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Sample records for 3s3p 1p1 state

  1. Photoionization cross sections of the excited 3s3p 3Po state for atomic Mg

    NASA Astrophysics Data System (ADS)

    Wang, Guoli; Wan, Jianjie; Zhou, Xiaoxin

    2017-01-01

    The photoionization cross sections of the excited levels (3s3p 0,1,2,o 3P) of atomic Mg have been studied theoretically using both the nonrelativistic and fully relativistic R-matrix method. For the threshold cross sections, as previous nonrelativistic studies, present calculations show significant differences (a factor of 3) from former experimental values. Large discrepancies with experiment calls for additional measurements of the photoionization cross sections from the excited states of Mg.

  2. Simultaneous ionization-excitation of helium to the 3s, 3p, and 3d states of He+

    NASA Astrophysics Data System (ADS)

    Zatsarinny, Oleg; Bartschat, Klaus

    2015-05-01

    We extended our work on ionization of helium with simultaneous excitation to the n = 2 states to include the n = 3 manifold of the residual ion. This requires the inclusion of pseudo-states constructed on the 3s, 3p, and 3d ionic core. We used a parallelized version of the B-spline R-matrix (BSR) package to perform a calculation with 1,254 target states, resulting in up to 3,027 coupled channels and matrices of rank up to 200,000 to be diagonalized. The triple-differential cross section (TDCS) was extracted by the projection method. We obtain excellent agreement with experiment regarding the angular dependence of the TDCS for all kinematical situations available for comparison. Some discrepancies remain for the absolute magnitude. Results for the n = 2 states are stable and closely agree with previous predictions. Work supported by the United States National Science Foundation under grants No. PHY-1212450, PHY-1430245 and the XSEDE allocation PHY-090031.

  3. Precision measurement of the mass of the hc(1P1) state of charmonium.

    PubMed

    Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; Lopez, A; Mendez, H; Ramirez, J; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P

    2008-10-31

    A precision measurement of the mass of the h_{c}(1P1) state of charmonium has been made using a sample of 24.5x10;{6} psi(2S) events produced in e;{+}e;{-} annihilation at the Cornell Electron Storage Ring (CESR). The reaction used was psi(2S)-->pi;{0}h_{c}, pi;{0}-->gammagamma, h_{c}-->gammaeta_{c}, and the reaction products were detected in the CLEO-c detector. Data have been analyzed both for the inclusive reaction and for the exclusive reactions in which eta_{c} decays are reconstructed in 15 hadronic decay channels. Consistent results are obtained in the two analyses. The averaged results of the present measurements are M(h_{c})=3525.28+/-0.19(stat.)+/-0.12(syst.) MeV, and B(psi(2S)-->pi;{0}h_{c})xB(h_{c}-->gammaeta_{c})=(4.19+/-0.32+/-0.45)x10;{-4}. Using the ;{3}P_{J} centroid mass, DeltaM_{hf}(1P) identical withM(chi_{cJ})-M(h_{c})=+0.02+/-0.19+/-0.13 MeV.

  4. Radiative lifetime of the 3s3p exp 3(exp 5 S sub 2 exp 0) metastable level of P(+)

    NASA Technical Reports Server (NTRS)

    Calamai, Anthony G.; Han, Xiaofeng; Parkinson, William H.

    1992-01-01

    The present experimental and theoretical results for the radiative lifetime of the 3s3p exp 3(exp 5 S sub 2 exp 0) metastable level of P(+) encompass an experimental determination of the (exp 5 S sub 2 exp 0) lifetime which represents the first measured lifetime of a low charge-state ion in the Si I sequence. This constitutes a fundamental test of the theoretical methods used to determine transition possibilities for intercombination lines involving this level, and suggests that theoretical techniques used to determine such transition probabilities in low-Z species of the Si I isoelectronic sequence should be reevaluated.

  5. Transition probabilities for the 3s2 3p(2P0)-3s3p2(4P) intersystem lines of Si II

    NASA Technical Reports Server (NTRS)

    Calamai, Anthony G.; Smith, Peter L.; Bergeson, S. D.

    1993-01-01

    Intensity ratios of lines of the spin-changing 'intersystem' multiplet of S II (4P yields 2P0) at 234 nm have been used to determine electron densities and temperatures in a variety of astrophysical environments. However, the accuracy of these diagnostic calculations have been limited by uncertainties associated with the available atomic data. We report the first laboratory measurement, using an ion-trapping technique, of the radiative lifetimes of the three metastable levels of the 3s3p2 4P term of Si II. Our results are 104 +/- 16, 406 +/- 33, and 811 +/- 77 micro-s for lifetimes of the J = 1/2, 5/2, and 3/2 levels, respectively. A-values were derived from our lifetimes by use of measured branching fractions. Our A-values, which differ from calculated values by 30 percent or more, should give better agreement between modeled and observed Si II line ratios.

  6. Evaluation of electron population terms for 4p, 3S>3p, and (2p): how do HOMO and LUMO shrink or expand depending on nuclear charges?

    PubMed

    Nakanishi, Waro; Hayashi, Satoko; Narahara, Kenji; Yamaki, Daisuke; Hada, Masahiko

    2008-01-01

    Electron population terms are evaluated for N=Se, S, and O. Calculations are performed on HOMO and LUMO constructed by pure atomic 4p(Se), 3p(S), and 2p(O) orbitals, employing the 6-311+G(3d) and/or 6-311(++)G(3df,3pd) basis sets at the HF, MP2, and DFT (B3 LYP) levels. Se(4+), Se(2+), Se(0), and Se(2-) with the O(h) symmetry are called G(A: Se) and HSe(+), H(2)Se, and HSe(-) with the C(infinityh) or C(2v) symmetry are named G(B: Se), here [G(A+B: Se) in all]. HOMO and LUMO in G(A+B: N) (N=Se, S, and O) satisfy the conditions of the calculations for . The (4p), 3)S>(3p), and (2p) values correlate well with the corresponding MO energies (epsilon(N)) for all calculation levels employed. Plots of (HOMO) and (LUMO) versus Q(N) (N=Se, S, and O) at the HF and MP2 levels are analyzed as two correlations. However, the plots at the DFT level can be analyzed as single correlation. A regression curve is assumed for the analysis. Behaviors of clarify how valence orbitals shrink or expand depending on Q(N). The applicability of is examined to establish a new method that enables us to analyze chemical shifts with the charge effect separately from others. A utility program derived from the Gaussian 03 (NMRANAL-NH03G) is applied to evaluate and examine the applicability to the NMR analysis.

  7. Transcriptional Auto-Regulation of RUNX1 P1 Promoter.

    PubMed

    Martinez, Milka; Hinojosa, Marcela; Trombly, Daniel; Morin, Violeta; Stein, Janet; Stein, Gary; Javed, Amjad; Gutierrez, Soraya E

    2016-01-01

    RUNX1 a member of the family of runt related transcription factors (RUNX), is essential for hematopoiesis. The expression of RUNX1 gene is controlled by two promoters; the distal P1 promoter and the proximal P2 promoter. Several isoforms of RUNX1 mRNA are generated through the use of both promoters and alternative splicing. These isoforms not only differs in their temporal expression pattern but also exhibit differences in tissue specificity. The RUNX1 isoforms derived from P2 are expressed in a variety of tissues, but expression of P1-derived isoform is restricted to cells of hematopoietic lineage. However, the control of hematopoietic-cell specific expression is poorly understood. Here we report regulation of P1-derived RUNX1 mRNA by RUNX1 protein. In silico analysis of P1 promoter revealed presence of two evolutionary conserved RUNX motifs, 0.6kb upstream of the transcription start site, and three RUNX motifs within 170bp of the 5'UTR. Transcriptional contribution of these RUNX motifs was studied in myeloid and T-cells. RUNX1 genomic fragment containing all sites show very low basal activity in both cell types. Mutation or deletion of RUNX motifs in the UTR enhances basal activity of the RUNX1 promoter. Chromatin immunoprecipitation revealed that RUNX1 protein is recruited to these sites. Overexpression of RUNX1 in non-hematopoietic cells results in a dose dependent activation of the RUNX1 P1 promoter. We also demonstrate that RUNX1 protein regulates transcription of endogenous RUNX1 mRNA in T-cell. Finally we show that SCL transcription factor is recruited to regions containing RUNX motifs in the promoter and the UTR and regulates activity of the RUNX1 P1 promoter in vitro. Thus, multiple lines of evidence show that RUNX1 protein regulates its own gene transcription.

  8. Sphingosine 1-phosphate receptor 1 (S1P(1)) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P(1) antagonist.

    PubMed

    Cahalan, Stuart M; Gonzalez-Cabrera, Pedro J; Nguyen, Nhan; Guerrero, Miguel; Cisar, Elizabeth A George; Leaf, Nora B; Brown, Steven J; Roberts, Edward; Rosen, Hugh

    2013-02-01

    Sphingosine 1-phosphate receptor 1 (S1P(1)) is a G protein-coupled receptor that is critical for proper lymphocyte development and recirculation. Agonists to S1P(1) are currently in use clinically for the treatment of multiple sclerosis, and these drugs may act on both S1P(1) expressed on lymphocytes and S1P(1) expressed within the central nervous system. Agonists to S1P(1) and deficiency in S1P(1) both cause lymphocyte sequestration in the lymph nodes. In the present study, we show that S1P(1) antagonism induces lymphocyte sequestration in the lymph nodes similar to that observed with S1P(1) agonists while upregulating S1P(1) on lymphocytes and endothelial cells. Additionally, we show that S1P(1) antagonism reverses experimental autoimmune encephalomyelitis in mice without acting on S1P(1) expressed within the central nervous system, demonstrating that lymphocyte sequestration via S1P(1) antagonism is sufficient to alleviate autoimmune pathology.

  9. Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.

    PubMed

    Vachal, Petr; Toth, Leslie M; Hale, Jeffrey J; Yan, Lin; Mills, Sander G; Chrebet, Gary L; Koehane, Carol A; Hajdu, Richard; Milligan, James A; Rosenbach, Mark J; Mandala, Suzanne

    2006-07-15

    Novel series of sphingosine-1-phosphate (S1P) receptor agonists were developed through a systematic SAR aimed to achieve high selectivity for a single member of the S1P family of receptors, S1P1. The optimized structure represents a highly S1P1-selective and efficacious agonist: S1P1/S1P2, S1P1/S1P3, S1P1/S1P4>10,000-fold, S1P1/S1P5>600-fold, while EC50 (S1P1) <0.2 nM. In vivo experiments are consistent with S1P1 receptor agonism alone being sufficient for achieving desired lymphocyte-lowering effect.

  10. Discovery of a novel series of potent S1P1 agonists.

    PubMed

    Crosignani, Stefano; Bombrun, Agnes; Covini, David; Maio, Maurizio; Marin, Delphine; Quattropani, Anna; Swinnen, Dominique; Simpson, Don; Sauer, Wolfgang; Françon, Bernard; Martin, Thierry; Cambet, Yves; Nichols, Anthony; Martinou, Isabelle; Burgat-Charvillon, Fabienne; Rivron, Delphine; Donini, Cristina; Schott, Olivier; Eligert, Valerie; Novo-Perez, Laurence; Vitte, Pierre-Alain; Arrighi, Jean-François

    2010-03-01

    The discovery of a novel series of S1P1 agonists is described. Starting from a micromolar HTS positive, iterative optimization gave rise to several single-digit nanomolar S1P1 agonists. The compounds were able to induce internalization of the S1P1 receptor, and a selected compound was shown to be able to induce lymphopenia in mice after oral dosing.

  11. Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism

    PubMed Central

    Bigaud, Marc; Dincer, Zuhal; Bollbuck, Birgit; Dawson, Janet; Beckmann, Nicolau; Beerli, Christian; Fishli-Cavelti, Gina; Nahler, Michaela; Angst, Daniela; Janser, Philipp; Otto, Heike; Rosner, Elisabeth; Hersperger, Rene; Bruns, Christian; Quancard, Jean

    2016-01-01

    Rational Homeostasis of vascular barriers depends upon sphingosine 1-phosphate (S1P) signaling via the S1P1 receptor. Accordingly, S1P1 competitive antagonism is known to reduce vascular barrier integrity with still unclear pathophysiological consequences. This was explored in the present study using NIBR-0213, a potent and selective S1P1 competitive antagonist. Results NIBR-0213 was tolerated at the efficacious oral dose of 30 mg/kg BID in the rat adjuvant-induced arthritis (AiA) model, with no sign of labored breathing. However, it induced dose-dependent acute vascular pulmonary leakage and pleural effusion that fully resolved within 3–4 days, as evidenced by MRI monitoring. At the supra-maximal oral dose of 300 mg/kg QD, NIBR-0213 impaired lung function (with increased breathing rate and reduced tidal volume) within the first 24 hrs. Two weeks of NIBR-0213 oral dosing at 30, 100 and 300 mg/kg QD induced moderate pulmonary changes, characterized by alveolar wall thickening, macrophage accumulation, fibrosis, micro-hemorrhage, edema and necrosis. In addition to this picture of chronic inflammation, perivascular edema and myofiber degeneration observed in the heart were also indicative of vascular leakage and its consequences. Conclusions Overall, these observations suggest that, in the rat, the lung is the main target organ for the S1P1 competitive antagonism-induced acute vascular leakage, which appears first as transient and asymptomatic but could lead, upon chronic dosing, to lung remodeling with functional impairments. Hence, this not only raises the question of organ specificity in the homeostasis of vascular barriers, but also provides insight into the pre-clinical evaluation of a potential safety window for S1P1 competitive antagonists as drug candidates. PMID:28005953

  12. Pseudogene BMI1P1 expression as a novel predictor for acute myeloid leukemia development and prognosis

    PubMed Central

    Zhou, Ling-Yu; Zhai, Ling-Ling; Yin, Jia-Yu; Vanessa, Minse Evola-Deniz; Zhou, Jiao; Zhang, Jing; Tang, Xi; Lin, Jiang; Qian, Jun; Deng, Zhao-Qun

    2016-01-01

    The BMI1P1 levels of 144 de novo AML patients and 36 healthy donors were detected by real-time quantitative PCR (RQ-PCR). BMI1P1 was significantly down-regulated in AML compared with control (P < 0.001). A receiver operating characteristic (ROC) curve revealed that BMI1P1 expression could differentiate patients with AML from control subjects (AUC = 0.895, 95% CI: 0.835–0.954, P < 0.001). The percentage of blasts in bone marrow (BM) was significantly lower in BMI1P1 high-expressed group versus low-expressed group (P = 0.008). BMI1P1 high-expressed cases had significantly higher complete remission (CR) than BMI1P1 low-expressed cases (P = 0.023). Furthermore, Kaplan–Meier demonstrated that both whole AML cohort and non-M3-AML patients with low BMI1P1 expression showed shorter leukemia free survival (LFS, P = 0.002 and P = 0.01, respectively) and overall survival (OS, P < 0.001 and P = 0.011, respectively) than those with high BMI1P1 expression. Multivariate analysis also showed that BMI1P1 over-expression was an independent favorable prognostic factor for OS in both whole and non-M3 cohort of AML patients (HR = 0.462, 95% CI = 0.243–0.879, P = 0.019 and HR = 0.483, 95% CI = 0.254–0.919, P = 0.027). To further investigate the significance of BMI1P1 expression in the follow-up of AML patients, we monitored the BMI1P1 level in 26 de novo AML patients and found that the BMI1P1 level increased significantly from the initial diagnosis to post-CR (P < 0.001). These results indicated that BMI1P1 might contribute to the diagnosis of AML and the assessment of therapeutic effect. PMID:27329719

  13. Investigating the molecular mechanisms through which FTY720-P causes persistent S1P1 receptor internalization

    PubMed Central

    Sykes, David A; Riddy, Darren M; Stamp, Craig; Bradley, Michelle E; McGuiness, Neil; Sattikar, Afrah; Guerini, Danilo; Rodrigues, Ines; Glaenzel, Albrecht; Dowling, Mark R; Mullershausen, Florian; Charlton, Steven J

    2014-01-01

    Background and Purpose The molecular mechanism underlying the clinical efficacy of FTY720-P is thought to involve persistent internalization and enhanced degradation of the S1P1 receptor subtype (S1P1R). We have investigated whether receptor binding kinetics and β-arrestin recruitment could play a role in the persistent internalization of the S1P1R by FTY720-P. Experimental Approach [3H]-FTY720-P and [33P]-S1P were used to label CHO-S1P1/3Rs for binding studies. Ligand efficacy was assessed through [35S]-GTPγS binding and β-arrestin recruitment. Metabolic stability was evaluated using a bioassay measuring intracellular Ca2+ release. CHO-S1P1/3R numbers were determined, following FTY720-P treatment using flow cytometry. Key Results The kinetic off-rate of [3H]-FTY720-P from the S1P1R was sixfold slower than from the S1P3R, and comparable to [33P]-S1P dissociation from S1P1/3Rs. S1P and FTY720-P stimulated [35S]-GTPγS incorporation to similar degrees, but FTY720-P was over 30-fold less potent at S1P3Rs. FTY720-P stimulated a higher level of β-arrestin recruitment at S1P1Rs, 132% of the total recruited by S1P. In contrast, FTY720-P was a weak partial agonist at S1P3R, stimulating just 29% of the total β-arrestin recruited by S1P. Internalization experiments confirmed that cell surface expression of the S1P1R but not the S1P3R was reduced following a pulse exposure to FTY720-P, which is metabolically stable unlike S1P. Conclusions and Implications FTY720-P and S1P activation of the S1P1R results in receptor internalization as a consequence of an efficient recruitment of β-arrestin. The combination of slow off-rate, efficacious β-arrestin recruitment and metabolic stability all contribute to FTY720-P's ability to promote prolonged S1P1R internalization and may be critical factors in its efficacy in the clinic. PMID:24641481

  14. Discovery of oxazole and triazole derivatives as potent and selective S1P(1) agonists through pharmacophore-guided design.

    PubMed

    Tian, Yulin; Jin, Jing; Wang, Xiaojian; Hu, Jinping; Xiao, Qiong; Zhou, Wanqi; Chen, Xiaoguang; Yin, Dali

    2014-10-06

    We have discovered a series of triazole/oxazole-containing 2-substituted 2-aminopropane-1,3-diol derivatives as potent and selective S1P1 agonists (prodrugs) based on pharmacophore-guided rational design. Most compounds showed high affinity and selectivity for S1P1 receptor. Compounds 19b, 19d and 19p displayed clear dose responsiveness in the lymphocyte reduction model when administered orally at doses of 0.3, 1.0, 3.0 mg/kg with reduced effect on heart rate. These three compounds were also identified to have favorable pharmacokinetic properties.

  15. Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways.

    PubMed

    Yoon, Chang Min; Hong, Bok Sil; Moon, Hyung Geun; Lim, Seyoung; Suh, Pann-Ghill; Kim, Yoon-Keun; Chae, Chi-Bom; Gho, Yong Song

    2008-08-15

    The lymphatic system plays pivotal roles in mediating tissue fluid homeostasis and immunity, and excessive lymphatic vessel formation is implicated in many pathological conditions, which include inflammation and tumor metastasis. However, the molecular mechanisms that regulate lymphatic vessel formation remain poorly characterized. Sphingosine-1-phosphate (S1P) is a potent bioactive lipid that is implicated in a variety of biologic processes such as inflammatory responses and angiogenesis. Here, we first report that S1P acts as a lymphangiogenic mediator. S1P induced migration, capillary-like tube formation, and intracellular Ca(2+) mobilization, but not proliferation, in human lymphatic endothelial cells (HLECs) in vitro. Moreover, a Matrigel plug assay demonstrated that S1P promoted the outgrowth of new lymphatic vessels in vivo. HLECs expressed S1P1 and S1P3, and both RNA interference-mediated down-regulation of S1P1 and an S1P1 antagonist significantly blocked S1P-mediated lymphangiogenesis. Furthermore, pertussis toxin, U73122, and BAPTA-AM efficiently blocked S1P-induced in vitro lymphangiogenesis and intracellular Ca(2+) mobilization of HLECs, indicating that S1P promotes lymphangiogenesis by stimulating S1P1/G(i)/phospholipase C/Ca(2+) signaling pathways. Our results suggest that S1P is the first lymphangiogenic bioactive lipid to be identified, and that S1P and its receptors might serve as new therapeutic targets against inflammatory diseases and lymphatic metastasis in tumors.

  16. Late-stage optimization of a tercyclic class of S1P3-sparing, S1P1 receptor agonists.

    PubMed

    Horan, Joshua C; Kuzmich, Daniel; Liu, Pingrong; DiSalvo, Darren; Lord, John; Mao, Can; Hopkins, Tamara D; Yu, Hui; Harcken, Christian; Betageri, Raj; Hill-Drzewi, Melissa; Patenaude, Lori; Patel, Monica; Fletcher, Kimberly; Terenzzio, Donna; Linehan, Brian; Xia, Heather; Patel, Mita; Studwell, Debbie; Miller, Craig; Hickey, Eugene; Levin, Jeremy I; Smith, Dustin; Kemper, Raymond A; Modis, Louise K; Bannen, Lynne C; Chan, Diva S; Mac, Morrison B; Ng, Stephanie; Wang, Yong; Xu, Wei; Lemieux, René M

    2016-01-15

    Poor solubility and cationic amphiphilic drug-likeness were liabilities identified for a lead series of S1P3-sparing, S1P1 agonists originally developed from a high-throughput screening campaign. This work describes the subsequent optimization of these leads by balancing potency, selectivity, solubility and overall molecular charge. Focused SAR studies revealed favorable structural modifications that, when combined, produced compounds with overall balanced profiles. The low brain exposure observed in rat suggests that these compounds would be best suited for the potential treatment of peripheral autoimmune disorders.

  17. QED contributions to the 3s-3p transitions in highly charged Na-like ions

    NASA Astrophysics Data System (ADS)

    Seely, J. F.; Wagner, R. A.

    1990-05-01

    The QED contributions to the energy intervals 3s1/2-3p1/2, 3p1/2-3p3/2, and 3s1/2-3p3/2 in highly charged Na-like ions were determined by comparing the transition energies derived from the observations with the relativistic many-body perturbation-theory calculations of Johnson, Blundell, and Sapirstein [Phys. Rev. A 38, 2699 (1988)] that do not include QED effects. The determined QED contributions differ considerably from the one-electron QED contributions and are in better agreement with screened-nucleus QED contributions. Predicted transition energies and wavelengths are presented for the Na-like ions with atomic numbers up to Z=92.

  18. Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease

    PubMed Central

    Karuppuchamy, Thangaraj; Behrens, En-hui; González-Cabrera, Pedro; Sarkisyan, Gor; Gima, Lauren; Boyer, Joshua D.; Bamias, Giorgos; Jedlicka, Paul; Veny, Marisol; Clark, David; Peach, Robert; Scott, Fiona; Rosen, Hugh; Rivera-Nieves, Jesús

    2016-01-01

    The sphingosine-1-phosphate receptor-1 (S1P1) agonist ozanimod ameliorates ulcerative colitis, yet its mechanism of action is unknown. Here we examine the cell subsets that express S1P1 in intestine using S1P1-eGFP mice, the regulation of S1P1 expression in lymphocytes after administration of DSS, after colitis induced by transfer of CD4+CD45RBhi cells and by crossing a mouse with TNF-driven ileitis with S1P1-eGFP mice. We then assayed the expression of enzymes that regulate intestinal S1P levels, and the effect of FTY720 on lymphocyte behavior and S1P1 expression. We found that not only T and B cells express S1P1, but also dendritic (DC) and endothelial cells. Furthermore, chronic but not acute inflammatory signals increased S1P1 expression, while the enzymes that control tissue S1P levels in mice and humans with IBD were uniformly dysregulated, favoring synthesis over degradation. Finally, we observed that FTY720 reduced T cell velocity and induced S1P1 degradation and retention of naïve but not effector T cells. Our data demonstrate that chronic inflammation modulates S1P1 expression and tissue S1P levels and suggests that the anti-inflammatory properties of S1PR agonists might not be solely due to their lymphopenic effects, but also due to potential effects on DC migration and vascular barrier function. PMID:27049060

  19. Three different up-titration regimens of ponesimod, an S1P1 receptor modulator, in healthy subjects.

    PubMed

    Scherz, Michael W; Brossard, Patrick; D'Ambrosio, Daniele; Ipek, Murat; Dingemanse, Jasper

    2015-06-01

    Ponesimod is a selective S1P1 receptor modulator, and induces dose-dependent reduction of circulating lymphocytes upon oral dosing. Previous studies showed that single doses up to 75 mg or multiple doses up to 40 mg once daily are well tolerated, and heart rate (HR) reduction and atrio-ventricular conduction delays upon treatment initiation are reduced by gradual up-titration to the maintenance dose. This single-center, open-label, randomized, multiple-dose, 3-treatment, 3-way crossover study compared the tolerability, safety, pharmacokinetics, cardiodynamics, and effects on lymphocytes of 3 different up-titration regimens of ponesimod in healthy male and female subjects. Up-titration regimens comprised escalating periods of b.i.d. dosing (2.5 or 5 mg) and q.d. dosing (10 or 20 mg or both). After the third up-titration period a variable-duration washout period of 1-3 days was followed by re-challenge with a single 20-mg dose of ponesimod. Adverse events were transient and mild to moderate in intensity, not different between regimens. HR decrease after the first dose was greater than after all subsequent doses, including up-titration doses. Little or no HR change was observed with morning doses of b.i.d. regimens, suggesting that 2.5 and 5 mg b.i.d. are sufficient to sustain cardiac desensitization for the 12-hours dosing interval.

  20. DNA looping-dependent autorepression of LEE1 P1 promoters by Ler in enteropathogenic Escherichia coli (EPEC)

    PubMed Central

    Bhat, Abhayprasad; Shin, Minsang; Jeong, Jae-Ho; Kim, Hyun-Ju; Lim, Hyung-Ju; Rhee, Joon Haeng; Paik, Soon-Young; Takeyasu, Kunio; Tobe, Toru; Yen, Hilo; Lee, Gwangrog; Choy, Hyon E.

    2014-01-01

    Ler, a homolog of H-NS in enteropathogenic Escherichia coli (EPEC), plays a critical role in the expression of virulence genes encoded by the pathogenic island, locus of enterocyte effacement (LEE). Although Ler acts as an antisilencer of multiple LEE operons by alleviating H-NS–mediated silencing, it represses its own expression from two LEE1 P1 promoters, P1A and P1B, that are separated by 10 bp. Various in vitro biochemical methods were used in this study to elucidate the mechanism underlying transcription repression by Ler. Ler acts through two AATT motifs, centered at position −111.5 on the coding strand and at +65.5 on the noncoding strand, by simultaneously repressing P1A and P1B through DNA-looping. DNA-looping was visualized using atomic force microscopy. It is intriguing that an antisilencing protein represses transcription, not by steric exclusion of RNA polymerase, but by DNA-looping. We propose that the DNA-looping prevents further processing of open promoter complex (RPO) at these promoters during transcription initiation. PMID:24920590

  1. Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling.

    PubMed

    Gatfield, John; Monnier, Lucile; Studer, Rolf; Bolli, Martin H; Steiner, Beat; Nayler, Oliver

    2014-07-01

    The sphingosine-1-phosphate (S1P) type 1 receptor (S1P1R) is a novel therapeutic target in lymphocyte-mediated autoimmune diseases. S1P1 receptor desensitization caused by synthetic S1P1 receptor agonists prevents T-lymphocyte egress from secondary lymphoid organs into the circulation. The selective S1P1 receptor agonist ponesimod, which is in development for the treatment of autoimmune diseases, efficiently reduces peripheral lymphocyte counts and displays efficacy in animal models of autoimmune disease. Using ponesimod and the natural ligand S1P, we investigated the molecular mechanisms leading to different signaling, desensitization and trafficking behavior of S1P1 receptors. In recombinant S1P1 receptor-expressing cells, ponesimod and S1P triggered Gαi protein-mediated signaling and β-arrestin recruitment with comparable potency and efficiency, but only ponesimod efficiently induced intracellular receptor accumulation. In human umbilical vein endothelial cells (HUVEC), ponesimod and S1P triggered translocation of the endogenous S1P1 receptor to the Golgi compartment. However, only ponesimod treatment caused efficient surface receptor depletion, receptor accumulation in the Golgi and degradation. Impedance measurements in HUVEC showed that ponesimod induced only short-lived Gαi protein-mediated signaling followed by resistance to further stimulation, whereas S1P induced sustained Gαi protein-mediated signaling without desensitization. Inhibition of S1P lyase activity in HUVEC rendered S1P an efficient S1P1 receptor internalizing compound and abrogated S1P-mediated sustained signaling. This suggests that S1P lyase - by facilitating S1P1 receptor recycling - is essential for S1P-mediated sustained signaling, and that synthetic agonists are functional antagonists because they are not S1P lyase substrates.

  2. Effects of multiple-dose ponesimod, a selective S1P1 receptor modulator, on lymphocyte subsets in healthy humans

    PubMed Central

    Jurcevic, Stipo; Juif, Pierre-Eric; Hamid, Colleen; Greenlaw, Roseanna; D’Ambrosio, Daniele; Dingemanse, Jasper

    2017-01-01

    This study investigated the effects of ponesimod, a selective S1P1 receptor modulator, on T lymphocyte subsets in 16 healthy subjects. Lymphocyte subset proportions and absolute numbers were determined at baseline and on Day 10, after once-daily administration of ponesimod (10 mg, 20 mg, and 40 mg each consecutively for 3 days) or placebo (ratio 3:1). The overall change from baseline in lymphocyte count was −1,292±340×106 cells/L and 275±486×106 cells/L in ponesimod- and placebo-treated subjects, respectively. This included a decrease in both T and B lymphocytes following ponesimod treatment. A decrease in naïve CD4+ T cells (CD45RA+CCR7+) from baseline was observed only after ponesimod treatment (−113±98×106 cells/L, placebo: 0±18×106 cells/L). The number of T-cytotoxic (CD3+CD8+) and T-helper (CD3+CD4+) cells was significantly altered following ponesimod treatment compared with placebo. Furthermore, ponesimod treatment resulted in marked decreases in CD4+ T-central memory (CD45RA−CCR7+) cells (−437±164×106 cells/L) and CD4+ T-effector memory (CD45RA−CCR7−) cells (−131±57×106 cells/L). In addition, ponesimod treatment led to a decrease of −228±90×106 cells/L of gut-homing T cells (CLA−integrin β7+). In contrast, when compared with placebo, CD8+ T-effector memory and natural killer (NK) cells were not significantly reduced following multiple-dose administration of ponesimod. In summary, ponesimod treatment led to a marked reduction in overall T and B cells. Further investigations revealed that the number of CD4+ cells was dramatically reduced, whereas CD8+ and NK cells were less affected, allowing the body to preserve critical viral-clearing functions. PMID:28096659

  3. CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs.

    PubMed

    Shiow, Lawrence R; Rosen, David B; Brdicková, Nadezda; Xu, Ying; An, Jinping; Lanier, Lewis L; Cyster, Jason G; Matloubian, Mehrdad

    2006-03-23

    Naive lymphocytes continually enter and exit lymphoid organs in a recirculation process that is essential for immune surveillance. During immune responses, the egress process can be shut down transiently. When this occurs locally it increases lymphocyte numbers in the responding lymphoid organ; when it occurs systemically it can lead to immunosuppression as a result of the depletion of recirculating lymphocytes. Several mediators of the innate immune system are known to cause shutdown, including interferon alpha/beta (IFN-alpha/beta) and tumour necrosis factor, but the mechanism has been unclear. Here we show that treatment with the IFN-alpha/beta inducer polyinosine polycytidylic acid (hereafter 'poly(I:C)') inhibited egress by a mechanism that was partly lymphocyte-intrinsic. The transmembrane C-type lectin CD69 was rapidly induced and CD69-/- cells were poorly retained in lymphoid tissues after treatment with poly(I:C) or infection with lymphocytic choriomeningitis virus. Lymphocyte egress requires sphingosine 1-phosphate receptor-1 (S1P1), and IFN-alpha/beta was found to inhibit lymphocyte responsiveness to S1P. By contrast, CD69-/- cells retained S1P1 function after exposure to IFN-alpha/beta. In coexpression experiments, CD69 inhibited S1P1 chemotactic function and led to downmodulation of S1P1. In a reporter assay, S1P1 crosslinking led to co-crosslinking and activation of a CD69-CD3zeta chimaera. CD69 co-immunoprecipitated with S1P1 but not the related receptor, S1P3. These observations indicate that CD69 forms a complex with and negatively regulates S1P1 and that it functions downstream of IFN-alpha/beta, and possibly other activating stimuli, to promote lymphocyte retention in lymphoid organs.

  4. Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like head-group interactions

    PubMed Central

    Gonzalez-Cabrera, Pedro J.; Jo, Euijung; Sanna, M. Germana; Brown, Steven; Leaf, Nora; Marsolais, David; Schaeffer, Marie-Therese; Chapman, Jacqueline; Cameron, Michael; Guerrero, Miguel; Roberts, Edward; Rosen, Hugh

    2008-01-01

    Strong evidence exists for interactions of zwitterionic phosphate and amine groups in Sphingosine-1 phosphate (S1P) to conserved R and E residues present at the extracellular face of transmembrane-3 (TM3) of S1P receptors. The contribution of R120 and E121 for high affinity ligand-receptor interactions is essential, as single-point R120A or E121A S1P1 mutants neither bind S1P nor transduce S1P function. Because S1P receptors are therapeutically interesting, identifying potent selective agonists with different binding modes and in vivo efficacy is of pharmacological importance. Here we describe a modestly water-soluble highly-selective S1P1 agonist (CYM-5442) that does not require R120 or E121 residues for activating S1P1-dependent p42/p44 MAPK phosphorylation, which defines a new hydrophobic pocket in S1P1. CYM-5442 is a full agonist in vitro for S1P1 internalization, phosphorylation and ubiquitination. Importantly, CYM-5442 was a full agonist for induction and maintenance of S1P1-dependent lymphopenia, decreasing B-lymphocytes by 65% and T-lymphocytes by 85% of vehicle. Induction of CYM-5442 lymphopenia was dose and time-dependent, requiring serum concentrations in the 50 nM range. In vitro measures of S1P1 activation by CYM-5442 were non-competitively inhibited by a specific S1P1 antagonist (W146), competitive for S1P, FTY720-P and SEW2871. In addition, lymphopenia by CYM-5442 was reversed by W146 administration or upon pharmacokinetic agonist clearance. Pharmacokinetics in mice also indicated that CYM-5442 partitions significantly in central nervous tissue. These data show that CYM-5442 activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo through a hydrophobic pocket, separable from the orthosteric site of S1P binding that is headgroup dependent. PMID:18708635

  5. Long intergenic non-coding RNA APOC1P1-3 inhibits apoptosis by decreasing α-tubulin acetylation in breast cancer

    PubMed Central

    Liao, X-H; Wang, J-G; Li, L-Y; Zhou, D-M; Ren, K-H; Jin, Y-T; Lv, L; Yu, J-G; Yang, J-Y; Lu, Q; Zou, Q; Yu, J; Liu, X-P; Zhou, P

    2016-01-01

    Increasing evidence indicates that long non-coding RNAs (lncRNAs) act as important regulatory factors in tumor progression. However, their roles in breast cancer remain largely unknown. In present studies, we identified aberrantly expressed long intergenic non-coding RNA APOC1P1-3 (lincRNA-APOC1P1-3) in breast cancer by microarray, verified it by quantitative real-time PCR, and assessed methylation status in the promoter region by pyrosequencing. We also investigated the biological functions with plasmid transfection and siRNA silencing experiments, and further explored their mechanisms by RNA pull-down and RNA immunoprecipitation to identify binding proteins. We found that 224 lncRNAs were upregulated in breast cancer, whereas 324 were downregulated. The lincRNA-APOC1P1-3 was overexpressed in breast cancer, which was related to tumor size and hypomethylation in its promoter region. We also found that APOC1P1-3 could directly bind to tubulin to decrease α-tubulin acetylation, to inactivate caspase-3, and to inhibit apoptosis. This study demonstrates that overexpression of APOC1P1-3 can inhibit breast cancer apoptosis. PMID:27228351

  6. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver

    PubMed Central

    Sun, Yue; Chen, Yutian; Swendeman, Steven L.; Jung, Bongnam; Chavez, Deebly; Cao, Zhongwei; Christoffersen, Christina; Nielsen, Lars Bo; Schwab, Susan R.; Rafii, Shahin; Hla, Timothy

    2016-01-01

    Regeneration of hepatic sinusoidal vasculature is essential for non-fibrotic liver regrowth and restoration of its metabolic capacity. However, little is known about how this specialized vascular niche is regenerated. Here we show that activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) by its natural ligand bound to HDL (HDL-S1P) induces liver regeneration and curtails fibrosis. In mice lacking HDL-S1P, liver regeneration after partial hepatectomy was impeded and associated with aberrant vascular remodeling, thrombosis and peri-sinusoidal fibrosis. Notably, this “maladaptive repair” phenotype was recapitulated in mice that lack S1P1 in the endothelium. Reciprocally, enhanced plasma levels of HDL-S1P or administration of SEW2871, a pharmacological agonist specific for S1P1 enhanced regeneration of metabolically functional vasculature and alleviated fibrosis in mouse chronic injury and cholestasis models. This study shows that natural and pharmacological ligands modulate endothelial S1P1 to stimulate liver regeneration and inhibit fibrosis, suggesting that activation of this pathway may be a novel therapeutic strategy for liver fibrosis. PMID:28018969

  7. Ponesimod, a selective S1P1 receptor modulator: a potential treatment for multiple sclerosis and other immune-mediated diseases

    PubMed Central

    D’Ambrosio, Daniele; Freedman, Mark S.; Prinz, Joerg

    2016-01-01

    The first oral treatment for relapsing multiple sclerosis, the nonselective sphingosine-1-phosphate receptor (S1PR) modulator fingolimod, led to identification of a pivotal role of sphingosine-1-phosphate and one of its five known receptors, S1P1R, in regulation of lymphocyte trafficking in multiple sclerosis. Modulation of S1P3R, initially thought to cause some of fingolimod’s side effects, prompted the search for novel compounds with high selectivity for S1P1R. Ponesimod is an orally active, selective S1P1R modulator that causes dose-dependent sequestration of lymphocytes in lymphoid organs. In contrast to the long half-life/slow elimination of fingolimod, ponesimod is eliminated within 1 week of discontinuation and its pharmacological effects are rapidly reversible. Clinical data in multiple sclerosis have shown a dose-dependent therapeutic effect of ponesimod and defined 20 mg as a daily dose with desired efficacy, and acceptable safety and tolerability. Phase II clinical data have also shown therapeutic efficacy of ponesimod in psoriasis. These findings have increased our understanding of psoriasis pathogenesis and suggest clinical utility of S1P1R modulation for treatment of various immune-mediated disorders. A gradual dose titration regimen was found to minimize the cardiac effects associated with initiation of ponesimod treatment. Selectivity for S1P1R, rapid onset and reversibility of pharmacological effects, and an optimized titration regimen differentiate ponesimod from fingolimod, and may lead to better safety and tolerability. Ponesimod is currently in phase III clinical development to assess efficacy and safety in relapsing multiple sclerosis. A phase II study is also ongoing to investigate the potential utility of ponesimod in chronic graft versus host disease. PMID:26770667

  8. Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.

