-induced self-assembly of the oxide nanoblocks and subsequent polymerization of pyrrole in the interparticle spaces. Free-standing mesoporous polypyrroles (PPy) having chain- and square-grid-like nanovoid arrays were obtained as replicas of the composite assemblies by dissolving the oxide nanoblocks. The PPy-mediated manganese oxide arrays exhibited stable electrochemical performance as an ultrathin anode of a lithium-ion secondary battery.

  20. Do Fractal Models of Clouds Produces the Right 3D Radiative Effects?

    NASA Technical Reports Server (NTRS)

    Varnai, Tamas; Marshak, Alexander; Einaudi, Franco (Technical Monitor)

    2001-01-01

    Stochastic fractal models of clouds are often used to study 3D radiative effects and their influence on the remote sensing of cloud properties. Since it is important that the cloud models produce a correct radiative response, some researchers require the model parameters to match observed cloud properties such as scale-independent optical thickness variability. Unfortunately, matching these properties does not necessarily imply that the cloud models will cause the right 3D radiative effects. First, the matched properties alone only influence the 3D effects but do not completely determine them. Second, in many cases the retrieved cloud properties have been already biased by 3D radiative effects, and so the models may not match the true real clouds. Finally, the matched cloud properties cannot be considered independent from the scales at which they have been retrieved. This paper proposes an approach that helps ensure that fractal cloud models are realistic and produce the right 3D effects. The technique compares the results of radiative transfer simulations for the model clouds to new direct observations of 3D radiative effects in satellite images.

  1. Three dimensional electrical conductivity model of the Northwestern US derived from 3-D inversion of USArray magnetotelluric data

    NASA Astrophysics Data System (ADS)

    Meqbel, N. M.; Egbert, G. D.; Kelbert, A.

    2011-12-01

    Long period (10-20,000 s) magnetotelluric (MT) data are being acquired in a series of temporary arrays deployed across the continental United States through the EMScope component of EarthScope. MT deployments in 2006-2011 have acquired data at 325 sites on an approximately regular grid, with the same nominal spacing as the USArray broadband seismic transportable array (~70 km). The MT sites span a rectangular area from NW Washington to NW Colorado. Here we present results of a 3-D inversion of the full data set. A number of conductive and resistive features appear consistently in the crust and upper mantle in essentially all of a large suite of 3-D inverse solutions. Extensive areas of high conductivity are found in the lower crust (up to a depth of ~ 40 km) beneath the Basin & Range in southeastern Oregon, as imaged by Patro and Egbert (2008). In our new model, this feature extends further to the south and to the east, where it merges with somewhat deeper (uppermost mantle) conductivities beneath the Yellowstone-Snake River Plain. This deeper feature, which extends from Yellowstone to the SW into northeastern Nevada, coincides with the track of the Yellowstone hotspot discussed e.g., in Smith et. al. (2008). The lower crust and the uppermost mantle in the northeastern part of the domain, covering the area from eastern Washington to Montana and continuing south to Wyoming, is generally resistive, with a few localized exceptions. This resistive zone coincides with high velocities discussed and interpreted, e.g., by Yang et. al. (2008) as thick, stable Proterozoic lithosphere. A number of large-scale anomalous features also appear consistently in the upper mantle, at depths of ~ 50 km to 300 km. Most striking is a zone of high resistivity on the western edge of the domain, beneath western Oregon, Washington and northern California in the area occupied by oceanic lithosphere of the Juan de Fuca Plate, which has subducted beneath the relatively more conductive

  2. Biotemplate synthesis of polyaniline@cellulose nanowhiskers/natural rubber nanocomposites with 3D hierarchical multiscale structure and improved electrical conductivity.

    PubMed

    Wu, Xiaodong; Lu, Canhui; Xu, Haoyu; Zhang, Xinxing; Zhou, Zehang

    2014-12-10

    Development of novel and versatile strategies to construct conductive polymer composites with low percolation thresholds and high mechanical properties is of great importance. In this work, we report a facile and effective strategy to prepare polyaniline@cellulose nanowhiskers (PANI@CNs)/natural rubber (NR) nanocomposites with 3D hierarchical multiscale structure. Specifically, PANI was synthesized in situ on the surface of CNs biotemplate to form PANI@CNs nanohybrids with high aspect ratio and good dispersity. Then NR latex was introduced into PANI@CNs nanohybrids suspension to enable the self-assembly of PANI@CNs nanohybrids onto NR latex microspheres. During cocoagulation process, PANI@CNs nanohybrids selectively located in the interstitial space between NR microspheres and organized into a 3D hierarchical multiscale conductive network structure in NR matrix. The combination of the biotemplate synthesis of PANI and latex cocoagulation method significantly enhanced the electrical conductivity and mechanical properties of the NR-based nanocomposites simultaneously. The electrical conductivity of PANI@CNs/NR nanocomposites containing 5 phr PANI showed 11 orders of magnitude higher than that of the PANI/NR composites at the same loading fraction,; meanwhile, the percolation threshold was drastically decreased from 8.0 to 3.6 vol %.

  3. A study on radiative transfer effects in 3-D cloudy atmosphere using satellite data

    NASA Astrophysics Data System (ADS)

    Okata, M.; Nakajima, T.; Suzuki, K.; Inoue, T.; Nakajima, T. Y.; Okamoto, H.

    2017-01-01

    This study evaluates 3-D cloud effects on the radiation budget with a combined use of active sensor cloud profiling radar/CloudSat and imager Moderate Resolution Imaging Spectroradiometer/Aqua data on the A-train. An algorithm is devised for constructing 3-D cloud fields based on satellite-observed cloud information. The 3-D cloud fields thus constructed are used to calculate the broadband solar and thermal radiative fluxes with a 3-D radiative transfer code developed by the authors. The aim of this study is to investigate the effects of cloud morphology on solar radiative transfer in cloudy atmosphere. For this purpose, 3-D cloud fields are constructed with the new satellite-based method, to which full 3D-RT (radiative transfer) simulations are applied. The simulated 3-D radiation fields are then used to examine and quantify errors of existing typical plane-parallel approximations, i.e., Plane-Parallel Approximation, Independent Pixel Approximation and Tilted Independent Pixel Approximation. Such 3D-RT simulations also serve to address another objective of this study, i.e., to devise an accurate approximation and to characterize the observed specific 3D-RT effects by the cloud morphology based on knowledge of idealized 3D-RT effects. We introduce a modified approach based on an optimum value of diffusivity factor to better approximate the radiative fluxes for arbitrary solar zenith angle determined from the results of 3-D radiative transfer simulations to redeem the overcorrections of these approximations for large solar zenith angles (SZAs). This new approach, called Slant path Independent Pixel Approximation, is found to be better than other approximations when SZA is large for some cloud cases. Based on the SZA dependence of the errors of these approximations relative to 3-D computations, satellite-observed real cloud cases are found to fall into either of three types of different morphologies, i.e., isolated cloud type, upper cloud-roughened type and lower

  4. Numerical investigation of 3D effects on a 2D-dominated shocked mixing layer

    NASA Astrophysics Data System (ADS)

    Reese, Daniel; Weber, Christopher

    2016-11-01

    A nominally two-dimensional interface, unstable to the Rayleigh-Taylor or Richtmyer-Meshkov instability, will become three-dimensional at high Reynolds numbers due to the growth of background noise and 3D effects like vortex stretching. This three-dimensionality changes macroscopic features, such as the perturbation growth rate and mixing, as it enhances turbulent dissipation. In this study, a 2D perturbation with small-scale, 3D fluctuations is modeled using the hydrodynamics code Miranda. A Mach 1.95 shockwave accelerates a helium-over-SF6 interface, similar to the experiments of Motl et al. ["Experimental validation of a Richtmyer-Meshkov scaling law over large density ratio and shock strength ranges," Phys. Fluids 21(12), 126102 (2009)], to explore the regime where a 2D dominated flow will experience 3D effects. We report on the structure, growth, and mixing of the post-shocked interface in 2D and 3D.

  5. Strategies for Effectively Visualizing a 3D Flow Using Volume Line Integral Convolution

    NASA Technical Reports Server (NTRS)

    Interrante, Victoria; Grosch, Chester

    1997-01-01

    This paper discusses strategies for effectively portraying 3D flow using volume line integral convolution. Issues include defining an appropriate input texture, clarifying the distinct identities and relative depths of the advected texture elements, and selectively highlighting regions of interest in both the input and output volumes. Apart from offering insights into the greater potential of 3D LIC as a method for effectively representing flow in a volume, a principal contribution of this work is the suggestion of a technique for generating and rendering 3D visibility-impeding 'halos' that can help to intuitively indicate the presence of depth discontinuities between contiguous elements in a projection and thereby clarify the 3D spatial organization of elements in the flow. The proposed techniques are applied to the visualization of a hot, supersonic, laminar jet exiting into a colder, subsonic coflow.

  6. Characteristics of visual fatigue under the effect of 3D animation.

    PubMed

    Chang, Yu-Shuo; Hsueh, Ya-Hsin; Tung, Kwong-Chung; Jhou, Fong-Yi; Lin, David Pei-Cheng

    2015-01-01

    Visual fatigue is commonly encountered in modern life. Clinical visual fatigue characteristics caused by 2-D and 3-D animations may be different, but have not been characterized in detail. This study tried to distinguish the differential effects on visual fatigue caused by 2-D and 3-D animations. A total of 23 volunteers were subjected to accommodation and vergence assessments, followed by a 40-min video game program designed to aggravate their asthenopic symptoms. The volunteers were then assessed for accommodation and vergence parameters again and directed to watch a 5-min 3-D video program, and then assessed again for the parameters. The results support that the 3-D animations caused similar characteristics in vision fatigue parameters in some specific aspects as compared to that caused by 2-D animations. Furthermore, 3-D animations may lead to more exhaustion in both ciliary and extra-ocular muscles, and such differential effects were more evident in the high demand of near vision work. The current results indicated that an arbitrary set of indexes may be promoted in the design of 3-D display or equipments.

  7. The effectiveness of 3-D marine systems as an exploration tool in the offshore Niger Delta

    SciTech Connect

    Idowu, A.O. )

    1993-09-01

    From inception in 1984, three-dimensional (3-D) marine surveys have been used widely for field development where commercial hydrocarbons were known to exist in Nigeria. The high-trace density and full 3-D migration provide a data set that allows detailed interpretation of complex geologic structures and, in many cases, provides good stratigraphic information as well. The result has been better placement of development wells, making field development more efficient and cost effective. Previous application of the 3-d method (i.e., reconaissance 3-D) as an exploration tool in 1987 has demonstrated its effectiveness for predrilling detailing of prospects in offshore Niger Delta in a situation where a large volume of seismic data were acquired at relatively reduced unit costs. The technique involves acquiring data along a line every 200 m spacing, while interpretation in 3-D data processing is applied for subsequent 3-D migration. Based on pattern recognition of events on the input traces, the links are established to allow traces to be formed between input locations by comparing several attributes of events on neighboring traces. A case history example from the offshore Niger delta shows that the collection costs for the reconnaissance 3-D method are comparable to two-dimensional detailing based on similar line kilometer and time duration for the survey. A trade-off between cost and technical specifications can be programmed by focusing on the geologic objective. The technique brings the advantage of 3-D methods, but not their costs, to the exploration phase of the search for petroleum, and it is highly recommended for exploration in frontier areas, particularly the deep offshore of the Niger Delta.

  8. Reproducibly creating hierarchical 3D carbon to study the effect of Si surface functionalization on the oxygen reduction reaction

    NASA Astrophysics Data System (ADS)

    Zeng, Yuze; Flores, Jose F.; Shao, Yu-Cheng; Guo, Jinghua; Chuang, Yi-De; Lu, Jennifer Q.

    2016-06-01

    We report a new method to reproducibly fabricate functional 3D carbon structures directly on a current collector, e.g. stainless steel. The 3D carbon platform is formed by direct growth of upright arrays of carbon nanofiber bundles on a roughened surface of stainless steel via the seed-assisted approach. Each bundle consists of about 30 individual carbon nanofibers with a diameter of 18 nm on average. We have found that this new platform offers adequate structural integrity. As a result, no reduction of the surface area during downstream chemical functionalization was observed. With a fixed and reproducible 3D structure, the effect of the chemistry of the grafted species on the oxygen reduction reaction has been systematically investigated. This investigation reveals for the first time that non-conductive Si with an appropriate electronic structure distorts the carbon electronic structure and consequently enhances ORR electrocatalysis. The strong interface provides excellent electron connectivity according to electrochemical analysis. This highly reproducible and stable 3D platform can serve as a stepping-stone for the investigation of the effect of carbon surface functionalization on electrochemical reactions in general.We report a new method to reproducibly fabricate functional 3D carbon structures directly on a current collector, e.g. stainless steel. The 3D carbon platform is formed by direct growth of upright arrays of carbon nanofiber bundles on a roughened surface of stainless steel via the seed-assisted approach. Each bundle consists of about 30 individual carbon nanofibers with a diameter of 18 nm on average. We have found that this new platform offers adequate structural integrity. As a result, no reduction of the surface area during downstream chemical functionalization was observed. With a fixed and reproducible 3D structure, the effect of the chemistry of the grafted species on the oxygen reduction reaction has been systematically investigated. This

  9. The effects of mycoplasma contamination upon the ability to form bioengineered 3D kidney cysts.

    PubMed

    DesRochers, Teresa M; Kuo, Ivana Y; Kimmerling, Erica P; Ehrlich, Barbara E; Kaplan, David L

    2015-01-01

    Mycoplasma contamination of cell cultures is a pervasive, often undiagnosed and ignored problem in many laboratories that can result in reduced cell proliferation and changes in gene expression. Unless contamination is specifically suspected, it is often undetected in two dimensional (2D) cultures and the resulting effects of mycoplasma contamination are rarely appreciated and can lead to incorrect conclusions. Three dimensional (3D) tissue cultures are increasingly utilized to explore tissue development and phenotype. However, 3D cultures are more complex than 2D cell cultures and require a more controlled cellular environment in order to generate structures necessary to mimic in vivo responses and are often maintained for longer time periods. Changes to the microenvironment are assumed to have a more extreme effect upon the success of 3D tissue cultures than 2D cell cultures, but the effects of mycoplasma have not been studied. To test this hypothesis, we grew 2D cell cultures and 3D tissues from pig kidney epithelial cells (LLC-PK1) that were contaminated with mycoplasma and the same stock of cells after mycoplasma removal. We did not observe an effect of mycoplasma contamination on proliferation in 2D monolayer cell culture. However, cyst formation in 3D tissues was altered, with effects upon the number, size and structure of cysts formed. These data serve to reinforce the necessity of testing cell stocks for mycoplasma contamination.

  10. Screening for Stromal and Matrix Effects in 3D Microenvironments of Breast Cancer Cells

    NASA Astrophysics Data System (ADS)

    Montanez-Sauri, Sara I.

    Breast cancer progression ensures through the acquisition of genetic mutations, the uncontrollable growth of cells, and their progression to invasion. Studies have shown that the surrounding three-dimensional (3D) microenvironment can also influence breast cancer cell progression by controlling the morphology, differentiation, proliferation, and migration of cells. However, most of the currently available in vitro screening platforms are based on the two-dimensional (2D) culture of cells, and do not provide cells with the complex 3D microenvironment that exists in vivo. Therefore, there is a need for more biologically relevant in vitro platforms to help decipher the complexity of the microenvironment and its influence in breast cancer. In this dissertation we present an automated microfluidic platform that allows to efficiently screen for the effect of multiple matrix and stromal microenvironment in 3D cultures of breast cancer cells. Several extracellular matrix (ECM) compositions and stromal cells are included in the 3D microenvironments to examine their influence on breast cancer cell behavior. The screening results suggest that collagen gels with fibronectin might be influencing paracrine signals between breast cancer cells and stromal cells. The ability of the platform to culture and treat cells in 3D microenvironments offers a powerful screening tool for the identification of compounds and interactions using more in vivo-like 3D microenvironments. The identification of these mechanisms will increase our current understanding of breast cancer, and will aid in the identification of potential therapeutics.

  11. Effects of point configuration on the accuracy in 3D reconstruction from biplane images

    SciTech Connect

    Dmochowski, Jacek; Hoffmann, Kenneth R.; Singh, Vikas; Xu Jinhui; Nazareth, Daryl P.

    2005-09-15

    Two or more angiograms are being used frequently in medical imaging to reconstruct locations in three-dimensional (3D) space, e.g., for reconstruction of 3D vascular trees, implanted electrodes, or patient positioning. A number of techniques have been proposed for this task. In this simulation study, we investigate the effect of the shape of the configuration of the points in 3D (the 'cloud' of points) on reconstruction errors for one of these techniques developed in our laboratory. Five types of configurations (a ball, an elongated ellipsoid (cigar), flattened ball (pancake), flattened cigar, and a flattened ball with a single distant point) are used in the evaluations. For each shape, 100 random configurations were generated, with point coordinates chosen from Gaussian distributions having a covariance matrix corresponding to the desired shape. The 3D data were projected into the image planes using a known imaging geometry. Gaussian distributed errors were introduced in the x and y coordinates of these projected points. Gaussian distributed errors were also introduced into the gantry information used to calculate the initial imaging geometry. The imaging geometries and 3D positions were iteratively refined using the enhanced-Metz-Fencil technique. The image data were also used to evaluate the feasible R-t solution volume. The 3D errors between the calculated and true positions were determined. The effects of the shape of the configuration, the number of points, the initial geometry error, and the input image error were evaluated. The results for the number of points, initial geometry error, and image error are in agreement with previously reported results, i.e., increasing the number of points and reducing initial geometry and/or image error, improves the accuracy of the reconstructed data. The shape of the 3D configuration of points also affects the error of reconstructed 3D configuration; specifically, errors decrease as the 'volume' of the 3D configuration

  12. Depth enhancement of S3D content and the psychological effects

    NASA Astrophysics Data System (ADS)

    Hirahara, Masahiro; Shiraishi, Saki; Kawai, Takashi

    2012-03-01

    Stereoscopic 3D (S3D) imaging technologies are widely used recently to create content for movies, TV programs, games, etc. Although S3D content differs from 2D content by the use of binocular parallax to induce depth sensation, the relationship between depth control and the user experience remains unclear. In this study, the user experience was subjectively and objectively evaluated in order to determine the effectiveness of depth control, such as an expansion or reduction or a forward or backward shift in the range of maximum parallactic angles in the cross and uncross directions (depth bracket). Four types of S3D content were used in the subjective and objective evaluations. The depth brackets of comparison stimuli were modified in order to enhance the depth sensation corresponding to the content. Interpretation Based Quality (IBQ) methodology was used for the subjective evaluation and the heart rate was measured to evaluate the physiological effect. The results of the evaluations suggest the following two points. (1) Expansion/reduction of the depth bracket affects preference and enhances positive emotions to the S3D content. (2) Expansion/reduction of the depth bracket produces above-mentioned effects more notable than shifting the cross/uncross directions.

  13. 2D fluid model analysis for the effect of 3D gas flow on a capacitively coupled plasma deposition reactor

    NASA Astrophysics Data System (ADS)

    Kim, Ho Jun; Lee, Hae June

    2016-06-01

    The wide applicability of capacitively coupled plasma (CCP) deposition has increased the interest in developing comprehensive numerical models, but CCP imposes a tremendous computational cost when conducting a transient analysis in a three-dimensional (3D) model which reflects the real geometry of reactors. In particular, the detailed flow features of reactive gases induced by 3D geometric effects need to be considered for the precise calculation of radical distribution of reactive species. Thus, an alternative inclusive method for the numerical simulation of CCP deposition is proposed to simulate a two-dimensional (2D) CCP model based on the 3D gas flow results by simulating flow, temperature, and species fields in a 3D space at first without calculating the plasma chemistry. A numerical study of a cylindrical showerhead-electrode CCP reactor was conducted for particular cases of SiH4/NH3/N2/He gas mixture to deposit a hydrogenated silicon nitride (SiN x H y ) film. The proposed methodology produces numerical results for a 300 mm wafer deposition reactor which agree very well with the deposition rate profile measured experimentally along the wafer radius.

  14. The effects of 3D asymmetries in ICF capsule implosions on the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Chittenden, Jeremy; Taylor, Shaun; Appelbe, Brian; Niasse, Nicholas

    2013-10-01

    We report on investigations into the effect of asymmetry on thermonuclear yield in ICF implosions on the NIF. 3D radiation hydrodynamics calculations of the entire capsule volume are presented which attempt to predict the structural form of the perturbations at the stagnation phase, based upon initial capsule defects, dust particles, radiation drive asymmetries, etc. Asymmetries arising at the interface between the hotspot and the cold dense fuel layer are further amplified by the Rayleigh-Taylor instability during the deceleration phase. Where multi-mode asymmetries interact in three dimensions, not all of kinetic energy is dissipated effectively. Low mode asymmetries which change the overall shape of the hotspot increase the surface area leading to increased thermal conduction. Higher mode asymmetries promote mixing of the cold fuel layer into the hotspot at stagnation. This essentially acts as an increased rate of ablation of the dense fuel at the hotspot surface, pulling material with low specific enthalpy into the hotpot, lowering the average hotspot temperature and quenching the burn. Signatures of the form of the perturbations are revealed in synthetic neutron spectra, X-ray images and radiography data.

  15. The effect of volumetric (3D) tactile symbols within inclusive tactile maps.

    PubMed

    Gual, Jaume; Puyuelo, Marina; Lloveras, Joaquim

    2015-05-01

    Point, linear and areal elements, which are two-dimensional and of a graphic nature, are the morphological elements employed when designing tactile maps and symbols for visually impaired users. However, beyond the two-dimensional domain, there is a fourth group of elements - volumetric elements - which mapmakers do not take sufficiently into account when it comes to designing tactile maps and symbols. This study analyses the effect of including volumetric, or 3D, symbols within a tactile map. In order to do so, the researchers compared two tactile maps. One of them uses only two-dimensional elements and is produced using thermoforming, one of the most popular systems in this field, while the other includes volumetric symbols, thus highlighting the possibilities opened up by 3D printing, a new area of production. The results of the study show that including 3D symbols improves the efficiency and autonomous use of these products.

  16. 3D calculation of Tucson-Melbourne 3NF effect in triton binding energy

    SciTech Connect

    Hadizadeh, M. R.; Tomio, L.; Bayegan, S.

    2010-08-04

    As an application of the new realistic three-dimensional (3D) formalism reported recently for three-nucleon (3N) bound states, an attempt is made to study the effect of three-nucleon forces (3NFs) in triton binding energy in a non partial wave (PW) approach. The spin-isospin dependent 3N Faddeev integral equations with the inclusion of 3NFs, which are formulated as function of vector Jacobi momenta, specifically the magnitudes of the momenta and the angle between them, are solved with Bonn-B and Tucson-Melbourne NN and 3N forces in operator forms which can be incorporated in our 3D formalism. The comparison with numerical results in both, novel 3D and standard PW schemes, shows that non PW calculations avoid the very involved angular momentum algebra occurring for the permutations and transformations and it is more efficient and less cumbersome for considering the 3NF.

  17. The effect of sound on visual fidelity perception in stereoscopic 3-D.

    PubMed

    Rojas, David; Kapralos, Bill; Hogue, Andrew; Collins, Karen; Nacke, Lennart; Cristancho, Sayra; Conati, Cristina; Dubrowski, Adam

    2013-12-01

    Visual and auditory cues are important facilitators of user engagement in virtual environments and video games. Prior research supports the notion that our perception of visual fidelity (quality) is influenced by auditory stimuli. Understanding exactly how our perception of visual fidelity changes in the presence of multimodal stimuli can potentially impact the design of virtual environments, thus creating more engaging virtual worlds and scenarios. Stereoscopic 3-D display technology provides the users with additional visual information (depth into and out of the screen plane). There have been relatively few studies that have investigated the impact that auditory stimuli have on our perception of visual fidelity in the presence of stereoscopic 3-D. Building on previous work, we examine the effect of auditory stimuli on our perception of visual fidelity within a stereoscopic 3-D environment.

  18. 3D near-to-surface conductivity reconstruction by inversion of VETEM data using the distorted Born iterative method

    USGS Publications Warehouse

    Wang, G.L.; Chew, W.C.; Cui, T.J.; Aydiner, A.A.; Wright, D.L.; Smith, D.V.

    2004-01-01

    Three-dimensional (3D) subsurface imaging by using inversion of data obtained from the very early time electromagnetic system (VETEM) was discussed. The study was carried out by using the distorted Born iterative method to match the internal nonlinear property of the 3D inversion problem. The forward solver was based on the total-current formulation bi-conjugate gradient-fast Fourier transform (BCCG-FFT). It was found that the selection of regularization parameter follow a heuristic rule as used in the Levenberg-Marquardt algorithm so that the iteration is stable.

  19. Effect of mental fatigue caused by mobile 3D viewing on selective attention: an ERP study.

    PubMed

    Mun, Sungchul; Kim, Eun-Soo; Park, Min-Chul

    2014-12-01

    This study investigated behavioral responses to and auditory event-related potential (ERP) correlates of mental fatigue caused by mobile three-dimensional (3D) viewing. Twenty-six participants (14 women) performed a selective attention task in which they were asked to respond to the sounds presented at the attended side while ignoring sounds at the ignored side before and after mobile 3D viewing. Considering different individual susceptibilities to 3D, participants' subjective fatigue data were used to categorize them into two groups: fatigued and unfatigued. The amplitudes of d-ERP components were defined as differences in amplitudes between time-locked brain oscillations of the attended and ignored sounds, and these values were used to calculate the degree to which spatial selective attention was impaired by 3D mental fatigue. The fatigued group showed significantly longer response times after mobile 3D viewing compared to before the viewing. However, response accuracy did not significantly change between the two conditions, implying that the participants used a behavioral strategy to cope with their performance accuracy decrement by increasing their response times. No significant differences were observed for the unfatigued group. Analysis of covariance revealed group differences with significant and trends toward significant decreases in the d-P200 and d-late positive potential (LPP) amplitudes at the occipital electrodes of the fatigued and unfatigued groups. Our findings indicate that mentally fatigued participants did not effectively block out distractors in their information processing mechanism, providing support for the hypothesis that 3D mental fatigue impairs spatial selective attention and is characterized by changes in d-P200 and d-LPP amplitudes.

  20. Model-based risk assessment for motion effects in 3D radiotherapy of lung tumors

    NASA Astrophysics Data System (ADS)

    Werner, René; Ehrhardt, Jan; Schmidt-Richberg, Alexander; Handels, Heinz

    2012-02-01

    Although 4D CT imaging becomes available in an increasing number of radiotherapy facilities, 3D imaging and planning is still standard in current clinical practice. In particular for lung tumors, respiratory motion is a known source of uncertainty and should be accounted for during radiotherapy planning - which is difficult by using only a 3D planning CT. In this contribution, we propose applying a statistical lung motion model to predict patients' motion patterns and to estimate dosimetric motion effects in lung tumor radiotherapy if only 3D images are available. Being generated based on 4D CT images of patients with unimpaired lung motion, the model tends to overestimate lung tumor motion. It therefore promises conservative risk assessment regarding tumor dose coverage. This is exemplarily evaluated using treatment plans of lung tumor patients with different tumor motion patterns and for two treatment modalities (conventional 3D conformal radiotherapy and step-&- shoot intensity modulated radiotherapy). For the test cases, 4D CT images are available. Thus, also a standard registration-based 4D dose calculation is performed, which serves as reference to judge plausibility of the modelbased 4D dose calculation. It will be shown that, if combined with an additional simple patient-specific breathing surrogate measurement (here: spirometry), the model-based dose calculation provides reasonable risk assessment of respiratory motion effects.

  1. The effect of motion on IMRT - looking at interplay with 3D measurements

    NASA Astrophysics Data System (ADS)

    Thomas, A.; Yan, H.; Oldham, M.; Juang, T.; Adamovics, J.; Yin, F. F.

    2013-06-01

    Clinical recommendations to address tumor motion management have been derived from studies dealing with simulations and 2D measurements. 3D measurements may provide more insight and possibly alter the current motion management guidelines. This study provides an initial look at true 3D measurements involving leaf motion deliveries by use of a motion phantom and the PRESAGE/DLOS dosimetry system. An IMRT and VMAT plan were delivered to the phantom and analyzed by means of DVHs to determine whether the expansion of treatment volumes based on known imaging motion adequately cover the target. DVHs confirmed that for these deliveries the expansion volumes were adequate to treat the intended target although further studies should be conducted to allow for differences in parameters that could alter the results, such as delivery dose and breathe rate.

  2. Effect of Ductile Agents on the Dynamic Behavior of SiC3D Network Composites

    NASA Astrophysics Data System (ADS)

    Zhu, Jingbo; Wang, Yangwei; Wang, Fuchi; Fan, Qunbo

    2016-10-01

    Co-continuous SiC ceramic composites using pure aluminum, epoxy, and polyurethane (PU) as ductile agents were developed. The dynamic mechanical behavior and failure mechanisms were investigated experimentally using the split Hopkinson pressure bar (SHPB) method and computationally by finite element (FE) simulations. The results show that the SiC3D/Al composite has the best overall performance in comparison with SiC3D/epoxy and SiC3D/PU composites. FE simulations are generally consistent with experimental data. These simulations provide valuable help in predicting mechanical strength and in interpreting the experimental results and failure mechanisms. They may be combined with micrographs for fracture characterizations of the composites. We found that interactions between the SiC phase and ductile agents under dynamic compression in the SHPB method are complex, and that interfacial condition is an important parameter that determines the mechanical response of SiC3D composites with a characteristic interlocking structure during dynamic compression. However, the effect of the mechanical properties of ductile agents on dynamic behavior of the composites is a second consideration in the production of the composites.

  3. Mechanical properties and shape memory effect of 3D-printed PLA-based porous scaffolds.

    PubMed

    Senatov, F S; Niaza, K V; Zadorozhnyy, M Yu; Maksimkin, A V; Kaloshkin, S D; Estrin, Y Z

    2016-04-01

    In the present work polylactide (PLA)/15wt% hydroxyapatite (HA) porous scaffolds with pre-modeled structure were obtained by 3D-printing by fused filament fabrication. Composite filament was obtained by extrusion. Mechanical properties, structural characteristics and shape memory effect (SME) were studied. Direct heating was used for activation of SME. The average pore size and porosity of the scaffolds were 700μm and 30vol%, respectively. Dispersed particles of HA acted as nucleation centers during the ordering of PLA molecular chains and formed an additional rigid fixed phase that reduced molecular mobility, which led to a shift of the onset of recovery stress growth from 53 to 57°C. A more rapid development of stresses was observed for PLA/HA composites with the maximum recovery stress of 3.0MPa at 70°C. Ceramic particles inhibited the growth of cracks during compression-heating-compression cycles when porous PLA/HA 3D-scaffolds recovered their initial shape. Shape recovery at the last cycle was about 96%. SME during heating may have resulted in "self-healing" of scaffold by narrowing the cracks. PLA/HA 3D-scaffolds were found to withstand up to three compression-heating-compression cycles without delamination. It was shown that PLA/15%HA porous scaffolds obtained by 3D-printing with shape recovery of 98% may be used as self-fitting implant for small bone defect replacement owing to SME.

  4. 3D-printing and the effect on medical costs: a new era?

    PubMed

    Choonara, Yahya E; du Toit, Lisa C; Kumar, Pradeep; Kondiah, Pierre P D; Pillay, Viness

    2016-01-01

    3D-printing (3DP) is the art and science of printing in a new dimension using 3D printers to transform 3D computer aided designs (CAD) into life-changing products. This includes the design of more effective and patient-friendly pharmaceutical products as well as bio-inspired medical devices. It is poised as the next technology revolution for the pharmaceutical and medical-device industries. After decorous implementation scientists in collaboration with CAD designers have produced innovative medical devices ranging from pharmaceutical tablets to surgical transplants of the human face and skull, spinal implants, prosthetics, human organs and other biomaterials. While 3DP may be cost-efficient, a limitation exists in the availability of 3D printable biomaterials for most applications. In addition, the loss of skilled labor in producing medical devices such as prosthetics and other devices may affect developing economies. This review objectively explores the potential growth and impact of 3DP costs in the medical industry.

  5. Effects of camera location on the reconstruction of 3D flare trajectory with two cameras

    NASA Astrophysics Data System (ADS)

    Özsaraç, Seçkin; Yeşilkaya, Muhammed

    2015-05-01

    Flares are used as valuable electronic warfare assets for the battle against infrared guided missiles. The trajectory of the flare is one of the most important factors that determine the effectiveness of the counter measure. Reconstruction of the three dimensional (3D) position of a point, which is seen by multiple cameras, is a common problem. Camera placement, camera calibration, corresponding pixel determination in between the images of different cameras and also the triangulation algorithm affect the performance of 3D position estimation. In this paper, we specifically investigate the effects of camera placement on the flare trajectory estimation performance by simulations. Firstly, 3D trajectory of a flare and also the aircraft, which dispenses the flare, are generated with simple motion models. Then, we place two virtual ideal pinhole camera models on different locations. Assuming the cameras are tracking the aircraft perfectly, the view vectors of the cameras are computed. Afterwards, using the view vector of each camera and also the 3D position of the flare, image plane coordinates of the flare on both cameras are computed using the field of view (FOV) values. To increase the fidelity of the simulation, we have used two sources of error. One is used to model the uncertainties in the determination of the camera view vectors, i.e. the orientations of the cameras are measured noisy. Second noise source is used to model the imperfections of the corresponding pixel determination of the flare in between the two cameras. Finally, 3D position of the flare is estimated using the corresponding pixel indices, view vector and also the FOV of the cameras by triangulation. All the processes mentioned so far are repeated for different relative camera placements so that the optimum estimation error performance is found for the given aircraft and are trajectories.

  6. Fitting-determined formulation of effective medium approximation for 3D trench structures in model-based infrared reflectrometry.

    PubMed

    Zhang, Chuanwei; Liu, Shiyuan; Shi, Tielin; Tang, Zirong

    2011-02-01

    The success of the model-based infrared reflectrometry (MBIR) technique relies heavily on accurate modeling and fast calculation of the infrared metrology process, which continues to be a challenge, especially for three-dimensional (3D) trench structures. In this paper, we present a simplified formulation for effective medium approximation (EMA), determined by a fitting-based method for the modeling of 3D trench structures. Intensive investigations have been performed with an emphasis on the generality of the fitting-determined (FD)-EMA formulation in terms of trench depth, trench pitch, and incidence angle so that its application is not limited to a particular configuration. Simulations conducted on a taper trench structure have further verified the proposed FD-EMA and demonstrated that the MBIR metrology with the FD-EMA-based model achieves an accuracy one order higher than that of the conventional zeroth-order EMA-based model.

  7. An investigation of unsteady 3D effects on trailing edge flaps

    NASA Astrophysics Data System (ADS)

    Jost, E.; Fischer, A.; Lutz, T.; Krämer, E.

    2016-09-01

    The present study investigates the impact of unsteady and viscous three-dimensional aerodynamic effects on a wind turbine blade with trailing edge flap by means of CFD. Harmonic oscillations are simulated on the DTU 10 MW rotor with a flap of 10% chord extent ranging from 70% to 80% blade radius. The deflection frequency is varied in the range between 1p and 6p. To quantify 3D effects, rotor simulations are compared to 2D airfoil computations. A significant influence of trailing and shed vortex structures has been found which leads to a reduction of the lift amplitude and hysteresis effects in the lift response with regard to the flap deflection. In the 3D rotor results greater amplitude reductions and less hystereses have been found compared to the 2D airfoil simulations.

  8. Effect of Resonant Magnetic Perturbations on 3D equilibria in the MST RFP

    NASA Astrophysics Data System (ADS)

    Munaretto, Stefano

    2015-11-01

    The orientation of 3D, stellarator-like equilibria in the MST RFP can now be controlled with application of an m = 1 RMP. This has led to greatly improved diagnosis, revealing enhancements in both the central electron temperature and density. Coupled to a recent advance in the V3FIT code, reconstructions of the 3D equilibria have also been dramatically improved. The RMP also inhibits the generation of high-energy >20 keV electrons that is otherwise common with the 3D state. This state occurs when the normally broad spectrum of core-resonant m = 1 tearing modes condenses, with the innermost resonant mode growing to large amplitude, reaching ~ 8% of the axisymmetric field strength. This occurs in plasmas of sufficiently large Lundquist number ~ IpTe3/2, and the duration of the state is maximized with zero applied Bt (infinite toroidal beta). As the dominant mode grows, eddy current in MST's conducting shell slows the mode's rotation. This leads to locking of the 3D structure, but with an orientation that varies randomly shot to shot, making diagnosis difficult. An m = 1 RMP can now be applied with an array of saddle coils at the vertical insulated cut in the shell. With an amplitude br/B ~ 10% and a tailored temporal waveform, the RMP can force the 3D structure into any desired orientation relative to MST's diagnostics. A recent advance in V3FIT allows calculation of the substantial helical image current flowing in MST's shell, which has in turn allowed self-consistent utilization of both external and internal (Faraday rotation) measurements of the magnetic field. The ORBIT code predicts reduced stochasticity and improved confinement of high-energy electrons within the 3D structure. The suppression of these electrons by the m = 1 RMP may reflect a change to the central magnetic topology. The generation of these electrons is unaffected by non-resonant perturbations, such as m = 3. Supported by the US DOE.

  9. Stress-induced Effects Caused by 3D IC TSV Packaging in Advanced Semiconductor Device Performance

    NASA Astrophysics Data System (ADS)

    Sukharev, V.; Kteyan, A.; Choy, J.-H.; Hovsepyan, H.; Markosian, A.; Zschech, E.; Huebner, R.

    2011-11-01

    Potential challenges with managing mechanical stress and the consequent effects on device performance for advanced 3D through-silicon-via (TSV) based technologies are outlined. The paper addresses the growing need in a simulation-based design verification flow capable to analyze a design of 3D IC stacks and to determine across-die out-of-spec variations in device electrical characteristics caused by the layout and through-silicon-via (TSV)/package-induced mechanical stress. The limited characterization/measurement capabilities for 3D IC stacks and a strict "good die" requirement make this type of analysis critical for the achievement of an acceptable level of functional and parametric yield and reliability. The paper focuses on the development of a design-for-manufacturability (DFM) type of methodology for managing mechanical stresses during a sequence of designs of 3D TSV-based dies, stacks and packages. A set of physics-based compact models for a multi-scale simulation to assess the mechanical stress across the device layers in silicon chips stacked and packaged with the 3D TSV technology is proposed. A calibration technique based on fitting to measured stress components and electrical characteristics of the test-chip devices is presented. A strategy for generation of a simulation feeding data and respective materials characterization approach are proposed, with the goal to generate a database for multi-scale material parameters of wafer-level and package-level structures. For model validation, high-resolution strain measurements in Si channels of the test-chip devices are needed. At the nanoscale, the transmission electron microscopy (TEM) is the only technique available for sub-10 nm strain measurements so far.

  10. An orientation measurement method based on Hall-effect sensors for permanent magnet spherical actuators with 3D magnet array.

    PubMed

    Yan, Liang; Zhu, Bo; Jiao, Zongxia; Chen, Chin-Yin; Chen, I-Ming

    2014-10-24

    An orientation measurement method based on Hall-effect sensors is proposed for permanent magnet (PM) spherical actuators with three-dimensional (3D) magnet array. As there is no contact between the measurement system and the rotor, this method could effectively avoid friction torque and additional inertial moment existing in conventional approaches. Curved surface fitting method based on exponential approximation is proposed to formulate the magnetic field distribution in 3D space. The comparison with conventional modeling method shows that it helps to improve the model accuracy. The Hall-effect sensors are distributed around the rotor with PM poles to detect the flux density at different points, and thus the rotor orientation can be computed from the measured results and analytical models. Experiments have been conducted on the developed research prototype of the spherical actuator to validate the accuracy of the analytical equations relating the rotor orientation and the value of magnetic flux density. The experimental results show that the proposed method can measure the rotor orientation precisely, and the measurement accuracy could be improved by the novel 3D magnet array. The study result could be used for real-time motion control of PM spherical actuators.

  11. Modeling the Impact of Drizzle and 3D Cloud Structure on Remote Sensing of Effective Radius

    NASA Technical Reports Server (NTRS)

    Platnick, Steven; Zinner, Tobias; Ackerman, S.

    2008-01-01

    Remote sensing of cloud particle size with passive sensors like MODIS is an important tool for cloud microphysical studies. As a measure of the radiatively relevant droplet size, effective radius can be retrieved with different combinations of visible through shortwave infrared channels. MODIS observations sometimes show significantly larger effective radii in marine boundary layer cloud fields derived from the 1.6 and 2.1 pm channel observations than for 3.7 pm retrievals. Possible explanations range from 3D radiative transport effects and sub-pixel cloud inhomogeneity to the impact of drizzle formation on the droplet distribution. To investigate the potential influence of these factors, we use LES boundary layer cloud simulations in combination with 3D Monte Carlo simulations of MODIS observations. LES simulations of warm cloud spectral microphysics for cases of marine stratus and broken stratocumulus, each for two different values of cloud condensation nuclei density, produce cloud structures comprising droplet size distributions with and without drizzle size drops. In this study, synthetic MODIS observations generated from 3D radiative transport simulations that consider the full droplet size distribution will be generated for each scene. The operational MODIS effective radius retrievals will then be applied to the simulated reflectances and the results compared with the LES microphysics.

  12. Simulation of sub-wavelength 3D photomask induced polarization effect by RCWA

    NASA Astrophysics Data System (ADS)

    Yang, Liang; Li, Yanqiu; Liu, Lihui; Wang, Jianfeng

    2012-10-01

    In 45nm technology node and beyond with hyper NA and Off-axis Illumination (OAI) lithography, mask induced polarization effect is remarkable. At this scale, traditional Kirchhoff approximation, in which the masks are considered to be infinitely thin objects, is no longer valid. Rigorous three-dimensional (3D) mask model is required for precise evaluation of mask diffraction. In this paper, a general 3D mask model based on the rigorous coupled-wave analysis (RCWA) is presented, and the change of polarization state as a function of mask and incident light properties is evaluated. The masks considered are the binary chrome mask and 10% Si-Si3N4 attenuated phase shifting mask. The results show that the mask induced polarization effects depend on the mask and incident light properties, such as mask material, absorber thickness, mask pitch, feature size, the polarization and incident angle of the light.

  13. Effect of Random Geometric Uncertainty on the Computational Design of a 3-D Flexible Wing

    NASA Technical Reports Server (NTRS)

    Gumbert, C. R.; Newman, P. A.; Hou, G. J.-W.

    2002-01-01

    The effect of geometric uncertainty due to statistically independent, random, normally distributed shape parameters is demonstrated in the computational design of a 3-D flexible wing. A first-order second-moment statistical approximation method is used to propagate the assumed input uncertainty through coupled Euler CFD aerodynamic / finite element structural codes for both analysis and sensitivity analysis. First-order sensitivity derivatives obtained by automatic differentiation are used in the input uncertainty propagation. These propagated uncertainties are then used to perform a robust design of a simple 3-D flexible wing at supercritical flow conditions. The effect of the random input uncertainties is shown by comparison with conventional deterministic design results. Sample results are shown for wing planform, airfoil section, and structural sizing variables.

  14. 3D Cloud Effects in OCO-2 Observations - Evidence and Mitigation

    NASA Astrophysics Data System (ADS)

    Schmidt, Sebastian; Massie, Steven; Iwabuchi, Hironobu; Okamura, Rintaro; Crisp, David

    2016-04-01

    In July 2014, the NASA Orbiting Carbon Observatory (OCO-2) satellite was inserted into the 705-km Afternoon Constellation (A-Train). OCO-2 provides estimates of column-averaged CO2 dry air mixing ratios (XCO2), based on high spectral resolution radiance observations of reflected sunlight in the O2 A-band and in the weak and strong absorption CO2 bands at 1.6 and 2.1 μm. The accuracy requirement for OCO-2 XCO2 retrievals is 1 ppmv on regional scales (> 1000 km). At the single sounding level, inhomogeneous clouds, surface albedo, and aerosols introduce wavelength-dependent perturbations into the sensed radiance fields, affecting the retrieval products. Scattering and shadowing by clouds outside of the field of view (FOV) may be a leading source of error for clear-sky XCO2 retrievals in partially cloudy regions. To understand these effects, we developed a 3D OCO-2 simulator, which uses observations by MODIS (also in the A-Train) and other scene information as input to simulate OCO-2 radiance spectra at the full wavelength resolution of the three bands. It is based on MCARaTS (Monte Carlo Atmospheric Radiative Transfer Simulator) as the 3D radiative transfer solver. The OCO-2 3D simulator was applied to an observed scene near a Total Carbon Column Observing Network (TCCON) station. The 3D calculations reproduced the OCO-2 radiances, including the perturbations due to clouds, at the single sounding level. The analysis further suggests that clouds near an OCO-2 footprint leave systematic spectral imprints on the radiances, which could be parameterized to be included in the retrieval state vector. If successful, this new state vector element could account for 3D effects without the need for operational 3D radiative transfer calculations. This may be the starting point not only for the improved screening of low-level broken boundary layer clouds, but also for mitigating the effects of nearby clouds at the radiance level, thus improving the accuracy of retrievals in

  15. The Effect of 3D-Modeling Training on Students' Spatial Reasoning Relative to Gender and Grade

    ERIC Educational Resources Information Center

    Šafhalter, Andrej; Vukman, Karin Bakracevic; Glodež, Srecko

    2016-01-01

    The aim of this research was to establish whether gender and age have an impact on spatial reasoning and its development through the use of 3D modeling. The study was conducted on a sample of 196 children from sixth to ninth grade, of whom 95 represented the experimental group and 101 the control group. The experimental group received 3D modeling…

  16. Effectiveness Evaluation of Force Protection Training Using Computer-Based Instruction and X3d Simulation

    DTIC Science & Technology

    2007-09-01

    to growing operational constraints accelerated by the Global War on Terror, the United States Navy is looking for alternative methods of training to...accomplished efficiently and effectively, saving the U.S. Navy time and resources while maintaining a high state of readiness. The goal of this thesis is...COMPUTER-BASED INSTRUCTION AND X3D SIMULATION Wilfredo Cruzbaez Lieutenant, United States Navy B.A., Norfolk State University, 2001 Submitted in

  17. Quantifying the Effect of 3D Spatial Resolution on the Accuracy of Microstructural Distributions (PREPRINT)

    DTIC Science & Technology

    2012-08-01

    Michael D. Uchic and Michael Groeber Metals Branch Structural Materials Division Megna Shah UES, Inc. Gregory Loughnane, Raghavan Srinivasan...AUTHOR(S) Michael D. Uchic and Michael Groeber (AFRL/RXCM) Megna Shah (UES, Inc.) Gregory Loughnane, Raghavan Srinivasan, and Ramana Grandhi (Wright...effect of 3D spatial resolution on the accuracy of microstructural distributions Gregory Loughnane 1 , Michael Groeber 2 , Michael Uchic 2 , Matthew

  18. A Radiative Transfer Case Study for 3-d cloud effects in the UV

    NASA Astrophysics Data System (ADS)

    Meerkötter, Ralf; Degünther, Markus

    Satellite UV mapping is usually based on the independent pixel approximation (IPA) which neglects horizontal photon transport between adjacent columns. Horizontal inhomogeneity of cloud fields therefore causes uncertainties in the derived UV radiation fields. While these effects are small for large pixel satellites, the broken-cloud errors increase as the pixel size decreases. By comparing results of 1-d and 3-d UV radiative transfer calculations for three selected cloud scenes that cover a rather broad range of cloud inhomogeneity the main 3-d cloud effects on the atmospheric UV transmission are identified and quantified in their order of magnitude. With respect to the different spatial resolutions of satellite instruments it is further shown how 3-d cloud effects average out with increasing spatial scale. It turns out that locally the IPA cause maximum uncertainties up to ±100% for a spatial resolution of about 1 × 1 km² (e.g., AVHRR), they are reduced to ±10% for a resolution of about 15 × 15 km² and below 5% for a resolution greater than 30 km (e.g., TOMS).

  19. Effect of postural changes on 3D joint angular velocity during starting block phase.

    PubMed

    Slawinski, Jean; Dumas, Raphaël; Cheze, Laurence; Ontanon, Guy; Miller, Christian; Mazure-Bonnefoy, Alice

    2013-01-01

    Few studies have focused on the effect of posture during sprint start. The aim of this study was to measure the effect of the modification of horizontal distance between the blocks during sprint start on three dimensional (3D) joint angular velocity. Nine trained sprinters started using three different starting positions (bunched, medium and elongated). They were equipped with 63 passive reflective markers, and an opto-electronic Motion Analysis system was used to collect the 3D marker trajectories. During the pushing phase on the blocks, norm of the joint angular velocity (NJAV), 3D Euler angular velocity (EAV) and pushing time on the blocks were calculated. The results demonstrated that the decrease of the block spacing induces an opposite effect on the angular velocity of joints of the lower and the upper limbs. The NJAV of the upper limbs is greater in the bunched start, whereas the NJAV of the lower limbs is smaller. The modifications of NJAV were due to a combination of the movement of the joints in the different degrees of freedom. The medium start seems to be the best compromise because it leads, in a short pushing time, to a combination of optimal joint velocities for upper and lower segments.

  20. Effect of tow alignment on the mechanical performance of 3D woven textile composites

    NASA Technical Reports Server (NTRS)

    Norman, Timothy L.; Allison, Patti; Baldwin, Jack W.; Gracias, Brian K.; Seesdorf, Dave

    1993-01-01

    Three-dimensional (3D) woven preforms are currently being considered for use as primary structural components. Lack of technology to properly manufacture, characterize and predict mechanical properties, and predict damage mechanisms leading to failure are problems facing designers of textile composite materials. Two material systems with identical specifications but different manufacturing approaches are investigated. One manufacturing approach resulted in an irregular (nonuniform) preform geometry. The other approach yielded the expected preform geometry (uniform). The objectives are to compare the mechanical properties of the uniform and nonuniform angle interlock 3D weave constructions. The effect of adding layers of laminated tape to the outer surfaces of the textile preform is also examined. Damage mechanisms are investigated and test methods are evaluated.

  1. Effects of 3D random correlated velocity perturbations on predicted ground motions

    USGS Publications Warehouse

    Hartzell, S.; Harmsen, S.; Frankel, A.

    2010-01-01

    Three-dimensional, finite-difference simulations of a realistic finite-fault rupture on the southern Hayward fault are used to evaluate the effects of random, correlated velocity perturbations on predicted ground motions. Velocity perturbations are added to a three-dimensional (3D) regional seismic velocity model of the San Francisco Bay Area using a 3D von Karman random medium. Velocity correlation lengths of 5 and 10 km and standard deviations in the velocity of 5% and 10% are considered. The results show that significant deviations in predicted ground velocities are seen in the calculated frequency range (≤1 Hz) for standard deviations in velocity of 5% to 10%. These results have implications for the practical limits on the accuracy of scenario ground-motion calculations and on retrieval of source parameters using higher-frequency, strong-motion data.

  2. 3D scaffold with effective multidrug sequential release against bacteria biofilm.

    PubMed

    García-Alvarez, Rafaela; Izquierdo-Barba, Isabel; Vallet-Regí, María

    2017-02-01

    Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved with the design of 3D implants, which combine the merits of osseous regeneration and local multidrug therapy so as to avoid bacterial growth, drug resistance and the feared side effects. Herein, hierarchical 3D multidrug scaffolds based on nanocomposite bioceramic and polyvinyl alcohol (PVA) prepared by rapid prototyping with an external coating of gelatin-glutaraldehyde (Gel-Glu) have been fabricated. These 3D scaffolds contain three antimicrobial agents (rifampin, levofloxacin and vancomycin), which have been localized in different compartments of the scaffold to obtain different release kinetics and more effective combined therapy. Levofloxacin was loaded into the mesopores of nanocomposite bioceramic part, vancomycin was localized into PVA biopolymer part and rifampin was loaded in the external coating of Gel-Glu. The obtained results show an early and fast release of rifampin followed by sustained and prolonged release of vancomycin and levofloxacin, respectively, which are mainly governed by the progressive in vitro degradability rate of these scaffolds. This combined therapy is able to destroy Gram-positive and Gram-negative bacteria biofilms as well as inhibit the bacteria growth. In addition, these multifunctional scaffolds exhibit excellent bioactivity as well as good biocompatibility with complete cell colonization of preosteoblast in the entire surface, ensuring good bone regeneration. These findings suggest that these hierarchical 3D multidrug scaffolds are promising candidates as platforms for local bone infection therapy.

  3. A Cost-Effective Method to Assemble Biomimetic 3D Cell Culture Platforms

    PubMed Central

    Khalil, Sabreen; El-Badri, Nagwa; El-Mokhtaar, Mohamed; Al-Mofty, Saif; Farghaly, Mohamed; Ayman, Radwa; Habib, Dina; Mousa, Noha

    2016-01-01

    Developing effective stem cell based therapies requires the design of complex in vitro culture systems for more accurate representation of the stem cell niche. Attempts to improve conventional cell culture platforms include the use of biomaterial coated culture plates, sphere culture, microfluidic systems and bioreactors. Most of these platforms are not cost-effective, require industrial technical expertise to fabricate, and remain too simplistic compared to the physiological cell niche. The human amniotic membrane (hAM) has been used successfully in clinical grafting applications due to its unique biological composition and regenerative properties. In this study, we present a combinatorial platform that integrates the hAM with biomolecular, topographic and mechanical cues in one versatile model. Methods We utilized the hAM to provide the biological and the three dimensional (3D) topographic components of the prototype. The 3D nano-roughness of the hAM was characterized using surface electron microscopy and surface image analysis (ImageJ and SurfaceJ). We developed additional macro-scale and micro-scale versions of the platform which provided additional shear stress factors to simulate the fluid dynamics of the in vivo extracellular fluids. Results Three models of varying complexities of the prototype were assembled. A well-defined 3D surface modulation of the hAM in comparable to commercial 3D biomaterial culture substrates was achieved without complex fabrication and with significantly lower cost. Performance of the prototype was demonstrated through culture of primary human umbilical cord mononuclear blood cells (MNCs), human bone marrow mesenchymal stem cell line (hBMSC), and human breast cancer tissue. Conclusion This study presents methods of assembling an integrated, flexible and low cost biomimetic cell culture platform for diverse cell culture applications. PMID:27935982

  4. Probability of the moiré effect in barrier and lenticular autostereoscopic 3D displays.

    PubMed

    Saveljev, Vladimir; Kim, Sung-Kyu

    2015-10-05

    The probability of the moiré effect in LCD displays is estimated as a function of angle based on the experimental data; a theoretical function (node spacing) is proposed basing on the distance between nodes. Both functions are close to each other. The connection between the probability of the moiré effect and the Thomae's function is also found. The function proposed in this paper can be used in the minimization of the moiré effect in visual displays, especially in autostereoscopic 3D displays.

  5. Effects of magnetic ripple on 3D equilibrium and alpha particle confinement in the European DEMO

    NASA Astrophysics Data System (ADS)

    Pfefferlé, D.; Cooper, W. A.; Fasoli, A.; Graves, J. P.

    2016-11-01

    An assessment of alpha particle confinement is performed in the European DEMO reference design. 3D MHD equilibria with nested flux-surfaces and single magnetic axis are obtained with the VMEC free-boundary code, thereby including the plasma response to the magnetic ripple created by the finite number of TF coils. Populations of fusion alphas that are consistent with the equilibrium profiles are evolved until slowing-down with the VENUS-LEVIS orbit code in the guiding-centre approximation. Fast ion losses through the last-closed flux-surface are numerically evaluated with two ripple models: (1) using the 3D equilibrium and (2) algebraically adding the non-axisymmetric ripple perturbation to the 2D equilibrium. By virtue of the small ripple field and its non-resonant nature, both models quantitatively agree. Differences are however noted in the toroidal location of particles losses on the last-closed flux-surface, which in the first case is 3D and in the second not. Superbanana transport, i.e. ripple-well trapping and separatrix crossing, is expected to be the dominant loss mechanism, the strongest effect on alphas being between 100-200 KeV. Above this, stochastic ripple diffusion is responsible for a rather weak loss rate, as the stochastisation threshold is observed numerically to be higher than analytic estimates. The level of ripple in the current 18 TF coil design of the European DEMO is not found to be detrimental to fusion alpha confinement.

  6. GISAXS analysis of 3D nanoparticle assemblies--effect of vertical nanoparticle ordering.

    PubMed

    Vegso, K; Siffalovic, P; Benkovicova, M; Jergel, M; Luby, S; Majkova, E; Capek, I; Kocsis, T; Perlich, J; Roth, S V

    2012-02-03

    We report on grazing-incidence small-angle x-ray scattering (GISAXS) study of 3D nanoparticle arrays prepared by two different methods from colloidal solutions-layer-by-layer Langmuir-Schaefer deposition and spontaneous self-assembling during the solvent evaporation. GISAXS results are evaluated within the distorted wave Born approximation (DWBA) considering the multiple scattering effects and employing a simplified multilayer model to reduce the computing time. In the model, particular layers are represented by nanoparticle chains where the positions of individual nanoparticles are generated following a model of cumulative disorder. The nanoparticle size dispersion is considered as well. Three model cases are distinguished-no shift between the neighboring chains (AA stacking), a shift equal to half of the mean interparticle distance (AB stacking) and random shift between the chains. The first two cases correspond to vertically correlated nanoparticle positions across different chains. A comparison of the experimental GISAXS patterns with the model cases enabled us to distinguish important differences between the 3D arrays prepared by the two methods. In particular, laterally ordered layers without vertical correlation of the nanoparticle positions were found in the nanoparticle multilayers prepared by the Langmuir-Schaefer method. On the other hand, the solvent evaporation under particular conditions produced highly ordered 3D nanoparticle assemblies where both laterally and vertically correlated nanoparticle positions were found.

  7. Effect of background rotation on the evolution of 3D internal gravity wave beams

    NASA Astrophysics Data System (ADS)

    Fan, Boyu; Akylas, T. R.

    2016-11-01

    The effect of background rotation on the 3D propagation of internal gravity wave beams (IGWB) is studied, assuming that variations in the along-beam and transverse directions are of long length scale relative to the beam width. The present study generalizes the asymptotic model of KA (Kataoka & Akylas 2015) who considered the analogous problem in the absence of rotation. It is shown that the role of mean vertical vorticity in the earlier analysis is now taken by the flow mean potential vorticity (MPV). Specifically, 3D variations enable resonant transfer of energy to the flow MPV, resulting in strong nonlinear coupling between a 3D IGWB and its induced mean flow. This coupling mechanism is governed by a system of two nonlinear equations of the same form as those derived in KA. Accordingly, the induced mean flow features a purely inviscid modulational component, as well as a viscous one akin to acoustic streaming; the latter grows linearly with time for a quasi-steady IGWB. On the other hand, owing to background rotation, the induced mean flow in the vicinity of the IGWB is no longer purely horizontal and develops an asymmetric behavior. Supported by NSF.

