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Sample records for 4355a peruvian soil-1

  1. Ultra-low level plutonium isotopes in the NIST SRM 4355A (Peruvian Soil-1).

    PubMed

    Inn, Kenneth G W; LaRosa, Jerome; Nour, Svetlana; Brooks, George; LaMont, Steve; Steiner, Rob; Williams, Ross; Patton, Brad; Bostick, Debbie; Eiden, Gregory; Petersen, Steve; Douglas, Matthew; Beals, Donna; Cadieux, James; Hall, Greg; Goldberg, Steve; Vogt, Stephan

    2009-05-01

    For more than 20 years, countries and their agencies which monitor radionuclide discharge sites and storage facilities have relied on the National Institute of Standards and Technology (NIST) Standard Reference Material (SRM) 4355 Peruvian Soil. Its low fallout contamination makes it an ideal soil blank for measurements associated with terrestrial-pathway-to-man studies. Presently, SRM 4355 is out of stock, and a new batch of the Peruvian soil is currently under development as future NIST SRM 4355A. Both environmental radioanalytical laboratories and mass spectrometry communities will benefit from the use of this SRM. The former must assess their laboratory procedural contamination and measurement detection limits by measurement of blank sample material. The Peruvian Soil is so low in anthropogenic radionuclide content that it is a suitable virtual blank. On the other hand, mass spectrometric laboratories have high sensitivity instruments that are capable of quantitative isotopic measurements at low plutonium levels in the SRM 4355 (first Peruvian Soil SRM) that provided the mass spectrometric community with the calibration, quality control, and testing material needed for methods development and legal defensibility. The quantification of the ultra-low plutonium content in the SRM 4355A was a considerable challenge for the mass spectrometric laboratories. Careful blank control and correction, isobaric interferences, instrument stability, peak assessment, and detection assessment were necessary. Furthermore, a systematic statistical evaluation of the measurement results and considerable discussions with the mass spectroscopy metrologists were needed to derive the certified values and uncertainties. The one sided upper limit of the 95% tolerance with 95% confidence for the massic (239)Pu content in SRM 4355A is estimated to be 54,000 atoms/g.

  2. Peruvian Moche Jewelry.

    ERIC Educational Resources Information Center

    Patterson, Berniece

    1998-01-01

    Surveys the history of the pre-Columbian, Peruvian Moche art, particularly the ornamental jewelry found in Moche burial sites. Outlines a procedure for creating pins reminiscent of Moche jewelry out of paper and other inexpensive materials. Points to ways that the lesson can be combined with lessons in history and science. (DSK)

  3. Peruvian villages go solar

    SciTech Connect

    Duffy, J.

    1999-12-01

    Students and faculty from an American University work with indigenous Peruvians to electrify their village and improve their quality of life. The remote village of Malvas in the Andes seems typical of many in Peru. The 500 Inca descendants have no electricity, no running water, one telephone and mud adobe houses. At a 10,000-foot (3,048 m) altitude, residents survive through subsistence farming. And this project might sound like a typical solar system installation--a system is donated, consultants install it, no one owns it and if something goes wrong, no one fixes it. The equipment ultimately helps no one and few learn from the experience. But two aspects of this project make it unique - the unusual level of communal sharing in the town and the design and installation of the solar system by students.

  4. Native Communities and the Peruvian Constitutional Assembly

    ERIC Educational Resources Information Center

    American Indian Journal, 1978

    1978-01-01

    A loosely knit coalition of over 25 native groups, the Peruvian Amazon Peoples has prepared a statement directed at the Peruvian Constitutional Assembly for purposes of Native input into the preparation of a revised national constitution. (JC)

  5. Ubinas Volcano Activity in Peruvian Andes

    NASA Image and Video Library

    2014-05-01

    On April 28, 2014, NASA Terra spacecraft spotted signs of activity at Ubinas volcano in the Peruvian Andes. The appearance of a new lava dome in March 2014 and frequent ash emissions are signs of increasing activity at this volcano.

  6. Intestinal helminths in wild Peruvian red uakari monkeys (Cacajao calvus ucayalii) in the northeastern Peruvian Amazon.

    PubMed

    Conga, David F; Bowler, Mark; Tantalean, Manuel; Montes, Daniel; Serra-Freire, Nicolau Maués; Mayor, Pedro

    2014-04-01

    Parasites are important in the management of the health of primate populations. We examined 36 fecal samples from Peruvian red uakari monkeys (Cacajao calvus ucayalii) collected from wild animals in the northeastern Peruvian Amazon. Samples were positive for helminth infection. Nematodes egg: Strongyloididae, Trypanoxyuris sp., Spirurid, and a cestode egg were identified.

  7. The first meeting of Peruvian women physicists

    NASA Astrophysics Data System (ADS)

    Loayza, María Luisa Cerón

    2015-12-01

    The First Meeting of Peruvian Women Physicists helped bring together women physicists from different universities, especially from regions in the interior of Peru. Our initial statistical analysis about women entering and completing their undergraduate and graduate studies in Peruvian universities showed a low participation of women in study programs in physics. This situation motivated us to discuss this and propose solutions. In this First Meeting it was possible to broaden our vision of the problems that are common to women in the context of our social reality. We feel we have the strength and will continue working to improve this situation for the benefit of future generations.

  8. Bilingual Education: An Experience in Peruvian Amazonia.

    ERIC Educational Resources Information Center

    Larson, Mildred L., Ed.; Davis, Patricia M., Ed.

    This book reports on an experimental bilingual education program conducted in Peru by Peruvian educators and Summer Institute of Linguistics (SIL) linguists. Sections of the book discuss: (1) the historical perspective of the program; (2) program aspects such as teacher training, goals, and curriculum; (3) what this program may contribute to the…

  9. Evaluating the Peruvian Rural Communication Services Project.

    ERIC Educational Resources Information Center

    Mayo, John

    1988-01-01

    Reviews the Peruvian Rural Communication Services (PRCS) Project and outlines selected findings. Topics discussed include a brief description of Peru's economic and social conditions; satellite communication systems; audio teleconferencing; telephone service; planning and administration; research design features; data collection; and project…

  10. Contact dermatitis due to Alstroemeria (Peruvian lily).

    PubMed

    Apted, J H

    1990-01-01

    Two cases of hand dermatitis due to contact with the plant Alstroemeria (Peruvian Lily) are recorded. This plant has been increasingly used for making floral decorations during the last decade. As it is available throughout the year in Victoria more cases are likely to be discovered in the community.

  11. Investment opportunities in the Peruvian oil indusry

    SciTech Connect

    Zuniga, E.

    1993-12-31

    Investment opportunities in the Peruvian oil industry are discussed. The following topics are discussed: historical highlights; sedimentary basins currently available; renewed investment climate; need for oil exploration investment; petroperu`s privatization; global strategy for the sale of petroperu; petroperu`s main assets; and financial profile.

  12. Peruvian Higher Education: Expansions Amid Economic Crisis.

    ERIC Educational Resources Information Center

    Post, David

    1991-01-01

    Development of the Peruvian university system is described, focusing on periods of rapid expansion. Enrollment declines in 1974-78 are analyzed in the context of the educational reform program of the military government. The 1983 new university law, following return to civilian government, and future prospects for higher education are discussed.…

  13. Evaluating the Peruvian Rural Communication Services Project.

    ERIC Educational Resources Information Center

    Mayo, John

    1988-01-01

    Reviews the Peruvian Rural Communication Services (PRCS) Project and outlines selected findings. Topics discussed include a brief description of Peru's economic and social conditions; satellite communication systems; audio teleconferencing; telephone service; planning and administration; research design features; data collection; and project…

  14. Attitudes and values of Peruvian coca growers.

    PubMed

    Rojas, Maritza R

    2002-01-01

    This study uses semi-structured interviews to examine the attitudes and values of Peruvian coca growers toward coca leaf and cocaine basic paste (CBP) consumption and its distribution. The subjects of the study were 186 coca growers from Peruvian jungle valleys who are involved in illegal commercialization of coca leaf and cocaine paste production. Data collected in 1994 reveal that growers consider coca leaf to be a most profitable product and a unique opportunity to improve their quality of life. Although growers acknowledge that a problem exists among local users, they do not assume any responsibility for CBP consumption and dissemination in rural areas. This leads to the conclusion that awareness of a CBP consumption problem is not enough for growers to stop drug production; they need consistent training in social values, as well as support in legal and economic alternatives.

  15. Peruvian Rural School Construction System. SERP 71: Sierra Type.

    ERIC Educational Resources Information Center

    Cangiano, Miguel

    Based on cooperative action of the government and local communities, the Peruvian Rural School System (SERP 71) evolved from the necessity to reconstruct Peruvian schools of the Sierra region after the earthquake of 1970, and from Peru's new educational reform law (1970) which called for an active-dynamic pupil attitude, continuous updating of…

  16. Series of disasters strikes Peruvian Observatory

    NASA Astrophysics Data System (ADS)

    Scanlon, Jim

    A midday blaze severely damaged the Geophysical Observatory at Huancayo, Peru, high in the Andes above Lima on August 28, 1996. The fire, which started accidentally, was one of a series of misfortunes suffered by the Peruvian Geophysical Institute (IGP) in recent years.The observatory, which was built in 1919 by the Carnegie Institution of Washington, is a 4-hour drive by bus from the Pacific coast between cosmopolitan Lima and the Amazonian lowlands. From the late 1980s until 1992, the observatory was isolated from the international community due to political developments in Peru, namely the Maoist Communist insurrection known as Sendero Luminoso. The turmoil resulted in the loss of nearly all cooperative contracts with American universities for research at Huancayo. IGP did maintain a few contracts, such as one with Cornell for the Radio Observatory at Jicamarca in the northern part of the country.

  17. Geochemistry of Peruvian near-surface sediments

    NASA Astrophysics Data System (ADS)

    Böning, Philipp; Brumsack, Hans-Jürgen; Böttcher, Michael E.; Schnetger, Bernhard; Kriete, Cornelia; Kallmeyer, Jens; Borchers, Sven Lars

    2004-11-01

    Sixteen short sediment cores were recovered from the upper edge (UEO), within (WO) and below (BO) the oxygen minimum zone (OMZ) off Peru during cruise 147 of R/V Sonne. Solids were analyzed for major/trace elements, total organic carbon, total inorganic carbon, total sulfur, the stable sulfur isotope composition (δ 34S) of pyrite, and sulfate reduction rates (SRR). Pore waters were analyzed for dissolved sulfate/sulfide and δ 34S of sulfate. In all cores highest SRR were observed in the top 5 cm where pore water sulfate concentrations varied little due to resupply of sulfate by sulfide oxidation and/or diffusion of sulfate from bottom water. δ 34S of dissolved sulfate showed only minor downcore increases. Strong 32S enrichments in sedimentary pyrite (to -48‰ vs. V-CDT) are due to processes in the oxidative part of the sulfur cycle in addition to sulfate reduction. Manganese and Co are significantly depleted in Peruvian upwelling sediments most likely due to mobilization from particles settling through the OMZ, whereas release of both elements from reducing sediments only seems to occur in near-coastal sites. Cadmium, Mo and Re are exceptionally enriched in WO sediments (<600 m water depth). High Re and moderate Cd and Mo enrichments are seen in BO sediments (>600 m water depth). Re/Mo ratios indicate anoxic and suboxic conditions for WO and BO sediments, respectively. Cadmium and Mo downcore profiles suggest considerable contribution to UEO/WO sediments by a biodetrital phase, whereas Re presumably accumulates via diffusion across the sediment-water interface to precipitation depth. Uranium is distinctly enriched in WO sediments (due to sulfidic conditions) and in some BO sediments (due to phosphorites). Silver transfer to suboxic BO sediments is likely governed by diatomaceous matter input, whereas in anoxic WO sediments Ag is presumably trapped due to sulfide precipitation. Cadmium, Cu, Zn, Ni, Cr, Ag, and T1 predominantly accumulate via biogenic pre

  18. Mitochondrial DNA analysis of ancient Peruvian highlanders.

    PubMed

    Shinoda, Ken-ichi; Adachi, Noboru; Guillen, Sonia; Shimada, Izumi

    2006-09-01

    Ancient DNA recovered from 57 individuals excavated by Hiram Bingham at the rural communities of Paucarcancha, Patallacta, and Huata near the famed Inca royal estate and ritual site of Machu Picchu was analyzed by polymerase chain reaction, and the results were compared with ancient and modern DNA from various Central Andean areas to test their hypothesized indigenous highland origins. The control and coding regions of the mitochondrial DNA (mtDNA) of 35 individuals in this group were sequenced, and the haplogroups of each individual were determined. The frequency data for the haplogroups of these samples show clear proximity to those of modern Quechua and Aymara populations in the Peruvian and Bolivian highlands, and contrast with those of pre-Hispanic individuals of the north coast of Peru that we defined previously. Our study suggests a strong genetic affinity between sampled late pre-Hispanic individuals and modern Andean highlanders. A previous analysis of the Machu Picchu osteological collection suggests that the residents there were a mixed group of natives from various coastal and highland regions relocated by the Inca state for varied purposes. Overall, our study indicates that the sampled individuals from Paucarcancha and Patallacta were indigenous highlanders who provided supportive roles for nearby Machu Picchu. 2006 Wiley-Liss, Inc.

  19. Diagnosis of Cystic Echinococcosis, Central Peruvian Highlands

    PubMed Central

    Gonzalez, Armando E.; Zhang, Wenbao; McManus, Donald P.; Lopera, Luis; Ninaquispe, Berenice; Garcia, Hector H.; Rodríguez, Silvia; Verastegui, Manuela; Calderon, Carmen; Pan, William K.Y.; Gilman, Robert H.

    2008-01-01

    We evaluated prevalence of cystic echinococcosis (CE) in a central Peruvian Highland district by using 4 diagnostic methods: ultrasonography for 949 persons, radiography for 829, and 2 serologic tests for 929 (2 immunoblot formats using bovine hydatid cyst fluid [IBCF] and recombinant EpC1 glutathione S-transferase [rEpC1-GST] antigens). For the IBCF and rEpC1-GST testing, prevalence of liver and pulmonary CE was 4.7% and 1.1% and seropositivity was 8.9% and 19.7%, respectively. Frequency of seropositive results for IBCF and rEpC1-GST testing was 35.7% and 16.7% (all hepatic cysts), 47.1% and 29.4% (hepatic calcifications excluded), and 22.2% and 33.3% (lung cysts), respectively. Weak immune response against lung cysts, calcified cysts, small cysts, and cysts in sites other than lung and liver might explain the poor performance of the serodiagnostic tests. We confirm that CE is highly endemic to Peru and emphasize the limited performance of available serologic assays in the field. PMID:18258119

  20. Rickettsial Disease in the Peruvian Amazon Basin

    PubMed Central

    Kocher, Claudine; Morrison, Amy C.; Leguia, Mariana; Loyola, Steev; Castillo, Roger M.; Galvez, Hugo A.; Astete, Helvio; Flores-Mendoza, Carmen; Ampuero, Julia S.; Bausch, Daniel G.; Halsey, Eric S.; Cespedes, Manuel; Zevallos, Karine; Jiang, Ju; Richards, Allen L.

    2016-01-01

    Using a large, passive, clinic-based surveillance program in Iquitos, Peru, we characterized the prevalence of rickettsial infections among undifferentiated febrile cases and obtained evidence of pathogen transmission in potential domestic reservoir contacts and their ectoparasites. Blood specimens from humans and animals were assayed for spotted fever group rickettsiae (SFGR) and typhus group rickettsiae (TGR) by ELISA and/or PCR; ectoparasites were screened by PCR. Logistic regression was used to determine associations between patient history, demographic characteristics of participants and symptoms, clinical findings and outcome of rickettsial infection. Of the 2,054 enrolled participants, almost 2% showed evidence of seroconversion or a 4-fold rise in antibody titers specific for rickettsiae between acute and convalescent blood samples. Of 190 fleas (Ctenocephalides felis) and 60 ticks (Rhipicephalus sanguineus) tested, 185 (97.4%) and 3 (5%), respectively, were positive for Rickettsia spp. Candidatus Rickettsia asemboensis was identified in 100% and 33% of the fleas and ticks tested, respectively. Collectively, our serologic data indicates that human pathogenic SFGR are present in the Peruvian Amazon and pose a significant risk of infection to individuals exposed to wild, domestic and peri-domestic animals and their ectoparasites. PMID:27416029

  1. Rickettsial Disease in the Peruvian Amazon Basin.

    PubMed

    Kocher, Claudine; Morrison, Amy C; Leguia, Mariana; Loyola, Steev; Castillo, Roger M; Galvez, Hugo A; Astete, Helvio; Flores-Mendoza, Carmen; Ampuero, Julia S; Bausch, Daniel G; Halsey, Eric S; Cespedes, Manuel; Zevallos, Karine; Jiang, Ju; Richards, Allen L

    2016-07-01

    Using a large, passive, clinic-based surveillance program in Iquitos, Peru, we characterized the prevalence of rickettsial infections among undifferentiated febrile cases and obtained evidence of pathogen transmission in potential domestic reservoir contacts and their ectoparasites. Blood specimens from humans and animals were assayed for spotted fever group rickettsiae (SFGR) and typhus group rickettsiae (TGR) by ELISA and/or PCR; ectoparasites were screened by PCR. Logistic regression was used to determine associations between patient history, demographic characteristics of participants and symptoms, clinical findings and outcome of rickettsial infection. Of the 2,054 enrolled participants, almost 2% showed evidence of seroconversion or a 4-fold rise in antibody titers specific for rickettsiae between acute and convalescent blood samples. Of 190 fleas (Ctenocephalides felis) and 60 ticks (Rhipicephalus sanguineus) tested, 185 (97.4%) and 3 (5%), respectively, were positive for Rickettsia spp. Candidatus Rickettsia asemboensis was identified in 100% and 33% of the fleas and ticks tested, respectively. Collectively, our serologic data indicates that human pathogenic SFGR are present in the Peruvian Amazon and pose a significant risk of infection to individuals exposed to wild, domestic and peri-domestic animals and their ectoparasites.

  2. Pharmacogenomic assessment of Mexican and Peruvian populations

    PubMed Central

    Marsh, Sharon; King, Cristi R; Van Booven, Derek J; Revollo, Jane Y; Gilman, Robert H; McLeod, Howard L

    2015-01-01

    Background Clinically relevant polymorphisms often demonstrate population-specific allele frequencies. Central and South America remain largely uncategorized in the context of pharmacogenomics. Materials & methods We assessed 15 polymorphisms from 12 genes (ABCB1 3435C>T, ABCG2 Q141K, CYP1B1*3, CYP2C19*2, CYP3A4*1B, CYP3A5*3C, ERCC1 N118N, ERCC2 K751Q, GSTP1 I105V, TPMT 238G>C, TPMT 460G>A, TPMT 719A>G, TYMS TSER, UGT1A1*28 and UGT1A1 −3156G>A) in 81 Peruvian and 95 Mexican individuals. Results Six polymorphism frequencies differed significantly between the two populations: ABCB1 3435C>T, CYP1B1*3, GSTP1 I105V, TPMT 460G>A, UGT1A1*28 and UGT1A1 −3156G>A. The pattern of observed allele frequencies for all polymorphisms could not be accurately estimated from any single previously studied population. Conclusion This highlights the need to expand the scope of geographic data for use in pharmacogenomics studies. PMID:25916516

  3. Hydrological Predictability for the Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Towner, Jamie; Stephens, Elizabeth; Cloke, Hannah; Bazo, Juan; Coughlan, Erin; Zsoter, Ervin

    2017-04-01

    Population growth in the Peruvian Amazon has prompted the expansion of livelihoods further into the floodplain and thus increasing vulnerability to the annual rise and fall of the river. This growth has coincided with a period of increasing hydrological extremes with more frequent severe flood events. The anticipation and forecasting of these events is crucial for mitigating vulnerability. Forecast-based Financing (FbF) an initiative of the German Red Cross implements risk reducing actions based on threshold exceedance within hydrometeorological forecasts using the Global Flood Awareness System (GloFAS). However, the lead times required to complete certain actions can be long (e.g. several weeks to months ahead to purchase materials and reinforce houses) and are beyond the current capabilities of GloFAS. Therefore, further calibration of the model is required in addition to understanding the climatic drivers and associated hydrological response for specific flood events, such as those observed in 2009, 2012 and 2015. This review sets out to determine the current capabilities of the GloFAS model while exploring the limits of predictability for the Amazon basin. More specifically, how the temporal patterns of flow within the main coinciding tributaries correspond to the overall Amazonian flood wave under various climatic and meteorological influences. Linking the source areas of flow to predictability within the seasonal forecasting system will develop the ability to expand the limit of predictability of the flood wave. This presentation will focus on the Iquitos region of Peru, while providing an overview of the new techniques and current challenges faced within seasonal flood prediction.

  4. Serologic Evidence of Scrub Typhus in the Peruvian Amazon

    PubMed Central

    Jiang, Ju; Morrison, Amy C.; Castillo, Roger; Leguia, Mariana; Loyola, Steev; Ampuero, Julia S.; Cespedes, Manuel; Halsey, Eric S.; Bausch, Daniel G.; Richards, Allen L.

    2017-01-01

    Using a large, passive, febrile surveillance program in Iquitos, Peru, we retrospectively tested human blood specimens for scrub typhus group orientiae by ELISA, immunofluorescence assay, and PCR. Of 1,124 participants, 60 (5.3%) were seropositive, and 1 showed evidence of recent active infection. Our serologic data indicate that scrub typhus is present in the Peruvian Amazon. PMID:28726619

  5. An Information System for the Peruvian Air Force Hospital.

    DTIC Science & Technology

    1981-06-01

    INFORMATION SYSTEM IN THE PERUVIAN AIR FORCE HOSPITAL ------------------------------- 21 A. THE USE OF COMPUTER CENTER IN THE NEW SYSTEM...29 4. Pharmacy System -------------------------- 31 5. Financial System ------------------------ 32 VI. REACTION AGAINST A NEW SYSTEM...problems that all new Systems bring when implemented, especially with the use of a computer, and reactions of the medical personnel to the innovation of

  6. Prevalence and Factors Associated with Frailty Among Peruvian Older Adults

    PubMed Central

    Runzer-Colmenares, Fernando M.; Samper-Ternent, Rafael; Snih, Soham Al; Ottenbacher, Kenneth J.; Parodi, José F.; Wong, Rebeca

    2013-01-01

    The objective of this study is to examine the prevalence and factors associated with frailty in Peruvian Navy Veteran's older adults and family members. A total of 311 non-institutionalized men and women aged 60 years and older, from the Geriatrics Service of the Peruvian Navy Medical Center (Centro Médico Naval “Cirujano Mayor Santiago Távara”) were assessed between May and October 2010. Frailty was defined as having two or more of the following components: 1) unintentional weight-loss, 2) weakness (lowest 20% in grip-strength), 3) self-reported exhaustion, and 4) slow walking speed (lowest 20% 8-meter walk-time in seconds). Additionally, information on socio-demographic factors, medical conditions, depressive symptoms, disability, and cognitive function were obtained. Of the 311 participants, 78 (25.1%) were not frail, 147 (47.3%) were pre-frail, and 86 (27.8%) were frail. Using logistic regression analysis, we found that older age, being married, falls in the last year and disability were factors significantly associated with being frail. We conclude that prevalence of pre-frail and frail status in Peruvian Navy Veterans and family members is high. Our data reports risk factors for frailty that have been reported in the past in other population groups. A larger sample and longitudinal follow-up are needed to design and implement comprehensive geriatric interventions that can benefit Peruvian Navy Veteran's older adults at risk of becoming frail. PMID:23978328

  7. Moral Education and Post-War Societies: The Peruvian Case

    ERIC Educational Resources Information Center

    Frisancho, Susana; Reategui, Felix

    2009-01-01

    This article analyses the unique challenges and needs of moral and citizenship education in post-war Peruvian society. It assumes the explanation of the roots, the facts and the enduring negative consequences of violence as described in the final report of the Comision de la Verdad y Reconciliacion (CVR) [Truth and Reconciliation Commission]…

  8. Moral Education and Post-War Societies: The Peruvian Case

    ERIC Educational Resources Information Center

    Frisancho, Susana; Reategui, Felix

    2009-01-01

    This article analyses the unique challenges and needs of moral and citizenship education in post-war Peruvian society. It assumes the explanation of the roots, the facts and the enduring negative consequences of violence as described in the final report of the Comision de la Verdad y Reconciliacion (CVR) [Truth and Reconciliation Commission]…

  9. Layout as Political Expression: Visual Literacy and the Peruvian Press.

    ERIC Educational Resources Information Center

    Barnhurst, Kevin G.

    Newspaper layout and design studies ignore politics, and most studies of newspaper politics ignore visual design. News layout is generally thought to be a set of neutral, efficient practices. This study suggests that the political position of Peruvian newspapers parallels their visual presentation of terrorism. The liberal "La Republica"…

  10. Bioactive Compounds from Plants Used in Peruvian Traditional Medicine.

    PubMed

    Lock, Olga; Perez, Eleucy; Villar, Martha; Flores, Diana; Rojas, Rosario

    2016-03-01

    It is estimated that there are as many as 1400 plant species currently used in traditional Peruvian medicine; however, only a few have undergone scientific investigation. In this paper, we make a review of the botanical, chemical, pharmacological and clinical propierties of the most investigated Peruvian medicinal plants. The plant species selected for this review are: Smallanthus sonchifolius (yacon), Croton lechleri (sangre de grado), Uncaria tomentosa/U. guianensis (uña de gato), Lepidium meyenii (maca), Physalis peruviana (aguaymanto), Minthostachys mollis (muña), Notholaena nivea (cuti-cuti), Maytenus macrocarpa (chuchuhuasi), Dracontium loretense (jergon sacha), Gentianella nitida (hercampuri), Plukenetia volubilis (sacha inchi) and Zea mays (maiz morado). For each of these plants, information about their traditional uses and current commercialization is also included.

  11. Susceptibility of Peruvian Mosquitoes to Eastern Equine Encephalitis virus

    DTIC Science & Technology

    2008-07-01

    VECTOR/PATHOGEN/HOST INTERACTION, TRANSMISSION Susceptibility of Peruvian Mosquitoes to Eastern Equine Encephalitis Virus M. J. TURELL,1 M. L...the Amazon Basin, near Iquitos, Peru, and used in experimental studies to evaluate their susceptibility to strains of eastern equine encephalitis virus...enzootic vector of EEEV in this region. KEY WORDS Peru, eastern equine encephalitis virus, transmission, mosquito Eastern equine encephalitis virus (EEEV

  12. [Development of pneumoconiosis and outsourcing work in peruvian miners].

    PubMed

    Cáceres-Mejía, Brenda; Mayta-Tristán, Percy; Pereyra-Elías, Reneé; Collantes, Héctor; Cáceres-Leturia, Walter

    2015-10-01

    The aim of this study is to evaluate the association between the time of outsourced work and the development of pneumoconiosis in Peruvian miners who attended the "Centro Nacional de Salud Ocupacional y Protección al Ambiente para la Salud" between 2008 and 2011. Retrospective case-control study. Cases were defined as workers diagnosed of pneumoconiosis under standardized criteria. Outsourced work was defined as the time (in months) of work in a company that does not own the primary mining project. The project owner company was registered in the Mining Companies Directory (Ministerio de Energía y Minas). We used multiple logistic regression with crude and adjusted ORs. The study comprised 391 cases and 1519 controls. In both groups, most of the study subjects had a level of education lower than complete high school and were born and currently lived in the Peruvian highlands. There was statistically significant association between more frequency of pneumoconiosis and working 10 or more years in an outsourced company (OR: 1.50; 95%CI: 1.05-1.14; p=0.026). Miners with pneumoconiosis were more likely not to have education (OR: 3.07; 95%CI: 1.55-6.08; p=0.001), be currently living at the Peruvian highlands (OR: 1.40; 95%CI: 1.10-1.78; p=0.007) and to have more than 20 years of underground work history (OR: 8.92; 95%CI: 4.53-18.25; p<0.001). A statistically significant association was found between pneumoconiosis and the time of outsourced work. Not having education, residing in the Peruvian highlands and the time of underground work were associated risk factors.

  13. Retroviral Infections in Peruvian Men Who Have Sex With Men

    PubMed Central

    La Rosa, Alberto M.; Zunt, Joseph R.; Peinado, Jesus; Lama, Javier R.; Ton, Thanh G.N.; Suarez, Luis; Pun, Monica; Cabezas, Cesar; Sanchez, Jorge

    2009-01-01

    We tested 2,655 Peruvian MSM for retroviral infection: HTLV-1 was detected in 48 (1.8%), HTLV-2 in 28 (1.1%), and HTLV-1 and -2 in 5 (0.2%); HIV infection was detected in 329 (12.4 %); 24 (7.3%) were coinfected with HTLV. Risk factors for HTLV-1 and -2 varied with sexual role. PMID:19480577

  14. Clinical research training of Peruvian neurologists: a baseline assessment.

    PubMed

    Navarro-Chumbes, Gian Carlos; Montano-Torres, Silvia Margarita; Díaz-Vásquez, Alberto; Zunt, Joseph Raymond

    2010-06-21

    In Peru, despite a strong clinical research infrastructure in Lima, and Masters degree programs in epidemiology at three universities, few neurologists participate in clinical research. It was our objective to identify perceived needs and opportunities for increasing clinical research capacity and training opportunities for Peruvian neurologists. We conducted a descriptive, cross-sectional survey of Peruvian neurologists in Lima and Arequipa, Peru. Forty-eight neurologists completed written surveys and oral interviews. All neurologists reported interest in clinical research, but noted that lack of time and financial resources limited their ability to participate. Although most neurologists had received some training in epidemiology and research design as medical students or residents, the majority felt these topics were not adequately covered. Neurologists in Arequipa noted international funding for clinical research was uncommon outside the capital city of Lima. We concluded that clinical research is important to Peruvian neurologists. The three main barriers to increased participation in clinical research identified by neurologists were insufficient training in clinical research methodology, meager funding opportunities, and lack of dedicated time to participate in clinical research. Distance learning holds promise as a method for providing additional training in clinical research methodology, especially for neurologists who may have difficulty traveling to larger cities for additional training.

  15. Clinical research training of Peruvian neurologists: a baseline assessment

    PubMed Central

    Navarro-Chumbes, Gian Carlos; Montano-Torres, Silvia Margarita; Díaz-Vásquez, Alberto; Zunt, Joseph Raymond

    2010-01-01

    In Peru, despite a strong clinical research infrastructure in Lima, and Masters degree programs in epidemiology at three universities, few neurologists participate in clinical research. It was our objective to identify perceived needs and opportunities for increasing clinical research capacity and training opportunities for Peruvian neurologists. We conducted a descriptive, cross-sectional survey of Peruvian neurologists in Lima and Arequipa, Peru. Forty-eight neurologists completed written surveys and oral interviews. All neurologists reported interest in clinical research, but noted that lack of time and financial resources limited their ability to participate. Although most neurologists had received some training in epidemiology and research design as medical students or residents, the majority felt these topics were not adequately covered. Neurologists in Arequipa noted international funding for clinical research was uncommon outside the capital city of Lima. We concluded that clinical research is important to Peruvian neurologists. The three main barriers to increased participation in clinical research identified by neurologists were insufficient training in clinical research methodology, meager funding opportunities, and lack of dedicated time to participate in clinical research. Distance learning holds promise as a method for providing additional training in clinical research methodology, especially for neurologists who may have difficulty traveling to larger cities for additional training. PMID:21577342

  16. A preliminary study of a Peruvian diet using dietary analysis and hair mineral content as indicators.

    PubMed

    Tueller, Daniel J; Eggett, Dennis L; Parker, Tory L

    2013-11-01

    Observations among former American residents living long-term in Peru suggested that hair health improved while in Peru. To determine if a Peruvian diet correlates with hair composition, dietary intake of nutrients and mineral content of hair were measured among Peruvian and matched US residents. Selected foods from Peru were also analyzed for mineral and antioxidant content and compared with equivalent foods available in the USA. Statistically significant differences between Peruvian and US residents' hair were found for sodium (decreased in Peru, p = 0.007) and vanadium (decreased in Peru, p = 0.03). Differences in hair composition between residencies may be explained by lower dietary sodium and vanadium intake among Peruvian residents or by lower concentrations of these minerals in Peruvian drinking water. Many significant mineral differences were also identified between Peruvian foods and their US equivalents. Although no statistically significant correlations between dietary intake and hair mineral content were found, results indicate that a Peruvian diet contributes differently to hair composition than a US diet. More research is needed to elucidate the link between a Peruvian diet and specific aspects of hair health.

  17. Interculturality for Afro-Peruvians: Towards a Racially Inclusive Education in Peru

    ERIC Educational Resources Information Center

    Valdiviezo, Laura Alicia

    2006-01-01

    Intercultural education policy and programs in Peru emerged as a response to the right of education for marginalised indigenous populations. Under the influence of international dialogue regarding education for all, Peruvian policy has recently proposed interculturality as a guiding principle of education for all Peruvians. In this context,…

  18. Immune response to measles vaccine in Peruvian children.

    PubMed Central

    Bautista-López, N. L.; Vaisberg, A.; Kanashiro, R.; Hernández, H.; Ward, B. J.

    2001-01-01

    OBJECTIVE: To evaluate the immune response in Peruvian children following measles vaccination. METHODS: Fifty-five Peruvian children received Schwarz measles vaccine (about 10(3) plaque forming units) at about 9 months of age. Blood samples were taken before vaccination, then twice after vaccination: one sample at between 1 and 4 weeks after vaccination and the final sample 3 months post vaccination for evaluation of immune cell phenotype and lymphoproliferative responses to measles and non-measles antigens. Measles-specific antibodies were measured by plaque reduction neutralization. FINDINGS: The humoral response developed rapidly after vaccination; only 4 of the 55 children (7%) had plaque reduction neutralization titres <200 mlU/ml 3 months after vaccination. However, only 8 out of 35 children tested (23%) had lymphoproliferative responses to measles antigens 3-4 weeks after vaccination. Children with poor lymphoproliferative responses to measles antigens had readily detectable lymphoproliferative responses to other antigens. Flow cytometric analysis of peripheral blood mononuclear cells revealed diffuse immune system activation at the time of vaccination in most children. The capacity to mount a lymphoproliferative response to measles antigens was associated with expression of CD45RO on CD4+ T-cells. CONCLUSION: The 55 Peruvian children had excellent antibody responses after measles vaccination, but only 23% (8 out of 35) generated detectable lymphoproliferative responses to measles antigens (compared with 55-67% in children in the industrialized world). This difference may contribute to the less than uniform success of measles vaccination programmes in the developing world. PMID:11731811

  19. Seasonality in marine ecosystems: Peruvian seabirds, anchovy, and oceanographic conditions.

    PubMed

    Passuni, Giannina; Barbraud, Christophe; Chaigneau, Alexis; Demarcq, Hervé; Ledesma, Jesus; Bertrand, Arnaud; Castillo, Ramiro; Perea, Angel; Mori, Julio; Viblanc, Vincent A; Torres-MaitaA, Jose; Bertrand, Sophie

    2016-01-01

    In fluctuating environments, matching breeding timing to periods of high resource availability is crucial for the fitness of many vertebrate species, and may have major consequences on population health. Yet, our understanding of the proximate environmental cues driving seasonal breeding is limited. This is particularly the case in marine ecosystems, where key environmental factors and prey abundance and availability are seldom quantified. The Northern Humboldt Current System (NHCS) is a highly productive, low-latitude ecosystem of moderate seasonality. In this ecosystem, three tropical seabird species (the Guanay Cormorant Phalacrocorax bougainvillii, the Peruvian Booby Sula variegata, and the Peruvian Pelican Pelecanus thagus) live in sympatry and prey almost exclusively on anchovy, Engraulis ringens. From January 2003 to December 2012, we monitored 31 breeding sites along the Peruvian coast to investigate the breeding cycle of these species. We tested for relationships between breeding timing, oceanographic conditions, and prey availability using occupancy models. We found that all three seabird species exhibited seasonal breeding patterns, with marked interspecific differences. Whereas breeding mainly started during the austral winter/early spring and ended in summer/early fall, this pattern was stronger in boobies and pelicans than in cormorants. Breeding onset mainly occurred when upwelling was intense but ecosystem productivity was below its annual maxima, and when anchovy were less available and in poor physiological condition. Conversely, the abundance and availability of anchovy improved during chick rearing and peaked around the time of fledging. These results suggest that breeding timing is adjusted so that fledging may occur under optimal environmental conditions, rather than being constrained by nutritional requirements during egg laying. Adjusting breeding time so that fledglings meet optimal conditions at independence is unique compared with other

  20. Seasonality in marine ecosystems: Peruvian seabirds, anchovy, and oceanographic conditions.

    PubMed

    Passuni, Giannina; Barbraud, Christophe; Chaigneau, Alexis; Demarcq, Hervé; Ledesma, Jesus; Bertrand, Arnaud; Castillo, Ramiro; Perea, Angel; Mori, Julio; Viblanc, Vincent A; Torres-Maita, Jose; Bertrand, Sophie

    2016-01-01

    In fluctuating environments, matching breeding timing to periods of high resource availability is crucial for the fitness of many vertebrate species, and may have major consequences on population health. Yet, our understanding of the proximate environmental cues driving seasonal breeding is limited. This is particularly the case in marine ecosystems, where key environmental factors and prey abundance and availability are seldom quantified. The Northern Humboldt Current System (NHCS) is a highly productive, low-latitude ecosystem of moderate seasonality. In this ecosystem, three tropical seabird species (the Guanay Cormorant Phalacrocorax bougainvillii, the Peruvian Booby Sula variegata, and the Peruvian Pelican Pelecanus thagus) live in sympatry and prey almost exclusively on anchovy, Engraulis ringens. From January 2003 to December 2012, we monitored 31 breeding sites along the Peruvian coast to investigate the breeding cycle of these species. We tested for relationships between breeding timing, oceanographic conditions, and prey availability using occupancy models. We found that all three seabird species exhibited seasonal breeding patterns, with marked interspecific differences. Whereas breeding mainly started during the austral winter/early spring and ended in summer/early fall, this pattern was stronger in boobies and pelicans than in cormorants. Breeding onset mainly occurred when upwelling was intense but ecosystem productivity was below its annual maxima, and when anchovy were less available and in poor physiological condition. Conversely, the abundance and availability of anchovy improved during chick rearing and peaked around the time of fledging. These results suggest that breeding timing is adjusted so that fledging may occur under optimal environmental conditions, rather than being constrained by nutritional requirements during egg laying. Adjusting breeding time so that fledglings meet optimal conditions at independence is unique compared with other

  1. Gallstone disease in Peruvian coastal natives and highland migrants

    PubMed Central

    Moro, P; Checkley, W; Gilman, R; Cabrera, L; Lescano, A; Bonilla, J; Silva, B

    2000-01-01

    BACKGROUND—In a previous study, we found that gallstones were a common occurrence in the high altitude villages of the Peruvian Andes.
AIMS—To determine if high altitude (⩾ 1500 m) is a contributing risk factor for gallstone disease.
METHODS—We conducted a cross sectional study in a periurban community in Lima, Peru, and compared the prevalence of gallstone disease between coastal natives, highland (Sierra) natives and Sierra natives who had migrated to the coast. We also compared the prevalence rates from this study with those from a previous study conducted at high altitude. We examined 1534 subjects >15 years of age for gallstone disease. Subjects were interviewed for the presence or absence of risk factors.
RESULTS—Gallstone disease was more common in females (16.1 cases per 100, 95% CI 13.8-18.2) than in males (10.7 per 100, 95% CI 8.0-13.4). Females had a greater risk of gallstone disease, especially if they had used oral contraception and/or had four or more children. The age adjusted prevalence was not significantly different between coastal natives, Sierra migrants, and Andean villagers. The prevalence of gallstone disease was not associated with time since migration or with having native Sierra parents. After adjusting for other risk factors, Sierra natives who migrated to the coast had a lower prevalence of gallstone disease than coastal natives (odds ratio 0.74, 95% CI 0.58-0.94).
CONCLUSIONS—This study indicates that high altitude is not a positive risk factor for gallstone disease and confirms that this disease is common in Peruvians, which may be attributable to Peruvian-Indian ethnicity.


Keywords: gallstone disease; cholelithiasis; high altitude; risk factors; epidemiology; Peru PMID:10716689

  2. The Peruvian Continental Margin: Results from wide angle seismic Data

    NASA Astrophysics Data System (ADS)

    Krabbenhoeft, A.; Bialas, J.; Kopp, H.; Kukowski, N.; Huebscher, C.

    2003-04-01

    Within the scope of the GEOPECO (Geophysical Experiments at the Peruvian Continental Margin) project, seismic investigations along the Pacific margin of Peru were carried out using ocean bottom hydrophones (OBH) and seismometers (OBS) recording marine airgun shots. The structure and the P- wave velocity of the oblique subducting Nazca and overriding South-American Plates from 8°S to 15°S were determined by forward modeling and tomographic inversion of the wide-angle seismic data combined with the analysis of reflection seismic data. The region south of 12°S has been influenced by the southward migration of the aseismic Nazca Ridge the past 11 Ma. The oceanic Nazca Plate is divided by Mendana Fracture Zone (MFZ) which marks a transition zone of a different crustal age of approximately 28 Ma in the north to 38 Ma in the south at the Peruvian trench. North of MFZ the oceanic crust is influenced by Trujillo Trough trending N15E and the surrounding extensional stresses leading to a crustal thinning as can be seen in the northernmost refraction seismic model. The oceanic crust south of MFZ is overall homogeneous with a thin pelagic sedimentary layer and normal oceanic crustal layers. The P-wave velocity of the mantle is overall 7.9-8.1km/s. The Peruvian Continental Margin is characterized by the continental slope and several basins, Trujillo and Yaquina basin, Lima basin and Pisco basin, which are partly affected by the southward migration of the subducting Nazca Ridge. This caused uplift and subsidence along the margin leading to erosional tectonic features. The basins and continental basement could be mapped with forward modeling and tomographic inversion as well as the continental backstop on each profile. An accretionary prism is set up with a width of 20 to 30 km and 4 to 5 km thickness which does not further increase in size as revealed by the profiles recorded further north of Nazca Ridge. This and a taper of 14- 17 degrees at the collision zone indicates that

  3. Isolation of cytotoxic metabolites from targeted peruvian amazonian medicinal plants.

    PubMed

    Aponte, José C; Vaisberg, Abraham J; Rojas, Rosario; Caviedes, Luz; Lewis, Walter H; Lamas, Gerardo; Sarasara, César; Gilman, Robert H; Hammond, Gerald B

    2008-01-01

    The antiproliferative bioassay-guided fractionation of five Peruvian plants, Doliocarpus dentatus, Picramnia sellowii, Strychnos mitscherlichii, Iryanthera juruensis, and Croton alnifolius, led to the isolation and identification of their different major cytotoxic constituents, betulinic acid (1), nataloe-emodin (2), bisnordihydrotoxyferine (4), 2',4'-dihydroxy-6'-methoxy-3,4-methylenedioxydihydrochalcone (5), and 2',4'-dihydroxy-4,6'-dimethoxydihydrochalcone (6) and 12-O-tetradecanoylphorbol-13-acetate (7), respectively. Eight human tumor cell lines and two nontumorigenic cell lines were used in this investigation. Their in vitro activity against Mycobacterium tuberculosis is also reported.

  4. First documented outbreak of dengue in the Peruvian Amazon region.

    PubMed

    Phillips, I; Need, J; Escamilla, J; Colán, E; Sánchez, S; Rodríguez, M; Vásquez, L; Seminario, J; Betz, T; da Rosa, A T

    1992-01-01

    This article describes a classical dengue outbreak caused by dengue serotypes 1 and 4 that occurred from March to July 1990 in the city of Iquitos and surrounding areas of Loreto Department in the Peruvian Amazon. Epidemiologic data indicate that more than 150,000 persons may have been affected in Iquitos alone. Another dengue outbreak occurred in Tarapoto, a city in the neighboring department of San Martín. Laboratory data indicate that the same dengue serotypes were involved in both outbreaks. No cases of dengue hemorrhagic fever/shock syndrome appear to have occurred. Prior to this outbreak, no indigenous dengue cases had been documented in Peru.

  5. Mitochondrial genome of the Peruvian scallop Argopecten purpuratus (Bivalvia: Pectinidae).

    PubMed

    Marín, Alan; Alfaro, Rubén; Fujimoto, Takafumi; Arai, Katsutoshi

    2015-01-01

    The mitochondrial genome of the Peruvian scallop Argopecten purpuratus was determined. The length of the mitochondrial coding region is 15,608 bp. A typical bivalve mitochondrial composition was detected with 12 protein-coding genes, 2 ribosomal RNA genes and 21 transfer RNA genes, with the absence of the atp8 gene. Fifty percent of the protein-coding genes use typical ATG start codon, whereas five genes utilize ATA as their start codon. Only one gene was found to utilize TTG as its start codon. The A. purpuratus mitogenome shows a significant similarity to that of A. irradians irradians, in length as well as in gene composition.

  6. Retroviral infection in Peruvian men who have sex with men.

    PubMed

    La Rosa, Alberto M; Zunt, Joseph R; Peinado, Jesus; Lama, Javier R; Ton, Thanh G N; Suarez, Luis; Pun, Monica; Cabezas, Cesar; Sanchez, Jorge

    2009-07-01

    We tested 2655 Peruvian men who have sex with men for the presence of retroviral infection. Human T cell lymphotropic virus type 1 (HTLV-1) was detected in 48 (1.8%) of the patients, HTLV-2 was detected in 28 (1.1%), and HTLV-1 and HTLV-2 were both detected in 5 (0.2%). Human immunodeficiency virus infection was detected in 329 (12.4%) of the patients; 24 (7.3%) had HTLV coinfection. Risk factors for HTLV-1 and HTLV-2 infection varied with sexual role.

  7. Outbreak of gastroenteritis at a Peruvian naval base.

    PubMed

    Jones, Franca R; Ortiz, Mario; Soriano, Imelda; Utz, Gregory; Saldarriaga, Emilia; Cumpa, Raquel; Collantes, Violeta; Leandro, Yuliana; Bernal, Manuela Maria; Ucanan, Luis Enrique; Colina, Olga; Lescano, Andres; Batsel, Tanis

    2006-11-01

    In April of 2003, an outbreak of gastroenteritis was reported in a training command (Centro de Instrucción Técnica y Entrenamiento Naval (CITEN)) at a Peruvian naval base located near Lima, Peru. The Naval Medical Research Center Detachment, in collaboration with the National Peruvian Naval Hospital, conducted an investigation to determine the causative agent and potential source of the outbreak. Between April 3 and 5, 172 (16%) of 1,092 military trainees reported to the CITEN clinic with diarrhea. Of 74 trainees for whom bacterial cultures were performed, Shigella spp. were isolated from 5 (6.8%), Campylobacter spp. from 5 (6.8%), and enterotoxigenic Escherichia coli from 2 (2.7%). Pathogenic parasites were identified in 22 of 64 (34%) trainees for whom microscopic observation for ova and parasites was performed. Stool samples from asymptomatic controls could not be collected, thus we were unable to confirm that the enteropathogens isolated were the etiologic agent(s). Several food items and the hands of food handlers were contaminated with coliform bacteria and drinking water was not adequately chlorinated. Preventative measures have since reduced the number of diarrhea cases at the CITEN.

  8. Organic carbon production, mineralisation and preservation on the Peruvian margin

    NASA Astrophysics Data System (ADS)

    Dale, A. W.; Sommer, S.; Lomnitz, U.; Montes, I.; Treude, T.; Liebetrau, V.; Gier, J.; Hensen, C.; Dengler, M.; Stolpovsky, K.; Bryant, L. D.; Wallmann, K.

    2015-03-01

    Carbon cycling in Peruvian margin sediments (11 and 12° S) was examined at 16 stations, from 74 m water depth on the middle shelf down to 1024 m, using a combination of in situ flux measurements, sedimentary geochemistry and modelling. Bottom water oxygen was below detection limit down to ca. 400 m and increased to 53 μM at the deepest station. Sediment accumulation rates decreased sharply seaward of the middle shelf and subsequently increased at the deep stations. The organic carbon burial efficiency (CBE) was unusually low on the middle shelf (<20%) when compared to an existing global database, for reasons which may be linked to episodic ventilation of the bottom waters by oceanographic anomalies. Deposition of reworked, degraded material originating from sites higher up on the slope is proposed to explain unusually high sedimentation rates and CBE (>60%) at the deep oxygenated sites. In line with other studies, CBE was elevated under oxygen-deficient waters in the mid-water oxygen minimum zone. Organic carbon rain rates calculated from the benthic fluxes alluded to efficient mineralisation of organic matter in the water column compared to other oxygen-deficient environments. The observations at the Peruvian margin suggest that a lack of oxygen does not greatly affect the degradation of organic matter in the water column but promotes the preservation of organic matter in sediments.

  9. [Visibility and productivity of the biomedical Peruvian journals].

    PubMed

    Huamaní, Charles; Pacheco-Romero, José

    2009-01-01

    Biomedical journals have suffered world wide revolutions due to globalization of information, evolving from the printed version to the electronic one. The status of Peruvian medical journals is not currently known. To determine indexing, production for 2005 to 2007; and visibility of Peruvian biomedical journals for 2008. We identified indexed journals in Medline, SciELO-Peru, Redalyc, LILACS, and others, through informatic search and described the journals production with more indizations, estimating the original research production index. An analysis of electronic visibility of the journals most indexed in SciELO-Peru, Redalyc and SISBIB data bases is done. We identified 29 current journals by 2007. Only Revista de Gastroenterologia del Peru was indexed to Medline. Revista Peruana de Medicina Experimental y Salud Publica was the journal with more production, with 176 publications between 2005 and 2007.Anales de la Facultad de Medicina was the journal with the higher original investigation index, with 0,61. Anales de la Facultad de Medicina had the higher number of electronic visits with 963 965 visits in 2008. There is a great diversity of biomedical journals in Peru but few are indexed and only one is seen in Medline. Original research production is not high but journals electronic visibility is above 600 thousand visitors.

  10. Language, Culture, and Power: Intercultural Bilingual Education among the Urarina of Peruvian Amazonia.

    ERIC Educational Resources Information Center

    Dean, Bartholomew

    1999-01-01

    The Peruvian national indigenous federation established a bilingual, intercultural teachers' training program to counter stereotypes of indigenous people portrayed in the authoritarian, monolingual Spanish national curriculum, and to enhance language preservation, ethnic mobilization, and cultural survival. A complementary transitional bilingual…

  11. Language, Culture, and Power: Intercultural Bilingual Education among the Urarina of Peruvian Amazonia.

    ERIC Educational Resources Information Center

    Dean, Bartholomew

    1999-01-01

    The Peruvian national indigenous federation established a bilingual, intercultural teachers' training program to counter stereotypes of indigenous people portrayed in the authoritarian, monolingual Spanish national curriculum, and to enhance language preservation, ethnic mobilization, and cultural survival. A complementary transitional bilingual…

  12. Compositional characterization of native Peruvian chili peppers (Capsicum spp.).

    PubMed

    Meckelmann, Sven W; Riegel, Dieter W; van Zonneveld, Maarten J; Ríos, Llermé; Peña, Karla; Ugas, Roberto; Quinonez, Lourdes; Mueller-Seitz, Erika; Petz, Michael

    2013-03-13

    The national Capsicum germplasm bank of Peru at INIA holds a unique collection of more than 700 Capsicum accessions, including many landraces. These conserved accessions have never been thoroughly characterized or evaluated. Another smaller collection exists at UNALM, and CIDRA provided taxonomically characterized fruits from the Amazon region of Ucayali. Of these collections, 147 accessions have been selected to represent the biodiversity of Peruvian Capsicum annuum , Capsicum baccatum , Capsicum chinense , and Capsicum frutescens by morphological traits as well as by agronomic characteristics and regional origin. All fruits from the selected accessions have been oven-dried and ground in Peru and analyzed in Germany. Results are reported for each accession by total capsaicinoids and capsaicinoid pattern, total polyphenol content, antioxidant capacity, specific flavonoids (quercetin, kaempferol, luteolin, apigenin), fat content, vitamin C, surface color, and extractable color. A wide variability in phytochemical composition and concentration levels was found.

  13. [Ethics and medicine: the experience of the Peruvian Medical Association].

    PubMed

    Mendoza F, Alfonso

    2011-12-01

    This article shows the work of the Peruvian Medical Association with respect to ethical disciplinary procedures, but also shows how, beyond the ethical control, the Order has promoted through a set of actions, a technically competent health care that respects the dignity and fundamental human rights. Part of these actions are the establishment of the Patient's Day, the emphasis in improving the quality and safety in the care of the users of the health services, the initiative to prevent and treat adverse events, the regulation and improvement of the physicians training both in pre as in post-graduate levels, and the demand for the establishment of an optimal health system and policies that will realize the right to health in the context of the principles of bioethics.

  14. Logging Concessions Enable Illegal Logging Crisis in the Peruvian Amazon

    PubMed Central

    Finer, Matt; Jenkins, Clinton N.; Sky, Melissa A. Blue; Pine, Justin

    2014-01-01

    The Peruvian Amazon is an important arena in global efforts to promote sustainable logging in the tropics. Despite recent efforts to achieve sustainability, such as provisions in the US–Peru Trade Promotion Agreement, illegal logging continues to plague the region. We present evidence that Peru's legal logging concession system is enabling the widespread illegal logging via the regulatory documents designed to ensure sustainable logging. Analyzing official government data, we found that 68.3% of all concessions supervised by authorities were suspected of major violations. Of the 609 total concessions, nearly 30% have been cancelled for violations and we expect this percentage to increase as investigations continue. Moreover, the nature of the violations indicate that the permits associated with legal concessions are used to harvest trees in unauthorized areas, thus threatening all forested areas. Many of the violations pertain to the illegal extraction of CITES-listed timber species outside authorized areas. These findings highlight the need for additional reforms. PMID:24743552

  15. [Blood lead in the inhabitants of 4 Peruvian localities].

    PubMed

    Ramírez, A V; Paucar, J C; Medina, J M

    1997-05-01

    During 1994 and 1995, a cross-sectional study was carried out to investigate the concentrations of lead in the blood of inhabitants of four Peruvian cities (Lima, Huancayo, La Oroya, and Yaupi) with different population densities and degrees of industrial development. In a random sample of 180 men and 180 women without occupational exposure to lead, blood lead levels were measured by the atomic absorption method with a Perkin Elmer 603 spectrophotometer without a graphite oven. The results revealed blood lead concentrations of 269 +/- 63 micrograms per liter (micrograms/L) in Lima, 224 +/- 47 micrograms/L in Huancayo; 348 +/- 40 micrograms/L in La Oroya, and 140 +/- 27 micrograms/L in Yaupi. It was concluded that blood lead levels in the inhabitants of these cities were related to the degree of industrialization and the population density of each locality.

  16. [Cat's Claw: an herb from the Peruvian Amazon].

    PubMed

    Steinberg, P N

    1995-01-01

    Uncaria tomentosa, also known as cat's claw, an herb from the highlands of the Peruvian Amazon, has been used by natives for hundreds of years to treat immunologic and digestive disorders. Research began in the 1970s to discover the benefits of this plant in relieving symptoms of cancers, arthritis, and other ailments. It has the ability to cleanse the digestive tract, aiding victims of Crohn's, colitis, gastritis and more. In a 1989 study by Klaus Keplinger, several alkaloid oxidants found in the plant's roots showed an ability to stimulate the immune system. The principal alkaloids are isopteropodine and rynchophyiline. Extracts of cat's claw mixed with AZT in an experimental drug, called Krallendom, were effective in reducing symptoms in AIDS patients in Austria. The plant has been useful in reducing secondary effects of radiation and chemotherapy in cancer victims as well.

  17. Logging Concessions Enable Illegal Logging Crisis in the Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Finer, Matt; Jenkins, Clinton N.; Sky, Melissa A. Blue; Pine, Justin

    2014-04-01

    The Peruvian Amazon is an important arena in global efforts to promote sustainable logging in the tropics. Despite recent efforts to achieve sustainability, such as provisions in the US-Peru Trade Promotion Agreement, illegal logging continues to plague the region. We present evidence that Peru's legal logging concession system is enabling the widespread illegal logging via the regulatory documents designed to ensure sustainable logging. Analyzing official government data, we found that 68.3% of all concessions supervised by authorities were suspected of major violations. Of the 609 total concessions, nearly 30% have been cancelled for violations and we expect this percentage to increase as investigations continue. Moreover, the nature of the violations indicate that the permits associated with legal concessions are used to harvest trees in unauthorized areas, thus threatening all forested areas. Many of the violations pertain to the illegal extraction of CITES-listed timber species outside authorized areas. These findings highlight the need for additional reforms.

  18. The Peruvian diaspora: portrait of a migratory process.

    PubMed

    Durand, Jorge

    2010-01-01

    Since the 1980s and especially the 1990s, Peru has become a nation of emigrants. Emigration has become massive over the past two decades, and the Peruvian populations of the United States, Japan, and Spain have tripled in less than a decade. A survey of households in five localities, three urban and two rural, in and around Lima helps to reveal the special character of this emigration. It tends to involve older and better-educated individuals than are typical of international migration and to target a wider variety of destinations. Moreover, it is a multiclass phenomenon. The economic, political, and social crisis brought about by a change in the economic model, two decades of terrorism, and a succession of failed democratic administrations has affected the society as a whole, and international migration seems to operate as an escape valve.

  19. Benthic phosphorus cycling in the Peruvian oxygen minimum zone

    NASA Astrophysics Data System (ADS)

    Lomnitz, U.; Sommer, S.; Dale, A. W.; Löscher, C. R.; Noffke, A.; Wallmann, K.; Hensen, C.

    2015-10-01

    Oxygen minimum zones (OMZs) that impinge on continental margins favor the release of phosphorus (P) from the sediments to the water column, enhancing primary productivity and the maintenance or expansion of low-oxygen waters. A comprehensive field program in the Peruvian OMZ was undertaken to identify the sources of benthic P, including the analysis of particles from the water column, surface sediments and pore fluids as well as in situ benthic flux measurements. A major fraction of solid phase P was bound as particulate inorganic P (PIP) both in the water column and in sediments. Sedimentary PIP increased with depth in the sediment at the expense of particulate organic P (POP). The ratio of particulate organic carbon (POC) to POP exceeded the Redfield Ratio both in the water column (202 ± 29) and in surface sediments (303 ± 77). However, the POC to total particulate P (TPP = POP + PIP) ratio was close to Redfield in the water column (103 ± 9) and in sediment samples (102 ± 15) taken from the core of the OMZ. This observation suggests that the burial efficiencies of POC and TPP are similar under the low oxygen conditions prevailing in the Peruvian OMZ. Benthic fluxes of dissolved P were extremely high (up to 1.04 ± 0.31 mmol m-2 d-1) and exceeded the fluxes resulting from the degradation of particulate organic matter raining to the seabed. Most of the excess P may have been released by bacterial mats that had stored P during previous periods when bottom waters were less reducing. At one station located at the lower rim of the OMZ, dissolved P was taken up by the sediments indicating recent phosphorite formation.

  20. Organic carbon production, mineralization and preservation on the Peruvian margin

    NASA Astrophysics Data System (ADS)

    Dale, A. W.; Sommer, S.; Lomnitz, U.; Montes, I.; Treude, T.; Gier, J.; Hensen, C.; Dengler, M.; Stolpovsky, K.; Bryant, L. D.; Wallmann, K.

    2014-09-01

    Carbon cycling in Peruvian margin sediments (11° S and 12° S) was examined at 16 stations from 74 m on the inner shelf down to 1024 m water depth by means of in situ flux measurements, sedimentary geochemistry and modeling. Bottom water oxygen was below detection limit down to ca. 400 m and increased to 53 μM at the deepest station. Sediment accumulation rates and benthic dissolved inorganic carbon fluxes decreased rapidly with water depth. Particulate organic carbon (POC) content was lowest on the inner shelf and at the deep oxygenated stations (< 5%) and highest between 200 and 400 m in the oxygen minimum zone (OMZ, 15-20%). The organic carbon burial efficiency (CBE) was unexpectedly low on the inner shelf (< 20%) when compared to a global database, for reasons which may be linked to the frequent ventilation of the shelf by oceanographic anomalies. CBE at the deeper oxygenated sites was much higher than expected (max. 81%). Elsewhere, CBEs were mostly above the range expected for sediments underlying normal oxic bottom waters, with an average of 51 and 58% for the 11° S and 12° S transects, respectively. Organic carbon rain rates calculated from the benthic fluxes alluded to a very efficient mineralization of organic matter in the water column, with a Martin curve exponent typical of normal oxic waters (0.88 ± 0.09). Yet, mean POC burial rates were 2-5 times higher than the global average for continental margins. The observations at the Peruvian margin suggest that a lack of oxygen does not affect the degradation of organic matter in the water column but promotes the preservation of organic matter in marine sediments.

  1. Developmental Effects Determine Submaximal Arterial Oxygen Saturation in Peruvian Quechua

    PubMed Central

    León-Velarde, Fabiola; Rivera-Chira, María; Elías, Gianpietro; Brutsaert, Tom D.

    2015-01-01

    Abstract Kiyamu, Melisa, Fabiola León-Velarde, María Rivera-Chira, Gianpietro Elías, and Tom D. Brutsaert. Developmental effects determine submaximal arterial oxygen saturation in Peruvian Quechua. High Alt Med Biol 16, 138–146, 2015.—Andean high altitude natives show higher arterial oxygen saturation (Sao2) during exercise in hypoxia, compared to acclimatized sojourners. In order to evaluate the effects of life-long exposure to high altitude on Sao2, we studied two groups of well-matched, self-identified Peruvian Quechua natives who differed in their developmental exposure to hypoxia before and after a 2-month training period. Male and female volunteers (18–35 years) were recruited in Lima, Peru (150 m). The two groups were: a) Individuals who were born and raised at sea-level (BSL, n=34) and b) Individuals who were born and raised at high altitude (BHA, n=32), but who migrated to sea-level as adults (>16 years old). Exercise testing was conducted using a submaximal exercise protocol in normobaric hypoxia in Lima (BP=750 mmHg, Fio2=0.12), in order to measure Sao2 (%), ventilation (VE L/min) and oxygen consumption (Vo2, L/min). Repeated-measures ANOVA, controlling for VE/VO2 (L/min) and sex during the submaximal protocol showed that BHA maintained higher Sao2 (%) compared to BSL at all workloads before (p=0.005) and after training (p=0.017). As expected, both groups showed a decrease in Sao2 (%) (p<0.001), as workload increased. Resting Sao2 levels were not found to be different between groups. The results suggest that developmental exposure to altitude contributes to the maintenance of higher Sao2 levels during submaximal exercise at hypoxia. PMID:25977978

  2. Childhood abuse and adult-onset asthma among Peruvian women.

    PubMed

    Banerjee, Dipti; Gelaye, Bizu; Zhong, Qiu-Yue; Sanchez, Sixto E; Williams, Michelle A

    2017-06-26

    Childhood abuse has been found to be associated with adult-onset asthma; however, this association has not been studied in low- and middle-income countries with a high burden of gender-based violence, including childhood abuse. We examined the odds of asthma diagnosed at age 18 or older in relation to history of physical and sexual abuse among Peruvian pregnant women. This cross-sectional study collected demographic characteristics, history of abuse and asthma diagnoses from 3081 pregnant women. Logistic regression procedures estimated adjusted odds ratios and 95% confidence intervals (aOR, [95% CI]) for asthma diagnoses in relation to abuse. Overall, 71% of the women reported a history of abuse (<18 years), and asthma was diagnosed among 2.6% of the cohort participants. The prevalence of physical only, sexual only and both physical and sexual childhood abuse was 38, 8 and 25%, respectively. The history of physical only (1.16, [0.63-2.17]), sexual only (2.11, [0.92-4.84]) or both physical and sexual childhood abuse (1.75, [0.94-3.29]) was positively associated with increased odds of asthma, although the associations were not statistically significant in the multivariate analysis. However, the odds of asthma increased with increasing numbers of abuse events (ptrend = 0.01). Women who reported ≥3 abuse events had an increased odds of asthma (1.88, [1.06-3.34]). Our results do not provide convincing evidence that childhood abuse is associated with asthma among pregnant Peruvian women; however, we were able to demonstrate that an increased number of abuse events are associated with asthma. Further research is required to better understand the effects of abuse on asthma.

  3. Education and the community in the Peruvian educational reform

    NASA Astrophysics Data System (ADS)

    Malpica, Carlos

    1980-09-01

    The reform of Peruvian education initiated in 1972 was based on new concepts, postulated new policies and proposed to convert the old school system into a new educational system in accordance with the revolutionary process begun in 1968. The principles of permanent education, education in the community and the educating community inspired an ambitious educational model on a national scale, to organise community education nuclei (NECs) of a local dimension, in which a dynamic social education of a participatory and self-managerial character could be created. This process of nuclearisation, which has historical antecedents going back to the social, economic and political organisation of the Incan Empire, and was revived in the twentieth century by the creation of the famous Warisata School in Bolivia, has now undergone nine years of valuable experience in Peru, attempting to develop an efficient alternative to the old school model which originated before the Christian era. The community/education dialectic has suffered a profound change in Peru in the last ten years and the experience, whether of obstacles and limitations, appears to be valuable and irreversible. The non-statist, non-bureaucratic, non-party and non-private solution that was pursued by the Peruvian Revolution in the field of education is very attractive and could interest other countries of the region which, during the last 30 years have applied the nuclearisation model, as well as other countries in Latin America or other regions who have recently either initiated or considered it. This article presents the experience, relates it to its historical antecedents, gives some information on evaluation studies in progress and traces some perspectives or projections for educational nuclearisation.

  4. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes.

    PubMed

    Meissner, Henry O; Mscisz, Alina; Mrozikiewicz, Mieczyslaw; Baraniak, Marek; Mielcarek, Sebastian; Kedzia, Bogdan; Piatkowska, Ewa; Jólkowska, Justyna; Pisulewski, Pawel

    2015-09-01

    Glucosinolates were previously reported as physiologically-important constituents present in Peruvian Maca (Lepidium peruvianum Chacon) and linked to various therapeutic functions of differently-colored Peruvian Maca hypocotyls. In two separate Trials, three colours of Maca hypocotyls "Black", "Red" and "Yellow" (termed "Maca phenotypes"), were selected from mixed crops of Peruvian Maca for laboratory studies as fresh and after being dried. Individual Maca phenotypes were cultivated in the highlands of the Peruvian Andes at 4,200m a.s.l. (Junin and Ninacaca). Glucosinolate levels, chromatographic HPLC profiles and DNA variability in the investigated Maca phenotypes are presented. Genotypic profiles were determined by the ISSR-PCR and RAPD techniques. Compared to the Black and Red phenotypes, the Yellow phenotype contained much lower Glucosinolate levels measured against Glucotropaeolin and m-methoxy-glucotropaeolin standards, and exhibited different RAPD and ISSR-PCR reactions. The Red Maca phenotype showed the highest concentrations of Glucosinolates as compared to the Black and Yellow Maca. It appears that the traditional system used by natives of the Peruvian Andean highlands in preparing Maca as a vegetable dish (boiling dried Maca after soaking in water), to supplement their daily meals, is as effective as laboratory methods - for extracting Glucosinolates, which are considered to be one of the key bioactive constituents responsible for therapeutic functions of Peruvian Maca phenotypes. It is reasonable to assume that the HPLC and DNA techniques combined, or separately, may assist in determining ID and "Fingerprints" identifying individual Peruvian Maca phenotypes, hence confirming the authenticity of marketable Maca products. The above assumptions warrant further laboratory testing.

  5. Peruvian Maca (Lepidium peruvianum): (I) Phytochemical and Genetic Differences in Three Maca Phenotypes

    PubMed Central

    Meissner, Henry O.; Mscisz, Alina; Mrozikiewicz, Mieczyslaw; Baraniak, Marek; Mielcarek, Sebastian; Kedzia, Bogdan; Piatkowska, Ewa; Jólkowska, Justyna; Pisulewski, Pawel

    2015-01-01

    Glucosinolates were previously reported as physiologically-important constituents present in Peruvian Maca (Lepidium peruvianum Chacon) and linked to various therapeutic functions of differently-colored Peruvian Maca hypocotyls. In two separate Trials, three colours of Maca hypocotyls “Black”, “Red” and “Yellow” (termed “Maca phenotypes”), were selected from mixed crops of Peruvian Maca for laboratory studies as fresh and after being dried. Individual Maca phenotypes were cultivated in the highlands of the Peruvian Andes at 4,200m a.s.l. (Junin and Ninacaca). Glucosinolate levels, chromatographic HPLC profiles and DNA variability in the investigated Maca phenotypes are presented. Genotypic profiles were determined by the ISSR-PCR and RAPD techniques. Compared to the Black and Red phenotypes, the Yellow phenotype contained much lower Glucosinolate levels measured against Glucotropaeolin and m-methoxy-glucotropaeolin standards, and exhibited different RAPD and ISSR-PCR reactions. The Red Maca phenotype showed the highest concentrations of Glucosinolates as compared to the Black and Yellow Maca. It appears that the traditional system used by natives of the Peruvian Andean highlands in preparing Maca as a vegetable dish (boiling dried Maca after soaking in water), to supplement their daily meals, is as effective as laboratory methods - for extracting Glucosinolates, which are considered to be one of the key bioactive constituents responsible for therapeutic functions of Peruvian Maca phenotypes. It is reasonable to assume that the HPLC and DNA techniques combined, or separately, may assist in determining ID and “Fingerprints” identifying individual Peruvian Maca phenotypes, hence confirming the authenticity of marketable Maca products. The above assumptions warrant further laboratory testing. PMID:26508907

  6. A second hydrocarbon boom threatens the Peruvian Amazon: trends, projections, and policy implications

    NASA Astrophysics Data System (ADS)

    Finer, Matt; Orta-Martínez, Martí

    2010-01-01

    The Peruvian Amazon is home to extraordinary biological and cultural diversity, and vast swaths of this mega-diverse region remain largely intact. Recent analysis indicates, however, that the rapid proliferation of oil and gas exploration zones now threatens the region's biodiversity, indigenous peoples, and wilderness areas. To better elucidate this dynamic situation, we analyzed official Peruvian government hydrocarbon information and generated a quantitative analysis of the past, present, and future of oil and gas activities in the Peruvian Amazon. We document an extensive hydrocarbon history for the region—over 104 000 km of seismic lines and 679 exploratory and production wells—highlighted by a major exploration boom in the early 1970s. We show that an unprecedented 48.6% of the Peruvian Amazon has been recently covered by oil and gas concessions, up from just 7.1% in 2003. These oil and gas concessions overlap 17.1% of the Peruvian Amazon protected area system and over half of all titled indigenous lands. Moreover, we found that up to 72% of the Peruvian Amazon has been zoned for hydrocarbon activities (concessions plus technical evaluation agreements and proposed concessions) in the past two years, and over 84% at some point during the past 40 years. We project that the recent rapid proliferation of hydrocarbon zones will lead to a second exploration boom, characterized by over 20 000 km of new seismic testing and construction of over 180 new exploratory wells in remote, intact, and sensitive forest areas. As the Peruvian Amazon oil frontier rapidly expands, we conclude that a rigorous policy debate is urgently needed in order to avoid the major environmental impacts associated with the first exploration boom of the 1970s and to minimize the social conflict that recently led to deadly encounters between indigenous protesters and government forces.

  7. Gravity and magnetic investigations along the Peruvian continental margin

    NASA Astrophysics Data System (ADS)

    Heinbockel, R.; Dehghani, G. A.; Huebscher, Ch.

    2003-04-01

    This work presents the first three-dimensional gravity and magnetic investigation along the convergent Peruvian margin. Three-dimensional magnetic modelling is still a relatively untried and challenging technique. The gravity and magnetic models image nearly the whole margin which has been only partly resolved with geophysical methods up to now. The gravity and magnetic models are constructed for three areas between 7.25°S and 16.75°S and are based on the available wide-angle seismic velocity models (Hampel et al., 2002a; Broser et al., 2002). The continental margin is characterised by positive free-air anomalies of varying amplitudes, indicating that the margin has been shaped by the subduction of different features on the Nazca Plate. A comparison of the shipboard gravity measurements with the satellite data ensures that the data compiled from different marine surveys are compatible. In the Yaquina Area (7.25°S to 11°S) gravity anomalies caused by the Trujillo Trough and the Mendaña Fracture Zone are successfully modelled with remarkable undulations in the layer geometry of the oceanic crust. Along the continental margin, especially in the Lima Area (10.50°S to 14.40°S), strong undulations of the lower continental crust influence the upper sedimentary layers and support the development of basins along the Peruvian margin. The theory stating that the Peruvian margin is uplifted by the subducting Nazca Ridge (Kulm et al., 1988; Hagen &Moberly, 1994) is supported by gravity modelling. Consequently the buoyant Nazca Ridge is, at least partly, responsible for the extended region of flat subduction. The thickened and slightly asymmetrical crust of the Nazca Ridge is envisaged in gravity modelling. In the Nazca Ridge Area (14.25°S to 16.75°S) no accretionary prism is modelled. We conclude that the ridge is eroding the continental margin; furthermore the subduction of eroded sediments is probable. Gravity modelling suggests that the Nazca Ridge has fractured the

  8. Molecular characterization of an earliest cacao (Theobroma cacao L.) collection from Peruvian Amazon using microsatllite DNA markers

    USDA-ARS?s Scientific Manuscript database

    Cacao (Theobroma cacao L.) is indigenous to the Amazon region of South America. The Peruvian Amazon harbors a large number of diverse cacao populations. Since the 1930s, several numbers of populations have been collected from the Peruvian Amazon and maintained as ex situ germplasm repositories in ...

  9. Structural characterization of Peruvian carrot (Arracacia xanthorrhiza) starch and the effect of annealing on its semicrystalline structure.

    PubMed

    Rocha, Thais S; Cunha, Verena A G; Jane, Jay-Lin; Franco, Celia M L

    2011-04-27

    Structural characteristics of native and annealed Peruvian carrot (Arracacia xanthorrhiza) starches were determined and compared to those of cassava and potato starches. Peruvian carrot starch presented round and irregular shaped granules, low amylose content and B-type X-ray pattern. Amylopectin of this starch contained a large proportion of long (DP > 37) and short (DP 6-12) branched chains. These last ones may contribute to its low gelatinization temperature. After annealing, the gelatinization temperatures of all starches increased, but the ΔH and the crystallinity increased only in Peruvian carrot and potato starches. The annealing process promoted a higher exposure of Peruvian carrot amylose molecules, which were more quickly attacked by enzymes, whereas amylopectin molecules became more resistant to hydrolysis. Peruvian carrot starch had structural characteristics that differed from those of cassava and potato starches. Annealing affected the semicrystalline structure of this starch, enhancing its crystallinity, mainly due to a better interaction between amylopectin chains.

  10. Titling indigenous communities protects forests in the Peruvian Amazon.

    PubMed

    Blackman, Allen; Corral, Leonardo; Lima, Eirivelthon Santos; Asner, Gregory P

    2017-04-18

    Developing countries are increasingly decentralizing forest governance by granting indigenous groups and other local communities formal legal title to land. However, the effects of titling on forest cover are unclear. Rigorous analyses of titling campaigns are rare, and related theoretical and empirical research suggests that they could either stem or spur forest damage. We analyze such a campaign in the Peruvian Amazon, where more than 1,200 indigenous communities comprising some 11 million ha have been titled since the mid-1970s. We use community-level longitudinal data derived from high-resolution satellite images to estimate the effect of titling between 2002 and 2005 on contemporaneous forest clearing and disturbance. Our results indicate that titling reduces clearing by more than three-quarters and forest disturbance by roughly two-thirds in a 2-y window spanning the year title is awarded and the year afterward. These results suggest that awarding formal land titles to local communities can advance forest conservation.

  11. A developmental analysis of generic nouns in Southern Peruvian Quechua.

    PubMed

    Mannheim, Bruce; Gelman, Susan A; Escalante, Carmen; Huayhua, Margarita; Puma, Rosalía

    2010-01-01

    Generic noun phrases (e.g., "Cats like to drink milk") are a primary means by which adults express generalizations to children, yet they pose a challenging induction puzzle for learners. Although prior research has established that English speakers understand and produce generic noun phrases by preschool age, little is known regarding the cross-cultural generality of generic acquisition. Southern Peruvian Quechua provides a valuable comparison because, unlike English, it is a highly inflected language in which generics are marked by the absence rather than the presence of any linguistic markers. Moreover, Quechua is spoken in a cultural context that differs markedly from the highly educated, middle-class contexts within which earlier research on generics was conducted. We presented participants from 5 age groups (3-6, 7-9, 10-12, 14-35, and 36-90 years of age) with two tasks that examined the ability to distinguish generic from non-generic utterances. In Study 1, even the youngest children understood generics as applying broadly to a category (like "all") and distinct from indefinite reference ("some"). However, there was a developmental lag before children understood that generics, unlike "all", can include exceptions. Study 2 revealed that generic interpretations are more frequent for utterances that (a) lack specifying markers and (b) are animate. Altogether, generic interpretations are found among the youngest participants, and may be a default mode of quantification. These data demonstrate the cross-cultural importance of generic information in linguistic expression.

  12. Titling indigenous communities protects forests in the Peruvian Amazon

    PubMed Central

    Blackman, Allen; Corral, Leonardo; Lima, Eirivelthon Santos; Asner, Gregory P.

    2017-01-01

    Developing countries are increasingly decentralizing forest governance by granting indigenous groups and other local communities formal legal title to land. However, the effects of titling on forest cover are unclear. Rigorous analyses of titling campaigns are rare, and related theoretical and empirical research suggests that they could either stem or spur forest damage. We analyze such a campaign in the Peruvian Amazon, where more than 1,200 indigenous communities comprising some 11 million ha have been titled since the mid-1970s. We use community-level longitudinal data derived from high-resolution satellite images to estimate the effect of titling between 2002 and 2005 on contemporaneous forest clearing and disturbance. Our results indicate that titling reduces clearing by more than three-quarters and forest disturbance by roughly two-thirds in a 2-y window spanning the year title is awarded and the year afterward. These results suggest that awarding formal land titles to local communities can advance forest conservation. PMID:28373565

  13. [Tolerance and digestibility of Peruvian "common foods" in malnourished infants].

    PubMed

    López de Romaña, G L; Creed, H M; Graham, G G

    1978-12-01

    Six diets were prepared based on commonly used Peruvian foods, mainly of vegetable origin, which were offered to eight infants (mean age: 12.8 +/- 8.2 months) recovering from malnutrition. The purpose of this study was to evaluate the acceptability, tolerance and digestibility of the diets in question. Five were prepared with a potato and wheat base (noodle) and the sixth with a quinua-oats base. The acceptability and tolerance was satisfacotry, allowing maintenance of an adequate calorie and protein intake in all patients except one. On the quinua-oats based diet, the mean apparent absorption of nitrogen and fat was significantly lower (P less than 0.05) than in the case of the other diets. The increase in height coefficient (height age/chronological age X 100) and weight/age proved to be adequate during the study, except in the three youngest patients. The authors consider that this type of diets (potato-wheat based) can be recommended for infant feeding after the first year of life, and that the quinua-oats based diet still needs a more thorough evaluation prior to recommending its use.

  14. The Association between Socioeconomic Status and Obesity in Peruvian Women

    PubMed Central

    Poterico, J.A.; Stanojevic, S.; Ruiz, P.; Bernabe-Ortiz, A.; Miranda, J. J.

    2012-01-01

    Historically in developing countries, the prevalence of obesity has been greater in more advantaged socioeconomic groups. However, in recent years the association between socioeconomic status (SES) and obesity has changed and varies depending on the country’s development stage. This study examines the relationship between SES and obesity using two indicators of SES: education or possession assets. Using the cross-sectional 2008 National Demographic and Family Health Survey of Peru (ENDES 2008) we investigated this relationship in women aged 15 to 49 years living in rural and urban settings. Descriptive, linear and logistic regressions analyses were conducted accounting for the multi-staged nature of the sampling design. The overall prevalence of obesity in this study was 14.1% (95%CI: 13.3–14.8); 8.4% (95%CI: 7.5–9.3) in rural areas and 16.2% (95%CI: 15.2–17-2) in urban areas. Wealthier women were more likely to be obese, and this association was stronger in rural areas. Conversely, more educated women were less likely to be obese, especially in urban areas. The distribution of obesity in Peruvian women is strongly related to socioeconomic position, and differs whether measured as possession assets or by level of education. These findings could have important implications for policy development in Peru. PMID:21959344

  15. Subsistence economy of el paraiso, an early peruvian site.

    PubMed

    Quilter, J; E, B O; Pearsall, D M; Sandweiss, D H; Jones, J G; Wing, E S

    1991-01-18

    Studies of food remains from the Preceramic monumental site of E1 Paraíso, Peru (1800 to 1500 B.C.), have shed new light on a debate regarding the relative importance of seafood versus terrestrial resources and the role of cultigens in subsistence economies during the early development of Peruvian civilization. Fish was the primary animal food at the site whereas plant foods consisted of a mixture of cultivated resources (squashes, beans, peppers, and jicama) with an additional reliance on fruits (guava, lucuma, and pacae). Wild plants, especially the roots of sedges and cat-tail, also may have accounted for a substantial part of the diet. Cotton was a chief crop, used in making fishing tackle and the textiles that served as clothing and items of high value and status. As an example of the beginnings of civilization, El Paraíso is a case in which impressive architecture was built on a relatively simple subsistence economy and energy was expended in the production of resources useful in local and regional exchange systems.

  16. Epidemiology of Taeniasis and Cysticercosis in a Peruvian Village

    PubMed Central

    Diaz, F.; Garcia, H. H.; Gilman, R. H.; Gonzales, A. E.; Castro, M.; Tsang, V. C. W.; Pilcher, J. B.; Vasquez, L. E.; Lescano, M.; Carcamo, C.; Madico, G.; Miranda, E.