    PubMed

    Singleton, Patrick A; Chatchavalvanich, Santipongse; Fu, Panfeng; Xing, Junjie; Birukova, Anna A; Fortune, Jennifer A; Klibanov, Alexander M; Garcia, Joe G N; Birukov, Konstantin G

    2009-04-24

    Endothelial cell (EC) barrier dysfunction results in increased vascular permeability, leading to increased mass transport across the vessel wall and leukocyte extravasation, the key mechanisms in pathogenesis of tissue inflammation and edema. We have previously demonstrated that OxPAPC (oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine) significantly enhances vascular endothelial barrier properties in vitro and in vivo and attenuates endothelial hyperpermeability induced by inflammatory and edemagenic agents via Rac and Cdc42 GTPase dependent mechanisms. These findings suggested potential important therapeutic value of barrier-protective oxidized phospholipids. In this study, we examined involvement of signaling complexes associated with caveolin-enriched microdomains (CEMs) in barrier-protective responses of human pulmonary ECs to OxPAPC. Immunoblotting from OxPAPC-treated ECs revealed OxPAPC-mediated rapid recruitment (5 minutes) to CEMs of the sphingosine 1-phosphate receptor (S1P(1)), the serine/threonine kinase Akt, and the Rac1 guanine nucleotide exchange factor Tiam1 and phosphorylation of caveolin-1, indicative of signaling activation in CEMs. Abolishing CEM formation (methyl-beta-cyclodextrin) blocked OxPAPC-mediated Rac1 activation, cytoskeletal reorganization, and EC barrier enhancement. Silencing (small interfering RNA) Akt expression blocked OxPAPC-mediated S1P(1) activation (threonine phosphorylation), whereas silencing S1P(1) receptor expression blocked OxPAPC-mediated Tiam1 recruitment to CEMs, Rac1 activation, and EC barrier enhancement. To confirm our in vitro results in an in vivo murine model of acute lung injury with pulmonary vascular hyperpermeability, we observed that selective lung silencing of caveolin-1 or S1P(1) receptor expression blocked OxPAPC-mediated protection from ventilator-induced lung injury. Taken together, these results suggest Akt-dependent transactivation of S1P(1) within CEMs is important for Ox

  9. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

    PubMed Central

    Choi, Ji Woong; Gardell, Shannon E.; Herr, Deron R.; Rivera, Richard; Lee, Chang-Wook; Noguchi, Kyoko; Teo, Siew Teng; Yung, Yun C.; Lu, Melissa; Kennedy, Grace; Chun, Jerold

    2011-01-01

    Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720 (fingolimod), recently approved as an oral treatment for relapsing forms of multiple sclerosis. Its mechanism of action is thought to be immunological through an active phosphorylated metabolite, FTY720-P, that resembles S1P and alters lymphocyte trafficking through receptor subtype S1P1. However, previously reported expression and in vitro studies of S1P receptors suggested that direct CNS effects of FTY720 might theoretically occur through receptor modulation on neurons and glia. To identify CNS cells functionally contributing to FTY720 activity, genetic approaches were combined with cellular and molecular analyses. These studies relied on the functional assessment, based on clinical score, of conditional null mouse mutants lacking S1P1 in CNS cell lineages and challenged by experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. All conditional null mutants displayed WT lymphocyte trafficking that responded normally to FTY720. In marked contrast, EAE was attenuated and FTY720 efficacy was lost in CNS mutants lacking S1P1 on GFAP-expressing astrocytes but not on neurons. In situ hybridization studies confirmed that astrocyte loss of S1P1 was the key alteration in functionally affected mutants. Reductions in EAE clinical scores were paralleled by reductions in demyelination, axonal loss, and astrogliosis. Receptor rescue and pharmacological experiments supported the loss of S1P1 on astrocytes through functional antagonism by FTY720-P as a primary FTY720 mechanism. These data identify nonimmunological CNS mechanisms of FTY720 efficacy and implicate S1P signaling pathways within the CNS as targets for multiple sclerosis therapies. PMID:21177428

  10. 3D-QSAR Studies on Thiazolidin-4-one S1P1 Receptor Agonists by CoMFA and CoMSIA

    PubMed Central

    Qian, Chuiwen; Zheng, Junxia; Xiao, Gaokeng; Guo, Jialiang; Yang, Zhaoqi; Huang, Li; Chao, Wei; Rao, Longyi; Sun, Pinghua

    2011-01-01

    Selective S1P1 receptor agonists have therapeutic potential to treat a variety of immune-mediated diseases. A series of 2-imino-thiazolidin-4-one derivatives displaying potent S1P1 receptor agonistic activity were selected to establish 3D-QSAR models using CoMFA and CoMSIA methods. Internal and external cross-validation techniques were investigated as well as some measures including region focusing, progressive scrambling, bootstraping and leave-group-out. The satisfactory CoMFA model predicted a q2 value of 0.751 and an r2 value of 0.973, indicating that electrostatic and steric properties play a significant role in potency. The best CoMSIA model, based on a combination of steric, electrostatic, hydrophobic and H-bond donor descriptors, predicted a q2 value of 0.739 and an r2 value of 0.923. The models were graphically interpreted using contour plots which gave more insight into the structural requirements for increasing the activity of a compound, providing a solid basis for future rational design of more active S1P1 receptor agonists. PMID:22072901

  11. Ligand-binding pocket shape differences between S1P1 and S1P3 determine efficiency of chemical probe identification by uHTS

    PubMed Central

    Schürer, Stephan C.; Brown, Steven J.; Cabrera, Pedro Gonzales; Schaeffer, Marie-Therese; Chapman, Jacqueline; Jo, Euijung; Chase, Peter; Spicer, Tim; Hodder, Peter; Rosen, Hugh

    2008-01-01

    We have studied the Sphingosine 1-phosphate (S1P) receptor system to better understand why certain molecular targets within a closely related family are much more tractable when identifying compelling chemical leads. Five medically important G protein-coupled receptors for S1P regulate heart rate, coronary artery caliber, endothelial barrier integrity, and lymphocyte trafficking. Selective S1P receptor agonist probes would be of great utility to study receptor subtype-specific function. Through systematic screening of the same libraries, we identified novel selective agonists chemotypes for each of the S1P1 and S1P3 receptors. uHTS for S1P1 was more effective than for S1P3, with many selective, low nanomolar hits of proven mechanism emerging for. Receptor structure modeling and ligand docking reveal differences between the receptor binding pockets, which are the basis for sub-type selectivity. Novel selective agonists interact primarily in the hydrophobic pocket of the receptor in the absence of head-group interactions. Chemistry-space and shape-based analysis of the screening libraries in combination with the binding models explain the observed differential hit rates and enhanced efficiency for lead discovery for S1P1 vs. S1P3 in this closely related receptor family. PMID:18590333

  12. Synthesis and evaluation of CS-2100, a potent, orally active and S1P(3)- sparing S1P(1) agonist.

    PubMed

    Nakamura, Tsuyoshi; Asano, Masayoshi; Sekiguchi, Yukiko; Mizuno, Yumiko; Tamaki, Kazuhiko; Nara, Futoshi; Kawase, Yumi; Yabe, Yoshiyuki; Nakai, Daisuke; Kamiyama, Emi; Urasaki-Kaneno, Yoko; Shimozato, Takaichi; Doi-Komuro, Hiromi; Kagari, Takashi; Tomisato, Wataru; Inoue, Ryotaku; Nagasaki, Miyuki; Yuita, Hiroshi; Oguchi-Oshima, Keiko; Kaneko, Reina; Nishi, Takahide

    2012-05-01

    Modulators of sphingosine phosphate receptor-1 (S1P(1)) have recently been focused as a suppressant of autoimmunity. We have discovered a 4-ethylthiophene-based S1P(1) agonist 1-({4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl}methyl)azetidine-3-carboxylic acid (CS-2100, 8) showing potent S1P(1) agonist activity against S1P(3) and an excellent in vivo potency. We report herein the synthesis of CS-2100 (8) and pharmacological effects such as S1P(1) and S1P(3) agonist activity in vitro, peripheral blood lymphocyte lowering effects and the suppressive effects on adjuvant-induced arthritis and experimental autoimmune encephalomyelitis (EAE) in animal models. The pharmacokinetic data were also reported. CS-2100 (8) had >5000-fold greater agonist activity for human S1P(1) (EC(50); 4.0 nM) relative to S1P(3) (EC(50); >20,000 nM). Following administration of single oral doses of 0.1 and 1 mg/kg of CS-2100 (8) in rats, lymphocyte counts decreased significantly, with a nadir at 8 and/or 12 h post-dose and recovery to vehicle control levels by 24-48 h post-dose. CS-2100 (8) is efficacious in the adjuvant-induced arthritis model in rats (ID(50); 0.44 mg/kg). In the EAE model compared to the vehicle-treated group, significant decreases in the cumulative EAE scores were observed for 0.3 and 1 mg/kg CS-2100 (8) groups in mice. While CS-2100 (8) showed potent efficacy in various animal disease models, it was also revealed that the central 1,2,4-oxadiazole ring of CS-2100 (8) was decomposed by enterobacteria in intestine of rats and monkeys, implicating the latent concern about an external susceptibility in its metabolic process in the upcoming clinical studies.

  13. State-selective preparation of A r2 + and K r2 + by resonantly enhanced two-photon double ionization via intermediate Rydberg states using high-order harmonics

    NASA Astrophysics Data System (ADS)

    Yamada, Kana; Iwasaki, Atsushi; Sato, Takahiro; Midorikawa, Katsumi; Yamanouchi, Kaoru

    2016-11-01

    Simultaneous two-electron emission processes of Ar induced by high-order harmonics of near-infrared femtosecond laser pulses were investigated by coincidence photoelectron spectroscopy. Two-photon double ionization processes via the 3 s 3 p6n p (n ˜25 ) intermediate resonances of Ar were observed, which selectively created the 3 s 3 p51P state of A r2 + . The similar double ionization processes were also observed in Kr. The selective creation indicates that the core electron configuration of the doubly ionized state tends to be the same as that of the intermediate state and that the emitted two electrons tend to form the singlet state.

  14. Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin.

    PubMed

    Singleton, Patrick A; Dudek, Steven M; Chiang, Eddie T; Garcia, Joe G N

    2005-10-01

    Endothelial cell (EC) barrier dysfunction results in increased vascular permeability observed in inflammation, tumor angiogenesis, and atherosclerosis. The platelet-derived phospholipid sphingosine-1-phosphate (S1P) decreases EC permeability in vitro and in vivo and thus has obvious therapeutic potential. We examined S1P-mediated human pulmonary artery EC signaling and barrier regulation in caveolin-enriched microdomains (CEM). Immunoblotting from S1P-treated EC revealed S1P-mediated rapid recruitment (1 microM, 5 min) to CEMs of the S1P receptors S1P1 and S1P3, p110 PI3 kinase alpha and beta catalytic subunits, the Rac1 GEF, Tiam1, and alpha-actinin isoforms 1 and 4. Immunoprecipitated p110 PI3 kinase catalytic subunits from S1P-treated EC exhibited PIP3 production in CEMs. Immunoprecipitation of S1P receptors from CEM fractions revealed complexes containing Tiam1 and S1P1. PI3 kinase inhibition (LY294002) attenuated S1P-induced Tiam1 association with S1P1, Tiam1/Rac1 activation, alpha-actinin-1/4 recruitment, and EC barrier enhancement. Silencing of either S1P1 or Tiam1 expression resulted in the loss of S1P-mediated Rac1 activation and alpha-actinin-1/4 recruitment to CEM. Finally, silencing S1P1, Tiam1, or both alpha-actinin isoforms 1/4 inhibits S1P-induced cortical F-actin rearrangement and S1P-mediated barrier enhancement. Taken together, these results suggest that S1P-induced recruitment of S1P1 to CEM fractions promotes PI3 kinase-mediated Tiam1/Rac1 activation required for alpha-actinin-1/4-regulated cortical actin rearrangement and EC barrier enhancement.

  15. Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells

    PubMed Central

    Igarashi, Junsuke; Hashimoto, Takeshi; Kubota, Yasuo; Shoji, Kazuyo; Maruyama, Tokumi; Sakakibara, Norikazu; Takuwa, Yoh; Ujihara, Yoshihiro; Katanosaka, Yuki; Mohri, Satoshi; Naruse, Keiji; Yamashita, Tetsuo; Okamoto, Ryuji; Hirano, Katsuya; Kosaka, Hiroaki; Takata, Maki; Konishi, Ryoji; Tsukamoto, Ikuko

    2014-01-01

    COA-Cl (2Cl-C.OXT-A) is a recently developed adenosine-like nucleic acid analog that promotes angiogenesis via the mitogen-activated protein (MAP) kinases ERK1/2. Endothelial S1P1 receptor plays indispensable roles in developmental angiogenesis. In this study, we examined the functions of S1P1 in COA-Cl-induced angiogenic responses. Antagonists for S1P1, W146, and VPC23019, substantially but still partly inhibited the effects of COA-Cl with regard to ERK1/2 activation and tube formation in cultured human umbilical vein endothelial cells (HUVEC). Antagonists for adenosine A1 receptor and purinergic P2Y1 receptor were without effect. Genetic knockdown of S1P1 with siRNA, but not that of S1P3, attenuated COA-Cl-elicited ERK1/2 responses. The signaling properties of COA-Cl showed significant similarities to those of sphingosine 1-phosphate, an endogenous S1P1 ligand, in that both induced responses sensitive to pertussis toxin (Gα i/o inhibitor), 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM), (calcium chelator), and PP2 (c-Src tyrosine kinase inhibitor). COA-Cl elevated intracellular Ca2+ concentration and induced tyrosine phosphorylation of p130Cas, a substrate of c-Src, in HUVEC. COA-Cl displaced [3H]S1P in a radioligand-binding competition assay in chem-1 cells overexpressing S1P1. However, COA-Cl activated ERK1/2 in CHO-K1 cells that lack functional S1P1 receptor, suggesting the presence of additional yet-to-be-defined COA-Cl target in these cells. The results thus suggest the major contribution of S1P1 in the angiogenic effects of COA-Cl. However, other mechanism such as that seen in CHO-K1 cells may also be partly involved. Collectively, these findings may lead to refinement of the design of this nucleic acid analog and ultimately to development of small molecule-based therapeutic angiogenesis. PMID:25505610

  16. Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.

    PubMed

    Harijith, Anantha; Pendyala, Srikanth; Ebenezer, David L; Ha, Alison W; Fu, Panfeng; Wang, Yue-Ting; Ma, Ke; Toth, Peter T; Berdyshev, Evgeny V; Kanteti, Prasad; Natarajan, Viswanathan

    2016-08-01

    Hyperoxia-induced lung injury adversely affects ICU patients and neonates on ventilator assisted breathing. The underlying culprit appears to be reactive oxygen species (ROS)-induced lung damage. The major contributor of hyperoxia-induced ROS is activation of the multiprotein enzyme complex NADPH oxidase. Sphingosine-1-phosphate (S1P) signaling is known to be involved in hyperoxia-mediated ROS generation; however, the mechanism(s) of S1P-induced NADPH oxidase activation is unclear. Here, we investigated various steps in the S1P signaling pathway mediating ROS production in response to hyperoxia in lung endothelium. Of the two closely related sphingosine kinases (SphKs)1 and 2, which synthesize S1P from sphingosine, only Sphk1(-/-) mice conferred protection against hyperoxia-induced lung injury. S1P is metabolized predominantly by S1P lyase and partial deletion of Sgpl1 (Sgpl1(+/-)) in mice accentuated lung injury. Hyperoxia stimulated S1P accumulation in human lung microvascular endothelial cells (HLMVECs), and downregulation of S1P transporter spinster homolog 2 (Spns2) or S1P receptors S1P1&2, but not S1P3, using specific siRNA attenuated hyperoxia-induced p47(phox) translocation to cell periphery and ROS generation in HLMVECs. These results suggest a role for Spns2 and S1P1&2 in hyperoxia-mediated ROS generation. In addition, p47(phox) (phox:phagocyte oxidase) activation and ROS generation was also reduced by PF543, a specific SphK1 inhibitor in HLMVECs. Our data indicate a novel role for Spns2 and S1P1&2 in the activation of p47(phox) and production of ROS involved in hyperoxia-mediated lung injury in neonatal and adult mice.

  17. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors.

    PubMed

    Wiltshire, Rachael; Nelson, Vicky; Kho, Dan Ting; Angel, Catherine E; O'Carroll, Simon J; Graham, E Scott

    2016-01-27

    Herein we show that S1P rapidly and acutely reduces the focal adhesion strength and barrier tightness of brain endothelial cells. xCELLigence biosensor technology was used to measure focal adhesion, which was reduced by S1P acutely and this response was mediated through both S1P1 and S1P2 receptors. S1P increased secretion of several pro-inflammatory mediators from brain endothelial cells. However, the magnitude of this response was small in comparison to that mediated by TNFα or IL-1β. Furthermore, S1P did not significantly increase cell-surface expression of any key cell adhesion molecules involved in leukocyte recruitment, included ICAM-1 and VCAM-1. Finally, we reveal that S1P acutely and dynamically regulates microvascular endothelial barrier tightness in a manner consistent with regulated rapid opening followed by closing and strengthening of the barrier. We hypothesise that the role of the S1P receptors in this process is not to cause barrier dysfunction, but is related to controlled opening of the endothelial junctions. This was revealed using real-time measurement of barrier integrity using ECIS ZΘ TEER technology and endothelial viability using xCELLigence technology. Finally, we show that these responses do not occur simply though the pharmacology of a single S1P receptor but involves coordinated action of S1P1 and S1P2 receptors.

  18. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors

    PubMed Central

    Wiltshire, Rachael; Nelson, Vicky; Kho, Dan Ting; Angel, Catherine E.; O’Carroll, Simon J.; Graham, E. Scott

    2016-01-01

    Herein we show that S1P rapidly and acutely reduces the focal adhesion strength and barrier tightness of brain endothelial cells. xCELLigence biosensor technology was used to measure focal adhesion, which was reduced by S1P acutely and this response was mediated through both S1P1 and S1P2 receptors. S1P increased secretion of several pro-inflammatory mediators from brain endothelial cells. However, the magnitude of this response was small in comparison to that mediated by TNFα or IL-1β. Furthermore, S1P did not significantly increase cell-surface expression of any key cell adhesion molecules involved in leukocyte recruitment, included ICAM-1 and VCAM-1. Finally, we reveal that S1P acutely and dynamically regulates microvascular endothelial barrier tightness in a manner consistent with regulated rapid opening followed by closing and strengthening of the barrier. We hypothesise that the role of the S1P receptors in this process is not to cause barrier dysfunction, but is related to controlled opening of the endothelial junctions. This was revealed using real-time measurement of barrier integrity using ECIS ZΘ TEER technology and endothelial viability using xCELLigence technology. Finally, we show that these responses do not occur simply though the pharmacology of a single S1P receptor but involves coordinated action of S1P1 and S1P2 receptors. PMID:26813587

  19. Laser gain on 3p-3d and 3s-3p transitions and X-ray line ratios for the nitrogen isoelectronic sequence

    NASA Technical Reports Server (NTRS)

    Feldman, U.; Seely, J. F.; Bhatia, A. K.

    1989-01-01

    Results are presented on calculations of the 72 levels belonging to the 2s(2)2p(3), 2s2p(4), 2p(5), 2s(2)2p(2)3s, 2s(2)2p(2)3p, and 2s(2)2p(2)3d configurations of the N I isoelectronic sequence for the ions Ar XII, Ti XVI, Fe XX, Zn XXIV, and Kr XXX, for electron densities up to 10 to the 24th/cu cm. It was found that large population inversions and gain occur between levels in the 2s(2)2p(2)3p configuration and levels in the 2s(2)2p(2)3d configuration that cannot decay to the ground configuration by an electric dipole transition. For increasing electron densities, the intensities of the X-ray transitions from the 2s(2)2p(2)3p configuration to the ground configuration decrease relative to the transitions from the 2s(2)2p(2)3s and 2s(2)2p(2)3d configurations to the ground configuration. The density dependence of these X-ray line ratios is presented.

  20. Vitamin D3 protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis.

    PubMed

    Pierucci, Federica; Garcia-Gil, Mercedes; Frati, Alessia; Bini, Francesca; Martinesi, Maria; Vannini, Eleonora; Mainardi, Marco; Luzzati, Federico; Peretto, Paolo; Caleo, Matteo; Meacci, Elisabetta

    2017-04-01

    Besides its classical function of bone metabolism regulation, 1alpha, 25-dihydroxyvitamin D3 (1,25(OH)2D3), acts on a variety of tissues including the nervous system, where the hormone plays an important role as neuroprotective, antiproliferating and differentiating agent. Sphingolipids are bioactive lipids that play critical and complex roles in regulating cell fate. In the present paper we have investigated whether sphingolipids are involved in the protective action of 1,25(OH)2D3. We have found that 1,25(OH)2D3 prevents amyloid-β peptide (Aβ(1-42)) cytotoxicity both in differentiated SH-SY5Y human neuroblastoma cells and in vivo. In differentiated SH-SY5Y cells, Aβ(1-42) strongly reduces the sphingosine-1-phosphate (S1P)/ceramide (Cer) ratio while 1,25(OH)2D3 partially reverts this effect. 1,25(OH)2D3 reverts also the Aβ(1-42)-induced reduction of sphingosine kinase activity. We have also studied the crosstalk between 1,25(OH)2D3 and S1P signaling pathways downstream to the activation of S1P receptor subtype S1P1. Notably, we found that 1,25(OH)2D3 prevents the reduction of S1P1 expression promoted by Aβ(1-42) and thereby it modulates the downstream signaling leading to ER stress damage (p38MAPK/ATF4). Similar effects were observed by using ZK191784. In addition, chronic treatment with 1,25(OH)2D3 protects from aggregated Aβ(1-42)-induced damage in the CA1 region of the rat hippocampus and promotes cell proliferation in the hippocampal dentate gyrus of adult mice. In conclusion, these results represent the first evidence of the role of 1,25(OH)2D3 and its structural analogue ZK191784 in counteracting the Aβ(1-42) peptide-induced toxicity through the modulation of S1P/S1P1/p38MAPK/ATF4 pathway in differentiated SH-SY5Y cells.

  1. Co-evolutionary dynamics of the bacteria Vibrio sp. CV1 and phages V1G, V1P1, and V1P2: implications for phage therapy.

    PubMed

    Barbosa, Camilo; Venail, Patrick; Holguin, Angela V; Vives, Martha J

    2013-11-01

    Bacterial infections are the second largest cause of mortality in shrimp hatcheries. Among them, bacteria from the genus Vibrio constitute a major threat. As the use of antibiotics may be ineffective and banned from the food sector, alternatives are required. Historically, phage therapy, which is the use of bacteriophages, is thought to be a promising option to fight against bacterial infections. However, as for antibiotics, resistance can be rapidly developed. Since the emergence of resistance is highly undesirable, a formal characterization of the dynamics of its acquisition is mandatory. Here, we explored the co-evolutionary dynamics of resistance between the bacteria Vibrio sp. CV1 and the phages V1G, V1P1, and V1P2. Single-phage treatments as well as a cocktail composed of the three phages were considered. We found that in the presence of a single phage, bacteria rapidly evolved resistance, and the phages decreased their infectivity, suggesting that monotherapy may be an inefficient treatment to fight against Vibrio infections in shrimp hatcheries. On the contrary, the use of a phage cocktail considerably delayed the evolution of resistance and sustained phage infectivity for periods in which shrimp larvae are most susceptible to bacterial infections, suggesting the simultaneous use of multiple phages as a serious strategy for the control of vibriosis. These findings are very promising in terms of their consequences to different industrial and medical scenarios where bacterial infections are present.

  2. Structural evolution and valence electron-state change during ultra thin silicon-oxide growth

    NASA Astrophysics Data System (ADS)

    Shimizu, A.; Abe, S.; Nakayama, H.; Nishino, T.; Iida, S.

    2000-06-01

    We have studied valence electron-state changes of Si during initial oxidation of Si(111) clean surface, HF-treated Si(001) and Si(111) surfaces by Auger valence electron spectroscopy (AVES). The results showed that the valence electron-state changes during initial oxidation were sensitively reflected in Si[2s,2p,V] (V=3s,3p) AVES spectra and that they depended on both initial surface treatment and surface orientation. The local valence electron-states, local density of states in other words, showed the characteristic-structure evolution depending on the initial surface treatment and surface orientation.

  3. Does Occupational Exposure to Solvents and Pesticides in Association with Glutathione S-Transferase A1, M1, P1, and T1 Polymorphisms Increase the Risk of Bladder Cancer? The Belgrade Case-Control Study

    PubMed Central

    Savic-Radojevic, Ana R.; Bulat, Petar V.; Pljesa-Ercegovac, Marija S.; Dragicevic, Dejan P.; Djukic, Tatjana I.; Simic, Tatjana P.; Pekmezovic, Tatjana D.

    2014-01-01

    Objective We investigated the role of the glutathione S-transferase A1, M1, P1 and T1 gene polymorphisms and potential effect modification by occupational exposure to different chemicals in Serbian bladder cancer male patients. Patients and Methods A hospital-based case-control study of bladder cancer in men comprised 143 histologically confirmed cases and 114 age-matched male controls. Deletion polymorphism of glutathione S-transferase M1 and T1 was identified by polymerase chain reaction method. Single nucleotide polymorphism of glutathione S-transferase A1 and P1 was identified by restriction fragment length polymorphism method. As a measure of effect size, odds ratio (OR) with corresponding 95% confidence interval (95%CI) was calculated. Results The glutathione S-transferase A1, T1 and P1 genotypes did not contribute independently toward the risk of bladder cancer, while the glutathione S-transferase M1-null genotype was overrepresented among cases (OR = 2.1, 95% CI = 1.1–4.2, p = 0.032). The most pronounced effect regarding occupational exposure to solvents and glutathione S-transferase genotype on bladder cancer risk was observed for the low activity glutathione S-transferase A1 genotype (OR = 9.2, 95% CI = 2.4–34.7, p = 0.001). The glutathione S-transferase M1-null genotype also enhanced the risk of bladder cancer among subjects exposed to solvents (OR = 6,5, 95% CI = 2.1–19.7, p = 0.001). The risk of bladder cancer development was 5.3–fold elevated among glutathione S-transferase T1-active patients exposed to solvents in comparison with glutathione S-transferase T1-active unexposed patients (95% CI = 1.9–15.1, p = 0.002). Moreover, men with glutathione S-transferase T1-active genotype exposed to pesticides exhibited 4.5 times higher risk in comparison with unexposed glutathione S-transferase T1-active subjects (95% CI = 0.9–22.5, p = 0.067). Conclusion Null or low-activity genotypes of the

  4. Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: high density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1.

    PubMed

    Wilkerson, Brent A; Grass, G Daniel; Wing, Shane B; Argraves, W Scott; Argraves, Kelley M

    2012-12-28

    Sphingosine 1-phosphate (S1P) is a blood-borne lysosphingolipid that acts to promote endothelial cell (EC) barrier function. In plasma, S1P is associated with both high density lipoproteins (HDL) and albumin, but it is not known whether the carriers impart different effects on S1P signaling. Here we establish that HDL-S1P sustains EC barrier longer than albumin-S1P. We showed that the sustained barrier effects of HDL-S1P are dependent on signaling by the S1P receptor, S1P1, and involve persistent activation of Akt and endothelial NOS (eNOS), as well as activity of the downstream NO target, soluble guanylate cyclase (sGC). Total S1P1 protein levels were found to be higher in response to HDL-S1P treatment as compared with albumin-S1P, and this effect was not associated with increased S1P1 mRNA or dependent on de novo protein synthesis. Several pieces of evidence indicate that long term EC barrier enhancement activity of HDL-S1P is due to specific effects on S1P1 trafficking. First, the rate of S1P1 degradation, which is proteasome-mediated, was slower in HDL-S1P-treated cells as compared with cells treated with albumin-S1P. Second, the long term barrier-promoting effects of HDL-S1P were abrogated by treatment with the recycling blocker, monensin. Finally, cell surface levels of S1P1 and levels of S1P1 in caveolin-enriched microdomains were higher after treatment with HDL-S1P as compared with albumin-S1P. Together, the findings reveal S1P carrier-specific effects on S1P1 and point to HDL as the physiological mediator of sustained S1P1-PI3K-Akt-eNOS-sGC-dependent EC barrier function.

  5. Rydberg and autoionizing triplet states in Helium up to the N = 5 threshold

    NASA Astrophysics Data System (ADS)

    Argenti, L.

    2008-11-01

    Energy levels of highly excited bound Rydberg states, the position and widths of autoionizing states, and oscillator strengths are calculated for He 3S, 3P e, 3P o, 3D e and 3D o symmetries up to the N = 5 He + excitation threshold. The calculations are performed with the K-matrix B-spline method with maximum orbital angular momentum ℓ max = 8. Reliable doubly excited-state parameters up to the n = 20 multiplet below each ionization threshold are presented. One thousand and six hundred newly identified bound and metastable states, seven times those available in literature, fill many gaps, reveal a dozen intruder states, and allow new speculations on propensity rules and radiative decays of triplet Rydberg states.

  6. The A6Sigma+ - X6Sigma+ Transition of CrH, Einstein Coefficients and an Improved Description of the A State

    NASA Technical Reports Server (NTRS)

    Bauschlicher, Charles W., Jr.; Ram, R. S.; Bernath, Peter F.; Parsons, C. G.; Galehouse, D.; Arnold, James O. (Technical Monitor)

    2001-01-01

    The spectrum of CrH has been reinvestigated in the 9000-15000/cm region using the Fourier transform spectrometer of the National Solar Observatory. The 1-0 and 1-1 bands of the A6Sigma+ - X6Sigma+ transition have been measured and improved spectroscopic constants have been determined. A value for the 2-0 band origin has been obtained from the band head using estimated spectroscopic constants. These data provide a set of much improved equilibrium vibrational and rotational constants for the A6Sigma+ state. An accurate description of the A-X transition has been obtained using a multi-reference configuration interaction approach. The inclusion of both scalar relativity and Cr 3s3p correlation are required to obtain a good description of both states. The ab initio computed Einstein coefficients and radiative lifetimes are reported.

  7. A genome-wide regulatory framework identifies maize Pericarp Color1 (P1) controlled genes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    P1 encodes an R2R3-MYB transcription factor responsible for the accumulation of insecticidal flavones in maize silks and red phlobaphene pigments in pericarps and other floral tissues. Using genome-wide expression analyses (RNA-Seq) in pericarps and silks of plants with contrasting P1 alleles combin...

  8. Angle-resolved photoemission extended fine structure: Multiple layers of emitters and multiple initial states

    SciTech Connect

    Huff, W.R.A.; Kellar, S.A.; Moler, E.J. |; Chen, Y.; Wu, H.; Shirley, D.A.; Hussain, Z.

    1995-08-01

    Recently, angle-resolved photoemission extended fine structure (ARPEFS) has been applied to experimental systems involving multiple layers of emitters and non-s core-level photoemission in an effort to broaden the utility of the technique. Most of the previous systems have been comprised of atomic or molecular overlayers adsorbed onto a single-crystal, metal surface and the photoemission data were taken from an s atomic core-level in the overlayer. For such a system, the acquired ARPEFS data is dominated by the p{sub o} final state wave backscattering from the substrate atoms and is well understood. In this study, we investigate ARPEFS as a surface-region structure determination technique when applied to experimental systems comprised of multiple layers of photoemitters and arbitrary initial state core-level photoemission. Understanding the data acquired from multiple layers of photoemitters is useful for studying multilayer interfaces, ''buried'' surfaces, and clean crystals in ultra- high vacuum. The ability to apply ARPEFS to arbitrary initial state core-level photoemission obviously opens up many systems to analysis. Efforts have been ongoing to understand such data in depth. We present clean Cu(111) 3s, 3p, and 3d core-level, normal photoemission data taken on a high resolution soft x-ray beamline 9.3.2 at the Advanced Light Source in Berkeley, California and clean Ni(111) 3p normal photoemission data taken at the National Synchrotron Light Source in Upton, New York, USA.

  9. Grothendieck's constant and local models for noisy entangled quantum states

    SciTech Connect

    Acin, Antonio; Gisin, Nicolas; Toner, Benjamin

    2006-06-15

    We relate the nonlocal properties of noisy entangled states to Grothendieck's constant, a mathematical constant appearing in Banach space theory. For two-qubit Werner states {rho}{sub p}{sup W}=p|{psi}{sup -}><{psi}{sup -}|+(1-p)1/4, we show that there is a local model for projective measurements if and only if p{<=}1/K{sub G}(3), where K{sub G}(3) is Grothendieck's constant of order 3. Known bounds on K{sub G}(3) prove the existence of this model at least for p < or approx. 0.66, quite close to the current region of Bell violation, p{approx}0.71. We generalize this result to arbitrary quantum states.

  10. Photoionization of Cl+ from the 3s23p4 3P2,1,0 and the 3s23p4 1D2,1S0 states in the energy range 19-28 eV

    NASA Astrophysics Data System (ADS)

    McLaughlin, Brendan M.

    2017-01-01

    Absolute photoionization cross-sections for the Cl+ ion in its ground and the metastable states, 3s23p4 3P2,1,0 and 3s23p4 1D2,1S0, were measured recently at the Advanced Light Source at Lawrence Berkeley National Laboratory using the merged beams photon-ion technique at a photon energy resolution of 15 meV in the energy range 19-28 eV. These measurements are compared with large-scale Dirac-Coulomb R-matrix calculations in the same energy range. Photoionization of this sulphur-like chlorine ion is characterized by multiple Rydberg series of auto-ionizing resonances superimposed on a direct photoionization continuum. A wealth of resonance features observed in the experimental spectra is spectroscopically assigned, and their resonance parameters are tabulated and compared with the recent measurements. Metastable fractions in the parent ion beam are determined from this study. Theoretical resonance energies and quantum defects of the prominent Rydberg series 3s23p3nd, identified in the spectra as 3p → nd transitions, are compared with the available measurements made on this element. Weaker Rydberg series 3s23p3ns, identified as 3p → ns transitions and window resonances 3s3p4(4P)np features, due to 3s → np transitions, are also found in the spectra.

  11. β decay of Si,4038 (Tz=+5 ,+6 ) to low-lying core excited states in odd-odd P,4038 isotopes

    NASA Astrophysics Data System (ADS)

    Tripathi, Vandana; Lubna, R. S.; Abromeit, B.; Crawford, H. L.; Liddick, S. N.; Utsuno, Y.; Bender, P. C.; Crider, B. P.; Dungan, R.; Fallon, P.; Kravvaris, K.; Larson, N.; Macchiavelli, A. O.; Otsuka, T.; Prokop, C. J.; Richard, A. L.; Shimizu, N.; Tabor, S. L.; Volya, A.; Yoshida, S.

    2017-02-01

    Low-lying excited states in P,4038 have been identified in the β decay of Tz=+5 ,+6 , Si,4038. Based on the allowed nature of the Gamow-Teller (GT) decay observed, these states are assigned spin and parity of 1+ and are core-excited 1p1h intruder states with a parity opposite to the ground state. The occurrence of intruder states at low energies highlights the importance of pairing and quadrupole correlation energies in lowering the intruder states despite the N =20 shell gap. Configuration interaction shell model calculations with the state-of-art SDPF-MU effective interaction were performed to understand the structure of these 1p1h states in the even-A phosphorus isotopes. States in 40P with N =25 were found to have very complex configurations involving all the f p orbitals leading to deformed states as seen in neutron-rich nuclei with N ≈28 . The calculated GT matrix elements for the β decay highlight the dominance of the decay of the core neutrons rather than the valence neutrons.

  12. Relativistic many-body calculations of lifetimes, rates, and line strengths of multipole transitions between 3l-1 4l' states in Ni-like ions

    SciTech Connect

    Safronova, U I; Safronova, A S; Beiersdorfer, P

    2007-10-08

    Transition rates and line strengths are calculated for electric-multipole (E2 and E3) and magnetic-multipole (M1, M2, and M3) transitions between 3s{sup 2}3p{sup 6}3d{sup 10}, 3s{sup 2}3p{sup 6}3d{sup 9}4l, 3s{sup 2}3p{sup 5}3d{sup 10}4l, and 3s3p{sup 6}3d{sup 10}4l states (with 4l = 4s, 4p, 4d, and 4f) in Ni-like ions with the nuclear charges ranging from Z = 34 to 100. Relativistic many-body perturbation theory (RMBPT), including the Breit interaction, is used to evaluate retarded multipole matrix elements. Transition energies used in the calculation of line strengths and transition rates are from second-order RMBPT. Lifetimes of the 3s{sup 2}3p{sup 6}3d{sup 9}4s levels are given for Z = 34-100. Taking into account that calculations were performed in a very broad range of Z, most of the data are presented in graphs as Z-dependencies. The full set of data is given only for Ni-like W ion. In addition, we also give complete results for the 3d4s{sup 3}D{sub 2}-3d4s {sup 3}D{sub 1} magnetic-dipole transition, as the transition may be observed in future experiments, which measure both transition energies and radiative rates. These atomic data are important in the modeling of radiation spectra from Ni-like multiply-charged ions generated in electron beam ion trap experiments as well as for laboratory plasma diagnostics including fusion research.

  13. State Profiles.

    ERIC Educational Resources Information Center

    State-Federal Information Clearinghouse for Exceptional Children, Reston, VA.

    State-by-state public policy profiles are provided by the Council for Exceptional Children's State-Federal Information Clearinghouse. These profiles summarize the present legal base for the delivery of educational services to handicapped children in the United States. Included in each profile is information from various avenues used to establish…

  14. Heteroatom effects in XC5H5C Arduengo-type carbenes (X = CH, N, P, and As) in singlet and triplet states

    NASA Astrophysics Data System (ADS)

    Vessally, Esmail; Poorheravi, Mohammad Reza; Edjlali, Ladan; Motallebzadeh, Maryam

    2014-07-01

    Internal energy difference, Δ E s-t; enthalpy difference, Δ H s-t; Gibbs free energy difference, Δ G s-t, between the singlet (s) and triplet states (t) of XC5H5C, 1X (X = CH, N, P, and As) were computed at B3LYP/6-311++G** and MP2/6-311++G**//B3LYP/6-311++G** levels of theory. The Δ G s-t between the singlet and triplet states of 1 X were changed in the order: 1 P > 1 As > 1 N .

  15. State of the States 2014

    ERIC Educational Resources Information Center

    Journal of Education Finance, 2015

    2015-01-01

    Presenters at the State of the States Roundtable session at the 2014 National Education Finance Conference in Louisville were invited to submit their papers for publication. These papers address the following topics: (1) State issues affecting P-12 and/or higher education funding; (2) Funding priorities/trends for P-12 and/or higher education; (3)…

  16. State of the States 2013

    ERIC Educational Resources Information Center

    Journal of Education Finance, 2014

    2014-01-01

    Presenters at the State of the States Roundtable session at the 2014 National Education Finance Conference in Louisville were invited to submit their papers for publication. These papers address the following topics: (1) State issues affecting P-12 and/or higher education funding; (2) Funding priorities/trends for P-12 and/or higher education; (3)…

  17. The anticoagulant activated protein C (aPC) promotes metaplasticity in the hippocampus through an EPCR-PAR1-S1P1 receptors dependent mechanism.

    PubMed

    Maggio, Nicola; Itsekson, Zeev; Ikenberg, Benno; Strehl, Andreas; Vlachos, Andreas; Blatt, Ilan; Tanne, David; Chapman, Joab

    2014-08-01

    Thrombin and other clotting factors regulate long-term potentiation (LTP) in the hippocampus through the activation of the protease activated receptor 1 (PAR1) and consequent potentiation of N-methyl-d-aspartate receptor (NMDAR) functions. We have recently shown that the activation of PAR1 either by thrombin or the anticoagulant factor activated protein C (aPC) has differential effects on LTP. While thrombin activation of PAR1 induces an NMDAR-mediated slow onset LTP, which saturates the ability to induce further LTP in the exposed network, aPC stimulation of PAR1 enhances tetanus induced LTP through a voltage-gated calcium channels mediated mechanism. In this study, we addressed the mechanisms by which aPC enhances LTP in hippocampal slices. Using extracellular recordings, we show that a short tetanic stimulation, which does not induce LTP, is able to enhance plasticity in the presence of aPC through a mechanism that requires the activation of sphingosine-1 phosphate receptor 1 and intracellular Ca(2+) stores. These data identify aPC as a "metaplastic molecule", capable of shifting the threshold of LTP towards further potentiation. Our findings propose novel strategies to enhance plasticity in neurological diseases associated with the breakdown of the blood brain barrier and alterations in synaptic plasticity.

  18. SNPs of GSTM1, T1, P1, epoxide hydrolase and DNA repair enzyme XRCC1 and risk of urinary transitional cell carcinoma in southwestern Taiwan

    SciTech Connect

    Hsu, L.-I; Chiu, Allen W.; Huan, Steven K.; Chen, C.-L.; Wang, Y.-H.; Hsieh, F.-I; Chou, W.-L.; Wang, L.-H.; Chen, C.-J.

    2008-04-15

    A hospital-based case-control study was conducted near a former black-foot disease (BFD)-endemic area in southwestern Taiwan to examine the possible risk factors and genetic susceptibility for urinary transitional cell carcinoma (TCC). A total of 221 patients with pathologically confirmed TCC and 223 age-sex-matched control subjects from urology outpatient clinics were recruited between 1998 and 2002. The results showed that residency in the BFD area and consumption of well water for more than 10 years was a strong factor on urinary cancer risk (odds ratio [OR],8.16, 95% confidence interval [CI],3.34-19.90, p < 0.0001). Dose response relationship between average arsenic concentration in well water and TCC risk was also observed. Cigarette smoking played a relatively minor role in urinary carcinogenesis in this study. The GSTP1 Ile105Val A {yields} G polymorphism was significantly associated with cancer risk (A/G + G/G: OR = 0.60, 95%CI = 0.39-0.94, p = 0.02), and the effect of Val105 allele was largely confined to the subjects diagnosed earlier than 55 years old (A/G + G/G: OR,0.29; 95% CI, 0.09-0.87, p = 0.03). The results suggest that GSTP1 is a candidate for susceptibility locus and Ile105 allele may predispose individuals to early-onset urinary TCC. The GSTM1 null genotype was associated with tumors of high-invasiveness (OR,2.21; 95% CI, 1.34-4.73) as well as with early-onset TCC risk (OR,2.53; 95% CI, 0.97-6.59). Our preliminary results showed the XRCC1 Arg194Trp were associated with arsenic-related urinary TCC and the interaction between the genotype and the exposure was statistically significant. The modulating effect of the GSTM1, GSTT1, GSTP1 Ile105Val, EPHX Tyr113His and XRCC1 Arg280His on arsenic-related TCC risk was also suggestive. These observations implied that impaired metabolism of carcinogenic exposure as well as impaired DNA repair function play an important role in arsenic-related urinary transitional cell carcinogenesis.

  19. Shell model study of T =0 states for 96Cd by the nucleon-pair approximation

    NASA Astrophysics Data System (ADS)

    Fu, G. J.; Cheng, Y. Y.; Zhao, Y. M.; Arima, A.

    2016-08-01

    In this paper we study the nucleon-pair approximation for T =0 states of 96Cd in the 1 p1 /21 p3 /20 f5 /20 g9 /2 shell with the JUN45 interaction. The lowest seniority scheme and the isoscalar spin-one pair approximation are not enough to describe the states. The isoscalar spin-aligned pair approximation is reasonably good for the yrast 2+, 4+, 6+, 12+, 14+, and 16+ states as pointed out previously. Not only the yrast positive-parity states but also nonyrast states and negative-parity states are well described by both the isovector pair approximation and the isoscalar pair approximation. We calculate overlaps between nucleon-pair basis states and shell-model wave functions. The largest overlaps and the corresponding nucleon-pair basis states are presented. We find that isovector spin-zero pairs, isovector spin-two pairs, and isoscalar spin-aligned pairs are the dominant building blocks in these states.

