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Sample records for 4x5 copy negative

  1. 23. Photographic copy enlargement from a 4x5 copy negative of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photographic copy enlargement from a 4x5 copy negative of a drawing (Original drawing located on abandoned NASA site, currently owned by the City of Downey, Downey, Calfornia). JANUARY 1960 USAF PLANT 16 MASTER PLOT AND GRID PLAN. - NASA Industrial Plant, Missile Research Laboratory, 12214 Lakewood Boulevard, Downey, Los Angeles County, CA

  2. 22. Photographic copy enlargement from a 4x5 copy negative of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photographic copy enlargement from a 4x5 copy negative of a print. (Original print located on abandoned NASA site, currently owned by the City of Downey, Downey, California). 1954 USAF PLANT 16 AERIAL BUILDING 41 NORTH TO SOUTH. - NASA Industrial Plant, Missile Research Laboratory, 12214 Lakewood Boulevard, Downey, Los Angeles County, CA

  3. 15. Photographic copy englargement from a 4x5 copy negative (Original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photographic copy englargement from a 4x5 copy negative (Original drawing located on abandoned NASA site, currently owned by the City of Downey, Downey, California). 1980 BLDG 10, BLDG 42 FLOOR PLAN, NASA MARCH 15 1980. - NASA Industrial Plant, Maintenance Facility, 12214 Lakewood Boulevard, Downey, Los Angeles County, CA

  4. 9. Photographic copy enlargement from a 4x5 copy negative. (Original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photographic copy enlargement from a 4x5 copy negative. (Original drawing located on abandoned NASA site, currently owned by the City of Downey, Downey, California). 1976 BLDGS.25, 41 SITE PLAN. - NASA Industrial Plant, Storage Facility, 12214 Lakewood Boulevard, Downey, Los Angeles County, CA

  5. 14. Photographic copy englargement from a 4x5 copy negative (Original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photographic copy englargement from a 4x5 copy negative (Original photograph by original photographer located on abandoned NASA site, currently owned by the City of Downey, Downey, California). AERIAL PHOTOGRAPH 1935-1936 CONSOLIDATED VULTEE AIRCRAFT CORPORATION FROM WEST TO EAST - NASA Industrial Plant, Maintenance Facility, 12214 Lakewood Boulevard, Downey, Los Angeles County, CA

  6. 8. Photographic copy of photograph (from original 4 x 5 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photographic copy of photograph (from original 4 x 5 black and white print in the Army Port Contractors' 'Completion Report' at the Engineering Office, Oakland Army Base, California). Photograph taken May 13, 1942 by unknown photographer. BIRDS-EYE VIEW FROM THE SOUTH OF PRINTING PLANT (STOREHOUSE, BLDG. 85) AT CENTER TOP; STOREHOUSE (BLDG. 88) AT TOP RIGHT; GENERAL PURPOSE ADMINISTRATION BUILDING (BLDG. 90) AT CENTER. - Oakland Army Base, Maritime Street at West Grand Avenue, Oakland, Alameda County, CA

  7. 16. Photographic copy of photograph (from original 4 x 5 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photographic copy of photograph (from original 4 x 5 black and white print in the Army Port Contractors' 'Completion Report' at the Engineering Office, Oakland Army Base, California). Photograph taken prior to June 1942 by unknown photographer. SOUTHWEST BIRDS-EYE VIEW OF WAREHOUSES (BLDGS. 802-805). - Oakland Army Base, Warehouse Type, Tobruk Street, between Warehouse Road & Fifteenth Street, Oakland, Alameda County, CA

  8. 7. Photographic copy (reduced to 4 x 5 from 8 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy (reduced to 4 x 5 from 8 X 10 black and white paper reproduction in 1941 appraisal by E.E. Malloy at the Engineering Office, Oakland Army Base, California). Photograph taken between June 1940 and January 1941 by unknown photographer. PARTIAL SOUTH ELEVATION OF VEHICLE MAINTENANCE SHOP (BLDG. 99). - Oakland Army Base, Vehicle Maintenance Shop, Attu Street & Corregidor Avenue, Oakland, Alameda County, CA

  9. 11. Photographic copy of photograph (from original 4 x 5 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of photograph (from original 4 x 5 black and white print in the Army Port Contractors' 'Completion Report' at the Engineering Office, Oakland Army Base, California). Photograph taken January 31, 1942 by unknown photographer. EAST AND NORTH SIDES OBLIQUE VIEW OF EXCHANGE CAFETERIA (BLDG. 60). - Oakland Army Base, Private Exchange Cafeteria, Bataan Avenue & Attu Street, facing Post Headquarters Building, Oakland, Alameda County, CA

  10. 7. Photographic copy of photograph (from original 4 x 5 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of photograph (from original 4 x 5 black and white print in the Army Port Contractors' 'Completion Report' at the Engineering Office, Oakland Army Base, California). Photograph taken January 28, 1942 by unknown photographer. AT CENTER RIGHT, SOUTH AND EAST SIDES OBLIQUE VIEW OF POST HEADQUARTERS BUILDING (ADMINISTRATION BUILDING, BLDG. 1) TAKEN FROM EAST SIDE OF MARITIME STREET. - Oakland Army Base, Maritime Street at West Grand Avenue, Oakland, Alameda County, CA

  11. 6. Photographic copy of photograph (from original 4 x 5 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photographic copy of photograph (from original 4 x 5 black and white print in the Army Port Contractors' 'Completion Report' at the Engineering Office, Oakland Army Base, California). Photograph taken April 6, 1942 by unknown photographer. SOUTH AND EAST SIDES OBLIQUE VIEW OF PRIVATE VEHICLE INSPECTION BUILDING (VEHICLE SHED, BLDG. 4). - Oakland Army Base, Private Vehicle Inspection Building, Africa Street & Bataan Avenue, Oakland, Alameda County, CA

  12. 9. (5 X 7 enlargement from 4 X 5 negative) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. (5 X 7 enlargement from 4 X 5 negative) FIRST FLOOR, WINDOW MOLDING ON SOUTH WALL LOOKING SOUTH - Sites Homestead, Monongahela National Forest (Tract 390) East of Route 28, Seneca Rocks, Pendleton County, WV

  13. Credit WCT. Original 4" x 5" black and white negative ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Original 4" x 5" black and white negative is housed in the JPL Archives, Pasadena, California. This view shows the original furnace for burning scrap propellant, the surrounding incinerator pit, and the earth mound personnel shield (JPL negative no. 381-2737, 11 February 1963) - Jet Propulsion Laboratory Edwards Facility, Incinerator, Edwards Air Force Base, Boron, Kern County, CA

  14. 9. 8' X 10' Enlargement from 4' x 5' negative ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. 8' X 10' Enlargement from 4' x 5' negative Kevin Kriesel-Coons, Photographer PUMPS AFTER REMOVAL FROM PUMPHOUSE BEFORE EXCAVATION OF POND AREA IN 1989. PHOTOGRAPHED LYING ON GROUND NEAR CROSSCUT STEAM PLANT BUILDING. - Crosscut Steam Plant, Indian Bend Pond & Pump Ditch, North side Salt River near Mill Avenue & Washington Street, Tempe, Maricopa County, AZ

  15. 16. (4'X5' image enlarged from 2 1/4' negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. (4'X5' image enlarged from 2 1/4' negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE). DETAIL OF TURN-SPAN MECHANISM. - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  16. 15. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) PIVOT PIER - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  17. 13. (4'X5' image enlarged from 2 1/4' negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. (4'X5' image enlarged from 2 1/4' negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) NORTH SIDE ELEVATION. - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  18. 17. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) APPROACH SPAN FENDER - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  19. 12. (4'X5' image enlarged from 2 1/4' negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. (4'X5' image enlarged from 2 1/4' negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) SOUTH SIDE ELEVATION. - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  20. 14. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) TURN-SPAN AND LOCKING MECHANISM - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  1. 16. Photocopy of drawing enlarged from a 4x5 negative (from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of drawing enlarged from a 4x5 negative (from Cultural Resources plan files, Gateway National Recreation Area, New Jersey) U.S. Army Corps of Engineers, Designers, 1909 PLAN OF DRAINAGE AND ELECTRICAL SYSTEM OF BATTERY - Fort Hancock, Battery George Arrowsmith, Southwest edge of Sandy Point extending to Horseshoe Cove, Fort Hancock, Monmouth County, NJ

  2. 19. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE). NAVIGATIONAL LIGHT LOCATED ON TOP OF FENDER - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  3. Credit WCT. Original 4"x5" black and white negative is housed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Original 4"x5" black and white negative is housed in the JPL Archives, Pasadena, California. This view shows the underfloor ductwork of Building E-46 during construction. The ductwork conducts hot or cold air to maintain required temperatures in the curing chamber (JPL negative no. 381-2569, 12 December 1962) - Jet Propulsion Laboratory Edwards Facility, Solid Propellant Conditioning Building, Edwards Air Force Base, Boron, Kern County, CA

  4. 3. Credit WCT. Original 4"x5" black and white negative is ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit WCT. Original 4"x5" black and white negative is housed in the JPL Archives, Pasadena, California. This view of the vibrator shows a large mounted ATS (Advanced Technology Satellite) motor. Accelerometer instrumentation has been added. JPL caption reads "C-210E Vibration Exciter ATS Accelerometer Installation on Q4TX AXIS" (JPL negative no. 384-5848B, 31 March 1966). - Jet Propulsion Laboratory Edwards Facility, Test Stand G, Edwards Air Force Base, Boron, Kern County, CA

  5. 20. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE). DETAIL OF FENDER SYSTEM FOR TURN-SPAN PIVOT PIER. OPERATOR'S HOUSE LOCATED ON UPPER SECTION OF TRUSS - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  6. 18. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) APPROACH SPAN FENDER. DOLPHIN LOCATED AT RIGHT. NAVIGATIONAL LIGHT LOCATED ON TOP OF FENDER - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

  7. Credit WCT. Original 4"x5" black and white negative is housed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Original 4"x5" black and white negative is housed in the JPL Archives, Pasadena, California. This image shows the tumble dryer in place as building construction neared completion. The mezzanine railings have not been installed. The scattered debris on the floor and stairs would not be allowed during dryer operation. Compare this view with CA-163-Q-2 and note that the stairs in this 1963 view were moved later; the screen wall was also removed. The reasons for these alterations were not determined (JPL negative no. 381-2831, 18 March 1963) - Jet Propulsion Laboratory Edwards Facility, Oxidizer Dryer Building, Edwards Air Force Base, Boron, Kern County, CA

  8. Credit WCT. Original 4" x 5" black and white print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Original 4" x 5" black and white print housed in the JPL Archives, Pasadena, California. This view displays the west elevation of the mixer building and barricades. The slide from the second floor balcony (missing in 1995) provided rapid emergency evacuation for personnel in case of fire or other imminent danger. JPL negative 384-10506, 7 July 1964 - Jet Propulsion Laboratory Edwards Facility, Mixer, Edwards Air Force Base, Boron, Kern County, CA

  9. 4. Credit JPL. Original 4" x 5" black and white ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Credit JPL. Original 4" x 5" black and white negative housed in the JPL Archives, Pasadena, California. This interior view displays the machine shop in the Administration/Shops Building (the compass angle of the view is undetermined). Looking clockwise from the lower left, the machine tools in view are a power hacksaw, a heat-treatment oven (with white gloves on top), a large hydraulic press with a tool grinder at its immediate right; along the wall in the back of the view are various unidentified machine tool attachments and a vertical milling machine. In the background, a machinist is operating a radial drilling machine, to the right of which is a small drill press. To the lower right, another machinist is operating a Pratt & Whitney engine lathe; behind the operator stand a workbench and vertical bandsaw (JPL negative no. 384-10939, 29 July 1975). - Jet Propulsion Laboratory Edwards Facility, Administration & Shops Building, Edwards Air Force Base, Boron, Kern County, CA

  10. 14. Photocopy of photograph (4 x 5 inch reduction of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of photograph (4 x 5 inch reduction of 1939 3-5/8 x 6 inch print by R. Fromme; in Recreation files, Supervisor's Office, Mt. Baker-Snoqualmie National Forest) ENTRANCE TO GLACIER RANGER STATION, FROM WEST. GARAGE AND STORAGE BUILDING IN LEFT BACKGROUND. - Glacier Ranger Station, Washington State Route 542, Glacier, Whatcom County, WA

  11. 23. Photocopy of photograph (4 x 5 inch enlargement of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photocopy of photograph (4 x 5 inch enlargement of 1940 3-1/4 x 4-1/4 inch print by R. Nevan McCullough; in Cultural Resource files, Supervisor's Office, Mt. Baker-Snoqualmie National Forest) SOUTH FRONT - Suntop Lookout, Forest Road 510, Mt. Baker-Snoqualmie National Forest, Greenwater, Pierce County, WA

  12. 3. Photographic copy of photograph (ca. 1955, original negative found ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photographic copy of photograph (ca. 1955, original negative found in Beierle Barn, now on file at New Denver International Airport Office, Stapleton International Ariport, Denver, CO). VIEW OF RESIDENCE AND FARM, LOOKING NORTHEAST. - Beierle Farm, Hudson Road & Ninety-Sixth Avenue, Denver, Denver County, CO

  13. Copy Photograph (original negative in possession of LSA Associates, Irvine, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Copy Photograph (original negative in possession of LSA Associates, Irvine, California) Rebecca Conard, Photographer, January 1989 STORAGE SHED, WEST (FRONT), LOOKING EAST - Irvine Ranch Agricultural Headquarters, Boyd Tenant House, Southeast of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  14. Copy Photograph (original negative in possession of LSA Associates, Irvine, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Copy Photograph (original negative in possession of LSA Associates, Irvine, California) Beth Padon, Photographer, 1985 MACHINE AND CHEMICAL STORAGE BUILDING, NORTH (FRONT), LOOKING SOUTH - Irvine Ranch Agricultural Headquarters, Boyd Tenant House, Southeast of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  15. Copy Photograph (original negative in possession of LSA Associates, Irvine, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Copy Photograph (original negative in possession of LSA Associates, Irvine, California) Beth Padon, Photographer, 1985 BOYD FARMSTEAD, LOOKING SOUTHEAST, WATER TANK, HOUSE, GARAGE - Irvine Ranch Agricultural Headquarters, Boyd Tenant House, Southeast of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  16. Copy Photograph (original negative in possession of LSA Associates, Irvine, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Copy Photograph (original negative in possession of LSA Associates, Irvine, California) Beth Padon, Photographer, 1985 BOYD FARMSTEAD IN RELATION TO I-5, LOOKING SOUTHWEST - Irvine Ranch Agricultural Headquarters, Boyd Tenant House, Southeast of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  17. Copy Photograph (original negative in possession of LSA Associates, Irvine, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Copy Photograph (original negative in possession of LSA Associates, Irvine, California) Beth Padon, Photographer, 1985 BOYD FARMSTEAD, LOOKING NORTHEAST, GARAGE, HOUSE, RAILROAD CAR PRESENT IN 1985 BUT REMOVED BY JANUARY 1989 - Irvine Ranch Agricultural Headquarters, Boyd Tenant House, Southeast of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  18. 5. Photographic copy of a photograph taken from pasteup negatives ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photographic copy of a photograph taken from paste-up negatives for U.S. Army Corps of Engineers document GF-500-MCP, entitled "Grand Forks Site RLS Army Operating Drawings, Master Composite Photographs for SAFEGUARD TSE Systems and Equipment," Page 9, dated 1 September 1974 (original document and negatives in possession of U.S. Army Corps of Engineers, Huntsville, AL). Photographer unknown. View of pneumatic control panel regulating entrance to waiting room #116. The panel activated the pneumatic cylinder for opening and closing of blast doors #116 and #118. A rotary air motor actuated locking and unlocking of the doors. - Stanley R. Mickelsen Safeguard Complex, Remote Launch Operations Building, Near Service Road exit from Patrol Road, Nekoma, Cavalier County, ND

  19. 4. Photographic copy of a photograph taken from pasteup negatives ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photographic copy of a photograph taken from paste-up negatives for U.S. Army Corps of Engineers document GF-500-MCP, entitled "Grand Forks Site RLS Army Operating Drawings, Master Composite Photographs for SAFEGUARD TSE Systems and Equipment," Page 9, dated 1 September 1974 (original document and negatives in possession of U.S. Army Corps of Engineers, Huntsville, AL). Photographer unknown. View of remote launch operations building exterior (southwest corner), prior to earth mounding. A,B,C, and D are heat exchangers HX-1102B, HX-1102A, HX-1101B, and HX-1101 A, respectively. The heat exchangers transferred heat from the cooling water to the outside air during the normal operating mode. On the far right is the air exhaust shaft - Stanley R. Mickelsen Safeguard Complex, Remote Launch Operations Building, Near Service Road exit from Patrol Road, Nekoma, Cavalier County, ND

  20. 6. Photographic copy of a photograph taken from pasteup negatives ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photographic copy of a photograph taken from paste-up negatives for U.S. Army Corps of Engineers document GF-500-MCP, entitled "Grand Forks Site RLS Army Operating Drawings, Master Composite Photographs for SAFEGUARD TSE Systems and Equipment," Page 9, dated 1 September 1974 (original document and negatives in possession of U.S. Army Corps of Engineers, Huntsville, AL). Photographer unknown. View of remote launch operations building, power generation room #124, showing no-break units NB-1002 (A) and NB-1001 (B). This equipment consisted of a 150 horsepower, d.c. operational motor which drove, on each end of the extended shaft, a 70 kw generator and a 30 kw generator unit. It was designed to provide continuous power service for launch equipment. In particular, the photo is an excellent representation of the shock isolation scheme, as evidenced by the supporting air springs and equipment platform - Stanley R. Mickelsen Safeguard Complex, Remote Launch Operations Building, Near Service Road exit from Patrol Road, Nekoma, Cavalier County, ND

  1. 36 CFR 1258.8 - Who pays to have a copy negative made?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Who pays to have a copy negative made? 1258.8 Section 1258.8 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE FEES § 1258.8 Who pays to have a copy negative made? Requests...

  2. 4. Photographic copy of map. San Carlos Irrigation Project, Gila ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photographic copy of map. San Carlos Irrigation Project, Gila River Indian Reservation, Pinal County, Arizona. Department of the Interior. Office of Indian Affairs. 1940. (Source: SCIP Office, Coolidge, AZ) Photograph is an 8'x10' enlargement from a 4'x5' negative. - San Carlos Irrigation Project, Lands North & South of Gila River, Coolidge, Pinal County, AZ

  3. 2. Photographic copy of photograph, undated, in possession of Arizona ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photographic copy of photograph, undated, in possession of Arizona Historical Society. Photograph #793. Photographer unknown. BUILDING FLORENCE RESERVOIR (PRESUMABLY PICACHO RESERVOIR) Photograph is an 8'x10' enlargement from a 4'x5' negative. - San Carlos Irrigation Project, Picacho Resevoir, South of Gila River, Coolidge, Pinal County, AZ

  4. High EGFR gene copy number predicts poor outcome in triple-negative breast cancer.

    PubMed

    Park, Heae Surng; Jang, Min Hye; Kim, Eun Joo; Kim, Hyun Jeong; Lee, Hee Jin; Kim, Yu Jung; Kim, Jee Hyun; Kang, Eunyoung; Kim, Sung-Won; Kim, In Ah; Park, So Yeon

    2014-09-01

    Epidermal growth factor receptor (EGFR) is frequently overexpressed in triple-negative breast cancer and is emerging as a therapeutic target. EGFR gene copy number alteration and mutation are highly variable and scientists have been challenged to define their prognostic significance in triple-negative breast cancer. We examined EGFR protein expression, EGFR gene copy number alteration and mutation of exon 18 to 21 in 151 cases of triple-negative breast cancer and correlated these findings with clinical outcomes. In addition, intratumoral agreement of EGFR protein overexpression and gene copy number alteration was evaluated. EGFR overexpression was found in 97 of 151 cases (64%) and high EGFR gene copy number was detected in 50 cases (33%), including 3 gene amplification (2%) and 47 high polysomy (31%). Five EGFR mutations were detected in 4 of 151 cases (3%) and included G719A in exon 18 (n=1), V786M in exon 20 (n=1), and L858R in exon 21 (n=3). One case had two mutations (G719A and L858R). High EGFR copy number, but not EGFR mutation, correlated with EGFR protein overexpression. Intratumoral heterogeneity of EGFR protein overexpression and EGFR copy number alteration was not significant. In survival analyses, high EGFR copy number was found to be an independent prognostic factor for poor disease-free survival in patients with triple-negative breast cancer. Our findings showed that EGFR mutation was a rare event, but high EGFR copy number was relatively frequent and correlated with EGFR overexpression in triple-negative breast cancer. Moreover, high EGFR copy number was associated with poor clinical outcome in triple-negative breast cancer, suggesting that evaluation of EGFR copy number may be useful for predicting outcomes in patients with triple-negative breast cancer and for selecting patients for anti-EGFR-targeted therapy.

  5. 32. PORT PROFILE OF THE ALABAMA. Uncopyrighted 31/4'x5'photograph taken by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. PORT PROFILE OF THE ALABAMA. Uncopyrighted 3-1/4'x5'photograph taken by Thigpen Photography, c. 1965. Written on back of photo: 'This is what the vessel looked like when I bought her in 1966 R.S. Douglas.' Also, stamped on back is: Thigpen Photography 1442 So. Beltline Highway Mobile, Alabama 46609 to reorder specify no. M7062-1 - Pilot Schooner "Alabama", Moored in harbor at Vineyard Haven, Vineyard Haven, Dukes County, MA

  6. Punctuated Copy Number Evolution and Clonal Stasis in Triple-Negative Breast Cancer

    PubMed Central

    Gao, Ruli; Davis, Alexander; McDonald, Thomas O.; Sei, Emi; Shi, Xiuqing; Wang, Yong; Tsai, Pei-Ching; Casasent, Anna; Waters, Jill; Zhang, Hong; Meric-Bernstam, Funda; Michor, Franziska; Navin, Nicholas E.

    2016-01-01

    Aneuploidy is a hallmark of breast cancer; however, our knowledge of how these complex genomic rearrangements evolve during tumorigenesis is limited. In this study we developed a highly multiplexed single-nucleus-sequencing method to investigate copy number evolution in triple-negative breast cancer patients. We sequenced 1000 single cells from 12 patients and identified 1–3 major clonal subpopulations in each tumor that shared a common evolutionary lineage. We also identified a minor subpopulation of non-clonal cells that were classified as: 1) metastable, 2) pseudo-diploid, or 3) chromazemic. Phylogenetic analysis and mathematical modeling suggest that these data are unlikely to be explained by the gradual accumulation of copy number events over time. In contrast, our data challenge the paradigm of gradual evolution, showing that the majority of copy number aberrations are acquired at the earliest stages of tumor evolution, in short punctuated bursts, followed by stable clonal expansions that form the tumor mass. PMID:27526321

  7. 2. Photographic copy of map. Gila River Project, General Map ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photographic copy of map. Gila River Project, General Map Showing Progress for the Fiscal Year 1927. (Source: U.S. Department of Interior. Office of Indian Affairs. Indian Irrigation Service. Annual Report, Fiscal Year 1927. Vol. I, Narrative and Photographs, District #4, RG 75, Entry 655, Box 29, National Archives, Washington, DC.) Photograph is an 8'x10' enlargement from a 4'x5' negative. - San Carlos Irrigation Project, Lands North & South of Gila River, Coolidge, Pinal County, AZ

  8. 1. Copy photo of context view taken in 1917 looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Copy photo of context view taken in 1917 looking east along Farragut Avenue, then called Main Street, showing construction of double tracking. On right is Building 78 with original smoke stack. Building 59 is visible as third building from left. This photograph was taken from a hill that was later cut away in order to expand the shipyard. See photo for original caption. HABS negative is a 4x5' copy negative made from a print in the collection of the Photographic Branch, Puget Sound Naval Shipyard, Bremerton, WA. Photographer unknown. - Puget Sound Naval Shipyard, Administration Building, Farragut Avenue, Bremerton, Kitsap County, WA

  9. Discovering Recurrent Copy Number Aberrations in Complex Patterns via Non-Negative Sparse Singular Value Decomposition.

    PubMed

    Xi, Jianing; Li, Ao

    2016-01-01

    Recurrent copy number aberrations (RCNAs) in multiple cancer samples are strongly associated with tumorigenesis, and RCNA discovery is helpful to cancer research and treatment. Despite the emergence of numerous RCNA discovering methods, most of them are unable to detect RCNAs in complex patterns that are influenced by complicating factors including aberration in partial samples, co-existing of gains and losses and normal-like tumor samples. Here, we propose a novel computational method, called non-negative sparse singular value decomposition (NN-SSVD), to address the RCNA discovering problem in complex patterns. In NN-SSVD, the measurement of RCNA is based on the aberration frequency in a part of samples rather than all samples, which can circumvent the complexity of different RCNA patterns. We evaluate NN-SSVD on synthetic dataset by comparison on detection scores and Receiver Operating Characteristics curves, and the results show that NN-SSVD outperforms existing methods in RCNA discovery and demonstrate more robustness to RCNA complicating factors. Applying our approach on a breast cancer dataset, we successfully identify a number of genomic regions that are strongly correlated with previous studies, which harbor a bunch of known breast cancer associated genes.

  10. Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival.

    PubMed

    Chen, Chu; Zhang, Yuzheng; Loomis, Melissa M; Upton, Melissa P; Lohavanichbutr, Pawadee; Houck, John R; Doody, David R; Mendez, Eduardo; Futran, Neal; Schwartz, Stephen M; Wang, Pei

    2015-01-01

    Oral squamous cell cancer of the oral cavity and oropharynx (OSCC) is associated with high case-fatality. For reasons that are largely unknown, patients with the same clinical and pathologic staging have heterogeneous response to treatment and different probability of recurrence and survival, with patients with Human Papillomavirus (HPV)-positive oropharyngeal tumors having the most favorable survival. To gain insight into the complexity of OSCC and to identify potential chromosomal changes that may be associated with OSCC mortality, we used Affymtrix 6.0 SNP arrays to examine paired DNA from peripheral blood and tumor cell populations isolated by laser capture microdissection to assess genome-wide loss of heterozygosity (LOH) and DNA copy number aberration (CNA) and their associations with risk factors, tumor characteristics, and oral cancer-specific mortality among 75 patients with HPV-negative OSCC. We found a highly heterogeneous and complex genomic landscape of HPV-negative tumors, and identified regions in 4q, 8p, 9p and 11q that seem to play an important role in oral cancer biology and survival from this disease. If confirmed, these findings could assist in designing personalized treatment or in the creation of models to predict survival in patients with HPV-negative OSCC.