  8. Relaxation and merging flux ropes and 3D effects in the Reconnection Scaling Experiment at LANL

    NASA Astrophysics Data System (ADS)

    Intrator, T.; Furno, I.; Light, A.; Madziwa-Nussinov, T.; Lapenta, G.; Ricci, P.; Hemsing, E.

    2005-12-01

    Magnetic structures are embedded in astrophysical, space, solar and laboratory plasmas. The dynamics and relaxation of these plasmas can involve flows, changes in topology, magnetic reconnection, plasma heating, and dissipation of magnetic energy. This complex behavior is intrinsically three-dimensional (3D). Current-carrying magnetic flux ropes are the fundamental building blocks for many of these cases. At Los Alamos National Laboratory, we have an experimental realization of this model. The Reconnection Scaling Experiment (RSX) is a unique facility that can create multiple current-carrying flux ropes in an MHD experiment. Plasma guns are used to inject magnetic helicity into plasma columns. We show 3D structure with camera views, along with magnetic, electric, and particle probe data. Experiments in the presence of a strong guide magnetic field (Bz/Brcxn>10) show the formation of a current sheet and electron heating during the coalescence of two flux ropes. Computed simulations of the interactions of two current ropes are shown of that predict many of the experimental characteristics. A density wave structure that propagates opposite to the current is measured in the current sheet with wavelength and speed that are consistent with a kinetic Alfven wave. The current channels acquire angular momentum and rotate about each other developing helical structures, both individually and jointly. Parallel pressure gradients (a 3D effect) appear to be an important term in the Ohm's Law.

  9. The effect of background and illumination on color identification of real, 3D objects

    PubMed Central

    Allred, Sarah R.; Olkkonen, Maria

    2013-01-01

    For the surface reflectance of an object to be a useful cue to object identity, judgments of its color should remain stable across changes in the object's environment. In 2D scenes, there is general consensus that color judgments are much more stable across illumination changes than background changes. Here we investigate whether these findings generalize to real 3D objects. Observers made color matches to cubes as we independently varied both the illumination impinging on the cube and the 3D background of the cube. As in 2D scenes, we found relatively high but imperfect stability of color judgments under an illuminant shift. In contrast to 2D scenes, we found that background had little effect on average color judgments. In addition, variability of color judgments was increased by an illuminant shift and decreased by embedding the cube within a background. Taken together, these results suggest that in real 3D scenes with ample cues to object segregation, the addition of a background may improve stability of color identification. PMID:24273521

  10. Reaching to virtual targets: The oblique effect reloaded in 3-D.

    PubMed

    Kaspiris-Rousellis, Christos; Siettos, Constantinos I; Evdokimidis, Ioannis; Smyrnis, Nikolaos

    2017-02-20

    Perceiving and reproducing direction of visual stimuli in 2-D space produces the visual oblique effect, which manifests as increased precision in the reproduction of cardinal compared to oblique directions. A second cognitive oblique effect emerges when stimulus information is degraded (such as when reproducing stimuli from memory) and manifests as a systematic distortion where reproduced directions close to the cardinal axes deviate toward the oblique, leading to space expansion at cardinal and contraction at oblique axes. We studied the oblique effect in 3-D using a virtual reality system to present a large number of stimuli, covering the surface of an imaginary half sphere, to which subjects had to reach. We used two conditions, one with no delay (no-memory condition) and one where a three-second delay intervened between stimulus presentation and movement initiation (memory condition). A visual oblique effect was observed for the reproduction of cardinal directions compared to oblique, which did not differ with memory condition. A cognitive oblique effect also emerged, which was significantly larger in the memory compared to the no-memory condition, leading to distortion of directional space with expansion near the cardinal axes and compression near the oblique axes on the hemispherical surface. This effect provides evidence that existing models of 2-D directional space categorization could be extended in the natural 3-D space.

  11. Seismic Hazard Maps for Seattle, Washington, Incorporating 3D Sedimentary Basin Effects, Nonlinear Site Response, and Rupture Directivity

    USGS Publications Warehouse

    Frankel, Arthur D.; Stephenson, William J.; Carver, David L.; Williams, Robert A.; Odum, Jack K.; Rhea, Susan

    2007-01-01

    This report presents probabilistic seismic hazard maps for Seattle, Washington, based on over 500 3D simulations of ground motions from scenario earthquakes. These maps include 3D sedimentary basin effects and rupture directivity. Nonlinear site response for soft-soil sites of fill and alluvium was also applied in the maps. The report describes the methodology for incorporating source and site dependent amplification factors into a probabilistic seismic hazard calculation. 3D simulations were conducted for the various earthquake sources that can affect Seattle: Seattle fault zone, Cascadia subduction zone, South Whidbey Island fault, and background shallow and deep earthquakes. The maps presented in this document used essentially the same set of faults and distributed-earthquake sources as in the 2002 national seismic hazard maps. The 3D velocity model utilized in the simulations was validated by modeling the amplitudes and waveforms of observed seismograms from five earthquakes in the region, including the 2001 M6.8 Nisqually earthquake. The probabilistic seismic hazard maps presented here depict 1 Hz response spectral accelerations with 10%, 5%, and 2% probabilities of exceedance in 50 years. The maps are based on determinations of seismic hazard for 7236 sites with a spacing of 280 m. The maps show that the most hazardous locations for this frequency band (around 1 Hz) are soft-soil sites (fill and alluvium) within the Seattle basin and along the inferred trace of the frontal fault of the Seattle fault zone. The next highest hazard is typically found for soft-soil sites in the Duwamish Valley south of the Seattle basin. In general, stiff-soil sites in the Seattle basin exhibit higher hazard than stiff-soil sites outside the basin. Sites with shallow bedrock outside the Seattle basin have the lowest estimated hazard for this frequency band.

  12. Comparison of 3D-OP-OSEM and 3D-FBP reconstruction algorithms for High-Resolution Research Tomograph studies: effects of randoms estimation methods

    NASA Astrophysics Data System (ADS)

    van Velden, Floris H. P.; Kloet, Reina W.; van Berckel, Bart N. M.; Wolfensberger, Saskia P. A.; Lammertsma, Adriaan A.; Boellaard, Ronald

    2008-06-01

    The High-Resolution Research Tomograph (HRRT) is a dedicated human brain positron emission tomography (PET) scanner. Recently, a 3D filtered backprojection (3D-FBP) reconstruction method has been implemented to reduce bias in short duration frames, currently observed in 3D ordinary Poisson OSEM (3D-OP-OSEM) reconstructions. Further improvements might be expected using a new method of variance reduction on randoms (VRR) based on coincidence histograms instead of using the delayed window technique (DW) to estimate randoms. The goal of this study was to evaluate VRR in combination with 3D-OP-OSEM and 3D-FBP reconstruction techniques. To this end, several phantom studies and a human brain study were performed. For most phantom studies, 3D-OP-OSEM showed higher accuracy of observed activity concentrations with VRR than with DW. However, both positive and negative deviations in reconstructed activity concentrations and large biases of grey to white matter contrast ratio (up to 88%) were still observed as a function of scan statistics. Moreover 3D-OP-OSEM+VRR also showed bias up to 64% in clinical data, i.e. in some pharmacokinetic parameters as compared with those obtained with 3D-FBP+VRR. In the case of 3D-FBP, VRR showed similar results as DW for both phantom and clinical data, except that VRR showed a better standard deviation of 6-10%. Therefore, VRR should be used to correct for randoms in HRRT PET studies.

  13. Effect of orthodontic debonding and residual adhesive removal on 3D enamel microroughness

    PubMed Central

    Tomkowski, Robert; Tandecka, Katarzyna; Stepien, Piotr; Szatkiewicz, Tomasz; Sporniak-Tutak, Katarzyna; Grocholewicz, Katarzyna

    2016-01-01

    scale-limited surface). Discussion Confocal laser microscopy allowed 3D surface analysis of enamel surface, avoiding the limitations of contact profilometry. Tungsten carbide burs are the most popular adhesive removing tools, however, the results of the present study indicate, that a one step polisher and finisher as well as Adhesive Residue Remover are less detrimental to the enamel. This is in agreement with a recent study based on direct 3D scanning enamel surface. It proved, that a one-step finisher and polisher as well as Adhesive Residue Remover are characterized by a similar effectiveness in removing residual remnants as tungsten carbide bur, but they remove significantly less enamel. Conclusion Orthodontic debonding and removal of adhesive remnants increases enamel roughness. The smoothest surfaces were achieved using Adhesive Residue Remover, and the roughest using tungsten carbide bur. PMID:27761343

  14. Effects of haptic information on the perception of dynamic 3-D movement.

    PubMed

    Umemura, Hiroyuki

    2014-01-01

    This study examined effects of hand movement on visual perception of 3-D movement. I used an apparatus in which a cursor position in a simulated 3-D space and the position of a stylus on a haptic device could coincide using a mirror. In three experiments, participants touched the center of a rectangle in the visual display with the stylus of the force-feedback device. Then the rectangle's surface stereoscopically either protruded toward a participant or indented away from the participant. Simultaneously, the stylus either pushed back participant's hand, pulled away, or remained static. Visual and haptic information were independently manipulated. Participants judged whether the rectangle visually protruded or dented. Results showed that when the hand was pulled away, subjects were biased to perceive rectangles indented; however, when the hand was pushed back, no effect of haptic information was observed (Experiment 1). This effect persisted even when the cursor position was spatially separated from the hand position (Experiment 2). But, when participants touched an object different from the visual stimulus, this effect disappeared (Experiment 3). These results suggest that the visual system tried to integrate the dynamic visual and haptic information when they coincided cognitively, and the effect of haptic information on visually perceived depth was direction-dependent.

  15. An electrically conductive 3D scaffold based on a nonwoven web of poly(L-lactic acid) and conductive poly(3,4-ethylenedioxythiophene).

    PubMed

    Niu, Xufeng; Rouabhia, Mahmoud; Chiffot, Nicolas; King, Martin W; Zhang, Ze

    2015-08-01

    This study was to demonstrate that an extremely thin coating of poly(3,4-ethylenedioxythiophene) (PEDOT) on nonwoven microfibrous poly(l-lactic acid) (PLLA) web is of sufficient electrical conductivity and stability in aqueous environment to sustain electrical stimulation (ES) to cultured human skin fibroblasts. The PEDOT imparted the web a surface resistivity of approximately 0.1 KΩ/square without altering the web morphology. X-ray photoelectron spectroscopy demonstrated that the surface chemistry of the PLLA/PEDOT is characteristic of both PLLA and PEDOT. The PEDOT-coated web also showed higher hydrophilicity, lower glass transition temperature and unchanged fiber crystallinity and thermal stability compared with the PLLA web. The addition of PEDOT to the web marginally increased the web's tensile strength and lowered the elongation. An electrical stability test showed that the PLLA/PEDOT structure was more stable than a polypyrrole treated PLLA fabric, showing only a slow deterioration in conductivity when exposed to culture medium. The cytotoxicity test showed that the PLLA/PEDOT scaffold was not cytotoxic and supported human dermal fibroblast adhesion, migration, and proliferation. Preliminary ES experiments have demonstrated that this conductive web mediated effective ES to fibroblasts. Therefore, this new conductive biodegradable scaffold may be used to electrically modulate cellular activity and tissue regeneration.

  16. Effects of a weakly 3-D equilibrium on ideal magnetohydrodynamic instabilities

    SciTech Connect

    Hegna, C. C.

    2014-07-15

    The effect of a small three-dimensional equilibrium distortion on an otherwise axisymmetric configuration is shown to be destabilizing to ideal magnetohydrodynamic modes. The calculations assume that the 3-D fields are weak and that shielding physics is present so that no islands appear in the resulting equilibrium. An eigenfunction that has coupled harmonics of different toroidal mode number is constructed using a perturbation approach. The theory is applied to the case of tokamak H-modes with shielded resonant magnetic perturbations (RMPs) present indicating RMPs can be destabilizing to intermediate-n peeling-ballooning modes.

  17. Global existence and asymptotic behavior for the 3D compressible Navier-Stokes equations without heat conductivity in a bounded domain

    NASA Astrophysics Data System (ADS)

    Wu, Guochun

    2017-01-01

    In this paper, we investigate the global existence and uniqueness of strong solutions to the initial boundary value problem for the 3D compressible Navier-Stokes equations without heat conductivity in a bounded domain with slip boundary. The global existence and uniqueness of strong solutions are obtained when the initial data is near its equilibrium in H2 (Ω). Furthermore, the exponential convergence rates of the pressure and velocity are also proved by delicate energy methods.

  18. Effect of Frictions on the Ballistic Performance of a 3D Warp Interlock Fabric: Numerical Analysis

    NASA Astrophysics Data System (ADS)

    Ha-Minh, Cuong; Boussu, François; Kanit, Toufik; Crépin, David; Imad, Abdellatif

    2012-06-01

    3D interlock woven fabrics are promising materials to replace the 2D structures in the field of ballistic protection. The structural complexity of this material caused many difficulties in numerical modeling. This paper presents a new tool that permits to generate a geometry model of any woven fabric, then, mesh this model in shell or solid elements, and apply the mechanical properties of yarns to them. The tool shows many advantages over existing software. It is very handy in use with an organization of the functions in menu and using a graphic interface. It can describe correctly the geometry of all textile woven fabrics. With this tool, the orientation of the local axes of finite elements following the yarn direction facilitates defining the yarn mechanical properties in a numerical model. This tool can be largely applied because it is compatible with popular finite element codes such as Abaqus, Ansys, Radioss etc. Thanks to this tool, a finite element model was carried out to describe a ballistic impact on a 3D warp interlock Kevlar KM2® fabric. This work focuses on studying the effect of friction onto the ballistic impact behavior of this textile interlock structure. Results showed that the friction among yarns affects considerably on the impact behavior of this fabric. The effect of the friction between projectile and yarn is less important. The friction plays an important role in keeping the fabric structural stability during the impact event. This phenomenon explained why the projectile is easier to penetrate this 3D warp interlock fabric in the no-friction case. This result also indicates that the ballistic performance of the interlock woven fabrics can be improved by using fibers with great friction coefficients.

  19. Effect of Damping and Yielding on the Seismic Response of 3D Steel Buildings with PMRF

    PubMed Central

    Haldar, Achintya; Rodelo-López, Ramon Eduardo; Bojórquez, Eden

    2014-01-01

    The effect of viscous damping and yielding, on the reduction of the seismic responses of steel buildings modeled as three-dimensional (3D) complex multidegree of freedom (MDOF) systems, is studied. The reduction produced by damping may be larger or smaller than that of yielding. This reduction can significantly vary from one structural idealization to another and is smaller for global than for local response parameters, which in turn depends on the particular local response parameter. The uncertainty in the estimation is significantly larger for local response parameter and decreases as damping increases. The results show the limitations of the commonly used static equivalent lateral force procedure where local and global response parameters are reduced in the same proportion. It is concluded that estimating the effect of damping and yielding on the seismic response of steel buildings by using simplified models may be a very crude approximation. Moreover, the effect of yielding should be explicitly calculated by using complex 3D MDOF models instead of estimating it in terms of equivalent viscous damping. The findings of this paper are for the particular models used in the study. Much more research is needed to reach more general conclusions. PMID:25097892

  20. Effects of scanning orientation on outlier formation in 3D laser scanning of reflective surfaces

    NASA Astrophysics Data System (ADS)

    Wang, Yutao; Feng, Hsi-Yung

    2016-06-01

    Inspecting objects with reflective surfaces using 3D laser scanning is a demanded but challenging part inspection task due to undesirable specular reflections, which produce extensive outliers in the scanned point cloud. These outliers need to be removed in order to alleviate subsequent data processing issues. Many existing automatic outlier removal methods do not detect outliers according to the outlier formation properties. As a result, these methods only offer limited capabilities in removing extensive and complex outliers from scanning objects with reflective surfaces. This paper reports an empirical study which experimentally investigates the outlier formation characteristics in relation to the scanning orientation of the laser probe. The objective is to characterize the scanning orientation effects on outlier formation in order to facilitate the development of an effective outlier detection and removal method. Such an experimental investigation was hardly done before. It has been found in this work that scanning orientation can directly affect outlier extensity and occurrence in 3D laser scanning. A general guidance on proper scan path planning can then be provided with an aim to reduce the occurrence of outliers. Further, the observed dependency of outlier formation on scanning orientation can be exploited to facilitate effective and automatic outlier detection and removal.

  1. Effect of damping and yielding on the seismic response of 3D steel buildings with PMRF.

    PubMed

    Reyes-Salazar, Alfredo; Haldar, Achintya; Rodelo-López, Ramon Eduardo; Bojórquez, Eden

    2014-01-01

    The effect of viscous damping and yielding, on the reduction of the seismic responses of steel buildings modeled as three-dimensional (3D) complex multidegree of freedom (MDOF) systems, is studied. The reduction produced by damping may be larger or smaller than that of yielding. This reduction can significantly vary from one structural idealization to another and is smaller for global than for local response parameters, which in turn depends on the particular local response parameter. The uncertainty in the estimation is significantly larger for local response parameter and decreases as damping increases. The results show the limitations of the commonly used static equivalent lateral force procedure where local and global response parameters are reduced in the same proportion. It is concluded that estimating the effect of damping and yielding on the seismic response of steel buildings by using simplified models may be a very crude approximation. Moreover, the effect of yielding should be explicitly calculated by using complex 3D MDOF models instead of estimating it in terms of equivalent viscous damping. The findings of this paper are for the particular models used in the study. Much more research is needed to reach more general conclusions.

  2. Quantum anomalous Hall effect and tunable topological states in 3d transition metals doped silicene.

    PubMed

    Zhang, Xiao-Long; Liu, Lan-Feng; Liu, Wu-Ming

    2013-10-09

    Silicene is an intriguing 2D topological material which is closely analogous to graphene but with stronger spin orbit coupling effect and natural compatibility with current silicon-based electronics industry. Here we demonstrate that silicene decorated with certain 3d transition metals (Vanadium) can sustain a stable quantum anomalous Hall effect using both analytical model and first-principles Wannier interpolation. We also predict the quantum valley Hall effect and electrically tunable topological states could be realized in certain transition metal doped silicene where the energy band inversion occurs. Our findings provide new scheme for the realization of quantum anomalous Hall effect and platform for electrically controllable topological states which are highly desirable for future nanoelectronics and spintronics application.

  3. Seismic Response of 3D Steel Buildings considering the Effect of PR Connections and Gravity Frames

    PubMed Central

    Haldar, Achintya; López-Barraza, Arturo; Rivera-Salas, J. Luz

    2014-01-01

    The nonlinear seismic responses of 3D steel buildings with perimeter moment resisting frames (PMRF) and interior gravity frames (IGF) are studied explicitly considering the contribution of the IGF. The effect on the structural response of the stiffness of the beam-to-column connections of the IGF, which is usually neglected, is also studied. It is commonly believed that the flexibility of shear connections is negligible and that 2D models can be used to properly represent 3D real structures. The results of the study indicate, however, that the moments developed on columns of IGF can be considerable and that modeling buildings as plane frames may result in very conservative designs. The contribution of IGF to the lateral structural resistance may be significant. The contribution increases when their connections are assumed to be partially restrained (PR). The incremented participation of IGF when the stiffness of their connections is considered helps to counteract the no conservative effect that results in practice when lateral seismic loads are not considered in IGF while designing steel buildings with PMRF. Thus, if the structural system under consideration is used, the three-dimensional model should be used in seismic analysis and the IGF and the stiffness of their connections should be considered as part of the lateral resistance system. PMID:24995357

  4. Seismic response of 3D steel buildings considering the effect of PR connections and gravity frames.

    PubMed

    Reyes-Salazar, Alfredo; Bojórquez, Edén; Haldar, Achintya; López-Barraza, Arturo; Rivera-Salas, J Luz

    2014-01-01

    The nonlinear seismic responses of 3D steel buildings with perimeter moment resisting frames (PMRF) and interior gravity frames (IGF) are studied explicitly considering the contribution of the IGF. The effect on the structural response of the stiffness of the beam-to-column connections of the IGF, which is usually neglected, is also studied. It is commonly believed that the flexibility of shear connections is negligible and that 2D models can be used to properly represent 3D real structures. The results of the study indicate, however, that the moments developed on columns of IGF can be considerable and that modeling buildings as plane frames may result in very conservative designs. The contribution of IGF to the lateral structural resistance may be significant. The contribution increases when their connections are assumed to be partially restrained (PR). The incremented participation of IGF when the stiffness of their connections is considered helps to counteract the no conservative effect that results in practice when lateral seismic loads are not considered in IGF while designing steel buildings with PMRF. Thus, if the structural system under consideration is used, the three-dimensional model should be used in seismic analysis and the IGF and the stiffness of their connections should be considered as part of the lateral resistance system.

  5. Effects of 3D geometries on cellular gradient sensing and polarization

    NASA Astrophysics Data System (ADS)

    Spill, Fabian; Andasari, Vivi; Mak, Michael; Kamm, Roger D.; Zaman, Muhammad H.

    2016-06-01

    During cell migration, cells become polarized, change their shape, and move in response to various internal and external cues. Cell polarization is defined through the spatio-temporal organization of molecules such as PI3K or small GTPases, and is determined by intracellular signaling networks. It results in directional forces through actin polymerization and myosin contractions. Many existing mathematical models of cell polarization are formulated in terms of reaction-diffusion systems of interacting molecules, and are often defined in one or two spatial dimensions. In this paper, we introduce a 3D reaction-diffusion model of interacting molecules in a single cell, and find that cell geometry has an important role affecting the capability of a cell to polarize, or change polarization when an external signal changes direction. Our results suggest a geometrical argument why more roundish cells can repolarize more effectively than cells which are elongated along the direction of the original stimulus, and thus enable roundish cells to turn faster, as has been observed in experiments. On the other hand, elongated cells preferentially polarize along their main axis even when a gradient stimulus appears from another direction. Furthermore, our 3D model can accurately capture the effect of binding and unbinding of important regulators of cell polarization to and from the cell membrane. This spatial separation of membrane and cytosol, not possible to capture in 1D or 2D models, leads to marked differences of our model from comparable lower-dimensional models.

  6. Conducting effective tailgate trainings.

    PubMed

    Harrington, David; Materna, Barbara; Vannoy, Jim; Scholz, Peter

    2009-07-01

    The California Department of Health Services' Occupational Health Branch and others have identified the construction industry as being at high risk for injuries, illnesses, and fatalities. Effective tailgate trainings (brief job site safety meetings) can be a powerful tool to promote hazard awareness and safe work practices. The authors found that many contractors and supervisors conducted ineffective tailgate trainings. They developed the BuildSafe California Project to assist contractors to have more effective programs by holding 25 training-of-trainers sessions reaching 1,525 participants. The needs assessment, intervention, and evaluation results from the first 18 trainings are presented. Eighty-six percent of the participants found the program "very helpful." Participants used the materials and made improvements in the quality and frequency of trainings. Supervisors must be skilled at conducting tailgate trainings as part of their responsibilities. There is a serious need to provide more culturally appropriate safety training in a workforce increasingly made up of Latino workers.

  7. Are There Side Effects to Watching 3D Movies? A Prospective Crossover Observational Study on Visually Induced Motion Sickness

    PubMed Central

    Solimini, Angelo G.

    2013-01-01

    Background The increasing popularity of commercial movies showing three dimensional (3D) images has raised concern about possible adverse side effects on viewers. Methods and Findings A prospective carryover observational study was designed to assess the effect of exposure (3D vs. 2D movie views) on self reported symptoms of visually induced motion sickness. The standardized Simulator Sickness Questionnaire (SSQ) was self administered on a convenience sample of 497 healthy adult volunteers before and after the vision of 2D and 3D movies. Viewers reporting some sickness (SSQ total score>15) were 54.8% of the total sample after the 3D movie compared to 14.1% of total sample after the 2D movie. Symptom intensity was 8.8 times higher than baseline after exposure to 3D movie (compared to the increase of 2 times the baseline after the 2D movie). Multivariate modeling of visually induced motion sickness as response variables pointed out the significant effects of exposure to 3D movie, history of car sickness and headache, after adjusting for gender, age, self reported anxiety level, attention to the movie and show time. Conclusions Seeing 3D movies can increase rating of symptoms of nausea, oculomotor and disorientation, especially in women with susceptible visual-vestibular system. Confirmatory studies which include examination of clinical signs on viewers are needed to pursue a conclusive evidence on the 3D vision effects on spectators. PMID:23418530

  8. Effects of Verbal Components in 3D Talking-Head on Pronunciation Learning among Non-Native Speakers

    ERIC Educational Resources Information Center

    Ali, Ahmad Zamzuri Mohamad; Segaran, Kogilathah; Hoe, Tan Wee

    2015-01-01

    This study was designed to investigate the benefit of inclusion of various verbal elements in 3D talking-head on pronunciation learning among non-native speakers. In particular, the study examines the effects of three different multimedia presentation strategies in 3D talking-head Mobile-Assisted-Language-Learning (MALL) on the learning…

  9. The Effects of 3D Computer Modelling on Conceptual Change about Seasons and Phases of the Moon

    ERIC Educational Resources Information Center

    Kucukozer, Huseyin

    2008-01-01

    In this study, prospective science teachers' misconceptions about the seasons and the phases of the Moon were determined, and then the effects of 3D computer modelling on their conceptual changes were investigated. The topics were covered in two classes with a total of 76 students using a predict-observe-explain strategy supported by 3D computer…

  10. Evaluation of the Effectiveness of 3D Vascular Stereoscopic Models in Anatomy Instruction for First Year Medical Students

    ERIC Educational Resources Information Center

    Cui, Dongmei; Wilson, Timothy D.; Rockhold, Robin W.; Lehman, Michael N.; Lynch, James C.

    2017-01-01

    The head and neck region is one of the most complex areas featured in the medical gross anatomy curriculum. The effectiveness of using three-dimensional (3D) models to teach anatomy is a topic of much discussion in medical education research. However, the use of 3D stereoscopic models of the head and neck circulation in anatomy education has not…

  11. Modeling the effects of 3-D slab geometry and oblique subduction on subduction zone thermal structure

    NASA Astrophysics Data System (ADS)

    Wada, I.; Wang, K.; He, J.

    2013-12-01

    In this study, we revisit the effects of along-strike variation in slab geometry and oblique subduction on subduction zone thermal structures. Along-strike variations in slab dip cause changes in the descending rate of the slab and generate trench-parallel pressure gradients that drive trench-parallel mantle flow (e.g., Kneller and van Keken, 2007). Oblique subduction also drives trench-parallel mantle flow. In this study, we use a finite element code PGCtherm3D and examine a range of generic subduction geometries and parameters to investigate the effects of the above two factors. This exercise is part of foundational work towards developing detailed 3-D thermal models for NE Japan, Nankai, and Cascadia to better constrain their 3-D thermal structures and to understand the role of temperature in controlling metamorphic, seismogenic, and volcanic processes. The 3-D geometry of the subducting slabs in the forearc and arc regions are well delineated at these three subduction zones. Further, relatively large compilations of surface heat flow data at these subduction zones make them excellent candidates for this study. At NE Japan, a megathrust earthquake occurred on March 11, 2011; at Nankai and Cascadia, there has been a great effort to constrain the scale of the next subduction thrust earthquake for the purpose of disaster prevention. Temperature influences the slip behavior of subduction faults by (1) affecting the rheology of the interface material and (2) controlling dehydration reactions, which can lead to elevated pore fluid pressure. Beyond the depths of subduction thrust earthquakes, the thermal structure is affected strongly by the pattern of mantle wedge flow. This flow is driven by viscous coupling between the subducting slab and the overriding mantle, and it brings in hot flowing mantle into the wedge. The trench-ward (up-dip) extent of the slab-mantle coupling is thus a key factor that controls the thermal structure. Slab-mantle decoupling at shallow

  12. The cross-correlation between 3D cosmic shear and the integrated Sachs-Wolfe effect

    NASA Astrophysics Data System (ADS)

    Zieser, Britta; Merkel, Philipp M.

    2016-06-01

    We present the first calculation of the cross-correlation between 3D cosmic shear and the integrated Sachs-Wolfe (iSW) effect. Both signals are combined in a single formalism, which permits the computation of the full covariance matrix. In order to avoid the uncertainties presented by the non-linear evolution of the matter power spectrum and intrinsic alignments of galaxies, our analysis is restricted to large scales, i.e. multipoles below ℓ = 1000. We demonstrate in a Fisher analysis that this reduction compared to other studies of 3D weak lensing extending to smaller scales is compensated by the information that is gained if the additional iSW signal and in particular its cross-correlation with lensing data are considered. Given the observational standards of upcoming weak-lensing surveys like Euclid, marginal errors on cosmological parameters decrease by 10 per cent compared to a cosmic shear experiment if both types of information are combined without a cosmic wave background (CMB) prior. Once the constraining power of CMB data is added, the improvement becomes marginal.

  13. Characterizing the effects of droplines on target acquisition performance on a 3-D perspective display

    NASA Technical Reports Server (NTRS)

    Liao, Min-Ju; Johnson, Walter W.

    2004-01-01

    The present study investigated the effects of droplines on target acquisition performance on a 3-D perspective display in which participants were required to move a cursor into a target cube as quickly as possible. Participants' performance and coordination strategies were characterized using both Fitts' law and acquisition patterns of the 3 viewer-centered target display dimensions (azimuth, elevation, and range). Participants' movement trajectories were recorded and used to determine movement times for acquisitions of the entire target and of each of its display dimensions. The goodness of fit of the data to a modified Fitts function varied widely among participants, and the presence of droplines did not have observable impacts on the goodness of fit. However, droplines helped participants navigate via straighter paths and particularly benefited range dimension acquisition. A general preference for visually overlapping the target with the cursor prior to capturing the target was found. Potential applications of this research include the design of interactive 3-D perspective displays in which fast and accurate selection and manipulation of content residing at multiple ranges may be a challenge.

  14. Effects of extracellular fiber architecture on cell membrane shear stress in a 3D fibrous matrix.

    PubMed

    Pedersen, John A; Boschetti, Federica; Swartz, Melody A

    2007-01-01

    Interstitial fluid flow has been shown to affect the organization and behavior of cells in 3D environments in vivo and in vitro, yet the forces driving such responses are not clear. Due to the complex architecture of the extracellular matrix (ECM) and the difficulty of measuring fluid flow near cells embedded in it, the levels of shear stress experienced by cells in this environment are typically estimated using bulk-averaged matrix parameters such as hydraulic permeability. While this is useful for estimating average stresses, it cannot yield insight into how local matrix fiber architecture-which is cell-controlled in the immediate pericellular environment-affects the local stresses imposed on the cell surface. To address this, we used computational fluid dynamics to study flow through an idealized mesh constructed of a cubic lattice of fibers simulating a typical in vitro collagen gel. We found that, in such high porosity matrices, the fibers strongly affect the flow fields near the cell, with peak shear stresses up to five times higher than those predicted by the Brinkman equation. We also found that minor remodeling of the fibers near the cell surface had major effects on the shear stress profile on the cell. These findings demonstrate the importance of fiber architecture to the fluid forces on a cell embedded in a 3D matrix, and also show how small modifications in the local ECM can lead to large changes in the mechanical environment of the cell.

  15. Effects of Matrix Alignment and Mechanical Constraints on Cellular Behavior in 3D Engineered Microtissues

    NASA Astrophysics Data System (ADS)

    Bose, Prasenjit; Eyckmans, Jeroen; Chen, Christopher; Reich, Daniel

    The adhesion of cells to the extracellular matrix (ECM) plays a crucial role in a variety of cellular functions. The main building blocks of the ECM are 3D networks of fibrous proteins whose structure and alignments varies with tissue type. However, the impact of ECM alignment on cellular behaviors such as cell adhesion, spreading, extension and mechanics remains poorly understood. We present results on the development of a microtissue-based system that enables control of the structure, orientation, and degree of fibrillar alignment in 3D fibroblast-populated collagen gels. The tissues self-assemble from cell-laden collagen gels placed in micro-fabricated wells containing sets of elastic pillars. The contractile action of the cells leads to controlled alignment of the fibrous collagen, depending on the number and location of the pillars in each well. The pillars are elastic, and are utilized to measure the contractile forces of the microtissues, and by incorporating magnetic material in selected pillars, time-varying forces can be applied to the tissues for dynamic stimulation and measurement of mechanical properties. Results on the effects of varying pillar shape, spacing, location, and stiffness on microtissue organization and contractility will be presented. This work is supported by NSF CMMI-1463011.

  16. Salinity effects on cracking morphology and dynamics in 3-D desiccating clays

    NASA Astrophysics Data System (ADS)

    DeCarlo, Keita F.; Shokri, Nima

    2014-04-01

    Saline conditions induce not only chemical but physical changes in swelling clays, and have a significant influence on the crack dynamics and morphology of desiccating clays. In this study, we used X-ray microtomography to experimentally investigate the effects of sodium chloride on the morphology and dynamics of desiccation cracks in three-dimensional mixtures of sand-bentonite slurry under varying rheological conditions. Rectangular glass containers were packed with slurries of different salt concentrations, with the top boundary exposed to air for evaporation. The growth and propagation of the cracking network that subsequently formed was visualized in 3-D at multiple intervals. The characterization of cracking and branching behavior shows a high extent of localized surficial crack networks at low salinity, with a transition to less extensive but more centralized crack networks with increased salinity. The observed behavior was described in the context of the physicochemical properties of the montmorillonite clay, where shifts from an "entangled" (large platelet spacing, small pore structure) to a "stacked" (small platelet spacing, open pore structure) network influence fluid distribution and thus extent of cracking and branching behavior. This is further corroborated by vertical profiles of water distribution, which shows localized desiccation fronts that shift to uniform desaturation with increasing salt concentration. Our results provide new insights regarding the formation, dynamics, and patterns of desiccation cracks formed during evaporation from 3-D saline clay structures, which will be useful in hydrological applications including water management, land surface evaporation, and subsurface contaminant transport.

  17. The Effect of Underwater Imagery Radiometry on 3d Reconstruction and Orthoimagery

    NASA Astrophysics Data System (ADS)

    Agrafiotis, P.; Drakonakis, G. I.; Georgopoulos, A.; Skarlatos, D.

    2017-02-01

    The work presented in this paper investigates the effect of the radiometry of the underwater imagery on automating the 3D reconstruction and the produced orthoimagery. Main aim is to investigate whether pre-processing of the underwater imagery improves the 3D reconstruction using automated SfM - MVS software or not. Since the processing of images either separately or in batch is a time-consuming procedure, it is critical to determine the necessity of implementing colour correction and enhancement before the SfM - MVS procedure or directly to the final orthoimage when the orthoimagery is the deliverable. Two different test sites were used to capture imagery ensuring different environmental conditions, depth and complexity. Three different image correction methods are applied: A very simple automated method using Adobe Photoshop, a developed colour correction algorithm using the CLAHE (Zuiderveld, 1994) method and an implementation of the algorithm described in Bianco et al., (2015). The produced point clouds using the initial and the corrected imagery are then being compared and evaluated.

  18. Global 3-D imaging of mantle electrical conductivity based on inversion of observatory C-responses - I. An approach and its verification

    NASA Astrophysics Data System (ADS)

    Kuvshinov, Alexey; Semenov, Alexey

    2012-06-01

    We present a novel frequency-domain inverse solution to recover the 3-D electrical conductivity distribution in the mantle. The solution is based on analysis of local C-responses. It exploits an iterative gradient-type method - limited-memory quasi-Newton method - for minimizing the penalty function consisting of data misfit and regularization terms. The integral equation code is used as a forward engine to calculate responses and data misfit gradients during inversion. An adjoint approach is implemented to compute misfit gradients efficiently. Further improvements in computational load come from parallelizing the scheme with respect to frequencies, and from setting the most time-consuming part of the forward calculations - calculation of Green's tensors - apart from the inversion loop. Convergence, performance, and accuracy of our 3-D inverse solution are demonstrated with a synthetic numerical example. A companion paper applies the strategy set forth here to real data.

  19. Radiation Quality Effects on Transcriptome Profiles in 3-D Cultures After Charged Particle Irradiation

    NASA Technical Reports Server (NTRS)

    Patel, Zarana S.; Kidane, Yared H.; Huff, Janice L.

    2014-01-01

    In this work, we evaluated the differential effects of low- and high-LET radiation on 3-D organotypic cultures in order to investigate radiation quality impacts on gene expression and cellular responses. Current risk models for assessment of space radiation-induced cancer have large uncertainties because the models for adverse health effects following radiation exposure are founded on epidemiological analyses of human populations exposed to low-LET radiation. Reducing these uncertainties requires new knowledge on the fundamental differences in biological responses (the so-called radiation quality effects) triggered by heavy ion particle radiation versus low-LET radiation associated with Earth-based exposures. In order to better quantify these radiation quality effects in biological systems, we are utilizing novel 3-D organotypic human tissue models for space radiation research. These models hold promise for risk assessment as they provide a format for study of human cells within a realistic tissue framework, thereby bridging the gap between 2-D monolayer culture and animal models for risk extrapolation to humans. To identify biological pathway signatures unique to heavy ion particle exposure, functional gene set enrichment analysis (GSEA) was used with whole transcriptome profiling. GSEA has been used extensively as a method to garner biological information in a variety of model systems but has not been commonly used to analyze radiation effects. It is a powerful approach for assessing the functional significance of radiation quality-dependent changes from datasets where the changes are subtle but broad, and where single gene based analysis using rankings of fold-change may not reveal important biological information.

  20. Trehalose effectiveness as a cryoprotectant in 2D and 3D cell cultures of human embryonic kidney cells.

    PubMed

    Hara, Jared; Tottori, Jordan; Anders, Megan; Dadhwal, Smritee; Asuri, Prashanth; Mobed-Miremadi, Maryam

    2017-05-01

    Post cryopreservation viability of human embryonic kidney (HEK) cells under two-dimensional (2D) and three-dimensional (3D) culture conditions was studied using trehalose as the sole cryoprotective agent. An L9 (3(4)) Taguchi design was used to optimize the cryoprotection cocktail seeding process prior to slow-freezing with the specific aim of maximizing cell viability measured 7 days post thaw, using the combinatorial cell viability and in-vitro cytotoxicity WST assay. At low (200 mM) and medium (800 mM) levels of trehalose concentration, encapsulation in alginate offered a greater protection to cryopreservation. However, at the highest trehalose concentration (1200 mM) and in the absence of the pre-incubation step, there was no statistical difference at the 95% CI (p = 0.0212) between the viability of the HEK cells under 2D and 3D culture conditions estimated to be 17.9 ± 4.6% and 14.0 ± 3.6%, respectively. A parallel comparison between cryoprotective agents conducted at the optimal levels of the L9 study, using trehalose, dimethylsulfoxide and glycerol in alginate microcapsules yielded a viability of 36.0 ± 7.4% for trehalose, in average 75% higher than the results associated with the other two cell membrane-permeating compounds. In summary, the effectiveness of trehalose has been demonstrated by the fact that 3D cell cultures can readily be equilibrated with trehalose before cryopreservation, thus mitigating the cytotoxic effects of glycerol and dimethylsulfoxide.

  1. Cardiac-induced physiological noise in 3D gradient echo brain imaging: Effect of k -space sampling scheme

    NASA Astrophysics Data System (ADS)

    Kristoffersen, Anders; Goa, Pål Erik

    2011-09-01

    The physiological noise in 3D image acquisition is shown to depend strongly on the sampling scheme. Five sampling schemes are considered: Linear, Centric, Segmented, Random and Tuned. Tuned acquisition means that data acquisition at k-space positions k and - k are separated with a specific time interval. We model physiological noise as a periodic temporal oscillation with arbitrary spatial amplitude in the physical object and develop a general framework to describe how this is rendered in the reconstructed image. Reconstructed noise can be decomposed in one component that is in phase with the signal (parallel) and one that is 90° out of phase (orthogonal). Only the former has a significant influence on the magnitude of the signal. The study focuses on fMRI using 3D EPI. Each k-space plane is acquired in a single shot in a time much shorter than the period of the physiological noise. The above mentioned sampling schemes are applied in the slow k-space direction and noise propagates almost exclusively in this direction. The problem then, is effectively one-dimensional. Numerical simulations and analytical expressions are presented. 3D noise measurements and 2D measurements with high temporal resolution are conducted. The measurements are performed under breath-hold to isolate the effect of cardiac-induced pulsatile motion. We compare the time-course stability of the sampling schemes and the extent to which noise propagates from a localized source into other parts of the imaging volume. Tuned and Linear acquisitions perform better than Centric, Segmented and Random.

  2. Effects of 3D Toroidally Asymmetric Magnetic Field on Tokamak Magnetic Surfaces

    NASA Astrophysics Data System (ADS)

    Lao, L. L.

    2005-10-01

    The effects of 3D error magnetic field on magnetic surfaces are investigated using the DIII-D internal coils (I-Coils). Slowly rotating n=1 traveling waves at 5 Hz and various amplitudes were applied to systematically perturb the edge surfaces by programming the I-Coil currents. The vertical separatrix location difference between EFIT magnetic reconstructions that assumes toroidal symmetry and Thomson scattering Te measurements responds in phase to the applied perturbed field. The oscillation amplitudes increase with the strength of the applied field but are much smaller than those expected from the applied field alone. The results indicate that plasma response is important. Various plasma response models based on results from the MHD codes MARS and GATO are being developed and compared to the experimental observations. To more accurately evaluate the effects of magnetic measurement errors, a new form of the magnetic uncertainty matrix is also being implemented into EFIT. Details will be presented.

  3. 3D viscosity maps for Greenland and effect on GRACE mass balance estimates

    NASA Astrophysics Data System (ADS)

    van der Wal, Wouter; Xu, Zheng

    2016-04-01

    The GRACE satellite mission measures mass loss of the Greenland ice sheet. To correct for glacial isostatic adjustment numerical models are used. Although generally found to be a small signal, the full range of possible GIA models has not been explored yet. In particular, low viscosities due to a wet mantle and high temperatures due to the nearby Iceland hotspot could have a significant effect on GIA gravity rates. The goal of this study is to present a range of possible viscosity maps, and investigate the effect on GRACE mass balance estimates. Viscosity is derived using flow laws for olivine. Mantle temperature is computed from global seismology models, based on temperature derivatives for different mantle compositions. An indication for grain sizes is obtained by xenolith findings at a few locations. We also investigate the weakening effect of the presence of melt. To calculate gravity rates, we use a finite-element GIA model with the 3D viscosity maps and the ICE-5G loading history. GRACE mass balances for mascons in Greenland are derived with a least-squares inversion, using separate constraints for the inland and coastal areas in Greenland. Biases in the least-squares inversion are corrected using scale factors estimated from a simulation based on a surface mass balance model (Xu et al., submitted to The Cryosphere). Model results show enhanced gravity rates in the west and south of Greenland with 3D viscosity maps, compared to GIA models with 1D viscosity. The effect on regional mass balance is up to 5 Gt/year. Regional low viscosity can make present-day gravity rates sensitivity to ice thickness changes in the last decades. Therefore, an improved ice loading history for these time scales is needed.

  4. Controlled 3D Assembly of Graphene Sheets to Build Conductive, Chemically Selective and Shape-Responsive Materials.

    PubMed

    Woltornist, Steven J; Varghese, Deepthi; Massucci, Daniel; Cao, Zhen; Dobrynin, Andrey V; Adamson, Douglas H

    2017-03-06

    Driven by the surface activity of graphene, electrically conductive elastomeric foams have been synthesized by the controlled reassembly of graphene sheets; from their initial stacked morphology, as found in graphite, to a percolating network of exfoliated sheets, defining hollow spheres. This network creates a template for the formation of composite foams, whose swelling behavior is sensitive to the composition of the solvent, and whose electrical resistance is sensitive to physical deformation. The self-assembly of graphene sheets is driven thermodynamically, as graphite is found to act as a 2D surfactant and is spread at high-energy interfaces. This spreading, or exfoliation, of graphite at an oil/water interface stabilizes water-in-oil emulsions, without the need for added surfactants or chemical modification of the graphene. Using a monomer such as butyl acrylate for the emulsion's oil phase, elastomeric foams are created by polymerizing the continuous oil phase. Removal of the aqueous phase then results in robust, conductive, porous, and inexpensive composites, with potential applications in energy storage, filtration, and sensing.

  5. Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time

    PubMed Central

    Baek, NamHuk; Seo, Ok Won; Kim, MinSung; Hulme, John; An, Seong Soo A

    2016-01-01

    Recently, increasing numbers of cell culture experiments with 3D spheroids presented better correlating results in vivo than traditional 2D cell culture systems. 3D spheroids could offer a simple and highly reproducible model that would exhibit many characteristics of natural tissue, such as the production of extracellular matrix. In this paper numerous cell lines were screened and selected depending on their ability to form and maintain a spherical shape. The effects of increasing concentrations of doxorubicin (DXR) on the integrity and viability of the selected spheroids were then measured at regular intervals and in real-time. In total 12 cell lines, adenocarcinomic alveolar basal epithelial (A549), muscle (C2C12), prostate (DU145), testis (F9), pituitary epithelial-like (GH3), cervical cancer (HeLa), HeLa contaminant (HEp2), embryo (NIH3T3), embryo (PA317), neuroblastoma (SH-SY5Y), osteosarcoma U2OS, and embryonic kidney cells (293T), were screened. Out of the 12, 8 cell lines, NIH3T3, C2C12, 293T, SH-SY5Y, A549, HeLa, PA317, and U2OS formed regular spheroids and the effects of DXR on these structures were measured at regular intervals. Finally, 5 cell lines, A549, HeLa, SH-SY5Y, U2OS, and 293T, were selected for real-time monitoring and the effects of DXR treatment on their behavior were continuously recorded for 5 days. A potential correlation regarding the effects of DXR on spheroid viability and ATP production was measured on days 1, 3, and 5. Cytotoxicity of DXR seemed to occur after endocytosis, since the cellular activities and ATP productions were still viable after 1 day of the treatment in all spheroids, except SH-SY5Y. Both cellular activity and ATP production were halted 3 and 5 days from the start of the treatment in all spheroids. All cell lines maintained their spheroid shape, except SHSY-5, which behaved in an unpredictable manner when exposed to toxic concentrations of DXR. Cytotoxic effects of DXR towards SH-SY5Y seemed to cause degradation of

  6. Residual lens effects in 2D mode of auto-stereoscopic lenticular-based switchable 2D/3D displays

    NASA Astrophysics Data System (ADS)

    Sluijter, M.; IJzerman, W. L.; de Boer, D. K. G.; de Zwart, S. T.

    2006-04-01

    We discuss residual lens effects in multi-view switchable auto-stereoscopic lenticular-based 2D/3D displays. With the introduction of a switchable lenticular, it is possible to switch between a 2D mode and a 3D mode. The 2D mode displays conventional content, whereas the 3D mode provides the sensation of depth to the viewer. The uniformity of a display in the 2D mode is quantified by the quality parameter modulation depth. In order to reduce the modulation depth in the 2D mode, birefringent lens plates are investigated analytically and numerically, by ray tracing. We can conclude that the modulation depth in the 2D mode can be substantially decreased by using birefringent lens plates with a perfect index match between lens material and lens plate. Birefringent lens plates do not disturb the 3D performance of a switchable 2D/3D display.

  7. Sensor Spatial Distortion, Visual Latency, and Update Rate Effects on 3D Tracking in Virtual Environments

    NASA Technical Reports Server (NTRS)

    Ellis, S. R.; Adelstein, B. D.; Baumeler, S.; Jense, G. J.; Jacoby, R. H.; Trejo, Leonard (Technical Monitor)

    1998-01-01

    Several common defects that we have sought to minimize in immersing virtual environments are: static sensor spatial distortion, visual latency, and low update rates. Human performance within our environments during large amplitude 3D tracking was assessed by objective and subjective methods in the presence and absence of these defects. Results show that 1) removal of our relatively small spatial sensor distortion had minor effects on the tracking activity, 2) an Adapted Cooper-Harper controllability scale proved the most sensitive subjective indicator of the degradation of dynamic fidelity caused by increasing latency and decreasing frame rates, and 3) performance, as measured by normalized RMS tracking error or subjective impressions, was more markedly influenced by changing visual latency than by update rate.

  8. Assessment of 3D aerodynamic effects on the behaviour of floating wind turbines

    NASA Astrophysics Data System (ADS)

    Manolas, D.; Riziotis, V.; Voutsinas, S.

    2014-12-01

    Current state-of-art models for floating wind turbines are built by merging separate modules addressing the four basic aspects leading to a compound hydro-servo-aero-elastic time domain solver. While current state-of-the-art models differ in many aspects, they all use the blade element momentum (BEM) aerodynamic modelling. Due to its low cost, BEM is the standard choice for design purposes. However the use of BEM entails several semi-empirical corrections and add-ons that need reconsideration and recalibration when new features appear. For floating wind turbines, the effect of the floater motions is such a new feature. In the present paper, this aspect is investigated by comparing BEM based results against 3D free-wake simulations. Deterministic as well as stochastic simulations are presented in pure aerodynamic and full aeroelastic context. It is confirmed that asymmetric inflow originating from yaw misalignment and shear give significant differences reflected on mean values and amplitudes.

  9. 3d Transition Metal Adsorption Induced the valley-polarized Anomalous Hall Effect in Germanene

    PubMed Central

    Zhou, P.; Sun, L. Z.

    2016-01-01

    Based on DFT + U and Berry curvature calculations, we study the electronic structures and topological properties of 3d transition metal (TM) atom (from Ti to Co) adsorbed germanene (TM-germanene). We find that valley-polarized anomalous Hall effect (VAHE) can be realized in germanene by adsorbing Cr, Mn, or Co atoms on its surface. A finite valley Hall voltage can be easily detected in their nanoribbon, which is important for valleytronics devices. Moreover, different valley-polarized current and even reversible valley Hall voltage can be archived by shifting the Fermi energy of the systems. Such versatile features of the systems show potential in next generation electronics devices. PMID:27312176

  10. Characterization of a contaminated wellfield using 3D electrical resistivity tomography implemented with geostatistical, discontinuous boundary, and known conductivity constraints

    SciTech Connect

    Johnson, Timothy C.; Versteeg, Roelof J.; Rockhold, Mark L.; Slater, Lee D.; Ntarlagiannis, Dimitrios; Greenwood, William J.; Zachara, John M.

    2012-09-17

    Continuing advancements in subsurface electrical resistivity tomography (ERT) are giving the method increasing capability for understanding shallow subsurface properties and processes. The inability of ERT imaging data to uniquely resolve subsurface structure and the corresponding need include constraining information remains one of the greatest limitations, and provides one of the greatest opportunities, for further advancing the utility of the method. In this work we describe and demonstrate a method of incorporating constraining information into an ERT imaging algorithm in the form on discontinuous boundaries, known values, and spatial covariance information. We demonstrate the approach by imaging a uranium-contaminated wellfield at the Hanford Site in southwestern Washington State, USA. We incorporate into the algorithm known boundary information and spatial covariance structure derived from the highly resolved near-borehole regions of a regularized ERT inversion. The resulting inversion provides a solution which fits the ERT data (given the estimated noise level), honors the spatial covariance structure throughout the model, and is consistent with known bulk-conductivity discontinuities. The results are validated with core-scale measurements, and display a significant improvement in accuracy over the standard regularized inversion, revealing important subsurface structure known influence flow and transport at the site.

  11. Quantified effects of chromosome-nuclear envelope attachments on 3D organization of chromosomes.

    PubMed

    Kinney, Nicholas Allen; Onufriev, Alexey V; Sharakhov, Igor V

    2015-01-01

    We use a combined experimental and computational approach to study the effects of chromosome-nuclear envelope (Chr-NE) attachments on the 3D genome organization of Drosophila melanogaster (fruit fly) salivary gland nuclei. We consider 3 distinct models: a Null model - without specific Chr-NE attachments, a 15-attachment model - with 15 previously known Chr-NE attachments, and a 48-attachment model - with 15 original and 33 recently identified Chr-NE attachments. The radial densities of chromosomes in the models are compared to the densities observed in 100 experimental images of optically sectioned salivary gland nuclei forming "z-stacks." Most of the experimental z-stacks support the Chr-NE 48-attachment model suggesting that as many as 48 chromosome loci with appreciable affinity for the NE are necessary to reproduce the experimentally observed distribution of chromosome density in fruit fly nuclei. Next, we investigate if and how the presence and the number of Chr-NE attachments affect several key characteristics of 3D genome organization: chromosome territories and gene-gene contacts. This analysis leads to novel insight about the possible role of Chr-NE attachments in regulating the genome architecture. Specifically, we find that model nuclei with more numerous Chr-NE attachments form more distinct chromosome territories and their chromosomes intertwine less frequently. Intra-chromosome and intra-arm contacts are more common in model nuclei with Chr-NE attachments compared to the Null model (no specific attachments), while inter-chromosome and inter-arm contacts are less common in nuclei with Chr-NE attachments. We demonstrate that Chr-NE attachments increase the specificity of long-range inter-chromosome and inter-arm contacts. The predicted effects of Chr-NE attachments are rationalized by intuitive volume vs. surface accessibility arguments.

  12. Effect of voxel size on the accuracy of 3D reconstructions with cone beam CT

    PubMed Central

    Maret, D; Telmon, N; Peters, O A; Lepage, B; Treil, J; Inglèse, J M; Peyre, A; Kahn, J L; Sixou, M

    2012-01-01

    Objectives The various types of cone beam CT (CBCT) differ in several technical characteristics, notably their spatial resolution, which is defined by the acquisition voxel size. However, data are still lacking on the effects of voxel size on the metric accuracy of three-dimensional (3D) reconstructions. This study was designed to assess the effect of isotropic voxel size on the 3D reconstruction accuracy and reproducibility of CBCT data. Methods The study sample comprised 70 teeth (from the Institut d’Anatomie Normale, Strasbourg, France). The teeth were scanned with a KODAK 9500 3D® CBCT (Carestream Health, Inc., Marne-la-Vallée, France), which has two voxel sizes: 200 µm (CBCT 200 µm group) and 300 µm (CBCT 300 µm group). These teeth had also been scanned with the KODAK 9000 3D® CBCT (Carestream Health, Inc.) (CBCT 76 µm group) and the SCANCO Medical micro-CT XtremeCT (SCANCO Medical, Brüttisellen, Switzerland) (micro-CT 41 µm group) considered as references. After semi-automatic segmentation with AMIRA® software (Visualization Sciences Group, Burlington, MA), tooth volumetric measurements were obtained. Results The Bland–Altman method showed no difference in tooth volumes despite a slight underestimation for the CBCT 200 µm and 300 µm groups compared with the two reference groups. The underestimation was statistically significant for the volumetric measurements of the CBCT 300 µm group relative to the two reference groups (Passing–Bablok method). Conclusions CBCT is not only a tool that helps in diagnosis and detection but it has the complementary advantage of being a measuring instrument, the accuracy of which appears connected to the size of the voxels. Future applications of such measurements with CBCT are discussed. PMID:23166362

  13. Flow effects of blood constitutive equations in 3D models of vascular anomalies

    NASA Astrophysics Data System (ADS)

    Neofytou, Panagiotis; Tsangaris, Sokrates

    2006-06-01

    The effects of different blood rheological models are investigated numerically utilizing two three- dimensional (3D) models of vascular anomalies, namely a stenosis and an abdominal aortic aneurysm model. The employed CFD code incorporates the SIMPLE scheme in conjunction with the finite-volume method with collocated arrangement of variables. The approximation of the convection terms is carried out using the QUICK differencing scheme, whereas the code enables also multi-block computations, which are useful in order to cope with the two-block grid structure of the current computational domain. Three non-Newtonian models are employed, namely the Casson, Power-Law and Quemada models, which have been introduced in the past for modelling the rheological behaviour of blood and cover both the viscous as well as the two-phase character of blood. In view of the haemodynamical mechanisms related to abnormalities in the vascular network and the role of the wall shear stress in initiating and further developing of arterial diseases, the present study focuses on the 3D flow field and in particular on the distribution as well as on both low and high values of the wall shear stress in the vicinity of the anomaly. Finally, a comparison is made between the effects of each rheological model on the aforementioned parameters. Results show marked differences between simulating blood as Newtonian and non-Newtonian fluid and furthermore the Power-Law model exhibits different behaviour in all cases compared to the other models whereas Quemada and Casson models exhibit similar behaviour in the case of the stenosis but different behaviour in the case of the aneurysm.

  14. Regional conductivity structures of the northwestern segment of the North American Plate derived from 3-D inversion of USArray magnetotelluric data

    NASA Astrophysics Data System (ADS)

    Meqbel, N. M.; Egbert, G. D.; Kelbert, A.

    2010-12-01

    Long period (10-20,000 s) magnetotelluric (MT) data are being acquired in a series of temporary arrays deployed across the continental United States through EMScope, a component of EarthScope, a multidisciplinary decade-long project to study the structure and evolution of the North American Continent. MT deployments in 2006-2010 have so far acquired data at 237 sites on an approximately regular grid, with the same nominal spacing as the USArray broadband seismic transportable array (~70 km), covering the Northwestern US, from the Oregon-Washington coast across the Rocky Mountains, into Montana and Wyoming. Preliminary 3-D inversion results (Patro and Egbert; 2008), based on data from the 110 westernmost “Cascadia” sites collected in the first two years, revealed extensive areas of high conductivity in the lower crust beneath the Northwest Basin and Range (NBR), inferred to result from fluids (including possibly partial melt at depth) associated with magmatic underplating, and beneath the Cascade Mountains, probably due to fluids released by the subducting Juan de Fuca slab. Here we extend this study, refining and further testing the preliminary results from Cascadia, and extending the inversion domain to the East, to include all of the EarthScope data. Although site spacing is very broad, distinct regional structures are clearly evident even in simple maps of apparent resistivity, phase and induction vectors. For the 3-D inversion we are using the parallelized version of our recently developed Modular Code (ModEM), which supports Non-Linear Conjugate Gradient and several Gauss-Newton type schemes. Our initial 3-D inversion results using 212 MT sites, fitting impedances and vertical field transfer functions (together and separately) suggest several conductive and resistive structures which appear to be stable and required by the measured data. These include: - A conductive structure elongated in the N-S direction underneath the volcanic arc of the Cascadia

  15. The Effect of Frame Rate on 3D Video Quality and Bitrate

    NASA Astrophysics Data System (ADS)

    Banitalebi-Dehkordi, Amin; Pourazad, Mahsa T.; Nasiopoulos, Panos

    2015-03-01

    Increasing the frame rate of a 3D video generally results in improved Quality of Experience (QoE). However, higher frame rates involve a higher degree of complexity in capturing, transmission, storage, and display. The question that arises here is what frame rate guarantees high viewing quality of experience given the existing/required 3D devices and technologies (3D cameras, 3D TVs, compression, transmission bandwidth, and storage capacity). This question has already been addressed for the case of 2D video, but not for 3D. The objective of this paper is to study the relationship between 3D quality and bitrate at different frame rates. Our performance evaluations show that increasing the frame rate of 3D videos beyond 60 fps may not be visually distinguishable. In addition, our experiments show that when the available bandwidth is reduced, the highest possible 3D quality of experience can be achieved by adjusting (decreasing) the frame rate instead of increasing the compression ratio. The results of our study are of particular interest to network providers for rate adaptation in variable bitrate channels.

