Science.gov

Sample records for 50th 75th 90th

  1. Standing adult human phantoms based on 10th, 50th and 90th mass and height percentiles of male and female Caucasian populations

    NASA Astrophysics Data System (ADS)

    Cassola, V. F.; Milian, F. M.; Kramer, R.; de Oliveira Lira, C. A. B.; Khoury, H. J.

    2011-07-01

    Computational anthropomorphic human phantoms are useful tools developed for the calculation of absorbed or equivalent dose to radiosensitive organs and tissues of the human body. The problem is, however, that, strictly speaking, the results can be applied only to a person who has the same anatomy as the phantom, while for a person with different body mass and/or standing height the data could be wrong. In order to improve this situation for many areas in radiological protection, this study developed 18 anthropometric standing adult human phantoms, nine models per gender, as a function of the 10th, 50th and 90th mass and height percentiles of Caucasian populations. The anthropometric target parameters for body mass, standing height and other body measures were extracted from PeopleSize, a well-known software package used in the area of ergonomics. The phantoms were developed based on the assumption of a constant body-mass index for a given mass percentile and for different heights. For a given height, increase or decrease of body mass was considered to reflect mainly the change of subcutaneous adipose tissue mass, i.e. that organ masses were not changed. Organ mass scaling as a function of height was based on information extracted from autopsy data. The methods used here were compared with those used in other studies, anatomically as well as dosimetrically. For external exposure, the results show that equivalent dose decreases with increasing body mass for organs and tissues located below the subcutaneous adipose tissue layer, such as liver, colon, stomach, etc, while for organs located at the surface, such as breasts, testes and skin, the equivalent dose increases or remains constant with increasing body mass due to weak attenuation and more scatter radiation caused by the increasing adipose tissue mass. Changes of standing height have little influence on the equivalent dose to organs and tissues from external exposure. Specific absorbed fractions (SAFs) have also

  2. [World War II 50th Anniversary.

    ERIC Educational Resources Information Center

    Johnson, Jeniffer, Ed.

    1991-01-01

    This edition of "Loblolly," a periodical published by Texas high school students, commemorates the 50th anniversary of World War II. The volume features remembrances of the War by veterans of Panola County, Texas. In addition to transcriptions of conversations with veterans, reproductions of photographs--some from the war period, some from more…

  3. 50th JANNAF Propulsion Meeting. Volume 1

    NASA Technical Reports Server (NTRS)

    Eggleston, Debra S. (Editor)

    2001-01-01

    This volume, the first of two volumes, is a collection of 29 unclassified/unlimited-distribution papers which were presented at the 50th Joint Army-Navy-NASA-Air Force (JANNAF) Propulsion Meeting, held 11-13 July 2001 at the Salt Lake City Marriott Hotel in Salt Lake City, Utah.

  4. ESO 50th Anniversary Gala Dinner

    NASA Astrophysics Data System (ADS)

    Sirey, R.

    2012-12-01

    To formally mark the 50th anniversary of the signing of the ESO Convention, a gala dinner was held in the Munich Residenz. A brief report of the event is presented and the speeches are reproduced. The speakers were the President of the Council, Xavier Barcons; the German Minister for Education and Research, Prof. Dr Annette Schavan; the Bavarian State Minister for Science, Research and the Arts, Dr Wolfgang Heubisch; physics Nobel Laureate, Brian Schmidt; the current Director General, Tim de Zeeuw and the Chilean Minister of Foreign Affairs, Alfredo Moreno Charme.

  5. The 50th Annual Maize Genetics Conference

    SciTech Connect

    Cone, Karen

    2014-03-26

    The 50th Annual Maize Genetics Conference was held February 27 - March 2, 2008 at the Marriott Wardman Park Hotel in Washington, D.C. As the golden anniversary of the Conference and coinciding with the release of a draft of the maize genome sequence, this was a special meeting. To publicize this unique occasion, meeting organizers hosted a press conference, which was attended by members of the press representing science and non-science publications, and an evening reception at the Smithsonian National Museum of Natural History, where the draft sequence was announced and awards were presented to Dr. Mary Clutter and Senator Kit Bond to thank them for their outstanding contributions to maize genetics and genomics research. As usual, the Conference provided an invigorating forum for exchange of recent research results in many areas of maize genetics, e.g., cytogenetics, development, molecular genetics, transposable element biology, biochemical genetics, and genomics. Results were shared via both oral and poster presentations. Invited talks were given by four distinguished geneticists: Vicki Chandler, University of Arizona; John Doebley, University of Wisconsin; Susan Wessler, University of Georgia; and Richard Wilson, Washington University. There were 46 short talks and 241 poster presentations. The Conference was attended by over 500 participants. This included a large number of first-time participants in the meeting and an increasingly visible presence by individuals from underrepresented groups. Although we do not have concrete counts, there seem to be more African American, African and Hispanic/Latino attendees coming to the meeting than in years past. In addition, this meeting attracted many participants from outside the U.S. Student participation continues to be hallmark of the spirit of free exchange and cooperation characteristic of the maize genetics community. With the generous support provided by DOE, USDA NSF, and corporate/private donors, organizers were

  6. 76 FR 26923 - 50th Anniversary of the Freedom Rides

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... From the Federal Register Online via the Government Publishing Office ] Vol. 76 Monday, No. 89 May 9, 2011 Part V The President Proclamation 8668--50th Anniversary of the Freedom Rides #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 76, No. 89 / Monday, May 9, 2011 / Presidential Documents#0;#0; #0; #0;Title 3-- #0;The President ]...

  7. 78 FR 13396 - 90th Meeting: RTCA Special Committee 159, Global Positioning Systems (GPS)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... Federal Aviation Administration 90th Meeting: RTCA Special Committee 159, Global Positioning Systems (GPS... Notice of RTCA Special Committee 159, RTCA Special Committee 159, Global Positioning Systems (GPS... Special Committee 159, Global Positioning Systems (GPS). DATES: The meeting will be held March 12-15,...

  8. Relativistic correlating basis sets for actinide atoms from 90Th to 103Lr.

    PubMed

    Noro, Takeshi; Sekiya, Masahiro; Osanai, You; Koga, Toshikatsu; Matsuyama, Hisashi

    2007-12-01

    For 14 actinide atoms from (90)Th to (103)Lr, contracted Gaussian-type function sets are developed for the description of correlations of the 5f, 6d, and 7s electrons. Basis sets for the 6d orbitals are also prepared, since the orbitals are important in molecular environments despite their vacancy in the ground state of some actinides. A segmented contraction scheme is employed for the compactness and efficiency. Contraction coefficients and exponents are so determined as to minimize the deviation from accurate natural orbitals of the lowest term arising from the 5f(n-1)6d(1)7s(2) configuration. The spin-free relativistic effects are considered through the third-order Douglas-Kroll approximation. To test the present correlating sets, all-electron calculations are performed on the ground state of (90)ThO molecule. The calculated spectroscopic constants are in excellent agreement with experimental values. PMID:17508413

  9. 33 CFR Appendix A to Part 209 - Public Law 90-483, 90th Congress, S. 3710, August 13, 1968

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Public Law 90-483, 90th Congress...—Public Law 90-483, 90th Congress, S. 3710, August 13, 1968 An act authorizing the construction, repair... bodies at water resources development projects authorized for construction under the Secretary of...

  10. 33 CFR Appendix A to Part 209 - Public Law 90-483, 90th Congress, S. 3710, August 13, 1968

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Public Law 90-483, 90th Congress...—Public Law 90-483, 90th Congress, S. 3710, August 13, 1968 An act authorizing the construction, repair... bodies at water resources development projects authorized for construction under the Secretary of...

  11. The Narrabri Stellar Intensity Interferometer: a 50th birthday tribute

    NASA Astrophysics Data System (ADS)

    Tuthill, Peter G.

    2014-07-01

    This year marks the 50th anniversary since the first scientific measurements were produced with the Narrabri Stellar Intensity Interferometer, which was constructed in the early 1960's by Robert Hanbury Brown and Richard Twiss. A collaboration between the Universities of Sydney and Manchester, the interferometer was the culmination of a series of experiments which pioneered the technique of intensity interferometry. The immediate controversy surrounding the quantum implications of the technique enveloped some of the most eminent physicists of the day, sparking a debate about nonlocal effects and optical coherence. A full explanation of the workings of the intensity interferometer in a quantum context was finally put forward by Roy Glauber, ultimately earning him the 2005 Nobel Prize in Physics. The intensity interferometer rekindled the field of high resolution stellar imaging, which had been extinguished for a half century (following the failure of Pease's 50-foot beam on Mt Wilson), while delivering the first ever measurements of the sizes of normal stars - establishing an effective temperature scaling relationship which has underpinned stellar astronomy for 50 years. This directly paved the way for the next generation of Michelson Stellar Interferometers. Intensity interferometry itself has found application in several fields (notably particle physics), and plans are in active development for modern reprises within stellar interferometry. However undoubtedly the greatest legacy lies in the Hanbury Brown Twiss (HBT) effect being the foundational experiment for what is now known as Quantum Optics - a field which underpins a huge sector of the technology which enables our modern world. This invited review discuses the development of the interferometer, including the controversy that its underlying principles generated within the contemporary physics community. The core scientific output generated by the instrument is presented, together with the impact of the

  12. AFTI/F-16 50th flight team photo

    NASA Technical Reports Server (NTRS)

    1983-01-01

    An early (1983) photograph of the AFTI F-16 team, commemorating the aircraft's 50th flight. It shows the initial configuration and paint finish of the AFTI F-16, as well as the forward mounted canards and the spin chute. During the 1980s and 1990s, NASA and the U.S. Air Force participated in a joint program to integrate and demonstrate new avionics technologies to improve close air support capabilities in next-generation aircraft. The testbed aircraft, seen here in flight over the desert at NASA's Dryden Flight Research Center, Edwards, California, was called the Advanced Fighter Technology Integration (AFTI) F-16. The tests demonstrated technologies to improve navigation and the pilot's ability to find and destroy enemy ground targets day or night, including adverse weather. The aircraft--an F-16A Fighting Falcon (Serial #75-0750)--underwent numerous modifications. A relatively low-cost testbed, it evaluated the feasability of advanced, intergrated-sensor, avionics, and flight control technologies. During the first phase of the AFTI/F-16 program, which began in 1983, the aircraft demonstrated voice-actuated commands, helmet-mounted sights, flat turns, and selective fuselage pointing using forward-mounted canards and a triplex digital flight control computer system. The second phase of research, which began in the summer of 1991, demonstrated advanced technologies and capabilities to find and destroy ground targets day or night, and in adverse weather while using maneuverability and speed at low altitude. This phase was known as the close air support and battlefield air interdiction (CAS/BAI) phase. Finally, the aircraft was used to assess the Automatic Ground Collision Avoidance System (Auto - GCAS), a joint project with the Swedish Government. For these tests, the pilot flew the aircraft directly toward the ground, simulating a total loss of control. The GCAS was designed to take command in such emergencies and bring the aircraft back to level flight. The AFTI F

  13. 75 FR 33995 - Safety Zone; Michigan Orthopaedic Society 50th Anniversary Fireworks, Lake Huron, Mackinac Island...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Michigan Orthopaedic Society 50th... Society 50th Anniversary Fireworks display, June 19, 2010. This temporary safety zone is necessary to... vessels during the setup and launching of fireworks in conjunction with the Michigan Orthopaedic...

  14. 50th Yearbook of the National Reading Conference (Scottsdale, Arizona, December 2000)

    ERIC Educational Resources Information Center

    Hoffman, James V., Ed.; Schallert, Diane L., Ed.; Fairbanks, Colleen M., Ed.; Worthy, Jo, Ed.; Maloch, Beth, Ed.

    2001-01-01

    At the 2000 conference in Scottsdale, Arizona, the National Reading Conference celebrated its 50th anniversary, and with this issue, the editors offer to the readership the "50th Yearbook" of the conference. This Yearbook begins with a preface and presents profiles of two awardees, Lee Gunderson and Michael Pressley. Included in this Yearbook are…

  15. 3 CFR 8668 - Proclamation 8668 of May 3, 2011. 50th Anniversary of the Freedom Rides

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8668 of May 3, 2011. 50th Anniversary of the Freedom Rides 8668 Proclamation 8668 Presidential Documents Proclamations Proclamation 8668 of May 3, 2011 Proc. 8668 50th Anniversary of the Freedom RidesBy the President of the United States of America A Proclamation Fifty years ago,...

  16. 3 CFR 8631 - Proclamation 8631 of February 28, 2011. 50th Anniversary of the Peace Corps

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 3 The President 1 2012-01-01 2012-01-01 false Proclamation 8631 of February 28, 2011. 50th Anniversary of the Peace Corps 8631 Proclamation 8631 Presidential Documents Proclamations Proclamation 8631 of February 28, 2011 Proc. 8631 50th Anniversary of the Peace CorpsBy the President of the United States of America A Proclamation In...

  17. A tribute to Dr. Frank I Tovey on his 90th birthday.

    PubMed

    Ma, Lian-Sheng

    2011-08-21

    This paper pays a tribute to Dr. Frank I Tovey on his 90th birthday which happens on September 1, 2011, and briefly describes the major findings in his research career and contributions as follows. The geographical prevalence of duodenal ulceration is related to staple diets. Unrefined wheat and maize, soya, certain pulses and millets are associated with a low prevalence while refined wheat, maize and rice, yams, cassava and green banana with a high prevalence. Predominant foodstuffs from low prevalence areas are ulceroprotective in rat peptic ulcer models. The protective activity lies in the lipid fraction present in these foodstuffs. The lipid fraction also promotes ulcer healing, is active both orally and intramuscularly and is ulceroprotective against non-steroidal anti-inflammatory drugs (NSAIDs). The phospholipids and phytosterols present in the lipid have been identified to be responsible for this protective activity. The combination of phospholipids and phytosterols may be of value in the prevention and treatment of duodenal ulceration and protection against the ulcerogenic effect of NSAIDs. PMID:21987600

  18. 75 FR 29658 - Safety Zone; America's Discount Tire 50th Anniversary, Fireworks Display, South Lake Tahoe, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; America's Discount Tire 50th Anniversary... support of America's Discount Tire 50th Anniversary Fireworks Display. This safety zone is established to... Discount Tire will sponsor their 50th Anniversary Celebration Fireworks Display on July 11 and 13, 2010,...

  19. 3 CFR 8829 - Proclamation 8829 of May 25, 2012. Commemoration of the 50th Anniversary of the Vietnam War

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the 50th Anniversary of the Vietnam War 8829 Proclamation 8829 Presidential Documents Proclamations Proclamation 8829 of May 25, 2012 Proc. 8829 Commemoration of the 50th Anniversary of the Vietnam WarBy the President of the United States of America A Proclamation As we observe the 50th anniversary of the...

