Science.gov

Sample records for 4c1 chair conformation

  1. Pseudorotational landscape of seven-membered rings: the most stable chair and twist-boat conformers of ε-caprolactone.

    PubMed

    Jahn, Michaela K; Dewald, David A; Vallejo-López, Montserrat; Cocinero, Emilio J; Lesarri, Alberto; Zou, Wenli; Cremer, Dieter; Grabow, Jens-Uwe

    2014-10-20

    The conformational landscape and ring-puckering properties of ε-caprolactone have been analyzed by using microwave spectroscopy and quantum chemical calculations. Two conformers were detected in a supersonic jet expansion, the most stable form being a chair containing the ester group in its rectangular flap. This conformation benefits from reduced CH2 bond eclipsing and angle strain, while π-electron delocalization in the ester group is increased. The derived effective structure of the chair form satisfactorily agrees with the calculated near-equilibrium structure. A twist-boat conformer was also identified (9.4 kJ mol(-1) higher in energy at CCSD(T)/aug-cc-pVTZ level), and was located in the boat-twist-boat pseudorotation cycle of the seven-membered ring. Three other low-energy conformers were investigated and characterized in terms of the four puckering coordinates of the seven-membered ring. Potential interconversions in the four-dimensional conformation space are also discussed. PMID:25196306

  2. The six-membered ring chair conformation of butane-1,3-diol in the gas phase

    NASA Astrophysics Data System (ADS)

    Caminati, Walther; Corbelli, Giorgio

    1982-02-01

    Only one conformer of butane-1,3-diol is detectable by conventional microwave spectroscopy. Analysis of the CH 2OHCH 2CHOHMe and CH 2ODCH 2CHODMe isotopic species has allowed the determination of this conformation as a hydrogen-chelated six-membered ring in a distorted chair configuration. The hydrogen atom in position 1 is the proton donor; the methyl group is trans to the C 1-C 2 bond and the hydroxyl hydrogen in position 3 is trans to the C 2-C 3 bond.

  3. Reversible chair ↔ skew conformational interconversion of 1,3,2-dioxaphosphorinane ring in the solid state.

    PubMed

    Řlepokura, Katarzyna Anna

    2016-02-01

    β-NH4[(MeO)2cDHAP] (where cDHAP is cyclic dihydroxyacetone phosphate) has been investigated by X-ray crystallography in the temperature range 350-100 K. Three reversible single-crystal-to-single-crystal phase transitions have been examined and four phases (high-, room-, medium- and low-temperature phase, HTP, RTP, MTP and LTP, respectively) have been structurally determined: HTP (at 350 K, P2(1)/a, Z = 24), RTP (290 K, P1, Z = 12), MTP (205 K, P2(1)/a, Z = 4) and LTP (100 K, P1, Z = 24). Various puckering modes of the 1,3,2-dioxaphosphorinane ring of the organic cyclic phosphate anion have been revealed in the crystal: chair and skew. The chair ↔ skew ring flipping, which has been shown to take place during the phase transitions, results in various populations of skew and chair conformers in different phases. The flexibility in the coordination geometry of ammonium cations is considered to assist in the conformational flexibility of the dioxaphosphorinane ring. PMID:26830803

  4. DFT studies of the conformation and relative energies of alpha-maltotetraose (DP-4): An amylose fragment at atomic resolution

    Technology Transfer Automated Retrieval System (TEKTRAN)

    DFT optimization studies of more than one hundred conformations of a-maltotetraose have been carried out at the B3LYP/6-311++G** level of theory. The DP-4 fragments of predominately 4C1 chair residues include tightly bent forms, helix, band-flips, kinks, boat, and some 1C4 conformers. The three do...

  5. A conformational model of per-O-acetyl-cyclomaltoheptaose (-beta-cyclodextrin) in solution: detection of partial inversion of glucopyranose units by NMR spectroscopy.

    PubMed

    Uccello-Barretta, Gloria; Sicoli, Giuseppe; Balzano, Federica; Salvadori, Piero

    2003-05-01

    The stereochemical features of per-O-acetyl-cyclomaltoheptaose (-beta-cyclodextrin) have been investigated in solution by NMR spectroscopy, and the deviation of functionalised glucopyranose rings from 4C(1) chairs to skew-type conformations has been detected. PMID:12706976

  6. Folding chair

    DOEpatents

    Cornell, Howell N.

    1985-08-20

    A foldable chair of the lawn chair type has ground-engaging front and rear legs, attached to and carrying a back frame and seat frame, the back frame and seat frame being pivotally attached to a spreader rod which extends beyond the back and seat frames to bear against one of the leg members when the chair is unfolded. A contact pad mounted on the extending portion of the spreader rod is formed as an externally-contoured bushing fit over the spreader rod and adapted to engage the leg member to restrict side-to-side movement of the spreader rod, with respect to the leg member, when the chair is unfolded.

  7. First Chair.

    ERIC Educational Resources Information Center

    Stewart, Donald C.

    1993-01-01

    A high school sophomore exceptionally talented on the violin is enraged and indignant when a less accomplished senior is given first chair in the school orchestra. After reacting rudely to the orchestra director and the principal, the girl discusses the situation with her supportive parents and resolves the problem. (JDD)

  8. Ergonomic Chairs

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Findings published in the NASA Anthropometric Source Book by Johnson Space Center helped BodyBilt, Inc. to fashion controlled comfort chairs that lessen the harmful effects of gravity on seated workers. Crew members living aboard NASA's Skylab noted that in space the human posture differs from the normal posture caused by the tug of one gravity. There has been an alarming increase in back pain and muscle fatigue in workers, along with a dramatic escalation in repetitive stress injuries. BodyBilt's ergonomically-correct line of office chairs are targeted for the average worker that sits for prolonged periods, be it in the classroom or boardroom. Their roster of national clients lists such organizations as IBM, Microsoft, Texas Instruments, Hewlett-Packard, Eastman-Kodak, Boeing, Motorola, and Walt Disney Studios.

  9. Computational mutagenesis reveals the role of active-site tyrosine in stabilising a boat conformation for the substrate: QM/MM molecular dynamics studies of wild-type and mutant xylanases.

    PubMed

    Soliman, Mahmoud E S; Ruggiero, Giuseppe D; Pernía, J Javier Ruiz; Greig, Ian R; Williams, Ian H

    2009-02-01

    Molecular dynamics simulations have been performed for non-covalent complexes of phenyl beta-xylobioside with the retaining endo-beta-1,4-xylanase from B. circulans (BCX) and its Tyr69Phe mutant using a hybrid QM/MM methodology. A trajectory initiated for the wild-type enzyme-substrate complex with the proximal xylose ring bound at the -1 subsite (adjacent to the scissile glycosidic bond) in the (4)C(1) chair conformation shows spontaneous transformation to the (2,5)B boat conformation, and potential of mean force calculations indicate that the boat is approximately 30 kJ mol(-1) lower in free energy than the chair. Analogous simulations for the mutant lacking one oxygen atom confirm the key role of Tyr69 in stabilizing the boat in preference to the (4)C(1) chair conformation, with a relative free energy difference of about 20 kJ mol(-1), by donating a hydrogen bond to the endocyclic oxygen of the proximal xylose ring. QM/MM MD simulations for phenyl beta-xyloside in water, with and without a propionate/propionic acid pair to mimic the catalytic glutamate/glutamic acid pair of the enzyme, show the (4)C(1) chair to be stable, although a hydrogen bond between the OH group at C2 of xylose and the propionate moiety seems to provide some stabilization for the (2,5)B conformation. PMID:19156310

  10. Radiation Pattern of Chair Armed Microstrip Antenna

    NASA Astrophysics Data System (ADS)

    Mishra, Rabindra Kishore; Sahu, Kumar Satyabrat

    2016-07-01

    This work analyzes planar antenna conformable to chair arm shaped surfaces for WLAN application. Closed form expressions for its radiation pattern are developed and validated using measurements on prototype and commercial EM code at 2.4 GHz.

  11. Uncovering the Relationship between Sulphation Patterns and Conformation of Iduronic Acid in Heparan Sulphate

    NASA Astrophysics Data System (ADS)

    Hsieh, Po-Hung; Thieker, David F.; Guerrini, Marco; Woods, Robert J.; Liu, Jian

    2016-07-01

    The L-iduronic acid (IdoA) residue is a critically important structural component in heparan sulphate polysaccharide for the biological functions. The pyranose ring of IdoA is present in 1C4-chair, 2SO-skew boat, and less frequently, in 4C1-chair conformations. Here, we analyzed the conformation of IdoA residue in eight hexasaccharides by NMR. The data demonstrate a correlation between the conformation of IdoA and sulphations in the surrounding saccharide residues. For the 2-O-sulpho IdoA residue, a high degree of sulphation on neighboring residues drives ring dynamics towards the 2SO-skew boat conformer. In contrast, the nonsulphated IdoA residue is pushed towards the 1C4-chair conformer when the neighboring residues are highly sulphated. Our data suggest that the conformation of IdoA is regulated by the sulphation pattern of nearby saccharides that is genetically controlled by the heparan sulphate biosynthetic pathway.

  12. Uncovering the Relationship between Sulphation Patterns and Conformation of Iduronic Acid in Heparan Sulphate

    PubMed Central

    Hsieh, Po-Hung; Thieker, David F.; Guerrini, Marco; Woods, Robert J.; Liu, Jian

    2016-01-01

    The L-iduronic acid (IdoA) residue is a critically important structural component in heparan sulphate polysaccharide for the biological functions. The pyranose ring of IdoA is present in 1C4-chair, 2SO-skew boat, and less frequently, in 4C1-chair conformations. Here, we analyzed the conformation of IdoA residue in eight hexasaccharides by NMR. The data demonstrate a correlation between the conformation of IdoA and sulphations in the surrounding saccharide residues. For the 2-O-sulpho IdoA residue, a high degree of sulphation on neighboring residues drives ring dynamics towards the 2SO-skew boat conformer. In contrast, the nonsulphated IdoA residue is pushed towards the 1C4-chair conformer when the neighboring residues are highly sulphated. Our data suggest that the conformation of IdoA is regulated by the sulphation pattern of nearby saccharides that is genetically controlled by the heparan sulphate biosynthetic pathway. PMID:27412370

  13. A wireless ballistocardiographic chair.

    PubMed

    Junnila, Sakari; Akhbardeh, Alireza; Barna, Laurentiu C; Defee, Irek; Varri, Alpo

    2006-01-01

    This paper presents a wireless ballistocardiographic chair developed for the Proactive Health Monitoring project in the Institute of Signal Processing. EMFi sensors are used for BCG measurement and IEEE 802.15.4 RF link for radio communication between the chair and a PC. The chair measures two BCG signals from the seat and the backrest and a rough ECG signal from the armrests of the chair. The R-spike of the ECG signal can be used as a synchronisation point to extract individual BCG cardiac cycles. Also, two developed methods for extracting BCG cycles without using a reference ECG signal are presented and compared. PMID:17946348

  14. An Ergonomic Chair?

    MedlinePlus

    ... Ergonomic Chair? Food Safety Industrial Hygiene Integrated Pest Management OSHA 300A Summaries Public Access Defibrillation Program Drinking Water Safety Workplace Injury and Illness Trend Analysis Surveys ...

  15. The Supportive Chair.

    ERIC Educational Resources Information Center

    Rosbottom, Ronald C.

    1987-01-01

    Recommendations for chairs of college-level foreign language departments include: being supportive of the department; communicating fully and openly with faculty and staff; promoting grantsmanship; and encouraging staff and faculty. Recommendations for deans working with chairs and department heads include: consulting frequently and communicating…

  16. About Department Chairs.

    ERIC Educational Resources Information Center

    Bennett, John B.

    1989-01-01

    Department chairs occupy what is arguably one of the most important administrative spots in a higher education institution. As a group, they set the academic tone of the institution and greatly facilitate or hinder the accomplishment of its mission. The various types of department chairs are described: hopeful, survivors, transient, and…

  17. 4 CFR 27.2 - The Chair, Vice Chair.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false The Chair, Vice Chair. 27.2 Section 27.2 Accounts GOVERNMENT ACCOUNTABILITY OFFICE GENERAL PROCEDURES GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL APPEALS BOARD; ORGANIZATION § 27.2 The Chair, Vice Chair. The members of the Board shall select from among its membership...

  18. Stress Reducing Chair

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Flogiston Chair incorporates NASA human factors in spacecraft design technology as well as information from NASA's Anthropometric Source Book. Designed by Brian V. Park, it provides a close approximation of the natural position a body assumes in weightless space. Its principal markets are information workers, designers, software developers, data processors, etc. It assists in maintaining concentration, is useful for relaxation and reality ventures. The chair may be fixed, rockable, or suspended from the ceiling.

  19. Indoxyl Sulfate Down-Regulates SLCO4C1 Transporter through Up-Regulation of GATA3

    PubMed Central

    Suzuki, Takehiro; Takeuchi, Yoichi; Mishima, Eikan; Yamamoto, Yasuaki; Ishida, Ayako; Sugawara, Daiki; Jinno, Daisuke; Shima, Hisato; Toyohara, Takafumi; Suzuki, Chitose; Souma, Tomokazu; Moriguchi, Takashi; Tomioka, Yoshihisa; Ito, Sadayoshi; Abe, Takaaki

    2013-01-01

    The accumulated uremic toxins inhibit the expression of various renal transporters and this inhibition may further reduce renal function and subsequently cause the accumulation of uremic toxins. However, the precise mechanism of the nephrotoxicity of uremic toxins on renal transport has been poorly understood. Here we report that indoxyl sulfate, one of the potent uremic toxins, directly suppresses the renal-specific organic anion transporter SLCO4C1 expression through a transcription factor GATA3. The promoter region of SLCO4C1 gene has several GATA motifs, and indoxyl sulfate up-regulated GATA3 mRNA and subsequently down-regulated SLCO4C1 mRNA. Overexpression of GATA3 significantly reduced SLCO4C1 expression, and silencing of GATA3 increased SLCO4C1 expression vice versa. Administration of indoxyl sulfate in rats reduced renal expression of slco4c1 and under this condition, plasma level of guanidinosuccinate, one of the preferable substrates of slco4c1, was significantly increased without changing plasma creatinine. Furthermore, in 5/6 nephrectomized rats, treatment with oral adsorbent AST-120 significantly decreased plasma indoxyl sulfate level and conversely increased the expression of slco4c1, following the reduction of plasma level of guanidinosuccinate. These data suggest that the removal of indoxyl sulfate and blocking its signal pathway may help to restore the SLCO4C1-mediated renal excretion of uremic toxins in CKD. PMID:23874392

  20. A double diastereoselective Michael-type addition as an entry to conformationally restricted tn antigen mimics.

    PubMed

    Aydillo, Carlos; Navo, Claudio D; Busto, Jesús H; Corzana, Francisco; Zurbano, María M; Avenoza, Alberto; Peregrina, Jesús M

    2013-11-01

    A totally stereocontrolled C-Michael addition of serine-equivalent C-nucleophiles to tri-O-benzyl-2-nitro-d-galactal was used as the key step to synthesize several pyrano[3,2-b]pyrrole structures. These scaffolds could be regarded as conformationally restricted Tn antigen mimics, as we have demonstrated by biological assays. The pyranose rings retain their (4)C1 chair conformation, as shown by molecular modeling and NMR spectroscopy. The expected bioactivity was established by a competition-tailored enzyme-linked lectin assay using both soybean and Vicia villosa agglutinins as model lectins. The facile described synthetic route and the strategic combination of computational and experimental techniques to reveal conformational features and bioactivity demonstrate the prepared glycomimics to be promising candidates for further exploitation of this scaffold to give glycans for lectin blocking and vaccination. PMID:24083620

  1. Conformational changes of 1-4-glucopyranosyl residues of a sulfated C-C linked hexasaccharide.

    PubMed

    Coletti, Alessia; Elli, Stefano; Macchi, Eleonora; Galzerano, Patrizia; Zamani, Leila; Guerrini, Marco; Torri, Giangiacomo; Vismara, Elena

    2014-05-01

    This work describes the structure of a fully sulfated maltotriose alpha-beta C-C linked dimer, where a central glycosidic bond was substituted by a non natural, hydrolase-resistant C-C bond. Such compound shows anti-metastatic properties being an inhibitor of the heparanase enzymatic activity and of P-selectin-mediated cell-cell interactions. NMR spectroscopy was applied to investigate the structure and conformational properties of this C-C linked hexasaccharide. The presence of sulfate substituents and the internal C-C bond drives the two internal rings in an unusual (1)C(4) chair conformation, while the external rings linked by glycosidic bonds retain the typical (4)C(1) conformation. The NMR results were confirmed by molecular mechanics calculations using structure corresponding di- and tetrasaccharides as models. PMID:24680506

  2. Conformational changes of 1-4-glucopyranosyl residues of a sulfated C—C linked hexasaccharide

    PubMed Central

    Coletti, Alessia; Elli, Stefano; Macchi, Eleonora; Galzerano, Patrizia; Zamani, Leila; Guerrini, Marco; Torri, Giangiacomo; Vismara, Elena

    2014-01-01

    This work describes the structure of a fully sulfated maltotriose alpha–beta C—C linked dimer, where a central glycosidic bond was substituted by a non natural, hydrolase-resistant C—C bond. Such compound shows anti-metastatic properties being an inhibitor of the heparanase enzymatic activity and of P-selectin-mediated cell–cell interactions. NMR spectroscopy was applied to investigate the structure and conformational properties of this C—C linked hexasaccharide. The presence of sulfate substituents and the internal C—C bond drives the two internal rings in an unusual 1C4 chair conformation, while the external rings linked by glycosidic bonds retain the typical 4C1 conformation. The NMR results were confirmed by molecular mechanics calculations using structure corresponding di- and tetrasaccharides as models. PMID:24680506

  3. Solubility of alkali metal halides in the ionic liquid [C4C1im][OTf].

    PubMed

    Kuzmina, O; Bordes, E; Schmauck, J; Hunt, P A; Hallett, J P; Welton, T

    2016-06-28

    The solubilities of the metal halides LiF, LiCl, LiBr, LiI, NaF, NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbCl, CsCl, CsI, were measured at temperatures ranging from 298.15 to 378.15 K in the ionic liquid 1-butyl-3-methylimidazolium trifluoromethanesulfonate ([C4C1im][OTf]). Li(+), Na(+) and K(+) salts with anions matching the ionic liquid have also been investigated to determine how well these cations dissolve in [C4C1im][OTf]. This study compares the influence of metal cation and halide anion on the solubility of salts within this ionic liquid. The highest solubility found was for iodide salts, and the lowest solubility for the three fluoride salts. There is no outstanding difference in the solubility of salts with matching anions in comparison to halide salts. The experimental data were correlated employing several phase equilibria models, including ideal mixtures, van't Hoff, the λh (Buchowski) equation, the modified Apelblat equation, and the non-random two-liquid model (NRTL). It was found that the van't Hoff model gave the best correlation results. On the basis of the experimental data the thermodynamic dissolution parameters (ΔH, ΔS, and ΔG) were determined for the studied systems together with computed gas phase metathesis parameters. Dissolution depends on the energy difference between enthalpies of fusion and dissolution of the solute salt. This demonstrates that overcoming the lattice energy of the solid matrix is the key to the solubility of inorganic salts in ionic liquids. PMID:27264676

  4. Chair-ish.

    ERIC Educational Resources Information Center

    Greenman, Geri

    2000-01-01

    Presents an art assignment that helps students progress from color theory and the color wheel to understanding watercolor techniques. Explains that students apply their knowledge of watercolor techniques by using three of ten techniques to create different views of a chair in the Cubist style. (CMK)

  5. Chairing a Small Department.

    ERIC Educational Resources Information Center

    Bowker, Lee H.; Lynch, David M.

    Ten management problems for chairs of small departments in small colleges are discussed, along with problem-solving strategies for these administrators. Serious disagreements within a small and intimate department may create a country club culture in which differences are smoothed over and the personal idiosyncrasies of individual members are…

  6. Resources Available to Department Chairs.

    ERIC Educational Resources Information Center

    Lynch, David M.; Bowker, Lee H.

    Resources available to department chairs from the following sources are described: the department's discipline; the national higher education community; the local institution; and the chair's own skills, background, roles, and structural placement within the organization. The use of these resources to deal with common problems faced by chairs is…

  7. 12 CFR 225.109 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false âServicesâ under section 4(c)(1) of Bank Holding Company Act. 225.109 Section 225.109 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding...

  8. 12 CFR 225.104 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 3 2013-01-01 2013-01-01 false âServicesâ under section 4(c)(1) of Bank... (REGULATION Y) Regulations Financial Holding Companies Interpretations § 225.104 “Services” under section 4(c... payroll, life insurance and budget loan installment account. (2) In the second case, Corporation Y,...

  9. 12 CFR 225.104 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false âServicesâ under section 4(c)(1) of Bank... GOVERNORS OF THE FEDERAL RESERVE SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION Y... and budget loan installment account. (2) In the second case, Corporation Y, a nonbanking subsidiary...

  10. 12 CFR 225.109 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 3 2013-01-01 2013-01-01 false âServicesâ under section 4(c)(1) of Bank Holding Company Act. 225.109 Section 225.109 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF... (REGULATION Y) Regulations Financial Holding Companies Interpretations § 225.109 “Services” under section...

  11. 12 CFR 225.109 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 3 2012-01-01 2012-01-01 false âServicesâ under section 4(c)(1) of Bank Holding Company Act. 225.109 Section 225.109 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION...

  12. 12 CFR 225.109 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false âServicesâ under section 4(c)(1) of Bank Holding Company Act. 225.109 Section 225.109 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding...

  13. 12 CFR 225.104 - “Services” under section 4(c)(1) of Bank Holding Company Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Holding Company Act. 225.104 Section 225.104 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF... Holding Company Act. (a) Section 4(c)(1) of the Bank Holding Company Act, among other things, exempts from the nonbanking divestment requirements of section 4(a) of the Act shares of a company engaged...

  14. A chair on alternatives?

    PubMed

    Spielmann, Horst

    2002-01-01

    An overview is given on the legal framework in Europe for the use of experimental animals set by EU (European Union) Directive 86/609/EEC and on the activities of EU member states to implement this directive in the field of regulatory testing in animals. The significant decrease in the number of experimental animals in Germany during the past decade is described with particular reference to the recent increase that is due to transgenic animal models. From the regulatory and the animal welfare perspective the international harmonisation of test guidelines and the mutual acceptance of data are the way forward for chemical safety testing. The recent White Paper of the EU Commission for the future chemicals policy calls for an immediate increase in the number of validated in vitro toxicity tests to be accepted for regulatory purposes in the EU. In addition, deficits of properly educating young scientists in Germany in conducting animal experiments and implementing the 3-Rs concept of Russel and Burch are described. It is therefore, quite urgent to establish new chairs on animals and alternatives at universities in Europe. They should focus on both education young students of the biomedical sciences in the humane use of laboratory animals according to the 3-Rs concept and on developing new toxicity tests to be validated for regulatory purposes under the new EU chemicals policy by the established validation centres in Europe. PMID:12098012

  15. Conformational Analysis of a Dermatan Sulfate-Derived Tetrasaccharide by NMR, Molecular Modeling, and Residual Dipolar Couplings

    PubMed Central

    Silipo, Alba; Zhang, Zhenqing; Cañada, F. Javier; Molinaro, Antonio

    2014-01-01

    The solution conformation behavior of a dermatan-derived tetrasaccharide—ΔHexA-(1→3)-GalNAc4S-β-(1→4)-IdoA-α-(1→3)-red-GalNAc4S (S is a sulfate group)—has been explored by means of NMR spectroscopy, especially by NOE-based conformational analysis. The tetrasaccharide was present as four species, two of which are chemically different in the anomeric orientation of the reducing 2-deoxy-2-acetamido-galactose (red-GalNAc) residue, while the other two are the result of different conformations of the iduronic acid (IdoA) unit. The two α–-interconverting anomers were present in a 0.6:1 ratio. Ring conformations have been defined by analysis of 3JH,H coupling constants and interresidual NOE contacts. Both 2-deoxy-2-acetamido-galactose (GalNAc) residues were found in the 4C1 chair conformation, the unsaturated uronic acid (Δ-Hex A) adopts a strongly predominant half-chair 1H2 conformation, while the IdoA residue exists either in the 1C4 chair or in the 2S0 skewed boat geometries, in a 4:1 ratio. There is a moderate flexibility of Φ and Ψ torsions as suggested by nuclear Overhauser effects (NOEs), molecular modeling (MM), and molecular dynamics (MD) studies. This was further investigated by residual dipolar couplings (RDCs). One-bond C–H RDCs (1DC,H) and long-range H–H (3DH,H) RDCs were measured for the tetrasaccharide in a phage solution and interpreted in combination with restrained MD simulation. The RDC-derived data substantially confirmed the validity of the conformer distribution resulting from the NOE-derived simulations, but allowed an improved definition of the conformational behavior of the oligosaccharides in solution. In summary, the data show a moderate flexibility of the four tetrasaccharide species at the central glycosidic linkage. Differences in the shapes of species with the IdoA in skew and in chair conformations and in the distribution of the sulfate groups have also been highlighted. PMID:18072186

  16. [How Charcot got his chair].

    PubMed

    Gelfand, T

    1994-01-01

    Charcot's career, as is well-known, reached a summit with his acquisition of the Faculty clinical chair of diseases of the nervous system inaugurated in 1882. Based upon previously untapped archival materials at the Charcot Library and the National Archives, this paper explores four questions: I. Was "Charcot's chair" really the first specialized chair for neurology?; 2. Was it founded specifically for Charcot?; 3. What role did the Faculty of Medicine play and did it offer any opposition?; 4. How important was the creation of the chair for the flourishing of the Salpêtrière school. Evidence is presented to show that Charcot considered a specialized chair in nervous diseases a high priority for his career and his school. Sometime around 1880, convinced of the importance of this project, he began to assemble arguments in its behalf from French and foreign sources, particularly from his German colleagues, Westphal and Erb. He learned that there were no precedents, not even in Berlin. Charcot's carefully prepared manuscript memoir presented a strong case for the "necessity" of the chair based on the recent progress and theoretical as well as practical importance of his subject. He described psychiatry, which already had a Faculty clinical chair, as but a "small part" of neuropathology and rejected the idea of combining the two disciplines. Although the project encountered opposition from several Faculty colleagues, who claimed that it was a personal favor for Charcot, powerful support from political allies such as Gambetta and Ferry ensured government funding. In fact, government action in behalf of the creation of the chair for Charcot preceded and surprised the medical Faculty. This paper shows the extent to which Charcot's own initiatives and arguments set the agenda and defined the role he envisaged for the new foundation at the center of the clinical research and teaching centre emerging under his direction at the Salpêtrière. PMID:11640483

  17. Conformation of some sparteine N-16 oxides revisited

    NASA Astrophysics Data System (ADS)

    Thiel, Jacek; Boczoń, Władysław; Fiedorow, Piotr; Jasiewicz, Beata; Knychała, Małgorzata

    2002-12-01

    Sparteine N-16 oxides were thought to occur in all chair conformations with cis fusion between their C and D rings. NMR spectral analysis made possible indication of the chair- chair- boat- chair form with cis fussion of C, D rings for sparteine, 2-phenyl- and 2-methylsparteine N-16 oxides. Molecular energy found by means of DFT, Hartree-Fock, AM1, PM3 methods supported this new shape of bisquinolizidine skeleton.

  18. A Tale of Three Chairs.

    ERIC Educational Resources Information Center

    Carnes, Jim

    1998-01-01

    Drawing from the work of Henry David Thoreau, urges us to see the relationship between the individual and his/her community. Thoreau had three chairs in his cabin: one for solitude, one for friendship, and one for society. Like Thoreau, school leaders could make a career of exploring the tension between public and private imperatives. (MLH)

  19. 21 CFR 886.1140 - Ophthalmic chair.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ophthalmic chair. 886.1140 Section 886.1140 Food... DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1140 Ophthalmic chair. (a) Identification. An ophthalmic chair is an AC-powered or manual device with adjustable positioning in which a patient is to...

  20. Robotic chair at steep and narrow stairways

    NASA Astrophysics Data System (ADS)

    Imazato, Masahiro; Yamaguchi, Masahiro; Moromugi, Shunji; Ishimatsu, Takakazu

    2007-12-01

    A robotic chair is developed to support mobility of elderly and disabled people living in the house where steep and narrow stairways are installed. In order to deal with such mobility problem the developed robotic chair has a compact original configuration. The robotic chair vertically moves by actuation of electric cylinders and horizontally moves by push-pull operation given by a care-giver. In order to navigate safely every action of the chair is checked by the operator. Up-and-down motions of the robotic chair on the stairway are executed through combinations of motor and cylinder actuations. Performance of the robotic chair was evaluated through two kinds of experiments. The excellent ability of the robotic chair could be confirmed through these experiments.

  1. The Department Chair: Between a Rock and a Hard Place.

    ERIC Educational Resources Information Center

    Wilson, Vicki

    This paper provides a review of the literature on the roles and responsibilities of the academic departmental chair in colleges and universities. Carroll and Gmelch (1992) found four orientations in a factor analysis of department chair duties: leader chairs, scholar chairs, faculty developer chairs, and manager chairs. Creswell and Brown (1992)…

  2. Chair like NiAu6: Clusters assemblies and CO oxidation study by ab initio methods

    NASA Astrophysics Data System (ADS)

    Nigam, Sandeep; Sahoo, Suman Kalyan; Sarkar, Pranab; Majumder, Chiranjib

    2013-10-01

    Based on the first-principles approach, this Letter reports that the ground state geometry of the Ni@Au6 cluster forms chair-like conformation, which is distinctly different than the Pd@Au6 and Pt@Au6 clusters, where hexagonal planar structure is favored over non-planar isomers. The higher stability of the chair-like conformation has been verified through various complementary basis sets and methodologies. Further investigations were carried out to show the stability of a cluster assembled material (CAM) based on these small clusters and the CO oxidation reaction was carried out to establish their uses as an industrial catalyst.

  3. 21 CFR 890.3100 - Mechanical chair.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Mechanical chair. 890.3100 Section 890.3100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3100 Mechanical chair....

  4. 21 CFR 890.3100 - Mechanical chair.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Mechanical chair. 890.3100 Section 890.3100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3100 Mechanical chair....

  5. 21 CFR 890.3100 - Mechanical chair.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Mechanical chair. 890.3100 Section 890.3100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3100 Mechanical chair....

  6. 21 CFR 890.3100 - Mechanical chair.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Mechanical chair. 890.3100 Section 890.3100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3100 Mechanical chair....

  7. Chairs of Graduate Departments: A Structural Profile.

    ERIC Educational Resources Information Center

    Van Valey, Thomas L.; Tiemann, Kathleen

    1990-01-01

    Analyzes all U. S. sociology departments listed in the American Sociological Association Guide to Graduate Departments of Sociology from 1969 to 1985 with respect to the backgrounds of chairs as well as selected structural characteristics of their departments. Finds that chairs who are male and who hold the rank of full professor continue to be…

  8. 21 CFR 890.3100 - Mechanical chair.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mechanical chair. 890.3100 Section 890.3100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3100 Mechanical chair....

  9. Enhancing the Effectiveness of Department Chairs

    ERIC Educational Resources Information Center

    Lumpkin, Angela

    2004-01-01

    The department chair is one of the most challenging positions in higher education. Advancing one's department can occur by attending to the parameters that highly successful organizations have implemented. In addition to outlining the challenges of serving as a department chair, this article describes four requirements for dealing with, and…

  10. Secondary School Science Department Chairs Leading Change

    ERIC Educational Resources Information Center

    Gaubatz, Julie A.

    2012-01-01

    Secondary school department chairs are content area specialists in their schools and are responsible for providing students with the most appropriate curricula. However, most secondary school department chairs have limited authority to institute change unilaterally (Gmelch, 1993; Hannay & Erb, 1999). To explore how these educational leaders…

  11. Who Will Be Your Next Board Chair?

    ERIC Educational Resources Information Center

    Wilson, E. B.

    2004-01-01

    This article suggests that trustees give the same high level of thoughtful consideration to selecting the board chair as they give to filling the presidency. More than the routine filling of a vacancy, the process for naming the board's next chair amounts to the selection of a governance team. The board's most important responsibility is not only…

  12. Depletion of Intracellular Ca2+ Stores Stimulates the Translocation of Vanilloid Transient Receptor Potential 4-C1 Heteromeric Channels to the Plasma Membrane

    PubMed Central

    Ma, Xin; Cao, Jingyuan; Luo, Jianhong; Nilius, Bernd; Huang, Yu; Ambudkar, Indu S.; Yao, Xiaoqiang

    2016-01-01

    Objective To examine the effect of Ca2+ store depletion on the translocation of vanilloid transient receptor potential (TRPV) 4-C1 heteromeric channels to the plasma membrane. Methods and Results Vesicular trafficking is a key mechanism for controlling the surface expression of TRP channels in the plasma membrane, where they perform their function. TRP channels in vivo are often composed of heteromeric subunits. Experiments using total internal fluorescence reflection microscopy and biotin surface labeling show that Ca2+ store depletion enhanced TRPV4-C1 translocation into the plasma membrane in human embryonic kidney 293 cells that were coexpressed with TRPV4 and canonical transient receptor potential 1 (TRPC1). Fluorescent Ca2+ measurement and patch clamp studies demonstrated that Ca2+ store depletion enhanced 4α-PDD–stimulated Ca2+ influx and cation current. The translocation required stromal interacting molecule 1 (STIM1). TRPV4-C1 heteromeric channels were more favorably translocated to the plasma membrane than TRPC1 or TRPV4 homomeric channels. Similar results were obtained in native vascular endothelial cells. Conclusion Ca2+ store depletion stimulates the insertion of TRPV4-C1 heteromeric channels into the plasma membrane, resulting in an augmented Ca2+ influx in response to flow in the human embryonic kidney cell overexpression system and native endothelial cells. PMID:20705915

  13. Conformations and Conformational Processes of Hexahydrobenzazocines by NMR and DFT Studies.

    PubMed

    Musielak, Bogdan; Holak, Tad A; Rys, Barbara

    2015-09-18

    Conformational processes that occur in hexahydrobenzazocines have been studied with the (1)H and (13)C dynamic nuclear magnetic resonance (DNMR) spectroscopy. The coalescence effects are assigned to two different conformational processes: the ring-inversion of the ground-state conformations and the interconversion between two different conformers. The barriers for these processes are in the range of 42-52 and 42-43 kJ mol(-1), respectively. Molecular modeling on the density functional theory (DFT) level and the gauge invariant atomic orbitals (GIAO)-DFT calculations of isotropic shieldings and coupling constants for the set of low-energy conformations were compared with the experimental NMR data. The ground-state of all compounds in solution is the boat-chair (BC) conformation. The BC form adopts two different conformations because the nitrogen atom can be in the boat or chair parts of the BC structure. These two conformers are engaged in the interconversion process. PMID:26317238

  14. 2011 AGU Workshop for Heads & Chairs

    NASA Astrophysics Data System (ADS)

    Fox, Lydia K.; Asher, Pranoti

    2012-02-01

    The AGU Board of Heads & Chairs of Departments of Earth and Space Sciences (H&C) held its annual workshop on Sunday, 4 December, at the 2011 Fall Meeting. The workshop included presentations on successful strategies for various aspects of the role of department head or chair, as well as time for small group discussions and networking among the group. There were nearly 60 participants, representing all stages of the chair life cycle, from seasoned veterans to those about to assume the role. Participants also represented a variety of institution types, both public and private, from 2-year colleges to research universities.

  15. Toward Consistent Terminology for Cyclohexane Conformers in Introductory Organic Chemistry

    ERIC Educational Resources Information Center

    Nelson, Donna J.; Brammer, Christopher N.

    2011-01-01

    Recommended changes in use of cyclohexane conformers and their nomenclature will remedy inconsistencies in cyclohexane conformers and their nomenclature that exist across currently used organic chemistry textbooks. These inconsistencies prompted this logical analysis and the resulting recommendations. Recommended conformer names are "chair",…

  16. Transcriptional regulation of organic anion transporting polypeptide SLCO4C1 as a new therapeutic modality to prevent chronic kidney disease.

    PubMed

    Suzuki, Takehiro; Toyohara, Takafumi; Akiyama, Yasutoshi; Takeuchi, Yoichi; Mishima, Eikan; Suzuki, Chitose; Ito, Sadayoshi; Soga, Tomoyoshi; Abe, Takaaki

    2011-09-01

    Uremic toxins accumulate in patients with chronic kidney diseases (CKDs) and cause further progression of renal damage and cardiovascular diseases. Recently, it was reported that some of the organic anion transporting polypeptides (OATPs) and the organic anion transporters (OATs) are involved in the renal elimination of uremic toxins. SLCO4C1 is the only OATP expressed at the basolateral side of proximal tubular cells in human kidney, and it mediates the excretion of uremic toxins. The overexpression of human SLCO4C1 in rat kidney promotes the renal excretion of uremic toxins and reduces hypertension, cardiomegaly, and renal inflammation in renal failure. Statins induce SLCO4C1 expression thorough transcriptional factor Aryl hydrocarbon receptor through binding of the xenobiotic responsive element at its promoter region. The administration of statin in a rat renal failure model facilitated the elimination of uremic toxins and mitigated organ damage. In addition, metabolomic analysis of rat renal failure models and patients with CKD by capillary electrophoresis-mass spectrometry is a useful method for identifying new uremic solutes and explores surrogate biomarkers for detecting the progression of early stage CKD. PMID:21656517

  17. Disaccharide conformational maps: adiabaticity in analogs with variable ring shapes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Relaxed MM3 potential energy surfaces (conformational maps) were calculated for analogs of the three trehaloses, maltose, cellobiose and galabiose based on 2-methyltetrahydropyran. Starting structures included not only 4C1 (sugar nomenclature) geometries, but also combinations with 1C4 conformers, a...

  18. The Disintegrating Chair: Professors in Britain Today.

    ERIC Educational Resources Information Center

    Moodie, Graeme

    1986-01-01

    Changes in the status of the British "chair" or professorship in the twentieth century are examined, with focus on the types of changes, the reasons for them, and the administrative, educational, and intellectual results. (MSE)

  19. Chair Talk: Resources to Maximize Administrative Efforts

    NASA Astrophysics Data System (ADS)

    MacDonald, H.; Chan, M. A.; Bierly, E. W.; Manduca, C. A.; Ormand, C. J.

    2009-12-01

    Earth science department chairs are generally scientists who have little/no formal administrative training. The common rotation of faculty members in three-six year cycles distributes the heavy leadership responsibilities but involves little preparation beforehand to deal with budgets, fundraising, personnel issues, confrontations, and crises. The amount of information exchange and support upon exit and handoff to the next chair is variable. Resources for chairs include workshops, meetings (ranging from annual meetings of geoscience chairs to monthly meetings of small groups of chairs from various disciplines on a campus), discussions, and online resources. These resources, some of which we designed in the past several years, provide information and support for chairs, help them share best practices, and reduce time spent “reinventing the wheel”. Most of these resources involve groups of chairs in our discipline who meet together. The AGU Board of Heads and Chairs of Earth and Space Science Departments offers annual one-day workshops at the Fall AGU meeting. The specific topics vary from year to year; they have included goals and roles of heads and chairs, fundraising and Advisory Boards, student recruitment, interdisciplinarity, dual-career couples, and undergraduate research. The workshop provides ample opportunities for open discussion. Annual one-two day meetings of groups of geoscience department chairs (e.g., research universities in a particular region) provide an opportunity for chairs to share specific data about their departments (e.g., salaries, graduate student stipends, information about facilities) and discuss strategies. At the College of William and Mary, a small group of chairs meets monthly throughout the year; each session includes time for open discussion as well as a more structured discussion on a particular topic (e.g., merit review, development and fundraising, mentoring early career faculty and the tenure process, leadership styles

  20. Secondary school science department chairs leading change

    NASA Astrophysics Data System (ADS)

    Gaubatz, Julie A.

    Secondary school department chairs are content area specialists in their schools and are responsible for providing students with the most appropriate curricula. However, most secondary school department chairs have limited authority to institute change unilaterally (Gmelch, 1993; Hannay & Erb, 1999). To explore how these educational leaders navigate the change process within their departments, this study examined the change stories of six secondary school science department chairs who had led change attempts. In total, these department chairs shared six stories of successful change attempts and four unsuccessful change attempts. The topics of leadership and change were accessed through department chair interviews, document analysis, and a leadership inventory. Department chair leadership was analyzed with Blake and McCanse's (1991) Leadership Grid, and further explored using Yukl, Gordon, and Taber's (2002) detailed characterization of this grid. The change processes described in these department chair stories were analyzed using the frameworks provided by Ely's (1990) conditions of change, and Havelock and Zlotolow (1995) CREATER change stages model. In general, the findings of this study support Havelock and Zlotolow's CREATER model, as well as Ely's conditions of change, with dissatisfaction with the status quo emerging as the essential condition for successful change. This study connects these change process frameworks to specific leadership strategies and behaviors, and uses these connections to illuminate differences between successful and unsuccessful instances of change. These findings, along with other unanticipated findings emerging from department chair stories of change, such as the adverse influence of contentious resistors and the importance of team construction, add both to the literature on change and leadership and to the crucial point where these concepts intersect.

  1. The Cost of Academic Leadership: Department Chair Stress.

    ERIC Educational Resources Information Center

    Gmelch, Walter H.; Burns, John S.

    Findings from a study that examined stresses associated with the role of the university department chair are presented in this paper. The focuses are on career paths, transitions to the chair position, commitment to administration, role orientation, and strains of chairing. A survey of 808 department chairs in 101 research and doctoral-granting…

  2. Skylab experiment M131: Rotating little chair

    NASA Technical Reports Server (NTRS)

    Evans, J. S.; Zitterkopf, D. L.; Konigsberg, R. L.; Blackburn, C. M.

    1977-01-01

    Physiological considerations suggest that the response of the vestibular system can be substantially modified during weightlessness and that such modifications affect susceptibility to motion sickness and to judgment of spatial localization. Evaluation of such effects requires measurement of responses to rotational accelerations before, during, and after exposure to conditions of prolonged zero-gravity. For this purpose, a precisely controlled rotating chair was designed, constructed, tested, and installed in the Skylab Orbital Workshop. The chair was used in three test modes to measure changes in the vestibular (balance) organs of the astronauts.

  3. A carpet-weaver's chair based on anthropometric data.

    PubMed

    Mahmoudi, Nader; Bazrafshan, Majid

    2013-01-01

    Ergonomic design of chairs has been well studied by ergonomists. Chair design based on anthropometric data analysis is recommended. Weavers in carpet-weaving workshops use chairs with backrests and armrests. An anthropometric survey was carried out among weavers in Tabriz, Iran, to design a flexible chair and to improve its comfort on the basis of design dimensions. This study focused on the design dimensions of a chair for weavers and its recommended dimensions. The developed chair needs to be tested for its effects on weavers' posture and comfort. PMID:24321633

  4. The future-oriented department chair.

    PubMed

    Grigsby, R Kevin; Hefner, David S; Souba, Wiley W; Kirch, Darrell G

    2004-06-01

    The authors describe the current dilemma facing academic health centers (AHCs) as they recruit department chairs. In the past, leaders at AHCs predominantly were concerned with fulfilling the esteemed tripartite missions of patient care, research, and education. Today, their time and energy are occupied by a different set of tasks that have a distinct business orientation, including winning contracts, enhancing revenue, reducing costs, recruiting and managing a diverse workforce, and dealing with consumer satisfaction and marketing. New visions and strategies must be developed--requiring different dimensions of leadership. The authors offer concrete recommendations for recruiting, retaining, and sustaining department chairs, and argue that a deliberative, thoughtful process of engaging chair candidates should begin by focusing on the candidates' values as a first priority. Candidates who most clearly share organizational values should then be engaged in an iterative process of developing a shared vision, resulting in a letter of agreement that explicitly states the mutual expectations and commitments of both the organization and the candidate. Once department chairs are in place, ongoing development through leadership training, mentoring, and other investments help to retain and sustain them. PMID:15165977

  5. The Department Chair: A Descriptive Study.

    ERIC Educational Resources Information Center

    Seedorf, Rita G.; Gmelch, Walter H.

    Information is presented on a study which investigated the managerial role of the academic department chair and compared it to a study of traditional managers. The study compared management activities to determine whether or not there was a difference between academic management and management outside of the university setting. It made use of the…

  6. Perceptions of Leadership Styles of Department Chairs

    ERIC Educational Resources Information Center

    Whitsett, Glee

    2007-01-01

    Much has been written about leadership in business management, but very little research has been done on leadership in academic departments. Department chairs have the authority to make most departmental decisions, but rarely does formal training exist for this position. Therefore, there is a need to study how the leadership styles among…

  7. CCCC Chair's Address: Representing Ourselves, 2008

    ERIC Educational Resources Information Center

    Glenn, Cheryl

    2008-01-01

    This article presents the text of the author's address at the fifty-ninth annual convention of the Conference on College Composition and Communication (CCCC) in March 2008. In her address, the author picks up strands of previous Chairs' addresses and weaves them through the fabric of her remarks. What she hopes will give sheen to the fabric is her…

  8. 21 CFR 892.1820 - Pneumoencephalographic chair.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Pneumoencephalographic chair. 892.1820 Section 892.1820 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... pneumoencephalography (x-ray imaging of the brain). (b) Classification. Class II....

  9. 21 CFR 892.1820 - Pneumoencephalographic chair.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Pneumoencephalographic chair. 892.1820 Section 892.1820 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... pneumoencephalography (x-ray imaging of the brain). (b) Classification. Class II....

  10. 21 CFR 892.1820 - Pneumoencephalographic chair.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Pneumoencephalographic chair. 892.1820 Section 892.1820 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... pneumoencephalography (x-ray imaging of the brain). (b) Classification. Class II....

  11. 21 CFR 892.1820 - Pneumoencephalographic chair.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Pneumoencephalographic chair. 892.1820 Section 892.1820 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... pneumoencephalography (x-ray imaging of the brain). (b) Classification. Class II....

  12. 21 CFR 892.1820 - Pneumoencephalographic chair.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Pneumoencephalographic chair. 892.1820 Section 892.1820 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... pneumoencephalography (x-ray imaging of the brain). (b) Classification. Class II....

  13. The Real Work of Department Chair.

    ERIC Educational Resources Information Center

    Bowman, Richard F., Jr.

    2002-01-01

    Argues that secondary and post secondary academic department chairs are both managers and leaders whose real work is to manage conversational inquiry that engages others in creating possibilities, breakthroughs, and a sustainable future for their common enterprise. Describes leadership capabilities demanded by this work; well-honed communication…

  14. Experimental investigation of chair type, row spacing, occupants, and carpet on theatre chair absorption.

    PubMed

    Choi, Young-Ji; Bradley, John S; Jeong, Dae-Up

    2015-01-01

    This paper examines how the individual variations of chair type, row spacing, as well as the presence of occupants and carpet, combine to influence the absorption characteristics of theater chairs as a function of sample perimeter-to-area (P/A) ratios. Scale models were used to measure the interactive effects of the four test variables on the chair absorption characteristics, avoiding the practical difficulties of full scale measurements. All of the test variables led to effects that could lead to important changes to auditorium acoustics conditions. At mid and higher frequencies, the various effects can usually be explained as due to, more or less, porous absorbing material. In the 125 and 250 Hz octave bands, the major changes were attributed to resonant absorbing mechanisms. The results indicate that for accurate predictions of the effective absorption of the chairs in an auditorium, one should use the P/A method and reverberation chamber tests of the chair absorption coefficients to predict the absorption coefficients of each block of chairs and use these results as input in a room acoustics computer model of the auditorium. The application of these results to auditorium acoustics design is described, more approximate approaches are considered, and relations to existing methods are discussed. PMID:25618043

  15. Review of the medical and legal literature on restraint chairs.

    PubMed

    Castillo, Edward M; Coyne, Christopher J; Chan, Theodore C; Hall, Christine A; Vilke, Gary M

    2015-07-01

    Use of restraint chairs by law enforcement for violent individuals has generated controversy and a source of litigation because of reported injuries and deaths of restrained subjects. The purpose of this study is to review the available medical and legal literature and to allow the development of evidence-based, best practice recommendations to inform the further development of restraint chair policies. This is a structured literature review of four databases, two medical and two legal. The medical review focus was on the restraint chair with additional review of materials regarding other restraint methods and options. The legal review focused on litigation cases involving the restraint chair. The review of the medical literature revealed 21 peer-reviewed studies investigating the physiological or psychological effects of using a restraint chair on humans or primates. Of these studies, 20 were performed on primates. The single human study revealed no clinically significant effects from the restraint chair on test subjects. The legal literature review revealed very few cases where the restraint chair was either a major or minor focus. The overall issues relating to the restraint chair cases involved deviations from set protocols and rarely involved issues with the chair itself. The available medical literature reveals that the restraint chair poses little to no medical risk. Additionally, when used appropriately, the restraint chair alone carries little legal liability. With proper monitoring and adherence to set protocols, the restraint chair is a safe and appropriate device for use in restraining violent individuals. PMID:26048505

  16. Science Instructional Leadership: The Role of the Department Chair

    ERIC Educational Resources Information Center

    Peacock, Jeremy S.

    2014-01-01

    With science teachers facing comprehensive curriculum reform that will shape science education for decades to come, high school department chairs represent a critical resource for instructional leadership and teacher support. While the historical literature on the department chair indicates that chairs are in prime positions to provide…

  17. 21 CFR 880.6140 - Medical chair and table.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Medical chair and table. 880.6140 Section 880.6140...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6140 Medical chair and table. (a) Identification. A medical chair or table is a...

  18. 21 CFR 872.6250 - Dental chair and accessories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Dental chair and accessories. 872.6250 Section 872...) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6250 Dental chair and accessories. (a) Identification. A dental chair and accessories is a device, usually AC-powered, in which a patient sits....

  19. 21 CFR 872.6250 - Dental chair and accessories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Dental chair and accessories. 872.6250 Section 872...) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6250 Dental chair and accessories. (a) Identification. A dental chair and accessories is a device, usually AC-powered, in which a patient sits....

  20. 21 CFR 872.6250 - Dental chair and accessories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Dental chair and accessories. 872.6250 Section 872...) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6250 Dental chair and accessories. (a) Identification. A dental chair and accessories is a device, usually AC-powered, in which a patient sits....

  1. 21 CFR 872.6250 - Dental chair and accessories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Dental chair and accessories. 872.6250 Section 872...) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6250 Dental chair and accessories. (a) Identification. A dental chair and accessories is a device, usually AC-powered, in which a patient sits....