    2011-01-01

    To determine the prevalence of cysticercosis in a rural area where the disease is endemic, the authors studied the seroepidemiology of human and porcine cysticercosis in a Peruvian jungle community (Maceda, Peru) in 1988 using an enzyme-linked immunoelectrotransfer blot (EITB) assay. Of the 371 sampled inhabitants, 30 (8%) were seropositive, most of whom were asymptomatic. After niclosamide therapy, four Taenia species worms were identified in the seropositive group, compared with one in the control group (p = 0.06). Pigs were frequently infected: 44 of 133 (33%) were found positive for Taenia by tongue examination and 57 of 133 (43%) were positive by EITB. In 69% of the sampled households that had pigs, there was at least one seropositive pig. The number of pigs diagnosed positive by the tongue examination was significantly greater in households that had latrines than in those that did not. Cysticercosis is a common but usually asymptomatic infection that affects both humans and pigs in the high jungle areas of Peru. PMID:1585900

  17. Dermatoglyphics of a high altitude Peruvian population and interpopulation comparisons.

    PubMed

    Baca, O R; Del Valle Mendoza, L; Guerrero, N A

    2001-01-01

    Studies of genetic structures of Andean human populations have not been numerous, even though these studies could be used to answer questions concerning migration routes of the indigenous peoples who populated America. Such studies could provide basic genetic information and clarify uncertainties surrounding genetic relatedness of South American indigenous peoples. This present work describes, quantifies, and analyzes the digital and palmar dermatoglyphics of 120 people in the community of San Pedro de Casta, Perú. The results were then compared using distance analysis to all other Peruvian population values studied to date and other South American populations. The dermatoglyphic indicators studied were the distribution of digital pattern frequencies, the total ridge counts (TRC), the pattern intensity index (PII), the atd angle, and the a-b ridge counts. The results did not show statistically significant differences for digital patterns between hands, neither within a sex nor between sexes. The means and standard deviations of PII and TRC were 12.32 +/- 3.97 and 112.18 +/- 45.09, respectively. The means and standard deviations for the other two indicators were the following: atd angle, 94.85 degrees +/- 12.33; and a-b ridge counts, 81.57 +/- 9.06. The distance analyses results suggest the existence of two different genetic lines among high altitude populations, as well as the need for further research.

  18. Absence of infection with human immunodeficiency virus in Peruvian prostitutes.

    PubMed

    Golenbock, D T; Guerra, J; Pfister, J; Golubjatnikov, R; Tejada, A; Abugattas, J; Kemper, R; Maki, D G

    1988-12-01

    We serologically tested 140 female prostitutes (mean age, 30 years) from the port city of Callao, Peru, for evidence of infection with human immunodeficiency virus (HIV), Chlamydia trachomatis, Treponema pallidum, herpes simplex viruses (HSV) I and II, and hepatitis B virus. The women had worked as prostitutes for an average of 5 years; one-fourth serviced foreign visitors exclusively, mainly sailors. Only 4 women used condoms, and only 1 woman gave a history of parenteral narcotic abuse, although 53% were regularly exposed to unsterile needles outside the medical setting for injections of vitamins, antibiotics, or steroids; another 29% are thought to probably use unsterile needles. None of the 140 prostitutes screened was seropositive for HIV, despite a very high prevalence of antibody to T. pallidum (24%), C. trachomatis (97%), HSV I and II (100%), and hepatitis B (51%); 5% were HbsAg positive. These data indicate that HIV has not yet been introduced into female prostitutes in the Peruvian port city. We believe that widespread use of unsterile needles in developing countries, such as Peru, represents a serious health threat and will amplify the spread of HIV, once introduced.

  19. The association between socioeconomic status and obesity in Peruvian women.

    PubMed

    Poterico, Julio A; Stanojevic, Sanja; Ruiz-Grosso, Paulo; Bernabe-Ortiz, Antonio; Miranda, J Jaime

    2012-11-01

    Historically in developing countries, the prevalence of obesity has been greater in more advantaged socioeconomic groups. However, in recent years the association between socioeconomic status (SES) and obesity has changed and varies depending on the country's development stage. This study examines the relationship between SES and obesity using two indicators of SES: education or possession assets. Using the cross-sectional 2008 National Demographic and Family Health Survey of Peru (ENDES 2008), we investigated this relationship in women aged 15-49 years living in rural and urban settings. Descriptive, linear and logistic regressions analyses were conducted accounting for the multistage nature of the sampling design. The overall prevalence of obesity in this study was 14.1% (95% confidence interval (CI): 13.3-14.8); 8.4% (95% CI: 7.5-9.3) in rural areas and 16.2% (95% CI: 15.2-17.2) in urban areas. Wealthier women were more likely to be obese, and this association was stronger in rural areas. Conversely, more educated women were less likely to be obese, especially in urban areas. The distribution of obesity in Peruvian women is strongly related to socioeconomic position, and differs whether measured as possession assets or by level of education. These findings could have important implications for policy development in Peru.

  20. Meteorological constraints on oceanic halocarbons above the Peruvian Upwelling

    NASA Astrophysics Data System (ADS)

    Fuhlbrügge, S.; Quack, B.; Atlas, E.; Fiehn, A.; Hepach, H.; Krüger, K.

    2015-07-01

    Halogenated very short lived substances (VSLS) are naturally produced in the ocean and emitted to the atmosphere. Recently, oceanic upwelling regions in the tropical East Atlantic were identified as strong sources of brominated halocarbons to the atmosphere. During a cruise of R/V METEOR in December 2012 the oceanic sources and emissions of various halogenated trace gases and their mixing ratios in the marine atmospheric boundary layer (MABL) were investigated above the Peruvian Upwelling for the first time. This study presents novel observations of the three VSLS bromoform, dibromomethane and methyl iodide together with high resolution meteorological measurements and Lagrangian transport modelling. Although relatively low oceanic emissions were observed, except for methyl iodide, surface atmospheric abundances were elevated. Radiosonde launches during the cruise revealed a low, stable MABL and a distinct trade inversion above acting both as strong barriers for convection and trace gas transport in this region. Significant correlations between observed atmospheric VSLS abundances, sea surface temperature, relative humidity and MABL height were found. We used a simple source-loss estimate to identify the contribution of oceanic emissions to observed atmospheric concentrations which revealed that the observed marine VSLS abundances were dominated by horizontal advection below the trade inversion. The observed VSLS variations can be explained by the low emissions and their accumulation under different MABL and trade inversion conditions. This study confirms the importance of oceanic upwelling and trade wind systems on creating effective transport barriers in the lower atmosphere controlling the distribution of VSLS abundances above ocean upwelling regions.

  1. Epidemiology of Echinococcus granulosus infection in the central Peruvian Andes.

    PubMed Central

    Moro, P. L.; McDonald, J.; Gilman, R. H.; Silva, B.; Verastegui, M.; Malqui, V.; Lescano, G.; Falcon, N.; Montes, G.; Bazalar, H.

    1997-01-01

    The prevalence of human, canine, and ovine echinococcosis was determined in an endemic area of the Peruvian Andes where control programmes have not been operational since 1980. Prevalence of infection in humans was determined using portable ultrasound, chest X-rays, and an enzyme-linked immunoelectrotransfer blot (EITB) assay. Canine and ovine echinococcal prevalence was determined by microscopic stool examinations following arecoline purging for tapeworm detection and by examination of the viscera from slaughtered livestock animals, respectively. The prevalence among 407 humans surveyed was 9.1%. The frequency of disease in the liver, lung, and in both organs was 3.4%, 2.0%, and 0.2%, respectively. Portable ultrasound or portable chest X-ray has shown that, compared to adults, children under 11 years had significantly higher seropositive rates without evidence of hydatid disease (P < 0.05). Among the 104 dogs inspected for echinococcus after arecoline purging, 33 (32%) were positive for adult tapeworms. Among the 117 sheep slaughtered at the local abattoir, 102 (87%) had hydatid cysts. The prevalence of human hydatidosis in this endemic area of Peru is one of the highest in the world and nearly five times higher than previously reported in 1980. An increase in echinococcosis prevalence may result after premature cessation of control programmes. PMID:9509628

  2. Seroincidence of porcine T. solium infection in the Peruvian highlands.

    PubMed

    Garcia, H H; Gonzalez, A E; Gavidia, C; Falcon, N; Bernal, T; Verastegui, M; Rodriguez, S; Tsang, V C W; Gilman, R H

    2003-04-15

    We performed repeated serological sampling of pigs in an endemic area of the Peruvian highlands (eight villages) to assess the feasibility of detecting incident cases of Taenia solium infection as indicators of ongoing transmission of the parasite. A total of 2245 samples corresponding to 1548 pigs were collected in three sampling rounds (n=716, 926, and 603, respectively). Village-period specific seroprevalences of antibodies by enzyme-linked immunoelectrotransfer blot (EITB) assay varied from 39% (95% CI: 34, 44) to 76% (95% CI: 72, 79). The prevalence of cysticercosis increased with the age of the pigs (similarly for both sexes). Around 40% of pigs were re-sampled at the end of each 4-month period. Crude incidence risks were 48% (57/120, 95% CI: 43-52) and 58% (111/192, 95% CI: 54-61) for each period. A proportion of seropositive animals became seronegative at the end of each period (23 and 15%). Incidence varied by the village, and the exposure period, and was higher in males than females (but did not differ by age).

  3. Reproduction and population levels of Peruvian Guano Birds, 1980 to 1986

    NASA Astrophysics Data System (ADS)

    Tovar, H.; GuilléN, V.; Cabrera, D.

    1987-12-01

    The three species of guano birds, guanay cormorant (Phalacrocorax bougainvillii), Peruvian booby (Sula variegate), and Peruvian pelican (Pelecanus occidentalis thagus), depend mainly on the Peruvian anchovy (Engraulis ringens) for sustenance. A naturally occurring limitation on the population size of these birds is the oceanographic phenomenon known as "El Niño". The industrialization of the anchovy fishery during the 1960s and 1970s has also affected seabird populations: The annual extraction of huge volumes offish has decreased the availability of food for the guano birds, causing large population fluctuations and considerable changes in the relative abundance of the birds. Because of its great intensity and duration, the 1982-1983 El Niño caused high avian mortality, depressing populations to levels from which they have not yet recovered.

  4. Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom.

    PubMed

    Schneider, Francisco S; Starling, Maria C; Duarte, Clara G; Machado de Avila, Ricardo; Kalapothakis, Evanguedes; Silva Suarez, Walter; Tintaya, Benigno; Flores Garrido, Karin; Seraylan Ormachea, Silvia; Yarleque, Armando; Bonilla, César; Chávez-Olórtegui, Carlos

    2012-11-01

    Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and lethality. The Peruvian anti-bothropic anti-venom displays consistent cross-reactivity with B. andianus venom, by ELISA and Western Blotting and is also effective in neutralizing the venom's toxic activities. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Description of Lutzomyia (Trichophoromyia) nautaensis n. sp. (Diptera: Psychodidae) from the Peruvian Amazon Basin

    PubMed Central

    Fernandez, Roberto; Lopez, Victor; Cardenas, Roldan; Requena, Edwin

    2015-01-01

    A new species of sand fly, which we describe as Lutzomyia (Trichophoromyia) nautaensis n. sp., was collected in the northern Peruvian Amazon Basin. In this region of Peru, cutaneous leishmaniasis is transmitted primarily by anthropophilic sand flies; however, zoophilic sand flies of the subgenus Trichophoromyia may also be incriminated in disease transmission. Detection of Leishmania spp. in Lutzomyia auraensis Mangabeira captured in the southern Peruvian Amazon indicates the potential of this and other zoophilic sand flies for human disease transmission, particularly in areas undergoing urban development. Herein, we describe Lutzomyia (Trichophoromyia) nautaensis n. sp., and report new records of sand flies in Peru. PMID:26335468

  6. Description of Lutzomyia (Trichophoromyia) nautaensis n. sp. (Diptera: Psychodidae) from the Peruvian Amazon Basin.

    PubMed

    Fernandez, Roberto; Lopez, Victor; Cardenas, Roldan; Requena, Edwin

    2015-07-01

    A new species of sand fly, which we describe as Lutzomyia (Trichophoromyia) nautaensis n. sp., was collected in the northern Peruvian Amazon Basin. In this region of Peru, cutaneous leishmaniasis is transmitted primarily by anthropophilic sand flies; however, zoophilic sand flies of the subgenus Trichophoromyia may also be incriminated in disease transmission. Detection of Leishmania spp. in Lutzomyia auraensis Mangabeira captured in the southern Peruvian Amazon indicates the potential of this and other zoophilic sand flies for human disease transmission, particularly in areas undergoing urban development. Herein, we describe Lutzomyia (Trichophoromyia) nautaensis n. sp., and report new records of sand flies in Peru.

  7. Hydroclimatic change disparity of Peruvian Pacific drainage catchments

    NASA Astrophysics Data System (ADS)

    Rau, Pedro; Bourrel, Luc; Labat, David; Frappart, Frédéric; Ruelland, Denis; Lavado, Waldo; Dewitte, Boris; Felipe, Oscar

    2017-09-01

    Peruvian Pacific drainage catchments only benefit from 2% of the total national available freshwater while they concentrate almost 50% of the population of the country. This situation is likely to lead a severe water scarcity and also constitutes an obstacle to economic development. Catchment runoff fluctuations in response to climate variability and/or human activities can be reflected in extreme events, representing a serious concern (like floods, erosion, droughts) in the study area. To document this crucial issue for Peru, we present here an insightful analysis of the water quantity resource variability of this region, exploring the links between this variability and climate and/or anthropogenic pressure. We first present a detailed analysis of the hydroclimatologic variability at annual timescale and at basin scale over the 1970-2008 period. In addition to corroborating the influence of extreme El Niño events over precipitation and runoff in northern catchments, a mean warming of 0.2 °C per decade over all catchments was found. Also, higher values of temperature and potential and actual evapotranspiration were found over northern latitudes. We chose to apply the Budyko-Zhang framework that characterizes the water cycle as a function of climate only, allowing the identification of catchments with significant climatic and anthropogenic influence on water balance. The Budyko-Zhang methodology revealed that 11 out of 26 initial catchments are characterized by low water balance disparity related to minor climatic and anthropogenic influence. These 11 catchments were suitable for identifying catchments with contrasting change in their hydroclimatic behavior using the Budyko trajectories. Our analysis further reveals that six hydrological catchment responses can be characterized by high sensitivity to climate variability and land use changes.

  8. Climate change and potato cropping in the Peruvian Altiplano

    NASA Astrophysics Data System (ADS)

    Sanabria, J.; Lhomme, J. P.

    2013-05-01

    The potential impacts of climate change on potatoes cropping in the Peruvian highlands (Altiplano) is assessed using climate projections for 2071-2100, obtained from the HadRM3P regional atmospheric model of the Hadley Centre. The atmospheric model is run under two different special report on emission scenarios: high CO2 concentration (A2) and moderate CO2 concentration (B2) for four locations situated in the surroundings of Lake Titicaca. The two main varieties of potato cultivated in the area are studied: the Andean potato ( Solanum tuberosum) and the bitter potato ( Solanum juzepczukii). A simple process-oriented model is used to quantify the climatic impacts on crops cycles and yields by combining the effects of temperature on phenology, of radiation and CO2 on maximum yield and of water balance on yield deficit. In future climates, air temperature systematically increases, precipitation tends to increase at the beginning of the rainy season and slightly decreases during the rest of the season. The direct effects of these climatic changes are earlier planting dates, less planting failures and shorter crop cycles in all the four locations and for both scenarios. Consequently, the harvesting dates occur systematically earlier: roughly in January for the Andean potato instead of March in the current situation and in February for the bitter potato instead of April. Overall, yield deficits will be higher under climate change than in the current climate. There will be a strong negative impact on yields for S. tuberosum (stronger under A2 scenario than under B2); the impact on S. juzepczukii yields, however, appears to be relatively mixed and not so negative.

  9. Land Use Change Driven by Gold Mining; Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Swenson, J. J.; Carter, C. E.; domec, J.; Delgado, C. I.

    2011-12-01

    Many factors such as poverty, ineffective institutions and environmental regulations may prevent developing countries from managing how natural resources are extracted to meet a strong market demand. Extraction for some resources has reached such proportions that evidence is measurable from space. We present recent evidence of the global demand for a single commodity and the ecosystem destruction resulting from commodity extraction, recorded by satellites for one of the most biodiverse areas of the world. We find that since 2003, recent mining deforestation in Madre de Dios, Peru is increasing nonlinearly alongside a constant annual rate of increase in international gold price (~18%/yr). We detect that the new pattern of mining deforestation (1915 ha/year, 2006-2009) is outpacing that of nearby settlement deforestation. We show that gold price is linked with exponential increases in Peruvian national mercury imports over time (R2 = 0.93, p = 0.04, 2003- 2009). Given the past rates of increase we predict that mercury imports may more than double for 2011 (~500 t/year). Virtually all of Peru's mercury imports are used in artisanal gold mining. Much of the mining increase is unregulated/ artisanal in nature, lacking environmental impact analysis or miner education. As a result, large quantities of mercury are being released into the atmosphere, sediments and waterways. Other developing countries endowed with gold deposits are likely experiencing similar environmental destruction in response to recent record high gold prices. The increasing availability of satellite imagery ought to evoke further studies linking economic variables with land use and cover changes on the ground.

  10. A developmental analysis of generic nouns in Southern Peruvian Quechua

    PubMed Central

    Mannheim, Bruce; Gelman, Susan A.; Escalante, Carmen; Huayhua, Margarita; Puma, Rosalía

    2010-01-01

    Generic noun phrases (e.g., “Cats like to drink milk”) are a primary means by which adults express generalizations to children, yet they pose a challenging induction puzzle for learners. Although prior research has established that English speakers understand and produce generic noun phrases by preschool age, little is known regarding the cross-cultural generality of generic acquisition. Southern Peruvian Quechua provides a valuable comparison because, unlike English, it is a highly inflected language in which generics are marked by the absence rather than the presence of any linguistic markers. Moreover, Quechua is spoken in a cultural context that differs markedly from the highly educated, middle-class contexts within which earlier research on generics was conducted. We presented participants from 5 age groups (3-6, 7-9, 10-12, 14-35, and 36-90 years of age) with two tasks that examined the ability to distinguish generic from non-generic utterances. In Study 1, even the youngest children understood generics as applying broadly to a category (like “all”) and distinct from indefinite reference (“some”). However, there was a developmental lag before children understood that generics, unlike “all”, can include exceptions. Study 2 revealed that generic interpretations are more frequent for utterances that (a) lack specifying markers and (b) are animate. Altogether, generic interpretations are found among the youngest participants, and may be a default mode of quantification. These data demonstrate the cross-cultural importance of generic information in linguistic expression. PMID:21779154

  11. Depressive Symptoms and Migraine Comorbidity among Pregnant Peruvian Women

    PubMed Central

    May Cripe, Swee; Sanchez, Sixto; Lam, Nelly; Sanchez, Elena; Ojeda, Nely; Tacuri, Silvia; Segura, Carmen; Williams, Michelle A.

    2009-01-01

    Background Migraine and depression are known to be comorbid conditions in non-pregnant women and men. However, the migraine-depression comorbidity among pregnant women, particularly women in developing countries has not been evaluated. Therefore, we evaluated the migraine-depressive symptom relationship in a large cohort of pregnant Peruvian women. Methods Women who delivered singleton infants (N=2,293) at the Instituto Nacional Materno Perinatal, Lima, Peru were interviewed during the postpartum hospital stay. Women were asked questions related to their lifetime and pregnancy experiences with headaches and migraines. Responses to these questions enabled the classification of “probable” and “strict” migraines according to the International Headache Society diagnostic criteria. Depressive symptoms were assessed using the nine-item Patient Health Questionnaire Depression Subset. Logistic regression procedures were used to estimate adjusted odds ratios (AORs) and 95% confidence intervals (CIs). Results Approximately 32% of the women reported a history of migraine, while 41% reported experiencing moderate to severe depressive symptoms during pregnancy. Compared with women without a history of migraine, women with strict migraine had AORs of 2.12 (95% CI 1.54–2.93), 1.85 (95% CI 1.16–2.96) and 2.23 (95% CI 1.08–4.62) for moderate, moderately severe and severe depressive symptoms, respectively. Conclusion This is the first report of a cross-sectional association between migraine and depressive symptoms in pregnant women. If our findings are confirmed, pregnant women with a history of migraine may benefit from increased vigilance for screening and treating depressive symptoms. PMID:19695709

  12. Deglaciation and Holocene climate change in the western Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Weng, Chengyu; Bush, Mark B.; Curtis, Jason H.; Kolata, Alan L.; Dillehay, Tom D.; Binford, Michael W.

    2006-07-01

    Pollen, charcoal, magnetic susceptibility, and bulk density data provide the first paleoecological record spanning the last 33,000 years from the western cordillera of the Peruvian Andes. Sparse super-puna vegetation existed before 30,000 cal yr B.P. around Lake Compuerta (3950 m elevation), prior to a sedimentary hiatus that lasted until c. 16,200 cal yr B.P. When sedimentation resumed, a glacial foreland or super-puna flora is represented in which Polylepis was a significant element. Glacial outwash, marked by high sedimentary magnetic susceptibility, increased from c.16,200 cal yr B.P. and reached a peak at c. 13,200 cal yr B.P. Between c. 12,500 cal yr B.P. and 10,000 cal yr B.P., magnetic susceptibility was reduced. Vegetation shifts suggest a cool dry time, consistent with regional descriptions of the Younger Dryas event. Deglaciation resumes by 10,000 cal yr B.P. and the last ice is lost from the catchment at ˜7500 cal yr B.P. During the early Holocene warm and dry period between 10,000 and 5500 cal yr B.P., Alnus expanded in downslope forests. Alnus declined in abundance at 5500 cal yr B.P. when wetter and cooler conditions returned and human activity intensified. Maize ( Zea mays) pollen first occurred in the core at ˜2600 cal yr B.P., indicating a minimum age for local agriculture. An increase in Alnus pollen abundance at ˜1000 cal yr B.P. could be due to human activity or perhaps due to a regional climate change associated with cultural turnover elsewhere in the Andes at this time.

  13. De-demonizing the VRAEM: A Peruvian-Cocalero Area.

    PubMed

    Ferreira, Francisco

    2016-01-02

    The valley of the rivers Apurímac, Ene, and Mantaro (VRAEM) is the main center of coca production in Peru. This is a jungle area located between southern highland regions, and is notorious for the presence of drug-trafficking and the last remnants of Shining Path guerrillas. As a result, it occupies a central place in security policies in Peru, and has been "demonized" in the national imaginary. This article explores the current situation, recent history, and most important collectives of the VRAEM, challenging stereotypes about it. The article is based on short-term fieldwork undertaken in the VRAEM in March 2008, and long-term research conducted in Ayacucho in 2008-2009; and it is contextualized in relation to the literature on coca producing areas and drug policies. The negative image of the VRAEM started in the context of the 1980s-1990s coca boom and Peruvian armed conflict. State policies in the area since then have been mainly based on militarization and repression, contributing to maintain that negative image, which differs of a complex and nuanced local reality. A coca eradication campaign started in 2014, bringing major changes. The negative image of the VRAEM is largely unfair, and has been mainly based on stereotypes and prejudices. This negative stereotyping contributes to justify and maintain inefficient and pernicious state policies in the area, and to criminalize local people. There is an urgent need for fieldwork-based studies in the area to counteract those negative stereotypes and monitor current events.

  14. Trading forests for yields in the Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Gibbs, Holly

    2012-03-01

    Our knowledge of how agriculture expands, and the types of land it replaces, is remarkably limited across the tropics. Most remote-sensing studies focus on the net gains and losses in forests and agricultural land rather than the land-use transition pathways (Gibbs et al 2010). Only a handful of studies identify land sources for new croplands or plantations, and then only for farming systems aggregated together (e.g., Koh and Wilcove 2008, Morton et al 2006, Gibbs et al 2010). Gutiérrez-Vélez et al (2011), however, have taken a leap forward by tracking the different expansion pathways for smallholder and industrial oil palm plantations. Using a combination of Landsat, MODIS and field surveys, they investigate whether higher yields in new agricultural lands spare forests in the Peruvian Amazon and in a smaller focus area in the Ucayali region. Across the Peruvian Amazon, they show that between 2000 and 2010, new high-yield oil palm plantations replaced forests 72% of the time and accounted for 1.3% of total deforestation, with most expansion occurring after 2006. Gutiérrez-Vélez et al went further in the Ucayali region and compared land sources for new high-yield and low-yield plantations. Expansion of higher-yield agricultural lands should logically reduce the total area needed for production, thus potentially sparing forests. In the Ucayali focus area, expansion of high-yield oil palm did convert less total land area but more forest was cleared than with low-yield expansion. Smaller-scale plantations tended to expand into already cleared areas while industrial-scale plantations traded their greater yields for forests, leading to higher land-clearing carbon emissions per production unit (Gibbs et al 2008). Gutiérrez-Vélez et al show that higher yields may require less land for production but more forest may be lost in the process, and they emphasize the need for stronger incentives for land sparing. The potential land-saving nature of these high

  15. Bilingual Education and Language Use among the Shipibo of the Peruvian Amazon.

    ERIC Educational Resources Information Center

    Tacelosky, Kathleen

    2001-01-01

    Investigates how language choice for education contributes to changes in the way a society views and uses language in the context of the Peruvian Amazon. Oral surveys were administered to Shipibo people in 13 communities along the Ucayali River of eastern Peru where a transition type bilingual education program was introduced several decades ago.…

  16. A Peculiar Mutation Spectrum Emerging from Young Peruvian Patients with Hepatocellular Carcinoma

    PubMed Central

    Marchio, Agnès; Bertani, Stéphane; Rojas Rojas, Teresa; Doimi, Franco; Terris, Benoît; Deharo, Eric; Dejean, Anne; Ruiz, Eloy; Pineau, Pascal

    2014-01-01

    Hepatocellular carcinoma usually afflicts individuals in their later years following longstanding liver disease. In Peru, hepatocellular carcinoma exists in a unique clinical presentation, which affects patients around age 25 with a normal, healthy liver. In order to deepen our understanding of the molecular processes ongoing in Peruvian liver tumors, mutation spectrum analysis was carried out on hepatocellular carcinomas from 80 Peruvian patients. Sequencing analysis focused on nine genes typically altered during liver carcinogenesis, i.e. ARID2, AXIN1, BRAF, CTNNB1, NFE2L2, H/K/N-RAS, and TP53. We also assessed the transcription level of factors involved in the control of the alpha-fetoprotein expression and the Hippo signaling pathway that controls contact inhibition in metazoans. The mutation spectrum of Peruvian patients was unique with a major class of alterations represented by Insertions/Deletions. There were no changes at hepatocellular carcinoma-associated mutation hotspots in more than half of the specimens analyzed. Furthermore, our findings support the theory of a consistent collapse in the Hippo axis, as well as an expression of the stemness factor NANOG in high alpha-fetoprotein-expressing hepatocellular carcinomas. These results confirm the specificity of Peruvian hepatocellular carcinoma at the molecular genetic level. The present study emphasizes the necessity to widen cancer research to include historically neglected patients from South America, and more broadly the Global South, where cancer genetics and tumor presentation are divergent from canonical neoplasms. PMID:25502816

  17. Two new nor-triterpene glycosides from peruvian "Uña de Gato" (Uncaria tomentosa).

    PubMed

    Kitajima, Mariko; Hashimoto, Ken-Ichiro; Yokoya, Masashi; Takayama, Hiromitsu; Sandoval, Manuel; Aimi, Norio

    2003-02-01

    Two new 27-nor-triterpene glycosides, tomentosides A (1) and B (2), were isolated from Peruvian "Uña de Gato" (cat's claw, plant of origin: Uncaria tomentosa), a traditional herbal medicine in Peru. Their structures were determined by spectroscopic analysis and chemical interconversions. This is the first report of naturally occurring pyroquinovic acid glycosides.

  18. "Una Nacion Acorralada": Southern Peruvian Quechua Language Planning and Politics in Historical Perspective.

    ERIC Educational Resources Information Center

    Mannheim, Bruce

    1984-01-01

    Outlines history of Spanish colonial policies toward Southern Peruvian Quechua and points out those issues under debate concerning the indigenous languages. The central issue of the "Andean language debate" continues to be whether or not the Quechua have a right to exist as a separate community. (SL)

  19. Bilingual Education and Language Use among the Shipibo of the Peruvian Amazon.

    ERIC Educational Resources Information Center

    Tacelosky, Kathleen

    2001-01-01

    Investigates how language choice for education contributes to changes in the way a society views and uses language in the context of the Peruvian Amazon. Oral surveys were administered to Shipibo people in 13 communities along the Ucayali River of eastern Peru where a transition type bilingual education program was introduced several decades ago.…

  20. East of the Andes: The genetic profile of the Peruvian Amazon populations.

    PubMed

    Di Corcia, T; Sanchez Mellado, C; Davila Francia, T J; Ferri, G; Sarno, S; Luiselli, D; Rickards, O

    2017-06-01

    Assuming that the differences between the Andes and the Amazon rainforest at environmental and historical levels have influenced the distribution patterns of genes, languages, and cultures, the maternal and paternal genetic reconstruction of the Peruvian Amazon populations was used to test the relationships within and between these two extreme environments. We analyzed four Peruvian Amazon communities (Ashaninka, Huambisa, Cashibo, and Shipibo) for both Y chromosome (17 STRs and 8 SNPs) and mtDNA data (control region sequences, two diagnostic sites of the coding region, and one INDEL), and we studied their variability against the rest of South America. We detected a high degree of genetic diversity in the Peruvian Amazon people, both for mtDNA than for Y chromosome, excepting for Cashibo people, who seem to have had no exchanges with their neighbors, in contrast with the others communities. The genetic structure follows the divide between the Andes and the Amazon, but we found a certain degree of gene flow between these two environments, as particularly emerged with the Y chromosome descent cluster's (DCs) analysis. The Peruvian Amazon is home to an array of populations with differential rates of genetic exchanges with their neighbors and with the Andean people, depending on their peculiar demographic histories. We highlighted some successful Y chromosome lineages expansions originated in Peru during the pre-Columbian history which involved both Andeans and Amazon Arawak people, showing that at least a part of the Amazon rainforest did not remain isolated from those exchanges. © 2017 Wiley Periodicals, Inc.

  1. Icon and Idea: A Symbolic Reading of Pictures in a Peruvian Indian Chronicle.

    ERIC Educational Resources Information Center

    Adorno, Rolena

    1979-01-01

    An examination and categorization of over 400 full-page drawings in the 1615 "Nueva coronica y bien gobierno" of Felipe Guaman Poma de Alaya, which details life in the Peruvian Viceroyalty. Explains the function of the illustrations in the text and that of five "signifying attributes" of spatial configuration. (SB)

  2. Molecular characterization of Peruvian Citrus tristeza virus isolates based on 3’UTR sequences

    USDA-ARS?s Scientific Manuscript database

    Citrus in Peru was decimated by quick decline and stem pitting strains of Citrus tristeza virus (CTV). Commercial citrus production in Peru is being restored by use of CTV cross-protection. To characterize the predominant CTV strains involved, Peruvian CTV isolates from “protected” and “non-protecti...

  3. Icon and Idea: A Symbolic Reading of Pictures in a Peruvian Indian Chronicle.

    ERIC Educational Resources Information Center

    Adorno, Rolena

    1979-01-01

    An examination and categorization of over 400 full-page drawings in the 1615 "Nueva coronica y bien gobierno" of Felipe Guaman Poma de Alaya, which details life in the Peruvian Viceroyalty. Explains the function of the illustrations in the text and that of five "signifying attributes" of spatial configuration. (SB)

  4. Prevalence of Mycoplasma haemolamae infection in Peruvian and Chilean llamas and alpacas.

    PubMed

    Tornquist, Susan J; Boeder, Lisa; Rios-Phillips, Carolina; Alarcon, Virgilio

    2010-09-01

    Mycoplasma haemolamae is a hemotropic mycoplasma that affects red blood cells of llamas (Lama glama) and alpacas (Lama pacos). It is variably associated with anemia, and most infections are subclinical. Development of a polymerase chain reaction assay has facilitated detection of this infection in llamas and alpacas in the United States and other countries. Whether the infection occurs in camelids in South America has previously been unknown. The current study documents a 15.8% infection rate among 76 Peruvian llamas, a 19.3% infection rate among Peruvian alpacas at one site, and a 9.26% infection rate in 108 Chilean alpacas from selected herds. All of the camelids tested appeared to be clinically healthy. No gender or species predilection was found. Only 1 positive camelid younger than 18 months was found. Infection is not associated with anemia, and the mean packed cell volume (PCV) in positive Peruvian camelids was slightly higher than the mean PCV in negative Peruvian camelids. In the Chilean alpacas, the positive alpacas had a slightly lower PCV than the negative alpacas, although the mean PCV was not in the anemic range in any of the groups.

  5. Cross-Sectional Comparison of Sleep-Disordered Breathing in Native Peruvian Highlanders and Lowlanders.

    PubMed

    Pham, Luu V; Meinzen, Christopher; Arias, Rafael S; Schwartz, Noah G; Rattner, Adi; Miele, Catherine H; Smith, Philip L; Schneider, Hartmut; Miranda, J Jaime; Gilman, Robert H; Polotsky, Vsevolod Y; Checkley, William; Schwartz, Alan R

    2017-03-01

    Pham, Luu V., Christopher Meinzen, Rafael S. Arias, Noah G. Schwartz, Adi Rattner, Catherine H. Miele, Philip L. Smith, Hartmut Schneider, J. Jaime Miranda, Robert H. Gilman, Vsevolod Y. Polotsky, William Checkley, and Alan R. Schwartz. Cross-sectional comparison of sleep-disordered breathing in native Peruvian highlanders and lowlanders. High Alt Med Biol. 18:11-19, 2017.

  6. Trophic modelling of the Peruvian upwelling ecosystem: Towards reconciliation of multiple datasets

    NASA Astrophysics Data System (ADS)

    Guénette, Sylvie; Christensen, Villy; Pauly, Daniel

    2008-10-01

    In the 1980s, personnel from the Instituto del Mar del Peru collaborated with foreign experts to reconstruct time series of (1) catch and biomass of the Peruvian anchovy Engraulis ringens back to 1953, along with parallel time series of (2) abundance of anchovy predators and competitors, and (3) abiotic parameters indicative of the dynamics of the Peruvian upwelling system. This contribution documents an attempt to build an ecosystem model of the Peruvian upwelling ecosystem and recreate the observed biomass trends through the period 1953-1984, using the Ecopath with Ecosim (EwE) software. The time series of biomass, particularly of Peruvian anchovy and its various predators, are not reproduced by the EwE model based solely on the original parameters. Instead, to model the anchovy abundance fluctuations caused by El Niño and other oceanographic events, it is necessary to include mechanisms that were not part of the original description of the ecosystem, which focused on mass-balance. For example, a switch between large and small phytoplankton appears to be required to induce the observed abundance shifts between sardine and anchovy. Similarly, a ‘mitigating’ relationship must be assumed between bonito ( Sarda chilensis) and seabirds for the 1965 collapse of seabirds to be reproduced by the model. Mechanisms of this sort, here proposed in a very tentative fashion, will have to be firmly established and quantified before a model can successfully explain both the older data series (1953-1984) as done here, and eventually the new series on the Peruvian upwelling system that became available only recently. With a total of now over 50 years of data, this would represent one of the best documented marine ecosystems in the world, matching its status as one of the most productive.

  7. Prevalence of chronic kidney disease in Peruvian primary care setting.

    PubMed

    Herrera-Añazco, Percy; Taype-Rondan, Alvaro; Lazo-Porras, María; Alberto Quintanilla, E; Ortiz-Soriano, Victor Manuel; Hernandez, Adrian V

    2017-07-19

    Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO). Factors associated with CKD were evaluated with Poisson Regression models; these factors included age, gender, type 2 diabetes mellitus (DM2), hypertension (HTN), body mass index (BMI), and uric acid. Associations were described as crude and adjusted prevalence ratios (PR) and their 95% confidence intervals (95% CI). We evaluated 1211 patients (women [59%], mean age 65.8 years [SD: 12.7]). Prevalence of CKD was 18%. Using the estimated glomerular filtration rate (eGFR), the prevalence was 9.3% (95% CI 5.3 - 13.3) in patients without HTN or DM2; 20.2% (95% CI 17.6 - 22.8) in patients with HTN, and 23.9% (95% CI 19.4 - 28.4) in patients with DM2. The most common stages were 1 and 2 with 41.5% and 48%, respectively. Factors associated with CKD in the adjusted analysis were: age in years (PR = 1.03, 95% CI 1.01 - 1.04), DM2 (PR = 3.37, 95% CI 1.09 - 10.39), HTN plus DM2 (PR = 3.90, 95% CI 1.54 - 9.88), and uric acid from 5 to <7 mg/dL (PR = 2.04, 95% CI 1.31 - 3.19) and ≥7 mg/dL (PR = 5.19, 95% CI 3.32 - 8.11). Prevalence of CKD in the primary care setting population was high. CKD is more frequent in the early stages of the disease, and individuals with hypertension, DM2, older age and hyperuricemia have higher prevalence of CKD.

  8. Sources and fate of amino sugars in coastal Peruvian sediments

    NASA Astrophysics Data System (ADS)

    Niggemann, Jutta; Schubert, Carsten J.

    2006-05-01

    Amino sugars are involved in the marine carbon and nitrogen cycles and comprise a geochemically significant fraction of marine organic material (OM). However, information on abundance and distribution of these compounds in marine sediments is scarce. Three sediment cores (<50 cm) from the coastal region off Peru were investigated for concentrations of glucosamine (GlcN), galactosamine (GalN), mannosamine (ManN), and muramic acid (Mur). The sum of the four amino sugars accounted for 1.0-2.4% of organic carbon and 1.9-3.8% of nitrogen in the sediments. At the shallowest (102 m) and the deepest site (1278 m), carbon-normalized concentrations decreased down-core, suggesting preferential degradation of amino sugars compared to bulk sedimentary OM. At the site from the center of the oxygen minimum zone (238 m), amino sugar concentrations were high throughout the core, pointing to enhanced preservation of amino sugars under anoxic conditions. GlcN (44-56 mol%) and GalN (33-42 mol%) were the dominant amino sugars in all investigated samples, while ManN (6-14 mol%) and Mur (1-4 mol%) were significantly less abundant. Mur was predominantly associated with cell wall remains rather than with living bacteria, since bacterial abundances estimated based on Mur concentrations were up to 500 times higher than cell counts reported for sediments from this area. GlcN/GalN-ratios (1.1-1.7) indicated that chitin, a polymer of GlcN, was not a major contributor to the amino sugar pool of the investigated sediments. Furthermore, GlcN/Mur-ratios (13-68) are inconsistent with a predominant contribution of intact peptidoglycan, which exhibits a 1:1-ratio. The present study includes a compilation of previously published information on distribution and abundance of amino sugars in the marine environment. Both concentrations and ratios observed in the Peruvian sediments fall in the range of values reported for OM in water column and sediments from different oceanic regions and water depths

  9. Benthic phosphorus cycling in the Peruvian oxygen minimum zone

    NASA Astrophysics Data System (ADS)

    Lomnitz, Ulrike; Sommer, Stefan; Dale, Andrew W.; Löscher, Carolin R.; Noffke, Anna; Wallmann, Klaus; Hensen, Christian

    2016-03-01

    Oxygen minimum zones (OMZs) that impinge on continental margins favor the release of phosphorus (P) from the sediments to the water column, enhancing primary productivity and the maintenance or expansion of low-oxygen waters. A comprehensive field program in the Peruvian OMZ was undertaken to identify the sources of benthic P at six stations, including the analysis of particles from the water column, surface sediments, and pore fluids, as well as in situ benthic flux measurements. A major fraction of solid-phase P was bound as particulate inorganic P (PIP) both in the water column and in sediments. Sedimentary PIP increased with depth in the sediment at the expense of particulate organic P (POP). The ratio of particulate organic carbon (POC) to POP exceeded the Redfield ratio both in the water column (202 ± 29) and in surface sediments (303 ± 77). However, the POC to total particulate P (TPP = POP + PIP) ratio was close to Redfield in the water column (103 ± 9) and in sediment samples (102 ± 15). This suggests that the relative burial efficiencies of POC and TPP are similar under low-oxygen conditions and that the sediments underlying the anoxic waters on the Peru margin are not depleted in P compared to Redfield. Benthic fluxes of dissolved P were extremely high (up to 1.04 ± 0.31 mmol m-2 d-1), however, showing that a lack of oxygen promotes the intensified release of dissolved P from sediments, whilst preserving the POC / TPP burial ratio. Benthic dissolved P fluxes were always higher than the TPP rain rate to the seabed, which is proposed to be caused by transient P release by bacterial mats that had stored P during previous periods when bottom waters were less reducing. At one station located at the lower rim of the OMZ, dissolved P was taken up by the sediments, indicating ongoing phosphorite formation. This is further supported by decreasing porewater phosphate concentrations with sediment depth, whereas solid-phase P concentrations were comparatively

  10. Population Genetics of Plasmodium vivax in the Peruvian Amazon

    PubMed Central

    Delgado-Ratto, Christopher; Gamboa, Dionicia; Soto-Calle, Veronica E.; Van den Eede, Peter; Torres, Eliana; Sánchez-Martínez, Luis; Contreras-Mancilla, Juan; Rosanas-Urgell, Anna; Rodriguez Ferrucci, Hugo; Llanos-Cuentas, Alejandro; Erhart, Annette

    2016-01-01

    Background Characterizing the parasite dynamics and population structure provides useful information to understand the dynamic of transmission and to better target control interventions. Despite considerable efforts for its control, vivax malaria remains a major health problem in Peru. In this study, we have explored the population genetics of Plasmodium vivax isolates from Iquitos, the main city in the Peruvian Amazon, and 25 neighbouring peri-urban as well as rural villages along the Iquitos-Nauta Road. Methodology/ Results From April to December 2008, 292 P. vivax isolates were collected and successfully genotyped using 14 neutral microsatellites. Analysis of the molecular data revealed a similar proportion of monoclonal and polyclonal infections in urban areas, while in rural areas monoclonal infections were predominant (p = 0.002). Multiplicity of infection was higher in urban (MOI = 1.5–2) compared to rural areas (MOI = 1) (p = 0.003). The level of genetic diversity was similar in all areas (He = 0.66–0.76, p = 0.32) though genetic differentiation between areas was substantial (PHIPT = 0.17, p<0.0001). Principal coordinate analysis showed a marked differentiation between parasites from urban and rural areas. Linkage disequilibrium was detected in all the areas (IAs = 0.08–0.49, for all p<0.0001). Gene flow among the areas was stablished through Bayesian analysis of migration models. Recent bottleneck events were detected in 4 areas and a recent parasite expansion in one of the isolated areas. In total, 87 unique haplotypes grouped in 2 or 3 genetic clusters described a sub-structured parasite population. Conclusion/Significance Our study shows a sub-structured parasite population with clonal propagation, with most of its components recently affected by bottleneck events. Iquitos city is the main source of parasite spreading for all the peripheral study areas. The routes of transmission and gene flow and the reduction of the parasite population described

  11. Benthic nitrogen cycling traversing the capitalize peruvian oxygen minimum zone

    NASA Astrophysics Data System (ADS)

    Bohlen, L.; Dale, A. W.; Sommer, S.; Mosch, T.; Hensen, C.; Noffke, A.; Scholz, F.; Wallmann, K.

    2011-10-01

    Benthic nitrogen (N) cycling was investigated at six stations along a transect traversing the Peruvian oxygen minimum zone (OMZ) at 11°S. An extensive dataset including porewater concentration profiles and in situ benthic fluxes of nitrate (NO 3-), nitrite (NO 2-) and ammonium (NH 4+) was used to constrain a 1-D reaction-transport model designed to simulate and interpret the measured data at each station. Simulated rates of nitrification, denitrification, anammox and dissimilatory nitrate reduction to ammonium (DNRA) by filamentous large sulfur bacteria (e.g. Beggiatoa and Thioploca) were highly variable throughout the OMZ yet clear trends were discernible. On the shelf and upper slope (80-260 m water depth) where extensive areas of bacterial mats were present, DNRA dominated total N turnover (⩽2.9 mmol N m -2 d -1) and accounted for ⩾65% of NO 3- + NO 2- uptake by the sediments from the bottom water. Nonetheless, these sediments did not represent a major sink for dissolved inorganic nitrogen (DIN = NO 3- + NO 2- + NH 4+) since DNRA reduces NO 3- and, potentially NO 2-, to NH 4+. Consequently, the shelf and upper slope sediments were recycling sites for DIN due to relatively low rates of denitrification and high rates of ammonium release from DNRA and ammonification of organic matter. This finding contrasts with the current opinion that sediments underlying OMZs are a strong sink for DIN. Only at greater water depths (300-1000 m) did the sediments become a net sink for DIN. Here, denitrification was the major process (⩽2 mmol N m -2 d -1) and removed 55-73% of NO 3- and NO 2- taken up by the sediments, with DNRA and anammox accounting for the remaining fraction. Anammox was of minor importance on the shelf and upper slope yet contributed up to 62% to total N 2 production at the 1000 m station. The results indicate that the partitioning of oxidized N (NO 3-, NO 2-) into DNRA or denitrification is a key factor determining the role of marine sediments as DIN

  12. Genetic variation and recurrent parasitaemia in Peruvian Plasmodium vivax populations

    PubMed Central

    2014-01-01

    Background Plasmodium vivax is a predominant species of malaria in parts of South America and there is increasing resistance to drugs to treat infections by P. vivax. The existence of latent hypnozoites further complicates the ability to classify recurrent infections as treatment failures due to relapse, recrudescence of hyponozoites or re-infections. Antigen loci are putatively under natural selection and may not be an optimal molecular marker to define parasite haplotypes in paired samples. Putatively neutral microsatellite loci, however, offer an assessment of neutral haplotypes. The objective here was to assess the utility of neutral microsatellite loci to reconcile cases of recurrent parasitaemia in Amazonian P. vivax populations in Peru. Methods Patient blood samples were collected from three locations in or around Iquitos in the Peruvian Amazon. Five putatively neutral microsatellite loci were characterized from 445 samples to ascertain the within and amongst population variation. A total of 30 day 0 and day of recurrent parasitaemia samples were characterized at microsatellite loci and five polymorphic antigen loci for haplotype classification. Results The genetic diversity at microsatellite loci was consistent with neutral levels of variation measured in other South American P. vivax populations. Results between antigen and microsatellite loci for the 30 day 0 and day of recurrent parasitaemia samples were the same for 80% of the pairs. The majority of non-concordant results were the result of differing alleles at microsatellite loci. This analysis estimates that 90% of the paired samples with the same microsatellite haplotype are unlikely to be due to a new infection. Conclusions A population-level approach was used to yield a better estimate of the probability of a new infection versus relapse or recrudescence of homologous hypnozoites; hypnozoite activation was common for this cohort. Population studies are critical with the evaluation of genetic

  13. New oleanan-type triterpene and cincholic acid glycosides from Peruvian "Uña de Gato" (Uncaria tomentosa).

    PubMed

    Kitajima, Mariko; Hashimoto, Ken-Ichiro; Sandoval, Manuel; Aimi, Norio; Takayama, Hiromitsu

    2004-10-01

    A new oleanan-type triterpene and three new cincholic acid glycosides were isolated from Peruvian "Una de Gato" (Cat's claw, plant of origin: Uncaria tomentosa), a traditional herbal medicine in Peru. Their structures were determined by spectroscopic analysis.

  14. Partial in vitro analysis of toxic and antigenic activities of eleven Peruvian pitviper snake venoms.

    PubMed

    Guerra-Duarte, C; Lopes-Peixoto, J; Fonseca-de-Souza, B R; Stransky, S; Oliveira, D; Schneider, F S; Lopes-de-Souza, L; Bonilla, C; Silva, W; Tintaya, B; Yarleque, A; Chávez-Olórtegui, C

    2015-12-15

    This work used eleven Peruvian snake venoms (Bothrops andianus, Bothrops atrox, Bothrops barnetti, Bothrops castelnaudi, Bothriopsis chloromelas, Bothrocophias microphthalmus, Bothrops neuwiedi, Bothriopsis oligolepis, Bothriopsis peruviana, Bothrops pictus and Bothriopsis taeniata) to perform in vitro experimentation and determine its main characteristics. Hyaluronidase (HYAL), phospholipase A2 (PLA2), snake venom metalloproteinase (SVMP), snake venom serine protease (SVSP) and L-amino acid oxidase (LAAO) activities; toxicity by cell viability assays using MGSO3, VERO and HeLa cell lineages; and crossed immunoreactivity with Peruvian (PAV) and Brazilian (BAV) antibothropic polyvalent antivenoms, through ELISA and Western Blotting assays, were determined. Results show that the activities tested in this study were not similar amongst the venoms and each species present their own peculiarities, highlighting the diversity within Bothrops complex. All venoms were capable of reducing cell viability of all tested lineages. It was also demonstrated the crossed recognition of all tested venoms by both antivenoms.

  15. HLA class I and class II allele distribution in the Peruvian population.

    PubMed

    de Pablo, R; Beraún, Y; Nieto, A; Calzada, J E; Rementería, M C; Sanz, L; López-Nevot, M A; Martín, J

    2000-12-01

    The distribution of HLA-A, -B, -C, -DRB1 and -DQB1 alleles in the Peruvian population was studied and compared with those of other populations in order to provide further information about their anthropological origin. Our data are consistent with the Mestizo character of this population. In terms of genetic distance Peruvians are closest to Bolivians, which is in agreement with the geographical location and the cultural and anthropological background of the two human groups. Several HLA-B alleles originally described in genetically isolated Amerindian tribes are also present in the sample studied here. This fact and the reported finding of these alleles in several Amerindian groups suggests that they were present in the first wave of humans that populated South America (Paleoindians) before they split to give rise to the different South American tribes.

  16. High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy

    PubMed Central

    Zammarchi, Lorenzo; Tortoli, Enrico; Borroni, Emanuele; Bartalesi, Filippo; Strohmeyer, Marianne; Baretti, Simonetta; Simonetti, Maria Tullia; Liendo, Carola; Santini, Maria Grazia; Rossolini, Gian Maria; Gotuzzo, Eduardo; Bartoloni, Alessandro

    2014-01-01

    Tuberculosis is a leading cause of morbidity for Peruvian migrants in Florence, Italy, where they account for about 20% of yearly diagnosed cases. A retrospective study on cases notified in Peruvian residents in Florence in the period 2001-2010 was carried out and available Mycobacterium tuberculosis strains were genotyped (MIRU-VNTR-24 and Spoligotyping). One hundred thirty eight cases were retrieved. Genotyping performed in 87 strains revealed that 39 (44.8%) belonged to 12 clusters. Assuming that in each cluster the transmission of tuberculosis from the index case took place in Florence, a large proportion of cases could be preventable by improving early diagnosis of contagious cases and contact tracing. PMID:25568758

  17. Kinship Paths To and From the New Europe: A Unified Analysis of Peruvian Adoption and Migration

    PubMed Central

    Leinaweaver, Jessaca B.

    2013-01-01

    This article compares migrants and adoptees of Peruvian origin residing in Europe by focusing on their respective movements out of and return to the sending country of Peru. First, it analyzes family-based reunifications by drawing on a framework from studies of adoption and kinship. Juxtaposing the experiences of adoptees with those of migrants reveals how migration, too, may be steeped in concerns about kin ties. Next, it analyzes returns of adult adoptees using a template modeled on migrant returns, focusing on the centrality of the notion of contribution. The article shows how migrants and adoptees contest the constraints of European nation-state definitions of kinship intended to limit migration. It is based on recent research with Peruvian migrants and adoptees in Spain, as well as longer-term research in Peru on migration and adoption. PMID:24443664

  18. Identification of two novel Rotavirus A genotypes, G35 and P[50], from Peruvian alpaca faeces.

    PubMed

    Rojas, Miguel A; Gonçalves, Jorge Luiz S; Dias, Helver G; Manchego, Alberto; Santos, Norma

    2017-09-01

    Rotavirus A (RVA) Alp11B was detected from a neonatal Peruvian alpaca presenting with diarrhea, and the Alp11B VP7, VP4, VP6, NSP4, and NSP5 genes were sequenced. The partial genotype constellation of this strain, RVA/Alpaca-wt/PER/Alp11B/2010, was determined to be G35-P[50]-I13-E16-H6. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Patterns of GPS tracks suggest nocturnal foraging by incubating Peruvian pelicans (Pelecanus thagus).

    PubMed

    Zavalaga, Carlos B; Dell'Omo, Giacomo; Becciu, Paolo; Yoda, Ken

    2011-01-01

    Most seabirds are diurnal foragers, but some species may also feed at night. In Peruvian pelicans (Pelecanus thagus), the evidence for nocturnal foraging is sparse and anecdotal. We used GPS-dataloggers on five incubating Peruvian pelicans from Isla Lobos de Tierra, Perú, to examine their nocturnality, foraging movements and activities patterns at sea. All instrumented pelicans undertook nocturnal trips during a 5-7 day tracking period. Eighty-seven percent of these trips (n = 13) were strictly nocturnal, whereas the remaining occurred during the day and night. Most birds departed from the island after sunset and returned a few hours after sunrise. Birds traveled south of the island for single-day trips at a maximum range of 82.8 km. Overall, 22% of the tracking period was spent at sea, whereas the remaining time was spent on the island. In the intermediate section of the trip (between inbound and outbound commutes), birds spent 77% of the trip time in floating bouts interspersed by short flying bouts, the former being on average three times longer than the latter. Taken together, the high sinuosity of the bird's tracks during floating bouts, the exclusively nocturnal trips of most individuals, and the fact that all birds returned to the island within a few hours after sunrise suggest that pelicans were actively feeding at night. The nocturnal foraging strategy of Peruvian pelicans may reduce food competition with the sympatric and strictly diurnal Guanay cormorants (Phalacrocorax bougainvillii), Peruvian boobies (Sula variegata) and Blue-footed boobies (S. nebouxii), which were present on the island in large numbers. Likewise, plankton bioluminescence might be used by pelicans as indirect cues to locate anchovies during their upward migration at night. The foraging success of pelicans at night may be enhanced by seizing prey close to the sea surface using a sit-and-wait strategy.

  20. Fasciola hepatica Infection in an Indigenous Community of the Peruvian Jungle.

    PubMed

    Cabada, Miguel M; Castellanos-Gonzalez, Alejandro; Lopez, Martha; Caravedo, María Alejandra; Arque, Eulogia; White, Arthur Clinton

    2016-06-01

    Fasciola hepatica is a zoonotic infection with a worldwide distribution. Autochthonous cases have not been reported in the Amazon region of Peru. Operculated eggs resembling F. hepatica were identified in the stools of five out of 215 subjects in a remote indigenous community of the Peruvian jungle. Polymerase chain reaction targeting Fasciola hepatica cytochrome oxidase subunit 1 (COI) gene and sequencing of the products confirmed Fasciola infection. © The American Society of Tropical Medicine and Hygiene.

  1. Patterns of GPS Tracks Suggest Nocturnal Foraging by Incubating Peruvian Pelicans (Pelecanus thagus)

    PubMed Central

    Zavalaga, Carlos B.; Dell'Omo, Giacomo; Becciu, Paolo; Yoda, Ken

    2011-01-01

    Most seabirds are diurnal foragers, but some species may also feed at night. In Peruvian pelicans (Pelecanus thagus), the evidence for nocturnal foraging is sparse and anecdotal. We used GPS-dataloggers on five incubating Peruvian pelicans from Isla Lobos de Tierra, Perú, to examine their nocturnality, foraging movements and activities patterns at sea. All instrumented pelicans undertook nocturnal trips during a 5–7 day tracking period. Eighty-seven percent of these trips (n = 13) were strictly nocturnal, whereas the remaining occurred during the day and night. Most birds departed from the island after sunset and returned a few hours after sunrise. Birds traveled south of the island for single-day trips at a maximum range of 82.8 km. Overall, 22% of the tracking period was spent at sea, whereas the remaining time was spent on the island. In the intermediate section of the trip (between inbound and outbound commutes), birds spent 77% of the trip time in floating bouts interspersed by short flying bouts, the former being on average three times longer than the latter. Taken together, the high sinuosity of the bird's tracks during floating bouts, the exclusively nocturnal trips of most individuals, and the fact that all birds returned to the island within a few hours after sunrise suggest that pelicans were actively feeding at night. The nocturnal foraging strategy of Peruvian pelicans may reduce food competition with the sympatric and strictly diurnal Guanay cormorants (Phalacrocorax bougainvillii), Peruvian boobies (Sula variegata) and Blue-footed boobies (S. nebouxii), which were present on the island in large numbers. Likewise, plankton bioluminescence might be used by pelicans as indirect cues to locate anchovies during their upward migration at night. The foraging success of pelicans at night may be enhanced by seizing prey close to the sea surface using a sit-and-wait strategy. PMID:21647444

  2. Size increment of jumbo flying squid Dosidicus gigas mature females in Peruvian waters, 1989-2004

    NASA Astrophysics Data System (ADS)

    Argüelles, Juan; Tafur, Ricardo; Taipe, Anatolio; Villegas, Piero; Keyl, Friedeman; Dominguez, Noel; Salazar, Martín

    2008-10-01

    Changes in population structure of the jumbo flying squid Dosidicus gigas in Peruvian waters were studied based on size-at-maturity from 1989 to 2004. From 1989 to 1999, mature squid belonging to the medium-sized group prevailed, but from 2001 on, mature squids were larger. This change is not related to the changes in sea surface temperature and we hypothesized that it was caused by the population increase of mesopelagic fishes as prey.

  3. Water contamination from oil extraction activities in Northern Peruvian Amazonian rivers.

    PubMed

    Yusta-García, Raúl; Orta-Martínez, Martí; Mayor, Pedro; González-Crespo, Carlos; Rosell-Melé, Antoni

    2017-06-01

    Oil extraction activities in the Northern Peruvian Amazon have generated a long-standing socio-environmental conflict between oil companies, governmental authorities and indigenous communities, partly derived from the discharge of produced waters containing high amounts of heavy metals and hydrocarbons. To assess the impact of produced waters discharges we conducted a meta-analysis of 2951 river water and 652 produced water chemical analyses from governmental institutions and oil companies reports, collected in four Amazonian river basins (Marañon, Tigre, Corrientes and Pastaza) and their tributaries. Produced water discharges had much higher concentrations of chloride, barium, cadmium and lead than are typically found in fresh waters, resulting in the widespread contamination of the natural water courses. A significant number of water samples had levels of cadmium, barium, hexavalent chromium and lead that did not meet Peruvian and international water standards. Our study shows that spillage of produced water in Peruvian Amazon rivers placed at risk indigenous population and wildlife during several decades. Furthermore, the impact of such activities in the headwaters of the Amazon extended well beyond the boundaries of oil concessions and national borders, which should be taken into consideration when evaluating large scale anthropogenic impacts in the Amazon. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Homogeneous temperature and precipitation series for a Peruvian High Andes regions from 1965 to 2009

    NASA Astrophysics Data System (ADS)

    Acuña, D.; Serpa Lopez, B.; Silvestre, E.; Konzelmann, Th.; Rohrer, M.; Schwarb, M.; Salzmann, N.

    2010-09-01

    As a basis of a joint Swiss-Peruvian effort focused on water resources, food security and disaster preparedness (Peruvian Climate Adaptation Project, PACC) clean and homogenized meteorological datasets have been elaborated for the Cusco and Apurimac Regions in the Central Andes. Operational and historical data series of more than 100 stations of the Peruvian Meteorological and Hydrological Service (SENAMHI) were available as a data base. Additionally, meteorological data provided by the National Climatic Data Centre (NCDC) or the Meteorological Aerodrome Records (METAR), have been considered. In contrast to many European countries, where most conventional sensors have been replaced by automated sensors during the last decades, instrumentation of climatological stations remained unchanged in Peru. Station records and station history of the Cusco-Apurimac-region are partially fragmentary or lost, mainly because of armed conflicts, particularly in the 1980ies. Moreover, many stations do observe precipitation as only variable. As a consequence, it was only possible so far to elaborate four complete homogenized air temperature series (Curahuasi 2763m a.s.l., Granja Kcayra-Cusco 3219m, Sicuani, 3574m and La Angostura, 4150m) since 1965. For precipitation a larger number of stations was available for elaboration, which is important because of the small scaled characteristics of the mostly convective type precipitation events in these regions. Based on these homogenized series, linear and gaussian low pass filtered trends have been calculated for all series of precipitation and air temperature records.

  5. Substance use and sexual risk behaviors among Peruvian MSM social media users

    PubMed Central

    Young, Sean D.; Nianogo, Roch A.; Chiu, ChingChe J.; Menacho, Lucho; Galea, Jerome

    2015-01-01

    Peru is experiencing a concentrated HIV epidemic among men who have sex with men (MSM). Substance use (alcohol and drug use) has been found to be associated with HIV-related sexual risk behaviors. A recent surge in the number of social media users in Peru has enabled these technologies to be potential tools for reaching HIV at-risk individuals. This study sought to assess the relationship between substance use and sexual risk behaviors among Peruvian MSM who use social media. A total of 556 Peruvian MSM Facebook users (ages 18–59) were recruited to complete a 92-item survey on demographics, sexual risk behaviors, and substance use. We performed a logistic regression of various sexual risk behaviors (e.g. unprotected sex, casual sex) on substance abuse, including alcohol, adjusting for potential covariates. Drinking more than five alcoholic drinks a day in the past three months was associated with an increased odds of having unprotected sex (vaginal and anal) (aOR: 1.52; 95%CL: 1.01, 2.28), casual sex (1.75; 1.17, 2.62) and sex with unknown persons (1.82; 1.23, 2.71). Drug use was not significantly associated with sexual risk behaviors. Among Peruvian MSM social media users, findings suggest that alcohol use was associated with increased HIV-related sexual risk behaviors. PMID:26324405

  6. A millennium of metallurgy recorded by lake sediments from Morococha, Peruvian Andes.

    PubMed

    Cooke, Colin A; Abbott, Mark B; Wolfe, Alexander P; Kittleson, John L

    2007-05-15

    To date, information concerning pre-Colonial metallurgy in South America has largely been limited to the archaeological record of artifacts. Here, we reconstruct a millennium of smelting activity in the Peruvian Andes using the lake-sediment stratigraphy of atmospherically derived metals (Pb, Zn, Cu, Ag, Sb, Bi, and Ti) and lead isotopic ratios (206Pb/ 207Pb) associated with smelting from the Morococha mining region in the central Peruvian Andes. The earliest evidence for metallurgy occurs ca. 1000 A.D., coinciding with the fall of the Wari Empire and decentralization of local populations. Smelting during this interval appears to have been aimed at copper and copper alloys, because of large increases in Zn and Cu relative to Pb. A subsequent switch to silver metallurgy under Inca control (ca. 1450 to conquest, 1533 A.D.) is indicated by increases in Pb, Sb, and Bi, a conclusion supported by further increases of these metals during Colonial mining, which targeted silver extraction. Rapid development of the central Andes during the 20th century raised metal burdens by an order of magnitude above previous levels. Our results represent the first evidence for pre-Colonial smelting in the central Peruvian Andes, and corroborate the sensitivity of lake sediments to pre-Colonial metallurgical activity suggested by earlier findings from Bolivia.

  7. Tracing the genomic ancestry of Peruvians reveals a major legacy of pre-Columbian ancestors.

    PubMed

    Sandoval, Jose R; Salazar-Granara, Alberto; Acosta, Oscar; Castillo-Herrera, Wilder; Fujita, Ricardo; Pena, Sergio D J; Santos, Fabricio R

    2013-09-01

    In order to investigate the underlying genetic structure and genomic ancestry proportions of Peruvian subpopulations, we analyzed 551 human samples of 25 localities from the Andean, Amazonian, and Coastal regions of Peru with a set of 40 ancestry informative insertion-deletion polymorphisms. Using genotypes of reference populations from different continents for comparison, our analysis indicated that populations from all 25 Peruvian locations had predominantly Amerindian genetic ancestry. Among populations from the Titicaca Lake islands of Taquile, Amantani, Anapia, and Uros, and the Yanque locality from the southern Peruvian Andes, there was no significant proportion of non-autochthonous genomes, indicating that their genetic background is effectively derived from the first settlers of South America. However, the Andean populations from San Marcos, Cajamarca, Characato and Chogo, and coastal populations from Lambayeque and Lima displayed a low but significant European ancestry proportion. Furthermore, Amazonian localities of Pucallpa, Lamas, Chachapoyas, and Andean localities of Ayacucho and Huancayo displayed intermediate levels of non-autochthonous ancestry, mostly from Europe. These results are in close agreement with the documented history of post-Columbian immigrations in Peru and with several reports suggesting a larger effective size of indigenous inhabitants during the formation of the current country's population.

  8. Substance use and sexual risk behaviors among Peruvian MSM social media users.

    PubMed

    Young, Sean D; Nianogo, Roch A; Chiu, ChingChe J; Menacho, Lucho; Galea, Jerome

    2016-01-01

    Peru is experiencing a concentrated HIV epidemic among men who have sex with men (MSM). Substance use (alcohol and drug use) has been found to be associated with HIV-related sexual risk behaviors. A recent surge in the number of social media users in Peru has enabled these technologies to be potential tools for reaching HIV at-risk individuals. This study sought to assess the relationship between substance use and sexual risk behaviors among Peruvian MSM who use social media. A total of 556 Peruvian MSM Facebook users (ages 18-59) were recruited to complete a 92-item survey on demographics, sexual risk behaviors, and substance use. We performed a logistic regression of various sexual risk behaviors (e.g., unprotected sex, casual sex) on substance abuse, including alcohol, adjusting for potential covariates. Drinking more than five alcoholic drinks a day in the past three months was associated with an increased odds of having unprotected sex (vaginal and anal) (aOR: 1.52; 95% CL: 1.01, 2.28), casual sex (1.75; 1.17, 2.62), and sex with unknown persons (1.82; 1.23, 2.71). Drug use was not significantly associated with sexual risk behaviors. Among Peruvian MSM social media users, findings suggest that alcohol use was associated with increased HIV-related sexual risk behaviors.

  9. Nitrogen fixation in sediments along a depth transect through the Peruvian oxygen minimum zone

    NASA Astrophysics Data System (ADS)

    Gier, Jessica; Sommer, Stefan; Löscher, Carolin R.; Dale, Andrew W.; Schmitz, Ruth A.; Treude, Tina

    2016-07-01

    The potential coupling of nitrogen (N2) fixation and sulfate reduction (SR) was explored in sediments of the Peruvian oxygen minimum zone (OMZ). Sediment samples were retrieved by a multiple corer at six stations along a depth transect (70-1025 m water depth) at 12° S, covering anoxic and hypoxic bottom water conditions. Benthic N2 fixation, determined by the acetylene reduction assay, was detected at all sites, with highest rates between 70 and 253 m and lower rates at greater depth. SR rates decreased with increasing water depth. N2 fixation and SR overlapped in sediments, suggesting a potential coupling of both processes. However, a weak positive correlation of their activity distribution was detected by principle component analysis. A potential link between N2 fixation and sulfate-reducing bacteria was indicated by the molecular analysis of nifH genes. Detected nifH sequences clustered with the sulfate-reducing bacteria Desulfonema limicola at the 253 m station. However, nifH sequences of other stations clustered with uncultured organisms, Gammaproteobacteria, and Firmicutes (Clostridia) rather than with known sulfate reducers. The principle component analysis revealed that benthic N2 fixation in the Peruvian OMZ is controlled by organic matter (positive) and free sulfide (negative). No correlation was found between N2 fixation and ammonium concentrations (even at levels > 2022 µM). N2 fixation rates in the Peruvian OMZ sediments were in the same range as those measured in other organic-rich sediments.

  10. Stress field evolution above the Peruvian flat-slab (Cordillera Blanca, northern Peru)

    NASA Astrophysics Data System (ADS)

    Margirier, A.; Audin, L.; Robert, X.; Pêcher, A.; Schwartz, S.

    2017-08-01

    In subduction settings, the tectonic regime of the overriding plate is closely related to the geometry of the subducting plate. Flat-slab segments are supposed to increase coupling at the plate interface in the Andes, resulting in an increase and eastward migration of the shortening in the overriding plate. Above the Peruvian flat-slab, a 200 km-long normal fault trend parallel to the range and delimits the western flank of the Cordillera Blanca. In a context of flat subduction, expected to produce shortening, the presence of the Cordillera Blanca normal fault (CBNF) is surprising. We performed a systematic inversion of striated fault planes in the Cordillera Blanca region to better characterize the stress field above the Peruvian flat-slab. It evidences the succession of different tectonic regimes. NE-SW extension is predominant in most of the sites indicating a regional extension. We suggest that the Peruvian flat-slab trigger extension in the Western Cordillera while the shortening migrated eastward. Finally, we propose that flat-slab segments do not increase the coupling at the trench neither the shortening in the overriding plate but only favor shortening migration backward. However, the stress field of the overriding plate arises from the evolution of plate interface properties through time due to bathymetric anomaly migration.

  11. Social Well-Being Among Colombian and Peruvian Immigrants in Northern Chile.

    PubMed

    Urzúa Morales, Alfonso; Delgado-Valencia, Eric; Rojas-Ballesteros, Mariela; Caqueo-Urízar, Alejandra

    2016-04-02

    In recent years, northern Chile has received a large number of immigrants attracted mainly by mining and related services. The last population census revealed that 70.5 % of foreigners in Chile came from South America, and were mainly Peruvians (30.5 %), Argentines (16.8 %), and Colombians (8.1 %). The aim of this cross-sectional study is to describe the social well-being levels reported by Colombian and Peruvian immigrants in northern Chile, as well as their connection to socio-demographic and relational factors. The Spanish version of the Scale of Social Well-being (Keyes in Soc Psychol Q 61:121-140, 1998) was administered to 431 men and women over 18 years old, with a minimum residence of 6 months in the city of Antofagasta. The highest-rated aspect was Social Contribution, and the lowest-rated aspect was Social Acceptance. The relational variables that show statistically significant differences in both populations relate to who the subject lives with, the degree of contact that the subject has with people from Chile, and the subject's relationship status. There are no differences that indicate a higher level of social well-being in one population more than the other; however, it appears that the Peruvian population has a greater perception of Social Coherence, while Colombians show a greater perception of Social Contribution.

  12. [Knowledge, attitudes and practices ABOUT HIV/AIDS in peruvian women].

    PubMed

    Pernaz-Linsuy, Guillermo; Cárcamo-Cavagnaro, César

    2015-10-01

    To determine the level of knowledge, proper attitudes and safe sex practices regarding the Human Immunodeficiency Virus (HIV) infection in Peruvian women ages 15 to 49 years. We used the results of the Continuous 2004-2007 Peruvian Demographic and Health survey (DHS). The dependent variable comprised the level of knowledge and attitudes regarding the disease and safe sexual practices. Descriptive statistical analysis and logistic regression was performed to find association between variables. A good level of knowledge about sexually transmitted infection (including HIV infection) was found in 47.8% of women from the population surveyed; 50.7% showed proper attitudes in relation to the disease and the people affected by it, while safe sexual practices were observed in 48.8% of the persons surveyed. Higher educational level, high index of socio-economic welfare, residence in the capital city during childhood, working as professional, technical, business women or clerical position; and frequent media access, were related to greater knowledge, good attitudes and safe practices. The level of knowledge, attitudes and practices shown by 15 to 49 year old Peruvian women regarding sexually transmitted infections is not adequate.

  13. Toxoplasma gondii and Neospora caninum seroprevalences in domestic South American camelids of the Peruvian Andes.

    PubMed

    Chávez-Velásquez, Amanda; Aguado-Martínez, Adriana; Ortega-Mora, Luis M; Casas-Astos, Eva; Serrano-Martínez, Enrique; Casas-Velásquez, Gina; Ruiz-Santa-Quiteria, Jose A; Alvarez-García, Gema

    2014-10-01

    The objective of this study was to investigate the presence of Toxoplasma gondii- and Neospora caninum-specific antibodies in domestic South American camelids (SAC) (llamas and alpacas) from the Peruvian Andes through a cross-sectional study. A wide panel of serum samples collected from 1,845 llamas and 2,874 alpacas from the two main SAC production areas of Peru was selected. Immunofluorescence antibody technique was employed to detect and titrate specific anti-T. gondii and anti-N. caninum immunoglobulins G in serum samples. The association between T. gondii and N. caninum seroprevalence and the geographical origin (Central and South Peruvian Andes) was evaluated. Anti-T. gondii antibodies were found in 460 (24.9 %) llamas and 706 (24.6 %) alpacas, whereas anti-N. caninum antibodies were detected in 153 (8.3 %) llamas and 425 (14.8 %) alpacas. Toxoplasma gondii infection was strongly associated with the South Peruvian Andes where moderate climate conditions, larger human population, compared to the Central region, and the presence of wildlife definitive hosts could favor horizontal transmission to SAC. In contrast, N. caninum infection was not associated with the geographical region. These results indicate that T. gondii and N. caninum infections are highly and moderately widespread, respectively, in both species of domestic SAC studied in the sampled areas and appropriate control measures should be undertaken to reduce the prevalence of both parasitic infections.

  14. [Cost-utility of the vaccine against the Human Papiloma Virus in Peruvian women].

    PubMed

    Gutiérrez-Aguado, Alfonso

    2011-01-01

    To estimate the cost-utility of the vaccine against the Human Papiloma Virus (HPV) in peruvian women after the application of the vaccine at 10 years of age. A cost-utility analysis was performed using the Markov´s hidden model in a hypothetical cohort of peruvian women, based on the information on epidemiological parameters, costs associated to uterine cervical cancer (UCC) and the efficacy and costs of the vaccine against the HPV. The vaccination costs were estimated from the Peruvian Ministry of Health perspective and were compared against the quality-adjusted life years (QALYs), using a discount rate of 5%. The annual cost of the vaccination was USD 16,861,490, for the Papanicoau screening it was USD 3,060,793 and the costs associated to the UCC were USD 15,580,000. The incremental cost utility ratio (ICUR) was 6,775 USD/QALY. Vaccination against HPV can be cost-utility compared to not vaccinating.

  15. Growth and body composition of Peruvian infants in a periurban setting.

    PubMed

    Iannotti, Lora L; Zavaleta, Nelly; León, Zulema; Caulfield, Laura E

    2009-09-01

    Previous growth studies of Peruvian children have featured high stunting rates and limited information about body composition. We aimed to characterize anthropometric measures of Peruvian infants 0 to 12 months of age in relation to the international growth references and biological, environmental, and socioeconomic factors. Infants (n = 232) were followed longitudinally from birth through 12 months of age from a prenatal zinc supplementation trial conducted in Lima, Peru, between 1995 and 1997. Anthropometric measures of growth and body composition were obtained at enrollment from mothers and monthly through 1 year of age from infants. Weekly morbidity and dietary intake surveillance was carried out during the second half of infancy. The prevalence rates of stunting, underweight, and wasting did not exceed 4% based on the World Health Organization growth references. Infants of mothers from high-altitude regions had larger chest circumference (p = .006) and greater length (p = .06) by 12 months. Significant predictors of growth and body composition throughout infancy were age, sex, anthropometric measurements at birth, breastfeeding, maternal anthropometric measurements, primiparity, prevalence of diarrhea among children, and the altitude of the region of maternal origin. No associations were found for maternal education, asset ownership, or sanitation and hygiene factors. Peruvian infants in this urban setting had lower rates of stunting than expected. Proximal and familial conditions influenced growth throughout infancy.

  16. Centile curves and reference values for height, body mass, body mass index and waist circumference of Peruvian children and adolescents.

    PubMed

    Bustamante, Alcibíades; Freitas, Duarte; Pan, Huiqi; Katzmarzyk, Peter T; Maia, José

    2015-03-09

    This study aimed to provide height, body mass, BMI and waist circumference (WC) growth centile charts for school-children, aged 4-17 years, from central Peru, and to compare Peruvian data with North-American and Argentinean references. The sample consisted of 8753 children and adolescents (4130 boys and 4623 girls) aged 4 to 17 years, from four Peruvian cities: Barranco, La Merced, San Ramón and Junín. Height, body mass and WC were measured according to standardized techniques. Centile curves for height, body mass, BMI and WC were obtained separately for boys and girls using the LMS method. Student t-tests were used to compare mean values. Overall boys have higher median heights than girls, and the 50th percentile for body mass increases curvilinearly from 4 years of age onwards. In boys, the BMI and WC 50th percentiles increase linearly and in girls, the increase presents a curvilinear pattern. Peruvian children are shorter, lighter and have higher BMI than their counterparts in the U.S. and Argentina; in contrast, age and sex-specific WC values are lower. Height, body mass and WC of Peruvian children increased with age and variability was higher at older ages. The growth patterns for height, body mass, BMI and WC among Peruvian children were similar to those observed in North-American and Argentinean peers.

  17. Centile Curves and Reference Values for Height, Body Mass, Body Mass Index and Waist Circumference of Peruvian Children and Adolescents

    PubMed Central

    Bustamante, Alcibíades; Freitas, Duarte; Pan, Huiqi; Katzmarzyk, Peter T.; Maia, José

    2015-01-01

    This study aimed to provide height, body mass, BMI and waist circumference (WC) growth centile charts for school-children, aged 4–17 years, from central Peru, and to compare Peruvian data with North-American and Argentinean references. The sample consisted of 8753 children and adolescents (4130 boys and 4623 girls) aged 4 to 17 years, from four Peruvian cities: Barranco, La Merced, San Ramón and Junín. Height, body mass and WC were measured according to standardized techniques. Centile curves for height, body mass, BMI and WC were obtained separately for boys and girls using the LMS method. Student t-tests were used to compare mean values. Overall boys have higher median heights than girls, and the 50th percentile for body mass increases curvilinearly from 4 years of age onwards. In boys, the BMI and WC 50th percentiles increase linearly and in girls, the increase presents a curvilinear pattern. Peruvian children are shorter, lighter and have higher BMI than their counterparts in the U.S. and Argentina; in contrast, age and sex-specific WC values are lower. Height, body mass and WC of Peruvian children increased with age and variability was higher at older ages. The growth patterns for height, body mass, BMI and WC among Peruvian children were similar to those observed in North-American and Argentinean peers. PMID:25761169

  18. Some Key Issues in Intercultural Bilingual Education Teacher Training Programmes--as Seen from a Teacher Training Programme in the Peruvian Amazon Basin.

    ERIC Educational Resources Information Center

    Trapnell, Lucy A.

    2003-01-01

    Presents a critical reflection of the author's 14-year experience in the Teacher Training Program for Intercultural Bilingual Education in the Peruvian Amazon Basin, developed by a national Peruvian indigenous confederation and the Loreto state teacher training college. Focuses on ethical, political, and pedagogical challenges that intercultural…

  19. Some Key Issues in Intercultural Bilingual Education Teacher Training Programmes--as Seen from a Teacher Training Programme in the Peruvian Amazon Basin.

    ERIC Educational Resources Information Center

    Trapnell, Lucy A.

    2003-01-01

    Presents a critical reflection of the author's 14-year experience in the Teacher Training Program for Intercultural Bilingual Education in the Peruvian Amazon Basin, developed by a national Peruvian indigenous confederation and the Loreto state teacher training college. Focuses on ethical, political, and pedagogical challenges that intercultural…

  20. Peruvian Trench to Andean Thrust Front: Evidence for Coupling of the Peruvian Flat Slab to the Over-Riding South American Plate

    NASA Astrophysics Data System (ADS)

    Bishop, B.; Beck, S. L.; Zandt, G.; Scire, A. C.; Wagner, L. S.; Long, M. D.; Tavera, H.

    2014-12-01

    In central Peru the combination of an unusually shallow Wadati-Benioff zone and lack of arc volcanism are indicators of flat slab subduction and are associated with both the ongoing subduction of the Nazca Ridge and the prior subduction of the Inca Plateau. Data from the PULSE experiment has allowed us to better constrain the geometry of the southern half of the Peruvian flat slab through analysis of teleseismic receiver functions, Pn and Sn phases from regional intermediate (>100 km depth) and deep (>500 km depth) earthquakes at the margins of the flat slab region, and teleseismic tomgraphy. We observe a low velocity anomaly below the subducted portion of the Nazca Ridge in the teleseismic S-wave tomography. Utilizing both Pn and Sn phases from regional intermediate and deep earthquakes at the margins of the flat slab, we have found significant travel time delays for propagation paths passing through this anomaly, confirming the presence of this low velocity anomaly under the flat slab. This anomaly likely contributes to the buoyancy of this segment of the flat slab, increasing the coupling with the upper plate. Both the teleseismic tomographic and our receiver function results indicate that the southern segment of the Peruvian flat slab extends locally more than 100 km further inboard than previous estimates. As the shallow portion of the slab inboard of the subducting Nazca Ridge is largely aseismic, these new results help to better constrain the geometry of the Peruvian flat slab as it re-subducts back into the mantle. Between 10°S and 16°S the subducted oceanic crust along the inboard projection of the Nazca Ridge lies at a depth of 60 km to 70 km while subducted crust immediately north and south of the ridge projection lies at depths of 80 km to 90 km suggesting the slab is sinking north and south of the ridge. The unusually shallow depth of the slab along the ridge's projection may indicate that the subducted Nazca Plate is coupled to the South American

  1. Cryopreservation of Peruvian Paso horse spermatozoa: dimethylacetamide preserved an optimal sperm function compared to dimethyl sulfoxide, ethylene glycol and glycerol.