  20. 78 FR 53235 - 50th Anniversary of the March on Washington for Jobs and Freedom

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    .... (Presidential Sig.) [FR Doc. 2013-21189 Filed 8-27-13; 11:15 am] Billing code 3295-F3 ... Documents#0;#0; ] Proclamation 9004 of August 23, 2013 50th Anniversary of the March on Washington for Jobs... remember that the March on Washington was a demonstration for jobs as well as freedom. The coalition...

  1. 77 FR 51473 - Safety Zone; Bostock 50th Anniversary Fireworks, Long Island Sound; Manursing Island, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Bostock 50th Anniversary Fireworks, Long... is establishing a temporary safety zone on the navigable waters of Long Island Sound in the vicinity... all vessels from a portion of Long Island Sound before, during, and immediately after the...

  2. 77 FR 34894 - Safety Zone; Bostock 50th Anniversary Fireworks, Long Island Sound; Manursing Island, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Bostock 50th Anniversary Fireworks, Long.... SUMMARY: The Coast Guard proposes to establish a temporary safety zone on the navigable waters of Long.... This rule is intended to restrict all vessels from a portion of Long Island Sound before, during,...

  3. Frontiers: Research Highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    DOE R&D Accomplishments Database

    1996-01-01

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  4. Frontiers: Research highlights 1946-1996 [50th Anniversary Edition. Argonne National Laboratory

    SciTech Connect

    1996-12-31

    This special edition of 'Frontiers' commemorates Argonne National Laboratory's 50th anniversary of service to science and society. America's first national laboratory, Argonne has been in the forefront of U.S. scientific and technological research from its beginning. Past accomplishments, current research, and future plans are highlighted.

  5. Celebrating the 50th Anniversary of the "Merrill-Palmer Quarterly"

    ERIC Educational Resources Information Center

    Ladd, Gary W.

    2004-01-01

    The academic year 2004-2005 marks the 50th anniversary of the "Merrill-Palmer Quarterly: A Journal of Developmental Psychology." This occasion provides an opportunity to celebrate the journal's heritage, its long history of scholarly contributions to the human developmental sciences, and its current and future mission as a purveyor of scientific…

  6. The State of the World's Children, 1996 (50th Anniversary Issue).

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This special issue of "The State of the World's Children" marks the 50th anniversary year of UNICEF and its work on behalf of children. Chapter 1 examines how wars and civil conflicts are taking an enormous toll on children. The chapter outlines a proposed anti-war agenda as a vital step to prevent and alleviate the suffering of children in armed…

  7. Digest of Education Statistics 2014, 50th Edition. NCES 2016-006

    ERIC Educational Resources Information Center

    Snyder, Thomas D.; de Brey, Cristobal; Dillow, Sally A.

    2016-01-01

    The 2014 edition of the "Digest of Education Statistics" is the 50th in a series of publications initiated in 1962. The Digest has been issued annually except for combined editions for the years 1977-78, 1983-84, and 1985-86. Its primary purpose is to provide a compilation of statistical information covering the broad field of American…

  8. 75 FR 50843 - 75th Anniversary of the Social Security Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... From the Federal Register Online via the Government Publishing Office #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 75, No. 159 / Wednesday, August 18, 2010 / Presidential Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8546 of August 13, 2010 75th Anniversary of the Social Security Act By the President of the United States...

  9. 3 CFR 8613 - Proclamation 8613 of December 6, 2010. 50th Anniversary of the Arctic National Wildlife Refuge

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8613 of December 6, 2010. 50th Anniversary of the Arctic National Wildlife Refuge 8613 Proclamation 8613 Presidential Documents Proclamations Proclamation 8613 of December 6, 2010 Proc. 8613 50th Anniversary of the Arctic National Wildlife RefugeBy the President of the United States...

  10. 77 FR 21893 - Safety Zone; International Bridge 50th Anniversary Celebration Fireworks, St Mary's River, U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; International Bridge 50th Anniversary... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting, but you may.... 165.T09-0200 to read as follows: Sec. 165.T09-0200 Safety Zone International Bridge 50th...

  11. 3 CFR 8533 - Proclamation 8533 of June 10, 2010. 90th Anniversary of the Department of Labor Women’s Bureau, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 3 The President 1 2011-01-01 2011-01-01 false Proclamation 8533 of June 10, 2010. 90th Anniversary of the Department of Labor Womenâs Bureau, 2010 8533 Proclamation 8533 Presidential Documents Proclamations Proclamation 8533 of June 10, 2010 Proc. 8533 90th Anniversary of the Department of Labor Women’s Bureau, 2010By the President of the...

  12. Highlights from the 50th Seminar of the Korean Society of Gastrointestinal Endoscopy

    PubMed Central

    Kim, Eun Young; Choi, Il Ju; Kwon, Kwang An; Ryu, Ji Kon; Dong, Seok Ho

    2014-01-01

    The July issue of Clinical Endoscopy deals with selected articles covering the state-of-the-art lectures delivered during the 50th seminar of the Korean Society of Gastrointestinal Endoscopy (KSGE) on March 30, 2014, highlighting educational contents pertaining to either diagnostic or therapeutic gastrointestinal (GI) endoscopy, which contain fundamental and essential points in GI endoscopy. KSGE is very proud of its seminar, which has been presented twice a year for the last 25 years, and hosted more than 3,500 participants at the current meeting. KSGE seminar is positioned as one of premier state-of-the-art seminars for endoscopy, covering topics for novice endoscopists and advanced experts, as well as diagnostic and therapeutic endoscopy. The 50th KSGE seminar consists of more than 20 sessions, including a single special lecture, concurrent sessions for GI endoscopy nurses, and sessions exploring new technologies. Nine articles were selected from these prestigious lectures, and invited for publication in this special issue. This introductory review, prepared by the editors of Clinical Endoscopy, highlights core contents divided into four sessions: upper GI tract, lower GI tract, pancreatobiliary system, and other specialized topic sessions, including live demonstrations and hands-on courses. PMID:25133113

  13. Injury risk curves for the WorldSID 50th male dummy.

    PubMed

    Petitjean, Audrey; Trosseille, Xavier; Petit, Philippe; Irwin, Annette; Hassan, Joe; Praxl, Norbert

    2009-11-01

    The development of the WorldSID 50th percentile male dummy was initiated in 1997 by the International Organisation for Standardisation (ISO/SC12/TC22/WG5) with the objective of developing a more biofidelic side impact dummy and supporting the adoption of a harmonised dummy into regulations. More than 45 organizations from all around the world have contributed to this effort including governmental agencies, research institutes, car manufacturers and dummy manufacturers. The first production version of the WorldSID 50th male dummy was released in March 2004 and demonstrated an improved biofidelity over existing side impact dummies. Full scale vehicle tests covering a wide range of side impact test procedures were performed worldwide with the WorldSID dummy. However, the vehicle safety performance could not be assessed due to lack of injury risk curves for this dummy. The development of these curves was initiated in 2004 within the framework of ISO/SC12/TC22/WG6 (Injury criteria). In 2008, the ACEA- Dummy Task Force (TFD) decided to contribute to this work and offered resources for a project manager to coordinate of the effort of a group of volunteer biomechanical experts from international institutions (ISO, EEVC, VRTC/NHTSA, JARI, Transport Canada), car manufacturers (ACEA, Ford, General Motors, Honda, Toyota, Chrysler) and universities (Wayne State University, Ohio State University, John Hopkins University, Medical College of Wisconsin) to develop harmonized injury risk curves. An in-depth literature review was conducted. All the available PMHS datasets were identified, the test configurations and the quality of the results were checked. Criteria were developed for inclusion or exclusion of PMHS tests in the development of the injury risk curves. Data were processed to account for differences in mass and age of the subjects. Finally, injury risk curves were developed using the following statistical techniques, the certainty method, the Mertz/Weber method, the

  14. 50th Year Anniversary of Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University.

    PubMed

    Lertakyamanee, Jariya

    2016-05-01

    Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, has started to be a formal anesthesia division, divided from division of Surgery in 1965; hence our 50th year anniversary in 2015. Research is now a priority and mandatory mission, according to the vision of Mahidol University. Second mission is to teach and train, and we produce the highest number of states-of-the-art anesthesiologists and anesthetic nurses each year Curriculum and training are being continuously improved. From a small unit, now it is one of the largest departments and extends the service, our third mission, to more than only in the operating theaters. We look after pre-anesthesia assessment, inside and outside operating room anesthesia, post-operative pain relief Intensive Care Unit, and chronic pain management. The number of patients and their diseases increase; so do the complexities of surgeries. There are tremendous changes in drugs and equipment. There is the fourth mission on administration, IT and resource management. And the fifth mission which is corporate social responsibility. However, we still believe that compassion, responsibility and integrity are most important. We have taught and tried to live by the teaching of HRH the King's Father. And these will contribute to our progress and shine in the next 50 years. PMID:27501620

  15. 77 FR 33094 - Safety Zone; International Bridge 50th Anniversary Celebration Fireworks, St. Mary's River, U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; International Bridge 50th Anniversary..., Sault Sainte Marie, MI; in the Federal Register (77 FR 21893). We received 1 public submission... Locks, Sault Sainte Marie, MI; in the Federal Register (76 FR 22064). We received 1 public...

  16. Symposium--Perspectives on Motivation for Second Language Learning on the 50th Anniversary of Gardner & Lambert (1959)

    ERIC Educational Resources Information Center

    MacIntyre, Peter

    2010-01-01

    With the 50th anniversary of Robert C. Gardner and Wallace Lambert's seminal paper "Motivational variables in second language acquisition" (Gardner & Lambert 1959), we paused to reflect on the contributions the work has inspired and the state of the art in the study of motivation research.

  17. NRAO Salutes Past, Looks to Future In 50th-Anniversary Science Meeting

    NASA Astrophysics Data System (ADS)

    2007-06-01

    Radio telescopes now in operation or under construction will be indispensible to scientists wrestling with the big, unanswered questions of 21st-Century astrophysics. That was the conclusion of a wide-ranging scientific meeting held in Charlottesville, Virginia, June 18-21, to mark the 50th anniversary of the National Radio Astronomy Observatory (NRAO). 1957 Dedication Dedication of NRAO, 17 October 1957. Left to right: R.M. Emberson, L.V. Berkner, G.A. Nay, J.W. Findlay (seated in front of 140ft telescope model), N.L. Ashton, D.S. Heeschen, H. Hockenberry. CREDIT: NRAO/AUI/NSF Click on Image for Larger File ALMA Artist's conception of completed ALMA. CREDIT: NRAO/AUI/ESO Click on Image for Larger File (2.4 MB) Nearly 200 scientists from around the world heard presentations about the frontiers of astrophysics and how the challenges at those frontiers will be met. In specialties as disparate as seeking the nature of the mysterious Dark Energy that is speeding the Universe's expansion to unraveling the details of how stars and planets are formed, more than 70 presenters looked toward future research breakthroughs. "NRAO's telescopes have made landmark contributions to the vast explosion of astronomical knowledge of the past half- century, and we look eagerly to making even more important contributions in the coming decades," said Fred K.Y. Lo, NRAO's director. Over the four days of the meeting, discussions ranged from recollections of radio astronomy's pioneering days of vacuum-tube equipment and paper chart recorders to the design of telescopes that will produce amounts of data that will strain today's computers. Presenters pointed out that, in the coming decades, radio telescope observations will advance not only astronomy but also fields of basic physics such as gravitational radiation, particle physics, and the fundamental physical constants. "This meeting provided a great overview of where astrophysics stands today and where the challenges and opportunities of

  18. The 50th Anniversary of the First International Conference on Permafrost

    NASA Astrophysics Data System (ADS)

    Brown, J.

    2013-12-01

    This year marks the 50th anniversary of the First International Conference on Permafrost (ICOP) that was held at Purdue University on 11-15 November 1963. The conference was a historic event in that it brought together for the first time the leading researchers and practitioners from North America and other countries that had diverse interests and activities in the study and applications of perennially frozen ground, cold regions engineering and related laboratory investigations. The 285 registered participants represented engineers, researchers, manufacturers and builders from the USA (231), Canada (42), the USSR (5), Sweden (3) and Argentina, Austria, Great Britain, Japan, Norway, Poland, Switzerland, and West Germany. The conference was organized by the Building Research Advisory Board of the U.S. National Academy of Sciences-National Research Council (NAS-NRC). The carefully edited volume, published in 1966 by the NAS, is considered to be the first multi-national, English-language collection of papers devoted entirely to permafrost topics. The 100 published papers followed closely the actual conference venue and panel discussions: soils and vegetation (9), massive ground ice (10), geomorphology (16), phase equilibrium and transition (8), thermal aspects (8), physico-mechanical properties (7), exploration and site selection (11), sanitary and hydraulic engineering (14), and earthwork and foundations (17). This 1963 Purdue conference essentially broke the 'ice' between East and West permafrost researchers and set the stage for the Second ICOP that was held in 1973 in Yakutsk, Siberia, and represented the first large international conference held in the restricted area of Siberia. All subsequent conferences maintained the interdisciplinary principles set forth at Purdue: two more in the United States (Fairbanks 1983, 2008), two in Canada (Edmonton 1978, Yellowknife 1998), and one in Trondheim, Norway (1988), Beijing, China (1993), and Zurich, Switzerland (2003

  19. Echo-enabled harmonics up to the 75th order from precisely tailored electron beams

    NASA Astrophysics Data System (ADS)

    Hemsing, E.; Dunning, M.; Garcia, B.; Hast, C.; Raubenheimer, T.; Stupakov, G.; Xiang, D.

    2016-08-01

    The production of coherent radiation at ever shorter wavelengths has been a long-standing challenge since the invention of lasers and the subsequent demonstration of frequency doubling. Modern X-ray free-electron lasers (FELs) use relativistic electrons to produce intense X-ray pulses on few-femtosecond timescales. However, the shot noise that seeds the amplification produces pulses with a noisy spectrum and limited temporal coherence. To produce stable transform-limited pulses, a seeding scheme called echo-enabled harmonic generation (EEHG) has been proposed, which harnesses the highly nonlinear phase mixing of the celebrated echo phenomenon to generate coherent harmonic density modulations in the electron beam with conventional lasers. Here, we report on a demonstration of EEHG up to the 75th harmonic, where 32 nm light is produced from a 2,400 nm laser. We also demonstrate that individual harmonic amplitudes are controlled by simple adjustment of the phase mixing. Results show the potential of laser-based manipulations to achieve precise control over the coherent spectrum in future X-ray FELs for new science.

