Science.gov

Sample records for 5-8 making plans

  1. Homemaking--Family Living. Curriculum Planning Guidelines. Level I-II. Middle School, Grades 5-8. Reprint 1978. Home Economics Education, [No. 1].

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Occupational Education Curriculum Development.

    This curriculum guide for Levels I and II home economics teachers in New York State provides guidelines for developing instructional program content for grades 5-8. An introductory section describes the design of the homemaking-family living curriculum; presents procedures for utilizing modules in planning instruction with an example of plans for…

  2. HWMA/RCRA CLOSURE PLAN FOR THE MATERIALS TEST REACTOR WING (TRA-604) LABORATORY COMPONENTS VOLUNTARY CONSENT ORDER ACTION PLAN VCO-5.8 D REVISION2

    SciTech Connect

    KIRK WINTERHOLLER

    2008-02-25

    This Hazardous Waste Management Act/Resource Conservation and Recovery Act closure plan was developed for the laboratory components of the Test Reactor Area Catch Tank System (TRA-630) that are located in the Materials Test Reactor Wing (TRA-604) at the Reactor Technology Complex, Idaho National Laboratory Site, to meet a further milestone established under Voluntary Consent Order Action Plan VCO-5.8.d. The TRA-604 laboratory components addressed in this closure plan were deferred from the TRA-630 Catch Tank System closure plan due to ongoing laboratory operations in the areas requiring closure actions. The TRA-604 laboratory components include the TRA-604 laboratory warm wastewater drain piping, undersink drains, subheaders, and the east TRA-604 laboratory drain header. Potentially contaminated surfaces located beneath the TRA-604 laboratory warm wastewater drain piping and beneath the island sinks located in Laboratories 126 and 128 (located in TRA-661) are also addressed in this closure plan. The TRA-604 laboratory components will be closed in accordance with the interim status requirements of the Hazardous Waste Management Act/Resource Conservation and Recovery Act as implemented by the Idaho Administrative Procedures Act 58.01.05.009 and 40 Code of Federal Regulations 265, Subparts G and J. This closure plan presents the closure performance standards and the methods for achieving those standards.

  3. Planning Makes College Possible.

    ERIC Educational Resources Information Center

    Belmont, Jean

    Written by a college financial aid administrator, this booklet is intended to help parents of younger children plan and prepare for the financial aspects of college education. After an introductory chapter, Chapter II lists current and projected (year 2000) costs at the most expensive colleges and at New York City colleges. Chapter III presents…

  4. Environmental planning and decision making

    SciTech Connect

    Ortolano, L.

    1984-01-01

    Environmental planning is a multidisciplinary field encompassing biology, engineering, geography, the earth sciences, and landscape architecture among other subjects. This book was written in textbook format to provide an introduction to the field. It is suitable for students at all levels, professionals, and general readers interested in the quality of the environment. It includes a list of key concepts and terms for each chapter, references for further study, discussion questions, and a subject index. Contents: Residuals management. Environmental impact assessment. Land use and the environment. Index.

  5. Planning and Decision Making for Care Transitions

    PubMed Central

    Sörensen, Silvia; Mak, Wingyun; Pinquart, Martin

    2015-01-01

    The need to plan for future health care and residential adjustments increases with age, growing frailty, and restrictions in coverage of long-term care and will continue to grow with population aging. Older adults’ lack of financial preparation for health care costs, insufficient knowledge about available options, and inadequate communication about care-related values has become an increasing public health challenge. This chapter describes a model of Preparation for Future Care (PFC), which encompasses different levels and domains of planning. Research about the extent to which planning is helpful in navigating care transitions is reviewed, and barriers and facilitators of planning including individual, familial, cultural, and national long-term care policy factors are discussed. Planning in the context of dementia and practical approaches that can be taken to enhance PFC is addressed, as well as recommendations for future research in the area of planning and decision making in the context of care transitions. PMID:26207079

  6. Strategic facility planning improves capital decision making.

    PubMed

    Reeve, J R

    2001-03-01

    A large, Midwestern IDS undertook a strategic facility-planning process to evaluate its facility portfolio and determine how best to allocate future investments in facility development. The IDS assembled a facility-planning team, which initiated the planning process with a market analysis to determine future market demands and identify service areas that warranted facility expansion. The team then analyzed each of the IDS's facilities from the perspective of uniform capacity measurements, highest and best use compared with needs, building condition and investment-worthiness, and facility growth and site development opportunities. Based on results of the analysis, the strategy adopted entailed, in part, shifting some space from inpatient care to ambulatory care services and demolishing and replacing the 11 percent of facilities deemed to be in the worst condition.

  7. Hilots make the family planning scene.

    PubMed

    1974-10-01

    A hilot (birth attendant), Aling Melchora, of Roxas, Oriental Mindora, who does motivation work in family planning is typical of hilots who are found in every barrio throughout the Philippines. She is 58 years old and has been a hilot for more than 30 years. She learned birth attendance in a training course at the Pandacan Puericulture Center in 1940. She averages 3 deliveries a month and 8 IUD acceptances a month. The hilots are a possible strong force in family planning motivation because of their influence and the respect with which people in the community regard them. They are older, experienced, always available, and charge very reasonable rates for services highly trained clinic staff would balk at doing. The Institute of Maternal and Child Health (IMCH) has trained 400 such hilots to do motivation work in family planning. It is noted that in the Philippines, the hilot may yet provide the key to reach the people in the barrios, which is the most important and challenging task for the national program on family planning. PMID:12306912

  8. Hilots make the family planning scene.

    PubMed

    1974-10-01

    A hilot (birth attendant), Aling Melchora, of Roxas, Oriental Mindora, who does motivation work in family planning is typical of hilots who are found in every barrio throughout the Philippines. She is 58 years old and has been a hilot for more than 30 years. She learned birth attendance in a training course at the Pandacan Puericulture Center in 1940. She averages 3 deliveries a month and 8 IUD acceptances a month. The hilots are a possible strong force in family planning motivation because of their influence and the respect with which people in the community regard them. They are older, experienced, always available, and charge very reasonable rates for services highly trained clinic staff would balk at doing. The Institute of Maternal and Child Health (IMCH) has trained 400 such hilots to do motivation work in family planning. It is noted that in the Philippines, the hilot may yet provide the key to reach the people in the barrios, which is the most important and challenging task for the national program on family planning.

  9. Career Planning and Decision-Making for College. AEL Career Decision-Making Program.

    ERIC Educational Resources Information Center

    McKnight, Lola, Ed.

    Six course units and learning activities for the Career Planning and Decision-Making course is presented. The course emphasizes career comprehension, career values, and career action. Career comprehension includes developing knowledge of the world of work and planning and decision-making skills. Career values focus on clarifying, identifying, and…

  10. Making family planning accessible in resource-poor settings.

    PubMed

    Prata, Ndola

    2009-10-27

    It is imperative to make family planning more accessible in low resource settings. The poorest couples have the highest fertility, the lowest contraceptive use and the highest unmet need for contraception. It is also in the low resource settings where maternal and child mortality is the highest. Family planning can contribute to improvements in maternal and child health, especially in low resource settings where overall access to health services is limited. Four critical steps should be taken to increase access to family planning in resource-poor settings: (i) increase knowledge about the safety of family planning methods; (ii) ensure contraception is genuinely affordable to the poorest families; (iii) ensure supply of contraceptives by making family planning a permanent line item in healthcare system's budgets and (iv) take immediate action to remove barriers hindering access to family planning methods. In Africa, there are more women with an unmet need for family planning than women currently using modern methods. Making family planning accessible in low resource settings will help decrease the existing inequities in achieving desired fertility at individual and country level. In addition, it could help slow population growth within a human rights framework. The United Nations Population Division projections for the year 2050 vary between a high of 10.6 and a low of 7.4 billion. Given that most of the growth is expected to come from today's resource-poor settings, easy access to family planning could make a difference of billions in the world in 2050. PMID:19770158

  11. 6 CFR 5.8 - Business information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... requirements of Executive Order 12600 (3 CFR, 1988 Comp., p. 235); or (4) The designation made by the submitter... 6 Domestic Security 1 2010-01-01 2010-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained...

  12. 6 CFR 5.8 - Business information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... requirements of Executive Order 12600 (3 CFR, 1988 Comp., p. 235); or (4) The designation made by the submitter... 6 Domestic Security 1 2013-01-01 2013-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained...

  13. 6 CFR 5.8 - Business information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... requirements of Executive Order 12600 (3 CFR, 1988 Comp., p. 235); or (4) The designation made by the submitter... 6 Domestic Security 1 2011-01-01 2011-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained...

  14. 6 CFR 5.8 - Business information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... requirements of Executive Order 12600 (3 CFR, 1988 Comp., p. 235); or (4) The designation made by the submitter... 6 Domestic Security 1 2014-01-01 2014-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained...

  15. 6 CFR 5.8 - Business information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... requirements of Executive Order 12600 (3 CFR, 1988 Comp., p. 235); or (4) The designation made by the submitter... 6 Domestic Security 1 2012-01-01 2012-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained...

  16. Development of Planning Behaviour and Decision Making Ability of Children

    ERIC Educational Resources Information Center

    Mahapatra, Shamita

    2016-01-01

    Decision making, a complex mental activity underlying the act of choosing from among the alternatives in attaining a goal constitutes the core component of planning, a higher order cognitive process as per the PASS theory of intelligence. An attempt, therefore, has been made in the present study to examine the development of planning behaviour in…

  17. Implementing participatory decision making in forest planning.

    PubMed

    Ananda, Jayanath

    2007-04-01

    Forest policy decisions are often a source of debate, conflict, and tension in many countries. The debate over forest land-use decisions often hinges on disagreements about societal values related to forest resource use. Disagreements on social value positions are fought out repeatedly at local, regional, national, and international levels at an enormous social cost. Forest policy problems have some inherent characteristics that make them more difficult to deal with. On the one hand, forest policy decisions involve uncertainty, long time scales, and complex natural systems and processes. On the other hand, such decisions encompass social, political, and cultural systems that are evolving in response to forces such as globalization. Until recently, forest policy was heavily influenced by the scientific community and various economic models of optimal resource use. However, growing environmental awareness and acceptance of participatory democracy models in policy formulation have forced the public authorities to introduce new participatory mechanisms to manage forest resources. Most often, the efforts to include the public in policy formulation can be described using the lower rungs of Arnstein's public participation typology. This paper presents an approach that incorporates stakeholder preferences into forest land-use policy using the Analytic Hierarchy Process (AHP). An illustrative case of regional forest-policy formulation in Australia is used to demonstrate the approach. It is contended that applying the AHP in the policy process could considerably enhance the transparency of participatory process and public acceptance of policy decisions.

  18. Implementing Participatory Decision Making in Forest Planning

    NASA Astrophysics Data System (ADS)

    Ananda, Jayanath

    2007-04-01

    Forest policy decisions are often a source of debate, conflict, and tension in many countries. The debate over forest land-use decisions often hinges on disagreements about societal values related to forest resource use. Disagreements on social value positions are fought out repeatedly at local, regional, national, and international levels at an enormous social cost. Forest policy problems have some inherent characteristics that make them more difficult to deal with. On the one hand, forest policy decisions involve uncertainty, long time scales, and complex natural systems and processes. On the other hand, such decisions encompass social, political, and cultural systems that are evolving in response to forces such as globalization. Until recently, forest policy was heavily influenced by the scientific community and various economic models of optimal resource use. However, growing environmental awareness and acceptance of participatory democracy models in policy formulation have forced the public authorities to introduce new participatory mechanisms to manage forest resources. Most often, the efforts to include the public in policy formulation can be described using the lower rungs of Arnstein’s public participation typology. This paper presents an approach that incorporates stakeholder preferences into forest land-use policy using the Analytic Hierarchy Process (AHP). An illustrative case of regional forest-policy formulation in Australia is used to demonstrate the approach. It is contended that applying the AHP in the policy process could considerably enhance the transparency of participatory process and public acceptance of policy decisions.

  19. 12 CFR 5.8 - Public notice.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Public notice. 5.8 Section 5.8 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES, POLICIES, AND PROCEDURES FOR... explain in the notice how the transactions are related. (e) Joint public notices accepted. Upon...

  20. Computer-Assisted Community Planning and Decision Making.

    ERIC Educational Resources Information Center

    College of the Atlantic, Bar Harbor, ME.

    The College of the Atlantic (COA) developed a broad-based, interdisciplinary curriculum in ecological policy and community planning and decision-making that incorporates two primary computer-based tools: ARC/INFO Geographic Information System (GIS) and STELLA, a systems-dynamics modeling tool. Students learn how to use and apply these tools…

  1. 12 CFR 5.8 - Public notice.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CORPORATE ACTIVITIES Rules of General Applicability § 5.8 Public notice. (a) General. An applicant shall... transaction, or a series of transactions, to be a single filing for purposes of the publication...

  2. 12 CFR 5.8 - Public notice.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CORPORATE ACTIVITIES Rules of General Applicability § 5.8 Public notice. (a) General. An applicant shall... transaction, or a series of transactions, to be a single filing for purposes of the publication...

  3. 12 CFR 5.8 - Public notice.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CORPORATE ACTIVITIES Rules of General Applicability § 5.8 Public notice. (a) General. An applicant shall... transaction, or a series of transactions, to be a single filing for purposes of the publication...

  4. Homecare Nurses' Decision-Making During Admission Care Planning.

    PubMed

    Sockolow, Paulina; Bass, Ellen J; Eberle, Carl L; Bowles, Kathryn H

    2016-01-01

    The re-hospitalization rate of homecare patients within 60 days of hospital discharge is 30%. Enhanced care planning based on better information may reduce this rate. However, very little is known about the homecare admission and care planning processes. The research team collected data during observations of three nursing visits to admit homecare patients in Camden NJ, and conducted thematic content analysis on these data. Human factors methods helped to identify nurse decision-making related to selection of the plan of care problems, non-nursing resources, and the nursing visit pattern. They identified how the electronic health record (EHR) assisted the nurse in visit pattern frequency decisions. Major themes that emerged included reduced efficiency due to use of redundant intra-team communication methods to augment EHR documentation, redundant documentation, and workarounds and reorganization of clinical workflow.

  5. Homecare Nurses' Decision-Making During Admission Care Planning.

    PubMed

    Sockolow, Paulina; Bass, Ellen J; Eberle, Carl L; Bowles, Kathryn H

    2016-01-01

    The re-hospitalization rate of homecare patients within 60 days of hospital discharge is 30%. Enhanced care planning based on better information may reduce this rate. However, very little is known about the homecare admission and care planning processes. The research team collected data during observations of three nursing visits to admit homecare patients in Camden NJ, and conducted thematic content analysis on these data. Human factors methods helped to identify nurse decision-making related to selection of the plan of care problems, non-nursing resources, and the nursing visit pattern. They identified how the electronic health record (EHR) assisted the nurse in visit pattern frequency decisions. Major themes that emerged included reduced efficiency due to use of redundant intra-team communication methods to augment EHR documentation, redundant documentation, and workarounds and reorganization of clinical workflow. PMID:27332156

  6. Linking Assessment to Decision Making in Water Resources Planning - Decision Making Frameworks and Case Study Evaluations

    NASA Astrophysics Data System (ADS)

    Broman, D.; Gangopadhyay, S.; Simes, J.

    2015-12-01

    Climate assessments have become an accepted and commonly used component of long term water management and planning. There is substantial variation in the methods used in these assessments; however, managers and decision-makers have come to value their utility to identify future system limitations, and to evaluate future alternatives to ensure satisfactory system performance. A new set of decision-making frameworks have been proposed, including robust decision making (RDM), and decision scaling, that directly address the deep uncertainties found in both future climate, and non-climatic factors. Promising results have been obtained using these new frameworks, offering a more comprehensive understanding of future conditions leading to failures, and identification of measures to address these failures. Data and resource constraints have limited the use of these frameworks within the Bureau of Reclamation. We present here a modified framework that captures the strengths of previously proposed methods while using a suite of analysis tool that allow for a 'rapid climate assessment' to be performed. A scalable approach has been taken where more complex tools can be used if project resources allow. This 'rapid assessment' is demonstrated through two case studies on the Santa Ana and Colorado Rivers where previous climate assessments have been completed. Planning-level measures are used to compare how decision making is affected when using this new decision making framework.

  7. Risky Group Decision-Making Method for Distribution Grid Planning

    NASA Astrophysics Data System (ADS)

    Li, Cunbin; Yuan, Jiahang; Qi, Zhiqiang

    2015-12-01

    With rapid speed on electricity using and increasing in renewable energy, more and more research pay attention on distribution grid planning. For the drawbacks of existing research, this paper proposes a new risky group decision-making method for distribution grid planning. Firstly, a mixing index system with qualitative and quantitative indices is built. On the basis of considering the fuzziness of language evaluation, choose cloud model to realize "quantitative to qualitative" transformation and construct interval numbers decision matrices according to the "3En" principle. An m-dimensional interval numbers decision vector is regarded as super cuboids in m-dimensional attributes space, using two-level orthogonal experiment to arrange points uniformly and dispersedly. The numbers of points are assured by testing numbers of two-level orthogonal arrays and these points compose of distribution points set to stand for decision-making project. In order to eliminate the influence of correlation among indices, Mahalanobis distance is used to calculate the distance from each solutions to others which means that dynamic solutions are viewed as the reference. Secondly, due to the decision-maker's attitude can affect the results, this paper defines the prospect value function based on SNR which is from Mahalanobis-Taguchi system and attains the comprehensive prospect value of each program as well as the order. At last, the validity and reliability of this method is illustrated by examples which prove the method is more valuable and superiority than the other.

  8. Transport policy-making and planning Javanese cities

    SciTech Connect

    Dimitriou, H.

    1995-12-31

    Based on findings of field studies in five Javanese cities in Indonesia, this paper looks at a hierarchy of settlements and investigates what aspects of urban development and the transport sector most influences transport policy-making and planning in the country. The paper highlights the presence of a community hierarchy within these settlements with consonant trip-making patterns and the widespread mis-use of certain transport modes. The paper cross-relates observed transport problems and policy issues diagnosed from the five Javanese cities with an earlier prepared national agenda of urban transport policy issues and problems. This is done with a view to arriving at more sensitive policy and planning responses nationwide for cities of different kinds in Indonesia. The paper commences with an explanation of the settlement hierarchy and community structure employed by Indonesian government planners. An attempt is then made to relate this hierarchy and structure to the five cities studied. Within this context, factors affecting urban transport are discussed and tabulated against the above cities settlement hierarchy. These include aspects of: settlement size, structure and area; settlement development policy, urban for, density and topography; and travel and transport characteristics. An attempt is made to match this settlement hierarchy (and its constituent community structure) with a conceptualized hierarchy of transport modes, simultaneously investigating: the relationship between urban communities and assigned road hierarchies; community-based travel demand and trip-making characteristics; and the relationship between travel, speed and distance. From this an assessment is made of the performance and current use and mis-use of such transport modes.

  9. A Methodology to Support Decision Making in Flood Plan Mitigation

    NASA Astrophysics Data System (ADS)

    Biscarini, C.; di Francesco, S.; Manciola, P.

    2009-04-01

    The focus of the present document is on specific decision-making aspects of flood risk analysis. A flood is the result of runoff from rainfall in quantities too great to be confined in the low-water channels of streams. Little can be done to prevent a major flood, but we may be able to minimize damage within the flood plain of the river. This broad definition encompasses many possible mitigation measures. Floodplain management considers the integrated view of all engineering, nonstructural, and administrative measures for managing (minimizing) losses due to flooding on a comprehensive scale. The structural measures are the flood-control facilities designed according to flood characteristics and they include reservoirs, diversions, levees or dikes, and channel modifications. Flood-control measures that modify the damage susceptibility of floodplains are usually referred to as nonstructural measures and may require minor engineering works. On the other hand, those measures designed to modify the damage potential of permanent facilities are called non-structural and allow reducing potential damage during a flood event. Technical information is required to support the tasks of problem definition, plan formulation, and plan evaluation. The specific information needed and the related level of detail are dependent on the nature of the problem, the potential solutions, and the sensitivity of the findings to the basic information. Actions performed to set up and lay out the study are preliminary to the detailed analysis. They include: defining the study scope and detail, the field data collection, a review of previous studies and reports, and the assembly of needed maps and surveys. Risk analysis can be viewed as having many components: risk assessment, risk communication and risk management. Risk assessment comprises an analysis of the technical aspects of the problem, risk communication deals with conveying the information and risk management involves the decision process

  10. Multi-site production planning in hybrid make-to-stock/make-to-order production environment

    NASA Astrophysics Data System (ADS)

    Rafiei, Hamed; Rabbani, Masoud; Kokabi, Reza

    2014-06-01

    Today competitive environment has enforced practitioners and researchers to pay great attention to issues enhancing both production and marketing competitiveness. To do so, it has been obligatory for the firms to consider production side activities while customer requirements are on the other side of competition. In this regard, hybrid make-to-stock (MTS)/make-to-order (MTO) production systems have revealed outstanding results. This paper addresses multi-site production planning of a hybrid manufacturing firm for the first time in the hybrid systems' body of literature. In this regard, a network of suppliers, manufacturers and customers is considered for which a mixed-integer mathematical model is proposed. Objective function of the proposed mathematical model seeks to maximize profitability of the manufacturing firm. Because of computational complexity of the developed mathematical model, a genetic algorithm is developed upon which numerical experiments are reported in order to show validity and applicability of the proposed model.

  11. 7 CFR 1924.10 - Making changes in the planned development.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Making changes in the planned development. 1924.10... Development § 1924.10 Making changes in the planned development. The borrower may request changes in the planned development in accordance with this section. (a) Authority of the County Supervisor. The...

  12. Optimizing perioperative decision making: improved information for clinical workflow planning.

    PubMed

    Doebbeling, Bradley N; Burton, Matthew M; Wiebke, Eric A; Miller, Spencer; Baxter, Laurence; Miller, Donald; Alvarez, Jorge; Pekny, Joseph

    2012-01-01

    Perioperative care is complex and involves multiple interconnected subsystems. Delayed starts, prolonged cases and overtime are common. Surgical procedures account for 40-70% of hospital revenues and 30-40% of total costs. Most planning and scheduling in healthcare is done without modern planning tools, which have potential for improving access by assisting in operations planning support. We identified key planning scenarios of interest to perioperative leaders, in order to examine the feasibility of applying combinatorial optimization software solving some of those planning issues in the operative setting. Perioperative leaders desire a broad range of tools for planning and assessing alternate solutions. Our modeled solutions generated feasible solutions that varied as expected, based on resource and policy assumptions and found better utilization of scarce resources. Combinatorial optimization modeling can effectively evaluate alternatives to support key decisions for planning clinical workflow and improving care efficiency and satisfaction.

  13. 5.8 X-ray Calorimeters

    NASA Technical Reports Server (NTRS)

    Porter, F. Scott

    2008-01-01

    X-ray calorimeter instruments for astrophysics have seen rapid development since they were invented in 1984. The prime instrument on all currently planned X-ray spectroscopic observatories is based on calorimeter technology. This relatively simple detection concept that senses the energy of an incident photon by measuring the temperature rise of an absorber material at very low temperatures, can form the basis of a very high performance, non-dispersive spectrometer. State-of-the-art calorimeter instruments have resolving powers of over 3000, large simultaneous band-passes, and near unit efficiency. This coupled with the intrinsic imaging capability of a pixilated x-ray calorimeter array, allows true spectral-spatial instruments to be constructed. In this chapter I briefly review the detection scheme, the state-of-the-art in X-ray calorimeter instruments and the future outlook for this technology.

  14. Planning for Success: Integrating Analysis with Decision Making.

    ERIC Educational Resources Information Center

    Goho, James; Webb, Ken

    2003-01-01

    Describes a successful strategic planning process at a large community college, which linked the analytic inputs of research with the authority and intuition of leaders. Reports key factors attributed to the process' success, including a collegial and organized structure, detailed project management plans, and confidence in the environmental scan.…

  15. Management and Decision-Making in Educational Planning.

    ERIC Educational Resources Information Center

    Kravetz, Nathan, Ed.

    This IIEP seminar focused on administrative, management, supervisory, and decisionmaking techniques that are useful in the educational planning process. The techniques studied included: delphi, program evaluation and review technique (PERT), and program planning and budgeting systems (PPBS). Various experts presented papers on these techniques,…

  16. Making twin concerns of family planning and primary health care.

    PubMed

    Wang, Y

    1985-10-01

    The implementation of the Integrated FP/MCH/Parasite Control project by JOICFP in 1984 was envisioned to strengthen international cooperation, promote international exchange of knowledge and expand approaches in the practice of family planning. 2 municipalities in China were selected as pilot project areas. The objectives set in the 3-year plan of the integrated project are: to publicize the advantages of family planning and improve people's knowledge and practice of family planning; to stengthen technical guidance on family planning and control the growth and improve the quality of the population; to improve maternal and child care; and to reduce the infection rate of soil-transmitted helminthiasis. Steering committees on the integrated project at the municipal, county, township and village levels were set up in the pilot areas; the significance of the project has been communicated through film and slide presentations. Training courses for the administrative workers and technicians have been held. As a result of the family planning education activities, the contraceptive rates in the 2 pilot areas remained stable at 85%. Neonatal mortality was reduced significantly. Parasite control has benefitted 52,546 people in the pilot areas. An improvement was noted in environmental hygiene, the proper disposal of waste and the provision of safe drinking water. Further improvement can be achieved by intensifying public health education in the project areas, improving working systems and accomplishing all the tasks that the integrated project has set forth.

  17. 7 CFR 1924.10 - Making changes in the planned development.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Making changes in the planned development. 1924.10 Section 1924.10 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE... Development § 1924.10 Making changes in the planned development. The borrower may request changes in...

  18. 7 CFR 1924.10 - Making changes in the planned development.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Making changes in the planned development. 1924.10 Section 1924.10 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE... Development § 1924.10 Making changes in the planned development. The borrower may request changes in...

  19. 7 CFR 1924.10 - Making changes in the planned development.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Making changes in the planned development. 1924.10 Section 1924.10 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE... Development § 1924.10 Making changes in the planned development. The borrower may request changes in...

  20. 1 CFR 5.8 - Form of citation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Form of citation. 5.8 Section 5.8 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.8 Form of citation. Without prejudice to any other form of citation, Federal Register material may be cited by...

  1. 1 CFR 5.8 - Form of citation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Form of citation. 5.8 Section 5.8 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.8 Form of citation. Without prejudice to any other form of citation, Federal Register material may be cited by...

  2. 1 CFR 5.8 - Form of citation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Form of citation. 5.8 Section 5.8 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.8 Form of citation. Without prejudice to any other form of citation, Federal Register material may be cited by...

  3. 1 CFR 5.8 - Form of citation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Form of citation. 5.8 Section 5.8 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.8 Form of citation. Without prejudice to any other form of citation, Federal Register material may be cited by...

  4. 1 CFR 5.8 - Form of citation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Form of citation. 5.8 Section 5.8 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.8 Form of citation. Without prejudice to any other form of citation, Federal Register material may be cited by...

  5. 14 CFR 1216.303 - NEPA process in NASA planning and decision making.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false NEPA process in NASA planning and decision...) § 1216.303 NEPA process in NASA planning and decision making. (a) NEPA requires the systematic... the NEPA process with NASA project and program planning improves Agency decisions and ensures that:...

  6. 14 CFR § 1216.303 - NEPA process in NASA planning and decision making.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false NEPA process in NASA planning and decision... Act (NEPA) § 1216.303 NEPA process in NASA planning and decision making. (a) NEPA requires the... integration of the NEPA process with NASA project and program planning improves Agency decisions and...

  7. Improvements to Strategic Planning and Implementation through Enhanced Correlation with Decision-Making Frameworks

    ERIC Educational Resources Information Center

    McCready, John W.

    2010-01-01

    The purpose of this study was to examine use of decision-making tools and feedback in strategic planning in order to develop a rigorous process that would promote the efficiency of strategic planning for acquisitions in the United States Coast Guard (USCG). Strategic planning is critical to agencies such as the USCG in order to be effective…

  8. Community Engagement and Strategic Planning: Making the Commitment Real

    ERIC Educational Resources Information Center

    Zimpher, Nancy L.

    2006-01-01

    Embedding community engagement into the fabric of the university requires a well articulated strategic vision. This article shares lessons learned by the president of a comprehensive research university, focusing primarily on two case studies, both urban institutions. The article discusses two strategic planning processes-one at the University of…

  9. South Korea: Language Policy and Planning in the Making

    ERIC Educational Resources Information Center

    Song, Jae Jung

    2012-01-01

    This monograph discusses South Korea's language situation in a language policy and planning context. This monograph consists of four parts. Part 1 presents a genetic, typological and sociolinguistic description of South Korea's national language, and an overview of minority languages, including English as well as other languages, recently…

  10. Make safety programs work efficiently with an effective management plan

    SciTech Connect

    Lyle, D.

    1995-07-01

    Like budgets or any other major projects, safety works better when everyone in the company commits to manage the program effectively. Let someone overspend a budget or miss a projected revenue plan and a company moves quickly to correct the problem. However, there is a tendency to ignore a manager whose department has a poor safety record, as though it`s bad luck.

  11. A Planning and Decision-Making Framework for Ecological Restoration.

    ERIC Educational Resources Information Center

    Wyant, James G.; And Others

    1995-01-01

    Provides a definition for restoration ecology that is suitable for extensive terrestrial applications and presents a decision framework to help organize different phases of the decision process. Encourages a wider spectrum of participants and decisions than have been traditionally employed for restoration planning. (AIM)

  12. Plan now to make your retirement active, productive.

    PubMed

    Schlepp, S

    1989-12-01

    In his book Planning to the Years Ahead, Lester I. Tenney, PhD, professor emeritus at Arizona State University, Tempe, links Abraham Maslow's hierarchy of needs to retirement planning. According to Maslow, economic and security needs can be achieved through a family environment (eg, food clothing, shelter), and social acceptance, self-worth, and self-satisfaction can be achieved from social interaction, work, or leisure activities. After the basic needs of food, clothing, and shelter have been achieved, people are able to move to the next level of achieving safety and security. The level of dependency that people have on satisfying these needs through work will determine how well they are at adapting to retirement. The more people depend on work alone, the harder will be the adjustment; people who are less dependent on work will find retirement easier to accept.

  13. Planning for Desperate Climate Intervention: can it Make Sense?

    NASA Astrophysics Data System (ADS)

    Duncan, Robert

    2014-07-01

    The three National Academies of the United States, working together, authored a comprehensive report in 1992 titled: Policy Implications of Greenhouse Warming: Mitigation, Adaptation, and the Science Base. The authors discussed various possible methods of geoengineering to mitigate the adverse climate effects of the slow, steady buildup of greenhouse gasses in the Earth's atmosphere. Subsequently far less expensive, clever designs were developed by inventors such as Bill Gates and his collaborators, and these have been patented. Many of the techniques in this geoengineering proposition were commonly considered as methods of selectively polluting the upper atmosphere to block the solar luminosity, and hence they met with staunch resistance from the international scientific community. At the time, these geoengineering approaches were proposed as a method of countering the slow steady increase of the earth's temperature that was assumed to be a consequence of the increase in concentration of atmospheric molecules that contain carbon, such as CO2 and CH4. Such intentional intervention in a system as complex as the earth's atmosphere was considered by most scientists, including the authors, as reckless. Within this paper, we propose that the less expensive of these geoengineering plans be reconsidered, but that such a system never be deployed or tested at scale unless a genuine climate runaway condition arises in the future. The more economically compelling approaches should be further tested at the `lab bench' level, and in small laboratory-scale tests, and simulations. A comprehensive plan should be developed to manufacture the required materials at scale and to finalize the design of the necessary system, but no such deployment should be entered into at this time. The many risks of an intense, sudden release of greenhouse gasses, mainly methane and carbon dioxide from geologic sources, are reviewed briefly herein. We consider it only prudent to develop an economical

  14. Decision making, movement planning and statistical decision theory.

    PubMed

    Trommershäuser, Julia; Maloney, Laurence T; Landy, Michael S

    2008-08-01

    We discuss behavioral studies directed at understanding how probability information is represented in motor and economic tasks. By formulating the behavioral tasks in the language of statistical decision theory, we can compare performance in equivalent tasks in different domains. Subjects in traditional economic decision-making tasks often misrepresent the probability of rare events and typically fail to maximize expected gain. By contrast, subjects in mathematically equivalent movement tasks often choose movement strategies that come close to maximizing expected gain. We discuss the implications of these different outcomes, noting the evident differences between the source of uncertainty and how information about uncertainty is acquired in motor and economic tasks.

  15. "Leaving before she leaves": considering future family when making career plans.

    PubMed

    Ganginis Del Pino, Heather V; O'Brien, Karen M; Mereish, Ethan; Miller, Matthew J

    2013-07-01

    An instrument was developed to measure the extent to which people consider future children and romantic partners when planning for a career (i.e., the PLAN scale). Two independent factor-analytic studies of a total of 726 college women were conducted to assess the factor structure and psychometric properties of this measure. Results suggested that the PLAN represents a general Considering Future Family When Making Career Plans factor and 2 domain-specific factors: Considering Children and Prioritizing and Compromising for Partner. Suggestions for future research and practice using the PLAN scale are provided.

  16. Making Thinking Visible: Collaborative Planning--Concepts, Processes, and Assignments: A Casebook.

    ERIC Educational Resources Information Center

    Aston, Jean A., Ed.; And Others

    This casebook is part of a set of materials written by the members of the Making Thinking Visible Project. It offers high school, college, and community college teachers' multiple perspectives on the teaching and learning of collaborative planning, and on classroom inquiry and practice. The casebook explains collaborative planning (a writing…

  17. American Indian farm planning: an analytical approach to tribal decision making

    SciTech Connect

    Norton, G.W.; Easter, K.W.; Roe, T.L.

    1980-11-01

    A multiyear linear programming model is used to assist an American Indian tribe develop agricultural plans for its tribal farm. Five-year crop, livestock, and investment plans are generated consistent with the tribal resource base, goals, and decision-making structure. The model has influenced the tribal farm decision-making process and provided the primary farming guide for 1979 and 1980. Frequent communication with the tribe was crucial in developing the model. Adequate updating procedures will be important in future farm planning. 13 references.

  18. Intelligent Aircraft Damage Assessment, Trajectory Planning, and Decision-Making under Uncertainty

    NASA Astrophysics Data System (ADS)

    Lopez, Israel; Sarigul-Klijn, Nesrin

    Situational awareness and learning are necessary to identify and select the optimal set of mutually non-exclusive hypothesis in order to maximize mission performance and adapt system behavior accordingly. This paper presents a hierarchical and decentralized approach for integrated damage assessment and trajectory planning in aircraft with uncertain navigational decision-making. Aircraft navigation can be safely accomplished by properly addressing the following: decision-making, obstacle perception, aircraft state estimation, and aircraft control. When in-flight failures or damage occur, rapid and precise decision-making under imprecise information is required in order to regain and maintain control of the aircraft. To achieve planned aircraft trajectory and complete safe landing, the uncertainties in system dynamics of the damaged aircraft need to be learned and incorporated at the level of motion planning. The damaged aircraft is simulated via a simplified kinematic model. The different sources and perspectives of uncertainties in the damage assessment process and post-failure trajectory planning are presented and classified. The decision-making process for an emergency motion planning and landing is developed via the Dempster-Shafer evidence theory. The objective of the trajectory planning is to arrive at a target position while maximizing the safety of the aircraft given uncertain conditions. Simulations are presented for an emergency motion planning and landing that takes into account aircraft dynamics, path complexity, distance to landing site, runway characteristics, and subjective human decision.

  19. Choice Set Size and Decision-Making: The Case of Medicare Part D Prescription Drug Plans

    PubMed Central

    Bundorf, M. Kate; Szrek, Helena

    2013-01-01

    Background The impact of choice on consumer decision-making is controversial in U.S. health policy. Objective Our objective was to determine how choice set size influences decision-making among Medicare beneficiaries choosing prescription drug plans. Methods We randomly assigned members of an internet-enabled panel age 65 and over to sets of prescription drug plans of varying sizes (2, 5, 10, and 16) and asked them to choose a plan. Respondents answered questions about the plan they chose, the choice set, and the decision process. We used ordered probit models to estimate the effect of choice set size on the study outcomes. Results Both the benefits of choice, measured by whether the chosen plan is close to the ideal plan, and the costs, measured by whether the respondent found decision-making difficult, increased with choice set size. Choice set size was not associated with the probability of enrolling in any plan. Conclusions Medicare beneficiaries face a tension between not wanting to choose from too many options and feeling happier with an outcome when they have more alternatives. Interventions that reduce cognitive costs when choice sets are large may make this program more attractive to beneficiaries. PMID:20228281

  20. Eukaryotic ribosomes that lack a 5.8S RNA

    NASA Technical Reports Server (NTRS)

    Vossbrinck, C. R.; Woese, C. R.

    1986-01-01

    The 5.8S ribosomal RNA is believed to be a universal eukaryotic characteristic. It has no (size) counterpart among the prokaryotes, although its sequence is homologous with the first 150 or so nucleotides of the prokaryotic large subunit (23S) ribosomal RNA. An exception to this rule is reported here. The microsporidian Vairimorpha necatrix is a eukaryote that has no 5.8S rRNA. As in the prokaryotes, it has a single large subunit rRNA, whose 5-prime region corresponds to the 5.8S rRNA.

  1. Decision-making and evacuation planning for flood risk management in the Netherlands.

    PubMed

    Kolen, Bas; Helsloot, Ira

    2014-07-01

    A traditional view of decision-making for evacuation planning is that, given an uncertain threat, there is a deterministic way of defining the best decision. In other words, there is a linear relation between threat, decision, and execution consequences. Alternatives and the impact of uncertainties are not taken into account. This study considers the 'top strategic decision-making' for mass evacuation owing to flooding in the Netherlands. It reveals that the top strategic decision-making process itself is probabilistic because of the decision-makers involved and their crisis managers (as advisers). The paper concludes that deterministic planning is not sufficient, and it recommends probabilistic planning that considers uncertainties in the decision-making process itself as well as other uncertainties, such as forecasts, citizens responses, and the capacity of infrastructure. This results in less optimistic, but more realistic, strategies and a need to pay attention to alternative strategies.

  2. Climate Change Scenario Planning in Alaska's National Parks: Stakeholder Involvement in the Decision-Making Process

    SciTech Connect

    Ernst, Kathleen M; Van Riemsdijk, Dr. Micheline

    2013-01-01

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decision-making process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  3. Making parks make a difference: poor alignment of policy, planning and management with protected-area impact, and ways forward

    PubMed Central

    Pressey, Robert L.; Visconti, Piero; Ferraro, Paul J.

    2015-01-01

    Policy and practice around protected areas are poorly aligned with the basic purpose of protection, which is to make a difference. The difference made by protected areas is their impact, defined in program evaluation as the outcomes arising from protection relative to the counterfactual of no protection or a different form of protection. Although impact evaluation of programs is well established in fields such as medicine, education and development aid, it is rare in nature conservation. We show that the present weak alignment with impact of policy targets and operational objectives for protected areas involves a great risk: targets and objectives can be achieved while making little difference to the conservation of biodiversity. We also review potential ways of increasing the difference made by protected areas, finding a poor evidence base for the use of planning and management ‘levers’ to better achieve impact. We propose a dual strategy for making protected areas more effective in their basic role of saving nature, outlining ways of developing targets and objectives focused on impact while also improving the evidence for effective planning and management. PMID:26460132

  4. Making parks make a difference: poor alignment of policy, planning and management with protected-area impact, and ways forward.

    PubMed

    Pressey, Robert L; Visconti, Piero; Ferraro, Paul J

    2015-11-01

    Policy and practice around protected areas are poorly aligned with the basic purpose of protection, which is to make a difference. The difference made by protected areas is their impact, defined in program evaluation as the outcomes arising from protection relative to the counterfactual of no protection or a different form of protection. Although impact evaluation of programs is well established in fields such as medicine, education and development aid, it is rare in nature conservation. We show that the present weak alignment with impact of policy targets and operational objectives for protected areas involves a great risk: targets and objectives can be achieved while making little difference to the conservation of biodiversity. We also review potential ways of increasing the difference made by protected areas, finding a poor evidence base for the use of planning and management 'levers' to better achieve impact. We propose a dual strategy for making protected areas more effective in their basic role of saving nature, outlining ways of developing targets and objectives focused on impact while also improving the evidence for effective planning and management.

  5. Climate change scenario planning in Alaska's National Parks: Stakeholder involvement in the decision-making process

    SciTech Connect

    Ernst, Kathleen M; Van Riemsdijk, Dr. Micheline

    2013-01-01

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decisionmaking process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  6. Radial collapse and physical mechanism of carbon nanotube with divacancy and 5-8-5 defects

    NASA Astrophysics Data System (ADS)

    Zhang, Ya-Ping; Ling, Cui-Cui; Li, Gui-Xia; Zhu, Hai-Feng; Zhang, Meng-Yu

    2015-04-01

    By employing molecular mechanics and molecular dynamics simulations, we investigate the radial collapses and elasticities of different chiral single-walled carbon nanotubes (SWCNTs) with divacancy, and 5-8-5 defects. It is found that divacancy and 5-8-5 defect can reduce the collapse pressure (Pc) of SWCNT (10, 10) while 5-8-5 defect can greatly increase Pc of SWCNT (17, 0). For example, 5-8-5 defect can make Pc of SWCNT (17, 0) increase by 500%. A model is established to understand the effects of chirality, divacancy, and 5-8-5 defect on radial collapse of SWCNTs. The results are particularly of value for understanding the mechanical behavior of SWCNT with divacancy, and the 5-8-5 defect that may be considered as a filler of high loading composites. Project supported by the National Natural Science Foundation of China (Grant No. 11374372), Natural Science Foundation of Shandong Province, China (Grant No. ZR2014EMQ006), the Postdoctoral Science Foundation of China (Grant No. 2014M551983), the Postdoctoral Applied Research Foundation of Qingdao City, China (Grant No. 2014), the Fundamental Research Funds for the Central Universities, China (Grant Nos. 12CX04087A and 14CX02018A), and the Qingdao Science and Technology Program, China (Grant No. 14-2-4-27-jch).

  7. Making the End as Good as the Beginning: Financial Planning and Retirement for Women Plastic Surgeons.

    PubMed

    Johnson, Debra J; Shenaq, Deana; Thakor, Manisha

    2016-10-01

    Financial planning is critically important to ensure financial security both during a plastic surgical career and in retirement. Unfortunately, plastic surgery training includes very little in the way of financial planning. The information that is available in the literature is mostly geared toward men. Women, with longer lifespans and more family care responsibilities, have unique needs when it comes to financial planning. Adequate attention must also be paid to life after retirement. A plastic surgical career can be all-encompassing, and thus women need to carefully plan volunteer activities, new hobbies, and even a second career to make their retirement years fulfilling and enjoyable. Key points regarding financial planning during the various phases of a woman plastic surgeon's career are discussed. Options for retirement are presented. PMID:27673523

  8. Making the End as Good as the Beginning: Financial Planning and Retirement for Women Plastic Surgeons.

    PubMed

    Johnson, Debra J; Shenaq, Deana; Thakor, Manisha

    2016-10-01

    Financial planning is critically important to ensure financial security both during a plastic surgical career and in retirement. Unfortunately, plastic surgery training includes very little in the way of financial planning. The information that is available in the literature is mostly geared toward men. Women, with longer lifespans and more family care responsibilities, have unique needs when it comes to financial planning. Adequate attention must also be paid to life after retirement. A plastic surgical career can be all-encompassing, and thus women need to carefully plan volunteer activities, new hobbies, and even a second career to make their retirement years fulfilling and enjoyable. Key points regarding financial planning during the various phases of a woman plastic surgeon's career are discussed. Options for retirement are presented.

  9. A Relational Approach to Moral Decision-Making: The Majority Opinion in "Planned Parenthood v. Casey."

    ERIC Educational Resources Information Center

    Sullivan, Patricia A.; Goldzwig, Steven R.

    1995-01-01

    Defines a relational approach to moral reasoning. Notes that the Supreme Court, in "Planned Parenthood v. Casey," rejected simplistic approaches to moral reasoning and acknowledged the complex web of relationships involved in abortion decision making. Suggests that rhetoricians "revision" the art of persuasion to place more emphasis on relational…

  10. The Effects of Scenario Planning on Participant Decision-Making Style

    ERIC Educational Resources Information Center

    Chermack, Thomas J.; Nimon, Kim

    2008-01-01

    This research examines changes in decision-making styles as a result of participation in scenario planning. A quasi-experimental pretest-posttest design and several nonparametric tests were used to analyze data gathered from research participants in a technology firm in the Northeastern United States. Results show that participants tend to…

  11. Career Development Strivings: Assessing Goals and Motivation in Career Decision-Making and Planning

    ERIC Educational Resources Information Center

    Dik, Bryan J.; Sargent, Adam M.; Steger, Michael F.

    2008-01-01

    This article describes and demonstrates a novel approach to assessing goals and motives among individuals engaged in the career decision-making and planning process. Participants generated five career development strivings, rated each striving along several dimensions (self-efficacy, outcome expectations, sense of calling, spiritual significance,…

  12. 77 FR 20648 - Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental Dental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... COMMISSION Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental Dental Positioning Adjustment Appliances, the Appliances Made Therefrom, and Methods of Making the Same; Institution... of certain digital models, digital data, and treatment plans for use in making incremental...

  13. Global Issues in the Intermediate Classroom, Grades 5-8.

    ERIC Educational Resources Information Center

    Johnson, Jacquelyn; Benegar, John

    This publication contains teacher developed activities for teaching about global issues in grades 5-8. The self-contained activities are organized into three major parts. Part I, "Global Awareness," introduces students to the concept of global education. Students are made aware of the nature of the world and the part they play in it as inhabitants…

  14. 17 CFR 5.8 - Aggregate retail forex assets.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Aggregate retail forex assets... FOREIGN CURRENCY TRANSACTIONS § 5.8 Aggregate retail forex assets. (a) Each retail foreign exchange dealer and futures commission merchant offering or engaging in retail forex transactions shall calculate...

  15. Ideas: NCTM Standards-Based Instruction, Grades 5-8.

    ERIC Educational Resources Information Center

    Hynes, Michael C., Ed.

    This document is a collection of activity-based mathematics lessons for grades 5-8 from the "Ideas" department in "Arithmetic Teacher: Mathematics Education through the Middle Grades." Each lesson includes background information, objectives, directions, extensions, and student worksheets. A matrix is included which correlates the titles of the…

  16. 76 FR 58807 - An Assessment of Decision-Making Processes: Evaluation of Where Land Protection Planning Can...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... Incorporate Climate Change Information-- Release of Final Report AGENCY: Environmental Protection Agency (EPA... Decision-Making Processes: Evaluation of Where Land Protection Planning can Incorporate Climate Change... planning can incorporate climate change impacts information into programs. The assessment revealed...

  17. Robust Decision Making and Info-Gap Decision Theory for water resource system planning

    NASA Astrophysics Data System (ADS)

    Matrosov, Evgenii S.; Woods, Ashley M.; Harou, Julien J.

    2013-06-01

    Stationarity assumptions of linked human-water systems are frequently invalid given the difficult-to-predict changes affecting such systems. In this case water planning occurs under conditions of deep or severe uncertainty, where the statistical distributions of future conditions and events are poorly known. In such situations predictive system simulation models are typically run under different scenarios to evaluate the performance of future plans under different conditions. Given that there are many possible plans and many possible futures, which simulations will lead to the best designs? Robust Decision Making (RDM) and Info-Gap Decision Theory (IGDT) provide a structured approach to planning complex systems under such uncertainty. Both RDM and IGDT make repeated use of trusted simulation models to evaluate different plans under different future conditions. Both methods seek to identify robust rather than optimal decisions, where a robust decision works satisfactorily over a broad range of possible futures. IGDT efficiently charts system performance with robustness and opportuneness plots summarising system performance for different plans under the most dire and favourable sets of future conditions. RDM samples a wider range of dire, benign and opportune futures and offers a holistic assessment of the performance of different options. RDM also identifies through ‘scenario discovery' which combinations of uncertain future stresses lead to system vulnerabilities. In our study we apply both frameworks to a water resource system planning problem: London's water supply system expansion in the Thames basin, UK. The methods help identify which out of 20 proposed water supply infrastructure portfolios is the most robust given severely uncertain future hydrological inflows, water demands and energy prices. Multiple criteria of system performance are considered: service reliability, storage susceptibility, capital and operating cost, energy use and environmental flows

  18. Male involvement in family planning decision making in sub-Saharan Africa- what the evidence suggests.

    PubMed

    Vouking, Marius Zambou; Evina, Christine Danielle; Tadenfok, Carine Nouboudem

    2014-01-01

    The World Health Organization (WHO) estimated in 2012 that 287,000 maternal deaths occurred in 2010; sub-Saharan Africa (56%) and Southern Asia (29%) accounted for the global burden of maternal deaths. Men are also recognized to be responsible for the large proportion of ill reproductive health suffered by their female partners. Male involvement helps not only in accepting a contraceptive but also in its effective use and continuation. The objectives were to assess men's knowledge, attitude, and practice of modern contraceptive methods; determine the level of spousal communication about family planning decision making; and investigate the correlates of men's opinion about their roles in family planning decision making. We searched the following electronic databases from January 1995 to December 2013: Medline, Embase, CINAHL, LILAS, International Bibliography of Social Sciences, Social Services Abstracts, and Sociological Abstracts. Along with MeSH terms and relevant keywords, we used the Cochrane Highly Sensitive Search Strategy for identifying reports of articles in PubMed. There were no restrictions to language or publication status. Of 137 hits, 7 papers met the inclusion criteria. The concept of family planning was well known to men. In the Nigerian study, almost (99%) men were aware of the existence of modern contraceptives, and most of them were aware of at least two modern methods. Awareness of the condom was highest (98%). In the Malawi study, all of the participants reported that they were not using contraception before the intervention. In Ethiopia, above 90% of male respondents have supported and approved using and choosing family planning methods, but none of them practiced terminal methods. Generally, more male respondents disagreed than agreed that men should make decisions about selected family planning issues in the family. Decision-making dynamics around method choice followed a slightly different pattern. According to female participants

  19. Breast cancer therapy planning - a novel support concept for a sequential decision making problem.

    PubMed

    Scherrer, Alexander; Schwidde, Ilka; Dinges, Andreas; Rüdiger, Patrick; Kümmel, Sherko; Küfer, Karl-Heinz

    2015-09-01

    Breast cancer is the most common carcinosis with the largest number of mortalities in women. Its therapy comprises a wide spectrum of different treatment modalities a breast oncologist decides about for the individual patient case. These decisions happen according to medical guide lines, current scientific publications and experiences acquired in former cases. Clinical decision making therefore involves the time-consuming search for possible therapy options and their thorough testing for applicability to the current patient case.This research work addresses breast cancer therapy planning as a multi-criteria sequential decision making problem. The approach is based on a data model for patient cases with therapy descriptions and a mathematical notion for therapeutic relevance of medical information. This formulation allows for a novel decision support concept, which targets at eliminating observed weaknesses in clinical routine of breast cancer therapy planning.

  20. The Communications Skills as The One Side of Capability to Make Plans

    NASA Astrophysics Data System (ADS)

    Kiriyama, Satoshi; Konishi, Masaki; Hanabusa, Takao

    In the Center for Innovation and Creativity Development, we have planned students' project activities and have found out various educational subjects by guiding the members of projects. Particularly, we have regarded “raising the capability to make plans” as an essential subject. The lack of the capability causes various problems in project activities, and communications skills are also affected. This tendency is observed in all the projects, though the students of science and liberal arts have participated in the projects. We have taken the measure against students' lack of the capability, and have opened a course of liberal arts new for the freshmen based on the knowledge. We will introduce the measure in the lecture and discuss the communications skills as the one side of capability to make plans.

  1. Long-term planning and decision-making among midlife and older gay men and lesbians.

    PubMed

    Hash, Kristina M; Netting, F Ellen

    2007-01-01

    This article examines the issues of long-term planning and decision-making among midlife and older gay men and lesbian caregivers. Using a qualitative methodology, in-depth interviews were conducted with 19 gay men and lesbians over 50. Participants reported on their long-term planning and decision-making processes. All but four persons reported that their partners had advance directives, but the majority of caregivers did not have advance directives for themselves. Concerns about informal family dynamics and interactions with formal systems were expressed, along with financial and ownership issues. It is important for social workers to intervene across individual, organizational, and community levels in advocacy for the needs of older gay men and lesbian clients.

  2. Visualization support for risk-informed decision making when planning and managing software developments

    NASA Technical Reports Server (NTRS)

    Feather, Martin S.; Kiper, James D.; Menzies, Tim

    2005-01-01

    Key decisions are made in the early stages of planning and management of software developments. The information basis for these decisions is often a mix of analogy with past developments, and the best judgments of domain experts. Visualization of this information can support to such decision making by clarifying the status of the information and yielding insights into the ramifications of that information vis-a-vis decision alternatives.

  3. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false How do I make my draft materials separation plan available to the public? 60.1070 Section 60.1070 Protection of Environment ENVIRONMENTAL... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation...

  4. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false How do I make my draft materials separation plan available to the public? 60.1070 Section 60.1070 Protection of Environment ENVIRONMENTAL... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation...

  5. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false How do I make my draft materials separation plan available to the public? 60.1070 Section 60.1070 Protection of Environment ENVIRONMENTAL... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation...