  11. PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas

    PubMed Central

    Nakae, Shunsuke; Sasaki, Hikaru; Hayashi, Saeko; Hattori, Natsuki; Kumon, Masanobu; Nishiyama, Yuya; Adachi, Kazuhide; Nagahisa, Shinya; Hayashi, Takuro; Inamasu, Joji; Abe, Masato; Hasegawa, Mitsuhiro; Hirose, Yuichi

    2015-01-01

    Genetic subgrouping of gliomas has been emphasized recently, particularly after the finding of isocitrate dehydrogenase 1 (IDH1) mutations. In a previous study, we investigated whole-chromosome copy number aberrations (CNAs) of gliomas and have described genetic subgrouping based on CNAs and IDH1 mutations. Subsequently, we classified gliomas using simple polymerase chain reaction (PCR)-based methods to improve the availability of genetic subgrouping. We selected IDH1/2 and TP53 as markers and analyzed 237 adult supratentorial gliomas using Sanger sequencing. Using these markers, we classified gliomas into three subgroups that were strongly associated with patient prognoses. These included IDH mutant gliomas without TP53 mutations, IDH mutant gliomas with TP53 mutations, and IDH wild-type gliomas. IDH mutant gliomas without TP53 mutations, which mostly corresponded to gliomas carrying 1p19q co-deletions, showed lower recurrence rates than the other 2 groups. In the other high-recurrence groups, the median progression-free survival (PFS) and overall survival (OS) of patients with IDH mutant gliomas with TP53 mutations were significantly longer than those of patients with IDH wild-type gliomas. Notably, most IDH mutant gliomas with TP53 mutations had at least one of the CNAs +7q, +8q, −9p, and −11p. Moreover, IDH mutant gliomas with at least one of these CNAs had a significantly worse prognosis than did other IDH mutant gliomas. PCR-based mutation analyses of IDH and TP53 were sufficient for simple genetic diagnosis of glioma that were strongly associated with prognosis of patients and enabled us to detect negative CNAs in IDH mutant gliomas. PMID:26558387

  12. PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas.

    PubMed

    Nakae, Shunsuke; Sasaki, Hikaru; Hayashi, Saeko; Hattori, Natsuki; Kumon, Masanobu; Nishiyama, Yuya; Adachi, Kazuhide; Nagahisa, Shinya; Hayashi, Takuro; Inamasu, Joji; Abe, Masato; Hasegawa, Mitsuhiro; Hirose, Yuichi

    2015-01-01

    Genetic subgrouping of gliomas has been emphasized recently, particularly after the finding of isocitrate dehydrogenase 1 (IDH1) mutations. In a previous study, we investigated whole-chromosome copy number aberrations (CNAs) of gliomas and have described genetic subgrouping based on CNAs and IDH1 mutations. Subsequently, we classified gliomas using simple polymerase chain reaction (PCR)-based methods to improve the availability of genetic subgrouping. We selected IDH1/2 and TP53 as markers and analyzed 237 adult supratentorial gliomas using Sanger sequencing. Using these markers, we classified gliomas into three subgroups that were strongly associated with patient prognoses. These included IDH mutant gliomas without TP53 mutations, IDH mutant gliomas with TP53 mutations, and IDH wild-type gliomas. IDH mutant gliomas without TP53 mutations, which mostly corresponded to gliomas carrying 1p19q co-deletions, showed lower recurrence rates than the other 2 groups. In the other high-recurrence groups, the median progression-free survival (PFS) and overall survival (OS) of patients with IDH mutant gliomas with TP53 mutations were significantly longer than those of patients with IDH wild-type gliomas. Notably, most IDH mutant gliomas with TP53 mutations had at least one of the CNAs +7q, +8q, -9p, and -11p. Moreover, IDH mutant gliomas with at least one of these CNAs had a significantly worse prognosis than did other IDH mutant gliomas. PCR-based mutation analyses of IDH and TP53 were sufficient for simple genetic diagnosis of glioma that were strongly associated with prognosis of patients and enabled us to detect negative CNAs in IDH mutant gliomas.

  13. Chopping Copy.

    ERIC Educational Resources Information Center

    Bush, Don

    1994-01-01

    Discusses ways an editor can cut out words to help the reader understand quickly. Discusses dead wood, redundancy, redundancy in thought, smothered verbs, false precision, editing and academia, and making copy smoother. (SR)

  14. bla(KPC) RNA expression correlates with two transcriptional start sites but not always with gene copy number in four genera of Gram-negative pathogens.

    PubMed

    Roth, Amanda L; Kurpiel, Philip M; Lister, Philip D; Hanson, Nancy D

    2011-08-01

    Klebsiella pneumoniae carbapenemase (KPC)-producing organisms are therapeutically and diagnostically challenging. It is possible that bla(KPC) gene expression plays a role in the variability observed in clinical susceptibility testing. bla(KPC) transformants together with 10 clinical isolates representing four genera were evaluated for bla(KPC) copy number and gene expression and correlated with β-lactam MIC data. The data suggest that mechanisms other than gene copy number and expression of bla(KPC) contribute to variability in susceptibility when testing KPC-producing isolates.

  15. Construction of mobilizable mini-Tn7 vectors for bioluminescent detection of gram-negative bacteria and single-copy promoter lux reporter analysis.

    PubMed

    Damron, F Heath; McKenney, Elizabeth S; Barbier, Mariette; Liechti, George W; Schweizer, Herbert P; Goldberg, Joanna B

    2013-07-01

    We describe the construction of mini-Tn7-based broad-host-range vectors encoding lux genes as bioluminescent reporters. These constructs can be mobilized into the desired host(s) by conjugation for chromosomal mini-Tn7-lux integration and are useful for localization of bacteria during infections or for characterizing regulation of promoters of interest in Gram-negative bacteria.

  16. Identification of copy-number abnormalities and inactivating mutations in two negative regulators of NF-kB signaling pathways in Waldenström’s Macroglobulinemia

    PubMed Central

    Braggio, Esteban; Keats, Jonathan J; Leleu, Xavier; Van Wier, Scott; Jimenez-Zepeda, Victor H; Valdez, Riccardo; Schop, Roelandt FJ; Price-Troska, Tammy; Henderson, Kimberly; Sacco, Antonio; Azab, Feda; Greipp, Philip; Gertz, Morie; Hayman, Suzanne; Rajkumar, S Vincent; Carpten, John; Chesi, Marta; Barrett, Michael; Stewart, A Keith; Dogan, Ahmet; Bergsagel, P Leif; Ghobrial, Irene M; Fonseca, Rafael

    2009-01-01

    Waldenström’s macroglobulinemia (WM) is a distinct clinico-biological entity defined as a B-cell neoplasm characterized by a lymphoplasmacytic infiltrate in the bone marrow (BM) and immunoglobulin M paraprotein production. Cytogenetic analyses were historically limited by the difficulty in obtaining tumor metaphases and the genetic basis of the disease remains poorly defined. Here we performed a comprehensive analysis in 42 WM patients by using high-resolution, array-based comparative genomic hybridization approach to unravel the genetic mechanisms associated with WM pathogenesis. Overall, 83% of patients have chromosomal abnormalities, with a median of three abnormalities per patient. Gain of 6p was the second most common abnormality (17%) and its presence was always concomitant with 6q loss. A minimal deleted region, including MIRN15A and MIRN16-1, was delineated on 13q14 in 10% of patients. Of interest, we reported biallelic deletions and/or inactivating mutations with uniparental disomy in TRAF3 and TNFAIP3, two negative regulators of the NF-kB signaling pathway. Furthermore, we confirmed the association between TRAF3 inactivation and increased transcriptional activity of NF-kB target genes. Mutational activation of the NF-kB pathway, which is normally activated by ligand-receptor interactions within the BM microenvironment, highlights its biologic importance, and suggests a therapeutic role for inhibitors of NF-kB pathway activation in the treatment of Waldenström’s macroglobulinemia. PMID:19351844

  17. Breaking and Entering: Copying and Copy Protection.

    ERIC Educational Resources Information Center

    Westlake, Wayne; And Others

    1985-01-01

    Describes several commercially-available computer programs which allow users to make copies of "protected" software. Current costs, program features, and ordering information are provided for these "encryption" programs. Also describes a monthly journal (The HARDCORE Computist) which focuses on unlocking copy-protected…

  18. Copy-left and Copy-right

    NASA Astrophysics Data System (ADS)

    VanderPlas, Jacob

    2015-01-01

    Any discussion of open licensing almost invariably devolves into a debate between copy-left licenses and permissive licenses, both sides defending their views with a nearly religious fervor. Copy-left licenses, typified by the GPL family of licenses, require all derived products to maintain the open, GPL license. Permissive licenses, typified by the BSD family of licenses, do not impose such requirements. I'll briefly explore the common arguments put forth in favor of either approach, and discuss some concrete examples of where these approaches have helped or hindered the software packages that used them.

  19. Copy Machine Art.

    ERIC Educational Resources Information Center

    Sommer, Jean

    1984-01-01

    Images created with copy machines make children feel successful, as their work acquires the authority of being printed. Students can learn advanced processes like electrostatic image-making and can get involved in projects like making collages. They acquire an appreciation of design and of two-dimensional composition. (CS)

  20. Rare Copy Number Variants

    PubMed Central

    Grozeva, Detelina; Kirov, George; Ivanov, Dobril; Jones, Ian R.; Jones, Lisa; Green, Elaine K.; St Clair, David M.; Young, Allan H.; Ferrier, Nicol; Farmer, Anne E.; McGuffin, Peter; Holmans, Peter A.; Owen, Michael J.; O’Donovan, Michael C.; Craddock, Nick

    2015-01-01

    Context Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including neuropsychiatric disorders such as schizophrenia and autism. The possible involvement of copy number variants (CNVs) in bipolar disorder has received little attention to date. Objectives To determine whether large (>100 000 base pairs) and rare (found in <1% of the population) CNVs are associated with susceptibility to bipolar disorder and to compare with findings in schizophrenia. Design A genome-wide survey of large, rare CNVs in a case-control sample using a high-density microarray. Setting The Wellcome Trust Case Control Consortium. Participants There were 1697 cases of bipolar disorder and 2806 nonpsychiatric controls. All participants were white UK residents. Main Outcome Measures Overall load of CNVs and presence of rare CNVs. Results The burden of CNVs in bipolar disorder was not increased compared with controls and was significantly less than in schizophrenia cases. The CNVs previously implicated in the etiology of schizophrenia were not more common in cases with bipolar disorder. Conclusions Schizophrenia and bipolar disorder differ with respect to CNV burden in general and association with specific CNVs in particular. Our data are consistent with the possibility that possession of large, rare deletions may modify the phenotype in those at risk of psychosis: those possessing such events are more likely to be diagnosed as having schizophrenia, and those without them are more likely to be diagnosed as having bipolar disorder. PMID:20368508

  1. 11. Photographic copy of copy of Twin Lakes Outlet Works ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of copy of Twin Lakes Outlet Works construction drawing dated January 15, 1951. Drawn by W.A. Doe for the Twin Lakes Reservoir and Canal Co. (copy in possession of Bureau of Reclamation, location of original unknown) 'AS CONSTRUCTED' PLANS OF 1949-1950, REHABILITATION OF TWIN LAKES RESERVOIR OUTLET WORKS, DETAILS OF UPSTREAM WING WALLS. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

  2. 12. Photographic copy of copy of Twin Lakes Outlet Works ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photographic copy of copy of Twin Lakes Outlet Works construction drawing dated January 15, 1951. Drawn by W.A. Doe for the Twin Lakes Reservoir and Canal Co. (copy in possession of Bureau of Reclamation, location of original unknown) 'AS CONSTRUCTED' PLANS OF 1949-50, REHABILITATION OF TWIN LAKES RESERVOIR OUTLET WORKS, DETAILS OF DISCHARGE BASIN. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

  3. Photocopy of copy of 1922 map, revised in 1936. Copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of copy of 1922 map, revised in 1936. Copy in the Fitzsimons Army Medical Center Directorate of Public Works, building 118. - Fitzsimons General Hospital, Bounded by East Colfax to south, Peoria Street to west, Denver City/County & Adams County Line to north, & U.S. Route 255 to east, Aurora, Adams County, CO

  4. 10. Photographic copy of copy of original construction drawing, dated ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photographic copy of copy of original construction drawing, dated 1899?. Original in possession of Twin Lakes Reservoir and Canal Company, Ordway, Colorado. PLAN OF DAM AND HEAD GATES FOR THE TWIN LAKES RESERVOIR. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

  5. Mechanisms of COPI vesicle formation

    PubMed Central

    Hsu, Victor W.; Yang, Jia-Shu

    2009-01-01

    Coat Protein I (COPI) is one of the most intensely investigated coat complexes. Numerous studies have contributed to a general understanding of how coat proteins act to initiate intracellular vesicular transport. This review highlights key recent findings that have shaped our current understanding of how COPI vesicles are formed. PMID:19854177

  6. Counting copy number and calories.

    PubMed

    White, Stefan

    2015-08-01

    Copy number variation (CNV) at several genomic loci has been associated with different human traits and diseases, but in many cases the findings could not be replicated. A new study provides insights into the degree of variation present at the amylase locus and calls into question a previous association between amylase copy number and body mass index.

  7. 10. Photographic copy of original construction drawing, sheet no. 1 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photographic copy of original construction drawing, sheet no. 1 of 21, dated November 1, 1940, taken from a 11 x 17 print of a 2 x 2 negative in the possession of the Utah Department of Transportation, Salt Lake City, Utah. SITE PLAN - Huntington Creek Bridge, Spanning Huntington Creek at State Route 10, Huntington, Emery County, UT

  8. 14. Photographic copy of original construction drawing, sheet no. 14 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photographic copy of original construction drawing, sheet no. 14 of 21, dated November 1, 1940, taken from a 11 x 17 print of a 2 x 2 negative in the possession of the Utah Department of Transportation, Salt City Lake, Utah. ELEVATIONS AND SECTION OF PIER #2 - Huntington Creek Bridge, Spanning Huntington Creek at State Route 10, Huntington, Emery County, UT

  9. 11. Photographic copy of original construction drawing, sheet no. 2 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of original construction drawing, sheet no. 2 of 21, dated November 1, 1940, taken from a 11 x 17 print of a 2 x 2 negative in the possession of the Utah Department of Transportation, Salt Lake City, Utah. PLAN AND ELEVATION - Huntington Creek Bridge, Spanning Huntington Creek at State Route 10, Huntington, Emery County, UT

  10. 12. Photographic copy of original construction drawing, sheet no. 3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photographic copy of original construction drawing, sheet no. 3 of 21, dated November 1, 1940, taken from a 11 x 17 print of a 2 x 2 negative in the possession of the Utah Department of Transportation, Salt Lake City, Utah. SECTION AT PIER #1, DETAILS, AND SECTIONS - Huntington Creek Bridge, Spanning Huntington Creek at State Route 10, Huntington, Emery County, UT

  11. 15. Photographic copy of original construction drawing, sheet no. 17 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photographic copy of original construction drawing, sheet no. 17 of 21, dated November 1, 1940, taken from a 11 x 17 print of a 2 x 2 negative in the possession of the Utah Department of Transportation, Salt Lake City, Utah. MISC. SECTIONS AND DETAILS - Huntington Creek Bridge, Spanning Huntington Creek at State Route 10, Huntington, Emery County, UT

  12. 7. Photographic copy of color photograph of NUWC from the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of color photograph of NUWC from the Thames River, 1988, view northwest. Original color negative no. N0211-SP-88(L)-02389.16 on file at photo lab at NUWC, Newport, R.I. Copyright-free. - Naval Undersea Warfare Center, East side of Smith & East Streets between Columbia & South Coves, New London, New London County, CT

  13. 8. Photographic copy of color photograph of NUWC from the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photographic copy of color photograph of NUWC from the Thames River, 1988, view southeast. Original color negative no. N0211-SP-88(L)-02389.4 on file at photo lab at NUWC, Newport, R.I. Copyright-free. - Naval Undersea Warfare Center, East side of Smith & East Streets between Columbia & South Coves, New London, New London County, CT

  14. 9. Photographic copy of aerial photograph of NUWC, 1993, view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photographic copy of aerial photograph of NUWC, 1993, view northwest. Original color negative no. 093(L)-09212.32 on file at photo lab at NUWC, Newport, R.I. Copyright-free. - Naval Undersea Warfare Center, East side of Smith & East Streets between Columbia & South Coves, New London, New London County, CT

  15. Credit WCT. Photographic copy of photograph, view northwest at Test ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view northwest at Test Stand "D" tower with Dd station to right and "neutralization pond" in foreground. Note tunnel entrance way in left background. (JPL negative no. 384-3356-B, 20 November 1962) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  16. Credit WCT. Photographic copy of photograph, low level aerial view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, low level aerial view of Test Stand "D," looking due west, after completion of Dd station installation in 1961. Note Test Stand "D" "neutralization pond" to immediate southeast of tower. (JPL negative no. 384-2997-B, 12 December 1961) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  17. 9. Credit WCT. Photographic copy of photograph, interior view of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Credit WCT. Photographic copy of photograph, interior view of control room under construction in Control and Recording Center Building 4221/E-22. Stairway to tunnel system is in left background. (JPL negative no. 384-1927, 26 May 1959) - Jet Propulsion Laboratory Edwards Facility, Control & Recording Center, Edwards Air Force Base, Boron, Kern County, CA

  18. 1. Photograhic copy of construction drawing 17534 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photograhic copy of construction drawing 175-34 (from record group of Civil Engineering, Hill Air Force Base, Utah). 8x10 negative and print. PRIMER LOADING PLANT SITE. - Ogden Arsenal, North of State Highway 193, East of State Highway 126 & Interstate 15, South of Davis-Weber Canal, Layton, Davis County, UT

  19. 7. Photographic copy of construction drawing 6912279 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of construction drawing 6912-279 (from record group of Civil Engineering, Hill Air Force Base, Utah). 1940. 8x10 negative and print. HILL FIELD, UTAH A.C. PAINT, OIL, & DOPE HOUSE ELEVATIONS AND DETAILS. - Hill Field, Aircraft Paint, Oil & Dope House, 5923 C Avenue, Layton, Davis County, UT

  20. 8. Photographic copy of construction drawing 6912277 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photographic copy of construction drawing 6912-277 (from record group of Civil Engineering, Hill Air Force Base, Utah). 1940. 8x10 negative and print. HILL FIELD, UTAH A.C. PAINT, OIL, & DOPE HOUSE TYPICAL DETAILS. - Hill Field, Aircraft Paint, Oil & Dope House, 5923 C Avenue, Layton, Davis County, UT

  1. 4. Credit WCT. Photographic copy of photograph, test Stand 'B' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Credit WCT. Photographic copy of photograph, test Stand 'B' set up for shock tube and research on ship-to-ship fueling problems for the U.S. Coast Guard. (JPL negative no. 344-3743-A, October or November 1980) - Jet Propulsion Laboratory Edwards Facility, Test Stand B, Edwards Air Force Base, Boron, Kern County, CA

  2. 5. Photographic copy of construction drawing 10989 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photographic copy of construction drawing 109-89 (from record group of Civil Engineering, Hill Air Force Base, Utah). Aug. 30, 1940. 8x10 negative and print. STANDARD SERVICE MAGAZINES & REST HOUSE DETONATOR, TETRYL, BLENDED TETRYL, MERCURY FULMONATE, BLACK POWDER, PLANS, ELEVATION SECTION & DETAILS. - Ogden Arsenal, Rest House, North side of North Carolina Lane, Layton, Davis County, UT

  3. 2. Credit JPL. Photographic copy of photograph, looking northwest at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Credit JPL. Photographic copy of photograph, looking northwest at Test Stand 'B' set up to test a 20,000 pound thrust rocket engine. (JPL negative no. 384-1509-B, 22 October 1956) - Jet Propulsion Laboratory Edwards Facility, Test Stand B, Edwards Air Force Base, Boron, Kern County, CA

  4. Credit WCT. Photographic copy of photograph, oxidizer and fuel tank ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, oxidizer and fuel tank assembly for engine tests being raised by crane for permanent installation in Test Stand "D" tower. Each tank held 170 gallons of propellants. (JPL negative 384-2029-B, 7 August 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  5. Credit WCT. Photographic copy of photograph, view looking southeast across ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view looking southeast across formwork for reinforced concrete base of Test Stand "D," with tunnel extension in foreground. (JPL negative no. 384-1838-D, 9 March 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  6. Credit WCT. Photographic copy of photograph, looking southwest across east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, looking southwest across east side of Test Stand "D" while work is in progress to install conduit for new Dd horizontal test station. (JPL negative no. 384-2248-B, 3 May 1960) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  7. 5. Credit GE. Photographic copy of photograph, completed flame pit ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Credit GE. Photographic copy of photograph, completed flame pit in Test Stand 'A' with steel plate flame deflector over refractory brick. (JPL negative no. 383-1033, 17 January 1946) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  8. 1. Credit GE. Photographic copy of photograph, test Stand 'A' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Credit GE. Photographic copy of photograph, test Stand 'A' reinforced concrete foundation under construction as seen from the southeast. Formwork is being removed as refractory brick lining is being laid in flame pit at the center. (JPL negative no. 383-763, 8 March 1945) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  9. 7. Credit JPL. Photographic copy of photograph, view south on ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Credit JPL. Photographic copy of photograph, view south on west side of Test Stand 'A' during excavation for new intra-stand tunnel system. Note equipment, tanks and piping installed in tower. (JPL negative no. 384-1540-D, 7 January 1957) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  10. 2. Credit GE. Photographic copy of photograph, refractory brick lining ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Credit GE. Photographic copy of photograph, refractory brick lining being laid in Test Stand 'A' flame pit to protect concrete from heat of rocket engine flames. (JPL negative no. 383-764, 8 March 1945) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  11. 10. Credit WCT. Photographic copy of photograph, view looking south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Credit WCT. Photographic copy of photograph, view looking south down axis of westernmost tunnel towards Test Stand 'A' from future site of Control and Recording Center Building 4221/E-22 (at junction of corrugated steel tunnel tubes). (JPL negative no. 384-1838-A, 9 March 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  12. 3. Credit WCT. Photographic copy of photograph, test Stand 'B' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit WCT. Photographic copy of photograph, test Stand 'B' during setup for an engine test, looking northwest. (JPL negative no. 384-9432, 1 May 1972) - Jet Propulsion Laboratory Edwards Facility, Test Stand B, Edwards Air Force Base, Boron, Kern County, CA

  13. 3. Credit WCT. Photographic copy of photograph, view northwest up ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit WCT. Photographic copy of photograph, view northwest up route of tunnel as it is extended north to new construction at Test Stand 'E.' Image made from Test Stand 'D' tower. (JPL negative no. 384-3062-B, 29 January 1962) - Jet Propulsion Laboratory Edwards Facility, Test Stand E, Edwards Air Force Base, Boron, Kern County, CA

  14. 8. Photographic copy of construction drawing 6912306. (From record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photographic copy of construction drawing 6912-306. (From record group of Civil Enginering, Hill Air Force Base, Utah). May 21, 1940, 8'x10' negative and print. HILL FIELD UTAH A.C. OPERATIONS HANGAR AND ANNEXES, ELEVATIONS AND MISCELLANEOUS DETAILS. PART B - Hill Field, Aircraft Operations Hangar, 5970 Southgate Avenue, Layton, Davis County, UT

  15. 7. Photographic copy of construction drawing 6912306 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of construction drawing 6912-306 (from record group of Civil Enginering, Hill Air Force Base, Utah). May 21, 1940, 8'x10' negative and print. HILL FIELD UTAH A.C. OPERATIONS HANGAR AND ANNEXES, ELEVATIONS AND MISCELLANEOUS DETAILS. PART A - Hill Field, Aircraft Operations Hangar, 5970 Southgate Avenue, Layton, Davis County, UT

  16. 3. Credit WCT. Photographic copy of photograph, interior view of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit WCT. Photographic copy of photograph, interior view of Steam Generator Plant 4280/E-81 when Clayton steam generators were being installed in 1972. (JPL negative no. 384-9600, 10 October 1972) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Steam Generator Plant, Edwards Air Force Base, Boron, Kern County, CA

  17. 7. Photographic copy of photograph (ca. 1933), original print and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of photograph (ca. 1933), original print and negative in possession of Selfridge Base Museum, Mt. Clemens, Michigan. NORTHWEST VIEW BAKING ROOM INTERIOR - Selfridge Field, Building No. 129, Wilbur Wright Boulevard at Ash Street, Mount Clemens, Macomb County, MI

  18. 7. Photographic copy of construction drawing 6912132 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of construction drawing 6912132 (from record group of Civil Engineering, Hill Air Force Base, Utah). 1940. 8'x10' negative and print. HILL FIELD, UTAH, QM GAS & OIL HOUSE PLAN, ELEVATIONS, DETAIL & STRUCTURAL. - Hill Field, Quatermaster Gas & Oil House, 7326 Wardleigh Road, Layton, Davis County, UT

  19. 8. Photographic copy of cinstruction drawing 641 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photographic copy of cinstruction drawing 641 (from record group of Civil Engineering, Hill Air Force Base, Utah). June 18, 1941. 8'x10' negative and print. Q.M. GAS & OIL HOUSE PIPING DETAILS. - Hill Field, Quatermaster Gas & Oil House, 7326 Wardleigh Road, Layton, Davis County, UT

  20. Zero-Copy Objects System

    NASA Technical Reports Server (NTRS)

    Burleigh, Scott C.