  20. Practitioner States.

    ERIC Educational Resources Information Center

    1996

    This document contains four papers presented at a symposium on practitioner states moderated by Kay Bull at the 1996 conference of the Academy of Human Resource Development (AHRD). "The Effect of Locus of Control and Performance-Contingent Incentives on Productivity and Job Satisfaction in Self-Managing Teams" (Bonnie E. Garson, Douglas…

  1. State Treasure

    ERIC Educational Resources Information Center

    Olson, Cathy Applefeld

    2013-01-01

    When a music teacher is named Teacher of the Year for an entire state, one just know a special story awaits. The narrative of Heidi Welch, director of music at Hillsboro-Deering High School in New Hampshire, does not disappoint. Welch, who grew up in abject poverty and was often homeless, developed her love of music through memorizing and singing…

  2. State of the States 2016: Arts Education State Policy Summary

    ERIC Educational Resources Information Center

    Aragon, Stephanie

    2016-01-01

    The "State of the States 2016" summarizes state policies for arts education identified in statute or administrative code for all 50 states and the District of Columbia. Information is based on a comprehensive search of state education statute and codes on each state's relevant websites. Complete results from this review are available in…

  3. State of the States, 2012: Arts Education State Policy Summary

    ERIC Educational Resources Information Center

    Arts Education Partnership (NJ1), 2012

    2012-01-01

    The "State of the States 2012" summarizes state policies for arts education identified in statute or code for all 50 states and the District of Columbia. Information is based primarily on results from the AEP Arts Education State Policy Survey conducted in 2010-11, and updated in April 2012.

  4. Polarization measurements and high-spin states in 8638Sr48

    NASA Astrophysics Data System (ADS)

    Kumar, Naveen; Kumar, Suresh; Kumar, V.; Mandal, S. K.; Palit, R.; Saha, S.; Sethi, J.; Trivedi, T.; Pancholi, S. C.; Srivastava, P. C.

    2016-11-01

    The high-spin states in 86Sr nucleus were populated using the 76Ge(13C, 3n) reaction at a beam energy of 45 MeV. The γ-γ and γ-γ-γ coincidence measurements were used to establish the level scheme up to 10.9 MeV excitation energy and spin Iπ =19+. In our preliminary results reported earlier, a positive-parity dipole (ΔI = 1) band based on the 6878-keV level having M1 γ-ray transitions was identified. In the present work, the γ-rays and their sequence have been established for this band. The band may have a magnetic rotational character. The spin-parity of the levels were assigned by measuring the Directional Correlations of the Oriented (DCO) nuclei and the polarization asymmetry. The polarization measurements were performed for the first time for the γ-ray transitions in this nucleus. The experimental band structures were compared with the shell-model calculations using two recent effective interactions, JUN45 and jj44b in the 1p3/2, 0f5/2, 1p1/2, 0g9/2 model space. From the Tilted-Axis Cranking (TAC) calculations, the 4-qp π(g9/2) 2 ⊗ ν(g9/2) - 2 configuration is suggested for the lower-part of the (ΔI = 1) band up to spin Iπ =16+ and the 6-qp π [(g9/2) 2(f5/2) 1(p1/2) 1 ] ⊗ ν(g9/2) - 2 configuration for the upper-part of the band.

  5. Photoabsorption of the ground state of Ne and of Ne-like Na+, Mg2+, Al3+, Si4+, P5+, S6+, and Cl7+ ions

    NASA Astrophysics Data System (ADS)

    Sakho, I.

    2016-03-01

    Photoabsorption of the 1s2 2s2 2p6 (1S0) ground state of Ne-like ions is presented in this paper. Resonance energies and width of the 2 s 2p6 n p1P1 series of Ne and Ne-like Na+, Mg2+, Al3+, Si4+, P5+, S6+, and Cl7+ ions are reported. Wavelengths of the 2s2 2p6 (1S0) → 2s2 2p5(2P 3 / 2 , 1 / 2) n d transitions in neon-like Na+ ion and of the 2s2 2p6(1S0) → 2 s 2p6 n p1P1 transitions in Ne and in Ne-like Na+, Mg2+, Al3+, Si4+, P5+, S6+, and Cl7+ ions are tabulated. Analysis of the resonances investigated is done in the framework of the LS, jj and JK coupling schemes. All the calculations are made using the Screening constant by unit nuclear charge (SCUNC) formalism. Very good agreement is found between the SCUNC results and various experimental and theoretical literature values and new data for the Ne-like Si4+, P5+, S6+, and Cl7+ ions are listed.

  6. State of the States in Developmental Disabilities

    ERIC Educational Resources Information Center

    Braddock, David; Hemp, Richard; Rizzolo, Mary Kay

    2008-01-01

    This is the latest edition of the "State of the States in Developmental Disabilities" study--a thorough and the only one of its kind investigation on public spending, revenues, and programmatic trends of intellectual and developmental programs and services within the United States since 1977. Directed by leading researcher, Dr. David…

  7. United States Department of State Strategic Plan

    DTIC Science & Technology

    1998-01-01

    targets for worldwide reduction or elimination of the cultiva- tion, production, and commercial-scale import of cocaine, opium, heroin, mari- juana ...international sanctions against state sponsors of terrorism and urges their strict enforcement. State presses state spon- sors to abandon their support for

  8. Stats of the States

    MedlinePlus

    ... rates for fatal drug poisonings. Death Rates from Firearm Injuries: United States, 2013 - The latest state-based age-adjusted death rates for firearm-related fatalities. Death Rates from Homicide: United States, ...

  9. State Emergency Response Commissions

    EPA Pesticide Factsheets

    The Governor of each state has designated a State Emergency Response Commission (SERC) that is responsible for implementing the Emergency Planning and Community Right-to-Know Act (EPCRA) provisions within its state.

  10. Absolutely classical spin states

    NASA Astrophysics Data System (ADS)

    Bohnet-Waldraff, F.; Giraud, O.; Braun, D.

    2017-01-01

    We introduce the concept of "absolutely classical" spin states, in analogy to absolutely separable states of bipartite quantum systems. Absolutely classical states are states that remain classical (i.e., a convex sum of projectors on coherent states of a spin j ) under any unitary transformation applied to them. We investigate the maximal size of the ball of absolutely classical states centered on the maximally mixed state and derive a lower bound for its radius as a function of the total spin quantum number. We also obtain a numerical estimate of this maximal radius and compare it to the case of absolutely separable states.

  11. The Pennsylvania State University

    ERIC Educational Resources Information Center

    Burlingame, Philip J.; Dowhower, Andrea L.

    2009-01-01

    Founded in 1855 as the Farmer's High School, the Pennsylvania State University (Penn State) began as a small college in Centre County providing agricultural education to young men from regional farm families. Penn State became a land-grant university in 1863 following passage of the Morrill Act. Today, Penn State enrolls more than 83,000 students…

  12. Amorphization-induced strong localization of electronic states in CsPbBr3 and CsPbCl3 studied by optical absorption measurements

    NASA Astrophysics Data System (ADS)

    Kondo, S.; Sakai, T.; Tanaka, H.; Saito, T.

    1998-11-01

    Optical absorption spectra of amorphous CsPbX3 films (X=Br,Cl) are characterized by two Gaussian bands near the fundamental edge, with the optical energy gap largely blueshifted and the absorption intensity strongly reduced as compared with the crystalline films. The peak energies of the bands are close to those of the A and C bands of Pb-doped alkali halides. The spectral features are discussed in terms of a molecular orbital theory based on a quasicomplex Pb2+(X-)6 model similar to the complex model for the doped alkali halides. It is shown that not only Pb2+ 6s and 6p extended states near the band edges but also X- p states contributing to upper valence bands are localized by amorphization. The transitions from the localized Pb2+ 6s to 6p states produce the spin-orbit allowed 3P1 and dipole allowed 1P1 states responsible for the two Gaussians. The localized X- p states lie deeper in energy than the localized Pb2+ 6s state and only contribute to higher-energy absorption above the Gaussian bands, giving the reason for the reduced absorption near the fundamental edge. The blueshift of the optical energy gap is attributed to the disappearance of k dispersions for these one-electron states.

  13. Product-State Approximations to Quantum States

    NASA Astrophysics Data System (ADS)

    Brandão, Fernando G. S. L.; Harrow, Aram W.

    2016-02-01

    We show that for any many-body quantum state there exists an unentangled quantum state such that most of the two-body reduced density matrices are close to those of the original state. This is a statement about the monogamy of entanglement, which cannot be shared without limit in the same way as classical correlation. Our main application is to Hamiltonians that are sums of two-body terms. For such Hamiltonians we show that there exist product states with energy that is close to the ground-state energy whenever the interaction graph of the Hamiltonian has high degree. This proves the validity of mean-field theory and gives an explicitly bounded approximation error. If we allow states that are entangled within small clusters of systems but product across clusters then good approximations exist when the Hamiltonian satisfies one or more of the following properties: (1) high degree, (2) small expansion, or (3) a ground state where the blocks in the partition have sublinear entanglement. Previously this was known only in the case of small expansion or in the regime where the entanglement was close to zero. Our approximations allow an extensive error in energy, which is the scale considered by the quantum PCP (probabilistically checkable proof) and NLTS (no low-energy trivial-state) conjectures. Thus our results put restrictions on the possible Hamiltonians that could be used for a possible proof of the qPCP or NLTS conjectures. By contrast the classical PCP constructions are often based on constraint graphs with high degree. Likewise we show that the parallel repetition that is possible with classical constraint satisfaction problems cannot also be possible for quantum Hamiltonians, unless qPCP is false. The main technical tool behind our results is a collection of new classical and quantum de Finetti theorems which do not make any symmetry assumptions on the underlying states.

  14. State Analysis Database Tool

    NASA Technical Reports Server (NTRS)

    Rasmussen, Robert; Bennett, Matthew

    2006-01-01

    The State Analysis Database Tool software establishes a productive environment for collaboration among software and system engineers engaged in the development of complex interacting systems. The tool embodies State Analysis, a model-based system engineering methodology founded on a state-based control architecture (see figure). A state represents a momentary condition of an evolving system, and a model may describe how a state evolves and is affected by other states. The State Analysis methodology is a process for capturing system and software requirements in the form of explicit models and states, and defining goal-based operational plans consistent with the models. Requirements, models, and operational concerns have traditionally been documented in a variety of system engineering artifacts that address different aspects of a mission s lifecycle. In State Analysis, requirements, models, and operations information are State Analysis artifacts that are consistent and stored in a State Analysis Database. The tool includes a back-end database, a multi-platform front-end client, and Web-based administrative functions. The tool is structured to prompt an engineer to follow the State Analysis methodology, to encourage state discovery and model description, and to make software requirements and operations plans consistent with model descriptions.

  15. State-Chart Autocoder

    NASA Technical Reports Server (NTRS)

    Clark, Kenneth; Watney, Garth; Murray, Alexander; Benowitz, Edward

    2007-01-01

    A computer program translates Unified Modeling Language (UML) representations of state charts into source code in the C, C++, and Python computing languages. ( State charts signifies graphical descriptions of states and state transitions of a spacecraft or other complex system.) The UML representations constituting the input to this program are generated by using a UML-compliant graphical design program to draw the state charts. The generated source code is consistent with the "quantum programming" approach, which is so named because it involves discrete states and state transitions that have features in common with states and state transitions in quantum mechanics. Quantum programming enables efficient implementation of state charts, suitable for real-time embedded flight software. In addition to source code, the autocoder program generates a graphical-user-interface (GUI) program that, in turn, generates a display of state transitions in response to events triggered by the user. The GUI program is wrapped around, and can be used to exercise the state-chart behavior of, the generated source code. Once the expected state-chart behavior is confirmed, the generated source code can be augmented with a software interface to the rest of the software with which the source code is required to interact.

  16. Comparative State Politics.

    ERIC Educational Resources Information Center

    Brooks, Gary H.

    1981-01-01

    Describes a college course dealing with comparative state politics. Students learn about the way in which political scientists employ the study of American state politics as a "laboratory" for the development of scientific explanations of political phenomena. (RM)

  17. State Goals Overview

    EPA Pesticide Factsheets

    This presentation includes information on Best System of Emission Reduction (BSER), state flexibility and compliance options, examples of how to determine and calculate goals, on-the-way reductions, and a walk through of state goal derivation.

  18. Coma / Vegetative State

    MedlinePlus

    ... Vegetative State Legal Issues Sleeping Problems Anxiety & Stress Concussion / Mild TBI Living with Traumatic Brain Injury Speech & ... Conscious States After Severe Brain Injury Brain Trauma, Concussion, and Coma What Is the Glasgow Coma Scale? ...

  19. Malaria Treatment (United States)

    MedlinePlus

    ... Malaria Branch clinician. malaria@cdc.gov Malaria Treatment (United States) Recommend on Facebook Tweet Share Compartir Treatment of Malaria: Guidelines For Clinicians (United States) Download PDF version of Parts 1-3 formatted ...

  20. States of Matter

    NASA Video Gallery

    NASA scientists and engineers utilize the basic principles of the states of matter on a daily basis. The states and properties of matter are very important to the design and construction of NASA sp...

  1. 7 CFR 1220.615 - State and United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false State and United States. 1220.615 Section 1220.615... CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.615 State and United States. State and United States include the 50 States of the United States of America, the District of...

  2. Model State Efforts.

    ERIC Educational Resources Information Center

    Morgan, Gwen

    Models of state involvement in training child care providers are briefly discussed and the employers' role in training is explored. Six criteria for states that are taken as models are identified, and four are described. Various state activities are described for each criterion. It is noted that little is known about employer and other private…

  3. State Standards and Evolution

    ERIC Educational Resources Information Center

    Moore, Randy

    2004-01-01

    Throughout the United States various individuals and groups have tried to subvert science education by removing or weakening the treatment of evolution in state science-education standards. Most states' science-education standards support the teaching of evolution, but many in the general public and some policymakers want science classrooms to…

  4. One State, Two State, Red State, Blue State: Education Funding Accounts for Outcome Differences

    ERIC Educational Resources Information Center

    Meece, Darrell

    2008-01-01

    Using publically available data, states coded as "blue" based upon results from the 2004 presidential election were significantly higher in education funding than were states coded as "red." Students in blue states scored significantly higher on outcome measures of math and reading in grades four and eight in 2004 and 2007 than did students in red…

  5. Changing State Digital Libraries

    ERIC Educational Resources Information Center

    Pappas, Marjorie L.

    2006-01-01

    Research has shown that state virtual or digital libraries are evolving into websites that are loaded with free resources, subscription databases, and instructional tools. In this article, the author explores these evolving libraries based on the following questions: (1) How user-friendly are the state digital libraries?; (2) How do state digital…

  6. [California State Archives.

    ERIC Educational Resources Information Center

    Rea, Jay W.

    The first paper on the California State Archives treats the administrative status, legal basis of the archives program, and organization of the archives program. The problem areas in this States' archival program are discussed at length. The second paper gives a crude sketch of the legal and administrative history of the California State Archives,…

  7. Oxidation state in chondrites

    NASA Technical Reports Server (NTRS)

    Rubin, Alan E.; Fegley, Bruce; Brett, Robin

    1988-01-01

    An evaluation is made of extant data on chondrite oxidation states and intrinsic O fugacities. A variety of oxidation states are exhibited by the chondritic meteorites; petrologic and chemical data may be used to arrange the major chondrite groups in order of oxidation state. The intrinsic O fugacity measurements on chondrite whole-rock samples are noted to display a corresponding ordering of oxidation states. Metamorphosed chondrites and igneous meteorites that were substantially altered by metamorphic reactions, outgassing, and igneous processes may preserve information on the oxidation state and size of their parent bodies.

  8. Tripartite quantum state sharing.

    PubMed

    Lance, Andrew M; Symul, Thomas; Bowen, Warwick P; Sanders, Barry C; Lam, Ping Koy

    2004-04-30

    We demonstrate a multipartite protocol to securely distribute and reconstruct a quantum state. A secret quantum state is encoded into a tripartite entangled state and distributed to three players. By collaborating, any two of the three players can reconstruct the state, while individual players obtain nothing. We characterize this (2,3) threshold quantum state sharing scheme in terms of fidelity, signal transfer, and reconstruction noise. We demonstrate a fidelity averaged over all reconstruction permutations of 0.73+/-0.04, a level achievable only using quantum resources.

  9. State Technologies Advancement Collaborative

    SciTech Connect

    David S. Terry

    2012-01-30

    The U. S. Department of Energy (DOE), National Association of State Energy Officials (NASEO), and Association of State Energy Research and Technology Transfer Institutions (ASERTTI) signed an intergovernmental agreement on November 14, 2002, that allowed states and territories and the Federal Government to better collaborate on energy research, development, demonstration and deployment (RDD&D) projects. The agreement established the State Technologies Advancement Collaborative (STAC) which allowed the states and DOE to move RDD&D forward using an innovative competitive project selection and funding process. A cooperative agreement between DOE and NASEO served as the contracting instrument for this innovative federal-state partnership obligating funds from DOE's Office of Energy Efficiency and Renewable Energy and Office of Fossil Energy to plan, fund, and implement RDD&D projects that were consistent with the common priorities of the states and DOE. DOE's Golden Field Office provided Federal oversight and guidance for the STAC cooperative agreement. The STAC program was built on the foundation of prior Federal-State efforts to collaborate on and engage in joint planning for RDD&D. Although STAC builds on existing, successful programs, it is important to note that it was not intended to replace other successful joint DOE/State initiatives such as the State Energy Program or EERE Special Projects. Overall the STAC process was used to fund, through three competitive solicitations, 35 successful multi-state research, development, deployment, and demonstration projects with an overall average non-federal cost share of 43%. Twenty-two states were awarded at least one prime contract, and organizations in all 50 states and some territories were involved as subcontractors in at least one STAC project. Projects were funded in seven program areas: (1) Building Technologies, (2) Industrial Technologies, (3) Transportation Technologies, (4) Distributed Energy Resources, (5

  10. The State of State Science Standards, 2005

    ERIC Educational Resources Information Center

    Gross, Paul R.

    2005-01-01

    Until now, the No Child Left Behind Act of 2001 (NCLB) has focused everyone's attention on reading and math--and on whether schools are making "adequate yearly progress" in those two core subjects. Although some states incorporate additional subjects into their own accountability systems, reading and math have dominated most discussions of state…

  11. The State of State Science Standards, 2012

    ERIC Educational Resources Information Center

    Lerner, Lawrence S.; Goodenough, Ursula; Lynch, John; Schwartz, Martha; Schwartz, Richard

    2012-01-01

    This report examines K-12 science standards for fifty states and the District of Columbia, as well as the science assessment framework of the National Assessment of Educational Progress (NAEP). The reviewers' aim is to evaluate them for their intrinsic clarity, completeness, and scientific correctness. Their earlier evaluations, as well as those…

  12. Quantum State Engineering Via Coherent-State Superpositions

    NASA Technical Reports Server (NTRS)

    Janszky, Jozsef; Adam, P.; Szabo, S.; Domokos, P.

    1996-01-01

    The quantum interference between the two parts of the optical Schrodinger-cat state makes possible to construct a wide class of quantum states via discrete superpositions of coherent states. Even a small number of coherent states can approximate the given quantum states at a high accuracy when the distance between the coherent states is optimized, e. g. nearly perfect Fock state can be constructed by discrete superpositions of n + 1 coherent states lying in the vicinity of the vacuum state.

  13. Quantum State Smoothing

    NASA Astrophysics Data System (ADS)

    Guevara, Ivonne; Wiseman, Howard

    2015-10-01

    Smoothing is an estimation method whereby a classical state (probability distribution for classical variables) at a given time is conditioned on all-time (both earlier and later) observations. Here we define a smoothed quantum state for a partially monitored open quantum system, conditioned on an all-time monitoring-derived record. We calculate the smoothed distribution for a hypothetical unobserved record which, when added to the real record, would complete the monitoring, yielding a pure-state "quantum trajectory." Averaging the pure state over this smoothed distribution yields the (mixed) smoothed quantum state. We study how the choice of actual unraveling affects the purity increase over that of the conventional (filtered) state conditioned only on the past record.

  14. Quantum State Smoothing.

    PubMed

    Guevara, Ivonne; Wiseman, Howard

    2015-10-30

    Smoothing is an estimation method whereby a classical state (probability distribution for classical variables) at a given time is conditioned on all-time (both earlier and later) observations. Here we define a smoothed quantum state for a partially monitored open quantum system, conditioned on an all-time monitoring-derived record. We calculate the smoothed distribution for a hypothetical unobserved record which, when added to the real record, would complete the monitoring, yielding a pure-state "quantum trajectory." Averaging the pure state over this smoothed distribution yields the (mixed) smoothed quantum state. We study how the choice of actual unraveling affects the purity increase over that of the conventional (filtered) state conditioned only on the past record.

  15. New squeezed landau states

    NASA Technical Reports Server (NTRS)

    Aragone, C.

    1993-01-01

    We introduce a new set of squeezed states through the coupled two-mode squeezed operator. It is shown that their behavior is simpler than the correlated coherent states introduced by Dodonov, Kurmyshev, and Man'ko in order to quantum mechanically describe the Landau system, i.e., a planar charged particle in a uniform magnetic field. We compare results for both sets of squeezed states.

  16. State summaries: Indiana

    USGS Publications Warehouse

    Shaffer, K.R.

    2006-01-01

    In 2005, the Indiana industrial minerals industry generated $789 million, a record high for the state and an increase of 2.2% from 2004. Among all states, Indiana ranked 24th. Mineral commodities produced in the state included crushed limestone and dolomite, construction sand and gravel, industrial sand, dimension limestone, dimension sandstone, gypsum, common clay and shale, freshwater pearls, peat, lime, and masonry and portland cement.

  17. Cluster State Quantum Computation

    DTIC Science & Technology

    2014-02-01

    nearest neighbor cluster state has been shown to be a universal resource for MBQC thus we can say our quantum computer is universal. We note that...CLUSTER STATE QUANTUM COMPUTATION FEBRUARY 2014 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED STINFO COPY AIR FORCE...TITLE AND SUBTITLE CLUSTER STATE QUANTUM COMPUTATION 5a. CONTRACT NUMBER IN-HOUSE 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62788F 6

  18. State Demolition Information

    EPA Pesticide Factsheets

    Contact information and guidances for each state and selected territories's environmental agencies and programs relevant to large-scale residential demolition including asbestos, lead, and open burning.

  19. Optimally Squeezed Spin States

    NASA Astrophysics Data System (ADS)

    Rojo, Alberto

    2004-03-01

    We consider optimally spin-squeezed states that maximize the sensitivity of the Ramsey spectroscopy, and for which the signal to noise ratio scales as the number of particles N. Using the variational principle we prove that these states are eigensolutions of the Hamiltonian H(λ)=λ S_z^2-S_x, and that, for large N, the states become equivalent to the quadrature squeezed states of the harmonic oscillator. We present numerical results that illustrate the validity of the equivalence. We also present results of spin squeezing via atom-field interactions within the context of the Tavis-Cummings model. An ensemble of N two-level atoms interacts with a quantized cavity field. For all the atoms initially in their ground states, it is shown that spin squeezing of both the atoms and the field can be achieved provided the initial state of the cavity field has coherence between number states differing by 2. Most of the discussion is restricted to the case of a cavity field initially in a coherent state, but initial squeezed states for the field are also discussed. An analytic solution is found that is valid in the limit that the number of atoms is much greater than unity. References: A. G. Rojo, Phys. Rev A, 68, 013807 (2003); Claudiu Genes, P. R. Berman, and A. G. Rojo Phys. Rev. A 68, 043809 (2003).

  20. State initiatives in state-Federal relations

    SciTech Connect

    Standish, T.K.

    1980-05-01

    Based upon historical analysis, this paper examines the proper role of regulation at the state, regional, and federal levels of government. Four areas of inquiry are highlighted by the so-called crises in public utility industries. The first question is whether there should be a shift from passive to active regulation. Second, is increased regulatory power needed at regional and Federal levels of government in order to achieve an appropriate balance between state, regional, and Federal government, or does overcentralization breed economic inefficiency and autocratic decisions. Third, should regulators have a higher degree of power and control over private-utility companies to accomplish objectives mandated by state legislatures and Congress, or is the real problem that private incentives have not been given enough leeway to solve the problems that confront us. And, fourth, if we are to address today's opportunities, should planning efficiency and public interest norms displace the time-honored competitive-market standards of economic efficiency and social justice as the basis for regulatory decisions. At the root of these issues, there is a clash between those arguing for the use of a planning paradigm to solve economic problems and those advocating reliance upon market forces. Economic imperatives lead us to expect a continuation of a trend which resolves the market/nonmarket balance in favor of more government participation. Hence, the scope of state initiatives and the range of opportunities for policy action, will in fact, be defined by economic forces larger than the current debate on the issues. 8 references.

  1. Iowa State Fair.

    ERIC Educational Resources Information Center

    Ohrn, Deborah Gore, Ed.

    1994-01-01

    This issue of the "Goldfinch" focuses on the Iowa state fair. The magazine begins with a map of the fair as it looks today. The article explains that the first Iowa state fair was held in 1854. After traveling from town to town for several years, the fair settled in the capital city of Des Moines in 1878. Eight years later, in 1886, the…

  2. Healthcare. State Report

    ERIC Educational Resources Information Center

    Carnevale, Anthony P.; Smith, Nicole; Gulish, Artem; Beach, Bennett H.

    2012-01-01

    This report projects education requirements linked to forecasted job growth in healthcare by state and the District of Columbia from 2010 through 2020. It complements a larger national report which projects educational demand for healthcare for the same time period. The national report shows that with or without Obamacare, the United States will…

  3. Solid-state configurations

    NASA Technical Reports Server (NTRS)

    Schroeder, K. G.

    1980-01-01

    Two prototype solid-state phased array systems concepts developed for the solar power satellite (SPS) are described. In both concepts, the beam was centered on the rectenna by means of phase conjugation of a pilot signal emanating from the ground. Also discussed are results of solid state studies.

  4. Solid State Division

    SciTech Connect

    Green, P.H.; Watson, D.M.

    1989-08-01

    This report contains brief discussions on work done in the Solid State Division of Oak Ridge National Laboratory. The topics covered are: Theoretical Solid State Physics; Neutron scattering; Physical properties of materials; The synthesis and characterization of materials; Ion beam and laser processing; and Structure of solids and surfaces. (LSP)

  5. Chiropractic. New York State.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Office of the Professions.

    A reference guide to laws, rules, and regulations that govern the chiropractic practice in New York State is presented. After an overview of professional regulation in the state, licensing requirements/procedures for chiropractors are described. Provisions of Title VIII, Articles 130 and 132, of the Education Law are also covered, along with…

  6. State summaries: California

    USGS Publications Warehouse

    Kohl, S. G.

    2006-01-01

    According to the United States Geological Survey (USGS), California ranked second behind Arizona among the states in nonfuel mineral production during 2005. It accounted for 7% of the US's total. The market value of mineral production for California amounted to $3.7 billion. During the year, California produced 30 varieties of industrial minerals. The nonfuel minerals came from 820 active mines.

  7. Getting State Legislation Enacted

    ERIC Educational Resources Information Center

    Ochs, Mike

    2005-01-01

    One of the most important tasks an organization can take on is assisting in getting a law passed at the state level. Many times, passing a state law can be a critical first step to passing federal legislation on the same topic. Completing the various steps to bring a law to Congress can take anywhere from five to ten years, or even longer. Because…

  8. States of Consciousness

    PubMed Central

    Bell, Carl C.

    1980-01-01

    The art of psychiatry offers many different viewpoints from which to catalog behavior and thinking styles and, therefore, many physicians tend to have difficulty in conceptualizing features of behavioral medicine. A classification of states of consciousness with clinical examples of such states is presented to aid in a more clear understanding of human behavior. PMID:7365821

  9. Education and Fragile States

    ERIC Educational Resources Information Center

    Kirk, Jackie

    2007-01-01

    Within the fragile states agendas and policies of development agencies and organisations education is of concern; education is a social service sector in which the impacts of state fragility are significant, in terms of access and quality of provision for children, working conditions and support for teachers, good governance and legitimacy for the…

  10. State alternative route designations

    SciTech Connect

    Not Available

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a ``state routing agency,`` defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective.

  11. State alternative route designations

    SciTech Connect

    Not Available

    1989-07-01

    Pursuant to the Hazardous Materials Transportation Act (HMTA), the Department of Transportation (DOT) has promulgated a comprehensive set of regulations regarding the highway transportation of high-level radioactive materials. These regulations, under HM-164 and HM-164A, establish interstate highways as the preferred routes for the transportation of radioactive materials within and through the states. The regulations also provide a methodology by which a state may select alternative routes. First,the state must establish a state routing agency,'' defined as an entity authorized to use the state legal process to impose routing requirements on carriers of radioactive material (49 CFR 171.8). Once identified, the state routing agency must select routes in accordance with Large Quantity Shipments of Radioactive Materials or an equivalent routing analysis. Adjoining states and localities should be consulted on the impact of proposed alternative routes as a prerequisite of final route selection. Lastly, the states must provide written notice of DOT of any alternative route designation before the routes are deemed effective.

  12. Centennial State Libraries, 1998.

    ERIC Educational Resources Information Center

    Parent, Kathleen D., Ed.

    1998-01-01

    This document consists of 12 consecutive issues of the monthly "Centennial State Libraries" newsletter, of the Colorado Department of Education, State Library and Adult Education Office. The issues cover the year 1998. Each issue of the newsletter--except the August issue which is an Annual Report--includes some or all of the following…

  13. Grid State Estimation Tool

    SciTech Connect

    2014-10-09

    This software code is designed to track generator state variables in real time using the Ensemble Kalman Filter method with the aid of PMU measurements. This code can also be used to calibrate dynamic model parameters by augmenting parameters in the state variable vector.

  14. State Court Organization, 1980.

    ERIC Educational Resources Information Center

    National Center for State Courts, Williamsburg, VA.

    Information on state court organization as of January 1, 1980, in the 50 states, American Samoa, the District of Columbia, Guam, Puerto Rico, and the Virgin Islands is provided. Data were collected from published sources and through questionnaires. There are two major parts. Part I consists of 36 tables containing comparative data from all the…

  15. State and local governments

    NASA Technical Reports Server (NTRS)

    Barnes, Dennis

    1990-01-01

    The Virginia Space Grant Consortium approach to a close working relation to state and local governments is presented as a model for consideration. State government relations are especially important in that this is a primary resource in securing matching funds. Avenues for establishing these relationships are listed and discussed.

  16. Slippery Wenzel State.

    PubMed

    Dai, Xianming; Stogin, Birgitt Boschitsch; Yang, Shikuan; Wong, Tak-Sing

    2015-09-22

    Enhancing the mobility of liquid droplets on rough surfaces is of great interest in industry, with applications ranging from condensation heat transfer to water harvesting to the prevention of icing and frosting. The mobility of a liquid droplet on a rough solid surface has long been associated with its wetting state. When liquid drops are sitting on the top of the solid textures and air is trapped underneath, they are in the Cassie state. When the drops impregnate the solid textures, they are in the Wenzel state. While the Cassie state has long been associated with high droplet mobility and the Wenzel state with droplet pinning, our work challenges this existing convention by showing that both Cassie and Wenzel state droplets can be highly mobile on nanotexture-enabled slippery rough surfaces. Our surfaces were developed by engineering hierachical nano- and microscale textures and infusing liquid lubricant into the nanotextures alone to create a highly slippery rough surface. We have shown that droplet mobility can be maintained even after the Cassie-to-Wenzel transition. Moreover, the discovery of the slippery Wenzel state allows us to assess the fundamental limits of the classical and recent Wenzel models at the highest experimental precision to date, which could not be achieved by any other conventional rough surface. Our results show that the classical Wenzel eq (1936) cannot predict the wetting behaviors of highly wetting liquids in the Wenzel state.

  17. States Address Achievement Gaps.

    ERIC Educational Resources Information Center

    Christie, Kathy

    2002-01-01

    Summarizes 2 state initiatives to address the achievement gap: North Carolina's report by the Advisory Commission on Raising Achievement and Closing Gaps, containing an 11-point strategy, and Kentucky's legislation putting in place 10 specific processes. The North Carolina report is available at www.dpi.state.nc.us.closingthegap; Kentucky's…

  18. Cooperation Among State Agencies

    ERIC Educational Resources Information Center

    Wattenbarger, James L.; Hansen, Dean M.

    1975-01-01

    Most states have separate agencies to deal with vocational education, adult education, and community colleges. Because current procedures for interagency cooperation are inadequate and often nonproductive, there is a need for a national or extra-state catalyst to encourage cooperation in a positive way. Five strategies for cooperation are…

  19. Church and State.

    ERIC Educational Resources Information Center

    National Forum: Phi Kappa Phi Journal, 1988

    1988-01-01

    Church and state is discussed in four articles: "Recent Threats to Religious Liberty" (Dean M. Kelley, pp.16-22); "Municipal Church-State Litigation and the Issue of Standing" (Kenneth S. Saladin, pp. 23-25); "Prayer in Public Schools: The Court's Decisions" (Leo Pfeffer, pp. 26-29); and "Religion and Public…

  20. {2,6-Bis[(2,6-diisopropyl-phosphan-yl)-oxy]-4-fluoro-phenyl-κ(3)P,C(1),P'}(1H-pyrazole-κN(2))nickel(II) hexa-fluoro-phosphate.

    PubMed

    Kwan, Man-Lung; Conry, Sara J; Carfagna, Charles S; Press, Loren P; Ozerov, Oleg V; Hoffman, Norris W; Sykora, Richard E

    2012-10-01

    The title compound, [Ni(C(18)H(30)FO(2)P(2))(C(3)H(4)N(2))]PF(6), was prepared by halide abstraction with TlPF(6) in the presence of CH(3)CN in CDCl(3) from the respective neutral pincer chlorido analogue followed by addition of pyrazole. The PO-C-OP pincer ligand acts in typical trans-P(2) tridentate fashion to generate a distorted square-planar nickel structure. The Ni-N(pyrazole) distance is 1.925 (2) Å and the plane of the pyrazole ligand is rotated 56.2 (1)° relative to the approximate square plane surrounding the Ni(II) center in which the pyrazole is bound to the Ni(II) atom through its sp(2)-hybridized N atom. This Ni-N distance is similar to bond lengths in the other reported Ni(II) pincer-ligand square-planar pyrazole complex structures; however, its dihedral angle is significantly larger than any of those for the latter set of pyrazole complexes.

  1. Quantum State Magnification

    NASA Astrophysics Data System (ADS)

    Engelsen, Nils; Hosten, Onur; Krishnakumar, Rajiv; Kasevich, Mark

    2016-05-01

    The standard quantum limit (SQL) for quantum metrology has been surpassed by as much as a factor of 100 using entangled states. However, in order to utilize these states, highly engineered, low-noise state readout is required. Here we present a new method to bypass this requirement in a wide variety of physical systems. We implement the protocol experimentally in a system using the clock states of 5 ×105 87 Rb atoms. Through a nonlinear, optical cavity-mediated interaction we generate spin squeezed states. A small microwave rotation followed by an additional optical cavity interaction stage allow us to exploit the full sensitivity of the squeezed states with a fluorescence detection system. Though the technical noise floor of our fluorescence detection is 15dB above the SQL, we show metrology at 8dB below the SQL. This is the first time squeezed states prepared in a cavity are read out by fluorescence imaging. The method described can be used in any system with a suitable nonlinear interaction.

  2. Variational Transition State Theory

    SciTech Connect

    Truhlar, Donald G.

    2016-09-29

    This is the final report on a project involving the development and applications of variational transition state theory. This project involved the development of variational transition state theory for gas-phase reactions, including optimized multidimensional tunneling contributions and the application of this theory to gas-phase reactions with a special emphasis on developing reaction rate theory in directions that are important for applications to combustion. The development of variational transition state theory with optimized multidimensional tunneling as a useful computational tool for combustion kinetics involved eight objectives.

  3. Bipartite Composite Fermion States

    NASA Astrophysics Data System (ADS)

    Sreejith, G. J.; Tőke, C.; Wójs, A.; Jain, J. K.

    2011-08-01

    We study a class of ansatz wave functions in which composite fermions form two correlated “partitions.” These “bipartite” composite fermion states are demonstrated to be very accurate for electrons in a strong magnetic field interacting via a short-range 3-body interaction potential over a broad range of filling factors. Furthermore, this approach gives accurate approximations for the exact Coulomb ground state at 2+3/5 and 2+4/7 and is thus a promising candidate for the observed fractional quantum Hall states at the hole conjugate fractions at 2+2/5 and 2+3/7.

  4. Bipartite composite fermion States.

    PubMed

    Sreejith, G J; Toke, C; Wójs, A; Jain, J K

    2011-08-19

    We study a class of ansatz wave functions in which composite fermions form two correlated "partitions." These "bipartite" composite fermion states are demonstrated to be very accurate for electrons in a strong magnetic field interacting via a short-range 3-body interaction potential over a broad range of filling factors. Furthermore, this approach gives accurate approximations for the exact Coulomb ground state at 2+3/5 and 2+4/7 and is thus a promising candidate for the observed fractional quantum Hall states at the hole conjugate fractions at 2+2/5 and 2+3/7.

  5. State summaries: Kentucky

    USGS Publications Warehouse

    Greb, S.F.; Anderson, W.H.

    2006-01-01

    Kentucky mines coal, limestone, clay, sand and gravel. Coal mining operations are carried out mainly in the Western Kentucky Coal Field and the Eastern Kentucky Coal field. As to nonfuel minerals, Mississippian limestones are mined in the Mississippian Plateaus Region and along Pine Mountain in southeastern Kentucky. Ordovician and Silurian limestones are mined from the central part of the state. Clay minerals that are mined in the state include common clay, ceramic and ball clays, refractory clay and shale. Just like in 2004, mining activities in the state remain significant.

  6. USGS Alaska State Mosaic

    USGS Publications Warehouse

    ,

    2008-01-01

    The Alaska State Mosaic consists of portions of scenes from the Multi-Resolution Land Characteristics 2001 (MRLC 2001) collection. The 172 selected scenes have been geometrically and radiometrically aligned to produce a seamless, relatively cloud-free image of the State. The scenes were acquired between July 1999 and September 2002, resampled to 120-meter pixels, and cropped to the State boundary. They were reprojected into a standard Alaska Albers projection with the U.S. National Elevation Dataset (NED) used to correct for relief.

  7. Study on the 8He ground state via 8He(p, d)7He and 8He(p, t)6He reaction at 82.3 MeV/nucleon

    NASA Astrophysics Data System (ADS)

    Lou, J. L.; Ye, Y. L.; Pang, D. Y.; Cao, Z. X.; Jiang, D. X.

    2013-03-01

    The differential cross sections for reactions 8He(p, d)7Heg.s and 8He(p, t)6He2+ were measured by the coincidence of d + 6 He and t + 4He in a wide angular range from 15 to 130 degree in the center-of-mass system. The cross sections of the 8He(p, t)6Heg.s reaction were extremely lower than that of 8He(p, t)6He2+ reaction, and was not obtained from the present data. The experimental results were compared to the preliminary theoretical calculations in the frame of adiabatic distorted-wave approximation with the code Fresco. The results show that the configuration of (1p3/2)2(1p1/2)2 may have some probability in the ground state wave function of 8He. The cluster structure of 8He = 5H + 3H could not be neglected.

  8. The Organic Solid State.

    ERIC Educational Resources Information Center

    Cowan, Dwaine O.; Wlygul, Frank M.

    1986-01-01

    Reviews interesting and useful electrical, magnetic, and optical properties of the organic solid state. Offers speculation as to areas of fruitful research. Discusses organic superconductors, conducting organic polymers, organic metals, and traces recent history of creation of organic metals. (JM)

  9. State Air Quality Standards.

    ERIC Educational Resources Information Center

    Pollution Engineering, 1978

    1978-01-01

    This article presents in tabular form the air quality standards for sulfur dioxide, carbon monoxide, nitrogen dioxide, photochemicals, non-methane hydrocarbons and particulates for each of the 50 states and the District of Columbia. (CS)

  10. NetState

    SciTech Connect

    Durgin, Nancy; Mai, Yuqing; Hutchins, James

    2005-09-01

    NetState is a distributed network monitoring system. It uses passive sensors to develop status information on a target network. Two major features provided by NetState are version and port tracking. Version tracking maintains information about software and operating systems versions. Port tracking identifies information about active TOP and UDP ports. Multiple NetState sniffers can be deployed, one at each entry point of the target network. The sniffers monitor network traffic, then send the information to the NetState server. The information is stored in centralized database which can then be accessed via standard SQL database queries or this web-based GUI, for further analysis and display.

  11. On neutrino flavor states

    NASA Astrophysics Data System (ADS)

    Ho, Chiu Man

    2012-12-01

    We review the issues associated with the construction of neutrino flavor states. We then provide a consistent proof that the flavor states are approximately well-defined only if neutrinos are ultra-relativistic or the mass differences are negligible compared to energy. However, we show that weak interactions can be consistently described by only neutrino mass eigenstates. Meanwhile, the second quantization of neutrino flavor fields generally has no physical relevance as their masses are indefinite. Therefore, the flavor states are not physical quantum states and they should simply be interpreted as definitions to denote specific linear combinations of mass eigenstates involved in weak interactions. We also briefly discuss the implication of this work for the mixing between active and heavy sterile neutrinos.

  12. Covering the State Legislature

    ERIC Educational Resources Information Center

    Hook, Stephen C.

    1975-01-01

    Describes how journalism majors at Ball State University are required to cover the annual sessions of the Indiana legislature, and discusses some of the experiences and problems that were encountered. (RB)

  13. State Health Facts

    MedlinePlus

    ... Search State Health Facts: Choose Category - or - Choose Location Demographics and the Economy Health Costs & Budgets Health ... Contact Us Employment Opportunities © 2017 Kaiser Family Foundation Privacy Policy Powered by WordPress.com VIP Follow Us ...