  16. 3D-CAD Effects on Creative Design Performance of Different Spatial Abilities Students

    ERIC Educational Resources Information Center

    Chang, Y.

    2014-01-01

    Students' creativity is an important focus globally and is interrelated with students' spatial abilities. Additionally, three-dimensional computer-assisted drawing (3D-CAD) overcomes barriers to spatial expression during the creative design process. Does 3D-CAD affect students' creative abilities? The purpose of this study was to explore the…

  17. 3d-3d correspondence revisited

    DOE PAGES

    Chung, Hee -Joong; Dimofte, Tudor; Gukov, Sergei; ...

    2016-04-21

    In fivebrane compactifications on 3-manifolds, we point out the importance of all flat connections in the proper definition of the effective 3d N = 2 theory. The Lagrangians of some theories with the desired properties can be constructed with the help of homological knot invariants that categorify colored Jones polynomials. Higgsing the full 3d theories constructed this way recovers theories found previously by Dimofte-Gaiotto-Gukov. As a result, we also consider the cutting and gluing of 3-manifolds along smooth boundaries and the role played by all flat connections in this operation.

  18. Effect of 3d doping on the electronic structure of BaFe2As2

    SciTech Connect

    McLeod, John A.; Buling, A.; Green, R.J.; Boyko, T.D.; Skorikov, N.A.; Kurmaev, E.Z.; Neumann, M.; Finkelstein, L.D.; Ni, Ni; Thaler, Alexander; Budko, Serguei L.; Canfield, Paul; Moewes, A.

    2012-04-25

    The electronic structure of BaFe2As2 doped with Co, Ni and Cu has been studied by a variety of experimental and theoretical methods, but a clear picture of the dopant 3d states has not yet emerged. Herein we provide experimental evidence of the distribution of Co, Ni and Cu 3d states in the valence band. We conclude that the Co and Ni 3d states provide additional free carriers to the Fermi level, while the Cu 3d states are found at the bottom of the valence band in a localized 3d10 shell. These findings help shed light on why superconductivity can occur in BaFe2As2 doped with Co and Ni but not Cu.

  19. Terahertz 3D printed diffractive lens matrices for field-effect transistor detector focal plane arrays.

    PubMed

    Szkudlarek, Krzesimir; Sypek, Maciej; Cywiński, Grzegorz; Suszek, Jarosław; Zagrajek, Przemysław; Feduniewicz-Żmuda, Anna; Yahniuk, Ivan; Yatsunenko, Sergey; Nowakowska-Siwińska, Anna; Coquillat, Dominique; But, Dmytro B; Rachoń, Martyna; Węgrzyńska, Karolina; Skierbiszewski, Czesław; Knap, Wojciech

    2016-09-05

    We present the concept, the fabrication processes and the experimental results for materials and optics that can be used for terahertz field-effect transistor detector focal plane arrays. More specifically, we propose 3D printed arrays of a new type - diffractive multi-zone lenses of which the performance is superior to that of previously used mono-zone diffractive or refractive elements and evaluate them with GaN/AlGaN field-effect transistor terahertz detectors. Experiments performed in the 300-GHz atmospheric window show that the lens arrays offer both a good efficiency and good uniformity, and may improve the signal-to-noise ratio of the terahertz field-effect transistor detectors by more than one order of magnitude. In practice, we tested 3 × 12 lens linear arrays with printed circuit board THz detector arrays used in postal security scanners and observed significant signal-to-noise improvements. Our results clearly show that the proposed technology provides a way to produce cost-effective, reproducible, flat optics for large-size field-effect transistor THz-detector focal plane arrays.

  20. The effects of 3D interactive animated graphics on student learning and attitudes in computer-based instruction

    NASA Astrophysics Data System (ADS)

    Moon, Hye Sun

    Visuals are most extensively used as instructional tools in education to present spatially-based information. Recent computer technology allows the generation of 3D animated visuals to extend the presentation in computer-based instruction. Animated visuals in 3D representation not only possess motivational value that promotes positive attitudes toward instruction but also facilitate learning when the subject matter requires dynamic motion and 3D visual cue. In this study, three questions are explored: (1) how 3D graphics affects student learning and attitude, in comparison with 2D graphics; (2) how animated graphics affects student learning and attitude, in comparison with static graphics; and (3) whether the use of 3D graphics, when they are supported by interactive animation, is the most effective visual cues to improve learning and to develop positive attitudes. A total of 145 eighth-grade students participated in a 2 x 2 factorial design study. The subjects were randomly assigned to one of four computer-based instructions: 2D static; 2D animated; 3D static; and 3D animated. The results indicated that: (1) Students in the 3D graphic condition exhibited more positive attitudes toward instruction than those in the 2D graphic condition. No group differences were found between the posttest score of 3D graphic condition and that of 2D graphic condition. However, students in the 3D graphic condition took less time for information retrieval on posttest than those in the 2D graphic condition. (2) Students in the animated graphic condition exhibited slightly more positive attitudes toward instruction than those in the static graphic condition. No group differences were found between the posttest score of animated graphic condition and that of static graphic condition. However, students in the animated graphic condition took less time for information retrieval on posttest than those in the static graphic condition. (3) Students in the 3D animated graphic condition

  1. 3D finite element simulation of effects of deflection rate on energy absorption for TRIP steel

    NASA Astrophysics Data System (ADS)

    Hayashi, Asuka; Pham, Hang; Iwamoto, Takeshi

    2015-09-01

    Recently, with the requirement of lighter weight and more safety for a design of automobile, energy absorption capability of structural materials has become important. TRIP (Transformation-induced Plasticity) steel is expected to apply to safety members because of excellent energy absorption capability and ductility. Past studies proved that such excellent characteristics in TRIP steel are dominated by strain-induced martensitic transformation (SIMT) during plastic deformation. Because SIMT strongly depends on deformation rate and temperature, an investigation of the effects of deformation rate and temperature on energy absorption in TRIP is essential. Although energy absorption capability of material can be estimated by J-integral experimentally by using pre-cracked specimen, it is difficult to determine volume fraction of martensite and temperature rise during the crack extension. In addition, their effects on J-integral, especially at high deformation rate in experiment might be quite hard. Thus, a computational prediction needs to be performed. In this study, bending deformation behavior of pre-cracked specimen until the onset point of crack extension are predicted by 3D finite element simulation based on the transformation kinetics model proposed by Iwamoto et al. (1998). It is challenged to take effects of temperature, volume fraction of martensite and deformation rate into account. Then, the mechanism for higher energy absorption characteristic will be discussed.

  2. Radiation Quality Effects on Transcriptome Profiles in 3-d Cultures After Particle Irradiation

    NASA Technical Reports Server (NTRS)

    Patel, Z. S.; Kidane, Y. H.; Huff, J. L.

    2014-01-01

    In this work, we evaluate the differential effects of low- and high-LET radiation on 3-D organotypic cultures in order to investigate radiation quality impacts on gene expression and cellular responses. Reducing uncertainties in current risk models requires new knowledge on the fundamental differences in biological responses (the so-called radiation quality effects) triggered by heavy ion particle radiation versus low-LET radiation associated with Earth-based exposures. We are utilizing novel 3-D organotypic human tissue models that provide a format for study of human cells within a realistic tissue framework, thereby bridging the gap between 2-D monolayer culture and animal models for risk extrapolation to humans. To identify biological pathway signatures unique to heavy ion particle exposure, functional gene set enrichment analysis (GSEA) was used with whole transcriptome profiling. GSEA has been used extensively as a method to garner biological information in a variety of model systems but has not been commonly used to analyze radiation effects. It is a powerful approach for assessing the functional significance of radiation quality-dependent changes from datasets where the changes are subtle but broad, and where single gene based analysis using rankings of fold-change may not reveal important biological information. We identified 45 statistically significant gene sets at 0.05 q-value cutoff, including 14 gene sets common to gamma and titanium irradiation, 19 gene sets specific to gamma irradiation, and 12 titanium-specific gene sets. Common gene sets largely align with DNA damage, cell cycle, early immune response, and inflammatory cytokine pathway activation. The top gene set enriched for the gamma- and titanium-irradiated samples involved KRAS pathway activation and genes activated in TNF-treated cells, respectively. Another difference noted for the high-LET samples was an apparent enrichment in gene sets involved in cycle cycle/mitotic control. It is

  3. SU-E-J-55: End-To-End Effectiveness Analysis of 3D Surface Image Guided Voluntary Breath-Holding Radiotherapy for Left Breast

    SciTech Connect

    Lin, M; Feigenberg, S

    2015-06-15

    Purpose To evaluate the effectiveness of using 3D-surface-image to guide breath-holding (BH) left-side breast treatment. Methods Two 3D surface image guided BH procedures were implemented and evaluated: normal-BH, taking BH at a comfortable level, and deep-inspiration-breath-holding (DIBH). A total of 20 patients (10 Normal-BH and 10 DIBH) were recruited. Patients received a BH evaluation using a commercialized 3D-surface- tracking-system (VisionRT, London, UK) to quantify the reproducibility of BH positions prior to CT scan. Tangential 3D/IMRT plans were conducted. Patients were initially setup under free-breathing (FB) condition using the FB surface obtained from the untaged CT to ensure a correct patient position. Patients were then guided to reach the planned BH position using the BH surface obtained from the BH CT. Action-levels were set at each phase of treatment process based on the information provided by the 3D-surface-tracking-system for proper interventions (eliminate/re-setup/ re-coaching). We reviewed the frequency of interventions to evaluate its effectiveness. The FB-CBCT and port-film were utilized to evaluate the accuracy of 3D-surface-guided setups. Results 25% of BH candidates with BH positioning uncertainty > 2mm are eliminated prior to CT scan. For >90% of fractions, based on the setup deltas from3D-surface-trackingsystem, adjustments of patient setup are needed after the initial-setup using laser. 3D-surface-guided-setup accuracy is comparable as CBCT. For the BH guidance, frequency of interventions (a re-coaching/re-setup) is 40%(Normal-BH)/91%(DIBH) of treatments for the first 5-fractions and then drops to 16%(Normal-BH)/46%(DIBH). The necessity of re-setup is highly patient-specific for Normal-BH but highly random among patients for DIBH. Overall, a −0.8±2.4 mm accuracy of the anterior pericardial shadow position was achieved. Conclusion 3D-surface-image technology provides effective intervention to the treatment process and ensures

  4. The effects of task difficulty on visual search strategy in virtual 3D displays

    PubMed Central

    Pomplun, Marc; Garaas, Tyler W.; Carrasco, Marisa

    2013-01-01

    Analyzing the factors that determine our choice of visual search strategy may shed light on visual behavior in everyday situations. Previous results suggest that increasing task difficulty leads to more systematic search paths. Here we analyze observers' eye movements in an “easy” conjunction search task and a “difficult” shape search task to study visual search strategies in stereoscopic search displays with virtual depth induced by binocular disparity. Standard eye-movement variables, such as fixation duration and initial saccade latency, as well as new measures proposed here, such as saccadic step size, relative saccadic selectivity, and x−y target distance, revealed systematic effects on search dynamics in the horizontal-vertical plane throughout the search process. We found that in the “easy” task, observers start with the processing of display items in the display center immediately after stimulus onset and subsequently move their gaze outwards, guided by extrafoveally perceived stimulus color. In contrast, the “difficult” task induced an initial gaze shift to the upper-left display corner, followed by a systematic left-right and top-down search process. The only consistent depth effect was a trend of initial saccades in the easy task with smallest displays to the items closest to the observer. The results demonstrate the utility of eye-movement analysis for understanding search strategies and provide a first step toward studying search strategies in actual 3D scenarios. PMID:23986539

  5. Convection and chemistry effects in CVD: A 3-D analysis for silicon deposition

    NASA Technical Reports Server (NTRS)

    Gokoglu, S. A.; Kuczmarski, M. A.; Tsui, P.; Chait, A.

    1989-01-01

    The computational fluid dynamics code FLUENT has been adopted to simulate the entire rectangular-channel-like (3-D) geometry of an experimental CVD reactor designed for Si deposition. The code incorporated the effects of both homogeneous (gas phase) and heterogeneous (surface) chemistry with finite reaction rates of important species existing in silane dissociation. The experiments were designed to elucidate the effects of gravitationally-induced buoyancy-driven convection flows on the quality of the grown Si films. This goal is accomplished by contrasting the results obtained from a carrier gas mixture of H2/Ar with the ones obtained from the same molar mixture ratio of H2/He, without any accompanying change in the chemistry. Computationally, these cases are simulated in the terrestrial gravitational field and in the absence of gravity. The numerical results compare favorably with experiments. Powerful computational tools provide invaluable insights into the complex physicochemical phenomena taking place in CVD reactors. Such information is essential for the improved design and optimization of future CVD reactors.

  6. An Examination of the Effects of Collaborative Scientific Visualization via Model-based Reasoning on Science, Technology, Engineering, and Mathematics (STEM) Learning Within an Immersive 3D World

    NASA Astrophysics Data System (ADS)

    Soleimani, Ali

    Immersive 3D worlds can be designed to effectively engage students in peer-to-peer collaborative learning activities, supported by scientific visualization, to help with understanding complex concepts associated with learning science, technology, engineering, and mathematics (STEM). Previous research studies have shown STEM learning benefits associated with the use of scientific visualization tools involving model-based reasoning (MBR). Little is known, however, about collaborative use of scientific visualization, via MBR, within an immersive 3D-world learning environment for helping to improve perceived value of STEM learning and knowledge acquisition in a targeted domain such as geothermal energy. Geothermal energy was selected as the study's STEM focus, because understanding in the domain is highly dependent on successfully integrating science and mathematics concepts. This study used a 2x2 Mixed ANOVA, with repeated measures, design to analyze collaborative usage of a geothermal energy MBR model and its effects on learning within an immersive 3D world. The immersive 3D world used for the study is supported by the Open Simulator platform. Findings from this study can suggest ways to improve STEM learning and inform the design of MBR activities when conducted within an immersive 3D world.

  7. Impact of 3-D printed PLA- and chitosan-based scaffolds on human monocyte/macrophage responses: unraveling the effect of 3-D structures on inflammation.

    PubMed

    Almeida, Catarina R; Serra, Tiziano; Oliveira, Marta I; Planell, Josep A; Barbosa, Mário A; Navarro, Melba

    2014-02-01

    Recent studies have pointed towards a decisive role of inflammation in triggering tissue repair and regeneration, while at the same time it is accepted that an exacerbated inflammatory response may lead to rejection of an implant. Within this context, understanding and having the capacity to regulate the inflammatory response elicited by 3-D scaffolds aimed for tissue regeneration is crucial. This work reports on the analysis of the cytokine profile of human monocytes/macrophages in contact with biodegradable 3-D scaffolds with different surface properties, architecture and controlled pore geometry, fabricated by 3-D printing technology. Fabrication processes were optimized to create four different 3-D platforms based on polylactic acid (PLA), PLA/calcium phosphate glass or chitosan. Cytokine secretion and cell morphology of human peripheral blood monocytes allowed to differentiate on the different matrices were analyzed. While all scaffolds supported monocyte/macrophage adhesion and stimulated cytokine production, striking differences between PLA-based and chitosan scaffolds were found, with chitosan eliciting increased secretion of tumor necrosis factor (TNF)-α, while PLA-based scaffolds induced higher production of interleukin (IL)-6, IL-12/23 and IL-10. Even though the material itself induced the biggest differences, the scaffold geometry also impacted on TNF-α and IL-12/23 production, with chitosan scaffolds having larger pores and wider angles leading to a higher secretion of these pro-inflammatory cytokines. These findings strengthen the appropriateness of these 3-D platforms to study modulation of macrophage responses by specific parameters (chemistry, topography, scaffold architecture).

  8. Kinematic ground motion simulations on rough faults including effects of 3D stochastic velocity perturbations

    USGS Publications Warehouse

    Graves, Robert; Pitarka, Arben

    2016-01-01

    We describe a methodology for generating kinematic earthquake ruptures for use in 3D ground‐motion simulations over the 0–5 Hz frequency band. Our approach begins by specifying a spatially random slip distribution that has a roughly wavenumber‐squared fall‐off. Given a hypocenter, the rupture speed is specified to average about 75%–80% of the local shear wavespeed and the prescribed slip‐rate function has a Kostrov‐like shape with a fault‐averaged rise time that scales self‐similarly with the seismic moment. Both the rupture time and rise time include significant local perturbations across the fault surface specified by spatially random fields that are partially correlated with the underlying slip distribution. We represent velocity‐strengthening fault zones in the shallow (<5  km) and deep (>15  km) crust by decreasing rupture speed and increasing rise time in these regions. Additional refinements to this approach include the incorporation of geometric perturbations to the fault surface, 3D stochastic correlated perturbations to the P‐ and S‐wave velocity structure, and a damage zone surrounding the shallow fault surface characterized by a 30% reduction in seismic velocity. We demonstrate the approach using a suite of simulations for a hypothetical Mw 6.45 strike‐slip earthquake embedded in a generalized hard‐rock velocity structure. The simulation results are compared with the median predictions from the 2014 Next Generation Attenuation‐West2 Project ground‐motion prediction equations and show very good agreement over the frequency band 0.1–5 Hz for distances out to 25 km from the fault. Additionally, the newly added features act to reduce the coherency of the radiated higher frequency (f>1  Hz) ground motions, and homogenize radiation‐pattern effects in this same bandwidth, which move the simulations closer to the statistical characteristics of observed motions as illustrated by comparison with recordings from

  9. On the effect of muscular cocontraction on the 3-D human arm impedance.

    PubMed

    Patel, Harshil; O'Neill, Gerald; Artemiadis, Panagiotis

    2014-10-01

    Humans have the inherent ability to perform highly dexterous tasks with their arms, involving maintenance of posture, movement, and interaction with the environment. The latter requires the human to control the dynamic characteristics of the upper limb musculoskeletal system. These characteristics are quantitatively represented by inertia, damping, and stiffness, which are measures of mechanical impedance. Many previous studies have shown that arm posture is a dominant factor in determining the end point impedance on a horizontal plane. This paper presents the characterization of the end point impedance of the human arm in 3-D space. Moreover, it models the regulation of the arm impedance with muscle cocontraction. The characterization is made by route of experimental trials where human subjects maintained arm posture while their arms were perturbed by a robot arm. Furthermore, the subjects were asked to control the level of their arm muscles' cocontraction, using visual feedback, in order to investigate the effect of muscle cocontraction on the arm impedance. The results of this study show an anisotropic increase of arm stiffness due to muscle cocontraction. These results could improve our understanding of the human arm biomechanics, as well as provide implications for human motor control-specifically the control of arm impedance through muscle cocontraction.

  10. Permuting input for more effective sampling of 3D conformer space

    NASA Astrophysics Data System (ADS)

    Carta, Giorgio; Onnis, Valeria; Knox, Andrew J. S.; Fayne, Darren; Lloyd, David G.

    2006-03-01

    SMILES strings and other classic 2D structural formats offer a convenient way to represent molecules as a simplistic connection table, with the inherent advantages of ease of handling and storage. In the context of virtual screening, chemical databases to be screened are often initially represented by canonicalised SMILES strings that can be filtered and pre-processed in a number of ways, resulting in molecules that occupy similar regions of chemical space to active compounds of a therapeutic target. A wide variety of software exists to convert molecules into SMILES format, namely, Mol2smi (Daylight Inc.), MOE (Chemical Computing Group) and Babel (Openeye Scientific Software). Depending on the algorithm employed, the atoms of a SMILES string defining a molecule can be ordered differently. Upon conversion to 3D coordinates they result in the production of ostensibly the same molecule. In this work we show how different permutations of a SMILES string can affect conformer generation, affecting reliability and repeatability of the results. Furthermore, we propose a novel procedure for the generation of conformers, taking advantage of the permutation of the input strings—both SMILES and other 2D formats, leading to more effective sampling of conformation space in output, and also implementing fingerprint and principal component analyses step to post process and visualise the results.

  11. CAST: Effective and Efficient User Interaction for Context-Aware Selection in 3D Particle Clouds.

    PubMed

    Yu, Lingyun; Efstathiou, Konstantinos; Isenberg, Petra; Isenberg, Tobias

    2016-01-01

    We present a family of three interactive Context-Aware Selection Techniques (CAST) for the analysis of large 3D particle datasets. For these datasets, spatial selection is an essential prerequisite to many other analysis tasks. Traditionally, such interactive target selection has been particularly challenging when the data subsets of interest were implicitly defined in the form of complicated structures of thousands of particles. Our new techniques SpaceCast, TraceCast, and PointCast improve usability and speed of spatial selection in point clouds through novel context-aware algorithms. They are able to infer a user's subtle selection intention from gestural input, can deal with complex situations such as partially occluded point clusters or multiple cluster layers, and can all be fine-tuned after the selection interaction has been completed. Together, they provide an effective and efficient tool set for the fast exploratory analysis of large datasets. In addition to presenting Cast, we report on a formal user study that compares our new techniques not only to each other but also to existing state-of-the-art selection methods. Our results show that Cast family members are virtually always faster than existing methods without tradeoffs in accuracy. In addition, qualitative feedback shows that PointCast and TraceCast were strongly favored by our participants for intuitiveness and efficiency.

  12. On Integral Invariants for Effective 3-D Motion Trajectory Matching and Recognition.

    PubMed

    Shao, Zhanpeng; Li, Youfu

    2016-02-01

    Motion trajectories tracked from the motions of human, robots, and moving objects can provide an important clue for motion analysis, classification, and recognition. This paper defines some new integral invariants for a 3-D motion trajectory. Based on two typical kernel functions, we design two integral invariants, the distance and area integral invariants. The area integral invariants are estimated based on the blurred segment of noisy discrete curve to avoid the computation of high-order derivatives. Such integral invariants for a motion trajectory enjoy some desirable properties, such as computational locality, uniqueness of representation, and noise insensitivity. Moreover, our formulation allows the analysis of motion trajectories at a range of scales by varying the scale of kernel function. The features of motion trajectories can thus be perceived at multiscale levels in a coarse-to-fine manner. Finally, we define a distance function to measure the trajectory similarity to find similar trajectories. Through the experiments, we examine the robustness and effectiveness of the proposed integral invariants and find that they can capture the motion cues in trajectory matching and sign recognition satisfactorily.

  13. An Effective 3D Shape Descriptor for Object Recognition with RGB-D Sensors

    PubMed Central

    Liu, Zhong; Zhao, Changchen; Wu, Xingming; Chen, Weihai

    2017-01-01

    RGB-D sensors have been widely used in various areas of computer vision and graphics. A good descriptor will effectively improve the performance of operation. This article further analyzes the recognition performance of shape features extracted from multi-modality source data using RGB-D sensors. A hybrid shape descriptor is proposed as a representation of objects for recognition. We first extracted five 2D shape features from contour-based images and five 3D shape features over point cloud data to capture the global and local shape characteristics of an object. The recognition performance was tested for category recognition and instance recognition. Experimental results show that the proposed shape descriptor outperforms several common global-to-global shape descriptors and is comparable to some partial-to-global shape descriptors that achieved the best accuracies in category and instance recognition. Contribution of partial features and computational complexity were also analyzed. The results indicate that the proposed shape features are strong cues for object recognition and can be combined with other features to boost accuracy. PMID:28245553

  14. Local and Global 3-D Effects in the Magnetic Reconnection Experiment (MRX)

    NASA Astrophysics Data System (ADS)

    Dorfman, S.; Ji, H.; Yamada, M.; Oz, E.; Yoo, J.; Daughton, W.; Roytershteyn, V.

    2009-11-01

    One of the key open questions in Magnetic Reconnection is the nature of the mechanism that governs the reconnection rate in real astrophysical and laboratory systems. Comparisons between fully kinetic 2-D simulations of the Magnetic Reconnection Experiment (MRX) and experimental data show that the 2-D, collisionless expression for the electric field due to particle dynamics [1] does not match MRX data; related to this is a factor of 3-5 discrepancy in the layer width [2,3]. Adding collisions to the simulation leads to a broadening of the layer, but the level of collisionality present in MRX may not be high enough to resolve the discrepancy. Ongoing research on MRX explores the role of fluctuations and 3-D effects in the force balance. Significant toroidal asymmetries have been found, manifested by regions of high inductive electric field moving in the electron flow direction within the layer. Electromagnetic fluctuations in the lower hybrid frequency range [4] tend to occur in discharges with high local currents and a rapid local reconnection rate. The precise relation of these phenomena to fast reconnection is actively being investigated. [1] M. Hesse, et al., Phys. Plasmas, 6:1781 (1999). [2] Y. Ren, et al., Phys. Plasmas 15, 082113 (2008). [3] S. Dorfman, et al., Phys. Plasmas 15, 102107 (2008). [4] H. Ji, et al., Phys.Rev.Lett. 92 (2004) 115001. Supported by NDSEG, DOE, NASA, and NSF.

  15. Numerical study of the 3-D effect on FEL performance and its application to the APS LEUTL FEL

    SciTech Connect

    Chae, Y.C.

    1998-09-01

    A Low-Energy Undulator Test Line (LEUTL) is under construction at the Advanced Photon Source (APS). In LEUTL periodic focusing is provided by external quadrupoles. This results in an elliptical beam with its betatron oscillation envelope varying along the undulators. The free-electron laser (FEL) interaction with such a beam will exhibit truly 3-D effects. Thus the investigation of 3-D effects is important in optimizing the FEL performance. The programs GINGER and TDA3D, coupled with theoretically known facts, have been used for this purpose. Both programs are fully 3-D in moving the particle, but model the interaction between particles and axially symmetric electromagnetic waves. Even though TDA3D can include a few azimuthal modes in the interaction, it is still not a fully 3-D FEL code. However, they show that these 2-D programs can still be used for an elliptical beam whose aspect ratio is within certain limits. The author presents numerical results of FEL performance for the circular beam, the elliptical beam, and finally for the beam in the realistic LEUTL lattice.

  16. AE3D

    SciTech Connect

    Spong, Donald A

    2016-06-20

    AE3D solves for the shear Alfven eigenmodes and eigenfrequencies in a torodal magnetic fusion confinement device. The configuration can be either 2D (e.g. tokamak, reversed field pinch) or 3D (e.g. stellarator, helical reversed field pinch, tokamak with ripple). The equations solved are based on a reduced MHD model and sound wave coupling effects are not currently included.

  17. Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance

    PubMed Central

    Varghese, Anitha; Yee, Michael S; Chan, Cheuk F; Crowe, Lindsey A; Keenan, Niall G; Johnston, Desmond G; Pennell, Dudley J

    2009-01-01

    Background There is recent evidence suggesting that rosiglitazone increases death from cardiovascular causes. We investigated the direct effect of this drug on atheroma using 3D carotid cardiovascular magnetic resonance. Results A randomized, placebo-controlled, double-blind study was performed to evaluate the effect of rosiglitazone treatment on carotid atherosclerosis in subjects with type 2 diabetes and coexisting vascular disease or hypertension. The primary endpoint of the study was the change from baseline to 52 weeks of carotid arterial wall volume, reflecting plaque burden, as measured by carotid cardiovascular magnetic resonance. Rosiglitazone or placebo was allocated to 28 and 29 patients respectively. Patients were managed to have equivalent glycemic control over the study period, but in fact the rosiglitazone group lowered their HbA1c by 0.88% relative to placebo (P < 0.001). Most patients received a statin or fibrate as lipid control medication (rosiglitazone 78%, controls 83%). Data are presented as mean ± SD. At baseline, the carotid arterial wall volume in the placebo group was 1146 ± 550 mm3 and in the rosiglitazone group was 1354 ± 532 mm3. After 52 weeks, the respective volumes were 1134 ± 523 mm3 and 1348 ± 531 mm3. These changes (-12.1 mm3 and -5.7 mm3 in the placebo and rosiglitazone groups, respectively) were not statistically significant between groups (P = 0.57). Conclusion Treatment with rosiglitazone over 1 year had no effect on progression of carotid atheroma in patients with type 2 diabetes mellitus compared to placebo. PMID:19635160

  18. Numerical Simulation of the Effect of 3D Needle Movement on Cavitation and Spray Formation in a Diesel Injector

    NASA Astrophysics Data System (ADS)

    Mandumpala Devassy, B.; Edelbauer, W.; Greif, D.

    2015-12-01

    Cavitation and its effect on spray formation and its dispersion play a crucial role in proper engine combustion and controlled emission. This study focuses on these effects in a typical common rail 6-hole diesel injector accounting for 3D needle movement and flow compressibility effects. Coupled numerical simulations using 1D and 3D CFD codes are used for this investigation. Previous studies in this direction have already presented a detailed structure of the adopted methodology. Compared to the previous analysis, the present study investigates the effect of 3D needle movement and cavitation on the spray formation for pilot and main injection events for a typical diesel engine operating point. The present setup performs a 3D compressible multiphase simulation coupled with a standalone 1D high pressure flow simulation. The simulation proceeds by the mutual communication between 1D and 3D solvers. In this work a typical common rail injector with a mini-sac nozzle is studied. The lateral and radial movement of the needle and its effect on the cavitation generation and the subsequent spray penetration are analyzed. The result indicates the effect of compressibility of the liquid on damping the needle forces, and also the difference in the spray penetration levels due to the asymmetrical flow field. Therefore, this work intends to provide an efficient and user-friendly engineering tool for simulating a complete fuel injector including spray propagation.

  19. Zebrafish response to 3D printed shoals of conspecifics: the effect of body size.

    PubMed

    Bartolini, Tiziana; Mwaffo, Violet; Showler, Ashleigh; Macrì, Simone; Butail, Sachit; Porfiri, Maurizio

    2016-02-18

    Recent progress in three-dimensional (3D) printing technology has enabled rapid prototyping of complex models at a limited cost. Virtually every research laboratory has access to a 3D printer, which can assist in the design and implementation of hypothesis-driven studies on animal behavior. In this study, we explore the possibility of using 3D printing technology to understand the role of body size in the social behavior of the zebrafish model organism. In a dichotomous preference test, we study the behavioral response of zebrafish to shoals of 3D printed replicas of varying size. We systematically vary the size of each replica without altering the coloration, aspect ratio, and stripe patterns, which are all selected to closely mimic zebrafish morphophysiology. The replicas are actuated through a robotic manipulator, mimicking the natural motion of live subjects. Zebrafish preference is assessed by scoring the time spent in the vicinity of the shoal of replicas, and the information theoretic construct of transfer entropy is used to further elucidate the influence of the replicas on zebrafish motion. Our results demonstrate that zebrafish adjust their behavior in response to variations in the size of the replicas. Subjects exhibit an avoidance reaction for larger replicas, and they are attracted toward and influenced by smaller replicas. The approach presented in this study, integrating 3D printing technology, robotics, and information theory, is expected to significantly aid preclinical research on zebrafish behavior.

  20. In vivo 3D analysis of systemic effects after local heavy-ion beam irradiation in an animal model.

    PubMed

    Nagata, Kento; Hashimoto, Chika; Watanabe-Asaka, Tomomi; Itoh, Kazusa; Yasuda, Takako; Ohta, Kousaku; Oonishi, Hisako; Igarashi, Kento; Suzuki, Michiyo; Funayama, Tomoo; Kobayashi, Yasuhiko; Nishimaki, Toshiyuki; Katsumura, Takafumi; Oota, Hiroki; Ogawa, Motoyuki; Oga, Atsunori; Ikemoto, Kenzo; Itoh, Hiroshi; Kutsuna, Natsumaro; Oda, Shoji; Mitani, Hiroshi

    2016-06-27

    Radiotherapy is widely used in cancer treatment. In addition to inducing effects in the irradiated area, irradiation may induce effects on tissues close to and distant from the irradiated area. Japanese medaka, Oryzias latipes, is a small teleost fish and a model organism for evaluating the environmental effects of radiation. In this study, we applied low-energy carbon-ion (26.7 MeV/u) irradiation to adult medaka to a depth of approximately 2.2 mm from the body surface using an irradiation system at the National Institutes for Quantum and Radiological Science and Technology. We histologically evaluated the systemic alterations induced by irradiation using serial sections of the whole body, and conducted a heart rate analysis. Tissues from the irradiated side showed signs of serious injury that corresponded with the radiation dose. A 3D reconstruction analysis of the kidney sections showed reductions in the kidney volume and blood cell mass along the irradiated area, reflecting the precise localization of the injuries caused by carbon-beam irradiation. Capillary aneurysms were observed in the gill in both ventrally and dorsally irradiated fish, suggesting systemic irradiation effects. The present study provides an in vivo model for further investigation of the effects of irradiation beyond the locally irradiated area.

  1. In vivo 3D analysis of systemic effects after local heavy-ion beam irradiation in an animal model

    PubMed Central

    Nagata, Kento; Hashimoto, Chika; Watanabe-Asaka, Tomomi; Itoh, Kazusa; Yasuda, Takako; Ohta, Kousaku; Oonishi, Hisako; Igarashi, Kento; Suzuki, Michiyo; Funayama, Tomoo; Kobayashi, Yasuhiko; Nishimaki, Toshiyuki; Katsumura, Takafumi; Oota, Hiroki; Ogawa, Motoyuki; Oga, Atsunori; Ikemoto, Kenzo; Itoh, Hiroshi; Kutsuna, Natsumaro; Oda, Shoji; Mitani, Hiroshi

    2016-01-01

    Radiotherapy is widely used in cancer treatment. In addition to inducing effects in the irradiated area, irradiation may induce effects on tissues close to and distant from the irradiated area. Japanese medaka, Oryzias latipes, is a small teleost fish and a model organism for evaluating the environmental effects of radiation. In this study, we applied low-energy carbon-ion (26.7 MeV/u) irradiation to adult medaka to a depth of approximately 2.2 mm from the body surface using an irradiation system at the National Institutes for Quantum and Radiological Science and Technology. We histologically evaluated the systemic alterations induced by irradiation using serial sections of the whole body, and conducted a heart rate analysis. Tissues from the irradiated side showed signs of serious injury that corresponded with the radiation dose. A 3D reconstruction analysis of the kidney sections showed reductions in the kidney volume and blood cell mass along the irradiated area, reflecting the precise localization of the injuries caused by carbon-beam irradiation. Capillary aneurysms were observed in the gill in both ventrally and dorsally irradiated fish, suggesting systemic irradiation effects. The present study provides an in vivo model for further investigation of the effects of irradiation beyond the locally irradiated area. PMID:27345436

  2. 3-D numerical simulations of eruption clouds: Effects of the environmental wind on the turbulent mixing

    NASA Astrophysics Data System (ADS)

    Suzuki, Y. J.; Koyaguchi, T.

    2011-12-01

    During an explosive volcanic eruption, a mixture of volcanic gas and solid pyroclasts are ejected from a volcanic vent with a high temperature. As it rises, the mixture entrains ambient air owing to turbulent mixing. The entrained air expands by heating from the hot pyroclasts, and the eruption cloud (i.e., the ejected material plus the entrained air) rises as a buoyant plume. Because the plume height is principally determined by the balance between the thermal energy ejected at the vent and the work done in transporting the ejected material plus entrained air through the atmospheric stratification, it is controlled by the efficiency of turbulent mixing; as the amount of entrained air increases, the plume height decreases. In the 1-D models of eruption column (e.g., Woods, 1988), the plume height is calculated on the assumption that the mean inflow velocity across the edge of turbulent jet and/or plume is proportional to the mean vertical velocity (Morton et al., 1956). Experimental studies suggest that the proportionality constant (i.e., entrainment coefficient, k), which represents the efficiency of turbulent mixing, is about 0.10 for pure plumes when there is no wind. When an environmental wind is present, however, the interaction between a buoyant plume and the wind may enhance the entrainment of air and can significantly decrease the plume height (Bursik, 2001). In order to investigate the effects of wind on the vortical structures and the efficiency of turbulent mixing in an eruption cloud, we have carried out 3-D numerical simulations of eruption column which is ejected in a wind field. The simulation results indicate that a buoyant plume vertically rises as a "strong plume" (e.g., Bonadonna et al., 2003) when the wind velocity is low: the cloud reaches the neutral buoyancy level and overshoots until the upward momentum is exhausted. In this case, the plume height is consistent with prediction by the 1-D model with k~0.10. When the wind velocity is high, on

  3. Use of reconstructed 3D VMEC equilibria to match effects of toroidally rotating discharges in DIII-D

    SciTech Connect

    Wingen, Andreas; Wilcox, Robert S.; Cianciosa, Mark R.; Seal, Sudip K.; Unterberg, Ezekial A.; Hanson, Jeremy M.; Hirshman, Steven Paul; Lao, L. L.; Logan, N. C.; Paz-Soldan, Carlos; Shafer, Morgan W.

    2016-10-13

    Here, a technique for tokamak equilibrium reconstructions is used for multiple DIII-D discharges, including L-mode and H-mode cases when weakly 3D fields $\\left(\\delta B/B\\sim {{10}^{-3}}\\right)$ are applied. The technique couples diagnostics to the non-linear, ideal MHD equilibrium solver VMEC, using the V3FIT code, to find the most likely 3D equilibrium based on a suite of measurements. It is demonstrated that V3FIT can be used to find non-linear 3D equilibria that are consistent with experimental measurements of the plasma response to very weak 3D perturbations, as well as with 2D profile measurements. Observations at DIII-D show that plasma rotation larger than 20 krad s–1 changes the relative phase between the applied 3D fields and the measured plasma response. Discharges with low averaged rotation (10 krad s–1) and peaked rotation profiles (40 krad s–1) are reconstructed. Similarities and differences to forward modeled VMEC equilibria, which do not include rotational effects, are shown. Toroidal phase shifts of up to ${{30}^{\\circ}}$ are found between the measured and forward modeled plasma responses at the highest values of rotation. The plasma response phases of reconstructed equilibra on the other hand match the measured ones. This is the first time V3FIT has been used to reconstruct weakly 3D tokamak equilibria.

  4. Use of reconstructed 3D VMEC equilibria to match effects of toroidally rotating discharges in DIII-D

    NASA Astrophysics Data System (ADS)

    Wingen, A.; Wilcox, R. S.; Cianciosa, M. R.; Seal, S. K.; Unterberg, E. A.; Hanson, J. M.; Hirshman, S. P.; Lao, L. L.; Logan, N. C.; Paz-Soldan, C.; Shafer, M. W.

    2017-01-01

    A technique for tokamak equilibrium reconstructions is used for multiple DIII-D discharges, including L-mode and H-mode cases when weakly 3D fields ≤ft(δ B/B˜ {{10}-3}\\right) are applied. The technique couples diagnostics to the non-linear, ideal MHD equilibrium solver VMEC, using the V3FIT code, to find the most likely 3D equilibrium based on a suite of measurements. It is demonstrated that V3FIT can be used to find non-linear 3D equilibria that are consistent with experimental measurements of the plasma response to very weak 3D perturbations, as well as with 2D profile measurements. Observations at DIII-D show that plasma rotation larger than 20 krad s-1 changes the relative phase between the applied 3D fields and the measured plasma response. Discharges with low averaged rotation (10 krad s-1) and peaked rotation profiles (40 krad s-1) are reconstructed. Similarities and differences to forward modeled VMEC equilibria, which do not include rotational effects, are shown. Toroidal phase shifts of up to {{30}\\circ} are found between the measured and forward modeled plasma responses at the highest values of rotation. The plasma response phases of reconstructed equilibra on the other hand match the measured ones. This is the first time V3FIT has been used to reconstruct weakly 3D tokamak equilibria.

  5. Effects of 3D microlens transfer into fused silica substrate by CF4/O2 dry etching

    NASA Astrophysics Data System (ADS)

    Grigaliūnas, Viktoras; Jucius, Dalius; Lazauskas, Algirdas; Andrulevičius, Mindaugas; Sakaliūnienė, Jolita; Abakevičienė, Brigita; Kopustinskas, Vitoldas; Smetona, Saulius; Tamulevičius, Sigitas

    2017-01-01

    Nowadays, 3D microoptical elements find a variety of applications from light emitting diodes and household appliances to precise medical endoscopes. Such elements, fabricated in a fused silica substrate by combining 3D e-beam patterning and dry etching, can be used as a mold for the high throughput replication in polymeric materials by UV nanoimprint technique. Flexible and precise control of 3D shape in the resist layer can be achieved by e-beam patterning, but it is also very important to know peculiarities of 3D pattern transfer from resist layer into the fused silica substrate. This paper reports on the effects of PMMA 3D microlens pattern transfer into fused silica substrate by CF4/O2 dry etching. It is demonstrated that etching rate ratio between PMMA and fused silica changes during plasma treatment. Thus, the resulting shape of transferred 3D profile is different from the shape in PMMA and this variation must be assessed during the design phase.

  6. Use of reconstructed 3D VMEC equilibria to match effects of toroidally rotating discharges in DIII-D

    DOE PAGES

    Wingen, Andreas; Wilcox, Robert S.; Cianciosa, Mark R.; ...

    2016-10-13

    Here, a technique for tokamak equilibrium reconstructions is used for multiple DIII-D discharges, including L-mode and H-mode cases when weakly 3D fieldsmore » $$\\left(\\delta B/B\\sim {{10}^{-3}}\\right)$$ are applied. The technique couples diagnostics to the non-linear, ideal MHD equilibrium solver VMEC, using the V3FIT code, to find the most likely 3D equilibrium based on a suite of measurements. It is demonstrated that V3FIT can be used to find non-linear 3D equilibria that are consistent with experimental measurements of the plasma response to very weak 3D perturbations, as well as with 2D profile measurements. Observations at DIII-D show that plasma rotation larger than 20 krad s–1 changes the relative phase between the applied 3D fields and the measured plasma response. Discharges with low averaged rotation (10 krad s–1) and peaked rotation profiles (40 krad s–1) are reconstructed. Similarities and differences to forward modeled VMEC equilibria, which do not include rotational effects, are shown. Toroidal phase shifts of up to $${{30}^{\\circ}}$$ are found between the measured and forward modeled plasma responses at the highest values of rotation. The plasma response phases of reconstructed equilibra on the other hand match the measured ones. This is the first time V3FIT has been used to reconstruct weakly 3D tokamak equilibria.« less

  7. Effects of Processing and Medical Sterilization Techniques on 3D-Printed and Molded Polylactic Acid

    NASA Astrophysics Data System (ADS)

    Geritano, Mariah Nicole

    Manufacturing industries have evolved tremendously in the past decade with the introduction of Additive Manufacturing (AM), also known as 3D Printing. The medical device industry has been a leader in adapting this new technology into research and development. 3D printing enables medical devices and implants to become more customizable, patient specific, and allows for low production numbers. This study compares the mechanical and thermal properties of traditionally manufactured parts versus parts manufactured through 3D printing before and after sterilization, and the ability of an FDM printer to produce reliable, identical samples. It was found that molded samples and 100% infill high-resolution samples have almost identical changes in properties when exposed to different sterilization methods, and similar cooling rates. The data shown throughout this investigation confirms that manipulation of printing parameters can result in an object with comparable material properties to that created through traditional manufacturing methods.

  8. Enhanced zero-bias conductance peak and splitting at mesoscopic interfaces between an s-wave superconductor and a 3D Dirac semimetal

    NASA Astrophysics Data System (ADS)

    Aggarwal, Leena; Gayen, Sirshendu; Das, Shekhar; Thakur, Gohil S.; Ganguli, Ashok K.; Sheet, Goutam

    2016-12-01

    Mesoscopic point contacts between elemental metals and the topological 3D Dirac semimetal Cd3As2 have been recently shown to be superconducting with unconventional pairing while Cd3As2 itself does not superconduct. Here we show that the same superconducting phase at mesoscopic interfaces on Cd3As2 can be induced with a known conventional superconductor Nb where a pronounced zero-bias conductance peak is observed which undergoes splitting in energy under certain conditions. The observations are consistent with the theory of the emergence of Andreev bound states due to the presence of a pair potential with broken time reversal symmetry. The data also indicate the possibility of Majorana bound states as expected at the interfaces between s-wave superconductors and topologically non-trivial materials with a high degree of spin-orbit coupling.

  9. The effect of anisotropic heat transport on magnetic islands in 3-D configurations

    SciTech Connect

    Schlutt, M. G.; Hegna, C. C.

    2012-08-15

    An analytic theory of nonlinear pressure-induced magnetic island formation using a boundary layer analysis is presented. This theory extends previous work by including the effects of finite parallel heat transport and is applicable to general three dimensional magnetic configurations. In this work, particular attention is paid to the role of finite parallel heat conduction in the context of pressure-induced island physics. It is found that localized currents that require self-consistent deformation of the pressure profile, such as resistive interchange and bootstrap currents, are attenuated by finite parallel heat conduction when the magnetic islands are sufficiently small. However, these anisotropic effects do not change saturated island widths caused by Pfirsch-Schlueter current effects. Implications for finite pressure-induced island healing are discussed.

  10. Finite Gyroradius Effects in the Plasma Environment Near Titan: 3D Hybrid Modeling of the T5 Encounter

    NASA Astrophysics Data System (ADS)

    Simpson, D. G.; Lipatov, A. S.; Sittler, E. C.; Cooper, J. F.; Hartle, R. E.; Sarantos, M.

    2012-12-01

    In this report we discuss the results of a 3D hybrid modeling of the interaction between Saturn's magnetosphere and Titan's atmosphere/ionosphere for the T5 encounter. The T5 flyby is the only encounter when the two main ionizing sources of Titan's atmosphere, solar radiation and corotating plasma, align quasi-anti-parallel. The model is based on recent analysis of the Cassini Plasma Spectrometer (CAPS) and the Cassini Ion and Neutral Mass Spectrometer (INMS) measurements during the T5 flyby through Titan's ram-side and polar ionosphere [1,2]. Magnetic field data was used from the MAG instrument [3]. In our model the background ions (O+, H+), all pickup ions, and ionospheric ions are considered as a particles, whereas the electrons are described as a fluid (see e.g. [4]). Inhomogeneous photoionization (in the dayside ionosphere), electron-impact ionization, and charge exchange are included in our model. The temperature of the background electrons and pickup electrons was also incorporated into the generalized Ohm's law. We also take into account collisions between ions and neutrals. In our hybrid simulations we use Chamberlain profiles for the exosphere's components. The moon is considered as a weakly conducting body. The first results of our hybrid modeling show a strong asymmetry in the background (H+, O+) and pickup (H2+, N2+, CH4+) ion density profiles. Such strong asymmetry cannot be explained by a single-fluid multi-species 3D MHD model [5], which includes complex chemistry but does not produce finite gyroradius and kinetic effects. References [1] Sittler, et al., Energy Deposition Processes in Titan's Atmosphere and Its Induced Magnetosphere. In: Titan from Cassini-Huygens, Brown, R.H., Lebreton, J.P., Waite, J.H., Eds., Springer, (Dordrecht, Heidelberg, London, New York), pp. 393-455, 2010. [2] Agren, K., et al., On magnetosphere electron impact ionization and dynamics in Titan's ram-side and polar ionosphere -- a Cassini case study, Ann. Geophys., 25, 2359

  11. Effect of nitrogen availability on the poly-3-D-hydroxybutyrate accumulation by engineered Saccharomyces cerevisiae.

    PubMed

    Portugal-Nunes, Diogo J; Pawar, Sudhanshu S; Lidén, Gunnar; Gorwa-Grauslund, Marie F

    2017-12-01

    Poly-3-D-hydroxybutyrate (or PHB) is a polyester which can be used in the production of biodegradable plastics from renewable resources. It is naturally produced by several bacteria as a response to nutrient starvation in the excess of a carbon source. The yeast Saccharomyces cerevisiae could be an alternative production host as it offers good inhibitor tolerance towards weak acids and phenolic compounds and does not depolymerize the produced PHB. As nitrogen limitation is known to boost the accumulation of PHB in bacteria, the present study aimed at investigating the effect of nitrogen availability on PHB accumulation in two recombinant S. cerevisiae strains harboring different xylose consuming and PHB producing pathways: TMB4443 expressing an NADPH-dependent acetoacetyl-CoA reductase and a wild-type S. stipitis XR with preferential use of NADPH and TMB4425 which expresses an NADH-dependent acetoacetyl-CoA reductase and a mutated XR with a balanced affinity for NADPH/NADH. TMB4443 accumulated most PHB under aerobic conditions and with glucose as sole carbon source, whereas the highest PHB concentrations were obtained with TMB4425 under anaerobic conditions and xylose as carbon source. In both cases, the highest PHB contents were obtained with high availability of nitrogen. The major impact of nitrogen availability was observed in TMB4425, where a 2.7-fold increase in PHB content was obtained. In contrast to what was observed in natural PHB-producing bacteria, nitrogen deficiency did not improve PHB accumulation in S. cerevisiae. Instead the excess available carbon from xylose was shunted into glycogen, indicating a significant gluconeogenic activity on xylose.

  12. Effect of Kayak Ergometer Elastic Tension on Upper Limb EMG Activity and 3D Kinematics.

    PubMed

    Fleming, Neil; Donne, Bernard; Fletcher, David

    2012-01-01

    Despite the prevalence of shoulder injury in kayakers, limited published research examining associated upper limb kinematics and recruitment patterns exists. Altered muscle recruitment patterns on-ergometer vs. on-water kayaking were recently reported, however, mechanisms underlying changes remain to be elucidated. The current study assessed the effect of ergometer recoil tension on upper limb recruitment and kinematics during the kayak stroke. Male kayakers (n = 10) performed 4 by 1 min on-ergometer exercise bouts at 85%VO2max at varying elastic recoil tension; EMG, stroke force and three-dimensional 3D kinematic data were recorded. While stationary recoil forces significantly increased across investigated tensions (125% increase, p < 0.001), no significant differences were detected in assessed force variables during the stroke cycle. In contrast, increasing tension induced significantly higher Anterior Deltoid (AD) activity in the latter stages (70 to 90%) of the cycle (p < 0.05). No significant differences were observed across tension levels for Triceps Brachii or Latissimus Dorsi. Kinematic analysis revealed that overhead arm movements accounted for 39 ± 16% of the cycle. Elbow angle at stroke cycle onset was 144 ± 10°; maximal elbow angle (151 ± 7°) occurred at 78 ± 10% into the cycle. All kinematic markers moved to a more anterior position as tension increased. No significant change in wrist marker elevation was observed, while elbow and shoulder marker elevations significantly increased across tension levels (p < 0.05). In conclusion, data suggested that kayakers maintained normal upper limb kinematics via additional AD recruitment despite ergometer induced recoil forces. Key pointsKayak ergometer elastic tension significantly alters Anterior Deltoid recruitment patterns.Kayakers maintain optimal arm kinematics despite changing external forces via altered shoulder muscle recruitment.Overhead arm movements account for a high proportion of the kayak

  13. Effect of Kayak Ergometer Elastic Tension on Upper Limb EMG Activity and 3D Kinematics

    PubMed Central

    Fleming, Neil; Donne, Bernard; Fletcher, David

    2012-01-01

    Despite the prevalence of shoulder injury in kayakers, limited published research examining associated upper limb kinematics and recruitment patterns exists. Altered muscle recruitment patterns on-ergometer vs. on-water kayaking were recently reported, however, mechanisms underlying changes remain to be elucidated. The current study assessed the effect of ergometer recoil tension on upper limb recruitment and kinematics during the kayak stroke. Male kayakers (n = 10) performed 4 by 1 min on-ergometer exercise bouts at 85%VO2max at varying elastic recoil tension; EMG, stroke force and three-dimensional 3D kinematic data were recorded. While stationary recoil forces significantly increased across investigated tensions (125% increase, p < 0.001), no significant differences were detected in assessed force variables during the stroke cycle. In contrast, increasing tension induced significantly higher Anterior Deltoid (AD) activity in the latter stages (70 to 90%) of the cycle (p < 0.05). No significant differences were observed across tension levels for Triceps Brachii or Latissimus Dorsi. Kinematic analysis revealed that overhead arm movements accounted for 39 ± 16% of the cycle. Elbow angle at stroke cycle onset was 144 ± 10°; maximal elbow angle (151 ± 7°) occurred at 78 ± 10% into the cycle. All kinematic markers moved to a more anterior position as tension increased. No significant change in wrist marker elevation was observed, while elbow and shoulder marker elevations significantly increased across tension levels (p < 0.05). In conclusion, data suggested that kayakers maintained normal upper limb kinematics via additional AD recruitment despite ergometer induced recoil forces. Key pointsKayak ergometer elastic tension significantly alters Anterior Deltoid recruitment patterns.Kayakers maintain optimal arm kinematics despite changing external forces via altered shoulder muscle recruitment.Overhead arm movements account for a high proportion of the kayak

  14. Effects of inhomogeneity at stagnation in 3D simulations of ICF implosions

    NASA Astrophysics Data System (ADS)

    Appelbe, Brian

    2016-10-01

    The stagnation phase of an ICF implosion is characterized by a hotspot and dense fuel layer that are spatially and temporally inhomogeneous. Perturbation growth during the implosion results in significant asymmetry at stagnation while the hotspot size, density and temperature change rapidly, even in non-igniting capsules. Diagnosing these inhomogeneities is necessary to increase yield in ICF experiments. In this work, 3D radiation hydrodynamic simulations of perturbed indirect drive ICF capsules are carried out using the CHIMERA code. During the stagnation phase a suite of novel and computationally efficient simulation tools are used to produce synthetic time-resolved neutron spectra and images. These tools allow a detailed study of the effects of hotspot inhomogeneities on diagnostic signals. Results show that the burn-averaged ion temperature drops rapidly during thermonuclear burn as the hotspot evolves from a localised, shock-heated region to a more massive, non-uniform plasma. Primary DD and DT neutron spectra show that there is significant residual bulk fluid motion at stagnation, complicating the measurement of ion temperature. Different perturbation modes cause different levels of anisotropic spectra shifts and broadening. However, in all cases the discrepancies between the DD and DT spectra are a reliable indicator of residual motion at stagnation. The simulations are used to examine the relationship between neutron scattering and areal density (ρR). Three measures of areal density are simulated: downscattered neutron ratio, attenuated primary neutron yield and nT backscatter edge. Each of these diagnoses the magnitude and anisotropy of the ρR with varying success, with accuracy decreasing for higher mode perturbations. Contributions to the neutron energy spectra from T +T reactions, secondary DT reactions and deuteron break-up are also evaluated.

  15. The effect of pose variability and repeated reliability of segmental centres of mass acquisition when using 3D photonic scanning.

    PubMed

    Chiu, Chuang-Yuan; Pease, David L; Sanders, Ross H

    2016-12-01

    Three-dimensional (3D) photonic scanning is an emerging technique to acquire accurate body segment parameter data. This study established the repeated reliability of segmental centres of mass when using 3D photonic scanning (3DPS). Seventeen male participants were scanned twice by a 3D whole-body laser scanner. The same operators conducted the reconstruction and segmentation processes to obtain segmental meshes for calculating the segmental centres of mass. The segmental centres of mass obtained from repeated 3DPS were compared by relative technical error of measurement (TEM). Hypothesis tests were conducted to determine the size of change required for each segment to be determined a true variation. The relative TEMs for all segments were less than 5%. The relative changes in centres of mass at ±1.5% for most segments can be detected (p < 0.05). The arm segments which are difficult to keep in the same scanning pose generated more error than other segments. Practitioner Summary: Three-dimensional photonic scanning is an emerging technique to acquire body segment parameter data. This study established the repeated reliability of segmental centres of mass when using 3D photonic scanning and emphasised that the error for arm segments need to be considered while using this technique to acquire centres of mass.

  16. 3D ultrasound estimation of the effective volume for popliteal block at the level of division.

    PubMed

    Sala-Blanch, X; Franco, J; Bergé, R; Marín, R; López, A M; Agustí, M

    2017-03-01

    Local anaesthetic injection between the tibial and commmon peroneal nerves within connective tissue sheath results in a predictable diffusion and allows for a reduction in the volume needed to achieve a consistent sciatic popliteal block. Using 3D ultrasound volumetric acquisition, we quantified the visible volume in contact with the nerve along a 5cm segment.

  17. 3D-2D registration for surgical guidance: effect of projection view angles on registration accuracy.

    PubMed

    Uneri, A; Otake, Y; Wang, A S; Kleinszig, G; Vogt, S; Khanna, A J; Siewerdsen, J H

    2014-01-20

    An algorithm for intensity-based 3D-2D registration of CT and x-ray projections is evaluated, specifically using single- or dual-projection views to provide 3D localization. The registration framework employs the gradient information similarity metric and covariance matrix adaptation evolution strategy to solve for the patient pose in six degrees of freedom. Registration performance was evaluated in an anthropomorphic phantom and cadaver, using C-arm projection views acquired at angular separation, Δθ, ranging from ∼0°-180° at variable C-arm magnification. Registration accuracy was assessed in terms of 2D projection distance error and 3D target registration error (TRE) and compared to that of an electromagnetic (EM) tracker. The results indicate that angular separation as small as Δθ ∼10°-20° achieved TRE <2 mm with 95% confidence, comparable or superior to that of the EM tracker. The method allows direct registration of preoperative CT and planning data to intraoperative fluoroscopy, providing 3D localization free from conventional limitations associated with external fiducial markers, stereotactic frames, trackers and manual registration.

  18. 3D-2D registration for surgical guidance: effect of projection view angles on registration accuracy

    NASA Astrophysics Data System (ADS)

    Uneri, A.; Otake, Y.; Wang, A. S.; Kleinszig, G.; Vogt, S.; Khanna, A. J.; Siewerdsen, J. H.

    2014-01-01

    An algorithm for intensity-based 3D-2D registration of CT and x-ray projections is evaluated, specifically using single- or dual-projection views to provide 3D localization. The registration framework employs the gradient information similarity metric and covariance matrix adaptation evolution strategy to solve for the patient pose in six degrees of freedom. Registration performance was evaluated in an anthropomorphic phantom and cadaver, using C-arm projection views acquired at angular separation, Δθ, ranging from ˜0°-180° at variable C-arm magnification. Registration accuracy was assessed in terms of 2D projection distance error and 3D target registration error (TRE) and compared to that of an electromagnetic (EM) tracker. The results indicate that angular separation as small as Δθ ˜10°-20° achieved TRE <2 mm with 95% confidence, comparable or superior to that of the EM tracker. The method allows direct registration of preoperative CT and planning data to intraoperative fluoroscopy, providing 3D localization free from conventional limitations associated with external fiducial markers, stereotactic frames, trackers and manual registration.