    2011-01-01

    Zero-Copy Objects System software enables application data to be encapsulated in layers of communication protocol without being copied. Indirect referencing enables application source data, either in memory or in a file, to be encapsulated in place within an unlimited number of protocol headers and/or trailers. Zero-copy objects (ZCOs) are abstract data access representations designed to minimize I/O (input/output) in the encapsulation of application source data within one or more layers of communication protocol structure. They are constructed within the heap space of a Simple Data Recorder (SDR) data store to which all participating layers of the stack must have access. Each ZCO contains general information enabling access to the core source data object (an item of application data), together with (a) a linked list of zero or more specific extents that reference portions of this source data object, and (b) linked lists of protocol header and trailer capsules. The concatenation of the headers (in ascending stack sequence), the source data object extents, and the trailers (in descending stack sequence) constitute the transmitted data object constructed from the ZCO. This scheme enables a source data object to be encapsulated in a succession of protocol layers without ever having to be copied from a buffer at one layer of the protocol stack to an encapsulating buffer at a lower layer of the stack. For large source data objects, the savings in copy time and reduction in memory consumption may be considerable.

  1. To Copy-Protect or Not to Copy-Protect?

    ERIC Educational Resources Information Center

    Sacks, Jonathan

    1985-01-01

    Discusses the issues of software piracy, why people illegally copy software, protection afforded software developers by copyright laws, and current and future methods of disk-based protection built into software by developers and the problems these methods have created. (MBR)

  2. Rawcopy: Improved copy number analysis with Affymetrix arrays

    PubMed Central

    Mayrhofer, Markus; Viklund, Björn; Isaksson, Anders

    2016-01-01

    Microarray data is subject to noise and systematic variation that negatively affects the resolution of copy number analysis. We describe Rawcopy, an R package for processing of Affymetrix CytoScan HD, CytoScan 750k and SNP 6.0 microarray raw intensities (CEL files). Noise characteristics of a large number of reference samples are used to estimate log ratio and B-allele frequency for total and allele-specific copy number analysis. Rawcopy achieves better signal-to-noise ratio and higher proportion of validated alterations than commonly used free and proprietary alternatives. In addition, Rawcopy visualizes each microarray sample for assessment of technical quality, patient identity and genome-wide absolute copy number states. Software and instructions are available at http://rawcopy.org. PMID:27796336

  3. 48 CFR 3401.105-3 - Copies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... GENERAL ED ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 3401.105-3 Copies. Copies of the... EDAR is available for viewing at: http://www.ed.gov/policy/fund/reg/clibrary/edar.html....

  4. 48 CFR 3401.105-3 - Copies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... GENERAL ED ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 3401.105-3 Copies. Copies of the... EDAR is available for viewing at: http://www.ed.gov/policy/fund/reg/clibrary/edar.html....

  5. 48 CFR 3401.105-3 - Copies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... GENERAL ED ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 3401.105-3 Copies. Copies of the... EDAR is available for viewing at: http://www.ed.gov/policy/fund/reg/clibrary/edar.html....

  6. 48 CFR 3401.105-3 - Copies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... GENERAL ED ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 3401.105-3 Copies. Copies of the... EDAR is available for viewing at: http://www.ed.gov/policy/fund/reg/clibrary/edar.html....

  7. 48 CFR 1401.105-3 - Copies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Copies. 1401.105-3 Section 1401.105-3 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 1401.105-3 Copies. Copies of...

  8. 48 CFR 1401.105-3 - Copies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Copies. 1401.105-3 Section 1401.105-3 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 1401.105-3 Copies. Copies of...

  9. 48 CFR 1401.105-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Copies. 1401.105-3 Section 1401.105-3 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 1401.105-3 Copies. Copies of...

  10. 48 CFR 1401.105-3 - Copies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Copies. 1401.105-3 Section 1401.105-3 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 1401.105-3 Copies. Copies of...

  11. 14 CFR 187.7 - Copies; seal.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Copies; seal. 187.7 Section 187.7... REGULATIONS FEES § 187.7 Copies; seal. The fees for furnishing photostatic or similar copies of documents and for affixation of the seal for a certification or validation are the same as those provided in...

  12. 14 CFR 187.7 - Copies; seal.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Copies; seal. 187.7 Section 187.7... REGULATIONS FEES § 187.7 Copies; seal. The fees for furnishing photostatic or similar copies of documents and for affixation of the seal for a certification or validation are the same as those provided in...

  13. 14 CFR 187.7 - Copies; seal.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Copies; seal. 187.7 Section 187.7... REGULATIONS FEES § 187.7 Copies; seal. The fees for furnishing photostatic or similar copies of documents and for affixation of the seal for a certification or validation are the same as those provided in...

  14. 14 CFR 187.7 - Copies; seal.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Copies; seal. 187.7 Section 187.7... REGULATIONS FEES § 187.7 Copies; seal. The fees for furnishing photostatic or similar copies of documents and for affixation of the seal for a certification or validation are the same as those provided in...

  15. 14 CFR 187.7 - Copies; seal.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Copies; seal. 187.7 Section 187.7... REGULATIONS FEES § 187.7 Copies; seal. The fees for furnishing photostatic or similar copies of documents and for affixation of the seal for a certification or validation are the same as those provided in...

  16. 48 CFR 3401.104-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Copies. 3401.104-3 Section 3401.104-3 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 3401.104-3 Copies. Copies of...

  17. 48 CFR 2001.104-3 - Copies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Copies. 2001.104-3 Section 2001.104-3 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 2001.104-3 Copies. Copies...

  18. 48 CFR 2001.104-3 - Copies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Copies. 2001.104-3 Section 2001.104-3 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 2001.104-3 Copies. Copies...

  19. 48 CFR 2001.104-3 - Copies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Copies. 2001.104-3 Section 2001.104-3 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 2001.104-3 Copies. Copies...

  20. 48 CFR 2001.104-3 - Copies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Copies. 2001.104-3 Section 2001.104-3 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 2001.104-3 Copies. Copies...

  1. 48 CFR 2001.104-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Copies. 2001.104-3 Section 2001.104-3 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 2001.104-3 Copies. Copies...

  2. 36 CFR 703.20 - File copies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false File copies. 703.20 Section... Is Not a Party § 703.20 File copies. The Office of the General Counsel will maintain the official file of copies of all demands served on the Library and deciding officials' responses....

  3. Copying and Evolution of Neuronal Topology

    PubMed Central

    Fernando, Chrisantha; Karishma, K. K.; Szathmáry, Eörs

    2008-01-01

    We propose a mechanism for copying of neuronal networks that is of considerable interest for neuroscience for it suggests a neuronal basis for causal inference, function copying, and natural selection within the human brain. To date, no model of neuronal topology copying exists. We present three increasingly sophisticated mechanisms to demonstrate how topographic map formation coupled with Spike-Time Dependent Plasticity (STDP) can copy neuronal topology motifs. Fidelity is improved by error correction and activity-reverberation limitation. The high-fidelity topology-copying operator is used to evolve neuronal topologies. Possible roles for neuronal natural selection are discussed. PMID:19020662

  4. 13. Photographic copy of original construction drawing, sheet no. 10 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photographic copy of original construction drawing, sheet no. 10 of 21, dated November 1, 1940, taken from a 11 x 17 print of a 2 x 2 negative in the possession of the Utah Department of Transportation, Salt Lake City, Utah. ELEVATION UPPER ABUTMENT, SECTIONS, AND DETAIL AND PLAN OF HANDRAILS & POSTS - Huntington Creek Bridge, Spanning Huntington Creek at State Route 10, Huntington, Emery County, UT

  5. 6. Credit GE. Photographic copy of photograph, view looking east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Credit GE. Photographic copy of photograph, view looking east at Test Stand 'A' during test firing of a liquid-fueled Corporal engine. Structure in immediate left foreground of view appears to be a propellant tank enclosure (JPL negative no. 383-1225, July 1945); compare HAER CA-163-A-7 for enclosure. - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  6. 4. Credit GE. Photographic copy of photograph, looking northeast into ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Credit GE. Photographic copy of photograph, looking northeast into 'A' stand flame trench as seen from the southeast corner of 'A' stand foundation. The concrete construction at the bottom of the trench is a water pond with sump for cooling rocket engine plumes before they blow into the desert to the east. (JPL negative no. 383-940-B, 29 August 1945) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  7. Credit WCT. Photographic copy of photograph, view looking northwest at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view looking northwest at complete Test Stand "D" installation as of January 1962. Note closed-circuit television camera at extreme left, along with MMH (fuel) storage tank. Hatch of Dd test cell is open; nearby stand MMH run tanks for Dd station. (JPL negative no. 384-2591-A, 25 January 1961) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  8. Credit WCT. Photographic copy of photograph, view north across "neutralization ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view north across "neutralization pond" at Test Stand "D," showing complete Dd station with new Y-Stage and Z-Stage steam-driven ejectors, and "Hyprox" steam generator which powered ejectors. (JPL negative no. 384-3356-B, 20 November 1962) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  9. Credit WCT. Photographic copy of photograph, view east showing the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view east showing the Y-stage ejector nozzle as the Y-stage ejector is being installed in the Dd ejector train in 1962. In the distance can be seen the western end of the Z-stage ejector. (JPL negative no. 384-3345-A, 8 November 1962) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  10. Credit WCT. Photographic copy of photograph, view looking east at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view looking east at Test Stand "D" during erection of the test stand tower. Note wire lath nailed over gypsum board on Building 4222/E-23 at far left in preparation for stucco covering (temporary construction). Stucco would not require painting in desert. (JPL negative no. 384-1865-A, 13 April 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  11. Photographic copy of photograph, aerial view looking south at Jet ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, aerial view looking south at Jet Propulsion Laboratory, Edwards Test Station complex in 1959, shortly after completion of Test Stand 'D' construction and installation of underground tunnel system. Test Stand 'D' is in the foreground, Test Stand 'A' complex in the background. Roads are as yet unpaved. (JPL negative no. 384-1917-B, 28 May 1959) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  12. Photographic copy of photograph, aerial view looking north at Jet ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, aerial view looking north at Jet Propulsion Laboratory, Edwards Test Station complex in 1959, shortly after completion of 'D' stand construction and installation of underground tunnel system. Test stands 'A,' 'B,' 'C,' and 'D' are in view; the Control and Recording Center (Building 4221/E-22) is still under construction. (JPL negative no. 384-1917-A, 28 May 1959) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  13. Credit WCT. Photographic copy of photograph, view looking north at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view looking north at Test Stand "D" engine exhaust gas deflector or "flame bucket" just after its installation. This device was water-cooled. It also injected sprays of water into the gas flow to cool the exhaust down. (JPL negative no. 384-1861-A, 8 April 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  14. Credit WCT. Photographic copy of photograph, view east southeast across ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view east southeast across Dd station ejectors showing detail of "Hyprox" steam generator. Note that steam generator is placed above Z-stage ejector; an insulated pipe running between the Dd train rails supplies steam to the Y-Stage ejector. Note emergency eyewash stand at extreme right of view. (JPL negative no. 384-3376, 3 December 1962) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  15. Thai Negation.

    ERIC Educational Resources Information Center

    Alam, Samsul

    A study analyzed the structure of negative sentences in the Thai language, based on data gathered from two native speakers. It is shown that the Thai negative marker generally occurs between the noun phrase (subject) and the verb phrase in simple active sentences and in passive sentences. Negation of noun phrases is also allowed in Thai, with a…

  16. 22 CFR 401.13 - Copies required.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Copies required. 401.13 Section 401.13 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.13... additional copies of the documents mentioned therein as may be requested by the Commission shall be...

  17. 22 CFR 401.13 - Copies required.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Copies required. 401.13 Section 401.13 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.13... additional copies of the documents mentioned therein as may be requested by the Commission shall be...

  18. 22 CFR 401.13 - Copies required.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Copies required. 401.13 Section 401.13 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.13... additional copies of the documents mentioned therein as may be requested by the Commission shall be...

  19. 22 CFR 401.13 - Copies required.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Copies required. 401.13 Section 401.13 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.13... additional copies of the documents mentioned therein as may be requested by the Commission shall be...

  20. 22 CFR 401.13 - Copies required.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Copies required. 401.13 Section 401.13 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.13... additional copies of the documents mentioned therein as may be requested by the Commission shall be...

  1. 48 CFR 3001.105-3 - Copies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Copies. 3001.105-3 Section 3001.105-3 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY....105-3 Copies. Official versions of the HSAR are available in the Code of Federal Regulations,...

  2. 48 CFR 3001.105-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....105-3 Copies. The HSAR is available in the Federal Register and electronically at http://www.dhs.gov... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Copies. 3001.105-3 Section 3001.105-3 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND...

  3. 48 CFR 3001.105-3 - Copies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Copies. 3001.105-3 Section 3001.105-3 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY....105-3 Copies. Official versions of the HSAR are available in the Code of Federal Regulations,...

  4. 48 CFR 3001.105-3 - Copies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....105-3 Copies. The HSAR is available in the Federal Register and electronically at http://www.dhs.gov... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Copies. 3001.105-3 Section 3001.105-3 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND...

  5. 48 CFR 201.105-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Copies. 201.105-3 Section 201.105-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 201.105-3 Copies....

  6. 48 CFR 1501.105-3 - Copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Copies. 1501.105-3 Section 1501.105-3 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY GENERAL GENERAL... 20402. Copies of loose-leaf EPAAR are distributed within EPA and may be obtained from the EPA...

  7. NEGATIVE SYMPTOMS AND NEGATIVE SCHIZOPHRENIA

    PubMed Central

    Chaturvedi, S.K.; Gopinath, P.S.; Mathai, P. John; Michael, Albert

    1984-01-01

    SUMMARY This study determines the frequency distribution of prominent negative symptoms in a group of chronic, hospitalised schizophrenics. Thirty chronic Schizophrenic (D.S.M. III) patients were rated on the scale for Assessment of Negative Symptoms (SANS) and the prominent negative symptoms were correlated with age, sex and certain illness variables. Majority (80%) of patients had some or the other negative symptom, except thought blocking which was found in none. The subjective awareness of the symptoms was poor. Most negative symptoms were present to a severe degree in about 40% of cases. However, no significant correlation was found between severe negative symptoms and age or sex. Similarly, duration of illness, duration of hospitalisation or current medications did not influence negative symptoms to any appreciable degree. The implications are discussed. PMID:21965985

  8. 3. Credit GE. Photographic copy of photograph, east elevation of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit GE. Photographic copy of photograph, east elevation of 'A' stand on 29 August 1945. A steel frame has been erected for a travelling hoist, and propellant lines are visible to the right (north) of the stand, rising from storage tanks installed in the north side of the stand. To the east of the flame pit is a concrete water pond and sump designed to cool rocket engine exhaust. Exhaust was directed east in the direction of prevailing winds. (JPL negative no. 383-940-A, 29 August 1945) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  9. Credit WCT. Photographic copy of photograph, interior view of Dd ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, interior view of Dd test cell with VO (Viking Orbiter)-75 spacecraft engine mounted for testing. (Viking was a Mars orbiter and lander mission.) The end of the engine nozzle is inserted into a diffuser in order to conduct exhaust gases out of the chamber. All piping and tubing is stainless steel. Note ports in background through which instrumentation wiring passes. Nozzles at top of view are part of an internal fire suppression (or "Firex") system. (JPL negative no. 384-9428, 24 April 1972) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  10. Credit WCT. Photographic copy of photograph, view of Test Stand ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view of Test Stand "D" from the south with tower ejector system in operation during a 1972 engine test. Note steam evolving from Z-stage ejectors atop the interstage condenser in the tower. Note also the "Hyprox" steam generator straddling the Dd ejector train to the right. The new Dy horizontal train has not been erected as of this date. In the distance is Test Stand "E." (JPL negative no. 384-9766-AC, 28 November 1972) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  11. 8. Credit JPL. Photographic copy of photograph, view west down ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Credit JPL. Photographic copy of photograph, view west down from Test Stand 'A' tower across newly installed tunnel tube to corner of Building 4201/E-2, Test Stand 'A' Workshop (demolished in 1985). Note the wooden retaining structure erected in the foreground to retain earth once the tunnel trench is backfilled (this retaining wall remained in 1994). Note also the propellant control piping on the Test Stand 'A' platform in the immediate foreground. (JPL negative no. 384-1547-C, 6 February 1957) - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  12. Photographic copy of photograph, aerial view looking down at Jet ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, aerial view looking down at Jet Propulsion Laboratory, Edwards Test Station complex in 1961, with north toward the top of the view. Dd test station has been added to Test Stand 'D,' liquid nitrogen storage facility E-63 has been built, as well as several adjuncts to Test Stand 'C' behind earth barriers, such as oxidizer facility at 4263/E-64 and hydrogen tank at 4264/E-65. (JPL negative no. 384-3003-A, 12 December 1961) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  13. 2. Credit JPL. Photographic copy of photograph, looking northeast at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Credit JPL. Photographic copy of photograph, looking northeast at unfinished original Test Stand 'C' construction. A portion of the corrugated steel tunnel tube connecting Test Stand 'C' to the first phase of JPL tunnel system construction is visible in the foreground. The steel frame used to support propellant tanks and engine equipment has been erected. The open trap door leads to a chamber inside the Test Stand 'C' base where gaseous nitrogen is distributed via manifolds to Test Stand 'C' control valves. (JPL negative no. 384-1568-A, 19 March 1957) - Jet Propulsion Laboratory Edwards Facility, Test Stand C, Edwards Air Force Base, Boron, Kern County, CA

  14. Credit WCT. Photographic copy of photograph, view looking south down ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view looking south down easternmost tunnel axis during second phase of JPL tunnel construction in 1959. Reinforced concrete formwork for Test Stand "D" foundation appears in left foreground. Formwork for Building 4222/E-23 (Test Stand "D" Workshop) is in place in right foreground with disturbed earth for western leg of tunnel system evident in background. Test Stand "C" is in center background, where first phase of tunnel construction ended. Test Stand "A" appears as tower in right background. (JPL negative no. 384-1838-C, 9 March 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  15. Credit WCT. Photographic copy of photograph, view of Test Stand ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view of Test Stand "D" from Test Stand "A" while a rocket engine test is in progress. Cloud of steam is from partly from water created by propellant reaction and from water sprayed by flame bucket into engine exhaust for cooling purposes. A portion of Test Stand "C" is visible at the far right. (JPL negative no. 384-2082-B, 23 October 1959) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  16. Photographic copy of photograph, aerial view looking north and showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, aerial view looking north and showing Test Stand 'A' (at bottom), Test Stand 'B' (upper right), and a portion of Test Stand 'C' (top of view). Compare HAER CA-163-1 and 2 and note addition of liquid nitrogen storage tank (Building 4262/E-63) to west of Test Stand 'C' as well as various ancillary facilities located behind earth barriers near Test Stand 'C.' (JPL negative no. 384-3006-A, 12 December 1961) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  17. Credit WCT. Photographic copy of photograph, in 1963 a "Y" ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, in 1963 a "Y" branch connector was introduced at the Dd test station in order to add a second test cell (named Dy) to the Dd train of coolers and ejectors. This view shows the diffuser used to connect the Dy test chamber with the "Y" branch. This Dy chamber was the second one installed at this station; it was later moved and incorporated into a larger horizontal test station retaining the Dy designation. (JPL negative no. 384-11176-B, 17 May 1976) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  18. 3. Credit JPL. Photographic copy of photograph, view south into ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit JPL. Photographic copy of photograph, view south into oxidizer tank enclosure and controls on the north side of Test Stand 'C' shortly after the stand's construction in 1957 (oxidizer contents not determined). To the extreme left appear fittings for mounting an engine for tests. Note the robust stainless steel flanges and fittings necessary to contain highly pressurized corrosive chemicals. (JPL negative no. 384-1608-C, 29 August 1957) - Jet Propulsion Laboratory Edwards Facility, Test Stand C, Edwards Air Force Base, Boron, Kern County, CA

  19. ACTA Technology Presents EPA with Patent Copy

    EPA Pesticide Factsheets

    US EPA SBIR awardee, ACTA Technology, presented James H. Johnson, Director of the US EPA National Center for Environmental Research, and April Richards, Program Manager of the US EPA's SBIR Program, with a copy of their Red Ribbon patent.

  20. Kinetic versus Energetic Discrimination in Biological Copying

    NASA Astrophysics Data System (ADS)

    Sartori, Pablo; Pigolotti, Simone

    2013-05-01

    We study stochastic copying schemes in which discrimination between a right and a wrong match is achieved via different kinetic barriers or different binding energies of the two matches. We demonstrate that, in single-step reactions, the two discrimination mechanisms are strictly alternative and cannot be mixed to further reduce the error fraction. Close to the lowest error limit, kinetic discrimination results in a diverging copying velocity and dissipation per copied bit. On the other hand, energetic discrimination reaches its lowest error limit in an adiabatic regime where dissipation and velocity vanish. By analyzing experimentally measured kinetic rates of two DNA polymerases, T7 and Polγ, we argue that one of them operates in the kinetic and the other in the energetic regime. Finally, we show how the two mechanisms can be combined in copying schemes implementing error correction through a proofreading pathway.

  1. Line copy presentation slides with Kodalith.

    PubMed

    Kraushar, M F; Bailey, B A

    1978-08-01

    Line copy presentation slides with white letters on a blue background can be produced with a two-step process. The slides are more permanent than diazo slides, and the process is faster and less expensive.

  2. NASA printing, duplicating, and copying management handbook

    NASA Technical Reports Server (NTRS)

    1993-01-01

    This handbook provides information and procedures for the implementation of NASA policy and applicable laws and regulations relating to printing, duplicating, and copying. The topics addressed include a description of relevant laws and regulations, authorizations required, and responsible entities for NASA printing, duplicating, and copying. The policy of NASA is to ensure understanding and application of authority and responsibility on printing matters. Where necessary, the handbook clarifies the intent of basic laws and regulations applicable to NASA.

  3. COPI Is Required for Enterovirus 71 Replication

    PubMed Central

    Wang, Jianmin; Wu, Zhiqiang; Jin, Qi

    2012-01-01

    Enterovirus 71 (EV71), a member of the Picornaviridae family, is found in Asian countries where it causes a wide range of human diseases. No effective therapy is available for the treatment of these infections. Picornaviruses undergo RNA replication in association with membranes of infected cells. COPI and COPII have been shown to be involved in the formation of picornavirus-induced vesicles. Replication of several picornaviruses, including poliovirus and Echovirus 11 (EV11), is dependent on COPI or COPII. Here, we report that COPI, but not COPII, is required for EV71 replication. Replication of EV71 was inhibited by brefeldin A and golgicide A, inhibitors of COPI activity. Furthermore, we found EV71 2C protein interacted with COPI subunits by co-immunoprecipitation and GST pull-down assay, indicating that COPI coatomer might be directed to the viral replication complex through viral 2C protein. Additionally, because the pathway is conserved among different species of enteroviruses, it may represent a novel target for antiviral therapies. PMID:22662263

  4. Single copy DNA homology in sea stars.

    PubMed

    Smith, M J; Nicholson, R; Stuerzl, M; Lui, A

    1982-01-01

    The sequence homology in the single copy DNA of sea stars has been measured. Labeled single copy DNA from Pisaster ochraceus was reannealed with excess genomic DNA from P. brevispinus, Evasterias troschelii, Pycnopodia helianthoides, Solaster stimpsoni, and Dermasterias imbricata. Reassociation reactions were performed under two criteria of salt and temperature. The extent of reassociation and thermal denaturation characteristics of hybrid single copy DNA molecules follow classical taxonomic lines. P. brevispinus DNA contains essentially all of the sequences present in P. ochraceus single copy tracer while Evasterias and Pycnopodia DNAs contain 52% and 46% of such sequences respectively. Reciprocal reassociation reactions with labeled Evasterias single copy DNA confirm the amount and fidelity of the sequence homology. There is a small definite reaction of uncertain homology between P. ochraceus single copy DNA and Solaster or Dermasterias DNA. Similarly Solaster DNA contains sequences homologous to approximately 18% of Dermasterias unique DNA. The thermal denaturation temperatures of heteroduplexes indicate that the genera Pisaster and Evasterias diverged shortly after the divergence of the subfamilies Pycnopodiinae and Asteriinae. The two Pisaster species diverged more recently, probably in the most recent quarter of the interval since the separation of the genera Pisaster and Evasterias.

  5. Discussion on copy constructor in C++ programming language

    NASA Astrophysics Data System (ADS)

    Luo, Fafen; Du, Ruiqing

    2011-12-01

    C++ is a widely used object-orientated programming language in the software industry. The purpose of this paper is to discuss concept and application of the copy constructor, a special constructor in C++. As fundamental knowledge, constructor and destructor were introduced at first. Several examples of copy constructor were presented to illustrate concept of copy constructor and its use. Shallow copy and deep copy were also presented. After discussions on copy constructor by analyzing all the examples of copy constructor, the conclusion was made about that how to define a copy constructor and how to use it properly.