  2. 21 CFR 872.6250 - Dental chair and accessories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Dental chair and accessories. 872.6250 Section 872...) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6250 Dental chair and accessories. (a) Identification. A dental chair and accessories is a device, usually AC-powered, in which a patient sits....

  3. 21 CFR 880.6140 - Medical chair and table.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Medical chair and table. 880.6140 Section 880.6140...) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use Miscellaneous Devices § 880.6140 Medical chair and table. (a) Identification. A medical chair or table is a...

  4. Probabilistic model-based methodology for the conformational study of cyclic systems: application to copper complexes double-bridged by phosphate and related ligands.

    PubMed

    Kessler, M; Pérez, J; Bueso, M C; García, L; Pérez, E; Serrano, J L; Carrascosa, R

    2007-12-01

    A methodology for the conformational study of cyclic systems through the statistical analysis of torsion angles is presented. It relies on a combination of different methods based on a probabilistic model which takes into account the topological symmetry of the structures. This methodology is applied to copper complexes double-bridged by phosphate and related ligands. Structures from the Cambridge Structural Database (CSD) are analyzed and the chair, boat-chair and boat conformations are identified as the most frequent conformations. The output of the methodology also provides information about distortions from the ideal conformations, the most frequent being: chair <--> twist-chair, chair <--> twist-boat-chair and boat <--> twist-boat. Molecular mechanics calculations identify these distortions as energetically accessible pathways. PMID:18004042

  5. Samuel P. Massie Chair of Excellence Program

    SciTech Connect

    Johnson, James H

    2014-12-15

    Abstract In 1994 the Department of Energy established the DOE Chair of Excellence Professorship in Environmental Disciplines Program. In 2004, the Massie Chair of Excellence Professor at Howard University transitioned from Dr. Edward Martin to Dr. James H. Johnson, Jr. At the time of his appointment Dr. Johnson served as professor of civil engineering and Dean of the College of Engineering, Architecture and Computer Sciences. Program activities under Dr. Johnson were in the following areas: • Increase the institution’s capacity to conduct scientific research and technical investigations at the cutting-edge. • Promote interactions, collaborations and partnerships between the private sector, Federal agencies, majority research institutes and other HBCUs. • Assist other HBCUs in reaching parity in engineering and related fields. • Mentor young investigators and be a role model for students.

  6. Space Grant Research Launches Rehabilitation Chair

    NASA Technical Reports Server (NTRS)

    2015-01-01

    Working with funding from the National Space Grant College and Fellowship Program-which was implemented by NASA Headquarters to fund research, education, and public service projects-a biomedical engineering student created a vibration-based system that could combat bone loss from prolonged trips to space. A rehabilitation chair incorporating the technology is now sold by Sheboygan, Wisconsin-based VibeTech Inc. and is helping people recover more quickly from injuries and surgery.

  7. Polarity, viscosity, and ionic conductivity of liquid mixtures containing [C4C1im][Ntf2] and a molecular component.

    PubMed

    Lopes, J N Canongia; Gomes, Margarida F Costa; Husson, Pascale; Pádua, Agílio A H; Rebelo, Luis Paulo N; Sarraute, Sabine; Tariq, Mohammad

    2011-05-19

    In this study, we have focused on binary mixtures composed of 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)-imide, [C(4)C(1)im][Ntf(2)], and a selection of six molecular components (acetonitrile, dichloromethane, methanol, 1-butanol, t-butanol, and water) varying in polarity, size, and isomerism. Two Kamlet-Taft parameters, the polarizability π* and the hydrogen bond acceptor β coefficient were determined by spectroscopic measurements. In most cases, the solvent power (dipolarity/polarizability) of the ionic liquid is only slightly modified by the presence of the molecular component unless large quantities of this component are present. The viscosity and electrical conductivity of these mixtures were measured as a function of composition and the relationship between these two properties were studied through Walden plot curves. The viscosity of the ionic liquid dramatically decreases with the addition of the molecular component. This decrease is not directly related to the volumetric properties of each mixture or its interactions. The conductivity presents a maximum as a function of the composition and, except for the case of water, the conductivity maxima decrease for more viscous systems. The Walden plots indicate enhanced ionic association as the ionic liquid gets more diluted, a situation that is the inverse of that usually found for conventional electrolyte solutions. PMID:21517046

  8. Conformational analysis of primary ethylene ozonide by gradient and multiconfigurational scf calculations

    NASA Astrophysics Data System (ADS)

    Ruoff, Peter; Almlöf, Jan; Sæbø, Svem

    1980-06-01

    Four conformers of ethylene primary ozonide have been studied by ab initio gradient and MC SCF calculations, using gaussian-type basis functions. The MC SCF results indicate that the conformers are not as close in energy as suggested from single-determinant SCF calculations. The oxygen-oxygen and carbon-oxygen half-chair structures are much lower in energy than the carbon-carbon half-chair.

  9. The Conformational Behaviour of Glucosamine

    NASA Astrophysics Data System (ADS)

    Peña, Isabel; Kolesniková, Lucie; Cabezas, Carlos; Bermúdez, Celina; Berdakin, Matías; Simao, Alcides; Alonso, José L.

    2014-06-01

    A laser ablation method has been successfully used to vaporize the bioactive amino monosaccharide D-glucosamine. Three cyclic α-4C1 pyranose forms have been identified using a combination of CP-FTMW and LA-MB-FTMW spectroscopy. Stereoelectronic hyperconjugative factors, like those associated with anomeric or gauche effects, as well as the cooperative OH\\cdotsO, OH\\cdotsN and NH\\cdotsO chains, extended along the entire molecule, are the main factors driving the conformational behavior. All observed conformers exhibit a counter-clockwise arrangement (cc) of the network of intramolecular hydrogen bonds. The results are compared with those recently obtained for D-glucose. J. L. Alonso, M. A. Lozoya, I. Peña, J. C. López, C. Cabezas, S. Mata, S. Blanco, Chem. Sci. 2014, 5, 515.

  10. Body Mass Measurement Chair - Experiment M172

    NASA Technical Reports Server (NTRS)

    1970-01-01

    Skylab's Body Mass Measurement chair, the facility of the Body Mass Measurement experiment (M172), is shown here in this 1970 photograph. The M172 experiment determined the body mass of each crew member and observed changes in body masses during flight. Knowledge of exact body mass variations throughout the flight in significantly aided in the correlation of other medical data obtained during the flight. Mass measurements under zero-gravity conditions were achieved by the application of Newton's second law (force equals mass times acceleration). The Marshall Space Flight Center had program management responsibility for the development of Skylab hardware and experiments.

  11. Embrace the challenge: advice for current and prospective department chairs.

    PubMed

    Sheldon, George F

    2013-07-01

    In this issue, Kastor discusses the challenges and responsibilities of a contemporary chair of medicine as described in interviews of 44 chairs. As a chair of surgery at the University of North Carolina at Chapel Hill for 17 years, the author of this commentary uses his own experiences to reflect on how the insights presented in Kastor's commentary can apply to department chairs in other specialties. Elements from Kastor's commentary, as well as additional observations from the author's tenure, may be sources of advice to future chairs of any department. The author concludes that, despite a changing health care environment and other significant leadership challenges, being a department chair is a rewarding job with many opportunities to pursue worthwhile objectives. PMID:23799438

  12. Ceramide 1-phosphate enhances calcium entry through voltage-operated calcium channels by a protein kinase C-dependent mechanism in GH4C1 rat pituitary cells.

    PubMed Central

    Törnquist, Kid; Blom, Tomas; Shariatmadari, Ramin; Pasternack, Michael

    2004-01-01

    Sphingomyelin derivatives modulate a multitude of cellular processes, including the regulation of [Ca2+]i (the intracellular free calcium concentration). Previous studies have shown that these metabolites often inhibit calcium entry through VOCCs (voltage-operated calcium channels). In the present study, we show that, in pituitary GH4C1 cells, C1P (C2-ceramide 1-phosphate) enhances calcium entry in a dose-dependent manner. The phospholipase C inhibitor U73122 attenuated the response. C1P invoked a small, but significant, increase in the formation of inositol phosphates. Pre-treatment of the cells with pertussis toxin was without an effect on the C1P-evoked increase in [Ca2+]i. The effect of C1P was critically dependent on extracellular calcium, since no increase in [Ca2+]i was observed when cells in a calcium-free buffer were stimulated with C1P. Furthermore, if the cells were retreated with 300 nM of the VOCC inhibitor nimodipine, the effect of C1P was almost totally abolished. In addition, ceramide C8-1-phosphate evoked an increase in [Ca2+]i, but the onset of the response was slow compared with that of C1P. In cells treated with 1 mM thapsigargin for 15 min, C1P still evoked an increase in [Ca2+]i. In patch-clamp experiments in the whole-cell mode, C1P enhanced calcium entry through the VOCCs compared with vehicle-treated cells. Dialysis of the cells with C1P did not enhance the calcium current. On-cell patch-clamp experiments showed an enhanced probability of the VOCCs being open (P(open)) in the presence of C1P. Inhibition of PKC (protein kinase C) with GF109203X and down-regulation of PKC with PMA attenuated the C1P-evoked increase in [Ca2+]i. Furthermore, down-regulation of PKC abolished the effect of C1P on P(open). This is the first report showing that a sphingomyelin derivative enhances calcium entry through VOCCs. PMID:15018614

  13. Chair of a department of medicine: now a different job.

    PubMed

    Kastor, John A

    2013-07-01

    The job of chair of a department of medicine, once seen as the apex in the career of an academic internist, has lost much of its allure, in part because of increasing administrative and financial obligations that require more of the time and effort of chairs than formerly. This is the impression the author gathered from interviewing 44 current and former chairs, deans, division chiefs, and hospital directors.He was told that chairs have lost some of their independence as departments have become increasingly dependent on the support of the executives at their university hospitals who, as the source of funds and facilities, can even specify which clinical services the chairs may develop. Conflict over the assignment of resources between dean and hospital CEO, which one interviewee stated can produce "incredible tensions," can complicate efforts of chairs to build clinical and research strength within their departments according to their own preferences. The growing administrative and financial duties of the job have forced some chairs to decrease their dedication to the classic responsibilities of teaching medical students and house officers.Recruiting outstanding leaders for departments of medicine challenges search committees and deans more than in the past because many suitable candidates do not choose to be considered and prefer to lead institutes, centers, or specialty divisions. The author suggests, however, that schools-by providing chairs with adequate administrative support and authority-can structure the job to improve its attractiveness and allow chairs more time to engage in traditional academic pursuits. PMID:23799437

  14. A Qualitative Study of Faculty Members' Views of Women Chairs

    PubMed Central

    Isaac, Carol; Griffin, Lindsay

    2010-01-01

    Abstract Background Concurrent with the evolving role of the department chair in academic medicine is the entry of women physicians into chair positions. Because implicit biases that stereotypically masculine behaviors are required for effective leadership remain strong, examining faculty members' perceptions of their chair's leadership in medical school departments with women chairs can provide insight into the views of women leaders in academic medicine and the complex ways in which gender may impact these chairs' leadership style and actions. Methods We conducted semistructured interviews with 13 male and 15 female faculty members representing all faculty tracks in three clinical departments chaired by women. Inductive, qualitative analysis of the subsequent text allowed themes to emerge across interviews. Results Four themes emerged regarding departmental leadership. One dealt with the leadership of the previous chair. The other three described the current chair's characteristics (tough, direct, and transparent), her use of communal actions to help support and mentor her faculty, and her ability to build power through consensus. Because all three chairs were early in their tenure, a wait and see attitude was frequently expressed. Faculty generally viewed having a woman chair as an indication of positive change, with potential individual and institutional advantages. Conclusions This exploratory study suggests that the culture of academic medicine has moved beyond questioning women physicians' competence to lead once they are in top organizational leadership positions. The findings are also consonant with experimental research indicating that women leaders are most successful when they pair stereotypic male (agentic) behaviors with stereotypic female (communal) behaviors. All three chairs exhibited features of a transformational leadership style and characteristics deemed essential for effective leadership in academic medicine. PMID:20156081

  15. Evaluating Department Chair and Student Leadership in Higher Education

    ERIC Educational Resources Information Center

    Thurston, Linda P.; Middendorf, B. Jan

    2009-01-01

    In higher education, assessment of leadership capacities and performance of department chairs and students allows stakeholders to evaluate individuals and programs. To that end, this article describes the Individual Development and Educational Assessment (IDEA) Feedback for Department Chairs system, a psychometrically sound instrument developed…

  16. The Hot Seat: Profiling the Marketing Department Chair

    ERIC Educational Resources Information Center

    Aggarwal, Praveen; Rochford, Linda; Vaidyanathan, Rajiv

    2009-01-01

    The chair of the marketing department serves a critical role in balancing the needs of the university with those of the faculty. Because most department chairs are drawn from the faculty in their departments, the administrative role they take on conflicts with their desire to maintain their academic roles as teacher and researcher. Although there…

  17. The Strategic Value of Succession Planning for Department Chairs.

    PubMed

    Rayburn, William; Grigsby, Kevin; Brubaker, Linda

    2016-04-01

    Most faculty who aspire to be department chairs are unaware of succession processes at their institution. This Commentary highlights the importance of succession planning, emphasizing the general need for transparency. Succession planning provides institutional leaders the opportunity to optimize, renew, and revitalize their organization by ensuring successful leadership transitions. In contrast to leadership pathways in the military, corporate business, and hospital administration, planned succession of medical school department chairs has received little attention. Different approaches to succession planning are essential for emergency and planned transitions. Emergency succession plans should be in place at all times, regularly revisited, and modified as needed. Department chairs should begin considering their planned succession between one and five years after their initial appointment. The succession discussion between a chair and medical school dean requires cautious, thoughtful, and open discussions. Intradepartmental annual faculty performance evaluations permit the chair to mentor potential successors in acquiring future-oriented, institution-based leadership qualities necessary to be considered for a future department chair position. If health and time permit, the successful chair should remain in his or her current position until a successor is named or, preferably, is in place. Appointment of an interim chair as part of succession planning can be useful for on-the-job training of an internal candidate, yet awkwardness might ensue if there is more than one internal candidate.Succession development offers the great advantage of maintaining smooth organizational performance while optimizing talent management and exploring opportunities for transitioning individuals into leadership roles. PMID:26556290

  18. Promoting Excellent Teaching: The Chair as Academic Leader.

    ERIC Educational Resources Information Center

    Lamb, Bill

    Community college department chairs have many diverse responsibilities. One role which needs to be given more emphasis is that of "promoting excellent teaching." The three conditions which must be present for a department chair to begin promoting excellent teaching are open, honest, and positive communication; the ability to provide immediate…

  19. Effective Communication for Academic Chairs. SUNY Series in Speech Communication.

    ERIC Educational Resources Information Center

    Hickson, Mark, III, Ed.; Stacks, Don W.

    This book presents 11 contributed papers which examine communication aspects of the department chair position in academia. It is noted that most academic department chairs are not trained in management skills, including communication strategies. After an introductory chapter by Christopher H. Spicer and Ann Q. Staton, the following papers are…

  20. The Future Competencies of Department Chairs: A Human Resources Perspective

    ERIC Educational Resources Information Center

    Jones, Faye R.

    2011-01-01

    This exploratory study of department chairs, deans, and faculty at extensive research public universities in Florida resulted in the identification of 85 future competencies of department chairs using a human resources perspective. Results include a discussion of the top 20 most important competencies and the top 20 competencies anticipated to be…

  1. Turnover of First-Time Chairs in Departments of Psychiatry

    ERIC Educational Resources Information Center

    Buckley, Peter F.; Rayburn, William F.

    2011-01-01

    Objective: The authors examine the tenure of first-time Chairs in academic departments of psychiatry in order to stimulate discussion on extant workforce and leadership issues. Method: Data on tenure of Chairs in psychiatry and other nonsurgical specialties were derived from the longitudinal database of the Association of American Medical Colleges…

  2. Electromyography comparison of normal chair-desk system and assistant chair-desk system on fatigue.

    PubMed

    Kwon, Moon-Seok; Lee, Sang-Ho; Cho, Ik-Rae; Won, Yu-Mi; Han, Mi-Kyung; Jung, Kon-Nym; Lee, Jae-Hee; Chin, Ji-Hyoung; Rho, Jae-Hun; Kim, Ju-Yeon; Yang, Jae-Bong; No, Jae-Kui; Park, Tae-Geun; Lee, Taek-Kyun; Park, Hyo-Joo; Lee, Sam-Jun; Yoo, Kyoung-Seok; Kang, Suh-Jung; Kwon, Se-Jeong; Shin, Mi-Ae; Kim, Hu-Nyun; Kahn, Hyung-Sik; Kim, Min-Jung; Kim, Tae-Young

    2015-10-01

    [Purpose] This study was designed to test the effects of the Assistant Chair-Desk System (ACDS), which can reduce the forward tilt of the neck and trunk and the level of fatigue during long lasting study in the sitting position. [Subjects] Fourteen middle school students and 14 college students of mixed gender participated in this study. [Methods] Fatigue level, the trapezius muscle, and the forward tilt angle of the head and trunk as well as distance factors were assessed before after using a normal chair-desk system (NCDS) and the ACDS for 120 minutes. [Results] There was an interaction effect in the angle and length of the neck from the sitting posture changes after 2 hours of studying using the NCDS and ACDS. There were also significant differences in the fatigue levels, hip joint angles and the lengths from the head according to the main effects of the chair-systems. [Conclusion] The studying position while using the ACDS was determined to prevent significant fatigue levels of the muscle and body, provide support to the head, by limiting the forward movement of the neck, and prevent forward tilt of the neck and trunk, by enabling the target point and gaze to be closer to the horizontal direction. PMID:26644668

  3. Electromyography comparison of normal chair-desk system and assistant chair-desk system on fatigue

    PubMed Central

    Kwon, Moon-Seok; Lee, Sang-Ho; Cho, Ik-Rae; Won, Yu-Mi; Han, Mi-Kyung; Jung, Kon-Nym; Lee, Jae-Hee; Chin, Ji-Hyoung; Rho, Jae-Hun; Kim, Ju-Yeon; Yang, Jae-Bong; No, Jae-Kui; Park, Tae-Geun; Lee, Taek-Kyun; Park, Hyo-Joo; Lee, Sam-Jun; Yoo, Kyoung-Seok; Kang, Suh-Jung; Kwon, Se-Jeong; Shin, Mi-Ae; Kim, Hu-Nyun; Kahn, Hyung-Sik; Kim, Min-Jung; Kim, Tae-Young

    2015-01-01

    [Purpose] This study was designed to test the effects of the Assistant Chair-Desk System (ACDS), which can reduce the forward tilt of the neck and trunk and the level of fatigue during long lasting study in the sitting position. [Subjects] Fourteen middle school students and 14 college students of mixed gender participated in this study. [Methods] Fatigue level, the trapezius muscle, and the forward tilt angle of the head and trunk as well as distance factors were assessed before after using a normal chair-desk system (NCDS) and the ACDS for 120 minutes. [Results] There was an interaction effect in the angle and length of the neck from the sitting posture changes after 2 hours of studying using the NCDS and ACDS. There were also significant differences in the fatigue levels, hip joint angles and the lengths from the head according to the main effects of the chair-systems. [Conclusion] The studying position while using the ACDS was determined to prevent significant fatigue levels of the muscle and body, provide support to the head, by limiting the forward movement of the neck, and prevent forward tilt of the neck and trunk, by enabling the target point and gaze to be closer to the horizontal direction. PMID:26644668

  4. Burnout in United States Academic Chairs of Radiation Oncology Programs

    SciTech Connect

    Kusano, Aaron S.; Thomas, Charles R.; DeWeese, Theodore L.; Formenti, Silvia C.; Hahn, Stephen M.; Lawrence, Theodore S.; Mittal, Bharat B.

    2014-02-01

    Purpose: The aims of this study were to determine the self-reported prevalence of burnout in chairs of academic radiation oncology departments, to identify factors contributing to burnout, and to compare the prevalence of burnout with that seen in other academic chair groups. Methods and Materials: An anonymous online survey was administered to the membership of the Society of Chairs of Academic Radiation Oncology Programs (SCAROP). Burnout was measured with the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). Results: Questionnaires were returned from 66 of 87 chairs (76% response rate). Seventy-nine percent of respondents reported satisfaction with their current positions. Common major stressors were budget deficits and human resource issues. One-quarter of chairs reported that it was at least moderately likely that they would step down in the next 1 to 2 years; these individuals demonstrated significantly higher emotional exhaustion. Twenty-five percent of respondents met the MBI-HSS criteria for low burnout, 75% for moderate burnout, and none for high burnout. Group MBI-HSS subscale scores demonstrated a pattern of moderate emotional exhaustion, low depersonalization, and moderate personal accomplishment, comparing favorably with other specialties. Conclusions: This is the first study of burnout in radiation oncology chairs with a high response rate and using a validated psychometric tool. Radiation oncology chairs share similar major stressors to other chair groups, but they demonstrate relatively high job satisfaction and lower burnout. Emotional exhaustion may contribute to the anticipated turnover in coming years. Further efforts addressing individual and institutional factors associated with burnout may improve the relationship with work of chairs and other department members.

  5. Conformational analysis of 9β,19-cyclopropyl sterols: Detection of the pseudoplanar conformer by nuclear Overhauser effects and its functional implications

    PubMed Central

    Nes, W. David; Benson, Mabry; Lundin, Robert E.; Le, Phu H.

    1988-01-01

    Nuclear Overhauser difference spectroscopy and variable temperature studies of the 9β,19-cyclopropyl sterols 24,25-dehydropollinastanol (4,4-desmethyl-5α-cycloart-24-en-3β-ol) and cyclolaudenol [(24S)-24-methyl-5α-cycloart-25(27)-en-3β-ol] have shown the solution conformation of the B/C rings to be twist-chair/twist-boat rather than boat/chair as suggested in the literature. This is very similar to the known crystal structure conformation of 9β,19-cyclopropyl sterols. The effect of these conformations on the molecular shape is highly significant: the first conformation orients into a pseudoplanar or flat shape analogous to lanosterol, whereas the latter conformation exhibits a bent shape. The results are interpreted to imply that, for conformational reasons, cyclopropyl sterols can be expected to maintain the pseudoplanar shape in membrane bilayers. PMID:16593969

  6. Cyclo-biphenalenyl biradicaloid molecular materials: conformation, rearrangement, magnetism, and thermochromism

    SciTech Connect

    Huang, Jingsong; Sumpter, Bobby G; Meunier, Vincent; Tian, Yong-Hui; Kertesz, Prof. Miklos

    2010-01-01

    Cyclo-biphenalenyl biradicaloid molecular materials with chair- and boat-conformations are studied by restricted and broken-symmetry DFT using the M06 family of meta-GGA functionals. The global minima of these molecular materials are magnetically silent due to the sigma-bond connecting the two phenalenyls, while the sigma-bond may undergo low-barrier sigmatropic rearrangements via pi-pi bonded paramagnetic intermediates. The validation of theory is performed for the chair-conformation by comparing the sigma-bonded structures and the rearrangement barriers with experimental data. The boat-conformation is then studied using the validated functional. The electronic spectra of both chair- and boat-conformations are calculated and their applications in thermochromism are discussed.

  7. "Piekara's Chair": Mechanical Model for Atomic Energy Levels.

    ERIC Educational Resources Information Center

    Golab-Meyer, Zofia

    1991-01-01

    Uses the teaching method of models or analogies, specifically the model called "Piekara's chair," to show how teaching classical mechanics can familiarize students with the notion of energy levels in atomic physics. (MDH)

  8. 32. DETAIL OF BOARD ROOM CHAIR WITH SILVER PLATE LISTING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. DETAIL OF BOARD ROOM CHAIR WITH SILVER PLATE LISTING NAMES AND DATES OF PAST OCCUPANTS AND PLATE WITH NAME OF CURRENT OCCUPANT - Philadelphia Saving Fund Society, Twelfth & Market Streets, Philadelphia, Philadelphia County, PA

  9. Remaking the Graduate Curriculum: The Chair as Pragmatic Reformer.

    ERIC Educational Resources Information Center

    Ide, Richard S.

    1992-01-01

    Describes a practical approach to curricular revision from the point of view of a English department chair who presided over the remaking of the graduate curriculum and the hiring of new faculty. (RS)

  10. 82. REGENTS' ROOM WEST WALL, WITH ORIGINAL CHAIRS BY JAMES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    82. REGENTS' ROOM WEST WALL, WITH ORIGINAL CHAIRS BY JAMES RENWICK, JR. MANTELPIECE AND MIRROR ARE NOT ORIGINAL TO THE ROOM. - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  11. Integrating Mathematics with Problem Solving Using the Mathematician's Chair.

    ERIC Educational Resources Information Center

    Hildebrand, Charlene; Ludeman, Clinton J.; Mullin, Joan

    1999-01-01

    Describes an action-research study conducted in a third-grade classroom that integrates mathematical problem solving with the writing process through the use of the Mathematician's Chair. Contains 14 references. (ASK)

  12. [Immersion in a bath despite a safety bath chair].

    PubMed

    Christensen, H B; Lange, A

    1989-01-01

    A case of submersion is described. A mother left her child aged 8 1/2 months sitting in a "safety bath chair" in a full bath and found the child lying under the water shortly afterwards. The infant was hypotonic for a brief period but rapidly recovered without sequelae. Use of a "safety bath chair" gives a false sense of security and its use is warned against. PMID:2911907

  13. Ergonomic surgeon's chair for use during minimally invasive surgery.

    PubMed

    Schurr, M O; Buess, G F; Wieth, F; Saile, H J; Botsch, M

    1999-08-01

    The characteristic working situation in laparoscopic surgery involves elongated instruments and limited mobility of the surgeon during the operation. These circumstances require new technical solutions to enhance the surgeon's comfort. In other surgical fields with special ergonomic situations, such as microsurgery, some surgeons prefer to operate from a seated position at the operating room table. We developed a new surgeon's chair dedicated to the ergonomic and functional requirements of laparoscopic surgery. The chair allows the surgeon to maintain a semi-standing position during the operation. Foot pedals for high frequency and suction/irrigation are integrated into the base of the chair. The pedals are purposely aligned to be comparable to foot pedals in a car. The chair is driven by electromotors, controlled with a special foot switch that operates independent of assisting personnel during surgery. Initial clinical testing of the chair could prove the theory that supporting the surgeon with a cockpit type of operating room chair helps to avoid fatigue during long endoscopic procedures. Such assistance is especially important in combination with robotic devices for use during solo surgery. PMID:10871169

  14. Substrate conformational transitions in the active site of chorismate mutase: Their role in the catalytic mechanism

    PubMed Central

    Guo, Hong; Cui, Qiang; Lipscomb, William N.; Karplus, Martin

    2001-01-01

    Chorismate mutase acts at the first branch-point of aromatic amino acid biosynthesis and catalyzes the conversion of chorismate to prephenate. The results of molecular dynamics simulations of the substrate in solution and in the active site of chorismate mutase are reported. Two nonreactive conformers of chorismate are found to be more stable than the reactive pseudodiaxial chair conformer in solution. It is shown by QM/MM molecular dynamics simulations, which take into account the motions of the enzyme, that when these inactive conformers are bound to the active site, they are rapidly converted to the reactive chair conformer. This result suggests that one contribution of the enzyme is to bind the more prevalent nonreactive conformers and transform them into the active form in a step before the chemical reaction. The motion of the reactive chair conformer in the active site calculated by using the QM/MM potential generates transient structures that are closer to the transition state than is the stable CHAIR conformer. PMID:11481470

  15. Influence of chair vibrations on indoor sonic boom annoyance

    NASA Astrophysics Data System (ADS)

    Rathsam, Jonathan; Klos, Jacob; Loubeau, Alexandra

    2015-10-01

    One goal of NASA's Commercial Supersonic Technology Project is to identify candidate noise metrics suitable for regulating quiet sonic boom aircraft. A suitable metric must consider the short duration and pronounced low frequency content of sonic booms. For indoor listeners, rattle and creaking sounds and floor and chair vibrations may also be important. The current study examined the effect of such vibrations on the annoyance of test subjects seated indoors. The study involved two chairs exposed to nearly identical acoustic levels: one placed directly on the floor, and the other isolated from floor vibrations by pneumatic elastomeric mounts. All subjects experienced both chairs, sitting in one chair for the first half of the experiment and the other chair for the remaining half. Each half of the experiment consisted of 80 impulsive noises played at the exterior of the sonic boom simulator. When all annoyance ratings were analyzed together there appeared to be no difference in mean annoyance with isolation condition. When the apparent effect of transfer bias was removed, a subtle but measurable effect of vibration on annoyance was identified.

  16. Influence of Chair Vibrations on Indoor Sonic Boom Annoyance

    NASA Technical Reports Server (NTRS)

    Rathsam, Jonathan; Klos, Jacob; Loubeau, Alexandra

    2015-01-01

    One goal of NASA’s Commercial Supersonic Technology Project is to identify candidate noise metrics suitable for regulating quiet sonic boom aircraft. A suitable metric must consider the short duration and pronounced low frequency content of sonic booms. For indoor listeners, rattle and creaking sounds and floor and chair vibrations may also be important. The current study examined the effect of such vibrations on the annoyance of test subjects seated indoors. The study involved two chairs exposed to nearly identical acoustic levels: one placed directly on the floor, and the other isolated from floor vibrations by pneumatic elastomeric mounts. All subjects experienced both chairs, sitting in one chair for the first half of the experiment and the other chair for the remaining half. Each half of the experiment consisted of 80 impulsive noises played at the exterior of the sonic boom simulator. When all annoyance ratings were analyzed together there appeared to be no difference in mean annoyance with isolation condition. When the apparent effect of transfer bias was removed, a subtle but measurable effect of vibration on annoyance was identified.

  17. Vapochromic Behavior of a Chair-Shaped Supramolecular Metallacycle with Ultra-Stability.

    PubMed

    Jiang, Bo; Zhang, Jing; Ma, Jian-Qiu; Zheng, Wei; Chen, Li-Jun; Sun, Bin; Li, Chao; Hu, Bing-Wen; Tan, Hongwei; Li, Xiaopeng; Yang, Hai-Bo

    2016-01-27

    A new discrete supramolecular metallacycle functionalized with an alkynylplatinum(II) bzimpy moiety was successfully prepared via coordination-driven self-assembly, and it displayed a reversible color change in the solid state between yellow and red, triggered by CH2Cl2 vapor or mechanical grinding. Notably, unlike many known vapochromic systems, the obtained vapochromic metallacycle exhibits ultra-stability, with the red color remaining unchanged in air for several months at room temperature or even under vacuum for >1 week. Further investigation revealed that the chair conformation of the metallacyclic scaffold, which was thought to prevent intermolecular steric repulsion between the alkyl chain and triethylphosphine, favored close molecular stacking through intermolecular Pt···Pt and π-π stacking interactions, thus allowing such vapochromic behavior with ultra-stability. PMID:26741405

  18. [Assessment of a hospital bath chair: an ergonomic approach].

    PubMed

    Comélio, Maria Estevam; Alexandre, Neusa Maria Costa

    2005-01-01

    A high rate of musculoskeletal disorders in members of the nursing team is observed in the literature. The use of special devices such as the bath chair has reduced the risk of back injuries in these workers and has also provided the patient with greater safety as well as comfort. The aim of the present study was to assess the ergonomic characteristics of a bath chair utilized in a hospital Separate questionnaires were applied for the nurses and the patients. The bath chair accessories presented several ergonomic problems. The perceived physical exertion according to the Borg-CR10 Scale indicated that a high level of exertion was required to manipulate the equipment (8.33). PMID:16514945

  19. Jaczko to resign as chair of Nuclear Regulatory Commission

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-05-01

    Gregory Jaczko, chair of the U.S. Nuclear Regulatory Commission (NRC), announced on 21 May that he will resign once his successor is appointed. His resignation will end a stormy 3-year chairmanship during which he was accused of bullying NRC staff, lying to Congress, and being too close to the political process. Jaczko formerly served as science advisor to Sen. Harry Reid (D-Nev.). As NRC chair, Jaczko halted the commission's license application review for storing nuclear waste at Nevada's Yucca Mountain. In addition, during his NRC tenure the commission focused on identifying and implementing lessons from Japan's Fukushima Daiichi reactors damaged by the 2011 tsunami.

  20. Patients' choice of portable folding chairs to reduce symptoms of orthostatic hypotension

    NASA Technical Reports Server (NTRS)

    Smit, A. A.; Wieling, W.; Opfer-Gehrking, T. L.; van Emmerik-Levelt, H. M.; Low, P. A.

    1999-01-01

    Patients with neurogenic orthostatic hypotension may use portable folding chairs to prevent or reduce symptoms of low blood pressure. However, a concomitant movement disorder may limit the use of these chairs in daily living. In this prospective study, 13 patients with orthostatic hypotension, balance disturbance associated with motor disability, or both examined three commercially available portable folding chairs. A questionnaire was used to document the characteristics in chair design that were relevant for satisfactory use to these patients. Armrests, seat width, and an adjustable sitting height were found to be important features of a portable folding chair. One chair was selected by 11 of 13 patients to fit most needs.

  1. 21 CFR 890.3110 - Electric positioning chair.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Electric positioning chair. 890.3110 Section 890.3110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3110...

  2. 21 CFR 890.3110 - Electric positioning chair.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Electric positioning chair. 890.3110 Section 890.3110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3110...

  3. 21 CFR 890.3110 - Electric positioning chair.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Electric positioning chair. 890.3110 Section 890.3110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3110...

  4. 21 CFR 890.3110 - Electric positioning chair.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Electric positioning chair. 890.3110 Section 890.3110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3110...

  5. Competency Assessment and Human Resource Management of County Extension Chairs.

    ERIC Educational Resources Information Center

    Lindner, James R.

    The purpose of this descriptive and correlational study was to examine perceptions of Ohio State University Extension county chairs regarding their human resource management competencies and performance of human resource management activities. The study also sought to describe the relationship between human resource management competencies and…

  6. Strategies for establishing an endowed chair in a service setting.

    PubMed

    Randhawa, Simmy; Robinson, Nellie C; Feetham, Suzanne; Church, Tracy; Hinds, Pamela S; Talley, Linda B; Williams, Catherine

    2014-01-01

    To advance care for patients and families requires that providers and administrators in clinical settings place a high priority on the scientific domain of nursing. New knowledge intended to benefit nursing care is most effectively and efficiently achieved when a vibrant and well-supported nursing research program is embedded within a health care system. An endowed chair in nursing research is an esteemed strategy acknowledging the contributions of nursing science, providing credibility to a researcher and research programs, and demonstrating commitment to the infrastructure for nursing research. Organizational readiness through leadership; systems thinking; relationship development; and knowledge of the dynamics, process, and expectations of philanthropy are essential to establishing an endowed chair. Philanthropic endeavors can be used to strategically develop a high-impact campaign that resonates across public and private sectors to secure funding to solidify and advance nursing research. By actively engaging stakeholders including system leaders, frontline nurses, and other care providers and development leaders, a successful campaign can establish and sustain an endowed chair in nursing research. This article describes the stakeholders, processes, structure, and outcomes for the first endowed chair in nursing research at Children's National Health System in Washington, DC. PMID:25208148

  7. When Women Are Equal: The Canada Research Chair Experience

    ERIC Educational Resources Information Center

    Grant, Karen R.; Drakich, Janice

    2011-01-01

    This paper focuses on the gendered nature of elite academic careers. Of interest is how similar or different the experiences are of women and men who have been appointed to Canada Research Chairs (CRCs). In particular, we examine the impacts of holding a CRC position and consider the factors that shape that experience for women and men. Based on…

  8. 21 CFR 890.3110 - Electric positioning chair.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electric positioning chair. 890.3110 Section 890.3110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3110...

  9. Chairing and Caring: Gendered Dimensions of Leadership in Academe

    ERIC Educational Resources Information Center

    Acker, Sandra

    2012-01-01

    This article uses three frames of analysis, each with gendered implications, to interpret the author's narrative of experience as a department chair (head of department) in a Canadian university from 1999 to 2002. The narrative is based not only on memory but on transcripts of interviews conducted with the author at various points during her term…

  10. 30. LAUNCH CONTROL CAPSULE. ACOUSTICAL ENCLOSURE. OPERATORS' CHAIR AND COMMUNICATIONS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. LAUNCH CONTROL CAPSULE. ACOUSTICAL ENCLOSURE. OPERATORS' CHAIR AND COMMUNICATIONS CONSOLE IN FOREGROUND. ELECTRONIC EQUIPMENT RACK AT LEFT; LAUNCH CONTROL CONSOLE WITH CAPTAIN JAMES L. KING, JR. IN CENTER. LIEUTENANT KEVIN R. MCCLUNEY IN BACKGROUND. VIEW TO SOUTHEAST. - Minuteman III ICBM Launch Control Facility November-1, 1.5 miles North of New Raymer & State Highway 14, New Raymer, Weld County, CO

  11. Managing People: A Guide for Department Chairs and Deans.

    ERIC Educational Resources Information Center

    Leaming, Deryl R., Ed.

    This book is a collection of essays by experienced department chairs, deans, and vice-presidents. Each essay discusses a different aspect of people management in higher education, explaining the issues and offering suggestions and resources. The chapters are: (1) "Understanding Yourself" (Deryl R. Leaming); (2) "Understanding and Communicating…

  12. The analytic setting today: using the couch or the chair?

    PubMed

    Wiener, Jan

    2015-09-01

    This paper re-visits Murray Jackson's 1961 paper in the Journal of Analytical Psychology, 'Chair, couch and countertransference', with the aim of exploring the role of the couch for Jungian analysts in clinical practice today. Within the Society of Analytical Psychology (SAP) and some other London-based societies, there has been an evolution of practice from face-to-face sessions with the patient in the chair, as was Jung's preference, to a mode of practice where patients use the couch with the analyst sitting to the side rather than behind, as has been the tradition in psychoanalysis. Fordham was the founding member of the SAP and it was because of his liaison with psychoanalysis and psychoanalysts that this cultural shift came about. Using clinical examples, the author explores the couch/chair question in terms of her own practice and the internal setting as a structure in her mind. With reference to Bleger's (2013) paper 'Psychoanalysis of the psychoanalytic setting', the author discusses how the analytic setting, including use of the couch or the chair, can act as a silent container for the most primitive aspects of the patient's psyche which will only emerge in analysis when the setting changes or is breached. PMID:26274847

  13. Presidents and Chairs on Common Ground: Handling Flashpoints Together

    ERIC Educational Resources Information Center

    Fletcher, Donald H.; Maxwell, David E.

    2011-01-01

    In the face of public controversies, presidents and board chairs are often called upon to resolve difficult and divisive issues. When they are faced with public controversies and other challenges, a strong working relationship grounded in mutual respect and trust can make the difference between meeting the challenge head on and falling behind.…

  14. 7 CFR 1900.6 - Chair, Loan Resolution Task Force.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... under 7 CFR part 1951, subpart S; (b) The responsibility for making and directing the making of loan... servicing rights and pre-acceleration homestead and preservation loan servicing rights under 7 CFR part 1951... 7 Agriculture 12 2011-01-01 2011-01-01 false Chair, Loan Resolution Task Force. 1900.6...

  15. 7 CFR 1900.6 - Chair, Loan Resolution Task Force.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... under 7 CFR part 1951, subpart S; (b) The responsibility for making and directing the making of loan... servicing rights and pre-acceleration homestead and preservation loan servicing rights under 7 CFR part 1951... 7 Agriculture 12 2012-01-01 2012-01-01 false Chair, Loan Resolution Task Force. 1900.6...

  16. 7 CFR 1900.6 - Chair, Loan Resolution Task Force.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... under 7 CFR part 1951, subpart S; (b) The responsibility for making and directing the making of loan... servicing rights and pre-acceleration homestead and preservation loan servicing rights under 7 CFR part 1951... 7 Agriculture 12 2013-01-01 2013-01-01 false Chair, Loan Resolution Task Force. 1900.6...

  17. 7 CFR 1900.6 - Chair, Loan Resolution Task Force.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... under 7 CFR part 1951, subpart S; (b) The responsibility for making and directing the making of loan... servicing rights and pre-acceleration homestead and preservation loan servicing rights under 7 CFR part 1951... 7 Agriculture 12 2010-01-01 2010-01-01 false Chair, Loan Resolution Task Force. 1900.6...

  18. 7 CFR 1900.6 - Chair, Loan Resolution Task Force.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... primary servicing rights and pre-acceleration homestead and preservation loan servicing rights under 7 CFR... and pre-acceleration homestead and preservation loan servicing rights under 7 CFR part 1951, subpart S... 7 Agriculture 12 2014-01-01 2013-01-01 true Chair, Loan Resolution Task Force. 1900.6 Section...

  19. Chairs, Cars, and Bridges: Teaching Aesthetics from the Everyday

    ERIC Educational Resources Information Center

    Zande, Robin Vande

    2007-01-01

    It is very typical for students in K-12 art education to study aesthetics based on artistic objects. Artistic objects, however, need not be the sole source for aesthetic investigation. In this article, the author discusses the use of designed objects such as chairs, cars, and bridges in the discussion of aesthetic concepts. Students, as consumers…

  20. The Cost of Academic Leadership: Department Chair Stress.

    ERIC Educational Resources Information Center

    Gmelch, Walter H.; Burns, John S.

    1993-01-01

    A study of 564 college and university department heads investigated the most stressful situations, emergent themes, and differences between department chair and faculty stressors. Most stress came from heavy workload, time pressures, confrontations with colleagues, organizational constraints, and faculty duties. Faculty and administrative…

  1. 21 CFR 880.6140 - Medical chair and table.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical chair and table. 880.6140 Section 880.6140 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use...

  2. Bourdieu, Department Chairs and the Reform of Science Education

    ERIC Educational Resources Information Center

    Melville, Wayne; Hardy, Ian; Bartley, Anthony

    2011-01-01

    Using the insights of the French sociologist, Pierre Bourdieu, this article considers the role of the science department chair in the reform of school science education. Using Bourdieu's "thinking tools" of "field", "habitus" and "capital", we case study the work of two teachers who both actively pursue the teaching and learning of science as…

  3. Human Research Program 2010 Chair Standing Review Panel Meeting

    NASA Technical Reports Server (NTRS)

    Steinberg, Susan

    2011-01-01

    The 13 Human Research Program (HRP) Standing Review Panel (SRP) Chairs, and in some cases one or two additional panel members (see section XIV, roster) referred to as the Chair (+1) SRP throughout this document, met at the NASA Johnson Space Center (JSC) on December 7, 2010 to allow the HRP Elements and Projects to report on their progress over the past year, their current status, and their plans for the upcoming year based on NASA's current goals and objectives for human space exploration. A large focus of the meeting was also used to discuss integration across the HRP scientific disciplines based on a recommendation from the 2009 HRP SRP review. During the one-day meeting, each of the HRP Elements and Projects presented the changes they made to the HRP Integrated Research Plan (IRP Rev. B) over the last year, and what their top three areas of integration are between other HRP Elements/Projects. The Chair (+1) SRP spent sufficient time addressing the panel charge, either as a group or in a separate closed session, and the Chair (+1) SRP and the HRP presenters and observers, in most cases, had sufficient time to discuss during and after the presentations. The SRP made a final debriefing to the HRP Program Scientist, Dr. John B. Charles, prior to the close of the meeting on December 7, 2010. Overall, the Chair (+1) SRP concluded that most of the HRP Elements/Projects did a commendable job during the past year in addressing integration across the HRP scientific disciplines with the available resources. The Chair (+1) SRP agreed that the idea of integration between HRP Elements/Projects is noble, but believes all parties involved should have the same definition of integration, in order to be successful. The Chair (+1) SRP also believes that a key to successful integration is communication among the HRP Elements/Projects which may present a challenge. The Chair (+1) SRP recommends that the HRP have a workshop on program integration (with HRP Element

  4. The importance of polarizability: comparison of models of carbon disulphide in the ionic liquids [C1C1im][NTf2] and [C4C1im][NTf2].

    PubMed

    Lynden-Bell, Ruth M; Quitevis, Edward L

    2016-06-28

    The local environment of CS2 and in solution in two ionic liquids ([C1C1im][NTf2] and [C4C1im][NTf2]) are investigated by atomistic simulation and compared with that in neat CS2. The intermolecular vibrational densities of states of CS2 are calculated and compared with experimental OHD-RIKES spectra. The fair agreement of the results from solutions but poor agreement of the results from neat CS2 suggest that while collective effects are unimportant in solutions, they have a major effect on the OHD-RIKES spectrum of neat CS2. Comparing polarizable and unpolarizable models for CS2 emphasizes the importance of polarizability in determining local structure. PMID:27273458

  5. Decision-Making Styles of Department Chairs at Public Jordanian Universities: A High-Expectancy Workforce

    ERIC Educational Resources Information Center

    Khasawneh, Samer; Alomari, Aiman; Abu-tineh, Abdullah

    2011-01-01

    The primary purpose of this study was to determine the decision-making styles of department chairs employed by three public institutions in Jordan. A total of 95 department chairs participated in the study by completing the General Decision-Making Styles survey. The results indicated that department chairs under study have the rational…

  6. Faculty Recruitment and Retention: A Case Study of the Chair's Role.

    ERIC Educational Resources Information Center

    Miller, Michael; Jackson, JoAnne C.; Pope, Myron L.

    This document states that many studies have identified faculty recruitment as a specific job responsibility of college department chairs. Because the recruitment process is time consuming and costly, the chair must also ensure that recruitment leads to retention. This paper closely examines what strategies academic chairs use to recruit and retain…

  7. The Role of the Academic Department Chair in ADA Student Accommodations.

    ERIC Educational Resources Information Center

    Morehouse, Percy A., Jr.; Becker, George; Combs, Lee

    The academic department chair has a pivotal role in the administration of special accommodations provided to students under the provisions of the Americans with Disabilities Act and Section 504 of the Rehabilitation Act of 1973. Department chairs may interact with all levels of the institution, and the interaction among chairs, the Equal…

  8. Department Chair Advice on Teaching and Research at U.S. Research Universities

    ERIC Educational Resources Information Center

    Taggart, Gabel

    2015-01-01

    Using data from a 2010 survey of academic chairs, this study reports on academic department chairs' recommended time allocations to new assistant professors. I contend that personal values about research and teaching influence the department chair's recommendations along with organizational characteristics. Multi-level modeling indicates that…

  9. The Internal Conflict Experienced by Public Community College Academic Department Chairs

    ERIC Educational Resources Information Center

    Johnson, Raymonda T.

    2010-01-01

    The focus of this research is the conflicted nature of the lived experience of public community college academic department chairs. In many colleges, department chairs are faculty chosen by colleagues and/or administration. Once selected, chairs assume supervisory responsibilities. The duality of this colleague-supervisor role has the potential…

  10. Transition into the Department Chair Role: The Manager-Leader Continuum

    ERIC Educational Resources Information Center

    Crowder, James

    2010-01-01

    The Department Chair position is perhaps the most important position on a college campus. Not only do Department Chairs have a large number of individual tasks to perform, but a Chair's actions have potentially large repercussions, since the bulk of the pedagogical and administrative decisions made at institutions of higher education are made at…

  11. An Interview With Chapman Conference Chair Venkat Lakshmi

    NASA Astrophysics Data System (ADS)

    McCarter-Joseph, Tricia

    2013-07-01

    AGU's Chapman Conference program has been facilitating small collaborative meetings on topical and specialized subjects for more than 35 years. These meetings allow for debate and an exploration of possible solutions to scientific problems, while providing a professional networking opportunity for younger scientists. Venkat Lakshmi, professor of hydrology, climate, and water resources and former chair of the Department of Earth and Ocean Sciences at the University of South Carolina, was selected in January as the Chapman Conference program chair through 2015. Lakshmi, a former Eos editor, recalls with enthusiasm organizing a 2012 Chapman Conference in Hawaii: the proposal writing, the grant writing, soliciting presenters, and gathering scientific material. He is now using his experience organizing meetings and mentoring students at his university to help advance the Chapman program. Eos spoke with him about his new role and his vision for the program.

  12. Roles, responsibilities, and outcome expectations of endowed chairs in nursing.

    PubMed

    Bushy, Angeline; Dunkin, Jeri W; Stover, Lynn

    2005-01-01

    This study, using a modified Delphi approach, examines the purpose, roles, responsibilities, and outcomes of endowed chairholders in nursing. Deans and faculty who hold endowed chairs participated in this 3-phased study. While the ranking of importance varied between these 2 groups of experts, common themes emerged relative to the phenomenon under investigation. Findings from this preliminary work can be used by deans and chairholders to develop job descriptions and evaluate the impact of endowments in a program of nursing. PMID:16030455

  13. Musical Chairs: An Innovative Teaching and Learning Method

    ERIC Educational Resources Information Center

    Kuo, Ya-Hui

    2010-01-01

    How teaching and learning takes place in classrooms can be easily seen by the way classrooms are set up: Students' desks and chairs are arranged in rolls while teachers' desks are up front. Yet, why must teachers be the ones who lecture, why can't it be students? Would it be better or worse when teachers are the receivers and the students are the…

  14. Analysis of sitting forces on stationary chairs for daily activities.

    PubMed

    Hu, Lingling; Tackett, Bob; Tor, Onder; Zhang, Jilei

    2016-04-01

    No literature related to the study of sitting forces on chairs sat on by people who weighed over 136 kg was found. The Business Institutional Furniture Manufactures Association needs force data for development of performance test standards to test chairs for users who weigh up to 181 kg. 20 participants who weighed from 136 to 186 kg completed 6 tasks on an instrumented chair in the sequence of sitting down, remaining seated and rising. Effects of sitting motion, armrest use and seat cushion thickness on vertical sitting forces and centre-of-force were investigated. Results indicated hard sitting down yielded the highest sitting force of 213% in terms of participants' body weights. Armrest use affected sitting forces of normal sitting down, but not of rising and hard sitting down. Cushion thickness affected sitting forces of normal and hard sitting down and shifting, but not of rising, static seating or stretching backward situations. Practitioner Summary: Results of the sitting force and centre-of-force data obtained for this research can help furniture manufacturers develop new product performance test standards for creating reliable engineering design and manufacturing quality and durable products to meet a niche market need. PMID:26257071

  15. Bourdieu, Department Chairs and the Reform of Science Education

    NASA Astrophysics Data System (ADS)

    Melville, Wayne; Hardy, Ian; Bartley, Anthony

    2011-11-01

    Using the insights of the French sociologist, Pierre Bourdieu, this article considers the role of the science department chair in the reform of school science education. Using Bourdieu's 'thinking tools' of 'field', 'habitus' and 'capital', we case study the work of two teachers who both actively pursue the teaching and learning of science as inquiry. One teacher, Dan, has been a department chair since 2000, and has actively encouraged his department to embrace science as inquiry. The other teacher, Leslie, worked for one year in Dan's department before being transferred to another school where science teaching continues to be more traditional. Our work suggests that there are three crucial considerations for chairs seeking to lead the reform of science teaching within their department. The first of these is the development of a reform-minded habitus, as this appears to be foundational to the capital that can be expended in the leadership of reform. The second is an understanding of how to wield power and position in the promotion of reform. The third is the capacity to operate simultaneously and strategically within, and across, two fields; the departmental field and the larger science education field. This involves downplaying administrative logics, and foregrounding more inquiry-focused logics as a vehicle to challenge traditional science-teaching dispositions-the latter being typically dominated by concerns about curriculum 'coverage'.