  19. Effects of Training Method and Gender on Learning 2D/3D Geometry

    ERIC Educational Resources Information Center

    Khairulanuar, Samsudin; Nazre, Abd Rashid; Jamilah, H.; Sairabanu, Omar Khan; Norasikin, Fabil

    2010-01-01

    This article reports the findings of an experimental study involving 36 primary school students (16 girls, 20 boys, Mean age = 9.5 years, age range: 8-10 years) in geometrical understanding of 2D and 3D objects. Students were assigned into two experimental groups and one control group based on a stratified random sampling procedure. The first…

  20. Representing 3-D cloud radiation effects in two-stream schemes: 1. Longwave considerations and effective cloud edge length

    NASA Astrophysics Data System (ADS)

    Schäfer, Sophia A. K.; Hogan, Robin J.; Klinger, Carolin; Chiu, J. Christine; Mayer, Bernhard

    2016-07-01

    Current weather and climate models neglect 3-D radiative transfer through cloud sides, which can change the cloud radiative effect (CRE) significantly. This two-part paper describes the development of the SPeedy Algorithm for Radiative TrAnsfer through CloUd Sides (SPARTACUS) to capture these effects efficiently in a two-stream radiation scheme for use in global models. The present paper concerns the longwave spectral region, where not much work has been done previously, although the limited previous work has suggested that radiative transfer through cloud sides increases the longwave surface CRE of shallow cumulus by around 30%. To assist the development of a longwave capability for SPARTACUS, we use a reference case of an isolated, isothermal, optically thick, cubic cloud in vacuum, for which 3-D effects increase CRE by exactly 200%. It is shown that for any cloud shape, the 3-D effect can be represented in SPARTACUS provided that correct account is made for (1) the effective zenith angle of diffuse radiation emitted from a cloud, (2) the spatial distribution of fluxes in the cloud, (3) cloud clustering that enhances the interception of emitted radiation by neighboring clouds, and (4) radiative smoothing leading to the effective cloud edge length being less than the measured value. We find empirically that the circumference of an ellipse fitted to a horizontal cross section through a cumulus cloud provides a good estimate of the radiatively effective cloud edge length, which provides some guidance to how cloud observations could be analyzed to extract their most important properties for radiation.

  1. The Effect of Scattering on the Temperature Stratification of 3D Model Atmospheres of Metal-Poor Red Giants

    NASA Astrophysics Data System (ADS)

    Collet, Remo; Hayek, Wolfgang; Asplund, Martin

    2011-08-01

    We study the effects of different approximations of scattering in 3D radiation-hydrodynamics simulations on the photospheric temperature stratification of metal-poor red giant stars. We find that assuming a Planckian source function and neglecting the contribution of scattering to extinction in optically thin layers provides a good approximation of the effects of coherent scattering on the photospheric temperature balance.

  2. Biomimicry 3D gastrointestinal spheroid platform for the assessment of toxicity and inflammatory effects of zinc oxide nanoparticles.

    PubMed

    Chia, Sing Ling; Tay, Chor Yong; Setyawati, Magdiel I; Leong, David T

    2015-02-11

    Our current mechanistic understanding on the effects of engineered nanoparticles (NPs) on cellular physiology is derived mainly from 2D cell culture studies. However, conventional monolayer cell culture may not accurately model the mass transfer gradient that is expected in 3D tissue physiology and thus may lead to artifactual experimental conclusions. Herein, using a micropatterned agarose hydrogel platform, the effects of ZnO NPs (25 nm) on 3D colon cell spheroids of well-defined sizes are examined. The findings show that cell dimensionality plays a critical role in governing the spatiotemporal cellular outcomes like inflammatory response and cytotoxicity in response to ZnO NPs treatment. More importantly, ZnO NPs can induce different modes of cell death in 2D and 3D cell culture systems. Interestingly, the outer few layers of cells in 3D model could only protect the inner core of cells for a limited time and periodically slough off from the spheroids surface. These findings suggest that toxicological conclusions made from 2D cell models might overestimate the toxicity of ZnO NPs. This 3D cell spheroid model can serve as a reproducible platform to better reflect the actual cell response to NPs and to study a more realistic mechanism of nanoparticle-induced toxicity.

  3. Evaluation of the effectiveness of 3D vascular stereoscopic models in anatomy instruction for first year medical students.

    PubMed

    Cui, Dongmei; Wilson, Timothy D; Rockhold, Robin W; Lehman, Michael N; Lynch, James C

    2017-01-01

    The head and neck region is one of the most complex areas featured in the medical gross anatomy curriculum. The effectiveness of using three-dimensional (3D) models to teach anatomy is a topic of much discussion in medical education research. However, the use of 3D stereoscopic models of the head and neck circulation in anatomy education has not been previously studied in detail. This study investigated whether 3D stereoscopic models created from computed tomographic angiography (CTA) data were efficacious teaching tools for the head and neck vascular anatomy. The test subjects were first year medical students at the University of Mississippi Medical Center. The assessment tools included: anatomy knowledge tests (prelearning session knowledge test and postlearning session knowledge test), mental rotation tests (spatial ability; presession MRT and postsession MRT), and a satisfaction survey. Results were analyzed using a Wilcoxon rank-sum test and linear regression analysis. A total of 39 first year medical students participated in the study. The results indicated that all students who were exposed to the stereoscopic 3D vascular models in 3D learning sessions increased their ability to correctly identify the head and neck vascular anatomy. Most importantly, for students with low-spatial ability, 3D learning sessions improved postsession knowledge scores to a level comparable to that demonstrated by students with high-spatial ability indicating that the use of 3D stereoscopic models may be particularly valuable to these students with low-spatial ability. Anat Sci Educ 10: 34-45. © 2016 American Association of Anatomists.

  4. 3D porous sol-gel matrix incorporated microdevice for effective large volume cell sample pretreatment.

    PubMed

    Lee, Chan Joo; Jung, Jae Hwan; Seo, Tae Seok

    2012-06-05

    In this study, we demonstrated an effective sample pretreatment microdevice that could perform the capture, purification, and release of pathogenic bacteria with a large-volume sample and at a high speed and high-capture yield. We integrated a sol-gel matrix into the microdevice which forms three-dimensional (3D) micropores for the cell solution to pass through and provides a large surface area for the immobilization of antibodies to capture the target Staphylococcus aureus (S. aureus) cells. The antibody was linked to the surface of the sol-gel via a photocleavable linker, allowing the cell-captured antibody moiety to be released by UV irradiation. In addition to the optimization of the antibody immobilization and UV cleavage processes, the cell-capture efficiency was maximized by controlling the sample flow rate with a pumping scheme (3 steps, 5 steps: 3 steps with one flutter step, 7 steps: 3 steps with two flutter steps) and the pumping time (100, 200, and 300 ms). A quantitative capture analysis was performed by targeting a specific gene site of protein A of S. aureus in real-time PCR (RT-PCR). While the 3-step process with an actuation time of 100 ms showed the fastest flow rate (1 mL sample processing time in 10 min), the pumping scheme with the 7-step process and the 300 ms actuation time revealed the highest cell-capture efficiency. A limit of detection study with the 7-step and the 300 ms pumping scheme demonstrated that 100 cells per 100 μL were detected with a 70% yield, and even a single cell could be analyzed via on-chip sample preparation. Thus, our novel sol-gel based microdevice was proven more cost-effective, simple, and efficient in terms of its sample pretreatment ability compared to the use of a conventional 2D flat microdevice. This proposed sample pretreatment device can be further incorporated to an analytical functional unit to realize a micrototal analysis system (μTAS) with sample-in-answer-out capability in the fields of biomedical

  5. Effects of Na+ and He+ pickup ions on the lunar plasma environment: 3D hybrid modeling

    NASA Astrophysics Data System (ADS)

    Lipatov, A. S.; Cooper, J. F.; Sittler, E. C.; Hartle, R. E.; Sarantos, M.

    2011-12-01

    The hybrid kinetic model used here supports comprehensive simulation of the interaction between different spatial and energetic elements of the moon-solar wind-magnetosphere of the Earth system. There is a set of MHD,kinetic, hybrid, drift kinetic, electrostatic and full kinetic modeling of the lunar plasma environment [1]. However, observations show the existence of several species of the neutrals and pickup ions like Na, He, K, O etc., (see e.g., [2,3,4]). The solar wind parameters are chosen from the ARTEMIS observations [5]. The Na+, He+ lunar exosphere's parameters are chosen from [6,7]. The hybrid kinetic model allows us to take into account the finite gyroradius effects of pickup ions and to correctly estimate the ions velocity distribution and the fluxes along the magnetic field, and on the lunar surface. Modeling shows the formation of the asymmetric Mach cone, the structuring of the pickup ion tails, and presents another type of lunar-solar wind interaction. We will compare the results of our modeling with observed distributions. References [1] Lipatov, A.S., and Cooper, J.F., Hybrid kinetic modeling of the Lunar plasma environment: Past, present and future. In: Lunar Dust, Plasma and Atmosphere: The Next Steps, January 27-29, 2010, Boulder, Colorado, Abstracts/lpa2010.colorado.edu/. [2] Potter, A.E., and Morgan, T.H., Discovery of sodium and potassium vapor in the atmosphere of the Moon, Science, 241, 675-680, doi:10.1126/science.241.4866.675, 1988. [3] Tyler, A.L., et al., Observations of sodium in the tenuous lunar atmosphere, Geophys. Res. Lett., 15(10), 1141-1144, doi:10.1029/GL015i010p01141, 1988. [4] Tanaka, T., et al., First in situ observation of the Moon-originating ions in the Earth's Magnetosphere by MAP-PACE on SELENE (KAGUYA), Geophys. Res. Lett., 36, L22106, doi:10.1029/2009GL040682, 2009. [5] Wiehle, S., et al., First Lunar Wake Passage of ARTEMIS: Discrimination of Wake Effects and Solar Wind Fluctuations by 3D Hybrid Simulations, Planet

  6. Synthesis, Structure, Multiband Optical, and Electrical Conductive Properties of a 3D Open Cubic Framework Based on [Cu8Sn6S24](z-) Clusters.

    PubMed

    Zhang, Xian; Wang, Qiuran; Ma, Zhimin; He, Jianqiao; Wang, Zhe; Zheng, Chong; Lin, Jianhua; Huang, Fuqiang

    2015-06-01

    Two compounds with the formulas of Na4Cu32Sn12S48·4H2O and K11Cu32Sn12S48·4H2O were synthesized via flux (with thiourea as reactive flux) and hydrothermal method, respectively. The black crystals of Na4Cu32Sn12S48·4H2O and K11Cu32Sn12S48·4H2O both crystallize in the cubic space group of Fm3̅c with the cell constants a = 17.921(2) Å and a = 18.0559(6) Å, respectively. The crystal structures feature a 3D open-framework with the unique [Cu8Sn6S24](z-) (z = 13 for Na4Cu32Sn12S48·4H2O; z = 14.75 for K11Cu32Sn12S48·4H2O) clusters acting as building blocks. The [Cu8Sn6S24](z-) cluster of the Th symmetry is built up by eight [CuS3] triangles and six [SnS4] tetrahedra. The powder samples were investigated by X-ray diffraction and optical absorption measurements. Both phase-pure compounds show multiabsorption character with a main absorption edge (2.0 eV for Na4Cu32Sn12S48·4H2O and 1.9 eV for K11Cu32Sn12S48·4H2O) and an additional absorption peak (1.61 eV for Na4Cu32Sn12S48·4H2O and 1.52 eV for K11Cu32Sn12S48·4H2O), which are perfectly consistent with the first-principle calculation results. The analyses of the density of states further reveal that the two optical absorption bands in each compound are attributed to the two transitions of Cu-3d-S-3p → Sn-5s. The multiband nature of two compounds also enhances photocatalytic activity under visible light irradiation, with which the degradation of methyl blue over Na4Cu32Sn12S48·4H2O reached 100% in 3 h. The 3D open-framework features also facilitate the ionic conductivity nature of the Na4Cu32Sn12S48·4H2O compound, which achieved ∼10(-5) S/cm at room temperature.

  7. Effects of 3-D Visualization of Groundwater Modeling for Water Resource Decision Making

    NASA Astrophysics Data System (ADS)

    Block, J. L.; Arrowsmith, R.

    2006-12-01

    The rise of 3-D visualization hardware and software technology provides important opportunities to advance scientific and policy research. Although the petroleum industry has used immersive 3-D technology since the early 1990's for the visualization of geologic data among experts, there has been little use of this technology for decision making. The Decision Theater at ASU is a new facility using immersive visualization technology designed to combine scientific research at the university with policy decision making in the community. I document a case study in the use of 3-D immersive technology for water resource management in Arizona. Since the turn of the 20th century, natural hydrologic processes in the greater Phoenix region (Salt River Valley) have been shut down via the construction of dams, canals, wells, water treatment plants, and recharge facilities. Water from rivers that once naturally recharged the groundwater aquifer have thus been diverted while continuing groundwater outflow from wells has drawn the aquifer down hundreds of feet. MODFLOW is used to simulate groundwater response to the different water management decisions which impact the artificial and natural inflow and outflow. The East Valley Water Forum, a partnership of water providers east of Phoenix, used the 3-D capabilities of the Decision Theater to build visualizations of the East Salt River Valley groundwater system based on MODFLOW outputs to aid the design of a regional groundwater management plan. The resulting visualizations are now being integrated into policy decisions about long term water management. I address challenges in visualizing scientific information for policy making and highlight the roles of policy actors, specifically geologists, computer scientists, and political decision makers, involved in designing the visualizations. The results show that policy actors respond differently to the 3-D visualization techniques based on their experience, background, and objectives

  8. Light-Driven Overall Water Splitting Enabled by a Photo-Dember Effect Realized on 3D Plasmonic Structures.

    PubMed

    Chen, Min; Gu, Jiajun; Sun, Cheng; Zhao, Yixin; Zhang, Ruoxi; You, Xinyuan; Liu, Qinglei; Zhang, Wang; Su, Yishi; Su, Huilan; Zhang, Di

    2016-07-26

    Photoelectric conversion driven by sunlight has a broad range of energy/environmental applications (e.g., in solar cells and water splitting). However, difficulties are encountered in the separation of photoexcited charges. Here, we realize a long-range (∼1.5 μm period) electric polarization via asymmetric localization of surface plasmons on a three-dimensional silver structure (3D-Ag). This visible-light-responsive effect-the photo-Dember effect, can be analogous to the thermoelectric effect, in which hot carriers are thermally generated instead of being photogenerated. The induced electric field can efficiently separate photogenerated charges, enabling sunlight-driven overall water splitting on a series of dopant-free commercial semiconductor particles (i.e., ZnO, CeO2, TiO2, and WO3) once they are combined with the 3D-Ag substrate. These photocatalytic processes can last over 30 h on 3D-Ag+ZnO, 3D-Ag+CeO2, and 3D-Ag+TiO2, thus demonstrating good catalytic stability for these systems. Using commercial WO3 powder as a reference, the amount of O2 generated with 3D-Ag+CeO2 surpasses even its recently reported counterpart in which sacrificial reagents had to be involved to run half-reactions. This plasmon-mediated charge separation strategy provides an effective way to improve the efficiency of photoelectric energy conversion, which can be useful in photovoltaics and photocatalysis.

  9. Suppressed 3D conductivity in Mn doped Cu0.5Tl0.5Ba2Ca2-yMnyCu3O10-δ superconductors

    NASA Astrophysics Data System (ADS)

    Qurat-ul-Ain, Khan, Nawazish A.

    2013-04-01

    We have synthesised Mn-doped Cu0.5Tl0.5Ba2(Ca2-yMny)Cu3O10-δ superconducting samples and studied their Fluctuation Induced Conductivity (FIC) analysis. The Tc(R = 0) and magnitude of diamagnetism are suppressed with increased Mn-doping in the final compound. FIC analyses have shown a suppression of 3D Lawrence and Doniach (LD) regime and a significant enhancement of 2D LD regime of Mn-doping of y = 0.35. In the sample with Mn-doping of y = 0.5, the 3D LD regime vanishes altogether and only 2D LD regime is observed, showing the confinement of superconductivity in the two dimensional planes. The coherence length along the c-axis and the Fermi velocity of the carriers are suppressed with increased Mn doping. Using the Ginzburg-Landau (GL) number [NG] and GL equations, the thermodynamic critical magnetic field Bc(0), the lower critical field Bc1(0), the upper critical field Bc2(0), the critical current density Jc(0), and penetration depth λp.d are determined. The values of critical fields Bc(0) and Bc1(0) increases, despite suppression in the Tc(R = 0) with increased Mn-doping. The values of Jc(0), the penetration depth Λp.d, and inter-layer coupling are suppressed with enhanced Mn-doping. These observations suggested that Mn ions act as sub-nano-scale pinning centers between the CuO2 planes and their presence at the Ca-sites promote the de-coupling of CuO2 planes.

  10. Spontaneous organization of uniform CeO2 nanoflowers by 3D oriented attachment in hot surfactant solutions monitored with an in situ electrical conductance technique.

    PubMed

    Zhou, Huan-Ping; Zhang, Ya-Wen; Mai, Hao-Xin; Sun, Xiao; Liu, Qiang; Song, Wei-Guo; Yan, Chun-Hua

    2008-01-01

    Uniform CeO(2) nanoflowers were synthesized by rapid thermolysis of (NH(4))(2)Ce(NO(3))(6) in oleic acid (OA)/oleylamine (OM), by a unique 3D oriented-attachment mechanism. CeO(2) nanoflowers with controlled shape (cubic, four-petaled, and starlike) and tunable size (10-40 nm) were obtained by adjusting the reaction conditions including solvent composition, precursor concentration, reaction temperature, and reaction time. The nanoflower growth mechanism was investigated by in situ electrical conductance measurements, transmission electron microscopy, and UV/Vis spectroscopy. The CeO(2) nanoflowers are likely formed in two major steps, that is, initial formation of ceria cluster particles capped with various ligands (e.g., OA, OM, and NO(3) (-)) via hydrolysis of (NH(4))(2)Ce(NO(3))(6) at temperatures in the range 140-220 degrees C, and subsequent spontaneous organization of the primary particles into nanoflowers by 3D oriented attachment, due to a rapid decrease in surface ligand coverage caused by sudden decomposition of the precursor at temperatures above 220 degrees C in a strong redox reaction. After calcination at 400 degrees C for 4 h the 33.8 nm CeO(2) nanoflowers have a specific surface area as large as 156 m(2) g(-1) with high porosity, and they are highly active for conversion of CO to CO(2) in the low temperature range of 200-400 degrees C. The present approach has also been extended to the preparation of other transition metal oxide (CoO, NiO, and CuO(x)) nanoflowers.

  11. An aerial 3D printing test mission

    NASA Astrophysics Data System (ADS)

    Hirsch, Michael; McGuire, Thomas; Parsons, Michael; Leake, Skye; Straub, Jeremy

    2016-05-01

    This paper provides an overview of an aerial 3D printing technology, its development and its testing. This technology is potentially useful in its own right. In addition, this work advances the development of a related in-space 3D printing technology. A series of aerial 3D printing test missions, used to test the aerial printing technology, are discussed. Through completing these test missions, the design for an in-space 3D printer may be advanced. The current design for the in-space 3D printer involves focusing thermal energy to heat an extrusion head and allow for the extrusion of molten print material. Plastics can be used as well as composites including metal, allowing for the extrusion of conductive material. A variety of experiments will be used to test this initial 3D printer design. High altitude balloons will be used to test the effects of microgravity on 3D printing, as well as parabolic flight tests. Zero pressure balloons can be used to test the effect of long 3D printing missions subjected to low temperatures. Vacuum chambers will be used to test 3D printing in a vacuum environment. The results will be used to adapt a current prototype of an in-space 3D printer. Then, a small scale prototype can be sent into low-Earth orbit as a 3-U cube satellite. With the ability to 3D print in space demonstrated, future missions can launch production hardware through which the sustainability and durability of structures in space will be greatly improved.

  12. Effect of geometry on drug release from 3D printed tablets.

    PubMed

    Goyanes, Alvaro; Robles Martinez, Pamela; Buanz, Asma; Basit, Abdul W; Gaisford, Simon

    2015-10-30

    The aim of this work was to explore the feasibility of combining hot melt extrusion (HME) with 3D printing (3DP) technology, with a view to producing different shaped tablets which would be otherwise difficult to produce using traditional methods. A filament extruder was used to obtain approx. 4% paracetamol loaded filaments of polyvinyl alcohol with characteristics suitable for use in fused-deposition modelling 3DP. Five different tablet geometries were successfully 3D-printed-cube, pyramid, cylinder, sphere and torus. The printing process did not affect the stability of the drug. Drug release from the tablets was not dependent on the surface area but instead on surface area to volume ratio, indicating the influence that geometrical shape has on drug release. An erosion-mediated process controlled drug release. This work has demonstrated the potential of 3DP to manufacture tablet shapes of different geometries, many of which would be challenging to manufacture by powder compaction.

  13. Effective 3D protein structure prediction with local adjustment genetic-annealing algorithm.

    PubMed

    Zhang, Xiao-Long; Lin, Xiao-Li

    2010-09-01

    The protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing the energy function. The protein folding structure prediction is computationally challenging and has been shown to be NP-hard problem when the 3D off-lattice AB model is employed. In this paper, the local adjustment genetic-annealing (LAGA) algorithm was used to search the ground state of 3D offlattice AB model for protein folding structure. The algorithm included an improved crossover strategy and an improved mutation strategy, where a local adjustment strategy was also used to enhance the searching ability. The experiments were carried out with the Fibonacci sequences. The experimental results demonstrate that the LAGA algorithm appears to have better performance and accuracy compared to the previous methods.

  14. Cloud 3D Effects Evidenced in Landsat Power Spectra and Autocorrelation Functions

    NASA Technical Reports Server (NTRS)

    Oreopoulos, Lazaros; Marshak, Alexander; Cahalan, Robert F.; Wen, Guoyong

    1999-01-01

    the spectral signatures of decorrelation between reflectance and optical depth at large scales becoming stronger as the magnitude of cloud top variations increase. Finally, the usefulness of power spectral analysis in evaluating the skill of novel optical depth retrieval techniques in removing 3D radiative effects is demonstrated. New techniques using inverse Non-local Independent Pixel Approximation (NIPA) and Normalized Difference of Nadir Reflectivity (NDNR) yield optical depth fields which better match the scale-by-scale variability of the true optical depth field.

  15. Tetradecanuclearity in 3d-4f chemistry: relaxation and magnetocaloric effects in [NiLn] species.

    PubMed

    Canaj, Angelos B; Kalofolias, Dimitris A; Siczek, Milosz; Lis, Tadeusz; McNab, Robbie; Lorusso, Giulia; Inglis, Ross; Evangelisti, Marco; Milios, Constantinos J

    2017-03-14

    The employment of 2-amino-isobutyric acid, Haib, and 2-hydroxy-1-naphthaldehyde, Hnaphth, in Ni(II)/Ln(III) chemistry has led to the isolation and characterization of two new isostructural 3d-4f tetradecanuclear [NiLn] clusters (Ln = Gd(III), Dy(III)), with the Dy analogue displaying temperature and frequency dependent out-of-phase signals, and the Gd analogue showing interesting magnetocaloric properties.

  16. The Effect of Ultrasound Stimulation on the Cytoskeletal Organization of Chondrocytes Seeded In 3D Matrices

    PubMed Central

    Noriega, Sandra; Hasanova, Gulnara; Subramanian, Anuradha

    2013-01-01

    The impact of low intensity diffuse ultrasound (LIDUS) stimulation on the cytoskeletal organization of chondrocytes seeded in 3D scaffolds was evaluated. Chondrocytes seeded on 3D chitosan matrices were exposed to LIDUS at 5.0 MHz (~15kPa, 51-secs, 4-applications/day) in order to study the organization of actin, tubulin and vimentin. The results showed that actin presented a cytosolic punctuated distribution, tubulin presented a quasi parallel organization of microtubules whereas vimentin distribution was unaffected. Chondrocytes seeded on 3D scaffolds responded to US stimulation by the disruption of actin stress fibers and were sensitive to the presence of ROCK inhibitor (Y27632). The gene expression of ROCK-I, a key element in the formation of stress fibers and mDia1, was significantly up-regulated under the application of US. We conclude that the results of both the cytoskeletal analyses and gene expression support the argument that the presence of punctuated actin upon US stimulation was accompanied by the up-regulation of the RhoA/ROCK pathway. PMID:22987069

  17. 3D Bioprinting of complex channels-Effects of material, orientation, geometry, and cell embedding.

    PubMed

    Wüst, Silke; Müller, Ralph; Hofmann, Sandra

    2015-08-01

    Creating filled or hollow channels within 3D tissues has become increasingly important in tissue engineering. Channels can serve as vasculature enhancing medium perfusion or as conduits for nerve regeneration. The 3D biofabrication seems to be a promising method to generate these structures within 3D constructs layer-by-layer. In this study, geometry and interface of bioprinted channels were investigated with micro-computed tomography and fluorescent imaging. In filament printing, size and shape of printed channels are influenced by their orientation, which was analyzed by printing horizontally and vertically aligned channels, and by the ink, which was evaluated by comparing channels printed with an alginate-gelatin hydrogel or with an emulsion. The influence of geometry and cell-embedding in the hydrogel on feature size and shape was investigated by printing more complex channels. The generation of hollow channels, induced through leaching of a support phase, was monitored over time. Horizontally aligned channels provided 16× smaller cross-sectional areas than channels in vertical orientation. The smallest feature size of hydrogel filaments was twice as large compared to emulsion filaments. Feature size and shape depended on the geometry but did not alter when living cells were embedded. With that knowledge, channels can be consciously tailored to the particular needs.

  18. Conducting Effective Simulator Training.

    ERIC Educational Resources Information Center

    Gerling, Kenneth D.

    This paper describes the simulator phase of Commonwealth Edison's program for training and licensing operators of nuclear power stations. Topics covered include (1) preparing the students before starting the simulator phase; (2) the simulator schedule and the number of students that can be trained effectively in a class; (3) format and structure…

  19. Dirac Circles and Quantum Hall Effect in 3D Inversion-Symmetric Crystals

    NASA Astrophysics Data System (ADS)

    Wieder, Benjamin J.; Kim, Youngkuk; Kane, C. L.

    2015-03-01

    In the presence of inversion and time-reversal symmetries, materials with weak spin-orbit coupling may host topologically protected Dirac line nodes. A band inversion transition in these systems can produce a line node which closes on itself and forms a protected Dirac circle. The surfaces parallel to this circle host zero-energy puddles in momentum space which are flat if the inverting bands have the same effective mass. In cases with differing effective masses, the surface modes disperse, but the bulk Dirac circle remains gapless. Adding an external magnetic field perpendicular to this circle creates surface Landau levels, whose number can be controlled by tuning the field strength. When a new level is created or destroyed, the bulk becomes gapless and the zero-temperature bulk conductivity displays a sharp peak. The sequence of conductivity peaks describes an unusual manifestation of the integer quantum hall effect. We characterize surface and bulk transport as a function of magnetic field strength and in the presence of disorder.

  20. 3D Simulation Technology as an Effective Instructional Tool for Enhancing Spatial Visualization Skills in Apparel Design

    ERIC Educational Resources Information Center

    Park, Juyeon; Kim, Dong-Eun; Sohn, MyungHee

    2011-01-01

    The purpose of this study is to explore the effectiveness of 3D simulation technology for enhancing spatial visualization skills in apparel design education and further to suggest an innovative teaching approach using the technology. Apparel design majors in an introductory patternmaking course, at a large Midwestern University in the United…

  1. A coarse-grained model with implicit salt for RNAs: Predicting 3D structure, stability and salt effect

    SciTech Connect

    Shi, Ya-Zhou; Wang, Feng-Hua; Wu, Yuan-Yan; Tan, Zhi-Jie

    2014-09-14

    To bridge the gap between the sequences and 3-dimensional (3D) structures of RNAs, some computational models have been proposed for predicting RNA 3D structures. However, the existed models seldom consider the conditions departing from the room/body temperature and high salt (1M NaCl), and thus generally hardly predict the thermodynamics and salt effect. In this study, we propose a coarse-grained model with implicit salt for RNAs to predict 3D structures, stability, and salt effect. Combined with Monte Carlo simulated annealing algorithm and a coarse-grained force field, the model folds 46 tested RNAs (≤45 nt) including pseudoknots into their native-like structures from their sequences, with an overall mean RMSD of 3.5 Å and an overall minimum RMSD of 1.9 Å from the experimental structures. For 30 RNA hairpins, the present model also gives the reliable predictions for the stability and salt effect with the mean deviation ∼ 1.0 °C of melting temperatures, as compared with the extensive experimental data. In addition, the model could provide the ensemble of possible 3D structures for a short RNA at a given temperature/salt condition.

  2. The psychology of the 3D experience

    NASA Astrophysics Data System (ADS)

    Janicke, Sophie H.; Ellis, Andrew

    2013-03-01

    With 3D televisions expected to reach 50% home saturation as early as 2016, understanding the psychological mechanisms underlying the user response to 3D technology is critical for content providers, educators and academics. Unfortunately, research examining the effects of 3D technology has not kept pace with the technology's rapid adoption, resulting in large-scale use of a technology about which very little is actually known. Recognizing this need for new research, we conducted a series of studies measuring and comparing many of the variables and processes underlying both 2D and 3D media experiences. In our first study, we found narratives within primetime dramas had the power to shift viewer attitudes in both 2D and 3D settings. However, we found no difference in persuasive power between 2D and 3D content. We contend this lack of effect was the result of poor conversion quality and the unique demands of 3D production. In our second study, we found 3D technology significantly increased enjoyment when viewing sports content, yet offered no added enjoyment when viewing a movie trailer. The enhanced enjoyment of the sports content was shown to be the result of heightened emotional arousal and attention in the 3D condition. We believe the lack of effect found for the movie trailer may be genre-related. In our final study, we found 3D technology significantly enhanced enjoyment of two video games from different genres. The added enjoyment was found to be the result of an increased sense of presence.

  3. Evaluation of vision training using 3D play game

    NASA Astrophysics Data System (ADS)

    Kim, Jung-Ho; Kwon, Soon-Chul; Son, Kwang-Chul; Lee, Seung-Hyun

    2015-03-01

    The present study aimed to examine the effect of the vision training, which is a benefit of watching 3D video images (3D video shooting game in this study), focusing on its accommodative facility and vergence facility. Both facilities, which are the scales used to measure human visual performance, are very important factors for man in leading comfortable and easy life. This study was conducted on 30 participants in their 20s through 30s (19 males and 11 females at 24.53 ± 2.94 years), who can watch 3D video images and play 3D game. Their accommodative and vergence facility were measured before and after they watched 2D and 3D game. It turned out that their accommodative facility improved after they played both 2D and 3D games and more improved right after they played 3D game than 2D game. Likewise, their vergence facility was proved to improve after they played both 2D and 3D games and more improved soon after they played 3D game than 2D game. In addition, it was demonstrated that their accommodative facility improved to greater extent than their vergence facility. While studies have been so far conducted on the adverse effects of 3D contents, from the perspective of human factor, on the imbalance of visual accommodation and convergence, the present study is expected to broaden the applicable scope of 3D contents by utilizing the visual benefit of 3D contents for vision training.

  4. Integration Of 3D Geographic Information System (GIS) For Effective Waste Management Practice

    SciTech Connect

    Rood, G.J.; Hecox, G.R.

    2006-07-01

    Soil remediation in response to the presence of residual radioactivity resulting from past MED/AEC activities is currently in progress under the Formerly Utilized Sites Remedial Action Program near the St. Louis, MO airport. During GY05, approximately 92,000 cubic meters (120,000 cubic yards) of radioactive soil was excavated, packaged and transported via rail for disposal at U.S. Ecology or Envirocare of Utah, LLC. To facilitate the management of excavation/transportation/disposal activities, a 3D GIS was developed for the site that was used to estimate the in-situ radionuclide activities, activities in excavation block areas, and shipping activities using a sum-of ratio (SOR) method for combining various radionuclide compounds into applicable transportation and disposal SOR values. The 3D GIS was developed starting with the SOR values for the approximately 900 samples from 90 borings. These values were processed into a three-dimensional (3D) point grid using kriging with nominal grid spacing of 1.5 by 1.5 meter horizontal by 0.3 meter vertical. The final grid, clipped to the area and soil interval above the planned base of excavation, consisted of 210,000 individual points. Standard GIS volumetric and spatial join procedures were used to calculate the volume of soil represented by each grid point, the base of excavation, depth below ground surface, elevation, surface elevation and SOR values for each point in the final grid. To create the maps needed for management, the point grid results were spatially joined to each excavation area in 0.9 meter (3 foot) depth intervals and the average SOR and total volumes were calculations. The final maps were color-coded for easy identification of areas above the specific transportation or disposal criteria. (authors)

  5. Sedimentary basin effects in Seattle, Washington: Ground-motion observations and 3D simulations

    USGS Publications Warehouse

    Frankel, Arthur; Stephenson, William; Carver, David

    2009-01-01

    Seismograms of local earthquakes recorded in Seattle exhibit surface waves in the Seattle basin and basin-edge focusing of S waves. Spectral ratios of Swaves and later arrivals at 1 Hz for stiff-soil sites in the Seattle basin show a dependence on the direction to the earthquake, with earthquakes to the south and southwest producing higher average amplification. Earthquakes to the southwest typically produce larger basin surface waves relative to S waves than earthquakes to the north and northwest, probably because of the velocity contrast across the Seattle fault along the southern margin of the Seattle basin. S to P conversions are observed for some events and are likely converted at the bottom of the Seattle basin. We model five earthquakes, including the M 6.8 Nisqually earthquake, using 3D finite-difference simulations accurate up to 1 Hz. The simulations reproduce the observed dependence of amplification on the direction to the earthquake. The simulations generally match the timing and character of basin surface waves observed for many events. The 3D simulation for the Nisqually earth-quake produces focusing of S waves along the southern margin of the Seattle basin near the area in west Seattle that experienced increased chimney damage from the earthquake, similar to the results of the higher-frequency 2D simulation reported by Stephenson et al. (2006). Waveforms from the 3D simulations show reasonable agreement with the data at low frequencies (0.2-0.4 Hz) for the Nisqually earthquake and an M 4.8 deep earthquake west of Seattle.

  6. 3-D Hybrid Simulation of Quasi-Parallel Bow Shock and Its Effects on the Magnetosphere

    SciTech Connect

    Lin, Y.; Wang, X.Y.

    2005-08-01

    A three-dimensional (3-D) global-scale hybrid simulation is carried out for the structure of the quasi-parallel bow shock, in particular the foreshock waves and pressure pulses. The wave evolution and interaction with the dayside magnetosphere are discussed. It is shown that diamagnetic cavities are generated in the turbulent foreshock due to the ion beam plasma interaction, and these compressional pulses lead to strong surface perturbations at the magnetopause and Alfven waves/field line resonance in the magnetosphere.

  7. 3-D Storybook: Effects on Surgical Knowledge and Anxiety Among Four- to Six-Year-Old Surgical Patients.

    PubMed

    Macindo, John Rey B; Macabuag, Katherine R; Macadangdang, Carlo Miguel P; Macaranas, Margaux Valerie S; Macarilay, Marianne Jezelle Jem T; Madriñan, Natasha Nikki M; Villarama, Rouena S

    2015-07-01

    Inadequate surgical knowledge potentiates anxiety; however, no methodology simultaneously addresses anxiety and surgical knowledge. Our quasi-experimental study determined the effectiveness of a three-dimensional (3-D) storybook in increasing surgical knowledge and decreasing anxiety among young children scheduled for planned or required major surgeries. We studied 20 randomly assigned participants who received either the 3-D storybook or traditional health teaching. A presurgical knowledge questionnaire and modified Yale Preoperative Anxiety Scale assessed surgical knowledge and anxiety. Data were analyzed with one-way and repeated-measures multivariate analysis of variance. Results showed that both groups had higher knowledge scores (F = 8.94; P = .008) and lower anxiety scores (F = 5.13; P = .036) after the intervention. The children who received information from the 3-D storybook exhibited a significantly higher posttest knowledge score (F = 11.71; P = .003) and lower anxiety score (F = 10.05; P = .005) than the traditionally educated group of children. The 3-D storybook effectively increased surgical knowledge and decreased anxiety and could be used as an alternative method to prepare pediatric surgical patients.

  8. Effects of 2D and 3D Error Fields on the SAS Divertor Magnetic Topology

    NASA Astrophysics Data System (ADS)

    Trevisan, G. L.; Lao, L. L.; Strait, E. J.; Guo, H. Y.; Wu, W.; Evans, T. E.

    2016-10-01

    The successful design of plasma-facing components in fusion experiments is of paramount importance in both the operation of future reactors and in the modification of operating machines. Indeed, the Small Angle Slot (SAS) divertor concept, proposed for application on the DIII-D experiment, combines a small incident angle at the plasma strike point with a progressively opening slot, so as to better control heat flux and erosion in high-performance tokamak plasmas. Uncertainty quantification of the error fields expected around the striking point provides additional useful information in both the design and the modeling phases of the new divertor, in part due to the particular geometric requirement of the striking flux surfaces. The presented work involves both 2D and 3D magnetic error field analysis on the SAS strike point carried out using the EFIT code for 2D equilibrium reconstruction, V3POST for vacuum 3D computations and the OMFIT integrated modeling framework for data analysis. An uncertainty in the magnetic probes' signals is found to propagate non-linearly as an uncertainty in the striking point and angle, which can be quantified through statistical analysis to yield robust estimates. Work supported by contracts DE-FG02-95ER54309 and DE-FC02-04ER54698.

  9. 3D Equilibrium Effects Due to RMP Application on DIII-D

    SciTech Connect

    Lazerson, S.; Lazarus, E.; Hudson, S.; Pablant, N.; Gates, D.

    2012-06-20

    The mitigation and suppression of edge localized modes (ELMs) through application of resonant magnetic perturbations (RMPs) in Tokamak plasmas is a well documented phenomenon. Vacuum calculations suggest the formation of edge islands and stochastic regions when RMPs are applied to the axisymmetric equilibria. Self-consistent calculations of the plasma equilibrium with the VMEC and SPEC codes have been performed for an up-down symmetric shot in DIII-D. In these codes, a self-consistent calculation of the plasma response due to the RMP coils is calculated. The VMEC code globally enforces the constraints of ideal MHD; consequently, a continuously nested family of flux surfaces is enforced throughout the plasma domain. This approach necessarily precludes the observation of islands or field-line chaos. The SPEC code relaxes the constraints of ideal MHD locally, and allows for islands and field line chaos at or near the rational surfaces. Equilibria with finite pressure gradients are approximated by a set of discrete "ideal-interfaces" at the most irrational flux surfaces and where the strongest pressure gradients are observed. Both the VMEC and SPEC calculations are initialized from EFIT reconstructions of the plasma that are consistent with the experimental pressure and current profiles. A 3D reconstruction using the STELLOPT code, which fits VMEC equilibria to experimental measurements, has also been performed. Comparisons between the equilibria generated by the 3D codes and between STELLOPT and EFIT are presented.

  10. 3D Equilibrium Effects Due to RMP Application on DIII-D

    SciTech Connect

    S. Lazerson, E. Lazarus, S. Hudson, N. Pablant and D. Gates

    2012-06-20

    The mitigation and suppression of edge localized modes (ELMs) through application of resonant magnetic perturbations (RMPs) in Tokamak plasmas is a well documented phenomenon [1]. Vacuum calculations suggest the formation of edge islands and stochastic regions when RMPs are applied to the axisymmetric equilibria. Self-consistent calculations of the plasma equilibrium with the VMEC [2] and SPEC [3] codes have been performed for an up-down symmetric shot (142603) in DIII-D. In these codes, a self-consistent calculation of the plasma response due to the RMP coils is calculated. The VMEC code globally enforces the constraints of ideal MHD; consequently, a continuously nested family of flux surfaces is enforced throughout the plasma domain. This approach necessarily precludes the observation of islands or field-line chaos. The SPEC code relaxes the constraints of ideal MHD locally, and allows for islands and field line chaos at or near the rational surfaces. Equilibria with finite pressure gradients are approximated by a set of discrete "ideal-interfaces" at the most irrational flux surfaces and where the strongest pressure gradients are observed. Both the VMEC and SPEC calculations are initialized from EFIT reconstructions of the plasma that are consistent with the experimental pressure and current profiles. A 3D reconstruction using the STELLOPT code, which fits VMEC equilibria to experimental measurements, has also been performed. Comparisons between the equilibria generated by the 3D codes and between STELLOPT and EFIT are presented.

  11. 3D Mapping of plasma effective areas via detection of cancer cell damage induced by atmospheric pressure plasma jets

    NASA Astrophysics Data System (ADS)

    Han, Xu; Liu, Yueing; Stack, M. Sharon; Ptasinska, Sylwia

    2014-12-01

    In the present study, a nitrogen atmospheric pressure plasma jet (APPJ) was used for irradiation of oral cancer cells. Since cancer cells are very susceptible to plasma treatment, they can be used as a tool for detection of APPJ-effective areas, which extended much further than the visible part of the APPJ. An immunofluorescence assay was used for DNA damage identification, visualization and quantification. Thus, the effective damage area and damage level were determined and plotted as 3D images.

  12. Monte Carlo - Metropolis Investigations of Shape and Matrix Effects in 2D and 3D Spin-Crossover Nanoparticles

    NASA Astrophysics Data System (ADS)

    Guerroudj, Salim; Caballero, Rafael; De Zela, Francisco; Jureschi, Catalin; Linares, Jorge; Boukheddaden, Kamel

    2016-08-01

    The Ising like model, taking into account short-, long-range interaction as well as surface effects is used to investigate size and shape effects on the thermal behaviour of 2D and 3D spin crossover (SCO) nanoparticles embedded in a matrix. We analyze the role of the parametert, representing the ratio between the number of surface and volume molecules, on the unusual thermal hysteresis behaviour (appearance of the hysteresis and a re-entrance phase transition) at small scales.

  13. Effects of 3D Virtual Simulators in the Introductory Wind Energy Course: A Tool for Teaching Engineering Concepts

    SciTech Connect

    Do, Phuong T.; Moreland, John R.; Delgado, Catherine; Wilson, Kristina; Wang, Xiuling; Zhou, Chenn; Ice, Phil

    2013-01-01

    Our research provides an innovative solution for optimizing learning effectiveness and improving postsecondary education through the development of virtual simulators that can be easily used and integrated into existing wind energy curriculum. Two 3D virtual simulators are developed in our laboratory for use in an immersive 3D virtual reality (VR) system or for 3D display on a 2D screen. Our goal is to apply these prototypical simulators to train postsecondary students and professionals in wind energy education; and to offer experiential learning opportunities in 3D modeling, simulation, and visualization. The issue of transferring learned concepts to practical applications is a widespread problem in postsecondary education. Related to this issue is a critical demand to educate and train a generation of professionals for the wind energy industry. With initiatives such as the U.S. Department of Energy's “20% Wind Energy by 2030” outlining an exponential increase of wind energy capacity over the coming years, revolutionary educational reform is needed to meet the demand for education in the field of wind energy. These developments and implementation of Virtual Simulators and accompanying curriculum will propel national reforms, meeting the needs of the wind energy industrial movement and addressing broader educational issues that affect a number of disciplines.

  14. Effects of 3D Virtual Simulators in the Introductory Wind Energy Course: A Tool for Teaching Engineering Concepts

    DOE PAGES

    Do, Phuong T.; Moreland, John R.; Delgado, Catherine; ...

    2013-01-01

    Our research provides an innovative solution for optimizing learning effectiveness and improving postsecondary education through the development of virtual simulators that can be easily used and integrated into existing wind energy curriculum. Two 3D virtual simulators are developed in our laboratory for use in an immersive 3D virtual reality (VR) system or for 3D display on a 2D screen. Our goal is to apply these prototypical simulators to train postsecondary students and professionals in wind energy education; and to offer experiential learning opportunities in 3D modeling, simulation, and visualization. The issue of transferring learned concepts to practical applications is amore » widespread problem in postsecondary education. Related to this issue is a critical demand to educate and train a generation of professionals for the wind energy industry. With initiatives such as the U.S. Department of Energy's “20% Wind Energy by 2030” outlining an exponential increase of wind energy capacity over the coming years, revolutionary educational reform is needed to meet the demand for education in the field of wind energy. These developments and implementation of Virtual Simulators and accompanying curriculum will propel national reforms, meeting the needs of the wind energy industrial movement and addressing broader educational issues that affect a number of disciplines.« less

  15. Diffraction effects incorporated design of a parallax barrier for a high-density multi-view autostereoscopic 3D display.

    PubMed

    Yoon, Ki-Hyuk; Ju, Heongkyu; Kwon, Hyunkyung; Park, Inkyu; Kim, Sung-Kyu

    2016-02-22

    We present optical characteristics of view image provided by a high-density multi-view autostereoscopic 3D display (HD-MVA3D) with a parallax barrier (PB). Diffraction effects that become of great importance in such a display system that uses a PB, are considered in an one-dimensional model of the 3D display, in which the numerical simulation of light from display panel pixels through PB slits to viewing zone is performed. The simulation results are then compared to the corresponding experimental measurements with discussion. We demonstrate that, as a main parameter for view image quality evaluation, the Fresnel number can be used to determine the PB slit aperture for the best performance of the display system. It is revealed that a set of the display parameters, which gives the Fresnel number of ∼ 0.7 offers maximized brightness of the view images while that corresponding to the Fresnel number of 0.4 ∼ 0.5 offers minimized image crosstalk. The compromise between the brightness and crosstalk enables optimization of the relative magnitude of the brightness to the crosstalk and lead to the choice of display parameter set for the HD-MVA3D with a PB, which satisfies the condition where the Fresnel number lies between 0.4 and 0.7.

  16. Influence of 3D Radiative Effects on Satellite Retrievals of Cloud Properties

    NASA Technical Reports Server (NTRS)

    Varnai, Tamas; Marshak, Alexander; Einaudi, Franco (Technical Monitor)

    2001-01-01

    When cloud properties are retrieved from satellite observations, the calculations apply 1D theory to the 3D world: they only consider vertical structures and ignore horizontal cloud variability. This presentation discusses how big the resulting errors can be in the operational retrievals of cloud optical thickness. A new technique was developed to estimate the magnitude of potential errors by analyzing the spatial patterns of visible and infrared images. The proposed technique was used to set error bars for optical depths retrieved from new MODIS measurements. Initial results indicate that the 1 km resolution retrievals are subject to abundant uncertainties. Averaging over 50 by 50 km areas reduces the errors, but does not remove them completely; even in the relatively simple case of high sun (30 degree zenith angle), about a fifth of the examined areas had biases larger than ten percent. As expected, errors increase substantially for more oblique illumination.

  17. Investigation of gravitational effects in pulse tube cryocoolers using 3-D CFD

    NASA Astrophysics Data System (ADS)

    Mulcahey, T. I.; Conrad, T. J.; Ghiaasiaan, S. M.; Pathak, M. G.

    2014-01-01

    Stirling-type pulse tube cryocoolers (PTC) are often selected for cryogenic cooling applications for their robustness and mechanical simplicity, having no moving parts at the cold end of the cooler. Originally designed for space applications, increased terrestrial use in tactical applications as well as ground testing of space systems has revealed that some PTCs exhibit sensitivity to gravitational orientation, often losing significant cooling performance unless situated with the cold end pointing downward. Previous investigations have indicated that some coolers exhibit sensitivity while others do not; however, a reliable method of predicting the level of sensitivity during the design process has not been developed. We have utilized 3-D computational fluid dynamics (CFD) to predict the percent of cooling capacity lost as a result of off-axis operation. The computational model has been validated experimentally on a number of coolers to enhance confidence in the method used.

  18. Thermomechanical effects on permeability for a 3-D model of YM rock

    SciTech Connect

    Berge, P A; Blair, S C; Wang, H F

    1999-01-12

    The authors estimate how thermomechanical processes affect the spatial variability of fracture permeability for a 3-D model representing Topopah Spring tuff at the nuclear-waste repository horizon in Yucca Mountain, Nevada. Using a finite-difference code, they compute thermal stress changes. They evaluate possible permeability enhancement resulting from shear slip along various mapped fracture sets after 50 years of heating, for rock in the near-field environment of the proposed repository. The results indicate permeability enhancement of a factor of 2 for regions about 10 to 30 m above drifts, for north-south striking vertical fractures. Shear slip and permeability increases of a factor of 4 can occur in regions just above drifts, for east-west striking vertical fractures. Information on how permeability may change over the lifetime of a geologic repository is important to the prediction and evaluation of repository performance.

  19. Electrical Conductivity Beneath the Andean Back-arc in Argentina Near 36.5°S: Creation of Minimum Structure 2D Model Across EW Transect Based on Significantly 3D Data

    NASA Astrophysics Data System (ADS)

    Burd, A.; Booker, J.; Favetto, A.; Pomposiello, M.; Giordanengo, G.; Larsen, J. C.

    2006-12-01

    S. Mendoza Province, south of the Nazca flat slab, has widespread recent basaltic volcanism, but no historic activity. Over the last 1 MY, the basalt has evolved from having a slab signature to OIB. In early 2005, we collected 18 MT sites from 67 to 70°W along 36.7°S, near the large caldera Payún Matrú. Significantly 3D data cause difficulty identifying regional strike and performing minimum structure 2D inversions. Use of phase tensors and induction vectors allow identification of possible regional strikes. Various starting models for the minimum structure inversion allow comparison of effect of different regional strikes on the resulting electrical conductivity models. Preliminary analysis of a piecewise-2D region at the center of the profile suggests the west end of the profile to contain lower crustal to upper mantle conductivity which decreases and deepens to the east.

  20. A radiobiological analysis of the effect of 3D versus 4D image-based planning in lung cancer radiotherapy.

    PubMed

    Roland, Teboh; Mavroidis, Panayiotis; Gutierrez, Alonso; Goytia, Virginia; Papanikolaou, Niko

    2009-09-21

    Dose distributions generated on a static anatomy may differ significantly from those delivered to temporally varying anatomy such as for abdominal and thoracic tumors, due largely in part to the unavoidable organ motion and deformation effects stemming from respiration. In this work, the degree of such variation for three treatment techniques, namely static conventional, gating and target tracking radiotherapy, was investigated. The actual delivered dose was approximated by planning all the phases of a 4DCT image set. Data from six (n = 6) previously treated lung cancer patients were used for this study with tumor motion ranging from 2 to 10 mm. Complete radiobiological analyses were performed to assess the clinical significance of the observed discrepancies between the 3D and 4DCT image-based dose distributions. Using the complication-free tumor control probability (P+) objective, we observed small differences in P+ between the 3D and 4DCT image-based plans (<2.0% difference on average) for the gating and static conventional regimens and higher differences in P+ (4.0% on average) for the tracking regimen. Furthermore, we observed, as a general trend, that the 3D plan underestimated the P+ values. While it is not possible to draw any general conclusions from a small patient cohort, our results suggest that there exists a patient population in which 4D planning does not provide any additional benefits beyond that afforded by 3D planning for static conventional or gated radiotherapy. This statement is consistent with previous studies based on physical dosimetric evaluations only. The higher differences observed with the tracking technique suggest that individual patient plans should be evaluated on a case-by-case basis to assess if 3D or 4D imaging is appropriate for the tracking technique.

  1. Effect of magnetism on the solubility of 3 d elements in BCC iron: Results of first-principle investigations

    NASA Astrophysics Data System (ADS)

    Gorbatov, O. I.; Okatov, S. V.; Gornostyrev, Yu. N.; Korzhavyi, P. A.; Ruban, A. V.

    2013-08-01

    The methods of quantum-mechanical simulation have been used to study alloys of bcc iron with 3 d transition metals in the ferromagnetic and paramagnetic states. It has been shown that the main factor that determines the solubility of the 3 d elements is their electronic structure. The energy of the solution, mixing, and effective interatomic interactions vary regularly depending on the position of the element in the Periodic Table and on the magnetic state of the matrix. In some cases, depending on the magnetic state, changes in these quantities lead to the violation of the Hume-Rothery rules that determine the solubility of substitutional elements in alloys. The results obtained help us to understand the microscopic mechanisms that determine the solubility of alloying elements and their effect on the phase stability and structural state of steels.

  2. Fast 3D Net Expeditions: Tools for Effective Scientific Collaboration on the World Wide Web

    NASA Technical Reports Server (NTRS)

    Watson, Val; Chancellor, Marisa K. (Technical Monitor)

    1996-01-01

    Two new technologies, the FASTexpedition and Remote FAST, have been developed that provide remote, 3D (three dimensional), high resolution, dynamic, interactive viewing of scientific data. The FASTexpedition permits one to access scientific data from the World Wide Web, take guided expeditions through the data, and continue with self controlled expeditions through the data. Remote FAST permits collaborators at remote sites to simultaneously view an analysis of scientific data being controlled by one of the collaborators. Control can be transferred between sites. These technologies are now being used for remote collaboration in joint university, industry, and NASA projects. Also, NASA Ames Research Center has initiated a project to make scientific data and guided expeditions through the data available as FASTexpeditions on the World Wide Web for educational purposes. Previously, remote visualization of dynamic data was done using video format (transmitting pixel information) such as video conferencing or MPEG (Motion Picture Expert Group) movies on the Internet. The concept for this new technology is to send the raw data (e.g., grids, vectors, and scalars) along with viewing scripts over the Internet and have the pixels generated by a visualization tool running on the viewers local workstation. The visualization tool that is currently used is FAST (Flow Analysis Software Toolkit). The advantages of this new technology over using video format are: (1) The visual is much higher in resolution (1280x1024 pixels with 24 bits of color) than typical video format transmitted over the network. (2) The form of the visualization can be controlled interactively (because the viewer is interactively controlling the visualization tool running on his workstation). (3) A rich variety of guided expeditions through the data can be included easily. (4) A capability is provided for other sites to see a visual analysis of one site as the analysis is interactively performed. Control of

  3. Effect of microgravity simulation using 3D clinostat on cavendish banana (Musa acuminata AAA Group) ripening process

    NASA Astrophysics Data System (ADS)

    Dwivany, Fenny Martha; Esyanti, Rizkita R.; Prapaisie, Adeline; Puspa Kirana, Listya; Latief, Chunaeni; Ginaldi, Ari

    2016-11-01

    The objective of the research was to determine the effect of microgravity simulation by 3D clinostat on Cavendish banana (Musa acuminata AAA group) ripening process. In this study, physical, physiological changes as well as genes expression were analysed. The result showed that in microgravity simulation condition ripening process in banana was delayed and the MaACOl, MaACSl and MaACS5 gene expression were affected.

  4. Design and testing of indigenous cost effective three dimensional radiation field analyser (3D RFA).

    PubMed

    Ganesh, K M; Pichandi, A; Nehru, R M; Ravikumar, M

    2014-06-01

    The aim of the study is to design and validate an indigenous three dimensional Radiation Field Analyser (3D RFA). The feed system made for X, Y and Z axis movements is of lead screw with deep ball bearing mechanism made up of stain less steel driven by stepper motors with accuracy less than 0.5 mm. The telescopic column lifting unit was designed using linear actuation technology for lifting the water phantom. The acrylic phantom with dimensions of 800 x 750 x 570 mm was made with thickness of 15 mm. The software was developed in visual basic programming language, classified into two types, viz. beam analyzer software and beam acquisition software. The premeasurement checks were performed as per TG 106 recommendations. The physical parameters of photon PDDs such as Dmax, D10, D20 and Quality Index (QI), and the electron PDDs such as R50, Rp, E0, Epo and X-ray contamination values can be obtained instantaneously by using the developed RFA system. Also the results for profile data such as field size, central axis deviation, penumbra, flatness and symmetry calculated according to various protocols can be obtained for both photon and electron beams. The result of PDDs for photon beams were compared with BJR25 supplement values and the profile data were compared with TG 40 recommendation. The results were in agreement with standard protocols.

  5. Acute effects of delayed reperfusion following myocardial infarction: a 3D x-ray imaging analysis

    NASA Astrophysics Data System (ADS)

    Simari, Robert D.; Bell, M. R.; Pao, Y. C.; Gersh, B. J.; Ritman, Erik L.

    1996-04-01

    Clinical and experimental data suggest that delayed reperfusion of the infarct related artery may limit infarct expansion without increasing myocardial salvage. In order to assess the potential mechanisms involved, an acute closed chest canine model of myocardial infarction and delayed reperfusion was studied. Nineteen dogs underwent 3D computed tomography in the Dynamic Spatial Reconstructor (a fast, volume imaging, CT scanner) at baseline and three and four hours later to estimate left ventricular chamber volumes, global distensibility and regional myocardial stiffness. A control group was scanned without intervention. An occlusion group underwent four hours of coronary artery occlusion. A reperfusion group underwent three hours of coronary artery occlusion followed by one hour of reperfusion. Similar infarct sizes were seen in the occlusion and reperfusion groups. Globally reperfusion was associated with increased left ventricular end diastolic pressure and prolongation of global relaxation. Regionally reperfusion was associated with increased myocardial stiffness, intramyocardial blood volume and wall thickness within the infarct zone relative to the not reperfused myocardium.

  6. Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model

    PubMed Central

    Khoh-Reiter, Su; Jessen, Bart A

    2009-01-01

    Background Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic solution using an organotypic 3-dimensional (3-D) corneal epithelial model and to determine the effects of latanoprost ophthalmic solution and its BAC-containing vehicle on corneal thickness in a monkey model. Methods The cytotoxicity of commercially available BAC-containing ophthalmic formulations of latanoprost (0.02% BAC) and olopatadine (0.01% BAC) was compared to that of BAC-free travoprost and saline in a corneal organotypic 3-D model using incubation times of 10 and 25 minutes. To compare the extent of differentiation of 3-D corneal cultures to monolayer transformed human corneal epithelial (HCE-T) cell cultures, expression levels (mRNA and protein) of the corneal markers epidermal growth factor receptor, transglutaminase 1 and involucrin were quantified. Finally, latanoprost ophthalmic solution or its vehicle was administered at suprapharmacologic doses (two 30 μL drops twice daily in 1 eye for 1 year) in monkey eyes, and corneal pachymetry was performed at baseline and at weeks 4, 13, 26 and 52. Results In the 3-D corneal epithelial culture assays, there were no significant differences in cytotoxicity between the BAC-containing latanoprost and olopatadine ophthalmic solutions and BAC-free travoprost ophthalmic solution at either the 10- or 25-minute time points. The 3-D cultures expressed higher levels of corneal epithelial markers than the HCE-T monolayers, indicating a greater degree of differentiation. There were no significant differences between the corneal thickness of monkey eyes treated with latanoprost ophthalmic solution or its vehicle (both containing 0.02% BAC) and untreated eyes. Conclusion The lack of cytotoxicity demonstrated in 3-D corneal cultures and in monkey studies suggests that the levels of BAC contained in ophthalmic

  7. Effects of Surface Morphology on the 3D Topological Insulator Samarium Hexaboride

    NASA Astrophysics Data System (ADS)

    Wolgast, Steven; Eo, Yun Suk; Kurdak, Cagliyan; Kim, Dae-Jeong; Fisk, Zachary

    2015-03-01

    The recent verification of a topologically-protected surface state in SmB6 at low temperatures has led to several transport studies of the surface states. This task is complicated because current can flow on all surfaces of a topological insulator, each of which can have different transport characteristics. Our own measurements using a Corbino disc geometry overcome this difficulty, limiting the conduction to individual surfaces. However, the sheet conductivities of our samples counter-intuitively decrease with finer surface polishing. We therefore investigate surface and sub-surface morphology as a factor affecting the surface conductivity. Specifically, surface cracks may themselves harbor surface states and contribute to the total electrical conduction, yielding a higher measured sheet conductivity than that of a flat surface. This situation may contribute to the (sometimes unphysically) large surface conductivities already observed in SmB6. Performed in part at the Lurie Nanofabrication Facility and the Electron Microbeam Analysis Laboratory. Funded by NSF Grant #DMR-1006500 and DMR-1441965. Thanks to Gang Li and Fan Yu for optical imaging.

