Science.gov

Sample records for 3rd year continuation

  1. Small scale laboratory studies of flow and transport phenomena in pores and fractures: Phase II. Progress report, 3rd year continuation proposal, and work plan

    SciTech Connect

    Wilson, J.L.

    1994-05-01

    Small scale laboratory experiments, equipped with an ability to actually observe behavior on the pore level using microscopy, provide an economical and easily understood scientific tool to help us validate concepts and assumptions about the transport of contaminants, and offers the propensity to discover heretofore unrecognized phenomena or behavior. The main technique employs etched glass micromodels, composed of two etched glass plates, sintered together, to form a two dimensional network of three dimensional pores. Flow and transport behavior is observed on a pore or pore network level, and recorder on film and video tape. This technique is coupled with related column studies. These techniques have been used to study multiphase flow, colloid transport and most recently bacteria transport. The project has recently moved to the Bacteria Transport Subprogram, and efforts have been redirected to support that Subprogram and its collaborative field experiment. We proposed to study bacteria transport factors of relevance to the field experiment, using micromodels and other laboratory techniques. Factors that may be addressed include bacteria characteristics (eg, hydrophobicity), pore size and shape, permeability heterogeneity, surface chemistry (eg, iron oxide coatings), surface chemistry heterogeneity, active versus resting cell bacteria, and mixed bacteria populations. In other work we will continue to examine the effects of fluid-fluid interfaces on bacteria transport, and develop a new assay for bacteria hydrophobicity. Finally we will collaborate on characterization of the field site, and the design, operation, and interpretation of the field experiment.

  2. Mathematics in Early Years Education. 3rd Edition

    ERIC Educational Resources Information Center

    Montague-Smith, Ann; Price, Alison

    2012-01-01

    This third edition of the best-selling "Mathematics in Nursery Education" provides an accessible introduction to the teaching of mathematics in the early years. Covering all areas of mathematics learning--number and counting, calculation, pattern, shape, measures and data handling--it summarises the research findings and underlying key concepts…

  3. Performance Plan: Progress Report, 3rd Quarter Fiscal Year 2000.

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC. Student Financial Assistance.

    The U.S. Department of Education Student Financial Assistance (SFA) outlines its three major objectives for fiscal year 2000 in its progress report. The objectives are: 1)customer satisfaction; 2) reduction in the overall cost of delivering student aid; and 3) employee satisfaction. Several new capabilities were added to the Direct Loan servicing…

  4. Radiographic findings on 3rd molars removed in 20-year-old men.

    PubMed

    Rajasuo, Ari; Peltola, Jaakko; Ventä, Irja; Murtomaa, Heikki

    2003-10-01

    In this study we assess radiographic findings characteristic of mandibular 3rd molars that had required either routine or surgical extraction. X-ray findings relating to acute pericoronitis were also examined. The material was collected by investigating patient records and rotational panoramic radiographs of 20-year-old Finnish male conscripts (n = 738) treated during military service because of 3rd-molar-related problems. The follicle around the crown of mandibular 3rd molars with acute pericoronitis was enlarged in 19% of cases and in 13% of chronic symptom-free pericoronitis cases (not statistically significant difference). Mandibular 3rd molars extracted surgically were more often mesially inclined than those extracted routinely (61% vs. 23%; P < 0.001), partially or totally intrabony impacted (92% vs. 66%; P < 0.001) and deep situated (on average 4.2 mm vs. 2.5 mm under the occlusal plane). Surgical extraction was also associated with the roots completely developed [92% vs. 84% of the teeth routinely extracted, odds ratio (OR) 2.6, 95% confidence interval (CI) 1.2-5.5] and with the absence of radiographic pericoronitis [around 27% vs. 39% of the teeth routinely extracted (OR 0.5, 95% CI 0.3-0.8)]. In 86% of cases the space between 2nd molar and ramus of the mandible was narrower than the 3rd molar extracted surgically, whereas this was 62% in routine extraction cases (P < 0.001). We conclude that there are some typical 3rd-molar findings in rotational panoramic radiographs that show a need for surgical extraction.

  5. Radiographic findings on 3rd molars removed in 20-year-old men.

    PubMed

    Rajasuo, Ari; Peltola, Jaakko; Ventä, Irja; Murtomaa, Heikki

    2003-10-01

    In this study we assess radiographic findings characteristic of mandibular 3rd molars that had required either routine or surgical extraction. X-ray findings relating to acute pericoronitis were also examined. The material was collected by investigating patient records and rotational panoramic radiographs of 20-year-old Finnish male conscripts (n = 738) treated during military service because of 3rd-molar-related problems. The follicle around the crown of mandibular 3rd molars with acute pericoronitis was enlarged in 19% of cases and in 13% of chronic symptom-free pericoronitis cases (not statistically significant difference). Mandibular 3rd molars extracted surgically were more often mesially inclined than those extracted routinely (61% vs. 23%; P < 0.001), partially or totally intrabony impacted (92% vs. 66%; P < 0.001) and deep situated (on average 4.2 mm vs. 2.5 mm under the occlusal plane). Surgical extraction was also associated with the roots completely developed [92% vs. 84% of the teeth routinely extracted, odds ratio (OR) 2.6, 95% confidence interval (CI) 1.2-5.5] and with the absence of radiographic pericoronitis [around 27% vs. 39% of the teeth routinely extracted (OR 0.5, 95% CI 0.3-0.8)]. In 86% of cases the space between 2nd molar and ramus of the mandible was narrower than the 3rd molar extracted surgically, whereas this was 62% in routine extraction cases (P < 0.001). We conclude that there are some typical 3rd-molar findings in rotational panoramic radiographs that show a need for surgical extraction. PMID:14763776

  6. Multibar sawless lint cleaner: fiber quality analysis after 3rd year of field testing

    Technology Transfer Automated Retrieval System (TEKTRAN)

    After two years of field testing a prototype spiked-tooth lint cleaner, the Multibar Sawless Lint Cleaner (MBSLC), a final year of field evaluation was conducted at commercial cotton gin in West Texas located approximately 30 miles Southwest of Lubbock, Texas.The cotton lint cleaner was tested in a ...

  7. The Loss of Student Idealism in the 3rd-Year Clinical Clerkships.

    ERIC Educational Resources Information Center

    Griffith, Charles H., III; Wilson, John F.

    2001-01-01

    Studied how student attitudes toward different types of patients and the medical profession change during clinical rotations. Responses of 88 third-year medical students show that students became less idealistic toward the elderly and people with chronic pain and less idealistic toward the profession. (SLD)

  8. Higher Education Financing in the Fifty States: Interstate Comparisons Fiscal Year 1981. 3rd Edition.

    ERIC Educational Resources Information Center

    McCoy, Marilyn; Halstead, D. Kent

    Information on state-level financing of higher education and on institutional revenues and expenditures is presented for fiscal year 1981. State rankings are provided on state and local government finances, support of colleges, and other trend data. Each state report consists of eight pages and is divided into eight topics: commentary on unique…

  9. Evaluation of a model of dissertation supervision for 3rd year B.Sc. undergraduate nursing students.

    PubMed

    Scholefield, Donna; Cox, Georgina

    2016-03-01

    All English universities now offer an all degree undergraduate nursing programme. Many currently use an individual supervision model to support final year dissertation students, but with increased numbers and limited resources new models of supervision are needed. This study evaluated a mixed (group and individual) model of dissertation supervision to determine its effectiveness for a large group of undergraduate nursing students. A sample of 3rd year students and their supervisors were selected from one large university. An evaluation survey was conducted using anonymous internet-based questionnaires and focus groups. The data was analysed using Survey Monkey, SPSS and thematic analysis. A 51% (n = 56/110) response rate (students) and 65% (n = 24/37) for supervisors was obtained. The majority of students and supervisors were satisfied with the new model. There was a mixed response to the group workshops and supervision groups. Three themes emerged from the qualitative data: engaging with the process, motivation to supervise and valuing the process. The supervision process is a struggle but both parties gained considerably from going through the process. In conclusion, a mixed model of supervision together with a range of other learning resources can be an effective approach in supporting students through the dissertation process. PMID:26700648

  10. Evaluation of a model of dissertation supervision for 3rd year B.Sc. undergraduate nursing students.

    PubMed

    Scholefield, Donna; Cox, Georgina

    2016-03-01

    All English universities now offer an all degree undergraduate nursing programme. Many currently use an individual supervision model to support final year dissertation students, but with increased numbers and limited resources new models of supervision are needed. This study evaluated a mixed (group and individual) model of dissertation supervision to determine its effectiveness for a large group of undergraduate nursing students. A sample of 3rd year students and their supervisors were selected from one large university. An evaluation survey was conducted using anonymous internet-based questionnaires and focus groups. The data was analysed using Survey Monkey, SPSS and thematic analysis. A 51% (n = 56/110) response rate (students) and 65% (n = 24/37) for supervisors was obtained. The majority of students and supervisors were satisfied with the new model. There was a mixed response to the group workshops and supervision groups. Three themes emerged from the qualitative data: engaging with the process, motivation to supervise and valuing the process. The supervision process is a struggle but both parties gained considerably from going through the process. In conclusion, a mixed model of supervision together with a range of other learning resources can be an effective approach in supporting students through the dissertation process.

  11. Medical school curriculum characteristics associated with intentions and frequency of tobacco dependence treatment among 3rd year U.S. medical students

    PubMed Central

    Hayes, Rashelle B.; Geller, Alan C.; Crawford, Sybil L.; Jolicoeur, Denise; Churchill, Linda C.; Okuyemi, Kola; David, Sean P.; Adams, Michael; Waugh, Jonathan; Allen, Sharon S.; Leone, Frank T.; Fauver, Randy; Leung, Katherine; Liu, Qin; Ockene, Judith K.

    2015-01-01

    Objective Physicians play a critical role in addressing tobacco dependence, yet report limited training. Tobacco dependence treatment curricula for medical students could improve performance in this area. This study identified student and medical school tobacco treatment curricula characteristics associated with intentions and use of the 5As for tobacco treatment among 3rd year U.S. medical students. Methods Third year medical students (N=1065, 49.3% male) from 10 U.S. medical schools completed a survey in 2009-2010 assessing student characteristics, including demographics, tobacco treatment knowledge, and self-efficacy. Tobacco curricula characteristics assessed included amount and type of classroom instruction, frequency of tobacco treatment observation, instruction, and perception of preceptors as role models. Results Greater tobacco treatment knowledge, self-efficacy, and curriculum-specific variables were associated with 5A intentions, while younger age, tobacco treatment self-efficacy, intentions, and each curriculum-specific variable was associated with greater 5A behaviors. When controlling for important student variables, greater frequency of receiving 5A instruction (OR = 1.07; 95%CI 1.01-1.12) and perception of preceptors as excellent role models in tobacco treatment (OR = 1.35; 95%CI 1.04-1.75) were significant curriculum predictors of 5A intentions. Greater 5A instruction (B = .06 (.03); p< .05) and observation of tobacco treatment (B= .35 (.02); p< .001) were significant curriculum predictors of greater 5A behaviors. Conclusions Greater exposure to tobacco treatment teaching during medical school is associated with both greater intentions to use and practice tobacco 5As. Clerkship preceptors, or those physicians who provide training to medical students, may be particularly influential when they personally model and instruct students in tobacco dependence treatment. PMID:25572623

  12. Not Aid, Cooperation. European Congress on Continuing Education and Training (3rd, Berlin, Federal Republic of Germany, March 14-15, 1991).

    ERIC Educational Resources Information Center

    CEDEFOP Flash, 1991

    1991-01-01

    A congress on continuing education and training attended by participants from more than 20 Eastern and Western European countries is summarized in this document. Topics discussed at the plenary sessions, panel discussions, and nine workshops included the following: cooperation between Eastern and Western Europe; the role of the social partners in…

  13. 3rd annual symposium of chemical and pharmaceutical structure analysis.

    PubMed

    Weng, Naidong; Zheng, Jenny; Lee, Mike

    2012-08-01

    The 3rd Annual Symposium on Chemical and Pharmaceutical Structure Analysis was once again held in Shanghai, where a rich history of 'East meets West' continued. This meeting is dedicated to bringing together scientists from pharmaceutical companies, academic institutes, CROs and instrument vendors to discuss current challenges and opportunities on the forefront of pharmaceutical research and development. The diversified symposia and roundtables are highly interactive events where scientists share their experiences and visions in a collegial setting. The symposium highlighted speakers and sessions that provided first-hand experiences as well as the latest guidance and industrial/regulatory thinking, which was reflected by the theme of this year's meeting 'From Bench to Decision Making - from Basics to Application.' In addition to the highly successful Young Scientist Excellence Award, new events were featured at this year's meeting, such as the Executive Roundtable and the inaugural Innovator Award.

  14. Lucky guess or knowledge: a cross-sectional study using the Bland and Altman analysis to compare confidence-based testing of pharmacological knowledge in 3rd and 5th year medical students.

    PubMed

    Kampmeyer, Daniela; Matthes, Jan; Herzig, Stefan

    2015-05-01

    Multiple-choice-questions are common in medical examinations, but guessing biases assessment results. Confidence-based-testing (CBT) integrates indicated confidence levels. It has been suggested that correctness of and confidence in an answer together indicate knowledge levels thus determining the quality of a resulting decision. We used a CBT approach to investigate whether decision quality improves during undergraduate medical education. 3rd- and 5th-year students attended formative multiple-choice exams on pharmacological issues. Students were asked to indicate their confidence in a given answer. Correctness of answers was scored binary (1-correct; 0-wrong) and confidence levels were transformed to an ordinal scale (guess: 0; rather unsure: 0.33; rather sure: 0.66; very sure: 1). 5th-year students gave more correct answers (73 ± 16 vs. 49 ± 13 %, p < 0.05) and were on average more confident regarding the correctness of their answers (0.61 ± 0.18 vs. 0.46 ± 0.13, p < 0.05). Correlation of these parameters was stronger for 5th-year students (r = 0.81 vs. r = 0.52), but agreement of confidence and correctness ('centration') was lower. By combining the Bland-and-Altman approach with categories of decision-quality we found that 5th-year students were more likely to be 'well-informed' (41 vs. 5 %), while more 3rd-students were 'uninformed' (24 vs. 76 %). Despite a good correlation of exam results and confidence in given answers increased knowledge might be accompanied by a more critical view at the own abilities. Combining the statistical Bland-and-Altman analysis with a theoretical approach to decision-quality, more advanced students are expected to apply correct beliefs, while their younger fellows are rather at risk to hesitate or to act amiss.

  15. The Ups and Downs of 3rd Grade

    ERIC Educational Resources Information Center

    Felton, Kelsey Augst; Akos, Patrick

    2011-01-01

    The transition from 2nd to 3rd grade has received little notice in education research--yet the authors' experience in elementary school counseling convinced them that most students undergo a seismic shift during this period. Third grade is not only the first year students will encounter standardized end-of-grade tests, but also a year in which…

  16. Perspectives for Continuing Education and Training: Cooperation between Western and Eastern Europe. European Congress on Continuing Education and Training (3rd, Berlin, Germany, March 14-15, 1991). Congress Papers.

    ERIC Educational Resources Information Center

    Wollschlager, Norbert, Ed.

    The proceedings of the congress include the following workshop summaries: "Continuing Education and Training (CET) and Society" (Sellin); "The Social Dialogue" (Smith); "The Role of the Social Partners in Vocational and Further Training in Denmark" (Jensen); "Problems of Vocational Training in the Period of Transition to the Market Economy"…

  17. 2nd & 3rd Generation Vehicle Subsystems

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This paper contains viewgraph presentation on the "2nd & 3rd Generation Vehicle Subsystems" project. The objective behind this project is to design, develop and test advanced avionics, power systems, power control and distribution components and subsystems for insertion into a highly reliable and low-cost system for a Reusable Launch Vehicles (RLV). The project is divided into two sections: 3rd Generation Vehicle Subsystems and 2nd Generation Vehicle Subsystems. The following topics are discussed under the first section, 3rd Generation Vehicle Subsystems: supporting the NASA RLV program; high-performance guidance & control adaptation for future RLVs; Evolvable Hardware (EHW) for 3rd generation avionics description; Scaleable, Fault-tolerant Intelligent Network or X(trans)ducers (SFINIX); advance electric actuation devices and subsystem technology; hybrid power sources and regeneration technology for electric actuators; and intelligent internal thermal control. Topics discussed in the 2nd Generation Vehicle Subsystems program include: design, development and test of a robust, low-maintenance avionics with no active cooling requirements and autonomous rendezvous and docking systems; design and development of a low maintenance, high reliability, intelligent power systems (fuel cells and battery); and design of a low cost, low maintenance high horsepower actuation systems (actuators).

  18. Structures IVHM for 3rd Generation RLVs

    NASA Technical Reports Server (NTRS)

    Rogowski, Robert S.

    2000-01-01

    The primary goal of a Structures Integrated Vehicle Health Management (IVHM) system for 3rd generation Reusable Launch Vehicles (RLV) is to provide near 100% structural sensing coverage and thus eliminate both routine, and especially unplanned, inspections which are costly and time consuming. To meet this goal, significant advances in sensing and measurement system technology, data systems architectures, and structures based analysis methodology will be required to enable the needed large numbers of sensors with little weight penalty. This program will leverage X-33, 2nd Gen RLV, Shuttle, and Aviation Safety SIVHM system development experience to address this goal.

  19. The outcomes of therapeutic decision in lower 3rd rectal cancer patients.

    PubMed

    Chen, Chien-Hsin; Wei, Po-Li; Hsieh, Mao-Chih; Lin, En-Kwang; Chiou, Jeng-Fong; Lu, Yen-Jung; Wu, Szu-Yuan

    2016-09-01

    To investigate the outcomes of the selective neoadjuvant concurrent chemoradiotherapy (CCRT) in lower 3rd rectal cancer patients in different groups (with or without neoadjuvant CCRT), especially in survival rate, local recurrence rate, and sphincter preservation rate.From January 1999 to December 2012, 69 consecutive patients who had histologically proven adenocarcinoma of lower 3rd rectum, defined preoperatively as lower tumor margin within 7 cm from the anal verge as measured by rigid sigmoidoscopy, received total mesorectum excision (TME). Our inclusion criteria of neoadjuvant CCRT are lower 3rd rectal cancer, stage II/III, and large (diameter >5 cm or >1/2 of circumference). Neoadjuvant concurrent CCRT had begun to apply lower 3rd rectal cancer patients or not. The radiation techniques of neoadjuvant CCRT for lower 3rd rectal cancer patients were all conventional fraction intensity modulated radiotherapy (IMRT) and concurrent fluoropyrimidine chemotherapy.Five-year overall survival rate, disease-free survival rate, and local recurrence rate for lower 3rd rectal cancer patients in group I were 51%, 45%, and 25%, respectively. On the contrary, 5-year overall survival rate, disease-free survival rate, and local recurrence rate for lower rectal cancer patients in group II were 70%, 70%, and 3%, respectively. The 5-year sphincter sparing rate was increased from 38.2% to 100% after the beginning of neoadjuvant CCRT. Analyzing local recurrence, overall survival rate, disease-specific survival rate, and sphincter sparing rate in group II were statistically significant superior to group I.Five-year overall survival rate, disease-free survival rate, and sphincter sparing rate for lower 3rd rectal cancer patients were improved after the addition of neoadjuvant CCRT. No unacceptable toxicity was noted after conventional fraction IMRT and concurrent fluoropyrimidine chemotherapy. Our study showed neoadjuvant CCRT could be valuable for lower 3rd rectal cancer patients

  20. Microstructure Modeling of 3rd Generation Disk Alloys

    NASA Technical Reports Server (NTRS)

    Jou, Herng-Jeng

    2010-01-01

    The objective of this program is to model, validate, and predict the precipitation microstructure evolution, using PrecipiCalc (QuesTek Innovations LLC) software, for 3rd generation Ni-based gas turbine disc superalloys during processing and service, with a set of logical and consistent experiments and characterizations. Furthermore, within this program, the originally research-oriented microstructure simulation tool will be further improved and implemented to be a useful and user-friendly engineering tool. In this report, the key accomplishment achieved during the second year (2008) of the program is summarized. The activities of this year include final selection of multicomponent thermodynamics and mobility databases, precipitate surface energy determination from nucleation experiment, multiscale comparison of predicted versus measured intragrain precipitation microstructure in quench samples showing good agreement, isothermal coarsening experiment and interaction of grain boundary and intergrain precipitates, primary microstructure of subsolvus treatment, and finally the software implementation plan for the third year of the project. In the following year, the calibrated models and simulation tools will be validated against an independently developed experimental data set, with actual disc heat treatment process conditions. Furthermore, software integration and implementation will be developed to provide material engineers valuable information in order to optimize the processing of the 3rd generation gas turbine disc alloys.

  1. BACODINE/3rd Interplanetary Network burst localization

    SciTech Connect

    Hurley, K.; Barthelmy, S.; Butterworth, P.; Cline, T.; Sommer, M.; Boer, M.; Niel, M.; Kouveliotou, C.; Fishman, G.; Meegan, C.

    1996-08-01

    Even with only two widely separated spacecraft (Ulysses and GRO), 3rd Interplanetary Network (IPN) localizations can reduce the areas of BATSE error circles by two orders of magnitude. Therefore it is useful to disseminate them as quickly as possible following BATSE bursts. We have implemented a system which transmits the light curves of BACODINE/BATSE bursts directly by e-mail to UC Berkeley immediately after detection. An automatic e-mail parser at Berkeley watches for these notices, determines the Ulysses crossing time window, and initiates a search for the burst data on the JPL computer as they are received. In ideal cases, it is possible to retrieve the Ulysses data within a few hours of a burst, generate an annulus of arrival directions, and e-mail it out to the astronomical community by local nightfall. Human operators remain in this loop, but we are developing a fully automated routine which should remove them, at least for intense events, and reduce turn-around times to an absolute minimum. We explain the current operations, the data types used, and the speed/accuracy tradeoffs.

  2. 3rd grade English language learners making sense of sound

    NASA Astrophysics Data System (ADS)

    Suarez, Enrique; Otero, Valerie

    2013-01-01

    Despite the extensive body of research that supports scientific inquiry and argumentation as cornerstones of physics learning, these strategies continue to be virtually absent in most classrooms, especially those that involve students who are learning English as a second language. This study presents results from an investigation of 3rd grade students' discourse about how length and tension affect the sound produced by a string. These students came from a variety of language backgrounds, and all were learning English as a second language. Our results demonstrate varying levels, and uses, of experiential, imaginative, and mechanistic reasoning strategies. Using specific examples from students' discourse, we will demonstrate some of the productive aspects of working within multiple language frameworks for making sense of physics. Conjectures will be made about how to utilize physics as a context for English Language Learners to further conceptual understanding, while developing their competence in the English language.

  3. A low energy continuous reactor separator for the production of ethanol from corn grits/starch and biomass streams. 3rd Quarterly report, October 15, 1994--January 15, 1995

    SciTech Connect

    Not Available

    1995-02-01

    This project is an attempt to develop and demonstrate an improved reactor for the production of ethanol from starch and ligno-cellulosic streams. Bio-Process Innovations holds a patent of this reactor technology, and is directing the project. A Continuous Stirred Reactor Separator (CSRS) is being built on a pilot plant scale for testing at a small Iowa ethanol plant (Permeate Refining) while bench scale tests on the reactor system are being performed at Purdue University. The project involves two industrial partners, Permeate Refining of Hopkinton, IA who will site and operate the pilot scale unit, and Lamont Sign Co, who are building the pilot scale unit. The CSRS is expected to allow the continuous conversion of various substrates to ethanol. The CSRS unit combines several operations within the confines of the reactor vessel; (1) complex carbohydrates are reduced to simple sugars by enzymatic breakdown; (2) sugars are converted to ethanol by yeast or bacteria; and (3) the ethanol is separated by a stripping gas stream. The ethanol is removed from the stripping gas in an absorber, and then taken to an extractive distillation column. This unit should allow concentrated feeds to be converted to ethanol, and the use of bottoms recycle will be extensively tested to establish the limits of minimizing net bottoms water production leaving the plant. Progress during this quarter is described.

  4. Collaborative study for the establishment of the 3rd international standard for neomycin.

    PubMed

    Rautmann, G; Daas, A; Buchheit, K-H

    2013-01-01

    An international collaborative study was organised to establish the World Health Organization (WHO) 3(rd) International Standard (IS) for neomycin. Ten laboratories from different countries participated in the collaborative study. The potency of the candidate material, a freeze-dried preparation, was estimated by microbiological assays with sensitive micro-organisms. To ensure continuity between consecutive batches, the 2(nd) IS for neomycin was used as a standard. Based on the results of the study, the 3(rd) IS for neomycin was adopted at the meeting of the WHO Expert Committee on Biological Standardization (ECBS) in 2012 with an assigned potency of 19,050 IU per vial. The 3(rd) IS for neomycin is available from the European Directorate for the Quality of Medicines & HealthCare (EDQM).

  5. 3rd year final contractor report for: U.S. Department of Energy Stewardship Science Academic Alliances Program Project Title: Detailed Measurements of Rayleigh-Taylor Mixing at Large and Small Atwood Numbers

    SciTech Connect

    Malcolm J. Andrews

    2006-04-14

    This project had two major tasks: Task 1. The construction of a new air/helium facility to collect detailed measurements of Rayleigh-Taylor (RT) mixing at high Atwood number, and the distribution of these data to LLNL, LANL, and Alliance members for code validation and design purposes. Task 2. The collection of initial condition data from the new Air/Helium facility, for use with validation of RT simulation codes at LLNL and LANL. This report describes work done in the last twelve (12) months of the project, and also contains a summary of the complete work done over the three (3) life of the project. As of April 1, 2006, the air/helium facility (Task 1) is now complete and extensive testing and validation of diagnostics has been performed. Initial condition studies (Task 2) is also comp lete. Detailed experiments with air/helium with Atwood numbers up to 0.1 have been completed, and Atwood numbers of 0.25. Within the last three (3) months we have been able to successfully run the facility at Atwood numbers of 0.5. The progress matches the project plan, as does the budget. We have finished the initial condition studies using the water channel, and this work has been accepted for publication on the Journal of Fluid Mechanics (the top fluid mechanics journal). Mr. Nick Mueschke and Mr. Wayne Kraft are continuing with their studies to obtain PhDs in the same field, and will also continue their collaboration visits to LANL and LLNL. Over its three (3) year life the project has supported two(2) Ph.D.’s and three (3) MSc’s, and produced nine (9) international journal publications, twenty four (24) conference publications, and numerous other reports. The highlight of the project has been our close collaboration with LLNL (Dr. Oleg Schilling) and LANL (Drs. Dimonte, Ristorcelli, Gore, and Harlow).

  6. Results from the UK 3rd generation programme: Albion

    NASA Astrophysics Data System (ADS)

    McEwen, R. K.; Axcell, C.; Knowles, P.; Hoade, K. P.; Wilson, M.; Dennis, P. N. J.; Backhouse, P.; Gordon, N. T.

    2008-10-01

    Following the development of 1st Generation systems in the 1970s, thermal imaging has been in service with the UK armed forces for over 25 years and has proven itself to be a battle winning technology. More recently the wider accessibility to similar technologies within opposing forces has reduced the military advantage provided by these 1st Generation systems and a clear requirement has been identified by the UK MOD for thermal imaging sensors providing increased detection, recognition and identification (DRI) ranges together with a simplified logistical deployment burden and reduced through-life costs. In late 2005, the UK MOD initiated a programme known as "Albion" to develop high performance 3rd Generation single waveband infrared detectors to meet this requirement. At the same time, under a separate programme supporting higher risk technology, a dual waveband infrared detector was also developed. The development phase of the Albion programme has now been completed and prototype detectors are now available and have been integrated into demonstration thermal imaging cameras. The Albion programme has now progressed into the second phase, incorporating both single and dual waveband devices, focussing on low rate initial production (LRIP) and qualification of the devices for military applications. All of the detectors have been fabricated using cadmium mercury telluride material (CMT), grown by metal organic vapour phase epitaxy (MOVPE) on low cost, gallium arsenide (GaAs) substrates and bump bonded to the silicon read out circuit (ROIC). This paper discusses the design features of the 3rd Generation detectors developed in the UK together with the results obtained from the prototype devices both in the laboratory and when integrated into field deployable thermal imaging cameras.

  7. PREFACE: 3rd International Conference of Mechanical Engineering Research (ICMER 2015)

    NASA Astrophysics Data System (ADS)

    Mamat, Riazalman; Rahman, Mustafizur; Mohd. Zuki Nik Mohamed, Nik; Che Ghani, Saiful Anwar; Harun, Wan Sharuzi Wan

    2015-12-01

    The 3rd ICMER2015 is the continuity of the NCMER2010. The year 2010 represents a significant milestone in the history for Faculty of Mechanical Engineering, Universiti Malaysia Pahang (UMP) Malaysia with the organization of the first and second national level conferences (1st and 2nd NCMER) at UMP on May 26-27 and Dec 3-4 2010. The Faculty then changed the name from National Conference on Mechanical Engineering Research (NCMER) to International Conference on Mechanical Engineering Research (ICMER) in 2011 and this year, 2015 is our 3rd ICMER. These proceedings contain the selected scientific manuscripts submitted to the conference. It is with great pleasure to welcome you to the "International Conference on Mechanical Engineering Research (ICMER2015)" that is held at Zenith Hotel, Kuantan, Malaysia. The call for papers attracted submissions of over two hundred abstracts from twelve different countries including Japan, Iran, China, Kuwait, Indonesia, Norway, Philippines, Morocco, Germany, UAE and more. The scientific papers published in these proceedings have been revised and approved by the technical committee of the 3rd ICMER2015. All of the papers exhibit clear, concise, and precise expositions that appeal to a broad international readership interested in mechanical engineering, combustion, metallurgy, materials science as well as in manufacturing and biomechanics. The reports present original ideas or results of general significance supported by clear reasoning and compelling evidence, and employ methods, theories and practices relevant to the research. The authors clearly state the questions and the significance of their research to theory and practice, describe how the research contributes to new knowledge, and provide tables and figures that meaningfully add to the narrative. In this edition of ICMER representatives attending are from academia, industry, governmental and private sectors. The plenary and invited speakers will present, discuss, promote and

  8. Hanford year 2000 Business Continuity Plan

    SciTech Connect

    VORNEY, S.V.

    1999-11-01

    The goal of Department of Energy Richland Operations (DOE-RL) Year 2000 (Y2K) effort is to ensure that the Hanford site successfully continues its mission as we approach and enter the 21th century. The Y2K Business Continuity Planning process provides a structured approach to identify Y2K risks to the site and to mitigate these risks through Y2K Contingency Planning, ''Zero-Day'' Transition Planning and Emergency Preparedness. This document defines the responsibilities, processes and plans for Hanford's Y2K Business Continuity. It identifies proposed business continuity drills, tentative schedule and milestones.

  9. Prediction of High School Dropout or Graduation from 3rd Grade Data.

    ERIC Educational Resources Information Center

    Lloyd, Dee Norman; Bleach, Gail

    Measures of background characteristics, school performance, and tested achievement were analyzed for four race-by-sex samples of 3rd graders who were known to have later become high school dropouts or graduates. Results showed that as early as five to eight years before leaving school, dropouts differed significantly from graduates in age, tested…

  10. Peace Corps. 3rd Annual Report.

    ERIC Educational Resources Information Center

    Peace Corps, Washington, DC.

    Projects, operations, and future plans are covered in this annual report for the third year of the Peace Corps. An introduction comments on returning volunteers and presents regional maps with tables for Latin America, Africa, Near East and South Asia, and Far East. Section 1 contains letters and reports from volunteers in Peru, Ivory Coast,…

  11. Beyond 3rd generation MCT: SXGA QWIP (Invited Paper)

    NASA Astrophysics Data System (ADS)

    Crawford, Stewart; Skivington, Tracey; Craig, Robert; Haining, Andrew; Costard, Eric; Belhaire, Eric; Bois, Philippe

    2005-05-01

    Successful past experience of implementing long wave MCT 1st and 2nd Generation thermal imagers has demonstrated to THALES Optronics that MCT presents difficult challenges when correcting non-uniformity errors caused by rapidly changing detector element gain and offset drifts. These problems become even more demanding when the move is made from long linear arrays to focal plane arrays due to the significantly larger number of detector elements. Relaxation of these demands would make a significant impact on the price/performance trade which inevitably occurs in a camera development. In recognition of the need to offer UK MOD best value, THALES Optronics has initiated a programme to achieve a SXGA resolution camera and is working with UK MOD, over a two year period, to investigate whether an alternative technology can maintain the high resolution required whilst achieving a downward step change in price. The selected technology is 3rd Generation Gallium Arsenide long wave Quantum Well Infra-red Photodiode (QWIP) chosen because initial indications are that drift rates are orders of magnitude slower than MCT. The programme involves studies to determine effects of defect clusters, bimodalism, non-uniformity correction levels and higher than normal operating temperatures on achieving acceptable performance, including logistics, in user scenarios whilst maximising detector yield. Development of demonstrator IR camera hardware (technology readiness level 6/7) based on a THALES Research & Technology QWIP array is also part of the programme.

  12. Presenting the 3rd edition of WRB

    NASA Astrophysics Data System (ADS)

    Schad, Peter

    2014-05-01

    The third edition of the international soil classification system "World Reference Base for Soil Resources" (WRB) will be presented during der 20th World Congress of Soil Science, Jeju, Korea, June 9-12. The second edition was published in 2006 and the first in 1998, which, in turn, was based on the Legends of the FAO Soil Map of the World. Now, after eight years of experience with the second edition, time was due for a revision. The major changes are: 1. The second edition had two different qualifier sequences for naming soils (IUSS Working Group WRB, 2006, update 2007) and for creating map legends (Guidelines for creating small-scale map legends using the WRB; IUSS Working Group WRB, 2010). The third edition has one sequence for both. The qualifiers for every Reference Soil Group are subdivided into a small number of main qualifiers that are ranked and a larger number of additional qualifiers that are not ranked and given in an alphabetical order. The name of a pedon must comprise all applying qualifiers. The name of a map unit comprises a specified small number of main qualifiers, depending on scale, whereas all other qualifiers are optional. 2. For some soils, problems have been reported. Albeluvisols are difficult to detect in the field and cover only small surfaces. They have been replaced by Retisols, which have a broader definition that is easier to identify in the field. 3. The use of some diagnostics was difficult. Examples are: The argic horizon had too low limit values, so we had much more soils with argic horizons than justified. The definitions of the cambic horizon and the gleyic and stagnic properties were not precise enough. Organic material, mollic and umbric horizons had an unnecessary complicated definition. 4. Some changes in the key to the Reference Soil Groups seemed to be justified. Fluvisols were moved further down, Durisols and Gypsisols switched their position, also Arenosols and Cambisols. The soils with an argic horizon were brought

  13. GEOSCOPE network : continuous recording over 29 years

    NASA Astrophysics Data System (ADS)

    Pardo, C.; Bonaime, S.; Stutzmann, E.; Maggi, A.; Team, G.; Geoscope Team

    2011-12-01

    The GEOSCOPE observatory was created in 1982 and has now provided the scientific community with nearly 30 years of continuous broadband recordings . The 33 GEOSCOPE stations are installed in 19 countries, across all continents and on islands throughout the oceans. They are equipped with three component very broadband seismometers (STS1 or STS2) and 24 or 26 bit digitizers. Progressively stations are being equipped with warpless base plates which decrease long period noise on horizontal components by up to 15dB. In most stations, a pressure gauge and a thermometer are also installed. In 2011, 3 stations have been upgraded: COYC and PEL in Chile and ATD in Djibouti. Two new stations have been installed in Ivituut (station IVI, Greenland, GLISN project) and in Vanuatu islands (station SANVU). Currently, 27 stations transmit data in real or near real time to the GEOSCOPE Data Center and to tsunami warning centers. Continuous data from all stations are collected by the GEOSCOPE Data Center in Paris where they are validated, archived and made available to the international scientific community. Data are freely available to users via different interfaces according to data type (http://geoscope.ipgp.fr). We provide continuous data in real time through the seedlink protocol, validated continuous waveforms through the NetDC system and Data Handler Interface, a selection of large earthquake seismograms through the geoscope web portal. GEOSCOPE/IPGP is one of the four primary nodes of EIDA (European Integrated Data Archive) and our data are accessible through (http://www.seismicportal.eu). Noise levels for the last 20 years of continuous data are also accessible via the geoscope web site. Stations in both hemispheres show stronger noise amplitude during local winter except for the station DRV which is surrounded by sea ice in winter.

  14. PREFACE: 3rd International Congress on Mechanical Metrology (CIMMEC2014)

    NASA Astrophysics Data System (ADS)

    2015-10-01

    From October 14th to 16th 2014, The Brazilian National Institute of Metrology, Quality, and Technology (Inmetro) and the Brazilian Society of Metrology (SBM) organized the 3rd International Congress on Mechanical Metrology (3rd CIMMEC). The 3rd CIMMEC was held in the city of Gramado, Rio Grande do Sul, Brazil. Anticipating the interest and enthusiasm of the technical-scientific community, the Organizing Institutions invite people and organizations to participate in this important congress, reiterating the commitment to organize an event according to highest international standards. This event has been conceived to integrate people and organizations from Brazil and abroad in the discussion of advanced themes in metrology. Manufacturers and dealers of measuring equipment and standards, as well as of auxiliary accessories and bibliographic material, had the chance to promote their products and services in stands at the Fair, which has taken place alongside the Congress. The 3rd CIMMEC consisted of five Keynote Speeches and 116 regular papers. Among the regular papers, the 25 most outstanding ones, comprising a high quality content on Mechanical Metrology, were selected to be published in this issue of Journal of Physics: Conference Series. It is our great pleasure to present this volume of Journal of Physics: Conference Series to the scientific community to promote further research in Mechanical Metrology and related areas. We believe that this volume will be both an excellent source of scientific material in the fast evolving fields that were covered by CIMMEC 2014.

  15. 75 FR 55313 - Record of Decision (ROD) for Conversion of the 3rd Armored Cavalry Regiment (3rd ACR) to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... 3rd ACR at Fort Hood is being selected because the unit will have maximum time to convert and train... required for an SBCT, and has adequate maneuver space to accommodate SBCT training. The 3rd ACR will...

  16. 3rd Workshop on Semantic Ambient Media Experience (SAME) - In Conjunction with AmI-2010

    NASA Astrophysics Data System (ADS)

    Lugmayr, Artur; Stockleben, Bjoern; Kaario, Juha; Pogorelc, Bogdan; Risse, Thomas

    The SAME workshop takes place for the 3rd time in 2010, and it's theme in this year was creating the business value-creation, vision, media theories and technology for ambient media. SAME differs from other workshops due to its interactive and creative touch and going beyond simple powerpoint presentations. Several results will be published by AMEA - the AMbient Media Association (www.ambientmediaassociation.org.

  17. The 3rd Annual Controlled Structures Technology Symposium

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Viewgraphs of presentations at the Controlled Structures Technology (CST) MIT Space Engineering Research Center 3rd Annual Symposium are included. Topics covered include optical interferometer testbed; active impedence matching of complex structural systems; application of CST to adaptive optics; middeck 0-G dynamics Experiment (MODE); inhibiting multiple mode vibration in controlled flexible systems; the middeck active control experiment (MACE); robust control for uncertain structures; cost averaging techniques for robust structural control; and intelligent structures technology.

  18. PREFACE: 3rd International Symposium ''Optics and its Applications''

    NASA Astrophysics Data System (ADS)

    Calvo, M. L.; Dolganova, I. N.; Gevorgyan, N.; Guzman, A.; Papoyan, A.; Sarkisyan, H.; Yurchenko, S.

    2016-01-01

    The SPIE.FOCUS Armenia: 3rd International Symposium ''Optics and its Applications'' (OPTICS-2015) http://rau.am/optics2015/ was held in Yerevan, Armenia, in the period October 1 - 5, 2015. The symposium was organized by the International Society for Optics and Photonics (SPIE), the Armenian SPIE student chapter with collaboration of the Armenian TC of ICO, the Russian-Armenian University (RAU), the Institute for Physical Research of National Academy of Sciences of Armenia (IPR of NAS), the Greek-Armenian industrial company LT-PYRKAL, and the Yerevan State University (YSU). The Symposium was co-organized by the SPIE & OSA student chapters of BMSTU, the Armenian OSA student chapter, and the SPIE student chapters of Lund University and Wroclaw University of Technology. The symposium OPTICS-2015 was dedicated to the International Year of Light and Light-Based Technologies. OPTICS-2015 was devoted to modern topics and optical technologies such as: optical properties of nanostructures, silicon photonics, quantum optics, singular optics & its applications, laser spectroscopy, strong field optics, biomedical optics, nonlinear & ultrafast optics, photonics & fiber optics, and mathematical methods in optics. OPTICS-2015 was attended by 100 scientists and students representing 17 countries: Armenia, China, Czech Republic, France, Georgia, Germany, India, Iran, Italy, Latvia, Mexico, Poland, Russia, Saudi Arabia, Sweden, Ukraine, and USA. Such a broad international community confirmed the important mission of science to be a uniting force between different countries, religions, and nations. We hope that OPTICS-2015 inspired and motivated students and young scientists to work in optics and in science in general. The present volume of Journal of Physics: Conference Series includes proceedings of the symposium covering various aspects of modern problems in optics. We are grateful to all people who were involved in the organization process. We gratefully acknowledge support from

  19. [Modern surgical treatment of breast cancer. 3rd Breast Cancer Consensus Conference].

    PubMed

    Lázár, György; Bursics, Attila; Farsang, Zoltán; Harsányi, László; Kósa, Csaba; Maráz, Róbert; Mátrai, Zoltán; Paszt, Attila; Pavlovics, Gábor; Tamás, Róbert

    2016-09-01

    Therapy for breast cancer today is characterised by ever more precise diagnostic methods and ever more effective oncological treatments, a trend which will certainly continue into the future. Breast preservation and the application of oncoplastic principles are increasingly popular. A sentinel lymph node biopsy in the surgical treatment of the axilla is primary, with the indication for axillary block dissection (ABD) narrowing and radiation therapy becoming an alternative to ABD in certain cases. This publication summarises our recommendations on the surgical treatment of breast cancer based on the content of the 3rd Breast Cancer Consensus Conference and considering the latest international studies and professional recommendations. PMID:27644928

  20. The Power of PreK-3rd: How a Small Foundation Helped Push Washington State to the Forefront of the PreK-3rd Movement. FCD Case Study

    ERIC Educational Resources Information Center

    Nyhan, Paul

    2011-01-01

    The New School Foundation was not born from a commission, legislative mandate, research project, think tank, or even the mind of a leading education scholar. One of Washington state's pioneering PreK-3rd initiatives began as the brainchild of a wealthy Seattle businessman, Stuart Sloan, 20 years ago. The New School Foundation and its ideas were…

  1. Precipitation Model Validation in 3rd Generation Aeroturbine Disc Alloys

    NASA Technical Reports Server (NTRS)

    Olson, G. B.; Jou, H.-J.; Jung, J.; Sebastian, J. T.; Misra, A.; Locci, I.; Hull, D.

    2008-01-01

    In support of application of the DARPA-AIM methodology to the accelerated hybrid thermal process optimization of 3rd generation aeroturbine disc alloys with quantified uncertainty, equilibrium and diffusion couple experiments have identified available fundamental thermodynamic and mobility databases of sufficient accuracy. Using coherent interfacial energies quantified by Single-Sensor DTA nucleation undercooling measurements, PrecipiCalc(TM) simulations of nonisothermal precipitation in both supersolvus and subsolvus treated samples show good agreement with measured gamma particle sizes and compositions. Observed longterm isothermal coarsening behavior defines requirements for further refinement of elastic misfit energy and treatment of the parallel evolution of incoherent precipitation at grain boundaries.

  2. Test Review: C. Keith Conners "Conners 3rd Edition" Toronto, Ontario, Canada--Multi-Health Systems, 2008

    ERIC Educational Resources Information Center

    Kao, Grace S.; Thomas, Hillary M.

    2010-01-01

    "Conners 3rd Edition" is the most updated version of a series of measures for assessing attention deficit hyperactivity disorder (ADHD) and common comorbid problems/disorders in children and adolescents ranging from 6 to 18 years of age. Related problems that the test helps assess include executive dysfunction, learning problems, aggression, and…

  3. Predicting 3rd Grade and 10th Grade FCAT Success for 2006-07. Research Brief. Volume 0601

    ERIC Educational Resources Information Center

    Froman, Terry; Rubiera, Vilma

    2006-01-01

    For the past few years the Florida School Code has set the Florida Comprehensive Assessment Test (FCAT) performance requirements for promotion of 3rd graders and graduation for 10th graders. Grade 3 students who do not score at level 2 or higher on the FCAT SSS Reading must be retained unless exempted for special circumstances. Grade 10 students…

  4. Predicting 3rd Grade and 10th Grade FCAT Success for 2007-08. Research Brief. Volume 0702

    ERIC Educational Resources Information Center

    Froman, Terry; Rubiera, Vilma

    2008-01-01

    For the past few years the Florida School Code has set the Florida Comprehensive Assessment Test (FCAT) performance requirements for promotion of 3rd graders and graduation for 10 graders. Grade 3 students who do not score at level 2 or higher on the FCAT SSS Reading must be retained unless exempted for special circumstances. Grade 10 students…

  5. Iowa Acceleration Scale Manual: A Guide for Whole-Grade Acceleration K-8. (3rd Edition, Manual)

    ERIC Educational Resources Information Center

    Assouline, Susan G.; Colangelo, Nicholas; Lupkowski-Shoplik, Ann; Forstadt, Leslie; Lipscomb, Jonathon

    2009-01-01

    Feedback from years of nationwide use has resulted in a 3rd Edition of this unique, systematic, and objective guide to considering and implementing academic acceleration. Developed and tested by the Belin-Blank Center at the University of Iowa, the IAS ensures that acceleration decisions are systematic, thoughtful, well reasoned, and defensible.…

  6. Continuing Education in Alabama after One Year.

    ERIC Educational Resources Information Center

    Dutton, Donnie; And Others

    Statistical data are presented on the attitudes, opinions, and participation patterns of 291 Alabama public health workers involved during the 1967-68 in statewide professional continuing education programs. Reactions to program components (instructional television, study manuals, group discussion sessions) and specific topics are summarized. Item…

  7. Designing a 3rd generation, authenticatable attribute measurement system

    SciTech Connect

    Thron, Jonathan; Karpius, Peter; Santi, Peter; Smith, Morag; Vo, Duc; Williams, Richard

    2009-01-01

    Attribute measurement systems (AMS) are designed to measure potentially sensitive items containing Special Nuclear Materials to determine if the items possess attributes which fall within an agreed-upon range. Such systems could be used in a treaty to inspect and verify the identity of items in storage without revealing any sensitive information associated with the item. An AMS needs to satisfy two constraints: the host party needs to be sure that none of their sensitive information is released, while the inspecting party wants to have confidence that the limited amount of information they see accurately reflects the properties of the item being measured. The former involves 'certifying' the system and the latter 'authenticating' it. Previous work into designing and building AMS systems have focused more on the questions of certifiability than on the questions of authentication - although a few approaches have been investigated. The next step is to build a 3rd generation AMS which (1) makes the appropriate measurements, (2) can be certified, and (3) can be authenticated (the three generations). This paper will discuss the ideas, options, and process of producing a design for a 3rd generation AMS.

  8. The development of 3rd generation IR detectors at AIM

    NASA Astrophysics Data System (ADS)

    Ziegler, J.; Eich, D.; Mahlein, M.; Schallenberg, T.; Scheibner, R.; Wendler, J.; Wenisch, J.; Wollrab, R.; Daumer, V.; Rehm, R.; Rutz, F.; Walther, M.

    2011-06-01

    3rd generation IR modules - dual-color (DC), dual-band (DB), and large format two-dimensional arrays - require sophisticated production technologies such as molecular beam epitaxy (MBE) as well as new array processing techniques, which can satisfy the rising demand for increasingly complex device structures and low cost detectors. AIM will extend its future portfolio by high performance devices which make use of these techniques. The DC MW / MW detectors are based on antimonide type-II superlattices (produced by MBE at Fraunhofer IAF, Freiburg) in the 384x288 format with a 40 μm pitch. For AIM, the technology of choice for MW / LW DB FPAs is MCT MBE on CdZnTe substrates, which has been developed in cooperation with IAF, Freiburg. 640x512, 20 μm pitch Focal Plane Arrays (FPAs) have been processed at AIM. The growth of MW MCT MBE layers on alternate substrates is challenging, but essential for competitive fabrication of large two-dimensional arrays such as megapixel (MW 1280x1024, 15 μm pitch) FPAs. This paper will present the development status and latest results of the above-mentioned 3rd Gen FPAs and Integrated Detector Cooler Assemblies (IDCAs).

  9. Development of the 3rd Generation ECR ion source

    SciTech Connect

    Lyneis, C.M.; Xie, Z.Q.; Taylor, C.E.

    1997-09-01

    The LBNL 3rd Generation ECR ion source has progressed from a concept to the fabrication of a full scale prototype superconducting magnet structure. This new ECR ion source will combine the recent ECR ion source techniques that significantly enhance the production of high charge state ions. The design includes a plasma chamber made from aluminum to provide additional cold electrons, three separate microwave feeds to allow multiple-frequency plasma heating (at 10, 14 and 18 GHz or at 6, 10 and 14 GHz) and very high magnetic mirror fields. The design calls for mirror fields of 4 T at injection and 3 T at extraction and for a radial field strength at the wall of 2.4 T. The prototype superconducting magnet structure which consists of three solenoid coils and six race track coils with iron poles forming the sextupole has been tested in a vertical dewar. After training, the sextupole magnet reached 105% of its design current with the solenoids off. With the solenoids operating at approximately 70% of their full design field, the sextuple coils operated at 95% of the design value which corresponds to a sextupole field strength at the plasma wall of more than 2.1 T.

  10. 80. GENERAL VIEW TO NORTH ON 3RD AVENUE EL AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    80. GENERAL VIEW TO NORTH ON 3RD AVENUE EL AT GUN HILL STATION. 7TH AVENUE EL EXPRESS IS VISIBLE ABOVE THE 3RD AVENUE EL WHICH JOINED ONTO THE SAME STRUCTURE AT GUN HILL ROAD. NOTE: GUN HILL ROAD IS THE NORTH TERMINUS OF THE 3RD AVENUE ELEVATED. TRAINS DID NOT CARRY PASSENGERS BEYOND THIS POINT, ALTHOUGH THE 3RD AVENUE TRACK DID EXTEND FURTHER NORTH FOR SWITCHING PURPOSES AND INTO THE YARDS. - Interborough Rapid Transit Company, Third Avenue Elevated Line, Borough of the Bronx, New York County, NY

  11. The effect of surgical technique on lingual nerve damage during lower 3rd molar removal by dental students.

    PubMed

    Robinson, P P; Loescher, A R; Smith, K G

    1999-05-01

    We have previously shown that avoidance of lingual flap retraction with a Howarth periosteal elevator during lower 3rd molar removal, reduces the incidence of lingual nerve damage. In that study, the surgery was undertaken by qualified staff and we have now assessed the effect of revising the method taught to our junior undergraduate dental students. We evaluated the outcome of surgery undertaken by 2 consecutive years of students, each group being taught 1 of the 2 methods. A total of 200 patients requiring lower 3rd molar removal under local anaesthesia were included in the study. In year 1, the surgery included elevation of a lingual flap and insertion of a Howarth elevator adjacent to the lingual plate; in year 2 this part of the procedure was avoided by using a purely buccal approach. There were no significant differences between the levels of tooth eruption and types of impaction of the teeth removed in each year. Lingual sensory disturbance occurred in 3 patients in the 'flap' group (3.3%) and in 1 patient (0.9%) in the 'no flap' group. As this incidence is not significantly different in the 2 groups (P < 0.4), we conclude that avoidance of lingual retraction by students undertaking lower 3rd molar removal does not appear to place the lingual nerve at greater risk. In view of the results of our previous study, we therefore advocate this method for use in undergraduate dental education. PMID:10530161

  12. Design of the 3rd generation ECR ion source

    SciTech Connect

    Lyneis, C.M.; Xie, Z.Q.; Taylor, C.E.

    1997-02-01

    Development of the 3rd Generation ECR ion source has progressed from a concept described in the last ECR Ion Source Workshop to the fabrication of a full scale prototype superconducting magnet structure. The prototype consists of three solenoid coils and six race track coils with iron poles forming the sextupole. The design calls for mirror fields of 4 T at injection and 3 T at extraction and for a radial field strength at the wall of 2.4 T. The prototype magnet will be tested this spring in an existing vertical cryostat to determine its operating characteristics including maximum operating values, training characteristics and to study the interaction between the solenoid and sextupole coils. Design of the ECR plasma chamber includes aluminum walls to provide an enhanced source of cold electrons, up to three separate microwave feeds to allow simultaneous heating of the plasma electrons at 10, 14 and 18 GHz or at 6, 10 and 14 GHz. Water cooling of the plasma chamber walls and the injection and extraction plates is planned so that up to 10 kW of microwave power can be used without excessive heating of the chamber components. Experience with the AECR-U at LBNL shows that increasing the magnetic fields and using two frequency heating allows operation at lower neutral pressures and higher microwave power density. Both of these conditions are needed to produce very high charge states from elements with masses greater than xenon and the resulting higher energy, more intense heavy beams from the 88-Inch Cyclotron would provide new research opportunities.

  13. John D. Rockefeller 3rd, statesman and founder of the Population Council.

    PubMed

    Dunlop, J

    2000-01-01

    This article presents a profile of John D. Rockefeller 3rd, statesman and founder of the Population Council. It is noted that Rockefeller took a broad view of population control as a means to address poverty and economic development rather than as an end in itself. In 1952 he initiated the convocation of the Conference on Population Problems held in Williamsburg, Virginia. The discussion focused on food supply, industrial development, depletion of natural resources, and political instability resulting from unchecked population growth. In 1967, Rockefeller initiated, lobbied for, and finally achieved a World Leaders' Statement signed by 30 heads of state including US President Lyndon Johnson. The document drew attention to population growth as a world problem and engendered political support for family planning as a solution. After 3 years the Commission on Population Growth and the American Future was established, and Rockefeller was made its chairman. Several issues were debated, including more safer fertility control and the legalization of abortion.

  14. Additional circular intercostal space created by bifurcation of the left 3rd rib and its costal cartilage: a case report

    PubMed Central

    2013-01-01

    Introduction In the thorax there are normally 11 pairs of intercostal spaces: the spaces between adjacent ribs. The intercostal spaces contain intercostal muscles, intercostal nerves and vessels. Case presentation During a routine dissection for undergraduate medical students, we observed a variation involving the left 3rd rib and 3rd costal cartilage in the cadaver of a man of Indian ethnicity aged about 65 years. The left 3rd rib and its costal cartilage were bifurcated at their costochondral junction enclosing a small circular additional intercostal space. Muscle tissue covered by deep fascia was present in this circular intercostal space. The muscle in the circular intercostal space received its nerve supply from a branch of the 2nd intercostal nerve. Conclusions Knowledge of such variations is helpful to surgeons operating on the anterior thoracic wall involving ribs and intercostal spaces. Knowing the possibility of the presence of an additional space between normal intercostal spaces can guide a surgeon through to a successful surgery. PMID:23298541

  15. 3rd Annual NASA Ames Space Science and Astrobiology Jamboree

    NASA Technical Reports Server (NTRS)

    Dotson, Jessie

    2015-01-01

    The Space Science and Astrobiology Division at NASA Ames Research Center consists of over 50 civil servants and more than 110 contractors, co-­-ops, post-­-docs and associates. Researchers in the division are pursuing investigations in a variety of fields including exoplanets, planetary science, astrobiology and astrophysics. In addition, division personnel support a wide variety of NASA missions including (but not limited to) Kepler, SOFIA, LADEE, JWST, and New Horizons. With such a wide variety of interesting research going on, distributed among three branches in at least 5 different buildings, it can be difficult to stay abreast of what one's fellow researchers are doing. Our goal in organizing this symposium is to facilitate communication and collaboration among the scientists within the division, and to give center management and other ARC researchers and engineers an opportunity to see what scientific research and science mission work is being done in the division. We are also continuing the tradition within the Space Science and Astrobiology Division to honor one senior and one early career scientist with the Pollack Lecture and the Early Career Lecture, respectively. With the Pollack Lecture, our intent is to select a senior researcher who has made significant contributions to any area of research within the space sciences, and we are pleased to honor Dr. William Borucki this year. With the Early Career Lecture, our intent is to select a young researcher within the division who, by their published scientific papers, shows great promise for the future in any area of space science research, and we are pleased to honor Dr. Melinda Kahre this year

  16. Midwest Child-Parent Center (CPC) PreK-3rd Grade School Reform Model: Impacts on Child and Family Outcomes over Time

    ERIC Educational Resources Information Center

    Gaylor, Erika; Spiker, Donna; Wei, Xin; Lease, Erin; Reynolds, Arthur

    2015-01-01

    This presentation reports on the goals and preliminary outcomes of the Child-Parent Centers (CPC) Expansion Project, which is a PreK to 3rd grade school reform model aimed at improving the short- and long-term outcomes of participating children and families. The model provides continuous education and family support services to schools serving a…

  17. PREFACE: 3rd International Congress on Ceramics (ICC3)

    NASA Astrophysics Data System (ADS)

    Niihara, Koichi; Ohji, Tatsuki; Sakka, Yoshio

    2011-10-01

    Early in 2005, the American Ceramic Society, the European Ceramic Society and the Ceramic Society of Japan announced a collaborative effort to provide leadership for the global ceramics community that would facilitate the use of ceramic and glass materials. That effort resulted in an agreement to organize a new biennial series of the International Congress on Ceramics, convened by the International Ceramic Federation (ICF). In order to share ideas and visions of the future for ceramic and glass materials, the 1st International Congress on Ceramics (ICC1) was held in Canada, 2006, under the organization of the American Ceramic Society, and the 2nd Congress (ICC2) was held in Italy, 2008, hosted by the European Ceramic Society. Organized by the Ceramic Society of Japan, the 3rd Congress (ICC3) was held in Osaka, Japan, 14-18 November 2010. Incorporating the 23rd Fall Meeting of the Ceramic Society of Japan and the 20th Iketani Conference, ICC3 was also co-organized by the Iketani Science and Technology Foundation, and was endorsed and supported by ICF, Asia-Oceania Ceramic Federation (AOCF) as well as many other organizations. Following the style of the previous two successful Congresses, the program was designed to advance ceramic and glass technologies to the next generation through discussion of the most recent advances and future perspectives, and to engage the worldwide ceramics community in a collective effort to expand the use of these materials in both conventional as well as new and exciting applications. ICC3 consisted of 22 voluntarily organized symposia in the most topical and essential themes of ceramic and glass materials, including Characterization, design and processing technologies Electro, magnetic and optical ceramics and devices Energy and environment related ceramics and systems Bio-ceramics and bio-technologies Ceramics for advanced industry and safety society Innovation in traditional ceramics It also contained the Plenary Session and the

  18. Geysers Characteristics before and after Landslide of June 3-rd, 2007 (Geysers Valley, Kamchatka, Russia)

    NASA Astrophysics Data System (ADS)

    Droznin, V. A.; Kiryukhin, A. V.; Muraviev, J. D.

    2007-12-01

    Since 1990 cycling characteristics of five geysers (Maly, Bolshoy, Shel, Velican, Troynoy) were contentiously monitoring using automatic telemetric system (V A Drosnin, http://www.ch0103.emsd.iks.ru/ ). The most powerful geyser Velikan erupted steam clouds at 300 m height. 1:20 UTC June 3-rd, 2007 lower basin of the Geysers Valley was in a few minutes buried under 10 mln m3 of mud, debris, and blocks of rocks. Some indications were found, that landslide triggered by steam eruption in the upstream area of Vodopadny creek. As a result of this three famous geysers (Pervenets, Sakharny,Troynoy) located at lower elevations were sealed under 10-30 m thick caprock as well as Vodopadny hot creek, a rock dumb trap Geysernaya river and lifted water into 20 m deep lake, which flooded three famous geysers (Conus, Bolshoy and Maly) terminating their cycling activity. Nevertheless Bolshoy and Maly activity continues in a form of discharge of water circulated in the former geysers channels and a clear plume at a lake surface above exits observed. Shortly after landslide continuous monitoring of the cycling characteristics of the upper basin geysers, including Velikan and lake level, accomplished by temperature loggers - restarted. There are some indications time periods of the geysers cycling decrease.

  19. 1. WEST SIDE AND ENTRY, FROM ACROSS 3RD STREET, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. WEST SIDE AND ENTRY, FROM ACROSS 3RD STREET, LOOKING EAST. - Oakland Naval Supply Center, Administration Building-Dental Annex-Dispensary, Between E & F Streets, East of Third Street, Oakland, Alameda County, CA

  20. Survey of K-3rd-Grade Teachers' Knowledge of Ear Infections and Willingness to Participate in Prevention Programs

    ERIC Educational Resources Information Center

    Danhauer, Jeffrey L.; Johnson, Carole E.; Caudle, Abby T.

    2011-01-01

    Purpose: Ear infections are prevalent in kindergarten through 3rd-grade (K-3rd) children and can affect their performance at school. Chewing gum, when administered by parents and teachers, can help prevent ear infections in children. This pilot study surveyed K-3rd-grade teachers in the Santa Barbara School Districts to assess their knowledge…

  1. Teaching Low Achieving and Disadvantaged Students, 3rd Edition

    ERIC Educational Resources Information Center

    Hargis, Charles H.

    2006-01-01

    This new edition updates and expands the previous volume and continues to reflect the concepts and the reasons behind learning and behavior problems of low achieving and disadvantaged students. Through the chapters, the author describes instructional levels and independent levels, emphasizing that success is produced by finding the place on the…

  2. Textbook of Child and Adolescent Psychiatry. 3rd Edition.

    ERIC Educational Resources Information Center

    Wiener, Jerry M.; Dulcan, Mina K.

    The third edition of this textbook continues its tradition of integrating clinical wisdom and scientific research to improve patient care and advocacy for children and families. Each of the 56 chapters presents a summary of a core topic, blending clinical experience with evidence-based practices in assessment and treatment. Divided into 10 parts,…

  3. EMSL Quarterly Highlights Report: FY 2008, 3rd Quarter

    SciTech Connect

    Showalter, Mary Ann

    2008-09-16

    The EMSL Quarterly Highlights Report covers the science, staff and user recognition, and publication activities that occurred during the 1st quarter (October 2007 - December 2007) of Fiscal Year 2008.

  4. [3rd Hungarian Breast Cancer Consensus Conference - Surgery Guidelines].

    PubMed

    Lázár, György; Bursics, Attila; Farsang, Zoltán; Harsányi, László; Kósa, Csaba; Maráz, Róbert; Mátrai, Zoltán; Paszt, Attila; Pavlovics, Gábor; Tamás, Róbert

    2016-09-01

    Therapy for breast cancer today is characterised by ever more precise diagnostic methods and ever more effective oncological treatments, a trend which will certainly continue in the future. Breast preservation and the application of oncoplastic principles are increasingly popular. A sentinel lymph node biopsy in the surgical treatment of the axilla is primary, with the indication for axillary block dissection (ABD) narrowing and radiation therapy becoming an alternative to ABD in certain cases. This publication summarises our recommendations on the surgical treatment of breast cancer based on the content of the 2nd Breast Cancer Consensus Conference and considering the latest international studies and professional recommendations. PMID:27579720

  5. IVHM for the 3rd Generation RLV Program: Technology Development

    NASA Technical Reports Server (NTRS)

    Kahle, Bill

    2000-01-01

    The objective behind the Integrated Vehicle Health Management (IVHM) project is to develop and integrate the technologies which can provide a continuous, intelligent, and adaptive health state of a vehicle and use this information to improve safety and reduce costs of operations. Technological areas discussed include: developing, validating, and transfering next generation IVHM technologies to near term industry and government reusable launch systems; focus NASA on the next generation and highly advanced sensor and software technologies; and validating IVHM systems engineering design process for future programs.

  6. Growth and mineral nutrition of field crops 3rd Edition

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Green revolution technology of last century led to increased production. The green revolution, however, did not link farming system sustainability to food system sustainability as a whole. In recent years the rate of food-grain production has been lower than the rate of population growth. This will ...

  7. NS&T Management Observations - 3rd Quarter

    SciTech Connect

    David Gianotto

    2014-07-01

    The INL Management Observation Program (MOP) is designed to improve managers and supervisors understanding of work being performed by employees and the barriers impacting their success. The MOP also increases workers understanding of managements’ expectations as they relate to safety, security, quality, and work performance. Management observations are designed to improve the relationship and trust between employees and managers through increased engagement and interactions between managers and researchers in the field. As part of continuous improvement, NS&T management took initiative to focus on the participation and quality of observations in FY 14. This quarterly report is intended to (a) summarize the participation and quality of management’s observations, (b) assess observations for commonalities or trends related to facility or process barriers impacting research, and (c) provide feedback and make recommendations for improvements NS&T’s MOP.

  8. Ectopic 3rd molar tooth in the maxillary antrum.

    PubMed

    Bello, Seidu A; Oketade, Ifeoluwa O; Osunde, Otasowie D

    2014-01-01

    Location of ectopic tooth in a nondentate area like the maxillary antrum is rare. A 17-year-old boy, with one year history of recurrent right facial swelling and radiographic finding of a maxillary third molar tooth located at the posterior wall of the maxillary antrum, is presented. Under endotracheal intubation, the tooth was extracted through a Caldwell-Luc antrostomy approach and patient had an uneventful recovery and has been symptom free for eight months. Ectopic tooth in the maxillary antrum is rare and is commonest with maxillary third molar. It may be symptomless but is more commonly associated with inflammatory symptoms. The treatment of choice is surgical excision which is mostly carried out with Caldwell-Luc approach, even though endoscopic approach is being reported. PMID:25132999

  9. SESAME-A 3rd Generation Synchrotron Light Source for the Middle East

    NASA Astrophysics Data System (ADS)

    Winick, Herman

    2010-02-01

    Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research center in construction in Jordan. It will enable world class research by scientists from the region, reversing the brain drain. It will also build bridges between diverse societies, contributing to a culture of peace through international cooperation in science. The centerpiece is a synchrotron light source originating from BESSY I, a gift by Germany. The upgraded machine, a 2.5 GeV 3rd Generation Light Source (133m circumference, 26nm-rad emittance and 12 places for insertion devices), will provide light from infra-red to hard X-rays, offering excellent opportunities to train local scientists and attract those working abroad to return. The SESAME Council meets twice each year and presently has nine Members (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority, Turkey). Members have responsibility for the project and provide the annual operations budget (1.5M US dollars in 2009, expected to rise to about 5M when operation starts in 2012-13). Jordan provided the site, building, and infrastructure. A staff of 20 is installing the 0.8 GeV BESSY I injection system. The facility will have the capacity to serve 30 or more experiments operating simultaneously. See www.sesame.org.jo )

  10. PREFACE: 3rd International Conference on Manufacturing, Optimization, Industrial and Material Engineering (MOIME 2015)

    NASA Astrophysics Data System (ADS)

    Lumban Gaol, Ford; Webb, Jeff; Ding, Jun

    2015-05-01

    The 3rd International Conference on Manufacturing, Optimization, Industrial and Material Engineering (MOIME 2015) was held at the Sheraton Kuta, Bali, Indonesia, from 28 - 29 March 2015. The MOIME 2015 conference is aimed to bring together researchers, engineers and scientists in the domain of interest from around the world. MOIME 2015 is placed on promoting interaction between the theoretical, experimental, and applied communities, so that a high level exchange is achieved in new and emerging areas within Material Engineering, Industrial Engineering and all areas that relate to Optimization. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program, as well as the invited and plenary speakers. This year, we received 99 papers and after rigorous review, 24 papers were accepted. The participants come from eight countries. There were four parallel sessions and two invited speakers. It is an honour to present this volume of IOP Conference Series: Materials Science and Engineering (MSE) and we deeply thank the authors for their enthusiastic and high-grade contributions. Finally, we would like to thank the conference chairmen, the members of the steering committee, the organizing committee, the organizing secretariat and the financial support from the conference sponsors that allowed the success of MOIME 2015. The Editors of the MOIME 2015 Proceedings Dr. Ford Lumban Gaol Jeff Webb, Ph.D Prof. Jun DING, Ph.D

  11. [Infant Mortality in Argentina: reducibility criteria, 3rd review].

    PubMed

    Finkelstein, Juliana Zoe; Duhau, Mariana; Abeyá Gilardon, Enrique; Ferrario, Claudia; Speranza, Ana; Asciutto, Carolina; Marconi, Élida; Guevel, Carlos; Fernández, María de las Mercedes; Martínez, María Laura; Santoro, Adrián; Loiacono, Karina; Lomuto, Celia

    2015-08-01

    The infant mortality rate is an indicator of quality of life, development, and quality and accessibility of health care. Improvements in science, technology and better access to health care have contributed to a major decrease in the infant mortality rate in Argentina. Since the 1980s, infant deaths have been classified based on the opportunities for reducibility yielded by scientific knowledge and available technologies, in order to obtain a basis for the monitoring and implementation of health policies. The last review of this classification was in 2011. In 2012, a total of 5,541 neonatal deaths (less than 28 days of life) were registered and, under this new classification, over 61% were reducible mainly by the improvement of perinatal health care and adequate and timely treatment of the at-risk newborn. In 2012, a total of 2,686 post-neonatal deaths (from 28 days of life to a year) were registered and, under this new classification, over 66.8% were reducible by improving prevention strategies and providing adequate and timely treatment. This new analysis demonstrates the need to improve the opportunity, accessibility and quality of perinatal care starting at pregnancy, guaranteeing quality care at delivery and reinforcing prevention and timely treatment of common diseases in childhood over the first year of life.

  12. [Infant Mortality in Argentina: reducibility criteria, 3rd review].