  16. Gradient and mc scf calculations of the conformers and the formation of primary ethylene ozonide

    NASA Astrophysics Data System (ADS)

    Ruoff, Peter; Sæbø, Svein; Almlöf, Jan

    1981-11-01

    The confonners of primary ethylene ozonide have been studied by ab initio gradient and MC SCF calculations. At the MC SCF level they are more spread in energy than in SCF calculations. The planar conformer, carbon-carbon half chair and the oxygen envelope are much higher m energy than the other conformers. The MC SCF activation energy for cyclo-addition of ozone and ethylene is 91-99 kJ/mole.

  17. AACP Strategy for Addressing the Professional Development Needs of Department Chairs

    PubMed Central

    Rodriguez, Tobias E.; Weinstein, George; Sorofman, Bernard A.; Bosso, John A.; Kerr, Robert A.; Haden, N. Karl

    2012-01-01

    Objectives. Characterize the skills and abilities required for department chairs, identify development needs, and then create AACP professional development programs for chairs. Methods. A 30-question electronic survey was sent to AACP member department chairs related to aspects of chairing an academic department. Results. The survey identified development needs in the leadership, management, and personal abilities required for effective performance as department chair. The information was used to prioritize topics for subsequent AACP development programs. Subsequent programs conducted at AACP Interim and Annual Meetings were well attended and generally received favorable reviews from participants. A list of development resources was placed on the AACP website. Conclusions. This ongoing initiative is part of an AACP strategy to identify and address the professional development needs of department chairs. Survey results may also inform faculty members and other academic leaders about the roles and responsibilities of department chairs. PMID:22919099

  18. Conformation effects on the molecular orbitals of serine

    NASA Astrophysics Data System (ADS)

    Wang, Ke-Dong; Ma, Peng-Fei; Shan, Xu

    2011-03-01

    This paper calculates the five most stable conformers of serine with Hartree—Fock theory, density functional theory (B3LYP), Møller—Plesset perturbation theory (MP4(SDQ)) and electron propagation theory with the 6-311++G(2d,2p) basis set. The calculated vertical ionization energies for the valence molecular orbitals of each conformer are in agreement with the experimental data, indicating that a range of molecular conformations would coexist in an equilibrium sample. Information of the five outer valence molecular orbitals for each conformer is explored in coordinate and momentum spaces using dual space analysis to investigate the conformational processes, which are generated from the global minimum conformer Ser1 by rotation of C2-C3 (Ser4), C1-C2 (Ser5) and C1-O2 (Ser2 and Ser3). Orbitals 28a, 27a and 26a are identified as the fingerprint orbitals for all the conformational processes. Project supported by the Doctoral Research Fund of Henan Normal University, China (Grant No. 525449).

  19. Attitudinal Conformity and Anonymity

    ERIC Educational Resources Information Center

    Tyson, Herbert; Kaplowitz, Stan

    1977-01-01

    Tested college students for conformity when conditions contributing to conformity were absent. Found that social pressures (responding in public, being surveyed by fellow group members) are necessary to produce conformity. (RL)

  20. The Department Chair as Academic Leader. American Council on Education/Oryx Press Series on Higher Education.

    ERIC Educational Resources Information Center

    Hecht, Irene W. D.; Higgerson, Mary Lou; Gmelch, Walter H.; Tucker, Allan

    This book provides a comprehensive guide to the role of the academic department chair in a time when the chair's role is rapidly becoming more important and more complex. Part 1 describes the new roles chairs face, followed by a general discussion of their responsibilities. Part 2 is concerned with the department chair's work with people,…

  1. Shaking infant trauma induced by misuse of a baby chair.

    PubMed

    de San Lazaro, C; Harvey, R; Ogden, A

    2003-07-01

    A 2 month old infant presented with bilateral subdural haemorrhages and bilateral subhyaloid haemorrhage. The parent admitted to forceful bouncing of the child in a baby rocker. Experiments showed that violent rocking in the chair could produce extreme alternating acceleration/deceleration forces in excess of those induced by shaking alone. Such handling could not be interpreted as accidental mismanagement and the abusive nature of the process was graphically shown in video recordings of the experiment. Prosecution resulted in a conviction for cruelty, and a suspended sentence. PMID:12818916

  2. Synthesis and Properties of the Heterospin (S1 = S2 = (1)/2) Radical-Ion Salt Bis(mesitylene)molybdenum(I) [1,2,5]Thiadiazolo[3,4-c][1,2,5]thiadiazolidyl.

    PubMed

    Pushkarevsky, Nikolay A; Semenov, Nikolay A; Dmitriev, Alexey A; Kuratieva, Natalia V; Bogomyakov, Artem S; Irtegova, Irina G; Vasilieva, Nadezhda V; Bode, Bela E; Gritsan, Nina P; Konstantinova, Lidia S; Woollins, J Derek; Rakitin, Oleg A; Konchenko, Sergey N; Ovcharenko, Victor I; Zibarev, Andrey V

    2015-07-20

    Low-temperature interaction of [1,2,5]thiadiazolo[3,4-c][1,2,5]thiadiazole (1) with MoMes2 (Mes = mesitylene/1,3,5-trimethylbenzene) in tetrahydrofuran gave the heterospin (S1 = S2 = (1)/2) radical-ion salt [MoMes2](+)[1](-) (2) whose structure was confirmed by single-crystal X-ray diffraction (XRD). The structure revealed alternating layers of the cations and anions with the Mes ligands perpendicular, and the anions tilted by 45°, to the layer plane. At 300 K the effective magnetic moment of 2 is equal to 2.40 μB (theoretically expected 2.45 μB) and monotonically decreases with lowering of the temperature. In the temperature range 2-300 K, the molar magnetic susceptibility of 2 is well-described by the Curie-Weiss law with parameters C and θ equal to 0.78 cm(3) K mol(-1) and -31.2 K, respectively. Overall, the magnetic behavior of 2 is similar to that of [CrTol2](+)[1](-) and [CrCp*2](+)[1](-), i.e., changing the cation [MAr2](+) 3d atom M = Cr (Z = 24) with weak spin-orbit coupling (SOC) to a 4d atom M = Mo (Z = 42) with stronger SOC does not affect macroscopic magnetic properties of the salts. For the XRD structure of salt 2, parameters of the Heisenberg spin-Hamiltonian were calculated using the broken-symmetry DFT and CASSCF approaches, and the complex 3D magnetic structure with both the ferromagnetic (FM) and antiferromagnetic (AF) exchange interactions was revealed with the latter as dominating. Salt 2 is thermally unstable and slowly loses the Mes ligands upon storage at ambient temperature. Under the same reaction conditions, interaction of 1 with MoTol2 (Tol = toluene) proceeded with partial loss of the Tol ligands to afford diamagnetic product. PMID:26121418

  3. A biomechanical and ergonomic evaluation of patient transferring tasks: wheelchair to shower chair and shower chair to wheelchair.

    PubMed

    Garg, A; Owen, B; Beller, D; Banaag, J

    1991-04-01

    A laboratory study was conducted to evaluate five different manual techniques (two-person manual lifting; rocking and pulling the patient using a gait belt with two persons; walking belt with one and two persons) and three different mechanical hoists (Hoyer lift, Trans-Aid and Ambulift) for transferring patients from wheelchair to shower chair and shower chair to wheelchair. Six female nursing students with prior patient transfer experience served both as nurses and as passive patients. Static biomechanical evaluation showed that the mean trunk flexion moments, erector spinae muscle forces and compressive and shear forces at the L5S1 disc for the four pulling methods ranged from 92 to 125 Nm, 1845 to 2507 N, 1973 to 2641 N and 442 to 580 N, respectively, as compared to about 213 Nm, 4260 N, 5050 N and 926 N for two-person manual lifting. Perceived stress ratings for the shoulder, upper back, lower back and whole body were significantly lower for pulling methods than those for lifting the patient (p less than or equal to 0.01). Patients found pulling techniques, except the gait belt, to be more comfortable and secure than the lifting method (p less than or equal to 0.01). However, most of the nurses believed that Medesign and the one-person walking belt would not work on those patients who cannot bear weight and those who are heavy, contracted or combative. A two-person walking belt was the most preferred method. Two out of three hoists (Hoyer lift and Trans-Aid) were perceived by the nurses to be more stressful than one- and two-person walking belts. The patients found these two hoists to be more uncomfortable and less secure than with three of the five manual methods (one- and two-person walking belts and Medesign). Pulling techniques and hoists took significantly longer amounts of time to make the transfer than manually lifting the patient (p less than or equal to 0.01). The two-person walking belt, using a gentle rocking motion to utilize momentum and a pulling

  4. Multidisciplinary approach to converting power chair into motorized prone cart.

    PubMed

    Brose, Steven W; Wali, Eisha

    2014-01-01

    Pressure ulcers remain a major source of morbidity and mortality in veterans with neurologic impairment. Management of pressure ulcers typically involves pressure relief over skin regions containing wounds, but this can lead to loss of mobility and independence when the wounds are located in regions that receive pressure from sitting. An innovative, low-cost, multidisciplinary effort was undertaken to maximize quality of life in a veteran with a thoracic-4 level complete spinal cord injury and a stage 4 ischial wound. The person's power wheelchair was converted into a motorized prone cart, allowing navigation of the Department of Veterans Affairs spinal cord injury hospital ward and improved socialization while relieving pressure on the wound. Physical and occupational therapy assisted with the reconfiguration of the power chair and verified safe transfers into the chair and driving of the device. Psychology verified positive psychosocial benefit, while nursing and physician services verified an absence of unwanted pain or skin injury resulting from use of the device. Further investigation of ways to apply this technique is warranted to improve the quality of life of persons with pressure ulcers. PMID:25786192

  5. A competency-based approach to recruiting, developing, and giving feedback to department chairs.

    PubMed

    Palmer, Megan; Hoffmann-Longtin, Krista; Walvoord, Emily; Bogdewic, Stephen P; Dankoski, Mary E

    2015-04-01

    Academic health centers (AHCs) are under unprecedented pressure, making strong leadership during these challenging times critical. Department chairs have tremendous influence in their AHCs, yet data indicate that--despite outstanding academic credentials--they are often underprepared to take on these important leadership roles. The authors sought to improve the approach to recruiting, developing, and giving feedback to department chairs at their institution, the Indiana University School of Medicine (IUSM), by reorganizing these processes around six key leadership competencies: leadership and team development, performance and talent management, vision and strategic planning, emotional intelligence, communication skills, and commitment to the tripartite mission. Over a two-year period (2009-2011), IUSM faculty and administrators developed standardized recruitment procedures to assess potential chairs based on the six leadership domains, and searches are now streamlined through centralized staff support in the dean's office. Additionally, IUSM offers a chair development series to support learning around these leadership competencies and to meet the stated professional development needs of the chairs. Finally, chairs receive structured feedback regarding their leadership (among other considerations) through two different assessment instruments, IUSM's Department Chair 360° Leadership Survey and IUSM's Faculty Vitality Survey--both of which the dean reviews annually. Strategically attending to the way that chairs are selected, developed, and given feedback has tremendous potential to increase the success of chairs and, in turn, to constructively shape the culture of AHCs. PMID:25607939

  6. Executive onboarding: ensuring the success of the newly hired department chair.

    PubMed

    Ross, Warren E; Huang, Karen H C; Jones, Greg H

    2014-05-01

    The success of newly recruited medical school department chairs has become increasingly important for achievement of organizational goals. An effective onboarding program for these chairs can greatly facilitate early success, as well as satisfaction of the new hire with the position and the school. Onboarding programs can include traditional orientation items such as payroll signup and parking details, but should focus heavily on sharing organizational structure, culture, and how things get done. The goals of onboarding will be well served by implementation of three roles in the process. An Orientation Navigator can assist the new chair in the orientation phase, completing new employee documents and navigating the day-to-day challenges of working at the location. A Peer Mentor, generally a sitting chair, serves as both "buddy" and mentor, providing moral support as well as ensuring that the new chair gains an understanding of the people and processes important for getting things done. A Transition Mentor serves over a longer term as a sounding board and coach outside the peer group, assisting in a variety of ways to promote the chair's growth, development, and success as a leader. Finally, any onboarding process is significantly compromised without the active participation of the dean, meeting regularly with the chair to clarify expectations, promote assimilation, and solve problems. Successful onboarding begins with a mindfulness of the needs of the newly hired chair, and a well-designed and well-implemented plan will have wide-ranging benefits for the chair and the organization. PMID:24667516

  7. Interpreting medium ring canonical conformers by a triangular plane tessellation of the macrocycle

    NASA Astrophysics Data System (ADS)

    Khalili, Pegah; Barnett, Christopher B.; Naidoo, Kevin J.

    2013-05-01

    Cyclic conformational coordinates are essential for the distinction of molecular ring conformers as the use of Cremer-Pople coordinates have illustrated for five- and six-membered rings. Here, by tessellating medium rings into triangular planes and using the relative angles made between triangular planes we are able to assign macrocyclic pucker conformations into canonical pucker conformers such as chairs, boats, etc. We show that the definition is straightforward compared with other methods popularly used for small rings and that it is computationally simple to implement for complex macrocyclic rings. These cyclic conformational coordinates directly couple to the motion of individual nodes of a ring. Therefore, they are useful for correlating the physical properties of macrocycles with their ring pucker and measuring the dynamic ring conformational behavior. We illustrate the triangular tessellation, assignment, and pucker analysis on 7- and 8-membered rings. Sets of canonical states are given for cycloheptane and cyclooctane that have been previously experimentally analysed.

  8. Rotational spectra of bicyclic decanes: the trans conformation of (-)-lupinine.

    PubMed

    Jahn, Michaela K; Dewald, David; Vallejo-López, Montserrat; Cocinero, Emilio J; Lesarri, Alberto; Grabow, Jens-Uwe

    2013-12-19

    The conformational and structural properties of the bicyclic quinolizidine alkaloid (-)-lupinine have been investigated in a supersonic jet expansion using microwave spectroscopy. The rotational spectrum is consistent with a single dominant trans conformation within a double-chair skeleton, which is stabilized by more than 10.4 kJ mol(-1) with respect to other conformations. In the isolated conditions of the jet, the hydroxy methyl side chain of the molecule locks in to form an intramolecular O-H···N hydrogen bond to the electron lone pair at the nitrogen atom. Accurate rotational constants, centrifugal distortion corrections, and (14)N nuclear quadrupole coupling parameters are reported and compared to ab initio (MP2) and DFT (M06-2X) calculations. The stability of lupinine is further compared computationally with epilupinine and decaline in order to gauge the influence of intramolecular hydrogen bonding, absent in these molecules. PMID:24028578

  9. Pyranose sulfamates: conformation and hydrogen bonding

    NASA Astrophysics Data System (ADS)

    Kubicki, Maciej; Codding, Penelope W.; Litster, Stephen A.; Szkaradziñska, Maria B.; Bassyouni, Hanan A. R.

    1999-01-01

    The crystal structure of a new anticonvulsant drug, topiramate — 2,3:4,5-bis- O-(1-methylethylidene)- β-D-fructopyranose sulfamate ( 1), together with those of three similar but biologically almost inactive sugar sulfamates: 4,5- O-cyclohexylidene-2,3- O-(1-methyl-ethylidene)- β-D-fructopyranose sulfamate ( 2), 2,3:- O-(1-methylethylidene)- β-D-fructo-pyranose sulfamate ( 3), and 1,2:3,4-bis- O-(1-methylethylidene)- α-D-galactopyranose sulfamate ( 4), have been determined by X-rays. The pyranose rings adopt distorted twist-boat 2S O conformations as a result of flattening of the chair conformation, observed in free pyranoses, by the fused five-membered ring(s). In 3 an unfavourable gauche-trans conformation about C1-C2 bond is observed. The active compound, topiramate ( 1), shows, in comparison with the other three compounds, a different disposition of nitrogen and oxygen atoms from the sulfamate group with respect to the O1-S1 bond. As a result, the nitrogen atom in 1 is ca. 1 Å farther from the O6 pyranose ring oxygen atom than in the other three compounds. This difference describes the mutual disposition of the hydrophilic and hydrophobic parts of the molecule, and can be related to the difference in biological activity. In all compounds, hydrogen bonds connect molecules into three-dimensional networks; simple chains and more complicated rings are found and described using the graph set notation.

  10. Fake conformal symmetry in conformal cosmological models

    NASA Astrophysics Data System (ADS)

    Jackiw, R.; Pi, So-Young

    2015-03-01

    We examine the local conformal invariance (Weyl invariance) in tensor-scalar theories used in recently proposed conformal cosmological models. We show that the Noether currents associated with Weyl invariance in these theories vanish. We assert that the corresponding Weyl symmetry does not have any dynamical role.

  11. American style or Turkish chair: the triumph of bodily comfort.

    PubMed

    Çevik, Gülen

    2010-01-01

    This article investigates the reciprocal influence of Ottoman Turkish and American interiors in the development of seating furniture. Seating furniture is unique because it involves a direct and physical interaction between the piece of furniture and the body, while at the same time it is part of a public space where social interactions occur. I will argue that the interactions between the Ottoman Turks and Americans are reflected in the way these traditions modified their seating furniture as they sought to mediate cultural, political and social differences between them. The concept of bodily comfort will serve as a common thread in understanding the origin of the expression "American style" (Amerikan stili or Amerikan tarzı) in modern Turkish language, the "Turkish chairs" in Victorian America in the late nineteenth century and the English language use of words such as sofa, ottoman and divan. PMID:21114093

  12. Human Vestibular Function, Rotating Litter Chair - Skylab Experiment M131

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This 1970 photograph shows the Rotating Litter Chair, a major component of Skylab's Human Vestibular Function experiment (M131). The experiment was a set of medical studies designed to determine the effect of long-duration space missions on astronauts' coordination abilities. The M131 experiment tested the astronauts susceptibility to motion sickness in the Skylab environment, acquired data fundamental to an understanding of the functions of human gravity reception under prolonged absence of gravity, and tested for changes in the sensitivity of the semicircular canals. Data from this experiment was collected before, during, and after flight. The Marshall Space Flight Center had program management responsibility for the development of Skylab hardware and experiments.

  13. Airline Chair-rest Deconditioning: Induction of Immobilization Thromboemboli?

    NASA Technical Reports Server (NTRS)

    Greenleaf, J. E.; Rehrer, N. J.; Mohler, S. R.; Quach, D. T.; Evans, D. G.; Dalton, Bonnie P. (Technical Monitor)

    2002-01-01

    Air passenger miles will likely double by year 2020. The altered and restrictive environment in an airliner cabin can influence hematological homeostasis in passengers and crew. Flight-related deep various thromboemboli (DVT) have been associated with at least 577 deaths on 42 of 120 airlines from 1977 to 1984 (25 deaths/million departures), whereas many such cases go unreported. However, there are four major factors that could influence formation of possible flight-induced DVT: sleeping accomodations (via sitting immobilization), travelers' medical history (via tissue injury), cabin environmental factors (via lower partial pressure of oxygen and lower relative humidity), and the more encompassing chair-rest deconditioning (C-RD) syndrome. There is ample evidence that recent injury and surgery (especially in deconditioned hospitalized patients) facilitate thrombophlebitis and formation of DVT that may be exacerbated by the immobilization of prolonged air travel. In the healthy flying population immobilization factors associated with prolonged (> 5 hr) C-RID such as total body dehydration, hypovolemia and increased blood viscosity, and reduced various blood flow (pooling) in the legs may facilitate formation of DVT. However, data from at least four case-controlled epidemiological studies did not confirm a direct causative relationship between air travel and DART, but factors such as history of vascular thromboemboli, various insufficiency, chronic heart failure, obesity, immobile standing position, more than 3 pregnancies, infectious disease, long-distance travel, muscular trauma and violent physical effort were significantly more frequent in DVT patients than in controls. Thus, there is no clear, direct evidence yet that prolonged sitting in airliner seats, or prolonged experimental chair-rest- or bed- rest-deconditioning treatments cause deep various thromboemboli in healthy people.

  14. Airline chair-rest deconditioning: induction of immobilisation thromboemboli?

    NASA Technical Reports Server (NTRS)

    Greenleaf, John E.; Rehrer, Nancy J.; Mohler, Stanley R.; Quach, David T.; Evans, David G.

    2004-01-01

    Air passenger miles will likely double by year 2020. The altered and restrictive environment in an airliner cabin can influence haematological homeostasis in passengers and crew. Flight-related deep venous thromboemboli (DVT) have been associated with at least 577 deaths on 42 of 120 airlines from 1977 to 1984 (25 deaths/million departures), whereas many such cases go unreported. However, there are four major factors that could influence formation of possible flight-induced DVT: sleeping accommodations (via sitting immobilisation); travellers' medical history (via tissue injury); cabin environmental factors (via lower partial pressure of oxygen and lower relative humidity); and the more encompassing chair-rest deconditioning (C-RD) syndrome. There is ample evidence that recent injury and surgery (especially in deconditioned hospitalised patients) facilitate thrombophlebitis and formation of DVT that may be exacerbated by the immobilisation of prolonged air travel.In the healthy flying population, immobilisation factors associated with prolonged (>5 hours) C-RD such as total body dehydration, hypovolaemia and increased blood viscosity, and reduced venous blood flow (pooling) in the legs may facilitate formation of DVT. However, data from at least four case-controlled epidemiological studies did not confirm a direct causative relationship between air travel and DVT, but factors such as a history of vascular thromboemboli, venous insufficiency, chronic heart failure, obesity, immobile standing position, more than three pregnancies, infectious disease, long-distance travel, muscular trauma and violent physical effort were significantly more frequent in DVT patients than in controls. Thus, there is no clear, direct evidence yet that prolonged sitting in airliner seats, or prolonged experimental chair-rest or bed-rest deconditioning treatments cause DVT in healthy people.

  15. Report of the 10(th) Asia-Pacific Federation of Societies for Surgery of the Hand Congress (Organising Chair and Scientific Chair).

    PubMed

    A, Roohi Sharifah; Abdullah, Shalimar

    2016-10-01

    A report on the 10(th) Asia-Pacific Federation of Societies for the Surgery of the Hand and 6(th) Asia-Pacific Federation of Societies for Hand Therapists is submitted detailing the numbers of attendees participating, papers presented and support received as well the some of the challenges faced and how best to overcome them from the local conference chair and scientific chair point of view. PMID:27595972

  16. A Factor-Analytic Investigation of Role Types and Profiles of Higher Education Department Chairs.

    ERIC Educational Resources Information Center

    Carroll, James B.; Gmelch, Walter H.

    This paper reports on a study that investigated the role, attitudes, and behaviors of department chairs in higher education. Specifically, the study investigated four objectives: (1) to examine role factors of effective chair performance; (2) to assess the impact of antecedent variables such as individual characteristics (gender, marital status,…

  17. Preparing Department Chairs for Their Leadership Roles. New Directions for Community Colleges, Number 105.

    ERIC Educational Resources Information Center

    Gillet-Karam, Rosemary, Ed.

    1999-01-01

    This issue focuses on preparing department chairs for their leadership roles. It presents qualities that experienced chairs cite as being crucial to success, and asserts the need to develop formal training programs for people newly appointed to these positions. Articles include: (1) "Midlevel Management in the Community College: A Rose Garden?"…

  18. Stress Factors, Role Conflict, and Role Ambiguity for Academic Department Chairs.

    ERIC Educational Resources Information Center

    Burns, John S.; Gmelch, Walter H.

    This investigation examined the dimensional sources and perceptions of occupational stress experienced by department chairs in institutions of higher education, and the influence of professional independent variables associated with these stressors. Surveys were mailed to 800 randomly selected department chairs at 100 institutions (523 surveys…

  19. Influence of Web-Based Distance Education on the Academic Department Chair Role

    ERIC Educational Resources Information Center

    Franklin, Kathy K.; Hart, Jan K.

    2006-01-01

    The purpose of this study was to examine academic department chair perceptions about the future influence of web-based distance education on departmental operations and their changing role as academic leader. Using a rating, modified-policy Delphi method, the researcher worked with 22 department chairs employed at public, urban universities in the…

  20. Leadership Experiences and Characteristics of Chairs of Academic Departments of Psychiatry

    ERIC Educational Resources Information Center

    Keith, Samuel J.; Buckley, Peter F.

    2011-01-01

    Objective: Effective leadership in academic medicine requires a broad constellation of skills, experiences, and core values. The authors sought to describe and define these. Method: The authors conducted a web-based survey among 132 Chairs of North American departments of psychiatry. Results: Eighty-five Chairs (64%) responded to the survey, the…

  1. 20 CFR 661.320 - Who must chair a Local Board?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Who must chair a Local Board? 661.320 Section... Governance Provisions § 661.320 Who must chair a Local Board? The Local Board must elect a chairperson from among the business representatives on the board. (WIA sec. 117(b)(5).)...

  2. The Community College Department Chair and Curriculum Leadership: Managing Learning and Learning to Manage

    ERIC Educational Resources Information Center

    Sweeney, Kathleen Jennings

    2012-01-01

    Dwindling resources, the challenges of providing postsecondary remedial education, and an environment that emphasizes outcomes assessment are realities that confront the community college department chair. The role of the department chair is particularly challenging in the community college context due to accountability pressures, fiscal…

  3. Dimensions of Leadership among Community College Health Career Program Department Chairs and Implications for Leadership Development

    ERIC Educational Resources Information Center

    Platz-Wiechert, Lynn Marie

    2010-01-01

    Given the growth in community colleges, the projected need for health career workers, and the central position of the department chair in higher education, this study explored dimensions of leadership as identified by health career department chairs in five Illinois community colleges. Areas of study included: (a) professional profiles of health…

  4. The Chair and the New President: Getting the First Months Right

    ERIC Educational Resources Information Center

    Riggs, Janet Morgan; Duelks, Robert

    2012-01-01

    Gettysburg College President Janet Morgan Riggs and Board Chair Robert N. Duelks are both members of the Gettysburg class of 1977, but did not know each other as students. As a member of the college's board of trustees, Duelks chaired the presidential search committee that selected Riggs as Gettysburg's 14th president in 2009. Then, one year after…

  5. The Body Language Behaviours of the Chairs of the Disputes According to the Disputants

    ERIC Educational Resources Information Center

    Caliskan, Nihat

    2009-01-01

    The perception form of the body language behaviours of the session chairs by disputants affects the efficiency of the process. Therefore, it is important to determine the effects of the mimic, gesture, physical appearance and tonality and accent of the chairs on disputants. That research was conducted to clarify how the disputants perceive the…

  6. Cultivating Possibilities: Prospective Department Chair Professional Development and Why It Matters

    ERIC Educational Resources Information Center

    Wolverton, Mimi; Ackerman, Robert

    2006-01-01

    Faculty who are selected to be academic department chairs generally lack leadership preparation and have little understanding of the demands of the position. Good experiences as a faculty member do not necessarily translate to being a good department chair. As strategic planning becomes increasingly essential to the well being of colleges and…

  7. King among Kings: Understanding the Role and Responsibilities of the Department Chair in Higher Education

    ERIC Educational Resources Information Center

    Berdrow, Iris

    2010-01-01

    The role and responsibilities of the chair of an academic department in higher education is considered from the perspective of both actor and agent, within the context of the institution being served and the department being represented. The intent of this article is to further research on the role of department chair by analyzing it in the…

  8. 21 CFR 878.4950 - Manual operating table and accessories and manual operating chair and accessories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Manual operating table and accessories and manual... Surgical Devices § 878.4950 Manual operating table and accessories and manual operating chair and accessories. (a) Identification. A manual operating table and accessories and a manual operating chair...

  9. Roles, Responsibilities, Challenges, and Rewards: The Lived Experience of ESL Department Chairs in Community Colleges

    ERIC Educational Resources Information Center

    Lam, Chin

    2014-01-01

    This study addresses the lived experience of ESL department chairs in California community colleges. It adds to existing literature that aims to support these individuals who are serving in critical roles in institutions of higher education. Using phenomenological methods, four ESL department chairs were interviewed to explore their journeys…

  10. Chair Perceptions of Trust between Mentor and Mentee in Online Doctoral Dissertation Mentoring

    ERIC Educational Resources Information Center

    Rademaker, Linnea L.; Duffy, Jennifer O'Connor; Wetzler, Elizabeth; Zaikina-Montgomery, Helen

    2016-01-01

    We explored online dissertation chairs' perceptions of trust in the mentor-mentee relationship, as trust was identified as a crucial factor in the success of doctoral students. Through the implementation of a multiple-case study, and a qualitative, online questionnaire, and through qualitative data analysis, we discovered 16 chairs' perceptions of…

  11. 76 FR 20651 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ... Environmental Management Site-Specific Advisory Board Chairs (76 FR 17118). This notice announces the... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of cancellation of open meeting. SUMMARY: On March 28, 2011, in FR Doc. 2011-7243, on page 17118, the...

  12. DOE Chair of Excellence Professorship in Environmental Disciplines

    SciTech Connect

    Shoou-Yuh Chang

    2013-01-31

    The United States (US) nuclear weapons program during the Cold War left a legacy of radioactive, hazardous, chemical wastes and facilities that may seriously harm the environment and people even today. Widespread public concern about the environmental pollution has created an extraordinary demand for the treatment and disposal of wastes in a manner to protect the public health and safety. The pollution abatement and environmental protection require an understanding of technical, regulatory, economic, permitting, institutional, and public policy issues. Scientists and engineers have a major role in this national effort to clean our environment, especially in developing alternative solutions and evaluation criteria and designing the necessary facilities to implement the solutions. The objective of the DOE Chair of Excellence project is to develop a high quality educational and research program in environmental engineering at North Carolina A&T State University (A&T). This project aims to increase the number of graduate and undergraduate students trained in environmental areas while developing a faculty concentrated in environmental education and research. Although A&T had a well developed environmental program prior to the Massie Chair grant, A&T's goal is to become a model of excellence in environmental engineering through the program's support. The program will provide a catalyst to enhance collaboration of faculty and students among various engineering departments to work together in a focus research area. The collaboration will be expanded to other programs at A&T. The past research focus areas include: hazardous and radioactive waste treatment and disposal fate and transport of hazardous chemicals in the environment innovative technologies for hazardous waste site remediation pollution prevention Starting from 2005, the new research focus was in the improvement of accuracy for radioactive contaminant transport models by ensemble based data assimilation. The

  13. An allolactose trapped at the lacZ β-galactosidase active site with its galactosyl moiety in a (4)H3 conformation provides insights into the formation, conformation, and stabilization of the transition state.

    PubMed

    Wheatley, Robert W; Huber, Reuben E

    2015-12-01

    When lactose was incubated with G794A-β-galactosidase (a variant with a "closed" active site loop that binds transition state analogs well) an allolactose was trapped with its Gal moiety in a (4)H3 conformation, similar to the oxocarbenium ion-like conformation expected of the transition state. The numerous interactions formed between the (4)H3 structure and β-galactosidase indicate that this structure is representative of the transition state. This conformation is also very similar to that of d-galactono-1,5-lactone, a good transition state analog. Evidence indicates that substrates take up the (4)H3 conformation during migration from the shallow to the deep mode. Steric forces utilizing His418 and other residues are important for positioning the O1 leaving group into a quasi-axial position. An electrostatic interaction between the O5 of the distorted Gal and Tyr503 as well as C-H-π bonds with Trp568 are also significant. Computational studies of the energy of sugar ring distortion show that the β-galactosidase reaction itinerary is driven by energetic considerations in utilization of a (4)H3 transition state with a novel (4)C1-(4)H3-(4)C1 conformation itinerary. To our knowledge, this is the first X-ray crystallographic structural demonstration that the transition state of a natural substrate of a glycosidase has a (4)H3 conformation. PMID:26291713

  14. Low Profile, High Impact: Four Case Studies of High School Department Chairs Whose Transactions "Transform" Teachers and Administrators.

    ERIC Educational Resources Information Center

    Wettersten, Jill A.

    This paper explores the leadership strategies of four exemplary high school department chairs. It develops a model based on social-exchange theory to show how chairs, as middle managers, must satisfy the expectations of both teachers and administrators. Data were derived from a case study of department chairs identified as exemplary in four…

  15. 75 FR 44767 - Folding Metal Tables and Chairs From the People's Republic of China: Initiation of New Shipper...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    ... Chairs From the People's Republic of China, 67 FR 43277 (June 27, 2002). On June 30, 2010, we received a... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of China... metal tables and chairs (``FMTCs'') from the People's Republic of China (``PRC''), received on June...

  16. Voices of Women in the Field: The Top 10 Things We Learned about Being a Department Chair

    ERIC Educational Resources Information Center

    Danielson, Lana; Schulte, Laura

    2007-01-01

    This article documents the top 10 things we learned in our transition from being a faculty member to becoming a department chair. We were recruited as department chairs in the same year and quickly recognized each other as administrative colleagues. During our "internship" in the chair position we frequently identified lessons we were learning,…

  17. The Department Chair: Professional Development and Role Conflict. AAHE-ERIC/Higher Education Research Report No. 10, 1982.

    ERIC Educational Resources Information Center

    Booth, David B.

    The role of the department chair as the interface between faculty and administration is considered, along with the selection, orientation, socialization, and evaluation of the chair. Attention is directed to constraints under which chairs work that are beyond their control and the way that the resulting conflict, overload, and ambiguity impede…

  18. What does your chair know about your stress level?

    PubMed

    Arnrich, Bert; Setz, Cornelia; La Marca, Roberto; Tröster, Gerhard; Ehlert, Ulrike

    2010-03-01

    The inferred cost of work-related stress call for early prevention strategies. In this, we see a new opportunity for affective and pervasive computing by detecting early warning signs. This paper goes one step toward this goal. A collective of 33 subjects underwent a laboratory stress intervention, while a set of physiological signals was collected. In this paper, we investigate whether affective information related to stress can be found in the posture channel during office work. Following more recent work in this field, we directly associate features that are derived from the pressure distribution on a chair with affective states. We found that nervous subjects reveal higher variance of movements under stress. Furthermore, we show that a person-independent discrimination of stress from cognitive load is feasible when using pressure data only. A supervised variant of a self-organizing map, which is able to adapt to different patterns of stress responses, reaches an overall accuracy of 73.75% with unknown subjects. PMID:19887325

  19. A chair with a platform setup to measure the forces under each thigh when sitting, rising from a chair and sitting down.

    PubMed

    Nadeau, S; Desjardins, P; Brière, A; Roy, G; Gravel, D

    2008-03-01

    This paper describes the design, technical characteristics and first results of an adjustable instrumented chair with a sitting surface that records the forces under each thigh. The seat includes a force platform assembly suitable for measuring the magnitude, position and direction of the force applied to each thigh while sitting or rising from the chair. The natural frequency of the chair fixed to the floor was found to be 14.0 +/- 2 Hz with an estimated damping of xi = 0.20. Static tests showed that the maximal errors were 2% of the full-scale output (726 N vertically, 164 N horizontally) for both vertical and horizontal forces. The root mean square error of the center of pressure location was estimated as 5 mm. Preliminary data on the net joint moment at the hips of one healthy subject computed with and without consideration for the forces under the thighs revealed significant amplitude differences. In conclusion, the results indicate that the characteristics of the instrumented chair are acceptable and the chair can be used to assess the biomechanics of sitting and sit-to-stand and stand-to-sit tasks in various subject populations. PMID:18193467

  20. SU-C-19A-05: Treatment Chairs for Modern Radiation Therapy Treatments

    SciTech Connect

    Court, L; Fullen, D; Tharp, K; Palmer, J; Ungchusri, G; Reyes, L; Tong, T; Nguyen, S; Phillips, T; Balter, P

    2014-06-15

    Purpose: Treating patients in a seated position has potential advantages including improved comfort, increased lung volume, and reduced respiratory motion. We compared chair designs for head and neck, thoracic and breast patients for use with either IGRT linacs or a proposed low-cost fixed horizontal beam-line machine. Methods: Three treatment chairs were designed and constructed. Two of the chairs are based on a massage-chair, with the patient angled slightly forwards and knee rests used to minimize intra-fraction slouch. The third chair design is more conventional; the patient is angled backwards, with indexed positioning devices and the ability to attach thermoplastic masks. Patient geometries, including PTV location and patient sizes, were extracted from 137 CTs of past patients were used to model the probability of collision between the patient and the linac for various seated positions. All chairs were designed around the weight limits for couches on our linacs. At the time of writing we have just received IRB approval for imaging studies to evaluate comfort, and intra- and interfraction reproducibility. Results: The geometric analysis showed that head and neck patients and thoracic patients could be treated without collision. However, there is very limited space between the patient and the treatment/imaging devices, so careful design of the chair is essential. The position of the treatment target and extended arm positioning means that this is a particular concern for thoracic and breast patients. This was demonstrated for one of the prototype chairs designed for breast treatment where the arm holders would collide with the kV detector. The extra clearance of a dedicated fixed-beam linac would overcome these difficulties. Intra- and inter-fraction reproducibility results will be presented at the meeting. Conclusion: To take advantage of the clinical advantages of seated treatments, appropriate treatment chairs are needed. A dedicate fixed-beam linac may

  1. Design of the advanced commode-shower chair for spinal cord-injured individuals.

    PubMed

    Malassigné, P; Nelson, A L; Cors, M W; Amerson, T L

    2000-01-01

    The purpose of this development project was to design a new commode-shower chair that can be safely used by individuals with spinal cord injuries (SCI) and their caregivers. The need for this new design was consumer-driven. Patients and caregivers identified the following fatal flaws in the commode-shower chairs used in Spinal Cord Injury (SCI) centers: 1) risk for patient falls during transfers, propelling, and while leaning over for showering; 2) risk for pressure ulcers due to inadequate padding and seat positioning for lengthy bowel care regimes; 3) inadequate caregiver access to the perianal area of the patient to perform bowel care procedures; and, 4) wheel-related inability to properly position the chair directly over the toilet. The new, self-propelled chair addresses each of these concerns. Lockable, swing-away, pivoting armrests and improved, lever-activated brakes were designed to facilitate safe transfers. An innovative foot-lift was invented to facilitate washing of feet. Larger handrims were designed to aid in propulsion in wet environments. To prevent pressure ulcers, a chair frame and padding combination was designed to facilitate a seating position that optimally distributes body weight to prevent the development of pressure ulcers in the sacral and ischial areas. To address the common risk of heel ulcers, footrests, featuring edgeless, rounded heel cups, were designed. A new tubular chair frame, a new seat and smaller wheels were designed to enhance caregiver access and ensure proper chair positioning over the toilet. Following its successful clinical evaluation at the Milwaukee and Tampa VA Medical SCI Centers, the Advanced commode-shower chair is being patented by the Department of Veterans Affairs (VA). The VA has partnered with Everest & Jennings, to make this chair available commercially. PMID:10917269

  2. Restraint chair with rowing-like movement for exposing exercising nonhuman primates to microwave irradiation

    SciTech Connect

    Knepton, J.; Ezell, C.; de Lorge, J.

    1983-04-20

    Design and construction of a Styrofoam exercise restraint chair is described for use with rhesus monkeys exposed to microwaves. Monkeys usually learn the rowing-like motion of the device within five 1-hour conditioning sessions. Radiation intensity measure of the chair and an example animal experiment demonstrated the chair's suitability for bioelectromagnetic studies. Results of a series of base-line behavioral sessions demonstrated concomitant exercise work load effects on colonic temperature, heart rate, correct response rate, and post-reinforcement pause time. With additional instrumentation, detection of minute disturbances of integrated psychological and physiological mechanisms by unusual environmental factors may be possible.

  3. 5-Oxocyclooctanecarboxylic acid: hydrogen-bonding pattern and conformational disorder in a medium-ring varepsilon-keto acid

    PubMed

    Lalancette; Brunskill; Thompson

    2000-10-01

    Molecules of the title compound, C(9)H(14)O(3), adopt a chiral 'boat-chair' conformation, in which the carboxyl group avoids potential cross-ring ketone interactions by an outward 'equatorial' orientation. The asymmetric unit contains two such molecules, one conformationally fixed without disorder, (I), and the other, (I'), extensively disordered, both in the bond lengths and angles of the carboxyl and by a coupled 'up-down' conformational disordering [ratio of 60:40 (1)] of the remote ends of the boat-chair system. Each molecule in the asymmetric unit forms a centrosymmetric hydrogen-bonded carboxyl dimer with a second molecule of its own type. For (I), O.O = 2.658 (3) A and O-H.O = 174 degrees. For (I'), O.O = 2.653 (3) A and O-H.O = 165 degrees. A number of intermolecular C=O.H-C close contacts are found. PMID:11025318

  4. Galilean conformal electrodynamics

    NASA Astrophysics Data System (ADS)

    Bagchi, Arjun; Basu, Rudranil; Mehra, Aditya

    2014-11-01

    Maxwell's Electrodynamics admits two distinct Galilean limits called the Electric and Magnetic limits. We show that the equations of motion in both these limits are invariant under the Galilean Conformal Algebra in D = 4, thereby exhibiting non-relativistic conformal symmetries. Remarkably, the symmetries are infinite dimensional and thus Galilean Electrodynamics give us the first example of an infinitely extended Galilean Conformal Field Theory in D > 2. We examine details of the theory by looking at purely non-relativistic conformal methods and also use input from the limit of the relativistic theory.

  5. Conformational analysis of menthol diastereomers by NMR and DFT computation

    NASA Astrophysics Data System (ADS)

    Härtner, Julia; Reinscheid, Uwe M.

    2008-01-01

    Correlations between experimental and calculated 13C chemical shifts were performed with the series of all menthol diastereomers. In this way it could be shown that identification problems with newly isolated natural products can be solved. Starting from simulated, low energy conformers of menthol, neomenthol, isomenthol, and neoisomenthol the 13C chemical shifts were obtained using DFT calculations [functional: B3LYP, basis set: 6-31G(d,p)]. Due to differences in chemical shifts, the prochiral methyl groups of the isopropyl substituent of menthol could be differentiated using the correlations between experimental and calculated values. A conformational scan of the dihedral angle of the isopropyl group allowed the determination of the dominating rotamers of menthol (+68.4°) and neomenthol (+172.5°) using 13C chemical shifts. The results were supported by energy calculations, 1JCH and 3JHH measurements. The correlations and 3JHH measurements for isomenthol indicate conformational averaging impeding the determination of the isopropyl group rotamer. For neoisomenthol, MD simulations showed two chair conformations. However, in contrast to calculated energies and correlations between theoretical and experimental 13C chemical shifts, the measured 3JH3H2 coupling of 6.3 Hz indicates an equally populated equilibrium of both conformers.

  6. Probing of different conformations of piperazine using Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    SenGupta, Sumana; Maiti, Nandita; Chadha, Ridhima; Kapoor, Sudhir

    2014-06-01

    Piperazine exists in a number of energetically close structural conformations, and here, we investigated the dependence of their relative abundance on the surrounding conditions by using Raman and SERS spectroscopy in pure solid, aqueous solution and Ag hydrosol. The experimental results were interpreted by DFT calculations using B3LYP functional with aug-cc-pvdz/LANL2DZ basis sets. In the chair form of piperazine, which is more stable than the skewed boat by ∼8 kcal mol-1, the two N-H bonds can remain equatorial or axial, leading to three different conformations, eq-eq, eq-ax and ax-ax. The calculated Raman spectrum of the lowest energy eq-eq conformation corresponds well with the experimental spectrum in pure solid, indicating eq-eq to be predominant. But, the contribution of the eq-ax conformation was found to be maximum in aqueous solution. The SERS spectrum revealed that eq-ax conformation was preferably adopted as piperazine was adsorbed vertically through its axial N-atom over silver nanoparticle surface.

  7. Samuel P. Massie Chair of Excellence in Environmental Disciplines

    SciTech Connect

    Adeyiga, Adeyinka A.

    2014-12-17

    The establishment of the DOE-EM Dr. Samuel P. Massie Chair of Excellence provides an excellent opportunity for Hampton University to be involved in key environmental issues in the 21st Century. The main areas of focus are on: 1. Coal gasification with respect to pollution prevention and reduction. 2. Solid waste treatment through bioremediation technology and 3. Industrial wastewater treatment Synthesizing ion catalysts suitable for use in slurry bubble column reaction was carried out. Construction of an autoclave continuous stirred tank reactor has been completed. At the initial stage of the development of this program, work was conducted in the area of formic acid recovery from waste streams, which yielded useful results. We also succeeded in the removal of priority metal ions such as cadmium, chromium, copper, lead, mercury, nickel, silver, thallium, zinc, etc., from industrial and municipal wastewater by using natural wastes. The process uses tree leaves to adsorb the metal ions in the wastewater. The ultimate goal is to develop inexpensive, highly available, effective metal ion adsorbents from natural wastes as an alternative to existing commercial adsorbents, and also to explain the possible adsorption mechanism that is taking place. This technology uses natural wastes to eliminate other wastes. Obviously, there are several advantages: (1) the negative impact on environment is eliminated, (2) the complicated regeneration step is not needed, and (3) the procedure saves money and energy. Twelve different types of leaves have been tested with lead, zinc, and nickel. The study mechanism showed that the leaf tannin is an active ingredient in the adsorption of metal ions. The ion-exchange mechanism controlled the adsorption process.

  8. The Green Chair: A Motivation for Teenagers To Replace Aggressive Behavior with Words.

    ERIC Educational Resources Information Center

    Lipetz, Laura

    2001-01-01

    Using a technique designed to channel students' aggressive behavior into constructive energy, students who intend to act out sit in a chair and say anything they want. This therapeutic talk reduces disruptive behavior. (SK)

  9. A President Interprets the Roles and Powers of the Ideal Chair.

    ERIC Educational Resources Information Center

    Dedmon, Donald N.

    1985-01-01

    Considers the department chair crucial to the welfare of the university, responsible for housekeeping functions (scheduling, planning, etc.), recruiting faculty and students, and assuming advisory/leadership roles in the campus community. (PD)

  10. Effect of beach chair position on bispectral index values during arthroscopic shoulder surgery

    PubMed Central

    Lee, Sang Wook; Choi, Soo Eun; Han, Jin Hee; Kang, Wha Ja; Choi, Young Kyoo

    2014-01-01

    Background Bispectral index (BIS) monitoring reduces the cases of intraoperative awareness. Several factors can alter BIS readings without affecting the depth of anesthesia. We conducted a study to assess the impact of beach chair position (sitting position) on BIS readings. Methods General anesthesia was administered to 30 patients undergoing arthroscopic shoulder surgery. Patients were kept in neutral position (supine) for 10 minutes and BIS readings, mean arterial blood pressure, heart rate, end-tidal carbon dioxide, and end-tidal sevoflurane were recorded. Patients were then shifted to beach chair position. After 15 minutes, data were recorded. Results A significant decrease in BIS values (P < 0.01) associated with a position change from neutral position to beach chair position was evident. Conclusions BIS values are significantly decreased in the beach chair position compared with the neutral position and might affect interpretation of the depth of anesthesia. PMID:25368780

  11. Comparison of seat pressures on three bowel care/shower chairs in spinal cord injury.

    PubMed

    Nelson, A L; Malassigné, P; Murray, J

    1994-12-01

    Pressure, positioning, and postural support are critical aspects in the design of a new bowel care/shower chair for persons with spinal cord injuries (SCI). The purpose of this evaluation was to evaluate seating pressures on three existing bowel care/shower chairs commonly used by persons with spinal cord injuries. A pressure mapping device, the Force Sensing Array, was used to measure seat pressure, position and postural support. Three seated subjects with spinal cord injuries were evaluated on each of the following three bowel care/shower chairs: Lumex, TRAUM-AID and E&J. The results of this evaluation will be briefly presented. This study is part of a larger study to design a bowel care/shower chair that uniquely meets the needs of persons with spinal cord injury. PMID:7777842

  12. The Trial: A Parable of a Department Chair before the Law of the Budget.

    ERIC Educational Resources Information Center

    Beja, Morris

    1994-01-01

    Discusses the seemingly contradictory nature of chairing an English department by highlighting the opposing impulses faced, especially as related to funding. Presents the situation in the form of a parable similar to a work by Franz Kafka. (HB)

  13. Access to the Heads and Chairs Program expands beyond AGU Fall Meeting

    NASA Astrophysics Data System (ADS)

    Asher, Pranoti M.; Keane, Christopher M.

    2012-09-01

    The AGU Education and Public Outreach department is pleased to announce a new collaboration with the American Geosciences Institute (AGI) for AGU's existing Heads and Chairs Program. This collaboration developed from a mutual interest in supporting the higher education departments of Earth and space sciences, as well as a desire to combine activities and resources toward strengthening that support. Through this partnership, AGI's Workforce Program and AGU's education staff are hosting hour-long webinars on various topics each month to engage department heads and chairs in discussions that will help them share, learn, and apply new ideas to their own programs. The ultimate goal is to provide opportunities for open dialogue beyond the annual Heads and Chairs workshops held at the AGU Fall Meeting each year, as well as to support those heads and chairs who are unable to attend Fall Meeting.

  14. Conformal bootstrap in embedding space

    NASA Astrophysics Data System (ADS)

    Fortin, Jean-François; Skiba, Witold

    2016-05-01

    It is shown how to obtain conformal blocks from embedding space with the help of the operator product expansion. The minimal conformal block originates from scalar exchange in a four-point correlation function of four scalars. All remaining conformal blocks are simple derivatives of the minimal conformal block. With the help of the orthogonality properties of the conformal blocks, the analytic conformal bootstrap can be implemented directly in embedding space, leading to a Jacobi-like definition of conformal field theories.

  15. Modeling and experiment reveal an unexpected stereoelectronic effect on conformation and scalar couplings of alpha-aminoorganostannanes, with possible relevance to the tin-lithium exchange reaction.