  8. Effect of space balance 3D training using visual feedback on balance and mobility in acute stroke patients

    PubMed Central

    Ko, YoungJun; Ha, HyunGeun; Bae, Young-Hyeon; Lee, WanHee

    2015-01-01

    [Purpose] The purpose of the study was to determine the effects of balance training with Space Balance 3D, which is a computerized measurement and visual feedback balance assessment system, on balance and mobility in acute stroke patients. [Subjects and Methods] This was a randomized controlled trial in which 52 subjects were assigned randomly into either an experimental group or a control group. The experimental group, which contained 26 subjects, received balance training with a Space Balance 3D exercise program and conventional physical therapy interventions 5 times per week during 3 weeks. Outcome measures were examined before and after the 3-week interventions using the Berg Balance Scale (BBS), Timed Up and Go (TUG) test, and Postural Assessment Scale for Stroke Patients (PASS). The data were analyzed by a two-way repeated measures ANOVA using SPSS 19.0. [Results] The results revealed a nonsignificant interaction effect between group and time period for both groups before and after the interventions in the BBS score, TUG score, and PASS score. In addition, the experimental group showed more improvement than the control group in the BBS, TUG and PASS scores, but the differences were not significant. In the comparisons within the groups by time, both groups showed significant improvement in BBS, TUG, and PASS scores. [Conclusion] The Space Balance 3D training with conventional physical therapy intervention is recommended for improvement of balance and mobility in acute stroke patients. PMID:26157270

  9. CFD Code Calibration and Inlet-Fairing Effects On a 3D Hypersonic Powered-Simulation Model

    NASA Technical Reports Server (NTRS)

    Huebner, Lawrence D.; Tatum, Kenneth E.

    1993-01-01

    A three-dimensional (3D) computational study has been performed addressing issues related to the wind tunnel testing of a hypersonic powered-simulation model. The study consisted of three objectives. The first objective was to calibrate a state-of-the-art computational fluid dynamics (CFD) code in its ability to predict hypersonic powered-simulation flows by comparing CFD solutions with experimental surface pressure data. Aftbody lower surface pressures were well predicted, but lower surface wing pressures were less accurately predicted. The second objective was to determine the 3D effects on the aftbody created by fairing over the inlet; this was accomplished by comparing the CFD solutions of two closed-inlet powered configurations with a flowing- inlet powered configuration. Although results at four freestream Mach numbers indicate that the exhaust plume tends to isolate the aftbody surface from most forebody flow- field differences, a smooth inlet fairing provides the least aftbody force and moment variation compared to a flowing inlet. The final objective was to predict and understand the 3D characteristics of exhaust plume development at selected points on a representative flight path. Results showed a dramatic effect of plume expansion onto the wings as the freestream Mach number and corresponding nozzle pressure ratio are increased.

  10. 3D digital image correlation investigation of PLC effect in a new Ni-Co base superalloy

    NASA Astrophysics Data System (ADS)

    Gao, Y.; Fu, S. H.; Cheng, T.; Huo, X.; Zhang, Q. C.

    2013-06-01

    Repeated plastic instability accompanying serrated yielding in stress-strain curves and localization of deformation is observed during plastic deformation of many metallic alloys when tensile specimens are deformed under certain experimental conditions of temperature, strain rate, and pre-deformation. This phenomenon is referred to as the Portevin- Le Chatelier (PLC) effect. TMW alloy, a newly developed Ni-Co base superalloy for aircraft engine application, also exhibit PLC effect during tensile test at temperatures ranging from 300 ° to 600 °, which are also the temperature range for engine working. In this paper, a 3D digital image correlation (3D DIC) measurement system was established to observe the localization of deformation (PLC band) in a tensile test performed on TMW alloy specimen at temperature of 400 °. The 3D DIC system, with displacement measurement accuracy up to 0.01 pixels and strain measurement accuracy up to 100 μɛ, has a high performance in displacement field calculation with more than 10000 points every second on a 3.1G Hz CPU computer. The test result shows that, the PLC bands are inclined at an angle of about 60° to the tensile axis. Unlike tensile test performed on aluminums alloy, the widths of PLC bands of TMW alloy specimen, ranging from 4 mm to 4.5 mm, are much greater than the specimen thickness (0.25 mm).

  11. A 3D Faraday Shield for Interdigitated Dielectrometry Sensors and Its Effect on Capacitance.

    PubMed

    Risos, Alex; Long, Nicholas; Hunze, Arvid; Gouws, Gideon

    2016-12-31

    Interdigitated dielectrometry sensors (IDS) are capacitive sensors investigated to precisely measure the relative permittivity ( ϵ r ) of insulating liquids. Such liquids used in the power industry exhibit a change in ϵ r as they degrade. The IDS ability to measure ϵ r in-situ can potentially reduce maintenance, increase grid stability and improve safety. Noise from external electric field sources is a prominent issue with IDS. This paper investigates the novelty of applying a Faraday cage onto an IDS as a 3D shield to reduce this noise. This alters the spatially distributed electric field of an IDS affecting its sensing properties. Therefore, dependency of the sensor's signal with the distance to a shield above the IDS electrodes has been investigated experimentally and theoretically via a Green's function calculation and FEM. A criteria of the shield's distance s = s 0 has been defined as the distance which gives a capacitance for the IDS equal to 1 - e - 2 = 86.5 % of its unshielded value. Theoretical calculations using a simplified geometry gave a constant value for s 0 / λ = 1.65, where λ is the IDS wavelength. In the experiment, values for s 0 were found to be lower than predicted as from theory and the ratio s 0 / λ variable. This was analyzed in detail and it was found to be resulting from the specific spatial structure of the IDS. A subsequent measurement of a common insulating liquid with a nearby noise source demonstrates a considerable reduction in the standard deviation of the relative permittivity from σ unshielded = ± 9.5% to σ shielded = ± 0.6%. The presented findings enhance our understanding of IDS in respect to the influence of a Faraday shield on the capacitance, parasitic capacitances of the IDS and external noise impact on the measurement of ϵ r .

  12. A 3D Faraday Shield for Interdigitated Dielectrometry Sensors and Its Effect on Capacitance

    PubMed Central

    Risos, Alex; Long, Nicholas; Hunze, Arvid; Gouws, Gideon

    2016-01-01

    Interdigitated dielectrometry sensors (IDS) are capacitive sensors investigated to precisely measure the relative permittivity (ϵr) of insulating liquids. Such liquids used in the power industry exhibit a change in ϵr as they degrade. The IDS ability to measure ϵr in-situ can potentially reduce maintenance, increase grid stability and improve safety. Noise from external electric field sources is a prominent issue with IDS. This paper investigates the novelty of applying a Faraday cage onto an IDS as a 3D shield to reduce this noise. This alters the spatially distributed electric field of an IDS affecting its sensing properties. Therefore, dependency of the sensor’s signal with the distance to a shield above the IDS electrodes has been investigated experimentally and theoretically via a Green’s function calculation and FEM. A criteria of the shield’s distance s = s0 has been defined as the distance which gives a capacitance for the IDS equal to 1 − e−2=86.5% of its unshielded value. Theoretical calculations using a simplified geometry gave a constant value for s0/λ = 1.65, where λ is the IDS wavelength. In the experiment, values for s0 were found to be lower than predicted as from theory and the ratio s0/λ variable. This was analyzed in detail and it was found to be resulting from the specific spatial structure of the IDS. A subsequent measurement of a common insulating liquid with a nearby noise source demonstrates a considerable reduction in the standard deviation of the relative permittivity from σunshielded=±9.5% to σshielded=±0.6%. The presented findings enhance our understanding of IDS in respect to the influence of a Faraday shield on the capacitance, parasitic capacitances of the IDS and external noise impact on the measurement of ϵr. PMID:28042868

  13. Effects of Novel 3D Antibiotic-Containing Electrospun Scaffolds on Dentin Discoloration

    PubMed Central

    Porter, Margaret Louise A.; Münchow, Eliseu A.; Albuquerque, Maria T. P.; Spolnik, Kenneth J.; Hara, Anderson T.; Bottino, Marco C.

    2016-01-01

    Introduction Although intracanal application of the triple antibiotic paste (TAP) may offer advantages (e.g., disinfection), this practice has been associated with significant drawbacks, including tooth discoloration. In this study, the color change of dentin was monitored during treatment with distinct TAP pastes and novel tubular-shaped three-dimensional (3D) electrospun scaffolds containing minocycline-MINO or doxycycline-DOX. Methods Two TAP pastes (TAPMINO–MINO, metronidazole/MET, and ciprofloxacin/CIP; and TAPDOX–DOX, MET, and CIP), four scaffold-based groups containing MINO or DOX, at distinct concentrations; one antibiotic-free scaffold (Scaffold); and one untreated group (Control) were investigated. Human canines were sectioned at the cemento-enamel junction (CEJ) and tubular-shaped scaffolds or paste were placed into the root canals and sealed. Color measurements (CIEL*a*b* parameters) were performed at baseline and after 1, 3, 7, 14, 21, and 28 days. Color changes were expressed as ΔE* values. In addition, scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) were also performed on the specimens after treatment. Data were analyzed using Repeated-measures ANOVA (alpha=0.05). Results All antibiotic-containing groups led to greater discoloration than the antibiotic-free groups. A severe discoloration occurred after 1 day. At the end of the experiment, antibiotic-treated samples exhibited crusts/agglomerates over the dentin surface, which totally or partially obliterated the dentinal tubules. The presence of MINO resulted in greater color change than DOX. Conclusion Scaffolds containing MINO or DOX produced similar color change to dentin when compared to their respective TAP systems, although DOX-related discoloration was less pronounced. PMID:26602451

  14. Effect of GIA models with 3D composite mantle viscosity on GRACE mass balance estimates for Antarctica

    NASA Astrophysics Data System (ADS)

    van der Wal, Wouter; Whitehouse, Pippa L.; Schrama, Ernst J. O.

    2015-03-01

    Seismic data indicate that there are large viscosity variations in the mantle beneath Antarctica. Consideration of such variations would affect predictions of models of Glacial Isostatic Adjustment (GIA), which are used to correct satellite measurements of ice mass change. However, most GIA models used for that purpose have assumed the mantle to be uniformly stratified in terms of viscosity. The goal of this study is to estimate the effect of lateral variations in viscosity on Antarctic mass balance estimates derived from the Gravity Recovery and Climate Experiment (GRACE) data. To this end, recently-developed global GIA models based on lateral variations in mantle temperature are tuned to fit constraints in the northern hemisphere and then compared to GPS-derived uplift rates in Antarctica. We find that these models can provide a better fit to GPS uplift rates in Antarctica than existing GIA models with a radially-varying (1D) rheology. When 3D viscosity models in combination with specific ice loading histories are used to correct GRACE measurements, mass loss in Antarctica is smaller than previously found for the same ice loading histories and their preferred 1D viscosity profiles. The variation in mass balance estimates arising from using different plausible realizations of 3D viscosity amounts to 20 Gt/yr for the ICE-5G ice model and 16 Gt/yr for the W12a ice model; these values are larger than the GRACE measurement error, but smaller than the variation arising from unknown ice history. While there exist 1D Earth models that can reproduce the total mass balance estimates derived using 3D Earth models, the spatial pattern of gravity rates can be significantly affected by 3D viscosity in a way that cannot be reproduced by GIA models with 1D viscosity. As an example, models with 1D viscosity always predict maximum gravity rates in the Ross Sea for the ICE-5G ice model, however, for one of the three preferred 3D models the maximum (for the same ice model) is found

  15. Effect of 3-D viscoelastic structure on post-seismic relaxation from the 2004 M = 9.2 Sumatra earthquake

    USGS Publications Warehouse

    Pollitz, F.; Banerjee, P.; Grijalva, K.; Nagarajan, B.; Burgmann, R.

    2008-01-01

    The 2004 M=9.2 Sumatra-Andaman earthquake profoundly altered the state of stress in a large volume surrounding the ???1400 km long rupture. Induced mantle flow fields and coupled surface deformation are sensitive to the 3-D rheology structure. To predict the post-seismic motions from this earthquake, relaxation of a 3-D spherical viscoelastic earth model is simulated using the theory of coupled normal modes. The quasi-static deformation basis set and solution on the 3-D model is constructed using: a spherically stratified viscoelastic earth model with a linear stress-strain relation; an aspherical perturbation in viscoelastic structure; a 'static'mode basis set consisting of Earth's spheroidal and toroidal free oscillations; a "viscoelastic" mode basis set; and interaction kernels that describe the coupling among viscoelastic and static modes. Application to the 2004 Sumatra-Andaman earthquake illustrates the profound modification of the post-seismic flow field at depth by a slab structure and similarly large effects on the near-field post-seismic deformation field at Earth's surface. Comparison with post-seismic GPS observations illustrates the extent to which viscoelastic relaxation contributes to the regional post-seismic deformation. ?? Journal compilation ?? 2008 RAS.

  16. From 2D to 3D--a New Dimension for Modelling the Effect of Natural Products on Human Tissue.

    PubMed

    Wrzesinski, Krzysztof; Fey, Stephen J

    2015-01-01

    Natural products, or their synthetic derivatives are a treasure trove to find potential candidates for novel drugs for human treatment. The selection of diamonds from the huge pile of worthless stone is a critical--and difficult--stage in the discovery pipeline. Of all the factors to be considered, perhaps the most important, is that the compound should have the desired effect on the tissue in vivo. Since it is not possible (or ethical) to test all compounds in vivo one must preselect using a surrogate assay system. While animal models have the advantage of being holistic and current 3D culture systems are reductionistic, they at least can be constructed from human cell types. In this review we will consider some of the evidence demonstrating that cells grown in 3D cultures have physiological performances that mimic functions seen in human tissues significantly better than cells grown using classical 2D culture systems. We will discuss advantages and disadvantages of these new culture technologies and highlight theoretical reasons for the differences. 3D cell culture technologies are more labour intensive than 2D culture systems and therefore their introduction is a trade-off between the value of obtaining data that is more relevant to the human condition against their through-put. It is already clear that future in vitro 3D systems will become more complex, using multiple cell types to more faithfully represent a particular tissue or even organ system. And one thing is sure - the diamonds are not easy to find!

  17. 3D vision system assessment

    NASA Astrophysics Data System (ADS)

    Pezzaniti, J. Larry; Edmondson, Richard; Vaden, Justin; Hyatt, Bryan; Chenault, David B.; Kingston, David; Geulen, Vanilynmae; Newell, Scott; Pettijohn, Brad

    2009-02-01

    In this paper, we report on the development of a 3D vision system consisting of a flat panel stereoscopic display and auto-converging stereo camera and an assessment of the system's use for robotic driving, manipulation, and surveillance operations. The 3D vision system was integrated onto a Talon Robot and Operator Control Unit (OCU) such that direct comparisons of the performance of a number of test subjects using 2D and 3D vision systems were possible. A number of representative scenarios were developed to determine which tasks benefited most from the added depth perception and to understand when the 3D vision system hindered understanding of the scene. Two tests were conducted at Fort Leonard Wood, MO with noncommissioned officers ranked Staff Sergeant and Sergeant First Class. The scenarios; the test planning, approach and protocols; the data analysis; and the resulting performance assessment of the 3D vision system are reported.

  18. 3D Printing of Graphene Aerogels.

    PubMed

    Zhang, Qiangqiang; Zhang, Feng; Medarametla, Sai Pradeep; Li, Hui; Zhou, Chi; Lin, Dong

    2016-04-06

    3D printing of a graphene aerogel with true 3D overhang structures is highlighted. The aerogel is fabricated by combining drop-on-demand 3D printing and freeze casting. The water-based GO ink is ejected and freeze-cast into designed 3D structures. The lightweight (<10 mg cm(-3) ) 3D printed graphene aerogel presents superelastic and high electrical conduction.

  19. Comparison of different approaches of estimating effective dose from reported exposure data in 3D imaging with interventional fluoroscopy systems

    NASA Astrophysics Data System (ADS)

    Svalkvist, Angelica; Hansson, Jonny; Bâth, Magnus

    2014-03-01

    Three-dimensional (3D) imaging with interventional fluoroscopy systems is today a common examination. The examination includes acquisition of two-dimensional projection images, used to reconstruct section images of the patient. The aim of the present study was to investigate the difference in resulting effective dose obtained using different levels of complexity in calculations of effective doses from these examinations. In the study the Siemens Artis Zeego interventional fluoroscopy system (Siemens Medical Solutions, Erlangen, Germany) was used. Images of anthropomorphic chest and pelvis phantoms were acquired. The exposure values obtained were used to calculate the resulting effective doses from the examinations, using the computer software PCXMC (STUK, Helsinki, Finland). The dose calculations were performed using three different methods: 1. using individual exposure values for each projection image, 2. using the mean tube voltage and the total DAP value, evenly distributed over the projection images, and 3. using the mean kV and the total DAP value, evenly distributed over smaller selection of projection images. The results revealed that the difference in resulting effective dose between the first two methods was smaller than 5%. When only a selection of projection images were used in the dose calculations the difference increased to over 10%. Given the uncertainties associated with the effective dose concept, the results indicate that dose calculations based on average exposure values distributed over a smaller selection of projection angles can provide reasonably accurate estimations of the radiation doses from 3D imaging using interventional fluoroscopy systems.

  20. Europeana and 3D

    NASA Astrophysics Data System (ADS)

    Pletinckx, D.

    2011-09-01

    The current 3D hype creates a lot of interest in 3D. People go to 3D movies, but are we ready to use 3D in our homes, in our offices, in our communication? Are we ready to deliver real 3D to a general public and use interactive 3D in a meaningful way to enjoy, learn, communicate? The CARARE project is realising this for the moment in the domain of monuments and archaeology, so that real 3D of archaeological sites and European monuments will be available to the general public by 2012. There are several aspects to this endeavour. First of all is the technical aspect of flawlessly delivering 3D content over all platforms and operating systems, without installing software. We have currently a working solution in PDF, but HTML5 will probably be the future. Secondly, there is still little knowledge on how to create 3D learning objects, 3D tourist information or 3D scholarly communication. We are still in a prototype phase when it comes to integrate 3D objects in physical or virtual museums. Nevertheless, Europeana has a tremendous potential as a multi-facetted virtual museum. Finally, 3D has a large potential to act as a hub of information, linking to related 2D imagery, texts, video, sound. We describe how to create such rich, explorable 3D objects that can be used intuitively by the generic Europeana user and what metadata is needed to support the semantic linking.

  1. Scoops3D: software to analyze 3D slope stability throughout a digital landscape

    USGS Publications Warehouse

    Reid, Mark E.; Christian, Sarah B.; Brien, Dianne L.; Henderson, Scott T.

    2015-01-01

    The computer program, Scoops3D, evaluates slope stability throughout a digital landscape represented by a digital elevation model (DEM). The program uses a three-dimensional (3D) method of columns approach to assess the stability of many (typically millions) potential landslides within a user-defined size range. For each potential landslide (or failure), Scoops3D assesses the stability of a rotational, spherical slip surface encompassing many DEM cells using a 3D version of either Bishop’s simplified method or the Ordinary (Fellenius) method of limit-equilibrium analysis. Scoops3D has several options for the user to systematically and efficiently search throughout an entire DEM, thereby incorporating the effects of complex surface topography. In a thorough search, each DEM cell is included in multiple potential failures, and Scoops3D records the lowest stability (factor of safety) for each DEM cell, as well as the size (volume or area) associated with each of these potential landslides. It also determines the least-stable potential failure for the entire DEM. The user has a variety of options for building a 3D domain, including layers or full 3D distributions of strength and pore-water pressures, simplistic earthquake loading, and unsaturated suction conditions. Results from Scoops3D can be readily incorporated into a geographic information system (GIS) or other visualization software. This manual includes information on the theoretical basis for the slope-stability analysis, requirements for constructing and searching a 3D domain, a detailed operational guide (including step-by-step instructions for using the graphical user interface [GUI] software, Scoops3D-i) and input/output file specifications, practical considerations for conducting an analysis, results of verification tests, and multiple examples illustrating the capabilities of Scoops3D. Easy-to-use software installation packages are available for the Windows or Macintosh operating systems; these packages

  2. Buoyancy effects on the 3D MHD stagnation-point flow of a Newtonian fluid

    NASA Astrophysics Data System (ADS)

    Borrelli, A.; Giantesio, G.; Patria, M. C.; Roşca, N. C.; Roşca, A. V.; Pop, I.

    2017-02-01

    This work examines the steady three-dimensional stagnation-point flow of an electrically conducting Newtonian fluid in the presence of a uniform external magnetic field H0 under the Oberbeck-Boussinesq approximation. We neglect the induced magnetic field and examine the three possible directions of H0 which coincide with the directions of the axes. In all cases it is shown that the governing nonlinear partial differential equations admit similarity solutions. We find that the flow has to satisfy an ordinary differential problem whose solution depends on the Hartmann number M, the buoyancy parameter λ and the Prandtl number Pr. The skin-friction components along the axes are computed and the stagnation-point is classified. The numerical integration shows the existence of dual solutions and the occurrence of the reverse flow for some values of the parameters.

  3. The effect of conjugating RGD into 3D alginate hydrogels on adipogenic differentiation of human adipose-derived stromal cells.

    PubMed

    Kang, Sun-Woong; Cha, Byung-Hyun; Park, Honghyun; Park, Kwang-Sook; Lee, Kuen Yong; Lee, Soo-Hong

    2011-05-12

    The effects of RGD peptide conjugation to alginate hydrogel on the adipogenic differentiation of ASCs was investigated. After 3 d of culture, RGD-modified alginate hydrogels significantly stimulated FAK and integrin α1 gene expressions and vinculin expression in ASCs. In addition, RGD-modified alginate hydrogels significantly enhanced the adipogenic differentiation of human ASCs to exhibit higher expression levels of oil red O staining and adipogenic genes compared to those of the control group (unmodified gels). These results suggest potential applications of RGD-modified alginate gels for adipose tissue regeneration.

  4. A 3D Model to Compute Lightning and HIRF Coupling Effects on Avionic Equipment of an Aircraft

    NASA Astrophysics Data System (ADS)

    Perrin, E.; Tristant, F.; Guiffaut, C.; Terrade, F.; Reineix, A.

    2012-05-01

    This paper describes the 3D FDTD model of an aircraft developed to compute the lightning and HIRF (High Intentity Radiated Fields) coupling effects on avionic equipment and all the wire harness associated. This virtual prototype aims at assisting the aircraft manufacturer during the lightning and HIRF certification processes. The model presented here permits to cover a frequency range from lightning spectrum to the low frequency HIRF domain, i.e. 0 to 100 MHz. Moreover, the entire aircraft, including the frame, the skin, the wire harness and the equipment are taken into account in only one model. Results obtained are compared to measurements on a real aircraft.

  5. Market study: 3-D eyetracker

    NASA Technical Reports Server (NTRS)

    1977-01-01

    A market study of a proposed version of a 3-D eyetracker for initial use at NASA's Ames Research Center was made. The commercialization potential of a simplified, less expensive 3-D eyetracker was ascertained. Primary focus on present and potential users of eyetrackers, as well as present and potential manufacturers has provided an effective means of analyzing the prospects for commercialization.

  6. The 3-D effects in the long-term solar wind speed rise observed by Voyager 2 in early 1994

    NASA Technical Reports Server (NTRS)

    Pizzo, V. J.; Paularena, K. I.; Richardson, J. D.; Lazarus, A. J.; Belcher, J. W.

    1995-01-01

    In early 1994, Voyager 2 at 42-43 AU near heliolatitude 10 deg S observed over a period of approximately 100 days a remarkable sequence of quasi-recurrent stream fronts, wherein the background (ambient) speed rose steadily from approximately 450 to approximately 550 km/s while the mean period of the streams decreased from the usual 25 days down to approximately 20 days. A qualitative explanation for this effect can be derived from IMP observations, which show that the amplitude of the stream structure at 1 AU increased monotonically in late 1993, concurrent with major secular evolution in the corona. The reduction in period, then, amounts to a doppler shift due to the progressive overtaking of successively faster streams in the sequence. Attempts to model this process quantitatively with 1-D dynamic simulations falter on three accounts: (1) the reduction in period is overestimated, (2) the simulation predicts many more fronts surviving to 43 AU than are observed by Voyager; (3) the density variations are much too large. It is argued that inclusion of the 3-D geometry in the simulation would resolve most all these shortcomings. Using a series of calculations executed with 1-D, 2-D, and 3-D MHD models of hypothetical tilted-dipole flows, we show that: (1) the radial propagation velocities of 3-D fronts are less than those of 1-D or 2-D fronts, owing to the tilt of (and increased shearing across) the interaction surfaces hence the overtaking rate of successive streams is reduced; (2) in a tilted-dipole geometry, the reverse fronts should largely disappear from the equatorial plane by 43 AU, effectively halving the number of fronts to be observed (see companion paper on predominance of forward fronts at Voyager); and (3) the density enhancements would be much smaller than predicted by a 1-D model.

  7. SU-E-T-353: Effects of Time and Temperature On a Potential Reusable 3D Dosimeter

    SciTech Connect

    Juang, T; Miles, D; Crockett, E; Adamovics, J; Oldham, M

    2015-06-15

    Purpose: Preliminary studies of a novel, optically-clearing PRESAGE 3D dosimeter formulation (Presage-RU) demonstrated potential reusability. This study investigates the effects of time and temperature on the accuracy and reusability of Presage-RU, and reports on progress toward developing a reusable 3D dosimeter. Methods: Presage-RU was cast as small volume samples (1×1×4.5cm). The effect of dose response sensitivity with reirradiation and time was evaluated by irradiating samples from 0–10Gy, measuring change in optical density (ΔOD), clearing at room temperature (RT) (5–7 days to fully clear), and then repeating for a total of 5 irradiations. Effects of heating on clearing rate were investigated by irradiating samples to 8Gy, then tracking measurements with samples held at RT, 35°C, and 45°C. Two cylindrical dosimeters (11cm diameter, 9.5cm length) were evaluated for dosimetric accuracy when stored at RT and −3°C prior to irradiation. Plans delivered were 2 overlapping AP fields (RT) and VMAT (-3°C). Results: Heating the dosimeters reduced the clearing half-life from 16.3h at RT to 5.8h (35°C) and 5.1h (45°C), but also increased background ΔOD by 1.7x (35°C) and 2.3x (45°C). Reductions in dose response were more closely linked to age than reirradiation, and storage at RT showed pronounced desensitization from dosimeter edges. These results suggest desensitization from oxygen diffusion. It should be noted that atmospheric diffusion into the dosimeter is not seen in standard, single-use PRESAGE, and is likely caused by differences in the Presage-RU polyurethane matrix. The dosimeter kept in cold storage, however, showed no evidence of desensitization and exhibited accuracy on par with standard PRESAGE with a 3%/3mm 3D gamma passing rate of 98.1%. Conclusions: Presage-RU is sensitive to storage temperatures and time, both of which affect oxygen diffusion and subsequent desensitization. Development shows promising progress with further formulation

  8. Representing 3-D cloud radiation effects in two-stream schemes: 2. Matrix formulation and broadband evaluation

    NASA Astrophysics Data System (ADS)

    Hogan, Robin J.; Schäfer, Sophia A. K.; Klinger, Carolin; Chiu, J. Christine; Mayer, Bernhard

    2016-07-01

    Estimating the impact of radiation transport through cloud sides on the global energy budget is hampered by the lack of a fast radiation scheme suitable for use in global atmospheric models that can represent these effects in both the shortwave and longwave. This two-part paper describes the development of such a scheme, which we refer to as the Speedy Algorithm for Radiative Transfer through Cloud Sides (SPARTACUS). The principle of the method is to add extra terms to the two-stream equations to represent lateral transport between clear and cloudy regions, which vary in proportion to the length of cloud edge as a function of height. The present paper describes a robust and accurate method for solving the coupled system of equations in both the shortwave and longwave in terms of matrix exponentials. This solver has been coupled to a correlated-k model for gas absorption. We then confirm the accuracy of SPARTACUS by performing broadband comparisons with fully 3-D radiation calculations by the Monte Carlo model "MYSTIC" for a cumulus cloud field, examining particularly the percentage change in cloud radiative effect (CRE) when 3-D effects are introduced. In the shortwave, SPARTACUS correctly captures this change to CRE, which varies with solar zenith angle between -25% and +120%. In the longwave, SPARTACUS captures well the increase in radiative cooling of the cloud, although it is only able to correctly simulate the 30% increase in surface CRE (around 4 W m-2) if an approximate correction is made for cloud clustering.

  9. Numerical and experimental study of the 3D effect on connecting arm of vertical axis tidal current turbine

    NASA Astrophysics Data System (ADS)

    Guo, Wei; Kang, Hai-gui; Chen, Bing; Xie, Yu; Wang, Yin

    2016-03-01

    Vertical axis tidal current turbine is a promising device to extract energy from ocean current. One of the important components of the turbine is the connecting arm, which can bring about a significant effect on the pressure distribution along the span of the turbine blade, herein we call it 3D effect. However, so far the effect is rarely reported in the research, moreover, in numerical simulation. In the present study, a 3D numerical model of the turbine with the connecting arm was developed by using FLUENT software compiling the UDF (User Defined Function) command. The simulation results show that the pressure distribution along the span of blade with the connecting arm model is significantly different from those without the connecting arm. To facilitate the validation of numerical model, the laboratory experiment has been carried out by using three different types of NACA aerofoil connecting arm and circle section connecting arm. And results show that the turbine with NACA0012 connecting arm has the best start-up performance which is 0.346 m/s and the peak point of power conversion coefficient is around 0.33. A further study has been performed and a conclusion is drawn that the aerofoil and thickness of connecting arm are the most important factors on the power conversion coefficient of the vertical axis tidal current turbine.

  10. 3D Effects on Minority Carrier Recombination in Homogeneous Silicon Wafers

    NASA Astrophysics Data System (ADS)

    Storgårds, J.; Väinölä, H.; Yli-Koski, M.; Sinkkonen, J.

    Calculation of three-dimensional recombination effects in homogeneous silicon wafers is performed. The current continuity equation for minority carriers with surface recombination boundary conditions is solved in cylindrical coordinates. The two most important three-dimensional recombination effects are discussed. Lateral diffusion of minority carriers gives rise to a characteristic decay inversely proportional to time. Shell surface recombination should be taken into account when measuring within the minority carrier diffusion length from the wafer edge. The discrepancy between the one-dimensional and the three-dimensional models is discussed.

  11. 3D effects of edge magnetic field configuration on divertor/scrape-off layer transport and optimization possibilities for a future reactor

    NASA Astrophysics Data System (ADS)

    Kobayashi, M.; Xu, Y.; Ida, K.; Corre, Y.; Feng, Y.; Schmitz, O.; Frerichs, H.; Tabares, F. L.; Evans, T. E.; Coenen, J. W.; Liang, Y.; Bader, A.; Itoh, K.; Yamada, H.; Ghendrih, Ph.; Ciraolo, G.; Tafalla, D.; Lopez-Fraguas, A.; Guo, H. Y.; Cui, Z. Y.; Reiter, D.; Asakura, N.; Wenzel, U.; Morita, S.; Ohno, N.; Peterson, B. J.; Masuzaki, S.

    2015-10-01

    This paper assesses the three-dimensional (3D) effects of the edge magnetic field structure on divertor/scrape-off layer transport, based on an inter-machine comparison of experimental data and on the recent progress of 3D edge transport simulation. The 3D effects are elucidated as a consequence of competition between transports parallel (\\parallel ) and perpendicular (\\bot ) to the magnetic field, in open field lines cut by divertor plates, or in magnetic islands. The competition has strong impacts on divertor functions, such as determination of the divertor density regime, impurity screening and detachment control. The effects of magnetic perturbation on the edge electric field and turbulent transport are also discussed. Parameterization to measure the 3D effects on the edge transport is attempted for the individual divertor functions. Based on the suggested key parameters, an operation domain of the 3D divertor configuration is discussed for future devices.

  12. Studies of Bystander Effects in 3-D Tissue Systems Using a Low-LET Microbeam

    SciTech Connect

    Brenner, David J.

    2009-07-17

    It is now accepted that biological effects may occur in cells that were not themselves traversed by ionizing radiation but are close to those that were. Little is known about the mechanism underlying such a bystander effect, although cell-to-cell communication is thought to be important. Previous work demonstrated a significant bystander effect for clonogenic survival and oncogenic transformation in C3H 10T(1/2) cells. Additional studies were undertaken to assess the importance of the degree of cell-to-cell contact at the time of irradiation on the magnitude of this bystander effect by varying the cell density. When 10% of cells were exposed to a range of 2-12 alpha particles, a significantly greater number of cells were inactivated when cells were irradiated at high density than at low density. In addition, the oncogenic transformation frequency was significantly higher in high-density cultures. These results suggest that when a cell is hit by radiation, the transmission of the bystander signal through cell-to-cell contact is an important mediator of the effect, implicating the involvement of intracellular communication through gap junctions. Additional studies to address the relationship between the bystander effect and the adaptive response were undertaken. A novel apparatus, where targeted and non-targeted cells were grown in close proximity, was used to investigate these. It was further examined whether a bystander effect or an adaptive response could be induced by a factor(s) present in the supernatants of cells exposed to a high or low dose of X-rays, respectively. When non-hit cells were co-cultured for 24 h with cells irradiated with 5 Gy alpha-particles, a significant increase in both cell killing and oncogenic transformation frequency was observed. If these cells were treated with 2 cGy X-rays 5 h before co-culture with irradiated cells, approximately 95% of the bystander effect was cancelled out. A 2.5-fold decrease in the oncogenic transformation

  13. Investigating the sonophoresis effect on the permeation of diclofenac sodium using 3D skin equivalent.

    PubMed

    Aldwaikat, Mai; Alarjah, Mohammed

    2015-01-01

    Ultrasound temporally increases skin permeability by altering stratum corneum SC function (sonophoresis). The objective of this study was to evaluate the effect of variable ultrasound conditions on the permeation of diclofenac sodium DS with range of physicochemical properties through EpiDerm™. Permeation studies were carried out in vitro using Franz diffusion cell. HPLC method was used for the determination of the concentration of diclofenac sodium in receiving compartment. Parameters like ultrasound frequency, application time, amplitude, and mode of sonication and distance of ultrasound horn from skin were investigated, and the conditions where the maximum enhancement rate obtained were determined. Application of ultrasound enhanced permeation of diclofenac sodium across EpiDerm™ by fivefolds. The most effective enhancing parameters were power sonication of 20kHz frequency, 20% amplitude at continuous mode for 5min.

  14. Effective declutter of complex flight displays using stereoptic 3-D cueing

    NASA Technical Reports Server (NTRS)

    Parrish, Russell V.; Williams, Steven P.; Nold, Dean E.

    1994-01-01

    The application of stereo technology to new, integrated pictorial display formats has been effective in situational awareness enhancements, and stereo has been postulated to be effective for the declutter of complex informational displays. This paper reports a full-factorial workstation experiment performed to verify the potential benefits of stereo cueing for the declutter function in a simulated tracking task. The experimental symbology was designed similar to that of a conventional flight director, although the format was an intentionally confused presentation that resulted in a very cluttered dynamic display. The subject's task was to use a hand controller to keep a tracking symbol, an 'X', on top of a target symbol, another X, which was being randomly driven. In the basic tracking task, both the target symbol and the tracking symbol were presented as red X's. The presence of color coding was used to provide some declutter, thus making the task more reasonable to perform. For this condition, the target symbol was coded red, and the tracking symbol was coded blue. Noise conditions, or additional clutter, were provided by the inclusion of randomly moving, differently colored X symbols. Stereo depth, which was hypothesized to declutter the display, was utilized by placing any noise in a plane in front of the display monitor, the tracking symbol at screen depth, and the target symbol behind the screen. The results from analyzing the performances of eight subjects revealed that the stereo presentation effectively offsets the cluttering effects of both the noise and the absence of color coding. The potential of stereo cueing to declutter complex informational displays has therefore been verified; this ability to declutter is an additional benefit from the application of stereoptic cueing to pictorial flight displays.

  15. Capturing atmospheric effects on 3D millimeter wave radar propagation patterns

    NASA Astrophysics Data System (ADS)

    Cook, Richard D.; Fiorino, Steven T.; Keefer, Kevin J.; Stringer, Jeremy

    2016-05-01

    Traditional radar propagation modeling is done using a path transmittance with little to no input for weather and atmospheric conditions. As radar advances into the millimeter wave (MMW) regime, atmospheric effects such as attenuation and refraction become more pronounced than at traditional radar wavelengths. The DoD High Energy Laser Joint Technology Offices High Energy Laser End-to-End Operational Simulation (HELEEOS) in combination with the Laser Environmental Effects Definition and Reference (LEEDR) code have shown great promise simulating atmospheric effects on laser propagation. Indeed, the LEEDR radiative transfer code has been validated in the UV through RF. Our research attempts to apply these models to characterize the far field radar pattern in three dimensions as a signal propagates from an antenna towards a point in space. Furthermore, we do so using realistic three dimensional atmospheric profiles. The results from these simulations are compared to those from traditional radar propagation software packages. In summary, a fast running method has been investigated which can be incorporated into computational models to enhance understanding and prediction of MMW propagation through various atmospheric and weather conditions.

  16. Surface-effect corrections for solar-like oscillations using 3D hydrodynamical simulations. I. Adiabatic oscillations

    NASA Astrophysics Data System (ADS)

    Sonoi, T.; Samadi, R.; Belkacem, K.; Ludwig, H.-G.; Caffau, E.; Mosser, B.

    2015-11-01

    Context. The CoRoT and Kepler space-borne missions have provided us with a wealth of high-quality observational data that allows for seismic inferences of stellar interiors. This requires the computation of precise and accurate theoretical frequencies, but imperfect modeling of the uppermost stellar layers introduces systematic errors. To overcome this problem, an empirical correction has been introduced by Kjeldsen et al. (2008, ApJ, 683, L175) and is now commonly used for seismic inferences. Nevertheless, we still lack a physical justification allowing for the quantification of the surface-effect corrections. Aims: Our aim is to constrain the surface-effect corrections across the Hertzsprung-Russell (HR) diagram using a set of 3D hydrodynamical simulations. Methods: We used a grid of these simulations computed with the CO5BOLD code to model the outer layers of solar-like stars. Upper layers of the corresponding 1D standard models were then replaced by the layers obtained from the horizontally averaged 3D models. The frequency differences between these patched models and the 1D standard models were then calculated using the adiabatic approximation and allowed us to constrain the Kjeldsen et al. power law, as well as a Lorentzian formulation. Results: We find that the surface effects on modal frequencies depend significantly on both the effective temperature and the surface gravity. We further provide the variation in the parameters related to the surface-effect corrections using their power law as well as a Lorentzian formulation. Scaling relations between these parameters and the elevation (related to the Mach number) is also provided. The Lorentzian formulation is shown to be more robust for the whole frequency spectrum, while the power law is not suitable for the frequency shifts in the frequency range above νmax. Finally, we show that, owing to turbulent pressure, the elevation of the uppermost layers modifies the location of the hydrogen ionization zone and

  17. Splinting effect on posterior implants under various loading modes: a 3D finite element analysis.

    PubMed

    Hauchard, Erwan; Fournier, Benjamin Philippe; Jacq, Romain; Bouton, Antoine; Pierrisnard, Laurent; Naveau, Adrien

    2011-09-01

    This three-dimensional finite element study compared stresses, intensities and displacements of three mandibular posterior implants restored with cemented crowns (two molars and a premolar in straight line), splinted versus non-splinted. Hundred newton occlusal loads were vertically or horizontally applied, either on one single crown or on all of them. Maximal stresses and implants displacements were higher under horizontal loading. Splinting major effects appeared under single horizontal load with a decrease in stresses (34-49%) and displacements (16-19%) of the loaded crown. Splinting seems more appropriate for implant-supported restorations submitted to frequent single horizontal or oblique loads than vertical ones.

  18. The effects of age and workload on 3D spatial attention in dual-task driving

    PubMed Central

    Pierce, Russell S.; Andersen, George J.

    2014-01-01

    In the present study we assessed whether the limits in visual-spatial attention associated with aging affect the spatial extent of attention in depth during driving performance. Drivers in the present study performed a car-following and light-detection task. To assess the extent of visual-spatial attention, we compared reaction times and accuracy to light change targets that varied in horizontal position and depth location. In addition, because workload has been identified as a factor that can change the horizontal and vertical extent of attention, we tested whether variability of the lead car speed influenced the extent of spatial attention for younger or older drivers. For younger drivers, reaction time (RT) to light-change targets varied as a function of distance and horizontal position. For older drivers RT varied only as a function of distance. There was a distance by horizontal position interaction for younger drivers but not for older drivers. Specifically, there was no effect of horizontal position at any given level of depth for older drivers. However, for younger drivers there was an effect of horizontal position for targets further in depth but not for targets nearer in depth. With regards to workload, we found no statistically reliable evidence that variability of the lead car speed had an effect on the spatial extent of attention for younger or older drivers. In a control experiment, we examined the effects of depth on light detection when the projected size and position of the targets was constant. Consistent with our previous results, we found that drivers’ reaction time to light-change targets varied as a function of distance even when 2D position and size were controlled. Given that depth is an important dimension in driving performance, an important issue for assessing driving safety is to consider the limits of attention in the depth dimension. Therefore, we suggest that future research should consider the importance of depth as a dimension of

  19. Effect of sitting, standing, and supine body positions on facial soft tissue: detailed 3D analysis.

    PubMed

    Ozsoy, U; Sekerci, R; Ogut, E

    2015-10-01

    Medical imaging techniques require various body positions. Gravity causes changes in the facial soft tissue and acts in different directions according to the position of the head during imaging. The aim of this study was to evaluate the effect of positional changes on the facial soft tissue. The faces of subjects were scanned in the standing, sitting, and supine body positions. Differences in the positions were compared using the root mean square (RMS), mean absolute deviation (MAD), and mean signed distance (MSD). The displacement of 15 midsagittal and 20 bilateral landmarks was evaluated. The RMS, MAD, and MSD values of the sitting-standing comparison were significantly lower than those of the sitting-supine and standing-supine comparisons. There were no significant differences between the sitting-supine and standing-supine comparisons. Sixteen out of 135 measurements (12%) of the midsagittal landmarks and 94 out of 180 (52%) measurements of the bilateral landmarks showed significant displacements among the body positions. These results demonstrate a significant change in the facial soft tissue caused by body position. Furthermore, these data show the different susceptibilities of the facial soft tissue landmarks to the effect of body position along the x, y, and z axes.

  20. Effects of photophoresis on the dust distribution in a 3D protoplanetary disc

    NASA Astrophysics Data System (ADS)

    Cuello, N.; Gonzalez, J.-F.; Pignatale, F. C.

    2016-05-01

    Photophoresis is a physical process based on momentum exchange between an illuminated dust particle and its gaseous environment. Its net effect in protoplanetary discs (PPD) is the outward transport of solid bodies from hot to cold regions. This process naturally leads to the formation of ring-shaped features where dust piles up. In this work, we study the dynamical effects of photophoresis in PPD by including the photophoretic force in the two-fluid (gas+dust) smoothed particle hydrodynamics (SPH) code developed by Barrière-Fouchet et al. (2005). We find that the conditions of pressure and temperature encountered in the inner regions of PPD result in important photophoretic forces, which dramatically affect the radial motion of solid bodies. Moreover, dust particles have different equilibrium locations in the disc depending on their size and their intrinsic density. The radial transport towards the outer parts of the disc is more efficient for silicates than for iron particles, which has important implications for meteoritic composition. Our results indicate that photophoresis must be taken into account in the inner regions of PPD to fully understand the dynamics and the evolution of the dust composition.

  1. 3-D simulations to investigate initial condition effects on the growth of Rayleigh-Taylor mixing

    SciTech Connect

    Andrews, Malcolm J

    2008-01-01

    The effect of initial conditions on the growth rate of turbulent Rayleigh-Taylor (RT) mixing has been studied using carefully formulated numerical simulations. An integrated large-eddy simulation (ILES) that uses a finite-volume technique was employed to solve the three-dimensional incompressible Euler equations with numerical dissipation. The initial conditions were chosen to test the dependence of the RT growth parameters ({alpha}{sub b}, {alpha}{sub s}) on variations in (a) the spectral bandwidth, (b) the spectral shape, and (c) discrete banded spectra. Our findings support the notion that the overall growth of the RT mixing is strongly dependent on initial conditions. Variation in spectral shapes and bandwidths are found to have a complex effect of the late time development of the RT mixing layer, and raise the question of whether we can design RT transition and turbulence based on our choice of initial conditions. In addition, our results provide a useful database for the initialization and development of closures describing RT transition and turbulence.

  2. The effects of surface gloss and roughness on color constancy for real 3-D objects.

    PubMed

    Granzier, Jeroen J M; Vergne, Romain; Gegenfurtner, Karl R

    2014-02-21

    Color constancy denotes the phenomenon that the appearance of an object remains fairly stable under changes in illumination and background color. Most of what we know about color constancy comes from experiments using flat, matte surfaces placed on a single plane under diffuse illumination simulated on a computer monitor. Here we investigate whether material properties (glossiness and roughness) have an effect on color constancy for real objects. Subjects matched the color and brightness of cylinders (painted red, green, or blue) illuminated by simulated daylight (D65) or by a reddish light with a Munsell color book illuminated by a tungsten lamp. The cylinders were either glossy or matte and either smooth or rough. The object was placed in front of a black background or a colored checkerboard. We found that color constancy was significantly higher for the glossy objects compared to the matte objects, and higher for the smooth objects compared to the rough objects. This was independent of the background. We conclude that material properties like glossiness and roughness can have significant effects on color constancy.

  3. Testing remote sensing on artificial observations: impact of drizzle and 3-D cloud structure on effective radius retrievals

    NASA Astrophysics Data System (ADS)

    Zinner, T.; Wind, G.; Platnick, S.; Ackerman, A. S.

    2010-10-01

    Remote sensing of cloud effective particle size with passive sensors like the Moderate Resolution Imaging Spectroradiometer (MODIS) is an important tool for cloud microphysical studies. As a measure of the radiatively relevant droplet size, effective radius can be retrieved with different combinations of visible through shortwave and midwave infrared channels. In practice, retrieved effective radii from these combinations can be quite different. This difference is perhaps indicative of different penetration depths and path lengths for the spectral reflectances used. In addition, operational liquid water cloud retrievals are based on the assumption of a relatively narrow distribution of droplet sizes; the role of larger precipitation particles in these distributions is neglected. Therefore, possible explanations for the discrepancy in some MODIS spectral size retrievals could include 3-D radiative transport effects, including sub-pixel cloud inhomogeneity, and/or the impact of drizzle formation. For three cloud cases the possible factors of influence are isolated and investigated in detail by the use of simulated cloud scenes and synthetic satellite data: marine boundary layer cloud scenes from large eddy simulations (LES) with detailed microphysics are combined with Monte Carlo radiative transfer calculations that explicitly account for the detailed droplet size distributions as well as 3-D radiative transfer to simulate MODIS observations. The operational MODIS optical thickness and effective radius retrieval algorithm is applied to these and the results are compared to the given LES microphysics. We investigate two types of marine cloud situations each with and without drizzle from LES simulations: (1) a typical daytime stratocumulus deck at two times in the diurnal cycle and (2) one scene with scattered cumulus. Only small impact of drizzle formation on the retrieved domain average and on the differences between the three effective radius retrievals is noticed

  4. Effects of inflow distortion profiles on fan tone noise calculated using a 3-D theory

    NASA Technical Reports Server (NTRS)

    Kobayashi, H.; Groeneweg, J. F.

    1979-01-01

    Calculations of the fan tone acoustic power and modal structure generated by complex distortions in axial inflow velocity are presented. The model used treats the motor as a rotating three-dimensional cascade and calculates the acoustic field from the distortion-produced dipole distribution on the blades including noncompact source effects. Radial and circumferential distortion shapes are synthesized from Fourier-Bessel components representing individual distortion modes. The relation between individual distortion modes and the generated acoustic modes is examined for particular distortion cases. Comparisons between theoretical and experimental results for distortions produced by wakes from upstream radial rods show that the analysis is a good predictor of acoustic power dependence on disturbance strength.

  5. 3-D structures of crack-tip dislocations and their shielding effect revealed by electron tomography.

    PubMed

    Tanaka, Masaki; Honda, Masaki; Sadamatsu, Sunao; Higashida, Kenji

    2010-08-01

    Three-dimensional structures of crack-tip dislocations in silicon crystals have been examined by combining scanning transmission electron microscopy and computed tomography. Cracks were introduced by a Vickers hardness tester at room temperature, and the sample was heated at 823 K for 1 h in order to introduce dislocations around the crack tips. Dislocation segments cut out from loops were observed around the crack tip, the three-dimensional structure of which was characterized by using by electron tomography. Their Burgers vectors including the sings were also determined by oscillating contrasts along dislocations. In order to investigate the effect of the dislocations on fracture behaviours, local stress intensity factor due to one dislocation was calculated, which indicates the dislocations observed were shielding type to increase fracture toughness.

  6. An experiment to study the effects of space flight cells of mesenchymal origin in the new model 3D-graft in vitro

    NASA Astrophysics Data System (ADS)

    Volova, Larissa

    One of the major health problems of the astronauts are disorders of the musculoskeletal system, which determines the relevance of studies of the effect of space flight factors on osteoblastic and hondroblastic cells in vitro. An experiment to study the viability and proliferative activity of cells of mesenchymal origin on culture: chondroblasts and dermal fibroblasts was performed on SC "BION -M" № 1 with scientific equipment " BIOKONT -B ." To study the effect of space flight conditions in vitro at the cellular level has developed a new model with 3D- graft as allogeneic demineralized spongiosa obtained on technology Lioplast ®. For space and simultaneous experiments in the laboratory of the Institute of Experimental Medicine and Biotechnology Samara State Medical University were obtained from the cell culture of hyaline cartilage and human skin, which have previously been grown, and then identified by morphological and immunohistochemical methods. In the experiment, they were seeded on the porous 3D- graft (controlled by means of scanning electron and confocal microscopy) and cultured in full growth medium. After completion of the flight of spacecraft "BION -M" № 1 conducted studies of biological objects using a scanning electron microscope (JEOL JSM-6390A Analysis Station, Japan), confocal microscopy and LDH - test. According to the results of the experiment revealed that after a 30- day flight of the cells not only retained vitality, but also during the flight actively proliferate, and their number has increased by almost 8 times. In synchronous experiment, all the cells died by this date. The experimentally confirmed the adequacy of the proposed model 3D- graft in studying the effect of space flight on the morphological and functional characteristics of cells in vitro.

  7. 3D Global Climate Modelling of the environmental effect of meteoritic impacts on Early Mars

    NASA Astrophysics Data System (ADS)

    Turbet, Martin; Forget, Francois; Gillmann, Cedric; Karatekin, Ozgur; Svetsov, Vladimir; Popova, Olga; Wallemacq, Quentin

    2016-10-01

    There are now robust evidences that liquid water flowed on ancient Mars: dry river beds and lakes, hydrated sedimentary minerals and high erosion rates. Climate models that consider only CO2/H2O as greenhouse gases have been unable yet to produce warm climates suitable for liquid water on Early Mars, given the lower solar luminosity at that time. It has been suggested that the warm conditions required to explain the formation of the 3.8 Gyrs old valley networks could have been transient and produced in response to the meteoritic impacts that occured during the contemporaneous Late Heavy Bombardment (LHB). This scenario is appealing because, in a predominately cold climate, the ice tends to accumulate preferentially in the regions where the rivers were sculpted ('Icy Highlands' scenario). This would be a very efficient mechanism of recharge of the valley network water sources between two impact-induced melting events.Using the LMD Global Climate Model (LMD-GCM) designed for flexible (from cold & dry to warm & wet) conditions, we explored the environmental effect of LHB impact events of various sizes on Early Mars. Our main result is that, whatever the initial impact-induced temperatures and water vapor content injected, warm climates cannot be stable and are in fact short-lived (lifetime of ~ 5 martian years/bar of H2O injected). Moreover, we will give preliminar estimates of the amount of rainfall/snowmelt that can be produced after impact events depending on their size, following three different approaches:1) For large impact events (Dimpactor < 50km, N ~ 40) we initialize the LMD-GCM with warm/moist conditions prescribed with simple scaling laws and assuming energy conservation.2) For moderate-size events (5km < Dimpactor < 50km, N ~ 3x103) we use the SOVA hydrocode for short-term modelling of impact cratering. It provides us with post-impact temperature fields, injection of volatiles, ejecta and dust distribution that serve as input for the LMD-GCM.3

  8. Effects of field-of-view restriction on manoeuvring in a 3-D environment.

    PubMed

    Toet, A; Jansen, S E M; Delleman, N J

    2008-03-01

    Field-of-view (FOV) restrictions are known to affect human behaviour and to degrade performance for a range of different tasks. However, the relationship between human locomotion performance in complex environments and FOV size is currently not fully known. This paper examined the effects of FOV restrictions on the performance of participants manoeuvring through an obstacle course with horizontal and vertical barriers. All FOV restrictions tested (the horizontal FOV was either 30 degrees , 75 degrees or 120 degrees , while the vertical FOV was always 48 degrees ) significantly reduced performance compared to the unrestricted condition. Both the time and the number of footsteps needed to traverse the entire obstacle course increased with a decreasing FOV size. The relationship between FOV restriction and manoeuvring performance that was determined can be used to formulate requirements for FOV restricting devices that are deployed to perform time-limited human locomotion tasks in complex structured environments, such as night-vision goggles and head-mounted displays used in training and entertainment systems.

  9. 3-D Localization of Virtual Sound Sources: Effects of Visual Environment, Pointing Method, and Training

    PubMed Central

    Majdak, Piotr; Goupell, Matthew J.; Laback, Bernhard

    2010-01-01

    The ability to localize sound sources in three-dimensional space was tested in humans. In experiment 1, naive subjects listened to noises filtered with subject-specific head-related transfer functions. The tested conditions included the pointing method (head or manual pointing) and the visual environment (VE) (darkness or virtual VE). The localization performance was not significantly different between the pointing methods. The virtual VE significantly improved the horizontal precision and reduced the number of front-back confusions. These results show the benefit of using a virtual VE in sound localization tasks. In experiment 2, subjects were provided sound localization training. Over the course of training, the performance improved for all subjects, with the largest improvements occurring during the first 400 trials. The improvements beyond the first 400 trials were smaller. After the training, there was still no significant effect of pointing method, showing that the choice of either head- or manual-pointing method plays a minor role in sound localization performance. The results of experiment 2 reinforce the importance of perceptual training for at least 400 trials in sound localization studies. PMID:20139459

  10. Orbital driven impurity spin effect on the magnetic order of quasi-3D cupric oxide

    NASA Astrophysics Data System (ADS)

    Ganga, B. G.; Santhosh, P. N.; Nanda, B. R. K.

    2017-04-01

    Density functional calculations are performed to study the magnetic order of the severely distorted square planar cupric oxide (CuO) and local spin disorder in it in the presence of the transition metal impurities M (=Cr, Mn, Fe, Co and Ni). The distortion in the crystal structure, arisen to reduce the band energy by minimizing the covalent interaction, creates two crisscrossing zigzag spin-1/2 chains. From the spin dimer analysis we find that while the spin chain along ≤ft[1 0 \\bar{1}\\right] has strong Heisenberg type antiferromagnetic coupling (J ~ 127 meV), along ≤ft[1 0 1\\right] it exhibits weak, but robust, ferromagnetic coupling (J ~ 9 meV) mediated by reminiscent p-d covalent interactions. The impurity effect on the magnetic ordering is independent of M and purely orbital driven. If the given spin-state of M is such that the {{d}{{x2}-{{y}2}}} orbital is spin-polarized, then the original long-range ordering is maintained. However, if {{d}{{x2}-{{y}2}}} orbital is unoccupied, the absence of corresponding covalent interaction breaks the weak ferromagnetic coupling and a spin-flip takes place at the impurity site leading to breakdown of the long range magnetic ordering.

  11. Doppler effects on 3-D non-LTE radiation transport and emission spectra.

    SciTech Connect

    Giuliani, J. L.; Davis, J.; DasGupta, A.; Apruzese, John P.; Jennings, Christopher A.; Clark, R. W.; Ampleford, David J.; Bailey, James E.; Thornhill, Joseph W.; Cuneo, Michael Edward; Rochau, Gregory Alan; Coverdale, Christine Anne; Jones, Brent Manley; Hansen, Stephanie B.

    2010-10-01

    Spatially and temporally resolved X-ray emission lines contain information about temperatures, densities, velocities, and the gradients in a plasma. Extracting this information from optically thick lines emitted from complex ions in dynamic, three-dimensional, non-LTE plasmas requires self-consistent accounting for both non-LTE atomic physics and non-local radiative transfer. We present a brief description of a hybrid-structure spectroscopic atomic model coupled to an iterative tabular on-the-spot treatment of radiative transfer that can be applied to plasmas of arbitrary material composition, conditions, and geometries. The effects of Doppler line shifts on the self-consistent radiative transfer within the plasma and the emergent emission and absorption spectra are included in the model. Sample calculations for a two-level atom in a uniform cylindrical plasma are given, showing reasonable agreement with more sophisticated transport models and illustrating the potential complexity - or richness - of radially resolved emission lines from an imploding cylindrical plasma. Also presented is a comparison of modeled L- and K-shell spectra to temporally and radially resolved emission data from a Cu:Ni plasma. Finally, some shortcomings of the model and possible paths for improvement are discussed.