  20. The 50th Anniversary of the International Indian Ocean Expedition: An Update on Current Planning Efforts and Progress

    NASA Astrophysics Data System (ADS)

    Hood, Raleigh; D'Adamo, Nick; Burkill, Peter; Urban, Ed; Bhikajee, Mitrasen

    2014-05-01

    The International Indian Ocean Expedition (IIOE) was one of the greatest international, interdisciplinary oceanographic research efforts of all time. Planning for the IIOE began in 1959 and the project officially continued through 1965, with forty-six research vessels participating under fourteen different flags. The IIOE motivated an unprecedented number of hydrographic surveys (and repeat surveys) over the course of the expedition covering the entire Indian Ocean basin. And it was an interdisciplinary endeavor that embraced physical oceanography, chemical oceanography, meteorology, marine biology, marine geology and geophysics. The end of 2015 will mark the 50th Anniversary of the completion of the IIOE. In the 50 years since the IIOE three fundamental changes have taken place in ocean science. The first is the deployment of a broad suite of oceanographic sensors on satellites that have dramatically improved the characterization of both physical and biological oceanographic variability. The second is the emergence of new components of the ocean observing system, most notably remote sensing and Argo floats. And the third is the development of ocean modeling in all its facets from short-term forecasting to seasonal prediction to climate projections. These advances have revolutionized our understanding of the global oceans, including the Indian Ocean. Compared to the IIOE era, we now have the capacity to provide a much more integrated picture of the Indian Ocean, especially if these new technologies can be combined with targeted and well-coordinated in situ measurements. In this presentation we report on current efforts to motivate an IIOE 50th Anniversary Celebration (IIOE-2). We envision this IIOE-2 as a 5-year expedition and effort beginning in 2015 and continuing through to 2020. An important objective of our planning efforts is assessing ongoing and planned research activities in the Indian Ocean in the 2015 to 2020 time frame, with the goal of embracing and

  1. X-ray production cross sections at incident photon energies across the M{sub i} (i=1-5) edges of {sub 90}Th

    SciTech Connect

    Kaur, Rajnish; Shehla,; Kumar, Anil; Puri, Sanjiv

    2015-08-28

    The X-ray production cross sections for the M{sub k} (k= ξ, δ, α, β, ζ, γ, m{sub 1}, m{sub 2}) groups of X-rays have been evaluated at incident photon energies across the M{sub i} (i =1-5) edges of {sub 90}Th using the relativistic Hartree-Fock-Slater model based photoionisation cross sections and recently reported values of the M-shell X-ray emission rates, fluorescence and Coster Kronig yields. Further, the energies of the prominent (M{sub i}-S{sub j}) (S{sub j}=N{sub j}, O{sub j} and i =1-3, j =1-7) resonant Raman scattered (RRS) peaks at different incident photon energies have also been evaluated using the neutral-atom electron binding energies (E{sub sj}) based on the relaxed orbital relativistic Hartree-Fock-Slater model.

  2. Human Behavioral Pharmacology, Past, Present, and Future: Symposium Presented at the 50th Annual Meeting of the Behavioral Pharmacology Society

    PubMed Central

    Comer, Sandra D.; Bickel, Warren K.; Yi, Richard; de Wit, Harriet; Higgins, Stephen T.; Wenger, Galen R.; Johanson, Chris-Ellyn; Kreek, Mary Jeanne

    2010-01-01

    A symposium held at the 50th annual meeting of the Behavioral Pharmacology Society in May 2007 reviewed progress in the human behavioral pharmacology of drug abuse. Studies on drug self-administration in humans are reviewed that assessed reinforcing and subjective effects of drugs of abuse. The close parallels observed between studies in humans and laboratory animals using similar behavioral techniques have broadened our understanding of the complex nature of the pharmacological and behavioral factors controlling drug self-administration. The symposium also addressed the role that individual differences, such as gender, personality, and genotype play in determining the extent of self-administration of illicit drugs in human populations. Knowledge of how these factors influence human drug self-administration has helped validate similar differences observed in laboratory animals. In recognition that drug self-administration is but one of many choices available in the lives of humans, the symposium addressed the ways in which choice behavior can be studied in humans. These choice studies in human drug abusers have opened up new and exciting avenues of research in laboratory animals. Finally, the symposium reviewed behavioral pharmacology studies conducted in drug abuse treatment settings and the therapeutic benefits that have emerged from these studies. PMID:20664330

  3. Advanced optical correlation and digital methods for pattern matching—50th anniversary of Vander Lugt matched filter

    NASA Astrophysics Data System (ADS)

    Millán, María S.

    2012-10-01

    On the verge of the 50th anniversary of Vander Lugt’s formulation for pattern matching based on matched filtering and optical correlation, we acknowledge the very intense research activity developed in the field of correlation-based pattern recognition during this period of time. The paper reviews some domains that appeared as emerging fields in the last years of the 20th century and have been developed later on in the 21st century. Such is the case of three-dimensional (3D) object recognition, biometric pattern matching, optical security and hybrid optical-digital processors. 3D object recognition is a challenging case of multidimensional image recognition because of its implications in the recognition of real-world objects independent of their perspective. Biometric recognition is essentially pattern recognition for which the personal identification is based on the authentication of a specific physiological characteristic possessed by the subject (e.g. fingerprint, face, iris, retina, and multifactor combinations). Biometric recognition often appears combined with encryption-decryption processes to secure information. The optical implementations of correlation-based pattern recognition processes still rely on the 4f-correlator, the joint transform correlator, or some of their variants. But the many applications developed in the field have been pushing the systems for a continuous improvement of their architectures and algorithms, thus leading towards merged optical-digital solutions.

  4. 50th Anniversary of the first successful permanent pacemaker implantation in the United States: historical review and future directions.

    PubMed

    Beck, Hiroko; Boden, William E; Patibandla, Sushmitha; Kireyev, Dmitriy; Gutpa, Vipul; Campagna, Franklin; Cain, Michael E; Marine, Joseph E

    2010-09-15

    June 2010 marks the 50th anniversary of the first successful human cardiac pacemaker implantation in the United States. On June 6, 1960, in Buffalo, New York, Dr. William Chardack implanted a pacemaker, designed and built by Wilson Greatbatch, an electrical engineer and inventor, in a 77-year old man with complete atrioventricular block, extending the patient's life by 18 months. This landmark event ushered in a new era of implantable cardiac pacemakers with batteries and leads of high reliability and increasing durability. Over the past half century, the field of electrophysiology and implantable devices for the management of cardiac conduction disturbances has evolved dramatically. Today's pacemakers include increasingly complex features such as telemetry monitoring, auto programmability, and hemodynamic sensors. New-generation leads present a sophisticated design with improved geometry and steroid-eluting tips to reduce chronic inflammation, maintaining a low pacing threshold and high sensing capability. The lithium iodide battery remains the mainstay of implantable pacemaker systems, exhibiting a multiple-year lifespan, slow terminal decay, and a reduced size and cost of production. Although Greatbatch's first successful pacemaker implantation remains a seminal scientific contribution to modern cardiovascular disease management, emerging developments in this field may challenge its preeminence. Important challenges such as imaging compatibility, lead durability, and infection prevention are being addressed. Novel concepts such as leadless and biologic pacing are under active investigation. In conclusion, Greatbatch's historic achievement 50 years ago reminds us that technologic progress is timeless, as efforts to enhance clinical outcomes and the quality of life continue unimpeded into the 21st century. PMID:21391322

  5. Educating Black Librarians. Papers from the 50th Anniversary Celebration of the School of Library and Information Sciences, North Carolina Central University.

    ERIC Educational Resources Information Center

    Speller, Benjamin F., Jr., Ed.

    This document assembles 16 papers given at a 1989 symposium in honor of the 50th anniversary of the School of Library and Information Sciences at North Carolina Central University, Durham (NCCU). The papers examine the past, present, and future of the participation of African Americans in the field of library and information service. Titles…

  6. The Long Good-Bye: Why B. F. Skinner's "Verbal Behavior" Is Alive and Well on the 50th Anniversary of Its Publication

    ERIC Educational Resources Information Center

    Schlinger, Henry D.

    2008-01-01

    The year 2007 marked the 50th anniversary of the publication of B. F. Skinner's "Verbal Behavior", a book that by Skinner's own account was his most important. The received view, however, is that a devastating review by a young linguist not only rendered Skinner's interpretation of language moot but was also a major factor in ending the hegemony…

  7. Is the 90th Percentile Adequate? The Optimal Waist Circumference Cutoff Points for Predicting Cardiovascular Risks in 124,643 15-Year-Old Taiwanese Adolescents

    PubMed Central

    Ho, ChinYu; Chen, Hsin-Jen; Huang, Nicole; Yeh, Jade Chienyu; deFerranti, Sarah

    2016-01-01

    Adolescent obesity has increased to alarming proportions globally. However, few studies have investigated the optimal waist circumference (WC) of Asian adolescents. This study sought to establish the optimal WC cutoff points that identify a cluster of cardiovascular risk factors (CVRFs) among 15-year-old ethnically Chinese adolescents. This study was a regional population-based study on the CVRFs among adolescents who enrolled in all the senior high schools in Taipei City, Taiwan, between 2011 and 2014. Four cross-sectional health examinations of first-year senior high school (grade 10) students were conducted from September to December of each year. A total of 124,643 adolescents aged 15 (boys: 63,654; girls: 60,989) were recruited. Participants who had at least three of five CVRFs were classified as the high-risk group. We used receiver-operating characteristic curves and the area under the curve (AUC) to determine the optimal WC cutoff points and the accuracy of WC in predicting high cardiovascular risk. WC was a good predictor for high cardiovascular risk for both boys (AUC: 0.845, 95% confidence interval [CI]: 0.833–0.857) and girls (AUC: 0.763, 95% CI: 0.731–0.795). The optimal WC cutoff points were ≥78.9 cm for boys (77th percentile) and ≥70.7 cm for girls (77th percentile). Adolescents with normal weight and an abnormal WC were more likely to be in the high cardiovascular risk group (odds ratio: 3.70, 95% CI: 2.65–5.17) compared to their peers with normal weight and normal WC. The optimal WC cutoff point of 15-year-old Taiwanese adolescents for identifying CVRFs should be the 77th percentile; the 90th percentile of the WC might be inadequate. The high WC criteria can help health professionals identify higher proportion of the adolescents with cardiovascular risks and refer them for further evaluations and interventions. Adolescents’ height, weight and WC should be measured as a standard practice in routine health checkups. PMID:27389572

  8. Is the 90th Percentile Adequate? The Optimal Waist Circumference Cutoff Points for Predicting Cardiovascular Risks in 124,643 15-Year-Old Taiwanese Adolescents.

    PubMed

    Lee, Jason Jiunshiou; Ho, ChinYu; Chen, Hsin-Jen; Huang, Nicole; Yeh, Jade Chienyu; deFerranti, Sarah

    2016-01-01

    Adolescent obesity has increased to alarming proportions globally. However, few studies have investigated the optimal waist circumference (WC) of Asian adolescents. This study sought to establish the optimal WC cutoff points that identify a cluster of cardiovascular risk factors (CVRFs) among 15-year-old ethnically Chinese adolescents. This study was a regional population-based study on the CVRFs among adolescents who enrolled in all the senior high schools in Taipei City, Taiwan, between 2011 and 2014. Four cross-sectional health examinations of first-year senior high school (grade 10) students were conducted from September to December of each year. A total of 124,643 adolescents aged 15 (boys: 63,654; girls: 60,989) were recruited. Participants who had at least three of five CVRFs were classified as the high-risk group. We used receiver-operating characteristic curves and the area under the curve (AUC) to determine the optimal WC cutoff points and the accuracy of WC in predicting high cardiovascular risk. WC was a good predictor for high cardiovascular risk for both boys (AUC: 0.845, 95% confidence interval [CI]: 0.833-0.857) and girls (AUC: 0.763, 95% CI: 0.731-0.795). The optimal WC cutoff points were ≥78.9 cm for boys (77th percentile) and ≥70.7 cm for girls (77th percentile). Adolescents with normal weight and an abnormal WC were more likely to be in the high cardiovascular risk group (odds ratio: 3.70, 95% CI: 2.65-5.17) compared to their peers with normal weight and normal WC. The optimal WC cutoff point of 15-year-old Taiwanese adolescents for identifying CVRFs should be the 77th percentile; the 90th percentile of the WC might be inadequate. The high WC criteria can help health professionals identify higher proportion of the adolescents with cardiovascular risks and refer them for further evaluations and interventions. Adolescents' height, weight and WC should be measured as a standard practice in routine health checkups. PMID:27389572

  9. Effect of Anatomical Modeling on Space Radiation Dose Estimates: A Comparison of Doses for NASA Phantoms and 5th, 50th, and 95th Percentile UF Hybrid Phantoms

    NASA Technical Reports Server (NTRS)

    Bahadori, A.; VanBaalen, M.; Shavers, M.; Semones, E.; Dodge, C.; Bolch, W.

    2010-01-01

    The estimate of absorbed dose to individual organs of a space crewmember is affected by the geometry of the anatomical model of the astronaut used in the radiation transport calculation. For astronaut dosimetry, NASA currently uses the computerized anatomical male (CAM) and computerized anatomical female (CAF) stylized phantoms to represent astronauts in its operational radiation dose analyses. These phantoms are available in one size and in two body positions. In contrast, the UF Hybrid Adult Male and Female (UFHADM and UFHADF) phantoms have organ shapes based on actual CT data. The surfaces of these phantoms are defined by non-uniform rational B-spline surfaces, and are thus flexible in terms of body morphometry and extremity positioning. In this study, UFHADM and UFHADF are scaled to dimensions corresponding to 5th, 50th, and 95th percentile (PCTL) male and female astronauts. A ray-tracing program is written in Visual Basic 2008, which is then used to create areal density maps for dose points corresponding to various organs within the phantoms. The areal density maps, along with appropriate space radiation spectra, are input into the NASA program couplet HZETRN/BRYNTRN, and organ doses are calculated. The areal density maps selected tissues and organs of the 5th, 50th, and 95th PCTL male and female phantoms are presented and compared. In addition, the organ doses for the 5th, 50th, and 95th PCTL male and female phantoms are presented and compared to organ doses for CAM and CAF.