    PubMed

    Santiago, Marcelina; Low, Eddy; Chambournier, Gilles; Gawley, Robert E

    2003-10-31

    The solution conformation of N-methyl-2-(tributylstannyl)piperidines has been determined through the use of vicinal 119Sn-13C coupling constants, revealing a conformational distortion caused by an unexpected stereoelectronic effect in some cases. Specifically, the "equatorial" conformer is distorted into a half-chair, in which the nitrogen lone pair eclipses the C-Sn bond. This distortion, which "costs" approximately 1 kcal/mol, correlates with a conformational dependence of geminal 119Sn-15N couplings and a possible correlation with reactivity in the tin-lithium exchange reaction. PMID:14575474

  16. Managing osteoarthritis: comparisons of chair yoga, Reiki, and education (pilot study).

    PubMed

    Park, Juyoung; McCaffrey, Ruth; Dunn, Dorothy; Goodman, Rhonda

    2011-01-01

    The aim of this pilot study was to determine whether chair yoga and Reiki affect pain, depressive mood, and physical function compared with an educational program for older adults with osteoarthritis. Findings showed significant relationships only between physical function and chair yoga. In focus group interviews, participants expressed feelings of improved health and well-being after the yoga intervention. The major limitation of this study was the small sample size. PMID:22015342

  17. Conformations of Substituted Ethanes.

    ERIC Educational Resources Information Center

    Kingsbury, Charles A.

    1979-01-01

    Reviews state-of-the-art of conformational analysis and factors which affect it. Emphasizes sp-3 hybridized acrylic molecules. Provides examples on the importance of certain factors in determining conformation. Purpose, is to provide examples for examination questions. (Author/SA)

  18. Effect of Furniture Weight on Carrying, Lifting, and Turning of Chairs and Desks among Elementary School Children

    PubMed Central

    Funatsu, Kyotaro; Xiong, Jinghong; Rosyidi, Cucuk Nur

    2015-01-01

    Rearranging furniture in elementary school classrooms encourages classroom activities. In elementary schools in Indonesia and some other developing countries, usually only one style of furniture is used for all children, and the furniture is heavy and oversized for younger children. This affects their ability to carry it. The objective of this study is to investigate the effects of elementary school furniture weight and children’s age on performance of three carrying tasks (carrying a chair, lifting and turning a chair on a desk, and carrying both a chair and a desk together), from the ergonomics point of view. A total of 42 schoolchildren (ages 6–9; 17 Indonesian, 25 Japanese) participated in this study. Two types of Japanese chairs (Chair A and B, weight: 3.2 kg and 3.9 kg), one type of Indonesian chair (Chair C, weight: 5.0 kg), and two types of desks (height: 58 cm and 68 cm) were used. Indonesian chairs took significantly longer time to carry than the two Japanese chairs, and there was a significant negative relationship between age and task time for Chairs B and C, but not Chair A. Success rates for lifting and turning the chair declined as age decreased and chair weight increased, but were not significantly influenced by desk height. Success rates for carrying a chair and desk together significantly decreased with heavier furniture. Children aged six showed an extremely low success rate in almost all conditions. In conclusion, children’s ability to carry furniture is affected by their age and furniture characteristics, especially weight. In order to encourage classroom activities in elementary school, school furniture should be of appropriate weight. Supervision for younger children is required during classroom furniture arrangement. PMID:26053154

  19. Respiratory chest movement measurement as a chair quality indicator – preliminary observations

    PubMed Central

    Szczygieł, Elżbieta; Zielonka, Katarzyna; Mazur, Tadeusz; Mętel, Sylwia; Golec, Joanna

    2015-01-01

    Regardless of the constantly increasing time man is spending in a sitting position, there is still a lack of objective chair quality assessment criteria. The aim of this paper is to find the answer to whether respiratory chest movement measurements can be a chair quality indicator. The study included 34 participants (mean 34.7 years ± 5.2). Their chest movements were assessed using respiratory inductive plethysmography while sitting on two subsequent chairs. Significant differences in chest movements depending on chair type were observed concerning the breathing duct (upper and lower) and breathing movement amplitude. The amplitude of the upper respiratory track in the first chair was higher (239.4 mV) compared with the second seat (207.3 mV) (p = .018). The analyzed parameters of respiratory chest movement may become a helpful indicator for design and selection of chairs which enable people to both work and relax in the most ergonomic conditions. PMID:26323780

  20. Changes of Musculoskeletal Deformity in Severely Disabled Children Using the Custom Molded Fitting Chair

    PubMed Central

    Kim, Myeong Ok; Lee, Jun Ho; Yu, Ju Young; An, Pil Suk; Hur, Do Hang; Park, Eun Seo

    2013-01-01

    Objective To know the effectiveness of a custom molded fitting chair between pre- and post-chair status through comparison of musculoskeletal indices in severely disabled children. Methods We researched 34 severely disabled patients who had used a custom molded fitting chair continuously for more than a year. There were 27 cerebral palsy patients and 7 patients with other kinds of diseases that affect the brain such as chromosomal disease or metabolic disease. By radiographic studies, Cobb's angle, the femoral neck-shaft angle of the femur, and Reimers migration percentage were measured. The indices are analyzed before and after application. Results The average period of application was 24 months. There was a significant reduction in the angles of femur neck-shaft, 163.4 degree before and 158.2 degree after the use of the chair (p<0.05), and 23 of 34 had demonstrated a reduced angle. Cobb's angle and Reimers migration percentage increased but the difference of pre- and post-chair status was not statistically significant. Seventeen of 33 children showed reduced Cobb's angle. Also, 19 of 37 showed a reduced degree of dislocation of the hip joints. Conclusion In spite of the use of a custom molded fitting chair, a significant improvement did not emerge for musculoskeletal deformity indices in severely disabled children. However, there was no significant aggravation of Cobb's angle or Reimers migration percentage in developing children. Therefore, it is thought be helpful to prevent rapid aggravation of musculoskeletal deformities. PMID:23524955

  1. Investigation of the role of stereoelectronic effects in the conformation of piperidones by NMR spectroscopy and X-ray diffraction.

    PubMed

    Garcias-Morales, Cesar; Ortegón-Reyna, David; Ariza-Castolo, Armando

    2015-01-01

    This paper reports the synthesis of a series of piperidones 1-8 by the Mannich reaction and analysis of their structures and conformations in solution by NMR and mass spectrometry. The six-membered rings in 2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonan-9-ones, compounds 1 and 2, adopt a chair-boat conformation, while those in 2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9-ones, compounds 3-8, adopt a chair-chair conformation because of stereoelectronic effects. These stereoelectronic effects were analyzed by the (1) J C-H coupling constants, which were measured in the (13)C satellites of the (1)H NMR spectra obtained with the hetero-dqf pulse sequence. In the solid state, these stereoelectronic effects were investigated by measurement of X-ray diffraction data, the molecular geometry (torsional bond angles and bond distances), and inter- and intramolecular interactions, and by natural bond orbital analysis, which was performed using density functional theory at the ωB97XD/6311++G(d,p) level. We found that one of the main factors influencing the conformational stability of 3-8 is the interaction between the lone-pair electrons of nitrogen and the antibonding sigma orbital of C(7)-Heq (nN→σ*C-H(7)eq), a type of hyperconjugative interaction. PMID:26664617

  2. Quality Improvement Practices in Academic Emergency Medicine: Perspectives from the Chairs

    PubMed Central

    DelliFraine, Jami; Langabeer, James; King, Brent

    2010-01-01

    Objective To assess academic emergency medicine (EM) chairs’ perceptions of quality improvement (QI) training programs. Methods A voluntary anonymous 20 item survey was distributed to a sample of academic chairs of EM through the Association of Academic Chairs of Emergency Medicine. Data was collected to assess the percentage of academic emergency physicians who had received QI training, the type of training they received, their perception of the impact of this training on behavior, practice and outcomes, and any perceived barriers to implementing QI programs in the emergency department. Results The response rate to the survey was 69% (N = 59). 59.3% of respondents report that their hospital has a formal QI program for physicians. Chairs received training in a variety of QI programs. The type of QI program used by respondents was perceived as having no impact on goals achieved by QI (χ2 = 12.382; p = 0.260), but there was a statistically significant (χ2 = 14.383; p = 0.006) relationship between whether or not goals were achieved and academic EM chairs’ perceptions about return on investment for QI training. Only 22% of chairs responded that they have already made changes as a result of the QI training. 78.8% of EM chairs responded that quality programs could have a significant positive impact on their practice and the healthcare industry. Chairs perceived that QI programs had the most potential value in the areas of understanding and reducing medical errors and improving patient flow and throughput. Other areas of potential value of QI include improving specific clinical indicators and standardizing physician care. Conclusion Academic EM chairs perceived that QI programs were an effective way to drive needed improvements. The results suggest that there is a high level of interest in QI but a low level of adoption of training and implementation. PMID:21293770

  3. Analysis of plethysmographic waveform changes induced by beach chair positioning under general anesthesia.

    PubMed

    Zhu, Richard; Atteya, Gourg; Shelley, Kirk H; Silverman, David G; Alian, Aymen A

    2014-12-01

    During shoulder surgery, patients typically are placed in the beach chair position. In rare cases, this positioning has resulted in devastating outcomes of postoperative cerebral ischemia (Cullen and Kirby in APSF Newsl 22(2):25-27, 2007; Munis in APSF Newsl 22(4):82-83, 2008). This study presents a method to noninvasively and continuously hemodynamically monitor patients during beach chair positioning by using the photoplethysmograph signal recorded from a commercial pulse oximeter. Twenty-nine adults undergoing shoulder surgery were monitored before and after beach chair positioning with electrocardiogram, intermittent blood pressure, end tidal carbon dioxide, and photoplethysmograph via Nellcor finger pulse oximeter. Fast Fourier transform (FFT) was used to perform frequency-domain analysis on the photoplethysmograph (PPG) signal for data segments taken 80-120 s before and after beach chair positioning. The amplitude density of respiration-associated PPG oscillations was quantified measuring the height of the FFT peak at respiratory frequency. Results were reported as (median, interquartile range) and statistical analysis was performed using Wilcoxon sign rank test. Data were also collected when vasoactive drugs phenylephrine and ephedrine were used to maintain acceptable mean arterial pressure during a case. With beach chair positioning, all subjects who did not receive vasoactive drugs showed an increase in the FFT amplitude density of respiration-associated PPG oscillations (p < 0.0001) without change in pulse-associated PPG oscillations. The PPG was more accurate at monitoring the change to beach chair position than blood pressure or heart rate. With vasoactive drugs, pulse-associated PPG oscillations decreased only with phenylephrine while respiration-associated oscillations did not change. Frequency domain analysis of the PPG signal may be a better tool than traditional noninvasive hemodynamic parameters at monitoring patients during beach chair

  4. [Conformers of carnosine].

    PubMed

    Kliuev, S A

    2006-01-01

    The geometric and energetic parameters of most stable conformations of carnosine were calculated by the semiempirical guantum-chemical method PM3. The carnosine-water-zinc (II) clusters were simulated. PMID:16909845

  5. Assemblies of Conformal Tanks

    NASA Technical Reports Server (NTRS)

    DeLay, Tom

    2009-01-01

    Assemblies of tanks having shapes that conform to each other and/or conform to other proximate objects have been investigated for use in storing fuels and oxidizers in small available spaces in upper stages of spacecraft. Such assemblies might also prove useful in aircraft, automobiles, boats, and other terrestrial vehicles in which space available for tanks is limited. The basic concept of using conformal tanks to maximize the utilization of limited space is not new in itself: for example, conformal tanks are used in some automobiles to store windshield -washer liquid and coolant that overflows from radiators. The novelty of the present development lies in the concept of an assembly of smaller conformal tanks, as distinguished from a single larger conformal tank. In an assembly of smaller tanks, it would be possible to store different liquids in different tanks. Even if the same liquid were stored in all the tanks, the assembly would offer an advantage by reducing the mechanical disturbance caused by sloshing of fuel in a single larger tank: indeed, the requirement to reduce sloshing is critical in some applications. The figure shows a prototype assembly of conformal tanks. Each tank was fabricated by (1) copper plating a wax tank mandrel to form a liner and (2) wrapping and curing layers of graphite/epoxy composite to form a shell supporting the liner. In this case, the conformal tank surfaces are flat ones where they come in contact with the adjacent tanks. A band of fibers around the outside binds the tanks together tightly in the assembly, which has a quasi-toroidal shape. For proper functioning, it would be necessary to maintain equal pressure in all the tanks.

  6. Quantum massive conformal gravity

    NASA Astrophysics Data System (ADS)

    Faria, F. F.

    2016-04-01

    We first find the linear approximation of the second plus fourth order derivative massive conformal gravity action. Then we reduce the linearized action to separated second order derivative terms, which allows us to quantize the theory by using the standard first order canonical quantization method. It is shown that quantum massive conformal gravity is renormalizable but has ghost states. A possible decoupling of these ghost states at high energies is discussed.

  7. ESA chairs the International Living With a Star programme

    NASA Astrophysics Data System (ADS)

    2003-02-01

    chairing the ILWS steering committee for the first two years. “There is a clear need to study the Sun and its interaction with the Earth” he says, “ and it is too big a job for a single space agency to cope with.” Notes to editors The new International Living With a Star (ILWS) programme builds upon a previous international framework between Europe, Japan, Russia (formerly the Soviet Union), and the United States to study the Sun and its effects on Earth. That framework was the International Solar Terrestrial Physics (ISTP) programme. The SOHO and Cluster missions were part of ESA’s contribution. For ILWS, the Canadian Space Agency has joined the collaboration. A ‘kick-off’ meeting between the space agencies involved in ILWS was held on 4-6 September 2002 in Washington DC, United States. An international steering committee of representatives from those agencies will now supervise the programme. The committee comprises five space agencies: the National Aeronautics and Space Administration (NASA), the European Space Agency (ESA), Japan's Institute for Space and Astronautical Science (ISAS), the Russian Aviation and Space Agency (Rosaviacosmos), and the Canadian Space Agency (CSA). There will be an ILWS Working Group to coordinate special projects. More than 20 space agencies have announced their participation in the first Working Group meeting, scheduled to take place in Nice, France, on 14 -15 April 2003. Contributions from the various space agencies include missions, payloads, subsystems, launch or tracking services, rockets, balloons, and open access to data sources.

  8. Conformational sampling techniques.

    PubMed

    Hatfield, Marcus P D; Lovas, Sándor

    2014-01-01

    The potential energy hyper-surface of a protein relates the potential energy of the protein to its conformational space. This surface is useful in determining the native conformation of a protein or in examining a statistical-mechanical ensemble of structures (canonical ensemble). In determining the potential energy hyper-surface of a protein three aspects must be considered; reducing the degrees of freedom, a method to determine the energy of each conformation and a method to sample the conformational space. For reducing the degrees of freedom the choice of solvent, coarse graining, constraining degrees of freedom and periodic boundary conditions are discussed. The use of quantum mechanics versus molecular mechanics and the choice of force fields are also discussed, as well as the sampling of the conformational space through deterministic and heuristic approaches. Deterministic methods include knowledge-based statistical methods, rotamer libraries, homology modeling, the build-up method, self-consistent electrostatic field, deformation methods, tree-based elimination and eigenvector following routines. The heuristic methods include Monte Carlo chain growing, energy minimizations, metropolis monte carlo and molecular dynamics. In addition, various methods to enhance the conformational search including the deformation or smoothing of the surface, scaling of system parameters, and multi copy searching are also discussed. PMID:23947647

  9. Two-dimensionally stacked heterometallic layers hosting a discrete chair dodecameric ring of water clusters: synthesis and structural study.

    PubMed

    Kenfack Tsobnang, Patrice; Wenger, Emmanuel; Biache, Coralie; Lambi Ngolui, John; Ponou, Siméon; Dahaoui, Slimane; Lecomte, Claude

    2014-10-01

    The stacked two-dimensional supramolecular compound catena-{Co(amp)3Cr(ox)3·6H2O} (amp = 2-picolylamine, ox = oxalate) has been synthesized from the bimolecular approach using hydrogen bonds. It is built from layers in which both Co(amp)(3+) (D) and Cr(ox)(3-) (A) ions are bonded in a repeating DADADA… pattern along the a and c axes by multiple hydrogen bonds. These layers host a well resolved R12 dodecameric discrete ring of water clusters built by six independent molecules located around the 2c centrosymmetric Wyckoff positions of the P21/n space group in which the compound crystallizes. These clusters are ranged along the [001] direction, occupy 733.5 Å(3) (22.0%) of the unit cell and have a chair conformation via 12 hydrogen bonds. The water molecules of the cluster are linked with stronger hydrogen bonds than those between the cluster and its host, which explains the single continuous step of the dehydration process of the compound. PMID:25274525

  10. [Self-made "electric chair" for sexually motivated child abuse of children].

    PubMed

    Rothschild, Markus A; Vendura, Klaus; Kell, Gerald

    2007-01-01

    A 52-year-old man had altered a wooden folding chair by placing two electrodes and a circuit underneath the seat. Using a remote control, he was able to give electric shocks to a person sitting on the chair. He used this device on more than 50 children, video-taping their reactions for his own pleasure. There are no reports that any of the children suffered a lasting damage to their health. The construction as well as the function and the electrical parameters of the chair were examined by forensic specialists. According to their expertise, the construction was not able to cause a potentially life-threatening condition when used with healthy children. The perpetrator was convicted for bodily harm etc. PMID:18020140

  11. Effects of differences in office chair controls, seat and backrest angle design in relation to tasks.

    PubMed

    Groenesteijn, Liesbeth; Vink, Peter; de Looze, Michiel; Krause, Frank

    2009-05-01

    In this study the influence of chair characteristics on comfort, discomfort, adjustment time and seat interface pressure is investigated during VDU and non-VDU tasks: The two investigated office chairs, both designed according to European and Dutch standards are different regarding: 1) seat cushioning and shape, 2) backrest angle and 3) controls. Thirty subjects in total, both male and female, participated in two experiments: twenty in the first and ten in the second. Significant differences are found for ease of adjustment and adjustment time of controls, independent of the tasks. Related to tasks, a significant difference was found for the backrest range of motion. For non-VDU tasks a larger range of backrest motion was preferred by 70% of the subjects. The chair design differences were most clear for comfort and adjustment time of controls, followed by comfort of backrest angle. No differences are found between seat pan comfort and discomfort, first impressions and peak interface pressure. PMID:19135185

  12. The "Chair Campaign" in Korea: an alternative approach in occupational health and safety for service workers.

    PubMed

    Lee, Yun-Keun; Kim, Shin-Bum; Chung, Jinjoo; Jung, Min-Jung; Kim, Myoung-Hee

    2011-01-01

    In spite of the increasing number of service workers in Korea, their occupational health and safety concerns have largely been neglected. It is in this context that the Chair Campaign, which lasted four months, was launched as an alternative occupational health approach for service workers. The campaign succeeded in getting wide public support, bringing about a special inspection by the Ministry of Labor. Finally, chairs were provided for workers at checkout counters in 71 department stores and 449 large discount stores. However, there are still many workplaces where workers cannot sit, whether chairs are provided or not. Although there is still much to be done, this campaign raised social awareness that service workers, mainly women, have the right to work in healthy and safe conditions. This paper will review the campaign and evaluate its achievements and limitations. PMID:21733805

  13. The founder and head of the Chair of Theoretical Physics of the Yerevan State University

    NASA Astrophysics Data System (ADS)

    Grigoryan, L. Sh

    2014-03-01

    The paper is dedicated to the Centenary of an Academician of NAS RA, Professor G S Sahakyan's birth, the Man that founded and headed the Chair of Theoretical Physics (CTP) of the Yerevan State University for almost half a century. The reference to school days of G S Sahakyan is made, information about his 7 years long service in the forces in the fields, about the establishment and administration by him of the Chair of Theoretical Physics in the Yerevan State University, about his collaboration with academician V A Ambartsumian, about the research associates of the G S Sahakyan's Chair, the students of CTP and the advancement of theoretical physics in Armenia is given. The personality characteristics of G S Sahakyan as a principal investigator and leader of CTP are analyzed.

  14. Conformal Collineations in String Cosmology

    NASA Astrophysics Data System (ADS)

    Baysal, Hüsnü; Camci, U.ğur; Tarhan, İsmail; Yilmaz, İhsan; Yavuz, İlhami; Dolgov, A.

    In this paper, we study the consequences of the existence of conformal collineations (CC) for string cloud in the context of general relativity. Especially, we interest in special conformal collineation (SCC), generated by a special affine conformal collineation (SACC) in the string cloud. Some results on the restrictions imposed by a conformal collineation symmetry in the string cloud are obtained.

  15. Conformational kinetics reveals affinities of protein conformational states

    PubMed Central

    Daniels, Kyle G.; Suo, Yang; Oas, Terrence G.

    2015-01-01

    Most biological reactions rely on interplay between binding and changes in both macromolecular structure and dynamics. Practical understanding of this interplay requires detection of critical intermediates and determination of their binding and conformational characteristics. However, many of these species are only transiently present and they have often been overlooked in mechanistic studies of reactions that couple binding to conformational change. We monitored the kinetics of ligand-induced conformational changes in a small protein using six different ligands. We analyzed the kinetic data to simultaneously determine both binding affinities for the conformational states and the rate constants of conformational change. The approach we used is sufficiently robust to determine the affinities of three conformational states and detect even modest differences in the protein’s affinities for relatively similar ligands. Ligand binding favors higher-affinity conformational states by increasing forward conformational rate constants and/or decreasing reverse conformational rate constants. The amounts by which forward rate constants increase and reverse rate constants decrease are proportional to the ratio of affinities of the conformational states. We also show that both the affinity ratio and another parameter, which quantifies the changes in conformational rate constants upon ligand binding, are strong determinants of the mechanism (conformational selection and/or induced fit) of molecular recognition. Our results highlight the utility of analyzing the kinetics of conformational changes to determine affinities that cannot be determined from equilibrium experiments. Most importantly, they demonstrate an inextricable link between conformational dynamics and the binding affinities of conformational states. PMID:26162682

  16. Sedative music reduces anxiety and pain during chair rest after open-heart surgery.

    PubMed

    Voss, Jo A; Good, Marion; Yates, Bernice; Baun, Mara M; Thompson, Austin; Hertzog, Melody

    2004-11-01

    Open-heart surgery patients report anxiety and pain with chair rest despite opioid analgesic use. The effectiveness of non-pharmacological complementary methods (sedative music and scheduled rest) in reducing anxiety and pain during chair rest was tested using a three-group pretest-posttest experimental design with 61 adult postoperative open-heart surgery patients. Patients were randomly assigned to receive 30 min of sedative music (N=19), scheduled rest (N=21), or treatment as usual (N=21) during chair rest. Anxiety, pain sensation, and pain distress were measured with visual analogue scales at chair rest initiation and 30 min later. Repeated measures MANOVA indicated significant group differences in anxiety, pain sensation, and pain distress from pretest to posttest, P<0.001. Univariate repeated measures ANOVA (P< or =0.001) and post hoc dependent t-tests indicated that in the sedative music and scheduled rest groups, anxiety, pain sensation, and pain distress all decreased significantly, P<0.001-0.015; while in the treatment as usual group, no significant differences occurred. Further, independent t-tests indicated significantly less posttest anxiety, pain sensation, and pain distress in the sedative music group than in the scheduled rest or treatment as usual groups (P<0.001-0.006). Thus, in this randomized control trial, sedative music was more effective than scheduled rest and treatment as usual in decreasing anxiety and pain in open-heart surgery patients during first time chair rest. Patients should be encouraged to use sedative music as an adjuvant to medication during chair rest. PMID:15494201

  17. Conformational flexibility of mephenesin.

    PubMed

    Écija, Patricia; Evangelisti, Luca; Vallejo, Montserrat; Basterretxea, Francisco J; Lesarri, Alberto; Castaño, Fernando; Caminati, Walther; Cocinero, Emilio J

    2014-05-22

    The mephenesin molecule (3-(2-methylphenoxy)propane-1,2-diol) serves as a test bank to explore several structural and dynamical issues, such as conformational flexibility, the orientation of the carbon linear chain relative to the benzene plane, or the effect of substituent position on the rotational barrier of a methyl group. The molecule has been studied by rotational spectroscopy in the 4-18 GHz frequency range by Fourier-transform methods in a supersonic expansion. The experiment has been backed by a previous conformational search plus optimization of the lowest energy structures by ab initio and density functional quantum calculations. The three lowest-lying conformers that can interconvert to each other by simple bond rotations have been detected in the jet. Rotational parameters for all structures have been obtained, and methyl torsional barriers have been determined for the two lowest-lying rotamers. The lowest-lying structure of mephenesin is highly planar, with all carbon atoms lying nearly in the benzene ring plane, and is stabilized by the formation of cooperative intramolecular hydrogen bonding. An estimation of the relative abundance of the detected conformers indicates that the energetically most stable conformer will have an abundance near 80% at temperatures relevant for biological activity. PMID:24754523

  18. Conformers of Gaseous Serine.

    PubMed

    He, Kedan; Allen, Wesley D

    2016-08-01

    The myriad conformers of the neutral form of natural amino acid serine (Ser) have been investigated by systematic computations with reliable electronic wave function methods. A total of 85 unique conformers were located using the MP2/cc-pVTZ level of theory. The 12 lowest-energy conformers of serine fall within a 8 kJ mol(-1) window, and for these species, geometric structures, precise relative energies, equilibrium and vibrationally averaged rotational constants, anharmonic vibrational frequencies, infrared intensities, quartic and sextic centrifugal distortion constants, dipole moments, and (14)N nuclear quadrupole coupling constants were computed. The relative energies were refined through composite focal-point analyses employing basis sets as large as aug-cc-pV5Z and correlation treatments through CCSD(T). The rotational constants for seven conformers measured by Fourier-transform microwave spectroscopy are in good agreement with the vibrationally averaged rotational constants computed in this study. Our anharmonic vibrational frequencies are compared to the large number of experimental vibrational absorptions attributable to at least six conformers. PMID:27294314

  19. A Profile of Academic Training Program Directors and Chairs in Radiation Oncology

    SciTech Connect

    Wilson, Lynn D.; Haffty, Bruce G.; Smith, Benjamin D.

    2013-04-01

    Purpose: To identify objective characteristics and benchmarks for program leadership in academic radiation oncology. Methods and Materials: A study of the 87 Accreditation Council for Graduate Medical Education radiation oncology training program directors (PD) and their chairs was performed. Variables included age, gender, original training department, highest degree, rank, endowed chair assignment, National Institutes of Health (NIH) funding, and Hirsch index (H-index). Data were gathered from online sources such as departmental websites, NIH RePORTER, and Scopus. Results: There were a total of 87 PD. The median age was 48, and 14 (16%) were MD/PhD. A total of 21 (24%) were female, and rank was relatively equally distributed above instructor. Of the 26 professors, at least 7 (27%) were female. At least 24 (28%) were working at the institution from which they had received their training. A total of 6 individuals held endowed chairs. Only 2 PD had active NIH funding in 2012. The median H-index was 12 (range, 0-51) but the index dropped to 9 (range, 0-38) when those who served as both PD and chair were removed from the group. A total of 76 chairs were identified at the time of the study. The median age was 55, and 9 (12%) were MD/PhD. A total of 7 (9%) of the chairs were female, and rank was professor for all with the exception of 1 who was listed as “Head” and was an associate professor. Of the 76 chairs, at least 10 (13%) were working at the institution from which they received their training. There were a total of 21 individuals with endowed chairs. A total of 13 (17%) had NIH funding in 2012. The median H-index was 29 (range, 3-60). Conclusions: These data provide benchmarks for individuals and departments evaluating leadership positions in the field of academic radiation oncology. Such data are useful for evaluating leadership trends over time and comparing academic radiation oncology with other specialties.

  20. Reflections from a chair: Leadership of a clinical department at an academic medical center.

    PubMed

    Willett, Christopher G

    2015-11-01

    The leadership position of an academic departmental chair can be a positive and rewarding opportunity. These rewards principally stem from the success of the faculty, residents, other trainees, nurses, and everyone supporting the department. With health care reform and the constraints of the federal budget, increasing attention and time has become directed toward administrative management. There are multiple and often competing constituencies and agendas requiring thoughtful strategies to achieve departmental goals. The objectives of a chair are advancing patient care, education, and research. True excellence of a department is achieved by the innovation of its faculty. PMID:26218104

  1. Abnormal sitting pressures of hemiplegic cerebral palsy children on a school chair

    PubMed Central

    Lee, In-Hee; Park, Sang-young

    2015-01-01

    [Purpose] The purpose of this study was to investigate the differences in symmetry of sitting posture between typical developmental (TD) children and hemi-cerebral palsy (CP) children. [Subjects and Methods] A school chair mounted on a force platform was used to assess the quiet-sitting pressure distribution of 10 TD and 10 CP children. [Results] The symmetry index of the TD children was significantly closer to zero than that of the CP children irrespective of the latter group’s hemiparetic side. [Conclusions] Sitting posture on school chairs of CP children was more asymmetrical than that of TD children. PMID:25729201

  2. Synthesis, structural, conformational and pharmacological study of some carbamates derived from 3-methyl-2,4-diphenyl-3- azabicyclo[3.3.1]nonan-9α-ol

    NASA Astrophysics Data System (ADS)

    Iriepa, I.; Gil-Alberdi, B.; Gálvez, E.; Bellanato, J.; Carmona, P.

    1997-04-01

    A series of benzimidazole and benzothiazole carbamates derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-ol has been synthesized and studied by IR, Raman, 1H and 13C NMR spectroscopy. The compounds studied display in CDCl 3 a preferred flattened chair-chair conformation. IR (at room and variable temperature) and 1H and 13C NMR data show the presence of an intramolecular NH…OC hydrogen bond in the benzimidazole carbamates. Pharmacological assays on mice were performed to evaluate analgesic activity as well as drug-induced behavioral alterations.

  3. Synthesis, structural, conformational and pharmacological study of some carbamates derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9 β-ol

    NASA Astrophysics Data System (ADS)

    Iriepa, I.; Gil-Alberdi, B.; Gálvez, E.; Villasante, F. J.; Bellanato, J.; Carmona, P.

    1999-05-01

    A series of benzimidazole and benzothiazole carbamates derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9 β-ol were synthesized and studied by IR, Raman, 1H and 13C NMR spectroscopy. The compounds studied displayed in CDCl 3 solution a preferred flattened chair-chair conformation. IR and 1H and 13C NMR data showed the presence of an intramolecular hydrogen bond in the benzimidazole carbamates. Pharmacological assays on mice were drawn to evaluate analgesic activity as well as drug-induced behavioral alterations.

  4. Extended conformal algebras

    NASA Astrophysics Data System (ADS)

    Bouwknegt, Peter

    1988-06-01

    We investigate extensions of the Virasoro algebra by a single primary field of integer or halfinteger conformal dimension Δ. We argue that for vanishing structure constant CΔΔΔ, the extended conformal algebra can only be associative for a generic c-value if Δ=1/2, 1, 3/2, 2 or 3. For the other Δ<=5 we compute the finite set of allowed c-values and identify the rational solutions. The case CΔΔΔ≠0 is also briefly discussed. I would like to thank Kareljan Schoutens for discussions and Sander Bais for a careful reading of the manuscript.

  5. Charged conformal Killing spinors

    SciTech Connect

    Lischewski, Andree

    2015-01-15

    We study the twistor equation on pseudo-Riemannian Spin{sup c}-manifolds whose solutions we call charged conformal Killing spinors (CCKSs). We derive several integrability conditions for the existence of CCKS and study their relations to spinor bilinears. A construction principle for Lorentzian manifolds admitting CCKS with nontrivial charge starting from CR-geometry is presented. We obtain a partial classification result in the Lorentzian case under the additional assumption that the associated Dirac current is normal conformal and complete the classification of manifolds admitting CCKS in all dimensions and signatures ≤5 which has recently been initiated in the study of supersymmetric field theories on curved space.

  6. Gas-Phase Infrared and NMR Investigation of the Conformers of Diacetone Diperoxide (DADP).

    PubMed

    Guo, Chunlei; Persons, John; Woodford, Jeffrey N; Harbison, Gerard S

    2015-10-01

    Gas-phase infrared measurements of diacetone diperoxide (DADP) indicate a chair conformation with less than 5% of the predicted twist conformer. Vibrational frequencies are very similar to those previously measured in the solid state. Solution NMR measurements using 2D exchange spectroscopy (EXSY) also set a very low maximum limit on the equilibrium population of the twist conformer, with a room-temperature free-energy difference in excess of 14.5 kJ/mol. These experimental results are in accord with high-level quantum calculations incorporating full thermochemistry and solvation effects, which indicate a free-energy difference in the range of 14.7-17.5 kJ/mol in polar solvents. PMID:26387762

  7. Conformal cloak for waves

    SciTech Connect

    Chen Huanyang; Leonhardt, Ulf; Tyc, Tomas

    2011-05-15

    Conformal invisibility devices are only supposed to work within the valid range of geometrical optics. Here, we show by numerical simulations and analytical arguments that for certain quantized frequencies, they are nearly perfect even in a regime that clearly violates geometrical optics. The quantization condition follows from the analogy between the Helmholtz equation and the stationary Schroedinger equation.

  8. Extended conformal field theories

    NASA Astrophysics Data System (ADS)

    Taormina, Anne

    1990-08-01

    Some extended conformal field theories are briefly reviewed. They illustrate how non minimal models of the Virasoro algebra (c≥1) can become minimal with respect to a larger algebra. The accent is put on N-extended superconformal algebras, which are relevant in superstring compactification.

  9. PERSONALITY AND CONFORMITY.

    ERIC Educational Resources Information Center

    BAROCAS, RALPH; GORLOW, LEON

    AN INVESTIGATION WAS MADE OF THE RELATIONSHIP BETWEEN PERSONALITY FACTORS AND CONFORMITY. THE SUBJECTS WERE 243 RANDOMLY SELECTED STUDENTS ENROLLED IN COLLEGE PSYCHOLOGY COURSES WHO WERE DIVIDED INTO GROUPS OF 97, 96, AND 50 SUBJECTS. A PERSONALITY FACTOR INVENTORY WAS OBTAINED FROM RESPONSES TO A LARGE LIST OF TRUE-FALSE PERSONALITY ITEM…

  10. Animal culture: chimpanzee conformity?

    PubMed

    van Schaik, Carel P

    2012-05-22

    Culture-like phenomena in wild animals have received much attention, but how good is the evidence and how similar are they to human culture? New data on chimpanzees suggest their culture may even have an element of conformity. PMID:22625856

  11. 75 FR 11120 - Folding Metal Tables and Chairs from the People's Republic of China: Notice of Extension of Time...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... metal tables and chairs from the People's Republic of China (``PRC''). See Initiation of Antidumping and Countervailing Duty Administrative Reviews and Deferral of Administrative Review, 74 FR 37690 (July 29, 2009... International Trade Administration Folding Metal Tables and Chairs from the People's Republic of China:...

  12. 77 FR 59975 - Certain Folding Metal Tables and Chairs From China; Institution of a Five-Year Review Concerning...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... an antidumping duty order on imports of certain folding metal tables and chairs from China (67 FR... part 201), and part 207, subparts A, D, E, and F (19 CFR part 207), as most recently amended at 74 FR... chairs from China (72 FR 62626). The Commission is now conducting a second review to determine...

  13. An Investigation of the National School Board Association Key Work Standards for Public Policy Leadership and School Board Chair Performance

    ERIC Educational Resources Information Center

    Quarles, Roger C.

    2011-01-01

    This multiple case qualitative study addressed the National School Board Association's (NSBA) Key Work standards for public policy leadership by local school boards, and how three elite school board chairs understood and implemented those standards. Elite board chair status was defined by experience, training, and peer recognition. The study…

  14. Conformational changes in biopolymers

    NASA Astrophysics Data System (ADS)

    Ivanov, Vassili

    2005-12-01

    Biopolymer conformational changes are involved in many biological processes. This thesis summarizes some theoretical and experimental approaches which I have taken at UCLA to explore conformational changes in biopolymers. The reversible thermal denaturation of the DNA double helix is, perhaps, the simplest example of biopolymer conformational change. I have developed a statistical mechanics model of DNA melting with reduced degrees of freedom, which allows base stacking interaction to be taken into account and treat base pairing and stacking separately. Unlike previous models, this model describes both the unpairing and unstacking parts of the experimental melting curves and explains the observed temperature dependence of the effective thermodynamic parameters used in models of the nearest neighbor type. I developed a basic kinetic model for irreversible thermal denaturation of F-actin, which incorporates depolymerization of F-actin from the ends and breaking of F-actin fiber in the middle. The model explains the cooperativity of F-actin thermal denaturation observed by D. Pavlov et al. in differential calorimetry measurements. CG-rich DNA sequences form left-handed Z-DNA at high ionic strength or upon binding of polyvalent ions and some proteins. I studied experimentally the B-to-Z transition of the (CG)6 dodecamer. Improvement of the locally linearized model used to interpret the data gives evidence for an intermediate state in the B-to-Z transition of DNA, contrary to previous research on this subject. In the past 15 years it has become possible to study the conformational changes of biomolecules using single-molecule techniques. In collaboration with other lab members I performed a single-molecule experiment, where we monitored the displacement of a micrometer-size bead tethered to a surface by a DNA probe undergoing the conformational change. This technique allows probing of conformational changes with subnanometer accuracy. We applied the method to detect

  15. The effect of Sit 'n' Fit Chair Yoga among community-dwelling older adults with osteoarthritis.

    PubMed

    Park, Juyoung; McCaffrey, Ruth; Newman, David; Cheung, Corjena; Hagen, Dyana

    2014-01-01

    The study measured effects of Sit 'N' Fit Chair Yoga on pain and physical and psychological functioning. A quasi-experimental research design included a yoga intervention group and an attention control group. There was greater improvement in depression and life satisfaction in the yoga group than in the control group. PMID:24919095

  16. Principals Fostering the Instructional Leadership Capacities of Department Chairs: A Strategy for Urban High School Reform

    ERIC Educational Resources Information Center

    Klar, Hans W.

    2013-01-01

    A growing body of literature has highlighted the affordances of distributive forms of instructional leadership as a means to broaden and deepen instructional leadership capacity within schools. Yet, specifically how the capabilities of such key leaders as high school department chairs can be fostered to realize enhanced instructional capacity…

  17. Defining and Activating the Role of Department Chair as Instructional Leader

    ERIC Educational Resources Information Center

    Kelley, Carolyn; Salisbury, Jason

    2013-01-01

    With strong connection to schoolwide policy and vision and to the realities of the daily life of teachers and students, the department chair is uniquely positioned to play an important role in advancing instructional effectiveness (Printy, 2008; Weller, 2001). This article provides an in-depth look at the efforts of three urban comprehensive high…

  18. Cultivating Sacramentality through Administrative Work: Guidance from St. Benedict on Being a Catholic Department Chair

    ERIC Educational Resources Information Center

    Narloch, Rodger

    2014-01-01

    One dilemma encountered by department chairs and administrators at Catholic colleges and universities is how to respect the pluralistic religious views of the faculty while being faithful to one's own and the institution's Catholic tradition. The Rule of St. Benedict offers guidance that can result in deepening the respect for all…

  19. The Department Chair's Role in Developing New Faculty into Teachers and Scholars.

    ERIC Educational Resources Information Center

    Bensimon, Estela Mara; Ward, Kelly; Sanders, Karla

    This book is designed to help department chairs with three stages of junior faculty socialization: recruitment and hiring; the critical first year; and evaluating the performance of new faculty. The book is organized in three parts with 15 chapters. Chapters in Part 1, "Managing the Recruitment and Selection of New Faculty," include: (1)…

  20. Resolving Decisional Conflict by Gestalt Two-Chair Dialogue: Relating Process to Outcome.

    ERIC Educational Resources Information Center

    Greenberg, Leslie S.; Webster, Michael C.

    1982-01-01

    Clients (N=31) completed a six-week program using Gestalt two-chair dialog to work on intrapsychic conflict related to the making of a decision. Clients were classified as resolvers or nonresolvers. Resolvers were found to be significantly less undecided and less anxious after treatment. (Author)

  1. Views from a Distance: A Nephological Model of the CCCC Chairs' Addresses, 1977-2011

    ERIC Educational Resources Information Center

    Mueller, Derek N.

    2012-01-01

    Views from a Distance is a series of word clouds rendered from 35 chairs' addresses delivered at CCCC conventions from 1977 to 2011. The digital installation invites explorations of word-level patterns and anomalies within this widely recognized collection of speeches. The installation itself is underpinned with the assumption that distinctive…

  2. Designing and Building a Cardboard Chair: Children's Engineering at the TECA Eastern Regional Conference

    ERIC Educational Resources Information Center

    Linnell, Charles C.

    2007-01-01

    This article describes the 2006 Technology Education Collegiate Association (TECA) Eastern Regional elementary competition, wherein teams of technology education students from nine different universities designed and built cardboard chairs. The competition required the teams (four or five to a team) from universities up and down the East Coast to…

  3. Governance under Siege: An Interview with the Chair of the Northern Illinois University Board of Trustees

    ERIC Educational Resources Information Center

    Trusteeship, 2008

    2008-01-01

    On February 14, a former graduate student at Northern Illinois University (NIU) entered a campus building and shot 21 people, wounding five fatally, before he shot and killed himself. This article presents an interview with Cherilyn G. Murer, the Chair of the Northern Illinois University Board of Trustees, on the actions taken by the board and the…

  4. Leadership Strategies of Exemplary High School Department Chairs: Four Case Studies of Successful "Middle Managers."

    ERIC Educational Resources Information Center

    Wettersten, Jill A.

    This paper presents findings of case studies that applied social exchange theory to examine the instructional leadership roles of four exemplary high school department chairs. Data were gathered at four suburban high schools in a large metropolitan area of the midwestern United States using the methods of observation and interviews with the…

  5. 20 CFR 661.320 - Who must chair a Local Board?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Who must chair a Local Board? 661.320 Section 661.320 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) STATEWIDE AND LOCAL GOVERNANCE OF THE WORKFORCE INVESTMENT SYSTEM UNDER TITLE I OF THE WORKFORCE...

  6. The Cockpit's Empty Chair: Education through Appropriating Alienation at a Chicago Technology Museum

    ERIC Educational Resources Information Center

    Lormier, Anne

    2007-01-01

    Background/Context: In the United States, the percentage of schoolchildren planning to become high-status professionals is grossly disproportionate to the percentage of such jobs comprising our division of labor. As in a game of musical chairs, it is not structurally possible for everyone to remain a contender. Focus of Study: Various adults who…

  7. Tenure Standards in Political Science Departments: Results from a Survey of Department Chairs

    ERIC Educational Resources Information Center

    Rothgeb, John M., Jr.; Burger, Betsy

    2009-01-01

    This article presents the results from a survey of political science department chairs regarding the tenure procedures and standards at their colleges or universities. The findings reveal that only a small fraction of the colleges and universities in the United States refuse to offer tenure or are attempting to limit tenure. We also find general…

  8. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Posture chair for cardiac or pulmonary treatment. 868.5365 Section 868.5365 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture...

  9. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Posture chair for cardiac or pulmonary treatment. 868.5365 Section 868.5365 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture...

  10. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Posture chair for cardiac or pulmonary treatment. 868.5365 Section 868.5365 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture...

  11. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Posture chair for cardiac or pulmonary treatment. 868.5365 Section 868.5365 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture...

  12. 21 CFR 868.5365 - Posture chair for cardiac or pulmonary treatment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Posture chair for cardiac or pulmonary treatment. 868.5365 Section 868.5365 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5365 Posture...

  13. Evaluation of Chair-Side Assays in High Microbiological Caries-Risk Subjects.

    PubMed

    Saravia, Marta Estela; Silva, Lea Assed Bezerra; Silva, Raquel Assed Bezerra; Lucisano, Marília Pacífico; Echevarría, Andrea Uribe; Echevarría, Jorge Uribe; Nelson-Filho, Paulo

    2015-01-01

    The aim of this study was to evaluate the commercial chair-side assays Saliva-Check Mutans and ClinproTM Cario L-PopTM in high microbiological caries-risk dental students compared with conventional semi-quantitative colony counting culture-based technique as the reference method. Saliva samples from 93 subjects of both sexes aged 18-26 years were seeded (Köhler and Bratthall method) on plates containing SB-20M culture medium method and 12 subjects with high caries risk were selected. These 12 individuals were subjected to determination of caries risk using two commercial rapid detection chair-side assays (Saliva-Check Mutans and ClinproTM Cario L-PopTM) according to the manufacturers' instructions. The results were analyzed by the Kappa correlation test using SAS statistical software. There was a perfect agreement (Kappa=1) among the three caries risk evaluation methods - chair-side assays and semi-quantitative CFU count (control) - in all subjects. The results suggest that the commercial chair-side assays evaluated in this study may be practical and useful to identify high microbiological caries-risk subjects. PMID:26963201

  14. Observation of Classroom Performance Using Therapy Balls as a Substitute for Chairs in Elementary School Children

    ERIC Educational Resources Information Center

    Burgoyne, Molly E.; Ketcham, Caroline J.

    2015-01-01

    Many classrooms are beginning to substitute standard chairs with therapy balls, which help to improve students' focus and classroom performance, according to teacher and student reports. Researchers conducted an observational study in a classroom at a local elementary school that implemented therapy balls. For each hour-long observation, three…

  15. What Every Department Chair Should Know about the Dean: Findings from Four National Surveys.

    ERIC Educational Resources Information Center

    Bowker, Lee H.; Lynch, David M.

    Information about deans that may be helpful to department chairs is presented, based on the findings of four national surveys of deans. The surveys of social science, graduate, continuing education, and arts and sciences deans covered the deans' role in resource allocation to departments, teaching and research support for faculty, tenure and…

  16. Design of Lesehan Chair by Using Kansei Engineering Method And Anthropometry Approach

    NASA Astrophysics Data System (ADS)

    Pambudi, A. T.; Suryoputro, M. R.; Sari, A. D.; Kurnia, R. D.

    2016-01-01

    Special Region of Yogyakarta (DIY) is known as city for academic. Many people come to get some education in college. They live in boarding house with some supporting facilities. The most common facilities is low table which lead students have to sit on the floor while studying on table which could cause higher risk of back pain and musculoskeletal disorder. To identify the solution to reduce back pain and musculoskeletal risk, it is needed to design a lesehan chair which also appropriate to customer needs. Kansei engineering method was used with a total of 30 respondents participated, 15 kansei words collected, and 12 kansei words selected by doing validation and reliability test. The result of this study showed that quality, aesthetics, and comfort level influence the design of lesehan chair. A design of lesehan chair was created by considering the suitable concept and merging it with the physical design and its anthropometry measurement. In this case, marginal homogeneity test is needed to identify the differences between each kansei words attribute and the design or product recommendation. The marginal homogeneity test results show that the design and product recommendation has fulfilled customer's desires and needs. For further research, it is needed to analyse and evaluate the posture of lesehan chair users in order to develop and improve its performance.

  17. CCSF Survey on Using Technology: Administrators, Department Chairs, Classified Staff, and Student Services.

    ERIC Educational Resources Information Center

    City Coll. of San Francisco, CA. Office of Institutional Research, Planning and Grants.

    This document discusses the findings of a survey completed by all employees of City College of San Francisco in 2003. The employees surveyed include administrators, department chairs, classified staff, and student service faculty. The survey discovered that these employees differ from instructional faculty in the following ways: (1) they do their…

  18. 21 CFR 878.4950 - Manual operating table and accessories and manual operating chair and accessories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Manual operating table and accessories and manual operating chair and accessories. 878.4950 Section 878.4950 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY...

  19. 21 CFR 878.4950 - Manual operating table and accessories and manual operating chair and accessories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Manual operating table and accessories and manual operating chair and accessories. 878.4950 Section 878.4950 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY...

  20. 21 CFR 878.4960 - Operating tables and accessories and operating chairs and accessories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Operating tables and accessories and operating chairs and accessories. 878.4960 Section 878.4960 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES...

  1. 21 CFR 878.4960 - Operating tables and accessories and operating chairs and accessories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Operating tables and accessories and operating chairs and accessories. 878.4960 Section 878.4960 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES...

  2. 21 CFR 878.4960 - Operating tables and accessories and operating chairs and accessories.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Operating tables and accessories and operating chairs and accessories. 878.4960 Section 878.4960 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES...

  3. 21 CFR 878.4960 - Operating tables and accessories and operating chairs and accessories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Operating tables and accessories and operating chairs and accessories. 878.4960 Section 878.4960 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES...

  4. 21 CFR 878.4950 - Manual operating table and accessories and manual operating chair and accessories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Manual operating table and accessories and manual operating chair and accessories. 878.4950 Section 878.4950 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY...

  5. 21 CFR 878.4960 - Operating tables and accessories and operating chairs and accessories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Operating tables and accessories and operating chairs and accessories. 878.4960 Section 878.4960 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES...

  6. 21 CFR 878.4950 - Manual operating table and accessories and manual operating chair and accessories.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Manual operating table and accessories and manual operating chair and accessories. 878.4950 Section 878.4950 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY...

  7. K-theory of the chair tiling via AF-algebras

    NASA Astrophysics Data System (ADS)

    Julien, Antoine; Savinien, Jean

    2016-08-01

    We compute the K-theory groups of the groupoid C∗-algebra of the chair tiling, using a new method. We use exact sequences of Putnam to compute these groups from the K-theory groups of the AF-algebras of the substitution and the induced lower dimensional substitutions on edges and vertices.

  8. Differential Effects of the Gestalt Two-Chair Intervention and Problem Solving in Resolving Decisional Conflict.

    ERIC Educational Resources Information Center

    Clarke, Katherine M.; Greenberg, Leslie S.

    1986-01-01

    Compared an affective (Gestalt two-chair intervention) and a cognitive-behavioral (problem-solving) counseling intervention used to help clients resolve intrapersonal conflicts related to a decision. A one-way analysis of variance revealed that affective intervention was more effective than cognitive behavioral intervention or no treatment for…

  9. Pity the Program Chair: A Brief Guide to Preparing Academic Proposals.

    ERIC Educational Resources Information Center

    Bowman, Joel P.

    1994-01-01

    Discusses conference program proposals from the perspective of a former cochair of several international and regional scholarly conference committees. Describes the duties of program chairs. Outlines the way conference program decisions are meted out. Provides suggestions for perfect conference proposals. (HB)

  10. 76 FR 17118 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... Board is to make recommendations to DOE-EM and site management in the areas of environmental...

  11. 75 FR 17701 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... environmental restoration, waste management, and related activities. Tentative Agenda Topics: Wednesday,...

  12. 78 FR 20311 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of Open Webinar. SUMMARY: This notice announces a webinar of the Environmental Management Site-Specific... recommendations to DOE-EM and site management in the areas of environmental restoration, waste management,...

  13. 76 FR 62054 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open teleconference. SUMMARY: This notice announces a teleconference of the Environmental Management... make recommendations to DOE-EM and site management in the areas of environmental restoration,...