  12. Orbital driven impurity spin effect on the magnetic order of quasi-3D cupric oxide.

    PubMed

    Ganga, B G; Santhosh, P N; Nanda, B R K

    2017-04-20

    Density functional calculations are performed to study the magnetic order of the severely distorted square planar cupric oxide (CuO) and local spin disorder in it in the presence of the transition metal impurities M (=Cr, Mn, Fe, Co and Ni). The distortion in the crystal structure, arisen to reduce the band energy by minimizing the covalent interaction, creates two crisscrossing zigzag spin-1/2 chains. From the spin dimer analysis we find that while the spin chain along [Formula: see text] has strong Heisenberg type antiferromagnetic coupling (J ~ 127 meV), along [Formula: see text] it exhibits weak, but robust, ferromagnetic coupling (J ~ 9 meV) mediated by reminiscent p-d covalent interactions. The impurity effect on the magnetic ordering is independent of M and purely orbital driven. If the given spin-state of M is such that the [Formula: see text] orbital is spin-polarized, then the original long-range ordering is maintained. However, if [Formula: see text] orbital is unoccupied, the absence of corresponding covalent interaction breaks the weak ferromagnetic coupling and a spin-flip takes place at the impurity site leading to breakdown of the long range magnetic ordering.

  13. The Effect of Dissipation Mechanism on X-line Spreading in 3D Magnetic

    NASA Astrophysics Data System (ADS)

    Shepherd, L. S.; Cassak, P.; Phan, T.; Shay, M. A.; Gosling, J. T.

    2012-12-01

    Naturally occurring magnetic reconnection generally begins in a spatially localized region and spreads in the direction perpendicular to the reconnection plane as time progresses. Reconnection spreading is associated with dawn-dusk asymmetries during substorms in the magnetotail and has been observed in two-ribbon flares (such as the Bastille Day flare) and laboratory experiments at the Versatile Toroidal Facility (VTF) and the Magnetic Reconnection eXperiment (MRX). It was suggested that X-line spreading is necessary to explain the existence of X-lines extending more than 390 Earth radii (Phan et al., Nature, 404, 848, 2006). Previous numerical studies exploring the spreading of localized magnetic reconnection exclusively addressed collisionless (Hall) reconnection. Here, we address the effect of dissipation mechanism has on X-line spreading with and without a guide field. We compare previous results with simulations using three alternate phases of reconnection - Sweet-Parker reconnection, collisional reconnection with secondary islands, and reconnection with anomalous resistivity. We present results from three-dimensional resistive magnetohydrodynamic numerical simulations to address the nature of X-line spreading. Applications to reconnection in the solar wind and corona will be discussed.

  14. Effect of 3D Polarization profiles on polarization measurements and colliding beam experiments

    SciTech Connect

    Fischer, W.; Bazilevsky, A.

    2011-08-18

    The development of polarization profiles are the primary reason for the loss of average polarization. Polarization profiles have been parametrized with a Gaussian distribution. We derive the effect of 3-dimensional polarization profiles on the measured polarization in polarimeters, as well as the observed polarization and the figure of merit in single and double spin experiments. Examples from RHIC are provided. The Relativistic Heavy Ion Collider (RHIC) is the only collider of spin polarized protons. During beam acceleration and storage profiles of the polarization P develop, which affect the polarization measured in a polarimeter, and the polarization and figure of merit (FOM) in colliding beam experiments. We calculate these for profiles in all dimensions, and give examples for RHIC. Like in RHIC we call the two colliding beams Blue and Yellow. We use the overbar to designate intensity-weighted averages in polarimeters (e.g. {bar P}), and angle brackets to designate luminosity-weighted averages in colliding beam experiments (e.g.

    ).

  15. The effects of aponeurosis geometry on strain injury susceptibility explored with a 3D muscle model.

    PubMed

    Rehorn, Michael R; Blemker, Silvia S

    2010-09-17

    In the musculoskeletal system, some muscles are injured more frequently than others. For example, the biceps femoris longhead (BFLH) is the most commonly injured hamstring muscle. It is thought that acute injuries result from large strains within the muscle tissue, but the mechanism behind this type of strain injury is still poorly understood. The purpose of this study was to build computational models to analyze the stretch distributions within the BFLH muscle and to explore the effects of aponeurosis geometry on the magnitude and location of peak stretches within the model. We created a three-dimensional finite element (FE) model of the BFLH based on magnetic resonance (MR) images. We also created a series of simplified models with a similar geometry to the MR-based model. We analyzed the stretches predicted by the MR-based model during lengthening contractions to determine the region of peak local fiber stretch. The peak along-fiber stretch was 1.64 and was located adjacent to the proximal myotendinous junction (MTJ). In contrast, the average along-fiber stretch across all the muscle tissue was 0.95. By analyzing the simple models, we found that varying the dimensions of the aponeuroses (width, length, and thickness) had a substantial impact on the location and magnitude of peak stretches within the muscle. Specifically, the difference in widths between the proximal and distal aponeurosis in the BFLH contributed most to the location and magnitude of peak stretch, as decreasing the proximal aponeurosis width by 80% increased peak average stretches along the proximal MTJ by greater than 60% while slightly decreasing stretches along the distal MTJ. These results suggest that the aponeurosis morphology of the BFLH plays a significant role in determining stretch distributions throughout the muscle. Furthermore, this study introduces the new hypothesis that aponeurosis widths may be important in determining muscle injury susceptibility.

  16. Effect of 3D stall-cells on the pressure distribution of a laminar NACA64-418 wing

    NASA Astrophysics Data System (ADS)

    Ragni, Daniele; Ferreira, Carlos

    2016-08-01

    A 3D stall-cell flow-field has been studied in a 4.8 aspect-ratio wing obtained by linear extrusion of a laminar NACA64-418 airfoil profile. The span-wise change in the velocity and pressure distribution along the wing has been quantified with respect to the development of cellular structures from 8° to 20° angle of attack. Oil-flow visualizations help localizing the regular cellular pattern in function of the angle of attack. Multi-plane stereoscopic PIV measurements obtained by traversing the entire setup along the wing span show that the flow separation is not span-wise uniform. The combination of different stereoscopic fields into a 3D volume of velocity data allows studying the global effect of the stall-cell pattern on the wing flow. Integration of the experimentally computed pressure gradient from the Navier-Stokes equation is employed to compute the span-wise distribution of the mean surface pressure. Comparison of the results with the ones obtained from pressure taps installed in the wing evidences a span-wise periodic loading on the wing. The periodic loading has maxima confined in the stream-wise direction between the location of the highest airfoil curvature and the one of the airfoil flow separation. Estimation of the periodic loading is found within 2-6 % of the sectional wing lift.

  17. The effect of porosity on cell ingrowth into accurately defined, laser-made, polylactide-based 3D scaffolds

    NASA Astrophysics Data System (ADS)

    Danilevicius, Paulius; Georgiadi, Leoni; Pateman, Christopher J.; Claeyssens, Frederik; Chatzinikolaidou, Maria; Farsari, Maria

    2015-05-01

    The aim of this study is to demonstrate the accuracy required for the investigation of the role of solid scaffolds' porosity in cell proliferation. We therefore present a qualitative investigation into the effect of porosity on MC3T3-E1 pre-osteoblastic cell ingrowth of three-dimensional (3D) scaffolds fabricated by direct femtosecond laser writing. The material we used is a purpose made photosensitive pre-polymer based on polylactide. We designed and fabricated complex, geometry-controlled 3D scaffolds with pore sizes ranging from 25 to 110 μm, representing porosities 70%, 82%, 86%, and 90%. The 70% porosity scaffolds did not support cell growth initially and in the long term. For the other porosities, we found a strong adhesion of the pre-osteoblastic cells from the first hours after seeding and a remarkable proliferation increase after 3 weeks and up to 8 weeks. The 86% porosity scaffolds exhibited a higher efficiency compared to 82% and 90%. In addition, bulk material degradation studies showed that the employed, highly-acrylated polylactide is degradable. These findings support the potential use of the proposed material and the scaffold fabrication technique in bone tissue engineering.

  18. Cells in 3D matrices under interstitial flow: effects of extracellular matrix alignment on cell shear stress and drag forces.

    PubMed

    Pedersen, John A; Lichter, Seth; Swartz, Melody A

    2010-03-22

    Interstitial flow is an important regulator of various cell behaviors both in vitro and in vivo, yet the forces that fluid flow imposes on cells embedded in a 3D extracellular matrix (ECM), and the effects of matrix architecture on those forces, are not well understood. Here, we demonstrate how fiber alignment can affect the shear and pressure forces on the cell and ECM. Using computational fluid dynamics simulations, we show that while the solutions of the Brinkman equation accurately estimate the average fluid shear stress and the drag forces on a cell within a 3D fibrous medium, the distribution of shear stress on the cellular surface as well as the peak shear stresses remain intimately related to the pericellular fiber architecture and cannot be estimated using bulk-averaged properties. We demonstrate that perpendicular fiber alignment of the ECM yields lower shear stress and pressure forces on the cells and higher stresses on the ECM, leading to decreased permeability, while parallel fiber alignment leads to higher stresses on cells and increased permeability, as compared to a cubic lattice arrangement. The Spielman-Goren permeability relationships for fibrous media agreed well with CFD simulations of flow with explicitly considered fibers. These results suggest that the experimentally observed active remodeling of ECM fibers by fibroblasts under interstitial flow to a perpendicular alignment could serve to decrease the shear and drag forces on the cell.

  19. Array servo scanning micro EDM of 3D micro cavities

    NASA Astrophysics Data System (ADS)

    Tong, Hao; Li, Yong; Yi, Futing

    2010-12-01

    Micro electro discharge machining (Micro EDM) is a non-traditional processing technology with the special advantages of low set-up cost and few cutting force in machining any conductive materials regardless of their hardness. As well known, die-sinking EDM is unsuitable for machining the complex 3D micro cavity less than 1mm due to the high-priced fabrication of 3D microelectrode itself and its serous wear during EDM process. In our former study, a servo scanning 3D micro-EDM (3D SSMEDM) method was put forward, and our experiments showed it was available to fabricate complex 3D micro-cavities. In this study, in order to improve machining efficiency and consistency accuracy for array 3D micro-cavities, an array-servo-scanning 3D micro EDM (3D ASSMEDM) method is presented considering the complementary advantages of the 3D SSMEDM and the array micro electrodes with simple cross-section. During 3D ASSMEDM process, the array cavities designed by CAD / CAM system can be batch-manufactured by servo scanning layer by layer using array-rod-like micro tool electrodes, and the axial wear of the array electrodes is compensated in real time by keeping discharge gap. To verify the effectiveness of the 3D ASSMEDM, the array-triangle-micro cavities (side length 630 μm) are batch-manufactured on P-doped silicon by applying the array-micro-electrodes with square-cross-section fabricated by LIGA process. Our exploratory experiment shows that the 3D ASSMEDM provides a feasible approach for the batch-manufacture of 3D array-micro-cavities of conductive materials.

  20. Array servo scanning micro EDM of 3D micro cavities

    NASA Astrophysics Data System (ADS)

    Tong, Hao; Li, Yong; Yi, Futing

    2011-05-01

    Micro electro discharge machining (Micro EDM) is a non-traditional processing technology with the special advantages of low set-up cost and few cutting force in machining any conductive materials regardless of their hardness. As well known, die-sinking EDM is unsuitable for machining the complex 3D micro cavity less than 1mm due to the high-priced fabrication of 3D microelectrode itself and its serous wear during EDM process. In our former study, a servo scanning 3D micro-EDM (3D SSMEDM) method was put forward, and our experiments showed it was available to fabricate complex 3D micro-cavities. In this study, in order to improve machining efficiency and consistency accuracy for array 3D micro-cavities, an array-servo-scanning 3D micro EDM (3D ASSMEDM) method is presented considering the complementary advantages of the 3D SSMEDM and the array micro electrodes with simple cross-section. During 3D ASSMEDM process, the array cavities designed by CAD / CAM system can be batch-manufactured by servo scanning layer by layer using array-rod-like micro tool electrodes, and the axial wear of the array electrodes is compensated in real time by keeping discharge gap. To verify the effectiveness of the 3D ASSMEDM, the array-triangle-micro cavities (side length 630 μm) are batch-manufactured on P-doped silicon by applying the array-micro-electrodes with square-cross-section fabricated by LIGA process. Our exploratory experiment shows that the 3D ASSMEDM provides a feasible approach for the batch-manufacture of 3D array-micro-cavities of conductive materials.

  1. The effects of extracellular sugar extraction on the 3D-structure of biological soil crusts from different ecosystems

    NASA Astrophysics Data System (ADS)

    Felde, Vincent; Rossi, Federico; Colesie, Claudia; Uteau-Puschmann, Daniel; Felix-Henningsen, Peter; Peth, Stephan; De Philippis, Roberto

    2015-04-01

    Biological soil crusts (BSCs) play important roles in the hydrological cycles of many different ecosystems around the world. In arid and semi-arid regions, they alter the availability and redistribution of water. Especially in early successional stage BSCs, this feature can be attributed to the presence and characteristics of extracellular polymeric substances (EPS) that are excreted by the crusts' organisms. In a previous study, the extraction of EPS from BSCs of the SW United States lead to a significant change in their hydrological behavior, namely the sorptivity of water (Rossi et al. 2012). This was concluded to be the effect of a change in the pore structure of these crusts, which is why in this work we investigated the effect of the EPS-extraction on soil structure using 3D-computed micro-tomography (µCT). We studied different types of BSCs from Svalbard, Germany, Israel and South Africa with varying grain sizes and species compositions (from green algae to light and dark cyanobacterial crusts with and without lichens and/or mosses). Unlike other EPS-extraction methods, the one utilized here is aimed at removing the extracellular matrix from crust samples whilst acting non-destructively (Rossi et al. 2012). For every crust sample, we physically cut out a small piece (1cm) from a larger sample contained in Petri dish, and scanned it in a CT at a high resolution (voxel edge length: 7µm). After putting it back in the dish, approximately in the same former position, it was treated for EPS-extraction and then removed and scanned again in order to check for a possible effect of the EPS-extraction. Our results show that the utilized EPS-extraction method had varying extraction efficiencies: while in some cases the amount removed was barely significant, in other cases up to 50% of the total content was recovered. Notwithstanding, no difference in soil micro-structure could be detected, neither in total porosity, nor in the distribution of pore sizes, the

  2. A fully 3D atomistic quantum mechanical study on random dopant induced effects in 25nm MOSFETs

    SciTech Connect

    Wang, Lin-Wang; Jiang, Xiang-Wei; Deng, Hui-Xiong; Luo, Jun-Wei; Li, Shu-Shen; Wang, Lin-Wang; Xia, Jian-Bai

    2008-07-11

    We present a fully 3D atomistic quantum mechanical simulation for nanometered MOSFET using a coupled Schroedinger equation and Poisson equation approach. Empirical pseudopotential is used to represent the single particle Hamiltonian and linear combination of bulk band (LCBB) method is used to solve the million atom Schroedinger's equation. We studied gate threshold fluctuations and threshold lowering due to the discrete dopant configurations. We compared our results with semiclassical simulation results. We found quantum mechanical effects increase the threshold fluctuation while decreases the threshold lowering. The increase of threshold fluctuation is in agreement with previous study based on approximated density gradient approach to represent the quantum mechanical effect. However, the decrease in threshold lowering is in contrast with the previous density gradient calculations.

  3. 3D and Education

    NASA Astrophysics Data System (ADS)

    Meulien Ohlmann, Odile

    2013-02-01

    Today the industry offers a chain of 3D products. Learning to "read" and to "create in 3D" becomes an issue of education of primary importance. 25 years professional experience in France, the United States and Germany, Odile Meulien set up a personal method of initiation to 3D creation that entails the spatial/temporal experience of the holographic visual. She will present some different tools and techniques used for this learning, their advantages and disadvantages, programs and issues of educational policies, constraints and expectations related to the development of new techniques for 3D imaging. Although the creation of display holograms is very much reduced compared to the creation of the 90ies, the holographic concept is spreading in all scientific, social, and artistic activities of our present time. She will also raise many questions: What means 3D? Is it communication? Is it perception? How the seeing and none seeing is interferes? What else has to be taken in consideration to communicate in 3D? How to handle the non visible relations of moving objects with subjects? Does this transform our model of exchange with others? What kind of interaction this has with our everyday life? Then come more practical questions: How to learn creating 3D visualization, to learn 3D grammar, 3D language, 3D thinking? What for? At what level? In which matter? for whom?

  4. Measuring the effects of fractionated radiation therapy in a 3D prostate cancer model system using SERS nanosensors.

    PubMed

    Camus, Victoria L; Stewart, Grant; Nailon, William H; McLaren, Duncan B; Campbell, Colin J

    2016-08-15

    Multicellular tumour spheroids (MTS) are three-dimensional cell cultures that possess their own microenvironments and provide a more meaningful model of tumour biology than monolayer cultures. As a result, MTS are becoming increasingly used as tumor models when measuring the efficiency of therapies. Monitoring the viability of live MTS is complicated by their 3D nature and conventional approaches such as fluorescence often require fixation and sectioning. In this paper we detail the use of Surface Enhanced Raman Spectroscopy (SERS) to measure the viability of MTS grown from prostate cancer (PC3) cells. Our results show that we can monitor loss of viability by measuring pH and redox potential in MTS and furthermore we demonstrate that SERS can be used to measure the effects of fractionation of a dose of radiotherapy in a way that has potential to inform treatment planning.

  5. Effect of wing mass in free flight by a butterfly-like 3D flapping wing-body model

    NASA Astrophysics Data System (ADS)

    Suzuki, Kosuke; Okada, Iori; Yoshino, Masato

    2016-11-01

    The effect of wing mass in free flight of a flapping wing is investigated by numerical simulations based on an immersed boundary-lattice Boltzmann method. We consider a butterfly-like 3D flapping wing-model consisting of two square wings with uniform mass density connected by a rod-shaped body. We simulate free flights of the wing-body model with various mass ratios of the wing to the whole of the model. As a result, it is found that the lift and thrust forces decrease as the mass ratio increases, since the body with a large mass ratio experiences large vertical and horizontal oscillations in one period and consequently the wing tip speed relatively decreases. In addition, we find the critical mass ratio between upward flight and downward flight for various Reynolds numbers. This work was supported by JSPS KAKENHI Grant Number JP16K18012.

  6. Effect of Refractive Status and Axial Length on Peripapillary Retinal Nerve Fibre Layer Thickness: An Analysis Using 3D OCT

    PubMed Central

    Sowmya, V.; Venkataramanan, V.R.

    2015-01-01

    Background Accurate measurement of retinal nerve fiber layer (RNFL) is now possible with the high resolution optical coherence tomography (OCT). Effect of refractive status of the eye on RNFL thickness may be relevant in the diagnosis of glaucoma and other optic nerve diseases. Aim To assess the RNFL thickness and compare its correlation with refractive status and axial length of the eye. Material and Methods Three hundred eyes of 150 patients were included in this study, who underwent RNFL analysis using TOPCON 3D OCT 2000. Analysis of variance has been used to find the significance of study parameters between the study groups. Results The study showed that refractive status/axial length affected the peripapillary RNFL thickness significantly. Conclusion The study suggests that the diagnostic accuracy of OCT may be improved by considering refractive status and axial length of the eye when RNFL is measured. PMID:26500931

  7. 3-D solar cells by electrochemical-deposited Se layer as extremely-thin absorber and hole conducting layer on nanocrystalline TiO2 electrode

    NASA Astrophysics Data System (ADS)

    Nguyen, Duy-Cuong; Tanaka, Souichirou; Nishino, Hitoshi; Manabe, Kyohei; Ito, Seigo

    2013-01-01

    A three-dimensional selenium solar cell with the structure of Au/Se/porous TiO2/compact TiO2/fluorine-doped tin oxide-coated glass plates was fabricated by an electrochemical deposition method of selenium, which can work for the extremely thin light absorber and the hole-conducting layer. The effect of experimental conditions, such as HCl and H2SeO3 in an electrochemical solution and TiO2 particle size of porous layers, was optimized. This kind of solar cell did not use any buffer layer between an n-type electrode (porous TiO2) and a p-type absorber layer (selenium). The crystallinity of the selenium after annealing at 200°C for 3 min in the air was significantly improved. The cells with a selenium layer deposited at concentrations of HCl = 11.5 mM and H2SeO3 = 20 mM showed the best performance, resulting in 1- to 2-nm thickness of the Se layer, short-circuit photocurrent density of 8.7 mA/cm2, open-circuit voltage of 0.65 V, fill factor of 0.53, and conversion efficiency of 3.0%.

  8. 3-D solar cells by electrochemical-deposited Se layer as extremely-thin absorber and hole conducting layer on nanocrystalline TiO2 electrode.

    PubMed

    Nguyen, Duy-Cuong; Tanaka, Souichirou; Nishino, Hitoshi; Manabe, Kyohei; Ito, Seigo

    2013-01-03

    A three-dimensional selenium solar cell with the structure of Au/Se/porous TiO2/compact TiO2/fluorine-doped tin oxide-coated glass plates was fabricated by an electrochemical deposition method of selenium, which can work for the extremely thin light absorber and the hole-conducting layer. The effect of experimental conditions, such as HCl and H2SeO3 in an electrochemical solution and TiO2 particle size of porous layers, was optimized. This kind of solar cell did not use any buffer layer between an n-type electrode (porous TiO2) and a p-type absorber layer (selenium). The crystallinity of the selenium after annealing at 200°C for 3 min in the air was significantly improved. The cells with a selenium layer deposited at concentrations of HCl = 11.5 mM and H2SeO3 = 20 mM showed the best performance, resulting in 1- to 2-nm thickness of the Se layer, short-circuit photocurrent density of 8.7 mA/cm2, open-circuit voltage of 0.65 V, fill factor of 0.53, and conversion efficiency of 3.0%.

  9. The effect of annealing on a 3D SnO2/graphene foam as an advanced lithium-ion battery anode

    PubMed Central

    Tian, Ran; Zhang, Yangyang; Chen, Zhihang; Duan, Huanan; Xu, Biyi; Guo, Yiping; Kang, Hongmei; Li, Hua; Liu, Hezhou

    2016-01-01

    3D annealed SnO2/graphene sheet foams (ASGFs) are synthesized by in situ self-assembly of graphene sheets prepared by mild chemical reduction. L-ascorbyl acid is used to effectively reduce the SnO2 nanoparticles/graphene oxide colloidal solution and form the 3D conductive graphene networks. The annealing treatment contributes to the formation of the Sn-O-C bonds between the SnO2 nanoparticles and the reduced graphene sheets, which improves the electrochemical performance of the foams. The ASGF has features of typical aerogels: low density (about 19 mg cm−3), smooth surface and porous structure. The ASGF anodes exhibit good specific capacity, excellent cycling stability and superior rate capability. The first reversible specific capacity is as high as 984.2 mAh g−1 at a specific current of 200 mA g−1. Even at the high specific current of 1000 mA g−1 after 150 cycles, the reversible specific capacity of ASGF is still as high as 533.7 mAh g−1, about twice as much as that of SGF (297.6 mAh g−1) after the same test. This synthesis method can be scaled up to prepare other metal oxides particles/ graphene sheet foams for high performance lithium-ion batteries, supercapacitors, and catalysts, etc. PMID:26754468

  10. A Correction Scheme for Thermal Conductivity Measurement Using the Comparative Cut-bar Technique Based on a 3D Numerical Simulation

    SciTech Connect

    Douglas W. Marshall; Changhu Xing; Charles Folsom; Colby Jensen; Heng Ban

    2014-05-01

    As an important factor affecting the accuracy of the thermal conductivity measurement, systematic (bias) error in the guarded comparative axial heat flow (cut-bar) method was mostly neglected by previous researches. This bias is due primarily to the thermal conductivity mismatch between sample and meter bars (reference), which is common for a sample of unknown thermal conductivity. A correction scheme, based on a finite element simulation of the measurement system, was proposed to reduce the magnitude of the overall measurement uncertainty. This scheme was experimentally validated by applying corrections on four types of sample measurements in which the specimen thermal conductivity is much smaller, slightly smaller, equal and much larger than that of the meter bar. As an alternative to the optimum guarding technique proposed before, the correction scheme can be used to minimize uncertainty contribution from the measurement system with non-optimal guarding conditions. It is especially necessary for large thermal conductivity mismatches between sample and meter bars.

  11. Non-Newtonian Fluids Spreading with Surface Tension Effect: 3D Numerical Analysis Using FEM and Experimental Study

    NASA Astrophysics Data System (ADS)

    Hu, Bin; Kieweg, Sarah

    2010-11-01

    Gravity-driven thin film flow down an incline is studied for optimal design of polymeric drug delivery vehicles, such as anti-HIV topical microbicides. We develop a 3D FEM model using non-Newtonian mechanics to model the flow of gels in response to gravity, surface tension and shear-thinning. Constant volume setup is applied within the lubrication approximation scope. The lengthwise profiles of the 3D model agree with our previous 2D finite difference model, while the transverse contact line patterns of the 3D model are compared to the experiments. With incorporation of surface tension, capillary ridges are observed at the leading front in both 2D and 3D models. Previously published studies show that capillary ridge can amplify the fingering instabilities in transverse direction. Sensitivity studies (2D & 3D) and experiments are carried out to describe the influence of surface tension and shear-thinning on capillary ridge and fingering instabilities.

  12. CONTINUUM INTENSITY AND [O i] SPECTRAL LINE PROFILES IN SOLAR 3D PHOTOSPHERIC MODELS: THE EFFECT OF MAGNETIC FIELDS

    SciTech Connect

    Fabbian, D.; Moreno-Insertis, F. E-mail: fmi@iac.es

    2015-04-01

    The importance of magnetic fields in three-dimensional (3D) magnetoconvection models of the Sun’s photosphere is investigated in terms of their influence on the continuum intensity at different viewing inclination angles and on the intensity profile of two [O i] spectral lines. We use the RH numerical radiative transfer code to perform a posteriori spectral synthesis on the same time series of magnetoconvection models used in our publications on the effect of magnetic fields on abundance determination. We obtain a good match of the synthetic disk-center continuum intensity to the absolute continuum values from the Fourier Transform Spectrometer (FTS) observational spectrum; the match of the center-to-limb variation synthetic data to observations is also good, thanks, in part, to the 3D radiation transfer capabilities of the RH code. The different levels of magnetic flux in the numerical time series do not modify the quality of the match. Concerning the targeted [O i] spectral lines, we find, instead, that magnetic fields lead to nonnegligible changes in the synthetic spectrum, with larger average magnetic flux causing both of the lines to become noticeably weaker. The photospheric oxygen abundance that one would derive if instead using nonmagnetic numerical models would thus be lower by a few to several centidex. The inclusion of magnetic fields is confirmed to be important for improving the current modeling of the Sun, here in particular in terms of spectral line formation and of deriving consistent chemical abundances. These results may shed further light on the still controversial issue regarding the precise value of the solar oxygen abundance.

  13. Effects of computing parameters and measurement locations on the estimation of 3D NPS in non-stationary MDCT images.

    PubMed

    Miéville, Frédéric A; Bolard, Gregory; Bulling, Shelley; Gudinchet, François; Bochud, François O; Verdun, François R

    2013-11-01

    The goal of this study was to investigate the impact of computing parameters and the location of volumes of interest (VOI) on the calculation of 3D noise power spectrum (NPS) in order to determine an optimal set of computing parameters and propose a robust method for evaluating the noise properties of imaging systems. Noise stationarity in noise volumes acquired with a water phantom on a 128-MDCT and a 320-MDCT scanner were analyzed in the spatial domain in order to define locally stationary VOIs. The influence of the computing parameters in the 3D NPS measurement: the sampling distances bx,y,z and the VOI lengths Lx,y,z, the number of VOIs NVOI and the structured noise were investigated to minimize measurement errors. The effect of the VOI locations on the NPS was also investigated. Results showed that the noise (standard deviation) varies more in the r-direction (phantom radius) than z-direction plane. A 25 × 25 × 40 mm(3) VOI associated with DFOV = 200 mm (Lx,y,z = 64, bx,y = 0.391 mm with 512 × 512 matrix) and a first-order detrending method to reduce structured noise led to an accurate NPS estimation. NPS estimated from off centered small VOIs had a directional dependency contrary to NPS obtained from large VOIs located in the center of the volume or from small VOIs located on a concentric circle. This showed that the VOI size and location play a major role in the determination of NPS when images are not stationary. This study emphasizes the need for consistent measurement methods to assess and compare image quality in CT.

  14. 3D FaceCam: a fast and accurate 3D facial imaging device for biometrics applications

    NASA Astrophysics Data System (ADS)

    Geng, Jason; Zhuang, Ping; May, Patrick; Yi, Steven; Tunnell, David

    2004-08-01

    Human faces are fundamentally three-dimensional (3D) objects, and each face has its unique 3D geometric profile. The 3D geometric features of a human face can be used, together with its 2D texture, for rapid and accurate face recognition purposes. Due to the lack of low-cost and robust 3D sensors and effective 3D facial recognition (FR) algorithms, almost all existing FR systems use 2D face images. Genex has developed 3D solutions that overcome the inherent problems in 2D while also addressing limitations in other 3D alternatives. One important aspect of our solution is a unique 3D camera (the 3D FaceCam) that combines multiple imaging sensors within a single compact device to provide instantaneous, ear-to-ear coverage of a human face. This 3D camera uses three high-resolution CCD sensors and a color encoded pattern projection system. The RGB color information from each pixel is used to compute the range data and generate an accurate 3D surface map. The imaging system uses no moving parts and combines multiple 3D views to provide detailed and complete 3D coverage of the entire face. Images are captured within a fraction of a second and full-frame 3D data is produced within a few seconds. This described method provides much better data coverage and accuracy in feature areas with sharp features or details (such as the nose and eyes). Using this 3D data, we have been able to demonstrate that a 3D approach can significantly improve the performance of facial recognition. We have conducted tests in which we have varied the lighting conditions and angle of image acquisition in the "field." These tests have shown that the matching results are significantly improved when enrolling a 3D image rather than a single 2D image. With its 3D solutions, Genex is working toward unlocking the promise of powerful 3D FR and transferring FR from a lab technology into a real-world biometric solution.

  15. Short and long time effects of low temperature Plasma Activated Media on 3D multicellular tumor spheroids

    NASA Astrophysics Data System (ADS)

    Judée, Florian; Fongia, Céline; Ducommun, Bernard; Yousfi, Mohammed; Lobjois, Valérie; Merbahi, Nofel

    2016-02-01

    This work investigates the regionalized antiproliferative effects of plasma-activated medium (PAM) on colon adenocarcinoma multicellular tumor spheroid (MCTS), a model that mimics 3D organization and regionalization of a microtumor region. PAM was generated by dielectric barrier plasma jet setup crossed by helium carrier gas. MCTS were transferred in PAM at various times after plasma exposure up to 48 hours and effect on MCTS growth and DNA damage were evaluated. We report the impact of plasma exposure duration and delay before transfer on MCTS growth and DNA damage. Local accumulation of DNA damage revealed by histone H2AX phosphorylation is observed on outermost layers and is dependent on plasma exposure. DNA damage is completely reverted by catalase addition indicating that H2O2 plays major role in observed genotoxic effect while growth inhibitory effect is maintained suggesting that it is due to others reactive species. SOD and D-mannitol scavengers also reduced DNA damage by 30% indicating that and OH* are involved in H2O2 formation. Finally, PAM is able to retain its cytotoxic and genotoxic activity upon storage at +4 °C or ‑80 °C. These results suggest that plasma activated media may be a promising new antitumor strategy for colorectal cancer tumors.

  16. Short and long time effects of low temperature Plasma Activated Media on 3D multicellular tumor spheroids

    PubMed Central

    Judée, Florian; Fongia, Céline; Ducommun, Bernard; Yousfi, Mohammed; Lobjois, Valérie; Merbahi, Nofel

    2016-01-01

    This work investigates the regionalized antiproliferative effects of plasma-activated medium (PAM) on colon adenocarcinoma multicellular tumor spheroid (MCTS), a model that mimics 3D organization and regionalization of a microtumor region. PAM was generated by dielectric barrier plasma jet setup crossed by helium carrier gas. MCTS were transferred in PAM at various times after plasma exposure up to 48 hours and effect on MCTS growth and DNA damage were evaluated. We report the impact of plasma exposure duration and delay before transfer on MCTS growth and DNA damage. Local accumulation of DNA damage revealed by histone H2AX phosphorylation is observed on outermost layers and is dependent on plasma exposure. DNA damage is completely reverted by catalase addition indicating that H2O2 plays major role in observed genotoxic effect while growth inhibitory effect is maintained suggesting that it is due to others reactive species. SOD and D-mannitol scavengers also reduced DNA damage by 30% indicating that and OH* are involved in H2O2 formation. Finally, PAM is able to retain its cytotoxic and genotoxic activity upon storage at +4 °C or −80 °C. These results suggest that plasma activated media may be a promising new antitumor strategy for colorectal cancer tumors. PMID:26898904

  17. EDITORIAL: 15th Workshop on MHD Stability Control: 3D Magnetic Field Effects in MHD Control 15th Workshop on MHD Stability Control: 3D Magnetic Field Effects in MHD Control

    NASA Astrophysics Data System (ADS)

    Buttery, Richard

    2011-08-01

    This annual workshop on MHD Stability Control has been held since 1996 with a focus on understanding and developing control of MHD instabilities for future fusion reactors. The workshop generally covers a wide range of stability topics: from disruptions, to tearing modes, error fields, ELMs, resistive wall modes (RWMs) and ideal MHD. It spans many device types, particularly tokamaks, stellarators and reversed field pinches, to pull out commonalities in the physics and improve understanding. In 2010 the workshop was held on 15-17 November at the University of Wisconsin in Madison and was combined with the annual US-Japan MHD Workshop. The theme was `3D Magnetic Field Effects in MHD Control', with a focus on multidisciplinary sessions exploring issues of plasma response to 3D fields, the manifestation of such fields in the plasma, and how they influence stability. This has been a topic of renewed interest, with utilisation of 3D fields for ELM control now planned in ITER, and a focus on the application of such fields for error field correction, disruption avoidance, and RWM control. Key issues included the physics of the interaction, types of coils and harmonic spectra needed to control instabilities, and subsidiary effects such as braking (or rotating) the plasma. More generally, a wider range of issues were discussed including RWM physics, tearing mode physics, disruption mitigation, ballooning stability, the snowflake divertor concept, and the line tied pinch! A novel innovation to the meeting was a panel discussion session, this year on Neoclassical Toroidal Viscosity, which ran well; more will be tried next year. In this special section of Plasma Physics and Controlled Fusion we present several of the invited and contributed papers from the 2010 workshop, which have been subject to the normal refereeing procedures of the journal. These papers give a sense of the exceptional quality of the presentations at this workshop, all of which may be found at http

  18. The World of 3-D.

    ERIC Educational Resources Information Center

    Mayshark, Robin K.

    1991-01-01

    Students explore three-dimensional properties by creating red and green wall decorations related to Christmas. Students examine why images seem to vibrate when red and green pieces are small and close together. Instructions to conduct the activity and construct 3-D glasses are given. (MDH)

  19. The Effect of Ethnicity on 2D and 3D Frontomaxillary Facial Angle Measurement in the First Trimester

    PubMed Central

    Clarke, Jill

    2013-01-01

    Objectives. To determine the existence and extent of ethnic differences in 2D or 3D fetal frontomaxillary facial angle (FMFA) measurements. Methods. During routine 11–14 weeks nuchal translucency screening undertaken in a private ultrasound practice in Sydney, Australia, 2D images and 3D volumes of the fetal profile were collected from consenting patients. FMFA was measured on a frozen 2D ultrasound image in the appropriate plane and, after a delay of at least 48 hours, was also measured on the reconstructed 3D ultrasound volume offline. Results. Overall 416 patients were included in the study; 220 Caucasian, 108 north Asian, 36 east Asian and 52 south Asian patients. Caucasians had significantly lower median FMFA measurements than Asians in both 2D (2.2°; P < 0.001) and 3D (3.4°; P < 0.001) images. Median 2D measurements were significantly higher than 3D measurements in the Caucasian and south Asian groups (P < 0.001 and P = 0.04), but not in north and east Asian groups (P = 0.08 and P = 0.41). Conclusions. Significant ethnic variations in both 2D and 3D FMFA measurements exist. These differences may indicate the need to establish ethnic-specific reference ranges for both 2D and 3D imaging. PMID:24288543

  20. 3D finite element analysis of nutrient distributions and cell viability in the intervertebral disc: effects of deformation and degeneration.

    PubMed

    Jackson, Alicia R; Huang, Chun-Yuh C; Brown, Mark D; Gu, Wei Yong

    2011-09-01

    The intervertebral disc (IVD) receives important nutrients, such as glucose, from surrounding blood vessels. Poor nutritional supply is believed to play a key role in disc degeneration. Several investigators have presented finite element models of the IVD to investigate disc nutrition; however, none has predicted nutrient levels and cell viability in the disc with a realistic 3D geometry and tissue properties coupled to mechanical deformation. Understanding how degeneration and loading affect nutrition and cell viability is necessary for elucidating the mechanisms of disc degeneration and low back pain. The objective of this study was to analyze the effects of disc degeneration and static deformation on glucose distributions and cell viability in the IVD using finite element analysis. A realistic 3D finite element model of the IVD was developed based on mechano-electrochemical mixture theory. In the model, the cellular metabolic activities and viability were related to nutrient concentrations, and transport properties of nutrients were dependent on tissue deformation. The effects of disc degeneration and mechanical compression on glucose concentrations and cell density distributions in the IVD were investigated. To examine effects of disc degeneration, tissue properties were altered to reflect those of degenerated tissue, including reduced water content, fixed charge density, height, and endplate permeability. Two mechanical loading conditions were also investigated: a reference (undeformed) case and a 10% static deformation case. In general, nutrient levels decreased moving away from the nutritional supply at the disc periphery. Minimum glucose levels were at the interface between the nucleus and annulus regions of the disc. Deformation caused a 6.2% decrease in the minimum glucose concentration in the normal IVD, while degeneration resulted in an 80% decrease. Although cell density was not affected in the undeformed normal disc, there was a decrease in cell

  1. 3D Imaging.

    ERIC Educational Resources Information Center

    Hastings, S. K.

    2002-01-01

    Discusses 3 D imaging as it relates to digital representations in virtual library collections. Highlights include X-ray computed tomography (X-ray CT); the National Science Foundation (NSF) Digital Library Initiatives; output peripherals; image retrieval systems, including metadata; and applications of 3 D imaging for libraries and museums. (LRW)

  2. Examination of Buoyancy-Reduction Effect in Induction-Heating Cookers by Using 3D Finite Element Method

    NASA Astrophysics Data System (ADS)

    Yonetsu, Daigo; Tanaka, Kazufumi; Hara, Takehisa

    In recent years, induction-heating (IH) cookers that can be used to heat nonmagnetic metals such as aluminum have been produced. Occasionally, a light pan moves on a glass plate due to buoyancy when heated by an IH cooker. In some IH cookers, an aluminum plate is mounted between the glass plate and the coil in order to reduce the buoyancy effect. The objective of this research is to evaluate the buoyancy-reduction effect and the heating effect of buoyancy-reduction plates. Eddy current analysis is carried out by 3D finite element method, and the electromagnetic force and the heat distribution on the heating plate are calculated. After this calculation is performed, the temperature distribution of the heating plate is calculated by heat transfer analysis. It is found that the shape, area, and the position of the buoyancy reduction plate strongly affect the buoyancy and the heat distribution. The impact of the shape, area, and position of the buoyancy reduction plate was quantified. The phenomena in the heating were elucidated qualitatively.

  3. Three-dimensional (3D) plasmonic hot spots for label-free sensing and effective photothermal killing of multiple drug resistant superbugs.

    PubMed

    Jones, Stacy; Sinha, Sudarson Sekhar; Pramanik, Avijit; Ray, Paresh Chandra

    2016-11-03

    Drug resistant superbug infection is one of the foremost threats to human health. Plasmonic nanoparticles can be used for ultrasensitive bio-imaging and photothermal killing by amplification of electromagnetic fields at nanoscale "hot spots". One of the main challenges to plasmonic imaging and photothermal killing is design of a plasmonic substrate with a large number of "hot spots". Driven by this need, this article reports design of a three-dimensional (3D) plasmonic "hot spot"-based substrate using gold nanoparticle attached hybrid graphene oxide (GO), free from the traditional 2D limitations. Experimental results show that the 3D substrate has capability for highly sensitive label-free sensing and generates high photothermal heat. Reported data using p-aminothiophenol conjugated 3D substrate show that the surface enhanced Raman spectroscopy (SERS) enhancement factor for the 3D "hot spot"-based substrate is more than two orders of magnitude greater than that for the two-dimensional (2D) substrate and five orders of magnitude greater than that for the zero-dimensional (0D) p-aminothiophenol conjugated gold nanoparticle. 3D-Finite-Difference Time-Domain (3D-FDTD) simulation calculations indicate that the SERS enhancement factor can be greater than 10(4) because of the bent assembly structure in the 3D substrate. Results demonstrate that the 3D-substrate-based SERS can be used for fingerprint identification of several multi-drug resistant superbugs with detection limits of 5 colony forming units per mL. Experimental data show that 785 nm near infrared (NIR) light generates around two times more photothermal heat for the 3D substrate with respect to the 2D substrate, and allows rapid and effective killing of 100% of the multi-drug resistant superbugs within 5 minutes.

  4. Highly effective surface-enhanced fluorescence substrates with roughened 3D flowerlike silver nanostructures fabricated in liquid crystalline phase

    NASA Astrophysics Data System (ADS)

    Zhang, Ying; Yang, Chengliang; Xiang, Xiangjun; Zhang, Peiguang; Peng, Zenghui; Cao, Zhaoliang; Mu, Quanquan; Xuan, Li

    2017-04-01

    Highly effective surface-enhanced fluorescence substrates with roughened 3D flowerlike silver nanostructures were fabricated by electrodeposition in liquid crystalline template which is simple and controllable. Due to the localized surface plasmon resonance of silver nanostructures, the substrates were used as surface enhanced fluorescence substrates. The morphology and optical properties of the substrates were studied. The fluorescence experiments of the Rhodamine 6G on the substrates for different growth times were carried out and the best enhancement factor of 181 was achieved. Eight substrates with the same growth conditions were used to study the reproducibility of the substrate which shows that the fluctuations are within 9%. This substrate was used in organic distributed feedback lasers and the amplified spontaneous emission of poly(2-methoxy-5-(2‧-ethyl-hexyloxy)-p-phenylenevinylene) was enhanced dramatically which means the reduced threshold and improved slope efficiency. Such easily fabricated flower-like silver nanostructure substrates with strong surface enhanced fluorescence effect and good reproducibility are good candidate for potential applications in optical imaging, biotechnology and material detections.

  5. Affective SSVEP BCI to effectively control 3D objects by using a prism array-based display

    NASA Astrophysics Data System (ADS)

    Mun, Sungchul; Park, Min-Chul

    2014-06-01

    3D objects with depth information can provide many benefits to users in education, surgery, and interactions. In particular, many studies have been done to enhance sense of reality in 3D interaction. Viewing and controlling stereoscopic 3D objects with crossed or uncrossed disparities, however, can cause visual fatigue due to the vergenceaccommodation conflict generally accepted in 3D research fields. In order to avoid the vergence-accommodation mismatch and provide a strong sense of presence to users, we apply a prism array-based display to presenting 3D objects. Emotional pictures were used as visual stimuli in control panels to increase information transfer rate and reduce false positives in controlling 3D objects. Involuntarily motivated selective attention by affective mechanism can enhance steady-state visually evoked potential (SSVEP) amplitude and lead to increased interaction efficiency. More attentional resources are allocated to affective pictures with high valence and arousal levels than to normal visual stimuli such as white-and-black oscillating squares and checkerboards. Among representative BCI control components (i.e., eventrelated potentials (ERP), event-related (de)synchronization (ERD/ERS), and SSVEP), SSVEP-based BCI was chosen in the following reasons. It shows high information transfer rates and takes a few minutes for users to control BCI system while few electrodes are required for obtaining reliable brainwave signals enough to capture users' intention. The proposed BCI methods are expected to enhance sense of reality in 3D space without causing critical visual fatigue to occur. In addition, people who are very susceptible to (auto) stereoscopic 3D may be able to use the affective BCI.

  6. Potential Geophysical Field Transformations and Combined 3D Modelling for Estimation the Seismic Site Effects on Example of Israel

    NASA Astrophysics Data System (ADS)

    Eppelbaum, Lev; Meirova, Tatiana

    2015-04-01

    It is well-known that the local seismic site effects may have a significant contribution to the intensity of damage and destruction (e.g., Hough et al., 1990; Regnier et al., 2000; Bonnefoy-Claudet et al., 2006; Haase et al., 2010). The thicknesses of sediments, which play a large role in amplification, usually are derived from seismic velocities. At the same time, thickness of sediments may be determined (or defined) on the basis of 3D combined gravity-magnetic modeling joined with available geological materials, seismic data and borehole section examination. Final result of such investigation is a 3D physical-geological model (PGM) reflecting main geological peculiarities of the area under study. Such a combined study needs in application of a reliable 3D mathematical algorithm of computation together with advanced methodology of 3D modeling. For this analysis the developed GSFC software was selected. The GSFC (Geological Space Field Calculation) program was developed for solving a direct 3-D gravity and magnetic prospecting problem under complex geological conditions (Khesin et al., 1996; Eppelbaum and Khesin, 2004). This program has been designed for computing the field of Δg (Bouguer, free-air or observed value anomalies), ΔZ, ΔX, ΔY , ΔT , as well as second derivatives of the gravitational potential under conditions of rugged relief and inclined magnetization. The geological space can be approximated by (1) three-dimensional, (2) semi-infinite bodies and (3) those infinite along the strike closed, L.H. non-closed, R.H. on-closed and open). Geological bodies are approximated by horizontal polygonal prisms. The program has the following main advantages (besides abovementioned ones): (1) Simultaneous computing of gravity and magnetic fields; (2) Description of the terrain relief by irregularly placed characteristic points; (3) Computation of the effect of the earth-air boundary by the method of selection directly in the process of interpretation; (4

  7. Effects of obliquely opposing and following currents on wave propagation in a new 3D wave-current basin

    NASA Astrophysics Data System (ADS)

    Lieske, Mike; Schlurmann, Torsten

    2016-04-01

    INTRODUCTION & MOTIVATION The design of structures in coastal and offshore areas and their maintenance are key components of coastal protection. Usually, assessments of processes and loads on coastal structures are derived from experiments with flow and wave parameters in separate physical models. However, Peregrin (1976) already points out that processes in natural shallow coastal waters flow and sea state processes do not occur separately, but influence each other nonlinearly. Kemp & Simons (1982) perform 2D laboratory tests and study the interactions between a turbulent flow and following waves. They highlight the significance of wave-induced changes in the current properties, especially in the mean flow profiles, and draw attention to turbulent fluctuations and bottom shear stresses. Kemp & Simons (1983) also study these processes and features with opposing waves. Studies on the wave-current interaction in three-dimensional space for a certain wave height, wave period and water depth were conducted by MacIver et al. (2006). The research focus is set on the investigation of long-crested waves on obliquely opposing and following currents in the new 3D wave-current basin. METHODOLOGY In a first step the flow analysis without waves is carried out and includes measurements of flow profiles in the sweet spot of the basin at predefined measurement positions. Five measuring points in the water column have been delineated in different water depths in order to obtain vertical flow profiles. For the characterization of the undisturbed flow properties in the basin, an uniformly distributed flow was generated in the wave basin. In the second step wave analysis without current, the unidirectional wave propagation and wave height were investigated for long-crested waves in intermediate wave conditions. In the sweet spot of the wave basin waves with three different wave directions, three wave periods and uniform wave steepness were examined. For evaluation, we applied a common

  8. Fast Li-Ion-Conducting Garnet-Related Li7–3xFexLa3Zr2O12 with Uncommon I4̅3d Structure

    PubMed Central

    2016-01-01

    Fast Li-ion-conducting Li oxide garnets receive a great deal of attention as they are suitable candidates for solid-state Li electrolytes. It was recently shown that Ga-stabilized Li7La3Zr2O12 crystallizes in the acentric cubic space group I4̅3d. This structure can be derived by a symmetry reduction of the garnet-type Ia3̅d structure, which is the most commonly found space group of Li oxide garnets and garnets in general. In this study, single-crystal X-ray diffraction confirms the presence of space group I4̅3d also for Li7–3xFexLa3Zr2O12. The crystal structure was characterized by X-ray powder diffraction, single-crystal X-ray diffraction, neutron powder diffraction, and Mößbauer spectroscopy. The crystal–chemical behavior of Fe3+ in Li7La3Zr2O12 is very similar to that of Ga3+. The symmetry reduction seems to be initiated by the ordering of Fe3+ onto the tetrahedral Li1 (12a) site of space group I4̅3d. Electrochemical impedance spectroscopy measurements showed a Li-ion bulk conductivity of up to 1.38 × 10–3 S cm–1 at room temperature, which is among the highest values reported for this group of materials. PMID:27570369

  9. TNF/S C3/D CONDUCT: A simulation model of the Army's command, control, communications, and intelligence (C3I) process

    NASA Astrophysics Data System (ADS)

    Noon, T. V.; Marx, E.

    1981-11-01

    A computer model (CONDUCT) has been developed that simulates corps and subordinate command, control, communications, and intelligence C3I functions with particular emphasis on the integration of the new generation of intelligence, surveillance, and target-acquisition systems within the developing 1982 and 1986 force structure. CONDUCT is an event-by-event simulation model written in GPSS-V (General Purpose Simulation System), representing the combat and combat support command/staff elements and communications nodes/nets for the operations and intelligence functions within a type corps. Maneuver and engineer units are represented to platoon level, artillery units to battery level, and target-acquisition and Combat Electronics Warfare Intelligence (CEWI) units to sensor team level. Major command posts and operations centers are subdivided into their primary functional areas. Also given are results from the initial 16 hr combat simulation.

  10. Effect of 3D physiological loading and motion on elastohydrodynamic lubrication of metal-on-metal total hip replacements.

    PubMed

    Gao, Leiming; Wang, Fengcai; Yang, Peiran; Jin, Zhongmin

    2009-07-01

    An elastohydrodynamic lubrication (EHL) simulation of a metal-on-metal (MOM) total hip implant was presented, considering both steady state and transient physiological loading and motion gait cycle in all three directions. The governing equations were solved numerically by the multi-grid method and fast Fourier transform in spherical coordinates, and full numerical solutions were presented included the pressure and film thickness distribution. Despite small variations in the magnitude of 3D resultant load, the horizontal anterior-posterior (AP) and medial-lateral (ML) load components were found to translate the contact area substantially in the corresponding direction and consequently to result in significant squeeze-film actions. For a cup positioned anatomically at 45 degrees , the variation of the resultant load was shown unlikely to cause the edge contact. The contact area was found within the cup dimensions of 70-130 degrees and 90-150 degrees in the AP and ML direction respectively even under the largest translations. Under walking conditions, the horizontal load components had a significant impact on the lubrication film due to the squeeze-film effect. The time-dependent film thickness was increased by the horizontal translation and decreased during the reverse of this translation caused by the multi-direction of the AP load during walking. The minimum film thickness of 12-20 nm was found at 0.4s and around the location at (95, 125) degrees. During the whole walking cycle both the average and centre film thickness were found obviously increased to a range of 40-65 nm, compared with the range of 25-55 nm under one load (vertical) and one motion (flexion-extension) condition, which suggested the lubrication in the current MOM hip implant was improved under 3D physiological loading and motion. This study suggested the lubrication performance especially the film thickness distribution should vary greatly under different operating conditions and the time and

  11. The effect of rheological approximations on the dynamics and topography in 3D subduction-collision models

    NASA Astrophysics Data System (ADS)

    Pusok, Adina E.; Kaus, Boris J. P.; Popov, Anton A.

    2016-04-01

    Most of the major mountain belts and orogenic plateaus are found within the overlying plate of active or fossil subduction and/or collision zones. Moreover, they evolve differently from one another as the result of specific combinations of surface and mantle processes. These differences arise for several reasons, such as different rheological properties, different amounts of regional isostatic compensation, and different mechanisms by which forces are applied to the convergent plates. Previous 3D geodynamic models of subduction/collision processes have used various rheological approximations, making numerical results difficult to compare, since there is no clear image on the extent of these approximations on the dynamics. Here, we employ the code LaMEM to perform high-resolution long-term 3D simulations of subduction/continental collision in an integrated lithospheric and upper-mantle scale model. We test the effect of rheological approximations on mantle and lithosphere dynamics in a geometrically simplified model setup that resembles a tectonic map of the India-Asia collision zone. We use the "sticky-air" approach to allow for the development of topography and the dynamics of subduction and collision is entirely driven by slab-pull (i.e. "free subduction"). The models exhibit a wide range of behaviours depending on the rheological law employed: from linear to temperature-dependent visco-elasto-plastic rheology that takes into account both diffusion and dislocation creep. For example, we find that slab dynamics varies drastically between end member models: in viscous approximations, slab detachment is slow following a viscous thinning, while for a non-linear visco-elasto-plastic rheology, slab detachment is relatively fast, inducing strong mantle flow in the slab window. We also examine the stress states in the subducting and overriding plates and topography evolution in the upper plate, and we discuss the implications on lithosphere dynamics at convergent margins

  12. 3D modeling of human cancer: A PEG-fibrin hydrogel system to study the role of tumor microenvironment and recapitulate the in vivo effect of oncolytic adenovirus.

    PubMed

    Del Bufalo, Francesca; Manzo, Teresa; Hoyos, Valentina; Yagyu, Shigeki; Caruana, Ignazio; Jacot, Jeffrey; Benavides, Omar; Rosen, Daniel; Brenner, Malcolm K

    2016-04-01

    Interactions between malignant and stromal cells and the 3D spatial architecture of the tumor both substantially modify tumor behavior, including the responses to small molecule drugs and biological therapies. Conventional 2D culture systems cannot replicate this complexity. To overcome these limitations and more accurately model solid tumors, we developed a highly versatile 3D PEG-fibrin hydrogel model of human lung adenocarcinoma. Our model relevantly recapitulates the effect of oncolytic adenovirus; tumor responses in this setting nearly reproduce those observed in vivo. We have also validated the use of this model for complex, long-term, 3D cultures of cancer cells and their stroma (fibroblasts and endothelial cells). Both tumor proliferation and invasiveness were enhanced in the presence of stromal components. These results validate our 3D hydrogel model as a relevant platform to study cancer biology and tumor responses to biological treatments.

  13. The effect of tumour size on drug transport and uptake in 3-D tumour models reconstructed from magnetic resonance images

    PubMed Central

    Zhan, Wenbo; Gedroyc, Wladyslaw

    2017-01-01

    Drug transport and its uptake by tumour cells are strongly dependent on tumour properties, which vary in different types of solid tumours. By simulating the key physical and biochemical processes, a numerical study has been carried out to investigate the transport of anti-cancer drugs in 3-D tumour models of different sizes. The therapeutic efficacy for each tumour is evaluated by using a pharmacodynamics model based on the predicted intracellular drug concentration. Simulation results demonstrate that interstitial fluid pressure and interstitial fluid loss vary non-linearly with tumour size. Transvascular drug exchange, driven by the concentration gradient of unbound drug between blood and interstitial fluid, is more efficient in small tumours, owing to the low spatial-mean interstitial fluid pressure and dense microvasculature. However, this has a detrimental effect on therapeutic efficacy over longer periods as a result of enhanced reverse diffusion of drug to the blood circulation after the cessation of drug infusion, causing more rapid loss of drug in small tumours. PMID:28212385

  14. Effect of 3d-transition metal doping on the shielding behavior of barium borate glasses: a spectroscopic study.

    PubMed

    ElBatal, H A; Abdelghany, A M; Ghoneim, N A; ElBatal, F H

    2014-12-10

    UV-visible and FT infrared spectra were measured for prepared samples before and after gamma irradiation. Base undoped barium borate glass of the basic composition (BaO 40%-B2O3 60mol.%) reveals strong charge transfer UV absorption bands which are related to unavoidable trace iron impurities (Fe(3+)) within the chemical raw materials. 3d transition metal (TM)-doped glasses exhibit extra characteristic absorption bands due to each TM in its specific valence or coordinate state. The optical spectra show that TM ions favor generally the presence in the high valence or tetrahedral coordination state in barium borate host glass. Infrared absorption bands of all prepared glasses reveal the appearance of both triangular BO3 units and tetrahedral BO4 units within their characteristic vibrational modes and the TM-ions cause minor effects because of the low doping level introduced (0.2%). Gamma irradiation of the undoped barium borate glass increases the intensity of the UV absorption together with the generation of an induced broad visible band at about 580nm. These changes are correlated with suggested photochemical reactions of trace iron impurities together with the generation of positive hole center (BHC or OHC) within the visible region through generated electrons and positive holes during the irradiation process.

  15. First Lunar Wake Passage of ARTEMIS: Discrimination of Wake Effects and Solar Wind Fluctuations by 3D Hybrid Simulations

    NASA Technical Reports Server (NTRS)

    Wiehle, S.; Plaschke, F.; Motschmann, U.; Glassmeier, K. H.; Auster, H. U.; Angelopoulos, V.; Mueller, J.; Kriegel, H.; Georgescu, E.; Halekas, J.; Sibeck, D. G.; McFadden, J. P.

    2011-01-01

    The spacecraft P1 of the new ARTEMIS (Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun) mission passed the lunar wake for the first time on February 13, 2010. We present magnetic field and plasma data of this event and results of 3D hybrid simulations. As the solar wind magnetic field was highly dynamic during the passage, a simulation with stationary solar wind input cannot distinguish whether distortions were caused by these solar wind variations or by the lunar wake; therefore, a dynamic real-time simulation of the flyby has been performed. The input values of this simulation are taken from NASA OMNI data and adapted to the P1 data, resulting in a good agreement between simulation and measurements. Combined with the stationary simulation showing non-transient lunar wake structures, a separation of solar wind and wake effects is achieved. An anisotropy in the magnitude of the plasma bulk flow velocity caused by a non-vanishing magnetic field component parallel to the solar wind flow and perturbations created by counterstreaming ions in the lunar wake are observed in data and simulations. The simulations help to interpret the data granting us the opportunity to examine the entire lunar plasma environment and, thus, extending the possibilities of measurements alone: A comparison of a simulation cross section to theoretical predictions of MHD wave propagation shows that all three basic MHD modes are present in the lunar wake and that their expansion governs the lunar wake refilling process.

  16. Effects of spacer orientations on the cake formation during membrane fouling: Quantitative analysis based on 3D OCT imaging.