  10. Commemoration of the 90th anniversary of the birth of Andrei Dmitrievich Sakharov (Scientific session of the Physical Sciences Division, Russian Academy of Sciences, 25 May 2011)

    NASA Astrophysics Data System (ADS)

    2012-02-01

    On 25 May 2011, the scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS), devoted to the 90th anniversary of Andrei Dmitrievich Sakharov's birthday, was held at the conference hall of the Lebedev Physical Institute, RAS.The agenda of the session announced on the website www.gpad.ac.ru of the PSD RAS contains the following reports: (1) Mesyats G A (Lebedev Physical Institute, RAS, Moscow) "Introduction. Greetings"; (2) Ritus V I (Lebedev Physical Institute, RAS, Moscow) "A D Sakharov: personality and fate"; (3) Altshuler B L (Lebedev Physical Institute, RAS, Moscow) "Scientific and public legacy of A D Sakharov today"; (4) Ilkaev R I (Russian Federal Nuclear Center 'All-Russian Research Institute of Experimental Physics', Sarov, Nizhny Novgorod region) "The path of a genius: Sakharov at KB-11"; (5) Novikov I D (Astrocosmic Center, Lebedev Physical Institute, RAS, Moscow) "Wormholes and the multielement Universe"; (6) Azizov E A (National Research Centre 'Kurchatov Institute', Moscow) "Tokamaks: 60 years later"; (7) Kardashev N S (Astrocosmic Center, Lebedev Physical Institute, RAS, Moscow) "Cosmic interferometers"; (8) Lukash V I (Lebedev Physical Institute, RAS, Moscow) "From the cosmological model to the Hubble flux formation"; (9) Grishchuk L P (Shternberg State Astronomical Institute, Lomonosov Moscow State University, Moscow; School of Physics and Astronomy, Cardiff University, Cardiff, United Kingdom) "Cosmological Sakharov oscillations and quantum mechanics of the early Universe". Articles based on reports 2-4, 6, 8, and 9 are published below. The content of report 5 is close to papers "Multicomponent Universe and astrophysics of wormholes" by I D Novikov, N S Kardashev, A A Shatskii [Phys. Usp. 50 965 (2007)] and "Dynamic model of a wormhole and the Multiuniverse model" by A A Shatskii, I D Novikov, N S Kardashev [Phys. Usp. 51 457 (2008)]. The content of report 7 is close to the paper "Radioastron - a radio telescope

  11. 38 CFR 12.13 - Posting of notice of the provisions of Pub. L. No. 734, 75th Congress (38 U.S.C. 16-16j).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Posting of notice of the provisions of Pub. L. No. 734, 75th Congress (38 U.S.C. 16-16j). 12.13 Section 12.13 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS DISPOSITION OF VETERAN'S PERSONAL FUNDS AND EFFECTS Disposition of Veteran's Personal...

  12. Stream flow changes across North Carolina (USA) 1955-2012 with implications for environmental flow management

    NASA Astrophysics Data System (ADS)

    Meitzen, Kimberly M.

    2016-01-01

    This study examines changes in stream flow conditions across North Carolina, relates these changes to geomorphological conditions of rivers, and makes recommendations for environmental flow guidelines to conserve and protect riverine ecosystems. Monthly stream flow percentile metrics (90th, 75th, 50th, 25th, and 10th percentiles) are compared over two time periods (1955-1980 and 1984-2012) for 63 gages distributed statewide. The results showed that stream flow changes vary spatially by flow magnitude, ecoregion, basin, and temporally by months. The greatest changes involve decreases to the 10th, 25th, 50th, and 75th percentiles and the least amount of change is associated with 90th percentile flows. The spring and summer months of February through August have the greatest flow reductions, while September, November, and December exhibit magnitude increases for the 75th and 90th percentile flows. The Blue Ridge has the least amount of change, whereas the Piedmont and Coastal Plain have the greatest change. The few gages that do not show significant magnitude decreases to the 10th percentile flow are below major dams on the Neuse, Cape Fear, and Roanoke rivers. These same dammed rivers exhibit increases to the 90th percentile flows. The Tar River Basin, which is free of dams, shows opposite effects, with significant decreases to the 10th percentile flows and minimal changes to the 75th and 90th percentile flows. This study elucidates the importance of establishing environmental flow criteria that apply statewide across North Carolina. Sustainable environmental flow criteria need to be established that conserve seasonal patterns of flows, sustain low flows (from increases and decreases), and protect headwater and tributary accumulation areas from over-abstraction.

  13. MABAHISS/John Murray 50th Anniversary: Marine Science of the North West Indian Ocean and Adjacent Waters. Report of a Symposium on the Occasion of the 50th Anniversary of the MABAHISS/John Murray Expedition (1933/34) (Alexandria, Egypt, September 3-7, 1983). Unesco Reports in Marine Science, No. 31.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Div. of Marine Sciences.

    An international symposium was convened to celebrate the 50th anniversary of the John Murray Expedition to the Indian Ocean on board the Egyptian research vessel Mabahiss (1933-1934). This report describes the symposium and provides abstracts and syntheses of the papers presented in the various marine scientific disciplines covering the areas of…

  14. Summary of the Workshop on Molten Salt Reactor Technologies Commemorating the 50th Anniversary of the Startup of the Molten Salt Reactor Experiment

    SciTech Connect

    Betzler, Benjamin R; Mays, Gary T

    2016-01-01

    A workshop on Molten Salt Reactor (MSR) technologies commemorating the 50th anniversary of the Molten Salt Reactor Experiment (MSRE) was held at Oak Ridge National Laboratory on October 15 16, 2015. The MSRE represented a pioneering experiment that demonstrated an advanced reactor technology: the molten salt eutectic-fueled reactor. A multinational group of more than 130 individuals representing a diverse set of stakeholders gathered to discuss the historical, current, and future technical challenges and paths to deployment of MSR technology. This paper provides a summary of the key messages from this workshop.

  15. The dawn of open heart surgery: an overview of the symposium that celebrated the 50th anniversary of controlled cross circulation.

    PubMed

    DeWall, Richard

    2005-01-01

    At the 50th Anniversary of Open Heart Surgery symposium sponsored by the Lillehei Heart Institute of the University of Minnesota in October 2004, the following pioneers in open heart surgery development presented papers of historical interest: Drs. Peter Agre, Robert W. Anderson, William Baumgartner, Alain Carpentier, Aldo Casteneda, Randolph Chitwood, Jr., Denton Cooley, Fred Crawford, Michael DeBakey, Richard DeWall, Vincent Gott, Claude Lenfant, Floyd Loop, James Holler, Glen Nelson, Norman Shumway, Manny Villafana, Richard Weisel, and Sir Magdi Yacoub. PMID:16106145

  16. A report from the European Association for the Study of the Liver's 50th International Liver Congress (April 22-26 - Vienna, Austria).

    PubMed

    Rabasseda, X

    2015-04-01

    While Vienna's Prater park offers a varied selection of options, from theme parks to lush gardens and prairies to enjoy the sun, the nearby Messe Wien convention center was the focus of attention in April 2015 for all the scientists, researchers and clinicians interested in viral hepatitis, nonalcoholic steatohepatitis, hepatocellular carcinoma and a variety of other liver diseases. Treatments and potential new therapeutic strategies for these hepatopathies were discussed during the 50th International Liver Congress organized by the European Association for the Study of the Liver. Echoing epidemiological facts and a high social interest for hepatitis C virus infection, new findings with investigational and potential new therapies for the disease centered much of the attention at the conference. Nevertheless, new research was also reported related to potential improvements in how other liver diseases, particularly hepatitis B virus infection, hepatocellular carcinoma and a range of inflammatory and immune-mediated liver diseases, including rare hereditary diseases that should never be forgotten. PMID:26020068

  17. Thoracic response targets for a computational model: a hierarchical approach to assess the biofidelity of a 50th-percentile occupant male finite element model.

    PubMed

    Poulard, David; Kent, Richard W; Kindig, Matthew; Li, Zuoping; Subit, Damien

    2015-05-01

    Current finite element human thoracic models are typically evaluated against a limited set of loading conditions; this is believed to limit their capability to predict accurate responses. In this study, a 50th-percentile male finite element model (GHBMC v4.1) was assessed under various loading environments (antero-posterior rib bending, point loading of the denuded ribcage, omnidirectional pendulum impact and table top) through a correlation metric tool (CORA) based on linearly independent signals. The load cases were simulated with the GHBMC model and response corridors were developed from published experimental data. The model was found to be in close agreement with the experimental data both qualitatively and quantitatively (CORA ratings above 0.75) and the response of the thorax was overall deemed biofidelic. This study also provides relevant corridors and an objective rating framework that can be used for future evaluation of thoracic models. PMID:25681717

  18. Introduction to the special issue: 50th anniversary of APA Division 28: The past, present, and future of psychopharmacology and substance abuse.

    PubMed

    Stoops, William W; Sigmon, Stacey C; Evans, Suzette M

    2016-08-01

    This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record PMID:27454671

  19. EDITORIAL: 50th anniversary issue

    NASA Astrophysics Data System (ADS)

    Beddoe, Alun H.

    2006-07-01

    In July 1956, 50 years ago, the first issue of Physics in Medicine and Biology (PMB) was published. It was subtitled The Journal of the Hospital Physicists' Association and published in association with the Philosophical Magazine by Taylor and Francis. Subscriptions were £1 per part or £3 10s for an annual subscription. The Editor, Professor J E Roberts, prefaced the first issue with a cautious editorial noting: The appearance of a new journal is usually greeted with mixed feelings by scientific workers, a common response being that there are far too many journals already. Justification for a new publication is only possible if there is a clearly defined gap in the publishing facilities available to workers in a particular scientific field.... Professor Roberts ended by seeking support from the scientific community for the new venture. He certainly got it! From a tentative few hundred pages in four issues a year for the first few years, the journal is now issued twice monthly with nearly 8000 pages expected in volume 51. In this anniversary issue we have invited some 28 senior authors to submit papers on a range of subjects spanning the discipline. We decided that to be an author one had to be old, but age was not to be the only criterion! Indeed readers will recognize all names as major contributors to both the development of medical physics and the success of PMB. Authors were not asked to write formal topical reviews of the state-of-the-art of the sub-disciplines which make up medical physics, but rather to present short historical reviews, didactic in style, perhaps highlighting the role of PMB in the development of their fields. Nevertheless, other than a page limit (which many subsequently ignored!) no formal format was imposed on authors, so what follows is a range of contributions from the almost conversational, personal statement to the more formal and familiar scientific paper. Whatever the writing style we are confident that readers will gain some appreciation of the development of our wide-ranging discipline over the last half century. Some readers may feel that one or two subjects have not been represented, and for that I can only apologise. We did ask for contributions to several other topics (for example radiation metrology and optical techniques) but inevitably there were authors who for various reasons were unable to meet the deadline. Inevitably we will also have missed contributions from excellent potential authors (who satisfied the age criterion!). As Guest Editor I must bear the responsibility for those omissions. While page limits do not permit me to discuss the contributions to this issue individually I would like to mention the first contribution by Dr J E (Bob) Burns. Dr Burns was on the Editorial Board in the early sixties working with the second Editor, Professor Sir Joseph Rotblat. Both in his article and in personal communications Dr Burns has emphasized the important role of Professor Rotblat in the early years. I did write to Professor Rotblat seeking a contribution from him but, sadly, received a reply saying that he was not well enough to contribute `at present'; he died a few weeks later at the age of 96 years (please refer to www.pugwash.org for tributes from Mikhail Gorbachev, Kofi Annan and many others). Dr Burns wrote a short note to me shortly after his death including the following comment which is reproduced below: Although many people have contributed to the success of PMB over the last 50 years it was Rotblat's restless energy, power of persuasion and already existing fame (he was well known both scientifically and to the public at the time) that enabled him to rescue the journal from an early death. After discussions with colleagues around the UK, including Dr Burns, and with the Editorial Board, we all felt that it would be highly appropriate to dedicate this anniversary issue to the memory of Professor Rotblat. Institute of Physics Publishing (IOP) took over the publishing of PMB in 1972, firstly on behalf of the Hospital Physicists' Association and then on behalf of the I

  20. 50th Anniversary: Freedom 7

    NASA Video Gallery

    On May 5, 1961, Alan Shepard was propelled into space aboard the Mercury capsule Freedom 7. His 15-minute suborbital flight was part of Project Mercury, the United States' first man-in-space progra...

  1. Increased Physical Activity and Fitness above the 50(th) Percentile Avoid the Threat of Older Adults Becoming Institutionalized: A Cross-sectional Pilot Study.

    PubMed

    Pereira, Catarina; Fernandes, Jorge; Raimundo, Armando; Biehl-Printes, Clarissa; Marmeleira, José; Tomas-Carus, Pablo

    2016-02-01

    The objective of this study was to analyze the impact of physical fitness and physical activity on the threat of older adults without cognitive impairment becoming institutionalized. This cross-sectional study involved 195 non-institutionalized (80.1 ± 4.4 years) and 186 institutionalized (83.8 ± 5.2years) participants. Cognitive impairment was assessed using Mini-Mental State Examination, measures of physical fitness were determined by the Senior Fitness Test, and physical activity was assessed using the International Physical Activity Questionnaire. Multivariate binary logistic analysis selected four main determinants of institutionalization in both genders: The likelihood of becoming institutionalized increased by +18.6% for each additional year of age, whereas it decreased by -24.8% by each fewer kg/m(2) in body mass index (BMI), by -0.9% for each additional meter performed in the aerobic endurance test, and by -2.0% for each additional 100 metabolic equivalent of task (MET)-min/week of physical activity expenditure (p < 0.05). Values ≤50(th) percentile (age ≥81 years, BMI ≥26.7 kg/m(2), aerobic endurance ≤367.6 meters, and physical activity ≤693 MET-min/week) were computed using receiver operating characteristics analysis as cutoffs discriminating institutionalized from non-institutionalized older adults. The performance of physical activity, allied to an improvement in physical fitness (mainly BMI and aerobic endurance), may avoid the threat of institutionalization of older adults without cognitive impairment only if they are above the 50(th) percentile. The following parameters are highly recommended: Expending ≥693 MET-min/week on physical activity, having a BMI ≤26.7 kg/m(2), and being able to walk ≥367.6 meters in the aerobic endurance test, especially above the age of 80 years. The discovery of this trigger justifies the development of physical activity programs targeting the pointed cutoffs in old and very old adults

  2. A portrait of the C4 photosynthetic family on the 50th anniversary of its discovery: species number, evolutionary lineages, and Hall of Fame.