    PubMed

    Finkelstein, Juliana Zoe; Duhau, Mariana; Abeyá Gilardon, Enrique; Ferrario, Claudia; Speranza, Ana; Asciutto, Carolina; Marconi, Élida; Guevel, Carlos; Fernández, María de las Mercedes; Martínez, María Laura; Santoro, Adrián; Loiacono, Karina; Lomuto, Celia

    2015-08-01

    The infant mortality rate is an indicator of quality of life, development, and quality and accessibility of health care. Improvements in science, technology and better access to health care have contributed to a major decrease in the infant mortality rate in Argentina. Since the 1980s, infant deaths have been classified based on the opportunities for reducibility yielded by scientific knowledge and available technologies, in order to obtain a basis for the monitoring and implementation of health policies. The last review of this classification was in 2011. In 2012, a total of 5,541 neonatal deaths (less than 28 days of life) were registered and, under this new classification, over 61% were reducible mainly by the improvement of perinatal health care and adequate and timely treatment of the at-risk newborn. In 2012, a total of 2,686 post-neonatal deaths (from 28 days of life to a year) were registered and, under this new classification, over 66.8% were reducible by improving prevention strategies and providing adequate and timely treatment. This new analysis demonstrates the need to improve the opportunity, accessibility and quality of perinatal care starting at pregnancy, guaranteeing quality care at delivery and reinforcing prevention and timely treatment of common diseases in childhood over the first year of life. PMID:26172012

  13. Fluctuations in Student Understanding of Newton's 3rd Law

    NASA Astrophysics Data System (ADS)

    Clark, Jessica W.; Sayre, Eleanor C.; Franklin, Scott V.

    2010-10-01

    We present data from a between-student study on student response to questions on Newton's Third Law given throughout the academic year. The study, conducted at Rochester Institute of Technology, involved students from the first and third of a three-quarter sequence. Construction of a response curve reveals subtle dynamics in student learning not captured by simple pre/post testing. We find a a significant positive effect from direct instruction, peaking at the end of instruction on forces, that diminishes by the end of the quarter. Two quarters later, in physics III, a significant dip in correct response occurs when instruction changes from the vector quantities of electric forces and fields to the scalar quantity of electric potential. Student response rebounds to its initial values, however, once instruction returns to the vector-based topics involving magnetic fields.

  14. [3rd Hungarian Breast Cancer Consensus Conference - Radiotherapy Guidelines].

    PubMed

    Polgár, Csaba; Kahán, Zsuzsanna; Csejtei, András; Gábor, Gabriella; Landherr, László; Mangel, László; Mayer, Árpád; Fodor, János

    2016-09-01

    The radiotherapy expert panel revised and updated the radiotherapy (RT) guidelines accepted in 2009 at the 2nd Hungarian Breast Cancer Consensus Conference based on new scientific evidence. Radiotherapy of the conserved breast is indicated in ductal carcinoma in situ (St. 0), as RT decreases the risk of local recurrence by 60%. In early stage (St. I-II) invasive breast cancer RT remains a standard treatment following breast conserving surgery. However, in elderly (≥70 years) patients with stage I, hormone receptor positive tumour hormonal therapy without RT can be considered. Hypofractionated (15×2.67 Gy) whole breast irradiation and for selected cases accelerated partial breast irradiation are validated treatment alternatives of conventional (25×2 Gy) whole breast irradiation. Following mastectomy RT significantly decreases the risk of locoregional recurrence and improves overall survival of patients having 1 to 3 (pN1a) or ≥4 (pN2a, pN3a) positive axillary lymph nodes. In selected cases of patients with 1 to 2 positive sentinel lymph nodes axillary dissection can be omitted and substituted with axillary RT. After neoadjuvant chemotherapy (NAC) followed by breast conserving surgery whole breast irradiation is mandatory, while after NAC followed by mastectomy locoregional RT should be given in cases of initial stage III-IV and ypN1 axillary status. PMID:27579722

  15. Explanatory Supplement to the Astronomical Almanac (3rd Edition)

    NASA Astrophysics Data System (ADS)

    Urban, Sean E.; Seidelmann, P. K.

    2014-01-01

    Publications and software from the the Astronomical Applications Department of the US Naval Observatory (USNO) are used throughout the world, not only in the Department of Defense for safe navigation, but by many people including other navigators, astronomers, aerospace engineers, and geodesists. Products such as The Nautical Almanac, The Astronomical Almanac, and the Multiyear Interactive Computer Almanac (MICA) are regarded as international standards. To maintain credibility, it is imperative that the methodologies employed and the data used are well documented. "The Explanatory Supplement to the Astronomical Almanac" (hereafter, "The ES") is a major source of such documentation. It is a comprehensive reference book on positional astronomy, covering the theories and algorithms used to produce The Astronomical Almanac, an annual publication produced jointly by the Nautical Almanac Office of USNO and Her Majesty's Nautical Almanac Office (HMNAO). The first edition of The ES appeared in 1961, and the second followed in 1992. Several major changes have taken place in fundamental astronomy since the second edition was published. Advances in radio observations allowed the celestial reference frame to be tied to extragalactic radio sources, thus the International Celestial Reference System replaced the FK5 system. The success of ESA's Hipparcos satellite dramatically altered observational astrometry. Improvements in Earth orientation observations lead to new precession and nutation theories. Additionally, a new positional paradigm, no longer tied to the ecliptic and equinox, was accepted. Largely because of these changes, staff at USNO and HMNAO decided the time was right for the next edition of The ES. The third edition is now available; it is a complete revision of the 1992 book. Along with subjects covered in the previous two editions, the book also contains descriptions of the major advancements in positional astronomy over the last 20 years, some of which are

  16. Docking and scoring protein complexes: CAPRI 3rd Edition.

    PubMed

    Lensink, Marc F; Méndez, Raúl; Wodak, Shoshana J

    2007-12-01

    The performance of methods for predicting protein-protein interactions at the atomic scale is assessed by evaluating blind predictions performed during 2005-2007 as part of Rounds 6-12 of the community-wide experiment on Critical Assessment of PRedicted Interactions (CAPRI). These Rounds also included a new scoring experiment, where a larger set of models contributed by the predictors was made available to groups developing scoring functions. These groups scored the uploaded set and submitted their own best models for assessment. The structures of nine protein complexes including one homodimer were used as targets. These targets represent biologically relevant interactions involved in gene expression, signal transduction, RNA, or protein processing and membrane maintenance. For all the targets except one, predictions started from the experimentally determined structures of the free (unbound) components or from models derived by homology, making it mandatory for docking methods to model the conformational changes that often accompany association. In total, 63 groups and eight automatic servers, a substantial increase from previous years, submitted docking predictions, of which 1994 were evaluated here. Fifteen groups submitted 305 models for five targets in the scoring experiment. Assessment of the predictions reveals that 31 different groups produced models of acceptable and medium accuracy-but only one high accuracy submission-for all the targets, except the homodimer. In the latter, none of the docking procedures reproduced the large conformational adjustment required for correct assembly, underscoring yet again that handling protein flexibility remains a major challenge. In the scoring experiment, a large fraction of the groups attained the set goal of singling out the correct association modes from incorrect solutions in the limited ensembles of contributed models. But in general they seemed unable to identify the best models, indicating that current scoring

  17. 3rd International Conference on Turbulent Mixing and Beyond

    NASA Astrophysics Data System (ADS)

    Abarzhi, Snezhana I.; Gauthier, Serge; Keane, Christopher J.; Niemela, Joseph J.

    2013-07-01

    National Academies of Sciences and Engineering, and including researchers at experienced and early stages of their careers from leading scientific institutions in academia, national laboratories, corporations and industry, from developed and developing countries across five continents. The success of TMB-2011 consisted from the successful work of the conference participants, who were responsible professionals caring for the quality of their research and sharing their scientific vision. The level of presentations was high, and 205 presentations included about 50 invited lectures, nearly 70 oral talks (3500 min of talks in total), some 90 posters and one round table. The special course on 'Turbulence and Waves' was organized at TMB-2011 with the support of the US Office of Naval Research Global, and included nearly 40 lectures and talks (960 minutes of talks in total). TMB-2011 covered 16 different topics, maintaining the scope and the interdisciplinary character of the meeting and at the same time keeping the focus on a fundamental scientific problem of non-equilibrium processes and on the conference objectives. The topics included: • Canonical turbulent and turbulent mixing: invariant, scaling, spectral properties, scalar transports, convection. • Wall-bounded flows: structure and fundamentals, non-canonical turbulent boundary layers, including unsteady and transitional flows, supersonic and hypersonic flows, shock-boundary layer interactions. • Non-equilibrium processes: unsteady, multiphase and shock-driven turbulent flows, anisotropic non-local dynamics, connection of continuous description at macro-scales to kinetic processes at atomistic scales. • Interfacial dynamics: the instabilities of Rayleigh-Taylor, Kelvin-Helmholtz, Richtmyer-Meshkov, Landau-Darrieus, Saffmann-Taylor. • High energy density physics: inertial confinement and heavy-ion fusion, Z-pinches, light-material and laser-plasma interaction, non-equilibrium heat transfer. • Material science

  18. PREFACE: 3rd International Workshop on Infrared Plasma Spectroscopy

    NASA Astrophysics Data System (ADS)

    Davies, P. B.; Röpcke, Jürgen; Hempel, Frank

    2009-07-01

    This volume containsd a selection of papers from the third Infrared Plasma Spectroscopy (IPS) Workshop held in Greifswald, Germany in July 2008. Although not all the contributions have been written up in time for the deadline for this volume, nevertheless the 12 contributions presented here give a fair representation of the conference topics. The conference comprised four different types of contribution. Firstly, four invited lectures focussed on the prime areas of interest. Secondly, eight shorter contributed talks, grouped as closely as possible with the appropriate invited lecture. These contributed talks covered topics in both pure and applied infrared plasma spectroscopy. A feature of the two previous IPS conferences has been a contribution from commercial organisations namely those involved in manufacturing devices, detectors and spectrometers. This group of participants formed the third part of the conference programme and gave five oral presentations covering topics like QCL and detector/detection developments and novel spectrometer designs. The fourth contributing group comprised 27 poster presentations. It should be mentioned that some of the latter were poster versions of contributed talks. The conference was remarkable for the wide spread of topics covered in a relatively small meeting, consisting of 44 participants. The participants were made up of 34 scientists from within Europe and 4 from the rest of the world. It is interesting to reflect on changes that have occurred since the previous meeting just a year earlier. Two clear developments which have occurred are the emergence of Quantum Cascade Lasers (QCL) and their use in Cavity Ring Down (CRD) spectroscopy. A major shift from cw lead salt diode lasers to cw and pulsed QCL in both pure and applied projects now seems to be well under way. The topics covered in the earlier conferences focussed more on applying infrared spectroscopy to plasma monitoring and control. When choosing the topics to cover

  19. 3rd hand smoking; heterogeneous oxidation of nicotine and secondary aerosol formation in the indoor environment

    NASA Astrophysics Data System (ADS)

    Petrick, Lauren; Dubowski, Yael

    2010-05-01

    Tobacco smoking is well known as a significant source of primary indoor air pollutants. However, only recently has it been recognized that the impact of Tobacco smoking may continue even after the cigarette has been extinguished (i.e., third hand smoke) due to the effect of indoor surfaces. These surfaces may affect the fate of tobacco smoke in the form of secondary reactions and pollutants, including secondary organic aerosol (SOA) formation. Fourier Transform Infrared spectrometry with Attenuated Total Reflection (FTIR-ATR) in tandem with a Scanning Mobility Particle Sizing (SMPS) system was used to monitor the ozonation of cellulose sorbed nicotine and resulting SOA formation. SOA formation began at onset of ozone introduction ([O3] = 60 ± 5 ppb) with a size distribution of dp ≤ 25 nm, and was determined to be a result of heterogeneous reaction (opposed to homogeneous). SOA yield from reacted surface nicotine was on the order of 10 %. Simultaneous to SOA monitoring, FTIR-ATR spectra showed surface changes in the nicotine film as the reaction progressed, revealing a pseudo first-order surface reaction rate of 0.0026 ± 0.0008 min-1. Identified surface oxidation products included: cotinine, myosmine, methylnicotinamide and nicotyrine. Surface reaction rate was found to be partially inhibited at high relative humidity. Given the toxicity of some of the identified products (e.g., cotinine has shown potential mutagenicity and teratogenicity) and that small particles may contribute to adverse health effects, the present study indicates that exposure to 3rd hand smoke ozonation products may pose additional health risks.

  20. 16. 3RD FLOOR, J.M. LEHMANN CO. FIVEROLL TOILET SOAP MILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. 3RD FLOOR, J.M. LEHMANN CO. FIVE-ROLL TOILET SOAP MILL INSTALLED 1950, TO WEST; BUCKET CONVEYOR AT RIGHT MOVED WASTE FROM 2ND FLOOR SOAP PRESSES TO 5TH FLOOR RE-MANUFACTURE - Colgate & Company Jersey City Plant, Building No. B-14, 54-58 Grand Street, Jersey City, Hudson County, NJ

  1. 75 FR 34450 - Filing Dates for the Indiana Special Election in the 3rd Congressional District

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... From the Federal Register Online via the Government Publishing Office FEDERAL ELECTION COMMISSION Filing Dates for the Indiana Special Election in the 3rd Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: Indiana has scheduled a...

  2. Colorectal cancer in inflammatory bowel disease: results of the 3rd ECCO pathogenesis scientific workshop (I).

    PubMed

    Sebastian, Shaji; Hernández, Vincent; Myrelid, Pär; Kariv, Revital; Tsianos, Epameinondas; Toruner, Murat; Marti-Gallostra, Marc; Spinelli, Antonino; van der Meulen-de Jong, Andrea E; Yuksel, Elif Sarıtas; Gasche, Christoph; Ardizzone, Sandro; Danese, Silvio

    2014-01-01

    Epidemiological studies demonstrate an increased risk of colorectal cancer in patients with inflammatory bowel disease (IBD). A detailed literature review was conducted on epidemiology, risk factors, pathophysiology, chemoprevention and outcomes of colorectal cancer (CRC) in IBD as part of the 3rd ECCO scientific pathogenesis workshop.

  3. PreK-3rd: What Is the Price Tag? Policy to Action Brief. No. 2

    ERIC Educational Resources Information Center

    Shore, Rima

    2009-01-01

    In an era of intense fiscal pressures, educators are focusing on those investments most likely to lift student achievement. They are also trying to make more strategic use of existing resources. To achieve these goals, a growing number of policymakers are considering integrated PreK-3rd approaches. Increasingly, they are recognizing that the first…

  4. Evaluation of the "Respect Not Risk" Firearm Safety Lesson for 3rd-Graders

    ERIC Educational Resources Information Center

    Liller, Karen D.; Perrin, Karen; Nearns, Jodi; Pesce, Karen; Crane, Nancy B.; Gonzalez, Robin R.

    2003-01-01

    The purpose of this study was to evaluate the MORE HEALTH "Respect Not Risk" Firearm Safety Lesson for 3rd-graders in Pinellas County, Florida. Six schools representative of various socioeconomic levels were selected as the test sites. Qualitative and quantitative data were collected. A total of 433 matched pretests/posttests were used to…

  5. Using Food as a Tool to Teach Science to 3rd Grade Students in Appalachian Ohio

    ERIC Educational Resources Information Center

    Duffrin, Melani W.; Hovland, Jana; Carraway-Stage, Virginia; McLeod, Sara; Duffrin, Christopher; Phillips, Sharon; Rivera, David; Saum, Diana; Johanson, George; Graham, Annette; Lee, Tammy; Bosse, Michael; Berryman, Darlene

    2010-01-01

    The Food, Math, and Science Teaching Enhancement Resource (FoodMASTER) Initiative is a compilation of programs aimed at using food as a tool to teach mathematics and science. In 2007 to 2008, a foods curriculum developed by professionals in nutrition and education was implemented in 10 3rd-grade classrooms in Appalachian Ohio; teachers in these…

  6. The Effect of Book Blogging on the Motivation of 3rd-Grade Students

    ERIC Educational Resources Information Center

    Swanson, Kristen N.; Legutko, Robert S.

    2008-01-01

    A Web 2.0 technology was implemented during reading instruction in one 3rd-grade classroom in suburban southeastern Pennsylvania. Trained preservice teachers provided feedback to students via the World Wide Web to enhance their performance and social connections. Motivation scores were measured before and after the intervention was implemented. A…

  7. PREFACE: 3rd International Conference on Geological, Geographical, Aerospace and Earth Science 2015 (AeroEarth 2015)

    NASA Astrophysics Data System (ADS)

    Gaol, F. L.

    2016-02-01

    The 3rd International Conferences on Geological, Geographical, Aerospaces and Earth Sciences 2015 (AeroEarth 2015), was held at The DoubleTree Hilton, Jakarta, Indonesia during 26 - 27 September 2015. The 1st AeoroEarth was held succefully in Jakarta in 2013. The success continued to The 2nd AeroEarth 2014 that was held in Kuta Bali, Indonesia. The publications were published by EES IOP in http://iopscience.iop.org/1755-1315/19/1 and http://iopscience.iop.org/1755-1315/23/1 respectively. The AeroEarth 2015 conference aims to bring together researchers, engineers and scientists from around the world. Through research and development, Earth's scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. The theme of AeroEarth 2015 is ''Earth and Aerospace Sciences : Challenges and Opportunities'' Earth provides resources and the exact conditions to make life possible. However, with the advent of technology and industrialization, the Earth's resources are being pushed to the brink of depletion. Non-sustainable industrial practices are not only endangering the supply of the Earth's natural resources, but are also putting burden on life itself by bringing about pollution and climate change. A major role of earth science scholars is to examine the delicate balance between the Earth's resources and the growing demands of industrialization. Through research and development, earth scientists have the power to preserve the planet's different resource domains by providing expert opinion and information about the forces which make life possible on Earth. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program as well as the invited and plenary speakers. This year, we received 78 papers and after rigorous review, 18 papers were accepted. The participants

  8. Foundational Skills to Support Reading for Understanding in Kindergarten through 3rd Grade. Educator's Practice Guide. NCEE 2016-4008

    ERIC Educational Resources Information Center

    Foorman, Barbara; Beyler, Nicholas; Borradaile, Kelley; Coyne, Michael; Denton, Carolyn A.; Dimino, Joseph; Furgeson, Joshua; Hayes, Lynda; Henke, Juliette; Justice, Laura; Keating, Betsy; Lewis, Warnick; Sattar, Samina; Streke, Andrei; Wagner, Richard; Wissel, Sarah

    2016-01-01

    The goal of this practice guide is to offer educators specific, evidence-based recommendations for teaching foundational reading skills to students in kindergarten through 3rd grade. This guide is a companion to the existing practice guide, "Improving Reading Comprehension in Kindergarten Through 3rd Grade", and as a set, these guides…

  9. THE 3rd SCHIZOPHRENIA INTERNATIONAL RESEARCH SOCIETY CONFERENCE, 14-18 APRIL 2012, FLORENCE, ITALY: SUMMARIES OF ORAL SESSIONS

    PubMed Central

    Abbs, Brandon; Achalia, Rashmin M; Adelufosi, Adegoke O; Aktener, Ahmet Yiğit; Beveridge, Natalie J; Bhakta, Savita G; Blackman, Rachael K; Bora, Emre; Byun, MS; Cabanis, Maurice; Carrion, Ricardo; Castellani, Christina A; Chow, Tze Jen; Dmitrzak-Weglarz, M; Gayer-Anderson, Charlotte; Gomes, Felipe V; Haut, Kristen; Hori, Hiroaki; Kantrowitz, Joshua T; Kishimoto, Taishiro; Lee, Frankie HF; Lin, Ashleigh; Palaniyappan, Lena; Quan, Meina; Rubio, Maria D; Ruiz de Azúa, Sonia; Sahoo, Saddichha; Strauss, Gregory P; Szczepankiewicz, Aleksandra; Thompson, Andrew D; Trotta, Antonella; Tully, Laura M; Uchida, Hiroyuki; Velthorst, Eva; Young, Jared W; O’Shea, Anne; DeLisi, Lynn E.

    2013-01-01

    The 3rd Schizophrenia International Research Society Conference was held in Florence, Italy, April 14-18, 2012.and this year had as its emphasis, “The Globalization of Research”. Student travel awardees served as rapporteurs for each oral session and focused their summaries on the most significant findings that emerged and the discussions that followed. The following report is a composite of these summaries. We hope that it will provide an overview for those who were present, but could not participate in all sessions, and those who did not have the opportunity to attend, but who would be interested in an update on current investigations ongoing in the field of schizophrenia research. PMID:22910407

  10. SESAME - A 3rd Generation Synchrotron Light Source for the Middle East

    SciTech Connect

    Ulkue, Dincer; Rahighi, Javad; Winick, Herman

    2007-01-19

    SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK, and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference {approx}133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member

  11. Conference report: the 3rd Global CRO Council for Bioanalysis at the International Reid Bioanalytical Forum.

    PubMed

    Breda, Massimo; Garofolo, Fabio; Caturla, Maria Cruz; Couerbe, Philippe; Maltas, John; White, Peter; Struwe, Petra; Sangster, Timothy; Riches, Suzanne; Hillier, Jim; Garofolo, Wei; Zimmerman, Thomas; Pawula, Maria; Collins, Eileen; Schoutsen, Dick; Wieling, Jaap; Green, Rachel; Houghton, Richard; Jeanbaptiste, Bernard; Claassen, Quinton; Harter, Tammy; Seymour, Mark

    2011-12-01

    The 3rd Global CRO Council Closed Forum was held on the 3rd and 4th July 2011 in Guildford, United Kingdom, in conjunction with the 19th International Reid Bioanalytical Forum. In attendance were 21 senior-level representatives from 19 CROs on behalf of nine European countries and, for many of the attendees, this occasion was the first time that they had participated in a GCC meeting. Therefore, this closed forum was an opportunity to increase awareness of the aim of the GCC and how it works, share information about bioanalytical regulations and audit findings from different agencies, their policies and procedures and also to discuss some topics of interest and aim to develop ideas and provide recommendations for bioanalytical practices at future GCC meetings in Europe.

  12. Higher order modes of a 3rd harmonic cavity with an increased end-cup iris

    SciTech Connect

    T. Khabibouline; N. Solyak; R. Wanzenberg

    2003-05-19

    The cavity design for a 3rd harmonic cavity for the TTF 2 photoinjector has been revised to increase the coupling between the main coupler and the cavity cells. The iris radius of the end cup of the cavity has been increased to accomplish a better coupling. The basic rf-parameters and the higher order modes of the modified design are summarized in this report.

  13. Insights from the 3rd World Congress on Integrated Computational Materials Engineering

    NASA Astrophysics Data System (ADS)

    Howe, D.; Goodlet, B.; Weaver, J.; Spanos, G.

    2016-05-01

    The 3rd World Congress on Integrated Computational Materials Engineering (ICME) was a forum for presenting the "state-of-the-art" in the ICME discipline, as well as for charting a path for future community efforts. The event concluded with in an interactive panel-led discussion that addressed such topics as integrating efforts between experimental and computational scientists, uncertainty quantification, and identifying the greatest challenges for future workforce preparation. This article is a summary of this discussion and the thoughts presented.

  14. 13. Photocopy of 1920 drawing titled: BUILDING 78, 3RD FLOOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photocopy of 1920 drawing titled: BUILDING 78, 3RD FLOOR BALCONY AND FIRE ESCAPES, including plans for skylight and North Elevation. HABS photograph is an 8x10' contact print made from a high contrast negative of an enlargement made from microfiche. Original is in the collection of Department of Public Works, Puget Sound Naval Shipyard, Bremerton, WA. - Puget Sound Naval Shipyard, Administration Building, Farragut Avenue, Bremerton, Kitsap County, WA

  15. Finance issue brief: continuity of care: year end report-2003.

    PubMed

    MacEachern, Lillian

    2003-12-31

    When a health care provider leaves or is terminated by a managed care plan, how long can patients continue to receive covered treatment from that provider for a life-threatening condition, pregnancy, disability or other circumstance that requires continuous medical care? Lawmakers in 36 states have answered that question. PMID:14964235

  16. Finance issue brief: continuity of care: year end report-2002.

    PubMed

    Morgan, Rachel; MacEachern, Lillian

    2002-12-31

    When a health care provider leaves or is terminated by a managed care plan, how long can patients continue to receive covered treatment from that provider for a life-threatening condition, pregnancy, disability or other circumstance that requires continuous medical care? Lawmakers in 36 states have answered that question. PMID:12886925

  17. The Goodrich 3rd generation DB-110 system: successful flight test on the F-16 aircraft

    NASA Astrophysics Data System (ADS)

    Lange, Davis; Iyengar, Mrinal; Maver, Larry; Dyer, Gavin; Francis, John

    2007-04-01

    The 3rd Generation Goodrich DB-110 system provides users with a three (3) field-of-view high performance Airborne Reconnaissance capability that incorporates a dual-band day and nighttime imaging sensor, a real time recording and a real time data transmission capability to support long range, medium range, and short range standoff and over-flight mission scenarios, all within a single pod. Goodrich developed their 3rd Generation Airborne Reconnaissance Pod for operation on a range of aircraft types including F-16, F-15, F-18, Euro-fighter and older aircraft such as the F-4, F-111, Mirage and Tornado. This system upgrades the existing, operationally proven, 2nd generation DB-110 design with enhancements in sensor resolution, flight envelope and other performance improvements. Goodrich recently flight tested their 3rd Generation Reconnaissance System on a Block 52 F-16 aircraft with first flight success and excellent results. This paper presents key highlights of the system and presents imaging results from flight test.

  18. Using Photographs to Probe Students' Understanding of Physical Concepts: The Case of Newton's 3rd Law

    NASA Astrophysics Data System (ADS)

    Eshach, Haim

    2010-08-01

    The starting point of the present research is the following question: since we live in an age that makes increasing use of visual representations of all sorts, is not the visual representation a learner constructs a window into his/her understanding of what is or is not being learned? Following this direction of inquiry, the present preliminary study introduces and evaluates a novel technique for pinpointing learners’ misconceptions, namely, one that has learners create and interpret their own photographs (CIP). 27 high-school students and 26 pre-service teacher trainees were asked to assume the role of textbook designers and create a display—photograph plus attached verbal explanation—which, in their opinion, best depicted Newton’s 3rd law. Subsequent analysis of the participants’ photographs yielded the following six misconception categories: 3rd law not depicted; 3rd law depicts a sequence of events; tendency to introduce irrelevant entities in explanations; the word ‘reaction’ used colloquially; tendency to restrict the application of the third law to dynamic situations; and informal explanations in which the word “force” is absent. The findings indicate that, indeed, the CIP method can be effectively employed to elicit, detect, and investigate learners’ misconceptions. The CIP method joins the growing efforts to utilize the yet relatively untapped potential of visual tools for science education purposes.

  19. PREFACE: 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"

    NASA Astrophysics Data System (ADS)

    Yamada, Taiichi; Kanada-En'yo, Yoshiko

    2014-12-01

    The 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3) was held at KGU Kannai Media Center, Kanto Gakuin University, Yokohama, Japan, from May 26 to 30, 2014. Yokohama is the second largest city in Japan, about 25 km southeast of Tokyo. The first workshop of the series was held in Strasbourg, France, in 2008 and the second one was in Brussels, Belgium, in 2010. The purpose of SOTANCP3 was to discuss the present status and future perspectives of the nuclear cluster physics. The following nine topics were selected in order to cover most of the scientific programme and highlight an area where new ideas have emerged over recent years: (1) Cluster structures and many-body correlations in stable and unstable nuclei (2) Clustering aspects of nuclear reactions and resonances (3) Alpha condensates and analogy with condensed matter approaches (4) Role of tensor force in cluster physics and ab initio approaches (5) Clustering in hypernuclei (6) Nuclear fission, superheavy nuclei, and cluster decay (7) Cluster physics and nuclear astrophysics (8) Clustering in nuclear matter and neutron stars (9) Clustering in hadron and atomic physics There were 122 participants, including 53 from 17 foreign countries. In addition to invited talks, we had many talks selected from contributed papers. There were plenary, parallel, and poster sessions. Poster contributions were also presented as four-minute talks in parallel sessions. This proceedings contains the papers presented in invited and selected talks together with those presented in poster sessions. We would like to express our gratitude to the members of the International Advisory Committee and those of the Organizing Committee for their efforts which made this workshop successful. In particular we would like to present our great thanks to Drs. Y. Funaki, W. Horiuchi, N. Itagaki, M. Kimura, T. Myo, and T. Yoshida. We would like also to thank the following organizations for their sponsors: RCNP

  20. Interim Performance Objectives. Progress Report, 3rd Quarter Fiscal Year 1999.

    ERIC Educational Resources Information Center

    Office of Student Financial Assistance (ED), Washington, DC.

    This document contains a progress report on three categories of interim performance objectives outlined by the Office of Student Financial Assistance (OSFA) in winter 1999. These objectives were to: (1) improve customer service; (2) reduce the overall cost of delivering student aid; and (3) transform the OSFA into a performance-based organization.…

  1. Preface to Special Topic: Invited Papers of the 3rd International Conference on Ultrafast Structural Dynamics

    PubMed Central

    Johnson, S. L.

    2016-01-01

    The ability to visualize the real-time dynamics of atomic, magnetic, and electronic structure is widely recognized in many fields as a key element underpinning many important processes in chemistry, materials science, and biology. The need for an improved understanding of such processes becomes acute as energy conversion processes on fast time scales become increasingly relevant to problems in science and technology. This special issue, containing invited papers from participants at the 3rd International Conference on Ultrafast Structural Dynamics held June 10–12, 2015 in Zurich, Switzerland, discusses several recent developments in this area. PMID:27191008

  2. NURSING EMERGING. ANA Nursing: Scope and Standards of Practice, (2015) 3rd Edition.

    PubMed

    Mariano, Carla

    2016-04-01

    AHNA Past-President Carla Mariano recently had the privilege of serving on the American Nurses Association's (ANA) Nursing Scope and Standards Revision Workgroup. Representing the specialty practice of holistic nursing, Carla's presence within this workgroup contributed greatly to the inclusion of holistic principles and values throughout the new 2015 Nursing: Scope and Standards of Practice, 3rd edition, the foundational document that informs and guides professional nursing practice within the United States. This is a significant step forward for holistic nursing and an indicator of our growing influence as specialty practice. PMID:27305802

  3. Preface to Special Topic: Invited Papers of the 3rd International Conference on Ultrafast Structural Dynamics.

    PubMed

    Johnson, S L

    2016-03-01

    The ability to visualize the real-time dynamics of atomic, magnetic, and electronic structure is widely recognized in many fields as a key element underpinning many important processes in chemistry, materials science, and biology. The need for an improved understanding of such processes becomes acute as energy conversion processes on fast time scales become increasingly relevant to problems in science and technology. This special issue, containing invited papers from participants at the 3rd International Conference on Ultrafast Structural Dynamics held June 10-12, 2015 in Zurich, Switzerland, discusses several recent developments in this area. PMID:27191008

  4. Overview of the 3rd isirv-Antiviral Group Conference – advances in clinical management

    PubMed Central

    Hurt, Aeron C; Hui, David S; Hay, Alan; Hayden, Frederick G

    2015-01-01

    This review highlights the main points which emerged from the presentations and discussions at the 3rd isirv-Antiviral Group Conference - advances in clinical management. The conference covered emerging and potentially pandemic influenza viruses and discussed novel/pre-licensure therapeutics and currently approved antivirals and vaccines for the control of influenza. Current data on approved and novel treatments for non-influenza respiratory viruses such as MERS-CoV, respiratory syncytial virus (RSV) and rhinoviruses and the challenges of treating immunocompromised patients with respiratory infections was highlighted. PMID:25399715

  5. Education and Development: Thirty Years of Continuity and Change

    ERIC Educational Resources Information Center

    McGrath, Simon

    2010-01-01

    At the end of the 30th volume of IJED and in the year that the journal published its 1000th paper, it is appropriate to look back at the journal's development. In doing so, this article will discuss a series of important issues regarding the future of the field of international education and development and how it engages with development studies.…

  6. 100 Years of Commitment to Children: Change and Continuity.

    ERIC Educational Resources Information Center

    Shore, Rima

    The Foundation for Child Development (FCD) is the oldest philanthropy in the nation focused on improving the life prospects of children. This booklet, produced for FCD's centennial, describes the organization's origins and changes during the past 100 years. The booklet's sections, which include photographs, quotes, and a timeline, are: (1) "The…

  7. 33 Years of Continuous Solar Radio Flux Observations

    NASA Astrophysics Data System (ADS)

    Monstein, Christian

    2015-10-01

    In 1982, after development and testing of several analog receiver concepts, I started continuous solar radio flux observations at 230 MHz. My instruments for the observations were based on cheap commercial components out of consumer TV electronics. The main components included a TV-tuner (at that time analog), intermediate frequency (IF) amplifier and video-detector taken from used TV sets. The 5.5 MHz wide video signal was fed into an integrating circuit, in fact a low pass filter, followed by dc-offset circuit and dc-amplifier built with four ua741 and CA3140 operational amplifier integrated circuits. At that time the signal was recorded with a Heathkit stripchart recorder and ink pen; an example is shown in figure 1.

  8. Extreme and Local 3rd Harmonic Response of Niobium (Nb) Superconductor

    NASA Astrophysics Data System (ADS)

    Oripov, Bakhrom; Tai, Tamin; Anlage, Steven

    Superconducting Radio Frequency (SRF) cavities are being widely used in new generation particle accelerators. These SRF cavities are based on bulk Nb. Based on the needs of the SRF community to identify defects on Nb surfaces, a novel near-field magnetic microwave microscope was successfully built using a magnetic writer from a conventional magnetic recording hard-disk drive1. This magnetic writer can create an RF magnetic field, localized and strong enough to drive Nb into the vortex state. This probe enables us to locate defects through scanning and mapping of the local electrodynamic response in the multi-GHz frequency range. Recent measurements have shown that 3rd harmonic nonlinear response is far more sensitive to variations in input power and temperature then linear response, thus we mainly study the 3rd harmonic response. Moreover, the superconductor is usually the only source for nonlinear response in our setup, thus there is less chance of having noise or background signal. Understanding the mechanism responsible for this non-linear response is important for improving the performance of SRF cavities. Besides Nb we also study various other superconductors such as MgB2 and the cuprate Bi-Sr-Ca-Cu-O (BSCCO) for potential applications in SRF cavities. This work is funded by US Department of Energy through Grant # DE-SC0012036T and CNAM.

  9. Treatment of 3rd molar-induced periodontal defects with guided tissue regeneration.

    PubMed

    Oxford, G E; Quintero, G; Stuller, C B; Gher, M E

    1997-07-01

    Recent reports provide evidence of increased attachment levels when using guided tissue regeneration (GTR) techniques for the treatment of periodontal defects. Periodontal defects frequently occur at the distal aspect of mandibular 2nd molars which are next to mesioangular impacted 3rd molars that have oral communication. The purpose of this study was to determine whether the use of GTR can enhance probing attachment levels (PALs) following extraction of mesioangular impacted third molars. 12 patients with bilateral soft tissue impacted mandibular 3rd molars entered this split mouth study. After extractions, the previously exposed distal root surface of the 2nd molars were debrided. The defects on the randomly selected experimental sites were covered with expanded polytetraflouro-ethylene (e-PTFE) membrane and the tissue was replaced to cover the membrane. Membranes were removed after 6 weeks. Control sites were treated identically except no membrane was placed. GI, P1I, PD, PAL and BOP records were obtained at 0, 3 and 6 months. The use of barrier material did not provide statistically-significant differences in PAL when comparing experimental versus control sites. Nevertheless, PAL gain was consistently greater at 3 and 6 months when GTR techniques were used in sites with deep impactions. PMID:9226386

  10. PREFACE: 3rd International Workshop on Materials Analysis and Processing in Magnetic Fields (MAP3)

    NASA Astrophysics Data System (ADS)

    Sakka, Yoshio; Hirota, Noriyuki; Horii, Shigeru; Ando, Tsutomu

    2009-07-01

    The 3rd International Workshop on Materials Analysis and Processing in Materials Fields (MAP3) was held on 14-16 May 2008 at the University of Tokyo, Japan. The first was held in March 2004 at the National High Magnetic Field Laboratory in Tallahassee, USA. Two years later the second took place in Grenoble, France. MAP3 was held at The University of Tokyo International Symposium, and jointly with MANA Workshop on Materials Processing by External Stimulation, and JSPS CORE Program of Construction of the World Center on Electromagnetic Processing of Materials. At the end of MAP3 it was decided that the next MAP4 will be held in Atlanta, USA in 2010. Processing in magnetic fields is a rapidly expanding research area with a wide range of promising applications in materials science. MAP3 focused on the magnetic field interactions involved in the study and processing of materials in all disciplines ranging from physics to chemistry and biology: Magnetic field effects on chemical, physical, and biological phenomena Magnetic field effects on electrochemical phenomena Magnetic field effects on thermodynamic phenomena Magnetic field effects on hydrodynamic phenomena Magnetic field effects on crystal growth Magnetic processing of materials Diamagnetic levitation Magneto-Archimedes effect Spin chemistry Application of magnetic fields to analytical chemistry Magnetic orientation Control of structure by magnetic fields Magnetic separation and purification Magnetic field-induced phase transitions Materials properties in high magnetic fields Development of NMR and MRI Medical application of magnetic fields Novel magnetic phenomena Physical property measurement by Magnetic fields High magnetic field generation> MAP3 consisted of 84 presentations including 16 invited talks. This volume of Journal of Physics: Conference Series contains the proceeding of MAP3 with 34 papers that provide a scientific record of the topics covered by the conference with the special topics (13 papers) in

  11. 78 FR 58291 - TRICARE; Fiscal Year 2014 Continued Health Care Benefit Program Premium Update

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... of the Secretary TRICARE; Fiscal Year 2014 Continued Health Care Benefit Program Premium Update AGENCY: Office of the Secretary, DoD. ACTION: Notice of Updated Continued Health Care Benefit Program Premiums for Fiscal Year 2014. SUMMARY: This notice provides the updated Continued Health Care...

  12. Malaria and Fetal Growth Alterations in the 3rd Trimester of Pregnancy: A Longitudinal Ultrasound Study

    PubMed Central

    Schmiegelow, Christentze; Minja, Daniel; Oesterholt, Mayke; Pehrson, Caroline; Suhrs, Hannah Elena; Boström, Stéphanie; Lemnge, Martha; Magistrado, Pamela; Rasch, Vibeke; Nielsen, Birgitte Bruun; Lusingu, John; Theander, Thor G.

    2013-01-01

    Background Pregnancy associated malaria is associated with decreased birth weight, but in-utero evaluation of fetal growth alterations is rarely performed. The objective of this study was to investigate malaria induced changes in fetal growth during the 3rd trimester using trans-abdominal ultrasound. Methods An observational study of 876 pregnant women (398 primi- and secundigravidae and 478 multigravidae) was conducted in Tanzania. Fetal growth was monitored with ultrasound and screening for malaria was performed regularly. Birth weight and fetal weight were converted to z-scores, and fetal growth evaluated as fetal weight gain from the 26th week of pregnancy. Results Malaria infection only affected birth weight and fetal growth among primi- and secundigravid women. Forty-eight of the 398 primi- and secundigravid women had malaria during pregnancy causing a reduction in the newborns z-score of −0.50 (95% CI: −0.86, −0.13, P = 0.008, multiple linear regression). Fifty-eight percent (28/48) of the primi- and secundigravidae had malaria in the first half of pregnancy, but an effect on fetal growth was observed in the 3rd trimester with an OR of 4.89 for the fetal growth rate belonging to the lowest 25% in the population (95%CI: 2.03–11.79, P<0.001, multiple logistic regression). At an individual level, among the primi- and secundigravidae, 27% experienced alterations of fetal growth immediately after exposure but only for a short interval, 27% only late in pregnancy, 16.2% persistently from exposure until the end of pregnancy, and 29.7% had no alterations of fetal growth. Conclusions The effect of malaria infections was observed during the 3rd trimester, despite infections occurring much earlier in pregnancy, and different mechanisms might operate leading to different patterns of growth alterations. This study highlights the need for protection against malaria throughout pregnancy and the recognition that observed changes in fetal growth might be a

  13. Meeting Report: 3rd International Workshop on Insulin & Cancer Heidelberg, Germany, October 30-31, 2010

    PubMed Central

    2010-01-01

    The 3rd International Workshop on Insulin & Cancer was held on October 30-31, 2010 at the German Cancer Research Centre in Heidelberg/Germany. The topics followed-up the discussions of the previous workshops: possible differences in mitogenicity between natural insulin and genetically engineered insulin derivatives (insulin analogues), as shown by laboratory studies and epidemiologic studies alike; molecular studies on the links between metabolic and mitogenic effects of insulin, and of hyperinsulinaemia in particular; epidemiologic evidence of interferences between insulin and other hormones, particularly sex hormones, and obesity-associated cancer; the involvement of inflammatory cytokines produced by fat tissue in obesity-associated cancer; aspects of drug-design (binding drugs to albumin) and, last but not least, detection and investigation of circulating cancer cells. PMID:21176129

  14. Meeting report: 3rd international workshop on insulin & cancer heidelberg, Germany, october 30-31, 2010.

    PubMed

    Chantelau, Ernst; Mayer, Doris

    2010-01-01

    The 3rd International Workshop on Insulin & Cancer was held on October 30-31, 2010 at the German Cancer Research Centre in Heidelberg/Germany. The topics followed-up the discussions of the previous workshops: possible differences in mitogenicity between natural insulin and genetically engineered insulin derivatives (insulin analogues), as shown by laboratory studies and epidemiologic studies alike; molecular studies on the links between metabolic and mitogenic effects of insulin, and of hyperinsulinaemia in particular; epidemiologic evidence of interferences between insulin and other hormones, particularly sex hormones, and obesity-associated cancer; the involvement of inflammatory cytokines produced by fat tissue in obesity-associated cancer; aspects of drug-design (binding drugs to albumin) and, last but not least, detection and investigation of circulating cancer cells.

  15. Passive solar progress: a simplified guide to the 3rd national passive solar conference

    SciTech Connect

    Miller, H.; Howell, Y.; Richards, D.

    1980-10-01

    Some of the concepts and practices that have come to be known as passive solar heating and cooling are introduced, and a current picture of the field is presented. Much of the material presented is derived from papers given at the 3rd National Passive Solar Conference held in San Jose, California in January 1979 and sponsored by the US Department of Energy. Extracts and data from these papers have been integrated in the text with explanatory and descriptive material. In this way, it is attempted to present technical information in an introductory context. Topics include design considerations, passive and hybrid systems and applications, sizing methods and performance prediction, and implementation issues. A glossary is included. (WHK)

  16. Dental health in antique population of Vinkovci - Cibalae in Croatia (3rd-5th century).

    PubMed

    Peko, Dunja; Vodanović, Marin

    2016-08-01

    Roman city Cibalae (Vinkovci) - the birthplace of Roman emperors Valentinian I and Valens was a very well developed urban ares in the late antique what was evidenced by numerous archaeological findings. The aim of this paper is to get insight in dental health of antique population of Cibalae. One hundred individuals with 2041 teeth dated to 3rd - 5th century AD have been analyzed for caries, antemortem tooth loss, periapical diseases and tooth wear. Prevalence of antemortem tooth loss was 4.3% in males, 5.2% in females. Prevalence of caries per tooth was 8.4% in males, 7.0% in females. Compared to other Croatian antique sites, ancient inhabitants of Roman Cibalae had rather good dental health with low caries prevalence and no gender differences. Statistically significant difference was found between males in females in the prevalence of periapical lesions and degree of tooth wear. Periapical lesions were found only in males. PMID:27598951

  17. Food: The Chemistry of Its Components, 3rd Edition (by T. P. Coultate)

    NASA Astrophysics Data System (ADS)

    Carandang, Rachelle; Ziegler, Greg

    1998-02-01

    Food: The Chemistry of Its Components, 3rd edition, by T. P. Coultate, is an excellent textbook in food chemistry for undergraduates. It is a concise version of the very detailed Food Chemistry by Fennema and similar to, but with advantages over, Mechanism and Theory in Food Chemistry by Wong and Principles of Food Chemistry by Deman. The book assumes knowledge of biochemistry and basic principles in organic chemistry, but presents very practical examples that allow the student to see the obvious link between theory and practice. The examples are described almost as if the author is performing a demonstration in a classvery vivid to the imagination. This is important because students are expected in the future to perform and put into practice their knowledge of food chemistry.

  18. PREFACE: 3rd International Symposium on Functional Materials 2009 (ISFM 2009) 3rd International Symposium on Functional Materials 2009 (ISFM 2009)

    NASA Astrophysics Data System (ADS)

    Kiwon, Kim; Li, Lu; Taehyun, Nam; Jouhyeon, Ahn

    2010-05-01

    The 3rd International Symposium on Functional Materials 2009 (ISFM 2009) and its preconference, Advances in Functional Materials 2009 (AFM 2009), were successfully held in the Republic of Korea from 15-18 June 2009 and in the People's Republic of China from 8-12 June 2009, respectively. The two conferences attracted over 300 oral and poster presentations from over 12 countries including Australia, Canada, China, Germany, Japan, India, Israel, Korea, The Netherlands, Thailand, the UK and the USA. In the two conferences, eight keynote lectures were delivered by S Miyazaki, S A Akbar, D J Singh, C Suryanarayana, M~Greenblatt, H Zhang, T Sato and J Ding. This topical issue of Physica Scripta contains papers presented at the ISFM 2009 and AFM 2009. Keyan Li from Dalian University, People's Republic of China, presents some empirical formulae to estimate the elastic moduli of rocksalt-, zincblende- and chalcopyrite-structured crystals, on the basis of electronegativities of bonded atoms in the crystallographic frame. Min-Jung Kim from Hanyang University, Korea, reports on the preparation and characterization of carboxyl functionalization of magnetite nanoparticles for oligonucleotide immobilization. F Yan from the National University of Singapore studies the fabrication of Bi(Fe0.5Sc0.5)O3-PbTiO3 (BSF-PT) thin films by pulsed laser deposition, and the enhanced magnetic moment with respect to BiFeO3-PbTiO3. Dong-Gil Lee from Pusan National University, Korea, reports on the sterilization of enteropathogenic Escherichia coli using nanofiber TiO2 films prepared by the electrostatic spray method. Sang-Eun Park from the Korea Institute of Science and Technology reports on the study of encapsulated Fe3O4 nanoparticles with a silica thin layer with a reversible capacity of about 363 mAhg-1. Other researchers report on many other exiting achievements in the fields of ferromagnetic materials, magneto-optical materials, thermoelectric materials, shape memory materials, fuel-cell and

  19. The 3rd Canadian Symposium on Hepatitis C Virus: Expanding care in the interferon-free era

    PubMed Central

    MacParland, Sonya A; Bilodeau, Marc; Grebely, Jason; Bruneau, Julie; Cooper, Curtis; Klein, Marina; Sagan, Selena M; Choucha, Norma; Balfour, Louise; Bialystok, Frank; Krajden, Mel; Raven, Jennifer; Roberts, Eve; Russell, Rodney; Houghton, Michael; Tyrrell, D Lorne; Feld, Jordan J

    2014-01-01

    Hepatitis C virus (HCV) currently infects approximately 250,000 individuals in Canada and causes more years of life lost than any other infectious disease in the country. In August 2011, new therapies were approved by Health Canada that have achieved higher response rates among those treated, but are poorly tolerated. By 2014/2015, short-course, well-tolerated treatments with cure rates >95% will be available. However, treatment uptake is poor due to structural, financial, geographical, cultural and social barriers. As such, ‘Barriers to access to HCV care in Canada’ is a crucial topic that must be addressed to decrease HCV disease burden and potentially eliminate HCV in Canada. Understanding how to better care for HCV-infected individuals requires integration across multiple disciplines including researchers, clinical services and policy makers to address the major populations affected by HCV including people who inject drugs, baby boomers, immigrants and Aboriginal and/or First Nations people. In 2012, the National CIHR Research Training Program in Hepatitis C organized the 1st Canadian Symposium on Hepatitis C Virus (CSHCV) in Montreal, Quebec. The 2nd CSHCV was held in 2013 in Victoria, British Columbia. Both symposia were highly successful, attracting leading international faculty with excellent attendance leading to dialogue and knowledge translation among attendees of diverse backgrounds. The current article summarizes the 3rd CSHCV, held February 2014, in Toronto, Ontario. PMID:25314353

  20. 3rd Quarter Transportation Report FY 2014: Radioactive Waste Shipments to and from the Nevada National Security Site (NNSS)

    SciTech Connect

    Gregory, Louis

    2014-09-20

    This report satisfies the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) commitment to prepare a quarterly summary report of radioactive waste shipments to the Nevada National Security Site (NNSS) Radioactive Waste Management Complex (RWMC) at Area 5. There were no shipments sent for offsite treatment and returned to the NNSS this quarter. This report summarizes the 3rd quarter of Fiscal Year (FY) 2014 low-level radioactive waste (LLW) and mixed low-level radioactive waste (MLLW) shipments. This report also includes annual summaries for FY 2014 in Tables 4 and 5. Tabular summaries are provided which include the following: Sources of and carriers for LLW and MLLW shipments to and from the NNSS; Number and external volume of LLW and MLLW shipments; Highway routes used by carriers; and Incident/accident data applicable to LLW and MLLW shipments. In this report shipments are accounted for upon arrival at the NNSS, while disposal volumes are accounted for upon waste burial. The disposal volumes presented in this report do not include minor volumes of non-radioactive materials that were approved for disposal. Volume reports showing cubic feet generated using the Low-Level Waste Information System may vary slightly due to differing rounding conventions.

  1. To keep the catch – that is the question: a personal account of the 3rd Annual EULAR Congress, Stockholm

    PubMed Central

    Wollheim, Frank A

    2002-01-01

    The 3rd Annual EULAR Congress, held in Stockholm on 12–15 June 2002, had a turnout of 8300 delegates, almost identical to last year's record attendance level in Prague. The venue was close to ideal, allowing ample space for poster sessions in the exhibition hall. The manned poster sessions were well attended, even on the last day of the Congress. The numerous invited speakers represented the world's elite, allowing the staging of excellent state-of-the-art podium sessions. The aim of attracting the young scientific community was partly achieved, but individual delegates' dependence on industry sponsorship poses potential problems. The organization was a big improvement compared to that of the two previous congresses. Approximately 1800 abstracts were submitted, an increase of 50%, resulting in a higher quality of accepted abstracts. The satellite symposia held every morning and late afternoon were well attended; thus, industry exposure of new products, both in podium sessions and at the exhibitions, was well accommodated. The Annual EULAR Congress consolidates its position as one of the two most important annual congresses of rheumatology, but EULAR economy and commercial aspects are still too dominant in relation to science. PMID:12223107

  2. Simulation of robustness of a new e-beam column with the 3 rd-order imaging technique

    NASA Astrophysics Data System (ADS)

    Takeya, K.; Fuse, T.; Kinoshita, H.; Parker, N. William

    2008-03-01

    We are now investigating a new concept column with the 3 rd-order imaging technique, in order to obtain fine resolution and high current density beams for electron beam direct writing (EBDW) suitable for below 32nm technology nodes. From the first experimental verification, it is found that the 3 rd-order imaging has a benefit of increasing the beam current compared with conventional Gaussian beam without any beam blurring. However, in order to realize such a column which can work stably in the sub 32nm technology node generations, it is important to clarify how robust the 3 rd-order imaging is against the mechanical tolerances in column manufacturing. This paper describes the tolerance analysis for errors of column manufacturing by simulation. The column has an electron gun with small virtual source and two (Gun and Main) lenses. A patterned beam defining aperture, which enables the 3 rd-order imaging, is set between the 1 st and the 2 nd lenses. The influences of errors such as concentricity, offset and tilt between optical parts on the beam shape, beam current density distribution, and beam edge acuity on a wafer is analyzed for this column. According to these results, the 3 rd-order imaging appears to have sufficiently large allowance compared to the error budget for column manufacturing required in the sub 32nm technology node patterning.

  3. Five Years of Tamoxifen Continues to Benefit Women 15 Years after Treatment

    Cancer.gov

    In a large randomized clinical trial, women with early-stage breast cancer who received 5 years of adjuvant treatment with tamoxifen had better outcomes up to 15 years after the start of treatment than those who received 2 years of tamoxifen therapy.

  4. [Level of smoking of 3rd and 4th grade students studying health and related factors: follow-up study].

    PubMed

    Göktalay, Tuğba; Cengiz Özyurt, Beyhan; Sakar Coşkun, Ayşin; Celik, Pinar

    2011-01-01

    The levels of smoking of 1st and 2nd year students at Faculty of Medicine and Manisa School of Health at Celal Bayar University were investigated in 2006-2007. This study is carried out in order to see if there is a change in the same students' level of smoking while they are in 3rd and 4th year. In addition, the study aimed to examine the factors affecting the level of use and attitudes towards the law effectuated in July 19, 2009. This is a follow-up study with 80.42% return rate. A 26-item structured questionnaire was administered. The participants filled out the questionnaires under supervision of the researchers in their classrooms. The University Institutional Review Board approved the study. The total of participants (263) of the follow-up study included 189 female and 74 male. The rate of experimenting with smoking was 49% with the mean age of 15.7 (SD= 4.01 years). The mean age of experimenting with smoking was the earliest on male students studying at faculty of medicine. The level of smoking was found to be the most on females, studying at faculty of medicine and staying at the dormitory, with smoking parents (p< 0.05). The most important reason to begin smoking was curiosity (55.2%) while bad breath and yellowing of teeth were the reasons to quit (91.7%). 83.3% of the students thought that the law will be effective on quit smoking. The level of both experimenting and use of smoking has been increased over time. It is suggested that medical students' awareness about the danger of smoking should be raised at earlier grades. In addition, lectures should be offered to students at School of Health and they should be encouraged to unite in order to fight with smoking.

  5. [Level of smoking of 3rd and 4th grade students studying health and related factors: follow-up study].

    PubMed

    Göktalay, Tuğba; Cengiz Özyurt, Beyhan; Sakar Coşkun, Ayşin; Celik, Pinar

    2011-01-01

    The levels of smoking of 1st and 2nd year students at Faculty of Medicine and Manisa School of Health at Celal Bayar University were investigated in 2006-2007. This study is carried out in order to see if there is a change in the same students' level of smoking while they are in 3rd and 4th year. In addition, the study aimed to examine the factors affecting the level of use and attitudes towards the law effectuated in July 19, 2009. This is a follow-up study with 80.42% return rate. A 26-item structured questionnaire was administered. The participants filled out the questionnaires under supervision of the researchers in their classrooms. The University Institutional Review Board approved the study. The total of participants (263) of the follow-up study included 189 female and 74 male. The rate of experimenting with smoking was 49% with the mean age of 15.7 (SD= 4.01 years). The mean age of experimenting with smoking was the earliest on male students studying at faculty of medicine. The level of smoking was found to be the most on females, studying at faculty of medicine and staying at the dormitory, with smoking parents (p< 0.05). The most important reason to begin smoking was curiosity (55.2%) while bad breath and yellowing of teeth were the reasons to quit (91.7%). 83.3% of the students thought that the law will be effective on quit smoking. The level of both experimenting and use of smoking has been increased over time. It is suggested that medical students' awareness about the danger of smoking should be raised at earlier grades. In addition, lectures should be offered to students at School of Health and they should be encouraged to unite in order to fight with smoking. PMID:22233305

  6. TEC obtained from 3rd Stokes parameter for improved quality of SMOS salinity retrieval

    NASA Astrophysics Data System (ADS)

    Vergely, Jean-Luc; Waldteufel, Philippe; Boutin, Jacqueline; Yin, Xiaobin; Spurgeon, Paul

    2014-05-01

    While SMOS was designed with full polarimetric capability, the 3rd Stokes parameter information has not been introduced so far in the data processing. The analysis reported in the present contribution proposes to estimate from this information the total ionospheric electron content (TEC). Indeed the Faraday effect generated by the ionospheric electrons on the path from Earth to satellite is believed to be responsible for large uncertainties in the evening half-orbits (circa 06 PM local time) when the ionospheric content is close to its diurnal maximum. It is shown that the 3rd Stokes parameter exhibits a maximal sensitivity to TEC in a restricted area located at the front of the SMOS 2D field of view. However, since the Faraday angle depends on the scalar product between line-of-sight and magnetic field vectors, a latitudinal zone is found where this sensitivity vanishes. This zone occurs around 15° N a latitude nearly invariant with longitude around the Earth. Accordingly it is possible, when carrying out the TEC estimation over a descending half-orbit, to isolate over this "blind zone" the so-called "Ocean Target Transformation" parameter, which aims at correcting for pixel dependent biases. TEC maps obtained in this way compare favorably with maps built from GPS measurements, which have been introduced so far in the SMOS processing chain as auxiliary data. The space resolution is somewhat improved, allowing a better selection of the relevant electron content in zones exhibiting large horizontal TEC gradients. In a latter step, based on the TEC maps, it becomes possible to recompute the OTT correction for those brightness temperature components to be used as input in the salinity retrieval. Then the additional information impacts the salinity retrieval both directly (as the quality of the TEC auxiliary data is improved) and indirectly (as the empirical OTT correction is no longer contaminated by spurious Faraday rotation effects). The respective contributions of

  7. Classification of biliary tract cancers established by the Japanese Society of Hepato-Biliary-Pancreatic Surgery: 3(rd) English edition.

    PubMed

    Miyazaki, Masaru; Ohtsuka, Masayuki; Miyakawa, Shuichi; Nagino, Masato; Yamamoto, Masakazu; Kokudo, Norihiro; Sano, Keiji; Endo, Itaru; Unno, Michiaki; Chijiiwa, Kazuo; Horiguchi, Akihiko; Kinoshita, Hisafumi; Oka, Masaaki; Kubota, Keiichi; Sugiyama, Masanori; Uemoto, Shinji; Shimada, Mitsuo; Suzuki, Yasuyuki; Inui, Kazuo; Tazuma, Susumu; Furuse, Junji; Yanagisawa, Akio; Nakanuma, Yasuni; Kijima, Hiroshi; Takada, Tadahiro

    2015-03-01

    The 3(rd) English edition of the Japanese classification of biliary tract cancers was released approximately 10 years after the 5(th) Japanese edition and the 2(nd) English edition. Since the first Japanese edition was published in 1981, the Japanese classification has been in extensive use, particularly among Japanese surgeons and pathologists, because the cancer status and clinical outcomes in surgically resected cases have been the main objects of interest. However, recent advances in the diagnosis, management and research of the disease prompted the revision of the classification that can be used by not only surgeons and pathologists but also by all clinicians and researchers, for the evaluation of current disease status, the determination of current appropriate treatment, and the future development of medical practice for biliary tract cancers. Furthermore, during the past 10 years, globalization has advanced rapidly, and therefore, internationalization of the classification was an important issue to revise the Japanese original staging system, which would facilitate to compare the disease information among institutions worldwide. In order to achieve these objectives, the new Japanese classification of the biliary tract cancers principally adopted the 7(th) edition of staging system developed by the International Union Against Cancer (UICC) and the American Joint Committee on Cancer (AJCC). However, because there are some points pending in these systems, several distinctive points were also included for the purpose of collection of information for the future optimization of the staging system. Free mobile application of the new Japanese classification of the biliary tract cancers is available via http://www.jshbps.jp/en/classification/cbt15.html. PMID:25691463

  8. Classification of biliary tract cancers established by the Japanese Society of Hepato-Biliary-Pancreatic Surgery: 3(rd) English edition.

    PubMed

    Miyazaki, Masaru; Ohtsuka, Masayuki; Miyakawa, Shuichi; Nagino, Masato; Yamamoto, Masakazu; Kokudo, Norihiro; Sano, Keiji; Endo, Itaru; Unno, Michiaki; Chijiiwa, Kazuo; Horiguchi, Akihiko; Kinoshita, Hisafumi; Oka, Masaaki; Kubota, Keiichi; Sugiyama, Masanori; Uemoto, Shinji; Shimada, Mitsuo; Suzuki, Yasuyuki; Inui, Kazuo; Tazuma, Susumu; Furuse, Junji; Yanagisawa, Akio; Nakanuma, Yasuni; Kijima, Hiroshi; Takada, Tadahiro

    2015-03-01

    The 3(rd) English edition of the Japanese classification of biliary tract cancers was released approximately 10 years after the 5(th) Japanese edition and the 2(nd) English edition. Since the first Japanese edition was published in 1981, the Japanese classification has been in extensive use, particularly among Japanese surgeons and pathologists, because the cancer status and clinical outcomes in surgically resected cases have been the main objects of interest. However, recent advances in the diagnosis, management and research of the disease prompted the revision of the classification that can be used by not only surgeons and pathologists but also by all clinicians and researchers, for the evaluation of current disease status, the determination of current appropriate treatment, and the future development of medical practice for biliary tract cancers. Furthermore, during the past 10 years, globalization has advanced rapidly, and therefore, internationalization of the classification was an important issue to revise the Japanese original staging system, which would facilitate to compare the disease information among institutions worldwide. In order to achieve these objectives, the new Japanese classification of the biliary tract cancers principally adopted the 7(th) edition of staging system developed by the International Union Against Cancer (UICC) and the American Joint Committee on Cancer (AJCC). However, because there are some points pending in these systems, several distinctive points were also included for the purpose of collection of information for the future optimization of the staging system. Free mobile application of the new Japanese classification of the biliary tract cancers is available via http://www.jshbps.jp/en/classification/cbt15.html.

  9. Effects of notetaking instruction on 3rd grade student's science learning and notetaking behavior

    NASA Astrophysics Data System (ADS)

    Lee, Pai-Lin

    The research examined effects of notetaking instruction on elementary-aged students' ability to recall science information and notetaking behavior. Classes of 3rd grade students were randomly assigned to three treatment conditions, strategic notetaking, partial strategic notetaking, and control, for 4 training sessions. The effects of the notetaking instruction were measured by their performances on a test on science information taught during the training, a long-term free recall of the information, and number of information units recalled with or without cues. Students' prior science achievement was used to group students into two levels (high vs. low) and functioned as another independent variable in analysis. Results indicated significant treatment effect on cued and non-cued recall of the information units in favor of the strategy instruction groups. Students with higher prior achievement in science performed better on cued recall and long-term free recall of information. The results suggest that students as young as at the third grade can be instructed to develop the ability of notetaking that promotes their learning.

  10. The 3^rd International Conference on Women in Physics: Global Perspectives, Common Concerns, Worldwide Views

    NASA Astrophysics Data System (ADS)

    Zastavker, Yevgeniya V.

    2009-03-01

    The 3^rd International Conference on Women in Physics (ICWIP), held in Seoul, Korea, in October 2008, brought together 300 participants from 57 countries, including a diverse 22-member U.S. Delegation, for a 3-day summit of stimulating discussions, thought-provoking presentations, inspirational posters, and networking. Held under the auspices of the Working Group on Women in Physics of the International Union of Pure and Applied Physics (IUPAP), this meeting built on the successes of the 1^st (Paris, 2002) and 2^nd (Rio de Janeiro, 2005) Conferences and further clarified the importance of diversifying the field of physics worldwide. Although considerable progress has been made since 2002, it was clear that the global scientific workforce is still under-utilizing a large percentage of the available female talent pool. If human society is to benefit to its fullest from various contributions that the field of physics can offer in addressing global issues of economic crisis, energy, environment, water, health, poverty, and hunger, women of all races and nationalities need to become fully included and engaged in the national and international physical community. To address these and many other issues, the ICWIP unanimously approved a five-part resolution to IUPAP recommending actions to promote the recruitment, retention, and advancement of women in physics and related fields.

  11. Measuring the cascade rate in anisotropic turbulence through 3rd order structure functions.

    NASA Astrophysics Data System (ADS)

    Verdini, Andrea; Landi, Simone; Hellinger, Petr

    2014-05-01

    We employ the Von-Karman-Howart-Yaglom-Politano-Poquet (KHYPP)law, to compute the cascade rate by means of 3rd order structure functions in homogeneous, forced, DNS at high resolution. We consider first the isotropic case (no guide field) and verify that the cascade rate is consistent with the dissipation rate. Then we consider an anisotropic case (with guide field) for which the isotropic KHYPP law does not apply. We compute the parallel and perpendicular cascade rates and find that the latter basically accounts for the total dissipation rate, as expected for anisotropic turbulence. Also, the cascade rate derived from the isotropic law is found to be a good approximation for the total cascade rate. Recent works have shown that the hypothesis of stationary turbulence must be probably relaxed in the solar wind. We present preliminary results on the measure of the cascade rate in the expanding solar wind, obtained with DNS of MHD turbulence in the expanding box model. Such model incorporates the basic physic of expansion thus inducing anisotropies driven by both the magnetic field and expansion, along with an energy decrease due to the conservation of linear invariants (angular momentum and magnetic flux). The correction due to non-stationary conditions is found to be important and to become negligible only at small scales, thus suggesting that solar wind measurements over- estimate the actual cascade rate.

  12. Measurement and correction of the 3rd order resonance in the Tevatron

    SciTech Connect

    Schmidt, F.; Alexahin, Y.; Lebedev, V.; Still, D.; Valishev, A.; /Fermilab

    2006-06-01

    At Fermilab Tevatron BPM system has been recently upgraded resulting much better accuracy of beam position measurements and improvements of data acquisition for turn-by-turn measurements. That allows one to record the beam position at each turn for 8000 turns for all BPMs (118 in each plane) with accuracy of about 10-20 {micro}m. In the last decade a harmonic analysis tool has been developed at CERN that allows relating each FFT line derived from the BPM data with a particular non-linear resonance in the machine. In fact, one can even detect the longitudinal position of the sources of these resonances. Experiments have been performed at the Tevatron in which beams have been kicked to various amplitudes to analyze the 3rd order resonance. It was possible to address this rather large resonance to some regular machine sextupoles. An alternative sextupole scheme allowed the suppression of this resonance by a good factor of 2. Lastly, the experimental data are compared with model calculations.

  13. Visual, Critical, and Scientific Thinking Dispositions in a 3rd Grade Science Classroom

    NASA Astrophysics Data System (ADS)

    Foss, Stacy

    Many American students leave school without the required 21st century critical thinking skills. This qualitative case study, based on the theoretical concepts of Facione, Arheim, and Vygotsky, explored the development of thinking dispositions through the arts in science on the development of scientific thinking skills when used as a conceptual thinking routine in a rural 3rd grade classroom. Research questions examined the disposition to think critically through the arts in science and focused on the perceptions and experiences of 25 students with the Visual Thinking Strategy (VTS) process. Data were collected from classroom observations (n = 10), student interviews (n = 25), teacher interviews ( n = 1), a focus group discussion (n = 3), and artifacts of student work (n = 25); these data included perceptions of VTS, school culture, and classroom characteristics. An inductive analysis of qualitative data resulted in several emergent themes regarding disposition development and students generating questions while increasing affective motivation. The most prevalent dispositions were open-mindedness, the truth-seeking disposition, the analytical disposition, and the systematicity disposition. The findings about the teachers indicated that VTS questions in science supported "gradual release of responsibility", the internalization of process skills and vocabulary, and argumentation. This case study offers descriptive research that links visual arts inquiry and the development of critical thinking dispositions in science at the elementary level. A science curriculum could be developed, that emphasizes the development of thinking dispositions through the arts in science, which in turn, could impact the professional development of teachers and learning outcomes for students.

  14. Resurgence of duckweed research and applications: report from the 3rd International Duckweed Conference.

    PubMed

    Appenroth, Klaus-J; Sree, K Sowjanya; Fakhoorian, Tamra; Lam, Eric

    2015-12-01

    Duckweed, flowering plants in the Lemnaceae family, comprises the smallest angiosperms in the plant kingdom. They have some of the fastest biomass accumulation rates reported to date for plants and have the demonstrated ability to thrive on wastewater rich in dissolved organic compounds and thus could help to remediated polluted water resources and prevents eutrophication. With a high quality genome sequence now available and increased commercial interest worldwide to develop duckweed biomass for renewables such as protein and fuel, the 3rd International Duckweed Conference convened at Kyoto, Japan, in July of 2015, to update the community of duckweed researchers and developers on the progress in the field. In addition to sharing results and ideas, the conference also provided ample opportunities for new-comers as well as established workers in the field to network and create new aliances. We hope this meeting summary will also help to disseminate the key advances and observations that have been presented in this conference to the broader plant biology community in order to encourage increased cross-fertilization of ideas and technologies. PMID:26506824

  15. Resurgence of duckweed research and applications: report from the 3rd International Duckweed Conference.

    PubMed

    Appenroth, Klaus-J; Sree, K Sowjanya; Fakhoorian, Tamra; Lam, Eric

    2015-12-01

    Duckweed, flowering plants in the Lemnaceae family, comprises the smallest angiosperms in the plant kingdom. They have some of the fastest biomass accumulation rates reported to date for plants and have the demonstrated ability to thrive on wastewater rich in dissolved organic compounds and thus could help to remediated polluted water resources and prevents eutrophication. With a high quality genome sequence now available and increased commercial interest worldwide to develop duckweed biomass for renewables such as protein and fuel, the 3rd International Duckweed Conference convened at Kyoto, Japan, in July of 2015, to update the community of duckweed researchers and developers on the progress in the field. In addition to sharing results and ideas, the conference also provided ample opportunities for new-comers as well as established workers in the field to network and create new aliances. We hope this meeting summary will also help to disseminate the key advances and observations that have been presented in this conference to the broader plant biology community in order to encourage increased cross-fertilization of ideas and technologies.