  6. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false How do I make my draft materials separation plan available to the public? 60.1070 Section 60.1070 Protection of Environment ENVIRONMENTAL... Preconstruction Requirements: Materials Separation Plan § 60.1070 How do I make my draft materials separation...

  7. A visualization tool to support decision making in environmental and biological planning

    USGS Publications Warehouse

    Romañach, Stephanie S.; McKelvy, James M.; Conzelmann, Craig; Suir, Kevin J.

    2014-01-01

    Large-scale ecosystem management involves consideration of many factors for informed decision making. The EverVIEW Data Viewer is a cross-platform desktop decision support tool to help decision makers compare simulation model outputs from competing plans for restoring Florida's Greater Everglades. The integration of NetCDF metadata conventions into EverVIEW allows end-users from multiple institutions within and beyond the Everglades restoration community to share information and tools. Our development process incorporates continuous interaction with targeted end-users for increased likelihood of adoption. One of EverVIEW's signature features is side-by-side map panels, which can be used to simultaneously compare species or habitat impacts from alternative restoration plans. Other features include examination of potential restoration plan impacts across multiple geographic or tabular displays, and animation through time. As a result of an iterative, standards-driven approach, EverVIEW is relevant to large-scale planning beyond Florida, and is used in multiple biological planning efforts in the United States.

  8. Strategic planning decision making using fuzzy SWOT-TOPSIS with reliability factor

    NASA Astrophysics Data System (ADS)

    Mohamad, Daud; Afandi, Nur Syamimi; Kamis, Nor Hanimah

    2015-10-01

    Strategic planning is a process of decision making and action for long-term activities in an organization. The Strengths, Weaknesses, Opportunities and Threats (SWOT) analysis has been commonly used to help organizations in strategizing their future direction by analyzing internal and external environment. However, SWOT analysis has some limitations as it is unable to prioritize appropriately the multiple alternative strategic decisions. Some efforts have been made to solve this problem by incorporating Multi Criteria Decision Making (MCDM) methods. Nevertheless, another important aspect has raised concerns on obtaining the decision that is the reliability of the information. Decision makers evaluate differently depending on their level of confidence or sureness in the evaluation. This study proposes a decision making procedure for strategic planning using SWOT-TOPSIS method by incorporating the reliability factor of the evaluation based on Z-number. An example using a local authority in the east coast of Malaysia is illustrated to determine the strategic options ranking and to prioritize factors in each SWOT category.

  9. Understanding and supporting African Americans' perspectives of end-of-life care planning and decision making.

    PubMed

    Waters, C M

    2001-05-01

    Ethnicity has been found to explain some differences across ethnic groups regarding end-of-life care choices. African Americans appear to be less likely to know about advance directives and to complete them. Five community-based focus groups, consisting of 27 African Americans, were convened to explore their perspectives of end-of-life care planning and decision making. Content analysis revealed six themes: death is not an option, religiosity and end-of-life care planning is a paradox, the health care system is a microcosm of societal and historical events, a "trusted" family member or friend is the contract for life-and-death options, ethnically relevant initiatives are essential to increase advance directives participation, and people are people. These themes serve to guide health care professionals in minimizing actions that increase African Americans' mistrust of the health care system not only in end-of-life situations but also in all of health care-related interactions.

  10. Later-life planning: promoting knowledge of options and choice-making.

    PubMed

    Heller, T; Miller, A B; Hsieh, K; Sterns, H

    2000-10-01

    The effectiveness of a person-centered later-life planning training program designed to teach older adults (N = 60) with mental retardation about later-life planning issues and increase their participation in choice-making was examined. Using quantitative data analyses, we assessed the impact of the program on intervention and control groups. Results indicated that the intervention group gained more knowledge of concepts in the curriculum and made more choices over time than did the control group. The wide variety of goals that participants set were examined through qualitative analyses; 87% of the participants met or partially met their goals. Information on the supports and barriers to meeting goals is provided.

  11. Young adults' decision making surrounding heavy drinking: a multi-staged model of planned behaviour.

    PubMed

    Northcote, Jeremy

    2011-06-01

    This paper examines the real life contexts in which decisions surrounding heavy drinking are made by young adults (that is, on occasions when five or more alcoholic drinks are consumed within a few hours). It presents a conceptual model that views such decision making as a multi-faceted and multi-staged process. The mixed method study draws on purposive data gathered through direct observation of eight social networks consisting of 81 young adults aged between 18 and 25 years in Perth, Western Australia, including in-depth interviews with 31 participants. Qualitative and some basic quantitative data were gathered using participant observation and in-depth interviews undertaken over an eighteen month period. Participants explained their decision to engage in heavy drinking as based on a variety of factors. These elements relate to socio-cultural norms and expectancies that are best explained by the theory of planned behaviour. A framework is proposed that characterises heavy drinking as taking place in a multi-staged manner, with young adults having: 1. A generalised orientation to the value of heavy drinking shaped by wider influences and norms; 2. A short-term orientation shaped by situational factors that determines drinking intentions for specific events; and 3. An evaluative orientation shaped by moderating factors. The value of qualitative studies of decision making in real life contexts is advanced to complement the mostly quantitative research that dominates research on alcohol decision making. PMID:21632161

  12. Young adults' decision making surrounding heavy drinking: a multi-staged model of planned behaviour.

    PubMed

    Northcote, Jeremy

    2011-06-01

    This paper examines the real life contexts in which decisions surrounding heavy drinking are made by young adults (that is, on occasions when five or more alcoholic drinks are consumed within a few hours). It presents a conceptual model that views such decision making as a multi-faceted and multi-staged process. The mixed method study draws on purposive data gathered through direct observation of eight social networks consisting of 81 young adults aged between 18 and 25 years in Perth, Western Australia, including in-depth interviews with 31 participants. Qualitative and some basic quantitative data were gathered using participant observation and in-depth interviews undertaken over an eighteen month period. Participants explained their decision to engage in heavy drinking as based on a variety of factors. These elements relate to socio-cultural norms and expectancies that are best explained by the theory of planned behaviour. A framework is proposed that characterises heavy drinking as taking place in a multi-staged manner, with young adults having: 1. A generalised orientation to the value of heavy drinking shaped by wider influences and norms; 2. A short-term orientation shaped by situational factors that determines drinking intentions for specific events; and 3. An evaluative orientation shaped by moderating factors. The value of qualitative studies of decision making in real life contexts is advanced to complement the mostly quantitative research that dominates research on alcohol decision making.

  13. Modelling the learning of biomechanics and visual planning for decision-making of motor actions.

    PubMed

    Cos, Ignasi; Khamassi, Mehdi; Girard, Benoît

    2013-11-01

    Recent experiments showed that the bio-mechanical ease and end-point stability associated to reaching movements are predicted prior to movement onset, and that these factors exert a significant influence on the choice of movement. As an extension of these results, here we investigate whether the knowledge about biomechanical costs and their influence on decision-making are the result of an adaptation process taking place during each experimental session or whether this knowledge was learned at an earlier stage of development. Specifically, we analysed both the pattern of decision-making and its fluctuations during each session, of several human subjects making free choices between two reaching movements that varied in path distance (target relative distance), biomechanical cost, aiming accuracy and stopping requirement. Our main result shows that the effect of biomechanics is well established at the start of the session, and that, consequently, the learning of biomechanical costs in decision-making occurred at an earlier stage of development. As a means to characterise the dynamics of this learning process, we also developed a model-based reinforcement learning model, which generates a possible account of how biomechanics may be incorporated into the motor plan to select between reaching movements. Results obtained in simulation showed that, after some pre-training corresponding to a motor babbling phase, the model can reproduce the subjects' overall movement preferences. Although preliminary, this supports that the knowledge about biomechanical costs may have been learned in this manner, and supports the hypothesis that the fluctuations observed in the subjects' behaviour may adapt in a similar fashion.

  14. Modelling the learning of biomechanics and visual planning for decision-making of motor actions.

    PubMed

    Cos, Ignasi; Khamassi, Mehdi; Girard, Benoît

    2013-11-01

    Recent experiments showed that the bio-mechanical ease and end-point stability associated to reaching movements are predicted prior to movement onset, and that these factors exert a significant influence on the choice of movement. As an extension of these results, here we investigate whether the knowledge about biomechanical costs and their influence on decision-making are the result of an adaptation process taking place during each experimental session or whether this knowledge was learned at an earlier stage of development. Specifically, we analysed both the pattern of decision-making and its fluctuations during each session, of several human subjects making free choices between two reaching movements that varied in path distance (target relative distance), biomechanical cost, aiming accuracy and stopping requirement. Our main result shows that the effect of biomechanics is well established at the start of the session, and that, consequently, the learning of biomechanical costs in decision-making occurred at an earlier stage of development. As a means to characterise the dynamics of this learning process, we also developed a model-based reinforcement learning model, which generates a possible account of how biomechanics may be incorporated into the motor plan to select between reaching movements. Results obtained in simulation showed that, after some pre-training corresponding to a motor babbling phase, the model can reproduce the subjects' overall movement preferences. Although preliminary, this supports that the knowledge about biomechanical costs may have been learned in this manner, and supports the hypothesis that the fluctuations observed in the subjects' behaviour may adapt in a similar fashion. PMID:23973913

  15. A study of decision-making behavior of aircraft pilots deviating from a planned flight

    NASA Technical Reports Server (NTRS)

    Flather, G. W., II; Giffin, W. C.; Rockwell, T. H.

    1981-01-01

    This paper outlines an investigation into the worth structures of pilots facing a deviation from a planned flight. A 'paper and pencil' simulation was used to frame the situation into which pilots interjected their own decision making skills in a simple ranking of candidate diversion airports with varying locational, navigational aid, radar and weather attributes. Using the conjoint measurement technique, attribute worth functions of 30 pilots were constructed. It was discovered that systematic differences in the worth functions of the pilots did not occur as a result of dividing the pilot sample according to any measure of flight hour experience. However, differences were found when the pilot sample was grouped according to grade of pilot certificate, type of pilot training, and type of flying most commonly done.

  16. Strategic Planning, Management and Decision Making. AAHE-ERIC/Higher Education Research Report No. 9, 1981.

    ERIC Educational Resources Information Center

    Cope, Robert G.

    Recent applications of the strategic planning approach in colleges and universities and techniques necessary for its application are reviewed. In addition, the intellectual roots of strategic planning are traced, and strategic planning is defined and contrasted with long-range planning. It is suggested that strategic planning addresses the total…

  17. 78 FR 29157 - Certain Digital Models, Digital Data, and Treatment Plans for Use, in Making Incremental Dental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Certain Digital Models, Digital Data, and Treatment Plans for Use, in Making Incremental Dental Positioning Adjustment Appliances Made Therefrom, and Methods of Making the Same Investigation No. 337-...

  18. Analyzing and sense making of human factors in the Malaysian radiation and nuclear emergency planning framework

    NASA Astrophysics Data System (ADS)

    Hamid, A. H. A.; Rozan, M. Z. A.; Deris, S.; Ibrahim, R.; Abdullah, W. S. W.; Rahman, A. A.; Yunus, M. N. M.

    2016-01-01

    The evolution of current Radiation and Nuclear Emergency Planning Framework (RANEPF) simulator emphasizes on the human factors to be analyzed and interpreted according to the stakeholder's tacit and explicit knowledge. These human factor criteria are analyzed and interpreted according to the "sense making theory" and Disaster Emergency Response Management Information System (DERMIS) design premises. These criteria are corroborated by the statistical criteria. In recent findings, there were no differences of distributions among the stakeholders according to gender and organizational expertise. These criteria are incrementally accepted and agreed the research elements indicated in the respective emergency planning frameworks and simulator (i.e. 78.18 to 84.32, p-value <0.05). This paper suggested these human factors criteria in the associated analyses and theoretical perspectives to be further acomodated in the future simulator development. This development is in conjunction with the proposed hypothesis building of the process factors and responses diagram. We proposed that future work which implies the additional functionality of the simulator, as strategized, condensed and concise, comprehensive public disaster preparedness and intervention guidelines, to be a useful and efficient computer simulation.

  19. 25 CFR 290.7 - Must an Indian tribe have a tribal revenue allocation plan if it is not making per capita payments?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... plan if it is not making per capita payments? 290.7 Section 290.7 Indians BUREAU OF INDIAN AFFAIRS... have a tribal revenue allocation plan if it is not making per capita payments? No, if you do not make per capita payments, you do not need to submit a tribal revenue allocation plan....

  20. 25 CFR 290.7 - Must an Indian tribe have a tribal revenue allocation plan if it is not making per capita payments?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... plan if it is not making per capita payments? 290.7 Section 290.7 Indians BUREAU OF INDIAN AFFAIRS... have a tribal revenue allocation plan if it is not making per capita payments? No, if you do not make per capita payments, you do not need to submit a tribal revenue allocation plan....

  1. 25 CFR 290.7 - Must an Indian tribe have a tribal revenue allocation plan if it is not making per capita payments?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... plan if it is not making per capita payments? 290.7 Section 290.7 Indians BUREAU OF INDIAN AFFAIRS... have a tribal revenue allocation plan if it is not making per capita payments? No, if you do not make per capita payments, you do not need to submit a tribal revenue allocation plan....

  2. 25 CFR 290.7 - Must an Indian tribe have a tribal revenue allocation plan if it is not making per capita payments?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... plan if it is not making per capita payments? 290.7 Section 290.7 Indians BUREAU OF INDIAN AFFAIRS... have a tribal revenue allocation plan if it is not making per capita payments? No, if you do not make per capita payments, you do not need to submit a tribal revenue allocation plan....

  3. Role of Advance Care Planning in Proxy Decision Making Among Individuals With Dementia and Their Family Caregivers.

    PubMed

    Kwak, Jung; De Larwelle, Jessica A; Valuch, Katharine O'Connell; Kesler, Toni

    2016-01-01

    Health care proxies make important end-of-life decisions for individuals with dementia. A cross-sectional survey was conducted to examine the role of advance care planning in proxy decision making for 141 individuals with cognitive impairment, Alzheimer's disease, or other types of dementia. Proxies who did not know the preferences of individuals with dementia for life support treatments reported greater understanding of their values. Proxies of individuals with dementia who did not want life support treatments anticipated receiving less support and were more uncertain in decision making. The greater knowledge proxies had about dementia trajectory, family support, and trust of physicians, the more informed, clearer, and less uncertain they were in decision making. In addition to advance care planning, multiple factors influence proxy decision making, which should be considered in developing interventions and future research to support informed decision making for individuals with dementia and their families.

  4. City-Level Energy Decision Making. Data Use in Energy Planning, Implementation, and Evaluation in U.S. Cities

    SciTech Connect

    Aznar, Alexandra; Day, Megan; Doris, Elizabeth; Mathur, Shivani; Donohoo-Vallett, Paul

    2015-07-08

    The Cities-LEAP technical report, City-Level Energy Decision Making: Data Use in Energy Planning, Implementation, and Evaluation in U.S. Cities, explores how a sample of cities incorporates data into making energy-related decisions. This report provides the foundation for forthcoming components of the Cities-LEAP project that will help cities improve energy decision making by mapping specific city energy or climate policies and actions to measurable impacts and results.

  5. Using Many-Objective Optimization and Robust Decision Making to Identify Robust Regional Water Resource System Plans

    NASA Astrophysics Data System (ADS)

    Matrosov, E. S.; Huskova, I.; Harou, J. J.

    2015-12-01

    Water resource system planning regulations are increasingly requiring potential plans to be robust, i.e., perform well over a wide range of possible future conditions. Robust Decision Making (RDM) has shown success in aiding the development of robust plans under conditions of 'deep' uncertainty. Under RDM, decision makers iteratively improve the robustness of a candidate plan (or plans) by quantifying its vulnerabilities to future uncertain inputs and proposing ameliorations. RDM requires planners to have an initial candidate plan. However, if the initial plan is far from robust, it may take several iterations before planners are satisfied with its performance across the wide range of conditions. Identifying an initial candidate plan is further complicated if many possible alternative plans exist and if performance is assessed against multiple conflicting criteria. Planners may benefit from considering a plan that already balances multiple performance criteria and provides some level of robustness before the first RDM iteration. In this study we use many-objective evolutionary optimization to identify promising plans before undertaking RDM. This is done for a very large regional planning problem spanning the service area of four major water utilities in East England. The five-objective optimization is performed under an ensemble of twelve uncertainty scenarios to ensure the Pareto-approximate plans exhibit an initial level of robustness. New supply interventions include two reservoirs, one aquifer recharge and recovery scheme, two transfers from an existing reservoir, five reuse and five desalination schemes. Each option can potentially supply multiple demands at varying capacities resulting in 38 unique decisions. Four candidate portfolios were selected using trade-off visualization with the involved utilities. The performance of these plans was compared under a wider range of possible scenarios. The most balanced plan was then submitted into the vulnerability

  6. Care planning and decision-making in teams in Swedish elderly care: a study of interprofessional collaboration and professional boundaries.

    PubMed

    Duner, Anna

    2013-05-01

    In front-line practice, joint working between different professionals in health/social care and rehabilitation is regarded as a means to reach a comprehensive assessment of the needs of the older care recipients, leading to decisions on appropriate care and services. The aim of this study was to examine professional collaboration and professional boundaries in interprofessional care planning teams. Two different care planning teams were studied, one performing care planning in the homes of older individuals and the other performing care planning for older people in hospital wards. The empirical data consisted of audio-recorded care planning meetings and interviews with the professionals in the teams. The integration between the professionals involved was most noticeable in the investigation and assessment phase, while it was lower in the planning phase and almost non-existent in decision-making. The home care planning team tended to work in a more integrated manner than the discharge planning team. The importance of clarifying the roles of all professions concerned with needs assessment and care planning for older people became evident in this study.

  7. From Visions to Success via Strategic Planning. Net Confidence in Making Budget and Other Decisions.

    ERIC Educational Resources Information Center

    Chopra, Raj K.

    1988-01-01

    A well-conceived and concisely written plan can become an important vehicle to meet challenges and gain citizens' confidence in a school system. Effective strategic planning requires community involvement, husbanding of resources, and a clear sense of timing. (TE)

  8. Challenges of Training Pre-Retirees to Make Sound Financial Planning Decisions.

    ERIC Educational Resources Information Center

    Hershey, Douglas A.; Walsh, David A.; Brougham, Ruby; Carter, Stephen; Farrell, Alicia

    1998-01-01

    Adults ages 55-65 (n=23) were asked to provide solutions to retirement planning scenarios before and after attending financial planning training. Although their knowledge increased significantly, the overall quality of their decisions did not improve after training. (SK)

  9. Making Resources Matter: A Systematic Approach to Developing the Local Consolidated Plan. Modules One [to] Ten.

    ERIC Educational Resources Information Center

    Bowman, Diana; Williams, Jean

    This guide is designed to help school districts develop a consolidated plan for programs and resources. It outlines the importance of generating a consolidated plan to reduce duplication, identify children's needs, and coordinate funds from various programs. Consisting of 10 modules, the guide addresses all components of the planning process and…

  10. Making sense of the change in how Medicare Advantage plans are paid.

    PubMed

    Gold, Marsha

    2013-05-01

    The Affordable Care Act has altered payment policy for private Medicare Advantage (MA) plans, with the goal of lowering costs closer to the level in traditional Medicare. Using newly available information on 2009 MA plan costs, this analysis com­pares plans' estimates of per capita costs for providing Parts A and B benefits to their enrollees, on a risk-adjusted basis, against what government data show to be the same costs for traditional Medicare program beneficiaries residing in the same county. It finds that on average, risk-adjusted MA plan costs were 4 percent higher than traditional Medicare costs (104%). Among plan types, only HMOs had lower average costs than traditional Medicare. Among local PPOs and private fee-for service plans, over 75 percent had costs exceeding those in traditional Medicare. The wide variation seen in MA plan costs relative to traditional Medicare suggests there is room for greater efficiency in care delivery.

  11. Team Teaching in the Elementary School: A Long-Term Qualitative Study of Teacher Planning and Decision-Making.

    ERIC Educational Resources Information Center

    Riley, John F.

    This study examined collaborative planning and decision making in a grade level team of elementary teachers during team meetings. Fourteen teachers in a suburban district participated over 3 years. Participants were predominantly white and female and ranged from first-year to experienced teachers. Teachers were observed during regular weekly team…

  12. 78 FR 46610 - Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental Dental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... (``Align''), on March 1, 2012, as corrected on March 22, 2012. 77 FR 20648 (April 5, 2012). The complaint... Presidential Memorandum of July 21, 2005, 70 FR 43251 (July 26, 2005). During this period, the subject articles... COMMISSION Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental...

  13. 78 FR 46611 - Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental Dental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... (``Align''), on March 1, 2012, as corrected on March 22, 2012. 77 FR 20648 (April 5, 2012). The complaint... Presidential Memorandum of July 21, 2005, 70 FR 43251 (July 26, 2005). During this period, the subject articles... COMMISSION Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental...

  14. A STUDY TO DETERMINE HOW COUNSELING PROCEDURES CAN BE USED TO HELP STUDENTS MAKE DECISIONS AND PLANS MORE EFFECTIVELY.

    ERIC Educational Resources Information Center

    KRUMBOLTZ, JOHN D.; AND OTHERS

    COUNSELING PROCEDURES DERIVED FROM RESEARCH IN SOCIAL LEARNING WERE EXPERIMENTALLY TESTED. PROCEDURES WERE USED BY COUNSELORS TO ASSIST STUDENTS IN LEARNING HOW TO MAKE PLANS AND DECISIONS MORE EFFECTIVELY. SPECIFICALLY, THIS STUDY TESTED THE RELATIVE EFFECT OF STUDENT SOCIAL MODELS, CHARACTERIZED BY VARYING DEGREES OF ATHLETIC, SOCIAL, AND…

  15. Utilizing Shared Decision Making in Developing a Computer Technology Comprehensive Plan for a Small, Rural, K-12 Campus.

    ERIC Educational Resources Information Center

    Crumley, William H.

    This practicum was designed to utilize a shared decision making (SDM) committee model as a mechanism through which a long-range, comprehensive computer technology plan would be developed for a Jackman (Maine) school system. On-site research coupled with an extensive review of current literature produced a finding that long-range technology…

  16. 25 CFR 290.7 - Must an Indian tribe have a tribal revenue allocation plan if it is not making per capita payments?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... if it is not making per capita payments? 290.7 Section 290.7 Indians BUREAU OF INDIAN AFFAIRS... have a tribal revenue allocation plan if it is not making per capita payments? No, if you do not make per capita payments, you do not need to submit a tribal revenue allocation plan....

  17. Making the case for succession planning: who's on deck in your organization?

    PubMed

    Laframboise, Lorrie E

    2011-06-01

    In Canada, the nursing shortage is all encompassing, and nurse leaders are needed from the bedside to the boardroom. Healthcare organizations and the nursing profession lag behind the corporate sector in development of strategic leadership succession planning. Contemporary nurse leaders will require all the knowledge, skills, attitudes and competencies their predecessors can provide. Effective leadership development and succession planning will provide a climate that is conducive to the transfer of that knowledge. Providing leadership development opportunities within the context of succession planning will assist nurses to develop and nurture the leader within. A definitive strategic succession plan may mean the difference between success and failure for nurses and their organizations.

  18. Planning versus action: Different decision-making processes predict plans to change one's diet versus actual dietary behavior.

    PubMed

    Kiviniemi, Marc T; Brown-Kramer, Carolyn R

    2015-05-01

    Most health decision-making models posit that deciding to engage in a health behavior involves forming a behavioral intention which then leads to actual behavior. However, behavioral intentions and actual behavior may not be functionally equivalent. Two studies examined whether decision-making factors predicting dietary behaviors were the same as or distinct from those predicting intentions. Actual dietary behavior was proximally predicted by affective associations with the behavior. By contrast, behavioral intentions were predicted by cognitive beliefs about behaviors, with no contribution of affective associations. This dissociation has implications for understanding individual regulation of health behaviors and for behavior change interventions.

  19. Planning versus action: Different decision-making processes predict plans to change one's diet versus actual dietary behavior.

    PubMed

    Kiviniemi, Marc T; Brown-Kramer, Carolyn R

    2015-05-01

    Most health decision-making models posit that deciding to engage in a health behavior involves forming a behavioral intention which then leads to actual behavior. However, behavioral intentions and actual behavior may not be functionally equivalent. Two studies examined whether decision-making factors predicting dietary behaviors were the same as or distinct from those predicting intentions. Actual dietary behavior was proximally predicted by affective associations with the behavior. By contrast, behavioral intentions were predicted by cognitive beliefs about behaviors, with no contribution of affective associations. This dissociation has implications for understanding individual regulation of health behaviors and for behavior change interventions. PMID:25903243

  20. Information Technology: Making It All Fit. Track I: Policy and Planning.

    ERIC Educational Resources Information Center

    CAUSE, Boulder, CO.

    Seven papers from the 1988 CAUSE conference's Track I, Policy and Planning, are presented. They include: "Developing a Strategic Plan for Academic Computing" (Arthur S. Gloster II); "New Technologies Are Presenting a Crisis for Middle Management" (M. Lewis Temares and Ruben Lopez); "An Information Utility: The Light, Gas, and Water for Information…

  1. Ethical Decision Making in Academic Dishonesty with Application of Modified Theory of Planned Behavior: A Review

    ERIC Educational Resources Information Center

    Meng, Chan Ling; Othman, Jamilah; D'Silva, Jeffrey Lawrence; Omar, Zoharah

    2014-01-01

    This conceptual paper studies the application of the Theory of Planned Behavior (TBP) in academic dishonesty with the mediating variable of ethical ideologies. The study reviews literature on the Theory of Planned Behavior and past studies pertaining to academic dishonesty. The paper analyses the relationship of the variables of TPB on academic…

  2. Making Schools Safe for Students: Creating a Proactive School Safety Plan.

    ERIC Educational Resources Information Center

    Blauvelt, Peter D.

    This guide offers strategies for creating a proactive school safety plan that encourages parents, teachers, principals, and students to take the initiative and identify threats to school safety. It emphasizes that schools must have an active plan that addresses fights, name calling, bullying, changes in kid's behaviors, and staff who have run out…

  3. Making Community Connections: Educator Perspectives on Transition Planning for Students with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Schwartz, Karen; Mactavish, Jennifer; Lutfiyya, Zana Marie

    2006-01-01

    For students with intellectual disabilities and their families, planning for the transition from school to adult life can be a complicated process. Successful planning is sometimes made more challenging when post-school options and opportunities are not well known or understood. The purpose of this study is to seek out the perspectives of…

  4. A Study of Teacher Planning: Description and a Model of Preactive Decision Making.

    ERIC Educational Resources Information Center

    Yinger, Robert J.

    The primary objective of this study was to describe those mental processes involved in teacher planning decisions made prior to teaching. One elementary teacher's planning decisions were studied during five months of classroom instruction. Both ethnographic and information processing approaches were used to describe distinctive features of the…

  5. Making Cents Out of Solar: Put More Power Into Your Building Plans (Brochure)

    SciTech Connect

    Not Available

    2008-01-01

    This is a brochure developed specifically for residential home builders. It provides information on basic solar facts, selling tips, and important resources when incorporating solar technologies into building plans.

  6. Making Cents Out of Solar: Put More Power Into Your Building Plans

    SciTech Connect

    2008-01-01

    This is a brochure developed specifically for residential home builders. It provides information on basic solar facts, selling tips, and important resources when incorporating solar technologies into building plans.

  7. Solving complex maintenance planning optimization problems using stochastic simulation and multi-criteria fuzzy decision making

    NASA Astrophysics Data System (ADS)

    Tahvili, Sahar; Österberg, Jonas; Silvestrov, Sergei; Biteus, Jonas

    2014-12-01

    One of the most important factors in the operations of many cooperations today is to maximize profit and one important tool to that effect is the optimization of maintenance activities. Maintenance activities is at the largest level divided into two major areas, corrective maintenance (CM) and preventive maintenance (PM). When optimizing maintenance activities, by a maintenance plan or policy, we seek to find the best activities to perform at each point in time, be it PM or CM. We explore the use of stochastic simulation, genetic algorithms and other tools for solving complex maintenance planning optimization problems in terms of a suggested framework model based on discrete event simulation.

  8. Solving complex maintenance planning optimization problems using stochastic simulation and multi-criteria fuzzy decision making

    SciTech Connect

    Tahvili, Sahar; Österberg, Jonas; Silvestrov, Sergei; Biteus, Jonas

    2014-12-10

    One of the most important factors in the operations of many cooperations today is to maximize profit and one important tool to that effect is the optimization of maintenance activities. Maintenance activities is at the largest level divided into two major areas, corrective maintenance (CM) and preventive maintenance (PM). When optimizing maintenance activities, by a maintenance plan or policy, we seek to find the best activities to perform at each point in time, be it PM or CM. We explore the use of stochastic simulation, genetic algorithms and other tools for solving complex maintenance planning optimization problems in terms of a suggested framework model based on discrete event simulation.

  9. Policy-Making, Strategic Planning, and Management of Higher Education. Papers on Higher Education.

    ERIC Educational Resources Information Center

    Taylor, John; Miroiu, Adrian

    This volume is the second in a series of four publications related to a project on the creation of a Regional University Network on Governance and Management of Higher Education in South East Europe. It consists of a concise presentation of the nuts and bolts of strategic planning and management in higher education. The book takes the reader…

  10. Antecedents and Consequences of Retirement Planning and Decision-Making: A Meta-Analysis and Model

    ERIC Educational Resources Information Center

    Topa, Gabriela; Moriano, Juan Antonio; Depolo, Marco; Alcover, Carlos-Maria; Morales, J. Francisco

    2009-01-01

    In this study, meta-analytic procedures were used to examine the relationships between retirement planning, retirement decision and their antecedent and consequences. Our review of the literature generated 341 independent samples obtained from 99 primary studies with 188,222 participants. A small effect size (ES) for antecedents of retirement…

  11. The New Youth Entrepreneur: You Can Make It Happen. YESS! You. The Business Plan. Module 12.

    ERIC Educational Resources Information Center

    Kourilsky, Marilyn; And Others

    The New Youth Entrepreneur curriculum is a series of 12 youth-oriented educational modules containing instructional materials, learning activities, and checkup exercises designed to teach students key elements of entrepreneurship. This document is the twelfth module, and discusses the usefulness of a business plan for entrepreneurs starting small…

  12. Planning and Realigning a Lesson in Response to Student Contributions: Intentions and Decision Making

    ERIC Educational Resources Information Center

    Boyd, Maureen P.

    2012-01-01

    What constitutes a successful lesson? A considerable body of literature examines instructional talk; however, little attention has been directed to situations in which teacher intentions (as captured by lesson plan) are stymied by unanticipated student response and the teacher must instantaneously reevaluate and revise an intended lesson. This…

  13. Aim for Excellence: A Plan for Making Arts Education Basic in Iowa.

    ERIC Educational Resources Information Center

    Downing, Karen, Ed.; Penney, Rita, Ed.

    Art instruction in Iowa schools lacks cohesiveness and continuity. This may be due in part to the state government's commitment to local autonomy. The Iowa Department of Education does not mandate what schools must do; it only suggests and encourages. In 1986, the department published a five-year plan for the achievement of educational goals,…

  14. Community Organizations' Involvement in School Safety Planning: Does It Make a Difference in School Violence?

    ERIC Educational Resources Information Center

    Patton, Joy D.

    2011-01-01

    This study examines the relationship between school violence and involvement of community organizations in school safety planning. The study is a secondary analysis of data from the School Survey on Crime and Safety 2003-2004 (U.S. Department of Education, Institute of Education Sciences, 2006). This survey collects data on crime and safety from…

  15. Helping Students with Dyslexia and Dysgraphia Make Connections: Differentiated Instruction Lesson Plans in Reading and Writing

    ERIC Educational Resources Information Center

    Berninger, Virginia W.; Wolf, Beverly

    2009-01-01

    Students in Ginger Berninger's research studies "showed significant improvement in their reading and writing" after using these lessons--now available to teachers for the first time ever in one convenient book! A state-of-the-art set of lesson plans that can be used for differentiated instruction of students with dysgraphia, dyslexia, and OWL LD,…

  16. Choice-Making in Vocational Activities Planning: Recommendations from Job Coaches

    ERIC Educational Resources Information Center

    Cobigo, Virginie; Lachapelle, Yves; Morin, Diane

    2010-01-01

    Choice in the job seeking process may lead to increased satisfaction with the chosen job, and improve attention, performance, and motivation. Consequently, providing opportunities to express choices and interests while planning vocational activities is a key factor in achieving employment outcomes. Despite their commitment to promoting…

  17. Making the Most of Your School Site. School Buildings Planning, Design, and Construction Series No. 2.

    ERIC Educational Resources Information Center

    Odell, John H.

    A school construction guide offers key personnel in school development projects information on the complex task of master planning and construction of schools in Australia. This chapter of the guide provides advice on site selection covering selection criteria; traffic issues; and site services, such as water, power, and sewer. Additionally…

  18. Federal Policy to Local Level Decision-Making: Data Driven Education Planning in Nigeria

    ERIC Educational Resources Information Center

    Iyengar, Radhika; Mahal, Angelique R.; Felicia, Ukaegbu-Nnamchi Ifeyinwa; Aliyu, Balaraba; Karim, Alia

    2015-01-01

    This article discusses the implementation of local level education data-driven planning as implemented by the Office of the Senior Special Assistant to the President of Nigeria on the Millennium Development Goals (OSSAP-MDGs) in partnership with The Earth Institute, Columbia University. It focuses on the design and implementation of the…

  19. Improved monitoring framework for local planning in the water, sanitation and hygiene sector: From data to decision-making.

    PubMed

    Garriga, Ricard Giné; de Palencia, Alejandro Jiménez Fdez; Foguet, Agustí Pérez

    2015-09-01

    Today, a vast proportion of people still lack a simple pit latrine and a source of safe drinking water. To help end this appalling state of affairs, there is a pressing need to provide policymakers with evidences which may be the basis of effective planning, targeting and prioritization. Two major challenges often hinder this process: i) lack of reliable data to identify which areas are most in need; and ii) inadequate instruments for decision-making support. In tackling previous shortcomings, this paper proposes a monitoring framework to compile, analyze, interpret and disseminate water, sanitation and hygiene information. In an era of decentralization, where decision-making moves to local governments, we apply such framework at the local level. The ultimate goal is to develop appropriate tools for decentralized planning support. To this end, the study first implements a methodology for primary data collection, which combines the household and the waterpoint as information sources. In doing so, we provide a complete picture of the context in which domestic WASH services are delivered. Second, the collected data are analyzed to underline the emerging development challenges. The use of simple planning indicators serves as the basis to i) reveal which areas require policy attention, and to ii) identify the neediest. Third, a classification process is proposed to prioritize among various populations. Three different case studies from East and Southern African countries are presented. Results indicate that accurate and comprehensive data, if adequately exploited through simple instruments, may be the basis of effective targeting and prioritization, which are central to sector planning. The application of the proposed framework in the real world, however, is to a certain extent elusive; and we point out to conclude two specific challenges that remain unaddressed, namely the upgrade of existing decision-making processes to enhance transparency and inclusiveness, and the

  20. Improved monitoring framework for local planning in the water, sanitation and hygiene sector: From data to decision-making.

    PubMed

    Garriga, Ricard Giné; de Palencia, Alejandro Jiménez Fdez; Foguet, Agustí Pérez

    2015-09-01

    Today, a vast proportion of people still lack a simple pit latrine and a source of safe drinking water. To help end this appalling state of affairs, there is a pressing need to provide policymakers with evidences which may be the basis of effective planning, targeting and prioritization. Two major challenges often hinder this process: i) lack of reliable data to identify which areas are most in need; and ii) inadequate instruments for decision-making support. In tackling previous shortcomings, this paper proposes a monitoring framework to compile, analyze, interpret and disseminate water, sanitation and hygiene information. In an era of decentralization, where decision-making moves to local governments, we apply such framework at the local level. The ultimate goal is to develop appropriate tools for decentralized planning support. To this end, the study first implements a methodology for primary data collection, which combines the household and the waterpoint as information sources. In doing so, we provide a complete picture of the context in which domestic WASH services are delivered. Second, the collected data are analyzed to underline the emerging development challenges. The use of simple planning indicators serves as the basis to i) reveal which areas require policy attention, and to ii) identify the neediest. Third, a classification process is proposed to prioritize among various populations. Three different case studies from East and Southern African countries are presented. Results indicate that accurate and comprehensive data, if adequately exploited through simple instruments, may be the basis of effective targeting and prioritization, which are central to sector planning. The application of the proposed framework in the real world, however, is to a certain extent elusive; and we point out to conclude two specific challenges that remain unaddressed, namely the upgrade of existing decision-making processes to enhance transparency and inclusiveness, and the

  1. An Analysis of Large-Scale Writing Assessments in Canada (Grades 5-8)

    ERIC Educational Resources Information Center

    Peterson, Shelley Stagg; McClay, Jill; Main, Kristin

    2011-01-01

    This paper reports on an analysis of large-scale assessments of Grades 5-8 students' writing across 10 provinces and 2 territories in Canada. Theory, classroom practice, and the contributions and constraints of large-scale writing assessment are brought together with a focus on Grades 5-8 writing in order to provide both a broad view of…

  2. Strategic foresight: how planning for the unpredictable can improve environmental decision-making.

    PubMed

    Cook, Carly N; Inayatullah, Sohail; Burgman, Mark A; Sutherland, William J; Wintle, Brendan A

    2014-09-01

    Advanced warning of potential new opportunities and threats related to biodiversity allows decision-makers to act strategically to maximize benefits or minimize costs. Strategic foresight explores possible futures, their consequences for decisions, and the actions that promote more desirable futures. Foresight tools, such as horizon scanning and scenario planning, are increasingly used by governments and business for long-term strategic planning and capacity building. These tools are now being applied in ecology, although generally not as part of a comprehensive foresight strategy. We highlight several ways foresight could play a more significant role in environmental decisions by: monitoring existing problems, highlighting emerging threats, identifying promising new opportunities, testing the resilience of policies, and defining a research agenda.

  3. Family development: a functional choice-making approach based on the national family planning program. Summary.

    PubMed

    Kong, S K; Cho, A J; Kim, E S

    1990-12-01

    Family planning in Korea has contributed to below replacement level fertility. As a consequence, the direction of family planning needs to be changed to a quality rather than a quantity-oriented system. The emphasis should be on a family development: maternal and child health and family welfare. 3 future directions have been identified in terms of basic program service, focus on overall health, and expansion of scope. The basic objective providing information and affordable contraceptive supplies for new clients -- should remain. The service delivery can be improved and the incidence of induced abortion can be reduced. Focusing on the overall health status of family members contributes to the quality of life of the population. Infectious diseases no longer predominate, but the chronic diseases that do can be prevented with good daily health practices. These practices include sound dietary habits and regular exercise. If housewives are reduced, a comprehensive home health care system can developed. Community health practitioners (CHPs) would support the housewives. Finally, family welfare programs should be added to traditional family planning programs. Changing values and complicated roles create problems in family life. Role development for women and the elderly is another function served by a family welfare program. Therapy and education programs are a viable solution. Mother's clubs, senior citizens' schools, and neighborhood or village meetings are community institutions which could serve as educational forums to prevent family problems. For more entrenched problems, therapy is available through professional counseling services. This expanded and comprehensive health and welfare role of projected family planning programs serves to improve the quality of life as well as improving fertility control. This can be accomplished with the active participation of housewives and CHPs with professional help.

  4. Decision making, procedural compliance, and outcomes definition in U.S. forest service planning processes

    SciTech Connect

    Stern, Marc J.; Predmore, S. Andrew

    2011-04-15

    The National Environmental Policy Act (NEPA) dictates a process of analyzing and disclosing the likely impacts of proposed agency actions on the human environment. This study addresses two key questions related to NEPA implementation in the U.S. Forest Service: 1) how do Interdisciplinary (ID) team leaders and decision makers conceptualize the outcomes of NEPA processes? And 2), how does NEPA relate to agency decision making? We address these questions through two separate online surveys that posed questions about recently completed NEPA processes - the first with the ID team leaders tasked with carrying out the processes, and the second with the line officers responsible for making the processes' final decisions. Outcomes of NEPA processes include impacts on public relations, on employee morale and team functioning, on the achievement of agency goals, and on the achievement of NEPA's procedural requirements (disclosure) and substantive intent (minimizing negative environmental impacts). Although both tended to view public relations outcomes as important, decision makers' perceptions of favorable outcomes were more closely linked to the achievement of agency goals and process efficiency than was the case for ID team leaders. While ID team leaders' responses suggest that they see decision making closely integrated with the NEPA process, decision makers more commonly decoupled decision making from the NEPA process. These findings suggest a philosophical difference between ID team leaders and decision makers that may pose challenges for both the implementation and the evaluation of agency NEPA. We discuss the pros and cons of integrating NEPA with decision making or separating the two. We conclude that detaching NEPA from decision making poses greater risks than integrating them.

  5. Students' Ethical Decision-Making in an Information Technology Context: A Theory of Planned Behavior Approach

    ERIC Educational Resources Information Center

    Riemenschneider, Cynthia K.; Leonard, Lori N. K.; Manly, Tracy S.

    2011-01-01

    Business educators have increased the focus on ethics in the classroom. In order for students to become ethical professionals, they must first be held to an ethical standard as students. As information technology continues to permeate every aspect of students' lives, it becomes increasingly important to understand student decision-making in this…

  6. Strategic enterprise resource planning in a health-care system using a multicriteria decision-making model.

    PubMed

    Lee, Chang Won; Kwak, N K

    2011-04-01

    This paper deals with strategic enterprise resource planning (ERP) in a health-care system using a multicriteria decision-making (MCDM) model. The model is developed and analyzed on the basis of the data obtained from a leading patient-oriented provider of health-care services in Korea. Goal criteria and priorities are identified and established via the analytic hierarchy process (AHP). Goal programming (GP) is utilized to derive satisfying solutions for designing, evaluating, and implementing an ERP. The model results are evaluated and sensitivity analyses are conducted in an effort to enhance the model applicability. The case study provides management with valuable insights for planning and controlling health-care activities and services. PMID:20703564

  7. Strategic enterprise resource planning in a health-care system using a multicriteria decision-making model.

    PubMed

    Lee, Chang Won; Kwak, N K

    2011-04-01

    This paper deals with strategic enterprise resource planning (ERP) in a health-care system using a multicriteria decision-making (MCDM) model. The model is developed and analyzed on the basis of the data obtained from a leading patient-oriented provider of health-care services in Korea. Goal criteria and priorities are identified and established via the analytic hierarchy process (AHP). Goal programming (GP) is utilized to derive satisfying solutions for designing, evaluating, and implementing an ERP. The model results are evaluated and sensitivity analyses are conducted in an effort to enhance the model applicability. The case study provides management with valuable insights for planning and controlling health-care activities and services.

  8. Family planning and contraceptive decision-making by economically disadvantaged, African-American women

    PubMed Central

    Hodgson, Eric J.; Collier, Charlene; Hayes, Laura; Curry, Leslie; Fraenkel, Liana

    2013-01-01

    Background Significant racial disparities exist in the US unplanned pregnancy rate. We conducted a qualitative study using the theory of planned behavior as a framework to describe how low-income, African-American women approach family planning. Study Design Structured focus groups were held with adult, low-income, non-pregnant, African-American women in Connecticut. Data were collected using a standardized discussion guide, and audio-taped and transcribed. Four, independent researchers coded the transcripts using the constant comparative method. Codes were organized into over-arching themes. Results Contraceptive knowledge was limited with formal education often occurring after sexual debut. Attitudes about contraception were overtly negative with method effectiveness being judged by the experience of side effects. Family and friends strongly influence contraceptive decisions while male partners are primarily seen as a barrier. Contraceptive pills are perceived as readily accessible although compliance is considered a barrier. Conclusions Contraception education should occur before sexual debut, should involve trusted family and community members, and should positively frame issues in terms of achieving life goals. PMID:23177266

  9. Environmental vulnerability indicators for environmental planning and decision-making: guidelines and applications.

    PubMed

    Villa, Ferdinando; McLeod, Helena

    2002-03-01

    Environmental decision-making and policy-making at all levels refers necessarily to synthetic, approximate quantification of environmental properties such as vulnerability, conservation status, and ability to recover after perturbation. Knowledge of such properties is essential to informed decision-making, but their definition is controversial and their precise characterization requires investments in research, modeling, and data collection that are only possible in the most developed countries. Environmental agencies and governments worldwide have increasingly requested numerical quantification or semiquantitative ranking of such attributes at the ecosystem, landscape, and country level. We do not have a theory to guide their calculation, in general or specific contexts, particularly with the amount of resources usually available in such cases. As a result, these measures are often calculated with little scientific justification and high subjectivity, and such doubtful approximations are used for critical decision-making. This problem applies particularly to countries with weak economies, such as small island states, where the most precious environmental resources are often concentrated. This paper discusses frameworks for a "least disappointing," approximate quantification of environmental vulnerability. After a review of recent research and recent attempts to quantify environmental vulnerability, we discuss models and theoretical frameworks for obtaining an approximate, standardizable vulnerability indicator of minimal subjectivity and maximum generality. We also discuss issues of empirical testing and comparability between indicators developed for different environments. To assess the state of the art, we describe an independent ongoing project developed in the South Pacific area and aimed to the comparative evaluation of the vulnerability of arbitrary countries. PMID:11830764

  10. Processable, high temperature polymers from 1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene and bis-dienes

    NASA Technical Reports Server (NTRS)

    Meador, Mary Ann B.

    1988-01-01

    1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene reacts with various anthracene end-capped polyimide oligomers to form Diels-Alder cycloaddition copolymers. The polymers are soluble in common organic solvents, and have molecular weights of approximately 21,000 to 32,000. These resins exhibit lower weight loss in air than in nitrogen. This is suggested to be due to dehydration (loss of water ranges from 2 to 5 percent) at temperatures of 390 to 400 C to give thermooxidatively stable pentiptycene units along the polymer backbone. Because of their high softening points and good thermooxidative stability, the polymers have potential as processable, matrix resins for high temperature composite applications.

  11. Addition polymers from 1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene and Bis-dienes: Processable resins for high temperature application

    NASA Technical Reports Server (NTRS)

    Meador, Mary Ann B.

    1987-01-01

    1,4,5,8-Tetrahydro-1,4;5,8-diepoxyanthracene reacts with various anthracene endcapped polyimide oligomers to form Diels-Alder cycloaddition copolymers. The polymers are soluble in common organic solvents, and have molecular weights of approximately 21,000 to 32,000. Interestingly, these resins appear to be more stable in air then in nitrogen. This is shown to be due to a unique dehydration (loss of water ranges from 2 to 5 percent) at temperatures of 390 to 400 C to give thermo-oxidatively stable pentiptycene units along the polymer backbone. Because of their high softening points and good thermo-oxidative stability, the polymers have potential as processible, matrix resins for high temperature composite applications.

  12. A social-economic-engineering combined framework for decision making in water resources planning

    NASA Astrophysics Data System (ADS)

    Chung, E. S.; Lee, K. S.

    2008-10-01

    This study presents a new methodology not only to evaluate willingness to pays (WTPs) for the improvement of hydrological vulnerability using a choice experiment (CE) method but also to do a cost-benefit analysis (CBA) of some feasible alternatives combing the derived WTPs with an alternative evaluation index (AEI). The hydrological vulnerability consists of potential streamflow depletion (PSD), and potential water quality deterioration (PWQD) and can be quantified using a multi-criteria decision making technique and pressure-state-response (PSR) framework. PSD and PWQD not only provide survey respondents with sufficient site-specific information to avoid scope sensitivity in a choice experiment but also support the standard of dividing the study watershed into six sub-regions for site-fitted management. Therefore CE was applied to six regions one after the other, in order to determine WTPs for improvements on hydrological vulnerability considering the characteristics which are vulnerability, location, and preferences with regard to management objectives. The AEI was developed to prioritize the feasible alternatives using a continuous water quantity/quality simulation model as well as multi-criteria decision making techniques. All criteria for alternative performance were selected based on a driver-pressures-state-impact-response (DPSIR) framework, and their weights were estimated using an Analytic Hierarchy Process (AHP). In addition, the AEI that reflects on residents' preference with regard to management objectives was proposed in order to incite the stakeholder to participate in the decision making process. Finally, the economic values of each alternative are estimated by a newly developed method which combines the WTPs for improvements on hydrologic vulnerability with the AEI. This social-economic-engineering combined framework can provide the decision makers with more specific information as well as decrease the uncertainty of the CBA.

  13. Planning Protective Action Decision-Making: Evacuate or Shelter-in-Place

    SciTech Connect

    Sorensen, J.H.

    2002-08-30

    Appropriate protective action recommendations or decisions (PARs/PADs) are needed to achieve maximum protection of a population at risk. The factors that affect protective action decisions are complex but fairly well documented. Protective action decisions take into account population distributions, projected or actual exposure to a chemical substance, availability of adequate shelters, evacuation time estimates, and other relevant factors. To choose in-place sheltering, there should be a reasonable assurance that the movement of people beyond their residence, workplace, or school will endanger the health and safety of the public more so than allowing them to remain in place. The decision to evacuate the public should be based on the reasonable assurance that the movement of people to an area outside of an affected area is in the best interest of their health and safety, and is of minimal risk to them. In reality, an evacuation decision is also a resource-dependent decision. The availability of transportation and other resources, including shelters, may factor heavily in the protective action decision-making process. All strategies to protect the health and safety of the public from a release of hazardous chemicals are explicitly considered during emergency decision making. Each institutional facility (such as hospitals, schools, day care centers, correctional facilities, assisted living facilities or nursing homes) in the community should be considered separately to determine what special protective actions may be necessary. Deciding whether to evacuate or to shelter-in-place is one of the most important questions facing local emergency planners responding to a toxic chemical release. That such a complex decision with such important potential consequences must be made with such urgency places tremendous responsibility on the planners and officials involved. Researchers have devoted considerable attention to the evacuation/shelter-in-place protection decision

  14. Do Survivorship Care Plans Make a Difference? A Primary Care Provider Perspective

    PubMed Central

    Shalom, Marina Mor; Hahn, Erin E.; Casillas, Jacqueline; Ganz, Patricia A.

    2011-01-01

    Introduction: The growing numbers of cancer survivors will challenge the ability of oncologists to provide ongoing surveillance care. Tools such as survivorship care plans (SCPs) are needed to effectively care for these patients. The UCLA-LIVESTRONG Survivorship Center of Excellence has been providing SCPs to cancer survivors and their providers since 2006. We sought to examine views on the value and impact of SCPs from a primary care provider (PCP) perspective. Methods: As part of a quality improvement project, we invited 32 PCPs who had received at least one SCP to participate in a semistructured interview focused on (1) the perceived value of SCPs for patient management and (2) PCP attitudes toward follow-up care for cancer survivors. Interviews were tape-recorded, transcribed, and analyzed. Results: Fifteen PCPs participated in the interviews and had received a total of 30 SCPs. Ten of them indicated reading the SCPs before being contacted for the interview. All 10 PCPs indicated that the SCP provided additional information about the patient's cancer history and/or recommendations for follow-up care, and eight reported a resulting change in patient care. PCPs identified useful elements of the SCP that assisted them with patient care, and they valued the comprehensive format of the SCP. PCPs indicated that after reading the SCPs they felt more confident and better prepared to care for the cancer survivor. Conclusion: SCPs were highly valued by these PCPs, increasing their knowledge about survivors' cancer history and recommended surveillance care and influencing patient care. PMID:22211129

  15. Co-Planning among Science and Special Education Teachers: How Do Different Conceptual Lenses Help to Make Sense of the Process?

    ERIC Educational Resources Information Center

    Swanson, Lauren H.; Bianchini, Julie A.

    2015-01-01

    In this study, we investigated the process of teacher co-planning. We examined two teams of high school science and special education teachers brought together to co-plan inclusive, inquiry-oriented science units as part of a professional development effort. We used three conceptual lenses to help make sense of this process: (1) characteristics of…

  16. Are Discussions about College between Parents and Their High School Children a College-Planning Activity? Making the Case and Testing the Predictors

    ERIC Educational Resources Information Center

    Myers, Scott M.; Myers, Carrie B.

    2012-01-01

    Our research goals are to make the case that parent-student discussions about college planning should be seen as a distinct college-planning activity and to identify and test the relevant predictors of these discussions. Findings from over 4,000 parents and their high school children show that parent-student discussions are enhanced when both the…

  17. Climate Resiliency Planning: Making Extreme Event Science Useful for Managers and Planners in Northern Nevada

    NASA Astrophysics Data System (ADS)

    McCarthy, M.; Kenneston, A.; Wall, T. U.; Brown, T. J.; Redmond, K. T.

    2014-12-01

    Effective climate resiliency planning at the regional level requires extensive interactive dialogue among climate scientists, emergency managers, public health officials, urban planners, social scientists, and policy makers. Engaging federal, tribal, state, local governments and private sector business and infrastructure owners/operators in defining, assessing and characterizing the impacts of extreme events allows communities to understand how different events "break the system" forcing local communities to seek support and resources from state/federal governments and/or the private sector and what actions can be taken proactively to mitigate consequences and accelerate recovery. The Washoe County Regional Resiliency Study was prepared in response to potential climate variability related impacts specific to the Northern Nevada Region. The last several decades have seen dramatic growth in the region, coupled with increased resource demands that have forced local governments to consider how those impacts will affect the region and may, in turn, impact the region's ability to provide essential services. The Western Regional Climate Center of the Desert Research Institute provided a synthesis of climate studies with predictions regarding plausible changes in the local climate of Northern California and Nevada for the next 50 years. In general, these predictions indicate that the region's climate is undergoing a gradual shift, which will primarily affect the frequency, amount, and form of precipitation in the Sierra Nevada and Great Basin. Changes in water availability and other extreme events may have serious and long lasting effects in the Northern Nevada Region, and create a variety of social, environmental and economic concerns. A range of extreme events were considered including Adverse Air Quality, Droughts, Floods, Heat Waves, High Wind, Structure Fires, Wildland Fires, and Major Winter Storms. Due to the complexity of our climate systems, and the difficulty in

  18. Development of a district information system for water management planning and strategic decision making

    NASA Astrophysics Data System (ADS)

    Loukas, A.; Tzabiras, J.; Spiliotopoulos, M.; Kokkinos, K.; Fafoutis, C.; Mylopoulos, N.