    PubMed

    Sage, Rowan F

    2016-07-01

    Fifty years ago, the C4 photosynthetic pathway was first characterized. In the subsequent five decades, much has been learned about C4 plants, such that it is now possible to place nearly all C4 species into their respective evolutionary lineages. Sixty-one independent lineages of C4 photosynthesis are identified, with additional, ancillary C4 origins possible in 12 of these principal lineages. The lineages produced ~8100 C4 species (5044 grasses, 1322 sedges, and 1777 eudicots). Using midpoints of stem and crown node dates in their respective phylogenies, the oldest and most speciose C4 lineage is the grass lineage Chloridoideae, estimated to be near 30 million years old. Most C4 lineages are estimated to be younger than 15 million years. Older C4 lineages tend to be more speciose, while those younger than 7 million years have <43 species each. To further highlight C4 photosynthesis for a 50th anniversary snapshot, a Hall of Fame comprised of the 40 most significant C4 species is presented. Over the next 50 years, preservation of the Earth's C4 diversity is a concern, largely because of habitat loss due to elevated CO2 effects, invasive species, and expanded agricultural activities. Ironically, some members of the C4 Hall of Fame are leading threats to the natural C4 flora due to their association with human activities on landscapes where most C4 plants occur. PMID:27053721

  3. The effects of fructose-containing sugars on weight, body composition and cardiometabolic risk factors when consumed at up to the 90th percentile population consumption level for fructose.

    PubMed

    Lowndes, Joshua; Sinnett, Stephanie; Yu, Zhiping; Rippe, James

    2014-08-01

    The American Heart Association (AHA) and World Health Organization (WHO) have recommended restricting calories from added sugars at lower levels than the Institute of Medicine (IOM) recommendations, which are incorporated in the Dietary Guidelines for Americans 2010 (DGAs 2010). Sucrose (SUC) and high fructose corn syrup (HFCS) have been singled out for particular concern, because of their fructose content, which has been specifically implicated for its atherogenic potential and possible role in elevating blood pressure through uric acid-mediated endothelial dysfunction. This study explored the effects when these sugars are consumed at typical population levels up to the 90th percentile population consumption level for fructose. Three hundred fifty five overweight or obese individuals aged 20-60 years old were placed on a eucaloric diet for 10 weeks, which incorporated SUC- or HFCS-sweetened, low-fat milk at 8%, 18% or 30% of calories. There was a slight change in body weight in the entire cohort (169.1 ± 30.6 vs. 171.6 ± 31.8 lbs, p < 0.01), a decrease in HDL (52.9 ± 12.2 vs. 52.0 ± 13.9 mg/dL, p < 0.05) and an increase in triglycerides (104.1 ± 51.8 vs. 114.1 ± 64.7 mg/dL, p < 0.001). However, total cholesterol (183.5 ± 42.8 vs. 184.4 mg/dL, p > 0.05), LDL (110.3 ± 32.0 vs. 110.5 ± 38.9 mg/dL, p > 0.05), SBP (109.4 ± 10.9 vs. 108.3 ± 10.9 mmHg, p > 0.05) and DBP (72.1 ± 8.0 vs. 71.3 ± 8.0 mmHg, p > 0.05) were all unchanged. In no instance did the amount or type of sugar consumed affect the response to the intervention (interaction p > 0.05). These data suggest that: (1) when consumed as part of a normal diet, common fructose-containing sugars do not raise blood pressure, even when consumed at the 90th percentile population consumption level for fructose (five times the upper level recommended by the AHA and three times the upper level recommended by WHO); (2) changes in the lipid profile are mixed, but modest. PMID:25111121

  4. Rural Sociology: The Wisconsin Contribution, Current Status and Future Directions. Proceedings of the 50th Anniversary Symposium of the Department of Rural Sociology, University of Wisconsin (Madison, Wisconsin, May 8-9, 1982).

    ERIC Educational Resources Information Center

    Wisconsin Univ., Madison. Coll. of Agricultural and Life Sciences.

    Papers presented at a symposium commemorating the 50th anniversary of the founding of the Department of Rural Sociology of the University of Wisconsin-Madison are collected in this volume. The first four papers--by Olaf Larson, Edward Moe, Daryl Hobbs, and Robert Gard--discuss the department's history, emphasizing the contributions of outstanding…

  5. An inflatable belt system in the rear seat occupant environment: investigating feasibility and benefit in frontal impact sled tests with a 50th percentile male ATD

    PubMed Central

    Forman, Jason L.; Lopez-Valdes, Francisco J.; Dennis, Nate; Kent, Richard W.; Tanji, Hiromasa; Higuchi, Kazuo

    2010-01-01

    Frontal-impact airbag systems have the potential to provide a benefit to rear seat occupants by distributing restraining forces over the body in a manner not possible using belts alone. This study sought to investigate the effects of incorporating a belt-integrated airbag (“airbelt”) into a rear seat occupant restraint system. Frontal impact sled tests were performed with a Hybrid III 50th percentile male anthropomorphic test device (ATD) seated in the right-rear passenger position of a 2004 mid-sized sedan buck. Tests were performed at 48 km/h (20 g, 100 ms acceleration pulse) and 29 km/h (11 g, 100 ms). The restraints consisted of a 3-point belt system with a cylindrical airbag integrated into the upper portion of the shoulder belt. The airbag was tapered in shape, with a maximum diameter of 16 cm (at the shoulder) that decreased to 4 cm at the mid-chest. A 2.5 kN force-limiter was integrated into the shoulder-belt retractor, and a 2.3 kN pretensioner was present in the out-board anchor of the lap belt. Six ATD tests (three 48 km/h and three 29 km/h) were performed with the airbelt system. These were compared to previous frontal-impact, rear seat ATD tests with a standard (not-force-limited, not-pretensioned) 3-point belt system and a progressive force-limiting (peak 4.4 kN), pretensioning (FL+PT) 3-point belt system. In the 48 km/h tests, the airbelt resulted in significantly less (p<0.05, two-tailed Student’s t-test) posterior displacement of the sternum towards the spine (chest deflection) than both the standard and FL+PT belt systems (airbelt: average 13±1.1 mm standard deviation; standard belt: 33±2.3 mm; FL+PT belt: 23±2.6 mm). This was consistent with a significant reduction in the peak upper shoulder belt force (airbelt: 2.7±0.1 kN; standard belt: 8.7±0.3 kN; FL+PT belt: 4.4±0.1 kN), and was accompanied by a small increase in forward motion of the head (airbelt: 54±0.4 cm; standard belt: 45±1.3 cm; FL+PT belt: 47±1.1 cm) The airbelt system

  6. [Changes in heart rate variability after myocardial infarction. Value of Poincareé's diagram].

    PubMed

    Copie, X; Le Heuzey, J Y; Iliou, M C; Pousset, F; Lavergne, T; Guize, L

    1995-11-01

    The variability of the heart rate is reduced after myocardial infarction. It then progressively increases, to return to near normal values after several months. However, these changes in heart rate variability occur at the same time as slowing of the heart rate which makes interpretation difficult. Poincaré's diagram is constructed from a Holter recording plotting each RR interval against the preceding RR interval. The authors have developed a geometric approach to this diagram to evaluate parasympathetic tone for a given heart rate. By measuring the dispersion in height of the Poincaré's diagram, the authors evaluate the shor-term variability for a given RR interval. Two 24 hr Holter recordings were performed in 52 patients at one and two weeks after a myocardial infarction. The dispersion in the height of the Poincaré's diagrams was measured at the 10th, 25th, 50th, 75th and 90th percentiles of the total dispersion. The authors have shown an increase in the short-term variability of the shortest RR intervals (1th, 25th and 50th percentiles) which is not observed in the longer RR intervals (75th and 90th percentiles). In conclusion, theres is an increase in the heart rate variability at the shortest RR intervals. This suggests that the recovery of parasympathic tone after myocardial infarction occurs mainly at the fastest heart rates. PMID:8745997

  7. Does ability to walk reflect general functionality in inflammatory neuropathies?

    PubMed

    Draak, Thomas H P; Gorson, Kenneth C; Vanhoutte, Els K; van Nes, Sonja I; van Doorn, Pieter A; Cornblath, David R; van den Berg, Leonard H; Faber, Catharina G; Merkies, Ingemar S J

    2016-06-01

    The "ability to walk" is considered a benchmark for good clinical recovery and prognosis, particularly in patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). However, it has never been determined whether being "able to walk" represents general functionality. The purpose of this study was to examine whether the ability to walk outside independently reflects general functional improvement in patients with GBS, CIDP, and gammopathy-related neuropathy (MGUSP). A total of 137 patients with newly diagnosed (or relapsing) GBS (55), CIDP (59), and MGUSP (23) were serially examined (1-year). Predefined arbitrary cut-offs (so-called patients' Functional-Acceptable-Clinical-Thresholds [FACTs]) were taken at the 50th, 75th, and 90th percentile of the Inflammatory-Rasch-built-Overall-Disability-Scale (I-RODS(©) ). We determined the proportion of patients able to walk outside independently that reached the postulated cut-offs. A mean total of 85%, 39%, and 12% of all patients able to walk reached 50th, 75th, and 90th percentile thresholds, respectively. These findings were not neuropathy type related. Our findings show that assessing only one construct of functionality (e.g., walking ability) does not reflect the full scope of daily/social functional deficits perceived by patients. The ability to walk shows a patient is doing better, but not necessarily doing well. The I-RODS(©) bypasses these limitations. PMID:26968437

  8. The effect of anatomical modeling on space radiation dose estimates: a comparison of doses for NASA phantoms and the 5th, 50th, and 95th percentile male and female astronauts

    NASA Astrophysics Data System (ADS)

    Bahadori, Amir A.; Van Baalen, Mary; Shavers, Mark R.; Dodge, Charles; Semones, Edward J.; Bolch, Wesley E.

    2011-03-01

    The National Aeronautics and Space Administration (NASA) performs organ dosimetry and risk assessment for astronauts using model-normalized measurements of the radiation fields encountered in space. To determine the radiation fields in an organ or tissue of interest, particle transport calculations are performed using self-shielding distributions generated with the computer program CAMERA to represent the human body. CAMERA mathematically traces linear rays (or path lengths) through the computerized anatomical man (CAM) phantom, a computational stylized model developed in the early 1970s with organ and body profiles modeled using solid shapes and scaled to represent the body morphometry of the 1950 50th percentile (PCTL) Air Force male. With the increasing use of voxel phantoms in medical and health physics, a conversion from a mathematical-based to a voxel-based ray-tracing algorithm is warranted. In this study, the voxel-based ray tracer (VoBRaT) is introduced to ray trace voxel phantoms using a modified version of the algorithm first proposed by Siddon (1985 Med. Phys. 12 252-5). After validation, VoBRAT is used to evaluate variations in body self-shielding distributions for NASA phantoms and six University of Florida (UF) hybrid phantoms, scaled to represent the 5th, 50th, and 95th PCTL male and female astronaut body morphometries, which have changed considerably since the inception of CAM. These body self-shielding distributions are used to generate organ dose equivalents and effective doses for five commonly evaluated space radiation environments. It is found that dosimetric differences among the phantoms are greatest for soft radiation spectra and light vehicular shielding.

  9. 50th anniversary of the laser

    NASA Astrophysics Data System (ADS)

    Bertolotti, M.

    2010-09-01

    On July, 7, 1960 a press conference at Huyghes announced that Maiman had assembled and put into operation the first laser. It was the very pulsed ruby laser that everybody knows today. The announcement came as a bomb. Nobody expected that in an unknown laboratory, new to the race to build a laser, this result could be obtained. It was such an unexpected result that many still today mantain that the true laser was discovered at Bell by Shawlow. This result was achieved through a long story which passed by the Townes maser and many tentative experiments and discussions both in the USA and Soviet Union. In this special issue we present a collection of papers which provide further information as to what happened after Einstein introduced the concept of stimulated emission. The first paper is a short paper by Townes on the development of the physics of microwaves following the creation of the maser. When the laser came on the stage one of its properties was the inherent coherence of the emitted light. Emil Wolf's contribution enlights the early days of coherence to which he so much contributed and the very timely first Rochester Conference which was held on June 27-29, 1960 a few days before the Times announcement of the Maiman achievement. Important contributions were given by Soviet Scientists and, Svetlana Lukishova's contributions helps us understand the work of Valentin Fabrikant which was mostly unknown to western scientists. At the end of his life, Maiman went to Vancouver in Canada and Andrew H. Rawicz gives his testimoniancy of his friendship there. Coherence and the statistical properties of laser light were much studied and we have two exceptional papers by Roy Pike and Jan Perina discussing these arguments. The issue also contains three more papers presenting some earlier achievements in the construction of multiquantumwell laser (M. L. Dotor, P. Huertas, P. A. Postigo, D. Golmayo and F. Briones), the first measurements on very short pulses (H. P. Weber and R. Dandliker) and spatial coherence (D. P. Barato and M. L. Calvo).

  10. 50th anniversary of the word "allosteric".

    PubMed

    Changeux, Jean-Pierre

    2011-07-01

    A brief historical account on the origin and meaning of the word "allosteric" is presented. The word was coined in an attempt to qualify the chemical mechanism of the feedback inhibition of bacterial enzymes by regulatory ligands. The data lead to the proposal that, at variance with the classical mechanism of mutual exclusion by steric hindrance, the inhibition takes place through an "allosteric" interaction between "no overlapping", stereospecifically distinct, sites for substrate and feedback inhibitor, mediated by a discrete reversible alteration of the molecular structure of the protein. PMID:21574197

  11. Genomics in personalized cancer medicine and its impact on early drug development in China: report from the 6th Annual Meeting of the US Chinese Anti-Cancer Association (USCACA) at the 50th ASCO Annual Meeting.

    PubMed

    Zhang, Wei; Cheng, Shi-Yuan; Hou, Li-Fang; Yan, Li; Tong, Yun-Guang

    2014-08-01

    The 6th Annual Meeting of the United States Chinese Anti-Cancer Association (USCACA) was held in conjunction with the 50th Annual Meeting of American Society of Clinical Oncology (ASCO) on May 30, 2014 in Chicago, Illinois, the United States of America. With a focus on personalized medicine, the conference featured novel approaches to investigate genomic aberrations in cancer cells and innovative clinical trial designs to expedite cancer drug development in biomarker-defined patient populations. A panel discussion further provided in-depth advice on advancing development of personalized cancer medicines in China. The conference also summarized USCACA key initiatives and accomplishments, including two awards designated to recognize young investigators from China for their achievements and to support their training in the United States. As an effort to promote international collaboration, USCACA will team up with Chinese Society of Clinical Oncology (CSCO) to host a joint session on "Breakthrough Cancer Medicines" at the upcoming CSCO Annual Meeting on September 20th, 2014 in Xiamen, China. PMID:25096543

  12. The 2014 Surgeon General's report: commemorating the 50th Anniversary of the 1964 Report of the Advisory Committee to the US Surgeon General and updating the evidence on the health consequences of cigarette smoking.