    PubMed

    Santiani, A; Evangelista-Vargas, S; Vargas, S; Gallo, S; Ruiz, L; Orozco, V; Rosemberg, M

    2017-08-01

    The objective was to evaluate the effect of different cryoprotectant agents in the cryopreservation of Peruvian Paso horse semen. Twenty semen samples were collected from five Peruvian Paso horse stallions. Each sample was divided into 12 parts to form the groups: dimethylacetamide (DMA), dimethyl sulfoxide (DMSO), ethylene glycol (EG) and glycerol (GLY), at 3%, 4% and 5%. Samples were frozen using a rate-controlled freezer. Sperm parameters evaluated were motility and viability/acrosomal status. After thawing, progressive motility in DMA group was higher (p < .05) than in DMSO, EG and GLY groups. Similarly, viable acrosome-intact spermatozoa were higher (p < .05) using DMA in comparison with DMSO. No differences were found when comparing concentrations for any of the cryoprotectant agents. In conclusion, DMA seems to be a good cryoprotectant agent for the cryopreservation of Peruvian Paso horse stallion semen. © 2016 Blackwell Verlag GmbH.

  2. Modelling multiple threats to water security in the Peruvian Amazon using the WaterWorld policy support system

    NASA Astrophysics Data System (ADS)

    van Soesbergen, A. J. J.; Mulligan, M.

    2014-01-01

    This paper describes the application of WaterWorld (www.policysupport.org/waterworld) to the Peruvian Amazon, an area that is increasingly under pressure from deforestation and water pollution as a result of population growth, rural-to-urban migration and oil and gas extraction, potentially impacting both water quantity and water quality. By applying single and combined plausible scenarios of climate change, deforestation around existing and planned roads, population growth and rural-urban migration, mining and oil and gas exploitation, we explore the potential combined impacts of these multiple changes on water resources in the Peruvian Amazon.

  3. Impact of HLA-DRB1 allele polymorphisms on control of HIV infection in a Peruvian MSM cohort.

    PubMed

    Oriol-Tordera, B; Llano, A; Ganoza, C; Cate, S; Hildebrand, W; Sanchez, J; Calle, M L; Brander, C; Olvera, A

    2017-10-01

    Associations between HLA class II polymorphisms and HIV control were assessed in a Peruvian MSM cohort. Among 233 treatment naïve HIV+ individuals, DRB1*13:02 was linked to elevated viral loads (P = .044) while DRB1*12:01 showed significantly lower viral set points (P = .015) and restricted a dominant T cell response to HIV Gag p24 (P = .038). The present work contributes to a better knowledge of the Peruvian immunogenetics and supports the important role of HLA class II restricted T cells in HIV control. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Psychometric Properties of the Pittsburgh Sleep Quality Index (PSQI) in a Cohort of Peruvian Pregnant Women

    PubMed Central

    Zhong, Qiu-Yue; Gelaye, Bizu; Sánchez, Sixto E.; Williams, Michelle A.

    2015-01-01

    Study Objectives: We sought to evaluate the construct validity and factor structure of the Spanish-language version of the Pittsburgh Sleep Quality Index (PSQI) among pregnant Peruvian women. Methods: A cohort of 642 women were interviewed at ≤ 16 weeks of gestation. During interview, we ascertained information about lifestyles, demographics, sleep characteristics, and mood symptoms. Stress induced sleep disturbance, depressive symptoms, and anxiety symptoms were evaluated using the Ford Insomnia Response to Stress Test (FIRST), Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7) assessment scales, respectively. Consistency indices, exploratory and confirmatory factor analyses, correlations, and logistic regressions were used. Results: Both exploratory and confirmatory factor analyses indicated a three-factor solution: sleep quality, sleep efficiency, and sleep medication. We observed significantly positive correlations of the PSQI with the FIRST (0.42), the PHQ-9 (0.49), and the GAD-7 (0.46). Poor sleepers (PSQI global score > 5) had significantly increased odds of experiencing stress-induced sleep disturbance (odds ratio, OR = 3.57; 95% CI: 2.40, 5.31), depression (OR = 5.48; 95% CI: 3.58, 8.37), and generalized anxiety disorder (OR = 4.57; 95% CI: 3.08, 6.76). Conclusions: The Spanish-language version of the PSQI instrument was found to have good construct validity among pregnant Peruvian women. Consistent with some other studies, the PSQI was found to have a three-factor structure. Further assessment and validation studies are needed to determine whether the three, factor-specific scoring of the PSQI is favored over the PSQI global score in diverse populations. Citation: Zhong QY, Gelaye B, Sánchez SE, Williams MA. Psychometric properties of the Pittsburgh Sleep Quality Index (PSQI) in a cohort of Peruvian pregnant women. J Clin Sleep Med 2015;11(8):869–877. PMID:25845902

  5. An Analysis of and Recommendations for the Peruvian Blood Collection and Transfusion System

    PubMed Central

    George, Paul E; Vidal, Julio; Garcia, Patricia J

    2016-01-01

    Background Peru experienced a crisis in its blood collection and supply system in the mid-2000s, as contaminated blood led to several transfusion-transmitted infections (TTI), occurring in the backdrop of extremely low voluntary donation rates and a national blood supply shortage. Thus, the Peruvian Ministry of Health (MINSA) implemented a national investigation on the safety and quality of the Peruvian blood collection/transfusion network. Methods Every Peruvian blood bank was evaluated by MINSA from 2007–2008. These evaluations consisted of an update of the national registry of blood banks and visits to each blood bank from MINSA oversight teams. Information was collected on the condition of the blood bank personnel, equipment, supplies, and practices. Further, previously-collected blood at each blood bank was randomly selected and screened for TTI-causing pathogens. Results Uncovered in this investigation was a fragmented, under-equipped, and poorly-staffed blood collection and transfusion network, consisting of 241 independent blood banks and resulting in suboptimal allocation of resources. Further, blood with evidence of TTI-causing pathogens (including Hepatitis B, Hepatitis C, and syphilis) and set for transfusion was discovered at three separate blood banks as part of the random screening process. Conclusion Using the successful reorganizations of national blood supply systems in other Latin American countries as examples, Peru would be well-served to form large, high-volume, regional blood collection and transfusion centers, responsible for blood collection and screening for the entire country. The small, separate blood banks would then be transformed into a network of blood transfusion centers, not responsible for blood collection. This reorganization would allow Peru to better utilize its resources, standardize the blood collection and transfusion process, and increase voluntary donation, resulting in a safer, more abundant national blood product. PMID

  6. New species and geographical records of dactylogyrids (Monogenea) of catfish (Siluriformes) from the Peruvian Amazonia.

    PubMed

    Mendoza-Palmero, Carlos A; Scholz, Tomáš; Mendoza-Franco, Edgar F; Kuchta, Roman

    2012-06-01

    Three new species of gill monogeneans (Dactylogyridae: Ancyrocephalinae) are described from siluriform catfish from Iquitos, Peru: Demidospermus mortenthaleri n. sp. from Brachyplatystoma juruense (Boulenger), Demidospermus brevicirrus n. sp. from Pimelodus sp., and Aphanoblastella aurorae n. sp. from Goeldiella eques (Müller & Troschel). Demidospermus mortenthaleri is characterized by a male copulatory organ (MCO) with a small loop at its middle portion; 2 types of hooks, of which pairs 5 and 6 are longer than the remaining hooks; a proximal subunit round and highly depressed thumb; and a sclerotized vagina with a round pad at the vaginal aperture. Demidospermus brevicirrus is distinguished from other congeners by the presence of a short, straight, and robust MCO and boot-shaped accessory piece with a hooked projection directed posteriorly. Aphanoblastella aurorae is the only species of the genus that possesses an arrow-shaped sclerotized vagina and a medial process on the dorsal bar. Another 6 dactylogyrids described previously are recorded for the first time from the Peruvian Amazonia: Cosmetocleithrum bulbocirrus Kritsky, Thatcher and Boeger, 1986 ; Vancleaveus fungulus Kritsky, Thatcher and Boeger, 1986 ; V. janauacaensis Kritsky, Thatcher and Boeger, 1986 ; V. platyrhynchi Kritsky, Thatcher and Boeger, 1986 ; Unilatus unilatus Mizelle and Kritsky, 1967 ; and U. brittani Mizelle, Kritsky and Crane, 1968 . Based on observations of specimens collected in the Peruvian Amazonia, new morphological data for these species are provided. Comparison of new specimens of U. unilatus and U. brittani with those of Unilatus brevispinus Suriano, 1985 and Unilatus longispinus Suriano, 1985 , both originally described from Brazil, has shown that they are conspecific. Therefore, the latter species were synonymized with U. unilatus and U. brittani , respectively. In addition, 56 undescribed monogeneans found in catfish from the Peruvian Amazonia, some of them probably belonging

  7. Social and economic causes of deforestation in the Peruvian Amazon basin: Natives and colonists. Working paper

    SciTech Connect

    Garland, E.B.

    1991-03-01

    The people in the Peruvian Amazon directly engaged in agriculture are the leading cause of deforestation; and can be divided into two groups, colonists and indigenous groups. The factors affecting the rate at which each group causes deforestation differ. The paper explores these differences in Peru's Upper Huallaga Valley (the principal coca producing region in the world), focusing on the interrelationships between land availability, land tenure laws, and market forces on one hand, and agricultural intensification and deforestation on the other. The study concludes that the technological decisions of the two groups are guided by diverse sets of socioeconomic factors.

  8. [Hantavirus pulmonary syndrome (Rio Mamore virus) in the Peruvian Amazon region].

    PubMed

    Casapía, Martín; Mamani, Enrique; García, María P; Miraval, María L; Valencia, Pedro; Quino, Alberto H; Alvarez, Carlos; Donaires, Luis F

    2012-01-01

    Hantavirus infection is a viral zoonotic infection borne by rodents which most letal form clinical is the Hantavirus Pulmonary Syndrome (SPH, Spanish abbreviation). The Mamore River variant originates in South America and was found in rodents without any association to human diseases. Two cases of SPH were identified in the Peruvian Amazon region in November 2011. In both cases, a molecular diagnostic testing was conducted by the Instituto Nacional de Salud from Peru. A phylogenetic analysis of a viral genome fragment and a histopathological evaluation were conducted. Both patients developed adult respiratory distress syndrome and refractory shock. A patient died and another one recovered 12 days later.

  9. Patterns in the spatial distribution of Peruvian anchovy ( Engraulis ringens) revealed by spatially explicit fishing data

    NASA Astrophysics Data System (ADS)

    Bertrand, Sophie; Díaz, Erich; Lengaigne, Matthieu

    2008-10-01

    Peruvian anchovy ( Engraulis ringens) stock abundance is tightly driven by the high and unpredictable variability of the Humboldt Current Ecosystem. Management of the fishery therefore cannot rely on mid- or long-term management policy alone but needs to be adaptive at relatively short time scales. Regular acoustic surveys are performed on the stock at intervals of 2 to 4 times a year, but there is a need for more time continuous monitoring indicators to ensure that management can respond at suitable time scales. Existing literature suggests that spatially explicit data on the location of fishing activities could be used as a proxy for target stock distribution. Spatially explicit commercial fishing data could therefore guide adaptive management decisions at shorter time scales than is possible through scientific stock surveys. In this study we therefore aim to (1) estimate the position of fishing operations for the entire fleet of Peruvian anchovy purse-seiners using the Peruvian satellite vessel monitoring system (VMS), and (2) quantify the extent to which the distribution of purse-seine sets describes anchovy distribution. To estimate fishing set positions from vessel tracks derived from VMS data we developed a methodology based on artificial neural networks (ANN) trained on a sample of fishing trips with known fishing set positions (exact fishing positions are known for approximately 1.5% of the fleet from an at-sea observer program). The ANN correctly identified 83% of the real fishing sets and largely outperformed comparative linear models. This network is then used to forecast fishing operations for those trips where no observers were onboard. To quantify the extent to which fishing set distribution was correlated to stock distribution we compared three metrics describing features of the distributions (the mean distance to the coast, the total area of distribution, and a clustering index) for concomitant acoustic survey observations and fishing set positions

  10. Native dialect influences second-language vowel perception: Peruvian versus Iberian Spanish learners of Dutch.

    PubMed

    Escudero, Paola; Williams, Daniel

    2012-05-01

    Peruvian Spanish (PS) and Iberian Spanish (IS) learners were tested on their ability to categorically discriminate and identify Dutch vowels. It was predicted that the acoustic differences between the vowel productions of the two dialects, which compare differently to Dutch vowels, would manifest in differential L2 perception for listeners of these two dialects. The results show that although PS learners had higher general L2 proficiency, IS learners were more accurate at discriminating all five contrasts and at identifying six of the L2 Dutch vowels. These findings confirm that acoustic differences in native vowel production lead to differential L2 vowel perception.

  11. Histopathological Study of a Mummified Eye and Optic Nerve from a Strangled Peruvian Mummy.

    PubMed

    Esteban, Jordi; Cases-Mérida, Sandra; Tortosa, Montserrat; Marzal, Berta; Fernández, Arabel; Gálvez, Cesar; Franco, Regulo; Fernández, Pedro Luis

    2015-01-01

    We present the histopathological findings of a naturally mummified eye from the Peruvian Lambayeque culture (900-1,200 AD), in which rehydration, light microscopy, and scanning electron microscopy allowed a detailed analysis of several eye tissues including the eyelids, sclera, and optic nerve, the latter showing evidence of hemorrhage likely related to the documented strangulation as the cause of death. We conclude that histopathological analysis of rehydrated mummified tissues can provide valuable information from fragile eye structures including the optic nerve, and these findings can be useful from a forensic point of view.

  12. Cryptococcus gattii meningoencephalitis in an HIV-negative patient from the Peruvian Andes.

    PubMed

    Gutierrez, Ericson L; Valqui, Willi; Vilchez, Luis; Evangelista, Lourdes; Crispin, Sarita; Tello, Mercedes; Navincopa, Marcos; Béjar, Vilma; Gonzáles, José; Ortega-Loayza, Alex G

    2010-01-01

    We report a case of an immunocompetent Peruvian patient from the Andes with a one-month history of meningoencephalitis. Cryptococcus gattii was identified from a cerebrospinal fluid culture through assimilation of D-proline and D-tryptophan as the single nitrogen source. Initially, the patient received intravenous antifungal therapy with amphotericin B. The patient was discharged 29 days after hospitalization and continued with oral fluconazole treatment for ten weeks. During this period, the patient showed clinical improvement with slight right-side residual weakness. Through this case report, we confirm the existence of this microorganism as an infectious agent in Peru.

  13. Diatoms from the Colombian and Peruvian Amazon: the Genera Encyonema, Encyonopsis and Gomphonema (Cymbellales: Bacillariophyceae).

    PubMed

    Vouilloud, Amelia A; Sala, Silvia E; Avellaneda, Marcela Núñez; Duque, Santiago R

    2010-03-01

    The diatom flora of the Colombian and Peruvian Amazon is far less studied than the flora of the Brazilian sector of the basin. Here we present results related to the genera Encyonema, Encyonopsis and Gomphonema. Plankton and periphyton samples were collected in lotic and lentic waterbodies from the Amazonian-Andean region, the Amazon River, Japurá River and Porvenir River basins during 1993, 1994, 2001 and 2003. At each sampling station pH, temperature, water transparency and conductivity were registered. Samples were analyzed with phase contrast microscope (LM) and scanning electron microscope (SEM). Ten taxa are new records for the area; Encyonema for the Peruvian and Colombian Amazon and Encyonopsis for the Colombian Sector. Encyonema neogracile var. tenuipunctatum, E. vulgare, Encyonopsis frequentis, Gomphonema augur var. sphaerophorum and G. contraturris are recorded for the first time in Colombia; Encyonema venezolanum and G. neoapiculatum in Colombia and Peru and the latter also for Amazonia. E. angustecapitatum was mentioned in Colombia before at a pond located at 3000 m asl. We describe a new species from Porvenir River, Amazonas, Colombia: Encyonema amazonianum.

  14. Mesozoic arc magmatism along the southern Peruvian margin during Gondwana breakup and dispersal

    NASA Astrophysics Data System (ADS)

    Boekhout, Flora; Spikings, Richard; Sempere, Thierry; Chiaradia, Massimo; Ulianov, Alexey; Schaltegger, Urs

    2012-08-01

    A high-resolution U-Pb zircon geochronological study of plutonic units along the south Peruvian margin between 17° and 18°S allows the integration of the geochemical, geodynamic and tectonic evolution of this part of the Andean margin. This study focuses on the composite Jurassic-early Cretaceous Ilo Batholith that was emplaced along the southern Peruvian coast during two episodes of intrusive magmatism; a first period between 173 and 152 Ma (with a peak in magmatic activity between roughly 168 and 162 Ma) and a second period between 110 and 106 Ma. Emplacement of the Jurassic part of the composite Ilo Batholith shortly post-dated the accumulation of the volcanosedimentary succession it intruded (Chocolate formation), which allows to estimate a subsidence rate for this unit of ~ 3.5 km/Ma. The emplacement of the main peak of Jurassic plutonism of the Ilo Batholith was also closely coeval with widespread and repeated slumping (during deposition of the Cachíos Formation) in the back-arc region, suggesting a common causal link between these phenomena, which is discussed in the context of an observed 100 km trenchward arc migration at ~ 175 Ma, and the relation with extensional tectonics that prevailed along the Central Andean margin during Pangaea break-up.

  15. Evaluation of antihyperglycemia and antihypertension potential of native Peruvian fruits using in vitro models.

    PubMed

    Pinto, Marcia Da Silva; Ranilla, Lena Galvez; Apostolidis, Emmanouil; Lajolo, Franco Maria; Genovese, Maria Inés; Shetty, Kalidas

    2009-04-01

    Local food diversity and traditional crops are essential for cost-effective management of the global epidemic of type 2 diabetes and associated complications of hypertension. Water and 12% ethanol extracts of native Peruvian fruits such as Lucuma (Pouteria lucuma), Pacae (Inga feuille), Papayita arequipeña (Carica pubescens), Capuli (Prunus capuli), Aguaymanto (Physalis peruviana), and Algarrobo (Prosopis pallida) were evaluated for total phenolics, antioxidant activity based on 2, 2-diphenyl-1-picrylhydrazyl radical scavenging assay, and functionality such as in vitro inhibition of alpha-amylase, alpha-glucosidase, and angiotensin I-converting enzyme (ACE) relevant for potential management of hyperglycemia and hypertension linked to type 2 diabetes. The total phenolic content ranged from 3.2 (Aguaymanto) to 11.4 (Lucuma fruit) mg/g of sample dry weight. A significant positive correlation was found between total phenolic content and antioxidant activity for the ethanolic extracts. No phenolic compound was detected in Lucuma (fruit and powder) and Pacae. Aqueous extracts from Lucuma and Algarrobo had the highest alpha-glucosidase inhibitory activities. Papayita arequipeña and Algarrobo had significant ACE inhibitory activities reflecting antihypertensive potential. These in vitro results point to the excellent potential of Peruvian fruits for food-based strategies for complementing effective antidiabetes and antihypertension solutions based on further animal and clinical studies.

  16. Protective efficacy of oral whole-cell/recombinant-B-subunit cholera vaccine in Peruvian military recruits.

    PubMed

    Sanchez, J L; Vasquez, B; Begue, R E; Meza, R; Castellares, G; Cabezas, C; Watts, D M; Svennerholm, A M; Sadoff, J C; Taylor, D N

    1994-11-05

    The cholera epidemic in South America has reinforced the need for safe and effective oral vaccines. In a randomised, double-blind, placebo-controlled efficacy trial among 1563 Peruvian military recruits we have investigated the protective efficacy of an oral inactivated whole-cell/recombinant-B-subunit (WC/rBS) cholera vaccine. Participants were given two oral doses of cholera vaccine or Escherichia coli K12 placebo, with an interval of 7-14 days. 1426 (91%) subjects received the two prescribed doses and were followed up for a mean of 18 weeks (median 21 weeks). After vaccination, Vibrio cholerae O1 El Tor Ogawa was isolated from 17 subjects with diarrhoea. 16 of the cholera cases occurred 2 weeks or longer after the second dose of vaccine (14 placebo recipients, 2 vaccinees). We also detected 14 symptomless infections (11 [7 placebo recipients, 4 vaccinees]) 2 weeks or longer after the second dose. The vaccine had significant protective efficacy against cholera (86% [95% CI 37-97], p < 0.01) but not against symptomless infection (42% [-96 to 85]). All cholera cases were in people of blood group O, who made up 76% of the study population (p < 0.01). Two doses of WC/rBS vaccine, given 1 to 2 weeks apart, provide rapid, short-term protection against symptomatic cholera in adult South Americans, who are predominantly of blood group O. Long-term efficacy studies in Peruvian adults and children are under way.

  17. Developing integrated approaches to climate change adaptation in rural communities of the Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Huggel, Christian

    2010-05-01

    Over centuries, Andean communities have developed strategies to cope with climate variability and extremes, such as cold waves or droughts, which can have severe impacts on their welfare. Nevertheless, the rural population, living at altitudes of 3000 to 4000 m asl or even higher, remains highly vulnerable to external stresses, partly because of the extreme living conditions, partly as a consequence of high poverty. Moreover, recent studies indicate that climatic extreme events have increased in frequency in the past years. A Peruvian-Swiss Climate Change Adaptation Programme in Peru (PACC) is currently undertaking strong efforts to understand the links between climatic conditions and local livelihood assets. The goal is to propose viable strategies for adaptation in collaboration with the local population and governments. The program considers three main areas of action, i.e. (i) water resource management; (ii) disaster risk reduction; and (iii) food security. The scientific studies carried out within the programme follow a highly transdisciplinary approach, spanning the whole range from natural and social sciences. Moreover, the scientific Peruvian-Swiss collaboration is closely connected to people and institutions operating at the implementation and political level. In this contribution we report on first results of thematic studies, address critical questions, and outline the potential of integrative research for climate change adaptation in mountain regions in the context of a developing country.

  18. [Calf circumference and its association with gait speed in elderly participants at Peruvian Naval Medical Center].

    PubMed

    Díaz Villegas, Gregory Mishell; Runzer Colmenares, Fernando

    2015-01-01

    To evaluate the association between calf circumference and gait speed in elderly patients 65 years or older at Geriatric day clinic at Peruvian Centro Médico Naval. Cross-sectional, retrospective study. We assessed 139 participants, 65 years or older at Peruvian Centro Médico Naval including calf circumference, gait speed and Short Physical Performance Battery. With bivariate analyses and logistic regression model we search for association between variables. The age mean was 79.37 years old (SD: 8.71). 59.71% were male, the 30.97% had a slow walking speed and the mean calf circumference was 33.42cm (SD: 5.61). After a bivariate analysis, we found a calf circumference mean of 30.35cm (SD: 3.74) in the slow speed group and, in normal gait group, a mean of 33.51cm (SD: 3.26) with significantly differences. We used logistic regression to analyze association with slow gait speed, founding statistically significant results adjusting model by disability and age. Low calf circumference is associated with slow speed walk in population over 65 years old. Copyright © 2014. Published by Elsevier Espana.

  19. Necessity of the Ridge for the Flat Slab Subduction: Insights from the Peruvian Flat Slab

    NASA Astrophysics Data System (ADS)

    Knezevic Antonijevic, S.; Wagner, L. S.; Beck, S. L.; Long, M. D.; Zandt, G.; Tavera, H.

    2014-12-01

    Flattening of the subducting plate has been linked to the formation of various geological features, including basement-cored uplifts, the cessation of arc volcanism, ignimbrite flare-ups, and the formation of high plateaus and ore deposits [Humphreys et al., 2003; Gutscher et al., 2000; Rosenbaum et al., 2005]. However, the mechanism responsible for the slab flattening is still poorly understood. Here we focus on the Peruvian flat slab, where the Nazca plate starts to bend at ~80 km depth and travels horizontally for several hundred kilometers, at which point steep subduction resumes. Based on a 1500 km long volcanic gap and intermediate depth seismicity patterns, the Peruvian flat slab appears to have the greatest along-strike extent and, therefore, has been suggested as a modern analogue to the putative flat slab during the Laramide orogeny in the western United States (~80-55 Ma). Combining 3D shear wave velocity structure and Rayleigh wave phase anisotropy between ~10° and 18° S, we find that the subducting Nazca plate is not uniformly flat along the entire region, but fails to the north of the subducting Nazca Ridge. Our results show that, in combination with trench retreat, rapid overriding plate motion, and/or presence of a thick cratonic root, the subduction of buoyant overthickened oceanic crust, such as the Nazca Ridge, is necessary for the formation and sustainability of flat slabs. This finding has important implications for the formation of flat slabs both past and present.

  20. Bender-gradual scoring system: performance of Brazilian and Peruvian children.

    PubMed

    dos Santos, Acácia Aparecida Angeli; Noronha, Ana Paula Porto; Rueda, Fabián Javier Marín; Segovia, José Livia

    2014-06-01

    This is a transcultural study of a sample of Peruvian and Brazilian children using the Bender-Gradual Scoring System (B-SPG), which considers shape distortion as the only aspect to be analyzed, assuming that perceptual-motor maturity is independent of cultural context. The study verified that the scoring system has psychometric qualities such that it may be applied in another country. The sample consisted of 231 children, ages 6 to 10 yr., 108 from different districts of the province Lima in Peru, and 123 children from three states in Brazil. During test application, the figures were projected to children in groups. Scoring the protocols for errors was conducted by psychologists experienced in interpreting and correcting the Bender-SPG, who rigorously followed instructions in Portuguese and Spanish. The results obtained with Differential Item Functioning (DIF) analysis indicated that Figures 1 and 4 presented DIF, one favoring Brazilian children and the other Peruvian children. Thus, it was concluded that the overall scores did not favor either population and the Bender-SPG could be used to evaluate perceptual-motor maturity in both countries.

  1. Life cycle assessment based evaluation of regional impacts from agricultural production at the Peruvian coast.

    PubMed

    Bartl, Karin; Verones, Francesca; Hellweg, Stefanie

    2012-09-18

    Crop and technology choices in agriculture, which largely define the impact of agricultural production on the environment, should be considered in agricultural development planning. A life cycle assessment of the dominant crops produced in a Peruvian coastal valley was realized, in order to establish regionalized life cycle inventories for Peruvian products and to provide the basis for a regional evaluation of the impacts of eutrophication, acidification, human toxicity, and biodiversity loss due to water use. Five scenarios for the year 2020 characterized by different crop combinations and irrigation systems were considered as development options. The results of the regional assessment showed that a business-as-usual scenario, extrapolating current trends of crop cultivation, would lead to an increase in nitrate leaching with eutrophying effects. On the other hand, scenarios of increased application of drip irrigation and of mandarin area expansion would lead to a decrease in nitrate leaching. In all scenarios the human toxicity potential would decrease slightly, while an increase in irrigation water use would benefit the biodiversity of a nearby groundwater-fed wetland. Comparisons with results from other studies confirmed the importance of regionalized life cycle inventories. The results can be used as decision support for local farmers and authorities.

  2. A phytosociological analysis and synopsis of the dry woodlands and succulent vegetation of the Peruvian Andes.

    PubMed

    Galán-DE-Mera, Antonio; Sánchez-Vega, Isidoro; Linares-Perea, Eliana; Campos, José; Montoya, Juan; Vicente-Orellana, José A

    2016-01-01

    A phytosociological approach to dry forest and cactus communities on the occidental slopes of the Peruvian Andes is presented in base of 164 plots carried out following the Braun-Blanquet method. From them, 52 have been made recently, and the other 112 were taken from the literature. After a multivariate analysis, using a hierarchical clustering and a detendred correspondence analysis, the Acacio-Prosopidetea class (dry forest and cactus communities, developed on soils with some edaphic humidity or precipitations derived from El Niño Current), the Opuntietea sphaericae class (cactus communities of central and southern Peru, on few stabilized rocky or sandy soils) and the Carico-Caesalpinietea class (dry forests of the Peruvian coastal desert, influenced by the maritime humidity of the cold Humboldt Current), are differentiated. Within the Acacio-Prosopidetea class, two alliances are commented: the Bursero-Prosopidion pallidae (with two new associations Loxopterygio huasanginis-Neoraimondietum arequipensis and Crotono ruiziani-Acacietum macracanthae), and the new alliance Baccharido-Jacarandion acutifoliae (with the new associations Armatocereo balsasensis-Cercidietum praecocis and Diplopterydo leiocarpae-Acacietum macracanthae). For the Opuntietea sphaericae class, the association Haageocereo versicoloris-Armatocereetum proceri (Espostoo-Neoraimondion) is described on the basis of plots from hyperarid localities of central Peru. Finally, a typological classification of the studied plant communities is given.

  3. An Ancestral Language to Speak with the "Other": Closing down Ideological Spaces of a Language Policy in the Peruvian Andes

    ERIC Educational Resources Information Center

    Zavala, Virginia

    2014-01-01

    Using a multilayered, ethnographic and critical approach to language policy and planning, this article examines a language policy favoring Quechua in Apurímac in the Southern Peruvian Andes, which is being imagined as an integrated community unified by the local language. This study presents a case in which top-down policies open up ideological…

  4. Massive parasitism by Gussevia tucunarense (Platyhelminthes: Monogenea: Dactylogyridae) in fingerlings of bujurqui-tucunare cultured in the Peruvian Amazon.

    PubMed

    Mathews, Patrick D; Mertins, Omar; Mathews, John P D; Orbe, Rosa I

    2013-06-01

    A high infestation of the monogenean Gussevia tucunarense in a cultivation of bujurqui-tucunare was reported. The prevalence was 100%. The mean intensity and abundance of the parasite was 164.4 of parasites per individual. This is the first report of a high infestation by G. tucunarense in C. semifasciatus cultured from the Peruvian Amazon.

  5. The Quechua Manta Pouch: A Caretaking Practice for Buffering the Peruvian Infant against the Multiple Stressors of High Altitude.

    ERIC Educational Resources Information Center

    Tronick, E. Z.; And Others

    1994-01-01

    Describes the caretaking practices employed by the Peruvian Quechua mountain people, who swaddle infants in cloths and blankets (known as a manta pouch) to protect them from the harsh and frigid environment. The practices of 14 mother-infants pairs are examined in detail, and the benefits and drawbacks of the manta pouch are examined. (MDM)

  6. An Ancestral Language to Speak with the "Other": Closing down Ideological Spaces of a Language Policy in the Peruvian Andes

    ERIC Educational Resources Information Center

    Zavala, Virginia

    2014-01-01

    Using a multilayered, ethnographic and critical approach to language policy and planning, this article examines a language policy favoring Quechua in Apurímac in the Southern Peruvian Andes, which is being imagined as an integrated community unified by the local language. This study presents a case in which top-down policies open up ideological…

  7. Peruvian Education at a Crossroads: Challenges and Opportunities for the 21st Century. A World Bank Country Study.

    ERIC Educational Resources Information Center

    Wu, Kin Bing

    Peruvian education achieved notable successes in the late 20th century, with primary education reaching almost all children and secondary institutions enrolling about 80 percent of 12- to 16-year-olds. Public expenditure on education increased steadily in the 1990s but was still significantly less than the Latin American average. This report…

  8. Development of Teleological Explanations in Peruvian Quechua-Speaking and U.S. English-Speaking Preschoolers and Adults

    ERIC Educational Resources Information Center

    Sánchez Tapia, Ingrid; Gelman, Susan A.; Hollander, Michelle A.; Manczak, Erika M.; Mannheim, Bruce; Escalante, Carmen

    2016-01-01

    Teleological reasoning involves the assumption that entities exist for a purpose (giraffes have long necks for reaching leaves). This study examines how teleological reasoning relates to cultural context, by studying teleological reasoning in 61 Quechua-speaking Peruvian preschoolers (M[subscript age] = 5.3 years) and adults in an indigenous…

  9. Development of Teleological Explanations in Peruvian Quechua-Speaking and U.S. English-Speaking Preschoolers and Adults

    ERIC Educational Resources Information Center

    Sánchez Tapia, Ingrid; Gelman, Susan A.; Hollander, Michelle A.; Manczak, Erika M.; Mannheim, Bruce; Escalante, Carmen

    2016-01-01

    Teleological reasoning involves the assumption that entities exist for a purpose (giraffes have long necks for reaching leaves). This study examines how teleological reasoning relates to cultural context, by studying teleological reasoning in 61 Quechua-speaking Peruvian preschoolers (M[subscript age] = 5.3 years) and adults in an indigenous…

  10. Simultaneous Infection with Leishmania (Viannia) braziliensis and L. (V.) lainsoni in a Peruvian Patient with Cutaneous Leishmaniasis

    PubMed Central

    Veland, Nicolas; Valencia, Braulio Mark; Alba, Milena; Adaui, Vanessa; Llanos-Cuentas, Alejandro; Arevalo, Jorge; Boggild, Andrea K.

    2013-01-01

    Conventional understanding suggests that simultaneous infection with more than one species of Leishmania is unlikely. In Peru, co-infections are clinically relevant because causative species dictates prognosis, treatment response, and follow-up. We describe a case of Leishmania (Viannia) braziliensis and L. (V.) lainsoni co-infection in a Peruvian patient with cutaneous leishmaniasis. PMID:23382155

  11. The Quechua Manta Pouch: A Caretaking Practice for Buffering the Peruvian Infant against the Multiple Stressors of High Altitude.

    ERIC Educational Resources Information Center

    Tronick, E. Z.; And Others

    1994-01-01

    Describes the caretaking practices employed by the Peruvian Quechua mountain people, who swaddle infants in cloths and blankets (known as a manta pouch) to protect them from the harsh and frigid environment. The practices of 14 mother-infants pairs are examined in detail, and the benefits and drawbacks of the manta pouch are examined. (MDM)

  12. [Peruvian scientific production in medicine and collaboration networks, analysis of the Science Citation Index 2000-2009].

    PubMed

    Huamaní, Charles; Mayta-Tristán, Percy

    2010-09-01

    To describe the Peruvian scientific production in indexed journals in the Institute for Scientific Information (ISI) and the characteristics of the institutional collaborative networks. All papers published in the ISI database (Clinical Medicine collection) were included during 2000 to 2009 with at least one author with a Peruvian affiliation. The publication trend, address of corresponding author, type of article, institution, city (only for Peru), and country were evaluated. The collaborative networks were analized using the Pajek® software. 1210 papers were found, increasing from 61 in 2000 to 200 in 2009 (average of 121 articles/year). 30.4% articles included a corresponding author from a Peruvian institution. The average of authors per article was 8.3. Original articles represented 82.1% of total articles. Infectious diseases-related journals concentrated most of the articles. The main countries that collaborate with Peru are: USA (60.4%), England (12.9%), and Brazil (8.0%). Lima concentrated 94.7% of the publications and three regions (Huancavelica, Moquegua and Tacna) did not register any publication. Only two universities published more than one article/year and four institutions published more than 10 articles/year. Universidad Peruana Cayetano Heredia published 45% of the total number of articles, being the most productive institution and which concentrated the most number of collaborations with foreign institutions. The ministry of Health--including all dependencies--published 37.3% of the total number of publications. There is a higher level of collaboration with foreign institutions rather than local institutions. The Peruvian scientific production in medicine represented in the ISI database is very low but growing, and is concentrated in Lima and in a few institutions. The most productive Peruvian institutions collaborate more intensively with foreign journals rather than local institutions.

  13. Peruvian sediments as recorders of an evolving hiatus for the last 22 thousand years

    NASA Astrophysics Data System (ADS)

    Erdem, Zeynep; Schönfeld, Joachim; Glock, Nicolaas; Dengler, Marcus; Mosch, Thomas; Sommer, Stefan; Elger, Judith; Eisenhauer, Anton

    2016-04-01

    The Peruvian continental margin is characterized by the presence of one of the strongest and most distinct Oxygen Minimum Zones (OMZs) in today's oceans. Therefore, it has long been in the focus of oceanographic and geological investigations. Observations indicate that OMZs are expanding in relation with currently changing climate. To advance understanding of the temporal evolution of OMZs and climate change, complete paleoceanographic and palaeoclimatological reconstructions are needed. However, the development of paleoenvironmental scenarios for the period since the Last Glacial Maximum at this region was hampered by a ubiquitous hiatus and short-term interruptions of the stratigraphical record. In the present study, we combined the stratigraphical information from 31 sediment cores from the Peruvian margin located between 3 and 18°S and water depths of 90 to 1300 m within and below today's OMZ, in order to determine the extent of the hiatus and assess the responsible mechanisms. A widespread unconformity and related erosional features, omission surfaces and phosphorites, were observed in sediment cores from the area south of 7°S, depicting a prograding feature on the continental slope from south to north during the deglaciation. Combining recent oceanographic and sedimentological observations, it is inferred that, tide-topography interaction and resulting non-linear internal waves (NLIWs) shape the slope by erosion, carry sediments upslope or downslope and leave widespread phosphoritic lag sediments, while the Peru Chile Undercurrent (PCUC) transports the resuspended sediments southward causing non-deposition. This exceptional sedimentary regime makes the Peruvian margin a modern analogue for such environments. Overall, our compilation of downcore records showed that enhanced bottom currents due to tide-topography interaction were progressively evolving and affected a wider area with the onset of the last deglaciation. Elevated tidal amplitudes and variability

  14. [A phytosociological interpretation of vegetation from sandy hills of the Peruvian desert].

    PubMed

    Galán de Mera, Antonio; Linares Perea, Eliana; Campos de la Cruz, José; Vicente Orellana, José Alfredo

    2011-06-01

    The vegetation of the sandy hills ("lomas") constitutes the main originality of the Peruvian and Chilean desert with a high number of endemics that shapes the vicarious associations. In this work, a phytosociological view of sandy environments of the Peruvian coastal desert is presented. According to the Braun-Blanquet method, we have made up 32 phytosociological inventories and added 138 ones from others authors. In each inventory, we have analyzed its floristic composition and ecological parameters, as altitude, soil and geomorphology. All releves were synthesized in a table to deduce the different associations, higher phytosociological units, and the distribu tion of its flora along the Peruvian coast and the Andean Cordillera. Using the Shannon-Wiener diversity index, the diversity of this flora is discussed making a comparison with historical data about the use of the territory with livestock during pre-Inca and Inca cultures, and Spanish invasion. As a result, two associations from Southern Peru -Nolanetum scaposo-spathulatae and Palauetum camanensis-weberbaueri-, two alliances -Nolanion humifusae from central Peru, and Nolanion spathulatae from the Southern Peru- and a new order -Tetragonio crystallinae-Plantaginetalia limensis- are described. In Nolanetum scaposo-spathulatae, Dictyophragnus englerianus, Leptoglossis lomana, Nolana scaposa, N. spathulata, Palaua velutina and Tetragonia vestita are the main characteristics, while in Palauetum camanensis-weberbaueri association N. scaposa and P. velutina are replaced by Palaua camanensis and P. weberbaueri. Nolanion humifusae alliance integrates species as Geranium limae, Hymenocallis amancaes, Nolana humifusa, N. latipes, Palaua rhombifolia or Villanova oppositifolia. Likewise, Cistanthe weberbaueri, Cryptantha parviflora, Hoffmannseggia miranda, Lupinus mollendoensis, Nolana confinis, N. pallidula, N. scaposa, N. spathulata, Palaua camanensis, P. velutina, P. weberbaueri, Tetragonia vestita and

  15. Wind Disturbance Produced Changes in Tree Species Assemblage in the Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Rifai, S. W.; Chambers, J. Q.; Negron Juarez, R. I.; Ramirez, F.; Tello, R.; Alegria Muñoz, W.

    2010-12-01

    Wind disturbance has been a frequently overlooked abiotic cause of mass tree mortality in the Amazon basin. In the Peruvian Amazon these wind disturbances are produced by meteorological events such as convective systems. Downbursts for example produce short term descendent wind speeds that can be in excess of 30 m s-1. These are capable of producing tree blowdowns which have been reported to be as large as 33 km2 in the Amazon basin. We used the chronosequence of Landsat Satellite imagery to find and locate where these blowdowns have occurred in the Loreto region of the Peruvian Amazon. Spectral Mixture Analysis was used to estimate the proportion landcover of green vegetation, non-photosynthetic vegetation (NPV), soil and shade in each pixel. The change in NPV was calculated by subtracting the NPV signal in the Landsat image prior to the blowdown occurrence, from the image following the disturbance. Our prior research has established a linear relationship between tree mortality and change in NPV. It is hypothesized that these mass tree mortality events result in changes in the tree species assemblage of affected forests. Here we present preliminary tree species assemblage data from two sites in the Peruvian Amazon near Iquitos, Peru. The site (ALP) at the Allpahuayo Mishana reserve (3.945 S, 73.455 W) is 30 km south of Iquitos, Peru, and hosts the remnants of a 50 ha blowdown that occurred in either 1992 or 1993. Another site (NAPO) on the Napo river about 60 km north of Iquitos, is the location of an approximately 300 ha blowdown that occurred in 1998. At each site, a 3000 m x 10 m transect encompassing non disturbed and disturbed areas was installed, and trees greater than 10 cm diameter at breast height were measured for diameter, height and were identified to the species. Stem density of trees with diameter at breast height > 10 cm, and tree height appear to be similar both inside and outside the blowdown affected areas of the forests at both sites. At the ALP

  16. Three-Dimensional Gravity and Magnetic Modelling Along the Peruvian Margin

    NASA Astrophysics Data System (ADS)

    Dehghani, A.; Sabetian, R.

    2015-12-01

    The gravity and magnetic models are constructed for three areas along the Peruvian margin between 7.25°S and 16.75°S and are based on the all available wide-angle seismic velocity models. The gravity and magnetic models image nearly the whole margin which has been only partly resolved with geophysical methods up to now. The continental margin is characterized by positive free-air anomalies of varying amplitudes, indicating that the margin has been shaped by the subduction of different features on the Nazca Plate. In the Yaquina Area (7.25°S to 11°S) gravity anomalies caused by the Trujillo Trough and the Mendaña Fracture Zone are successfully modelled with remarkable undulations in the layer geometry of the oceanic crust. Along the continental margin, especially in the Lima Area (10.50°S to 14.40°S), strong undulations of the lower continental crust influence the upper sedimentary layers and support the development of basins along the Peruvian margin. The theory stating that the Peruvian margin is uplifted by the subducting Nazca Ridge is supported by gravity modelling. Consequently the buoyant Nazca Ridge is, at least partly, responsible for the extended region of flat subduction. The thickened and slightly asymmetrical crust of the Nazca Ridge is envisaged in gravity modelling. In the Nazca Ridge Area (14.25°S to 16.75°S) no accretionary prism is modelled. We conclude that the ridge is eroding the continental margin; furthermore the subduction of eroded sediments is probable. Gravity modelling suggests that the Nazca Ridge has fractured the continental margin. North of the ridge, in the Lima Area, a rather uniform accretionary complex is observed. This indicates that, after the margin was eroded by the southwards moving Nazca Ridge, the prism rapidly reached its stable size. In the Yaquina Area an accretionary prism is modelled in the whole research area but local variations of its location and structure indicate the former erosive influence on the

  17. Nutritional status, physical performance and disability in the elderly of the Peruvian Andes.

    PubMed

    Tramontano, Alessandra; Veronese, Nicola; Giantin, Valter; Manzato, Enzo; Rodriguez-Hurtado, Diana; Trevisan, Caterina; De Zaiacomo, Francesca; Sergi, Giuseppe

    2016-12-01

    Although nutritional status plays an important part in the physical performance and disability of older people, this relationship has been little studied in developing countries. A study on the effects of nutritional status on the physical performance and functional status of elderly people living in rural areas of the Peruvian Andes. The study concerned 222 people aged ≥65 years living in a rural area of the Peruvian Andes. The Mini-Nutritional Assessment (MNA) was used to classify participants as malnourished (MNA <= 17), at risk of malnutrition (MNA 18-23), or well-nourished (MNA>= 24). The short physical performance battery (SPPB) and six-minute walking test (6MWT) were used to measure participants' physical performance. Disabilities were investigated by assessing participants' self-reported difficulty in performing one or more basic activities of daily living (ADL), and instrumental activities of daily living (IADL). The prevalence of malnutrition was 9.4 %, and more than half of our samples were at risk of malnutrition. After adjusting for potential confounders, malnourished individuals performed significantly worse than the other MNA groups in the SPPB (p for trend=0.001), 6MWT and IADL (p for trend < 0.0001 for both outcomes), but not in the ADL (p for trend = 0.23). Taking the well-nourished for reference, and after adjusting for potential confounders, malnutrition was significantly associated with disability in IADL (OR 5.36, 95 % CI 1.02-56.94; p = 0.05), and poor performance in the 6MWT (OR 2.73, 95 % CI 1.06-12.08; p = 0.03) and SPPB (OR 4.94, 95 % CI 1.01-24.07; p = 0.04). Poor nutritional status was found significantly associated with poor physical performance and poor functional status in elderly Peruvian individuals.

  18. An Analysis of the Doctrinal Changes that the Peruvian Army Implemented Fighting Counterinsurgency Operations Against the Sendero Luminoso Insurgency Since 2001

    DTIC Science & Technology

    2014-06-13

    the SL organization. Those considered for this research are: 1. La Republica Peruvian Digital Newspaper provides detailed information about SL...57Education and Doctrine Command Peruvian Army, CG 35-51-10, 3-1 to 3-10. 58La Republica , “Death of Comrade William a Blow...Peru Presidency, http://www.presidencia.gob.pe/mensaje-a-la-nacion-del-senor-presidente-de-la- republica - ollanta-humala-tasso-con-motivo-del-191d

  19. Geographic distribution and possible taxonomic distinction of Callicebus torquatus populations (Pitheciidae: Primates) in Peruvian Amazonia.

    PubMed

    Aquino, Rolando; Terrones, Wagner; Cornejo, Fanny; Heymann, Eckhard W

    2008-12-01

    Population densities of yellow-handed titi monkey (Callicebus torquatus) were estimated using transect census methods. Densities were 2.8 individuals/km(2 )in the upper Rio Itaya basin and 2.5 individuals/km(2) in the lower Rio Algodón basin. Group size varied from two to five individuals, with an average of 2.9 individuals per group at the Rio Itaya. Groups were generally composed of two adults, probably the reproductive pair, with progeny from one to three previous birth seasons. Although the Rio Itaya population is phenotypically identical to populations from the rivers Nanay and Tigre, it differs from population on the rivers Napo and Putumayo. This suggests the existence of two disjunct populations of C. torquatus in Peruvian Amazonia whose taxonomic status warrants further examination.

  20. Structural Factors That Increase HIV/STI Vulnerability Among Indigenous People in the Peruvian Amazon

    PubMed Central

    Orellana, E. Roberto; Alva, Isaac E.; Cárcamo, Cesar P.; García, Patricia J.

    2015-01-01

    We examined structural factors—social, political, economic, and environmental—that increase vulnerability to HIV among indigenous people in the Peruvian Amazon. Indigenous adults belonging to 12 different ethnic groups were purposively recruited in four Amazonian river ports and 16 indigenous villages. Qualitative data revealed a complex set of structural factors that give rise to environments of risk where health is constantly challenged. Ferryboats that cross Amazonian rivers are settings where unprotected sex—including transactional sex between passengers and boat crew and commercial sex work—often take place. Population mobility and mixing also occurs in settings like the river docks, mining sites, and other resource extraction camps, where heavy drinking and unprotected sex work are common. Multilevel, combination prevention strategies that integrate empirically based interventions with indigenous knowledge are urgently needed, not only to reduce vulnerability to HIV transmission, but also to eliminate the structural determinants of indigenous people’s health. PMID:23925407

  1. Peruvian Red Uakaris (Cacajao calvus ucayalii) Are Not Flooded-Forest Specialists

    PubMed Central

    Aquino, Rolando

    2010-01-01

    In the literature, particularly in primatological books, the Peruvian red uakari (Cacajao calvus ucayalii) is generally considered as a species that is specialized on living in flooded forest, despite existing evidence to the contrary. Here we review all available information on habitats where Cacajao calvus ucayalii have been observed. Most sightings are from terra firme, including palm swamps, or from mixed habitats, including terra firme and flooded forest. Therefore, we conclude that the species is not a flooded-forest specialist, but is flexible in its habitat requirements and generally uses terra firme forests or a mixture of habitats. Proper recognition of habitat requirements is important for understanding the ecoethological adaptations of a species and for appropriate conservation measures. PMID:20949117

  2. Molecular and morphological evidence of Taenia omissa in pumas (Puma concolor) in the Peruvian Highlands.

    PubMed

    Gomez-Puerta, Luis Antonio; Alarcon, Virgilio; Pacheco, Joel; Franco, Francisco; Lopez-Urbina, Maria Teresa; Gonzalez, Armando Emiliano

    2016-01-01

    A total of 41 cestodes were collected during necropsy examination on 2 pumas (Puma concolor) that were found in 2 communities in Canchis province, Cuzco region, Peru, at 4500 meters above sea level (Peruvian Andes). The cestodes were evaluated morphologically and molecularly. A fragment of the mitochondrial cytochrome c oxidase subunit 1 gene (cox1) was used as a genetic marker. All the cestodes were identified as Taenia omissa. In the present report, we give a brief description by molecular and morphological diagnosis of the cestodes and compare nucleotide sequences with previous isolates from GenBank. Upon comparison, the sequences showed a difference in the cox1 gene of 5.1 to 5.3% with other teniids sequences. This finding constitutes the first report of T. omissa in Peru and expands the geographic distribution of this parasite.

  3. RISK FACTORS FOR HTLV-II INFECTION IN PERUVIAN MEN WHO HAVE SEX WITH MEN

    PubMed Central

    ZUNT, JOSEPH R.; LA ROSA, ALBERTO M.; PEINADO, JESÚS; LAMA, JAVIER R.; SUAREZ, LUIS; PUN, MONICA; CABEZAS, CESAR; SANCHEZ, JORGE

    2009-01-01

    Human T-cell lymphotropic virus type-II (HTLV-II) infection is endemic in indigenous groups in the Americas and injection drug users (IDUs) worldwide. In Peru, HTLV-II infection was previously identified in two indigenous Amazonians. We examined risk factors for HTLV-II infection in 2,703 Peruvian men who have sex with men (MSM): 35 (1.3%) were HTLV-II positive. HTLV-II infection was associated with syphilis, HSV-2 infection, unprotected receptive anal intercourse, and older age. This is the first report of HTLV-II in a non-indigenous non-IDU population in Peru. Additional studies are needed to determine if HTLV-II is a sexually transmitted infection in this and other sexually active populations. PMID:16687704

  4. TB in Vulnerable Populations: The Case of an Indigenous Community in the Peruvian Amazon.

    PubMed

    Gianella, Camila; Ugarte-Gil, César; Caro, Godofredo; Aylas, Rula; Castro, César; Lema, Claudia

    2016-06-01

    This article analyzes the factors associated with vulnerability of the Ashaninka, the most populous indigenous Peruvian Amazonian people, to tuberculosis (TB). By applying a human rights-based analytical framework that assesses public policy against human rights standards and principles, and by offering a step-by-step framework for a full assessment of compliance, it provides evidence of the relationship between the incidence of TB among the Ashaninka and Peru's poor level of compliance with its human rights obligations. The article argues that one of the main reasons for the historical vulnerability of the Ashaninka to diseases such as TB is a lack of political will on the part of the national government to increase public health spending, ensure that resources reach the most vulnerable population, and adopt and invest in a culturally appropriate health system.

  5. Cephalometric norms from posteroanterior Ricketts' cephalograms from Hispanic Americans Peruvian non adult patients.

    PubMed

    Pérez, Iván E; Chávez, Allison K; Ponce, Darío

    2011-01-01

    The purpose of the present study was to describe the posteroanterior cephalometric norm values from Hispanic Americans Peruvian non adults patients between years 2009 to 2010, identify possible differences between sexes and compare our results with similar studies in the literature. Data from posteroanterior cephalograms from 318 patients (177 females and 141 males) between 9 and 18 years old were collected from our database; mean and standard deviation were calculated for each gender and age group. Independent samples T-test found statistically significant differences between males and females results in the intermolar width, right molar to maxillae distance, nasal width, nasal height, maxillary width, mandibular width and facial width. statistically differences between sexes were found in seven from twelve transversal measurements. The norm values found in this study are similar to those reported by Ricketts'.

  6. Traditional use of the Andean flicker (Colaptes rupicola) as a galactagogue in the Peruvian Andes

    PubMed Central

    Froemming, Steve

    2006-01-01

    This paper explores the use of the dried meat and feathers of the Andean Flicker (Colaptes rupicola) to increase the milk supply of nursing women and domestic animals in the Andes. The treatment is of preColumbian origin, but continues to be used in some areas, including the village in the southern Peruvian highlands where I do ethnographic research. I explore the factors giving rise to and sustaining the practice, relate it to other galactagogues used in the Andes and to the use of birds in ethnomedical and ethnoveterinary treatments in general, and situate it within the general tendency in the Andes and elsewhere to replicate human relations in the treatment of valuable livestock. The bird's use as a galactagogue appears to be motivated by both metaphorical associations and its perceived efficacy, and conceptually blends human and animal healthcare domains. PMID:16677398

  7. Accelerating to Zero: Strategies to Eliminate Malaria in the Peruvian Amazon

    PubMed Central

    Quispe, Antonio M.; Llanos-Cuentas, Alejandro; Rodriguez, Hugo; Clendenes, Martin; Cabezas, Cesar; Leon, Luis M.; Chuquiyauri, Raul; Moreno, Marta; Kaslow, David C.; Grogl, Max; Herrera, Sócrates; Magill, Alan J.; Kosek, Margaret; Vinetz, Joseph M.; Lescano, Andres G.; Gotuzzo, Eduardo

    2016-01-01

    In February 2014, the Malaria Elimination Working Group, in partnership with the Peruvian Ministry of Health (MoH), hosted its first international conference on malaria elimination in Iquitos, Peru. The 2-day meeting gathered 85 malaria experts, including 18 international panelists, 23 stakeholders from different malaria-endemic regions of Peru, and 11 MoH authorities. The main outcome was consensus that implementing a malaria elimination project in the Amazon region is achievable, but would require: 1) a comprehensive strategic plan, 2) the altering of current programmatic guidelines from control toward elimination by including symptomatic as well as asymptomatic individuals for antimalarial therapy and transmission-blocking interventions, and 3) the prioritization of community-based active case detection with proper rapid diagnostic tests to interrupt transmission. Elimination efforts must involve key stakeholders and experts at every level of government and include integrated research activities to evaluate, implement, and tailor sustainable interventions appropriate to the region.

  8. New focus of active transmission of Chagas disease in indigenous populations in the Peruvian Amazon basin.

    PubMed

    Cabrera, Rufino; Vega, Silvia; Valderrama, Yadira; Cabanillas, Karina; Fernández, Connie; Rodríguez, Omar; Del Aguila, César; Hernández, Jesús; Mendoza, Leonardo; Ramón Meza, Juan

    2013-01-01

    Several cases of acute Chagas disease (ACD) have been reported in the Peruvian Amazon basin. The objective was to describe and investigate 6 ACD cases in children from indigenous Amazon communities in the province of Datem del Marañón in Loreto department (2006-2010). The mean age was 3.6 years. All patients had fever, 4/6 hepatomegaly, 2/6 splenomegaly, and 5/6 had trypomastigotes of Trypanosoma cruzi on thick smears. The fatality rate was 33.3%. Rhodnius pictipes and Rhodnius robustus adults were found inside the homes and in the peri-domiciles. All cases reported were isolated cases. We report a new focus of ACD in indigenous populations.

  9. A Peruvian family with a high burden of HTLV-1-associated myelopathy/tropical spastic paraparesis

    PubMed Central

    Alvarez, Carolina; Verdonck, Kristien; Tipismana, Martín; Gotuzzo, Eduardo

    2015-01-01

    Human T-lymphotropic virus 1 (HTLV-1) is frequent in Peru; an estimated 1–2% of the Peruvian population carry this retrovirus. HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic disabling disease that affects about 1% of the carriers of HTLV-1. It is not yet known why some HTLV-1-infected people develop HAM/TSP while others do not. In this case report, we present a family with an unusually high burden of HAM/TSP: 5 (the 2 parents and 3 of their children) of 7 HTLV-1 carriers developed the same disease. We describe the clinical presentation and discuss the clustering of disease against the current knowledge of the pathogenesis of HAM/TSP. Families such as this may hold the key to discovering which factors trigger the development of HAM/TSP. PMID:26392440

  10. The microeconomics of sexual exploitation of girls and young women in the Peruvian Amazon.

    PubMed

    Mujica, Jaris

    2013-01-01

    This paper examines the sexual exploitation of girls and young women as an increasing phenomenon within the extractive industries of wood, oil, minerals and gas in Peruvian Amazonia. The analysis focuses on the city of Pucallpa and the northern part of the Ucayali River and aims to identify the social and economic dynamics underpinning the commercial sexual exploitation of female children and teenagers around the main river port. The study describes the local operating mechanisms of bars and restaurants in the port, the demand for and perceptions of the sexual exploitation of children and teenagers, and the economic logic that it entails. Using a discourse analytic approach, it is argued that this is a business whose profitability is tied to the trade in alcoholic beverages and foods and which responds to a set of family connections and networks.

  11. Climate change in Peruvian newspapers: The role of foreign voices in a context of vulnerability.

    PubMed

    Takahashi, Bruno; Meisner, Mark

    2013-05-01

    Media coverage of climate change has been an area of continued research during the last years, mostly with a focus on developed countries. This study attempts to contribute to this body of work by analyzing the coverage in a developing country. The study presents a content analysis of newspaper coverage of climate change in Peru through the study of frames, geographical focus, and climate change strategies (mitigation/adaptation). Additionally, the role of foreign voices is assessed by comparing the coverage by Peruvian reporters with the coverage by wire services, and by determining the types of sources present in the articles. Results show a prevalence of an effects frame, followed by a politics frame. Also, the study found a significant amount of stories originating from wire services. In general, coverage prioritizes mitigation strategies and policies while providing limited attention to adaptation, which can be insufficient for a highly vulnerable country.

  12. Nine genera of Eucnemidae (Coleoptera) new to Peru, with a key to Peruvian genera

    PubMed Central

    Muona, Jyrki; Linna, Ari; Sääksjärvi, Ilari E.

    2015-01-01

    Abstract Thirteen genera of Eucnemidae containing forty species were collected from the Iquitos region in Peru. Nine of the genera are new to the country: Rhagomicrus Fleutiaux, 1902, Adelorhagus Horn, 1890, Adelothyreus Chevrolat, 1867, Microrhagus Dejean, 1833, Dyscharachthis Blackburn, 1900, Heterotaxis Bonvouloir, 1871, Spinifornax Fleutiaux, 1926, Serrifornax Fleutiaux, 1926 and Maelodrus Fleutiaux, 1928. The previous eucnemid record from Peru contained eleven species in ten genera. Only one of the forty species caught, Entomophthalmus americanus Bonvouloir, was previously known and described from the country. Dyscharachthis, Maelodrus and Adelorhagus are recorded from South America for the first time. Many of the collected species seem to favor white-sand forest as their habitat. Possible reasons for this are discussed. A list of eucnemids from Peru is included, containing taxa already recorded from the country and also taxa that are likely to occur there. A key to the Peruvian genera is included. PMID:25834475

  13. Preferences for Intervention Among Peruvian Women in Intimate Partner Violence Relationships

    PubMed Central

    Cripe, Swee May; Espinoza, Damarys; Rondon, Marta B.; Jimenez, Maria Luisa; Sanchez, Elena; Ojeda, Nely; Sanchez, Sixto; Williams, Michelle A.

    2015-01-01

    We sought to identify what abused Peruvian women want or need as intervention strategies. We conducted five focus groups with thirty women with prior or current experience with intimate partner violence. Participants noted that abused women need compassionate support, professional counseling, informational and practical (e.g., work skills training, employment, shelter, financial support) interventions. We propose a two-tiered intervention strategy that includes community support groups and individual professional counseling. This strategy is intended to offer broad coverage, meeting the needs of large groups of women who experience abuse, while providing specialized counseling for those requiring intensive support. Respect for each woman’s autonomy in the decision-making process is a priority. Interventions targeted towards women and men should address structural factors that contribute to violence against women. PMID:25741931

  14. Distinct sesquiterpene pyridine alkaloids from in Salvadoran and Peruvian Celastraceae species.

    PubMed

    Callies, Oliver; Núñez, Marvin J; Perestelo, Nayra R; Reyes, Carolina P; Torres-Romero, David; Jiménez, Ignacio A; Bazzocchi, Isabel L

    2017-10-01

    As part of a bioprospecting program aimed at the discovery of undescribed natural products from Salvadoran and Peruvian flora, the phytochemical investigations of four Celastraceae species, Celastrus vulcanicola, Maytenus segoviarum, Maytenus jeslkii, and Maytenus cuzcoina, were performed. The current study reports the isolation and structural characterization of five previously undescribed macrolide sesquiterpene pyridine alkaloids, named vulcanicoline-A, cuzcoinine, vulcanicoline-B, jelskiine, and vulcanicoline-C, along with sixteen known alkaloids. The structures of the alkaloids were established by spectrometric and extensive 1D and 2D NMR spectroscopic analysis, including COSY, HSQC, HMBC, and ROESY experiments. The absolute configurations of alkaloids were proposed based on optical rotation sign, and biogenetic considerations. This study represents the first phytochemical analysis of Maytenus segoviarum. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Demographic and health attributes of the Nahua, initial contact population of the Peruvian Amazon.

    PubMed

    Culqui, Dante R; Ayuso-Alvarez, Ana; Munayco, Cesar V; Quispe-Huaman, Carlos; Mayta-Tristán, Percy; Campos, Juan de Mata Donado

    2016-01-01

    We present the case of the Nahua population of Santa Rosa de Serjali, Peruvian Amazon's population, considered of initial contact. This population consists of human groups that for a long time decided to live in isolation, but lately have begun living a more sedentary lifestyle and in contact with Western populations. There are two fully identified initial contact groups in Peru: the Nahua and the Nanti. The health statistics of the Nahua are scarce. This study offers an interpretation of demographic and epidemiological indicators of the Nahua people, trying to identify if a certain degree of health vulnerability exists. We performed a cross sectional study, and after analyzing their health indicators, as well as the supplemental qualitative analysis of the population, brought us to conclude that in 2006, the Nahua, remained in a state of health vulnerability.

  16. Structural factors that increase HIV/STI vulnerability among indigenous people in the Peruvian amazon.

    PubMed

    Orellana, E Roberto; Alva, Isaac E; Cárcamo, Cesar P; García, Patricia J

    2013-09-01

    We examined structural factors-social, political, economic, and environmental-that increase vulnerability to HIV among indigenous people in the Peruvian Amazon. Indigenous adults belonging to 12 different ethnic groups were purposively recruited in four Amazonian river ports and 16 indigenous villages. Qualitative data revealed a complex set of structural factors that give rise to environments of risk where health is constantly challenged. Ferryboats that cross Amazonian rivers are settings where unprotected sex-including transactional sex between passengers and boat crew and commercial sex work-often take place. Population mobility and mixing also occurs in settings like the river docks, mining sites, and other resource extraction camps, where heavy drinking and unprotected sex work are common. Multilevel, combination prevention strategies that integrate empirically based interventions with indigenous knowledge are urgently needed, not only to reduce vulnerability to HIV transmission, but also to eliminate the structural determinants of indigenous people's health.

  17. [Coinfection of dengue and leptospirosis in a girl from the peruvian amazon].

    PubMed

    Núñez-Garbín, Alexandra; Espinoza-Figueroa, Jossué; Sihuincha-Maldonado, Moisés; Suarez-Ognio, Luis

    2015-01-01

    We report the case of a 10 year old girl, born and raised in the city of Iquitos in Peru who presented with headache, fever, chills, musculoskeletal pain, mild epigastric pain, epistaxis and hematemesis. On physical examination, the patient was afebrile and in good general condition. Serological tests confirmed infection of dengue and leptospirosis. The patient received intravenous hydration with sodium chloride 0.9% and penicillin G sodium, achieving a favorable clinical course such that she was discharged a few days after admission to the hospital. Although these diseases are common in the Peruvian Amazon, the simultaneous presence of both in the pediatric population is little documented; therefore, a good clinical history and laboratory tests are important for diagnosis and treatment.

  18. [Publication of research projects for certification as medical specialists at a Peruvian university, 2007-2010].

    PubMed

    Ticse, Ray; Ygreda, Patricia; Samalvides, Frine

    2014-04-01

    In order to determine the frequency of publication in a scientific journal of the research projects done for medical specialty certification, a search was conducted in Google Scholar, Pubmed, biomedical databases and Peruvian medical society journals. These publications were research projects carried out by medical residents graduated from the Faculty of Medicine at the Universidad Peruana Cayetano Heredia, to obtain the certification of medical specialist. Of 351 medical residents graduated between the years 2007-2010, 199 (65.5%) completed their research project and 47 (23.6%) published it in a scientific journal. The "medicine" (non-surgical) specialty area had the highest frequency of publications. All publications were in Spanish journals, the majority in indexed journals in regional databases. We conclude that 23.6% of the research projects for certification as medical specialists are published, most often in low visibility journals.

  19. High Degree of Plasmodium vivax Diversity in the Peruvian Amazon Demonstrated by Tandem Repeat Polymorphism Analysis

    PubMed Central

    Kosek, Margaret; Yori, Pablo P.; Gilman, Robert H.; Calderon, Maritza; Zimic, Mirko; Chuquiyauri, Raul; Jeri, Cesar; Pinedo-Cancino, Viviana; Matthias, Michael A.; Llanos-Cuentas, Alejandro; Vinetz, Joseph M.

    2012-01-01

    Molecular tools to distinguish strains of Plasmodium vivax are important for studying the epidemiology of malaria transmission. Two sets of markers—tandem repeat (TR) polymorphisms and MSP3α—were used to study Plasmodium vivax in patients in the Peruvian Amazon region of Iquitos. Of 110 patients, 90 distinct haplotypes were distinguished using 9 TR markers. An MSP3α polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) using HhaI and AluI revealed 8 and 9 profiles, respectively, and 36 profiles when analyzed in combination. Combining TR and PCR-RFLP markers, 101 distinct molecular profiles were distinguished among these 110 patients. Nine TR markers arrayed along a 100 kB stretch of a P. vivax chromosome containing the gene for circumsporozoite protein showed non-linear linkage disequilibrium (ISA = 0.03, P = 0.001). These findings demonstrate the potential use of TR markers for molecular epidemiology studies. PMID:22492139

  20. Risk factors for HTLV-II infection in Peruvian men who have sex with men.

    PubMed

    Zunt, Joseph R; La Rosa, Alberto M; Peinado, Jesús; Lama, Javier R; Suarez, Luis; Pun, Monica; Cabezas, Cesar; Sanchez, Jorge

    2006-05-01

    Human T-cell lymphotropic virus type-II (HTLV-II) infection is endemic in indigenous groups in the Americas and injection drug users (IDUs) worldwide. In Peru, HTLV-II infection was previously identified in two indigenous Amazonians. We examined risk factors for HTLV-II infection in 2,703 Peruvian men who have sex with men (MSM): 35 (1.3%) were HTLV-II positive. HTLV-II infection was associated with syphilis, HSV-2 infection, unprotected receptive anal intercourse, and older age. This is the first report of HTLV-II in a non-indigenous non-IDU population in Peru. Additional studies are needed to determine if HTLV-II is a sexually transmitted infection in this and other sexually active populations.

  1. Distribution of Short-Term and Lifetime Predicted Risks of Cardiovascular Diseases in Peruvian Adults

    PubMed Central

    Quispe, Renato; Bazo-Alvarez, Juan Carlos; Burroughs Peña, Melissa S; Poterico, Julio A; Gilman, Robert H; Checkley, William; Bernabé-Ortiz, Antonio; Huffman, Mark D; Miranda, J Jaime

    2015-01-01

    Background Short-term risk assessment tools for prediction of cardiovascular disease events are widely recommended in clinical practice and are used largely for single time-point estimations; however, persons with low predicted short-term risk may have higher risks across longer time horizons. Methods and Results We estimated short-term and lifetime cardiovascular disease risk in a pooled population from 2 studies of Peruvian populations. Short-term risk was estimated using the atherosclerotic cardiovascular disease Pooled Cohort Risk Equations. Lifetime risk was evaluated using the algorithm derived from the Framingham Heart Study cohort. Using previously published thresholds, participants were classified into 3 categories: low short-term and low lifetime risk, low short-term and high lifetime risk, and high short-term predicted risk. We also compared the distribution of these risk profiles across educational level, wealth index, and place of residence. We included 2844 participants (50% men, mean age 55.9 years [SD 10.2 years]) in the analysis. Approximately 1 of every 3 participants (34% [95% CI 33 to 36]) had a high short-term estimated cardiovascular disease risk. Among those with a low short-term predicted risk, more than half (54% [95% CI 52 to 56]) had a high lifetime predicted risk. Short-term and lifetime predicted risks were higher for participants with lower versus higher wealth indexes and educational levels and for those living in urban versus rural areas (P<0.01). These results were consistent by sex. Conclusions These findings highlight potential shortcomings of using short-term risk tools for primary prevention strategies because a substantial proportion of Peruvian adults were classified as low short-term risk but high lifetime risk. Vulnerable adults, such as those from low socioeconomic status and those living in urban areas, may need greater attention regarding cardiovascular preventive strategies. PMID:26254303

  2. Patterns of geographic expansion of Aedes aegypti in the Peruvian Amazon.

    PubMed

    Guagliardo, Sarah Anne; Barboza, José Luis; Morrison, Amy C; Astete, Helvio; Vazquez-Prokopec, Gonzalo; Kitron, Uriel

    2014-08-01

    In the Peruvian Amazon, the dengue vector Aedes aegypti is abundant in large urban centers such as Iquitos. In recent years, it has also been found in a number of neighboring rural communities with similar climatic and socioeconomic conditions. To better understand Ae. aegypti spread, we compared characteristics of communities, houses, and containers in infested and uninfested communities. We conducted pupal-demographic surveys and deployed ovitraps in 34 communities surrounding the city of Iquitos. Communities surveyed were located along two transects: the Amazon River and a 95 km highway. We calculated entomological indices, mapped Ae. aegypti presence, and developed univariable and multivariable logistic regression models to predict Ae. aegypti presence at the community, household, or container level. Large communities closer to Iquitos were more likely to be infested with Ae. aegypti. Within infested communities, houses with Ae. aegypti had more passively-filled containers and were more often infested with other mosquito genera than houses without Ae. aegypti. For containers, large water tanks/drums and containers with solar exposure were more likely to be infested with Ae. aegypti. Maps of Ae. aegypti presence revealed a linear pattern of infestation along the highway, and a scattered pattern along the Amazon River. We also identified the geographical limit of Ae. aegypti expansion along the highway at 19.3 km south of Iquitos. In the Peruvian Amazon, Ae. aegypti geographic spread is driven by human transportation networks along rivers and highways. Our results suggest that urban development and oviposition site availability drive Ae. aegypti colonization along roads. Along rivers, boat traffic is likely to drive long-distance dispersal via unintentional transport of mosquitoes on boats.

  3. Eveningness Chronotype, Daytime Sleepiness, Caffeine Consumption, and Use of Other Stimulants Among Peruvian University Students

    PubMed Central

    Whittier, Anjalene; Sanchez, Sixto; Castañeda, Benjamín; Sanchez, Elena; Yanez, David; Williams, Michelle A.

    2014-01-01

    Objectives: The aims of this study were to evaluate patterns of circadian preferences and daytime sleepiness, and to examine the extent to which the consumption of stimulant beverages is associated with daytime sleepiness and evening chronotype among Peruvian college-age students. Methods: A total of 2,581 undergraduate students completed a self-administered comprehensive questionnaire that gathered information about sleep habits, sociodemographic and lifestyle characteristics, and the use of caffeinated beverages. The Morningness–Eveningness Questionnaire (MEQ) and Epworth Sleepiness Scale (ESS) were used to assess chronotype and daytime sleepiness. We used multivariable linear and logistic regression procedures to estimate odds ratios (OR) and 95% confidence intervals (95% CI) for the associations of sleep disorders with sociodemographic and behavioral factors. Results: The prevalence of daytime sleepiness was 35% [95% CI 32.7–36.4] and eveningness chronotype was 10% [95% CI 8.8–11.1%]. Age, sex, cigarette smoking, and alcohol consumption were significantly associated with an evening chronotype. After adjusting for age, sex, smoking, body mass index, and physical activity, students who reported consumption of any stimulant beverages had 1.25 increased odds of excessive daytime sleepiness (OR=1.25 [95% CI 1.03–1.53]) compared with students who did not consume stimulant beverages. Consumption of any stimulant beverages was not statistically significantly associated with being an evening chronotype (OR=1.30 [95% CI 0.86–1.96]). Conclusions: Excessive daytime sleepiness and eveningness chronotype are common among Peruvian college students. MEQ scores were associated with age, sex, smoking, and alcohol consumption. Regular stimulant beverage consumption tended to be positively associated with excessive daytime sleepiness. PMID:24868492

  4. Insight on the Peruvian Amazon River: A Planform Metric Characterization of its Morphodynamics

    NASA Astrophysics Data System (ADS)

    Garcia, A. M. P.; Ortals, C.; Frias, C. E.; Abad, J. D.; Vizcarra, J.

    2014-12-01

    Starting in Peru, the Amazon River flows through Colombia and Brazil; additionally, tributaries from Bolivia, Venezuela, and Ecuador contribute to the massive river and its unique geomorphic features. Accordingly, the Amazon Basin has become an important aspect of South America; it is an area of extraordinary biodiversity, rich resources, and unique cultures. However, due to the sheer magnitude and exceptionality of the Amazon River, research regarding the morphodynamic processes that shape and define the river has been difficult. Consequently, current research has not completely understood the planform dynamics of some portions of this river that present a main channel and secondary channels known as "anabranching structures". The purpose of this research was to gain an understanding of the geomorphology of the upper Amazon, the Peruvian section, by obtaining migration rates and planform metrics, including channel count, length, width, and sinuosity, as well as island count, area, and shape. With this data, the morphodynamics of the Peruvian Amazon, especially the relationship between the main channel and its secondary channels in each "anabranching structure" along the river, could be analyzed according to correlations found between various metrics. This analysis was carried out for 5-year time spans over a period of 25 years. Preliminary results showed that the average migration rate versus channel bend radius envelope peak is lower for the secondary channels than for the main channel. However, the maximum migration rate was not always found in the main channel; for several structures, the most dynamic channels were the secondary ones. This implies a certain periodicity to the river's migratory patterns that could be related to the valley boundaries, the local channel sinuosity or geological formations in the study area.

  5. Crustal structure of the Peruvian continental margin from wide-angle seismic studies

    NASA Astrophysics Data System (ADS)

    Krabbenhöft, A.; Bialas, J.; Kopp, H.; Kukowski, N.; Hübscher, C.

    2004-11-01

    Active seismic investigations along the Pacific margin off Peru were carried out using ocean bottom hydrophones and seismometers. The structure and the P-wave velocities of the obliquely subducting oceanic Nazca Plate and overriding South American Plate from 8°S to 15°S were determined by modelling the wide-angle seismic data combined with the analysis of reflection seismic data. Three detailed cross-sections of the subduction zone of the Peruvian margin and one strike-line across the Lima Basin are presented here. The oceanic crust of the Nazca Plate, with a thin pelagic sediment cover, ranging from 0-200 m, has an average thickness of 6.4 km. At 8°S it thins to 4 km in the area of Trujillo Trough, a graben-like structure. Across the margin, the plate boundary can be traced to 25 km depth. As inferred from the velocity models, a frontal prism exists adjacent to the trench axis and is associated with the steep lower slope. Terrigeneous sediments are proposed to be transported downslope due to gravitational forces and comprise the frontal prism, characterized by low seismic P-wave velocities. The lower slope material accretes against a backstop structure, which is defined by higher seismic P-wave velocities, 3.5-6.0 km s-1. The large variations in surface slope along one transect may reflect basal removal of upper plate material, thus steepening the slope surface. Subduction processes along the Peruvian margin are dominated by tectonic erosion indicated by the large margin taper, the shape and bending of the subducting slab, laterally varying slope angles and the material properties of the overriding continental plate. The erosional mechanisms, frontal and basal erosion, result in the steepening of the slope and consequent slope failure.

  6. Agreement Between Cardiovascular Disease Risk Scores in Resource-Limited Settings: Evidence from 5 Peruvian Sites.

    PubMed

    Bazo-Alvarez, Juan Carlos; Quispe, Renato; Peralta, Frank; Poterico, Julio A; Valle, Giancarlo A; Burroughs, Melissa; Pillay, Timesh; Gilman, Robert H; Checkley, William; Malaga, Germán; Smeeth, Liam; Bernabé-Ortiz, Antonio; Miranda, J Jaime

    2015-06-01

    It is unclear how well currently available risk scores predict cardiovascular disease (CVD) risk in low-income and middle-income countries. We aim to compare the American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort risk equations (ACC/AHA model) with 6 other CVD risk tools to assess the concordance of predicted CVD risk in a random sample from 5 geographically diverse Peruvian populations. We used data from 2 Peruvian, age and sex-matched, population-based studies across 5 geographical sites. The ACC/AHA model were compared with 6 other CVD risk prediction tools: laboratory Framingham risk score for CVD, non-laboratory Framingham risk score for CVD, Reynolds risk score, systematic coronary risk evaluation, World Health Organization risk charts, and the Lancet chronic diseases risk charts. Main outcome was in agreement with predicted CVD risk using Lin's concordance correlation coefficient. Two thousand one hundred and eighty-three subjects, mean age 54.3 (SD ± 5.6) years, were included in the analysis. Overall, we found poor agreement between different scores when compared with ACC/AHA model. When each of the risk scores was used with cut-offs specified in guidelines, ACC/AHA model depicted the highest proportion of people at high CVD risk predicted at 10 years, with a prevalence of 29.0% (95% confidence interval, 26.9-31.0%), whereas prevalence with World Health Organization risk charts was 0.6% (95% confidence interval, 0.2-8.6%). In conclusion, poor concordance between current CVD risk scores demonstrates the uncertainty of choosing any of them for public health and clinical interventions in Latin American populations. There is a need to improve the evidence base of risk scores for CVD in low-income and middle-income countries.

  7. Peruvian foothills, a key for future exploration in a frontier area

    SciTech Connect

    Villien, A.; Telles, A. Jr.

    1995-08-01

    Within the 1700 km Peruvian foothills, several units can be identified with different types of thrust belt geometry reflecting pre-Andean sedimentary history and structural framework. In the northern part, the Santiago area shows several {open_quote}en echelon{close_quotes} fault bounded folds separated from the main sub-Andean Maranon basin by an elongated thrusted arch. Locally, limited Late Tertiary inversion has preserved halokinetic structures initiated from Late Mesozoic to Early Tertiary. In the central part, the Huallaga area appears controlled by an inherited framework including NW-SE and ENE-WSW paleozoic trends. Furthermore Lower Mesozoic evaporates and associated deposits have acted as preferential decollement levels giving large hanging wall anticlines and several thrust slices at the leading edge. In the southern part, the Ene-Camisea-Madre de Dios area shows a major WNW-ESE trend intersected by NE-SW Paleozoic arches present in the Ucayali and Madre de Dios basins. Thrust belt geometry differs from basement involved structures to typical ramp-flat geometry with transverse features acting as transfer zones. Structure analysis reveals piggyback and overstep sequences of thrusting, and besides the classical late Miocene phase, a Plio-Pleistocene neotectonic event caused major uplift in the southern Peruvian foothills. Petroleum systems include several source rocks and reservoirs; nevertheless, parameters such as recent structural inversion may affect reservoir quality in the North. To the South, with Devonian, Carboniferous and Permian source rocks, some of them showing adequate maturity level for oil generation, precise knowledge of migration events and influence of recent uplift on frozen kitchens are key factors for exploration.

  8. Nitrogen fixation in sediments along a depth transect through the Peruvian oxygen minimum zone

    NASA Astrophysics Data System (ADS)

    Gier, J.; Sommer, S.; Löscher, C. R.; Dale, A. W.; Schmitz, R. A.; Treude, T.

    2015-09-01

    Benthic nitrogen (N2) fixation and sulfate reduction (SR) were investigated in the Peruvian oxygen minimum zone (OMZ). Sediment samples, retrieved by a multiple corer were taken at six stations (70-1025 m) along a depth transect at 12° S, covering anoxic and hypoxic bottom water conditions. Benthic N2 fixation was detected at all sites, with high rates measured in OMZ mid-waters between the 70 and 253 m and lowest N2 fixation rates below 253 m down to 1025 m water depth. SR rates were decreasing with increasing water depth, with highest rates at the shallow site. Benthic N2 fixation depth profiles largely overlapped with SR depth profiles, suggesting that both processes are coupled. The potential of N2 fixation by SR bacteria was verified by the molecular analysis of nifH genes. Detected nifH sequences clustered with SR bacteria that have been demonstrated to fix N2 in other benthic environments. Depth-integrated rates of N2 fixation and SR showed no direct correlation along the 12° S transect, suggesting that the benthic diazotrophs in the Peruvian OMZ are being controlled by additional various environmental factors. The organic matter availability and the presence of sulfide appear to be major drivers for benthic diazotrophy. It was further found that N2 fixation was not inhibited by high ammonium concentrations. N2 fixation rates in OMZ sediments were similar to rates measured in other organic-rich sediments. Overall, this work improves our knowledge on N sources in marine sediments and contributes to a better understanding of N cycling in OMZ sediments.