  14. 77 FR 55813 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... Board is to make recommendations to DOE-EM and site management in the areas of environmental...

  15. 78 FR 59012 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-25

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... environmental restoration, waste management, and related activities. Tentative Agenda Topics: Wednesday,...

  16. 75 FR 51450 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... the Board is to make recommendations ] to DOE-EM and site management in the areas of...

  17. 78 FR 64208 - Environmental Management Site-Specific Advisory Board Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... Environmental Management Site-Specific Advisory Board Chairs AGENCY: Department of Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces a meeting of the Environmental Management Site-Specific... environmental restoration, waste management, and related activities. Tentative Agenda Topics: Tuesday,...

  18. The Role of the Chair of the School Governing Body in England

    ERIC Educational Resources Information Center

    James, Chris; Jones, Jeff; Connolly, Michael; Brammer, Steve; Fertig, Mike; James, Jane

    2012-01-01

    The research reported here analysed the role of the chair of the school governing body in England, drawing on a national survey of governors and the study of governing in 30 schools. The role encompassed: being a governor; appointing and working with the head teacher; acting as a change agent; active participation in the school; organising the…

  19. 76 FR 45845 - Notice of Issuance of Final Determination Concerning a Certain Patient Transport Chair

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... Border Protection (``CBP'') has issued a final determination concerning the country of origin of a... determination that the U.S. is the country of origin of the patient transport chair for purposes of U.S... B), CBP issued a final determination concerning the country of origin of the BREEZ patient...

  20. Galilean conformal and superconformal symmetries

    SciTech Connect

    Lukierski, J.

    2012-10-15

    Firstly we discuss briefly three different algebras named as nonrelativistic (NR) conformal: Schroedinger, Galilean conformal, and infinite algebra of local NR conformal isometries. Further we shall consider in some detail Galilean conformal algebra (GCA) obtained in the limit c{yields}{infinity} from relativistic conformal algebraO(d+1, 2) (d-number of space dimensions). Two different contraction limits providing GCA and some recently considered realizations will be briefly discussed. Finally by considering NR contraction of D = 4 superconformal algebra the Galilei conformal superalgebra (GCSA) is obtained, in the formulation using complexWeyl supercharges.

  1. Effect of a suspension seat support chair on the trunk flexion angle and gluteal pressure during computer work

    PubMed Central

    Yoo, Won-gyu

    2015-01-01

    [Purpose] We assessed the effects of a suspension seat support chair on the trunk flexion angle and gluteal pressure during computer work. [Subjects] Ten males were recruited. [Methods] The suspension seat support was developed to prevent abnormal gluteal pressure and a slumped sitting posture during computer work. The gluteal pressure was measured with a TekScan system and the trunk flexion angle was measured with a video camera, to compare the differences between a general chair and the suspension seat support. [Results] The gluteal peak pressures were decreased significantly in the suspension seat support versus the general chair. The trunk flexion angle was also decreased significantly in the suspension seat support compared with the general chair. [Conclusions] This study suggests that the suspension seat support chair contributes to preventing abnormal gluteal pressure and a slumped sitting posture. PMID:26504341

  2. Multiscale conformal pattern transfer

    PubMed Central

    Lodewijks, Kristof; Miljkovic, Vladimir; Massiot, Inès; Mekonnen, Addis; Verre, Ruggero; Olsson, Eva; Dmitriev, Alexandre

    2016-01-01

    We demonstrate a method for seamless transfer from a parent flat substrate of basically any lithographic top-down or bottom-up pattern onto essentially any kind of surface. The nano- or microscale patterns, spanning macroscopic surface areas, can be transferred with high conformity onto a large variety of surfaces when such patterns are produced on a thin carbon film, grown on top of a sacrificial layer. The latter allows lifting the patterns from the flat parent substrate onto a water-air interface to be picked up by the host surface of choice. We illustrate the power of this technique by functionalizing broad range of materials including glass, plastics, metals, rough semiconductors and polymers, highlighting the potential applications in in situ colorimetry of the chemistry of materials, anti-counterfeit technologies, biomolecular and biomedical studies, light-matter interactions at the nanoscale, conformal photovoltaics and flexible electronics. PMID:27329824

  3. Multiscale conformal pattern transfer

    NASA Astrophysics Data System (ADS)

    Lodewijks, Kristof; Miljkovic, Vladimir; Massiot, Inès; Mekonnen, Addis; Verre, Ruggero; Olsson, Eva; Dmitriev, Alexandre

    2016-06-01

    We demonstrate a method for seamless transfer from a parent flat substrate of basically any lithographic top-down or bottom-up pattern onto essentially any kind of surface. The nano- or microscale patterns, spanning macroscopic surface areas, can be transferred with high conformity onto a large variety of surfaces when such patterns are produced on a thin carbon film, grown on top of a sacrificial layer. The latter allows lifting the patterns from the flat parent substrate onto a water-air interface to be picked up by the host surface of choice. We illustrate the power of this technique by functionalizing broad range of materials including glass, plastics, metals, rough semiconductors and polymers, highlighting the potential applications in in situ colorimetry of the chemistry of materials, anti-counterfeit technologies, biomolecular and biomedical studies, light-matter interactions at the nanoscale, conformal photovoltaics and flexible electronics.

  4. Multiscale conformal pattern transfer.

    PubMed

    Lodewijks, Kristof; Miljkovic, Vladimir; Massiot, Inès; Mekonnen, Addis; Verre, Ruggero; Olsson, Eva; Dmitriev, Alexandre

    2016-01-01

    We demonstrate a method for seamless transfer from a parent flat substrate of basically any lithographic top-down or bottom-up pattern onto essentially any kind of surface. The nano- or microscale patterns, spanning macroscopic surface areas, can be transferred with high conformity onto a large variety of surfaces when such patterns are produced on a thin carbon film, grown on top of a sacrificial layer. The latter allows lifting the patterns from the flat parent substrate onto a water-air interface to be picked up by the host surface of choice. We illustrate the power of this technique by functionalizing broad range of materials including glass, plastics, metals, rough semiconductors and polymers, highlighting the potential applications in in situ colorimetry of the chemistry of materials, anti-counterfeit technologies, biomolecular and biomedical studies, light-matter interactions at the nanoscale, conformal photovoltaics and flexible electronics. PMID:27329824

  5. Conformal gripping device

    NASA Technical Reports Server (NTRS)

    Vranish, John M. (Inventor)

    2009-01-01

    The present invention relates to a conformal gripping device. In an embodiment of the present invention a conformal gripper device may be disclosed comprising a frame that includes an array of movable pins. The device may also include a roller locking and unlocking system within the frame. The system may comprise a pair of locking rollers for each row of gripper pins to facilitate locking and unlocking the array of gripper pins on a column-by-column basis. The system may also include a striker element that may force the locking rollers to roll along an angled roll surface to facilitate unlocking of the array of pins on a column-by-column basis. The system may further include an electromagnetic actuator or solenoid and permanent magnets to facilitate movement of the striker element and the locking rollers.

  6. Conformational flexibility of aspartame.

    PubMed

    Toniolo, Claudio; Temussi, Pierandrea

    2016-05-01

    L-Aspartyl-L-phenylalanine methyl ester, better known as aspartame, is not only one of the most used artificial sweeteners, but also a very interesting molecule with respect to the correlation between molecular structure and taste. The extreme conformational flexibility of this dipeptide posed a huge difficulty when researchers tried to use it as a lead compound to design new sweeteners. In particular, it was difficult to take advantage of its molecular model as a mold to infer the shape of the, then unknown, active site of the sweet taste receptor. Here, we follow the story of the 3D structural aspects of aspartame from early conformational studies to recent docking into homology models of the receptor. © 2016 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 376-384, 2016. PMID:27038223

  7. The conformal bootstrap

    NASA Astrophysics Data System (ADS)

    Poland, David; Simmons-Duffin, David

    2016-06-01

    The conformal bootstrap was proposed in the 1970s as a strategy for calculating the properties of second-order phase transitions. After spectacular success elucidating two-dimensional systems, little progress was made on systems in higher dimensions until a recent renaissance beginning in 2008. We report on some of the main results and ideas from this renaissance, focusing on new determinations of critical exponents and correlation functions in the three-dimensional Ising and O(N) models.

  8. Conformal scalar field wormholes

    NASA Technical Reports Server (NTRS)

    Halliwell, Jonathan J.; Laflamme, Raymond

    1989-01-01

    The Euclidian Einstein equations with a cosmological constant and a conformally coupled scalar field are solved, taking the metric to be of the Robertson-Walker type. In the case Lambda = 0, solutions are found which represent a wormhole connecting two asymptotically flat Euclidian regions. In the case Lambda greater than 0, the solutions represent tunneling from a small Tolman-like universe to a large Robertson-Walker universe.

  9. Conformations of organophosphine oxides

    DOE PAGESBeta

    De Silva, Nuwan; Zahariev, Federico; Hay, Benjamin P.; Gordon, Mark S.; Windus, Theresa L.

    2015-07-17

    The conformations of a series of organophosphine oxides, OP(CH3)2R, where R = methyl, ethyl, isopropyl, tert-butyl, vinyl, and phenyl, are predicted using the MP2/cc-pVTZ level of theory. Comparison of potential energy surfaces for rotation about P–C bonds with crystal structure data reveals a strong correlation between predicted location and energetics of minima and histograms of dihedral angle distributions observed in the solid state. In addition, the most stable conformers are those that minimize the extent of steric repulsion between adjacent rotor substituents, and the torsional barriers tend to increase with the steric bulk of the rotating alkyl group. MM3 forcemore » field parameters were adjusted to fit the MP2 results, providing a fast and accurate model for predicting organophosphine oxides shapes—an essential part of understanding the chemistry of these compounds. As a result, the predictive power of the modified MM3 model was tested against MP2/cc-pVTZ conformations for triethylphosphine oxide, OP(CH2CH3)3, and triphenylphosphine oxide, OP(Ph)3.« less

  10. Conformations of organophosphine oxides

    SciTech Connect

    De Silva, Nuwan; Zahariev, Federico; Hay, Benjamin P.; Gordon, Mark S.; Windus, Theresa L.

    2015-07-17

    The conformations of a series of organophosphine oxides, OP(CH3)2R, where R = methyl, ethyl, isopropyl, tert-butyl, vinyl, and phenyl, are predicted using the MP2/cc-pVTZ level of theory. Comparison of potential energy surfaces for rotation about P–C bonds with crystal structure data reveals a strong correlation between predicted location and energetics of minima and histograms of dihedral angle distributions observed in the solid state. In addition, the most stable conformers are those that minimize the extent of steric repulsion between adjacent rotor substituents, and the torsional barriers tend to increase with the steric bulk of the rotating alkyl group. MM3 force field parameters were adjusted to fit the MP2 results, providing a fast and accurate model for predicting organophosphine oxides shapes—an essential part of understanding the chemistry of these compounds. As a result, the predictive power of the modified MM3 model was tested against MP2/cc-pVTZ conformations for triethylphosphine oxide, OP(CH2CH3)3, and triphenylphosphine oxide, OP(Ph)3.

  11. Hot conformal gauge theories

    NASA Astrophysics Data System (ADS)

    Mojaza, Matin; Pica, Claudio; Sannino, Francesco

    2010-12-01

    We compute the nonzero temperature free energy up to the order g6ln⁡(1/g) in the coupling constant for vectorlike SU(N) gauge theories featuring matter transforming according to different representations of the underlying gauge group. The number of matter fields, i.e. flavors, is arranged in such a way that the theory develops a perturbative stable infrared fixed point at zero temperature. Because of large distance conformality we trade the coupling constant with its fixed point value and define a reduced free energy which depends only on the number of flavors, colors, and matter representation. We show that the reduced free energy changes sign, at the second, fifth, and sixth order in the coupling, when decreasing the number of flavors from the upper end of the conformal window. If the change in sign is interpreted as a signal of an instability of the system then we infer a critical number of flavors. Surprisingly this number, if computed to the order g2, agrees with previous predictions for the lower boundary of the conformal window for nonsupersymmetric gauge theories. The higher order results tend to predict a higher number of critical flavors. These are universal properties, i.e. they are independent of the specific matter representation.

  12. Conformal superalgebras via tractor calculus

    NASA Astrophysics Data System (ADS)

    Lischewski, Andree

    2015-01-01

    We use the manifestly conformally invariant description of a Lorentzian conformal structure in terms of a parabolic Cartan geometry in order to introduce a superalgebra structure on the space of twistor spinors and normal conformal vector fields formulated in purely algebraic terms on parallel sections in tractor bundles. Via a fixed metric in the conformal class, one reproduces a conformal superalgebra structure that has been considered in the literature before. The tractor approach, however, makes clear that the failure of this object to be a Lie superalgebra in certain cases is due to purely algebraic identities on the spinor module and to special properties of the conformal holonomy representation. Moreover, it naturally generalizes to higher signatures. This yields new formulas for constructing new twistor spinors and higher order normal conformal Killing forms out of existing ones, generalizing the well-known spinorial Lie derivative. Moreover, we derive restrictions on the possible dimension of the space of twistor spinors in any metric signature.

  13. Improvement of the Chairs in Classrooms for Better Sitting Posture of Children

    NASA Astrophysics Data System (ADS)

    Ishihara, Keiko; Dake, Kazuo; Ishihara, Shigekazu

    2010-10-01

    We sought to improve the sitting postures of children studying in the classrooms of a primary school. We made the seat of a standard chair lower and attached a cushion designed by one of the authors. The cushion is cut at a 25° downward angle toward the legs to allow the users to support their weight with their feet and alleviate pressure on the underside of the thighs. We also lowered the desktop to below the height of children's elbows. Eighty-three children were given the new chairs and desks, and they were observed over 7 months. Around 10% of them voluntarily maintained good sitting postures; others straightened their postures when the teachers reminded them to do so.

  14. Development of a Virtual Presence Sharing System Using a Telework Chair

    NASA Astrophysics Data System (ADS)

    Ishii, Yutaka; Watanabe, Tomio

    There has been much discussion on remote communication support for a telework that will enable employees to work at remote offices. We have already developed a remote communication support system via embodied avatars based on users’ behaviors. However, there are various problems associated with an avatar-mediated interaction, particularly with regard to the relation between users and their avatars. In this study, we propose the concept of a presence sharing system Ghatcha [GHost Avatar on a Telework CHAir] in which the users’ embodiment is not indicated by the avatars but by the chairs that suggest the presence of avatars. This system provides the same communication space for the users’ embodiment, thus creating a feeling of working alongside remote workers. Moreover, the effectiveness of the prototype system is confirmed in the experiment.

  15. Career development resource: educational leadership in a department of surgery: vice chairs for education.

    PubMed

    Sanfey, Hilary; Boehler, Margaret; DaRosa, Debra; Dunnington, Gary L

    2012-07-01

    The growing appreciation of the need to adopt an evidence-based approach to teaching and assessment has led to a demand for faculty who are well versed in best practices in education. Surgeons with interest and expertise in instruction, curriculum development, educational research, and evaluation can have an important impact on the educational mission of a department of surgery. The increased fervor for accountability in education together with the challenges imposed by accreditation agencies and hospitals has made educational leadership responsibilities more time consuming and complex. In response to this, an increasing number of department chairs created Vice Chair for Education positions to support clerkship and program directors and ensure the department's education mission statement is fulfilled. PMID:22704712

  16. OSI Conformance Testing for Bibliographic Applications.

    ERIC Educational Resources Information Center

    Arbez, Gilbert; Swain, Leigh

    1990-01-01

    Describes the development of Open Systems Interconnection (OSI) conformance testing sites, conformance testing tools, and conformance testing services. Discusses related topics such as interoperability testing, arbitration testing, and international harmonization of conformance testing. A glossary is included. (24 references) (SD)

  17. Sinusoidal rotatory chair system by an auto-tuning fuzzy PID controller

    SciTech Connect

    Park, H.A.; Cha, I.S.; Baek, H.L.

    1995-12-31

    This paper presents DC servo motor speed control characteristics by fuzzy logic controller and considers position following control response with controller. A sinusoidal rotatory chair system using an auto tuning fuzzy PID control was designed to evaluate the vestibular function. Then the system is investigated for the effects of change by the fuzziness of fuzzy variable. If this system is supported by a channel, it is considered for application in industry of multi joint robot and precision parallel driving.

  18. Leaf growth is conformal.

    PubMed

    Alim, Karen; Armon, Shahaf; Shraiman, Boris I; Boudaoud, Arezki

    2016-01-01

    Growth pattern dynamics lie at the heart of morphogenesis. Here, we investigate the growth of plant leaves. We compute the conformal transformation that maps the contour of a leaf at a given stage onto the contour of the same leaf at a later stage. Based on the mapping we predict the local displacement field in the leaf blade and find it to agree with the experimentally measured displacement field to 92%. This approach is applicable to any two-dimensional system with locally isotropic growth, enabling the deduction of the whole growth field just from observation of the tissue contour. PMID:27597439

  19. Metamaterials with conformational nonlinearity

    NASA Astrophysics Data System (ADS)

    Lapine, Mikhail; Shadrivov, Ilya V.; Powell, David A.; Kivshar, Yuri S.

    2011-11-01

    Within a decade of fruitful development, metamaterials became a prominent area of research, bridging theoretical and applied electrodynamics, electrical engineering and material science. Being man-made structures, metamaterials offer a particularly useful playground to develop interdisciplinary concepts. Here we demonstrate a novel principle in metamaterial assembly which integrates electromagnetic, mechanical, and thermal responses within their elements. Through these mechanisms, the conformation of the meta-molecules changes, providing a dual mechanism for nonlinearity and offering nonlinear chirality. Our proposal opens a wide road towards further developments of nonlinear metamaterials and photonic structures, adding extra flexibility to their design and control.

  20. [Creation of the first university chair in psychiatry: Johann Christian August Heinroth in Leipzig].

    PubMed

    Steinberg, H

    2004-03-01

    Much research has been done on the work of the alleged "psychicist" Johann Christian August Heinroth (1773-1843). However, his academic career has not yet been investigated in depth. For the first time, original archive material and other sources are quoted to illuminate his history and that of the first European chair of psychiatry at Leipzig University in Germany. Heinroth was first appointed associate professor (without a specific subject), and on 21 October 1811 he became the first associate professor of "psychic therapy". Despite his efforts, this chair was not transformed into a fellow professorship in 1815. In 1819, Heinroth succeeded in being appointed fellow professor, but for medicine in general and not psychiatry in particular. Thus his position was upgraded but his subject was not. After Heinroth's death in 1843, Justus Radius (1797-1884) took over psychiatry as a third, "part-time" chair. After several shifts in responsibilities, he ceased being explicitly referred to as professor of psychiatry. PMID:15021930

  1. Child and adolescent psychiatry in general children's hospitals. A survey of chairs of psychiatry.

    PubMed

    Campo, J V; Kingsley, R S; Bridge, J; Mrazek, D

    2000-01-01

    This article characterizes the academic, administrative, clinical service, and fiscal characteristics of departments of psychiatry in traditional children's hospitals to determine the characteristics of fiscally successful programs. A survey of chairs of psychiatry from short-term general children's hospitals was conducted based on 38 questions addressing the descriptive characteristics of their respective departments. The characteristics of psychiatry programs identified as fiscally successful were compared to those of programs that required subsidy. Nine of 45 eligible children's hospitals (20%) did not have a department or section of psychiatry, and surveys were returned by 35 of 36 department chairs (97% response). Considerable variation exists in the academic, administrative, clinical services, and fiscal characteristics of programs, although over half are operating at a deficit. Fiscal success was associated with availability of inpatient and intermediate levels of psychiatric care, better integration of the psychiatry program within the children's hospital, and adequate fiscal information being provided to the psychiatry chair. Additional research regarding the potential of psychiatric services to generate clinical success and cost savings is warranted. Pediatric health care professionals and third-party payers should be educated regarding the relevance of psychiatric services within children's hospitals and in physically ill children. PMID:10749950

  2. Effects of chair restraint on the strength of the tibia in rhesus monkeys

    NASA Technical Reports Server (NTRS)

    Hutchinson, T. M.; Bakulin, A. V.; Rakhmanov, A. S.; Martin, R. B.; Steele, C. R.; Arnaud, S. B.

    2001-01-01

    To determine the effects of the relative inactivity and unloading on the strength of the tibias of monkeys, Macaca mulatta, we used a non-invasive test to measure bending stiffness, or EI (Nm2), a mechanical property. The technique was validated by comparisons of in vivo measurements with standard measures of EI in the same bones post-mortem (r2 = 0.95, P < 0.0001). Inter-test precision was 4.28+/-1.4%. Normative data in 24 monkeys, 3.0+/-0.7 years and 3.6+/-0.6 kg, revealed EI to be 16% higher in the right than left tibia (4.4+/-1.6 vs. 3.7+/-1.6 Nm2, P < 0.05). Five monkeys, restrained in chairs for 14 days, showed decreases in EI. There were no changes in EI in two chaired monkeys that lost weight during a 2-week space flight. The factors that account for both the decreases in bone mechanical properties after chair restraint at 1 g and lack of change after microgravity remain to be identified. Metabolic factors associated with body weight changes are suggested by our results.

  3. Repositioning chairs in benign paroxysmal positional vertigo: implications and clinical outcome.

    PubMed

    West, Niels; Hansen, Søren; Møller, Martin Nue; Bloch, Sune Land; Klokker, Mads

    2016-03-01

    The objective was to evaluate the clinical value of repositioning chairs in management of refractory benign paroxysmal positional vertigo (BPPV) and to study how different BPPV subtypes respond to treatment. We performed a retrospective chart review of 150 consecutive cases with refractory vertigo referred to our clinic within a 10-month period. The BPPV patients were managed with classical manual manoeuvres, the Epley Omniax(®) rotator (EO) or the TRV chair (TRV). In addition, a comprehensive review of the literature was performed. BPPV was identified in 95 cases. The number of needed treatments for posterior canalolithiasis versus posterior cupulolithiasis, horizontal cupulolithiasis and multi-canal affection was significant (p < 0.01). Thirty-seven (38 %) patients required only one repositioning manoeuvre and the overall symptom relief was 91.7-100 % after 3 treatments. Eleven patients (12 %) experienced relapse within the ½-year follow-up period. Horizontal cupulolithiasis and multi-canal affection constituted the most resilient cases. The literature search identified 9 repositioning chair studies. The EO and the TRV are highly valuable assets in diagnosis and management of BPPV of particularly complex and refractory cases. However, further validation is anticipated through controlled clinical trials. PMID:25749489

  4. Fluid shifts and endocrine responses during chair rest and water immersion in man

    NASA Technical Reports Server (NTRS)

    Greenleaf, J. E.; Shvartz, E.; Kravik, S.; Keil, L. C.

    1980-01-01

    The effects of external water pressure on intercompartmental fluid volume shifts and endocrine responses in man are investigated. Extracellular fluid volumes and plasma and urine electrolyte and endocrine responses of four male subjects were measured during eight hours of head-out water immersion and 16 hours of recovery bed rest and compared to responses obtained during eight hours of chair rest and 16 hours of bed rest without external hydrostatic pressure obtained in the same subjects five months later. Immersion is found to result in a substantial diuresis with respect to chair rest, accounted for by decreases in extracellular volume. A negative water balance during immersion and a positive water balance during chair rest were observed to be accompanied by a shift of extracellular volume to the intracellular compartment, as well as the suppression of plasma arginine vasopressin and renin activities in both regimes. The vasopressin and renin activity decreases are attributed to the increased central blood volume, and half of the plasma loss in immersed subjects is attributed to the effects of external water pressure.

  5. Conformations of [(R,R)-1,5-diaza-cis-decalin] copper (II) complex and its hydrogen bonding interaction with the crystal water: A combined experimental VA, UV-Vis and ECD spectroscopic and DFT study

    NASA Astrophysics Data System (ADS)

    Dezhahang, Zahra; Poopari, Mohammad Reza; Xu, Yunjie

    2012-09-01

    Chiral 1,5-diaza-cis-decalin ligand and its copper-complexes have found considerable applications in catalyzing enantioselective organic reactions. In the present article, (R,R)-1,5-diaza-cis-decalin ligand and its copper (II) hydroxide iodine hydrate complex have been investigated by using vibrational absorption (VA), ultraviolet-visible (UV-Vis), and electronic circular dichroism (ECD) experimental spectroscopic measurements, as well as density functional theory modeling. An extensive theoretical conformational analysis of the ligand has revealed that the ligand can adopt a good number of orientations in terms of its frame conformations, i.e. Chair-Chair, Chair-Boat, and Boat-Boat, the proximal (also denoted as in) and distal (out) positions for its two N atoms, and the equatorial (e) and axial (a) positions of its two amine H atoms. The most dominant conformation at room temperature was predicted to take on the Chair-Chair N-in H-ea configuration, based on the relative Gibbs free energy ordering at the B3LYP/6-31++G(d,p) level. The VA, vibrational CD, UV-Vis, and ECD spectra of the ligand conformers have been simulated. Conformational searches have also been carried out for the titled copper complex at the B3LYP/LanL2DZ level and the dominant conformer was predicted to have the Chair-Chair N-in H-ee configuration for its ligands, with a close to 100% Boltzmann population factor at room temperature. Furthermore, geometry optimizations and spectral simulations have been performed for the hydrogen bonded cluster of the complex with the crystal water. The effects of hydrogen bonding interaction with the crystal water on the VA, VCD, UV-Vis, and ECD spectra have been discussed. The interaction with the water molecule has been found to have significant impacts on the appearance of VA, VCD and ECD spectra and its inclusion is essential to obtain satisfactory interpretations of the experimental VA and ECD spectra.

  6. Conformally symmetric traversable wormholes

    SciTech Connect

    Boehmer, Christian G.; Harko, Tiberiu; Lobo, Francisco S. N.

    2007-10-15

    Exact solutions of traversable wormholes are found under the assumption of spherical symmetry and the existence of a nonstatic conformal symmetry, which presents a more systematic approach in searching for exact wormhole solutions. In this work, a wide variety of solutions are deduced by considering choices for the form function, a specific linear equation of state relating the energy density and the pressure anisotropy, and various phantom wormhole geometries are explored. A large class of solutions impose that the spatial distribution of the exotic matter is restricted to the throat neighborhood, with a cutoff of the stress-energy tensor at a finite junction interface, although asymptotically flat exact solutions are also found. Using the 'volume integral quantifier', it is found that the conformally symmetric phantom wormhole geometries may, in principle, be constructed by infinitesimally small amounts of averaged null energy condition violating matter. Considering the tidal acceleration traversability conditions for the phantom wormhole geometry, specific wormhole dimensions and the traversal velocity are also deduced.

  7. Eikonalization of conformal blocks

    SciTech Connect

    Fitzpatrick, A. Liam; Kaplan, Jared; Walters, Matthew T.; Wang, Junpu

    2015-09-03

    Classical field configurations such as the Coulomb potential and Schwarzschild solution are built from the t-channel exchange of many light degrees of freedom. We study the CFT analog of this phenomenon, which we term the 'eikonalization' of conformal blocks. We show that when an operator T appears in the OPE Ο(x)Ο(0), then the large spin Fock space states [TT···T] also appear in this OPE with a computable coefficient. The sum over the exchange of these Fock space states in an correlator build the classical 'T field' in the dual AdS description. In some limits the sum of all Fock space exchanges can be represented as the exponential of a single T exchange in the 4-pt correlator of O. Our results should be useful for systematizing 1/ℓ perturbation theory in general CFTs and simplifying the computation of large spin OPE coefficients. As examples we obtain the leading log ℓ dependence of Fock space conformal block coefficients, and we directly compute the OPE coefficients of the simplest ‘triple-trace’ operators.

  8. Eikonalization of conformal blocks

    DOE PAGESBeta

    Fitzpatrick, A. Liam; Kaplan, Jared; Walters, Matthew T.; Wang, Junpu

    2015-09-03

    Classical field configurations such as the Coulomb potential and Schwarzschild solution are built from the t-channel exchange of many light degrees of freedom. We study the CFT analog of this phenomenon, which we term the 'eikonalization' of conformal blocks. We show that when an operator T appears in the OPE Ο(x)Ο(0), then the large spin Fock space states [TT···T]ℓ also appear in this OPE with a computable coefficient. The sum over the exchange of these Fock space states in an correlator build the classical 'T field' in the dual AdS description. In some limits the sum of all Fock spacemore » exchanges can be represented as the exponential of a single T exchange in the 4-pt correlator of O. Our results should be useful for systematizing 1/ℓ perturbation theory in general CFTs and simplifying the computation of large spin OPE coefficients. As examples we obtain the leading log ℓ dependence of Fock space conformal block coefficients, and we directly compute the OPE coefficients of the simplest ‘triple-trace’ operators.« less

  9. 76 FR 35007 - Notice of Issuance of Final Determination Concerning the Country of Origin of Certain Office Chairs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... components. The components from China of the SAYL chairs include: casters, tilt assembly, cylinder, arm... liner may be sewn into the back side of the cover. A button hole also is sewn into the back side of...

  10. Recent Advances in Conformal Gravity

    NASA Astrophysics Data System (ADS)

    O'Brien, James; Chaykov, Spasen

    2016-03-01

    In recent years, significant advances have been made in alternative gravitational theories. Although MOND remains the leading candidate among the alternative models, Conformal Gravity has been studied by Mannheim and O'Brien to solve the rotation curve problem without the need for dark matter. Recently, Mannheim, O'Brien and Chaykov have begun solving other gravitational questions in Conformal Gravity. In this presentation, we highlight the new work of Conformal Gravity's application to random motions of clusters (the original Zwicky problem), gravitational bending of light, gravitational lensing and a very recent survey of dwarf galaxy rotation curves. We will show in each case that Conformal Gravity can provide an accurate explanation and prediction of the data without the need for dark matter. Coupled with the fact that Conformal Gravity is a fully re-normalizable metric theory of gravity, these results help to push Conformal Gravity onto a competitive stage against other alternative models.

  11. Structural, conformational and pharmacological study of some amides derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9 β-amine as potential analgesics

    NASA Astrophysics Data System (ADS)

    Iriepa, I.; Gil-Alberdi, B.; Gálvez, E.; Herranz, M. J.; Bellanato, J.; Carmona, P.; Orjales, A.; Berisa, A.; Labeaga, L.

    1999-05-01

    A series of amides derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9 β-amine were synthesized and studied by IR, Raman, 1H and 13C NMR spectroscopy. The compounds studied displayed in CDCl 3 a preferred flattened chair-chair conformation. IR (at room and variable temperature) and 1H and 13C NMR data showed the presence of an intramolecular NH⋯N-heterocyclic hydrogen bond in the pirazine derivative ( IV). Pharmacological assays on mice were drawn to evaluate drug-induced behavioral alteration peripheral or central acute toxicity and analgesic activity.

  12. Conformal Gravity and Gravitational Waves

    NASA Astrophysics Data System (ADS)

    Fabbri, Luca; Paranjape, M. B.

    We consider monochromatic, plane gravitational waves in a conformally invariant theory of general relativity. We show that the simple, standard ansatz for the metric, usually that which is taken for the linearized theory of these waves, is reducible to the metric of Minkowski spacetime via a sequence of conformal and coordinate transformations. This implies that we have in fact, exact plane wave solutions. However they are simply coordinate/conformal artifacts. As a consequence, they carry no energy.

  13. Killing and conformal Killing tensors

    NASA Astrophysics Data System (ADS)

    Heil, Konstantin; Moroianu, Andrei; Semmelmann, Uwe

    2016-08-01

    We introduce an appropriate formalism in order to study conformal Killing (symmetric) tensors on Riemannian manifolds. We reprove in a simple way some known results in the field and obtain several new results, like the classification of conformal Killing 2-tensors on Riemannian products of compact manifolds, Weitzenböck formulas leading to non-existence results, and construct various examples of manifolds with conformal Killing tensors.

  14. Effectiveness of a Batteryless and Wireless Wearable Sensor System for Identifying Bed and Chair Exits in Healthy Older People.

    PubMed

    Torres, Roberto Luis Shinmoto; Visvanathan, Renuka; Hoskins, Stephen; van den Hengel, Anton; Ranasinghe, Damith C

    2016-01-01

    Aging populations are increasing worldwide and strategies to minimize the impact of falls on older people need to be examined. Falls in hospitals are common and current hospital technological implementations use localized sensors on beds and chairs to alert caregivers of unsupervised patient ambulations; however, such systems have high false alarm rates. We investigate the recognition of bed and chair exits in real-time using a wireless wearable sensor worn by healthy older volunteers. Fourteen healthy older participants joined in supervised trials. They wore a batteryless, lightweight and wireless sensor over their attire and performed a set of broadly scripted activities. We developed a movement monitoring approach for the recognition of bed and chair exits based on a machine learning activity predictor. We investigated the effectiveness of our approach in generating bed and chair exit alerts in two possible clinical deployments (Room 1 and Room 2). The system obtained recall results above 93% (Room 2) and 94% (Room 1) for bed and chair exits, respectively. Precision was >78% and 67%, respectively, while F-score was >84% and 77% for bed and chair exits, respectively. This system has potential for real-time monitoring but further research in the final target population of older people is necessary. PMID:27092506

  15. Commentary: getting to the next phase in medical education--a role for the vice-chair for education.

    PubMed

    Pangaro, Louis N

    2012-08-01

    The author argues that a particular kind of departmental leadership is needed lest medical education become hostage both to distant management through regulatory metrics (which can displace local, institutional creativity) and to the financial pressures within the institution. Departmental chairs themselves have often been seen as barriers to successful integration and redesign of medical school curricula. The vice-chair for education is a critical figure in achieving this new kind of leadership.The author describes three forms of curriculum planning and management: phase 1, where the department chair makes the decisions; phase 2, dominated by regulation from above (in part a reaction to problems with the phase 1 approach); and phase 3, the author's vision of an approach in which decisions occur within departments but with an awareness of the institution as a collaborative system, and grounded in educational theory and research. The vice-chair for education would have a key role, carrying out interdepartmental planning and assessment for the chairs, who would provide them the needed time, training (in leadership and in educational theory and practice), support (from professional educators, with advanced degrees in education), and routes to academic advancement.Responding effectively to a complex and changing environment requires senior leaders at the middle-management level (such as vice-chairs for education) who are well trained in both the content of their specialties and also in interpersonal and collaborative skills, and who have the desire to reach a common future. PMID:22827983

  16. Effectiveness of a Batteryless and Wireless Wearable Sensor System for Identifying Bed and Chair Exits in Healthy Older People

    PubMed Central

    Shinmoto Torres, Roberto Luis; Visvanathan, Renuka; Hoskins, Stephen; van den Hengel, Anton; Ranasinghe, Damith C.

    2016-01-01

    Aging populations are increasing worldwide and strategies to minimize the impact of falls on older people need to be examined. Falls in hospitals are common and current hospital technological implementations use localized sensors on beds and chairs to alert caregivers of unsupervised patient ambulations; however, such systems have high false alarm rates. We investigate the recognition of bed and chair exits in real-time using a wireless wearable sensor worn by healthy older volunteers. Fourteen healthy older participants joined in supervised trials. They wore a batteryless, lightweight and wireless sensor over their attire and performed a set of broadly scripted activities. We developed a movement monitoring approach for the recognition of bed and chair exits based on a machine learning activity predictor. We investigated the effectiveness of our approach in generating bed and chair exit alerts in two possible clinical deployments (Room 1 and Room 2). The system obtained recall results above 93% (Room 2) and 94% (Room 1) for bed and chair exits, respectively. Precision was >78% and 67%, respectively, while F-score was >84% and 77% for bed and chair exits, respectively. This system has potential for real-time monitoring but further research in the final target population of older people is necessary. PMID:27092506

  17. Loop Virasoro Lie conformal algebra

    SciTech Connect

    Wu, Henan Chen, Qiufan; Yue, Xiaoqing

    2014-01-15

    The Lie conformal algebra of loop Virasoro algebra, denoted by CW, is introduced in this paper. Explicitly, CW is a Lie conformal algebra with C[∂]-basis (L{sub i} | i∈Z) and λ-brackets [L{sub i} {sub λ} L{sub j}] = (−∂−2λ)L{sub i+j}. Then conformal derivations of CW are determined. Finally, rank one conformal modules and Z-graded free intermediate series modules over CW are classified.

  18. Reflections on conformal spectra

    NASA Astrophysics Data System (ADS)

    Kim, Hyungrok; Kravchuk, Petr; Ooguri, Hirosi

    2016-04-01

    We use modular invariance and crossing symmetry of conformal field theory to reveal approximate reflection symmetries in the spectral decompositions of the partition function in two dimensions in the limit of large central charge and of the four-point function in any dimension in the limit of large scaling dimensions Δ0 of external operators. We use these symmetries to motivate universal upper bounds on the spectrum and the operator product expansion coefficients, which we then derive by independent techniques. Some of the bounds for four-point functions are valid for finite Δ0 as well as for large Δ0. We discuss a similar symmetry in a large spacetime dimension limit. Finally, we comment on the analogue of the Cardy formula and sparse light spectrum condition for the four-point function.

  19. Capturing Chromosome Conformation

    NASA Astrophysics Data System (ADS)

    Dekker, Job; Rippe, Karsten; Dekker, Martijn; Kleckner, Nancy

    2002-02-01

    We describe an approach to detect the frequency of interaction between any two genomic loci. Generation of a matrix of interaction frequencies between sites on the same or different chromosomes reveals their relative spatial disposition and provides information about the physical properties of the chromatin fiber. This methodology can be applied to the spatial organization of entire genomes in organisms from bacteria to human. Using the yeast Saccharomyces cerevisiae, we could confirm known qualitative features of chromosome organization within the nucleus and dynamic changes in that organization during meiosis. We also analyzed yeast chromosome III at the G1 stage of the cell cycle. We found that chromatin is highly flexible throughout. Furthermore, functionally distinct AT- and GC-rich domains were found to exhibit different conformations, and a population-average 3D model of chromosome III could be determined. Chromosome III emerges as a contorted ring.

  20. Conformations of 1-heptene secondary ozonide as studied by low temperature FT-IR spectroscopy

    NASA Astrophysics Data System (ADS)

    Bariseviciute, R.; Ceponkus, J.; Sablinskas, V.; Kimtys, L.

    2007-11-01

    Conformational diversity of the 1-heptene secondary ozonides (SOZ) in solid neat films as well as isolated in Ar or CO 2 matrices was studied by the means of FT-IR absorption spectroscopy. The ozonization reaction was performed at 77 K in the neat films of the reactants. The spectra of the ozonide were analyzed by combining the experimental data with the results of theoretical calculations performed at B3LYP 6-311++G (3df, 3pd) level. It was found that the samples of 1-heptene secondary ozonide exist as a mixture of three dominating conformers. The most stable conformer is the one with O-O half-chair configuration of the five membered ring, the aliphatic radical attached to the ring in equatorial position and the aliphatic chain being in gauche (∠OCCC ≈ -60°) position. The other two stable conformers are equatorial with aliphatic chain in anti (∠OCCC ≈ 180°) and gauche (∠OCCC ≈ 60°) positions. It was found from Van't Hoff plots that Δ H of the equatorial anti conformer is equal to 0.24 ± 0.03 kJ/mol. The experimental value of Δ H is in reasonable accordance to the calculated one - 0.5 kJ/mol.

  1. Molecular structure and conformational preferences of gaseous 1-iodo-1-silacyclohexane

    NASA Astrophysics Data System (ADS)

    Belyakov, A. V.; Baskakov, A. A.; Berger, R. J. F.; Mitzel, N. W.; Oberhammer, H.; Arnason, I.; Wallevik, S. Ò.

    2012-03-01

    The molecular structure of the axial and equatorial conformers of 1-iodo-1-silacyclohexane, CH2(CH2CH2)2SiH-I, as well as thermodynamic equilibrium between these species were investigated by means of gas-phase electron diffraction (GED) and quantum chemical calculations up to MP2(full)/SDB-AUG-CC-pVTZ level of theory (MP2). According to electron diffraction data, the vapor of this compound comprises a mixture of conformers with chair conformation and Cs symmetry differing in the axial and equatorial position of the Si-I bond (axial = 73(7) mol%/equatorial = 27(7) mol%) at T = 352 K. This corresponds to a free energy difference of A = -0.59(22) kcal mol-1. The observed gas-phase electron diffraction parameters are in good agreement with those obtained from theory. NBO analysis revealed that axial conformer of 1-iodo-1-silacyclohexane is an example for electrostatic stabilization of a conformer which is unfavorable in terms of steric and conjugation interaction.

  2. Replacement between conformity and counter-conformity in consumption decisions.

    PubMed

    Chou, Ting-Jui; Chang, En-Chung; Dai, Qi; Wong, Veronica

    2013-02-01

    This study assessed, in a Chinese context, how self-esteem interacts with perceived similarity and uniqueness to yield cognitive dissonance, and whether the dissonance leads to self-reported conformity or counter-conformity behavior. Participants were 408 respondents from 4 major Chinese cities (M age = 33.0 yr., SD = 4.3; 48% men). Self-perceptions of uniqueness, similarity, cognitive dissonance, self-esteem and need to behave in conformity or counter-conformity were measured. A theoretical model was assessed in four situations, relating the ratings of self-esteem and perceived similarity/uniqueness to the way other people at a wedding were dressed, and the resultant cognitive dissonance and conformity/ counter-conformity behavior. Regardless of high or low self-esteem, all participants reported cognitive dissonance when they were told that they were dressed extremely similarly to or extremely differently from the other people attending the wedding. However, the conforming/counter-conforming strategies used by participants to resolve the cognitive dissonance differed. When encountering dissonance induced by the perceived extreme uniqueness of dress, participants with low self-esteem tended to say they would dress next time so as to conform with the way others were dressed, while those with high self-esteem indicated they would continue their counter-conformity in attire. When encountering dissonance induced by the perceived extreme similarity to others, both those with high and low self-esteem tended to say they would dress in an unorthodox manner to surprise other people in the future. PMID:23654033

  3. Classical Virasoro irregular conformal block

    NASA Astrophysics Data System (ADS)

    Rim, Chaiho; Zhang, Hong

    2015-07-01

    Virasoro irregular conformal block with arbitrary rank is obtained for the classical limit or equivalently Nekrasov-Shatashvili limit using the beta-deformed irregular matrix model (Penner-type matrix model for the irregular conformal block). The same result is derived using the generalized Mathieu equation which is equivalent to the loop equation of the irregular matrix model.

  4. Conformal gravity and time

    NASA Astrophysics Data System (ADS)

    Hazboun, Jeffrey Shafiq

    2014-10-01

    Cartan geometry provides a rich formalism from which to look at various geometrically motivated extensions to general relativity. In this manuscript, we start by motivating reasons to extend the theory of general relativity. We then introduce the reader to our technique, called the quotient manifold method, for extending the geometry of spacetime. We will specifically look at the class of theories formed from the various quotients of the conformal group. Starting with the conformal symmetries of Euclidean space, we construct a manifold where time manifests as a part of the geometry. Though there is no matter present in the geome- try studied here, geometric terms analogous to dark energy and dark matter appear when we write down the Einstein tensor. Specifically, the quotient of the conformal group of Euclidean four-space by its Weyl subgroup results in a geometry possessing many of the properties of relativistic phase space, including both a natural symplectic form and nondegenerate Killing metric. We show the general solution possesses orthogonal Lagrangian submanifolds, with the induced metric and the spin connection on the submanifolds necessarily Lorentzian, despite the Euclidean starting point. By examining the structure equations of the biconformal space in an orthonormal frame adapted to its phase space properties, we also find two new tensor fields exist in this geometry, not present in Riemannian geometry. The first is a combination of the Weyl vector with the scale factor on the metric, and determines the time-like directions on the submanifolds. The second comes from the components of the spin connection, symmetric with respect to the new metric. Though this field comes from the spin connection, it transforms ho- mogeneously. Finally, we show in the absence of Cartan curvature or sources, the configuration space has geometric terms equivalent to a perfect fluid and a cosmological constant. We complete the analysis of this homogeneous space by

  5. Projectors, shadows, and conformal blocks

    NASA Astrophysics Data System (ADS)

    Simmons-Duffin, David

    2014-04-01

    We introduce a method for computing conformal blocks of operators in arbitrary Lorentz representations in any spacetime dimension, making it possible to apply bootstrap techniques to operators with spin. The key idea is to implement the "shadow formalism" of Ferrara, Gatto, Grillo, and Parisi in a setting where conformal invariance is manifest. Conformal blocks in d-dimensions can be expressed as integrals over the projective null-cone in the "embedding space" d+1,1. Taking care with their analytic structure, these integrals can be evaluated in great generality, reducing the computation of conformal blocks to a bookkeeping exercise. To facilitate calculations in four-dimensional CFTs, we introduce techniques for writing down conformally-invariant correlators using auxiliary twistor variables, and demonstrate their use in some simple examples.

  6. The Henry Cecil Ranson McBay Chair in Space Science

    NASA Technical Reports Server (NTRS)

    Bota, Kofi B.; King, James, Jr.

    1999-01-01

    The goals and objectives of the Henry Cecil Ransom McBay Chair in Space Sciences were to: (1) provide leadership in developing and expanding Space Science curriculum; (2) contribute to the research and education endeavors of NASA's Mission to Planet Earth program; (3) expand opportunities for education and hands-on research in Space and Earth Sciences; (4) enhance scientific and technological literacy at all educational levels and to increase awareness of opportunities in the Space Sciences; and (5) develop a pipeline, starting with high school, of African American students who will develop into a cadre of well-trained scientists with interest in Space Science Research and Development.

  7. Warped conformal field theory

    NASA Astrophysics Data System (ADS)

    Detournay, Stéphane; Hartman, Thomas; Hofman, Diego M.

    2012-12-01

    We study field theories in two spacetime dimensions invariant under a chiral scaling symmetry that acts only on right-movers. The local symmetries include one copy of the Virasoro algebra and a U(1) current algebra. This differs from the two-dimensional conformal group but in some respects is equally powerful in constraining the theory. In particular, the symmetries on a torus lead to modular covariance of the partition function, which is used to derive a universal formula for the asymptotic density of states. For an application we turn to the holographic description of black holes in quantum gravity, motivated by the fact that the symmetries in the near-horizon geometry of any extremal black hole are identical to those of a two-dimensional field theory with chiral scaling. We consider two examples: black holes in warped AdS3 in topologically massive gravity and in string theory. In both cases, the density of states in the two-dimensional field theory reproduces the Bekenstein-Hawking entropy of black holes in the gravity theory.

  8. Dynamics of protein conformations

    NASA Astrophysics Data System (ADS)

    Stepanova, Maria

    2010-10-01

    A novel theoretical methodology is introduced to identify dynamic structural domains and analyze local flexibility in proteins. The methodology employs a multiscale approach combining identification of essential collective coordinates based on the covariance analysis of molecular dynamics trajectories, construction of the Mori projection operator with these essential coordinates, and analysis of the corresponding generalized Langevin equations [M.Stepanova, Phys.Rev.E 76(2007)051918]. Because the approach employs a rigorous theory, the outcomes are physically transparent: the dynamic domains are associated with regions of relative rigidity in the protein, whereas off-domain regions are relatively soft. This also allows scoring the flexibility in the macromolecule with atomic-level resolution [N.Blinov, M.Berjanskii, D.S.Wishart, and M.Stepanova, Biochemistry, 48(2009)1488]. The applications include the domain coarse-graining and characterization of conformational stability in protein G and prion proteins. The results are compared with published NMR experiments. Potential applications for structural biology, bioinformatics, and drug design are discussed.

  9. Molecular mechanics approach for design and conformational studies of macrocyclic ligands

    NASA Astrophysics Data System (ADS)

    Rohini, Akbar, Rifat; Kanungo, B. K.

    2015-08-01

    Computational Chemistry has revolutionized way of viewing molecules at the quantum mechanical scale by allowing simulating various chemical scenarios that are not possible to study in a laboratory. The remarkable applications of computational chemistry have promoted to design and test of the effectiveness of various methods for searching the conformational space of highly flexible molecules. In this context, we conducted a series of optimization and conformational searches on macrocyclic based ligands, 9N3Me5Ox, (1,4,7-tris(5-methyl-8-hydroxyquinoline)-1,4,7-triazacyclononane) and 12N3Me5Ox, (1,5,9-tris(5-methyl-8-hydroxyquinoline)-1,5,9-triazacyclododecane) and studied their selectivity and coordination behavior with some lanthanide metal ions in molecular mechanics and semiempirical methods. The methods include both systematic and random conformational searches for dihedral angles, torsion angles and Cartesian coordinates. Structural studies were carried out by using geometry optimization, coordination scans and electronic properties were evaluated. The results clearly show that chair-boat conformational isomer of 9N3Me5Ox ligand is more stable due to lower eclipsing ethane interaction and form stronger adduct complexes with lanthanide metal ion. This is because of the fact that, in a central unit of 9N3 of the ligand form six endo type bonds out of nine. The rest of bonds have trans conformation. In contrast, for the adduct of 12N3Me5Ox, two C-C bonds have on eclipsed conformation, and others have synclinal and antiperiplanar confirmations. The distortion of the two eclipsed conformations may affect the yields and the stability of the complexes.

  10. Molecular mechanics approach for design and conformational studies of macrocyclic ligands

    SciTech Connect

    Rohini,; Akbar, Rifat; Kanungo, B. K.

    2015-08-28

    Computational Chemistry has revolutionized way of viewing molecules at the quantum mechanical scale by allowing simulating various chemical scenarios that are not possible to study in a laboratory. The remarkable applications of computational chemistry have promoted to design and test of the effectiveness of various methods for searching the conformational space of highly flexible molecules. In this context, we conducted a series of optimization and conformational searches on macrocyclic based ligands, 9N3Me5Ox, (1,4,7-tris(5-methyl-8-hydroxyquinoline)-1,4,7-triazacyclononane) and 12N3Me5Ox, (1,5,9-tris(5-methyl-8-hydroxyquinoline)-1,5,9-triazacyclododecane) and studied their selectivity and coordination behavior with some lanthanide metal ions in molecular mechanics and semiempirical methods. The methods include both systematic and random conformational searches for dihedral angles, torsion angles and Cartesian coordinates. Structural studies were carried out by using geometry optimization, coordination scans and electronic properties were evaluated. The results clearly show that chair-boat conformational isomer of 9N3Me5Ox ligand is more stable due to lower eclipsing ethane interaction and form stronger adduct complexes with lanthanide metal ion. This is because of the fact that, in a central unit of 9N3 of the ligand form six endo type bonds out of nine. The rest of bonds have trans conformation. In contrast, for the adduct of 12N3Me5Ox, two C-C bonds have on eclipsed conformation, and others have synclinal and antiperiplanar confirmations. The distortion of the two eclipsed conformations may affect the yields and the stability of the complexes.