    2015-06-01

    The overall objective of this work is the development of a District Information System (DIS) which could be used by stakeholders for the purposes of a district day-to-day water management as well as for planning and strategic decisionmaking. The DIS was developed from a GIS-based modeling approach, which integrates a generic crop model and a hydraulic model of the transport/distribution system, using land use maps generated by Landsat TM imagery. The main sub-objectives are: (i) the development of an operational algorithm to retrieve crop evapotranspiration from remote sensing data, (ii) the development of an information system with friendly user interface for the data base, the crop module and the hydraulic module and (iii) the analysis and validation of management scenarios from model simulations predicting the respective behavior. The Lake Karla watershed is used in this study, but the overall methodology could be used as a basis for future analysis elsewhere. Surface Energy Balance Algorithm for Land (SEBAL) was used to derive monthly actual evapotranspiration (ET) values from Landsat TM imagery. Meteorological data from the archives of the Institute for Research and Technology, Thessaly (I.RE.TE.TH) has also been used. The methodology was developed using high quality Landsat TM images during 2007 growing season. Monthly ET values are used as an input to CROPWAT model. Outputs of CROPWAT model are then used as input for WEAP model. The developed scenario is based on the actual situation of the surface irrigation network of the Local Administration of Land Reclamation (LALR) of Pinios for the year of 2007. The DIS is calibrated with observed data of this year and the district parameterization is conducted based on the actual operation of the network. The operation of the surface irrigation network of Pinios LALR is simulated using Technologismiki Works, while the operation of closed pipe irrigation network of Lake Karla LALR is simulated using Watercad. Four

  19. Stage of Change for Making an Informed Decision about Medicare Health Plans

    PubMed Central

    Levesque, Deborah A; Cummins, Carol O; Prochaska, Janice M; Prochaska, James O

    2006-01-01

    Objective To assess the applicability of the transtheoretical model of change (TTM) to informed choice in the Medicare population. Data Sources/Study Setting Two hundred and thirty-nine new Medicare enrollees randomly selected from the Center for Medicare and Medicaid Services' October 2001 Initial Enrollee File, a repository of data for persons who are going to turn 65 and become entitled to enroll in Medicare in the next 3 months. Study Design Study participants completed TTM measures of stage of change, decisional balance, and self-efficacy for informed choice, as well as measures of Medicare knowledge, perceived knowledge, and information seeking. Model testing was conducted to determine whether well-established relationships between stage of change, decisional balance, and self-efficacy replicate for informed choice in the Medicare population, and whether Medicare knowledge and information-seeking increase across the stages. Data Collection/Extraction Methods Survey data were collected using mail surveys with telephone follow-up for nonresponders. Principal Findings Predicted relationships were established between stage of change for informed choice and decisional balance, self-efficacy, Medicare knowledge, and information seeking. The amount of variance accounted for by stage of change for informed choice was larger than that found for smoking cessation, where the TTM has had its greatest successes. Conclusions The methods and findings lay the groundwork for development of TTM-based interventions for Medicare beneficiaries, and provide a prototype for the application of the TTM to informed decision making among other types of consumers who are being asked to take more responsibility for their health care. PMID:16899013

  20. Compatibility study of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials.

    PubMed

    Yan, Qi-Long; Xiao-Jiang, Li; La-Ying, Zhang; Ji-Zhen, Li; Hong-Li, Li; Zi-Ru, Liu

    2008-12-30

    The compatibility of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials of solid propellants was studied by using the pressure DSC method where, cyclotetramethylenetetranitroamine (HMX), cyclotrimethylenetrinitramine (RDX), 1,4-dinitropiperazine (DNP), 1.25/1-NC/NG mixture, lead 3-nitro-1,2,4-triazol-5-onate (NTO-Pb), aluminum powder (Al, particle size=13.6microm) and N-nitrodihydroxyethylaminedinitrate (DINA) were used as energetic components and polyethylene glycol (PEG), polyoxytetramethylene-co-oxyethylene (PET), addition product of hexamethylene diisocyanate and water (N-100), 2-nitrodianiline (2-NDPA), 1,3-dimethyl-1,3-diphenyl urea (C2), carbon black (C.B.), aluminum oxide (Al2O3), cupric 2,4-dihydroxy-benzoate (beta-Cu), cupric adipate (AD-Cu) and lead phthalate (phi-Pb) were used as inert materials. It was concluded that the binary systems of TNAD with NTO-Pb, RDX, PET and Al powder are compatible, and systems of TNAD with DINA and HMX are slightly sensitive, and with 2-NDPA, phi-Pb, beta-Cu, AD-Cu and Al2O3 are sensitive, and with PEG, N-100, C2 and C.B. are incompatible. The impact and friction sensitivity data of the TNAD and TNAD in combination with the other energetic materials under present study was also obtained, and there was no consequential affiliation between sensitivity and compatibility.

  1. LDEF polymeric materials: 10 months versus 5.8 years of exposure

    NASA Technical Reports Server (NTRS)

    Young, Philip R.; Slemp, Wayne S.; Chang, Alice C.

    1993-01-01

    The chemical characterization of several polymeric materials which received 10 months of exposure and 5.8 years of exposure on a Row 9 Long Duration Exposure Facility (LDEF) experiment (A0134) is reported. Specimens include fluorinated ethylene propylene (FEP) teflon film, polysulfone film, and graphite fiber reinforced epoxy amd polysulfone matrix composites. The responses of these materials to the two LEO exposures are compared. The results of infrared, thermal, x-ray photoelectron, and scanning electron microscope analyses are reported. Solution property measurements of various molecular weight parameters are presented for the thermoplastic polysulfone materials. Molecular level effects attributable to exposure that were present in 10-month exposed specimens were not found in 5.8-year exposed specimens. This result suggests that increased atomic oxygen fluence toward the end of the LDEF mission may have eroded away selected environmentally induced changes in surface chemistry for 5.8-year exposure specimens.

  2. Antiloosening ability of 5/8 inch stainless steel BSW threaded fasteners

    NASA Astrophysics Data System (ADS)

    Panja, Bikash; Das, Santanu

    2016-07-01

    Threaded fasteners are popular for temporary joining of different components due to the fact that they retain high clamping force and torque for long. However, they may loosen under vibrating conditions causing failure of the system. In this experimental work, antiloosening ability of various 5/8 inch BSW fastening elements, such as conventional nut and nylock nut with flat washer, spring washer, inside and outside serrated washers is tested with stainless steel (SS) bolts. A hybrid double nut using a simple nut and one nylock nut at the outside and a typical adhesive bonded nut with 5/8 inch BSW bolt are introduced to obtain resistance to loosening. Some hybrid double nut and adhesive bonded nut are recommended for stainless steel 5/8 inch BSW bolts under vibration.

  3. 5. 8 GHz ophthalmic microwave applicator for treatment of choroidal melanoma

    SciTech Connect

    Finger, P.T.; Packer, S.; Svitra, P.; Paglione, R.W.; Albert, D.M.; Chess, J.

    1983-01-01

    We report on the use of a 5.8 GHz microwave applicator to treat choroidal melanoma (Greene) in rabbits. The physical requirements needed to treat these intraocular tumors are quite different from those encountered elsewhere in the body. From a trans-scleral approach the penetration needed is minimal (5 to 10 mm.). The fibrous sclera is the only structure between the heat source and the tumor. The sclera has a relatively low water content when compared to tumor. This fact in addition to the frequency dependent interactions of tissue and electromagnetic radiation, results in an advantage to the use of the 5.8 GHz microwave device in treating intraocular malignancies.

  4. The design and evaluation of a 5.8 ghz laptop-based radar system

    NASA Astrophysics Data System (ADS)

    Teng, Kevin Chi-Ming

    This project involves design and analysis of a 5.8 GHz laptop-based radar system. The radar system measures Doppler, ranging and forming Synthetic Aperture Radar (SAR) images utilizing Matlab software provided from MIT Open Courseware and performs data acquisition and signal processing. The main purpose of this work is to bring new perspective to the existing radar project by increasing the ISM band frequency from 2.4 GHz to 5.8 GHz and to carry out a series of experiments on the implementation of the radar kit. Demonstrating the radar at higher operating frequency is capable of providing accurate data results in Doppler, ranging and SAR images.

  5. Strategic planning for and implementation of reclaimed municipal waste water as make-up to a refinery cooling system

    SciTech Connect

    Francis, W.R.; Mazur, J.J.; Rao, N.M.

    1996-08-01

    This paper discusses the successful use of treated municipal plant waste water effluent (Title 22) in a refinery cooling water system. Conversion from well water to this make-up water source was preceded by developing a carefully crafted transition plan. Steps were taken to identify key system performance indicators, establish desired performance goals, and implement stringent monitoring and control protocols. In addition, all possible contingencies were considered and solutions developed. Treating Title 22 waters is very challenging and entails risks not associated with normal makeup waters. Several novel on-line monitoring and control tools are available which help minimize these risks while enhancing tower operation. Performance monitoring of critical system parameters is essential in order to provide early warning of problems so that corrective measures can be implemented. In addition, a high level of system automation enhances reliable operation. Corrosion, scaling and microbiological performance of the system with Title 22 water is discussed in comparison to previous well water make-up.

  6. RRP5 is required for formation of both 18S and 5.8S rRNA in yeast.

    PubMed Central

    Venema, J; Tollervey, D

    1996-01-01

    Three of the four eukaryotic ribosomal RNA molecules (18S, 5.8S and 25-28S) are synthesized as a single precursor which is subsequently processed into the mature rRNAs by a complex series of cleavage and modification reactions. In the yeast Saccharomyces cerevisiae, the early pre-rRNA cleavages at sites A0, A1 and A2, required for the synthesis of 18S rRNA, are inhibited in strains lacking RNA or protein components of the U3, U14, snR10 and snR30 small nucleolar ribonucleoproteins (snoRNPs). The subsequent cleavage at site A3, required for formation of the major, short form of 5.8S rRNA, is carried out by another ribonucleoprotein, RNase MRP. A screen for mutations showing synthetic lethality with deletion of the non-essential snoRNA, snR10, identified a novel gene, RRP5, which is essential for viability and encodes a 193 kDa nucleolar protein. Genetic depletion of Rrp5p inhibits the synthesis of 18S rRNA and, unexpectedly, also of the major short form of 5.8S rRNA. Pre-rRNA processing is concomitantly impaired at sites A0, A1, A2 and A3. This distinctive phenotype makes Rrp5p the first cellular component simultaneously required for the snoRNP-dependent cleavage at sites A0, A1 and A2 and the RNase MRP-dependent cleavage at A3 and provides evidence for a close interconnection between these processing events. Putative RRP5 homologues from Caenorhabditis elegans and humans were also identified, suggesting that the critical function of Rrp5p is evolutionarily conserved. Images PMID:8896463

  7. Into Adolescence: Actions for Wellpower. A Curriculum for Grades 5-8. Contemporary Health Series.

    ERIC Educational Resources Information Center

    Waters, Mae; Hocker, Anita

    This module on wellness includes eight lessons, and is oriented toward middle school students in grades 5-8. Students choose partners to support them in achieving their goals for improving health in several areas. In lesson 1, health and wellness are defined. Students are introduced to a wellness continuum and the physical, mental/emotional, and…

  8. The Columbia River: Its Future and You. Teacher's Manual for Grades 5-8.

    ERIC Educational Resources Information Center

    Frost, Marcia

    Designed as a part of a multidisciplinary set of curricula and educational materials on the Columbia River, this teacher's guide focuses on the many uses of the river and the conflicts arising from those uses. This unit's major purpose is to help students in grades 5-8 to start thinking about how the resources of the Columbia River should be…

  9. Diffusion of cis-5,8,11,14,17-eicosapentaenoic acid (1); carbon dioxide (2)

    NASA Astrophysics Data System (ADS)

    Winkelmann, J.

    This document is part of Subvolume A `Gases in Gases, Liquids and their Mixtures' of Volume 15 `Diffusion in Gases, Liquids and Electrolytes' of Landolt-Börnstein Group IV `Physical Chemistry'. It is part of the chapter of the chapter `Diffusion in Pure Gases' and contains data on diffusion of (1) cis-5,8,11,14,17-eicosapentaenoic acid; (2) carbon dioxide

  10. Earth Science Supplement to the Syllabus, Part 2, Topics 5-8, 1970 Edition. 1974 Reprint.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Secondary Curriculum Development.

    This document contains investigation topics 5-8 in the earth science course developed by the University of the State of New York for secondary schools. Topics include energy in earth processes, insulation and the earth's surface, energy exchanges in the atmosphere, moisture and energy budgets, and environmental change. Each topic is preceded by…

  11. Making a Quit Plan

    MedlinePlus

    ... activity to calendar Google Calendar iCal Outlook × 1 week smokefree Being smokefree for a week is a ... to calendar Google Calendar iCal Outlook × First Two Weeks What to expect: Most withdrawal symptoms will fade ...

  12. Multi-Agent Many-Objective Robust Decision Making: Supporting Cooperative Regional Water Portfolio Planning in the Eastern United States

    NASA Astrophysics Data System (ADS)

    Herman, J. D.; Zeff, H. B.; Reed, P. M.; Characklis, G. W.

    2013-12-01

    In the Eastern United States, water infrastructure and institutional frameworks have evolved in a historically water-rich environment. However, large regional droughts over the past decade combined with continuing population growth have marked a transition to a state of water scarcity, for which current planning paradigms are ill-suited. Significant opportunities exist to improve the efficiency of water infrastructure via regional coordination, namely, regional 'portfolios' of water-related assets such as reservoirs, conveyance, conservation measures, and transfer agreements. Regional coordination offers the potential to improve reliability, cost, and environmental impact in the expected future state of the world, and, with informed planning, to improve robustness to future uncertainty. In support of this challenge, this study advances a multi-agent many-objective robust decision making (multi-agent MORDM) framework that blends novel computational search and uncertainty analysis tools to discover flexible, robust regional portfolios. Our multi-agent MORDM framework is demonstrated for four water utilities in the Research Triangle region of North Carolina, USA. The utilities supply nearly two million customers and have the ability to interact with one another via transfer agreements and shared infrastructure. We show that strategies for this region which are Pareto-optimal in the expected future state of the world remain vulnerable to performance degradation under alternative scenarios of deeply uncertain hydrologic and economic factors. We then apply the Patient Rule Induction Method (PRIM) to identify which of these uncertain factors drives the individual and collective vulnerabilities for the four cooperating utilities. Our results indicate that clear multi-agent tradeoffs emerge for attaining robustness across the utilities. Furthermore, the key factor identified for improving the robustness of the region's water supply is cooperative demand reduction. This type

  13. Absorption features in the 5-8 micron spectra of protostars

    NASA Technical Reports Server (NTRS)

    Tielens, A. G. G. M.; Allamandola, L. J.; Bregman, J.; Goebel, J.; Witteborn, F. C.; Dhendecourt, L. B.

    1984-01-01

    High signal-to-noise ratio spectra in the range of 5-8 microns of four sources embedded in molecular clouds are examined using low-temperature laboratory measurements of the 5-8-micron spectra of simple molecules and their mixtures. The absorption, apparent in all four sources, is characterized by highly distinct features ranging from two relatively narrow bands at 6.0 and 6.8 microns in W33A to a broad, shallow, and partially structured feature extending from 5.2 to 7.8 microns in Mon R2-IRS2, BN, and NGC2264. The first feature (W33A) is explained by the OH bending mode in H2O and the CH deformation modes in saturated hydrocarbons; while the second feature (Mon R2-IRS2-type) is explained by the presence of a mixture of saturated and unsaturated hydrocarbons possibly containing strongly electronegative groups.

  14. Role of the community matron in advance care planning and 'do not attempt CPR' decision-making: a qualitative study.

    PubMed

    Kazmierski, Mandy; King, Nigel

    2015-01-01

    The community matron (CM) is often the key worker caring for patients with chronic, life-limiting, long-term conditions, but these patients are not always recognised as palliative cases. This study explored the experiences of CMs with regard to advance care planning (ACP) and 'do not attempt cardiopulmonary resuscitation' (DNACPR) decision-making to understand whether or not they felt adequately prepared for this aspect of their role, and why. Qualitative data were generated from six CMs using a broad interpretive phenomenological approach. Face-to-face recorded interviews were analysed using template analysis. The study found that although participants faced complex ethical situations around ACP and DNACPR almost on a daily basis, none had received any formal training despite the emphasis on training in national and local guidelines. Participants often struggled to get their patients accepted on to the Gold Standards Framework. The research found variability and complexity of cases to be the main barriers to clear identification of the palliative phase.

  15. A 5.8S nuclear ribosomal RNA gene sequence database: applications to ecology and evolution

    NASA Technical Reports Server (NTRS)

    Cullings, K. W.; Vogler, D. R.

    1998-01-01

    We complied a 5.8S nuclear ribosomal gene sequence database for animals, plants, and fungi using both newly generated and GenBank sequences. We demonstrate the utility of this database as an internal check to determine whether the target organism and not a contaminant has been sequenced, as a diagnostic tool for ecologists and evolutionary biologists to determine the placement of asexual fungi within larger taxonomic groups, and as a tool to help identify fungi that form ectomycorrhizae.

  16. Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity

    PubMed Central

    Suzuki, Takayuki; Hasso, Sean M.; Fallon, John F.

    2008-01-01

    The zone of polarizing activity is the primary signaling center controlling anterior–posterior patterning of the amniote limb bud. The autopodial interdigits (IDs) are secondary signaling centers proposed to determine digit identity by acting on the cells of the digital ray. Here, we focus on events accompanying digital fate determination and define a region of the digital ray that expresses Sox9 and Bmpr1b and is phosphorylated-SMAD1/5/8 (p-SMAD1/5/8) positive. We name this region the phalanx-forming region (PFR), and show that the PFR cells arise from the distal subridge mesenchyme of digital ray. This phalanx-forming cell lineage is subsequently committed to the cartilage lineage; the fate of these cells is initially labile but becomes fixed as they are incorporated into the condensed cartilage of the digit primordium. Using an in vivo reporter assay, we establish that each digital PFR has a unique p-SMAD1/5/8 activity signature. In addition, we show that changes in this activity correlate with the identity of the digit that forms after experimental manipulation, supporting the idea that threshold signaling levels can lead to different developmental outcomes in a morphogenetic field. Our data define the molecular profile of the PFR, and we propose a model for understanding formation and variation of digits during autopodial development. PMID:18334652

  17. 21 CFR 822.21 - What must I do if I want to make changes to my postmarket surveillance plan after you have...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false What must I do if I want to make changes to my postmarket surveillance plan after you have approved it? 822.21 Section 822.21 Food and Drugs FOOD AND DRUG... Review and Action § 822.21 What must I do if I want to make changes to my postmarket surveillance...

  18. 21 CFR 822.21 - What must I do if I want to make changes to my postmarket surveillance plan after you have...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false What must I do if I want to make changes to my postmarket surveillance plan after you have approved it? 822.21 Section 822.21 Food and Drugs FOOD AND DRUG... Review and Action § 822.21 What must I do if I want to make changes to my postmarket surveillance...

  19. 21 CFR 822.21 - What must I do if I want to make changes to my postmarket surveillance plan after you have...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false What must I do if I want to make changes to my postmarket surveillance plan after you have approved it? 822.21 Section 822.21 Food and Drugs FOOD AND DRUG... Review and Action § 822.21 What must I do if I want to make changes to my postmarket surveillance...

  20. 21 CFR 822.21 - What must I do if I want to make changes to my postmarket surveillance plan after you have...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false What must I do if I want to make changes to my postmarket surveillance plan after you have approved it? 822.21 Section 822.21 Food and Drugs FOOD AND DRUG... Review and Action § 822.21 What must I do if I want to make changes to my postmarket surveillance...

  1. 21 CFR 822.21 - What must I do if I want to make changes to my postmarket surveillance plan after you have...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false What must I do if I want to make changes to my postmarket surveillance plan after you have approved it? 822.21 Section 822.21 Food and Drugs FOOD AND DRUG... Review and Action § 822.21 What must I do if I want to make changes to my postmarket surveillance...

  2. 20 CFR 1002.262 - When is the employer required to make the plan contribution that is attributable to the employee...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... days after the date of reemployment, or when plan contributions are normally due for the year in which... allowed (but not required) to make up his or her missed contributions or elective deferrals. These makeup contributions or elective deferrals must be made during a time period starting with the date of reemployment...

  3. Co-planning among science and special education teachers: How do different conceptual lenses help to make sense of the process?

    NASA Astrophysics Data System (ADS)

    Swanson, Lauren H.; Bianchini, Julie A.

    2015-12-01

    In this study, we investigated the process of teacher co-planning. We examined two teams of high school science and special education teachers brought together to co-plan inclusive, inquiry-oriented science units as part of a professional development effort. We used three conceptual lenses to help make sense of this process: (1) characteristics of collaboration, (2) small group interactions, and (3) community discourse. Using these lenses individually and collectively, we identified strengths and limitations in teachers' co-planning efforts. A strength was that all teachers, irrespective of discipline, shared ideas and helped make decisions about the content and activities included in unit and lesson plans. A limitation was that teachers, again irrespective of discipline, discussed science education topics in their teams more often than special education ones. We found this latter finding of note as it spoke to issues of parity among teachers during the professional development. In our discussion, we argue that each conceptual lens yielded both unique and common findings on co-planning. We also provide recommendations for professional developers and educational scholars intent on organizing and/or researching co-planning among science and special education teachers.

  4. Taming Data to Make Decisions: Using a Spatial Fuzzy Logic Decision Support Framework to Inform Conservation and Land Use Planning

    NASA Astrophysics Data System (ADS)

    Sheehan, T.; Baker, B.; Degagne, R. S.

    2015-12-01

    With the abundance of data sources, analytical methods, and computer models, land managers are faced with the overwhelming task of making sense of a profusion of data of wildly different types. Luckily, fuzzy logic provides a method to work with different types of data using language-based propositions such as "the landscape is undisturbed," and a simple set of logic constructs. Just as many surveys allow different levels of agreement with a proposition, fuzzy logic allows values reflecting different levels of truth for a proposition. Truth levels fall within a continuum ranging from Fully True to Fully False. Hence a fuzzy logic model produces continuous results. The Environmental Evaluation Modeling System (EEMS) is a platform-independent, tree-based, fuzzy logic modeling framework. An EEMS model provides a transparent definition of an evaluation model and is commonly developed as a collaborative effort among managers, scientists, and GIS experts. Managers specify a set of evaluative propositions used to characterize the landscape. Scientists, working with managers, formulate functions that convert raw data values into truth values for the propositions and produce a logic tree to combine results into a single metric used to guide decisions. Managers, scientists, and GIS experts then work together to implement and iteratively tune the logic model and produce final results. We present examples of two successful EEMS projects that provided managers with map-based results suitable for guiding decisions: sensitivity and climate change exposure in Utah and the Colorado Plateau modeled for the Bureau of Land Management; and terrestrial ecological intactness in the Mojave and Sonoran region of southern California modeled for the Desert Renewable Energy Conservation Plan.

  5. Measurement of sputtered efflux from 5-, 8-, and 30-cm diameter mercury ion thrusters

    NASA Technical Reports Server (NTRS)

    Weigand, A. J.; Mirtich, M. J.

    1975-01-01

    A study was undertaken to investigate the sputtered efflux from 5-, 8-, and 30-cm diameter mercury ion thrusters. Quartz crystal microbalances and fused silica samples were used to analyze the sputtered flux. Spectral transmittance measurements and spectrographic analysis of the samples were made after they were exposed to different thruster effluence by operating the thrusters at various conditions and durations of time. These measurements were used to locate the source of the efflux and determine its accumulated effect at various locations near the thruster. Comparisons of in situ and ex situ transmittance measurements of samples exposed to thruster efflux are also presented.

  6. BMP4 Enhances Foam Cell Formation by BMPR-2/Smad1/5/8 Signaling

    PubMed Central

    Feng, Jun; Gao, Jiangfei; Li, Yuxin; Yang, Yanhua; Dang, Lili; Ye, Yuanpeng; Deng, Jingyuan; Li, Antai

    2014-01-01

    Atherosclerosis and its complications are characterized by lipid-laden foam cell formation. Recently, an obvious up-regulation of BMP4 was observed in atherosclerotic plaque, however, its function and the underlying mechanism remains unknown. In our study, BMP4 pretreatment induced macrophage foam cell formation. Furthermore, a dramatic increase in the ratio of cholesteryl ester (CE) to total cholesterol (TC) was observed in BMP4-treated macrophages, accompanied by the reduction of cholesterol outflow. Importantly, BMP4 stimulation inhibited the expression levels of the two most important cellular cholesterol transporters ABCA1 and ABCG1, indicating that BMP4 may induce formation of foam cells by attenuating transporters expression. Further mechanism analysis showed that BMPR-2, one of the BMP4 receptors, was significantly increased in BMP4 treated macrophage foam cells. That blocking its expression using specific siRNA significantly increased ABCA1 and ABCG1 levels. Additionally, BMP4 treatment triggered the activation of Smad1/5/8 pathway by BMPR-2 signaling. After blocking the Smad1/5/8 with its inhibitor, ABCA1 and ABCG1 expression levels were up-regulated significantly, suggesting that BMP4 inhibited the expression of ABCA1 and ABCG1 through the BMPR-2/Smad1/2/8 signaling pathway. Therefore, our results will provide a new insight about how BMP4 accelerate the progressio of atherosclerosis, and it may become a potential target against atherosclerosis and its complications. PMID:24690996

  7. 5 S and 5.8 S ribosomal RNA sequences and protist phylogenetics.

    PubMed

    Walker, W F

    1985-01-01

    More than 100 5 S 5.8 S rRNA sequences from protists, including fungi, are known. Through a combination of quantitative treeing and special consideration of "signature' nucleotide combinations, the most significant phylogenetic implications of these data are emphasized. Also, limitations of the data for phylogenetic inferences are discussed and other significant data are brought to bear on the inferences obtained. 5 S sequences from red algae are seen as the most isolated among eukaryotics. A 5 S sequence lineage consisting of oomycetes, euglenoids, most protozoa, most slime molds and perhaps dinoflagellates and mesozoa is defined. Such a lineage is not evident from 5.8 S rRNA or cytochrome c sequence data. 5 S sequences from Ascomycota and Basidiomycota are consistent with the proposal that each is derived from a mycelial form with a haploid yeast phase and simple septal pores, probably most resembling present Taphrinales. 5 S sequences from Chytridiomycota and Zygomycota are not clearly distinct from each other and suggest that a major lineage radiation occurred in the early history of each. Qualitative biochemical data clearly supports a dichotomy between an Ascomycota-Basidiomycota lineage and a Zygomycota-Chytridiomycota lineage.

  8. Learning to Teach in a Context of Education Reform: Liberal Studies Student Teachers' Decision-Making in Lesson Planning

    ERIC Educational Resources Information Center

    Lai, Edith; Lam, Chi-Chung

    2011-01-01

    Liberal studies is a new subject in the new senior secondary curriculum in Hong Kong. This study attempted to identify factors that shape liberal studies student teachers' decisions in lesson planning. Based on interview data and lesson plans developed by the student teachers, this article maintains that four factors interacted with the subject…

  9. 40 CFR 60.1070 - How do I make my draft materials separation plan available to the public?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... available to the public? (a) Distribute your draft materials separation plan to the main public libraries in... location of the public libraries where the public can find your materials separation plan. Include the normal business hours of each library. (5) An agenda of the topics that will be discussed at the...

  10. Strategic Decision Making in Higher Education: An Analysis of the New Planning System in Dutch Higher Education.

    ERIC Educational Resources Information Center

    Maassen, Peter, A. M.; Potman, Henry P.

    1990-01-01

    The new strategic planning system in Dutch higher education is described and the usefulness of strategic planning in higher education institutions in general is discussed. Three models are distinguished: linear, adaptive, and interpretive. Evidence suggesting the system has resulted in more homogenization than diversification is presented.…

  11. Effects of Information Visualization on Older Adults’ Decision-Making Performance in a Medicare Plan Selection Task: A Comparative Usability Study

    PubMed Central

    Price, Margaux M; Crumley-Branyon, Jessica J; Leidheiser, William R

    2016-01-01

    Background Technology gains have improved tools for evaluating complex tasks by providing environmental supports (ES) that increase ease of use and improve performance outcomes through the use of information visualizations (info-vis). Complex info-vis emphasize the need to understand individual differences in abilities of target users, the key cognitive abilities needed to execute a decision task, and the graphical elements that can serve as the most effective ES. Older adults may be one such target user group that would benefit from increased ES to mitigate specific declines in cognitive abilities. For example, choosing a prescription drug plan is a necessary and complex task that can impact quality of life if the wrong choice is made. The decision to enroll in one plan over another can involve comparing over 15 plans across many categories. Within this context, the large amount of complex information and reduced working memory capacity puts older adults’ decision making at a disadvantage. An intentionally designed ES, such as an info-vis that reduces working memory demand, may assist older adults in making the most effective decision among many options. Objective The objective of this study is to examine whether the use of an info-vis can lower working memory demands and positively affect complex decision-making performance of older adults in the context of choosing a Medicare prescription drug plan. Methods Participants performed a computerized decision-making task in the context of finding the best health care plan. Data included quantitative decision-making performance indicators and surveys examining previous history with purchasing insurance. Participants used a colored info-vis ES or a table (no ES) to perform the decision task. Task difficulty was manipulated by increasing the number of selection criteria used to make an accurate decision. A repeated measures analysis was performed to examine differences between the two table designs. Results Twenty

  12. Nutrition education needs and learning preferences of Michigan students in grades 5, 8, and 11.

    PubMed

    Murphy, A S; Youatt, J P; Hoerr, S L; Sawyer, C A; Andrews, S L

    1994-09-01

    An assessment of nutrition education needs and learning preferences of students in grades 5, 8, and 11 was conducted to target instruction toward areas of highest need and strongest interest of students using teaching methods they prefer. This research evaluated students' knowledge, attitudes, and practices related to the Dietary Guidelines for Americans, including knowledge of the new Food Guide Pyramid; attitudes about school lunches and learning about nutrition; nutrition topics of interest; and preferred methods for learning about nutrition. Although results varied across grade level, generally students need to learn about the Food Guide Pyramid; the relationship between dietary fat, weight status, and health; and food sources of fat, salt, and fiber. They want to learn about personal health--how to control weight, improve diet, and prevent disease--using instructional methods that actively involve them. Results provide information relative to students' interest, understanding, and application of the Dietary Guidelines. PMID:7996832

  13. Photoacoustic microscopy with an enhanced axial resolution of 5.8 μm

    NASA Astrophysics Data System (ADS)

    Zhang, Chi; Zhou, Yong; Li, Chiye; Wang, Lihong V.

    2014-03-01

    The axial resolution of photoacoustic microscopy (PAM) can be enhanced by reducing the speed of sound within the imaging region of interest. This principle was demonstrated on a previously-reported PAM system, which utilized a 125 MHz ultrasonic transducer for signal detection and the Wiener deconvolution for signal processing. With sound slowed by silicone oil immersion, we have achieved a finest axial resolution of 5.8 μm for PAM, as validated by phantom experiments. The axial resolution was also enhanced in vivo when mouse ears injected with silicone oil were imaged. After injection of silicone oil, the blood vessels were resolved more clearly. When tissue-compatible low-speed liquids become available, this approach may find applications in PAM as well as in other imaging modalities, such as photoacoustic computed tomography and ultrasound imaging.

  14. Initial assessment of the intensity distribution of the 2011 Mw5.8 Mineral, Virginia, earthquake

    USGS Publications Warehouse

    Hough, Susan E.

    2012-01-01

    The intensity data collected by the U.S. Geological Survey (USGS) "Did You Feel It?" (DYFI) Website (USGS, DYFI; http://earthquake.usgs.gov/earthquakes/dyfi/events/se/082311a/us/index.html, last accessed Sept 2011) for the Mw5.8 Mineral, Virginia, earthquake, are unprecedented in their spatial richness and geographical extent. More than 133,000 responses were received during the first week following the earthquake. Although intensity data have traditionally been regarded as imprecise and generally suspect (e.g., Hough 2000), there is a growing appreciation for the potential utility of spatially rich, systematically determined DYFI data to address key questions in earthquake ground-motions science (Atkinson and Wald, 2007; Hauksson et al., 2008).

  15. Development of a 14-vane, double-strapped, 5.8-GHz magnetron oscillator

    NASA Astrophysics Data System (ADS)

    Choi, Jin Joo; Lee, Han Seoul; Jang, Kwang Ho; Sim, Sung Hun; Choi, Heung Sik

    2016-08-01

    Experiments on a 14-vane, double-strapped magnetron oscillator were performed to demonstrate high-power, high-efficiency coherent radiation at 5.8 GHz. The double-strapped magnetron was designed by using the Buneman-Hatree resonance condition, electromagnetic simulations and non-linear three-dimensional particle-in-cell (PIC) simulations. Experiments showed an oscillation output power of 5.3 kW at 5.79 GHz, corresponding to a DC-RF conversion efficiency of 57%. The cathode voltage was 9.2 kV, the collected anode current was 1 A, and the external magnetic field is 7.5 kG. Experimental results for the RF power, oscillation frequency, and efficiency were in good agreement with the corresponding values from non-linear three-dimensional PIC simulations.

  16. The influence of interdisciplinary collaboration on decision making: a framework to analyse stakeholder coalitions, evolution and learning in strategic delta planning

    NASA Astrophysics Data System (ADS)

    Vermoolen, Myrthe; Hermans, Leon

    2015-04-01

    The sustained development of urbanizing deltas requires that conflicting interests are reconciled, in an environment characterized by technical complexity and knowledge limitations. However, integrating ideas and establishing cooperation between actors with different backgrounds and roles still proves a challenge. Agreeing on strategic choices is difficult and implementation of agreed plans may lead to unanticipated and unintended outcomes. How can individual disciplinary perspectives come together and establish a broadly-supported and well-informed plan, the implementation of which contributes to sustainable delta development? The growing recognition of this need to bring together different stakeholders and different disciplinary perspectives runs parallel to a paradigm shift from 'hard' hydrological engineering to multi-functional and more 'soft' hydrological engineering in water management. As a result, there is now more attention for interdisciplinary collaboration that not only takes the physical characteristics of water systems into account, but also the interaction between physical and societal components of these systems. Thus, it is important to study interdisciplinary collaboration and how this influences decision-making. Our research looks into this connection, using a case in delta planning in the Netherlands, where there have been several (attempts for) integration of spatial planning and flood risk/ water management, e.g. in the case of the Dutch Delta Programme. This means that spatial designers and their designs play an important role in the strategic delta planning process as well, next to civil engineers, etc. This study explores the roles of stakeholders, experts and policy makers in interdisciplinary decision-making in dynamic delta planning processes, using theories and methods that focus on coalitions, learning and changes over time in policy and planning processes. This requires an expansion of the existing frameworks to study

  17. 31 CFR 5.8 - When will Treasury entities suspend or terminate debt collection on a Treasury debt?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... provisions of 31 CFR part 903 and the Treasury entity's policies and procedures. Legal counsel approval to terminate debt collection activity is required as described in Treasury Directive 34-02 (Credit Management... or terminate debt collection on a Treasury debt? 5.8 Section 5.8 Money and Finance: Treasury...

  18. 18 CFR 5.8 - Notice of commencement of proceeding and scoping document, or of approval to use traditional...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Notice of commencement... alternative procedures. 5.8 Section 5.8 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... thereunder at 50 CFR part 402, section 305(b) of the Magnuson-Stevens Fishery Conservation and Management...

  19. 18 CFR 5.8 - Notice of commencement of proceeding and scoping document, or of approval to use traditional...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Notice of commencement... alternative procedures. 5.8 Section 5.8 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE...

  20. 18 CFR 5.8 - Notice of commencement of proceeding and scoping document, or of approval to use traditional...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Notice of commencement... alternative procedures. 5.8 Section 5.8 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE...

  1. The ANSS response to the Mw 5.8 Central Virginia Seismic Zone earthquake of August 23, 2011

    NASA Astrophysics Data System (ADS)

    McNamara, D. E.; Horton, S.; Benz, H.; Earle, P. S.; Withers, M. M.; Hayes, G. P.; Kim, W. Y.; Chapman, M. C.; Herrmann, R. B.; Petersen, M. D.; Williams, R. A.

    2011-12-01

    An Mw 5.8 earthquake (depth=6km) occurred on August 23, 2011 (17:51:04 UTC) near Mineral, Virginia, which was widely felt from Maine to Georgia along the eastern seaboard and west to Chicago and western Tennessee. The USGS tallied nearly 142,000 felt reports submitted to the Did You Feel It (DYFI) internet community intensity system, making it the most widely felt earthquake since the web-site began, and demonstrating that more people felt this earthquake than any other in U.S. history. Significant damage was reported in the epicentral area and as far away as Washington D.C. (135 km away); minor damage was reported in Baltimore (200 km). The reverse faulting earthquake occurred on a northeast-striking plane within a region of diffuse seismicity known as the Central Virginia Seismic Zone. Within the first week, the mainshock was followed by 17 aftershocks with magnitude greater than 2, including Mw 4.5, 4.2, and 3.8 events. In the days following the mainshock, 46 portable seismic stations were deployed by several organizations, making this among the best-recorded aftershock sequence in the eastern U.S. Within 24 hours of the mainshock, 8 portable stations were deployed in time to record the largest aftershock to date (M4.5). We will present the results of our post-earthquake response, including attenuation and site amplification observations using portable aftershock station data, details on the initial USGS NEIC post earthquake response products and an assessment of the seismotectonics of the Central Virginia Seismic Zone based on aftershock locations and source parameter modeling of the larger earthquakes.

  2. Understanding the Voice of the Customer: Practical, Data-Driven Planning and Decision Making for Access Services

    ERIC Educational Resources Information Center

    Huff-Eibl, Robyn; Miller-Wells, John; Begay, Wendy

    2014-01-01

    This article describes the process and role frontline access and public service staff play in needs assessment and evaluation of user services, specifically in understanding the voice of the customer. Information includes how the University of Arizona Libraries have incorporated daily data collection into the strategic planning process, resources…

  3. Strategic Planning and Decision Making in Higher Education:What Gets Attention and What Doesn't

    ERIC Educational Resources Information Center

    Choban, Michael E.; Choban, Gary M.; Choban, David

    2008-01-01

    Why is the implementation of learning outcomes assessment in higher education proceeding so grudgingly? When assessment results are obtained, why are they so rarely integrated into the strategic planning process? These questions remain prominent in spite of over a decade of intensive effort on the part of educational accrediting agencies to…

  4. Making the Jump to Hybrid Space: Employing Face-to-Face and Online Modalities in a Special Event Planning Course

    ERIC Educational Resources Information Center

    Fortune, Mary F.

    2012-01-01

    Every quarter at California State University East Bay, a special event-planning course is offered in a hybrid format (face-to-face and online) and uses interactive Problem-Based Learning (PBL) activities designed to challenge and inspire intellectual growth. The PLB method is different in that students are not only receivers of knowledge but are…

  5. Planning and Decision Making about the Future Care of Older Group Home Residents and Transition to Residential Aged Care

    ERIC Educational Resources Information Center

    Bigby, C.; Bowers, B.; Webber, R.

    2011-01-01

    Background: Planning for future care after the death of parental caregivers and adapting disability support systems to achieve the best possible quality of life for people with intellectual disability as they age have been important issues for more than two decades. This study examined perceptions held by family members, group home staff and…

  6. Geotechnical aspects in the epicentral region of the 2011, Mw5.8 Mineral, Virginia earthquake

    USGS Publications Warehouse

    Green, Russell A.; Lasley, Samuel; Carter, Mark W.; Munsey, Jeffrey W.; Maurer, Brett W.; Tuttle, Martitia P.

    2015-01-01

    A reconnaissance team documented the geotechnical and geological aspects in the epicentral region of the Mw (moment magnitude) 5.8 Mineral, Virginia (USA), earthquake of 23 August 2011. Tectonically and seismically induced ground deformations, evidence of liquefaction, rock slides, river bank slumps, ground subsidence, performance of earthen dams, damage to public infrastructure and lifelines, and other effects of the earthquake were documented. This moderate earthquake provided the rare opportunity to collect data to help assess current geoengineering practices in the region, as well as to assess seismic performance of the aging infrastructure in the region. Ground failures included two marginal liquefaction sites, a river bank slump, four minor rockfalls, and a ~4-m-wide, ~12-m-long, ~0.3-m-deep subsidence on a residential property. Damage to lifelines included subsidence of the approaches for a bridge and a water main break to a heavily corroded, 5-cm-diameter valve in Mineral, Virginia. Observed damage to dams, landfills, and public-use properties included a small, shallow slide in the temporary (“working”) clay cap of the county landfill, damage to two earthen dams (one in the epicentral region and one further away near Bedford, Virginia), and substantial structural damage to two public school buildings.

  7. Smad1/5/8 are myogenic regulators of murine and human mesoangioblasts

    PubMed Central

    Costamagna, Domiziana; Quattrocelli, Mattia; van Tienen, Florence; Umans, Lieve; de Coo, Irineus F. M.; Zwijsen, An; Huylebroeck, Danny; Sampaolesi, Maurilio

    2016-01-01

    Mesoangioblasts (MABs) are vessel-associated stem cells that express pericyte marker genes and participate in skeletal muscle regeneration. Molecular circuits that regulate the myogenic commitment of MABs are still poorly characterized. The critical role of bone morphogenetic protein (BMP) signalling during proliferation and differentiation of adult myogenic precursors, such as satellite cells, has recently been established. We evaluated whether BMP signalling impacts on the myogenic potential of embryonic and adult MABs both in vitro and in vivo. Addition of BMP inhibited MAB myogenic differentiation, whereas interference with the interactions between BMPs and receptor complexes induced differentiation. Similarly, siRNA-mediated knockdown of Smad8 in Smad1/5-null MABs or inhibition of SMAD1/5/8 phosphorylation with Dorsomorphin (DM) also improved myogenic differentiation, demonstrating a novel role of SMAD8. Moreover, using a transgenic mouse model of Smad8 deletion, we demonstrated that the absence of SMAD8 protein improved MAB myogenic differentiation. Furthermore, once injected into α-Sarcoglycan (Sgca)-null muscles, DM-treated MABs were more efficacious to restore α-sarcoglycan (αSG) protein levels and re-establish functional muscle properties. Similarly, in acute muscle damage, DM-treated MABs displayed a better myogenic potential compared with BMP-treated and untreated cells. Finally, SMADs also control the myogenic commitment of human MABs (hMABs). BMP signalling antagonists are therefore novel candidates to improve the therapeutic effects of hMABs. PMID:26450990

  8. Smad1/5/8 are myogenic regulators of murine and human mesoangioblasts.

    PubMed

    Costamagna, Domiziana; Quattrocelli, Mattia; van Tienen, Florence; Umans, Lieve; de Coo, Irineus F M; Zwijsen, An; Huylebroeck, Danny; Sampaolesi, Maurilio

    2016-02-01

    Mesoangioblasts (MABs) are vessel-associated stem cells that express pericyte marker genes and participate in skeletal muscle regeneration. Molecular circuits that regulate the myogenic commitment of MABs are still poorly characterized. The critical role of bone morphogenetic protein (BMP) signalling during proliferation and differentiation of adult myogenic precursors, such as satellite cells, has recently been established. We evaluated whether BMP signalling impacts on the myogenic potential of embryonic and adult MABs both in vitro and in vivo. Addition of BMP inhibited MAB myogenic differentiation, whereas interference with the interactions between BMPs and receptor complexes induced differentiation. Similarly, siRNA-mediated knockdown of Smad8 in Smad1/5-null MABs or inhibition of SMAD1/5/8 phosphorylation with Dorsomorphin (DM) also improved myogenic differentiation, demonstrating a novel role of SMAD8. Moreover, using a transgenic mouse model of Smad8 deletion, we demonstrated that the absence of SMAD8 protein improved MAB myogenic differentiation. Furthermore, once injected into α-Sarcoglycan (Sgca)-null muscles, DM-treated MABs were more efficacious to restore α-sarcoglycan (αSG) protein levels and re-establish functional muscle properties. Similarly, in acute muscle damage, DM-treated MABs displayed a better myogenic potential compared with BMP-treated and untreated cells. Finally, SMADs also control the myogenic commitment of human MABs (hMABs). BMP signalling antagonists are therefore novel candidates to improve the therapeutic effects of hMABs. PMID:26450990

  9. Human platelets produce 14,15-oxido-5,8,11-eicosatrienoic acid from phosphatidylinositol

    SciTech Connect

    Ballou, L.R.; Lam, B.K.; Wong, P.Y.K.; Cheung, W.Y.

    1987-05-01

    Human platelets contain a soluble enzyme or enzyme system which catalyzes the formation of a compound more polar than arachidonate from 2-arachidonyl-sn-phosphatidylinositol (PtdIns). The C-value and mass spectrum of the compound appears similar to the reported values of 14,15-oxido-5,8,11-eicosatrienoic acid (EET). 2-Arachidonyl-sn-phosphatidylcholine, 2-arachidonyl-sn-phosphatidylethanolamine and arachidonic acid were not substrates for EET production. The reaction was Ca/sup 2 +/-dependent and insensitive to aspirin, mepacrin and indomethacin. EET formation was greatly reduced under nitrogen or carbon monoxide, however, exposure to atmospheric air rapidly restored EET production to a rate comparable to that under air. Further, neither NADPH nor cyanide affected EET formation, suggesting that a cytochrome P-450 system was not involved. Intact platelets prelabeled with (/sup 14/C)arachidonic acid generated at least 0.5 nmole of EET/10/sup 9/ platelets in response to thrombin; other agonists such as collagen, epinephrine, ADP or ionophore A23187 were not effective. Collectively, these data suggest that human platelets possess an enzyme system which appears to catalyze epoxidation of the arachidonyl moiety of PtdIns and its subsequent hydrolysis to yield EET.

  10. Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation.

    PubMed

    Lee, Sun Joo; Jeong, Ji Yun; Oh, Chang Joo; Park, Sungmi; Kim, Joon-Young; Kim, Han-Jong; Doo Kim, Nam; Choi, Young-Keun; Do, Ji-Yeon; Go, Younghoon; Ha, Chae-Myeong; Ha, Chae-Myung; Choi, Je-Yong; Huh, Seung; Ho Jeoung, Nam; Lee, Ki-Up; Choi, Hueng-Sik; Wang, Yu; Park, Keun-Gyu; Harris, Robert A; Lee, In-Kyu

    2015-01-01

    Vascular calcification, a pathologic response to defective calcium and phosphate homeostasis, is strongly associated with cardiovascular mortality and morbidity. In this study, we have observed that pyruvate dehydrogenase kinase 4 (PDK4) is upregulated and pyruvate dehydrogenase complex phosphorylation is increased in calcifying vascular smooth muscle cells (VSMCs) and in calcified vessels of patients with atherosclerosis, suggesting that PDK4 plays an important role in vascular calcification. Both genetic and pharmacological inhibition of PDK4 ameliorated the calcification in phosphate-treated VSMCs and aortic rings and in vitamin D3-treated mice. PDK4 augmented the osteogenic differentiation of VSMCs by phosphorylating SMAD1/5/8 via direct interaction, which enhances BMP2 signaling. Furthermore, increased expression of PDK4 in phosphate-treated VSMCs induced mitochondrial dysfunction followed by apoptosis. Taken together, our results show that upregulation of PDK4 promotes vascular calcification by increasing osteogenic markers with no adverse effect on bone formation, demonstrating that PDK4 is a therapeutic target for vascular calcification. PMID:26560812

  11. Into Adolescence: Living in a Family. A Curriculum for Grades 5-8. Contemporary Health Series.

    ERIC Educational Resources Information Center

    Post, Jory

    This module teaches respect for diversity in family structures, cultural values, and tradition. It gives middle school teachers 11 lessons and teaching plans that are sensitive to the wide range of family experiences of their students. The book emphasizes the importance of providing for the basic needs of family members--shelter and food,…

  12. Neurocognitive enhancement or impairment? A systematic meta-analysis of prescription stimulant effects on processing speed, decision-making, planning, and cognitive perseveration.

    PubMed

    Marraccini, Marisa E; Weyandt, Lisa L; Rossi, Joseph S; Gudmundsdottir, Bergljot Gyda

    2016-08-01

    Increasing numbers of adults, particularly college students, are misusing prescription stimulants primarily for cognitive/academic enhancement, so it is critical to explore whether empirical findings support neurocognitive benefits of prescription stimulants. Previous meta-analytic studies have supported small benefits from prescription stimulants for the cognitive domains of inhibitory control and memory; however, no meta-analytic studies have examined the effects on processing speed or the potential impairment on other domains of cognition, including planning, decision-making, and cognitive perseveration. Therefore, the present study conducted a meta-analysis of the available literature examining the effects of prescription stimulants on specific measures of processing speed, planning, decision-making, and cognitive perseveration among healthy adult populations. The meta-analysis results indicated a positive influence of prescription stimulant medication on processing speed accuracy, with an overall mean effect size of g = 0.282 (95% CI [0.077, 0.488]; n = 345). Neither improvements nor impairments were revealed for planning time, planning accuracy, advantageous decision-making, or cognitive perseveration; however, findings are limited by the small number of studies examining these outcomes. Findings support that prescription stimulant medication may indeed act as a neurocognitive enhancer for accuracy measures of processing speed without impeding other areas of cognition. Considering that adults are already engaging in illegal use of prescription stimulants for academic enhancement, as well as the potential for stimulant misuse to have serious side effects, the establishment of public policies informed by interdisciplinary research surrounding this issue, whether restrictive or liberal, is of critical importance. (PsycINFO Database Record

  13. Neurocognitive enhancement or impairment? A systematic meta-analysis of prescription stimulant effects on processing speed, decision-making, planning, and cognitive perseveration.

    PubMed

    Marraccini, Marisa E; Weyandt, Lisa L; Rossi, Joseph S; Gudmundsdottir, Bergljot Gyda

    2016-08-01

    Increasing numbers of adults, particularly college students, are misusing prescription stimulants primarily for cognitive/academic enhancement, so it is critical to explore whether empirical findings support neurocognitive benefits of prescription stimulants. Previous meta-analytic studies have supported small benefits from prescription stimulants for the cognitive domains of inhibitory control and memory; however, no meta-analytic studies have examined the effects on processing speed or the potential impairment on other domains of cognition, including planning, decision-making, and cognitive perseveration. Therefore, the present study conducted a meta-analysis of the available literature examining the effects of prescription stimulants on specific measures of processing speed, planning, decision-making, and cognitive perseveration among healthy adult populations. The meta-analysis results indicated a positive influence of prescription stimulant medication on processing speed accuracy, with an overall mean effect size of g = 0.282 (95% CI [0.077, 0.488]; n = 345). Neither improvements nor impairments were revealed for planning time, planning accuracy, advantageous decision-making, or cognitive perseveration; however, findings are limited by the small number of studies examining these outcomes. Findings support that prescription stimulant medication may indeed act as a neurocognitive enhancer for accuracy measures of processing speed without impeding other areas of cognition. Considering that adults are already engaging in illegal use of prescription stimulants for academic enhancement, as well as the potential for stimulant misuse to have serious side effects, the establishment of public policies informed by interdisciplinary research surrounding this issue, whether restrictive or liberal, is of critical importance. (PsycINFO Database Record PMID:27454675

  14. Synthesis and biological evaluation of quinoxaline-5,8-diones that inhibit vascular smooth muscle cell proliferation.

    PubMed

    Chung, Hwa-Jin; Jung, Ok-Jai; Chae, Mi Jin; Hong, Sung-Yu; Chung, Kwang-Hoe; Lee, Sang Kook; Ryu, Chung-Kyu

    2005-07-15

    A series of 6-arylamino-2,3-bis(pyridin-2-yl)-7-chloro-quinoxaline-5,8-diones were synthesized and evaluated for their inhibitory activity on the rat aortic smooth muscle cell (RAoSMC) proliferation. The quinoxaline-5,8-diones exhibited a potent antiproliferative activity. Further mechanistic study revealed that the inhibitory effect of one representative quinoxaline-5,8-dione on SMC proliferation was mediated by modulation of the extracellular signal-regulated kinase 1/2 signaling pathway in the RAoSMCs.

  15. Identification by affinity chromatography of the eukaryotic ribosomal proteins that bind to 5.8 S ribosomal ribonucleic acid.