  14. Topological Photonic States

    NASA Astrophysics Data System (ADS)

    He, Cheng; Lin, Liang; Sun, Xiao-Chen; Liu, Xiao-Ping; Lu, Ming-Hui; Chen, Yan-Feng

    2014-01-01

    As exotic phenomena in optics, topological states in photonic crystals have drawn much attention due to their fundamental significance and great potential applications. Because of the broken time-reversal symmetry under the influence of an external magnetic field, the photonic crystals composed of magneto-optical materials will lead to the degeneracy lifting and show particular topological characters of energy bands. The upper and lower bulk bands have nonzero integer topological numbers. The gapless edge states can be realized to connect two bulk states. This topological photonic states originated from the topological property can be analogous to the integer quantum Hall effect in an electronic system. The gapless edge state only possesses a single sign of gradient in the whole Brillouin zone, and thus the group velocity is only in one direction leading to the one-way energy flow, which is robust to disorder and impurity due to the nontrivial topological nature of the corresponding electromagnetic states. Furthermore, this one-way edge state would cross the Brillouin center with nonzero group velocity, where the negative-zero-positive phase velocity can be used to realize some interesting phenomena such as tunneling and backward phase propagation. On the other hand, under the protection of time-reversal symmetry, a pair of gapless edge states can also be constructed by using magnetic-electric coupling meta-materials, exhibiting Fermion-like spin helix topological edge states, which can be regarded as an optical counterpart of topological insulator originating from the spin-orbit coupling. The aim of this article is to have a comprehensive review of recent research literatures published in this emerging field of photonic topological phenomena. Photonic topological states and their related phenomena are presented and analyzed, including the chiral edge states, polarization dependent transportation, unidirectional waveguide and nonreciprocal optical transmission, all

  15. Investigating Quantum Modulation States

    DTIC Science & Technology

    2016-03-01

    INVESTIGATING QUANTUM MODULATION STATES MARCH 2016 FINAL TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED STINFO COPY AIR...3. DATES COVERED (From - To) OCT 2012 – SEP 2015 4. TITLE AND SUBTITLE INVESTIGATING QUANTUM MODULATION STATES 5a. CONTRACT NUMBER IN-HOUSE 5b...NOTES 14. ABSTRACT This effort was primarily concerned with quantum aspects of optical communications. Two quantum communications technologies were

  16. Cluster State Quantum Computing

    DTIC Science & Technology

    2012-12-01

    implementation of quantum computation,” Fortschr. Phys. 48, 771 (2000). [Dragoman01] D. Dragoman, “Proposal for a three-qubit teleportation experiment”, Phys...CLUSTER STATE QUANTUM COMPUTING DECEMBER 2012 INTERIM TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION...From - To) NOV 2010 – OCT 2012 4. TITLE AND SUBTITLE CLUSTER STATE QUANTUM COMPUTING 5a. CONTRACT NUMBER IN-HOUSE 5b. GRANT NUMBER N/A 5c

  17. State summaries: Idaho

    USGS Publications Warehouse

    Gillerman, V.S.; Weaver, M.J.; Bennett, E.H.

    2006-01-01

    According to the United States Geological Survey (USGS), Idaho's preliminary nonfuel mineral production value jumped to $893 million in 2005. Principal minerals by value included molybdenum concentrates, phosphate rock, sand and gravel, silver and portland cement. The state ranked second in phosphate and garnet production, third in silver and pumice, fourth in molybdenum concentrate production, and 21st overall. Majority of mining increases for the year were spurred by demand for metals by China's growing economy.

  18. Solid state switch

    DOEpatents

    Merritt, Bernard T.; Dreifuerst, Gary R.

    1994-01-01

    A solid state switch, with reverse conducting thyristors, is designed to operate at 20 kV hold-off voltage, 1500 A peak, 1.0 .mu.s pulsewidth, and 4500 pps, to replace thyratrons. The solid state switch is more reliable, more economical, and more easily repaired. The switch includes a stack of circuit card assemblies, a magnetic assist and a trigger chassis. Each circuit card assembly contains a reverse conducting thyristor, a resistor capacitor network, and triggering circuitry.

  19. State of family planning.

    PubMed

    Schreiber, Courtney A; Traxler, Sarah

    2015-06-01

    Family planning and reproductive health services are uniquely impacted by policy and politics in the United States. Recent years have witnessed an unprecedented number of abortion restrictions, and research funding has decreased in related areas. Despite this, both the science and the implementation of improved family planning and abortion methods have progressed in the past decade. This article reviews the current state of family planning, as well as technologies and patient care opportunities for the future.

  20. Electronic states of WH

    NASA Astrophysics Data System (ADS)

    Ma, Zhongxin; Balasubramanian, K.

    1991-07-01

    Spectroscopic constants and potential energy curves of 15 electronic states of WH are obtained using the complete-active-space multi-configuration self-consistent field (CAS MCSCF) followed by full second-order configuration-interaction (SOCI) calculations. The spin-orbit effects are introduced using the relativistic-configuration-interaction (RCI) method. Our computations confirm the assignment of the observed emission spectrum at 6800 Å but yield different vibrational frequencies for the two observed states.

  1. State responses to biotechnology.

    PubMed

    Harris, Rebecca C

    2015-01-01

    This article reviews biotechnology legislation in the 50 states for 11 policy areas spanning 1990-2010, an era of immense growth in biotechnology, genetic knowledge, and significant policy development. Policies regarding health insurance, life insurance, long-term care insurance, DNA data bank collection, biotech research protection, biotech promotion and support, employment discrimination, genetic counselor licensing, human cloning, and genetic privacy each represent major policy responses arising from biotechnology and coinciding with key areas of state regulation (insurance, criminal justice, economic development, labor law, health and safety, privacy, and property rights). This analysis seeks to answer three questions regarding biotechnology legislation at the state level: who is acting (policy adoption), when is policy adopted (policy timing), and what is policy doing (policy content). Theoretical concerns examine state ideology (conservative or liberal), policy type (economic or moral), and the role of external events (federal law, news events, etc.) on state policy adoption. Findings suggest ideological patterns in adoption, timing, and content of biotech policy. Findings also suggest economic policies tend to be more uniform in content than moral policies, and findings also document a clear link between federal policy development, external events, and state policy response.

  2. Tripartite composite fermion states

    NASA Astrophysics Data System (ADS)

    Sreejith, G. J.; Wu, Ying-Hai; Wójs, A.; Jain, J. K.

    2013-06-01

    The Read-Rezayi wave function is one of the candidates for the fractional quantum Hall effect at filling fraction ν=2+⅗, and thereby also its hole conjugate at 2+⅖. We study a general class of tripartite composite fermion wave functions, which reduce to the Rezayi-Read ground state and quasiholes for appropriate quantum numbers, but also allow a construction of wave functions for quasiparticles and neutral excitations by analogy to the standard composite fermion theory. We present numerical evidence in finite systems that these trial wave functions capture well the low energy physics of a four-body model interaction. We also compare the tripartite composite fermion wave functions with the exact Coulomb eigenstates at 2+⅗, and find reasonably good agreement. The ground state as well as several excited states of the four-body interaction are seen to evolve adiabatically into the corresponding Coulomb states for N=15 particles. These results support the plausibility of the Read-Rezayi proposal for the 2+⅖ and 2+⅗ fractional quantum Hall effect. However, certain other proposals also remain viable, and further study of excitations and edge states will be necessary for a decisive establishment of the physical mechanism of these fractional quantum Hall states.

  3. Self-photopumped x-ray lasers from elements in the Ne-like and Ni-like ionization state

    NASA Astrophysics Data System (ADS)

    Siegrist, Michael; Staub, Felix; Jia, Fei; Feurer, Thomas; Balmer, Jürg; Nilsen, Joseph

    2017-01-01

    We report on experiments on the self-photopumped 3d 1P1→3p 1P1 and 4f 1P1→4d 1P1 laser transitions in Ne-like and Ni-like ions, respectively. Lasing on the self-photopumped laser line has been observed for the first time for a number of elements including Ne-like V, Cr, Fe, and Co as well as Ni-like Ru and Pd. We have investigated the lasing process by varying the prepulse delay, which shows a shift of the optimum main pulse to second prepulse delays towards lower values with higher atomic number Z. Time-resolved measurements showed that self-photopumped and monopole collision-pumped lasing emission occurs essentially simultaneously. Accurate wavelength measurements and calculations are shown to be in excellent agreement.

  4. State Online College Job Market: Ranking the States

    ERIC Educational Resources Information Center

    Carnevale, Anthony; Jayasundera, Tamara; Repnikov, Dmitri; Gulish, Artem

    2015-01-01

    "State Online College Job Market: Ranking the States" analyzes the online college labor market on a state-by-state basis. We examine the geographic distribution of online job ads for college graduates within industries and occupational clusters, and compare the relative strength of the online college labor market across states. We…

  5. 31 CFR 515.321 - United States; continental United States.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false United States; continental United... General Definitions § 515.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof, including the Trust Territory...

  6. 31 CFR 515.321 - United States; continental United States.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false United States; continental United... General Definitions § 515.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof, including the Trust Territory...

  7. 31 CFR 515.321 - United States; continental United States.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false United States; continental United... General Definitions § 515.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof, including the Trust Territory...

  8. 31 CFR 500.321 - United States; continental United States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States; continental United... General Definitions § 500.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof, including U.S. trust...

  9. 31 CFR 515.321 - United States; continental United States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States; continental United... General Definitions § 515.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof, including the Trust Territory...

  10. 31 CFR 515.321 - United States; continental United States.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false United States; continental United... General Definitions § 515.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof, including the Trust Territory...

  11. 31 CFR 535.321 - United States; continental United States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States; continental United... General Definitions § 535.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof including the Trust Territory...

  12. 31 CFR 535.321 - United States; continental United States.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false United States; continental United... General Definitions § 535.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof including the Trust Territory...

  13. 31 CFR 535.321 - United States; continental United States.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false United States; continental United... General Definitions § 535.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof including the Trust Territory...

  14. 31 CFR 535.321 - United States; continental United States.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false United States; continental United... General Definitions § 535.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof including the Trust Territory...

  15. 31 CFR 535.321 - United States; continental United States.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false United States; continental United... General Definitions § 535.321 United States; continental United States. The term United States means the United States and all areas under the jurisdiction or authority thereof including the Trust Territory...

  16. Intranets and Extranets at State Libraries in the United States.

    ERIC Educational Resources Information Center

    Bolt, Nancy M.

    This paper is an analysis of Intranets and Extranets at selected state libraries in the United States. The paper does not review World Wide Web sites designed for use by the general public; rather, it focuses on Web sites designed and delivered by the state library to a targeted audience, typically state government employees, state library…

  17. Stabilization of autoionizing states

    NASA Astrophysics Data System (ADS)

    Ereifej, Heider Naim

    2000-09-01

    In the first experiment, the stabilization process of doubly excited states in Barium was examined for the case when a laser field was used to induce stimulated emission of the excited core electron. Stabilization is referred to all the atoms that form a singly excited neutral state after being in a doubly excited autoionizing state. Relative to pure fluorescence, the application of a laser pulse which was long relative to the autoionization lifetime was found to increase the number of atoms that were stabilized. Shake-up spectra in which the principal quantum number of both electrons changes during the stimulated emission process was also clearly demonstrated. In the second experiment, a short laser pulse (short relative to the autoionization lifetime) was used to stimulate doubly excited Calcium atoms to form a stable configuration. Because the stimulated emission process happens on a fast time scale, more atoms were stabilized before they had a chance to autoionize. As a result, much larger enhancement factors were achieved. In the third and final experiment, a direct measurement of the oscillations between degenerate bound state configurations in a rapidly autoionizing system was clearly demonstrated. Because of the short pulse excitation, the atom was prepared in one of many accessible two-electron configurations. This state of the atom was not an energy eigenstate but a non-stationary wavepacket. The evolution of these wavepackets was monitored by changing the timing between the exciting ``pump'' laser and the stimulating ``probe'' laser.

  18. Superpowers and client states

    SciTech Connect

    Efrat, M.; Bercovitch, J.

    1987-01-01

    Throughout the world the two superpowers often conduct their global conflict by proxy, taking different sides in regional disputes. An important question of international relations is where the balance of power lies in the superpower client state relationship-how far are the interests of the superpower subordinated to those of the client state or vice versa. Taking the two case studies of the US-Israel relationship and the Soviet-Syrian relationship, this book explores the perceptions by each side of the relationship and the reality. It goes on to make general conclusions about superpower-client state relationships. Contents: Introduction; In Search of a Theoretical Framework; Client-States in Superpower Perception; Superpowers in Client States' Perception; The Case of US-Israel Relations; Israel in US Perspective; The USA in Israeli Perspective; Flows of US Civilian and Military Resources to Israel; The Case of Soviet-Syrian Relations; Syria in Soviet Perspective; The USSR in Syrian Perspective; Flows of Soviet Civilian and Military Resources to Syria; Comparative Analysis and Conclusions; Overview of the two cases studies and conclusions.

  19. Matrix product state renormalization

    NASA Astrophysics Data System (ADS)

    Bal, M.; Rams, M. M.; Zauner, V.; Haegeman, J.; Verstraete, F.

    2016-11-01

    The truncation or compression of the spectrum of Schmidt values is inherent to the matrix product state (MPS) approximation of one-dimensional quantum ground states. We provide a renormalization group picture by interpreting this compression as an application of Wilson's numerical renormalization group along the imaginary time direction appearing in the path integral representation of the state. The location of the physical index is considered as an impurity in the transfer matrix and static MPS correlation functions are reinterpreted as dynamical impurity correlations. Coarse-graining the transfer matrix is performed using a hybrid variational ansatz based on matrix product operators, combining ideas of MPS and the multiscale entanglement renormalization ansatz. Through numerical comparison with conventional MPS algorithms, we explicitly verify the impurity interpretation of MPS compression, as put forward by V. Zauner et al. [New J. Phys. 17, 053002 (2015), 10.1088/1367-2630/17/5/053002] for the transverse-field Ising model. Additionally, we motivate the conceptual usefulness of endowing MPS with an internal layered structure by studying restricted variational subspaces to describe elementary excitations on top of the ground state, which serves to elucidate a transparent renormalization group structure ingrained in MPS descriptions of ground states.

  20. Federation of State Medical Boards of the United States

    MedlinePlus

    ... Boards Representing the 70 medical boards of the United States and its territories. The Federation of State Medical ... the 70 medical and osteopathic boards of the United States and its territories. Since its founding, the FSMB ...

  1. State Trees and Arbor Days.

    ERIC Educational Resources Information Center

    Forest Service (USDA), Washington, DC.

    Provides information on state trees for each of the 50 states and the District of Columbia. Includes for each state: (1) year in which state tree was chosen; (2) common and scientific names of the tree; (3) arbor day observance; (4) address of state forester; and (5) drawings of the tree, leaf, and fruit or cone. (JN)

  2. 78 FR 4439 - United States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... Antitrust Division United States v. Oklahoma State Chiropractic Independent Physicians Association and Larry..., Stipulation, and Competitive Impact Statement have been filed with the United States District Court for the Northern District of Oklahoma in United States of America v. Oklahoma State Chiropractic...

  3. See Your State From Space!

    USGS Publications Warehouse

    ,

    2008-01-01

    Each of the 50 States in the United States is beautiful in its own way. That beauty can be seen from a unique perspective using satellite images taken from high above the Earth. These State images were created from multiple satellite images stitched together into one seamless image for each State. Names of major cities, administrative boundaries, and State flags have been added.

  4. Discorrelated quantum states

    PubMed Central

    Meyer-Scott, Evan; Tiedau, Johannes; Harder, Georg; Shalm, Lynden K.; Bartley, Tim J.

    2017-01-01

    The statistical properties of photons are fundamental to investigating quantum mechanical phenomena using light. In multiphoton, two-mode systems, correlations may exist between outcomes of measurements made on each mode which exhibit useful properties. Correlation in this sense can be thought of as increasing the probability of a particular outcome of a measurement on one subsystem given a measurement on a correlated subsystem. Here, we show a statistical property we call “discorrelation”, in which the probability of a particular outcome of one subsystem is reduced to zero, given a measurement on a discorrelated subsystem. We show how such a state can be constructed using readily available building blocks of quantum optics, namely coherent states, single photons, beam splitters and projective measurement. We present a variety of discorrelated states, show that they are entangled, and study their sensitivity to loss. PMID:28134333

  5. Topological States of Heterostructures

    NASA Astrophysics Data System (ADS)

    Usanmaz, Demet; Nath, Pinku; Plata, Jose J.; Buongiorno Nardelli, Marco; Fornari, Marco; Curtarolo, Stefano

    Topological insulators (TIs) have exotic properties, such as having insulating behavior in the bulk and metallic states at the surface [1]. Observations of metallic states rely on the spin-orbit induced band inversion in bulk materials and are protected by time-reversal symmetry or crystal symmetry [ 2 ]. These remarkable characteristics of TIs give rise to various applications from spintronics to quantum computers. In order to broaden the range of applications of TIs and make it more effective, an exploration of high quality heterostructures are required. Creating heterostructures of TIs has recently demonstrated to be advantageous for controlling electronic properties [3]. Inspired by these interesting properties, we have investigated the topological interface states of heterostructures.

  6. Parametric State Space Structuring

    NASA Technical Reports Server (NTRS)

    Ciardo, Gianfranco; Tilgner, Marco

    1997-01-01

    Structured approaches based on Kronecker operators for the description and solution of the infinitesimal generator of a continuous-time Markov chains are receiving increasing interest. However, their main advantage, a substantial reduction in the memory requirements during the numerical solution, comes at a price. Methods based on the "potential state space" allocate a probability vector that might be much larger than actually needed. Methods based on the "actual state space", instead, have an additional logarithmic overhead. We present an approach that realizes the advantages of both methods with none of their disadvantages, by partitioning the local state spaces of each submodel. We apply our results to a model of software rendezvous, and show how they reduce memory requirements while, at the same time, improving the efficiency of the computation.

  7. State summaries: Colorado

    USGS Publications Warehouse

    Keller, J.; Carroll, C.; Widmann, B.

    2006-01-01

    According to the Colorado Geological Survey (CGS), Colorado's mining industry enjoyed a record-breaking year in 2005. For the whole year, the total value of nonfuel minerals, coal and uranium produced in the state in 2005 amounted to $2.4 billion. The production value of $1.52 billion in the nonfuel sector broke the previous record of $1.3 billion set in 1980, and is 60% higher than the revised 2004 CGS estimate of $950.5 million. The United States Geological Survey (USGS) ranked Colorado ninth among the states in nonfuel mineral value, up from 17th in 2004. About $1 billion of the nonfuel total is from metal mining. New record-high productions were achieved not only for molybdenum but also for coal and goal.

  8. Discorrelated quantum states.

    PubMed

    Meyer-Scott, Evan; Tiedau, Johannes; Harder, Georg; Shalm, Lynden K; Bartley, Tim J

    2017-01-30

    The statistical properties of photons are fundamental to investigating quantum mechanical phenomena using light. In multiphoton, two-mode systems, correlations may exist between outcomes of measurements made on each mode which exhibit useful properties. Correlation in this sense can be thought of as increasing the probability of a particular outcome of a measurement on one subsystem given a measurement on a correlated subsystem. Here, we show a statistical property we call "discorrelation", in which the probability of a particular outcome of one subsystem is reduced to zero, given a measurement on a discorrelated subsystem. We show how such a state can be constructed using readily available building blocks of quantum optics, namely coherent states, single photons, beam splitters and projective measurement. We present a variety of discorrelated states, show that they are entangled, and study their sensitivity to loss.

  9. Smallest chimera states

    NASA Astrophysics Data System (ADS)

    Maistrenko, Yuri; Brezetsky, Serhiy; Jaros, Patrycja; Levchenko, Roman; Kapitaniak, Tomasz

    2017-01-01

    We demonstrate that chimera behavior can be observed in small networks consisting of three identical oscillators, with mutual all-to-all coupling. Three different types of chimeras, characterized by the coexistence of two coherent oscillators and one incoherent oscillator (i.e., rotating with another frequency) have been identified, where the oscillators show periodic (two types) and chaotic (one type) behaviors. Typical bifurcations at the transitions from full synchronization to chimera states and between different types of chimeras have been described. Parameter regions for the chimera states are obtained in the form of Arnold tongues, issued from a singular parameter point. Our analysis suggests that chimera states can be observed in small networks relevant to various real-world systems.

  10. Discrete density of states

    NASA Astrophysics Data System (ADS)

    Aydin, Alhun; Sisman, Altug

    2016-03-01

    By considering the quantum-mechanically minimum allowable energy interval, we exactly count number of states (NOS) and introduce discrete density of states (DOS) concept for a particle in a box for various dimensions. Expressions for bounded and unbounded continua are analytically recovered from discrete ones. Even though substantial fluctuations prevail in discrete DOS, they're almost completely flattened out after summation or integration operation. It's seen that relative errors of analytical expressions of bounded/unbounded continua rapidly decrease for high NOS values (weak confinement or high energy conditions), while the proposed analytical expressions based on Weyl's conjecture always preserve their lower error characteristic.

  11. State summaries: Illinois

    USGS Publications Warehouse

    Lasemi, Z.; Mikulic, Donald G.

    2006-01-01

    According to the United States Geological Survey (USGS), Illinois ranked third in the amount of crushed stone produced from underground mining operations. In 2004, Illinois produced more than 76.5 Mt of crushed stone and 38.7 Mt of sand-and-gravel. Preliminary data for 2005 showed an increase in the production of crushed stone and a slight decrease in the production of sand-and-gravel. The state remained 16th in total value of nonfuel mineral production. In decreasing order of value, the minerals produced included crushed stone, cement, construction sand and gravel, lime, clay, peat, tripoli, industrial sand, crushed sandstone and gemstone.

  12. State summaries: Oklahoma

    USGS Publications Warehouse

    Krukowski, S.T.

    2006-01-01

    In 2005, Oklahoma mines produced both industrial minerals and coal. No metals were mined in the state. Based on value, leading industrial minerals include crushed stone followed by cement, construction sand and gravel, industrial sand and gravel, iodine and gypsum. The Oklahoma Department of Mines (ODOM) reported that more than 343 mine operators produced nonfuel minerals from 405 mines in the state. However, 530 mining permitted sites were on file. The Oklahoma Miner Training Institute (OMTI) held 239 classes for 33,768 classroom hours of instruction, in which 84 coal miners and 4,587 metal/nonmetal miners were trained.

  13. Parameter estimating state reconstruction

    NASA Technical Reports Server (NTRS)

    George, E. B.

    1976-01-01

    Parameter estimation is considered for systems whose entire state cannot be measured. Linear observers are designed to recover the unmeasured states to a sufficient accuracy to permit the estimation process. There are three distinct dynamics that must be accommodated in the system design: the dynamics of the plant, the dynamics of the observer, and the system updating of the parameter estimation. The latter two are designed to minimize interaction of the involved systems. These techniques are extended to weakly nonlinear systems. The application to a simulation of a space shuttle POGO system test is of particular interest. A nonlinear simulation of the system is developed, observers designed, and the parameters estimated.

  14. Hypercoagulable states and strokes.

    PubMed

    Matijevic, Nena; Wu, Kenneth K

    2006-07-01

    Several hematologic disorders and hemostatic defects increase risk of ischemic stroke. A common feature of these disorders is the creation of a prothrombotic state, now commonly referred to as "hypercoagulable state." Hematologic diseases such as essential thrombocythemia, polycythemia vera, and thrombotic thrombocytopenic purpura clearly cause stroke. Effective treatment is now available for these disorders. Association of hemostatic defects with stroke risk is still at the investigational stage. Although a number of factors such as soluble thrombomodulin, fibrinogen, factor VIII, von Willebrand factor, and plasminogen activator inhibitor-1 are associated with stroke risk, their predictive values remain unknown. Furthermore, causal relationship has not been established.

  15. Solid state switch

    DOEpatents

    Merritt, B.T.; Dreifuerst, G.R.

    1994-07-19

    A solid state switch, with reverse conducting thyristors, is designed to operate at 20 kV hold-off voltage, 1,500 A peak, 1.0 [mu]s pulsewidth, and 4,500 pps, to replace thyratrons. The solid state switch is more reliable, more economical, and more easily repaired. The switch includes a stack of circuit card assemblies, a magnetic assist and a trigger chassis. Each circuit card assembly contains a reverse conducting thyristor, a resistor capacitor network, and triggering circuitry. 6 figs.

  16. The solid state

    SciTech Connect

    Guinier, A.; Remi, J.

    1989-01-01

    This book is an introduction to the solid state for students and non-specialists. Authors aim to relate the macroscopic properties of solids (usually crystalline) to models of their atomic structure. Thermal expansion, the electronic conductivity of metals, ferromagnetism, plastic deformation and diffusion in real systems are among specific topics addressed. Advanced mathematical explanations are set off from the rest of the text in boxed sections for readers wishing a more indepth treatment of topics. Abbreviated bibliography included. For academic collections in solid state physics.

  17. Administering Our State Library Agencies

    ERIC Educational Resources Information Center

    DuFrane, Gerard

    1970-01-01

    A satire on the application of scientific management principles to a state library agency. Covers relationships of the state librarian to staff, the profession, and state and federal governments. (Author/JS)

  18. Quantum state targeting

    SciTech Connect

    Rudolph, Terry; Spekkens, Robert W.

    2004-11-01

    We introduce a primitive for quantum cryptography that we term 'state targeting'. We show that increasing one's probability of success in this task above a minimum amount implies an unavoidable increase in the probability of a particular kind of failure. This is analogous to the unavoidable disturbance to a quantum state that results from gaining information about its identity, and can be shown to be a purely quantum effect. We solve various optimization problems for state targeting that are useful for the security analysis of two-party cryptographic tasks implemented between remote antagonistic parties. Although we focus on weak coin flipping, the results are significant for other two-party protocols, such as strong coin flipping, partially binding and concealing bit commitment, and bit escrow. Furthermore, the results have significance not only for the traditional notion of security in cryptography, that of restricting a cheater's ability to bias the outcome of the protocol, but also for a different notion of security that arises only in the quantum context, that of cheat sensitivity. Finally, our analysis leads to some interesting secondary results, namely, a generalization of Uhlmann's theorem and an operational interpretation of the fidelity between two mixed states.

  19. States Address Academic Concerns

    ERIC Educational Resources Information Center

    Hoff, David J.

    2005-01-01

    State and local officials are slowly untangling complicated webs of accountability, testing, and graduation policies, hoping to give thousands of students displaced by Hurricane Katrina a better handle on their academic standing. While officials in Texas, Tennessee, and Alabama offered some guidance to such students, school leaders in…

  20. State Virtual Libraries

    ERIC Educational Resources Information Center

    Pappas, Marjorie L.

    2003-01-01

    Virtual library? Electronic library? Digital library? Online information network? These all apply to the growing number of Web-based resource collections managed by consortiums of state library entities. Some, like "INFOhio" and "KYVL" ("Kentucky Virtual Library"), have been available for a few years, but others are just starting. Searching for…

  1. Protein states and proteinquakes.

    PubMed Central

    Ansari, A; Berendzen, J; Bowne, S F; Frauenfelder, H; Iben, I E; Sauke, T B; Shyamsunder, E; Young, R D

    1985-01-01

    After photodissociation of carbon monoxide bound to myoglobin, the protein relaxes to the deoxy equilibrium structure in a quake-like motion. Investigation of the proteinquake and of related intramolecular equilibrium motions shows that states and motions have a hierarchical glass-like structure. PMID:3860839

  2. Variational transition state theory

    SciTech Connect

    Truhlar, D.G.

    1993-12-01

    This research program involves the development of variational transition state theory (VTST) and semiclassical tunneling methods for the calculation of gas-phase reaction rates and selected applications. The applications are selected for their fundamental interest and/or their relevance to combustion.

  3. States of Emergency

    ERIC Educational Resources Information Center

    Mayer, Caroline E.

    2012-01-01

    Given the stakes and the current economic climate, U.S. higher education officials across the country are stepping up their advocacy efforts, making their voices louder and more persistent than ever. They are vying for the attention of states struggling with increased demands for limited revenues, most choosing to divert dollars from higher…

  4. Solid-State Devices.

    ERIC Educational Resources Information Center

    Sutliff, Ronald D.; And Others

    This self-study course is designed to familiarize Marine Corps enlisted personnel with the principles of solid-state devices and their functions. The course contains four study units. Each study unit begins with a general objective, which is a statement of what the student should learn from the unit. The study units are divided into numbered work…

  5. Indians of Washington State.

    ERIC Educational Resources Information Center

    Washington Office of the State Superintendent of Public Instruction, Olympia.

    Maps, photographs, and illustrations are included in this introductory history of Indians in Washington state. The tribal groups of the area are classified by geographic and cultural region as Coastal, Puget Sound, and Plateau tribes, and the majority of the resource booklet provides information about the history and culture of each group.…

  6. State Skill Standards: Photography

    ERIC Educational Resources Information Center

    Howell, Frederick; Reed, Loretta; Jensen, Capra; Robison, Gary; Taylor, Susan; Pavesich, Christine

    2007-01-01

    The Department of Education has undertaken an ambitious effort to develop statewide skill standards for all content areas in career and technical education. The standards in this document are for photography programs and are designed to clearly state what the student should know and be able to do upon completion of an advanced high-school program.…

  7. Energy States of Molecules

    ERIC Educational Resources Information Center

    Hollenberg, J. Leland

    1970-01-01

    Discusses molecular spectroscopy arising from transitions within rotational, vibrational, and electronic energy states. Using quantum mechanical formuli, the author describes how these spectroscopic methods can be used to determine internuclear distances, bond energies, bond angles, dipole moments, and other details. Concludes with a selected…

  8. Church and State.

    ERIC Educational Resources Information Center

    National Forum: Phi Kappa Phi Journal, 1988

    1988-01-01

    Church and state is discussed in four articles: "Religiously Inspired Censorship in Public Schools" (John H. Buchanan, 34-35); "Public Funding of Education in Religious Schools" (Eugene W. Hickok, Jr., 36-38); "Neutrality in Teaching Moral Principles in Public Schools: (Francis William O'Brien, 39-40); and "The Most…

  9. States' Average College Tuition.

    ERIC Educational Resources Information Center

    Eglin, Joseph J., Jr.; And Others

    This report presents statistical data on trends in tuition costs from 1980-81 through 1995-96. The average tuition for in-state undergraduate students of 4-year public colleges and universities for academic year 1995-96 was approximately 8.9 percent of median household income. This figure was obtained by dividing the students' average annual…

  10. State Archaeological Education Programs.

    ERIC Educational Resources Information Center

    Butler, William B., Ed.

    The focus of this conference was on programs and experiences in public archaeological education in the Plains states and immediate neighbors. The contents lists the following papers: (1) "Introduction to the Symposium" (William B. Butler); (2) "Archaeological Educational Programs in Colorado" (Kevin D. Black); (3) "Statewide Archaeological…

  11. Keystone State of Confusion

    ERIC Educational Resources Information Center

    Stuart, Reginald

    2009-01-01

    When high school seniors begin searching for the best school to fit their higher education goals, they may need a road map, tour guide and interpreter to help them sort through Pennsylvania's higher education universe. For sure there are seemingly endless choices--public, private, large, small, urban and rural. The Keystone State boasts nearly 200…

  12. United States Attorney Prosecutions

    DTIC Science & Technology

    1993-10-01

    property of CocaCola Bottling Company, Fayetteville, North Carolina, of a value in excess of $100.00, in violation of Title 18 United States Code, Section...another, to-wit: a Cocacola soft drink machine, the amount of damage to said personal property being more than $200.00, in violation of North Carolina

  13. Solid State Lighting

    SciTech Connect

    Hastbacka, Mildred; Dieckmann, John; Bouza, Antonio

    2013-03-30

    The article discusses solid state lighting technologies. This topic was covered in two previous ASHRAE Journal columns (2010). This article covers advancements in technologies and the associated efficacies. The life-cycle, energy savings and market potential of these technologies are addressed as well.

  14. Florida: State Policy Brief

    ERIC Educational Resources Information Center

    Corbett, Julie

    2015-01-01

    This brief is one in a series highlighting state policies, regulations, practices, laws, or other tools intended to create the necessary conditions for school and/or district turnaround. Each brief includes an overview of the relevant turnaround tool, its development process, its impact, and lessons learned that could assist other education…

  15. Engaging Future Failing States

    DTIC Science & Technology

    2011-03-23

    disparity, overpopulation , food security, health services availability, migration pressures, environmental degradation, personal and 22 community...demographic pressures; refugees and displaced persons movement; group grievances; chronic human flight; and uneven development. The economic indicators...include: economic output; and legitimacy of the state. The political indicators include: public services; human rights; security; factionilization

  16. Colorado State University

    ERIC Educational Resources Information Center

    McKelfresh, David A.; Bender, Kim K.

    2009-01-01

    Colorado State University (CSU) is located in Fort Collins, which is a midsize city of 134,000 situated in Northern Colorado at the western edge of the Great Plains and at the base of the Rocky Mountains. CSU's total enrollment is approximately 25,000 students. The Division of Student Affairs comprises 30 departments organized into programmatic…

  17. GENIE final state interactions

    SciTech Connect

    Dytman, Steven

    2015-10-15

    Final state interactions are an important component of any neutrino-nucleus Monte Carlo program. GENIE has 2 FSI programs which serve different purposes. Each has fair-good agreement with a wide range of hadron-nucleus data. Recent improvements and planned advancements are described.

  18. Adams v. State.

    PubMed

    1998-01-01

    The Supreme Court of Georgia, on 4 May 1998, held that a state statute permitting a crime victim who is significantly exposed to HIV request an HIV blood test on the person charged with the crime and arrested does not violate the Fourth Amendment right against unreasonable searches, nor does it violate privacy or equal protection rights. Malik Adams attacked and struggled with police officers during arrest. In the struggle, Adams's and an officer's hands, on which there were bleeding wounds, came in contact. Even though Adams did not have any outward AIDS symptoms, the State filed a motion to compel HIV testing. The Supreme Court of Georgia held that, because the statute compelling HIV testing serves the compelling state interest of preventing the public's exposure to HIV, the search, in this case the taking and sampling of blood, was reasonable. The statute also did not violate Adams's right to privacy or state or federal equal protection clauses. The judgment of the Superior court was affirmed.

  19. Adams v. State.

    PubMed

    1998-01-01

    Court Decision: 498 South Eastern Reporter, 2d Series 268; 1998 May 4 (date of decision). The Supreme Court of Georgia held that a state statute permitting a crime victim who is significantly exposed to HIV request an HIV blood test on the person charged with the crime and arrested does not violate the Fourth Amendment right against unreasonable searches, nor does it violate privacy or equal protection rights. Malik Adams attacked and struggled with police officers during arrest. In the struggle, Adams's and an officer's hands, on which there were bleeding wounds, came in contact. Even though Adams did not have any outward AIDS symptoms, the State filed a motion to compel HIV testing. The Supreme Court of Georgia held that, because the statute compelling HIV testing serves the compelling state interest of preventing the public's exposure to HIV, the search, in this case the taking and sampling of blood, was reasonable. The statute also did not violate Adams's right to privacy or state or federal equal protection clauses.

  20. State Skill Standards: Welding

    ERIC Educational Resources Information Center

    Pointer, Mike; Naylor, Randy; Warden, John; Senek, Gene; Shirley, Charles; Lefcourt, Lew; Munson, Justin; Johnson, Art

    2005-01-01

    The Department of Education has undertaken an ambitious effort to develop statewide occupational skill standards. The standards in this document are for welding programs and are designed to clearly state what the student should know and be able to do upon completion of an advanced high-school program. The writing team determined that any statewide…

  1. State Skill Standards: Metalworking

    ERIC Educational Resources Information Center

    Pointer, Mike; Naylor, Randy; Warden, John; Senek, Gene; Shirley, Charles; Lefcourt, Lew; Munson, Justin; Johnson, Art

    2005-01-01

    The Department of Education has undertaken an ambitious effort to develop statewide occupational skill standards. The standards in this document are for metalworking programs and are designed to clearly state what the student should know and be able to do upon completion of an advanced high-school program. The writing team determined that any…

  2. Emotional state and efficiency

    NASA Technical Reports Server (NTRS)

    Ovchinnikova, O. V.

    1973-01-01

    An investigation was made of the effect of emotional states-negative and positive- on work performance. Data cover intensity of emotional arousal, personality characteristics of person involved, typological features of person's nervous system, emotional stability of person, and past experience of person. Particular attention was given to emotional stress effects on efficiency, given modern working conditions.

  3. Mississippi: State Policy Brief

    ERIC Educational Resources Information Center

    Corbett, Julie

    2014-01-01

    This brief is one in a series highlighting state policies, regulations, practices, laws, or other tools intended to create the necessary conditions for school and/or district turnaround. Each brief includes an overview of the relevant turnaround tool, its development process, its impact, and lessons learned that could assist other education…

  4. Designing State Aid Formulas

    ERIC Educational Resources Information Center

    Zhao, Bo; Bradbury, Katharine

    2009-01-01

    This paper designs a new equalization-aid formula based on fiscal gaps of local communities. When states are in transition to a new local aid formula, the issue of whether and how to hold existing aid harmless poses a challenge. The authors show that some previous studies and the formulas derived from them give differential weights to existing and…

  5. State Energy Resilience Framework

    SciTech Connect

    Phillips, J.; Finster, M.; Pillon, J.; Petit, F.; Trail, J.

    2016-12-01

    The energy sector infrastructure’s high degree of interconnectedness with other critical infrastructure systems can lead to cascading and escalating failures that can strongly affect both economic and social activities.The operational goal is to maintain energy availability for customers and consumers. For this body of work, a State Energy Resilience Framework in five steps is proposed.

  6. Quantum Transition State Theory

    NASA Astrophysics Data System (ADS)

    Waalkens, Holger

    2009-03-01

    The main idea of Wigner's transition state theory (TST) is to compute reaction rates from the flux through a dividing surface placed between reactants and products. In order not to overestimate the rate the dividing surface needs to have the no- recrossing property, i.e. reactive trajectories cross the dividing surface exactly once, and nonreactive trajectories do not cross it at all. The long standing problem of how to construct such a diving surface for multi-degree-of-freedom systems was solved only recently using ideas from dynamical systems theory. Here a normal form allows for a local decoupling of the classical dynamics which leads to the explicit construction of the phase space structures that govern the reaction dynamics through transition states. The dividing surface is spanned by a normally hyperbolic manifold which is the mathematical manifestation of the transition state as an unstable invariant subsystem of one degree of freedom less than the full system. The mere existence of a quantum version of TST is discussed controversially in the literature. The key isssue is the presence of quantum mechanical tunneling which prohibits the existence of a local theory analogous to the classical case. Various approaches have been devloped to overcome this problem by propagating quantum wavefunctions through the transition state region. These approaches have in common that they are computationally very expensive which seriously limits their applicability. In contrast the approach by Roman Schubert, Stephen Wiggins and myself is local in nature. A quantum normal form allows us to locally decouple the quantum dynamics to any desired order in Planck's constant. This yields not only the location of the scattering and resonance wavefunctions relative to the classical phase space structures, but also leads to very efficient algorithms to compute cumulative reaction probabilities and Gamov-Siegert resonances which are the quantum imprints of the transition state.

  7. Quantumness of spin-1 states

    NASA Astrophysics Data System (ADS)

    Bohnet-Waldraff, Fabian; Braun, D.; Giraud, O.

    2016-01-01

    We investigate quantumness of spin-1 states, defined as the Hilbert-Schmidt distance to the convex hull of spin coherent states. We derive its analytic expression in the case of pure states as a function of the smallest eigenvalue of the Bloch matrix and give explicitly the closest classical state for an arbitrary pure state. Numerical evidence is given that the exact formula for pure states provides an upper bound on the quantumness of mixed states. Due to the connection between quantumness and entanglement we obtain new insights into the geometry of symmetric entangled states.

  8. Implementing the Common Core State Standards: State Spotlights

    ERIC Educational Resources Information Center

    Council of Chief State School Officers, 2013

    2013-01-01

    As of the 2012-2013 school year, over 20 states have formally moved to the Common Core State Standards being used as the learning expectations for all students across the state, and the remainder will be doing so in the 2014-2015 school year. This document highlights state initiatives that are supporting Common Core implementation in the following…

  9. State Budgetary Assumptions. State Fiscal Brief No. 36.

    ERIC Educational Resources Information Center

    Boyd, Donald J.; Davis, Elizabeth I.

    When states prepare their budgets, they usually base revenue and expenditure projections upon forecasts of national and state economic and demographic trends. This brief presents findings of a Center for the Study of the States survey that asked state budget offices what they were assuming for many key variables. The survey obtained 41 state…

  10. The State "of" State U.S. History Standards 2011

    ERIC Educational Resources Information Center

    Stern, Sheldon M.; Stern, Jeremy A.