  6. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; no date original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Repairs to radial brick chimney, building No. 47, sheet 2 of 2 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  7. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1909 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Proposed arrangement of engine room floor for central power house building No. 47 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  8. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1932 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Power House Building No. 47, concrete, subway grating and steel for floor - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  9. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1973 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Demolition of equipment, building No. 47, plans, sheet 1 of 1 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  10. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1965 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Structural repairs to building No. 47, Masonry and miscellaneous repairs, sheet 3 of 5 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  11. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1918 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Building No. 47 central power plant, proposed general arrangement, sheet No. 1 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  12. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1917 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Building No. 47 central power plant, sheet No. 1 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  13. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1907 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Plan showing floor for basement and support for machinery foundations, central power house building No. 47 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  14. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1945 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Central power plant building No. 47, installation of deaerating feedwater heater, feedwater tower and platforms, sheet 2 of 7 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  15. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1965 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Structural repairs to building No. 47, column replacement and insulation repair, sheet 4 of 5 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  16. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1965 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Structural repairs to building No. 47, masonry and miscellaneous repairs, sheet 2 of 5 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  17. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1941 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Building No. 47, new office space, plan, elevations, section and details, sheet 1 of 2 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  18. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1965 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Structural repairs to building No. 47, roof truss system painting, sheet 1 of 5 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  19. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1980 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Modifications to office space, building No. 47 plans, sections and details, general notes, sheet 2 of 3 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  20. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1905 original architectural drawing located at Building No. 458, NAS Pensacola, Florida)Central power house building No. 47, erection diagram, sheet E-1 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  1. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1940 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Lean-to at south side of building No. 47. Floor plan and details, sheet 1 of 2. - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  2. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1940 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Lean-to at south side of building No. 47, elevations, section and details, sheet 2 of 2 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  3. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1909 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Central power station building No. 47, reinforced concrete floor, location plan, sheet 1 of 7 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  4. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1907 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Central power station building No. 47, General arrangement of machinery - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  5. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1993 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Repair chimney, building No. 47, architectural elevations, exterior plan, details, genera notes, sheet 2 of 3 - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  6. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; mircofilm of 1936 original architectural drawing located located at NARA) Repairs to chimneys, central power plant and naval hospital. - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  7. 15. Photographic copy of construction drawing DP28827 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photographic copy of construction drawing DP-28827 (from record group of Civil Engineering, Hill Air Force Base, Utah). Dec. 16, 1940. 8x10 negative and print. STANDARD BLACK POWDER SCREENING BUILDING. ROOF FRAMING PLAN & DETAILS. - Ogden Arsenal, Black Powder Screening Building, 7745 Navajo Way, Layton, Davis County, UT

  8. 14. Photographic copy of construction drawing 4.3D247 (from record group ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photographic copy of construction drawing 4.3-D-247 (from record group of Civil Engineering, Hill Air Force Base, Utah). Dec. 16, 1940. 8x10 negative and print. STANDARD SERVICE MAGAZINES & REST HOUSES PLANS, ELEVATION, SECTION & DETAILS. - Ogden Arsenal, Black Powder Screening Building, 7745 Navajo Way, Layton, Davis County, UT

  9. Negative Certainty

    ERIC Educational Resources Information Center

    Ariso, José María

    2017-01-01

    The definitions of "negative knowledge" and the studies in this regard published to date have not considered the categorial distinction Wittgenstein established between knowledge and certainty. Hence, the important role that certainty, despite its omission, should have in these definitions and studies has not yet been shown. In this…

  10. Negative Numbers

    ERIC Educational Resources Information Center

    Galbraith, Mary J.

    1974-01-01

    Examination of models for representing integers demonstrates that formal operational thought is required for establishing the operations on integers. Advocated is the use of many models for introducing negative numbers but, apart from addition, it is recommended that operations on integers be delayed until the formal operations stage. (JP)

  11. Mechanisms of change in gene copy number.

    PubMed

    Hastings, P J; Lupski, James R; Rosenberg, Susan M; Ira, Grzegorz

    2009-08-01

    Deletions and duplications of chromosomal segments (copy number variants, CNVs) are a major source of variation between individual humans and are an underlying factor in human evolution and in many diseases, including mental illness, developmental disorders and cancer. CNVs form at a faster rate than other types of mutation, and seem to do so by similar mechanisms in bacteria, yeast and humans. Here we review current models of the mechanisms that cause copy number variation. Non-homologous end-joining mechanisms are well known, but recent models focus on perturbation of DNA replication and replication of non-contiguous DNA segments. For example, cellular stress might induce repair of broken replication forks to switch from high-fidelity homologous recombination to non-homologous repair, thus promoting copy number change.

  12. Gene copy number and malaria biology

    PubMed Central

    Anderson, Tim J.C.; Patel, Jigar; Ferdig, Michael T.

    2010-01-01

    Alteration in gene copy number provides a simple way to change expression levels and alter phenotype. This was fully appreciated by bacteriologists more than 25 years ago, but the extent and implications of copy number polymorphism (CNP) have only recently become apparent in other organisms. New methods demonstrate the ubiquity of CNPs in eukaryotes and their medical importance in humans. CNP is also widespread in the Plasmodium falciparum genome and has an important and underappreciated role in determining phenotype. In this review, we summarize the distribution of CNP, its evolutionary dynamics within populations, its functional importance and its mode of evolution. PMID:19559648

  13. The Effects of Answer Copying on the Ability Level Estimates of Cheater Examinees in Answer Copying Pairs

    ERIC Educational Resources Information Center

    Zopluoglu, Cengiz; Davenport, Ernest C., Jr.

    2011-01-01

    The purpose of this study was to examine the effects of answer copying on the ability level estimates of cheater examinees in answer copying pairs. The study generated answer copying pairs for each of 1440 conditions, source ability (12) x cheater ability (12) x amount of copying (10). The average difference between the ability level estimates…

  14. DUF1220 copy number is associated with schizophrenia risk and severity: implications for understanding autism and schizophrenia as related diseases

    PubMed Central

    Searles Quick, V B; Davis, J M; Olincy, A; Sikela, J M

    2015-01-01

    The copy number of DUF1220, a protein domain implicated in human brain evolution, has been linearly associated with autism severity. Given the possibility that autism and schizophrenia are related disorders, the present study examined DUF1220 copy number variation in schizophrenia severity. There are notable similarities between autism symptoms and schizophrenia negative symptoms, and divergence between autism symptoms and schizophrenia positive symptoms. We therefore also examined DUF1220 copy number in schizophrenia subgroups defined by negative and positive symptom features, versus autistic individuals and controls. In the schizophrenic population (N=609), decreased DUF1220 copy number was linearly associated with increasing positive symptom severity (CON1 P=0.013, HLS1 P=0.0227), an association greatest in adult-onset schizophrenia (CON1 P=0.00155, HLS1 P=0.00361). In schizophrenic males, DUF1220 CON1 subtype copy number increase was associated with increased negative symptom severity (P=0.0327), a finding similar to that seen in autistic populations. Subgroup analyses demonstrated that schizophrenic individuals with predominantly positive symptoms exhibited reduced CON1 copy number compared with both controls (P=0.0237) and schizophrenic individuals with predominantly negative symptoms (P=0.0068). These findings support the view that (1) autism and schizophrenia exhibit both opposing and partially overlapping phenotypes and may represent a disease continuum, (2) variation in DUF1220 copy number contributes to schizophrenia disease risk and to the severity of both disorders, and (3) schizophrenia and autism may be, in part, a harmful by-product of the rapid and extreme evolutionary increase in DUF1220 copy number in the human species. PMID:26670282

  15. Teaching Ad Copy--I and II.

    ERIC Educational Resources Information Center

    Welty, Ward; Vanden Bergh, Bruce G.

    1981-01-01

    Ward Welty notes that the standard advertising course could be improved by including a unit of study in rhetoric, especially Aristotelian rhetoric. Bruce Vanden Bergh reports on research on the differences in creating advertising copy for radio versus the visual media of magazines, newspapers, and television. (RL)

  16. Copies of clinic letters to the family.

    PubMed

    Bartle, D G; Diskin, L; Finlay, F

    2004-11-01

    In April 2004 guidelines were introduced advising that letters to the GP should be copied to parents of young people. A study was carried out to ascertain the views of young people and their parents as to who they felt should receive correspondence after an outpatient appointment.

  17. Genomic characteristics of cattle copy number variations

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We performed a systematic analysis of cattle copy number variations (CNVs) using the Bovine HapMap SNP genotyping data, including 539 animals of 21 modern cattle breeds and 6 outgroups. After correcting genomic waves and considering the trio information, we identified 682 candidate CNV regions (CNVR...

  18. 36 CFR 703.20 - File copies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 703.20 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Testimony by Employees and Production of Documents in Certain Legal Proceedings Where the Library... file of copies of all demands served on the Library and deciding officials' responses....

  19. 36 CFR 703.20 - File copies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 703.20 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Testimony by Employees and Production of Documents in Certain Legal Proceedings Where the Library... file of copies of all demands served on the Library and deciding officials' responses....

  20. 36 CFR 703.20 - File copies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 703.20 Parks, Forests, and Public Property LIBRARY OF CONGRESS DISCLOSURE OR PRODUCTION OF RECORDS OR INFORMATION Testimony by Employees and Production of Documents in Certain Legal Proceedings Where the Library... file of copies of all demands served on the Library and deciding officials' responses....

  1. COPI selectively drives maturation of the early Golgi

    DOE PAGES

    Papanikou, Effrosyni; Day, Kasey J.; Austin, Jotham; ...

    2015-12-28

    COPI coated vesicles carry material between Golgi compartments, but the role of COPI in the secretory pathway has been ambiguous. Previous studies of thermosensitive yeast COPI mutants yielded the surprising conclusion that COPI was dispensable both for the secretion of certain proteins and for Golgi cisternal maturation. To revisit these issues, we optimized the anchor-away method, which allows peripheral membrane proteins such as COPI to be sequestered rapidly by adding rapamycin. Video fluorescence microscopy revealed that COPI inactivation causes an early Golgi protein to remain in place while late Golgi proteins undergo cycles of arrival and departure. These dynamics generatemore » partially functional hybrid Golgi structures that contain both early and late Golgi proteins, explaining how secretion can persist when COPI has been inactivated. Our findings suggest that cisternal maturation involves a COPI-dependent pathway that recycles early Golgi proteins, followed by multiple COPI-independent pathways that recycle late Golgi proteins.« less

  2. Credit WCT. Photographic copy of photograph, view looking northeast down ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, view looking northeast down onto new Dd test station from Test Stand "D" tower. Hatch of Dd test cell is open, and a test engine sits on a dolly nearby awaiting mounting. Note the water-cooled diffuser on the east end of the test chamber; this was soon replaced with a new diffuser and a steam-driven ejector for simulated high-altitude tests. A closed circuit television camera is mounted on the west end of the test cell. At the lower left of the view are fuel and oxidizer run tanks which supply propellants for test runs. (JPL negative no. 384-2650-A, 8 February 1961) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  3. Copy number analysis of NIPBL in a cohort of 510 patients reveals rare copy number variants and a mosaic deletion

    PubMed Central

    Cheng, Yu-Wei; Tan, Christopher A; Minor, Agata; Arndt, Kelly; Wysinger, Latrice; Grange, Dorothy K; Kozel, Beth A; Robin, Nathaniel H; Waggoner, Darrel; Fitzpatrick, Carrie; Das, Soma; del Gaudio, Daniela

    2014-01-01

    Cornelia de Lange syndrome (CdLS) is a genetically heterogeneous disorder characterized by growth retardation, intellectual disability, upper limb abnormalities, hirsutism, and characteristic facial features. In this study we explored the occurrence of intragenic NIPBL copy number variations (CNVs) in a cohort of 510 NIPBL sequence-negative patients with suspected CdLS. Copy number analysis was performed by custom exon-targeted oligonucleotide array-comparative genomic hybridization and/or MLPA. Whole-genome SNP array was used to further characterize rearrangements extending beyond the NIPBL gene. We identified NIPBL CNVs in 13 patients (2.5%) including one intragenic duplication and a deletion in mosaic state. Breakpoint sequences in two patients provided further evidence of a microhomology-mediated replicative mechanism as a potential predominant contributor to CNVs in NIPBL. Patients for whom clinical information was available share classical CdLS features including craniofacial and limb defects. Our experience in studying the frequency of NIBPL CNVs in the largest series of patients to date widens the mutational spectrum of NIPBL and emphasizes the clinical utility of performing NIPBL deletion/duplication analysis in patients with CdLS. PMID:24689074

  4. Laser thermographic technologies for hard copy recording

    NASA Astrophysics Data System (ADS)

    Bessmel'tsev, Viktor P.; Baev, Sergej G.

    1995-04-01

    Methods of hard copies recording based on thermal interaction of the beam from CO2 or YAG lasers with various kinds of films on any substrates have been developed. The recording processes are single-step and require no additional development. Among them are: (1) Laser thermodestruction of thin mask layers or of a material surface on any kinds of substrates. (2) Laser thermochemical reactions of thermal decomposition of metal salts in solid state phase on a surface of various hygroscopic substrates. The laser recording devices using the methods, described above have been developed and are manufactured now; they allow one to record hard copies with a size of up to 27 X 31 inches, a resolution of 4000 dpi.

  5. Colour hard-copy from workstation screens

    NASA Astrophysics Data System (ADS)

    Clayton, C. A.

    It is possible to produce a colour print on the DEC LJ250 inkjet printer of either the entire screen or a portion of the screen from VAXstations, DECstations, SUN workstations and the IKON image display. This document describes how to achieve this with each of the above workstations. The IKONPAINT software which is used to produce colour hard-copy from the IKON screen on the inkjet printer is fully documented in SUN/71 and is not described here.

  6. Modeling genetic inheritance of copy number variations

    PubMed Central

    Wang, Kai; Chen, Zhen; Tadesse, Mahlet G.; Glessner, Joseph; Grant, Struan F. A.; Hakonarson, Hakon; Bucan, Maja

    2008-01-01

    Copy number variations (CNVs) are being used as genetic markers or functional candidates in gene-mapping studies. However, unlike single nucleotide polymorphism or microsatellite genotyping techniques, most CNV detection methods are limited to detecting total copy numbers, rather than copy number in each of the two homologous chromosomes. To address this issue, we developed a statistical framework for intensity-based CNV detection platforms using family data. Our algorithm identifies CNVs for a family simultaneously, thus avoiding the generation of calls with Mendelian inconsistency while maintaining the ability to detect de novo CNVs. Applications to simulated data and real data indicate that our method significantly improves both call rates and accuracy of boundary inference, compared to existing approaches. We further illustrate the use of Mendelian inheritance to infer SNP allele compositions in each of the two homologous chromosomes in CNV regions using real data. Finally, we applied our method to a set of families genotyped using both the Illumina HumanHap550 and Affymetrix genome-wide 5.0 arrays to demonstrate its performance on both inherited and de novo CNVs. In conclusion, our method produces accurate CNV calls, gives probabilistic estimates of CNV transmission and builds a solid foundation for the development of linkage and association tests utilizing CNVs. PMID:18832372

  7. Digital authentication with copy-detection patterns

    NASA Astrophysics Data System (ADS)

    Picard, Justin

    2004-06-01

    Technologies for making high-quality copies of documents are getting more available, cheaper, and more efficient. As a result, the counterfeiting business engenders huge losses, ranging to 5% to 8% of worldwide sales of brand products, and endangers the reputation and value of the brands themselves. Moreover, the growth of the Internet drives the business of counterfeited documents (fake IDs, university diplomas, checks, and so on), which can be bought easily and anonymously from hundreds of companies on the Web. The incredible progress of digital imaging equipment has put in question the very possibility of verifying the authenticity of documents: how can we discern genuine documents from seemingly "perfect" copies? This paper proposes a solution based on creating digital images with specific properties, called a Copy-detection patterns (CDP), that is printed on arbitrary documents, packages, etc. CDPs make an optimal use of an "information loss principle": every time an imae is printed or scanned, some information is lost about the original digital image. That principle applies even for the highest quality scanning, digital imaging, printing or photocopying equipment today, and will likely remain true for tomorrow. By measuring the amount of information contained in a scanned CDP, the CDP detector can take a decision on the authenticity of the document.

  8. CONTRA: copy number analysis for targeted resequencing

    PubMed Central

    Li, Jason; Lupat, Richard; Amarasinghe, Kaushalya C.; Thompson, Ella R.; Doyle, Maria A.; Ryland, Georgina L.; Tothill, Richard W.; Halgamuge, Saman K.; Campbell, Ian G.; Gorringe, Kylie L.

    2012-01-01

    Motivation: In light of the increasing adoption of targeted resequencing (TR) as a cost-effective strategy to identify disease-causing variants, a robust method for copy number variation (CNV) analysis is needed to maximize the value of this promising technology. Results: We present a method for CNV detection for TR data, including whole-exome capture data. Our method calls copy number gains and losses for each target region based on normalized depth of coverage. Our key strategies include the use of base-level log-ratios to remove GC-content bias, correction for an imbalanced library size effect on log-ratios, and the estimation of log-ratio variations via binning and interpolation. Our methods are made available via CONTRA (COpy Number Targeted Resequencing Analysis), a software package that takes standard alignment formats (BAM/SAM) and outputs in variant call format (VCF4.0), for easy integration with other next-generation sequencing analysis packages. We assessed our methods using samples from seven different target enrichment assays, and evaluated our results using simulated data and real germline data with known CNV genotypes. Availability and implementation: Source code and sample data are freely available under GNU license (GPLv3) at http://contra-cnv.sourceforge.net/ Contact: Jason.Li@petermac.org Supplementary information: Supplementary data are available at Bioinformatics online. PMID:22474122

  9. Clinical relevance of copy number profiling in oral and oropharyngeal squamous cell carcinoma.

    PubMed

    van Kempen, Pauline M W; Noorlag, Rob; Braunius, Weibel W; Moelans, Cathy B; Rifi, Widad; Savola, Suvi; Koole, Ronald; Grolman, Wilko; van Es, Robert J J; Willems, Stefan M

    2015-10-01

    Current conventional treatment modalities in head and neck squamous cell carcinoma (HNSCC) are nonselective and have shown to cause serious side effects. Unraveling the molecular profiles of head and neck cancer may enable promising clinical applications that pave the road for personalized cancer treatment. We examined copy number status in 36 common oncogenes and tumor suppressor genes in a cohort of 191 oropharyngeal squamous cell carcinomas (OPSCC) and 164 oral cavity squamous cell carcinomas (OSCC) using multiplex ligation probe amplification. Copy number status was correlated with human papillomavirus (HPV) status in OPSCC, with occult lymph node status in OSCC and with patient survival. The 11q13 region showed gain or amplifications in 59% of HPV-negative OPSCC, whereas this amplification was almost absent in HPV-positive OPSCC. Additionally, in clinically lymph node-negative OSCC (Stage I-II), gain of the 11q13 region was significantly correlated with occult lymph node metastases with a negative predictive value of 81%. Multivariate survival analysis revealed a significantly decreased disease-free survival in both HPV-negative and HPV-positive OPSCC with a gain of Wnt-induced secreted protein-1. Gain of CCND1 showed to be an independent predictor for worse survival in OSCC. These results show that copy number aberrations, mainly of the 11q13 region, may be important predictors and prognosticators which allow for stratifying patients for personalized treatment of HNSCC.

  10. 19 CFR 151.64 - Extra copy of entry summary.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Wool and Hair § 151.64 Extra copy of entry summary. One extra copy of the entry summary covering wool or hair subject to duty at a rate...

  11. 19 CFR 151.64 - Extra copy of entry summary.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Wool and Hair § 151.64 Extra copy of entry summary. One extra copy of the entry summary covering wool or hair subject to duty at a rate...

  12. 19 CFR 151.64 - Extra copy of entry summary.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Wool and Hair § 151.64 Extra copy of entry summary. One extra copy of the entry summary covering wool or hair subject to duty at a rate...

  13. 19 CFR 151.64 - Extra copy of entry summary.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Wool and Hair § 151.64 Extra copy of entry summary. One extra copy of the entry summary covering wool or hair subject to duty at a rate...

  14. 19 CFR 151.64 - Extra copy of entry summary.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... TREASURY (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Wool and Hair § 151.64 Extra copy of entry summary. One extra copy of the entry summary covering wool or hair subject to duty at a rate...

  15. 19 CFR 133.42 - Infringing copies or phonorecords.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Referral to the U.S. Attorney. In the event that phonorecords or copies of motion pictures arrive in the U... trafficking in counterfeit labels for phonorecords or copies of motion pictures or other audiovisual works...

  16. Most Cancers Caused by Random DNA Copying Errors

    MedlinePlus

    ... fullstory_164252.html Most Cancers Caused by Random DNA Copying Errors While habits, environment can be key ... factors, genes inherited from parents, or simply random DNA copying errors. From their calculations, the researchers now ...

  17. 9. Photocopy of measured drawing (from a copy of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopy of measured drawing (from a copy of the original; copy in accompanying field records, location of original unknown) Adolf Scherrer, architect ca. 1906 'CROSS SECTION' - Maennerchor Building, 102 West Michigan Street, Indianapolis, Marion County, IN

  18. 17 CFR 230.402 - Number of copies; binding; signatures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... copy shall be bound, in one or more parts, without stiff covers. The binding shall be made on the side... filed with the Commission. Each copy shall be bound, in one or more parts, without stiff covers....

  19. 40 CFR 262.22 - Number of copies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE The Manifest § 262.22 Number of copies. The manifest consists of at least the number of copies which will provide the generator, each transporter, and the owner... returned to the generator....

  20. 40 CFR 262.22 - Number of copies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE The Manifest § 262.22 Number of copies. The manifest consists of at least the number of copies which will provide the generator, each transporter, and the owner... returned to the generator....

  1. 40 CFR 262.22 - Number of copies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE The Manifest § 262.22 Number of copies. The manifest consists of at least the number of copies which will provide the generator, each transporter, and the owner... returned to the generator....

  2. 40 CFR 262.22 - Number of copies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE The Manifest § 262.22 Number of copies. The manifest consists of at least the number of copies which will provide the generator, each transporter, and the owner... returned to the generator....

  3. 40 CFR 262.22 - Number of copies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE The Manifest § 262.22 Number of copies. The manifest consists of at least the number of copies which will provide the generator, each transporter, and the owner... returned to the generator....

  4. Conditionally amplifiable BACs: switching from single-copy to high-copy vectors and genomic clones.

    PubMed

    Wild, Jadwiga; Hradecna, Zdenka; Szybalski, Waclaw

    2002-09-01

    The widely used, very-low-copy BAC (bacterial artificial chromosome) vectors are the mainstay of present genomic research. The principal advantage of BACs is the high stability of inserted clones, but an important disadvantage is the low yield of DNA, both for vectors alone and when carrying genomic inserts. We describe here a novel class of single-copy/high-copy (SC/HC) pBAC/oriV vectors that retain all the advantages of low-copy BAC vectors, but are endowed with a conditional and tightly controlled oriV/TrfA amplification system that allows: (1) a yield of ~100 copies of the vector per host cell when conditionally induced with L-arabinose, and (2) analogous DNA amplification (only upon induction and with copy number depending on the insert size) of pBAC/oriV clones carrying >100-kb inserts. Amplifiable clones and libraries facilitate high-throughput DNA sequencing and other applications requiring HC plasmid DNA. To turn on DNA amplification, which is driven by the oriV origin of replication, we used copy-up mutations in the gene trfA whose expression was very tightly controlled by the araC-P(araBAD) promoter/regulator system. This system is inducible by L-arabinose, and could be further regulated by glucose and fucose. Amplification of DNA upon induction with L-arabinose and its modulation by glucose are robust and reliable. Furthermore, we discovered that addition of 0.2% D-glucose to the growth medium helped toward the objective of obtaining a real SC state for all BAC systems, thus enhancing the stability of their maintenance, which became equivalent to cloning into the host chromosome

  5. Host Genetic Variants and Gene Expression Patterns Associated with Epstein-Barr Virus Copy Number in Lymphoblastoid Cell Lines

    PubMed Central

    Houldcroft, Charlotte J.; Petrova, Velislava; Liu, Jimmy Z.; Frampton, Dan; Anderson, Carl A.; Gall, Astrid; Kellam, Paul

    2014-01-01

    Lymphoblastoid cell lines (LCLs) are commonly used in molecular genetics, supplying DNA for the HapMap and 1000 Genomes Projects, used to test chemotherapeutic agents, and informing the basis of a number of population genetics studies of gene expression. The process of transforming human B cells into LCLs requires the presence of Epstein-Barr virus (EBV), a double-stranded DNA virus which through B-cell immortalisation maintains an episomal virus genome in every cell of an LCL at variable copy numbers. Previous studies have reported that EBV alters host-gene expression and EBV copy number may be under host genetic control. We performed a genome-wide association study of EBV genome copy number in LCLs and found the phenotype to be highly heritable, although no individual SNPs achieved a significant association with EBV copy number. The expression of two host genes (CXCL16 and AGL) was positively correlated and expression of ADARB2 was negatively correlated with EBV copy number in a genotype-independent manner. This study shows an association between EBV copy number and the gene expression profile of LCLs, and suggests that EBV copy number should be considered as a covariate in future studies of host gene expression in LCLs. PMID:25290448

  6. 1 CFR 18.1 - Original and copies required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Original and copies required. 18.1 Section 18.1... PROCESSING OF DOCUMENTS PREPARATION AND TRANSMITTAL OF DOCUMENTS GENERALLY § 18.1 Original and copies... two duplicate originals or certified copies. 1 However, if the document is printed or processed...

  7. 1 CFR 18.1 - Original and copies required.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Original and copies required. 18.1 Section 18.1... PROCESSING OF DOCUMENTS PREPARATION AND TRANSMITTAL OF DOCUMENTS GENERALLY § 18.1 Original and copies... two duplicate originals or certified copies. 1 However, if the document is printed or processed...

  8. 12 CFR 269b.730 - Number of copies; form.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Number of copies; form. 269b.730 Section 269b... SYSTEM (CONTINUED) CHARGES OF UNFAIR LABOR PRACTICES General Rules § 269b.730 Number of copies; form... filed with four copies in addition to the original. All matters filed shall be printed, typed,...

  9. 12 CFR 269b.730 - Number of copies; form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Number of copies; form. 269b.730 Section 269b... SYSTEM CHARGES OF UNFAIR LABOR PRACTICES General Rules § 269b.730 Number of copies; form. Except as... copies in addition to the original. All matters filed shall be printed, typed, or otherwise...

  10. Writing Wrongs: Copying as a Strategy for Underachieving EFL Writers.

    ERIC Educational Resources Information Center

    Porte, Graeme K.

    1995-01-01

    This paper reports on a small-scale study of the outcomes generated by 15 underachieving English-as-a-Foreign-Language university writers copying text displayed on a computer monitor under pressure of time. Analysis of student's copied texts showed that various inaccuracies that were not in the original had passed into the copied version,…

  11. Syllables as Functional Units in a Copying Task

    ERIC Educational Resources Information Center

    Kandel, Sonia; Valdois, Sylviane

    2006-01-01

    This research used a copying task to study spelling acquisition from a perception and action perspective. First to fifth graders copied words and pseudo-words on a digitiser. Simultaneously, a camera registered the children's gaze lifts. First and second graders copied the first syllable and then produced a gaze lift to obtain information on the…

  12. Readability as a Factor in Magazine Ad Copy Recall.

    ERIC Educational Resources Information Center

    Wesson, David A.