    PubMed

    Ulbrich, N; Lin, A; Wool, I G

    1979-09-10

    The proteins that bind to rat liver 5.8 S ribosomal ribonucleic acid were identified by affinity chromatography. The nucleic acid was oxidized with periodate and coupled by its 3'-terminus to Sepharose 4B through and adipic acid dihydrazide spacer. The ribosomal proteins that associate with the immobilized 5.8 S rRNA were identified by polyacrylamide gel electrophoresiss: they were L19, L8, and L6 from the 60 S subunit; and S13 and S9 from the small subparticle. Small amounts of L14, L17', L18, L27/L27', and L35', and of S11, S15, S23/S24, and S26 also were bound to the affinity column, but whether they associate directly and specifically with 5.8 S rRNA is not known. Escherichia coli ribosomal proteins did not bind to the rat liver 5.8 S rRNA affinity column. PMID:468846

  16. Neglecting the Importance of the Decision Making and Care Regimes of Personal Support Workers: A Critique of Standardization of Care Planning Through the RAI/MDS

    PubMed Central

    Kontos, Pia C.; Miller, Karen-Lee; Mitchell, Gail J.

    2010-01-01

    Purpose: The Resident Assessment Instrument–Minimum Data Set (RAI/MDS) is an interdisciplinary standardized process that informs care plan development in nursing homes. This standardized process has failed to consistently result in individualized care planning, which may suggest problems with content and planning integrity. We examined the decision making and care practices of personal support workers (PSWs) in relation to the RAI/MDS standardized process. Design and Methods: This qualitative study utilized focus groups and semi-structured interviews with PSWs (n = 26) and supervisors (n = 9) in two nursing homes in central Canada. Results: PSWs evidenced unique occupational contributions to assessment via proximal familiarity and biographical information as well as to individualizing care by empathetically linking their own bodily experiences and forging bonds of fictive kinship with residents. These contributions were neither captured by RAI/MDS categories nor relayed to the interdisciplinary team. Causal factors for PSW exclusion included computerized records, low status, and poor interprofessional collaboration. Intraprofessional collaboration by PSWs aimed to compensate for exclusion and to individualize care. Implications: Exclusive institutional reliance on the RAI/MDS undermines quality care because it fails to capture residents’ preferences and excludes input by PSWs. Recommendations include incorporating PSW knowledge in care planning and documentation and examining PSWs’ nascent occupational identity and their role as interprofessional brokers in long-term care. PMID:20026525

  17. The Board of Trustees and the Making of Academic Policy. Planning for Higher Education; Vol. 3; No. 2; April 1974.

    ERIC Educational Resources Information Center

    Martin, Harold C.

    In order to play a proper role in the making of sound academic policy, the Board of Trustees must begin by taking itself seriously, and the first place for that is the choice of its members. It is essential that some members of the Board should be present or recent members of the professional academic community--teachers, research workers,…

  18. An Assessment of Decision-Making Processes: Evaluation of Where Land Protection Planning Can Incorporate Climate Change Information (Final Report)

    EPA Science Inventory

    This report, prepared by the Global Change Research Program (GCRP) in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA), is a review of decision-making processes of selected la...

  19. Incorporating ecosystem function concept in environmental planning and decision making by means of multi-criteria evaluation: the case-study of Kalloni, Lesbos, Greece.

    PubMed

    Oikonomou, Vera; Dimitrakopoulos, Panayiotis G; Troumbis, Andreas Y

    2011-01-01

    Nature provides life-support services which do not merely constitute the basis for ecosystem integrity but also benefit human societies. The importance of such multiple outputs is often ignored or underestimated in environmental planning and decision making. The economic valuation of ecosystem functions or services has been widely used to make these benefits economically visible and thus address this deficiency. Alternatively, the relative importance of the components of ecosystem value can be identified and compared by means of multi-criteria evaluation. Hereupon, this article proposes a conceptual framework that couples ecosystem function analysis, multi criteria evaluation and social research methodologies for introducing an ecosystem function-based planning and management approach. The framework consists of five steps providing the structure of a participative decision making process which is then tested and ratified, by applying the discrete multi-criteria method NAIADE, in the Kalloni Natura 2000 site, on Lesbos, Greece. Three scenarios were developed and evaluated with regard to their impacts on the different types of ecosystem functions and the social actors' value judgements. A conflict analysis permitted the better elaboration of the different views, outlining the coalitions formed in the local community and shaping the way towards reaching a consensus.

  20. Incorporating Ecosystem Function Concept in Environmental Planning and Decision Making by Means of Multi-Criteria Evaluation: The Case-Study of Kalloni, Lesbos, Greece

    NASA Astrophysics Data System (ADS)

    Oikonomou, Vera; Dimitrakopoulos, Panayiotis G.; Troumbis, Andreas Y.

    2011-01-01

    Nature provides life-support services which do not merely constitute the basis for ecosystem integrity but also benefit human societies. The importance of such multiple outputs is often ignored or underestimated in environmental planning and decision making. The economic valuation of ecosystem functions or services has been widely used to make these benefits economically visible and thus address this deficiency. Alternatively, the relative importance of the components of ecosystem value can be identified and compared by means of multi-criteria evaluation. Hereupon, this article proposes a conceptual framework that couples ecosystem function analysis, multi criteria evaluation and social research methodologies for introducing an ecosystem function-based planning and management approach. The framework consists of five steps providing the structure of a participative decision making process which is then tested and ratified, by applying the discrete multi-criteria method NAIADE, in the Kalloni Natura 2000 site, on Lesbos, Greece. Three scenarios were developed and evaluated with regard to their impacts on the different types of ecosystem functions and the social actors' value judgements. A conflict analysis permitted the better elaboration of the different views, outlining the coalitions formed in the local community and shaping the way towards reaching a consensus.

  1. Incorporating ecosystem function concept in environmental planning and decision making by means of multi-criteria evaluation: the case-study of Kalloni, Lesbos, Greece.

    PubMed

    Oikonomou, Vera; Dimitrakopoulos, Panayiotis G; Troumbis, Andreas Y

    2011-01-01

    Nature provides life-support services which do not merely constitute the basis for ecosystem integrity but also benefit human societies. The importance of such multiple outputs is often ignored or underestimated in environmental planning and decision making. The economic valuation of ecosystem functions or services has been widely used to make these benefits economically visible and thus address this deficiency. Alternatively, the relative importance of the components of ecosystem value can be identified and compared by means of multi-criteria evaluation. Hereupon, this article proposes a conceptual framework that couples ecosystem function analysis, multi criteria evaluation and social research methodologies for introducing an ecosystem function-based planning and management approach. The framework consists of five steps providing the structure of a participative decision making process which is then tested and ratified, by applying the discrete multi-criteria method NAIADE, in the Kalloni Natura 2000 site, on Lesbos, Greece. Three scenarios were developed and evaluated with regard to their impacts on the different types of ecosystem functions and the social actors' value judgements. A conflict analysis permitted the better elaboration of the different views, outlining the coalitions formed in the local community and shaping the way towards reaching a consensus. PMID:20953785

  2. Slavery in the 19th Century: A Unit of Study for Grades 5-8.

    ERIC Educational Resources Information Center

    Pearson, Jim; Robertson, John

    This unit is one of a series that presents specific moments in history from which students focus on the meanings of landmark events. The lessons included in this unit attempt to make slavery comprehensible to students, showing its oppressiveness and yet explaining how white Southern culture rationalized and sustained it. The unit also explains how…

  3. Consumer in the Marketplace. An Interdisciplinary Approach to Consumer Education. Developed for Grades 5-8.

    ERIC Educational Resources Information Center

    Allegheny Intermediate Unit, Pittsburgh, PA.

    This manual identifies activities and resources for infusing consumer education into English, social studies, science, mathematics, and home economics courses in grades five through eight. The activities are intended to help students recognize their rights and responsibilities as consumers in our society and make intelligent decisions in light of…

  4. Incorporating GIS data into an agent-based model to support planning policy making for the development of creative industries

    NASA Astrophysics Data System (ADS)

    Liu, Helin; Silva, Elisabete A.; Wang, Qian

    2016-07-01

    This paper presents an extension to the agent-based model "Creative Industries Development-Urban Spatial Structure Transformation" by incorporating GIS data. Three agent classes, creative firms, creative workers and urban government, are considered in the model, and the spatial environment represents a set of GIS data layers (i.e. road network, key housing areas, land use). With the goal to facilitate urban policy makers to draw up policies locally and optimise the land use assignment in order to support the development of creative industries, the improved model exhibited its capacity to assist the policy makers conducting experiments and simulating different policy scenarios to see the corresponding dynamics of the spatial distributions of creative firms and creative workers across time within a city/district. The spatiotemporal graphs and maps record the simulation results and can be used as a reference by the policy makers to adjust land use plans adaptively at different stages of the creative industries' development process.

  5. Methodology of environmental diagnosis for construction and demolition waste landfills: a tool for planning and making decisions.

    PubMed

    Garrido, E; Calvo, F; Ramos, A F; Zamorano, M

    2005-11-01

    Current legislation in the European Union regarding landfills provides measures, procedures and guidance to prevent or reduce, insofar as possible, negative effects on the environment. This means that Member States must take measures so that landfills cannot operate unless the operator first presents a plan for the site, which includes the implementation of improvements considered necessary by the engineer for compliance with regulations. Researchers at the University of Granada have developed a method to ascertain the degree of environmental impact that a construction and demolition waste landfill may produce on its immediate surroundings. This methodology is based on environmental indexes; its objective is to give crucial information concerning possible environmental problems produced by a landfill. The data thus obtained will permit the elaboration of guidelines for improvements in the location, design, and operation of landfills, or in extreme cases, their dosing, sealing, and rehabilitation.

  6. Knowledge translation strategies to improve the use of evidence in public health decision making in local government: intervention design and implementation plan

    PubMed Central

    2013-01-01

    Background Knowledge translation strategies are an approach to increase the use of evidence within policy and practice decision-making contexts. In clinical and health service contexts, knowledge translation strategies have focused on individual behavior change, however the multi-system context of public health requires a multi-level, multi-strategy approach. This paper describes the design of and implementation plan for a knowledge translation intervention for public health decision making in local government. Methods Four preliminary research studies contributed findings to the design of the intervention: a systematic review of knowledge translation intervention effectiveness research, a scoping study of knowledge translation perspectives and relevant theory literature, a survey of the local government public health workforce, and a study of the use of evidence-informed decision-making for public health in local government. A logic model was then developed to represent the putative pathways between intervention inputs, processes, and outcomes operating between individual-, organizational-, and system-level strategies. This formed the basis of the intervention plan. Results The systematic and scoping reviews identified that effective and promising strategies to increase access to research evidence require an integrated intervention of skill development, access to a knowledge broker, resources and tools for evidence-informed decision making, and networking for information sharing. Interviews and survey analysis suggested that the intervention needs to operate at individual and organizational levels, comprising workforce development, access to evidence, and regular contact with a knowledge broker to increase access to intervention evidence; develop skills in appraisal and integration of evidence; strengthen networks; and explore organizational factors to build organizational cultures receptive to embedding evidence in practice. The logic model incorporated these

  7. Country planning for health interventions under development: lessons from the malaria vaccine decision-making framework and implications for other new interventions.

    PubMed

    Brooks, Alan; Ba-Nguz, Antoinette

    2012-05-01

    Traditionally it has taken years or decades for new public health interventions targeting diseases found in developing countries to be accessible to those most in need. One reason for the delay has been insufficient anticipation of the eventual processes and evidence required for decision making by countries. This paper describes research into the anticipated processes and data needed to inform decision making on malaria vaccines, the most advanced of which is still in phase 3 trials. From 2006 to 2008, a series of country consultations in Africa led to the development of a guide to assist countries in preparing their malaria vaccine decision-making frameworks. The guide builds upon the World Health Organization's Vaccine Introduction Guidelines. It identifies the processes and data for decisions, when they would be needed relative to the development timelines of the intervention, and where they will come from. Policy development will be supported by data (e.g. malaria disease burden; roles of other malaria interventions; malaria vaccine impact; economic and financial issues; malaria vaccine efficacy, quality and safety) as will implementation decisions (e.g. programmatic issues and socio-cultural environment). This generic guide can now be applied to any future malaria vaccine. The paper discusses the opportunities and challenges to early planning for country decision-making-from the potential for timely, evidence-informed decisions to the risks of over-promising around an intervention still under development. Careful and well-structured planning by countries is an important way to ensure that new interventions do not remain unused for years or decades after they become available.

  8. Intelligent behavior generator for autonomous mobile robots using planning-based AI decision making and supervisory control logic

    NASA Astrophysics Data System (ADS)

    Shah, Hitesh K.; Bahl, Vikas; Martin, Jason; Flann, Nicholas S.; Moore, Kevin L.

    2002-07-01

    In earlier research the Center for Self-Organizing and Intelligent Systems (CSOIS) at Utah State University (USU) have been funded by the US Army Tank-Automotive and Armaments Command's (TACOM) Intelligent Mobility Program to develop and demonstrate enhanced mobility concepts for unmanned ground vehicles (UGVs). One among the several out growths of this work has been the development of a grammar-based approach to intelligent behavior generation for commanding autonomous robotic vehicles. In this paper we describe the use of this grammar for enabling autonomous behaviors. A supervisory task controller (STC) sequences high-level action commands (taken from the grammar) to be executed by the robot. It takes as input a set of goals and a partial (static) map of the environment and produces, from the grammar, a flexible script (or sequence) of the high-level commands that are to be executed by the robot. The sequence is derived by a planning function that uses a graph-based heuristic search (A* -algorithm). Each action command has specific exit conditions that are evaluated by the STC following each task completion or interruption (in the case of disturbances or new operator requests). Depending on the system's state at task completion or interruption (including updated environmental and robot sensor information), the STC invokes a reactive response. This can include sequencing the pending tasks or initiating a re-planning event, if necessary. Though applicable to a wide variety of autonomous robots, an application of this approach is demonstrated via simulations of ODIS, an omni-directional inspection system developed for security applications.

  9. Fertility Decision-Making Among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning.

    PubMed

    Pintye, Jillian; Ngure, Kenneth; Curran, Kathryn; Vusha, Sophie; Mugo, Nelly; Celum, Connie; Baeten, Jared M; Heffron, Renee

    2015-09-01

    HIV-serodiscordant couples often choose to attempt pregnancy despite their HIV transmission risk. Optimizing delivery of HIV risk reduction strategies during peri-conception periods (i.e., safer conception) requires understanding how HIV-serodiscordant couples approach fertility decisions. We conducted 36 in-depth individual interviews with male and female partners of Kenyan heterosexual HIV-serodiscordant couples who recently conceived. Transcripts were analyzed by gender and HIV serostatus using open coding. Matrices were used to identify patterns and emerging themes. Most participants expressed acceptance of being in an HIV-serodiscordant couple and affirmed their resilience to live with serodiscordance and achieve their fertility goals. Overall, while the goal for childbearing was unchanged, conception became an urgent desire so that both partners could experience childrearing together while the HIV-infected partner was still healthy. Children also add value to the relationship, and multiple children were a commonly expressed desire. Couples' desires dominated those of individual partners in fertility decision-making, but male preferences were more influential when the individual desires differed. Values and preferences of the couple as a unit may mediate fertility decision-making in HIV-discordant couples. Thus, it is important that safer conception programs include both partners when appropriate and consider the relationship context during risk reduction counseling and when recommending risk reduction interventions. PMID:26301703

  10. Fertility Decision-Making Among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning.

    PubMed

    Pintye, Jillian; Ngure, Kenneth; Curran, Kathryn; Vusha, Sophie; Mugo, Nelly; Celum, Connie; Baeten, Jared M; Heffron, Renee

    2015-09-01

    HIV-serodiscordant couples often choose to attempt pregnancy despite their HIV transmission risk. Optimizing delivery of HIV risk reduction strategies during peri-conception periods (i.e., safer conception) requires understanding how HIV-serodiscordant couples approach fertility decisions. We conducted 36 in-depth individual interviews with male and female partners of Kenyan heterosexual HIV-serodiscordant couples who recently conceived. Transcripts were analyzed by gender and HIV serostatus using open coding. Matrices were used to identify patterns and emerging themes. Most participants expressed acceptance of being in an HIV-serodiscordant couple and affirmed their resilience to live with serodiscordance and achieve their fertility goals. Overall, while the goal for childbearing was unchanged, conception became an urgent desire so that both partners could experience childrearing together while the HIV-infected partner was still healthy. Children also add value to the relationship, and multiple children were a commonly expressed desire. Couples' desires dominated those of individual partners in fertility decision-making, but male preferences were more influential when the individual desires differed. Values and preferences of the couple as a unit may mediate fertility decision-making in HIV-discordant couples. Thus, it is important that safer conception programs include both partners when appropriate and consider the relationship context during risk reduction counseling and when recommending risk reduction interventions.

  11. Fertility Decision-Making Among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning

    PubMed Central

    Pintye, Jillian; Ngure, Kenneth; Curran, Kathryn; Vusha, Sophie; Mugo, Nelly; Celum, Connie; Baeten, Jared M.

    2015-01-01

    Abstract HIV-serodiscordant couples often choose to attempt pregnancy despite their HIV transmission risk. Optimizing delivery of HIV risk reduction strategies during peri-conception periods (i.e., safer conception) requires understanding how HIV-serodiscordant couples approach fertility decisions. We conducted 36 in-depth individual interviews with male and female partners of Kenyan heterosexual HIV-serodiscordant couples who recently conceived. Transcripts were analyzed by gender and HIV serostatus using open coding. Matrices were used to identify patterns and emerging themes. Most participants expressed acceptance of being in an HIV-serodiscordant couple and affirmed their resilience to live with serodiscordance and achieve their fertility goals. Overall, while the goal for childbearing was unchanged, conception became an urgent desire so that both partners could experience childrearing together while the HIV-infected partner was still healthy. Children also add value to the relationship, and multiple children were a commonly expressed desire. Couples' desires dominated those of individual partners in fertility decision-making, but male preferences were more influential when the individual desires differed. Values and preferences of the couple as a unit may mediate fertility decision-making in HIV-discordant couples. Thus, it is important that safer conception programs include both partners when appropriate and consider the relationship context during risk reduction counseling and when recommending risk reduction interventions. PMID:26301703

  12. Rupture process and stress drop of the 2011 Mw 5.8 Virginia earthquake based on seismic waveforms

    NASA Astrophysics Data System (ADS)

    Shao, G.; Crempien, J.; Archuleta, R. J.; Ji, C.

    2011-12-01

    On 23 August 2011, a Mw 5.8 earthquake hit central Virginia. It was reported as the most widely felt earthquake in US history- reflecting, in part, the population density in the eastern US and the low attenuation of this region. We have looked at the rupture process with teleseismic data. We constrain the source rupture process by modeling teleseismic P waves (up to 2Hz) at 43 stations and SH waves (up to 1Hz) at 22 stations. Given the regional trend of the geology we prefer a fault plane that has a strike of 26° and dip of 55° based on the St. Louis regional CMT solution. We use a 9 km x 9 km planar fault plane and a hypocenter depth of 5 km. Maximum slip of our preferred model is 1.05 m, occurring 1-2 km up-dip of the hypocenter. Most of the stress drop (inferred from the slip distribution) is confined to an area that is 5 km down dip and 7 km along strike. The initial results suggest a weak nucleation followed by a relatively slow rupture propagation. The average rupture velocity is ~ 1.9 km/s with almost all of the slip occurring within the 2 s window from 0.6 s to 2.6 s after the origin time. We find a total seismic moment of 5.75x1017 Nm, consistent with the Global CMT solution. Using the slip on the fault we compute an average stress drop of 6.1 MPa, which is consistent with the stress drop from the Eshelby formula for a circular fault of radius 3.4 km and seismic moment of 5.75x1017 Nm. However, analysis of the S wave spectrum from the accelerogram recorded at CBN (Fredericksburg Observatory, Virginia; 58 km epicentral distance) suggests a stress drop on the order of 30 MPa. We plan to present a set of source parameters that are consistent with both the regional and teleseismic data.

  13. 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition.

    PubMed

    Nepali, Kunal; Kumar, Sunil; Huang, Hsiang-Ling; Kuo, Fei-Chiao; Lee, Cheng-Hsin; Kuo, Ching-Chuan; Yeh, Teng-Kuang; Li, Yu-Hsuan; Chang, Jang-Yang; Liou, Jing-Ping; Lee, Hsueh-Yun

    2016-01-14

    This study reports the synthesis of a series of 2-aroylquinoline-5,8-diones (11-23) on the basis of scaffold hopping. The presence of a methoxy group at C6 assists the highly regioselective incorporation with various amines, and simplifies the structural identification process. Among the synthetic compounds, 6-dimethylamino-2-(3,4,5-trimethoxybenzoyl)-quinoline-5,8-dione (12) and 7-pyrrolidin-1-yl-2-(3,4,5-trimethoxybenzoyl)-quinoline-5,8-dione (23) exhibit remarkable anti-proliferative activity against the cancer cell lines tested with mean IC50 values of 0.14 and 0.27 μM, respectively. Compound 23 showed moderate inhibitory activity against tubulin polymerization with an IC50 value of 5.9 μM. In a western blot analysis, 23 caused induction of HSP70 and degradation of Akt, revealing that it possesses HSP90 inhibitory activity.

  14. Comparative physical mapping of the 18S-5.8S-26S rDNA in three sorghum species.

    PubMed

    Sang, Y; Liang, G H

    2000-10-01

    The physical locations of the 18S-5.8S-26S rDNA sequences were examined in three sorghum species by fluorescence in situ hybridization (FISH) using biotin-labeled heterologous 18S-5.8S-26S rDNA probe (pTa71). Each 18S-5.8S-26S rDNA locus occurred at two sites on the chromosomes in Sorghum bicolor (2n = 20) and S. versicolor (2n = 10), but at four sites on the chromosomes of S. halepense (2n = 40) and the tetraploid S. versicolor (2n = 20). Positions of the rDNA loci varied from the interstitial to terminal position among the four accessions of the three sorghum species. The rDNA data are useful for investigation of chromosome evolution and phylogeny. This study excluded S. versicolor as the possible progenitor of S. bicolor.

  15. Intramolecular [2 + 2] photocycloaddition/thermal fragmentation: formally "allowed" and "forbidden"pathways toward 5-8-5 ring systems.

    PubMed

    Bader, Scott J; Snapper, Marc L

    2005-02-01

    The thermal fragmentation of highly functionalized, linear polycyclobutanes with a cis,syn,cis-relative stereochemistry is shown to offer a rapid entry into the dicyclopenta[a,d]cyclooctenyl (5-8-5) ring system. The thermolysis of polyfused cyclobutanes with a cis,syn,cis- or a cis,anti,cis-relationship proceeds in a formally "symmetry-allowed" manner through the intermediacy of a cis,trans-cyclooctadiene. When a bridging tether used to establish the cis,syn,cis-stereochemistry in the intramolecular [2 + 2] photocyclization is present in the thermolysis step, however, the result of a formally "symmetry-forbidden" fragmentation is observed yielding cis,cis-cyclooctadiene-containing 5-8-5 products. In general, the stereochemical observations noted in these fragmentations offer new opportunities for accessing a variety of stereochemical relationships in these 5-8-5 ring systems.

  16. Design of 4x1 microstrip patch antenna array for 5.8 GHz ISM band applications

    NASA Astrophysics Data System (ADS)

    Valjibhai, Gohil Jayesh; Bhatia, Deepak

    2013-01-01

    This paper describes the new design of four element antenna array using corporate feed technique. The proposed antenna array is developed on the Rogers 5880 dielectric material. The antenna array works on 5.8 GHz ISM band. The industrial, scientific and medical (ISM) radio bands are radio bands (portions of the radio spectrum) reserved internationally for the use of radio frequency (RF) energy for industrial, scientific and medical purposes other than communications. The array antennas have VSWR < 1.6 from 5.725 - 5.875 GHz. The simulated return loss characteristic of the antenna array is - 39.3 dB at 5.8 GHz. The gain of the antenna array is 12.3 dB achieved. The directivity of the broadside radiation pattern is 12.7 dBi at the 5.8 GHz operating frequency. The antenna array is simulated using High frequency structure simulation software.

  17. Opportunities and strategies to incorporate ecosystem services knowledge and decision support tools into planning and decision making in Hawai'i.

    PubMed

    Bremer, Leah L; Delevaux, Jade M S; Leary, James J K; J Cox, Linda; Oleson, Kirsten L L

    2015-04-01

    Incorporating ecosystem services into management decisions is a promising means to link conservation and human well-being. Nonetheless, planning and management in Hawai'i, a state with highly valued natural capital, has yet to broadly utilize an ecosystem service approach. We conducted a stakeholder assessment, based on semi-structured interviews, with terrestrial (n = 26) and marine (n = 27) natural resource managers across the State of Hawai'i to understand the current use of ecosystem services (ES) knowledge and decision support tools and whether, how, and under what contexts, further development would potentially be useful. We found that ES knowledge and tools customized to Hawai'i could be useful for communication and outreach, justifying management decisions, and spatial planning. Greater incorporation of this approach is clearly desired and has a strong potential to contribute to more sustainable decision making and planning in Hawai'i and other oceanic island systems. However, the unique biophysical, socio-economic, and cultural context of Hawai'i, and other island systems, will require substantial adaptation of existing ES tools. Based on our findings, we identified four key opportunities for the use of ES knowledge and tools in Hawai'i: (1) linking native forest protection to watershed health; (2) supporting sustainable agriculture; (3) facilitating ridge-to-reef management; and (4) supporting statewide terrestrial and marine spatial planning. Given the interest expressed by natural resource managers, we envision broad adoption of ES knowledge and decision support tools if knowledge and tools are tailored to the Hawaiian context and coupled with adequate outreach and training.

  18. Opportunities and Strategies to Incorporate Ecosystem Services Knowledge and Decision Support Tools into Planning and Decision Making in Hawai`i

    NASA Astrophysics Data System (ADS)

    Bremer, Leah L.; Delevaux, Jade M. S.; Leary, James J. K.; J. Cox, Linda; Oleson, Kirsten L. L.

    2015-04-01

    Incorporating ecosystem services into management decisions is a promising means to link conservation and human well-being. Nonetheless, planning and management in Hawai`i, a state with highly valued natural capital, has yet to broadly utilize an ecosystem service approach. We conducted a stakeholder assessment, based on semi-structured interviews, with terrestrial ( n = 26) and marine ( n = 27) natural resource managers across the State of Hawai`i to understand the current use of ecosystem services (ES) knowledge and decision support tools and whether, how, and under what contexts, further development would potentially be useful. We found that ES knowledge and tools customized to Hawai`i could be useful for communication and outreach, justifying management decisions, and spatial planning. Greater incorporation of this approach is clearly desired and has a strong potential to contribute to more sustainable decision making and planning in Hawai`i and other oceanic island systems. However, the unique biophysical, socio-economic, and cultural context of Hawai`i, and other island systems, will require substantial adaptation of existing ES tools. Based on our findings, we identified four key opportunities for the use of ES knowledge and tools in Hawai`i: (1) linking native forest protection to watershed health; (2) supporting sustainable agriculture; (3) facilitating ridge-to-reef management; and (4) supporting statewide terrestrial and marine spatial planning. Given the interest expressed by natural resource managers, we envision broad adoption of ES knowledge and decision support tools if knowledge and tools are tailored to the Hawaiian context and coupled with adequate outreach and training.

  19. Differences in eighth grade science student and teacher perceptions of students' level of input into academic planning and decision making

    NASA Astrophysics Data System (ADS)

    Chapman, Jarrett Michael

    Teachers are expected to improve their planning, instruction, and assessment as they progress through their career. An important component to teachers knowing what to modify in their teaching style is being able to solicit meaningful feedback from students. This mixed-methods study was conducted to provide teachers with a quantitative method to collect data about their teaching using the Constructivist Learning Environment Survey (CLES). Phase 1 allowed students to provide anonymous feedback to their teachers that the teachers could later reflect upon in conjunction with the students' other feedback. Using measures of central tendencies, it was determined that of the five categories of the CLES the area of student negotiation was statistically different from the other categories. While eight teachers had sufficient (n>10) student data to be invited to participate in Phase 2, only five of the teachers choose to participate in a semi-structured interview to further examine the potential differences between teacher and student perception of student negotiation with the curriculum, instruction and assessment that occurs in the classroom. Coding the interview transcripts led to three categories: 1) teaching style (with themes including curriculum, instruction, and assessment, and sub themes of teacher centered and student centered); 2) external pressures (with themes of standards , standardized tests, and socioeconomic conditions); 3) effectiveness of student negotiation (with themes of positive effect or no effect on motivation). The five teachers who participated in Phase 2 had varying levels of awareness and willingness to adjust their classroom curriculum, instruction, and assessment to include student negotiation. All but one teacher, however, saw the value in increasing student negotiation in the classroom and desired to continue to change their teaching to include more student negotiation.

  20. Country planning for health interventions under development: lessons from the malaria vaccine decision-making framework and implications for other new interventions

    PubMed Central

    Brooks, Alan; Ba-Nguz, Antoinette

    2012-01-01

    Traditionally it has taken years or decades for new public health interventions targeting diseases found in developing countries to be accessible to those most in need. One reason for the delay has been insufficient anticipation of the eventual processes and evidence required for decision making by countries. This paper describes research into the anticipated processes and data needed to inform decision making on malaria vaccines, the most advanced of which is still in phase 3 trials. From 2006 to 2008, a series of country consultations in Africa led to the development of a guide to assist countries in preparing their malaria vaccine decision-making frameworks. The guide builds upon the World Health Organization’s Vaccine Introduction Guidelines. It identifies the processes and data for decisions, when they would be needed relative to the development timelines of the intervention, and where they will come from. Policy development will be supported by data (e.g. malaria disease burden; roles of other malaria interventions; malaria vaccine impact; economic and financial issues; malaria vaccine efficacy, quality and safety) as will implementation decisions (e.g. programmatic issues and socio-cultural environment). This generic guide can now be applied to any future malaria vaccine. The paper discusses the opportunities and challenges to early planning for country decision-making—from the potential for timely, evidence-informed decisions to the risks of over-promising around an intervention still under development. Careful and well-structured planning by countries is an important way to ensure that new interventions do not remain unused for years or decades after they become available. PMID:22513733

  1. Process for manufacturing bis(2-methoxyethyl)-2,3,6,7-tetracyano-1,4,5,8,9,10-hexazaanthracene

    DOEpatents

    Rasmussen, Paul George; Lawton, Richard Graham

    2014-06-03

    A process to manufacture substituted tetracyano-hexaazatricyclics with the substitutions occurring at the 9 and 10 hydrogens. The process begins with 2,3-dichloro-5,6-dicyanopyrazine, which is reacted to form the desired tetracyano-hexaazatricyclic. Different process embodiments enable different reaction paths to the desired tetracyano-hexaazatricyclic. Different tetracyano-hexaazatricyclic embodiments include bis(2-methoxyethyl)-2,3,6,7-tetracyano-1,4,5,8,9,10-hexazaanthracene and bis(2-methoxyethoxyethyl)-2,3,6,7-tetracyano-1,4,5,8,9,10-hexazaanthracen- e.

  2. The Study of Success of Individuals with Exceptional Needs in Tennessee Virtual Academy in Grades 5-8

    ERIC Educational Resources Information Center

    Vernon, Nichole

    2013-01-01

    The purpose of this study was to examine the success of students in Exceptional Education in Tennessee Virtual Academy. Students participating in this study are in grades 5-8, have a diagnosis of Specific Learning Disabilities, residents of Tennessee, currently enrolled in Tennessee Virtual Academy, and received Exceptional Education services.…

  3. Into Adolescence: A Menu for Good Health. A Curriculum for Grades 5-8. Contemporary Health Series.

    ERIC Educational Resources Information Center

    Laing, Susan J.

    This module, oriented toward middle school students in grades 5-8, includes nine lessons designed to help students synthesize nutritional information and use it to improve their health. In lesson 1, students look at factors that influence food choices. Lesson 2 uses creative expression activities to help students learn about the role of nutrients.…

  4. International Guidelines on Sexuality Education and Their Relevance to a Contemporary Curriculum for Children Aged 5-8 Years

    ERIC Educational Resources Information Center

    Goldman, Juliette D. G.

    2013-01-01

    This paper evaluates UNESCO's recommended sexuality educational framework for junior school students aged 5-8 years. It also compares it to an existing state-designed Health and Physical Education curriculum that includes sexual and reproductive health for the same cohort. Based on the universal values of respect and human rights,…

  5. Into Adolescence: Learning about HIV. Curriculum for Grades 5-8. Contemporary Health Series. [Teachers' Guide] Revised Edition. Student Workbook.

    ERIC Educational Resources Information Center

    Post, Jory; McPherson, Carole

    Through a variety of learning strategies, this curriculum guide provides an age-appropriate Acquired Immune Deficiency Syndrome (AIDS) education for students grades 5-8. An introduction incorporates curriculum objectives, classroom environment, teacher responsibilities, time, instructional strategies, parental involvement and support, and…

  6. Competency-Based Adult Education Classroom Management Guide for Adult Basic Education Curriculum (Level II, 5-8).

    ERIC Educational Resources Information Center

    Singer, Elizabeth

    This Competency-Based Adult Basic Education (CBABE) Classroom Management Guide was developed to aid the Adult Basic Education (ABE) facilitator in implementing a model CBABE Level 5-8 curriculum. First, introductory material provides background on the CBABE project at Brevard Community College (Florida) and the rationale for the development of the…

  7. Math Around the World: Grades 5-8. Teachers' Guide. Great Explorations in Math and Science (GEMS).

    ERIC Educational Resources Information Center

    Braxton, Beverly; And Others

    This document is a collection of eight games from four continents. Students use mathematics that is directly relevant to them as they take part in the games. The first five games (NIM, Kalah, Tower of Hanoi, Shongo Networks, and Magic Squares) feature presentation instructions that describe multiple-session classroom activities for grades 5-8.…

  8. Equity monitoring for social marketing: use of wealth quintiles and the concentration index for decision making in HIV prevention, family planning, and malaria programs

    PubMed Central

    2013-01-01

    Background The majority of social marketing programs are intended to reach the poor. It is therefore essential that social marketing organizations monitor the health equity of their programs and improve targeting when the poor are not being reached. Current measurement approaches are often insufficient for decision making because they fail to show a program's ability to reach the poor and demonstrate progress over time. Further, effective program equity metrics should be benchmarked against a national reference population and consider exposure, not just health outcomes, to measure direct results of implementation. This study compares two measures of health equity, concentration indices and wealth quintiles, using a defined reference population, and considers benefits of both measures together to inform programmatic decision making. Methods Three datasets from recent cross-sectional behavioral surveys on malaria, HIV, and family planning from Nepal and Burkina Faso were used to calculate concentration indices and wealth quintiles. Each sample was standardized to national wealth distributions based on recent Demographic and Health Surveys. Wealth quintiles were generated and concentration indices calculated for health outcomes and program exposure in each sample. Chi-square and t-tests were used to assess statistical significance of results. Results Reporting wealth quintiles showed that recipients of Population Services International (PSI) interventions were wealthier than national populations. Both measures indicated that desirable health outcomes were usually concentrated among wealthier populations. Positive and significant concentration indices in all three surveys indicated that wealth and program exposure were correlated; however this relationship was not necessarily linear. In analyzing the equity of modern contraceptive use stratified by exposure to family planning messages in Nepal, the outcome was equitable (concentration index = 0.006, p = 0.68) among the

  9. Addition polymers from 1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene and Bis-dienes. 2: Evidence for thermal dehydration occurring in the cure process

    NASA Technical Reports Server (NTRS)

    Meador, Mary Ann B.; Olshavsky, Michael A.; Meador, Michael A.; Ahn, Myong-Ku

    1988-01-01

    Diels-Alder cycloaddition copolymers from 1,4,5,8-tetrahydro-1,4;5,8-diepoxyanthracene and anthracene end-capped polyimide oligomers appear, by thermogravimetric analysis (TGA), to undergo dehydration at elevated temperatures. This would produce thermally stable pentiptycene units along the polymer backbone, and render the polymers incapable of unzipping through a retro-Diels-Alder pathway. High resolution solid 13C nuclear magnetic resonance (NMR) of one formulation of the polymer system before and after heating at elevated temperatures, shows this to indeed be the case. NMR spectra of solid samples of the polymer before and after heating correlated well with those of the parent pentiptycene model compound before and after acid-catalyzed dehydration. Isothermal gravimetric analyses and viscosities of the polymer before and after heat treatment support dehydration as a mechanism for the cure reaction.

  10. Gallic acid inhibits vascular calcification through the blockade of BMP2-Smad1/5/8 signaling pathway.

    PubMed

    Kee, Hae Jin; Cho, Soo-Na; Kim, Gwi Ran; Choi, Sin Young; Ryu, Yuhee; Kim, In Kyeom; Hong, Young Joon; Park, Hyung Wook; Ahn, Youngkeun; Cho, Jeong Gwan; Park, Jong Chun; Jeong, Myung Ho

    2014-11-01

    Vascular calcification is associated with increased risk of morbidity and mortality in patients with cardiovascular diseases, chronic kidney diseases, and diabetes. Gallic acid, a natural compound found in gallnut and green tea, is known to be antifungal, antioxidant, and anticancer. Here we investigated the effect of gallic acid on vascular smooth muscle cell (VSMC) calcification and the underlying mechanism. Gallic acid inhibited inorganic phosphate-induced osteoblast differentiation markers as well as calcification phenotypes (as determined by calcium deposition, Alizarin Red, and Von Kossa staining). Knockdown of BMP2 or Noggin blocked phosphate-induced calcification. Gallic acid suppressed phosphorylation of Smad1/5/8 protein induced by inorganic phosphate. Taken together, we suggest that gallic acid acts as a novel therapeutic agent of vascular calcification by mediating BMP2-Smad1/5/8 signaling pathway.

  11. An ameliorative protocol for the quantification of purine 5',8-cyclo-2'-deoxynucleosides in oxidized DNA

    NASA Astrophysics Data System (ADS)

    Terzidis, Michael; Chatgilialoglu, Chryssostomos

    2015-07-01

    5',8-Cyclo-2'-deoxyadenosine (cdA) and 5',8-cyclo-2'-deoxyguanosine (cdG) are lesions resulting from hydroxyl radical (HO•) attack on the 5'H of the nucleoside sugar moiety and exist in both 5'R and 5'S diastereomeric forms. Increased levels of cdA and cdG are linked to Nucleotide Excision Repair mechanism deficiency and mutagenesis. Discrepancies in the damage measurements reported over recent years indicated the weakness of the actual protocols, in particular for ensuring the quantitative release of these lesions from the DNA sample and the appropriate method for their analysis. Herein we report the detailed revision leading to a cost-effective and efficient protocol for the DNA damage measurement, consisting of the nuclease benzonase and nuclease P1 enzymatic combination for DNA digestion followed by liquid chromatography isotope dilution tandem mass spectrometry analysis.

  12. Selective excavation of human carious dentin using the nanosecond pulsed laser in 5.8-μm wavelength range

    NASA Astrophysics Data System (ADS)

    Kita, Tetsuya; Ishii, Katsunori; Yoshikawa, Kazushi; Yasuo, Kenzo; Yamamoto, Kazuyo; Awazu, Kunio

    Less-invasive treatment of caries has been needed in laser dentistry. Based on the absorption property of dentin substrates, 6 μm wavelength range shows specific absorptions and promising characteristics for the excavation. In our previous study, 5.8 μm wavelength range was found to be effective for selective excavation of carious dentin and restoration treatment using composite resin from the irradiation experiment with bovine sound and demineralized dentin. In this study, the availability of 5.8 μm wavelength range for selective excavation of human carious dentin was investigated for clinical application. A mid-infrared tunable nanosecond pulsed laser by difference-frequency generation was used for revealing the ablation property of human carious dentin. Irradiation experiments indicated that the wavelength of 5.85 μm and the average power density of 30 W/cm2 realized the selective excavation of human carious dentin, but ablation property was different with respect to each sample because of the different caries progression. In conclusion, 5.8 μm wavelength range was found to be effective for selective excavation of human carious dentin.

  13. Scenario Planning: A Phenomenological Examination of Influence on Organizational Learning and Decision-Making in a K-12 Public Education System

    ERIC Educational Resources Information Center

    Deklotz, Patricia F.

    2013-01-01

    Organizations commonly engage in long range planning to direct decisions. Scenario planning, one method of private sector planning, is recognized as useful when organizations are facing uncertainty. Scenario planning engages the organization in a process that produces plausible stories, called scenarios, describing the organization in several…

  14. Family group conferencing in youth care: characteristics of the decision making model, implementation and effectiveness of the Family Group (FG) plans

    PubMed Central

    2014-01-01

    Background The model of Family group-conferencing (FG-c) for decision making in child welfare has rapidly spread over the world during the past decades. Its popularity is likely to be caused by its philosophy, emphasizing participation and autonomy of families, rather than based on positive research outcomes. Conclusive evidence regarding the (cost) effectiveness of FG-c is not yet available. The aim of this protocol is to describe the design of a study to evaluate the (cost) effectiveness of FG-c as compared to Treatment as Usual. Method/Design The effectiveness of FG-c will be examined by means of a Randomized Controlled Trial. A multi-informant approach will be used to assess child safety as the primary outcome, and commitment of the social network, perceived control/ empowerment; family functioning and use of professional care as secondary outcomes. Implementation of FG-c, characteristics of family manager and family will be examined as moderators of effectiveness. Discussion Studying the effectiveness of Fg-c is crucial now the method is being implemented all over the world as a decision making model in child and youth care. Policy makers should be informed whether the ideals of participation in society and the right for self-determination indeed result in more effective care plans, and the money spent on FG-c is warranted. Trial registration Dutch Trial Register number NTR4320. The design of this study is approved by the independent Ethical Committee of the Faculty of Social and Behavioral Sciences of The University of Amsterdam (approval number: 2013-POWL-3308). This study is financially supported by a grant from ZonMw, The Netherlands Organization for Health Research and Development, grant number: 70-72900-98-13158. PMID:24517167

  15. Oxidation behavior of Mn and Mo alloyed Fe-16Ni-(5-8)Cr-3. 2Si-1. 0Al

    SciTech Connect

    Rawers, J.C.; Oh, J.M.; Dunning, J. )

    1990-02-01

    Oxidation tests were conducted on a master alloy, Fe-16Ni-(5-8)Cr-3Si-1Al, to which (0-4) wt/o pct Mn and/or Mo were added. Tests were conducted at temperatures ranging from 1,073-1,273 K for times up to 1,000 hr. Additions of Mn resulted in formation of a dual oxide structure and decreased oxidation protection. Addition of Mo significantly improved oxidation protection by formation of an intermetallic Fe(Mo)Si precipitate that eventually formed a protective SiO{sub 2} oxide sublayer. The oxidation protection was related to the alloy components and concentration.

  16. ANNUS MIRABILIS. PHYSICS OF OUR DAYS: Geometry and Physics after 100 Years of Einstein's Relativity (5-8 April 2005)

    NASA Astrophysics Data System (ADS)

    Braginsky, Vladimir B.

    2005-06-01

    As part of the celebration of the World Year of Physics, the Conference "Geometry and Physics after 100 Years of Einstein's Relativity" was held in Golm, near Potsdam, Germany, on April 5-8, 2005. The Conference was organized by the Max Planck Institute for Gravitational Physics (also known as the Albert Einstein Institute), which is celebrating its 10th anniversary in 2005. Conference participants discussed progress made in theoretical and experimental research during the 100 years since the publication of Einstein's famous papers in 1905, the year which has gone down in history as 'Albert Einstein's ANNUS MIRABILIS'.

  17. Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo.

    PubMed

    Piacentino, Michael L; Chung, Oliver; Ramachandran, Janani; Zuch, Daniel T; Yu, Jia; Conaway, Evan A; Reyna, Arlene E; Bradham, Cynthia A

    2016-04-01

    Skeletal patterning in the sea urchin embryo requires coordinated signaling between the pattern-dictating ectoderm and the skeletogenic primary mesenchyme cells (PMCs); recent studies have begun to uncover the molecular basis for this process. Using an unbiased RNA-Seq-based screen, we have previously identified the TGF-ß superfamily ligand, LvBMP5-8, as a skeletal patterning gene in Lytechinus variegatus embryos. This result is surprising, since both BMP5-8 and BMP2/4 ligands have been implicated in sea urchin dorsal-ventral (DV) and left-right (LR) axis specification. Here, we demonstrate that zygotic LvBMP5-8 is required for normal skeletal patterning on the left side, as well as for normal PMC positioning during gastrulation. Zygotic LvBMP5-8 is required for expression of the left-side marker soxE, suggesting that LvBMP5-8 is required for left-side specification. Interestingly, we also find that LvBMP5-8 knockdown suppresses serotonergic neurogenesis on the left side. While LvBMP5-8 overexpression is sufficient to dorsalize embryos, we find that zygotic LvBMP5-8 is not required for normal DV specification or development. In addition, ectopic LvBMP5-8 does not dorsalize LvBMP2/4 morphant embryos, indicating that, in the absence of BMP2/4, BMP5-8 is insufficient to specify dorsal. Taken together, our data demonstrate that zygotic LvBMP5-8 signaling is essential for left-side specification, and for normal left-side skeletal and neural patterning, but not for DV specification. Thus, while both BMP2/4 and BMP5-8 regulate LR axis specification, BMP2/4 but not zygotic BMP5-8 regulates DV axis specification in sea urchin embryos. PMID:26905309

  18. Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo.

    PubMed

    Piacentino, Michael L; Chung, Oliver; Ramachandran, Janani; Zuch, Daniel T; Yu, Jia; Conaway, Evan A; Reyna, Arlene E; Bradham, Cynthia A

    2016-04-01

    Skeletal patterning in the sea urchin embryo requires coordinated signaling between the pattern-dictating ectoderm and the skeletogenic primary mesenchyme cells (PMCs); recent studies have begun to uncover the molecular basis for this process. Using an unbiased RNA-Seq-based screen, we have previously identified the TGF-ß superfamily ligand, LvBMP5-8, as a skeletal patterning gene in Lytechinus variegatus embryos. This result is surprising, since both BMP5-8 and BMP2/4 ligands have been implicated in sea urchin dorsal-ventral (DV) and left-right (LR) axis specification. Here, we demonstrate that zygotic LvBMP5-8 is required for normal skeletal patterning on the left side, as well as for normal PMC positioning during gastrulation. Zygotic LvBMP5-8 is required for expression of the left-side marker soxE, suggesting that LvBMP5-8 is required for left-side specification. Interestingly, we also find that LvBMP5-8 knockdown suppresses serotonergic neurogenesis on the left side. While LvBMP5-8 overexpression is sufficient to dorsalize embryos, we find that zygotic LvBMP5-8 is not required for normal DV specification or development. In addition, ectopic LvBMP5-8 does not dorsalize LvBMP2/4 morphant embryos, indicating that, in the absence of BMP2/4, BMP5-8 is insufficient to specify dorsal. Taken together, our data demonstrate that zygotic LvBMP5-8 signaling is essential for left-side specification, and for normal left-side skeletal and neural patterning, but not for DV specification. Thus, while both BMP2/4 and BMP5-8 regulate LR axis specification, BMP2/4 but not zygotic BMP5-8 regulates DV axis specification in sea urchin embryos.

  19. Neglecting the Importance of the Decision Making and Care Regimes of Personal Support Workers: A Critique of Standardization of Care Planning through the RAI/MDS

    ERIC Educational Resources Information Center

    Kontos, Pia C.; Miller, Karen-Lee; Mitchell, Gail J.

    2010-01-01

    Purpose: The Resident Assessment Instrument-Minimum Data Set (RAI/MDS) is an interdisciplinary standardized process that informs care plan development in nursing homes. This standardized process has failed to consistently result in individualized care planning, which may suggest problems with content and planning integrity. We examined the…

  20. Broadband carbon monoxide laser system operating in the wavelength range of 2.5 - 8.3 {mu}m

    SciTech Connect

    Andreev, Yu M; Ionin, Andrei A; Kinyaevsky, I O; Klimachev, Yu M; Kozlov, A Yu; Kotkov, A A; Lanskii, G V; Shaiduko, A V

    2013-02-28

    A two-cascade frequency conversion of CO-laser radiation is demonstrated in a single sample of a nonlinear ZnGeP{sub 2} crystal. The crystal is pumped by a repetitively pulsed cryogenic lowpressure CO laser operating on {approx}150 vibration - rotational transitions in the wavelength range 5.0 - 7.5 {mu}m, which corresponds to the frequency range of a half octave. In the first conversion cascade, generation of second harmonic and sum frequencies of various pairs of CO-laser radiation give {approx}350 emission lines in the wavelength range 2.5 - 3.7 {mu}m. In the second cascade, by mixing the radiation converted in the first cascade with the residual radiation of the CO laser we have obtained {approx}90 lines in the range 4.3 - 5.0 {mu}m and more than 80 lines in the range 7.5 - 8.3 {mu}m. Thus, using a single sample of the nonlinear ZnGeP{sub 2} crystal pumped by the radiation of a single CO laser we have produced a source of broadband (more than one and a half octaves) laser radiation, simultaneously operating at {approx}670 lines in the wavelength range 2.5 - 8.3 {mu}m. (lasers)

  1. They know!—Do they? A qualitative study of residents and relatives views on advance care planning, end-of-life care, and decision-making in nursing homes

    PubMed Central

    Bollig, Georg; Gjengedal, Eva; Rosland, Jan Henrik

    2015-01-01

    Background: Residents living in long-term care facilities are a vulnerable population. For many residents, a nursing home is their place of death. Palliative care and end-of-life decisions are important components of their care provision. Aim: To study the views of cognitively able residents and relatives on advance care planning, end-of-life care, and decision-making in nursing homes. Design: A qualitative study with in-depth interviews with nursing home residents and focus group interviews with relatives of nursing home residents. Analysis is based on interpretive description. Setting/participants: In total, 43 informants from nine nursing homes participated in the study (25 nursing home residents and 18 relatives). All included residents had capacity to provide informed consent and lived in long-term care. Results: The main findings of this study were the differing views about decision-making and advance care planning of residents and relatives. Residents do trust relatives and staff to make important decisions for them. The relatives are in contrast insecure about the residents’ wishes and experience decision-making as a burden. The majority of the residents had not participated in advance care planning. None of the residents stated challenges connected to end-of-life care or mentioned the wish for euthanasia. Conclusion: Although most residents seem to be satisfied with decision-making and end-of life care, there is a need for systematic advance care planning. Advance care planning could help to explore future wishes for care and ease decision-making for the relatives, physicians, and staff and should be offered to all cognitively able nursing homes residents. PMID:26396227

  2. Choice Protocol: A Document To Help Plan and Carry Out Meetings between Persons with Disabilities and Those Who Are Responsible for Assisting Them in Making Choices about Their Future Services.

    ERIC Educational Resources Information Center

    1991

    This protocol is designed to help plan and carry out meetings between persons with disabilities and those who are responsible for assisting them in making choices about their future services. It was developed to quantify and define some of the issues involved in having Illinois individuals who are eligible for relocation from nursing facilities…

  3. 1,3,5,8-tetrahydroxyxanthone regulates ANGPTL3-LPL pathway to lessen the ketosis in mice.

    PubMed

    Xiao, Hong-Bo; Sun, Zhi-Liang; Zhou, Nan

    2012-05-12

    Ketosis is a metabolic disorder closely associated with both lipid and carbohydrate metabolism. Recent studies show that angiopoietin-like protein 3 (ANGPTL3) contributes to the development of metabolic disorder. The objective of this study was to explore the inhibitory effect of 1,3,5,8-tetrahydroxyxanthone (Xan), a naturally occurring flavonoid compound, on ketosis and the mechanisms involved in this regulation. After 4weeks, Xan (10 or 30mg/kg, intragastrically) treatment decreased plasma total ketone bodies, malondialdehyde, 8-isoprostane, triglyceride, total cholesterol levels, and hepatic ANGPTL3 expression concomitantly with increased plasma glucose concentration and adipose lipoprotein lipase (LPL) expression in ketosis murine. The present results suggest that Xan regulates ANGPTL3-LPL pathway to lessen the ketosis in mice.

  4. Loop mediated isothermal amplification of 5.8S rDNA for specific detection of Tritrichomonas foetus.

    PubMed

    Oyhenart, Jorge; Martínez, Florencia; Ramírez, Rosana; Fort, Marcelo; Breccia, Javier D

    2013-03-31

    Tritrichomonas foetus is the causative agent of bovine trichomonosis, a sexually transmitted disease leading to infertility and abortion. A test based on loop mediated isothermal amplification (LAMP) targeting the 5.8S rDNA subunit was designed for the specific identification of T. foetus. The LAMP assay was validated using 28 T. foetus and 35 non-T. foetus trichomonads strains. It did not exhibit cross-reaction with closely related parasites commonly found in smegma cultures like Tetratrichomonas spp. and Pentatrichomonas hominis. Bovine smegma did not show interferences for the detection of the parasite and, the sensitivity of the method (4×10(3) CFU/mL, approximately 10 cells/reaction) was slightly higher than that found for PCR amplification with TFR3 and TFR4 primers. The LAMP approach has potential applications for diagnosis and control of T. foetus and, practical use for low skill operators in rural areas.

  5. Experimental Investigation of the Low-Speed Aerodynamic Characteristics of a 5.8-Percent Scale Hybrid Wing Body Configuration

    NASA Technical Reports Server (NTRS)

    Gatlin, Gregory M.; Vicroy, Dan D.; Carter, Melissa B.

    2012-01-01

    A low-speed experimental investigation has been conducted on a 5.8-percent scale Hybrid Wing Body configuration in the NASA Langley 14- by 22-Foot Subsonic Tunnel. This Hybrid Wing Body (HWB) configuration was designed with specific intention to support the NASA Environmentally Responsible Aviation (ERA) Project goals of reduced noise, emissions, and fuel burn. This HWB configuration incorporates twin, podded nacelles mounted on the vehicle upper surface between twin vertical tails. Low-speed aerodynamic characteristics were assessed through the acquisition of force and moment, surface pressure, and flow visualization data. Longitudinal and lateral-directional characteristics were investigated on this multi-component model. The effects of a drooped leading edge, longitudinal flow-through nacelle location, vertical tail shape and position, elevon deflection, and rudder deflection have been studied. The basic configuration aerodynamics, as well as the effects of these configuration variations, are presented in this paper.