  11. Towards conformal loop quantum gravity

    NASA Astrophysics Data System (ADS)

    H-T Wang, Charles

    2006-03-01

    A discussion is given of recent developments in canonical gravity that assimilates the conformal analysis of gravitational degrees of freedom. The work is motivated by the problem of time in quantum gravity and is carried out at the metric and the triad levels. At the metric level, it is shown that by extending the Arnowitt-Deser-Misner (ADM) phase space of general relativity (GR), a conformal form of geometrodynamics can be constructed. In addition to the Hamiltonian and Diffeomorphism constraints, an extra first class constraint is introduced to generate conformal transformations. This phase space consists of York's mean extrinsic curvature time, conformal three-metric and their momenta. At the triad level, the phase space of GR is further enlarged by incorporating spin-gauge as well as conformal symmetries. This leads to a canonical formulation of GR using a new set of real spin connection variables. The resulting gravitational constraints are first class, consisting of the Hamiltonian constraint and the canonical generators for spin-gauge and conformorphism transformations. The formulation has a remarkable feature of being parameter-free. Indeed, it is shown that a conformal parameter of the Barbero-Immirzi type can be absorbed by the conformal symmetry of the extended phase space. This gives rise to an alternative approach to loop quantum gravity that addresses both the conceptual problem of time and the technical problem of functional calculus in quantum gravity.

  12. Logarithmic conformal field theory

    NASA Astrophysics Data System (ADS)

    Gainutdinov, Azat; Ridout, David; Runkel, Ingo

    2013-12-01

    Conformal field theory (CFT) has proven to be one of the richest and deepest subjects of modern theoretical and mathematical physics research, especially as regards statistical mechanics and string theory. It has also stimulated an enormous amount of activity in mathematics, shaping and building bridges between seemingly disparate fields through the study of vertex operator algebras, a (partial) axiomatisation of a chiral CFT. One can add to this that the successes of CFT, particularly when applied to statistical lattice models, have also served as an inspiration for mathematicians to develop entirely new fields: the Schramm-Loewner evolution and Smirnov's discrete complex analysis being notable examples. When the energy operator fails to be diagonalisable on the quantum state space, the CFT is said to be logarithmic. Consequently, a logarithmic CFT is one whose quantum space of states is constructed from a collection of representations which includes reducible but indecomposable ones. This qualifier arises because of the consequence that certain correlation functions will possess logarithmic singularities, something that contrasts with the familiar case of power law singularities. While such logarithmic singularities and reducible representations were noted by Rozansky and Saleur in their study of the U (1|1) Wess-Zumino-Witten model in 1992, the link between the non-diagonalisability of the energy operator and logarithmic singularities in correlators is usually ascribed to Gurarie's 1993 article (his paper also contains the first usage of the term 'logarithmic conformal field theory'). The class of CFTs that were under control at this time was quite small. In particular, an enormous amount of work from the statistical mechanics and string theory communities had produced a fairly detailed understanding of the (so-called) rational CFTs. However, physicists from both camps were well aware that applications from many diverse fields required significantly more

  13. Characteristics of highly successful orthopedic surgeons: a survey of orthopedic chairs and editors

    PubMed Central

    Klein, Guy; Hussain, Nasir; Sprague, Sheila; Mehlman, Charles T.; Dogbey, Godwin; Bhandari, Mohit

    2013-01-01

    Background Highly successful orthopedic surgeons are a small group of individuals who exert a large influence on the orthopedic field. However, the characteristics of these leaders have not been well-described or studied. Methods Orthopedic surgeons who are departmental chairs, journal editors, editorial board members of the Journal of Bone and Joint Surgery (British edition), or current or past presidents of major orthopedic associations were invited to complete a survey designed to provide insight into their motivations, academic backgrounds and accomplishments, emotional and physical health, and job satisfaction. Results In all, 152 surgeons completed the questionnaire. We identified several characteristics of highly successful surgeons. Many have contributed prolific numbers of publications and book chapters and obtained considerable funding for research. They were often motivated by a “desire for personal development (interesting challenge, new opportunities),” whereas “relocating to a new institution, financial gain, or lack of alternative candidates” played little to no role in their decisions to take positions of leadership. Most respondents were happy with their specialty choice despite long hours and high levels of stress. Despite challenges to their time, successful orthopedic surgeons made a strong effort to maintain their health; compared with other physicians, they exercise more, are more likely to have a primary care physician and feel better physically. Conclusion Departmental chairs, journal editors and presidents of orthopedic associations cope with considerable demands of clinical, administrative, educational and research duties while maintaining a high level of health, happiness and job satisfaction. PMID:23706848

  14. Different Brain Responses to Pain and Its Expectation in the Dental Chair.

    PubMed

    Racek, A J; Hu, X; Nascimento, T D; Bender, M C; Khatib, L; Chiego, D; Holland, G R; Bauer, P; McDonald, N; Ellwood, R P; DaSilva, A F

    2015-07-01

    A dental appointment commonly prompts fear of a painful experience, yet we have never fully understood how our brains react to the expectation of imminent tooth pain once in a dental chair. In our study, 21 patients with hypersensitive teeth were tested using nonpainful and painful stimuli in a clinical setting. Subjects were tested in a dental chair using functional near-infrared spectroscopy to measure cortical activity during a stepwise cold stimulation of a hypersensitive tooth, as well as nonpainful control stimulation on the same tooth. Patients' sensory-discriminative and emotional-cognitive cortical regions were studied through the transition of a neutral to a painful stimulation. In the putative somatosensory cortex contralateral to the stimulus, 2 well-defined hemodynamic peaks were detected in the homuncular orofacial region: the first peak during the nonpainful phase and a second peak after the pain threshold was reached. Moreover, in the upper-left and lower-right prefrontal cortices, there was a significant active hemodynamic response in only the first phase, before the pain. Subsequently, the same prefrontal cortical areas deactivated after a painful experience had been reached. Our study indicates for the first time that pain perception and expectation elicit different hemodynamic cortical responses in a dental clinical setting. PMID:25904140

  15. A smart health monitoring chair for nonintrusive measurement of biological signals.

    PubMed

    Baek, Hyun Jae; Chung, Gih Sung; Kim, Ko Keun; Park, Kwang Suk

    2012-01-01

    We developed nonintrusive methods for simultaneous electrocardiogram, photoplethysmogram, and ballistocardiogram measurements that do not require direct contact between instruments and bare skin. These methods were applied to the design of a diagnostic chair for unconstrained heart rate and blood pressure monitoring purposes. Our methods were operationalized through capacitively coupled electrodes installed in the chair back that include high-input impedance amplifiers, and conductive textiles installed in the seat for capacitive driven-right-leg circuit configuration that is capable of recording electrocardiogram information through clothing. Photoplethysmograms were measured through clothing using seat mounted sensors with specially designed amplifier circuits that vary in light intensity according to clothing type. Ballistocardiograms were recorded using a film type transducer material, polyvinylidenefluoride (PVDF), which was installed beneath the seat cover. By simultaneously measuring signals, beat-to-beat heart rates could be monitored even when electrocardiograms were not recorded due to movement artifacts. Beat-to-beat blood pressure was also monitored using unconstrained measurements of pulse arrival time and other physiological parameters, and our experimental results indicated that the estimated blood pressure tended to coincide with actual blood pressure measurements. This study demonstrates the feasibility of our method and device for biological signal monitoring through clothing for unconstrained long-term daily health monitoring that does not require user awareness and is not limited by physical activity. PMID:22086543

  16. Are pressure measurements effective in the assessment of office chair comfort/discomfort? A review.

    PubMed

    Zemp, Roland; Taylor, William R; Lorenzetti, Silvio

    2015-05-01

    Nowadays, the majority of jobs in the western world involves sitting in an office chair. As a result, a comfortable and supported sitting position is essential for employees. In the literature, various objective methods (e.g. pressure measurements, measurements of posture, EMG etc.) have been used to assess sitting comfort/discomfort, but their validity remains unknown. This review therefore examines the relationship between subjective comfort/discomfort and pressure measurements while sitting in office chairs. The literature search resulted in eight papers that met all our requirements. Four studies identified a relationship between subjective comfort/discomfort and pressure distribution parameters (including correlations of up to r = 0.7 ± 0.13). However, the technique for evaluating subjective comfort/discomfort seems to play an important role on the results achieved, therefore placing their validity into question. The peak pressure on the seat pan, the pressure distribution on the backrest and the pressure pattern changes (seat pan and backrest) all appear to be reliable measures for quantifying comfort or discomfort. PMID:25683554

  17. Physiological Motion Axis for the Seat of a Dynamic Office Chair

    PubMed Central

    Kuster, Roman Peter; Bauer, Christoph Markus; Oetiker, Sarah; Kool, Jan

    2016-01-01

    Objective The aim of this study was to determine and verify the optimal location of the motion axis (MA) for the seat of a dynamic office chair. Background A dynamic seat that supports pelvic motion may improve physical well-being and decrease the risk of sitting-associated disorders. However, office work requires an undisturbed view on the work task, which means a stable position of the upper trunk and head. Current dynamic office chairs do not fulfill this need. Consequently, a dynamic seat was adapted to the physiological kinematics of the human spine. Method Three-dimensional motion tracking in free sitting helped determine the physiological MA of the spine in the frontal plane. Three dynamic seats with physiological, lower, and higher MA were compared in stable upper body posture (thorax inclination) and seat support of pelvic motion (dynamic fitting accuracy). Spinal kinematics during sitting and walking were compared. Results The physiological MA was at the level of the 11th thoracic vertebra, causing minimal thorax inclination and high dynamic fitting accuracy. Spinal motion in active sitting and walking was similar. Conclusion The physiological MA of the seat allows considerable lateral flexion of the spine similar to walking with a stable upper body posture and a high seat support of pelvic motion. Application The physiological MA enables lateral flexion of the spine, similar to walking, without affecting stable upper body posture, thus allowing active sitting while focusing on work. PMID:27150530

  18. Jean-Martin Charcot and his vibratory chair for Parkinson disease.

    PubMed

    Goetz, Christopher G

    2009-08-11

    Vibration therapy is currently used in diverse medical specialties ranging from orthopedics to urology to sports medicine. The celebrated 19th-century neurologist, J.-M. Charcot, used vibratory therapy to treat Parkinson disease (PD). This study analyzed printed writings by Charcot and other writers on vibratory therapy and accessed unpublished notes from the Salpêtrière Hospital, Paris. Charcot lectured on several occasions on vibratory therapy and its neurologic applications. He developed a vibration chair for patients with PD after he observed that patients were more comfortable and slept better after a train or carriage ride. He replicated this experience by having patients undergo daily 30-minute sessions in the automated vibratory chair (fauteuil trépidant). His junior colleague, Gilles de la Tourette, extended these observations and developed a helmet that vibrated the head on the premise that the brain responded directly to the pulsations. Although after Charcot's death vibratory therapy was not widely pursued, vibratory appliances are reemerging in 21st century medicine and can be retested using adaptations of Charcot's neurologic protocols. PMID:19667323

  19. Simulation of a Congress at the Chair of Biology II in Bioengineering

    NASA Astrophysics Data System (ADS)

    Naranjo, A. V.; Reznichenco, V.; López, N.; Hernández, R.; Bajinay, S.

    2007-11-01

    This work has been developed in the Chair of Biology II, the curricular contents of which correspond to Human Anatomy. This subject is taught in the second semester of the second year of studies in Bioengineering. Our main objective is that the students attending the course may integrate the syllabus contents of Anatomy with those of other subjects in the career. Ever since 1998 we have organized a congress named Congreso Intracátedra de Biología II (Intra Chair Congress on Biology II). This is the last assignment in the semester and is compulsory for regular students of the subject. It consists in simulating a scientific congress with international characteristics. The guidelines for the congress are made known to the students at the beginning of the semester. In groups of up to three members, the students must undertake a work that relates aspects of Anatomy with Bioengineering. Students are expected to investigate on diagnostic and/or therapeutic technology in order to write a paper that must be accepted in advance of the event. The presentation of the work must be made through PowerPoint. The originality of the research work done and the wide range of topics selected are surprising. Problems are tackled from the standpoints both of the various medical fields and of bioengineering despite the fact that they are just students of the second year in Bioengineering.

  20. CONFORMANCE IMPROVEMENT USING GELS

    SciTech Connect

    Randall S. Seright

    2002-02-28

    This technical progress report describes work performed from June 20 through December 19, 2001, for the project, ''Conformance Improvement Using Gels''. Interest has increased in some new polymeric products that purport to substantially reduce permeability to water while causing minimum permeability reduction to oil. In view of this interest, we are currently studying BJ's Aqua Con. Results from six corefloods revealed that the Aqua Con gelant consistently reduced permeability to water more than that to oil. However, the magnitude of the disproportionate permeability reduction varied significantly for the various experiments. Thus, as with most materials tested to date, the issue of reproducibility and control of the disproportionate permeability remains to be resolved. Concern exists about the ability of gels to resist washout after placement in fractures. We examined whether a width constriction in the middle of a fracture would cause different gel washout behavior upstream versus downstream of the constriction. Tests were performed using a formed Cr(III)-acetate-HPAM gel in a 48-in.-long fracture with three sections of equal length, but with widths of 0.08-, 0.02-, and 0.08-in., respectively. The pressure gradients during gel extrusion (i.e., placement) were similar in the two 0.08-in.-wide fracture sections, even though they were separated by a 0.02-in.-wide fracture section. The constriction associated with the middle fracture section may have inhibited gel washout during the first pulse of brine injection after gel placement. However, during subsequent phases of brine injection, the constriction did not inhibit washout in the upstream fracture section any more than in the downstream section.

  1. Synthesis, characterisation, conformational preferences, dynamic NMR studies and antimicrobial evaluation of N-nitroso- and N-formyl-c-3,t-3-dimethyl-r-2,c-7-diphenyl-1,4-diazepan-5-ones

    NASA Astrophysics Data System (ADS)

    Ponnuswamy, S.; Akila, A.; Kiruthiga devi, D.; Maheshwaran, V.; Ponnuswamy, M. N.

    2016-04-01

    The stereochemical preferences of N-nitroso- and N-formyl-c-3,t-3-dimethyl-r-2,c-7-diphenyl-1,4-diazepan-5-ones 3 & 4, respectively, have been determined using 1D and 2D NMR spectral techniques. Interestingly, the N-nitroso compound 3 is found to prefer an equilibrium between alternate chair conformations with diaxial phenyl groups, while the N-formyl compound 4 prefers flattened boat conformation. This is stereochemically a novel report on the flexible rings adopting a chair conformation with diaxial phenyl groups. The X-ray crystal structure of N-nitroso-c-3,t-3-dimethyl-r-2,c-7-diphenyl-1,4-diazepan-5-one (3) also supports the chair conformation with diaxial phenyl groups. Dynamic 1H NMR spectral studies have been carried out on the N-nitroso and N-formyl diazepan-5-ones 3 &4 and the energy barriers for N-NO and N-CO rotations are found to be 88.7 and 75.7 kJ/mol, respectively. The antimicrobial activities have been determined for the compounds 2-4 and it is found that all the compounds exhibit significant antibacterial and antifungal activities when compared to the standard chloramphenicol.

  2. Conformational changes of adsorbed proteins

    NASA Astrophysics Data System (ADS)

    Allen, Scott

    2005-03-01

    The adsorption of bovine serum albumin (BSA) and pepsin to gold surfaces has been studied using surface plasmon resonance (SPR). Proteins are adsorbed from solution onto a gold surface and changes in the conformation of the adsorbed proteins are induced by changing the buffer solution. We selected pH and ionic strength values for the buffer solutions that are known from our circular dichroism measurements to cause conformational changes of the proteins in bulk solution. We find that for both BSA and pepsin the changes in conformation are impeded by the interaction of the protein with the gold surface.

  3. Conformational Landscape of Nicotinoids: Solving the "conformational - Rity" of Anabasine

    NASA Astrophysics Data System (ADS)

    Lesarri, Alberto; Cocinero, Emilio J.; Evangelisti, Luca; Suenram, Richard D.; Caminati, Walther; Grabow, Jens-Uwe

    2010-06-01

    The conformational landscape of the alkaloid anabasine (neonicotine) has been investigated using rotational spectroscopy and ab initio calculations. The results allow a detailed comparison of the structural properties of the prototype piperidinic and pyrrolidinic nicotinoids (anabasine vs. nicotine). Anabasine adopts two most stable conformations in isolation conditions, for which we determined accurate rotational and nuclear quadrupole coupling parameters. The preferred conformations are characterized by an equatorial pyridine moiety and additional N-H equatorial stereochemistry at the piperidine ring (Eq-Eq). The two rings of anabasine are close to a bisecting arrangement, with the observed conformations differing in a ca. 180° rotation of the pyridine subunit, denoted either Syn or Anti. The preference of anabasine for the Eq-Eq-Syn conformation has been established by relative intensity measurements (Syn/Anti˜5(2)). The conformational preferences of free anabasine are directed by a N\\cdot\\cdot\\cdotH-C weak hydrogen bond interaction between the nitrogen lone pair at piperidine and the closest hydrogen bond in pyridine, with N\\cdot\\cdot\\cdotN distances ranging from 4.750 Å (Syn) to 4.233 Å (Anti). R. J. Lavrich, R. D. Suenram, D. F. Plusquellic and S. Davis, 58^th OSU Int. Symp. on Mol. Spectrosc., Columbus, OH, 2003, Comm. RH13.

  4. Logarithmic conformal field theory

    NASA Astrophysics Data System (ADS)

    Gainutdinov, Azat; Ridout, David; Runkel, Ingo

    2013-12-01

    Conformal field theory (CFT) has proven to be one of the richest and deepest subjects of modern theoretical and mathematical physics research, especially as regards statistical mechanics and string theory. It has also stimulated an enormous amount of activity in mathematics, shaping and building bridges between seemingly disparate fields through the study of vertex operator algebras, a (partial) axiomatisation of a chiral CFT. One can add to this that the successes of CFT, particularly when applied to statistical lattice models, have also served as an inspiration for mathematicians to develop entirely new fields: the Schramm-Loewner evolution and Smirnov's discrete complex analysis being notable examples. When the energy operator fails to be diagonalisable on the quantum state space, the CFT is said to be logarithmic. Consequently, a logarithmic CFT is one whose quantum space of states is constructed from a collection of representations which includes reducible but indecomposable ones. This qualifier arises because of the consequence that certain correlation functions will possess logarithmic singularities, something that contrasts with the familiar case of power law singularities. While such logarithmic singularities and reducible representations were noted by Rozansky and Saleur in their study of the U (1|1) Wess-Zumino-Witten model in 1992, the link between the non-diagonalisability of the energy operator and logarithmic singularities in correlators is usually ascribed to Gurarie's 1993 article (his paper also contains the first usage of the term 'logarithmic conformal field theory'). The class of CFTs that were under control at this time was quite small. In particular, an enormous amount of work from the statistical mechanics and string theory communities had produced a fairly detailed understanding of the (so-called) rational CFTs. However, physicists from both camps were well aware that applications from many diverse fields required significantly more

  5. Lattice Simulations and Infrared Conformality

    DOE PAGESBeta

    Appelquist, Thomas; Fleming, George T.; Lin, Meifeng; Neil, Ethan T.; Schaich, David A

    2011-09-01

    We examine several recent lattice-simulation data sets, asking whether they are consistent with infrared conformality. We observe, in particular, that for an SU(3) gauge theory with 12 Dirac fermions in the fundamental representation, recent simulation data can be described assuming infrared conformality. Lattice simulations include a fermion mass m which is then extrapolated to zero, and we note that this data can be fit by a small-m expansion, allowing a controlled extrapolation. We also note that the conformal hypothesis does not work well for two theories that are known or expected to be confining and chirally broken, and that itmore » does work well for another theory expected to be infrared conformal.« less

  6. Conformation Distributions in Adsorbed Proteins.

    NASA Astrophysics Data System (ADS)

    Meuse, Curtis W.; Hubbard, Joseph B.; Vrettos, John S.; Smith, Jackson R.; Cicerone, Marcus T.

    2007-03-01

    While the structural basis of protein function is well understood in the biopharmaceutical and biotechnology industries, few methods for the characterization and comparison of protein conformation distributions are available. New methods capable of measuring the stability of protein conformations and the integrity of protein-protein, protein-ligand and protein-surface interactions both in solution and on surfaces are needed to help the development of protein-based products. We are developing infrared spectroscopy methods for the characterization and comparison of molecular conformation distributions in monolayers and in solutions. We have extracted an order parameter describing the orientational and conformational variations of protein functional groups around the average molecular values from a single polarized spectrum. We will discuss the development of these methods and compare them to amide hydrogen/deuterium exchange methods for albumin in solution and on different polymer surfaces to show that our order parameter is related to protein stability.

  7. Lattice Simulations and Infrared Conformality

    SciTech Connect

    Appelquist, Thomas; Fleming, George T.; Lin, Meifeng; Neil, Ethan T.; Schaich, David A

    2011-09-01

    We examine several recent lattice-simulation data sets, asking whether they are consistent with infrared conformality. We observe, in particular, that for an SU(3) gauge theory with 12 Dirac fermions in the fundamental representation, recent simulation data can be described assuming infrared conformality. Lattice simulations include a fermion mass m which is then extrapolated to zero, and we note that this data can be fit by a small-m expansion, allowing a controlled extrapolation. We also note that the conformal hypothesis does not work well for two theories that are known or expected to be confining and chirally broken, and that it does work well for another theory expected to be infrared conformal.

  8. Arytenoid cartilage dislocation after reversed total shoulder replacement surgery in the beach chair position: a case report

    PubMed Central

    Sim, Yeo Hae; Choi, Jeong-Hyun

    2016-01-01

    Arytenoid cartilage dislocation is not a common complication, but its delayed diagnosis reduces the therapeutic effect of treatment. A male patient underwent reversed total shoulder replacement surgery in the beach chair position under general anesthesia. The patient experienced postoperative hoarseness, and it was revealed that he had right arytenoid dislocation. Voice restoration was accomplished with closed reduction. We discussed changes in patient position during the operation and how they may contribute to the arytenoid dislocation. Flexion and a slight rotation of the neck during the operation can lead to an increase in intracuff pressure of the endotracheal tube. It is necessary to check neck position and monitor intracuff pressure in patients undergoing operations in the beach chair position. Also, the anesthesiologist should suspect arytenoid dislocation in the case of persistent hoarseness after surgery in the beach chair position. PMID:27482316

  9. Estimation of Comfortable/Uncomfortable Feeling Based on EEG by Using NN and k-means Algorithm for Massage Chair

    NASA Astrophysics Data System (ADS)

    Teramae, Tatsuya; Kushida, Daisuke; Takemori, Fumiaki; Kitamura, Akira

    A present massage chair realizes the massage motion and force designed by a professional masseur. However, appropriate massage force to the user can not be provided by the massage chair in such a method. On the other hand, the professional masseur can realize an appropriate massage force to more than one patient, because, the masseur considers the physical condition of the patient. Our research proposed the intelligent massage system of applying masseur's procedure for the massage chair using estimated skin elasticity and DB to relate skin elasticity and massage force. However, proposed system has a problem that DB does not adjust to unknown user, because user's feeling by massage can not be estimated. Then, this paper proposed the estimation method of comfortable/uncomfortable feeling based on EEG using the neural network and k-means algorithm. The realizability of the proposed method is verified by the experimental works.

  10. Arytenoid cartilage dislocation after reversed total shoulder replacement surgery in the beach chair position: a case report.

    PubMed

    Sim, Yeo Hae; Choi, Jeong-Hyun; Kim, Mi Kyeong

    2016-08-01

    Arytenoid cartilage dislocation is not a common complication, but its delayed diagnosis reduces the therapeutic effect of treatment. A male patient underwent reversed total shoulder replacement surgery in the beach chair position under general anesthesia. The patient experienced postoperative hoarseness, and it was revealed that he had right arytenoid dislocation. Voice restoration was accomplished with closed reduction. We discussed changes in patient position during the operation and how they may contribute to the arytenoid dislocation. Flexion and a slight rotation of the neck during the operation can lead to an increase in intracuff pressure of the endotracheal tube. It is necessary to check neck position and monitor intracuff pressure in patients undergoing operations in the beach chair position. Also, the anesthesiologist should suspect arytenoid dislocation in the case of persistent hoarseness after surgery in the beach chair position. PMID:27482316

  11. CONFORMANCE IMPROVEMENT USING GELS

    SciTech Connect

    Randall S. Seright

    2004-03-01

    This technical progress report describes work performed from September 1, 2003, through February 29, 2004, for the project, ''Conformance Improvement Using Gels.'' We examined the properties of several ''partially formed'' gels that were formulated with a combination of high and low molecular weight HPAM polymers. After placement in 4-mm-wide fractures, these gels required about 25 psi/ft for brine to breach the gel (the best performance to date in fractures this wide). After this breach, stabilized residual resistance factors decreased significantly with increased flow rate. Also, residual resistance factors were up to 9 times greater for water than for oil. Nevertheless, permeability reduction factors were substantial for both water and oil flow. Gel with 2.5% chopped fiberglass effectively plugged 4-mm-wide fractures if a 0.5-mm-wide constriction was present. The ability to screen-out at a constriction appears crucial for particulate incorporation to be useful in plugging fractures. In addition to fiberglass, we examined incorporation of polypropylene fibers into gels. Once dispersed in brine or gelant, the polypropylene fibers exhibited the least gravity segregation of any particulate that we have tested to date. In fractures with widths of at least 2 mm, 24-hr-old gels (0.5% high molecular weight HPAM) with 0.5% fiber did not exhibit progressive plugging during placement and showed extrusion pressure gradients similar to those of gels without the fiber. The presence of the fiber roughly doubled the gel's resistance to first breach by brine flow. The breaching pressure gradients were not as large as for gels made with high and low molecular weight polymers (mentioned above). However, their material requirements and costs (i.e., polymer and/or particulate concentrations) were substantially lower than for those gels. A partially formed gel made with 0.5% HPAM did not enter a 0.052-mm-wide fracture when applying a pressure gradient of 65 psi/ft. This result

  12. CONFORMANCE IMPROVEMENT USING GELS

    SciTech Connect

    Randall S. Seright

    2004-09-30

    This report describes work performed during the third and final year of the project, ''Conformance Improvement Using Gels.'' Corefloods revealed throughput dependencies of permeability reduction by polymers and gels that were much more prolonged during oil flow than water flow. This behavior was explained using simple mobility ratio arguments. A model was developed that quantitatively fits the results and predicts ''clean up'' times for oil productivity when production wells are returned to service after application of a polymer or gel treatment. X-ray computed microtomography studies of gels in strongly water-wet Berea sandstone and strongly oil-wet porous polyethylene suggested that oil penetration through gel-filled pores occurs by a gel-dehydration mechanism, rather than gel-ripping or gel-displacement mechanisms. In contrast, analysis of data from the University of Kansas suggests that the gel-ripping or displacement mechanisms are more important in more permeable, strongly water-wet sandpacks. These findings help to explain why aqueous gels can reduce permeability to water more than to oil under different conditions. Since cement is the most commonly used material for water shutoff, we considered when gels are preferred over cements. Our analysis and experimental results indicated that cement cannot be expected to completely fill (top to bottom) a vertical fracture of any width, except near the wellbore. For vertical fractures with apertures less than 4 mm, the cement slurry will simply not penetrate very far into the fracture. For vertical fractures with apertures greater than 4 mm, the slurry may penetrate a substantial distance into the bottom part of the fracture. However, except near the wellbore, the upper part of the fracture will remain open due to gravity segregation. We compared various approaches to plugging fractures using gels, including (1) varying polymer content, (2) varying placement (extrusion) rate, (3) using partially formed gels, (4

  13. Protein Allostery and Conformational Dynamics.

    PubMed

    Guo, Jingjing; Zhou, Huan-Xiang

    2016-06-01

    The functions of many proteins are regulated through allostery, whereby effector binding at a distal site changes the functional activity (e.g., substrate binding affinity or catalytic efficiency) at the active site. Most allosteric studies have focused on thermodynamic properties, in particular, substrate binding affinity. Changes in substrate binding affinity by allosteric effectors have generally been thought to be mediated by conformational transitions of the proteins or, alternatively, by changes in the broadness of the free energy basin of the protein conformational state without shifting the basin minimum position. When effector binding changes the free energy landscape of a protein in conformational space, the change affects not only thermodynamic properties but also dynamic properties, including the amplitudes of motions on different time scales and rates of conformational transitions. Here we assess the roles of conformational dynamics in allosteric regulation. Two cases are highlighted where NMR spectroscopy and molecular dynamics simulation have been used as complementary approaches to identify residues possibly involved in allosteric communication. Perspectives on contentious issues, for example, the relationship between picosecond-nanosecond local and microsecond-millisecond conformational exchange dynamics, are presented. PMID:26876046

  14. CONFORMANCE IMPROVEMENT USING GELS

    SciTech Connect

    Randall S. Seright

    2003-09-01

    This report describes work performed during the second year of the project, ''Conformance Improvement Using Gels.'' The project has two objectives. The first objective is to identify gel compositions and conditions that substantially reduce flow through fractures that allow direct channeling between wells, while leaving secondary fractures open so that high fluid injection and production rates can be maintained. The second objective is to optimize treatments in fractured production wells, where the gel must reduce permeability to water much more than that to oil. Pore-level images from X-ray computed microtomography were re-examined for Berea sandstone and porous polyethylene. This analysis suggests that oil penetration through gel-filled pores occurs by a gel-dehydration mechanism, rather than a gel-ripping mechanism. This finding helps to explain why aqueous gels can reduce permeability to water more than to oil. We analyzed a Cr(III)-acetate-HPAM gel treatment in a production well in the Arbuckle formation. The availability of accurate pressure data before, during, and after the treatment was critical for the analysis. After the gel treatment, water productivity was fairly constant at about 20% of the pre-treatment value. However, oil productivity was stimulated by a factor of 18 immediately after the treatment. During the six months after the treatment, oil productivity gradually decreased to approach the pre-treatment value. To explain this behavior, we proposed that the fracture area open to oil flow was increased substantially by the gel treatment, followed by a gradual closing of the fractures during subsequent production. For a conventional Cr(III)-acetate-HPAM gel, the delay between gelant preparation and injection into a fracture impacts the placement, leakoff, and permeability reduction behavior. Formulations placed as partially formed gels showed relatively low pressure gradients during placement, and yet substantially reduced the flow capacity of

  15. To Conform or Not to Conform: Spontaneous Conformity Diminishes the Sensitivity to Monetary Outcomes

    PubMed Central

    2013-01-01

    When people have different opinions in a group, they often adjust their own attitudes and behaviors to match the group opinion, known as social conformity. The affiliation account of normative conformity states that people conform to norms in order to ‘fit in’, whereas the accuracy account of informative conformity posits that the motive to learn from others produces herding. Here, we test another possibility that following the crowd reduces the experienced negative emotion when the group decision turns out to be a bad one. Using event related potential (ERP) combined with a novel group gambling task, we found that participants were more likely to choose the option that was predominately chosen by other players in previous trials, although there was little explicit normative pressure at the decision stage and group choices were not informative. When individuals' choices were different from others, the feedback related negativity (FRN), an ERP component sensitive to losses and errors, was enhanced, suggesting that being independent is aversive. At the outcome stage, the losses minus wins FRN effect was significantly reduced following conformity choices than following independent choices. Analyses of the P300 revealed similar patterns both in the response and outcome period. Our study suggests that social conformity serves as an emotional buffer that protects individuals from experiencing strong negative emotion when the outcomes are bad. PMID:23691242

  16. Implementing a Paid Leave Policy for Graduate Students at UW-Madison: The Department Chair Perspective

    NASA Astrophysics Data System (ADS)

    Mathieu, Robert D.

    2013-01-01

    In 2010 the University of Wisconsin - Madison Astronomy Department developed and implemented a departmental paid leave policy for our graduate students, even though the university lacks a campus-wide policy and cannot provide institutional funding for such programs. This policy includes 12 weeks of paid leave in event of a medical emergency or chronic medical condition, as well as paid parental leave for both male and female graduate research assistants. Building on the graduate student perspective of Gosnell (2012), I will discuss the process of this successful development of a departmental family and medical leave policy for graduate students from the perspective of a faculty member and chair. In particular I will discuss implications of university policies, the importance of faculty and staff support, the role of private funds, and issues of effort certification.

  17. Do institutional logics predict interpretation of contract rules at the dental chair-side?

    PubMed

    Harris, Rebecca; Brown, Stephen; Holt, Robin; Perkins, Elizabeth

    2014-12-01

    In quasi-markets, contracts find purchasers influencing health care providers, although problems exist where providers use personal bias and heuristics to respond to written agreements, tending towards the moral hazard of opportunism. Previous research on quasi-market contracts typically understands opportunism as fully rational, individual responses selecting maximally efficient outcomes from a set of possibilities. We take a more emotive and collective view of contracting, exploring the influence of institutional logics in relation to the opportunistic behaviour of dentists. Following earlier qualitative work where we identified four institutional logics in English general dental practice, and six dental contract areas where there was scope for opportunism; in 2013 we surveyed 924 dentists to investigate these logics and whether they had predictive purchase over dentists' chair-side behaviour. Factor analysis involving 300 responses identified four logics entwined in (often technical) behaviour: entrepreneurial commercialism, duty to staff and patients, managerialism, public good. PMID:25441320

  18. News from the ``Dentist's Chair'': Observations of AM1353-272 with the VIMOS IFU

    NASA Astrophysics Data System (ADS)

    Weilbacher, P. M.; Duc, P.-A.

    The galaxy pair AM 1353-272 nicknamed "The Dentist's Chair" shows two ˜30 kpc long tidal tails. Previous observations using multi-slit masks showed that they host up to seven tidal dwarf galaxies. The kinematics of these tidal dwarfs appeared to be decoupled from the surrounding tidal material. New observations of the tip of the southern tidal tail with the VIMOS integral field unit confirm the results for two of these genuine tidal dwarfs but raise doubts whether the velocity gradient attributed to the outermost tidal dwarf candidate is real. We also discuss possible effects to explain the observational difference concerning the strongest velocity gradient seen in the slit data, which is undetected in the new integral field data, but arrive at no firm conclusion. Additionally, low-resolution data covering most of the two interacting partners show that the strongest line emitting regions of this system are the central parts.

  19. [The creation of chairs in tropical medicine in Peru and Brazil].

    PubMed

    Almeida, Marta de

    2011-06-01

    At the 5th Latin American Congress of Medicine, held in Lima, Peru, in 1913, the idea was put forth to establish chairs in Tropical Medicine at medical schools in Latin America. Through reference to the involvement of Julián Arce and Carlos Chagas, physicians devoted to the study of tropical medicine, the article analyzes this proposal and examines the process by which the teaching of the specialty became institutionalized in Peru and Brazil. The focus is specifically on the inaugural classes given by both professors, the former speaking before the University of San Marcos Faculty of Medicine in 1916 in Lima and the latter, before the Rio de Janeiro Faculty of Medicine in 1926. The present study hopes to contribute to a deeper understanding of the distinct meanings assigned to tropical medicine in Brazil and Peru. PMID:21779691

  20. Do institutional logics predict interpretation of contract rules at the dental chair-side?

    PubMed Central

    Harris, Rebecca; Brown, Stephen; Holt, Robin; Perkins, Elizabeth

    2014-01-01

    In quasi-markets, contracts find purchasers influencing health care providers, although problems exist where providers use personal bias and heuristics to respond to written agreements, tending towards the moral hazard of opportunism. Previous research on quasi-market contracts typically understands opportunism as fully rational, individual responses selecting maximally efficient outcomes from a set of possibilities. We take a more emotive and collective view of contracting, exploring the influence of institutional logics in relation to the opportunistic behaviour of dentists. Following earlier qualitative work where we identified four institutional logics in English general dental practice, and six dental contract areas where there was scope for opportunism; in 2013 we surveyed 924 dentists to investigate these logics and whether they had predictive purchase over dentists' chair-side behaviour. Factor analysis involving 300 responses identified four logics entwined in (often technical) behaviour: entrepreneurial commercialism, duty to staff and patients, managerialism, public good. PMID:25441320

  1. Synthesis, structural and conformational study of some esters derived from 3-methyl-3-azabicyclo[3.2.1]octan-8(α and β)-ols

    NASA Astrophysics Data System (ADS)

    Iriepa, I.; Bellanato, J.

    2014-09-01

    A series of α and β-esters bearing a 3-methyl-3-azabicyclo[3.2.1]octane moiety as well as methyl and aryl substituents were synthesized and studied by 1H and 13C NMR spectroscopies. In CDCl3 solution, at room temperature, a chair-envelope conformation for the bicycle moiety with the N-CH3 group in equatorial position with respect to the chair ring is proposed for both, α and β-esters. The chair conformation of the piperidine ring is puckered at C8 in the α-epimers and it is flattened at N3, in the β-epimers. Free rotation of the acyloxy group around the C8sbnd O bond has also been deduced. Analgesic activity of four of these substances was studied. 8β-Benzoyloxy-3-methyl-3-azabicyclo[3.2.1]octane demonstrated significant analgesic activity in the hot plate test compared to morphine. By measuring the rectal temperature in mice, results also showed a significant antipyretic activity of this compound.

  2. Chair-side preventive interventions in the Public Dental Service in Norway.

    PubMed

    Widström, E; Tillberg, A; Byrkjeflot, L I; Skudutyte-Rysstad, R

    2016-08-26

    Objective and setting In Norway, the Public Dental Service (PDS) caters for the young (<19 years) and smaller numbers of adults, mostly special needs patients. This study surveyed chair-side preventive measures used in the public clinics and compared them with recommendations in evidence-based guidelines in the neighbouring countries.Materials and methods After ethical approval, the regional Chief Dental Officers (CDOs) emailed questionnaires to their local clinics (N = 421) where the most experienced dentist and dental hygienist were asked to respond on behalf of the clinic. Answers were received from 256 clinics (response rate 61%). Altogether, 215 dentists and 166 dental hygienists answered.Results Of the respondents, 26% reported that their clinic had agreed guidelines on preventive treatment to be used by all staff. Oral hygiene and fluoride toothpaste recommendations were considered appropriate. Almost 60% claimed that flossing instructions were given to all children and adolescents and 40% that fluoride varnish was used on all the young. Fissure sealants were used after individual assessment (80%). A third of the respondents claimed that fluoride tablets and fluoride rinse were recommended for all or most children and fluoride rinses for adults, even in addition to regular use of fluoride toothpaste. Dental hygienists used all methods more often than dentists. On adults, preventive measures were more often used on individual assessment. Half (48%) of the respondents were interested in new evidence-based national guidelines on preventive care.Conclusions Chair-side preventive treatment measures were numerous in the well-resourced Norwegian PDS, but partly outdated. PMID:27561578

  3. Chair Side Application of NovaMin for the Treatment of Dentinal Hypersensitivity- A Novel Technique

    PubMed Central

    P, Padmavati; Sanghani, Nehal N

    2014-01-01

    Objective: To evaluate the efficacy of calcium sodium phosphosilicate bioactive glass (NovaMin) as a chair side desensitizing agent. Materials and Methods: The study was conducted on 60 subjects divided into 3 groups of 20 each as follows. Group I (NovaMin application without scaling and root planing), Group II (NovaMin application after scaling and root planing) and Group III (control group). Sensitivity was assessed using air blast and cold water stimulus at baseline, immediately after application, after half an hour and after 8d using Visual Analog Scale (VAS). Results: Mean VAS (air blast stimulus) for group I was 5.9 at baseline, 3.4 immediately after application, 3.05 after half an hour, and 3.0 after 8 days. In group II VAS score were 6.2, 3.35, 2.9, 2.75 and group III 6.6, 7.0, 7.0, 7.0 respectively. For cold water stimulus in group I VAS score were 5.6, 3.35, 3.15, 3.1, group II VAS score 5.7, 3.35, 3.1, 2.85 and group III 5.8, 6.1, 6.05, 6.05 respectively. VAS scores in between group I and group III and group II and group III were statistically significant (<0.001) immediately after application, after half an hour and after 8days (ANOVA). Conclusion: Chair side application of calcium phosphosilicate bioactive glass can be a therapeutic adjunct to provide immediate relief for the patient with dentinal hypersensitivity. PMID:25478437

  4. Monte Carlo simulation of shielded chair whole body counting system with Masonite cut sheet phantom

    NASA Astrophysics Data System (ADS)

    Manohari, M.; Mathiyarasu, R.; Rajagopal, V.; Venkatraman, B.

    2015-05-01

    The shielded chair wholebody counting system used at IGCAR is calibrated experimentally using Masonite cut sheet phantom loaded with single radionuclide of known activity. Multiple point sources of a particular radionuclide are distributed at mid-thickness in each segment of the phantom during calibration. Though the detector can be used for the measurement of gamma photons upto 3000 keV, the experimental calibration is done only upto 1500 keV according to the requirement of measurement of fission and activation products, which emits gamma energies predominantly in the regions below 1500 keV. The expertize in numerical Monte Carlo simulation was utilized to obtain the efficiency values above 1500 keV. This paper focuses on the validation of the shielded chair counting system model using the Masonite cut sheet phantom measurements and applying the validated model to extend the energy range of the calibration upto 3 MeV. A good agreement of the theoretically simulated and experimental 137Cs spectrum with respect to the spectral shape, counts in all the energy regions and the photopeak efficiency validated the modeling of the counting system. A mathematical function to fit the counting efficiencies with photon energies was developed and a set of fitting parameters were established so that the efficiency value of any energy upto 3 MeV can be obtained without performing experimental efficiency calibration. The efficiency values obtained from the fit were compared with experimental ones and found to be in agreement, i.e., within 8% for the 250-1500 keV energy range. The Compton scattering factors (CSFs) at different low energies due to high energy photons were also simulated. The theoretical and experimental CSFs were compared and found to be matching within ±20%. Simulations with uniform source distribution inside the Masonite phantom has shown that the current source distribution followed at IGCAR gives efficiency values within ±5% compared to that of uniform

  5. Theoretical approach to the conformational analyses of dithiazinane, thiadiazinane and triazinane, their N-borane adducts and N-H cations

    NASA Astrophysics Data System (ADS)

    Suárez-Moreno, Galdina V.; Xotlanihua-Flores, Alfonso; Vela, Alberto; Contreras, Rosalinda; Flores-Parra, Angelina

    2016-06-01

    Computational methods were applied to the study of the different nitrogen and chair conformers of [1,3,5]-dithiazinanes, [1,3,5]-thiadiazinanes and [1,3,5]-triazinanes. Optimisation of heterocycles bearing N-H and N-Me were performed by B3LYP density functional and the 6-311++G** basis set methods, and their free energies were correlated. N-Borane adducts and the protonated cations of these heterocycles were also optimized. The relative free energy differences (ΔG) in gas phase of the chair conformers of eighteen heterocycles were calculated. Calculations agree with experimental data and allow to explain the steric and electronic factors that determine the preferred conformations. The distribution of the electronic density and the NBO atomic charges of the optimized structures support the experimental conformational analyses. The bonding and intramolecular interactions were analysed by using critical point search of the electronic density. They were also evaluated by exchange reduced density gradients associated to overlapping, using the PBE functional with the DZUP basis set. Proton-hydride, proton-proton, hydride-hydride, hydride-sulphur, proton-sulphur and hydride-nitrogen stabilising weak interactions were analysed.

  6. DOE Chair of Excellence in Environmental Disciplines-Final Technical Report

    SciTech Connect

    Kurunganty, Sastry; Loran, Roberto; Roque-Malherbe, Rolando; Hijazi, Yazan; Nieto, Santander; Gomez, Will A.; Duconge, Jose; Cotto, María del C.; Muniz, Carlos; Diaz, Francisco J.; Neira, Carlos F.; Marquez, Francisco; Del Valle, W.; Thommes, M.

    2014-02-19

    The report Massie Chair of Excellence Program at Universidad del Turabo, contract DE-FG02-95EW12610, during the period of 9/29/1995 to 9/29/2011. The initial program aims included development of academic programs in the Environmental Sciences and Engineering, and Research and Development focused initially on environmentally friendly processes and later revised also include: renewable energy and international cooperation. From 1995 -2005, the Program at UT lead the establishment of the new undergraduate program in electrical engineering at the School of Engineering (SoE), worked on requirements to achieve ABET accreditation of the SoE B.S. Mechanical Engineering and B.S. Electrical Engineering programs, mentored junior faculty, taught undergraduate courses in electrical engineering, and revised the electrical engineering curriculum. Engineering undergraduate laboratories were designed and developed. The following research sub-project was developed: Research and development of new perovskite-alumina hydrogen permeable asymmetrical nanostructured membranes for hydrogen purification, and extremely high specific surface area silica materials for hydrogen storage in the form of ammonia, Dr. Rolando Roque-Malherbe Subproject PI, Dr. Santander Nieto and Mr. Will Gómez Research Assistants. In 2006, the Massie Chair of Excellence Program was transferred to the National Nuclear Security Agency, NNSA and DNN. DoE required a revised proposal aligned with the priorities of the Administration. The revised approved program aims included: (1) Research (2) Student Development: promote the development of minority undergraduate and graduate students through research teams, internships, conferences, new courses; and, (3) Support: (a) Research administration and (b) Dissemination through international conferences, the UT Distinguished Lecturer Series in STEM fields and at the annual Universidad del Turabo (UT) Researchers Conference. Research included: Sub-Project 1: Synthesis and

  7. The principle of conformational signaling.

    PubMed

    Tompa, Peter

    2016-07-25

    Signal transduction is the primary process by which cells respond to changes in their physical and chemical environments. Cellular response is initiated through a signaling protein (a receptor), which interacts with the "signal", most often a novel molecule outside or inside the cell. The mechanism of activation of the receptor is a conformational change and/or covalent modification, which then sets in motion a signaling pathway, i.e. a cascade of modification and binding events that relay and amplify the message to eventually alter the state of the cell. In reflection of this general perception, concepts such as the "second messenger" and the "phosphorylation cascade" dominate our views of signal transduction. The idea I advocate here is that the non-covalent change in protein conformation itself might serve as the initial or intermittent "signal" in the cascade, and it is often the primary event being recognized and interpreted by downstream receptor(s). This signaling principle is intertwined with many other cellular regulatory concepts, such as (pathway) allostery, conformational spread, induced folding/unfolding, conformational memory, the hierarchical assembly of complexes, and the action of regulatory chaperones and prions. By elaborating on many examples and also recent advances in experimental methodology, I show that conformational signaling, although thus far underappreciated, is a general and robust signaling principle that most of the time operates in close interplay with covalent signals in the cell. PMID:27242242

  8. Bis(toluene)chromium(I) [1,2,5]thiadiazolo[3,4-c][1,2,5]thiadiazolidyl and [1,2,5]thiadiazolo[3,4-b]pyrazinidyl: new heterospin (S1 = S2 = ½) radical-ion salts.

    PubMed

    Semenov, Nikolay A; Pushkarevsky, Nikolay A; Suturina, Elizaveta A; Chulanova, Elena A; Kuratieva, Natalia V; Bogomyakov, Artem S; Irtegova, Irina G; Vasilieva, Nadezhda V; Konstantinova, Lidia S; Gritsan, Nina P; Rakitin, Oleg A; Ovcharenko, Victor I; Konchenko, Sergey N; Zibarev, Andrey V

    2013-06-01

    Bis(toluene)chromium(0), Cr(0)(η(6)-C7H8)2 (3), readily reduced [1,2,5]thiadiazolo[3,4-c][1,2,5]thiadiazole (1) and [1,2,5]thiadiazolo[3,4-b]pyrazine (2) in a tetrahydrofuran solvent with the formation of heterospin, S1 = S2 = ½, radical-ion salts [3](+)[1](-) (4) and [3](+)[2](-) (5) isolated in high yields. The salts 4 and 5 were characterized by single-crystal X-ray diffraction (XRD), solution and solid-state electron paramagnetic resonance, and magnetic susceptibility measurements in the temperature range 2-300 K. Despite the formal similarity of the salts, their crystal structures were very different and, in contrast to 4, in 5 anions were disordered. For the XRD structures of the salts, parameters of the Heisenberg spin Hamiltonian were calculated using the CASSCF/NEVPT2 and broken-symmetry density functional theory approaches, and the complex magnetic motifs featuring the dominance of antiferromagnetic (AF) interactions were revealed. The experimental χT temperature dependences of the salts were simulated using the Van Vleck formula and a diagonalization of the matrix of the Heisenberg spin Hamiltonian for the clusters of 12 paramagnetic species with periodic boundary conditions. According to the calculations and χT temperature dependence simulation, a simplified magnetic model can be suggested for the salt 4 with AF interactions between the anions ([1](-)···[1](-), J1 = -5.77 cm(-1)) and anions and cations ([1](-)···[3](+), J2 = -0.84 cm(-1)). The magnetic structure of the salt 5 is much more complex and can be characterized by AF interactions between the anions, [2](-)···[2](-), and by both AF and ferromagnetic (FM) interactions between the anions and cations, [2](-)···[3](+). The contribution from FM interactions to the magnetic properties of the salt 5 is in qualitative agreement with the positive value of the Weiss constant Θ (0.4 K), whereas for salt 4, the constant is negative (-7.1 K). PMID:23687983

  9. Walking the Tightrope: The Balance between Innovation and Leadership. Proceedings of the Annual International Conference of the Chair Academy (6th, Reno, NV, February 12-15, 1997).

    ERIC Educational Resources Information Center

    National Community Coll. Chair Academy, Mesa, AZ.

    The papers provided in this proceedings discuss the roles and responsibilities of chairs, deans, and other organizational leaders at community colleges, focusing on strategies for balancing innovative educational approaches with traditional leadership. Following background material on the Chair Academy, the following three keynote speeches are…

  10. Strengthening Departmental Leadership: A Team-Building Guide for Chairs in Colleges and Universities. The Jossey-Bass Higher and Adult Education Series.

    ERIC Educational Resources Information Center

    Lucas, Ann F.