    2011-01-01

    This study is the Thomas B. Fordham Institute's first review of the quality of state U.S. history standards since 2003. Key findings include: (1) A majority of states' standards are mediocre-to-awful. The average grade across "all" states is barely a D. In twenty-eight jurisdictions--a majority of states--the history standards earn Ds or…

  11. Study of di-pion Bottomonium Transitions and Search for the h_b(1P) State

    SciTech Connect

    Lees, J.P.; Poireau, V.; Tisserand, V.; Garra Tico, J.; Grauges, E.; Martinelli, M.; Milanes, D.A.; Palano, A.; Pappagallo, M.; Eigen, G.; Stugu, B.; Sun, L.; Brown, D.N.; Kerth, L.T.; Kolomensky, Yu.G.; Lynch, G.; Koch, H.; Schroeder, T.; Asgeirsson, D.J.; Hearty, C.; Mattison, T.S.; /British Columbia U. /Brunel U. /Novosibirsk, IYF /UC, Irvine /UC, Riverside /UC, Santa Barbara /UC, Santa Cruz /Caltech /Cincinnati U. /Colorado U. /Colorado State U. /Dortmund U. /Dresden, Tech. U. /Ecole Polytechnique /Edinburgh U. /INFN, Ferrara /INFN, Ferrara /Ferrara U. /INFN, Ferrara /Frascati /INFN, Genoa /Genoa U. /INFN, Genoa /INFN, Genoa /Genoa U. /INFN, Genoa /Indian Inst. Tech., Guwahati /Harvard U. /Harvey Mudd Coll. /Heidelberg U. /Humboldt U., Berlin /Imperial Coll., London /Iowa State U. /Iowa State U. /Johns Hopkins U. /Paris U., VI-VII /LLNL, Livermore /Liverpool U. /Queen Mary, U. of London /Royal Holloway, U. of London /Royal Holloway, U. of London /Louisville U. /Mainz U., Inst. Kernphys. /Manchester U. /Maryland U. /Massachusetts U., Amherst /MIT /McGill U. /INFN, Milan /Milan U. /INFN, Milan /INFN, Milan /Milan U. /Mississippi U. /Montreal U. /INFN, Naples /Naples U. /NIKHEF, Amsterdam /NIKHEF, Amsterdam /Notre Dame U. /Ohio State U. /Oregon U. /INFN, Padua /Padua U. /INFN, Padua /INFN, Padua /Padua U. /Paris U., VI-VII /INFN, Perugia /Perugia U. /INFN, Pisa /Pisa U. /INFN, Pisa /Pisa, Scuola Normale Superiore /INFN, Pisa /Pisa U. /INFN, Pisa /INFN, Pisa /Pisa U. /INFN, Pisa /Princeton U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /INFN, Rome /Rome U. /INFN, Rome /Rostock U. /Rutherford /DAPNIA, Saclay /SLAC /South Carolina U. /Southern Methodist U. /Stanford U., Phys. Dept. /SUNY, Albany /Tel Aviv U. /Tennessee U. /Texas Nuclear Corp., Austin /Texas U., Dallas /INFN, Turin /Turin U. /INFN, Trieste /Trieste U. /Valencia U. /Victoria U. /Warwick U. /Wisconsin U., Madison

    2011-12-09

    We study inclusive di-pion decays using a sample of 108 x 10{sup 6} {Upsilon}(3S) events recorded with the BABAR detector. We search for the decay mode {Upsilon}(3S) {yields} {pi}{sup +}{pi}{sup -}h{sub b} (1P) and find no evidence for the bottomonium spin-singlet state h{sub b}(1P) in the invariant mass distribution recoiling against the {pi}{sup +}{pi}{sup -} system. Assuming the h{sub b}(1P) mass to be 9.900 GeV/c{sup 2}, we measure the upper limit on the branching fraction {Beta}[{Upsilon}(3S) {yields} {pi}{sup +}{pi}{sup -}h{sub b}(1P)] < 1.2 x 10{sup -4}, at 90% confidence level. We also investigate the {chi}{sub bJ}(2P) {yields} {pi}{sup +}{pi}{sup -} {chi}{sub bJ}(1P), {Upsilon}(3S) {yields} {pi}{sup +}{pi}{sup -}{Upsilon}(2S), and {Upsilon}(2S) {yields} {pi}{sup +}{pi}{sup -}{Upsilon}(1S) di-pion transitions and present an improved measurement of the branching fraction of the {Upsilon}(3S) {yields} {pi}{sup +}{pi}{sup -}{Upsilon}(2S) decay and of the {Upsilon}(3S) - {Upsilon}(2S) mass difference.

  12. Theoretical energies for the n = 1 and 2 states of the helium isoelectronic sequence up to Z = 100

    NASA Technical Reports Server (NTRS)

    Drake, G. W.

    1988-01-01

    The unified method described previously for combining high-precision nonrelativistic variational calculations with relativistic and quantum electrodynamic corrections is applied to the 1s2 1S0, 1s2s 1S0, 1s2s 1S0, 1s2s 3S1, 1s2p 1P1, and 1s2p 3P(0.1,2) states of helium-like ions. Detailed tabulations are presented for all ions in the range Z = 2-100 and are compared with a wide range of experimental data up to (Kr-34)+. The results for (U-90)+ significantly alter the recent Lamb shift measurement of Munger and Gould (1986) from 70.4 + or - 8.3 to 71.0 + or - 8.3 eV, in comparison with a revised theoretical value of 74.3 + or - 0.4 eV. The improved agreement is due to the inclusion of higher order two-electron corrections in the present work.

  13. Analysis of state Superfund programs: 50 state study. 1998 update

    SciTech Connect

    1998-12-31

    States have remediated over 40,000 contaminated sites not on the federal Superfund list. ELI`s latest analysis of state Superfund programs examines the cleanup programs of all 50 states, Puerto Rico, and the District of Columbia. The study provides the most current data on state statutes, program organization, staffing, funding, expenditures, cleanup standards, and cleanup activities, voluntary cleanup programs and brownfields programs. State and federal policymakers and attorneys working on non-NPL sites should find this study useful.

  14. Solid State Laser

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The Titan-CW Ti:sapphire (titanium-doped sapphire) tunable laser is an innovation in solid-state laser technology jointly developed by the Research and Solid State Laser Divisions of Schwartz Electro-optics, Inc. (SEO). SEO is producing the laser for the commercial market, an outgrowth of a program sponsored by Langley Research Center to develop Ti:sapphire technology for space use. SEO's Titan-CW series of Ti:sapphire tunable lasers have applicability in analytical equipment designed for qualitative analysis of carbohydrates and proteins, structural analysis of water, starch/sugar analyses, and measurements of salt in meat. Further applications are expected in semiconductor manufacture, in medicine for diagnosis and therapy, and in biochemistry.

  15. Neurobiology of Aversive States

    PubMed Central

    Umberg, Erin N.; Pothos, Emmanuel N.

    2011-01-01

    Hoebel and colleagues are often known as students of reward and how it is coded in the CNS. This article, however, attempts to focus on the significant advances by Hoebel and others in dissecting out behavioral components of distinct aversive states and in understanding the neurobiology of aversion and the link between aversive states and addictive behaviors. Reward and aversion are not necessarily dichotomous and may reflect an affective continuum contingent upon environmental conditions. Descriptive and mechanistic studies pioneered by Bart Hoebel have demonstrated that the shift in the reward-aversion spectrum may be, in part, a result of changes in central dopamine/ACh ratio, particularly in the NAc. The path to aversion appears to include a specific neurochemical signature: reduced dopamine activity and increased ACh activity in “reward centers” of the brain. Opioid receptors may have a neuromodulatory role on both of these neurotransmitters. PMID:21549137

  16. Parallel Polarization State Generation

    NASA Astrophysics Data System (ADS)

    She, Alan; Capasso, Federico

    2016-05-01

    The control of polarization, an essential property of light, is of wide scientific and technological interest. The general problem of generating arbitrary time-varying states of polarization (SOP) has always been mathematically formulated by a series of linear transformations, i.e. a product of matrices, imposing a serial architecture. Here we show a parallel architecture described by a sum of matrices. The theory is experimentally demonstrated by modulating spatially-separated polarization components of a laser using a digital micromirror device that are subsequently beam combined. This method greatly expands the parameter space for engineering devices that control polarization. Consequently, performance characteristics, such as speed, stability, and spectral range, are entirely dictated by the technologies of optical intensity modulation, including absorption, reflection, emission, and scattering. This opens up important prospects for polarization state generation (PSG) with unique performance characteristics with applications in spectroscopic ellipsometry, spectropolarimetry, communications, imaging, and security.

  17. Cutting state identification

    SciTech Connect

    Berger, B.S.; Minis, I.; Rokni, M.

    1997-12-31

    Cutting states associated with the orthogonal cutting of stiff cylinders are identified through an analysis of the singular values of a Toeplitz matrix of third order cumulants of acceleration measurements. The ratio of the two pairs of largest singular values is shown to differentiate between light cutting, medium cutting, pre-chatter and chatter states. Sequences of cutting experiments were performed in which either depth of cut or turning frequency was varied. Two sequences of experiments with variable turning frequency and five with variable depth of cut, 42 cutting experiments in all, provided a database for the calculation of third order cumulants. Ratios of singular values of cumulant matrices find application in the analysis of control of orthogonal cutting.

  18. Parallel Polarization State Generation

    PubMed Central

    She, Alan; Capasso, Federico

    2016-01-01

    The control of polarization, an essential property of light, is of wide scientific and technological interest. The general problem of generating arbitrary time-varying states of polarization (SOP) has always been mathematically formulated by a series of linear transformations, i.e. a product of matrices, imposing a serial architecture. Here we show a parallel architecture described by a sum of matrices. The theory is experimentally demonstrated by modulating spatially-separated polarization components of a laser using a digital micromirror device that are subsequently beam combined. This method greatly expands the parameter space for engineering devices that control polarization. Consequently, performance characteristics, such as speed, stability, and spectral range, are entirely dictated by the technologies of optical intensity modulation, including absorption, reflection, emission, and scattering. This opens up important prospects for polarization state generation (PSG) with unique performance characteristics with applications in spectroscopic ellipsometry, spectropolarimetry, communications, imaging, and security. PMID:27184813

  19. Valence and L-shell photoionization of Cl-like argon using R-matrix techniques

    NASA Astrophysics Data System (ADS)

    Tyndall, N. B.; Ramsbottom, C. A.; Ballance, C. P.; Hibbert, A.

    2016-02-01

    Photoionization cross-sections are obtained using the relativistic Dirac Atomic R-matrix Codes (DARC) for all valence and L-shell energy ranges between 27 and 270 eV. A total of 557 levels arising from the dominant configurations 3s23p4, 3s3p5, 3p6, 3s23p3[3d, 4s, 4p], 3p53d, 3s23p23d2, 3s3p43d, 3s3p33d2 and 2s22p53s23p5 have been included in the target wavefunction representation of the Ar III ion, including up to 4p in the orbital basis. We also performed a smaller Breit-Pauli (BP) calculation containing the lowest 124 levels. Direct comparisons are made with previous theoretical and experimental work for both valence shell and L-shell photoionization. Excellent agreement was found for transitions involving the 2Po initial state to all allowed final states for both calculations across a range of photon energies. A number of resonant states have been identified to help analyse and explain the nature of the spectra at photon energies between 250 and 270 eV.

  20. Solid State Research

    NASA Technical Reports Server (NTRS)

    Shaver, David C.

    1995-01-01

    This report covers in detail the research work of the Solid State Division at Lincoln Laboratory for the period 1 May-31 July 1995. The topics covered are: Electrooptical Devices, Quantum Electronics, Materials Research, Submicrometer Technology, High Speed Electronics, Microelectronics, and analog device technology. Funding is provided primarily by the Air Force, with additional Support provided by the Army, ARPA, Navy, BMDO, NASA and NIST.

  1. Solid State Research

    NASA Technical Reports Server (NTRS)

    Shaver, David C.

    1996-01-01

    This report covers in detail the research work of the Solid State Division at Lincoln Laboratory for the period 1 May - 31 July 1996. The topics covered are Electrooptical Devices, Quantum Electronics, Materials Research, Submicrometer Technology, High Speed Electronics, Microelectronics, and Analog Device Technology. Funding is provided primarily by the Air Force, with additional Support provided by the Army, DARPA, Navy, BMDO, NASA, and NIST.

  2. United States earthquakes, 1984

    SciTech Connect

    Stover, C.W.

    1988-01-01

    The report contains information for eartthquakes in the 50 states and Puerto Rico and the area near their shorelines. The data consist of earthquake locations (date, time, geographic coordinates, depth, and magnitudes), intensities, macroseismic information, and isoseismal and seismicity maps. Also, included are sections detailing the activity of seismic networks operated by universities and other government agencies and a list of results form strong-motion seismograph records.

  3. Solid State Research

    DTIC Science & Technology

    2010-08-26

    underneath to a high-resistivity buffer. This new method can be used to integrate quantum devices with a transistor, and maintains a highly planar surface...IEEE Electron Device Lett. 18,489(1997) Tunability of Microstrip Ferrite Resonator in the Partially Magnetized State G. F. Dionne D. E. Oates IEEE...University Park, Pennsylvania, 1 December 1997 Internal Cylindrical Magnetron Sputtering of YBCO Thin Films for Microwave Device Applications

  4. Kansas State University

    SciTech Connect

    Gray, T.; Carnes, K.; Needham, V.

    1995-08-01

    Argonne has fabricated the niobium resonators and some other linac components required for the superconducting accel/decel linac now in operation at Kansas State University. Several staff members from KSU spent a substantial period of time at ANL during FY 1985 in order to learn the technology, and they return occasionally to assemble and test the resonators. There is a continuing interchange of technical information between ANL and KSU related to linac operations, tuning, and resonator maintenance.

  5. Reasons of state

    SciTech Connect

    Moore, M.

    1993-05-01

    This editor's note is concerned with historical aspects of the Soviet Union's nuclear weapons program. Noted in the article is the viewpoint of Yuli Khariton, who has been speaking out lately in an attempt to set the record straight regarding the early years of the weapons program. Stories told by Andrei Sakharov are included to ultimately make the point that history teaches many lessons, not the least of which is that many crimes are committed by reasons of state.

  6. Models of multiquark states

    SciTech Connect

    Lipkin, H.J.

    1986-01-01

    The success of simple constituent quark models in single-hardon physics and their failure in multiquark physics is discussed, emphasizing the relation between meson and baryon spectra, hidden color and the color matrix, breakup decay modes, coupled channels, and hadron-hadron interactions via flipping and tunneling of flux tubes. Model-independent predictions for possible multiquark bound states are considered and the most promising candidates suggested. A quark approach to baryon-baryon interactions is discussed.

  7. Solid State Research.

    DTIC Science & Technology

    2007-11-02

    Technology, High Speed Electronics, Microelectronics, Analog Device Technology, and Advanced Silicon Technology. Funding is provided primarily by the...Illustrations vii Table ix Introduction xi Reports on Solid State Research xiii Organization xxiii 1. QUANTUM ELECTRONICS 1 1.1 High -Power Passively...Microchemical Etching of Silicon 13 3.2 Calorimetric Measurements of Optical Materials for 193-nm Lithography 17 4. HIGH SPEED ELECTRONICS 21 4.1

  8. Pakistan: Frontline State Again?

    DTIC Science & Technology

    1995-12-01

    leader Mohammed Ali Jinnah embarked on a new strategy against Indian Congress domination stating that Islam was in danger and the congress was...A. OUTLINE OF THE STUDY ............................. 4 II. A COLD W AR W ITHIN ...................................... 9 A. LEGACY OF PARTITION ...in the region, one absolute of Indo-Pak relations remains after the end of the cold war. Since the partition of India in 1947, Pakistan has been

  9. Tunable solid state lasers

    SciTech Connect

    Hammerling, R.; Budgor, A.B.; Pinto, A.

    1985-01-01

    This book presents the papers given at a conference on solid state lasers. Topics considered at the conference included transition-metal-doped lasers, line-narrowed alexandrite lasers, NASA specification, meteorological lidars, laser materials spectroscopy, laser pumped single pass gain, vibronic laser materials growth, crystal growth methods, vibronic laser theory, cross-fertilization through interdisciplinary fields, and laser action of color centers in diamonds.

  10. Solid State Research

    DTIC Science & Technology

    1986-11-15

    Uttaro, R.S. Vera , A. Wilde, R.E. Young, E.M. * Research Assistant T Staff Associate t Part Time XXVI 1.1 1. SOLID STATE DEVICE RESEARCH A...substrate temperature of 850° C, as shown in Figure 3-7(b). Figure 3-8 shows the low-temperature PL spectra of an Alo 2gGao 72AS layer excited by an Ar-ion

  11. Triggers of State Failure

    DTIC Science & Technology

    2010-03-01

    insufficiently advanced for precise tipping points to be provided. It is not yet correct to suggest that if GDP falls by X amount in a single year, if...instability (described below). Some indicators will almost always denote impending state failure, such as rapidly decreasing GDP per capita, or an even...expectancy, caloric intake, democracy, GDP per capita, religious diversity and ethnic diversity. The dependent variable is the occurrence of conflict

  12. Globalization and State Soverignty

    DTIC Science & Technology

    2007-11-02

    Grahame Thompson, Globalization in Question , (Macitutious, Polity Press, 2000, 2nd edition), 256-257. Islam, M. Monwarul., “Globalization and Future of... in Question , (Macitutious, Polity Press, 2000, 2nd edition), 256-257. 8 Martin Wolf, “Will the Nation State Survive Globalization?” Foreign Affairs...Among Many?” Interview with Lebel France- January 2000; available from <http://www.france.diplomatie.fr. 7 Paul Hirst and Grahame Thompson, Globalization

  13. State summaries: Ohio

    USGS Publications Warehouse

    Wolfe, M.E.

    2006-01-01

    In 2005, the value of coal and industrial minerals sold in Ohio amounted to $1.5 billion, an increase of 7% from 2004. Coal production for the year increased 4.7% from 2004, totalling 22.3 Mt. Aggregate production totalled 114 Mt, a 4% decrease from 2004. In 2005, the state's salt sales amounted to $132 million. Production of industrial sandstone and conglomerate as well as dimension stone and limestone also increased.

  14. JWL Equation of State

    SciTech Connect

    Menikoff, Ralph

    2015-12-15

    The JWL equation of state (EOS) is frequently used for the products (and sometimes reactants) of a high explosive (HE). Here we review and systematically derive important properties. The JWL EOS is of the Mie-Grueneisen form with a constant Grueneisen coefficient and a constants specific heat. It is thermodynamically consistent to specify the temperature at a reference state. However, increasing the reference state temperature restricts the EOS domain in the (V, e)-plane of phase space. The restrictions are due to the conditions that P ≥ 0, T ≥ 0, and the isothermal bulk modulus is positive. Typically, this limits the low temperature regime in expansion. The domain restrictions can result in the P-T equilibrium EOS of a partly burned HE failing to have a solution in some cases. For application to HE, the heat of detonation is discussed. Example JWL parameters for an HE, both products and reactions, are used to illustrate the restrictions on the domain of the EOS.

  15. Coherent states on spheres

    NASA Astrophysics Data System (ADS)

    Hall, Brian C.; Mitchell, Jeffrey J.

    2002-03-01

    We describe a family of coherent states and an associated resolution of the identity for a quantum particle whose classical configuration space is the d-dimensional sphere Sd. The coherent states are labeled by points in the associated phase space T*(Sd). These coherent states are not of Perelomov type but rather are constructed as the eigenvectors of suitably defined annihilation operators. We describe as well the Segal-Bargmann representation for the system, the associated unitary Segal-Bargmann transform, and a natural inversion formula. Although many of these results are in principle special cases of the results of Hall and Stenzel, we give here a substantially different description based on ideas of Thiemann and of Kowalski and Rembieliński. All of these results can be generalized to a system whose configuration space is an arbitrary compact symmetric space. We focus on the sphere case in order to carry out the calculations in a self-contained and explicit way.

  16. The State of Adult Education

    ERIC Educational Resources Information Center

    Fleming, Ted

    2004-01-01

    In this paper, the author looks at the state of adult education in Ireland. He is suggesting that the state here means both the condition in which one now finds adult education and the role of the Irish State in adult education. He briefly outlines some recent developments in adult education, makes some critical comments on the state of adult…

  17. Quantum properties of exponential states

    SciTech Connect

    Luis, Alfredo

    2007-05-15

    The use of Renyi entropy as an uncertainty measure alternative to variance leads to the study of states with quantum fluctuations below the levels established by Gaussian states, which are the position-momentum minimum uncertainty states according to variance. We examine the quantum properties of states with exponential wave functions, which combine reduced fluctuations with practical feasibility.

  18. Common Core State Standards 101

    ERIC Educational Resources Information Center

    Rothman, Robert

    2013-01-01

    The Common Core State Standards (CCSS) represent the first time that nearly every state has set common expectations for what students should know and be able to do. In the past, each state set its own standards, and the results varied widely. And while states collectively developed these common standards, decisions about the curriculum and…

  19. State Intervention in Higher Education.

    ERIC Educational Resources Information Center

    Glenny, Lyman A.; Bowen, Frank M.

    State intervention in higher education is discussed, and state and federal regulations that affect higher education are discussed and contrasted. The structures and procedures by which states intervene in higher education are outlined, and the issue of institutional autonomy is considered. Policy areas through which the state can affect higher…

  20. Michigan: The Great Lakes State

    ERIC Educational Resources Information Center

    McKay, Sandra Lee; La Luzerne-Oi, Sally

    2009-01-01

    Although Michigan is often called the "Wolverine State," its more common nickname is the "Great Lakes State." This name comes from the fact that Michigan is the only state in the United States that borders four of the five Great Lakes. Also referred to as the "Water Wonderland," Michigan has 11,000 additional lakes,…

  1. Orbital State Uncertainty Realism

    NASA Astrophysics Data System (ADS)

    Horwood, J.; Poore, A. B.

    2012-09-01

    Fundamental to the success of the space situational awareness (SSA) mission is the rigorous inclusion of uncertainty in the space surveillance network. The *proper characterization of uncertainty* in the orbital state of a space object is a common requirement to many SSA functions including tracking and data association, resolution of uncorrelated tracks (UCTs), conjunction analysis and probability of collision, sensor resource management, and anomaly detection. While tracking environments, such as air and missile defense, make extensive use of Gaussian and local linearity assumptions within algorithms for uncertainty management, space surveillance is inherently different due to long time gaps between updates, high misdetection rates, nonlinear and non-conservative dynamics, and non-Gaussian phenomena. The latter implies that "covariance realism" is not always sufficient. SSA also requires "uncertainty realism"; the proper characterization of both the state and covariance and all non-zero higher-order cumulants. In other words, a proper characterization of a space object's full state *probability density function (PDF)* is required. In order to provide a more statistically rigorous treatment of uncertainty in the space surveillance tracking environment and to better support the aforementioned SSA functions, a new class of multivariate PDFs are formulated which more accurately characterize the uncertainty of a space object's state or orbit. The new distribution contains a parameter set controlling the higher-order cumulants which gives the level sets a distinctive "banana" or "boomerang" shape and degenerates to a Gaussian in a suitable limit. Using the new class of PDFs within the general Bayesian nonlinear filter, the resulting filter prediction step (i.e., uncertainty propagation) is shown to have the *same computational cost as the traditional unscented Kalman filter* with the former able to maintain a proper characterization of the uncertainty for up to *ten

  2. Attosecond Time-Resolved Autoionization of Argon

    SciTech Connect

    Wang He; Chini, Michael; Chen Shouyuan; Zhang Changhua; Cheng Yan; Wu Yi; Thumm, Uwe; He Feng; Chang Zenghu

    2010-10-01

    Autoionization of argon atoms was studied experimentally by transient absorption spectroscopy with isolated attosecond pulses. The peak position, intensity, linewidth, and shape of the 3s3p{sup 6}np {sup 1}P Fano resonance series (26.6-29.2 eV) were modified by intense few-cycle near infrared laser pulses, while the delay between the attosecond pulse and the laser pulse was changed by a few femtoseconds. Numerical simulations revealed that the experimentally observed splitting of the 3s3p{sup 6}4p {sup 1}P line is caused by the coupling between two short-lived highly excited states in the strong laser field.

  3. Transition States and transition state analogue interactions with enzymes.

    PubMed

    Schramm, Vern L

    2015-04-21

    Enzymatic transition states have lifetimes of a few femtoseconds (fs). Computational analysis of enzyme motions leading to transition state formation suggests that local catalytic site motions on the fs time scale provide the mechanism to locate transition states. An experimental test of protein fs motion and its relation to transition state formation can be provided by isotopically heavy proteins. Heavy enzymes have predictable mass-altered bond vibration states without altered electrostatic properties, according to the Born-Oppenheimer approximation. On-enzyme chemistry is slowed in most heavy proteins, consistent with altered protein bond frequencies slowing the search for the transition state. In other heavy enzymes, structural changes involved in reactant binding and release are also influenced. Slow protein motions associated with substrate binding and catalytic site preorganization are essential to allow the subsequent fs motions to locate the transition state and to facilitate the efficient release of products. In the catalytically competent geometry, local groups move in stochastic atomic motion on the fs time scale, within transition state-accessible conformations created by slower protein motions. The fs time scale for the transition state motions does not permit thermodynamic equilibrium between the transition state and stable enzyme states. Isotopically heavy enzymes provide a diagnostic tool for fast coupled protein motions to transition state formation and mass-dependent conformational changes. The binding of transition state analogue inhibitors is the opposite in catalytic time scale to formation of the transition state but is related by similar geometries of the enzyme-transition state and enzyme-inhibitor interactions. While enzymatic transition states have lifetimes as short as 10(-15) s, transition state analogues can bind tightly to enzymes with release rates greater than 10(3) s. Tight-binding transition state analogues stabilize the rare but

  4. A search for equilibrium states

    NASA Technical Reports Server (NTRS)

    Zeleznik, F. J.

    1982-01-01

    An efficient search algorithm is described for the location of equilibrium states in a search set of states which differ from one another only by the choice of pure phases. The algorithm has three important characteristics: (1) it ignores states which have little prospect for being an improved approximation to the true equilibrium state; (2) it avoids states which lead to singular iteration equations; (3) it furnishes a search history which can provide clues to alternative search paths.

  5. State Energy Program Operations Manual

    SciTech Connect

    Office of Building Technology, State and Community Programs

    1999-03-17

    The State Energy Program Operations Manual is a reference tool for the states and the program officials at the U.S. Department of Energy's Office of Building Technology, State and Community Programs and Regional Support Offices as well as State Energy Offices. The Manual contains information needed to apply for and administer the State Energy Program, including program history, application rules and requirements, and program administration and monitoring requirements.

  6. State Clean Energy Policies Analysis (SCEPA): State Tax Incentives

    SciTech Connect

    Lantz, E.; Doris, E.

    2009-10-01

    As a policy tool, state tax incentives can be structured to help states meet clean energy goals. Policymakers often use state tax incentives in concert with state and federal policies to support renewable energy deployment or reduce market barriers. This analysis used case studies of four states to assess the contributions of state tax incentives to the development of renewable energy markets. State tax incentives that are appropriately paired with complementary state and federal policies generally provide viable mechanisms to support renewable energy deployment. However, challenges to successful implementation of state tax incentives include serving project owners with limited state tax liability, assessing appropriate incentive levels, and differentiating levels of incentives for technologies with different costs. Additionally, state tax incentives may result in moderately higher federal tax burdens. These challenges notwithstanding, state tax incentives that consider certain policy design characteristics can support renewable energy markets and state clean energy goals.The scale of their impact though is directly related to the degree to which they support the renewable energy markets for targeted sectors and technologies. This report highlights important policy design considerations for policymakers using state tax incentives to meet clean energy goals.

  7. GLSEN's State of the States: How One Seattle Educator Gets an "A" in a Failing State

    ERIC Educational Resources Information Center

    Vaught, Sabina Elena

    2005-01-01

    The Gay, Lesbian and Straight Education Network's (GLSEN) report "State of the States: A policy analysis of lesbian, gay, bisexual and transgender (LGBT) safer schools issues" presents a thorough and comprehensive analysis of the 50 states and the District of Columbia. State grading is based on five categories, which include the…

  8. Semiclassical framed BPS states

    NASA Astrophysics Data System (ADS)

    Moore, Gregory W.; Royston, Andrew B.; Van den Bleeken, Dieter

    2016-07-01

    We provide a semiclassical description of framed BPS states in four-dimensional {N}=2 super Yang-Mills theories probed by 't Hooft defects, in terms of a supersymmetric quantum mechanics on the moduli space of singular monopoles. Framed BPS states, like their ordinary counterparts in the theory without defects, are associated with the L 2 kernel of certain Dirac operators on moduli space, or equivalently with the L 2 cohomology of related Dolbeault operators. The Dirac/Dolbeault operators depend on two Cartan-valued Higgs vevs. We conjecture a map between these vevs and the Seiberg-Witten special coordinates, consistent with a one-loop analysis and checked in examples. The map incorporates all perturbative and nonperturbative corrections that are relevant for the semiclassical construction of BPS states, over a suitably defined weak coupling regime of the Coulomb branch. We use this map to translate wall crossing formulae and the no-exotics theorem to statements about the Dirac/Dolbeault operators. The no-exotics theorem, concerning the absence of nontrivial SU(2) R representations in the BPS spectrum, implies that the kernel of the Dirac operator is chiral, and further translates into a statement that all L 2 cohomology of the Dolbeault operator is concentrated in the middle degree. Wall crossing formulae lead to detailed predictions for where the Dirac operators fail to be Fredholm and how their kernels jump. We explore these predictions in nontrivial examples. This paper explains the background and arguments behind the results announced in the short note [1].

  9. Steady state thermal radiometers

    NASA Technical Reports Server (NTRS)

    Loose, J. D. (Inventor)

    1974-01-01

    A radiometer is described operating in a vacuum under steady state conditions. The front element is an aluminum sheet painted on the outer side with black or other absorptive material of selected characteristics. A thermocouple is bonded to the inner side of the aluminum sheet. That is backed by highly insulative layers of glass fiber and crinkled, aluminized Mylar polyester. Those layers are backed with a sturdy, polyester sheet, and the entire lamination is laced together by nylon cords. The device is highly reliable in that it does not drift out of calibration, and is significantly inexpensive.

  10. Solid State Research

    DTIC Science & Technology

    1992-05-15

    L. Chang, T. C. McGill* E. E. Mendez, and C. Tejedor , C. D. Parker eds. (Plenum, New York, 1991), W. D. Goodhue p. 487 Free-Space Board-to-Board...International Solid- Limits and Applications in Fast M. A. Hollis State Circuits Conference, Logic Circuits F . W. Smith San Francisco, California, 19-21...for 193-nm D. C. Shaver Lithography Process Development D. M. Craig C. A. Marchi M. A. Hartney F . Goodall* Optical Lithography at Feature Sizes M. A

  11. Solid State Research.

    DTIC Science & Technology

    2007-11-02

    Functionality Process Accuracy CCD MDAC 25,000 Multiply/add 2-Poly-Si, 2-metal 1.2 /zm Analog x 8 b Digital CMOS [1] 2,300 Multiply/add 2-Poly...additional support provided by the Army, ARPA, Navy, BMDO, NASA, and NIST. in TABLE OF CONTENTS Abstract üi List of Illustrations yii List of Tables x ...Introduction x * Reports on Solid State Research xiii Organization xxm 1. ELECTROOPTICAL DEVICES 1 1.1 1.3-jUm Strained-Layer InGaAsP/InP Quantum

  12. Solid state optical microscope

    SciTech Connect

    Young, Ian T.

    1983-01-01

    A solid state optical microscope wherein wide-field and high-resolution images of an object are produced at a rapid rate by utilizing conventional optics with a charge-coupled photodiode array. A galvanometer scanning mirror, for scanning in one of two orthogonal directions is provided, while the charge-coupled photodiode array scans in the other orthogonal direction. Illumination light from the object is incident upon the photodiodes, creating packets of electrons (signals) which are representative of the illuminated object. The signals are then processed, stored in a memory, and finally displayed as a video signal.

  13. Solid state optical microscope

    DOEpatents

    Young, I.T.

    1983-08-09

    A solid state optical microscope wherein wide-field and high-resolution images of an object are produced at a rapid rate by utilizing conventional optics with a charge-coupled photodiode array. A galvanometer scanning mirror, for scanning in one of two orthogonal directions is provided, while the charge-coupled photodiode array scans in the other orthogonal direction. Illumination light from the object is incident upon the photodiodes, creating packets of electrons (signals) which are representative of the illuminated object. The signals are then processed, stored in a memory, and finally displayed as a video signal. 2 figs.

  14. Flordia State University

    SciTech Connect

    Fox, J.; Frawley, A.; Myers, E.

    1995-08-01

    Argonne fabricated the niobium resonators and some auxiliary devices for the superconducting-linac energy booster built at Florida State University. Personnel from FSU came to ANL to assemble and test the resonators. The main resonator fabrication work for FSU was completed during 1986, but we continue to interact with personnel concerning ongoing refinements in the technology. Topics in which we were most recently involved are (1) a change in the method of cooling the FSU resonators and (2) the transfer of information about fast tuner upgrades. During the past year there was very little interaction.

  15. Correlated multipartite quantum states

    NASA Astrophysics Data System (ADS)

    Batle, J.; Casas, M.; Plastino, A.

    2013-03-01

    We investigate quantum states that possess both maximum entanglement and maximum discord between the pertinent parties. Since entanglement (discord) is defined only for bipartite (two-qubit) systems, we use an appropriate sum over all bipartitions as the associated measure. The ensuing definition—not new for entanglement—is thus extended here to quantum discord. Also, additional dimensions within the parties are considered (qudits). We also discuss quantum correlations that induce Mermin's Bell-inequality violation for all multiqubit systems. One finds some differences when quantum mechanics is defined over the field of real or of complex numbers.

  16. Differentiating among penal states.

    PubMed

    Lacey, Nicola

    2010-12-01

    This review article assesses Loïc Wacquant's contribution to debates on penality, focusing on his most recent book, Punishing the Poor: The Neoliberal Government of Social Insecurity (Wacquant 2009), while setting its argument in the context of his earlier Prisons of Poverty (1999). In particular, it draws on both historical and comparative methods to question whether Wacquant's conception of 'the penal state' is adequately differentiated for the purposes of building the explanatory account he proposes; about whether 'neo-liberalism' has, materially, the global influence which he ascribes to it; and about whether, therefore, the process of penal Americanization which he asserts in his recent writings is credible.

  17. Solid State Research

    DTIC Science & Technology

    1990-11-15

    Alo .3Gao.7As confining layers. 38 IX Figure No. Page 3-2 Schematic structure and energy diagram of AlInGaAs/AlGaAs SCH SQW diode laser. 39 3-3...Lithography Photooxidation of a-Conjugated Si-Si Network Polymers High-Power Solid-State Laser Radar Technology Heat Driven Cryocoolers for...M.J. Nichols, K.B. Parker, CD. Rabe, S. Rathman, D.D. Smith, F.W., III Vera , A. xxvn ELECTROOPTICAL DEVICES ANALOG DEVICE TECHNOLOGY R.C

  18. Solid state oxygen sensor

    DOEpatents

    Garzon, F.H.; Chung, B.W.; Raistrick, I.D.; Brosha, E.L.

    1996-08-06

    Solid state oxygen sensors are provided with a yttria-doped zirconia as an electrolyte and use the electrochemical oxygen pumping of the zirconia electrolyte. A linear relationship between oxygen concentration and the voltage arising at a current plateau occurs when oxygen accessing the electrolyte is limited by a diffusion barrier. A diffusion barrier is formed herein with a mixed electronic and oxygen ion-conducting membrane of lanthanum-containing perovskite or zirconia-containing fluorite. A heater may be used to maintain an adequate oxygen diffusion coefficient in the mixed conducting layer. 4 figs.

  19. Solid state oxygen sensor

    DOEpatents

    Garzon, Fernando H.; Chung, Brandon W.; Raistrick, Ian D.; Brosha, Eric L.

    1996-01-01

    Solid state oxygen sensors are provided with a yttria-doped zirconia as an electrolyte and use the electrochemical oxygen pumping of the zirconia electrolyte. A linear relationship between oxygen concentration and the voltage arising at a current plateau occurs when oxygen accessing the electrolyte is limited by a diffusion barrier. A diffusion barrier is formed herein with a mixed electronic and oxygen ion-conducting membrane of lanthanum-containing perovskite or zirconia-containing fluorite. A heater may be used to maintain an adequate oxygen diffusion coefficient in the mixed conducting layer.

  20. Whitner v. State.

    PubMed

    1997-11-19

    The Supreme Court of South Carolina held that a viable fetus is a child within the meaning of the state's child endangerment statute. The court defined a viable fetus as one that is capable of independent life apart from the mother. In this case, the mother had ingested crack cocaine during the third trimester of her pregnancy and was convicted of criminal child neglect by a lower court. Her petition for post-conviction relief was granted by the lower court. On appeal, the Supreme Court of South Carolina reversed the lower court's decision, rejecting, as without merit, the mother's arguments that her conviction had violated both her due process rights, and her right to privacy under the Fourteenth Amendment to the U.S. Constitution. The court ruled that the state had a compelling interest to ensure the life and health of a viable fetus. Two justices dissented, one on the grounds that the term "child" in the child endangerment statute did not apply to fetuses, and one on the grounds that the statute does not regulate the conduct of a woman toward her unborn child.

  1. Solid State Humidity Sensors

    NASA Astrophysics Data System (ADS)

    Chang, Song-Lin

    There are only a few solid state humidity sensors available today. Most of those sensors use a porous oxide material as a principal part of the device. The devices work on the basis of a change in resistance as the moisture in the air varies. In this experiment, two solid state humidity sensors have been developed for use under practical conditions. One is a Polymer Oxide Semiconductor device with a POLYOX film that absorbs the moisture from the air. The amount of water dipoles absorbed by the polymer is a function of relative humidity. This sensor can measure relative humidity from 20% to 90%. The other is a Dew Point sensor. The sensor is in contact with the upper surface of a miniature Peltier cooler. Water molecules deposited on the sensor surface cause the electrical current through the sensor to increase. The operator adjusts the temperature of the Peltier cooler until a saturated current through the sensor is reached. About one min. is required to measure low relative humidities. The Dew Point sensor can measure a range of relative humidities of 30% to 80%.

  2. State of the States: Fuel Cells in America 2015

    SciTech Connect

    Curtin, Sandra; Jennifer, Gangi

    2015-12-17

    This December 2015 report, the sixth in a series, provides a comprehensive analysis of state activities supporting fuel cell and hydrogen technology, profiles of leading states, and a catalog of recent installations, policies, funding, and deployments around the country.

  3. State IQ and suicide rates in the United States.

    PubMed

    Voracek, Martin

    2007-08-01

    Previous findings pertaining to the direction (positive or negative) of the ecological correlation between intelligence and suicide rates in the USA have been conflicting. Using novel state IQ estimates, derived from the Scholastic Assessment Test, the American College Test, these tests combined, or the National Assessment of Educational Progress state scores, these estimates were not consistently associated to state suicide rates. Whereas ACT-derived state IQ was significantly positively correlated with suicide rates, the correlation with composite ACT-SAT-derived state IQ was significantly negative and with both SAT-derived and NAEP-derived state IQ also negative but not significant. Validity checks pointed to possible methodological problems with the state IQ estimates. Currently available estimates of state IQ, therefore, seem not appropriate to resolve the question of the direction of the ecological correlation of intelligence and suicide mortality across the USA.

  4. State Energy Alternatives: Alternative Energy Resources by State

    DOE Data Explorer

    This U.S. map provides state by state information on incentives and laws related to alternative fuels and advanced vehicles. Discover what's available in each state for innovation grants, infrastructure grants, and production grants and who to contact. Find out how many alternative refueling stations are available in each state and where they are. Tennessee, for example, in 2009, has 114 alternative refueling stations: 36 biodiesel, 1 electrical, 29 ethanol, 4 natural gas, and 44 propane. There are also 5 Truck Stop Electrification (TSE) sites in Tennessee. Users can also find out from this map interface the contacts for Clean Cities in a state, information about renewable energy projects and activities in each state, fuel prices across a state, and biomass potential resources and current production in each state.

  5. States' Progress and Challenges in Implementing Common Core State Standards

    ERIC Educational Resources Information Center

    Kober, Nancy; Rentmer, Diane Stark

    2011-01-01

    Most states are participating in the initiative led by the National Governors Association and the Council of Chief State School Officers to develop and adopt voluntary common core state standards that will outline what elementary and secondary school students are expected to learn in English language arts and mathematics. Implementing these…

  6. State of the States: Fuel Cells in America

    SciTech Connect

    2011-06-15

    This 2011 report, written by Fuel Cells 2000 and partially funded by the U.S. Department of Energy's Fuel Cell Technologies Program, provides an update of fuel cell and hydrogen activity in the 50 states and District of Columbia. State activities reported include new policies and funding, recent and planned fuel cell and hydrogen installations, and recent activities by state industries and universities.

  7. States of Consciousness and State-Specific Sciences

    ERIC Educational Resources Information Center

    Tart, Charles T.

    1972-01-01

    Proposes the development of state-specific sciences" to overcome the problems of scientifically studying altered states of consciousness induced by drugs or meditation from the paradigm of the ordinary consciousness state. The requirements of good observation, public nature of the observation, logical theorizing, and testing of theories by…

  8. State Action: Judicial Perpetuation of the State/Private Distinction

    ERIC Educational Resources Information Center

    Antoun, Frederick G., Jr.

    1975-01-01

    Various state action theories are examined as they have been applied to activate fourteenth amendment strictures. Two broad categories are analyzed: (1) cases in which the degree of state involvement in private activity has satisfied the state action requirement, and (2) cases in which private actors have assumed a "public function." (LBH)

  9. State Action: Judicial Perpetuation of the State/Private Distinction

    ERIC Educational Resources Information Center

    Antoun, Frederick G., Jr.

    1975-01-01

    The "state action" concept broadens the Fourteenth Amendment to restrict certain objectionable private activity. In an effort to clarify the requirement of state action as it has been interpreted and applied by the Supreme Court, the author examines the various state action theories as they have been applied to activate Fourteenth Amendment…

  10. Toward State Tax Reform: Lessons from State Tax Studies.

    ERIC Educational Resources Information Center

    McGuire, Therese J.; Rio, Jessica E.