  9. Agreement Between Cardiovascular Disease Risk Scores in Resource-Limited Settings: Evidence from 5 Peruvian Sites

    PubMed Central

    Bazo-Alvarez, Juan Carlos; Quispe, Renato; Peralta, Frank; Poterico, Julio A.; Valle, Giancarlo A.; Burroughs, Melissa; Pillay, Timesh; Gilman, Robert H.; Checkley, William; Malaga, Germán; Smeeth, Liam; Bernabé-Ortiz, Antonio

    2015-01-01

    It is unclear how well currently available risk scores predict cardiovascular disease (CVD) risk in low-income and middle-income countries. We aim to compare the American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort risk equations (ACC/AHA model) with 6 other CVD risk tools to assess the concordance of predicted CVD risk in a random sample from 5 geographically diverse Peruvian populations. We used data from 2 Peruvian, age and sex-matched, population-based studies across 5 geographical sites. The ACC/AHA model were compared with 6 other CVD risk prediction tools: laboratory Framingham risk score for CVD, non-laboratory Framingham risk score for CVD, Reynolds risk score, systematic coronary risk evaluation, World Health Organization risk charts, and the Lancet chronic diseases risk charts. Main outcome was in agreement with predicted CVD risk using Lin’s concordance correlation coefficient. Two thousand one hundred and eighty-three subjects, mean age 54.3 (SD ± 5.6) years, were included in the analysis. Overall, we found poor agreement between different scores when compared with ACC/AHA model. When each of the risk scores was used with cut-offs specified in guidelines, ACC/AHA model depicted the highest proportion of people at high CVD risk predicted at 10 years, with a prevalence of 29.0% (95% confidence interval, 26.9–31.0%), whereas prevalence with World Health Organization risk charts was 0.6% (95% confidence interval, 0.2–8.6%). In conclusion, poor concordance between current CVD risk scores demonstrates the uncertainty of choosing any of them for public health and clinical interventions in Latin American populations. There is a need to improve the evidence base of risk scores for CVD in low-income and middle-income countries. PMID:26102017

  10. Whole-genome characterization of a Peruvian alpaca rotavirus isolate expressing a novel VP4 genotype.

    PubMed

    Rojas, Miguel; Gonçalves, Jorge Luiz S; Dias, Helver G; Manchego, Alberto; Pezo, Danilo; Santos, Norma

    2016-11-30

    The SA44 isolate of Rotavirus A (RVA) was identified from a neonatal Peruvian alpaca presenting with diarrhea, and the full-length genome sequence of the isolate (designated RVA/Alpaca-tc/PER/SA44/2014/G3P[40]) was determined. Phylogenetic analyses showed that the isolate possessed the genotype constellation G3-P[40]-I8-R3-C3-M3-A9-N3-T3-E3-H6, which differs considerably from those of RVA strains isolated from other species of the order Artiodactyla. Overall, the genetic constellation of the SA44 strain was quite similar to those of RVA strains isolated from a bat in Asia (MSLH14 and MYAS33). Nonetheless, phylogenetic analyses of each genome segment identified a distinct combination of genes. Several sequences were closely related to corresponding gene sequences in RVA strains from other species, including human (VP1, VP2, NSP1, and NSP2), simian (VP3 and NSP5), bat (VP6 and NSP4), and equine (NSP3). The VP7 gene sequence was closely related to RVA strains from a Peruvian alpaca (K'ayra/3368-10; 99.0% nucleotide and 99.7% amino acid identity) and from humans (RCH272; 95% nucleotide and 99.0% amino acid identity). The nucleotide sequence of the VP4 gene was distantly related to other VP4 sequences and was designated as the reference strain for the new P[40] genotype. This unique genetic makeup suggests that the SA44 strain emerged from multiple reassortment events between bat-, equine-, and human-like RVA strains. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Cost-effectiveness analysis of pneumococcal conjugate vaccines in preventing pneumonia in Peruvian children.

    PubMed

    Mezones-Holguín, Edward; Bolaños-Díaz, Rafael; Fiestas, Víctor; Sanabria, César; Gutiérrez-Aguado, Alfonso; Fiestas, Fabián; Suárez, Víctor J; Rodriguez-Morales, Alfonso J; Hernández, Adrián V

    2014-12-15

    Pneumococcal pneumonia (PP) has a high burden of morbimortality in children. Use of pneumococcal conjugate vaccines (PCVs) is an effective preventive measure. After PCV 7-valent (PCV7) withdrawal, PCV 10-valent (PCV10) and PCV 13-valent (PCV13) are the alternatives in Peru. This study aimed to evaluate cost effectiveness of these vaccines in preventing PP in Peruvian children <5 years-old. A cost-effectiveness analysis was developed in three phases: a systematic evidence search for calculating effectiveness; a cost analysis for vaccine strategies and outcome management; and an economic model based on decision tree analysis, including deterministic and probabilistic sensitivity analysis using acceptability curves, tornado diagram, and Monte Carlo simulation. A hypothetic 100 vaccinated children/vaccine cohort was built. An incremental cost-effectiveness ratio (ICER) was calculated. The isolation probability for all serotypes in each vaccine was estimated: 38% for PCV7, 41% PCV10, and 17% PCV13. Avoided hospitalization was found to be the best effectiveness model measure. Estimated costs for PCV7, PCV10, and PCV13 cohorts were USD13,761, 11,895, and 12,499, respectively. Costs per avoided hospitalization were USD718 for PCV7, USD333 for PCV10, and USD 162 for PCV13. At ICER, PCV7 was dominated by the other PCVs. Eliminating PCV7, PCV13 was more cost effective than PCV10 (confirmed in sensitivity analysis). PCV10 and PCV13 are more cost effective than PCV7 in prevention of pneumonia in children <5 years-old in Peru. PCV13 prevents more hospitalizations and is more cost-effective than PCV10. These results should be considered when making decisions about the Peruvian National Inmunizations Schedule.

  12. Trauma exposure and post-traumatic stress disorder in a cohort of pregnant Peruvian women.

    PubMed

    Levey, Elizabeth J; Gelaye, Bizu; Koenen, Karestan; Zhong, Qiu-Yue; Basu, Archana; Rondon, Marta B; Sanchez, Sixto; Henderson, David C; Williams, Michelle A

    2017-09-13

    Women have a higher prevalence of post-traumatic stress disorder (PTSD) than men, with a peak during the reproductive years. PTSD during pregnancy adversely impacts maternal and infant health outcomes. The objectives of this study were to estimate the prevalence of antepartum PTSD symptoms in a population of pregnant Peruvian women and to examine the impact of number of traumatic events and type of trauma experienced. The Traumatic Events Questionnaire was used to collect data about traumatic exposures. The Post-traumatic Stress Disorder Checklist-Civilian Version (PCL-C) was used to assess PTSD. Multivariable logistic regression procedures were used to estimate adjusted odds ratios (aOR) and 95% confidence intervals (95% CI). Three thousand three hundred seventy-two pregnant women were interviewed. Of the 2920 who reported experiencing one or more traumatic events, 41.8% met criteria for PTSD (PCL-C score ≥ 26). A quarter of participants had experienced four or more traumas, and 60.5% of those women had PTSD. Interpersonal trauma was most strongly associated with PTSD (aOR, 3.20; 95% CI, 2.74-3.74), followed by unspeakable trauma (aOR, 2.87; 95% CI, 2.35-3.50), and structural trauma (aOR, 1.39; 95% CI, 1.15-1.67). These findings indicate the high prevalence of PTSD during pregnancy in the Peruvian population, which is relevant to other countries suffering from terrorism, war, or high rates of violence. This underscores the importance of screening for PTSD in pregnancy.

  13. Prevalence of metabolic syndrome and its relationship with leisure time physical activity among Peruvian adults

    PubMed Central

    Gelaye, Bizu; Tafur, Luis Revilla; Lopez, Tania; Sanchez, Sixto; Williams, Michelle A.

    2009-01-01

    Background Metabolic syndrome (MetS) is an important risk factor of cardiovascular disease (CVD) and type 2 diabetes (T2DM). Previous studies have suggested an inverse relationship between physical activity and MetS. However, these findings were inconsistent; and few investigators have examined these associations among South Americans. We estimated the prevalence of MetS and its association with leisure time physical activity (LTPA) among Peruvian adults. Materials and methods This cross-sectional study of 1,675 individuals (619 men and 1056 women) was conducted among residents in Lima and Callao, Peru. Information about LTPA, socio-demographic, and other lifestyle characteristics were collected by interview. The presence of MetS was defined using the Adult Treatment Panel III (ATP III) criteria. Results Overall, the prevalence of MetS was 26.9% and was more common among women (29.9%) than men (21.6%). Habitual participation in LTPA was associated with a 23% reduced risk of MetS (OR=0.77; 95% CI: 0.60–1.03). There was an inverse trend of MetS risk with amount of LTPA (p=0.016). Compared with non-exercisers, those who exercised < 150 minutes/week had a 21% reduced risk of MetS (AOR= 0.79; 95% CI 0.60–1.04). Individuals who exercised ≥ 150 minutes/week, compared with non-exercisers, had a 42% reduced risk of MetS (AOR=0.58; 95% CI: 0.36–0.93). Associations of similar magnitudes were observed when men and women were studied separately. Conclusion These data document a high prevalence of MetS and suggest an association with LTPA among urban dwelling Peruvians. Further prospective studies are needed to confirm these observations and to examine interventions that may promote increased physical activity in this population. PMID:19563445

  14. Patterns of Geographic Expansion of Aedes aegypti in the Peruvian Amazon

    PubMed Central

    Guagliardo, Sarah Anne; Barboza, José Luis; Morrison, Amy C.; Astete, Helvio; Vazquez-Prokopec, Gonzalo; Kitron, Uriel

    2014-01-01

    Background and Objectives In the Peruvian Amazon, the dengue vector Aedes aegypti is abundant in large urban centers such as Iquitos. In recent years, it has also been found in a number of neighboring rural communities with similar climatic and socioeconomic conditions. To better understand Ae. aegypti spread, we compared characteristics of communities, houses, and containers in infested and uninfested communities. Methods We conducted pupal-demographic surveys and deployed ovitraps in 34 communities surrounding the city of Iquitos. Communities surveyed were located along two transects: the Amazon River and a 95km highway. We calculated entomological indices, mapped Ae. aegypti presence, and developed univariable and multivariable logistic regression models to predict Ae. aegypti presence at the community, household, or container level. Results Large communities closer to Iquitos were more likely to be infested with Ae. aegypti. Within infested communities, houses with Ae. aegypti had more passively-filled containers and were more often infested with other mosquito genera than houses without Ae. aegypti. For containers, large water tanks/drums and containers with solar exposure were more likely to be infested with Ae. aegypti. Maps of Ae. aegypti presence revealed a linear pattern of infestation along the highway, and a scattered pattern along the Amazon River. We also identified the geographical limit of Ae. aegypti expansion along the highway at 19.3 km south of Iquitos. Conclusion In the Peruvian Amazon, Ae. aegypti geographic spread is driven by human transportation networks along rivers and highways. Our results suggest that urban development and oviposition site availability drive Ae. aegypti colonization along roads. Along rivers, boat traffic is likely to drive long-distance dispersal via unintentional transport of mosquitoes on boats. PMID:25101786

  15. The Relationship Between Socioeconomic Status and CV Risk Factors: The CRONICAS Cohort Study of Peruvian Adults.

    PubMed

    Quispe, Renato; Benziger, Catherine P; Bazo-Alvarez, Juan Carlos; Howe, Laura D; Checkley, William; Gilman, Robert H; Smeeth, Liam; Bernabé-Ortiz, Antonio; Miranda, J Jaime

    2016-03-01

    Variations in the distribution of cardiovascular disease and risk factors by socioeconomic status (SES) have been described in affluent societies, yet a better understanding of these patterns is needed for most low- and middle-income countries. This study sought to describe the relationship between cardiovascular risk factors and SES using monthly family income, educational attainment, and assets index, in 4 Peruvian sites. Baseline data from an age- and sex-stratified random sample of participants, ages ≥35 years, from 4 Peruvian sites (CRONICAS Cohort Study, 2010) were used. The SES indicators considered were monthly family income (n = 3,220), educational attainment (n = 3,598), and assets index (n = 3,601). Behavioral risk factors included current tobacco use, alcohol drinking, physical activity, daily intake of fruits and vegetables, and no control of salt intake. Cardiometabolic risk factors included obesity, elevated waist circumference, hypertension, insulin resistance, diabetes mellitus, low high-density lipoprotein cholesterol, and high triglyceride levels. In the overall population, 41.6% reported a monthly family income

  16. Prevalence of sarcopenia and associated factors in the healthy older adults of the Peruvian Andes.

    PubMed

    Tramontano, Alessandra; Veronese, Nicola; Sergi, Giuseppe; Manzato, Enzo; Rodriguez-Hurtado, Diana; Maggi, Stefania; Trevisan, Caterina; De Zaiacomo, Francesca; Giantin, Valter

    To assess the prevalence of sarcopenia and associated factors in a population of older people living in a rural area of the Peruvian Andes. The study concerned 222 people aged ≥65 years. Sarcopenia was diagnosed on the basis of skeletal muscle mass, measured using bioimpedance analysis, and gait speed, measured with the 4-m walking test, as recommended by the International Working Group on sarcopenia. Self-reported physical activity, the Short Physical Performance Battery, and the Six-Minute Walking Test also contributed information on participants' physical performance status. Disabilities were investigated by assessing participants' self-reported difficulties in performing one or more basic or instrumental activities of daily living. The prevalence of sarcopenia was 17.6%. Compared with participants without sarcopenia, individuals who were found sarcopenic were significantly older, female and were less frequently farmers, had fewer children, had a worse nutritional status, a significantly lower physical performance, and higher levels of disability in the instrumental activities of daily living. After adjusting for potential confounders, age, female sex, a low body mass index, a self-reported low physical activity level, a worse Six-Minute Walking Test scores, and a low number of children were significantly associated with sarcopenia. The prevalence of sarcopenia seems to be quite high among community-dwelling older subjects in the Peruvian Andes. Age, female sex, a low body mass index, little physical activity, a poor Six-Minute Walking Test scores, and a low number of children could be associated with this condition. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  17. Biogenic halocarbons from the Peruvian upwelling region as tropospheric halogen source

    NASA Astrophysics Data System (ADS)

    Hepach, Helmke; Quack, Birgit; Tegtmeier, Susann; Engel, Anja; Bracher, Astrid; Fuhlbrügge, Steffen; Galgani, Luisa; Atlas, Elliot L.; Lampel, Johannes; Frieß, Udo; Krüger, Kirstin

    2016-09-01

    Halocarbons are produced naturally in the oceans by biological and chemical processes. They are emitted from surface seawater into the atmosphere, where they take part in numerous chemical processes such as ozone destruction and the oxidation of mercury and dimethyl sulfide. Here we present oceanic and atmospheric halocarbon data for the Peruvian upwelling zone obtained during the M91 cruise onboard the research vessel METEOR in December 2012. Surface waters during the cruise were characterized by moderate concentrations of bromoform (CHBr3) and dibromomethane (CH2Br2) correlating with diatom biomass derived from marker pigment concentrations, which suggests this phytoplankton group is a likely source. Concentrations measured for the iodinated compounds methyl iodide (CH3I) of up to 35.4 pmol L-1, chloroiodomethane (CH2ClI) of up to 58.1 pmol L-1 and diiodomethane (CH2I2) of up to 32.4 pmol L-1 in water samples were much higher than previously reported for the tropical Atlantic upwelling systems. Iodocarbons also correlated with the diatom biomass and even more significantly with dissolved organic matter (DOM) components measured in the surface water. Our results suggest a biological source of these compounds as a significant driving factor for the observed large iodocarbon concentrations. Elevated atmospheric mixing ratios of CH3I (up to 3.2 ppt), CH2ClI (up to 2.5 ppt) and CH2I2 (3.3 ppt) above the upwelling were correlated with seawater concentrations and high sea-to-air fluxes. During the first part of the cruise, the enhanced iodocarbon production in the Peruvian upwelling contributed significantly to tropospheric iodine levels, while this contribution was considerably smaller during the second part.

  18. Eveningness Chronotype, Daytime Sleepiness, Caffeine Consumption, and Use of Other Stimulants Among Peruvian University Students.

    PubMed

    Whittier, Anjalene; Sanchez, Sixto; Castañeda, Benjamín; Sanchez, Elena; Gelaye, Bizu; Yanez, David; Williams, Michelle A

    2014-03-01

    Objectives: The aims of this study were to evaluate patterns of circadian preferences and daytime sleepiness, and to examine the extent to which the consumption of stimulant beverages is associated with daytime sleepiness and evening chronotype among Peruvian college-age students. Methods: A total of 2,581 undergraduate students completed a self-administered comprehensive questionnaire that gathered information about sleep habits, sociodemographic and lifestyle characteristics, and the use of caffeinated beverages. The Morningness-Eveningness Questionnaire (MEQ) and Epworth Sleepiness Scale (ESS) were used to assess chronotype and daytime sleepiness. We used multivariable linear and logistic regression procedures to estimate odds ratios (OR) and 95% confidence intervals (95% CI) for the associations of sleep disorders with sociodemographic and behavioral factors. Results: The prevalence of daytime sleepiness was 35% [95% CI 32.7-36.4] and eveningness chronotype was 10% [95% CI 8.8-11.1%]. Age, sex, cigarette smoking, and alcohol consumption were significantly associated with an evening chronotype. After adjusting for age, sex, smoking, body mass index, and physical activity, students who reported consumption of any stimulant beverages had 1.25 increased odds of excessive daytime sleepiness (OR=1.25 [95% CI 1.03-1.53]) compared with students who did not consume stimulant beverages. Consumption of any stimulant beverages was not statistically significantly associated with being an evening chronotype (OR=1.30 [95% CI 0.86-1.96]). Conclusions: Excessive daytime sleepiness and eveningness chronotype are common among Peruvian college students. MEQ scores were associated with age, sex, smoking, and alcohol consumption. Regular stimulant beverage consumption tended to be positively associated with excessive daytime sleepiness.

  19. Association Between Plasma N-Acylethanolamides and High Hemoglobin Concentration in Southern Peruvian Highlanders.

    PubMed

    Alarcón-Yaquetto, Dulce E; Caballero, Lidia; Gonzales, Gustavo F

    2017-06-30

    Alarcón-Yaquetto, Dulce E., Lidia Caballero, and Gustavo F. Gonzales. Association between plasma N-acylethanolamides and high hemoglobin concentration in Southern Peruvian highlanders. High Alt Med Biol 00:000-000, 2017.-High-altitude (HA) hypoxia is a stressful condition endured by organisms through different mechanisms. Failing to adapt to chronic HA exposure leads to a disease called chronic mountain sickness (CMS) characterized by excessive erythrocytosis (hemoglobin [Hb] ≥19 g/dL for women and ≥21 g/dL for men). Genes encoding for peroxisome proliferator-activated receptor (PPAR) subunits α and γ have been proposed as candidate genes for HA adaptation. N-acylethanolamides (NAEs) are endogenous fatty acid substances that bind to PPAR-α and -γ. NAEs are also able to modulate the endocannabinoid system, a signaling pathway activated in physiological stressful conditions. In the frame of a metabolomic study, we measured plasma levels of four NAEs: palmitoylethanolamide (PEA), oleoylethanolamide (OEA), stearoyl ethanolamide (SEA), and linoleoyl ethanolamide (LEA) in natives from Puno (3830 m), a city located in the Peruvian Southern Andes, and Lima (150 m). All NAEs were significantly higher in the HA population (p < 0.001, q < 0.001). Subjects with higher NAE values were those with higher Hb concentration and lower pulse oxygen saturation. However, there was no association between NAEs and CMS score. Our results suggest that PEA and OEA could be involved in physiological regulation following long-term HA exposure.

  20. Pharmacokinetics of Rifampin in Peruvian Tuberculosis Patients with and without Comorbid Diabetes or HIV

    PubMed Central

    Davies, Geraint; Ardrey, Alison; Jave, Oswaldo; López-Romero, Sonia L.; Ward, Stephen A.; Moore, David A. J.

    2012-01-01

    For drug-compliant patients, poor responses to tuberculosis (TB) treatment might be attributable to subtherapeutic drug concentrations. An impaired absorption of rifampin was previously reported for patients with diabetes mellitus (DM) or HIV. The objectives of this study were to determine whether TB drug pharmacokinetics differed in Peruvian TB patients with DM or HIV. In this cross-sectional study, TB patients, recruited from health centers in Lima, Peru, had blood samples taken at 2 and 6 h after directly observed TB drug ingestion, to determine plasma concentrations of rifampin. Of 105 patients, 50 had TB without a comorbidity, 26 had coexistent DM, and 29 had coexistent HIV. Unexpectedly, the overall median 2- and 6-h levels of rifampin were 1.6 and 3.2 mg/liter, respectively, and the time to the peak concentration was 6 h (slow absorber) instead of 2 h (fast absorber) for 61 patients (62.2%). The geometric mean peak concentration of drug in serum (Cmax) was significantly higher in fast absorbers than in slow absorbers (5.0 versus 3.8 mg/liter; P = 0.05). The rifampin Cmax was significantly lower in male patients than in female patients (3.3 versus 6.3 mg/liter; P < 0.001). Neither slow nor fast absorbers with comorbidities (DM or HIV) had significantly different Cmax results compared to those of TB patients without comorbidities. An analysis of variance regression analysis showed that female gender (P < 0.001) and the time to maximum concentration of drug in serum (Tmax) at 2 h (P = 0.012) were independently correlated with increased exposure to rifampin. Most of this Peruvian study population exhibited rifampin pharmacokinetics different from those conventionally reported, with delayed absorption and low plasma concentrations, independent of the presence of an HIV or DM comorbidity. PMID:22330931

  1. An Analysis of SST Gradients off the Peruvian Coast: The impact of going to higher resolution

    NASA Astrophysics Data System (ADS)

    Vazquez, J.; Dewitte, B.; Chin, T. M.; Armstrong, E. M.; Purca, S.; Alburqueque, E.

    2013-05-01

    The Peruvian Coastal Upwelling System (PCUS) is one of the most productive fisheries in the world. Upwelling events are associated with changes in the magnitude and location of frontal structures. SST gradients from four different data sets, NCDC, REMSS, OSTIA, and MUR are compared in two test areas off the PCUS: Païta (5°S) and Pisco (14°S). In both areas SST gradients derived from the MUR data set show greater magnitudes, as well as larger seasonal cycles. Off Pisco, the magnitude of the seasonal cycle of 2.2°C/100km in MUR is larger than the one derived from the lower resolution data sets. All data sets at Pisco exhibit a seasonal cycle that peaks in late Austral summer and early fall. Hovmuller diagrams calculated at 5.5°S, 10.5°S, and 14.5°S show clearly defined offshore maxima in the cross-shore gradients for all the data sets. Upwelling scales determined by the distance to the first maxima vary depending on the data set used. At 5.5°S upwelling scales vary from 10km for MUR to 50km for NCDC. At 14.5°S the scales vary from 20km for MUR to 40km for OSTIA. All four date sets show similar large-scale structures associated with the Peruvian Upwelling. However MUR shows finer scale structure that are most likely due to submesoscale to mesoscale eddies. Sub-sampled MUR 1km data at the 25km, 9km, and 4km resolutions compare well in magnitude and phase with the lower resolution products. Agreement in gradient magnitude between the lower resolution data sets and the MUR sub-subsampled at their respective resolutions imply that the pixel-to-pixel analysis noise in MUR is at a similar level as the other data sets.t;

  2. Psychometric Properties of the Pittsburgh Sleep Quality Index (PSQI) in a Cohort of Peruvian Pregnant Women.

    PubMed

    Zhong, Qiu-Yue; Gelaye, Bizu; Sánchez, Sixto E; Williams, Michelle A

    2015-08-15

    We sought to evaluate the construct validity and factor structure of the Spanish-language version of the Pittsburgh Sleep Quality Index (PSQI) among pregnant Peruvian women. A cohort of 642 women were interviewed at ≤ 16 weeks of gestation. During interview, we ascertained information about lifestyles, demographics, sleep characteristics, and mood symptoms. Stress induced sleep disturbance, depressive symptoms, and anxiety symptoms were evaluated using the Ford Insomnia Response to Stress Test (FIRST), Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder-7 (GAD-7) assessment scales, respectively. Consistency indices, exploratory and confirmatory factor analyses, correlations, and logistic regressions were used. Both exploratory and confirmatory factor analyses indicated a three-factor solution: sleep quality, sleep efficiency, and sleep medication. We observed significantly positive correlations of the PSQI with the FIRST (0.42), the PHQ-9 (0.49), and the GAD-7 (0.46). Poor sleepers (PSQI global score > 5) had significantly increased odds of experiencing stress-induced sleep disturbance (odds ratio, OR = 3.57; 95% CI: 2.40, 5.31), depression (OR = 5.48; 95% CI: 3.58, 8.37), and generalized anxiety disorder (OR = 4.57; 95% CI: 3.08, 6.76). The Spanish-language version of the PSQI instrument was found to have good construct validity among pregnant Peruvian women. Consistent with some other studies, the PSQI was found to have a three-factor structure. Further assessment and validation studies are needed to determine whether the three, factor-specific scoring of the PSQI is favored over the PSQI global score in diverse populations. © 2015 American Academy of Sleep Medicine.

  3. Family Impact Scale (FIS): Cross-cultural Adaptation and Psychometric Properties for the Peruvian Spanish Language.

    PubMed

    Abanto, Jenny; Albites, Ursula; Bönecker, Marcelo; Paiva, Saul M; Castillo, Jorge L; Aguilar-Gálvez, Denisse

    2015-12-01

    The lack of a Family Impact Scale (FIS) in Spanish language limits its use as an indicator in Spanish-speaking countries and precludes comparisons with data from other cultural and ethnic groups. The purpose of this study was therefore to adapt the FIS cross-culturally to the Peruvian Spanish language and assess its reliability and validity. In order to translate and adapt the FIS cross-culturally, it was answered by 60 parents in two pilot tests, after which it was tested on 200 parents of children aged 11 to 14 years who were clinically examined for dental caries experience and malocclusions. Internal consistency was assessed by Cronbach's alpha coefficient while repeat administration of the FIS on the same 200 parents enabled the test-retest reliability to be assessed via intraclass correlation coefficient (ICC). Construct and discriminant validity were based on associations of the FIS with global ratings of oral health and clinical groups, respectively. Mean (standard deviation) FIS total score was 5.20 (5.86). Internal consistency was confirmed by Cronbach's alpha 0.84. Test-retest reliability revealed excellent reproducibility (ICC = 0.96). Construct validity was good, demonstrating statistically significant associations between total FIS score and global ratings of oral health (p=0.007) and overall wellbeing (p=0.002), as well as for the subscale scores (p<0.05) with exception of the financial burden subscale. The FIS was also able to discriminate between children with and without dental caries experience and malocclusions (p<0.05). Satisfactory psychometric results for the Peruvian Spanish FIS confirm it as a reliable, valid instrument for assessing the impact on the family caused by children's oral conditions.

  4. Phylogenetic relationships of Shiga toxin-producing Escherichia coli isolated from Peruvian children

    PubMed Central

    Contreras, C. A.; Ruiz, J.; Lacher, D. W.; Rivera, F. P.; Saenz, Y.; Chea-Woo, E.; Zavaleta, N.; Gil, A. I.; Lanata, C. F.; Huicho, L.; Maves, R. C.; Torres, C.; DebRoy, C.; Cleary, T. G.

    2011-01-01

    The aim of this study was to determine the prevalence, virulence factors (stx, eae, ehxA and astA) and phylogenetic relationships [PFGE and multilocus sequence typing (MLST)] of Shiga toxin-producing Escherichia coli (STEC) strains isolated from four previous cohort studies in 2212 Peruvian children aged <36 months. STEC prevalence was 0.4 % (14/3219) in diarrhoeal and 0.6 % (15/2695) in control samples. None of the infected children developed haemolytic uraemic syndrome (HUS) or other complications of STEC. stx1 was present in 83 % of strains, stx2 in 17 %, eae in 72 %, ehxA in 59 % and astA in 14 %. The most common serotype was O26 : H11 (14 %) and the most common seropathotype was B (45 %). The strains belonged mainly to phylogenetic group B1 (52 %). The distinct combinations of alleles across the seven MLST loci were used to define 13 sequence types among 19 STEC strains. PFGE typing of 20 STEC strains resulted in 19 pulsed-field patterns. Comparison of the patterns revealed 11 clusters (I–XI), each usually including strains belonging to different serotypes; one exception was cluster VI, which gathered exclusively seven strains of seropathotype B, clonal group enterohaemorrhagic E. coli (EHEC) 2 and phylogenetic group B1. In summary, STEC prevalence was low in Peruvian children with diarrhoea in the community setting. The strains were phylogenetically diverse and associated with mild infections. However, additional studies are needed in children with bloody diarrhoea and HUS. PMID:21292859

  5. Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry.

    PubMed

    Zamudio, Roxana; Pereira, Latife; Rocha, Carolina D; Berg, Douglas E; Muniz-Queiroz, Thaís; Sant Anna, Hanaisa P; Cabrera, Lilia; Combe, Juan M; Herrera, Phabiola; Jahuira, Martha H; Leão, Felipe B; Lyon, Fernanda; Prado, William A; Rodrigues, Maíra R; Rodrigues-Soares, Fernanda; Santolalla, Meddly L; Zolini, Camila; Silva, Aristóbolo M; Gilman, Robert H; Tarazona-Santos, Eduardo; Kehdy, Fernanda S G

    2016-01-01

    Gastric adenocarcinoma is associated with chronic infection by Helicobacter pylori and with the host inflammatory response triggered by it, with substantial inter-person variation in the immune response profile due to host genetic factors. To investigate the diversity of the proinflammatory genes IL8, its receptors and PTGS2 in Amerindians; to test whether candidate SNPs in these genes are associated with gastric cancer in an admixed population with high Amerindian ancestry from Lima, Peru; and to assess whether an IL8RB promoter-derived haplotype affects gene expression. We performed a Sanger-resequencing population survey, a candidate-gene association study (220 cases, 288 controls) and meta-analyses. We also performed an in vitro validation by a reporter gene assay of IL8RB promoter. The diversity of the promoter of studied genes in Native Americans is similar to Europeans. Although an association between candidate SNPs and gastric cancer was not found in Peruvians, trend in our data is consistent with meta-analyses results that suggest PTGS2-rs689466-A is associated with H. pylori-associated gastric cancer in East Asia. IL8RB promoter-derived haplotype (rs3890158-A/rs4674258-T), common in Peruvians, was up-regulated by TNF-α unlike the ancestral haplotype (rs3890158-G/rs4674258-C). Bioinformatics analysis suggests that this effect stemmed from creation of a binding site for the FOXO3 transcription factor by rs3890158G>A. Our updated meta-analysis reinforces the role of PTGS2-rs689466-A in gastric cancer in Asians, although more studies that control for ancestry are necessary to clarify its role in Latin Americans. Finally, we suggest that IL8RB-rs3890158G>A is a cis-regulatory SNP.

  6. Persistence of growth stunting in a Peruvian high altitude community, 1964-1999.

    PubMed

    Pawson, Ivan G; Huicho, Luis

    2010-01-01

    The growth of children living in Nuñoa, a Peruvian high-altitude community, was studied over a 35-year period using data collected in 1964 and 1999. There had been evidence of a secular trend in growth in the mid-1980s, but this was before a period of sociopolitical upheaval lasting until the late 1990s partly linked to the activities of the Shining Path group and the Peruvian government's response. Anthropometric data for 576 children examined in 1964-1966 were compared with data from 361 children examined in 1999. Data were converted to Z Scores using NCHS/WHO reference standards. Compared with the 1964 cohort, boys in 1999 had marginally greater height Z Scores, but among females, the trend was reversed. Stunting prevalence had decreased from 1964 levels, but still approached 60% in both sexes, among the highest rates recorded for a modern world population. The prevalence of low weight for height was less than expected, possibly because of the compensatory effect of enlarged chest diameter. This anatomical feature may represent the effect of chronic hypoxic stress, causing growth of the chest cavity at the expense of growth in height. In view of modest improvements during the late 1980s in this population, we believe that the relatively poor growth status of children a decade later may result from food disruption associated with later political instability. Compared with children in a nearby community, which benefits from the socioeconomic infrastructure associated with a large copper mine, Nuñoa children continue to fare relatively poorly.

  7. Organic Matter Analysis of the Hyper-Arid Peruvian Desert in comparison to other Hyper-Arid Environments

    NASA Astrophysics Data System (ADS)

    Valdivia-Silva, J. E.; Fletcher, L. E.; Navarro-González, R.; McKay, C. P.; Pérez Montano, S.; Condori Apaza, R.; Conley, C. A.

    2005-12-01

    The Peruvian Desert is located along the Pacific coast of southern Peru and is a continuation of the Atacama Desert in Chile. The Peruvian Desert at the Pampas of La Joya has extreme environmental conditions, such as hyperaridity, and a complete absence of macroscopic life. La Joya contains volcanic soils with the presence of magnetite and quartz. Furthermore, the El Niño phenomena, centralized directly off the coast-line near La Joya, provides stronger climactic effects on this desert, resulting in higher levels of precipitation which should allow for the development of microscopic life. Taking into account that life is based on carbon, here we search for relationships between soil organic matter detected by oxidation versus pyrolisis (pyr-GC-MS) techniques. Our preliminary results showed similar levels of organic compounds to Yungay, the hyper-arid core of the Atacama Desert, similar levels of organic compounds to the Antarctic Dry Valleys, and direct correlation between oxidation and pyrolitic techniques.

  8. A 22,000 year record of changing redox conditions from the Peruvian Oxygen Minimum Zone (OMZ): benthic foraminifera approach

    NASA Astrophysics Data System (ADS)

    Erdem, Z.; Schönfeld, J.; Glock, N.

    2015-12-01

    Benthic foraminifera have been used as proxies for the prevailing conditions at the sediment-water interface. Their distribution patterns are thought to facilitate reconstruction of past environmental conditions. Variations of bottom water oxygenation can be traced by the downcore distribution of benthic foraminifera and some of their morphological characters. Being one of the strongest and most pronounced OMZs in today's world oceans, the Peruvian OMZ is a key area to study such variations in relation with changing climate. Spatial changes or an extension of the OMZ through time and space are investigated using sediment cores from the lower OMZ boundary. We focus on time intervals Late Holocene, Early Holocene, Bølling Allerød, Heinrich-Stadial 1 and Last Glacial Maximum (LGM) to investigate changes in bottom-water oxygen and redox conditions. The recent distributions of benthic foraminiferal assemblages provide background data for an interpretation of the past conditions. Living benthic foraminiferal faunas from the Peruvian margin are structured with the prevailing bottom-water oxygen concentrations today (Mallon et al., 2012). Downcore distribution of benthic foraminiferal assemblages showed fluctuations in the abundance of the indicator species depicting variations and a decreasing trend in bottom water oxygen conditions since the LGM. In addition, changes in bottom-water oxygen and nitrate concentrations are reconstructed for the same time intervals by the pore density in tests of Planulina limbata and Bolivina spissa (Glock et al., 2011), respectively. The pore densities also indicate a trend of higher oxygen and nitrate concentrations in the LGM compared to the Holocene. Combination of both proxies provide information on past bottom-water conditions and changes of oxygen concentrations for the Peruvian margin. Glock et al., 2011: Environmental influences on the pore density of Bolivina spissa (Cushman), Journal of Foraminiferal Research, v. 41, no. 1, p

  9. Can legality verification enhace local rights to forest resources? Piloting the policy learning protocol in the Peruvian forest context

    Treesearch

    B. Cashore; I. Visseren-Hamakers; P. Caro Torres; W. de Jong; A. Denvir; D. Humphreys; Kathleen McGinley; G. Auld; S. Lupberger; C. McDermott; S. Sax; D. Yin

    2016-01-01

    This report, “Can Legality Verification Enhance Local Rights to Forest Resources? Piloting the policy learning protocol in the Peruvian forest context,” reports on the testing of the application of the 11-step Policy Learning Protocol in Peru in 2015-16. The Protocol (Cashore et al. 2014) enables actors to draw from international policy initiatives in order to improve...

  10. Coupled ecosystem/supply chain modelling of fish products from sea to shelf: the Peruvian anchoveta case.

    PubMed

    Avadí, Angel; Fréon, Pierre; Tam, Jorge

    2014-01-01

    Sustainability assessment of food supply chains is relevant for global sustainable development. A framework is proposed for analysing fishfood (fish products for direct human consumption) supply chains with local or international scopes. It combines a material flow model (including an ecosystem dimension) of the supply chains, calculation of sustainability indicators (environmental, socio-economic, nutritional), and finally multi-criteria comparison of alternative supply chains (e.g. fates of landed fish) and future exploitation scenarios. The Peruvian anchoveta fishery is the starting point for various local and global supply chains, especially via reduction of anchoveta into fishmeal and oil, used worldwide as a key input in livestock and fish feeds. The Peruvian anchoveta supply chains are described, and the proposed methodology is used to model them. Three scenarios were explored: status quo of fish exploitation (Scenario 1), increase in anchoveta landings for food (Scenario 2), and radical decrease in total anchoveta landings to allow other fish stocks to prosper (Scenario 3). It was found that Scenario 2 provided the best balance of sustainability improvements among the three scenarios, but further refinement of the assessment is recommended. In the long term, the best opportunities for improving the environmental and socio-economic performance of Peruvian fisheries are related to sustainability-improving management and policy changes affecting the reduction industry. Our approach provides the tools and quantitative results to identify these best improvement opportunities.

  11. Coupled Ecosystem/Supply Chain Modelling of Fish Products from Sea to Shelf: The Peruvian Anchoveta Case

    PubMed Central

    Avadí, Angel; Fréon, Pierre; Tam, Jorge

    2014-01-01

    Sustainability assessment of food supply chains is relevant for global sustainable development. A framework is proposed for analysing fishfood (fish products for direct human consumption) supply chains with local or international scopes. It combines a material flow model (including an ecosystem dimension) of the supply chains, calculation of sustainability indicators (environmental, socio-economic, nutritional), and finally multi-criteria comparison of alternative supply chains (e.g. fates of landed fish) and future exploitation scenarios. The Peruvian anchoveta fishery is the starting point for various local and global supply chains, especially via reduction of anchoveta into fishmeal and oil, used worldwide as a key input in livestock and fish feeds. The Peruvian anchoveta supply chains are described, and the proposed methodology is used to model them. Three scenarios were explored: status quo of fish exploitation (Scenario 1), increase in anchoveta landings for food (Scenario 2), and radical decrease in total anchoveta landings to allow other fish stocks to prosper (Scenario 3). It was found that Scenario 2 provided the best balance of sustainability improvements among the three scenarios, but further refinement of the assessment is recommended. In the long term, the best opportunities for improving the environmental and socio-economic performance of Peruvian fisheries are related to sustainability-improving management and policy changes affecting the reduction industry. Our approach provides the tools and quantitative results to identify these best improvement opportunities. PMID:25003196

  12. Vida de leprosa: the testimony of a woman living with Hansen's disease in the Peruvian Amazon, 1947.

    PubMed

    Cueto, Marcos; de la Puente, José Carlos

    2003-01-01

    This is the narrative of a patient made before, during and after being incarcerated in an agricultural colony in the Peruvian Amazon. In a vivid style, it narrates the decay of the body, the stigma and the compulsive segregation, as well as the hope for a better life. It is the perspective of a patient, something that is difficult to find when researching the history of health. The original publication was possible thanks to the German physician Maxime H. Kuczynski-Godard and thanks to the Institute of Social Medicine of the University of San Marcos that was directed by the professor of hygiene Carlos Enrique Paz-Soldán. We have used this publication for this transcription. Kuczynski-Godard was a German medical doctor that arrived in Peru in the mid 1930s and organized valuable activities in the Peruvian jungle as a part of an effort, which eventually failed, of the Peruvian State to colonize, or really to "civilize" the Amazon.

  13. Age, maturation, and population structure of the Humboldt squid Dosidicus gigas off the Peruvian Exclusive Economic Zones

    NASA Astrophysics Data System (ADS)

    Liu, Bilin; Chen, Xinjun; Chen, Yong; Tian, Siquan; Li, Jianhua; Fang, Zhou; Yang, Mingxia

    2013-01-01

    Age, maturation and population structure of the Humboldt squid Dosidicus gigas were studied based on random sampling of the Chinese jigging fishery off the Peruvian Exclusive Economic Zones (EEZ) during 2008-2010. Estimated ages ranged from 144 to 633 days, confirming that the squid is a short-lived species with longevity no longer than 2 years. Occurrence of mature females and hatching in each month indicated that Humboldt squid spawned year-round. Back-calculated hatching dates for the samples were from January 22nd, 2008 to April 22nd, 2010 with a peak between January and March. Two size-based and two hatching date-based populations could be defined from mantle length (ML) at maturity and back-calculated hatching dates, respectively. Females matured at a larger size than males, and there was a significant difference in ML at maturity between the two hatching groups ( P <0.05). The waters adjacent to 11°S off the Peruvian EEZ may be a potential spawning ground. This study shows the complexity of the population structure and large variability in key life history parameters in the Humboldt squid off the Peruvian EEZ, which should be considered in the assessment and management of this important resource.

  14. HPV vaccine knowledge and acceptability among Peruvian men who have sex with men and transgender women: A pilot, qualitative study.

    PubMed

    Galea, Jerome T; Monsour, Emmi; Nureña, César R; Blas, Magaly M; Brown, Brandon

    2017-01-01

    Human papillomavirus (HPV) is the most common sexually transmitted infection globally and is responsible for a variety of cancers in men and women. An effective HPV vaccine licensed for use in girls and boys has been indicated for-but is not widely implemented in-men who have sex with men (MSM). Limited data are available for transgender women (TW). We explored the social and behavioral aspects related to HPV vaccine uptake and participation in HPV vaccine studies among Peruvian MSM and TW. Focus groups and individual in-depth interviews were conducted to obtain the knowledge, thoughts, and opinions from Peruvian MSM and TW regarding HPV vaccination. Data were analyzed using systematic comparative and descriptive content analysis. Three focus groups and fifteen individual in-depth interviews were conducted among 36 MSM and TW. Participant mean age was 26 years (range 18-40). Though many participants were unfamiliar with HPV vaccination, most expressed positive attitudes. Participants expressed concerns about the potential for stigma when disclosing HPV vaccination. Peruvian MSM and TW felt that HPV vaccination would be acceptable to themselves and their peers. Nonetheless, vaccine intake may be impeded by potential stigma. Findings from this study may guide HPV vaccine implementation in similar populations.

  15. [Promotion of health rights in Peru: an approach from the perspective of The Peruvian National Health Authority].

    PubMed

    Mezones-Holguín, Edward; Díaz-Romero, Ricardo; Castillo-Jayme, Jackeline; Jerí-de-Pinho, María; Benites-Zapata, Vicente; Marquez-Bobadilla, Edith; López-Dávalos, César; Philipps-Cuba, Flor de María

    2016-01-01

    In Peru, The National Health Authority (SUSALUD) is granted the responsibility to promote, protect and defend the health rights of every citizen. However, in the Peruvian Health System (PHS) there exists an insufficient culture of health rights, a low level of knowledge of health rights by the population, and a limited degree of cooperation between users, providers and funders. In light of this limited popular participation in the health rights of the citizenry, it has been necessary for SUSALUD to pursue various activities in order to promote the exercise of health rights by Peruvians. Among the strategies implemented are the development of Organized Boards of Users (OBU) and a Program of Integrated Actions for the Promotion of Health Rights (PIAPHI). The aim of both interventions is to increase the level of trust between citizens and government, which fosters and strengthens the capacity of citizens to pursue their health rights. In this article we begin with a brief presentation on the state of knowledge, attitudes and practices of users of the health system regarding their rights. Then we explain both programs, their goals and procedures, and a general description of their activities. Also, some indicators of process and some results are presented along with discussion and future prospects. We believe that the gradual implementation of the OBU and PIAPHI programs will enhance the participation of Peruvians in their health system, and will contribute positively to their empowerment and the pursuit of their health rights.

  16. Peruvian Maca: Two Scientific Names Lepidium Meyenii Walpers and Lepidium Peruvianum Chacon – Are They Phytochemically-Synonymous?

    PubMed Central

    Meissner, Henry O.; Mscisz, Alina; Kedzia, Bogdan; Pisulewski, Pawel; Piatkowska, Ewa

    2015-01-01

    Using Liquid Chromatography-Mass Spectrometry (LCMS) , profiles of the two isotypes labelled under the same common name Maca deposited in the Medicinal Plant Herbarium, in Australia and Poland, but identified under two different scientific names Lepidium meyenii Walpers (L. meyenii) and Lepidium peruvianum Chacon (L. peruvianum) are presented. The two isotypes correspond to two holotypes of Peruvian medicinal herb known under the same common name “Maca”, as originally deposited in the Herbarium of San Marcos University in Lima, Peru dated back to 1843 and 1990 respectively. The results demonstrate distinct differences in taxonomy, visual appearance, phytochemical profiles and DNA sequences of the two researched Maca isotypes, suggesting that the two Maca specimens are dissimilar and formal use of the term “synonymous” to L. meyenii and L. peruvianum may be misleading. On the basis of presented results the scientific name L. meyenii, used since 1843 up-today for cultivated Peruvian Maca by numerous reference sources worldwide, including Regulatory Bodies in the USA, EU, Australia and most lately in China, appears to be used in error and should be formally revised. It is concluded, that the isotype of cultivated Peruvian Maca labelled under its scientific name Lepidium peruvianum Chacon, provides all the characteristics peculiar to this historically-documented herb grown in Andean highlands, which may be linked to its traditional use and accepted functionality, confirmed in recent clinical study to be relevant to its present day use for expected dietary, therapeutic and health benefits.

  17. Modelling multiple threats to water security in the Peruvian Amazon using the WaterWorld Policy Support System

    NASA Astrophysics Data System (ADS)

    van Soesbergen, A. J. J.; Mulligan, M.

    2013-06-01

    This paper explores a multitude of threats to water security in the Peruvian Amazon using the WaterWorld policy support system. WaterWorld is a spatially explicit, physically-based globally-applicable model for baseline and scenario water balance that is particularly well suited to heterogeneous environments with little locally available data (e.g. ungauged basins) and which is delivered through a simple web interface, requiring little local capacity for use. The model is capable of producing a hydrological baseline representing the mean water balance for 1950-2000 and allows for examining impacts of population, climate and land use change as well as land and water management interventions on hydrology. This paper describes the application of WaterWorld to the Peruvian Amazon, an area that is increasingly under pressure from deforestation and water pollution as a result of population growth, rural to urban migration and oil and gas extraction, potentially impacting both water quantity and water quality. By applying single and combined scenarios of: climate change, deforestation around existing and planned roads, population growth and rural-urban migration, mining and oil and gas exploitation, we explore the potential combined impacts of these multiple changes on water resources in the Peruvian Amazon and discuss the likely pathways for adaptation to and mitigation against their worst effects. See Mulligan et al. (2013) for a similar analysis for the entire Amazon Basin.

  18. HIV testing among social media-using Peruvian men who have sex with men: correlates and social context.

    PubMed

    Krueger, Evan A; Chiu, ChingChe J; Menacho, Luis A; Young, Sean D

    2016-10-01

    HIV remains concentrated among men who have sex with men (MSM) in Peru, and homophobia and AIDS-related stigmas have kept the epidemic difficult to address. Gay self-identity has been associated with increased HIV testing, though this relationship has not been examined extensively. Social media use has been rapidly increasing in Peru, yet little is known about MSM social media users in Peru. This study sought to investigate the demographic, behavioral, and stigma-related factors associated with HIV testing among social media-using Peruvian MSM. Five hundred and fifty-six MSM from Lima and surrounding areas were recruited from social networking websites to complete a survey on their sexual risk behaviors. We examined the demographic and social correlates of HIV testing behavior among this sample. Younger age and non-gay identity were significantly associated with lower likelihood of getting tested in univariate analysis. After controlling for key behaviors and AIDS-related stigma, younger age remained significantly associated with decreased testing. Participants who engaged in discussions online about HIV testing were more likely to get tested, while AIDS-related stigma presented a significant barrier to testing. Stigma severity also varied significantly by sexual identity. Youth appear to be significantly less likely than older individuals to test for HIV. Among Peruvian MSM, AIDS-related stigma remains a strong predictor of willingness to get tested. Social media-based intervention work targeting Peruvian youth should encourage discussion around HIV testing, and must also address AIDS-related stigma.

  19. HPV vaccine knowledge and acceptability among Peruvian men who have sex with men and transgender women: A pilot, qualitative study

    PubMed Central

    Monsour, Emmi; Nureña, César R.; Blas, Magaly M.; Brown, Brandon

    2017-01-01

    Purpose Human papillomavirus (HPV) is the most common sexually transmitted infection globally and is responsible for a variety of cancers in men and women. An effective HPV vaccine licensed for use in girls and boys has been indicated for—but is not widely implemented in—men who have sex with men (MSM). Limited data are available for transgender women (TW). We explored the social and behavioral aspects related to HPV vaccine uptake and participation in HPV vaccine studies among Peruvian MSM and TW. Methods Focus groups and individual in-depth interviews were conducted to obtain the knowledge, thoughts, and opinions from Peruvian MSM and TW regarding HPV vaccination. Data were analyzed using systematic comparative and descriptive content analysis. Results Three focus groups and fifteen individual in-depth interviews were conducted among 36 MSM and TW. Participant mean age was 26 years (range 18–40). Though many participants were unfamiliar with HPV vaccination, most expressed positive attitudes. Participants expressed concerns about the potential for stigma when disclosing HPV vaccination. Conclusion Peruvian MSM and TW felt that HPV vaccination would be acceptable to themselves and their peers. Nonetheless, vaccine intake may be impeded by potential stigma. Findings from this study may guide HPV vaccine implementation in similar populations. PMID:28245234

  20. Polymerase chain reaction and molecular genotyping to monitor parasitological response to anti-malarial chemotherapy in the Peruvian Amazon.

    PubMed

    Ayala, Everick; Lescano, Andrés G; Gilman, Robert H; Calderón, Maritza; Pinedo, Viviana V; Terry, Hilja; Cabrera, Lilia; Vinetz, Joseph M

    2006-04-01

    Over the past decade, anti-malarial drug resistance has rapidly become a major public health problem in the Peruvian Amazon. This study compared polymerase chain reaction (PCR) to light microscopy for diagnosing and monitoring the parasitological response of malaria patients to anti-malarial chemotherapy in the Peruvian Amazon region of Iquitos. Typing of P. falciparum using MSP1, MSP2, and glutamine-rich protein distinguished among infecting parasites. Most (73%) P. falciparum patients were parasitologically resistant to sulfadoxine-pyrimethamine (RI = 10, RII = 1). Sensitivity of microscopy was lower than PCR (69% for P. vivax and 78% for P. falciparum), but parasite clearance times were comparable between microscopy and PCR. PCR sensitively and specifically detected mixed infections and low-level parasitemia indicative of drug resistance, making this approach of practical use for the control of malaria at the public health level. Genotyping malaria parasites will be useful to distinguish drug failure from new infections in clinical trials of anti-malarial drugs in the Peruvian Amazon region.

  1. Population genetic structure of traditional populations in the Peruvian Central Andes and implications for South American population history.

    PubMed

    Cabana, Graciela S; Lewis, Cecil M; Tito, Raúl Y; Covey, R Alan; Cáceres, Angela M; Cruz, Augusto F De La; Durand, Diana; Housman, Genevieve; Hulsey, Brannon I; Iannacone, Gian Carlo; López, Paul W; Martínez, Rolando; Medina, Ángel; Dávila, Olimpio Ortega; Pinto, Karla Paloma Osorio; Santillán, Susan I Polo; Domínguez, Percy Rojas; Rubel, Meagan; Smith, Heather F; Smith, Silvia E; Massa, Verónica Rubín de Celis; Lizárraga, Beatriz; Stone, Anne C

    2014-01-01

    Molecular-based characterizations of Andean peoples are traditionally conducted in the service of elucidating continent-level evolutionary processes in South America. Consequently, genetic variation among "western" Andean populations is often represented in relation to variation among "eastern" Amazon and Orinoco River Basin populations. This west-east contrast in patterns of population genetic variation is typically attributed to large-scale phenomena, such as dual founder colonization events or differing long-term microevolutionary histories. However, alternative explanations that consider the nature and causes of population genetic diversity within the Andean region remain underexplored. Here we examine population genetic diversity in the Peruvian Central Andes using data from the mtDNA first hypervariable region and Y-chromosome short tandem repeats among 17 newly sampled populations and 15 published samples. Using this geographically comprehensive data set, we first reassessed the currently accepted pattern of western versus eastern population genetic structure, which our results ultimately reject: mtDNA population diversities were lower, rather than higher, within Andean versus eastern populations, and only highland Y-chromosomes exhibited significantly higher within-population diversities compared with eastern groups. Multiple populations, including several highland samples, exhibited low genetic diversities for both genetic systems. Second, we explored whether the implementation of Inca state and Spanish colonial policies starting at about ad 1400 could have substantially restructured population genetic variation and consequently constitute a primary explanation for the extant pattern of population diversity in the Peruvian Central Andes. Our results suggest that Peruvian Central Andean population structure cannot be parsimoniously explained as the sole outcome of combined Inca and Spanish policies on the region's population demography: highland populations

  2. Cold Episodes, Their Precursors and Teleconnections in the Central Peruvian Andes (1958-2009)

    NASA Astrophysics Data System (ADS)

    Sulca, J. C.; Vuille, M. F.; Trasmonte, G.; Silva, Y.; Takahashi, K.

    2014-12-01

    The Mantaro valley (MV) is located in the central Peruvian Andes. Occasionally, cold episodes are observed during the austral summer (January-March), which strongly damage crops. However, little is known about the causes and impacts of such cold episodes in the MV. The main goal of this study is thus to characterize cold episodes in the MV and assess their large-scale circulation and teleconnections over South America (SA) during austral summer. To identify cold events in the MV daily minimum temperature for the period 1958-2009 from Huayao station, located within the MV was used. We defined a cold episode as the period when daily minimum temperature drops below the 10-percentile for at least one day. Several gridded reanalysis and satellite products were used to characterize the large-scale circulation, cloud cover and rainfall over SA associated with these events for same period. Cold episodes in the MV are associated with positive OLR anomalies, which extend over much of the central Andes, indicating reduced convective cloud cover during these extremes, but also affirm the large-scale nature of these events. At the same time, northeastern Brazil (NEB) registers negative OLR anomalies, strong convective activity and enhanced cloud cover because displacement of the South Atlantic Convergence Zone (SACZ) toward the northeast of its climatologic position. Further, it is associated with a weakening of the Bolivian High - Nordeste Low (BH-NL) system at upper levels, but also influenced by a low-level migratory high-pressure center develops at 30°S, 50°W; propagating from mid- to low latitudes as part of an extratropical Rossby wave train. In conclusion, cold episodes in the MV appear to be caused by radiative cooling associated with reduced cloudiness, rather than cold air advection. The reduced cloud cover in turn results from a robust large-scale pattern of westerly wind anomalies over central Peruvian Andes, inhibiting moisture influx, convective activity and

  3. Mercury concentrations in urine of amerindian populations near oil fields in the peruvian and ecuadorian amazon.

    PubMed

    Webb, Jena; Coomes, Oliver T; Ross, Nancy; Mergler, Donna

    2016-11-01

    Mercury is a global contaminant with toxic, persistent effects on human health. Petroleum extraction is an important source of elemental mercury; little is known about human exposure levels near oil fields in the Amazon basin. To characterize mercury levels in people living near oil production sites in the Peruvian and Ecuadorian Amazon, controlling for fish consumption, occupation, source of water and socio-demographic characteristics. Analyze mercury levels in urine samples using cold vapour atomic fluorescence spectrometry from 76 indigenous men and women in eight riverine communities situated near oil wells or pipelines. Subjects answered a questionnaire soliciting socio-demographic, occupational and dietary information. Data were analyzed using multiple linear regression modeling. The mean value of U-Hg was 2.61μg/g creatinine (95% CI: 2.14-3.08), with 7% of the sample recording values above the global background standard suggested by The World Health Organization (5μg/g creatinine). Women who used water from a surface source had two and a half times the amount of mercury in their urine (mean=3.70μg/g creatinine, 95% CI: 2.26-5.15) compared with women who used other water sources (mean =1.39μg/g creatinine, 95% CI: 0.51-2.25). Men who were involved in an oil clean-up operation had twice as much mercury in their urine (mean =3.07μg/g creatinine, 95% CI: 1.97-4.16) as did those who worked on other tasks (mean =1.56μg/g creatinine, 95% CI: 1.48-2.65). Mercury levels were not associated with the number of fish meals per week. Indigenous peoples of the Peruvian and Ecuadorian Amazon living near oil production sites generally had urine mercury levels within the global background standard suggested by the World Health Organization. Increased levels of mercury in urine were detected for men involved in oil spill remediation and for women who relied on surface water for household needs. These findings signal the need for strict safety measures to limit the amount

  4. Dynamics and fishery of the Peruvian hake: Between nature and man

    NASA Astrophysics Data System (ADS)

    Guevara-Carrasco, Renato; Lleonart, Jordi

    Mean length in the catch of Peruvian hake ( Merluccius gayi peruanus) declined drastically by 8 cm in a few months in 1992. The 1991-93 El Niño event marked the beginning of changes in bottom environmental conditions, that along with other changes in the ecosystem, were the cause of the disappearance of large sized old hake from the traditional fishing grounds and the invasion of these areas by high concentrations of small sized young hake, traditionally distributed in the southern areas. A misinterpretation of this change gave an optimistic perception of the state of the stock, leading to a large increase of the fishing fleet and therefore to an increase of the fishing pressure on this resource. Catch increased quickly to very high levels in 1996, the fishery indicators of relative abundance remained stable, while global abundance of hake was diminishing. The resource responded to these natural variations of environment and to the intense fishing pressure with changes in some aspects of its biology and ecology. The most remarkable was the decrease of the length and age at first maturity that led to spawning by 1 year old (19 cm) individuals in a species whose observed longevity was 14 years. In 2002 a total and indefinite fishery closure was established by the Peruvian government and a technical commission for the hake recovery was created, which carried out continuous monitoring of the stock. After a closure of 20 months the indicators showed signs of recovery and the fishery was reopened in 2004. However, after an encouraging beginning during 2004 and the first quarter of 2005, neither abundance nor age structure had improved by the end of 2005, and in fact were deteriorating by the start of 2006. The survival of the age 2 and 3 groups was very low and few 4+ years old individuals were observed. Several factors working at different time scales have been proposed to explain the status of hake. The impact of the fishery, variations in the abiotic environment

  5. Anti-inflammatory activity of animal oils from the Peruvian Amazon.

    PubMed

    Schmeda-Hirschmann, Guillermo; Delporte, Carla; Valenzuela-Barra, Gabriela; Silva, Ximena; Vargas-Arana, Gabriel; Lima, Beatriz; Feresin, Gabriela E

    2014-10-28

    Animal oils and fats from the fishes Electrophorus electricus and Potamotrygon motoro, the reptiles Boa constrictor, Chelonoidis denticulata (Geochelone denticulata) and Melanosuchus niger and the riverine dolphin Inia geoffrensis are used as anti-inflammatory agents in the Peruvian Amazon. The aim of the study was to assess the topic anti-inflammatory effect of the oils/fats as well as to evaluate its antimicrobial activity and fatty acid composition. The oils/fats were purchased from a traditional store at the Iquitos market of Belen, Peru. The topic anti-inflammatory effect was evaluated by the mice ear edema induced by arachidonic acid (AA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) at the dose of 3mg oil/ear. Indomethacine and nimesulide were used as reference anti-inflammatory drugs. The application resembles the traditional topical use of the oils. The antimicrobial effect of the oils/fats was assessed by the microdilution test against reference strains of Escherichia coli, Staphylococcus aureus and Salmonella enteritidis. The fatty acid composition of the oils/fats (as methyl esters) was determined by GC and GC-MS analysis after saponification. All oils/fats showed topic anti-inflammatory activity, with better effect in the TPA-induced mice ear edema assay. The most active drugs were Potamotrygon motoro, Melanosuchus niger and Geochelone denticulata. In the AA-induced assay, the best activity was found for Potamotrygon motoro and Electrophorus electricus oil. The oil of Electrophorus electricus also showed a weak antimicrobial effect with MIC values of 250 µg/mL against Escherichia coli ATCC 25922 and Salmonella enteritidis-MI. The main fatty acids in the oils were oleic, palmitic and linoleic acids. Topical application of all the oils/fats investigated showed anti-inflammatory activity in the mice ear edema assay. The effect can be related with the identity and composition of the fatty acids in the samples. This study gives support to the traditional

  6. Association of -1082 interleukin-10 gene polymorphism in Peruvian adults with chronic periodontitis

    PubMed Central

    Chambrone, Leandro; Ascarza, Amilcar; Guerrero, Maria E.; Pannuti, Claudio; de la Rosa, Manuel; Salinas-Prieto, Elmer

    2014-01-01

    Objectives: The aim of this study was to assess association of the -1082 IL-10 gene polymorphism with chronic periodontitis CP in a Peruvian population. Study Design: Samples of venous blood and DNA were obtained from 106 Peruvian subjects: a) 53 periodontally healthy; and b) 53 with CP. The association of the -1082 IL-10 promoter sequences was assessed by Polymerase chain reaction-restriction fragment length polymorfism (PCR-RFLP). Student’s t test were used to assess the clinical parameters, as well as the χ2 test and the odds ratio (OR), with 95% confidence intervals (CI) used performed for estimates regarding genotype and allele frequencies. Results: There were statistically significant differences between groups regarding the mean bleeding on probing, mean attachment level and mean probing depth (p < 0.00001) indicating that the matching based on the evaluated groups was adequate. The χ2 test found a statistically significant imbalance of genotypes between groups (p = 0.0172). The prevalence of CP was significantly higher in subjects harboring at least one A allele at position -1082 (AA and GA genotypes) in comparison to patients with the GG genotype (OR = 2.96; CI: 0.52; 5.41; p = 0.0099). Equally, subjects with the AA genotype were significantly associated to a diagnosis of CP (OR = 2.71; CI: 0.38; 5.04; p = 0.0231). On the other hand, subjects presenting a healthy periodontal status presented at least one G allele in comparison with the AA genotype (OR = 0.37; CI: 0.05, 0.69; p = 0.0231). For subjects with the GG genotype, the same positive association was observed (OR = 0.34; CI: 0.06, 0.62; p = 0.0099). There were no significant differences between groups amongst subjects with the GA genotype (OR = 1.19; CI: 0.22, 2.16; p = 0.6774). Conclusions: Within the limits of this study, IL-10 gene polymorphism at position -1082 does not appear to be associated to CP. Conversely, subjects with AA genotype seem to be at an increased risk of developing CP. Key

  7. Westward Penetration of Particulate and Dissolved Iron Redox Species from the Peruvian Margin

    NASA Astrophysics Data System (ADS)

    Heller, M. I.; Lam, P. J.; Moffett, J.

    2016-02-01

    The Peruvian margin is known for its intensive oxygen deficient zone (ODZ), which extends westward from the shelf from near surface ( 40m) to a depth of 800m. Observations of dissolved Fe (dFe) near the Peruvian margin obtained during the 2013 GEOTRACES EPZT cruise show that the westward penetration of elevated dFe concentrations is at least as great, if not greater, in the oxic waters below the ODZ compared to the ODZ. We present here particulate iron (pFe) speciation from in-situ pump samples taken concurrently during the 2013 Geotraces EPZT cruise. Most of the dFe in the ODZ was found in the Fe(II) redox state, whereas the speciation of pFe, which was examined by the use of synchrotron chemical species mapping, XANES, and EXAFS, showed that pFe was dominated by the Fe(III) redox state and was present in the form of Fe oxyhydroxides. Because the usual oxidants for dFe(II), oxygen and hydrogen peroxide, are absent in ODZs, alternative oxidants must be considered. We found that the highest concentrations of pFe and nitrite (NO2-) are co-located, suggesting that nitrogen species may play a key role in the oxidation of dFe(II) in the ODZ. In more oxygenated near-bottom waters on the slope below the ODZ, we found a much higher abundance of pFe(II). XANES spectroscopy identified these pFe(II) phases to be crystalline Fe(II) silicates such as biotite, a common mineral found in a wide variety of igneous and metamorphic rocks, likely derived from the underlying lithogenic sediment in the region. Our data suggests active redox cycling within the ODZ that partially traps shelf-derived dFe from penetrating into the interior. We postulate that elevated dFe levels in the oxic layer below the ODZ may derive from the oxic dissolution of species like those unweathered Fe(II) silicates in the slope sediments. However, it is unclear what processes convert the pFe(II) into dFe and also how dFe is stabilized so that it can be transported over a long distance.

  8. Single cell genomic study of Dehalococcoidetes species from deep-sea sediments of the Peruvian Margin

    PubMed Central

    Kaster, Anne-Kristin; Mayer-Blackwell, Koshlan; Pasarelli, Ben; Spormann, Alfred M

    2014-01-01

    The phylum Chloroflexi is one of the most frequently detected phyla in the subseafloor of the Pacific Ocean margins. Dehalogenating Chloroflexi (Dehalococcoidetes) was originally discovered as the key microorganisms mediating reductive dehalogenation via their key enzymes reductive dehalogenases (Rdh) as sole mode of energy conservation in terrestrial environments. The frequent detection of Dehalococcoidetes-related 16S rRNA and rdh genes in the marine subsurface implies a role for dissimilatory dehalorespiration in this environment; however, the two genes have never been linked to each other. To provide fundamental insights into the metabolism, genomic population structure and evolution of marine subsurface Dehalococcoidetes sp., we analyzed a non-contaminated deep-sea sediment core sample from the Peruvian Margin Ocean Drilling Program (ODP) site 1230, collected 7.3 m below the seafloor by a single cell genomic approach. We present for the first time single cell genomic data on three deep-sea Chloroflexi (Dsc) single cells from a marine subsurface environment. Two of the single cells were considered to be part of a local Dehalococcoidetes population and assembled together into a 1.38-Mb genome, which appears to be at least 85% complete. Despite a high degree of sequence-level similarity between the shared proteins in the Dsc and terrestrial Dehalococcoidetes, no evidence for catabolic reductive dehalogenation was found in Dsc. The genome content is however consistent with a strictly anaerobic organotrophic or lithotrophic lifestyle. PMID:24599070

  9. Spatio-temporal analysis of malaria incidence in the Peruvian Amazon Region between 2002 and 2013.

    PubMed

    Soto-Calle, Veronica; Rosas-Aguirre, Angel; Llanos-Cuentas, Alejandro; Abatih, Emmanuel; DeDeken, Redgi; Rodriguez, Hugo; Rosanas-Urgell, Anna; Gamboa, Dionicia; D Alessandro, Umberto; Erhart, Annette; Speybroeck, Niko

    2017-01-16

    Malaria remains a major public health problem in the Peruvian Amazon where the persistence of high-risk transmission areas (hotspots) challenges the current malaria control strategies. This study aimed at identifying significant space-time clusters of malaria incidence in Loreto region 2002-2013 and to determine significant changes across years in relation to the control measures applied. Poisson regression and purely temporal, spatial, and space-time analyses were conducted. Three significantly different periods in terms of annual incidence rates (AIR) were identified, overlapping respectively with the pre-, during, and post- implementation control activities supported by PAMAFRO project. The most likely space-time clusters of malaria incidence for P. vivax and P. falciparum corresponded to the pre- and first two years of the PAMAFRO project and were situated in the northern districts of Loreto, while secondary clusters were identified in eastern and southern districts with the latest onset and the shortest duration of PAMAFRO interventions. Malaria in Loreto was highly heterogeneous at geographical level and over time. Importantly, the excellent achievements obtained during 5 years of intensified control efforts totally vanished in only 2 to 3 years after the end of the program, calling for sustained political and financial commitment for the success of malaria elimination as ultimate goal.

  10. Needs, Acceptability, and Value of Humanitarian Medical Assistance in Remote Peruvian Amazon Riverine Communities

    PubMed Central

    Sanchez, Juan F.; Halsey, Eric S.; Bayer, Angela M.; Beltran, Martin; Razuri, Hugo R.; Velasquez, Daniel E.; Cama, Vitaliano A.; Graf, Paul C. F.; Quispe, Antonio M.; Maves, Ryan C.; Montgomery, Joel M.; Sanders, John W.; Lescano, Andres G.

    2015-01-01

    Much debate exists regarding the need, acceptability, and value of humanitarian medical assistance. We conducted a cross-sectional study on 457 children under 5 years from four remote riverine communities in the Peruvian Amazon and collected anthropometric measures, blood samples (1–4 years), and stool samples. Focus groups and key informant interviews assessed perspectives regarding medical aid delivered by foreigners. The prevalence of stunting, anemia, and intestinal parasites was 20%, 37%, and 62%, respectively. Infection with multiple parasites, usually geohelminths, was detected in 41% of children. The prevalence of intestinal parasites both individual and polyparasitism increased with age. Participants from smaller communities less exposed to foreigners expressed lack of trust and fear of them. However, participants from all communities were positive about foreigners visiting to provide health support. Prevalent health needs such as parasitic infections and anemia may be addressed by short-term medical interventions. There is a perceived openness to and acceptability of medical assistance delivered by foreign personnel. PMID:25846293

  11. Environmental enteropathy is associated with cardiometabolic risk factors in Peruvian children.

    PubMed

    Lee, G O; Olortegui, M Paredes; Salas, M Siguas; Yori, P Peñataro; Trigoso, D Rengifo; Kosek, P; Mispireta, M L; Oberhelman, R; Caulfield, L E; Kosek, M N

    2017-03-07

    Environmental enteropathy (EE) is a syndrome of altered small intestine structure and function hypothesized to be common among individuals lacking access to improved water and sanitation. There are plausible biological mechanisms, both inflammatory and non-inflammatory, by which EE may alter the cardiometabolic profile. Here, we test the hypothesis that EE is associated with the cardiometabolic profile among young children living in an environment of intense enteropathogen exposure. In total, 156 children participating in the Peruvian cohort of a multicenter study on childhood infectious diseases, growth and development were contacted at 3-5 years of age. The urinary lactulose:mannitol ratio, and plasma antibody to endotoxin core were determined in order to assess intestinal permeability and bacterial translocation. Blood pressure, anthropometry, fasting plasma glucose, insulin, and cholesterol and apolipoprotein profiles were also assessed. Extant cohort data were also used to relate biomarkers of EE during the first 18 months of life to early child cardiometabolic profile. Lower intestinal surface area, as assessed by percent mannitol excretion, was associated with lower apolipoprotein-AI and lower high-density lipoprotein concentrations. Lower intestinal surface area was also associated with greater blood pressure. Inflammation at 7 months of age was associated with higher blood pressure in later childhood. This study supports the potential for a relationship between EE and the cardiometabolic profile.

  12. Diversity of commercial sex among men and male-born trans people in three Peruvian cities

    PubMed Central

    Zúñiga, Mario; Zunt, Joseph; Mejía, Carolina; Montano, Silvia; Sánchez, Jorge L.

    2011-01-01

    In Peru, commercial sex involving men and male-born travestis, transgenders and transsexuals (CSMT) is usually represented as a dangerous practice carried out on the streets by people experiencing economic hardship and social exclusion. However, in reality little is known about the complexities of this practice in Peru. This paper presents findings from an ethnographic study of the characteristics, patterns and socio-cultural aspects of CSMT in three Peruvian cities. The study included participant observation in sex work venues and interviews with 42 sex workers and 25 key informants. We found that CSMT in Peru takes many forms (some not previously described in the country) and is practised in different places by people from various socioeconomic levels. In many cases, the practice appears linked to ideals of social mobility, migratory experiences and other economic activities. In addition, the increasing use of the internet and mobile phones has changed patterns of sex work in Peru. We review the implications of these findings for future research and public health interventions. PMID:21936651

  13. [Evaluation of the quality of information about pregnancy found in webpages according to the Peruvian guidelines].

    PubMed

    Carrillo-Larco, Rodrigo M; Pérez-Lu, José E; Alvarado-Vásquez, Eduardo; Curioso, Walter H

    2012-03-01

    The objective of this study is to evaluate the information quality about pregnancy symptoms in Spanish available in the internet. This is an analytic, cross-sectional study. In order to evaluate the selected websites, we used a methodology previously validated by Curró et al. The websites were selected from Google, MSN.com and Yahoo.com. The quality evaluation included three components: medical contents, accountability and usability of the website. The medical content was compared with the data available in the national guidelines for Comprehensive Sexual and Reproductive Health, from the Peruvian Ministry of Health. Ninety nine websites in Spanish were evaluated. From them, 26.3% had medium adherence to the gold standard document. In 37.4% the websites were of low quality. A total of 24.2% were blogs, they were associated (as a protrective factor) to sites of poor quality (OR: 0.1, 95% CI: 0.02 to 0.5). The majority of websites in Spanish related to pregnancy symptoms have low quality. These findings indicate the need to properly educate patients and general public, and a critical evaluation of the information quality found at the Internet as well.

  14. Evidence for Aedes aegypti (Diptera: Culicidae) Oviposition on Boats in the Peruvian Amazon.

    PubMed

    Guagliardo, Sarah Anne; Morrison, Amy C; Luis Barboza, Jose; Wesson, Dawn M; Ponnusamy, Loganathan; Astete, Helvio; Vazquez-Prokopec, Gonzalo; Kitron, Uriel

    2015-07-01

    Dengue vector Aedes aegypti L. is invading peri-urban and rural areas throughout Latin America. Our previous research in the Peruvian Amazon has shown that river boats are heavily infested with immature and adult Ae. aegypti mosquitoes, likely playing a major role in their long-distance dispersal and successful invasion. However, the presence of immature mosquitoes provides no information about the timing of oviposition, and whether it took place in the boats. Here, we used baited ovitraps deployed on river boats to test the hypothesis that Ae. aegypti oviposition occurs during boat travel. We deployed 360 ovitraps on 60 different barges during August and October of 2013, and February 2014 (with 20 barges sampled during each month). We found that Ae. aegypti mosquitoes in 22 individual ovitraps from 15 of the 60 barges (premise index 25%) across all sampling dates. Further, the distribution of Ae. aegypti egg abundance was highly aggregated: 2.6% of traps (N=7) were responsible for 71.8% of eggs found, and 1.5% of traps (N=4) were responsible for all (100%) of the larvae found. Similarly, 5% of boats were responsible for the 71.47% of eggs. Our results provide strong evidence that Ae. aegypti oviposition commonly occurs during boat travel. Baited ovitraps could represent a cost-effective means of monitoring and controlling mosquito populations on boats.

  15. [Environmental pollution, climate variability and climate change: a review of health impacts on the Peruvian population].

    PubMed

    Gonzales, Gustavo F; Zevallos, Alisson; Gonzales-Castañeda, Cynthia; Nuñez, Denisse; Gastañaga, Carmen; Cabezas, César; Naeher, Luke; Levy, Karen; Steenland, Kyle

    2014-01-01

    This article is a review of the pollution of water, air and the effect of climate change on the health of the Peruvian population. A major air pollutant is particulate matter less than 2.5 μ (PM 2.5). In Lima, 2,300 premature deaths annually are attributable to this pollutant. Another problem is household air pollution by using stoves burning biomass fuels, where excessive indoor exposure to PM 2.5 inside the household is responsible for approximately 3,000 annual premature deaths among adults, with another unknown number of deaths among children due to respiratory infections. Water pollution is caused by sewage discharges into rivers, minerals (arsenic) from various sources, and failure of water treatment plants. In Peru, climate change may impact the frequency and severity of El Niño Southern Oscillation (ENSO), which has been associated with an increase in cases of diseases such as cholera, malaria and dengue. Climate change increases the temperature and can extend the areas affected by vector-borne diseases, have impact on the availability of water and contamination of the air. In conclusion, Peru is going through a transition of environmental risk factors, where traditional and modern risks coexist and infectious and chronic problems remain, some of which are associated with problems of pollution of water and air.

  16. Revisiting Peruvian anchovy ( Engraulis ringens) trophodynamics provides a new vision of the Humboldt Current system

    NASA Astrophysics Data System (ADS)

    Espinoza, Pepe; Bertrand, Arnaud

    2008-10-01

    The Peruvian anchovy or anchoveta ( Engraulis ringens) forages on plankton and is a main prey for marine mammals, seabirds, fish, and fishers, and is therefore a key element of the food web in the Humboldt Current system (HCS). Here, we present results from the analysis of 21,203 anchoveta stomach contents sampled during 23 acoustic surveys over the period 1996-2003. Prey items were identified to the genus level, and the relative dietary importance of different prey was assessed by determination of their carbon content. Variability in stomach fullness was examined relative to the diel cycle, the distance from the coast, sea surface temperature, and latitude, using generalized additive models (GAMs). Whereas phytoplankton largely dominated anchoveta diets in terms of numerical abundance and comprised >99% of ingested prey items, the carbon content of prey items indicated that zooplankton was by far the most important dietary component, with euphausiids contributing 67.5% of dietary carbon followed by copepods (26.3%). Stomach fullness data showed that anchoveta feed mainly during daytime between 07h00 and 18h00, although night-time feeding also made a substantial contribution to total food consumption. Stomach fullness also varied with latitude, distance from the coast, and temperature, but with substantial variability indicating a high degree of plasticity in anchoveta feeding behaviour. The results suggest an ecological role for anchoveta that challenges current understanding of its position in the foodweb, the functioning of the HCS, and trophic models of the HCS.

  17. A Peruvian family with a novel PARK2 mutation: Clinical and pathological characteristics.

    PubMed

    Cornejo-Olivas, Mario R; Torres, Luis; Mata, Ignacio F; Mazzetti, Pilar; Rivas, Diana; Cosentino, Carlos; Inca-Martinez, Miguel; Cuba, Juan M; Zabetian, Cyrus P; Leverenz, James B

    2015-05-01

    Mutations in PARK2 result in autosomal recessive young onset Parkinson's disease (YOPD). Although there have been a number of reports on the clinical characteristics of PARK2-related PD, there is limited information available on the associated neuropathologic changes. We describe the clinical and pathological characteristics of a Peruvian family with YOPD. The proband and one unaffected sibling were screened for PARK2 dosage and point mutations. One affected sibling had detailed neuropathologic examination. Instituto Nacional de Ciencias Neurologicas (INCN) in Lima, Peru. The proband and two of her four siblings developed YOPD and both parents were unaffected. The clinical course has been characterized by akinetic-rigid parkinsonism predominantly affecting the lower limbs and dyskinesias. Analysis of PARK2 showed that the proband is compound heterozygous for a novel acceptor splice site mutation in intron 5 (IVS5-1G>A) and an exon 7 deletion. Neuropathologic assessment of an affected sibling revealed severe neuronal loss in the substantia nigra (SN) and loss of tyrosine hydroxylase immunopositive fibers in the striatum. No Lewy body pathology was observed using standard histology or immunohistochemistry for α-synuclein. Consistent with most neuropathologic reports of patients with PARK2 mutations, we did not observe Lewy body inclusions, despite marked SN degeneration and severe dopaminergic denervation of the striatum. These data describe a novel splice site mutation and further extend the clinicopathological characterization of PARK2-associated PD. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. A Peruvian family with a novel PARK2 mutation: Clinical and Pathological Characteristics

    PubMed Central

    Cornejo-Olivas, Mario; Torres, Luis; Mata, Ignacio F; Mazzetti, Pilar; Rivas, Diana; Cosentino, Carlos; Inca-Martinez, Miguel; Cuba, Juan M; Zabetian, Cyrus P.; Leverenz, James B.

    2015-01-01

    Background Mutations in PARK2 result in autosomal recessive young onset Parkinson’s disease (YOPD). Although there have been a number of reports on the clinical characteristics of PARK2-related PD, there is limited information available on the associated neuropathologic changes. Design We describe the clinical and pathological characteristics of a Peruvian family with YOPD. The proband and one unaffected sibling were screened for PARK2 dosage and point mutations. One affected sibling had detailed neuropathologic examination. Setting Instituto Nacional de Ciencias Neurologicas (INCN) in Lima, Peru Results The proband and two of her four siblings developed YOPD and both parents were unaffected. The clinical course has been characterized by akinetic-rigid parkinsonism predominantly affecting the lower limbs and dyskinesias. Analysis of PARK2 showed that the proband is compound heterozygous for a novel acceptor splice site mutation in intron 5 (IVS5-1G>A) and an exon 7 deletion. Neuropathologic assessment of an affected sibling revealed severe neuronal loss in the substantia nigra (SN) and loss of tyrosine hydroxylase immunopositive fibers in the striatum. No Lewy body pathology was observed using standard histology or immunohistochemistry for α-synuclein. Conclusions Consistent with most neuropathologic reports of patients with PARK2 mutations, we did not observe Lewy body inclusions, despite marked SN degeneration and severe dopaminergic denervation of the striatum. These data describe a novel splice site mutation and further extend the clinicopathological characterization of PARK2-associated PD. PMID:25817512

  19. Parasitic infections in juveniles of Arapaima gigas (Schinz, 1822) cultivated in the Peruvian Amazon.

    PubMed

    Delgado, Patrick Mathews; Delgado, John Paul Mathews; Orbe, Rosa Ismińo

    2013-01-01

    The paiche, Arapaima gigas represents a socio-economically important species in the Peruvian Amazon, and actually an intensive production for human consumption has emerged during the last years. Therefore, more studies are required in fish farming development, especially concerning populations of parasites that affect fish production yields. Eighty specimens of paiche collected between September and October of 2011 from semi-intensive fish farm in Loreto State, Peru, were examined for their helminthic parasites. Five species were recorded parasitizing A. gigas: Dawestrema cycloancistrium and Dawestrema cycloancistrioides (Monogenea) on gills, Trichodina sp. (Protozoa) on the skin, Caballerotrema arapaimense (Trematoda) in stomachs and Philometra senticosa (Nematoda) in the swim bladder. Highest prevalence was recorded for D. cycloancistrium (100.0%), D. cycloancistrioides (83.0%) and Trichodina sp. (50.0%) and highest values of mean intensity and mean abundance were recorded for D. cycloancistrium (260) parasites per individual. The results confirm the necessity of constant monitoring of fish, seeking the diagnosis and timely control of infestations with parasites, in order to eradicate the mortality of the host that leads unviable the fish farming intended for human consumption.