  6. 5,8,11,14-Eicosatetraynoic acid-induced destruction of mitochondria in human prostate cells (PC-3).

    SciTech Connect

    Anderson, K. M.; Seed, T. M.; Wilson, D. E.; Harris, J. E.; Biological and Medical Research; Rush Medical Coll.

    1992-01-01

    Culturing human prostate PC-3 cells for 4, 24, or 72 h in the presence of 5,8,11,14-eicosatetraynoic acid (ETYA), an inhibitor of arachidonic acid metabolism and cholesterol biosynthesis, markedly altered the morphology and reduced the number of mitochondria in the treated cells. Using quantitative electron microscopic morphometry, we documented changes in the number, form, area, matrix density, and integrity of the cristae and limiting membranes of mitochondria in cells cultured with ETYA. The inhibition of cholesterol synthesis or the substitution of ETYA for polyunsaturated fatty acids in the inner membrane may participate in the disruption of the mitochondria, which resembles the morphologic sequelae of oxidative stress. If sufficiently extensive, these changes could contribute to the inhibition of cellular proliferation by ETYA.

  7. Making a Difference in Research and Practice: A Commentary on "Consulting to Facilitate Planned Organizational Change in Schools," an Article by Joseph E. Zins and Robert J. Illback

    ERIC Educational Resources Information Center

    Flaspohler, Paul D.

    2007-01-01

    Zins and Illback observed in 1995 that planned organizational change processes were neglected in practice, training, and research. In the decade following publication of their article, implementation of processes and structures of planned organizational change increased dramatically. Schools and school districts continue to face increased…

  8. Assessing the health equity impacts of regional land-use plan making: An equity focussed health impact assessment of alternative patterns of development of the Whitsunday Hinterland and Mackay Regional Plan, Australia (Short report)

    SciTech Connect

    Gunning, Colleen; Harris, Patrick; Mallett, John

    2011-07-15

    Health service and partners completed an equity focussed health impact assessment to influence the consideration of health and equity within regional land-use planning in Queensland, Australia. This project demonstrated how an equity oriented assessment matrix can assist in testing regional planning scenarios. It is hoped that this HIA will contribute to the emerging interest in ensuring that potential differential health impacts continue to be considered as part of land-use planning processes.

  9. Advanced Planning.

    ERIC Educational Resources Information Center

    Lupinacci, Jeffrey A.

    2000-01-01

    Explains the importance of developing a comprehensive security plan prior to purchasing more equipment and resources to bolster school safety. Decision making following the plan's development is addressed including equipment choices, ID cards, access control, exit alarms, and video monitors. (GR)

  10. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation.

    PubMed

    Liu, Jia; Saito, Kan; Maruya, Yuriko; Nakamura, Takashi; Yamada, Aya; Fukumoto, Emiko; Ishikawa, Momoko; Iwamoto, Tsutomu; Miyazaki, Kanako; Yoshizaki, Keigo; Ge, Lihong; Fukumoto, Satoshi

    2016-01-01

    Bone morphogenetic proteins (BMPs) regulate hard tissue formation, including bone and tooth. Growth differentiation factor 5 (GDF5), a known BMP, is expressed in cartilage and regulates chondrogenesis, and mutations have been shown to cause osteoarthritis. Notably, GDF5 is also expressed in periodontal ligament tissue; however, its role during tooth development is unclear. Here, we used cell culture and in vivo analyses to determine the role of GDF5 during tooth development. GDF5 and its associated BMP receptors are expressed at the protein and mRNA levels during postnatal tooth development, particularly at a stage associated with enamel formation. Furthermore, whereas BMP2 was observed to induce evidently the differentiation of enamel-forming ameloblasts, excess GDF5 induce mildly this differentiation. A mouse model harbouring a mutation in GDF5 (W408R) showed enhanced enamel formation in both the incisors and molars, but not in the tooth roots. Overexpression of the W408R GDF5 mutant protein was shown to induce BMP2-mediated mRNA expression of enamel matrix proteins and downstream phosphorylation of Smad1/5/8. These results suggest that mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-signalling. PMID:27030100

  11. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation

    PubMed Central

    Liu, Jia; Saito, Kan; Maruya, Yuriko; Nakamura, Takashi; Yamada, Aya; Fukumoto, Emiko; Ishikawa, Momoko; Iwamoto, Tsutomu; Miyazaki, Kanako; Yoshizaki, Keigo; Ge, Lihong; Fukumoto, Satoshi

    2016-01-01

    Bone morphogenetic proteins (BMPs) regulate hard tissue formation, including bone and tooth. Growth differentiation factor 5 (GDF5), a known BMP, is expressed in cartilage and regulates chondrogenesis, and mutations have been shown to cause osteoarthritis. Notably, GDF5 is also expressed in periodontal ligament tissue; however, its role during tooth development is unclear. Here, we used cell culture and in vivo analyses to determine the role of GDF5 during tooth development. GDF5 and its associated BMP receptors are expressed at the protein and mRNA levels during postnatal tooth development, particularly at a stage associated with enamel formation. Furthermore, whereas BMP2 was observed to induce evidently the differentiation of enamel-forming ameloblasts, excess GDF5 induce mildly this differentiation. A mouse model harbouring a mutation in GDF5 (W408R) showed enhanced enamel formation in both the incisors and molars, but not in the tooth roots. Overexpression of the W408R GDF5 mutant protein was shown to induce BMP2-mediated mRNA expression of enamel matrix proteins and downstream phosphorylation of Smad1/5/8. These results suggest that mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-signalling. PMID:27030100

  12. Ten Tips for College Planning

    ERIC Educational Resources Information Center

    Goodkin, Susan

    2012-01-01

    Successfully navigating the road from elementary to high school only means that planning for college is the next route on the destination to post-secondary education. With the most elite colleges' acceptance rates hovering around 5-8 percent, it's never too early for parents to start educating themselves and their child about college planning.…

  13. Xenopus Pax-2/5/8 orthologues: novel insights into Pax gene evolution and identification of Pax-8 as the earliest marker for otic and pronephric cell lineages.

    PubMed

    Heller, N; Brändli, A W

    1999-01-01

    Pax genes are a family of transcription factors playing fundamental roles during organogenesis. We have recently demonstrated the expression of Pax-2 during Xenopus embryogenesis [Heller N, Brändli AW (1997): Mech Dev 69: 83-104]. Here we report the cloning and characterization of Xenopus Pax-5 and Pax-8, two orthologues of the Pax-2/5/8 gene family. Molecular phylogenetic analysis indicates that the amphibian Pax-2/5/8 genes are close relatives of their mammalian counterparts and that all vertebrate Pax-2/5/8 genes are derived from a single ancestral gene. Xenopus Pax-2/5/8 genes are expressed in spatially and temporally overlapping patterns during development of at least seven distinct tissues. Most strikingly, Xenopus Pax-8 was identified as the earliest marker of the prospective otic placode and of the intermediate mesoderm, indicating that Pax-8 may play a central role in auditory and excretory system development. Comparison of the expression patterns of fish, amphibian, and mammalian Pax-2/5/8 genes revealed that the tissue specificity of Pax-2/5/8 gene family expression is overall evolutionarily conserved. The expression domains of individual orthologues can however vary in a species-specific manner. For example, the thyroid glands of mammals express Pax-8, while in Xenopus Pax-2 is expressed instead. Our findings indicate that differential silencing of Pax-2/5/8 gene expression may have occurred after the different classes of vertebrates began to evolve separately. PMID:10322629

  14. MONOPTEROS directly activates the auxin-inducible promoter of the Dof5.8 transcription factor gene in Arabidopsis thaliana leaf provascular cells

    PubMed Central

    Konishi, Mineko; Donner, Tyler J.; Scarpella, Enrico; Yanagisawa, Shuichi

    2015-01-01

    MONOPTEROS (MP) is an auxin-responsive transcription factor that is required for primary root formation and vascular development, whereas Dof5.8 is a Dof-class transcription factor whose gene is expressed in embryos as well as the pre- and procambial cells in the leaf primordium in Arabidopsis thaliana. In this study, it is shown that MP directly activates the Dof5.8 promoter. Although no apparent phenotype of the single dof5.8 mutants was found, phenotypic analysis with the mp dof5.8 double mutants revealed that mutations within Dof5.8 enhanced the phenotype of a weak allele of mp, with an increase in the penetrance of the ‘rootless’ phenotype and a reduction in the number of cotyledons. Furthermore, interestingly, although mp mutants showed reduced vascular pattern complexity in cotyledons, the mp dof5.8 double mutants displayed both more simplex and more complex vascular patterns in individual cotyledons. These results imply that the product of Dof5.8 whose expression is regulated by MP at least in part might be involved in multiple processes controlled by MP. PMID:25336688

  15. Summary Report of the Title VI-G Network Third Annual Conference. (Minneapolis, Minnesota, December 5-8, 1977).

    ERIC Educational Resources Information Center

    Network of Innovative Schools, Inc., Andover, MA.

    Presented is the summary report of the Third Annual Conference of the Title VI-G Network which was designed to update learning disability (LD) professionals on pertinent program and education developments, to inform them of future trends and plans, and to offer concrete help in their present work. Introductory sections provide a schedule of the…

  16. Making Best Practices Better

    ERIC Educational Resources Information Center

    Dappolone, Mike

    2013-01-01

    It's easy to make excuses for not integrating technology into classes, and some of these excuses do have merit. If teachers plan on making the effort to overcome these difficulties, they must believe strongly in the strategies they select and stick to them long enough to at least test their effectiveness. Technology use is sometimes referred…

  17. Exploring uncertainty in advance care planning in African Americans: does low health literacy influence decision making preference at end of life.

    PubMed

    Melhado, Lolita; Bushy, Angeline

    2011-11-01

    African Americans over 65 represent 3.5 of the 35.6 million Americans. Morbidity and mortality rates are highest among this group; associated with lack of resources and awareness of health problems. But health needs are the same at end of life, yet care is less than optimal. African Americans are less likely to have advance directives nonetheless desire communication, information, respect, and a trusting doctor-patient relationship. Low health literacy may contribute to this disparity. This scholarly review examines the health literacy in advance care planning and refines concepts of uncertainty in illness theory deriving a model for advance care planning in African Americans.

  18. Exploring uncertainty in advance care planning in African Americans: does low health literacy influence decision making preference at end of life.

    PubMed

    Melhado, Lolita; Bushy, Angeline

    2011-11-01

    African Americans over 65 represent 3.5 of the 35.6 million Americans. Morbidity and mortality rates are highest among this group; associated with lack of resources and awareness of health problems. But health needs are the same at end of life, yet care is less than optimal. African Americans are less likely to have advance directives nonetheless desire communication, information, respect, and a trusting doctor-patient relationship. Low health literacy may contribute to this disparity. This scholarly review examines the health literacy in advance care planning and refines concepts of uncertainty in illness theory deriving a model for advance care planning in African Americans. PMID:21398263

  19. Reduced expression of the mouse ribosomal protein Rpl17 alters the diversity of mature ribosomes by enhancing production of shortened 5.8S rRNA.

    PubMed

    Wang, Minshi; Parshin, Andrey V; Shcherbik, Natalia; Pestov, Dimitri G

    2015-07-01

    Processing of rRNA during ribosome assembly can proceed through alternative pathways but it is unclear whether this could affect the structure of the ribosome. Here, we demonstrate that shortage of a ribosomal protein can change pre-rRNA processing in a way that over time alters ribosome diversity in the cell. Reducing the amount of Rpl17 in mouse cells led to stalled 60S subunit maturation, causing degradation of most of the synthesized precursors. A fraction of pre-60S subunits, however, were able to complete maturation, but with a 5'-truncated 5.8S rRNA, which we named 5.8SC. The 5' exoribonuclease Xrn2 is involved in the generation of both 5.8S(C) and the canonical long form of 5.8S rRNA. Ribosomes containing 5.8S(C) rRNA are present in various mouse and human cells and engage in translation. These findings uncover a previously undescribed form of mammalian 5.8S rRNA and demonstrate that perturbations in ribosome assembly can be a source of heterogeneity in mature ribosomes.

  20. Reduced expression of the mouse ribosomal protein Rpl17 alters the diversity of mature ribosomes by enhancing production of shortened 5.8S rRNA

    PubMed Central

    Wang, Minshi; Parshin, Andrey V.; Shcherbik, Natalia; Pestov, Dimitri G.

    2015-01-01

    Processing of rRNA during ribosome assembly can proceed through alternative pathways but it is unclear whether this could affect the structure of the ribosome. Here, we demonstrate that shortage of a ribosomal protein can change pre-rRNA processing in a way that over time alters ribosome diversity in the cell. Reducing the amount of Rpl17 in mouse cells led to stalled 60S subunit maturation, causing degradation of most of the synthesized precursors. A fraction of pre-60S subunits, however, were able to complete maturation, but with a 5′-truncated 5.8S rRNA, which we named 5.8SC. The 5′ exoribonuclease Xrn2 is involved in the generation of both 5.8SC and the canonical long form of 5.8S rRNA. Ribosomes containing 5.8SC rRNA are present in various mouse and human cells and engage in translation. These findings uncover a previously undescribed form of mammalian 5.8S rRNA and demonstrate that perturbations in ribosome assembly can be a source of heterogeneity in mature ribosomes. PMID:25995445

  1. Icariin regulates systemic iron metabolism by increasing hepatic hepcidin expression through Stat3 and Smad1/5/8 signaling.

    PubMed

    Zhang, Miao; Liu, Jing; Guo, Wenli; Liu, Xin; Liu, Sijin; Yin, Huijun

    2016-05-01

    Systemic iron homeostasis is strictly controlled under normal conditions to ensure a balance between the absorption, utilization, storage and recycling of iron. The hepcidin-ferroportin (FPN) axis is of critical importance in the maintenance of iron homeostasis. Hepcidin deficiency gives rise to enhanced dietary iron absorption, as well as to increased iron release from macrophages, and this in turn results in iron accumulation in the plasma and organs, and is associated with a range of tissue pathologies. Low hepcidin levels have been demonstrated in most forms of hereditary hemochromatosis (HH), as well as in β-thalassemia. Therapies that increase hepcidin concentrations may potentially play a role in the treatment of these iron overload-related diseases. To date, natural compounds have not been extensively investigated for this purpose, to the best of our knowledge. Thus, in the present study, we screened natural compounds that have the potential to regulate hepcidin expression. By performing hepcidin promoter-luciferase assay, RT-qPCR and animal experiments, we demonstrated that icariin and berberine were potent stimulators of hepcidin transcription. Mechanistic experiments indicated that icariin and berberine increased hepcidin expression by activating the signal transducer and activator of transcription 3 (Stat3) and Smad1/5/8 signaling pathways. The induction of hepcidin was confirmed in mice following icariin administration, coupled with associated changes in serum and tissue iron concentrations. In support of these findings, the icariin analogues, epimedin A, B and C, also increased hepatic hepcidin expression. However, these changes were not observed in hepcidin-deficient [Hamp1-/- or Hamp1‑knockout (KO)] mice following icariin administration, thereby verifying hepatic hepcidin as the target of icariin. Although berberine exhibited a robust capacity to promote hepcidin expression in vitro, it failed to alter hepcidin expression in mice. Taken together

  2. Anti-proliferative actions of 2-decylamino-5,8-dimethoxy-1,4-naphthoquinone in vascular smooth muscle cells

    SciTech Connect

    Lee, Jung-Jin; Zhang, Wei-Yun; Yi, Hyoseok; Kim, Yohan; Kim, In-Su; Shen, Gui-Nan; Song, Gyu-Yong; Myung, Chang-Seon

    2011-07-22

    Highlights: {yields} 2-Decylamino-DMNQ inhibited PDGF-BB-induced VSMC proliferation in a dose-dependent manner with no apparent cytotoxicity. {yields} 2-Decylamino-DMNQ inhibited PDGF-BB-induced phosphorylation of Erk1/2 and PLC{gamma}1. {yields} 2-Decylamino-DMNQ arrested a G{sub 0}/G{sub 1} cell cycle progression in association with pRb phosphorylation and PCNA expression. {yields} Both U0126, an Erk inhibitor, and U73122, a PLC{gamma} inhibitor, arrested a G{sub 0}/G{sub 1} phase of the cell cycle. -- Abstract: Naphthoquinone derivatives have been reported to possess various pharmacological activities, such as antiplatelet, anticancer, antifungal, and antiviral properties. In this study, we investigated the effects of a newly-synthesized naphthoquinone derivative, 2-decylamino-5,8-dimethoxy-1,4-naphthoquinone (2-decylamino-DMNQ), on VSMC proliferation and examined the molecular basis of the underlying mechanism. In a dose-dependent manner, 2-decylamino-DMNQ inhibited PDGF-stimulated VSMC proliferation with no apparent cytotoxic effect. While 2-decylamino-DMNQ did not affect PDGF-R{beta} or Akt, it did inhibit the phosphorylation of Erk1/2 and PLC{gamma}1 induced by PDGF. Moreover, 2-decylamino-DMNQ suppressed DNA synthesis through the arrest of cell cycle progression at the G{sub 0}/G{sub 1} phase, including the suppression of pRb phosphorylation and a decrease in PCNA expression, which was related to the downregulation of cell cycle regulatory factors, such as cyclin D1/E and CDK 2/4. It was demonstrated that both U0126, an Erk1/2 inhibitor, and U73122, a PLC{gamma} inhibitor, increased the proportion of cells in the G{sub 0}/G{sub 1} phase of the cell cycle. Thus, these results suggest that 2-decylamino DMNQ has an inhibitory effect on PDGF-induced VSMC proliferation and the mechanism of this action is through cell cycle arrest at the G{sub 0}/G{sub 1} phase. This may be a useful tool for studying interventions for vascular restenosis in coronary

  3. 20 CFR 1002.262 - When is the employer required to make the plan contribution that is attributable to the employee...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... allowed (but not required) to make up his or her missed contributions or elective deferrals. These makeup..., with the repayment period not to exceed five years. Makeup contributions or elective deferrals may...

  4. 20 CFR 1002.262 - When is the employer required to make the plan contribution that is attributable to the employee...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... allowed (but not required) to make up his or her missed contributions or elective deferrals. These makeup..., with the repayment period not to exceed five years. Makeup contributions or elective deferrals may...

  5. 20 CFR 1002.262 - When is the employer required to make the plan contribution that is attributable to the employee...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... allowed (but not required) to make up his or her missed contributions or elective deferrals. These makeup..., with the repayment period not to exceed five years. Makeup contributions or elective deferrals may...

  6. 20 CFR 1002.262 - When is the employer required to make the plan contribution that is attributable to the employee...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... allowed (but not required) to make up his or her missed contributions or elective deferrals. These makeup..., with the repayment period not to exceed five years. Makeup contributions or elective deferrals may...

  7. Addressing Climate Change Adaptation in Regional Transportation Plans in California: A Guide and Online Visualization Tool for Planners to Incorporate Risks of Climate Change Impacts in Policy and Decision-Making

    NASA Astrophysics Data System (ADS)

    Tao, W.; Tucker, K.; DeFlorio, J.

    2012-12-01

    The reality of a changing climate means that transportation and planning agencies need to understand the potential effects of changes in storm activity, sea levels, temperature, and precipitation patterns; and develop strategies to ensure the continuing robustness and resilience of transportation infrastructure and services. This is a relatively new challenge for California's regional planning agencies - adding yet one more consideration to an already complex and multifaceted planning process. In that light, the California Department of Transportation (Caltrans) is developing a strategy framework using a module-based process that planning agencies can undertake to incorporating the risks of climate change impacts into their decision-making and long-range transportation plans. The module-based approach was developed using a best practices survey of existing work nationally, along with a set of structured interviews with metropolitan planning organizations (MPOs) and regional transportation planning agencies (RTPAs) within California. Findings led to the development of a process, as well as a package of foundational geospatial layers (i.e. the Statewide Transportation Asset Geodatabase - STAG), primarily comprising state and Federal transportation assets. These assets are intersected with a set of geospatial layers for the climate stressors of relevance in the state which are placed in the same reference layers as the STAG; thus providing a full set of GIS layers that can be a starting point for MPOs/RTPAs that want to follow the step-by-step module-based approach in its entirety. The fast-paced changes in science and climate change knowledge requires a flexible platform to display continuously evolving information. To this end, the development of the modules are accompanied by a set of geospatial analysis disseminated using an online web portal. In this way, the information can be relayed to MPO/RTPAs in a easy-to-use fashion that can help them follow the modules

  8. An Assessment of Decision-Making Processes: The Feasibility of Incorporating Climate Change Information into Land Protection Planning (External Review Draft)

    EPA Science Inventory

    This report was prepared by the Global Change Research Program (GCRP) in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA). This draft report is a review of decision-making pro...

  9. Assessing Competing Demands and Charting a Course: A Phenomenological Study of Advanced Placement U.S. History Teachers' Decision Making and Course Planning

    ERIC Educational Resources Information Center

    Poole, Kerry D.

    2014-01-01

    Florida has experienced some of the greatest growth of Advanced Placement (AP) programs in recent years and student scores on the AP exams have evolved into a highly significant metric in evaluating student proficiency and teacher and school effectiveness. Despite this growth, it is not well known how AP teachers make decisions about the content…

  10. A Guide to Developing Adult Career Decision-Making Programs and Services. New Hampshire Plans, Career Education 1978-83. Volume 4 of 4 Volumes.

    ERIC Educational Resources Information Center

    New Hampshire State Dept. of Education, Concord.

    Based on eight goals assessed as desired outcomes for a career-educated person, this guide is an outline of how an educational organization or community agency might develop a career decision-making program for adults. Both parts of the guide's purpose--meeting educational needs and meeting community needs--are discussed, including what is…

  11. Clastogenic action of hydroperoxy-5,8,11,13-icosatetraenoic acids on the mouse embryo fibroblasts C3H/10T 1/2

    SciTech Connect

    Ochi, T.; Cerutti, P.A.

    1987-02-01

    Phorbol 12-myristate 13-acetate induces the release of a low molecular weight clastogenic factor from monocytes. Hydroperoxy-5,8,11,13-icosatetraenoic acids represent major components of clastogenic factor. The authors report that several isomeric hydroperoxy-5,8,11,13-icosatetraenoic acids efficiently induce DNA strand breakage and/or alkali-labile sites in the mouse embryo fibroblasts C3H/10T 1/2. Fe chelation by desferrioxamine suppresses breakage indicating the participation of Fe-catalyzed radical reactions. An additional 37% inhibition is observed upon addition of the Ca/sup 2 +/ chelators EGTA and quin-2. This result suggests that hydroxy-peroxy-5,8,11,13-icosatetraenoic acid may activate a Ca/sup 2 +/-dependent nuclease. The addition of the antioxidant enzymes CuZn-superoxide dismutase and catalase had no effect, while glutathione peroxidase suppressed strand breakage by 90%.

  12. [The planned home care transfer by a local medical support hospital and the introduction to home intravenous hyper alimentation--the making of a home care patient's instruction plan document].

    PubMed

    Shinobu, Akiko; Ohtsu, Yoko

    2004-12-01

    It is important to offer continuous medical service without interrupting everyone's various job functions at the Tama Numbu-Chiiki Hospitals in order to secure the quality and safety of home medical care to patients and their families. From 1998 up to the present, home intravenous hyper alimentation (home IVH) has been introduced by individually exchanging information that was based on items such as clinical case, doctor and caregiver in charge of the day, and introductory information. Five years have passed since we started an introduction of home IVH, and it appears that the medical cooperation of home IVH between the Minami-tama medical region and its neighboring area has been established. Then, we arranged an examination of the past 2 years based on the 57 patients who elected to choose home IVH instruction. Consequently, we created "home IVH introduction plan document" in standardizing a flow from home IVH introduction to post-hospital intervention. Since November of 2003, the plan document has been utilized and carried out to 5 patients by the end of February in 2004. This home IVH introduction plan document was able to clarify the role of medical person in connection with the patient. Therefore, we could not only share the information, but also could transfer medical care smoothly from the hospital to the patient's home.

  13. High consistency forming process for paper making. Part 1. A research, development, and demonstration program plan for the US Papermaking Industry. Final report

    SciTech Connect

    Not Available

    1980-04-01

    The subject of research, development, and demonstration (RD and D) of energy conserving technologies applicable to papermaking operations downstream of the pulping process is addressed. An RD and D Program Plan is presented based on a survey of leading representatives of the papermaking industry, equipment manufacturers, consulting engineering firms, the American Paper Institute, and the Technical Association of the Pulp and Paper Industry. For perspective, the program plan is presented against the general background of the industry's current issues and concerns. The second part of the paper, Phase I, final report, deals with papermaking test facilities. The case for a centralized test facility is discussed. The results of a survey of existing pilot paper machines are presented. The energy saving potential of high consistency forming is considered and related to existing evidence. Simple theoretical models for the press nip action and the drying process are developed to predict where high consistency forming will reduce energy consumption. A special dynamic former has been designed, fabricated, and commissioned to allow development of a laboratory high consistency headbox. The design and construction of a low speed headbox has been completed and the complete system operated. Special equipment and techniques for the measurement of the water and air permeability of sheet samples have been developed and are described.

  14. Construction of a technique plan repository and evaluation system based on AHP group decision-making for emergency treatment and disposal in chemical pollution accidents.

    PubMed

    Shi, Shenggang; Cao, Jingcan; Feng, Li; Liang, Wenyan; Zhang, Liqiu

    2014-07-15

    The environmental pollution resulting from chemical accidents has caused increasingly serious concerns. Therefore, it is very important to be able to determine in advance the appropriate emergency treatment and disposal technology for different types of chemical accidents. However, the formulation of an emergency plan for chemical pollution accidents is considerably difficult due to the substantial uncertainty and complexity of such accidents. This paper explains how the event tree method was used to create 54 different scenarios for chemical pollution accidents, based on the polluted medium, dangerous characteristics and properties of chemicals involved. For each type of chemical accident, feasible emergency treatment and disposal technology schemes were established, considering the areas of pollution source control, pollutant non-proliferation, contaminant elimination and waste disposal. Meanwhile, in order to obtain the optimum emergency disposal technology schemes as soon as the chemical pollution accident occurs from the plan repository, the technique evaluation index system was developed based on group decision-improved analytical hierarchy process (AHP), and has been tested by using a sudden aniline pollution accident that occurred in a river in December 2012. PMID:24887122

  15. Construction of a technique plan repository and evaluation system based on AHP group decision-making for emergency treatment and disposal in chemical pollution accidents.

    PubMed

    Shi, Shenggang; Cao, Jingcan; Feng, Li; Liang, Wenyan; Zhang, Liqiu

    2014-07-15

    The environmental pollution resulting from chemical accidents has caused increasingly serious concerns. Therefore, it is very important to be able to determine in advance the appropriate emergency treatment and disposal technology for different types of chemical accidents. However, the formulation of an emergency plan for chemical pollution accidents is considerably difficult due to the substantial uncertainty and complexity of such accidents. This paper explains how the event tree method was used to create 54 different scenarios for chemical pollution accidents, based on the polluted medium, dangerous characteristics and properties of chemicals involved. For each type of chemical accident, feasible emergency treatment and disposal technology schemes were established, considering the areas of pollution source control, pollutant non-proliferation, contaminant elimination and waste disposal. Meanwhile, in order to obtain the optimum emergency disposal technology schemes as soon as the chemical pollution accident occurs from the plan repository, the technique evaluation index system was developed based on group decision-improved analytical hierarchy process (AHP), and has been tested by using a sudden aniline pollution accident that occurred in a river in December 2012.

  16. Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8.

    PubMed

    Leclère, Lucas; Bause, Markus; Sinigaglia, Chiara; Steger, Julia; Rentzsch, Fabian

    2016-05-15

    The development of the oral pole in cnidarians and the posterior pole in bilaterians is regulated by canonical Wnt signaling, whereas a set of transcription factors, including Six3/6 and FoxQ2, controls aboral development in cnidarians and anterior identity in bilaterians. However, it is poorly understood how these two patterning systems are initially set up in order to generate correct patterning along the primary body axis. Investigating the early steps of aboral pole formation in the sea anemone Nematostella vectensis, we found that, at blastula stage, oral genes are expressed before aboral genes and that Nvβ-catenin regulates both oral and aboral development. In the oral hemisphere, Nvβ-catenin specifies all subdomains except the oral-most, NvSnailA-expressing domain, which is expanded upon Nvβ-catenin knockdown. In addition, Nvβ-catenin establishes the aboral patterning system by promoting the expression of NvSix3/6 at the aboral pole and suppressing the Wnt receptor NvFrizzled5/8 at the oral pole. NvFrizzled5/8 expression thereby gets restricted to the aboral domain. At gastrula stage, NvSix3/6 and NvFrizzled5/8 are both expressed in the aboral domain, but they have opposing activities, with NvSix3/6 maintaining and NvFrizzled5/8 restricting the size of the aboral domain. At planula stage, NvFrizzled5/8 is required for patterning within the aboral domain and for regulating the size of the apical organ by modulation of a previously characterized FGF feedback loop. Our findings suggest conserved roles for Six3/6 and Frizzled5/8 in aboral/anterior development and reveal key functions for Nvβ-catenin in the patterning of the entire oral-aboral axis of Nematostella. PMID:26989171

  17. Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8

    PubMed Central

    Leclère, Lucas; Bause, Markus; Sinigaglia, Chiara; Steger, Julia; Rentzsch, Fabian

    2016-01-01

    ABSTRACT The development of the oral pole in cnidarians and the posterior pole in bilaterians is regulated by canonical Wnt signaling, whereas a set of transcription factors, including Six3/6 and FoxQ2, controls aboral development in cnidarians and anterior identity in bilaterians. However, it is poorly understood how these two patterning systems are initially set up in order to generate correct patterning along the primary body axis. Investigating the early steps of aboral pole formation in the sea anemone Nematostella vectensis, we found that, at blastula stage, oral genes are expressed before aboral genes and that Nvβ-catenin regulates both oral and aboral development. In the oral hemisphere, Nvβ-catenin specifies all subdomains except the oral-most, NvSnailA-expressing domain, which is expanded upon Nvβ-catenin knockdown. In addition, Nvβ-catenin establishes the aboral patterning system by promoting the expression of NvSix3/6 at the aboral pole and suppressing the Wnt receptor NvFrizzled5/8 at the oral pole. NvFrizzled5/8 expression thereby gets restricted to the aboral domain. At gastrula stage, NvSix3/6 and NvFrizzled5/8 are both expressed in the aboral domain, but they have opposing activities, with NvSix3/6 maintaining and NvFrizzled5/8 restricting the size of the aboral domain. At planula stage, NvFrizzled5/8 is required for patterning within the aboral domain and for regulating the size of the apical organ by modulation of a previously characterized FGF feedback loop. Our findings suggest conserved roles for Six3/6 and Frizzled5/8 in aboral/anterior development and reveal key functions for Nvβ-catenin in the patterning of the entire oral-aboral axis of Nematostella. PMID:26989171

  18. On the recent seismic activity in North-Eastern Aegean Sea including the Mw5.8 earthquake on 8 January 2013

    PubMed Central

    SARLIS, Nicholas V.

    2013-01-01

    In the last week of November 2012, we announced that a strong electrotelluric disturbance, which we judged to be a Seismic Electric Signal (SES) activity, was recorded at station Assiros located in Northern Greece. This disturbance was actually followed by an Mw5.8 earthquake on 8 January 2013 in North-Eastern Aegean Sea. Here we show that, by analyzing this SES activity and employing the natural time analysis of subsequent seismicity, we estimated the epicentral location, magnitude and occurrence time which are reasonably compatible with those of the Mw5.8 event. PMID:24213207

  19. My Reproductive Life Plan

    MedlinePlus

    ... Information For... Media Policy Makers My Reproductive Life Plan Language: English Español (Spanish) Recommend on Facebook Tweet ... use with their patients. How to Make a Plan First, think about your goals for school, for ...

  20. Managing wetlands for waterbirds: How managers can make a difference in improving habitat to support a North American Bird Conservation Plan

    USGS Publications Warehouse

    Erwin, R.M.; Laubhan, M.K.; Cornely, J.E.; Bradshaw, D.M.; Bonney, Rick; Pashley, David N.; Cooper, Robert; Niles, Larry

    2000-01-01

    Wetlands are the most productive ecosystems in the world, yet they have suffered more loss and degradation than any other ecosystem. Not surprisingly, 50% (29 of 58) of all the bird species in the U. S. (excluding Hawaii and territories) that are listed either as federally threatened or endangered, or are on the U. S. Fish & Wildlife Service 1995 List of Migratory Nongame Birds of Management Concern, occupy wetland or aquatic habitats even though many remaining wetlands across the North American landscape already are managed primarily for waterbirds. Some of these wetlands are administered by federal and state entities (e.g., national wildlife refuges, national and state parks, state wetland management areas) or are maintained on private lands through federally supported restoration and enhancement programs (e.g., Conservation Reserve Program, Wetland Reserve Program, Waterfowl Production Areas, and Partners for Wildlife). Private organizations, such as the National Audubon Society, The Nature Conservancy, and private hunting clubs, also own wetland areas that are managed specifically to benefit wildlife. If management philosophies are altered to consider the entire complex of wetlands, many wetlands can provide benefits to a broad array of waterbirds, as opposed to just one or a few species. However, challenges for natural resource managers are in forming partnerships with owners-managers of wetlands where the objectives are not primarily wildlife oriented. These owners or managers need to be included in wetland training workshops in an attempt to educate them about wetland values and secondary wildlife benefits that may be derived in flooded agricultural lands, aquaculture ponds, altered coastal marshes (mosquito control), and salt evaporation ponds. In some cases, compensation for crop damages by wildlife may be a necessary part of any cooperative agreements. In the development of a North American Bird Conservation Plan we propose a four-step approach and

  1. The Mw 5.8 Mineral, Virginia, earthquake of August 2011 and aftershock sequence: constraints on earthquake source parameters and fault geometry

    USGS Publications Warehouse

    McNamara, Daniel E.; Benz, H.M.; Herrmann, Robert B.; Bergman, Eric A.; Earle, Paul; Meltzer, Anne; Withers, Mitch; Chapman, Martin

    2014-01-01

    The Mw 5.8 earthquake of 23 August 2011 (17:51:04 UTC) (moment, M0 5.7×1017  N·m) occurred near Mineral, Virginia, within the central Virginia seismic zone and was felt by more people than any other earthquake in United States history. The U.S. Geological Survey (USGS) received 148,638 felt reports from 31 states and 4 Canadian provinces. The USGS PAGER system estimates as many as 120,000 people were exposed to shaking intensity levels of IV and greater, with approximately 10,000 exposed to shaking as high as intensity VIII. Both regional and teleseismic moment tensor solutions characterize the earthquake as a northeast‐striking reverse fault that nucleated at a depth of approximately 7±2  km. The distribution of reported macroseismic intensities is roughly ten times the area of a similarly sized earthquake in the western United States (Horton and Williams, 2012). Near‐source and far‐field damage reports, which extend as far away as Washington, D.C., (135 km away) and Baltimore, Maryland, (200 km away) are consistent with an earthquake of this size and depth in the eastern United States (EUS). Within the first few days following the earthquake, several government and academic institutions installed 36 portable seismograph stations in the epicentral region, making this among the best‐recorded aftershock sequences in the EUS. Based on modeling of these data, we provide a detailed description of the source parameters of the mainshock and analysis of the subsequent aftershock sequence for defining the fault geometry, area of rupture, and observations of the aftershock sequence magnitude–frequency and temporal distribution. The observed slope of the magnitude–frequency curve or b‐value for the aftershock sequence is consistent with previous EUS studies (b=0.75), suggesting that most of the accumulated strain was released by the mainshock. The aftershocks define a rupture that extends between approximately 2–8 km in depth and 8–10 km along

  2. A National Study: the Effect of Egyptian Married Women's Decision-Making Autonomy on the use of Modern Family Planning Methods.

    PubMed

    AlSumri, Hana H

    2015-12-01

    Contraceptive use is vital in protecting the health of women and the survival of their children. This study aims to test whether women's autonomy influences their use of modern contraception methods and to determine the mediating effect of education and employment. A cross sectional study using Egypt's 2008 demographic and health survey was carried out including a sample of 13,734 married women aged 15-49 years. Women's decision-making autonomy score was obtained from 5 questions on who has the final say on various household decisions. Household decision-making autonomy was significantly associated with current modern contraceptive use. Women with intermediate and high autonomy were 1.19 (95%CI 1.04-1.35) and 1.32 (95% CI 1.18-1.49) more likely to use modern contraception methods compared to women with low autonomy. Women's education and employment did not mediate this relation. This study supports the evidence of the positive role of women's autonomy on their uptake of contraceptive methods and this is an independent role and not explained by their educational or employment status.

  3. A National Study: the Effect of Egyptian Married Women's Decision-Making Autonomy on the use of Modern Family Planning Methods.

    PubMed

    AlSumri, Hana H

    2015-12-01

    Contraceptive use is vital in protecting the health of women and the survival of their children. This study aims to test whether women's autonomy influences their use of modern contraception methods and to determine the mediating effect of education and employment. A cross sectional study using Egypt's 2008 demographic and health survey was carried out including a sample of 13,734 married women aged 15-49 years. Women's decision-making autonomy score was obtained from 5 questions on who has the final say on various household decisions. Household decision-making autonomy was significantly associated with current modern contraceptive use. Women with intermediate and high autonomy were 1.19 (95%CI 1.04-1.35) and 1.32 (95% CI 1.18-1.49) more likely to use modern contraception methods compared to women with low autonomy. Women's education and employment did not mediate this relation. This study supports the evidence of the positive role of women's autonomy on their uptake of contraceptive methods and this is an independent role and not explained by their educational or employment status. PMID:27337855

  4. The Teacher's Ongoing Role in Creating a Developmentally Appropriate Early Childhood Program: A Self-Study Process for Teachers of Children Ages 5-8.

    ERIC Educational Resources Information Center

    Connecticut State Dept. of Education, Hartford.

    This self-study instrument is designed to support teachers' efforts to implement an early childhood program for children of 5-8 years of age that reflects the qualities of developmentally appropriate programming described in Connecticut's Guide to Program Development for Kindergarten (1988). The contents, which are presented in checklist format,…

  5. National Association for Research in Science Teaching Annual Meeting, Abstracts of Presented Papers (55th, Lake Geneva, Wisconsin, April 5-8, 1982).

    ERIC Educational Resources Information Center

    White, Arthur L., Ed.; Blosser, Patricia E., Ed.

    Abstracts of most of the papers presented at the 55th annual meeting of the National Association for Research in Science Teaching (NARST), held at the Abbey, Lake Geneva, WI, April 5-8, 1982 have been collected in this publication. Papers relate to such topics as teacher education: preservice and inservice, cognitive development, research…

  6. The New Nation's Westward Expansion. Grade 5 Model Lesson for Standard 5.8. California History-Social Science Course Models.

    ERIC Educational Resources Information Center

    Zachlod, Michelle, Ed.

    California State Standard 5.8 is delineated in the following way: "Students trace the colonization, immigration, and settlement patterns of the American people from 1789 to the mid-1800s, with emphasis on the role of economic incentives, effects of the physical and political geography, and transportation systems." Students answer six questions…

  7. Mathematics Curriculum Changes in Republic of Serbia for Grades 5-8 After the Break-Up of Socialist Federal Republic of Yugoslavia

    ERIC Educational Resources Information Center

    Vlajic, Jovana

    2011-01-01

    The purpose of this study was to determine the changes in the mathematics curriculum for grades 5-8 in the Republic of Serbia after the break-up of SFRY. In particular, the research sought to identify the changes in the mathematics curriculum in terms of curriculum content and learning objectives, textbooks, and high school entrance examination…

  8. A universal model for the secondary structure of 5.8S ribosomal RNA molecules, their contact sites with 28S ribosomal RNAs, and their prokaryotic equivalent.

    PubMed Central

    Vaughn, J C; Sperbeck, S J; Ramsey, W J; Lawrence, C B

    1984-01-01

    The phylogenetic approach (ref. 1) has been utilized in construction of a universal 5.8S rRNA secondary structure model, in which about 65% of the residues exist in paired structures. Conserved nucleotides primarily occupy unpaired regions. Multiple compensating base changes are demonstrated to be present in each of the five postulated helices, thereby forming a major basis for their proof. The results of chemical and enzymatic probing of 5.8S rRNAs (ref. 13, 32) are fully consistent with, and support, our model. This model differs in several ways from recently proposed 5.8S rRNA models (ref. 3, 4), which are discussed. Each of the helices in our model has been extended to the corresponding bacterial, chloroplast and mitochondrial sequences, which are demonstrated to be positionally conserved by alignment with their eukaryotic counterparts. This extension is also made for the base paired 5.8S/28S contact points, and their prokaryotic and organelle counterparts. The demonstrated identity of secondary structure in these diverse molecules strongly suggests that they perform equivalent functions in prokaryotic and eukaryotic ribosomes. PMID:6208532

  9. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies

    SciTech Connect

    Jackman, A.L.; Alison, D.L.; Calvert, A.H.; Harrap, K.R.

    1986-06-01

    The properties are described of a mutant L1210 cell line (L1210:C15) with acquired resistance (greater than 200-fold) to the thymidylate synthase (TS) inhibitor N10-propargyl-5,8-dideazafolic acid. TS was overproduced 45-fold and was accompanied by a small increase in the activity of dihydrofolate reductase (2.6-fold). Both the level of resistance and enzyme activities were maintained in drug-free medium (greater than 300 generations). Failure of N10-propargyl-5,8-dideazafolic acid to suppress the (/sup 3/H)-2'-deoxyuridine incorporation into the acid-precipitable material of the resistant line supported the evidence that TS overproduction was the mechanism of resistance; consequently the L1210:C15 cells were largely cross-resistant to another (but weaker) TS inhibitor, 5,8-dideazafolic acid. Minimal cross-resistance was observed to the dihydrofolate reductase inhibitors methotrexate and 5-methyl-5,8-dideazaaminopterin (5- and 2-fold, respectively). L1210 and L1210:C15 cells were, however, equally sensitive to 5-fluorodeoxyuridine (FdUrd), an unexpected finding since a metabolite, 5-fluorodeoxyuridine monophosphate, is a potent TS inhibitor; however, this cytotoxicity against the L1210:C15 cells was antagonized by coincubation with 5 microM folinic acid although folinic acid potentiated the cytotoxicity of FdUrd to the N10-propargyl-5,8-dideazafolic acid-sensitive L1210 line. Thymidine was much less effective as a FdUrd protecting agent in the L1210:C15 when compared with the L1210 cells; however, a combination of thymidine plus hypoxanthine was without any additional effect (compared with thymidine alone) against the sensitive line but effectively protected L1210:C15 cells.

  10. Physical, morphological and functional differences between ph 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide Abeta.

    PubMed

    Wood, S J; Maleeff, B; Hart, T; Wetzel, R

    1996-03-15

    The Alzheimer's amyloid peptide Abeta(1-40) generates a turbid, Congo re-binding aggregation reaction product within minutes when incubated in the pH range 5 to 6. At pH 7.4, Abeta forms little or no aggregate in this time frame, requiring hours or days, rather than minutes, to complete fibril formation. The pH 5.8 aggregates are not amyloid fibrils, but rather appear in electron micrographs as a mixture of larger particles of different morphologies. These aggregates differ from classical fibrils by a number of other measures. Per mass of peptide aggregated, the pH 5.8 product binds less Congo red and thioflavin T than does aggregate grow in unstirred reactions at pH 7.4. Both the pH 5.8 and 7.4 aggregates exhibit light scattering at 90 degrees. However, while the pH 5.8 aggregate is visible in suspension by the light microscopy, and exhibits turbidity at 405 nm, the fibrils grown at pH 7.4 in an unstirred reaction are transparent. The two aggregate types do not interconvert in pH shift experiments. Most dramatically, and in contrast to fibrils grown at pH 7.4, the turbid aggregate generated at pH 5.8 is incapable of seeding fibril growth at pH 7.4. Although proteolytic processing of betaAPP to generate Abeta probably takes place in a low pH compartment of the cell, our results suggest that fibril formation is not likely to be initiated in such an environment.

  11. Pax2/5/8 and Pax6 alternative splicing events in basal chordates and vertebrates: a focus on paired box domain

    PubMed Central

    Fabian, Peter; Kozmikova, Iryna; Kozmik, Zbynek; Pantzartzi, Chrysoula N.

    2015-01-01

    Paired box transcription factors play important role in development and tissue morphogenesis. The number of Pax homologs varies among species studied so far, due to genome and gene duplications that have affected PAX family to a great extent. Based on sequence similarity and functional domains, four Pax classes have been identified in chordates, namely Pax1/9, Pax2/5/8, Pax3/7, and Pax4/6. Numerous splicing events have been reported mainly for Pax2/5/8 and Pax6 genes. Of significant interest are those events that lead to Pax proteins with presumed novel properties, such as altered DNA-binding or transcriptional activity. In the current study, a thorough analysis of Pax2/5/8 splicing events from cephalochordates and vertebrates was performed. We focused more on Pax2/5/8 and Pax6 splicing events in which the paired domain is involved. Three new splicing events were identified in Oryzias latipes, one of which seems to be conserved in Acanthomorphata. Using representatives from deuterostome and protostome phyla, a comparative analysis of the Pax6 exon-intron structure of the paired domain was performed, during an attempt to estimate the time of appearance of the Pax6(5a) mRNA isoform. As shown in our analysis, this splicing event is characteristic of Gnathostomata and is absent in the other chordate subphyla. Moreover, expression pattern of alternative spliced variants was compared between cephalochordates and fish species. In summary, our data indicate expansion of alternative mRNA variants in paired box region of Pax2/5/8 and Pax6 genes during the course of vertebrate evolution. PMID:26191073

  12. The role of responsible gambling strategy and gambling passion in the online gamblers' decision-making process: revising the theory of planned behavior.

    PubMed

    Lee, Jaeseok; Chen, Chih-Chien; Song, Hak-Jun; Lee, Choong-Ki

    2014-06-01

    This study revised the theory of planned behavior (TPB) by incorporating the new concepts of gambling passion and responsible gambling strategy (RGS) to predict gamblers' intention to gamble in online sports betting. The data were collected at the end of March in 2012 through an online gambling website. The findings indicated that the inclusion of two types of gambling passion and two types of RGS explains online gambling intention well. Specifically, out of the original antecedent predictors of TPB, attitude toward online gambling was positively related to harmonious passion. Subjective norm had a positive relationship with both harmonious and obsessive passion. The results also showed that perceived behavioral control does not have a significant effect on the two gambling passions but has a direct and significant influence on behavioral intention. Additionally, the compulsory RGS had a negative effect on obsessive passion, whereas supplementary RGS had concurrent positive impacts on harmonious and obsessive passion. Lastly, the two gambling passions were notable predictors of behavioral intention toward online sports betting. PMID:23334577

  13. What to include in your birth plan

    MedlinePlus

    Pregnancy - birth plan ... Birth plans are guides that parents-to-be make to help their health care providers best support ... of things to consider before you make a birth plan. This is a great time to learn ...

  14. Understanding Perceptions of Climate Change, Priorities, and Decision-Making among Municipalities in Lima, Peru to Better Inform Adaptation and Mitigation Planning.

    PubMed

    Siña, Mariella; Wood, Rachel C; Saldarriaga, Enrique; Lawler, Joshua; Zunt, Joseph; Garcia, Patricia; Cárcamo, César

    2016-01-01

    Climate change poses multiple risks to the population of Lima, the largest city and capital of Peru, located on the Pacific coast in a desert ecosystem. These risks include increased water scarcity, increased heat, and the introduction and emergence of vector-borne and other climate sensitive diseases. To respond to these threats, it is necessary for the government, at every level, to adopt more mitigation and adaptation strategies. Here, focus groups were conducted with representatives from five Lima municipalities to determine priorities, perception of climate change, and decision-making processes for implementing projects within each municipality. These factors can affect the ability and desire of a community to implement climate change adaptation and mitigation strategies. The results show that climate change and other environmental factors are of relatively low priority, whereas public safety and water and sanitation services are of highest concern. Perhaps most importantly, climate change is not well understood among the municipalities. Participants had trouble distinguishing climate change from other environmental issues and did not fully understand its causes and effects. Greater understanding of what climate change is and why it is important is necessary for it to become a priority for the municipalities. Different aspects of increased climate change awareness seem to be connected to having experienced extreme weather events, whether related or not to climate change, and to higher socioeconomic status. PMID:26808087

  15. Understanding Perceptions of Climate Change, Priorities, and Decision-Making among Municipalities in Lima, Peru to Better Inform Adaptation and Mitigation Planning

    PubMed Central

    Saldarriaga, Enrique; Lawler, Joshua; Zunt, Joseph; Garcia, Patricia; Cárcamo, César

    2016-01-01

    Climate change poses multiple risks to the population of Lima, the largest city and capital of Peru, located on the Pacific coast in a desert ecosystem. These risks include increased water scarcity, increased heat, and the introduction and emergence of vector-borne and other climate sensitive diseases. To respond to these threats, it is necessary for the government, at every level, to adopt more mitigation and adaptation strategies. Here, focus groups were conducted with representatives from five Lima municipalities to determine priorities, perception of climate change, and decision-making processes for implementing projects within each municipality. These factors can affect the ability and desire of a community to implement climate change adaptation and mitigation strategies. The results show that climate change and other environmental factors are of relatively low priority, whereas public safety and water and sanitation services are of highest concern. Perhaps most importantly, climate change is not well understood among the municipalities. Participants had trouble distinguishing climate change from other environmental issues and did not fully understand its causes and effects. Greater understanding of what climate change is and why it is important is necessary for it to become a priority for the municipalities. Different aspects of increased climate change awareness seem to be connected to having experienced extreme weather events, whether related or not to climate change, and to higher socioeconomic status. PMID:26808087

  16. Understanding Perceptions of Climate Change, Priorities, and Decision-Making among Municipalities in Lima, Peru to Better Inform Adaptation and Mitigation Planning.

    PubMed

    Siña, Mariella; Wood, Rachel C; Saldarriaga, Enrique; Lawler, Joshua; Zunt, Joseph; Garcia, Patricia; Cárcamo, César

    2016-01-01

    Climate change poses multiple risks to the population of Lima, the largest city and capital of Peru, located on the Pacific coast in a desert ecosystem. These risks include increased water scarcity, increased heat, and the introduction and emergence of vector-borne and other climate sensitive diseases. To respond to these threats, it is necessary for the government, at every level, to adopt more mitigation and adaptation strategies. Here, focus groups were conducted with representatives from five Lima municipalities to determine priorities, perception of climate change, and decision-making processes for implementing projects within each municipality. These factors can affect the ability and desire of a community to implement climate change adaptation and mitigation strategies. The results show that climate change and other environmental factors are of relatively low priority, whereas public safety and water and sanitation services are of highest concern. Perhaps most importantly, climate change is not well understood among the municipalities. Participants had trouble distinguishing climate change from other environmental issues and did not fully understand its causes and effects. Greater understanding of what climate change is and why it is important is necessary for it to become a priority for the municipalities. Different aspects of increased climate change awareness seem to be connected to having experienced extreme weather events, whether related or not to climate change, and to higher socioeconomic status.

  17. Coastal Adaptation Planning for Sea Level Rise and Extremes: A Global Model for Adaptation Decision-making at the Local Level Given Uncertain Climate Projections

    NASA Astrophysics Data System (ADS)

    Turner, D.

    2014-12-01

    Understanding the potential economic and physical impacts of climate change on coastal resources involves evaluating a number of distinct adaptive responses. This paper presents a tool for such analysis, a spatially-disaggregated optimization model for adaptation to sea level rise (SLR) and storm surge, the Coastal Impact and Adaptation Model (CIAM). This decision-making framework fills a gap between very detailed studies of specific locations and overly aggregate global analyses. While CIAM is global in scope, the optimal adaptation strategy is determined at the local level, evaluating over 12,000 coastal segments as described in the DIVA database (Vafeidis et al. 2006). The decision to pursue a given adaptation measure depends on local socioeconomic factors like income, population, and land values and how they develop over time, relative to the magnitude of potential coastal impacts, based on geophysical attributes like inundation zones and storm surge. For example, the model's decision to protect or retreat considers the costs of constructing and maintaining coastal defenses versus those of relocating people and capital to minimize damages from land inundation and coastal storms. Uncertain storm surge events are modeled with a generalized extreme value distribution calibrated to data on local surge extremes. Adaptation is optimized for the near-term outlook, in an "act then learn then act" framework that is repeated over the model time horizon. This framework allows the adaptation strategy to be flexibly updated, reflecting the process of iterative risk management. CIAM provides new estimates of the economic costs of SLR; moreover, these detailed results can be compactly represented in a set of adaptation and damage functions for use in integrated assessment models. Alongside the optimal result, CIAM evaluates suboptimal cases and finds that global costs could increase by an order of magnitude, illustrating the importance of adaptive capacity and coastal policy.

  18. Detection and identification of fungal pathogens by PCR and by ITS2 and 5.8S ribosomal DNA typing in ocular infections.