  16. Exploiting stem cell therapy: the 3rd meeting of stem cell research Italy.

    PubMed

    Di Bernardo, Giovanni; Piva, Roberta; Giordano, Antonio; Galderisi, Umberto

    2013-04-01

    The study of stem cells is one of the most exciting areas of contemporary biomedical research. During the 3rd Joint Meeting of Stem Cell Research Italy (June 2012, Ferrara, Italy), scientists from different multidisciplinary areas explored new frontiers of basic and applied stem cell research with key lectures and oral presentations. There was a public debate on ethics during the opening ceremony, specifically on the limits and potentialities of adult and embryonic stem cells. Some scientists presented basic research data showing evolutionary aspects, which could be of interest in understanding specific biological phenomena. Others focused on "dangerous liaisons" between gene transfer vectors and the human genome. Some speakers provided insight into current stem cell therapies, such as those involving human epithelial stem cells for treatment of skin diseases. Other researchers presented data on close-to-therapy findings, such as the use of mesenchymal stem cells in brain repair. Of note, during the meeting, spotlights were focused on major issues that have to be considered for GMP stem cell production for cell therapy. In "Meet the Expert" sessions, specialists presented innovative technologies such as a next-generation sequencing system. Finally, the meeting provided an excellent opportunity for young scientists to show their findings, and to discuss with each other and with internationally recognized experts.

  17. Constancy and Variability: Dialogic Literacy Events as Sites for Improvisation in Two 3rd-Grade Classrooms

    ERIC Educational Resources Information Center

    Jordan, Michelle E.; Santori, Diane

    2015-01-01

    This multisite study investigates dialogic literacy events that revolved around narrative and informational texts in two 3rd-grade classrooms. The authors offer a metaphor of musical improvisation to contemplate dialogic literacy events as part of the repertoire of teaching and learning experiences. In literacy learning, where there is much…

  18. The Lived Experiences of 3rd Generation and beyond U.S.-Born Mexican Heritage College Students: A Qualitative Study

    ERIC Educational Resources Information Center

    Galvan, Richard

    2011-01-01

    The purpose of this study was to describe the psychosocial and identity challenges of 3rd generation and beyond U.S.-born (3GAB-USB) Mexican heritage college students. Alvarez (1973) has written about the psychosocial impact "hybridity" can have on a U.S.- born (USB) Mexican individual who incorporates two distinct cultures (American and Mexican)…

  19. Iron metabolism in African American women during the 2nd and 3rd trimester of a high-risk pregnancy

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Objective: To examine iron metabolism during the 2nd and 3rd trimester in African American women classified as a high-risk pregnancy. Design: Longitudinal. Setting: Large, university-based, urban Midwestern medical center. Participants: Convenience sample of 47 African American women classified a...

  20. A Program Evaluation of ClassScape Used in 3rd Grade Classes in a Rural County in North Carolina

    ERIC Educational Resources Information Center

    Rogers, Misha Neely

    2012-01-01

    The research study will examine the impact of using the ClassScape program and targeted interventions on 3rd grade reading levels of performance. The conceptual and theoretical framework for the study suggests the need to connect formative, benchmark, and summative assessments in North Carolina. Furthermore, the review of the literature will…

  1. 3rd Annual PIALA Conference Saipan--Collecting, Preserving & Sharing Information in Micronesia. Conference Proceedings. October 13-15, 1993.

    ERIC Educational Resources Information Center

    Edmundson, Margaret, Ed.

    1993-01-01

    This PIALA 1993 Proceedings contains many of the papers presented at the 3rd annual conference of the Pacific Islands Association of Libraries and Archives. This publication is the first time papers from this Micronesian regional library and archives conference have ever been published. The conference addressed various topics of interest to…

  2. Continuity and Change in General Cognitive Ability from 1 to 7 years of Age.

    ERIC Educational Resources Information Center

    Cardon, Lon R.; And Others

    1992-01-01

    Yearly cognitive tests were administered to adoptive and nonadoptive siblings between one and seven years of age and identical and nonidentical twins between one and three years. Results indicated that genetic influences are a source of continuity and change in mental development, whereas shared and nonshared environmental effects contribute to…

  3. [A continuous 4-year evaluation of medical informatics education in a graduate school of health sciences using a questionnaire survey].

    PubMed

    Monzen, Satoru; Matsutani, Hideya; Kashiwakura, Ikuo

    2013-01-01

    The purpose of this study was to identify the level of awareness among undergraduate students regarding medical informatics and to ascertain whether educational training has progressed with time in the Department of Health Sciences at Hirosaki University, Japan, which is a co-medical staff training institution that conducts a 4-year university course in medical informatics. The university accepts students who have completed the 3rd grade of medical licensing tests and who have attended the medical informatics lectures for 4 years (2007-2010). The ratio of first sight terminology percentage in any given fiscal year in all the 30 terminology categories varied widely from 0% to 80%, but the trend in various categories did not vary between fiscal years. The terminology of informatics under medical technology students obtained high scores of 52.5-77.3% after attending courses, which was higher compared with students from other classes. On the other hand, student nurses and occupational therapy students obtained 0-44.2%. Each class scored a high percentage of correct answers in the medical information-related terminology. Among the radiology students who attended the classes, the percentage of correct answers in categories of "digital imaging and communication in medicine" and "picture archiving and communication system" were lower than other medical terminology categories. These results reflect the gaps in educational curriculum of 1st and 2nd grades of medical licensing tests. PMID:23358336

  4. [A continuous 4-year evaluation of medical informatics education in a graduate school of health sciences using a questionnaire survey].

    PubMed

    Monzen, Satoru; Matsutani, Hideya; Kashiwakura, Ikuo

    2013-01-01

    The purpose of this study was to identify the level of awareness among undergraduate students regarding medical informatics and to ascertain whether educational training has progressed with time in the Department of Health Sciences at Hirosaki University, Japan, which is a co-medical staff training institution that conducts a 4-year university course in medical informatics. The university accepts students who have completed the 3rd grade of medical licensing tests and who have attended the medical informatics lectures for 4 years (2007-2010). The ratio of first sight terminology percentage in any given fiscal year in all the 30 terminology categories varied widely from 0% to 80%, but the trend in various categories did not vary between fiscal years. The terminology of informatics under medical technology students obtained high scores of 52.5-77.3% after attending courses, which was higher compared with students from other classes. On the other hand, student nurses and occupational therapy students obtained 0-44.2%. Each class scored a high percentage of correct answers in the medical information-related terminology. Among the radiology students who attended the classes, the percentage of correct answers in categories of "digital imaging and communication in medicine" and "picture archiving and communication system" were lower than other medical terminology categories. These results reflect the gaps in educational curriculum of 1st and 2nd grades of medical licensing tests.

  5. Department of Defense and Full-Year Continuing Appropriations Act, 2011

    THOMAS, 112th Congress

    Rep. Rogers, Harold [R-KY-5

    2011-04-11

    04/15/2011 Became Public Law No: 112-10. (TXT | PDF) (All Actions) Notes: Division A: Department of Defense Appropriations. Division B: Full-Year Continuing Appropriations, continuing appropriations through 9/30/2011. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  6. PREFACE: 3rd International Youth Conference "Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology" (Nanobiotech 2015)

    NASA Astrophysics Data System (ADS)

    Refsnes, Magne, Prof; Gusev, Alexander, Dr; Godymchuk, Anna, Dr; Bogdan, Anna

    2015-11-01

    The 3rd International Youth Conference "Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology" (Nanobiotech2015) was held on 21-22 May 2015 in Tambov, Russia, and was jointly organized by Tambov Derzhavin State University (Russia), the Norwegian Institute of Public Health (Norway), the National University of Science and Technology MISiS (Russia), Tomsk Polytechnic University (Russia) and Tomsk State University. The conference gathered experienced and young researchers, post-docs and students, working in the fieldof nanotechnologies, nanomedicine, nano(eco)toxicology and risk assessment of nanomaterials, in order to facilitate the aggregation and sharing of interests and results for better collaboration and visibility of activity. The goal of Nanobiotech2015 was to bring researchers and practitioners together to share the latest knowledge on nanotechnology-specific risks to occupational and environmental health and assessing how to reduce these potential risks. The main objective of the conference is to identify, systematize and solve current scientific problems inthe sphere of nanobiotechnologies, nanomedicine and nanotoxicology, in order to join forces todetermine prospective areas and compose working groups of interested co-workers for carrying out interdisciplinary research projects. The topics of Nanobiotech2015 were: (1) Nanotechnologies in pharmaceutics and medicine; (2) Sources and mechanisms of nanoparticle release into the environment; (3) Ecological and biological effects of nanoparticles; (4) (Eco)toxicology of nanomaterials; (5) Methods for detection of nanoparticles in the environment and in biological objects; and (6) Physico-chemical properties of nanoparticles in the environment. We want to thank the Organizing Committee, the universities and sponsors supporting the conference,and everyone who contributed to the organization of this meeting, for their contribution towards the conference and for their contributions to these

  7. NASA's Sun-Earth Connection Theory Program - into 3rd Decade

    NASA Astrophysics Data System (ADS)

    Grebowsky, J. M.

    2002-12-01

    NASA's Sun-Earth Connection Theory Program (SECTP) is now in its first year of a new triennial cycle of funded research, with all the research awards beginning in 2002. The focus of the current research efforts and the accomplishments of the previous 3-year (1998-2001) cycle of research, just terminating, will be described. The SECTP, formerly the Space Physics Theory Program (SPTP), was initially established by the (former) Solar Terrestrial Division in 1980 to redress a weakness of support in the theory area. It has been a successful evolving scientific program for long-term funding of relatively large "critical mass groups" pursuing theory and modeling on a scale larger than that available within the limits of traditional NASA Supporting Research and Technology (SR&T) awards. The results of the program over the years has contributed to ever more cutting edge theoretical understanding of all parts of the Sun-Earth Connection chain, from the core of the sun out into the corona, through the solar wind into the Earth's magnetosphere and down to the ionosphere and lower atmosphere. In addition, it continues to support the development of more and more realistic computer models that have become the workhorses for analyzing satellite and ground-based measurements and in helping to plan and implement NASA spacecraft missions. The focus of the program and the applications of its research results are viewed in this paper from the perspective of recent program activities.

  8. Teacher Transition between Year Levels in Primary Schools: An Opportunity for Continuing Professional Development

    ERIC Educational Resources Information Center

    Carlyon, Tracey

    2015-01-01

    Teacher transition between year levels is common practice in many primary schools in New Zealand; however, it is not always perceived as an opportunity for teachers' continuing professional development (CPD). This article reports on a case study that explored four primary school teachers' experiences of transition between year levels. The teachers…

  9. PreK-3rd: Raising the Educational Performance of English Language Learners (ELLs). PreK-3rd Policy to Action Brief. No. Six

    ERIC Educational Resources Information Center

    Russakoff, Dale

    2011-01-01

    In 1974, the United States Supreme Court ruled in "Lau v. Nichols" that 1,800 Chinese-speaking children in the San Francisco public schools were entitled to English-language instruction or other support to help them understand what was happening in their classrooms. Thirty-six years later, state and local responsibilities to public school children…

  10. ic-cmtp3: 3rd International Conference on Competitive Materials and Technology Processes

    NASA Astrophysics Data System (ADS)

    2016-04-01

    Competitiveness is one of the most important factors in our lives and it plays a key role in the efficiency both of organizations and societies. The more scientifically advanced and prepared organizations develop more competitive materials with better physical, chemical, and biological properties, and the leading companies apply more competitive equipment and technological processes. The aims of the 3rd International Conference on Competitive Materials and Technology Processes (ic-cmtp3), and the 1st International Symposium on Innovative Carbons and Carbon Based Materials (is-icbm1) and the 1st International Symposium on Innovative Construction Materials (is-icm1) organized alongside are the following: —Promote new methods and results of scientific research in the fields of material, biological, environmental and technological sciences; —Exchange information between the theoretical and applied sciences as well as technical and technological implementations; —Promote communication and collaboration between the scientists, researchers and engineers of different nations, countries and continents. Among the major fields of interest are advanced and innovative materials with competitive characteristics, including mechanical, physical, chemical, biological, medical and thermal, properties and extreme dynamic strength. Their crystalline, nano - and micro-structures, phase transformations as well as details of their technological processes, tests and measurements are also in the focus of the ic-cmtp3 conference and the is-scbm1 and is-icm1 symposia. Multidisciplinary applications of material science and the technological problems encountered in sectors like ceramics, glasses, thin films, aerospace, automotive and marine industries, electronics, energy, construction materials, medicine, biosciences and environmental sciences are of particular interest. In accordance with the program of the ic-cmtp3 conference and is-icbm1 and is-icm1 symposia we have received more

  11. PREFACE: 3rd International Workshop on Statistical Physics and Mathematics for Complex Systems (SPMCS 2012)

    NASA Astrophysics Data System (ADS)

    Tayurskii, Dmitrii; Abe, Sumiyoshi; Alexandre Wang, Q.

    2012-11-01

    The 3rd International Workshop on Statistical Physics and Mathematics for Complex Systems (SPMCS2012) was held between 25-30 August at Kazan (Volga Region) Federal University, Kazan, Russian Federation. This workshop was jointly organized by Kazan Federal University and Institut Supérieur des Matériaux et Mécaniques Avancées (ISMANS), France. The series of SPMCS workshops was created in 2008 with the aim to be an interdisciplinary incubator for the worldwide exchange of innovative ideas and information about the latest results. The first workshop was held at ISMANS, Le Mans (France) in 2008, and the third at Huazhong Normal University, Wuhan (China) in 2010. At SPMCS2012, we wished to bring together a broad community of researchers from the different branches of the rapidly developing complexity science to discuss the fundamental theoretical challenges (geometry/topology, number theory, statistical physics, dynamical systems, etc) as well as experimental and applied aspects of many practical problems (condensed matter, disordered systems, financial markets, chemistry, biology, geoscience, etc). The program of SPMCS2012 was prepared based on three categories: (i) physical and mathematical studies (quantum mechanics, generalized nonequilibrium thermodynamics, nonlinear dynamics, condensed matter physics, nanoscience); (ii) natural complex systems (physical, geophysical, chemical and biological); (iii) social, economical, political agent systems and man-made complex systems. The conference attracted 64 participants from 10 countries. There were 10 invited lectures, 12 invited talks and 28 regular oral talks in the morning and afternoon sessions. The book of Abstracts is available from the conference website (http://www.ksu.ru/conf/spmcs2012/?id=3). A round table was also held, the topic of which was 'Recent and Anticipated Future Progress in Science of Complexity', discussing a variety of questions and opinions important for the understanding of the concept of

  12. Building monument materials during the 3rd-4rd millennium (Portugal)

    NASA Astrophysics Data System (ADS)

    Moita, Patricia; Pedro, Jorge; Boaventura, Rui; Mataloto, Rui; Maximo, Jaime; Almeida, Luís; Nogueira, Pedro

    2014-05-01

    Dolmens are the most conspicuous remains of the populations of the 4th and first half of 3rd millennia BCE. These tombs are impressive not only for their monumentality, but also because of the socioeconomic investment they represent for those Neolithic communities, namely from the Central-South of Portugal, who built them. Although dolmens have been studied for their funerary content and typologies, an interdisciplinary approach toward the geological characterization and sourcing of stones used in these constructions has not received enough attention from researchers. With MEGAGEO project a multidisciplinary group of geologist and archaeologists intends to assess the relationship between the distribution of dolmens in Central-South Portugal, their source materials, and the geological landscape. GIS will map the information gathered and will be used to analyse these relationships. The selection of the areas, with distinctive geologies (limestone vs granite), will allow to verify if human patterns of behaviour regarding the selection of megaliths are similar or different regionally. Geologically the first target area (Freixo, Alentejo) is dominated by a small intrusion of gabbro mingled/mixed within a granodioritic intrusion both related with variscan orogeny. Granodiorite exhibit several enclaves of igneous and metamorphic nature attesting the interaction between both igneous rocks as well with enclosing gneisses. Despite Alentejo region have a reduced number of outcrops the granodiorite provides rounded to tabular metric blocks. The gabbro is very coarse grained, sometimes with a cumulate texture, and their fracturing and weathering provide very fresh tabular blocks. The five studied dolmens (Quinta do Freixo #1 to #5) are implanted in a large granodioritic intrusion, around the gabbroic rocks, within an area of approximately 9km2. The medium grained granodiorite is ubiquity in all the dolmens slabs and occasionally it can be observed features of mixing and

  13. Limbic system development underlies the emergence of classical fear conditioning during the 3rd and 4th weeks of life in the rat

    PubMed Central

    Deal, Alex L.; Erickson, Kristen J.; Shiers, Stephanie I.; Burman, Michael A.

    2016-01-01

    Classical fear conditioning creates an association between an aversive stimulus and a neutral stimulus. Although the requisite neural circuitry is well understood in mature organisms, the development of these circuits is less well studied. The current experiments examine the ontogeny of fear conditioning and relate it to neuronal activation assessed through immediate early gene (IEG) expression in the amygdala, hippocampus, perirhinal cortex, and hypothalamus of periweanling rats. Rat pups were fear conditioned, or not, during the 3rd or 4th weeks of life. Neuronal activation was assessed by quantifying expression of FBJ osteosarcoma oncogene (FOS) using immunohistochemistry (IHC) in Experiment 1. Fos and early growth response gene-1 (EGR1) expression was assessed using qRT-PCR in Experiment 2. Behavioral data confirm that both auditory and contextual fear continue to emerge between PD 17 and 24. The IEG expression data are highly consistent with these behavioral results. IHC results demonstrate significantly more FOS protein expression in the basal amygdala of fear conditioned PD 23 subjects compared to control subjects, but no significant difference at PD 17. qRT-PCR results suggest specific activation of the amygdala only in older subjects during auditory fear expression. A similar effect of age and conditioning status was also observed in the perirhinal cortex during both contextual and auditory fear expression. Overall, the development of fear conditioning occurring between the 3rd and 4th weeks of life appears to be at least partly attributable to changes in activation of the amygdala and perirhinal cortex during fear conditioning or expression. PMID:26820587

  14. Does 3rd Age + 3rd World = 3rd Class?

    ERIC Educational Resources Information Center

    Tout, Ken

    1992-01-01

    Demographic changes, migration, and industrialization are having drastic effects on older adults in developing nations. Local programs such as Pro Vida in Colombia, supported by Help Age International, rely on the support of volunteers to improve the quality of life for elderly people. (SK)

  15. Effect on Physical Activity of a Randomized Afterschool Intervention for Inner City Children in 3rd to 5th Grade

    PubMed Central

    Crouter, Scott E.; de Ferranti, Sarah D.; Whiteley, Jessica; Steltz, Sarah K.; Osganian, Stavroula K.; Feldman, Henry A.; Hayman, Laura L.

    2015-01-01

    Background Less than 45% of U.S. children meet the 60 min.d-1 physical activity (PA) guideline. Structured after-school PA programing is one approach to help increase activity levels. This study aimed to evaluate the feasibility and short-term impact of a supervised after-school PA and nutrition education program on activity levels. Methods Forty-two 3rd-5th graders from an inner-city school in Boston, MA were randomly assigned to a 10-wk after-school program of either: 1) weekly nutrition education, or 2) weekly nutrition education plus supervised PA 3 d.wk-1 at a community-based center. At baseline and follow-up, PA was measured using accelerometry and fitness (VO2max) was estimated using the PACER 15-m shuttle run. Additional measures obtained were non-fasting finger stick total cholesterol (TC) and glucose levels, waist circumference (WC), body mass index (BMI), percent body fat (%BF), and blood pressure (BP). Values are presented as mean±SE, unless noted otherwise. Results Thirty-six participants completed the study (mean±SD; age 9.7±0.9 years). Participants attended >80% of the sessions. After adjusting for accelerometer wear time and other design factors, light and moderate-to-vigorous PA (MVPA) increased in the nutrition+PA group (+21.5±14.5 and +8.6±8.0 min.d-1, respectively) and decreased in the nutrition only group (-35.2±16.3 and -16.0±9.0 min.d-1, respectively); mean difference between groups of 56.8±21.7 min.d-1 (light PA, p = 0.01) and 24.5±12.0 min.d-1 (MVPA, p = 0.04). Time spent in sedentary behaviors declined in the nutrition+PA group (-14.8±20.7 min.d-1) and increased in the nutrition only group (+55.4±23.2 min.d-1); mean difference between groups of -70.2±30.9 min.d-1 (p = 0.02). Neither group showed changes in TC, BP, WC, %BF, BMI percentile, or fitness (p>0.05). Conclusions The supervised afterschool community-based nutrition and PA program was well accepted and had high attendance. The changes in light PA and MVPA has potential

  16. PREFACE: 3rd International Conference on Science & Engineering in Mathematics, Chemistry and Physics 2015 (ScieTech 2015)

    NASA Astrophysics Data System (ADS)

    Gaol, F. L.

    2015-06-01

    The 3rd International Conference on Science & Engineering in Mathematics, Chemistry and Physics 2015 (ScieTech 2015), was held at The Westin Resort Nusa Dua, Bali on 31 January - 1 February 2015. The ScieTech 2015 conference is aimed to bring together researchers, engineers and scientists from around the world. ScieTech 2015 is placed on promoting interaction between the theoretical, experimental, and applied communities, so that a high level exchange is achieved in new and emerging areas within mathematics, chemistry and physics. As we already know that science and technology have brought tremendous benefits for human civilization. People are becoming healthier, wealthier, better educated, more peaceful, increasingly connected, and living longer. Of course, science and technology provide many answers to global challenges, but we will face more complex problems in the next decade due to increasing world population, limitation of energy, and climate change. Therefore, researchers should be more active in conducting research that enables collaboration between one and the others. Interdisciplinary cooperation is absolutely necessary in order to create a smart system for solving the global problems. We need a global and general long-term view of the future with long-range goals for solving complex problems in next decade. Therefore the conference was held to be a forum for researchers from different disciplines to start collaborating and conducting research that provides a solution to the global issues. The theme of ScieTech 2015 was ''The interdisciplinary Application between Mathematics, Chemistry and Physics to enhance the Quality of Life''. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting conference program as well as the invited and plenary speakers. This year, we received 197 papers and after rigorous review, 59 papers were accepted. The participants came from 19

  17. LANL Water Protection Status Report - FY12 3rd Qtr. (Apr thru Jun 2012)

    SciTech Connect

    Douglass, Craig R.

    2012-07-12

    Continued monitoring of the Buckman Direct Diversion and Los Alamos County Water Supply Wells; Groundwater Protection - Continued implementation of the Interim Facility-Wide Groundwater Monitoring Plan (IFGMP); Surface Water Protection - Continued protection of surface water through implementation of the Individual Stormwater Permit (IP); Buckman Early Notification System operability at 100% per MOU Requirements.

  18. FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

    NASA Astrophysics Data System (ADS)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2013-10-01

    Conference logo This volume of Journal of Physics: Conference Series is dedicated to the scientific contributions presented during the 3rd International Workshop on New Computational Methods for Inverse Problems, NCMIP 2013 (http://www.farman.ens-cachan.fr/NCMIP_2013.html). This workshop took place at Ecole Normale Supérieure de Cachan, in Cachan, France, on 22 May 2013, at the initiative of Institut Farman. The prior editions of NCMIP also took place in Cachan, France, firstly within the scope of the ValueTools Conference, in May 2011 (http://www.ncmip.org/2011/), and secondly at the initiative of Institut Farman, in May 2012 (http://www.farman.ens-cachan.fr/NCMIP_2012.html). The NCMIP Workshop focused on recent advances in the resolution of inverse problems. Indeed inverse problems appear in numerous scientific areas such as geophysics, biological and medical imaging, material and structure characterization, electrical, mechanical and civil engineering, and finances. The resolution of inverse problems consists of estimating the parameters of the observed system or structure from data collected by an instrumental sensing or imaging device. Its success firstly requires the collection of relevant observation data. It also requires accurate models describing the physical interactions between the instrumental device and the observed system, as well as the intrinsic properties of the solution itself. Finally, it requires the design of robust, accurate and efficient inversion algorithms. Advanced sensor arrays and imaging devices provide high rate and high volume data; in this context, the efficient resolution of the inverse problem requires the joint development of new models and inversion methods, taking computational and implementation aspects into account. During this one-day workshop, researchers had the opportunity to bring to light and share new techniques and results in the field of inverse problems. The topics of the workshop were: algorithms and computational

  19. PREFACE: 3rd Workshop on Theory, Modelling and Computational Methods for Semiconductors (TMCSIII)

    NASA Astrophysics Data System (ADS)

    Califano, Marco; Migliorato, Max; Probert, Matt

    2012-05-01

    These conference proceedings contain the written papers of the contributions presented at the 3rd International Conference on Theory, Modelling and Computational Methods for Semiconductor materials and nanostructures. The conference was held at the School of Electronic and Electrical Engineering, University of Leeds, Leeds, UK on 18-20 January 2012. The previous conferences in this series took place in 2010 at St William's College, York and in 2008 at the University of Manchester, UK. The development of high-speed computer architectures is finally allowing the routine use of accurate methods for calculating the structural, thermodynamic, vibrational, optical and electronic properties of semiconductors and their hetero- and nano-structures. The scope of this conference embraces modelling, theory and the use of sophisticated computational tools in semiconductor science and technology, where there is substantial potential for time-saving in R&D. Theoretical approaches represented in this meeting included: Density Functional Theory, Tight Binding, Semiempirical Pseudopotential Methods, Effective Mass Models, Empirical Potential Methods and Multiscale Approaches. Topics included, but were not limited to: Optical and Transport Properties of Quantum Nanostructures including Colloids and Nanotubes, Plasmonics, Magnetic Semiconductors, Graphene, Lasers, Photonic Structures, Photovoltaic and Electronic Devices. This workshop ran for three days, with the objective of bringing together UK and international leading experts in the theoretical modelling of Group IV, III-V and II-VI semiconductors, as well as students, postdocs and early-career researchers. The first day focused on providing an introduction and overview of this vast field, aimed particularly at students, with several lectures given by recognised experts in various theoretical approaches. The following two days showcased some of the best theoretical research carried out in the UK in this field, with several

  20. Differences and similarities among volunteers who drop out during the first year and volunteers who continue after eight years.

    PubMed

    Vecina Jiménez, María Luisa; Chacón Fuertes, Fernando; Sueiro Abad, Manuel J

    2010-05-01

    Differences and similarities between 130 volunteers who remain for more than eight years in the same non-profit organization and 110 volunteers who quit during the first year were analyzed in this paper. Both groups were chosen from a sample of 851 volunteers that were working as volunteers when we assessed the independent variables (Time 1). After a 12-month follow-up (Time 2), 209 (25%) of them had dropped out and 642 (75%) continued in the same organization. Using the previous time, we formed two groups made up of those who dropped out and had been in the organization less than a year and those who continued and had been in the organization more than 8 years. Results show that differences and similarities between both groups are coherent with the three-stage model of volunteer's duration (Chacón, Vecina, & Dávila, 2007). This model includes the functional approach of volunteers' motivations (Clary & Snyder, 1991), and the role identity approach (Callero, 1985), and indicates that people will remain as volunteers insofar as this satisfies the motivations that are relevant for them at the first stage, they develop organizational commitment at the second stage, and they develop role identity as volunteers at the third stage. More specifically, results show that it is possible to predict 85% of the cases correctly using seven variables. Volunteers who remain after eight years feel a higher level of emotional exhaustion, a higher level of organizational commitment, and a strong role identity as volunteers. They are also highly satisfied with the friendships in the organization and have a stronger intention to remain at the long-term (2 years).

  1. Life Course and Intergenerational Continuity of Intimate Partner Aggression and Physical Injury: A 20-Year Study.

    PubMed

    Knight, Kelly E; Menard, Scott; Simmons, Sara B; Bouffard, Leana A; Orsi, Rebecca

    2016-01-01

    The objective of this study is to examine continuity of intimate partner aggression (IPA), which is defined as repeated annual involvement in IPA, across respondents' life course and into the next generation, where it may emerge among adult children. A national, longitudinal, and multigenerational sample of 1,401 individuals and their adult children is analyzed. Annual data on IPA severity and physical injury were collected by the National Youth Survey Family Study across a 20-year period from 1984 to 2004. Three hypotheses and biological sex differences are tested and effect sizes are estimated. First, findings reveal evidence for life course continuity (IPA is a strong predictor of subsequent IPA), but the overall trend decreases over time. Second, intergenerational continuity is documented (parents' IPA predicts adult children's IPA), but the effect is stronger for female than for male adult children. Third, results from combined and separate, more restrictive, measures of victimization and perpetration are nearly identical except in the intergenerational analyses. Fourth, evidence for continuity is not found when assessing physical injury alone. Together, these findings imply that some but not all forms of IPA are common, continuous, and intergenerational. Life course continuity appears stronger than intergenerational continuity. PMID:27076093

  2. Efficacy and safety of continuous 4-year telbivudine treatment in patients with chronic hepatitis B

    PubMed Central

    Wang, Y; Thongsawat, S; Gane, E J; Liaw, Y-F; Jia, J; Hou, J; Chan, H L Y; Papatheodoridis, G; Wan, M; Niu, J; Bao, W; Trylesinski, A; Naoumov, N V

    2013-01-01

    In the phase-III GLOBE/015 studies, telbivudine demonstrated superior efficacy vs lamivudine during 2-year treatment in HBeAg-positive and HBeAg-negative chronic hepatitis B (CHB). After completion, 847 patients had an option to continue telbivudine treatment for further 2 years. A total of 596 (70%) of telbivudine-treated patients, who were serum HBV DNA positive or negative and without genotypic resistance to telbivudine at the end of the GLOBE/015 trials, were enrolled into a further 2-year extension study. A group of 502 patients completed 4 years of continuous telbivudine treatment and were included in the telbivudine per-protocol population. Amongst 293 HBeAg-positive patients, 76.2% had undetectable serum HBV DNA and 86.0% had normal serum ALT at the end of 4 years. Notably, the cumulative rate of HBeAg seroconversion was 53.2%. Amongst 209 HBeAg-negative patients, 86.4% had undetectable HBV DNA and 89.6% had normal serum ALT. In patients who had discontinued telbivudine treatment due to HBeAg seroconversion, the HBeAg response was durable in 82% of patients (median 111 weeks of off-treatment follow-up). The cumulative 4-year resistance rate was 10.6% for HBeAg-positive and 10.0% for HBeAg-negative patients. Most adverse events were mild or moderate in severity and transient. Renal function measured by estimated glomerular filtration rate (eGFR) increased by 14.9 mL/min/1.73 m2 (16.6%) from baseline to 4 years (P < 0.0001). In conclusion, in HBeAg-positive and HBeAg-negative CHB patients without resistance after 2 years, two additional years of telbivudine treatment continued to provide effective viral suppression with a favourable safety profile. Moreover, telbivudine achieved 53% of HBeAg seroconversion in HBeAg-positive patients. PMID:23490388

  3. FOREWORD: 3rd International Workshop on New Computational Methods for Inverse Problems (NCMIP 2013)

    NASA Astrophysics Data System (ADS)

    Blanc-Féraud, Laure; Joubert, Pierre-Yves

    2013-10-01

    Conference logo This volume of Journal of Physics: Conference Series is dedicated to the scientific contributions presented during the 3rd International Workshop on New Computational Methods for Inverse Problems, NCMIP 2013 (http://www.farman.ens-cachan.fr/NCMIP_2013.html). This workshop took place at Ecole Normale Supérieure de Cachan, in Cachan, France, on 22 May 2013, at the initiative of Institut Farman. The prior editions of NCMIP also took place in Cachan, France, firstly within the scope of the ValueTools Conference, in May 2011 (http://www.ncmip.org/2011/), and secondly at the initiative of Institut Farman, in May 2012 (http://www.farman.ens-cachan.fr/NCMIP_2012.html). The NCMIP Workshop focused on recent advances in the resolution of inverse problems. Indeed inverse problems appear in numerous scientific areas such as geophysics, biological and medical imaging, material and structure characterization, electrical, mechanical and civil engineering, and finances. The resolution of inverse problems consists of estimating the parameters of the observed system or structure from data collected by an instrumental sensing or imaging device. Its success firstly requires the collection of relevant observation data. It also requires accurate models describing the physical interactions between the instrumental device and the observed system, as well as the intrinsic properties of the solution itself. Finally, it requires the design of robust, accurate and efficient inversion algorithms. Advanced sensor arrays and imaging devices provide high rate and high volume data; in this context, the efficient resolution of the inverse problem requires the joint development of new models and inversion methods, taking computational and implementation aspects into account. During this one-day workshop, researchers had the opportunity to bring to light and share new techniques and results in the field of inverse problems. The topics of the workshop were: algorithms and computational

  4. Tunnelling of the 3rd kind: A test of the effective non-locality of quantum field theory

    NASA Astrophysics Data System (ADS)

    Gardiner, Simon A.; Gies, Holger; Jaeckel, Joerg; Wallace, Chris J.

    2013-03-01

    Integrating out virtual quantum fluctuations in an originally local quantum field theory results in an effective theory which is non-local. In this letter we argue that tunnelling of the 3rd kind —where particles traverse a barrier by splitting into a pair of virtual particles which recombine only after a finite distance— provides a direct test of this non-locality. We sketch a quantum-optical setup to test this effect, and investigate observable effects in a simple toy model.

  5. Three year continuous abstinence in a smoking cessation study using the nicotine transdermal patch.

    PubMed

    Richmond, R L; Kehoe, L; de Almeida Neto, A C

    1997-12-01

    A total of 305 subjects from Sydney were randomly allocated to receive either an active (24 hour transdermal nicotine patch over a 10 week course) or placebo nicotine patch. All subjects participated in a multicomponent cognitive-behavioural smoking cessation programme over five weeks in two-hour group sessions. The continuous abstinence rates at three years (validated by expired carbon monoxide) were 13.8% for the active group and 5.2% for placebo group (p = 0.011). The active nicotine patch with behavioural therapy achieved more than double the abstinence rates early in treatment compared with placebo and this difference was maintained throughout the three year follow up.

  6. Continuous ambulatory peritoneal dialysis: three-year experience at one center.

    PubMed

    Nolph, K D; Sorkin, M; Rubin, J; Arfania, D; Prowant, B; Fruto, L; Kennedy, D

    1980-05-01

    Three years of clinical experience with continuous ambulatory peritoneal dialysis are summarized. Serum urea nitrogen, creatinine, hematocrit, nerve conduction velocity, calcium, inorganic phosphorus, serum proteins, and electrolytes have been maintained in acceptable ranges. Peritonitis, although reduced in incidence because of solutions in plastic bags and a new adapter, is still a problem. Excessive carbohydrate absorption, obesity, and high serum triglyceride concentrations may be long-term problems in some patients. PMID:7387001

  7. Residence Life and the New Student Experience, 3rd Edition. The First-Year Experience Monograph Series No. 5

    ERIC Educational Resources Information Center

    Zeller, William J., Ed.

    2008-01-01

    Residence life programs play a key role in recruiting students, helping them make a successful transition to a new institution, and in retaining them, whether students are enrolling for the first time, transferring from another institution, or entering graduate school. Chapters in this book address theories of learning and development, new…

  8. 42 Years of Continuous Observations of the Solar Diameter - 1974 to 2015

    NASA Astrophysics Data System (ADS)

    Humberto Andrei, Alexandre; Calderari Boscardin, Sergio; Lousada Penna, Jucira; Vani Leister, Nelson

    2015-08-01

    We present an analysis of 42 years of continuous measurements of the photospheric solar diameter, taken at major national observatories, using the same fundamental method, and similar apparatus. Such a series overlap observations from the Calern Observatory/France (Solar Astrolabe in 1975-2003 to 253 obs/year lead by F. Laclare and C. Delmas; Doraysol in 2000-2005 to 3,070 obs/year lead by C. Delmas and V. Sinceac), from the IAG/USP/Brazil (Solar Astrolabe in 1974-1994 to 95 obs/year lead by N. VaniLeister, P. Benevides and M. Emilio), from the Antalya Observatory/Turkey (CCD Astrolabe in 2000-2007 to 400 obs/year lead by F. Chollet and OI. Golbasi), from the San Fernando Observatory/Spain (Solar Astrolabe in 1972-1975 to 133 obs/year lead by J. Muiños), from Observatório Nacional/Brasil (CCD Astrolabe in 1998-2009 to 1,820 obs/year lead by J. Penna, E. Reis Neto and A.H. Andrei; Heliometer 2010-2015 to 8,509 obs/year lead by S.C. Boscardin, J.L. Penna and A.H. Andrei). The Heliometer is fully automatized in its observations and continues in regular operation with no plan of stopping; it shares with the former instruments the physical/mathematical definition of the limb, and the instruments aperture and focal length. We perform a reconciliation of all these series, using the common stretches. A modulation with the 11 years cycle of solar activity is evident. However when such modulation is removed, both from the solar diameter compound series and from the solar activity series (given by the sunspots count), a very strong anti-correlation surfaces. This suggests a smaller diameter for the forthcoming cycles, in a behavior similar to that on the Minima of Dalton and Maunder. This study stresses the importance of keeping and make available such long, continuous, and uniform series of solar diameter measurements. Maybe even the more by the controversy about its magnitude and origin. This presentation is dedicated to all the teams that developed and sustained the

  9. Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: preparation, in vitro and in vivo evaluation.

    PubMed

    He, Zhijian; Schulz, Anita; Wan, Xiaomeng; Seitz, Joshua; Bludau, Herdis; Alakhova, Daria Y; Darr, David B; Perou, Charles M; Jordan, Rainer; Ojima, Iwao; Kabanov, Alexander V; Luxenhofer, Robert

    2015-06-28

    The clinically and commercially successful taxanes, paclitaxel and docetaxel suffer from two major drawbacks, namely their very low aqueous solubility and the risk of developing resistance. Here, we present a method that overcomes both drawbacks in a very simple manner. We formulated 3rd generation taxoids, able to avoid common drug resistance mechanisms with doubly amphiphilic poly(2-oxazoline)s (POx), a safe and highly efficient polymer for the formulation of extremely hydrophobic drugs. We found excellent solubilization of different 3rd generation taxoids irrespective of the drug's chemical structures with essentially quantitative drug loading and final drug to polymer ratios around unity. The small, highly loaded micelles with a hydrodynamic diameter of less than 100nm are excellently suited for parenteral administration. Moreover, a selected formulation with the taxoid SB-T-1214 is about one to two orders of magnitude more active in vitro than paclitaxel in the multidrug resistant breast cancer cell line LCC6-MDR. In contrast, in wild-type LCC6, no difference was observed. Using a q4d×4 dosing regimen, we also found that POx/SB-T-1214 significantly inhibits the growth of LCC6-MDR orthotropic tumors, outperforming commercial paclitaxel drug Taxol and Cremophor EL formulated SB-T-1214.

  10. Youth and Development. Farm House Dialogue (3rd, Ota, Nigeria, February 24-26, 1989).

    ERIC Educational Resources Information Center

    Africa Leadership Forum.

    This document summarizes discussions at an invitational workshop on youth development in Nigeria. Youth were defined as those between 18 and 40 years of age, with those who were between 30 and 40 years old considered to be "mature youth." The following broad issues were discussed: (1) the characteristics of youth, including their idealism and need…

  11. Information Literacy Skills, Grades 7-12. 3rd Edition. Professional Growth Series.

    ERIC Educational Resources Information Center

    Andronik, Catherine M., Comp.

    In the past 10 years there has been a revolution in information technologies, a revolution that has forever changed the way librarians and library media specialists view and teach "library skills". The frightening thing is that 5 or 10 years from now, many of today's most exiting and promising innovations will be completely obsolete, and there is…

  12. Space flight micro-fungi after 27 years storage in water and in continuous culture.

    PubMed

    Volz, P A; Parent, S L

    1998-01-01

    Four species of micro-fungi were selected for study in the National Aeronautics and Space Administration (NASA) Apollo Microbial Ecology Evaluation Device (MEED) mycology experiments. Trichophyton terrestre, Rhodotorula rubra, Saccharomyces cerevisiae and Chaetomium globosum were selected from a series of preflight test fungi for the MEED mycology studies during the 2 years prior to the actual flight (Volz, 1971a, 1972b). Conidia of T. terrestre, ascospores of C. globosum and yeast cells of R. rubra and S. cerevisiae were suspended in sterile distilled water and loaded into wet and dry cuvettes for exposure to specific space flight parameters according to the filters built into the space flight hardware (Volz, 1971b). Living cells were found in the original inocula and phenotype water storage after 27 years. Colony cells were also examined after 27 years of continuous culture. PMID:10093232

  13. Sunphotometric Measurement of Columnar H2O and Aerosol Optical Depth During the 3rd Water Vapor IOP in Fall 2000 at the SGP ARM Site

    NASA Technical Reports Server (NTRS)

    Schmid, B; Eilers, J. A.; McIntosh, D. M.; Longo, K.; Livingston, J. M.; Redemann, J.; Russell, P. B.; Braun, J.; Rocken, C.; Hipskind, R. Stephen (Technical Monitor)

    2001-01-01

    We conducted ground-based measurements with the Ames Airborne Tracking 6-channel Sunphotometer (AATS-6) during the 3rd Water Vapor IOP (WVIOP3), September 18 - October 8, 2000 at the SGP ARM site. For this deployment our primary result was columnar water vapor (CWV) obtained from continuous solar transmittance measurements in the 0.94-micron band. In addition, we simultaneously measured aerosol optical depth (AOD) at 380, 450, 525, 864 and 1020 nm. During the IOP, preliminary results of CWV and AOD were displayed in real-time. The result files were made available to other investigators by noon of the next day. During WVIOP3 those data were shown on the daily intercomparison plots on the IOP web-site. Our preliminary results for CWV fell within the spread of values obtained from other techniques. After conclusion of WVIOP3, AATS-6 was shipped directly to Mauna Loa, Hawaii for post-mission calibration. The updated calibration, a cloud screening technique for AOD, along with other mostly cosmetic changes were applied to the WVIOP3 data set and released as version 0.1. The resulting changes in CWV are small, the changes in AOD and Angstrom parameter are more noticeable. Data version 0.1 was successfully submitted to the ARM External Data Center. In the poster we will show data examples for both CWV and AOD. We will also compare our CWV results with those obtained from a GPS (Global Positioning System) slant path method.

  14. In situ osmotic analyzer for the year-long continuous determination of Fe in hydrothermal systems

    USGS Publications Warehouse

    Chapin, T.P.; Jannasch, H.W.; Johnson, K.S.

    2002-01-01

    A submersible osmotically pumped analyzer (Fe-OsmoAnalyzer) has been adapted for the long-term continuous high resolution monitoring of iron(II) and (III) in deep-sea hydrothermal vents. Ferrozine is used as the colorimetric reagent. The detection limit for our analyzer is 0.1??M for a 0.7cm pathlength with a linear response up to 50??M. The Fe-OsmoAnalyzer uses periodic injections of standards and blanks to self calibrate and can operate unattended for over a year collecting data every 15min. The Fe-OsmoAnalyzer was field tested during a 6 week test deployment at 900m in Monterey Bay and a year-long deployment at 1100m off the coast of Hawaii. A second year-long deployment in a low temperature hydrothermal vent on the Juan de Fuca Ridge provided high resolution continuous monitoring of Fe and was able to distinguish tidally influenced fluctuations in Fe concentrations. ?? 2002 Elsevier Science B.V. All rights reserved.

  15. Earth's Volcanoes and their Eruptions; the 3rd edition of the Smithsonian Institution's Volcanoes of the World

    NASA Astrophysics Data System (ADS)

    Siebert, L.; Simkin, T.; Kimberly, P.

    2010-12-01

    The 3rd edition of the Smithsonian Institution’s Volcanoes of the World incorporates data on the world’s volcanoes and their eruptions compiled since 1968 by the Institution’s Global Volcanism Program (GVP). Published this Fall jointly by the Smithsonian and the University of California Press, it supplements data from the 1994 2nd edition and includes new data on the number of people living in proximity to volcanoes, the dominant rock lithologies at each volcano, Holocene caldera-forming eruptions, and preliminary lists of Pleistocene volcanoes and large-volume Pleistocene eruptions. The 3rd edition contains data on nearly 1550 volcanoes of known or possible Holocene age, including chronologies, characteristics, and magnitudes for >10,400 Holocene eruptions. The standard 20 eruptive characteristics of the IAVCEI volcano catalog series have been modified to include dated vertical edifice collapse events due to magma chamber evacuation following large-volume explosive eruptions or mafic lava effusion, and lateral sector collapse. Data from previous editions of Volcanoes of the World are also supplemented by listings of up to the 5 most dominant lithologies at each volcano, along with data on population living within 5, 10, 30, and 100 km radii of each volcano or volcanic field. Population data indicate that the most populated regions also contain the most frequently active volcanoes. Eruption data document lava and tephra volumes and Volcanic Explosivity Index (VEI) assignments for >7800 eruptions. Interpretation of VRF data has led to documentation of global eruption rates and the power law relationship between magnitude and frequency of volcanic eruptions. Data with volcanic hazards implications include those on fatalities and evacuations and the rate at which eruptions reach their climax. In recognition of the hazards implications of potential resumption of activity at pre-Holocene volcanoes, the 3rd edition includes very preliminary lists of Pleistocene

  16. Project DEEP STEAM 2nd and 3rd quarter reports, April 1-September 30, 1981

    SciTech Connect

    Moreno, J.B.; Aeschliman, D.P.; Clay, R.G.; Lee, D.O.; Marshall, B.W.; Muir, J.F.

    1982-03-01

    The objective of Project DEEP STEAM is to develop the technology required to economically produce heavy oil from deep reservoirs. The tasks included in this project are development of thermally efficient delivery systems and downhole steam-generation systems. During the period April 1-September 30, 1981, activity was completed on the development of a low-pressure-combustion, indirect-contact downhole generator (Rocketdyne), and effort continued on two high-pressure, direct-contact designs (Foster-Miller Associates, Sandia National Laboratories). Field testing of the Sandia design began in the Wilmington Field at Long Beach, California. This was the first test of a high-pressure, direct-contact downhole steam generator in a deep well. Development of a second Sandia design, using pure oxygen as the oxidizer, was initiated. Progress continued on the Min-Stress II packer concept at L'Garde, Inc., and on the extruded metal packer at Foster-Miller. A new insulant test series was begun at the Tacoma test tower. The instrumented bare-string steam injection test in Canada, initiated in cooperation with Husky Oil in the last report period, was successfully completed in early May. A redesigned test program to allow simultaneous testing of several different insulated tubulars is scheduled for October 1981.

  17. Seventy years of continuous encroachment substantially increases 'blue carbon' capacity as mangroves replace intertidal salt marshes.

    PubMed

    Kelleway, Jeffrey J; Saintilan, Neil; Macreadie, Peter I; Skilbeck, Charles G; Zawadzki, Atun; Ralph, Peter J

    2016-03-01

    Shifts in ecosystem structure have been observed over recent decades as woody plants encroach upon grasslands and wetlands globally. The migration of mangrove forests into salt marsh ecosystems is one such shift which could have important implications for global 'blue carbon' stocks. To date, attempts to quantify changes in ecosystem function are essentially constrained to climate-mediated pulses (30 years or less) of encroachment occurring at the thermal limits of mangroves. In this study, we track the continuous, lateral encroachment of mangroves into two south-eastern Australian salt marshes over a period of 70 years and quantify corresponding changes in biomass and belowground C stores. Substantial increases in biomass and belowground C stores have resulted as mangroves replaced salt marsh at both marine and estuarine sites. After 30 years, aboveground biomass was significantly higher than salt marsh, with biomass continuing to increase with mangrove age. Biomass increased at the mesohaline river site by 130 ± 18 Mg biomass km(-2)  yr(-1) (mean ± SE), a 2.5 times higher rate than the marine embayment site (52 ± 10 Mg biomass km(-2) yr(-1) ), suggesting local constraints on biomass production. At both sites, and across all vegetation categories, belowground C considerably outweighed aboveground biomass stocks, with belowground C stocks increasing at up to 230 ± 62 Mg C km(-2) yr(-1) (± SE) as mangrove forests developed. Over the past 70 years, we estimate mangrove encroachment may have already enhanced intertidal biomass by up to 283 097 Mg and belowground C stocks by over 500 000 Mg in the state of New South Wales alone. Under changing climatic conditions and rising sea levels, global blue carbon storage may be enhanced as mangrove encroachment becomes more widespread, thereby countering global warming. PMID:26670941

  18. Seventy years of continuous encroachment substantially increases 'blue carbon' capacity as mangroves replace intertidal salt marshes.

    PubMed

    Kelleway, Jeffrey J; Saintilan, Neil; Macreadie, Peter I; Skilbeck, Charles G; Zawadzki, Atun; Ralph, Peter J

    2016-03-01

    Shifts in ecosystem structure have been observed over recent decades as woody plants encroach upon grasslands and wetlands globally. The migration of mangrove forests into salt marsh ecosystems is one such shift which could have important implications for global 'blue carbon' stocks. To date, attempts to quantify changes in ecosystem function are essentially constrained to climate-mediated pulses (30 years or less) of encroachment occurring at the thermal limits of mangroves. In this study, we track the continuous, lateral encroachment of mangroves into two south-eastern Australian salt marshes over a period of 70 years and quantify corresponding changes in biomass and belowground C stores. Substantial increases in biomass and belowground C stores have resulted as mangroves replaced salt marsh at both marine and estuarine sites. After 30 years, aboveground biomass was significantly higher than salt marsh, with biomass continuing to increase with mangrove age. Biomass increased at the mesohaline river site by 130 ± 18 Mg biomass km(-2)  yr(-1) (mean ± SE), a 2.5 times higher rate than the marine embayment site (52 ± 10 Mg biomass km(-2) yr(-1) ), suggesting local constraints on biomass production. At both sites, and across all vegetation categories, belowground C considerably outweighed aboveground biomass stocks, with belowground C stocks increasing at up to 230 ± 62 Mg C km(-2) yr(-1) (± SE) as mangrove forests developed. Over the past 70 years, we estimate mangrove encroachment may have already enhanced intertidal biomass by up to 283 097 Mg and belowground C stocks by over 500 000 Mg in the state of New South Wales alone. Under changing climatic conditions and rising sea levels, global blue carbon storage may be enhanced as mangrove encroachment becomes more widespread, thereby countering global warming.

  19. "Why me?": Characterological self-blame and continued victimization in the first year of middle school.

    PubMed

    Schacter, Hannah L; White, Samantha J; Chang, Vickie Y; Juvonen, Jaana

    2015-01-01

    This study examines the role of characterological self-blame as a unique risk factor associated with other known risk factors (depression and its behavioral and social correlates) for continued victimization across the 1st year of middle school. Relying on a large, ethnically diverse sample of 1,698 young adolescents (M(age) = 11.57, SD = .39; 55% female), self-report assessments in the fall and spring included perceptions of victim status, depressive symptoms, friendships, aggression, and responses to a hypothetical victimization vignette assessing both appraisals (characterological self-blame) and behavioral reactions (helpless responding). In addition to depression, characterological self-blame emerged as the most consistent unique risk factor for subsequent victimization. Mediation analysis suggested that the continuity of victimization between fall and spring could be partially explained by increases in characterological self-blame and depressive symptoms. In addition, cross-lagged panel analyses indicated reciprocal relations between peer victimization and characterological self-blame, suggesting cyclical processes. The study findings suggest that attribution retraining in the beginning of middle school might help prevent escalating risk for continued peer victimization. PMID:24483145

  20. 3rd Tech DeltaSphere-3000 Laser 3D Scene Digitizer infrared laser scanner hazard analysis.

    SciTech Connect

    Augustoni, Arnold L.

    2005-02-01

    A laser hazard analysis and safety assessment was performed for the 3rd Tech model DeltaSphere-3000{reg_sign} Laser 3D Scene Digitizer, infrared laser scanner model based on the 2000 version of the American National Standard Institute's Standard Z136.1, for the Safe Use of Lasers. The portable scanner system is used in the Robotic Manufacturing Science and Engineering Laboratory (RMSEL). This scanning system had been proposed to be a demonstrator for a new application. The manufacture lists the Nominal Ocular Hazard Distance (NOHD) as less than 2 meters. It was necessary that SNL validate this NOHD prior to its use as a demonstrator involving the general public. A formal laser hazard analysis is presented for the typical mode of operation for the current configuration as well as a possible modified mode and alternative configuration.

  1. Use of 2nd and 3rd Level Correlation Analysis for Studying Degradation in Polycrystalline Thin-Film Solar Cells

    SciTech Connect

    Albin, D. S.; del Cueto, J. A.; Demtsu, S. H.; Bansal, S.

    2011-03-01

    The correlation of stress-induced changes in the performance of laboratory-made CdTe solar cells with various 2nd and 3rd level metrics is discussed. The overall behavior of aggregated data showing how cell efficiency changes as a function of open-circuit voltage (Voc), short-circuit current density (Jsc), and fill factor (FF) is explained using a two-diode, PSpice model in which degradation is simulated by systematically changing model parameters. FF shows the highest correlation with performance during stress, and is subsequently shown to be most affected by shunt resistance, recombination and in some cases voltage-dependent collection. Large decreases in Jsc as well as increasing rates of Voc degradation are related to voltage-dependent collection effects and catastrophic shunting respectively. Large decreases in Voc in the absence of catastrophic shunting are attributed to increased recombination. The relevance of capacitance-derived data correlated with both Voc and FF is discussed.

  2. Innovative Strategies for Enhancing Geoscience: Lesson Plans from the 3rd Millennium B.C.E.

    NASA Astrophysics Data System (ADS)

    Romani, P. N.; Bartholomew, I.; Frank, M.; Hackett, K.; Jackson, T.; Melzer, S.; 6th Grade,

    2002-05-01

    Each year the fifth and sixth grade students at Glenarden Woods Elementary Magnet School for Talented and Gifted (TAG) Students, in Glenarden, Maryland study an ancient culture to provide a unifying theme to their studies. The thematic unit is year-long and involves language arts, social studies, and art. Originally, the curriculum did not include any math or science, but for the past seven years we have been working to integrate the technology of the ancient culture into the program. Our goals are to keep the science as hands on as possible and to have the students learn by solving problems. This year's culture was ancient Egypt and the math and science components had a distinctive geoscience flavor to them. The initial problem for the students was to how to lay out a pyramid so that the four sides were aligned with the four cardinal directions as the pyramids are in Egypt. In keeping with the spirit of their studies they had to do so as the Egyptians did, i.e. without a pole star and without the use of any "modern" conveniences such as compasses, global positioning systems, etc. The problem was solved by measurements and observations of a gnomon's shadow. This work then provided a nice springboard for their next problem, duplicating Eratosthenes's measurement of the circumference of the Earth. Eratosthenes was a Greek who lived and experimented in Egypt in the Ptolemaic era. His determination of the Earth's circumference was within 15% of the modern day value. For this work the students had to team with other elementary students in Amherst, Massachusetts. We will present how we did the projects and lessons learned.

  3. Conference Report on the 3rd International Symposium on Lithium Application for Fusion Devices

    NASA Astrophysics Data System (ADS)

    Mazzitelli, G.; Hirooka, Y.; Hu, J. S.; Mirnov, S. V.; Nygren, R.; Shimada, M.; Ono, M.; Tabares, F. L.

    2015-02-01

    The third International Symposium on Lithium Application for Fusion Device (ISLA-2013) was held on 9-11 October 2013 at ENEA Frascati Centre with growing participation and interest from the community working on more general aspect of liquid metal research for fusion energy development. ISLA-2013 has been confirmed to be the largest and the most important meeting dedicated to liquid metal application for the magnetic fusion research. Overall, 45 presentation plus 5 posters were given, representing 28 institutions from 11 countries. The latest experimental results from nine magnetic fusion devices were presented in 16 presentations from NSTX (PPPL, USA), FTU (ENEA, Italy), T-11M (Trinity, RF), T-10 (Kurchatov Institute, RF), TJ-II (CIEMAT, Spain), EAST(ASIPP, China), HT-7 (ASIPP, China), RFX (Padova, Italy), KTM (NNC RK, Kazakhstan). Sessions were devoted to the following: (I) lithium in magnetic confinement experiments (facility overviews), (II) lithium in magnetic confinement experiments (topical issues), (III) special session on liquid lithium technology, (IV) lithium laboratory test stands, (V) Lithium theory/modelling/comments, (VI) innovative lithium applications and (VII) special Session on lithium-safety and lithium handling. There was a wide participation from the fusion technology communities, including IFMIF and TBM communities providing productive exchange with the physics oriented magnetic confinement liquid metal research groups. This international workshop will continue on a biennial basis (alternating with the Plasma-Surface Interactions (PSI) Conference) and the next workshop will be held at CIEMAT, Madrid, Spain, in 2015.

  4. Conference report on the 3rd International Symposium on Lithium Application for Fusion Devices

    SciTech Connect

    Mazzitelli, Guiseppe; Hirooka, Y.; Hu, J. S.; Mirnov, S. V.; Nygren, R.; Shimada, M.; Ono, M.; Tabares, F. L.

    2015-01-14

    The third International Symposium on Lithium Application for Fusion Device (ISLA-2013) was held on 9-11 October 2013 at ENEA Frascati Centre with growing participation and interest from the community working on more general aspect of liquid metal research for fusion energy development. ISLA-2013 has been confirmed to be the largest and the most important meeting dedicated to liquid metal application for the magnetic fusion research. Overall, 45 presentation plus 5 posters were given, representing 28 institutions from 11 countries. The latest experimental results from nine magnetic fusion devices were presented in 16 presentations from NSTX (PPPL, USA), FTU (ENEA, Italy), T-11M (Trinity, RF), T-10 (Kurchatov Institute, RF), TJ-II (CIEMAT, Spain), EAST(ASIPP, China), HT-7 (ASIPP, China), RFX (Padova, Italy), KTM (NNC RK, Kazakhstan). Sessions were devoted to the following: (I) lithium in magnetic confinement experiments (facility overviews), (II) lithium in magnetic confinement experiments (topical issues), (III) special session on liquid lithium technology, (IV) lithium laboratory test stands, (V) Lithium theory/modelling/comments, (VI) innovative lithium applications and (VII) special Session on lithium-safety and lithium handling. There was a wide participation from the fusion technology communities, including IFMIF and TBM communities providing productive exchange with the physics oriented magnetic confinement liquid metal research groups. Furthermore, this international workshop will continue on a biennial basis (alternating with the Plasma-Surface Interactions (PSI) Conference) and the next workshop will be held at CIEMAT, Madrid, Spain, in 2015.

  5. [From contents to competency. Educational strategies for the physicians of the 3rd millennium].

    PubMed

    Consorti, Fabrizio

    2015-02-01

    Italy, as well as many other countries, is facing the problem to adapt medical education to the challenges of a rapidly changing, globalised world. One main concern is the mismatch of competencies to patient and population needs, which calls for an orientation to a competency-based medical education. Competency is defined as the ability to use knowledge, skills and attitudes in a professional context. Addressing to competency the educational design implies to overcome the boundaries of disciplines to consider mainly the final outcome. A number of international initiatives have defined systems of competency, such as TUNING Medicine or CanMeds, which can form a sound base for the development of a national system. An overall picture of professional competencies allows also to design a continuum between pre- and post-graduate training, up to the continuous professional development. A second essential issue is the adoption of the point of view of complexity in considering the educational system, as well as to focus on reflective thinking as a meta-competency. The National Conference of the Directors of Medical Curricula is running a set of initiatives to support this process of change.

  6. Conference report on the 3rd International Symposium on Lithium Application for Fusion Devices

    DOE PAGES

    Mazzitelli, Guiseppe; Hirooka, Y.; Hu, J. S.; Mirnov, S. V.; Nygren, R.; Shimada, M.; Ono, M.; Tabares, F. L.

    2015-01-14

    The third International Symposium on Lithium Application for Fusion Device (ISLA-2013) was held on 9-11 October 2013 at ENEA Frascati Centre with growing participation and interest from the community working on more general aspect of liquid metal research for fusion energy development. ISLA-2013 has been confirmed to be the largest and the most important meeting dedicated to liquid metal application for the magnetic fusion research. Overall, 45 presentation plus 5 posters were given, representing 28 institutions from 11 countries. The latest experimental results from nine magnetic fusion devices were presented in 16 presentations from NSTX (PPPL, USA), FTU (ENEA, Italy),more » T-11M (Trinity, RF), T-10 (Kurchatov Institute, RF), TJ-II (CIEMAT, Spain), EAST(ASIPP, China), HT-7 (ASIPP, China), RFX (Padova, Italy), KTM (NNC RK, Kazakhstan). Sessions were devoted to the following: (I) lithium in magnetic confinement experiments (facility overviews), (II) lithium in magnetic confinement experiments (topical issues), (III) special session on liquid lithium technology, (IV) lithium laboratory test stands, (V) Lithium theory/modelling/comments, (VI) innovative lithium applications and (VII) special Session on lithium-safety and lithium handling. There was a wide participation from the fusion technology communities, including IFMIF and TBM communities providing productive exchange with the physics oriented magnetic confinement liquid metal research groups. Furthermore, this international workshop will continue on a biennial basis (alternating with the Plasma-Surface Interactions (PSI) Conference) and the next workshop will be held at CIEMAT, Madrid, Spain, in 2015.« less

  7. Definition of yearly emission factor of dust and greenhouse gases through continuous measurements in swine husbandry

    NASA Astrophysics Data System (ADS)

    Costa, Annamaria; Guarino, Marcella

    The object of this study was to develop an accurate estimation method to evaluate the contribution of the various compartments of swine husbandry to dust and GHG (greenhouse gases, CO 2, CH 4 and N 2O) emission into the atmosphere during one year of observation. A weaning, a gestation, a farrowing and a fattening room in an intensive pig house were observed in three different periods (Autumn-Winter, Springtime and Summer, monitoring at least 60% of each period (20% at the beginning, in the middle and at the end) of each cycle). During monitoring, live weight, average live weight gain, number of animals and its variation, type of feed and feeding time were taken into account to evaluate their influence on PM 10, or the fraction of suspended particulate matter with an aerodynamic diameter less than or equal to 10 μm [Emission Inventory Guidebook, 2007. B1100 Particle Emissions from Animal Husbandry Activities. Available from: (accessed October 2008)] and to define GHG emission. The selected piggery had a ventilation control system using a free running impeller to monitor continuously real-time environmental and management parameters with an accuracy of 5%. PM 10 concentration was monitored by a sampler (Haz Dust EPAM 5000), either continuously or through traditional gravimetric technique, and the mean value of dust amount collected on the membranes was utilized as a correction factor to be applied to continuously collected data. PM 10 concentration amount incoming from inlets was removed from PM 10 emission calculation, to estimate the real contribution of pig house dust pollution into atmosphere. Mean yearly emission factor of PM 10 was measured in 2 g d -1 LU -1 for the weaning room, 0.09 g d -1 LU -1 for the farrowing room, 2.59 g d -1 LU -1 for the fattening room and 1.23 g d -1 LU -1 for the gestation room. The highest PM 10 concentration and emission per LU was recorded in the fattening compartment

  8. Quadriceps strength and weight acceptance strategies continue to improve two years after anterior cruciate ligament reconstruction.

    PubMed

    Roewer, Ben D; Di Stasi, Stephanie L; Snyder-Mackler, Lynn

    2011-07-01

    The anterior cruciate ligament (ACL) is the most commonly-injured knee ligament during sporting activities. After injury, most individuals experience episodes of the knee giving way during daily activities (non-copers). Non-copers demonstrate asymmetrical quadriceps strength and movement patterns, which could have long-term deleterious effects on the integrity of the knee joint. The purpose of this study was to determine if non-copers resolve their strength and movement asymmetries within two years after surgery. 26 Non-copers were recruited to undergo pre-operative quadriceps strength testing and 3-dimensional gait analysis. Subjects underwent surgery to reconstruct the ligament followed by physical therapy focused on restoring normal range of motion, quadriceps strength, and function. Subjects returned for quadriceps strength testing and gait analysis six months and two years after surgery. Acutely after injury, quadriceps strength was asymmetric between limbs, but resolved six months after surgery. Asymmetric knee angles, knee moments, and knee and hip power profiles were also observed acutely after injury and persisted six months after surgery despite subjects achieving symmetrical quadriceps strength. Two years after surgery, quadriceps strength in the involved limb continued to improve and most kinematic and kinetic asymmetries resolved. These findings suggest that adequate quadriceps strength does not immediately resolve gait asymmetries in non-copers. They also suggest that non-copers have the capacity to improve their quadriceps strength and gait symmetry long after ACL reconstruction.

  9. ICoVax 2013: the 3rd ISV Pre-conference Computational Vaccinology Workshop.

    PubMed

    De Groot, Anne S; De Groot, Phoebe; He, Yongqun

    2014-01-01

    Following last year's computational vaccinology workshop in Shanghai, China, the third ISV Pre-conference Computational Vaccinology Workshop (ICoVax 2013) was held in Barcelona, Spain. ICoVax 2013 provided an international platform for the attendees to showcase their research and discuss problems and solutions in the development and application of computational vaccinology and vaccine informatics tools. The first of the three full-length papers presented at ICoVax discussed the discovery of viral "camouflage" through cross-conservation of T-cell epitopes using a tool called JanusMatrix. This important paper reports that viruses may camouflage their presence in the human body by incorporating sequences in their proteins that are highly cross-conserved at the T-cell receptor surface with human genome proteins, a discovery that has wide ranging implications for the development of vaccines against viruses that use the camouflage method. The other papers described a database for storing experimentally verified data on DNA vaccines and compared therapeutic targets of western drugs to Chinese herbal medicines for cardiovascular diseases. The short poster presentations covered various uses of informatics tools for processing the DNA and microRNA of pathogens to improve vaccine coverage, efficacy and development. A live (on-line) demonstration of the vaccine design toolkit, iVax, presented by Frances Terry of EpiVax, illustrated how computational vaccinology could be used in the design of next generation vaccines.

  10. Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years

    PubMed Central

    Mushegyan, Vagan; Eronen, Jussi T.; Lawing, A. Michelle; Sharir, Amnon; Janis, Christine; Jernvall, Jukka; Klein, Ophir D.

    2015-01-01

    Summary The fossil record is widely informative about evolution, but fossils are not systematically used to study the evolution of stem cell-driven renewal. Here, we examined evolution of the continuous growth (hypselodonty) of rodent molar teeth, which is fuelled by the presence of dental stem cells. We studied occurrences of 3500 North American rodent fossils, ranging from 50 million years ago (mya) to 2 mya. We examined changes in molar height to determine if evolution of hypselodonty shows distinct patterns in the fossil record, and we found that hypselodont taxa emerged through intermediate forms of increasing crown height. Next, we designed a Markov simulation model, which replicated molar height increases throughout the Cenozoic, and, moreover, evolution of hypselodonty. Thus, by extension, the retention of the adult stem-cell niche appears to be a predictable quantitative rather than a stochastic qualitative process. Our analyses predict that hypselodonty will eventually become the dominant phenotype. PMID:25921530

  11. Ablation for atrial fibrillation during mitral valve surgery: 1-year results through continuous subcutaneous monitoring.

    PubMed

    Bogachev-Prokophiev, Alexandr; Zheleznev, Sergey; Romanov, Alexander; Pokushalov, Evgeny; Pivkin, Alexey; Corbucci, Giorgio; Karaskov, Alexander

    2012-07-01

    Continuous monitoring of cardiac rhythm may play an important role in measuring the true symptomatic/asymptomatic atrial fibrillation (AF) burden and improve the management of anti-arrhythmic and anti-thrombotic therapies. Forty-seven patients with mitral valve disease and longstanding persistent AF (LSPAF) underwent a left atrial maze procedure with bipolar radiofrequency and valve surgery. The follow-up data recorded by an implanted loop recorder were analysed after 3, 6 and 12 months. On discharge, 40 (85.1%) patients were in stable sinus rhythm, as documented by in-office electrocardiography (ECG), 4 (8.5%) were in pacemaker rhythm and 3 (6.4%) were in AF. One (2.1%) patient died after 7 months. On 12-month follow-up examination, 30 (65.2%) patients had an AF burden <0.5% and were classified as responders. Three (6.5%) of the 16 non-responders had atrial flutter and 13 (27.7%) had documented AF recurrences with an AF burden >0.5%. Two (4.3%) patients with AF recurrences were completely asymptomatic. Among the symptomatic events stored by the patients, only 27.6% was confirmed as genuine AF recurrences according to the concomitant ECG recorded by the implanted loop recorder. A concomitant bipolar maze procedure during mitral valve surgery is effective in treating AF, as proved by detailed 1-year continuous monitoring. PMID:22514258

  12. Three Thousand Years of Continuity in the Maternal Lineages of Ancient Sheep (Ovis aries) in Estonia

    PubMed Central

    Rannamäe, Eve; Lõugas, Lembi; Speller, Camilla F.; Valk, Heiki; Maldre, Liina; Wilczyński, Jarosław; Mikhailov, Aleksandr; Saarma, Urmas

    2016-01-01

    Although sheep (Ovis aries) have been one of the most exploited domestic animals in Estonia since the Late Bronze Age, relatively little is known about their genetic history. Here, we explore temporal changes in Estonian sheep populations and their mitochondrial genetic diversity over the last 3000 years. We target a 558 base pair fragment of the mitochondrial hypervariable region in 115 ancient sheep from 71 sites in Estonia (c. 1200 BC–AD 1900s), 19 ancient samples from Latvia, Russia, Poland and Greece (6800 BC–AD 1700), as well as 44 samples of modern Kihnu native sheep breed. Our analyses revealed: (1) 49 mitochondrial haplotypes, associated with sheep haplogroups A and B; (2) high haplotype diversity in Estonian ancient sheep; (3) continuity in mtDNA haplotypes through time; (4) possible population expansion during the first centuries of the Middle Ages (associated with the establishment of the new power regime related to 13th century crusades); (5) significant difference in genetic diversity between ancient populations and modern native sheep, in agreement with the beginning of large-scale breeding in the 19th century and population decline in local sheep. Overall, our results suggest that in spite of the observed fluctuations in ancient sheep populations, and changes in the natural and historical conditions, the utilisation of local sheep has been constant in the territory of Estonia, displaying matrilineal continuity from the Middle Bronze Age through the Modern Period, and into modern native sheep. PMID:27732668

  13. Surveillance of Infectious Diseases by the Sentinel Laboratory Network in Belgium: 30 Years of Continuous Improvement.