    PubMed

    Alberg, Anthony J; Shopland, Donald R; Cummings, K Michael

    2014-02-15

    The question of whether cigarette smoking was associated with lung cancer was central to the expansion of epidemiology into the study of chronic diseases in the 1950s. The culmination of this era was the 1964 report of the Advisory Committee to the Surgeon General, a landmark document that included an objective synthesis of the evidence of the health consequences of smoking according to causal criteria. The report concluded that cigarette smoking was a cause of lung cancer in men and sufficient in scope that "remedial action" was warranted at the societal level. The 2014 Surgeon General's report commemorates the 50th anniversary of the 1964 report. The evidence on the health consequences of smoking has been updated many times in Surgeon General's reports since 1964. These have summarized our increasingly greater understanding of the broad spectrum of the deleterious health effects of exposure to tobacco smoke across most major organ systems. In turn, this evidence has been translated into tobacco control strategies implemented to protect the public's health. The Surgeon General report process is an enduring example of evidence-based public health in practice. Substantial progress has been made, but cigarette smoking remains one of the most pressing global health issues of our time. PMID:24436362

  13. Abdominal Organ Location, Morphology, and Rib Coverage for the 5th, 50th, and 95th Percentile Males and Females in the Supine and Seated Posture using Multi-Modality Imaging

    PubMed Central

    Hayes, Ashley R.; Gayzik, F. Scott; Moreno, Daniel P.; Martin, R. Shayn; Stitzel, Joel D.

    2013-01-01

    The purpose of this study was to use data from a multi-modality image set of males and females representing the 5th, 50th, and 95th percentile (n=6) to examine abdominal organ location, morphology, and rib coverage variations between supine and seated postures. Medical images were acquired from volunteers in three image modalities including Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and upright MRI (uMRI). A manual and semi-automated segmentation method was used to acquire data and a registration technique was employed to conduct a comparative analysis between abdominal organs (liver, spleen, and kidneys) in both postures. Location of abdominal organs, defined by center of gravity movement, varied between postures and was found to be significant (p=0.002 to p=0.04) in multiple directions for each organ. In addition, morphology changes, including compression and expansion, were seen in each organ as a result of postural changes. Rib coverage, defined as the projected area of the ribs onto the abdominal organs, was measured in frontal, lateral, and posterior projections, and also varied between postures. A significant change in rib coverage between postures was measured for the spleen and right kidney (p=0.03 and p=0.02). The results indicate that posture affects the location, morphology and rib coverage area of abdominal organs and these implications should be noted in computational modeling efforts focused on a seated posture. PMID:24406951

  14. Temporal and spatial trends of chloride and sodium in groundwater in New Hampshire, 1960–2011

    USGS Publications Warehouse

    Medalie, Laura

    2012-01-01

    Data on concentrations of chloride and sodium in groundwater in New Hampshire were assembled from various State and Federal agencies and organized into a database. This report provides documentation of many assumptions and limitations of disparate data that were collected to meet wide-ranging objectives and investigates temporal and spatial trends of the data. Data summaries presented in this report and analyses performed for this study needed to take into account the 27 percent of chloride and 5 percent of sodium data that were censored (less than a reporting limit) at multiple reporting limits that systematically decreased over time. Throughout New Hampshire, median concentrations of chloride were significantly greater during 2000-2011 than in every decade since the 1970s, and median concentrations of sodium were significantly greater during 2000-2011 than during the 1990s. Results of summary statistics showed that the 50th, 75th, and 90th percentiles of the median concentrations of chloride and sodium by source (well) from Rockingham and Strafford counties were the highest in the State; and the 75th and 90th percentiles from Carroll, Coos, and Grafton counties were the lowest. Large increases in median concentrations of chloride and sodium for individual wells after 1995 compared with concentrations for years before were found in parts of Belknap and Rockingham counties and in small clusters within Carroll, Hillsborough, and Merrimack counties.

  15. Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday

    NASA Astrophysics Data System (ADS)

    Dowker, Fay; Elizalde, Emilio; Kirsten, Klaus

    2012-09-01

    extension that impacts particles never entering that region. What is the gravitational analogue for that situation? The analogue concerns the impact a localized curvature has, and the cone is an excellent example to shed light on that question. Related to the method of images, Stuart has done an enormous amount of work on the influence of topology and curvature on quantum field theory. An example is [17], where the vacuum stress-energy tensor for Clifford-Klein forms of the flat or spherical type were computed. Another strand we would like to mention is Stuart's interest in higher spin equations. In [18], Steven Weinberg wrote down a set of higher spin equations that took his fancy. They involved angular momentum theory, which has always pleased Stuart, and the description was an alternative to Roger Penrose's use of two-spinors. Investigating the inconsistencies that arose on coupling to gauge theories, Stuart extended the classic results in [19], from electromagnetism to gravity in accordance with his general philosophy; see, e.g., [20, 21, 22]. Lately, Stuart is best known for his many applications in the context of zeta function regularization and its applications to quantum field theory under external conditions and spectral theory. He can be considered the world expert on particular case calculations with a knowledge of the literature, old and recent, that is not seen very often and which originated in the many hours spent at different (mostly British) libraries. His attitude towards explicit computations is nicely summarized by himself: 'I have always been interested in exact solutions, even if unphysical, so long as they are pretty. They seem to be working mechanisms that fit together, complete in themselves, like a watch.' The following issue in honour of Stuart's 75th birthday contains contributions that touch upon the various topics he has worked on. References [1] de Broglie L 1928 La mécanique ondulatoire (Paris: Gauthier-Villars) [2] Castillejo L, Dalitz R H

  16. CONFERENCES AND SYMPOSIA: On the 50th anniversary of the L F Vereshchagin Institute for High Pressure Physics, RAS (Scientific outreach session of the Physical Sciences Division of the Russian Academy of Sciences, 23 April 2008)

    NASA Astrophysics Data System (ADS)

    Stishov, S. M.; Khvostantsev, L. G.; Slesarev, V. N.; Popova, S. V.; Brazhkin, V. V.; Dyuzheva, T. I.; Dzhavadov, L. N.; Gromnitskaya, E. L.; Stepanov, G. N.; Timofeev, Yu A.; Dizhur, E. M.; Venttsel, V. A.; Voronovskii, A. N.; Ryzhov, V. N.; Barabanov, A. F.; Magnitskaya, M. V.; Tareeva, E. E.

    2008-10-01

    A scientific outreach session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) was held on 23 April 2008 at the Institute for High Pressure Physics, RAS, Troitsk, Moscow region. The session was devoted to the 50th anniversary of the Institute. The following reports were presented: (1) Stishov S M (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "The Institute for High Pressure Physics is now 50 (opening address)"; (2) Khvostantsev L G and Slesarev V N (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Large-volume high-pressure devices for physical investigations"; (3) Popova S V, Brazhkin V V and Dyuzheva T I (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Structural phase transitions in highly compressed substances and the synthesis of high-pressure phases"; (4) Dzhavadov L N, Gromnitskaya E L, Stepanov G N and Timofeev Yu A (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Studies of the thermodynamic, elastic, superconducting, and magnetic properties of substances at high pressures"; (5) Dizhur E M, Venttsel V A and Voronovskii A N (Institute for High Pressure Physics, RAS, Troitsk, Moscow region), "Quantum transport at high pressures"; (6) Ryzhov V N, Barabanov A F, Magnitskaya M V and Tareyeva E E (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Theoretical studies of condensed matter"; (7) Bugakov V I, Antanovich A A, Konyaev Yu S and Slesarev V N (Institute for High Pressure Physics, RAS, Troitsk, Moscow region) "Designing new construction and superhard materials and related tools." An abridged version of reports 1 -6 is presented below. • The Institute for High Pressure Physics is now 50 (opening address), Stishov S M Physics-Uspekhi, 2008, Volume 51, Number 10, Pages 1055-1059 • Large-volume high-pressure devices for physical investigations, Khvostantsev L G and Slesarev V N Physics-Uspekhi, 2008, Volume 51, Number 10, Pages 1059

  17. 75th anniversary of the N V Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN) (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 25 February 2015)

    NASA Astrophysics Data System (ADS)

    2015-06-01

    A scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) celebrating the 75th anniversary of the N V Pushkov Institute of Terrestrial Magnetism, Ionosphere, and Radio Wave Propagation of the RAS (IZMIRAN) was held in the IZMIRAN conference hall on 25 February 2015. The agenda of the session announced on the website http://www.gpad.ac.ru of the RAS Physical Sciences Division contained the following reports: (1) Kuznetsov V D (IZMIRAN, Moscow) "N V Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN) yesterday, today, and tomorrow"; (2) Gvishiani A D (Geophysical Center, Moscow) "Studies of the terrestrial magnetic field and the network of Russian magnetic laboratories"; (3) Sokoloff D D (Faculty of Physics, Lomonosov Moscow State University, Moscow) "Magnetic dynamo questions"; (4) Petrukovich A A (Space Research Institute, RAS, Moscow) "Some aspects of magnetosphere-ionosphere relations"; (5) Lukin D S (Moscow Institute of Physics and Technology (State University), Dolgoprudnyi, Moscow region) "Current problems of ionospheric radio wave propagation"; (6) Safargaleev V V (Polar Geophysical Institute, Kola Scientific Center, RAS, Murmansk), Sergienko T I (Swedish Institute of Space Physics (IRF), Sweden), Kozlovskii A E (Sodankyl \\ddot a Geophysical Observatory, Finland), Safargaleev A V (St. Petersburg State University, St. Petersburg), Kotikov A L (St. Petersburg Branch of IZMIRAN, St. Petersburg) "Magnetic and optical measurements and signatures of reconnection in the cusp and vicinity"; (7) Kuznetsov V D (IZMIRAN, Moscow) "Space solar research: achievements and prospects". Papers written on the basis of oral reports 1, 3, 4, 6, and 7 are given below. • N V Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN) yesterday, today, tomorrow, V D Kuznetsov Physics-Uspekhi, 2015

  18. PREFACE: SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor: Devoted to the 75th anniversary of Yu M Ostanevich's birth

    NASA Astrophysics Data System (ADS)

    Gordely, Valentin; Kuklin, Alexander; Balasoiu, Maria

    2012-03-01

    The Second International Workshop 'SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor', devoted to the 75th anniversary of the birth of Professor Yu M Ostanevich (1936-1992), an outstanding neutron physicist and the founder of small-angle neutron scattering (field, group, and instrument) at JINR FLNPh, was held on 27-30 May at the Frank Laboratory of Neutron Physics. The first Workshop was held in October 2006. Research groups from different neutron centers, universities and research institutes across Europe presented more than 35 oral and poster presentations describing scientific and methodological results. Most of them were obtained with the help of the YuMO instrument before the IBR-2 shutdown in 2006. For the last four years the IBR-2 reactor has been shut down for refurbishment. At the end of 2010 the physical launch of the IBR-2M reactor was finally realized. Nowadays the small-angle neutron scattering (SANS) technique is applied to a wide range of scientific problems in condensed matter, soft condensed matter, biology and nanotechnology, and despite the fact that there are currently over 30 SANS instruments in operation worldwide at both reactor and spallation sources, the demand for beam-time is considerably higher than the time available. It must be remembered, however, that as the first SANS machine on a steady-state reactor was constructed at the Institute Laue Langevin, Grenoble, the first SANS instrument on a 'white' neutron pulsed beam was accomplished at the Joint Institute for Nuclear Research at the IBR-30 reactor, beamline N5. During the meeting Yu M Ostanevich's determinative and crucial contribution to the construction of spectrometers at the IBR-2 high-pulsed reactor was presented, as well as his contribution to the development of the time-of-flight (TOF) small-angle scattering technique, and a selection of other scientific areas. His leadership and outstanding scientific achievements in applications of the

  19. Relationships between atmospheric circulation indices and rainfall in Northern Algeria and comparison of observed and RCM-generated rainfall

    NASA Astrophysics Data System (ADS)

    Taibi, S.; Meddi, M.; Mahé, G.; Assani, A.

    2015-09-01

    This work aims, as a first step, to analyze rainfall variability in Northern Algeria, in particular extreme events, during the period from 1940 to 2010. Analysis of annual rainfall shows that stations in the northwest record a significant decrease in rainfall since the 1970s. Frequencies of rainy days for each percentile (5th, 10th, 25th, 50th, 75th, 90th, 95th, and 99th) and each rainfall interval class (1-5, 5-10, 10-20, 20-50, and ≥50 mm) do not show a significant change in the evolution of daily rainfall. The Tenes station is the only one to show a significant decrease in the frequency of rainy days up to the 75th percentile and for the 10-20-mm interval class. There is no significant change in the temporal evolution of extreme events in the 90th, 95th, and 99th percentiles. The relationships between rainfall variability and general atmospheric circulation indices for interannual and extreme event variability are moderately influenced by the El Niño-Southern Oscillation and Mediterranean Oscillation. Significant correlations are observed between the Southern Oscillation Index and annual rainfall in the northwestern part of the study area, which is likely linked with the decrease in rainfall in this region. Seasonal rainfall in Northern Algeria is affected by the Mediterranean Oscillation and North Atlantic Oscillation in the west. The ENSEMBLES regional climate models (RCMs) are assessed using the bias method to test their ability to reproduce rainfall variability at different time scales. The Centre National de Recherches Météorologiques (CNRM), Czech Hydrometeorological Institute (CHMI), Eidgenössische Technische Hochschule Zürich (ETHZ), and Forschungszentrum Geesthacht (GKSS) models yield the least biased results.

  20. UConn Hosts IACLEA for 50th Annual Conference

    ERIC Educational Resources Information Center

    Hudd, Robert S.

    2008-01-01

    The decision that led to the 1992 opening of the University of Connecticut's new public safety complex was excellent timing. Three years after the complex opened, complete with a state-of-the-art Public Safety Answering Point (PSAP), an emergency operations/training center and an indoor firing range, the quiet, nearly 4,000-acre UConn campus…

  1. 'Focus on Marshall' Marks Milestone With 50th Episode

    NASA Video Gallery

    Hard to believe, but it's been five years since the Marshall Space Flight Center began a video program called "Focus on Marshall." In those five years, co-hosts Bill Hubscher and Lori Meggs, have t...

  2. Fracture faces of frozen membranes: 50th anniversary

    PubMed Central

    Branton, Daniel

    2016-01-01

    In 1961, the development of an improved freeze-etching (FE) procedure to prepare rapidly frozen biological cells or tissues for electron microscopy raised two important questions. How does a frozen cell membrane fracture? What do the extensive face views of the cell’s membranes exposed by the fracture process of FE tell us about the overall structure of biological membranes? I discovered that all frozen membranes tend to split along weakly bonded lipid bilayers. Consequently, the fracture process exposes internal membrane faces rather than either of the membrane’s two external surfaces. During etching, when ice is allowed to sublime after fracturing, limited regions of the actual membrane surfaces are revealed. Examination of the fractured faces and etched surfaces provided strong evidence that biological membranes are organized as lipid bilayers with some proteins on the surface and other proteins extending through the bilayer. Membrane splitting made it possible for electron microscopy to show the relative proportion of a membrane’s area that exists in either of these two organizational modes. PMID:26823391

  3. The Classic Guide to Better Writing. 50th Anniversary Edition.

    ERIC Educational Resources Information Center

    Flesch, Rudolf; Lass, A. H.