    1989-01-01

    Examines the relationship between advertising copy readability and advertising effectiveness. Finds that recall is improved when the copy style is either fairly easy or fairly hard to read. Suggests the value of considering copy readability as a potential contributor, though a minor one, to the success of magazine advertising. (RS)

  13. 7 CFR 46.42 - Copies of records; how obtained.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Copies of records; how obtained. 46.42 Section 46.42 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Records § 46.42 Copies of records; how obtained. Copies of records pertaining to licensees under the...

  14. Copy Number Heterogeneity of JC Virus Standards

    PubMed Central

    Bateman, Allen C.; Atienza, Ederlyn E.; Wendt, Sharon; Makhsous, Negar; Jerome, Keith R.; Cook, Linda

    2016-01-01

    ABSTRACT Quantitative PCR is a diagnostic mainstay of clinical virology, and accurate quantitation of viral load among labs requires the use of international standards. However, the use of multiple passages of viral isolates to obtain sufficient material for international standards may result in genomic changes that complicate their use as quantitative standards. We performed next-generation sequencing to obtain single-nucleotide resolution and relative copy number of JC virus (JCV) clinical standards. Strikingly, the WHO international standard and the Exact v1/v2 prototype standards for JCV showed 8-fold and 4-fold variation in genomic coverage between different loci in the viral genome, respectively, due to large deletions in the large T antigen region. Intriguingly, several of the JCV standards sequenced in this study with large T antigen deletions were cultured in cell lines immortalized using simian virus 40 (SV40) T antigen, suggesting the possibility of transcomplementation in cell culture. Using a cutoff 5% allele fraction for junctional reads, 7 different rearrangements were present in the JC virus sequences present in the WHO standard across multiple library preparations and sequencing runs. Neither the copy number differences nor the rearrangements were observed in a clinical sample with a high copy number of JCV or a plasmid control. These results were also confirmed by the quantitative real-time PCR (qPCR), droplet digital PCR (ddPCR), and Sanger sequencing of multiple rearrangements. In summary, targeting different regions of the same international standard can result in up to an 8-fold difference in quantitation. We recommend the use of next-generation sequencing to validate standards in clinical virology. PMID:27974546

  15. 65. March 1978. Copy of enlargement from original 11Omm blackandwhite ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. March 1978. Copy of enlargement from original 11Omm black-and-white aerial negative from Sortie 414, made by United States Air Force, Tactical Reconaissance Wing, Ninth Air Force, at Shaw Air Force Base, Sumter, South Carolina. Overhead aerial view of Borough House with surrounding grounds and adjacent properties. - Borough House, West Side State Route 261, about .1 mile south side of junction with old Garners Ferry Road, Stateburg, Sumter County, SC

  16. Photocopy of drawing (this photograph is and 8' x10' copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing (this photograph is and 8' x10' copy of an 8' x 10' negative; 1940 original architectural drawing located at Building No. 458, NAS Pensacola, Florida) Central power plant building No. 47, electrical work, salt water pumps, auxiliary bus and fire pump, plan, details and changes, sheet 1 of 1. - U.S. Naval Air Station, Power Plant, 328 South Avenue, Pensacola, Escambia County, FL

  17. Getting DNA copy numbers without control samples

    PubMed Central

    2012-01-01

    Background The selection of the reference to scale the data in a copy number analysis has paramount importance to achieve accurate estimates. Usually this reference is generated using control samples included in the study. However, these control samples are not always available and in these cases, an artificial reference must be created. A proper generation of this signal is crucial in terms of both noise and bias. We propose NSA (Normality Search Algorithm), a scaling method that works with and without control samples. It is based on the assumption that genomic regions enriched in SNPs with identical copy numbers in both alleles are likely to be normal. These normal regions are predicted for each sample individually and used to calculate the final reference signal. NSA can be applied to any CN data regardless the microarray technology and preprocessing method. It also finds an optimal weighting of the samples minimizing possible batch effects. Results Five human datasets (a subset of HapMap samples, Glioblastoma Multiforme (GBM), Ovarian, Prostate and Lung Cancer experiments) have been analyzed. It is shown that using only tumoral samples, NSA is able to remove the bias in the copy number estimation, to reduce the noise and therefore, to increase the ability to detect copy number aberrations (CNAs). These improvements allow NSA to also detect recurrent aberrations more accurately than other state of the art methods. Conclusions NSA provides a robust and accurate reference for scaling probe signals data to CN values without the need of control samples. It minimizes the problems of bias, noise and batch effects in the estimation of CNs. Therefore, NSA scaling approach helps to better detect recurrent CNAs than current methods. The automatic selection of references makes it useful to perform bulk analysis of many GEO or ArrayExpress experiments without the need of developing a parser to find the normal samples or possible batches within the data. The method is

  18. Stolen and lost copies of Vesalius's Fabrica.

    PubMed

    Steeno, Omer; Biesbrouck, Maurits

    2012-01-01

    Thefts and losses of precious books are not rare. Here we report several incidents concerning vesalius's Fabrica: the fire of the University Library of Leuven in Belgium, the fate of the collection of the Leopoldina Library of Halle in Germany, the thefts from the Crerar Library in Chicago and in Christ Church College in Oxford, the disappearance of an exceptionally beautiful 'royal' copy from the Castle of Argenteuil (Belgium), and other Fabrica's missing at the Franeker Library in the Netherlands and at the Library of oradea in West Romania. Finally the means of protecting precious book collections are discussed in short as well as the importance of book identification.

  19. To Copy or Not to Copy for Teaching and Scholarship: What Shall I Tell My Client?

    ERIC Educational Resources Information Center

    Cardozo, Michael H.

    1976-01-01

    A clear description of what educators, administrators, or students may and may not copy under the various provisions of the Copyright Law Revision of 1976 is attempted, but the author concludes that the language of the law itself makes such a description impossible. (LBH)

  20. Imitation in Young Children: When Who Gets Copied Is More Important than What Gets Copied

    ERIC Educational Resources Information Center

    Nielsen, Mark; Blank, Cornelia

    2011-01-01

    Unlike other animals, human children will copy all of an adult's goal-directed actions, including ones that are clearly unnecessary for achieving the demonstrated goal. Here we highlight how social affiliation is key to this species-specific behavior. Preschoolers watched 2 adults retrieve a toy from a novel apparatus. One adult included…

  1. The standardised copy of pentagons test

    PubMed Central

    2011-01-01

    Background The 'double-diamond copy' task is a simple paper and pencil test part of the Bender-Gestalt Test and the Mini Mental State Examination (MMSE). Although it is a widely used test, its method of scoring is crude and its psychometric properties are not adequately known. The aim of the present study was to develop a sensitive and reliable method of administration and scoring. Methods The study sample included 93 normal control subjects (53 women and 40 men) aged 35.87 ± 12.62 and 127 patients suffering from schizophrenia (54 women and 73 men) aged 34.07 ± 9.83. Results The scoring method was based on the frequencies of responses of healthy controls and proved to be relatively reliable with Cronbach's α equal to 0.61, test-retest correlation coefficient equal to 0.41 and inter-rater reliability equal to 0.52. The factor analysis produced two indices and six subscales of the Standardised Copy of Pentagons Test (SCPT). The total score as well as most of the individual items and subscales distinguished between controls and patients. The discriminant function correctly classified 63.44% of controls and 75.59% of patients. Discussion The SCPT seems to be a satisfactory, reliable and valid instrument, which is easy to administer, suitable for use in non-organic psychiatric patients and demands minimal time. Further research is necessary to test its psychometric properties and its usefulness and applications as a neuropsychological test. PMID:21481250

  2. Copy-move forgery detection in digital image

    NASA Astrophysics Data System (ADS)

    Alamro, Loai; Yusoff, Nooraini

    2016-08-01

    Copy-move is considered as one of the most popular kind of digital image tempering, in which one or more parts of a digital image are copied and pasted into different locations. Geometric transformation is among the major challenges in detecting copy-move forgery of a digital image. In such forgery, the copied and moved parts of a forged image are either rotated or/and re-scaled. Hence, in this study we propose a combination of Discrete Wavelet Transform (DWT) and Speeded Up Robust Features (SURF) to detect a copy-move activity. The experiments results prove that the proposed method is superior with overall accuracy 95%. The copy-move attacks in digital image has been successfully detected and the method is also can detect the fraud parts exposed to rotation and scaling issue.

  3. 38 CFR 1.526 - Copies of records and papers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... papers. 1.526 Section 1.526 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Copies of records and papers. (a) Any person desiring a copy of any record or document in the custody of... plain one-sided paper copies of a standard size (81/2″ × 11″; 81/2″ × 14″; 11″ × 14″) $0.15 per...

  4. 38 CFR 1.526 - Copies of records and papers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... papers. 1.526 Section 1.526 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Copies of records and papers. (a) Any person desiring a copy of any record or document in the custody of... plain one-sided paper copies of a standard size (81/2″ × 11″; 81/2″ × 14″; 11″ × 14″) $0.15 per...

  5. 38 CFR 1.526 - Copies of records and papers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... papers. 1.526 Section 1.526 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Copies of records and papers. (a) Any person desiring a copy of any record or document in the custody of... plain one-sided paper copies of a standard size (81/2″ × 11″; 81/2″ × 14″; 11″ × 14″) $0.15 per...

  6. 40 CFR 716.30 - Submission of copies of studies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Submission of copies of studies. 716... SUBSTANCES CONTROL ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.30 Submission of copies of studies. (a)(1) Except as provided in §§ 716.5, 716.20, and 716.50, persons must send to EPA copies of...

  7. 11. Photocopy of photograph in the collection of Photographic Branch, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photocopy of photograph in the collection of Photographic Branch, Puget Sound Naval Shipyard, Bremerton, WA. Original is labelled: Yard Photo 42. Date unknown, probably 1940's. Photographer unknown. HABS negative is a 4x5' copy negative. Perspective view of NE corner of Building 78. - Puget Sound Naval Shipyard, Administration Building, Farragut Avenue, Bremerton, Kitsap County, WA

  8. COPI selectively drives maturation of the early Golgi

    PubMed Central

    Papanikou, Effrosyni; Day, Kasey J; Austin, Jotham; Glick, Benjamin S

    2015-01-01

    COPI coated vesicles carry material between Golgi compartments, but the role of COPI in the secretory pathway has been ambiguous. Previous studies of thermosensitive yeast COPI mutants yielded the surprising conclusion that COPI was dispensable both for the secretion of certain proteins and for Golgi cisternal maturation. To revisit these issues, we optimized the anchor-away method, which allows peripheral membrane proteins such as COPI to be sequestered rapidly by adding rapamycin. Video fluorescence microscopy revealed that COPI inactivation causes an early Golgi protein to remain in place while late Golgi proteins undergo cycles of arrival and departure. These dynamics generate partially functional hybrid Golgi structures that contain both early and late Golgi proteins, explaining how secretion can persist when COPI has been inactivated. Our findings suggest that cisternal maturation involves a COPI-dependent pathway that recycles early Golgi proteins, followed by multiple COPI-independent pathways that recycle late Golgi proteins. DOI: http://dx.doi.org/10.7554/eLife.13232.001 PMID:26709839

  9. Photographic copy of photograph, view looking northeast of JPL Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, view looking northeast of JPL Edwards Test Station as it looked in 1945. To the immediate right of the Test Stand 'A' tower stands a concrete monitor building or blockhouse (now Building 4203/E-4) for observation and control of tests. Other frame buildings housed workshop and administrative functions. Long structure behind automobiles was designated 4207/E-8 and was used for instrument repair and storage, a cafeteria, machine and welding shops. To the immediate south of 4207/E-8 were 4200/E-1 (used as an office and photographic laboratory) and 4205/E-6 (guardhouse, with fire extinguisher mounted on it). To the northeast of 4205/E-6 was 4204/E-5 (a propellant storage dock, with shed roof). Buildings 4200/E-1, 4205/E-6 and 4207/E-8 were demolished in 1983. Note the absence of trees. (JPL negative no. 383-1297, July 1946) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  10. Credit WCT. Photographic copy of photograph, low level aerial view ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit WCT. Photographic copy of photograph, low level aerial view of Test Stand "D," looking due south, after completion of Dd station installation in 1961. Note Test Stand "D" "neutralization pond" to immediate southeast of tower. A steel barrier north of and parallel to the Dd station separates fuel run tanks (on south side obscured from view) from oxidizer run tanks (on north side). Small Dj injector test stand is visible to the immediate left of oxidizer run tanks; it is oriented on a northeast/southwest diagonal to the Dd test station. The large tank to the north of the oxidizer run tanks (near center bottom of view) is an oxidizer storage tank for nitrogen tetroxide. Slender tanks to the northwest of the tower (lower right of view) contain high pressure nitrogen gas. A large vertical tank at the base of the tower contains distilled water for flushing propellant lines. (JPL negative no. 384-2997-B, 12 December 1961) - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  11. Schizophrenia copy number variants and associative learning.

    PubMed

    Clifton, N E; Pocklington, A J; Scholz, B; Rees, E; Walters, J T R; Kirov, G; O'Donovan, M C; Owen, M J; Wilkinson, L S; Thomas, K L; Hall, J

    2017-02-01

    Large-scale genomic studies have made major progress in identifying genetic risk variants for schizophrenia. A key finding from these studies is that there is an increased burden of genomic copy number variants (CNVs) in schizophrenia cases compared with controls. The mechanism through which these CNVs confer risk for the symptoms of schizophrenia, however, remains unclear. One possibility is that schizophrenia risk CNVs impact basic associative learning processes, abnormalities of which have long been associated with the disorder. To investigate whether genes in schizophrenia CNVs impact on specific phases of associative learning we combined human genetics with experimental gene expression studies in animals. In a sample of 11 917 schizophrenia cases and 16 416 controls, we investigated whether CNVs from patients with schizophrenia are enriched for genes expressed during the consolidation, retrieval or extinction of associative memories. We show that CNVs from cases are enriched for genes expressed during fear extinction in the hippocampus, but not genes expressed following consolidation or retrieval. These results suggest that CNVs act to impair inhibitory learning in schizophrenia, potentially contributing to the development of core symptoms of the disorder.

  12. Schizophrenia copy number variants and associative learning

    PubMed Central

    Clifton, N E; Pocklington, A J; Scholz, B; Rees, E; Walters, J T R; Kirov, G; O'Donovan, M C; Owen, M J; Wilkinson, L S; Thomas, K L; Hall, J

    2017-01-01

    Large-scale genomic studies have made major progress in identifying genetic risk variants for schizophrenia. A key finding from these studies is that there is an increased burden of genomic copy number variants (CNVs) in schizophrenia cases compared with controls. The mechanism through which these CNVs confer risk for the symptoms of schizophrenia, however, remains unclear. One possibility is that schizophrenia risk CNVs impact basic associative learning processes, abnormalities of which have long been associated with the disorder. To investigate whether genes in schizophrenia CNVs impact on specific phases of associative learning we combined human genetics with experimental gene expression studies in animals. In a sample of 11 917 schizophrenia cases and 16 416 controls, we investigated whether CNVs from patients with schizophrenia are enriched for genes expressed during the consolidation, retrieval or extinction of associative memories. We show that CNVs from cases are enriched for genes expressed during fear extinction in the hippocampus, but not genes expressed following consolidation or retrieval. These results suggest that CNVs act to impair inhibitory learning in schizophrenia, potentially contributing to the development of core symptoms of the disorder. PMID:27956746

  13. 48 CFR 6302.25 - Copies of papers (Rule 25).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Copies of papers (Rule 25). 6302.25 Section 6302.25 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.25 Copies of papers (Rule 25). When books, records, papers,...

  14. 1. Historic American Buildings Survey Copy photo: Albern Color Research, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Copy photo: Albern Color Research, Inc., Philadelphia, July 1960 COPY OF A PHOTOGRAPH TAKEN ca. 1904 SHOWING PART OF THE ENFIELD, NEW HAMPSHIRE SHAKER COMMUNITY WITH THE GREAT STONE HOUSE IN THE CENTER - Shaker Church Family General Views, State Route 4A, Enfield, Grafton County, NH

  15. An Evidence-Informed Picture of Course-Related Copying

    ERIC Educational Resources Information Center

    Graham, Rumi

    2016-01-01

    Recent changes in Canadian copyright law have prompted Canada's educational institutions to reexamine their need for a blanket copying license. Users' rights under the amended Copyright Act now include fair dealing for purposes of education, and the Supreme Court has established that copying short excerpts for classroom use can qualify as fair…

  16. 28. Photographic copy of original construction drawing, dated May 22, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photographic copy of original construction drawing, dated May 22, 1951 (from paper copy at Engineer Flight, Ellsworth Air Force Base, SD). Readiness hangar architectural : building sections & details. - Ellsworth Air Force Base, Readiness Hangar, Kenny Road, southeast corner of interstction with G Avenue, Blackhawk, Meade County, SD

  17. 48 CFR 6302.25 - Copies of papers (Rule 25).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Copies of papers (Rule 25). 6302.25 Section 6302.25 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.25 Copies of papers (Rule 25). When books, records, papers,...

  18. 7 CFR 510.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Public inspection, copying, and indexing. 510.2 Section 510.2 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE PUBLIC INFORMATION § 510.2 Public inspection, copying, and indexing....

  19. 7 CFR 3701.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Public inspection, copying, and indexing. 3701.2 Section 3701.2 Agriculture Regulations of the Department of Agriculture (Continued) ECONOMIC RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE PUBLIC INFORMATION § 3701.2 Public inspection, copying, and indexing....

  20. 7 CFR 3404.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Public inspection, copying, and indexing. 3404.2 Section 3404.2 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE... inspection, copying, and indexing. 5 U.S.C. 552(a)(2) requires that certain materials be made available...

  1. 7 CFR 3801.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Public inspection, copying, and indexing. 3801.2 Section 3801.2 Agriculture Regulations of the Department of Agriculture (Continued) WORLD AGRICULTURAL... inspection, copying, and indexing. 5 U.S.C. 552(a)(2) requires that certain materials be made available...

  2. 45 CFR 1703.404 - Copying and transcription charges.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Copying and transcription charges. 1703.404... Copying and transcription charges. (a) The Commission will charge fees for furnishing records at the rate of ten cents per page for photocopies and at the actual cost of transcription. When the...

  3. 40 CFR 716.30 - Submission of copies of studies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Submission of copies of studies. 716.30 Section 716.30 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.30 Submission of copies...

  4. 37 CFR 1.95 - Copies of exhibits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Models, Exhibits, Specimens § 1.95 Copies of exhibits. Copies of models or other physical exhibits will not ordinarily be furnished by the Office, and any model or exhibit in an application or patent shall not be taken from...

  5. 37 CFR 1.95 - Copies of exhibits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Models, Exhibits, Specimens § 1.95 Copies of exhibits. Copies of models or other physical exhibits will not ordinarily be furnished by the Office, and any model or exhibit in an application or patent shall not be taken from...

  6. 17. Photocopy of copy of drawing of Hangar 1301, dated ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopy of copy of drawing of Hangar 1301, dated June 15, 1944. Copy of drawing stored at 436 Civil Engineer Squadron, Design Management Element Cece, 600 8th Street, Dover Air Force Base, DE - Dover Air Force Base, Hangar No. 1301, Dover, Kent County, DE

  7. 18. Photocopy of copy of drawing of boiler plant and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of copy of drawing of boiler plant and shops building, dated June 15, 1944. Copy of drawing stored at 436 Civil Engineer Squadron, Design Management Element Cece, 600 8th Street, Dover AFB, DE - Dover Air Force Base, Hangar No. 1301, Dover, Kent County, DE

  8. 30 CFR 47.72 - Cost for copies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Cost for copies. 47.72 Section 47.72 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Making HazCom Information Available § 47.72 Cost for copies. (a) The operator...

  9. 30 CFR 47.72 - Cost for copies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Cost for copies. 47.72 Section 47.72 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Making HazCom Information Available § 47.72 Cost for copies. (a) The operator...

  10. 30 CFR 47.72 - Cost for copies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Cost for copies. 47.72 Section 47.72 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Making HazCom Information Available § 47.72 Cost for copies. (a) The operator...

  11. 48 CFR 6302.25 - Copies of papers (Rule 25).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Copies of papers (Rule 25). 6302.25 Section 6302.25 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.25 Copies of papers (Rule 25). When books, records, papers,...

  12. 48 CFR 6302.25 - Copies of papers (Rule 25).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Copies of papers (Rule 25). 6302.25 Section 6302.25 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.25 Copies of papers (Rule 25). When books, records, papers,...

  13. 48 CFR 6302.25 - Copies of papers (Rule 25).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Copies of papers (Rule 25). 6302.25 Section 6302.25 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.25 Copies of papers (Rule 25). When books, records, papers,...

  14. Perceiving the Impossible: How Individuals with Autism Copy Paradoxical Figures

    ERIC Educational Resources Information Center

    Sheppard, Elizabeth; Ropar, Danielle; Mitchell, Peter

    2009-01-01

    Mottron and colleagues found that individuals with autism were less affected by geometric impossibility than comparison participants on a copying task. The current experiment sought to determine whether a local perceptual style could account for this. Participants with and without autism copied possible and impossible geometric figures. Geometric…

  15. 36 CFR 1254.60 - What are NARA's copying services?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What are NARA's copying services? 1254.60 Section 1254.60 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED HISTORICAL MATERIALS Copying...

  16. 36 CFR 1254.64 - Will NARA certify copies?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Will NARA certify copies? 1254.64 Section 1254.64 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED HISTORICAL MATERIALS Copying...

  17. 36 CFR 1254.60 - What are NARA's copying services?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false What are NARA's copying services? 1254.60 Section 1254.60 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED HISTORICAL MATERIALS Copying...

  18. 36 CFR 1254.64 - Will NARA certify copies?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Will NARA certify copies? 1254.64 Section 1254.64 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED HISTORICAL MATERIALS Copying...

  19. 25 CFR 571.13 - Copies of audit reports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .../or reports as a result of the audit setting forth the results of each fiscal year. The submission... 25 Indians 2 2010-04-01 2010-04-01 false Copies of audit reports. 571.13 Section 571.13 Indians... MONITORING AND INVESTIGATIONS Audits § 571.13 Copies of audit reports. (a) Each tribe shall prepare...

  20. 47 CFR 3.25 - Number of copies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Application Procedures § 3.25 Number of copies. One original and one copy of FCC Form 44, “Application For Certification As An Accounting Authority” will be required. Only applications mailed to the Commission on official, Commission...

  1. 47 CFR 3.25 - Number of copies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Application Procedures § 3.25 Number of copies. One original and one copy of FCC Form 44, “Application For Certification As An Accounting Authority” will be required. Only applications mailed to the Commission on official, Commission...

  2. 9. Photographic copy of USRS design drawing, April 1906 (from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photographic copy of USRS design drawing, April 1906 (from duplicate copy on file at United States Bureau of Reclamation, Denver Service Center, Denver, Colorado). Main canal diversion weir from Salmon River - Salmon Creek Diversion Dam, Salmon Creek, Okanogan, Okanogan County, WA

  3. 7 CFR 3601.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Public inspection, copying, and indexing. 3601.2 Section 3601.2 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL AGRICULTURAL STATISTICS SERVICE, DEPARTMENT OF AGRICULTURE PUBLIC INFORMATION § 3601.2 Public inspection, copying,...

  4. 7 CFR 3601.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Public inspection, copying, and indexing. 3601.2 Section 3601.2 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL AGRICULTURAL STATISTICS SERVICE, DEPARTMENT OF AGRICULTURE PUBLIC INFORMATION § 3601.2 Public inspection, copying,...

  5. 7 CFR 3601.2 - Public inspection, copying, and indexing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Public inspection, copying, and indexing. 3601.2 Section 3601.2 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL AGRICULTURAL STATISTICS SERVICE, DEPARTMENT OF AGRICULTURE PUBLIC INFORMATION § 3601.2 Public inspection, copying,...

  6. 8. PHOTOGRAPHIC COPY OF AERIAL PHOTOGRAPH, DATED CA. 19201925, FORT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. PHOTOGRAPHIC COPY OF AERIAL PHOTOGRAPH, DATED CA. 1920-1925, FORT BLISS, ARROW POINTS TO 7TH CAVALRY CANTONMENT, COPY ON FILE IN THE ENVIRONMENTAL MANAGEMENT OFFICE, FORT BLISS - Fort Bliss, 7th Cavalry Buildings, U.S. Army Air Defence Artillery Center & Fort Bliss, El Paso, El Paso County, TX

  7. 6. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED MAY 15, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED MAY 15, 1919, 7TH CAVALRY CANTONMENT POST EXCHANGE, WAR DEPARTMENT, CONSTRUCTION DIVISION, PLAN No. 357, COPY ON FILE IN THE ENVIRONMENTAL MANAGEMENT OFFICE, FORT BLISS - Fort Bliss, 7th Cavalry Buildings, U.S. Army Air Defence Artillery Center & Fort Bliss, El Paso, El Paso County, TX

  8. 5. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED JUNE 14, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED JUNE 14, 1919, 7TH CAVALRY CANTONMENT MESS BUILDING, WAR DEPARTMENT, CONSTRUCTION DIVISION, PLAN No. 316A, COPY ON FILE IN THE ENVIRONMENTAL MANAGEMENT OFFICE, FORT BLISS - Fort Bliss, 7th Cavalry Buildings, U.S. Army Air Defence Artillery Center & Fort Bliss, El Paso, El Paso County, TX

  9. 4. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED MAY 13, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED MAY 13, 1919, DETACHMENT BARRACK WITHOUT MESS, WAR DEPARTMENT, CONSTRUCTION DIVISION, PLAN # 353, COPY ON FILE IN THE ENVIRONMENTAL MANAGEMENT OFFICE, FORT BLISS - Fort Bliss, 7th Cavalry Buildings, U.S. Army Air Defence Artillery Center & Fort Bliss, El Paso, El Paso County, TX

  10. 52. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. Photocopy of copy of original Officers' Duplex Quarters drawing by Copeland, 7 April 1932 (Original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University). Heating - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  11. 20. Photographic copy of the original construction drawing, 193031, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photographic copy of the original construction drawing, 1930-31, by Sverdrup and Parcel, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. Truss stress diagram, and plans of laterals and sway braces - Gasconade Bridge, Spanning Gasconade River at State Route 100, Gasconade, Gasconade County, MO

  12. 41. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. STRESS SHEET - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  13. 37. Photographic copy of the original construction drawing, 1934, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Photographic copy of the original construction drawing, 1934, by Sverdrup and Parcel, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department. Stress sheet, continuous span - Mark Twain Memorial Bridge, Spanning Mississippi River at US Route 36, Hannibal, Marion County, MO

  14. 53. Photocopy of copy of original Officers' Duplex Quarters drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photocopy of copy of original Officers' Duplex Quarters drawing by A.G.D., 7 April 1932 (original in possession of Veterans Administration, Wichita, Kansas, copy at Ablah Library, Wichita State University). Electrical - Veterans Administration Center, Officers Duplex Quarters, 5302 East Kellogg (Legal Address); 5500 East Kellogg (Common Address), Wichita, Sedgwick County, KS

  15. Vocal copying of individually distinctive signature whistles in bottlenose dolphins

    PubMed Central

    King, Stephanie L.; Sayigh, Laela S.; Wells, Randall S.; Fellner, Wendi; Janik, Vincent M.