    This paper reviews recent state tax-commission recommendations in selected states and identifies critical factors for the success of state tax-reform commissions. The paper focuses on factors linked to the process of forming a commission and generating the necessary consensus to enact tough reforms. It describes and compares comprehensive studies…

  11. Governors' Top Education Issues: State of the States 2014

    ERIC Educational Resources Information Center

    Thomsen, Jennifer

    2014-01-01

    Education issues were again at the forefront when the leaders of 42 states and the District of Columbia outlined their priorities in their 2014 State of the State addresses. Governors outlined their plans for increasing the quality and availability of education--from preschool through postsecondary--to spur economic growth and enhance the quality…

  12. When Distance Education Crosses State Boundaries: Western States' Policies. 1995.

    ERIC Educational Resources Information Center

    Western Interstate Commission for Higher Education, Boulder, CO. Western Cooperative for Educational Communications.

    This report summarizes western states' policies and regulations governing the approval of higher education programs electronically delivered across state lines by institutions in other states. It caps the first year's activities in a 3-year Western Cooperative for Educational Telecommunications project, "Balancing Quality and Access: Reducing…

  13. State Homeschool Policies: A Patchwork of Provisions. 50-State Reviews

    ERIC Educational Resources Information Center

    Wixom, Micah Ann

    2015-01-01

    In the absence of federal homeschooling guidelines, states regulate homeschooling through a patchwork of provisions. Homeschooling policies vary widely from one state to the next and families' homeschooling experiences will likely be very different depending on where they live. For example, some states have little or no homeschooling…

  14. An Overview of the 2015 State of the States

    ERIC Educational Resources Information Center

    Weiler, Spencer C.; Hartman, William

    2015-01-01

    In February 2015 a large group of scholars, researchers, and practitioners interested in P-20 finance issues gathered in St. Louis, Missouri, for the National Education Finance Academy's annual conference, on February 25-27, 2015 to discuss, among multiple topics, the state of P-20 finance in all 50 states. There were 35 states represented in the…

  15. State Leadership for School Improvement: An Analysis of Three States

    ERIC Educational Resources Information Center

    Louis, Karen Seashore; Thomas, Emanda; Gordon, Molly F.; Febey, Karen S.

    2008-01-01

    Purpose: Extant reports on states' policy differences are mostly descriptive and largely ignore the pervasive role of political culture on their educational policy-making processes. This article examines the effect of policy culture on states' policy-making mechanisms. There is evidence that a state's political culture is a significant mediating…

  16. Evaluating State Principal Evaluation Plans across the United States

    ERIC Educational Resources Information Center

    Fuller, Edward J.; Hollingworth, Liz; Liu, Jing

    2015-01-01

    Recent federal legislation has created strong incentives for states to adopt principal evaluation systems, many of which include new measures of principal effectiveness such as estimates of student growth and changes in school climate. Yet, there has been little research on principal evaluation systems and no state-by-state analysis of the…

  17. Teaching Kansas History: The State of the State.

    ERIC Educational Resources Information Center

    Isern, Thomas D.

    1990-01-01

    Provides a history of debate concerning issue of teaching Kansas state history in public schools as mandated by law. Studies show the failure to comply was a result of nonavailability of textbooks and lack of teacher preparation. Contends that State Department of Education did not support the law because state history is not taught in many Kansas…

  18. Barrett v. United States.

    PubMed

    1985-10-08

    In considering a suit brought against the U.S. government and other officials arising from the 1953 death of a civilian who unknowingly served as a subject for an Army chemical warfare experiment, the U.S. District Court for the Southern District of New York dismissed some claims and permitted the rest to proceed to trial. The victim, while a patient at the New York State Psychiatric Institute, had been injected with a mescaline derivative to determine the effects of psychoactive drugs on psychiatric behavior. The victim's daughter was not barred by an earlier settlement of the case in 1955 or by the statute of limitations from continuing to press the lawsuit, as additional information had since surfaced concerning conspiracy and fraudulent actions by the defendants in the earlier proceeding.

  19. Solid state rapid thermocycling

    DOEpatents

    Beer, Neil Reginald; Spadaccini, Christopher

    2014-05-13

    The rapid thermal cycling of a material is targeted. A solid state heat exchanger with a first well and second well is coupled to a power module. A thermoelectric element is coupled to the first well, the second well, and the power module, is configured to transfer thermal energy from the first well to the second well when current from the power module flows through the thermoelectric element in a first direction, and is configured to transfer thermal energy from the second well to the first well when current from the power module flows through the thermoelectric element in a second direction. A controller may be coupled to the thermoelectric elements, and may switch the direction of current flowing through the thermoelectric element in response to a determination by sensors coupled to the wells that the amount of thermal energy in the wells falls below or exceeds a pre-determined threshold.

  20. Solid state power controllers

    NASA Technical Reports Server (NTRS)

    Gibbs, R. S.

    1973-01-01

    The rationale, analysis, design, breadboarding and testing of the incremental functional requirements are reported that led to the development of prototype 1 and 5 Amp dc and 1 Amp ac solid state power controllers (SSPC's). The SSPC's are to be considered for use as a replacement of electro-mechanical relays and circuit breakers in future spacecraft and aircraft. They satisfy the combined function of both the relay and circuit breaker and can be remotely controlled by small signals, typically 10 mA, 5 to 28 Vdc. They have the advantage over conventional relay/circuit breaker systems in that they can be located near utilization equipment and the primary ac or dc bus. The low level control, trip indication and status signals can be circuited by small guage wire for control, computer interface, logic, electrical multiplexing, unboard testing, and power management and distribution purposes. This results in increased system versatility at appreciable weight saving and increased reliability.

  1. Weather and emotional state

    NASA Astrophysics Data System (ADS)

    Spasova, Z.

    2010-09-01

    Introduction Given the proven effects of weather on the human organism, an attempt to examine its effects on a psychic and emotional level has been made. Emotions affect the bio-tonus, working ability and concentration, hence their significance in various domains of economic life, such as health care, education, transportation, tourism, etc. Data and methods The research has been made in Sofia City within a period of 8 months, using 5 psychological methods (Eysenck Personality Questionnaire (EPQ), State-Trait Anxiety Inventory (STAI), Test for Self-assessment of the emotional state (developed by Wessman and Ricks), Test for evaluation of moods and Test "Self-confidence - Activity - Mood" (developed by the specialists from the Military Academy in Saint Petersburg). The Fiodorov-Chubukov's complex-climatic method was used to characterize meteorological conditions because of the purpose to include in the analysis a maximal number of meteorological elements. 16 weather types are defined in dependence of the meteorological elements values according to this method. Abrupt weather changes from one day to another, defined by the same method, were considered as well. Results and discussions The results obtained by t-test show that the different categories of weather lead to changes in the emotional status, which indicates a character either positive or negative for the organism. The abrupt weather changes, according to expectations, have negative effect on human emotions but only when a transition to the cloudy weather or weather type, classified as "unfavourable" has been realized. The relationship between weather and human emotions is rather complicated since it depends on individual characteristics of people. One of these individual psychological characteristics, marked by the dimension "neuroticism", has a strong effect on emotional reactions in different weather conditions. Emotionally stable individuals are more "protected" to the weather influence on their emotions

  2. Realizing Controllable Quantum States

    NASA Astrophysics Data System (ADS)

    Takayanagi, Hideaki; Nitta, Junsaku

    1. Entanglement in solid states. Orbital entanglement and violation of bell inequalities in mesoscopic conductors / M. Büttiker, P. Samuelsson and E. V. Sukhoruk. Teleportation of electron spins with normal and superconducting dots / O. Sauret, D. Feinberg and T. Martin. Entangled state analysis for one-dimensional quantum spin system: singularity at critical point / A. Kawaguchi and K. Shimizu. Detecting crossed Andreev reflection by cross-current correlations / G. Bignon et al. Current correlations and transmission probabilities for a Y-shaped diffusive conductor / S. K. Yip -- 2. Mesoscopic electronics. Quantum bistability, structural transformation, and spontaneous persistent currents in mesoscopic Aharonov-Bohm loops / I. O. Kulik. Many-body effects on tunneling of electrons in magnetic-field-induced quasi one-dimensional systems in quantum wells / T. Kubo and Y. Tokura. Electron transport in 2DEG narrow channel under gradient magnetic field / M. Hara et al. Transport properties of a quantum wire with a side-coupled quantum dot / M. Yamaguchi et al. Photoconductivity- and magneto-transport studies of single InAs quantum wires / A. Wirthmann et al. Thermoelectric transports in charge-density-wave systems / H. Yoshimoto and S. Kurihara -- 3. Mesoscopic superconductivity. Parity-restricted persistent currents in SNS nanorings / A. D. Zaikin and S. V. Sharov. Large energy dependence of current noise in superconductingh/normal metal junctions / F. Pistolesi and M. Houzet. Generation of photon number states and their superpositions using a superconducting qubit in a microcavity / Yu-Xi Liu, L. F. Wei and F. Nori. Andreev interferometry for pumped currents / F. Taddei, M. Governale and R. Fazio. Suppression of Cooper-pair breaking against high magnetic fields in carbon nanotubes / J. Haruyama et al. Impact of the transport supercurrent on the Josephson effect / S. N. Shevchenko. Josephson current through spin-polarized Luttinger liquid / N. Yokoshi and S. Kurihara

  3. Updated Principle of Corresponding States

    ERIC Educational Resources Information Center

    Ben-Amotz, Dor; Gift, Alan D.; Levine, R. D.

    2004-01-01

    The rule of corresponding states, which shows the connection between the thermodynamic properties of various liquids is re-examined. The overall likeness is observed by using an updated scaling technique of Lennard-Jones corresponding states (LJ-CS).

  4. Breast Cancer Rates by State

    MedlinePlus

    ... Associated Lung Ovarian Prostate Skin Uterine Cancer Home Breast Cancer Rates by State Language: English Español (Spanish) Recommend ... from breast cancer each year. Rates of Getting Breast Cancer by State The number of people who get ...

  5. Lung Cancer Rates by State

    MedlinePlus

    ... HPV-Associated Ovarian Prostate Skin Uterine Cancer Home Lung Cancer Rates by State Language: English Español (Spanish) ... incidence data are currently available. Rates of Getting Lung Cancer by State The number of people who ...

  6. State of the States. Fuel Cells in America 2012

    SciTech Connect

    Curtin, Sandra; Gangi, Jennifer; Skukowski, Ryan

    2012-09-01

    This report, written by Fuel Cells 2000 and partially funded by the U.S. Department of Energy's Fuel Cell Technologies Program, continues to build on the April 2010 State of the States report that provided a snapshot of fuel cell and hydrogen activity in the 50 states and District of Columbia. This update report provides more details on the progress and activities that happened since the second report, issued in June 2011. Details reported for each state include new policies and funding, recent and planned fuel cell and hydrogen installations, and recent activity by state industry and universities.

  7. Graphene on weakly interacting metals: Dirac states versus surface states

    NASA Astrophysics Data System (ADS)

    Jolie, Wouter; Craes, Fabian; Busse, Carsten

    2015-03-01

    We investigate the interplay between graphene and different, weakly interacting metal substrates by measuring the local density of states of the surface with scanning tunneling spectroscopy. Energy-resolved Friedel oscillations, confined states, and a prominent signal in point spectra are found after intercalating several monolayers of silver between graphene and Ir(111) and correspond to the shifted surface state of silver. These features outweigh spectroscopic signatures of graphene, which are retrieved when the amount of silver is reduced to one monolayer. Hence, suppressing the surface states of the metal substrate enhances the sensitivity to the Dirac states of quasi-free-standing graphene.

  8. Optimal joint remote state preparation of equatorial states

    NASA Astrophysics Data System (ADS)

    Li, Xihan; Ghose, Shohini

    2015-12-01

    We present a scheme for optimal joint remote state preparation of two-qubit equatorial states. Our protocol improves on a previous scheme (Choudhury and Dhara in Quantum Inf Process 14:373-379, 2015) that had a success probability of 25 %, which increased to 50 % when extra classical information is sent to the receiver. We show that using our modified scheme, the desired state can be prepared deterministically with the same quantum channel. Moreover, we generalize the scheme to prepare N-qubit equatorial states in which the receiver can reconstruct the original state with 100 % success probability.

  9. Supercoherent states and physical systems

    SciTech Connect

    Fatyga, B.W.; Kostelecky, V.A. . Dept. of Physics); Nieto, M.M. ); Truax, D.R. . Dept. of Chemistry)

    1991-01-01

    A method is developed for obtaining coherent states of a system admitting a supersymmetry. These states are called supercoherent states. The approach presented in this talk is based on an extension to supergroups of the usual group-theoretic approach. The example of the supersymmetric harmonic oscillator is discussed, thereby illustrating some of the attractive features of the method. Supercoherent states of an electron moving in a constant magnetic field are also described. 35 refs.

  10. Supercoherent states and physical systems

    NASA Technical Reports Server (NTRS)

    Fatyga, B. W.; Kostelecky, V. Alan; Nieto, Michael Martin; Truax, D. Rodney

    1992-01-01

    A method is developed for obtaining coherent states of a system admitting a supersymmetry. These states are called supercoherent states. The presented approach is based on an extension to supergroups of the usual group-theoretic approach. The example of the supersymmetric harmonic oscillator is discussed, thereby illustrating some of the attractive features of the method. Supercoherent states of an electron moving in a constant magnetic field are also described.

  11. Academic Accountability and State Intervention.

    ERIC Educational Resources Information Center

    Duncan, John W.

    This speech discusses the national emerging trend toward state intervention in local educational processes as part of the academic accountability movement. It provides examples of reforms and improvements whereby state intervention furnished local school improvement. The address focuses on state intervention in Jersey City, New Jersey; predicts…

  12. States Trend toward Performance Funding

    ERIC Educational Resources Information Center

    Hermes, Jim

    2012-01-01

    As college completion becomes a priority, more state legislatures are challenging community colleges to demonstrate progress by tying funding measures to institutional performance. Tom Harnisch, a policy analyst with the American Association of State Colleges and Universities, reports that 17 states are currently implementing or considering the…

  13. Configurational entropy of glueball states

    NASA Astrophysics Data System (ADS)

    Bernardini, Alex E.; Braga, Nelson R. F.; da Rocha, Roldão

    2017-02-01

    The configurational entropy of glueball states is calculated using a holographic description. Glueball states are represented by a supergravity dual picture, consisting of a 5-dimensional graviton-dilaton action of a dynamical holographic AdS/QCD model. The configurational entropy is studied as a function of the glueball spin and of the mass, providing information about the stability of the glueball states.

  14. State Definitions of Emotional Disturbance

    ERIC Educational Resources Information Center

    Wery, Jessica J.; Cullinan, Douglas

    2013-01-01

    This article examines definitions state education agencies use to describe the federal education disability called "emotional disturbance." State definitions were collected so that various aspects of them could be analyzed and compared with results of similar studies completed in the 1970s and 1980s. Among results are that state definitions have…

  15. Deceptive Business Practices: State Regulations.

    ERIC Educational Resources Information Center

    Rohrer, Daniel Morgan

    Although much has been done at the federal level to control deceptive advertising practices, many states have no criminal laws designed to regulate advertising, and several states recently repealed such laws. This paper examines states' efforts to balance the advertiser's freedom of speech with the consumer's need for information about products by…

  16. State University System of Florida

    ERIC Educational Resources Information Center

    Board of Governors, State University System of Florida, 2012

    2012-01-01

    This paper presents some information about the State University System of Florida. The following are presented in this paper: (1) University Work Plans and Annual Reports; (2) State University System 2009 Annual Report; (3) Quick Facts: Planned New Degree Programs--2010 to 2013; (4) State University System Tuition Differential Summary, FY…

  17. Penn State DOE GATE Program

    SciTech Connect

    Anstrom, Joel

    2012-08-31

    The Graduate Automotive Technology Education (GATE) Program at The Pennsylvania State University (Penn State) was established in October 1998 pursuant to an award from the U.S. Department of Energy (U.S. DOE). The focus area of the Penn State GATE Program is advanced energy storage systems for electric and hybrid vehicles.

  18. Rodriguez: The State Courts Respond.

    ERIC Educational Resources Information Center

    Long, David C.

    1983-01-01

    Summarizes 16 state court decisions in 15 states concerning equity in statewide school finance systems, in the aftermath of the Supreme Court's San Antonio Independent School District v. Rodriguez" decision. Finds that some state legislatures and courts reformed their finance systems, while others let inequalities continue. (RW)

  19. Packaging of solid state devices

    DOEpatents

    Glidden, Steven C.; Sanders, Howard D.

    2006-01-03

    A package for one or more solid state devices in a single module that allows for operation at high voltage, high current, or both high voltage and high current. Low thermal resistance between the solid state devices and an exterior of the package and matched coefficient of thermal expansion between the solid state devices and the materials used in packaging enables high power operation. The solid state devices are soldered between two layers of ceramic with metal traces that interconnect the devices and external contacts. This approach provides a simple method for assembling and encapsulating high power solid state devices.

  20. Optimal broadcasting of mixed states

    SciTech Connect

    Dang Guifang; Fan Heng

    2007-08-15

    The N to M (M{>=}N) universal quantum broadcasting of mixed states {rho}{sup xN} is proposed for a qubit system. The broadcasting of mixed states is universal and optimal in the sense that the shrinking factor is independent of the input state and achieves the upper bound. The quantum broadcasting of mixed qubits is a generalization of the universal quantum cloning machine for identical pure input states. A pure state decomposition of the identical mixed qubits {rho}{sup xN} is obtained.

  1. State-to-state and state-to-all-states reactive scattering angular distributions: F+H /sub 2/. -->. HF+H

    SciTech Connect

    Emmons, R.W.; Suck, S.H.

    1983-04-01

    How each state-to-state reactive transition determines nonundulatory ''state-to-all-states'' angular distribution has not yet been investigated. Here we present a complete exposure of state-to-state distorted-wave Born-approximation angular distributions in order to examine how the nonoscillatory and backward-peaked state-to-all-states reactive scattering angular distribution occurs.

  2. Probabilistic cloning of equidistant states

    SciTech Connect

    Jimenez, O.; Roa, Luis; Delgado, A.

    2010-08-15

    We study the probabilistic cloning of equidistant states. These states are such that the inner product between them is a complex constant or its conjugate. Thereby, it is possible to study their cloning in a simple way. In particular, we are interested in the behavior of the cloning probability as a function of the phase of the overlap among the involved states. We show that for certain families of equidistant states Duan and Guo's cloning machine leads to cloning probabilities lower than the optimal unambiguous discrimination probability of equidistant states. We propose an alternative cloning machine whose cloning probability is higher than or equal to the optimal unambiguous discrimination probability for any family of equidistant states. Both machines achieve the same probability for equidistant states whose inner product is a positive real number.

  3. Polarized Solid State Target

    NASA Astrophysics Data System (ADS)

    Dutz, Hartmut; Goertz, Stefan; Meyer, Werner

    2017-01-01

    The polarized solid state target is an indispensable experimental tool to study single and double polarization observables at low intensity particle beams like tagged photons. It was one of the major components of the Crystal-Barrel experiment at ELSA. Besides the operation of the 'CB frozen spin target' within the experimental program of the Crystal-Barrel collaboration both collaborative groups of the D1 project, the polarized target group of the Ruhr Universität Bochum and the Bonn polarized target group, have made significant developments in the field of polarized targets within the CRC16. The Bonn polarized target group has focused its work on the development of technically challenging polarized solid target systems towards the so called '4π continuous mode polarized target' to operate them in combination with 4π-particle detection systems. In parallel, the Bochum group has developed various highly polarized deuterated target materials and high precision NMR-systems, in the meantime used for polarization experiments at CERN, JLAB and MAMI, too.

  4. Probability state modeling theory.

    PubMed

    Bagwell, C Bruce; Hunsberger, Benjamin C; Herbert, Donald J; Munson, Mark E; Hill, Beth L; Bray, Chris M; Preffer, Frederic I

    2015-07-01

    As the technology of cytometry matures, there is mounting pressure to address two major issues with data analyses. The first issue is to develop new analysis methods for high-dimensional data that can directly reveal and quantify important characteristics associated with complex cellular biology. The other issue is to replace subjective and inaccurate gating with automated methods that objectively define subpopulations and account for population overlap due to measurement uncertainty. Probability state modeling (PSM) is a technique that addresses both of these issues. The theory and important algorithms associated with PSM are presented along with simple examples and general strategies for autonomous analyses. PSM is leveraged to better understand B-cell ontogeny in bone marrow in a companion Cytometry Part B manuscript. Three short relevant videos are available in the online supporting information for both of these papers. PSM avoids the dimensionality barrier normally associated with high-dimensionality modeling by using broadened quantile functions instead of frequency functions to represent the modulation of cellular epitopes as cells differentiate. Since modeling programs ultimately minimize or maximize one or more objective functions, they are particularly amenable to automation and, therefore, represent a viable alternative to subjective and inaccurate gating approaches.

  5. Solid state laser

    NASA Technical Reports Server (NTRS)

    Rines, Glen A. (Inventor); Moulton, Peter F. (Inventor); Harrison, James (Inventor)

    1993-01-01

    A wavelength-tunable, injection-seeded, dispersion-compensated, dispersively-pumped solid state laser includes a lasing medium; a highly reflective mirror; an output coupler; at least one isosceles Brewster prism oriented to the minimum deviation angle between the medium and the mirror for directing light of different wavelengths along different paths; means for varying the angle of the highly reflective mirror relative to the light from at least one Brewster angle for selecting a predetermined laser operating wavelength; a dispersion compensation apparatus associated with the lasing medium; a laser injection seeding port disposed between the dispersion compensation apparatus and one of the mirror and coupler and including a reflective surface at an acute non-Brewster angle to the laser beam for introducing a seed input; a dispersion compensation apparatus associated with the laser medium including opposite chirality optical elements; the lasing medium including a pump surface disposed at an acute angle to the laser beam to define a discrete path for the pumping laser beam separate from the pumped laser beam.

  6. Controlled Remote State Preparation of an Arbitrary Two-Qubit State by Using GHZ States

    NASA Astrophysics Data System (ADS)

    Huang, Li; Zhao, Hong-xia

    2017-03-01

    In this paper, we demonstrate that two Greenberger-Horne-Zeilinger (GHZ) states can be used to realize the perfect and deterministic controlled remote state preparation of an arbitrary two-qubit state by performing only the two-qubit projective measurements and appropriate unitary operations.

  7. Fidelity between Gaussian mixed states with quantum state quadrature variances

    NASA Astrophysics Data System (ADS)

    Hai-Long, Zhang; Chun, Zhou; Jian-Hong, Shi; Wan-Su, Bao

    2016-04-01

    In this paper, from the original definition of fidelity in a pure state, we first give a well-defined expansion fidelity between two Gaussian mixed states. It is related to the variances of output and input states in quantum information processing. It is convenient to quantify the quantum teleportation (quantum clone) experiment since the variances of the input (output) state are measurable. Furthermore, we also give a conclusion that the fidelity of a pure input state is smaller than the fidelity of a mixed input state in the same quantum information processing. Project supported by the National Basic Research Program of China (Grant No. 2013CB338002) and the Foundation of Science and Technology on Information Assurance Laboratory (Grant No. KJ-14-001).

  8. Manipulation of electronic states and photonic states in nanosilicon

    NASA Astrophysics Data System (ADS)

    Huang, Wei-Qi; Huang, Zhong-Mei; Miao, Xin-Jian; Qin, Chao-Jian; Lv, Quan

    2014-04-01

    On different size hierarchy, period symmetry provides energy band structure, and symmetry breaking produces localized states in gap, for example nanostructures open electronic band gap by confining electrons, but defects in symmetry system produce localized electronic states in gap. The experimental results demonstrate that controlling localized states in gap by changing passivation environment can manipulate emission wavelength, such as stimulated emission at 700 nm due to oxygen passivation and enhanced electroluminescence near 1600 nm due to ytterbium passivation on nanosilicon. In same way, modulating filling fraction and period parameters in photonic crystal enlarges width of photonic band gap (PBG) by confining photons. Symmetry breaking due to defects is effective in manipulating photonic states. New applications for selecting modes in nanolaser and for building single photon source in quantum information are explored by manipulating and coupling between electronic states and photonic states.

  9. State of the States: Fuel Cells in America 2013

    SciTech Connect

    Curtin, Sandra; Gangi, Jennifer

    2013-10-31

    This October 2013 report, written by Fuel Cells 2000 and partially funded by the U.S. Department of Energy's Fuel Cell Technologies Office, continues to build on the April 2010 State of the States report that provided a snapshot of fuel cell and hydrogen activity in the 50 states and District of Columbia. This update report provides more details on the progress and activities that happened since the third report, issued in August 2012.

  10. Teleportation of entangled states without Bell-state measurement

    SciTech Connect

    Cardoso, Wesley B.; Baseia, B.; Avelar, A.T.; Almeida, N.G. de

    2005-10-15

    In a recent paper [Phys. Rev. A 70, 025803 (2004)] we presented a scheme to teleport an entanglement of zero- and one-photon states from a bimodal cavity to another one, with 100% success probability. Here, inspired by recent results in the literature, we have modified our previous proposal to teleport the same entangled state without using Bell-state measurements. For comparison, the time spent, the fidelity, and the success probability for this teleportation are considered.

  11. State of the States: Fuel Cells in America, 2010

    SciTech Connect

    Curtin, Sandra; Delmont, Elizabeth; Gangi, Jennifer

    2010-04-01

    This report, written by Fuel Cells 2000 and partially funded by the U.S. Department of Energy's Fuel Cell Technologies Program, provides a snapshot of fuel cell and hydrogen activity in the 50 states and District of Columbia. It features the top five fuel cell states (in alphabetical order): California, Connecticut, New York, Ohio, and South Carolina. State activities reported include supportive fuel cell and hydrogen policies, installations and demonstrations, road maps, and level of activism.

  12. State electronic disease surveillance systems --- United States, 2007 and 2010.

    PubMed

    2011-10-21

    The National Electronic Disease Surveillance System (NEDSS) is a web-based infrastructure for public health surveillance data exchange between CDC and the 50 states. In 2007, the Council of State and Territorial Epidemiologists (CSTE) conducted an assessment to evaluate states' electronic disease surveillance capacity. In 2010, CSTE conducted a follow-up assessment to evaluate the operational status and progress of integration, interoperability, and capacity of state electronic disease surveillance systems. This report summarizes the results of that assessment, which indicated a 17.5% increase from 40 states in 2007 to 47 states in 2010 with fully operational general communicable disease (GCD) electronic surveillance systems, a 211.5% increase from 13 to 39 states in the number of systems that were interoperable, a 22.4% increase from 23 to 34 states in the number with integrated systems, and a 20.0% increase to 42 states with the capacity to receive electronic laboratory reports (ELRs). New Centers for Medicare and Medicaid Services rules for meaningful use of health information technology encourage data exchange between electronic health record systems and public health agencies, including submission of ELRs. To meet national goals for health information exchange to improve population health, variation in disease surveillance systems should decrease, and functionality should increase.

  13. 7 CFR 1220.129 - State and United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.129 State and United...

  14. 7 CFR 1220.129 - State and United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.129 State and United...

  15. 7 CFR 1220.129 - State and United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.129 State and United...

  16. 7 CFR 1220.129 - State and United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.129 State and United...

  17. 7 CFR 1220.129 - State and United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.129 State and United...

  18. State-selective generation of molecular ions via Rydberg states

    NASA Astrophysics Data System (ADS)

    Grimes, David; Zhou, Yan; Barnum, Timothy; Coy, Stephen; Kay, Jeffrey; Field, Robert

    2014-05-01

    Autoionizing Rydberg states of molecules in the range n = 30-50 have the potential to enable the production of single quantum state selected ensembles of molecular ions, which have uses from spectroscopy to high precision measurements of fundamental constants. Multichannel Quantum Defect Theory (MQDT) fully describes the Rydberg states of molecules and the dynamics of autoionization. We have used our full MQDT description of CaF to determine optimal autoionizing resonances for producing a variety of selected rotation-vibration states of the ion. Progress towards experimental demonstrations in BaF will also be discussed. This work was supported by the NSF and an NDSEG Fellowship

  19. Chimera states in bursting neurons

    NASA Astrophysics Data System (ADS)

    Bera, Bidesh K.; Ghosh, Dibakar; Lakshmanan, M.

    2016-01-01

    We study the existence of chimera states in pulse-coupled networks of bursting Hindmarsh-Rose neurons with nonlocal, global, and local (nearest neighbor) couplings. Through a linear stability analysis, we discuss the behavior of the stability function in the incoherent (i.e., disorder), coherent, chimera, and multichimera states. Surprisingly, we find that chimera and multichimera states occur even using local nearest neighbor interaction in a network of identical bursting neurons alone. This is in contrast with the existence of chimera states in populations of nonlocally or globally coupled oscillators. A chemical synaptic coupling function is used which plays a key role in the emergence of chimera states in bursting neurons. The existence of chimera, multichimera, coherent, and disordered states is confirmed by means of the recently introduced statistical measures and mean phase velocity.

  20. Demystifiying state health insurance marketplaces.

    PubMed

    Hahn, Joyce A; Sheingold, Brenda Helen; Ott, Karen M

    2013-01-01

    The state health insurance exchanges, mandated under the Patient Protection and Affordable Care Act, will impact how health care is delivered and reimbursed, and will touch the lives of nurses in all professional roles. The dynamics of how each model will operate within each state is currently a work in progress. Nurses have a tradition of providing voice and leadership in the health care reform arena from the unique position as both consumers and health care professionals. The time is right to contact state legislators and advocate for nurses to sit on the governing boards of the state health care exchanges. Communication between nurses in all states should be an ongoing dialogue through specialty and state nursing organizations to ensure nursing is aware of both issues and best practices nationwide.

  1. Maintaining the unmethylated state

    PubMed Central

    2013-01-01

    Background A remarkable correspondence exists between the cytogenetic locations of the known fragile sites and frequently reported sites of hypermethylation. The best-known features of fragile sites are sequence motifs that are prone to the spontaneous formation of a non-B DNA structure. These facts, coupled with the known enzymological specificities of DNA methyltransferase 1 (DNMT1), the ATP-dependent and actin-dependent helicases, and the ten-eleven translocation (TET) dioxygenases, suggest that these enzymes are involved in an epigenetic cycle that maintains the unmethylated state at these sites by resolving non-B structure, preventing both the sequestration of DNA methyltransferases (DNMTs) and hypermethylation in normal cells. Presentation of the hypothesis The innate tendency of DNA sequences present at fragile sites to form non-B DNA structures results in de novo methylation of DNA at these sites that is held in check in normal cells by the action of ATP-dependent and actin-dependent helicases coupled with the action of TET dioxygenases. This constitutes a previously unrecognized epigenetic repair cycle in which spontaneously forming non-B DNA structures formed at fragile sites are methylated by DNMTs as they are removed by the action of ATP-dependent and actin-dependent helicases, with the resulting nascent methylation rendered non-transmissible by TET dioxygenases. Testing the hypothesis A strong prediction of the hypothesis is that knockdown of ATP-dependent and actin-dependent helicases will result in enhanced bisulfite sensitivity and hypermethylation at non-B structures in multiple fragile sites coupled with global hypomethylation. Implications of the hypothesis A key implication of the hypothesis is that helicases, like the lymphoid-specific helicase and alpha thalassemia/mental retardation syndrome X-linked helicase, passively promote accurate maintenance of DNA methylation by preventing the sequestration of DNMTs at sites of unrepaired non-B DNA

  2. New York State

    NASA Technical Reports Server (NTRS)

    2002-01-01

    On March 26, New York Mayor Michael Bloomberg declared a drought emergency for the city and four upstate counties in response to the worst drought to hit the eastern United States in nearly 70 years. Restrictions on water use will affect more than 8 million residents of New York. The city's reservoirs, located in the Catskill Mountains, are at 52 percent capacity. One of these, Ashokan Reservoir, is seen in this pair of ASTER images acquired on September 18, 2000 and February 3, 2002.

    These images were acquired by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER will image Earth for the next 6 years to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18,1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, California, is the U.S. Science team leader; Bjorn Eng of JPL is the project manager. ASTER is the only high resolution imaging sensor on Terra. The Terra mission is part of NASA's Earth Science Enterprise, along-term research and technology program designed to examine Earth's land, oceans, atmosphere, ice and life as a total integrated system.

    The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical

  3. State Estimation for Humanoid Robots

    DTIC Science & Technology

    2015-07-01

    natural for a controller to produce force commands to the robot using inverse dynamics. Model based control and state estimation relies on the accuracy of...produce force commands to the robot using inverse dynamics. Model based control and state estimation relies on the accuracy of the model. We address the...natural for a controller to produce force commands to the robot using inverse dynamics. Model based control and state estimation relies on the accuracy of

  4. B States at the Tevatron

    SciTech Connect

    Paulini, Manfred; /Carnegie Mellon U.

    2009-06-01

    The CDF and D0 experiments have produced a wealth of heavy flavor physics results since the beginning of RunII of the Fermilab Tevatron. They review recent measurements of B hadron states including excited B states (B**, B{sub s}**) and the B{sub c}{sup +} meson. They also summarize the discoveries of the {Sigma}{sub b} baryon states and the {Xi}{sub b}{sup -} baryon.

  5. State Identification in Nonlinear Systems

    SciTech Connect

    Holloway, James Paul

    2005-02-06

    A state estimation method based on finding a system state that causes a model to match a set of system measurements is regularized by requiring that sudden changes in system state be avoided. The required optimization is accomplished by a pattern search algorithm. The method does not require derivative information or linearization of the model. Is has been applied to a 10 dimensional model of a fast reactor system.

  6. Local cloning of entangled states

    SciTech Connect

    Gheorghiu, Vlad; Yu Li; Cohen, Scott M.

    2010-08-15

    We investigate the conditions under which a set S of pure bipartite quantum states on a DxD system can be locally cloned deterministically by separable operations, when at least one of the states is full Schmidt rank. We allow for the possibility of cloning using a resource state that is less than maximally entangled. Our results include that: (i) all states in S must be full Schmidt rank and equally entangled under the G-concurrence measure, and (ii) the set S can be extended to a larger clonable set generated by a finite group G of order |G|=N, the number of states in the larger set. It is then shown that any local cloning apparatus is capable of cloning a number of states that divides D exactly. We provide a complete solution for two central problems in local cloning, giving necessary and sufficient conditions for (i) when a set of maximally entangled states can be locally cloned, valid for all D; and (ii) local cloning of entangled qubit states with nonvanishing entanglement. In both of these cases, we show that a maximally entangled resource is necessary and sufficient, and the states must be related to each other by local unitary 'shift' operations. These shifts are determined by the group structure, so need not be simple cyclic permutations. Assuming this shifted form and partially entangled states, then in D=3 we show that a maximally entangled resource is again necessary and sufficient, while for higher-dimensional systems, we find that the resource state must be strictly more entangled than the states in S. All of our necessary conditions for separable operations are also necessary conditions for local operations and classical communication (LOCC), since the latter is a proper subset of the former. In fact, all our results hold for LOCC, as our sufficient conditions are demonstrated for LOCC, directly.

  7. State coal profiles, January 1994

    SciTech Connect

    Not Available

    1994-02-02

    The purpose of State Coal Profiles is to provide basic information about the deposits, production, and use of coal in each of the 27 States with coal production in 1992. Although considerable information on coal has been published on a national level, there is a lack of a uniform overview for the individual States. This report is intended to help fill that gap and also to serve as a framework for more detailed studies. While focusing on coal output, State Coal Profiles shows that the coal-producing States are major users of coal, together accounting for about three-fourths of total US coal consumption in 1992. Each coal-producing State is profiled with a description of its coal deposits and a discussion of the development of its coal industry. Estimates of coal reserves in 1992 are categorized by mining method and sulfur content. Trends, patterns, and other information concerning production, number of mines, miners, productivity, mine price of coal, disposition, and consumption of coal are detailed in statistical tables for selected years from 1980 through 1992. In addition, coal`s contribution to the State`s estimated total energy consumption is given for 1991, the latest year for which data are available. A US summary of all data is provided for comparing individual States with the Nation as a whole. Sources of information are given at the end of the tables.

  8. Guidance for state attainment plans

    SciTech Connect

    Strait, R.

    1994-06-01

    Title I of the Clean Air act Amendments of 1990 significantly changed requirements for regulatory agencies to prepare state implementation plans that demonstrate attainment of the ozone National Ambient Air Quality Standards. State agencies now are required to submit plans that show how they will meet the standards by their attainment date. EPA has published a series of guidance documents to assist states in preparing their plans. In addition, the agency is developing software to assist states in projecting emissions and tracking reductions. This article summarizes the guidance documents and software program.

  9. Single electron states in polyethylene

    SciTech Connect

    Wang, Y.; MacKernan, D.; Cubero, D. E-mail: n.quirke@imperial.ac.uk; Coker, D. F.; Quirke, N. E-mail: n.quirke@imperial.ac.uk

    2014-04-21

    We report computer simulations of an excess electron in various structural motifs of polyethylene at room temperature, including lamellar and interfacial regions between amorphous and lamellae, as well as nanometre-sized voids. Electronic properties such as density of states, mobility edges, and mobilities are computed on the different phases using a block Lanczos algorithm. Our results suggest that the electronic density of states for a heterogeneous material can be approximated by summing the single phase density of states weighted by their corresponding volume fractions. Additionally, a quantitative connection between the localized states of the excess electron and the local atomic structure is presented.

  10. State observer for synchronous motors

    DOEpatents

    Lang, Jeffrey H.

    1994-03-22

    A state observer driven by measurements of phase voltages and currents for estimating the angular orientation of a rotor of a synchronous motor such as a variable reluctance motor (VRM). Phase voltages and currents are detected and serve as inputs to a state observer. The state observer includes a mathematical model of the electromechanical operation of the synchronous motor. The characteristics of the state observer are selected so that the observer estimates converge to the actual rotor angular orientation and velocity, winding phase flux linkages or currents.

  11. Low-charge-state linac

    SciTech Connect

    Shepard, K.W.; Kim, J.W.

    1995-08-01

    A design is being developed for a low-charge-state linac suitable for injecting ATLAS with a low-charge-state, radioactive beam. Initial work indicates that the existing ATLAS interdigital superconducting accelerating structures, together with the superconducting quadrupole transverse focussing element discussed above, provides a basis for a high-performance low-charge-state linac. The initial 2 or 3 MV of such a linac could be based on a normally-conducting, low-frequency RFQ, possibly combined with 24-MHz superconducting interdigital structures. Beam dynamics studies of the whole low-charge-state post-accelerator section were carried out in early FY 1995.

  12. Change-state selector installed

    SciTech Connect

    Craig, S.L.; Nolen, J.A.; Phillips, D.

    1995-08-01

    The installation and early operation of the new charge-state selector after the PII linac was described above. Previous to the use of this device all charge states of beams stripped between the PII and Booster linacs entered the Booster. The beam power of the unused charge states often caused quenching of superconducting solenoids in the Booster. This problem is completely eliminated by the charge-state selector. It also eliminates the need to use {open_quotes}guide beams{close_quotes} from the tandem when tuning heavy beams which required stripping.

  13. Isomeric states in 253No

    NASA Astrophysics Data System (ADS)

    Lopez-Martens, A.; Hauschild, K.; Yeremin, A. V.; Dorvaux, O.; Belozerov, A. V.; Briançon, Ch.; Chelnokov, M. L.; Chepigin, V. I.; Curien, D.; Désesquelles, P.; Gall, B.; Gorshkov, V. A.; Guttormsen, M.; Hanappe, F.; Kabachenko, A. P.; Khalfallah, F.; Korichi, A.; Larsen, A. C.; Malyshev, O. N.; Minkova, A.; Oganessian, Yu. Ts.; Popeko, A. G.; Rousseau, M.; Rowley, N.; Sagaidak, R. N.; Sharo, S.; Shutov, A. V.; Siem, S.; Stuttgé, L.; Svirikhin, A. I.; Syed, N. U. H.; Theisen, Ch.

    2007-06-01

    Isomeric states in 253No have been investigated by conversion electron and γ -ray spectroscopy with the GABRIELA detection system. The 31μs isomer reported more than 30 years ago is found to decay to the ground state of 253No by the emission of a 167keV M2 transition. The spin and parity of this low-lying isomeric state are established to be 5/2+ . The presence of another longer-lived isomeric state is also discussed.

  14. Entanglement teleportation via werner states

    PubMed

    Lee; Kim

    2000-05-01

    Transfer of entanglement and information is studied for quantum teleportation of an unknown entangled state through noisy quantum channels. We find that the quantum entanglement of the unknown state can be lost during the teleportation even when the channel is quantum correlated. We introduce a fundamental parameter of correlation information which dissipates linearly during the teleportation through the noisy channel. Analyzing the transfer of correlation information, we show that the purity of the initial state is important in determining the entanglement of the replica state.

  15. State Energy Overview. [Contains glossary

    SciTech Connect

    Not Available

    1983-10-01

    An overview of selected energy-related data for the United States, for each state, and for the District of Columbia is presented. Included are the quantities of energy produced and consumed, estimates of fuel reserves, the value of nonrenewable fuels produced by type, energy expenditures, and consumer prices. Also provided for each state are selected demographic and energy-related information that have been ranked and expressed as a percent of the national total. This overview provides a ready reference and a quick access to selected state energy information and state rankings for various socioeconomic and energy items. The State Energy Overview is arranged in five sections. The first section presents United States totals and an overview of state rankings. The second depicts data for the 50 states and the District of Columbia. The glossary presents definitions germane to this publication and the fourth section describes methodology and includes remarks concerning the information and methods used to estimate 1982 consumption numbers. The fifth section presents sources of data and information for this publication. A summary of each section is included.

  16. Tetraquark state and multibody interaction

    SciTech Connect

    Deng Chengrong; Ping Jialun; Wang Fan; Goldman, T.