    PubMed

    Muyldermans, Gaëtan; Ducoffre, Geneviève; Leroy, Mathias; Dupont, Yves; Quolin, Sophie

    2016-01-01

    In 1983 the sentinel laboratory network was established because of the need to describe the epidemiological evolution of infectious diseases. During the study period of 30 years (1983-2013), microbiology laboratories reported on weekly basis the laboratory diagnosed cases for a selection of infectious diseases. This resulted in a large longitudinal laboratory based database allowing to provide trends over time and distribution by person and place. During this period, adaptations to data collection were made due to changes in diagnostic methods and public health priorities, introduction and application of digital revolution, and multiple reorganizations of the laboratories. Since the surveillance network is dynamic, it necessitates a continuous evaluation to ensure that, over time, it continues to be representative of the general epidemiological trends in the country. Secondly the aim is to examine the robustness and stability of this surveillance system. Here we demonstrated that the flexibility of the data collection methodology by the sentinel laboratory network is unique and that adaptations do not affect the capacity of the system to follow trends. Therefore, the surveillance by this network is representative of the current epidemiological situation in Belgium. To our knowledge, no such surveillance network with such a long-term follow-up and demonstrated stability for multiple infectious diseases in the general population was earlier described. Furthermore, expected trends due to the implementation of vaccination or other events were accurately detected. The collected data obtained from this network allows interesting comparisons with other national and international information sources. PMID:27571203

  14. Surveillance of Infectious Diseases by the Sentinel Laboratory Network in Belgium: 30 Years of Continuous Improvement

    PubMed Central

    Muyldermans, Gaëtan; Ducoffre, Geneviève; Leroy, Mathias; Dupont, Yves; Quolin, Sophie

    2016-01-01

    In 1983 the sentinel laboratory network was established because of the need to describe the epidemiological evolution of infectious diseases. During the study period of 30 years (1983–2013), microbiology laboratories reported on weekly basis the laboratory diagnosed cases for a selection of infectious diseases. This resulted in a large longitudinal laboratory based database allowing to provide trends over time and distribution by person and place. During this period, adaptations to data collection were made due to changes in diagnostic methods and public health priorities, introduction and application of digital revolution, and multiple reorganizations of the laboratories. Since the surveillance network is dynamic, it necessitates a continuous evaluation to ensure that, over time, it continues to be representative of the general epidemiological trends in the country. Secondly the aim is to examine the robustness and stability of this surveillance system. Here we demonstrated that the flexibility of the data collection methodology by the sentinel laboratory network is unique and that adaptations do not affect the capacity of the system to follow trends. Therefore, the surveillance by this network is representative of the current epidemiological situation in Belgium. To our knowledge, no such surveillance network with such a long-term follow-up and demonstrated stability for multiple infectious diseases in the general population was earlier described. Furthermore, expected trends due to the implementation of vaccination or other events were accurately detected. The collected data obtained from this network allows interesting comparisons with other national and international information sources. PMID:27571203

  15. PREFACE: 3rd Italian-Pakistani Workshop on Relativistic Astrophysics (IPWRA2011)

    NASA Astrophysics Data System (ADS)

    De Paolis, Francesco; Siddiqui, Azad A.

    2012-03-01

    The Third Italian-Pakistani Workshop on Relativistic Astrophysics was held at the Rectorate of the University of Salento in Lecce on June 20-22, 2011. It follows the first two editions of this Workshop held at the Department of Physics of the University of Salento on 20-22 June 2007 and at ICRA (International Center for Relativistic Astrophysics) in Pescara on 8-10 July 2009. The Proceedings of the first two editions of this Workshop have been published in two special issues of Nuovo Cimento B [1] and General Relativity and Gravitation [2], respectively. The workshop series, whose aim is that of discussing the different aspects (both theoretical and observational) of Relativistic Astrophysics, follows the signature, in 2006, of an agreement between the University of Salento, Italy and the National University of Sciences and Technology (NUST), Pakistan, and aims at promoting scientific and academic cooperation between the parties. The organizing committee of this Workshop has decided to dedicate the present workshop's edition to the celebration of the 65th birthday of the founder of this series of meetings, Prof. Asghar Qadir, one of the greatest Pakistani scientists of any time and a renowned world expert in the theory of general relativity. Many of the Workshop's participants have either been students or collaborators of Asghar Qadir, or both. In Pakistan the words Relativity and Asghar Qadir are synonymous. It would not be entirely wrong to say that anybody who has anything to do with relativity in Pakistan is either his student or a student of one of his students. Asghar Qadir has inspired generations of researchers and teachers, and continues to be a source of inspiration for hard work and dedication. He is a mentor of Pakistani scientists and the equivalent in Pakistan of what John Archibald Wheeler has been in the US. Qadir and Wheeler An autographed picture of John Archibald Wheeler with a young Asghar Qadir Asghar had the rare privilege of being introduced

  16. FOREWORD: 3rd Symposium on Large TPCs for Low Energy Event Detection

    NASA Astrophysics Data System (ADS)

    Irastorza, Igor G.; Colas, Paul; Gorodetzky, Phillippe

    2007-05-01

    The Third International Symposium on large TPCs for low-energy rare-event detection was held at Carré des sciences, Poincaré auditorium, 25 rue de la Montagne Ste Geneviève in Paris on 11 12 December 2006. This prestigious location belonging to the Ministry of Research is hosted in the former Ecole Polytechnique. The meeting, held in Paris every two years, gathers a significant community of physicists involved in rare event detection. Its purpose is an extensive discussion of present and future projects using large TPCs for low energy, low background detection of rare events (low-energy neutrinos, dark matter, solar axions). The use of a new generation of Micro-Pattern Gaseous Detectors (MPGD) appears to be a promising way to reach this goal. The program this year was enriched by a new session devoted to the detection challenge of polarized gamma rays, relevant novel experimental techniques and the impact on particle physics, astrophysics and astronomy. A very particular feature of this conference is the large variety of talks ranging from purely theoretical to purely experimental subjects including novel technological aspects. This allows discussion and exchange of useful information and new ideas that are emerging to address particle physics experimental challenges. The scientific highlights at the Symposium came on many fronts: Status of low-energy neutrino physics and double-beta decay New ideas on double-beta decay experiments Gamma ray polarization measurement combining high-precision TPCs with MPGD read-out Dark Matter challenges in both axion and WIMP search with new emerging ideas for detection improvements Progress in gaseous and liquid TPCs for rare event detection Georges Charpak opened the meeting with a talk on gaseous detectors for applications in the bio-medical field. He also underlined the importance of new MPGD detectors for both physics and applications. There were about 100 registered participants at the symposium. The successful

  17. Six Years Into Its Mission, NASA's Chandra X-ray Observatory Continues to Achieve Scientific Firsts

    NASA Astrophysics Data System (ADS)

    2005-08-01

    In August 1999, NASA's Chandra X-ray Observatory opened for business. Six years later, it continues to achieve scientific firsts. "When Chandra opened its sunshade doors for the first time, it opened the possibility of studying the X-ray emission of the universe with unprecedented clarity," said Chandra project scientist Dr. Martin Weisskopf of NASA's Marshall Space Flight Center in Huntsville, Ala. "Already surpassing its goal of a five-year life, Chandra continues to rewrite textbooks with discoveries about our own solar system and images of celestial objects as far as billions of light years away." Based on the observatory's outstanding results, NASA Headquarters in Washington decided in 2001 to extend Chandra s mission from five years to ten. During the observatory s sixth year of operation, auroras from Jupiter, X-rays from Saturn, and the early days of our solar system were the focus of Chandra discoveries close to home -- discoveries with the potential to better understand the dynamics of life on Earth. Jupiter's auroras are the most spectacular and active auroras in the solar system. Extended Chandra observations revealed that Jupiter s auroral X-rays are caused by highly charged particles crashing into the atmosphere above Jupiter's poles. These results gave scientists information needed to compare Jupiter's auroras with those from Earth, and determine if they are triggered by different cosmic and planetary events. Mysterious X-rays from Saturn also received attention, as Chandra completed the first observation of a solar X-ray flare reflected from Saturn's low-latitudes, the region that correlates to Earth's equator and tropics. This observation led scientists to conclude the ringed planet may act as a mirror, reflecting explosive activity from the sun. Solar-storm watchers on Earth might see a surprising benefit. The results imply scientists could use giant planets like Saturn as remote-sensing tools to help monitor X-ray flaring on portions of the sun

  18. Evidence of human-induced morphodynamic changes along the Campania coastal areas (southern Italy) since the 3rd-4th cent. AD

    NASA Astrophysics Data System (ADS)

    Russo Ermolli, Elda; Romano, Paola; Liuzza, Viviana; Amato, Vincenzo; Ruello, Maria Rosaria; Di Donato, Valentino

    2014-05-01

    Campania has always offered suitable climatic and physiographic conditions for human settlements since prehistoric times. In particular, many Graeco-Roman towns developed along its coasts starting from the 7th-6th cent. BC. In the last decade, geoarchaelogical surveys have been carried out in the archaeological excavations of Neapolis, Paestum and Elea-Velia allowing the main steps of the landscape evolution around these towns to be defined in detail. The greek town of Neapolis rose in the late 6th cent. BC [1] on a terrace overlooking a low-relief rocky coast surrounded by volcanic hills. Port activities developed in a protected bay facing the town from the 4th-2nd cent. BC up to the 4th cent. AD, as testified by the discovery of structures and shipwrecks [2, 3, 4]. Starting from the 3rd cent. AD a spit bar formed at the bay entrance causing the progressive establishment of a lagoon which was gradually filled up by alluvial inputs and completely closed in the 5th cent. AD. During the same period, episodes of increased alluvial inputs were also recorded further west along the coast, where a narrow sandy beach formed at the cliff toe. The greek town of Poseidonia, renamed Paestum by the Romans, was founded in the 540 BC on a travertine terrace facing the sandy littoral of a prograding coastal plain [5]. In front of the main town door, a coastal lagoon developed thanks to the growth of a dune ridge and was probably used for harbor activities [5]. After this period the shoreline shifted seawards, another dune ridge formed and the back-ridge depression was filled with fluvial-marshy deposits, slowly drying up. Phases of travertine deposition, which characterized the SE sector of the plain all along the Holocene, were recorded in the northern and southern quarters of the town in historical times and were connected to the abandonment of the town in the early Medieval times. The greek colony of Elea-Velia was located on top of a siliciclastic promontory where the ruins of

  19. The TOMPs ambient air monitoring network - Continuous data on UK air quality for over 20 years.

    PubMed

    Graf, Carola; Katsoyiannis, Athanasios; Jones, Kevin C; Sweetman, Andrew J

    2016-10-01

    Long-term air monitoring datasets are needed for persistent organic pollutants (POPs) to assess the effectiveness of source abatement measures and the factors controlling ambient levels. The Toxic Organic Micro Pollutants (TOMPs) Network, which has operated since 1991, collects ambient air samples at six sites across England and Scotland, using high-volume active air samplers. The network provides long-term ambient air trend data for a range of POPs at both urban and rural locations. Data from the network provides the UK Government, regulators and researchers with valuable information on emission/source controls and on the effectiveness of international chemicals regulation such as the Stockholm Convention and UN/ECE Protocol on POPs. The target chemicals of TOMPs have been polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and, since 2010, polybrominated diphenyl ethers (PBDEs). The continuous monitoring of these compounds demonstrates the constant decline in UK air concentrations over the last two decades, with average clearance rates for PCDD/Fs in urban locations of 5.1 years and for PCBs across all sites 6.6 years. No significant declines in rural locations for PCDD/Fs have been observed. There is a strong observable link between the declining ambient air concentrations and the emission reductions estimated in the annually produced National Atmospheric Emission Inventory (NAEI) dataset. These findings clearly demonstrate the unique strengths of long-term consistent datasets for the evaluation of the success of chemical regulation and control.

  20. Improving the TNM classification: findings from a 10-year continuous literature review.

    PubMed

    Webber, Colleen; Gospodarowicz, Mary; Sobin, Leslie H; Wittekind, Christian; Greene, Frederick L; Mason, Malcolm D; Compton, Carolyn; Brierley, James; Groome, Patti A

    2014-07-15

    The Union for International Cancer Control's (UICC) TNM classification is a globally accepted system to describe the anatomic extent of malignant tumors. Since its development seventy years ago, the TNM classification has undergone significant revisions to reflect the current understanding of extent of disease and its role in prognosis. To ensure that revisions are evidence-based, the UICC implemented a process for continuous improvement of the TNM classification that included a formalized system for submitting proposals for revisions directly to the UICC and an annual review of the scientific literature on staging that assessed, criticized or made suggestions for changes. The process involves review of the proposals and literature by a group of international, multidisciplinary Expert Panels. The process has been in place for 10 years and informed the development of the 7th edition of the TNM classification published in 2009. The purpose of this article is to provide a description of the annual literature review process, including the search strategy, article selection process and the roles and requirements of the Expert Panels in the review of the literature. Since 2002, 147 Expert Panel members in 11 cancer sites have reviewed over 770 articles. The results of the annual literature reviews, Expert Panel feedback and documentation and dissemination of results are described.

  1. Pulsed Light Accelerated Crosslinking versus Continuous Light Accelerated Crosslinking: One-Year Results

    PubMed Central

    Mazzotta, Cosimo; Traversi, Claudio; Paradiso, Anna Lucia; Latronico, Maria Eugenia

    2014-01-01

    Purpose. To compare functional results in two cohorts of patients undergoing epithelium-off pulsed (pl-ACXL) and continuous light accelerated corneal collagen crosslinking (cl-ACXL) with dextran-free riboflavin solution and high-fluence ultraviolet A irradiation. Design. It is a prospective, comparative, and interventional clinical study. Methods. 20 patients affected by progressive keratoconus were enrolled in the study. 10 eyes of 10 patients underwent an epithelium-off pl-ACXL by the KXL UV-A source (Avedro Inc., Waltham, MS, USA) with 8 minutes (1 sec. on/1 sec. off) of UV-A exposure at 30 mW/cm2 and energy dose of 7.2 J/cm2; 10 eyes of 10 patients underwent an epithelium-off cl-ACXL at 30 mW/cm2 for 4 minutes. Riboflavin 0.1% dextran-free solution was used for a 10-minutes corneal soaking. Patients underwent clinical examination of uncorrected distance visual acuity and corrected distance visual acuity (UDVA and CDVA), corneal topography and aberrometry (CSO EyeTop, Florence, Italy), corneal OCT optical pachymetry (Cirrus OCT, Zeiss Meditec, Jena, Germany), endothelial cells count (I-Conan Non Co Robot), and in vivo scanning laser confocal microscopy (Heidelberg, Germany) at 1, 3, 6, and 12 months of follow-up. Results. Functional results one year after cl-ACXL and pl-ACXL demonstrated keratoconus stability in both groups. Functional outcomes were found to be better in epithelium-off pulsed light accelerated treatment together with showing a deeper stromal penetration. No endothelial damage was recorded during the follow-up in both groups. Conclusions. The study confirmed that oxygen represents the main driver of collagen crosslinking reaction. Pulsed light treatment optimized intraoperative oxygen availability improving postoperative functional outcomes compared with continuous light treatment. PMID:25165576

  2. Effects of continuous and intermittent exercise on executive function in children aged 8-10 years.

    PubMed

    Lambrick, Danielle; Stoner, Lee; Grigg, Rebecca; Faulkner, James

    2016-09-01

    Understanding the effects of acute exercise on executive function in prepubescent children may be important for the enhancement of school performance. This study assessed the effect of an acute bout of continuous (CONT) or intermittent (INT), moderate-intensity treadmill exercise on executive function in young children. Twenty healthy children, mean (SD); age: 8.8 (0.8) years; height: 140 (9) cm; weight: 36 (11) kg; boys: n = 9, performed a graded-exercise test to determine maximal oxygen uptake, and two 15-min submaximal bouts of treadmill exercise; protocols were either CONT or INT. During CONT, participants ran at 90% of gas exchange threshold. During INT, participants performed six consecutive 2.5 min blocks of exercise, which were designed to reflect children's typical activity patterns, comprising 45 s at a heavy intensity, 33 s at a moderate intensity, 10 s at a severe intensity, and 62 s at a low intensity. Participants performed the Stroop task before the submaximal exercise bouts and after, at 1-, 15-, and 30-min intervals. Near-infrared spectroscopy (NIRS) measured cerebral perfusion and oxygenation. Regardless of condition, Stroop performance was improved at 1 min after compared to before, 54.9 (9.8) s versus 57.9 (11) s, respectively, p < .01, and improvements were maintained until 30 min after. NIRS (oxyhemoglobin, total hemoglobin) explained a significant amount of variance in the change in Stroop performance for INT only (49%, p < .05). An acute bout of exercise, of either an intermittent or continuous nature, improves executive function in children, and effects are maintained for ≤ 30 min following exercise cessation. Accordingly, it is recommended that children should engage in physical activity during periods of school recess. PMID:27314635

  3. Organizational Support for the 3rd Summer Institute on Complex Plasmas, July 30 – August 8, 2012

    SciTech Connect

    Lopez, Jose L.

    2012-07-01

    This grant provided partial funds for American graduate students to attend the 3rd Graduate Summer Institute on Complex Plasmas, which was held from July 30 to August 8, 2012 at Seton Hall University in South Orange, New Jersey. The Graduate Summer Institute is a topical series of instructional workshops held bi-annually on the emerging field of complex plasmas that is jointly organized through a collaboration between American and German-European Union plasmas researchers. This specialized program brings together many of the world's leading researchers in the specialized area of complex plasmas, who freely provide instructional lectures and tutorials on the most recent research and discoveries done in this branch of plasma science. The partial funds provided by this grant helped support the travel and accommodation expenses of the participating American students and tutorial instructors. Partial funds further supported the travel and accommodation of three renown American plasma researchers that provided educational tutorials to the thirty-eight participating students from the United States, Europe, and Asia. The organized program afforded a unique opportunity for the participating American graduate students to learn about and engage more deeply in an area of plasma science that is not studied in any of the graduate educational curriculums provided by universities in the United States of America. The educational experience offered by this program provided the necessary knowledge needed by future American plasma researchers to keep the national plasma research effort on the cutting-edge and keep the national plasma community as a global leader.

  4. Development of Partially-Coherent Wavefront Propagation Simulation Methods for 3rd and 4th Generation Synchrotron Radiation Sources.

    SciTech Connect

    Chubar O.; Berman, L; Chu, Y.S.; Fluerasu, A.; Hulbert, S.; Idir, M.; Kaznatcheev, K.; Shapiro, D.; Baltser, J.

    2012-04-04

    Partially-coherent wavefront propagation calculations have proven to be feasible and very beneficial in the design of beamlines for 3rd and 4th generation Synchrotron Radiation (SR) sources. These types of calculations use the framework of classical electrodynamics for the description, on the same accuracy level, of the emission by relativistic electrons moving in magnetic fields of accelerators, and the propagation of the emitted radiation wavefronts through beamline optical elements. This enables accurate prediction of performance characteristics for beamlines exploiting high SR brightness and/or high spectral flux. Detailed analysis of radiation degree of coherence, offered by the partially-coherent wavefront propagation method, is of paramount importance for modern storage-ring based SR sources, which, thanks to extremely small sub-nanometer-level electron beam emittances, produce substantial portions of coherent flux in X-ray spectral range. We describe the general approach to partially-coherent SR wavefront propagation simulations and present examples of such simulations performed using 'Synchrotron Radiation Workshop' (SRW) code for the parameters of hard X-ray undulator based beamlines at the National Synchrotron Light Source II (NSLS-II), Brookhaven National Laboratory. These examples illustrate general characteristics of partially-coherent undulator radiation beams in low-emittance SR sources, and demonstrate advantages of applying high-accuracy physical-optics simulations to the optimization and performance prediction of X-ray optical beamlines in these new sources.

  5. Effects of using relaxation breathing training to reduce music performance anxiety in 3rd to 6th graders.

    PubMed

    Su, Yu-Huei; Luh, Jer-Junn; Chen, Hsin-I; Lin, Chao-Chen; Liao, Miin-Jiun; Chen, Heng-Shuen

    2010-06-01

    The current study examined the effects of applying relaxation breathing training (RBT) as a means to reduce music performance anxiety (MPA) in young, talented musicians. A group of 59 young musicians from 3rd to 6th grade participated in this study, and all of them started RBT twice a week for 2 months prior to the examination. Four tests--2 mos, 1 mos, half an hour and 5 min before the examination--were conducted to examine the level of MPA after the application of RBT. Results show that the degree of MPA 5 min before the trial was lower than the degree of performance anxiety half an hour before the jury (t = -3.683, p < 0.01), which indicated that the RBT was associated with a decrease in MPA. Although a series of RBT exercises was applied, results indicated that when approaching the date of examination, the degree of performance anxiety still increased and reached its maximum half an hour before the jury. The recommendation for future studies is to combine the application of RBT with other methods to expand its effect in reducing MPA.

  6. Changing motor patterns of the 3rd axillary muscle activities associated with longitudinal control in freely flying hawkmoths.

    PubMed

    Ando, Noriyasu; Kanzaki, Ryohei

    2004-02-01

    The 3rd axillary muscles (3AXMs) in the mesothorax in hawkmoths are direct flight muscles and pull forewings back along to the body axis. The 3AXMs are regarded as steering muscles because of their changeable activities during turning flight under tethered conditions. We investigated activities of the upper unit of the 3AXMs during free flight with a micro-telemetry device and captured body and wing movements by high-speed cameras. The 3AXM was activated with 1 to 3 spikes per each wingbeat cycle but sometimes ceased to fire. The phase of the onset of the activities was, even though it was variable, close to the phase of the elevator muscle activities. Therefore the upper unit of the 3AXM activities would affect upstroke properties phasically including wing retractions. We focused on longitudinal flight control and identified a correlation between the phase of the 3AXM and body pitch angle, which is important kinematical parameter for longitudinal control in insect flight. The phasic changes of the 3AXM activities would support quick changes in longitudinal control. PMID:14993822

  7. InAs/GaSb type II superlattices for advanced 2nd and 3rd generation detectors

    NASA Astrophysics Data System (ADS)

    Walther, Martin; Rehm, Robert; Schmitz, Johannes; Fleissner, Joachim; Rutz, Frank; Kirste, Lutz; Scheibner, Ralf; Wendler, Joachim; Ziegler, Johann

    2010-01-01

    InAs/GaSb short-period superlattices (SL) based on GaSb, InAs and AlSb have proven their great potential for high performance infrared detectors. Lots of interest is currently focused on the development of short-period InAs/GaSb SLs for advanced 2nd and 3rd generation infrared detectors between 3 - 30 μm. For the fabrication of mono- and bispectral thermal imaging systems in the mid-wavelength infrared region (MWIR) a manufacturable technology for high responsivity thermal imaging systems has been developed. InAs/GaSb short-period superlattices can be fabricated with up to 1000 periods in the intrinsic region without revealing diffusion limited behavior. This enables the fabrication of InAs/GaSb SL camera systems with high responsivity comparable to state of the art CdHgTe and InSb detectors. The material system is also ideally suited for the fabrication of dual-color MWIR/MWIR InAs/GaSb SL camera systems with high quantum efficiency for missile approach warning systems with simultaneous and spatially coincident detection in both spectral channels.

  8. Altered differential hemocyte count in 3rd instar larvae of Drosophila melanogaster as a response to chronic exposure of Acephate

    PubMed Central

    Rajak, Prem; Dutta, Moumita

    2015-01-01

    Acephate, an organophosphate (OP) pesticide, was used to investigate the effects of its chronic exposure on hemocyte abundance in a non-target dipteran insect Drosophila melanogaster. For this purpose, six graded concentrations ranging from 1 to 6 μg/ml were selected, which are below the reported residual values (up to 14 μg/ml) of the chemical. 1st instar larvae were fed with these concentrations up to the 3rd instar stage and accordingly hemolymph smears from these larvae were prepared for differential hemocyte count. Three types of cells are found in Drosophila hemolymph, namely, plasmatocytes, lamellocytes and crystal cells. Plasmatocyte count was found to decrease with successive increase in treatment concentrations. Crystal cells showed an increasing trend in their number. Though the number of lamellocytes was very low, a bimodal response was noticed. Lamellocyte number was found to increase with the initial three concentrations, followed by a dose dependent reduction in their number. As hemocytes are directly linked to the immune system of fruit flies, fluctuations in normal titer of these cells may affect insect immunity. Hemocytes share homologies in their origin and mode of action with the immune cells of higher organisms including man. Thus the present findings suggest that immune cells of humans and other organisms may be affected adversely under chronic exposure to Acephate. PMID:27486365

  9. TORUS: Theory of Reactions for Unstable iSotopes - Year 1 Continuation and Progress Report

    SciTech Connect

    Arbanas, G; Elster, C; Escher, J; Mukhamedzhanov, A; Nunes, F; Thompson, I J

    2011-02-24

    The TORUS collaboration derives its name from the research it focuses on, namely the Theory of Reactions for Unstable iSotopes. It is a Topical Collaboration in Nuclear Theory, and funded by the Nuclear Theory Division of the Office of Nuclear Physics in the Office of Science of the Department of Energy. The funding started on June 1, 2010, it will have been running for nine months by the date of submission of this Annual Continuation and Progress Report on March 1, 2011. The extent of funding was reduced from the original application, and now supports one postdoctoral researcher for the years 1 through 3. The collaboration brings together as Principal Investigators a large fraction of the nuclear reaction theorists currently active within the USA. The mission of the TORUS Topical Collaboration is to develop new methods that will advance nuclear reaction theory for unstable isotopes by using three-body techniques to improve direct-reaction calculations, and, by using a new partial-fusion theory, to integrate descriptions of direct and compound-nucleus reactions. This multi-institution collaborative effort is directly relevant to three areas of interest: the properties of nuclei far from stability; microscopic studies of nuclear input parameters for astrophysics, and microscopic nuclear reaction theory.

  10. Arrhenius and current climate concerns: Continuity or a 100-year gap?

    NASA Astrophysics Data System (ADS)

    Fleming, James Rodger

    In a paper presented to the Stockholm Physical Society in 1895 and published the following year, Svante Arrhenius demonstrated that variations of atmospheric CO2 concentration could have a very great effect on the overall heat budget and surface temperature of the planet. It would be a mistake, however, to consider this work as a direct forerunner of current climate concerns [Uppenbrink, 1996].Arrhenius, who has recently gained renewed attention as the “father” of the theory of the greenhouse effect, held assumptions and produced results that are not continuous with present-day climate research. For example, he suggested that increasing the carbon dioxide content of the atmosphere by burning fossil fuels might be beneficial, making the Earth's climates warmer and “more equable,” stimulating plant growth, and providing more food for a larger population [Arrhenius, 1908]. Arrhenius's view of the potentially beneficial effects of carbon dioxide emissions differs radically from current concerns over the harmful effects of a global warming caused by industrial activity and deforestation [Fleming, 1998].

  11. Twenty Years of Continuous gas Release at Kilauea: Effusive Lessons in a Volatile Time

    NASA Astrophysics Data System (ADS)

    Sutton, A. J.; Elias, T.

    2002-12-01

    source. The emissions are converted by oxygen, moisture and sunlight to a mixture of gases and sub-micron acidic particles capable of being drawn and retained deep in the lung. When the northeasterly trade winds, which prevail more than 75% of the year, are disrupted, emissions build up in east, rather than west Hawai`i. The acidic nature of vog causes unquantified respiratory effects, rapidly corrodes metal objects, damages crops, degrades domestic water quality and has been linked to decreased rainfall in downwind areas on the island of Hawai`i. Unlike the mostly episodic nature of earthquakes and lava flows that have become the signature of hazards during the eruption, volcanic air pollution has been a nearly continuous albeit low-level hazard since 1986. Depending upon wind direction, some portion of the island and its 150,000 residents are affected. During trade wind disruptions, Oahu, 300 km northwest, is impacted as well. Vog buildup in east Hawai`i degrades air quality for residents and also for some of Hawai`i National Park's 2.3 million annual visitors. The emissions have taken at least one life directly, and asthma deaths island-wide, probably caused in part by Kilauea's large SO2 emissions, exceeded predictions by 300 percent after the eruption became continuous. Health care professionals, scientists and educators are currently working with the community to define vog's health effects. While this hazard evaluation proceeds, the USGS, in collaboration with the National Park Service, has developed a real-time system to inform and advise park visitors and employees when vog levels, as approximated by ambient SO2 concentration, exceeds preset levels.

  12. The Relationship between Perceived and Ideal Body Size and Body Mass Index in 3rd-Grade Low Socioeconomic Hispanic Children

    ERIC Educational Resources Information Center

    Fisher, Allison; Lange, Mary Anne; Young-Cureton, Virginia; Canham, Daryl

    2005-01-01

    Very little is known about body satisfaction among minority children. This study examined the relationship between perceived and actual body size and Body Mass Index among 43 low-socioeconomic Hispanic 3rd-graders. Researchers measured participants' Body Mass Index; students self-reported Perceived Ideal Self Image and Perceived Actual Self Image…

  13. "Elderly Deafblindness." Proceedings of the European Conference of Deafblind International's Acquired Deafblindness Network (3rd, Marcelli di Numana, Italy, October 2-7, 1998).

    ERIC Educational Resources Information Center

    Deafblind International, London (England).

    This text includes all of the plenary presentations from the 3rd European Conference of Deafblind International's Acquired Deafblindness Network. This international conference was the first to focus specifically on older people with dual sensory impairment. Presentations addressed the awareness of the needs of older people with deafblind or dual…

  14. Implications of Technology for Teaching and Learning. Annual Professional Education Seminar of Central States Colleges and Universities (3rd, November, 1967).

    ERIC Educational Resources Information Center

    Woodruff, Asahel; Froyen, Len

    This report of the proceedings of the 3rd Annual Professional Education Seminar of the Central States Colleges and Universities centers upon the implications of technology for teaching and learning and contains addresses delivered, including "Some Concerns Related to Technology in Education," by Len Froyen; and "Implications of Technology for…

  15. Molecular characteristics of continuously released DOM during one year of root and leaf litter decomposition

    NASA Astrophysics Data System (ADS)

    Altmann, Jens; Jansen, Boris; Kalbitz, Karsten; Filley, Timothy

    2013-04-01

    Dissolved organic matter (DOM) is one of the most dynamic carbon pools linking the terrestrial with the aquatic carbon cycle. Besides the insecure contribution of terrestrial DOM to the greenhouse effect, DOM also plays an important role for the mobility and availability of heavy metals and organic pollutants in soils. These processes depend very much on the molecular characteristics of the DOM. Surprisingly the processes that determine the molecular composition of DOM are only poorly understood. DOM can originate from various sources, which influence its molecular composition. It has been recognized that DOM formation is not a static process and DOM characteristics vary not only between different carbon sources. However, molecular characteristics of DOM extracts have scarcely been studied continuously over a longer period of time. Due to constant molecular changes of the parent litter material or soil organic matter during microbial degradation, we assumed that also the molecular characteristics of litter derived DOM varies at different stages during root and needle decomposition. For this study we analyzed the chemical composition of root and leaf samples of 6 temperate tree species during one year of litter decomposition in a laboratory incubation. During this long-term experiment we measured continuously carbon and nitrogen contents of the water extracts and the remaining residues, C mineralization rates, and the chemical composition of water extracts and residues by Curie-point pyrolysis mass spectrometry with TMAH We focused on the following questions: (I) How mobile are molecules derived from plant polymers like tannin, lignin, suberin and cutin? (II) How does the composition of root and leaf derived DOM change over time in dependence on the stage of decomposition and species? Litter derived DOM was generally dominated by aromatic compounds. Substituded fatty acids as typically cutin or suberin derived were not detected in the water extracts. Fresh leaf and

  16. The 2000 National Survey of First-Year Programs: Continuing Innovations in the Collegiate Curriculum. The First-Year Experience Monograph Series.

    ERIC Educational Resources Information Center

    South Carolina Univ., Columbia. National Resource Center for the First-Year Experience and Students in Transition.

    Since the first National Survey on Freshman Seminar Programs was conducted in fall 1988, the National Resource Center for The First-Year Experience and Students in Transition has continued to investigate, triennially, the extent to which first-year seminars are offered on college campuses across the United States. Data in this publication provide…

  17. Electrocradiographic Qrs Axis, Q Wave and T-wave Changes in 2nd and 3rd Trimester of Normal Pregnancy

    PubMed Central

    S., Chandrasekharappa; Brid, S.V

    2014-01-01

    Background: Pregnancy although a physiological phenomena affects all the functions of the maternal body and brings about remarkable changes in the cardiovascular system. The cardiovascular changes and many of the physiological adaptations of normal pregnancy alter the physical findings thus, sometimes misleading the diagnosis of heart disease. Pregnancy also brings about various changes in the electrocardiogram, further confusing with that of heart disease. This study is undertaken to highlight the effect of normal pregnancy on the QRS axis, Q wave and T-wave of the Electrocardiogram and thereby helps us to distinguish it from that of pathological changes. Objectives: To study the effect of normal pregnancy on the QRS axis, Q wave and T-wave in the electrocardiogram and to compare with that of normal non pregnant women. Materials and Methods: Fifty normal pregnant women in 2nd and 3rd trimester each between 20– 35 y of age and 50 normal non pregnant women of the same age group were selected for the study. A 12 lead ECG was recorded by using ECG machine with special emphasis on QRS axis, Q wave and T-wave changes and all the parameters were analysed. Results: The ECG changes observed in our study include, deviation of QRS axis towards left as pregnancy advanced, significant increased incidence of occurrence of prominent Q waves in lead II, III and avF in pregnant group (p < 0.05 ) and, T-wave abnormalities like flat and inverted T-waves in lead III, V1 – V3 were more frequent in pregnant group ( p<0.05 ) than in non pregnant group. Conclusion:Normal pregnancy brings about various changes in ECG. These changes during pregnancy should be interpretated with caution by the physicians. It is necessary to understand the normal physiological changes which in turn help us in better management of those with cardiac disease. PMID:25386425

  18. One year continuous soil gas monitoring above an EGR test site

    NASA Astrophysics Data System (ADS)

    Furche, Markus; Schlömer, Stefan; Faber, Eckhard; Dumke, Ingolf

    2010-05-01

    Setup and first results of an ongoing research activity are presented, which is funded by the German Geotechnologien program within in the joint project CLEAN (CO2 Large Scale Enhanced Gas Recovery in the Altmark Natural Gas Field). The task is to establish several soil gas monitoring stations above a partly exhausted gas field in the Altmark which will be used for an enhanced gas recovery (EGR) test by injecting CO2 into the reservoir. The aim is to optimize the monitoring technique including automatic data transfer and data exploitation and to understand mechanisms of natural variations of soil gas concentrations in the specific area. Furthermore the suitability of these measurements as a contribution to leakage detection shall be evaluated. A network of 13 gauging stations for the measurement of CO2 is working continuously for about one year. They are spread over an area of 8 x 3 km and are situated in direct vicinity of existing deep boreholes as the most likely locations for possible leakage. In addition one station is placed far outside the gasfield as a reference point. The technique applied to measure soil gas concentrations uses a gas stream circulating in a tube going down a shallow borehole where the circulating gas is in contact with the soil gas phase via a gas permeable membrane. Above surface, moisture is removed from the gas stream before it reaches several gas sensors for CO2. Besides these, several other parameters are determined as well, e.g. soil moisture and soil temperature, water level, gas flow and gas moisture. In addition a meteorological station gives information about precipitation, air humidity, temperature and pressure, global radiation, wind direction and velocity in the area. Data are continuously collected by dataloggers at each station (5 minutes interval), transferred via GSM routers to the BGR server in Hannover and are stored in a specially designed database. The database does not only contain the measurements but also

  19. Making further continuing appropriations for fiscal year 2012, and for other purposes.

    THOMAS, 112th Congress

    Rep. Rogers, Harold [R-KY-5

    2011-12-16

    12/17/2011 Became Public Law No: 112-68. (TXT | PDF) (All Actions) Notes: Continuing appropriations through 12/23/2011. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  20. Making further continuing appropriations for fiscal year 2015, and for other purposes.

    THOMAS, 113th Congress

    Rep. Rogers, Harold [R-KY-5

    2014-12-10

    12/12/2014 Became Public Law No: 113-202. (TXT | PDF) (All Actions) Notes: Continuing appropriations through 12/13/2014. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  1. Making further continuing appropriations for fiscal year 2015, and for other purposes.

    THOMAS, 113th Congress

    Rep. Rogers, Harold [R-KY-5

    2014-12-12

    12/13/2014 Became Public Law No: 113-203. (TXT | PDF) (All Actions) Notes: Continuing appropriations through 12/17/2014. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  2. Making further continuing appropriations for fiscal year 2012, and for other purposes.

    THOMAS, 112th Congress

    Rep. Rogers, Harold [R-KY-5

    2011-12-16

    12/16/2011 Became Public Law No: 112-67. (TXT | PDF) (All Actions) Notes: Continuing appropriations through 12/17/2011. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  3. South Dakota continuing dental education using open-circuit television: two-year report

    ERIC Educational Resources Information Center

    Watkins, Frances H.; Ludeman, D. R.

    1973-01-01

    Establishment of an effective communication system, quality programing material, and development of viewer expectation of the programs are essential for the use of educational television in continuing dental education. (Editor)

  4. Making further continuing appropriations for fiscal year 2014, and for other purposes.

    THOMAS, 113th Congress

    Rep. Rogers, Harold [R-KY-5

    2014-01-10

    01/15/2014 Became Public Law No: 113-73. (TXT | PDF) (All Actions) Notes: Continuing appropriations through 1/18/2014. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  5. Making further continuing appropriations for fiscal year 2009, and for other purposes.

    THOMAS, 111th Congress

    Rep. Obey, David R. [D-WI-7

    2009-03-06

    03/06/2009 Became Public Law No: 111-6. (TXT | PDF) (All Actions) Notes: Continuing appropriations through 3/11/2009. Tracker: This bill has the status Became LawHere are the steps for Status of Legislation:

  6. In vitro cultivation of Hysterothylacium aduncum (Nematoda: Anisakidae) from 3rd-stage larvae to egg-laying adults.

    PubMed

    Iglesias, L; Valero, A; Gálvez, L; Benítez, R; Adroher, F J

    2002-11-01

    This is the first demonstration of the in vitro development of the 3rd-stage larvae (L3) of Hysterothylacium aduncum to the adult. This was achieved in a semi-defined medium that is easy to prepare and to reproduce. The L3, collected from the peritoneal cavity of horse mackerel (Trachurus trachurus), were individually inoculated into RPMI-1640 medium +20% heat-inactivated fetal bovine serum (IFBS). It has been demonstrated that the optimum temperature for development is around 13 degrees C and is stimulated by the presence of 5% CO2 in the growth atmosphere, increasing the percentage moulting to the 4th larval stage (L4) by 1.9-fold (from 44 to 82%) and the average survival of the nematodes by 1.6 times (from 60 to 96 days). When the larvae were grown at different pHs, optimum development occurred at pH 4.0. Under these conditions, all the larvae moulted to the L4 and more than two-thirds transformed to the adult stage--in which 25-30% of the females laid eggs--and reached an average survival of over 4 months. When this medium was supplemented with 1% (w/v) of commercial pepsin, all the larvae reached the adult stage, at least 45% of the females oviposited, laying around 12-fold more eggs per female than in the medium without pepsin. The mean size of the eggs (non-fertilized) obtained was 56.8 x 47.6 microm. The mean length of the adult males obtained was between 3.2 and 5.2 cm and the females were between 3.0 and 6.5 cm. The adult specimens were morphologically identified as Hysterothylacium aducum aduncum. This culture medium (RPMI-1640+20% (v/v) IFBS+1 commercial pepsin, at pH 4.0, 13 degrees C and 5% CO2 in air) could facilitate the identification of at least some of the larvae of the genus Hysterothylacium--and perhaps other anisakids--for which the specific identification and the biological study of these parasites is often difficult. PMID:12458831

  7. Real-World Use of 3rd Line Therapy for Multiple Myeloma in Austria: An Austrian Myeloma Registry (AMR) Analysis of the Therapeutic Landscape and Clinical Outcomes prior to the Use of Next Generation Myeloma Therapeutics

    PubMed Central

    Willenbacher, Ella; Weger, Roman; Rochau, Ursula; Siebert, Uwe; Willenbacher, Wolfgang

    2016-01-01

    Objective Clinical trials demonstrate improving survival in patients with multiple myeloma (MM) after treatment. However, it is unclear whether increased survival translates to a similar benefit in a real world setting. Methods We analyzed the overall survival of 347 multiple myeloma patients in Austria by means of a national registry (AMR), focused on results from 3rd and later lines of therapy. This benchmark was chosen to define a baseline prior to the broad application of upcoming 2nd generation drugs (carfilzomib, pomalidomide). Results Projected 10 years survival for patients with MM in Austria is estimated to be 56% in patients diagnosed in between the years 2011–2014, 21% in patients with a diagnosis made between 2000–2005, and 39% in those with a diagnosis made between 2006–2010). For the same intervals a significant increase in the use of both bortezomib, lenalidomide and thalidomide—so called IMiDs (from 2005 onwards) and their simultaneous use in combination therapies (from 2010 onwards) could be shown. The use of autologous transplantation (ASCT) remained more or less constant at ~ 35% of patients in the 1st line setting over the whole period, comparing well to international practice patterns, while the use of 2nd line ASCT increased from 5.5% to 18.7% of patients. Patients in 3rd or later line treatment (n = 105), showed that even in relapsed and refractory disease median survival was 27 months with a considerable proportion of long-term survivors (~20%). Conclusion & Perspective With the expected emergence of additional active anti-myeloma compounds, we aim to assess survival in patients with relapsed and refractory MM. PMID:26937956

  8. Information Processing from Infancy to 11 Years: Continuities and Prediction of IQ

    ERIC Educational Resources Information Center

    Rose, Susan A.; Feldman, Judith F.; Jankowski, Jeffery J.; Van Rossem, Ronan

    2012-01-01

    This study provides the first direct evidence of cognitive continuity for multiple specific information processing abilities from infancy and toddlerhood to pre-adolescence, and provides support for the view that infant abilities form the basis of later childhood abilities. Data from a large sample of children (N = 131) were obtained at five…

  9. Assessment of the Continuous Progress Report for the Early Learning Years (An Examination of Scale Construction).

    ERIC Educational Resources Information Center

    Tuck, Kathy D.

    An evaluation was conducted to examine the structure and design of the Continuous Progress Report (CPR), an observation scale used to measure students' early developmental skills in the District of Columbia public schools. Item construction and the relative consistency of measurement constructs in the CPR were the specific focus of the evaluation.…

  10. Child and Mother Cardiac Vagal Tone: Continuity, Stability, and Concordance across the First 5 Years.

    ERIC Educational Resources Information Center

    Bornstein, Marc H.; Suess, Patricia E.

    2000-01-01

    Measured vagal tone and heart period at 2 months and 5 years in children and their mothers to evaluate the development of vagal regulation at rest and during an environmental task. Found that children reached adult levels of baseline vagal tone by 5 years and did not differ from mothers in baseline-to-task change in vagal tone or heart period.…

  11. Supplemental Instruction: Improving First-Year Student Success in High-Risk Courses. 3rd Edition. The First-Year Experience Monograph Series No. 7

    ERIC Educational Resources Information Center

    Stone, Marion E., Ed.; Jacobs, Glen, Ed.

    2008-01-01

    This monograph describes Supplemental Instruction, a student assistance program designed to improve the academic success of college freshmen based on the idea that if students are not being successful in courses then perhaps colleges should change the way courses are taught. Supplemental Instruction (SI) utilizes regularly scheduled, out-of-class,…

  12. Three-Year Chemical Dependency and Mental Health Treatment Outcomes Among Adolescents: The Role of Continuing Care

    PubMed Central

    Sterling, Stacy; Chi, Felicia; Campbell, Cynthia; Weisner, Constance

    2010-01-01

    Background Few studies have examined the effects of treatment factors, including the types of services [chemical dependency (CD), psychiatric, or both], on long-term outcomes among adolescents following CD treatment, and whether receiving continuing care may contribute to better outcomes. This study examines the effect of the index CD and ongoing CD and psychiatric treatment episodes, 12-step participation, and individual characteristics such as CD and mental health (MH) severity and gender, age, and ethnicity, on 3-year CD and MH outcomes. Methods Participants were 296 adolescents aged 13 to 18 seeking treatment at 4 CD programs of a nonprofit, managed care, integrated health system. We surveyed participants at intake, 1 year, and 3 years, and examined survey and administrative data, and CD and psychiatric utilization. Results At 3 years, 29.7% of the sample reported total abstinence from both alcohol and drugs (excluding tobacco). Compared with girls, boys had only half the odds of being abstinent (OR = 0.46, p = 0.0204). Gender also predicted Externalizing severity at 3 years (coefficients 18.42 vs. 14.77, p < 0.01). CD treatment readmission in the second and third follow-up years was related to abstinence at 3 years (OR = 0.24, p = 0.0066 and OR = 3.33, p = 0.0207, respectively). Abstinence at 1 year predicted abstinence at 3 years (OR = 4.11, p < 0.0001). Those who were abstinent at 1 year also had better MH outcomes (both lower Internalizing and Externalizing scores) than those who were not (11.75 vs. 15.55, p = 0.0012 and 15.13 vs. 18.06, p = 0.0179, respectively). Conclusions A CD treatment episode resulting in good 1-year CD outcomes may contribute significantly to both CD and MH outcomes 3 years later. The findings also point to the value of providing a continuing care model of treatment for adolescents. PMID:19413644

  13. [Continuous spectrum analysis during anesthesia and the recovery period in infants under 1 year of age].

    PubMed

    Meyer, P; Bensouda, A; Mayer, M N; Barrier, G

    1989-01-01

    Continuous spectral EEG activity monitoring has been used in adults as a monitor of brain activity during anesthesia. It has not been used in infants. We studied 22 infants less than 7 months old undergoing minor surgery. Halothane alone or minimal Halothane anesthesia associated with caudal epidural anesthesia were used. Life-Scan analysis, in spite of wide individual variations, allowed us to detect infraclinical hypoxia episodes, it provided informations about operative confort, depth of anesthesia and added in the post-operative period an objective criteria to clinical evaluation of pain. A wide use of such a monitoring is warranted in infants.

  14. [Continuous spectrum analysis during anesthesia and the recovery period in infants under 1 year of age].

    PubMed

    Meyer, P; Bensouda, A; Mayer, M N; Barrier, G

    1989-01-01

    Continuous spectral EEG activity monitoring has been used in adults as a monitor of brain activity during anesthesia. It has not been used in infants. We studied 22 infants less than 7 months old undergoing minor surgery. Halothane alone or minimal Halothane anesthesia associated with caudal epidural anesthesia were used. Life-Scan analysis, in spite of wide individual variations, allowed us to detect infraclinical hypoxia episodes, it provided informations about operative confort, depth of anesthesia and added in the post-operative period an objective criteria to clinical evaluation of pain. A wide use of such a monitoring is warranted in infants. PMID:2631593

  15. Inflation of Long Valley Caldera from 1 year of continuous GPS observations

    NASA Technical Reports Server (NTRS)

    Webb, Frank H.; Bursik, Marcus; Dixon, Timothy; Farina, Frederic; Marshall, Grant; Stein, Ross S.

    1995-01-01

    A permanent Global Positioning System (GPS) receiver at Casa Diablo Hot Springs, Long Valley Caldera, California was installed in January, 1993, and has operated almost continuously since then. The data have been transmitted daily to the Jet Propulsion Laboratory (JPL) for routine analysis with data from the Fiducial Laboratories for an International Natural sciences Network (FLINN) by the JPL FLINN analysis center. Results from these analyses have been used to interpret the on going deformation at Long Valley, with data excluded from periods when the antenna was covered under 2.5 meters of snow and from some periods when Anti Spoofing was enforced on the GPS signal. The remaining time series suggests that uplift of the resurgent dome of Long Valley Caldera during 1993 has been 2.5 +/- 1.1 cm/yr and horizontal motion has been 3.0 +/- 0.7 cm/yr at S53W in a no-net-rotation global reference frame, or 1.5 +/- 0.7 cm/yr at S14W relative to the Sierra Nevada block. These rates are consistent with uplift predicted from frequent horizontal strain measurements. Spectral analysis of the observations suggests that tidal forcing of the magma chamber is not a source of the variability in the 3 dimensional station location. These results suggest that remotely operated, continuously recording GPS receivers could prove to be a reliable tool for volcanic monitoring throughout the world.

  16. Inflation of Long Valley Caldera from 1 year of continuous GPS observations

    NASA Astrophysics Data System (ADS)

    Webb, Frank H.; Bursik, Marcus; Dixon, Timothy; Farina, Frederic; Marshall, Grant; Stein, Ross S.

    1995-02-01

    A permanent Global Positioning System (GPS) receiver at Casa Diablo Hot Springs, Long Valley Caldera, California was installed in January, 1993, and has operated almost continuously since then. The data have been transmitted daily to the Jet Propulsion Laboratory (JPL) for routine analysis with data from the Fiducial Laboratories for an International Natural sciences Network (FLINN) by the JPL FLINN analysis center. Results from these analyses have been used to interpret the on going deformation at Long Valley, with data excluded from periods when the antenna was covered under 2.5 meters of snow and from some periods when Anti Spoofing was enforced on the GPS signal. The remaining time series suggests that uplift of the resurgent dome of Long Valley Caldera during 1993 has been 2.5 +/- 1.1 cm/yr and horizontal motion has been 3.0 +/- 0.7 cm/yr at S53W in a no-net-rotation global reference frame, or 1.5 +/- 0.7 cm/yr at S14W relative to the Sierra Nevada block. These rates are consistent with uplift predicted from frequent horizontal strain measurements. Spectral analysis of the observations suggests that tidal forcing of the magma chamber is not a source of the variability in the 3 dimensional station location. These results suggest that remotely operated, continuously recording GPS receivers could prove to be a reliable tool for volcanic monitoring throughout the world.

  17. Public Relations in Catholic Secondary Schools: Nearly 40 Years of Continuous Improvement

    ERIC Educational Resources Information Center

    James, John T.

    2004-01-01

    This article traces the phenomenal improvement in public relations efforts over the past 40 years made by Catholic secondary schools. The improvements were brought about by crises, a theological paradigm shift, professional lay involvement, a growing awareness and appreciation of public relations, competition, and increasing financial need. The…

  18. Social Representations of Educability in Finland: 20 Years of Continuity and Change

    ERIC Educational Resources Information Center

    Raty, Hannu; Komulainen, Katri; Hirva, Laura

    2012-01-01

    This study set out to replicate a survey conducted 20 years ago on Finnish parents' social representations of educability. A nationwide sample of parents (N = 642) were asked to indicate their opinions on a set of statements pertaining to topical educational issues. The results indicated that educational discussion is still structured by two major…

  19. Exploring the Continuing Professional Development Needs of Pedagogical Practitioners in Early Years in England

    ERIC Educational Resources Information Center

    Ingleby, Ewan; Hedges, Clive

    2012-01-01

    This article is based on quantitative and qualitative data that have been generated since 2009 on the study skills needs of early years practitioners working in England. The research has identified that developing information technology skills appears to be a particular professional development need for these practitioners. The practitioners are…

  20. Fifty years of continuous improvement: (What has DOE done for analytical chemistry?)

    SciTech Connect

    Shults, W.D.

    1993-11-01

    Over the past fifty years, analytical scientist within the DOE complex have had a tremendous impact on the field of analytical chemistry. This paper suggests six ``high impact`` research/development areas that either originated within or were brought to maturity within the DOE laboratories. ``High impact`` means they lead to new subdisciplines or to new ways of doing business.

  1. New Voices: In Its Fifth Year, Journalism Project Continues to Train Hispanics in Writing and Reporting

    ERIC Educational Resources Information Center

    Stuart, Reginald

    2011-01-01

    In this article, the author features a new multimedia, bilingual communications class called Borderzine. With an initial $15,000 seed grant from the Ford Foundation and soon afterward a four-year $400,000 grant from the John S. and James L. Knight Foundation, Borderzine is approaching its fifth anniversary with much to celebrate about its efforts…

  2. End of Life Operations for LEO and GEO Satellites: 30 Years of Continuous Improvement

    NASA Astrophysics Data System (ADS)

    Fremeaux, Claire; Moussi, Aurelie; Vintenat, Lionel; Moulin, Michel

    2013-08-01

    CNES is celebrating in 2013 its 40th year of satellites operations with nearly 40 satellites cared for from Symphony 1 (1973) to Pleiades 1B (2012). Half of them reached its end of mission. Although they were not designed for it, CNES imagined, prepared and executed end-of life operations for geostationary and low earth orbit satellites, in accordance with its strong involvement at international level in favour of space activity sustainability and space debris mitigation. With increasing experience, efficiency and completeness of operations have strongly improved: optimization of resources, precise orbit and eccentricity management, collision risk concern, controlled fluidic and electric passivation, concern for degraded or emergency cases… This paper presents the evolution and improvement of end of life operations handled by CNES for 30 years, with a highlight on the last evolutions in the whole process since the French Space Act came into force.

  3. [Continuously do a good job in planned parenthood work and fulfill this year's population target].

    PubMed

    Yang, H

    1981-09-24

    It has been a year since the CCP Central Committee issued an open letter to all CCP and CYL members on population control. In the past year, CCP and CYL members and the broad masses of people in our province have actively responded to the CCP Central Committee's call--1 child/couple. Over 1.7 million couples of childbearing age have applied for only-child certificates. Our province has scored great achievements in planned parenthood work. However, we must realize that new situations and new questions have arisen in planned parenthood work. 1st, the peak period of population growth in our province is from the late 1950s to the 1960s. Children born in this period are now entering the childbearing age. There soon will be a new peak population growth period. 2nd, because of the enactment of the new marriage law, the number of those married in the first 1/2 of this year doubled that of previous years. Responsibility systems in rural areas have pomoted development of productive forces. This is very good, but this has also stimulated population growth because people mistakenly think that more children mean more labor forces and more income. They begin to think of having more chidlren--especially sons. Some localities have lost control of population growth. The birth rate in rural areas has begun to climb quickly. If no measures are adopted immediately, our province's population will swell enormously. All the achievements scored in the 1970s will probably be spoiled, and we likely will again commit a historical error. As far as our province is concerned, planned parenthood is imperative. In 1949, our province's per capita farmland was 3 mu. At the end of 1980, it was only 1.49 mu. If no measures are adopted and the population keeps growing, the consequences will be serious.

  4. Proceedings of the Midwest Research-to-Practice Conference in Adult and Continuing Education (3rd, DeKalb, Illinois, September 27-28, 1984).

    ERIC Educational Resources Information Center

    Northern Illinois Univ., De Kalb. Coll. of Continuing Education.

    These proceedings consist of 28 presentations. They include, in alphabetical order by author, "Data Collection Methods Used to Determine Training Needs of the Organization and the Adult Learner in Business and Industry" (Bart P. Beaudin), "Sex and the Split Brain: Does the Sex of the Mind Matter?" (Anne A. Bowbeer), "Understanding the Anima/Animus…

  5. Continuous 500,000-year climate record from vein calcite in Devils Hole, Nevada

    USGS Publications Warehouse

    Winograd, I.J.; Coplen, T.B.; Landwehr, J.M.; Riggs, A.C.; Ludwig, K. R.; Szabo, B. J.; Kolesar, Peter T.; Revesz, K.M.

    1992-01-01

    Oxygen-18 (??18O) variations in a 36-centimeter-long core (DH-11) of vein calcite from Devils Hole, Nevada, yield an uninterrupted 500,000-year paleotemperature record that closely mimics all major features in the Vostok (Antarctica) paleotemperature and marine ??18O ice-volume records. The chronology for this continental record is based on 21 replicated mass-spectrometric uranium-series dates. Between the middle and latest Pleistocene, the duration of the last four glacial cycles recorded in the calcite increased from 80,000 to 130,000 years; this variation suggests that major climate changes were aperiodic. The timing of specific climatic events indicates that orbitally controlled variations in solar insolation were not a major factor in triggering deglaciations. Interglacial climates lasted about 20,000 years. Collectively, these observations are inconsistent with the Milankovitch hypothesis for the origin of the Pleistocene glacial cycles but they are consistent with the thesis that these cycles originated from internal nonlinear feedbacks within the atmosphere-ice sheet-ocean system.

  6. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest.

    PubMed

    Pearson, Scott F; Giovanini, Jack; Jones, Jay E; Kroll, Andrew J

    2015-01-01

    Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1-2 years) and long-term (~10 years) avian community responses (occupancy and abundance) to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13 m) forested buffers on each side of the stream, and sites with wider (~30 m) and more variable width unharvested buffer. Buffer treatments exhibited a 31-44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63-74%) relative to the controls (29%). We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals) for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29%) and Wide buffers (short-term: 21%; long-term 93%) relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that range from

  7. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest

    PubMed Central

    2015-01-01

    Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1–2 years) and long-term (~10 years) avian community responses (occupancy and abundance) to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13m) forested buffers on each side of the stream, and sites with wider (~30m) and more variable width unharvested buffer. Buffer treatments exhibited a 31–44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63–74%) relative to the controls (29%). We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals) for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29%) and Wide buffers (short-term: 21%; long-term 93%) relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that range

  8. Breeding Bird Community Continues to Colonize Riparian Buffers Ten Years after Harvest.

    PubMed

    Pearson, Scott F; Giovanini, Jack; Jones, Jay E; Kroll, Andrew J

    2015-01-01

    Riparian ecosystems integrate aquatic and terrestrial communities and often contain unique assemblages of flora and fauna. Retention of forested buffers along riparian habitats is a commonly employed practice to reduce potential negative effects of land use on aquatic systems. However, very few studies have examined long-term population and community responses to buffers, leading to considerable uncertainty about effectiveness of this practice for achieving conservation and management outcomes. We examined short- (1-2 years) and long-term (~10 years) avian community responses (occupancy and abundance) to riparian buffer prescriptions to clearcut logging silvicultural practices in the Pacific Northwest USA. We used a Before-After-Control-Impact experimental approach and temporally replicated point counts analyzed within a Bayesian framework. Our experimental design consisted of forested control sites with no harvest, sites with relatively narrow (~13 m) forested buffers on each side of the stream, and sites with wider (~30 m) and more variable width unharvested buffer. Buffer treatments exhibited a 31-44% increase in mean species richness in the post-harvest years, a pattern most evident 10 years post-harvest. Post-harvest, species turnover was much higher on both treatments (63-74%) relative to the controls (29%). We did not find evidence of local extinction for any species but found strong evidence (no overlap in 95% credible intervals) for an increase in site occupancy on both Narrow (short-term: 7%; long-term 29%) and Wide buffers (short-term: 21%; long-term 93%) relative to controls after harvest. We did not find a treatment effect on total avian abundance. When assessing relationships between buffer width and site level abundance of four riparian specialists, we did not find strong evidence of reduced abundance in Narrow or Wide buffers. Silviculture regulations in this region dictate average buffer widths on small and large permanent streams that range from

  9. 5 years of continuous seismic monitoring of snowmelt cycles in a Pyrenean valley

    NASA Astrophysics Data System (ADS)

    Diaz, Jordi; Sánchez-Pastor, Pilar; Gallart, Josep

    2016-04-01

    In recent years the analysis of background seismic noise variations in the proximity of river channels has revealed as a useful tool to monitor river flow, even for modest discharges. We will focus here in the application of this methodology to study the snowmelt cycle in an Pyrenean valley during the last 5 years, using data from the seismic geophysical station located inside the Canfranc Underground Laboratory (Central Pyrenees). Diaz et al. (2014) first identified in the seismic data the signature of river flow increases associated to snowmelt episodes in the catchment area of the Aragon River, based on the marked correlation between the seismic energy variations in the 2-8 Hz frequency band and the estimated variations in water resources from snowfall. The analysis of seismic data during the snowmelt periods allows to identify a clear 24h cycle, with energy increasing from about 14:00 GMT, remaining at a relatively high level for 12 hours and then smoothly vanishing. The spectrogram reveals richer information, as clear variations in the frequency content can be detected during the time intervals in which the amplitude of the seismic signal remains constant. The data available so far allow to compare the evolution of snowmelt in five seasons with very different hydrological behavior. The 2011 and 2012 seasons have been dry, with snow volumes 30-50 % beneath the average values, while the 2013, 2014 and in particular the 2015 seasons have been largely above the mean. Those variations are reflected in the seismic data, which allow to monitor the time occurrence of the main snowmelt stages for each season and to estimate the intensity of the different snowmelt episodes. Therefore, seismic data can be useful for long term monitoring of snowmelt in Alpine-style mountains.

  10. Osteoporosis treatment: bisphosphonates reign to continue for a few more years, at least?

    PubMed

    Pazianas, Michael; Abrahamsen, Bo

    2016-07-01

    The findings of the Women's Health Initiative study in 2002 marginalized the use of hormone replacement therapy and established bisphosphonates as the first line of treatment for osteoporosis.  Denosumab could be used in selected patients. Although bisphosphonates only maintain the structure of bone complete with any accumulated structural or material faults, their bone selectivity and effectiveness in reducing the risk of fractures, together with their low cost, have left little room for improvement for new antiresorptives. The osteoanabolic teriparatide increases new bone formation, but it is administered for up to 2 years only and the cost remains a consideration. Similar restrictions are expected to apply to an anti-sclerostin antibody, which could be evaluated by the U.S. Food and Drug Administration in the near future. Cathepsin K-inhibiting antibody could be an alternative if approved; although an antiresorptive, it maintains bone formation, in contrast with bisphosphonates, and can be probably used for long-term treatment.  Rare adverse effects of bisphosphonates, namely osteonecrosis of the jaws and atypical femoral fractures, have been disproportionally emphasized relative to their benefits/harm ratio. Treatment of osteoporosis is a long process, and many patients will require treatment with more than one type of drug over their lifetime. PMID:27525578

  11. Still NAAG'ing After All These Years: The Continuing Pursuit of GCPII Inhibitors.

    PubMed

    Vornov, J J; Hollinger, K R; Jackson, P F; Wozniak, K M; Farah, M H; Majer, P; Rais, R; Slusher, B S

    2016-01-01

    Nearly two decades ago, Joe Coyle published a single-authored review with the provocative title, The Nagging Question of the Function of N-Acetylaspartylglutamate (Coyle, 1997). In this review, Coyle documented NAAG's localization to subpopulations of glutamatergic, cholinergic, GABAergic, and noradrenergic neurons, Ca(2+)-dependent release, mGlu3 receptor agonist and NMDA receptor antagonist activity, and cleavage by the glial enzyme glutamate carboxypeptidase II (GCPII). However, at the time of his review, NAAG's physiological function as a neurotransmitter remained elusive. Ironically his review was published months following the discovery of the first potent and selective GCPII inhibitor, 2-(phosphonomethyl)pentanedioc acid (2-PMPA) (Jackson et al., 1996). Over the ensuing decades, over a dozen independent laboratories used 2-PMPA and other GCPII inhibitors to elucidate two distinct neurotransmitter functions for NAAG. Under basal conditions, when GCPII activity is relatively low, intact NAAG dampens synaptic activity via presynaptic mGlu3 receptor activation and NMDA receptor blockade. However, under stimulated conditions, NAAG release and GCPII activity are enhanced resulting in excess glutamate generation, activating NMDA and other glutamate receptors, often pathologically. Diverse classes of GCPII inhibitors have been synthesized and shown to increase NAAG, decrease glutamate, and provide robust efficacy in many disease models wherein abnormal glutamatergic transmission is presumed pathogenic. In addition, over the past 20 years, basic questions regarding NAAG's synthesis, packaging into vesicles, and receptor selectivity profile have been eloquently elucidated. The purpose of this chapter is to summarize these advances and the promise of regulating NAAG metabolism through GCPII inhibition as a therapeutic strategy. PMID:27288079

  12. [Use of imaging methods in the current screening, diagnostics and treatment of breast cancer - Professional guidelines. 3rd Breast Cancer Consensus Meeting].

    PubMed

    Forrai, Gábor; Ambrózay, Éva; Bidlek, Mária; Borbély, Katalin; Kovács, Eszter; Lengyel, Zsolt; Ormándi, Katalin; Péntek, Zoltán; Riedl, Erika; Sebõ, Éva; Szabó, Éva

    2016-09-01

    Breast radiologists and nuclear medical specialists have refreshed their previous statement text during the 3rd Hungarian Breast Cancer Consensus Meeting. They suggest taking into consideration this actual protocol for the screening, diagnostics and treatment of breast tumors, from now on. This recommendation includes the description of the newest technologies, the recent results of scientific research, as well as the role of imaging methods in the therapeutic processes and the follow-up. Suggestions for improvement of the Hungarian current practice and other related issues as forensic medicine, media connections, regulations, and reimbursement are also detailed. The statement text has been cross-checked with the related medical disciplines. PMID:27579719

  13. Effect of non-erupted 3rd molars on distal roots and supporting structures of approximal teeth. A radiographic survey of 202 cases.

    PubMed

    Nemcovsky, C E; Libfeld, H; Zubery, Y

    1996-09-01

    Root resorption of 2nd molars in proximity to non-erupted 3rd molars has been widely reported. The purpose of this study was to determine the prevalence of root resorption in second molars adjacent to non-erupted third molars. Its association to age and gender of the patient, location and inclination of the non-erupted third molar and to distal bone support of the 2nd molars was analyzed. A radiographic survey of 202 periapical radiographs taken in patients with clinically missing third molars was conducted. 3 examiners independently evaluated the radiographs and only those cases where at least 2 observers agreed were included in this report. Statistical analysis was performed on 186 radiographs. Associations were analyzed with the Pearson chi 2 test. Radiographic evidence of root resorption was found in 45 2nd molars (24.2%) of which 12 (6.5%) showed moderate to complete root resorption. Non-erupted tooth apical position and mesio-inclination of 60 degrees or more relative to the distal root of the second molar were significantly associated with root resorption (p = 0.01368 and p = 0.0194, respectively). Resorption was positively associated with age of patient (p = 0.00606). These results may support early extraction of impacted 3rd molars especially in cases with a mesio-angulation of 60 degrees or more and an apical location in proximity to the distal root of the 2nd molar. PMID:8891930

  14. Proceedings of the Conference: Universities in World Network of Information and Communication (3rd, Dubrovnik, May 20-23, 1980).

    ERIC Educational Resources Information Center

    Soucek, Branko, Ed.

    1980-01-01

    The study, exploration, and debate of relations between universities, world information systems, and communication networks seeking to establish a sustainable system to handle recent developments in information and communication, utilizing universities as focal points, was continued at this third annual conference attended by 31 information…

  15. Collaborative study for the establishment of the WHO 3(rd) International Standard for Endotoxin, the Ph. Eur. endotoxin biological reference preparation batch 5 and the USP Reference Standard for Endotoxin Lot H0K354.

    PubMed

    Findlay, L; Desai, T; Heath, A; Poole, S; Crivellone, M; Hauck, W; Ambrose, M; Morris, T; Daas, A; Rautmann, G; Buchheit, K H; Spieser, J M; Terao, E

    2015-01-01

    An international collaborative study was organised jointly by the World Health Organization (WHO)/National Institute for Biological Standards and Control (NIBSC), the United States Pharmacopeia (USP) and the European Directorate for the Quality of Medicines & HealthCare (EDQM/Council of Europe) for the establishment of harmonised replacement endotoxin standards for these 3 organisations. Thirty-five laboratories worldwide, including Official Medicines Control Laboratories (OMCLs) and manufacturers enrolled in the study. Three candidate preparations (10/178, 10/190 and 10/196) were produced with the same material and same formulation as the current reference standards with the objective of generating a new (3(rd)) International Standard (IS) with the same potency (10 000 IU/vial) as the current (2(nd)) IS, as well as new European Pharmacopoeia (Ph. Eur.). and USP standards. The suitability of the candidate preparations to act as the reference standard in assays for endotoxin performed according to compendial methods was evaluated. Their potency was calibrated against the WHO 2(nd) IS for Endotoxin (94/580). Gelation and photometric methods produced similar results for each of the candidate preparations. The overall potency estimates for the 3 batches were comparable. Given the intrinsic assay precision, the observed differences between the batches may be considered unimportant for the intended use of these materials. Overall, these results were in line with those generated for the establishment of the current preparations of reference standards. Accelerated degradation testing of vials stored at elevated temperatures supported the long-term stability of the 3 candidate preparations. It was agreed between the 3 organisations that batch 10/178 be shared between WHO and EDQM and that batches 10/190 and 10/196 be allocated to USP, with a common assigned value of 10 000 IU/vial. This value maintains the continuity of the global harmonisation of reference materials and

  16. Beyond the Walls. 50 Years of Adult and Continuing Education at the University of Leeds, 1946-1996. Leeds Studies in Continuing Education.

    ERIC Educational Resources Information Center

    Taylor, Richard, Ed.