    2013-01-01

    Vocal learning is relatively common in birds but less so in mammals. Sexual selection and individual or group recognition have been identified as major forces in its evolution. While important in the development of vocal displays, vocal learning also allows signal copying in social interactions. Such copying can function in addressing or labelling selected conspecifics. Most examples of addressing in non-humans come from bird song, where matching occurs in an aggressive context. However, in other animals, addressing with learned signals is very much an affiliative signal. We studied the function of vocal copying in a mammal that shows vocal learning as well as complex cognitive and social behaviour, the bottlenose dolphin (Tursiops truncatus). Copying occurred almost exclusively between close associates such as mother–calf pairs and male alliances during separation and was not followed by aggression. All copies were clearly recognizable as such because copiers consistently modified some acoustic parameters of a signal when copying it. We found no evidence for the use of copying in aggression or deception. This use of vocal copying is similar to its use in human language, where the maintenance of social bonds appears to be more important than the immediate defence of resources. PMID:23427174

  16. 6. Photo copy of photograph, (original owned by Mary Gaudineer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original owned by Mary Gaudineer, Beckley, WV, copy at National Forest Office, Elkins, WV), Don Gaudineer, 1934. CONSTRUCTION OF FERNOW EXPERIMENTAL FOREST BUNKHOUSE AND GARAGE. (see also historic photograph WV-237-13) - Parsons Nursery, Fernow Experimental Forest Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. 48. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    48. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS L9 TO L12 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  18. 54. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    54. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS U13 TO U16 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  19. 49. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS L13 TO L16 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  20. 55. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    55. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS U17 TO U20 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  1. 47. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    47. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS L5 TO L8 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  2. 51. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS L0, U2 TO U4, PORTAL AT U2 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  3. 50. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS L17 TO L20 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  4. 53. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS U9 TO U12 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  5. 52. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS U5 TO U8 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  6. 46. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, JOINTS L1 TO L4 - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  7. 47 CFR 78.67 - Copies of rules.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Copies of rules. 78.67 Section 78.67 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES CABLE TELEVISION RELAY SERVICE General Operating Requirements § 78.67 Copies of rules. The licensee of a CARS station shall...

  8. 47 CFR 78.67 - Copies of rules.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Copies of rules. 78.67 Section 78.67 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES CABLE TELEVISION RELAY SERVICE General Operating Requirements § 78.67 Copies of rules. The licensee of a CARS station shall...

  9. 47 CFR 78.67 - Copies of rules.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Copies of rules. 78.67 Section 78.67 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES CABLE TELEVISION RELAY SERVICE General Operating Requirements § 78.67 Copies of rules. The licensee of a CARS station shall...

  10. 47 CFR 78.67 - Copies of rules.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Copies of rules. 78.67 Section 78.67 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES CABLE TELEVISION RELAY SERVICE General Operating Requirements § 78.67 Copies of rules. The licensee of a CARS station shall...

  11. 47 CFR 78.67 - Copies of rules.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Copies of rules. 78.67 Section 78.67 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES CABLE TELEVISION RELAY SERVICE General Operating Requirements § 78.67 Copies of rules. The licensee of a CARS station shall...

  12. 44. Photographic copy of the original construction drawing, 192627, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. 671 FT. SPAN, SHOES - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

  13. 7 CFR 370.4 - Facilities for inspection and copying.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 370.4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH... copying. Facilities for public inspection and copying of the index and materials required to be made... Information Act Coordinator, Animal and Plant Health Inspection Service, Legislative and Public...

  14. Expression of COPI components during development of Drosophila melanogaster.

    PubMed

    Grieder, Nicole C; Kloter, Urs; Gehring, Walter J

    2005-12-01

    In a P{lArB} enhancer detector collection, a line was found that showed upregulated expression within centrally to posteriorly located germarial cysts. It was inserted in the gammaCOP locus on chromosome 3R. GammaCOP is a component of the COPI coatomer involved in membrane traffic. Most of the other known components of the COPI coatomer also showed higher expression in the posterior half of the germarium. Not only meiotic germline cysts but also migrating follicle cells upregulate the COPI subunits. During embryonic and larval development, the COPI subunits are expressed ubiquitously as expected for genes required for cell viability. In addition, they are strongly expressed in the salivary glands and the proventriculus. Whether tissue-specific transcriptional upregulation of COPI subunits is required for the reorganization of membranous compartments that are needed for the developmental processes that confer cyst polarity and follicle maturation will have to be addressed in a genetic study.

  15. Protocols for Copying and Proofreading in Template-Assisted Polymerization

    NASA Astrophysics Data System (ADS)

    Pigolotti, Simone; Sartori, Pablo

    2016-03-01

    We discuss how information encoded in a template polymer can be stochastically copied into a copy polymer. We consider four different stochastic copy protocols of increasing complexity, inspired by building blocks of the mRNA translation pathway. In the first protocol, monomer incorporation occurs in a single stochastic transition. We then move to a more elaborate protocol in which an intermediate step can be used for error correction. Finally, we discuss the operating regimes of two kinetic proofreading protocols: one in which proofreading acts from the final copying step, and one in which it acts from an intermediate step. We review known results for these models and, in some cases, extend them to analyze all possible combinations of energetic and kinetic discrimination. We show that, in each of these protocols, only a limited number of these combinations leads to an improvement of the overall copying accuracy.

  16. Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive

    PubMed Central

    Mishra, Sweta

    2016-01-01

    Chromosomal copy number changes are frequently associated with harmful consequences and are thought of as an underlying mechanism for the development of diseases. However, changes in copy number are observed during development and occur during normal biological processes. In this review, we highlight the causes and consequences of copy number changes in normal physiologic processes as well as cover their associations with cancer and acquired drug resistance. We discuss the permanent and transient nature of copy number gains and relate these observations to a new mechanism driving transient site-specific copy gains (TSSGs). Finally, we discuss implications of TSSGs in generating intratumoral heterogeneity and tumor evolution and how TSSGs can influence the therapeutic response in cancer. PMID:26755558

  17. Mitochondrial DNA Copy Number Is Associated with Breast Cancer Risk

    PubMed Central

    Thyagarajan, Bharat; Wang, Renwei; Nelson, Heather; Barcelo, Helene; Koh, Woon-Puay; Yuan, Jian-Min

    2013-01-01

    Mitochondrial DNA (mtDNA) copy number in peripheral blood is associated with increased risk of several cancers. However, data from prospective studies on mtDNA copy number and breast cancer risk are lacking. We evaluated the association between mtDNA copy number in peripheral blood and breast cancer risk in a nested case-control study of 183 breast cancer cases with pre-diagnostic blood samples and 529 individually matched controls among participants of the Singapore Chinese Health Study. The mtDNA copy number was measured using real time PCR. Conditional logistic regression analyses showed that there was an overall positive association between mtDNA copy number and breast cancer risk (Ptrend = 0.01). The elevated risk for higher mtDNA copy numbers was primarily seen for women with <3 years between blood draw and cancer diagnosis; ORs (95% CIs) for 2nd, 3rd, 4th, and 5th quintile of mtDNA copy number were 1.52 (0.61, 3.82), 2.52 (1.03, 6.12), 3.12 (1.31, 7.43), and 3.06 (1.25, 7.47), respectively, compared with the 1st quintile (Ptrend = 0.004). There was no association between mtDNA copy number and breast cancer risk among women who donated a blood sample ≥3 years before breast cancer diagnosis (Ptrend = 0.41). This study supports a prospective association between increased mtDNA copy number and breast cancer risk that is dependent on the time interval between blood collection and breast cancer diagnosis. Future studies are warranted to confirm these findings and to elucidate the biological role of mtDNA copy number in breast cancer risk. PMID:23776581

  18. Eclipse period of R1 plasmids during downshift from elevated copy number: Nonrandom selection of copies for replication.

    PubMed

    Olsson, Jan A; Berg, Otto; Nordström, Kurt; Dasgupta, Santanu

    2012-03-01

    The classical Meselson-Stahl density-shift method was used to study replication of pOU71, a runaway-replication derivative of plasmid R1 in Escherichia coli. The miniplasmid maintained the normal low copy number of R1 during steady growth at 30°C, but as growth temperatures were raised above 34°C, the copy number of the plasmid increased to higher levels, and at 42°C, it replicated without control in a runaway replication mode with lethal consequences for the host. The eclipse periods (minimum time between successive replication of the same DNA) of the plasmid shortened with rising copy numbers at increasing growth temperatures (Olsson et al., 2003). In this work, eclipse periods were measured during downshifts in copy number of pOU71 after it had replicated at 39 and 42°C, resulting in 7- and 50-fold higher than normal plasmid copy number per cell, respectively. Eclipse periods for plasmid replication, measured during copy number downshift, suggested that plasmid R1, normally selected randomly for replication, showed a bias such that a newly replicated DNA had a higher probability of replication compared to the bulk of the R1 population. However, even the unexpected nonrandom replication followed the copy number kinetics such that every generation, the plasmids underwent the normal inherited number of replication, n, independent of the actual number of plasmid copies in a newborn cell.

  19. Copy number variation in the horse genome.

    PubMed

    Ghosh, Sharmila; Qu, Zhipeng; Das, Pranab J; Fang, Erica; Juras, Rytis; Cothran, E Gus; McDonell, Sue; Kenney, Daniel G; Lear, Teri L; Adelson, David L; Chowdhary, Bhanu P; Raudsepp, Terje

    2014-10-01

    We constructed a 400K WG tiling oligoarray for the horse and applied it for the discovery of copy number variations (CNVs) in 38 normal horses of 16 diverse breeds, and the Przewalski horse. Probes on the array represented 18,763 autosomal and X-linked genes, and intergenic, sub-telomeric and chrY sequences. We identified 258 CNV regions (CNVRs) across all autosomes, chrX and chrUn, but not in chrY. CNVs comprised 1.3% of the horse genome with chr12 being most enriched. American Miniature horses had the highest and American Quarter Horses the lowest number of CNVs in relation to Thoroughbred reference. The Przewalski horse was similar to native ponies and draft breeds. The majority of CNVRs involved genes, while 20% were located in intergenic regions. Similar to previous studies in horses and other mammals, molecular functions of CNV-associated genes were predominantly in sensory perception, immunity and reproduction. The findings were integrated with previous studies to generate a composite genome-wide dataset of 1476 CNVRs. Of these, 301 CNVRs were shared between studies, while 1174 were novel and require further validation. Integrated data revealed that to date, 41 out of over 400 breeds of the domestic horse have been analyzed for CNVs, of which 11 new breeds were added in this study. Finally, the composite CNV dataset was applied in a pilot study for the discovery of CNVs in 6 horses with XY disorders of sexual development. A homozygous deletion involving AKR1C gene cluster in chr29 in two affected horses was considered possibly causative because of the known role of AKR1C genes in testicular androgen synthesis and sexual development. While the findings improve and integrate the knowledge of CNVs in horses, they also show that for effective discovery of variants of biomedical importance, more breeds and individuals need to be analyzed using comparable methodological approaches.

  20. Copy number variation in Thai population.

    PubMed

    Suktitipat, Bhoom; Naktang, Chaiwat; Mhuantong, Wuttichai; Tularak, Thitima; Artiwet, Paramita; Pasomsap, Ekawat; Jongjaroenprasert, Wallaya; Fuchareon, Suthat; Mahasirimongkol, Surakameth; Chantratita, Wasan; Yimwadsana, Boonsit; Charoensawan, Varodom; Jinawath, Natini

    2014-01-01

    Copy number variation (CNV) is a major genetic polymorphism contributing to genetic diversity and human evolution. Clinical application of CNVs for diagnostic purposes largely depends on sufficient population CNV data for accurate interpretation. CNVs from general population in currently available databases help classify CNVs of uncertain clinical significance, and benign CNVs. Earlier studies of CNV distribution in several populations worldwide showed that a significant fraction of CNVs are population specific. In this study, we characterized and analyzed CNVs in 3,017 unrelated Thai individuals genotyped with the Illumina Human610, Illumina HumanOmniexpress, or Illumina HapMap550v3 platform. We employed hidden Markov model and circular binary segmentation methods to identify CNVs, extracted 23,458 CNVs consistently identified by both algorithms, and cataloged these high confident CNVs into our publicly available Thai CNV database. Analysis of CNVs in the Thai population identified a median of eight autosomal CNVs per individual. Most CNVs (96.73%) did not overlap with any known chromosomal imbalance syndromes documented in the DECIPHER database. When compared with CNVs in the 11 HapMap3 populations, CNVs found in the Thai population shared several characteristics with CNVs characterized in HapMap3. Common CNVs in Thais had similar frequencies to those in the HapMap3 populations, and all high frequency CNVs (>20%) found in Thai individuals could also be identified in HapMap3. The majorities of CNVs discovered in the Thai population, however, were of low frequency, or uniquely identified in Thais. When performing hierarchical clustering using CNV frequencies, the CNV data were clustered into Africans, Europeans, and Asians, in line with the clustering performed with single nucleotide polymorphism (SNP) data. As CNV data are specific to origin of population, our population-specific reference database will serve as a valuable addition to the existing resources for

  1. Converting hard copy documents for electronic dissemination

    SciTech Connect

    Hoffman, F.

    1994-12-31

    Since the advent of computer systems, the goal of a paperless office, and even a paperless society, has been pursued. While the normal paper flow in an organization is far from totally automated, particularly for items requiring signatures or authorizations, electronic information dissemination is becoming an almost simple task. The reasons for providing on-line documents are many and include faster and easier access for everyone, elimination of printing costs, reduction of wasted shelf and desk space, and the security of having a centrally-located, always up-to-date document. New computer software even provides the user with the ability to annotate documents and to have bookmarks so that the old scribbled-in and dog-eared manual can be replaced without loosing this `customizability`. Moreover, new hypermedia capabilities mean that documents can be read in a non-linear fashion and can include color figures and photographs, audio, and even animation sequences, capabilities which exceed those of paper. The proliferation of network-based information servers, coupled with the growth of the Internet, has enticed academic, governmental, and even commercial organizations to provide increasing numbers of documents and data bases in electronic form via the network, not just to internal staff, but to the public as well. Much of this information, which includes everything from mundane company procedures to spiffy marketing brochures, was previously published only in hard copy. Converting existing documents to electronic form and producing only electronic versions of new documents poses some interesting challenges to the maintainer or author.

  2. Copy Number Profiling of Brazilian Astrocytomas

    PubMed Central

    Bidinotto, Lucas Tadeu; Torrieri, Raul; Mackay, Alan; Almeida, Gisele Caravina; Viana-Pereira, Marta; Cruvinel-Carloni, Adriana; Spina, Maria Luisa; Campanella, Nathalia Cristina; Pereira de Menezes, Weder; Clara, Carlos Afonso; Becker, Aline Paixão; Jones, Chris; Reis, Rui Manuel

    2016-01-01

    Copy number alterations (CNA) are one of the driving mechanisms of glioma tumorigenesis, and are currently used as important biomarkers in the routine setting. Therefore, we performed CNA profiling of 65 astrocytomas of distinct malignant grades (WHO grade I–IV) of Brazilian origin, using array-CGH and microsatellite instability analysis (MSI), and investigated their correlation with TERT and IDH1 mutational status and clinico-pathological features. Furthermore, in silico analysis using the Oncomine database was performed to validate our findings and extend the findings to gene expression level. We found that the number of genomic alterations increases in accordance with glioma grade. In glioblastomas (GBM), the most common alterations were gene amplifications (PDGFRA, KIT, KDR, EGFR, and MET) and deletions (CDKN2A and PTEN). Log-rank analysis correlated EGFR amplification and/or chr7 gain with better survival of the patients. MSI was observed in 11% of GBMs. A total of 69% of GBMs presented TERT mutation, whereas IDH1 mutation was most frequent in diffuse (85.7%) and anaplastic (100%) astrocytomas. The combination of 1p19q deletion and TERT and IDH1 mutational status separated tumor groups that showed distinct age of diagnosis and outcome. In silico validation pointed to less explored genes that may be worthy of future investigation, such as CDK2, DMRTA1, and MTAP. Herein, using an extensive integrated analysis, we indicated potentially important genes, not extensively studied in gliomas, that could be further explored to assess their biological and clinical impact in astrocytomas. PMID:27172220

  3. Copy Number Variation in Familial Parkinson Disease

    PubMed Central

    Pankratz, Nathan; Dumitriu, Alexandra; Hetrick, Kurt N.; Sun, Mei; Latourelle, Jeanne C.; Wilk, Jemma B.; Halter, Cheryl; Doheny, Kimberly F.; Gusella, James F.; Nichols, William C.; Myers, Richard H.; Foroud, Tatiana; DeStefano, Anita L.

    2011-01-01

    Copy number variants (CNVs) are known to cause Mendelian forms of Parkinson disease (PD), most notably in SNCA and PARK2. PARK2 has a recessive mode of inheritance; however, recent evidence demonstrates that a single CNV in PARK2 (but not a single missense mutation) may increase risk for PD. We recently performed a genome-wide association study for PD that excluded individuals known to have either a LRRK2 mutation or two PARK2 mutations. Data from the Illumina370Duo arrays were re-clustered using only white individuals with high quality intensity data, and CNV calls were made using two algorithms, PennCNV and QuantiSNP. After quality assessment, the final sample included 816 cases and 856 controls. Results varied between the two CNV calling algorithms for many regions, including the PARK2 locus (genome-wide p = 0.04 for PennCNV and p = 0.13 for QuantiSNP). However, there was consistent evidence with both algorithms for two novel genes, USP32 and DOCK5 (empirical, genome-wide p-values<0.001). PARK2 CNVs tended to be larger, and all instances that were molecularly tested were validated. In contrast, the CNVs in both novel loci were smaller and failed to replicate using real-time PCR, MLPA, and gel electrophoresis. The DOCK5 variation is more akin to a VNTR than a typical CNV and the association is likely caused by artifact due to DNA source. DNA for all the cases was derived from whole blood, while the DNA for all controls was derived from lymphoblast cell lines. The USP32 locus contains many SNPs with low minor allele frequency leading to a loss of heterozygosity that may have been spuriously interpreted by the CNV calling algorithms as support for a deletion. Thus, only the CNVs within the PARK2 locus could be molecularly validated and associated with PD susceptibility. PMID:21829596

  4. On Multiplying Negative Numbers.

    ERIC Educational Resources Information Center

    Crowley, Mary L.; Dunn, Kenneth A.

    1985-01-01

    Comments on the history of negative numbers, some methods that can be used to introduce the multiplication of negative numbers to students, and an explanation of why the product of two negative numbers is a positive number are included. (MNS)

  5. Mitochondrial DNA copy number in peripheral blood and melanoma risk.

    PubMed

    Shen, Jie; Gopalakrishnan, Vancheswaran; Lee, Jeffrey E; Fang, Shenying; Zhao, Hua

    2015-01-01

    Mitochondrial DNA (mtDNA) copy number in peripheral blood has been suggested as risk modifier in various types of cancer. However, its influence on melanoma risk is unclear. We evaluated the association between mtDNA copy number in peripheral blood and melanoma risk in 500 melanoma cases and 500 healthy controls from an ongoing melanoma study. The mtDNA copy number was measured using real-time polymerase chain reaction. Overall, mean mtDNA copy number was significantly higher in cases than in controls (1.15 vs 0.99, P<0.001). Increased mtDNA copy number was associated with a 1.45-fold increased risk of melanoma (95% confidence interval: 1.12-1.97). Significant joint effects between mtDNA copy number and variables related to pigmentation and history of sunlight exposure were observed. This study supports an association between increased mtDNA copy number and melanoma risk that is independent on the known melanoma risk factors (pigmentation and history of sunlight exposure).

  6. 22 CFR 92.79 - Procuring copies of foreign public documents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... foreign officials copies of birth, death, and marriage certificates, or copies of other public records... RELATED SERVICES Copying, Recording, Translating and Procuring Documents § 92.79 Procuring copies of... pay for copies of or extracts from foreign public records obtained at the request of private...

  7. Fabrication of reflection gratings by contact copying of amplitude holographic gratings on a metal surface

    NASA Astrophysics Data System (ADS)

    Madjidi-Zolbanine, Habib; Hodjat-Zadeh, A.

    1995-04-01

    This paper describes the contact copying of amplitude transmission holographic gratings. Master gratings (MG) are written in silver halide sensitized gelatine. A smooth and flat sheet is coated with a layer of negative photoresist constituted from a combination of polyvinyl alcohol, ammonium dichromate and Arabic gum, then the MG is put in contact with the metal surface and exposed by a mercury lamp. After processing with deionized water at (35 degree(s)C), a reflection grating is obtained. For a MG with 117 l/mm of spatial frequency and 10% of diffraction efficiency (DE), we have obtained a DE of 12%.

  8. Copy number gain of VCX, X-linked multi-copy gene, leads to cell proliferation and apoptosis during spermatogenesis

    PubMed Central

    Huang, Zhenyao; Zhang, Yan; Zhou, Ran; Song, Ling; Ling, Xiufeng; Hu, Zhibin; Miao, Dengshun; Shen, Hongbing; Xia, Yankai; Wang, Xinru; Lu, Chuncheng

    2016-01-01

    Male factor infertility affects one-sixth of couples worldwide, and non-obstructive azoospermia (NOA) is one of the most severe forms. In recent years there has been increasing evidence to implicate the participation of X chromosome in the process of spermatogenesis. To uncover the roles of X-linked multi-copy genes in spermatogenesis, we performed systematic analysis of X-linked gene copy number variations (CNVs) and Y chromosome haplogrouping in 447 idiopathic NOA patients and 485 healthy controls. Interestingly, the frequency of individuals with abnormal level copy of Variable charge, X-linked (VCX) was significantly different between cases and controls after multiple test correction (p = 5.10 × 10−5). To discriminate the effect of gain/loss copies in these genes, we analyzed the frequency of X-linked multi-copy genes in subjects among subdivided groups. Our results demonstrated that individuals with increased copy numbers of Nuclear RNA export factor 2 (NXF2) (p = 9.21 × 10−8) and VCX (p = 1.97 × 10−4) conferred the risk of NOA. In vitro analysis demonstrated that increasing copy number of VCX could upregulate the gene expression and regulate cell proliferation and apoptosis. Our study establishes a robust association between the VCX CNVs and NOA risk. PMID:27705943

  9. Finding-specific display presets for computed radiography soft-copy reading.

    PubMed

    Andriole, K P; Gould, R G; Webb, W R

    1999-05-01

    Much work has been done to optimize the display of cross-sectional modality imaging examinations for soft-copy reading (i.e., window/level tissue presets, and format presentations such as tile and stack modes, four-on-one, nine-on-one, etc). Less attention has been paid to the display of digital forms of the conventional projection x-ray. The purpose of this study is to assess the utility of providing presets for computed radiography (CR) soft-copy display, based not on the window/level settings, but on processing applied to the image optimized for visualization of specific findings, pathologies, etc (i.e., pneumothorax, tumor, tube location). It is felt that digital display of CR images based on finding-specific processing presets has the potential to: speed reading of digital projection x-ray examinations on soft copy; improve diagnostic efficacy; standardize display across examination type, clinical scenario, important key findings, and significant negatives; facilitate image comparison; and improve confidence in and acceptance of soft-copy reading. Clinical chest images are acquired using an Agfa-Gevaert (Mortsel, Belgium) ADC 70 CR scanner and Fuji (Stamford, CT) 9000 and AC2 CR scanners. Those demonstrating pertinent findings are transferred over the clinical picture archiving and communications system (PACS) network to a research image processing station (Agfa PS5000), where the optimal image-processing settings per finding, pathologic category, etc, are developed in conjunction with a thoracic radiologist, by manipulating the multiscale image contrast amplification (Agfa MUSICA) algorithm parameters. Soft-copy display of images processed with finding-specific settings are compared with the standard default image presentation for 50 cases of each category. Comparison is scored using a 5-point scale with the positive scale denoting the standard presentation is preferred over the finding-specific processing, the negative scale denoting the finding

  10. Copy number variation and evolution in humans and chimpanzees

    PubMed Central

    Perry, George H.; Yang, Fengtang; Marques-Bonet, Tomas; Murphy, Carly; Fitzgerald, Tomas; Lee, Arthur S.; Hyland, Courtney; Stone, Anne C.; Hurles, Matthew E.; Tyler-Smith, Chris; Eichler, Evan E.; Carter, Nigel P.; Lee, Charles; Redon, Richard

    2008-01-01

    Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and provide the raw material for gene duplication and gene family expansion. However, our understanding of their evolutionary significance remains limited. We performed comparative genomic hybridization on a single human microarray platform to identify CNVs among the genomes of 30 humans and 30 chimpanzees as well as fixed copy number differences between species. We found that human and chimpanzee CNVs occur in orthologous genomic regions far more often than expected by chance and are strongly associated with the presence of highly homologous intrachromosomal segmental duplications. By adapting population genetic analyses for use with copy number data, we identified functional categories of genes that have likely evolved under purifying or positive selection for copy number changes. In particular, duplications and deletions of genes with inflammatory response and cell proliferation functions may have been fixed by positive selection and involved in the adaptive phenotypic differentiation of humans and chimpanzees. PMID:18775914