    PubMed

    Ferrer, C; Colom, F; Frasés, S; Mulet, E; Abad, J L; Alió, J L

    2001-08-01

    The goal of this study was to determine whether sequence analysis of internal transcribed spacer/5.8S ribosomal DNA (rDNA) can be used to detect fungal pathogens in patients with ocular infections (endophthalmitis and keratitis). Internal transcribed spacer 1 (ITS1) and ITS2 and 5.8S rDNA were amplified by PCR and seminested PCR to detect fungal DNA. Fifty strains of 12 fungal species (yeasts and molds) were used to test the selected primers and conditions of the PCR. PCR and seminested PCR of this region were carried out to evaluate the sensitivity and specificity of the method. It proved possible to amplify the ITS2/5.8S region of all the fungal strains by this PCR method. All negative controls (human and bacterial DNA) were PCR negative. The sensitivity of the seminested PCR amplification reaction by DNA dilutions was 1 organism per PCR, and the sensitivity by cell dilutions was fewer than 10 organisms per PCR. Intraocular sampling or corneal scraping was undertaken for all patients with suspected infectious endophthalmitis or keratitis (nonherpetic), respectively, between November 1999 and February 2001. PCRs were subsequently performed with 11 ocular samples. The amplified DNA was sequenced, and aligned against sequences in GenBank at the National Institutes of Health. The results were PCR positive for fungal primers for three corneal scrapings, one aqueous sample, and one vitreous sample; one of them was negative by culture. Molecular fungal identification was successful in all cases. Bacterial detection by PCR was positive for three aqueous samples and one vitreous sample; one of these was negative by culture. Amplification of ITS2/5.8S rDNA and molecular typing shows potential as a rapid technique for identifying fungi in ocular samples.

  19. Detection and Identification of Fungal Pathogens by PCR and by ITS2 and 5.8S Ribosomal DNA Typing in Ocular Infections

    PubMed Central

    Ferrer, Consuelo; Colom, Francisca; Frasés, Susana; Mulet, Emilia; Abad, José L.; Alió, Jorge L.

    2001-01-01

    The goal of this study was to determine whether sequence analysis of internal transcribed spacer/5.8S ribosomal DNA (rDNA) can be used to detect fungal pathogens in patients with ocular infections (endophthalmitis and keratitis). Internal transcribed spacer 1 (ITS1) and ITS2 and 5.8S rDNA were amplified by PCR and seminested PCR to detect fungal DNA. Fifty strains of 12 fungal species (yeasts and molds) were used to test the selected primers and conditions of the PCR. PCR and seminested PCR of this region were carried out to evaluate the sensitivity and specificity of the method. It proved possible to amplify the ITS2/5.8S region of all the fungal strains by this PCR method. All negative controls (human and bacterial DNA) were PCR negative. The sensitivity of the seminested PCR amplification reaction by DNA dilutions was 1 organism per PCR, and the sensitivity by cell dilutions was fewer than 10 organisms per PCR. Intraocular sampling or corneal scraping was undertaken for all patients with suspected infectious endophthalmitis or keratitis (nonherpetic), respectively, between November 1999 and February 2001. PCRs were subsequently performed with 11 ocular samples. The amplified DNA was sequenced, and aligned against sequences in GenBank at the National Institutes of Health. The results were PCR positive for fungal primers for three corneal scrapings, one aqueous sample, and one vitreous sample; one of them was negative by culture. Molecular fungal identification was successful in all cases. Bacterial detection by PCR was positive for three aqueous samples and one vitreous sample; one of these was negative by culture. Amplification of ITS2/5.8S rDNA and molecular typing shows potential as a rapid technique for identifying fungi in ocular samples. PMID:11474006

  20. Clastogenic action of hydroperoxy-5,8,11,13-icosatetraenoic acids on the mouse embryo fibroblasts C3H/10T1/2.

    PubMed Central

    Ochi, T; Cerutti, P A

    1987-01-01

    Phorbol 12-myristate 13-acetate induces the release of a low molecular weight clastogenic factor from monocytes. Hydroperoxy-5,8,11,13-icosatetraenoic acids represent major components of clastogenic factor. We report that several isomeric hydroperoxy-5,8,11,13-icosatetraenoic acids efficiently induce DNA strand breakage and/or alkali-labile sites in the mouse embryo fibroblasts C3H/10T1/2. Fe chelation by desferrioxamine suppresses breakage by approximately equal to 42% indicating the participation of Fe-catalyzed radical reactions. An additional 37% inhibition is observed upon addition of the Ca2+ chelators EGTA and quin-2. This result suggests that hydroxyperoxy-5,8,11,13-icosatetraenoic acid may activate a Ca2+-dependent nuclease. The addition of the antioxidant enzymes CuZn-superoxide dismutase and catalase had no effect, while glutathione peroxidase suppressed strand breakage by 90%. To our knowledge, our results yield a first insight into the mechanism of action of monocyte clastogenic factor and the role of inflammation in tumor promotion. PMID:3469656

  1. Association between the -794 (CATT)5-8  MIF gene polymorphism and susceptibility to acute coronary syndrome in a western Mexican population.

    PubMed

    Valdés-Alvarado, Emmanuel; Muñoz-Valle, José Francisco; Valle, Yeminia; Sandoval-Pinto, Elena; García-González, Ilian Janet; Valdez-Haro, Angélica; De la Cruz-Mosso, Ulises; Flores-Salinas, Héctor Enrique; Padilla-Gutiérrez, Jorgé Ramón

    2014-01-01

    The macrophage migration inhibitory factor (MIF) is related to the progression of atherosclerosis, which, in turn, is a key factor in the development of acute coronary syndrome (ACS). MIF has a CATT short tandem repeat (STR) at position -794 that might be involved in its expression rate. The aim of this study was to investigate the association between the -794 (CATT)5-8  MIF gene polymorphism and susceptibility to ACS in a western Mexican population. This research included 200 ACS patients classified according to the criteria of the American College of Cardiology (ACC) and 200 healthy subjects (HS). The -794 (CATT)5-8  MIF gene polymorphism was analyzed using a conventional polymerase chain reaction (PCR) technique. The 6 allele was the most frequent in both groups (ACS: 54% and HS: 57%). The most common genotypes in ACS patients and HS were 6/7 and 6/6, respectively, and a significant association was found between the 6/7 genotype and susceptibility to ACS (68% versus 47% in ACS and HS, resp., P = 0.03). We conclude that the 6/7 genotype of the MIF -794 (CATT)5-8 polymorphism is associated with susceptibility to ACS in a western Mexican population.

  2. Results of wrist extension reconstruction in C5-8 brachial plexus palsy by transferring the pronator quadratus motor branch to the extensor carpi radialis brevis muscle.

    PubMed

    Bertelli, Jayme Augusto; Ghizoni, Marcos Flávio; Tacca, Cristiano Paulo

    2016-05-01

    OBJECT The objective of this study was to report the results of pronator quadratus (PQ) motor branch transfers to the extensor carpi radialis brevis (ECRB) motor branch to reconstruct wrist extension in C5-8 root lesions of the brachial plexus. METHODS Twenty-eight patients, averaging 24 years of age, with C5-8 root injuries underwent operations an average of 7 months after their accident. In 19 patients, wrist extension was impossible at baseline, whereas in 9 patients wrist extension was managed by activating thumb and wrist extensors. When these 9 patients grasped an object, their wrist dropped and grasp strength was lost. Wrist extension was reconstructed by transferring the PQ motor to the ECRB motor branch. After surgery, patients were followed for at least 12 months, with final follow-up an average of 22 months after surgery. RESULTS Successful reinnervation of the ECRB was demonstrated in 27 of the 28 patients. In 25 of the patients, wrist extension scored M4, and in 2 it scored M3. CONCLUSIONS In C5-8 root injuries, wrist extension can be predictably reconstructed by transferring the PQ motor branch to reinnervate the ECRB.

  3. The 2011 Mineral, VA M5.8 Earthquake Ground Motions and Stress Drop: An Important Contribution to the NGA East Ground Motion Database

    NASA Astrophysics Data System (ADS)

    Cramer, C. H.; Kutliroff, J.; Dangkua, D.

    2011-12-01

    The M5.8 Mineral, Virginia earthquake of August 23, 2011 is the largest instrumentally recorded earthquake in eastern North America since the 1988 M5.9 Saguenay, Canada earthquake. Historically, a similar magnitude earthquake occurred on May 31, 1897 at 18:58 UCT in western Virginia west of Roanoke. Paleoseismic evidence for larger magnitude earthquakes has also been found in the central Virginia region. The Next Generation Attenuation (NGA) East project to develop new ground motion prediction equations for stable continental regions (SCRs), including eastern North America (ENA), is ongoing at the Pacific Earthquake Engineering Research Center funded by the U.S. Nuclear Regulatory Commission, the U.S. Geological Survey, the Electric Power Research Institute, and the U.S. Department of Energy. The available recordings from the M5.8 Virginia are being added to the NGA East ground motion database. Close in (less than 100 km) strong motion recordings are particularly interesting for both ground motion and stress drop estimates as most close-in broadband seismometers clipped on the mainshock. A preliminary estimate for earthquake corner frequency for the M5.8 Virginia earthquake of ~0.7 Hz has been obtained from a strong motion record 57 km from the mainshock epicenter. For a M5.8 earthquake this suggests a Brune stress drop of ~300 bars for the Virginia event. Very preliminary comparisons using accelerometer data suggest the ground motions from the M5.8 Virginia earthquake agree well with current ENA ground motion prediction equations (GMPEs) at short periods (PGA, 0.2 s) and are below the GMPEs at longer periods (1.0 s), which is the same relationship seen from other recent M5 ENA earthquakes. We will present observed versus GMPE ground motion comparisons for all the ground motion observations and stress drop estimates from strong motion recordings at distances less than 100 km. A review of the completed NGA East ENA ground motion database will also be provided.

  4. Making Pickles

    ERIC Educational Resources Information Center

    Klein, Sarah

    1977-01-01

    Making pickles developed from a laboratory lesson during a unit on solutions, suspensions, acids, and bases. The pickle lab has been used as a summation and application of these topics. Directions for setting up the lab experience and actually making the pickles are included. (MA)

  5. Making Math and Making Dance: A Closer Look at Integration

    ERIC Educational Resources Information Center

    Rosenfeld, Malke

    2013-01-01

    As a percussive dancer, Malke Rosenfeld makes rhythm with her feet while she dances, and she also helps elementary students make their own percussive dance steps by integrating mathematics into her lesson plans. To do this she uses the Jump Patterns tool, a tool she developed during the first six years of her teaching artist career to help…

  6. Making Movies

    ERIC Educational Resources Information Center

    Crompton, Zoe; Davies, Emma

    2012-01-01

    Children enjoy making movies but can it help them to understand science? In this article, the authors discuss how creating stop-frame animations of salt dissolving can deepen children's understanding of this process. (Contains 1 figure.)

  7. Silver ion high pressure liquid chromatography provides unprecedented separation of sterols: application to the enzymatic formation of cholesta-5,8-dien-3 beta-ol.

    PubMed Central

    Ruan, B; Shey, J; Gerst, N; Wilson, W K; Schroepfer, G J

    1996-01-01

    We report that silver ion HPLC provides remarkable separations of C27 sterols differing only in the number or location of olefinic double bonds. This technique has been extended to LC-MS, analysis of purified components by GC, GC-MS, and 1H NMR, and to its use on a semipreparative scale. The application of this methodology for the demonstration of the catalysis, by rat liver microsomes, of the conversion of 7-dehydrocholesterol to cholesta-5,8-dien-3 beta-ol is also presented. PMID:8876182

  8. Evaluation of S-101 course Supervisors Orientation to Occupational Safety Compliance in DOE'' taught in Richland, Washington May 5--8, 1992

    SciTech Connect

    Wright, T.S.

    1992-09-01

    This report summarizes trainee evaluations for the Safety Training Section course, Supervisors' Orientation to Occupational Safety in DOE'', (S-101)which was conducted May 5--8 at Hanford, in Richland, Washington. Section 1.1 and 1.2 of this report summarizes the quantitative course evaluations that trainees provided upon completion of the course. Appendix A provides a transcript of the trainees' written comments. Numeric course ratings were generally positive and show that the course material and instruction were very effective. Written comments supported the positive numeric ratings. The course content and knowledge gained by the trainees exceeded most of the students' expectations of the course.

  9. Evaluation of S-101 course ``Supervisors Orientation to Occupational Safety Compliance in DOE`` taught in Richland, Washington May 5--8, 1992

    SciTech Connect

    Wright, T.S.

    1992-09-01

    This report summarizes trainee evaluations for the Safety Training Section course, ``Supervisors` Orientation to Occupational Safety in DOE``, (S-101)which was conducted May 5--8 at Hanford, in Richland, Washington. Section 1.1 and 1.2 of this report summarizes the quantitative course evaluations that trainees provided upon completion of the course. Appendix A provides a transcript of the trainees` written comments. Numeric course ratings were generally positive and show that the course material and instruction were very effective. Written comments supported the positive numeric ratings. The course content and knowledge gained by the trainees exceeded most of the students` expectations of the course.

  10. A 5.8nW, 45ppm/°C On-Chip CMOS Wake-up Timer Using a Constant Charge Subtraction Scheme

    PubMed Central

    Jeong, Seokhyeon; Lee, Inhee; Blaauw, David; Sylvester, Dennis

    2015-01-01

    This work presents an ultra-low power oscillator designed for wake-up timers in compact wireless sensors. A constant charge subtraction scheme removes continuous comparator delay from the oscillation period, which is the source of temperature dependence in conventional RC relaxation oscillators. This relaxes comparator design constraints, enabling low power operation. In 0.18µm CMOS, the oscillator consumes 5.8nW at room temperature with temperature stability of 45ppm/°C (−10°C to 90°C) and 1%V line sensitivity. PMID:26778895

  11. Lasing of multiperiod quantum-cascade lasers in the spectral range of (5.6–5.8)-μm under current pumping

    SciTech Connect

    Egorov, A. Yu. Babichev, A. V.; Karachinsky, L. Ya.; Novikov, I. I.; Nikitina, E. V.; Tchernycheva, M.; Sofronov, A. N.; Firsov, D. A.; Vorobjev, L. E.; Pikhtin, N. A.; Tarasov, I. S.

    2015-11-15

    The lasing of multiperiod quantum-cascade lasers in the spectral range of (5.6–5.8)-μm under current pumping are demonstrated. The quantum-cascade laser heterostructure is grown by molecular-beam epitaxy technique. Despite the relatively short laser cavity length and high level of external loss the laser shows the lasing in the temperature range of 80–220 K. The threshold current density below 4 kA/cm{sup 2} at 220 K with the characteristic temperature T{sub 0} = 123 K was demonstrated.

  12. Hypervalent iodine(iii)-promoted N-incorporation into N-aryl vinylogous carbamates to quinoxaline diesters: access to 1,4,5,8-tetraazaphenanthrene.

    PubMed

    Sagar, A; Vidaycharan, Shinde; Shinde, Anand H; Sharada, Duddu S

    2016-04-26

    A novel oxidative N-incorporation strategy for synthesis of quinoxaline diesters under metal-free conditions is described for the first time. The mild reaction conditions allow for this transformation via the formation of two C(sp(2))-N bonds utilizing cheaply available NaN3 as the N-atom source. N-Aryl vinylogous carbamates in this study undergo azidation at enamino C(sp(2))-H selectively. The robustness of this strategy is further demonstrated by the synthesis of a valuable 1,4,5,8-tetraazaphenanthrene derivative using a mild and convenient approach.

  13. Multilevel hierarchy of phase separation processes in La5/8-yPryCa3/8MnO3

    NASA Astrophysics Data System (ADS)

    García-Muñoz, J. L.; Collado, A.; Aranda, M. A. G.; Ritter, C.

    2011-07-01

    We investigate two successive hierarchized phase segregations in La5/8-yPryCa3/8MnO3, which generate ferromagnetic metallic volumes (V1FM and V2FM) having different physical origins, stabilities, and parent electronic phases. The singular percolative transition around TC2 ≈ 100 K is due to a second electronic phase separation (PS), which is specific to the charge-order insulating regions segregated at the first PS process. These findings shed new light on the metastability, atypical dynamics, the nonvolatile magnetoresistance, or the supercooling glass transition in this complex magnetic system.

  14. Tunable Metallicity at La5/8Ca3/8MnO3(001)Surface by Oxygen Overlayer

    SciTech Connect

    Fuchigami, Kenji; Gai, Zheng; Ward, Thomas Z; Yin, Lifeng; Snijders, Paul C; Plummer, E Ward; Shen, Jian

    2009-01-01

    We study the surface structure of La5/8Ca3/8MnO3(001) using in-situ scanning tunnelingmicroscopy (STM). Atomically resolved STM images reveal that a ( 2 " 2)R45oreconstructed surface and a (1 1) surface can be converted back and forth through adsorptionand desorption of oxygen at the surface. Electrical properties of the surfaces are investigated byscanning tunneling spectroscopy (STS). I-V curves clearly show that the presence of an oxygen overlayer renders the surface insulating while the (1 1) surface without the oxygen overlayer is metallic.

  15. Synthesis, structures, electrochemical studies and antioxidant activity of 5-aryl-4-oxo-3,4,5,8-tetrahydropyrido[2,3-d]pyrimidine-7-carboxylic acids

    NASA Astrophysics Data System (ADS)

    Quiroga, Jairo; Romo, Pablo E.; Ortiz, Alejandro; Isaza, José Hipólito; Insuasty, Braulio; Abonia, Rodrigo; Nogueras, Manuel; Cobo, Justo

    2016-09-01

    The synthesis of 5-aryl-4-oxo-3,4,5,8-tetrahydropyrido[2,3-d]pyrimidine-7-carboxylic acids 3 from the reaction of 6-aminopyrimidines 1 with arylidene derivatives of pyruvic acid 2 under microwave and ultrasound irradiation is described. The orientation of cyclization process was determined by NMR measurements. The methodology provides advantages such as high yields and friendly to the environment without the use of solvents. The antioxidant properties, DPPH free radical scavenging, ORAC, and anodic potential oxidation of the new pyridopyrimidines were studied.

  16. Microgravity strategic plan, 1988

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The NASA agency-wide microgravity strategic plan is presented, and its research, applications, and commercialization for the 1990's is addressed. The plan presents an analysis of the current situation, identifies critical factors, and defines goals, objectives, and strategies, which are intended to: (1) provide a context for decision making; (2) assure realism in long-range planning and direction for hardware development; and (3) establish a framework for developing a national microgravity research plan.

  17. Outdoor Classrooms--Planning Makes Perfect

    ERIC Educational Resources Information Center

    Haines, Sarah

    2006-01-01

    Schoolyard wildlife habitats aren't just for beauty and fun--they are outdoor classrooms where real science learning takes place. Schoolyard habitat projects involve conservation and restoration of wildlife habitat; however, the learning doesn't have to stop there--outdoor classrooms can foster many kinds of active learning across the curriculum…

  18. Phylogenetic relationships within the genus Aspidisca (Protozoa, Ciliophora, Euplotida) revealed by ITS1-5.8S-ITS2 region sequences

    NASA Astrophysics Data System (ADS)

    Huang, Jie; Yi, Zhenzhen; Miao, Miao; Al-Rasheid, Khaled A. S.; Song, Weibo

    2011-03-01

    The internal transcribed spacer regions (ITS1 and ITS2) and 5.8S rRNA genes were sequenced in six populations of four Aspidisca species, namely A. leptaspis, A. orthopogon, A. magna and A. aculeata. Phylogenetic trees were constructed by means of Bayesian inference (BI), Maximum Parsimony (MP), Neighbor-Joining (NJ), and Maximum Likelihood (ML) to assess the inter- and intra-species relationships within the genus Aspidisca. All trees show similar topologies with stable supports and indicate that: (1) four well known groups, i.e., Oligotrichia, Stichotrichia, Choreotrichia and Hypotrichia, are distinctly outlined within the class Spirotrichea, and all are monophyletic other than Hypotrichia; (2) members of Aspidisca can be distinguished well, based on the ITS1-5.8S-ITS2 region sequences, and A. leptaspis and A. magna shared a closer relationship than other species; (3) Aspidisca and Euplotes branch early in the subclass Hypotrichia. To compare the phylogenetic relationships based on different genes, SSU rRNA trees were also constructed with nearly the same species inclusion, which revealed different topologies of inter-species, inter-genera and inter-subclasses.

  19. Quantitative measurement on optical attenuation coefficient of cell lines 5-8F and 6-10B using optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Li, Jianghua; Shen, Zhiyuan; He, Yonghong; Tu, Ziwei; Xia, Yunfei; Chen, Changshui; Liu, Songhao

    2012-10-01

    Oncogenesis and metastasis of tumor are difficult to detect during the clinic therapy. To explore the optical properties of tumorigenesis and metastasis in nasopharyngeal carcinoma (NPC), we assessed the NPC cell lines 5-8F and 6-10B by optical coherence tomography (OCT): first, the OCT images of the two different types of cell pellets were captured. Second, by fitting Beer's law to the averaged A-scans in these OCT datasets, the attenuation coefficients (μt) of the cells were extracted. The median attenuation coefficients (interquartile range (IQR)) of 5-8F and 6-10B were 6.79 mm-1 (IQR 6.52 to 7.23 mm-1) versus 8.06 mm-1 (IQR 7.65 to 8.40 mm-1), respectively (p < 0.01, df = 39). Subsequently, the results were compared with those obtained by polarization sensitive OCT, which further confirmed that the quantitative OCT analysis (by μt) could differentiate the oncogenesis and metastasis NPC cell lines in real time non-invasively.

  20. Association between STR -794 CATT5-8 and SNP -173 G/C polymorphisms in the MIF gene and Lepromatous Leprosy in Mestizo patients of western Mexico.

    PubMed

    Martinez-Guzman, M A; Alvarado-Navarro, A; Pereira-Suarez, A L; Muñoz-Valle, J F; Fafutis-Morris, M

    2016-10-01

    Lepromatous Leprosy (LL) is the most common presentation of leprosy in Mexico. LL patients are unable to activate an effective inflammatory response against Mycobacterium leprae probably due to the genetics of the host. Macrophage Migration Inhibitory Factor (MIF) is important to trigger inflammation processes. Two polymorphisms have been reported for human MIF: STR -794 CATT5-8 and SNP -173 G/C. 7-8 CATT repeats at -794 and the C allele at -173 increase the expression of MIF. We aim to determine the association between the polymorphisms in MIF gene and LL. We carried a case and controls study with 100 Mexican LL patients and 100 healthy subjects (HS). PCR was used for genotyping of STR -794 CATT5-8 polymorphism and PCR-RFLP for -173 G/C. We found that LL patients possess high -794 CATT repeats (47.1%) more often than HS (32.7%). In conclusion, a MIF polymorphism is associated with susceptibility to LL in Western Mexican population.

  1. Making Connections

    ERIC Educational Resources Information Center

    Hartley, Tricia

    2007-01-01

    The Campaign for Learning, with its partners NIACE and ContinYou, established the National Family Learning Network (NFLN) in 2001. Most of the expertise in any field, including family learning, exists at grassroots level, but all too often stays at the very local, even single-institutional, level, because structures make effective sharing on a…

  2. Making Connections

    ERIC Educational Resources Information Center

    Turner, Paul

    2015-01-01

    This article aims to illustrate a process of making connections, not between mathematics and other activities, but within mathematics itself--between diverse parts of the subject. Novel connections are still possible in previously explored mathematics when the material happens to be unfamiliar, as may be the case for a learner at any career stage.…

  3. Making Lemonade

    ERIC Educational Resources Information Center

    Peterson, Erin

    2009-01-01

    In the current economic climate, alumni associations are taking hard looks at their budgets and making cuts where necessary. However, the recession is an opportunity for alumni associations to create and build alumni loyalty through networking and career services--when they are needed most. Many alumni association budgets are set through the end…

  4. Macrophage migration inhibitory factor (MIF) promoter polymorphisms (-794 CATT5-8 and -173 G>C): association with MIF and TNFα in psoriatic arthritis

    PubMed Central

    Morales-Zambrano, Ramsés; Bautista-Herrera, Luis A; la Cruz-Mosso, Ulises De; Villanueva-Quintero, Guadalupe D; Padilla-Gutiérrez, Jorge R; Valle, Yeminia; Parra-Rojas, Isela; Rangel-Villalobos, Héctor; Gutiérrez-Ureña, Sergio R; Muñoz-Valle, José F

    2014-01-01

    Psoriatic arthritis (PsA) is an autoimmune disease with a complex interaction of gene and with a dysregulation of pro-inflammatory cytokine such as Macrophage migration Inhibitory Factor (MIF) and Tumor Necrosis Factor-alpha (TNFα). Two polymorphisms identified in the promoter region of the MIF gene have been described: the STR-794 CATT5-8 (rs5844572) and the SNP-173 G>C (rs755622), which are associated with increased MIF levels in circulation and with autoimmune diseases in several populations. In this case-control study we investigated whether commonly occurring functional MIF polymorphisms are associated with PsA susceptibility and clinical variables as well as with MIF and TNFα serum levels in a Mexican-Mestizo population. Genotyping of the -794 CATT5-8 and -173 G>C MIF polymorphisms was performed by PCR and PCR-RFLP respectively in 50 PsA patients and 100 healthy subjects (HS). MIF and TNFα serum levels were determined by ELISA. A significant increase of MIF (PsA: 7.8 vs. HS: 5.25 ng/mL; p < 0.001) and TNFα (PsA: 24.6 vs. HS: 9.9 pg/mL; p < 0.001) levels was found in PsA patients, a significant correlation was observed between MIF and TNFα (r = 0.41; p < 0.01). The 5,6 repeats genotype of the -794 CATT5-8 MIF was associated with protection to PsA (OR = 0.29; CI 0.77-0.98; p = 0.03), and the G/C genotype (OR = 7.5; CI 2.92-21.64; p < 0.001) and the -173*C allele (OR = 2.45; CI 1.43-4.20; p < 0.001) of the -173 G>C MIF were associated with susceptibility to PsA. In conclusion the -173*C allele is associated with susceptibility to PsA in Mexican-Mestizo population, whereas the correlation between MIF and TNFα soluble levels provided evidence that both cytokines are closely related in the pathophysiology of the PsA. PMID:25356116

  5. Macrophage migration inhibitory factor (MIF) promoter polymorphisms (-794 CATT5-8 and -173 G>C): association with MIF and TNFα in psoriatic arthritis.

    PubMed

    Morales-Zambrano, Ramsés; Bautista-Herrera, Luis A; De la Cruz-Mosso, Ulises; Villanueva-Quintero, Guadalupe D; Padilla-Gutiérrez, Jorge R; Valle, Yeminia; Parra-Rojas, Isela; Rangel-Villalobos, Héctor; Gutiérrez-Ureña, Sergio R; Muñoz-Valle, José F

    2014-01-01

    Psoriatic arthritis (PsA) is an autoimmune disease with a complex interaction of gene and with a dysregulation of pro-inflammatory cytokine such as Macrophage migration Inhibitory Factor (MIF) and Tumor Necrosis Factor-alpha (TNFα). Two polymorphisms identified in the promoter region of the MIF gene have been described: the STR-794 CATT5-8 (rs5844572) and the SNP-173 G>C (rs755622), which are associated with increased MIF levels in circulation and with autoimmune diseases in several populations. In this case-control study we investigated whether commonly occurring functional MIF polymorphisms are associated with PsA susceptibility and clinical variables as well as with MIF and TNFα serum levels in a Mexican-Mestizo population. Genotyping of the -794 CATT5-8 and -173 G>C MIF polymorphisms was performed by PCR and PCR-RFLP respectively in 50 PsA patients and 100 healthy subjects (HS). MIF and TNFα serum levels were determined by ELISA. A significant increase of MIF (PsA: 7.8 vs. HS: 5.25 ng/mL; p < 0.001) and TNFα (PsA: 24.6 vs. HS: 9.9 pg/mL; p < 0.001) levels was found in PsA patients, a significant correlation was observed between MIF and TNFα (r = 0.41; p < 0.01). The 5,6 repeats genotype of the -794 CATT5-8 MIF was associated with protection to PsA (OR = 0.29; CI 0.77-0.98; p = 0.03), and the G/C genotype (OR = 7.5; CI 2.92-21.64; p < 0.001) and the -173*C allele (OR = 2.45; CI 1.43-4.20; p < 0.001) of the -173 G>C MIF were associated with susceptibility to PsA. In conclusion the -173*C allele is associated with susceptibility to PsA in Mexican-Mestizo population, whereas the correlation between MIF and TNFα soluble levels provided evidence that both cytokines are closely related in the pathophysiology of the PsA.

  6. Crystallinity and interface of 1,4,5,8,9,11-hexaazatriphenylene-hexacarbonitrile thin films between organic and transparent conductive oxide layers

    NASA Astrophysics Data System (ADS)

    Lee, Hyun Hwi; Lee, Jeong-Hwan; Kim, Jang-Joo; Kim, Hyo Jung

    2015-05-01

    The crystallinity, preferential ordering, and interfacial stability of 1,4,5,8,9,11-hexaazatriphenylene-hexacarbonitrile (HATCN) thin films interconnected with organic/inorganic multilayers have been investigated. In the region close to the organic-organic interface, HATCN formed a low crystalline order with a substantial amorphous phase. As film growth continued, HATCN stacked to the high crystalline ordered phase. After the sputtering deposition of the indium zinc oxide (IZO) layer on top, the volume fraction of the preferentially ordered region of HATCN increased without any structural deterioration. In addition, the HATCN surface was kept quite stable by preserving the sharp interface between the HATCN and sputtering-deposited IZO layers.

  7. High-performance hybrid buffer layer using 1,4,5,8,9,11-hexaazatriphenylenehexacarbonitrile/molybdenum oxide in inverted top-emitting organic light-emitting diodes.

    PubMed

    Park, Cheol Hwee; Lee, Hyun Jun; Hwang, Ju Hyun; Kim, Kyu Nyun; Shim, Yong Sub; Jung, Sun-Gyu; Park, Chan Hyuk; Park, Young Wook; Ju, Byeong-Kwon

    2015-03-25

    A high-performance 1,4,5,8,9,11-hexaazatriphenylenehexacarbonitrile (HATCN)/molybdenum oxide (MoO3) hybrid buffer layer with high hole-injection efficiency and superior plasma resistance under the sputtering process was developed. The HATCN enhances the hole-injection efficiency, and the MoO3 effectively protects the underlying organic layers from plasma damage during deposition by sputtering. This improves the characteristics of inverted top-emitting organic light-emitting diodes using a top transparent conductive oxide electrode. The device using the hybrid buffer layer showed the highest electroluminescence characteristics among devices with other buffer layers. The high hole-injection efficiency of HATCN was shown by the J-F curve of hole-only devices, and the plasma protection performance of MoO3 was shown by atomic force microscope surface morphology images of the buffer layer film after O2 plasma treatment.

  8. Fiber tracking of the frontal aslant tract and subcomponents of the arcuate fasciculus in 5-8-year-olds: Relation to speech and language function.

    PubMed

    Broce, Iris; Bernal, Byron; Altman, Nolan; Tremblay, Pascale; Dick, Anthony Steven

    2015-10-01

    Long association cortical fiber pathways support developing networks for speech and language, but we do not have a clear understanding of how they develop in early childhood. Using diffusion-weighted imaging (DWI) we tracked the frontal aslant tract (FAT), arcuate fasciculus (AF), and AF segments (anterior, long, posterior) in 19 typical 5-8-year-olds, an age range in which significant improvement in speech and language function occurs. While the microstructural properties of the FAT and the right AF did not show age-related differences over the age range we investigated, the left AF evidenced increasing fractional anisotropy with age. Microstructural properties of the AF in both hemispheres, however, predicted receptive and expressive language. Length of the left FAT also predicted receptive language, which provides initial suggestion that this pathway is important for language development. These findings have implications for models of language development and for models of the neurobiology of language more broadly.

  9. Fucoidan promotes osteoblast differentiation via JNK- and ERK-dependent BMP2-Smad 1/5/8 signaling in human mesenchymal stem cells.

    PubMed

    Kim, Beom Su; Kang, Hyo-Jin; Park, Ji-Yun; Lee, Jun

    2015-01-01

    Fucoidan has attracted attention as a potential drug because of its biological activities, which include osteogenesis. However, the molecular mechanisms involved in the osteogenic activity of fucoidan in human alveolar bone marrow-derived mesenchymal stem cells (hABM-MSCs) remain largely unknown. We investigated the action of fucoidan on osteoblast differentiation in hABM-MSCs and its impact on signaling pathways. Its effect on proliferation was determined using the crystal violet staining assay. Osteoblast differentiation was evaluated based on alkaline phosphatase (ALP) activity and the mRNA expression of multiple osteoblast markers. Calcium accumulation was determined by Alizarin red S staining. We found that fucoidan induced hABM-MSC proliferation. It also significantly increased ALP activity, calcium accumulation and the expression of osteoblast-specific genes, such as ALP, runt-related transcription factor 2, type I collagen-α 1 and osteocalcin. Moreover, fucoidan induced the expression of bone morphogenetic protein 2 (BMP2) and stimulated the activation of extracellular signal-related kinase (ERK), c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase by increasing phosphorylation. However, the effect of fucoidan on osteogenic differentiation was inhibited by specific inhibitors of ERK (PD98059) and JNK (SP600125) but not p38 (SB203580). Fucoidan enhanced BMP2 expression and Smad 1/5/8, ERK and JNK phosphorylation. Moreover, the effect of fucoidan on osteoblast differentiation was diminished by BMP2 knockdown. These results indicate that fucoidan induces osteoblast differentiation through BMP2-Smad 1/5/8 signaling by activating ERK and JNK, elucidating the molecular basis of the osteogenic effects of fucoidan in hABM-MSCs.

  10. Evolutionary dynamics and preferential expression of homeologous 18S-5.8S-26S nuclear ribosomal genes in natural and artificial glycine allopolyploids.

    PubMed

    Joly, Simon; Rauscher, Jason T; Sherman-Broyles, Susan L; Brown, A H D; Doyle, Jeff J

    2004-07-01

    Polyploidy is an important evolutionary process in plants, but much remains to be learned about the evolution of gene expression in polyploids. Evolution and expression of the 18S-5.8S-26S ribosomal gene family was investigated at homeologous loci in the Glycine subgenus Glycine perennial soybean polyploid complex, which consists of several diploid genomes that have formed allopolyploids in various combinations, often recurrently. A semiquantitative PCR method targeting the internal transcribed spacer (ITS) of the 18S-5.8S-26S nuclear ribosomal DNA (nrDNA) was used to survey the ratio between homeologous repeats in polyploid genomes and to test for preferential expression of homeologous nrDNA loci. Most natural polyploids possess one predominant nrDNA homeolog in their genome. Analysis of F2 segregation in an artificial cross suggested that in some plants, most or all repeats at one homeologous locus have been lost, whereas in other plants two loci remain, but both have been homogenized by concerted evolution. In most natural allopolyploids harboring a relatively balanced ratio of homeologs, one homeolog was expressed preferentially, but in the majority of plants, low levels of transcription could be detected from the other homeolog. Individuals within some tetraploid taxa varied as to which homeolog was expressed preferentially. In some plants, the degree of preferential expression also varied among tissues. Preferential expression was absent in synthetic polyploids and in some artificial diploid hybrids, suggesting that nucleolar dominance is not necessarily a direct result of hybridization or polyploidization. The establishment of preferential expression in Glycine allopolyploids appears to be either stochastic within lineages or genotype specific. PMID:15084677

  11. Effect of cation site-disorder on the structure and magneto-transport properties of Ln5/8M3/8MnO 3 manganites

    NASA Astrophysics Data System (ADS)

    Collado, J. A.; Frontera, C.; García-Muñoz, J. L.; Aranda, M. A. G.

    2005-06-01

    Five members of Ln5/8M3/8MnO 3 series with A-cation size variance ( σ2) ranging between 3×10 -4 and 71×10 -4 Å 2, and the same A-cation size =1.2025 Å, have been synthesized by the ceramic method. The five manganites are single phase and they crystallize in the Pnma perovskite superstructure. The five compositions display ferromagnetic-paramagnetic transitions at temperatures ranging between 130 and 270 K, for the highest and lowest variance sample, respectively. The samples with smaller variances show sharp magnetization transitions and the samples with the larger variances display broad transitions. These transitions have also been studied by differential scanning calorimetry, DSC, and some enthalpy changes are reported. The resistivity study indicates that all samples display the expected metal-to-insulator transitions at temperatures ranging between 140 and 270 K. The samples have been analysed at room temperature by ultra-high-resolution synchrotron powder diffraction and the structural and microstructural features are reported. Furthermore, Nd 5/8Sr 0.255Ca 0.12MnO 3 ( σ2=40×10-4 Å2) and Sm 0.225Nd 0.4Sr 0.308Ca 0.067MnO 3 ( σ2=53×10-4 Å2) samples have also been studied by synchrotron powder diffraction at 140 K, below the transition temperatures. Both samples are found to be single phase above and below the transition by ultra-high-resolution synchrotron powder diffraction. The microstructure of the samples has been investigated through Williamson-Hall plots. Sample broadenings are markedly anisotropic and strongly dominated by microstrains with average values of the Δ d/ d term close to 14×10 -4. A direct correlation is found between the microstrain values and the widths of the magnetization transitions.

  12. Manpower and project planning

    NASA Technical Reports Server (NTRS)

    Johnson, David W.

    1991-01-01

    The purpose was to study how manpower and projects are planned at the Facilities Engineering Division (FENGD) within the Systems Engineering and Operations Directorate of the LaRC and to make recommendations for improving the effectiveness and productivity ot the tools that are used. The existing manpower and project planning processes (including the management plan for the FENGD, existing manpower planning reports, project reporting to LaRC and NASA Headquarters, employee time reporting, financial reporting, and coordination/tracking reports for procurement) were discussed with several people, and project planning software was evaluated.

  13. News Expedition: Teachers go on extreme journey Summer School: Summer school inspires student Conference: Bristol plans science teaching festival Teacher Support: Make the most of your SPN support Conference: Schools can use latest physics Web Resource: Datamouse online project goes live Forthcoming Events

    NASA Astrophysics Data System (ADS)

    2010-01-01

    Expedition: Teachers go on extreme journey Summer School: Summer school inspires student Conference: Bristol plans science teaching festival Teacher Support: Make the most of your SPN support Conference: Schools can use latest physics Web Resource: Datamouse online project goes live Forthcoming Events

  14. The Variation of Brune Stress Drop with Hypocentral Depth for Moderate (3.4 ≤ M ≤ 5.8) Earthquakes in Northeastern North America

    NASA Astrophysics Data System (ADS)

    Boatwright, J.; MacDonald, T.

    2011-12-01

    We analyze broadband (0.05 to 30 Hz) Fourier spectra of S+Lg+surface wave groups from 16 moderate (3.4 ≤ M ≤ 5.8) earthquakes, obtained from the horizontal components of Canadian and American seismographs and accelerographs sited on rock at hypocentral distances from 11 to 625 km. Nine of the earthquakes, including the 1988 M5.8 Saguenay and 2005 M4.6 Rivière-du-Loup earthquakes, are located in a broad area around Charlevoix, on the St. Lawrence Seaway. Four of the earthquakes, including the 2010 M5.0 Val-des-Bois earthquake, are located in the Western Quebec Seismic Zone (WQSZ), which extends NNW through Ottawa from the upper St. Lawrence River. Attenuation analysis of 7 small earthquakes in eastern Quebec and New England corroborates the attenuation model Q = 410f^{0.5} obtained by Boatwright and Seekins (2011) for ray paths in the Appalachian and southeastern Grenville Provinces. The Brune stress drops for the Charlevoix earthquakes are more strongly correlated with hypocentral depth (r = 0.93) than with moment magnitude (r = 0.65). The Saguenay earthquake is the largest and deepest (h = 29 km) of these earthquakes and has the largest stress drop (Δσ = 419 bars). For ray paths to the east and south from the WQSZ, we obtain Q = (412±26)f^{0.50±0.03}; for ray paths to the west from the WQSZ, we obtain Q = (580±64)f^{0.46±0.05}. We use both attenuation models to analyze the four WQSZ earthquakes, and group them together with the 2000 M4.6 Kipawa and 2002 M5.0 Ausable Forks earthquakes. The Brune stress drops for these six events are weakly correlated with depth (r = 0.53) and uncorrelated with moment magnitude (r = 0.05). The Charlevoix earthquakes extend to greater depth and have a higher average stress drop (202 bars) than the WQSZ earthquakes (129 bars). Including the depth dependence of the stress drop in a probabilistic seismic hazard analysis for the Charlevoix area significantly reduces the predicted ground motion, by reducing the probability of a

  15. Acenocoumarol sensitivity and pharmacokinetic characterization of CYP2C9 *5/*8,*8/*11,*9/*11 and VKORC1*2 in black African healthy Beninese subjects.

    PubMed

    Allabi, Aurel Constant; Horsmans, Yves; Alvarez, Jean-Claude; Bigot, André; Verbeeck, Roger K; Yasar, Umit; Gala, Jean-Luc

    2012-06-01

    This study aimed at investigating the contribution of CYP2C9 and VKORC1 genetic polymorphisms to inter-individual variability of acenocoumarol pharmacokinetics and pharmacodynamics in Black Africans from Benin. Fifty-one healthy volunteers were genotyped for VKORC1 1173C>T polymorphism. All of the subjects had previously been genotyped for CYP2C9*5, CYP2C9*6, CYP2C9*8, CYP2C9*9 and CYP2C9*11 alleles. Thirty-six subjects were phenotyped with a single 8 mg oral dose of acenocoumarol by measuring plasma concentrations of (R)- and (S)-acenocoumarol 8 and 24 h after the administration using chiral liquid-chromatography tandem mass-spectrometry. International normalized ratio (INR) values were determined prior to and 24 h after the drug intake. The allele frequency of VKORC1 variant (1173C>T) was 1.96% (95% CI 0.0-4.65%). The INR values did not show statistically significant difference between the CYP2C9 genotypes, but were correlated with body mass index and age at 24 h post-dosing (P < 0.05). At 8 h post dose, the (S)-acenocoumarol concentrations in the CYP2C9*5/*8 and CYP2C9*9/*11 genotypes were about 1.9 and 5.1 fold higher compared with the CYP2C9*1/*1 genotype and 2.2- and 6.0-fold higher compared with the CYP2C9*1/*9 group, respectively. The results indicated that pharmacodynamic response to acenocoumarol is highly variable between the subjects. This variability seems to be associated with CYP2C9*5/*8 and *9/*11 variant and demographic factors (age and weight) in Beninese subjects. Significant association between plasma (S)-acenocoumarol concentration and CYP2C9 genotypes suggested the use of (S)-acenocoumarol for the phenotyping purpose. Larger number of subjects is needed to study the effect of VKORC1 1173C>T variant due to its low frequency in Beninese population. PMID:21811894

  16. Seismotectonics of the Antalya Basin and surrounding regions in eastern Mediterranean from 8 to 28 December 2013 Mw 5.0-5.8 earthquake sequence

    NASA Astrophysics Data System (ADS)

    Görgün, Ethem; Kalafat, Doğan; Kekovalı, Kıvanç

    2016-05-01

    The 8-28 December 2013 Mw 5.0-5.8 Antalya Basin earthquake sequence in eastern Mediterranean is examined. Centroid moment tensors for 16 earthquakes with moment magnitudes (Mw) between 3.6 and 5.8 are determined by applying a waveform inversion method. All earthquakes are shallow focus thrust events at a depth of 40-45 km. The seismic moments (Mo) of the earthquakes are estimated as 4.10 × 1016-5.54 × 1017 N m and rupture durations of the mainshocks are 20-22 s. The focal mechanisms of the aftershocks are mainly thrust faulting with a strike-slip component and reveal NW-SE trending direction of T-axis in the entire activated region. According to high-resolution hypocenter relocation of the Antalya earthquake sequence, seven main clusters are revealed. The aftershock activity in the observation period between 1 December 2013 and 23 January 2015 extends in an N to S direction. A seismic cross-section indicates that a complex pattern of the hypocenter distribution with the activation of seven segments. The westernmost cluster (cluster 1) is associated with a fault plane trending mainly WNW-ESE and dipping vertical, while the cluster 5 is related to a fault plane trending NNE-SSW and dipping towards SSE. The best constrained focal depths indicate that the aftershock sequence is mainly confined in the crust (depth < 40 km) and are operating in the approximate depth range from 3 to 110 km. A stress tensor inversion of focal mechanism data is performed to obtain a more precise picture of the Antalya Basin stress field. The stress tensor inversion results indicate a predominant thrust stress regime with a NE-SW oriented maximum horizontal compressive stress (SH). According to variance of the stress tensor inversion, to first order, the Antalya Basin is characterized by a homogeneous interplate stress field. The Coulomb stress change associated with two mainshocks are also investigated to evaluate any significant enhancement of stresses along the Antalya Basin and

  17. Making Aliens

    NASA Astrophysics Data System (ADS)

    Andreadis, A.

    During the next few decades, the decisions we make will determine the future of our biosphere and our species. In this context, space exploration will literally answer a question that has preoccupied us ever since we became self-aware: What is going to happen to us? Reaching and inhabiting other planets is often considered an extension of human exploration and occupation of Earth but the analogy is useful only as a metaphor. Whatever the extremes of Earth, we can live almost everywhere on it because we started and evolved here. Given the vagaries of chance in every event of planetmaking, we will never find an Earth twin. To live under strange skies will require courage, ingenuity and stamina ­ but above all, it will require a hard look at our assumptions, including what it means to be human.

  18. Making waves.

    NASA Astrophysics Data System (ADS)

    Townes, C. H.

    The author takes the reader on a behind-the-scenes tour of his way of working. Along the way, one learns about how the author came upon his surprising findings and how he managed to avoid obstacles in his path. He introduces the reader to the wonders of the universe, from the submicroscopic, most minute - the workings of atoms and the even smaller particles that make them up - to the vast outer reaches of space. His tour takes one along paths Townes pioneered: quantum electronics, microwave spectroscopy and the frontiers of our galaxy where he explored the dark, rarefied clouds of gas and dust where new stars form. The book concludes with a uniquely personal coda in which Townes suggests that science and religion occupy the same terrain.

  19. NAEA's Strategic Plans

    ERIC Educational Resources Information Center

    School Arts: The Art Education Magazine for Teachers, 2004

    2004-01-01

    NAEA began long-range planning in 1982, when a Long-Range Planning Commission was formed to make recommendations to improve the status of the art education profession five to ten years ahead. This commission made specific recommendations to improve the status of art in American education and to support professional growth for NAEA members. This…

  20. Design analysis and full scale prototype testing of Auger TLP`s 9-5/8 inch TLP production riser weld-on connector

    SciTech Connect

    Fox, S.A.; Smith, J.D.; Asbill, W.T.

    1995-12-31

    The design, analysis, and full-scale prototype testing of a special threaded connector for use on the Auger TLP 9-5/8 inch x 0.435 inch wall production risers is summarized in this paper. A flush-bore production riser connector with internal and external metal-to-metal seals, a resilient seal between the external metal-to-metal seal and the external torque shoulder, radial thread interference, and high resistance to fatigue was developed. Finite element analyses and full-scale static, sealability, and fatigue tests verified that the connector satisfied all design requirements. The full-scale fatigue tests verified that the design fatigue curve and fatigue life prediction procedure used yield conservative results and that the fatigue life of the connector greatly exceeds the girthweld. Consideration of manufacturing methods and tolerances along with gauging, in the early stages of the design, resulted in a cost effective connector. The threaded connector was designed for the Auger Tension Leg Platform production risers. However, it is envisioned that the connector will be easily scalable to other riser diameters and wall thicknesses for other TLP`s and has applicability to catenary and top-tensioned risers and subsea flowlines. In addition to resulting in an efficient long life production riser connector design, the design process illustrated the Importance of interaction, between the designers, quality control personnel, machinist, gauge manufacturer, and end user, during the design. All made significant contributions to the success of the design.

  1. Modeling and Simulation of a 5.8kV SiC PiN Diode for Inductive Pulsed Plasma Thruster Applications

    NASA Technical Reports Server (NTRS)

    Toftul, Alexandra; Hudgins, Jerry L.; Polzin, Kurt A.; Martin, Adam K.

    2014-01-01

    Current ringing in an Inductive Pulsed Plasma Thruster (IPPT) can lead to reduced energy efficiency, excess heating, and wear on circuit components such as capacitors and solid state devices. Clamping off the current using a fast turn-off power diode is an effective way to reduce current ringing and increase energy efficiency. A diode with a shorter reverse recovery time will allow the least amount of current to ring back through the circuit, as well as minimize switching losses. The reverse recovery response of a new 5.8 kilovolt SiC PiN diode from Cree, Inc. in the IPPT plasma drive circuit is investigated using a physicsbased Simulink model, and compared with that of a 5SDF 02D6004 5.5 kilovolt fast-switching Si diode from ABB. Parameter extraction was carried out for each diode using both datasheet specifications and experimental waveforms, in order to most accurately adapt the model to the specific device. Further experimental data will be discussed using a flat-plate IPPT developed at NASA Marshall Space Flight Center and used to verify the simulation results. A final quantitative measure of circuit efficiency will be described for both the Si and SiC diode configuration.

  2. Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.

    PubMed

    Apro, Johanna; Beckman, Lena; Angelin, Bo; Rudling, Mats

    2015-06-12

    Previous studies have indicated that dietary intake of sugar may lower bile acid production, and may promote cholesterol gallstone formation in humans. We studied the influence of dietary sucrose on cholesterol and bile acid metabolism in the rat. In two different experiments, rats received high-sucrose diets. In the first, 60% of the weight of standard rat chow was replaced with sucrose (high-sucrose diet). In the second, rats received a diet either containing 65% sucrose (controlled high-sucrose diet) or 65% complex carbohydrates, in order to keep other dietary components constant. Bile acid synthesis, evaluated by measurements of the serum marker 7-alpha-hydroxy-4-cholesten-3-one (C4) and of the hepatic mRNA expression of Cyp7a1, was markedly reduced by the high-sucrose diet, but not by the controlled high-sucrose diet. Both diets strongly reduced the hepatic - but not the intestinal - mRNA levels of Abcg5 and Abcg8. The differential patterns of regulation of bile acid synthesis induced by the two sucrose-enriched diets indicate that it is not sugar per se in the high-sucrose diet that reduces bile acid synthesis, but rather the reduced content of fiber or fat. In contrast, the marked reduction of hepatic Abcg5/8 observed is an effect of the high sugar content of the diets.

  3. Genetic diversity of Histoplasma and Sporothrix complexes based on sequences of their ITS1-5.8S-ITS2 regions from the BOLD System.

    PubMed

    Estrada-Bárcenas, Daniel Alfonso; Vite-Garín, Tania; Navarro-Barranco, Hortensia; de la Torre-Arciniega, Raúl; Pérez-Mejía, Amelia; Rodríguez-Arellanes, Gabriela; Ramirez, Jose Antonio; Humberto Sahaza, Jorge; Taylor, Maria Lucia; Toriello, Conchita

    2014-01-01

    High sensitivity and specificity of molecular biology techniques have proven usefulness for the detection, identification and typing of different pathogens. The ITS (Internal Transcribed Spacer) regions of the ribosomal DNA are highly conserved non-coding regions, and have been widely used in different studies including the determination of the genetic diversity of human fungal pathogens. This article wants to contribute to the understanding of the intra- and interspecific genetic diversity of isolates of the Histoplasma capsulatum and Sporothrix schenckii species complexes by an analysis of the available sequences of the ITS regions from different sequence databases. ITS1-5.8S-ITS2 sequences of each fungus, either deposited in GenBank, or from our research groups (registered in the Fungi Barcode of Life Database), were analyzed using the maximum likelihood (ML) method. ML analysis of the ITS sequences discriminated isolates from distant geographic origins and particular wild hosts, depending on the fungal species analyzed. This manuscript is part of the series of works presented at the "V International Workshop: Molecular genetic approaches to the study of human pathogenic fungi" (Oaxaca, Mexico, 2012).

  4. Effect of silver doping on the surface of La5/8Ca3/8MnO3 epitaxial films

    NASA Astrophysics Data System (ADS)

    Tselev, A.; Vasudevan, R. K.; Kalinin, S. V.; Baddorf, A. P.

    2014-09-01

    Thin film manganese oxides (manganites) display remarkable properties, such as colossal magnetoresistance and charge ordered phases, and became a focal point of research in the past two decades owing to potential applications ranging from oxide spintronics to resistive switching-based memories. LaxCa1-xMnO3 (LCMO), a widely studied manganite, is known to substantially improve its transport properties when doped with Ag. However, despite the abundance of studies on LCMO, the effect of silver on the surface structure is unknown. Here, through in-situ methods, scanning tunneling microscopy (STM) is performed on La5/8Ca3/8MnO3 films grown by pulsed laser deposition. Films doped by silver, as confirmed by in-situ X-ray photoelectron spectroscopy, display large-scale reconstructions, interpreted as being of type (√10 × √10)R18.4°, while films lacking silver display a (√2 × √2)R45° reconstruction that may be associated with a surface charge-ordered state. It is posited that the possible cause of the varied reconstructions is due to a vacancy ordering on top of the existing (√2 × √2)R45° reconstruction. These studies highlight the influence of Ag on the surface structure, and therefore a route towards modifying the surface properties of manganites.