  20. Prevalence of enteroparasites and genotyping of Giardia lamblia in Peruvian children.

    PubMed

    Peréz Cordón, G; Cordova Paz Soldan, O; Vargas Vásquez, F; Velasco Soto, J R; Sempere Bordes, Ll; Sánchez Moreno, M; Rosales, M J

    2008-07-01

    Enteroparasites in children from three marginal urban districts of Trujillo (Peru) were studied to treat these children and to design a prevention and control programme. A total of 845 children were examined. The general prevalence of enteroparasites was of 66.3%, and 45.6% were multiparasitized. The pathogenic enteroparasite prevalence were 23.8% (Giardia lamblia), 4.6% (Iodamoeba buschlii), 2.6% (Cyclospora cayetanensis), 2.2% (Hymenolepis nana), and 2% (Cryptosporidium spp.). G. lamblia was the most frequent parasite both in diarrheic children (28.1%) as well as in nondiarrheic ones (19.5%). The G. lamblia genotypes were molecularly characterized by sequence analysis of the glutamate dehydrogenase (gdh) gene using PCR and RFLP. Sequence analysis revealed both Assemblage A (AI and AII) and Assemblage B (BIV), with the predominance of Assemblage AI. All the samples with Assemblage A were diarrheic but not those with Assemblage B. This is the first study of molecular characterization of G. lamblia in Peruvian children and confirms the importance of asymptomatic patients in the transmission of the giardiosis, especially in places with poor hygiene and sanitation.

  1. Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands.

    PubMed

    Gonzales, Gustavo F

    2012-01-01

    Lepidium meyenii (maca) is a Peruvian plant of the Brassicaceae family cultivated for more than 2000 years, which grows exclusively in the central Andes between 4000 and 4500 m altitude. Maca is used as a food supplement and also for its medicinal properties described traditionally. Since the 90s of the XX century, an increasing interest in products from maca has been observed in many parts of the world. In the last decade, exportation of maca from Peru has increased from 1,415,000 USD in 2001 to USD 6,170,000 USD in 2010. Experimental scientific evidence showed that maca has nutritional, energizer, and fertility-enhancer properties, and it acts on sexual dysfunctions, osteoporosis, benign prostatic hyperplasia, memory and learning, and protects skin against ultraviolet radiation. Clinical trials showed efficacy of maca on sexual dysfunctions as well as increasing sperm count and motility. Maca is a plant with great potential as an adaptogen and appears to be promising as a nutraceutical in the prevention of several diseases.

  2. Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010

    PubMed Central

    Oré, Marianela; Sáenz, Eliana; Cabrera, Rufino; Sanchez, Juan F.; De Los Santos, Maxy B.; Lucas, Carmen M.; Núñez, Jorge H.; Edgel, Kimberly A.; Sopan, Justino; Fernández, Jorge; Carnero, Andres M.; Baldeviano, G. Christian; Arrasco, Juan C.; Graf, Paul C. F.; Lescano, Andres G.

    2015-01-01

    Military personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2–36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL. Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (∼ 70%; P < 0.001). After emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries. PMID:26078320

  3. Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010.

    PubMed

    Oré, Marianela; Sáenz, Eliana; Cabrera, Rufino; Sanchez, Juan F; De Los Santos, Maxy B; Lucas, Carmen M; Núñez, Jorge H; Edgel, Kimberly A; Sopan, Justino; Fernández, Jorge; Carnero, Andres M; Baldeviano, G Christian; Arrasco, Juan C; Graf, Paul C F; Lescano, Andres G

    2015-08-01

    Military personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2-36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL. Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (~70%; P < 0.001). After emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries.

  4. pic gene of enteroaggregative Escherichia coli and its association with diarrhea in Peruvian children.

    PubMed

    Durand, David; Contreras, Carmen A; Mosquito, Susan; Ruíz, Joaquim; Cleary, Thomas G; Ochoa, Theresa J

    2016-08-01

    Enteroaggregative Escherichia coli (EAEC) causes acute and persistent diarrhea among children, HIV-infected patients, and travelers to developing countries. We have searched for 18 genes-encoding virulence factors associated with aggregative adherence, dispersion, biofilm, toxins, serine protease autotransporters of Enterobacteriaceae (SPATEs) and siderophores, analyzed in 172 well-characterized EAEC strains (aggR(+)) isolated from stool samples of 97 children with diarrhea and 75 healthy controls from a passive surveillance diarrhea cohort study in Peru. Eighty-one different genetic profiles were identified, 37 were found only associated with diarrhea and 25 with control samples. The most frequent genetic profile was aggC(+)aatA(+)aap(+)shf(+)fyuA(+), present in 19 strains, including diarrhea and controls. The profile set1A(+)set1B(+)pic(+) was associated with diarrhea (P < 0.05). Of all genes evaluated, the most frequent were aatA (CVD 342) present in 159 strains (92.4%) and fyuA in 157 (91.3%). When EAEC strains were analyzed as a single pathogen (excluding co-infections), only pic was associated with diarrhea (P < 0.05) and with prolonged diarrhea (diarrhea ≥ 7 days) (P < 0.05). In summary, this is the first report on the prevalence of a large set of EAEC virulence genes and its association with diarrhea in Peruvian children. More studies are needed to elucidate the exact role of each virulence factor.

  5. Outbreak of Group A beta hemolytic Streptococcus pharyngitis in a Peruvian military facility, April 2012.

    PubMed

    Ramos, Mariana; Valle, Ruben; Reaves, Eric J; Loayza, Luis; Gonzalez, Sofia; Bernal, Maria; Soto, Giselle; Hawksworth, Anthony W; Kasper, Matthew R; Tilley, Drake H; De Mattos, Carlos A; Brown, Jason R; Bausch, David G

    2013-06-01

    Group A Streptococcus (GAS), or Streptococcus pyogenes, is a common cause of acute pharyngitis as well as other diseases. Closed populations such as those living on military bases, nursing homes, and prisons are particularly vulnerable to GAS outbreaks due to crowding that facilitates person-to-person transmission. This report details a large outbreak of GAS pharyngitis at a Peruvian military training facility near Lima, Peru, in April 2012. Initial findings showed 145 cases. However, as the investigation continued it was revealed that some trainees may have concealed their illness to avoid real or perceived negative consequences of seeking medical care. A subsequent anonymous survey of all trainees revealed at least 383 cases of pharyngitis among the facility's 1,549 trainees and an attack rate of 34 percent among the 1,137 respondents. The epidemic curve revealed a pattern consistent with routine person-to-person transmission, although a point-source initiating event could not be excluded. Laboratory results showed GAS emm type 80.1 to be the culprit pathogen, an organism not commonly implicated in outbreaks of GAS in the Americas. Barious unique and illustrative features of outbreak investigation in military facilities and populations are discussed.

  6. Evidence for Holocene stability of steep slopes, northern Peruvian Andes, based on soils and radiocarbon dates

    USGS Publications Warehouse

    Miller, D.C.; Birkeland, P.W.; Rodbell, D.T.

    1993-01-01

    Radiocarbon dating and soil relationships indicate that landscapes in highaltitude glaciated valleys of the northern Peruvian Andes have been remarkably stable during the Holocene. Radiocarbon dates show that deglaciation was underway by 12 ka, and that slopes and alluvial fans at the bases of slopes were essentially stabilized by at least 8 ka. The soils consist of fine-grained loessial A horizons overlying Bw horizons in gravelly till or alluvial-fan gravel. Following deglaciation, widespread gullying took place in till on the steep (maximum angle: 37??) sideslopes of most valleys; the eroded material was deposited as fans at the bases of the slopes. Loess was then deposited as a fairly uniform blanket across most elements of the landscape. Soil formation began during or following loess deposition, and because soil-profile morphology is sufficiently similar at most sites, soil formation has been a dominant process during much of the Holocene. This remarkable stability, especially for such steep slopes, is attributed to a combination of tight packing of the till, permeability of the capping loess, rapid revegetation following ice retreat, and roots from the present grassland vegetation and possibly former forests. ?? 1993.

  7. Pregnancy outcomes associated with Cesarean deliveries in Peruvian public health facilities

    PubMed Central

    Gonzales, Gustavo F; Tapia, Vilma L; Fort, Alfredo L; Betran, Ana Pilar

    2013-01-01

    A continuous rise in the rate of cesarean deliveries has been reported in many countries over recent decades. This trend has prompted the emergence of a debate on the risks and benefits associated with cesarean section. The present study was designed to estimate cesarean section rates over time during the period between 2000 and 2010 in Peru and to present outcomes for each mode of delivery. This is a secondary analysis of a large database obtained from the Perinatal Information System, which includes 570,997 pregnant women and their babies from 43 Peruvian public health facilities in three geographical regions: coast, highlands, and jungle. Over 10 years, 558,901 women delivered 563,668 infants weighing at least 500 g. The cesarean section rate increased from 25.5% in 2000 to 29.9% in 2010 (26.9% average; P < 0.01). The rate of stillbirths was lower with cesarean than vaginal deliveries (P < 0.01). On the other hand, and as expected, the rates for preterm births, twin pregnancies, and preeclampsia were higher in women who delivered by cesarean section (P < 0.01). More importantly, the rate of maternal mortality was 5.5 times higher in the cesarean section group than in the vaginal delivery group. Data suggest that cesarean sections are associated with adverse pregnancy outcomes. PMID:24124393

  8. Single cell genomic study of Dehalococcoidetes species from deep-sea sediments of the Peruvian Margin.

    PubMed

    Kaster, Anne-Kristin; Mayer-Blackwell, Koshlan; Pasarelli, Ben; Spormann, Alfred M

    2014-09-01

    The phylum Chloroflexi is one of the most frequently detected phyla in the subseafloor of the Pacific Ocean margins. Dehalogenating Chloroflexi (Dehalococcoidetes) was originally discovered as the key microorganisms mediating reductive dehalogenation via their key enzymes reductive dehalogenases (Rdh) as sole mode of energy conservation in terrestrial environments. The frequent detection of Dehalococcoidetes-related 16S rRNA and rdh genes in the marine subsurface implies a role for dissimilatory dehalorespiration in this environment; however, the two genes have never been linked to each other. To provide fundamental insights into the metabolism, genomic population structure and evolution of marine subsurface Dehalococcoidetes sp., we analyzed a non-contaminated deep-sea sediment core sample from the Peruvian Margin Ocean Drilling Program (ODP) site 1230, collected 7.3 m below the seafloor by a single cell genomic approach. We present for the first time single cell genomic data on three deep-sea Chloroflexi (Dsc) single cells from a marine subsurface environment. Two of the single cells were considered to be part of a local Dehalococcoidetes population and assembled together into a 1.38-Mb genome, which appears to be at least 85% complete. Despite a high degree of sequence-level similarity between the shared proteins in the Dsc and terrestrial Dehalococcoidetes, no evidence for catabolic reductive dehalogenation was found in Dsc. The genome content is however consistent with a strictly anaerobic organotrophic or lithotrophic lifestyle.

  9. Tuberculosis and nutrition: disease perceptions and health seeking behavior of household contacts in the Peruvian Amazon

    PubMed Central

    Baldwin, M. R.; Yori, P. P.; Ford, C.; Moore, D. A. J.; Gilman, R. H.; Vidal, C.; Ticona, E.; Evans, C. A.

    2010-01-01

    SETTING Households of TB patients in the Peruvian Amazon. OBJECTIVE To investigate how knowledge and beliefs of household contacts about TB affected health seeking behavior. DESIGN Interviews with 73 patients finishing treatment and 79 of their adult household contacts. RESULTS Contacts were knowledgeable about free screening and treatment, but contacts who noted weight loss, not cough, were more likely to be screened for TB (P = 0.03). Forty-two per cent reported that TB was prevented by nutrition, 28% by separating eating utensils, and only 19% by avoiding a coughing patient. Only one household contact reported being stigmatized. Stigma centered upon nutrition, and only 12% knew of the association between TB and HIV. Only 14% had a BMI <20, yet 30% reported regularly going to sleep hungry. Free food packages were reported to be the most important reason for treatment adherence by 33% of patients. CONCLUSION Contacts misperceived TB as a nutritional disease and did not fear airborne transmission, which should be corrected by public health education. Weight loss, and not cough, led to screening. Stigma appeared to be minimized because risk was perceived as personal, through malnutrition, rather than exposure-based. Nutritional incentives that utilize these beliefs may reduce diagnostic delay and enhance treatment adherence. PMID:15636496

  10. Persistent Strongyloidiasis Complicated by Recurrent Meningitis in an HTLV Seropositive Peruvian Migrant Resettled in Italy

    PubMed Central

    Zammarchi, Lorenzo; Montagnani, Francesca; Tordini, Giacinta; Gotuzzo, Eduardo; Bisoffi, Zeno; Bartoloni, Alessandro; De Luca, Andrea

    2015-01-01

    We describe a case of persistent strongyloidiasis complicated by recurrent meningitis, in a human T cell lymphotropic virus type 1 (HTLV-1) seropositive Peruvian migrant adult resettled in Italy. He was admitted with signs and symptoms of acute bacterial meningitis, reporting four other meningitis episodes in the past 6 years, with an etiological diagnosis of Escherichia coli and Enterococcus faecium in two cases. He had been previously treated with several antihelmintic regimens not including ivermectin, without eradication of strongyloidiasis, and he had never been tested for HTLV before. During the described episode, the patient was treated for meningitis with broad-spectrum antibiotic therapy and 200 μg/kg/dose oral ivermectin once daily on day 1, 2, 15 and 16 with full recovery and no further episodes of meningitis. The presented case underlines several critical points concerning the management of poorly known neglected diseases such as strongyloidiasis and HTLV infection in low-endemic areas. Despite several admissions for meningitis and strongyloidiasis, the parasitic infection was not adequately treated and the patient was not previously tested for HTLV. The supply of ivermectin and the choice of treatment scheme was challenging since ivermectin is not approved in Italy and there are no standardized guidelines for the treatment of severe strongyloidiasis in HTLV seropositive subjects. PMID:25846292

  11. Geographic distribution and demography of Pithecia aequatorialis (pitheciidae) in Peruvian Amazonia.

    PubMed

    Aquino, Rolando; Cornejo, Fanny M; Pezo Lozano, Etersit; Heymann, Eckhard W

    2009-12-01

    To study the geographic distribution and demographic characteristics of Pithecia aequatorialis in Peruvian Amazonia, we undertook surveys and transect census in three river basins (Río Itaya, Río Tigre and Río Curaray) between 2004 and 2008. A total of 123 groups of P. aequatorialis was encountered during 1623 km of transect walks. Group size was uniform among the three areas (3.4-3.6 individuals), but surprisingly, population densities were higher in the area with strong hunting pressure (Río Itaya: 7.8 ind./km(2), vs. 5.6 and 5.9 km(2) in the Río Tigre and Río Curaray basins, respectively). The most common group composition included an adult pair with one offspring. Groups with more than one adult male and/or female accounted for 35% of sightings. Our observations extend P. aequatorialis range in Peru further south to the area between the Río Tigre and Río Corrientes, but exclude the area to the north between the Río Curaray and Río Napo. These findings are in contrast to previous distribution maps. P. aequatorialis was rarely seen in interspecific association during our censuses.

  12. [The "Chaco": eatable medicinal clay in the Peruvian highlands and his properties in digestive diseases].

    PubMed

    Castillo Contreras, Ofelia; Frisancho Velarde, Oscar

    2015-01-01

    The inhabitants of the peruvian-bolivian plateau consume a natural substance known as "Chaco", widespread since pre-Columbian era and appreciated for its digestive properties. The Chaco is an edible medicinal clay that is used as slurry with water to restrain dyspeptic discomfort or acid-peptic manifestations. In this contribution we present physicochemical aspects of the composition of the Chaco, experimental animal studies that evaluate its antiulcer effect and in vitro test that studies the antacid property. The proposed mechanism of therapeutic action is due to a cytoprotective effect on the gastric mucosa by independent mechanisms of acid secretion inhibition, as it has no antacid property in vitro. Also it has an adsorptivity to different organic molecules due to their large surface area and tetrahedral charge that makes it to interact with polar substances such as water and toxins. The other purpose of this special contribution is to recognize the coexistence of "Traditional Medicine" and "Western Medicine", a situation which leads to the need for preclinical research of various natural resources.

  13. Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands

    PubMed Central

    Gonzales, Gustavo F.

    2012-01-01

    Lepidium meyenii (maca) is a Peruvian plant of the Brassicaceae family cultivated for more than 2000 years, which grows exclusively in the central Andes between 4000 and 4500 m altitude. Maca is used as a food supplement and also for its medicinal properties described traditionally. Since the 90s of the XX century, an increasing interest in products from maca has been observed in many parts of the world. In the last decade, exportation of maca from Peru has increased from 1,415,000 USD in 2001 to USD 6,170,000 USD in 2010. Experimental scientific evidence showed that maca has nutritional, energizer, and fertility-enhancer properties, and it acts on sexual dysfunctions, osteoporosis, benign prostatic hyperplasia, memory and learning, and protects skin against ultraviolet radiation. Clinical trials showed efficacy of maca on sexual dysfunctions as well as increasing sperm count and motility. Maca is a plant with great potential as an adaptogen and appears to be promising as a nutraceutical in the prevention of several diseases. PMID:21977053

  14. Asháninka Palm Management and Domestication in the Peruvian Amazon.

    PubMed

    Sosnowska, Joanna; Walanus, Adam; Balslev, Henrik

    Palms are a natural resource that has been abundantly used by Amerindians for centuries. Only a few palm domestications have been reported in the American tropics, where there is great diversity of the Arecaceae family. We report the results of a survey combining ethnobotanical and ecological methods to study the past and present management and distribution of palms by the Asháninka indigenous people from the Tambo river region in the Peruvian Amazon. Our objectives were to document palm-related traditional ecological knowledge, to examine correlation between palm abundance and Asháninka management practices and social exchange of palm resources, and to address the question of how the Asháninka have modified palm diversity and distribution in their territory. We found that most palm species have multiple uses; the most intensively managed were palms that provide thatch, notably Attalea phalerata, Oenocarpus mapora and Phytelephas macrocarpa. Of these, Attalea phalerata was the most commonly cultivated and was found only in cultivated stands. Our results have implications for understanding the domestication of Attalea weberbaueri, which is a landrace within the Attalea phalerata complex. A closer understanding of this process would require morphometric and genetic methods to compare wild and managed populations.

  15. Late Pleistocene equilibrium-line reconstructions in the northern Peruvian Andes

    USGS Publications Warehouse

    Rodbell, D.T.

    1992-01-01

    ELA reconstructions using the toe-to-headwall-altitude ratio method for paleoglaciers in the Cordilleras Blanca and Oriental, northern Peruvian Andes indicate that ELAs during the last glacial maximum (LGM; marine isotope stage 2)) were c.4300 m in the Cordillera Blanca, c.3900-3600 m on the west side of the Cordillera Oriental, and c.3200 m on the east (Amazon Basin) side of the Cordillera Oriental. Comparison with estimated modern ELAs and glaciation thresholds indicate that ELA depression ranged from c.700 m in the Cordillera Blanca to c.1200 m on the east side of the Cordillera Oriental. Palynological evidence for drier conditions during the LGM in the tropical Andes suggests that ELA depression of this amount involved a temperature reduction (>5-6??C) that greatly exceeded the tropical sea-surface temperature depression estimates of CLIMAP (<2??C). The west to east increase in ELA depression during the LGM indicates that the steep modern precipitation gradients may have been even steeper during the LGM. -from Author

  16. The drugs industry and peasant self-defence in a Peruvian cocaine enclave.

    PubMed

    van Dun, Mirella

    2012-11-01

    This article gives a detailed account of the cocaine industry and the related violence in the Peruvian Upper Huallaga. It is argued that in this cocaine producing region violence increased during state-led forced eradication operations of the coca plants. Most of the violent incidents were closely related to the diminishing cocaine industry, but they were also related to the actions of the state security forces. Instead of receiving support from the state's security apparatus, the population mobilized its own forces to fight the violence. As will be argued, the causes of violence in this cocaine enclave are part of a dynamic interaction amongst many factors - an interaction that is influenced by the local context, a partial state vacuum, and the social utility and the economic advantages of violence. One needs to be aware that motivations of those who engage in the violent behaviour can change over time, as underlying power structures are influenced by changes in local conditions. The study covers an in-depth account of events taking place in the Upper Huallaga during the years 2003-2007. The research material was collected by several ethnographical fieldwork methods.

  17. Modeling River Hydrologic Regime and Spawning of Migratory Catfishes in Southeastern Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Canas, C. M.; Waylen, P. R.

    2008-05-01

    Seasonal hydrologic conditions and catfish larvae production were evaluated in the Madre de Dios River in order to determine whether environmental conditions influence the reproductive activity of a group of large, commercially important catfishes, in the Southeastern Peruvian Amazon. A simple stochastic model of floods is presented to describe the influence of the natural high flow regime on observed patterns of catfish larvae release and drifting. Daily river stage records at Puerto Maldonado are related to weekly larval catches to determine the association between flood and spawning events. On the basis of hydroclimatologic characteristics of Andean- Amazon regions, available long-term historical rainfall records are employed to approximate the likely inter- annual variability of floods within this Amazon headwater basin. Major larval drift appeared associated with stages of over the 5 m, or "Biologic Hydrologic Significant Events" (BSE), which act as triggers, or a reasonable surrogates, for spawning responses of these species. The timing of BSEs, estimated from the historical rainfall records, appear to be uniformly distributed during the rain season and their inter-arrival times exponential. These observations provided the basis of the stochastic model describing the likelihood of volumes of larvae releases from the headwater region to lowland Amazon. The ecologically significant role of the hydroclimatology of this region in the complete life cycle of this important Amazon fish resource is illustrated.

  18. Oil pollution in soils and sediments from the Northern Peruvian Amazon.

    PubMed

    Rosell-Melé, Antoni; Moraleda-Cibrián, Núria; Cartró-Sabaté, Mar; Colomer-Ventura, Ferran; Mayor, Pedro; Orta-Martínez, Martí

    2018-01-01

    Oil has been extracted from the Northern Peruvian Amazon for over four decades. However, few scientific studies have assessed the impacts of such activities in the environment and health of indigenous communities in the region. We have investigated the occurrence of petrogenic hydrocarbon pollution in soils and sediments from areas favoured as hunting or fishing grounds by local indigenous inhabitants. The study was conducted in one of the most productive oil blocks in Peru, located in the headwaters of the Amazon river. Soils and river sediments, in the vicinity of oil extraction and processing infrastructure, contained an oil pollution signature as attested by the occurrence of hopanes and steranes. Given the lack of any other significant source of oil pollution in the region, the sources of hydrocarbons are likely to be the activities of the oil industry in the oil block, from voluntary discharges or accidental spills. Spillage of produced water was commonplace until 2009. Moreover, petrogenic compounds were absent in control samples in sites far removed from any oil infrastructure in the oil block. Our findings suggest that wildlife and indigenous populations in this region of the Amazon are exposed to the ingestion of oil polluted soils and sediments. The data obtained supports previous claims that the local spillage of oil and produced waters in the water courses in the Corrientes and Pastaza basins could have eventually reached the main water course of the Amazon. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Spatio-temporal analysis of malaria incidence in the Peruvian Amazon Region between 2002 and 2013

    PubMed Central

    Soto-Calle, Veronica; Rosas-Aguirre, Angel; Llanos-Cuentas, Alejandro; Abatih, Emmanuel; DeDeken, Redgi; Rodriguez, Hugo; Rosanas-Urgell, Anna; Gamboa, Dionicia; D´Alessandro, Umberto; Erhart, Annette; Speybroeck, Niko

    2017-01-01

    Malaria remains a major public health problem in the Peruvian Amazon where the persistence of high-risk transmission areas (hotspots) challenges the current malaria control strategies. This study aimed at identifying significant space-time clusters of malaria incidence in Loreto region 2002–2013 and to determine significant changes across years in relation to the control measures applied. Poisson regression and purely temporal, spatial, and space-time analyses were conducted. Three significantly different periods in terms of annual incidence rates (AIR) were identified, overlapping respectively with the pre-, during, and post- implementation control activities supported by PAMAFRO project. The most likely space-time clusters of malaria incidence for P. vivax and P. falciparum corresponded to the pre- and first two years of the PAMAFRO project and were situated in the northern districts of Loreto, while secondary clusters were identified in eastern and southern districts with the latest onset and the shortest duration of PAMAFRO interventions. Malaria in Loreto was highly heterogeneous at geographical level and over time. Importantly, the excellent achievements obtained during 5 years of intensified control efforts totally vanished in only 2 to 3 years after the end of the program, calling for sustained political and financial commitment for the success of malaria elimination as ultimate goal. PMID:28091560

  20. Glanzmann thrombasthenia in a 17-year-old Peruvian Paso mare.

    PubMed

    Sanz, Macarena G; Wills, Tamara B; Christopherson, Peter; Hines, Melissa T

    2011-03-01

    A 17-year-old Peruvian Paso mare was evaluated for bilateral epistaxis that had been present for at least 3 years. The mare had mild anemia, platelet count within the reference interval, unremarkable coagulation times, and a negative Coggins test. On endoscopic examination, structural abnormalities were not observed in the nasal cavities, pharynx, larynx, trachea, or either guttural pouch, but petechiation was noted in the nasal mucosa. Additional tests revealed prolonged cutaneous bleeding time, normal concentration of von Willebrand factor antigen, an abnormal clot retraction test, and failure of plalelet aggregation in response to agonists, suggesting a functional disorder of platelets. Genetic analysis indicated the horse was homozygous for a 10-base-pair deletion that included the last 3 base pairs of exon 11 and the first 7 base pairs of intron 11 of the gene encoding glycoprotein IIb. The diagnosis was Glanzmann thrombasthenia (GT) caused by a structural defect in glycoprotein IIb. GT is an autosomal recessive disorder caused by a defect in the glycoprotein IIb-IIIa complex on platelet surfaces. Separate genes encode each glycoprotein, and mutations in either gene can result in GT. This case of GT is unique given the age of the mare at the time of diagnosis. We conclude that GT, although an inherited disorder, should be considered in horses with suspected dysfunctional platelets, regardless of age. ©2011 American Society for Veterinary Clinical Pathology.

  1. [Colorectal cancer in young adults: clinical and epidemiological features in the Peruvian population].

    PubMed

    Luna-Abanto, Jorge; Rafael-Horna, Eliana; Gil-Olivares, Fradis

    2017-01-01

    To determine the clinical epidemiological characteristics of young adult patients with colorectal cancer. Information collected by the Direccion General de Epidemiologia by the surveillance strategy in non-communicable diseases for the period 2006-2014 was requested. The rate of age-adjusted incidence and a descriptive statistical analysis of the variables studied were calculated. 1261 CRC cases were reported in patients between 20-49 years of age. The annual percentage change (APC) for the incidence is declining -0.09% (p=0.004). The CPA for CRC cases was -3.9% in men (p=0.009) and -5.22% in women (p=0.014). 640 women and 621 men were reported. Most cases of CRC in the studied population is the group of 40-49 years with 60.3% of cases. Lima was the region with the highest number of reported cases (42.6%). 63.7% of CRC cases were represented by colon tumors. Based on case reports provided by the DGE, there is a trend of decrease in the incidence of CRC cases in young adults Peruvian in the last 10 years.

  2. [Ioduria and iodine concentration in table salt in Peruvian elementary schoolchildren].

    PubMed

    Tarqui-Mamani, Carolina; Alvarez-Dongo, Doris; Fernández-Tinco, Inés

    2016-01-01

    To determine the ioduria and iodine concentration in table salt in Peruvian elementary schoolchildren. A cross-sectional study was performed. A total of 8,023 elementary schoolchildren, who voluntarily participated, were included. Multistage stratified probability sampling was performed, and the sample was obtained by systematic selection. Ioduria was determined via spectrophotometry (Sandell-Kolthoff method), and the amount of iodine in salt was evaluated volumetrically. The data were processed by means of analysis for complex samples with a weighting factor. Medians, percentiles, and confidence intervals were calculated, and the Mann-Whitney U and Kruskal-Wallis H tests were used, where appropriate. Nationwide, the median ioduria in schoolchildren was 258.53 ug/L, being higher in boys (265.90 ug/L) than in girls (250.77 ug/L). The median ioduria in urban areas was higher (289.89 ug/L) than that in rural areas (199.67 ug/L), while it was 315.48 ug/L in private schools and 241.56 ug/L in public schools (p<0.001). The median iodine concentration in table salt was 28.69 mg/kg. Of the total salt samples, 23.1% contained less than 15 mg/kg of iodine. The median ioduria in elementary schoolchildren exceeded normal levels, according to the criteria of the World Health Organization, with differences between urban and rural areas and public and private schools.

  3. Association between Allergic Rhinitis and Asthma Control in Peruvian School Children: A Cross-Sectional Study

    PubMed Central

    Uceda, Mónica; Ziegler, Otto; Lindo, Felipe; Herrera-Pérez, Eder

    2013-01-01

    Background. Asthma and allergic rhinitis are highly prevalent conditions that cause major illness worldwide. This study aimed to assess the association between allergic rhinitis and asthma control in Peruvian school children. Methods. A cross-sectional study was conducted among 256 children with asthma recruited in 5 schools from Lima and Callao cities. The outcome was asthma control assessed by the asthma control test. A score test for trend of odds was used to evaluate the association between allergic rhinitis severity and the prevalence of inadequate asthma control. A generalized linear regression model was used to estimate the adjusted prevalence ratios of inadequate asthma control. Results. Allergic rhinitis was present in 66.4% of the population with asthma. The trend analysis showed a positive association between allergic rhinitis and the probability of inadequate asthma control (P < 0.001). It was associated with an increased prevalence of inadequate asthma control, with adjusted prevalence ratios of 1.53 (95% confidence interval: 1.19−1.98). Conclusion. This study indicates that allergic rhinitis is associated with an inadequate level of asthma control, giving support to the recommendation of evaluating rhinitis to improve asthma control in children. PMID:23984414

  4. Birth month associations with height, head circumference, and limb lengths among Peruvian children.

    PubMed

    Pomeroy, Emma; Wells, Jonathan C K; Stanojevic, Sanja; Miranda, J Jaime; Cole, Tim J; Stock, Jay T

    2014-05-01

    Associations between season of birth and body size, morbidity, and mortality have been widely documented, but it is unclear whether different parts of the body are differentially sensitive, and if such effects persist through childhood. This may be relevant to understanding the relationship between early life environment and body size and proportions. We investigated associations between birth month and anthropometry among rural highland (n = 162) and urban lowland (n = 184) Peruvian children aged 6 months to 8 years. Stature; head-trunk height; total limb, ulna, tibia, hand, and foot lengths; head circumference; and limb measurements relative to head-trunk height were converted to internal age-sex-specific z scores. Lowland and highland datasets were then analyzed separately for birth month trends using cosinor analysis, as urban conditions likely provide a more consistent environment compared with anticipated seasonal variation in the rural highlands. Among highland children birth month associations were significant most strongly for tibia length, followed by total lower limb length and stature, with a peak among November births. Results were not significant for other measurements or among lowland children. The results suggest a prenatal or early postnatal environmental effect on growth that is more marked in limb lengths than trunk length or head size, and persists across the age range studied. We suggest that the results may reflect seasonal variation in maternal nutrition in the rural highlands, but other hypotheses such as variation in maternal vitamin D levels cannot be excluded.

  5. Incidence of respiratory viruses in Peruvian children with acute respiratory infections.

    PubMed

    del Valle Mendoza, Juana; Cornejo-Tapia, Angela; Weilg, Pablo; Verne, Eduardo; Nazario-Fuertes, Ronald; Ugarte, Claudia; del Valle, Luis J; Pumarola, Tomás

    2015-06-01

    Acute respiratory infections are responsible for high morbi-mortality in Peruvian children. However, the etiological agents are poorly identified. This study, conducted during the pandemic outbreak of H1N1 influenza in 2009, aims to determine the main etiological agents responsible for acute respiratory infections in children from Lima, Peru. Nasopharyngeal swabs collected from 717 children with acute respiratory infections between January 2009 and December 2010 were analyzed by multiplex RT-PCR for 13 respiratory viruses: influenza A, B, and C virus; parainfluenza virus (PIV) 1, 2, 3, and 4; and human respiratory syncytial virus (RSV) A and B, among others. Samples were also tested with direct fluorescent-antibodies (DFA) for six respiratory viruses. RT-PCR and DFA detected respiratory viruses in 240 (33.5%) and 85 (11.9%) cases, respectively. The most common etiological agents were RSV-A (15.3%), followed by influenza A (4.6%), PIV-1 (3.6%), and PIV-2 (1.8%). The viruses identified by DFA corresponded to RSV (5.9%) and influenza A (1.8%). Therefore, respiratory syncytial viruses (RSV) were found to be the most common etiology of acute respiratory infections. The authors suggest that active surveillance be conducted to identify the causative agents and improve clinical management, especially in the context of possible circulation of pandemic viruses.

  6. Brief Sensation Seeking Scale: Latent structure of 8-item and 4-item versions in Peruvian adolescents.

    PubMed

    Merino-Soto, Cesar; Salas Blas, Edwin

    2017-07-14

    This research intended to validate two brief scales of sensations seeking with Peruvian adolescents: the eight item scale (BSSS8; Hoyle, Stephenson, Palmgreen, Lorch, y Donohew, 2002) and the four item scale (BSSS4; Stephenson, Hoyle, Slater, y Palmgreen, 2003). Questionnaires were administered to 618 voluntary participants, with an average age of 13.6 years, from different levels of high school, state and private school in a district in the south of Lima. It analyzed the internal structure of both short versions using three models: a) unidimensional (M1), b) oblique or related dimensions (M2), and c) the bifactor model (M3). Results show that both instruments have a single dimension which best represents the variability of the items; a fact that can be explained both by the complexity of the concept and by the small number of items representing each factor, which is more noticeable in the BSSS4. Reliability is within levels found by previous studies: alpha: .745 = BSSS8 and BSSS4 =. 643; omega coefficient: .747 in BSSS8 and .651 in BSSS4. These are considered suitable for the type of instruments studied. Based on the correlation between the two instruments, it was found that there are satisfactory levels of equivalence between the BSSS8 and BSSS4. However, it is recommended that the BSSS4 is mainly used for research and for the purpose of describing populations.

  7. Investigation of the antioxidant and aldose reductase inhibitory activities of extracts from Peruvian tea plant infusions.

    PubMed

    Wang, Zhiqiang; Hwang, Seung Hwan; Guillen Quispe, Yanymee N; Gonzales Arce, Paul H; Lim, Soon Sung

    2017-09-15

    In the present study, the antioxidant and aldose reductase inhibitory activities of 24 Peruvian infusion tea plants were investigated by 2,2'-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and aldose reductase assays. Phoradendron sp. showed the highest inhibition of aldose reductase (IC50, 1.09±0.06μg/mL) and considerable antioxidant (IC50 of DPPH, 58.36±1.65μg/mL; IC50 of ABTS, 9.91±0.43μg/mL) effects. In order to identify the antioxidants and aldose reductase inhibitors of Phoradendron sp., DPPH-high performance liquid chromatography (HPLC) and ultrafiltration-HPLC assays were performed. Chlorogenic acid, 3,5-di-O-caffeoylquinic acid, and 1,3,5-tri-O-caffeoylquinic acid were identified as the antioxidants and aldose reductase inhibitors; apigenin was identified as the antioxidant. Finally, Phoradendron sp. and its aldose reductase inhibitors also showed a dose-dependent anti-inflammatory effect without cellular toxicity. These results suggested that Phoradendron sp. can be a potent functional food ingredient as an antioxidant, aldose reductase inhibitor and anti-inflammatory agent. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Time and mode of exhumation of the Cordillera Blanca batholith (Peruvian Andes)

    NASA Astrophysics Data System (ADS)

    Margirier, Audrey; Audin, Laurence; Robert, Xavier; Herman, Frédéric; Ganne, Jérôme; Schwartz, Stéphane

    2016-08-01

    The Cordillera Blanca batholith (12-5 Myr) forms the highest Peruvian summits and builds the footwall of the Cordillera Blanca normal fault (CBNF). Even if several models have been proposed, the processes driving both the exhumation of the Cordillera Blanca and extensional deformation along the CBNF are still debated. Here we quantify the emplacement depth and exhumation of the batholith of the northern Peru arc from the late Miocene to present. Based on a compilation of crystallization ages and new thermobarometry data in the Cordillera Blanca batholith, we propose that the batholith was emplaced at a depth of ~3 km in successive sills from 14 to 5 Ma. By contrast, the younger rocks exposed at the surface were emplaced the deepest (i.e., ~6 km) and are located close to the CBNF, suggesting post 5 Ma tilting. Furthermore, a formal inversion of the thermochronologic data indicates an increase of the exhumation rates in the Cordillera Blanca during the Quaternary. The higher predicted exhumation rates correlate with areas of high relief, both in the northern and central part of the Cordillera Blanca, suggesting that Quaternary valley carving by glaciations have a significant impact on the latest stage of the Cordillera Blanca exhumation (2-0 Ma).

  9. [Prevalence of bacterial vaginosis and associated factors in twenty peruvian cities].

    PubMed

    López-Torres, Lorena; Chiappe, Marina; Cárcamo, César; Garnett, Geoff; Holmes, King; García, Patricia

    2016-01-01

    To determine the prevalence of bacterial vaginosis (BV) and associated factors among 18-29-year-old women in 20 Peruvian cities using PREVEN project data. In this cross-sectional study, BV was defined using previously provided vaginal discharge samples on slides, which were Gram stained and observed under a microscope to determine the Nugent scores. A BV diagnosis was applied to samples with scores of 7-10. Prevalence ratios (PR) and 95% confidence intervals (95% CI) were estimated using generalized linear models. A total of 6,322 women participated in the epidemiological survey and provided vaginal swabs. The prevalence of BV was 23.7% (95% CI: 22.6-24.7) and was associated with a greater number of sexual partners in the last 12 months (PR: 1.22, 95% CI: 1.03-1.44, p=0.020 for two partners; PR: 1.46, 95% CI: 1.23-1.74, p<0.001 for three or more partners), not using a condom during last intercourse (PR: 1.16, 95% CI: 1.01-1.34, p=0.034), being a sierra resident (PR: 1.18, 95% CI: 1.05-1.31, p=0.004), and having abnormal vaginal discharge or a bad smell (PR: 1.20, 95% CI: 1.09-1.33, p<0.001). The high prevalence of BV highlights the need to strengthen health services aimed at the detection and treatment of this condition.

  10. We need to "ikarar the kutipados": intercultural understanding and health care in the Peruvian Amazon.

    PubMed

    Yajahuanca, Rosário Avellaneda; Diniz, Carmen Simone Grilo; Cabral, Cristiane da Silva

    2015-09-01

    The scope of this qualitative research was to describe and analyze how the Kukamas Kukamirias indigenous population from the Peruvian Amazon perceives and evaluates the healthcare offered by health workers at the local San Regis health post. An ethnographic-based study was conducted among the San Regis community on the Marañon River in the Loreto district of Peru, including interviews and participative observations with female and male patients as well as with traditional healers and professional health workers. An intercultural perspective is adopted to discuss the evaluations made by the Kukamas Kukamirias about the healthcare offered by professionals at their local health post. Issues examined include the intercultural matches and mismatches that affect vulnerable groups of the population in their interactions with the health services. The frequent preference shown for traditional treatment implies a close relationship between the healer and the person who is sick. This means that conventional forms of healthcare should be seen from an intercultural perspective and taken into account when organizing and articulating health services.

  11. Conservation performance of different conservation governance regimes in the Peruvian Amazon.

    PubMed

    Schleicher, Judith; Peres, Carlos A; Amano, Tatsuya; Llactayo, William; Leader-Williams, Nigel

    2017-09-12

    State-controlled protected areas (PAs) have dominated conservation strategies globally, yet their performance relative to other governance regimes is rarely assessed comprehensively. Furthermore, performance indicators of forest PAs are typically restricted to deforestation, although the extent of forest degradation is greater. We address these shortfalls through an empirical impact evaluation of state PAs, Indigenous Territories (ITs), and civil society and private Conservation Concessions (CCs) on deforestation and degradation throughout the Peruvian Amazon. We integrated remote-sensing data with environmental and socio-economic datasets, and used propensity-score matching to assess: (i) how deforestation and degradation varied across governance regimes between 2006-2011; (ii) their proximate drivers; and (iii) whether state PAs, CCs and ITs avoided deforestation and degradation compared with logging and mining concessions, and the unprotected landscape. CCs, state PAs, and ITs all avoided deforestation and degradation compared to analogous areas in the unprotected landscape. CCs and ITs were on average more effective in this respect than state PAs, showing that local governance can be equally or more effective than centralized state regimes. However, there were no consistent differences between conservation governance regimes when matched to logging and mining concessions. Future impact assessments would therefore benefit from further disentangling governance regimes across unprotected land.

  12. Radiocarbon dating of the Peruvian Chachapoya/Inca site at the Laguna de los Condores

    NASA Astrophysics Data System (ADS)

    Wild, Eva Maria; Guillen, Sonia; Kutschera, Walter; Seidler, Horst; Steier, Peter

    2007-06-01

    In 1997 a new archaeological site was discovered in the Peruvian tropical rain forest. The site is located in an area which has been occupied by the Chachapoya, a pre-Incan people, from about 800AD on. The site comprises a large funerary place with several mausoleums built in the cliffs next to the Laguna de los Condores. More than 200 human mummies and funerary bone-bundles together with numerous grave artefacts have been found there. Although the site has been ascribed to the Chachapoya, the mummification method used is very similar to the one applied by the Inca. As part of an ongoing multidisciplinary project to explore the history of this site and of the Chachapoya people, twenty-seven (27) 14C-AMS age determinations were performed. Samples, bones and textile wrappings as well as samples from a funerary bone bundle plus associated grave artefacts were dated. The 14C data show that the site originates from the Chachapoya pre-Inca period and that in addition, it was used as a funerary place during the subsequent Inca occupation era. The radiocarbon results indicate that the Chachapoya may have changed their burial tradition due to the colonization by the Inca.

  13. Asset accumulation and transfer for old age: a study on Peruvian and Moroccan migration to Spain.

    PubMed

    Escrivá, Angeles

    2013-12-01

    Population ageing constitutes a major determinant of contemporary international migration, acting both as a push and pull factor in countries of origin and reception. From a micro-perspective, longevity, economic instability and migration are also affecting personal life as well as family organisation and solidarity. The aim of this paper is to focus on the strategies, in individual and family spheres, that migrants and their loved ones develop to accumulate and transfer assets, in order to respond to the demands of the elderly and counteract the uncertainties of advancing age. To capture this reality we conducted in-depth interviews and focus groups with Peruvian and Moroccan migrants in Spain, and with returnees and relatives in the two countries of origin between 2006 and 2010. Both cases demonstrate that country contexts, together with personal experiences and family relationships, determine where to stay, and with whom or with what to support oneself as one grows older. More recently, the economic crisis in Spain that is negatively influencing social and migration policies, reducing migrants' economic gains, and placing new burdens on people's shoulders, is affecting these asset accumulation and transfer activities for old age.

  14. Taenia solium infection in a rural community in the Peruvian Andes.

    PubMed

    Moro, P L; Lopera, L; Bonifacio, N; Gilman, R H; Silva, B; Verastegui, M; Gonzales, A; Garcia, H H; Cabrera, L

    2003-06-01

    An epidemiological study was conducted in a highland, rural community in Peru, to determine the seroprevalences of human and porcine infection with Taenia solium and the risk factors associated with human infection. The seroprevalences, determined using an assay based on enzyme-linked-immuno-electrotransfer blots (EITB), were 21% (66/316) in the humans and 65% (32/49) in the pigs. The human subjects aged <30 years were more likely to be positive for anti-T. solium antibodies than the older subjects (P < 0.001). The risk factors associated with human seropositivity were lack of education beyond the elementary level [odds ratio (OR)=2.69; 95% confidence interval (CI)=1.09-6.65] and pig-raising (OR=1.68; CI=0.96-2.92). Curiously, sheep-raising was inversely associated with human T. solium infection (OR=0.50; CI=0.28-0.90). The study site appears to be a new endemic focus for T. solium in the central Peruvian Andes. Although, in earlier studies, the seroprevalence of T. solium infection has generally been found to increase with age, the opposite trend was observed in the present study. The results of follow-up studies should help determine if the relatively high seroprevalence in the young subjects of the present study is the result of a transient antibody response.

  15. A new species of Phrynopus (Anura: Craugastoridae) from the central Peruvian Andes.

    PubMed

    Mamani, Luis; Malqui, Sergio

    2014-07-17

    We describe a new species of Phrynopus from the humid grassland of Distrito de Comas, Provincia Concepcion, Department of Junin. The new species is diagnosed by the lack of dentigerous processes of vomers, tympanic annulus and membrane imperceptible through the skin, males with nuptial pads and vocal slits, warty dorsal skin, and aerolate throat, belly and ventral surfaces of thighs, by possessing pronounced subconical tubercles in the post-tympanic area, by having rounded finger and toe tips with no disc structure, and by its overall dark brown to black coloration with few white and yellow spots in the dorsum and a dark-brown belly with white to gray blotches. Specimens were found under stones at a single area of the central Peruvian Andes at elevations between 4205-4490 m.a.s.l. The eggs had an average diameter of 4.3 mm. With the description and naming of the new species, the genus Phrynopus now contains 26 species, all of them endemic to Peru, and five of which are restricted to Departamento Junin.

  16. Diversity of commercial sex among men and male-born trans people in three Peruvian cities.

    PubMed

    Nureña, César R; Zúñiga, Mario; Zunt, Joseph; Mejía, Carolina; Montano, Silvia; Sánchez, Jorge L

    2011-11-01

    In Peru, commercial sex involving men and male-born travestis, transgenders and transsexuals (CSMT) is usually represented as a dangerous practice carried out on the streets by people experiencing economic hardship and social exclusion. However, in reality little is known about the complexities of this practice in Peru. This paper presents findings from an ethnographic study of the characteristics, patterns and sociocultural aspects of CSMT in three Peruvian cities. The study included participant observation in sex work venues and interviews with 42 sex workers and 25 key informants. We found that CSMT in Peru takes many forms (some not previously described in the country) and is practised in different places by people from various socioeconomic levels. In many cases, the practice appears linked to ideals of social mobility, migratory experiences and other economic activities. In addition, the increasing use of the Internet and mobile phones has changed patterns of sex work in Peru. We review the implications of these findings for future research and public health interventions.

  17. Accelerated losses of protected forests from gold mining in the Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Asner, Gregory P.; Tupayachi, Raul

    2016-09-01

    Gold mining in Amazonia involves forest removal, soil excavation, and the use of liquid mercury, which together pose a major threat to biodiversity, water quality, forest carbon stocks, and human health. Within the global biodiversity hotspot of Madre de Dios, Peru, gold mining has continued despite numerous 2012 government decrees and enforcement actions against it. Mining is now also thought to have entered federally protected areas, but the rates of miner encroachment are unknown. Here, we utilize high-resolution remote sensing to assess annual changes in gold mining extent from 1999 to 2016 throughout the Madre de Dios region, including the high-diversity Tambopata National Reserve and buffer zone. Regionally, gold mining-related losses of forest averaged 4437 ha yr-1. A temporary downward inflection in the annual growth rate of mining-related forest loss following 2012 government action was followed by a near doubling of the deforestation rate from mining in 2013-2014. The total estimated area of gold mining throughout the region increased about 40% between 2012 and 2016, including in the Tambopata National Reserve. Our results reveal an urgent need for more socio-environmental effort and law enforcement action to combat illegal gold mining in the Peruvian Amazon.

  18. Developmental and physical-fitness associations with gross motor coordination problems in Peruvian children.

    PubMed

    de Chaves, Raquel Nichele; Bustamante Valdívia, Alcibíades; Nevill, Alan; Freitas, Duarte; Tani, Go; Katzmarzyk, Peter T; Maia, José António Ribeiro

    2016-01-01

    The aims of this cross-sectional study were to examine the developmental characteristics (biological maturation and body size) associated with gross motor coordination problems in 5193 Peruvian children (2787 girls) aged 6-14 years from different geographical locations, and to investigate how the probability that children suffer with gross motor coordination problems varies with physical fitness. Children with gross motor coordination problems were more likely to have lower flexibility and explosive strength levels, having adjusted for age, sex, maturation and study site. Older children were more likely to suffer from gross motor coordination problems, as were those with greater body mass index. However, more mature children were less likely to have gross motor coordination problems, although children who live at sea level or at high altitude were more likely to suffer from gross motor coordination problems than children living in the jungle. Our results provide evidence that children and adolescents with lower physical fitness are more likely to have gross motor coordination difficulties. The identification of youths with gross motor coordination problems and providing them with effective intervention programs is an important priority in order to overcome such developmental problems, and help to improve their general health status. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. The influence of human settlements on the parasite community in two species of Peruvian tamarin.

    PubMed

    Wenz, A; Heymann, E W; Petney, T N; Taraschewski, H F

    2010-04-01

    Although there is a growing recognition that the transfer of diseases between humans and non-human primates can be of great significance for conservation biology, there have been only a few studies focusing on parasites. In this study, saddleback (Saguinus fuscicollis) and moustached tamarin (Saguinus mystax) from the rainforest of the Peruvian lowlands were used as models to determine helminth parasite associations between canopy-dwelling primate species and a nearby human settlement. The human population showed high prevalences of infestation with a number of nematodes, including Ascaris lumbricoides (88.9%), Trichuris trichiura (37%) and hookworms (55.6%). However, the ova of these geohelminths were not detectable in tamarin faeces. Thus, no direct parasite transfer from humans to non-human primates could be documented. However, tamarin groups with more frequent contact to humans and their facilities had significantly higher prevalences and egg output of Prosthenorchis elegans, an important primate pathogen, than a forest group. In contrast, a cestode was significantly more common with more egg output in sylvatic than in human-associated groups. Human alteration of the habitat is likely to play a major role in determining the occurrence, prevalence and intensity of helminth infestation of wild non-human primates.

  20. General biochemical and immunological characteristics of the venom from Peruvian scorpion Hadruroides lunatus.

    PubMed

    Costal-Oliveira, F; Duarte, C G; Machado de Avila, R A; Melo, M M; Bordon, K C F; Arantes, E C; Paredes, N C; Tintaya, B; Bonilla, C; Bonilla, R E; Suarez, W S; Yarleque, A; Fernandez, J M; Kalapothakis, E; Chávez-Olórtegui, Carlos

    2012-10-01

    This communication describes the general biochemical properties and some immunological characteristics of the venom from the Peruvian scorpion Hadruroides lunatus, which is the most medically relevant species in Peru. The soluble venom of this scorpion is toxic to mice, the LD₅₀ determined was 0.1 mg/kg and 21.55 mg/kg when the venom was injected intracranial or intraperitoneally, respectively. The soluble venom displayed proteolytic, hyaluronidasic, phospholipasic and cardiotoxic activities. High performance liquid chromatography of the soluble venom resulted in the separation of 20 fractions. Two peptides with phospholipasic activity were isolated to homogeneity and their molecular masses determined by mass spectrometry (MALDI TOF). Anti-H. lunatus venom sera were produced in rabbits. Western blotting analysis showed that most of the protein content of this venom is immunogenic. H. lunatus anti-venom displayed consistent cross-reactivity with venom antigens from the new World-scorpions Tityus serrulatus and Centruroides sculpturatus venoms; however, a weaker reactivity was observed against the venom antigens from the old World-scorpion Androctonus australis Hector.

  1. [Adapting a private health care facility to the new Peruvian Public Health Sistem. Quality rating in a Middle Income Economy country].

    PubMed

    Andrissi, Laura

    2015-01-01

    The aim of the study is the Assessment of Quality Sevices provided by a no-profit Medical Center in Peruvian Sierra, through an evidence-based decision-making process to identify infrastructure and capacity building interventions, to achieve accreditation and economic sustainability and increase competitiveness in the renewed Peruvian National Health System. The quali-quantitative collection of data shows how is fundamental an Healthcare Management focused on the responsiveness of services to the real needs and the local culture to reach the goals.

  2. Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations

    PubMed Central

    O. Meissner, Henry; Mscisz, Alina; Piatkowska, Ewa; Baraniak, Marek; Mielcarek, Sebastian; Kedzia, Bogdan; Holderna-Kedzia, Elzbieta; Pisulewski, Pawel

    2016-01-01

    Peruvian Maca crops (Lepidium peruvianum), grown in two geographically-distant cultivation sites located at similar altitudes in the highlands of the Peruvian Andes (Junin at 4,200 m a.s.l. and Ancash 4,150 m a.s.l.), were used in the study. Four prime Maca phenotypes, distinguished by hypocotyl colours labelled as “Yellow”, “Purple”, “Red” and “Black” were selected to determine distribution in levels and corresponding ratios between individual Glucosinolates (Glucotropaeolin and m-methylglucotropaeolin) in an attempt to identify four Peruvian Maca phenotypes from analyses of powdered hypocotyls. There were highly significant differences (P<0.01) in hypocotyl weight/size of four Maca phenotypes harvested in two locations. The Junin crop represented a mostly “large” class (13.3 g) with “small” size hypocotyls (7.2 g), while a “small” class was predominant in Ancash (3.5 g). Powdered Yellow Maca showed significantly higher (P<0.001) microbial contamination than the other three, with Black Maca being the least infected. Only minor, statistically-confirmed differences were detected in nutritive characteristics between the four Maca phenotypes grown in Junin, however highly significant differences (P<0.01) in Glucosinolates existed between the Red and Black Maca grown in Junin and Ancash. Irrespective of the cultivation location, Red phenotypes showed the highest content of Total Glucosinolates, followed by Black and Purple, with the Yellow phenotype showing consistently lower levels. Highly significant P<0.01) differences determined in ratios of individual Glucosinolates between four Maca phenotypes grown in two locations, confirms an earlier assumption that sums of individual Glucosinolates, their ratios and profiles, may be feasible to explore in analytically identifying individual Maca phenotypes in pulverised marketed Maca products. PMID:27127450

  3. Multilocus genotyping reveals high heterogeneity and strong local population structure of the Plasmodium vivax population in the Peruvian Amazon

    PubMed Central

    2010-01-01

    Background Peru is one of the Latin American countries with the highest malaria burden, mainly due to Plasmodium vivax infections. However, little is known about P. vivax transmission dynamics in the Peruvian Amazon, where most malaria cases occur. The genetic diversity and population structure of P. vivax isolates collected in different communities around Iquitos city, the capital of the Peruvian Amazon, was determined. Methods Plasmodium vivax population structure was determined by multilocus genotyping with 16 microsatellites on 159 P. vivax infected blood samples (mono-infections) collected in four sites around Iquitos city. The population characteristics were assessed only in samples with monoclonal infections (n = 94), and the genetic diversity was determined by calculating the expected heterozygosity and allelic richness. Both linkage disequilibrium and the genetic differentiation (θ) were estimated. Results The proportion of polyclonal infections varied substantially by site (11% - 70%), with the expected heterozygosity ranging between 0.44 and 0.69; no haplotypes were shared between the different populations. Linkage disequilibrium was present in all populations (IAS 0.14 - 0.61) but was higher in those with fewer polyclonal infections, suggesting inbreeding and a clonal population structure. Strong population differentiation (θ = 0.45) was found and the Bayesian inference cluster analysis identified six clusters based on distinctive allele frequencies. Conclusion The P. vivax populations circulating in the Peruvian Amazon basin are genetically diverse, strongly differentiated and they have a low effective recombination rate. These results are in line with the low and clustered pattern of malaria transmission observed in the region around Iquitos city. PMID:20525233

  4. [Use of standardized blood smear slide sets for competency assessment in the malaria microscopic diagnosis in the Peruvian Amazon].

    PubMed

    Rosas-Aguirre, Ángel; Gamboa, Dionicia; Rodriguez, Hugo; Llanos-Zavalaga, Fernando; Aguirre, Kristhian; Llanos-Cuentas, Alejandro

    2010-01-01

    To assess the competency of microscopists for malaria diagnosis using standardized slide sets in the Peruvian Amazon. Cross-sectional study carried out in 122 first level health facilities of the Peruvian Amazon, between July and September 2007. Within the frame of the project "Control Malaria in the border areas of the Andean Region: A community approach" (PAMAFRO), we evaluated the malaria diagnosis performance in 68 microscopists without expertise (< 1 year of expertise) and 76 microscopists with expertise (> 1 year) using standardized sets of 20 blood smear slides according to the World Health Organization (WHO) recommendations. A correct diagnosis (correct species identification) was defined as "agreement", a microscopist was qualified as an "expert" if they have an agreement ≥90% (≥ 18 slides with correct diagnosis), as a "referent" with an agreement between 80% and <90%, "competent" if they are between 70 and <80% and "in training" if they have <70%. Microscopists with expertise (68.6%) had more agreement than those without expertise (48.2%). The competency assessment was acceptable (competent, referent, or experts levels) in 11.8% of the microscopists without expertise and in 52.6% from those with expertise. The agreement was lower using blood smear slides with P. falciparum with low parasitaemia, with P. malariae and with mixed infections. Is the first assessment, we found only one of three microscopists from the Peruvian Amazon is competent fro malaria diagnosis according to the WHO standards. From this baseline data, we have to continue working in order to improve the competency assessment of the microscopists within the frame of a quality assurance system.

  5. Morphological and genetic diversity of camu-camu [Myrciaria dubia (Kunth) McVaugh] in the Peruvian Amazon

    PubMed Central

    Šmíd, Jan; Kalousová, Marie; Mandák, Bohumil; Houška, Jakub; Chládová, Anna; Pinedo, Mario

    2017-01-01

    Camu-camu [Myrciaria dubia (Kunth) McVaugh] is currently an important and promising fruit species grown in the Peruvian Amazon, as well as in Brazil, Colombia, and Bolivia. The species is valued for its high content of fruit-based vitamin C. Large plantations have been established only in the last two decades, and a substantial part of the production is still obtained by collecting fruits from the wild. Domestication of the species is at an early stage; most farmers cultivate the plants without any breeding, or only through a simple mass selection process. The main objective of the study was to characterize morphological and genetic variation within and among cultivated and natural populations of camu-camu in the Peruvian Amazon. In total, we sampled 13 populations: ten wild in the Iquitos region, and three cultivated in the Pucallpa region in the Peruvian Amazon. To assess the genetic diversity using seven microsatellite loci, we analyzed samples from ten individual trees per each population (n = 126). Morphological data was collected from five trees from each population (n = 65). The analysis did not reveal statistically significant differences for most of the morphological descriptors. For wild and cultivated populations, the observed heterozygosity was 0.347 and 0.404 (expected 0.516 and 0.506), and the fixation index was 0.328 and 0.200, respectively. Wild populations could be divided into two groups according to the UPGMA and STRUCTURE analysis. In cultivated populations, their approximate origin was determined. Our findings indicate a high genetic diversity among the populations, but also a high degree of inbreeding within the populations. This can be explained by either the isolation of these populations from each other or the low number of individuals in some populations. This high level of genetic diversity can be explored for the selection of superior individuals for further breeding. PMID:28658316

  6. Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations.

    PubMed

    O Meissner, Henry; Mscisz, Alina; Piatkowska, Ewa; Baraniak, Marek; Mielcarek, Sebastian; Kedzia, Bogdan; Holderna-Kedzia, Elzbieta; Pisulewski, Pawel

    2016-03-01

    Peruvian Maca crops (Lepidium peruvianum), grown in two geographically-distant cultivation sites located at similar altitudes in the highlands of the Peruvian Andes (Junin at 4,200 m a.s.l. and Ancash 4,150 m a.s.l.), were used in the study. Four prime Maca phenotypes, distinguished by hypocotyl colours labelled as "Yellow", "Purple", "Red" and "Black" were selected to determine distribution in levels and corresponding ratios between individual Glucosinolates (Glucotropaeolin and m-methylglucotropaeolin) in an attempt to identify four Peruvian Maca phenotypes from analyses of powdered hypocotyls. There were highly significant differences (P<0.01) in hypocotyl weight/size of four Maca phenotypes harvested in two locations. The Junin crop represented a mostly "large" class (13.3 g) with "small" size hypocotyls (7.2 g), while a "small" class was predominant in Ancash (3.5 g). Powdered Yellow Maca showed significantly higher (P<0.001) microbial contamination than the other three, with Black Maca being the least infected. Only minor, statistically-confirmed differences were detected in nutritive characteristics between the four Maca phenotypes grown in Junin, however highly significant differences (P<0.01) in Glucosinolates existed between the Red and Black Maca grown in Junin and Ancash. Irrespective of the cultivation location, Red phenotypes showed the highest content of Total Glucosinolates, followed by Black and Purple, with the Yellow phenotype showing consistently lower levels. Highly significant P<0.01) differences determined in ratios of individual Glucosinolates between four Maca phenotypes grown in two locations, confirms an earlier assumption that sums of individual Glucosinolates, their ratios and profiles, may be feasible to explore in analytically identifying individual Maca phenotypes in pulverised marketed Maca products.

  7. Reconstructing past upwelling intensity and the seasonal dynamics of primary productivity along the Peruvian coastline from mollusk shell stable isotopes

    NASA Astrophysics Data System (ADS)

    Sadler, James; Carré, Matthieu; Azzoug, Moufok; Schauer, Andrew J.; Ledesma, Jesus; Cardenas, Fredy; Chase, Brian M.; Bentaleb, Ilhem; Muller, Serge D.; Mandeng, Magloire; Rohling, Eelco J.; Sachs, Julian P.

    2012-01-01

    We present here a potential new method to evaluate past variations of the mean intensity of Peruvian coastal upwelling and of the seasonal timing of phytoplankton blooms. This method uses a combination of the monthly carbon and oxygen isotopic signals preserved in fossil mollusk shells, and a series of corrections to extract the variations of the dissolved inorganic carbon (DIC) δ13C. Based on the analysis of five shell samples (85 shells in total) from the southern Peruvian coast, we suggest that the mean coastal upwelling intensity can be determined from a linear relationship between average values of corrected shell δ13C and δ18O. This new potential proxy would bring additional independent information valuable to interpret paleoproductivity changes reconstructed from marine sediment of the nearby continental shelf. Results obtained on fossil samples from the middle Holocene show an increase in upwelling intensity during this period associated to a spatial reorganization of upwelling centers along the South Peruvian coast. At the seasonal scale, corrected shell δ13C enrichment indicates a phytoplankton bloom. Seasonal timing of phytoplankton blooms can be estimated by the lag with the annual temperature cycle reproduced by shell δ18O monthly variations. The results obtained with two modern shell samples indicate phytoplankton blooms occurring during summer and fall, consistently with in situ productivity observations. Our method relies on revisited assumptions about the influence of temperature and metabolism in mollusk shell δ13C. We further discussed the validity of these assumptions and the potential implications for the interpretation of similar data sets.

  8. Direction and timing of uplift propagation in the Peruvian Andes deduced from molecular phylogenetics of highland biotaxa

    NASA Astrophysics Data System (ADS)

    Picard, Damien; Sempere, Thierry; Plantard, Olivier

    2008-07-01

    Physical paleoaltimetric methods are increasingly used to estimate the amount and timing of surface uplift in orogens. Because the rise of mountains creates new ecosystems and triggers evolutionary changes, biological data may also be used to assess the development and timing of regional surface uplift. Here we apply this idea to the Peruvian Andes through a molecular phylogeographic and phylochronologic analysis of Globodera pallida, a potato parasite nematode that requires cool temperatures and thus thrives above 2.0-2.5 km in these tropical highlands. The Peruvian populations of this species exhibit a clear evolutionary pattern with deeper, more ancient lineages occurring in Andean southern Peru and shallower, younger lineages occurring progressively northwards. Genetically diverging G. pallida populations thus progressively colonized highland areas as these were expanding northwards, demonstrating that altitude in the Peruvian Andes was acquired longitudinally from south to north, i.e. in the direction of decreasing orogenic volume. This phylogeographic structure is recognized in other, independent highland biotaxa, and point to the Central Andean Orocline (CAO) as the region where high altitudes first emerged. Moreover, molecular clocks relative to Andean taxa, including the potato-tomato group, consistently estimate that altitudes high enough to induce biotic radiation were first acquired in the Early Miocene. After calibration by geological and biological tie-points and intervals, the phylogeny of G. pallida is used as a molecular clock, which estimates that the 2.0-2.5 km threshold elevation range was reached in the Early Miocene in southernmost Peru, in the Middle and Late Miocene in the Abancay segment (NW southern Peru), and from the latest Miocene in central and northern Peru. Although uncertainties attached to phylochronologic ages are significantly larger than those derived from geochronological methods, these results are fairly consistent with coeval

  9. Characteristics and publication patterns of theses from a Peruvian medical school.

    PubMed

    Arriola-Quiroz, Isaias; Curioso, Walter H; Cruz-Encarnacion, Maria; Gayoso, Oscar

    2010-06-01

    Many medical schools require a student thesis before graduation. Publishing results in a peer-reviewed journal could be an indicator of scientific value and acceptability by the scientific community. The publication pattern of theses published by medical students in Peru is unknown. The aim of this study was to assess the characteristics and publication pattern of theses in biomedical-indexed journals conducted by medical students in a university with the highest research output in Peru. Data from registered theses between 2000 and 2003 were obtained from the university library. Publication of theses in biomedical journals was assessed in 2008 by a search strategy using PubMed, Google Scholar, LILACS, LIPECS and SciELO. Four hundred and eighty-two medical theses were registered between 2000 and 2003; 85 (17.6%) were published in biomedical-indexed journals. Of the published theses, 28 (5.8%) were published in MEDLINE-indexed journals, 55 (11.4%) in SciELO-indexed journals, 61 (12.6%) in LILACS-indexed journals and 68 (14.1%) in LIPECS-indexed journals. Most of the published theses (80%) were in Spanish and published in Peruvian journals; and 17 theses (20%) were published in foreign journals (all of them indexed in MEDLINE). In addition, 37 (43.5%) belong primarily to internal medicine, and 24 (28.2%) belong primarily to infectious diseases. Medical students were first authors in 71 (83.5%) of the articles. In this study, most of the published theses were in Spanish, published in local journals and indexed in LIPECS. The percentage of published theses in biomedical journals at this university is comparable with others coming from developed countries.

  10. Multiple Norovirus Infections in a Birth Cohort in a Peruvian Periurban Community

    PubMed Central

    Saito, Mayuko; Goel-Apaza, Sonia; Espetia, Susan; Velasquez, Daniel; Cabrera, Lilia; Loli, Sebastian; Crabtree, Jean E.; Black, Robert E.; Kosek, Margaret; Checkley, William; Zimic, Mirko; Bern, Caryn; Cama, Vitaliano; Gilman, Robert H.; Xiao, L.; Kelleher, D.; Windle, H. J.; van Doorn, L. J.; Varela, M.; Verastegui, M.; Calderon, M.; Alva, A.; Roman, K.

    2014-01-01

    Background. Human noroviruses are among the most common enteropathogens globally, and are a leading cause of infant diarrhea in developing countries. However, data measuring the impact of norovirus at the community level are sparse. Methods. We followed a birth cohort of children to estimate norovirus infection and diarrhea incidence in a Peruvian community. Stool samples from diarrheal episodes and randomly selected nondiarrheal samples were tested by polymerase chain reaction for norovirus genogroup and genotype. Excretion duration and rotavirus coinfection were evaluated in a subset of episodes. Results. Two hundred twenty and 189 children were followed to 1 and 2 years of age, respectively. By 1 year, 80% (95% confidence interval [CI], 75%–85%) experienced at least 1 norovirus infection and by 2 years, 71% (95% CI, 65%–77%) had at least 1 episode of norovirus-associated diarrhea. Genogroup II (GII) infections were 3 times more frequent than genogroup 1 (GI) infections. Eighteen genotypes were found; GII genotype 4 accounted for 41%. Median excretion duration was 34.5 days for GII vs 8.5 days for GI infection (P = .0006). Repeat infections by the same genogroup were common, but repeat infections by the same genotype were rare. Mean length-for-age z score at 12 months was lower among children with prior norovirus infection compared to uninfected children (coefficient: −0.33 [95% CI, −.65 to −.01]; P = .04); the effect persisted at 24 months. Conclusions. Norovirus infection occurs early in life and children experience serial infections with multiple genotypes, suggesting genotype-specific immunity. An effective vaccine would have a substantial impact on morbidity, but may need to target multiple genotypes. PMID:24300042

  11. Beyond birth-weight: early growth and adolescent blood pressure in a Peruvian population.

    PubMed

    Sterling, Robie; Checkley, William; Gilman, Robert H; Cabrera, Lilia; Sterling, Charles R; Bern, Caryn; Miranda, J Jaime

    2014-01-01

    Background. Longitudinal investigations into the origins of adult essential hypertension have found elevated blood pressure in children to accurately track into adulthood, however the direct causes of essential hypertension in adolescence and adulthood remains unclear. Methods. We revisited 152 Peruvian adolescents from a birth cohort tracked from 0 to 30 months of age, and evaluated growth via monthly anthropometric measurements between 1995 and 1998, and obtained anthropometric and blood pressure measurements 11-14 years later. We used multivariable regression models to study the effects of infantile and childhood growth trends on blood pressure and central obesity in early adolescence. Results. In regression models adjusted for interim changes in weight and height, each 0.1 SD increase in weight for length from 0 to 5 months of age, and 1 SD increase from 6 to 30 months of age, was associated with decreased adolescent systolic blood pressure by 1.3 mm Hg (95% CI -2.4 to -0.1) and 2.5 mm Hg (95% CI -4.9 to 0.0), and decreased waist circumference by 0.6 (95% CI -1.1 to 0.0) and 1.2 cm (95% CI -2.3 to -0.1), respectively. Growth in infancy and early childhood was not significantly associated with adolescent waist-to-hip ratio. Conclusions. Rapid compensatory growth in early life has been posited to increase the risk of long-term cardiovascular morbidities such that nutritional interventions may do more harm than good. However, we found increased weight growth during infancy and early childhood to be associated with decreased systolic blood pressure and central adiposity in adolescence.

  12. Sleepiness and nocturnal hypoxemia in Peruvian men with obstructive sleep apnea

    PubMed Central

    de Castro, Jorge Rey; Mezones-Holguín, Edward

    2014-01-01

    Purpose To evaluate the intensity of nocturnal hypoxemia associated with sleepiness in Peruvian men with a diagnosis of obstructive sleep apnea (OSA). Methods We carried out a secondary data analysis based on a study which includes patients with OSA who were seen in a private hospital in Lima, Peru from 2006 to 2012. We included male adults who had polysomnographic recordings and who answered the Epworth sleepiness scale (ESE). The intensity of nocturnal hypoxemia (oxygen saturation ≤90 %) was classified in four new categories: 0, <1, 1 to 10 and >10 % total sleep time with nocturnal hypoxemia (NH). When the ESE score was higher than 10, we used the definitions presence or absence of sleepiness. We used Poisson regression models with robust variance to estimate crude and adjusted prevalence ratios (PR) for association between sleepiness and NH. Results 518 male patients with OSA were evaluated. Four hundred and fifty-two (87 %) patients had NH and 262 (51 %) had sleepiness. Of the 142 (27.4 %) patients who had >10 % total sleep time with NH, 98 (69.0 %) showed sleepiness and had a greater probability of sleepiness prevalence, with a crude PR of 1.82 (95 % CI 1.31–2.53). This association persisted in the multivariate models. Conclusions We found an association between NH and sleepiness. Only patients with the major intensity of NH (over 10 % of the total sleep time) had a greater probability of sleepiness. This suggests that sleepiness probably occurs after a chronic process and after overwhelming compensatory mechanisms. PMID:24249663

  13. Gold mining in the Peruvian Amazon: global prices, deforestation, and mercury imports.

    PubMed

    Swenson, Jennifer J; Carter, Catherine E; Domec, Jean-Christophe; Delgado, Cesar I

    2011-04-19

    Many factors such as poverty, ineffective institutions and environmental regulations may prevent developing countries from managing how natural resources are extracted to meet a strong market demand. Extraction for some resources has reached such proportions that evidence is measurable from space. We present recent evidence of the global demand for a single commodity and the ecosystem destruction resulting from commodity extraction, recorded by satellites for one of the most biodiverse areas of the world. We find that since 2003, recent mining deforestation in Madre de Dios, Peru is increasing nonlinearly alongside a constant annual rate of increase in international gold price (∼18%/yr). We detect that the new pattern of mining deforestation (1915 ha/year, 2006-2009) is outpacing that of nearby settlement deforestation. We show that gold price is linked with exponential increases in Peruvian national mercury imports over time (R(2) = 0.93, p = 0.04, 2003-2009). Given the past rates of increase we predict that mercury imports may more than double for 2011 (∼500 t/year). Virtually all of Peru's mercury imports are used in artisanal gold mining. Much of the mining increase is unregulated/artisanal in nature, lacking environmental impact analysis or miner education. As a result, large quantities of mercury are being released into the atmosphere, sediments and waterways. Other developing countries endowed with gold deposits are likely experiencing similar environmental destruction in response to recent record high gold prices. The increasing availability of satellite imagery ought to evoke further studies linking economic variables with land use and cover changes on the ground.

  14. Lead exposure from soil in Peruvian mining towns: a national assessment supported by two contrasting examples

    PubMed Central

    Bravo, Carolina; Gil, Vladimir; Sherpa, Shaky; Jack, Darby

    2012-01-01

    Abstract Objective To estimate the population of Peru living in the vicinity of active or former mining operations that could be exposed to lead from contaminated soil. Methods Geographic coordinates were compiled for 113 active mines, 138 ore processing plants and 3 smelters, as well as 7743 former mining sites. The population living within 5 km of these sites was calculated from census data for 2000. In addition, the lead content of soil in the historic mining town of Cerro de Pasco and around a recent mine and ore processing plant near the city of Huaral was mapped in 2009 using a hand-held X-ray fluorescence analyser. Findings Spatial analysis indicated that 1.6 million people in Peru could be living within 5 km of an active or former mining operation. Two thirds of the population potentially exposed was accounted for by 29 clusters of mining operations, each with a population of over 10 000 each. These clusters included 112 active and 3438 former mining operations. Soil lead levels exceeded 1200 mg/kg, a reference standard for residential soil, in 35 of 74 sites tested in Cerro de Pasco but in only 4 of 47 sites tested around the newer operations near Huaral. Conclusion Soil contamination with lead is likely to be extensive in Peruvian mining towns but the level of contamination is spatially far from uniform. Childhood exposure by soil ingestion could be substantially reduced by mapping soil lead levels, making this information public and encouraging local communities to isolate contaminated areas from children. PMID:23284193

  15. Cyclic 100-ka (glacial-interglacial) migration of subseafloor redox zonation on the Peruvian shelf

    PubMed Central

    Contreras, Sergio; Meister, Patrick; Liu, Bo; Prieto-Mollar, Xavier; Hinrichs, Kai-Uwe; Khalili, Arzhang; Ferdelman, Timothy G.; Kuypers, Marcel M. M.; Jørgensen, Bo Barker

    2013-01-01

    The coupling of subseafloor microbial life to oceanographic and atmospheric conditions is poorly understood. We examined diagenetic imprints and lipid biomarkers of past subseafloor microbial activity to evaluate its response to glacial-interglacial cycles in a sedimentary section drilled on the Peruvian shelf (Ocean Drilling Program Leg 201, Site 1229). Multiple and distinct layers of diagenetic barite and dolomite, i.e., minerals that typically form at the sulfate−methane transition (SMT), occur at much shallower burial depth than the present SMT around 30 meters below seafloor. These shallow layers co-occur with peaks of 13C-depleted archaeol, a molecular fossil of anaerobic methane-oxidizing Archaea. Present-day, non-steady state distributions of dissolved sulfate also suggest that the SMT is highly sensitive to variations in organic carbon flux to the surface shelf sediments that may lead to shoaling of the SMT. Reaction-transport modeling substantiates our hypothesis that shallow SMTs occur in response to cyclic sediment deposition with a high organic carbon flux during interglacials and a low organic carbon flux during glacial stages. Long diffusion distances expectedly dampen the response of deeply buried microbial communities to changes in sediment deposition and other oceanographic drivers over relatively short geological time scales, e.g., glacial-interglacial periods. However, our study demonstrates how dynamically sediment biogeochemistry of the Peru Margin has responded to glacial-interglacial change and how these changes are now preserved in the geological record. Such changes in subsurface biogeochemical zonation need to be taken into account to assess the role of the subseafloor biosphere in global element and redox cycling. PMID:24145422

  16. Gold Mining in the Peruvian Amazon: Global Prices, Deforestation, and Mercury Imports

    PubMed Central

    Swenson, Jennifer J.; Carter, Catherine E.; Domec, Jean-Christophe; Delgado, Cesar I.

    2011-01-01

    Many factors such as poverty, ineffective institutions and environmental regulations may prevent developing countries from managing how natural resources are extracted to meet a strong market demand. Extraction for some resources has reached such proportions that evidence is measurable from space. We present recent evidence of the global demand for a single commodity and the ecosystem destruction resulting from commodity extraction, recorded by satellites for one of the most biodiverse areas of the world. We find that since 2003, recent mining deforestation in Madre de Dios, Peru is increasing nonlinearly alongside a constant annual rate of increase in international gold price (∼18%/yr). We detect that the new pattern of mining deforestation (1915 ha/year, 2006–2009) is outpacing that of nearby settlement deforestation. We show that gold price is linked with exponential increases in Peruvian national mercury imports over time (R2 = 0.93, p = 0.04, 2003–2009). Given the past rates of increase we predict that mercury imports may more than double for 2011 (∼500 t/year). Virtually all of Peru's mercury imports are used in artisanal gold mining. Much of the mining increase is unregulated/artisanal in nature, lacking environmental impact analysis or miner education. As a result, large quantities of mercury are being released into the atmosphere, sediments and waterways. Other developing countries endowed with gold deposits are likely experiencing similar environmental destruction in response to recent record high gold prices. The increasing availability of satellite imagery ought to evoke further studies linking economic variables with land use and cover changes on the ground. PMID:21526143

  17. Demirjian's stages and Cameriere's third molar maturity index to estimate legal adult age in Peruvian population.

    PubMed

    Quispe Lizarbe, Roselhy Juliana; Solís Adrianzén, Christian; Quezada-Márquez, Milushka Miroslava; Galić, Ivan; Cameriere, Roberto

    2017-03-01

    To compare the accuracy of Demirjian's stages (DS) and Cameriere's third molar maturity index cut-off value (I3M<0.08) to estimate the age of majority on panoramic radiographs (OPTs) from the dental clinic of the Scientific University of the South (UCSUR), Lima, Peru. An observational cross-sectional study was conducted on the sample of 208 digital panoramic radiographs of patients aged 14-22years examined during 2015 in UCSUR. The left lower third molars were analyzed using Adobe Photoshop® CS6. An effectiveness of specific DS and I3M<0.08 was evaluated by using accurate classification, sensitivity, specificity, positive (LR+) and negative (LR-) likelihood ratios and Bayes post-test probability (p). Only G and H stages were practical for classify adults and minors in the tested sample, while I3M<0.08 showed the best performance in both sexes. For I3M<0.08, the accurate classification, sensitivity and specificity were 0.96, 0.96, 0.96 and 0.90, 0.84 and 0.95 in males and females, respectively. Values of LR+, LR- and p were 24.96, 0.04, 0.97 and 15.68, 0.17, 0.95 in males and females, respectively. The specific cut-off value of third molar maturity index (I3M<0.08) showed to be more accurate in discriminating adults and minors in Peruvian sample when a test with high sensitivity and specificity is required. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Deposits of the Peruvian Pisco Formation compared to layered deposits on Mars

    NASA Astrophysics Data System (ADS)

    Sowe, M.; Bishop, J. L.; Gross, C.; Walter, S.

    2013-09-01

    Deposits of the Peruvian Pisco Formation are morphologically similar to the mounds of Juventae Chasma at the equatorial region on Mars (Fig. 1). By analyzing these deposits, we hope to gain information about the environmental conditions that prevailed during sediment deposition and erosion, hence conditions that might be applicable to the Martian layered and hydrated deposits. Mariner 9 data of the Martian mid-latitudes have already shown evidence of the wind-sculptured landforms that display the powerful prevailing eolian regime [1]. In addition, [2] reported on similarities between Martian erosional landforms and those of the rainless coastal desert of central Peru from the Paracas peninsula to the Rio Ica. As indicated by similar erosional patterns, hyper-arid conditions and unidirectional winds must have dominated at least after deposition of the sediments, which are intermixed volcaniclastic materials and evaporate minerals at both locations. Likewise, variations in composition are displayed by alternating layers of different competence. The Pisco formation bears yardangs on siltstones, sandstones and clays with volcaniclastic admixtures [3] whereas the presence of sulphate minerals and the omnipresent mafic mineralogy has been reported for the layered mounds of Juventae Chasma equally [4]. Likewise, a volcanic airfall deposition and lacustrine formation have been proposed for the sulphate-rich deposits of Juventae Chasma [5,6]. In order to find out about potential spectral similarities, we performed a detailed spectral analysis of the surface by using LANDSAT and Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) VNIR/ SWIR data (visible to near-infrared and shortwave infrared region).