  11. 5. Photographic copy of photograph (Source: Salt River Project Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photographic copy of photograph (Source: Salt River Project Archives, Tempe, Lubken collection, #R-273) Transformer house under construction. View looking north. July 1, 1908. - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

  12. 10. Photographic copy of drawing dated January 22, 1908 (Source: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photographic copy of drawing dated January 22, 1908 (Source: Salt River Project) General plans, index to detail plans and sections, transformer house - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

  13. 11. Photographic copy of drawing dated February 17, 1908 (Source: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of drawing dated February 17, 1908 (Source: Salt River Project) Transformer building, first floor plan and sections (Transformer floor) - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

  14. 8. Photographic copy of photograph (Source: Salt River Project Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photographic copy of photograph (Source: Salt River Project Archives, Tempe, Box 8040, File 29) View of transformer house looking north. No date. CA. 1920. - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

  15. 6. Photographic copy of photograph (Source: Salt River Project Archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photographic copy of photograph (Source: Salt River Project Archives, Tempe, Lubken collection, #R-295) Transformer house under construction. View looking north. October 5, 1908. - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

  16. 9. Photographic copy of drawing dated June 24, 1908 (Source: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photographic copy of drawing dated June 24, 1908 (Source: Salt River Project) Transformer house, general drawing - Theodore Roosevelt Dam, Transformer House, Salt River, Tortilla Flat, Maricopa County, AZ

  17. 118. Photographic copy of historic photo, April 5, 1932 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    118. Photographic copy of historic photo, April 5, 1932 (original print filed in Record Group 115, National Archives, Washington, D.C.). INVAR VOLUME METER, PANEL NO. 3, OWYHEE DAM. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  18. 120. Photographic copy of historic photo, April 5, 1932 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    120. Photographic copy of historic photo, April 5, 1932 (original print filed in Record Group 115, National Archives, Washington, D.C.). INVAR VOLUME METER IN PANEL NO. 3, OWYHEE DAM. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  19. 119. Photographic copy of historic photo, April 5, 1932 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    119. Photographic copy of historic photo, April 5, 1932 (original print filed in Record Group 115, National Archives, Washington, D.C.). INSTALLING INVAR METER IN PANEL NO. 4, OWYHEE DAM. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  20. 21. Photographic copy of photograph, c. 1926 (print located at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photographic copy of photograph, c. 1926 (print located at Lockmaster's House, Starved Rock Lock and Dam, near Utica, Illinois). EXCAVATION FOR LOCK. - Starved Rock Locks & Dam, Illinois Waterway River mile 231, Peru, La Salle County, IL

  1. 14. Photo copy of drawing, April 3, 1952, GREEN'S LEDGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photo copy of drawing, April 3, 1952, GREEN'S LEDGE L/S MODERNIZATION. Drawing no. NY 1517, U.S. Coast Guard Civil Engineering Unit, Warwick, Rhode Island. - Green's Ledge Lighthouse, Long Island Sound, Norwalk, Fairfield County, CT

  2. 12. Photo copy of drawing, May 5, 1930. PENFIELD REEF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photo copy of drawing, May 5, 1930. PENFIELD REEF L/S MODERNIZATION. Drawing no. NY-1393, U.S. Coast GUard Civil Engineering Unit, Warwick, Rhode Island. - Penfield Reef Lighthouse, Long Island Sound, Bridgeport, Fairfield County, CT

  3. Intron analyses reveal multiple calmodulin copies in Littorina.

    PubMed

    Simpson, R J; Wilding, C S; Grahame, J

    2005-04-01

    Intron 3 and the flanking exons of the calmodulin gene have been amplified, cloned, and sequenced from 18 members of the gastropod genus Littorina. From the 48 sequences, at least five different gene copies have been identified and their functionality characterized using a strategy based upon the potential protein product predicted from flanking exon data. The functionality analyses suggest that four of the genes code for functional copies of calmodulin. All five copies have been identified across a wide range of littorinid species although not ubiquitously. Using this novel approach based on intron sequences, we have identified an unprecedented number of potential calmodulin copies in Littorina, exceeding that reported for any other invertebrate. This suggests a higher number of, and more ancient, gene duplications than previously detected in a single genus.

  4. 3. COPY OF A PHOTOGRAPH OF THE CATARACT MILLS, NEWBURGH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. COPY OF A PHOTOGRAPH OF THE CATARACT MILLS, NEWBURGH, OHIO. Date unknown. Photographer: Berni Rich, Score Photographers, September 1986 - Alexander's Grist Mill, Lock 37 on Ohio & Erie Canal, South of Cleveland, Valley View, Cuyahoga County, OH

  5. Photographic copy of reproduced photograph dated 1942. Exterior view, west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of reproduced photograph dated 1942. Exterior view, west elevation. Building camouflaged during World War II. - Grand Central Air Terminal, 1310 Air Way, Glendale, Los Angeles County, CA

  6. PHOTOGRAPHIC COPY OF PHOTOGRAPH (FROM GIFFORD PINCHOT NATIONAL FOREST COLLECTION, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PHOTOGRAPHIC COPY OF PHOTOGRAPH (FROM GIFFORD PINCHOT NATIONAL FOREST COLLECTION, COPYRIGHT COLUMBIA NATIONAL FOREST. PHOTOGRAPHER UNKNOWN, DECEMBER 13, 1935. TROUT CREEK DAM FISHWAY UNDER CONSTRUCTION - Trout Creek Dam, River Mile 1.8 on Trout Creek, Carson, Skamania County, WA

  7. 1. Historic American Buildings Survey Copied by Alex Bush, Photographer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Copied by Alex Bush, Photographer, March 15, 1935 OLD COLLEGE PAMPHLET. NOT COPYRIGHTED. FRONT AND SIDE VIEW S.E. (BEFORE ALTERATION). - Marion Female Seminary, Monroe & Centreville Streets, Marion, Perry County, AL

  8. 3. Historic American Buildings Survey (Copy) Nathaniel R. Ewan, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey (Copy) Nathaniel R. Ewan, Photographer November 15, 1937 INTERIOR - STRONG BOX From anniversary booklet printed by Farmers Trust Co. - not copyrighted. - Farmer's Trust Company Bank Building, 21 Mill Street, Mount Holly, Burlington County, NJ

  9. 1. Historic American Buildings Survey COPIED E. W. Russell, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey COPIED - E. W. Russell, Photographer, August 31, 1936 75TH ANNIVERSARY YEARBOOK (NOT COPYRIGHT) - VIEW OF ORIGINAL BUILDING - Spring Hill College, Original Building, Old Shell Road, Spring Hill, Mobile County, AL

  10. 3. Historic American Buildings Survey, Copied by Survey Photographer. Taken ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey, Copied by Survey Photographer. Taken before 1868. (f) Ext- Old Photo-- General view from N.W. - India Wharf Stores, 306-308 Atlantic Avenue, Boston, Suffolk County, MA

  11. 1. Historic American Buildings Survey Copied by Survey, Photographer, Old ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Copied by Survey, Photographer, Old Photo before 1880 (a) Ext-General view from Southwest. - Governor Thomas Prence House, King's Highway (U.S. Route 6), Eastham, Barnstable County, MA

  12. 2. Historic American Buildings Survey, Copied by Survey Photographer (e) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey, Copied by Survey Photographer (e) Ext-Old Photograph- Gen View North and East Elevations, (before 1868) - India Wharf Stores, 306-308 Atlantic Avenue, Boston, Suffolk County, MA

  13. Hotspots for copy number variation in chimpanzees and humans

    PubMed Central

    Perry, George H.; Tchinda, Joelle; McGrath, Sean D.; Zhang, Junjun; Picker, Simon R.; Cáceres, Angela M.; Iafrate, A. John; Tyler-Smith, Chris; Scherer, Stephen W.; Eichler, Evan E.; Stone, Anne C.; Lee, Charles

    2006-01-01

    Copy number variation is surprisingly common among humans and can be involved in phenotypic diversity and variable susceptibility to complex diseases, but little is known of the extent of copy number variation in nonhuman primates. We have used two array-based comparative genomic hybridization platforms to identify a total of 355 copy number variants (CNVs) in the genomes of 20 wild-born chimpanzees (Pan troglodytes) and have compared the identified chimpanzee CNVs to known human CNVs from previous studies. Many CNVs were observed in the corresponding regions in both chimpanzees and humans; especially those CNVs of higher frequency. Strikingly, these loci are enriched 20-fold for ancestral segmental duplications, which may facilitate CNV formation through nonallelic homologous recombination mechanisms. Therefore, some of these regions may be unstable “hotspots” for the genesis of copy number variation, with recurrent duplications and deletions occurring across and within species. PMID:16702545

  14. 11. Photographic copy of construction drawing, dated May 10, 1922, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of construction drawing, dated May 10, 1922, in possession of SCIP, Coolidge, AZ. GENERAL PLAN - San Carlos Irrigation Project, Ashurst-Hayden Dam, Gila River, T4S R11E S7, Coolidge, Pinal County, AZ

  15. 17. Photographic copy of construction drawing, dated June, 1921, in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photographic copy of construction drawing, dated June, 1921, in possession of SCIP, Coolidge, AZ. REGULATOR GATE ASSEMBLY - San Carlos Irrigation Project, Ashurst-Hayden Dam, Gila River, T4S R11E S7, Coolidge, Pinal County, AZ

  16. 140. Photograph of a copy of the original shop drawing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    140. Photograph of a copy of the original shop drawing for the lumber ports added in 1899. Original located at San Francisco Maritime National Historical Park. - Ship BALCLUTHA, 2905 Hyde Street Pier, San Francisco, San Francisco County, CA

  17. 33. Historic American Buildings Survey COPY OF PRELIMINARY STUDY FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. Historic American Buildings Survey COPY OF PRELIMINARY STUDY FOR HEALY BUILDING, c. 1876 (COURTESY OF THE COMMISSION OF FINE ARTS) - Georgetown University, Healy Building, Thirty-seventh & O Streets, Northwest, Washington, District of Columbia, DC

  18. 13. Photographic copy of photograph (March 23, 1909, original print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photographic copy of photograph (March 23, 1909, original print in possession of Montana Power Company, Butte, Montana). 'DRIVING THE LAST #85 RAIL' - Milltown Dam, Clark Fork River, 6 miles upstream from Missoula, Milltown, Missoula County, MT

  19. 19. COPY OF ENGRAVING OF 'WROUGHT IRON ARCH TRUSS BRIDGE,' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. COPY OF ENGRAVING OF 'WROUGHT IRON ARCH TRUSS BRIDGE,' PAT. DEC. 10, 1867 BY OHIO BRIDGE COMPANY, CLEVELAND, OHIO. (COURTESY OF OHIO HISTORICAL SOCIETY ARCHIVES, COLUMBUS, OHIO) - Tioronda Bridge, South Avenue spanning Fishkill Creek, Beacon, Dutchess County, NY

  20. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). PASTING JEWEL BLANKS, PREPARATION FOR DRILLING. - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  1. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). FINAL INSPECTION - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  2. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). OLIVING - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  3. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). DRILLING - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  4. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). MACHINE SHOP - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  5. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). LARGE HOLE-OPENING - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  6. Remote hard copy. Volume 3. Systems programming manual

    SciTech Connect

    Simons, R.W.

    1980-03-01

    The software used to operate and maintain the remote hard copy is described. All operating software that runs in the NOVA minicomputers is covered as are various utility and diagnostic programs used for creating and checking this software. 2 figures.

  7. 9. Historic American Buildings Survey Copy of c. 1894 Photograph ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Historic American Buildings Survey Copy of c. 1894 Photograph of Excavation (from Private Collection of Leroy O. King, Georgetown) - Capital Traction Company Union Station, 3600 M Street Northwest, Washington, District of Columbia, DC

  8. 10. Historic American Buildings Survey Copy of c. 1894 Photograph ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey Copy of c. 1894 Photograph of Excavation (from Private Collection of Leroy O. King, Georgetown) - Capital Traction Company Union Station, 3600 M Street Northwest, Washington, District of Columbia, DC

  9. 2. Historic American Buildings Survey Max R. Nippell, Photographer (Copied ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Max R. Nippell, Photographer (Copied by Frank O. Branzetti) (b) EXT.-SIDE, LOOKING NORTHWEST - Town Hall, State Routes 41 & 17, South Egremont, Berkshire County, MA

  10. 30. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, 'tractor with cultivator operating'), photographer unknown, ca. 1938. VIEW SOUTHEAST, CULTIVATING SEEDLING TRANSPLANTS. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  11. 28. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, August 1939. D. A. OLIVER WITH A TRANSPLANT BOARD. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  12. 37. Photo copy of map, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Photo copy of map, (original in Forest Service Office, Elkins, WV, 'Blister Rust Survey Map), 1930. PARSONS NURSERY SITE PLAN - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  13. 3. West and south elevations. Joseph Hill, photographer, copied from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. West and south elevations. Joseph Hill, photographer, copied from photo lent by Evelyn S. Craig. August 1936. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  14. 2. Historic American Buildings Survey Copied from an old print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Copied from an old print by Joseph Hill. OLD STORE AND POST OFFICE, FROM 'HISTORIC BISHOP HILL'- EVELYN S. CRAIG - Jansonist Colony, Colony Store & Post Office, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  15. 2. West and south elevation. Copied from an old print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West and south elevation. Copied from an old print by Joseph Hill, lent to survey by Evelyn S. Craig. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  16. 5. Historic American Buildings Survey, COPY OF AN OLD VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey, COPY OF AN OLD VIEW IN THE PHILADELPHIANA COLLECTION, LOGAN SQUARE BRANCH, FREE LIBRARY OF PHILADELPHIA, SHOWING BRIDGE BEFORE THE ROADWAY WAS WIDENED. - Chestnut Street Bridge, Schuykill River, Chestnut Street vicinity, Philadelphia, Philadelphia County, PA

  17. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama), 1916. Side elevation - Balboa School, Northeast end of El Prado, Balboa, Former Panama Canal Zone, CZ

  18. 8. OVERVIEW OF THE TOWNSITE, LOOKING WEST Photographic copy of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. OVERVIEW OF THE TOWNSITE, LOOKING WEST Photographic copy of historic photograph. No date. Original print is located in Lemhi County Historical Museum, Salmon, Idaho. Photographer is unknown. - Leesburg Townsite, Napias Creek, Salmon, Lemhi County, ID

  19. 9. OVERVIEW OF THE TOWNSITE, LOOKING EAST Photographic copy of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. OVERVIEW OF THE TOWNSITE, LOOKING EAST Photographic copy of historic photograph. Taken prior to 1929. Original print is located in Lemhi County Historical Museum, Salmon, Idaho. Photographer is unknown. - Leesburg Townsite, Napias Creek, Salmon, Lemhi County, ID

  20. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). WEST ELEVATION - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  1. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). SOUTH ELEVATION, TRANSVERSE SECTION, NORTH ELEVATION - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  2. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). SECOND FLOOR PLAN - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  3. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). EAST ELEVATION - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  4. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). BIN TOWER SECTIONS AND PLAN - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  5. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). DETAIL OF MAIN STAIR AND MISCELLANEOUS PLANS - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  6. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). FIRST FLOOR PLAN - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  7. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). EXTERIOR ENTRANCE AND WINDOW BAY - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  8. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). BASEMENT PLAN - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  9. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). EXTERIOR MASONRY DETAILS - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  10. Photographic copy of architectural drawing, 1921 (original located at University ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing, 1921 (original located at University of Minnesota Facilities Management Office, Minneapolis). SUB BASEMENT PLAN - Mines Experiment Station, University of Minnesota, Twin Cities Campus, 56 East River Road, Minneapolis, Hennepin County, MN

  11. Photographic copy of photograph, photographer unknown, 1908 (original print located ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 1908 (original print located at National Archives and Records Administration, Denver, Colorado). "HANDLING ROCK - BOISE RIVER DIVERSION DAM." - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  12. Photographic copy of photograph, photographer unknown, 1908 (original print located ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 1908 (original print located at National Archives and Records Administration, Denver, Colorado). "CONSTRUCTION - BOISE RIVER DIVERSION DAM." - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  13. 18. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. GLENARM PLACE (NORTHWESTERN) SIDE - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  14. 82. Photographic copy of original construction drawing dated October 1909 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    82. Photographic copy of original construction drawing dated October 1909 (from microfiche located at Bureau of Reclamation, Denver, Colorado) SOUTH SIDE BOISE DIVISION: WEST END OUTLET FROM UPPER EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  15. 28. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. ROOF PLAN - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  16. Photographic copy of photograph, photographer unknown, 1908 (original print located ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 1908 (original print located at National Archives and Records Administration, Denver, Colorado). "CONSTRUCTION - BOISE RIVER DAM" WITH FOOT BRIDGE IN FOREGROUND - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  17. Photographic copy of photograph, photographer unknown, 23 May 1912 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 23 May 1912 (original print located at National Archives and Records Administration, Denver, Colorado). "SWITCHBOARD IN POWER PLANT AT DIVERSION DAM" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  18. 17. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. FRONT (SIXTEENTH STREET) - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  19. 21. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. BASEMENT PLAN - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  20. Photographic copy of photograph, photographer unknown, 17 April 1912 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 17 April 1912 (original print located at National Archives and Records Administration, Denver, Colorado). "POWER PLANT CONSTRUCTION AT DIVERSION DAM" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  1. 27. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. FIFTH FLOOR - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  2. 26. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. FOURTH FLOOR - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  3. 25. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. THIRD FLOOR - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  4. Photographic copy of photograph, photographer unknown, 20 March 1913 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 20 March 1913 (original print located at National Archives and Records Administration, Denver, Colorado). "ROLLING DAM AT DIVERSION DAM" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  5. 78. Photographic copy of original construction drawing dated October 1909 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    78. Photographic copy of original construction drawing dated October 1909 (from microfiche located at Bureau of Reclamation, Denver, Colorado) SOUTH SIDE BOISE DIVISION: OUTLET FROM LOWER EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  6. Photographic copy of photograph, photographer unknown, 20 March 1913 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 20 March 1913 (original print located at National Archives and Records Administration, Denver, Colorado). "ROLLING DAM IN SPILLWAY AT DIVERSION DAM" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  7. 81. Photographic copy of original construction drawing dated October 1909 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    81. Photographic copy of original construction drawing dated October 1909 (from microfiche located at Bureau of Reclamation, Denver, Colorado) SOUTH SIDE BOISE DIVISION: EAST END OUTLET FROM UPPER EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  8. Photographic copy of photograph, photographer unknown, 20 March 1912 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 20 March 1912 (original print located at National Archives and Records Administration, Denver, Colorado). "INTERIOR OF POWER HOUSE BEFORE COMPLETION" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  9. 20. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. ALLEY (SOUTHEASTERN) SIDE - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  10. 19. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. REAR (SOUTHWESTERN SIDE) - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  11. 77. Photographic copy of original construction drawing dated October 1909 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    77. Photographic copy of original construction drawing dated October 1909 (from microfiche located at Bureau of Reclamation, Denver, Colorado) SOUTH SIDE BOISE DIVISION: LOWER DEER FLAT EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  12. 80. Photographic copy of original construction drawing dated October 1909 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    80. Photographic copy of original construction drawing dated October 1909 (from microfiche located at Bureau of Reclamation, Denver, Colorado) SOUTH SIDE BOISE DIVISION: UPPER DEER FLAT EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  13. 24. Photographic copy of the original architectural drawing (1906) in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Photographic copy of the original architectural drawing (1906) in the possession of the Colorado Historical Society, Denver, Colorado. SECOND FLOOR - Empire Building, 430 Sixteenth Street, South Corner of Sixteenth Street & Glenarm Place, Denver, Denver County, CO

  14. Photographic copy of photograph, photographer unknown, 20 March 1912 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 20 March 1912 (original print located at National Archives and Records Administration, Denver, Colorado). "DIVERSION WORKS AND POWER HOUSE CONSTRUCTION" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  15. Photographic copy of photograph, photographer unknown, 23 May 1912 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, photographer unknown, 23 May 1912 (original print located at National Archives and Records Administration, Denver, Colorado). "GENERATORS IN POWER PLANT; DIVERSION DAM" - Boise Project, Boise River Diversion Dam, Across Boise River, Boise, Ada County, ID

  16. 22. Photographic copy of photograph, circa 1928, photographer unknown (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photographic copy of photograph, circa 1928, photographer unknown (original in Rundell Library, Rochester, New York) AUDITORIUM AND STAGE DECORATED FOR POLITICAL CONVENTION, VIEW FROM BALCONY LOOKING SOUTHWEST - New York State Arsenal, 75 Woodbury Boulevard, Rochester, Monroe County, NY

  17. 43. Photographic copy of original construction plan (Wabasha Str. Bridge, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. Photographic copy of original construction plan (Wabasha Str. Bridge, 65 ft Space, floorbeams, 1888); typical details of floorbeams, first span - Wabasha Street Bridge, Spanning Mississippi River at Wabasha Street, Saint Paul, Ramsey County, MN

  18. 117. Photographic copy of historic photo, December 27, 1930 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    117. Photographic copy of historic photo, December 27, 1930 (original print filed in Record Group 115, National Archives, Washington, D.C.). OWYHEE DAM SLUICE GATES BEING SET INTO PLACE. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  19. 117. NORTH FACADE, WEST END Copy photograph of photogrammetric plate ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    117. NORTH FACADE, WEST END Copy photograph of photogrammetric plate LC-HABS-GS05-T-2626-205R. - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  20. 27 CFR 25.301 - Photographic copies of records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Records and Reports § 25.301 Photographic copies of... it were the original record. All provisions of law and regulations applicable to the original...

  1. 27 CFR 25.301 - Photographic copies of records.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Records and Reports § 25.301 Photographic copies of... it were the original record. All provisions of law and regulations applicable to the original...

  2. 27 CFR 25.301 - Photographic copies of records.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Records and Reports § 25.301 Photographic copies of... it were the original record. All provisions of law and regulations applicable to the original...

  3. 27 CFR 25.301 - Photographic copies of records.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Records and Reports § 25.301 Photographic copies of... it were the original record. All provisions of law and regulations applicable to the original...

  4. 27 CFR 25.301 - Photographic copies of records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Records and Reports § 25.301 Photographic copies of... it were the original record. All provisions of law and regulations applicable to the original...

  5. Human copy number variation and complex genetic disease.

    PubMed

    Girirajan, Santhosh; Campbell, Catarina D; Eichler, Evan E

    2011-01-01

    Copy number variants (CNVs) play an important role in human disease and population diversity. Advancements in technology have allowed for the analysis of CNVs in thousands of individuals with disease in addition to thousands of controls. These studies have identified rare CNVs associated with neuropsychiatric diseases such as autism, schizophrenia, and intellectual disability. In addition, copy number polymorphisms (CNPs) are present at higher frequencies in the population, show high diversity in copy number, sequence, and structure, and have been associated with multiple phenotypes, primarily related to immune or environmental response. However, the landscape of copy number variation still remains largely unexplored, especially for smaller CNVs and those embedded within complex regions of the human genome. An integrated approach including characterization of single nucleotide variants and CNVs in a large number of individuals with disease and normal genomes holds the promise of thoroughly elucidating the genetic basis of human disease and diversity.

  6. Molecular methods for genotyping complex copy number polymorphisms.

    PubMed

    Cantsilieris, Stuart; Baird, Paul N; White, Stefan J

    2013-02-01

    Genome structural variation shows remarkable complexity with respect to copy number, sequence content and distribution. While the discovery of copy number polymorphisms (CNP) has increased exponentially in recent years, the transition from discovery to genotyping has proved challenging, particularly for CNPs embedded in complex regions of the genome. CNPs that are collectively common in the population and possess a dynamic range of copy numbers have proved the most difficult to genotype in association studies. This is in some part due to technical limitations of genotyping assays and the sequence properties of the genomic region being analyzed. Here we describe in detail the basis of a number of molecular techniques used to genotype complex CNPs, compare and contrast these approaches for determination of multi-allelic copy number, and discuss the potential application of these techniques in genetic studies.

  7. Evolution vs the number of gene copies per primitive cell.

    PubMed

    Koch, A L

    1984-01-01

    Computer simulations are presented of the rate at which an advantageous mutant would displace the prototype in a replicating system without an accurate segregation mechanism. If the number of gene copies in the system is indefinitely large, Darwinian evolution is essentially stopped because there is no coupling of phenotype with genotype, i.e., there is no growth advantage to the advantageous gene relative to the prototype and therefore no "survival of the fittest." The inhibition of evolution due to a number of gene copies less than 100 would have been not insurmountable. Although the presence of multiple copies would have allowed replacement by an advantageous mutant, it provided a way for the primitive cell to conserve less immediately useful genes that could evolve into different or more effective genes. This possibility was lost as accurate segregation mechanisms evolved and cells with few copies of each gene, such as modern procaryotes, arose.

  8. 6. Photographic copy of photograph (date unknown, original print in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photographic copy of photograph (date unknown, original print in the possession of the Wisconsin Veterans Museums). COTTAGES, INCLUDING 'J.P. McPHERSON POST NO. 27 CAFE GENEVA'. - Wisconsin Home for Veterans, King, Waupaca County, WI

  9. 12. Historic American Buildings Survey, COPY, UTAH HERITAGE FOUNDATION (INTERIOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey, COPY, UTAH HERITAGE FOUNDATION (INTERIOR PHOTO LATE 1880'S). - Zion's Cooperative Mercantile Institution, 15 South Main Street, Salt Lake City, Salt Lake County, UT

  10. 17 CFR 200.52 - Copies of the Canons.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.52 Copies of the Canons. The Canons have been distributed to employees of the Commission. In addition, executive and professional...