    2010-10-01

    The tetraquark states with diquark-anti-diquark configuration have been studied in the flux-tube model, in which the multibody confinement is used. In this model approach, the states Y(2175), f{sub 0}(600), f{sub 0}(980), and X(1576) can be assigned as tetraquark states. They are color confinement resonances with three-dimension structure. This study suggests that the multibody confinement should be employed in the quark model study of multiquark states instead of the additive two-body confinement.

  17. Tetraquark state and multibody interaction

    NASA Astrophysics Data System (ADS)

    Deng, Chengrong; Ping, Jialun; Wang, Fan; Goldman, T.

    2010-10-01

    The tetraquark states with diquark-anti-diquark configuration have been studied in the flux-tube model, in which the multibody confinement is used. In this model approach, the states Y(2175), f0(600), f0(980), and X(1576) can be assigned as tetraquark states. They are color confinement resonances with three-dimension structure. This study suggests that the multibody confinement should be employed in the quark model study of multiquark states instead of the additive two-body confinement.

  18. Accountability. State Implementation of Common Core State Standards

    ERIC Educational Resources Information Center

    Anderson, Kimberly; Mira, Mary Elizabeth

    2014-01-01

    All of the 15 states in this study have recently been involved in school accountability system reform. Since 2011, the states have taken advantage of a federal program to give them flexibility around certain accountability requirements of the "No Child Left Behind Act" of 2001 (NCLB), the most recent reauthorization of the Elementary and…

  19. Planning Linkages Between the States and Between States and Institutions.

    ERIC Educational Resources Information Center

    Folger, John K.

    The planning relationship between the federal government and the states, and between each state and its higher education institutions are considered. The federal government's role in higher education has had three major components: regulation, support of research in universities, and support of student aid programs. Federal regulation has…

  20. Summary Report. State Implementation of Common Core State Standards

    ERIC Educational Resources Information Center

    Anderson, Kimberly; Mira, Mary Elizabeth

    2014-01-01

    Implementation of college- and career-readiness standards is some of the most important work currently underway in states to improve public education and student achievement. This report provides a summary of findings from SREB's research into the efforts of 15 states--12 in the Southern Educational Research Board (SREB) region--to support…

  1. State Higher Education Budgeting Mechanisms in the United States

    ERIC Educational Resources Information Center

    Mizuta, Kensuke; Yoshida, Kana; Yanagiura, Takeshi

    2010-01-01

    (Purpose) The purpose of this study was to examine the correlation between certain characteristics of US states and their budgeting systems for higher education (HE), and to derive implications for Japanese HE budgeting policy from the results. (Methodology) The US's State Higher Education Executive Officers (SHEEO) conducted a 30-item…

  2. Teacher Involvement in Decisionmaking: A State-by-State Profile.

    ERIC Educational Resources Information Center

    Carnegie Foundation for the Advancement of Teaching, Princeton, NJ.

    The Carnegie Foundation recently completed a comprehensive survey of more than 20,000 teachers in all 50 states about their involvement in shaping classroom and school policy. The report consists of a brief introductory analysis of the survey by foundation president Ernest L. Boyer, followed by 10 tables presenting, for each state, the percentages…

  3. Directing Discipline: State Medical Board Responsiveness to State Legislatures.

    PubMed

    Lillvis, Denise F; McGrath, Robert J

    2017-02-01

    State medical boards are increasingly responsible for regulating medical and osteopathic licensure and professional conduct in the United States. Yet, there is great variation in the extent to which such boards take disciplinary action against physicians, indicating that some boards are more zealous regulators than others. We look to the political roots of such variation and seek to answer a simple, yet important, question: are nominally apolitical state medical boards responsive to political preferences? To address this question, we use panel data on disciplinary actions across sixty-four state medical boards from 1993 through 2006 and control for over-time changes in board characteristics (e.g., composition, independence, budgetary status), regulatory structure, and resources. We show that as state legislatures become more liberal [conservative], state boards increasingly [decreasingly] discipline physicians, especially during unified government and in the presence of highly professional legislatures. Our conclusions join others in emphasizing the importance of state medical boards and the contingent nature of political control of state regulation. In addition, we emphasize the roles that oversight capacity and strategy play in offsetting concerns regarding self-regulation of a powerful organized interest.

  4. State cigarette minimum price laws - United States, 2009.

    PubMed

    2010-04-09

    Cigarette price increases reduce the demand for cigarettes and thereby reduce smoking prevalence, cigarette consumption, and youth initiation of smoking. Excise tax increases are the most effective government intervention to increase the price of cigarettes, but cigarette manufacturers use trade discounts, coupons, and other promotions to counteract the effects of these tax increases and appeal to price-sensitive smokers. State cigarette minimum price laws, initiated by states in the 1940s and 1950s to protect tobacco retailers from predatory business practices, typically require a minimum percentage markup to be added to the wholesale and/or retail price. If a statute prohibits trade discounts from the minimum price calculation, these laws have the potential to counteract discounting by cigarette manufacturers. To assess the status of cigarette minimum price laws in the United States, CDC surveyed state statutes and identified those states with minimum price laws in effect as of December 31, 2009. This report summarizes the results of that survey, which determined that 25 states had minimum price laws for cigarettes (median wholesale markup: 4.00%; median retail markup: 8.00%), and seven of those states also expressly prohibited the use of trade discounts in the minimum retail price calculation. Minimum price laws can help prevent trade discounting from eroding the positive effects of state excise tax increases and higher cigarette prices on public health.

  5. State Tobacco Control Program Spending--United States, 2011.

    PubMed

    Huang, Jidong; Walton, Kimp; Gerzoff, Robert B; King, Brian A; Chaloupka, Frank J

    2015-06-26

    Evidence-based, statewide tobacco control programs that are comprehensive, sustained, and accountable reduce smoking rates and tobacco-related diseases and deaths. States that made larger investments in tobacco prevention and control have seen larger declines in cigarettes sales than the United States as a whole, and the prevalence of smoking has declined faster as spending for tobacco control programs has increased. CDC's Best Practices for Comprehensive Tobacco Control Programs (Best Practices) outlines the elements of an evidence-based state tobacco control program and provides recommended state funding levels to substantially reduce tobacco-related disease, disability, and death. To analyze states' spending in relation to program components outlined within Best Practices, CDC assessed state tobacco control programs' expenditures for fiscal year 2011. In 2011, states spent approximately $658 million on tobacco control and prevention, which accounts for less than 3% of the states' revenues from the sale of tobacco products and only 17.8% of the level recommended by CDC. Evidence suggests that funding tobacco prevention and control efforts at the levels recommended in Best Practices could achieve larger and more rapid reductions in tobacco use and associated morbidity and mortality.

  6. 7 CFR 1220.615 - State and United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false State and United States. 1220.615 Section 1220.615 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH,...

  7. 7 CFR 1220.615 - State and United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false State and United States. 1220.615 Section 1220.615 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH,...

  8. 7 CFR 1220.615 - State and United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false State and United States. 1220.615 Section 1220.615 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH,...

  9. 7 CFR 1220.615 - State and United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false State and United States. 1220.615 Section 1220.615 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SOYBEAN PROMOTION, RESEARCH,...

  10. California Report Card 2008: The State of the State's Children

    ERIC Educational Resources Information Center

    Children Now, 2008

    2008-01-01

    The California Report Card provides a clear, complete and concise picture of the state of the state's children along with recommendations for how we can better support our children through new and improved public policies. It assigns letter grades to such key indicators as health insurance, oral health, asthma, mental health, infant health,…

  11. Restructuring State Education Agencies: Learning from State Leaders. SERVE Report.

    ERIC Educational Resources Information Center

    Nelson, Linda J.

    Findings of a study that describes restructuring efforts undertaken by state education agencies (SEAs) are presented in this paper. Data were collected through telephone interviews with SEA officials in 24 states that were actively engaged in restructuring and analysis of SEA documents. Factors that contributed to restructuring included the place…

  12. Professional Development. State Implementation of Common Core State Standards

    ERIC Educational Resources Information Center

    Anderson, Kimberly; Mira, Mary Elizabeth

    2014-01-01

    The following profiles address how the state departments of education are helping educators prepare for and implement the Common Core and aligned assessments through professional learning. The major professional development efforts around the Common Core were examined in order to understand the overall efforts of each state. An exhaustive list of…

  13. The State of State Pre-Kindergarten Standards

    ERIC Educational Resources Information Center

    Neuman, S.B.; Roskos, K.

    2005-01-01

    Recent federal initiatives, including Good Start Grow Smart, and the Child Care and Development Grant (CCDF), call for states to develop early learning standards for children ages 3-5 in language, literacy and mathematics. To date, 43 states have such standards, with the remaining seven in progress. In this article, we argue that coherent, quality…

  14. 7 CFR 1160.104 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 9 2012-01-01 2012-01-01 false United States. 1160.104 Section 1160.104 Agriculture... Definitions § 1160.104 United States. United States means the 48 contiguous states in the continental United States and the District of Columbia, except that United States means the 50 states of the United......

  15. 7 CFR 1160.104 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 9 2014-01-01 2013-01-01 true United States. 1160.104 Section 1160.104 Agriculture... Definitions § 1160.104 United States. United States means the 48 contiguous states in the continental United States and the District of Columbia, except that United States means the 50 states of the United......

  16. 7 CFR 1160.104 - United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 9 2013-01-01 2013-01-01 false United States. 1160.104 Section 1160.104 Agriculture... Definitions § 1160.104 United States. United States means the 48 contiguous states in the continental United States and the District of Columbia, except that United States means the 50 states of the United......

  17. 7 CFR 1160.104 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true United States. 1160.104 Section 1160.104 Agriculture... Definitions § 1160.104 United States. United States means the 48 contiguous states in the continental United States and the District of Columbia, except that United States means the 50 states of the United......

  18. 7 CFR 1160.104 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false United States. 1160.104 Section 1160.104 Agriculture... Definitions § 1160.104 United States. United States means the 48 contiguous states in the continental United States and the District of Columbia, except that United States means the 50 states of the United......

  19. States Seek Flexibility on Testing

    ERIC Educational Resources Information Center

    McNeil, Michele; Gewertz, Catherine

    2013-01-01

    With the debut of common assessments less than two years away, states and districts are worried about the accountability systems that hinge on those tests. A growing chorus of policy groups is urging more flexibility in how states evaluate teachers, label schools, and enforce other high-stakes consequences during what's likely to be a messy…

  20. Liquidlike state of dense hydrogen

    NASA Technical Reports Server (NTRS)

    Carlsson, A. E.; Ashcroft, N. W.

    1984-01-01

    Some difficulties associated with estimates of the ground-state energy difference between liquid and solid metallic hydrogen based on many-body perturbation theory are pointed out. Arguments based on liquid-state perturbation theory which indicate that the energy difference may be much smaller than was found in a previous calculation are presented.

  1. Equilibrium states for hyperbolic potentials

    NASA Astrophysics Data System (ADS)

    Ramos, Vanessa; Viana, Marcelo

    2017-02-01

    We prove the existence of finitely many ergodic equilibrium states for local homeomorphisms and hyperbolic potentials. We also deal with partially hyperbolic skew-products over non-uniformly expanding maps with uniform contraction on the fibre. For these systems we prove the existence and finiteness of the equilibrium states associated with a class of Hölder continuous potentials.

  2. Washington State 1995 Data Book.

    ERIC Educational Resources Information Center

    Washington State Office of Financial Management, Olympia.

    This document is intended to present, in tables and graphs, a diversity of information on Washington State, its people, economy, and government. The information was obtained from state and federal agencies and from private businesses. The data are organized into 11 major chapters which cover the following topics (sample subtopics in parentheses):…

  3. Seeking a State Workforce Strategy

    ERIC Educational Resources Information Center

    Fischer, David Jason; Mack, Melinda

    2015-01-01

    New York's workforce system is a complicated entity that engages nearly a dozen state agencies and myriad funding streams originating at the federal and state levels, and operates on the ground in ten economic development regions, 33 designated workforce investment areas, community-based organizations, labor unions and 62 counties. This report…

  4. Standards Draw Heat in States

    ERIC Educational Resources Information Center

    Ujifusa, Andrew

    2013-01-01

    Opponents of the Common Core State Standards are ramping up legislative pressure and public relations efforts aimed at getting states to scale back--or even abandon--the high-profile initiative, even as implementation proceeds and tests aligned with the standards loom. Critics of the common core have focused recent lobbying and media efforts on…

  5. State Governance Action Report, 2008

    ERIC Educational Resources Information Center

    Ogle, Greg

    2008-01-01

    This is the fifth edition of the State Governance Action Report that has been produced since 2000 by the Association of Governing Boards of Universities and Colleges' (AGB's) Ingram Center for Public Trusteeship and Governance. Focusing primarily on state and higher education policies directly affecting governance, trusteeship, and institutionally…

  6. Federal, State, and Local regulations

    SciTech Connect

    Kelly, J.M.; Brandenburg, B.L. )

    1991-08-01

    This article is a review of federal, state, and local regulations pertinent treatment of leachate from hazardous materials landfills in California. The topics covered include under federal regulations: pretreatment, whole-effluent toxicity, hazardous waste regulation; under state regulations: hazardous waste regulations, air toxics, environmental quality act; under local regulations: local limits, toxicity-regional water quality board, air emissions and district code.

  7. The Journey for Jackson State

    ERIC Educational Resources Information Center

    Roach, Ronald

    2007-01-01

    This article profiles Jackson State University, a historically Black school of more than 8,000 students located at the southern end of Jackson, Mississippi's majority-Black capital city. Founded in 1877, Jackson State has emerged as one of Mississippi's leading research institutions as well as one of the top HBCUs in the country for research. Its…

  8. Lee v. State of Oregon.

    PubMed

    Devlin, M M

    1996-01-01

    HELD: Oregon's Death with Dignity Act, Measure 16, which legalizes physician-assisted suicide for certain terminally ill persons, violates the equal protection clause of the fourteenth amendment to the United States Constitution. Measure 16 fails to withstand even the lowest level of judicial scrutiny because the disparate treatment afforded the class of terminally ill persons does not further any legitimate state interest.

  9. X, Y and Z States

    NASA Astrophysics Data System (ADS)

    Nielsen, M.; Albuquerque, R. M.; Dias, J. M.; Khemchandani, K. P.; Martínez Torres, A.; Navarra, F. S.; Zanetti, C. M.

    2017-03-01

    Many new states in the charmonium mass region were recently discovered by BaBar, Belle, CLEO-c, CDF, DØ, BESIII, LHCb and CMS Collaborations. We use the QCD Sum Rule approach to study the possible structure of some of these states.

  10. User Guide for State Summaries

    EPA Pesticide Factsheets

    The EPA developed state-level summaries of chemical and water use using the project database developed from FracFocus 1.0 disclosures with some limited background information on oil and gas production, geology, and regulations for the state.

  11. Climates of the United States.

    ERIC Educational Resources Information Center

    Baldwin, John L.

    This document is designed to provide basic information about the climates of the United States and the causes of these climates. Events of interest in the climatological history of the United States are described and illustrated by many maps, charts and diagrams. The booklet has three major parts. Part I discusses climate and climate control in…

  12. Equation of State of Solids.

    DTIC Science & Technology

    The report describes a program for computing equation of state parameters for a material which undergoes a phase transition, either rate-dependent or...obtaining explicit temperature dependence if measurements are made at three temperatures. It is applied to data from calcite. Finally a theoretical equation of state is described for solid iron. (Author)

  13. Minnesota State High School League.

    ERIC Educational Resources Information Center

    Minnesota State Office of the Legislative Auditor, St. Paul. Program Evaluation Div.

    The Minnesota State High School League administers a program of competitive athletic, musical, speech, and dramatics activities at district, region, and state levels. The league is a voluntary association of 433 public and 49 private schools. This monograph reports on a study of the league in regard to two questions: (1) Are policy-making and…

  14. State Licensing of Health Occupations.

    ERIC Educational Resources Information Center

    National Center for Health Statistics (DHEW/PHS), Hyattsville, MD.

    About 25 health professions and occupations are licensed by one or more states according to the survey of state licensing provisions by the National Center for Health Statistics. Data is presented in 22 chapters on the licensure of administrators, chiropractors, clinical laboratory personnel, dental hygienists, dentists, professional engineers,…

  15. Department Raps States on Testing

    ERIC Educational Resources Information Center

    Olson, Lynn

    2006-01-01

    The U.S. Department of Education has notified 10 states that it intends to withhold a portion of their state administrative funds under the Title I program for failing to comply fully with the testing provisions of the No Child Left Behind Act by the end of the 2005-06 school year. Those funds would instead be diverted directly to school…

  16. State Governance of Education: 1983.

    ERIC Educational Resources Information Center

    Burnes, Donald W.; And Others

    The authors report on major trends and emerging issues in state education policy-making. Two parts cover, first, the history, status, and future of educational governance and, second, the alternatives open to state leaders in structuring and using education commissions. In accounting for trends in educational governance, the authors consider such…

  17. Landforms of the United States.

    ERIC Educational Resources Information Center

    Geological Survey (Dept. of Interior), Reston, VA.

    One of a series of general interest publications on science topics, the booklet provides those interested in landforms of the United States with a nontechnical introduction to the subject. Separate sections examine deposital versus erosional landforms in the central stable region of the United States, the Appalachian Highlands, the Ozark Region,…

  18. State Governance Action Report, 2007

    ERIC Educational Resources Information Center

    Association of Governing Boards of Universities and Colleges, 2007

    2007-01-01

    This paper presents the State Governance Action Report for 2007. Compiled in this report are state policy developments, including legislation, commissions, and studies, affecting the structure, responsibilities, and operations of public higher education governing boards and institutionally related foundations. Governance and governance-related…

  19. Confusional state and cerebral infarcts.

    PubMed Central

    García-Albea, E.

    1989-01-01

    Thirteen patients with confusional state and cerebral infarction were studied. Seven patients had optic pathway alterations. On computed tomographic scan, 2 patients had multiple infarctions and 10 had single infarctions, predominantly located in the temporo-occipital associative cortex. One patient had a normal scan. Reduction of 'selective attention', 'release' hallucinations, amnesic syndrome and secondary individual adjustment could explain the confusional state. PMID:2608563

  20. State Incentive Funding: Leveraging Quality.

    ERIC Educational Resources Information Center

    Holland, Barbara

    1990-01-01

    This newsletter summarizes the debate on the use of state-level initiatives as levers to effect fundamental changes in higher education. It provides several perspectives on the use of incentive/enhancement programs to achieve state higher education goals. The concept of budgetary leverage is outlined, and the growth in enhancement programs…

  1. Fiscal Worries Shadow State Elections

    ERIC Educational Resources Information Center

    McNeil, Michele

    2008-01-01

    This article reports that the new class of governors and state legislators to be elected November 4 will inherit financial problems that pose both immediate and long-term threats to existing education programs, while constraining their ability to mount new initiatives. The prospect of a deepening economic slowdown--with state-level budget deficits…

  2. Centennial State Libraries Newsletter, 1999.

    ERIC Educational Resources Information Center

    Sagee, Kathleen D., Ed.

    1999-01-01

    This document consists of 12 consecutive issues of the monthly "Centennial State Libraries" newsletter, of the Colorado Department of Education State Library and Adult Education Office. The issues cover the year 1999. Each issue--except the August issue which is an Annual Report--includes some or all of the following sections: current…

  3. Stable States of Biological Organisms

    NASA Astrophysics Data System (ADS)

    Yukalov, V. I.; Sornette, D.; Yukalova, E. P.; Henry, J.-Y.; Cobb, J. P.

    2009-04-01

    A novel model of biological organisms is advanced, treating an organism as a self-consistent system subject to a pathogen flux. The principal novelty of the model is that it describes not some parts, but a biological organism as a whole. The organism is modeled by a five-dimensional dynamical system. The organism homeostasis is described by the evolution equations for five interacting components: healthy cells, ill cells, innate immune cells, specific immune cells, and pathogens. The stability analysis demonstrates that, in a wide domain of the parameter space, the system exhibits robust structural stability. There always exist four stable stationary solutions characterizing four qualitatively differing states of the organism: alive state, boundary state, critical state, and dead state.

  4. Emergence of multicluster chimera states

    NASA Astrophysics Data System (ADS)

    Yao, Nan; Huang, Zi-Gang; Grebogi, Celso; Lai, Ying-Cheng

    2015-09-01

    A remarkable phenomenon in spatiotemporal dynamical systems is chimera state, where the structurally and dynamically identical oscillators in a coupled networked system spontaneously break into two groups, one exhibiting coherent motion and another incoherent. This phenomenon was typically studied in the setting of non-local coupling configurations. We ask what can happen to chimera states under systematic changes to the network structure when links are removed from the network in an orderly fashion but the local coupling topology remains invariant with respect to an index shift. We find the emergence of multicluster chimera states. Remarkably, as a parameter characterizing the amount of link removal is increased, chimera states of distinct numbers of clusters emerge and persist in different parameter regions. We develop a phenomenological theory, based on enhanced or reduced interactions among oscillators in different spatial groups, to explain why chimera states of certain numbers of clusters occur in certain parameter regions. The theoretical prediction agrees well with numerics.

  5. State-to-state dynamics of molecular energy transfer

    SciTech Connect

    Gentry, W.R.; Giese, C.F.

    1993-12-01

    The goal of this research program is to elucidate the elementary dynamical mechanisms of vibrational and rotational energy transfer between molecules, at a quantum-state resolved level of detail. Molecular beam techniques are used to isolate individual molecular collisions, and to control the kinetic energy of collision. Lasers are used both to prepare specific quantum states prior to collision by stimulated-emission pumping (SEP), and to measure the distribution of quantum states in the collision products by laser-induced fluorescence (LIF). The results are interpreted in terms of dynamical models, which may be cast in a classical, semiclassical or quantum mechanical framework, as appropriate.

  6. 7 CFR 1209.21 - State and United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order... the United States of America, the District of Columbia, and the Commonwealth of Puerto Rico....

  7. 7 CFR 1209.21 - State and United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order... the United States of America, the District of Columbia, and the Commonwealth of Puerto Rico....

  8. 7 CFR 1209.21 - State and United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order... the United States of America, the District of Columbia, and the Commonwealth of Puerto Rico....

  9. 7 CFR 1209.21 - State and United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order... the United States of America, the District of Columbia, and the Commonwealth of Puerto Rico....

  10. 7 CFR 1209.21 - State and United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order... the United States of America, the District of Columbia, and the Commonwealth of Puerto Rico....

  11. Capillary states of granular materials in the funicular state

    NASA Astrophysics Data System (ADS)

    Delenne, Jean-Yves; Richefeu, Vincent; Radjai, Farhang

    2013-06-01

    Using a multi-phase lattice Boltzmann model, we investigate the capillary states of a 2D granular packing gradually saturated by condensation from a homogeneously injected vapor phase. The internal stresses induced by surface tension and Laplace pressure are directly calculated from the forces acting on the grains with increasing amount of liquid. The evolution of cohesive strength with the amount of liquid reveals four different states reflecting the connectivity of the liquid phase and local grain environments. It increases in the pendular state, characterized by binary liquid bridges holding the grains together, and within the funicular state with an increasing number of liquid clusters connected to several grains. Beyond 40% of saturation, the cohesive strength falls off due to a decreasing Laplace pressure of liquid clusters.

  12. 77 FR 72742 - Approval and Promulgation of State Implementation Plans: State of Washington; Regional Haze State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... (TransAlta). The Washington State Department of Ecology (Ecology) submitted its Regional Haze State... at 40 CFR 50.308. On December 29, 2011 Ecology submitted an update to the SIP submittal containing a...? Ecology submitted its Regional Haze SIP on December 22, 2010 to meet the requirements of 40 CFR 50.308....

  13. Reusable State Machine Code Generator

    NASA Astrophysics Data System (ADS)

    Hoffstadt, A. A.; Reyes, C.; Sommer, H.; Andolfato, L.

    2010-12-01

    The State Machine model is frequently used to represent the behaviour of a system, allowing one to express and execute this behaviour in a deterministic way. A graphical representation such as a UML State Chart diagram tames the complexity of the system, thus facilitating changes to the model and communication between developers and domain experts. We present a reusable state machine code generator, developed by the Universidad Técnica Federico Santa María and the European Southern Observatory. The generator itself is based on the open source project architecture, and uses UML State Chart models as input. This allows for a modular design and a clean separation between generator and generated code. The generated state machine code has well-defined interfaces that are independent of the implementation artefacts such as the middle-ware. This allows using the generator in the substantially different observatory software of the Atacama Large Millimeter Array and the ESO Very Large Telescope. A project-specific mapping layer for event and transition notification connects the state machine code to its environment, which can be the Common Software of these projects, or any other project. This approach even allows to automatically create tests for a generated state machine, using techniques from software testing, such as path-coverage.

  14. Tetraquark states from lattice QCD

    SciTech Connect

    Mathur, Nilmani

    2011-10-24

    Recently there have been considerable interests in studying hadronic states beyond the usual two and three quark configurations. With the renewed experimental interests in {sigma}(600) and the inability of quark model to incorporate too many light scalar mesons, it is quite appropriate to study hadronic states with four quark configurations. Moreover, some of the newly observed charmed hadrons may well be described by four quark configurations. Lattice QCD is perhaps the most desirable tool to adjudicate the theoretical controversy of the scalar mesons and to interpret the structures of the newly observed charmed states. Here we briefly reviewed the lattice studies of four-quark hadrons.

  15. Determinate-state convolutional codes

    NASA Technical Reports Server (NTRS)

    Collins, O.; Hizlan, M.

    1991-01-01

    A determinate state convolutional code is formed from a conventional convolutional code by pruning away some of the possible state transitions in the decoding trellis. The type of staged power transfer used in determinate state convolutional codes proves to be an extremely efficient way of enhancing the performance of a concatenated coding system. The decoder complexity is analyzed along with free distances of these new codes and extensive simulation results is provided of their performance at the low signal to noise ratios where a real communication system would operate. Concise, practical examples are provided.

  16. State building energy codes status

    SciTech Connect

    1996-09-01

    This document contains the State Building Energy Codes Status prepared by Pacific Northwest National Laboratory for the U.S. Department of Energy under Contract DE-AC06-76RL01830 and dated September 1996. The U.S. Department of Energy`s Office of Codes and Standards has developed this document to provide an information resource for individuals interested in energy efficiency of buildings and the relevant building energy codes in each state and U.S. territory. This is considered to be an evolving document and will be updated twice a year. In addition, special state updates will be issued as warranted.

  17. 31 CFR 800.225 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false United States. 800.225 Section 800.225... FOREIGN PERSONS Definitions § 800.225 United States. The term United States or U.S. means the United States of America, the States of the United States, the District of Columbia, and any...

  18. 31 CFR 800.225 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false United States. 800.225 Section 800.225... FOREIGN PERSONS Definitions § 800.225 United States. The term United States or U.S. means the United States of America, the States of the United States, the District of Columbia, and any...

  19. 31 CFR 800.225 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false United States. 800.225 Section 800.225... FOREIGN PERSONS Definitions § 800.225 United States. The term United States or U.S. means the United States of America, the States of the United States, the District of Columbia, and any...

  20. 31 CFR 800.225 - United States.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false United States. 800.225 Section 800.225... FOREIGN PERSONS Definitions § 800.225 United States. The term United States or U.S. means the United States of America, the States of the United States, the District of Columbia, and any...

  1. 31 CFR 800.225 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States. 800.225 Section 800... TAKEOVERS BY FOREIGN PERSONS Definitions § 800.225 United States. The term United States or U.S. means the United States of America, the States of the United States, the District of Columbia, and any...

  2. 40 CFR 172.23 - State plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false State plans. 172.23 Section 172.23... PERMITS State Issuance of Experimental Use Permits § 172.23 State plans. (a) Submission. (1) A State may, by submitting a State plan, request the Administrator to authorize the designated State agency...

  3. 40 CFR 172.23 - State plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false State plans. 172.23 Section 172.23... PERMITS State Issuance of Experimental Use Permits § 172.23 State plans. (a) Submission. (1) A State may, by submitting a State plan, request the Administrator to authorize the designated State agency...

  4. 40 CFR 172.23 - State plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false State plans. 172.23 Section 172.23... PERMITS State Issuance of Experimental Use Permits § 172.23 State plans. (a) Submission. (1) A State may, by submitting a State plan, request the Administrator to authorize the designated State agency...

  5. An Empirical State Error Covariance Matrix for Batch State Estimation

    NASA Technical Reports Server (NTRS)

    Frisbee, Joseph H., Jr.

    2011-01-01

    State estimation techniques serve effectively to provide mean state estimates. However, the state error covariance matrices provided as part of these techniques suffer from some degree of lack of confidence in their ability to adequately describe the uncertainty in the estimated states. A specific problem with the traditional form of state error covariance matrices is that they represent only a mapping of the assumed observation error characteristics into the state space. Any errors that arise from other sources (environment modeling, precision, etc.) are not directly represented in a traditional, theoretical state error covariance matrix. Consider that an actual observation contains only measurement error and that an estimated observation contains all other errors, known and unknown. It then follows that a measurement residual (the difference between expected and observed measurements) contains all errors for that measurement. Therefore, a direct and appropriate inclusion of the actual measurement residuals in the state error covariance matrix will result in an empirical state error covariance matrix. This empirical state error covariance matrix will fully account for the error in the state estimate. By way of a literal reinterpretation of the equations involved in the weighted least squares estimation algorithm, it is possible to arrive at an appropriate, and formally correct, empirical state error covariance matrix. The first specific step of the method is to use the average form of the weighted measurement residual variance performance index rather than its usual total weighted residual form. Next it is helpful to interpret the solution to the normal equations as the average of a collection of sample vectors drawn from a hypothetical parent population. From here, using a standard statistical analysis approach, it directly follows as to how to determine the standard empirical state error covariance matrix. This matrix will contain the total uncertainty in the

  6. State/Federal Regulatory Considerations

    EPA Pesticide Factsheets

    This page contains presentations from the Brown to Green: Make the Connection to Renewable Energy workshop held in Santa Fe, New Mexico, during December 10-11, 2008, regarding State/Federal Regulatory Considerations.

  7. State of the Lab 2012

    ScienceCinema

    King, Alex

    2016-07-12

    Ames Laboratory Director Alex King delivers the annual State of the Lab address on Thursday, May 17, 2012, the 65th Anniversary of the founding of The Ames Laboratory. This video contains highlights from the address.

  8. Wright State Expands Continuing Education

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1974

    1974-01-01

    By leasing the Eugene W. Kettering Engineering and Science Center in downtown Dayton, Ohio, Wright State University plans to enlarge significantly its activities in continuing education for engineers, scientists, and others. (JR)

  9. Disturbance maintains alternative biome states.

    PubMed

    Dantas, Vinícius de L; Hirota, Marina; Oliveira, Rafael S; Pausas, Juli G

    2016-01-01

    Understanding the mechanisms controlling the distribution of biomes remains a challenge. Although tropical biome distribution has traditionally been explained by climate and soil, contrasting vegetation types often occur as mosaics with sharp boundaries under very similar environmental conditions. While evidence suggests that these biomes are alternative states, empirical broad-scale support to this hypothesis is still lacking. Using community-level field data and a novel resource-niche overlap approach, we show that, for a wide range of environmental conditions, fire feedbacks maintain savannas and forests as alternative biome states in both the Neotropics and the Afrotropics. In addition, wooded grasslands and savannas occurred as alternative grassy states in the Afrotropics, depending on the relative importance of fire and herbivory feedbacks. These results are consistent with landscape scale evidence and suggest that disturbance is a general factor driving and maintaining alternative biome states and vegetation mosaics in the tropics.

  10. State Regulation of Private Education.

    ERIC Educational Resources Information Center

    Lines, Patricia M.

    1982-01-01

    Examines state laws and the actions of various courts on home instruction and unauthorized educational programs. Suggests reforming the regulation of private education through legislative action that requires periodic testing as an alternative to compulsory school attendance. (Author/MLF)

  11. State of the Lab 2012

    SciTech Connect

    King, Alex

    2012-01-01

    Ames Laboratory Director Alex King delivers the annual State of the Lab address on Thursday, May 17, 2012, the 65th Anniversary of the founding of The Ames Laboratory. This video contains highlights from the address.

  12. Bound states in string nets

    NASA Astrophysics Data System (ADS)

    Schulz, Marc Daniel; Dusuel, Sébastien; Vidal, Julien

    2016-11-01

    We discuss the emergence of bound states in the low-energy spectrum of the string-net Hamiltonian in the presence of a string tension. In the ladder geometry, we show that a single bound state arises either for a finite tension or in the zero-tension limit depending on the theory considered. In the latter case, we perturbatively compute the binding energy as a function of the total quantum dimension. We also address this issue in the honeycomb lattice where the number of bound states in the topological phase depends on the total quantum dimension. Finally, the internal structure of these bound states is analyzed in the zero-tension limit.

  13. Changing state structures: outside in.

    PubMed

    Krasner, Stephen D

    2011-12-27

    In explaining the development of institutional structures within states, social science analysis has focused on autochthonous factors and paid less attention to the way in which external factors, especially purposive agent-directed as opposed to more general environmental factors, can influence domestic authority structures. For international relations scholarship, this lacunae is particularly troubling or perhaps, just weird. If the international system is anarchical, then political leaders can pursue any policy option. In some cases, the most attractive option would be conventional state to state interactions, diplomacy, or war. In other instances, however, changing the domestic authority structures of other states might be more appealing. In some cases, domestic authority structures have been influenced through bargaining, and in others through power. Power may reflect either explicit agent-oriented decisions or social processes that reflect the practices, values, and norms of more powerful entities.

  14. Experiments with Unusual Oxidation States

    ERIC Educational Resources Information Center

    Kauffman, G. B.

    1975-01-01

    Describes four synthesis experiments, adapted for the general chemistry laboratory, in which compounds in unusual oxidation are prepared. The abnormal oxidation states involved in the synthesis products are: silver (II), chromium (II), lead (IV), and bromine (I). (MLH)

  15. LANDSAT information for state planning

    NASA Technical Reports Server (NTRS)

    Faust, N. L.; Spann, G. W.

    1977-01-01

    The transfer of remote sensing technology for the digital processing of LANDSAT data to state and local agencies in Georgia and other southeastern states is discussed. The project consists of a series of workshops, seminars, and demonstration efforts, and transfer of NASA-developed hardware concepts and computer software to state agencies. Throughout the multi-year effort, digital processing techniques have been emphasized classification algorithms. Software for LANDSAT data rectification and processing have been developed and/or transferred. A hardware system is available at EES (engineering experiment station) to allow user interactive processing of LANDSAT data. Seminars and workshops emphasize the digital approach to LANDSAT data utilization and the system improvements scheduled for LANDSATs C and D. Results of the project indicate a substantially increased awareness of the utility of digital LANDSAT processing techniques among the agencies contracted throughout the southeast. In Georgia, several agencies have jointly funded a program to map the entire state using digitally processed LANDSAT data.

  16. Changing state structures: Outside in

    PubMed Central

    Krasner, Stephen D.

    2011-01-01

    In explaining the development of institutional structures within states, social science analysis has focused on autochthonous factors and paid less attention to the way in which external factors, especially purposive agent-directed as opposed to more general environmental factors, can influence domestic authority structures. For international relations scholarship, this lacunae is particularly troubling or perhaps, just weird. If the international system is anarchical, then political leaders can pursue any policy option. In some cases, the most attractive option would be conventional state to state interactions, diplomacy, or war. In other instances, however, changing the domestic authority structures of other states might be more appealing. In some cases, domestic authority structures have been influenced through bargaining, and in others through power. Power may reflect either explicit agent-oriented decisions or social processes that reflect the practices, values, and norms of more powerful entities. PMID:22198756

  17. A novel extended state observer.

    PubMed

    Xiong, Shaofeng; Wang, Weihong; Liu, Xiaodong; Chen, Zengqiang; Wang, Sen

    2015-09-01

    A novel extended state observer, which feeds back the output estimation error via both nonlinear and switching terms, is put forward for the first time in this paper. No longer neglecting the lumped uncertainty׳s first time derivative, the problem of disturbance observer design is transformed into the problem of state observer design in the presence of external disturbance. The switching term of the output estimation error is employed to counteract the adverse effect of external disturbance. The newly developed extended state observer provides an attractive solution to the issue of high precision motion control system. Both numerical simulation and experimentation on a speed turntable with temperature box are implemented to verify the performance of the proposed newly developed extended state observer.

  18. Einstein's steady-state cosmology

    NASA Astrophysics Data System (ADS)

    O'Raifeartaigh, Cormac

    2014-09-01

    Last year, a team of Irish scientists discovered an unpublished manuscript by Einstein in which he attempted to construct a "steady-state" model of the universe. Cormac O'Raifeartaigh describes the excitement of finding this previously unknown work.

  19. Air Pollution over the States

    ERIC Educational Resources Information Center

    Environmental Science and Technology, 1972

    1972-01-01

    State plans for implementing air quality standards are evaluated together with problems in modeling procedures and enforcement. Monitoring networks, standards, air quality regions, and industrial problems are also discussed. (BL)

  20. Optimal preparation of graph states

    SciTech Connect

    Cabello, Adan; Lopez-Tarrida, Antonio J.; Danielsen, Lars Eirik; Portillo, Jose R.

    2011-04-15

    We show how to prepare any graph state of up to 12 qubits with (a) the minimum number of controlled-Z gates and (b) the minimum preparation depth. We assume only one-qubit and controlled-Z gates. The method exploits the fact that any graph state belongs to an equivalence class under local Clifford operations. We extend up to 12 qubits the classification of graph states according to their entanglement properties, and identify each class using only a reduced set of invariants. For any state, we provide a circuit with both properties (a) and (b), if it does exist, or, if it does not, one circuit with property (a) and one with property (b), including the explicit one-qubit gates needed.

  1. State Support of Domestic Production

    SciTech Connect

    Amy Wright

    2007-12-30

    This project was developed in response to a cooperative agreement offering by the U.S. Department of Energy (DOE) and the National Energy Technology Laboratory (NETL) under the State Support of Domestic Production DE-FC26-04NT15456. The Interstate Oil and Gas Compact Commission (IOGCC) performed efforts in support of State programs related to the security, reliability and growth if our nation's domestic production of oil and natural gas. The project objectives were to improve the States ability to monitor the security of oil and gas operations; to maximize the production of domestic oil and natural gas thereby minimizing the threat to national security posed by interruptions in energy imports; to assist States in developing and maintaining high standards of environmental protection; to assist in addressing issues that limit the capacity of the industry; to promote the deployment of the appropriate application of technology for regulatory efficiency; and to inform the public about emerging energy issues.

  2. A State Nurses' Association Perspective.

    ERIC Educational Resources Information Center

    Boyer, Cheryl M.

    1983-01-01

    Discusses the accreditation and evolution of continuing education programs developed by state nurses' associations and other nursing organizations and the value of the accreditation. Also relates current accreditation system to the future of professional continuing education. (JOW)

  3. Clean Water State Revolving Fund

    EPA Pesticide Factsheets

    How the Clean Water State Revolving Fund works, how to obtain funding, program eligibility, innovative ways to use the funds to get the greatest water quality benefits and leverage financial resources of the program, and share success stories.

  4. Reinventing the state spaceport concept

    NASA Astrophysics Data System (ADS)

    Gormel, Edmond

    2002-01-01

    Spaceport Florida Authority, or ``the Authority,'' is meeting the challenge of reinventing the state spaceport concept. The Authority, an economic and academic development agency and a transportation authority that maximizes the strong NASA and military space presence in the state of Florida, serves as a facilitator among industry, education and government sectors that reside on or use Florida's spaceport. This paper discusses the state of Florida's progression in the business of space. From Florida's vision to be a leader in the commercialization of space to it's current role of partnering to grow over six hundred and fifty ($650) million dollars in new space programs. Executive Director Ed Gormel's strategy for reinventing a state spaceport is outlined in the paper. These guidelines, which he believes reflect the needs of the twenty-first century customer, include customer support, financing, property access and a means to provide dependable infrastructure. .

  5. State-to-State Mode Specificity: Energy Sequestration and Flow Gated by Transition State.

    PubMed

    Zhao, Bin; Sun, Zhigang; Guo, Hua

    2015-12-23

    Energy flow and sequestration at the state-to-state level are investigated for a prototypical four-atom reaction, H2 + OH → H + H2O, using a transition-state wave packet (TSWP) method. The product state distribution is found to depend strongly on the reactant vibrational excitation, indicating mode specificity at the state-to-state level. From a local-mode perspective, it is shown that the vibrational excitation of the H2O product derives from two different sources, one attributable to the energy flow along the reaction coordinate into the newly formed OH bond and the other due to the sequestration of the vibrational energy in the OH spectator moiety during the reaction. The analysis provided a unified interpretation of some seemingly contradicting experimental observations. It is further shown that the transfer of vibrational energy from the OH reactant to H2O product is gated by the transition state, accomplished coherently by multiple TSWPs with the corresponding OH vibrational excitation.

  6. Topological edge states in pnictides

    NASA Astrophysics Data System (ADS)

    Youmans, Cody; Ghaemi, Pouyan; Kargarian, Mehdi

    In some members of the ferro-pnictides, non-trivial topology in the bulk band-structure is related to potentially observable gapless edge states. We study these states numerically and analytically for a range of parameters, with and without superconductivity and antiferromagnetic SDW ordering, and their relation to the symmetries and topologically non-trivial aspects of our model Hamiltonian. Support was provided by the Doctoral Student Research Grant program at the Graduate Center, CUNY.

  7. Coherent States for Hopf Algebras

    NASA Astrophysics Data System (ADS)

    Škoda, Zoran

    2007-07-01

    Families of Perelomov coherent states are defined axiomatically in the context of unitary representations of Hopf algebras. A global geometric picture involving locally trivial noncommutative fibre bundles is involved in the construction. If, in addition, the Hopf algebra has a left Haar integral, then a formula for noncommutative resolution of identity in terms of the family of coherent states holds. Examples come from quantum groups.