    This book contains 21 papers detailing the history of adult and continuing education at the University of Leeds (England) since its inception in 1946 as the Department of Extra-Mural Studies. The themes addressed include the appropriate nature of university continuing education and the issue of standards and quality assurance; the roles of…

  17. Contributions to global earth sciences integration. A special issue on the 3rd Young Earth Scientists Congress

    NASA Astrophysics Data System (ADS)

    Cónsole-Gonella, Carlos; Yidana, Sandow Mark

    2016-10-01

    The Young Earth Scientists (YES) Network is an association of early-career geoscientists who are primarily under the age of 35 years from universities, geoscience organizations and companies from across the world (http://www.networkyes.org)

  18. Prevalence of onchocerciasis in the Fundong Health District, Cameroon after 6 years of continuous community-directed treatment with ivermectin

    PubMed Central

    Kamga, Henri Lucien Fouamno; Shey, Dickson Nsagha; Assob, Jules Clement Nguedia; Njunda, Anna Longdoh; Nde Fon, Peter; Njem, Peter Kindong

    2011-01-01

    Introduction Onchocerciasis is one of the leading infectious causes of blindness affecting over 37 million people of which 99% are in Africa. The purpose of this study was to determine the prevalence of onchocerciasis in the Fundong Health District, a locality where community-directed treatment with ivermectin has been carried out for 6 consecutive years. Methods Questionnaires covering participants’ identity, Rapid Epidemiological Assessment (REA) for onchocerciasis and parasitological parameters were distributed to participants. Skin snip (SS) was collected for laboratory investigation. Results A total of 404 participants belonging to 200 households were randomly selected from the Fundong Health District, of which 134 (33.2%) were males and 270(66.8%) were females, 14 (3.5%) had microfilaredermia and 15(3.7%) had nodules. There was no significant difference in the prevalence of microfilaredermia with respect to age of participants (X2=2.749, P=0.601). There was however a statistically significant difference in the prevalence of nodule and impaired vision/eye itching (IVIE) with respect to age (X2=24.67, P<0.001). The greatest rate of infection was found among farmers (2.5%) followed by students (0.7%) and businessmen (0.25%). Conclusion This study shows that the study area is now hypo-endemic for onchocerciasis, following 6 years of continuous treatment with ivermectin. Careful monitoring of onchocerciasis should however be continued to avoid that the area returns to its initial hyper endemicity. PMID:22187616

  19. A year-long continuous Large Eddy Simulation of actual weather: subgrid and spatio-temporal scale issues

    NASA Astrophysics Data System (ADS)

    Jonker, Harmen; Verzijlbergh, Remco

    2016-04-01

    We analyse results of a single, continuous Large-Eddy Simulation of actual weather conditions during the timespan of a full year, made possible through recent computational developments (Schalkwijk et al, MWR, 2015). The simulation is coupled to a regional weather model in order to provide an LES dataset that is representative of the daily weather of the year 2012 around Cabauw, the Netherlands. This location is chosen such that LES results can be compared with both the regional weather model and observations from the Cabauw observational supersite. The simulation yields a data-set of relevant atmospheric variables that cover a scale range from seconds to seasons. Analysis of the spatial and temporal spectra of wind and thermodynamical quantities reveals the scale mismatches that arise from the coupling to the large-scale weather model, and provides information on how to better choose the domain size of the LES. In addition, as the single continuous run encompasses many different days and nights with widely varying atmospheric stabilities, we will discuss the high demands that are put on the LES subgrid model.

  20. Aims of the 3rd international course on the Law of Armed Conflict of the International Committee for Military Medicine.

    PubMed

    Baer, Hans-Ulrich; Gilgen, Peter

    2002-08-01

    The International Committee for Military Medicine (ICMM) decided at the 32nd Congress in Vienna in 1998 to give the Surgeon General of the Swiss Armed Forces the mandate to organize its international courses on the Law of Armed Conflict (LOAC). The Swiss Federal Government fully honored and endorsed its obligation to organize these important international courses. It is in the continuing tradition of Switzerland, as a small neutral state, to support humanitarian help and all efforts to prevent war. As decided by the head of the government on April 3, 1998, the mandate of the LOAC Courses will be funded by the Swiss Confederation.

  1. 25 years long-term deformation at Mt. Etna Continuous Borehole Tilt and Vertical GPS Displacements recordings

    NASA Astrophysics Data System (ADS)

    Bonaccorso, Alessandro; Bonforte, Alessandro; Gambino, Salvatore

    2016-04-01

    In the 1980s, shallow borehole tilt measurements saw a reprise in the monitoring of geodynamic active areas, while from the beginning of the 1990s the Global Positioning System (GPS) development also provided the opportunity to repeat geodetic measurements in geodynamic and volcanic areas. At Mt. Etna, the continuous measurements from shallow borehole tiltmeters have been successfully used to infer the mechanisms of magma accumulation and intrusive processes that foreran and accompanied the several eruptions occurring during the last thirty years on this very active volcano. The long-term deformation, associated with unrest and/or eruptive phases, is expected to be larger than tectonic deformation and therefore significant long-lived trends could be detected. For the first time, we present 25 years (1990 - 2014) of continuous borehole tilt recorded at Etna volcano at different stations and vertical displacement periodically measured by GPS. We analyze long-term series that comprise several main flank eruptions, which we believe are unique in the landscape of instrumental monitoring of geodynamic active areas. The good similarity of the patterns obtained from the two independent long-term measurements (borehole tilt and GPS) confirms the long-term stability of the borehole signals, the overall reliability of vertical GPS variations and provides robust support to the interpretation on the volcano dynamics. The tilt and GPS data series reveal that during this lengthy period, there were two primary volcanic phases: i) a major recharging in the period 1994 - 2001 that culminated with the two major explosive-effusive flank eruptions in 2001 and 2002-2003, and ii) a subsequent prolonged period of re-equilibrium that was accompanied by three other effusive flank eruptions and 44 episodes of lava fountains in 2011-2013. This highlights that, in the long-term (tens of years), a single strong recharge phase may not imply a following single main eruption, but could even

  2. Continuous increase in HIV-1 incidence after the year 2000 among men who have sex with men in Rome: insights from a 25-year retrospective cohort study.

    PubMed

    Giuliani, M; Vescio, M F; Latini, A; Palamara, G; Pimpinelli, F; Dona, M G; Stivali, F; Carduccelli, F; Ensoli, F; Di Carlo, A; Rezza, G

    2014-11-27

    To assess trends in HIV-1 incidence and risk factors for seroconversion among men who have sex with men (MSM) resident in Rome, Italy, a retrospective longitudinal cohort study was conducted over 25 years. Incidence rates and trends were modelled using Poisson regression and risk factors were assessed by multivariate Cox models. Of 1,862 HIV-1-negative individuals, 347 seroconverted during follow-up. HIV-1 incidence rates increased from 5.2/100 persons/year (p/y) in 1986 (95% confidence interval (CI): 2.3–11.5) to 9.2/00 p/y in 1992 (95% CI: 6.4–13.0), decreased to 1.3/100 p/y in 2001 and increased until 2009 (11.7/100 p/y; 95% CI: 7.4–18.6). The risk of HIV-1 seroconversion increased during the study period in younger MSM (incidence rate ratio (IRR) = 17.18; 95% CI: 9.74–30.32 in 16–32 year-olds and IRR = 5.09; 95% CI: 2.92–8.87 in 33–41 year-olds) and in those who acquired syphilis (IRR = 7.71; 95% CI: 5.00–11.88). In contrast, the risk of seroconversion decreased among highly educated MSM (IRR = 0.54; 95% CI: 0.35–0.82) and those without Italian citizenship (IRR = 0.45; 95% CI: 0.28–0.71). The HIV epidemic in MSM living in Rome continues to expand. Targeted prevention programmes against sexually transmitted infections to enhance knowledge transfer and behavioural skills are urgently required.

  3. Improving Oral Fluency, Written Accuracy, and Reading Comprehension in the 3rd Grade Using Visual Art Content.

    ERIC Educational Resources Information Center

    Nickell, Brian K.

    Students in the targeted school exhibited a decline in reading scores between second and fourth grade. Due to poor reading levels for 2 consecutive years the state put the school on a probationary list with in its district. Evidence for the existence of the problem included documented low reading test scores, below proficiency assessment records,…

  4. Assessment of Physical Activity Levels of 3rd and 4th Grade Children Using Pedometers during Physical Education Class

    ERIC Educational Resources Information Center

    Smith, John; Nichols, David; Biggerstaff, Kyle; DiMarco, Nancy

    2009-01-01

    The purpose of this study was to determine the amount of physical activity in which children engage during physical education classes and factors that mediate their participation. Third and 4th grade students wore pedometers during each 30-min physical education class for one school year. Steps per class were collected daily during structured and…

  5. Comparison of 2-Year Outcomes of Extended Criteria Cardiac Transplantation Versus Destination Left Ventricular Assist Device Therapy Using Continuous Flow.

    PubMed

    Daneshmand, Mani A; Krishnamoorthy, Arun; Samsky, Marc D; Felker, G Michael; Pura, John A; Lokhnygina, Yuliya; Hernandez, Adrian F; Rosenberg, Paul B; Blue, Laura J; Schroder, Jacob N; Rogers, Joseph G; Milano, Carmelo A; Patel, Chetan B

    2015-08-15

    Alternatives have emerged for patients ineligible for cardiac transplantation under standard criteria. The purpose of our study was to compare outcomes in patients ineligible for cardiac transplantation under standard criteria, treated either with extended criteria cardiac transplantation (ECCT) or a continuous flow destination therapy left ventricular assist device (CF DT-LVAD). From 2005 to 2012, patients treated with either ECCT or CF DT-LVAD at our institution were retrospectively analyzed. In the overall unmatched cohort, we examined mortality and other outcomes, including index hospitalization length of stay, renal function, stroke, and readmission rates. After propensity score (PS) matching, outcomes were compared between ECCT and CF DT-LVAD recipients. Overall, 62 patients underwent ECCT, and 146 patients were treated with CF DT-LVAD. The 2-year mortality estimate for ECCT recipients was 27.3% (95% confidence interval 15.5% to 39.1%) and for CF DT-LVAD recipients was 11.2% (95% confidence interval 4.8% to 17.6%). After PS matching of 39 patients from each treatment group, there was no significant difference in overall survival after 2 years (p = 0.346). In both unmatched and PS-matched analyses, CF DT-LVAD patients compared with ECCT had a significantly higher estimated glomerular filtration rate at 1 year but also had significantly higher hospital readmission rates. Stroke also more commonly occurred after CF DT-LVAD compared with ECCT (17 vs 5, unmatched; and 2 vs 1, PS matched). However, there was no significant difference between PS-matched groups in 2-year stroke-free survival (p = 0.371). In conclusion, ECCT and CF DT-LVAD in select patients are comparable therapies with respect to 2-year survival. PMID:26092273

  6. [Pathological diagnosis, work-up and reporting of breast cancer. Recommendations of the 3rd Hungarian Consensus Conference on Breast Cancer].

    PubMed

    Cserni, Gábor; Kulka, Janina; Francz, Monika; Járay, Balázs; Kálmán, Endre; Kovács, Ilona; Krenács, Tibor; Udvarhelyi, Nóra; Vass, László

    2016-09-01

    There have been relevant changes in the diagnosis and treatment of breast cancer to implement the updating of the 2010 recommendations made during the 2nd national consensus conference on the disease. Following a wide interdisciplinary consultation, the present recommendations have been finalized after their public discussion at the 3rd Hungarian Consensus Conference on Breast Cancer. The recommendations cover non-operative and intraoperative diagnostics, the work-up of operative specimens, the determination of prognostic and predictive markers and the content of the cytology and histology reports. Furthermore, it touches some special issues such as the current status of multigene molecular markers, the role of pathologists in clinical trials and prerequisites for their involvement, some relevant points about the future. PMID:27579721

  7. From challenges to solutions. European Bioanalysis Forum 3rd Annual Open Symposium, Hesperia Towers, Barcelona, Spain, 1-3 December 2010.

    PubMed

    Abbott, Richard W; Gordon, Ben; van Amsterdam, Peter; Lausecker, Berthold; Brudny-Kloeppel, Margarete; Smeraglia, John; Romero, Fernando; Globig, Susanne; Golob, Michaela; Knutsson, Magnus; Herling, Christian; Vieser, Eva; Timmerman, Philip

    2011-04-01

    The European Bioanalysis Forum is a bioanalytical nonprofit organization comprised of European pharmaceutical companies (27 members to date) and currently expanding to include CROs as well. The European Bioanalysis Forum provides a broad European bioanalytical network for the discussion of scientific, technological and regulatory topics of bioanalytical interest. The 3rd Annual Open Symposium was again much anticipated after the two previous successful meetings. The symposium included sessions on thinking outside the 'commodity' box, bioanalytical challenges with blood, global harmonization, assay platforms, dried blood spots, immunogenicity, matrix effects, anomalous results, biomarkers and two plenary technology sessions hosted by the Platinum sponsors. Experts and key opinion leaders were invited as guest speakers. A total of 424 delegates registered from 113 companies representing a large percentage of the European bioanalytical community. In addition to 48 oral presentations, 88 posters were presented and there was a vendor exposition of 40 companies.

  8. Reflections: Surgical Education-the Times they are a-Changin': Lessons Learned from the 3rd MAYMET-ESO Joint Meeting.

    PubMed

    Tarkowski, Radoslaw; Vetto, John T

    2015-09-01

    Technical skills are not sufficient for successful surgical care. Non-technical skills such as team work, decision-making in cancer treatment, communication with the patient, ethical challenges, situation awareness, and communication in the operating room are mandatory for favorable outcomes. Although formally taught in other high-demand disciplines, such skills were traditionally rarely discussed in surgical oncology. The 3rd MAYMET-ESO Joint Meeting "Professionalism for Breast Surgeons" held in Istanbul, Turkey, 5 October 2013 was dedicated to the development of non-technical skills in the everyday activity of breast surgeons. We briefly discuss information from this very interesting and inspiring educational event and how it relates to more recent changes in surgical oncology education. PMID:25903052

  9. Deuterium beam acceleration with 3rd harmonic ion cyclotron resonance heating in Joint European Torus: Sawtooth stabilization and Alfvén eigenmodes

    NASA Astrophysics Data System (ADS)

    Gassner, T.; Schoepf, K.; Sharapov, S. E.; Kiptily, V. G.; Pinches, S. D.; Hellesen, C.; Eriksson, J.; JET-EFDA contributors

    2012-03-01

    Experiments on accelerating NBI-produced deuterium (D) beam ions from their injection energy of ˜110 keV up to the MeV energy range with 3rd harmonic ion cyclotron resonance heating were performed on the Joint European Torus [P. H. Rebut and B. E. Keen, Fusion Technol. 11, 13 (1987)]. A renewed set of nuclear diagnostics was used for analysing fast D ions during sawtooth stabilization, monster sawtooth crashes, and during excitation of Alfvén eigenmodes (AEs) residing inside the q = 1 radius. The measurements and modeling of the fast ions with the nonlinear HAGIS code [S. D. Pinches et al., Comput. Phys. Commun. 111, 133 (1998)] show that monster sawtooth crashes are strongly facilitated by the AE-induced re-distribution of the fast D ions from inside the q = 1 radius to the plasma edge.

  10. Knowledge and institutional requirements to promote land degradation neutrality in drylands - An analysis of the outcomes of the 3rd UNCCD scientific conference

    NASA Astrophysics Data System (ADS)

    Akhtar-Schuster, Mariam; Safriel, Uriel; Abraham, Elena; de Vente, Joris; Essahli, Wafa; Escadafal, Richard; Stringer, Lindsay

    2015-04-01

    Achieving land degradation neutrality (LDN) through sustainable land management (SLM) targets the maintenance or restoration of the productivity of land, and therefore has to include decision-makers, knowledge generators and knowledge holders at the different relevant geographic scales. In order to enhance the implementation of the Convention, the Conference of the Parties (COP) of the United Nations Convention to Combat Desertification therefore decided that each future session of its Committee on Science and Technology (CST) would be organized in a predominantly scientific and technical conference-style format. This contribution will outline the major outcomes of UNCCD's 3rd scientific conference that will be held in Cancún, Mexico, from 9 to 12 March 2015, on addressing desertification, land degradation and drought issues (DLDD) for poverty reduction and sustainable development. The conference follows an exceptional new round table conference format that will allow the various stakeholders to discuss scientific as well as the contribution of traditional knowledge and practices in combating land degradation. This format should provide two-way communication and enable deeper insight into the availability and contribution of all forms of knowledge for achieving LDN through the assessment of: • the vulnerability of lands to DLDD and climate change and the adaptive capacities of socio-ecosystems; • best examples of adapted, knowledge-based practices and technologies; • monitoring and assessment methods to evaluate the effectiveness of adaptation practices and technologies. The outcomes of UNCCD's 3rd scientific conference will serve as a basis for discussing: • contributions of science to diagnose the status of land; • research gaps that need to be addressed to achieve LDN for poverty reduction; • additional institutional requirements to optimally bridge knowledge generation, knowledge maintenance and knowledge implementation at the science

  11. Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: key messages from Disease Control Priorities, 3rd edition.

    PubMed

    Gelband, Hellen; Sankaranarayanan, Rengaswamy; Gauvreau, Cindy L; Horton, Susan; Anderson, Benjamin O; Bray, Freddie; Cleary, James; Dare, Anna J; Denny, Lynette; Gospodarowicz, Mary K; Gupta, Sumit; Howard, Scott C; Jaffray, David A; Knaul, Felicia; Levin, Carol; Rabeneck, Linda; Rajaraman, Preetha; Sullivan, Terrence; Trimble, Edward L; Jha, Prabhat

    2016-05-21

    Investments in cancer control--prevention, detection, diagnosis, surgery, other treatment, and palliative care--are increasingly needed in low-income and particularly in middle-income countries, where most of the world's cancer deaths occur without treatment or palliation. To help countries expand locally appropriate services, Cancer (the third volume of nine in Disease Control Priorities, 3rd edition) developed an essential package of potentially cost-effective measures for countries to consider and adapt. Interventions included in the package are: prevention of tobacco-related cancer and virus-related liver and cervical cancers; diagnosis and treatment of early breast cancer, cervical cancer, and selected childhood cancers; and widespread availability of palliative care, including opioids. These interventions would cost an additional US$20 billion per year worldwide, constituting 3% of total public spending on health in low-income and middle-income countries. With implementation of an appropriately tailored package, most countries could substantially reduce suffering and premature death from cancer before 2030, with even greater improvements in later decades.

  12. Report on the 3'rd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011

    PubMed Central

    2012-01-01

    From November 4th- 6th 2011, the 3rd NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. Like in the previous years, the meeting provided an excellent platform for scientific exchange and the presentation of innovative projects for young colleagues in the fields of neurovascular research, neuroinflammation and neurodegeneration. As kick-off to the scientific sessions, Reinhard Hohlfeld, Head of the Institute for Clinical Neuroimmunology in Munich, gave an illustrious overview on the many fascinations of neuroimmunologic research. A particular highlight on the second day of the meeting was the award of the 1'st NEUROWIND e.V. prize for young academics in the field of experimental neurology. This award is posted for young colleagues under the age of 35 with a significant achievement in the field of neurovascular research, neuroinflammation or neurodegeneration and comprises an amount of 20.000 Euro, founded by Merck Serono GmbH, Darmstadt. Germany. The first prize was awarded to Ivana Nikic from Martin Kerschensteiner's group in Munich for her brilliant work on a reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis, published in Nature Medicine in 2011. This first prize award ceremony was a great incentive for the next call for proposals now upcoming in 2012. PMID:22360825

  13. Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: key messages from Disease Control Priorities, 3rd edition.

    PubMed

    Gelband, Hellen; Sankaranarayanan, Rengaswamy; Gauvreau, Cindy L; Horton, Susan; Anderson, Benjamin O; Bray, Freddie; Cleary, James; Dare, Anna J; Denny, Lynette; Gospodarowicz, Mary K; Gupta, Sumit; Howard, Scott C; Jaffray, David A; Knaul, Felicia; Levin, Carol; Rabeneck, Linda; Rajaraman, Preetha; Sullivan, Terrence; Trimble, Edward L; Jha, Prabhat

    2016-05-21

    Investments in cancer control--prevention, detection, diagnosis, surgery, other treatment, and palliative care--are increasingly needed in low-income and particularly in middle-income countries, where most of the world's cancer deaths occur without treatment or palliation. To help countries expand locally appropriate services, Cancer (the third volume of nine in Disease Control Priorities, 3rd edition) developed an essential package of potentially cost-effective measures for countries to consider and adapt. Interventions included in the package are: prevention of tobacco-related cancer and virus-related liver and cervical cancers; diagnosis and treatment of early breast cancer, cervical cancer, and selected childhood cancers; and widespread availability of palliative care, including opioids. These interventions would cost an additional US$20 billion per year worldwide, constituting 3% of total public spending on health in low-income and middle-income countries. With implementation of an appropriately tailored package, most countries could substantially reduce suffering and premature death from cancer before 2030, with even greater improvements in later decades. PMID:26578033

  14. A Guide for Parents and Families about What Your 3rd Grader Should Be Learning in School This Year. Don't Fail Your Children.

    ERIC Educational Resources Information Center

    South Carolina State Education Oversight Committee, Columbia.

    This guide shares information about the South Carolina Curriculum Standards with parents. The standards outline state requirements for children's learning, and what students across the state should be able to do in certain subjects. The guide lists seven key reasons for parents to be aware of the new curriculum standards, and then presents a…

  15. Designing Successful Transitions: A Guide for Orienting Students to College. 3rd Edition. The First-Year Experience Monograph Series No. 13

    ERIC Educational Resources Information Center

    Ward-Roof, Jeanine A., Ed.

    2010-01-01

    The 2010 edition of this monograph addresses many topics (e.g., administration of orientation programs, family involvement, student characteristics and needs, assessment, and orientation for specific student populations and institutional types) that were included in previous editions but approaches them with new information, updated data, and…

  16. [Branch of the 1st Federal Budget Institution "3rd Central Military Clinical Hospital n. a. A. A. Vishnevskiĭ of the Russian Defense Ministry"--60 years].

    PubMed

    Beznosik, R V; Savitskiĭ, G G

    2012-03-01

    The history of creation and development of the Central Tuberculosis Hospital of the Ministry of Defense of the USSR--now branch No 1 FBU "3 TsVKG of the Russian Defense Ministry n. a. A.A. Vishnevsky". The contribution into the hospital, not only in organizing of effective treatment, but also into study the state of TB control in the armed forces, the development of methods for differential diagnosis of pulmonary tuberculosis and extrapulmonary forms are presented. The incidence of tuberculosis in the country remains high, so the problem faced by the institution, remain relevant and responsible. PMID:22686035

  17. [Branch of the 1st Federal Budget Institution "3rd Central Military Clinical Hospital n. a. A. A. Vishnevskiĭ of the Russian Defense Ministry"--60 years].

    PubMed

    Beznosik, R V; Savitskiĭ, G G

    2012-03-01

    The history of creation and development of the Central Tuberculosis Hospital of the Ministry of Defense of the USSR--now branch No 1 FBU "3 TsVKG of the Russian Defense Ministry n. a. A.A. Vishnevsky". The contribution into the hospital, not only in organizing of effective treatment, but also into study the state of TB control in the armed forces, the development of methods for differential diagnosis of pulmonary tuberculosis and extrapulmonary forms are presented. The incidence of tuberculosis in the country remains high, so the problem faced by the institution, remain relevant and responsible.

  18. Year Four, 104th Congress, 3rd quarter report, January 1, 1995--March 31, 1995. DOE/KEURP Site Operator Program

    SciTech Connect

    1995-06-01

    Kansas State University is participating in the Department of Energy`s Electric Vehicle Site Operator Program. Kansas State is displaying, testing, and evaluating electric or hybrid vehicle technology. This participation will provide organizations an opportunity to examine the latest EHV prototypes under actual operating conditions.

  19. Effects of Deep Water Source-Sink Terms in 3rd generation Wave Model SWAN using different wind data in Black Sea

    NASA Astrophysics Data System (ADS)

    Kirezci, Cagil; Ozyurt Tarakcioglu, Gulizar

    2016-04-01

    Coastal development in Black Sea has increased in recent years. Therefore, careful monitoring of the storms and verification of numerical tools with reliable data has become important. Previous studies by Kirezci and Ozyurt (2015) investigated extreme events in Black Sea using different wind datasets (NCEP's CFSR and ECMWF's operational datasets) and different numerical tools (SWAN and Wavewatch III). These studies showed that significant effect to results is caused by the deep water source-sink terms (wave growth by wind, deep water dissipation of wave energy (whitecapping) and deep water non-linear wave-wave interactions). According to Timmermans(2015), uncertainty about wind forcing and the process of nonlinear wave-wave interactions are found to be dominant in numerical wave modelling. Therefore, in this study deep water source and sink term solution approaches of 3rd generation numerical tool (SWAN model) are tested, validated and compared using the selected extreme storms in Black Sea. 45 different storms and storm like events observed in Black Sea between years 1994-1999 are selected to use in the models. The storm selection depends on the instrumental wave data (significant wave heights, mean wave period and mean wave direction) obtained in NATO-TU Waves project by the deep water buoy measurements at Hopa, Sinop, Gelendzhik, and wind data (mean and peak wind speeds, storm durations) of the regarding events. 2 different wave growth by wind with the corresponding deep water dissipation terms and 3 different wave -wave interaction terms of SWAN model are used in this study. Wave growth by wind consist of two parts, linear growth which is explained by Cavaleri and Malanotte-Rizzoli(1981),and dominant exponential growth. There are two methods in SWAN model for exponential growth of wave, first one by Snyder et al. (1981), rescaled in terms of friction velocity by Komen et. al (1984) which is derived using driving wind speed at 10m elevation with related drag

  20. Effects of Deep Water Source-Sink Terms in 3rd generation Wave Model SWAN using different wind data in Black Sea

    NASA Astrophysics Data System (ADS)

    Kirezci, Cagil; Ozyurt Tarakcioglu, Gulizar

    2016-04-01

    Coastal development in Black Sea has increased in recent years. Therefore, careful monitoring of the storms and verification of numerical tools with reliable data has become important. Previous studies by Kirezci and Ozyurt (2015) investigated extreme events in Black Sea using different wind datasets (NCEP's CFSR and ECMWF's operational datasets) and different numerical tools (SWAN and Wavewatch III). These studies showed that significant effect to results is caused by the deep water source-sink terms (wave growth by wind, deep water dissipation of wave energy (whitecapping) and deep water non-linear wave-wave interactions). According to Timmermans(2015), uncertainty about wind forcing and the process of nonlinear wave-wave interactions are found to be dominant in numerical wave modelling. Therefore, in this study deep water source and sink term solution approaches of 3rd generation numerical tool (SWAN model) are tested, validated and compared using the selected extreme storms in Black Sea. 45 different storms and storm like events observed in Black Sea between years 1994-1999 are selected to use in the models. The storm selection depends on the instrumental wave data (significant wave heights, mean wave period and mean wave direction) obtained in NATO-TU Waves project by the deep water buoy measurements at Hopa, Sinop, Gelendzhik, and wind data (mean and peak wind speeds, storm durations) of the regarding events. 2 different wave growth by wind with the corresponding deep water dissipation terms and 3 different wave -wave interaction terms of SWAN model are used in this study. Wave growth by wind consist of two parts, linear growth which is explained by Cavaleri and Malanotte-Rizzoli(1981),and dominant exponential growth. There are two methods in SWAN model for exponential growth of wave, first one by Snyder et al. (1981), rescaled in terms of friction velocity by Komen et. al (1984) which is derived using driving wind speed at 10m elevation with related drag

  1. 42 years of continuous observations of the Solar 1 diameter from 1974 to 2015 - What do they forecast.

    NASA Astrophysics Data System (ADS)

    Humberto Andrei, Alexandre; Penna, Jucira; Boscardin, Sergio; Papa, Andres R. R.; Garcia, Marcos Antonio; Sigismondi, Costantino

    2016-07-01

    Heliometer has the same focal length and aperture of the earlier solar astrolabes, and the diameter determination uses the same physical and mathematical definition of the solar limb. Therefore the same robust, no-hypothesis, simple combination by an adding constant, can be used to include the Heliometer measurements along the previous long, continuous series. As a result the series of measurements of the variation of the solar diameter reaches 42 years, and covers also the solar cycle 24. In this paper we review all the individual series chief elements, as well as the calculation and values of the adding constants. We show the earlier comparison that lead to an anticorrelation at 0.867 to the solar activity record, when the 11 years modulation is expurgate, and exhibits an impressively accurate description of cycle 23. On the strength of such successful analysis we employ the new longer series to discuss the current solar cycle 24 and forecast for the following solar cycle 25. We thus advocate in favor of continued and continuous ground measurements of the solar diameter, on the usefulness of making these results available to the scientific community at large, and on the matter-of-fact, real variations of the solar diameter on long term time periods and/or local places on the Sun, in this case possibly associated to major magnetism driven solar transients.

  2. Is It Worth Continuing Sexual Rehabilitation after Radical Prostatectomy with Intracavernous Injection of Alprostadil for More than 1 Year?

    PubMed Central

    Yiou, René; Bütow, Zentia; Parisot, Juliette; Binhas, Michele; Lingombet, Odile; Augustin, Deborah; de la Taille, Alexandre; Audureau, Etienne

    2015-01-01

    Introduction Intracavernous alprostadil injection (IAI) is a widely used treatment for sexual rehabilitation (SR) after radical prostatectomy (RP). It is unknown whether the continuation of IAI beyond 1 year continues to improve erectile function. Aims To assess evolution of sexual function in patients using IAI who are nonresponsive to phosphodiesterase type 5 inhibitors (PDE5i) between 12 (M12) and 24 (M24) months after RP. Methods We retrospectively studied 75 men with a nerve-sparing laparoscopic RP, who had normal preoperative erectile function, and who regularly used IAI for SR for at least 24 months. At M12, no patients had responded to PDE5i. Main Outcome Measures At 12 and 24 months, sexual function was assessed with the UCLA Prostate Cancer Index (UCLA-PCI), International Index of Erectile Function (IIEF)-15, and erection hardness score (EHS) with and without IAI. We also assessed the satisfaction rate with IAI, injection-related penile pain, and satisfaction of treatment. Statistical analysis was performed by using t-tests for paired data and Spearman's rho correlation coefficients to assess the relationships between scores at M12 and M24. Results Improvement of nocturnal erection was noted (UCLA-PCI, question 25); however, no significant difference was found for IIEF-erectile function with (19.60 ± 9.80 vs. 18.07 ± 10.44) and without IAI (4.63 ± 2.93 vs. 4.92 ± 4.15), UCLA-PCI-sexual bother (37.14 ± 21.45 vs. 37.54 ± 19.67), nor the EHS score with (2.97 ± 1.30 vs. 2.57 ± 1.30) and without IAI (0.67 ± 1.11 vs. 0.76 ± 0.10). The rate of satisfaction with treatment decreased over time (66.6% vs. 46.7%, P = 0.013). Improved response to IAI at M12 was not correlated to improvement in spontaneous erections at M24. Conclusion The response to IAI remained stable after 2 years of treatment, and no significant improvement of spontaneous erections during intercourse attempts was found between M12 and M24

  3. Strain accumulation in the New Madrid and Wabash Valley seismic zones from 14 years of continuous GPS observation

    NASA Astrophysics Data System (ADS)

    Craig, Timothy J.; Calais, Eric

    2014-12-01

    The mechanical behavior—and hence earthquake potential—of faults in continental interiors is an issue of critical importance for the resultant seismic hazard, but no consensus has yet been reached on this controversial topic. The debate has focused on the central and eastern United States, in particular, the New Madrid Seismic Zone, struck by four magnitude 7 or greater earthquakes in 1811-1812, and to a lesser extent the Wabash Valley Seismic Zone just to the north. A key aspect of this issue is the rate at which strain is currently accruing on those plate interior faults, a quantity that remains debated. Here we address this issue with an analysis of up to 14.6 years of continuous GPS data from a network of 200 sites in the central United States centered on the New Madrid and Wabash Valley seismic zones. We find that the high-quality sites in these regions show motions that are consistently within the 95% confidence limit of zero deformation. These results place an upper bound on strain accrual on faults of 0.2 mm/yr and 0.6 mm/yr in the New Madrid and Wabash Valley Seismic Zones, respectively. For the New Madrid region, where a paleoseismic record is available for the past ˜5000 years, we argue that strain accrual—if any—does not permit the 500-900 year repeat time of paleo-earthquakes observed in the Upper Mississippi Embayment. These results, together with increasing evidence for temporal clustering and spatial migration of earthquake sequences in continental interiors, indicate that either tectonic loading rates or fault properties vary with time in the New Madrid Seismic Zone and possibly plate wide.

  4. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.

    PubMed

    Patel, Vikram; Chisholm, Dan; Parikh, Rachana; Charlson, Fiona J; Degenhardt, Louisa; Dua, Tarun; Ferrari, Alize J; Hyman, Steve; Laxminarayan, Ramanan; Levin, Carol; Lund, Crick; Medina Mora, María Elena; Petersen, Inge; Scott, James; Shidhaye, Rahul; Vijayakumar, Lakshmi; Thornicroft, Graham; Whiteford, Harvey

    2016-04-16

    The burden of mental, neurological, and substance use (MNS) disorders increased by 41% between 1990 and 2010 and now accounts for one in every 10 lost years of health globally. This sobering statistic does not take into account the substantial excess mortality associated with these disorders or the social and economic consequences of MNS disorders on affected persons, their caregivers, and society. A wide variety of effective interventions, including drugs, psychological treatments, and social interventions, can prevent and treat MNS disorders. At the population-level platform of service delivery, best practices include legislative measures to restrict access to means of self-harm or suicide and to reduce the availability of and demand for alcohol. At the community-level platform, best practices include life-skills training in schools to build social and emotional competencies. At the health-care-level platform, we identify three delivery channels. Two of these delivery channels are especially relevant from a public health perspective: self-management (eg, web-based psychological therapy for depression and anxiety disorders) and primary care and community outreach (eg, non-specialist health worker delivering psychological and pharmacological management of selected disorders). The third delivery channel, hospital care, which includes specialist services for MNS disorders and first-level hospitals providing other types of services (such as general medicine, HIV, or paediatric care), play an important part for a smaller proportion of cases with severe, refractory, or emergency presentations and for the integration of mental health care in other health-care channels, respectively. The costs of providing a significantly scaled up package of specified cost-effective interventions for prioritised MNS disorders in low-income and lower-middle-income countries is estimated at US$3-4 per head of population per year. Since a substantial proportion of MNS disorders run a

  5. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.

    PubMed

    Patel, Vikram; Chisholm, Dan; Parikh, Rachana; Charlson, Fiona J; Degenhardt, Louisa; Dua, Tarun; Ferrari, Alize J; Hyman, Steve; Laxminarayan, Ramanan; Levin, Carol; Lund, Crick; Medina Mora, María Elena; Petersen, Inge; Scott, James; Shidhaye, Rahul; Vijayakumar, Lakshmi; Thornicroft, Graham; Whiteford, Harvey

    2016-04-16

    The burden of mental, neurological, and substance use (MNS) disorders increased by 41% between 1990 and 2010 and now accounts for one in every 10 lost years of health globally. This sobering statistic does not take into account the substantial excess mortality associated with these disorders or the social and economic consequences of MNS disorders on affected persons, their caregivers, and society. A wide variety of effective interventions, including drugs, psychological treatments, and social interventions, can prevent and treat MNS disorders. At the population-level platform of service delivery, best practices include legislative measures to restrict access to means of self-harm or suicide and to reduce the availability of and demand for alcohol. At the community-level platform, best practices include life-skills training in schools to build social and emotional competencies. At the health-care-level platform, we identify three delivery channels. Two of these delivery channels are especially relevant from a public health perspective: self-management (eg, web-based psychological therapy for depression and anxiety disorders) and primary care and community outreach (eg, non-specialist health worker delivering psychological and pharmacological management of selected disorders). The third delivery channel, hospital care, which includes specialist services for MNS disorders and first-level hospitals providing other types of services (such as general medicine, HIV, or paediatric care), play an important part for a smaller proportion of cases with severe, refractory, or emergency presentations and for the integration of mental health care in other health-care channels, respectively. The costs of providing a significantly scaled up package of specified cost-effective interventions for prioritised MNS disorders in low-income and lower-middle-income countries is estimated at US$3-4 per head of population per year. Since a substantial proportion of MNS disorders run a

  6. Mentoring Literacy Professionals: Continuing the Spirit of CRA/ALER after 50 Years. The Thirty-First Yearbook: A Doubled Peer Reviewed Publication of the College Reading Association

    ERIC Educational Resources Information Center

    Szabo, Susan, Ed.; Sampson, Mary Beth, Ed.; Foote, Martha M., Ed.; Falk-Ross, Francine, Ed.

    2010-01-01

    This volume is a milestone year for the Yearbook, the conference, and the College Reading Association (CRA). At this conference, CRA celebrated its 50th year. The title of this thirty-first yearbook mirrors the theme of the 2008 conference--"Mentoring Literacy Professionals for 50 Years." The title "Mentoring Literacy Professionals: Continuing the…

  7. Evaluation of 4 years of continuous δ13C(CO2) data using a moving Keeling plot method

    NASA Astrophysics Data System (ADS)

    Vardag, Sanam Noreen; Hammer, Samuel; Levin, Ingeborg

    2016-07-01

    Different carbon dioxide (CO2) emitters can be distinguished by their carbon isotope ratios. Therefore measurements of atmospheric δ13C(CO2) and CO2 concentration contain information on the CO2 source mix in the catchment area of an atmospheric measurement site. This information may be illustratively presented as the mean isotopic source signature. Recently an increasing number of continuous measurements of δ13C(CO2) and CO2 have become available, opening the door to the quantification of CO2 shares from different sources at high temporal resolution. Here, we present a method to compute the CO2 source signature (δS) continuously and evaluate our result using model data from the Stochastic Time-Inverted Lagrangian Transport model. Only when we restrict the analysis to situations which fulfill the basic assumptions of the Keeling plot method does our approach provide correct results with minimal biases in δS. On average, this bias is 0.2 ‰ with an interquartile range of about 1.2 ‰ for hourly model data. As a consequence of applying the required strict filter criteria, 85 % of the data points - mainly daytime values - need to be discarded. Applying the method to a 4-year dataset of CO2 and δ13C(CO2) measured in Heidelberg, Germany, yields a distinct seasonal cycle of δS. Disentangling this seasonal source signature into shares of source components is, however, only possible if the isotopic end members of these sources - i.e., the biosphere, δbio, and the fuel mix, δF - are known. From the mean source signature record in 2012, δbio could be reliably estimated only for summer to (-25.0 ± 1.0) ‰ and δF only for winter to (-32.5 ± 2.5) ‰. As the isotopic end members δbio and δF were shown to change over the season, no year-round estimation of the fossil fuel or biosphere share is possible from the measured mean source signature record without additional information from emission inventories or other tracer measurements.

  8. A Kinesthetic Learning Approach to Earth Science for 3rd and 4th Grade Students on the Pajarito Plateau, Los Alamos, NM

    NASA Astrophysics Data System (ADS)

    Wershow, H. N.; Green, M.; Stocker, A.; Staires, D.

    2010-12-01

    Current efforts towards Earth Science literacy in New Mexico are guided by the New Mexico Science Benchmarks [1]. We are geoscience professionals in Los Alamos, NM who believe there is an important role for non-traditional educators utilizing innovative teaching methods. We propose to further Earth Science literacy for local 3rd and 4th grade students using a kinesthetic learning approach, with the goal of fostering an interactive relationship between the students and their geologic environment. We will be working in partnership with the Pajarito Environmental Education Center (PEEC), which teaches the natural heritage of the Pajarito Plateau to 3rd and 4th grade students from the surrounding area, as well as the Family YMCA’s Adventure Programs Director. The Pajarito Plateau provides a remarkable geologic classroom because minimal structural features complicate the stratigraphy and dramatic volcanic and erosional processes are plainly on display and easily accessible. Our methodology consists of two approaches. First, we will build an interpretive display of the local geology at PEEC that will highlight prominent rock formations and geologic processes seen on a daily basis. It will include a simplified stratigraphic section with field specimens and a map linked to each specimen’s location to encourage further exploration. Second, we will develop and implement a kinesthetic curriculum for an exploratory field class. Active engagement with geologic phenomena will take place in many forms, such as a scavenger hunt for precipitated crystals in the vesicles of basalt flows and a search for progressively smaller rhyodacite clasts scattered along an actively eroding canyon. We believe students will be more receptive to origin explanations when they possess a piece of the story. Students will be provided with field books to make drawings of geologic features. This will encourage independent assessment of phenomena and introduce the skill of scientific observation. We

  9. Prognosis and Continuity of Child Mental Health Problems from Preschool to Primary School: Results of a Four-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Beyer, Thomas; Postert, Christian; Muller, Jorg M.; Furniss, Tilman

    2012-01-01

    In a four-year longitudinal study, changes in and continuity of behavioral and emotional problems were examined in 814 subjects from kindergarten to primary school. Mental health problems were assessed by means of the Child Behavior Checklist (CBCL). The distribution of the CBCL broadband groups revealed a high level of continuity of internalizing…

  10. 43 CFR 3207.12 - What work am I required to perform each year for BLM to continue the initial and additional...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... year for BLM to continue the initial and additional extensions of the primary term of my lease? 3207.12... MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Lease Terms and... additional extensions of the primary term of my lease? (a) To continue the initial extension of the...

  11. 43 CFR 3207.12 - What work am I required to perform each year for BLM to continue the initial and additional...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... year for BLM to continue the initial and additional extensions of the primary term of my lease? 3207.12... MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Lease Terms and... additional extensions of the primary term of my lease? (a) To continue the initial extension of the...

  12. 43 CFR 3207.12 - What work am I required to perform each year for BLM to continue the initial and additional...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... year for BLM to continue the initial and additional extensions of the primary term of my lease? 3207.12... MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Lease Terms and... additional extensions of the primary term of my lease? (a) To continue the initial extension of the...

  13. 43 CFR 3207.12 - What work am I required to perform each year for BLM to continue the initial and additional...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... year for BLM to continue the initial and additional extensions of the primary term of my lease? 3207.12... MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCE LEASING Lease Terms and... additional extensions of the primary term of my lease? (a) To continue the initial extension of the...

  14. 10+ years of ACORK: Continuous pore pressure record from the decollement zone at Nankai Trough off Muroto

    NASA Astrophysics Data System (ADS)

    Kinoshita, M.; Davis, E. E.; Becker, K.; Miyazaki, J.; Hulme, S.; Mendrum, R.; Toki, T.; Wheat, C. G.; Kasaya, T.

    2012-12-01

    Pore pressure and hydrological properties play key roles in governing coupling and slip behavior along the subducting plate interface. During the KR22-12 cruise, three dives were completed using ROV KAIKO onboard R/V KAIREI during Dec. 20-25, 2011, to retrieve pore pressure data and interstitial fluid samples from ACORKs at ODP Holes 808I and 1173B situated landward and seaward of the deformation front in the Nankai Trough off Cape Muroto. With 3-year-long and a 4-year-long new data records from Holes 808I and 1173B, respectively, we now have over 10-year-long continuous pressure records since June 2001 at both sites. Data from most monitoring depths show systematic variations in average pressure, and in formation pressure response to seafloor tidal loading. In 2005 and 2009, we observed significant decrease in the amplitudes of pressure response to semi-diurnal tidal loading at Hole 808I. Transient changes were observed at the time of several nearby earthquakes, including the 2011 Mar. 11 Tohoku earthquake, followed by long-lasting pressure changes in both holes starting on Mar. 23, 2011. Gas-tight fluid sampling operations were successfully carried out from the hydraulic port attached to the swellable packer inserted within the ACORK head at Hole 808I. The swellable packer was set in order to isolate the décollement zone that lies roughly 20 m below the bottom of casing at 922 m below the seafloor. We observed shimmering water venting through the port, and the flow rate was measured using a ball-type flowmeter. Fluid samples looked muddy, probably as a result of staining from the casing steel. We believe that the packer seal at the ACORK head is set properly, although the pore pressure at 922 m does not seem to have increased up to 2011. Still, the observed fluid seepage suggests a significant amount of fluid evacuated from the décollement zone since ACORK installation, which may have changed its hydrogeological condition.

  15. Veterinary Microbiology, 3rd Edition

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Veterinary Microbiology, Third Edition is organized into four sections and begins with an updated and expanded introductory section on infectious disease pathogenesis, diagnosis and clinical management. The second section covers bacterial and fungal pathogens, and the third section describes viral d...

  16. Stable Isotope and Trace Element Studies on Gladiators and Contemporary Romans from Ephesus (Turkey, 2nd and 3rd Ct. AD) - Implications for Differences in Diet

    PubMed Central

    Lösch, Sandra; Moghaddam, Negahnaz; Grossschmidt, Karl; Risser, Daniele U.; Kanz, Fabian

    2014-01-01

    The gladiator cemetery discovered in Ephesus (Turkey) in 1993 dates to the 2nd and 3rd century AD. The aim of this study is to reconstruct diverse diet, social stratification, and migration of the inhabitants of Roman Ephesus and the distinct group of gladiators. Stable carbon, nitrogen, and sulphur isotope analysis were applied, and inorganic bone elements (strontium, calcium) were determined. In total, 53 individuals, including 22 gladiators, were analysed. All individuals consumed C3 plants like wheat and barley as staple food. A few individuals show indication of consumption of C4 plants. The δ13C values of one female from the gladiator cemetery and one gladiator differ from all other individuals. Their δ34S values indicate that they probably migrated from another geographical region or consumed different foods. The δ15N values are relatively low in comparison to other sites from Roman times. A probable cause for the depletion of 15N in Ephesus could be the frequent consumption of legumes. The Sr/Ca-ratios of the gladiators were significantly higher than the values of the contemporary Roman inhabitants. Since the Sr/Ca-ratio reflects the main Ca-supplier in the diet, the elevated values of the gladiators might suggest a frequent use of a plant ash beverage, as mentioned in ancient texts. PMID:25333366

  17. Oxidation of methanol on 2nd and 3rd row group VIII transition metals (Pt, Ir, Os, Pd, Rh, and Ru): Application to direct methanol fuel cells

    SciTech Connect

    Kua, J.; Goddard, W.A. III

    1999-12-01

    Using first principles quantum mechanics [nonlocal density functional theory (B3LYP)], the authors calculated the 13 most likely intermediate species for methanol oxidation on clusters of all 2nd and 3rd row Group VIII transition metals for all three likely binding sites (top, bridge, and cap). This comprehensive set of binding energies and structures allows a detailed analysis of possible reaction mechanisms and how they change for different metals. This illustrates the role in which modern quantum chemical methods can be used to provide data for combinatorial strategies for discovering and designing new catalysts. Methanol dehydrogenation is most facile on Pt, with the hydrogens preferentially stripped off the carbon end. However, water dehydrogenation is most facile on Ru. These results support the bifunctional mechanism for methanol oxidation on Pt-Ru alloys in direct methanol fuel cells (DMFCs). Pure Os is capable of performing both functionalities without cocatalyst. It is suggested that pure Os be examined as a potential catalyst for low overpotential, highly dispersed catalyst DMFCs. Pathways to form the second C-O bond differ between the pure metals (Pt and Os) in which (CO){sub ads} is probably activated by (OH){sub ads} and the Pt-Ru binary system in which (COH){sub ads} is probably activated by O{sub ads}. For all cases formation of (COOH){sub ads} is an important precursor to the final dehydrogenation to desorb CO{sub 2} from the surface.

  18. CO2 over the past 5 million years: Continuous simulation and new δ11B-based proxy data

    NASA Astrophysics Data System (ADS)

    Stap, Lennert B.; de Boer, Bas; Ziegler, Martin; Bintanja, Richard; Lourens, Lucas J.; van de Wal, Roderik S. W.

    2016-04-01

    During the past five million yrs, benthic δ18O records indicate a large range of climates, from warmer than today during the Pliocene Warm Period to considerably colder during glacials. Antarctic ice cores have revealed Pleistocene glacial-interglacial CO2 variability of 60-100 ppm, while sea level fluctuations of typically 125 m are documented by proxy data. However, in the pre-ice core period, CO2 and sea level proxy data are scarce and there is disagreement between different proxies and different records of the same proxy. This hampers comprehensive understanding of the long-term relations between CO2, sea level and climate. Here, we drive a coupled climate-ice sheet model over the past five million years, inversely forced by a stacked benthic δ18O record. We obtain continuous simulations of benthic δ18O, sea level and CO2 that are mutually consistent. Our model shows CO2 concentrations of 300 to 470 ppm during the Early Pliocene. Furthermore, we simulate strong CO2 variability during the Pliocene and Early Pleistocene. These features are broadly supported by existing and new δ11B-based proxy CO2 data, but less by alkenone-based records. The simulated concentrations and variations therein are larger than expected from global mean temperature changes. Our findings thus suggest a smaller Earth System Sensitivity than previously thought. This is explained by a more restricted role of land ice variability in the Pliocene. The largest uncertainty in our simulation arises from the mass balance formulation of East Antarctica, which governs the variability in sea level, but only modestly affects the modeled CO2 concentrations.

  19. Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity.

    PubMed

    Lyons, Robert P; Scholz, Christopher A; Cohen, Andrew S; King, John W; Brown, Erik T; Ivory, Sarah J; Johnson, Thomas C; Deino, Alan L; Reinthal, Peter N; McGlue, Michael M; Blome, Margaret W

    2015-12-22

    The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9-15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world's largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species. PMID:26644580

  20. Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity.

    PubMed

    Lyons, Robert P; Scholz, Christopher A; Cohen, Andrew S; King, John W; Brown, Erik T; Ivory, Sarah J; Johnson, Thomas C; Deino, Alan L; Reinthal, Peter N; McGlue, Michael M; Blome, Margaret W

    2015-12-22

    The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9-15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world's largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species.

  1. The cost of postgraduate medical education and continuing medical education: re-examining the status fifty years back.

    PubMed

    Walsh, Kieran

    2015-03-01

    The subject of the cost and value of medical education is becoming increasingly important. However, this subject is not a new one. Fifty years ago, Mr. DH Patey, Dr. OF Davies, and Dr. John Ellis published a report on the state of postgraduate medical education in the UK. The report was wide-ranging, but it made a considerable mention of cost. In this short article, I have presented the documentary research that I conducted on their report. I have analyzed it from a positivist perspective and have concentrated on the subject of cost, as it appears in their report. The authors describe reforms within postgraduate medical education; however, they are clear from the start that the issue of cost can often be a barrier to such reforms. They state the need for basic facilities for medical education, but then outline the financial barriers to their development. The authors then discuss the costs of library services for education. They state that the "annual spending on libraries varies considerably throughout the country." The authors also describe the educational experiences of newly graduated doctors. According to them, the main problem is that these doctors do not have time to attend formal educational events, and that this will not be possible until there is "a more graduated approach to responsible clinical work," something which is not possible without financial investment. While concluding their report, the authors state that the limited money invested in postgraduate medical education and continuing medical education has been well spent, and that this has had a dual effect on improving medical education as well as the standards of medical care.

  2. Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity

    PubMed Central

    Lyons, Robert P.; Scholz, Christopher A.; Cohen, Andrew S.; King, John W.; Brown, Erik T.; Ivory, Sarah J.; Johnson, Thomas C.; Deino, Alan L.; Reinthal, Peter N.; McGlue, Michael M.; Blome, Margaret W.

    2015-01-01

    The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9–15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world’s largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species. PMID:26644580

  3. Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity

    NASA Astrophysics Data System (ADS)

    Lyons, Robert P.; Scholz, Christopher A.; Cohen, Andrew S.; King, John W.; Brown, Erik T.; Ivory, Sarah J.; Johnson, Thomas C.; Deino, Alan L.; Reinthal, Peter N.; McGlue, Michael M.; Blome, Margaret W.

    2015-12-01

    The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9-15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world's largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species.

  4. The Cost of Postgraduate Medical Education and Continuing Medical Education: Re-Examining the Status Fifty Years Back

    PubMed Central

    2015-01-01

    The subject of the cost and value of medical education is becoming increasingly important. However, this subject is not a new one. Fifty years ago, Mr. DH Patey, Dr. OF Davies, and Dr. John Ellis published a report on the state of postgraduate medical education in the UK. The report was wide-ranging, but it made a considerable mention of cost. In this short article, I have presented the documentary research that I conducted on their report. I have analyzed it from a positivist perspective and have concentrated on the subject of cost, as it appears in their report. The authors describe reforms within postgraduate medical education; however, they are clear from the start that the issue of cost can often be a barrier to such reforms. They state the need for basic facilities for medical education, but then outline the financial barriers to their development. The authors then discuss the costs of library services for education. They state that the "annual spending on libraries varies considerably throughout the country." The authors also describe the educational experiences of newly graduated doctors. According to them, the main problem is that these doctors do not have time to attend formal educational events, and that this will not be possible until there is "a more graduated approach to responsible clinical work," something which is not possible without financial investment. While concluding their report, the authors state that the limited money invested in postgraduate medical education and continuing medical education has been well spent, and that this has had a dual effect on improving medical education as well as the standards of medical care. PMID:25802685

  5. Metabolic engineering of E.coli for the production of a precursor to artemisinin, an anti-malarial drug [Chapter 25 in Manual of Industrial Microbiology and Biotechnology, 3rd edition

    SciTech Connect

    Petzold, Christopher; Keasling, Jay

    2011-07-18

    This document is Chapter 25 in the Manual of Industrial Microbiology and Biotechnology, 3rd edition. Topics covered include: Incorporation of Amorpha-4,11-Diene Biosynthetic Pathway into E. coli; Amorpha-4,11-Diene Pathway Optimization; "-Omics" Analyses for Increased Amorpha-4,11-Diene Production; Biosynthetic Oxidation of Amorpha-4,11-Diene.

  6. The Johnson School Study: Status of the Continuous Progress Program of Reading at Johnson Elementary School After One Year of Implementation (Fall 1974 - Spring 1975). Technical Report.

    ERIC Educational Resources Information Center

    Yonke, Annette; Olsen, George E.

    This study reports the results of a year long investigation conducted by the Research and Development Center of Roosevelt University, College of Education. The study was designed as an inquiry into the first year of a school system's attempt to implement a program of continuous progress for inner-city elementary school students in the city of…

  7. The Professional Identity of Early Years Educators in England: Implications for a Transformative Approach to Continuing Professional Development

    ERIC Educational Resources Information Center

    Lightfoot, Sarah; Frost, David

    2015-01-01

    This article examines the professional identity of nine early years educators currently working in the early years sector of education in England. These educators include teachers, teaching assistants, nursery practitioners and nursery nurses working with children three to five years old in the Early Years Foundation Stage in state-maintained…

  8. Analysis of aerosol optical properties from continuous sun-sky radiometer measurements at Halley and Rothera, Antarctica over seven years

    NASA Astrophysics Data System (ADS)

    Campanelli, Monica; Estellés, Victor; Colwell, Steve; Shanklin, Jonathan; Ningombam, Shantikumar S.

    2015-04-01

    The Antarctic continent is located far from most anthropogenic emission sources on the planet, it has limited areas of exposed rock and human activities are less developed. Air circulation over Antarctica also seems to prevent the direct transport of air originating from anthropogenic sources of pollution at lower latitudes. Therefore Antarctica is considered an attractive site for studying aerosol properties as unaltered as possible by human activity. Long term monitoring of the optical and physical properties is necessary for observing possible changes in the atmosphere over time and understanding if such changes are due to human activity or natural variation. Columnar aerosol optical and physical properties can be obtained from sun-sky radiometers, very compact instruments measuring spectral direct and diffuse solar irradiance at the visible wavelengths and using fast and efficient inversion algorithms. The British Antarctic Survey has continuously operated two Prede Pom-01 sun-sky radiometers in Antarctica as part of the ESR-European Skynet Radiometers network (www.euroskyrad.net, Campanelli et al, 2012). They are located at Halley and Rothera, and have operated since 2009 and 2008 respectively. In the present study the aerosol optical thickness, single scattering albedo, Ångström exponent, volume size distribution and refractive index were retrieved from cloud-screened measurements of direct and diffuse solar irradiance using the Skyrad 4.2 pack code (Nakajima et al., 1986). The analysis of the daily and yearly averages showed an important increase of the absorbing properties of particles at Halley from 2013 to the beginning of 2014 related to the increasing presence of smaller particles (from 2012) but with a non-significant variation of aerosol optical depth. The same increase of absorption was visible at Rothera only in 2013. Air pressure measurements, wind directions and intensity, and vertical profiles from radio-soundings, together with HYSPLIT model

  9. A novel amperometric alcohol biosensor developed in a 3rd generation bioelectrode platform using peroxidase coupled ferrocene activated alcohol oxidase as biorecognition system.

    PubMed

    Chinnadayyala, Somasekhar R; Kakoti, Ankana; Santhosh, Mallesh; Goswami, Pranab

    2014-05-15

    Alcohol oxidase (AOx) with a two-fold increase in efficiency (Kcat/Km) was achieved by physical entrapment of the activator ferrocene in the protein matrix through a simple microwave based partial unfolding technique and was used to develop a 3rd generation biosensor for improved detection of alcohol in liquid samples. The ferrocene molecules were stably entrapped in the AOx protein matrix in a molar ratio of ~3:1 through electrostatic interaction with the Trp residues involved in the functional activity of the enzyme as demonstrated by advanced analytical techniques. The sensor was fabricated by immobilizing ferrocene entrapped alcohol oxidase (FcAOx) and sol-gel chitosan film coated horseradish peroxidase (HRP) on a multi-walled carbon nanotube (MWCNT) modified glassy carbon electrode through layer-by-layer technique. The bioelectrode reactions involved the formation of H2O2 by FcAOx biocatalysis of substrate alcohol followed by HRP-catalyzed reduction of the liberated H2O2 through MWCNT supported direct electron transfer mechanism. The amperometric biosensor exhibited a linear response to alcohol in the range of 5.0 × 10(-6) to 30 × 10(-4)mol L(-1) with a detection limit of 2.3 × 10(-6) mol L(-1), and a sensitivity of 150 µA mM(-1) cm(-2). The biosensor response was steady for 28 successive measurements completed in a period of 5h and retained ~90% of the original response even after four weeks when stored at 4 °C. The biosensor was successfully applied for the determination of alcohol in commercial samples and its performance was validated by comparing with the data obtained by GC analyses of the samples.

  10. Non-destructive measurement of demineralization and remineralization in the occlusal pits and fissures of extracted 3rd molars with PS-OCT

    NASA Astrophysics Data System (ADS)

    Lee, Chulsung; Hsu, Dennis J.; Le, Michael H.; Darling, Cynthia L.; Fried, Daniel

    2009-02-01

    Previous studies have demonstrated that Polarization Sensitive Optical Coherence Tomography (PS-OCT) can be used to image the remineralization of early artificial caries lesion on smooth enamel surfaces of human and bovine teeth. However, most new dental decay is found in the pits and fissures of the occlusal surfaces of posterior dentition and it is in these high risk areas where the performance of new caries imaging devices need to be investigated. The purpose of this study was to demonstrate that PS-OCT can be used to measure the subsequent remineralization of artificial lesions produced in the pits and fissures of extracted 3rd molars. A PS-OCT system operating at 1310-nm was used to acquire polarization resolved images of occlusal surfaces exposed to a demineralizing solution at pH-4.5 followed by a fluoride containing remineralizing solution at pH-7.0 containing 2-ppm fluoride. The integrated reflectivity was calculated to a depth of 200-µm in the entire lesion area using an automated image processing algorithm. Although a well-defined surface zone was clearly resolved in only a few of the samples that underwent remineralization, the PS-OCT measurements indicated a significant (p<0.05) reduction in the integrated reflectivity between the severity of the lesions that were exposed to the remineralization solution and those that were not. The lesion depth and mineral loss were also measured with polarized light microscopy and transverse microradiography after sectioning the teeth. These results show that PS-OCT can be used to non-destructively monitor the remineralization potential of anti-caries agents in the important pits and fissures of the occlusal surface.

  11. A psychometric study of the Bayley Scales of Infant and Toddler Development - 3rd Edition for term and preterm Taiwanese infants.

    PubMed

    Yu, Yen-Ting; Hsieh, Wu-Shiun; Hsu, Chyong-Hsin; Chen, Li-Chiou; Lee, Wang-Tso; Chiu, Nan-Chang; Wu, Ying-Chin; Jeng, Suh-Fang

    2013-11-01

    The Bayley Scales of Infant and Toddler Development - 3rd Edition (Bayley-III) was updated to enhance its usefulness for contemporary child developmental assessment. However, recent data in Western countries have implicated the overestimation of child development by the new instrument. This study aimed to investigate the psychometric features of the Bayley-III for term and preterm infants in Taiwan. Forty-seven term infants and 167 preterm infants were prospectively examined with the Bayley Scales of Infant Development - 2nd Edition (BSID-II) and the Bayley-III at 6, 12, 18, and 24 months of age (corrected for prematurity). The psychometric properties examined included reliability, construct validity, and known-group validity. The intra- and inter-rater reliabilities of the Bayley-III were good to excellent. The correlations between the BSID-II and Bayley-III raw scores were good to excellent for the cognitive and motor items and low to excellent for the language items. Term infants achieved higher composite scores than preterm infants on all of the Bayley-III scales (p<0.05). However, their rates of developmental delay were lower than the previously established prevalence estimates. The Bayley-III cut-off composite score was adjusted 10-20, 1-13, and 12-24 points higher than 70 for optimal prediction of cognitive, language, and motor delay, respectively, as defined by the BSID-II index score<70. The Bayley-III is a reliable instrument that extends its previous edition, especially in early language assessment. However, the upward adjustment of its cut-off score is recommended for the accurate identification of developmental delay in term and preterm Taiwanese infants. PMID:24029804

  12. 2006 National Survey of First-Year Seminars: Continuing Innovations in the Collegiate Curriculum. The First-Year Experience Monograph Series No. 51

    ERIC Educational Resources Information Center

    Tobolowsky, Barbara F.

    2008-01-01

    Since 1988, the National Resource Center has conducted a national survey every three years to gather information about the nature and extent of first-year seminars on American college campuses. The findings from the 2006 survey administration have been reorganized to make it easier to find information of interest with major chapters focusing on…

  13. Early Intervention to Support the Academic Recovery of First-Year Students at Risk of Non-Continuation

    ERIC Educational Resources Information Center

    Lizzio, Alf; Wilson, Keithia

    2013-01-01

    The widening participation agenda and related concerns about student retention require a more systematic focus on supporting student success. This paper describes a process designed with the dual goals of supporting the short-term academic recovery of students at risk of non-continuation due to early difficulties with assessment and developing…

  14. Noun and Verb Production in Maternal and Child Language: Continuity, Stability, and Prediction across the Second Year of Life

    ERIC Educational Resources Information Center

    Longobardi, Emiddia; Spataro, Pietro; Putnick, Diane L.; Bornstein, Marc H.

    2016-01-01

    The present study examined continuity/discontinuity and stability/instability of noun and verb production measures in 30 child-mother dyads observed at 16 and 20 months, and predictive relations with the acquisition of nouns and verbs at 24 months. Children exhibited significant discontinuity and robust stability in the frequency of nouns and…

  15. Where's the Other "C"? Year 9 Examine Continuity in the Treatment of Mental Health through Time

    ERIC Educational Resources Information Center

    Murray, Helen; Burney, Rachel; Stacey-Chapman, Andrew

    2013-01-01

    Helen Murray, Rachel Burney and Andrew Stacey-Chapman show how they strengthened three goals of their practice--secure knowledge, narrative shapes and conceptual analysis--by securing strong connection between them. The curricular focus that drew all this together was "historical continuity", a property crucial to narrative, but often…

  16. The Continuity of College Students' Autonomous Learning Motivation and Its Predictors: A Three-Year Longitudinal Study

    ERIC Educational Resources Information Center

    Pan, Yingqiu; Gauvain, Mary

    2012-01-01

    This study examined change in Chinese students' autonomous learning motivation in the first three years of college and how this change is accounted for by intra- and inter-individual variables. The sample included 633 (328 female) college freshmen. Results showed that students' autonomous learning motivation decreased over years in college.…

  17. Odanacatib in the treatment of postmenopausal women with low bone mineral density: five years of continued therapy in a phase 2 study.

    PubMed

    Langdahl, Bente; Binkley, Neil; Bone, Henry; Gilchrist, Nigel; Resch, Heinrich; Rodriguez Portales, Jose; Denker, Andrew; Lombardi, Antonio; Le Bailly De Tilleghem, Celine; Dasilva, Carolyn; Rosenberg, Elizabeth; Leung, Albert

    2012-11-01

    Odanacatib (ODN) is a selective inhibitor of the collagenase cathepsin K that is highly expressed by osteoclasts. In this 2-year, phase 2, dose-ranging trial, postmenopausal women with bone mineral density (BMD) T-scores -2.0 to -3.5 at spine or hip were randomized to weekly placebo or ODN 3, 10, 25, or 50 mg plus vitamin D(3) and calcium. Prespecified trial-extensions continued through 5 years. In year 3, all women were re-randomized to ODN 50 mg or placebo. For years 4 and 5, women who received placebo or ODN 3 mg in years 1 and 2 and placebo in year 3 received ODN 50 mg; others continued year 3 treatments. Endpoints included lumbar spine (primary), hip, 1/3 radius, and total body BMD; markers of bone metabolism; and safety. Women in the year 4 to 5 extension receiving placebo (n = 41) or ODN 50 mg (n = 100) had similar baseline characteristics. For women who received ODN (10-50 mg) for 5 years, spine and hip BMD increased over time. With ODN 50 mg continually for 5 years (n = 13), mean lumbar spine BMD percent change from baseline (95% confidence interval [CI]) was 11.9% (7.2% to 16.5%) versus -0.4% (-3.1% to 2.3%) for women who were switched from ODN 50 mg to placebo after 2 years (n = 14). In pooled results of women receiving continuous ODN (10-50 mg, n = 26-29), year 5 geometric mean percent changes from baseline in bone resorption markers cross-linked N-telopeptide of type I collagen (NTX)/creatinine and cross-linked C-telopeptide (CTX) were approximately -55%, but near baseline for bone formation markers bone-specific alkaline phosphatase (BSAP) and amino-terminal propeptide of type I procollagen (P1NP). In women switched from ODN 10 to 50 mg to placebo after 2 years (n = 25), bone turnover markers were near baseline. In summary, women receiving combinations of ODN (10-50 mg) for 5 years had gains in spine and hip BMD and showed larger reductions in bone resorption than bone formation markers. Discontinuation of ODN resulted in reversal of treatment effects

  18. Twenty years of continuous high time resolution volatile organic compound monitoring in the United Kingdom from 1993 to 2012

    NASA Astrophysics Data System (ADS)

    Derwent, R. G.; Dernie, J. I. R.; Dollard, G. J.; Dumitrean, P.; Mitchell, R. F.; Murrells, T. P.; Telling, S. P.; Field, R. A.

    2014-12-01

    Continuous, high frequency observations of C2 - C8 hydrocarbons began in the United Kingdom in 1993 and have continued through to the present day at a range of kerbside, urban background and rural locations. Most of the monitored hydrocarbons have shown dramatic declines in concentrations over the study period, with present levels close to an order of magnitude below their levels in the 1990s. The concentrations of 23 selected hydrocarbons have been aggregated up to give an estimate of the total VOC concentrations. These annual values have shown an exponential decline of -18% yr-1 at the London Marylebone Road kerbside site, -11% yr-1 at the London Eltham urban background site and -22% yr-1 at the rural Harwell site. Similar declines have been reported in UK road transport VOC emissions, demonstrating how the VOC emission inventories have apparently captured the salient features influencing real-world VOC emissions over the 1994-2012 period.

  19. Legionella control in the water system of antiquated hospital buildings by shock and continuous hyperchlorination: 5 years experience

    PubMed Central

    2014-01-01

    Background To control the presence of Legionella in an old hospital water system, an integrated strategy of water disinfection-filtration was implemented in the university hospital Umberto I in Rome. Methods Due to antiquated buildings, hospital water system design and hospital extension (38 buildings), shock hyperchlorination (sodium hypochlorite, 20–50 ppm of free chlorine at distal points for 1–2 h) followed by continuous hyperchlorination (0.5-1.0 mg/L at distal points) were adopted, and microbiological and chemical monitoring of the water supply was carried out in the university hospital (December 2006-December 2011). Results Overall, 1308 samples of cold <20°C (44.5%), mixed ≥20°C ≤ 45°C (37.7%) and hot >45°C (17.8%) water were collected, determining residual free chlorine (0.43 ± 0.44 mg/L), pH (7.43 ± 0.29) and trihalomethanes (8.97 ± 18.56 μg/L). Legionella was isolated in 102 (9.8%) out of 1.041 water samples without filters (L. pneumophila sg 1 17.6%, L. pneumophila sg 2–14 28.4%, L. non pneumophila 53.9%), and in none of the 267 samples with filters. Legionella was recovered in 23 buildings out of 38 and 29 samples (28.4%) exceeded 103 cfu/L. When considering the disinfection treatment Legionella was isolated: before shock hyperchlorination (21.1%), 15 days after shock hyperchlorination (7.8%), 30 days after shock hyperchlorination (3.5%), during continuous hyperchlorination (5.5%) and without continuous hyperchlorination (27.3%). Continuous hyperchlorination following the shock treatment achieved >70% reduction of positive samples, whereas no continuous hyperchlorination after shock treatment was more frequently associated to Legionella isolation (OR 6.41; 95% CI 3.10–13.26; p <0.001). Independent risk factors for Legionella isolation were: residual free chlorine <0.5 mg/L (OR 13.0; 95% CI 1.37 – 123.2; p <0.03), water T° ≥20°C ≤ 45°C (OR 12.0; 95% CI 1.28 – 111.48; p <0.03) and no continuous hyperchlorination after shock

  20. The 2003 National Survey of First-Year Seminars: Continuing Innovations in the Collegiate Curriculum. The First-Year Experience Monograph Series No. 41

    ERIC Educational Resources Information Center

    Tobolowsky, Barbara F.