  19. Association Between Adherence to the Mediterranean Diet and Asthma in Peruvian Children.

    PubMed

    Rice, Jessica L; Romero, Karina M; Galvez Davila, Rocio M; Meza, Carla Tarazona; Bilderback, Andrew; Williams, D'Ann L; Breysse, Patrick N; Bose, Sonali; Checkley, William; Hansel, Nadia N

    2015-12-01

    Adherence to a Mediterranean diet pattern may be associated with lower asthma prevalence in children. We sought to corroborate these findings in Peruvian children. This case-control study included children of ages 9-19 years living in Lima, Peru. A food frequency questionnaire (FFQ) was completed and diet pattern was analyzed using a modified Mediterranean diet score (MDS). Primary analysis investigated the relationship between MDS and asthma status. Maternal education, age, sex, and body mass index category were included in multivariate model. Secondary outcomes included asthma control, forced expiratory volume in 1 s (FEV1), allergic rhinitis, and atopic status. 287 participants with asthma and 96 controls without asthma completed a FFQ. Mean age was 13.5 years. According to the asthma control test (ACT), 86 % of those with asthma were controlled (score >19). MDS scores ranged 6-18 (median 15). In adjusted analysis, being above the median MDS scores was associated with decreased odds of asthma [OR = 0.55, 95 % CI (0.33, 0.92), p = 0.02]. Among children whose mothers completed secondary education, being above the median MDS significantly decreased the odds of asthma [OR = 0.31, 95 % CI (0.14, 0.71), p < 0.01], whereas among those whose mothers did not complete secondary education there was no protective effect [OR = 0.86, 95 % CI (0.43, 1.7), p = 0.66]. There was no association between MDS scores and asthma control, FEV1, allergic rhinitis, or atopic status. Adherence to the Mediterranean diet was inversely associated with having asthma among children in Lima, Peru. This effect was strongest among children with better educated mothers.

  20. Lead exposure from soil in Peruvian mining towns: a national assessment supported by two contrasting examples.

    PubMed

    van Geen, Alexander; Bravo, Carolina; Gil, Vladimir; Sherpa, Shaky; Jack, Darby

    2012-12-01

    To estimate the population of Peru living in the vicinity of active or former mining operations that could be exposed to lead from contaminated soil. Geographic coordinates were compiled for 113 active mines, 138 ore processing plants and 3 smelters, as well as 7743 former mining sites. The population living within 5 km of these sites was calculated from census data for 2000. In addition, the lead content of soil in the historic mining town of Cerro de Pasco and around a recent mine and ore processing plant near the city of Huaral was mapped in 2009 using a hand-held X-ray fluorescence analyser. Spatial analysis indicated that 1.6 million people in Peru could be living within 5 km of an active or former mining operation. Two thirds of the population potentially exposed was accounted for by 29 clusters of mining operations, each with a population of over 10 000 each. These clusters included 112 active and 3438 former mining operations. Soil lead levels exceeded 1200 mg/kg, a reference standard for residential soil, in 35 of 74 sites tested in Cerro de Pasco but in only 4 of 47 sites tested around the newer operations near Huaral. Soil contamination with lead is likely to be extensive in Peruvian mining towns but the level of contamination is spatially far from uniform. Childhood exposure by soil ingestion could be substantially reduced by mapping soil lead levels, making this information public and encouraging local communities to isolate contaminated areas from children.

  1. Characteristics and Factors Associated With Antihypertensive Medication Use in Patients Attending Peruvian Health Facilities

    PubMed Central

    Mejia, Christian R; Failoc-Rojas, Virgilio E; Cervantes, Carmen; Aspajo, Antonio J; Leandro, Jesus Galileo; Cordova-De La Cruz, Jhomar; Charri, Julio C; García-Auqui, Kevin E; Coronel-Chucos, Lelis Gabriela; Justo-Pinto, Luz Delia; Mamani-Apaza, Marisol Stefanie; Paz-Campos, Neil Arón; Correa, Ricardo

    2017-01-01

    Introduction  Hypertension is a very common disease worldwide, and medication is needed to prevent its short-term and long-term complications. Our objective was to determine the characteristics and factors associated with antihypertensive medication use in patients attending Peruvian health facilities. Materials & Methods We performed a multicenter, cross-sectional study with secondary data. We obtained self-reported antihypertensive medication from patients attending health facilities in 10 departments of Peru. We looked for associations of the antihypertensive treatment according to sociopathological factors and obtained p values using generalized linear models. Results Of the 894 patients with hypertension, 61% (547) were women and 60% (503) were on antihypertensive treatment, of which 82% (389) had monotherapy and 52% (258) had recently taken their medication. Antihypertensive treatment was positively correlated with the patient's age (adjusted prevalence ratio [aPR]: 1.01; 95% confidence interval [CI]: 1.007 to 1.017; p value < 0.001), diabetes (aPR: 1.31; 95% CI: 1.11 to 1.55; p value = 0.001) and cardiovascular disease (aPR: 1.38; 95% CI: 1.26 to 1.51; p value < 0.001). Conversely, the frequency of antihypertensive treatment decreases with physical activity (aPR: 0.80; 95% CI: 0.70 to 0.92; p value = 0.001). Conclusion Patients who have comorbidities and advanced age are more likely to be on antihypertensive treatment. In contrast, patients with increased physical activity have a lower frequency of antihypertensive treatment. It is important to consider these factors for future preventive programs and to improve therapeutic compliance. PMID:28331773

  2. Cyclic 100-ka (glacial-interglacial) migration of subseafloor redox zonation on the Peruvian shelf.

    PubMed

    Contreras, Sergio; Meister, Patrick; Liu, Bo; Prieto-Mollar, Xavier; Hinrichs, Kai-Uwe; Khalili, Arzhang; Ferdelman, Timothy G; Kuypers, Marcel M M; Jørgensen, Bo Barker

    2013-11-05

    The coupling of subseafloor microbial life to oceanographic and atmospheric conditions is poorly understood. We examined diagenetic imprints and lipid biomarkers of past subseafloor microbial activity to evaluate its response to glacial-interglacial cycles in a sedimentary section drilled on the Peruvian shelf (Ocean Drilling Program Leg 201, Site 1229). Multiple and distinct layers of diagenetic barite and dolomite, i.e., minerals that typically form at the sulfate-methane transition (SMT), occur at much shallower burial depth than the present SMT around 30 meters below seafloor. These shallow layers co-occur with peaks of (13)C-depleted archaeol, a molecular fossil of anaerobic methane-oxidizing Archaea. Present-day, non-steady state distributions of dissolved sulfate also suggest that the SMT is highly sensitive to variations in organic carbon flux to the surface shelf sediments that may lead to shoaling of the SMT. Reaction-transport modeling substantiates our hypothesis that shallow SMTs occur in response to cyclic sediment deposition with a high organic carbon flux during interglacials and a low organic carbon flux during glacial stages. Long diffusion distances expectedly dampen the response of deeply buried microbial communities to changes in sediment deposition and other oceanographic drivers over relatively short geological time scales, e.g., glacial-interglacial periods. However, our study demonstrates how dynamically sediment biogeochemistry of the Peru Margin has responded to glacial-interglacial change and how these changes are now preserved in the geological record. Such changes in subsurface biogeochemical zonation need to be taken into account to assess the role of the subseafloor biosphere in global element and redox cycling.

  3. Peruvian Mental Health Reform: A Framework for Scaling-up Mental Health Services

    PubMed Central

    Toyama, Mauricio; Castillo, Humberto; Galea, Jerome T.; Brandt, Lena R.; Mendoza, María; Herrera, Vanessa; Mitrani, Martha; Cutipé, Yuri; Cavero, Victoria; Diez-Canseco, Francisco; Miranda, J. Jaime

    2017-01-01

    Background: Mental, neurological, and substance (MNS) use disorders are a leading cause of disability worldwide; specifically in Peru, MNS affect 1 in 5 persons. However, the great majority of people suffering from these disorders do not access care, thereby making necessary the improvement of existing conditions including a major rearranging of current health system structures beyond care delivery strategies. This paper reviews and examines recent developments in mental health policies in Peru, presenting an overview of the initiatives currently being introduced and the main implementation challenges they face. Methods: Key documents issued by Peruvian governmental entities regarding mental health were reviewed to identify and describe the path that led to the beginning of the reform; how the ongoing reform is taking place; and, the plan and scope for scale-up. Results: Since 2004, mental health has gained importance in policies and regulations, resulting in the promotion of a mental health reform within the national healthcare system. These efforts crystallized in 2012 with the passing of Law 29889 which introduced several changes to the delivery of mental healthcare, including a restructuring of mental health service delivery to occur at the primary and secondary care levels and the introduction of supporting services to aid in patient recovery and reintegration into society. In addition, a performance-based budget was approved to guarantee the implementation of these changes. Some of the main challenges faced by this reform are related to the diversity of the implementation settings, eg, isolated rural areas, and the limitations of the existing specialized mental health institutes to substantially grow in parallel to the scaling-up efforts in order to be able to provide training and clinical support to every region of Peru. Conclusion: Although the true success of the mental healthcare reform will be determined in the coming years, thus far, Peru has achieved a

  4. Peruvian Mental Health Reform: A Framework for Scaling-up Mental Health Services.

    PubMed

    Toyama, Mauricio; Castillo, Humberto; Galea, Jerome T; Brandt, Lena R; Mendoza, María; Herrera, Vanessa; Mitrani, Martha; Cutipé, Yuri; Cavero, Victoria; Diez-Canseco, Francisco; Miranda, J Jaime

    2017-01-22

    Mental, neurological, and substance (MNS) use disorders are a leading cause of disability worldwide; specifically in Peru, MNS affect 1 in 5 persons. However, the great majority of people suffering from these disorders do not access care, thereby making necessary the improvement of existing conditions including a major rearranging of current health system structures beyond care delivery strategies. This paper reviews and examines recent developments in mental health policies in Peru, presenting an overview of the initiatives currently being introduced and the main implementation challenges they face. Key documents issued by Peruvian governmental entities regarding mental health were reviewed to identify and describe the path that led to the beginning of the reform; how the ongoing reform is taking place; and, the plan and scope for scale-up. Since 2004, mental health has gained importance in policies and regulations, resulting in the promotion of a mental health reform within the national healthcare system. These efforts crystallized in 2012 with the passing of Law 29889 which introduced several changes to the delivery of mental healthcare, including a restructuring of mental health service delivery to occur at the primary and secondary care levels and the introduction of supporting services to aid in patient recovery and reintegration into society. In addition, a performance-based budget was approved to guarantee the implementation of these changes. Some of the main challenges faced by this reform are related to the diversity of the implementation settings, eg, isolated rural areas, and the limitations of the existing specialized mental health institutes to substantially grow in parallel to the scaling-up efforts in order to be able to provide training and clinical support to every region of Peru. Although the true success of the mental healthcare reform will be determined in the coming years, thus far, Peru has achieved a number of legal, policy and fiscal

  5. Infant feeding practices in the Peruvian Amazon: implications for programs to improve feeding.

    PubMed

    Lee, Gwenyth; Paredes Olortegui, Maribel; Rengifo Pinedo, Sylvia; Ambikapathi, Ramya; Peñataro Yori, Pablo; Kosek, Margaret; Caulfield, Laura E

    2014-09-01

    To characterize feeding practices in a community in the Peruvian Amazon and to consider how this information could be used to strengthen programs and policies designed to improve nutrition and reduce child malnutrition in vulnerable communities. Data from three structured questionnaires were combined to produce a comprehensive depiction of feeding in a sample of 246 infants from birth through 8 months of life in the community of Santa Clara de Nanay near Iquitos, Peru. Breastfeeding initiation practices, exclusive breastfeeding in the first 180 days of life, the introduction of solids, and complementary feeding practices from 6-8 months, were described and related to maternal, infant, and household characteristics, including food insecurity. The median duration of exclusive breastfeeding was 19 days. However, over the first 180 days of life, children were exclusively breastfed on 46.1% of days. Overall, 68.3% of infants received some semi-solid or solid food between 0-6 months and all had received semi-solids by the end of 8 months of age. The proportion of infants consuming a minimally acceptable (frequent and diverse) complementary diet was 2.9%, 7.9%, and 16.1% at 6, 7, and 8 months respectively. Although breastfeeding is nearly universal, promotion programs are needed in Santa Clara to 1) delay the introduction of plain water, other non-breast milk liquids, and semi-solid foods; 2) extend the period of exclusive breastfeeding; and 3) increase food diversity and the frequency of feeding during the period of complementary feeding. These results can be used to guide programs and policies to improve nutrition and reduce child malnutrition.

  6. Characteristics and Factors Associated With Antihypertensive Medication Use in Patients Attending Peruvian Health Facilities.

    PubMed

    Mejia, Christian R; Failoc-Rojas, Virgilio E; So, Edison; Cervantes, Carmen; Aspajo, Antonio J; Leandro, Jesus Galileo; Cordova-De La Cruz, Jhomar; Charri, Julio C; García-Auqui, Kevin E; Coronel-Chucos, Lelis Gabriela; Justo-Pinto, Luz Delia; Mamani-Apaza, Marisol Stefanie; Paz-Campos, Neil Arón; Correa, Ricardo

    2017-02-03

    Hypertension is a very common disease worldwide, and medication is needed to prevent its short-term and long-term complications. Our objective was to determine the characteristics and factors associated with antihypertensive medication use in patients attending Peruvian health facilities. We performed a multicenter, cross-sectional study with secondary data. We obtained self-reported antihypertensive medication from patients attending health facilities in 10 departments of Peru. We looked for associations of the antihypertensive treatment according to sociopathological factors and obtained p values using generalized linear models. Of the 894 patients with hypertension, 61% (547) were women and 60% (503) were on antihypertensive treatment, of which 82% (389) had monotherapy and 52% (258) had recently taken their medication. Antihypertensive treatment was positively correlated with the patient's age (adjusted prevalence ratio [aPR]: 1.01; 95% confidence interval [CI]: 1.007 to 1.017; p value < 0.001), diabetes (aPR: 1.31; 95% CI: 1.11 to 1.55; p value = 0.001) and cardiovascular disease (aPR: 1.38; 95% CI: 1.26 to 1.51; p value < 0.001). Conversely, the frequency of antihypertensive treatment decreases with physical activity (aPR: 0.80; 95% CI: 0.70 to 0.92; p value = 0.001). Patients who have comorbidities and advanced age are more likely to be on antihypertensive treatment. In contrast, patients with increased physical activity have a lower frequency of antihypertensive treatment. It is important to consider these factors for future preventive programs and to improve therapeutic compliance.

  7. Diarrheagenic Escherichia coli: Prevalence and Pathotype Distribution in Children from Peruvian Rural Communities.

    PubMed

    Acosta, Gonzalo J; Vigo, Natalia I; Durand, David; Riveros, Maribel; Arango, Sara; Zambruni, Mara; Ochoa, Theresa J

    2016-09-07

    Diarrheagenic Escherichia coli (DEC) are common pathogens of childhood gastrointestinal infections worldwide. To date, research tracking DEC has mainly been completed in urban areas. This study aims to determine the prevalence and pathotype distribution of DEC strains in children from rural Peruvian communities and to establish their association with malnutrition. In this prospective cohort, 93 children aged 6-13 months from rural communities of Urubamba (Andes) and Moyobamba (jungle) were followed for 6 months. Diarrheal and control stool samples were analyzed using multiplex real-time polymerase chain reaction to identify the presence of virulence genes of DEC strains. The overall isolation rate of DEC was 43.0% (352/820). Enteroaggregative E. coli (EAEC, 20.4%), enteropathogenic E. coli (EPEC, 14.2%), and diffusely aggregative E. coli (DAEC, 11.0%) were the most prevalent pathotypes. EAEC was more frequently found in Moyobamba samples (P < 0.01). EPEC was the only strain significantly more frequent in diarrheal than asymptomatic control samples (P < 0.01). DEC strains were more prevalent among younger children (aged 6-12 months, P < 0.05). A decline in height-for-age Z-score (HAZ) was observed in 75.7% of children overall. EAEC was more frequently isolated among children who had a greater HAZ decline (P < 0.05). In conclusion, DEC strains were frequently found in stool samples from children in rural communities of the highlands and jungle of Peru. In addition, children with a greater decline in their growth rate had higher EAEC isolation rates, highlighting the importance of this pathogen in child malnutrition. © The American Society of Tropical Medicine and Hygiene.

  8. Diarrheagenic Escherichia coli: Prevalence and Pathotype Distribution in Children from Peruvian Rural Communities

    PubMed Central

    Acosta, Gonzalo J.; Vigo, Natalia I.; Durand, David; Riveros, Maribel; Arango, Sara; Zambruni, Mara; Ochoa, Theresa J.

    2016-01-01

    Diarrheagenic Escherichia coli (DEC) are common pathogens of childhood gastrointestinal infections worldwide. To date, research tracking DEC has mainly been completed in urban areas. This study aims to determine the prevalence and pathotype distribution of DEC strains in children from rural Peruvian communities and to establish their association with malnutrition. In this prospective cohort, 93 children aged 6–13 months from rural communities of Urubamba (Andes) and Moyobamba (jungle) were followed for 6 months. Diarrheal and control stool samples were analyzed using multiplex real-time polymerase chain reaction to identify the presence of virulence genes of DEC strains. The overall isolation rate of DEC was 43.0% (352/820). Enteroaggregative E. coli (EAEC, 20.4%), enteropathogenic E. coli (EPEC, 14.2%), and diffusely aggregative E. coli (DAEC, 11.0%) were the most prevalent pathotypes. EAEC was more frequently found in Moyobamba samples (P < 0.01). EPEC was the only strain significantly more frequent in diarrheal than asymptomatic control samples (P < 0.01). DEC strains were more prevalent among younger children (aged 6–12 months, P < 0.05). A decline in height-for-age Z-score (HAZ) was observed in 75.7% of children overall. EAEC was more frequently isolated among children who had a greater HAZ decline (P < 0.05). In conclusion, DEC strains were frequently found in stool samples from children in rural communities of the highlands and jungle of Peru. In addition, children with a greater decline in their growth rate had higher EAEC isolation rates, highlighting the importance of this pathogen in child malnutrition. PMID:27382080

  9. Seismic properties of the Nazca oceanic crust in southern Peruvian subduction system

    NASA Astrophysics Data System (ADS)

    Kim, YoungHee; Clayton, Robert W.

    2015-11-01

    The horizontal Nazca slab, extending over a distance of ∼800 km along the trench is one of enigmatic features in Peruvian subduction zone. Increased buoyancy of the oceanic lithosphere alone due to the subduction of Nazca Ridge is insufficient to fully explain such a lengthy segment. We use data from the recent seismic experiment in southern Peru to find that the subduction-related hydration plays a major role in controlling shear wave velocities within the upper part of the oceanic crust and overlying materials. We observe substantial velocity reductions of ∼20-40% near the top plate interface along- and perpendicular-to the trench from ∼40-120 km depths. In particular, significant shear wave velocity reductions and subsequently higher P-to-S velocity ratio (exceeding 2.0) at the flat slab region suggest that the seismically probed layer is fluid-rich and mechanically weak. The dominant source of fluid comes from metasediments and subducted crust (Nazca Ridge). Long-term supply of fluid from the southward migrating Nazca Ridge provides additional buoyancy of the subducting oceanic lithosphere and also lowers the viscosity of the overlying mantle wedge to drive and sustain the flat plate segment of ∼800 km along the trench. Also, by comparing calculated seismic velocities with experimentally derived mineral physics data, we additionally provide mechanical constraints on the possible changes in frictional behavior across the subduction zone plate interface. Observed low seismic velocities in the seismogenic zone suggest a presence of low strength materials that may be explained by overpressured pore fluids (i.e., accreted sediment included in the subduction channel).

  10. Glacial-interglacial Variations of Molybdenum Isotopes in the Peruvian Oxygen Minimum Zone

    NASA Astrophysics Data System (ADS)

    Siebert, C.; Frank, M.; Scholz, F.

    2015-12-01

    Mo isotopes have been widely used as a tool to constrain redox-conditions during major global events such as the oxygenation of the oceans in the Precambrian and Cretaceous Ocean Anoxic Events. In addition, Mo isotopes have considerable, yet underexplored potential to quantitatively track local redox-variation at high resolution on shorter timescales. Here we present data from piston core M77/2-024-5 that was retrieved in the Peruvian oxygen minimum zone in the context of Collaborative Research Centre (SFB) 754 of the Deutsche Forschungs Gemeinschaft (DFG). The age model for this core is well constrained and the core covers the last 140 ka with a hiatus between 20 and 50 ky BP. The oxygen minimum zone along the Peru continental margin is thought to have been better ventilated and therefore less pronounced during glacial periods compared to interglacials. Concentrations of redox-sensitive trace elements show high-amplitude changes and indicate periods of strongly sulphidic conditions with high Mo fixation rate and oxygenated periods with limited Mo fixation (Scholz et al 2014). Mo isotopes do not show straightforward correlations with elemental redox tracers and are only weakly correlated with Mo/U and total organic carbon (TOC). However, Mo isotopes become significantly heavier around the last glacial maximum (Δ98Mo of 0.4 permil). The observed signatures indicate that the Mo isotope composition is dominated by changes in the operating Mo delivery mechanism, i.e. particulate transport versus molecular diffusion. Our results suggest that Mo isotopes can track local redox variation therefore adding to our understanding of this complex indicator for marine environmental change. Scholz et al., (2014), Nature Geosciences, Vol. 7, Pages 433-437

  11. Hotspots of Malaria Transmission in the Peruvian Amazon: Rapid Assessment through a Parasitological and Serological Survey.

    PubMed

    Rosas-Aguirre, Angel; Speybroeck, Niko; Llanos-Cuentas, Alejandro; Rosanas-Urgell, Anna; Carrasco-Escobar, Gabriel; Rodriguez, Hugo; Gamboa, Dionicia; Contreras-Mancilla, Juan; Alava, Freddy; Soares, Irene S; Remarque, Edmond; D Alessandro, Umberto; Erhart, Annette

    2015-01-01

    With low and markedly seasonal malaria transmission, increasingly sensitive tools for better stratifying the risk of infection and targeting control interventions are needed. A cross-sectional survey to characterize the current malaria transmission patterns, identify hotspots, and detect recent changes using parasitological and serological measures was conducted in three sites of the Peruvian Amazon. After full census of the study population, 651 participants were interviewed, clinically examined and had a blood sample taken for the detection of malaria parasites (microscopy and PCR) and antibodies against P. vivax (PvMSP119, PvAMA1) and P. falciparum (PfGLURP, PfAMA1) antigens by ELISA. Risk factors for malaria infection (positive PCR) and malaria exposure (seropositivity) were assessed by multivariate survey logistic regression models. Age-specific seroprevalence was analyzed using a reversible catalytic conversion model based on maximum likelihood for generating seroconversion rates (SCR, λ). SaTScan was used to detect spatial clusters of serology-positive individuals within each site. The overall parasite prevalence by PCR was low, i.e. 3.9% for P. vivax and 6.7% for P. falciparum, while the seroprevalence was substantially higher, 33.6% for P. vivax and 22.0% for P. falciparum, with major differences between study sites. Age and location (site) were significantly associated with P. vivax exposure; while location, age and outdoor occupation were associated with P. falciparum exposure. P. falciparum seroprevalence curves showed a stable transmission throughout time, while for P. vivax transmission was better described by a model with two SCRs. The spatial analysis identified well-defined clusters of P. falciparum seropositive individuals in two sites, while it detected only a very small cluster of P. vivax exposure. The use of a single parasitological and serological malaria survey has proven to be an efficient and accurate method to characterize the species

  12. [Gait speed and the appearance of neurocognitive disorders in older adults: Results of a Peruvian cohort].

    PubMed

    Parodi, José F; Nieto-Gutierrez, Wendy; Tellez, Walter A; Ventocilla-Gonzales, Iris; Runzer-Colmenares, Fernando M; Taype-Rondan, Alvaro

    2017-09-07

    The prevention and management of neurocognitive disorders (NCD) among older adults can be improved by early identification of risk factors such as walking speed. The objective of the study is to assess the association between gait speed and NCD onset in a population of Peruvian older adults. Cohort conducted in older adults who attended the geriatrics service of Naval Medical Center (Callao, Peru). During the baseline assessment, participants' gait speed was recorded. Subsequently, participants were followed-up annually for 5 years, with a mean of 21 months. NCD onset was defined as the occurrence of a score ≤24 points on the Mini Mental State Examination (screening test) during follow-up. The hazard ratios (HR) and their 95% confidence intervals (95% CI) were calculated using Cox regression. The study included 657 participants, with a mean age of 73.4±9.2 (SD) years, of whom 47.0% were male, 47.8% had a gait speed <0.8 m/s, and 20.1% developed NCD during the follow up. It was found that older adults who had gait speed <0.8 m/s at baseline were more likely to develop NCD than those who had a gait speed ≥0.8 m/s (adjusted HR=1.41, 95% CI=1.34-1.47). A longitudinal association was found between decreased gait speed and NCD onset, suggesting that gait speed could be useful to identify patients at risk of NCD onset. Copyright © 2017 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. Multiple norovirus infections in a birth cohort in a Peruvian Periurban community.

    PubMed

    Saito, Mayuko; Goel-Apaza, Sonia; Espetia, Susan; Velasquez, Daniel; Cabrera, Lilia; Loli, Sebastian; Crabtree, Jean E; Black, Robert E; Kosek, Margaret; Checkley, William; Zimic, Mirko; Bern, Caryn; Cama, Vitaliano; Gilman, Robert H

    2014-02-01

    Human noroviruses are among the most common enteropathogens globally, and are a leading cause of infant diarrhea in developing countries. However, data measuring the impact of norovirus at the community level are sparse. We followed a birth cohort of children to estimate norovirus infection and diarrhea incidence in a Peruvian community. Stool samples from diarrheal episodes and randomly selected nondiarrheal samples were tested by polymerase chain reaction for norovirus genogroup and genotype. Excretion duration and rotavirus coinfection were evaluated in a subset of episodes. Two hundred twenty and 189 children were followed to 1 and 2 years of age, respectively. By 1 year, 80% (95% confidence interval [CI], 75%-85%) experienced at least 1 norovirus infection and by 2 years, 71% (95% CI, 65%-77%) had at least 1 episode of norovirus-associated diarrhea. Genogroup II (GII) infections were 3 times more frequent than genogroup 1 (GI) infections. Eighteen genotypes were found; GII genotype 4 accounted for 41%. Median excretion duration was 34.5 days for GII vs 8.5 days for GI infection (P = .0006). Repeat infections by the same genogroup were common, but repeat infections by the same genotype were rare. Mean length-for-age z score at 12 months was lower among children with prior norovirus infection compared to uninfected children (coefficient: -0.33 [95% CI, -.65 to -.01]; P = .04); the effect persisted at 24 months. Norovirus infection occurs early in life and children experience serial infections with multiple genotypes, suggesting genotype-specific immunity. An effective vaccine would have a substantial impact on morbidity, but may need to target multiple genotypes.

  14. Remineralization and preservation of the Organic Matter (OM) in the Peruvian Oxygen Minimum Zone

    NASA Astrophysics Data System (ADS)

    Bretagnon, M.; Paulmier, A.; Garcon, V.; Dewitte, B.; Maes, C.; Campos, F.; Carrasco, E.; Coppola, L.; Depretz de Gesincourt, O.; Gojak, C.; Grelet, J.; Illig, S.; Leblond, N.; Lefevre, D.; Martinez, P.; Oschlies, A.; Panagiotopoulos, C.; Scouarnec, L.; Velazco, F.

    2016-02-01

    The intense surface production in the Eastern Boundary Upwelling Systems (EBUS), linked to the low subsurface ventilation, leads to the formation of the Oxygen Minimum Zone (OMZ). The degradation of Organic Matter (OM) by respiration or remineralization impacts climate (ocean carbon sequestration; greenhouse gases emission (e.g. N2O, CO2)) and ecosystems (nitrogen loss; toxic gas (e.g. H2S) production). Due to the O2 stress, OM fate is an OMZ key-issue. On one hand, the low O2 concentration would imply OM preservation, enhancing the export to the sediments. On the other hand, the intense bacteria activity would imply OM recycling. The Peruvian EBUS, one of the most productive systems with the shallowest oxycline, is the perfect case study to investigate both hypotheses. In order to study the particles fluxes and its variability, sediment traps in the oxycline (35 m) and OMZ core (150 m) were deployed on an instrumented moored line off Lima (12°S) in 2013-2014, as part of the AMOP project (Activities of research dedicated to the Minimum of Oxygen in the eastern Pacific).The particles proportion which reaches the deep trap allows to define mathematically a vertical transfer function, suggesting predominant remineralization and preservation configurations. Concerning OM quality, carbon and nitrogen fluxes are proportional to the matter fluxes, contrary to phosphorus and biogenic silica fluxes. The different configurations derived from the transfer function analysis in terms of both OM quantity and quality can mainly be linked to oxygenation conditions, with a potential remineralization predominance associated with O2 concentration at the oxycline higher than a threshold of 5 µmol/kg. Oxygenation events are alternately associated with a specific influence of SubTropical Water, more or less oxygenated (Surface (STSW) or Under (STUW), respectively).

  15. Tropical Timber Rush in Peruvian Amazonia: Spatial Allocation of Forest Concessions in an Uninventoried Frontier

    NASA Astrophysics Data System (ADS)

    Salo, Matti; Toivonen, Tuuli

    2009-10-01

    Land-use allocation has important implications for the conservation and management of tropical forests. Peru’s forestry regime has recently been reformed and more than 7 million ha has been assigned as forest concessions. This potentially has a drastic impact on the land-use practices and species composition of the assigned areas. Nevertheless, the environmental variation found within the concessions and the process applied to delimit them are poorly studied and documented. Thus, it is difficult to estimate the biological impacts of forestry activities in concessions or plan them sustainably. This paper reveals the characteristics of the current concession allocation in Loreto, Peruvian Amazonia, using environmental and access-related variables and compares the concessions to other major land-use assignments. The work draws on a number of data sets describing land-use, ecosystem diversity, and fluvial network in the region. According to our data, certain environment types such as relatively fertile Pebas soils are overrepresented in the concessions, while others, like floodplain forests, are underrepresented in comparison to other land-use assignments. Concessions also have less anthropogenic disturbance than other areas. Furthermore, concessions are located on average further from the river network than the other land-use assignments studied. We claim that forest classification based on productivity, soil fertility, accessibility, and biodiversity patterns is an achievable long-term goal for forest authorities in Peru, and in many other tropical countries. We present a rough design of a geographic information system incorporating environmental, logging, and access-related data that could be applied to approach this goal in Peru.

  16. Early child health in an informal settlement in the Peruvian Amazon.

    PubMed

    Lee, Gwenyth O; Paredes Olortegui, Maribel; Salmón-Mulanovich, Gabriela; Peñataro Yori, Pablo; Kosek, Margaret

    2016-10-12

    Informal settlements are common throughout the developing world. In Peru, land occupations, commonly "invasions" in Spanish, are a means by which the extremely poor attempt to obtain access to land. Here, we examine difference in child health between two communities in the Peruvian Amazon, one well-established and one newly formed by 'invasion', as captured incidentally by a prospective epidemiological cohort study. Between 2002 and 2006 a study designed to describe the epidemiology of pediatric enteric infections and child growth in a community-based setting enrolled 442 children in Santa Clara de Nanay, a community adjacent to the city of Iquitos, in Loreto, Peru. In early 2003, a land occupation, commonly called an "invasion" in Spanish, was organized by members of the Santa Clara community, and approximately 20 % of participating study families began occupying privately owned agricultural land adjacent to Santa Clara, thus forming the new community of La Union. Parents in families that chose to invade reported less education than parents in families that chose not to. Children in the new community experienced a higher incidence of diarrheal disease and non-specific fevers, although fewer helminth infections, than children who remained in the established community. At the time of the invasion, there were no differences in anthropometric status between the two groups; however children in the new community experienced greater progressive growth faltering over the course of the longitudinal study. Growth faltering in early childhood represents an enduring loss of human potential. Therefore, our data suggests the human cost of land invasion may be disproportionately borne by the youngest individuals. Innovative policy strategies may be needed to protect this vulnerable group.

  17. Iron deficiency, but not anemia, upregulates iron absorption in breast-fed peruvian infants.

    PubMed

    Hicks, Penni D; Zavaleta, Nelly; Chen, Zhensheng; Abrams, Steven A; Lönnerdal, Bo

    2006-09-01

    Iron absorption in adults is regulated by homeostatic mechanisms that decrease absorption when iron status is high. There are few data, however, regarding the existence of a similar homeostatic regulation in infants. We studied 2 groups of human milk-fed infants using (57)Fe (given as ferrous sulfate without any milk) and (58)Fe (given at the time of a breast-milk feeding) stable isotopes to determine whether healthy infants at risk for iron deficiency would regulate their iron absorption based on their iron status. We studied 20 Peruvian infants at 5-6 mo of age and 18 infants at 9-10 mo of age. We found no effect of infant hemoglobin concentration on iron absorption with 5-6 mo-old infants absorbing 19.2 +/- 2.1% and 9- to 10-mo-old infants absorbing 25.8 +/- 2.6% of the (57)Fe dose. For (58)Fe, 5- to 6-mo-old infants absorbed 42.6 +/- 5.0% and 9 to 10-mo-old infants absorbed 51.9 +/- 10.3%. Following log transformation, iron absorption from (57)Fe (r = -0.61, P = < 0.001) and (58)Fe (r = -0.61, P = < 0.001) were inversely correlated to serum ferritin (S-Ft). For both the (57)Fe and (58)Fe doses, infants with S-Ft <12 mg/L (n = 11) had significantly higher iron absorption than those with S-Ft >12 mg/L. We concluded that iron absorption in infants is related to iron status as assessed by serum ferritin but not hemoglobin concentration. Infants with low iron status upregulate iron absorption from breast milk at both 5-6 and 9-10 mo of age.

  18. Arc Interrupted: The birth, life, and death of the Peruvian flat slab

    NASA Astrophysics Data System (ADS)

    Wagner, Lara; Knezevic Antonijevic, Sanja; Kumar, Abhash; Beck, Susan; Long, Maureen; Zandt, George; Tavera, Hernando; Minaya, Estela

    2016-04-01

    The Peruvian flat slab is a unique natural laboratory for investigating the temporal evolution of flat slab subduction and its associated thermal, tectonic, and seismic implications. This is because the flat slab has been hypothesized to have first formed further north (at approximately the latitude of Lima, Peru), but broadened to the south over the past 11 Ma. This means that areas further to the north represent an older, more evolved flat slab setting, whereas the southernmost edge of the modern flat slab reflects conditions experienced by a newly formed flat slab. Here we present findings from a suite of recent temporary broadband seismic deployments that spanned this entire region. Results from intermediate depth earthquake locations, surface wave tomography (ballistic and ambient Rayleigh wave), and Rayleigh wave anisotropy all indicate that the flat slab did indeed first form further to the north and broadened to the south, along with the southward migration of the Nazca ridge. Subsequently, a trench-parallel tear developed in the older portions of the flat slab north of the ridge, resulting in a resumption of normal subduction geometry where once a flat slab had existed. This tear allows for an interchange of mantle material from beneath the slab to the south to above the slab to the north. This mantle flow has significant thermal implications, both beneath the flat slab and in the lower continental crust located above the relatively newly formed tear. Our results provide unique constraints on the thermal and tectonic evolution of this unusual subduction geometry that may help us to understand better subduction zone processes everywhere.

  19. [Health and nutrition of indigenous and nonindigenous children in the Peruvian Amazon].

    PubMed

    Díaz, Adrián; Arana, Ana; Vargas-Machuca, Rocío; Antiporta, Daniel

    2015-07-01

    Evaluate the nutritional status of indigenous and nonindigenous children under 5 in two provinces in the Peruvian Amazon. . Descriptive cross-sectional representative study of families with children under 5 in the provinces of Bagua and Condorcanqui in Peru. The study consisted of an interview with the child's or children's mother or caregiver, anthropometric assessment, capillary hemoglobin measurement, screening for intestinal parasites in children under 5, access to health services, history of acute respiratory infections and acute diarrheal diseases, socioeconomic status, and intake of inadequately iodized salt. Using generalized linear methods, the determinants of chronic malnutrition and anemia in children were identified in each study population. . A total of 986 families and 1 372 children were assessed. The prevalence of chronic malnutrition was higher in the indigenous population than in the nonindigenous population (56.2% versus 21.9%); likewise for anemia (51.3% versus 40.9%). The determinants of chronic malnutrition in the two populations differed. In the indigenous population, the main determinants were an age of more than 36 months (OR 2.21; CI95% 1.61-3.04) and substandard housing (OR 2.9; CI95% 1.19-7.11), while in the non-indigenous population, they were extreme poverty (OR 2.31; IC95% 1.50-3.55) and institutional birth (OR 3.1; IC95% 2.00-4.83). There are marked gaps between the indigenous population and the nonindigenous population in terms of living conditions, access to health services, and the nutritional status of children under 5. Particular attention should be paid to the indigenous population to improve the way state programs and services are delivered in these contexts.

  20. Randomized Controlled Trial of Lactoferrin for Prevention of Sepsis in Peruvian Neonates <2500 Grams

    PubMed Central

    Ochoa, Theresa J.; Zegarra, Jaime; Cam, Luis; Llanos, Raul; Pezo, Alonso; Cruz, Karen; Zea-Vera, Alonso; Cárcamo, Cesar; Campos, Miguel; Bellomo, Sicilia

    2015-01-01

    Background Lactoferrin (LF) is a broad-spectrum antimicrobial and immunomodulatory milk glycoprotein. Objective To determine the effect of bovine LF on the prevention of the first episode of late-onset sepsis in Peruvian infants. Methods We conducted a pilot randomized placebo-controlled double blind study in infants with a birth weight <2500g in three Neonatal Units in Lima. Patients were randomized to receive bovine LF 200mg/kg/day or placebo for four weeks. Results 190 neonates with a birth weight of 1591±408g and a gestational age of 32.1±2.6wks were enrolled. Overall, 33 clinically-defined first late-onset sepsis events occurred. The cumulative sepsis incidence in the LF group was 12/95(12.6%) vs. 21/95(22.1%) in the placebo group, and 20% (8/40) vs. 37.5% (15/40) for infants ≤1500g. The hazard ratio of LF, after adjustment by birth weight, was 0.507 (95% CI, 0.249 to 1.034). There were 4 episodes of culture-proven sepsis in the LF group vs. 4 in the placebo group. Considering that children did not received the intervention until the start of oral or tube feeding, we ran a secondary exploratory analysis using time since the start of the treatment; in this model, LF achieved significance. There were no serious adverse events attributable to the intervention. Conclusions Overall sepsis occurred less frequently in the LF group than in the control group. Although the primary outcome did not reach statistical significance, the confidence interval is suggestive of an effect that justifies a larger trial. PMID:25973934

  1. Allocating Logging Rights in Peruvian Amazonia—Does It Matter to Be Local?

    PubMed Central

    Salo, Matti; Helle, Samuli; Toivonen, Tuuli

    2011-01-01

    Background The fate of tropical forests is a global concern, yet many far-reaching decisions affecting forest resources are made locally. We explore allocation of logging rights using a case study from Loreto, Peruvian Amazonia, where millions of hectares of tropical rainforest were offered for concession in a competitive tendering process that addressed issues related to locality. Methodology/Principal Findings After briefly presenting the study area and the tendering process, we identify and define local and non-local actors taking part in the concession process. We then analyse their tenders, results of the tendering, and attributes of the concession areas. Our results show that there was more offer than demand for concession land in the tendering. The number of tenders the concession areas received was related to their size and geographic location in relation to the major cities, but not to their estimated timber volumes or median distances from transport routes. Small and Loreto-based actors offered lower yearly area-based fees compared to larger ones, but the offers did not significantly affect the results of the tenders. Local experience in the form of logging history or residence near the solicited concession areas, as well as being registered in the region of Loreto, improved the success of the tenders. Conclusions/Significance The allocation process left a considerable number of forest areas under the management of small and local actors, and if Peru is to reach its goal of zero deforestation rate by safeguarding 75 per cent of its forests by 2020, the small and the local actors need to be integrated to the forest regime as important constituents of its legitimacy. PMID:21589922

  2. Seismic properties of the Nazca oceanic crust in southern Peruvian subduction system

    NASA Astrophysics Data System (ADS)

    Kim, Y.; Clayton, R. W.

    2015-12-01

    The horizontal Nazca slab, extending over a distance of ~800 km along the trench is one of enigmatic features in Peruvian subduction zone. Increased buoyancy of the oceanic lithosphere alone due to the subduction of Nazca Ridge is insufficient to fully explain such a lengthy segment. We use data from the recent seismic experiment in southern Peru to find that the subduction-related hydration plays a major role in controlling shear wave velocities within the upper part of the oceanic crust and overlying materials. We observe substantial velocity reductions of ~20-40% near the top plate interface along- and perpendicular-to the trench from ~40-120 km depths. In particular, significant shear wave velocity reductions and subsequently higher P-to-S velocity ratio (exceeding 2.0) at the flat slab region suggest that the seismically probed layer is fluid-rich and mechanically weak. The dominant source of fluid comes from metasediments and subducted crust (Nazca Ridge). Long-term supply of fluid from the southward migrating Nazca Ridge provides additional buoyancy of the subducting oceanic lithosphere and also lowers the viscosity of the overlying mantle wedge to drive and sustain the flat plate segment of ~800 km along the trench. Also, by comparing calculated seismic velocities with experimentally derived mineral physics data, we additionally provide mechanical constraints on the possible changes in frictional behavior across the subduction zone plate interface. Observed low seismic velocities in the seismogenic zone suggest a presence of low strength materials that may be explained by overpressured pore fluids (i.e., accreted sediment included in the subduction channel).

  3. [Prevalence of burnout syndrome in peruvian physicians and nurses, ENSUSALUD 2014].

    PubMed

    Maticorena-Quevedo, Jesús; Beas, Renato; Anduaga-Beramendi, Alexander; Mayta-Tristán, Percy

    2016-06-01

    Objectives To estimate the prevalence of burnout syndrome (BOS) in Peruvian physicians and nurses in 2014 according to different cutoff points established in the literature. Materials and methods This was a cross-sectional and descriptive study based on the National Survey on User Satisfaction of Health Services for 2014 (ENSUSALUD-2014), which features two-stage probability sampling. BOS was identified by the Maslach Burnout Inventory-Human Services Survey (MBI-HSS) using different cutoff points to establish prevalence, including default values, terciles, and quartiles. Results Of the 5062 health professionals, 62.3% were women, 44.0% were physicians, 46.0% belonged to the MINSA, and 23.1% worked in Lima. The overall BOS prevalence was 2.8% (95% CI, 2.4-3.2), when default values were used; the prevalence was 7.9% (95% CI, 7.3-8.6) when quartiles were used as cutoff points and 12.5% (95% CI, 11.4-13.6) when terciles were used as cutoff points. The prevalence was higher in doctors than in nurses, regardless of the cutoff point used (3.7% vs. 2.1% using default values, 10.2 vs. 6.1% using quartiles, and 16.2 vs. 9.5% using terciles). Conclusions The prevalence of BOS in health workers differs within the same population when different cutoff points are used. The use of default values is recommended by the instrument author until specific cut-points for our country are obtained.

  4. Big catch, little sharks: Insight into Peruvian small-scale longline fisheries

    PubMed Central

    Doherty, Philip D; Alfaro-Shigueto, Joanna; Hodgson, David J; Mangel, Jeffrey C; Witt, Matthew J; Godley, Brendan J

    2014-01-01

    Shark take, driven by vast demand for meat and fins, is increasing. We set out to gain insights into the impact of small-scale longline fisheries in Peru. Onboard observers were used to document catch from 145 longline fishing trips (1668 fishing days) originating from Ilo, southern Peru. Fishing effort is divided into two seasons: targeting dolphinfish (Coryphaena hippurus; December to February) and sharks (March to November). A total of 16,610 sharks were observed caught, with 11,166 identified to species level. Of these, 70.6% were blue sharks (Prionace glauca), 28.4% short-fin mako sharks (Isurus oxyrinchus), and 1% were other species (including thresher (Alopias vulpinus), hammerhead (Sphyrna zygaena), porbeagle (Lamnus nasus), and other Carcharhinidae species (Carcharhinus brachyurus, Carcharhinus falciformis, Galeorhinus galeus). Mean ± SD catch per unit effort of 33.6 ± 10.9 sharks per 1000 hooks was calculated for the shark season and 1.9 ± 3.1 sharks per 1000 hooks were caught in the dolphinfish season. An average of 83.7% of sharks caught (74.7% blue sharks; 93.3% mako sharks) were deemed sexually immature and under the legal minimum landing size, which for species exhibiting k-selected life history traits can result in susceptibility to over exploitation. As these growing fisheries operate along the entire Peruvian coast and may catch millions of sharks per annum, we conclude that their continued expansion, along with ineffective legislative approaches resulting in removal of immature individuals, has the potential to threaten the sustainability of the fishery, its target species, and ecosystem. There is a need for additional monitoring and research to inform novel management strategies for sharks while maintaining fisher livelihoods. PMID:25360274

  5. Big catch, little sharks: Insight into Peruvian small-scale longline fisheries.

    PubMed

    Doherty, Philip D; Alfaro-Shigueto, Joanna; Hodgson, David J; Mangel, Jeffrey C; Witt, Matthew J; Godley, Brendan J

    2014-06-01

    Shark take, driven by vast demand for meat and fins, is increasing. We set out to gain insights into the impact of small-scale longline fisheries in Peru. Onboard observers were used to document catch from 145 longline fishing trips (1668 fishing days) originating from Ilo, southern Peru. Fishing effort is divided into two seasons: targeting dolphinfish (Coryphaena hippurus; December to February) and sharks (March to November). A total of 16,610 sharks were observed caught, with 11,166 identified to species level. Of these, 70.6% were blue sharks (Prionace glauca), 28.4% short-fin mako sharks (Isurus oxyrinchus), and 1% were other species (including thresher (Alopias vulpinus), hammerhead (Sphyrna zygaena), porbeagle (Lamnus nasus), and other Carcharhinidae species (Carcharhinus brachyurus, Carcharhinus falciformis, Galeorhinus galeus). Mean ± SD catch per unit effort of 33.6 ± 10.9 sharks per 1000 hooks was calculated for the shark season and 1.9 ± 3.1 sharks per 1000 hooks were caught in the dolphinfish season. An average of 83.7% of sharks caught (74.7% blue sharks; 93.3% mako sharks) were deemed sexually immature and under the legal minimum landing size, which for species exhibiting k-selected life history traits can result in susceptibility to over exploitation. As these growing fisheries operate along the entire Peruvian coast and may catch millions of sharks per annum, we conclude that their continued expansion, along with ineffective legislative approaches resulting in removal of immature individuals, has the potential to threaten the sustainability of the fishery, its target species, and ecosystem. There is a need for additional monitoring and research to inform novel management strategies for sharks while maintaining fisher livelihoods.

  6. Use of filter papers to determine seroprevalence of Toxoplasma gondii among hunted ungulates in remote Peruvian Amazon.

    PubMed

    Aston, Emily J; Mayor, Pedro; Bowman, Dwight D; Mohammed, Hussni O; Liotta, Janice L; Kwok, Oliver; Dubey, J P

    2014-04-01

    Toxoplasmosis is a zoonosis caused by the protozoan Toxoplasma gondii, and it is found worldwide. To determine whether ungulates are reservoirs of T. gondii in an isolated and remote region of the northeastern Peruvian Amazon, antibodies to T. gondii were determined in 5 species of ungulates by the modified agglutination test (MAT). These animals were hunted by subsistence hunters along the Yavarí-Mirín River, in the northeastern Peruvian Amazon. Blood samples were collected by hunters on filter papers. For determination of T. gondii antibodies, blood was eluted from filter papers, and a titer of 1:25 was considered indicative of exposure to T. gondii. Antibodies to T. gondii were found in 26 (31.0%) peccaries (Pecari tajacu, Tayassu pecari), six (17.1%) brocket deer (Mazama americana, Mazama gouazoubira), and four (40.0%) lowland tapir (Tapirus terrestris). We also introduced a modification to the MAT protocol that allows the extraction of fluid samples from several types of laboratory-grade filter paper, thus enabling researchers to easily adapt their approaches to the materials presented to them.

  7. Micro-epidemiology and spatial heterogeneity of P. vivax parasitaemia in riverine communities of the Peruvian Amazon: A multilevel analysis.

    PubMed

    Carrasco-Escobar, Gabriel; Gamboa, Dionicia; Castro, Marcia C; Bangdiwala, Shrikant I; Rodriguez, Hugo; Contreras-Mancilla, Juan; Alava, Freddy; Speybroeck, Niko; Lescano, Andres G; Vinetz, Joseph M; Rosas-Aguirre, Angel; Llanos-Cuentas, Alejandro

    2017-08-14

    Malaria has steadily increased in the Peruvian Amazon over the last five years. This study aimed to determine the parasite prevalence and micro-geographical heterogeneity of Plasmodium vivax parasitaemia in communities of the Peruvian Amazon. Four cross-sectional active case detection surveys were conducted between May and July 2015 in four riverine communities in Mazan district. Analysis of 2785 samples of 820 individuals nested within 154 households for Plasmodium parasitaemia was carried out using light microscopy and qPCR. The spatio-temporal distribution of Plasmodium parasitaemia, dominated by P. vivax, was shown to cluster at both household and community levels. Of enrolled individuals, 47% had at least one P. vivax parasitaemia and 10% P. falciparum, by qPCR, both of which were predominantly sub-microscopic and asymptomatic. Spatial analysis detected significant clustering in three communities. Our findings showed that communities at small-to-moderate spatial scales differed in P. vivax parasite prevalence, and multilevel Poisson regression models showed that such differences were influenced by factors such as age, education, and location of households within high-risk clusters, as well as factors linked to a local micro-geographic context, such as travel and occupation. Complex transmission patterns were found to be related to human mobility among communities in the same micro-basin.

  8. Use of filter papers to determine seroprevalence of Toxoplasma gondii among hunted ungulates in remote Peruvian Amazon☆

    PubMed Central

    Aston, Emily J.; Mayor, Pedro; Bowman, Dwight D.; Mohammed, Hussni O.; Liotta, Janice L.; Kwok, Oliver; Dubey, J.P.

    2013-01-01

    Toxoplasmosis is a zoonosis caused by the protozoan Toxoplasma gondii, and it is found worldwide. To determine whether ungulates are reservoirs of T. gondii in an isolated and remote region of the northeastern Peruvian Amazon, antibodies to T. gondii were determined in 5 species of ungulates by the modified agglutination test (MAT). These animals were hunted by subsistence hunters along the Yavarí-Mirín River, in the northeastern Peruvian Amazon. Blood samples were collected by hunters on filter papers. For determination of T. gondii antibodies, blood was eluted from filter papers, and a titer of 1:25 was considered indicative of exposure to T. gondii. Antibodies to T. gondii were found in 26 (31.0%) peccaries (Pecari tajacu, Tayassu pecari), six (17.1%) brocket deer (Mazama americana, Mazama gouazoubira), and four (40.0%) lowland tapir (Tapirus terrestris). We also introduced a modification to the MAT protocol that allows the extraction of fluid samples from several types of laboratory-grade filter paper, thus enabling researchers to easily adapt their approaches to the materials presented to them. PMID:24918073

  9. Morningness/Eveningness Chronotype, Poor Sleep Quality, and Daytime Sleepiness in Relation to Common Mental Disorders among Peruvian College Students

    PubMed Central

    Rose, Deborah; Gelaye, Bizu; Sanchez, Sixto; Castañeda, Benjamín; Sanchez, Elena; Yanez, N David; Williams, Michelle A.

    2014-01-01

    The study was designed to investigate the association between sleep disturbances and common mental disorders (CMDs) among Peruvian college students. A total of 2,538 undergraduate students completed a self-administered questionnaire to gather information about sleep characteristics, socio-demographic and lifestyle data. Evening chronotype, sleep quality, and daytime sleepiness were assessed using the Horne and Ostberg Morningess-Eveningeness Questionnaire (MEQ), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS). Presence of CMDs was evaluated using the General Health Questionnaire (GHQ-12). Logistic regression procedures were used to examine the associations of sleep disturbances with CMDs while accounting for possible confounding factors. Overall, 33.4% of the participants had prevalent CMDs (39.2% among females and 24.4% among males). In multivariable adjusted logistic models, those with evening chronotype (OR=1.43; 95% CI 1.00–2.05), poor sleep quality (OR=4.50; 95%CI 3.69–5.49) and excessive daytime sleepiness (OR=1.68; 95% CI 1.41–2.01) were at a relative increased odds of CMDs compared to those without sleep disturbances. In conclusion, we found strong associations between sleep disturbances and CMDs among Peruvian college students. Early education and preventative interventions designed to improve sleep habits may effectively alter the possibility of developing CMDs among young adults. PMID:25162477

  10. Morningness/eveningness chronotype, poor sleep quality, and daytime sleepiness in relation to common mental disorders among Peruvian college students.

    PubMed

    Rose, Deborah; Gelaye, Bizu; Sanchez, Sixto; Castañeda, Benjamín; Sanchez, Elena; Yanez, N David; Williams, Michelle A

    2015-01-01

    The study was designed to investigate the association between sleep disturbances and common mental disorders (CMDs) among Peruvian college students. A total of 2538 undergraduate students completed a self-administered questionnaire to gather information about sleep characteristics, sociodemographic, and lifestyle data. Evening chronotype, sleep quality, and daytime sleepiness were assessed using the Horne and Ostberg morningness-eveningness questionnaire, Pittsburgh Sleep Quality Index, and Epworth Sleepiness Scale, respectivelty. Presence of CMDs was evaluated using the General Health Questionnaire. Logistic regression procedures were used to examine the associations of sleep disturbances with CMDs while accounting for possible confounding factors. Overall, 32.9% of the participants had prevalent CMDs (39.3% among females and 24.4% among males). In multivariable-adjusted logistic models, those with evening chronotype (odds ratios (OR) = 1.43; 95% CI 1.00-2.05), poor sleep quality (OR = 4.50; 95% CI 3.69-5.49), and excessive daytime sleepiness (OR = 1.68; 95% CI 1.41-2.01) were at a relative increased odds of CMDs compared with those without sleep disturbances. In conclusion, we found strong associations between sleep disturbances and CMDs among Peruvian college students. Early education and preventative interventions designed to improve sleep habits may effectively alter the possibility of developing CMDs among young adults.

  11. Screening of Peruvian Medicinal Plants for Tyrosinase Inhibitory Properties: Identification of Tyrosinase Inhibitors in Hypericum laricifolium Juss.

    PubMed

    Quispe, Yanymee Nimesia Guillen; Hwang, Seung Hwan; Wang, Zhiqiang; Lim, Soon Sung

    2017-03-04

    Tyrosinase inhibitors are of far-ranging importance in cosmetics, medicinal products, and food industries. Peru is a diverse country with a wide variety of plants that may contain excellent anti-tyrosinase inhibitors. In the present study, the tyrosinase inhibitory properties of 50 medicinal plant extracts from Peru were investigated using tyrosinase assay. Among plant extracts, those that showed an inhibition rate >50% were Hypericum laricifolium Juss., Taraxacum officinaleF.H.Wigg., and Muehlenbeckia vulcanicaMeisn., with H. laricifolium Juss. showing the greatest anti-tyrosinase activity. Although H. laricifolium Juss. has been widely used as a medicinal plant by Peruvians, little is known regarding its bioactive components and effects on tyrosinase activity. For this reason, we attempted to discover tyrosinase inhibitors in H. laricifolium Juss. for the first time. The bioactive components were separated by Sephadex LH-20 chromatography and eluted with 100% methanol. Eight compounds were discovered and characterized by high-performance liquid chromatography coupled with diode array detection (HPLC-DAD): protocatechuic acid, p-hydroxybenzoic acid, chlorogenic acid, vanilic acid, caffeic acid, kaempferol 3-O-glucuronide, quercetin, and kaempferol. In addition, the concentration of these compounds required for 50% inhibition (IC50) of tyrosinase activity were evaluated. Quercetin exhibited the strongest tyrosinase inhibition (IC50 14.29 ± 0.3 μM). Therefore, the Peruvian plant H. laricifolium Juss. could be a novel source for anti-tyrosinase activity.

  12. Efficacy and Effectiveness of Mefloquine and Artesunate Combination Therapy for Uncomplicated Plasmodium falciparum Malaria in the Peruvian Amazon

    PubMed Central

    de Oliveira, Alexandre Macedo; Chavez, Jorge; de Leon, Gabriel Ponce; Durand, Salomon; Arrospide, Nancy; Roberts, Jacquelin; Cabezas, Cesar; Marquiño, Wilmer

    2011-01-01

    We evaluated the efficacy and effectiveness of mefloquine (MQ) plus artesunate (AS) to treat patients with uncomplicated malaria in the Peruvian Amazon Basin in April 2005–March 2006. Patients ≥ 1 year of age with fever (axillary temperature ≥ 37.5°C) or history of fever and Plasmodium falciparum monoinfection were included. Patients received antimalarial treatment with MQ (12.5 mg/kg/day for two days) and AS (4.0 mg/kg/day for three days) either by directly observed therapy or without directly observed therapy. After a 28-day follow-up, treatment efficacy and effectiveness were assessed on the basis of clinical and parasitologic outcomes. Ninety-six patients were enrolled in each study group; nine patients were lost to follow-up. All patients, except for one in the observed group, demonstrated adequate clinical and parasitologic response; none had detectable parasitemia on day 3. The efficacy of MQ + AS efficacy was 98.9% (95% confidence interval = 94.1–100.0%) and the effectiveness was 100.0% (95% confidence interval = 95.9–100.0%). Our study shows that MQ + AS is highly efficacious in the Peruvian Amazon. PMID:21896825

  13. Clinical and molecular studies reveal a PSEN1 mutation (L153V) in a Peruvian family with early-onset Alzheimer's disease.

    PubMed

    Cornejo-Olivas, Mario R; Yu, Chang-En; Mazzetti, Pilar; Mata, Ignacio F; Meza, Maria; Lindo-Samanamud, Saul; Leverenz, James B; Bird, Thomas D

    2014-03-20

    Presenilin 1 (PSEN1) gene mutations are found in 30-70% of familial early-onset Alzheimer disease (EOAD) cases (onset <60 years). Prevalence of these mutations is highly variable including ethnic differences worldwide. No Peruvian kindred with familial AD (FAD) have been described. Standardized clinical evaluation and cognitive assessment were completed in a Peruvian family with severe EOAD. Clinical course was characterized by very early onset (before age 35 years), progressive cognitive impairment with early memory loss, spatial disorientation and executive dysfunction. We sequenced all exons of PSEN1 in the proband and identified a c.475C>G DNA change resulting in a p.L153V missense mutation in the transmembrane domain 2 of the gene. This mutation is also present in the three additional affected siblings but not in a non-affected family member consistent with segregation of this mutation with the disease. This is the first report of a Peruvian family affected with EOAD associated with a PSEN1 mutation. This same mutation has been reported previously in English and French families, but a novel variants very close to the mutation and ancestry informative markers analysis suggests the mutation might be of Amerindian or African origin in this Peruvian family.

  14. Changes in soil physical and chemical properties in long term improved natural and traditional agroforestry management systems of cacao genotypes in Peruvian Amazon

    USDA-ARS?s Scientific Manuscript database

    Traditional slash and burn agriculture practiced in the Peruvian Amazon region is leading to soil degradation and deforestation of native forest flora. The only way to stop such destructive processes is through the adoptation of sustainable alternatives such as growing crops in agroforestry systems....

  15. Trophic structure of the Peruvian marine ecosystem in 2000-2006: Insights on the effects of management scenarios for the hake fishery using the IBM trophic model Osmose

    NASA Astrophysics Data System (ADS)

    Marzloff, Martin; Shin, Yunne-Jai; Tam, Jorge; Travers, Morgane; Bertrand, Arnaud

    2009-01-01

    The individual-based trophic model Osmose is applied to the upwelling marine ecosystem off the coast of Peru. The dynamics and life cycle of eight major species of the Peruvian marine ecosystem are explicitly considered in the model. Reference simulations provide an overview of the trophic structure of the Peruvian ecosystem during the period 2000-2006. Results of model calibration and simulations are discussed in the light of current empirical knowledge on the trophic functioning of the Peruvian ecosystem and are compared to outputs obtained recently using the trophic model Ecopath. The impacts on the ecosystem of restoration plans for the depleted hake ( Merluccius gayi peruanus) population are explored through two management scenarios: a) a long term reduction of fishing effort targeting hake and b) a moratorium on the hake fishery. The simulations help better understand the recent failure of a 20 month hake moratorium and provide long-term strategic support to ecosystem-based management. Limits of our approach are discussed and recommendations are detailed for future developments of the Osmose model and ecosystem approach to fishery management in the Peruvian context.

  16. Intercultural Education and Literacy: An Ethnographic Study of Indigenous Knowledge and Learning in the Peruvian Amazon. Studies in Written Language and Literacy, Volume 7.

    ERIC Educational Resources Information Center

    Aikman, Sheila

    This book examines indigenous education in South America, focusing on the development of intercultural education and on an ethnographic study of educational processes and change among the Arakmbut people of the Peruvian Amazon. The Arakmbut are one of seven Harakmbut-speaking peoples who live in the Department of Madre de Dios in southeastern…

  17. Curriculum Reform and the Displacement of Knowledge in Peruvian Rural Secondary Schools: Exploring the Unintended Local Consequences of Global Education Policies

    ERIC Educational Resources Information Center

    Balarin, Maria; Benavides, Martin

    2010-01-01

    This paper draws attention to processes of policy implementation in developing contexts, and to the unintended consequences of education policies that follow international policy scripts without enough consideration of local histories and cultures. Drawing on a study of teaching practices in Peruvian rural secondary schools after a period of…

  18. Clinical and Molecular Studies Reveal a PSEN1 Mutation (L153V) in a Peruvian Family with Early-Onset Alzheimer's Disease

    PubMed Central

    Cornejo-Olivas, Mario R.; Yu, Chang-En; Mazzetti, Pilar; Mata, Ignacio F.; Meza, Maria; Lindo-Samanamud, Saul; Leverenz, James B.; Bird, Thomas D.

    2014-01-01

    Presenilin 1 (PSEN1) gene mutations are found in 30 to 70% of familial early onset Alzheimer disease (EOAD) cases (onset <60 years). Prevalence of these mutations is highly variable including ethnic differences worldwide. No Peruvian kindred with familial AD (FAD) have been described. Standardized clinical evaluation and cognitive assessment was completed in a Peruvian family with severe EOAD. Clinical course was characterized by very early onset (before age 35 years), progressive cognitive impairment with early memory loss, spatial disorientation and executive dysfunction. We sequenced all exons of PSEN1 in the proband and identified a c.475C>G DNA change resulting in a p.L153V missense mutation in the transmembrane domain 2 of the gene. This mutation is also present in the three additional affected siblings but not in a non-affected family member consistent with segregation of this mutation with the disease. This is the first report of a Peruvian family affected with EOAD associated with a PSEN1 mutation. This same mutation has been reported previously in English and French families, but a novel variants very close to the mutation and ancestry informative markers analysis suggests the mutation might be of Amerindian or African origin in this Peruvian family. PMID:24495933

  19. Curriculum Reform and the Displacement of Knowledge in Peruvian Rural Secondary Schools: Exploring the Unintended Local Consequences of Global Education Policies

    ERIC Educational Resources Information Center

    Balarin, Maria; Benavides, Martin

    2010-01-01

    This paper draws attention to processes of policy implementation in developing contexts, and to the unintended consequences of education policies that follow international policy scripts without enough consideration of local histories and cultures. Drawing on a study of teaching practices in Peruvian rural secondary schools after a period of…

  20. Leaf Wax δ13C Varies with Elevation in the Peruvian Andes and Western Amazonia

    NASA Astrophysics Data System (ADS)

    Wu, M. S.; Feakins, S. J.; Ponton, C.; Peters, T.; West, A. J.; Galy, V.; Bentley, L. P.; Salinas, N.; Shenkin, A.; Martin, R.; Asner, G. P.; Malhi, Y.

    2015-12-01

    Plant leaf wax carbon isotopic composition (δ13Cwax) reflects the net isotopic effects associated with diffusion into the leaf, fixation of carbon by Rubisco and biosynthesis of individual leaf wax biochemicals. As declining pCO2 with elevation affects the first two fractionations, we expect to find an isotopic gradient in δ13Cwax, if the fractionation of leaf wax biosynthesis is constant. To test this, we report δ13Cwax values from 500 samples of leaves collected by tree-climbers from the upper canopy from 9 forest-inventory plots spanning a 3.5km elevation transect in the Peruvian Andes and western Amazonia during the CHAMBASA field campaign. These samples provide a unique opportunity to study the relationship between δ13Cwax and pCO2 in diverse species across this remote tropical montane forest and lowland rainforest. The very wet climate throughout (2-5 m rainfall per year) minimizes fractionation effects due to stomatal restrictions (i.e. water use efficiency) that may be an important factor elsewhere. Preliminary results show δ13Cwax values on average increase with elevation by ~1.5‰/km, a trend consistent with bulk plant δ13C in previous studies. The mean epsilon between bulk and C29 n-alkane is -7.3±2.2‰. Inter-sample differences are large on the order of 10‰. Shaded leaves and understory leaves are found to be depleted relative to sunlit leaves, presumably due to a lower photosynthetic rate and use of respired CO2 in the understory. C29 n-alkanes are on average ~2.5‰ more depleted than C30 n-alkanoic acids, indicating fractionation during selective decarboxylation. We further compare results from plants with soil and river sediments to provide insights into how leaf wax signals are archived in soils and exported from the landscape. We find a ~1.4‰/km gradient in forest soils similar to plants. We observe a ~2‰ offset between C29 n-alkane in plant leaves and in soils across the elevation profile, which is likely a signal of degradation

  1. Field evaluation of a rapid diagnostic test (Parascreen™) for malaria diagnosis in the Peruvian Amazon

    PubMed Central

    2010-01-01

    Background The rapid diagnostic tests for malaria (RDT) constitute a fast and opportune alternative for non-complicated malaria diagnosis in areas where microscopy is not available. The objective of this study was to validate a RDT named Parascreen™ under field conditions in Iquitos, department of Loreto, Peru. Parascreen™ is a RDT that detects the histidine-rich protein 2 (HRP2) antigen from Plasmodium falciparum and lactate deshydrogenase from all Plasmodium species. Methods Parascreen™ was compared with microscopy performed by experts (EM) and polymerase chain reaction (PCR) using the following indicators: sensitivity (Se), specificity (Sp), positive (PV+) and negative predictive values (PV-), positive (LR+) and negative likehood ratio (LR-). Results 332 patients with suspected non-complicated malaria who attended to the MOH health centres were enrolled between October and December 2006. For P. falciparum malaria, Parascreen™ in comparison with EM, had Se: 53.5%, Sp: 98.7%, PV+: 66.7%, PV-: 97.8%, LR+: 42.27 and LR-: 0.47; and for non-P. falciparum malaria, Se: 77.1%, Sp: 97.6%, PV+: 91.4%, PV-: 92.7%, LR+: 32.0 and LR-: 0.22. The comparison of Parascreen™ with PCR showed, for P. falciparum malaria, Se: 81.8%, Sp: 99.1%, PV+: 75%, PV-: 99.4, LR+: 87.27 and LR-: 0.18; and for non-P. falciparum malaria Se: 76.1%, Sp: 99.2%, PV+: 97.1%, PV-: 92.0%, LR+: 92.51 and LR-: 0.24. Conclusions The study results indicate that Parascreen™ is not a valid and acceptable test for malaria diagnosis under the field conditions found in the Peruvian Amazon. The relative proportion of Plasmodium species, in addition to the genetic characteristics of the parasites in the area, must be considered before applying any RDT, especially after the finding of P. falciparum malaria parasites lacking pfhrp2 gene in this region. PMID:20529273

  2. Risk Factors Associated with Malnutrition in One-Year-Old Children Living in the Peruvian Amazon

    PubMed Central

    Joseph, Serene A.; Casapía, Martín; Blouin, Brittany; Maheu-Giroux, Mathieu; Rahme, Elham; Gyorkos, Theresa W.

    2014-01-01

    Background Children under two years of age are in the most critical window for growth and development. As mobility increases, this time period also coincides with first exposure to soil-transmitted helminth (STH) infections in tropical and sub-tropical environments. The association between malnutrition and STH infection, however, has been understudied in this vulnerable age group. Methodology/Principal Findings A nested cross-sectional survey was conducted in 12 and 13-month old children participating in a deworming trial in Iquitos, an STH-endemic area of the Peruvian Amazon. An extensive socio-demo-epi questionnaire was administered to the child's parent. Length and weight were measured, and the Bayley Scales of Infant and Toddler Development were administered to measure cognition, language, and fine motor development. Stool specimens were collected to determine the presence of STH. The association between malnutrition (i.e. stunting and underweight) and STH infection, and other child, maternal, and household characteristics, was analyzed using multivariable Poisson regression. A total of 1760 children were recruited between September 2011 and June 2012. Baseline data showed a prevalence of stunting and underweight of 24.2% and 8.6%, respectively. In a subgroup of 880 randomly-allocated children whose specimens were analyzed by the Kato-Katz method, the prevalence of any STH infection was 14.5%. Risk factors for stunting in these 880 children included infection with at least one STH species (aRR = 1.37; 95% CI 1.01, 1.86) and a lower development score (aRR = 0.97; 95% CI: 0.95, 0.99). A lower development score was also a significant risk factor for underweight (aRR = 0.92; 95% CI: 0.89, 0.95). Conclusions The high prevalence of malnutrition, particularly stunting, and its association with STH infection and lower developmental attainment in early preschool-age children is of concern. Emphasis should be placed on determining the most cost

  3. Is mercury from small-scale gold mining prevalent in the southeastern Peruvian Amazon?

    PubMed

    Moreno-Brush, Mónica; Rydberg, Johan; Gamboa, Nadia; Storch, Ilse; Biester, Harald

    2016-11-01

    There is an ongoing debate on the fate of mercury (Hg) in areas affected by artisanal and small-scale gold mining (ASGM). Over the last 30 years, ASGM has released 69 tons of Hg into the southeastern Peruvian Amazon. To investigate the role of suspended matter and hydrological factors on the fate of ASGM-Hg, we analysed riverbank sediments and suspended matter along the partially ASGM-affected Malinowski-Tambopata river system and examined Hg accumulation in fish. In addition, local impacts of atmospheric Hg emissions on aquatic systems were assessed by analysing a sediment core from an oxbow lake. Hg concentrations in riverbank sediments are lower (20-53 ng g(-1)) than in suspended matter (∼400-4000 ng g(-1)) due to differences in particle size. Elevated Hg concentrations in suspended matter from ASGM-affected river sections (∼1400 vs. ∼30-120 ng L(-1) in unaffected sections) are mainly driven by the increased amount of suspended matter rather than increased Hg concentrations in the suspended matter. The oxbow lake sediment record shows low Hg concentrations (64-86 ng g(-1)) without evidence of any ASGM-related increase in atmospheric Hg input. Hg flux variations are mostly an effect of variations in sediment accumulation rates. Moreover, only 5% of the analysed fish (only piscivores) exceed WHO recommendations for human consumption (500 ng g(-1)). Our findings show that ASGM-affected river sections in the Malinowski-Tambopata system do not exhibit increased Hg accumulation, indicating that the released Hg is either retained at the spill site or transported to areas farther away from the ASGM areas. We suspect that the fate of ASGM-Hg in such tropical rivers is mainly linked to transport associated with the suspended matter, especially during high water situations. We assume that our findings are typical for ASGM-affected areas in tropical regions and could explain why aquatic systems in such ASGM regions often show comparatively modest enrichment

  4. Medical ethnobotany of the Chayahuita of the Paranapura basin (Peruvian Amazon).

    PubMed

    Odonne, Guillaume; Valadeau, Céline; Alban-Castillo, Joaquina; Stien, Didier; Sauvain, Michel; Bourdy, Geneviève

    2013-03-07

    Up until now, the plant pharmacopoeia of the Chayahuita, an ethnic group from the Peruvian Amazon, has been poorly defined. This paper details the uses of medicinal plants within this community, as recorded in two villages of the Paranapura basin, Soledad and Atahualpa de Conchiyacu. This study aimed to describe the basis of the Chayahuita traditional medical system, to document part of the medicinal plant corpus, and to compare it with data from other Amazonian ethnic groups. Methodology was based (i) on field prospection with 26 informants (ethnobotanical walks methodology), (ii) semi-structured interviews including 93 people (49 men and 44 women) focused on the most recent health problem experienced and on the therapeutic options chosen, (iii) individual or group thematic discussions relating to disease and treatments, (iv) 6-months of participants' observations between May 2007 and May 2008. At the end of the project in May 2008 a workshop was organized to cross-check the data with the help of 12 of the most interested informants. Six hundred and seventeen voucher specimens were collected, corresponding to 303 different species, from which 274 (belonging to 83 families) are documented here. Altogether 492 recipes were recorded, corresponding to a global figure of 541 therapeutic uses and a total of 664 use reports. The main therapeutic uses are related to dermatological problems (103 uses; 19%), gastro-intestinal complaints (69 uses; 13%) and malaria/fevers (52 uses; 10%). Diseases are analysed according to Chayahuita concepts, and for each disease the species having a high frequency of citation are listed, and the most frequently used remedies are described. Whenever possible, comparisons with other Amazonian groups have been drawn. Chayahuita nosology and medical ethnobotany appear to draw their inspiration from a common panamazonian root. Despite the fact that a certain number of medicinal plants are shared with other nearby groups, there seem to be specific

  5. High Prevalence of Human T-Lymphotropic Virus Infection in Indigenous Women from the Peruvian Amazon

    PubMed Central

    García, Patricia J.; Cárcamo, Cesar; Montano, Silvia M.; Mori, Nicanor; Muñante, Ricardo; Zunt, Joseph R.

    2013-01-01

    Background In an earlier study, we detected an association between human T-cell lymphotropic virus (HTLV) infection and cervical human papillomavirus (HPV) in indigenous Amazonian Peruvian women of the Shipibo-Konibo ethnic group. As both HTLV and HPV can be transmitted sexually, we now report a population-based study examining the prevalence and risk factors for HTLV-1 and HTLV-2 infection in this population. Methods Between July and December 2010, we conducted a comprehensive screening for HTLV among Shipibo-Konibo women 15 to 39 years of age living in two communities located in Lima and in 17 communities located within four hours by car or boat from the Amazonian city of Pucallpa in Peru. Results We screened 1,253 Shipibo-Konibo women for HTLV infection 74 (5.9%) tested positive for HTLV-1, 47 (3.8%) for HTLV-2 infection, and 4 (0.3%) had indeterminate results. In the multivariate analysis, factors associated with HTLV-1 infection included: older age (Prevalence Ratio (PR): 1.04, 95% CI 1.00–1.08), primary education or less (PR: 2.01, 95% CI: 1.25–3.24), younger or same age most recent sex partner (PR: 1.66, 95% CI: 1.00–2.74), and having a most recent sex partner who worked at a logging camp (PR: 1.73, 95% CI: 1.09–2.75). The only factor associated with HTLV-2 infection was older age (PR: 1.08, 95% CI: 1.03–1.12). Conclusion HTLV infection is endemic among Shipibo-Konibo women. Two characteristics of the sexual partner (younger age and labor history) were associated with infection in women. These results suggest the need for implementation of both HTLV screening during the antenatal healthcare visits of Shipibo-Konibo women, and counseling about the risk of HTLV transmission through prolonged breastfeeding in infected women. We also recommend the implementation of prevention programs to reduce sexual transmission of these viruses. PMID:24040133

  6. Microbial Diversity in Maras Salterns, a Hypersaline Environment in the Peruvian Andes

    PubMed Central

    Maturrano, Lenin; Santos, Fernando; Rosselló-Mora, Ramon; Antón, Josefa

    2006-01-01

    Maras salterns are located 3,380 m above sea level in the Peruvian Andes. These salterns consist of more than 3,000 little ponds which are not interconnected and act as crystallizers where salt precipitates. These ponds are fed by hypersaline spring water rich in sodium and chloride. The microbiota inhabiting these salterns was examined by fluorescence in situ hybridization (FISH), 16S rRNA gene clone library analysis, and cultivation techniques. The total counts per milliliter in the ponds were around 2 × 106 to 3 × 106 cells/ml, while the spring water contained less than 100 cells/ml and did not yield any detectable FISH signal. The microbiota inhabiting the ponds was dominated (80 to 86% of the total counts) by Archaea, while Bacteria accounted for 10 to 13% of the 4′,6′-diamidino-2-phenylindole (DAPI) counts. A total of 239 16S rRNA gene clones were analyzed (132 Archaea clones and 107 Bacteria clones). According to the clone libraries, the archaeal assemblage was dominated by microorganisms related to the cosmopolitan square archaeon “Haloquadra walsbyi,” although a substantial number of the sequences in the libraries (31% of the 16S rRNA gene archaeal clones) were related to Halobacterium sp., which is not normally found in clone libraries from solar salterns. All the bacterial clones were closely related to each other and to the γ-proteobacterium “Pseudomonas halophila” DSM 3050. FISH analysis with a probe specific for this bacterial assemblage revealed that it accounted for 69 to 76% of the total bacterial counts detected with a Bacteria-specific probe. When pond water was used to inoculate solid media containing 25% total salts, both extremely halophilic Archaea and Bacteria were isolated. Archaeal isolates were not related to the isolates in clone libraries, although several bacterial isolates were very closely related to the “P. halophila” cluster found in the libraries. As observed for other hypersaline environments, extremely

  7. Hotspots of Malaria Transmission in the Peruvian Amazon: Rapid Assessment through a Parasitological and Serological Survey

    PubMed Central

    Rosas-Aguirre, Angel; Speybroeck, Niko; Llanos-Cuentas, Alejandro; Rosanas-Urgell, Anna; Carrasco-Escobar, Gabriel; Rodriguez, Hugo; Gamboa, Dionicia; Contreras-Mancilla, Juan; Alava, Freddy; Soares, Irene S.; Remarque, Edmond; D´Alessandro, Umberto; Erhart, Annette

    2015-01-01

    Background With low and markedly seasonal malaria transmission, increasingly sensitive tools for better stratifying the risk of infection and targeting control interventions are needed. A cross-sectional survey to characterize the current malaria transmission patterns, identify hotspots, and detect recent changes using parasitological and serological measures was conducted in three sites of the Peruvian Amazon. Material and Methods After full census of the study population, 651 participants were interviewed, clinically examined and had a blood sample taken for the detection of malaria parasites (microscopy and PCR) and antibodies against P. vivax (PvMSP119, PvAMA1) and P. falciparum (PfGLURP, PfAMA1) antigens by ELISA. Risk factors for malaria infection (positive PCR) and malaria exposure (seropositivity) were assessed by multivariate survey logistic regression models. Age-specific seroprevalence was analyzed using a reversible catalytic conversion model based on maximum likelihood for generating seroconversion rates (SCR, λ). SaTScan was used to detect spatial clusters of serology-positive individuals within each site. Results The overall parasite prevalence by PCR was low, i.e. 3.9% for P. vivax and 6.7% for P. falciparum, while the seroprevalence was substantially higher, 33.6% for P. vivax and 22.0% for P. falciparum, with major differences between study sites. Age and location (site) were significantly associated with P. vivax exposure; while location, age and outdoor occupation were associated with P. falciparum exposure. P. falciparum seroprevalence curves showed a stable transmission throughout time, while for P. vivax transmission was better described by a model with two SCRs. The spatial analysis identified well-defined clusters of P. falciparum seropositive individuals in two sites, while it detected only a very small cluster of P. vivax exposure. Conclusion The use of a single parasitological and serological malaria survey has proven to be an efficient

  8. Acoustic Properties Predict Perception of Unfamiliar Dutch Vowels by Adult Australian English and Peruvian Spanish Listeners

    PubMed Central

    Alispahic, Samra; Mulak, Karen E.; Escudero, Paola

    2017-01-01

    Research suggests that the size of the second language (L2) vowel inventory relative to the native (L1) inventory may affect the discrimination and acquisition of L2 vowels. Models of non-native and L2 vowel perception stipulate that naïve listeners' non-native and L2 perceptual patterns may be predicted by the relationship in vowel inventory size between the L1 and the L2. Specifically, having a smaller L1 vowel inventory than the L2 impedes L2 vowel perception, while having a larger one often facilitates it. However, the Second Language Linguistic Perception (L2LP) model specifies that it is the L1–L2 acoustic relationships that predict non-native and L2 vowel perception, regardless of L1 vowel inventory. To test the effects of vowel inventory size vs. acoustic properties on non-native vowel perception, we compared XAB discrimination and categorization of five Dutch vowel contrasts between monolinguals whose L1 contains more (Australian English) or fewer (Peruvian Spanish) vowels than Dutch. No effect of language background was found, suggesting that L1 inventory size alone did not account for performance. Instead, participants in both language groups were more accurate in discriminating contrasts that were predicted to be perceptually easy based on L1–L2 acoustic relationships, and were less accurate for contrasts likewise predicted to be difficult. Further, cross-language discriminant analyses predicted listeners' categorization patterns which in turn predicted listeners' discrimination difficulty. Our results show that listeners with larger vowel inventories appear to activate multiple native categories as reflected in lower accuracy scores for some Dutch vowels, while listeners with a smaller vowel inventory seem to have higher accuracy scores for those same vowels. In line with the L2LP model, these findings demonstrate that L1–L2 acoustic relationships better predict non-native and L2 perceptual performance and that inventory size alone is not a good

  9. The first report of Pb and Zn accumulation in some native plants from the Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Bech, Jaume; Duran, Paola; Poma, Wilfredo; Sánchez, Isidoro; Barceló, Juan; Roca, Núria; Boluda, Rafael; Roca-Pérez, Luís.; Poschenrieder, Charlotte

    2010-05-01

    Until recent decades little has been known about the remediation of mining sites using metalophytes in Latin America. Metal mining has helped to create severe and diverse environmental problems. The present study proposed to identify and characterize spontaneously growing heavy metal tolerant plant species in the area around the polimetalic mine in Hualgayoc (Cajamarca, Peru). These species are potentially useful for phytorremediation. Plant and soils from their rhizosphere were sampled and analized for concentration of As, Fe, Mn, Pb and Zn. Translocation Factor (TF) defined the metals concentrations ratio between shoots and root biomass and Shoot Accumulation Factor (SAF) the metal concentration ratio between shoot and soil concentration were determined and used to measure the effectiveness of a plant in concentrating metals into its biomass. The soils were neutral pH (7,4±0,5) with variable content of organic carbon (2,4±1,1) and loam texture: sand (42,9±10,8) and clay (16,7±4,6). According to the total metals, all samples exceeded toxicity thresholds, high Pb (20016 ± 32559 mg•kg-1) and Zn (22512 ± 13056 mg•kg-1) concentrations were detected. High shoot Pb and Zn concentrations were found in Plantaginaceae Plantago orbignyana (6998 and 9617 μg/g); Brassicaceae Lepidium bipinnatifidum (6886 and 5034 mg•kg-1) and Asteraceae Senecio sp (4253 and 3870 mg•kg-1) and Baccharis latifolia (2554 and 1284 mg•kg-1 respectively). The high values of TFs indicates that the plants effectively traslocated metales. Lepidium bipinnatifidum shows the highest TFs values (143 in Pb and 21,5 in Zn). The SAF values were much lower than those reported for other species such as Paspalum sp in the Peruvian copper mine, which may be due to a high top soil Pb and Zn concentrations. These species can surely be considered as interesting for phytoextraction, due not only to its accumulative capacity but also since they showed an elevated transfer factor and grew in the

  10. Improving Oil Palm Classification in the Peruvian Amazon by Combining Active and Passive Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Gutierrez-Velez, V. H.; DeFries, R. S.