    This handbook, first published 50 years ago, is designed to teach individuals how to write more effectively. It offers step-by-step techniques and exercises to write simply, clearly, and correctly. New features in this edition of the handbook include contemporary examples, and guidelines for computer assisted research and writing and for…

  4. Fracture faces of frozen membranes: 50th anniversary.

    PubMed

    Branton, Daniel

    2016-02-01

    In 1961, the development of an improved freeze-etching (FE) procedure to prepare rapidly frozen biological cells or tissues for electron microscopy raised two important questions. How does a frozen cell membrane fracture? What do the extensive face views of the cell's membranes exposed by the fracture process of FE tell us about the overall structure of biological membranes? I discovered that all frozen membranes tend to split along weakly bonded lipid bilayers. Consequently, the fracture process exposes internal membrane faces rather than either of the membrane's two external surfaces. During etching, when ice is allowed to sublime after fracturing, limited regions of the actual membrane surfaces are revealed. Examination of the fractured faces and etched surfaces provided strong evidence that biological membranes are organized as lipid bilayers with some proteins on the surface and other proteins extending through the bilayer. Membrane splitting made it possible for electron microscopy to show the relative proportion of a membrane's area that exists in either of these two organizational modes. PMID:26823391

  5. 50th International Winter Meeting on Nuclear Physics

    NASA Astrophysics Data System (ADS)

    Unlike many workshops, the Bormio meeting does not focus on a single topic. Instead, the aim is to bring together researchers and students from related fields in subatomic physics. Addressed topics include hadron physics, heavy ion physics, nuclear astrophysics and nuclear structure, particle physics, detectors and future projects as well as applications of these fields. Review talks by more senior speakers as well as talks and posters presented by junior researchers are encouraged.

  6. History of aldosterone on its 50th birthday.

    PubMed

    Fiore, Cristina; Calò, Lorenzo A; Colombo, Lorenzo; Grimm, Clarence E; Armanini, Decio

    2006-01-01

    The paper describes the impact of mineralocorticoid substances on water regulation from Theophrastus (IV century B.C.) to Thomas Addison (1849). It also opens to the missed discovery of aldosterone of I.A. Macchi. PMID:16874725

  7. A 50th anniversary guidebook for the desert project

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Desert Project encompasses a 400 square mile areas studied by a team of soil scientists and geologists from 1957 to 1972. The project was staffed by personnel of the Soil Survey Investigations, U.S. Soil Conservation Service, and work was done in cooperation with the Agricultural Experiment Stat...

  8. Magnus Strandqvist: 50th anniversary of his doctoral thesis.

    PubMed

    Kajanti, M J

    1994-01-01

    This article is dedicated to Magnus Strandqvist's famous doctoral thesis "Studien über die kumulative Wirkung der Röntgenstrahlen bei Fraktionierung. Erfahrungen aus dem Radiumhemmet an 280 Haut- und Lippenkarzinomen" published in Acta Radiologica in 1944. After a short biography of Strandqvist some central points of his work and their influence on future development of modern radiotherapy are presented. PMID:7993639

  9. 76 FR 11933 - 50th Anniversary of the Peace Corps

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    .... (Presidential Sig.) [FR Doc. 2011-5031 Filed 3-2-11; 11:15 am] Billing code 3195-W1-P ... rededicate ourselves to fulfilling the dream and continuing the work of all those who aspire and yearn...

  10. Psychomotor development in Argentinean children aged 0-5 years.

    PubMed

    Lejarraga, Horacio; Pascucci, María Cecilia; Krupitzky, Sara; Kelmansky, Diana; Bianco, Ana; Martínez, Elena; Tibaldi, Fabián; Cameron, Noel

    2002-01-01

    In Argentina, there is no information on ages of attainment of developmental milestones and very few data about environmental factors that influence them. A national survey on the psychomotor development of children under 6 years of age was carried out with the help of 129 paediatricians. Logistic regression was applied to a final sample of 3573 healthy, normal children in order to estimate selected centiles (25th, 50th, 75th and 90th), together with their respective confidence intervals, of the ages of attainment of 78 developmental items belonging to the following areas: personal-social (18 items), fine motor (19), language (18) and gross motor (23). The 50th centile obtained for each of the 43 comparable items was compared with those obtained in previously standardised tests: DDST, Denver II, Bayley and Chilean scales. Neither significant nor systematic differences were found between our results and those described in the tests used for comparison. Multiple logistic regressions showed that social class, maternal education and sex (female) were associated with earlier attainment of some selected developmental items, achieved at ages later than 1 year. Selected items achieved before the first year of life were not affected by any of the independent environmental variables studied. The information is useful in helping paediatricians in their daily practice for surveillance of development, as baseline information for epidemiological studies on development in our country and for cross-cultural analysis. PMID:11856454

  11. [Navy medical academy (to the 75th anniversary of establishment)].

    PubMed

    Chernikov, O G; Zaimagov, S V

    2016-02-01

    The article is devoted to the history of the creation in 1940 of the Naval Medical Academy on the basis of the 3rd Leningrad Medical Institute and the Institute for sanitary-chemical protection of the People's Commissariat of the USSR. The structure of this institution included, faculties management staff of the medical service, medical and sanitation, Higher Naval Medical School, the Marine Research Institute Medical, higher courses for officers of the medical service, clinical naval hospital. During the period of its activity (1940-1956), the staff of the Naval Medical Academy made a great contribution to the naval medicine and practical public health. The merit of the Academy is not only a beautifully staged academic, medical, research process, but also in the creation of the spirit of the high sea camaraderie, accomplishment and pride for the work which its graduates have dedicated their lives. PMID:27263215

  12. Biomechanics, Exercise Physiology, and the 75th Anniversary of RQES

    ERIC Educational Resources Information Center

    Hamill, Joseph; Haymes, Emily M.

    2005-01-01

    The purpose of this paper is to review the biomechanics and exercise physiology studies published in the Research Quarterly for Exercise and Sport (RQES) over the past 75 years. Studies in biomechanics, a relatively new subdiscipline that evolved from kinesiology, first appeared in the journal about 40 years ago. Exercise physiology studies have…

  13. The bright thread: the Bulletin's 75th anniversary.

    PubMed Central

    Beatty, W K

    1998-01-01

    This chronological review of the Bulletin of the Medical Library Association deals with the years 1911 through 1985. The Bulletin has had nineteen editors, from Marcia C. Noyes and John Ruhräh, M.D. (1911-26), through Susan Crawford, Ph.D. (1983-1986). This paper describes the Bulletin's gradual expansion in size and contents, the initiation of various departments and sections, and some of the pioneering articles. Major steps in expenses, income, and subscription price are given. Important changes in the format and the growth of the administrative and advisory structures are covered. Images PMID:9578946

  14. Reliable radiogenic heat production of representative lithological groups

    NASA Astrophysics Data System (ADS)

    Vilà, Miquel; Fernández, Manel

    2010-05-01

    Determining the temperature distribution within the lithosphere requires the knowledge of the radiogenic heat production (RHP) distribution within the crust and the lithospheric mantle. RHP of crustal rocks varies considerably at different scales as a result of the petrogenetic processes responsible for their formation and therefore RHP depends on the considered lithologies. In this work we address RHP variability of some common lithological groups from a compilation of a total of 2188 representative U, Th and K concentrations of different worldwide rock types derived from 102 geochemical and geophysical datasets previously published. To optimize the use of the generated RHP database we have classified and renamed the rock-type denominations of the original works following a petrologic classification scheme with a hierarchical structure. To compute RHP a reasonable average density was assigned for each lithologic group. The RHP data of each lithological group is presented in cumulative distribution plots, and we report a table with the mean, the standard deviation, the minimum and maximum values, and the significant percentiles (10th, 25th, 50th, 75th and 90th) of these lithological groups. In general, for each lithological group exists a wide zone around the median value with a constant slope indicating RHP values with the same probability of occurrence. This zone usually includes the RHP range defined by the 25th and the 75th percentile. When compare previuos RHP estimates of representative lithological groups with our results it is observed that most of them fall between the 25th and 75th percentiles obtained. We integrate our results in a schematic model of the differentiation processes undergone by lithospheric rocks. This model allows us to discuss the RHP variability for the different igneous, sedimentary and metamorphic lithological groups from a petrogenetic viewpoint. Finally we give some useful guidelines to assign RHP values to lithospheric thermal

  15. A resolution congratulating the American Motorcyclist Association on its 90th Anniversary.

    THOMAS, 113th Congress

    Sen. Manchin, Joe, III [D-WV

    2014-07-10

    07/10/2014 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S4417) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  16. EXPOSURE TO PESTICIDES BY MEDIUM AND ROUTE: THE 90TH PERCENTILE AND RELATED UNCERTAINTIES

    EPA Science Inventory

    This study investigates distributions of exposure to chlorpyrifos and diazinon using the database generated in the state of Arizona by the National Human Exposure Assessment Survey (NHEXAS-AZ). Exposure to pesticide and associated uncertainties are estimated using probabilistic...

  17. 75 FR 34303 - 90th Anniversary of the Department of Labor Women's Bureau, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... our daughters have an equal right and opportunity to pursue the American Dream. NOW, THEREFORE, I... hundred and thirty-fourth. (Presidential Sig.) [FR Doc. 2010-14724 Filed 6-15-10; 11:15 am] Billing code..., 2010 By the President of the United States of America A Proclamation Throughout our history,...

  18. Differential association of cardiorespiratory fitness and central adiposity among US adolescents and adults: A quantile regression approach.

    PubMed

    McDonald, Samantha M; Ortaglia, Andrew; Bottai, Matteo; Supino, Christina

    2016-07-01

    Previous studies assessing the association between cardiorespiratory fitness (CRF) and waist circumference (WC) have often restricted their evaluation to the association of CRF on average WC. Consequently, the assessment of important variations in the relationship of CRF across the WC distribution was precluded. The purpose of this study was to comprehensively evaluate the association between CRF and the distribution of WC using quantile regression. Secondary data analysis was conducted using data from the 1999-2004 NHANES. Participants (n=8260) aged 12-49years with complete data on estimated maximal oxygen consumption and WC were included. Quantile regression models were performed to assess the association between CRF and the 10th, 25th, 50th, 75th and 90th WC percentiles and were adjusted for age and race/ethnicity. For male and female adolescents with high CRF compared to low-fit counterparts, significant negative estimates (2.8 to 20.2cm and 2.3 to 11.2cm, respectively) were observed across most WC percentiles. Similarly, among male and female adults, high CRF was associated with significant reductions in WC across all percentiles (9.5 to 12.0cm and 3.7 to 9.2cm, respectively). For both populations, an increasing trend in the magnitude of the association of high CRF across the WC percentiles was observed. CRF appears to have a differential relationship across the WC distribution with the largest reductions in WC were found among high-fit individuals with the greatest amount of central adiposity (WC≥90th percentile). Additionally, this differential association highlights the significant limitations of statistical techniques used in previous analyses which focused on the center of the distribution. PMID:27002254

  19. A method to assess the influence of individual player performance distribution on match outcome in team sports.

    PubMed

    Robertson, Sam; Gupta, Ritu; McIntosh, Sam

    2016-10-01

    This study developed a method to determine whether the distribution of individual player performances can be modelled to explain match outcome in team sports, using Australian Rules football as an example. Player-recorded values (converted to a percentage of team total) in 11 commonly reported performance indicators were obtained for all regular season matches played during the 2014 Australian Football League season, with team totals also recorded. Multiple features relating to heuristically determined percentiles for each performance indicator were then extracted for each team and match, along with the outcome (win/loss). A generalised estimating equation model comprising eight key features was developed, explaining match outcome at a median accuracy of 63.9% under 10-fold cross-validation. Lower 75th, 90th and 95th percentile values for team goals and higher 25th and 50th percentile values for disposals were linked with winning. Lower 95th and higher 25th percentile values for Inside 50s and Marks, respectively, were also important contributors. These results provide evidence supporting team strategies which aim to obtain an even spread of goal scorers in Australian Rules football. The method developed in this investigation could be used to quantify the importance of individual contributions to overall team performance in team sports. PMID:26853070

  20. Regression equations to estimate seasonal flow duration, n-day high-flow frequency, and n-day low-flow frequency at sites in North Dakota using data through water year 2009

    USGS Publications Warehouse

    Williams-Sether, Tara; Gross, Tara A.

    2016-01-01

    Seasonal mean daily flow data from 119 U.S. Geological Survey streamflow-gaging stations in North Dakota; the surrounding states of Montana, Minnesota, and South Dakota; and the Canadian provinces of Manitoba and Saskatchewan with 10 or more years of unregulated flow record were used to develop regression equations for flow duration, n-day high flow and n-day low flow using ordinary least-squares and Tobit regression techniques. Regression equations were developed for seasonal flow durations at the 10th, 25th, 50th, 75th, and 90th percent exceedances; the 1-, 7-, and 30-day seasonal mean high flows for the 10-, 25-, and 50-year recurrence intervals; and the 1-, 7-, and 30-day seasonal mean low flows for the 2-, 5-, and 10-year recurrence intervals. Basin and climatic characteristics determined to be significant explanatory variables in one or more regression equations included drainage area, percentage of basin drainage area that drains to isolated lakes and ponds, ruggedness number, stream length, basin compactness ratio, minimum basin elevation, precipitation, slope ratio, stream slope, and soil permeability. The adjusted coefficient of determination for the n-day high-flow regression equations ranged from 55.87 to 94.53 percent. The Chi2 values for the duration regression equations ranged from 13.49 to 117.94, whereas the Chi2 values for the n-day low-flow regression equations ranged from 4.20 to 49.68.