    2005-01-01

    This volume reports on the sixth triennial National Survey of First-Year Seminar. Data from more than 600 colleges and universities are analyzed to offer information on the structure, content, and administration of these courses. Changes to the survey capture new information on innovative course practices including using undergraduates as…

  1. Showing up Matters: Newark Chronic Absenteeism in the Early Years

    ERIC Educational Resources Information Center

    Chen, Peter; Rice, Cynthia

    2016-01-01

    Based on a 180-day school year, any student who misses 18 days or more per year--or about two days per month--is considered chronically absent. An alarming 4,328 Newark students in grades kindergarten through 3rd grade were chronically absent during the 2013-14 school year. When young students miss too much school, they will likely struggle…

  2. Continuity, Comorbidity and Longitudinal Associations between Depression and Antisocial Behaviour in Middle Adolescence: A 2-Year Prospective Follow-Up Study

    ERIC Educational Resources Information Center

    Ritakallio, Minna; Koivisto, Anna-Maija; von der Pahlen, Bettina; Pelkonen, Mirjami; Marttunen, Mauri; Kaltiala-Heino, Riittakerttu

    2008-01-01

    The study investigated continuity, comorbidity and longitudinal associations between depression Beck depression inventory (RBDI) and antisocial behaviour Youth self-report (YSR) in middle adolescence. Data were used from a community sample of 2070 adolescents who participated in a 2-year prospective follow-up study. The results indicate that both…

  3. ICOM2012: 3rd International Conference on the Physics of Optical Materials and Devices (Belgrade, Serbia, 2-6 September 2012)

    NASA Astrophysics Data System (ADS)

    Dramićanin, Miroslav D.; Antić, Željka; Viana, Bruno

    2013-11-01

    The 3rd International Conference on the Physics of Optical Materials and Devices (ICOM2012) was held in Belgrade (Serbia) from 2 to 6 September 2012 (figure 1). The conference was organized by the Vinča Institute of Nuclear Sciences, University of Belgrade (Serbia) and the Laboratoire de Chimie de la Matière Condensée de Paris (France), and supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia and Optical Society of America. ICOM2012 was a follow-up to the two previous, successful ICOM conferences held in Herceg Novi in 2006 and 2009. The conference aimed at providing a forum for scientists in optical materials to debate on: • Luminescent materials and nanomaterials • Hybrid optical materials (organic/inorganic) • Characterization techniques of optical materials • Luminescence mechanisms and energy transfers • Theory and modeling of optical processes • Ultrafast-laser processing of materials • Optical sensors • Medical imaging • Advanced optical materials in photovoltaics and biophotonics • Photothermal and photoacoustic spectroscopy and phenomena The conference stressed the value of a fundamental scientific understanding of optical materials. A particular accent was put on wide band-gap materials in crystalline, glass and nanocrystalline forms. The applications mainly involved lasers, scintillators and phosphors. Rare earth and transition metal ions introduced as dopants in various hosts were considered, and their impact on the optical properties were detailed in several presentations. This volume contains selected contributions of speakers and participants of the ICOM2012 conference. The conference provided a unique opportunity for about 200 scientists from 32 countries to discuss recent progress in the field of optical materials. During the three and half days, 21 invited talks and 52 contributed lectures were given, with a special event in memory of our dear colleague Professor Dr Tsoltan

  4. A Multiple Regression Analysis of Factors Concerning Superintendent Longevity and Continuity Relative to Student Achievement

    ERIC Educational Resources Information Center

    Plotts, Timothy

    2011-01-01

    The purpose of this quantitative study was to examine the relationship between the length of superintendent tenure, longevity, and continuity relative to student achievement as evidenced by the 2008-2009 3rd Grade New Jersey Assessment of Skills and Knowledge (NJASK) in language arts. Achievement in the study was defined as those students who…

  5. Bolus dose with continuous infusion of midazolam as sedation for outpatient surgery.

    PubMed

    Luyk, N H; Zacharias, M; Wanwimolaruk, S

    1992-06-01

    This double-blind, randomised, cross-over trial in 41 patients for 3rd molar surgery compared the safety, amnesic properties and psychomotor recovery between a bolus injection of midazolam and a bolus injection followed by continuous infusion of midazolam. The latter showed good safety and better amnesia to events during the procedure, but prolonged the recovery time. PMID:1640130

  6. Continuous controlled-infusion of hypertonic saline solution in traumatic brain-injured patients: a 9-year retrospective study

    PubMed Central

    2011-01-01

    Introduction Description of a continuous hypertonic saline solution (HSS) infusion using a dose-adaptation of natremia in traumatic brain injured (TBI) patients with refractory intracranial hypertension (ICH). Methods We performed a single-center retrospective study in a surgical intensive care unit of a tertiary hospital. Fifty consecutive TBI patients with refractory ICH treated with continuous HSS infusion adapted to a target of natremia. In brief, a physician set a target of natremia adapted to the evolution of intracranial pressure (ICP). Flow of NaCl 20% was a priori calculated according to natriuresis, and the current and target natremia that were assessed every 4 hours. Results The HSS infusion was initiated for a duration of 7 (5 to 10) (8 ± 4) days. ICP decreased from 29 (26 to 34) (31 ± 9) mm Hg at H0 to 20 (15 to 26) (21 ± 8) mm Hg at H1 (P < 0.05). Cerebral perfusion pressure increased from 61 (50 to 70) (61 ± 13) mm Hg at H0 up to 67 (60 to 79) (69 ± 12) mm Hg at H1 (P < 0.05). No rebound of ICH was reported after stopping continuous HSS infusion. Natremia increased from 140 (138 to 143) (140 ± 4) at H0 up to 144 (141 to 148) (144 ± 4) mmol/L at H4 (P < 0.05). Plasma osmolarity increased from 275 (268 to 281) (279 ± 17) mmol/L at H0 up to 290 (284 to 307) (297 ± 17) mmol/L at H24 (P < 0.05). The main side effect observed was an increase in chloremia from 111 (107 to 119) (113 ± 8) mmol/L at H0 up to 121 (117 to 124) (121 ± 6) mmol/L at H24 (P < 0.05). Neither acute kidney injury nor pontine myelinolysis was recorded. Conclusions Continuous HSS infusion adapted to close biologic monitoring enables long-lasting control of natremia in TBI patients along with a decreased ICP without any rebound on infusion discontinuation. PMID:22035596

  7. Image Quality of 3rd Generation Spiral Cranial Dual-Source CT in Combination with an Advanced Model Iterative Reconstruction Technique: A Prospective Intra-Individual Comparison Study to Standard Sequential Cranial CT Using Identical Radiation Dose

    PubMed Central

    Wenz, Holger; Maros, Máté E.; Meyer, Mathias; Förster, Alex; Haubenreisser, Holger; Kurth, Stefan; Schoenberg, Stefan O.; Flohr, Thomas; Leidecker, Christianne; Groden, Christoph; Scharf, Johann; Henzler, Thomas

    2015-01-01

    Objectives To prospectively intra-individually compare image quality of a 3rd generation Dual-Source-CT (DSCT) spiral cranial CT (cCT) to a sequential 4-slice Multi-Slice-CT (MSCT) while maintaining identical intra-individual radiation dose levels. Methods 35 patients, who had a non-contrast enhanced sequential cCT examination on a 4-slice MDCT within the past 12 months, underwent a spiral cCT scan on a 3rd generation DSCT. CTDIvol identical to initial 4-slice MDCT was applied. Data was reconstructed using filtered backward projection (FBP) and 3rd-generation iterative reconstruction (IR) algorithm at 5 different IR strength levels. Two neuroradiologists independently evaluated subjective image quality using a 4-point Likert-scale and objective image quality was assessed in white matter and nucleus caudatus with signal-to-noise ratios (SNR) being subsequently calculated. Results Subjective image quality of all spiral cCT datasets was rated significantly higher compared to the 4-slice MDCT sequential acquisitions (p<0.05). Mean SNR was significantly higher in all spiral compared to sequential cCT datasets with mean SNR improvement of 61.65% (p*Bonferroni0.05<0.0024). Subjective image quality improved with increasing IR levels. Conclusion Combination of 3rd-generation DSCT spiral cCT with an advanced model IR technique significantly improves subjective and objective image quality compared to a standard sequential cCT acquisition acquired at identical dose levels. PMID:26288186

  8. Assessment of crop yield losses in Punjab and Haryana using two years of continuous in-situ ozone measurements

    NASA Astrophysics Data System (ADS)

    Sinha, B.; Singh Sangwan, K.; Maurya, Y.; Kumar, V.; Sarkar, C.; Chandra, B. P.; Sinha, V.

    2015-01-01

    In this study we use a high quality dataset of in-situ ozone measurements at a suburban site called Mohali in the state of Punjab to estimate ozone related crop yield losses for wheat, rice, cotton and maize for Punjab and the neighbouring state Haryana for the years 2011-2013. We inter-compare crop yield loss estimates according to different exposure metrics such as AOT40 and M7 for the two major crop growing seasons of Kharif (June-October) and Rabi (November-April) and establish a new crop yield exposure relationship for South Asian wheat and rice cultivars. These are a factor of two more sensitive to ozone induced crop yield losses compared to their European and American counterparts. Relative yield losses based on the AOT40 metrics ranged from 27-41% for wheat, 21-26% for rice, 9-11% for maize and 47-58% for cotton. Crop production losses for wheat amounted to 20.8 million t in fiscal year 2012-2013 and 10.3 million t in fiscal year 2013-2014 for Punjab and Haryana jointly. Crop production losses for rice totalled 5.4 million t in fiscal year 2012-2013 and 3.2 million t year 2013-2014 for Punjab and Haryana jointly. The Indian National Food Security Ordinance entitles ~ 820 million of India's poor to purchase about 60 kg of rice/wheat per person annually at subsidized rates. The scheme requires 27.6 Mt of wheat and 33.6 Mt of rice per year. Mitigation of ozone related crop production losses in Punjab and Haryana alone could provide >50% of the wheat and ~10% of the rice required for the scheme. The total economic cost losses in Punjab and Haryana amounted to USD 6.5 billion in the fiscal year 2012-2013 and USD 3.7 billion in the fiscal year 2013-2014. This economic loss estimate represents a very conservative lower limit based on the minimum support price of the crop, which is lower than the actual production costs. The upper limit for ozone related crop yield losses in entire India currently amounts to 3.5-20% of India's GDP. Mitigation of high surface ozone

  9. Assessment of crop yield losses in Punjab and Haryana using 2 years of continuous in situ ozone measurements

    NASA Astrophysics Data System (ADS)

    Sinha, B.; Singh Sangwan, K.; Maurya, Y.; Kumar, V.; Sarkar, C.; Chandra, B. P.; Sinha, V.

    2015-08-01

    In this study we use a high-quality data set of in situ ozone measurements at a suburban site called Mohali in the state of Punjab to estimate ozone-related crop yield losses for wheat, rice, cotton and maize for Punjab and the neighbouring state Haryana for the years 2011-2013. We intercompare crop yield loss estimates according to different exposure metrics, such as AOT40 (accumulated ozone exposure over a threshold of 40) and M7 (mean 7-hour ozone mixing ratio from 09:00 to 15:59), for the two major crop growing seasons of kharif (June-October) and rabi (November-April) and establish a new crop-yield-exposure relationship for southern Asian wheat, maize and rice cultivars. These are a factor of 2 more sensitive to ozone-induced crop yield losses compared to their European and American counterparts. Relative yield losses based on the AOT40 metrics ranged from 27 to 41 % for wheat, 21 to 26 % for rice, 3 to 5 % for maize and 47 to 58 % for cotton. Crop production losses for wheat amounted to 20.8 ± 10.4 million t in the fiscal year of 2012-2013 and 10.3 ± 4.7 million t in the fiscal year of 2013-2014 for Punjab and Haryana taken together. Crop production losses for rice totalled 5.4 ± 1.2 million t in the fiscal year of 2012-2013 and 3.2 ± 0.8 million t in the year 2013-2014 for Punjab and Haryana taken together. The Indian National Food Security Ordinance entitles ~ 820 million of India's poor to purchase about 60 kg of rice or wheat per person annually at subsidized rates. The scheme requires 27.6 Mt of wheat and 33.6 Mt of rice per year. The mitigation of ozone-related crop production losses in Punjab and Haryana alone could provide > 50 % of the wheat and ~ 10 % of the rice required for the scheme. The total economic cost losses in Punjab and Haryana amounted to USD 6.5 ± 2.2 billion in the fiscal year of 2012-2013 and USD 3.7 ± 1.2 billion in the fiscal year of 2013-2014. This economic loss estimate represents a very conservative lower limit based on

  10. Continuous up to 4 Years Entecavir Treatment of HBV-Infected Adolescents – A Longitudinal Study in Real Life

    PubMed Central

    Pawłowska, Małgorzata; Smok, Beata; Rajewski, Paweł; Wietlicka-Piszcz, Magdalena; Halota, Waldemar; Tretyn, Andrzej

    2016-01-01

    This study evaluated the long-term (up to 4 years) efficacy and safety of entecavir ETV treatment and analysed the significance of baseline and on-treatment factors in long-term ETV outcomes in adolescents with chronic hepatitis B (CHB). We determined the cumulative virological and serological outcomes of 44 adolescents with CHB receiving ETV for up to 4 years. To investigate the dynamics of HBV DNA, ALT activity and hepatitis B e antigen (HBeAg) seroconversion over time and their associations with the considered factors, generalized estimating equation (GEE) models were used. The cumulative rates of undetectable HBV DNA (<20 IU/ml) and HBeAg seroconversion after 4 years were 89.7% and 55.4%, respectively. In the study group, we showed that having undetectable HBV DNA at the 6th or 12th month of therapy predicted the achievement of a sustained response rate (SRR, defined as the loss of HBV DNA, loss of HBeAg and ALT normalization) at year 3 of ETV therapy (P = 0.048, OR = 5.83; P = 0.012; OR = 14.57, respectively). The GEE analysis indicated that of the different factors, the duration of ETV therapy had a strong impact on the achievement of virological suppression, HBeAg seroconversion and SRR in adolescents. Each month after the initiation of therapy, the odds of loss of HBV DNA increased by approximately 5% (OR = 1.05, P<0.0001), on average. Additionally, the GEE analysis revealed that adolescents with an age at infection of ≥10 years had 3 times higher odds of achieving undetectable HBV DNA than patients with a younger infection age (OR = 3.67, P = 0.028). None of the ETV-treated patients reported significant adverse effects. ETV is an effective and safe treatment option for adolescents with CHB. Undetectable HBV DNA in the 6th and/or 12th month of ETV treatment and older age at infection could predict maintained virological suppression. PMID:27685782

  11. Filter Efficiency and Leak Testing of Returned ISS Bacterial Filter Elements After 2.5 Years of Continuous Operation

    NASA Technical Reports Server (NTRS)

    Green, Robert D.; Agui, Juan H.; Berger, Gordon M.; Vijayakumar, R.; Perry, Jay L.

    2016-01-01

    The atmosphere revitalization equipment aboard the International Space Station (ISS) and future deep space exploration vehicles provides the vital functions of maintaining a habitable environment for the crew as well as protecting the hardware from fouling by suspended particulate matter. Providing these functions are challenging in pressurized spacecraft cabins because no outside air ventilation is possible and a larger particulate load is imposed on the filtration system due to lack of sedimentation in reduced gravity conditions. The ISS Environmental Control and Life Support (ECLS) system architecture in the U.S. Segment uses a distributed particulate filtration approach consisting of traditional High-Efficiency Particulate Adsorption (HEPA) filters deployed at multiple locations in each module. These filters are referred to as Bacteria Filter Elements (BFEs). As more experience has been gained with ISS operations, the BFE service life, which was initially one year, has been extended to two to five years, dependent on the location in the U.S. Segment. In previous work we developed a test facility and test protocol for leak testing the ISS BFEs. For this work, we present results of leak testing a sample set of returned BFEs with a service life of 2.5 years, along with particulate removal efficiency and pressure drop measurements. The results can potentially be utilized by the ISS Program to ascertain whether the present replacement interval can be maintained or extended to balance the on-ground filter inventory with extension of the lifetime of ISS to 2024. These results can also provide meaningful guidance for particulate filter designs under consideration for future deep space exploration missions.

  12. BIFROST project: Reprocessing six years of continuous GPS observations and inference of three-dimensional deformation in Fennoscandia

    NASA Astrophysics Data System (ADS)

    Lidberg, M.; Johansson, J. M.; Scherneck, H.; Bergstrand, S.

    2004-05-01

    New solutions are presented from 2000 days of continuous GPS obtained in the permanent networks in Fennoscandia. The period encompasses a prolongated phase of stable observation conditions after January 1998. Several significant improvements have led to narrower uncertainties and lower systematic errors in the new solutions compared to our previous results. Elevation cutoff was lowered to 10 degrees, only sporadically were antenna bias parameters required, and parallel solutions were produced with different softwares and different strategies. We used GAMIT and GIPSY/OASIS-II, the latter in point positioning mode both with and without ambiguity fixing. The new results confirm earlier findings of maximum discrepancies between GIA models and observations in northern Finland. The reason may be related to overestimated ice thickness and glaciation period in the north. In general, the new solutions are more coherent in the velocity field as some of the perturbations could be avoided. We compare GPS rates with sea level rates from tide gauge observations and with model computations.

  13. Joint conference of iMEC 2015 (2nd International Manufacturing Engineering Conference & APCOMS 2015 (3rd Asia-Pacific Conference on Manufacturing Systems)

    NASA Astrophysics Data System (ADS)

    2016-02-01

    The iMEC 2015 is the second International Manufacturing Engineering Conference organized by the Faculty of Manufacturing, Universiti Malaysia Pahang (UMP), held from 12-14th November 2015 in Kuala Lumpur, Malaysia, with a theme "Materials, Manufacturing and Systems for Tomorrow". For the first time, iMEC is organized together with 3rd Asia- Pacific Conference on Manufacturing System (APCOMS 2015) which owned by Fakulti Teknologi Industri, Institut Teknologi Bandung (ITB), Indonesia. This is an extended collaboration between UMP and ITB to intensify knowledge sharing and experiences between higher learning institutions. This conference (iMEC & APCOMS 2015) is a platform for knowledge exchange and the growth of ideas, particularly in manufacturing engineering. The conference aims to bring researchers, academics, scientists, students, engineers and practitioners from around the world together to present their latest findings, ideas, developments and applications related to manufacturing engineering and other related research areas. With rapid advancements in manufacturing engineering, iMEC is an appropriate medium for the associated community to keep pace with the changes. In 2015, the conference theme is “Materials, Manufacturing and Systems for Tomorrow” which reflects the acceleration of knowledge and technology in global manufacturing. The papers in these proceedings are examples of the work presented at the conference. They represent the tip of the iceberg, as the conference attracted over 200 abstracts from Malaysia, Indonesia, Japan, United Kingdom, Australia, India, Bangladesh, South Africa, Turkey and Morocco and 151 full papers were accepted in these proceedings. The conference was run in four parallel sessions with 160 presenters sharing their latest finding in the areas of manufacturing process, systems, advanced materials and automation. The first keynote presentation was given by Prof. B. S. Murthy (IIT, Madras) on "Nanomaterials with Exceptional

  14. Stages of Geoinformation Evolution Related to the Territories Described in the Bible - from the 3Rd Millennium B.C. to Modern Times

    NASA Astrophysics Data System (ADS)

    Linsenbarth, Adam

    2012-09-01

    The paper presents consecutive stages of the evolution of geoinformation related to the territories of the events described in the Bible. Two geoinformation sources are presented: the Bible and non-Bible sources. In the Bible there is much, often some highly detailed information regarding terrain topography. The oldest non-Bible sources are incorporated in the ancient documents, which were discovered in Egypt and Mesopotamia. Some of them are related to the 3rd millen- nium B.C. The further stages are related to the onomasticons and itineraries written by travellers and pilgrims to the Holy Land. The most famous onomasticons include: onomasticons prepared by bishop Eusebius from Caesarea and those pre- pared by St. Jerome. One of the oldest maps of Palestine's territory is the so-called mosaic map of Madaba dated to 565. In the 15th century several Bible maps were edited. The most rapid evolution occurred in the 16th and 17* centuries, when the world famous cartographers such as Mercator and Ortelius edited several maps of Palestine's territory. Cartographers from several European countries edited more than 6,000 maps presenting the Biblical territories and Biblical events. Modem maps, based on detailed topographical surveys, were edited m the second half of the 19* and 20th centuries. W artykule przedstawiono kolejne etapy rozwoju geoinformacji dotyczącej terenówr biblijnych. Omówiono dwa źródła informacji, a mianowicie geoinformacje biblijne i pozabiblijne. W tekstach biblijnych można znaleźć wiele, często bardzo detalicznych informacji topograficznych. Najstarsze źródła pozabiblijne, to starożytne dokumenty odnalezione na terenach Egiptu i Mezopotamii. Niektóre z nich pochodzą z trzeciego milenium przed Chr. Kolejnym etapem geoinformacji były onomastikony oraz dzienniki podróży pisane przez podróżników i pielgrzymów do Ziemi Świętej. Do najbardziej znanych należy onomastikon sporządzony przez biskupa Euzebiusza z Cezarei oraz

  15. [Cold agglutinin disease -  no response to glucocorticoids and rituximab, what treatment is best for the 3rd line of therapy? Case report and review of the literature].

    PubMed

    Adam, Z; Pejchalová, A; Chlupová, G; Ríhová, L; Pour, L; Krejčí, M; Cervinek, L; Král, Z; Mayer, J

    2013-09-01

    in about one  half of treated patients and the remission duration median after rituximab administration is 11 months. A combination of rituximab with fludarabin was more effective, though more toxic; this combination, in a clinical study, led to 75% of patients responding to treatment, including 20% experiencing complete remission. The treatment response median reached over 66 months. In a small study (10 patients) an increase in the amount of rituximab administrations from 4 to 8 led to a treatment response in 6 patients in whom administration of 4 doses of rituximab had no response. When treating Waldenström macroglobulinemia, effectiveness of the following drugs and their combinations was proven: rituximab, chlorambucil, cyclophosphamide, fludarabin, bortezomib, lenalidomid, bendamustin and alemtuzumab. The same drugs and treatment procedures are used for the treatment of the cold agglutinin disease as for Waldenström macroglobulinemia. Successful treatment with vortezomibem, combinations of rituximab + bendamustin, rituximab + cyclophosphamide or rituximab + fludarabin + cyclophosphamide, were recorded in the form of a description as regards the cold agglutinin disease treatment. An important benefit is also shown through treatment with the monoclonal antibody antiC5, eculizumab, which is otherwise used for the treatment of paroxysmal nocturnal haemoglobinuria. Eculizumab blocks the C5 element of the component and thus stops haemolysis in a patient with cold agglutinin disease. As cold agglutinin disease is very rare, there are only a few clinical studies and when treating this rare disease we have no other option than to take into account the information contained in the descriptions of the particular cases of cold agglutinin disease and the experience of Waldenström macroglobulinemia disease treatment. The discussion seeks to solve the issue regarding what 3rd line treatment option to use in the described patient. PMID:24073955

  16. Fifteen years of continuous improvement of quality care of type 2 diabetes mellitus in primary care in Catalonia, Spain

    PubMed Central

    Mata-Cases, M; Roura-Olmeda, P; Berengué-Iglesias, M; Birulés-Pons, M; Mundet-Tuduri, X; Franch-Nadal, J; Benito-Badorrey, B; Cano-Pérez, J F

    2012-01-01

    Aims To assess the evolution of type 2 diabetes mellitus (T2DM) quality indicators in primary care centers (PCC) as part of the Group for the Study of Diabetes in Primary Care (GEDAPS) Continuous Quality Improvement (GCQI) programme in Catalonia. Methods Sequential cross-sectional studies were performed during 1993–2007. Process and outcome indicators in random samples of patients from each centre were collected. The results of each evaluation were returned to each centre to encourage the implementation of correcting interventions. Sixty-four different educational activities were performed during the study period with the participation of 2041 professionals. Results Clinical records of 23,501 patients were evaluated. A significant improvement was observed in the determination of some annual process indicators: HbA1c (51.7% vs. 88.9%); total cholesterol (75.9% vs. 90.9%); albuminuria screening (33.9% vs. 59.4%) and foot examination (48.9% vs. 64.2%). The intermediate outcome indicators also showed significant improvements: glycemic control [HbA1c ≤ 7% (< 57 mmol/mol); (41.5% vs. 64.2%)]; total cholesterol [≤ 200 mg/dl (5.17 mmol/l); (25.5% vs. 65.6%)]; blood pressure [≤ 140/90 mmHg; (45.4% vs. 66.1%)]. In addition, a significant improvement in some final outcome indicators such as prevalence of foot ulcers (7.6% vs. 2.6%); amputations (1.9% vs. 0.6%) and retinopathy (18.8% vs. 8.6%) was observed. Conclusions Although those changes should not be strictly attributed to the GCQI programme, significant improvements in some process indicators, parameters of control and complications were observed in a network of primary care centres in Catalonia. PMID:22340449

  17. The countdown continues. Hospitals and healthcare systems are racing the clock to determine the severity of the year-2000 bug infestation.

    PubMed

    Morrissey, J; Hensley, S

    1998-08-10

    As the clock continues to tick toward the new millennium, healthcare systems are racing to determine the severity of the year-2000 bug infestation. One system putting its computers and medical devices to the test so far has found a 20% failure rate. The system also has found that some devices just can't be tested. As one expert said: "This is not a technology problem; it's a management challenge."

  18. Seawater inundation from the 2011 Tohoku tsunami continues to strongly affect soil bacterial communities 1 year later.

    PubMed

    Asano, Ryoki; Nakai, Yutaka; Kawada, Wataru; Shimura, Yoichiro; Inamoto, Tamio; Fukushima, Jun

    2013-10-01

    The effects of inundation caused by the 2011 Tohoku tsunami on soil bacterial communities in agricultural fields were evaluated. Bacterial communities were compared across three different types of soil, unflooded field (UF) soil, soil flooded for 2 weeks (short term (ST)), and soil flooded for 2 months (long term (LT)), using polymerase chain reaction-pyrosequencing of 16S rRNA genes. Acidobacteria were dominant in UF, with a relative abundance of approximately 35 %, and Proteobacteria dominated flooded soils (30-67 %). Hierarchical cluster analysis indicated that the community structure of soil bacteria in flooded soils (ST and LT) clearly differed from that in UF. Differences between LT and ST fields were rarely observed in terms of chemical properties and microbial community structure at the phylum level. However, sulfur-oxidizing bacteria (SOB) and nitrite-oxidizing bacteria (NOB) in LT tended to occur at high and low abundances, respectively. Halothiobacillus, a halotolerant SOB, was detected in all LT fields. Unexpectedly, a zeta-Proteobacteria, which had previously only been detected in marine environments, was detected in LT fields only. Our results demonstrate that the effects of the 2011 Tohoku tsunami on soil bacterial communities in agricultural fields may have lasted at least 1 year. Furthermore, SOB, NOB, and zeta-Proteobacteria may serve as indicators of the effects of seawater inundation on microorganisms.

  19. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial

    PubMed Central

    Davies, Christina; Pan, Hongchao; Godwin, Jon; Gray, Richard; Arriagada, Rodrigo; Raina, Vinod; Abraham, Mirta; Alencar, Victor Hugo Medeiros; Badran, Atef; Bonfill, Xavier; Bradbury, Joan; Clarke, Michael; Collins, Rory; Davis, Susan R; Delmestri, Antonella; Forbes, John F; Haddad, Peiman; Hou, Ming-Feng; Inbar, Moshe; Khaled, Hussein; Kielanowska, Joanna; Kwan, Wing-Hong; Mathew, Beela S; Müller, Bettina; Nicolucci, Antonio; Peralta, Octavio; Pernas, Fany; Petruzelka, Lubos; Pienkowski, Tadeusz; Rajan, Balakrishnan; Rubach, Maryna T; Tort, Sera; Urrútia, Gerard; Valentini, Miriam; Wang, Yaochen; Peto, Richard

    2013-01-01

    Summary Background For women with oestrogen receptor (ER)-positive early breast cancer, treatment with tamoxifen for 5 years substantially reduces the breast cancer mortality rate throughout the first 15 years after diagnosis. We aimed to assess the further effects of continuing tamoxifen to 10 years instead of stopping at 5 years. Methods In the worldwide Adjuvant Tamoxifen: Longer Against Shorter (ATLAS) trial, 12 894 women with early breast cancer who had completed 5 years of treatment with tamoxifen were randomly allocated to continue tamoxifen to 10 years or stop at 5 years (open control). Allocation (1:1) was by central computer, using minimisation. After entry (between 1996 and 2005), yearly follow-up forms recorded any recurrence, second cancer, hospital admission, or death. We report effects on breast cancer outcomes among the 6846 women with ER-positive disease, and side-effects among all women (with positive, negative, or unknown ER status). Long-term follow-up still continues. This study is registered, number ISRCTN19652633. Findings Among women with ER-positive disease, allocation to continue tamoxifen reduced the risk of breast cancer recurrence (617 recurrences in 3428 women allocated to continue vs 711 in 3418 controls, p=0·002), reduced breast cancer mortality (331 deaths vs 397 deaths, p=0·01), and reduced overall mortality (639 deaths vs 722 deaths, p=0·01). The reductions in adverse breast cancer outcomes appeared to be less extreme before than after year 10 (recurrence rate ratio [RR] 0·90 [95% CI 0·79–1·02] during years 5–9 and 0·75 [0·62–0·90] in later years; breast cancer mortality RR 0·97 [0·79–1·18] during years 5–9 and 0·71 [0·58–0·88] in later years). The cumulative risk of recurrence during years 5–14 was 21·4% for women allocated to continue versus 25·1% for controls; breast cancer mortality during years 5–14 was 12·2% for women allocated to continue versus 15·0% for controls (absolute mortality

  20. A one year long continuous record of seismic activity and surface motion at the tongue of Rhonegletscher (Valais, Switzerland)

    NASA Astrophysics Data System (ADS)

    Dalban Canassy, Pierre; Röösli, Claudia; Walter, Fabian; Gabbi, Jeannette

    2014-05-01

    A critical gap in our current understanding of glaciers is how high sub-glacial water pressure controls the coupling of the glacier to its bed. Processes at the base of a glacier are inherently difficult to investigate due to their remoteness. Investigation of the sub-glacial environment with passive seismic methods is an innovative, rapidly growing interdisciplinary and promising endeavor. In combination with observations of surface motion and basal water pressure, this method is ideally suited to localize and quantify frictional and fracture processes which occur during periods of rapidly changing sub-glacial water pressure with consequent stress redistribution at the contact interface between ice and bed. Here we present the results of the first one-year-long glacier seismic monitoring performed on an Alpine glacier to our knowledge. Together with records of surface motion and hydrological measurements, we examine whether seasonal changes can be captured by seismic recording. Experiments were carried out from June 2012 to July 2013 on Rhonegletscher (Valais, Switzerland), by means of 3 three-components seismometers settled close to the tongue in 2 meters boreholes. An additional array of eleven sensors installed at the ice surface was also maintained during September 2012, in order to achieve more accurate icequakes locations. A high seismic emission is observed on Rhonegletscher, with icequakes located close to the surface or in the vicinity of the bedrock. The temporal distribution of seismic activity is shown to nicely reflect the seasonal evolution of the glacier hydrology, with a dramatic seismic release in early spring. During summer, released seismic activity is generally driven by diurnal ice/snow melting cycle. In winter, snow-cover conditions are associated with a reduced seismic release, with nevertheless some unexpected activity possibly related to snow-pack metamorphism. Based on icequake locations derived from data recorded in September, we discuss

  1. Continuous long-term immunomodulatory therapy in relapsing multiple sclerosis: results from the 15-year analysis of the US prospective open-label study of glatiramer acetate.

    PubMed

    Ford, C; Goodman, A D; Johnson, K; Kachuck, N; Lindsey, J W; Lisak, R; Luzzio, C; Myers, L; Panitch, H; Preiningerova, J; Pruitt, A; Rose, J; Rus, H; Wolinsky, J

    2010-03-01

    The ongoing US Glatiramer Acetate (GA) Trial is the longest evaluation of continuous immunomodulatory therapy in relapsing-remitting multiple sclerosis (RRMS). The objective of this study was to evaluate up to 15 years of GA as a sole disease-modifying therapy. Two hundred and thirty-two patients received at least one GA dose since study initiation in 1991 (mITT cohort), and 100 (43%, Ongoing cohort) continued as of February 2008. Patients were evaluated every 6 months using the Expanded Disability Status Scale (EDSS). Mean GA exposures were 8.6 +/- 5.2, 4.81 +/- 3.69, and 13.6 +/- 1.3 years and mean disease durations were 17, 13, and 22 years for mITT, Withdrawn and Ongoing cohorts, respectively. For Ongoing patients, annual relapse rates (ARRs) maintained a decline from 1.12 +/- 0.82 at baseline to 0.25 +/- 0.34 per year; 57% had stable/improved EDSS scores (change < or = 0.5 points); 65% had not transitioned to secondary progressive multiple sclerosis (SPMS); 38%, 18%, and 3% reached EDSS 4, 6, and 8. For all patients on GA therapy (the mITT cohort), ARRs declined from 1.18 +/- 0.82 to 0.43 +/- 0.58 per year; 54% had stable/improved EDSS scores; 75% had not transitioned to SPMS; 39%, 23%, and 5% reached EDSS 4, 6, and 8. In conclusion, multiple sclerosis patients with mean disease duration of 22 years administering GA for up to 15 years had reduced relapse rates, and decreased disability progression and transition to SPMS. There were no long-term safety issues.

  2. Year-long continuous personal exposure to PM 2.5 recorded by a fast responding portable nephelometer

    NASA Astrophysics Data System (ADS)

    Braniš, Martin; Kolomazníková, Jana

    2010-08-01

    Personal exposure to particulate matter of aerodynamic diameter under 2.5 μm (PM 2.5) was monitored using a DustTrak nephelometer. The battery-operated unit, worn by an adult individual for a period of approximately one year, logged integrated average PM 2.5 concentrations over 5 min intervals. A detailed time-activity diary was used to record the experimental subject's movement and the microenvironments visited. Altogether 239 days covering all the months (except April) were available for the analysis. In total, 60 463 acceptable 5-min averages were obtained. The dataset was divided into 7 indoor and 4 outdoor microenvironments. Of the total time, 84% was spent indoors, 10.9% outdoors and 5.1% in transport. The indoor 5-min PM 2.5 average was higher (55.7 μg m -3) than the outdoor value (49.8 μg m -3). The highest 5-min PM 2.5 average concentration was detected in restaurant microenvironments (1103 μg m -3), the second highest 5-min average concentration was recorded in indoor spaces heated by stoves burning solid fuels (420 μg m -3). The lowest 5-min mean aerosol concentrations were detected outdoors in rural/natural environments (25 μg m -3) and indoors at the monitored person's home (36 μg m -3). Outdoor and indoor concentrations of PM 2.5 measured by the nephelometer at home and during movement in the vicinity of the experimental subject's home were compared with those of the nearest fixed-site monitor of the national air quality monitoring network. The high correlation coefficient (0.78) between the personal and fixed-site monitor aerosol concentrations suggested that fixed-site monitor data can be used as proxies for personal exposure in residential and some other microenvironments. Collocated measurements with a reference method (β-attenuation) showed a non-linear systematic bias of the light-scattering method, limiting the use of direct concentration readings for exact exposure analysis.

  3. Water Resources Data, Georgia, 2002--Volume 1: Continuous water-level, streamflow, water-quality data, and periodic water-quality data, Water Year 2002

    USGS Publications Warehouse

    Hickey, Andrew C.; Kerestes, John F.; McCallum, Brian E.

    2002-01-01

    Water resources data for the 2002 water year for Georgia consists of records of stage, discharge, and water quality of streams; and the stage and contents of lakes and reservoirs published in two volumes in a digital format on a CD-ROM. Volume one of this report contains water resources data for Georgia collected during water year 2002, including: discharge records of 154 gaging stations; stage for 165 gaging stations; precipitation for 105 gaging stations; information for 20 lakes and reservoirs; continuous water-quality records for 27 stations; the annual peak stage and annual peak discharge for 72 crest-stage partial-record stations; and miscellaneous streamflow measurements at 50 stations, and miscellaneous water-quality data recorded by the NAWQA program in Georgia. Volume two of this report contains water resources data for Georgia collected during calendar year 2002, including continuous water-level records of 155 ground-water wells and periodic records at 132 water-quality stations. These data represent that part of the National Water Data System collected by the U.S. Geological Survey and cooperating State and Federal agencies in Georgia.

  4. Water Resources Data, Georgia, 2003, Volume 1: Continuous water-level, streamflow, water-quality data, and periodic water-quality data, Water Year 2003

    USGS Publications Warehouse

    Hickey, Andrew C.; Kerestes, John F.; McCallum, Brian E.

    2004-01-01

    Water resources data for the 2003 water year for Georgia consists of records of stage, discharge, and water quality of streams; and the stage and contents of lakes and reservoirs published in two volumes in a digital format on a CD-ROM. Volume one of this report contains water resources data for Georgia collected during water year 2003, including: discharge records of 163 gaging stations; stage for 187 gaging stations; precipitation for 140 gaging stations; information for 19 lakes and reservoirs; continuous water-quality records for 40 stations; the annual peak stage and annual peak discharge for 65 crest-stage partial-record stations; and miscellaneous streamflow measurements at 36 stations, and miscellaneous water-quality data at 162 stations in Georgia. Volume two of this report contains water resources data for Georgia collected during calendar year 2003, including continuous water-level records of 156 ground-water wells and periodic records at 130 water-quality stations. These data represent that part of the National Water Data System collected by the U.S. Geological Survey and cooperating State and Federal agencies in Georgia.

  5. Soil evolution and climate dynamics in dry steppes of the Privolzhskaya Upland during the last 3500 years

    NASA Astrophysics Data System (ADS)

    Demkin, V. A.; Demkina, T. S.; Khomutova, T. E.; El'tsov, M. V.

    2012-12-01

    The investigation of paleosols of different ages buried under archaeological monuments of the Bronze (16th-15th centuries BC), Early Iron (2nd-3rd centuries AD), and Medieval (14th century AD) ages demonstrated that the evolution of chestnut soils and solonetzes in the dry steppes of the southern part of the Privolzhskaya Upland during the past 3500 years manifested itself at the level of the genus and species characteristics of the soils, such as the degree of the solonetzicity, the humus content, and the content and composition of the soluble salts. The revealed regularities of the variations of the morphological, chemical, and microbiological soil properties in time allowed reconstructing the secular dynamics of the climatic humidity in the region. It was found that the humidization of the climate with a decrease in the degree of the climatic continentality took place in the middle of the second millennium BC. The Late Sarmatian Time (2nd-3rd centuries AD) was characterized by arid climatic conditions, whereas the Golden Horde time (13th-14th centuries AD) was marked by the general humidization of the climate. A gradual aridization of the climate began in the second half of the 14th century and continued in the 15th century AD.

  6. Water Resources Data, Georgia, 2001, Volume 1: Continuous water-level, streamflow, water-quality data, and periodic water-quality data, Water Year 2001

    USGS Publications Warehouse

    McCallum, Brian E.; Kerestes, John F.; Hickey, Andrew C.

    2001-01-01

    Water resources data for the 2001 water year for Georgia consists of records of stage, discharge, and water quality of streams; and the stage and contents of lakes and reservoirs published in two volumes in a digital format on a CD-ROM. Volume one of this report contains water resources data for Georgia collected during water year 2001, including: discharge records of 133 gaging stations; stage for 144 gaging stations; precipitation for 58 gaging stations; information for 19 lakes and reservoirs; continuous water-quality records for 17 stations; the annual peak stage and annual peak discharge for 76 crest-stage partial-record stations; and miscellaneous streamflow measurements at 27 stations, and miscellaneous water-quality data recorded by the NAWQA program in Georgia. Volume two of this report contains water resources data for Georgia collected during calendar year 2001, including continuous water-level records of 159 ground-water wells and periodic records at 138 water-quality stations. These data represent that part of the National Water Data System collected by the U.S. Geological Survey and cooperating State and Federal agencies in Georgia. Note: Historically, this report was published as a paper report. For the 1999 and subsequent water-year reports, the Water Resources Data for Georgia changed to a new, more informative and functional format on CD-ROM. The format is based on a geographic information system (GIS) user interface that allows the user to view map locations of the hydrologic monitoring stations and networks within respective river basins.

  7. Resolution of epoetin-induced pure red cell aplasia 2 years later, successful re-challenge with continuous erythropoiesis receptor stimulator.

    PubMed

    Lim, Soo Kun; Bee, Ping Chong; Keng, Tee Chau; Chong, Yip Boon

    2013-09-01

    Epoetin-induced pure red cell aplasia (PRCA) is most commonly associated with epoetin-a; nevertheless, its occurrence has been reported in epoetin-β and darbepoetin-a. We report a young hemodialysis patient who developed PRCA 2 years after receiving intravenous epoetin-β. Epoetin- induced PRCA was confirmed by bone marrow aspiration, associated with markedly elevated anti-erythropoietin antibody. He was treated with prednisolone and cyclophosphamide for 3 months but continued to be transfusion-dependent. 17 months after the development of PRCA, he was started on intravenous continuous erythropoiesis receptor stimulator (CERA) in view of frequent transfusions. He tolerated the CERA injection well and the hemoglobin level stabilized 7 months later. Repeat bone marrow aspiration confirmed complete resolution of PRCA with disappearance of anti-erythropoietin antibody. To date, he maintained a stable hemoglobin level and has been transfusion-independent for the past 1 year. This is the first in the literature that reported the utilization of CERA in epoetin-induced PRCA. Very low or undetectable level of anti-erythropoietin antibody might be the key to the success of re-challenge strategy in cases of epoetininduced PRCA. Thus, routine checking of anti-erythropoietin antibody before the rechallenge with an alternative erythropoietin product is highly recommended. PMID:23298519

  8. Higher-order statistical moments and a procedure that detects potentially anomalous years as two alternative methods describing alterations in continuous environmental data

    USGS Publications Warehouse

    Arismendi, Ivan; Johnson, Sherri L.; Dunham, Jason

    2015-01-01

    Statistics of central tendency and dispersion may not capture relevant or desired characteristics of the distribution of continuous phenomena and, thus, they may not adequately describe temporal patterns of change. Here, we present two methodological approaches that can help to identify temporal changes in environmental regimes. First, we use higher-order statistical moments (skewness and kurtosis) to examine potential changes of empirical distributions at decadal extents. Second, we adapt a statistical procedure combining a non-metric multidimensional scaling technique and higher density region plots to detect potentially anomalous years. We illustrate the use of these approaches by examining long-term stream temperature data from minimally and highly human-influenced streams. In particular, we contrast predictions about thermal regime responses to changing climates and human-related water uses. Using these methods, we effectively diagnose years with unusual thermal variability and patterns in variability through time, as well as spatial variability linked to regional and local factors that influence stream temperature. Our findings highlight the complexity of responses of thermal regimes of streams and reveal their differential vulnerability to climate warming and human-related water uses. The two approaches presented here can be applied with a variety of other continuous phenomena to address historical changes, extreme events, and their associated ecological responses.

  9. International Meeting To Discuss Audio Technology as Applied to Library Services for Blind Individuals (3rd, Toronto, Ontario, Canada, April 20-22, 1995). Volumes 1-3.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. National Library Service for the Blind and Physically Handicapped.

    This three-day conference on the subject of audio technology for the production of materials for the blind, takes the court reporter approach to recording the speeches and discussions of the meeting. The result is a three volume set of complete transcripts, one volume for each day of the meeting, but continuous in form. The highlights of each…

  10. Four Thrombotic Events Over 5 Years, Two Pulmonary Emboli and Two Deep Venous Thrombosis, When Testosterone-HCG Therapy Was Continued Despite Concurrent Anticoagulation in a 55-Year-Old Man With Lupus Anticoagulant

    PubMed Central

    Glueck, Charles J.; Lee, Kevin; Prince, Marloe; Jetty, Vybhav; Shah, Parth; Wang, Ping

    2016-01-01

    Background: When exogenous testosterone or treatments to elevate testosterone (human chorionic gonadotropin [HCG] or Clomid) are prescribed for men who have antecedent thrombophilia, deep venous thrombosis and pulmonary embolism often occur and may recur despite adequate anticoagulation if testosterone therapy is continued. Case Presentation: A 55-year-old white male was referred to us because of 4 thrombotic events, 3 despite adequate anticoagulation over a 5-year period. We assessed interactions between thrombophilia, exogenous testosterone therapy, and recurrent thrombosis. In 2009, despite low-normal serum testosterone 334 ng/dL (lower normal limit [LNL] 300 ng/dL), he was given testosterone (TT) cypionate (50 mg/week) and human chorionic gonadotropin (HCG; 500 units/week) for presumed hypogonadism. Ten months later, with supranormal serum T (1385 ng/dL, upper normal limit [UNL] 827 ng/dL) and estradiol (E2) 45 pg/mL (UNL 41 pg/mL), he had a pulmonary embolus (PE) and was then anticoagulated for 2 years (enoxaparin, then warfarin). Four years later, on TT-HCG, he had his first deep venous thrombosis (DVT). TT was stopped and HCG continued; he was anticoagulated (enoxaparin, then warfarin, then apixaban, then fondaparinux). One year after his first DVT, on HCG, still on fondaparinux, he had a second DVT (5/315), was anticoagulated (enoxaparin + warfarin), with a Greenfield filter placed, but 8 days later had a second PE. Thrombophilia testing revealed the lupus anticoagulant. After stopping HCG, and maintained on warfarin, he has been free of further DVT-PE for 9 months. Conclusion: When DVT-PE occur on TT or HCG, in the presence of thrombophilia, TT-HCG should be stopped, lest DVT-PE reoccur despite concurrent anticoagulation. PMID:27536705

  11. Presentations from the 3rd Workshop On Super Flavor Factory Based On Linear Collider Technology (Super B III) ,14-16 Jun 2006, Menlo Park, California

    SciTech Connect

    MacFarlane, D.

    2006-11-10

    This workshop was aimed at continuing discussions of the design for a very high luminosity e{sup +}e{sup -} collider using many of the same technical approaches as for the International Linear Collider. On this basis, the previous two meetings at Frascati have explored several new and promising ideas for reaching luminosities as high as 10{sup 36} cm{sup -2} s{sup -1} or more. We expect to continue the development of a coherent concept for the machine at the June meeting, ultimately aiming at a full written description of the concept by the end of 2006. The workshop also studied the capability of SuperB for a full range of flavor physics, and the corresponding requirements and demands on the associated detector.

  12. Shared Successes, Continuing Challenges: Fostering IDEA and Title I Collaboration. Proceedings of the Council of Chief State School Officers and the Policymaker Partnership Peer Consultation (3rd, Baltimore, Maryland, December 11-14, 2001).

    ERIC Educational Resources Information Center

    Gaston, Caroline

    The Council of Chief State School Officers (CCSSO) and the Policymaker Partnership (PMP) of the National Association of State Directors of Special Education have joined together to consider challenges and opportunities for coordinating special and compensatory education among states, districts, and schools. As part of this effort toward increasing…

  13. Continuous Gravity Monitoring in South America with Superconducting and Absolute Gravimeters: More than 12 years time series at station TIGO/Concepcion (Chile)

    NASA Astrophysics Data System (ADS)

    Wziontek, Hartmut; Falk, Reinhard; Hase, Hayo; Armin, Böer; Andreas, Güntner; Rongjiang, Wang

    2016-04-01

    As part of the Transportable Integrated Geodetic Observatory (TIGO) of BKG, the superconducting gravimeter SG 038 was set up in December 2002 at station Concepcion / Chile to record temporal gravity variations with highest precision. Since May 2006 the time series was supported by weekly observations with the absolute gravimeter FG5-227, proving the large seasonal variations of up to 30 μGal and establishing a gravity reference station in South America. With the move of the whole observatory to the new location near to La Plata / Argentina the series was terminated. Results of almost continuously monitoring gravity variations for more than 12 years are presented. Seasonal variations are interpreted with respect of global and local water storage changes and the impact of the 8.8 Maule Earthquake in February 2010 is discussed.

  14. [Continuous nebulization with terbutaline sulfate under tent inhalation. Evaluation of the efficacy in children 2 to 5 years of age in asthmatic crises].

    PubMed

    Lotufo, J P; Ejzenberg, B; Vieira, S; Mukai, L; Macedo, H; Yamashita, C; Ventura, G; Baldacci, E R; Okay, Y

    1998-06-01

    This study investigated the efficacy of a system for continuous nebulization of terbutaline sulphate in the treatment of acute asthmatic crises in children. The equipment consisted of a condensation nebulizer attached to a 40 liter acrylic tent placed around the patient's head. A prospective, randomized and open clinical trial was conducted. Twenty eight children, 2 to 5 year-old, in acute asthmatic crises were selected. Fourteen were nebulized with terbutaline sulphate while in the control group the aerosolization was proceeded only with half diluted physiologic serum. All patients were administered aminophyline intravenously. The parameter used to evaluate the efficacy of the terbutaline sulphate nebulizing system was clinical improvement measured by the Wood-Downes Score. Two additional parameters indicating terbutaline sulphate absorption were used: reduction of potassium seric levels and positive chronotropic effect. The group treated with terbutaline sulphate showed greater clinical improvement than control group at the 12 hour protocol evaluation as well as lower seric potassium level. A positive chronotropic effect was also observed at the final protocol evaluation. The data showed, preliminarily, that (a) the system for continuous nebulization of terbutaline sulphate was effective in treatment of children's acute asthmatic crises, and (b) there was evidence attesting to the absorption of terbutaline sulphate by the children treatment with it. PMID:9677633

  15. Ten years of soil CO2 continuous monitoring on Mt. Etna: Exploring the relationship between processes of soil degassing and volcanic activity

    NASA Astrophysics Data System (ADS)

    Liuzzo, Marco; Gurrieri, Sergio; Giudice, Gaetano; Giuffrida, Giovanni

    2013-08-01

    The measurement of soil CO2 flux variations is a well-established practice in many volcanic areas around the world. Until recently, however, most of these were made using direct sampling methods. These days, a variety of automatic devices providing real-time data now make the continuous monitoring of volcanic areas possible. A network of automatic geochemical monitoring stations (EtnaGas network) was developed by INGV Palermo and installed at various sites on the flanks of Mt. Etna. Here, we present a large set of soil CO2 flux data recorded by the network, dating back 10 years, a period in which several noteworthy eruptive phenomena occurred. Our statistical analysis strongly suggests that anomalous measurements of soil CO2 flux are attributable to volcanic origin and in almost all cases precede volcanic activity. Here, we present the actual data series recorded by EtnaGAS and an interpretative model of the expected behavior of soil CO2 flux (in terms of increase-decrease cycles), which corresponded well with the volcanic activity during this period. Through the use of a comparative approach, incorporating both volcanological and geochemical data, the global soil CO2 flux trends are put into a coherent framework, highlighting close links between the time flux variations and volcanic activities. These insights, made possible from 10 years of uninterrupted data, confirm the importance of continuous monitoring of volcanic soil degassing, and may contribute in the forecasting of imminent eruptive activity or the temporal evolution of an in-progress eruption, therefore facilitating Civil Defense planning in volcanic areas under high-hazard conditions.

  16. Crossing the Intercultural Borders into 3rd Space Culture(s): Implications for Teacher Education in the Twenty-First Century

    ERIC Educational Resources Information Center

    Dooly, Melinda Ann

    2011-01-01

    This article looks at a year-long network-based exchange between two groups of student-teachers in Spain and the USA, who were involved in various network-based collaborative activities as part of their teaching education. Their online interaction was facilitated through diverse communicative modes such as Skype, Moodle, Voicethread and Second…

  17. La Mancha Plus Two--1970: Proceedings of the Annual Model Secondary School Conference (3rd, University of Vermont, April 24-25, 1970).

    ERIC Educational Resources Information Center

    Manchel, Frank, Ed.; Clark, Virginia, Ed.

    Ten papers assess 3 years of the La Mancha Project whose basic objectives are to devise methods and materials to help students write more effectively, to coordinate the students' writing experiences in English with their other academic classes and life outside school, to provide an in-service training program for secondary school teachers on the…

  18. Focusing the Debate for Positive Change in Teacher Education. Proceedings of the Forum on Teacher Education (3rd, Little Rock, Arkansas, March 1987).

    ERIC Educational Resources Information Center

    Education Commission of the States, Denver, CO.

    In the third regional forum on positive change in teacher education, two themes dominated discussions: the pros and cons of the "fifth-year" plan for teacher education, and the impact and future of standardized testing. In both areas, a major emphasis on traditonally black institutions emerged. This report outlines the discussions, and presents…

  19. Cheyne-Stokes respiration in congestive heart failure: continuous positive airway pressure of 5-8 cm H2O for 1 year in five cases.

    PubMed

    Yasuma, Fumihiko

    2005-01-01

    Five adult patients with congestive heart failure (CHF) due to dilated cardiomyopathy complicated by Cheyne-Stokes respiration/central sleep apnea (CSR/CSA) were treated with continuous positive airway pressure (CPAP) with an initial pressure of 5 cm H2O. Four patients were followed up for 12 months with CPAP of 5 cm H2O. The rest, a 93-year-old patient, was followed up for 30 months, and the CPAP was reset at 8 cm H2O due to worsened cardiac function after 6 months and it was reset at 6 cm H2O due to dryness of the nose after 23 months. For all the patients with nightly CPAP use for 6.0+/-1.4 h per day for a year, frequency of CSR/CSA was significantly reduced after 3 and 12 months with CPAP (p<0.05). Moreover, their symptoms, cardiac function and sleep quality were significantly improved after 3 months (p<0.05), and were maintained above the pre-CPAP levels after 12 months, except for the oldest patient whose cardiac function tended to deteriorate. The results suggest that CSR/CSA in CHF can be treated with CPAP set at a lower pressure than the conventional method, and that CPAP at 5-8 cm H2O is often effective in eliminating CSR/CSA, improving sleep quality, and presumably maintaining cardiac function.

  20. Water Resources Data, Georgia, 2000, Volume 1: Continuous water-level, streamflow, water-quality data, and periodic water-quality data, Water Year 2000

    USGS Publications Warehouse

    McCallum, Brian E.; Hickey, Andrew C.

    2000-01-01

    Water resources data for the 2000 water year for Georgia consists of records of stage, discharge, and water quality of streams; and the stage and contents of lakes and reservoirs published in one volume in a digital format on a CD-ROM. This volume contains discharge records of 125 gaging stations; stage for 20 gaging stations; information for 18 lakes and reservoirs; continuous water-quality records for 10 stations; the annual peak stage and annual peak discharge for 77 crest-stage partial-record stations; and miscellaneous streamflow measurements at 21 stations. These data represent that part of the National Water Data System collected by the U.S. Geological Survey and cooperating State and Federal agencies in Georgia. Note: Historically, this report was published as a paper report. For the 1999 and subsequent water-year reports, the Water Resources Data for Georgia changed to a new, more informative and functional format on CD-ROM. The format is based on a geographic information system (GIS) user interface that allows the user to view map locations of the hydrologic monitoring stations and networks within respective river basins.

  1. Do Automated Peritoneal Dialysis and Continuous Ambulatory Peritoneal Dialysis Have the Same Clinical Outcomes? A Ten-year Cohort Study in Taiwan

    PubMed Central

    Tang, Chao-Hsiun; Chen, Tso-Hsiao; Fang, Te-Chao; Huang, Siao-Yuan; Huang, Kuan-Chih; Wu, Yu-Ting; Wang, Chia-Chen; Sue, Yuh-Mou

    2016-01-01

    This paper reports a comprehensive comparison for mortality and technique failure rates between automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) in Taiwan. A propensity-score matched cohort study was conducted by retrieving APD and CAPD patients identified from the Taiwan National Health Insurance Research Database between 2001 and 2010. The main outcomes were the 5-year mortality and technique failure rates. Further analyses were then carried out based upon the first (2001–2004), second (2005–2007), and third (2008–2010) sub-periods. Similar baseline characteristics were identified for APD (n = 2,287) and CAPD (n = 2,287) patients. The proportion on APD therapy increased rapidly in the second sub-period. As compared to CAPD patients of this sub-period, APD patients had a significantly higher risk of mortality (HR, 1.37; 95% CI 1.09–1.72; p < 0.01) and technique failure (HR, 1.43; 95% CI, 1.10–1.86; p < 0.01), particularly in the first year after peritoneal dialysis commencement. However, APD patients had similar mortality and technique failure rates to those of CAPD patients throughout the full sample period and the first and third sub-periods. These findings do not suggest the presence of a clear advantage of CAPD over APD. Differences observed between these two modalities might be attributed to specials circumstances of sub-periods. PMID:27388055

  2. Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options—a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference

    PubMed Central

    Kirchhof, Paulus; Lip, Gregory Y.H.; Van Gelder, Isabelle C.; Bax, Jeroen; Hylek, Elaine; Kaab, Stefan; Schotten, Ulrich; Wegscheider, Karl; Boriani, Giuseppe; Brandes, Axel; Ezekowitz, Michael; Diener, Hans; Haegeli, Laurent; Heidbuchel, Hein; Lane, Deirdre; Mont, Luis; Willems, Stephan; Dorian, Paul; Aunes-Jansson, Maria; Blomstrom-Lundqvist, Carina; Borentain, Maria; Breitenstein, Stefanie; Brueckmann, Martina; Cater, Nilo; Clemens, Andreas; Dobrev, Dobromir; Dubner, Sergio; Edvardsson, Nils G.; Friberg, Leif; Goette, Andreas; Gulizia, Michele; Hatala, Robert; Horwood, Jenny; Szumowski, Lukas; Kappenberger, Lukas; Kautzner, Josef; Leute, Angelika; Lobban, Trudie; Meyer, Ralf; Millerhagen, Jay; Morgan, John; Muenzel, Felix; Nabauer, Michael; Baertels, Christoph; Oeff, Michael; Paar, Dieter; Polifka, Juergen; Ravens, Ursula; Rosin, Ludger; Stegink, W.; Steinbeck, Gerhard; Vardas, Panos; Vincent, Alphons; Walter, Maureen; Breithardt, Günter; Camm, A. John

    2012-01-01

    While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF. PMID:21791573

  3. Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference.

    PubMed

    Kirchhof, Paulus; Lip, Gregory Y H; Van Gelder, Isabelle C; Bax, Jeroen; Hylek, Elaine; Kaab, Stefan; Schotten, Ulrich; Wegscheider, Karl; Boriani, Giuseppe; Brandes, Axel; Ezekowitz, Michael; Diener, Hans; Haegeli, Laurent; Heidbuchel, Hein; Lane, Deirdre; Mont, Luis; Willems, Stephan; Dorian, Paul; Aunes-Jansson, Maria; Blomstrom-Lundqvist, Carina; Borentain, Maria; Breitenstein, Stefanie; Brueckmann, Martina; Cater, Nilo; Clemens, Andreas; Dobrev, Dobromir; Dubner, Sergio; Edvardsson, Nils G; Friberg, Leif; Goette, Andreas; Gulizia, Michele; Hatala, Robert; Horwood, Jenny; Szumowski, Lukas; Kappenberger, Lukas; Kautzner, Josef; Leute, Angelika; Lobban, Trudie; Meyer, Ralf; Millerhagen, Jay; Morgan, John; Muenzel, Felix; Nabauer, Michael; Baertels, Christoph; Oeff, Michael; Paar, Dieter; Polifka, Juergen; Ravens, Ursula; Rosin, Ludger; Stegink, W; Steinbeck, Gerhard; Vardas, Panos; Vincent, Alphons; Walter, Maureen; Breithardt, Günter; Camm, A John

    2012-01-01

    While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF. PMID:21791573

  4. Post waterflood CO{sub 2} miscible flood in light oil, fluvial-dominated deltaic reservoirs. 3rd Quarterly report, April 1, 1994--June 30, 1994

    SciTech Connect

    Not Available

    1994-07-15

    Production from the Port Neches CO{sub 2} continue to improve. five wells responded to CO{sub 2} injection and currently are flowing with the exception of well No. 6, which has been placed on gas lift to draw the CO{sub 2} to the vicinity. Current production is about 400 BOPD from the five producing wells. Total CO{sub 2} injection is averaging 10 MMCFD, including 4 MMCFD purchased from Cardox and 6 MMCFD of recycled gas. Reservoir pressure increased from 2697 psi in May, to 2890 psi in June due to over-injection. An additional water injection pump was installed to handle the increasing volume of produced water. Also a workover was performed on Well No. 33 to take out the gas lift valves and eliminate communication. Two papers were presented at the SPE/DOE symposium that was held in Tulsa this April. The screening model has been released to the DOE and was made public during the month of May.

  5. Highlights from the 11-year record of tropospheric ozone from OMI/MLS and continuation of that long record using OMPS measurements

    NASA Astrophysics Data System (ADS)

    Ziemke, Jerry; Kramarova, Natalya; Bhartia, Pawan; Degenstein, Doug; Deland, Matthew

    2016-04-01

    Since October 2004 the Ozone Monitoring Instrument (OMI) and Microwave Limb Sounder (MLS) onboard the Aura satellite have provided over 11 years of continuous tropospheric ozone measurements. These OMI/MLS measurements have been used in many studies to evaluate dynamical and photochemical effects caused by ENSO, the Madden-Julian Oscillation (MJO) and shorter timescales, as well as long-term trends and the effects of deep convection on tropospheric ozone. Given that the OMI and MLS instruments have now extended well beyond their expected lifetimes, our goal is to continue their long record of tropospheric ozone using recent Ozone Mapping Profiler Suite (OMPS) measurements. The OMPS onboard the Suomi National Polar-orbiting Partnership NPP satellite was launched on October 28, 2011 and is comprised of three instruments: the nadir mapper, the nadir profiler, and the limb profiler. Our study combines total column ozone from the OMPS nadir mapper with stratospheric column ozone from the OMPS limb profiler to measure tropospheric ozone residual. The time period for the OMPS measurements is March 2012 - present. For the OMPS limb profiler retrievals, the OMPS v2 algorithm from Goddard is tested against the SASKatchewan radiative TRANsfer (SASKTRAN) algorithm. The retrieved ozone profiles from each of these algorithms are evaluated with ozone profiles from both ozonesondes and the Aura Microwave Limb Sounder (MLS). Effects on derived OMPS tropospheric ozone caused by the 2015-2016 El Nino event are highlighted. This recent El Nino produced anomalies in tropospheric ozone throughout the tropical Pacific involving increases of ~10 DU over Indonesia and decreases ~5-10 DU in the eastern Pacific. These changes in ozone due to El Nino were predominantly dynamically-induced, caused by the eastward shift in sea-surface temperature and convection from the western to the eastern Pacific.

  6. Highlights from the 11-Year Record of Tropospheric Ozone from OMI/MLS and Continuation of that Long Record Using OMPS Measurements

    NASA Technical Reports Server (NTRS)

    Ziemke, J. R.; Kramarova, N. A.; Bhartia, P. K.; Degenstein, D. A.; Deland, M. T.

    2016-01-01

    Since October 2004 the Ozone Monitoring Instrument (OMI) and Microwave Limb Sounder (MLS) onboard the Aura satellite have provided over 11 years of continuous tropospheric ozone measurements. These OMI/MLS measurements have been used in many studies to evaluate dynamical and photochemical effects caused by ENSO, the Madden-Julian Oscillation (MJO) and shorter timescales, as well as long-term trends and the effects of deep convection on tropospheric ozone. Given that the OMI and MLS instruments have now extended well beyond their expected lifetimes, our goal is to continue their long record of tropospheric ozone using recent Ozone Mapping Profiler Suite (OMPS) measurements. The OMPS onboard the Suomi National Polar-orbiting Partnership NPP satellite was launched on October 28, 2011 and is comprised of three instruments: the nadir mapper, the nadir profiler, and the limb profiler. Our study combines total column ozone from the OMPS nadir mapper with stratospheric column ozone from the OMPS limb profiler to measure tropospheric ozone residual. The time period for the OMPS measurements is March 2012 present. For the OMPS limb profiler retrievals, the OMPS v2 algorithm from Goddard is tested against the University of Saskatchewan (USask) Algorithm. The retrieved ozone profiles from each of these algorithms are evaluated with ozone profiles from both ozonesondes and the Aura Microwave Limb Sounder (MLS). Effects on derived OMPS tropospheric ozone caused by the 2015-2016 El Nino event are highlighted. This recent El Nino produced anomalies in tropospheric ozone throughout the tropical Pacific involving increases of approximately 10 DU over Indonesia and decreases approximately 5-10 DU in the eastern Pacific. These changes in ozone due to El Nino were predominantly dynamically-induced, caused by the eastward shift in sea-surface temperature and convection from the western to the eastern Pacific.

  7. Ten years of continuous monitoring of soil CO2 flux: results and implications from the first geochemical monitoring network on Mount Etna.

    NASA Astrophysics Data System (ADS)

    Liuzzo, Marco; Gurrieri, Sergio; Giuffrida, Giovanni; Gaetano, Giudice; Cappuzzo, Santino

    2013-04-01

    both volcanological and geophysical data puts the global soil CO2 flux trends into a coherent framework that further highlights how the time flux variations are closely related to volcanic activities. This insight into CO2 flux variations, based upon approximately 10 years of uninterrupted data, permit us to conclude that the continuous monitoring of volcanic soil degassing may facilitate the forecasting of imminent eruptive activity or the temporal evolution of an in-progress eruption and, therefore, play an important contributory role in the planning of Civil Defence actions in volcanic areas under high-hazard conditions.

  8. Clinical practice guidelines for posmenopausal, glucocorticoid-induced and male osteoporosis. Spanish Society for Research on Bone and Mineral Metabolism (3rd updated version 2014).

    PubMed

    González-Macías, J; Del Pino-Montes, J; Olmos, J M; Nogués, X

    2015-12-01

    These guidelines update issues covered in previous versions and introduce new ones that have arisen in recent years. The former refer mainly to the therapeutic developments that have been made during this time (zoledronate, denosumab, bazedoxifene), which have led to a change in the drug selection algorithm. The latter deal with therapeutic management, the description of new adverse effects (which have led to changes in therapeutic behaviour patterns, as is the case with atypical fracture of the femur), treatment duration (with consideration for the so-called "therapeutic holidays"), the so-called sequential treatment and changes in treatment imposed by certain circumstances. A new algorithm has been introduced for sequential treatment. Attention has also been paid to vertebroplasty and kyphoplasty. PMID:26434811

  9. Implementing efficient and sustainable collaboration between National Immunization Technical Advisory Groups: Report on the 3rd International Technical Meeting, Paris, France, 8-9 December 2014.

    PubMed

    Perronne, Christian; Adjagba, Alex; Duclos, Philippe; Floret, Daniel; Houweling, Hans; Le Goaster, Corinne; Lévy-Brühl, Daniel; Meyer, François; Senouci, Kamel; Wichmann, Ole

    2016-03-01

    NITAGs. NITAGs already collaborate at the global level via the NITAG Resource Centre, a web-based platform developed by the Health Policy and Institutional Development Unit (WHO Collaborating Centre) of the Agence de Médecine Préventive (AMP-HPID). It would be appropriate to continue facilitating the coordination of this global network through the AMP-HPID NITAG Resource Centre. (v) While sharing work products and experiences, each NITAG would retain responsibility for its own decision-making and country-specific recommendations. PMID:26859237

  10. Implementing efficient and sustainable collaboration between National Immunization Technical Advisory Groups: Report on the 3rd International Technical Meeting, Paris, France, 8-9 December 2014.

    PubMed

    Perronne, Christian; Adjagba, Alex; Duclos, Philippe; Floret, Daniel; Houweling, Hans; Le Goaster, Corinne; Lévy-Brühl, Daniel; Meyer, François; Senouci, Kamel; Wichmann, Ole

    2016-03-01

    NITAGs. NITAGs already collaborate at the global level via the NITAG Resource Centre, a web-based platform developed by the Health Policy and Institutional Development Unit (WHO Collaborating Centre) of the Agence de Médecine Préventive (AMP-HPID). It would be appropriate to continue facilitating the coordination of this global network through the AMP-HPID NITAG Resource Centre. (v) While sharing work products and experiences, each NITAG would retain responsibility for its own decision-making and country-specific recommendations.

  11. Increased rate of depression and psychosomatic symptoms in Jewish migrants from the post-Soviet-Union to Germany in the 3rd generation after the Shoa.

    PubMed

    Ullmann, E; Barthel, A; Licinio, J; Petrowski, K; Bornstein, S R; Strauß, B

    2013-03-12

    The mental health status of persons with Jewish background living in Germany is discussed with special regard to social exclusion like anti-Semitism and overprotective parental rearing behavior, as a transmissional factor of the KZ-Syndrome. These stressors are considered in the context of a higher risk for depression/fear and psychosomatic disorders and also abnormal cortisol levels. The present sample (N=89) is derived from the Jewish population currently living in the German region of Saxony aged between 17-36 years that emigrated from the post-Soviet-Union areas. The mean age was 22.9 years. Two questionnaires to detect psychosomatic symptoms (Giessen complaint list (GBB)-24, hospital anxiety and depression scale) and one questionnaire addressing parental rearing behavior (FEE) were employed. Comparisons were drawn with normative data from the literature about the German residential population. In addition, questions were asked concerning the experience of anti-Semitism in Germany and in the post-Soviet-Union areas. A higher prevalence of depression/fear (10.3% versus 18.2%) and psychosomatic symptoms (M=14.03 versus 17.8; t=2.42; P<0.05) was observed in Jewish migrants to Germany as compared with non-Jewish German residents. Furthermore, anti-Semitic experiences in Germany correlated positively with depression (r=0.293; P<0.01) and fear (r=0.254; P<0.05). The anti-Semitic experiences in the post-Soviet-Union areas also correlated positively with limb pain (r=0.41, P<0.01), fatigue symptoms (r=0.296, P<0.01) and psychocardial symptoms (r=0.219, P<0.05). It was also confirmed that the male respondents recalled a controlling and overprotecting maternal rearing behavior more frequently than the German standard random sample (M=15.39 versus 18.6; t=2.68; P<0.01). The latter also correlated significantly positive with epigastric pain (r=0.349; P<0.01). The present results show that depression, fear and psychosomatic problems are common in Jewish residents with a

  12. Increased rate of depression and psychosomatic symptoms in Jewish migrants from the post-Soviet-Union to Germany in the 3rd generation after the Shoa

    PubMed Central

    Ullmann, E; Barthel, A; Licinio, J; Petrowski, K; Bornstein, S R; Strauß, B

    2013-01-01

    The mental health status of persons with Jewish background living in Germany is discussed with special regard to social exclusion like anti-Semitism and overprotective parental rearing behavior, as a transmissional factor of the KZ-Syndrome. These stressors are considered in the context of a higher risk for depression/fear and psychosomatic disorders and also abnormal cortisol levels. The present sample (N=89) is derived from the Jewish population currently living in the German region of Saxony aged between 17–36 years that emigrated from the post-Soviet-Union areas. The mean age was 22.9 years. Two questionnaires to detect psychosomatic symptoms (Giessen complaint list (GBB)-24, hospital anxiety and depression scale) and one questionnaire addressing parental rearing behavior (FEE) were employed. Comparisons were drawn with normative data from the literature about the German residential population. In addition, questions were asked concerning the experience of anti-Semitism in Germany and in the post-Soviet-Union areas. A higher prevalence of depression/fear (10.3% versus 18.2%) and psychosomatic symptoms (M=14.03 versus 17.8; t=2.42; P<0.05) was observed in Jewish migrants to Germany as compared with non-Jewish German residents. Furthermore, anti-Semitic experiences in Germany correlated positively with depression (r=0.293; P<0.01) and fear (r=0.254; P<0.05). The anti-Semitic experiences in the post-Soviet-Union areas also correlated positively with limb pain (r=0.41, P<0.01), fatigue symptoms (r=0.296, P<0.01) and psychocardial symptoms (r=0.219, P<0.05). It was also confirmed that the male respondents recalled a controlling and overprotecting maternal rearing behavior more frequently than the German standard random sample (M=15.39 versus 18.6; t=2.68; P<0.01). The latter also correlated significantly positive with epigastric pain (r=0.349; P<0.01). The present results show that depression, fear and psychosomatic problems are common in Jewish residents with a

  13. Increased rate of depression and psychosomatic symptoms in Jewish migrants from the post-Soviet-Union to Germany in the 3rd generation after the Shoa.