  5. Shear Wave Velocity and Site Amplification Factors for 25 Strong-Motion Instrument Stations Affected by the M5.8 Mineral, Virginia, Earthquake of August 23, 2011

    USGS Publications Warehouse

    Kayen, Robert; Carkin, Bradley; Corbett, Skye; Zangwill, Aliza; Estevez, Ivan; Lai, Lena

    2015-01-01

    Vertical one-dimensional shear wave velocity (Vs) profiles are presented for 25 strong-motion instrument sites along the Mid-Atlantic eastern seaboard, Piedmont region, and Appalachian region, which surround the epicenter of the M5.8 Mineral, Virginia, Earthquake of August 23, 2011. Testing was performed at sites in Pennsylvania, Maryland, West Virginia, Virginia, the District of Columbia, North Carolina, and Tennessee. The purpose of the study is to determine the detailed site velocity profile, the average velocity in the upper 30 meters of the profile (VS,30), the average velocity for the entire profile (VS,Z), and the National Earthquake Hazards Reduction Program (NEHRP) site classification. The Vs profiles are estimated using a non-invasive continuous-sine-wave method for gathering the dispersion characteristics of surface waves. A large trailer-mounted active source was used to shake the ground during the testing and produce the surface waves. Shear wave velocity profiles were inverted from the averaged dispersion curves using three independent methods for comparison, and the root-mean square combined coefficient of variation (COV) of the dispersion and inversion calculations are estimated for each site.

  6. A series of low-altitude aerial radiological surveys of selected regions within Areas 3, 5, 8, 9, 11, 18, and 25 at the Nevada Test Site

    SciTech Connect

    Colton, D.P.

    1999-12-01

    A series of low-altitude, aerial radiological surveys of selected regions within Areas 3, 5, 8, 9, 11, 18,and 25 of the Nevada Test Site was conducted from December 1996 through June 1999. The surveys were conducted for the US Department of Energy by the Remote Sensing Laboratory, located in Las Vegas, Nevada, and maintained and operated by Bechtel Nevada. The flights were conducted at a nominal altitude of 15 meters above ground level along a set of parallel flight lines spaced 23 meters apart. The purpose of these low-altitude surveys was to measure, map, and define the areas of americium-241 activity. The americium contamination will be used to determine the areas of plutonium contamination. Americium-241 activity was detected within 8 of the 11 regions. The three regions where americium-241 was not detected were in the inactive Nuclear Rocket Development Station complex in Area 25, which encompassed the Test Cell A and Test Cell C reactor test stands and the Reactor Maintenance Assembly and Disassembly facility.

  7. The effect of iron content and dissolved O2 on dissolution rates of clinopyroxene at pH 5.8 and 25°C: Preliminary results

    USGS Publications Warehouse

    Hoch, A.R.; Reddy, M.M.; Drever, J.I.

    1996-01-01

    Dissolution experiments using augite (Mg0.87Ca0.85Fe0.19Na0.09Al0.03Si2O6) and diopside (Mg0.91Ca0.93Fe0.07Na0.03Al0.03Si2O6) were conducted in flow-through reactors (5-ml/h flow rate). A pH of 5.8 was maintained by bubbling pure CO2 through a solution of 0.01 M KHCO3 at 25°C. Two experiments were run for each pyroxene type. In one experiment dissolved O2 concentration in reactors was 0.6 (±0.1) ppm and in the second dissolved O2 was 1.5 (±0.1) ppm. After 60 days, augite dissolution rates (based on Si release) were approximately three times greater in the 1.5 ppm. dissolved O2 experiments than in the sealed experiments. In contrast, diopside dissolution rates were independent of dissolved O2 concentrations. Preliminary results from the augite experiments suggest that dissolution rate is directly related to oxidation of iron. This effect was not observed in experiments performed on iron-poor diopside. Additionally, dissolution rates of diopside were much slower than those of augite, again suggesting a relationship between Fe content, Fe oxidation and dissolution rates.

  8. Cheyne-Stokes respiration in congestive heart failure: continuous positive airway pressure of 5-8 cm H2O for 1 year in five cases.

    PubMed

    Yasuma, Fumihiko

    2005-01-01

    Five adult patients with congestive heart failure (CHF) due to dilated cardiomyopathy complicated by Cheyne-Stokes respiration/central sleep apnea (CSR/CSA) were treated with continuous positive airway pressure (CPAP) with an initial pressure of 5 cm H2O. Four patients were followed up for 12 months with CPAP of 5 cm H2O. The rest, a 93-year-old patient, was followed up for 30 months, and the CPAP was reset at 8 cm H2O due to worsened cardiac function after 6 months and it was reset at 6 cm H2O due to dryness of the nose after 23 months. For all the patients with nightly CPAP use for 6.0+/-1.4 h per day for a year, frequency of CSR/CSA was significantly reduced after 3 and 12 months with CPAP (p<0.05). Moreover, their symptoms, cardiac function and sleep quality were significantly improved after 3 months (p<0.05), and were maintained above the pre-CPAP levels after 12 months, except for the oldest patient whose cardiac function tended to deteriorate. The results suggest that CSR/CSA in CHF can be treated with CPAP set at a lower pressure than the conventional method, and that CPAP at 5-8 cm H2O is often effective in eliminating CSR/CSA, improving sleep quality, and presumably maintaining cardiac function.

  9. Effect of silver doping on the surface of La{sub 5/8}Ca{sub 3/8}MnO{sub 3} epitaxial films

    SciTech Connect

    Tselev, A. Vasudevan, R. K.; Kalinin, S. V.; Baddorf, A. P.

    2014-09-08

    Thin film manganese oxides (manganites) display remarkable properties, such as colossal magnetoresistance and charge ordered phases, and became a focal point of research in the past two decades owing to potential applications ranging from oxide spintronics to resistive switching-based memories. La{sub x}Ca{sub 1−x}MnO{sub 3} (LCMO), a widely studied manganite, is known to substantially improve its transport properties when doped with Ag. However, despite the abundance of studies on LCMO, the effect of silver on the surface structure is unknown. Here, through in-situ methods, scanning tunneling microscopy (STM) is performed on La{sub 5/8}Ca{sub 3/8}MnO{sub 3} films grown by pulsed laser deposition. Films doped by silver, as confirmed by in-situ X-ray photoelectron spectroscopy, display large-scale reconstructions, interpreted as being of type (√10 × √10)R18.4°, while films lacking silver display a (√2 × √2)R45° reconstruction that may be associated with a surface charge-ordered state. It is posited that the possible cause of the varied reconstructions is due to a vacancy ordering on top of the existing (√2 × √2)R45° reconstruction. These studies highlight the influence of Ag on the surface structure, and therefore a route towards modifying the surface properties of manganites.

  10. Effect of silver doping on the surface of La5/8Ca3/8MnO3 epitaxial films

    SciTech Connect

    Tselev, Alexander; Vasudevan, Rama K; Kalinin, Sergei V; Baddorf, Arthur P

    2014-01-01

    Thin film manganese oxides (manganites) display remarkable properties such as colossal magnetoresistance and charge ordered phases, and became a focal point of research in the past two decades owing to potential applications ranging from oxide spintronics to resistive switching-based memories. LaxCa1-xMnO3 (LCMO), a widely studied manganite, is known to substantially improve its transport properties when doped with Ag. However, despite the abundance of studies on LCMO, the effect of silver on the surface structure is unknown. Here, through in-situ methods, scanning tunneling microscopy (STM) is performed on La5/8Ca3/8MnO3 films grown by pulsed laser deposition. Films doped by silver, as confirmed by in-situ X-ray photoelectron spectroscopy (XPS), display large-scale reconstructions, interpreted as being of type ( 10 10)R18.4 , while films lacking silver display a ( 2 2)R45 reconstruction that may be associated with a surface charge-ordered state. It is posited that the possible cause of the varied reconstructions is due to a vacancy ordering on top of the existing ( 2 2)R45 reconstruction. These studies highlight the influence of Ag on the surface structure, and therefore a route towards modifying the surface properties of manganites.

  11. Molecular phylogenetics at the Felsenstein zone: approaching the Strepsiptera problem using 5.8S and 28S rDNA sequences.

    PubMed

    Hwang, U W; Kim, W; Tautz, D; Friedrich, M

    1998-06-01

    Recent efforts to reconstruct the phylogenetic position of the insect order Strepsiptera have elicited a major controversy in molecular phylogenetics. We sequenced the 5.8S rDNA and major parts of the 28S rDNA 5' region of the strepsipteran species Stylops melittae. Their evolutionary dynamics were analyzed together with previously published insect rDNA sequences to identify tree estimation bias risks and to explore additional sources of phylogenetic information. Several major secondary structure changes were found as being autapomorphic for the Diptera, the Strepsiptera, or the Archaeognatha. Besides elevated substitution rates a significant AT bias was present in dipteran and strepsipteran 28S rDNA which, however, was restricted to stem sites in the Diptera while also affecting single-stranded sites in the Strepsiptera. When dipteran taxa were excluded from tree estimation all methods consistently supported the placement of Strepsiptera to within the Holometabola. When dipteran taxa were included maximum likelihood continued to favor a sister-group relationship of Strepsiptera with Mecoptera while remaining methods strongly supported a sister-group relationship with Diptera. Parametric bootstrap analysis revealed maximum likelihood as a consistent estimator if rate heterogeneity across sites was taken into account. Though the position of Strepsiptera within Holometabola remains elusive, we conclude that the evolution of dipteran and strepsipteran rDNA involved similar yet independent changes of substitution parameters. PMID:9667995

  12. Fabrication of Very High Efficiency 5.8 GHz Power Amplifiers using AlGaN HFETs on SiC Substrates for Wireless Power Transmission

    NASA Technical Reports Server (NTRS)

    Sullivan, Gerry

    2001-01-01

    For wireless power transmission using microwave energy, very efficient conversion of the DC power into microwave power is extremely important. Class E amplifiers have the attractive feature that they can, in theory, be 100% efficient at converting, DC power to RF power. Aluminum gallium nitride (AlGaN) semiconductor material has many advantageous properties, relative to silicon (Si), gallium arsenide (GaAs), and silicon carbide (SiC), such as a much larger bandgap, and the ability to form AlGaN/GaN heterojunctions. The large bandgap of AlGaN also allows for device operation at higher temperatures than could be tolerated by a smaller bandgap transistor. This could reduce the cooling requirements. While it is unlikely that the AlGaN transistors in a 5.8 GHz class E amplifier can operate efficiently at temperatures in excess of 300 or 400 C, AlGaN based amplifiers could operate at temperatures that are higher than a GaAs or Si based amplifier could tolerate. Under this program, AlGaN microwave power HFETs have been fabricated and characterized. Hybrid class E amplifiers were designed and modeled. Unfortunately, within the time frame of this program, good quality HFETs were not available from either the RSC laboratories or commercially, and so the class E amplifiers were not constructed.

  13. The influence of maternal self-objectification, materialism and parenting style on potentially sexualized 'grown up' behaviours and appearance concerns in 5-8year old girls.

    PubMed

    Slater, Amy; Tiggemann, Marika

    2016-08-01

    There is widespread concern about young girls displaying 'grown up' or sexualized behaviours, as well as experiencing body image and appearance concerns that were previously thought to only impact much older girls. The present study examined the influence of three maternal attributes, self-objectification, materialism and parenting style, on sexualized behaviours and appearance concerns in young girls. A sample of 252 Australian mothers of 5-8year old girls reported on the behaviours and appearance concerns observed in their daughters and also completed measures of their own self-objectification, materialism and parenting style. It was found that a significant proportion of young girls were engaging with 'teen' culture, using beauty products and expressing some degree of appearance concern. Maternal self-objectification was related to daughters' engagement in teen culture, use of beauty products and appearance concern. Maternal materialism was related to girls' engagement in teen culture and appearance concern, while an authoritative parenting style was negatively related to girls' use of beauty products. The findings suggest that maternal self-objectification and materialism play a role in the body image and appearance concerns of young girls, and in so doing, identify these maternal attributes as novel potential targets for intervention. PMID:27203569

  14. Effects of the A-site cation number on the properties of Ln5/8M3/8MnO 3 manganites

    NASA Astrophysics Data System (ADS)

    Collado, J. A.; García-Muñoz, J. L.; Aranda, M. A. G.

    2010-05-01

    The properties of manganites can be tuned by changing the doping level x in Ln1-xM xMnO 3. A second mechanism allows tuning of magnetic and electronic properties, for fixed x values, by varying the average A-cation radius, < r A>. Moreover, for fixed x and < r A> values, the changes in the A-cation size variance, σ2, also modify the ferromagnetic and metal-insulator transition temperatures. Here, we investigate the influence of the number of A-site cations on Ln5/8M3/8MnO 3 manganites, where x, < r A> and σ2 values are kept constant, and in the absence of phase separation phenomena. We have found that the number of cation species at the A site ( N A) has a strong influence on the width of the ferromagnetic and metal-insulator transitions, and a small influence on the average transition temperature. This behavior is opposite to that observed for increasing values of the variance σ2 in manganites, with the same x and < r A> values, where average transition temperatures are strongly reduced.

  15. Molecular confirmation of Trichomonas gallinae and other parabasalids from Brazil using the 5.8S and ITS-1 rRNA regions.

    PubMed

    Ecco, Roselene; Preis, Ingred S; Vilela, Daniel A R; Luppi, Marcela M; Malta, Marcelo C C; Beckstead, Robert B; Stimmelmayr, Raphaela; Stimmelmayer, Raphaela; Gerhold, Richard W

    2012-11-23

    Clinical, gross, and histopathology lesions and molecular characterization of Trichomonas spp. infection were described in two striped owls (Asio (Rhinoptynx) clamator), one American kestrel (Falco sparverius), two green-winged saltators (Saltator similis), and in a toco toucan (Ramphastos toco) from Brazil. These birds presented clinical signs including emaciation, ruffled feathers, abundant salivation and open mouth breathing presumably due to abundant caseous material. Gross lesions were characterized by multifocal yellow friable plaques on the surface of the tongue, pharynx and/or caseous masses partially occluding the laryngeal entrance. In the owls, the caseous material extended into the mandibular muscles and invaded the sinuses of the skull. Histopathologically, marked necrotic and inflammatory lesions were associated with numerous round to oval, pale eosinophilic structures (6-10μm) with basophilic nuclei, consistent with trichomonads. Organisms similar to those described above also were found in the liver of the two green-winged saltators. To the authors' knowledge, this is the first report of trichomonosis in a striped owl and a toco toucan. Sequence analysis of the Trichomonas spp. internal transcribed spacer 1 (ITS-1) region and partial 5.8S of the ribosomal RNA (rRNA) disclosed significant genetic diversity. Two sequences had 100% identity to Trichomonas gallinae, whereas two sequences had a 99% and 92% identity to a Trichomonas vaginalis-like sequence, respectively. One sequence (green-winged saltator 502-08) had a 100% identity to a newly recognized genus Simplicomonas. PMID:22749289

  16. The influence of maternal self-objectification, materialism and parenting style on potentially sexualized 'grown up' behaviours and appearance concerns in 5-8year old girls.

    PubMed

    Slater, Amy; Tiggemann, Marika

    2016-08-01

    There is widespread concern about young girls displaying 'grown up' or sexualized behaviours, as well as experiencing body image and appearance concerns that were previously thought to only impact much older girls. The present study examined the influence of three maternal attributes, self-objectification, materialism and parenting style, on sexualized behaviours and appearance concerns in young girls. A sample of 252 Australian mothers of 5-8year old girls reported on the behaviours and appearance concerns observed in their daughters and also completed measures of their own self-objectification, materialism and parenting style. It was found that a significant proportion of young girls were engaging with 'teen' culture, using beauty products and expressing some degree of appearance concern. Maternal self-objectification was related to daughters' engagement in teen culture, use of beauty products and appearance concern. Maternal materialism was related to girls' engagement in teen culture and appearance concern, while an authoritative parenting style was negatively related to girls' use of beauty products. The findings suggest that maternal self-objectification and materialism play a role in the body image and appearance concerns of young girls, and in so doing, identify these maternal attributes as novel potential targets for intervention.

  17. Genetic diversity of Histoplasma and Sporothrix complexes based on sequences of their ITS1-5.8S-ITS2 regions from the BOLD System.

    PubMed

    Estrada-Bárcenas, Daniel Alfonso; Vite-Garín, Tania; Navarro-Barranco, Hortensia; de la Torre-Arciniega, Raúl; Pérez-Mejía, Amelia; Rodríguez-Arellanes, Gabriela; Ramirez, Jose Antonio; Humberto Sahaza, Jorge; Taylor, Maria Lucia; Toriello, Conchita

    2014-01-01

    High sensitivity and specificity of molecular biology techniques have proven usefulness for the detection, identification and typing of different pathogens. The ITS (Internal Transcribed Spacer) regions of the ribosomal DNA are highly conserved non-coding regions, and have been widely used in different studies including the determination of the genetic diversity of human fungal pathogens. This article wants to contribute to the understanding of the intra- and interspecific genetic diversity of isolates of the Histoplasma capsulatum and Sporothrix schenckii species complexes by an analysis of the available sequences of the ITS regions from different sequence databases. ITS1-5.8S-ITS2 sequences of each fungus, either deposited in GenBank, or from our research groups (registered in the Fungi Barcode of Life Database), were analyzed using the maximum likelihood (ML) method. ML analysis of the ITS sequences discriminated isolates from distant geographic origins and particular wild hosts, depending on the fungal species analyzed. This manuscript is part of the series of works presented at the "V International Workshop: Molecular genetic approaches to the study of human pathogenic fungi" (Oaxaca, Mexico, 2012). PMID:24270072

  18. Making the Connection between Environmental Science and Decision Making

    NASA Astrophysics Data System (ADS)

    Woodhouse, C. A.; Crimmins, M.; Ferguson, D. B.; Garfin, G. M.; Scott, C. A.

    2011-12-01

    As society is confronted with population growth, limited resources, and the impacts of climate variability and change, it is vital that institutions of higher education promote the development of professionals who can work with decision-makers to incorporate scientific information into environmental planning and management. Skills for the communication of science are essential, but equally important is the ability to understand decision-making contexts and engage with resource managers and policy makers. It is increasingly being recognized that people who understand the linkages between science and decision making are crucial if science is to better support planning and policy. A new graduate-level seminar, "Making the Connection between Environmental Science and Decision Making," is a core course for a new post-baccalaureate certificate program, Connecting Environmental Science and Decision Making at the University of Arizona. The goal of the course is to provide students with a basic understanding of the dynamics between scientists and decision makers that result in scientific information being incorporated into environmental planning, policy, and management decisions. Through readings from the environmental and social sciences, policy, and planning literature, the course explores concepts including scientific information supply and demand, boundary organizations, co-production of knowledge, platforms for engagement, and knowledge networks. Visiting speakers help students understand some of the challenges of incorporating scientific information into planning and decision making within institutional and political contexts. The course also includes practical aspects of two-way communication via written, oral, and graphical presentations as well as through the interview process to facilitate the transfer of scientific information to decision makers as well as to broader audiences. We aspire to help students develop techniques that improve communication and

  19. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (84th, Washington, DC, August 5-8, 2001). Public Relations Division.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Public Relations section of the proceedings contains the following 11 selected papers: "If We Build It, Will They Come? Testing the Theory of Planned Behavior as a Predictive Model for Use in Determining How Career Counseling Centers Can Better Promote Their Facilities and Services" (Carolyn Ringer Lepre); "Student Preferences for University…

  20. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (81st, Baltimore, Maryland, August 5-8, 1988). Public Relations.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Public Relations section of the Proceedings contains the following 15 papers: "The World Wide Web as a Public Relations Medium: The Use of Research, Planning, and Evaluation by Web Site Decision-Makers" (Candace White and Niranjan Raman); "Enlightened Self Interest--An Ethical Baseline for Teaching Corporate Public Relations" (Patricia T.…

  1. Long Range Planning: A Key to Effective Management.

    ERIC Educational Resources Information Center

    Pillinger, Barbara Baxter; Kraack, Thomas A.

    1981-01-01

    Presents a long-range planning model developed from varied approaches to planning and decision making. The model outlines categories representing planning needs and specifies objectives for each category. Categories are also matched with planning agencies. (RC)

  2. Airborne geophysical surveys used to delineate geological features associated with the M5.8 August 23, 2011 earthquake in Louisa County, Virginia

    NASA Astrophysics Data System (ADS)

    Shah, A. K.; Horton, J. W.; Gilmer, A. K.

    2012-12-01

    The M5.8 August 23, 2011 Louisa County, VA intraplate earthquake was felt by more people than any other in U.S. history not only because of population density, but also because of the associated geology. However, because limited bedrock exposures pose a challenge to geologic mapping efforts and the earthquake hypocenter is located at a depth of ~6 km, many questions remain. Potential field and gamma-ray spectrometry data thus provide key tools for imaging and understanding both shallow and deep subsurface geologic features. In July 2012, the USGS commissioned a high-resolution magnetic, gravity, and radiometric (gamma-ray spectrometry) survey over a 20 km x 25 km area covering the epicenters of the Louisa County earthquake and its aftershocks. The surveys were flown with 200-m line spacing from an altitude of ~120 m above ground, providing up to a 20-fold improvement over regional magnetic and radiometric coverage. Gravity was measured using Sander Geophysics' AIRGrav system, capable of resolving anomalies as narrow as 800 m for the given survey configuration; in most parts of the survey area the spacing of ground stations is ~10-20 stations per 100 km2. Preliminary magnetic and radiometric data show numerous NE-trending linear anomalies within this part of the Appalachian Piedmont Province. These metamorphic and igneous rocks exhibit 200-500 nT magnetic anomalies of width 300-1000 km that are likely to be generated by contrasts between various metavolcanic and metasedimentary rocks such as magnetite-bearing quartzites and felsic to mafic gneisses. Magnetic lows and radiometric highs are observed over several granitoid intrusive bodies such as the Ellisville pluton, the Falmouth Intrusive Suite, and a Paleozoic pegmatite belt. Derivative magnetic maps delineate numerous thin (< 250 m wide) N- NNW-trending linear anomalies, suggesting that Jurassic diabase dikes are much more common in this area than previously mapped. Radiometric data mostly correlate with mapped

  3. The Puerto Rico 5.8 MW Earthquake of May 16, 2010, and the Distribution of Peak Ground Motion in the Puerto Rico Island

    NASA Astrophysics Data System (ADS)

    Huerta-Lopez, C. I.; Martínez-Cruzado, J. A.; Suarez, L. E.; López, R. R.; Caro-Cortes, J. A.; Upegui-Botero, F. M.; Ramirez-Gaytan, G. A.

    2010-12-01

    On may 16, 2010 a 5.8 MW earthquake occurred in the northwest region of Puerto Rico Island (18.4o Lat., -67.07o Lon., and focal depth 113.1 km) at 05:16:10 UTC, reporting an intensity of VI in the city of Añasco, which is located at approximately at 15 km from its epicenter, while in some cases the intensity hardly reach an intensity of III in towns located at closer epicentral distances. This earthquake was widely felt in Puerto Rico, the eastern Dominican Republic, and The Virgin Islands. It was recorded also by 59 stations of the Puerto Rico Strong Motion Program (PRSMP) providing a reliable set of acceleration records distributed around the island. According to the USGS Centroid Moment Tensor solution, this earthquake occurred in an inclined seismic zone that dips south from the Puerto Rico Trench and that consists of subducted lithosphere of the North America plate. Earthquakes that have focal-depths between 70 and 300 km, are commonly termed "intermediate-depth" earthquakes and typically cause less damage on the ground surface above their foci than is the case with similar magnitude shallow-focus earthquakes. Large intermediate-depth earthquakes may be felt at great distance from their epicenters. In terms of the observed maximum peak ground acceleration it was: (i) 0.0651 of g at Añasco (AÑS1 station, located at an epicentral distance of 15 km in alluvial soil), and (ii) 0.2301 of g at station UTD2 located at an epicentral distance of 42 km on rock. The instrumental intensity (MMI) estimated with Wald et al., (1999) relationship was V and VII, respectively for these two previously described sites. An analysis and discussion is presented with the aim to explain the anomalous distribution of peak ground motions, which may be associated not only by local site effects due to the presence of soft soils.

  4. ZO-1 regulates Erk, Smad1/5/8, Smad2, and RhoA activities to modulate self-renewal and differentiation of mouse embryonic stem cells.

    PubMed

    Xu, Jianliang; Lim, Sophia Beng Hui; Ng, Mei Yong; Ali, Safiah Mohamed; Kausalya, Jaya P; Limviphuvadh, Vachiranee; Maurer-Stroh, Sebastian; Hunziker, Walter

    2012-09-01

    ZO-1/Tjp1 is a cytosolic adaptor that links tight junction (TJ) transmembrane proteins to the actin cytoskeleton and has also been implicated in regulating cell proliferation and differentiation by interacting with transcriptional regulators and signaling proteins. To explore possible roles for ZO-1 in mouse embryonic stem cells (mESCs), we inactivated the ZO-1 locus by homologous recombination. The lack of ZO-1 was found to affect mESC self-renewal and differentiation in the presence of leukemia-inhibiting factor (LIF) and Bmp4 or following removal of the growth factors. Our data suggest that ZO-1 suppresses Stat3 and Smad1/5/8 activities and sustains extracellular-signal-regulated kinase (Erk) activity to promote mESC differentiation. Interestingly, Smad2, critical for human but not mESC self-renewal, was hyperactivated in ZO-1(-/-) mESCs and RhoA protein levels were concomitantly enhanced, suggesting attenuation of the noncanonical transforming growth factor β (Tgfβ)/Activin/Nodal pathway that mediates ubiquitination and degradation of RhoA via the TJ proteins Occludin, Par6, and Smurf1 and activation of the canonical Smad2-dependent pathway. Furthermore, Bmp4-induced differentiation of mESCs in the absence of LIF was suppressed in ZO-1(-/-) mESCs, but differentiation down the neural or cardiac lineages was not disturbed. These findings reveal novel roles for ZO-1 in mESC self-renewal, pluripotency, and differentiation by influencing several signaling networks that regulate these processes. Possible implications for the differing relevance of Smad2 in mESC and human ESC self-renewal and how ZO-1 may connect to the different pathways are discussed.

  5. Structure and Properties of Ti-19.7Nb-5.8Ta Shape Memory Alloy Subjected to Thermomechanical Processing Including Aging

    NASA Astrophysics Data System (ADS)

    Dubinskiy, S.; Brailovski, Vladimir; Prokoshkin, S.; Pushin, V.; Inaekyan, K.; Sheremetyev, V.; Petrzhik, M.; Filonov, M.

    2013-09-01

    In this work, the ternary Ti-19.7Nb-5.8Ta (at.%) alloy for biomedical applications was studied. The ingot was manufactured by vacuum arc melting with a consumable electrode and then subjected to hot forging. Specimens were cut from the ingot and processed by cold rolling with e = 0.37 of logarithmic thickness reduction and post-deformation annealing (PDA) between 400 and 750 °C (1 h). Selected samples were subjected to aging at 300 °C (10 min to 3 h). The influence of the thermomechanical processing on the alloy's structure, phase composition, and mechanical and functional properties was studied. It was shown that thermomechanical processing leads to the formation of a nanosubgrained structure (polygonized with subgrains below 100 nm) in the 500-600 °C PDA range, which transforms to a recrystallized structure of β-phase when PDA temperature increases. Simultaneously, the phase composition and the β → α″ transformation kinetics vary. It was found that after conventional cold rolling and PDA, Ti-Nb-Ta alloy manifests superelastic and shape memory behaviors. During aging at 300 °C (1 h), an important quantity of randomly scattered equiaxed ω-precipitates forms, which results in improved superelastic cyclic properties. On the other hand, aging at 300 °C (3 h) changes the ω-precipitates' particle morphology from equiaxed to elongated and leads to their coarsening, which negatively affects the superelastic and shape memory functional properties of Ti-Nb-Ta alloy.

  6. Transmission Planning Analysis Tool

    SciTech Connect

    2015-06-23

    Developed to solve specific problem: Assist transmission planning for regional transfers in interconnected power systems. This work was originated in a study for the U.S. Department of State, to recommend transmission reinforcements for the Central American regional system that interconnects 6 countries. Transmission planning analysis is currently performed by engineers with domainspecific and systemspecific knowledge without a unique methodology. The software codes of this disclosure assists engineers by defining systematic analysis procedures to help identify weak points and make decisions on transmission planning of regional interconnected power systems. Transmission Planning Analysis Tool groups PSS/E results of multiple AC contingency analysis and voltage stability analysis and QV analysis of many scenarios of study and arrange them in a systematic way to aid power system planning engineers or transmission operators in effective decision]making process or in the off]line study environment.

  7. Transmission Planning Analysis Tool

    2015-06-23

    Developed to solve specific problem: Assist transmission planning for regional transfers in interconnected power systems. This work was originated in a study for the U.S. Department of State, to recommend transmission reinforcements for the Central American regional system that interconnects 6 countries. Transmission planning analysis is currently performed by engineers with domainspecific and systemspecific knowledge without a unique methodology. The software codes of this disclosure assists engineers by defining systematic analysis procedures to help identifymore » weak points and make decisions on transmission planning of regional interconnected power systems. Transmission Planning Analysis Tool groups PSS/E results of multiple AC contingency analysis and voltage stability analysis and QV analysis of many scenarios of study and arrange them in a systematic way to aid power system planning engineers or transmission operators in effective decision]making process or in the off]line study environment.« less

  8. Halley's Comet Makes a Comeback.

    ERIC Educational Resources Information Center

    Glenn, William H.

    1984-01-01

    Presents information on Halley's Comet including its discovery, impact on history, planned investigations related to its 1986 return, where and when to make observations, and predicted calendar of events. Gives general information on comets such as physical structure, theoretical origin, and paths and provides an annotated reference list. (JM)

  9. A Plan for All Seasons.

    ERIC Educational Resources Information Center

    Golden, Sandra

    1993-01-01

    Planning can help college public relations officials make the most of their time and energy. One approach includes reviewing institutional mission and strategic plan; setting department goals; identifying and targeting audiences; establishing interdepartmental links; and setting out action, crisis, budget, and evaluation plans in writing. (MSE)

  10. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (85th, Miami, Florida, August 5-8, 2002). Minorities and Communication Division.

    ERIC Educational Resources Information Center

    2002

    The Minorities and Communication Division of the proceedings contains the following 7 papers: "The Race Card and Ethical Reasoning: The Importance of Race to Journalistic Decision Making" (Renita Coleman); "Jesse Owens, A Black Pearl Amidst an Ocean of Fury: A Case Study of Press Coverage on The 1936 Berlin Olympic Games" (Pamela C. Laucella); "A…

  11. Magnetic, gravity, radiometric, LiDAR, and seismic data to characterize the region of the M5.8 August 23, 2011 earthquake near Mineral, Virginia

    NASA Astrophysics Data System (ADS)

    Shah, A. K.; McNamara, D. E.; Odum, J. K.; Stephenson, W. J.; Kayen, R. E.; Emmett, P. F.; Herrmann, R. B.; Snyder, S. L.; Horton, J. W.; Williams, R. A.

    2012-12-01

    In response to the M5.8 August 23, 2011 Mineral, VA earthquake, the U.S. Geological Survey and partner organizations acquired or sponsored collection of several geophysical datasets to assist characterization of the earthquake region. Goals include the mapping of the main shock causative and aftershock faults as well as associated geologic features which may be buried or difficult to access, estimates of regional ground motion attenuation, and measurements describing local amplification of seismic energy. The deployment of 46 portable seismic stations by several organizations within days following the earthquake, along with public availability of the resulting data, has greatly aided site characterization efforts. The aftershock data recorded by these stations have allowed delineation of the probable causative fault and other faults that were active afterwards. Using the portable seismograph network and regional permanent stations, S and Lg waves were analyzed to estimate crustal attenuation characteristics. Active- and passive-source seismic experiments were also conducted at many of the portable and permanent stations to characterize site conditions and constrain local response models via estimates of Vs30 and bedrock depth. In March 2012, a LiDAR survey with 8pt/m2 resolution was flown over a ~20x35 km area covering the epicenters of the earthquake and most aftershocks. In July 2012, a high-resolution airborne magnetic, gravity, and radiometric survey was flown over a similar but slightly smaller area. Supplementary ground gravity data have been collected inside and outside of the airborne survey areas. The gravity and magnetic data reflect subsurface features in a region where outcropping rocks are sparse, while LiDAR and radiometric data, respectively, delineate subtle features at the land surface and upper few centimeters. Each of these datasets reflects the regional NE-SW striking fabric. Seismic wave analyses show preferential attenuation in a NW

  12. Closure of the Indonesian Seaway during the middle to late Miocene (13.2-5.8 Ma): Early history of the Western Pacific Warm Pool

    NASA Astrophysics Data System (ADS)

    Leckie, R.; Nathan, S. A.

    2007-12-01

    We document the waxing and waning of a 'proto-Western Pacific Warm Pool' and Equatorial Undercurrent (EUC) based on a study of multi-species planktic foraminiferal isotope ratios and census data spanning the 13.2-5.8 Ma interval at ODP Site 806 in the western equatorial Pacific (WEP). We hypothesize that the presence or absence of a proto-warm pool in the WEP, caused by the progressive tectonic constriction of the Indonesian Seaway and modulated by sea level fluctuations, created El Ni~{n}o/La Ni~{n}a-like alternations of hydrographic conditions across the equatorial Pacific during the late Miocene. This hypothesis is supported by the general antithetical relationship observed between carbonate productivity and preservation in the western and eastern equatorial Pacific, a phenomenon caused by these alternating ocean-climate states in the modern ocean. The two-step development and intensification of a proto-warm pool 11.6-9.6 Ma coincides with ice sheet expansion associated with Miocene isotope events Mi5 and Mi6, resulting in a cumulative sea level fall of 50 m and production of Northern Component Water. It also marks the initiation of a more modern equatorial current system as La Ni~{n}a-like conditions became established across the tropical Pacific. This situation sustained carbonate and silica productivity in the eastern equatorial Pacific (EEP) at a time when carbonate preservation sharply declined in the Caribbean. Proto-warm pool weakening after 10 Ma may have contributed to the nadir of a similar 'carbonate crash' in the EEP. Decay of the proto-warm pool and resultant El Ni~{n}o-like conditions brought higher productivity to the WEP, particularly 9.0-8.8 Ma coincident with a major perturbation in tropical nannofossil assemblages. This interval of increased productivity records the initial phase of the widespread 'biogenic bloom'. Resurgence of a later proto-warm pool in the WEP 6.5-6.1 Ma may have spurred renewed La Ni~{n}a-like conditions, which contributed

  13. MSG/SEVIRI, NOAA/AVHRR and EOS/MODIS TIR observations during the Abruzzo 6 April 2009 earthquake (ML~ 5.8)

    NASA Astrophysics Data System (ADS)

    Genzano, Nicola; Corrado, Rosita; Filizzola, Carolina; Lacava, Teodosio; Lisi, Mariano; Marchese, Francesco; Mazzeo, Giuseppe; Paciello, Rossana; Pergola, Nicola; Tramutoli, Valerio

    2010-05-01

    Space-time fluctuations of Earth's emitted Thermal Infrared (TIR) radiation have been observed from satellite months to weeks before earthquakes occurrence. Different authors, in order to explain the appearance of anomalously high TIR records near the place and the time of earthquake occurrence, attributed their appearance to the increase of green-house gas (such as CO2, CH4, etc.) emission rates, to the modification of ground water regime and/or to the increase of convective heat flux. In this contest, an approach called Robust Satellite Techniques (RST) has been proposed in order to discriminate normal (i.e. related to the change of natural factor and/or observation conditions) TIR signal fluctuations from anomalous signal transient possibly associated to earthquake occurrence. In the past RST was already tested in the case of tens of earthquakes with a wide range of magnitudes (from 4.0 to 7.9) occurred in different continents and in various geo-tectonic setting (e.g. 1980 Irpinia-Basilicata earthquake; Izmit earthquake, 17 August 1999; Hector Mine earthquake, 16 October 1999, etc.). The RST analysis is based on a statistically definition of "TIR anomalies" and a suitable method for their identification even in very different local (e.g. related to atmosphere and/or surface) and observational (e.g. related to time/season, but also to solar and satellite zenithal angles) conditions, and has been always carried out by using a validation/confutation approach, to verify the presence/absence of anomalous space-time TIR transients in the presence/absence of seismic activity. In this work the same approach is applied to the case of Abruzzo 6 April 2009 event (ML=5.8) and compared with an identical analysis (confutation) performed in seismically unperturbed years. RST analysis was performed on a historical data set made of 30 years of contemporary observations done by 3 independent satellite systems (5 years of MSG/SEVIRI, 15 years of NOAA/AVHRR and 10 years of EOS

  14. Middle-Management Participatory Decision Making.

    ERIC Educational Resources Information Center

    Goss, Theresa C.

    1984-01-01

    Explores areas of middle management in which community/junior college librarians could be more involved and productive (e.g., planning, coordination, and public relations). Offers guidelines for effective group decision making. (DMM)

  15. Guidelines for Planning in Colleges and Universities. Volume One, Planning System.

    ERIC Educational Resources Information Center

    Pinnell, Charles; Wacholder, Michael

    This volume outlines a system for effective planning in higher education. The system integrates management and program planning, physical plant planning, and financial planning into a single process designed to support institutional management and decision making at all administrative levels. Because successful planning is a process, procedures…

  16. Language Planning: Corpus Planning.

    ERIC Educational Resources Information Center

    Baldauf, Richard B., Jr.

    1989-01-01

    Focuses on the historical and sociolinguistic studies that illuminate corpus planning processes. These processes are broken down and discussed under two categories: those related to the establishment of norms, referred to as codification, and those related to the extension of the linguistic functions of language, referred to as elaboration. (60…

  17. 46 CFR 185.503 - Voyage plan.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Voyage plan. 185.503 Section 185.503 Shipping COAST...) OPERATIONS Preparations for Emergencies § 185.503 Voyage plan. (a) The master of the following vessels shall prepare a voyage plan: (1) A vessel making an oceans or coastwise voyage; (2) A vessel making a voyage...

  18. Making It All Work: The Balancing Act

    ERIC Educational Resources Information Center

    Schaefbauer, Christi

    2013-01-01

    In this brief article, the author shares some strategies that make her work and home life easier and more gratifying: (1) Declutter and simplify; (2) Plan meals; (3) Use Google Calendar; (4) Automate bills; (5) Use technology; (6) Make health a priority; and (7) Lose the guilt.

  19. Sex and Career Decision-Making Styles.

    ERIC Educational Resources Information Center

    Lunneborg, Patricia W.

    1978-01-01

    Tested the hypothesis of greater reliance on the intuitive style by females and on the planning style by males in making career decisions. There were no sex differences in these high school and college samples for stage or style of decision making, vocational self-concept crystallization, or self-rated vocational decisiveness. (Author/BEF)

  20. Make a Difference! Elementary Service Projects.

    ERIC Educational Resources Information Center

    Wolfenbarger, Beth; Turner, Suzanne; Lerner, Debbie; Sloyer, Beth; Comstock, Jan; Unruh, Judy; Selle, Penny; Tarpley, Linda; Alford, Leslie; Frank, Patty; Hall, Teresa; Windes, Mike

    2000-01-01

    Describes how Red Bridge Elementary (Kansas City, Missouri) participated in the "Reduce, Reuse, and Recycle--Make a Difference in Our Community" campaign that coincided with the 1998 Make a Difference Day Campaign. Discusses the project, including the planning, publicity, donation collection, donation distribution, and campaign results. (CMK)

  1. Analytic Planning in Education: Critical Perspectives

    ERIC Educational Resources Information Center

    Nevas, Susan R.

    1977-01-01

    The author discusses the use of planning-programming-budgeting systems (PBBS) in educational planning, decision-making, and control, and suggests ways in which its applicability and effectiveness may be broadened. (MJB)

  2. Automatic planning of head and neck treatment plans.

    PubMed

    Hazell, Irene; Bzdusek, Karl; Kumar, Prashant; Hansen, Christian R; Bertelsen, Anders; Eriksen, Jesper G; Johansen, Jørgen; Brink, Carsten

    2016-01-01

    Treatment planning is time-consuming and the outcome depends on the person performing the optimization. A system that automates treatment planning could potentially reduce the manual time required for optimization and could also provide a method to reduce the variation between persons performing radiation dose planning (dosimetrist) and potentially improve the overall plan quality. This study evaluates the performance of the Auto-Planning module that has recently become clinically available in the Pinnacle3 radiation therapy treatment planning system. Twenty-six clinically delivered head and neck treatment plans were reoptimized with the Auto-Planning module. Comparison of the two types of treatment plans were performed using DVH metrics and a blinded clinical evaluation by two senior radiation oncologists using a scale from one to six. Both evaluations investigated dose coverage of target and dose to healthy tissues. Auto-Planning was able to produce clinically acceptable treatment plans in all 26 cases. Target coverages in the two types of plans were similar, but automatically generated plans had less irradiation of healthy tissue. In 94% of the evaluations, the autoplans scored at least as high as the previously delivered clinical plans. For all patients, the Auto-Planning tool produced clinically acceptable head and neck treatment plans without any manual intervention, except for the initial target and OAR delineations. The main benefit of the method is the likely improvement in the overall treatment quality since consistent, high-quality plans are generated which even can be further optimized, if necessary. This makes it possible for the dosimetrist to focus more time on difficult dose planning goals and to spend less time on the more tedious parts of the planning process.

  3. Learning To Live Together: Have We Failed? A Summary of the Ideas and Contributions Arising from the Forty-Sixth Session of UNESCO's International Conference on Education (Geneva, Switzerland, September 5-8, 2001).

    ERIC Educational Resources Information Center

    International Bureau of Education, Geneva (Switzerland).

    This book is based mainly on the work of the 46th session of the International Conference on Education (ICE), organized by the United Nations Educational, Scientific, and Cultural Organizations' International Bureau of Education (IBE) held in Geneva, Switzerland, September 5-8, 2001. The ICE is the only regularly occurring event during which…

  4. Working with Villagers. Media Resource Book: Skill Exercises, Line Drawings, Recipes for Making Teaching Tools and Materials. Activities, Media Skills, and Sample Lessons for Training Fieldworkers in Home Economics and Family Planning.

    ERIC Educational Resources Information Center

    Peace Corps, Washington, DC. Information Collection and Exchange Div.

    Designed for use in conducting media production training with Peace Corps fieldworkers, this manual is divided into three sections: skill exercises, line drawings, and directions for making art supplies from easily obtainable, low cost resources. Nineteen step-by-step skill exercises cover basic cutting, wet and dry mounting, simple drawing,…

  5. Why Planning Doesn't (Always) Fulfill Expectations.

    ERIC Educational Resources Information Center

    LeDuc, Albert L.

    1986-01-01

    Typical higher management expectations for the planning process are explored, along with why these expectations cannot always be met. Some limitations to planning for computer services are proposed that can make planning meaningful for operational concerns. (MLW)

  6. 42 CFR 441.252 - State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Sterilizations § 441.252 State plan requirements. A State plan must provide that the Medicaid agency will make payment under the plan for sterilization procedures and hysterectomies only if all the requirements...

  7. 5.8kV SiC PiN Diode for Switching of High-Efficiency Inductive Pulsed Plasma Thruster Circuits

    NASA Technical Reports Server (NTRS)

    Toftul, Alexandra; Polzin, Kurt A.; Hudgins, Jerry L.

    2014-01-01

    Inductive Pulsed Plasma Thruster (IPPT) pulse circuits, such as those needed to operate the Pulsed Inductive Thruster (PIT), are required to quickly switch capacitor banks operating at a period of µs while conducting current at levels on the order of at least 10 kA. [1,2] For all iterations of the PIT to date, spark gaps have been used to discharge the capacitor bank through an inductive coil. Recent availability of fast, high-power solid state switching devices makes it possible to consider the use of semiconductor switches in modern IPPTs. In addition, novel pre-ionization schemes have led to a reduction in discharge energy per pulse for electric thrusters of this type, relaxing the switching requirements for these thrusters. [3,4] Solid state switches offer the advantage of greater controllability and reliability, as well as decreased drive circuit dimensions and mass relative to spark gap switches. The use of solid state devices such as Integrated Gate Bipolar Transistors (IGBTs), Gate Turn-off Thyristors (GTOs) and Silicon-Controlled Rectifiers (SCRs) often involves the use of power diodes. These semiconductor devices may be connected antiparallel to the switch for protection from reverse current, or used to reduce power loss in a circuit by clamping off current ringing. In each case, higher circuit efficiency may be achieved by using a diode that is able to transition, or 'switch,' from the forward conducting state ('on' state) to the reverse blocking state ('off' state) in the shortest amount of time, thereby minimizing current ringing and switching losses. Silicon Carbide (SiC) PiN diodes offer significant advantages to conventional fast-switching Silicon (Si) diodes for high power and fast switching applications. A wider band gap results in a breakdown voltage 10 times that of Si, so that a SiC device may have a thinner drift region for a given blocking voltage. [5] This leads to smaller, lighter devices for high voltage applications, as well as reduced

  8. Making Meaningful: Intention in Children's Art Making

    ERIC Educational Resources Information Center

    Malin, Heather

    2013-01-01

    Children's art work has often been the subject of study by researchers seeking to gain insight into the role of art making in children's learning and development. However, rarely are children's own explanations of their art making used to inform these studies. Children's perceptions of their own art making are important for research and practice…

  9. Phylogenetic study of Baylisascaris schroederi isolated from Qinling subspecies of giant panda in China based on combined nuclear 5.8S and the second internal transcribed spacer (ITS-2) ribosomal DNA sequences.

    PubMed

    Zhao, Guang-Hui; Li, Hong-Mei; Ryan, Una M; Cong, Mei-Mei; Hu, Bing; Gao, Man; Ren, Wan-Xin; Wang, Xing-Ye; Zhang, Shui-Ping; Lin, Qing; Zhu, Xing-Quan; Yu, San-Ke

    2012-09-01

    The nuclear ribosomal DNA (rDNA) region spanning 5.8S rDNA and the second internal transcribed spacer (ITS-2) of Baylisascaris schroederi isolated from the Qinling subspecies of giant panda in Shaanxi Province, China were amplified and sequenced. Sequence variations in the two rDNA regions within B. schroederi and among species in the family Ascarididae were examined. The lengths of B. schroederi 5.8S and ITS-2 rDNA sequences were 156 bp and 327 bp, respectively, and no nucleotide variation was found in these two rDNA regions among the 20 B. schroederi samples examined, and these ITS-2 sequences were identical to that of B. schroederi isolated from giant panda in Sichuan province, China. The inter-species differences in 5.8S and ITS-2 rDNA sequences among members of the family Ascarididae were 0-1.3% and 0-17.7%, respectively. Phylogenetic relationships among species in the Ascarididae were re-constructed by Bayesian inference (Bayes), maximum parsimony (MP), and maximum likelihood (ML) analyses, based on combined sequences of 5.8S and ITS-2 rDNA. All B. schroederi samples clustered together and sistered to B. transfuga with high posterior probabilities/bootstrap values, which further confirmed that nematodes isolated from the Qinling subspecies of giant panda in Shaanxi Province, China represent B. schroederi. Because of the large number of ambiguously aligned sequence positions (difficulty of inferring homology by positions), ITS-2 sequence alone is likely unsuitable for phylogenetic analyses at the family level, but the combined 5.8S and ITS-2 rDNA sequences provide alternative genetic markers for the identification of B. schroederi and for phylogenetic analysis of parasites in the family Ascarididae.

  10. FAmily CEntered (FACE) advance care planning: Study design and methods for a patient-centered communication and decision-making intervention for patients with HIV/AIDS and their surrogate decision-makers

    PubMed Central

    Kimmel, Allison L.; Wang, Jichuan; Scott, Rachel; Briggs, Linda; Lyon, Maureen E.

    2016-01-01

    Although the Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) has become a chronic illness, disease-specific advance care planning has not yet been evaluated for the palliative care needs of adults with HIV/AIDS. This prospective, longitudinal, randomized, two-arm controlled clinical trial aims to test the efficacy of FAmily CEntered Advance Care Planning among adults living with AIDS and/or HIV with co-morbidities on congruence in treatment preferences, healthcare utilization, and quality of life. The FAmily CEntered intervention arm is two face-to-face sessions with a trained, certified facilitator: Session 1) Disease-Specific Advance Care Planning Respecting Choices Interview; Session 2) Completion of advance directive. The Healthy Living control arm is: Session 1) Developmental/Relationship History; Session 2) Nutrition. Follow-up data will be collected at 3, 6, 12, and 18-month post-intervention. A total of 288 patient/surrogate dyads will be enrolled from five hospital-based, out-patient clinics in Washington, District of Columbia. Participants will be HIV positive and ≥21 years of age; surrogates will be ≥18 years of age. Exclusion criteria are homicidality, suicidality, psychosis, and impaired cognitive functioning. We hypothesize that this intervention will enhance patient-centered communication with a surrogate decision-maker about end of life treatment preferences over time, enhance patient quality of life and decrease health care utilization. We further hypothesize that this intervention will decrease health disparities for Blacks in completion of advance directives. If proposed aims are achieved, the benefits of palliative care, particularly increased treatment preferences about end-of-life care and enhanced quality of life, will be extended to people living with AIDS. PMID:26044463

  11. FAmily CEntered (FACE) advance care planning: Study design and methods for a patient-centered communication and decision-making intervention for patients with HIV/AIDS and their surrogate decision-makers.

    PubMed

    Kimmel, Allison L; Wang, Jichuan; Scott, Rachel K; Briggs, Linda; Lyon, Maureen E

    2015-07-01

    Although the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has become a chronic illness, disease-specific advance care planning has not yet been evaluated for the palliative care needs of adults with HIV/AIDS. This prospective, longitudinal, randomized, two-arm controlled clinical trial aims to test the efficacy of FAmily CEntered advance care planning among adults living with AIDS and/or HIV with co-morbidities on congruence in treatment preferences, healthcare utilization, and quality of life. The FAmily CEntered intervention arm is two face-to-face sessions with a trained, certified facilitator: Session 1) Disease-Specific Advance Care Planning Respecting Choices Interview; Session 2) Completion of advance directive. The Healthy Living Control arm is: Session 1) Developmental/Relationship History; Session 2) Nutrition. Follow-up data will be collected at 3, 6, 12, and 18 months post-intervention. A total of 288 patient/surrogate dyads will be enrolled from five hospital-based, out-patient clinics in Washington, District of Columbia. Participants will be HIV positive and ≥ 21 years of age; surrogates will be ≥ 18 years of age. Exclusion criteria are homicidality, suicidality, psychosis, and impaired cognitive functioning. We hypothesize that this intervention will enhance patient-centered communication with a surrogate decision-maker about end of life treatment preferences over time, enhance patient quality of life and decrease health care utilization. We further hypothesize that this intervention will decrease health disparities for Blacks in completion of advance directives. If proposed aims are achieved, the benefits of palliative care, particularly increased treatment preferences about end-of-life care and enhanced quality of life, will be extended to people living with AIDS.

  12. Guidelines for strategic planning

    SciTech Connect

    Not Available

    1991-07-01

    Strategic planning needs to be done as one of the integral steps in fulfilling our overall Departmental mission. The role of strategic planning is to assure that the longer term destinations, goals, and objectives which the programs and activities of the Department are striving towards are the best we can envision today so that our courses can then be set to move in those directions. Strategic planning will assist the Secretary, Deputy Secretary, and Under Secretary in setting the long-term directions and policies for the Department and in making final decisions on near-term priorities and resource allocations. It will assist program developers and implementors by providing the necessary guidance for multi-year program plans and budgets. It is one of the essential steps in the secretary's Strategic Planning Initiative. The operational planning most of us are so familiar with deals with how to get things done and with the resources needed (people, money, facilities, time) to carry out tasks. Operating plans like budgets, capital line item projects, R D budgets, project proposals, etc., are vital to the mission of the Department. They deal, however, with how to carry out programs to achieve some objective or budget assumption. Strategic planning deals with the prior question of what it is that should be attempted. It deals with what objectives the many programs and activities of the Department of Department should be striving toward. The purpose of this document is to provide guidance to those organizations and personnel starting the process for the first time as well as those who have prepared strategic plans in the past and now wish to review and update them. This guideline should not be constructed as a rigid, restrictive or confining rulebook. Each organization is encouraged to develop such enhancements as they think may be useful in their planning. The steps outlined in this document represent a very simplified approach to strategic planning. 9 refs.

  13. PNNL Campus Master Plan

    SciTech Connect

    Mosey, Whitney LC

    2012-09-07

    The Plan is used as a guide for PNNL in making facility and infrastructure decisions essential to supporting the PNNL vision: to establish a modern, collaborative, flexible, and sustainable campus while optimizing the efficiency of operations in support of courageous discovery and innovation.

  14. Cooperative Science Lesson Plans.

    ERIC Educational Resources Information Center

    Cooperative Learning, 1991

    1991-01-01

    Offers several elementary level cooperative science lesson plans. The article includes a recipe for cooperative class learning, instructions for making a compost pile, directions for finding evidence of energy, experiments in math and science using oranges to test density, and discussions of buoyancy using eggs. (SM)

  15. Planned Programming Pays Dividends

    ERIC Educational Resources Information Center

    Geraldi, Kevin M.

    2008-01-01

    In this article, the author explains that before beginning to create concert programs, it is important that ensemble conductors first develop a long-term curricular plan to which each individual program will contribute. He continues that if an ensemble curriculum is devised so that students make progress over the long term, dynamic growth can take…

  16. Planning for Accessibility.

    ERIC Educational Resources Information Center

    Cassell, Marianne Kotch

    This practical manual provides useful, concrete ideas and suggestions to help public libraries make libraries more accessible to persons with disabilities. Most suggestions are for persons who have difficulty with mobility. Reviews of pertinent laws and regulations are followed by concrete, step-by step suggestions for planning for accessibility,…

  17. A Business Plan Outline.

    ERIC Educational Resources Information Center

    Kirchner, Charles, Ed.