  8. BPS states in string theory

    NASA Astrophysics Data System (ADS)

    Andriyash, Evgeny

    In this thesis we discuss a number of interesting and important properties of BPS states in string theory. We study wall-crossing behavior of BPS states at large volume limit and implications of it for the OSV conjecture. We find that the weak topological coupling OSV conjecture can be true at most in a special chamber of the Kahler cone. We also clarify an interesting puzzle arising in the description of BPS states on the Higgs branch of supersymmetic quantum mechanics. Using methods of toric geometry we compute Hilbert spaces of BPS states on the compactified Higgs branch and arrive at completely consistent picture of spatial Spin(3) structure of those spaces. We introduce new kinds of walls, called Bound State Transformation(BST) walls, in the moduli space across which the nature of BPS bound states changes but the index remains continuous. These walls are necessary to explain the continuity of BPS index. BPS states can undergo recombination, conjugation or hybrids of the two when crossing a BST wall. Conjugation phenomenon happens near singularities in the moduli space and we relate massless spectra of BPS states at such singularities to monodromies around them. In cases when massless vector BPS particles are present we find new constraints on the spectrum and in particular predict the existence of magnetic monopoles becoming massless at such singularities. We give a simple physical derivation of the Kontsevich-Soibelman wall-crossing formula. Considering galaxy-like configurations of BPS particles with a central supermassive black hole with a number of stellar BPS systems around it we derive a consistency requirement on the partition function of such BPS galaxies. This requirement turns out to be nothing but Kontsevich-Soibelman wall-crossing formula. Our approach gives a generalization of the formula for the case when massless BPS particles are present.

  9. Magnetospheric state of sawtooth events

    NASA Astrophysics Data System (ADS)

    Fung, Shing F.; Tepper, Julia A.; Cai, Xia

    2016-08-01

    Magnetospheric sawtooth events, first identified in the early 1990s, are named for their characteristic appearance of multiple quasiperiodic intervals of slow decrease followed by sharp increase of proton differential energy fluxes in the geosynchronous region. The successive proton flux oscillations have been interpreted as recurrences of stretching and dipolarization of the nightside geomagnetic field. Due to their often extended intervals with 2-10 cycles, sawteeth occurrences are sometimes referred to as a magnetospheric mode. While studies of sawtooth events over the past two decades have yielded a wealth of information about such events, the magnetospheric state conditions for the occurrence of sawtooth events and how sawtooth oscillations may depend on the magnetospheric state conditions remain unclear. In this study, we investigate the characteristic magnetospheric state conditions (specified by Psw interplanetary magnetic field (IMF) Btot, IMF Bz Vsw, AE, Kp and Dst, all time shifted with respect to one another) associated with the intervals before, during, and after sawteeth occurrences. Applying a previously developed statistical technique, we have determined the most probable magnetospheric states propitious for the development and occurrence of sawtooth events, respectively. The statistically determined sawtooth magnetospheric state has also been validated by using out-of-sample events, confirming the notion that sawtooth intervals might represent a particular global state of the magnetosphere. We propose that the "sawtooth state" of the magnetosphere may be a state of marginal stability in which a slight enhancement in the loading rate of an otherwise continuous loading process can send the magnetosphere into the marginally unstable regime, causing it to shed limited amount of energy quickly and return to the marginally stable regime with the loading process continuing. Sawtooth oscillations result as the magnetosphere switches between the marginally

  10. Magnetospheric State of Sawtooth Events

    NASA Technical Reports Server (NTRS)

    Fung, Shing F.; Tepper, Julia A.; Cai, Xia

    2016-01-01

    Magnetospheric sawtooth events, first identified in the early 1990s, are named for their characteristic appearance of multiple quasiperiodic intervals of slow decrease followed by sharp increase of proton differential energy fluxes in the geosynchronous region. The successive proton flux oscillations have been interpreted as recurrences of stretching and dipolarization of the nightside geomagnetic field. Due to their often extended intervals with 210 cycles, sawteeth occurrences are sometimes referred to as a magnetospheric mode. While studies of sawtooth events over the past two decades have yielded a wealth of information about such events, the magnetospheric state conditions for the occurrence of sawtooth events and how sawtooth oscillations may depend on the magnetospheric state conditions remain unclear. In this study, we investigate the characteristic magnetospheric state conditions (specified by Psw interplanetary magnetic field (IMF) Btot, IMF Bz Vsw, AE, Kp and Dst, all time shifted with respect to one another) associated with the intervals before, during, and after sawteeth occurrences. Applying a previously developed statistical technique, we have determined the most probable magnetospheric states propitious for the development and occurrence of sawtooth events, respectively. The statistically determined sawtooth magnetospheric state has also been validated by using out-of-sample events, confirming the notion that sawtooth intervals might represent a particular global state of the magnetosphere. We propose that the sawtooth state of the magnetosphere may be a state of marginal stability in which a slight enhancement in the loading rate of an otherwise continuous loading process can send the magnetosphere into the marginally unstable regime, causing it to shed limited amount of energy quickly and return to the marginally stable regime with the loading process continuing. Sawtooth oscillations result as the magnetosphere switches between the marginally

  11. High power solid state lasers

    SciTech Connect

    Weber, H.

    1988-01-01

    These proceedings discuss the following subjects: trends in materials processing with laser radiation; slabs and high power systems; glasses and new crystals; solid state lasers at HOYA Corp.; lamps, resonators and transmission; glasses as active materials for high average power solid state lasers; flashlamp pumped GGG-crystals; alexandrite lasers; designing telescope resonators; mode operation of neodymium: YAG lasers; intracavity frequency doubling with KTP crystal and thermal effects in cylinder lasers.

  12. Solid State Photovoltaic Research Branch

    SciTech Connect

    Not Available

    1990-09-01

    This report summarizes the progress of the Solid State Photovoltaic Research Branch of the Solar Energy Research Institute (SERI) from October 1, 1988, through September 30,l 1989. Six technical sections of the report cover these main areas of SERIs in-house research: Semiconductor Crystal Growth, Amorphous Silicon Research, Polycrystalline Thin Films, III-V High-Efficiency Photovoltaic Cells, Solid-State Theory, and Laser Raman and Luminescence Spectroscopy. Sections have been indexed separately for inclusion on the data base.

  13. 2007 Western States Fire Mission

    NASA Technical Reports Server (NTRS)

    Howell, Kathleen

    2008-01-01

    A general overview of the Ikhana Uninhabited Air System (UAS) is presented. The contents include: 1) Ikhana UAS; 2) Ikhana UAS / Ground Control Station (GCS); 3) Ikhana UAS / Antennas; 4) Western States Fire Mission 2007 Partners; 5) FAA Certificate of Authorization (COA); 6) Western States Fire Missions (WSFM) 2007; 7) WSFM 1-4 2007; 8) California Wildfire Emergency Response 2007; 9) WSFM 5-8 Emergency Response 2007; 10) WSFM Achievements; and 11) WSFM Challenges.

  14. Quantum coherence of steered states

    PubMed Central

    Hu, Xueyuan; Milne, Antony; Zhang, Boyang; Fan, Heng

    2016-01-01

    Lying at the heart of quantum mechanics, coherence has recently been studied as a key resource in quantum information theory. Quantum steering, a fundamental notion originally considered by Schödinger, has also recently received much attention. When Alice and Bob share a correlated quantum system, Alice can perform a local measurement to ‘steer’ Bob’s reduced state. We introduce the maximal steered coherence as a measure describing the extent to which steering can remotely create coherence; more precisely, we find the maximal coherence of Bob’s steered state in the eigenbasis of his original reduced state, where maximization is performed over all positive-operator valued measurements for Alice. We prove that maximal steered coherence vanishes for quantum-classical states whilst reaching a maximum for pure entangled states with full Schmidt rank. Although invariant under local unitary operations, maximal steered coherence may be increased when Bob performs a channel. For a two-qubit state we find that Bob’s channel can increase maximal steered coherence if and only if it is neither unital nor semi-classical, which coincides with the condition for increasing discord. Our results show that the power of steering for coherence generation, though related to discord, is distinct from existing measures of quantum correlation. PMID:26781214

  15. Quantum coherence of steered states.

    PubMed

    Hu, Xueyuan; Milne, Antony; Zhang, Boyang; Fan, Heng

    2016-01-19

    Lying at the heart of quantum mechanics, coherence has recently been studied as a key resource in quantum information theory. Quantum steering, a fundamental notion originally considered by Schödinger, has also recently received much attention. When Alice and Bob share a correlated quantum system, Alice can perform a local measurement to 'steer' Bob's reduced state. We introduce the maximal steered coherence as a measure describing the extent to which steering can remotely create coherence; more precisely, we find the maximal coherence of Bob's steered state in the eigenbasis of his original reduced state, where maximization is performed over all positive-operator valued measurements for Alice. We prove that maximal steered coherence vanishes for quantum-classical states whilst reaching a maximum for pure entangled states with full Schmidt rank. Although invariant under local unitary operations, maximal steered coherence may be increased when Bob performs a channel. For a two-qubit state we find that Bob's channel can increase maximal steered coherence if and only if it is neither unital nor semi-classical, which coincides with the condition for increasing discord. Our results show that the power of steering for coherence generation, though related to discord, is distinct from existing measures of quantum correlation.

  16. Steering Bell-diagonal states

    PubMed Central

    Quan, Quan; Zhu, Huangjun; Liu, Si-Yuan; Fei, Shao-Ming; Fan, Heng; Yang, Wen-Li

    2016-01-01

    We investigate the steerability of two-qubit Bell-diagonal states under projective measurements by the steering party. In the simplest nontrivial scenario of two projective measurements, we solve this problem completely by virtue of the connection between the steering problem and the joint-measurement problem. A necessary and sufficient criterion is derived together with a simple geometrical interpretation. Our study shows that a Bell-diagonal state is steerable by two projective measurements iff it violates the Clauser-Horne-Shimony-Holt (CHSH) inequality, in sharp contrast with the strict hierarchy expected between steering and Bell nonlocality. We also introduce a steering measure and clarify its connections with concurrence and the volume of the steering ellipsoid. In particular, we determine the maximal concurrence and ellipsoid volume of Bell-diagonal states that are not steerable by two projective measurements. Finally, we explore the steerability of Bell-diagonal states under three projective measurements. A simple sufficient criterion is derived, which can detect the steerability of many states that are not steerable by two projective measurements. Our study offers valuable insight on steering of Bell-diagonal states as well as the connections between entanglement, steering, and Bell nonlocality. PMID:26911250

  17. Distinguishability of generic quantum states

    NASA Astrophysics Data System (ADS)

    Puchała, Zbigniew; Pawela, Łukasz; Życzkowski, Karol

    2016-06-01

    Properties of random mixed states of dimension N distributed uniformly with respect to the Hilbert-Schmidt measure are investigated. We show that for large N , due to the concentration of measure, the trace distance between two random states tends to a fixed number D ˜=1 /4 +1 /π , which yields the Helstrom bound on their distinguishability. To arrive at this result, we apply free random calculus and derive the symmetrized Marchenko-Pastur distribution, which is shown to describe numerical data for the model of coupled quantum kicked tops. Asymptotic value for the root fidelity between two random states, √{F }=3/4 , can serve as a universal reference value for further theoretical and experimental studies. Analogous results for quantum relative entropy and Chernoff quantity provide other bounds on the distinguishablity of both states in a multiple measurement setup due to the quantum Sanov theorem. We study also mean entropy of coherence of random pure and mixed states and entanglement of a generic mixed state of a bipartite system.

  18. How State Governments Are Promoting Instructional Computing: A State-by-State Summary.

    ERIC Educational Resources Information Center

    Christen, Kate; Gladstone, Peggy

    1983-01-01

    A summary of each state's instructional computing requirements for students and teachers, and statewide microcomputer classroom use are presented in chart format. Funding information and additional comments are also included. (MBR)

  19. Cancer in Chuuk State, Federated States of Micronesia.

    PubMed

    Ichiho, Henry M; Gladu, Rebecca; Keybond, Kolid; Ruben, Kino

    2004-09-01

    The purpose of this study, funded by the National Cancer Institute, was to document the state of cancer awareness and services in Chuuk State, Federated States of Micronesia (FSM) and to begin to identify the need for cancer-care services. Findings suggest that cancer is the third-leading cause of death in Chuuk, yet cancer-related awareness, prevention, detection, and treatment services are limited. A number of needs were identified, and an action plan was developed based on five priority areas: 1) establishing a cancer registry; 2) improving ICD coding skills and knowledge; 3) increasing public awareness about cancer; 4) establishing an office dedicated to cancer; and 5) increasing screening of high-risk individuals.

  20. Interference and which-state information for nonorthogonal states

    NASA Astrophysics Data System (ADS)

    Fonseca-Romero, K. M.; de Oliveira, J. G. G.; Peixoto de Faria, J. G.; Nemes, M. C.

    2014-12-01

    In two-dimensional systems, predictability and visibility satisfy a complementarity relation, which has been generalized to bipartite systems by including the concurrence. We consider systems in which the two alternatives of a which-state experiment are nonorthogonal states and propose generalized measures of predictability and visibility. Criteria like symmetry under exchange of the alternatives, vanishing visibility when only one of the alternatives is present, and clear operational meaning, favor definitions of predictability and visibility which use a three-dimensional basis, previously employed in the unambiguous discrimination of nonorthogonal states. We derive generalized single-partite and bipartite complementarity relations and find that predictability and visibility do not exhaust the single-partite properties for a nonorthogonal basis. A recent experiment on the quantum-classical border is analyzed using generalized complementarity relations.

  1. Occupancy estimation and modeling with multiple states and state uncertainty

    USGS Publications Warehouse

    Nichols, J.D.; Hines, J.E.; MacKenzie, D.I.; Seamans, M.E.; Gutierrez, R.J.

    2007-01-01

    The distribution of a species over space is of central interest in ecology, but species occurrence does not provide all of the information needed to characterize either the well-being of a population or the suitability of occupied habitat. Recent methodological development has focused on drawing inferences about species occurrence in the face of imperfect detection. Here we extend those methods by characterizing occupied locations by some additional state variable ( e. g., as producing young or not). Our modeling approach deals with both detection probabilities,1 and uncertainty in state classification. We then use the approach with occupancy and reproductive rate data from California Spotted Owls (Strix occidentalis occidentalis) collected in the central Sierra Nevada during the breeding season of 2004 to illustrate the utility of the modeling approach. Estimates of owl reproductive rate were larger than naive estimates, indicating the importance of appropriately accounting for uncertainty in detection and state classification.

  2. Bound Anionic States of Aadenine

    SciTech Connect

    Haranczyk, Maciej; Gutowski, Maciej S.; Li, Xiang; Bowen, Kit H.

    2007-03-20

    The research described in this product was performed in part in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory. Anionic states of nucleic acid bases are involved in DNA damage by low-energy electrons and in charge transfer through DNA. Previous gas phase studies of free, unsolvated nucleic acid base parent anions probed only dipole-bound states, which are not present in condensed phase environments, but did not observe valence anionic states, which for purine bases are thought to be adiabatically unbound. Contrary to this expectation,wehave demonstrated that some thus far ignored tautomers of adenine, which result from enamine-imine transformations, support valence anionic states with electron vertical detachment energies as large as 2.2 eV, and at least one of these anionic tautomers is adiabatically bound. Moreover, we predict that the new anionic tautomers should also dominate in solutions and should be characterized by larger values of electron vertical detachment energy than the canonical valence anion. All of the newfound anionic tautomers might be formed in the course of dissociative electron attachment followed by a hydrogen atom attachment to a carbon atom, and they might affect the structure and properties of DNA and RNA exposed to low-energy electrons. The new valence states observed here, unlike the dipole-bound state, could exist in condensed phases and might be relevant to radiobiological damage. The discovery of these valence anionic states of adenine was facilitated by the development of (i) an experimental method for preparing parent anions of nucleic acid bases for photoelectron experiments, and (ii) a combinatorial/quantum chemical approach for identification of the most stable tautomers of organic molecules.

  3. Bound Anionic States of Adenine

    SciTech Connect

    Haranczyk, Maciej; Gutowski, Maciej S.; Li, Xiang; Bowen, Kit H.

    2007-03-20

    The research described in this product was performed in part in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory. Anionic states of nucleic acid bases are involved in DNA damage by low-energy electrons and in charge transfer through DNA. Previous gas phase studies of free, unsolvated nucleic acid base parent anions probed only dipole-bound states, which are not present in condensed phase environments, but did not observe valence anionic states, which for purine bases are thought to be adiabatically unbound. Contrary to this expectation, we have demonstrated that some thus far ignored tautomers of adenine, which result from enamine-imine transformations, support valence anionic states with electron vertical detachment energies as large as 2.2 eV, and at least one of these anionic tautomers is adiabatically bound. Moreover, we predict that the new anionic tautomers should also dominate in solutions and should be characterized by larger values of electron vertical detachment energy than the canonical valence anion. All of the newfound anionic tautomers might be formed in the course of dissociative electron attachment followed by a hydrogen atom attachment to a carbon atom, and they might affect the structure and properties of DNA and RNA exposed to low-energy electrons. The new valence states observed here, unlike the dipole-bound state, could exist in condensed phases and might be relevant to radiobiological damage. The discovery of these valence anionic states of adenine was facilitated by the development of (i) an experimental method for preparing parent anions of nucleic acid bases for photoelectron experiments, and (it) a combinatorial/quantum chemical approach for identification of the most stable tautomers of organic molecules.

  4. State electricity profiles, March 1999

    SciTech Connect

    1999-03-01

    Due to the role electricity plays in the Nation`s economic and social well-being, interested parties have been following the electric power industry`s transition by keeping abreast of the restructuring and deregulation events that are taking place almost daily. Much of the attention centers around the States and how they are restructuring the business of electricity supply within their respective jurisdictions. This report is designed to profile each State and the District of Columbia regarding not only their current restructuring activities, but also their electricity generation and concomitant statistics from 1986 through 1996. Included are data on a number of subject areas including generating capability, generation, revenues, fuel use, capacity factor for nuclear plants, retail sales, and pollutant emissions. Although the Energy Information Administration (EIA) publishes this type of information, there is a lack of a uniform overview for each individual State. This report is intended to help fill that gap and also to serve as a framework for more detailed studies. In addition to basic statistics in tables and graphs, a textual section is provided for each State, discussing some of the points relative to electricity production that are noteworthy in, or unique to, that particular State. Also, each State is ranked according to the place it holds, as compared to the rest of the states, in various relevant areas, such as its average price of electricity per kilowatthour, its population, and its emissions of certain atmospheric pollutants. The final chapter covers the Nation as a whole. 451 figs., 520 tabs.

  5. The state of amphibians in the United States

    USGS Publications Warehouse

    Muths, E.; Adams, M.J.; Grant, E.H.C.; Miller, D.; Corn, P.S.; Ball, L.C.

    2012-01-01

    More than 25 years ago, scientists began to identify unexplained declines in amphibian populations around the world. Much has been learned since then, but amphibian declines have not abated and the interactions among the various threats to amphibians are not clear. Amphibian decline is a problem of local, national, and international scope that can affect ecosystem function, biodiversity, and commerce. This fact sheet provides a snapshot of the state of the amphibians and introduces examples to illustrate the range of issues in the United States.

  6. Coal industry taxes: state-by-state guide

    SciTech Connect

    Sammons, D.

    1981-01-01

    This book describes the taxes levied on coal mining industries by each of the 26 coal-producing states in the US. Described are severance taxes, charter fees, permit fees, franchise taxes, income taxes, property taxes, sales taxes, use taxes, unemployment compensations, workmens compensation, utility taxes, inspection fees, motor fuel taxes, motor vehicle use taxes, message tax, local taxes, etc. The appendices contain the results of a study to translate the tax burden imposed by 21 states into a per-ton figure and a reprint of the US Supreme Court decision upholding Montana's 30% severance tax on coal. (CKK)

  7. State and Local Government Partnership

    SciTech Connect

    Barton, Alexander; Rinebold, Joel; Aresta, Paul

    2012-03-30

    The State and Local Government Partnership project has built relationships between the Department of Energy (DOE), regional states, and municipalities. CCAT implemented this project using a structure that included leadership by the DOE. Outreach was undertaken through collaborative meetings, workshops, and briefings; the development of technical models and local energy plans; support for state stakeholder groups; and implementation of strategies to facilitate the deployment of hydrogen and fuel cell technologies. The final guidance documents provided to stakeholders consisted of individual strategic state “Roadmaps” to serve as development plans. These “Roadmaps” confirm economic impacts, identify deployment targets, and compare policies and incentives for facility development in each of the regional states. The partnerships developed through this project have improved the exchange of knowledge between state and local government stakeholders and is expected to increase the deployment of hydrogen and fuel cell technologies in early market applications, consistent with the DOE’s market transformation efforts. Technically accurate and objective information was, and continues to be, provided to improve public and stakeholder perceptions regarding the use of hydrogen and fuel cell technologies. Based on the “Roadmaps” and studies conducted for this project, there is the potential to generate approximately 10.75 million megawatt hours (MWh) of electricity annually from hydrogen and fuel cell technologies at potential host sites in the Northeast regional states, through the development of 1,364 to 1,818 megawatts (MW) of fuel cell electric generation capacity. Currently, the region has approximately 1,180 companies that are part of the growing hydrogen and fuel cell industry supply chain in the region. These companies are estimated to have over $1 billion in annual revenue and investment, contribute more than $51 million in annual state and local tax revenue

  8. Regional and State Level Water Scarcity Report: Northeast United States

    NASA Astrophysics Data System (ADS)

    Nicoletti, C. K.; Lopez-Morales, C. A.; Hoover, J. H.; Voigt, B. G.; Vorosmarty, C. J.; Mohammed, I. N.

    2010-12-01

    There are an abundance of large-scale, coarse resolution global water scarcity studies, but the existing literature fails to address regional and state specific scarcity measures. Moreover, while environmental water requirements are an integral factor in the development and implementation of sustainable water management practices, only recently has this notion been introduced to water scarcity research. In this paper, we argue that developing a preliminary measure of water scarcity, at the regional and state levels, will allow for more informed policy development. The goal of this study is to generate a more comprehensive understanding of water scarcity in the Northeast, by gathering fine scale data, applying a consistent methodology to the calculation of a scarcity index, and analyzing the results to see relative trends in spatio-temporal water scarcity. Public supply, irrigation, rural, industrial and thermo-power withdrawals have been compiled from USGS state water use publications from 1950 to 1985. Using the WBMplus water model runoff data, state specific in-stream environmental water requirements were calculated using the accepted hydro-ecological methodology. Water scarcity was then calculated as a ratio of water withdrawals to total available water minus environmental flow requirements for the system. In so doing, this study generates a spatially explicit and temporally varying water scarcity indicator (WSI) for the Northeastern United States between 1950 and 2000 at the regional and state levels at a five-year time interval. Calculation of a spatial and temporal water scarcity indicator enabled us to identify regions and specific states that were: slightly exploited (WSI < 0.3), moderately exploited (0.31.0). The minimum environmental water requirements to maintain in-stream aquatic and riparian ecosystems for the Northeastern states ranged between 27.5 to 36.3 percent of the mean annual

  9. Passive states for essential observers

    NASA Astrophysics Data System (ADS)

    Strich, Robert

    2008-02-01

    The aim of this note is to present a unified approach to the results given by Borchers and Buchholz ["Global properties of vacuum states in de Sitter space," Ann. Inst. Henri Poincare, Sect. A. 70, 23-40 (1999)] and by Buchholz and Summers ["Stable quantum systems in anti-de Sitter space: Causality, independence and spectral properties," J. Math. Phys. 45, 4810-4831 (2004)] which also covers examples of models not presented in these two papers (e.g., d-dimensional Minkowski space-time for d ⩾3). Assuming that a state is passive for an observer traveling along certain (essential) worldlines, we show that this state is invariant under the isometry group, is a temperature equilibrium state for the observer at a temperature uniquely determined by the structure constants of the Lie algebra involved, and fulfills (a variant of) the Reeh-Schlieder property. Also, the modular objects associated with such a state and the observable algebra of an observer are computed and a version of weak locality is examined.

  10. Passive states for essential observers

    SciTech Connect

    Strich, Robert

    2008-02-15

    The aim of this note is to present a unified approach to the results given by Borchers and Buchholz ['Global properties of vacuum states in de Sitter space', Ann. Inst. Henri Poincare, Sect. A. 70, 23-40 (1999)] and by Buchholz and Summers ['Stable quantum systems in anti-de Sitter space: Causality, independence and spectral properties', J. Math. Phys. 45, 4810-4831 (2004)] which also covers examples of models not presented in these two papers (e.g., d-dimensional Minkowski space-time for d{>=}3). Assuming that a state is passive for an observer traveling along certain (essential) worldlines, we show that this state is invariant under the isometry group, is a temperature equilibrium state for the observer at a temperature uniquely determined by the structure constants of the Lie algebra involved, and fulfills (a variant of) the Reeh-Schlieder property. Also, the modular objects associated with such a state and the observable algebra of an observer are computed and a version of weak locality is examined.

  11. Thermodynamic States in Explosion Fields

    SciTech Connect

    Kuhl, A L

    2010-03-12

    We investigate the thermodynamic states occurring in explosion fields from condensed explosive charges. These states are often modeled with a Jones-Wilkins-Lee (JWL) function. However, the JWL function is not a Fundamental Equation of Thermodynamics, and therefore cannot give a complete specification of such states. We use the Cheetah code of Fried to study the loci of states of the expanded detonation products gases from C-4 charges, and their combustion products air. In the Le Chatelier Plane of specific-internal-energy versus temperature, these loci are fit with a Quadratic Model function u(T), which has been shown to be valid for T < 3,000 K and p < 1k-bar. This model is used to derive a Fundamental Equation u(v,s) for C-4. Given u(v,s), one can use Maxwell's Relations to derive all other thermodynamic functions, such as temperature: T(v,s), pressure: p(v,s), enthalpy: h(v,s), Gibbs free energy: g(v,s) and Helmholz free energy: f(v,s); these loci are displayed in figures for C-4. Such complete equations of state are needed for numerical simulations of blast waves from explosive charges, and their reflections from surfaces.

  12. Linearized theory of peridynamic states.

    SciTech Connect

    Silling, Stewart Andrew

    2009-04-01

    A state-based peridynamic material model describes internal forces acting on a point in terms of the collective deformation of all the material within a neighborhood of the point. In this paper, the response of a state-based peridynamic material is investigated for a small deformation superposed on a large deformation. The appropriate notion of a small deformation restricts the relative displacement between points, but it does not involve the deformation gradient (which would be undefined on a crack). The material properties that govern the linearized material response are expressed in terms of a new quantity called the modulus state. This determines the force in each bond resulting from an incremental deformation of itself or of other bonds. Conditions are derived for a linearized material model to be elastic, objective, and to satisfy balance of angular momentum. If the material is elastic, then the modulus state is obtainable from the second Frechet derivative of the strain energy density function. The equation of equilibrium with a linearized material model is a linear Fredholm integral equation of the second kind. An analogue of Poincare's theorem is proved that applies to the infinite dimensional space of all peridynamic vector states, providing a condition similar to irrotationality in vector calculus.

  13. Multipartite entanglement in conditional states

    NASA Astrophysics Data System (ADS)

    Urbina, Juan Diego; Strunz, Walter T.; Viviescas, Carlos

    2013-02-01

    A key lesson of the decoherence program is that information flowing out from an open system is stored in the quantum state of the surroundings. Simultaneously, quantum measurement theory shows that the evolution of any open system when its environment is measured is nonlinear and leads to pure states conditioned on the measurement record. Here we report the discovery of a fundamental relation between measurement and entanglement which is characteristic of this scenario. It takes the form of a scaling law between the amount of entanglement in the conditional state of the system and the probabilities of the experimental outcomes obtained from measuring the state of the environment, with the latter modeled as a bosonic field linearly coupled with the system. Using the scaling, we construct the distribution of entanglement over the ensemble of experimental outcomes for standard models with one open channel and provide rigorous results on finite-time disentanglement in systems coupled to non-Markovian baths. In principle, the scaling allows the direct experimental detection and quantification of entanglement in conditional states of a large class of open systems by quantum tomography of the bath even when it consists of a single mode.

  14. Antiferromagnetic state in bilayer graphene

    NASA Astrophysics Data System (ADS)

    Kharitonov, Maxim

    2012-11-01

    Motivated by the recent experiment of Velasco Jr. [J. Velasco Jr. , Nat. Nanotechnology1748-338710.1038/nnano.2011.251 7, 156 (2012)], we develop a mean-field theory of the interaction-induced antiferromagnetic (AF) state in bilayer graphene at charge neutrality point at arbitrary perpendicular magnetic field B. We demonstrate that the AF state can persist at all B. At higher B, the state continuously crosses over to the AF phase of the ν=0 quantum Hall ferromagnet, recently argued to be realized in the insulating ν=0 state. The mean-field quasiparticle gap is finite at B=0 and grows with increasing B, becoming quasilinear in the quantum Hall regime, in accord with the reported behavior of the transport gap. By adjusting the two free parameters of the model, we obtain a simultaneous quantitative agreement between the experimental and theoretical values of the key parameters of the gap dependence—its zero-field value and slope at higher fields. Our findings suggest that the insulating state observed in bilayer graphene in Ref. is antiferromagnetic (canted, once the Zeeman effect is taken into account) at all magnetic fields.

  15. Classical simulation of entangled states

    NASA Astrophysics Data System (ADS)

    Bharath, H. M.; Ravishankar, V.

    2014-06-01

    Characterization of nonclassicality or quantumness of a state is fundamental to foundations of quantum mechanics and quantum information. At the heart of the problem is the question whether there exist classical systems—howsoever complicated—that can mimic a given quantum state. Whilst this has been traditionally addressed through the violation of Bell inequality or nonseparability, we show that it is possible to go beyond them, by introducing the concept of classical simulation. Focusing on the two-qubit case, we show that, while for pure states, classical simulability is equivalent to existence of a local hidden variable (LHV) model, the conditions for simulability can be weaker for mixed states, demanding what we call only a generalized LHV description. Consequently, quantum states which defy a classical simulation—which we call exceptional—may require conditions which are more stringent than violation of Bell inequalities. We illustrate these features with a number of representative examples and discuss the underlying reasons, by employing fairly simple arguments.

  16. Squeezed States in Josephson Junctions.

    NASA Astrophysics Data System (ADS)

    Hu, X.; Nori, F.

    1996-03-01

    We have studied quantum fluctuation properties of Josephson junctions in the limit of large Josephson coupling energy and small charging energy, when the eigenstates of the system can be treated as being nearly localized. We have considered(X. Hu and F. Nori, preprints.) a Josephson junction in a variety of situations, e.g., coupled to one or several of the following elements: a capacitor, an inductor (in a superconducting ring), and an applied current source. By solving an effective Shrödinger equation, we have obtained squeezed vacuum (coherent) states as the ground states of a ``free-oscillating'' (linearly-driven) Josephson junction, and calculated the uncertainties of its canonical momentum, charge, and coordinate, phase. We have also shown that the excited states of the various systems we consider are similar to the number states of a simple harmonic oscillator but with different fluctuation properties. Furthermore, we have obtained the time-evolution operators for these systems. These operators can make it easier to calculate the time-dependence of the expectation values and fluctuations of various quantities starting from an arbitrary initial state.

  17. Thermodynamic States in Explosion Fields

    SciTech Connect

    Kuhl, A L

    2009-10-16

    Here we investigate the thermodynamic states occurring in explosion fields from the detonation of condensed explosives in air. In typical applications, the pressure of expanded detonation products gases is modeled by a Jones-Wilkins-Lee (JWL) function: P{sub JWL} = f(v,s{sub CJ}); constants in that function are fit to cylinder test data. This function provides a specification of pressure as a function of specific volume, v, along the expansion isentrope (s = constant = s{sub CJ}) starting at the Chapman-Jouguet (CJ) state. However, the JWL function is not a fundamental equation of thermodynamics, and therefore gives an incomplete specification of states. For example, explosions inherently involve shock reflections from surfaces; this changes the entropy of the products, and in such situations the JWL function provides no information on the products states. In addition, most explosives are not oxygen balanced, so if hot detonation products mix with air, they after-burn, releasing the heat of reaction via a turbulent combustion process. This raises the temperature of explosion products cloud to the adiabatic flame temperature ({approx}3,000K). Again, the JWL function provides no information on the combustion products states.

  18. Cavity-state preparation using adiabatic transfer

    NASA Astrophysics Data System (ADS)

    Larson, Jonas; Andersson, Erika

    2005-05-01

    We show how to prepare a variety of cavity field states for multiple cavities. The state preparation technique used is related to the method of stimulated adiabatic Raman passage. The cavity modes are coupled by atoms, making it possible to transfer an arbitrary cavity field state from one cavity to another and also to prepare nontrivial cavity field states. In particular, we show how to prepare entangled states of two or more cavities, such as an Einstein-Podolsky-Rosen state and a W state, as well as various entangled superpositions of coherent states in different cavities, including Schrödinger cat states. The theoretical considerations are supported by numerical simulations.

  19. 11 CFR 9032.11 - State.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false State. 9032.11 Section 9032.11 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL ELECTION CAMPAIGN FUND: PRESIDENTIAL PRIMARY MATCHING FUND DEFINITIONS § 9032.11 State. State means each State of the United States, Puerto Rico,...

  20. Common Core State Standards: I Wonder?

    ERIC Educational Resources Information Center

    Tienken, Christopher H.

    2010-01-01

    On June 1, 2009, the National Governors Association Center for Best Practices (NGA Center) and the Council of Chief State School Officers (CCSSO) issued a press release stating that 49 states and territories had joined the Common Core State Standards Initiative (CCSS). That initiative proposed that all states voluntarily adopt the same set of…

  1. 22 CFR 96.30 - State licensing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Licensing and Corporate Governance § 96.30 State licensing. (a) The agency or person is properly licensed or otherwise authorized by State law to provide adoption services in at least one State. (b) The agency or... persons that are licensed or authorized by State law to provide adoption services in that State and...

  2. 22 CFR 96.30 - State licensing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Licensing and Corporate Governance § 96.30 State licensing. (a) The agency or person is properly licensed or otherwise authorized by State law to provide adoption services in at least one State. (b) The agency or... persons that are licensed or authorized by State law to provide adoption services in that State and...

  3. 22 CFR 135.11 - State plans.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Relations DEPARTMENT OF STATE MISCELLANEOUS UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE... its own language to the extent permitted by law. (d) Amendments. A State will amend a plan whenever... State law, organization, policy, or State agency operation. The State will obtain approval for...

  4. 50 CFR 253.22 - State projects.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false State projects. 253.22 Section 253.22... State projects. (a) General—(1) Designation of state agency. The Governor of each state shall notify the... participation under the Act, to sign project documents, and to receive payments. (2) States that choose...

  5. State Constitutional Law: Teaching and Scholarship.

    ERIC Educational Resources Information Center

    Williams, Robert F.

    1991-01-01

    State constitutional law is an emerging area for legal education, partly because of state supreme court decisions relying on state rather than federal constitutional law. Studying state constitutional law highlights similarities and diversity of legal and governmental systems. Interest in establishment of curricula and materials in state law is…

  6. 34 CFR 84.665 - State.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false State. 84.665 Section 84.665 Education Office of the Secretary, Department of Education GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 84.665 State. State means any of the States of the United States, the District of Columbia,...

  7. 22 CFR 1509.665 - State.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true State. 1509.665 Section 1509.665 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.665 State. State means any of the States of the United States, the District...

  8. 22 CFR 1509.665 - State.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false State. 1509.665 Section 1509.665 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.665 State. State means any of the States of the United States, the District...

  9. 22 CFR 1509.665 - State.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true State. 1509.665 Section 1509.665 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.665 State. State means any of the States of the United States, the District...

  10. 22 CFR 1509.665 - State.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true State. 1509.665 Section 1509.665 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.665 State. State means any of the States of the United States, the District...

  11. 22 CFR 210.665 - State.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false State. 210.665 Section 210.665 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 210.665 State. State means any of the States of the United States,...

  12. 28 CFR 65.2 - State Government.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false State Government. 65.2 Section 65.2... Eligible Applicants § 65.2 State Government. In the event that a law enforcement emergency exists throughout a state or part of a state, a state (on behalf of itself or a local unit of government) may...

  13. 28 CFR 65.2 - State Government.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false State Government. 65.2 Section 65.2... Eligible Applicants § 65.2 State Government. In the event that a law enforcement emergency exists throughout a state or part of a state, a state (on behalf of itself or a local unit of government) may...

  14. 28 CFR 65.2 - State Government.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false State Government. 65.2 Section 65.2... Eligible Applicants § 65.2 State Government. In the event that a law enforcement emergency exists throughout a state or part of a state, a state (on behalf of itself or a local unit of government) may...

  15. 28 CFR 65.2 - State Government.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false State Government. 65.2 Section 65.2... Eligible Applicants § 65.2 State Government. In the event that a law enforcement emergency exists throughout a state or part of a state, a state (on behalf of itself or a local unit of government) may...

  16. 28 CFR 65.2 - State Government.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false State Government. 65.2 Section 65.2... Eligible Applicants § 65.2 State Government. In the event that a law enforcement emergency exists throughout a state or part of a state, a state (on behalf of itself or a local unit of government) may...

  17. 22 CFR 210.665 - State.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false State. 210.665 Section 210.665 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 210.665 State. State means any of the States of the United States,...

  18. 22 CFR 1509.665 - State.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true State. 1509.665 Section 1509.665 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.665 State. State means any of the States of the United States, the District...

  19. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures...

  20. 7 CFR 1250.308 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1250.308 Section 1250.308 Agriculture... Research and Promotion Order Definitions § 1250.308 United States. United States means the 48 contiguous States of the United States of America and the District of Columbia....

  1. 7 CFR 1214.24 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1214.24 Section 1214.24 Agriculture... United States. United States means collectively the 50 states, the District of Columbia, the Commonwealth of Puerto Rico, and the territories and possessions of the United States. Christmas Tree...

  2. 7 CFR 1250.308 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false United States. 1250.308 Section 1250.308 Agriculture... Research and Promotion Order Definitions § 1250.308 United States. United States means the 48 contiguous States of the United States of America and the District of Columbia....

  3. 7 CFR 1219.26 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1219.26 Section 1219.26 Agriculture..., AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.26 United States. United States means collectively the several 50 States of the United States, the District...

  4. 7 CFR 1219.26 - United States.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false United States. 1219.26 Section 1219.26 Agriculture..., AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.26 United States. United States means collectively the several 50 States of the United States, the District...

  5. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures...

  6. 22 CFR 120.13 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false United States. 120.13 Section 120.13 Foreign... United States. United States, when used in the geographical sense, includes the several states, the Commonwealth of Puerto Rico, the insular possessions of the United States, the District of Columbia,...

  7. 75 FR 5373 - United States Mint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... United States Mint ACTION: Notification of Pricing for 2010 United States Mint Presidential $1 Coin Proof Set. \\TM\\ SUMMARY: The United States Mint is announcing the price of the 2010 United States Mint Presidential $1 Coin Proof Set. The 2010 United States Mint Presidential $1 Coin Proof Set, featuring $1...

  8. 22 CFR 120.13 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false United States. 120.13 Section 120.13 Foreign... United States. United States, when used in the geographical sense, includes the several states, the Commonwealth of Puerto Rico, the insular possessions of the United States, the District of Columbia,...

  9. 7 CFR 1219.26 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1219.26 Section 1219.26 Agriculture..., AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.26 United States. United States means collectively the several 50 States of the United States, the District...

  10. 7 CFR 1205.313 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1205.313 Section 1205.313 Agriculture... Research and Promotion Order Definitions § 1205.313 United States. United States means the 50 States of the United States of America....

  11. 7 CFR 1150.106 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 9 2011-01-01 2011-01-01 false United States. 1150.106 Section 1150.106 Agriculture... Order Definitions § 1150.106 United States. United States means the 48 contiguous States in the continental United States....

  12. 7 CFR 1205.313 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false United States. 1205.313 Section 1205.313 Agriculture... Research and Promotion Order Definitions § 1205.313 United States. United States means the 50 States of the United States of America....

  13. 22 CFR 120.13 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false United States. 120.13 Section 120.13 Foreign... United States. United States, when used in the geographical sense, includes the several states, the Commonwealth of Puerto Rico, the insular possessions of the United States, the District of Columbia,...

  14. 22 CFR 120.13 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false United States. 120.13 Section 120.13 Foreign... United States. United States, when used in the geographical sense, includes the several states, the Commonwealth of Puerto Rico, the insular possessions of the United States, the District of Columbia,...

  15. 7 CFR 60.127 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false United States. 60.127 Section 60.127 Agriculture... FOR FISH AND SHELLFISH General Provisions Definitions § 60.127 United States. United States means the... the United States, and the waters of the United States as defined in § 60.132....

  16. 7 CFR 60.127 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false United States. 60.127 Section 60.127 Agriculture... FOR FISH AND SHELLFISH General Provisions Definitions § 60.127 United States. United States means the... the United States, and the waters of the United States as defined in § 60.132....

  17. 7 CFR 1219.26 - United States.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false United States. 1219.26 Section 1219.26 Agriculture..., AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.26 United States. United States means collectively the several 50 States of the United States, the District...

  18. 7 CFR 1250.308 - United States.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1250.308 Section 1250.308 Agriculture... Research and Promotion Order Definitions § 1250.308 United States. United States means the 48 contiguous States of the United States of America and the District of Columbia....

  19. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures...

  20. 7 CFR 1205.23 - United States.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false United States. 1205.23 Section 1205.23 Agriculture... Procedures for Conduct of Sign-up Period Definitions § 1205.23 United States. The term United States means the 50 states of the United States of America. Procedures...