    PubMed

    Ullmann, E; Barthel, A; Licinio, J; Petrowski, K; Bornstein, S R; Strauß, B

    2013-01-01

    The mental health status of persons with Jewish background living in Germany is discussed with special regard to social exclusion like anti-Semitism and overprotective parental rearing behavior, as a transmissional factor of the KZ-Syndrome. These stressors are considered in the context of a higher risk for depression/fear and psychosomatic disorders and also abnormal cortisol levels. The present sample (N=89) is derived from the Jewish population currently living in the German region of Saxony aged between 17-36 years that emigrated from the post-Soviet-Union areas. The mean age was 22.9 years. Two questionnaires to detect psychosomatic symptoms (Giessen complaint list (GBB)-24, hospital anxiety and depression scale) and one questionnaire addressing parental rearing behavior (FEE) were employed. Comparisons were drawn with normative data from the literature about the German residential population. In addition, questions were asked concerning the experience of anti-Semitism in Germany and in the post-Soviet-Union areas. A higher prevalence of depression/fear (10.3% versus 18.2%) and psychosomatic symptoms (M=14.03 versus 17.8; t=2.42; P<0.05) was observed in Jewish migrants to Germany as compared with non-Jewish German residents. Furthermore, anti-Semitic experiences in Germany correlated positively with depression (r=0.293; P<0.01) and fear (r=0.254; P<0.05). The anti-Semitic experiences in the post-Soviet-Union areas also correlated positively with limb pain (r=0.41, P<0.01), fatigue symptoms (r=0.296, P<0.01) and psychocardial symptoms (r=0.219, P<0.05). It was also confirmed that the male respondents recalled a controlling and overprotecting maternal rearing behavior more frequently than the German standard random sample (M=15.39 versus 18.6; t=2.68; P<0.01). The latter also correlated significantly positive with epigastric pain (r=0.349; P<0.01). The present results show that depression, fear and psychosomatic problems are common in Jewish residents with a

  14. Learning difficulties: a retrospective study of their co morbidity and continuity as indicators of adult criminal behaviour in 18-70-year-old prisoners.

    PubMed

    Zakopoulou, Victoria; Pashou, Theodora; Tzavelas, Panagiotis; Christodoulides, Pavlos; Anna, Milona; Iliana, Kolotoura

    2013-11-01

    The development of learning difficulties is associated with problems in external (executive) and extensive behaviour in a co-occurrence with psycho-emotional problems beginning from pre-school, school age, and adolescence up to adulthood. Through the current survey, we aim to emphasise the early role of learning difficulties during the school age and adolescence of prisoners and their effects on the onset of offending behaviours in adulthood, such as criminal behaviour. Altogether, we studied 117 Greek adult prisoners from 18 to 70 years old who were accused of different types or degrees of offences. Through statistical analyses, the following factors were observed with high statistical significance as early indicators of criminal behaviour in the adult lives of the prisoners: (i) learning difficulties, (ii) family problems, (iii) behaviour disorders, (iv) developmental disorders, and (v) psycho-emotional disorders. As a result, the learning difficulties were assumed to be the most decisive factor in the developmental progression of prisoners because they manifested early in the prisoners' lives, weakened the prisoners to be competitive and robust, provoked a bad self-image and low self-esteem, and, in the frame of a weak or negative family and educational environment, they accompanied antisocial behaviour and psycho-emotional disorders even from adolescence, which continued into adulthood.

  15. The reconstruction of the first copper-smelting processes in Europe during the 4th and the 3rd millennium BC: where does the oxygen come from?

    NASA Astrophysics Data System (ADS)

    Burger, E.; Bourgarit, D.; Wattiaux, A.; Fialin, M.

    2010-09-01

    From the end of Chalcolithic times (end of the 4th millennium BC) up to the end of the Bronze Age (1st millenium BC), copper production increases dramatically in Western Europe. However, due to the scarcity of technology-related archaeological data, the technological background sustaining the transition to mass production modes remains poorly understood. The main archaeological clues concerning metal production stem from the metallurgical waste, namely copper slags. Those complex materials may be a genuine chemical footprint of the process. In particular, it may bring new insights on one main issue of the process reconstruction: the origin of the oxygen in the system. A new analytical methodology based on both mass-balance calculation and quantification of Fe3+ contents in copper slags (Mössbauer spectroscopy, electronic microprobe and Synchrotron μ-XANES at the Fe-K-edge) has been set up. This methodology enables us to distinguish between the solid and gaseous sources of oxygen in a broad range of working conditions, thus yielding new features for the understanding of the first smelting processes dealing with copper sulphides in Western Europe 4000 years ago.

  16. Mixing and turbulent mixing in fluids, plasma and materials: summary of works presented at the 3rd International Conference on Turbulent Mixing and Beyond

    NASA Astrophysics Data System (ADS)

    Gauthier, Serge; Keane, Christopher J.; Niemela, Joseph J.; Abarzhi, Snezhana I.

    2013-07-01

    Mixing and turbulent mixing are non-equilibrium processes that occur in a broad variety of processes in fluids, plasmas and materials. The processes can be natural or artificial, their characteristic scales can be astrophysical or atomistic, and energy densities can be low or high. Understanding the fundamental aspects of turbulent mixing is necessary to comprehend the dynamics of supernovae and accretion discs, stellar non-Boussinesq and magneto-convection, mantle-lithosphere tectonics and volcanic eruptions, atmospheric and oceanographic flows in geophysics, and premixed and non-premixed combustion. It is crucial for the development of the methods of control in technological applications, including mixing mitigation in inertial confinement and magnetic fusion, and mixing enhancement in reactive flows, as well as material transformation under the action of high strain rates. It can improve our knowledge of realistic turbulent processes at low energy density involving walls, unsteady transport, interfaces and vortices, as well as high energy density hydrodynamics including strong shocks, explosions, blast waves and supersonic flows. A deep understanding of mixing and turbulent mixing requires one to go above and beyond canonical approaches and demands further enhancements in the quality and information capacity of experimental and numerical data sets, and in the methods of theoretical analysis of continuous dynamics and kinetics. This has the added potential then of bringing the experiment, numerical modelling, theoretical analysis and data processing to a new level of standards. At the same time, mixing and turbulent mixing being one of the most formidable and multi-faceted problems of modern physics and mathematics, is well open for a curious mind. In this article we briefly review various aspects of turbulent mixing, and present a summary of over 70 papers that were discussed at the third International Conference on 'Turbulent Mixing and Beyond', TMB-2011, that

  17. Multiple scales of temporal variability in ecosystem metabolism rates: results from two years of continuous monitoring in a forested headwater stream

    SciTech Connect

    Roberts, Brian J; Mulholland, Patrick J; Hill, Walter

    2007-01-01

    Headwater streams are key sites of nutrient and organic matter processing and retention, but little is known about temporal variability in gross primary production (GPP) and ecosystem respiration (ER) rates as a result of the short duration of most ecosystem metabolism measurements in lotic ecosystems. We examined temporal variability and controls on ecosystem metabolism by measuring daily rates continuously for two years in Walker Branch, a first-order deciduous forest stream. Four important scales of temporal variability in ecosystem metabolism rates were identified: (1) seasonal, (2) day-to-day, (3) episodic (storm-related), and (4) inter-annual. Seasonal patterns were largely controlled by the leaf phenology and productivity of the deciduous riparian forest. Walker Branch was strongly net heterotrophic throughout the year with the exception of the open-canopy spring when GPP and ER rates were similar. Day-to-day variability in weather conditions influenced light reaching the streambed, resulting in high day-to-day variability in GPP particularly during spring (daily light levels explained 84% of the variance in daily GPP in April). Episodic storms depressed GPP for several days in spring, but increased GPP in autumn by removing leaves shading the streambed. Storms depressed ER initially, but then stimulated ER to 2-3 times pre-storm levels for several days. Walker Branch was strongly net heterotrophic in both years of the study (NEP = -1156 and -773 g O2 m-2 y-1), with annual GPP being similar (488 and 519 g O2 m-2 y-1) but annual ER being higher in 2004 than 2005 (-1645 vs. -1292 g O2 m-2 y-1). Inter-annual variability in ecosystem metabolism (assessed by comparing 2004 and 2005 rates with previous measurements) was the result of the storm frequency and timing and the size of the spring macroalgal bloom. Changes in local climate can have substantial impacts on stream ecosystem metabolism rates and ultimately influence the carbon source and sink properties of

  18. NEPTUNE Canada Regional Cabled Ocean Observatory Network: Scientific results across the earth/ocean sciences from two years of continuous real-time data.

    NASA Astrophysics Data System (ADS)

    Best, M.; Johnson, F.; Moran, K.; Pirenne, B.; Founding Scientists Of Neptune Canada

    2011-12-01

    NEPTUNE Canada completed the installation and is now operating an 800 km, 5-node, regional cabled ocean network that spans the northern Juan de Fuca tectonic plate and continental shelf/slope in the northeastern Pacific. The NEPTUNE Canada network is part of the Ocean Networks Canada Observatory. Public data flow started in 2009 and interactive instruments continue to be added to this technically advanced system which provides continuous power and high bandwidth for enabling the collection of real-time physical, chemical, geological, and biological oceanographic data at resolutions relevant for furthering our understanding of the dynamics of the earth-ocean system. Here we present an overview and some initial results of the early installed real-time experiments, developed through workshops and international competitions, at five offshore locations. Inshore at Folger Passage, Barkley Sound, observations are focused on understanding biological productivity and the effects that marine processes have on fish and marine mammals. Experiments around Barkley Canyon allow quantification of changes in benthic activity with nutrient and sediment transport. There and north along the mid-continental slope near ODP Site 889, instruments are monitoring changes in the distribution, structure, related biotas and venting of gas hydrates. A Circulation Obviation Retrofit Kit (CORK) at our mid-plate site (ODP 1026) monitors real-time changes in crustal temperature and pressure, particularly related to events such as earthquakes, tsunamis, hydrothermal convection; these data are also important for understanding regional plate strain. At Endeavour on the Juan de Fuca Ridge, complex interactions among volcanic, tectonic, hydrothermal and biological processes are being observed. Across the NEPTUNE Canada network, high resolution acoustic and seismic monitoring elucidates tectonic processes such as earthquakes, and a tsunami detection system allows for the determination of open ocean

  19. Establishing a Long-term 30 Year Global Solar Resource at 10 km Resolution: Preliminary Results From Test Processing and Continuing Plans

    NASA Astrophysics Data System (ADS)

    Stackhouse, P. W.; Mikovitz, J. C.; Cox, S. J.; Zhang, T.; Perez, R.; Schlemmer, J.; Sengupta, M.; Knapp, K. R.

    2014-12-01

    As renewable energy system become more prevalent, improved global long-term, up-to-date records are needed to better understand and quantify the solar resource and variability. Toward this end, a project involving NASA, DOE NREL, SUNY-Albany and the NOAA National Climatic Data Center (NCDC) was initiated to provide NREL with a solar resource mapping production system for improved depiction of global long-term solar resources that provides the capacity for continual updates. This new production system is made possible by the efforts of NOAA and NASA to completely reprocess the International Satellite Cloud Climatology Project (ISCCP) data set that provides satellite visible and infrared radiances together with retrieved cloud and surface properties on a 3-hourly basis beginning from July 1983 at an effective 10 km resolution. Thus, working with SUNY and NCDC, NASA will develop and test an improved production system that will yield an operational production system for NREL to continually update the Earth's solar resource. In this presentation, we provide a general overview of this project together with samples of the new solar irradiance mapped data products and comparisons to surface measurements at various locations across the world. Here, a three-year prototype of the anticipated ISCCP data set called GridSat is used to assess the algorithms and demonstrate the production system. GridSat maps together cross-calibrated visible and IR reflectances from all the world's geosynchronous satellites at 10 km and 3-hourly respectively. The results are shown and discussed in comparison to existing solar data products. Additionally, the solar irradiance values are compared to various Baseline Surface Radiation Network surface site measurements and other high quality surface measurements. The statistics of the agreement between the measurements and new satellite estimates are also reviewed. The team is now testing a beta release of the revised ISCCP data set through the NOAA

  20. Mixing and turbulent mixing in fluids, plasma and materials: summary of works presented at the 3rd International Conference on Turbulent Mixing and Beyond

    NASA Astrophysics Data System (ADS)

    Gauthier, Serge; Keane, Christopher J.; Niemela, Joseph J.; Abarzhi, Snezhana I.

    2013-07-01

    Mixing and turbulent mixing are non-equilibrium processes that occur in a broad variety of processes in fluids, plasmas and materials. The processes can be natural or artificial, their characteristic scales can be astrophysical or atomistic, and energy densities can be low or high. Understanding the fundamental aspects of turbulent mixing is necessary to comprehend the dynamics of supernovae and accretion discs, stellar non-Boussinesq and magneto-convection, mantle-lithosphere tectonics and volcanic eruptions, atmospheric and oceanographic flows in geophysics, and premixed and non-premixed combustion. It is crucial for the development of the methods of control in technological applications, including mixing mitigation in inertial confinement and magnetic fusion, and mixing enhancement in reactive flows, as well as material transformation under the action of high strain rates. It can improve our knowledge of realistic turbulent processes at low energy density involving walls, unsteady transport, interfaces and vortices, as well as high energy density hydrodynamics including strong shocks, explosions, blast waves and supersonic flows. A deep understanding of mixing and turbulent mixing requires one to go above and beyond canonical approaches and demands further enhancements in the quality and information capacity of experimental and numerical data sets, and in the methods of theoretical analysis of continuous dynamics and kinetics. This has the added potential then of bringing the experiment, numerical modelling, theoretical analysis and data processing to a new level of standards. At the same time, mixing and turbulent mixing being one of the most formidable and multi-faceted problems of modern physics and mathematics, is well open for a curious mind. In this article we briefly review various aspects of turbulent mixing, and present a summary of over 70 papers that were discussed at the third International Conference on 'Turbulent Mixing and Beyond', TMB-2011, that

  1. Maintenance of Efficacy and Continuing Safety of Golimumab for Active Ulcerative Colitis: PURSUIT-SC Maintenance Study Extension Through 1 Year

    PubMed Central

    Gibson, Peter R; Feagan, Brian G; Sandborn, William J; Marano, Colleen; Strauss, Richard; Johanns, Jewel; Padgett, Lakshmi; Collins, Judith; Tarabar, Dino; Hebzda, Zbigniew; Rutgeerts, Paul; Reinisch, Walter

    2016-01-01

    Objectives: The safety and efficacy of subcutaneous golimumab through 2 years of maintenance therapy was evaluated in patients with moderate-to-severe ulcerative colitis (UC). Methods: Patients completing treatment through week 52 (placebo, golimumab 50, 100, every-4-weeks (q4w)) and evaluations at week 54 were eligible for this long-term extension (LTE) trial. Patients receiving placebo or golimumab 50 mg with worsening disease during the LTE could receive golimumab 100 mg. Efficacy assessments included the Mayo physician's global assessment (PGA) subscore, inflammatory bowel disease questionnaire (IBDQ), and corticosteroid use. Patients who were randomized to golimumab at PURSUIT-Maintenance baseline and continued receiving golimumab during the LTE were analyzed for efficacy (using intention-to-treat and “as observed” analyses; N=195) and safety (N=200). Patients treated with golimumab at any time from induction baseline through week 104 (N=1240) constituted the overall safety population. Results: Baseline demographics and disease characteristics of patients entering the LTE receiving golimumab were similar to those of all patients randomized to golimumab maintenance at baseline. At week 104, 80.5% (157/195) of patients had a PGA=0/1 (range weeks 56–104: 80.5–91.8%) and 56.4% (110/195) had a PGA=0 (weeks 56–104: range: 53.8–58.5%). Through week 104, 86% of patients maintained inactive or mild disease activity. Among 174 corticosteroid-free patients at week 54, 88.5% remained corticosteroid-free at week 104. At week 104, 62.2% (120/193) had an IBDQ score ≥170. Tuberculosis, opportunistic infection, and malignancy rates were low, and the overall safety profile was similar to that reported through week 54. Two non-melanoma skin cancers, one metastatic colon cancer, and two deaths (biventricular heart dysfunction, sepsis) occurred between weeks 54 and 104. Conclusion: Subcutaneous golimumab q4w through 2 years maintained clinical benefit and reduced

  2. Ten years of continuous observations of stratospheric ozone depleting gases at Monte Cimone (Italy)--comments on the effectiveness of the Montreal Protocol from a regional perspective.

    PubMed

    Maione, M; Giostra, U; Arduini, J; Furlani, F; Graziosi, F; Lo Vullo, E; Bonasoni, P

    2013-02-15

    Halogenated gases potentially harmful to the stratospheric ozone layer are monitored worldwide in order to assess compliance with the Montreal Protocol requiring a phase out of these compounds on a global scale. We present the results of long term (2002-2011) continuous observation conducted at the Mt. Cimone GAW Global Station located on the highest peak of the Italian Northern Apennines, at the border of two important regions: the Po Valley (and the Alps) to the North and the Mediterranean Basin to the South. Bi-hourly air samples of CFC-12, CFC-11, CFC-114, CFC-115, H-1211, H-1301, methyl chloroform, carbon tetrachloride, HCFC-22, HCFC-142b, HCFC-124 and methyl bromide are collected and analysed using a gas chromatograph-mass spectrometer, providing multi annual time series. In order to appreciate the effectiveness of the Montreal Protocol from a regional perspective, trends and annual growth rates of halogenated species have been calculated after identification of their baseline values. A comparison with results from other international observation programmes is also presented. Our data show that the peak in the atmospheric mixing ratios of four chlorofluorocarbons, two halons and two chlorocarbons has been reached and all these species now show a negative atmospheric trend. Pollution episodes are still occurring for species like halon-1211, methyl chloroform and carbon tetrachloride, indicating fresh emissions from the site domain which could be ascribed both to fugitive un-reported uses of the compounds and/or emissions from banks. For the hydrofluorocarbons changes in the baseline are affected by emissions from fast developing Countries in East Asia. Fresh emissions from the site domain are clearly declining. Methyl bromide, for which the Mediterranean area is an important source region, shows, in a generally decreasing trend, an emission pattern that is not consistent with the phase-out schedule of this compound, with a renewed increase in the last two

  3. Ten years of continuous observations of stratospheric ozone depleting gases at Monte Cimone (Italy)--comments on the effectiveness of the Montreal Protocol from a regional perspective.

    PubMed

    Maione, M; Giostra, U; Arduini, J; Furlani, F; Graziosi, F; Lo Vullo, E; Bonasoni, P

    2013-02-15

    Halogenated gases potentially harmful to the stratospheric ozone layer are monitored worldwide in order to assess compliance with the Montreal Protocol requiring a phase out of these compounds on a global scale. We present the results of long term (2002-2011) continuous observation conducted at the Mt. Cimone GAW Global Station located on the highest peak of the Italian Northern Apennines, at the border of two important regions: the Po Valley (and the Alps) to the North and the Mediterranean Basin to the South. Bi-hourly air samples of CFC-12, CFC-11, CFC-114, CFC-115, H-1211, H-1301, methyl chloroform, carbon tetrachloride, HCFC-22, HCFC-142b, HCFC-124 and methyl bromide are collected and analysed using a gas chromatograph-mass spectrometer, providing multi annual time series. In order to appreciate the effectiveness of the Montreal Protocol from a regional perspective, trends and annual growth rates of halogenated species have been calculated after identification of their baseline values. A comparison with results from other international observation programmes is also presented. Our data show that the peak in the atmospheric mixing ratios of four chlorofluorocarbons, two halons and two chlorocarbons has been reached and all these species now show a negative atmospheric trend. Pollution episodes are still occurring for species like halon-1211, methyl chloroform and carbon tetrachloride, indicating fresh emissions from the site domain which could be ascribed both to fugitive un-reported uses of the compounds and/or emissions from banks. For the hydrofluorocarbons changes in the baseline are affected by emissions from fast developing Countries in East Asia. Fresh emissions from the site domain are clearly declining. Methyl bromide, for which the Mediterranean area is an important source region, shows, in a generally decreasing trend, an emission pattern that is not consistent with the phase-out schedule of this compound, with a renewed increase in the last two

  4. A 9-year continuous monitoring of salinity in the Gironde estuary (S-W France) reveals marked inter-annual variability in marine intrusion

    NASA Astrophysics Data System (ADS)

    Schmidt, Sabine; Sottolichio, Aldo

    2013-04-01

    Estuaries form a transition zone in which rivers and oceans meet, including both fresh and salt waters. Thus conditions in estuary are more variable than those in either rivers or marine environments. In particular salinity presents a large temporal and lateral variations, depending of the degree of water mixing. The limit of salinity intrusion along an estuary is determined by the balance between the landward transport of salt by tidal processes and its seaward return by freshwater discharges. The major factor that affects the limit of saline intrusion along an estuary is freshwater inflow. In a context of global change, salinity intrusion in estuaries is expected to increase due to the cumulative effect of decrease in freshwater flows (changes in rain rate, decrease of riverine discharge due to upstream land use) and to sea level rives. At present, it is still difficult to establish changes in marine intrusion in estuaries due to the limited available data set. With its 625 km2, the Gironde estuary (S-W France) is one of the largest European estuaries. Since 2004, a real-time continuous system (MAGEST network) records four selected parameters (salinity, turbidity, dissolved oxygen) to establish a reference database of water-quality of this fluvio-estuarine system to address current and future water-quality issues. Here we present in details the 9-year time series of salinity in the Gironde estuary, recorded at four stations representative of the central and up estuary. Not surprisingly there are large difference among the four instrumented stations depending on their localization. But the time-series had allowed to highlight marked inter-annual variability in relation with the local hydrology. This example clearly illustrates the interest of long-term time series to detect potential changes in salinity, related to global changes, from inter-annual variability.

  5. Economic Evaluation of Endoscopic Sinus Surgery versus Continued Medical Therapy for Refractory Chronic Rhinosinusitis

    PubMed Central

    Rudmik, Luke; Soler, Zachary M.; Mace, Jess C.; Schlosser, Rodney J.; Smith, Timothy L.

    2014-01-01

    Objective To evaluate the long-term cost-effectiveness of endoscopic sinus surgery (ESS) compared to continued medical therapy for patients with refractory chronic rhinosinusitis (CRS). Study Design Cohort-style Markov decision tree economic evaluation Methods The economic perspective was the US third party payer with a 30 year time horizon. The two comparative treatment strategies were: 1) ESS followed by appropriate postoperative medical therapy and 2) continued medical therapy alone. Primary outcome was the incremental cost per quality adjusted life year (QALY). Costs were discounted at a rate of 3.5% in the reference case. Multiple sensitivity analyses were performed including differing time-horizons, discounting scenarios, and a probabilistic sensitivity analysis (PSA). Results The reference case demonstrated that the ESS strategy cost a total of $48,838.38 and produced a total of 20.50 QALYs. The medical therapy alone strategy cost a total of $28,948.98 and produced a total of 17.13 QALYs. The incremental cost effectiveness ratio (ICER) for ESS versus medical therapy alone is $5,901.90 per QALY. The cost-effectiveness acceptability curve from the PSA demonstrated that there is 74% certainty that the ESS strategy is the most cost-effective decision for any willingness to pay threshold greater then $25,000. The time horizon analysis suggests that ESS becomes the cost-effective intervention within the 3rd year after surgery. Conclusion Results from this study suggest that employing an ESS treatment strategy is the most cost-effective intervention compared to continued medical therapy alone for the long-term management of patients with refractory CRS. PMID:25186499

  6. Radiation Therapy Physics, 3rd Edition

    NASA Astrophysics Data System (ADS)

    Hendee, William R.; Ibbott, Geoffrey S.; Hendee, Eric G.

    2004-08-01

    The Third Edition of Radiation Therapy Physics addresses in concise fashion the fundamental diagnostic radiologic physics principles as well as their clinical implications. Along with coverage of the concepts and applications for the radiation treatment of cancer patients, the authors have included reviews of the most up-to-date instrumentation and critical historical links. The text includes coverage of imaging in therapy planning and surveillance, calibration protocols, and precision radiation therapy, as well as discussion of relevant regulation and compliance activities. It contains an updated and expanded section on computer applications in radiation therapy and electron beam therapy, and features enhanced user-friendliness and visual appeal with a new, easy-to-follow format, including sidebars and a larger trim size. With its user-friendly presentation and broad, comprehensive coverage of radiotherapy physics, this Third Edition doubles as a medical text and handy professional reference.

  7. Coal mine ground control. 3rd ed.

    SciTech Connect

    Peng, S.S.

    2008-09-15

    The third edition not only completely revises and updates the original subject areas, but also is broadened to include a number of new topics such as high horizontal stresses, computer modeling, and highwall stability. The subject areas covered in this book define the current field of coal mine ground control, except for the recently emerging topic of mine seals and some conventional subjects such as coal/rock cutting and impoundment dams. It contains 1,134 references from all published sources, and archived since 1876.

  8. Cerebral computed tomography, 3rd Edition

    SciTech Connect

    Weisberg, L.; Nice, C.

    1988-01-01

    This book is an introduction to the utilization of computed tomography in evaluating patients with intracranial and orbital disorders. It features clinical correlations and provides an overview of general principles, performance, and normal anatomy of CT. It covers evaluation of specific neurologic signs and symptoms, including stroke, metastatic disease, increased intracranial pressure, head injury, pediatric conditions, and more.

  9. Teaching Visually Impaired Children. 3rd Edition

    ERIC Educational Resources Information Center

    Bishop, Virginia E.

    2004-01-01

    In this exceptional new third edition, the author has retained much of the practical "how to" approach of the previous editions, but adds depth in two dimensions: learning theory and the educational process. This book is "so comprehensive in scope and complete in detail that it would be the most likely recommended" (from the foreword by Dr.…

  10. Fundamentals of nuclear pharmacy, 3rd Ed

    SciTech Connect

    Saha, G.B. )

    1992-01-01

    This book is a standard text/reference of nuclear pharmacy. New sections in the Third Edition include: instruments used for radiation detection and measurement; disposal of radioactive materials; clinical uses of all new and existing radiopharmaceuticals; 99m Tc and 123I-labeled radiopharmaceuticals, as well as radiolabeled leukocytes, platelets, and antibodies; and up-to-date descriptions of the latest FDA regulations.

  11. The 3rd International Microgravity Combustion Workshop

    NASA Technical Reports Server (NTRS)

    Ross, Howard D. (Compiler)

    1995-01-01

    This Conference Publication contains 71 papers presented at the Third International Microgravity Combustion Workshop held in Cleveland, Ohio, from April 11 to 13, 1995. The purpose of the workshop was twofold: to exchange information about the progress and promise of combustion science in microgravity and to provide a forum to discuss which areas in microgravity combustion science need to be expanded profitably and which should be included in upcoming NASA Research Announcements (NRA).

  12. The Physics of Glaciers, 3rd Edition

    NASA Astrophysics Data System (ADS)

    Bahr, David

    At one time or another, who among us has not marveled at the beauty of the snow and ice-covered Alps, or admired the tenacity of polar explorers and the adventurous spirits of climbers on the glacier-clad summits of the high Himalaya? The fascination of distant ice covered expanses has enlisted more than a few recruits into the ranks of glaciologists, but many, if not most, of today's students of glaciology are a slightly less romantic and more mathematical lot, attracted by the quantitative world of physics and the applied sciences of polar climatology, ice mechanics, and snow hydrology.Once a relatively quiet branch of geophysics filled with venturesome climbers capable of reaching the objects of their study, glaciology is now a field that is fueled by a rapid influx of talent, technology, and new ideas due to the increasingly acknowledged relationships between global climate, sea level, and ice sheets. While the understanding of glacier processes has seen significant progress, as a result there is also a sense of being overwhelmed by the voluminous and sometimes speculative theories and field observations associated with an expanding discipline.

  13. A Beginning. Revised 3rd Edition.

    ERIC Educational Resources Information Center

    Healy, Mary K.; Root, Phyllis

    This document contains a selection of materials focusing on man acting to know, preserve, and improve his environment. The booklet is divided into three parts. Part one presents a listing of objectives. They reflect a need for all to become aware of the problems that plague our environment. Furthermore, they indicate that the ecological…

  14. 3rd Brazilian Consensus on Helicobacter pylori.

    PubMed

    Coelho, Luiz Gonzaga; Maguinilk, Ismael; Zaterka, Schlioma; Parente, José Miguel; do Carmo Friche Passos, Maria; Moraes-Filho, Joaquim Prado P

    2013-04-01

    Signicant progress has been obtained since the Second Brazilian Consensus Conference on Helicobacter pylori Infection held in 2004, in São Paulo, SP, Brazil, and justify a third meeting to establish updated guidelines on the current management of H. pylori infection. The Third Brazilian Consensus Conference on H pylori Infection was organized by the Brazilian Nucleus for the Study of Helicobacter, a Department of the Brazilian Federation of Gastroenterology and took place on April 12-15, 2011, in Bento Gonçalves, RS, Brazil. Thirty-one delegates coming from the five Brazilian regions and one international guest, including gastroenterologists, pathologists, epidemiologists, and pediatricians undertook the meeting. The participants were allocated in one of the five main topics of the meeting: H pylori, functional dyspepsia and diagnosis; H pylori and gastric cancer; H pylori and other associated disorders; H pylori treatment and retreatment; and, epidemiology of H pylori infection in Brazil. The results of each subgroup were submitted to a final consensus voting to all participants. Relevant data were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. Seventy per cent and more votes were considered as acceptance for the final statement. This article presents the main recommendations and conclusions to guide Brazilian doctors involved in the management of H pylori infection.

  15. Elementary Science Guide -- 3rd Grade.

    ERIC Educational Resources Information Center

    Wieland, Anne; And Others

    Presented is a resource book to be used with instructional kits for elementary school science students, grade 3. The individual units at this grade level are based on curriculum which has been developed by the National Science Foundation in the 1960s and revised to meet student and teacher identified needs in Anchorage, Alaska. Six units are…

  16. Lucky Guess or Knowledge: A Cross-Sectional Study Using the Bland and Altman Analysis to Compare Confidence-Based Testing of Pharmacological Knowledge in 3rd and 5th Year Medical Students

    ERIC Educational Resources Information Center

    Kampmeyer, Daniela; Matthes, Jan; Herzig, Stefan

    2015-01-01

    Multiple-choice-questions are common in medical examinations, but guessing biases assessment results. Confidence-based-testing (CBT) integrates indicated confidence levels. It has been suggested that correctness of and confidence in an answer together indicate knowledge levels thus determining the quality of a resulting decision. We used a CBT…

  17. Effect of Peers Assessment and Short Report in Year III Laboratory Course

    ERIC Educational Resources Information Center

    Rahman, Norliza Abd; Kofli, Noorhisham Tan

    2013-01-01

    Laboratory course in Biochemical and Chemical Engineering Programmes at the Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, has introduced the peer group evaluation, presentation, reports submitted by groups/individual as assessment tools for 3rd year laboratory course. The experiments for the course…

  18. 76 FR 799 - Publication of Year 2010 Form M-1 With Electronic Filing Option, Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... the EBSA toll-free publication hotline at 1-866-444-EBSA (3272). Questions on completing the form are... Benefits Security Administration Publication of Year 2010 Form M-1 With Electronic Filing Option, Notice... of Labor's Order 6-2009, 74 FR 21524 (May 7, 2009). Signed at Washington, DC this 3rd day of...

  19. The Longitudinal Relations of Teacher Expectations to Achievement in the Early School Years

    ERIC Educational Resources Information Center

    Hinnant, J. Benjamin; O'Brien, Marion; Ghazarian, Sharon R.

    2009-01-01

    There is relatively little research on the role of teacher expectations in the early school years or the importance of teacher expectations as a predictor of future academic achievement. The current study investigated these issues in the reading and mathematic domains for young children. Data from nearly 1,000 children and families at 1st, 3rd,…

  20. Remote sensing investigation into the correlation between landslides caused by the 2002 November 3rd, 7.9M Denali Fault earthquake and a surge of the SE fork of McGinnis Peak Glacier.

    NASA Astrophysics Data System (ADS)

    Benowitz, J.

    2007-12-01

    The 2002 November 3rd, 7.9 M Denali Fault caused a large landslide that deposited 11.4 x 106m3 feet of rock and ice onto the SE fork of McGinnis Peak Glacier. The landslide left a large mass on the upper ice reservoir of the glacier and blocked the terminus outlet of the glacier with debris. Satellite images and historic photos were used to examine the terminus history of the glacier. Further landslides/mass wasting events during the spring of 2003, documented via Land Sat 7 images, covered the same upper ice reservoir as the 2002 landslides. Between 2004 and 2006 the SE fork Glacier of McGinnis Peak experienced a dramatic surge. There is no known history of such dramatic surge occurrences on the glacier of interest. Though causation is difficult to prove preliminary evidence points towards the implication that the landslides generated by the 2002 earthquake most likely either caused or contributed to the documented glacial surge. Examination of more satellite images is planned to further examine McGinnis Peak's glacier history and to refine the timing of the possible correlation between the earthquake generated landslides and the dramatic surge of the SE glacial fork of McGinnis Peak

  1. New approaches, new activities and new outcomes in international conferences on HIV/AIDS in Africa--report of the 3rd African Conference on the Social Aspects of HIV/AIDS, Dakar, 10-14 October 2005.

    PubMed

    Niang, C I; Shisana, O; Andrews, G; Kaseje, D; Simbayi, L; Peltzer, K; Toefy, Y

    2006-08-01

    Africa's HIV/AIDS situation remains cause for concern. The impact of HIV is considerable and threatens the survival and development of African societies. Although much has been attempted, the results still leave much to be desired. AIDS is an epidemic that needs to be addressed with much creativity and spirit of initiative. It is against this background that the 3rd African conference on the social aspects of HIV/AIDS brought innovations in the way international conferences are designed, activities implemented and results obtained. The innovations concerned the approach to international conferences and take into account reconceptualising HIV/AIDS so as to encourage holistic approaches and better visibility of vulnerable groups. The activities of the conference were organised in such a way as to get people living with HIV/AIDS (PLWHA), grassroots communities and marginalised groups to play a focal role. The conference offered an opportunity for developing cultural activities that would translate the African cultural concepts that had been identified as important in the HIV situation and response analysis. Interaction at the conference created an opportunity to analyse the various dimensions of the political, cultural and economic determinants. The conference offered food for thought around response construction while singling out the themes of urgency and acceleration of response, synergy construction, and coordination and conception of political responses.

  2. Current practice of epidemiology in Africa: highlights of the 3rd conference of the African epidemiological association and 1st conference of the Cameroon society of epidemiology, Yaoundé, Cameroon, 2014

    PubMed Central

    Nkwescheu, Armand Seraphin; Fokam, Joseph; Tchendjou, Patrice; Nji, Akindeh; Ngouakam, Hermann; Andre, Bita Fouda; Joelle, Sobngwi; Uzochukwu, Benjamin; Akinroye, Kingsley; Mbacham, Wilfred; Colizzi, Vittorio; Leke, Rose; Victora, Cesar

    2015-01-01

    As the study of disease occurrence and health indicators in human populations, Epidemiology is a dynamic field that evolves with time and geographical context. In order to update African health workers on current epidemiological practices and to draw awareness of early career epidemiologists on concepts and opportunities in the field, the 3rd African Epidemiology Association and the 1st Cameroon Society of Epidemiology Conference was organized in June 2-6, 2014 at the Yaoundé Mont Febe Hotel, in Cameroon. Under the theme«Practice of Epidemiology in Africa: Stakes, Challenges and Perspectives», the conference attracted close to five hundred guest and participants from all continents. The two main programs were the pre-conference course for capacity building of African Early Career epidemiologists, and the conference itself, providing a forum for scientific exchanges on recent epidemiological concepts, encouraging the use of epidemiological methods in studying large disease burden and neglected tropical diseases; and highlighting existing opportunities. PMID:26523191

  3. The Efficacy of Incentives to Motivate Continued Fitness-Center Attendance in College First-Year Students: A Randomized Controlled Trial

    ERIC Educational Resources Information Center

    Pope, Lizzy; Harvey, Jean

    2014-01-01

    Objective: To determine whether fitness-center attendance established with the provision of weekly monetary incentives persisted after the discontinuation, or decreased frequency, of incentives. Participants: One hundred seventeen first-year college students participated during the 2011-2012 academic year. Methods: A randomized controlled trial…

  4. Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer

    PubMed Central

    Park, Ji Hyun; Choi, Yun Jung; Kim, Seon Ye; Lee, Jung-Eun; Sung, Ki Jung; Park, Sojung; Kim, Woo Sung; Song, Joon Seon; Choi, Chang-Min; Sung, Young Hoon; Rho, Jin Kyung; Lee, Jae Cheol

    2016-01-01

    Mutant-selective, 3rd-generation EGFR-TKIs were recently developed to control lung cancer cells harboring T790M-mediated resistance. However, the development of resistance to these novel drugs seems inevitable. Thus, we investigated the mechanism of acquired resistance to the mutant-selective EGFR-TKI WZ4002. We established five WZ4002-resistant cells, derived from cells harboring both EGFR and T790M mutations by long-term exposure to increasing doses of WZ4002. Compared with the parental cells, all resistant cells showed 10–100-folds higher resistance to WZ4002, as well as cross-resistance to other mutant-selective inhibitors. Among them, three resistant cells (HCC827/WR, PC-9/WR and H1975/WR) showed dependency on EGFR signaling, but two other cells (PC-9/GR/WR and PC-9/ER/WR) were not. Notably, insulin-like growth factor-1 receptor (IGF1R) was aberrantly activated in PC-9/GR/WR cells in phospho-receptor tyrosine kinase array, consistently accompanied by loss of IGF binding protein-3 (IGFBP3). Down-regulation of IGF1R by shRNA, as well as inhibition of IGF1R activity either by AG-1024 (a small molecule IGF1R inhibitor) or BI 836845 (a monoclonal anti-IGF1/2 blocking antibody), restored the sensitivity to WZ4002 both in vitro and xenograft. Taken together, these results suggest that activation of the IGF1R pathway associated with IGFBP3 loss can induce an acquired resistance to the mutant-selective EGFR-TKI, WZ4002. Therefore, a combined therapy of IGF1R inhibitors and mutant-selective EGFR-TKIs might be a viable treatment strategy for overcoming acquired resistance. PMID:26980747

  5. Continuous Problem of Function Continuity

    ERIC Educational Resources Information Center

    Jayakody, Gaya; Zazkis, Rina

    2015-01-01

    We examine different definitions presented in textbooks and other mathematical sources for "continuity of a function at a point" and "continuous function" in the context of introductory level Calculus. We then identify problematic issues related to definitions of continuity and discontinuity: inconsistency and absence of…

  6. Longitudinal Effects of a Two-Generation Preschool Programme on Receptive Language Skill in Low-Income Canadian Children to Age 10 Years

    ERIC Educational Resources Information Center

    Mughal, Muhammad Kashif; Ginn, Carla S.; Perry, Robert L.; Benzies, Karen M.

    2016-01-01

    We explored longitudinal effects of a two-generation preschool programme on receptive language scores in children (n = 78) at age 10 years, living with low income. Scores at four time-points, programme intake, exit, age 7, and age 10 years were measured using the "Peabody picture vocabulary test" (3rd ed.). Effects of culture…

  7. A Preliminary Investigation of Within-Year Growth Patterns in Reading and Mathematics Curriculum-Based Measures

    ERIC Educational Resources Information Center

    Graney, Suzanne B.; Missall, Kristen N.; Martinez, Rebecca S.; Bergstrom, Melissa

    2009-01-01

    This study examined patterns of growth across benchmark assessments for curriculum-based measures (CBM) over 2 academic years, with the twofold purpose of replicating earlier findings of growth patterns on R-CBM and conducting a preliminary investigation of growth patterns on M-CBM and CBM-Maze. The sample included 898 cases from 3rd through 5th…

  8. Year 3 Magnet Schools Assistance Program Annual Progress Report, 2009-10. E&R Report No. 10.09

    ERIC Educational Resources Information Center

    Brasfield, Jon; Cárdenas, Virginia

    2010-01-01

    The three Magnet Schools Assistance Program (MSAP) schools: East Garner International Baccalaureate Magnet Middle School (EGMMS), Garner International Baccalaureate Magnet High School (GMHS), and Southeast Raleigh Leadership and Technology Magnet High School (SRMHS) have shown progress on MSAP performance measures during the 3rd year of the grant.…

  9. Building from Yesterday to Tomorrow: The Continuing Federal Role in Indian Education. 15th Annual Report to the U.S. Congress, Fiscal Year 1988.

    ERIC Educational Resources Information Center

    National Advisory Council on Indian Education, Washington, DC.

    This report outlines the activities of the National Advisory Council on Indian Education (NACIE), and presents statistics and information on Indian schools and educational programs. Parts I and II describe NACIE and its functions and activities for fiscal year 1988--advising Congress on Indian education laws, reviewing applications for grants and…

  10. Living Our Mission, Building on Our Accomplishments: A Plan for Continued Change. 1994 Update. Five Year Strategic Plan, FY 1992-1996.

    ERIC Educational Resources Information Center

    Colorado State Dept. of Institutions, Denver. Div. of Developmental Disabilities.

    This report presents the 1994 update for a 5-year plan developed in 1992 which emphasizes changes resulting from restructuring Colorado state government and its departments. The first section presents the mission statement of the Division for Developmental Disabilities, a statement of the Division's operating principles, and a statement of desired…

  11. A STABLE ISOTOPE ANALYSIS OF SOIL CARBON DENSITY FRACTIONS FOLLOWING 4 YEARS OF CONTINUOUS CLIMATE CHANGE EXPOSURE IN A DOUGLAS FIR MESOCOSM STUDY

    EPA Science Inventory

    We conducted a 4-year full-factorial study of the effects of elevated atmospheric CO2 and temperature on Douglas fir seedlings growing in reconstructed native forest soils in mesocosms. The elevated CO2 treatment was ambient CO2 plus 200 ppm CO2. The elevated temperature treatm...

  12. The 1994 National Survey of Freshman Seminar Programs: Continuing Innovations in the Collegiate Curriculum. The Freshman Year Experience Monograph Series No. 20.

    ERIC Educational Resources Information Center

    Barefoot, Betsy O.; Fidler, Paul P.

    This monograph presents data from a 1994 national survey on freshman seminars gathered from 1,003 accredited, two- and four-year colleges with student populations of over 100 students. The survey investigated the content and structure of freshman seminars in a mail survey of provosts/vice presidents for academic affairs at 2,460 institutions Among…

  13. The Canadian Association for Adult Education in the Corbett Years: A Re-Evaluation. Occasional Papers in Continuing Education Number 20.

    ERIC Educational Resources Information Center

    Selman, Gordon R.

    This monograph deals with the philosophical and idealogical development of the Canadian Association for Adult Education (CAAE) during the years of Ned Corbett's leadership of the organization--from its founding in 1935 to his retirement in 1951. The first stage of transformation of the CAAE is discussed in terms of the association changing from a…

  14. PREFACE: Selected contributions from the 3rd Theory Meets Industry International Workshop, TMI2009 (Nagoya, Japan, 11-13 November 2009) Selected contributions from the 3rd Theory Meets Industry International Workshop, TMI2009 (Nagoya, Japan, 11-13 November 2009)

    NASA Astrophysics Data System (ADS)

    Tanaka, Isao; Hafner, Jürgen; Wimmer, Erich; Asahi, Ryoji

    2010-09-01

    The structures, physicochemical and thermodynamic properties of materials are becoming increasingly amenable to treatment by first-principles (ab initio) quantum mechanical simulations. Calculations containing a few hundred atoms are now routine, thanks to improvements in computer technology and computational techniques. Schemes to determine electronic structures more accurately and to treat more complex systems continue to be developed. A growing number of scientists and engineers are becoming aware of the power of these approaches. By applying these new computational tools, materials science and technology is expected to enter a new era of accelerated progress and efficiency. In 1998 the first workshop entitled 'Theory Meets Industry' (TMI) was held at the Vienna University of Technology. The aim of the workshop was to direct the potential of the ab initio simulation codes developed in academia towards the necessities arising from industrial research. Over the next decade, significant advances in ab initio methodology and its application to academic and industrial research were achieved. It was thus considered timely to hold a second TMI workshop in 2007, again in Vienna. The contributions from academia concentrated on a wide range of new developments in ab initio simulations, as well as on applications at the forefront of materials research. Speakers from the industrial sector also emphasized the progress made in successfully applying ab initiotechniques to key areas of modern technology. The proceedings were published in Journal of Physics: Condensed Matter as a special issue (volume 20, number 6, 2008), which was included in the 'Top papers 2008 showcase' of that journal. Following the notable success of the first two workshops, it was decided that the third TMI workshop would be held outside Europe. Holding the workshop in Japan was intended to increase awareness of theoretical materials science and foster further international collaboration in this field

  15. Continuous water-quality and suspended-sediment transport monitoring in the San Francisco Bay, California, water years 2011-13

    USGS Publications Warehouse

    Buchanan, Paul A.; Downing-Kunz, Maureen A.; Schoellhamer, David H.; Shellenbarger, Gregory; Weidich, Kurt W.

    2014-01-01

    The U.S. Geological Survey (USGS) monitors water quality and suspended-sediment transport in the San Francisco Bay. The San Francisco Bay area is home to millions of people, and the bay teems with both resident and migratory wildlife, plants, and fish. Fresh water mixes with salt water in the bay, which is subject both to riverine and marine (tides, waves, influx of salt water) influences. To understand this environment, the USGS, along with its partners, has been monitoring the bay’s waters continuously since 1988. Several water-quality variables are of particular importance to State and Federal resource managers and are monitored at key locations throughout the bay. Salinity, which indicates the relative mixing of fresh and ocean waters in the bay, is derived from specific conductance measurements. Water temperature, along with salinity, affects the density of water, which causes gravity driven circulation patterns and stratification in the water column. Turbidity is measured using light-scattering from suspended solids in water, and is used as a surrogate for suspended-sediment concentration (SSC). Suspended sediment often carries adsorbed contaminants; attenuates sunlight in the water column; deposits on tidal marsh and intertidal mudflats, which can help sustain these habitats as sea level rises; and deposits in ports and shipping channels, which can necessitate dredging. Dissolved oxygen, which is essential to a healthy ecosystem, is a fundamental indicator of water quality, and its concentration is affected by water temperature, salinity, ecosystem metabolism, tidal currents, and wind. Tidal currents in the bay reverse four times a day, and wind direction and intensity typically change on a daily cycle: consequently, salinity, water temperature, suspendedsediment concentration, and dissolvedoxygen concentration vary spatially and temporally throughout the bay, and continuous measurements are needed to observe these changes. The purpose of this fact sheet

  16. New archaeomagnetic data recovered from the study of celtiberic remains from central Spain (Numantia and Ciadueña, 3rd-1st centuries BC). Implications on the fidelity of the Iberian paleointensity database

    NASA Astrophysics Data System (ADS)

    Osete, M. L.; Chauvin, A.; Catanzariti, G.; Jimeno, A.; Campuzano, S. A.; Benito-Batanero, J. P.; Tabernero-Galán, C.; Roperch, P.

    2016-11-01

    Variations of geomagnetic field in the Iberian Peninsula prior to roman times are poorly constrained. Here we report new archaeomagnetic results from four ceramic collections and two combustion structures recovered in two pre-roman (celtiberic) archaeological sites in central Spain. The studied materials have been dated by archaeological evidences and supported by five radiocarbon dates. Rock magnetic experiments indicate that the characteristic remanent manetization (ChRM) is carried by a low coercivity magnetic phase with Curie temperatures of 530-575 °C, most likely Ti-poor titanomagnetite/titanomaghemite. Archaeointensity determinations were carried out by using the classical Thellier-Thellier protocol including tests and corrections for magnetic anisotropy and cooling rate dependency. Two magnetic behaviours were depicted during the laboratory treatment. Black potsherds and poor heated samples from the kilns, presented two magnetization components, alterations or curved Arai plots and were therefore rejected. In contrast, well heated specimens (red ceramic fragments and well heated samples from the kilns) show one single well defined component of magnetization going through the origin and linear Arai plots providing successful archaeointensity determinations. The effect of anisotropy of the thermoremanent magnetization (ATRM) on paleointensity analysis was systematically investigated obtaining very high ATRM corrections on fine pottery specimens. In some cases, differences between the uncorrected and ATRM corrected paleointensity values reached up to 86 %. The mean intensity values obtained from three selected set of samples were 64.3 ± 5.8 μT; 56.8 ± 3.8 and 56.7 ± 4.6 μT (NUS2, CI2 and CIA, respectively), which contribute to better understand the evolution of the palaeofield intensity in central Iberia during the 3rd-1st centuries BC. The direction of the field at first century BC has also been determined from oriented samples from CIA kilns (D = 357

  17. Combination therapy with bortezomib, continuous low-dose cyclophosphamide and dexamethasone followed by one year of maintenance treatment for relapsed multiple myeloma patients.

    PubMed

    de Waal, Esther G M; de Munck, Linda; Hoogendoorn, Mels; Woolthuis, Gerhard; van der Velden, Annette; Tromp, Yvonne; Vellenga, Edo; Hovenga, Sjoerd

    2015-12-01

    Combination therapy for longer periods but at low dose might be an effective and tolerable manner to treat patients with relapsed multiple myeloma (MM). We used bortezomib, dexamethasone and low-dose oral cyclophosphamide as an induction regimen, followed by 1 year of maintenance consisting of bortezomib and cyclophosphamide. Relapsed MM patients were treated with six cycles of bortezomib twice weekly, cyclophosphamide 50 mg daily and dexamethasone. Maintenance therapy was given for 1 year. Primary endpoints were toxicity during re-induction and maintenance therapy. Secondary endpoints were response to treatment and progression-free (PFS) and overall survival (OS). This study included 59 patients. Myelosuppression and neuropathy were the most common side effects. Median follow-up was 27·1 (0·46-54·4) months with an overall response of 71%, and a very good partial response or more of 33%. During maintenance, improved responsiveness was observed in 19% of the patients. The median PFS was 18·4 months (range 0·13-43·5) and the median OS was 28·1 months (range 0·13-54·4). In conclusion, our study demonstrates that treatment with bortezomib, dexamethasone and low-dose cyclophosphamide is an effective and manageable regimen. Adding 1 year of maintenance was feasible, with limited side effects and an increased response rate.

  18. The RAFT network: 5 years of distance continuing medical education and tele-consultations over the Internet in French-speaking Africa.

    PubMed

    Geissbuhler, Antoine; Bagayoko, Cheick Oumar; Ly, Ousmane

    2007-01-01

    Continuing education of healthcare professionals is a key element for the quality and efficiency of a health system. In developing countries, this activity is usually limited to capitals, and delocalized professionals do not have access to such opportunities, or to didactic material adapted to their needs. This limits the interest of such professionals to remain active in the periphery, where they are most needed to implement effective strategies for prevention and first-line healthcare. Telemedicine tools enable the communication and sharing of medical information in electronic form, and thus facilitate access to remote expertise. A physician located far from a reference center can consult its colleagues remotely in order to resolve a difficult case, follow a continuous education course over the Internet, or access medical information from digital libraries or knowledge bases. These same tools can also be used to facilitate exchanges between centers of medical expertise: health institutions of a same country as well as across borders. Since 2000, the Geneva University Hospitals have been involved in coordinating the development of a network for eHealth in Africa (the RAFT, Réseau en Afrique Francophone pour la Télémédecine), first in Mali, and now extending to 10 French-speaking African countries. The core activity of the RAFT is the webcasting of interactive courses. These sessions put the emphasis on knowledge sharing across care professionals, usually in the form of presentations and dialogs between experts in different countries. The technology used for the webcasting works with a slow (25 kbits/s) internet connection. Other activities of the RAFT network include visioconferences, teleconsultations based on the iPath system, collaborative knowledge bases development, support for medical laboratories quality control, and the evaluation of the use of telemedicine in rural areas (via satellite connections) in the context of multisectorial development. Finally

  19. The RAFT network: 5 years of distance continuing medical education and tele-consultations over the Internet in French-speaking Africa.

    PubMed

    Geissbuhler, Antoine; Bagayoko, Cheick Oumar; Ly, Ousmane

    2007-01-01

    Continuing education of healthcare professionals is a key element for the quality and efficiency of a health system. In developing countries, this activity is usually limited to capitals, and delocalized professionals do not have access to such opportunities, or to didactic material adapted to their needs. This limits the interest of such professionals to remain active in the periphery, where they are most needed to implement effective strategies for prevention and first-line healthcare. Telemedicine tools enable the communication and sharing of medical information in electronic form, and thus facilitate access to remote expertise. A physician located far from a reference center can consult its colleagues remotely in order to resolve a difficult case, follow a continuous education course over the Internet, or access medical information from digital libraries or knowledge bases. These same tools can also be used to facilitate exchanges between centers of medical expertise: health institutions of a same country as well as across borders. Since 2000, the Geneva University Hospitals have been involved in coordinating the development of a network for eHealth in Africa (the RAFT, Réseau en Afrique Francophone pour la Télémédecine), first in Mali, and now extending to 10 French-speaking African countries. The core activity of the RAFT is the webcasting of interactive courses. These sessions put the emphasis on knowledge sharing across care professionals, usually in the form of presentations and dialogs between experts in different countries. The technology used for the webcasting works with a slow (25 kbits/s) internet connection. Other activities of the RAFT network include visioconferences, teleconsultations based on the iPath system, collaborative knowledge bases development, support for medical laboratories quality control, and the evaluation of the use of telemedicine in rural areas (via satellite connections) in the context of multisectorial development. Finally

  20. Verification of Green's Function Approximation from Ambient Noise Cross-correlation using Three-year Continuous Seismic Data in South Niigata Prefecture, Japan

    NASA Astrophysics Data System (ADS)

    Hayashida, T.; Yoshimi, M.

    2015-12-01

    A continuous broadband-to-strong motion observation network that consists of 15 stations has been in operation since September 2011 in south Niigata Prefecture (Yoshimi et al., 2012). We applied seismic interferometry to the ambient noise data for the purpose of validating three-dimensional S-wave velocity structure (deep sedimentary structure) models beneath the observation area (Hayashida and Yoshimi, 2012, 2015). We used 37-month ambient noise data (October 2011 - October 2014) to obtain nine component (RR, TT, ZZ, RT, TR, ZR, ZT, RZ, and TZ) cross-correlation functions between two stations (105 station pairs) for distances from 4.3 to 40.7 km, according to the signal processing technique by Bensen et al. (2007). Our results show that signal-to-noise ratios (SNRs) of cross-correlation functions increase logarithmically as the stacking number increase and the wave trains are clear especially for TT and ZZ correlations. Some station pairs show large SNRs even for RT and TR correlations, indicating complicated velocity structure beneath the area. To extract Rayleigh-wave Green's functions efficiently, we applied body and surface wave separation technique by Takagi et al. (2014). We obtained clear dispersion curves of Rayleigh and Love waves in the frequency range between 0.1 and 1.0 Hz that correspond well to theoretical curves from existing velocity structure model of Sekiguchi et al. (2009). We found that maximum detectable wavelength of surface wave is nearly equivalent to station-to-station distance for near station pairs (< 20 km), whereas the maximum wavelength is about a half of station-to-station distance for further station pairs. We also investigated the effectiveness of uniform noise source distribution assumptions by comparing hourly stacked complex coherence functions of ambient noise between neighboring two stations and theoretical Bessel functions of the of first kind of zero order with the existing crustal (Takeda et al., 2012) and deep sedimentary

  1. Three years of liraglutide treatment offers continuously optimal glycemic control in a pediatric patient with maturity-onset diabetes of the young type 3.

    PubMed

    Urakami, Tatsuhiko; Habu, Masako; Okuno, Misako; Suzuki, Junichi; Takahashi, Shori; Yorifuji, Tohru

    2015-03-01

    Sulfonylureas (SUs) are recommended as the first-line pharmacological treatment in patients with uncontrolled maturity-onset diabetes of the young type 3 (MODY3). In contrast, glucagon-like peptide-1 (GLP-1) receptor agonists have the advantages of a low risk of hypoglycemia and maintained β-cell function. We report a pediatric patient with MODY3 treated with a GLP-1 receptor agonist, liraglutide. A 12-year-old Japanese girl with MODY3 had been treated with insulin for 6 months since the time of diagnosis. After genetic analysis, we switched her treatment from insulin to liraglutide. After switching to liraglutide, the patient maintained optimal glycemic control with hemoglobin A₁c levels of 6.8%-7.5% and had postprandial C-peptide levels >3.0 ng/mL during a 3-year treatment period. No adverse events associated with liraglutide were observed. GLP-1 receptor agonists are the potential medications for patients with MODY3 who maintain residual insulin secretion. PMID:25332292

  2. Carbon and Nitrogen Mineralization in Relation to Soil Particle-Size Fractions after 32 Years of Chemical and Manure Application in a Continuous Maize Cropping System

    PubMed Central

    Shao, Xingfang; Zhu, Ping; Zhang, Wenju; Xu, Minggang; Murphy, Daniel V.

    2016-01-01

    Long-term manure application is recognized as an efficient management practice to enhance soil organic carbon (SOC) accumulation and nitrogen (N) mineralization capacity. A field study was established in 1979 to understand the impact of long-term manure and/or chemical fertilizer application on soil fertility in a continuous maize cropping system. Soil samples were collected from field plots in 2012 from 9 fertilization treatments (M0CK, M0N, M0NPK, M30CK, M30N, M30NPK, M60CK, M60N, and M60NPK) where M0, M30, and M60 refer to manure applied at rates of 0, 30, and 60 t ha−1 yr−1, respectively; CK indicates no fertilizer; N and NPK refer to chemical fertilizer in the forms of either N or N plus phosphorus (P) and potassium (K). Soils were separated into three particle-size fractions (2000–250, 250–53, and <53 μm) by dry- and wet-sieving. A laboratory incubation study of these separated particle-size fractions was used to evaluate the effect of long-term manure, in combination with/without chemical fertilization application, on the accumulation and mineralization of SOC and total N in each fraction. Results showed that long-term manure application significantly increased SOC and total N content and enhanced C and N mineralization in the three particle-size fractions. The content of SOC and total N followed the order 2000–250 μm > 250–53μm > 53 μm fraction, whereas the amount of C and N mineralization followed the reverse order. In the <53 μm fraction, the M60NPK treatment significantly increased the amount of C and N mineralized (7.0 and 10.1 times, respectively) compared to the M0CK treatment. Long-term manure application, especially when combined with chemical fertilizers, resulted in increased soil microbial biomass C and N, and a decreased microbial metabolic quotient. Consequently, long-term manure fertilization was beneficial to both soil C and N turnover and microbial activity, and had significant effect on the microbial metabolic quotient

  3. Carbon and Nitrogen Mineralization in Relation to Soil Particle-Size Fractions after 32 Years of Chemical and Manure Application in a Continuous Maize Cropping System.

    PubMed

    Cai, Andong; Xu, Hu; Shao, Xingfang; Zhu, Ping; Zhang, Wenju; Xu, Minggang; Murphy, Daniel V

    2016-01-01

    Long-term manure application is recognized as an efficient management practice to enhance soil organic carbon (SOC) accumulation and nitrogen (N) mineralization capacity. A field study was established in 1979 to understand the impact of long-term manure and/or chemical fertilizer application on soil fertility in a continuous maize cropping system. Soil samples were collected from field plots in 2012 from 9 fertilization treatments (M0CK, M0N, M0NPK, M30CK, M30N, M30NPK, M60CK, M60N, and M60NPK) where M0, M30, and M60 refer to manure applied at rates of 0, 30, and 60 t ha(-1) yr(-1), respectively; CK indicates no fertilizer; N and NPK refer to chemical fertilizer in the forms of either N or N plus phosphorus (P) and potassium (K). Soils were separated into three particle-size fractions (2000-250, 250-53, and <53 μm) by dry- and wet-sieving. A laboratory incubation study of these separated particle-size fractions was used to evaluate the effect of long-term manure, in combination with/without chemical fertilization application, on the accumulation and mineralization of SOC and total N in each fraction. Results showed that long-term manure application significantly increased SOC and total N content and enhanced C and N mineralization in the three particle-size fractions. The content of SOC and total N followed the order 2000-250 μm > 250-53 μm > 53 μm fraction, whereas the amount of C and N mineralization followed the reverse order. In the <53 μm fraction, the M60NPK treatment significantly increased the amount of C and N mineralized (7.0 and 10.1 times, respectively) compared to the M0CK treatment. Long-term manure application, especially when combined with chemical fertilizers, resulted in increased soil microbial biomass C and N, and a decreased microbial metabolic quotient. Consequently, long-term manure fertilization was beneficial to both soil C and N turnover and microbial activity, and had significant effect on the microbial metabolic quotient. PMID

  4. Carbon and Nitrogen Mineralization in Relation to Soil Particle-Size Fractions after 32 Years of Chemical and Manure Application in a Continuous Maize Cropping System.

    PubMed

    Cai, Andong; Xu, Hu; Shao, Xingfang; Zhu, Ping; Zhang, Wenju; Xu, Minggang; Murphy, Daniel V

    2016-01-01

    Long-term manure application is recognized as an efficient management practice to enhance soil organic carbon (SOC) accumulation and nitrogen (N) mineralization capacity. A field study was established in 1979 to understand the impact of long-term manure and/or chemical fertilizer application on soil fertility in a continuous maize cropping system. Soil samples were collected from field plots in 2012 from 9 fertilization treatments (M0CK, M0N, M0NPK, M30CK, M30N, M30NPK, M60CK, M60N, and M60NPK) where M0, M30, and M60 refer to manure applied at rates of 0, 30, and 60 t ha(-1) yr(-1), respectively; CK indicates no fertilizer; N and NPK refer to chemical fertilizer in the forms of either N or N plus phosphorus (P) and potassium (K). Soils were separated into three particle-size fractions (2000-250, 250-53, and <53 μm) by dry- and wet-sieving. A laboratory incubation study of these separated particle-size fractions was used to evaluate the effect of long-term manure, in combination with/without chemical fertilization application, on the accumulation and mineralization of SOC and total N in each fraction. Results showed that long-term manure application significantly increased SOC and total N content and enhanced C and N mineralization in the three particle-size fractions. The content of SOC and total N followed the order 2000-250 μm > 250-53 μm > 53 μm fraction, whereas the amount of C and N mineralization followed the reverse order. In the <53 μm fraction, the M60NPK treatment significantly increased the amount of C and N mineralized (7.0 and 10.1 times, respectively) compared to the M0CK treatment. Long-term manure application, especially when combined with chemical fertilizers, resulted in increased soil microbial biomass C and N, and a decreased microbial metabolic quotient. Consequently, long-term manure fertilization was beneficial to both soil C and N turnover and microbial activity, and had significant effect on the microbial metabolic quotient.

  5. TORUS: Theory of Reactions for Unstable iSotopes Annual Continuation and Progress Report Year-2: March 1, 2011 - February 29, 2012

    SciTech Connect

    Arbanas, G; Elster, C; Escher, J; Mukhamedzanov, A; Nunes, F; Thompson, I J

    2012-02-24

    The TORUS collaboration derives its name from the research it focuses on, namely the Theory of Reactions for Unstable iSotopes. It is a Topical Collaboration in Nuclear Theory, and funded by the Nuclear Theory Division of the Office of Nuclear Physics in the Office of Science of the Department of Energy. The funding supports one postdoctoral researcher for the years 1 through 3. The collaboration brings together as Principal Investigators a large fraction of the nuclear reaction theorists currently active within the USA. The mission of the TORUS Topical Collaboration is to develop new methods that will advance nuclear reaction theory for unstable isotopes by using three-body techniques to improve direct-reaction calculations, and, by using a new partial-fusion theory, to integrate descriptions of direct and compound-nucleus reactions. This multi-institution collaborative effort is directly relevant to three areas of interest: the properties of nuclei far from stability; microscopic studies of nuclear input parameters for astrophysics, and microscopic nuclear reaction theory.

  6. Continuing high prevalence of VanA-type vancomycin-resistant enterococci on Norwegian poultry farms three years after avoparcin was banned.

    PubMed

    Borgen, K; Simonsen, G S; Sundsfjord, A; Wasteson, Y; Olsvik, O; Kruse, H

    2000-09-01

    Avoparcin was used as a feed additive in Norwegian broiler and turkey production from 1986 until 1995. It was banned due to the selection of VanA-type vancomycin-resistant enterococci (VRE) in animal husbandry and to reduce the potential for human exposure to VRE. The aim of the present study was to investigate the prevalence of VRE carriage in Norwegian poultry farmers and their poultry three years after avoparcin was banned. Corresponding faecal samples from poultry and humans on farms where avoparcin had previously been used (exposed farms, n = 73) and farms where avoparcin had never been used (unexposed farms, n = 74) were analysed for the presence of VRE. For each farm, one sample from the poultry house and one sample from the farmer were obtained. VRE were isolated from 72 of 73 (99%) and eight of 74 (11%) poultry samples from exposed and unexposed farms, respectively. VRE were isolated from 13 of 73 (18%) and one of 74 (1%) farmer samples from exposed and unexposed farms, respectively. All VRE isolates were highly resistant to vancomycin and possessed the vanA gene, as shown by PCR. The high prevalence of VRE is in accordance with previous Norwegian studies, and shows a remarkable stability of the VanA resistance determinant in an apparently non-selective environment. PMID:11021580

  7. Protective factors and predictors of vulnerability to chronic stress: a comparative study of 4 communities after 7 years of continuous rocket fire.

    PubMed

    Gelkopf, Marc; Berger, Rony; Bleich, Avraham; Silver, Roxane Cohen

    2012-03-01

    Many communities across the world are chronically exposed to extreme violence. Responses of residents from a city and rural community in Southern Israel, both exposed to 7 years of daily mortar fire, were compared to residents from demographically, socio-economically and geographically comparable non-exposed control samples to examine protective factors and predictors of vulnerability to chronic war-related attacks. Samples from a highly exposed city (Sderot) and a highly exposed rural community region (Otef Aza), along with a demographically comparable comparison non-exposed city (Ofakim) and non-exposed rural community region (Hevel Lachish), were obtained in 2007 using Random Digit Dialing. In total, 740 individuals (81.8% participation rate) were interviewed about trauma exposure, mental health, functioning and health care utilization. In the highly exposed city of Sderot, 97.8% of residents had been in close proximity to falling rockets; in the highly exposed rural community region of Otef Aza, 95.5% were similarly exposed. Despite exposure to chronic rocket attacks, residents of Otef Aza evidenced little symptomatology: only one person (1.5%) reported symptoms consistent with probable posttraumatic stress disorder (PTSD) and functioning levels did not differ from those of non-exposed communities. In contrast, posttraumatic stress (PTS), distress, functional impairment and health care utilization were substantially higher in the highly exposed city of Sderot than the other three communities. Lack of resources was associated with increased vulnerability among city residents; predictors of PTS across all samples included being female, older, directly exposed to rockets, history of trauma, suffering economic loss, and lacking social support. Increased community solidarity, sense of belonging and confidence in authorities may have served a protective function for residents of rural communities, despite the chronic attacks to which they were exposed. PMID:22316441

  8. Geodetic Tying of Antarctica and India With 10 Years of Continuous GPS Measurements for Geodynamical and Strain Accumulation Studies in the South of Indian Peninsula

    NASA Astrophysics Data System (ADS)

    Ec, M.; N, R.