    2011-12-01

    Oil palm expansion has led to clearing of extensive forest areas in the tropics. However quantitative assessments of the magnitude of oil palm expansion to deforestation have been challenging due in large part to the limitations presented by conventional optical data sets for discriminating plantations from forests and other tree cover vegetations. Recently available information from active remote sensors has opened the possibility of using these data sources to overcome these limitations. The purpose of this analysis is to evaluate the accuracy of oil palm classification when using ALOS/PALSAR active satellite data in conjunction with Landsat information, compared to the use of Landsat data only. The analysis takes place in a focused region around the city of Pucallpa in the Ucayali province of the Peruvian Amazon for the year 2010. Oil palm plantations were separated in five categories consisting of four age classes (0-3, 3-5, 5-10 and > 10 yrs) and an additional class accounting for degraded plantations older than 15 yr. Other land covers were water bodies, unvegetated land, short and tall grass, fallow, secondary vegetation, and forest. Classifications were performed using random forests. Training points for calibration and validation consisted of 411 polygons measured in areas representative of the land covers of interest and totaled 6,367 ha. Overall classification accuracy increased from 89.9% using only Landsat data sets to 94.3% using both Landast and ALOS/PALSAR. Both user's and producer's accuracy increased in all classes when using both data sets except for producer's accuracy in short grass which decreased by 1%. The largest increase in user's accuracy was obtained in oil palm plantations older than 10 years from 62 to 80% while producer's accuracy improved the most in plantations in age class 3-5 from 63 to 80%. Results demonstrate the suitability of data from ALOS/PALSAR and other active remote sensors to improve classification of oil palm

  11. Delivery by caesarean section and risk of childhood obesity: analysis of a Peruvian prospective cohort

    PubMed Central

    Miranda, J. Jaime; Bernabé-Ortiz, Antonio

    2015-01-01

    Objectives. We aimed to assess if Caesarean section is a risk factor for overnutrition in early- and late-childhood, and to assess the magnitude of the effect of child- versus family-related variables in these risk estimates. Methods. Longitudinal data from Peruvian children from the Young Lives Study was used. Outcomes assessed were overweight, obesity, overnutrition (overweight plus obesity), and central obesity (waist circumference) at the age 5 (first follow-up) and 7 (second follow-up) years. The exposure of interests was delivery by Caesarean section. Relative risks (RR) and 95% confidence intervals (95% CI) were calculated using multivariable models adjusted for child-related (e.g., birth weight) and family-related (e.g., maternal nutritional status) variables. Results. At baseline, mean age was 11.7 (± 3.5) months and 50.1% were boys. Children born by Caesarean section were 15.6%. The 10.5% of the children were overweight and 2.4% were obese. For the obesity outcome, data from 6,038 and 9,625 children-years was included from baseline to the first and second follow-up, respectively. Compared to those who did not experience Caesarean delivery, the risk of having obesity was higher in the group born by Caesarean: RRs were higher at early-childhood (first follow-up: 2.25; 95% CI [1.36–3.74]) than later in life (second follow-up: 1.57; 95% CI [1.02–2.41]). Family-related variables had a greater effect in attenuating the risk estimates for obesity at the first, than at the second follow-up. Conclusion. Our results suggest a higher probability of developing obesity, but not overweight, among children born by Caesarean section delivery. The magnitude of risk estimates decreased over time, and family-related variables had a stronger effect on the risk estimates at early-childhood. PMID:26137427

  12. Patterns of commercial fish landings in the Loreto region (Peruvian Amazon) between 1984 and 2006.

    PubMed

    Garcia, Aurea; Tello, Salvador; Vargas, Gladis; Duponchelle, Fabrice

    2009-03-01

    Patterns of commercial fish catches over the period from 1984 to 2006 were studied in the Loreto region and in Iquitos, which is the most important town of the region and the principal fish marketplace of the Peruvian Amazon. Despite important inter-annual variations, the overall fish landings have significantly increased in the region during this period. The same three species dominated the catches during the whole period (Prochilodus nigricans, Potamorhina altamazonica and Psectrogaster amazonica), making up about 62% of the catches. However, the number of species exploited by commercial fisheries increased considerably during the 22 years of this study (from about 21 species in 1984 to over 65 in 2006), although part of the difference may be accounted for by a better identification of individual species nowadays. At the same time, the large high-valued species, such as Arapaima gigas, Colossoma macropomum and Brachyplatystoma rousseauxii, declined significantly and were replaced by smaller, short-lived and lower-valued species. Catches of the silver Arahuana (Osteoglossum bicirrhosum) also declined significantly during the studied period, strengthening recent warnings about the species' conservation status (Moreau and Coomes, Oryx 40:152-160, 2006). The relative proportions of the trophic groups (detritivores, omnivores and piscivores) remained relatively constant over the study period, but there were significant changes in the relative abundances of the species groups. The proportion of the dominant group, the Characiformes, which averaged about 81% of the catches, increased between 1984 and 2006, whereas the proportion of the Siluriformes and Perciformes remained constant. On the other hand, the proportion of Osteoglossiformes, represented only by two well known species (Arapaima gigas and Osteoglossum bicirrhosum), declined sharply during the same period. Important differences were observed between the landings of Iquitos and the landing of the whole Loreto

  13. Aerobic capacity of Peruvian Quechua: a test of the developmental adaptation hypothesis.

    PubMed

    Kiyamu, Melisa; Rivera-Chira, María; Brutsaert, Tom D

    2015-03-01

    High altitude natives are reported to have outstanding work capacity in spite of the challenge of oxygen transport and delivery in hypoxia. To evaluate the developmental effect of lifelong exposure to hypoxia on aerobic capacity, VO2peak was measured on two groups of Peruvian Quechua subjects (18-35 years), who differed in their developmental exposure to altitude. Male and female volunteers were recruited in Lima, Peru (150 m), and were divided in two groups, based on their developmental exposure to hypoxia, those: a) Born at sea-level individuals (BSL), with no developmental exposure to hypoxia (n = 34) and b) Born at high-altitude individuals (BHA) with full developmental exposure to hypoxia (n = 32), but who migrated to sea-level as adults (>16-years-old). Tests were conducted both in normoxia (BP = 750 mm Hg) and normobaric hypoxia at sea-level (BP = 750 mm Hg, FiO2  = 0.12, equivalent to 4,449 m), after a 2-month training period (in order to control for initial differences in physical fitness) at sea-level. BHA had a significantly higher VO2peak at hypoxia (40.31 ± 1.0 ml/min/kg) as compared to BSL (35.78 ± 0.96 ml/min/kg, P = 0.001), adjusting for sex. The decrease of VO2peak at HA relative to SL (ΔVO2peak ) was not different between groups, controlling for baseline levels (VO2peak at sea-level) and sex (BHA = 0.35 ± 0.04 l/min, BSL = 0.44 ± 0.04 l/min; P = 0.12). Forced vital capacity (controlling for height) and the residuals of VO2peak (controlling for weight) had a significant association in the BHA group only (r = 0.155; P = 0.031). In sum, results indicate that developmental exposure to altitude constitutes an important factor to determine superior exercise performance. © 2014 Wiley Periodicals, Inc.

  14. Precipitation Indices as a Tool for Climate-Resilient Development in the Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Chisolm, R. E.; McKinney, D. C.

    2016-12-01

    The local people living in the mountains of the Ancash Department in Peru have noticed changes in their water supply as climate change has altered precipitation patterns. They are seeking adaptation solutions to help guarantee the reliability of their water supply, but there has been very little analysis of historical data to evaluate and justify these adaptation solutions. In addition, Peru's Ministry of Economy and Finance now requires that climate change be part of the vulnerability assessment for all public investment project proposals, but there are currently no tools or methods of data analysis for including climate change in vulnerability assessments. Compounding the difficulties of considering climate change in the sustainability of development projects is the scarcity of climate data in the region and the difficulty of accessing existing data. To counteract this problem, the Peruvian government recommends using local people's perceptions of change as a proxy for gauged climate data. This work focuses on precipitation data analysis in the mountains of Ancash, Peru. The objectives of this analysis were to determine the accuracy of the local population's perceptions of climate change and to investigate how changes in precipitation patterns might impact public investment projects. The precipitation data analysis was compared to a local study of perceptions of change to determine whether or not these perceptions might be used in lieu of gauged climate data. It appears that people's perceptions of precipitation trends do not accurately reflect the trends observed in the gauged data. The methods of analysis were designed so that the results may be useful for public investment projects with a particular emphasis on agricultural projects. The data were analyzed for trends, seasonal patterns and variability. Dry spells were examined, and the results indicate that droughts during the rainy season have become more frequent and of longer duration. This could have

  15. Correlates of early pregnancy serum brain-derived neurotrophic factor in a Peruvian population.

    PubMed

    Yang, Na; Levey, Elizabeth; Gelaye, Bizu; Zhong, Qiu-Yue; Rondon, Marta B; Sanchez, Sixto E; Williams, Michelle A

    2017-07-27

    Knowledge about factors that influence serum brain-derived neurotrophic factor (BDNF) concentrations during early pregnancy is lacking. The aim of the study is to examine the correlates of early pregnancy serum BDNF concentrations. A total of 982 women attending prenatal care clinics in Lima, Peru, were recruited in early pregnancy. Pearson's correlation coefficient was calculated to evaluate the relation between BDNF concentrations and continuous covariates. Analysis of variance and generalized linear models were used to compare the unadjusted and adjusted BDNF concentrations according to categorical variables. Multivariable linear regression models were applied to determine the factors that influence early pregnancy serum BDNF concentrations. In bivariate analysis, early pregnancy serum BDNF concentrations were positively associated with maternal age (r = 0.16, P < 0.001) and early pregnancy body mass index (BMI) (r = 0.17, P < 0.001), but inversely correlated with gestational age at sample collection (r = -0.21, P < 0.001) and C-reactive protein (CRP) concentrations (r = -0.07, P < 0.05). In the multivariable linear regression model, maternal age (β = 0.11, P = 0.001), early pregnancy BMI (β = 1.58, P < 0.001), gestational age at blood collection (β = -0.33, P < 0.001), and serum CRP concentrations (β = -0.57, P = 0.002) were significantly associated with early pregnancy serum BDNF concentrations. Participants with moderate antepartum depressive symptoms (Patient Health Questionnaire-9 (PHQ-9) score ≥ 10) had lower serum BDNF concentrations compared with participants with no/mild antepartum depressive symptoms (PHQ-9 score < 10). Maternal age, early pregnancy BMI, gestational age, and the presence of moderate antepartum depressive symptoms were statistically significantly associated with early pregnancy serum BDNF concentrations in low-income Peruvian women. Biological changes of CRP during pregnancy may affect serum

  16. Prevalence and correlates of human herpesvirus 8 infection among Peruvian men who have sex with men.

    PubMed

    Guanira, Juan V; Casper, Corey; Lama, Javier R; Morrow, Rhoda; Montano, Silvia M; Caballero, Patricia; Suárez, Luis; Whittington, William L H; Wald, Anna; Sanchez, Jorge; Celum, Connie

    2008-12-15

    Infection with human herpesvirus 8 (HHV-8) is common among men who have sex with men (MSM) in North America and Europe and is also found to be endemic in some regions of South America. Little is known about HHV-8 prevalence and its correlates among MSM in the Andean region. We assessed HHV-8 seroprevalence among 497 MSM recruited for the 2002 Peruvian HIV sentinel surveillance program using a combined HHV-8 enzyme immunoassay and immunofluorescence assay algorithm. Logistic regression analysis was used to estimate odds ratios (ORs) and their 95% confidence intervals (CIs) to determine the association between selected covariates and HHV-8 seropositivity. One hundred thirty-one (66.5%, 95% CI 63.1% to 69.9%) of 197 HIV-infected and 80 (26.7%, 95% CI 24.4% to 29.0%) of 300 HIV-uninfected MSM had serologic evidence of HHV-8 infection. Factors independently associated with HHV-8 infection were education<12 years (OR 1.7, 95% CI 1.1 to 2.7), anal receptive sex with the last partner (OR 2.0, 95% CI 1.2 to 3.3), self-reported sexually transmitted infection symptoms during the last year (OR 1.9, 95% CI 1.2 to 3.0), coinfection with HIV (OR 4.2, 95% CI 2.8 to 6.4) and chronic hepatitis B (OR 4.9, 95% CI 1.5 to 15.8). MSM with long-standing HIV infection were more likely to have serologic evidence of HHV-8 infection when compared with men with recently acquired HIV (OR 3.8, 95% CI 1.7 to 9.1). HHV-8 infection is common among both HIV-infected and HIV-negative MSM in Lima, Peru. HHV-8 seropositivity is correlated with anal receptive sex, self-reported sexually transmitted infection symptoms, and HIV infection among these MSM and thus seems to be sexually transmitted. HHV-8 infection seems to be acquired after HIV infection, suggesting that future studies should evaluate the mode of HHV-8 transmission and prevention strategies among HIV-uninfected MSM.

  17. High prevalence of human T-lymphotropic virus infection in indigenous women from the peruvian Amazon.

    PubMed

    Blas, Magaly M; Alva, Isaac E; García, Patricia J; Cárcamo, Cesar; Montano, Silvia M; Mori, Nicanor; Muñante, Ricardo; Zunt, Joseph R

    2013-01-01

    In an earlier study, we detected an association between human T-cell lymphotropic virus (HTLV) infection and cervical human papillomavirus (HPV) in indigenous Amazonian Peruvian women of the Shipibo-Konibo ethnic group. As both HTLV and HPV can be transmitted sexually, we now report a population-based study examining the prevalence and risk factors for HTLV-1 and HTLV-2 infection in this population. Between July and December 2010, we conducted a comprehensive screening for HTLV among Shipibo-Konibo women 15 to 39 years of age living in two communities located in Lima and in 17 communities located within four hours by car or boat from the Amazonian city of Pucallpa in Peru. We screened 1,253 Shipibo-Konibo women for HTLV infection 74 (5.9%) tested positive for HTLV-1, 47 (3.8%) for HTLV-2 infection, and 4 (0.3%) had indeterminate results. In the multivariate analysis, factors associated with HTLV-1 infection included: older age (Prevalence Ratio (PR): 1.04, 95% CI 1.00-1.08), primary education or less (PR: 2.01, 95% CI: 1.25-3.24), younger or same age most recent sex partner (PR: 1.66, 95% CI: 1.00-2.74), and having a most recent sex partner who worked at a logging camp (PR: 1.73, 95% CI: 1.09-2.75). The only factor associated with HTLV-2 infection was older age (PR: 1.08, 95% CI: 1.03-1.12). HTLV infection is endemic among Shipibo-Konibo women. Two characteristics of the sexual partner (younger age and labor history) were associated with infection in women. These results suggest the need for implementation of both HTLV screening during the antenatal healthcare visits of Shipibo-Konibo women, and counseling about the risk of HTLV transmission through prolonged breastfeeding in infected women. We also recommend the implementation of prevention programs to reduce sexual transmission of these viruses.

  18. Hearing impairment and poverty: the epidemiology of ear disease in Peruvian schoolchildren.

    PubMed

    Czechowicz, Josephine A; Messner, Anna H; Alarcon-Matutti, Edith; Alarcon, Jorge; Quinones-Calderon, Gina; Montano, Silvia; Zunt, Joseph R

    2010-02-01

    1) To measure prevalence of hearing impairment (HI) in schoolchildren living in poverty in Peru. 2) To identify risk factors for HI and assess its impact on academic performance. Cross-sectional. Elementary schools in an asentimiento humano (shantytown) near Lima, Peru, October 2008 to March 2009. Schoolchildren (n = 335), ages six to 19 years. Audiological health was assessed with pure-tone audiometry, tympanometry, and otoscopy. The primary outcome was HI, defined as average threshold >25 dB HL for 0.5, 1, 2, and 4 kHz, in one or both ears (per World Health Organization/International Organization for Standardization). A questionnaire on health history was administered to parents. Statistical analysis included univariate analysis for chi(2) values and odds ratios (ORs), and multivariate logistic regression. HI prevalence: 6.9 percent (95% confidence interval [CI] 4.2%-9.6%). Risk factors for HI (OR, 95% CI, P value): neonatal jaundice (5.59, 1.63-19.2, 0.015), seizure (7.31, 2.50-21.4, 0.0013), hospitalization (4.01, 1.66-9.68, 0.003), recurrent otitis media (5.06, 1.98-12.9, 0.002), past otorrhea (4.70, 1.84-12.0, 0.003), family history of HI at <35 years (2.91, 1.19-7.14, 0.026), tympanic membrane abnormality (13.8, 4.48-42.7, <0.001), cerumen impaction (15.8, 4.71-53.1, <0.001), and eustachian tube dysfunction (4.87, 1.74-13.7, <0.001). HI was an independent predictor of academic failure (3.36, 1.15-9.82, 0.03). Impoverished Peruvian schoolchildren were four to seven times more likely to experience HI than children living in higher-income countries. Untreated middle ear disease in the context of limited access to pediatric care was a major risk factor for HI. Furthermore, HI was associated with worse scholastic achievement. These results support prioritization of pediatric ear health as an essential component of the global health agenda, especially in resource-poor countries. Copyright 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation

  19. Cold episodes in the Peruvian Central Andes: Composites, Types, and their Impacts over South America (1958-2014)

    NASA Astrophysics Data System (ADS)

    Sulca, J. C.; Vuille, M. F.; Roundy, P. E.; Trasmonte, G.; Silva, Y.; Takahashi, K.

    2015-12-01

    The Mantaro basin (MB) is located in the central Peruvian Andes. Occasionally, cold episodes are observed during austral summer (January-March), that strongly damage crops. However, little is known about the causes and impacts of such cold episodes. The main goal of this study is thus to characterize cold episodes in the MB and assess their large-scale circulation and teleconnections over South America (SA) during austral summer. To identify cold events in the MB daily minimum temperature (Tmin) for the period 1958-2014 from Huayao station, located within the MB was used. A cold episode is defined when daily minimum temperature drops below its 10-percentile for at least one day. Additionally, to study the sensitivity between physical mechanisms associated with cold episodes and temperature, cold episodes are classified in three groups: Weak cold episodes (7.5 ≤ Tmin ≤ 10 percentile), strong cold episodes (Tmin ≤ 2.5 percentile), but excluding the 9 coldest events (Tmin ≤ 0 ͦ C), henceforth referred to as extraordinary cold episodes. Several gridded reanalysis were used to characterize the large-scale circulation, cloud cover and rainfall over SA associated with these events. Weak and strong cold episodes in the MB are mainly associated with a weakening of the Bolivian High-Nordeste Low system by tropical-extratropical interactions. Both types of cold episodes are associated with westerly wind anomalies at mid- and upper-tropospheric levels aloft the Peruvian Central Andes, which inhibit the influx of humid air masses from the lowlands to the east and hence limit the development of cloud cover (e.g., positive OLR anomalies over MB). The resulting clear sky conditions cause nighttime temperatures to drop, leading to cold extremes below 10-percentile. Simultaneously, northeastern Brazil (NEB) registers negative OLR anomalies, strong convection and enhanced cloud cover because displacement of the South Atlantic Convergence Zone (SACZ) toward the northeast of

  20. Neotropics provide insights into the emergence of New World monkeys: New dental evidence from the late Oligocene of Peruvian Amazonia.

    PubMed

    Marivaux, Laurent; Adnet, Sylvain; Altamirano-Sierra, Ali J; Boivin, Myriam; Pujos, François; Ramdarshan, Anusha; Salas-Gismondi, Rodolfo; Tejada-Lara, Julia V; Antoine, Pierre-Olivier

    2016-08-01

    Recent field efforts in Peruvian Amazonia (Contamana area, Loreto Department) have resulted in the discovery of a late Oligocene (ca. 26.5 Ma; Chambira Formation) fossil primate-bearing locality (CTA-61). In this paper, we analyze the primate material consisting of two isolated upper molars, the peculiar morphology of which allows us to describe a new medium-sized platyrrhine monkey: Canaanimico amazonensis gen. et sp. nov. In addition to the recent discovery of Perupithecus ucayaliensis, a primitive anthropoid taxon of African affinities from the alleged latest Eocene Santa Rosa locality (Peruvian Amazonia), the discovery of Canaanimico adds to the evidence that primates were well-established in the Amazonian Basin during the Paleogene. Our phylogenetic results based on dental evidence show that none of the early Miocene Patagonian taxa (Homunculus, Carlocebus, Soriacebus, Mazzonicebus, Dolichocebus, Tremacebus, and Chilecebus), the late Oligocene Bolivian Branisella, or the Peruvian Canaanimico, is nested within a crown platyrrhine clade. All these early taxa are closely related and considered here as stem Platyrrhini. Canaanimico is nested within the Patagonian Soriacebinae, and closely related to Soriacebus, thereby extending back the soriacebine lineage to 26.5 Ma. Given the limited dental evidence, it is difficult to assess if Canaanimico was engaged in a form of pitheciine-like seed predation as is observed in Soriacebus and Mazzonicebus, but dental microwear patterns recorded on one upper molar indicate that Canaanimico was possibly a fruit and hard-object eater. If Panamacebus, a recently discovered stem cebine from the early Miocene of Panama, indicates that the crown platyrrhine radiation was already well underway by the earliest Miocene, Canaanimico indicates in turn that the "homunculid" radiation (as a part of the stem radiation) was well underway by the late Oligocene. These new data suggest that the stem radiation likely occurred in the Neotropics

  1. Exploratory application of the Ages and Stages (ASQ) child development screening test in a low-income Peruvian shantytown population

    PubMed Central

    Kyerematen, Victoria; Hamb, Averine; Oberhelman, Richard A; Cabrera, Lilia; Bernabe-Ortiz, Antonio; Berry, Susan J

    2014-01-01

    Objectives Public health research on child health is increasingly focusing on the long-term impacts of infectious diseases, malnutrition and social deprivation on child development. The objectives of this exploratory study were to (1) implement the Ages and Stages Questionnaires (ASQ) in children aged 3 months to 5 years in a low-income Peruvian population and (2) to correlate outcomes of the ASQ with risk factors such as nutritional status, diarrhoea incidence and wealth index. Setting Primary data collection was carried out in the Pampas de San Juan de Miraflores, a periurban low-income community in Lima, Peru. Participants The study population included 129 children selected through community census data, with a mean age of 22 months (SD 6.8) and with almost equal gender distribution (51% males). Intervention A Peruvian psychologist administered the age-appropriate (ASQ2 for participants enrolled in 2009, ASQ3 for participants enrolled in 2010). Results of the ASQ are reported separately for five scales, including Communication, Gross Motor, Fine Motor, Problem Solving and Personal-Social. Primary and secondary outcome measures For each scale, results are reported as normal or suspect, meaning that some milestone attainment was not evident and further evaluation is recommended. Results Overall, 50 of 129 children (38.7%) had suspect results for at least one of the five scales, with the highest rates of suspect results on the Communication (15.5%) and Problem Solving scales (13.9%). Higher rates of suspect outcomes were seen in older children, both overall (p=0.06) and on Problem Solving (p=0.009), and for some scales there were trends between suspect outcomes and wealth index or undernutrition. Conclusions The ASQ was successfully applied in a community-based study in a low-income Peruvian population, and with further validation, the ASQ may be an effective tool for identifying at-risk children in resource-poor areas of Latin America. PMID:24413354

  2. Epidemiological investigation of an acute case of Chagas disease in an area of active transmission in Peruvian Amazon region.

    PubMed

    Cabrera, Rufino; Vega, Silvia; Cáceres, Abraham G; Ramal, A César; Alvarez, Carlos; Ladera, Pedro; Pinedo, Raul; Chuquipiondo, Gladys

    2010-01-01

    The study objective was to investigate an acute case of Chagas disease in the San Pedro de Shishita community, Pebas District, in the Peruvian Amazon basin, a non-endemic area. Both parents of the index case (acute case) were thoroughly interviewed, a seroepidemiological survey was carried out in the community, parasitological exams were carried out only in relatives of the index case, and triatomine bugs were searched for inside houses, peridomiciliary, and in wild environments. Seroprevalence for IgG anti-T. cruzi antibodies was 1/104 (0.96%), using an ELISA test and an indirect immunofluorescence assay. Panstrongylus geniculatus and Rhodnius pictipes adults were found. The index case is autochthonous from San Pedro de Shishita, but the source of transmission is unknown.

  3. Llaki and ñakary: idioms of distress and suffering among the highland Quechua in the Peruvian Andes.

    PubMed

    Pedersen, Duncan; Kienzler, Hanna; Gamarra, Jeffrey

    2010-06-01

    This article examines some of the long-term health outcomes of extreme adversities and the ways in which social inequalities and idioms of distress are historically and socially produced in the Peruvian context. We describe how the highland Quechua of northern Ayacucho construct and experience expressions of distress and suffering such as pinsamientuwan (worrying thoughts, worries), ñakary (suffering) and llaki (sorrow, sadness), in a context of persistent social inequalities, social exclusion and a recent history of political violence. It is concluded that the multiple expressions of distress and suffering are closely related to past and current events, shaped by beliefs, core values and cultural norms and, in this process, transformed, recreated and invested with new meanings and attributions.

  4. A large and unusually colored new snake species of the genus Tantilla (Squamata; Colubridae) from the Peruvian Andes

    PubMed Central

    Venegas, Pablo J.

    2016-01-01

    A new colubrid species of the genus Tantilla from the dry forest of the northern Peruvian Andes is described on the basis of two specimens, which exhibit a conspicuous sexual dimorphism. Tantilla tjiasmantoi sp. nov. represents the third species of the genus in Peru. The new species is easily distinguished from its congeners by the combination of scalation characteristics and the unusual transversely-banded color pattern on the dorsum. A detailed description of the skull morphology of the new species is given based on micro-computed tomography images. The habitat of this new species is gravely threatened due to human interventions. Conservation efforts are urgently needed in the inter-Andean valley of the Maranon River. PMID:27994975

  5. [Letters to the editor published in Peruvian biomedical journals indexed in SciELO-Peru 2006-2013].

    PubMed

    Montenegro-Idrogo, Juan José; Mejía-Dolores, Jhon William; Chalco-Huamán, Joel L

    2015-01-01

    This bibliometric study describes the characteristics of letters to the editor published between 2006-2013 in biomedical journals indexed in SciELO-Peru.253 letters (10.3% of total publications) were collected. Most letters (139) were in the Peruvian Journal of Experimental Medicine and Public Health, with marked increase throughout those years. 25% of letters submitted included medical student participation. 14% of authors presented with international affiliations and 27% with endogenous affiliation - common in university journals (Anales de la Facultad de Medicina, Revista Médica Herediana).The usual criteria justifying the publication of letters were: opinion of medical fact or public domain (35.6%) and discussion of results, methodological flaws or interpretation (22.9%). In biomedical journals indexed in SciELO Peru the letters to the editor comprise a percentage of publications that has increased in recent years, with low publication of letters of findings or primary data, compared with opinion or criticism.

  6. Adherence to 7-Day Primaquine Treatment for the Radical Cure of P. vivax in the Peruvian Amazon

    PubMed Central

    Grietens, Koen Peeters; Soto, Veronica; Erhart, Annette; Ribera, Joan Muela; Toomer, Elizabeth; Tenorio, Alex; Montalvo, Tanilu Grande; Rodriguez, Hugo; Cuentas, Alejandro Llanos; D'Alessandro, Umberto; Gamboa, Dionicia

    2010-01-01

    Despite being free of charge, treatment adherence to 7-day primaquine for the radical cure of Plasmodium vivax was estimated at 62.2% among patients along the Iquitos-Nauta road in the Peruvian Amazon. The principal reason for non-adherence was the perceived adverse effects related to local humoral illness conceptions that hold that malaria produces a hot state of body, which is further aggravated by the characteristically hot medical treatment. Notably, patients were willing to adhere to the first 3 days of treatment during which symptoms are most apparent and include the characteristic chills. Nevertheless, as symptoms abate, the perceived aggravating characteristics of the medication outweigh the perceived advantages of treatment adherence. Improving community awareness about the role of primaquine to prevent further malaria transmission and fostering a realistic system of direct observed treatment intake, organized at community level, can be expected to improve adherence to the radical cure of P. vivax in this area. PMID:20519594

  7. Insights from the genome of a high alkaline cellulase producing Aspergillus fumigatus strain obtained from Peruvian Amazon rainforest.

    PubMed

    Paul, Sujay; Zhang, Angel; Ludeña, Yvette; Villena, Gretty K; Yu, Fengan; Sherman, David H; Gutiérrez-Correa, Marcel

    2017-06-10

    Here, we report the complete genome sequence of a high alkaline cellulase producing Aspergillus fumigatus strain LMB-35Aa isolated from soil of Peruvian Amazon rainforest. The genome is ∼27.5mb in size, comprises of 228 scaffolds with an average GC content of 50%, and is predicted to contain a total of 8660 protein-coding genes. Of which, 6156 are with known function; it codes for 607 putative CAZymes families potentially involved in carbohydrate metabolism. Several important cellulose degrading genes, such as endoglucanase A, endoglucanase B, endoglucanase D and beta-glucosidase, are also identified. The genome of A. fumigatus strain LMB-35Aa represents the first whole sequenced genome of non-clinical, high cellulase producing A. fumigatus strain isolated from forest soil. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Different selection pressures give rise to distinct ethnic phenomena : a functionalist framework with illustrations from the Peruvian Altiplano.

    PubMed

    Moya, Cristina; Boyd, Robert

    2015-03-01

    Many accounts of ethnic phenomena imply that processes such as stereotyping, essentialism, ethnocentrism, and intergroup hostility stem from a unitary adaptation for reasoning about groups. This is partly justified by the phenomena's co-occurrence in correlational studies. Here we argue that these behaviors are better modeled as functionally independent adaptations that arose in response to different selection pressures throughout human evolution. As such, different mechanisms may be triggered by different group boundaries within a single society. We illustrate this functionalist framework using ethnographic work from the Quechua-Aymara language boundary in the Peruvian Altiplano. We show that different group boundaries motivate different ethnic phenomena. For example, people have strong stereotypes about socioeconomic categories, which are not cooperative units, whereas they hold fewer stereotypes about communities, which are the primary focus of cooperative activity. We also show that, despite the cross-cultural importance of ethnolinguistic boundaries, the Quechua-Aymara linguistic distinction does not strongly motivate any of these intergroup processes.

  9. The tragedy of Tauccamarca: a human rights perspective on the pesticide poisoning deaths of 4 children in the Peruvian Andes.

    PubMed

    Rosenthal, Erika

    2003-01-01

    The pesticide poisoning deaths of 24 children in an isolated Peruvian village make a compelling case that corporate accountability for pesticide poisonings in the developing south should be examined from a human rights perspective. Highly toxic pesticides cannot be used safely under prevailing socioeconomic conditions. The industry asserts that the deaths of these children were accidental, blaming misuse. Tragedies such as these poisonings are not accidents, but foreseeable, and therefore preventable. Sales of highly toxic pesticides that cause repeated and predictable poisonings violate the fundamental human rights to life, health, and security of person. The Tauccamarca tragedy is a clear example of the urgency of applying a precautionary, human rights approach to pesticide issues in the developing south.

  10. [Information technologies intended to solve contingencies in the Peruvian subsidized health system affiliation: "Resuelve tu afiliación"].

    PubMed

    Villegas-Ortega, José; Loyola-Martínez, César; Santisteban-Romero, Javier; Manchego-Lombardi, Mónica; Lozada-Urbano, Michelle

    2016-01-01

    The National Health Authority (SUSALUD) has developed an online platform, "ReSUelve tu afiliación", with the intent to solve the problems with health service access experienced by Peruvian citizens who hold health insurance policies through institutions that manage health insurance funds (IAFAS). This platform virtually articulates the main IAFAS in Peru, which receives requests from any user requiring an update on his/her affiliation status to be resolved within 24 hours. Nearly 8 months after the implementation of this platform, more than 55 thousand applications have been resolved, thus ensuring timely access to health services under the corresponding user coverage form. As a result, this platform has helped to guarantee citizens' rights to health service access in the face of infringement caused by delays in affiliation processing among the different IAFAS in Peru.

  11. A new gluco indole alkaloid, 3, 4-dehydro-5-carboxystrictosidine, from Peruvian Uña de Gato (Uncaria tomentosa).

    PubMed

    Kitajima, M; Hashimoto, K; Yokoya, M; Takayama, H; Aimi, N; Sakai, S I

    2000-10-01

    A new gluco indole alkaloid, 3,4-dehydro-5-carboxystrictosidine, was obtained from Peruvian Uña de Gato (Cat's Claw, original plant: Uncaria tomentosa) together with two known gluco indole alkaloids. This compound was the first example of isolation of a gluco monoterpenoid indole alkaloid having a 3,4-dihydro-beta-carboline ring system from nature. A characteristic feature of the compound was the quick replacement of the methylene hydrogens on C-14 with deuterium that was observed when it was dissolved in CD3OD. We demonstrated a similar proton-deuterium exchange on a model compound, 1-methyl-3,4-dihydro-gamma-carboline, in CD3OD solution.

  12. A large and unusually colored new snake species of the genus Tantilla (Squamata; Colubridae) from the Peruvian Andes.

    PubMed

    Koch, Claudia; Venegas, Pablo J

    2016-01-01

    A new colubrid species of the genus Tantilla from the dry forest of the northern Peruvian Andes is described on the basis of two specimens, which exhibit a conspicuous sexual dimorphism. Tantilla tjiasmantoi sp. nov. represents the third species of the genus in Peru. The new species is easily distinguished from its congeners by the combination of scalation characteristics and the unusual transversely-banded color pattern on the dorsum. A detailed description of the skull morphology of the new species is given based on micro-computed tomography images. The habitat of this new species is gravely threatened due to human interventions. Conservation efforts are urgently needed in the inter-Andean valley of the Maranon River.

  13. Divergence in parental care, habitat selection and larval life history between two species of Peruvian poison frogs: an experimental analysis.

    PubMed

    Brown, J L; Morales, V; Summers, K

    2008-11-01

    Changes in the nature of the ecological resources exploited by a species can lead to the evolution of novel suites of behaviours. We identified a case in which the transition from large pool use to the use of very small breeding pools in neotropical poison frogs (family Dendrobatidae) is associated with the evolution of a suite of behaviours, including biparental care (from uniparental care) and social monogamy (from promiscuity). We manipulated breeding pool size in order to demonstrate experimentally that breeding habitat selection strategy has evolved in concert with changes in parental care and mating system. We also manipulated intra- and interspecific larval interactions to demonstrate that larval adaptation to the use of very small pools for breeding affected the evolution of larval competition and cannibalism. Our results illustrate the intimate connection between breeding pool ecology, parental care and mating strategies in Peruvian poison frogs.

  14. Recording Earthen Architecture at the Peruvian Andes: the Case of KUÑO Tambo CHURCH'S Historic Wall Paintings

    NASA Astrophysics Data System (ADS)

    Percy, K.; Hanley, C.; Santana Quintero, M.; Fai, S.; Ouimet, C.; Cancino, C.; Rainer, L.; Villacorta-Santamato, L.

    2013-07-01

    According to UNESCO "Earthen architecture is one of the most original and powerful expressions of our ability to create a built environment with readily available resources. It includes a great variety of structures, ranging from mosques, palaces and granaries, to historic city centres, cultural landscapes and archaeological sites" (WHEAP, 2007). This contribution looks at developing effective methods for recording earthen historic structures for their rehabilitation and preservation using the Kuño Tambo church in Peru, which is a Peruvian national historic site that requires serious rehabilitation work, as a case study. This project describes the compilation of an effective metric record of the "state-of-conservation" - "as found" of wall paintings in this important and remote building using a toolbox of different "off-the-shelf" heritage recording techniques. This approach was applied by Carleton Immersive Media Studio (CIMS), as part of the Earthen Architecture Initiative of the Getty Conservation Institute (GCI).

  15. Sustaining a hygiene education intervention to prevent and control geohelminth infections at schools in the Peruvian Amazon.

    PubMed

    Thériault, François L; Blouin, Brittany; Casapía, Martín; Gyorkos, Theresa W

    2015-10-01

    The World Health Organization currently recommends that school-based deworming programs include health hygiene education as a complementary measure. However, the sustainability and long-term impact of such hygiene education had yet to be assessed. In July 2012, this cross-sectional study was conducted in 18 primary schools in the Peruvian Amazon to gauge continuing adherence to a health hygiene education intervention introduced 2 years earlier to reduce soil-transmitted helminth infections. Due in large part to high teacher turn-over, only 9 of 47 (19.1%) teachers were still implementing the intervention. Health hygiene education interventions must, therefore, be designed to ensure sustainability in order to contribute to the overall effectiveness of school-based deworming programs.

  16. Impacts of petroleum activities for the Achuar people of the Peruvian Amazon: summary of existing evidence and research gaps

    NASA Astrophysics Data System (ADS)

    Orta Martínez, Martí; Napolitano, Dora A.; MacLennan, Gregor J.; O'Callaghan, Cristina; Ciborowski, Sylvia; Fabregas, Xavier

    2007-10-01

    Petrol has been extracted from Achuar territory in the Northern Peruvian Amazon since the 1970s. In spite of early identification of negative impacts on the environment and repeated attempts by the Achuar to improve conditions, very little research has been done on specific environmental and health impacts. Some recent governmental studies have shown extremely high blood lead and cadmium levels in Achuar communities. In this paper we apply an environmental justice framework to review the evidence of pollution and health status available in existing studies, as well as government and operating company actions over the last 30 years. We identify gaps in our knowledge which hamper efforts to respond to the environmental and health situation, as well as negligent actions on the part of the State and petrol companies.

  17. [Molecular cloning and characterization in silico of phospholipase A(2) transcript isolated from Lachesis muta peruvian snake venom].

    PubMed

    Jimenez, Karim L; Zavaleta, Amparo I; Izaguirre, Victor; Yarleque, Armando; Inga, Rosio R

    2010-01-01

    Isolate and characterize in silico gene phospholipase A(2) (PLA(2)) isolated from Lachesis muta venom of the Peruvian Amazon. Technique RT-PCR from total RNA was using specific primers, the amplified DNA product was inserted into the pGEM vector for subsequent sequencing. By bioinformatic analysis identified an open reading frame of 414 nucleotides that encoded 138 amino acids including a signal peptide of 16 aminoacids, molecular weight and pI were 13,976 kDa and 5.66 respectively. The aminoacid sequence was called Lm-PLA(2)-Peru, contains an aspartate at position 49, this aminoacid in conjunction with other conserved residues such as Tyr-28, Gly-30, Gly-32, His-48, Tyr52, Asp99 are important for enzymatic activity. The comparison with the amino acid sequence data banks showed of similarity between PLA(2) from Lachesis stenophrys (93%) and other PLA(2) snake venoms and over 80% of other sPLA(2) family Viperidae venoms. A phylogenetic analysis showed that Lm-PLA(2)-Peru grouped with other acidic [Asp(49)] sPLA(2) previously isolated from Bothriechis schlegelii venom showing 89 % nucleotide sequence identity. Finally, the computer modeling indicated that enzyme had the characteristic structure of sPLA(2) group II that consisted of three α-helices, a β-wing, a short helix and a calcium-binding loop. The nucleotide sequence corresponding to the first transcript of gene from PLA(2) cloned of Lachesis muta venom, snake from the Peruvian rainforest.

  18. In vitro Antimicrobial Activity of Traditional Plant Used in Mestizo Shamanism from the Peruvian Amazon in Case of Infectious Diseases

    PubMed Central

    Roumy, Vincent; Gutierrez-Choquevilca, Andréa-Luz; Lopez Mesia, Jean Pierre; Ruiz, Lastenia; Ruiz Macedo, Juan Celidonio; Abedini, Amin; Landoulsi, Ameni; Samaillie, Jennifer; Hennebelle, Thierry; Rivière, Céline; Neut, Christel

    2015-01-01

    Context: Our survey was performed near Iquitos (Peruvian Amazon) and its surroundings and leads us to consider Mestizo ethnomedical practices. The plant species reported here are traditionally used for ailments related to microbial infections. Inhabitants of various ethnic origins were interviewed, and 52 selected plants extracts were evaluated for their antimicrobial properties against a panel of 36 sensitive and multi-resistant bacteria or yeast. The study aimed at providing information on antimicrobial plant extract activities and the ethnomedical context of Mestizo riverine populations from Loreto (Peru). Material and Method: The minimum inhibitory concentrations (MICs) of the plant crude extracts were carried out using the agar dilution method and ranged between 0.075 and 5.0 mg/ml. Results: Of the 40 plants analyzed, 9 species showed MIC ≤0.3 mg/ml (Anacardium occidentale, Couroupita guianensis, Croton lechleri, Davilla rugosa, Erythrina amazonica, Jacaranda copaia subsp. Spectabilis, Oenocarpus bataua, Peperomia macrostachya, and Phyllanthus urinaria) for one or several of the 36 microorganisms and only 6 drug extracts were inactive. Among the 40 plants, 13 were evaluated for the first time for an antibacterial activity. Conclusion: This evaluation of the antimicrobial activity of 40 plants using an approved standard methodology allowed comparing those activities against various microbes to establish antimicrobial spectra of standardized plant extracts, and give support to the traditional use of these plants. It may also help discovering new chemical classes of antimicrobial agents that could serve against multi-resistant bacteria. SUMMARY This study leads us to consider Mestizo ethnomedical practices near Iquitos (Peruvian Amazon) and its surroundings. The plant species reported here are traditionally used for ailments related to microbial infections. 52 selected plants extracts were evaluated for their antimicrobial properties against a panel of 36

  19. Rapid Diagnostic Tests for Malaria Diagnosis in the Peruvian Amazon: Impact of pfhrp2 Gene Deletions and Cross-Reactions

    PubMed Central

    Maltha, Jessica; Gamboa, Dionicia; Bendezu, Jorge; Sanchez, Luis; Cnops, Lieselotte; Gillet, Philippe; Jacobs, Jan

    2012-01-01

    Background In the Peruvian Amazon, Plasmodium falciparum and Plasmodium vivax malaria are endemic in rural areas, where microscopy is not available. Malaria rapid diagnostic tests (RDTs) provide quick and accurate diagnosis. However, pfhrp2 gene deletions may limit the use of histidine-rich protein-2 (PfHRP2) detecting RDTs. Further, cross-reactions of P. falciparum with P. vivax-specific test lines and vice versa may impair diagnostic specificity. Methods Thirteen RDT products were evaluated on 179 prospectively collected malaria positive samples. Species diagnosis was performed by microscopy and confirmed by PCR. Pfhrp2 gene deletions were assessed by PCR. Results Sensitivity for P. falciparum diagnosis was lower for PfHRP2 compared to P. falciparum-specific Plasmodium lactate dehydrogenase (Pf-pLDH)- detecting RDTs (71.6% vs. 98.7%, p<0.001). Most (19/21) false negative PfHRP2 results were associated with pfhrp2 gene deletions (25.7% of 74 P. falciparum samples). Diagnostic sensitivity for P. vivax (101 samples) was excellent, except for two products. In 10/12 P. vivax-detecting RDT products, cross-reactions with the PfHRP2 or Pf-pLDH line occurred at a median frequency of 2.5% (range 0%–10.9%) of P. vivax samples assessed. In two RDT products, two and one P. falciparum samples respectively cross-reacted with the Pv-pLDH line. Two Pf-pLDH/pan-pLDH-detecting RDTs showed excellent sensitivity with few (1.0%) cross-reactions but showed faint Pf-pLDH lines in 24.7% and 38.9% of P. falciparum samples. Conclusion PfHRP2-detecting RDTs are not suitable in the Peruvian Amazon due to pfhrp2 gene deletions. Two Pf-pLDH-detecting RDTs performed excellently and are promising RDTs for this region although faint test lines are of concern. PMID:22952633

  20. Modelling the potential of focal screening and treatment as elimination strategy for Plasmodium falciparum malaria in the Peruvian Amazon Region.

    PubMed

    Rosas-Aguirre, Angel; Erhart, Annette; Llanos-Cuentas, Alejandro; Branch, Oralee; Berkvens, Dirk; Abatih, Emmanuel; Lambert, Philippe; Frasso, Gianluca; Rodriguez, Hugo; Gamboa, Dionicia; Sihuincha, Moisés; Rosanas-Urgell, Anna; D'Alessandro, Umberto; Speybroeck, Niko

    2015-05-07

    Focal screening and treatment (FSAT) of malaria infections has recently been introduced in Peru to overcome the inherent limitations of passive case detection (PCD) and further decrease the malaria burden. Here, we used a relatively straightforward mathematical model to assess the potential of FSAT as elimination strategy for Plasmodium falciparum malaria in the Peruvian Amazon Region. A baseline model was developed to simulate a scenario with seasonal malaria transmission and the effect of PCD and treatment of symptomatic infections on the P. falciparum malaria transmission in a low endemic area of the Peruvian Amazon. The model was then adjusted to simulate intervention scenarios for predicting the long term additional impact of FSAT on P. falciparum malaria prevalence and incidence. Model parameterization was done using data from a cohort study in a rural Amazonian community as well as published transmission parameters from previous studies in similar areas. The effect of FSAT timing and frequency, using either microscopy or a supposed field PCR, was assessed on both predicted incidence and prevalence rates. The intervention model indicated that the addition of FSAT to PCD significantly reduced the predicted P. falciparum incidence and prevalence. The strongest reduction was observed when three consecutive FSAT were implemented at the beginning of the low transmission season, and if malaria diagnosis was done with PCR. Repeated interventions for consecutive years (10 years with microscopy or 5 years with PCR), would allow reaching near to zero incidence and prevalence rates. The addition of FSAT interventions to PCD may enable to reach P. falciparum elimination levels in low endemic areas of the Amazon Region, yet the progression rates to those levels may vary substantially according to the operational criteria used for the intervention.

  1. Quaternary marine terraces and maximum tectonic uplift rate of the Peruvian coast at 15. 5/sup 0/S latitude

    SciTech Connect

    Hsu, J.T.; Bloom, A.L.

    1985-01-01

    Numerous and well preserved marine terraces near San Juan de Marcona, Peru are a result of tectonic uplift related to subduction of the Nazca Plate, combined with Quaternary sea level fluctuations. A flight of 10 terraces from modern sea level up to 310 m has been sampled and surveyed along two transects. The lowest terrace surface is covered with cobble beach ridges and is truncated by a modern sea cliff 29 m above sea level. It may be the continuation of an abrasion platform with a well developed shoreline angle at 41 m. The extreme aridity of the Peruvian coastal desert is responsible for the preservation and lack of alteration of the terrace deposits. All landforms and sedimentary facies of the modern surf zone are still recognizable on the terraces. Abundant and well preserved mollusk shells, all of which are nearshore or surf zone species, can be found on most of the terraces. Uncorrected radiocarbon ages of pelecypods in growth position on the lowest terrace were >40,000 year B.P. If this lowest terrace is older than 40,000 yr. B.P. then its next most likely time of formation was during the 62,000 year B.P. interstadial event. By this hypothesis, a wide and well developed terrace at 148 m would have been formed during the 125,000 year B.P. interglacial high sea level, and the average uplift rate would have been 1.2 m/1000 year. This uplift rate is the maximum that can be assumed for this section of the Peruvian coast, because if the terraces are even older, the uplift rate must have been less.

  2. Depletion of oxygen, nitrate and nitrite in the Peruvian oxygen minimum zone cause an imbalance of benthic nitrogen fluxes

    NASA Astrophysics Data System (ADS)

    Sommer, S.; Gier, J.; Treude, T.; Lomnitz, U.; Dengler, M.; Cardich, J.; Dale, A. W.

    2016-06-01

    Oxygen minimum zones (OMZ) are key regions for fixed nitrogen loss in both the sediments and the water column. During this study, the benthic contribution to N cycling was investigated at ten sites along a depth transect (74-989 m) across the Peruvian OMZ at 12°S. O2 levels were below detection limit down to ~500 m. Benthic fluxes of N2, NO3-, NO2-, NH4+, H2S and O2 were measured using benthic landers. Flux measurements on the shelf were made under extreme geochemical conditions consisting of a lack of O2, NO3- and NO2- in the bottom water and elevated seafloor sulphide release. These particular conditions were associated with a large imbalance in the benthic nitrogen cycle. The sediments on the shelf were densely covered by filamentous sulphur bacteria Thioploca, and were identified as major recycling sites for DIN releasing high amounts of NH4+up to 21.2 mmol m-2 d-1 that were far in excess of NH4+ release by ammonification. This difference was attributed to dissimilatory nitrate (or nitrite) reduction to ammonium (DNRA) that was partly being sustained by NO3- stored within the sulphur oxidizing bacteria. Sediments within the core of the OMZ (ca. 200-400 m) also displayed an excess flux of N of 3.5 mmol m-2 d-1 mainly as N2. Benthic nitrogen and sulphur cycling in the Peruvian OMZ appears to be particularly susceptible to bottom water fluctuations in O2, NO3- and NO2-, and may accelerate the onset of pelagic euxinia when NO3- and NO2- become depleted.

  3. Novel and known MYOC exon 3 mutations in an admixed Peruvian primary open-angle glaucoma population

    PubMed Central

    Mendoza-Reinoso, Veronica; Guevara-Fujita, Maria L.; Fernández, Silvia; Vargas, Enrique; Castillo-Herrera, Wilder; Perez-Grossmann, Rodolfo; Lizaraso-Caparó, Frank; Richards, Julia E.; Fujita, Ricardo

    2012-01-01

    Purpose The aim of this study was to characterize a representative sample of the Peruvian population suffering open-angle glaucoma (OAG) with respect to the myocilin gene (MYOC) mutations, glaucoma phenotype, and ancestry for future glaucoma risk assessment. Methods DNA samples from 414 unrelated Peruvian subjects, including 205 open-angle glaucoma cases (10 juvenile glaucoma [JOAG], 19 normal-tension glaucoma [NTG], and 176 POAG) and 209 randomly sampled controls, were screened for nucleotide changes in MYOC exon 3 by conformational sensitive gel electrophoresis (CSGE) and mutation screening. Results We identified a probable causative novel MYOC missense mutation, Gly326Ser, in one POAG case and found a consistent genotype-phenotype correlation in eight of his relatives. We also found the known causative MYOC mutation Trp286Arg in one JOAG case and one POAG case. A known causative single base MYOC deletion, T1357, was found in one POAG case. Two previously reported silent polymorphisms, Thr325Thr and Tyr347Tyr, were found in both the case and the control populations. A novel missense variant, Met476Arg, was identified in two unrelated controls. Conclusions The screening of exon 3 of MYOC in a representative sample of 205 independent POAG patients from Peru and 209 matched controls identified novel and previously reported mutations (both pathogenic and nonpathogenic) from other global regions. These results reflect the complex admixture of Amerindian and Old World ancestry in urban populations of Latin America, in general, and in Peru, in particular. It will be important to gather information about the ancestral origin of MYOC and other POAG gene mutations to develop screening panels and risk assessment for POAG in Peru. PMID:22879734

  4. Outbreak of 2009 pandemic influenza A (H1N1) on a Peruvian Navy ship - June-July 2009.

    PubMed

    2010-02-19

    On June 25, 2009, a naval cadet reported to the infirmary of a 355-crewman Peruvian Navy ship with a febrile acute respiratory infection (FARI) 5 days after the ship docked in San Francisco, California. Pandemic 2009 influenza A (H1N1) virus was suspected as the cause because it was circulating in the city at that time. A test for pandemic H1N1 by real-time reverse transcription--polymerase chain reaction (rRT-PCR) was positive. During the subsequent 3 weeks, as the ship continued its cruise, 77 additional crew members developed confirmed pandemic H1N1 influenza. The U.S. Naval Medical Research Center Detachment (NMRCD), in collaboration with the Peruvian Navy, conducted an investigation to describe the outbreak and determine the attack rate for pandemic H1N1 influenza on the ship. This report summarizes the results of that investigation, which indicated that, of the 85 patients with FARI, 78 (92%) tested positive for pandemic H1N1 by rRT-PCR. The attack rate for confirmed pandemic H1N1 influenza was 22.0%. The most frequent symptoms, other than fever, were cough, headache, nasal congestion, and malaise. No complications or deaths occurred. Patients were treated according to World Health Organization (WHO) influenza treatment guidelines; six patients received antiviral medication because of preexisting comorbidities. A shipboard respiratory surveillance program, which had been implemented aboard the ship before its departure from Peru, permitted the early detection of the outbreak. Subsequent implementation of control measures might have slowed the outbreak. Laboratory disease surveillance and adequate outbreak control procedures might reduce transmission of pandemic H1N1 influenza aboard ships.

  5. Validation of a susceptibility, benefits, and barrier scale for mammography screening among Peruvian women: a cross-sectional study

    PubMed Central

    2011-01-01

    Background Perceived beliefs about breast cancer and breast cancer screening are important predictors for mammography utilization. This study adapted and validated the Champion's scale in Peru. This scale measures perceived susceptibility for breast cancer and perceived benefits and barriers for mammography. Methods A cross-sectional study was conducted among women ages 40 to 65 attending outpatient gynecology services in a public hospital in Peru. A group of experts developed and pre-tested a Spanish version of the Champion's scale to assess its comprehensibility (N = 20). Factor analysis, internal consistency, and test-retest reliability analyses were performed (N = 285). Concurrent validity compared scores from participants who had a mammogram and those who did not have it in the previous 15 months. T-test and multiple regression analysis adjusting for socio-demographic factors, mammography knowledge and other preventive behaviors were performed. Results The construct validity and reliability were optimal. Cronbach-Alpha coefficients were 0.75 (susceptibility), 0.72 (benefits) and 0.86 (barriers). Concurrent validity analysis showed an association between barriers and mammography screening use in bivariate (22.3 ± 6.7 vs. 30.2 ± 7.6; p < 0.001) and multiple regression analysis (OR = 0.28, 95% CI = 0.18-0.43). Ages 50-60 years (OR = 2.35, 95% CI = 1.19-4.65), history of prior Papanicolaou test (OR = 3.69, 95% CI = 1.84-7.40), and knowledge about breast cancer and mammography (OR = 3.69, 95% CI = 1.84-7.40) were also independently associated with mammography screening use. Conclusion Concurrent validity analysis showed that the Champion's scale has important limitations for assessing perceived susceptibility for breast cancer and perceived benefits for mammography among Peruvian women. There is still a need for developing valid and reliable instruments for measuring perceived beliefs about breast cancer and mammography screening among Peruvian women. PMID

  6. Evidence of Teleconnections between the Peruvian central Andes and Northeast Brazil during extreme rainfall events

    NASA Astrophysics Data System (ADS)

    Sulca, J. C.; Vuille, M. F.; Silva, F. Y.; Takahashi, K.

    2013-12-01

    Knowledge about changes in regional circulation and physical processes associated with extreme rainfall events in South America is limited. Here we investigate such events over the Mantaro basin (MB) located at (10°S-13°S; 73°W-76°W) in the central Peruvian Andes and Northeastern Brazil (NEB), located at (9°S-15°S; 39°W-46°W). Occasional dry and wet spells can be observed in both areas during the austral summer season. The main goal of this study is to investigate potential teleconnections between extreme rainfall events in MB and NEB during austral summer. We define wet (dry) spells as periods that last for at least 3 (5) consecutive days with rainfall above (below) the 70 (30) percentile. To identify the dates of ocurrence of these events, we used daily accumulated rainfall data from 14 climate stations located in the Mantaro basin for the period 1965 to 2002. In NEB we defined a rainfall index which is based on average daily gridded rainfall data within the region for the same period. Dry (wet spells) in the MB are associated with positive (negative) OLR anomalies which extend over much of the tropical Andes, indicating the large-scale nature of these events. At 200 hPa anomalous easterly (westerly) zonal winds aloft accompany wet (dry) spells. Composite anomalies of dry spells in MB reveal significant contemporaneous precipitation anomalies of the opposite sign over NEB, which suggest that intraseasonal precipitation variability over the two regions may be dynamically linked. Indeed upper-tropospheric circulation anomalies over the central Andes extend across South America and appear to be tied to an adjustment in the Bolivian High-Nordeste Low system. Dry (wet) spells in NEB are equally associated with a large-scale pattern of positive (negative) OLR anomalies; however, there are no related significant OLR anomalies over the MB during these events. Dry (wet) spells are associated with robust patterns of anomalous wind fields at both low and upper

  7. Effects of different land-uses on soil organic carbon pools in the Peruvian tropical forests

    NASA Astrophysics Data System (ADS)

    Oliver, V.; Kala, J.; Lever, R.; Teh, Y.

    2013-12-01

    Tropical soils are a large carbon reservoir, acting as both a source and a sink of CO2. Changes to these soil environments have major implications for long term carbon storage and rising atmospheric CO2 concentrations. Enhanced CO2 emissions originate, in large part, from the decomposition and loss of soil organic matter (SOM) following anthropogenic disturbances such as deforestation or agricultural conversion. Therefore, quantitative knowledge of the stabilisation and decomposition of SOM is necessary in order to understand, assess and predict the impact of land use change in the tropics. In particular, labile SOM is an early and sensitive indicator of how SOM responds to changes in land use and management practices. The main focus of this study is to explore the relationship between soil respiration, decomposition and soil C pools in order to estimate the turnover times of soil C on a suite of different land uses in the Peruvian tropical forests. Three major C pools (light fractions, occluded light fractions and heavy fractions) were separated using sodium polytungstate in a density fraction technique, soil CO2 flux was measured bimonthly over a year using a closed-chamber technique and decomposition rates were estimated using buried birch wood sticks acting as a common substrate across the sites. Our results showed that CO2 flux ranged from 0.237-7.676 μmol m-2s-1 for the banana plantation, 2.773-11.1 μmol m-2s-1 for the mature forest, 1.718-17.005 μmol m-2s-1 for pasture and 2.931-5.216 μmol m-2s-1 for the secondary forest. On an annual basis, the soil CO2 flux was highest in the pasture ecosystem with an estimated production of 2.3 kg C m-2yr-1 followed by the banana plantation with 1.3 kg C m-2yr-1 and the mature forest site with 1.0 kg C m-2yr-1. Land use affected soil temperature and bulk density, which also showed positive correlations with CO2 flux. The stick decomposition rate was significantly faster on the pasture site in comparison to the forest

  8. Microbial methanogenesis in the sulfate-reducing zone of surface sediments traversing the Peruvian margin

    NASA Astrophysics Data System (ADS)

    Maltby, J.; Sommer, S.; Dale, A. W.; Treude, T.

    2015-09-01

    We studied the concurrence of methanogenesis and sulfate reduction in surface sediments (0-25 cm below sea floor, cmbsf) at six stations (70, 145, 253, 407, 770 and 1024 m) along the Peruvian margin (12° S). This oceanographic region is characterized by high carbon export to the seafloor, creating an extensive oxygen minimum zone (OMZ) on the shelf, both factors that could favor surface methanogenesis. Sediments sampled along the depth transect traversed areas of anoxic and oxic conditions in the bottom-near water. Net methane production (batch incubations) and sulfate reduction (35S-sulfate radiotracer incubation) were determined in the upper 0-25 cmbsf of multicorer cores from all stations, while deep hydrogenotrophic methanogenesis (> 30 cmbsf, 14C-bicarbonate radiotracer incubation) was determined in two gravity cores at selected sites (78 and 407 m). Furthermore, stimulation (methanol addition) and inhibition (molybdate addition) experiments were carried out to investigate the relationship between sulfate reduction and methanogenesis. Highest rates of methanogenesis and sulfate reduction in the surface sediments, integrated over 0-25 cmbsf, were observed on the shelf (70-253 m, 0.06-0.1 and 0.5-4.7 mmol m-2 d-1, respectively), while lowest rates were discovered at the deepest site (1024 m, 0.03 and 0.2 mmol m-2 d-1, respectively). The addition of methanol resulted in significantly higher surface methanogenesis activity, suggesting that the process was mostly based on non-competitive substrates, i.e., substrates not used by sulfate reducers. In the deeper sediment horizons, where competition was probably relieved due to the decline of sulfate, the usage of competitive substrates was confirmed by the detection of hydrogenotrophic activity in the sulfate-depleted zone at the shallow shelf station (70 m). Surface methanogenesis appeared to be correlated to the availability of labile organic matter (C / N ratio) and organic carbon degradation (DIC production

  9. Microbial methanogenesis in the sulfate-reducing zone of surface sediments traversing the Peruvian margin

    NASA Astrophysics Data System (ADS)

    Maltby, J.; Sommer, S.; Dale, A. W.; Treude, T.

    2016-01-01

    We studied the concurrence of methanogenesis and sulfate reduction in surface sediments (0-25 cm below sea floor) at six stations (70, 145, 253, 407, 990 and 1024 m) along the Peruvian margin (12° S). This oceanographic region is characterized by high carbon export to the seafloor creating an extensive oxygen minimum zone (OMZ) on the shelf, both factors that could favor surface methanogenesis. Sediments sampled along the depth transect traversed areas of anoxic and oxic conditions in the bottom-near water. Net methane production (batch incubations) and sulfate reduction (35S-sulfate radiotracer incubation) were determined in the upper 0-25 cm b.s.f. of multiple cores from all stations, while deep hydrogenotrophic methanogenesis (> 30 cm b.s.f., 14C-bicarbonate radiotracer incubation) was determined in two gravity cores at selected sites (78 and 407 m). Furthermore, stimulation (methanol addition) and inhibition (molybdate addition) experiments were carried out to investigate the relationship between sulfate reduction and methanogenesis.

    Highest rates of methanogenesis and sulfate reduction in the surface sediments, integrated over 0-25 cm b.s.f., were observed on the shelf (70-253 m, 0.06-0.1 and 0.5-4.7 mmol m-2 d-1, respectively), while lowest rates were discovered at the deepest site (1024 m, 0.03 and 0.2 mmol m-2 d-1, respectively). The addition of methanol resulted in significantly higher surface methanogenesis activity, suggesting that the process was mostly based on non-competitive substrates - i.e., substrates not used by sulfate reducers. In the deeper sediment horizons, where competition was probably relieved due to the decrease of sulfate, the usage of competitive substrates was confirmed by the detection of hydrogenotrophic activity in the sulfate-depleted zone at the shallow shelf station (70 m).

    Surface methanogenesis appeared to be correlated to the availability of labile organic matter (C / N ratio) and organic carbon

  10. Morphology of the oxyurid nematodes Trypanoxyuris (T.) cacajao n. sp. and T. (T.) ucayalii n. sp. from the red uakari monkey Cacajao calvus ucayalii in the Peruvian Amazon.

    PubMed

    Conga, D F; Giese, E G; Serra-Freire, N M; Bowler, M; Mayor, P

    2016-07-01

    Cacajao calvus ucayalii (Thomas, 1928) (Primates: Pitheciidae), a subspecies endemic to the Peruvian Amazon, occurs in patchy and sometimes isolated populations in north-eastern Peru and is in a vulnerable situation, mainly due to habitat loss and hunting. This rareness and remote distribution means that, until now, parasitical studies have been limited. Based on optical and scanning electron microscopy of specimens of both sexes, we report two new species of Trypanoxyuris pinworms occurring in the large intestine of the Peruvian red uakari, namely Trypanoxyuris (Trypanoxyuris) cacajao and Trypanoxyuris (Trypanoxyuris) ucayalii. Both species showed a distinct morphology of the lips and cephalic structure. Sexual dimorphism in the lateral alae was observed in both male and the female worms, with ventral ornamentation being shown in the oesophageal teeth. The finding of these new pinworm species highlights the possibility of discovering other species.

  11. Active tectonics of Peru: Heterogeneous interseismic coupling along the Nazca megathrust, rigid motion of the Peruvian Sliver, and Subandean shortening accommodation

    NASA Astrophysics Data System (ADS)

    Villegas-Lanza, J. C.; Chlieh, M.; Cavalié, O.; Tavera, H.; Baby, P.; Chire-Chira, J.; Nocquet, J.-M.

    2016-10-01

    Over 100 GPS sites measured in 2008-2013 in Peru provide new insights into the present-day crustal deformation of the 2200 km long Peruvian margin. This margin is squeezed between the eastward subduction of the oceanic Nazca Plate at the South America trench axis and the westward continental subduction of the South American Plate beneath the Eastern Cordillera and Subandean orogenic wedge. Continental active faults and GPS data reveal the rigid motion of a Peruvian Forearc Sliver that extends from the oceanic trench axis to the Western-Eastern Cordilleras boundary and moves southeastward at 4-5 mm/yr relative to a stable South America reference frame. GPS data indicate that the Subandean shortening increases southward by 2 to 4 mm/yr. In a Peruvian Sliver reference frame, the residual GPS data indicate that the interseismic coupling along the Nazca megathrust is highly heterogeneous. Coupling in northern Peru is shallow and coincides with the site of previous moderate-sized and shallow tsunami-earthquakes. Deep coupling occurs in central and southern Peru, where repeated large and great megathrust earthquakes have occurred. The strong correlation between highly coupled areas and large ruptures suggests that seismic asperities are persistent features of the megathrust. Creeping segments appear at the extremities of great ruptures and where oceanic fracture zones and ridges enter the subduction zone, suggesting that these subducting structures play a major role in the seismic segmentation of the Peruvian margin. In central Peru, we estimate a recurrence time of 305 ± 40 years to reproduce the great 1746 Mw 8.8 Lima-Callao earthquake.

  12. Psychological Operations Changes that the Peruvian Army Should Implement During Counterinsurgency Operations Against the Informational Campaigns of Sendero Luminoso Political Branch Since 2000

    DTIC Science & Technology

    2017-06-09

    to have the chance to learn from them. They patiently taught me and fully supported my efforts with their time, interest, and extensive knowledge. I...Schleifer concluded first, that democracies should learn PSYOPS techniques, adapt them and use them against their opponents, and aid themselves in...Concha wrote an investigation with the purpose to analyze the counterinsurgency doctrinal changes that the Peruvian Army learned from the SL insurgency

  13. The seed of abundance and misery Peruvian living standards from the early republican period to the end of the guano era (1820-1880).

    PubMed

    Twrdek, Linda; Manzel, Kerstin

    2010-07-01

    This paper examines 19th-century Peruvian heights from the early republican period to the end of the guano era (1820-1880). Analyzing male and female prisoner heights from the Lima penitentiary, we find that the physical stature of the lower classes stagnated throughout the period. In spite of the substantial profits generated by Peru's chief export product, guano, these revenues apparently did not filter down to benefit ordinary laborers.

  14. Evidence for Asymmetrical Divergence-Gene Flow of Nuclear Loci, but Not Mitochondrial Loci, between Seabird Sister Species: Blue-Footed (Sula nebouxii) and Peruvian (S. variegata) Boobies

    PubMed Central

    Taylor, Scott A.; Anderson, David J.; Friesen, Vicki L.

    2013-01-01

    Understanding the process of speciation requires understanding how gene flow influences divergence. Recent analyses indicate that divergence can take place despite gene flow and that the sex chromosomes can exhibit different levels of gene flow than autosomes and mitochondrial DNA. Using an eight marker dataset including autosomal, z-linked, and mitochondrial loci we tested the hypothesis that blue-footed (Sula nebouxii) and Peruvian (S. variegata) boobies diverged from their common ancestor with gene flow, paying specific attention to the differences in gene flow estimates from nuclear and mitochondrial markers. We found no gene flow at mitochondrial markers, but found evidence from the combined autosomal and z-linked dataset that blue-footed and Peruvian boobies experienced asymmetrical gene flow during or after their initial divergence, predominantly from Peruvian boobies into blue-footed boobies. This gene exchange may have occurred either sporadically between periods of allopatry, or regularly throughout the divergence process. Our results add to growing evidence that diverging species can remain distinct but exchange genes. PMID:23614045

  15. High-resolution Terrestrial Laser Scanning (TLS) on cushion peatlands - a case study from the Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Forbriger, M.; Höfle, B.; Siart, C.; Schittek, K.; Bubenzer, O.

    2012-04-01

    So-called cushion peatlands located in the high mountain areas of the Peruvian Andes are unique ecotopes, which are of major importance for both palaeoenvironmental reconstructions and permanent water supply of the valley oases in the presently hyperarid Peruvian desert. In this context, a case study was performed on the Cerro Llamoca peatland (southern Peru, province Lucanas, 14° S) in the uppermost reaches of the Rió Grande catchment area (4000-4450 m a.s.l.) within the framework of the BMBF-funded project 'Andean Transect - Climate Sensitivity of pre-Columbian Man-Environment-Systems' and serves as a basis for a long-term, multitemporal observation study. As small-scale geomorphologic investigations require high-resolution elevation data, which is still not available for this remote study site, and local microrelief is characterised by features not visible from aerial view (e.g. channel cuttings within the peatland), terrestrial laser scanning (TLS) was applied. Data acquisition was carried out with one of the latest 'time-of-flight'-scanners (Riegl VZ-400). A total of 46 positions was recorded to capture the whole area of interest leading to more 370 million single laser points within an area of approximately 1,8 km2. Registration of scan positions was performed by means of GPS measurements, coarse registration and the iterative closest point (ICP) algorithm provided by the plugin Multi-Station Adjustment within the RiSCAN PRO software (Riegl). The large amount of output data required the use of special LiDAR software for further processing and digital elevation raster generation (OPALS software). The defined target raster resolution was set to values between 0.1 and 2 m depending on the average point density. It is important to have access to the original point cloud including additional laser point attributes (e.g. signal amplitude and echo width) for digital terrain model generation (i.e. terrain point filtering) and geomorphologic mapping by means of

  16. Cosmogenic 10Be Dating of Early and Latest Holocene Moraines on Nevado Salcantay in the Southern Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Licciardi, J. M.; Schaefer, J. M.; Lund, D. C.

    2007-12-01

    A two-fold sequence of nested lateral and end moraines was mapped in a glacial trough emanating from the southwest flank of Nevado Salcantay (6271 m; ~13°S latitude), the highest peak in the Cordillera Vilcabamba of southern Peru. The field area is situated 25 km due south of the archaeological site of Machu Picchu. Outer and inner moraines in the sequence were deposited by valley glaciers that terminated ~5 km and ~3 km, respectively, from their headwall on the Salcantay summit massif. Cosmogenic 10Be surface exposure dating of granitic boulders sampled on the Salcantay moraines is underway and has provided the first numerical ages for these deposits. Initial results indicate ages of 8.1 ± 0.1 10Be ka for the outer moraine and 200 ± 20 10Be years for the sharp-crested inner moraine. These ages are derived using the CRONUS-Earth 10Be exposure age calculator (version 2.0) and expressed with respect to the Lal- Stone production rate scaling scheme using the standard atmosphere. The outer and inner moraine ages correspond to glacial events during the early and latest Holocene, respectively. Further 10Be dating of the mapped moraines and similar deposits observed in adjacent drainages on Nevado Salcantay is anticipated to yield a high-resolution chronology of valley glaciation in this segment of the southern Peruvian Andes. The new results bridge an important gap between existing Andean glacier records to the north and south, and complement available ice core and lacustrine paleoclimate records in the vicinity, thereby expanding spatial and temporal coverage for identifying patterns of Holocene climate change in the tropical Andes. Notably, the inner moraine age correlates with the timing of the Little Ice Age as defined in northern mid- and high latitude glacier records, and suggests considerable expansion of valley glaciers in the southern Peruvian Andes during this climatic minimum. Apart from their paleoclimatic significance, the initial results also demonstrate

  17. Cooling and Exhumation of the Coastal Batholith in the Peruvian Andes (5-12°S)

    NASA Astrophysics Data System (ADS)

    Michalak, M.; Hall, S. R.; Farber, D.; Hourigan, J. K.; Audin, L.

    2014-12-01

    The South American Andes exhibit strong morphological differences along strike, shaped by a combination of tectonic forces and surface processes. In the central Peruvian Andes (~12°S) a major morphological transition occurs; to the north, the spines of the Western and Eastern Cordilleras come together into a relatively narrow configuration of high topography. In Southern Peru, the region of high topography widens, where the Western and Eastern Cordilleras flank the broad, Altiplano plateau. Despite this morphological change, the Mesozoic-early Cenozoic Coastal Batholith outcrops continuously from 0°-18°S along the western margin of the Peruvian Andes, emplaced along a trench-parallel marginal basin in the Mesozoic. The Coastal Batholith is an ideal geologic setting to investigate potential differences in rock exhumation and cooling histories along the western margin of Peru. While the cooling history of the southern Coastal Batholith has been previously used to estimate timing and magnitude of rock exhumation in Southern Peru, north of 12°S it is poorly constrained. We present 16 zircon and 7 apatite (U-Th)/He mean-ages from three sites, across seven degrees of latitude (5°S to 12°S). In general, ZHe and AHe ages capture two stages of cooling, Oligocene-to-mid-Miocene and mid-to-late Miocene, respectively. We model time-temperature histories of samples with paired AHe and ZHe ages using a Monte-Carlo inversion of HeFTy® (Ketcham, 2005); best fit time-temperature pathways show cooling rates ranging from ~2-24°C/my, where fastest cooling rates are generally observed in the mid-Miocene. To estimate exhumation rates, we apply a simple thermal model to account for nonuniform geothermal gradients expected in a trench-arc setting. Exhumation rates range from ~0.2mm/yr in the north, to 0.4-0.7mm/yr in the south, and rates increase orogenward, where mean elevation is highest. These results, particularly the predominance of Miocene ZHe and AHe data, and the younging

  18. Venezuelan equine encephalitis and Oropouche virus infections among Peruvian army troops in the Amazon region of Peru.

    PubMed

    Watts, D M; Lavera, V; Callahan, J; Rossi, C; Oberste, M S; Roehrig, J T; Cropp, C B; Karabatsos, N; Smith, J F; Gubler, D J; Wooster, M T; Nelson, W M; Hayes, C G

    1997-06-01

    An outbreak of a febrile illness characterized by headache, ocular pain, myalgia, and arthralgia occurred during June 1994 among Peruvian army troops in Northern Peru. On June 14-16, 1994, clinical data and blood samples were obtained from eight soldiers with a febrile illness, and from 26 others who had a history of febrile illness during the past three months. A follow-up blood sample was obtained 107 days later from four of the febrile and seven of the afebrile soldiers. Serum samples were tested for dengue (DEN), Oropouche (ORO), and Venezuelan equine encephalitis (VEE) IgM and IgG antibodies by an enzyme-linked immunosorbent assay (ELISA). Virus isolation was performed by inoculation of newborn mice and Vero cell cultures. Viral isolates were identified by immunofluorescence, ELISA, and nucleotide sequencing. A VEE virus infection was confirmed in three of the eight febrile soldiers, two by virus isolation, and one by serology. Antigenic analysis indicated that one of the virus isolates was similar to VEE subtype I, variety ID, viruses previously isolated in Colombia and Venezuela. Nucleotide sequence data showed that both viral isolates were identical to one another and closely related to VEE ID viruses previously isolated in Peru, Colombia, and Venezuela. Serologic results showed that two of 26 afebrile soldiers had IgM antibody to VEE and four had IgG antibody to VEE; two febrile soldiers had IgG antibody in their first serum samples. Oropouche-specific IgM antibody was detected in one of the eight febrile and five of the afebrile soldiers, and 18 of the 34 soldiers had low titers of ORO IgG antibody titers, which did not meet the diagnostic criteria for confirmed cases. All soldiers were negative for DEN IgM antibody, and 10 had flavivirus IgG antibody that reacted with DEN antigens. These data indicated that VEE ID virus was one of the causes of illness among Peruvians soldiers and that this was the first association of this VEE subtype with human disease

  19. Cenozoic crustal shortening and thickening contributions to Andean orogenesis: Preliminary results from structural mapping in the southern Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Perez, N.; Horton, B. K.

    2012-12-01

    Estimates of Cenozoic crustal shortening and thickening from the southern Peruvian Andes are necessary to address ongoing debates regarding growth of the Andes and Altiplano plateau. However, limited regional studies in southern Peru prevent accurate assessments of the structural contributions to high topography. This study provides new structural mapping along a >200 km transect spanning the northernmost Altiplano to Subandes at 13-15.5°S and fills the gap between existing central Peruvian and northern Bolivian studies. New stratigraphic data, fault relationships and fold orientations are used to create an updated geologic map and provide insights into the style, timing and magnitude of crustal deformation. Preliminary cross sections accompanying these map transects illustrate deformation style and provide first-order estimates of shortening. Further cross section analyses will be balanced and provide estimates of total crustal shortening and associated thickening in southern Peru. The study transect is subdivided into belts according to the age of exposed rocks and style of deformation. From west to east these belts include: Cretaceous strata dominated by tight folds, closely spaced faults and multiple detachments; Permo-Triassic strata dominated by thicker thrust sheets and fault-fold orientations departing from typical Andean trends; and Paleozoic rocks characterized by thick thrust sheets and deformation focused near major faults. The Cretaceous belt is composed of marine limestones and upward coarsening, siltstone to coarse sandstone progradational sequences. Disharmonic and detachment folds in the Cretaceous section demonstrate the importance of interbedded gypsum and mudstone layers. Fault relationships suggest local shortening during the Early Cretaceous. The Permo-Triassic belt is composed of thick Permian carbonates (Copacabana Formation) and interbedded sandstones, conglomerates and volcanics of the Mitu Formation. This study defines the orientation of

  20. HPV and Genital Warts among Peruvian Men Who Have Sex with Men and Transgender People: Knowledge, Attitudes and Treatment Experiences

    PubMed Central

    Nureña, César R.; Brown, Brandon; Galea, Jerome T.; Sánchez, Hugo; Blas, Magaly M.

    2013-01-01

    Background Several studies have assessed the epidemiology of HPV infection among MSM, but no qualitative studies have specifically assessed how HPV and genital warts (GW) affect South American men who have sex with men (MSM) and male-to-female transgendered women (TG). This study explored the knowledge, attitudes and experiences of Peruvian MSM and TG regarding HPV and GW. Methods We performed a qualitative study consisting of fifteen in-depth interviews and three focus groups carried out in Lima, Peru with diverse MSM and TG groups, including sex workers. Resulting data were analyzed by applying a systematic comparative and descriptive content analysis. Results While knowledge of HPV was limited, awareness of GW was common, particularly among TG persons and sex workers. Still, few participants recognized that GW are sexually transmitted, and many had problems differentiating between GW and other STI/anogenital conditions. Stigmatizing experiences were common during sexual encounters with people who had visible GW. Shame, emotional and physical troubles, and embarrassing sexual experiences were reported by individuals with GW. Search for treatment was mediated by peers, but stigma and apparent health services’ inability to deal with GW limited the access to effective medical care. Conclusions In Peru, public health interventions should strengthen services for HPV/GW management and increase accurate knowledge of the transmission, treatment, and sequelae of HPV/GW in MSM and TG populations. PMID:23516536

  1. Physical features, phenolic compounds, betalains and total antioxidant capacity of coloured quinoa seeds (Chenopodium quinoa Willd.) from Peruvian Altiplano.

    PubMed

    Abderrahim, Fatima; Huanatico, Elizabeth; Segura, Roger; Arribas, Silvia; Gonzalez, M Carmen; Condezo-Hoyos, Luis

    2015-09-15

    Physical features, bioactive compounds and total antioxidant capacity (TAC) of coloured quinoa varieties (Chenopodium quinoa Willd.) from Peruvian Altiplano were studied. Quinoa seeds did not show a pure red colour, but a mixture which corresponded to different fractal colour values (51.0-71.8), and they varied from small to large size. Regarding bioactive compounds, total phenolic (1.23-3.24mg gallic acid equivalents/g) and flavonol contents (0.47-2.55mg quercetin equivalents/g) were highly correlated (r=0.910). Betalains content (0.15-6.10mg/100g) was correlated with L colour parameter (r=-0.569), total phenolics (r=0.703) and flavonols content (r=0.718). Ratio of betaxanthins to betacyanins (0.0-1.41) was negatively correlated with L value (r=-0.744). Whereas, high TAC values (119.8-335.9mmol Trolox equivalents/kg) were negatively correlated with L value (r=-0.779), but positively with betalains (r=0.730), as well as with free (r=0.639), bound (r=0.558) and total phenolic compounds (r=0.676). Unexploited coloured quinoa seeds are proposed as a valuable natural source of phenolics and betalains with high antioxidant capacity.

  2. Plasmodium falciparum malaria in the Peruvian Amazon, a region of low transmission, is associated with immunologic memory.