  11. 5. PHOTOGRAPHIC COPY OF ORIGINAL DRAWINGS, ELECTRIC AIR AND HEATING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. PHOTOGRAPHIC COPY OF ORIGINAL DRAWINGS, ELECTRIC AIR AND HEATING UNIT, PLAN AND ELEVATION - Wyoming Air National Guard Base, Electric, Air & Heating Plant, Cheyenne Airport, Cheyenne, Laramie County, WY

  12. 4. Photographic copy of the original construction drawing, 1927, by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photographic copy of the original construction drawing, 1927, by Missouri State Highway Department. Stress diagrams, floor framing plans, and details of trusses - Doxie Creek Bridge, Spanning Doxie Creek at State Route 5, Forest Green, Chariton County, MO

  13. 159. COPY OF A CONSTRUCTION PHOTOGRAPH OF A DETAIL OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    159. COPY OF A CONSTRUCTION PHOTOGRAPH OF A DETAIL OF CONCRETE FRAMEWORK AT THE LOWER THREE FLOORS OF THE SOUTHEAST ELEVATION, CENTRAL PAVILION, TAKEN OCTOBER 7, 1905 - Blenheim Hotel, Ohio Avenue & Boardwalk, Atlantic City, Atlantic County, NJ

  14. 157. Copy of Louis Rosenberg Etching (original in the Tower ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    157. Copy of Louis Rosenberg Etching (original in the Tower City Development Office) TERMINAL TOWER UNDER CONSTRUCTION, STEEL FRAMEWORK OF THE SOUTHWEST WING, VIEW WEST TO EAST - Terminal Tower Building, Cleveland Union Terminal, 50 Public Square, Cleveland, Cuyahoga County, OH

  15. 162. COPY OF A CONSTRUCTION PHOTOGRAPH OF A DETAIL OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    162. COPY OF A CONSTRUCTION PHOTOGRAPH OF A DETAIL OF CONCRETE FRAMEWORK AT THE LOWER THREE FLOORS OF THE SOUTHEAST ELEVATION, CENTRAL PAVILION, TAKEN NOVEMBER 1, 1905 - Blenheim Hotel, Ohio Avenue & Boardwalk, Atlantic City, Atlantic County, NJ

  16. 176. Photographic copy of original construction drawing dated February 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    176. Photographic copy of original construction drawing dated February 10, 1933 (from Record Group 115, Denver Branch of the National Archives, Denver). OWYHEE DAM; LOCATION OF THERMOMETER GROUPS. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  17. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. Ground floor plan. - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  18. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. Exterior Details - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  19. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1941. First floor plan - Fort Amador, Four Apartments, Van Hook Place, Panama City, Former Panama Canal Zone, CZ

  20. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. Second floor plan. - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  1. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. Exterior details - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  2. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Rodman, Republic or Panama), 1940. Elevations. - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  3. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. First floor plan. - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  4. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940) Toilet plans - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  5. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. Details of toilets - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  6. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1941. Basement floor plan. - Fort Amador, Four Apartments, Van Hook Place, Panama City, Former Panama Canal Zone, CZ

  7. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1940. Sections - Fort Amador, Administration Building, Rear Admiral Nimitz Circle, Panama City, Former Panama Canal Zone, CZ

  8. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Real Property Office, Naval Base Rodman, Republic of Panama), 1941. Elevation and section - Fort Amador, Four Apartments, Van Hook Place, Panama City, Former Panama Canal Zone, CZ

  9. 11. COPY OF 1970 AERIAL PHOTOGRAPH OF LORING AIR FORCE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. COPY OF 1970 AERIAL PHOTOGRAPH OF LORING AIR FORCE BASE. PHOTOGRAPH LOCATED AT AIR FORCE BASE CONVERSION AGENCY, LORING AIR FORCE BASE, MAINE. - Loring Air Force Base, Airfield, Central portion of base, Limestone, Aroostook County, ME

  10. 17. Photographic copy of photograph (April 22, 1909, original print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photographic copy of photograph (April 22, 1909, original print in possession of Montana Power Company, Butte, Montana). 'PLACING RIP RAP' - Milltown Dam, Clark Fork River, 6 miles upstream from Missoula, Milltown, Missoula County, MT

  11. 2. COPY OF MAP DATED 121073, OF THE CLEVELAND DISTRICT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. COPY OF MAP DATED 12-10-73, OF THE CLEVELAND DISTRICT STEEL PLANT, REPUBLIC STEEL CORPORATION. MAP COURTESY REPUBLIC STEEL. - Corrigan, McKinney Steel Company, 3100 East Forty-fifth Street, Cleveland, Cuyahoga County, OH

  12. 47 CFR 74.1269 - Copies of rules.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1269 Copies of rules. The licensee or permittee of a...

  13. 47 CFR 74.1269 - Copies of rules.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES FM Broadcast Translator Stations and FM Broadcast Booster Stations § 74.1269 Copies of rules. The licensee or permittee of a...

  14. 126. Photographic copy of historic photo, April 19, 1932 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    126. Photographic copy of historic photo, April 19, 1932 (original print filed in Record Group 115, National Archives, Washington, D.C.). OWYHEE DAM-RESISTANCE RECORDING EQUIPMENT. - Owyhee Dam, Across Owyhee River, Nyssa, Malheur County, OR

  15. 7. Photograph is copy of historic photo (original print located ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photograph is copy of historic photo (original print located in Ogden Air Logistics Center, Hill Air Force Base, Utah). Photographer unknown. - Ogden Arsenal, Primer Loading Building for 37mm Shell Loading, 7726 North Carolina Way, Layton, Davis County, UT

  16. 16. Photographic copy of drawing, dated September 1924, in possession ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photographic copy of drawing, dated September 1924, in possession of San Carlos Irrigation Project. United States Indian Service, Irrigation. PIMA LATERAL HEADWORKS, RADIAL GATES - San Carlos Irrigation Project, Pima Lateral, Main Canal at Sacaton Dam, Coolidge, Pinal County, AZ

  17. 5. Photographic copy of historic photograph (from Wind Cave National ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photographic copy of historic photograph (from Wind Cave National Park), photographer unknown, date unknown. Route 87, Beaver Creek Bridge, elevation. - Beaver Creek Bridge, Hot Springs, Fall River County, SD

  18. 10. Photographic copy of microfilm of construction drawing, dated February ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photographic copy of microfilm of construction drawing, dated February 1915, in the possession of the Yellowstone County Surveyor, Yellowstone County Courthouse, Billings, Montana. - Duck Creek Bridge, Spanning Yellowstone River on Route 329, Southwest of Billings, Billings, Yellowstone County, MT

  19. 11. Photographic copy of microfilm of construction drawing, dated February ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photographic copy of microfilm of construction drawing, dated February 1915, in the possession of the Yellowstone County Surveyor, Yellowstone County Courthouse, Billings, Montana. - Duck Creek Bridge, Spanning Yellowstone River on Route 329, Southwest of Billings, Billings, Yellowstone County, MT

  20. 1. Historic American Buildings Survey, Copy, Photographer unknown 1900 (a) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey, Copy, Photographer unknown 1900 (a) Old Photo showing Kilns about 1900 (from original print found at site) - Charcoal Kilns, Valley Road, Pelham, Hampshire County, MA

  1. 2. Historic American Buildings Survey, COPY OF DRAWING PREPARED BY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey, COPY OF DRAWING PREPARED BY M.B. LOCKWOOD IN 1843, IN OFFICE OF RECORDER OF DEEDS, PROVIDENCE. - Clark & Nightingale Block, 247-259 South Main Street, Providence, Providence County, RI

  2. 7. Historic American Buildings Survey DETAIL SHOWING MOUNT CLARE Copy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey DETAIL SHOWING MOUNT CLARE Copy of Lithograph, titled 'Bird's Eye View of Baltimore' Edward Sachse & Co., 1869 - Mount Clare, Bayard & South Monroe Streets, Carroll Park, Baltimore, Independent City, MD

  3. 1. Historic American Buildings Survey Copied by Joseph Hill from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Copied by Joseph Hill from an old photograph loaned by Alice Snyder, Galena, Illinois. SOUTH EAST ELEVATION - Grace Episcopal Church, South Prospect Street, Galena, Jo Daviess County, IL

  4. 2. Historic American Buildings Survey Copied by Joseph Hill from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Copied by Joseph Hill from photograph loaned by the Illinois Bell Telephone Co. SOUTH EAST ELEVATION - Grace Episcopal Church, South Prospect Street, Galena, Jo Daviess County, IL

  5. Detection of Copy-Rotate-Move Forgery Using Zernike Moments

    NASA Astrophysics Data System (ADS)

    Ryu, Seung-Jin; Lee, Min-Jeong; Lee, Heung-Kyu

    As forgeries have become popular, the importance of forgery detection is much increased. Copy-move forgery, one of the most commonly used methods, copies a part of the image and pastes it into another part of the the image. In this paper, we propose a detection method of copy-move forgery that localizes duplicated regions using Zernike moments. Since the magnitude of Zernike moments is algebraically invariant against rotation, the proposed method can detect a forged region even though it is rotated. Our scheme is also resilient to the intentional distortions such as additive white Gaussian noise, JPEG compression, and blurring. Experimental results demonstrate that the proposed scheme is appropriate to identify the forged region by copy-rotate-move forgery.

  6. 57. Photographic copy of historic photo, May 1908 (original print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Photographic copy of historic photo, May 1908 (original print filed in Record Group 115, National Archives, Washington, D.C.). UPPER DEER FLAT EMBANKMENT; CAMP AND BUILDINGS. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  7. 68. Photographic copy of historic photo, June, 1912 (original print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    68. Photographic copy of historic photo, June, 1912 (original print filed in Record Group 115, National Archives, Washington, D.C.). INLET GATES, DEER FLAT RESERVOIR. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  8. 64. Photographic copy of historic photo, July 1908 (original print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    64. Photographic copy of historic photo, July 1908 (original print filed in Record Group 115, National Archives, Washington, D.C.). TEAM MOVING TRACK ON UPPER DEER FLAT EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  9. 54. Photographic copy of historic photo, January 16, 1909 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    54. Photographic copy of historic photo, January 16, 1909 (original print filed in Record Group 115, National Archives, Washington, D.C.). LOWER DEER FLAT EMBANKMENT. - Boise Project, Deer Flat Embankments, Lake Lowell, Nampa, Canyon County, ID

  10. 27. Photographic copy of undated photo; Photographer unknown; Original owned ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photographic copy of undated photo; Photographer unknown; Original owned by Waterloo Community Development Board, Waterloo, Iowa; SPLITTING CATTLE CARCASSES WITH RECIPROCATING SAW - Rath Packing Company, Beef Killing Building, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

  11. 19. INTERIOR: ARCH AND CORBELED VAULT NEAR FRONT Copy photograph ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. INTERIOR: ARCH AND CORBELED VAULT NEAR FRONT Copy photograph of photogrammetric plate LC-HABS-GS07-1116-113L. - Provident Life & Trust Company Bank, 407-409 Chestnut Street, Philadelphia, Philadelphia County, PA

  12. 6. Historic American Buildings Survey, Arthur C. Haskell, Photographer; COPY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey, Arthur C. Haskell, Photographer; COPY OF VIEW BELONGING RO MR. FAXON, OF QUINCY. (f) Ext- Photo of full size model of old car. - Granite Railway, Pine Hill Quarry to Neponset River, Quincy, Norfolk County, MA

  13. 14. Power copy of drawing, August 21, 1915. POWER PLANT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Power copy of drawing, August 21, 1915. POWER PLANT EXTENSION, GENERAL PLANS. Drawing No. 4415, Facilities Engineering, Army Materials Technology Laboratory, Watertown, Massachusetts. - Watertown Arsenal, Building No. 60, Arsenal Street, Watertown, Middlesex County, MA

  14. 12. Photo copy of drawing, Feb. 5, 1912. ARRANGEMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photo copy of drawing, Feb. 5, 1912. ARRANGEMENT OF POWER HOUSE EQUIPMENT. Drawing No. 9053. Facilities Engineering, Army Materials Technology Laboratory, Watertown, Massachusetts. - Watertown Arsenal, Building No. 60, Arsenal Street, Watertown, Middlesex County, MA

  15. 15. Power copy of drawing, August 21, 1915. POWER PLANT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Power copy of drawing, August 21, 1915. POWER PLANT EXTENSION, GENERAL PLANS. Drawing No. PA-A-36692, Facilities Engineering, Army Materials Technology Laboratory, Watertown, Massachusetts. - Watertown Arsenal, Building No. 60, Arsenal Street, Watertown, Middlesex County, MA

  16. 13. Photo copy of drawing, Feb. 5, 1912. ARRANGEMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photo copy of drawing, Feb. 5, 1912. ARRANGEMENT OF POWER HOUSE EQUIPMENT. Drawing No. 9053. Facilities Engineering, Army Materials Technology Laboratory, Watertown, Massachusetts. - Watertown Arsenal, Building No. 60, Arsenal Street, Watertown, Middlesex County, MA

  17. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama). Left side elevation. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  18. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama). Rear elevation. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  19. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama). Longitudinal section. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  20. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama). Second floor plan. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  1. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama). Front elevation. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  2. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama). First floor plan. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  3. Photographic copy of architectural drawing (original drawing located at the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of architectural drawing (original drawing located at the Panama Canal Commission Headquarters Building, Department of Engineering Vault, Balboa Heights, Republic of Panama), Right side elevation. - Quarry Heights, Officers' Quarters, Parkinson Lane, Balboa, Former Panama Canal Zone, CZ

  4. 7. Historic American Buildings Survey COPY OF CA. 1888 PHOTO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey COPY OF CA. 1888 PHOTO LOOKING NORTH FROM COURTHOUSE TOWER, SHOWING MARKET HOUSE (RIGHT) AND TOMLINSON HALL (LEFT) - Indianapolis City Market, 222 East Market Street, Indianapolis, Marion County, IN

  5. 15. Photographic copy of floor plan, not dated, in possession ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photographic copy of floor plan, not dated, in possession of Selfridge Base Museum, Mt. Clemens, Michigan. - Selfridge Field, Building No. 1050, Northwest corner of Doolittle Avenue & D Street; Harrison Township, Mount Clemens, Macomb County, MI

  6. 14. Photo copy of photograph (location of original print unknown) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photo copy of photograph (location of original print unknown) c.1932, photographer unknown Historic view of bridge - Bridge at Mouth of Rogue River, Spanning Rogue River on Oregon Coast Highway, Gold Beach, Curry County, OR

  7. 40 CFR 716.30 - Submission of copies of studies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Submission of copies of studies. 716... studies. (a)(1) Except as provided in §§ 716.5, 716.20, and 716.50, persons must send to EPA copies of any health and safety studies in their possession for the substances or mixtures listed in § 716.120....

  8. Using DMA for copying performance counter data to memory

    DOEpatents

    Gara, Alan; Salapura, Valentina; Wisniewski, Robert W

    2013-12-31

    A device for copying performance counter data includes hardware path that connects a direct memory access (DMA) unit to a plurality of hardware performance counters and a memory device. Software prepares an injection packet for the DMA unit to perform copying, while the software can perform other tasks. In one aspect, the software that prepares the injection packet runs on a processing core other than the core that gathers the hardware performance data.

  9. Using DMA for copying performance counter data to memory

    DOEpatents

    Gara, Alan; Salapura, Valentina; Wisniewski, Robert W.

    2012-09-25

    A device for copying performance counter data includes hardware path that connects a direct memory access (DMA) unit to a plurality of hardware performance counters and a memory device. Software prepares an injection packet for the DMA unit to perform copying, while the software can perform other tasks. In one aspect, the software that prepares the injection packet runs on a processing core other than the core that gathers the hardware performance counter data.

  10. The Value of Patch-Choice Copying in Fruit Flies

    PubMed Central

    Golden, Shane; Dukas, Reuven

    2014-01-01

    Many animals copy the choices of others but the functional and mechanistic explanations for copying are still not fully resolved. We relied on novel behavioral protocols to quantify the value of patch-choice copying in fruit flies. In a titration experiment, we quantified how much nutritional value females were willing to trade for laying eggs on patches already occupied by larvae (social patches). Females were highly sensitive to nutritional quality, which was positively associated with their offspring success. Females, however, perceived social, low-nutrition patches (33% of the nutrients) as equally valuable as non-social, high-nutrition ones (100% of the nutrients). In follow-up experiments, we could not, however, either find informational benefits from copying others or detect what females' offspring may gain from developing with older larvae. Because patch-choice copying in fruit flies is a robust phenomenon in spite of potential costs due to competition, we suggest that it is beneficial in natural settings, where fruit flies encounter complex dynamics of microbial communities, which include, in addition to the preferred yeast species they feed on, numerous harmful fungi and bacteria. We suggest that microbial ecology underlies many cases of copying in nature. PMID:25375776

  11. Physiological Functions of the COPI Complex in Higher Plants.

    PubMed

    Ahn, Hee-Kyung; Kang, Yong Won; Lim, Hye Min; Hwang, Inhwan; Pai, Hyun-Sook

    2015-10-01

    COPI vesicles are essential to the retrograde transport of proteins in the early secretory pathway. The COPI coatomer complex consists of seven subunits, termed α-, β-, β'-, γ-, δ-, ε-, and ζ-COP, in yeast and mammals. Plant genomes have homologs of these subunits, but the essentiality of their cellular functions has hampered the functional characterization of the subunit genes in plants. Here we have employed virus-induced gene silencing (VIGS) and dexamethasone (DEX)-inducible RNAi of the COPI subunit genes to study the in vivo functions of the COPI coatomer complex in plants. The β'-, γ-, and δ-COP subunits localized to the Golgi as GFP-fusion proteins and interacted with each other in the Golgi. Silencing of β'-, γ-, and δ-COP by VIGS resulted in growth arrest and acute plant death in Nicotiana benthamiana, with the affected leaf cells exhibiting morphological markers of programmed cell death. Depletion of the COPI subunits resulted in disruption of the Golgi structure and accumulation of autolysosome-like structures in earlier stages of gene silencing. In tobacco BY-2 cells, DEX-inducible RNAi of β'-COP caused aberrant cell plate formation during cytokinesis. Collectively, these results suggest that COPI vesicles are essential to plant growth and survival by maintaining the Golgi apparatus and modulating cell plate formation.

  12. 18. View to southwest. Detail, bearing shoe, upstream side of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. View to southwest. Detail, bearing shoe, upstream side of east pier. Copy negative made from 35mm color transparency made with with 135mm lens by John Snyder, due to lack of sufficiently long lens for 4x5 camera. - South Fork Trinity River Bridge, State Highway 299 spanning South Fork Trinity River, Salyer, Trinity County, CA

  13. Copy number variation at the GL7 locus contributes to grain size diversity in rice.

    PubMed

    Wang, Yuexing; Xiong, Guosheng; Hu, Jiang; Jiang, Liang; Yu, Hong; Xu, Jie; Fang, Yunxia; Zeng, Longjun; Xu, Erbo; Xu, Jing; Ye, Weijun; Meng, Xiangbing; Liu, Ruifang; Chen, Hongqi; Jing, Yanhui; Wang, Yonghong; Zhu, Xudong; Li, Jiayang; Qian, Qian

    2015-08-01

    Copy number variants (CNVs) are associated with changes in gene expression levels and contribute to various adaptive traits. Here we show that a CNV at the Grain Length on Chromosome 7 (GL7) locus contributes to grain size diversity in rice (Oryza sativa L.). GL7 encodes a protein homologous to Arabidopsis thaliana LONGIFOLIA proteins, which regulate longitudinal cell elongation. Tandem duplication of a 17.1-kb segment at the GL7 locus leads to upregulation of GL7 and downregulation of its nearby negative regulator, resulting in an increase in grain length and improvement of grain appearance quality. Sequence analysis indicates that allelic variants of GL7 and its negative regulator are associated with grain size diversity and that the CNV at the GL7 locus was selected for and used in breeding. Our work suggests that pyramiding beneficial alleles of GL7 and other yield- and quality-related genes may improve the breeding of elite rice varieties.

  14. Copy number variations exploration of multiple genes in Graves’ disease

    PubMed Central

    Song, Rong-hua; Shao, Xiao-qing; Li, Ling; Wang, Wen; Zhang, Jin-an

    2017-01-01

    Abstract Background: Few previous published papers reported copy number variations of genes could affect the predisposition of Graves’ disease (GD). Herein, the aim of this study was to explore the association between copy number variations (CNV) profile and GD. Methods: The preliminary copy number microarray used to screen copy number variant genes was performed in 6 GD patients. Five CNV candidate genes (CFH, CFHR1, KIAA0125, UGT2B15, and UGT2B17) were then validated in an independent set of samples (50 GD patients and 50 matched healthy ones) by the Accucopy assay method. The CNV of the other 2 genes TRY6 and CCL3L1 was investigated in 144 GD patients and 144 healthy volunteers by the definitive genotyping technique using the Taqman quantitative polymerase-chain-reaction (Taqman qPCR). TRY6 gene-associated single nucleotide polymorphism (SNP), rs13230029, was genotyped by the PCR-ligase detection reaction (LDR) in 675 GD patients and 898 healthy controls. Results: There were no correlation of the gene copy number (GCN) of CFH, CFHR1, KIAA0125, UGT2B15, and UGT2B17 with GD. In comparison with that of controls, the GCN distribution of TRY6 and CCL3L1 in GD patients did not show significantly differ (P > 0.05). Furthermore, TRY6-related polymorphism (rs13230029) showed no difference between GD patients and controls. No correlation was found between CNV or SNP genotype and clinical phenotypes. Generally, there were no link of the copy numbers of several genes, including CFH, CFHR1, KIAA0125, UGT2B15, UGT2B17, TRY6, and CCL3L1 to GD. Conclusion: Our results clearly indicated that the copy number variations of multiple genes, namely CFH, CFHR1, KIAA0125, UGT2B15, UGT2B17, TRY6, and CCL3L1, were not associated with the development of GD. PMID:28121931

  15. Culture-negative endocarditis

    MedlinePlus

    ... inflammation of the lining of one or more heart valves, but no endocarditis-causing germs can be found ... the heart, where they can settle on damaged heart valves. Alternative Names Endocarditis (culture-negative) Images Culture-negative ...

  16. Negative ion generator

    DOEpatents

    Stinnett, Regan W.

    1984-01-01

    A negative ion generator is formed from a magnetically insulated transmission line having a coating of graphite on the cathode for producing negative ions and a plurality of apertures on the opposed anode for the release of negative ions. Magnetic insulation keeps electrons from flowing from the cathode to the anode. A transverse magnetic field removes electrons which do escape through the apertures from the trajectory of the negative ions.

  17. Negative ion generator

    DOEpatents

    Stinnett, R.W.

    1984-05-08

    A negative ion generator is formed from a magnetically insulated transmission line having a coating of graphite on the cathode for producing negative ions and a plurality of apertures on the opposed anode for the release of negative ions. Magnetic insulation keeps electrons from flowing from the cathode to the anode. A transverse magnetic field removes electrons which do escape through the apertures from the trajectory of the negative ions. 8 figs.

  18. Sentential Negation in English

    ERIC Educational Resources Information Center

    Mowarin, Macaulay

    2009-01-01

    This paper undertakes a detailed analysis of sentential negation in the English language with Chomsky's Government-Binding theory of Transformational Grammar as theoretical model. It distinguishes between constituent and sentential negation in English. The essay identifies the exact position of Negation phrase in an English clause structure. It…

  19. Mitochondrial DNA Copy Number in Sleep Duration Discordant Monozygotic Twins

    PubMed Central

    Wrede, Joanna E.; Mengel-From, Jonas; Buchwald, Dedra; Vitiello, Michael V.; Bamshad, Michael; Noonan, Carolyn; Christiansen, Lene; Christensen, Kaare; Watson, Nathaniel F.

    2015-01-01

    Study Objectives: Mitochondrial DNA (mtDNA) copy number is an important component of mitochondrial function and varies with age, disease, and environmental factors. We aimed to determine whether mtDNA copy number varies with habitual differences in sleep duration within pairs of monozygotic twins. Setting: Academic clinical research center. Participants: 15 sleep duration discordant monozygotic twin pairs (30 twins, 80% female; mean age 42.1 years [SD 15.0]). Design: Sleep duration was phenotyped with wrist actigraphy. Each twin pair included a “normal” (7–9 h/24) and “short” (< 7 h/24) sleeping twin. Fasting peripheral blood leukocyte DNA was assessed for mtDNA copy number via the n-fold difference between qPCR measured mtDNA and nuclear DNA creating an mtDNA measure without absolute units. We used generalized estimating equation linear regression models accounting for the correlated data structure to assess within-pair effects of sleep duration on mtDNA copy number. Measurements and Results: Mean within-pair sleep duration difference per 24 hours was 94.3 minutes (SD 62.6 min). We found reduced sleep duration (β = 0.06; 95% CI 0.004, 0.12; P < 0.05) and sleep efficiency (β = 0.51; 95% CI 0.06, 0.95; P < 0.05) were significantly associated with reduced mtDNA copy number within twin pairs. Thus every 1-minute decrease in actigraphy-defined sleep duration was associated with a decrease in mtDNA copy number of 0.06. Likewise, a 1% decrease in actigraphy-defined sleep efficiency was associated with a decrease in mtDNA copy number of 0.51. Conclusions: Reduced sleep duration and sleep efficiency were associated with reduced mitochondrial DNA copy number in sleep duration discordant monozygotic twins offering a potential mechanism whereby short sleep impairs health and longevity through mitochondrial stress. Citation: Wrede JE, Mengel-From J, Buchwald D, Vitiello MV, Bamshad M, Noonan C, Christiansen L, Christensen K, Watson NF. Mitochondrial DNA copy number

  20. Reconstructing DNA copy number by joint segmentation of multiple sequences

    PubMed Central

    2012-01-01

    Background Variations in DNA copy number carry information on the modalities of genome evolution and mis-regulation of DNA replication in cancer cells. Their study can help localize tumor suppressor genes, distinguish different populations of cancerous cells, and identify genomic variations responsible for disease phenotypes. A number of different high throughput technologies can be used to identify copy number variable sites, and the literature documents multiple effective algorithms. We focus here on the specific problem of detecting regions where variation in copy number is relatively common in the sample at hand. This problem encompasses the cases of copy number polymorphisms, related samples, technical replicates, and cancerous sub-populations from the same individual. Results We present a segmentation method named generalized fused lasso (GFL) to reconstruct copy number variant regions. GFL is based on penalized estimation and is capable of processing multiple signals jointly. Our approach is computationally very attractive and leads to sensitivity and specificity levels comparable to those of state-of-the-art specialized methodologies. We illustrate its applicability with simulated and real data sets. Conclusions The flexibility of our framework makes it applicable to data obtained with a wide range of technology. Its versatility and speed make GFL particularly useful in the initial screening stages of large data sets. PMID:22897923