    This book demonstrates how academic chairs at institutions of higher education can learn the skills that are essential to their becoming leaders and faculty developers and having a significant impact on their departments. The book assists chairs in building cohesive teams in their departments and facilitates learning and using survival skills. It…

  11. Comparison of center-of-pressure displacement during sit-to-stand according to chair height in children with cerebral palsy

    PubMed Central

    Lee, Hye-Young; Lee, In-Hee

    2015-01-01

    [Purpose] In patients with cerebral palsy (CP), performance of the sit-to-stand (STS) task is influenced by an asymmetrical motor pattern. The purpose of this study was to analyze the effects of an elevated chair on STS performance in patients with CP. [Subjects and Methods] Nine CP patients performed STS from a height-adjustable instrumented chair at their natural speed, with the ankle at a 90° angle to the floor. The center-of-pressure (COP) displacement was recorded under the feet. Each foot position was tested at two chair heights corresponding to 100% and 120% of the leg length. The extent and speed of COP were calculated. [Results] The anteroposterior speed and extent of COP were greater with the standard chair than with the elevated chair. The other parameters such as mediolateral speed, extent, and vertical speed of the COP were not different between the two chairs. [Conclusion] These findings suggest that the sway with STS performed from the elevated chair was lesser than that with STS performed from the standard chair. This information will be relevant to clinicians involved in the rehabilitation of CP patients and will help identify factors that influence STS performance. PMID:26311970

  12. Female Academic Department Chairs at a Public, Very High Research Activity University: Exploring Their Career Pathways to Success

    ERIC Educational Resources Information Center

    St. Marthe, Tamara Jaslene Marcelle

    2012-01-01

    The advancement of women into academic leadership remains a problem facing public, high-research activity universities. While there are more women who are qualified to assume the position of department chair in research institutions today than there were 30 years ago, women still lag behind their male counterparts in holding these academic…

  13. The perception of science department chairs regarding the performance of community college science majors transferring to 4-year institutions

    NASA Astrophysics Data System (ADS)

    Ford, Brenda Jordan

    The purpose for conducting the study was to determine the perceptions held by science department chairs toward 2-year college transfer students regarding their ability to succeed in upper level science courses as compared to that of native students. A two-section, researcher-developed questionnaire was utilized to collect data. The first section was related to demographic information about the department chair's institution, such as institution size, number of transfer students at the institution, and the post-graduate plans of students. The second section presented 15 skills that if found in students should lead to academic success. A total of 61 (N = 61) surveys were returned, representing an overall return rate of 54.4%. The mean, the standard deviation, and paired t-tests were used to analyze the data. Results showed that science department chairs perceived significant differences in native and transfer students. The significant differences found between native and transfer students became greater as the size of the institution increased. The significant differences found between native and transfer students became less the greater the number of transfer students attending an institution. Significant differences were found between students planning to attend professional school and students going to jobs after graduation. No significant differences were found between students going to graduate school and those who were undecided about post-graduation plans. Two-year college transfer students were perceived by department chairs as having the ability to be academically successful at 4-year institutions.

  14. Is the Process the Problem? Impact of Selection Methods on Reported Job Satisfaction among Academic Department Chairs

    ERIC Educational Resources Information Center

    Fairchild, Julie E.

    2013-01-01

    The problem of low job satisfaction (JS) among academic department chairs (ADC) may result from the selection process. ADC searches seldom comply with best practices for hiring or are predictive of a good fit. Formal searches are seldom used. Some incumbents did not want the job. Research into the history, nature, and problems of the position…

  15. 77 FR 39680 - Folding Metal Tables and Chairs From the People's Republic of China: Final Results of Antidumping...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... FR 13539 (March 7, 2012) (``Preliminary Results''). DATES: Effective Date: July 5, 2012. FOR FURTHER... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of China: Final... Preliminary Results of administrative review of the antidumping duty order on folding metal tables and...

  16. 76 FR 774 - Folding Metal Tables and Chairs From the People's Republic of China: Notice of Extension of Time...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... New Shipper Review, 75 FR 44767 (July 29, 2010). This review covers the period June 1, 2009, through... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of China: Notice...'') published the initiation of the new shipper review of the antidumping duty order on folding metal tables...

  17. Pushing for the "Sputnik Moment": A Conversation with Arizona Governor and National Governor's Association Chair, Janet Napolitano

    ERIC Educational Resources Information Center

    McLester, Susan

    2007-01-01

    Janet Napolitano is the governor of Arizona and chair of the National Governor's Association. Napolitano, a Democrat, has brought a new energy to her state and to the nation with initiatives that demonstrate the fact that she really means business. Topping the list is Innovation America, which aims to drive American competitiveness via government…

  18. Leading Academic Change: Essential Roles for Department Chairs. The Jossey-Bass Higher and Adult Education Series.

    ERIC Educational Resources Information Center

    Lucas, Ann F.

    This book offers a strategy for institutional change and an examination of the role of leadership in organizations. Essays focus on the shift away from faculty to a concentration on learning, especially on changes in the role of the department chair. The 12 essays are organized in three parts: Part 1, "Leading Change," includes: "A Teamwork…

  19. 75 FR 57827 - Notice of Meeting of the Committee of Chairs of the Industry Trade Advisory Committees (ITACs)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... Agenda for the closed portion of the meeting will be the Trade Policy Agenda, including discussion of... TRADE REPRESENTATIVE Notice of Meeting of the Committee of Chairs of the Industry Trade Advisory Committees (ITACs) AGENCY: Office of the United States Trade Representative. ACTION: Notice of a...

  20. 77 FR 71168 - Folding Metal Tables and Chairs From the People's Republic of China: Final Results of Sunset...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-29

    ... China, 67 FR 43277 (June 27, 2002). \\2\\ See Folding Metal Tables and Chairs From the People's Republic of China: Continuation of the Antidumping Duty Order, 72 FR 62626 (November 6, 2007). \\3\\ See Initiation of Five-Year (``Sunset'') Review, 77 FR 59897 (October 1, 2012). We did not receive a notice...

  1. Hitchcock versus Shaker Chairs: Artifacts to Teach about the Rise and Rejection of Industrialism in the Young Republic

    ERIC Educational Resources Information Center

    Morris, Ronald Vaughan

    2008-01-01

    Students in elementary gifted class use discovery to learn about life in industrial New England. Taking multiple days to analyze this topic, students use artifacts (chairs), discussion, and primary sources to explore the politics of the 1830s. They examine the workings of Hitchcockville, Connecticut, and a Massachusetts Shaker colony. Students…

  2. Physics for the 1990s. AAPT Conference of Department Chairs in Physics. (February 19-20, 1988).

    ERIC Educational Resources Information Center

    McDermott, Mark N., Ed.; Wilson, Jack M., Ed.

    This book contains the proceedings of the Third Topical Conference of Department Chairs in Physics. Topics of the papers summarized include: (1) research centers sponsored by the National Science Foundation; (2) physics programs at the undergraduate and graduate levels; (3) the use of accelerators in education and research; (4) approaches to…

  3. The Chair/Dean as Entrepreneurial Leader: How To Increase Support and Funding for Your Department or Area.

    ERIC Educational Resources Information Center

    Barnes, Terry

    As costs for higher education increase and traditional state appropriations formulae, in which dollars follow student/semester credit hours, are often no longer in use, educational institutions are being asked to provide higher quality services with flat or even slightly reduced budgets. To meet these needs, department chairs and deans need to…

  4. 75 FR 69400 - Folding Metal Tables and Chairs From the People's Republic of China: Extension of Time Limit for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... Duty Administrative Reviews and Deferral of Administrative Review, 74 FR 37690 (July 29, 2009). On July..., 75 FR 40788 (July 14, 2010). The 2008-2009 administrative review covers the period June 1, 2008... International Trade Administration Folding Metal Tables and Chairs From the People's Republic of...

  5. 76 FR 12024 - Folding Metal Tables and Chairs From the People's Republic of China: Notice of Extension of Time...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-04

    ... Reviews and Requests for Revocations in Part, 75 FR 44224 (July 28, 2010) and Folding Metal Tables and Chairs from the People's Republic of China: Initiation of New Shipper Review, 75 FR 44767 (July 29, 2010... Administrative and New Shipper Reviews AGENCY: Import Administration, International Trade...

  6. 75 FR 56651 - Notice of Cancellation of Meeting of the Chairs of the Industry Trade Advisory Committee (ITACs)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... From the Federal Register Online via the Government Publishing Office OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE Notice of Cancellation of Meeting of the Chairs of the Industry Trade Advisory Committee (ITACs) AGENCY: Office of the United States Trade Representative. ACTION: Notice......

  7. Local Board Chair Perspectives on Reform in North Carolina: State Decentralization as a Challenge for District Leadership.

    ERIC Educational Resources Information Center

    Keedy, John L.; Freeman, Eric

    2002-01-01

    Interviews 16 school board chairs in North Carolina to determine their attitudes toward state education reform legislation. Discusses two themes emerging from the interviews: Downsizing the state bureaucracy translates into autonomy and accountability at the local level, but paradoxically boards now lack the organizational buffering previously…

  8. Nonlocal gravity: Conformally flat spacetimes

    NASA Astrophysics Data System (ADS)

    Bini, Donato; Mashhoon, Bahram

    2016-04-01

    The field equations of the recent nonlocal generalization of Einstein’s theory of gravitation are presented in a form that is reminiscent of general relativity. The implications of the nonlocal field equations are studied in the case of conformally flat spacetimes. Even in this simple case, the field equations are intractable. Therefore, to gain insight into the nature of these equations, we investigate the structure of nonlocal gravity (NLG) in 2D spacetimes. While any smooth 2D spacetime is conformally flat and satisfies Einstein’s field equations, only a subset containing either a Killing vector or a homothetic Killing vector can satisfy the field equations of NLG.

  9. Conformational dynamics through an intermediate

    NASA Astrophysics Data System (ADS)

    Garai, Ashok; Zhang, Yaojun; Dudko, Olga K.

    2014-04-01

    The self-assembly of biological and synthetic nanostructures commonly proceeds via intermediate states. In living systems in particular, the intermediates have the capacity to tilt the balance between functional and potentially fatal behavior. This work develops a statistical mechanical treatment of conformational dynamics through an intermediate under a variable force. An analytical solution is derived for the key experimentally measurable quantity—the distribution of forces at which a conformational transition occurs. The solution reveals rich kinetics over a broad range of parameters and enables one to locate the intermediate and extract the activation barriers and rate constants.

  10. Molecular mechanics conformational analysis of tylosin

    NASA Astrophysics Data System (ADS)

    Ivanov, Petko M.

    1998-01-01

    The conformations of the 16-membered macrolide antibiotic tylosin were studied with molecular mechanics (AMBER∗ force field) including modelling of the effect of the solvent on the conformational preferences (GB/SA). A Monte Carlo conformational search procedure was used for finding the most probable low-energy conformations. The present study provides complementary data to recently reported analysis of the conformations of tylosin based on NMR techniques. A search for the low-energy conformations of protynolide, a 16-membered lactone containing the same aglycone as tylosin, was also carried out, and the results were compared with the observed conformation in the crystal as well as with the most probable conformations of the macrocyclic ring of tylosin. The dependence of the results on force field was also studied by utilizing the MM3 force field. Some particular conformations were computed with the semiempirical molecular orbital methods AM1 and PM3.

  11. Defects in conformal field theory

    NASA Astrophysics Data System (ADS)

    Billò, Marco; Gonçalves, Vasco; Lauria, Edoardo; Meineri, Marco

    2016-04-01

    We discuss consequences of the breaking of conformal symmetry by a flat or spherical extended operator. We adapt the embedding formalism to the study of correlation functions of symmetric traceless tensors in the presence of the defect. Two-point functions of a bulk and a defect primary are fixed by conformal invariance up to a set of OPE coefficients, and we identify the allowed tensor structures. A correlator of two bulk primaries depends on two cross-ratios, and we study its conformal block decomposition in the case of external scalars. The Casimir equation in the defect channel reduces to a hypergeometric equation, while the bulk channel blocks are recursively determined in the light-cone limit. In the special case of a defect of codimension two, we map the Casimir equation in the bulk channel to the one of a four-point function without defect. Finally, we analyze the contact terms of the stress-tensor with the extended operator, and we deduce constraints on the CFT data. In two dimensions, we relate the displacement operator, which appears among the contact terms, to the reflection coefficient of a conformal interface, and we find unitarity bounds for the latter.

  12. Precision conformal optics technology program

    NASA Astrophysics Data System (ADS)

    Trotta, Patrick A.

    2001-09-01

    Conformal optics are defined as optics that deviate from conventional form to best satisfy the contour and shape needs of system platforms. Precision Conformal Optics Technology (PCOT), a comprehensive 48 month program funded by the Defense Advanced Research Program Agency (DARPA) and the U. S. Army Missile Research, Development, and Engineering Center (MRDEC), assessed the potential benefits achieved by use of conformal optics on a variety of U.S. weapon systems. Also addressed were all barriers impeding conformal optics use. The PCOT program was executed by a consortium of organizations ranging from major U.S. defense prime contractors, to small businesses, and academia. The diversity of organizations encouraged synergy across a broad array of skills and perspectives. Smooth team interaction was made possible by the 845 contractual structure of the program. Benefits identified by the PCOT consortium included major reductions in aerodynamic drag (by as much as 50%), reduced time-to-targets (by as much as 60%), and reduced weapon signatures. Impediments addressed included inadequacies in optical design tools, optical manufacturing methods and equipment, optical testing, and system integration. The PCOT program was successfully completed with a demonstration of a highly contoured missile dome, which reduced overall missile drag by 25%, and led to a predicted twofold increase in missile range.

  13. Temperature: Human Regulating, Ants Conforming

    ERIC Educational Resources Information Center

    Clopton, Joe R.

    2007-01-01

    Biological processes speed up as temperature rises. Procedures for demonstrating this with ants traveling on trails, and data gathered by students on the Argentine ant ("Linepithema humile") are presented. The concepts of temperature regulation and conformity are detailed with a focus on the processes rather than on terms that label the organisms.

  14. Parsimony in Protein Conformational Change

    PubMed Central

    Chapman, Brynmor K.; Davulcu, Omar; Skalicky, Jack J.; Brüschweiler, Rafael P.; Chapman, Michael S.

    2015-01-01

    Summary Protein conformational change is analyzed by finding the minimalist backbone torsion angle rotations that superpose crystal structures within experimental error. Of several approaches to enforcing parsimony during flexible least-squares superposition, an ℓ1-norm restraint provided greatest consistency with independent indications of flexibility from NMR relaxation dispersion and chemical shift perturbation in arginine kinase, and four previously studied systems. Crystallographic cross-validation shows that the dihedral parameterization describes conformational change more accurately than rigid-group approaches. The rotations that superpose the principal elements of structure constitute a small fraction of the raw (φ, ψ)-differences that also reflect local conformation and experimental error. Substantial long-range displacements can be mediated by modest dihedral rotations, accommodated even within α-helices and β-sheets without disruption of hydrogen bonding at the hinges. Consistency between ligand-associated and intrinsic motions (in the unliganded state) implies that induced changes tend to follow low-barrier paths between conformational sub-states that are in intrinsic dynamic equilibrium. PMID:26095029

  15. Correct Representation of Conformational Equilibria.

    ERIC Educational Resources Information Center

    Fulop, F.; And Others

    1983-01-01

    In representing conformational equilibria of compounds having only one chiral center, erroneous formulas showing different antipodes on the two sides of the equilibrium are rare. In contrast, with compounds having two or more chiral centers especially with saturated heterocycles, this erroneous representation occurs frequently in the chemical…

  16. Psychological Androgyny and Social Conformity.

    ERIC Educational Resources Information Center

    Brehony, Kathleen; And Others

    The decisions and attitudes of sex-stereotyped and androgynous individuals (as defined by the Bem Sex Role Inventory) were compared in a social conformity paradigm. On each of 160 trials subjects predicted one of two possible stimuli after hearing predictions of two other "subjects." No effects of physical sex were observed. On trials when the…

  17. Astronomy from the chair - the application of the Internet in promoting of Astronomy

    NASA Astrophysics Data System (ADS)

    Tomic, Zoran

    2014-05-01

    Internet and modern communication technologies are an indispensable part of modern life. The use of the Internet makes it possible to enhance the education and expand opportunities for acquiring new knowledge. One example is Astronomy, where today thanks to the Internet, we can control telescopes that are distant from us and listen to lectures from Universities in other countries. "Astronomy from the chair" is the name for a concept where amateur astronomers can deal with astronomy from their homes using the Internet. The concept can be divided into four sections depending on the content being offered: Robotic Observatory, Virtual Observatory, Online astronomy broadcasting and Online courses. Robotic observatory is defined as an astronomical instrument and detection system that enables efficient observation without the need of a person's physical intervention. Virtual Observatory is defined as a collection of databases and software tools that use the Internet as a platform for scientific research. Online astronomy broadcasting is part of concept "Astronomy from the chair" which gives users the opportunity to get directly involved in astronomical observation organized by an amateur astronomer from somewhere in the world. Online courses are groups of sites and organizations that provide the opportunity to amateur astronomers to attend lectures, save and watch video materials from lectures, do homework, communicate with other seminar participants and in that way become familiar with the various areas of Astronomy. This paper discusses a new concept that describes how the Internet can be applied in modern education. In this paper will be described projects that allows a large number of astronomy lovers to do their own research without the need to own a large and expensive set of astronomical equipment (Virtual Telescope from Italy, Observatory "Night Hawk" from Serbia and project "Astronomy from an armchair" at Faculty of Sciences and Mathematics in Nis), to help

  18. The work covenant: a management strategy for department chairs and program directors.

    PubMed

    Durham, Timothy M; Lange, Brian

    2004-01-01

    Learning contracts have been used in adult education to ensure a positive and successful learning process. By means of a learning contract, the instructor can support the learner in a manner that best suits the learner's individual requirements. Like the learning environment, the workplace finds individuals with varying skill sets, areas of interest, and degrees of motivation. Understanding and applying the skills of the worker to appropriate tasks and interests have important ramifications for how workers perceive their jobs and the ultimate effectiveness of the organization. Studies show that the quality of the work environment is critical for the job satisfaction and retention of employees in the public and private sector as well as for the dental academician. Recent literature on faculty development has focused on adapting business-based motivation, mentoring, and performance counseling strategies to the academic setting. By leading and managing faculty development through the use of such strategies, the quality of the work environment can be improved. This article briefly summarizes the commonality between retention strategies and learning contracts within a human resource context and provides a model document that can be used by chairs and program directors to organize and focus their faculty development efforts. PMID:14761174

  19. Paracrine, endocrine and neurocrine controls of the adipocyte color phenotype: view from the chair

    PubMed Central

    Picard, F

    2015-01-01

    After a long drought caused by misjudged irrelevance to human biology, the research field of brown adipose tissue has seen a period of resurgence since 2009 when discoveries of brown fat in adults were reported. However, the molecular and physiological regulators of the different types of adipose tissues—white, beige or brown—are still far from being fully determined. Speakers of the morning session of the 16th Annual Symposium of the Université Laval's Chair in Obesity, a series interestingly launched in 1998 precisely on the topic of uncoupling proteins, presented past and recent findings on non-adrenergic signaling pathways—both upstream and downstream—regulating the metabolic and thermogenic activities of adipose tissue. They went on to show that these pathways are altered in the contexts of obesity and aging, the latter being a very important factor involved in the decline of non-shivering thermogenesis. Whereas opinions diverged on readily applicable solutions for development of candidate therapeutics, the panelists agreed that the new factors involved in the control of the adipose thermogenic program hold great promise for innovation. This will likely depend on how this novel knowledge is integrated into the complex regulation of thermogenesis, which will be achieved through better-defined experimental protocols, both in humans and non-human models. PMID:27152174

  20. Analysis of Sabine and Eyring equations and their application to concert hall audience and chair absorption.

    PubMed

    Beranek, Leo L

    2006-09-01

    Historically, two equations have been used for predicting reverberation times, Sabine and Eyring. A precise means is presented for determining Eyring absorption coefficients alpha(eyring) when the Sabine coefficients alpha(sabine) are known, and vice versa. Thus, either formula can be used provided the absorption coefficients for the Sabine formula are allowed to exceed 1.0. The Sabine formula is not an approximation to the Eyring equation and is not a shortcoming. Given low reverberation times, the ratio of alpha(sabine) to alpha(eyring) may become greater than 2.0. It is vital that, for correct prediction of reverberation times, the absorption coefficients used in either formula must have been determined in spaces similar in size and shape, with similar locations of high absorption (audience) areas, and with similar reverberation times. For concert halls, it is found that, when the audience area (fully occupied) and midfrequency reverberation time are postulated, the hall volume is directly proportional to the audience absorption coefficient. Approximately 6% greater room volumes are needed when choosing nonrectangular versus classical-rectangular shaped halls and approximately 10% greater volumes when choosing heavily upholstered versus medium upholstered chairs. Determinations of audience sound absorption coefficients are presented, based on published acoustical and architectural data for 20 halls. PMID:17004464

  1. Faculty Hiring and Development at BYU: Perspectives of a Recent Hire and Department Chair

    NASA Astrophysics Data System (ADS)

    Turley, R. Steven

    2002-04-01

    I will present a personal perspective on the transition from an industrial to an academic physicist. For those planning on a similar transition, I will mention several things that were helpful in preparing myself, marketing myself, and adapting to an academic setting. For instance, a significant difference between academic and industrial physics is the responsibility of classroom teaching. Several things that proved particularly useful in improving my own teaching were mentoring teaching partnerships, student evaluations, help in the tenure and promotion process, and programs available from our Faculty Center. From my current perspective as a department chair, I will further discuss mentoring practices I have found helpful with other new faculty. These include such things as inviting mentors to participate with new faculty in development workshops and providing financial and other recognition for participation as a mentor. In addition to developing professional skills, I have found that good mentoring is particularly critical in encouraging new faculty to adapt to departmental culture. Finally, I will discuss ideas I have found helpful in successfully recruiting new faculty. This involves researching, identifying, and actively recruiting faculty we think will build our department. For us, it has not been sufficient to passively rely on responses from applicants to advertisements and word-of-mouth inquiries. Through careful hiring and effective mentoring, we have developed an excellent record of having our faculty being successful in the tenure process.

  2. [Digital smile design and anterior monolithic restorations chair side fabrication with Cerec Cad/Cam system].

    PubMed

    Perez-Davidi, M

    2015-10-01

    Digital dentistry and digital smile design are both components of modern dentistry. The combination of the two enables the dentist to simulate the desired outcome, share the mock up with the patient and coordinate his or her expectations with the probable esthetic outcome. In this article a case is presented of anterior restorations performed to improve the smile and esthetics of the patient, combining the digital smile design (by Christian Coachman) and the Avatar Digital smile aide of the Cerec SW4 (sirona Germany) software for designing and the MCxI inlab milling unit for the fabrication. The patients picture was imported into the software and the model of the teeth was super imposed into the 3d picture of the face enabling positioning the incisal edge and midline in the desired place and sharing the virtual demo with the patient. All this procedure was performed after the patient had a mockup session in the mouth done according to the wax up procedure. The mockup can be scanned in the mouth and added as a protocol to the patient's digital models, to be used later in the biogeneric copy option. Using this option the software uses the outline of the mockup as guide lins for the final restoration computerized proposal. It is still an aide tool to be improved and simplified but definitely it is the present and future of chair side prosthodontics. PMID:26727845

  3. Paracrine, endocrine and neurocrine controls of the adipocyte color phenotype: view from the chair.

    PubMed

    Picard, F

    2015-08-01

    After a long drought caused by misjudged irrelevance to human biology, the research field of brown adipose tissue has seen a period of resurgence since 2009 when discoveries of brown fat in adults were reported. However, the molecular and physiological regulators of the different types of adipose tissues-white, beige or brown-are still far from being fully determined. Speakers of the morning session of the 16th Annual Symposium of the Université Laval's Chair in Obesity, a series interestingly launched in 1998 precisely on the topic of uncoupling proteins, presented past and recent findings on non-adrenergic signaling pathways-both upstream and downstream-regulating the metabolic and thermogenic activities of adipose tissue. They went on to show that these pathways are altered in the contexts of obesity and aging, the latter being a very important factor involved in the decline of non-shivering thermogenesis. Whereas opinions diverged on readily applicable solutions for development of candidate therapeutics, the panelists agreed that the new factors involved in the control of the adipose thermogenic program hold great promise for innovation. This will likely depend on how this novel knowledge is integrated into the complex regulation of thermogenesis, which will be achieved through better-defined experimental protocols, both in humans and non-human models. PMID:27152174

  4. Conformal Gravity rotation curves with a conformal Higgs halo

    NASA Astrophysics Data System (ADS)

    Horne, Keith

    2016-06-01

    We discuss the effect of a conformally coupled Higgs field on conformal gravity (CG) predictions for the rotation curves of galaxies. The Mannheim-Kazanas (MK) metric is a valid vacuum solution of CG's fourth-order Poisson equation if and only if the Higgs field has a particular radial profile, S(r) = S0 a/(r + a), decreasing from S0 at r = 0 with radial scalelength a. Since particle rest masses scale with S(r)/S0, their world lines do not follow time-like geodesics of the MK metric gμν, as previously assumed, but rather those of the Higgs-frame MK metric tilde{g}_{μ ν }=Ω ^2 g_{μ ν }, with the conformal factor Ω(r) = S(r)/S0. We show that the required stretching of the MK metric exactly cancels the linear potential that has been invoked to fit galaxy rotation curves without dark matter. We also formulate, for spherical structures with a Higgs halo S(r), the CG equations that must be solved for viable astrophysical tests of CG using galaxy and cluster dynamics and lensing.

  5. Conformational flexibility in 2,2'-Dioxybiphenyl-chloro-cyclotetraphosphazenes and its relevance to polyphosphazene analogues.

    PubMed

    Ainscough, Eric W; Brodie, Andrew M; Chaplin, Adrian B; Derwahl, Andreas; Harrison, John A; Otter, Carl A

    2007-04-01

    The reaction of the cyclotetraphosphazene, [N4P4Cl8], with the difunctional reagent, 2,2'-biphenol, in the presence of potassium carbonate in acetone produced the spiro-substituted derivatives, 2,2'-dioxybiphenylhexachlorocyclotetraphosphazene, bis(2,2'-dioxybiphenyl)tetrachloro-cyclotetraphosphazene, and tris(2,2'-dioxybiphenyl)dichlorocyclotetraphosphazene. Both cis and trans geometrical isomers of the bis compound are observed. Although chromatographic separation of these was unsuccessful, a sample of the trans isomer was obtained by fractional crystallization. The compounds all show non-first-order 31P NMR spectra which were simulated to extract the spectral parameters. Single-crystal X-ray structures of both the trans bis and the tris compounds show that the cyclophosphazene rings exhibit conformational flexibility which gives rise to different crystalline forms being obtained from the same solvent systems. Crystals of trans-bis(2,2'-dioxybiphenyl)tetrachloro-cyclotetraphosphazene were obtained in two different space groups: Pnna (orthorhombic) and P21/n (monoclinic). In the orthorhombic structure, the dominant (72%) conformation of one phosphazene ring is a chair form, and the other (28%) resembles a boat. While for the monoclinic structure, the ring is virtually flat with an oval shape. In both cases the dioxybiphenyl groups are found in R and S configurations in the same molecule and are pi stacked in columns (Pnna) or involved in pi-pi or pi-H interactions (P21/n), thus anchoring the phosphorus atoms of the cyclotetraphosphazenes but still allowing flexibility in the ring conformations. Three crystalline modifications of tris(2,2'-dioxybiphenyl)dichloro-cyclotetraphosphazene were obtained: two in space group P (triclinic), which contained two molecules of dichloromethane in the unit cell, and one solvent-free form in space group P21/n (monoclinic). The cyclophosphazene rings exhibit puckered conformations with the trans-dioxybiphenyl moieties having

  6. Conformal triality of the Kepler problem

    NASA Astrophysics Data System (ADS)

    Cariglia, Marco

    2016-08-01

    We show that the Kepler problem is projectively equivalent to null geodesic motion on the conformal compactification of Minkowski-4 space. This space realises the conformal triality of Minkowski, dS and AdS spaces.

  7. Killing Initial Data on spacelike conformal boundaries

    NASA Astrophysics Data System (ADS)

    Paetz, Tim-Torben

    2016-08-01

    We analyze Killing Initial Data on Cauchy surfaces in conformally rescaled vacuum space-times satisfying Friedrich's conformal field equations. As an application, we derive the KID equations on a spacelike ℐ-.

  8. Gauge natural formulation of conformal gravity

    SciTech Connect

    Campigotto, M.; Fatibene, L.

    2015-03-15

    We consider conformal gravity as a gauge natural theory. We study its conservation laws and superpotentials. We also consider the Mannheim and Kazanas spherically symmetric vacuum solution and discuss conserved quantities associated to conformal and diffeomorphism symmetries.

  9. Boundary terms of conformal anomaly

    NASA Astrophysics Data System (ADS)

    Solodukhin, Sergey N.

    2016-01-01

    We analyze the structure of the boundary terms in the conformal anomaly integrated over a manifold with boundaries. We suggest that the anomalies of type B, polynomial in the Weyl tensor, are accompanied with the respective boundary terms of the Gibbons-Hawking type. Their form is dictated by the requirement that they produce a variation which compensates the normal derivatives of the metric variation on the boundary in order to have a well-defined variational procedure. This suggestion agrees with recent findings in four dimensions for free fields of various spins. We generalize this consideration to six dimensions and derive explicitly the respective boundary terms. We point out that the integrated conformal anomaly in odd dimensions is non-vanishing due to the boundary terms. These terms are specified in three and five dimensions.

  10. Assessment of Chair-side Computer-Aided Design and Computer-Aided Manufacturing Restorations: A Review of the Literature

    PubMed Central

    Baroudi, Kusai; Ibraheem, Shukran Nasser

    2015-01-01

    Background: This paper aimed to evaluate the application of computer-aided design and computer-aided manufacturing (CAD-CAM) technology and the factors that affect the survival of restorations. Materials and Methods: A thorough literature search using PubMed, Medline, Embase, Science Direct, Wiley Online Library and Grey literature were performed from the year 2004 up to June 2014. Only relevant research was considered. Results: The use of chair-side CAD/CAM systems is promising in all dental branches in terms of minimizing time and effort made by dentists, technicians and patients for restoring and maintaining patient oral function and aesthetic, while providing high quality outcome. Conclusion: The way of producing and placing the restorations made with the chair-side CAD/CAM (CEREC and E4D) devices is better than restorations made by conventional laboratory procedures. PMID:25954082

  11. Holographic multiverse and conformal invariance

    SciTech Connect

    Garriga, Jaume; Vilenkin, Alexander E-mail: vilenkin@cosmos.phy.tufts.edu

    2009-11-01

    We consider a holographic description of the inflationary multiverse, according to which the wave function of the universe is interpreted as the generating functional for a lower dimensional Euclidean theory. We analyze a simple model where transitions between inflationary vacua occur through bubble nucleation, and the inflating part of spacetime consists of de Sitter regions separated by thin bubble walls. In this model, we present some evidence that the dual theory is conformally invariant in the UV.

  12. The Conformational Landscape of Serinol

    NASA Astrophysics Data System (ADS)

    Sanz, M. Eugenia; Loru, Donatella; Peña, Isabel; Alonso, José L.

    2014-06-01

    The rotational spectrum of the amino alcohol serinol CH_2OH--CH(NH_2)--CH_2OH, which constitutes the hydrophilic head of the lipid sphingosine, has been investigated using chirped-pulsed Fourier transform microwave spectroscopy in combination with laser ablation Five different forms of serinol have been observed and conclusively identified by the comparison between the experimental values of their rotational and 14N quadrupole coupling constants and those predicted by ab initio calculations. In all observed conformers several hydrogen bonds are established between the two hydroxyl groups and the amino groups in a chain or circular arrangement. The most abundant conformer is stabilised by O--H···N and N--H···O hydrogen bonds forming a chain rather than a cycle. One of the detected conformers presents a tunnelling motion of the hydrogen atoms of the functional groups similar to that observed in glycerol. S. Mata, I. Peña, C. Cabezas, J. C. López, J. L. Alonso, J. Mol. Spectrosc. 2012, 280, 91 V. V. Ilyushin, R. A. Motiyenko, F. J. Lovas, D. F. Plusquellic, J. Mol. Spectrosc. 2008, 251, 129.

  13. Conformational isomerism in 1-heptanal

    NASA Astrophysics Data System (ADS)

    Fisher, Jonathan M.; Xu, Li-Hong; Suenram, R. D.; Pate, Brooks; Douglass, Kevin

    2006-08-01

    The rotational spectrum of 1-heptanal has been recorded over the 10-22 GHz region using a pulsed-molecular-beam, Fourier transform microwave spectrometer. The spectrum has been analyzed using the jb95 spectral analysis program. The spectra of 13 conformational isomers have been identified and assigned in the rich soup of observed transitions. Transitions of these isomers have relative intensities that are well above the intensity level of the onset of 13C isotopomers, which are a factor of 100 down in intensity. In addition to the above 13 isomers, two additional spectra were identified and assigned that belong to dimers that consist of 1-heptanal and one water molecule. In order to map the observed spectra to conformational geometries, high-level ab initio calculations have been carried out. All 15 observed conformers have been associated with ab initio determined structure configurations. In general, the agreement in rotational constants and dipole intensity pattern between the ab initio results and the experimentally observed spectra is quite good.

  14. Conformational Isomerism in 1-Heptanal

    NASA Astrophysics Data System (ADS)

    Fisher, Jonathan M.; Xu, Li-Hong; Suemran, R. D.; Pate, Brooks; Douglass, Kevin

    2006-03-01

    The rotational spectrum of 1-heptanal has been recorded over the 10 GHz to 22 GHz region using a pulsed-molecular-beam, Fourier transform microwave spectrometer. The spectrum has been analyzed using the jb95 spectral analysis program. The spectra of thirteen conformational isomers have been identified and assigned in the rich soup of observed transitions. Transitions of these isomers have relative intensities that are well above the intensity level of the onset of ^13C isotopomers, which are a factor of 100 down in intensity. In addition to the above 13 isomers, two additional spectra were identified and assigned that belong to dimers that consist of 1-heptanal and one water molecule. In order to map the observed spectra to conformational geometries, high-level ab initio calculations have been carried out. All fifteen observed conformers have been associated with ab initio determined structure configurations. In general, the agreement in rotational constants and dipole intensity pattern between the ab initio results and the experimentally observed spectra is quite good.

  15. Conformal Invariance of Graphene Sheets

    PubMed Central

    Giordanelli, I.; Posé, N.; Mendoza, M.; Herrmann, H. J.

    2016-01-01

    Suspended graphene sheets exhibit correlated random deformations that can be studied under the framework of rough surfaces with a Hurst (roughness) exponent 0.72 ± 0.01. Here, we show that, independent of the temperature, the iso-height lines at the percolation threshold have a well-defined fractal dimension and are conformally invariant, sharing the same statistical properties as Schramm-Loewner evolution (SLEκ) curves with κ = 2.24 ± 0.07. Interestingly, iso-height lines of other rough surfaces are not necessarily conformally invariant even if they have the same Hurst exponent, e.g. random Gaussian surfaces. We have found that the distribution of the modulus of the Fourier coefficients plays an important role on this property. Our results not only introduce a new universality class and place the study of suspended graphene membranes within the theory of critical phenomena, but also provide hints on the long-standing question about the origin of conformal invariance in iso-height lines of rough surfaces. PMID:26961723

  16. Conformational kinetics of aliphatic tails

    NASA Astrophysics Data System (ADS)

    Ferrarini, Alberta; Moro, Giorgio; Nordio, Pier Luigi

    The master equation describing the random walk between sites identified with the stable conformers of a chain molecule, represents the extension to the time domain of the Rotational Isomeric State model. The asymptotic analysis of the multidimensional diffusion equation in the continuous torsional variables subjected to the configurational potential, provides a rigorous justification for the discrete models, and it supplies, without resorting to phenomenological parameters, molecular definitions of the kinetic rates for the conformational transitions occurring at each segment of the chain. The coupling between the torsional variables is fully taken into account, giving rise to cooperative effects. A complete calculation of the specific correlation functions which describe the time evolution of the angular functions probed by N.M.R. and dielectric relaxation measurements, has been performed for alkyl chains attached to a massive core. The resulting behaviour has been compared with the decay of trans and gauche populations of specific bonds, expressed in terms of suitable correlation functions whose time integrals lead quite naturally to the definition of effective kinetic constants for the conformational transitions.

  17. Conformal Invariance of Graphene Sheets.

    PubMed

    Giordanelli, I; Posé, N; Mendoza, M; Herrmann, H J

    2016-01-01

    Suspended graphene sheets exhibit correlated random deformations that can be studied under the framework of rough surfaces with a Hurst (roughness) exponent 0.72 ± 0.01. Here, we show that, independent of the temperature, the iso-height lines at the percolation threshold have a well-defined fractal dimension and are conformally invariant, sharing the same statistical properties as Schramm-Loewner evolution (SLEκ) curves with κ = 2.24 ± 0.07. Interestingly, iso-height lines of other rough surfaces are not necessarily conformally invariant even if they have the same Hurst exponent, e.g. random Gaussian surfaces. We have found that the distribution of the modulus of the Fourier coefficients plays an important role on this property. Our results not only introduce a new universality class and place the study of suspended graphene membranes within the theory of critical phenomena, but also provide hints on the long-standing question about the origin of conformal invariance in iso-height lines of rough surfaces. PMID:26961723

  18. Electrophysiological precursors of social conformity.

    PubMed

    Shestakova, Anna; Rieskamp, Jörg; Tugin, Sergey; Ossadtchi, Alexey; Krutitskaya, Janina; Klucharev, Vasily

    2013-10-01

    Humans often change their beliefs or behavior due to the behavior or opinions of others. This study explored, with the use of human event-related potentials (ERPs), whether social conformity is based on a general performance-monitoring mechanism. We tested the hypothesis that conflicts with a normative group opinion evoke a feedback-related negativity (FRN) often associated with performance monitoring and subsequent adjustment of behavior. The experimental results show that individual judgments of facial attractiveness were adjusted in line with a normative group opinion. A mismatch between individual and group opinions triggered a frontocentral negative deflection with the maximum at 200 ms, similar to FRN. Overall, a conflict with a normative group opinion triggered a cascade of neuronal responses: from an earlier FRN response reflecting a conflict with the normative opinion to a later ERP component (peaking at 380 ms) reflecting a conforming behavioral adjustment. These results add to the growing literature on neuronal mechanisms of social influence by disentangling the conflict-monitoring signal in response to the perceived violation of social norms and the neural signal of a conforming behavioral adjustment. PMID:22683703

  19. 21 CFR 886.3130 - Ophthalmic conformer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ophthalmic conformer. 886.3130 Section 886.3130...) MEDICAL DEVICES OPHTHALMIC DEVICES Prosthetic Devices § 886.3130 Ophthalmic conformer. (a) Identification. An ophthalmic conformer is a device usually made of molded plastic intended to be...

  20. On the cohomology of Leibniz conformal algebras

    NASA Astrophysics Data System (ADS)

    Zhang, Jiao

    2015-04-01

    We construct a new cohomology complex of Leibniz conformal algebras with coefficients in a representation instead of a module. The low-dimensional cohomology groups of this complex are computed. Meanwhile, we construct a Leibniz algebra from a Leibniz conformal algebra and prove that the category of Leibniz conformal algebras is equivalent to the category of equivalence classes of formal distribution Leibniz algebras.

  1. An extension theorem for conformal gauge singularities

    SciTech Connect

    Luebbe, Christian; Tod, Paul

    2009-11-15

    We analyze conformal gauge, or isotropic, singularities in cosmological models in general relativity. Using the calculus of tractors, we find conditions in terms of tractor curvature for a local extension of the conformal structure through a cosmological singularity and prove a local extension theorem along a congruence of timelike conformal geodesics.

  2. 40 CFR 52.799 - Transportation conformity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Transportation conformity. 52.799... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.799 Transportation conformity. On June 4, 2010, Indiana submitted the Transportation Conformity Consultation SIP consisting...

  3. 40 CFR 52.799 - Transportation conformity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Transportation conformity. 52.799... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.799 Transportation conformity. On June 4, 2010, Indiana submitted the Transportation Conformity Consultation SIP consisting...

  4. 40 CFR 52.799 - Transportation conformity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Transportation conformity. 52.799... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.799 Transportation conformity. On June 4, 2010, Indiana submitted the Transportation Conformity Consultation SIP consisting...

  5. 40 CFR 52.799 - Transportation conformity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Transportation conformity. 52.799... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Indiana § 52.799 Transportation conformity. On June 4, 2010, Indiana submitted the Transportation Conformity Consultation SIP consisting...

  6. A replicated field intervention study evaluating the impact of a highly adjustable chair and office ergonomics training on visual symptoms☆

    PubMed Central

    Menéndez, Cammie Chaumont; Amick, Benjamin C.; Robertson, Michelle; Bazzani, Lianna; DeRango, Kelly; Rooney, Ted; Moore, Anne

    2016-01-01

    Objective Examine the effects of two office ergonomics interventions in reducing visual symptoms at a private sector worksite. Methods A quasi-experimental study design evaluated the effects of a highly adjustable chair with office ergonomics training intervention (CWT group) and the training only (TO group) compared with no intervention (CO group). Data collection occurred 2 and 1 month(s) pre-intervention and 2, 6 and 12 months post-intervention. During each data collection period, a work environment and health questionnaire (covariates) and daily health diary (outcomes) were completed. Multilevel statistical models tested hypotheses. Results Both the training only intervention (p < 0.001) and the chair with training intervention (p = 0.01) reduced visual symptoms after 12 months. Conclusion The office ergonomics training alone and coupled with a highly adjustable chair reduced visual symptoms. In replicating results from a public sector worksite at a private sector worksite the external validity of the interventions is strengthened, thus broadening its generalizability. PMID:22030069

  7. Vestibulo-Ocular Responses to Vertical Translation using a Hand-Operated Chair as a Field Measure of Otolith Function

    NASA Technical Reports Server (NTRS)

    Wood, S. J.; Campbell, D. J.; Reschke, M. F.; Prather, L.; Clement, G.

    2016-01-01

    The translational Vestibulo-Ocular Reflex (tVOR) is an important otolith-mediated response to stabilize gaze during natural locomotion. One goal of this study was to develop a measure of the tVOR using a simple hand-operated chair that provided passive vertical motion. Binocular eye movements were recorded with a tight-fitting video mask in ten healthy subjects. Vertical motion was provided by a modified spring-powered chair (swopper.com) at approximately 2 Hz (+/- 2 cm displacement) to approximate the head motion during walking. Linear acceleration was measured with wireless inertial sensors (Xsens) mounted on the head and torso. Eye movements were recorded while subjects viewed near (0.5m) and far (approximately 4m) targets, and then imagined these targets in darkness. Subjects also provided perceptual estimates of target distances. Consistent with the kinematic properties shown in previous studies, the tVOR gain was greater with near targets, and greater with vision than in darkness. We conclude that this portable chair system can provide a field measure of otolith-ocular function at frequencies sufficient to elicit a robust tVOR.

  8. X-ray and 1H-NMR spectroscopic studies of the structures and conformations of the new nootropic agents RU-35929, RU-47010 and RU-35965

    NASA Astrophysics Data System (ADS)

    Amato, Maria E.; Bandoli, Giuliano; Casellato, Umberto; Pappalardo, Giuseppe C.; Toja, Emilio

    1990-10-01

    The crystal and molecular structures of the nootropics (±)1-benzenesulphonyl-2-oxo-5-ethoxypyrrolidine ( 1), (±)1-(3-pyridinylsulphonyl)-2-oxo-5-ethoxypyrrolidine ( 2) and (±)1-benzenesulphonyl-2-oxo-5-isopropyloxypyrrolidine ( 3) have been determined by X-ray analysis. The solution conformation of 1, 2 and 3 has been investigated by 1H NMR spectroscopy. In the solid state, the main feature consists of the similar structural parameters and conformations, with the exception of the conformation adopted by the 5-ethoxy moiety which changes on passing from 1 to 2. The solid state overall enveloped conformation of the 2-pyrrolidinone ring for the three nootropics is found to be retained in solution on the basis of NMR evidence. Comparison between calculated and experimental coupling constant values shows that one of the two possible puckered opposite conformational isomers (half-chair shapes) occurs in solution. The relative pharmacological potencies of 1, 2 and 3 cannot therefore be interpreted in terms of the different conformation features presently detectable by available experimental methods.

  9. Leadership strategies for department chairs and program directors: a case study approach.

    PubMed

    Comer, Robert W; Haden, N Karl; Taylor, Robert L; Thomas, D Denee

    2002-04-01

    As a part of the 2000-01 American Dental Education Association (ADEA) Leadership Institute, the Leadership Institute Fellows conducted a faculty development workshop for department chairpersons and program directors during the 2001 ADEA Annual Session. A central premise of the workshop was that successful chairpersons and program directors are both effective leaders and effective managers and that leadership and management involve complementary activities. The workshop was case-based. The ADEA Leadership Institute Fellows developed the cases and led roundtable discussions of each case. A group facilitator led large group debriefings to apply management and leadership theory to each case. The purpose of this paper is to review leadership challenges and management concepts as they were applied in a case-based faculty development workshop. The program was structured to address leadership challenges relating to managing people, mission management, conflict recognition, and conflict management. The cases were developed to relate management theories to situations in academic administration. The situations were designed to encourage debate from numerous perspectives. Each case presented general dilemmas that could be addressed from the vantage point of the dean, chair, or individual faculty member. Reinforcing discussion followed and included identification of central issues, key management concepts, and action alternatives. Because of the breadth of possible discussion, group case analyses at the workshop and in the appended case reviews explore only one perspective. This overview article introduces concepts of leadership and management that provide the foundation for analysis of three case studies that follow. These cases address common leadership and management issues in academic dentistry through three typical cases: the frustrated faculty member (case 1), the misdirected faculty member (case 2), and the faculty member stuck in the middle (case 3). PMID:12014566

  10. Efforts to recover SOHO spacecraft continue as inquiry board co-chairs named

    NASA Astrophysics Data System (ADS)

    1998-06-01

    A team of experts from ESA and Matra Marconi Space, prime contractor for the SOHO spacecraft, gathered at NASA's Goddard Space Flight Center, Greenbelt, MD, to assist the NASA Flight Operations Team in assessing the situation and analysing the spacecraft status should contact be re-established. Engineers are concentrating on gaining a full understanding of the events which led to the loss of signal, information which might help them devise procedures which may recover contact with SOHO. Commands are being sent to SOHO about once per minute through the DSN's 34-meter antennas instructing the spacecraft to activate its transmitters. Based on the last telemetry data received from SOHO, engineers said it appears most likely that the spacecraft is slowly spinning in such a way that its solar arrays, which generate power, either do not faced the Sun at all or do not received adequate sunlight to generate power. However, based on the last data received, it appears that SOHO's solar panels may be exposed to an increasing amount of sunlight each day as it orbits the Sun. If this assumption is correct, within a few weeks enough sunlight might be hitting the solar panels to generate power to charge its batteries. The incident will be the subject of a joint ESA/NASA inquiry board co-chaired by Prof. Massimo Trella, ESA Inspector General and Dr. Michel Greenfield, Deputy Associate Administrator for the Office of Safety and Mission Assurance, NASA Headquarters. The other members of the board will be selected from ESA and NASA as well as from the scientific community. The board is expected to convene later this week at NASA's Goddard Space Flight Center.

  11. Investigation of the role of stereoelectronic effects in the conformation of piperidones by NMR spectroscopy and X-ray diffraction

    PubMed Central

    Garcias-Morales, Cesar; Ortegón-Reyna, David

    2015-01-01

    Summary This paper reports the synthesis of a series of piperidones 1–8 by the Mannich reaction and analysis of their structures and conformations in solution by NMR and mass spectrometry. The six-membered rings in 2,4,6,8-tetraphenyl-3,7-diazabicyclo[3.3.1]nonan-9-ones, compounds 1 and 2, adopt a chair–boat conformation, while those in 2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9-ones, compounds 3–8, adopt a chair–chair conformation because of stereoelectronic effects. These stereoelectronic effects were analyzed by the 1 J C–H coupling constants, which were measured in the 13C satellites of the 1H NMR spectra obtained with the hetero-dqf pulse sequence. In the solid state, these stereoelectronic effects were investigated by measurement of X-ray diffraction data, the molecular geometry (torsional bond angles and bond distances), and inter- and intramolecular interactions, and by natural bond orbital analysis, which was performed using density functional theory at the ωB97XD/6311++G(d,p) level. We found that one of the main factors influencing the conformational stability of 3–8 is the interaction between the lone-pair electrons of nitrogen and the antibonding sigma orbital of C(7)–Heq (nN→σ*C–H(7)eq), a type of hyperconjugative interaction. PMID:26664617

  12. NMR-based conformation and dynamics of a tetrasaccharide-repeating sulfated fucan substituted by different counterions.

    PubMed

    Soares, Paulo A G; Queiroz, Ismael N L; Santos, Gustavo R C; Mourão, Paulo A S; Pomin, Vitor H

    2016-11-01

    The sulfated fucan from the sea urchin Lytechinus variegatus is composed of the repetitive sequence [-3)-α-l-Fucp-4( OSO3-)-(1-3)-α-l-Fucp-2,4-di( OSO3-)-(1-3)-α-l-Fucp-2( OSO3-)-(1-3)-α-l-Fucp-2( OSO3-)-(1-]n . Conformation (of rings and chains) and dynamics of this tetrasaccharide-repeating sulfated fucan substituted by Na(+) , Ca(2+) , and Li(+) as counterions have been examined through experiments of liquid-state nuclear magnetic resonance spectroscopy. Scalar coupling and nuclear Overhauser effect (NOE)-based data have confirmed that all composing units occur as (1) C4 chair conformer regardless of the cation type, unit position within the repeating sequence, and sulfation type. Chain conformation determined by NOE signal pattern assisted by molecular modeling for a theoretical octasaccharide has shown a similar linear 3D structure for the three differently substituted forms. Data derived from spin-relaxation measurements have indicated a contribution of counterion type to dynamics. The calcium-based preparation has shown the highest mobility while the sodiated one showed the lowest mobility. The set of results from this work suggests that counterion type can affect the physicochemical properties of the structurally well-defined sulfated fucan. The counterion effect seems to impact more on the structural mobility than on average conformation of the studied sulfated glycan in solution. PMID:27434759

  13. The biological bases of conformity.

    PubMed

    Morgan, T J H; Laland, K N

    2012-01-01

    Humans are characterized by an extreme dependence on culturally transmitted information and recent formal theory predicts that natural selection should favor adaptive learning strategies that facilitate effective copying and decision making. One strategy that has attracted particular attention is conformist transmission, defined as the disproportionately likely adoption of the most common variant. Conformity has historically been emphasized as significant in the social psychology literature, and recently there have also been reports of conformist behavior in non-human animals. However, mathematical analyses differ in how important and widespread they expect conformity to be, and relevant experimental work is scarce, and generates findings that are both mutually contradictory and inconsistent with the predictions of the models. We review the relevant literature considering the causation, function, history, and ontogeny of conformity, and describe a computer-based experiment on human subjects that we carried out in order to resolve ambiguities. We found that only when many demonstrators were available and subjects were uncertain was subject behavior conformist. A further analysis found that the underlying response to social information alone was generally conformist. Thus, our data are consistent with a conformist use of social information, but as subjects' behavior is the result of both social and asocial influences, the resultant behavior may not be conformist. We end by relating these findings to an embryonic cognitive neuroscience literature that has recently begun to explore the neural bases of social learning. Here conformist transmission may be a particularly useful case study, not only because there are well-defined and tractable opportunities to characterize the biological underpinnings of this form of social learning, but also because early findings imply that humans may possess specific cognitive adaptations for effective social learning. PMID:22712006

  14. Conformance Testing: Measurement Decision Rules

    NASA Technical Reports Server (NTRS)

    Mimbs, Scott M.