    PubMed

    Liu, Xin; Li, Weiyi; Chong, Tzyy Haur; Fane, Anthony G

    2017-03-01

    Spacer design plays an important role in improving the performance of membrane processes for water/wastewater treatment. This work focused on a fundamental issue of spacer design, i.e., investigating the effects of spacer orientations on the fouling behavior during a membrane process. A series of fouling experiments with different spacer orientation were carried out to in situ characterize the formation of a cake layer in a spacer unit cell via 3D optical coherence tomography (OCT) imaging. The cake layers formed at different times were digitalized for quantitatively analyzing the variation in the cake morphology as a function of time. In particular, the local deposition rates were evaluated to determine the active regions where the instantaneous changes in deposit thickness were significant. The characterization results indicate that varying the spacer orientation could substantially change the evolution of membrane fouling by particulate foulants and thereby result in a cake layer with various morphologies; the competition between growth and erosion at different locations would instantaneously respond to the micro-hydrodynamic environment that might change with time. This work confirms that the OCT-based characterization method is a powerful tool for exploring novel spacer design.

  17. Insights into the effects of oblique extension on continental rift interaction from 3D analogue and numerical models

    NASA Astrophysics Data System (ADS)

    Zwaan, Frank; Schreurs, Guido; Naliboff, John; Buiter, Susanne J. H.

    2016-12-01

    Continental rifts often develop from linkage of distinct rift segments under varying degrees of extension obliquity. These rift segments arise from rift initiation at non-aligned crustal heterogeneities and need to interact to develop a full-scale rift system. Here, we test the effects of 1) oblique extension and 2) initial heterogeneity (seed) offset on continental rift interaction with the use of an improved analogue model set-up. X-ray computer tomography (CT) techniques are used to analyse the 3D models through time and the results are compared with additional numerical models and natural examples. The experimental results reveal that increasing extension obliquity strongly changes rift segment structures from wide rifts in orthogonal settings to narrower rifts with oblique internal structures under oblique extension conditions to narrow strike-slip dominated systems towards the strike-slip domain. We also find that both decreasing seed offset and increasing extension obliquity promote hard linkage of rift segments through the formation of continuous rift boundary faults at the surface. (Initial) soft linkage through the formation of relay ramps is more likely when seed offset increases or extension is more orthogonal. Rather than linking at depth, the rift boundary faults curve around each other at depth and merge towards the surface to form a continuous trough. Orthogonal extension promotes the formation of intra-rift horsts, which may provide hydrocarbon traps in nature.

  18. Effects of sintering temperature on morphology and mechanical characteristics of 3D printed porous titanium used as dental implant.

    PubMed

    Gagg, Graham; Ghassemieh, Elaheh; Wiria, Florencia Edith

    2013-10-01

    Porous titanium samples were manufactured using the 3D printing and sintering method in order to determine the effects of final sintering temperature on morphology and mechanical properties. Cylindrical samples were printed and split into groups according to a final sintering temperature (FST). Irregular geometry samples were also printed and split into groups according to their FST. The cylindrical samples were used to determine part shrinkage, in compressive tests to provide stress-strain data, in microCT scans to provide internal morphology data and for optical microscopy to determine surface morphology. All of the samples were used in microhardness testing to establish the hardness. Below 1100 °C FST, shrinkage was in the region of 20% but increased to approximately 30% by a FST of 1300 °C. Porosity varied from a maximum of approximately 65% at the surface to the region of 30% internally. Between 97 and 99% of the internal porosity is interconnected. Average pore size varied between 24 μm at the surface and 19 μm internally. Sample hardness increased to in excess of 300 HV0.05 with increasing FST while samples with an FST of below 1250 °C produced an elastic-brittle stress/strain curve and samples above this displayed elastic-plastic behaviour. Yield strength increased significantly through the range of sintering temperatures while the Young's modulus remained fairly consistent.

  19. The effect of CT dose on glenohumeral joint congruency measurements using 3D reconstructed patient-specific bone models

    NASA Astrophysics Data System (ADS)

    Lalone, Emily A.; Fox, Anne-Marie V.; Kedgley, Angela E.; Jenkyn, Thomas R.; King, Graham J. W.; Athwal, George S.; Johnson, James A.; Peters, Terry M.

    2011-10-01

    The study of joint congruency at the glenohumeral joint of the shoulder using computed tomography (CT) and three-dimensional (3D) reconstructions of joint surfaces is an area of significant clinical interest. However, ionizing radiation delivered to patients during CT examinations is much higher than other types of radiological imaging. The shoulder represents a significant challenge for this modality as it is adjacent to the thyroid gland and breast tissue. The objective of this study was to determine the optimal CT scanning techniques that would minimize radiation dose while accurately quantifying joint congruency of the shoulder. The results suggest that only one-tenth of the standard applied total current (mA) and a pitch ratio of 1.375:1 was necessary to produce joint congruency values consistent with that of the higher dose scans. Using the CT scanning techniques examined in this study, the effective dose applied to the shoulder to quantify joint congruency was reduced by 88.9% compared to standard clinical CT imaging techniques.

  20. 3D-Printing of inverted pyramid suspending architecture for pyroelectric infrared detectors with inhibited microphonic effect

    NASA Astrophysics Data System (ADS)

    Xu, Qing; Zhao, Xiangyong; Li, Xiaobing; Deng, Hao; Yan, Hong; Yang, Linrong; Di, Wenning; Luo, Haosu; Neumann, Norbert

    2016-05-01

    A sensitive chip with ultralow dielectric loss based on Mn doped PMNT (71/29) has been proposed for high-end pyroelectric devices. The dielectric loss at 1 kHz is 0.005%, one order lower than the minimum value reported so far. The detective figure of merit (Fd) is up to 92.6 × 10-5 Pa-1/2 at 1 kHz and 53.5 × 10-5 Pa-1/2 at 10 Hz, respectively. In addition, an inverted pyramid suspending architecture for supporting the sensitive chip has been designed and manufactured by 3D printing technology. The combination of this sensitive chip and the proposed suspending architecture largely enhances the performance of the pyroelectric detectors. The responsivity and specific detectivity are 669,811 V/W and 3.32 × 109 cm Hz1/2/W at 10 Hz, respectively, 1.9 times and 1.5 times higher than those of the highest values in literature. Furthermore, the microphonic effect can be largely inhibited according to the theoretical and experimental analysis. This architecture will have promising applications in high-end and stable pyroelectric infrared detectors.

  1. 3D Finite Element Modelling for the investigation of the cavity effect in extensometric rock-deformation measurements

    NASA Astrophysics Data System (ADS)

    Kis, M.; Detzky, G.; Koppán, A.

    2012-04-01

    phenomenon in general. Authors calculated the deformations of a simple-geometry 3D cavity, which is caused by variable gravity loads. Dependence of the cavity effect on changing of distinct elastic properties in categorized models has been investigated. Authors introduced qualifying parameter fields calculated using the results of the FE modelling (nodal displacements as a model answer for the gravity load), in order to characterize the effect. Modelling results can be used as an estimation not only for the absolute cavity effect rate of the intended arrangement, furthermore the sensitivity of the given system against a particular geometric property. As an application example finite element modelling were carried out in order to estimate the influence of the complicated cavity system surrounding the "Budapest-Matyashegy" Gravity and Geodynamical Observatory of the Eotvos Lorand Geophysical Institute of Hungary.

  2. The asteroseismic surface effect from a grid of 3D convection simulations - I. Frequency shifts from convective expansion of stellar atmospheres

    NASA Astrophysics Data System (ADS)

    Trampedach, Regner; Aarslev, Magnus J.; Houdek, Günter; Collet, Remo; Christensen-Dalsgaard, Jørgen; Stein, Robert F.; Asplund, Martin

    2017-03-01

    We analyse the effect on adiabatic stellar oscillation frequencies of replacing the near-surface layers in 1D stellar structure models with averaged 3D stellar surface convection simulations. The main difference is an expansion of the atmosphere by 3D convection, expected to explain a major part of the asteroseismic surface effect, a systematic overestimation of p-mode frequencies due to inadequate surface physics. We employ pairs of 1D stellar envelope models and 3D simulations from a previous calibration of the mixing-length parameter, α. That calibration constitutes the hitherto most consistent matching of 1D models to 3D simulations, ensuring that their differences are not spurious, but entirely due to the 3D nature of convection. The resulting frequency shift is identified as the structural part of the surface effect. The important, typically non-adiabatic, modal components of the surface effect are not included in this analysis, but relegated to future papers. Evaluating the structural surface effect at the frequency of maximum mode amplitude, νmax , we find shifts from δν = -0.8 μHz for giants at log g = 2.2 to - 35 μHz for a (Teff = 6901 K, log g = 4.29) dwarf. The fractional effect δν(νmax )/νmax , ranges from -0.1 per cent for a cool dwarf (4185 K, 4.74) to -6 per cent for a warm giant (4962 K, 2.20).

  3. The Effect of 3D Visual Simulator on Children’s Visual Acuity - A Pilot Study Comparing Two Different Modalities

    PubMed Central

    Ide, Takeshi; Ishikawa, Mariko; Tsubota, Kazuo; Miyao, Masaru

    2013-01-01

    Purpose : To evaluate the efficacy of two non-surgical interventions of vision improvement in children. Methods : A prospective, randomized, pilot study to compare fogging method and the use of head mounted 3D display. Subjects were children, between 5 to 15 years old, with normal best corrected visual acuity (BCVA) and up to -3D myopia. Subjects played a video game as near point work, and received one of the two methods of treatments. Measurements of uncorrected far visual acuity (UCVA), refraction with autorefractometer, and subjective accommodative amplitude were taken 3 times, at the baseline, after the near work, and after the treatment. Results : Both methods applied after near work, improved UCVA. Head mounted 3D display group showed significant improvement in UCVA and resulted in better UCVA than baseline. Fogging group showed improvement in subjective accommodative amplitude. While 3D display group did not show change in the refraction, fogging group’s myopic refraction showed significant increase indicating the eyes showed myopic change of eyes after near work and treatment. Discussion : Despite our lack of clear knowledge in the mechanisms, both methods improved UCVA after the treatments. The improvement in UCVA was not correlated to measured refraction values. Conclusion : UCVA after near work can be improved by repeating near and distant accommodation by fogging and 3D image viewing, although at the different degrees. Further investigation on mechanisms of improvements and their clinical significance are warranted. PMID:24222810

  4. Stable Li Plating/Stripping Electrochemistry Realized by a Hybrid Li Reservoir in Spherical Carbon Granules with 3D Conducting Skeletons.

    PubMed

    Ye, Huan; Xin, Sen; Yin, Ya-Xia; Li, Jin-Yi; Guo, Yu-Guo; Wan, Li-Jun

    2017-04-14

    Lithium metal is a promising battery anode. However, inhomogeneous mass and charge transfers across the Li/electrolyte interface result in formation of dendritic Li and "dead" Li, and an unstable solid electrolyte interphase, which incur serious problems to impede its service in rechargeable batteries. Here, we show that the above problems can be mitigated by regulating the interfacial mass/charge transfer. The key to our strategy is hybrid Li storage in onion-like, graphitized spherical C granules wired on a three-dimensional conducting skeleton, which enhances the negativity of surface charge of the C host to contribute to a uniform Li plating while also forming stable Li/C intercalation compounds to offset any irreversible Li loss during cycling. As a result, the anode shows a suppressed dendrite formation and a high Li utilization >95%, enabling a practical Li battery to strike a long lifespan of 1000 cycles at a surplus Li of merely 5%.

  5. YouDash3D: exploring stereoscopic 3D gaming for 3D movie theaters

    NASA Astrophysics Data System (ADS)

    Schild, Jonas; Seele, Sven; Masuch, Maic

    2012-03-01

    Along with the success of the digitally revived stereoscopic cinema, events beyond 3D movies become attractive for movie theater operators, i.e. interactive 3D games. In this paper, we present a case that explores possible challenges and solutions for interactive 3D games to be played by a movie theater audience. We analyze the setting and showcase current issues related to lighting and interaction. Our second focus is to provide gameplay mechanics that make special use of stereoscopy, especially depth-based game design. Based on these results, we present YouDash3D, a game prototype that explores public stereoscopic gameplay in a reduced kiosk setup. It features live 3D HD video stream of a professional stereo camera rig rendered in a real-time game scene. We use the effect to place the stereoscopic effigies of players into the digital game. The game showcases how stereoscopic vision can provide for a novel depth-based game mechanic. Projected trigger zones and distributed clusters of the audience video allow for easy adaptation to larger audiences and 3D movie theater gaming.

  6. An interactive multiview 3D display system

    NASA Astrophysics Data System (ADS)

    Zhang, Zhaoxing; Geng, Zheng; Zhang, Mei; Dong, Hui

    2013-03-01

    The progresses in 3D display systems and user interaction technologies will help more effective 3D visualization of 3D information. They yield a realistic representation of 3D objects and simplifies our understanding to the complexity of 3D objects and spatial relationship among them. In this paper, we describe an autostereoscopic multiview 3D display system with capability of real-time user interaction. Design principle of this autostereoscopic multiview 3D display system is presented, together with the details of its hardware/software architecture. A prototype is built and tested based upon multi-projectors and horizontal optical anisotropic display structure. Experimental results illustrate the effectiveness of this novel 3D display and user interaction system.

  7. A study of the effects of degraded imagery on tactical 3D model generation using structure-from-motion

    NASA Astrophysics Data System (ADS)

    Bolick, Leslie; Harguess, Josh

    2016-05-01

    An emerging technology in the realm of airborne intelligence, surveillance, and reconnaissance (ISR) systems is structure-from-motion (SfM), which enables the creation of three-dimensional (3D) point clouds and 3D models from two-dimensional (2D) imagery. There are several existing tools, such as VisualSFM and open source project OpenSfM, to assist in this process, however, it is well-known that pristine imagery is usually required to create meaningful 3D data from the imagery. In military applications, such as the use of unmanned aerial vehicles (UAV) for surveillance operations, imagery is rarely pristine. Therefore, we present an analysis of structure-from-motion packages on imagery that has been degraded in a controlled manner.

  8. Left Ventricular Myocardial Segmentation in 3-D Ultrasound Recordings: Effect of Different Endocardial and Epicardial Coupling Strategies.

    PubMed

    Pedrosa, Joao; Barbosa, Daniel; Heyde, Brecht; Schnell, Frederic; Rosner, Assami; Claus, Piet; D'hooge, Jan

    2017-03-01

    Cardiac volume/function assessment remains a critical step in daily cardiology, and 3-D ultrasound plays an increasingly important role. Though development of automatic endocardial segmentation methods has received much attention, the same cannot be said about epicardial segmentation, in spite of the importance of full myocardial segmentation. In this paper, different ways of coupling the endocardial and epicardial segmentations are contrasted and compared with uncoupled segmentation. For this purpose, the B-spline explicit active surfaces framework was used; 27 3-D echocardiographic images were used to validate the different coupling strategies, which were compared with manual contouring of the endocardial and epicardial borders performed by an expert. It is shown that an independent segmentation of the endocardium followed by an epicardial segmentation coupled to the endocardium is the most advantageous. In this way, a framework for fully automatic 3-D myocardial segmentation is proposed using a novel coupling strategy.

  9. 2-D Versus 3-D Magnetotelluric Data Interpretation

    NASA Astrophysics Data System (ADS)

    Ledo, Juanjo

    2005-09-01

    In recent years, the number of publications dealing with the mathematical and physical 3-D aspects of the magnetotelluric method has increased drastically. However, field experiments on a grid are often impractical and surveys are frequently restricted to single or widely separated profiles. So, in many cases we find ourselves with the following question: is the applicability of the 2-D hypothesis valid to extract geoelectric and geological information from real 3-D environments? The aim of this paper is to explore a few instructive but general situations to understand the basics of a 2-D interpretation of 3-D magnetotelluric data and to determine which data subset (TE-mode or TM-mode) is best for obtaining the electrical conductivity distribution of the subsurface using 2-D techniques. A review of the mathematical and physical fundamentals of the electromagnetic fields generated by a simple 3-D structure allows us to prioritise the choice of modes in a 2-D interpretation of responses influenced by 3-D structures. This analysis is corroborated by numerical results from synthetic models and by real data acquired by other authors. One important result of this analysis is that the mode most unaffected by 3-D effects depends on the position of the 3-D structure with respect to the regional 2-D strike direction. When the 3-D body is normal to the regional strike, the TE-mode is affected mainly by galvanic effects, while the TM-mode is affected by galvanic and inductive effects. In this case, a 2-D interpretation of the TM-mode is prone to error. When the 3-D body is parallel to the regional 2-D strike the TE-mode is affected by galvanic and inductive effects and the TM-mode is affected mainly by galvanic effects, making it more suitable for 2-D interpretation. In general, a wise 2-D interpretation of 3-D magnetotelluric data can be a guide to a reasonable geological interpretation.

  10. Effect of ROI filtering in 3D cone-beam rotational angiography on organ dose and effective dose in cerebral investigations.

    PubMed

    Göpfert, Fabian; Schmidt, Ralph; Wulff, Jörg; Zink, Klemens

    2015-03-08

    The assessment of intracranial aneurysms is increasingly performed using three-dimensional cone-beam rotational angiography (3D CBRA). To reduce the dose to the patient during 3D CBRA procedures, filtered region-of-interest imaging (FROI) is presented in literature to be an effective technique as the dose in regions of low interest is reduced, while high image quality is preserved in the ROI. The purpose of this study was to quantify the benefit of FROI imaging during a typical 3D CBRA procedure in a patient's head region. A cone-beam rotational angiography unit (Infinix) was modeled in GMctdospp, an EGSnrc-based Monte Carlo software, which calculates patient dose distributions in rotational computed tomography. Kodak Lanex, a gadolinium compound, was chosen to be the ROI filter material. The adult female ICRP reference phantom was integrated in GMctdospp to calculate organ and effective doses in simulations of FROI-CBRA examinations. During the Monte Carlo simulations, different parameters as the ROI filter thickness, the ROI opening size, the tube voltage, and the isocenter position were varied. The results showed that the reduction in dose clearly depends on these parameters. Comparing the reduction in organ dose in standard 3D CBRA and FROI-CBRA, a maximum reduction of about 60%-80% could be achieved with a small sized ROI filter and about 40%-70% of the dose could be saved using a ROI filter with a large opening. Further we could show that dose reduction strongly depends on filter thickness, the location of the organ in the radiated area, and the position of the isocenter. As a consequence, dose reduction partially differs from theoretically calculated values by a factor up to 1.6. The effective dose could be reduced to a minimum of about 40%. Due to the fact that standard 3D CBRA is only used for the assessment of aneurysms at present and, thus, most of the patient dose originates from the aneurysm treatment (with 2D techniques) itself, the dose reduction

  11. 3D Flow Visualization Using Texture Advection

    NASA Technical Reports Server (NTRS)

    Kao, David; Zhang, Bing; Kim, Kwansik; Pang, Alex; Moran, Pat (Technical Monitor)

    2001-01-01

    Texture advection is an effective tool for animating and investigating 2D flows. In this paper, we discuss how this technique can be extended to 3D flows. In particular, we examine the use of 3D and 4D textures on 3D synthetic and computational fluid dynamics flow fields.

  12. Conducting Effective Staff Development Workshops

    ERIC Educational Resources Information Center

    Bishop, Kay; Janczak, Sue

    2005-01-01

    Staff development workshops conducted by library media specialists can assist teachers to integrate information literacy skills and technology into their curricula. Guidelines are presented on the planning and implementation of such workshops.

  13. Trans-Hudsonian far-field deformation effects in the Rae foreland: An integrated geological-3D magnetic model

    NASA Astrophysics Data System (ADS)

    Percival, J. A.; Tschirhart, V.

    2017-03-01

    The intracratonic Rae cover sequence, deposited ca. 2.2-1.9 Ga, forms a useful marker for unravelling tectonic events that affected the Archean Rae Province at ca.2.0, 1.9 and 1.85 Ga. Polyphase deformation is recognized within the Rae cover rocks, including the 70 × 10 km Montresor belt, and attributed to distal effects of the ca. 1.85 Ga Trans-Hudson orogeny. In this contribution we explore the 3D geometry and structural history of the Montresor belt, previously considered to be a simple syncline lying unconformably on Archean basement. New geological, geophysical and geochronological results define a more complex history in which lower Montresor units were thrust-imbricated with basement gneisses and metamorphosed to the amphibolite facies. Mid-to upper greenschist facies upper Montresor units, exposed in an open synform, are superficially less deformed. However, using high-resolution aeromagnetic data and distinct magnetic marker units considered proxies for bedding, we constructed a set of forward models to explore the three-dimensional geometry of the belt. The re-analysis outlines a set of pre-synform structures defined by low-angle truncations of the magnetic markers. Geometric relationships indicate the presence of at least three faults at low angles to bedding, interpreted as D1 piggy-back thrusts, and bracketed by available geochronology between 1.924 and 1.87 Ga. D1 strain in the upper Montresor strata is significantly less intense than that further south in Rae cover rocks, consistent with a more distal foreland setting during the Trans-Hudson orogeny. The Montresor belt preserves a record of the Trans-Hudson tectonic style at relatively shallow crustal levels as a result of its foreland setting and structural history including a syn-orogenic extensional detachment event.

  14. Increase in the Random Dopant Induced Threshold Fluctuations and Lowering in Sub 100 nm MOSFETs Due to Quantum Effects: A 3-D Density-Gradient Simulation Study

    NASA Technical Reports Server (NTRS)

    Asenov, Asen; Slavcheva, G.; Brown, A. R.; Davies, J. H.; Saini, S.

    2000-01-01

    In this paper we present a detailed simulation study of the influence of quantum mechanical effects in the inversion layer on random dopant induced threshold voltage fluctuations and lowering in sub 100 nm MOSFETs. The simulations have been performed using a 3-D implementation of the density gradient (DG) formalism incorporated in our established 3-D atomistic simulation approach. This results in a self-consistent 3-D quantum mechanical picture, which implies not only the vertical inversion layer quantisation but also the lateral confinement effects related to current filamentation in the 'valleys' of the random potential fluctuations. We have shown that the net result of including quantum mechanical effects, while considering statistical dopant fluctuations, is an increase in both threshold voltage fluctuations and lowering. At the same time, the random dopant induced threshold voltage lowering partially compensates for the quantum mechanical threshold voltage shift in aggressively scaled MOSFETs with ultrathin gate oxides.

  15. 3D co-cultures of keratinocytes and melanocytes and cytoprotective effects on keratinocytes against reactive oxygen species by insect virus-derived protein microcrystals.

    PubMed

    Shimabukuro, Junji; Yamaoka, Ayako; Murata, Ken-Ichi; Kotani, Eiji; Hirano, Tomoko; Nakajima, Yumiko; Matsumoto, Goichi; Mori, Hajime

    2014-09-01

    Stable protein microcrystals called polyhedra are produced by certain insect viruses. Cytokines, such as fibroblast growth factors (FGFs), can be immobilized within polyhedra. Here, we investigated three-dimensional (3D) co-cultures of keratinocytes and melanocytes on collagen gel containing FGF-2 and FGF-7 polyhedra. Melanocytes were observed to reside at the base of the 3D cell culture and melanin was also typically observed in the lower layer. The 3D cell culture model with FGF-2 and FGF-7 polyhedra was a useful in vitro model of the epidermis due to effective melanogenesis, proliferation and differentiation of keratinocytes. FGF-7 polyhedra showed a potent cytoprotective effect when keratinocytes were treated with menadione, which is a generator of reactive oxygen species. The cytoprotective effect was activated by the inositol triphosphate kinase-Akt pathway leading to upregulation of the antioxidant enzymes superoxide dismutase and peroxiredoxin 6.

  16. Effects of Scattering on the Temperature Stratification in 3D Model Atmospheres of Late-Type Stars

    NASA Astrophysics Data System (ADS)

    Collet, R.; Hayek, W.; Asplund, M.

    2011-12-01

    Three-dimensional (3D) radiative hydrodynamic model atmospheres of metal-poor late-type stars predict cooler upper photospheric stratifications than their one-dimensional (1D) counterparts. This property of 3D model atmospheres affects the determination of elemental abundances from temperature-sensitive spectral features, with important consequences for galactic chemical evolution studies. In this contribution, we investigate the impact of different approximations of scattering in the solution of the radiative transfer equation on the temperature stratification of 3D model atmospheres of metal-poor red giants. We use the BIFROST code to construct 3D model atmospheres of metal-poor red giants using three different approximations of scattering. First, we self-consistently solve the radiative transfer equation for the general case of a source function with a coherent scattering term; second, we solve the radiative transfer equation assuming a Planckian source function and neglecting altogether the contribution of continuum scattering to extinction in the optically thin layers; third, we assume a Planckian source function and treat continuum scattering as pure absorption everywhere in the simulation's domain. We find that the second approach produces very similar temperature structures with cool upper photospheric layers as when treating scattering correctly, and at a much lower computational cost. In contrast, treating scattering as pure absorption leads to significantly hotter and shallower temperature stratifications.

  17. A pilot study of the photoprotective effect of almond phytochemicals in a 3D human skin equivalent

    Technology Transfer Automated Retrieval System (TEKTRAN)

    UV exposure causes oxidative stress, inflammation, erythema, and skin cancer. Alpha-Tocopherol (AT) and polyphenols (AP) present in almonds may serve as photoprotectants. Our objectives were to assess the feasibility of using a 3D human skin equivalent (HSE) in photoprotectant research and to deter...

  18. Airborne particle emission of a commercial 3D printer: the effect of filament material and printing temperature.

    PubMed

    Stabile, L; Scungio, M; Buonanno, G; Arpino, F; Ficco, G

    2017-03-01

    The knowledge of exposure to the airborne particle emitted from three-dimensional (3D) printing activities is becoming a crucial issue due to the relevant spreading of such devices in recent years. To this end, a low-cost desktop 3D printer based on fused deposition modeling (FDM) principle was used. Particle number, alveolar-deposited surface area, and mass concentrations were measured continuously during printing processes to evaluate particle emission rates (ERs) and factors. Particle number distribution measurements were also performed to characterize the size of the emitted particles. Ten different materials and different extrusion temperatures were considered in the survey. Results showed that all the investigated materials emit particles in the ultrafine range (with a mode in the 10-30-nm range), whereas no emission of super-micron particles was detected for all the materials under investigation. The emission was affected strongly by the extrusion temperature. In fact, the ERs increase as the extrusion temperature increases. Emission rates up to 1×10(12)  particles min(-1) were calculated. Such high ERs were estimated to cause large alveolar surface area dose in workers when 3D activities run. In fact, a 40-min-long 3D printing was found to cause doses up to 200 mm(2) .

  19. 3D printing PLGA: a quantitative examination of the effects of polymer composition and printing parameters on print resolution.

    PubMed

    Guo, Ting; Holzberg, Timothy R; Lim, Casey G; Gao, Feng; Gargava, Ankit; Trachtenberg, Jordan E; Mikos, Antonios G; Fisher, John P

    2017-04-12

    In the past few decades, 3D printing has played a significant role in fabricating scaffolds with consistent, complex structure that meet patient-specific needs in future clinical applications. Although many studies have contributed to this emerging field of additive manufacturing, which includes material development and computer-aided scaffold design, current quantitative analyses do not correlate material properties, printing parameters, and printing outcomes to a great extent. A model that correlates these properties has tremendous potential to standardize 3D printing for tissue engineering and biomaterial science. In this study, we printed poly(lactic-co-glycolic acid) (PLGA) utilizing a direct melt extrusion technique without additional ingredients. We investigated PLGA with various lactic acid:glycolic acid (LA:GA) molecular weight ratios and end caps to demonstrate the dependence of the extrusion process on the polymer composition. Micro-computed tomography was then used to evaluate printed scaffolds containing different LA:GA ratios, composed of different fiber patterns, and processed under different printing conditions. We built a statistical model to reveal the correlation and predominant factors that determine printing precision. Our model showed a strong linear relationship between the actual and predicted precision under different combinations of printing conditions and material compositions. This quantitative examination establishes a significant foreground to 3D print biomaterials following a systematic fabrication procedure. Additionally, our proposed statistical models can be applied to couple specific biomaterials and 3D printing applications for patient implants with particular requirements.

  20. The Story in the Mind: The Effect of 3D Gameplay on the Structuring of Written L2 Narratives

    ERIC Educational Resources Information Center

    Neville, David O.

    2015-01-01

    The article reports on a mixed-methods study evaluating the use of a three-dimensional digital game-based language learning (3D-DGBLL) environment to teach German two-way prepositions and specialized vocabulary within a simulated real-world context of German recycling and waste management systems. The study assumed that goal-directed player…

  1. Effectiveness of Applying 2D Static Depictions and 3D Animations to Orthographic Views Learning in Graphical Course

    ERIC Educational Resources Information Center

    Wu, Chih-Fu; Chiang, Ming-Chin

    2013-01-01

    This study provides experiment results as an educational reference for instructors to help student obtain a better way to learn orthographic views in graphical course. A visual experiment was held to explore the comprehensive differences between 2D static and 3D animation object features; the goal was to reduce the possible misunderstanding…

  2. 3-D Seismic Interpretation

    NASA Astrophysics Data System (ADS)

    Moore, Gregory F.

    2009-05-01

    This volume is a brief introduction aimed at those who wish to gain a basic and relatively quick understanding of the interpretation of three-dimensional (3-D) seismic reflection data. The book is well written, clearly illustrated, and easy to follow. Enough elementary mathematics are presented for a basic understanding of seismic methods, but more complex mathematical derivations are avoided. References are listed for readers interested in more advanced explanations. After a brief introduction, the book logically begins with a succinct chapter on modern 3-D seismic data acquisition and processing. Standard 3-D acquisition methods are presented, and an appendix expands on more recent acquisition techniques, such as multiple-azimuth and wide-azimuth acquisition. Although this chapter covers the basics of standard time processing quite well, there is only a single sentence about prestack depth imaging, and anisotropic processing is not mentioned at all, even though both techniques are now becoming standard.

  3. Radiochromic 3D Detectors

    NASA Astrophysics Data System (ADS)

    Oldham, Mark

    2015-01-01

    Radiochromic materials exhibit a colour change when exposed to ionising radiation. Radiochromic film has been used for clinical dosimetry for many years and increasingly so recently, as films of higher sensitivities have become available. The two principle advantages of radiochromic dosimetry include greater tissue equivalence (radiologically) and the lack of requirement for development of the colour change. In a radiochromic material, the colour change arises direct from ionising interactions affecting dye molecules, without requiring any latent chemical, optical or thermal development, with important implications for increased accuracy and convenience. It is only relatively recently however, that 3D radiochromic dosimetry has become possible. In this article we review recent developments and the current state-of-the-art of 3D radiochromic dosimetry, and the potential for a more comprehensive solution for the verification of complex radiation therapy treatments, and 3D dose measurement in general.

  4. Effect of segmentation errors on 3D-to-2D registration of implant models in X-ray images.

    PubMed

    Mahfouz, Mohamed R; Hoff, William A; Komistek, Richard D; Dennis, Douglas A

    2005-02-01

    In many biomedical applications, it is desirable to estimate the three-dimensional (3D) position and orientation (pose) of a metallic rigid object (such as a knee or hip implant) from its projection in a two-dimensional (2D) X-ray image. If the geometry of the object is known, as well as the details of the image formation process, then the pose of the object with respect to the sensor can be determined. A common method for 3D-to-2D registration is to first segment the silhouette contour from the X-ray image; that is, identify all points in the image that belong to the 2D silhouette and not to the background. This segmentation step is then followed by a search for the 3D pose that will best match the observed contour with a predicted contour. Although the silhouette of a metallic object is often clearly visible in an X-ray image, adjacent tissue and occlusions can make the exact location of the silhouette contour difficult to determine in places. Occlusion can occur when another object (such as another implant component) partially blocks the view of the object of interest. In this paper, we argue that common methods for segmentation can produce errors in the location of the 2D contour, and hence errors in the resulting 3D estimate of the pose. We show, on a typical fluoroscopy image of a knee implant component, that interactive and automatic methods for segmentation result in segmented contours that vary significantly. We show how the variability in the 2D contours (quantified by two different metrics) corresponds to variability in the 3D poses. Finally, we illustrate how traditional segmentation methods can fail completely in the (not uncommon) cases of images with occlusion.

  5. Bootstrapping 3D fermions

    DOE PAGES

    Iliesiu, Luca; Kos, Filip; Poland, David; ...

    2016-03-17

    We study the conformal bootstrap for a 4-point function of fermions <ψψψψ> in 3D. We first introduce an embedding formalism for 3D spinors and compute the conformal blocks appearing in fermion 4-point functions. Using these results, we find general bounds on the dimensions of operators appearing in the ψ × ψ OPE, and also on the central charge CT. We observe features in our bounds that coincide with scaling dimensions in the GrossNeveu models at large N. Finally, we also speculate that other features could coincide with a fermionic CFT containing no relevant scalar operators.

  6. Bootstrapping 3D fermions

    SciTech Connect

    Iliesiu, Luca; Kos, Filip; Poland, David; Pufu, Silviu S.; Simmons-Duffin, David; Yacoby, Ran

    2016-03-17

    We study the conformal bootstrap for a 4-point function of fermions <ψψψψ> in 3D. We first introduce an embedding formalism for 3D spinors and compute the conformal blocks appearing in fermion 4-point functions. Using these results, we find general bounds on the dimensions of operators appearing in the ψ × ψ OPE, and also on the central charge CT. We observe features in our bounds that coincide with scaling dimensions in the GrossNeveu models at large N. Finally, we also speculate that other features could coincide with a fermionic CFT containing no relevant scalar operators.

  7. 3-D Extensions for Trustworthy Systems

    DTIC Science & Technology

    2011-01-01

    3- D Extensions for Trustworthy Systems (Invited Paper) Ted Huffmire∗, Timothy Levin∗, Cynthia Irvine∗, Ryan Kastner† and Timothy Sherwood...address these problems, we propose an approach to trustworthy system development based on 3- D integration, an emerging chip fabrication technique in...which two or more integrated circuit dies are fabricated individually and then combined into a single stack using vertical conductive posts. With 3- D

  8. Venus in 3D

    NASA Technical Reports Server (NTRS)

    Plaut, Jeffrey J.

    1993-01-01

    Stereographic images of the surface of Venus which enable geologists to reconstruct the details of the planet's evolution are discussed. The 120-meter resolution of these 3D images make it possible to construct digital topographic maps from which precise measurements can be made of the heights, depths, slopes, and volumes of geologic structures.

  9. 3D photoacoustic imaging

    NASA Astrophysics Data System (ADS)

    Carson, Jeffrey J. L.; Roumeliotis, Michael; Chaudhary, Govind; Stodilka, Robert Z.; Anastasio, Mark A.

    2010-06-01

    Our group has concentrated on development of a 3D photoacoustic imaging system for biomedical imaging research. The technology employs a sparse parallel detection scheme and specialized reconstruction software to obtain 3D optical images using a single laser pulse. With the technology we have been able to capture 3D movies of translating point targets and rotating line targets. The current limitation of our 3D photoacoustic imaging approach is its inability ability to reconstruct complex objects in the field of view. This is primarily due to the relatively small number of projections used to reconstruct objects. However, in many photoacoustic imaging situations, only a few objects may be present in the field of view and these objects may have very high contrast compared to background. That is, the objects have sparse properties. Therefore, our work had two objectives: (i) to utilize mathematical tools to evaluate 3D photoacoustic imaging performance, and (ii) to test image reconstruction algorithms that prefer sparseness in the reconstructed images. Our approach was to utilize singular value decomposition techniques to study the imaging operator of the system and evaluate the complexity of objects that could potentially be reconstructed. We also compared the performance of two image reconstruction algorithms (algebraic reconstruction and l1-norm techniques) at reconstructing objects of increasing sparseness. We observed that for a 15-element detection scheme, the number of measureable singular vectors representative of the imaging operator was consistent with the demonstrated ability to reconstruct point and line targets in the field of view. We also observed that the l1-norm reconstruction technique, which is known to prefer sparseness in reconstructed images, was superior to the algebraic reconstruction technique. Based on these findings, we concluded (i) that singular value decomposition of the imaging operator provides valuable insight into the capabilities of

  10. The effect of parameters of equilibrium-based 3-D biomechanical models on extracted muscle synergies during isometric lumbar exertion.

    PubMed

    Eskandari, A H; Sedaghat-Nejad, E; Rashedi, E; Sedighi, A; Arjmand, N; Parnianpour, M

    2016-04-11

    A hallmark of more advanced models is their higher details of trunk muscles represented by a larger number of muscles. The question is if in reality we control these muscles individually as independent agents or we control groups of them called "synergy". To address this, we employed a 3-D biomechanical model of the spine with 18 trunk muscles that satisfied equilibrium conditions at L4/5, with different cost functions. The solutions of several 2-D and 3-D tasks were arranged in a data matrix and the synergies were computed by using non-negative matrix factorization (NMF) algorithms. Variance accounted for (VAF) was used to evaluate the number of synergies that emerged by the analysis, which were used to reconstruct the original muscle activations. It was showed that four and six muscle synergies were adequate to reconstruct the input data of 2-D and 3-D torque space analysis. The synergies were different by choosing alternative cost functions as expected. The constraints affected the extracted muscle synergies, particularly muscles that participated in more than one functional tasks were influenced substantially. The compositions of extracted muscle synergies were in agreement with experimental studies on healthy participants. The following computational methods show that the synergies can reduce the complexity of load distributions and allow reduced dimensional space to be used in clinical settings.

  11. Effect of echo contrast media on the visualization of transverse sinus thrombosis with transcranial 3-D duplex sonography.

    PubMed

    Delcker, A; Häussermann, P; Weimar, C

    1999-09-01

    Transcranial duplex sonography has the capacity of detecting venous flow as in the transverse sinus. During a 6-month period, 28 consecutive patients (mean age 55 y) with a clinically suspected diagnosis of cerebral sinus thrombosis were included in the study. All patients were examined using 3-D ultrasound equipment within 24 h of having undergone either venous computerized tomography (CT), venous magnetic resonance imaging (MRI) or cerebral angiography. A total of 22 healthy patients had a normal venous CT, venous MRI or cerebral angiography of both transverse sinuses. Before echo contrast enhancement, the transverse sinus could be visualized in only 2 of these 44 sinuses (22 patients). A total of 6 patients with an unilaterally missed transverse sinus in 3-D ultrasound suffered from sinus thrombosis (n = 3), hypoplasia (n = 2) or aplasia (n = 1) of the unilateral transverse sinus in neuroradiological tests. In none of the patients with an thrombosis of the transverse sinus did ultrasound contrast media application improve the visualization of the affected sinus. Our study confirms that the normal transverse sinus, insonated through the contralateral temporal bone, often cannot be visualized without the use of contrast agents. With transcranial 3-D duplex sonography, a differentiation between thrombosis, hypoplasia and aplasia of the sinus was not possible.

  12. Chirality effect on nearly half-metallic properties in systematic endo-doping of 3d transition metals of narrow carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Malehmir, M.; Khoshnevisan, B.

    2016-10-01

    Spin polarized density functional calculations were employed to study chirality effect on electronic and magnetic properties of 3d transition metals (TMs) endo-doped co-diameter (∼7 Å) narrow (5,5) and (9,0) single walled carbon nanotubes (CNTs). Various magnetizations up to ∼6μB was obtained for different 3dTM-CNT systems (recall that the magnetization of fcc structure cobalt is ∼1.6μB). In addition nearly half-metallic magnetic behavior has been observed for the most of considered systems. These results would be useful for spintronic and nano-magnetic technology.

  13. Jovian Plasmas Torus Interaction with Europa. Plasma Wake Structure and Effect of Inductive Magnetic Field: 3D Hybrid Kinetic Simulation

    NASA Technical Reports Server (NTRS)

    Lipatov, A. S.; Cooper, J F.; Paterson, W. R.; Sittler, E. C., Jr.; Hartle, R. E.; Simpson, David G.

    2013-01-01

    The hybrid kinetic model supports comprehensive simulation of the interaction between different spatial and energetic elements of the Europa moon-magnetosphere system with respect to a variable upstream magnetic field and flux or density distributions of plasma and energetic ions, electrons, and neutral atoms. This capability is critical for improving the interpretation of the existing Europa flyby measurements from the Galileo Orbiter mission, and for planning flyby and orbital measurements (including the surface and atmospheric compositions) for future missions. The simulations are based on recent models of the atmosphere of Europa (Cassidy et al., 2007; Shematovich et al., 2005). In contrast to previous approaches with MHD simulations, the hybrid model allows us to fully take into account the finite gyroradius effect and electron pressure, and to correctly estimate the ion velocity distribution and the fluxes along the magnetic field (assuming an initial Maxwellian velocity distribution for upstream background ions). Photoionization, electron-impact ionization, charge exchange and collisions between the ions and neutrals are also included in our model. We consider the models with Oþ þ and Sþ þ background plasma, and various betas for background ions and electrons, and pickup electrons. The majority of O2 atmosphere is thermal with an extended non-thermal population (Cassidy et al., 2007). In this paper, we discuss two tasks: (1) the plasma wake structure dependence on the parameters of the upstream plasma and Europa's atmosphere (model I, cases (a) and (b) with a homogeneous Jovian magnetosphere field, an inductive magnetic dipole and high oceanic shell conductivity); and (2) estimation of the possible effect of an induced magnetic field arising from oceanic shell conductivity. This effect was estimated based on the difference between the observed and modeled magnetic fields (model II, case (c) with an inhomogeneous Jovian magnetosphere field, an inductive

  14. 3D Cloud Radiative Effects on Aerosol Optical Thickness Retrievals in Cumulus Cloud Fields in the Biomass Burning Region in Brazil

    NASA Technical Reports Server (NTRS)

    Wen, Guo-Yong; Marshak, Alexander; Cahalan, Robert F.

    2004-01-01

    Aerosol amount in clear regions of a cloudy atmosphere is a critical parameter in studying the interaction between aerosols and clouds. Since the global cloud cover is about 50%, cloudy scenes are often encountered in any satellite images. Aerosols are more or less transparent, while clouds are extremely reflective in the visible spectrum of solar radiation. The radiative transfer in clear-cloudy condition is highly three- dimensional (3D). This paper focuses on estimating the 3D effects on aerosol optical thickness retrievals using Monte Carlo simulations. An ASTER image of cumulus cloud fields in the biomass burning region in Brazil is simulated in this study. The MODIS products (i-e., cloud optical thickness, particle effective radius, cloud top pressure, surface reflectance, etc.) are used to construct the cloud property and surface reflectance fields. To estimate the cloud 3-D effects, we assume a plane-parallel stratification of aerosol properties in the 60 km x 60 km ASTER image. The simulated solar radiation at the top of the atmosphere is compared with plane-parallel calculations. Furthermore, the 3D cloud radiative effects on aerosol optical thickness retrieval are estimated.

  15. Effects of Type of Exploratory Strategy and Prior Knowledge on Middle School Students' Learning of Chemical Formulas from a 3D Role-Playing Game

    ERIC Educational Resources Information Center

    Chen, Ming-Puu; Wong, Yu-Ting; Wang, Li-Chun

    2014-01-01

    The purpose of this study was to examine the effects of the type of exploratory strategy and level of prior knowledge on middle school students' performance and motivation in learning chemical formulas via a 3D role-playing game (RPG). Two types of exploratory strategies-RPG exploratory with worked-example and RPG exploratory without…

  16. Effects of Spatial Ability, Gender Differences, and Pictorial Training on Children Using 2-D and 3-D Environments to Recall Landmark Locations from Memory

    ERIC Educational Resources Information Center

    Kopcha, Theodore J.; Otumfuor, Beryl A.; Wang, Lu

    2015-01-01

    This study examines the effects of spatial ability, gender differences, and pictorial training on fourth grade students' ability to recall landmark locations from memory. Ninety-six students used Google Earth over a 3-week period to locate landmarks (3-D) and mark their location on a 2-D topographical map. Analysis of covariance on posttest scores…

  17. An Examination of the Effects of Collaborative Scientific Visualization via Model-Based Reasoning on Science, Technology, Engineering, and Mathematics (STEM) Learning within an Immersive 3D World

    ERIC Educational Resources Information Center

    Soleimani, Ali

    2013-01-01

    Immersive 3D worlds can be designed to effectively engage students in peer-to-peer collaborative learning activities, supported by scientific visualization, to help with understanding complex concepts associated with learning science, technology, engineering, and mathematics (STEM). Previous research studies have shown STEM learning benefits…

  18. 3D modeling of effects of increased oxygenation and activity concentration in tumors treated with radionuclides and antiangiogenic drugs

    SciTech Connect

    Lagerloef, Jakob H.; Kindblom, Jon; Bernhardt, Peter

    2011-08-15

    Purpose: Formation of new blood vessels (angiogenesis) in response to hypoxia is a fundamental event in the process of tumor growth and metastatic dissemination. However, abnormalities in tumor neovasculature often induce increased interstitial pressure (IP) and further reduce oxygenation (pO{sub 2}) of tumor cells. In radiotherapy, well-oxygenated tumors favor treatment. Antiangiogenic drugs may lower IP in the tumor, improving perfusion, pO{sub 2} and drug uptake, by reducing the number of malfunctioning vessels in the tissue. This study aims to create a model for quantifying the effects of altered pO{sub 2}-distribution due to antiangiogenic treatment in combination with radionuclide therapy. Methods: Based on experimental data, describing the effects of antiangiogenic agents on oxygenation of GlioblastomaMultiforme (GBM), a single cell based 3D model, including 10{sup 10} tumor cells, was developed, showing how radionuclide therapy response improves as tumor oxygenation approaches normal tissue levels. The nuclides studied were {sup 90}Y, {sup 131}I, {sup 177}Lu, and {sup 211}At. The absorbed dose levels required for a tumor control probability (TCP) of 0.990 are compared for three different log-normal pO{sub 2}-distributions: {mu}{sub 1} = 2.483, {sigma}{sub 1} = 0.711; {mu}{sub 2} = 2.946, {sigma}{sub 2} = 0.689; {mu}{sub 3} = 3.689, and {sigma}{sub 3} = 0.330. The normal tissue absorbed doses will, in turn, depend on this. These distributions were chosen to represent the expected oxygen levels in an untreated hypoxic tumor, a hypoxic tumor treated with an anti-VEGF agent, and in normal, fully-oxygenated tissue, respectively. The former two are fitted to experimental data. The geometric oxygen distributions are simulated using two different patterns: one Monte Carlo based and one radially increasing, while keeping the log-normal volumetric distributions intact. Oxygen and activity are distributed, according to the same pattern. Results: As tumor pO{sub 2

  19. Origin of enhanced visible-light photocatalytic activity of transition-metal (Fe, Cr and Co)-doped CeO2: effect of 3 d orbital splitting

    NASA Astrophysics Data System (ADS)

    Yang, Ke; Li, Dong-Feng; Huang, Wei-Qing; Xu, Liang; Huang, Gui-Fang; Wen, Shuangchun

    2017-01-01

    Enhanced visible-light photocatalytic activity of transition-metal-doped ceria (CeO2) nanomaterials has experimentally been demonstrated, whereas there are very few reports mentioning the mechanism of this behavior. Here, we use first-principles calculations to explore the origin of enhanced photocatalytic performance of CeO2 doped with transition metal impurities (Fe, Cr and Co). When a transition metal atom substitutes a Ce atom into CeO2, t 2g and e g levels of 3 d orbits appear in the middle of band gap owing to the effect of cubic ligand field, and the former is higher than latter. Interestingly, t 2g subset of FeCe (CoCe and CrCe)-Vo-CeO2 splits into two parts: one merges into the conduction band, the other as well as e g will remain in the gap, because O vacancy defect adjacent to transition metal atom will break the symmetry of cubic ligand field. These e g and t 2g levels in the band gap are beneficial for absorbing visible-light and enhancing quantum efficiency because of forbidden transition, which is one key factor for enhanced visible-light photocatalytic activity. The band gap narrowing also leads to a redshift of optical absorbance and high photoactivity. These findings can rationalize the available experimental results and provide some new insights for designing CeO2-based photocatalysts with high photocatalytic performance.

  20. Slope instability in complex 3D topography promoted by convergent 3D groundwater flow

    NASA Astrophysics Data System (ADS)

    Reid, M. E.; Brien, D. L.

    2012-12-01

    headlands and re-entrants to minimize slope effects on stability. Despite these equal slopes, our analyses, given dry conditions, illustrated that the headlands can be 5-7% less stable than the re-entrants, owing to the geometry of the 3D failure mass with the lowest stability. We then simulated groundwater flow in these landscapes; flow was caused by recharge perching on a horizontal low permeability layer with discharge at the bluff faces. By systematically varying recharge, hydraulic conductivity of the material, and conductance at the bluffs, we created different 3D pore-pressure fields. Recharge rates and hydraulic conductivities controlled the height of the water table, whereas bluff conductance influenced the gradient of the water table near the bluff face. Given elevated water tables with steep gradients, bluffs in the re-entrants became unstable where flow converged. Thus, with progressively stronger effects from water flow, overall instability evolved from relatively unstable headlands to more uniform stability to relatively unstable re-entrants. Larger re-entrants led to more 3D flow convergence and greater localized instability. One- or two-dimensional models cannot fully characterize slope instability in complex topography.

  1. Analysis and modeling of photomask edge effects for 3D geometries and the effect on process window

    NASA Astrophysics Data System (ADS)

    Miller, Marshal A.; Neureuther, Andrew R.

    2009-03-01

    Simulation was used to explore boundary layer models for 1D and 2D patterns that would be appropriate for fast CAD modeling of physical effects during design. FDTD simulation was used to compare rigorous thick mask modeling to a thin mask approximation (TMA). When features are large, edges can be viewed as independent and modeled as separate from one another, but for small mask features, edges experience cross-talk. For attenuating phase-shift masks, interaction distances as large as 150nm were observed. Polarization effects are important for accurate EMF models. Due to polarization effects, the edge perturbations in line ends become different compared to a perpendicular edge. For a mask designed to be real, the 90o transmission created at edges produces an asymmetry through focus, which is also polarization dependent. Thick mask fields are calculated using TEMPEST and Panoramic Technologies software. Fields are then analyzed in the near field and on wafer CDs to examine deviations from TMA.

  2. PCaAnalyser: A 2D-Image Analysis Based Module for Effective Determination of Prostate Cancer Progression in 3D Culture

    PubMed Central

    Lovitt, Carrie J.; Avery, Vicky M.

    2013-01-01

    Three-dimensional (3D) in vitro cell based assays for Prostate Cancer (PCa) research are rapidly becoming the preferred alternative to that of conventional 2D monolayer cultures. 3D assays more precisely mimic the microenvironment found in vivo, and thus are ideally suited to evaluate compounds and their suitability for progression in the drug discovery pipeline. To achieve the desired high throughput needed for most screening programs, automated quantification of 3D cultures is required. Towards this end, this paper reports on the development of a prototype analysis module for an automated high-content-analysis (HCA) system, which allows for accurate and fast investigation of in vitro 3D cell culture models for PCa. The Java based program, which we have named PCaAnalyser, uses novel algorithms that allow accurate and rapid quantitation of protein expression in 3D cell culture. As currently configured, the PCaAnalyser can quantify a range of biological parameters including: nuclei-count, nuclei-spheroid membership prediction, various function based classification of peripheral and non-peripheral areas to measure expression of biomarkers and protein constituents known to be associated with PCa progression, as well as defining segregate cellular-objects effectively for a range of signal-to-noise ratios. In addition, PCaAnalyser architecture is highly flexible, operating as a single independent analysis, as well as in batch mode; essential for High-Throughput-Screening (HTS). Utilising the PCaAnalyser, accurate and rapid analysis in an automated high throughput manner is provided, and reproducible analysis of the distribution and intensity of well-established markers associated with PCa progression in a range of metastatic PCa cell-lines (DU145 and PC3) in a 3D model demonstrated. PMID:24278197

  3. Effect of bioink properties on printability and cell viability for 3D bioplotting of embryonic stem cells.

    PubMed

    Ouyang, Liliang; Yao, Rui; Zhao, Yu; Sun, Wei

    2016-09-16

    3D cell printing is an emerging technology for fabricating complex cell-laden constructs with precise and pre-designed geometry, structure and composition to overcome the limitations of 2D cell culture and conventional tissue engineering scaffold technology. This technology enables spatial manipulation of cells and biomaterials, also referred to as 'bioink', and thus allows study of cellular interactions in a 3D microenvironment and/or in the formation of functional tissues and organs. Recently, many efforts have been made to develop new bioinks and to apply more cell sources for better biocompatibility and biofunctionality. However, the influences of printing parameters on the shape fidelity of 3D constructs as well as on cell viability after the cell printing process have been poorly characterized. Furthermore, parameter optimization based on a specific cell type might not be suitable for other types of cells, especially cells with high sensibility. In this study, we systematically studied the influence of bioink properties and printing parameters on bioink printability and embryonic stem cell (ESC) viability in the process of extrusion-based cell printing, also known as bioplotting. A novel method was established to determine suitable conditions for bioplotting ESCs to achieve both good printability and high cell viability. The rheological properties of gelatin/alginate bioinks were evaluated to determine the gelation properties under different bioink compositions, printing temperatures and holding times. The bioink printability was characterized by a newly developed semi-quantitative method. The results demonstrated that bioinks with longer gelation times would result in poorer printability. The live/dead assay showed that ESC viability increased with higher printing temperatures and lower gelatin concentrations. Furthermore, an exponential relationship was obtained between ESC viability and induced shear stress. By defining the proper printability and

  4. The Effect of Lutein Supplementation on Blood Plasma Levels of Complement Factor D, C5a and C3d

    PubMed Central

    Tian, Yuan; Kijlstra, Aize; van der Veen, Rob L. P.; Makridaki, Maria; Murray, Ian J.; Berendschot, Tos T. J. M.

    2013-01-01

    Lutein is selectively taken up by the primate retina and plays an important role as a filter for harmful blue light and as an antioxidant. Recent studies have shown that lutein has systemic anti-inflammatory properties. Dietary lutein has been associated with reduced circulating levels of inflammatory biomarkers such as CRP and sICAM. Whether lutein also affects activation of the complement system has not yet been addressed and was the purpose of the study described here. Seventy-two subjects with signs of early macular degeneration were randomly assigned to receive either a 10 mg lutein supplement or a placebo during one year. EDTA blood samples were collected at 0, 4, 8 and 12 months. Complement factor D (CFD), a rate limiting component of the alternative pathway of complement activation and the complement activation products C5a and C3d were determined in the plasma samples by ELISA. A significant 0.11 µg/ml monthly decrease in plasma CFD concentration was observed in the lutein group (p<0.001), resulting in a 51% decrease from 2.3 µg/ml at baseline to 1.0 µg/ml at 12 months. The C5a concentration showed a significant 0.063ng/ml monthly decrease in the lutein group (p<0.001) resulting in a 36% decrease from 2.2ng/ml at baseline to 1.6ng/ml at 12 months. The C3d concentration showed a significant 0.19µg/ml monthly decrease in the lutein group (p=0.004) that gave rise to a 9% decrease from 15.4µg/ml at baseline to 14.4µg/ml at 12 months. In the placebo group we found a significant 0.04 µg/ml monthly decrease in plasma CFD concentration, whereas no changes were observed for C5a and C3d. Lutein supplementation markedly decreases circulating levels of the complement factors CFD, C5a and C3d levels, which might allow a simple method to control this inflammatory pathway of the innate immune system. PMID:24009749

  5. Effect of 3-D instrument casing shape on the self-shading of in-water upwelling irradiance.

    PubMed

    Piskozub, Jacek

    2004-07-12

    The self-shading measurement error of the upwelling irradiance caused by the presence of a typical cylindrical housing of an optical instrument was calculated with the 3-D Monte-Carlo code as a function of the housing dimensions and of the optical parameters of seawater. The resulting values were compared to the self-shading error for a flat disk of the same diameter, originally used to establish self-shading error estimations universally used in marine optics. The results show that the self-shading of upwelling irradiance is underestimated by up to 25% producing a significant underestimation of the measured upwelling irradiance, and therefore reflectance, especially in turbid waters.

  6. Effect of 3-D instrument casing shape on the self-shading of in-water upwelling irradiance

    NASA Astrophysics Data System (ADS)

    Piskozub, Jacek

    2004-07-01

    The self-shading measurement error of the upwelling irradiance caused by the presence of a typical cylindrical housing of an optical instrument was calculated with the 3-D Monte-Carlo code as a function of the housing dimensions and of the optical parameters of seawater. The resulting values were compared to the self-shading error for a flat disk of the same diameter, originally used to establish self-shading error estimations universally used in marine optics. The results show that the self-shading of upwelling irradiance is underestimated by up to 25% producing a significant underestimation of the measured upwelling irradiance, and therefore reflectance, especially in turbid waters.

  7. Is principal component analysis an effective tool to predict face attractiveness? A contribution based on real 3D faces of highly selected attractive women, scanned with stereophotogrammetry.

    PubMed

    Galantucci, Luigi Maria; Di Gioia, Eliana; Lavecchia, Fulvio; Percoco, Gianluca

    2014-05-01

    In the literature, several papers report studies on mathematical models used to describe facial features and to predict female facial beauty based on 3D human face data. Many authors have proposed the principal component analysis (PCA) method that permits modeling of the entire human face using a limited number of parameters. In some cases, these models have been correlated with beauty classifications, obtaining good attractiveness predictability using wrapped 2D or 3D models. To verify these results, in this paper, the authors conducted a three-dimensional digitization study of 66 very attractive female subjects using a computerized noninvasive tool known as 3D digital photogrammetry. The sample consisted of the 64 contestants of the final phase of the Miss Italy 2010 beauty contest, plus the two highest ranked contestants in the 2009 competition. PCA was conducted on this real faces sample to verify if there is a correlation between ranking and the principal components of the face models. There was no correlation and therefore, this hypothesis is not confirmed for our sample. Considering that the results of the contest are not only solely a function of facial attractiveness, but undoubtedly are significantly impacted by it, the authors based on their experience and real faces conclude that PCA analysis is not a valid prediction tool for attractiveness. The database of the features belonging to the sample analyzed are downloadable online and further contributions are welcome.

  8. Differential effects of MAPK pathway inhibitors on migration and invasiveness of BRAF(V600E) mutant thyroid cancer cells in 2D and 3D culture.