    PubMed

    Clark, Eva H; Silva, Claudia J; Weiss, Greta E; Li, Shanping; Padilla, Carlos; Crompton, Peter D; Hernandez, Jean N; Branch, OraLee H

    2012-04-01

    The development of clinical immunity to Plasmodium falciparum malaria is thought to require years of parasite exposure, a delay often attributed to difficulties in developing protective antibody levels. In this study, we evaluated several P. falciparum vaccine candidate antigens, including apical membrane antigen 1 (AMA-1), circumsporozoite protein (CSP), erythrocyte binding antigen 175 (EBA-175), and the 19-kDa region of merozoite surface protein 1 (MSP1(19)). After observing a more robust antibody response to MSP1(19), we evaluated the magnitude and longevity of IgG responses specific to this antigen in Peruvian adults and children before, during, and after P. falciparum infection. In this low-transmission region, even one reported prior infection was sufficient to produce a positive anti-MSP1(19) IgG response for >5 months in the absence of reinfection. We also observed an expansion of the total plasmablast (CD19(+) CD27(+) CD38(high)) population in the majority of individuals shortly after infection and detected MSP1-specific memory B cells in a subset of individuals at various postinfection time points. This evidence supports our hypothesis that effective antimalaria humoral immunity can develop in low-transmission regions.

  3. Plasmodium falciparum Malaria in the Peruvian Amazon, a Region of Low Transmission, Is Associated with Immunologic Memory

    PubMed Central

    Clark, Eva H.; Silva, Claudia J.; Weiss, Greta E.; Li, Shanping; Padilla, Carlos; Crompton, Peter D.; Hernandez, Jean N.

    2012-01-01

    The development of clinical immunity to Plasmodium falciparum malaria is thought to require years of parasite exposure, a delay often attributed to difficulties in developing protective antibody levels. In this study, we evaluated several P. falciparum vaccine candidate antigens, including apical membrane antigen 1 (AMA-1), circumsporozoite protein (CSP), erythrocyte binding antigen 175 (EBA-175), and the 19-kDa region of merozoite surface protein 1 (MSP119). After observing a more robust antibody response to MSP119, we evaluated the magnitude and longevity of IgG responses specific to this antigen in Peruvian adults and children before, during, and after P. falciparum infection. In this low-transmission region, even one reported prior infection was sufficient to produce a positive anti-MSP119 IgG response for >5 months in the absence of reinfection. We also observed an expansion of the total plasmablast (CD19+ CD27+ CD38high) population in the majority of individuals shortly after infection and detected MSP1-specific memory B cells in a subset of individuals at various postinfection time points. This evidence supports our hypothesis that effective antimalaria humoral immunity can develop in low-transmission regions. PMID:22252876

  4. Vivid valleys, pallid peaks? Hypsometric variations and rural–urban land change in the Central Peruvian Andes

    PubMed Central

    Haller, Andreas

    2012-01-01

    What happens to the land cover within the hinterland's altitudinal belts while Central Andean cities are undergoing globalization and urban restructuring? What conclusions can be drawn about changes in human land use? By incorporating a regional altitudinal zonation model, direct field observations and GIS analyses of remotely sensed long term data, the present study examines these questions using the example of Huancayo Metropolitano – an emerging Peruvian mountain city of 420,000 inhabitants, situated at 3260 m asl in the Mantaro Valley. The study's results indicate that rapid urban growth during the late 1980s and early 1990s was followed by the agricultural intensification and peri-urban condominization at the valley floor (quechua) – since the beginning of Peru's neoliberal era. Moreover, regarding the adjoining steep slopes (suni) and subsequent grassland ecosystems (puna), the research output presents land cover change trajectories that clearly show an expansion of human land use, such as reforestation for wood production and range burning for livestock grazing, even at high altitudes – despite rural–urban migration trends and contrary to several results of extra-Andean studies. Consequently, rural–urban planners and policy makers are challenged to focus on the manifold impacts of globalization on human land use – at all altitudinal belts of the Andean city's hinterland: toward sustainable mountain development that bridges the social and physical gaps – from the bottom up. PMID:23564987

  5. Exhumation of the Cordillera Blanca batholith (Peruvian Andes) constrained by amphibole barometry and low-temperature thermochronology modelling

    NASA Astrophysics Data System (ADS)

    Margirier, Audrey; Audin, Laurence; Robert, Xavier; Herman, Frédéric; Ganne, Jérôme; Schwartz, Stéphane

    2017-04-01

    The Cordillera Blanca batholith forms the highest Peruvian summits and builds the footwall of the Cordillera Blanca normal fault (CBNF). Even if several models have been proposed, the processes driving both the exhumation of the Cordillera Blanca and extensional deformation along the CBNF are still debated. We coupled barometric and thermochronologic data to quantify the emplacement and exhumation history of the Cordillera Blanca batholith from the late Miocene to present. Based on new thermobarometry data and a compilation of crystallization ages in the Cordillera Blanca batholith, we propose that the batholith was emplaced at a depth of 3 km in successive sills from 12 to 5 Ma. Close to the CBNF, the younger rocks that are emplaced the deepest (i.e., 6 km) are exposed at the surface, suggesting post 5 Ma tilting. In addition, a formal inversion of the barometric and thermochronologic data (apatite fission-track and apatite (U-Th)/He) indicates an increase of the exhumation rates in the Cordillera Blanca during the Quaternary. The higher predicted exhumation rates correlate with areas of high relief suggesting that Quaternary valley carving by glaciations have a significant impact on the latest stage of the Cordillera Blanca exhumation (2-0 Ma).

  6. Waist Circumference, Body Mass Index, and Other Measures of Adiposity in Predicting Cardiovascular Disease Risk Factors among Peruvian Adults

    PubMed Central

    Knowles, K. M.; Paiva, L. L.; Sanchez, S. E.; Revilla, L.; Lopez, T.; Yasuda, M. B.; Yanez, N. D.; Gelaye, B.; Williams, M. A.

    2011-01-01

    Objectives. To examine the extent to which measures of adiposity can be used to predict selected components of metabolic syndrome (MetS) and elevated C-reactive protein (CRP). Methods. A total of 1,518 Peruvian adults were included in this study. Waist circumference (WC), body mass index (BMI), waist-hip ratio (WHR), waist-height ratio (WHtR), and visceral adiposity index (VAI) were examined. The prevalence of each MetS component was determined according to tertiles of each anthropometric measure. ROC curves were used to evaluate the extent to which measures of adiposity can predict cardiovascular risk. Results. All measures of adiposity had the strongest correlation with triglyceride concentrations (TG). For both genders, as adiposity increased, the prevalence of Mets components increased. Compared to individuals with low-BMI and low-WC, men and women with high-BMI and high- WC had higher odds of elevated fasting glucose, blood pressure, TG, and reduced HDL, while only men in this category had higher odds of elevated CRP. Overall, the ROCs showed VAI, WC, and WHtR to be the best predictors for individual MetS components. Conclusions. The results of our study showed that measures of adiposity are correlated with cardiovascular risk although no single adiposity measure was identified as the best predictor for MetS. PMID:21331161

  7. El Niño/La Niña relationship with rainfall at Huancayo, in the Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Kane, R. P.

    2000-01-01

    The major rainy season at Huancayo (central Peruvian Andes) is in the months DJFM (December-March). For years when El Niños were active during these months, two types of effects were noticed. Either there were rainfall deficits in the DJF months, or there were excess rains in DJ, followed and preceded by deficit rains for a month or two. When El Niños were active in other months, the non-rainy season rainfall at Huancayo was sometimes far above average. During years of La Niña (Anti-El Niños), there were often excess rains, in both the rainy and the non-rainy seasons. In coastal Peru, heavy rainfall is considered as one of the criteria for identifying an El Niño. If true, the rainfall patterns at Huancayo are different from those of coastal Peru. In the recent El Niño of 1997, southern Peru had droughts while eastern and northern Peru, Ecuador had floods. The ENSO relationships in different parts of Peru are probably different and need detailed investigation.

  8. The Genetic History of Peruvian Quechua-Lamistas and Chankas: Uniparental DNA Patterns among Autochthonous Amazonian and Andean Populations.

    PubMed

    Sandoval, José R; Lacerda, Daniela R; Acosta, Oscar; Jota, Marilza S; Robles-Ruiz, Paulo; Salazar-Granara, Alberto; Vieira, Pedro Paulo R; Paz-Y-Miño, César; Fujita, Ricardo; Santos, Fabricio R

    2016-03-01

    This study focuses on the genetic history of the Quechua-Lamistas, inhabitants of the Lamas Province in the San Martin Department, Peru, who speak their own distinct variety of the Quechua family of languages. It has been suggested that different pre-Columbian ethnic groups from the Peruvian Amazonia, like the Motilones or "shaven heads", assimilated the Quechua language and then formed the current native population of Lamas. However, many Quechua-Lamistas claim to be direct descendants of the Chankas, a famous pre-Columbian indigenous group that escaped from Inca rule in the Andes. To investigate the Quechua-Lamistas and Chankas' ancestries, we compared uniparental genetic profiles (17 STRs of Q-M3 Y-chromosome and mtDNA complete control region haplotypes) among autochthonous Amazonian and Andean populations from Peru, Bolivia and Ecuador. The phylogeographic and population genetic analyses indicate a fairly heterogeneous ancestry for the Quechua-Lamistas, while they are closely related to their neighbours who speak Amazonian languages, presenting no direct relationships with populations from the region where the ancient Chankas lived. On the other hand, the genetic profiles of self-identified Chanka descendants living in Andahuaylas (located in the Apurimac Department, Peru, in the Central Andes) were closely related to those living in Huancavelica and the assumed Chanka Confederation area before the Inca expansion.

  9. Paleoprecipitation Over North-Eastern Peruvian Andes during the Holocene Inferred by Well Dated δ 18O Speleothem Records

    NASA Astrophysics Data System (ADS)

    Bustamante Rosell, M. G.; Cruz, F. W.; Sifeddine, A.; Cheng, H.; Guyot, J. L.; Strikis, N. M.; Apaéstegui, J. E.; Moquet, J. S.

    2013-12-01

    Two well dated δ18O speleothem records, Sha-2 and Sha-3, were collected from Santa Halana cave, situated in the northeastern flank of Peruvian Andes (2000 m asl) to reconstruct changes in precipitation during the Holocene in the Andes. The results show profound hydroclimatic changes in the early Holocene at this intermediate altitude. Abrupt wet events logged at 9.5 kyr BP and 8.2 kyr BP are synchronous with Bond event 6 and the 8.2 kyrBP cold event, except that the 8.2 kyr BP event is longer than in previous Andean records. During the middle Holocene, the δ18O record indicates gradual precipitation increase following the insolation trend (10°S). This gradual increase is more pronounced in the transition from early to middle Holocene than in spelothem records in lowlands (van Breukelen et al. 2008) and shows a striking similarity with high altitude records, such as the Huascarán ice core. At 6 kyr BP a reorganization of the climatic system seems to occur where the decreasing trend is replaced by high variability in the δ18O that records millennial variability (1200 yr).The millennial variability pattern is synchronous with the occurrence of Bond events in the North Atlantic. However some periods of aridity appear in the record and include a peak of extreme dryness at 6.4 kyr BP and two periods with lower moisture availability at 4.9 and 2.1 kyr BP.

  10. Climate Warming and Soil Carbon in Tropical Forests: Insights from an Elevation Gradient in the Peruvian Andes.

    PubMed

    Nottingham, Andrew T; Whitaker, Jeanette; Turner, Benjamin L; Salinas, Norma; Zimmermann, Michael; Malhi, Yadvinder; Meir, Patrick

    2015-09-01

    The temperature sensitivity of soil organic matter (SOM) decomposition in tropical forests will influence future climate. Studies of a 3.5-kilometer elevation gradient in the Peruvian Andes, including short-term translocation experiments and the examination of the long-term adaptation of biota to local thermal and edaphic conditions, have revealed several factors that may regulate this sensitivity. Collectively this work suggests that, in the absence of a moisture constraint, the temperature sensitivity of decomposition is regulated by the chemical composition of plant debris (litter) and both the physical and chemical composition of preexisting SOM: higher temperature sensitivities are found in litter or SOM that is more chemically complex and in SOM that is less occluded within aggregates. In addition, the temperature sensitivity of SOM in tropical montane forests may be larger than previously recognized because of the presence of "cold-adapted" and nitrogen-limited microbial decomposers and the possible future alterations in plant and microbial communities associated with warming. Studies along elevation transects, such as those reviewed here, can reveal factors that will regulate the temperature sensitivity of SOM. They can also complement and guide in situ soil-warming experiments, which will be needed to understand how this vulnerability to temperature may be mediated by altered plant productivity under future climatic change.

  11. Vivid valleys, pallid peaks? Hypsometric variations and rural-urban land change in the Central Peruvian Andes.

    PubMed

    Haller, Andreas

    2012-11-01

    What happens to the land cover within the hinterland's altitudinal belts while Central Andean cities are undergoing globalization and urban restructuring? What conclusions can be drawn about changes in human land use? By incorporating a regional altitudinal zonation model, direct field observations and GIS analyses of remotely sensed long term data, the present study examines these questions using the example of Huancayo Metropolitano - an emerging Peruvian mountain city of 420,000 inhabitants, situated at 3260 m asl in the Mantaro Valley. The study's results indicate that rapid urban growth during the late 1980s and early 1990s was followed by the agricultural intensification and peri-urban condominization at the valley floor (quechua) - since the beginning of Peru's neoliberal era. Moreover, regarding the adjoining steep slopes (suni) and subsequent grassland ecosystems (puna), the research output presents land cover change trajectories that clearly show an expansion of human land use, such as reforestation for wood production and range burning for livestock grazing, even at high altitudes - despite rural-urban migration trends and contrary to several results of extra-Andean studies. Consequently, rural-urban planners and policy makers are challenged to focus on the manifold impacts of globalization on human land use - at all altitudinal belts of the Andean city's hinterland: toward sustainable mountain development that bridges the social and physical gaps - from the bottom up.

  12. Applicability of the Ricketts' posteroanterior cephalometry for sex determination using logistic regression analysis in Hispano American Peruvians.

    PubMed

    Perez, Ivan; Chavez, Allison K; Ponce, Dario

    2016-01-01

    The Ricketts' posteroanterior (PA) cephalometry seems to be the most widely used and it has not been tested by multivariate statistics for sex determination. The objective was to determine the applicability of Ricketts' PA cephalometry for sex determination using the logistic regression analysis. The logistic models were estimated at distinct age cutoffs (all ages, 11 years, 13 years, and 15 years) in a database from 1,296 Hispano American Peruvians between 5 years and 44 years of age. The logistic models were composed by six cephalometric measurements; the accuracy achieved by resubstitution varied between 60% and 70% and all the variables, with one exception, exhibited a direct relationship with the probability of being classified as male; the nasal width exhibited an indirect relationship. The maxillary and facial widths were present in all models and may represent a sexual dimorphism indicator. The accuracy found was lower than the literature and the Ricketts' PA cephalometry may not be adequate for sex determination. The indirect relationship of the nasal width in models with data from patients of 12 years of age or less may be a trait related to age or a characteristic in the studied population, which could be better studied and confirmed.

  13. [Skin cancer and sun radiation: peruvian experience in the prevention and early detection of skin cancer and melanoma].

    PubMed

    Sordo, Carlos; Gutiérrez, César

    2013-03-01

    The excessive exposure to sun radiation, especially to ultraviolet radiation (UV), has led to various diseases, in particular to skin cancer. In 1995, the Peruvian Dermatological Association conducted the first "Campaign for Education, Prevention and Early Detection of Skin Cancer and Melanoma" called "Mole's Day". The Ministry of Health has turned it into an official event, and the Health Social Security (EsSalud) also participates. This is a free campaign that takes place every year nationwide. 118,092 people attended from 1995 to 2011 in 76 sites distributed in 18 cities throughout the country. A cutaneous lesion were malignancy was suspected was identified in 2.8% of people attending, out of which 64.9% corresponded to basal cell carcinoma, 26.7% to cutaneous melanoma, and 8.4% to squamous cell carcinoma. These campaigns are highly important not only because of the assistance given, but also because of the educational activities aimed at promoting a prevention culture in favor of the most vulnerable populations. Finally, we believe it is important to continue educating the population on skin cancer prevention, to build awareness among the authorities so that they actively participate in the performance of these activities, and to ask all physicians to coordinately join this initiative, in order to continue growing, and to improve all that has been attained for the benefit of our country.

  14. Climate Warming and Soil Carbon in Tropical Forests: Insights from an Elevation Gradient in the Peruvian Andes

    PubMed Central

    Nottingham, Andrew T.; Whitaker, Jeanette; Turner, Benjamin L.; Salinas, Norma; Zimmermann, Michael; Malhi, Yadvinder; Meir, Patrick

    2015-01-01

    The temperature sensitivity of soil organic matter (SOM) decomposition in tropical forests will influence future climate. Studies of a 3.5-kilometer elevation gradient in the Peruvian Andes, including short-term translocation experiments and the examination of the long-term adaptation of biota to local thermal and edaphic conditions, have revealed several factors that may regulate this sensitivity. Collectively this work suggests that, in the absence of a moisture constraint, the temperature sensitivity of decomposition is regulated by the chemical composition of plant debris (litter) and both the physical and chemical composition of preexisting SOM: higher temperature sensitivities are found in litter or SOM that is more chemically complex and in SOM that is less occluded within aggregates. In addition, the temperature sensitivity of SOM in tropical montane forests may be larger than previously recognized because of the presence of “cold-adapted” and nitrogen-limited microbial decomposers and the possible future alterations in plant and microbial communities associated with warming. Studies along elevation transects, such as those reviewed here, can reveal factors that will regulate the temperature sensitivity of SOM. They can also complement and guide in situ soil-warming experiments, which will be needed to understand how this vulnerability to temperature may be mediated by altered plant productivity under future climatic change. PMID:26955086

  15. Self-esteem in adolescents with Angle Class I, II and III malocclusion in a Peruvian sample.

    PubMed

    Florián-Vargas, Karla; Honores, Marcos J Carruitero; Bernabé, Eduardo; Flores-Mir, Carlos

    2016-01-01

    To compare self-esteem scores in 12 to 16-year-old adolescents with different Angle malocclusion types in a Peruvian sample. A cross-sectional study was conducted in a sample of 276 adolescents (159, 52 and 65 with Angle Class I, II and III malocclusions, respectively) from Trujillo, Peru. Participants were asked to complete the Rosenberg Self-Esteem Scale (RSES) and were also clinically examined, so as to have Angle malocclusion classification determined. Analysis of covariance (ANCOVA) was used to compare RSES scores among adolescents with Class I, II and III malocclusions, with participants' demographic factors being controlled. Mean RSES scores for adolescents with Class I, II and III malocclusions were 20.47 ± 3.96, 21.96 ± 3.27 and 21.26 ± 4.81, respectively. The ANCOVA test showed that adolescents with Class II malocclusion had a significantly higher RSES score than those with Class I malocclusion, but there were no differences between other malocclusion groups. Supplemental analysis suggested that only those with Class II, Division 2 malocclusion might have greater self-esteem when compared to adolescents with Class I malocclusion. This study shows that, in general, self-esteem did not vary according to adolescents' malocclusion in the sample studied. Surprisingly, only adolescents with Class II malocclusion, particularly Class II, Division 2, reported better self-esteem than those with Class I malocclusion. A more detailed analysis assessing the impact of anterior occlusal features should be conducted.

  16. Comparative evaluation of the DNA damage response in two Peruvian marine bivalves exposed to changes in temperature

    NASA Astrophysics Data System (ADS)

    Sotil, Giovanna; Tarazona, Juan; Alvis, Rafael; Francia, Juan C.; Shiga, Betty

    2008-03-01

    The comparison of temperature responses of two mytilids from the high ( Brachidontes purpuratus) and low ( Semimytilus algosus) intertidal zone of the Peruvian coast was carried out focusing on the production of micronucleus and nuclear abnormalities in gill tissue. Two temperatures (23 and 11°C) were evaluated, in presence of three mitomycin C concentrations as a stressor (0.02, 0.04 and 0.06 × 10-6), simulating hypothetical El Niño and La Niña conditions. Responses to extreme temperatures between both species were significantly different ( P = 0.008). Frequency of micronuclei and nuclear abnormalities in S. algosus did not differ statistically among the temperature treatments, whereas in B. purpuratus there was an observed significant decrease in nuclear abnormalities ( P = 0.012) and micronuclei frequencies ( P = 0.002) between both temperature treatments. The low frequency of micronuclei observed at high temperature and mitomycin C suggests a better efficiency to stress resistance, as occurs during El Niño events, of the species from the higher intertidal zone of B. purpuratus compared to S. algosus from the lower intertidal zone.

  17. Variations of the electromagnetic field that preceded the Peruvian M7.0 earthquake occurred on September 25, 2013

    NASA Astrophysics Data System (ADS)

    Cataldi, Daniele; Cataldi, Gabriele; Straser, Valentino

    2014-05-01

    Through this work we want to highlight the existence of strong electromagnetic emission in the ELF band that preceded the M7, 0 earthquake occurred in Peru on September 25, 2013 at 16:42:42 UTC. The electromagnetic activity data were provided by the monitoring station of Radio Emissions Project (Cecchina, Albano Laziale, Rome, Italy). The monitoring of electromagnetic field takes place 24H24, 7 days on 7, through a prototype of a ELF radio receiver (gain = 57dB) connected to a loop antenna with diameter of 1x1 meters (square section) and contains 25 turns. The antenna is oriented at 306° NW. The data on M7, 0 earthquakes were provided by USGS. The monitoring station has detected intense impulsive emissions starting from 13:55 UTC until, approximately, to 16:40 UTC. These emissions have a very high intensity and have shown just a few hours before the M7.0 earthquake. Seeing as have not been registered radio emission of this intensity for more than 24 before, we think that these signals can be associated with the Peruvian earthquake. Radio emissions with these characteristics have been recorded many times by the monitoring station of Radio Emissions Project, and in all cases have preceded of some hours the M6+ seismic events occurred on a global scale. Key words: Earthquake prediction, ELF, Seismic Electromagnetic Precursor (SEP), Seismic Geomagnetic Precursor (SGP), Geomagnetic emissions.

  18. Applicability of the Ricketts’ posteroanterior cephalometry for sex determination using logistic regression analysis in Hispano American Peruvians

    PubMed Central

    Perez, Ivan; Chavez, Allison K.; Ponce, Dario

    2016-01-01

    Background: The Ricketts' posteroanterior (PA) cephalometry seems to be the most widely used and it has not been tested by multivariate statistics for sex determination. Objective: The objective was to determine the applicability of Ricketts' PA cephalometry for sex determination using the logistic regression analysis. Materials and Methods: The logistic models were estimated at distinct age cutoffs (all ages, 11 years, 13 years, and 15 years) in a database from 1,296 Hispano American Peruvians between 5 years and 44 years of age. Results: The logistic models were composed by six cephalometric measurements; the accuracy achieved by resubstitution varied between 60% and 70% and all the variables, with one exception, exhibited a direct relationship with the probability of being classified as male; the nasal width exhibited an indirect relationship. Conclusion: The maxillary and facial widths were present in all models and may represent a sexual dimorphism indicator. The accuracy found was lower than the literature and the Ricketts' PA cephalometry may not be adequate for sex determination. The indirect relationship of the nasal width in models with data from patients of 12 years of age or less may be a trait related to age or a characteristic in the studied population, which could be better studied and confirmed. PMID:27555732

  19. Direct Detection of Vibrio cholerae and ctxA in Peruvian Coastal Water and Plankton by PCR

    PubMed Central

    Lipp, Erin K.; Rivera, Irma N. G.; Gil, Ana I.; Espeland, Eric M.; Choopun, Nipa; Louis, Valérie R.; Russek-Cohen, Estelle; Huq, Anwar; Colwell, Rita R.

    2003-01-01

    Seawater and plankton samples were collected over a period of 17 months from November 1998 to March 2000 along the coast of Peru. Total DNA was extracted from water and from plankton grouped by size into two fractions (64 μm to 202 μm and >202 μm). All samples were assayed for Vibrio cholerae, V. cholerae O1, V. cholerae O139, and ctxA by PCR. Of 50 samples collected and tested, 33 (66.0%) were positive for V. cholerae in at least one of the three fractions. Of these, 62.5% (n = 32) contained V. cholerae O1; ctxA was detected in 25% (n = 20) of the V. cholerae O1-positive samples. None were positive for V. cholerae O139. Thus, PCR was successfully employed in detecting toxigenic V. cholerae directly in seawater and plankton samples and provides evidence for an environmental reservoir for this pathogen in Peruvian coastal waters. PMID:12788781

  20. Primate abundance and habitat preferences on the lower Urubamba and Tambo rivers, central-eastern Peruvian Amazonia.

    PubMed

    Aquino, Rolando; Cornejo, Fanny M; Heymann, Eckhard W

    2013-10-01

    We report information on population density, group size, and habitat preferences of primates along the lower Río Urubamba and in the Río Urubamba-Río Tambo interfluvium, in central-eastern Peruvian Amazonia, an area that has been little explored with regard to its primate fauna. During 425 km of transect walks in October-November 2008 and April-May 2009 totally 174 groups of nine primate species were encountered, the most common being Callicebus brunneus (45 groups), Saguinus imperator (41 groups), and Aotus nigriceps (26 groups). Group sizes were smallest for A. nigriceps and C. brunneus (mean of 2.8 and 2.9, respectively) and largest for Saimiri boliviensis (mean 15.6). Population densities were lowest for Lagothrix cana (3.3 individuals/km(2)) and highest for A. nigriceps (31.1 individuals/km(2)). Groups of C. brunneus, S. imperator, S. boliviensis, Cebus albifrons, and Cebus apella were most frequently (83 % of sightings) encountered in semi-dense or in open primary forest that included stands of bamboo (Guadua sarcocarpa) or where bamboo was a very common species.

  1. Oxygen isotope record of the 1997-1998 El Niño in Peruvian sea catfish (Galeichthys peruvianus) otoliths

    NASA Astrophysics Data System (ADS)

    Andrus, C. Fred T.; Crowe, Douglas E.; Romanek, Christopher S.

    2002-12-01

    Sagittal otoliths of the Peruvian sea catfish Galeichthys peruvianus were collected from the north coast of Peru during and after the 1997-1998 El Niño. The otoliths were analyzed via laser microprobe and micromilling techniques for oxygen isotope composition through ontogeny to document their use as an El Niño-Southern Oscillation (ENSO) proxy. Results were compared to theoretical calculations for the δ18O of otolith aragonite using measured sea surface temperatures (SST) and δ18O values for local seawater assuming equilibrium oxygen isotope fractionation was achieved. All otoliths recorded the 1997-1998 El Niño event as well as seasonal temperature variations. These ENSO events were recorded in otolith aragonite as significant negative excursions in δ18O that reflected the increased temperature of local marine waters. The combined otolith data were used to create a 10-year SST record, including ENSO events and local seasonal temperature variation, validating the use of otolith δ18O as a temperature proxy.

  2. Epidemiology and Genetic Characterization of Noroviruses among Adults in an Endemic Setting, Peruvian Amazon Basin, 2004–2011

    PubMed Central

    Ballard, Sarah-Blythe; Reaves, Erik J.; Luna, C. Giannina; Silva, Maria E.; Rocha, Claudio; Heitzinger, Kristen; Saito, Mayuko; Apaza, Sonia; Espetia, Susan; Blazes, David L.; Tilley, Drake H.; Guzmán Aguilar, Rene C.; Gilman, Robert H.; Bausch, Daniel G.

    2015-01-01

    Background Successful vaccination strategies against norovirus will require understanding the burden of disease and relevant genotypes in populations. However, few data are available from cohort studies of adults living in low- and middle-income countries (LMIC). Materials and Methods We conducted a nested case-control study within a Peruvian military cohort to characterize the burden of norovirus infection, predominant genotypes, and associated symptoms from 2004 through 2011. Randomly selected case and control stools were tested for norovirus, bacteria, and parasites. The odds ratio of the association between norovirus infection and diarrhea was estimated using multiple logistic regression and co-infection adjusted attributable fractions were calculated. Results Of the 3,818 cohort study participants, 624 developed diarrhea. Overall and norovirus-associated diarrhea incidence rates were 42.3 and 6.0 per 100 person-years, respectively. The most prevalent norovirus genogroup was GII (72.5%, 29/40), which was associated with diarrhea (AOR 3.4, 95% CI: 1.3–8.7, P = 0.012). The co-infection adjusted GII attributable fraction was 6.4%. Discussion Norovirus was a frequent cause of diarrhea in an adult population followed longitudinally in an LMIC setting. Vaccine strategies should consider targeting adults in endemic settings and special populations that could serve as community transmission sources. PMID:26161556

  3. The Genetic History of Peruvian Quechua‐Lamistas and Chankas: Uniparental DNA Patterns among Autochthonous Amazonian and Andean Populations

    PubMed Central

    Sandoval, José R.; Lacerda, Daniela R.; Acosta, Oscar; Jota, Marilza S.; Robles‐Ruiz, Paulo; Salazar‐Granara, Alberto; Vieira, Pedro Paulo R.; Paz‐y‐Miño, César; Fujita, Ricardo

    2016-01-01

    Summary This study focuses on the genetic history of the Quechua‐Lamistas, inhabitants of the Lamas Province in the San Martin Department, Peru, who speak their own distinct variety of the Quechua family of languages. It has been suggested that different pre‐Columbian ethnic groups from the Peruvian Amazonia, like the Motilones or “shaven heads”, assimilated the Quechua language and then formed the current native population of Lamas. However, many Quechua‐Lamistas claim to be direct descendants of the Chankas, a famous pre‐Columbian indigenous group that escaped from Inca rule in the Andes. To investigate the Quechua‐Lamistas and Chankas’ ancestries, we compared uniparental genetic profiles (17 STRs of Q‐M3 Y‐chromosome and mtDNA complete control region haplotypes) among autochthonous Amazonian and Andean populations from Peru, Bolivia and Ecuador. The phylogeographic and population genetic analyses indicate a fairly heterogeneous ancestry for the Quechua‐Lamistas, while they are closely related to their neighbours who speak Amazonian languages, presenting no direct relationships with populations from the region where the ancient Chankas lived. On the other hand, the genetic profiles of self‐identified Chanka descendants living in Andahuaylas (located in the Apurimac Department, Peru, in the Central Andes) were closely related to those living in Huancavelica and the assumed Chanka Confederation area before the Inca expansion. PMID:26879156

  4. Epidemiology and Genetic Characterization of Noroviruses among Adults in an Endemic Setting, Peruvian Amazon Basin, 2004-2011.

    PubMed

    Ballard, Sarah-Blythe; Reaves, Erik J; Luna, C Giannina; Silva, Maria E; Rocha, Claudio; Heitzinger, Kristen; Saito, Mayuko; Apaza, Sonia; Espetia, Susan; Blazes, David L; Tilley, Drake H; Guzmán Aguilar, Rene C; Gilman, Robert H; Bausch, Daniel G

    2015-01-01

    Successful vaccination strategies against norovirus will require understanding the burden of disease and relevant genotypes in populations. However, few data are available from cohort studies of adults living in low- and middle-income countries (LMIC). We conducted a nested case-control study within a Peruvian military cohort to characterize the burden of norovirus infection, predominant genotypes, and associated symptoms from 2004 through 2011. Randomly selected case and control stools were tested for norovirus, bacteria, and parasites. The odds ratio of the association between norovirus infection and diarrhea was estimated using multiple logistic regression and co-infection adjusted attributable fractions were calculated. Of the 3,818 cohort study participants, 624 developed diarrhea. Overall and norovirus-associated diarrhea incidence rates were 42.3 and 6.0 per 100 person-years, respectively. The most prevalent norovirus genogroup was GII (72.5%, 29/40), which was associated with diarrhea (AOR 3.4, 95% CI: 1.3-8.7, P = 0.012). The co-infection adjusted GII attributable fraction was 6.4%. Norovirus was a frequent cause of diarrhea in an adult population followed longitudinally in an LMIC setting. Vaccine strategies should consider targeting adults in endemic settings and special populations that could serve as community transmission sources.

  5. A Phase One Safety Study of Lactobacillus reuteri Conducted in the Peruvian Amazon: Observations from the Field

    PubMed Central

    Oberhelman, Richard A.; Kosek, Margaret N.; Peñataro-Yori, Pablo; Paredes-Olórtegui, Maribel; Connolly, Eamonn

    2014-01-01

    Clinical research on probiotics presents challenging issues for researchers, regulators, and funding agencies, and these issues become more complex when United States federally funded research is conducted outside the United States. Here, we describe the design and results of a Phase I safety study of Lactobacillus reuteri DSM 17938 conducted as a community-based trial under the Food and Drug Administration Investigative New Drug (FDA IND) program in a small town in the Peruvian Amazon. Forty-five healthy adults 18 to 65 years of age were randomized in a 2:1 ratio to receive either Lactobacillus reuteri 108 organisms once daily for 5 days or an identical appearing placebo. Results showed no evidence of invasive infection resulting from probiotic administration and no differences between groups. Although we encountered several challenges in conducting an FDA-approved safety trial in this setting, the rigorously collected contextually relevant data will be very valuable to support later Phase II/III studies of L. reuteri for use in similar settings. PMID:24515943

  6. Biochemical and immunological characteristics of Peruvian Loxosceles laeta spider venom: neutralization of its toxic effects by anti-loxoscelic antivenoms.

    PubMed

    Guimarães, G; Dias-Lopes, C; Duarte, C G; Felicori, L; Machado de Avila, R A; Figueiredo, L F M; de Moura, J; Faleiro, B T; Barro, J; Flores, K; Silva, W; Tintaya, B; Yarleque, A; Bonilla, C; Kalapothakis, E; Salas, C E; Chávez-Olortegui, C

    2013-08-01

    This manuscript describes the general biochemical properties and immunological characteristics of Peruvian spider Loxosceles laeta venom (PLlv), which is responsible for the largest number of accidents involving venomous animals in Peru. In this work, we observed that the venom of this spider is more lethal to mice when compared with L. laeta venom from Brazil (BLlv). The LD₅₀ of PLlv was 1.213 mg/kg when the venom was intradermally injected. The venom displayed sphingomyelinase activity and produced dermonecrotic, hemorrhagic and edema effects in rabbits. 2-D SDS-PAGE separation of the soluble venoms resulted in a protein profile ranging from 20 to 205 kDa. Anti-PLlv and anti-BLlv sera produced in rabbits and assayed by ELISA showed that rabbit antibodies cross-reacted with PLlv and BLlv and also with other Brazilian Loxosceles venoms. Western blotting analysis showed that bands corresponding to 25-35 kDa are the proteins best recognized in every Loxosceles spp venoms analyzed. The immunized rabbits displayed protective effect after challenge with PLlv and BLlv. In vitro assays with horse anti-loxoscelic antivenoms produced in Brazil and Peru demonstrated that these commercial antivenoms were efficient to inhibit the sphingomyelinase activity of PLlv and BLlv. Copyright © 2013 Elsevier Ltd. All rights reserved.

  7. Association of vectors and environmental conditions during the emergence of Peruvian horse sickness orbivirus and Yunnan orbivirus in northern Peru.

    PubMed

    Méndez-López, María R; Attoui, Houssam; Florin, David; Calisher, Charles H; Florian-Carrillo, J Christian; Montero, Stephanie

    2015-12-01

    Since 1983, cases of diseased donkeys and horses with symptoms similar to those produced by alphaviruses were identified in two departments in northern Peru; however serological testing ruled out the presence of those viruses and attempts to isolate an agent were also unproductive. In 1997, also in northern Peru, two new orbiviruses were discovered, each recognized as a causative agent of neurological diseases in livestock and domestic animals and, at the same time, mosquitoes were found to be infected with these viruses. Peruvian horse sickness virus (PHSV) was isolated from pools of culicid mosquitoes, Aedes serratus and Psorophora ferox, and Yunnan virus (YUOV) was isolated from Aedes scapularis in the subtropical jungle (upper jungle) located on the slope between the east side of the Andes and the Amazonian basin in the Department of San Martín. Both viruses later were recovered from mosquitoes collected above the slope between the west side of the Andes and the coast (Department of Piura) in humid subtropical areas associated with the Piura River basin. In this region, PHSV was isolated from Anopheles albimanus and YUOV was isolated from Ae. scapularis. We discuss the ecology of vector mosquitoes during the outbreaks in the areas where these mosquitoes were found. © 2015 The Society for Vector Ecology.

  8. Nitrogen and Carbon Cycling in Deforested and Pristine Upland (2400m) Forest Catchments in the Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Townsend-Small, A.; Haberer, J.; McClain, M.; Ramos, O.; Gardner, W.; McCarthy, M.; Brandes, J.

    2001-12-01

    Nitrogen and carbon cycling were examined within two upland (2400m) forest catchments in the Peruvian Andes. One catchment was partially deforested within the last 3 years, while the other has remained untouched. Tracer amended samples were analyzed to determine the pathways and rates of nitrogen cycling in streams draining each catchment. Both streams exhibited very low inorganic nitrogen levels, on the order of 1 to 2 uM. A large percentage (>1/3) of the total fixed nitrogen flux from these systems was in the form of particulates. Preliminary results suggest a very high rate of nitrogen cycling in these systems. Isotopic measurements of plant samples from both catchments also suggest that these forests are highly efficient in trapping and using atmospheric nitrogen sources. The partially deforested catchment had significantly more species using C4 and CAM carbon fixation pathways. Leaf litter from both streams and leaves from trees in the area were also analyzed for carbon and nitrogen isotopes to compare and contrast nitrogen and carbon cycling between the two sites. This and other data to be presented suggest that deforestation has subtle but significant effects upon the ability of tropical upland forests to retain and use nutrients.

  9. Relevance of future snowfall level height in the Peruvian Andes for glacier loss in the 21st century under different emission scenarios

    NASA Astrophysics Data System (ADS)

    Schauwecker, Simone; Kronenberg, Marlene; Rohrer, Mario; Huggel, Christian; Endries, Jason; Montoya, Nilton; Neukom, Raphael; Perry, Baker; Salzmann, Nadine; Schwarb, Manfred; Suarez, Wilson

    2017-04-01

    In many regions of Peru, the competition for limited hydrological resources already represents a large risk for conflicts. In this context, and within the circumstances of climate change, there is a great interest in estimating the future loss of Peruvian glaciers. Solid precipitation on glaciers, which affects the shortwave radiation budget via its effects on albedo, in general reduces ablation. For that reason, the height of the upper level of the transition zone between liquid and solid precipitation (snowfall level height) is considered to play a critical role. This snowfall level height is linked to air temperature. The observed and projected warming of the atmosphere is therefore affecting the glaciers amongst others by changing the snowfall level height. Despite the potential significance of these changes for Peruvian glaciers, the relations between snowfall level heights, glacier extents and climate scenarios have been poorly investigated so far. In our study, we first analyse the snowfall level heights over the Peruvian Cordilleras. Second, we investigate the relationship between the present snowfall level heights and current glacier extents. As a third step, we derive projected changes of snowfall level heights from GCMs for the RCP2.6 and 8.5 emission scenarios and use them to roughly estimate the end of XXI century glaciation for the Peruvian Cordilleras. Our results indicate a large difference in future glacier extent between the high-emission (pessimistic) RCP8.5 and the low-emission (optimistic) RCP2.6. If global emissions can be substantially reduced, a significant part of the glaciated area of Peru can be maintained. On the contrary, if mitigation is unsuccessful, most of the glacier mass in Peru will be lost during the 21st century. In both cases, but even more so for the high-emission scenario, adaptation will play a critical role and should focus on improvements in water resource management which is essential on a local to regional scale. Air

  10. Pedological and mineralogical investigations on a soil-paleosoil sequence within Andosols in the Western Cordillera of the Peruvian Andes (region Laramate, 14.5S)

    NASA Astrophysics Data System (ADS)

    Leceta Gobitz, Fernando; Mächtle, Bertil; Schukraft, Gerd; Meyer, Hans-Peter; Eitel, Bernhard

    2016-04-01

    An integrated research project of environmental sciences focuses on a group of four Andosol profiles in Western flank of the Peruvian southern Andes. Aim of this study is to contribute to the reconstruction of the paleo environmental conditions in the Western Cordillera of the Peruvian Andes. Standard pedological and sedimentological analysis has been conducted in order to identify morphological and geochemical features generated by climatic variations during the middle and late Holocene. Though a provenance analysis of sediments, all potential lithological sources around the town of Laramate are being examined under the scanning electron microscope, in order to find significant mineralogical associations downward the soil-profile. Preliminary results reveal two edaphic cycles within a soil-paleo soil-sequence: a relative poor developed "Ah" topsoil, mostly composed by fine grain sediments, is underlain by a well preserved "2Ah" paleo soil; a "2Bwt" subsoil exhibits signs of alteration and clay translocation; parent material in slight weathered statement at "2C" culminates the sequence. Mineralogical analytical data supports the premise, that materials in the uppermost horizons are relatable to distal geological units of the Western and Eastern Cordillera, therefore also related to other described aeolian archives from the region: "Desert Margin Loess" at the Andean foot-zone and "Mixed Loess" in the Puna grassland. The amphibole varieties Actinolite, Mg-Hornblende and Edenite could be only distinguished within the soil sediments. The fluvial transport to its current position is excluded, insofar mentioned varieties stem from the granodiorites of Coastal Batholite (downstream the study area), and the vulcanites of the Anta und Andahuaylas Formation (eastward the continental divide). References: Eitel, B., et al. (2005). "Geoarchaeological evidence from desert loess in the Nazca-Palpa region, southern Peru : Palaeoenvironmental changes and their impact on Pre

  11. Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study.

    PubMed

    Rosas-Aguirre, Angel; Guzman-Guzman, Mitchel; Gamboa, Dionicia; Chuquiyauri, Raul; Ramirez, Roberson; Manrique, Paulo; Carrasco-Escobar, Gabriel; Puemape, Carmen; Llanos-Cuentas, Alejandro; Vinetz, Joseph M

    2017-08-04

    Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and epidemiological survey was conducted in September-October 2012, as a baseline underlying a 3-year population-based longitudinal cohort study. The aim was to characterize malaria transmission patterns in two contrasting ecological rural sites in the Peruvian Amazon, Lupuna (LUP), a riverine environment, and Cahuide (CAH), associated with road-linked deforestation. After a full population census, 1941 individuals 3 years and older (829 in LUP, 1112 in CAH) were interviewed, clinically examined and had a blood sample taken for the detection of malaria parasites by microscopy and PCR. Species-specific parasite prevalence was estimated overall and by site. Multivariate logistic regression models assessed risk factors for parasite infection by PCR, while SaTScan detected spatial clusters of PCR-positive individuals within each site. In addition, data from routine malaria surveillance in the period 2009-2012 were obtained. Parasite prevalence by PCR was higher in CAH than in LUP for Plasmodium vivax (6.2% vs. 3.9%) and for Plasmodium falciparum (2.6% vs. 1.2%). Among PCR-confirmed infections, asymptomatic (Asy) parasite carriers were always more common than symptomatic (Sy) infections for P. vivax (Asy/Sy ratio: 2/1 in LUP and 3.7/1 in CAH) and for P. falciparum (Asy/Sy ratio: 1.3/1 in LUP and 4/1 in CAH). Sub-patent (Spat) infections also predominated over patent (Pat) infections for both species: P. vivax (Spat/Pat ratio: 2.8/1 in LUP and 3.7/1 in CAH) and P. falciparum malaria (Spat/Pat ratio: 1.9/1 in LUP and 26/0 in CAH). For CAH, age, gender and living in a household without electricity were significantly associated with P. vivax infection, while only age and living in a household with electricity was associated with P. falciparum infection. For LUP, only

  12. Characterizing Seismic Anisotropy across the Peruvian Flat-Slab Subduction Zone: Implications for the Dynamics of Flat-Slabs

    NASA Astrophysics Data System (ADS)

    Eakin, Caroline; Long, Maureen; Beck, Susan; Wagner, Lara; Tavera, Hernando

    2014-05-01

    Although 10% of subduction zones worldwide today exhibit shallow or flat subduction, we are yet to fully understand how and why these slabs go flat. An excellent study location for such a problem is in Peru, where the largest region of flat-subduction currently exists, extending ~1500 km in length (from 3 °S to 15 °S) and ~300 km in width. Across this region we investigate the pattern of seismic anisotropy, an indicator for past and/or ongoing deformation in the upper mantle. To achieve this we conduct shear wave splitting analyzes at 40 broadband stations from the PULSE project (PerU Lithosphere and Slab Experiment). These stations were deployed for 2+ years across the southern half of the Peruvian flat-slab region. We present detailed shear wave splitting results for both teleseismic events (such as SKS, SKKS, PKS, sSKS) that sample the upper mantle column beneath the stations as well as direct S from local events that constrain anisotropy in the upper portion of the subduction zone. We analyze the variability of our results with respect to initial polarizations, ray paths, and frequency content as well as spatial variability between stations as the underlying slab morphology changes. Teleseismic results show predominately NW-SE fast polarizations (trench oblique to sub-parallel) over the flat-slab region east of Lima. These results are consistent with observations of more complex multi-layered anisotropy beneath a nearby permanent station (NNA) that suggests a trench-perpendicular fast direction in the lowest layer in the sub-slab mantle. Further south, towards the transition to steeper subduction, the splitting pattern becomes increasingly dominated by null measurements. Over to the east however, beyond Cuzco, where the mantle wedge might begin to play a role, we record fast polarizations quasi-parallel to the local slab contours. Local S results indicate the presence of weak (delay times typically less than 0.5 seconds) and heterogeneous supra

  13. High-Resolution ∂18O record of middle-late Holocene hydrologic variability from the central Peruvian Andes (Invited)

    NASA Astrophysics Data System (ADS)

    Rodbell, D. T.; Abbott, M.; Bird, B. W.; Stansell, N.

    2009-12-01

    Laguna Yuraicocha in the western cordillera of the central Peruvian Andes (12.53°S; 75.50°W; 4460 masl) is dammed by late glacial moraines and is underlain and surrounded by Jurassic and Cretaceous limestone interbedded with siliciclastic rocks. A 6.9 meter-long sediment core from the distal end of the lake is dominated by authigenic calcite (marl) with a mean concentration of 82 weight percent that has accumulated at a rate of ~ 1 mm yr-1 for the past 6200 years. The age model for the core is based on a combination of 210Pb and AMS 14C ages from charcoal; modern lake water is ~1‰ evaporatively enriched from mean regional precipitation. Marl samples were taken with an average sampling interval of 8 years; samples were treated to remove organic matter, sieved to concentrate the <75 µm fraction, and the clay fraction was removed by repeated pipette withdrawal. The <75 µm fraction contains abundant euhedral grains of calcite that are not abraded or corroded, thus reflecting their authigenic origin in Laguna Yuraicocha. The 18O and 13C stratigraphy reveals decadal, century, and millennial-scale variability that is comparable to isotope records from other carbonate lakes and ice cores in the region. The 18O and 13C records generally covary with similar amplitudes; δ13C ranges from -0.5 to 3.5 ‰ (PDB). A pronounced linear trend of δ18O depletion (from -10.5 to -14.5 ‰) spans the length of record and likely reflects a progressive increase in hydrologic balance (i.e., the ratio of precipitation/evaporation) through the middle and late Holocene. This interpretation is consistent with basal core sediment that records pronounced lake low stands, and possible periodic dessication in the early-middle Holocene. The last 1200 yr of record reveals a 2‰ depletion culminating with the most depleted isotopes on record ~ AD 1800 followed by an abrupt 1.5 ‰ enrichment that began ~AD 1900 and continues to the present. These trends match closely the 18O record from the

  14. The Role of Subducting Ridges in the Formation of Flat Slabs: Insights from the Peruvian Flat Slab

    NASA Astrophysics Data System (ADS)

    Knezevic Antonijevic, Sanja; Wagner, Lara; Kumar, Abhash; Beck, Susan; Long, Maureen; Zandt, George; Eakin, Caroline M.

    2015-04-01

    Flattening of the subducting plate is often used to explain various geological features removed far from the subducting margins, including basement-cored uplifts, the cessation of arc volcanism, ignimbrite flare-ups, and the formation of high plateaus and ore deposits [Humphreys et al., 2003; Gutscher et al., 2000; Rosenbaum et al., 2005, Kay and Mpodozis, 2001]. Today, flat slab subduction is observed in central Chile and Peru, representing the modern analogues to the immense paleo-flat slab that subducted beneath the North American continent during the Laramide orogeny (80-55 Ma) [English et al., 2003]. However, how flat slabs form and what controls their inboard and along-strike extent is still poorly understood. To better understand modern and paleo-flat slabs, we focus on the Peruvian flat slab, where the Nazca plate starts to bend at ~90 km depth and travels horizontally for several hundred kilometers beneath the South American plate. Earlier studies propose a correlation between the flat slab and the subducting Nazca Ridge that has been migrating to the south over the past 11 ~Ma [Hampel et al., 2004, Gutscher et al., 2003]. Combining 3D shear wave velocity structure and Rayleigh wave phase anisotropy between ~10° and 18° S, we find that the flat slab has the greatest inboard extent along the track of the subducting Nazca Ridge. North of the ridge track, where the flat slab was initially formed, the flat slab starts to sag, tear and re-initiate steep slab subduction, allowing inflow of warm asthenosphere. Based on our new constraints on the geometry of the subducted plate, we find that the subduction of buoyant oceanic features with overthickened oceanic crust plays a vital role in the formation of flat slabs. We further develop a model of temporal evolution of the Peruvian flab slab that forms as a result of the combined effects of the subducting ridge, trench retreat, and suction forces. Once the buoyant ridge subducts to ~90 km depth, it will fail to

  15. HTLV-I infection is not associated with a higher risk of death in Peruvian HIV-infected patients.

    PubMed

    Collins, Jaime A; Hernández, Adrián V; Hidalgo, José A; Salazar, Raúl

    2009-01-01

    Limited and contradictory information exists regarding the prognosis of HIV/HTLV-I co-infection. Our goal was to estimate the effect of HTLV-I infection on mortality in HIV-infected patients at a HIV reference center in Peru. We studied a retrospective cohort of HIV-infected patients, who were exposed or unexposed to HTLV-I. Exposed patients were Western Blot (WB) positive for both retroviruses. Unexposed patients were WB positive for HIV, and had least one negative EIA for HTLV-I. These were selected among patients who entered our Program immediately before and after each exposed patient, between January 1990 and June 2004. Survival time was considered between the diagnosis of exposure to HTLV-I and death or censoring. Confounding variables were age, gender, baseline HIV clinical stage, baseline CD4+ T cell count, and antiretroviral therapy. We studied 50 exposed, and 100 unexposed patients. Exposed patients had a shorter survival compared to unexposed patients [median survival: 47 months (95% CI: 17-77) vs. 85 months (95% CI: 70-100), unadjusted p = 0.06]. Exposed patients had a higher rate of mortality compared to unexposed patients (HIV/HTLV-I (24/50 [48%]) vs. HIV only (37/100 [37%]), univariable p = 0.2]. HTLV-I exposure was not associated to a higher risk of death in the adjusted analysis: HR: 1.2 (0.4-3.5). AIDS clinical stage and lack of antiretroviral therapy were associated to a higher risk of dying. In conclusions, HTLV-I infection was not associated with a higher risk of death in Peruvian HIV-infected patients. Advanced HIV infection and lack of antiretroviral therapy may explain the excess of mortality in this population.

  16. A 2,300-year-long annually resolved record of the South American summer monsoon from the Peruvian Andes

    PubMed Central

    Bird, Broxton W.; Abbott, Mark B.; Vuille, Mathias; Rodbell, Donald T.; Stansell, Nathan D.; Rosenmeier, Michael F.

    2011-01-01

    Decadal and centennial mean state changes in South American summer monsoon (SASM) precipitation during the last 2,300 years are detailed using an annually resolved authigenic calcite record of precipitation δ18O from a varved lake in the Central Peruvian Andes. This unique sediment record shows that δ18O peaked during the Medieval Climate Anomaly (MCA) from A.D. 900 to 1100, providing evidence that the SASM weakened considerably during this period. Minimum δ18O values occurred during the Little Ice Age (LIA) between A.D. 1400 and 1820, reflecting a prolonged intensification of the SASM that was regionally synchronous. After the LIA, δ18O increased rapidly, particularly during the current warm period (CWP; A.D. 1900 to present), indicating a return to reduced SASM precipitation that was more abrupt and sustained than the onset of the MCA. Diminished SASM precipitation during the MCA and CWP tracks reconstructed Northern Hemisphere and North Atlantic warming and a northward displacement of the Intertropical Convergence Zone (ITCZ) over the Atlantic, and likely the Pacific. Intensified SASM precipitation during the LIA follows reconstructed Northern Hemisphere and North Atlantic cooling, El Niño-like warming in the Pacific, and a southward displacement of the ITCZ over both oceans. These results suggest that SASM mean state changes are sensitive to ITCZ variability as mediated by Western Hemisphere tropical sea surface temperatures, particularly in the Atlantic. Continued Northern Hemisphere and North Atlantic warming may therefore help perpetuate the recent reductions in SASM precipitation that characterize the last 100 years, which would negatively impact Andean water resources. PMID:21555548

  17. Birds of Two Oceans? Trans-Andean and Divergent Migration of Black Skimmers (Rynchops niger cinerascens) from the Peruvian Amazon

    PubMed Central

    Davenport, Lisa C.

    2016-01-01

    Seasonal flooding compels some birds that breed in aquatic habitats in Amazonia to undertake annual migrations, yet we know little about how the complex landscape of the Amazon region is used seasonally by these species. The possibility of trans-Andes migration for Amazonian breeding birds has largely been discounted given the high geographic barrier posed by the Andean Cordillera and the desert habitat along much of the Pacific Coast. Here we demonstrate a trans-Andes route for Black Skimmers (Rynchops niger cinerascens) breeding on the Manu River (in the lowlands of Manu National Park, Perú), as well as divergent movement patterns both regionally and across the continent. Of eight skimmers tracked with satellite telemetry, three provided data on their outbound migrations, with two crossing the high Peruvian Andes to the Pacific. A third traveled over 1800 km to the southeast before transmissions ended in eastern Paraguay. One of the two trans-Andean migrants demonstrated a full round-trip migration back to its tagging location after traveling down the Pacific Coast from latitude 9° South to latitude 37° S, spending the austral summer in the Gulf of Arauco, Chile. This is the first documentation of a trans-Andes migration observed for any bird breeding in lowland Amazonia. To our knowledge, this research also documents the first example of a tropical-breeding waterbird migrating out of the tropics to spend the non-breeding season in the temperate summer, this being the reverse pattern with respect to seasonality for austral migrants in general. PMID:26760301

  18. Conservation Beyond Park Boundaries: The Impact of Buffer Zones on Deforestation and Mining Concessions in the Peruvian Amazon.

    PubMed

    Weisse, Mikaela J; Naughton-Treves, Lisa C

    2016-08-01

    Many researchers have tested whether protected areas save tropical forest, but generally focus on parks and reserves, management units that have internationally recognized standing and clear objectives. Buffer zones have received considerably less attention because of their ambiguous rules and often informal status. Although buffer zones are frequently dismissed as ineffective, they warrant attention given the need for landscape-level approaches to conservation and their prevalence around the world-in Peru, buffer zones cover >10 % of the country. This study examines the effectiveness of buffer zones in the Peruvian Amazon to (a) prevent deforestation and (b) limit the extent of mining concessions. We employ covariate matching to determine the impact of 13 buffer zones on deforestation and mining concessions from 2007 to 2012. Despite variation between sites, these 13 buffer zones have prevented ~320 km(2) of forest loss within their borders during the study period and ~1739 km(2) of mining concessions, an outcome associated with the special approval process for granting formal concessions in these areas. However, a closer look at the buffer zone around the Tambopata National Reserve reveals the difficulties of controlling illegal and informal activities. According to interviews with NGO employees, government officials, and community leaders, enforcement of conservation is limited by uncertain institutional responsibilities, inadequate budgets, and corruption, although formal and community-based efforts to block illicit mining are on the rise. Landscape-level conservation not only requires clear legal protocol for addressing large-scale, formal extractive activities, but there must also be strategies and coordination to combat illegal activities.

  19. River boats contribute to the regional spread of the dengue vector Aedes aegypti in the Peruvian Amazon.

    PubMed

    Guagliardo, Sarah Anne; Morrison, Amy C; Barboza, Jose Luis; Requena, Edwin; Astete, Helvio; Vazquez-Prokopec, Gonzalo; Kitron, Uriel

    2015-04-01

    The dramatic range expansion of the dengue vector Aedes aegypti is associated with various anthropogenic transport activities, but little is known about the underlying mechanisms driving this geographic expansion. We longitudinally characterized infestation of different vehicle types (cars, boats, etc.) to estimate the frequency and intensity of mosquito introductions into novel locations (propagule pressure). Exhaustive adult and immature Ae. aegypti collections were performed on six different vehicle types at five ports and two bus/ taxi departure points in the Amazonian city of Iquitos, Peru during 2013. Aquatic vehicles included 32 large and 33 medium-sized barges, 53 water taxis, and 41 speed boats. Terrestrial vehicles sampled included 40 buses and 30 taxis traveling on the only highway in the region. Ae. aegypti adult infestation rates and immature indices were analyzed by vehicle type, location within vehicles, and sampling date. Large barges (71.9% infested) and medium barges (39.4% infested) accounted for most of the infestations. Notably, buses had an overall infestation rate of 12.5%. On large barges, the greatest number of Ae. aegypti adults were found in October, whereas most immatures were found in February followed by October. The vast majority of larvae (85.9%) and pupae (76.7%) collected in large barges were produced in puddles formed in cargo holds. Because larges barges provide suitable mosquito habitats (due to dark, damp cargo storage spaces and ample oviposition sites), we conclude that they likely serve as significant contributors to mosquitoes' propagule pressure across long distances throughout the Peruvian Amazon. This information can help anticipate vector population mixing and future range expansions of dengue and other viruses transmitted by Ae. aegypti.

  20. Early neurologic abnormalities associated with human T-cell lymphotropic virus type 1 infection in a cohort of Peruvian children

    PubMed Central

    Kendall, Emily A.; González, Elsa; Espinoza, Iván; Tipismana, Martín; Verdonck, Kristien; Clark, Daniel; Vermund, Sten H.; Gotuzzo, Eduardo

    2009-01-01

    Objective Because human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) may occur in some children infected with HTLV-1-infected, we sought to determine the prevalence of neurologic abnormalities and any associations with infective dermatitis in these children. Study design We enrolled 58 children infected with HTLV-1 and 42 uninfected children (ages 3-17) of mothers infected with HTLV-1 in a family study in Lima, Peru. We obtained medical and developmental histories, surveyed current neurologic symptoms, and conducted a standardized neurologic examination without prior knowledge of HTLV-1 status. Results HTLV-1 infection was associated with reported symptoms of lower extremity weakness/fatigue (OR=6.1, CI:0.7–281), lumbar pain (odds ratio [OR] = 1.7, 95% confidence interval [CI]:0.4–8), and paresthesia/dysesthesia (OR=2.6, CI:0.6–15.8). HTLV-1 infection was associated with lower-extremity hyperreflexia (OR=3.1, CI:0.8–14.2), ankle clonus (OR=5.0, CI:1.0–48.3), and extensor plantar reflex (OR undefined; p = 0.2). Among children infected HTLV-1, a history of infective dermatitis was associated with weakness (OR=2.7, CI:0.3–33), lumbar pain (OR=1.3, CI:0.2–8), paresthesia/dysesthesia (OR=2.9, CI:0.5–20), and urinary disturbances (OR=5.7, CI:0.5–290). Conclusions Abnormal neurologic findings were common in Peruvian children infected with HTLV-1, and several findings were co-prevalent with infective dermatitis. Pediatricians should monitor children infected with HTLV-1 for neurologic abnormalities. PMID:19628219

  1. Dealing with AFLP genotyping errors to reveal genetic structure in Plukenetia volubilis (Euphorbiaceae) in the Peruvian Amazon

    PubMed Central

    Vašek, Jakub; Viehmannová, Iva; Ocelák, Martin; Cachique Huansi, Danter; Vejl, Pavel

    2017-01-01

    An analysis of the population structure and genetic diversity for any organism often depends on one or more molecular marker techniques. Nonetheless, these techniques are not absolutely reliable because of various sources of errors arising during the genotyping process. Thus, a complex analysis of genotyping error was carried out with the AFLP method in 169 samples of the oil seed plant Plukenetia volubilis L. from small isolated subpopulations in the Peruvian Amazon. Samples were collected in nine localities from the region of San Martin. Analysis was done in eight datasets with a genotyping error from 0 to 5%. Using eleven primer combinations, 102 to 275 markers were obtained according to the dataset. It was found that it is only possible to obtain the most reliable and robust results through a multiple-level filtering process. Genotyping error and software set up influence both the estimation of population structure and genetic diversity, where in our case population number (K) varied between 2–9 depending on the dataset and statistical method used. Surprisingly, discrepancies in K number were caused more by statistical approaches than by genotyping errors themselves. However, for estimation of genetic diversity, the degree of genotyping error was critical because descriptive parameters (He, FST, PLP 5%) varied substantially (by at least 25%). Due to low gene flow, P. volubilis mostly consists of small isolated subpopulations (ΦPT = 0.252–0.323) with some degree of admixture given by socio-economic connectivity among the sites; a direct link between the genetic and geographic distances was not confirmed. The study illustrates the successful application of AFLP to infer genetic structure in non-model plants. PMID:28910307

  2. Birds of Two Oceans? Trans-Andean and Divergent Migration of Black Skimmers (Rynchops niger cinerascens) from the Peruvian Amazon.

    PubMed

    Davenport, Lisa C; Goodenough, Katharine S; Haugaasen, Torbjørn

    2016-01-01

    Seasonal flooding compels some birds that breed in aquatic habitats in Amazonia to undertake annual migrations, yet we know little about how the complex landscape of the Amazon region is used seasonally by these species. The possibility of trans-Andes migration for Amazonian breeding birds has largely been discounted given the high geographic barrier posed by the Andean Cordillera and the desert habitat along much of the Pacific Coast. Here we demonstrate a trans-Andes route for Black Skimmers (Rynchops niger cinerascens) breeding on the Manu River (in the lowlands of Manu National Park, Perú), as well as divergent movement patterns both regionally and across the continent. Of eight skimmers tracked with satellite telemetry, three provided data on their outbound migrations, with two crossing the high Peruvian Andes to the Pacific. A third traveled over 1800 km to the southeast before transmissions ended in eastern Paraguay. One of the two trans-Andean migrants demonstrated a full round-trip migration back to its tagging location after traveling down the Pacific Coast from latitude 9° South to latitude 37° S, spending the austral summer in the Gulf of Arauco, Chile. This is the first documentation of a trans-Andes migration observed for any bird breeding in lowland Amazonia. To our knowledge, this research also documents the first example of a tropical-breeding waterbird migrating out of the tropics to spend the non-breeding season in the temperate summer, this being the reverse pattern with respect to seasonality for austral migrants in general.

  3. [Serologic response to a DNA recombinant vaccine against hepatitis B in natives of the Peruvian Amazonian jungle].

    PubMed

    Colichón, A; Vildósola, H; Sjogren, M; Cantella, R; Rojas, C

    1990-01-01

    Large areas of the Amazon basin in Brazil, Colombia, Ecuador, and in the nonoriental region of the peruvian jungle have been found to be hyperendemic to Hepatitis B with high prevalence of asymptomatic carriers (11 to 25%) and, in more selected areas, Hepatitis Delta has been also reported. In the present report, we have studied 108 volunteers from six different Jivaroes communities living in a hyperendemic Hepatitis B area. They received 2 doses of DNA recombinant yeast derivated HBV vaccine. All the selected persons were HBsAb negatives, but many (80%) had antibodies to HBc. Following immunization schedule, 80% responded with the formation of HBsAb; a better seroconversion was achieved in those negatives to anticore IgG compared with those having HBcAb. We obtained 90% of seroconversion in spite of the fact that our vaccination schedule was prolonged up to 10 months from the one recommended by the manufacturer. The vaccination schedule 0,4, 14 months, and the schedule 0,4 months, had 76 and 29% of seroconversion, respectively. We want to point out three observations: 1) It is quite possible that many of the Anti-core positives, that did not respond to vaccination were carriers of HBsAg undetectable by the conventional EIA test carried out; 2) The seroconversion rate in these natives was low (up to six months after the vaccination schedule); and 3) Many of the HBcAb were false positives and many of them were recently infected. We conclude: A) It is highly important to assess the anti-HBs hyperendemic areas before attempting vaccinations; B) All persons negative to anti-HBs should be vaccinated in spite to anticore antibodies; C) Areas with difficult access could be vaccinated even until 10 months without affecting good results, and D) DNA recombinant vaccine (ENGERIX B) was well tolerated. No side effects were observed.

  4. Terrigeneous material supply to the Peruvian central continental shelf (Pisco 14° S) during the last 1100 yr: paleoclimatic implications

    NASA Astrophysics Data System (ADS)

    Briceño Zuluaga, F.; Sifeddine, A.; Caquineau, S.; Cardich, J.; Salvatteci, R.; Gutierrez, D.; Ortlieb, L.; Velazco, F.; Boucher, H.; Machado, C.

    2015-07-01

    In the Eastern Pacific, lithogenic input to the ocean is a response of the atmospheric and ocean system variability and their teleconnections over different timescales. Atmospheric (e.g., wind fields, precipitation), hydrological (e.g., fresh water plumes) and oceanic (e.g., currents) conditions determine the transport mode and the amount of lithogenic material transported from the continent to the continental shelf. Here, we present the grain size distribution of a composite record of two laminated sediment cores retrieved in the Peruvian continental shelf, covering the last ~1100 yr at sub-decadal to centennial time-series resolution. We then discuss the paleo-environmental significance and the climatic mechanisms involved. Four grain size modes were identified. Two are linked to aeolian inputs (M3: 53.0 μm and M4: 90.8 μm on average), the third is interpreted as a marker of sediment discharge (M2: 9.4 μm on average), and the last is without an associated origin (M1: ~3 μm). The coarsest components (M3 and M4) dominated during the Medieval Climate Anomaly (MCA) and Current Warm Period (CWP) periods, suggesting that aeolian transport increased as consequence of wind stress intensification. In contrast, M2 displays an opposite behavior, exhibiting an increase in fluvial terrigenous input during the Little Ice Age (LIA), in response to more humid conditions. Comparison with other South American paleoclimate records indicates that the observed changes are driven by interactions between meridional displacement of the Intertropical convergence zone (ITCZ) and of the South Pacific Sub-tropical High (SPSH) at decadal and centennial time scales.

  5. Terrigenous material supply to the Peruvian central continental shelf (Pisco, 14° S) during the last 1000 years: paleoclimatic implications

    NASA Astrophysics Data System (ADS)

    Briceño-Zuluaga, Francisco Javier; Sifeddine, Abdelfettah; Caquineau, Sandrine; Cardich, Jorge; Salvatteci, Renato; Gutierrez, Dimitri; Ortlieb, Luc; Velazco, Federico; Boucher, Hugues; Machado, Carine

    2016-03-01

    In the eastern Pacific, lithogenic input to the ocean responds to variations in the atmospheric and oceanic system and their teleconnections over different timescales. Atmospheric (e.g., wind fields), hydrological (e.g., fresh water plumes) and oceanic (e.g., currents) conditions determine the transport mode and the amount of lithogenic material transported from the continent to the continental shelf. Here, we present the grain size distribution of a composite record of two laminated sediment cores retrieved from the Peruvian continental shelf that record the last ˜ 1000 years at a sub-decadal to centennial time-series resolution. We propose novel grain size indicators of wind intensity and fluvial input that allow reconstructing the oceanic-atmospheric variability modulated by sub-decadal to centennial changes in climatic conditions. Four grain size modes were identified. Two are linked to aeolian inputs (M3: ˜ 54; M4: ˜ 91 µm on average), the third is interpreted as a marker of sediment discharge (M2: ˜ 10 µm on average), and the last is without an associated origin (M1: ˜ 3 µm). The coarsest components (M3 and M4) dominated during the Medieval Climate Anomaly (MCA) and the Current Warm Period (CWP) periods, suggesting that aeolian transport increased as a consequence of surface wind stress intensification. In contrast, M2 displays an opposite behavior, exhibiting an increase in fluvial terrigenous input during the Little Ice Age (LIA) in response to more humid conditions associated with El Niño-like conditions. Comparison with other South American paleoclimate records indicates that the observed changes are driven by interactions between meridional displacement of the Intertropical Convergence Zone (ITCZ), the South Pacific Subtropical High (SPSH) and Walker circulation at decadal and centennial timescales.

  6. Infant iron status affects iron absorption in Peruvian breastfed infants at 2 and 5 mo of age.

    PubMed

    Finkelstein, Julia L; O'Brien, Kimberly O; Abrams, Steven A; Zavaleta, Nelly

    2013-12-01

    Effects of prenatal iron supplementation on maternal postpartum iron status and early infant iron homeostasis remain largely unknown. We examined iron absorption and growth in exclusively breastfed infants in relation to fetal iron exposure and iron status during early infancy. Longitudinal, paired iron-absorption (⁵⁸Fe) studies were conducted in 59 exclusively breastfed Peruvian infants at 2-3 mo of age (2M) and 5-6 mo of age (5M). Infants were born to women who received ≥ 5100 or ≤ 1320 mg supplemental prenatal Fe. Iron status was assessed in mothers and infants at 2M and 5M. Infant iron absorption from breast milk averaged 7.1% and 13.9% at 2M and 5M. Maternal iron status (at 2M) predicted infant iron deficiency (ID) at 5M. Although no infants were iron deficient at 2M, 28.6% of infants had depleted iron stores (ferritin concentration <12 μg/L) by 5M. Infant serum ferritin decreased (P < 0.0001), serum transferrin receptor (sTfR) increased (P < 0.0001), and serum iron decreased from 2M to 5M (P < 0.01). Higher infant sTfR (P < 0.01) and breast-milk copper (P < 0.01) predicted increased iron absorption at 5M. Prenatal iron supplementation had no effects on infant iron status or breast-milk nutrient concentrations at 2M or 5M. However, fetal iron exposure predicted increased infant length at 2M (P < 0.01) and 5M (P < 0.05). Fetal iron exposure affected early infant growth but did not significantly improve iron status or absorption. Young, exclusively breastfed infants upregulated iron absorption when iron stores were depleted at both 2M and 5M.

  7. Act No. 24994 of 19 January 1989. Basic Law on the Rural Development of the Peruvian Amazon Region.

    PubMed

    1989-01-01

    This Act sets forth the government's policy on rural development of the Peruvian Amazon region. Major objectives of the Act include the promotion of new rural settlements in the Amazon region, the promotion of migration from the Andes to the Amazon region, and the stimulation of agriculture, livestock, and forestry activities in the Amazon region. The following are the means that the government will use, among others, to attain these goals: 1) the development of Population Displacement Programmes, which will give individual persons and families economic and logistic support in moving; 2) the establishment of Civic Colonizing Services, temporary mobile units, which will offer settlers health services, education services, technical assistance with respect to agriculture and livestock, and promotional credits; 3) the creation of the Council for Amazon River Transport to coordinate and recommend activities to improve river transport; 4) the granting to settlers of land, free education for their children, medical care, technical training and assistance with respect to agriculture, and a supply of seeds; 5) the exemption of certain investors from payment of income taxes; and 6) the granting of a wide range of incentives for agricultural production. The Act also creates a Council for Planning and Development in the Amazon Region to draw up and approve a Plan for the Development of the Amazon Region. It calls for the rational use of the natural resources of the Amazon Region in the framework of preserving the ecosystem and preventing its ruin and delegates to the regional governments the authority to enter into contracts on the use of forest materials and to undertake reforestation programs. Finally, the Act provides various guarantees for the native population, including guarantees with respect to land and preservation of ethnic and social identity.

  8. Conservation Beyond Park Boundaries: The Impact of Buffer Zones on Deforestation and Mining Concessions in the Peruvian Amazon

    NASA Astrophysics Data System (ADS)

    Weisse, Mikaela J.; Naughton-Treves, Lisa C.

    2016-08-01

    Many researchers have tested whether protected areas save tropical forest, but generally focus on parks and reserves, management units that have internationally recognized standing and clear objectives. Buffer zones have received considerably less attention because of their ambiguous rules and often informal status. Although buffer zones are frequently dismissed as ineffective, they warrant attention given the need for landscape-level approaches to conservation and their prevalence around the world—in Peru, buffer zones cover >10 % of the country. This study examines the effectiveness of buffer zones in the Peruvian Amazon to (a) prevent deforestation and (b) limit the extent of mining concessions. We employ covariate matching to determine the impact of 13 buffer zones on deforestation and mining concessions from 2007 to 2012. Despite variation between sites, these 13 buffer zones have prevented ~320 km2 of forest loss within their borders during the study period and ~1739 km2 of mining concessions, an outcome associated with the special approval process for granting formal concessions in these areas. However, a closer look at the buffer zone around the Tambopata National Reserve reveals the difficulties of controlling illegal and informal activities. According to interviews with NGO employees, government officials, and community leaders, enforcement of conservation is limited by uncertain institutional responsibilities, inadequate budgets, and corruption, although formal and community-based efforts to block illicit mining are on the rise. Landscape-level conservation not only requires clear legal protocol for addressing large-scale, formal extractive activities, but there must also be strategies and coordination to combat illegal activities.

  9. Unstable Malaria Transmission in the Southern Peruvian Amazon and Its Association with Gold Mining, Madre de Dios, 2001-2012.

    PubMed

    Sanchez, Juan F; Carnero, Andres M; Rivera, Esteban; Rosales, Luis A; Baldeviano, G Christian; Asencios, Jorge L; Edgel, Kimberly A; Vinetz, Joseph M; Lescano, Andres G

    2017-02-08

    The reemergence of malaria in the last decade in Madre de Dios, southern Peruvian Amazon basin, was accompanied by ecological, political, and socioeconomic changes related to the proliferation of illegal gold mining. We conducted a secondary analysis of passive malaria surveillance data reported by the health networks in Madre de Dios between 2001 and 2012. We calculated the number of cases of malaria by year, geographic location, intensity of illegal mining activities, and proximity of health facilities to the Peru-Brazil Interoceanic Highway. During 2001-2012, 203,773 febrile cases were identified in Madre de Dios, of which 30,811 (15.1%) were confirmed cases of malaria; all but 10 cases were due to Plasmodium vivax Cases of malaria rose rapidly between 2004 and 2007, reached 4,469 cases in 2005, and then declined after 2010 to pre-2004 levels. Health facilities located in areas of intense illegal gold mining reported 30-fold more cases than those in non-mining areas (ratio = 31.54, 95% confidence interval [CI] = 19.28, 51.60). Finally, health facilities located > 1 km from the Interoceanic Highway reported significantly more cases than health facilities within this distance (ratio = 16.20, 95% CI = 8.25, 31.80). Transmission of malaria in Madre de Dios is unstable, geographically heterogeneous, and strongly associated with illegal gold mining. These findings highlight the importance of spatially oriented interventions to control malaria in Madre de Dios, as well as the need for research on malaria transmission in illegal gold mining camps. © The American Society of Tropical Medicine and Hygiene.

  10. Functional anatomy of the female genital organs of the wild black agouti (Dasyprocta fuliginosa) female in the Peruvian Amazon.

    PubMed

    Mayor, P; Bodmer, R E; Lopez-Bejar, M

    2011-02-01

    This study examined anatomical and histological characteristics of genital organs of 38 black agouti females in the wild in different reproductive stages, collected by rural hunters in the North-eastern Peruvian Amazon. Females in the follicular phase of the estrous cycle had greater antral follicle sizes than other females, the largest antral follicle measuring 2.34mm. Antral follicles in pregnant females and females in luteal phase of the estrous cycle had an average maximum diameter smaller than 1mm. In black agouti females in follicular phase, some antral follicles are selected to continue to growth, reaching a pre-ovulatory diameter of 2mm. Mean ovulation rate was 2.5 follicles and litter size was 2.1 embryos or fetuses per pregnant female, resulting in a rate of ovum mortality of 20.8%. Many follicles from which ovulation did not occur of 1-mm maximum diameter luteinize forming accessory CL. The constituent active luteal tissues of the ovary are functional and accessory CL. Although all females had accessory CL, transformation of follicles into accessory CL occurred especially in pregnant females, resulting in a contribution from 9% to 23% of the total luteal volume as pregnancy advances. The persistence of functional CL throughout pregnancy might reflect the importance for the maintenance of gestation and may be essential for the continuous hormonal production. The duplex uterus of the agouti female is composed by two completely independent uterine horns with correspondent separate cervices opening into the vagina. In pregnant females, most remarkable observed uterine adaptations were induced by the progressive enlargement caused by the normal pregnancy evolution. The wild black agouti showed different vaginal epithelium features in accordance with the reproductive state of the female. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. Endemic pemphigus in the Peruvian Amazon: epidemiology and risk factors for the development of complications during treatment*

    PubMed Central

    Ramos, Willy; Chacon, Gina Rocio; Galarza, Carlos; Gutierrez, Ericson Leonardo; Smith, Maria Eugenia; Ortega-Loayza, Alex Gerardo

    2012-01-01

    BACKGROUND Pemphigus is an autoimmune blistering disease. According to a report, in areas of endemic pemphigus foliaceus (EPF) in Peru there are cases of pemphigus vulgaris with epidemiologic, clinical and histopathologic characteristics similar to those of "endemic pemphigus vulgaris" (EPV) in Brazil. OBJECTIVES To determine the clinical and epidemiologic characteristics of endemic pemphigus and the risk factors of patients for developing complications during treatment. METHODS A study was carried out from July 2003 to March 2008. The study population was 60 patients with EPF and 7 patients with EPV evaluated in hospitals and clinics in the Peruvian Amazon and Lima. A multivariate analysis was carried out using binary logistic regression. RESULTS The average age of EPF patients was 31.4 years; 55% were men; 60% presented the generalized clinical variant. Non-compliance with the treatment was seen in 57.1% of the patients. Thirty-five percent presented complications (e.g. pyodermitis and pyelonephritis) during treatment. The risk factors for developing complications during treatment were non-compliance with the treatment and having the generalized clinical form. In the EPV group, the average age was 21.7 years; 71.4% were men. All patients presented with the mucocutaneous clinical variant and the initial presentation consisted of oral mucosa lesions; 71.4% presented complications during treatment, pyodermitis being the most frequent. CONCLUSIONS Non-compliance with the treatment and the generalized clinical form are risk factors for the development of complications during treatment of patients with EPF. Peru indeed has EPV cases with epidemiologic characteristics similar to EPF. Living in a rural area may represent a risk factor for the development of complications during treatment of patients with EPV. PMID:23197201

  12. Sleep Quality, Sleep Patterns and Consumption of Energy Drinks and Other Caffeinated Beverages among Peruvian College Students

    PubMed Central

    Sanchez, Sixto E.; Martinez, Claudia; Oriol, Raphaelle A.; Yanez, David; Castañeda, Benjamín; Sanchez, Elena; Gelaye, Bizu; Williams, Michelle A.

    2014-01-01

    Objectives To evaluate sleep quality in relation to lifestyle characteristics including consumption of energy drinks and other caffeinated beverages among Peruvian college students. Methods A total of 2,458 college students were invited to complete a self-administered questionnaire that collected information about a variety of behaviors including consumption of energy drinks, caffeinated and alcoholic beverages. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. Logistic regression procedures were used to estimate odds ratios (OR) and 95% confidence intervals (95% CI) for poor sleep quality in relation to lifestyle characteristics. Results A total of 965 males and 1,493 female students were enrolled in the study. 52.0% of males and 58.4% of females experienced poor sleep quality (p=0.002). Females (OR=1.28; 95% CI 1.08–1.51) and those who reported consuming ≥ 3 stimulant beverages per week (OR=1.88; 95% CI 1.42–2.50) had higher odds of poor sleep quality. Students who consumed 1–19 alcoholic beverages monthly (OR=1.90; 95% CI 1.46–2.49) had a higher odds of long sleep latency. Consumption of ≥ 3 stimulant beverages per week was associated with daytime dysfunction due to sleep loss (OR=1.45; 95% CI 1.10–1.90), short sleep duration (OR= 1.49; 95% CI 1.14–1.94), and use of sleep medication (OR= 2.10; 95% CI 1.35–3.28). Conclusions Consumption of energy drinks, other caffeinated beverages and alcoholic beverages are risk factors of poor sleep quality. Increased awareness of these associations should promote interventions to improve students’ lifestyle habits, including consumption of alcoholic and caffeinated beverages, and overall health. PMID:25243056

  13. Glacier changes and climate trends derived from multiple sources in the data scarce Cordillera Vilcanota region, southern Peruvian Andes

    NASA Astrophysics Data System (ADS)

    Salzmann, N.; Huggel, C.; Rohrer, M.; Silverio, W.; Mark, B. G.; Burns, P.; Portocarrero, C.

    2013-01-01

    The role of glaciers as temporal water reservoirs is particularly pronounced in the (outer) tropics because of the very distinct wet/dry seasons. Rapid glacier retreat caused by climatic changes is thus a major concern, and decision makers demand urgently for regional/local glacier evolution trends, ice mass estimates and runoff assessments. However, in remote mountain areas, spatial and temporal data coverage is typically very scarce and this is further complicated by a high spatial and temporal variability in regions with complex topography. Here, we present an approach on how to deal with these constraints. For the Cordillera Vilcanota (southern Peruvian Andes), which is the second largest glacierized cordillera in Peru (after the Cordillera Blanca) and also comprises the Quelccaya Ice Cap, we assimilate a comprehensive multi-decadal collection of available glacier and climate data from multiple sources (satellite images, meteorological station data and climate reanalysis), and analyze them for respective changes in glacier area and volume and related trends in air temperature, precipitation and in a more general manner for specific humidity. While we found only marginal glacier changes between 1962 and 1985, there has been a massive ice loss since 1985 (about 30% of area and about 45% of volume). These high numbers corroborate studies from other glacierized cordilleras in Peru. The climate data show overall a moderate increase in air temperature, mostly weak and not significant trends for precipitation sums and probably cannot in full explain the observed substantial ice loss. Therefore, the likely increase of specific humidity in the upper troposphere, where the glaciers are located, is further discussed and we conclude that it played a major role in the observed massive ice loss of the Cordillera Vilcanota over the past decades.

  14. Socioeconomic status and chronic child malnutrition: Wealth and maternal education matte