    2008-12-01

    To holistically understand the geodynamical and crustal deformation processes between India and Antarctica, two global networks (IND and ANT) have been chosen. The objective is to geodetically connect the two continents. The IGS Station at Diego Garcia (DGAR) is the common station between the two networks. 10 years of data from 1997 to 2007 were used. By these global networks' analyses, the stations HYDE in India and MAIT at Antarctica are geodetically tied through the station DGAR. Very long baselines have been estimated from HYDE and also from Kerguelen (KERG) to other chosen IGS stations in and around India and Antarctica. Our analysis and results using ANT network show an increase in the baseline lengths between Kerguelen in Antarctic plate and other stations such as SEY1, DGAR and COCO and shortening of baseline lengths between HYDE in Indian plate and all these above stations using IND network. The analysis using ANT network also shows lengthening of baselines from Kerguelen to the sites Yaragadee (YAR1) and Tidbinbilla (TID2) in Australian plate; and Seychelles (SEY1) in Male plate, COCO in the diffuse plate boundary between India and Australia and DGAR in Capricorn plate at the rates of 5.3cm/yr, 3.8cm/yr, 5.6mm/yr, 3.03 cm/yr and 5.5 cm/yr respectively. The high rate of movement of COCO Island in comparison to Seychelles could be the result of excessive strain accumulation due to the Indo-Australia diffuse plate boundary forces acting upon this region. The estimated elastic strain accumulation shows an increasing trend of 1.27x 10-8 yr-1 in the south of Indian peninsula. Our results show the precision of approximately 3-4mm (North), 5-6 mm (East), and 10-12mm (vertical) for the estimation of site coordinates. These results provide new information on the direction and rate of Indian plate motion, the driving mechanisms of Indian plate and intraplate seismicity of the Indian Ocean on the whole.

  9. Six years of high-precision quasi-continuous atmospheric greenhouse gas measurements at Trainou Tower (Orléans Forest, France)

    NASA Astrophysics Data System (ADS)

    Schmidt, M.; Lopez, M.; Yver Kwok, C.; Messager, C.; Ramonet, M.; Wastine, B.; Vuillemin, C.; Truong, F.; Gal, B.; Parmentier, E.; Cloué, O.; Ciais, P.

    2014-01-01

    Results from the Trainou tall tower measurement station installed in 2006, are presented for atmospheric measurements of CO2, CH4, N2O, SF6, CO, H2 mole fractions and Radon-222 activity. Air is sampled from four sampling heights (180 m, 100 m, 50 m and 5 m) of the Trainou 200 m television tower in the Orléans forest in France (47°57'53'' N, 2°06'45'' E, 131 m a.s.l.). The station is equipped with a custom-build CO2 analyzer (CARIBOU), which is based on a commercial NDIR analyser (Licor 6252), and a coupled gas chromatographic GC system equipped with ECD and FID (HP6890N, Agilent) and a reduction gas detector (PP1, Peak Performer). Air intakes, pumping and air drying system are shared between the CARIBOU and the GC systems. After some initial problems, we achieved short-term repeatability (1 sigma, over several days) for the GC system of of 0.05 ppm for CO2, 1.4 ppb for CH4, 0.25 ppb for N2O, 0.08 ppb for SF6, 0.88 ppb for CO and 3.8 for H2. The repeatability of the CARIBOU CO2 analyser is 0.06 ppm. In addition to the in-situ measurements, weekly flask sampling is performed, and flask air samples are analysed at the LSCE central laboratory for the same species as well for stable isotopes of CO2. The comparison between in-situ measurements and the flask sampling showed averaged differences of 0.08 ± 1.4 ppm CO2, 0.69 ± 7.3 ppb CH4, 0.64 ± 0.62 ppb N2O, 0.01 ± 0.1 ppt SF6 and 1.5 ± 5.3 ppb CO for the years 2008-2012. At Trainou station, the mean annual increase rates from 2007 to 2011 at the 180 m sampling height were 2.2 ppm yr-1 for CO2, 4 ppb yr-1 for CH4, 0.78 ppb yr-1 for N2O and 0.29 ppt yr-1 for SF6 respectively. For all species the 180 m sampling level showed the smallest diurnal variation. Mean diurnal gradients between the 50 m and the 180 m sampling level reached up to 30 ppm CO2, 15 ppm CH4 or 0.5 ppb N2O during night whereas the mean gradients are smaller than 0.5 ppm for CO2 and 1.5 ppb for CH4 during afternoon.

  10. Comparative Efficacy and Durability of Continuation Phase Cognitive Therapy for Preventing Recurrent Depression: Design of a Double-Blinded, Fluoxetine- and Pill-Placebo–Controlled, Randomized Trial with 2-Year Follow-up

    PubMed Central

    Thase, Michael E.

    2010-01-01

    Background Major depressive disorder (MDD) is highly prevalent and associated with disability and chronicity. Although cognitive therapy (CT) is an effective short-term treatment for MDD, a significant proportion of responders subsequently suffer relapses or recurrences. Purpose This design prospectively evaluates: 1) a method to discriminate CT-treated responders at lower versus higher risk for relapse; and 2) the subsequent durability of 8-month continuation phase therapies in randomized higher risk responders followed for an additional 24-months. The primary prediction is: after protocol treatments are stopped, higher risk patients randomly assigned to continuation phase CT (C-CT) will have a lower risk of relapse/recurrence than those randomized to fluoxetine (FLX). Methods Outpatients, aged 18 to 70 years, with recurrent MDD received 12–14 weeks of CT provided by 15 experienced therapists from two sites. Responders (i.e., no MDD and 17-item Hamilton Rating Scale for Depression ≤ 12) were stratified into higher and lower risk groups based on stability of remission during the last 6 weeks of CT. The lower risk group entered follow-up for 32 months; the higher risk group was randomized to 8 months of continuation phase therapy with either C-CT or clinical management plus either double-blinded FLX or pill placebo. Following the continuation phase, higher risk patients were followed by blinded evaluators for 24 months. Results The trial began in 2000. Enrollment is complete (N=523). The follow-up continues. Conclusions The trial evaluates the preventive effects and durability of acute and continuation phase treatments in the largest known sample of CT responders collected worldwide. PMID:20451668

  11. Development of the Learning Result of Innovation and Information Technology in Education Using CIPPA, for Third Year Students in the Bachelor of Education Program, Nakhon Phanom University

    ERIC Educational Resources Information Center

    Hanrin, Chanwit

    2014-01-01

    This research proposes (1) to develop the learning management plan for the Innovation and Information Technology in Education of the 3rd year students of the Bachelor of Education Program by using CIPPA effectively according to the criteria 75/75; (2) to study the effectiveness index of the learning management plan for the Innovation and…

  12. Sum up experience to make continuous progress.

    PubMed

    Liang, J

    1989-02-01

    Population control in China has been very successful in combatting the extremely rapid growth in population (birth rate: 1960's 33.65/1000; 1970's 24.57/1000; 1980's 18.3/1000). The female mean age for 1st marriage has increased from 19 in the 1950's to 22.63 in the 1980's. Infant mortality has declined substantially from the 1950's to the present (200 deaths/1000 vs. 81.3/1000 (cities)). Most people have embraced family planning and population control and have emphasized quality of childrearing vs. quantity. The goals of China's policy are as follows: economic development of the nation and well-being of individuals; coordination of population growth and socioeconomic development; implementation not only in accordance with state condition, but also according to the wishes of the people; continued success of the population and family planning organization network; integration of state guidance with individual voluntariness; and strengthening the unified leadership of the state. China's 3rd baby boom began in 1986 and will last through 1995. Unplanned children will count as 30% of the annual births. Government action is attempting to strengthen family planning education and research. These measures will help control the expected population boom.

  13. Continual improvement plan

    NASA Technical Reports Server (NTRS)

    1994-01-01

    NASA's approach to continual improvement (CI) is a systems-oriented, agency-wide approach that builds on the past accomplishments of NASA Headquarters and its field installations and helps achieve NASA's vision, mission, and values. The NASA of the future will fully use the principles of continual improvement in every aspect of its operations. This NASA CI plan defines a systematic approach and a model for continual improvement throughout NASA, stressing systems integration and optimization. It demonstrates NASA's constancy of purpose for improvement - a consistent vision of NASA as a worldwide leader in top-quality science, technology, and management practices. The CI plan provides the rationale, structures, methods, and steps, and it defines NASA's short term (1-year) objectives for improvement. The CI plan presents the deployment strategies necessary for cascading the goals and objectives throughout the agency. It also provides guidance on implementing continual improvement with participation from top leadership and all levels of employees.

  14. Learning Centres Development. UNESCO Regional Workshop on Learning Centre Development, and NFUAJ Workshop for the Promotion and Development of the UNESCO Co-Action World Terakoya Movement (3rd, Colombo, Sri Lanka, November 3-11, 1994). Draft Final Report.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific and Cultural Organization, Bangkok (Thailand). Principal Regional Office for Asia and the Pacific.

    This publication contains materials from a workshop organized to help its participants understand and apply the concept of learning centers. Chapter 1 is an introduction. Chapter 2 consists of two presentations: "Literacy and Continuing Education for Improvement of Quality of Life in Asia and the Pacific" and an explanation of the World Terakoya…

  15. An Analysis of the Relationship between 3rd Grade Teachers' Emotional Intelligence and Classroom Management Styles and Implications on Student Achievement in Title I Elementary Schools: A Correlational Study

    ERIC Educational Resources Information Center

    Dickey, Kershena A.

    2012-01-01

    Over the past twenty years extensive research has been conducted on emotional intelligence and its correlation to effective leadership. The initial studies were in large part related to the business sector. However, in recent years, more emphasis has been placed on its impact in the field of education. Emotional intelligence is the ability to…

  16. Nadir Testosterone Within First Year of Androgen-Deprivation Therapy (ADT) Predicts for Time to Castration-Resistant Progression: A Secondary Analysis of the PR-7 Trial of Intermittent Versus Continuous ADT

    PubMed Central

    Klotz, Laurence; O'Callaghan, Chris; Ding, Keyue; Toren, Paul; Dearnaley, David; Higano, Celestia S.; Horwitz, Eric; Malone, Shawn; Goldenberg, Larry; Gospodarowicz, Mary; Crook, Juanita M.

    2015-01-01

    Purpose Three small retrospective studies have suggested that patients undergoing continuous androgen deprivation (CAD) have superior survival and time to progression if lower castrate levels of testosterone (< 0.7 nmol/L) are achieved. Evidence from prospective large studies has been lacking. Patients and Methods The PR-7 study randomly assigned patients experiencing biochemical failure after radiation therapy or surgery plus radiation therapy to CAD or intermittent androgen deprivation. The relationship between testosterone levels in the first year and cause-specific survival (CSS) and time to androgen-independent progression in men in the CAD arm was evaluated using Cox regression. Results There was a significant difference in CSS (P = .015) and time to hormone resistance (P = .02) among those who had first-year minimum nadir testosterone ≤ 0.7, > 0.7 to ≤ 1.7, and ≥ 1.7 nmol/L. Patients with first-year nadir testosterone consistently > 0.7 nmol/L had significantly higher risks of dying as a result of disease (0.7 to 1.7 nmol/L: hazard ratio [HR], 2.08; 95% CI, 1.28 to 3.38; > 1.7 nmol/L: HR, 2.93; 95% CI, 0.70 to 12.30) and developing hormone resistance (0.7 to 1.7 nmol/L: HR, 1.62; 95% CI, 1.20 to 2.18; ≥ 1.7 nmol/L: HR, 1.90; 95% CI, 0.77 to 4.70). Maximum testosterone ≥ 1.7 nmol/L predicted for a higher risk of dying as a result of disease (P = .02). Conclusion Low nadir serum testosterone (ie, < 0.7 mmol/L) within the first year of androgen-deprivation therapy correlates with improved CSS and duration of response to androgen deprivation in men being treated for biochemical failure undergoing CAD. PMID:25732157

  17. A Randomized Clinical Trial to Assess the Efficacy and Safety of Real-Time Continuous Glucose Monitoring in the Management of Type 1 Diabetes in Young Children Aged 4 to <10 Years

    PubMed Central

    Mauras, Nelly; Beck, Roy; Xing, Dongyuan; Ruedy, Katrina; Buckingham, Bruce; Tansey, Michael; White, Neil H.; Weinzimer, Stuart A.; Tamborlane, William; Kollman, Craig

    2012-01-01

    OBJECTIVE Continuous glucose monitoring (CGM) has been demonstrated to improve glycemic control in adults with type 1 diabetes but less so in children. We designed a study to assess CGM benefit in young children aged 4 to 9 years with type 1 diabetes. RESEARCH DESIGN AND METHODS After a run-in phase, 146 children with type 1 diabetes (mean age 7.5 ± 1.7 years, 64% on pumps, median diabetes duration 3.5 years) were randomly assigned to CGM or to usual care. The primary outcome was reduction in HbA1c at 26 weeks by ≥0.5% without the occurrence of severe hypoglycemia. RESULTS The primary outcome was achieved by 19% in the CGM group and 28% in the control group (P = 0.17). Mean change in HbA1c was −0.1% in each group (P = 0.79). Severe hypoglycemia rates were similarly low in both groups. CGM wear decreased over time, with only 41% averaging at least 6 days/week at 26 weeks. There was no correlation between CGM use and change in HbA1c (rs = −0.09, P = 0.44). CGM wear was well tolerated, and parental satisfaction with CGM was high. However, parental fear of hypoglycemia was not reduced. CONCLUSIONS CGM in 4- to 9-year-olds did not improve glycemic control despite a high degree of parental satisfaction with CGM. We postulate that this finding may be related in part to limited use of the CGM glucose data in day-to-day management and to an unremitting fear of hypoglycemia. Overcoming the barriers that prevent integration of these critical glucose data into day-to-day management remains a challenge. PMID:22210571

  18. One year of Puma Painting: site experiences

    NASA Astrophysics Data System (ADS)

    Stein, Matthew R.

    1999-11-01

    The PumaPaint project is a web robot that allows users to create original artwork on the World Wide Web. The site allows control of a PUMA 760 robot equipped with four paintbrushes; jars of red, green, blue and yellow paint and white paper attached to an easel. Users must download a JavaTM interface allowing interactive control of the robot. This interface contains two windows showing live camera views of the work site and various controls for connecting and disconnecting to the robot, viewing the task status and controlling the painting task. During the first year of operation of the site, June 3rd, 1998 to June 2nd 1999, approximately 5,000 users produced 390 canvases. This paper presents summary data from one year of operation, discusses the author's experiences in operating the site and examines some of the artwork produced.

  19. Interactive Session: U.S. & Developing Countries. A 2-Way Street. Report of an Interactive Session held at the National Conference of Librarians and International Development (3rd, Corvallis, Oregon, April 28-30, 1991).

    ERIC Educational Resources Information Center

    1991

    This working outline provides a detailed plan and background information for conference participants, who were assigned to assist the government and an institution in one of four developing countries in planning for the establishment and/or strengthening of a system's information capabilities over a 10-year period. These projects were: (1) the…

  20. Strengthening the influenza vaccine virus selection and development process: Report of the 3rd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at WHO headquarters, Geneva, Switzerland, 1-3 April 2014.

    PubMed

    Ampofo, William K; Azziz-Baumgartner, Eduardo; Bashir, Uzma; Cox, Nancy J; Fasce, Rodrigo; Giovanni, Maria; Grohmann, Gary; Huang, Sue; Katz, Jackie; Mironenko, Alla; Mokhtari-Azad, Talat; Sasono, Pretty Multihartina; Rahman, Mahmudur; Sawanpanyalert, Pathom; Siqueira, Marilda; Waddell, Anthony L; Waiboci, Lillian; Wood, John; Zhang, Wenqing; Ziegler, Thedi

    2015-08-26

    Despite long-recognized challenges and constraints associated with their updating and manufacture, influenza vaccines remain at the heart of public health preparedness and response efforts against both seasonal and potentially pandemic influenza viruses. Globally coordinated virological and epidemiological surveillance is the foundation of the influenza vaccine virus selection and development process. Although national influenza surveillance and reporting capabilities are being strengthened and expanded, sustaining and building upon recent gains has become a major challenge. Strengthening the vaccine virus selection process additionally requires the continuation of initiatives to improve the timeliness and representativeness of influenza viruses shared by countries for detailed analysis by the WHO Global Influenza Surveillance and Response System (GISRS). Efforts are also continuing at the national, regional, and global levels to better understand the dynamics of influenza transmission in both temperate and tropical regions. Improved understanding of the degree of influenza seasonality in tropical countries of the world should allow for the strengthening of national vaccination policies and use of the most appropriate available vaccines. There remain a number of limitations and difficulties associated with the use of HAI assays for the antigenic characterization and selection of influenza vaccine viruses by WHOCCs. Current approaches to improving the situation include the more-optimal use of HAI and other assays; improved understanding of the data produced by neutralization assays; and increased standardization of serological testing methods. A number of new technologies and associated tools have the potential to revolutionize influenza surveillance and response activities. These include the increasingly routine use of whole genome next-generation sequencing and other high-throughput approaches. Such approaches could not only become key elements in outbreak

  1. Strengthening the influenza vaccine virus selection and development process: Report of the 3rd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at WHO headquarters, Geneva, Switzerland, 1-3 April 2014.

    PubMed

    Ampofo, William K; Azziz-Baumgartner, Eduardo; Bashir, Uzma; Cox, Nancy J; Fasce, Rodrigo; Giovanni, Maria; Grohmann, Gary; Huang, Sue; Katz, Jackie; Mironenko, Alla; Mokhtari-Azad, Talat; Sasono, Pretty Multihartina; Rahman, Mahmudur; Sawanpanyalert, Pathom; Siqueira, Marilda; Waddell, Anthony L; Waiboci, Lillian; Wood, John; Zhang, Wenqing; Ziegler, Thedi

    2015-08-26

    Despite long-recognized challenges and constraints associated with their updating and manufacture, influenza vaccines remain at the heart of public health preparedness and response efforts against both seasonal and potentially pandemic influenza viruses. Globally coordinated virological and epidemiological surveillance is the foundation of the influenza vaccine virus selection and development process. Although national influenza surveillance and reporting capabilities are being strengthened and expanded, sustaining and building upon recent gains has become a major challenge. Strengthening the vaccine virus selection process additionally requires the continuation of initiatives to improve the timeliness and representativeness of influenza viruses shared by countries for detailed analysis by the WHO Global Influenza Surveillance and Response System (GISRS). Efforts are also continuing at the national, regional, and global levels to better understand the dynamics of influenza transmission in both temperate and tropical regions. Improved understanding of the degree of influenza seasonality in tropical countries of the world should allow for the strengthening of national vaccination policies and use of the most appropriate available vaccines. There remain a number of limitations and difficulties associated with the use of HAI assays for the antigenic characterization and selection of influenza vaccine viruses by WHOCCs. Current approaches to improving the situation include the more-optimal use of HAI and other assays; improved understanding of the data produced by neutralization assays; and increased standardization of serological testing methods. A number of new technologies and associated tools have the potential to revolutionize influenza surveillance and response activities. These include the increasingly routine use of whole genome next-generation sequencing and other high-throughput approaches. Such approaches could not only become key elements in outbreak

  2. Effect of Cryoanalgesia Combined with Intravenous Continuous Analgesia in Thoracotomy Patients

    PubMed Central

    Gwak, Mi Sook; Hahm, Tae Soo; Cho, Hyun Sung; Cho, Chung Hwan; Song, Jae Gyok

    2004-01-01

    Fifty patients undergoing thoracotomy was studied to compare the effects of cryoanalgesia combined with intravenous continuous analgesia (IVCA). Patients were randomized into two groups: IVCA group and IVCA-cryo group. Subjective pain intensity was assessed on a visual analogue scale at rest (VAS-R) and during movement (VAS-M). Analgesic requirements were evaluated over the 7 days following surgery. Forced vital capacity (FVC) and forced expiratory volume in 1 sec (FEV1) were measured before operation, on the 2nd and 7th postoperative days (POD). We interviewed patients by telephone to evaluate the prevalence of post-thoracotomy pain at the 1st, 3rd, and 6th months postoperatively. No significant differences were observed between the two groups with respect to postoperative pain, analgesic requirements, side effects, respiratory complications, or prevalence of post-thoracotomy pain. However, a significant increase in FVC and FEV1 was observed on the 7th POD in IVCAc-ryo group. The incidence of the post-thoracotomy pain at the 1st, 3rd, and 6th months postoperatively was 68, 60, and 44% in IVCA group, and 88, 68, and 28% in IVCA-cryo group, respectively. Our study showed that cryoanalgesia combined with IVCA effectively restore respiratory function on 7th POD, but that it was not effective at reducing the incidence of post-thoracotomy pain. PMID:14966345

  3. Effect of cryoanalgesia combined with intravenous continuous analgesia in thoracotomy patients.

    PubMed

    Gwak, Mi Sook; Yang, Mikyung; Hahm, Tae Soo; Cho, Hyun Sung; Cho, Chung Hwan; Song, Jae Gyok

    2004-02-01

    Fifty patients undergoing thoracotomy was studied to compare the effects of cryoanalgesia combined with intravenous continuous analgesia (IVCA). Patients were randomized into two groups: IVCA group and IVCA-cryo group. Subjective pain intensity was assessed on a visual analogue scale at rest (VAS-R) and during movement (VAS-M). Analgesic requirements were evaluated over the 7 days following surgery. Forced vital capacity (FVC) and forced expiratory volume in 1 sec (FEV1) were measured before operation, on the 2nd and 7th postoperative days (POD). We interviewed patients by telephone to evaluate the prevalence of post-thoracotomy pain at the 1st, 3rd, and 6th months postoperatively. No significant differences were observed between the two groups with respect to postoperative pain, analgesic requirements, side effects, respiratory complications, or prevalence of post-thoracotomy pain. However, a significant increase in FVC and FEV1 was observed on the 7th POD in IVCAcryo group. The incidence of the post-thoracotomy pain at the 1st, 3rd, and 6th months postoperatively was 68, 60, and 44% in IVCA group, and 88, 68, and 28% in IVCAcryo group, respectively. Our study showed that cryoanalgesia combined with IVCA effectively restore respiratory function on 7th POD, but that it was not effective at reducing the incidence of post-thoracotomy pain. PMID:14966345

  4. [Neurological alterations and intellectual deficits with sudden visual loss in a 7-year-old boy].

    PubMed

    Gotz-Wieckowska, A; Pawlak, M; Siwiec-Proscinska, J; Seget, M

    2013-05-01

    Neuronal ceroid-lipofuscinoses (NLC) are a clinically and genetically heterogeneous group of lysosomal storage diseases. The most common NCL is the juvenile type which begins between the ages of 4 and 10 years in most cases with sudden visual loss which correlates with maculopathy and leads to blindness within a few years of presentation. After several years neurological deterioration ensues and in most cases death occurs in the 3rd decade of life. As with other storage disorders NCL is an incurable disease. PMID:23224126

  5. Results of a monitoring program of continuous water levels and physical water properties at the Operable Unit 1 area of the Savage Municipal Well Superfund site, Milford, New Hampshire, water years 2000-03

    USGS Publications Warehouse

    Harte, Philip T.

    2005-01-01

    The Milford-Souhegan glacial-drift (MSGD) aquifer, in south-central New Hampshire, is an important source of industrial, commercial, and domestic water. The MSGD aquifer was also an important source of drinking water for the town of Milford until it was found to contain high concentrations of volatile organic compounds (VOCs) in the Savage and Keyes municipal-supply wells in the early 1980s. A VOC plume was found to cover part of the southwestern half of the MSGD aquifer. In September 1984, the site was designated a Superfund site, called the Savage Municipal Well Superfund site. The primary source area of contaminants was a former tool manufacturing facility (called the OK Tool facility, and now called the Operable Unit 1 (OU1) area) that disposed of solvents at the surface and in the subsurface. The facility was closed in 1987 and removed in 1998. A low-permeability containment barrier wall was constructed and installed in the overburden (MSGD aquifer) in 1998 to encapsulate the highest concentrations of VOCs, and a pump-and-treat remediation facility was also added. Remedial operations of extraction and injection wells started in May 1999. A network of water-level monitoring sites was implemented in water year 2000 (October 1, 1999, through September 30, 2000) in the OU1 area to help assess the effectiveness of remedial operations to mitigate the VOC plume, and to evaluate the effect of the barrier wall and remedial operations on the hydraulic connections across the barrier and between the overburden and underlying bedrock. Remedial extraction and injections wells inside and outside the barrier help isolate ground-water flow inside the barrier and the further spreading of VOCs. This report summarizes both continuous and selected periodic manual measurements of water level and physical water properties (specific conductance and water temperature) for 10 monitoring locations during water years 2000-03. Additional periodic manual measurements of water levels were

  6. Clinical experience and results of treatment with suprofen in pediatrics. 3rd communication: Antipyretic effect and tolerability of repeat doses of suprofen and paracetamol syrup in hospitalized children/A single-blind study.

    PubMed

    Weippl, G; Michos, N; Sundal, E J; Stocker, H

    1985-01-01

    Antipyretic effect and tolerability of alpha-methyl-4-(2-thienylcarbonyl)-phenyl acetic acid (suprofen, Suprol), syrup and paracetamol (acetaminophen) were compared within the scope of the present randomized single-blind study; the test population included a total of 115 children ranging in age from 6 months to 12 years. All patients were admitted to the hospital with an average temperature of 39.3 degrees C, their disease being caused by bacterial or viral infections. The dose levels for treatment with syrup depended upon the children's age and body weight. Treatment was in most cases given for two days; a three-times-a-day schedule was used. The (rectal) temperature as well as pulse and respiratory rates were measured prior to treatment and 0.5, 1, 1.5, 2, 3, 4, 5, 6 h after first administration of the test preparations. The results showed that the antipyretic effect of suprofen was in both age groups at all rating times statistically significantly superior to that of paracetamol. Pulse and respiratory rates dropped in both age groups after treatment; the means were within the normal range at all rating times. Adverse drug reactions were seen in 5 patients on suprofen and in 3 cases on paracetamol. It is, however, questionable whether such reactions are drug-dependent. PMID:3911963

  7. [Clinical, biochemical and histopathological development of post-transfusional non-A, non-B hepatitis from the acute picture to chronicity during 13.3 years].

    PubMed

    de Andrade Júnior, D R; Câmara Lopes, L H; de Souza, F C; de Andrade, D R

    1989-01-01

    This case was of a 45 year old female patient with a post-transfusion non-A non-B hepatitis which was accompanied since an acute phase to hepatic cirrhosis during a period of 159.7 months or 13.3 years. Four hepatic biopsies were carried out and they divided the follow-up into 5 evolutive periods. The biopsies revealed a progressive histologic from chronic persistent hepatitis to an active chronic hepatitis and cirrhosis. The aminotransferases followed a floating course in the whole period, with ALT greater than AST starting from the 3rd period. The 3rd period (from 5th to 8th year) was of least activity of the aminotransferases, and the 4th and 5th periods (from 8th to 13th year) showed the highest activity of ALT. The 2nd period (from 3rd to 5th year) showed the least portion of gamma globulin and the highest of albumin in comparison with the others. There was no connection between the levels of aminotransferases and the values of gamma globulin and albumin in the follow up process. The treatment employed in the 5th evolutive period (prednisone and colchicine) did not present any biochemical improvement.

  8. Landsat Data Continuity Mission

    USGS Publications Warehouse

    ,

    2007-01-01

    The Landsat Data Continuity Mission (LDCM) is a partnership between the National Aeronautics and Space Administration (NASA) and the U.S. Geological Survey (USGS) to place the next Landsat satellite in orbit by late 2012. The Landsat era that began in 1972 will become a nearly 45-year global land record with the successful launch and operation of the LDCM. The LDCM will continue the acquisition, archival, and distribution of multispectral imagery affording global, synoptic, and repetitive coverage of the Earth's land surfaces at a scale where natural and human-induced changes can be detected, differentiated, characterized, and monitored over time. The mission objectives of the LDCM are to (1) collect and archive medium resolution (circa 30-m spatial resolution) multispectral image data affording seasonal coverage of the global landmasses for a period of no less than 5 years; (2) ensure that LDCM data are sufficiently consistent with data from the earlier Landsat missions, in terms of acquisition geometry, calibration, coverage characteristics, spectral characteristics, output product quality, and data availability to permit studies of land-cover and land-use change over time; and (3) distribute LDCM data products to the general public on a nondiscriminatory basis and at a price no greater than the incremental cost of fulfilling a user request. Distribution of LDCM data over the Internet at no cost to the user is currently planned.

  9. Landsat Data Continuity Mission

    USGS Publications Warehouse

    ,

    2012-01-01

    The Landsat Data Continuity Mission (LDCM) is a partnership formed between the National Aeronautics and Space Administration (NASA) and the U.S. Geological Survey (USGS) to place the next Landsat satellite in orbit in January 2013. The Landsat era that began in 1972 will become a nearly 41-year global land record with the successful launch and operation of the LDCM. The LDCM will continue the acquisition, archiving, and distribution of multispectral imagery affording global, synoptic, and repetitive coverage of the Earth's land surfaces at a scale where natural and human-induced changes can be detected, differentiated, characterized, and monitored over time. The mission objectives of the LDCM are to (1) collect and archive medium resolution (30-meter spatial resolution) multispectral image data affording seasonal coverage of the global landmasses for a period of no less than 5 years; (2) ensure that LDCM data are sufficiently consistent with data from the earlier Landsat missions in terms of acquisition geometry, calibration, coverage characteristics, spectral characteristics, output product quality, and data availability to permit studies of landcover and land-use change over time; and (3) distribute LDCM data products to the general public on a nondiscriminatory basis at no cost to the user.

  10. Almost twenty years' search of transuranium isotopes in effluents discharged to air from nuclear power plants with VVER reactors.

    PubMed

    Hölgye, Z; Filgas, R

    2006-04-01

    Airborne effluents of 5 stacks (stacks 1-5) of three nuclear power plants, with 9 pressurized water reactors VVER of 4,520 MWe total power, were searched for transuranium isotopes in different time periods. The search started in 1985. The subject of this work is a presentation of discharge data for the period of 1998-2003 and a final evaluation. It was found that 238Pu, 239,240Pu, 241Am, 242Cm, and 244Cm can be present in airborne effluents. Transuranium isotope contents in most of the quarterly effluent samples from stacks 2, 4 and 5 were not measurable. Transuranium isotopes were present in the effluents from stack l during all 9 years of the study and from stack 3 since the 3rd quarter of 1996 as a result of a defect in the fuel cladding. A relatively high increase of transuranium isotopes in effluents from stack 3 occurred in the 3rd quarter of 1999, and a smaller increase occurred in the 3rd quarter of 2003. In each instance 242Cm prevailed in the transuranium isotope mixtures. 238Pu/239,240Pu, 241Am/239,240Pu, 242Cm/239,240Pu, and 244Cm/239,240Pu ratios in fuel for different burn-up were calculated, and comparison of these ratios in fuel and effluents was performed.

  11. Elements of Effective Practice for Mentoring [TM]. 3rd Edition

    ERIC Educational Resources Information Center

    MENTOR, 2009

    2009-01-01

    As a strategy for helping young people succeed in school, work and life, mentoring works. It helps give young people the confidence, resources and support they need to achieve their potential. The fact is this: these positive outcomes are only possible when young people are engaged in high-quality mentoring relationships. The "Elements of…

  12. 3rd Miami international conference on alternative energy sources

    SciTech Connect

    Nejat Veziroglu, T.

    1980-01-01

    The conference includes sessions on solar energy, ocean thermal energy, wind energy, hydro power, nuclear breeders and nuclear fusion, synthetic fuels from coal or wastes, hydrogen production and uses, formulation of workable policies on energy use and energy conservation, heat and energy storage, and energy education. The volume of the proceedings presents the papers and lectures in condensed format grouped by subject under forty-two sessions for 319 presentations.

  13. Curriculum Based Assessment: A Primer. 3rd Edition

    ERIC Educational Resources Information Center

    Hargis, Charles H.

    2004-01-01

    The use of curriculum based assessment (CBA) to ensure learning disabled and low achieving students adequate educational opportunity remains the focus in this direct and comprehensive third edition. The additions to this edition are in the way of providing detail and explanation in the context of current and emerging issues in educational…

  14. Microstructure Modeling of 3rd Generation Disk Alloy

    NASA Technical Reports Server (NTRS)

    Jou, Herng-Jeng

    2008-01-01

    The objective of this initiative, funded by NASA's Aviation Safety Program, is to model, validate, and predict, with high fidelity, the microstructural evolution of third-generation high-refractory Ni-based disc superalloys during heat treating and service conditions. This initiative is a natural extension of the DARPA-AIM (Accelerated Insertion of Materials) initiative with GE/Pratt-Whitney and with other process simulation tools. Strong collaboration with the NASA Glenn Research Center (GRC) is a key component of this initiative and the focus of this program is on industrially relevant disk alloys and heat treatment processes identified by GRC. Employing QuesTek s Computational Materials Dynamics technology and PrecipiCalc precipitation simulator, physics-based models are being used to achieve high predictive accuracy and precision. Combining these models with experimental data and probabilistic analysis, "virtual alloy design" can be performed. The predicted microstructures can be optimized to promote desirable features and concurrently eliminate nondesirable phases that can limit the reliability and durability of the alloys. The well-calibrated and well-integrated software tools that are being applied under the proposed program will help gas turbine disk alloy manufacturers, processing facilities, and NASA, to efficiently and effectively improve the performance of current and future disk materials.

  15. Pet Care Teaching Unit: 1st-3rd Grades.

    ERIC Educational Resources Information Center

    Peninsula Humane Society, San Mateo, CA.

    Activities in this unit are designed to familiarize primary grade students with the responsibilities involved in pet ownership. Teaching plans are provided for a total of 12 lessons involving social studies, language arts, math, and health sciences. Activities adaptable for readers and non-readers focus on pet overpopulation, care of pets when…

  16. Airfield construction (3rd revised and enlarged edition)

    NASA Astrophysics Data System (ADS)

    Goretskii, Leonid I.; Boguslavskii, Adol'f. M.; Serebrenikov, Vadim A.; Barzdo, V. I.; Leshchitskaia, T. P.; Polosin-Nikitin, S. M.

    The principal engineering aspects of airfield construction are discussed. In particular, attention is given to the fundamental principles and organizational aspects of airfield construction; excavation work and airfield layout; construction of drainage systems; foundations and pavements; and quality control and safety engineering. The discussion also covers the operation of various support plants, including concrete production and mixing, production of asphalt-concrete mixtures and organic binders, production of structural steel and reinforced concrete components, and operation of stone quarries and gravel pits.

  17. Proceedings of the 3rd Annual SCOLE Workshop

    NASA Technical Reports Server (NTRS)

    Taylor, Lawrence W., Jr. (Compiler)

    1987-01-01

    Topics addressed include: modeling and controlling the Spacecraft Control Laboratory Experiment (SCOLE) configurations; slewing maneuvers; mathematical models; vibration damping; gravitational effects; structural dynamics; finite element method; distributed parameter system; on-line pulse control; stability augmentation; and stochastic processes.

  18. Rentz's Student Affairs Practice in Higher Education. 3rd Edition

    ERIC Educational Resources Information Center

    MacKinnon, Fiona J. D.

    2004-01-01

    Students in the field, as well as experienced practitioners and administrators, will herein find an up-to-date and in-depth study of the major student affairs functions of a comprehensive campus program. Within its covers, the graduate student will find chapters describing everything the person new to student affairs needs to know about the major…

  19. Smith Newton Vehicle Performance Evaluation - 3rd Quarter 2012 (Brochure)

    SciTech Connect

    Not Available

    2013-03-01

    The Fleet Test and Evaluation Team at the U.S. Department of Energy's National Renewable Energy Laboratory is evaluating and documenting the performance of electric and plug-in hybrid electric drive systems in medium-duty trucks across the nation. Through this project, Smith Electric Vehicles will build and deploy 500 all-electric medium-duty trucks. The trucks will be deployed in diverse climates across the country.

  20. The radiology of joint disease. 3rd Ed

    SciTech Connect

    Forrester, D.M.; Brown, J.C.

    1987-01-01

    The book is a systematic radiographic approach to the arthritides. Part one deals with hand abnormalities ''to facilitate the teaching of basic principles and to dramatize the differences between radiographic features of various arthritides,'' as stated in the forward of the first edition. Part two, ''Arthritis from Head to Foot,'' illustrates the same diseases as they affect other joints. The ABCs (alignment, bone mineralization, cartilage space, soft tissue) approach is followed throughout the book. For example, reflex sympathetic dystrophy syndrome is dealt with in six different locations, and metatarsal stress fractures are mentioned in a chapter on erosions in rheumatoid arthritis.

  1. Business planning for scientists and engineers [3rd edition

    SciTech Connect

    Servo, Jenny C.

    1999-09-01

    This combination text/workbook is intended for use by scientists or engineers actively engaged in developing a product or technology to commercial production. The 'how' of planning is a central theme with special emphasis on development of operational plans and strategic thinking.

  2. Essentials of nuclear medicine imaging. 3rd edition

    SciTech Connect

    Mettler, F.A.; Guiberteau, M.J.

    1991-01-01

    This book covers topics ranging from basic physics and instrumentation to various aspects of clinical imaging and regulatory issues. It includes a section on single photon emission computed tomography (SPECT). The clinical sections include newer aspects of nuclear medicine, such as antibody imaging, pharmacologic stress, bone mineral analysis, evaluation of renovascular hypertension, and the role of gallium in patients with acquired immunodeficiency syndrome.

  3. Developmental Surface and Phonological Dysgraphia in German 3rd Graders

    ERIC Educational Resources Information Center

    Cholewa, Jurgen; Mantey, Stefanie; Heber, Stefanie; Hollweg, Wibke

    2010-01-01

    The investigation of developmental reading and spelling disorders within the framework provided by cognitive neuropsychology has yielded interesting results for several alphabetic orthographies, for example English, Italian, and French. However, this approach has not attracted much attention in German speaking countries up to now. The following…

  4. Prediction of Grade of Dropout from 3rd Grade Data.

    ERIC Educational Resources Information Center

    Lloyd, Dee Norman; Bleach, Gail

    Measures of background characteristics, school performance, and test achievement were analyzed for four race-by-sex samples of third graders who were known to have later become high school dropouts. In each sample, age in the third grade, course marks, and standardized achievement scores were found to be significantly related to the grade in which…

  5. Structures for the 3rd Generation Reusable Concept Vehicle

    NASA Technical Reports Server (NTRS)

    Hrinda, Glenn A.

    2001-01-01

    A major goal of NASA is to create an advance space transportation system that provides a safe, affordable highway through the air and into space. The long-term plans are to reduce the risk of crew loss to 1 in 1,000,000 missions and reduce the cost of Low-Earth Orbit by a factor of 100 from today's costs. A third generation reusable concept vehicle (RCV) was developed to assess technologies required to meet NASA's space access goals. The vehicle will launch from Cape Kennedy carrying a 25,000 lb. payload to the International Space Station (ISS). The system is an air breathing launch vehicle (ABLV) hypersonic lifting body with rockets and uses triple point hydrogen and liquid oxygen propellant. The focus of this paper is on the structural concepts and analysis methods used in developing the third generation reusable launch vehicle (RLV). Member sizes, concepts and material selections will be discussed as well as analysis methods used in optimizing the structure. Analysis based on the HyperSizer structural sizing software will be discussed. Design trades required to optimize structural weight will be presented.

  6. The Art of Problem Posing. 3rd Edition

    ERIC Educational Resources Information Center

    Brown, Stephen I.; Walter, Marion I.

    2005-01-01

    The new edition of this classic book describes and provides a myriad of examples of the relationships between problem posing and problem solving, and explores the educational potential of integrating these two activities in classrooms at all levels. "The Art of Problem Posing, Third Edition" encourages readers to shift their thinking about problem…

  7. International directory of electric utilities, 3rd Edition

    SciTech Connect

    Not Available

    1991-01-01

    The book covers 162 countries in Europe, Asia, Africa, Middle East, and Latin America. It contains hundreds of names of key utility executives, utility addresses, plus telephone, fax, and telex numbers. Power plant construction plants, new T D facilities and lines, names of major plants plus their locations, capacity, fuels, type of generation, etc. are included. It also includes listing of international engineering consultants and key executives, translations of key technical terms, and maps showing key facilities for all countries.

  8. Reconceptualizing Instructional Supervision for 3rd Millennium School Systems.

    ERIC Educational Resources Information Center

    Duffy, Francis M.

    2000-01-01

    Using the literature and experiences of theorists and practitioners from several interrelated areas (knowledge work, organization learning/development, sociotechnical systems design, and quality improvement), this article proposes a new instructional supervision paradigm called Knowledge Work Supervision aimed at improving school systems'…

  9. Advanced Materials Research with 3RD Generation Synchrotron Light

    NASA Astrophysics Data System (ADS)

    Soukiassian, P.; D'angelo, M.; Enriquez, H.; Aristov, V. Yu.

    H and D surface nanochemistry on an advanced wide band gap semiconductor, silicon carbide is investigated by synchrotron radiation-based core level and valence band photoemission, infrared absorption and scanning tunneling spectroscopy, showing the 1st example of H/D-induced semiconductor surface metallization, that also occurs on a pre-oxidized surface. These results are compared to recent state-of-the-art ab-initio total energy calculations. Most interestingly, an amazing isotopic behavior is observed with a smaller charge transfer from D atoms suggesting the role of dynamical effects. Such findings are especially exciting in semiconductor physics and in interface with biology.

  10. Studies on Metadiscourse Since the 3rd Millennium

    ERIC Educational Resources Information Center

    Wei, Jing; Li, Yan; Zhou, Ting; Gong, Zhiwei

    2016-01-01

    Metadiscourse refer to linguistic resources that are used to refer to the act and the context of writing about some subject matter. Study of metadiscourse provides a gateway for understanding interactional features of texts or speech, looking beyond the ideational dimension of texts at how writers characterize the world and function…

  11. 3rd International Conference on Turbulent Mixing and Beyond

    NASA Astrophysics Data System (ADS)

    Abarzhi, Snezhana I.; Gauthier, Serge; Keane, Christopher J.; Niemela, Joseph J.

    2013-07-01

    1. Introduction 'Turbulent Mixing and Beyond' (TMB) is the programme established for scientists, by scientists. It is merit-based, and is shaped by requirements of academic credentials, and novelty and quality of information. The goals of this programme are to expose the generic problem of non-equilibrium turbulent processes to a wide scientific community, to promote the development of new ideas in tackling the fundamental aspects of the problem, to assist in application of novel approaches in a broad range of phenomena, in which the turbulent processes occur, and to have a potential impact on technology. The programme was founded in 2007 with the support of the international scientific community and of the US National Science Foundation, the US Air Force Office of the Scientific Research and its European Office for Research and Development in the UK, the UNESCO-IAEA International Centre for Theoretical Physics in Italy, the Commissariat l'Energie Atomique in France, the US Department of Energy and the Department of Energy National Laboratories, the Institute for Laser Engineering in Japan, and the University of Chicago in the USA. The International Conference on Turbulent Mixing and Beyond provides opportunities to bring together researchers from the areas, which include but are not limited to, fluid dynamics, plasmas, high energy density physics, astrophysics, material science, combustion, atmospheric and earth sciences, nonlinear and statistical physics, applied mathematics, probability and statistics, data processing and computations, optics and communications, and to have their attention focused on the long-standing formidable task of non-equilibrium turbulent processes. 2. Non-equilibrium turbulent processes Non-equilibrium turbulent processes play a key role in a wide variety of phenomena, ranging from astrophysical to atomistic scales, under either high or low energy density conditions. Inertial confinement and magnetic fusion, light-matter interaction and non-equilibrium heat transfer, strong shocks and explosions, material transformation under high strain rate, supernovae and accretion discs, stellar non-Boussinesq and magneto-convection, planetary interiors and mantle-lithosphere tectonics, premixed and non-premixed combustion, non-canonical wall-bounded flows, hypersonic and supersonic boundary layers, dynamics of atmosphere and oceanography, are just a few examples to list. A grip on non-equilibrium turbulent processes is crucial for cutting-edge technology such as laser micro-machining, nano-electronics, free-space optical telecommunications and for industrial applications in the areas of aeronautics and aerodynamics. Non-equilibrium turbulent processes are anisotropic, non-local, multi-scale and multi-phase, and often are driven by shocks or acceleration. Their scaling, spectral and invariant properties differ substantially from those of classical Kolmogorov turbulence. At atomistic and meso-scales, the non-equilibrium dynamics depart dramatically from a standard scenario given by Gibbs statistic ensemble average and quasi-static Boltzmann equation. The singular aspect and the similarity of the non-equilibrium dynamics at macroscopic scales are interplayed with the fundamental properties of the Euler and compressible Navier-Stokes equations and with the problem sensitivity to the boundary conditions at discontinuities. The state-of-the-art numerical simulations of multi-phase flows suggest new methods for predictive modelling of the multi-scale non-equilibrium dynamics in fluids and plasmas, for error estimates and uncertainty quantifications, as well as for novel data assimilation techniques. 3. International Conference 'Turbulent Mixing and Beyond' The First and Second International Conferences on Turbulent Mixing and Beyond found that: (i) TMB-related problems have in common a set of outstanding research issues; (ii) their solution has a potential to significantly advance a variety of disciplines in science, technology and mathematics; (iii) TMB participants conduct highly innovative research and their

  12. The 1991 3rd NASA Symposium on VLSI Design

    NASA Technical Reports Server (NTRS)

    Maki, Gary K.

    1991-01-01

    Papers from the symposium are presented from the following sessions: (1) featured presentations 1; (2) very large scale integration (VLSI) circuit design; (3) VLSI architecture 1; (4) featured presentations 2; (5) neural networks; (6) VLSI architectures 2; (7) featured presentations 3; (8) verification 1; (9) analog design; (10) verification 2; (11) design innovations 1; (12) asynchronous design; and (13) design innovations 2.

  13. Legal Concepts in Sport: A Primer. 3rd Edition

    ERIC Educational Resources Information Center

    Carpenter, Linda Jean

    2008-01-01

    When most people think of legal issues in sport, they think about negligence. However, most professionals will face a much broader range of issues. For instance, topics such as sexual harassment, corporal punishment, drug testing, transportation, and hazing are all of special importance today. Also anti-discrimination laws and the concepts…

  14. Learning in Adulthood: A Comprehensive Guide, 3rd Edition

    ERIC Educational Resources Information Center

    Merriam, Sharan B.; Caffarella, Rosemary S.; Baumgartner, Lisa M.

    2006-01-01

    In this updated landmark book, the authors have gathered the seminal work and most current thinking on adult learning into one volume. This book addresses a wide range of topics including: Who are adult learners? How do adults learn? Why are adults involved in learning activities? How does the social context shape the learning that adults are…

  15. Basic imaging in congenital heart disease. 3rd Ed

    SciTech Connect

    Swischuk, L.E.; Sapire, D.W.

    1986-01-01

    The book retains its previous format with chapters on embryology, plain film interpretation, classification of pulmonary vascular patterns, cardiac malpositions and vascular anomalies, and illustrative cases. The book is organized with an abundance of illustrative figures, diagrams, and image reproductions. These include plain chest radiographs, angiograms, echocardiograms, and MR images. The authors present the pathophysiology and imaging of congenital heart lesions.

  16. Hospitals, nursing homes turn to 3rd-party financing

    SciTech Connect

    Slaff, J.

    1982-07-05

    Experience is teaching the administrators of hospitals and nursing homes how to make better arrangements for third-party financing of energy-management systems. Accustomed to health-insurance reimbursement for health-care costs, hospitals have lacked incentives for conservation. Plans now used most by hospitals and health-care facilities involve third-party arrangements where: (1) an equipment vendor installs equipment and takes a share of the energy-cost savings; or (2) energy-services firms both install capital-intensive equipment and implement a variety of low-cost conservation measures, again for a percentage of the savings. Although most users think these arrangements are satisfactory, they advise a preliminary low-cost audit and participation in a basic energy-management seminar before employing an energy-services firm. Accurate baseline energy-consumption data should be developed in order to evaluate results, and assurance is needed that staff members understand the accounting formulas. Also recommended are independent audits after installation and attention to the legal clauses in contracts. (DCK)

  17. In Search of a Future. 3rd Edition, November 1976.

    ERIC Educational Resources Information Center

    Fulham, Stanley A.

    Describing the increasing numbers of Canada Natives who must reconcile the conflict arising from the economic necessity to migrate and the emotional necessity to stay in Manitoba's rural areas, this book identifies the following problems facing the rural to urban Canada Native migrant: lack of adequate housing; lack of finances; deficiency in…

  18. Resource Guide to Careers in Toxicology, 3rd Edition.

    ERIC Educational Resources Information Center

    Society of Toxicology, Reston, VA.

    This resource guide was prepared by the Tox 90's Educational Issues Task Force of the Society of Toxicology. The introduction provides information on the Society of Toxicology and financial support for graduate students in toxicology. Other sections include career opportunities in toxicology, academic and postdoctoral programs in toxicology, and…

  19. Contraceptive social marketing: a continuous cycle of planning, testing and evaluating.

    PubMed

    1985-01-01

    This article outlines the contraceptive marketing process used by the Social Marketing for Change (SOMARC) project. The 1st stage of the process involves analysis of the market, the consumer, and the social marketing organization's capabilities. In the 2nd stage, planning, data collected in the analysis stage are used to define objectives, segment target markets, and devise strategies for each element in the marketing mix. In the 3rd stage, all the elements in the marketing mix are developed and tested (e.g. product concepts, pricing, packaging, communication messages) and refined on the basis of test results. In stage 4, the action plan is implemented and marketing progress and institutional performance are monitored. Stage 5 includes an assessment of in-market effectiveness in terms of responses from consumers, retailers, and health professionals. The last stage feeds back to the 1st. All the reviewed data are recycled into analysis to begin again the continuous process of refinement and improvement.

  20. Promoting networks between evidence-based medicine and values-based medicine in continuing medical education

    PubMed Central

    2013-01-01

    Background In recent years, medical practice has followed two different paradigms: evidence-based medicine (EBM) and values-based medicine (VBM). There is an urgent need to promote medical education that strengthens the relationship between these two paradigms. This work is designed to establish the foundations for a continuing medical education (CME) program aimed at encouraging the dialogue between EBM and VBM by determining the values relevant to everyday medical activities. Methods A quasi-experimental, observational, comparative, prospective and qualitative study was conducted by analyzing through a concurrent triangulation strategy the correlation between healthcare personnel-patient relationship, healthcare personnel's life history, and ethical judgments regarding dilemmas that arise in daily clinical practice. In 2009, healthcare personnel working in Mexico were invited to participate in a free, online clinical ethics course. Each participant responded to a set of online survey instruments before and after the CME program. Face-to-face semi-structured interviews were conducted with healthcare personnel, focusing on their views and representations of clinical practice. Results The healthcare personnel's core values were honesty and respect. There were significant differences in the clinical practice axiology before and after the course (P <0.001); notably, autonomy climbed from the 10th (order mean (OM) = 8.00) to the 3rd position (OM = 5.86). In ethical discernment, the CME program had an impact on autonomy (P ≤0.0001). Utilitarian autonomy was reinforced in the participants (P ≤0.0001). Regarding work values, significant differences due to the CME intervention were found in openness to change (OC) (P <0.000), self-transcendence (ST) (P <0.001), and self-enhancement (SE) (P <0.019). Predominant values in life history, ethical discernment and healthcare personnel-patient relation were beneficence, respect and compassion, respectively. Conclusions The

  1. Periodontal healing two and four years after impacted lower third molar surgery. A comparative retrospective study.

    PubMed

    Kugelberg, C F

    1990-12-01

    The long-term effects on periodontal tissues of impacted lower 3rd molar surgery have been investigated in a retrospective study comprising 51 cases. The postoperative examinations took place 2 and 4 years after the surgical treatment and included both clinical and radiographic variables. Assessments were made regarding the oral hygiene status, gingival condition and periodontal tissue breakdown in terms of increased probing depths and intrabony defects. Comparing the results of the two examinations, no significant changes of the incidence of plaque and gingivitis were seen on the distal surface of the 2nd molar, nor any significant change concerning the probing depth. The proximal bone level distal to the second molar was recorded by radiographic examination with a cut-off periodontal probe as indicator. Two years postoperatively, 16.7% of the cases aged less than or equal to 25 years showed intrabony defects exceeding 4 mm, compared with 40.7% in the age group greater than or equal to 26 years. At the 4-year re-examination, the corresponding figures were 4.2% and 44.4%, respectively. The improvement concerning the alveolar bone level was mainly seen in individuals under 25 years. Some factors affecting the periodontal healing after impacted lower 3rd molar surgery are discussed. PMID:2128310

  2. "Bone-οn-Bone" surgical reconstruction of moderate severity, flexible single curve adolescent idiopathic scoliosis: continuing improvements of the technique and results in three scoliosis centers after almost twenty years of use.

    PubMed

    Gaines, Robert W; Min, Kan; Zarzycki, Daniel

    2015-01-01

    The "bone-on-bone" reconstruction for adolescent idiopathic scoliosis is reviewed in this article. Extensive use over the past 18 years has identified it's functional benefits outstanding clinical results, and very limited complications. This is an extensive update of it's application, since it's introduction, 18 years ago. PMID:26000031

  3. Continuous steam explosion

    SciTech Connect

    Taylor, J.D.; Yu, E.K.C.

    1995-02-01

    StakeTech has focused on developing steam explosion on a commercial basis. The company essentially a biomass conversion company dealing with cellulosic biomass such as wood, crop residues and, more recently, wastepaper and municipal solid waste (MSW). They are faced with a tremendous opportunity to develop uses for the 50% of biomass that is currently wasted. The StakeTech steam explosion process is able to break the bonds using only high-pressure steam with no chemical additives. The continuous StakeTech System now has been installed in five countries and has proved effective in processing a wide variety of raw materials including wood chips, straw, sugarcane bagasse, and waste paper. End-use applications range from specialty chemicals to large-volume agricultural products. The increase of development activities in steam explosion should lead to expanded end-use applications, and acceptance of the technology by industry should accelerate in the years to come.

  4. Baseline budgeting for continuous improvement.

    PubMed

    Kilty, G L

    1999-05-01

    This article is designed to introduce the techniques used to convert traditionally maintained department budgets to baseline budgets. This entails identifying key activities, evaluating for value-added, and implementing continuous improvement opportunities. Baseline Budgeting for Continuous Improvement was created as a result of a newly named company president's request to implement zero-based budgeting. The president was frustrated with the mind-set of the organization, namely, "Next year's budget should be 10 to 15 percent more than this year's spending." Zero-based budgeting was not the answer, but combining the principles of activity-based costing and the Just-in-Time philosophy of eliminating waste and continuous improvement did provide a solution to the problem.

  5. Continuing Change after the Innovation

    ERIC Educational Resources Information Center

    Todd, R. Watson

    2006-01-01

    Focusing on the implementation of a task-based curriculum at a Thai university, this paper examines the continuation stage of the innovation by looking at how and why the curriculum has changed in its first four years. Based on course documentation and teacher interviews, the major changes to the curriculum were a reduction in the number of tasks,…

  6. Continuing professional development for veterinarians.

    PubMed

    Caple, I W

    2005-04-01

    Continuing professional development for veterinarians is expected to commence in the year after graduation and continue until retirement. The World Organisation for Animal Health standard for veterinary services is based on principles of an ethical, organisational and technical nature, and a mix of regulation, self-regulation and quality assurance approaches are used. Few jurisdictions have made a minimum requirement of continuing professional development, measured in hours or units, mandatory in 2004, however, there is an increasing expectation of veterinarians to keep a personal record of their continuing professional development activities. Such records might assist in defending complaints about professional misconduct, and provide a basis for planning and monitoring personal professional growth. Continuing professional development can be obtained by a variety of means through structured and unstructured learning activities. The rapid advances in communication technologies and ready access to available electronic databases at the beginning of the 21st century is rapidly changing the way students learn in veterinary schools and how they will acquire continuing professional development during their careers. Universities, governments, professional associations and special interest groups all have roles to play in the delivery of continuing professional development to the veterinary profession and to ensure a structure is in place to monitor improvements in the delivery of quality veterinary services. PMID:15907035

  7. An Approach to Find out Students' Motives and Influences on Their Selection of Studies and University: Results from Six Years of Continuous Institutional Research in a Multi-Campus System in Spain

    ERIC Educational Resources Information Center

    Gallifa, Josep

    2009-01-01

    This paper presents an institutional research on service quality conducted to analyze the students' motives and influences on their selection of studies and university. The research was carried out by collecting data from first-year students in a multi-campus system where institutions are independent in their recruitment strategies. Results from…

  8. Promoting Original Scientific Research and Teacher Training Through a High School Science Research Program: A Five Year Retrospective and Analysis of the Impact on Mentored 8th Grade Geoscience Students and the Mentors Themselves

    NASA Astrophysics Data System (ADS)

    Danch, J. M.

    2015-12-01

    In 2010 a group of 8th grade geoscience students participated in an extracurricular activity allowing them to conduct original scientific research while being mentored by students enrolled in a 3 - year high school Science Research program. Upon entering high school the mentored students themselves enrolled in the Science Research program and continued for 4 years, culminating with their participation in Science Research 4. This allowed them to continue conducting original scientific research, act as mentors to 8th grade geoscience students and to provide teacher training for both middle and high school teachers conducting inquiry-based science lessons. Of the 7 Science Research 4 students participating since 2010, 100% plan on majoring or minoring in a STEM - related field in college and their individual research projects have been been granted over 70 different awards and honors in science fair and symposia including a 3rd and 4th place category awards at two different international science fairs - the International Sustainable Energy Engineering and Environment Project (iSWEEP) and the International Science and Engineering Fair (ISEF). Science Research 4 students developed and conducted a Society for Science and the Public affiliated science fair for middle school students enrolled in an 8th grade honors geoscience program allowing over 100 students from 5 middle schools to present their research and be judged by STEM professionals. Students with research judged in the top 10% were nominated for participation in the National Broadcom MASTERS program which they successfully entered upon further mentoring from the Science Research 4 students. 8th grade enrollment in the Science Research program for 2015 increased by almost 50% with feedback from students, parents and teachers indicating that the mentorship and participation in the 8th grade science fair were factors in increasing interest in continuing authentic scientific research in high school.

  9. Continuing Liberal Education. Continuing Higher Education Series.

    ERIC Educational Resources Information Center

    House, David B.

    This book investigates the key areas of nontraditional education program planning and development by examining the ways that liberal arts programs at various institutions have been academically and administratively established, developed, and maintained. Areas examined are the following: (1) the history of continuing liberal education and the…

  10. A Guide for Parents and Families about What Your 3rd Grader Should Be Learning in School This Year. Don't Fail Your Children = Una Guia para los Padres y Familias Acerca de Lo Que Su Hijo de 3er Grado Debe Aprender en la Escuela Este Ano. No Le Falle a Sus Hijos.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia.

    This guide, in English- and Spanish-language versions, shares with parents information about the South Carolina Curriculum Standards. The standards outline state requirements for children's learning and what students across the state should be able to do in certain subjects. The guide lists seven key reasons parents should be aware of the new…

  11. Continuity of Care

    PubMed Central

    Alazri, Mohammed; Heywood, Philip; Neal, Richard D; Leese, Brenda

    2007-01-01

    Continuity of care is widely regarded as a core value of primary care. The objective of this article is to explore the literature about the concept of continuity of care focusing on factors that influence continuity; advantages and disadvantages of continuity and the effect of continuity on outcomes, hence on the quality of care. Electronic databases and other websites were searched for relevant literature. The results of this review showed that continuity of care is influenced by demographic factors, factors related to patients and healthcare professionals, patient-healthcare professional relationship, inter-professional factors, role of receptionists and organisational factors. Several advantages were found to be associated with most types of continuity in various medical disciplines preventive medicine, general health, maternity and child health, mental and psychosocial health, chronic diseases and costs of care.Various factors influenced different types of continuity. Most types of continuity were associated with good outcomes, hence indirectly affecting the quality of care. Health care professionals and policy makers should be aware of the effect of continuity on quality of care and of the factors that influence continuity if they wish to preserve it as a core value of primary care. PMID:21748104

  12. The experience of the FERMI@Elettra photon beam transport and diagnostics system (PADReS) during three years of continuous support of machine and user experiments: achievements, lessons learned, and future upgrades

    NASA Astrophysics Data System (ADS)

    Zangrando, Marco; Fava, Claudio; Gerusina, Simone; Gobessi, Riccardo; Mahne, Nicola; Mazzucco, Eric; Raimondi, Lorenzo; Rumiz, Luca; Svetina, Cristian

    2014-09-01

    The FERMI FEL facility has begun delivering photons in 2011, becoming in late 2012 the first seeded facility open to external users worldwide. Since then, several tens of experiments have been carried out on the three operative endstations LDM, DiProI, and EIS-TIMEX. Starting from the commissioning phase, the transport and diagnostics system (PADReS) has been continuously developed and upgraded, becoming the indispensable interface between the machine and the experimental chambers. Moreover, PADReS itself has served as an active player for several machine studies as well as for various state-of-the-art experiments. In particular, some elements of PADReS have become key features to perform cutting edge experiments: the online energy spectrometer, the active optics refocusing systems, the split and delay line, and so on. For each of them the peculiar advantages will be described showing the actual implementation in the experiments. The experience gathered so far in fulfilling the needs of both machine and experimental physicists will be discussed, with particular emphasis on the solutions adopted in different scenarios. Recurrent requests and major difficulties will be reported so to give a glimpse about the standard tasks to be solved when preparing new and demanding experiments. Finally, some ideas and near-future improvements will be presented and discussed.

  13. A 3-year randomized clinical trial evaluating two different bonded posterior restorations: Amalgam versus resin composite

    PubMed Central

    Kemaloglu, Hande; Pamir, Tijen; Tezel, Huseyin

    2016-01-01

    Objective: To compare the performance and postoperative sensitivity of a posterior resin composite with that of bonded amalgam in 40 (n = 20) large sized cavities and to evaluate whether resin composite could be an alternative for bonded amalgam. Materials and Methods: This was a randomized clinical trial. Twenty patients in need of at least two posterior restorations were recruited. Authors randomly assigned one half of the restorations to receive bonded amalgam and the other half to composite restorations. Forty bonded amalgams (n = 20) and composites (n = 20) were evaluated for their performance on modified-US Public Health Service criteria and postoperative sensitivity using visual analogue scale (VAS) for 36-months. Results: Success rate of this study was 100%. First clinical alterations were rated as Bravo after 1 year in marginal discoloration, marginal adaptation, anatomical form, and surface roughness for both amalgam and composite. At the 3rd year, overall “Bravo” rated restorations were 12 for bonded amalgam and 13 for resin composites. There were no significant differences among the VAS scores of composites and bonded amalgams for all periods (P > 0.05) except for the comparisons at the 3rd year evaluation (P < 0.05). Conclusions: Within the limitation of this study, both resin composite and bonded amalgam were clinically acceptable. Postoperative sensitivity results tend to decrease more in composite restorations rather than amalgams. Therefore, it was concluded that posterior resin composite can be used even in large sized cavities. PMID:27011734

  14. Evaluating lake stratification and temporal trends by using near-continuous water-quality data from automated profiling systems for water years 2005-09, Lake Mead, Arizona and Nevada

    USGS Publications Warehouse

    Veley, Ronald J.; Moran, Michael J.

    2012-01-01

    The U.S. Geological Survey, in cooperation with the National Park Service and Southern Nevada Water Authority, collected near-continuous depth-dependent water-quality data at Lake Mead, Arizona and Nevada, as part of a multi-agency monitoring network maintained to provide resource managers with basic data and to gain a better understanding of the hydrodynamics of the lake. Water-quality data-collection stations on Lake Mead were located in shallow water (less than 20 meters) at Las Vegas Bay (Site 3) and Overton Arm, and in deep water (greater than 20 meters) near Sentinel Island and at Virgin and Temple Basins. At each station, near-continual depth-dependent water-quality data were collected from October 2004 through September 2009. The data were collected by using automatic profiling systems equipped with multiparameter water-quality sondes. The sondes had sensors for temperature, specific conductance, dissolved oxygen, pH, turbidity, and depth. Data were collected every 6 hours at 2-meter depth intervals (for shallow-water stations) or 5-meter depth intervals (for deep-water stations) beginning at 1 meter below water surface. Data were analyzed to determine water-quality conditions related to stratification of the lake and temporal trends in water-quality parameters. Three water-quality parameters were the main focus of these analyses: temperature, specific conductance, and dissolved oxygen. Statistical temporal-trend analyses were performed for a single depth at shallow-water stations [Las Vegas Bay (Site 3) and Overton Arm] and for thermally-stratified lake layers at deep-water stations (Sentinel Island and Virgin Basin). The limited period of data collection at the Temple Basin station prevented the application of statistical trend analysis. During the summer months, thermal stratification was not observed at shallow-water stations, nor were major maxima or minima observed for specific-conductance or dissolved-oxygen profiles. A clearly-defined thermocline

  15. Volcano-tectonic deformation in the Kivu Region, Central Africa: Results from multi-year InSAR time series analysis and continuous GNSS observations of the Kivu Geodetic Network (KivuGNet)

    NASA Astrophysics Data System (ADS)

    Geirsson, Halldor; D'Oreye, Nicolas; Smets, Benoît; Nobile, Adriano; Samsonov, Sergey; De Rauw, Dominique; Mashagiro, Niche; Kervyn, Francois

    2016-04-01

    The Kivu Region in Central Africa is a topographic dome cut by the depression of the western branch of the East African Rift, where the Nubia plate and the Victoria micro-plate are diverging by approximately 2-3 mm/yr (Stamps et al. 2008). Two closely spaced and frequently active volcanoes, Nyiragongo and Nyamulagira, are located at the plate boundary. Here, deformation signals from transient deformation events (i.e. earthquakes, eruptions, rifting episodes, intrusions or other subsurface mass movements) are intertwined with the more perpetual nature of inter-seismic strain accumulation and gradual magma accumulation. Here, we present deformation results from six years of operation of the 15- station KivuGNet (Kivu Geodetic Network) in the Kivu Region and multi-year InSAR time series of the region using the MSBAS approach (Samsonov & d'Oreye, 2012). Since 2009, KivuGNet has captured transient deformation from a) the 2010 eruption of Nyamulagira, b) the 2011-2012 eruption of Nyamulagira c) the Mw5.8 August 7, 2015 Katana earthquake at the western border of Lake Kivu. Importantly, the GPS data also show an ongoing deformation signal, which is most readily explained by long-term magma accumulation under the volcanic region. We use the GPS and InSAR deformation signals to constrain and compare source parameters of simplistic elastic models for the different time periods. Although not well constrained, most of the time periods indicate the presence of a deep (~15-30 km) magmatic source centered approximately under Nyamulagira or to the southeast of Nyamulagira, that inflates between eruptions and deflates during eruptions.

  16. Overview 2003 of NASA Multi-D Stirling Convertor Development and DOE and NASA Stirling Regenerator R and D Efforts

    NASA Technical Reports Server (NTRS)

    Twe, Roy; Ibrahim, Mounir; Simon, Terrence; Mantell, Susan; Gedeon, David; Qiu, Songgang; Wood, Gary

    2004-01-01

    This paper will report on (1) continuation through the 3rd year of a NASA grant for multi-dimensional Stirling CFD code development and validation, (2) continuation through the 3rd and final year of a Department of Energy, Golden Field Office (DOE) regenerator research effort. Results of the NASA multi-D code development effort and the DOE regenerator research efforts will be summarized. Early results and planning for the new regenerator microfabrication contract will also be discussed.

  17. Construction costs continue slow increase

    SciTech Connect

    Morgan, J.M.

    1986-03-31

    Oil-pipeline construction costs for third quarter 1985, as measured by the OGJ-Morgan Pipeline Cost Index, continued the moderation evident in the year's first half. Although some cost elements showed signs of moving ahead at a faster clip during the quarter, the primary forces holding down inflation, especially moderate labor increases and competitive material prices, appeared stronger than ever. The worldwide oil glut, which had been keeping a cap on oil energy costs, was expected to continue. And some economists in the quarter were even then predicting a major crude oil price cut by the end of 1985. Furthermore, the cost of borrowing construction funds remained at its lowest level in years. The composite cost index for building oil pipelines showed a minor increase of 0.45% during third quarter 1985.

  18. Influence of post-harvest crop residue fires on surface ozone mixing ratios in the N.W. IGP analyzed using 2 years of continuous in situ trace gas measurements

    NASA Astrophysics Data System (ADS)

    Kumar, V.; Sarkar, C.; Sinha, V.

    2016-04-01

    O3, CO, and NOx affect air quality and tropospheric chemistry but factors that control them in the densely populated N.W. Indo-Gangetic Plain (IGP) are poorly understood. This work presents the first simultaneous 2 year long in situ data set acquired from August 2011 to September 2013 at a N.W. IGP site (30.667°N, 76.729°E; 310 m asl). We investigate the impact of emissions and meteorology on the diel and seasonal variability of O3, CO, and NOx. Regional post-harvest crop residue fires contribute majorly to an enhancement of 19 ppb in hourly averaged ozone concentrations under similar meteorological conditions in summer and 7 ppb under conditions of lower radiation during the post monsoon. d[O3]/dt (from sunrise to daytime O3 maxima) was highest during periods influenced by post-harvest fires in post monsoon season (9.2 ppb h-1) and lowest during monsoon season (4.1 ppb h-1). Analysis of air mass clusters revealed that enhanced chemical formation of O3 and not transport was the driver of the summertime and post monsoon ambient O3 maxima. Despite having high daytime NOx (>12 ppb) and CO (>440 ppb) in winter, average daytime O3 was less than 40 ppb due to reduced photochemistry and fog. Average daytime O3 during the monsoon was less than 45 ppb due to washout of precursors and suppressed photochemistry due to cloud cover. The 8 h ambient air quality O3 standard was violated on 451 days in the period August 2011-September 2013. The results show that substantial mitigation efforts are required to reduce regional O3 pollution in the N.W. IGP.

  19. Planning for Project Continuation.

    ERIC Educational Resources Information Center

    Berry, Grant, Jr.

    Designed to help colleges plan for the successful continuation of educational improvement projects beyond the end of their original funding period, this report presents a case study of Pennsylvania College of Technology's (PCT's) efforts to ensure the continuation of a Title III faculty development program. After describing the the Title III…

  20. Library of Continuation Algorithms

    2005-03-01

    LOCA (Library of Continuation Algorithms) is scientific software written in C++ that provides advanced analysis tools for nonlinear systems. In particular, it provides parameter continuation algorithms. bifurcation tracking algorithms, and drivers for linear stability analysis. The algorithms are aimed at large-scale applications that use Newton’s method for their nonlinear solve.