    PubMed

    Ingeson-Carlsson, Camilla; Martinez-Monleon, Angela; Nilsson, Mikael

    2015-11-01

    Tumor microenvironment influences targeted drug therapy. In this study we compared drug responses to RAF and MEK inhibitors on tumor cell migration in 2D and 3D culture of BRAF(V600E) mutant cell lines derived from human papillary (BCPAP) and anaplastic (SW1736) thyroid carcinomas. Scratch wounding was compared to a double-layered collagen gel model developed for analysis of directed tumor cell invasion during prolonged culture. In BCPAP both PLX4720 and U0126 inhibited growth and migration in 2D and decreased tumor cell survival in 3D. In SW1736 drugs had no effect on migration in 2D but decreased invasion in 3D, however this related to reduced growth. Dual inhibition of BRAF(V600E) and MEK reduced but did not prevent SW1736 invasion although rebound phosphorylation of ERK in response to PLX4720 was blocked by U0126. These findings indicate that anti-tumor drug effects in vitro differ depending on culture conditions (2D vs. 3D) and that the invasive features of anaplastic thyroid cancer depend on non-MEK mechanism(s).

  9. Toward a 3D cellular model for studying in vitro the outcome of photodynamic treatments: accounting for the effects of tissue complexity.

    PubMed

    Alemany-Ribes, Mireia; García-Díaz, María; Busom, Marta; Nonell, Santi; Semino, Carlos E

    2013-08-01

    Clinical therapies have traditionally been developed using two-dimensional (2D) cell culture systems, which fail to accurately capture tissue complexity. Therefore, three-dimensional (3D) cell cultures are more attractive platforms to integrate multiple cues that arise from the extracellular matrix and cells, closer to an in vivo scenario. Here we report the development of a 3D cellular model for the in vitro assessment of the outcome of oxygen- and drug-dependent therapies, exemplified by photodynamic therapy (PDT). Using a synthetic self-assembling peptide as a cellular scaffold (RAD16-I), we were able to recreate the in vivo limitation of oxygen and drug diffusion and its biological effect, which is the development of cellular resistance to therapy. For the first time, the production and decay of the cytotoxic species singlet oxygen could be observed in a 3D cell culture. Results revealed that the intrinsic mechanism of action is maintained in both systems and, hence, the dynamic mass transfer effects accounted for the major differences in efficacy between the 2D and 3D models. We propose that this methodological approach will help to improve the efficacy of future oxygen- and drug-dependent therapies such as PDT.

  10. A 3D model of tumour angiogenic microenvironment to monitor hypoxia effects on cell interactions and cancer stem cell selection.

    PubMed

    Klimkiewicz, Krzysztof; Weglarczyk, Kazimierz; Collet, Guillaume; Paprocka, Maria; Guichard, Alan; Sarna, Michal; Jozkowicz, Alicja; Dulak, Jozef; Sarna, Tadeusz; Grillon, Catherine; Kieda, Claudine

    2017-03-10

    Tumour microenvironment determines the fate of treatments. Reconstitution of tumour conditions is mandatory for alternative in vitro methods devoted to cancer development and the selection of therapeutic strategies. This work describes a 3D model of melanoma growth in its environment. Introducing means to mimic tumour angiogenesis, which turns on tumour progression, the model shows that melanoma tumour spheroids allow reconstitution of solid tumours with stromal cells. Angiogenesis evidenced the differential recruitment of endothelial cells (EC) from early progenitors (EEPCs) to mature ECs. Hypoxia was the key parameter that selected and stabilized melanoma cancer stem like cells (CSCs) phenotype based on aldehyde dehydrogenase expression as the best criterion. The 3D-tumour-model demonstrated the distinct reactivity of ECs toward tumour cells in terms of cellular cross-talk and humoral response. Intra-spheroid cell-to-cell membrane dye exchanges, mediated by intercellular interactions, uncovered the melanoma-to-EEPC cooperation. The resulting changes in tumour milieu were evidenced by the chemokinic composition and hypoxia-related variations in microRNA expression assessed in each cellular component of the spheroids. This method brings new tools to decipher the molecular mechanism of tumour-mediated cell recruitment and for in vitro assessment of therapeutic approaches.

  11. Copper and cadmium effects on growth and extracellular exudation of the marine toxic dinoflagellate Alexandrium catenella: 3D-fluorescence spectroscopy approach.

    PubMed

    Herzi, Faouzi; Jean, Natacha; Zhao, Huiyu; Mounier, Stéphane; Mabrouk, Hassine Hadj; Hlaili, Asma Sakka

    2013-10-01

    In this study, metal contamination experiments were conducted to investigate the effects of copper and cadmium on the growth of the marine toxic dinoflagellate Alexandrium catenella and on the production of dissolved organic matter (Dissolved Organic Carbon: DOC; Fluorescent Dissolved Organic Matter: FDOM). This species was exposed to increasing concentrations of Cu(2+) (9.93 × 10(-10)-1.00 × 10(-7)M) or Cd(2+) (1.30 × 10(-8)-4.38 × 10(-7)M), to simulate polluted environments. The drastic effects were observed at pCu(2+)=7.96 (Cu(2+): 1.08 × 10(-8)M) and pCd(2+)=7.28 (Cd(2+): 5.19 × 10(-8)M), where cyst formation occurred. Lower levels of Cu(2+) (pCu(2+)>9.00) and Cd(2+) (pCd(2+)>7.28) had no effect on growth. However, when levels of Cu(2+) and Cd(2+) were beyond 10(-7)M, the growth was totally inhibited. The DOC released per cell (DOC/Cell) was different depending on the exposure time and the metal contamination, with higher DOC/Cell values in response to Cu(2+) and Cd(2+), comparatively to the control. Samples were also analyzed by 3D-fluorescence spectroscopy, using the Parallel Factor Analysis (PARAFAC) algorithm to characterize the FDOM. The PARAFAC analytical treatment revealed four components (C1, C2, C3 and C4) that could be associated with two contributions: one, related to the biological activity; the other, linked to the decomposition of organic matter. The C1 component combined a tryptophan peak and a characteristic humic substances response, and the C2 component was considered as a tryptophan protein fluorophore. The C3 and C4 components were associated to marine organic matter production.

  12. Frequency-dependent effective hydraulic conductivity of strongly heterogeneous media.

    PubMed

    Caspari, E; Gurevich, B; Müller, T M

    2013-10-01

    The determination of the transport properties of heterogeneous porous rocks, such as an effective hydraulic conductivity, arises in a range of geoscience problems, from groundwater flow analysis to hydrocarbon reservoir modeling. In the presence of formation-scale heterogeneities, nonstationary flows, induced by pumping tests or propagating elastic waves, entail localized pressure diffusion processes with a characteristic frequency depending on the pressure diffusivity and size of the heterogeneity. Then, on a macroscale, a homogeneous equivalent medium exists, which has a frequency-dependent effective conductivity. The frequency dependence of the conductivity can be analyzed with Biot's equations of poroelasticity. In the quasistatic frequency regime of this framework, the slow compressional wave is a proxy for pressure diffusion processes. This slow compressional wave is associated with the out-of-phase motion of the fluid and solid phase, thereby creating a relative fluid-solid displacement vector field. Decoupling of the poroelasticity equations gives a diffusion equation for the fluid-solid displacement field valid in a poroelastic medium with spatial fluctuations in hydraulic conductivity. Then, an effective conductivity is found by a Green's function approach followed by a strong-contrast perturbation theory suggested earlier in the context of random dielectrics. This theory leads to closed-form expressions for the frequency-dependent effective conductivity as a function of the one- and two-point probability functions of the conductivity fluctuations. In one dimension, these expressions are consistent with exact solutions in both low- and high-frequency limits for arbitrary conductivity contrast. In 3D, the low-frequency limit depends on the details of the microstructure. However, the derived approximation for the effective conductivity is consistent with the Hashin-Shtrikman bounds.

  13. Twin Peaks - 3D

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The two hills in the distance, approximately one to two kilometers away, have been dubbed the 'Twin Peaks' and are of great interest to Pathfinder scientists as objects of future study. 3D glasses are necessary to identify surface detail. The white areas on the left hill, called the 'Ski Run' by scientists, may have been formed by hydrologic processes.

    The IMP is a stereo imaging system with color capability provided by 24 selectable filters -- twelve filters per 'eye.

    Click below to see the left and right views individually. [figure removed for brevity, see original site] Left [figure removed for brevity, see original site] Right

  14. 3D and beyond

    NASA Astrophysics Data System (ADS)

    Fung, Y. C.

    1995-05-01

    This conference on physiology and function covers a wide range of subjects, including the vasculature and blood flow, the flow of gas, water, and blood in the lung, the neurological structure and function, the modeling, and the motion and mechanics of organs. Many technologies are discussed. I believe that the list would include a robotic photographer, to hold the optical equipment in a precisely controlled way to obtain the images for the user. Why are 3D images needed? They are to achieve certain objectives through measurements of some objects. For example, in order to improve performance in sports or beauty of a person, we measure the form, dimensions, appearance, and movements.

  15. 3D Audio System

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Ames Research Center research into virtual reality led to the development of the Convolvotron, a high speed digital audio processing system that delivers three-dimensional sound over headphones. It consists of a two-card set designed for use with a personal computer. The Convolvotron's primary application is presentation of 3D audio signals over headphones. Four independent sound sources are filtered with large time-varying filters that compensate for motion. The perceived location of the sound remains constant. Possible applications are in air traffic control towers or airplane cockpits, hearing and perception research and virtual reality development.

  16. Effects of the LBV Primary's Mass-loss Rate on the 3D Hydrodynamics of eta Carinae's Colliding Winds

    NASA Technical Reports Server (NTRS)

    Madura, Thomas I.; Gull, Theodore R.; Cocoran, M.; Okazaki, A.; Owocki, S.; Russell, C.; Hamaguchi, K.; Clementel, N; Groh, J.; Hillier, D. J.

    2013-01-01

    At the heart of eta Carinae's spectacular "Homunculus" nebula lies an extremely luminous (L(sub Total) greater than approximately 5 × 10(exp 6) solar luminosity) colliding wind binary with a highly eccentric (e approximately 0.9), 5.54-year orbit (Figure 1). The primary of the system, a Luminous Blue Variable (LBV), is our closest (D approximately 2.3 kpc) and best example of a pre-hypernova or pre-gamma ray burst environment. The remarkably consistent and periodic RXTE X-ray light curve surprisingly showed a major change during the system's last periastron in 2009, with the X-ray minimum being approximately 50% shorter than the minima of the previous two cycles1. Between 1998 and 2011, the strengths of various broad stellar wind emission lines (e.g. Halpha, Fe II) in line-of-sight (l.o.s.) also decreased by factors of 1.5 - 3 relative to the continuum2. The current interpretation for these changes is that they are due to a gradual factor of 2 - 4 drop in the primary's mass-loss rate over the last approximately 15 years1, 2. However, while a secular change is seen for a direct view of the central source, little to no change is seen in profiles at high stellar latitudes or reflected off of the dense, circumbinary material known as the "Weigelt blobs"2, 3. Moreover, model spectra generated with CMFGEN predict that a factor of 2 - 4 drop in the primary's mass-loss rate should lead to huge changes in the observed spectrum, which thus far have not been seen. Here we present results from large- (plus or minus 1620 AU) and small- (plus or minus 162 AU) domain, full 3D smoothed particle hydrodynamics (SPH) simulations of eta Car's massive binary colliding winds for three different primary-star mass-loss rates (2.4, 4.8, and 8.5 × 10(exp -4) solar mass/yr). The goal is to investigate how the mass-loss rate affects the 3D geometry and dynamics of eta Car's optically-thick wind and spatially-extended wind-wind collision (WWC) regions, both of which are known sources of

  17. The effect of CT scanner parameters and 3D volume rendering techniques on the accuracy of linear, angular, and volumetric measurements of the mandible

    PubMed Central

    Whyms, B.J.; Vorperian, H.K.; Gentry, L.R.; Schimek, E.M.; Bersu, E.T.; Chung, M.K.

    2013-01-01

    Objectives This study investigates the effect of scanning parameters on the accuracy of measurements from three-dimensional multi-detector computed tomography (3D-CT) mandible renderings. A broader range of acceptable parameters can increase the availability of CT studies for retrospective analysis. Study Design Three human mandibles and a phantom object were scanned using 18 combinations of slice thickness, field of view, and reconstruction algorithm and three different threshold-based segmentations. Measurements of 3D-CT models and specimens were compared. Results Linear and angular measurements were accurate, irrespective of scanner parameters or rendering technique. Volume measurements were accurate with a slice thickness of 1.25 mm, but not 2.5 mm. Surface area measurements were consistently inflated. Conclusions Linear, angular and volumetric measurements of mandible 3D-CT models can be confidently obtained from a range of parameters and rendering techniques. Slice thickness is the primary factor affecting volume measurements. These findings should also apply to 3D rendering using cone-beam-CT. PMID:23601224

  18. Effects of oxygen vacancy on 3d transition-metal doped anatase TiO2: First principles calculations

    NASA Astrophysics Data System (ADS)

    Zhao, Ya Fei; Li, Can; Lu, Song; Yan, Li Jin; Gong, Yin Yan; Niu, Leng Yuan; Liu, Xin Juan

    2016-03-01

    In this work, systematic study of the formation energy, crystalline and electronic structures of 3d transition metal (Sc, V, Cr, Mn, Fe, Co and Ni) doped anatase TiO2 specimens with and without oxygen vacancy has been carried out by the first principles calculations. The impurity states located at the band gaps enhance the visible light absorption, and the oxygen vacancy result in the EF move into the CB for some doped systems, which induce the Ti3+ ions and promote the separation of photogenerated carriers. Doping and oxygen vacancy can change the hybrid strength and MP value of TMsbnd O bonding which has the approximately linearly with the band gap.

  19. 3D Surgical Simulation

    PubMed Central

    Cevidanes, Lucia; Tucker, Scott; Styner, Martin; Kim, Hyungmin; Chapuis, Jonas; Reyes, Mauricio; Proffit, William; Turvey, Timothy; Jaskolka, Michael

    2009-01-01

    This paper discusses the development of methods for computer-aided jaw surgery. Computer-aided jaw surgery allows us to incorporate the high level of precision necessary for transferring virtual plans into the operating room. We also present a complete computer-aided surgery (CAS) system developed in close collaboration with surgeons. Surgery planning and simulation include construction of 3D surface models from Cone-beam CT (CBCT), dynamic cephalometry, semi-automatic mirroring, interactive cutting of bone and bony segment repositioning. A virtual setup can be used to manufacture positioning splints for intra-operative guidance. The system provides further intra-operative assistance with the help of a computer display showing jaw positions and 3D positioning guides updated in real-time during the surgical procedure. The CAS system aids in dealing with complex cases with benefits for the patient, with surgical practice, and for orthodontic finishing. Advanced software tools for diagnosis and treatment planning allow preparation of detailed operative plans, osteotomy repositioning, bone reconstructions, surgical resident training and assessing the difficulties of the surgical procedures prior to the surgery. CAS has the potential to make the elaboration of the surgical plan a more flexible process, increase the level of detail and accuracy of the plan, yield higher operative precision and control, and enhance documentation of cases. Supported by NIDCR DE017727, and DE018962 PMID:20816308

  20. Martian terrain - 3D

    NASA Technical Reports Server (NTRS)

    1997-01-01

    An area of rocky terrain near the landing site of the Sagan Memorial Station can be seen in this image, taken in stereo by the Imager for Mars Pathfinder (IMP) on Sol 3. 3D glasses are necessary to identify surface detail. This image is part of a 3D 'monster' panorama of the area surrounding the landing site.

    Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

    Click below to see the left and right views individually. [figure removed for brevity, see original site] Left [figure removed for brevity, see original site] Right

  1. Effect of fibre posts, bone losses and fibre content on the biomechanical behaviour of endodontically treated teeth: 3D-finite element analysis.

    PubMed

    Chieruzzi, Manila; Pagano, Stefano; Cianetti, Stefano; Lombardo, Guido; Kenny, José M; Torre, Luigi

    2017-05-01

    The aim of this work was to evaluate the stress distribution inside endodontically treated teeth restored with different posts (glass fibre, carbon fibre and steel posts) under different loading conditions by using a 3D-finite element analysis. The effect of masticatory and impact forces on teeth with different degrees of bone loss was analysed. The model consists of: dentine, post, cement, gutta-percha, core and crown. Four simulations were conducted with two static forces (170N horizontal and 100N oblique) and two sections constrained: 1mm (alveolar bone position in a normal periodontium) and 6mm (middle of root) below the crown. Von Mises and the principal stresses were evaluated and analysed with a 3-way ANOVA and Tukey test (α=0.05) and the effect of fibre percentage analysed. Significant differences were found among the stress values for all conditions (p<0.05). Impact load was always responsible for the most critical situation especially when the bone loss was more evident. The system with steel posts showed the highest principal stresses at the post-cement interface with horizontal load and top constraints (compressive stress of 121MPa and tensile stress of 115MPa). The use of glass posts provides a more homogeneous behaviour of the system with lower stresses. Higher fibre percentages gave higher stress in the posts. Moreover, larger bone losses are responsible for important increase in stress. Thus, this work demonstrated that periodontal disease has an important role in the success of tooth restoration after endodontic therapy, influencing the choice of post material and depth.

  2. A 3D POM-MOF composite based on Ni(ΙΙ) ion and 2,2‧-bipyridyl-3,3‧-dicarboxylic acid: Crystal structure and proton conductivity

    NASA Astrophysics Data System (ADS)

    Wei, Meilin; Wang, Xiaoxiang; Sun, Jingjing; Duan, Xianying

    2013-06-01

    We have succeeded in constructing a 3D POM-MOF, {H[Ni(Hbpdc)(H2O)2]2[PW12O40]·8H2O}n (H2bpdc=2,2'-bipyridyl-3,3'-dicarboxylic acid), by the controllable self-assembly of H2bpdc, Keggin-anions and Ni2+ ions based on the electrostatic and coordination interactions. Interestingly, Hbpdc- as polydentate organic ligands and Keggin-anion as polydentate inorganic ligands are covalently linked transition-metal nickel at the same time. The title complex represents a new example of introducing the metal N-heterocyclic multi-carboxylic acid frameworks into POMs chemistry. Based on Keggin-anions being immobilized as part of the metal N-heterocyclic multi-carboxylic acid framework, the title complex realizes four approaches in the 1D hydrophilic channel used to engender proton conductivity in MOFs. Its water adsorption isotherm at room temperature and pressure shows that the water content in it was 31 cm3 g-1 at the maximum allowable humidity, corresponding to 3.7 water molecules per unit formula. It exhibits good proton conductivities (10-4-10-3 S cm-1) at 100 °C in the relative humidity range 35-98%. The corresponding activation energy (Ea) of conductivity was estimated to be 1.01 eV.

  3. 3D mask modeling with oblique incidence and mask corner rounding effects for the 32nm node

    NASA Astrophysics Data System (ADS)

    Saied, Mazen; Foussadier, Franck; Belledent, Jérôme; Trouiller, Yorick; Schanen, Isabelle; Yesilada, Emek; Gardin, Christian; Urbani, Jean Christophe; Sundermann, Frank; Robert, Frédéric; Couderc, Christophe; Vautrin, Florent; LeCam, Laurent; Kerrien, Gurwan; Planchot, Jonathan; Martinelli, Catherine; Wilkinson, Bill; Rody, Yves; Borjon, Amandine; Morgana, Nicolo; Di-Maria, Jean-Luc; Farys, Vincent

    2007-10-01

    The perpetual shrinking in critical dimensions in semiconductor devices is driving the need for increased resolution in optical lithography. Increasing NA to gain resolution also increases Optical Proximity Correction (OPC) model complexity. Some optical effects which have been completely neglected in OPC modeling become important. Over the past few years, off-axis illumination has been widely used to improve the imaging process. OPC models which utilize such illumination still use the thin film mask approximation (Kirchhoff approach), during optical model generation, which utilizes a normal incidence. However, simulating a three dimensional mask near-field using an off-axis illumination requires OPC models to introduce oblique incidence. In addition, the use of higher NA systems introduces high obliquity field components that can no longer be assimilated as normal incident waves. The introduction of oblique incidence requires other effects, such as corner rounding of mask features, to be considered, that are seldom taken into account in OPC modeling. In this paper, the effects of oblique incidence and corner rounding of mask features on resist contours of 2D structures (i.e. line-ends and corners) are studied. Rigorous electromagnetic simulations are performed to investigate the scattering properties of various lithographic 32nm node mask structures. Simulations are conducted using a three dimensional phase shift mask topology and an off-axis illumination at high NA. Aerial images are calculated and compared with those obtained from a classical normal incidence illumination. The benefits of using an oblique incidence to improve hot-spot prediction will be discussed.

  4. 3D carotid plaque MR Imaging

    PubMed Central

    Parker, Dennis L.

    2015-01-01

    SYNOPSIS There has been significant progress made in 3D carotid plaque magnetic resonance imaging techniques in recent years. 3D plaque imaging clearly represents the future in clinical use. With effective flow suppression techniques, choices of different contrast weighting acquisitions, and time-efficient imaging approaches, 3D plaque imaging offers flexible imaging plane and view angle analysis, large coverage, multi-vascular beds capability, and even can be used in fast screening. PMID:26610656

  5. Comparing swimsuits in 3D.

    PubMed

    van Geer, Erik; Molenbroek, Johan; Schreven, Sander; deVoogd-Claessen, Lenneke; Toussaint, Huib

    2012-01-01

    In competitive swimming, suits have become more important. These suits influence friction, pressure and wave drag. Friction drag is related to the surface properties whereas both pressure and wave drag are greatly influenced by body shape. To find a relationship between the body shape and the drag, the anthropometry of several world class female swimmers wearing different suits was accurately defined using a 3D scanner and traditional measuring methods. The 3D scans delivered more detailed information about the body shape. On the same day the swimmers did performance tests in the water with the tested suits. Afterwards the result of the performance tests and the differences found in body shape was analyzed to determine the deformation caused by a swimsuit and its effect on the swimming performance. Although the amount of data is limited because of the few test subjects, there is an indication that the deformation of the body influences the swimming performance.

  6. A Randomized Controlled Trial to Test the Effectiveness of an Immersive 3D Video Game for Anxiety Prevention among Adolescents

    PubMed Central

    Scholten, Hanneke; Malmberg, Monique; Lobel, Adam; Engels, Rutger C. M. E.; Granic, Isabela

    2016-01-01

    Adolescent anxiety is debilitating, the most frequently diagnosed adolescent mental health problem, and leads to substantial long-term problems. A randomized controlled trial (n = 138) was conducted to test the effectiveness of a biofeedback video game (Dojo) for adolescents with elevated levels of anxiety. Adolescents (11–15 years old) were randomly assigned to play Dojo or a control game (Rayman 2: The Great Escape). Initial screening for anxiety was done on 1,347 adolescents in five high schools; only adolescents who scored above the “at-risk” cut-off on the Spence Children Anxiety Survey were eligible. Adolescents’ anxiety levels were assessed at pre-test, post-test, and at three month follow-up to examine the extent to which playing Dojo decreased adolescents’ anxiety. The present study revealed equal improvements in anxiety symptoms in both conditions at follow-up and no differences between Dojo and the closely matched control game condition. Latent growth curve models did reveal a steeper decrease of personalized anxiety symptoms (not of total anxiety symptoms) in the Dojo condition compared to the control condition. Moderation analyses did not show any differences in outcomes between boys and girls nor did age differentiate outcomes. The present results are of importance for prevention science, as this was the first full-scale randomized controlled trial testing indicated prevention effects of a video game aimed at reducing anxiety. Future research should carefully consider the choice of control condition and outcome measurements, address the potentially high impact of participants’ expectations, and take critical design issues into consideration, such as individual- versus group-based intervention and contamination issues. PMID:26816292

  7. A Randomized Controlled Trial to Test the Effectiveness of an Immersive 3D Video Game for Anxiety Prevention among Adolescents.

    PubMed

    Scholten, Hanneke; Malmberg, Monique; Lobel, Adam; Engels, Rutger C M E; Granic, Isabela

    2016-01-01

    Adolescent anxiety is debilitating, the most frequently diagnosed adolescent mental health problem, and leads to substantial long-term problems. A randomized controlled trial (n = 138) was conducted to test the effectiveness of a biofeedback video game (Dojo) for adolescents with elevated levels of anxiety. Adolescents (11-15 years old) were randomly assigned to play Dojo or a control game (Rayman 2: The Great Escape). Initial screening for anxiety was done on 1,347 adolescents in five high schools; only adolescents who scored above the "at-risk" cut-off on the Spence Children Anxiety Survey were eligible. Adolescents' anxiety levels were assessed at pre-test, post-test, and at three month follow-up to examine the extent to which playing Dojo decreased adolescents' anxiety. The present study revealed equal improvements in anxiety symptoms in both conditions at follow-up and no differences between Dojo and the closely matched control game condition. Latent growth curve models did reveal a steeper decrease of personalized anxiety symptoms (not of total anxiety symptoms) in the Dojo condition compared to the control condition. Moderation analyses did not show any differences in outcomes between boys and girls nor did age differentiate outcomes. The present results are of importance for prevention science, as this was the first full-scale randomized controlled trial testing indicated prevention effects of a video game aimed at reducing anxiety. Future research should carefully consider the choice of control condition and outcome measurements, address the potentially high impact of participants' expectations, and take critical design issues into consideration, such as individual- versus group-based intervention and contamination issues.

  8. Automated Quantification of DNA Demethylation Effects in Cells via 3D Mapping of Nuclear Signatures and Population Homogeneity Assessment1

    PubMed Central

    Gertych, Arkadiusz; Wawrowsky, Kolja A.; Lindsley, Erik; Vishnevsky, Eugene; Farkas, Daniel L.; Tajbakhsh, Jian

    2009-01-01

    Background Today’s advanced microscopic imaging applies to the preclinical stages of drug discovery that employ high-throughput and high-content three-dimensional (3D) analysis of cells to more efficiently screen candidate compounds. Drug efficacy can be assessed by measuring response homogeneity to treatment within a cell population. In this study topologically quantified nuclear patterns of methylated cytosine and global nuclear DNA are utilized as signatures of cellular response to the treatment of cultured cells with the demethylating anti-cancer agents: 5-azacytidine (5-AZA) and octreotide (OCT). Methods Mouse pituitary folliculostellate TtT-GF cells treated with 5-AZA and OCT for 48 hours, and untreated populations, were studied by immunofluorescence with a specific antibody against 5-methylcytosine (MeC), and 4,6-diamidino-2-phenylindole (DAPI) for delineation of methylated sites and global DNA in nuclei (n=163). Cell images were processed utilizing an automated 3D analysis software that we developed by combining seeded watershed segmentation to extract nuclear shells with measurements of Kullback-Leibler’s (K-L) divergence to analyze cell population homogeneity in the relative nuclear distribution patterns of MeC versus DAPI stained sites. Each cell was assigned to one of the four classes: similar, likely similar, unlikely similar and dissimilar. Results Evaluation of the different cell groups revealed a significantly higher number of cells with similar or likely similar MeC/DAPI patterns among untreated cells (~100%), 5-AZA-treated cells (90%), and a lower degree of same type of cells (64%) in the OCT-treated population. The latter group contained (28%) of unlikely similar or dissimilar (7%) cells. Conclusion Our approach was successful in the assessment of cellular behavior relevant to the biological impact of the applied drugs, i.e. the reorganization of MeC/DAPI distribution by demethylation. In a comparison with other metrics, K-L divergence has

  9. 3D field harmonics

    SciTech Connect

    Caspi, S.; Helm, M.; Laslett, L.J.

    1991-03-30

    We have developed an harmonic representation for the three dimensional field components within the windings of accelerator magnets. The form by which the field is presented is suitable for interfacing with other codes that make use of the 3D field components (particle tracking and stability). The field components can be calculated with high precision and reduced cup time at any location (r,{theta},z) inside the magnet bore. The same conductor geometry which is used to simulate line currents is also used in CAD with modifications more readily available. It is our hope that the format used here for magnetic fields can be used not only as a means of delivering fields but also as a way by which beam dynamics can suggest correction to the conductor geometry. 5 refs., 70 figs.

  10. Effective incorporating spatial information in a mutual information based 3D-2D registration of a CT volume to X-ray images.

    PubMed

    Zheng, Guoyan

    2010-10-01

    This paper addresses the problem of estimating the 3D rigid poses of a CT volume of an object from its 2D X-ray projection(s). We use maximization of mutual information, an accurate similarity measure for multi-modal and mono-modal image registration tasks. However, it is known that the standard mutual information measures only take intensity values into account without considering spatial information and their robustness is questionable. In this paper, instead of directly maximizing mutual information, we propose to use a variational approximation derived from the Kullback-Leibler bound. Spatial information is then incorporated into this variational approximation using a Markov random field model. The newly derived similarity measure has a least-squares form and can be effectively minimized by a multi-resolution Levenberg-Marquardt optimizer. Experiments were conducted on datasets from two applications: (a) intra-operative patient pose estimation from a limited number (e.g. 2) of calibrated fluoroscopic images, and (b) post-operative cup orientation estimation from a single standard X-ray radiograph with/without gonadal shielding. The experiment on intra-operative patient pose estimation showed a mean target registration accuracy of 0.8mm and a capture range of 11.5mm, while the experiment on estimating the post-operative cup orientation from a single X-ray radiograph showed a mean accuracy below 2 degrees for both anteversion and inclination. More importantly, results from both experiments demonstrated that the newly derived similarity measures were robust to occlusions in the X-ray image(s).

  11. Presentation of a High Resolution Time Lapse 3D Groundwater Model of Metsähovi for Calculating the Gravity Effect of Groundwater in Local Scale

    NASA Astrophysics Data System (ADS)

    Hokkanen, T. M.; Hartikainen, A.; Raja-Halli, A.; Virtanen, H.; Makinen, J.

    2015-12-01

    INTRODUCTION The aim of this study is to construct a fine resolution time lapse groundwater (GW) model of Metsähovi (MH). GW, geological, and soil moisture (SM) data were collected for several years to achieve the goal. The knowledge of the behavior of the GW at local scale is essential for superconductive gravimeter (SG) investigations performing in MH. DESCRIPTION OF THE DATA Almost 50 sensors have been recorded SM data some 6 years with 1 to 5 minutes sampling frequency. The GW table has been monitored, both in bedrock and in soil, in many stages with all together 15 piezometers. Two geological sampling campaigns were conducted to get the knowledge of hydrological properties of soil in the study area of 200×200 m2 around SG station in MH. PRINCIPLE OF TIME LAPSE 3D HYDROGEOLOGICAL MODEL The model of study site consists of the surfaces of ground and bedrock gridded with 2×2 m2 resolution. The height of GW table was interpolated to 2×2×0.1 m3 grid between GW and SM monitoring points. Close to the outline of the study site and areas lacking of sensors GW table was defined by extrapolation and considering the geological information of the area. The bedrock porosity is 2% and soil porosity determined by geological information and SM recordings is from 5 to 35%. Only fully saturated media is considered in the time lapse model excluding unsaturated one. BENEFICIERS With a new model the fluctuation of GW table can be followed with ranging time lapses from 1 minute to 1 month. The gravity effect caused by the variation of GW table can be calculated more accurate than before in MH. Moreover, the new model can be validated and refined by measured gravity, i.e. hydrological model can be improved by SG recordings (Figure 1).

  12. Effects of the 3D-clinorotation on endogenous substances of broccoli sprout (Brassica oleracea var. italica) and its food safety

    NASA Astrophysics Data System (ADS)

    Hiraishi, K.; Tomita-Yokotani, K.; Wakabayashi, K.; Hashimoto, H.; Miyagawa, T.; Yamashita, M.

    Habitation in outer space is one of our challenges in this century We are studying on space agriculture to provide foods for space living people However careful assessment should be made on the effects of exotic environment on the endogenous production of biologically active substances and food safety of plants cultivated in space Broccoli sprout Brassica oleracea var italica is known to produce sulforaphane 4-methylsulfinybutyl isothiocyanate which is effective to function as an antioxidant and enhance immunity Because of such substance it is recognized to be good food materials Broccoli sprouts were then cultivated for 3 days under the 3D-clinorotation The amount of sulforaphane produced by this treatment showed no significant difference compared to the ground control Secondly we examined population of microorganisms adhered on the surface of sprout cultivated under the 3D-clinorotation Number of the microorganisms colony formed was statistically higher than the control Mold species was identified to penicillium sp based on the microscopic observation Poor construction of plant cell wall elements cellulose lignin etc is well known effects of microgravity Defense function of the broccoli plant cells might be weakened against microorganism We also speculate other possible causes for the high rate of contamination such as photosynthetic activity of the plant or microclimate air flow heat transport and humidity around the seedling affected by pseudo-microgravity or the 3D-clinorotation Those factors may relate to the difference in proliferation

  13. The Synergistic Effects of Matrix Stiffness and Composition on the Response of Chondroprogenitor Cells in a 3D Precondensation Microenvironment.

    PubMed

    Carrion, Bita; Souzanchi, Mohammad F; Wang, Victor T; Tiruchinapally, Gopinath; Shikanov, Ariella; Putnam, Andrew J; Coleman, Rhima M

    2016-05-01

    Improve functional quality of cartilage tissue engineered from stem cells requires a better understanding of the functional evolution of native cartilage tissue. Therefore, a biosynthetic hydrogel was developed containing RGD, hyaluronic acid and/or type-I collagen conjugated to poly(ethylene glycol) acrylate to recapitulate the precondensation microenvironment of the developing limb. Conjugation of any combination of the three ligands did not alter the shear moduli or diffusion properties of the PEG hydrogels; thus, the influence of ligand composition on chondrogenesis could be investigated in the context of varying matrix stiffness. Gene expression of ligand receptors (CD44 and the b1-integrin) as well as markers of condensation (cell clustering and N-cadherin gene expression) and chondrogenesis (Col2a1 gene expression and sGAG production) by chondroprogenitor cells in this system were modulated by both matrix stiffness and ligand composition, with the highest gene expression occurring in softer hydrogels containing all three ligands. Cell proliferation in these 3D matrices for 7 d prior to chondrogenic induction increased the rate of sGAG production in a stiffness-dependent manner. This biosynthetic hydrogel supports the features of early limb-bud condensation and chondrogenesis and is a novel platform in which the influence of the matrix physicochemical properties on these processes can be elucidated.

  14. The effect of interface microstructure on interfacial shear strength for osteochondral scaffolds based on biomimetic design and 3D printing.

    PubMed

    Zhang, Weijie; Lian, Qin; Li, Dichen; Wang, Kunzheng; Hao, Dingjun; Bian, Weiguo; Jin, Zhongmin

    2015-01-01

    Interface integration between chondral phase and osseous phase is crucial in engineered osteochondral scaffolds. However, the integration was poorly understood and commonly failed to meet the need of osteochondral scaffolds. In this paper, a biphasic polyethylene glycol (PEG)/β-tricalcium phosphate (β-TCP) scaffold with enhanced interfacial integration was developed. The chondral phase was a PEG hydrogel. The osseous phase was a β-TCP ceramic scaffold. The PEG hydrogel was directly cured on the ceramic interface layer by layer to fabricate osteochondral scaffolds by 3D printing technology. Meanwhile, a series of interface structure were designed with different interface pore area percentages (0/10/20/30/40/50/60%), and interfacial shear test was applied for interface structure optimization (n=6 samples/group). The interfacial shear strength of 30% pore area group was nearly three folds improved compared with that of 0% pore area percentage group, and more than fifty folds improved compared with that of traditional integration (5.91±0.59 kPa). In conclusion, the biomimetic PEG/β-TCP scaffolds with interface structure enhanced integration show promising potential application for osteochondral tissue engineering.

  15. Experimental and numerical investigation into micro-flow cytometer with 3-D hydrodynamic focusing effect and micro-weir structure.

    PubMed

    Hou, Hui-Hsiung; Tsai, Chien-Hsiung; Fu, Lung-Ming; Yang, Ruey-Jen

    2009-07-01

    This study presents a novel 3-D hydrodynamic focusing technique for micro-flow cytometers. In the proposed approach, the sample stream is compressed initially in the horizontal direction by a set of sheath flows such that it is constrained to the central region of the microchannel and is then focused in the vertical direction by a second pair of sheath flows. Thereafter, the focused sample stream passes over a micro-weir structure positioned directly beneath an optical detection system to capture polystyrene beads fluorescent signal. The microchannel configuration and operational parameters are optimized by performing a series of numerical simulations. An experimental investigation is then performed using a micro-flow cytometer fabricated using conventional micro-electro-mechanical systems techniques and an isotropic wet etching method. The results indicate that the two sets of sheath flows successfully constrain the sample stream within a narrow, well-defined region of the microchannel. Furthermore, the micro-weir structure prompts the separation of a mixed sample of 5 and 10 microm polystyrene beads in the vertical direction and ensures that the beads flow through the detection region of the microchannel in a sequential fashion and can therefore be reliably detected and counted.

  16. Inverse current-source density method in 3D: reconstruction fidelity, boundary effects, and influence of distant sources.

    PubMed

    Łeski, Szymon; Wójcik, Daniel K; Tereszczuk, Joanna; Swiejkowski, Daniel A; Kublik, Ewa; Wróbel, Andrzej

    2007-01-01

    Estimation of the continuous current-source density in bulk tissue from a finite set of electrode measurements is a daunting task. Here we present a methodology which allows such a reconstruction by generalizing the one-dimensional inverse CSD method. The idea is to assume a particular plausible form of CSD within a class described by a number of parameters which can be estimated from available data, for example a set of cubic splines in 3D spanned on a fixed grid of the same size as the set of measurements. To avoid specificity of particular choice of reconstruction grid we add random jitter to the points positions and show that it leads to a correct reconstruction. We propose different ways of improving the quality of reconstruction which take into account the sources located outside the recording region through appropriate boundary treatment. The efficiency of the traditional CSD and variants of inverse CSD methods is compared using several fidelity measures on different test data to investigate when one of the methods is superior to the others. The methods are illustrated with reconstructions of CSD from potentials evoked by stimulation of a bunch of whiskers recorded in a slab of the rat forebrain on a grid of 4x5x7 positions.

  17. 3-D seismic evidence of the effects of carbonate karst collapse on overlying clastic stratigraphy and reservoir compartmentalization

    SciTech Connect

    Hardage, B.A.; Carr, D.L.; Simmons, J.L. Jr.; Jons, R.A.; Lancaster, D.E.; Elphick, R.Y.; Pendleton, V.M.

    1996-09-01

    A multidisciplinary team, composed of stratigraphers, petrophysicists, reservoir engineers, and geophysicists, studied a portion of Boonsville gas field in the Fort Worth Basin of north-central Texas to determine how modern techniques can be combined to understand the mechanisms by which fluvio-deltaic depositional processes create reservoir compartmentalization in a low- to moderate-accommodation basin. An extensive database involving well logs, cores, production, and pressure data from more than 200 wells, 26 mi{sup 2} of 3-D seismic data, vertical seismic profiles, and checkshots was assembled to support this investigation. The authors found the most important geologic influence on stratigraphy and reservoir compartmentalization in this basin to be the existence of numerous karst collapse chimneys over the area covered. These near-vertical karst collapses originated in, or near, the deep Ordovician-age Ellenburger carbonate section and created vertical chimneys extending as high as 2,500 ft above their point of origin, causing significant disruptions in the overlying clastic strata.

  18. Effect of time-dependent 3-D electron density gradients on high angle of incidence HF radiowave propagation

    NASA Astrophysics Data System (ADS)

    Zawdie, K. A.; Drob, D. P.; Huba, J. D.; Coker, C.

    2016-07-01

    One of the challenges for the utilization of HF radiowaves in practical applications is to understand how the signals propagate in time- and range-dependent multipath environments. For typical quiescent ionospheric conditions it is often reasonably straightforward to interpret received HF signals. For disturbed ionospheric conditions, however, such as in the presence of large tilts, irregularities, and medium-scale traveling ionospheric disturbances (MSTIDs), data interpretation and utilization often becomes challenging. This paper presents a theoretical HF propagation modeling study that exploits the capabilities of a first principles, mesoscale resolution ionosphere code, SAMI3 (Sami3 is Another Model of the Ionosphere) and a new implementation of the 3-D ray trace equations, MoJo-15 (Modernized Jones Code) in order to examine the relationship between various HF propagation observables and MSTID characteristics. This paper demonstrates the implications of MSTIDS on high angle of incidence HF propagation during typical low-latitude, postsunset ionospheric conditions and examines the spatiotemporal evolution of multiple propagation paths that may connect a given source and receiver.

  19. Evaluation of the combined effects of target size, respiratory motion and background activity on 3D and 4D PET/CT images

    NASA Astrophysics Data System (ADS)

    Park, Sang-June; Ionascu, Dan; Killoran, Joseph; Mamede, Marcelo; Gerbaudo, Victor H.; Chin, Lee; Berbeco, Ross

    2008-07-01

    Gated (4D) PET/CT has the potential to greatly improve the accuracy of radiotherapy at treatment sites where internal organ motion is significant. However, the best methodology for applying 4D-PET/CT to target definition is not currently well established. With the goal of better understanding how to best apply 4D information to radiotherapy, initial studies were performed to investigate the effect of target size, respiratory motion and target-to-background activity concentration ratio (TBR) on 3D (ungated) and 4D PET images. Using a PET/CT scanner with 4D or gating capability, a full 3D-PET scan corrected with a 3D attenuation map from 3D-CT scan and a respiratory gated (4D) PET scan corrected with corresponding attenuation maps from 4D-CT were performed by imaging spherical targets (0.5-26.5 mL) filled with 18F-FDG in a dynamic thorax phantom and NEMA IEC body phantom at different TBRs (infinite, 8 and 4). To simulate respiratory motion, the phantoms were driven sinusoidally in the superior-inferior direction with amplitudes of 0, 1 and 2 cm and a period of 4.5 s. Recovery coefficients were determined on PET images. In addition, gating methods using different numbers of gating bins (1-20 bins) were evaluated with image noise and temporal resolution. For evaluation, volume recovery coefficient, signal-to-noise ratio and contrast-to-noise ratio were calculated as a function of the number of gating bins. Moreover, the optimum thresholds which give accurate moving target volumes were obtained for 3D and 4D images. The partial volume effect and signal loss in the 3D-PET images due to the limited PET resolution and the respiratory motion, respectively were measured. The results show that signal loss depends on both the amplitude and pattern of respiratory motion. However, the 4D-PET successfully recovers most of the loss induced by the respiratory motion. The 5-bin gating method gives the best temporal resolution with acceptable image noise. The results based on the 4D

  20. Bioengineered 3D brain tumor model to elucidate the effects of matrix stiffness on glioblastoma cell behavior using PEG-based hydrogels.

    PubMed

    Wang, Christine; Tong, Xinming; Yang, Fan

    2014-07-07

    Glioblastoma (GBM) is the most common and aggressive form of primary brain tumor with a median survival of 12-15 months, and the mechanisms underlying GBM tumor progression remain largely elusive. Given the importance of tumor niche signaling in driving GBM progression, there is a strong need to develop in vitro models to facilitate analysis of brain tumor cell-niche interactions in a physiologically relevant and controllable manner. Here we report the development of a bioengineered 3D brain tumor model to help elucidate the effects of matrix stiffness on GBM cell fate using poly(ethylene-glycol) (PEG)-based hydrogels with brain-mimicking biochemical and mechanical properties. We have chosen PEG given its bioinert nature and tunable physical property, and the resulting hydrogels allow tunable matrix stiffness without changing the biochemical contents. To facilitate cell proliferation and migration, CRGDS and a MMP-cleavable peptide were chemically incorporated. Hyaluronic acid (HA) was also incorporated to mimic the concentration in the brain extracellular matrix. Using U87 cells as a model GBM cell line, we demonstrate that such biomimetic hydrogels support U87 cell growth, spreading, and migration in 3D over the course of 3 weeks in culture. Gene expression analyses showed U87 cells actively deposited extracellular matrix and continued to upregulate matrix remodeling genes. To examine the effects of matrix stiffness on GBM cell fate in 3D, we encapsulated U87 cells in soft (1 kPa) or stiff (26 kPa) hydrogels, which respectively mimics the matrix stiffness of normal brain or GBM tumor tissues. Our results suggest that changes in matrix stiffness induce differential GBM cell proliferation, morphology, and migration modes in 3D. Increasing matrix stiffness led to delayed U87 cell proliferation inside hydrogels, but cells formed denser spheroids with extended cell protrusions. Cells cultured in stiff hydrogels also showed upregulation of HA synthase 1 and matrix

  1. Magmatic Systems in 3-D

    NASA Astrophysics Data System (ADS)

    Kent, G. M.; Harding, A. J.; Babcock, J. M.; Orcutt, J. A.; Bazin, S.; Singh, S.; Detrick, R. S.; Canales, J. P.; Carbotte, S. M.; Diebold, J.

    2002-12-01

    Multichannel seismic (MCS) images of crustal magma chambers are ideal targets for advanced visualization techniques. In the mid-ocean ridge environment, reflections originating at the melt-lens are well separated from other reflection boundaries, such as the seafloor, layer 2A and Moho, which enables the effective use of transparency filters. 3-D visualization of seismic reflectivity falls into two broad categories: volume and surface rendering. Volumetric-based visualization is an extremely powerful approach for the rapid exploration of very dense 3-D datasets. These 3-D datasets are divided into volume elements or voxels, which are individually color coded depending on the assigned datum value; the user can define an opacity filter to reject plotting certain voxels. This transparency allows the user to peer into the data volume, enabling an easy identification of patterns or relationships that might have geologic merit. Multiple image volumes can be co-registered to look at correlations between two different data types (e.g., amplitude variation with offsets studies), in a manner analogous to draping attributes onto a surface. In contrast, surface visualization of seismic reflectivity usually involves producing "fence" diagrams of 2-D seismic profiles that are complemented with seafloor topography, along with point class data, draped lines and vectors (e.g. fault scarps, earthquake locations and plate-motions). The overlying seafloor can be made partially transparent or see-through, enabling 3-D correlations between seafloor structure and seismic reflectivity. Exploration of 3-D datasets requires additional thought when constructing and manipulating these complex objects. As numbers of visual objects grow in a particular scene, there is a tendency to mask overlapping objects; this clutter can be managed through the effective use of total or partial transparency (i.e., alpha-channel). In this way, the co-variation between different datasets can be investigated

  2. Chrysotile effects on human lung cell carcinoma in culture: 3-D reconstruction and DNA quantification by image analysis

    PubMed Central

    Cortez, Beatriz A; Machado-Santelli, Glaucia M

    2008-01-01

    Background Chrysotile is considered less harmful to human health than other types of asbestos fibers. Its clearance from the lung is faster and, in comparison to amphibole forms of asbestos, chrysotile asbestos fail to accumulate in the lung tissue due to a mechanism involving fibers fragmentation in short pieces. Short exposure to chrysotile has not been associated with any histopathological alteration of lung tissue. Methods The present work focuses on the association of small chrysotile fibers with interphasic and mitotic human lung cancer cells in culture, using for analyses confocal laser scanning microscopy and 3D reconstructions. The main goal was to perform the analysis of abnormalities in mitosis of fibers-containing cells as well as to quantify nuclear DNA content of treated cells during their recovery in fiber-free culture medium. Results HK2 cells treated with chrysotile for 48 h and recovered in additional periods of 24, 48 and 72 h in normal medium showed increased frequency of multinucleated and apoptotic cells. DNA ploidy of the cells submitted to the same chrysotile treatment schedules showed enhanced aneuploidy values. The results were consistent with the high frequency of multipolar spindles observed and with the presence of fibers in the intercellular bridge during cytokinesis. Conclusion The present data show that 48 h chrysotile exposure can cause centrosome amplification, apoptosis and aneuploid cell formation even when long periods of recovery were provided. Internalized fibers seem to interact with the chromatin during mitosis, and they could also interfere in cytokinesis, leading to cytokinesis failure which forms aneuploid or multinucleated cells with centrosome amplification. PMID:18588678

  3. Synergistic Effects of 3D ECM and Chemogradients on Neurite Outgrowth and Guidance: A Simple Modeling and Microfluidic Framework

    PubMed Central

    Srinivasan, Parthasarathy; Zervantonakis, Ioannis K.; Kothapalli, Chandrasekhar R.

    2014-01-01

    During nervous system development, numerous cues within the extracellular matrix microenvironment (ECM) guide the growing neurites along specific pathways to reach their intended targets. Neurite motility is controlled by extracellular signal sensing through the growth cone at the neurite tip, including chemoattractive and repulsive cues. However, it is difficult to regenerate and restore neurite tracts, lost or degraded due to an injury or disease, in the adult central nervous system. Thus, it is important to evaluate the dynamic interplay between ECM and the concentration gradients of these cues, which would elicit robust neuritogenesis. Such information is critical in understanding the processes involved in developmental biology, and in developing high-fidelity neurite regenerative strategies post-injury, and in drug discovery and targeted therapeutics for neurodegenerative conditions. Here, we quantitatively investigated this relationship using a combination of mathematical modeling and in vitro experiments, and determined the synergistic role of guidance cues and ECM on neurite outgrowth and turning. Using a biomimetic microfluidic system, we have shown that cortical neurite outgrowth and turning under chemogradients (IGF-1 or BDNF) within 3D scaffolds is highly regulated by the source concentration of the guidance cue and the physical characteristics of the scaffold. A mechanistic-driven partial differential equation model of neurite outgrowth has been proposed, which could also be used prospectively as a predictive tool. The parameters for the chemotaxis term in the model are determined from the experimental data using our microfluidic assay. Resulting model simulations demonstrate how neurite outgrowth was critically influenced by the experimental variables, which was further supported by experimental data on cell-surface-receptor expressions. The model results are in excellent agreement with the experimental findings. This integrated approach represents a

  4. Investigating the neuroglial differentiation effect of neuroblastoma conditioned medium in human endometrial stem cells cultured on 3D nanofibrous scaffold.

    PubMed

    Ebrahimi-Barough, Somayeh; Hoveizi, Elham; Norouzi Javidan, Abbas; Ai, Jafar

    2015-08-01

    Neural tissue engineering is an important area of research in the field of tissue-engineering especially for neurodegenerative disease such as spinal cord injury. The differentiation capacity of human endometrial stem cells (hEnSCs) into neuronal cells has yet to be elucidated. Here, the major aim of the present study was to investigate the differentiation ability of hEnSCs cultured on polylactic acid/chitosan (PLA/CS) nanofibrous scaffold into neuroglial cells in response to conditioned medium of BE(2)-C human neuroblastoma cells and growth factors. Here we investigated the use PLA/CS scaffold as a three dimensional (3D) system that increased neuro-glial cells differentiation. Human EnSCs after three passages were differentiated in neuro-glial like cells under neuroblastoma conditioned medium with FGF2/PDGF-AA on PLA/CS scaffold. By day 18, differentiated cells were analyzed for expression of neuroglial markers by qRT-PCR and immunofluorescence. The results revealed that hEnSCs attach, grow and differentiation on the nanofibrous PLA/CS scaffold. Additionally, our study showed the expression of neural and glial lineage markers such as Nestin, NF-L, MAP2, PDGFRa, CNP, Olig2, MBP, and GFAP in the level of mRNA and MAP2, Tuj-1, and NF-L in the protein level after 18 days. Our results demonstrate that hEnSCs cultured on PLA/CS nanofibrous scaffold have the potential to differentiate in neuronal and glial cells in presence of neuroblastoma conditioned medium on PLA/CS scaffold. The result of this study may have impact in tissue engineering and cells-base therapy of neurodegenerative diseases and have a great potential for wide application.

  5. Effective Thermal Conductivity of Corrugated Insulating Materials

    NASA Astrophysics Data System (ADS)

    Yamada, Etsuro; Kato, Masayasu; Tomikawa, Takayuki; Takahashi, Kaneko

    The effective thermal conductivity of corrugated insulating materials which are made by polypropylene or polycarbonate have been measured by employing steady state comparison method for several specimen having various thickness and specific weight. The thermal conductivity of them evaluated are also by using the thermal resistance models, and are compared with above measured values and raw materials' conductivity. The main results obtained in this paper are as follows: (1) In regard to the specimen in this paper, the effective thermal conductivity increases with increasing temperature, but the increasing rate of them is small. (2) There are considerable differences between the measured values and the predicted ones that are estimated by using the thermal resistance model in which heat flow by conduction only. This differences increase with increasing specimens' thickness. This difference become extinct by considering the coexistence heat flow of conduction and radiation in the air phase of specimen. (3) The thermal resistance of specimen increases linearly with increasing specimens' thickness.

  6. Shape corrections for 3D EIT

    NASA Astrophysics Data System (ADS)

    Paridis, Kyriakos; Lionheart, William R. B.

    2010-04-01

    Movement of the boundary in biomedical Electrical Impedance Tomography (EIT) has been always a source of error in image reconstruction. In the case of pulmonary EIT, where the patient's chest shape changes during respiration, this is inevitable, so it is essential to be able to correct for shape changes and consequently avoid artifacts. Assuming that the conductivity is isotropic, an assumption that is reasonable for lung tissue but admittedly violated for muscle, the boundary shape up to a Möbius transformation (conformal mapping) as well as the conductivity can theoretically be determined by 3D EIT data. While in two dimensions the space of conformal mappings are infinite dimensional, in the three dimensional case the Möbius transformations are given by a finite number of parameters. In this paper, we concentrate on the three dimensional case and take a linear approximation. We will give results of numerical studies analogous to the two dimensional work of Boyle et al on the effect of electrode movement and shape error in 3D EIT.

  7. SU-E-J-80: Interplay Effect Between VMAT Intensity Modulation and Tumor Motion in Hypofractioned Lung Treatment, Investigated with 3D Pressage Dosimeter

    SciTech Connect

    Touch, M; Wu, Q; Oldham, M

    2014-06-01

    Purpose: To demonstrate an embedded tissue equivalent presage dosimeter for measuring 3D doses in moving tumors and to study the interplay effect between the tumor motion and intensity modulation in hypofractioned Volumetric Modulated Arc Therapy(VMAT) lung treatment. Methods: Motion experiments were performed using cylindrical Presage dosimeters (5cm diameter by 7cm length) mounted inside the lung insert of a CIRS thorax phantom. Two different VMAT treatment plans were created and delivered in three different scenarios with the same prescribed dose of 18 Gy. Plan1, containing a 2 centimeter spherical CTV with an additional 2mm setup margin, was delivered on a stationary phantom. Plan2 used the same CTV except expanded by 1 cm in the Sup-Inf direction to generate ITV and PTV respectively. The dosimeters were irradiated in static and variable motion scenarios on a Truebeam system. After irradiation, high resolution 3D dosimetry was performed using the Duke Large Field-of-view Optical-CT Scanner, and compared to the calculated dose from Eclipse. Results: In the control case (no motion), good agreement was observed between the planned and delivered dose distributions as indicated by 100% 3D Gamma (3% of maximum planned dose and 3mm DTA) passing rates in the CTV. In motion cases gamma passing rates was 99% in CTV. DVH comparisons also showed good agreement between the planned and delivered dose in CTV for both control and motion cases. However, differences of 15% and 5% in dose to PTV were observed in the motion and control cases respectively. Conclusion: With very high dose nature of a hypofraction treatment, significant effect was observed only motion is introduced to the target. This can be resulted from the motion of the moving target and the modulation of the MLC. 3D optical dosimetry can be of great advantage in hypofraction treatment dose validation studies.

  8. NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration.

    PubMed

    Zhong, Jessie; Baquiran, Jaime B; Bonakdar, Navid; Lees, Justin; Ching, Yu Wooi; Pugacheva, Elena; Fabry, Ben; O'Neill, Geraldine M

    2012-01-01

    The speed of cell migration on 2-dimensional (2D) surfaces is determined by the rate of assembly and disassembly of clustered integrin receptors known as focal adhesions. Different modes of cell migration that have been described in 3D environments are distinguished by their dependence on integrin-mediated interactions with the extra-cellular matrix. In particular, the mesenchymal invasion mode is the most dependent on focal adhesion dynamics. The focal adhesion protein NEDD9 is a key signalling intermediary in mesenchymal cell migration, however whether NEDD9 plays a role in regulating focal adhesion dynamics has not previously been reported. As NEDD9 effects on 2D migration speed appear to depend on the cell type examined, in the present study we have used mouse embryo fibroblasts (MEFs) from mice in which the NEDD9 gene has been depleted (NEDD9 -/- MEFs). This allows comparison with effects of other focal adhesion proteins that have previously been demonstrated using MEFs. We show that focal adhesion disassembly rates are increased in the absence of NEDD9 expression and this is correlated with increased paxillin phosphorylation at focal adhesions. NEDD9-/- MEFs have increased rates of migration on 2D surfaces, but conversely, migration of these cells is significantly reduced in 3D collagen gels. Importantly we show that myosin light chain kinase is activated in 3D in the absence of NEDD9 and is conversely inhibited in 2D cultures. Measurement of adhesion strength reveals that NEDD9-/- MEFs have decreased adhesion to fibronectin, despite upregulated α5β1 fibronectin receptor expression. We find that β1 integrin activation is significantly suppressed in the NEDD9-/-, suggesting that in the absence of NEDD9 there is decreased integrin receptor activation. Collectively our data suggest that NEDD9 may promote 3D cell migration by slowing focal adhesion disassembly, promoting integrin receptor activation and increasing adhesion force to the ECM.

  9. How We 3D-Print Aerogel

    SciTech Connect

    2015-04-23

    A new type of graphene aerogel will make for better energy storage, sensors, nanoelectronics, catalysis and separations. Lawrence Livermore National Laboratory researchers have made graphene aerogel microlattices with an engineered architecture via a 3D printing technique known as direct ink writing. The research appears in the April 22 edition of the journal, Nature Communications. The 3D printed graphene aerogels have high surface area, excellent electrical conductivity, are lightweight, have mechanical stiffness and exhibit supercompressibility (up to 90 percent compressive strain). In addition, the 3D printed graphene aerogel microlattices show an order of magnitude improvement over bulk graphene materials and much better mass transport.

  10. Intraoral 3D scanner

    NASA Astrophysics Data System (ADS)

    Kühmstedt, Peter; Bräuer-Burchardt, Christian; Munkelt, Christoph; Heinze, Matthias; Palme, Martin; Schmidt, Ingo; Hintersehr, Josef; Notni, Gunther

    2007-09-01

    Here a new set-up of a 3D-scanning system for CAD/CAM in dental industry is proposed. The system is designed for direct scanning of the dental preparations within the mouth. The measuring process is based on phase correlation technique in combination with fast fringe projection in a stereo arrangement. The novelty in the approach is characterized by the following features: A phase correlation between the phase values of the images of two cameras is used for the co-ordinate calculation. This works contrary to the usage of only phase values (phasogrammetry) or classical triangulation (phase values and camera image co-ordinate values) for the determination of the co-ordinates. The main advantage of the method is that the absolute value of the phase at each point does not directly determine the coordinate. Thus errors in the determination of the co-ordinates are prevented. Furthermore, using the epipolar geometry of the stereo-like arrangement the phase unwrapping problem of fringe analysis can be solved. The endoscope like measurement system contains one projection and two camera channels for illumination and observation of the object, respectively. The new system has a measurement field of nearly 25mm × 15mm. The u