    This document identifies the information that should be included in a business plan, and in what order, to make it an effective management tool and an effective tool to communicate a proposed or existing company's strengths and potential to potential financiers. Following an introduction, the document explains the following sections of a business…

  18. Data-Driven Planning: Using Assessment in Strategic Planning

    ERIC Educational Resources Information Center

    Bresciani, Marilee J.

    2010-01-01

    Data-driven planning or evidence-based decision making represents nothing new in its concept. For years, business leaders have claimed they have implemented planning informed by data that have been strategically and systematically gathered. Within higher education and student affairs, there may be less evidence of the actual practice of…

  19. Tough Times: Strategic Planning as a War Canoe

    ERIC Educational Resources Information Center

    Seymour, Daniel

    2011-01-01

    In this article, the author discusses how to make strategic planning a more valuable tool for higher education in today's tough times. Strategic planning is really the answer to five straightforward questions. The first three represent the plan itself, while the last two are what makes the plan vital and dynamic: (1) Why do we exist?; (2) What do…

  20. Planning Diseases.

    ERIC Educational Resources Information Center

    Gabel, Medard

    1984-01-01

    To solve societal problems, both local and global, a global approach is needed. Serious diseases that are crippling present-day problem solving and planning are discussed, and the characteristics of a healthy, effective planning approach are described. (RM)

  1. Planning and scheduling for success

    NASA Technical Reports Server (NTRS)

    Manzanera, Ignacio

    1994-01-01

    Planning and scheduling programs are excellent management tools when properly introduced to the project management team and regularly maintained. Communications, creativity, flexibility and accuracy are substantially improved by following a simple set of rules. A planning and scheduling program will work for you if you believe in it, make others in your project team realize its benefits, and make it an extension of your project cost control philosophy.

  2. Fire Plans

    ERIC Educational Resources Information Center

    Power, June

    2011-01-01

    Many libraries have disaster recovery plans, but not all have prevention and action plans to prepare for an emergency in advance. This article presents the author's review of the prevention and action plans of several libraries: (1) Evergreen State College; (2) Interlochen Public Library; (3) University of Maryland, Baltimore-Marshall Law Library;…

  3. Planned Giving for Catholic Schools.

    ERIC Educational Resources Information Center

    Bourbeau, Mary Ann

    Good development officers in elementary and high schools need to be aware of planned giving and knowledgeable about a variety of gift categories. Most school-development directors are not experts in this complex field. Yet, when a school decides to initiate a planned-giving program, the director of development must make a serious commitment to…

  4. Environmental Implementation Plan

    SciTech Connect

    Not Available

    1993-03-15

    The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site's environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognized model for Environmental Excellence in the Department of Energy's Nuclear Weapons Complex.

  5. Environmental Implementation Plan

    SciTech Connect

    Not Available

    1993-03-15

    The purpose of the Environmental Implementation Plan (EIP) is to show the current and future (five years) environmental plans from individual site organizations and divisions, as well as site environmental programs and initiatives which are designed to protect the environment and meet or exceed changing environmental/regulatory requirements. Communicating with site organizations, departments, and committees is essential in making the site`s environmental-planning process work. The EIP gives the site the what, when, how, and why for environmental requirements. Through teamwork and proactive planning, a partnership for environmental excellence is formed to achieve the site vision for SRS to become the recognized model for Environmental Excellence in the Department of Energy`s Nuclear Weapons Complex.

  6. Public Participation Plan

    SciTech Connect

    Not Available

    1993-07-01

    The purpose of this Public Participation Plan is to describe the US Department of Energy`s (DOE) plan for involving the public in the decision-making process for the Uranium Mill Tailings Remedial Action (UMTRA) Project. The plan describes how the DOE will meet the public participation requirements of the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, as amended, and of the National Environmental Policy Act (NEPA) of 1969. It includes the UMTRA Project Office plans for complying with DOE Order 5440.1D and for implementing the DOE`s Public Participation Policy for Environmental Restoration and Waste Management (1992) and Public Participation Guidance for Environmental Restoration and Waste Management (1993).

  7. Using plan reasoning in the generation of plan descriptions

    SciTech Connect

    Young, R.M.

    1996-12-31

    Previous work on the generation of natural language descriptions of complex activities has indicated that the unwieldy amount of text needed to describe complete plans makes for ineffective and unnatural descriptions. We argue here that concise and effective text descriptions of plans can be generated by exploiting a model of the hearer`s plan reasoning capabilities. We define a computational model of the hearer`s interpretation process that views the interpretation of plan descriptions as refinement search through a space of partial plans. This model takes into account the hearer`s plan preferences and the resource limitations on her reasoning capabilities to determine the completed plans she will construct from a given partial description.

  8. The Sellafield Plan - 12458

    SciTech Connect

    Irving, Iain

    2012-07-01

    The Sellafield Performance Plan represents the start of a new era for the Sellafield site. It is a key driver in the Nuclear Management Partners mission to make Sellafield safer, cleaner, more productive, more cost effective and a better neighbour. When published in summer 2011, the Sellafield Performance Plan set out exactly what work would be completed at Sellafield between 2010/11 and 2025/26, how all of the facilities on the site interact, and what new facilities would be needed in order to deliver the risk and hazard reduction mission. The plan is the first credible and underpinned lifetime plan for the Sellafield site - the most complex part of the UK's civil nuclear estate. Under the Sellafield Performance Plan there are projected to be more jobs longer creating opportunities for the site, its workforce and the economic stability of West Cumbria. The Sellafield Ltd performance plan sets out how NMP will apply their global experience to improve operations, generate efficiencies and deliver detailed programmes of work with the aim of accelerating decommissioning and providing value for money. Successful delivery of the plan will also ensure the site continues to effectively operate critical national infrastructure that supports the UK's energy programme, and maintains the safe and secure management and storage of nuclear materials. The NDA and UK Government have demonstrated their confidence in NMP and Sellafield Ltd's capability to deliver this plan by providing the highest-ever Annual Site Funding Limit for the site in 2011/12. The Sellafield Performance Plan also creates both the foundation and the environment for a vibrant West Cumbrian economy through significant opportunities for the local supply chain and real prospects for further inward investment. By working flexibly and accelerating the decommissioning programme, the plan provides the opportunity for significant retraining to adapt to future challenges on the site and for other potential new nuclear

  9. Plan of Excellence: IHL System Strategic Plan. A Plan for the Mississippi Public University System.

    ERIC Educational Resources Information Center

    Mississippi State Board of Trustees of State Institutions of Higher Learning, Jackson.

    This guide presents a plan for excellence in education within Mississippi's public university system. It is based on system goals and priorities established by the Board of Trustees of State Institutions of Higher Learning (IHL), and is designed to facilitate planning, budgeting, and decision-making processes at the system and university levels.…

  10. Two Wrongs Do Not Make a Right: Flaws in Alternatives to Fee-for-Service Payment Plans Do Not Mean Fee-for-Service Is a Good Solution to Rising Prices

    PubMed Central

    Koppel, Ross

    2015-01-01

    Professor Naoki Ikegami’s "Fee-for-service payment – an evil practice that must be stamped out" summarizes many of the failings of alternatives to fee-for-service (FFS) payment systems. His article also offers several suggestions for improving FFS systems. However, even powerful arguments against many of the alternatives to FFS, does not make a convincing argument for FFS systems. In addition, there are significant misunderstandings in Professor Ikegami’s presentation of and use of United States payment methods, the role of private vs. public insurance systems, and the increasing role of "accountable care organizations. PMID:26340490

  11. Nuclear rDNA pseudogenes in Chagas disease vectors: evolutionary implications of a new 5.8S+ITS-2 paralogous sequence marker in triatomines of North, Central and northern South America.

    PubMed

    Bargues, M Dolores; Zuriaga, M Angeles; Mas-Coma, Santiago

    2014-01-01

    A pseudogene, paralogous to rDNA 5.8S and ITS-2, is described in Meccus dimidiata dimidiata, M. d. capitata, M. d. maculippenis, M. d. hegneri, M. sp. aff. dimidiata, M. p. phyllosoma, M. p. longipennis, M. p. pallidipennis, M. p. picturata, M. p. mazzottii, Triatoma mexicana, Triatoma nitida and Triatoma sanguisuga, covering North America, Central America and northern South America. Such a nuclear rDNA pseudogene is very rare. In the 5.8S gene, criteria for pseudogene identification included length variability, lower GC content, mutations regarding the functional uniform sequence, and relatively high base substitutions in evolutionary conserved sites. At ITS-2 level, criteria were the shorter sequence and large proportion of insertions and deletions (indels). Pseudogenic 5.8S and ITS-2 secondary structures were different from the functional foldings, different one another, showing less negative values for minimum free energy (mfe) and centroid predictions, and lower fit between mfe, partition function, and centroid structures. A complete characterization indicated a processed pseudogenic unit of the ghost type, escaping from rDNA concerted evolution and with functionality subject to constraints instead of evolving free by neutral drift. Despite a high indel number, low mutation number and an evolutionary rate similar to the functional ITS-2, that pseudogene distinguishes different taxa and furnishes coherent phylogenetic topologies with resolution similar to the functional ITS-2. The discovery of a pseudogene in many phylogenetically related species is unique in animals and allowed for an estimation of its palaeobiogeographical origin based on molecular clock data, inheritance pathways, evolutionary rate and pattern, and geographical spread. Additional to the technical risk to be considered henceforth, this relict pseudogene, designated as "ps(5.8S+ITS-2)", proves to be a valuable marker for specimen classification, phylogenetic analyses, and systematic

  12. Motivating Middle Schoolers Grades 5-8

    ERIC Educational Resources Information Center

    Jansen, Barbara

    2007-01-01

    What motivates middle school students? Hormones and success! There is not much that teachers can do about the hormones, but they sure can affect the success. "Teaching Information and Communication Technology Skills: The Big6 in Middle Schools," a new book from Linworth Publishing, offers classroom teachers and teacher librarians new strategies…

  13. 24 CFR 903.17 - What is the process for obtaining public comment on the plans?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... body must conduct a public hearing to discuss the PHA plan (either the 5-Year Plan and/or Annual Plan, as applicable) and invite public comment on the plan(s). The hearing must be conducted at a location... hearing is to take place, the PHA must: (1) Make the proposed PHA plan(s), the required attachments...

  14. 24 CFR 903.17 - What is the process for obtaining public comment on the plans?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... body must conduct a public hearing to discuss the PHA plan (either the 5-Year Plan and/or Annual Plan, as applicable) and invite public comment on the plan(s). The hearing must be conducted at a location... hearing is to take place, the PHA must: (1) Make the proposed PHA plan(s), the required attachments...

  15. 24 CFR 903.17 - What is the process for obtaining public comment on the plans?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... body must conduct a public hearing to discuss the PHA plan (either the 5-Year Plan and/or Annual Plan, as applicable) and invite public comment on the plan(s). The hearing must be conducted at a location... hearing is to take place, the PHA must: (1) Make the proposed PHA plan(s), the required attachments...

  16. 24 CFR 903.17 - What is the process for obtaining public comment on the plans?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... body must conduct a public hearing to discuss the PHA plan (either the 5-Year Plan and/or Annual Plan, as applicable) and invite public comment on the plan(s). The hearing must be conducted at a location... hearing is to take place, the PHA must: (1) Make the proposed PHA plan(s), the required attachments...

  17. Is Strategic Planning for Technology an Oxymoron?

    ERIC Educational Resources Information Center

    Ringle, Martin; Updegrove, Daniel

    1998-01-01

    The key to making optimal use of time, energy, and institutional resources in college and university technology planning is to understand important differences between long-term socioeconomic planning and short-term operational planning. A ten-step procedure that focuses on process rather than product, and allows ready reallocation of resources as…

  18. Strategic Human Resource Planning in Academia

    ERIC Educational Resources Information Center

    Ulferts, Gregory; Wirtz, Patrick; Peterson, Evan

    2009-01-01

    A strategic plan guides a college in successfully meeting its mission. Based on the strategic plan, a college can develop a human resource plan that will allow it to make management decisions in the present to support the future direction of the college. The overall purpose of human resource management is to: (1) ensure the organization has…

  19. 40 CFR 7.75 - Transition plan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Transition plan. 7.75 Section 7.75... of Handicap § 7.75 Transition plan. If structural changes to facilities are necessary to make the program or activity accessible to handicapped persons, a recipient must prepare a transition plan....

  20. Foundations and Applications of Generalized Planning

    ERIC Educational Resources Information Center

    Srivastava, Siddharth

    2010-01-01

    Research in the field of Automated Planning is largely focused on the problem of constructing plans or sequences of actions for going from a specific initial state to a goal state. The complexity of this task makes it desirable to find "generalized" plans which can solve multiple problem instances from a class of similar problems. Most approaches…

  1. Solid Waste Management Planning--A Methodology

    ERIC Educational Resources Information Center

    Theisen, Hilary M.; And Others

    1975-01-01

    This article presents a twofold solid waste management plan consisting of a basic design methodology and a decision-making methodology. The former provides a framework for the developing plan while the latter builds flexibility into the design so that there is a model for use during the planning process. (MA)

  2. 40 CFR 7.75 - Transition plan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Transition plan. 7.75 Section 7.75... of Handicap § 7.75 Transition plan. If structural changes to facilities are necessary to make the program or activity accessible to handicapped persons, a recipient must prepare a transition plan....

  3. 40 CFR 7.75 - Transition plan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Transition plan. 7.75 Section 7.75... of Handicap § 7.75 Transition plan. If structural changes to facilities are necessary to make the program or activity accessible to handicapped persons, a recipient must prepare a transition plan....

  4. 24 CFR 3282.302 - State plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... to carrying out its State plan, (13) Indicate that State Law requires manufacturers, distributors... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false State plan. 3282.302 Section 3282... State plan. A State wishing to qualify and act as a SAA under this subpart shall make a State...

  5. 24 CFR 3282.302 - State plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the State shall devote adequate funds to carrying out its State plan, (13) Indicate that State Law... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false State plan. 3282.302 Section 3282... State plan. A State wishing to qualify and act as an SAA under this subpart shall make a State...

  6. 24 CFR 3282.302 - State plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... to carrying out its State plan, (13) Indicate that State Law requires manufacturers, distributors... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false State plan. 3282.302 Section 3282... State plan. A State wishing to qualify and act as a SAA under this subpart shall make a State...

  7. 24 CFR 3282.302 - State plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... to carrying out its State plan, (13) Indicate that State Law requires manufacturers, distributors... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false State plan. 3282.302 Section 3282... State plan. A State wishing to qualify and act as a SAA under this subpart shall make a State...

  8. 1994 Site Development Plan: A plan with vision

    SciTech Connect

    Not Available

    1994-07-01

    The 1994 Lawrence Livermore National Laboratory Site Development Plan has been developed during a period of great change and uncertainty. Our goal is to make possible the best use of the Laboratory`s resources to meet shifting national priorities in the post-Cold War world. Site Planning is an important component of the overall Laboratory strategic planning process. This plan focuses on opportunities for the Laboratory as well as on key site development issues including facility construction, redevelopment and reuse, site accessibility, and security. A major challenge is to achieve sufficient stability in the site planning and execution so that the processes of construction can occur efficiently while at the same time providing sufficient flexibility in site facilities so that a range of changing national needs can be accommodated. We are closely coupled to the DOE strategic planning process to meet this challenge.

  9. Test plan :

    SciTech Connect

    Dwyer, Stephen F.

    2013-05-01

    This test plan is a document that provides a systematic approach to the planned testing of rooftop structures to determine their actual load carrying capacity. This document identifies typical tests to be performed, the responsible parties for testing, the general feature of the tests, the testing approach, test deliverables, testing schedule, monitoring requirements, and environmental and safety compliance.

  10. Expedition Planning.

    ERIC Educational Resources Information Center

    Ewert, Alan

    Planning an expedition, particularly an expedition to climb Mount McKinley, can appear monumental. Not only must the obvious items like food, equipment and personnel be carefully planned, but attention must also focus on "insignificant" items like applications and reservations which, if forgotten, could mean the difference between a successful or…

  11. Inspired Planning

    ERIC Educational Resources Information Center

    Erickson, Paul W.

    2009-01-01

    Long-range facility planning is a comprehensive process for preparing education institutions for the future and confirm that facilities meet current needs. A long-range facilities plan (LRFP) evaluates how facilities support programs and the educational needs of students, staff and the community. Each school district or college has unique needs…

  12. Transition Planning

    ERIC Educational Resources Information Center

    Statfeld, Jenna L.

    2011-01-01

    Post-school transition is the movement of a child with disabilities from school to activities that occur after the completion of school. This paper provides information about: (1) post-school transition; (2) transition plan; (3) transition services; (4) transition planning; (5) vocational rehabilitation services; (6) services that are available…

  13. Planning Monographs.

    ERIC Educational Resources Information Center

    Delaware State Dept. of Public Instruction, Dover. Div. of Research, Planning, and Evaluation.

    These seven monographs survey the issues and problems of (1) sensitivity training, (2) differentiated staffing, (3) planning-programing-budgeting systems, (4) systems analysis, (5) the delphi technique, (6) performance contracting, and (7) educational vouchers. The papers are designed to be used as a matrix for reference and planning by interested…

  14. [Henan planned parenthood meeting].

    PubMed

    1980-05-16

    A Henan provincial planned parenthood report meeting was recently held in Xinyang. The meeting called on the province to make vigorous remedial measures before the wheat harvest to deal with pregnancies not covered by the plan and resolutely reduce the population growth rate. Reports were delivered by representatives of 10 prefectures and 3 counties. The participants pointed out: To shift the focus of planned parenthood work to promoting the idea that a couple should have only 1 child and to reduce the province's natural population growth rate to below 10/1000 this year and to below 5/1000 by 1985 constitute a glorious and arduous battle task for the whole party and the people of the whole province. Provinical CCP committee Secretary Zhang Shude spoke at the conclusion of the meeting.

  15. Volumetric Properties of the Mixture Dimethyl carbonate C3H6O3 + C10H22O5 2,5,8,11,14-Pentaoxapentadecane (VMSD1211, LB4862_V)

    NASA Astrophysics Data System (ADS)

    Cibulka, I.; Fontaine, J.-C.; Sosnkowska-Kehiaian, K.; Kehiaian, H. V.

    This document is part of Subvolume C 'Binary Liquid Systems of Nonelectrolytes III' of Volume 26 'Heats of Mixing, Vapor-Liquid Equilibrium, and Volumetric Properties of Mixtures and Solutions' of Landolt-Börnstein Group IV 'Physical Chemistry'. It contains the Chapter 'Volumetric Properties of the Mixture Dimethyl carbonate C3H6O3 + C10H22O5 2,5,8,11,14-Pentaoxapentadecane (VMSD1211, LB4862_V)' providing data from direct low-pressure dilatometric measurement of molar excess volume at variable mole fraction and constant temperature.

  16. Volumetric Properties of the Mixture Dimethyl carbonate C3H6O3 + C10H22O5 2,5,8,11,14-Pentaoxapentadecane (VMSD1112, LB4865_V)

    NASA Astrophysics Data System (ADS)

    Cibulka, I.; Fontaine, J.-C.; Sosnkowska-Kehiaian, K.; Kehiaian, H. V.

    This document is part of Subvolume C 'Binary Liquid Systems of Nonelectrolytes III' of Volume 26 'Heats of Mixing, Vapor-Liquid Equilibrium, and Volumetric Properties of Mixtures and Solutions' of Landolt-Börnstein Group IV 'Physical Chemistry'. It contains the Chapter 'Volumetric Properties of the Mixture Dimethyl carbonate C3H6O3 + C10H22O5 2,5,8,11,14-Pentaoxapentadecane (VMSD1112, LB4865_V)' providing data by calculation of mass density in the single-phase region(s) from low-pressure dilatometric measurements of the molar excess volume at variable mole fraction and constant temperature.

  17. Categorization = Decision Making + Generalization

    PubMed Central

    Seger, Carol A; Peterson, Erik J.

    2013-01-01

    We rarely, if ever, repeatedly encounter exactly the same situation. This makes generalization crucial for real world decision making. We argue that categorization, the study of generalizable representations, is a type of decision making, and that categorization learning research would benefit from approaches developed to study the neuroscience of decision making. Similarly, methods developed to examine generalization and learning within the field of categorization may enhance decision making research. We first discuss perceptual information processing and integration, with an emphasis on accumulator models. We then examine learning the value of different decision making choices via experience, emphasizing reinforcement learning modeling approaches. Next we discuss how value is combined with other factors in decision making, emphasizing the effects of uncertainty. Finally, we describe how a final decision is selected via thresholding processes implemented by the basal ganglia and related regions. We also consider how memory related functions in the hippocampus may be integrated with decision making mechanisms and contribute to categorization. PMID:23548891

  18. What Makes the Fizz?

    ERIC Educational Resources Information Center

    Shimkanin, John

    1995-01-01

    Presents an activity to answer the question, "What makes soda pop fizz?". Lists necessary materials and describes the procedure for making soda pop. Discusses the fermentation process and how it occurs. (NB)

  19. The ABCs of physician billing compliance plans.

    PubMed

    Apple, G J; Bowman, B

    1996-07-01

    As it evolves, an organization's compliance plan will become an effective risk-management tool. As the price for noncompliance becomes ever higher, the development and implementation of a corporate compliance plan makes both common and fiscal sense. A compliance plan should not be a program that is rolled out and then allowed to sit on the shelf and gather dust. The only thing worse than not having a compliance plan is having one and not following it.

  20. Southwest elevation, roof plan, site plan & main floor plan, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Southwest elevation, roof plan, site plan & main floor plan, loft plan, section looking east, north window head detail - Richard Buckminster Fuller & Anne Hewlett Fuller Dome Home, 407 South Forest Avenue, Carbondale, Jackson County, IL

  1. Third Floor Plan, Second Floor Plan, First Floor Plan, Ground ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Third Floor Plan, Second Floor Plan, First Floor Plan, Ground Floor Plan, West Bunkhouse - Kennecott Copper Corporation, On Copper River & Northwestern Railroad, Kennicott, Valdez-Cordova Census Area, AK

  2. An experiment with interactive planning models

    NASA Technical Reports Server (NTRS)

    Beville, J.; Wagner, J. H.; Zannetos, Z. S.

    1970-01-01

    Experiments on decision making in planning problems are described. Executives were tested in dealing with capital investments and competitive pricing decisions under conditions of uncertainty. A software package, the interactive risk analysis model system, was developed, and two controlled experiments were conducted. It is concluded that planning models can aid management, and predicted uses of the models are as a central tool, as an educational tool, to improve consistency in decision making, to improve communications, and as a tool for consensus decision making.

  3. I: Making Art

    ERIC Educational Resources Information Center

    Rosenfeld, Malke; Johnson, Marquetta; Plemons, Anna; Makol, Suzanne; Zanskas, Meghan; Dzula, Mark; Mahoney, Meg Robson

    2014-01-01

    Writing about the teaching artist practice should mean writing about art making. As both teacher and artist, the authors are required to be cognizant of their own art-making processes, both how it works and why it is important to them, in order to make this process visible to their students. They also need the same skills to write about how and…

  4. Information in Educational Decision Making in Greece.

    ERIC Educational Resources Information Center

    Kassimati, Koula

    This Unesco report, one in a series, examines the sources of data used in educational decision making in Greece and proposes innovations in the information system to promote educational planning. The main source of quantitative data is the National Statistical Service of Greece which regularly publishes data concerned with all educational levels.…

  5. Personal Decision Making. Focus on Economics.

    ERIC Educational Resources Information Center

    Leet, Don R.; Charkins, R. J.; Lang, Nancy A.; Lopus, Jane S.; Tamaribuchi, Gail

    This book highlights and examines basic economic concepts as they relate to consumer, business, social, and personal choices. Students are shown connections between their classroom learning and their real-world experiences in budgeting, career planning, credit management, and housing. The set of 15 lessons include: (1) "Decision Making: Scarcity,…

  6. Making an English Language Teaching Videotape.

    ERIC Educational Resources Information Center

    Brennan, Moya; Miller, Janet Woodbury

    1982-01-01

    Discusses step-by-step approach for teachers to make their own videotapes including planning the format of the program, organizing the students, how to teach with it, exercises to accompany it, and follow-up activities. Illustrates procedure with examples from language teaching videotape made with university students in China. (Author/BK)

  7. RAPD analysis and sequencing of ITS1/5.8S rRNA/ITS2 and Fe-hydrogenase as tools for genetic classification of potentially pathogenic isolates of Trichomonas gallinae.

    PubMed

    Sansano-Maestre, José; Martínez-Herrero, María Del Carmen; Garijo-Toledo, María Magdalena; Gómez-Muñoz, María Teresa

    2016-08-01

    Trichomonas gallinae is a worldwide parasite that causes oropharyngeal avian trichomonosis. During eight years, 60 axenic isolates were obtained from different bird species and characterized by three molecular methods: RAPD analysis and PCR-sequencing of ITS1/5.8S rRNA/ITS2 fragment and Fe-hydrogenase gene. We have found two genotypes of ITS1/5.8S rRNA/ITS2 widely distributed among bird populations, a new variant and also two sequences with mixed pattern. Genotype ITS-OBT-Tg-1 was associated with the presence of gross lesions in birds. We have found eight genotypes of the Fe-hydrogenase (A1, A2, C2, C2.1, C4, C5, C6 and C7), three of them are new reports (C5, C6 and C7), and also three sequences with mixed pattern. Subtype A1 of the Fe-hydrogenase was also related with the presence of lesions. RAPD analyses included most of the strains isolated from animals with lesions in one of the sub-clusters. Potentially pathogenic isolates of T. gallinae obtained in this study fulfill the following criteria with one exception: isolated from lesions+ITS-OBT-Tg-1 genotype+FeHyd A1+RAPD sub-cluster I2.

  8. Utility of ITS1-5.8S-ITS2 and 16S mitochondrial DNA sequences for species identification and phylogenetic inference within the Rhinonyssus coniventris species complex (Acari: Rhinonyssidae).

    PubMed

    de Rojas, Manuel; Ubeda, José Manuel; Cutillas, Cristina; Mora, Maria Dolores; Ariza, Concepción; Guevara, Diego

    2007-04-01

    The complete internal transcribed spacer 1 (ITS1), 5.8S rDNA, and ITS2 region of the ribosomal DNA and a 390-bp region of the 16S rDNA gene from five taxa belonging to Rhinonyssus (Rhinonyssus vanellus, Rhinonyssus tringae, Rhinonyssus neglectus, Rhinonyssus echinipes from Kentish plover, and Rhinonyssus echinipes from grey plover) were sequenced to examine the level of sequence variation and the taxonomic levels to show utility in phylogeny estimation. Our data show that these molecular markers can help to discriminate between species and populations included in the Rhinonyssus coniventris complex (R. tringae, R. neglectus, R. echinipes), which are morphologically very close and difficult to separate by classic methods. A comparative study with sequences from other rhinonyssid mites previously published was also carried out. The resulting phylogenetic tree inferred from ITS1-5.8S-ITS2 region sequences obtained in this paper, together with those from other 11 taxa of rhinonyssid, shows slight differences from the current taxonomy of the Rhinonyssidae. This study appeals for the revision of the taxonomic status of the R. coniventris complex, as well as for the species included within it.

  9. A new insight into high-strength Ti62Nb12.2Fe13.6Co6.4Al5.8 alloys with bimodal microstructure fabricated by semi-solid sintering.

    PubMed

    Liu, L H; Yang, C; Kang, L M; Qu, S G; Li, X Q; Zhang, W W; Chen, W P; Li, Y Y; Li, P J; Zhang, L C

    2016-03-31

    It is well known that semi-solid forming could only obtain coarse-grained microstructure in a few alloy systems with a low melting point, such as aluminum and magnesium alloys. This work presents that semi-solid forming could also produce novel bimodal microstructure composed of nanostructured matrix and micro-sized (CoFe)Ti2 twins in a titanium alloy, Ti62Nb12.2Fe13.6Co6.4Al5.8. The semi-solid sintering induced by eutectic transformation to form a bimodal microstructure in Ti62Nb12.2Fe13.6Co6.4Al5.8 alloy is a fundamentally different approach from other known methods. The fabricated alloy exhibits high yield strength of 1790 MPa and plastic strain of 15.5%. The novel idea provides a new insight into obtaining nano-grain or bimodal microstructure in alloy systems with high melting point by semi-solid forming and into fabricating high-performance metallic alloys in structural applications.

  10. Characterization of the rDNA unit and sequence analysis of the small subunit rRNA and 5.8S rRNA genes from Tritrichomonas foetus.

    PubMed

    Chakrabarti, D; Dame, J B; Gutell, R R; Yowell, C A

    1992-05-01

    The ribosomal RNA gene unit of the protozoan parasite Tritrichomonas foetus has been cloned and analyzed. Southern blot analysis of the genomic DNA showed that the ribosomal RNA gene unit is organized as a tandem head to tail repeat with a unit length of 6 kb. By Northern analysis a primary transcript of 5.8 kb was detected. Copy number analysis showed the presence of 12 copies of the ribosomal RNA gene unit. The lengths of the small subunit ribosomal RNA and 5.8S ribosomal RNA are 1571 bp and 159 bp, respectively, as determined by sequence analysis. The T. foetus small subunit ribosomal RNA sequence is one of the shortest eukaryotic small subunit rRNA sequences, similar in length to those from 2 other amitochondrial protists. Although shorter than the majority of the eukaryotic small subunit ribosomal RNAs, this sequence maintains the primary and secondary structure common to all eukaryotic small subunit ribosomal RNA structures, while truncating sequences found within the eukaryotic variable regions. The length of the large subunit ribosomal RNA was measured at 2.5 kb.

  11. A new insight into high-strength Ti62Nb12.2Fe13.6Co6.4Al5.8 alloys with bimodal microstructure fabricated by semi-solid sintering

    NASA Astrophysics Data System (ADS)

    Liu, L. H.; Yang, C.; Kang, L. M.; Qu, S. G.; Li, X. Q.; Zhang, W. W.; Chen, W. P.; Li, Y. Y.; Li, P. J.; Zhang, L. C.

    2016-03-01

    It is well known that semi-solid forming could only obtain coarse-grained microstructure in a few alloy systems with a low melting point, such as aluminum and magnesium alloys. This work presents that semi-solid forming could also produce novel bimodal microstructure composed of nanostructured matrix and micro-sized (CoFe)Ti2 twins in a titanium alloy, Ti62Nb12.2Fe13.6Co6.4Al5.8. The semi-solid sintering induced by eutectic transformation to form a bimodal microstructure in Ti62Nb12.2Fe13.6Co6.4Al5.8 alloy is a fundamentally different approach from other known methods. The fabricated alloy exhibits high yield strength of 1790 MPa and plastic strain of 15.5%. The novel idea provides a new insight into obtaining nano-grain or bimodal microstructure in alloy systems with high melting point by semi-solid forming and into fabricating high-performance metallic alloys in structural applications.

  12. A new insight into high-strength Ti62Nb12.2Fe13.6Co6.4Al5.8 alloys with bimodal microstructure fabricated by semi-solid sintering

    PubMed Central

    Liu, L. H.; Yang, C.; Kang, L. M.; Qu, S. G.; Li, X. Q.; Zhang, W. W.; Chen, W. P.; Li, Y. Y.; Li, P. J.; Zhang, L. C.

    2016-01-01

    It is well known that semi-solid forming could only obtain coarse-grained microstructure in a few alloy systems with a low melting point, such as aluminum and magnesium alloys. This work presents that semi-solid forming could also produce novel bimodal microstructure composed of nanostructured matrix and micro-sized (CoFe)Ti2 twins in a titanium alloy, Ti62Nb12.2Fe13.6Co6.4Al5.8. The semi-solid sintering induced by eutectic transformation to form a bimodal microstructure in Ti62Nb12.2Fe13.6Co6.4Al5.8 alloy is a fundamentally different approach from other known methods. The fabricated alloy exhibits high yield strength of 1790 MPa and plastic strain of 15.5%. The novel idea provides a new insight into obtaining nano-grain or bimodal microstructure in alloy systems with high melting point by semi-solid forming and into fabricating high-performance metallic alloys in structural applications. PMID:27029858

  13. RAPD analysis and sequencing of ITS1/5.8S rRNA/ITS2 and Fe-hydrogenase as tools for genetic classification of potentially pathogenic isolates of Trichomonas gallinae.

    PubMed

    Sansano-Maestre, José; Martínez-Herrero, María Del Carmen; Garijo-Toledo, María Magdalena; Gómez-Muñoz, María Teresa

    2016-08-01

    Trichomonas gallinae is a worldwide parasite that causes oropharyngeal avian trichomonosis. During eight years, 60 axenic isolates were obtained from different bird species and characterized by three molecular methods: RAPD analysis and PCR-sequencing of ITS1/5.8S rRNA/ITS2 fragment and Fe-hydrogenase gene. We have found two genotypes of ITS1/5.8S rRNA/ITS2 widely distributed among bird populations, a new variant and also two sequences with mixed pattern. Genotype ITS-OBT-Tg-1 was associated with the presence of gross lesions in birds. We have found eight genotypes of the Fe-hydrogenase (A1, A2, C2, C2.1, C4, C5, C6 and C7), three of them are new reports (C5, C6 and C7), and also three sequences with mixed pattern. Subtype A1 of the Fe-hydrogenase was also related with the presence of lesions. RAPD analyses included most of the strains isolated from animals with lesions in one of the sub-clusters. Potentially pathogenic isolates of T. gallinae obtained in this study fulfill the following criteria with one exception: isolated from lesions+ITS-OBT-Tg-1 genotype+FeHyd A1+RAPD sub-cluster I2. PMID:27473993

  14. Making strategy: learning by doing.

    PubMed

    Christensen, C M

    1997-01-01

    Companies find it difficult to change strategy for many reasons, but one stands out: strategic thinking is not a core managerial competence at most companies. Executives hone their capabilities by tackling problems over and over again. Changing strategy, however, is not usually a task that they face repeatedly. Once companies have found a strategy that works, they want to use it, not change it. Consequently, most managers do not develop a competence in strategic thinking. This Manager's Tool Kit presents a three-stage method executives can use to conceive and implement a creative and coherent strategy themselves. The first stage is to identify and map the driving forces that the company needs to address. The process of mapping provides strategy-making teams with visual representations of team members' assumptions, those pictures, in turn, enable managers to achieve consensus in determining the driving forces. Once a senior management team has formulated a new strategy, it must align the strategy with the company's resource-allocation process to make implementation possible. Senior management teams can translate their strategy into action by using aggregate project planning. And management teams that link strategy and innovation through that planning process will develop a competence in implementing strategic change. The author guides the reader through the three stages of strategy making by examining the case of a manufacturing company that was losing ground to competitors. After mapping the driving forces, the company's senior managers were able to devise a new strategy that allowed the business to maintain a competitive advantage in its industry.

  15. Making detailed predictions makes (some) predictions worse

    NASA Astrophysics Data System (ADS)

    Kelly, Theresa F.

    In this paper, we investigate whether making detailed predictions about an event makes other predictions worse. Across 19 experiments, 10,895 participants, and 415,960 predictions about 724 professional sports games, we find that people who made detailed predictions about sporting events (e.g., how many hits each baseball team would get) made worse predictions about more general outcomes (e.g., which team would win). We rule out that this effect is caused by inattention or fatigue, thinking too hard, or a differential reliance on holistic information about the teams. Instead, we find that thinking about game-relevant details before predicting winning teams causes people to give less weight to predictive information, presumably because predicting details makes information that is relatively useless for predicting the winning team more readily accessible in memory and therefore incorporated into forecasts. Furthermore, we show that this differential use of information can be used to predict what kinds of games will and will not be susceptible to the negative effect of making detailed predictions.

  16. Hospice Decision Making: Diagnosis Makes a Difference

    ERIC Educational Resources Information Center

    Waldrop, Deborah P.; Meeker, Mary Ann

    2012-01-01

    Purpose: This study explored the process of decision making about hospice enrollment and identified factors that influence the timing of that decision. Methods: This study employed an exploratory, descriptive, cross-sectional design and was conducted using qualitative methods. In-depth in-person semistructured interviews were conducted with 36…

  17. Art Makes Sense: Making Sense through Art

    ERIC Educational Resources Information Center

    Billington, Lisa; Pavone, Mindy

    2010-01-01

    The news is sometimes frightening, but reacting to a disaster in a positive way empowers students to make a difference. On January 12, 2010, a catastrophic earthquake occurred in Haiti. An estimated three million people were affected and an estimated 230,000 people died. In response to this tragic event, the author's eighth-grade class viewed and…

  18. Environmental Implementation Plan

    SciTech Connect

    Not Available

    1994-02-01

    The Environmental Implementation Plan (EIP) is a dynamic long-range environmental-protection plan for SRS. The EIP communicates the current and future (five year) environmental plans from individual organizations and divisions as well as site environmental initiatives which are designed to protect the environment and meet or exceed compliance with changing environmental/ regulatory requirements. Communication with all site organizations is essential for making the site environmental planning process work. Demonstrating environmental excellence is a high priority embodied in DOE and WSRC policy. Because of your support and participation in the three EIP initiatives; Reflections, Sectional Revision, and Integrated Planning, improvements are being made to the EIP and SRS environmental protection programs. I appreciate the ``Partnership in Environmental Excellence`` formed by the environmental coordinators and professionals who work daily toward our goal of compliance and environmental excellence. I look forward to seeing continued success and improvement in our environmental protection programs through combined efforts of all site organizations to protect our employees, the public health, and the environment. Together, we will achieve our site vision for SRS to be the recognized model for Environmental Excellence in the DOE Nuclear Weapons Complex.

  19. 76 FR 77300 - Alaska Federal Lands Long Range Transportation Plan

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... transportation planning and decision-making processes. Such cooperation is accomplished through developing common... LRTP--This draft plan describes the benefits of and actions for coordinated planning and decision making among federal land management agencies (FLMA) involved in this Alaska Federal Lands Long...

  20. Planning to avoid risk or planning for a positive life: the relationship between release plan valence and reoffending.

    PubMed

    Dickson, Sophie R; Polaschek, Devon L L

    2014-12-01

    Following release from prison, offenders face a variety of challenges reintegrating back into the community. As a result, many high-risk offenders fail quickly. Research has shown that good quality release plans-plans to address offenders' basic needs in the community-are related to reduced rates of recidivism during this risky time. But what makes a good plan? The current study examines release plan valence: whether plans are approach-oriented or avoidance-oriented. Although it was hypothesized that approach plans would be related to better outcomes, the results showed no relationship between release plan valence and reoffending rates. These results indicate that planning for a positive life and plans for risk management are equally important in reducing risk in the community.

  1. Planning to avoid risk or planning for a positive life: the relationship between release plan valence and reoffending.

    PubMed

    Dickson, Sophie R; Polaschek, Devon L L

    2014-12-01

    Following release from prison, offenders face a variety of challenges reintegrating back into the community. As a result, many high-risk offenders fail quickly. Research has shown that good quality release plans-plans to address offenders' basic needs in the community-are related to reduced rates of recidivism during this risky time. But what makes a good plan? The current study examines release plan valence: whether plans are approach-oriented or avoidance-oriented. Although it was hypothesized that approach plans would be related to better outcomes, the results showed no relationship between release plan valence and reoffending rates. These results indicate that planning for a positive life and plans for risk management are equally important in reducing risk in the community. PMID:24013767

  2. 42 CFR 423.590 - Timeframes and responsibility for making redeterminations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) If the Part D plan sponsor makes a redetermination that is completely favorable to the enrollee, the Part D plan sponsor must notify the enrollee in writing of its redetermination (and effectuate it in... Part D plan sponsor makes a redetermination that affirms, in whole or in part, its adverse...

  3. Make a Nature Trail

    ERIC Educational Resources Information Center

    Johnson, Janice K.

    1973-01-01

    Discusses the planning, construction, use, and maintenance of a nature trail. Ideal for demonstrating interrelationships between plants and animals, conservation practices, wildlife management, plant succession, forestry, geologic features and other scientific phenomena. (JR)

  4. Trimodal interpretation of constraints for planning

    NASA Technical Reports Server (NTRS)

    Krieger, David; Brown, Richard

    1987-01-01

    Constraints are used in the CAMPS knowledge based planning system to represent those propositions that must be true for a plan to be acceptable. CAMPS introduces the make-mode for interpreting a constraint. Given an unsatisfied constraint, make evaluation mode suggests planning actions which, if taken, would result in a modified plan in which the constraint in question may be satisfied. These suggested planning actions, termed delta-tuples, are the raw material of intelligent plan repair. They are used both in debugging an almost-right plan and in replanning due to changing situations. Given a defective plan in which some set of constraints are violated, a problem solving strategy selects one or more constraints as a focus of attention. These selected constraints are evaluated in the make-mode to produce delta-tuples. The problem solving strategy then reviews the delta-tuples according to its application and problem-specific criteria to find the most acceptable change in terms of success likelihood and plan disruption. Finally, the problem solving strategy makes the suggested alteration to the plan and then rechecks constraints to find any unexpected consequences.

  5. The NASA planning process, appendix D. [as useful planning approach for solving urban problems

    NASA Technical Reports Server (NTRS)

    Annett, H. A.

    1973-01-01

    The planning process is outlined which NASA used in making some fundamental post-Apollo decisions concerning the reuseable space shuttle and the orbiting laboratory. It is suggested that the basic elements and principles of the process, when combined, form a useful planning approach for solving urban problems. These elements and principles are defined along with the basic strengths of the planning model.

  6. Introduction to Strategic Planning in Student Affairs: A Model for Process and Elements of a Plan

    ERIC Educational Resources Information Center

    Ellis, Shannon E.

    2010-01-01

    Planning from a strategic perspective has been a mainstay of organizational management for decades. Founded in the private sector, strategic planning is now embraced by the nonprofit world as a catalyst for sound resource allocation, transformative decision making, and motivating staff. Student affairs professionals who think, plan, and act…

  7. 29 CFR 4042.4 - Disclosure of information by plan administrator or plan sponsor.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... or plan sponsor has submitted to PBGC in connection with the plan termination. (2) Requirements. A... connection with the plan termination; (iii) State the name of the person making the request for information... the definition of affected party under § 4001.2 of this chapter; and (iv) Be signed by the...

  8. Making health insurers insure.

    PubMed

    Ortolon, Ken

    2010-12-01

    A section of the Patient Protection and Affordable Care Act requires health plans to maintain a minimum "medical loss ratio," or MLR, of between 80 percent and 85 percent. If they don't, they could be ordered to refund some premium dollars to their beneficiaries. Texas Medical Association officials say the new MLR provision could force health plans to spend more time providing insurance and less time meddling in patient care. But that is still unclear. PMID:21174243

  9. Training for Aviation Decision Making: The Naturalistic Decision Making Perspective

    NASA Technical Reports Server (NTRS)

    Orasanu, Judith; Shafto, Michael G. (Technical Monitor)

    1995-01-01

    This paper describes the implications of a naturalistic decision making (NDM) perspective for training air crews to make flight-related decisions. The implications are based on two types of analyses: (a) identification of distinctive features that serve as a basis for classifying a diverse set of decision events actually encountered by flight crews, and (b) performance strategies that distinguished more from less effective crews flying full-mission simulators, as well as performance analyses from NTSB accident investigations. Six training recommendations are offered: (1) Because of the diversity of decision situations, crews need to be aware that different strategies may be appropriate for different problems; (2) Given that situation assessment is essential to making a good decision, it is important to train specific content knowledge needed to recognize critical conditions, to assess risks and available time, and to develop strategies to verify or diagnose the problem; (3) Tendencies to oversimplify problems may be overcome by training to evaluate options in terms of goals, constraints, consequences, and prevailing conditions; (4) In order to provide the time to gather information and consider options, it is essential to manage the situation, which includes managing crew workload, prioritizing tasks, contingency planning, buying time (e.g., requesting holding or vectors), and using low workload periods to prepare for high workload; (5) Evaluating resource requirements ("What do I need?") and capabilities ("'What do I have?" ) are essential to making good decisions. Using resources to meet requirements may involve the cabin crew, ATC, dispatchers, and maintenance personnel; (6) Given that decisions must often be made under high risk, time pressure, and workload, train under realistic flight conditions to promote the development of robust decision skills.

  10. Making tough choices: HIV ethical decision making.

    PubMed

    1999-05-01

    A panel of the American Psychological Association (APA) has developed a simple, user friendly process to facilitate ethical and clinical decision making in cases involving HIV disease. The model is based on the five ethical principles of autonomy, beneficence, nonmaleficence, fidelity, and justice. This article examines how the model could be applied to a hypothetical case of a private practice client and his therapist. The ethical question in this case concerns whether to reveal a patient's serostatus to his wife.

  11. Plan Execution Interchange Language (PLEXIL)

    NASA Technical Reports Server (NTRS)

    Estlin, Tara; Jonsson, Ari; Pasareanu, Corina; Simmons, Reid; Tso, Kam; Verma, Vandi

    2006-01-01

    Plan execution is a cornerstone of spacecraft operations, irrespective of whether the plans to be executed are generated on board the spacecraft or on the ground. Plan execution frameworks vary greatly, due to both different capabilities of the execution systems, and relations to associated decision-making frameworks. The latter dependency has made the reuse of execution and planning frameworks more difficult, and has all but precluded information sharing between different execution and decision-making systems. As a step in the direction of addressing some of these issues, a general plan execution language, called the Plan Execution Interchange Language (PLEXIL), is being developed. PLEXIL is capable of expressing concepts used by many high-level automated planners and hence provides an interface to multiple planners. PLEXIL includes a domain description that specifies command types, expansions, constraints, etc., as well as feedback to the higher-level decision-making capabilities. This document describes the grammar and semantics of PLEXIL. It includes a graphical depiction of this grammar and illustrative rover scenarios. It also outlines ongoing work on implementing a universal execution system, based on PLEXIL, using state-of-the-art rover functional interfaces and planners as test cases.

  12. The Turkish Educational Planning Experience in a Comparative Perspective

    ERIC Educational Resources Information Center

    Aypay, Ahmet; Isik, Halil

    2006-01-01

    The purpose of this article is to reexamine the 40 years of educational planning experience in Turkey comparatively with the educational planning experience in the international arena. Turkey has used educational planning since 1963. Planning in general has been defined as a decision-making process to reach certain goals in the future. This study…

  13. 76 FR 7098 - Dealer Floor Plan Pilot Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ... ADMINISTRATION 13 CFR Parts 120 and 121 Dealer Floor Plan Pilot Program AGENCY: U.S. Small Business... Dealer Floor Plan Pilot Program to make available 7(a) loan guaranties for lines of credit that provide floor plan financing. This new Dealer Floor Plan Pilot Program was created in the Small Business...

  14. Lake Washington's Master Plan--A System for Growth.

    ERIC Educational Resources Information Center

    Scarr, L. E.

    1988-01-01

    Describes Lake Washington (Washington) School District's master plan to balance building-based decision-making and administrative input, encourage collegiality, and respond positively to change. For each building, the district master plan is mirrored by a locally developed master plan. Each teacher is also developing a classroom plan. (MLH)

  15. Planning applications in image analysis

    NASA Technical Reports Server (NTRS)

    Boddy, Mark; White, Jim; Goldman, Robert; Short, Nick, Jr.

    1994-01-01

    We describe two interim results from an ongoing effort to automate the acquisition, analysis, archiving, and distribution of satellite earth science data. Both results are applications of Artificial Intelligence planning research to the automatic generation of processing steps for image analysis tasks. First, we have constructed a linear conditional planner (CPed), used to generate conditional processing plans. Second, we have extended an existing hierarchical planning system to make use of durations, resources, and deadlines, thus supporting the automatic generation of processing steps in time and resource-constrained environments.

  16. The epithelial differentiating activity in vivo of (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl) -1-propenyl]benzoic acid and 4,4-difluororetinoic acid.

    PubMed Central

    Miller, D A; Stephens-Jarnagin, A; DeLuca, H F

    1985-01-01

    Female rats fed on a vitamin A-deficient diet from weaning were oophorectomized after introitus and used to test analogues of all-trans-retinoic acid for epithelial differentiation activity by the vaginal-smear assay. Several modifications have been made in the assay; housing facilities were modified, the diet changed and the existing scoring system for the assay altered. The arotinoid (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylenyl)-1 -propenyl] benzoic acid was 12-fold more active than all-trans-retinoic acid, which had a 50% effective dose (ED50) of 80 pmol/vagina. The fluorinated analogue 4,4-difluororetinoic acid had an ED50 of 2.5 nmol/vagina and was therefore 30-fold less active than all-trans-retinoic acid. PMID:3994687

  17. Mid-infrared (5-12-microm) and limited (5.5-8.5-microm) single-knob tuning generated by difference-frequency mixing in single-crystal AgGaS2.

    PubMed

    Haidar, S; Nakamura, K; Niwa, E; Masumoto, K; Ito, H

    1999-03-20

    We describe tunable 5-12-microm mid-infrared generation in single-crystal silver gallium sulfide (AgGaS(2)), from nonlinear optical difference-frequency generation. Signal and idler waves obtained from a Nd:YAG laser-pumped LiNbO(3) optical parametric oscillator (OPO) were mixed in AgGaS(2) crystal to yield difference-frequency waves. For the efficient generation of difference frequency, an unstable resonator was employed as the OPO to reduce output beam divergence. A maximum difference-frequency power of 95 microJ/pulse was obtained near 7.5 microm for a 1-cm-long AgGaS(2) crystal. Spectral noncritical phase matching within a specific tuning range was also investigated that permitted limited single-knob tuning (5.5-8.5 microm) of the difference-frequency generator. PMID:18305809

  18. Synthesis and characterization of a new layered organic-inorganic hybrid nickel(II) 1,4:5,8-naphthalenediimide bis-phosphonate, exhibiting canted antiferromagnetism, with T{sub c}{approx}21 K

    SciTech Connect

    Bauer, Elvira M. Bellitto, Carlo; Gomez Garcia, Carlos J. Righini, Guido

    2008-05-15

    A new Ni(II) layered hybrid organic-inorganic compound of formula Ni{sub 2}[(NDI-BP)(H{sub 2}O){sub 2}].2H{sub 2}O has been prepared in very mild conditions from N,N'-bis(2-phosphonoethyl)napthalene-1,4:5,8-tetracarboximide (NDI-BP ligand) and NiCl{sub 2}. The X-ray powder structure characterization of the title compound suggests a pillared layered organic-inorganic hybrid structure. The distance between the organic and inorganic layers has been found to be 17.8 A. The inorganic layers consist of corner sharing [NiO{sub 5}(H{sub 2}O)] octahedra and they are pillared by the diphosphonate groups. DC and AC magnetic measurements as a function of temperature and field indicate the presence of 2D antiferromagnetic exchange interactions between the nearest-neighbor Ni(II) ions below 100 K. A long-range magnetic ordering at T{sub c}{approx}21 K has been established and is attributed to the presence of spin canting. AC magnetic measurements as a function of temperature at different frequencies confirm the occurrence of the magnetic ordering temperature at T=21 K and the presence of a slight structural disorder in the title compound. - Graphical abstract: A new layered hybrid organic-inorganic Ni(II) N,N'-bis(2-phosphonoethyl)-naphthalene 1,4:5,8 tetracarboxydiimide complex has been synthesized and characterized. Magnetic measurements as a function of temperature and at different fields show that the compound is magnetically ordered below T{sub c}{approx}21 K.

  19. BMP4 and BMP7 Suppress StAR and Progesterone Production via ALK3 and SMAD1/5/8-SMAD4 in Human Granulosa-Lutein Cells.

    PubMed

    Zhang, Han; Klausen, Christian; Zhu, Hua; Chang, Hsun-Ming; Leung, Peter C K

    2015-11-01

    Adequate production of progesterone by the corpus luteum is critical to the successful establishment of pregnancy. In animal models, bone morphogenetic protein (BMP) 4 and BMP7 have been shown to suppress either basal or gonadotropin-induced progesterone production, depending on the species examined. However, the effects of BMP4 and BMP7 on progesterone production in human granulosa cells are unknown. In the present study, we used immortalized (SVOG) and primary human granulosa-lutein cells to investigate the effects of BMP4 and BMP7 on steroidogenic acute regulatory protein (StAR) expression and progesterone production and to examine the underlying molecular mechanism. Treatment of primary and immortalized human granulosa cells with recombinant BMP4 or BMP7 decreased StAR expression and progesterone accumulation. In SVOG cells, the suppressive effects of BMP4 and BMP7 on StAR expression were blocked by pretreatment with inhibitors of activin receptor-like kinase (ALK)2/3/6 (dorsomorphin) or ALK2/3 (DMH1) but not ALK4/5/7 (SB-431542). Moreover, small interfering RNA-mediated depletion of ALK3, but not ALK2 or ALK6, reversed the effects of BMP4 and BMP7 on StAR expression. Likewise, BMP4- and BMP7-induced phosphorylation of SMAD 1/5/8 was reversed by treatment with DMH1 or small interfering RNA targeting ALK3. Knockdown of SMAD4, the essential common SMAD for BMP/TGF-β signaling, abolished the effects of BMP4 and BMP7 on StAR expression. Our results suggest that BMP4 and BMP7 down-regulate StAR and progesterone production via ALK3 and SMAD1/5/8-SMAD4 signaling in human granulosa-lutein cells.

  20. Decision Making: The Toughest Job in the World

    ERIC Educational Resources Information Center

    Bullis, Robert V.

    1977-01-01

    The four phases in rational decision-making are (1) diagnosis, (2) discovering alternative solutions, (3) analyzing and comparing alternatives, and (4) selecting the proper alternative or plan to follow. (Author)