    2010-01-01

    The goal of a Quality Management System (QMS) as specified in ISO 9001 and AS9100 is to provide assurance to the customer that end products meet specifications. Measuring devices, often called measuring and test equipment (MTE), are used to provide the evidence of product conformity to specified requirements. Unfortunately, processes that employ MTE can become a weak link to the overall QMS if proper attention is not given to the measurement process design, capability, and implementation. Documented "decision rules" establish the requirements to ensure measurement processes provide the measurement data that supports the needs of the QMS. Measurement data are used to make the decisions that impact all areas of technology. Whether measurements support research, design, production, or maintenance, ensuring the data supports the decision is crucial. Measurement data quality can be critical to the resulting consequences of measurement-based decisions. Historically, most industries required simplistic, one-size-fits-all decision rules for measurements. One-size-fits-all rules in some cases are not rigorous enough to provide adequate measurement results, while in other cases are overly conservative and too costly to implement. Ideally, decision rules should be rigorous enough to match the criticality of the parameter being measured, while being flexible enough to be cost effective. The goal of a decision rule is to ensure that measurement processes provide data with a sufficient level of quality to support the decisions being made - no more, no less. This paper discusses the basic concepts of providing measurement-based evidence that end products meet specifications. Although relevant to all measurement-based conformance tests, the target audience is the MTE end-user, which is anyone using MTE other than calibration service providers. Topics include measurement fundamentals, the associated decision risks, verifying conformance to specifications, and basic measurement

  15. The Biological Bases of Conformity

    PubMed Central

    Morgan, T. J. H.; Laland, K. N.

    2012-01-01

    Humans are characterized by an extreme dependence on culturally transmitted information and recent formal theory predicts that natural selection should favor adaptive learning strategies that facilitate effective copying and decision making. One strategy that has attracted particular attention is conformist transmission, defined as the disproportionately likely adoption of the most common variant. Conformity has historically been emphasized as significant in the social psychology literature, and recently there have also been reports of conformist behavior in non-human animals. However, mathematical analyses differ in how important and widespread they expect conformity to be, and relevant experimental work is scarce, and generates findings that are both mutually contradictory and inconsistent with the predictions of the models. We review the relevant literature considering the causation, function, history, and ontogeny of conformity, and describe a computer-based experiment on human subjects that we carried out in order to resolve ambiguities. We found that only when many demonstrators were available and subjects were uncertain was subject behavior conformist. A further analysis found that the underlying response to social information alone was generally conformist. Thus, our data are consistent with a conformist use of social information, but as subjects’ behavior is the result of both social and asocial influences, the resultant behavior may not be conformist. We end by relating these findings to an embryonic cognitive neuroscience literature that has recently begun to explore the neural bases of social learning. Here conformist transmission may be a particularly useful case study, not only because there are well-defined and tractable opportunities to characterize the biological underpinnings of this form of social learning, but also because early findings imply that humans may possess specific cognitive adaptations for effective social learning. PMID:22712006

  16. Effects of a dynamic chair on pelvic mobility, fatigue, and work efficiency during work performed while sitting: a comparison of dynamic sitting and static sitting

    PubMed Central

    Tanoue, Hironori; Mitsuhashi, Toshitaka; Sako, Shunji; Goto, Ryokichi; Nakai, Tomohiro; Inaba, Ryoichi

    2016-01-01

    [Purpose] Working while sitting for long periods can cause lumbar pain, fatigue, and reduced work efficiency. How a dynamic chair with a seat that moves three-dimensionally affects pelvic mobility before and after work, work efficiency, and post-work fatigue were examined. [Subjects and Methods] Subjects were 17 healthy adults (10 males, 7 females, mean age 21.8 ± 2.7 years). Subjects performed a 30-min Kraepelin test under two conditions: sitting in a standard office chair and sitting in a dynamic sitting balance chair. Root mean square (RMS) values of pelvic movement measured by a triaxial accelerometer during 30 minutes of work, finger-floor distance before and after work, lumbar fatigue, and pelvic movement RMS values during finger-floor distance measurement were used as outcome measures. [Results] Pelvic movement RMS values collected every 5 minutes during 30 minutes of work were significantly higher while sitting in the dynamic balance chair. Changes in pelvic movement RMS values during finger-floor distance measurement after work and amount of work performed during 30 minutes were significantly higher and lumbar fatigue was significantly lower for the dynamic balance chair. [Conclusion] Dynamic sitting maintained or increased pelvic flexibility. The dynamic balance chair may effectively help workers work continuously in seated postures with little fatigue. PMID:27390410

  17. Conformance Verification of Privacy Policies

    NASA Astrophysics Data System (ADS)

    Fu, Xiang

    Web applications are both the consumers and providers of information. To increase customer confidence, many websites choose to publish their privacy protection policies. However, policy conformance is often neglected. We propose a logic based framework for formally specifying and reasoning about the implementation of privacy protection by a web application. A first order extension of computation tree logic is used to specify a policy. A verification paradigm, built upon a static control/data flow analysis, is presented to verify if a policy is satisfied.

  18. Conformational Transitions in Molecular Systems

    NASA Astrophysics Data System (ADS)

    Bachmann, M.; Janke, W.

    2008-11-01

    Proteins are the "work horses" in biological systems. In almost all functions specific proteins are involved. They control molecular transport processes, stabilize the cell structure, enzymatically catalyze chemical reactions; others act as molecular motors in the complex machinery of molecular synthetization processes. Due to their significance, misfolds and malfunctions of proteins typically entail disastrous diseases, such as Alzheimer's disease and bovine spongiform encephalopathy (BSE). Therefore, the understanding of the trinity of amino acid composition, geometric structure, and biological function is one of the most essential challenges for the natural sciences. Here, we glance at conformational transitions accompanying the structure formation in protein folding processes.

  19. Toward TeV Conformality

    SciTech Connect

    Appelquist, T; Avakian, A; Babich, R; Brower, R C; Cheng, M; Clark, M A; Cohen, S D; Fleming, G T; Kiskis, J; Neil, E T; Osborn, J C; Rebbi, C; Schaich, D; Soltz, R; Vranas, P

    2009-11-30

    We study the chiral condensate <{bar {psi}}{psi}> for an SU(3) gauge theory with N{sub f} massless Dirac fermions in the fundamental representation when N{sub f} is increased from 2 to 6. For N{sub f} = 2, our lattice simulations of <{bar {psi}}{psi}>/F{sup 3}, where F is the Nambu-Goldstone-boson decay constant, agree with the measured QCD value. For N{sub f} = 6, this ratio shows significant enhancement, presaging an even larger enhancement anticipated as N{sub f} increases further, toward the critical value for transition from confinement to infrared conformality.

  20. Conformational preferences for some 3-(4‧-substituted phenylsulfonyl)-1-methyl-2-piperidones through spectroscopic and theoretical studies

    NASA Astrophysics Data System (ADS)

    Olivato, Paulo R.; Santos, Jean M. M.; Cerqueira, Carlos R.; Vinhato, Elisângela; Zukerman-Schpector, Julio; Ng, Seik Weng; Tiekink, Edward R. T.; Colle, Maurizio Dal

    2012-11-01

    The analysis of the infrared (IR) carbonyl band of some 3-(4'-substituted phenylsulfonyl)-1-methyl-2-piperidones 1-5 bearing as substituents: OMe 1, Me 2, H 3, Cl 4 and NO25, supported by B3LYP/6-31G(d,p) calculations along with NBO analysis (for 1, 3 and 5) and X-ray diffraction (for 5), indicated the existence of three stable conformations i.e. quasi-axial (q-ax), syn-clinal (s-cl) and quasi-equatorial (q-eq). In the gas phase, the q-ax conformer is calculated as the most stable (ca. 88%) and the least polar, the s-cl conformer is less stable (ca. 12%) but more polar, and the q-eq conformer is the least stable (ca. 1%) and the most polar of the three conformers evaluated. The sum of the most important orbital interactions from NBO analysis and the trend of the electrostatic interactions accounts for the relative populations as well as for the νCO frequencies of the q-ax, s-cl and q-eq conformers calculated in the gas phase. The unique IR νCO band in CCl4 may be ascribed to the most stable q-ax conformer. The more intense (60%) high frequency doublet component in CHCl3 may be assigned to the summing up of the least stable q-eq and the less stable s-cl conformers, as their frequencies are almost coincident. The occurrence of only a single νCO band in both CH2Cl2 and CH3CN supports the fact that the νCO band of the two more polar conformers appear as a single band. Additional support to this rationalization is given by the single point PCM method, which showed a progressive increase of the q-eq + s-cl/q-ax population ratio going from the gas phase to CCl4, to CHCl3, to CH2Cl2 and to CH3CN. X-ray single crystal analysis of 5 indicates that this compound displays a quasi-axial geometry with respect to the [Odbnd Csbnd CHsbnd S] moiety, and that the 2-piperidone ring assumes a slightly distorted half-chair conformation. In the crystal packing, molecules of 5 are arranged into supramolecular layers linked through Csbnd H⋯O interactions along with

  1. Conformal inflation coupled to matter

    SciTech Connect

    Brax, Philippe

    2014-05-01

    We formulate new conformal models of inflation and dark energy which generalise the Higgs-Dilaton scenario. We embed these models in unimodular gravity whose effect is to break scale invariance in the late time Universe. In the early Universe, inflation occurs close to a maximum of both the scalar potential and the scalar coupling to the Ricci scalar in the Jordan frame. At late times, the dilaton, which decouples from the dynamics during inflation, receives a potential term from unimodular gravity and leads to the acceleration of the Universe. We address two central issues in this scenario. First we show that the Damour-Polyalov mechanism, when non-relativistic matter is present prior to the start of inflation, sets the initial conditions for inflation at the maximum of the scalar potential. We then show that conformal invariance implies that matter particles are not coupled to the dilaton in the late Universe at the classical level. When fermions acquire masses at low energy, scale invariance is broken and quantum corrections induce a coupling between the dilaton and matter which is still small enough to evade the gravitational constraints in the solar system.

  2. Conformational gating of DNA conductance

    PubMed Central

    Artés, Juan Manuel; Li, Yuanhui; Qi, Jianqing; Anantram, M. P.; Hihath, Joshua

    2015-01-01

    DNA is a promising molecule for applications in molecular electronics because of its unique electronic and self-assembly properties. Here we report that the conductance of DNA duplexes increases by approximately one order of magnitude when its conformation is changed from the B-form to the A-form. This large conductance increase is fully reversible, and by controlling the chemical environment, the conductance can be repeatedly switched between the two values. The conductance of the two conformations displays weak length dependencies, as is expected for guanine-rich sequences, and can be fit with a coherence-corrected hopping model. These results are supported by ab initio electronic structure calculations that indicate that the highest occupied molecular orbital is more disperse in the A-form DNA case. These results demonstrate that DNA can behave as a promising molecular switch for molecular electronics applications and also provide additional insights into the huge dispersion of DNA conductance values found in the literature. PMID:26648400

  3. Metrics with Galilean conformal isometry

    SciTech Connect

    Bagchi, Arjun; Kundu, Arnab

    2011-03-15

    The Galilean conformal algebra (GCA) arises in taking the nonrelativistic limit of the symmetries of a relativistic conformal field theory in any dimensions. It is known to be infinite dimensional in all spacetime dimensions. In particular, the 2d GCA emerges out of a scaling limit of linear combinations of two copies of the Virasoro algebra. In this paper, we find metrics in dimensions greater than 2 which realize the finite 2d GCA (the global part of the infinite algebra) as their isometry by systematically looking at a construction in terms of cosets of this finite algebra. We list all possible subalgebras consistent with some physical considerations motivated by earlier work in this direction and construct all possible higher-dimensional nondegenerate metrics. We briefly study the properties of the metrics obtained. In the standard one higher-dimensional ''holographic'' setting, we find that the only nondegenerate metric is Minkowskian. In four and five dimensions, we find families of nontrivial metrics with a rather exotic signature. A curious feature of these metrics is that all but one of them are Ricci-scalar flat.

  4. Quantifying macromolecular conformational transition pathways

    NASA Astrophysics Data System (ADS)

    Seyler, Sean; Kumar, Avishek; Thorpe, Michael; Beckstein, Oliver

    2015-03-01

    Diverse classes of proteins function through large-scale conformational changes that are challenging for computer simulations. A range of fast path-sampling techniques have been used to generate transitions, but it has been difficult to compare paths from (and assess the relative strengths of) different methods. We introduce a comprehensive method (pathway similarity analysis, PSA) for quantitatively characterizing and comparing macromolecular pathways. The Hausdorff and Fréchet metrics (known from computational geometry) are used to quantify the degree of similarity between polygonal curves in configuration space. A strength of PSA is its use of the full information available from the 3 N-dimensional configuration space trajectory without requiring additional specific knowledge about the system. We compare a sample of eleven different methods for the closed-to-open transitions of the apo enzyme adenylate kinase (AdK) and also apply PSA to an ensemble of 400 AdK trajectories produced by dynamic importance sampling MD and the Geometrical Pathways algorithm. We discuss the method's potential to enhance our understanding of transition path sampling methods, validate them, and help guide future research toward deeper physical insights into conformational transitions.

  5. Conformational gating of DNA conductance.

    PubMed

    Artés, Juan Manuel; Li, Yuanhui; Qi, Jianqing; Anantram, M P; Hihath, Joshua

    2015-01-01

    DNA is a promising molecule for applications in molecular electronics because of its unique electronic and self-assembly properties. Here we report that the conductance of DNA duplexes increases by approximately one order of magnitude when its conformation is changed from the B-form to the A-form. This large conductance increase is fully reversible, and by controlling the chemical environment, the conductance can be repeatedly switched between the two values. The conductance of the two conformations displays weak length dependencies, as is expected for guanine-rich sequences, and can be fit with a coherence-corrected hopping model. These results are supported by ab initio electronic structure calculations that indicate that the highest occupied molecular orbital is more disperse in the A-form DNA case. These results demonstrate that DNA can behave as a promising molecular switch for molecular electronics applications and also provide additional insights into the huge dispersion of DNA conductance values found in the literature. PMID:26648400

  6. Conformational Properties of 1-Halogenated-1-Silacyclohexanes, C5H10SiHX (X = Cl, Br, I): Gas Electron Diffraction, Low-Temperature NMR, Temperature-Dependent Raman Spectroscopy, and Quantum-Chemical Calculations.

    PubMed

    Wallevik, Sunna Ó; Bjornsson, Ragnar; Kvaran, Agúst; Jonsdottir, Sigridur; Arnason, Ingvar; Belyakov, Alexander V; Kern, Thomas; Hassler, Karl

    2013-12-01

    The molecular structures of axial and equatorial conformers of cyclo-C5H10SiHX (X = Cl, Br, I) as well as the thermodynamic equilibrium between these species was investigated by means of gas electron diffraction, dynamic nuclear magnetic resonance, temperature-dependent Raman spectroscopy, and quantum-chemical calculations applying CCSD(T), MP2, and DFT methods. According to the experimental and calculated results, all three compounds exist as a mixture of two chair conformers of the six-membered ring. The two chair forms of Cs symmetry differ in the axial or equatorial position of the X atom. In all cases, the axial conformer is preferred over the equatorial one. When the experimental uncertainties are taken into account, all of the experimental and theoretical results for the conformational energy (E axial - E equatorial) fit into a remarkably narrow range of -0.50 ± 0.15 kcal mol(-1). It was found by NBO analysis that the axial conformers are unfavorable in terms of steric energy and conjugation effects and that they are stabilized mainly by electrostatic interactions. The conformational energies for C6H11X and cyclo-C5H10SiHX (X = F, Cl, Br, I, At) were compared using CCSD(T) calculations. In both series, fluorine is predicted to have a lower conformational preference (cyclohexane equatorial, silacyclohexane axial) than Cl, Br, and I. It is predicted that astatine would behave very similarly to Cl, Br, and I within each series. PMID:24353364

  7. Conformational Properties of 1-Halogenated-1-Silacyclohexanes, C5H10SiHX (X = Cl, Br, I): Gas Electron Diffraction, Low-Temperature NMR, Temperature-Dependent Raman Spectroscopy, and Quantum-Chemical Calculations†

    PubMed Central

    2013-01-01

    The molecular structures of axial and equatorial conformers of cyclo-C5H10SiHX (X = Cl, Br, I) as well as the thermodynamic equilibrium between these species was investigated by means of gas electron diffraction, dynamic nuclear magnetic resonance, temperature-dependent Raman spectroscopy, and quantum-chemical calculations applying CCSD(T), MP2, and DFT methods. According to the experimental and calculated results, all three compounds exist as a mixture of two chair conformers of the six-membered ring. The two chair forms of Cs symmetry differ in the axial or equatorial position of the X atom. In all cases, the axial conformer is preferred over the equatorial one. When the experimental uncertainties are taken into account, all of the experimental and theoretical results for the conformational energy (Eaxial – Eequatorial) fit into a remarkably narrow range of −0.50 ± 0.15 kcal mol–1. It was found by NBO analysis that the axial conformers are unfavorable in terms of steric energy and conjugation effects and that they are stabilized mainly by electrostatic interactions. The conformational energies for C6H11X and cyclo-C5H10SiHX (X = F, Cl, Br, I, At) were compared using CCSD(T) calculations. In both series, fluorine is predicted to have a lower conformational preference (cyclohexane equatorial, silacyclohexane axial) than Cl, Br, and I. It is predicted that astatine would behave very similarly to Cl, Br, and I within each series. PMID:24353364

  8. Insights into How Cyclic Peptides Switch Conformations.

    PubMed

    McHugh, Sean M; Rogers, Julia R; Yu, Hongtao; Lin, Yu-Shan

    2016-05-10

    Cyclic peptides have recently emerged as promising modulators of protein-protein interactions. However, it is currently highly difficult to predict the structures of cyclic peptides owing to their rugged conformational free energy landscape, which prevents sampling of all thermodynamically relevant conformations. In this article, we first investigate how a relatively flexible cyclic hexapeptide switches conformations. It is found that, although the circular geometry of small cyclic peptides of size 6-8 may require rare, coherent dihedral changes to sample a new conformation, the changes are rather local, involving simultaneous changes of ϕi and ψi or ψi and ϕi+1. The understanding of how these cyclic peptides switch conformations enables the use of metadynamics simulations with reaction coordinates specifically targeting such coupled two-dihedral changes to effectively sample cyclic peptide conformational space. PMID:27031286

  9. Conformal Electromagnetic Particle in Cell: A Review

    SciTech Connect

    Meierbachtol, Collin S.; Greenwood, Andrew D.; Verboncoeur, John P.; Shanker, Balasubramaniam

    2015-10-26

    We review conformal (or body-fitted) electromagnetic particle-in-cell (EM-PIC) numerical solution schemes. Included is a chronological history of relevant particle physics algorithms often employed in these conformal simulations. We also provide brief mathematical descriptions of particle-tracking algorithms and current weighting schemes, along with a brief summary of major time-dependent electromagnetic solution methods. Several research areas are also highlighted for recommended future development of new conformal EM-PIC methods.

  10. Evolutionary Conserved Positions Define Protein Conformational Diversity.

    PubMed

    Saldaño, Tadeo E; Monzon, Alexander M; Parisi, Gustavo; Fernandez-Alberti, Sebastian

    2016-03-01

    Conformational diversity of the native state plays a central role in modulating protein function. The selection paradigm sustains that different ligands shift the conformational equilibrium through their binding to highest-affinity conformers. Intramolecular vibrational dynamics associated to each conformation should guarantee conformational transitions, which due to its importance, could possibly be associated with evolutionary conserved traits. Normal mode analysis, based on a coarse-grained model of the protein, can provide the required information to explore these features. Herein, we present a novel procedure to identify key positions sustaining the conformational diversity associated to ligand binding. The method is applied to an adequate refined dataset of 188 paired protein structures in their bound and unbound forms. Firstly, normal modes most involved in the conformational change are selected according to their corresponding overlap with structural distortions introduced by ligand binding. The subspace defined by these modes is used to analyze the effect of simulated point mutations on preserving the conformational diversity of the protein. We find a negative correlation between the effects of mutations on these normal mode subspaces associated to ligand-binding and position-specific evolutionary conservations obtained from multiple sequence-structure alignments. Positions whose mutations are found to alter the most these subspaces are defined as key positions, that is, dynamically important residues that mediate the ligand-binding conformational change. These positions are shown to be evolutionary conserved, mostly buried aliphatic residues localized in regular structural regions of the protein like β-sheets and α-helix. PMID:27008419

  11. Computing conformational free energy by deactivated morphing.

    SciTech Connect

    Park, S.; Lau, A. Y.; Roux, B.; Univ. of Chicago

    2008-10-07

    Despite the significant advances in free-energy computations for biomolecules, there exists no general method to evaluate the free-energy difference between two conformations of a macromolecule that differ significantly from each other. A crucial ingredient of such a method is the ability to find a path between different conformations that allows an efficient computation of the free energy. In this paper, we introduce a method called 'deactivated morphing', in which one conformation is morphed into another after the internal interactions are completely turned off. An important feature of this method is the (shameless) use of nonphysical paths, which makes the method robustly applicable to conformational changes of arbitrary complexity.

  12. Evolutionary Conserved Positions Define Protein Conformational Diversity

    PubMed Central

    Saldaño, Tadeo E.; Monzon, Alexander M.; Parisi, Gustavo; Fernandez-Alberti, Sebastian

    2016-01-01

    Conformational diversity of the native state plays a central role in modulating protein function. The selection paradigm sustains that different ligands shift the conformational equilibrium through their binding to highest-affinity conformers. Intramolecular vibrational dynamics associated to each conformation should guarantee conformational transitions, which due to its importance, could possibly be associated with evolutionary conserved traits. Normal mode analysis, based on a coarse-grained model of the protein, can provide the required information to explore these features. Herein, we present a novel procedure to identify key positions sustaining the conformational diversity associated to ligand binding. The method is applied to an adequate refined dataset of 188 paired protein structures in their bound and unbound forms. Firstly, normal modes most involved in the conformational change are selected according to their corresponding overlap with structural distortions introduced by ligand binding. The subspace defined by these modes is used to analyze the effect of simulated point mutations on preserving the conformational diversity of the protein. We find a negative correlation between the effects of mutations on these normal mode subspaces associated to ligand-binding and position-specific evolutionary conservations obtained from multiple sequence-structure alignments. Positions whose mutations are found to alter the most these subspaces are defined as key positions, that is, dynamically important residues that mediate the ligand-binding conformational change. These positions are shown to be evolutionary conserved, mostly buried aliphatic residues localized in regular structural regions of the protein like β-sheets and α-helix. PMID:27008419

  13. Conformation of liquid N-alkanes.

    PubMed Central

    Goodsaid-Zalduondo, F; Engelman, D M

    1981-01-01

    The conformations of liquid n-alkanes have been studied using neutron scattering techniques to better understand the conformational forces present in membrane lipid interiors. We have studied hydrocarbon chains having lengths comparable to those found for esterified membrane lipid fatty acids, and find that the steric constraints of packing in the liquid state do not change the conformational distributions of hydrocarbon chains from those imposed by the intrachain forces present in the gas phase. It follows that the central region of membranes containing lipids in the disordered state should contain hydrocarbon chain conformations determined primarily by intrachain forces. PMID:7272453

  14. Fabrication challenges associated with conformal optics

    NASA Astrophysics Data System (ADS)

    Schaefer, John; Eichholtz, Richard A.; Sulzbach, Frank C.

    2001-09-01

    A conformal optic is typically an optical window that conforms smoothly to the external shape of a system platform to improve aerodynamics. Conformal optics can be on-axis, such as an ogive missile dome, or off-axis, such as in a free form airplane wing. A common example of conformal optics is the automotive head light window that conforms to the body of the car aerodynamics and aesthetics. The unusual shape of conformal optics creates tremendous challenges for design, manufacturing, and testing. This paper will discuss fabrication methods that have been successfully demonstrated to produce conformal missile domes and associated wavefront corrector elements. It will identify challenges foreseen with more complex free-form configurations. Work presented in this paper was directed by the Precision Conformal Optics Consortium (PCOT). PCOT is comprised of both industrial and academic members who teamed to develop and demonstrate conformal optical systems suitable for insertion into future military programs. The consortium was funded under DARPA agreement number MDA972-96-9-08000.

  15. Rotational Spectroscopy Unveils Eleven Conformers of Adrenaline

    NASA Astrophysics Data System (ADS)

    Cabezas, C.; Cortijo, V.; Mata, S.; Lopez, J. C.; Alonso, J. L.

    2013-06-01

    Recent improvements in our LA-MB-FTMW instrumentation have allowed the characterization of eleven and eight conformers for the neurotransmitters adrenaline and noradrenaline respectively. The observation of this rich conformational behavior is in accordance with the recent observation of seven conformers for dopamine and in sharp contrast with the conformational reduction proposed for catecholamines. C. Cabezas, I. Peña, J. C. López, J. L. Alonso J. Phys. Chem. Lett. 2013, 4, 486. H. Mitsuda, M. Miyazaki, I. B. Nielsen, P. Carcabal,C. Dedonder, C. Jouvet, S. Ishiuchi, M. Fujii J. Phys. Chem. Lett. 2010, 1, 1130.

  16. Logarithmic operators and logarithmic conformal field theories

    NASA Astrophysics Data System (ADS)

    Gurarie, Victor

    2013-12-01

    Logarithmic operators and logarithmic conformal field theories are reviewed. Prominent examples considered here include c = -2 and c = 0 logarithmic conformal field theories. c = 0 logarithmic conformal field theories are especially interesting since they describe some of the critical points of a variety of longstanding problems involving a two dimensional quantum particle moving in a spatially random potential, as well as critical two dimensional self-avoiding random walks and percolation. Lack of classification of logarithmic conformal field theories remains a major impediment to progress towards finding complete solutions to these problems.

  17. Conformable eddy current array delivery

    NASA Astrophysics Data System (ADS)

    Summan, Rahul; Pierce, Gareth; Macleod, Charles; Mineo, Carmelo; Riise, Jonathan; Morozov, Maxim; Dobie, Gordon; Bolton, Gary; Raude, Angélique; Dalpé, Colombe; Braumann, Johannes

    2016-02-01

    The external surface of stainless steel containers used for the interim storage of nuclear material may be subject to Atmospherically Induced Stress Corrosion Cracking (AISCC). The inspection of such containers poses a significant challenge due to the large quantities involved; therefore, automating the inspection process is of considerable interest. This paper reports upon a proof-of-concept project concerning the automated NDT of a set of test containers containing artificially generated AISCCs. An Eddy current array probe with a conformable padded surface from Eddyfi was used as the NDT sensor and end effector on a KUKA KR5 arc HW robot. A kinematically valid cylindrical raster scan path was designed using the KUKA|PRC path planning software. Custom software was then written to interface measurement acquisition from the Eddyfi hardware with the motion control of the robot. Preliminary results and analysis are presented from scanning two canisters.

  18. Conformal frame dependence of inflation

    NASA Astrophysics Data System (ADS)

    Domènech, Guillem; Sasaki, Misao

    2015-04-01

    Physical equivalence between different conformal frames in scalar-tensor theory of gravity is a known fact. However, assuming that matter minimally couples to the metric of a particular frame, which we call the matter Jordan frame, the matter point of view of the universe may vary from frame to frame. Thus, there is a clear distinction between gravitational sector (curvature and scalar field) and matter sector. In this paper, focusing on a simple power-law inflation model in the Einstein frame, two examples are considered; a super-inflationary and a bouncing universe Jordan frames. Then we consider a spectator curvaton minimally coupled to a Jordan frame, and compute its contribution to the curvature perturbation power spectrum. In these specific examples, we find a blue tilt at short scales for the super-inflationary case, and a blue tilt at large scales for the bouncing case.

  19. Approaching Conformality with Ten Flavors

    SciTech Connect

    Appelquist, Thomas; Brower, Richard C.; Buchoff, Michael I.; Cheng, Michael; Cohen, Saul D.; Fleming, George T.; Kiskis, Joe; Lin, Meifeng; Na, Heechang; Neil, Ethan T.; Osborn, James C.

    2012-04-01

    We present first results for lattice simulations, on a single volume, of the low-lying spectrum of an SU(3) Yang-Mills gauge theory with N{sub f} = 10 light fermions in the fundamental representation. Fits to the fermion mass dependence of various observables are found to be globally consistent with the hypothesis that this theory is within or just outside the strongly-coupled edge of the conformal window, with mass anomalous dimension {gamma}* {approx} 1 over the range of scales simulated. We stress that we cannot rule out the possibility of spontaneous chiral-symmetry breaking at scales well below our infrared cutoff. We discuss important systematic effects, including finite-volume corrections, and consider directions for future improvement.

  20. Electromagnetic characterization of conformal antennas

    NASA Technical Reports Server (NTRS)

    Volakis, John L.; Kempel, Leo C.; Alexanian, Angelos; Jin, J. M.; Yu, C. L.; Woo, Alex C.

    1992-01-01

    The ultimate objective of this project is to develop a new technique which permits an accurate simulation of microstrip patch antennas or arrays with various feed, superstrate and/or substrate configurations residing in a recessed cavity whose aperture is planar, cylindrical or otherwise conformed to the substructure. The technique combines the finite element and boundary integral methods to formulate a system suitable for solution via the conjugate gradient method in conjunction with the fast Fourier transform. The final code is intended to compute both scattering and radiation patterns of the structure with an affordable memory demand. With upgraded capabilities, the four included papers examined the radar cross section (RCS), input impedance, gain, and resonant frequency of several rectangular configurations using different loading and substrate/superstrate configurations.

  1. Conformal approach to cylindrical DLA

    NASA Astrophysics Data System (ADS)

    Taloni, A.; Caglioti, E.; Loreto, V.; Pietronero, L.

    2006-09-01

    We extend the conformal mapping approach elaborated for the radial diffusion limited aggregation model (DLA) to cylindrical geometry. We introduce in particular a complex function which allows a cylindrical cluster to be grown using as an intermediate step a radial aggregate. The aggregate grown exhibits the same self-affine features as the original cylindrical DLA. The specific choice of the transformation allows us to study the relationship between the radial and the cylindrical geometry. In particular the cylindrical aggregate can be seen as a radial aggregate with particles of size increasing with the radius. On the other hand, the radial aggregate can be seen as a cylindrical aggregate with particles of size decreasing with the height. This framework, which shifts the point of view from the geometry to the size of the particles, can open the way to more quantitative studies on the relationship between radial and cylindrical DLA.

  2. Structural, conformational, theoretical and pharmacological study of some amides derived from 3,7-dimethyl-9-[( N-substituted)-4-chlorobenzamido]3,7-diazabicyclo[3.3.1]nonane-9-carboxamide

    NASA Astrophysics Data System (ADS)

    Fernández, M. J.; Toledano, M. S.; Gálvez, E.; Orjales, A.; Berisa, A.; Labeaga, L.; Fonseca, I.; Sanz-Aparicio, J.; Bellanato, J.

    1995-06-01

    A series of 3,7-dimethyl-9-[( N-substituted)-4-chlorobenzamido]-3,7-diazabicyclo[3.3.1]nonane-9-carboxamides 1-3 have been synthesized and studied by infrared, Raman, 1H and 13C NMR spectroscopy and molecular modeling techniques. The crystal structure of 3,7-dimethyl-9-[( N-benzyl)-4-chlorobenzamido]-3,7-diazabicyclo[3.3.1]nonane-9-carboxamide ( 2) was determined by X-ray diffraction. In CDCl 3 and CD 3OD solutions, these compounds adopt a non-distorted chair-chair conformation with the N-substituents in an equatorial position. Compound 2 prevented acetic acid induced writhing in mice.

  3. Synthesis, structural, conformational and pharmacological study of some amides derived from 3 -methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-amine

    NASA Astrophysics Data System (ADS)

    Iriepa, I.; Bellanato, J.; Gálvez, E.; Gil-Alberdi, B.

    2010-07-01

    Some mono-substituted amides ( 2- 5) derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-amine were synthesized and studied by IR, 1H and 13C NMR spectroscopy. The crystal structure of 3-methyl-2,4-diphenyl-9α-(3,5-dichlorobenzamido)-3-azabicyclo[3.3.1]nonane ( 3) was determined by X-ray diffraction. NMR data showed that all compounds adopt in CDCl 3 a preferred flattened chair-chair conformation with the N-CH 3 group in equatorial disposition. X-ray data agreed with this conformation in the case of compound 3. IR data revealed that compounds 2 and 3 present a C dbnd O⋯HN intermolecular bond in the solid state. This conclusion was also confirmed by X-ray data of compound 3. In the case of compound 5, IR results suggested intermolecular NH⋯N-heterocyclic bonding. On the contrary, in the pyrazine derivative ( 4), IR, 1H and 13C NMR data showed the presence of an intramolecular NH⋯N1″-heterocyclic hydrogen bond in the solid state and solution. Moreover, NMR and IR data showed a preferred trans disposition for the NH-C dbnd O group. NMR also revealed free rotation of the -NH-CO-R group around C9-NH bond. Pharmacological assays on mice were drawn to evaluate analgesic activity.

  4. Situating the Embodied Mind in a Landscape of Standing Affordances for Living Without Chairs: Materializing a Philosophical Worldview.

    PubMed

    Rietveld, Erik

    2016-07-01

    Sitting too much is unhealthy, but a widespread habit in many societies. Realizing behavioral change in this area is hard. Our societies promote being seated via the way its places are structured: they are filled with chairs for example. How can we make healthier environments that invite people to move around more? This article shows how philosophical research in the area of embodied/enactive cognitive science let to a built vision for the office of the future, of 2025. Multidisciplinary studio RAAAF [Rietveld Architecture-Art-Affordances] and visual artist Barbara Visser built this world without chairs, titled The End of Sitting. This large rock-like landscape integrates many affordances for standing. Affordances are the possibilities for action provided by the environment. This landscape of standing affordances allows people to work standing while being supported by the material structure of the environment. This unorthodox working landscape is both an enactive art installation and the materialization of a philosophical worldview that understands people as embodied minds situated in a landscape of affordances. It stimulates reflection on the way built environments can naturally invite more active and healthy behavior. PMID:26988344

  5. The chair of mental and brain diseases: Charcot's pupils--Benjamin Ball, Alix Joffroy and Gilbert Ballet.

    PubMed

    Tiberghien, Denis

    2011-01-01

    Benjamin Ball (1833-1893), Alix Joffroy (1844-1908) and Gilbert Ballet (1853-1916) were three pupils of the great Charcot (1825-1893). They were successive holders of the chair for mental illness and encephalon at its creation in 1877 until the First World War: Benjamin Ball from 1877 to 1893, Alix Joffroy from 1893 to 1908, and Gilbert Ballet from 1908 to 1916. After describing the context surrounding the creation of this chair and the choice of its representative and successors, we will examine their neurological work on the brain derived from a method influenced by a current of thought careful to list the symptoms of the disease and to look for the anatomical causes in the brain. The renowned 19th century French neurologist Jean-Martin Charcot was a huge influence. With their acquired experience and progress in the fields of morphology and histology and cerebral cortex functioning, they greatly contributed to the evolution of neurological, clinical anatomical and psychological-physiological findings--thus allowing certain pathologies to be considered as organic diseases rather than neurotic symptoms--while all the time recognizing the importance of the cortical cell in mental illness. PMID:20938145

  6. Specialization and generalization in the diversification of phytophagous insects: tests of the musical chairs and oscillation hypotheses

    PubMed Central

    Hardy, Nate B.; Otto, Sarah P.

    2014-01-01

    Evolutionary biologists have often assumed that ecological generalism comes at the expense of less intense exploitation of specific resources and that this trade-off will promote the evolution of ecologically specialized daughter species. Using a phylogenetic comparative approach with butterflies as a model system, we test hypotheses that incorporate changes in niche breadth and location into explanations of the taxonomic diversification of insect herbivores. Specifically, we compare the oscillation hypothesis, where speciation is driven by host-plant generalists giving rise to specialist daughter species, to the musical chairs hypothesis, where speciation is driven by host-plant switching, without changes in niche breadth. Contrary to the predictions of the oscillation hypothesis, we recover a negative relationship between host-plant breadth and diversification rate and find that changes in host breadth are seldom coupled to speciation events. By contrast, we present evidence for a positive relationship between rates of host switching and butterfly diversification, consonant with the musical chairs hypothesis. These results suggest that the costs of trophic generalism in plant-feeding insects may have been overvalued and that transitions from generalists to ecological specialists may not be an important driver of speciation in general. PMID:25274368

  7. 40 CFR 93.154 - Conformity analysis.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Conformity analysis. 93.154 Section 93... General Federal Actions to State or Federal Implementation Plans § 93.154 Conformity analysis. Any Federal... choose to adopt the analysis of another Federal agency or develop its own analysis in order to make...

  8. 40 CFR 51.854 - Conformity analysis.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Conformity analysis. 51.854 Section 51... Federal Actions to State or Federal Implementation Plans § 51.854 Conformity analysis. Link to an... for various aspects of a project, a Federal agency may choose to adopt the analysis of another...

  9. Conformity to Peer Pressure in Preschool Children

    ERIC Educational Resources Information Center

    Haun, Daniel B. M.; Tomasello, Michael

    2011-01-01

    Both adults and adolescents often conform their behavior and opinions to peer groups, even when they themselves know better. The current study investigated this phenomenon in 24 groups of 4 children between 4;2 and 4;9 years of age. Children often made their judgments conform to those of 3 peers, who had made obviously erroneous but unanimous…

  10. CCProf: exploring conformational change profile of proteins

    PubMed Central

    Chang, Che-Wei; Chou, Chai-Wei; Chang, Darby Tien-Hao

    2016-01-01

    In many biological processes, proteins have important interactions with various molecules such as proteins, ions or ligands. Many proteins undergo conformational changes upon these interactions, where regions with large conformational changes are critical to the interactions. This work presents the CCProf platform, which provides conformational changes of entire proteins, named conformational change profile (CCP) in the context. CCProf aims to be a platform where users can study potential causes of novel conformational changes. It provides 10 biological features, including conformational change, potential binding target site, secondary structure, conservation, disorder propensity, hydropathy propensity, sequence domain, structural domain, phosphorylation site and catalytic site. All these information are integrated into a well-aligned view, so that researchers can capture important relevance between different biological features visually. The CCProf contains 986 187 protein structure pairs for 3123 proteins. In addition, CCProf provides a 3D view in which users can see the protein structures before and after conformational changes as well as binding targets that induce conformational changes. All information (e.g. CCP, binding targets and protein structures) shown in CCProf, including intermediate data are available for download to expedite further analyses. Database URL: http://zoro.ee.ncku.edu.tw/ccprof/ PMID:27016699

  11. Conformational Sampling of Peptides in Cellular Environments☆

    PubMed Central

    Tanizaki, Seiichiro; Clifford, Jacob; Connelly, Brian D.; Feig, Michael

    2008-01-01

    Abstract Biological systems provide a complex environment that can be understood in terms of its dielectric properties. High concentrations of macromolecules and cosolvents effectively reduce the dielectric constant of cellular environments, thereby affecting the conformational sampling of biomolecules. To examine this effect in more detail, the conformational preference of alanine dipeptide, poly-alanine, and melittin in different dielectric environments is studied with computer simulations based on recently developed generalized Born methodology. Results from these simulations suggest that extended conformations are favored over α-helical conformations at the dipeptide level at and below dielectric constants of 5–10. Furthermore, lower-dielectric environments begin to significantly stabilize helical structures in poly-alanine at ɛ = 20. In the more complex peptide melittin, different dielectric environments shift the equilibrium between two main conformations: a nearly fully extended helix that is most stable in low dielectrics and a compact, V-shaped conformation consisting of two helices that is preferred in higher dielectric environments. An additional conformation is only found to be significantly populated at intermediate dielectric constants. Good agreement with previous studies of different peptides in specific, less-polar solvent environments, suggest that helix stabilization and shifts in conformational preferences in such environments are primarily due to a reduced dielectric environment rather than specific molecular details. The findings presented here make predictions of how peptide sampling may be altered in dense cellular environments with reduced dielectric response. PMID:17905846

  12. Regulatory Conformance Checking: Logic and Logical Form

    ERIC Educational Resources Information Center

    Dinesh, Nikhil

    2010-01-01

    We consider the problem of checking whether an organization conforms to a body of regulation. Conformance is studied in a runtime verification setting. The regulation is translated to a logic, from which we synthesize monitors. The monitors are evaluated as the state of an organization evolves over time, raising an alarm if a violation is…

  13. Conformational readout of RNA by small ligands

    PubMed Central

    Kligun, Efrat; Mandel-Gutfreund, Yael

    2013-01-01

    RNA molecules have highly versatile structures that can fold into myriad conformations, providing many potential pockets for binding small molecules. The increasing number of available RNA structures, in complex with proteins, small ligands and in free form, enables the design of new therapeutically useful RNA-binding ligands. Here we studied RNA ligand complexes from 10 RNA groups extracted from the protein data bank (PDB), including adaptive and non-adaptive complexes. We analyzed the chemical, physical, structural and conformational properties of binding pockets around the ligand. Comparing the properties of ligand-binding pockets to the properties of computed pockets extracted from all available RNA structures and RNA-protein interfaces, revealed that ligand-binding pockets, mainly the adaptive pockets, are characterized by unique properties, specifically enriched in rare conformations of the nucleobase and the sugar pucker. Further, we demonstrate that nucleotides possessing the rare conformations are preferentially involved in direct interactions with the ligand. Overall, based on our comprehensive analysis of RNA-ligand complexes, we suggest that the unique conformations adopted by RNA nucleotides play an important role in RNA recognition by small ligands. We term the recognition of a binding site by a ligand via the unique RNA conformations “RNA conformational readout.” We propose that “conformational readout” is a general way by which RNA binding pockets are recognized and selected from an ensemble of different RNA states. PMID:23618839

  14. Technidilaton at the conformal edge

    SciTech Connect

    Hashimoto, Michio; Yamawaki, Koichi

    2011-01-01

    Technidilaton (TD) was proposed long ago in the technicolor near criticality/conformality. To reveal the critical behavior of TD, we explicitly compute the nonperturbative contributions to the scale anomaly <{theta}{sub {mu}}{sup {mu}>} and to the technigluon condensate <{alpha}G{sub {mu}{nu}}{sup 2}>, which are generated by the dynamical mass m of the technifermions. Our computation is based on the (improved) ladder Schwinger-Dyson equation, with the gauge coupling {alpha} replaced by the two-loop running coupling {alpha}({mu}) having the Caswell-Banks-Zaks infrared fixed point {alpha}{sub *}: {alpha}({mu}){approx_equal}{alpha}={alpha}{sub *} for the infrared region m<{mu}<{Lambda}{sub TC}, where {Lambda}{sub TC} is the intrinsic scale (analogue of {Lambda}{sub QCD} of QCD) relevant to the perturbative scale anomaly. We find that -<{theta}{sub {mu}}{sup {mu}}>/m{sup 4}{yields}const{ne}0 and <{alpha}G{sub {mu}}{nu}{sup 2}>/m{sup 4}{yields}({alpha}/{alpha}{sub cr}-1){sup -3/2}{yields}{infinity} in the criticality limit m/{Lambda}{sub TC}{approx}exp(-{pi}/({alpha}/{alpha}{sub cr}-1){sup 1/2}){yields}0 ({alpha}={alpha}{sub *}=>{alpha}{sub cr}, or N{sub f} approaches N{sub f}{sup cr}) ('conformal edge'). Our result precisely reproduces the formal identity <{theta}{sub {mu}}{sup {mu}>}=({beta}({alpha})/4{alpha}{sup 2})<{alpha}G{sub {mu}{nu}}{sup 2}>, where {beta}({alpha})={Lambda}{sub TC}({partial_derivative}{alpha}/{partial_derivative}{Lambda}{sub TC})=-(2{alpha}{sub cr}/{pi}){center_dot}({alpha}/{alpha}{sub cr}-1){sup 3/2} is the nonperturbative beta function corresponding to the above essential singularity scaling of m/{Lambda}{sub TC}. Accordingly, the partially conserved dilatation current implies (M{sub TD}/m){sup 2}(F{sub TD}/m){sup 2}=-4<{theta}{sub {mu}}{sup {mu}}>/m{sup 4}{yields}const{ne}0 at criticality limit, where M{sub TD} is the mass of TD and F{sub TD} the decay constant of TD. We thus conclude that at criticality limit the TD could become a ''true

  15. Conformational implications of asparagine-linked glycosylation.

    PubMed Central

    Imperiali, B; Rickert, K W

    1995-01-01

    The effects of cotranslational protein modification on the process of protein folding are poorly understood. Time-resolved fluorescence energy transfer has been used to assess the impact of glycosylation on the conformational dynamics of flexible oligopeptides. The peptide sequences examined are selected from glycoproteins of known three-dimensional structure. The energy transfer modulation associated with N-linked glycosylation is consistent with the glycopeptides sampling different conformational profiles in water. Results show that glycosylation causes the modified peptides to adopt a different ensemble of conformations, and for some peptides this change may lead to conformations that are more compact and better approximate the conformation of these peptides in the final folded protein. This result further implies that cotranslational glycosylation can trigger the timely formation of structural nucleation elements and thus assist in the complex process of protein folding. PMID:7816856

  16. Superintegrability of d-Dimensional Conformal Blocks.

    PubMed

    Isachenkov, Mikhail; Schomerus, Volker

    2016-08-12

    We observe that conformal blocks of scalar four-point functions in a d-dimensional conformal field theory can be mapped to eigenfunctions of a two-particle hyperbolic Calogero-Sutherland Hamiltonian. The latter describes two coupled Pöschl-Teller particles. Their interaction, whose strength depends smoothly on the dimension d, is known to be superintegrable. Our observation enables us to exploit the rich mathematical literature on Calogero-Sutherland models in deriving various results for conformal field theory. These include an explicit construction of conformal blocks in terms of Heckman-Opdam hypergeometric functions. We conclude with a short outlook, in particular, on the consequences of integrability for the theory of conformal blocks. PMID:27563949

  17. Conformational analysis of 2-substituted piperazines.

    PubMed

    Kallel, E Adam; Vangel, Colin; Elbaum, Daniel

    2016-07-01

    The unusual activity differences of carbon linked versus oxygen linked 2-substituted piperazines as α7 nicotinic acetylcholine receptor agonists led to a conformational study of several examples. The conformational preferences of which are absent from the literature. We report the first study and explanation of the conformational preference of 2-substiturted piperazines and show an example of how this preference controls binding in a pharmaceutically relevant case. In all cases the axial conformation for these 1-acyl and 1 aryl 2-substituted piperazines was found to be preferred. For the ether linked compounds, the axial conformation was found to be further stabilized by an intramolecular hydrogen bond. The axial orientation also places the basic and pyridyl nitrogens into a special orientation that closely mimics nicotine. Molecular modeling studies confirm that the R enantiomers of the compounds can bind to the α7 nicotinic acetylcholine receptor with the basic and pyridyl nitrogens colocalized with their counterparts in Epibatidine. PMID:27212066

  18. Vertex operator algebras and conformal field theory

    SciTech Connect

    Huang, Y.Z. )

    1992-04-20

    This paper discusses conformal field theory, an important physical theory, describing both two-dimensional critical phenomena in condensed matter physics and classical motions of strings in string theory. The study of conformal field theory will deepen the understanding of these theories and will help to understand string theory conceptually. Besides its importance in physics, the beautiful and rich mathematical structure of conformal field theory has interested many mathematicians. New relations between different branches of mathematics, such as representations of infinite-dimensional Lie algebras and Lie groups, Riemann surfaces and algebraic curves, the Monster sporadic group, modular functions and modular forms, elliptic genera and elliptic cohomology, Calabi-Yau manifolds, tensor categories, and knot theory, are revealed in the study of conformal field theory. It is therefore believed that the study of the mathematics involved in conformal field theory will ultimately lead to new mathematical structures which would be important to both mathematics and physics.

  19. Dolastatin 11 conformations, analogues and pharmacophore.

    PubMed

    Ali, Md Ahad; Bates, Robert B; Crane, Zackary D; Dicus, Christopher W; Gramme, Michelle R; Hamel, Ernest; Marcischak, Jacob; Martinez, David S; McClure, Kelly J; Nakkiew, Pichaya; Pettit, George R; Stessman, Chad C; Sufi, Bilal A; Yarick, Gayle V

    2005-07-01

    Twenty analogues of the natural antitumor agent dolastatin 11, including majusculamide C, were synthesized and tested for cytotoxicity against human cancer cells and stimulation of actin polymerization. Only analogues containing the 30-membered ring were active. Molecular modeling and NMR evidence showed the low-energy conformations. The amide bonds are all trans except for the one between the Tyr and Val units, which is cis. Since an analogue restricted to negative 2-3-4-5 angles stimulated actin polymerization but was inactive in cells, the binding conformation (most likely the lowest-energy conformation in water) has a negative 2-3-4-5 angle, whereas a conformation with a positive 2-3-4-5 angle (most likely the lowest energy conformation in chloroform) goes through cell walls. The highly active R alcohol from borohydride reduction of dolastatin 11 is a candidate for conversion to prodrugs. PMID:15878670

  20. 10. Exploring the Conformal Constraint Equations

    NASA Astrophysics Data System (ADS)

    Butscher, Adrian

    One method of studying the asymptotic structure of spacetime is to apply Penrose's conformal rescaling technique. In this setting, the rescaled Einstein equations for the metric and the conformal factor in the unphysical spacetime degenerate where the conformal factor vanishes, namely at the boundary representing null infinity. This problem can be avoided by means of a technique of H. Friedrich, which replaces the Einstein equations in the unphysical spacetime by an equivalent system of equations which is regular at the boundary. The initial value problem for these equations produces a system of constraint equations known as the conformal constraint equations. This work describes some of the properties of the conformal constraint equations and develops a perturbative method of generating solutions near Euclidean space under certain simplifying assumptions.