  1. Birthweight percentiles for twin birth neonates by gestational age in China.

    PubMed

    Zhang, Bin; Cao, Zhongqiang; Zhang, Yiming; Yao, Cong; Xiong, Chao; Zhang, Yaqi; Wang, Youjie; Zhou, Aifen

    2016-01-01

    Localized birthweight references for gestational ages serve as an essential tool in accurate evaluation of atypical birth outcomes. Such references for twin births are currently not available in China. The aim of this study was to construct up-to-data sex specific birth weight references by gestational ages for twin births in China. We conducted a population-based analysis on the data of 22,507 eligible living twin infants with births dated between 8/01/2006 and 8/31/2015 from all 95 hospitals within the Wuhan area. Gestational ages in complete weeks were determined using a combination of last-menstrual-period based (LMP) estimation and ultrasound examination. Smoothed percentile curves were created by the Lambda Mu Sigma (LMS) method. Reference of the 3(rd), 10(th), 25(th), 50(th), 75(th), 90(th), 97(th) percentiles birth weight by sex and gestational age were made using 11,861 male and 10,646 female twin newborns with gestational age 26-42 weeks. Separate birthweight percentiles curves for male and female twins were constructed. In summary, our study firstly presents percentile curves of birthweight by gestational age for Chinese twin neonates. Further research is required for the validation and implementation of twin birthweight curves into clinical practice. PMID:27506479

  2. Growth curves for school children from Kuching, Sarawak: a methodological development.

    PubMed

    Bong, Yii Bonn; Shariff, Asma Ahmad; Mohamed, Abdul Majid; Merican, Amir Feisal

    2015-03-01

    In this article, the authors propose reference curves for height and weight for school children in the Kuching area, Sarawak. The school children were from primary to secondary schools (aged 6.5 to 17 years old) and comprised both genders. Anthropometric measurements and demographic information for 3081 school-aged children were collected (1440 boys and 1641 girls). Fitted line plots and percentiles for height and weight (3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentiles) were obtained. The height of school boys and school girls were almost similar at the start of their school-going age. For school girls, height and weight values stabilized when they reached 16 or 17 years old but kept increasing for school boys. School boys were taller than school girls as they entered adolescence. Height differences between school boys and school girls became significantly wider as they grew older. Chinese school children were taller and heavier than those of other ethnic groups. PMID:22652249

  3. Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

    PubMed Central

    Darendeliler, Feyza; Yeşilkaya, Ediz; Bereket, Abdullah; Baş, Firdevs; Bundak, Rüveyde; Sarı, Erkan; Küçükemre Aydın, Banu; Darcan, Şükran; Dündar, Bumin; Büyükinan, Muammer; Kara, Cengiz; Mazıcıoğlu, Mümtaz M.; Adal, Erdal; Akıncı, Ayşehan; Atabek, Mehmet Emre; Demirel, Fatma; Çelik, Nurullah; Özkan, Behzat; Özhan, Bayram; Orbak, Zerrin; Ersoy, Betül; Doğan, Murat; Ataş, Ali; Turan, Serap; Gökşen, Damla; Tarım, Ömer; Yüksel, Bilgin; Ercan, Oya; Hatun, Şükrü; Şimşek, Enver; Ökten, Ayşenur; Abacı, Ayhan; Döneray, Hakan; Özbek, Mehmet Nuri; Keskin, Mehmet; Önal, Hasan; Akyürek, Nesibe; Bulan, Kezban; Tepe, Derya; Emeksiz, Hamdi Cihan; Demir, Korcan; Kızılay, Deniz; Topaloğlu, Ali Kemal; Eren, Erdal; Özen, Samim; Demirbilek, Hüseyin; Abalı, Saygın; Akın, Leyla; Eklioğlu, Beray Selver; Kaba, Sultan; Anık, Ahmet; Baş, Serpil; Ünüvar, Tolga; Sağlam, Halil; Bolu, Semih; Özgen, Tolga; Doğan, Durmuş; Çakır, Esra Deniz; Şen, Yaşar; Andıran, Nesibe; Çizmecioğlu, Filiz; Evliyaoğlu, Olcay; Karagüzel, Gülay; Pirgon, Özgür; Çatlı, Gönül; Can, Hatice Dilek; Gürbüz, Fatih; Binay, Çiğdem; Baş, Veysel Nijat; Sağlam, Celal; Gül, Davut; Polat, Adem; Açıkel, Cengizhan; Cinaz, Peyami

    2015-01-01

    Objective: Children with Turner syndrome (TS) have a specific growth pattern that is quite different from that of healthy children. Many countries have population-specific growth charts for TS. Considering national and ethnic differences, we undertook this multicenter collaborative study to construct growth charts and reference values for height, weight and body mass index (BMI) from 3 years of age to adulthood for spontaneous growth of Turkish girls with TS. Methods: Cross-sectional height and weight data of 842 patients with TS, younger than 18 years of age and before starting any therapy, were evaluated. Results: The data were processed to calculate the 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentile values for defined ages and to construct growth curves for height-for-age, weight-for-age and BMI-for-age of girls with TS. The growth pattern of TS girls in this series resembled the growth pattern of TS girls in other reports, but there were differences in height between our series and the others. Conclusion: This study provides disease-specific growth charts for Turkish girls with TS. These disease-specific national growth charts will serve to improve the evaluation of growth and its management with growth-promoting therapeutic agents in TS patients. PMID:26831551

  4. Birthweight percentiles for twin birth neonates by gestational age in China

    PubMed Central

    Zhang, Bin; Cao, Zhongqiang; Zhang, Yiming; Yao, Cong; Xiong, Chao; Zhang, Yaqi; Wang, Youjie; Zhou, Aifen

    2016-01-01

    Localized birthweight references for gestational ages serve as an essential tool in accurate evaluation of atypical birth outcomes. Such references for twin births are currently not available in China. The aim of this study was to construct up-to-data sex specific birth weight references by gestational ages for twin births in China. We conducted a population-based analysis on the data of 22,507 eligible living twin infants with births dated between 8/01/2006 and 8/31/2015 from all 95 hospitals within the Wuhan area. Gestational ages in complete weeks were determined using a combination of last-menstrual-period based (LMP) estimation and ultrasound examination. Smoothed percentile curves were created by the Lambda Mu Sigma (LMS) method. Reference of the 3rd, 10th, 25th, 50th, 75th, 90th, 97th percentiles birth weight by sex and gestational age were made using 11,861 male and 10,646 female twin newborns with gestational age 26–42 weeks. Separate birthweight percentiles curves for male and female twins were constructed. In summary, our study firstly presents percentile curves of birthweight by gestational age for Chinese twin neonates. Further research is required for the validation and implementation of twin birthweight curves into clinical practice. PMID:27506479

  5. Regression models for estimating herbicide concentrations in U.S. streams from watershed characteristics

    USGS Publications Warehouse

    Larson, S.J.; Gilliom, R.J.

    2001-01-01

    Regression models were developed for estimating stream concentrations of the herbicides alachlor, atrazine, cyanazine, metolachlor, and trifluralin from use-intensity data and watershed characteristics. Concentrations were determined from samples collected from 45 streams throughout the United States during 1993 to 1995 as part of the U.S. Geological Survey's National Water-Quality Assessment (NAWQA). Separate regression models were developed for each of six percentiles (10th, 25th, 50th, 75th, 90th, 95th) of the annual distribution of stream concentrations and for the annual time-weighted mean concentration. Estimates for the individual percentiles can be combined to provide an estimate of the annual distribution of concentrations for a given stream. Agricultural use of the herbicide in the watershed was a significant predictor in nearly all of the models. Several hydrologic and soil parameters also were useful in explaining the variability in concentrations of herbicides among the streams. Most of the regression models developed for estimation of concentration percentiles and annual mean concentrations accounted for 50 percent to 90 percent of the variability among streams. Predicted concentrations were nearly always within an order of magnitude of the measured concentrations for the model-development streams, and predicted concentration distributions reasonably matched the actual distributions in most cases. Results from application of the models to streams not included in the model development data set are encouraging, but further validation of the regression approach described in this paper is needed.

  6. Intraventricular twin fetuses in fetu.

    PubMed

    Huddle, Lauren N; Fuller, Christine; Powell, Tiffany; Hiemenga, Judith A; Yan, Jia; Deuell, Brian; Lyders, Eric M; Bodurtha, Joann N; Papenhausen, Peter R; Jackson-Cook, Colleen K; Pandya, Arti; Jaworski, Margie; Tye, Gary W; Ritter, Ann M

    2012-01-01

    The authors report a rare case of multiple intracranial fetuses in fetu, fulfilling Willis' traditional criteria, which include an axial and appendicular skeleton with surrounding organized tissue. This case was ascertained from studies of a full-term female neonate who presented with ventriculomegaly. A CT scan showed intracranial calcifications that were suggestive of an axial skeleton. Her birth weight was 3.176 kg (50th-75th percentile), length was 52 cm (90th percentile), head circumference was 35 cm (50th-75th percentile), and Apgar scores were 7 and 8 at 1 and 5 minutes, respectively. Prenatal ultrasonography studies performed at 12 weeks and 5 days, and 19 weeks and 6 days revealed normal findings. A 37-week prenatal ultrasonography study showed ventriculomegaly and obstructive hydrocephalus, with a possible intracranial teratoma. Cranial imaging at birth with ultrasonography, CT and MR imaging, and MR angiography demonstrated 2 complex intraventricular masses with cystic, solid, and bony elements. A craniotomy with resection of the masses was performed at 3 months of age. The infant survived and is now 12 months old with some developmental progress. Two axial skeletons, with accompanying rib cage and extremities, including well-formed feet and toes, were noted. Both anencephalic structures had skin with hair, fat, skeletal and smooth muscle, and bony structures with bone marrow and focal areas of calcification. Multiple viscera were present and included thymus, bowel, stomach, salivary gland, kidney, adrenal gland, lung, and presumed adnexal structures. A diagnosis of fetuses in fetu was rendered. Chromosomal studies of the child and tissue from the 2 fetuses in fetu showed normal female karyotypes. A single nucleotide polymorphism array analysis from the proband infant and tissue from the 2 identified fetuses in fetu appeared to be genetically identical. These results are consistent with a monozygotic twin embryonic origin of the fetus in fetu tissue

  7. The 50th Anniversary of the Cahn-Ingold-Prelog Specification of Molecular Chirality.

    PubMed

    Helmchen, Günter

    2016-06-01

    "… Just over 50 years ago, Robert S. Cahn, Sir Christopher Ingold, and Vladimir Prelog published the Review 'Specification of Molecular Chirality' in Angewandte Chemie. The article would change the everyday language of the chemist by bringing the term chirality to their attention. Today, the CIP system is the specification tool in organic chemistry …" Read more in the Editorial by Günter Helmchen. PMID:27151758

  8. The 50th ASMS Conference on Mass Spectrometry and Allied Topics

    PubMed Central

    2002-01-01

    Development of new mass spectrometers and implementation of new analytical methods were the central themes of the conference. The majority of oral presentations and posters were concerned with the application of mass spectrometry to pharmaceutical and biotechnological research. PMID:18629048

  9. A resolution commemorating the 50th Anniversary of the Cape May-Lewes Ferry.

    THOMAS, 113th Congress

    Sen. Coons, Christopher A. [D-DE

    2014-06-26

    06/26/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S4190; text as passed Senate: CR S4165) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  10. A resolution commemorating the 50th anniversary of the Wilderness Act.

    THOMAS, 113th Congress

    Sen. Wyden, Ron [D-OR

    2014-09-18

    09/18/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S5880; text as passed Senate: CR S5799-5800) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  11. 'Focus on Marshall' Features Marshall’s 50th Anniversary

    NASA Video Gallery

    On March 15, 1960, President Dwight Eisenhower issued an executive order designating NASA's first field center as the George C. Marshall Space Flight Center. On the November episode of “Focus on ...

  12. 76 FR 72821 - 50th Anniversary of the United States Agency for International Development

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-28

    ... States of America the two hundred and thirty- sixth. (Presidential Sig.) [FR Doc. 2011-30722 Filed 11-25... 1961, the men and women of USAID have worked on the front lines of poverty and conflict to support... against hunger, poverty, and disease. As USAID continues to shape a brighter future for generations...

  13. 75 FR 76611 - 50th Anniversary of the Arctic National Wildlife Refuge

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-09

    ... of the United States of America the two hundred and thirty-fifth. (Presidential Sig.) [FR Doc. 2010... Wildlife Refuge, I encourage all Americans to recognize the beauty and diversity of all of America's...

  14. The 50th Anniversary of the Thayer Conference: Historical Perspectives and Accomplishments

    ERIC Educational Resources Information Center

    Fagan, Thomas K.

    2005-01-01

    Information from several historical sources provides a clearer understanding of the Thayer Conference, including little-known background information. Changes in school psychology since the conference are described through comparisons of the field at the time of the conference and at present. Major recommendations and expectations emanating from…

  15. A resolution celebrating the 50th anniversary of the 1962 Seattle World's Fair.

    THOMAS, 112th Congress

    Sen. Cantwell, Maria [D-WA

    2012-04-19

    04/19/2012 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S2553-2554) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  16. "The upper limits of vegetation on Mauna Loa, Hawaii": a 50th-anniversary reassessment.

    PubMed

    Juvik, James O; Rodomsky, Brett T; Price, Jonathan P; Hansen, Eric W; Kueffer, Christoph

    2011-02-01

    In January 1958, a survey of alpine flora was conducted along a recently constructed access road across the upper volcanic slopes of Mauna Loa, Hawaii (2525-3397 m). Only five native Hawaiian species were encountered on sparsely vegetated historic and prehistoric lava flows adjacent to the roadway. A resurvey of roadside flora in 2008 yielded a more than fourfold increase to 22 species, including nine native species not previously recorded. Eight new alien species have now invaded this alpine environment, although exclusively limited to a few individuals in ruderal habitat along the roadway. Alternative explanations for species invasion and altitudinal change over the past 50 years are evaluated: (1) changes related to continuing primary succession on ameliorating (weathering) young lava substrates; (2) local climate change; and (3) road improvements and increased vehicular access which promote enhanced car-borne dispersal of alien species derived from the expanding pool of potential colonizers naturalized on the island in recent decades. Unlike alpine environments in temperate latitudes, the energy component (warming) in climate change on Mauna Loa does not appear to be the unequivocal driver of plant invasion and range extension. Warming may be offset by other climate change factors including rainfall and evapotranspiration. PMID:21618930

  17. Physical Modeling of Landslide Generated Tsunamis and the 50th Anniversary of the Vajont Dam Disaster

    NASA Astrophysics Data System (ADS)

    McFall, Brian C.; Mohammed, Fahad; Fritz, Hermann M.

    2013-04-01

    The Vajont river is an affluent of the Piave River located in the Dolomite Alps of the Veneto Region, about 100km north of Venice. A 265.5 m high double curved arch dam was built across a V-shaped gorge creating a reservoir with a maximum storage capacity of 0.169 km3. A maximum water depth of 250 m was reached by early September 1963 during the third filling attempt of the reservoir, but as creeping on the southern flank increased the third reservoir draw down was initiated. By October 9, 1963 the water depth was lowered to 240m as the southern flank of Vajont reservoir catastrophically collapsed on a length of more than 2km. Collapse occurred during reservoir drawdown in a final attempt to reduce flank creeping and the reservoir was only about two-thirds full. The partially submerged rockslide with a volume of 0.24 km3 penetrated into the reservoir at velocities up to 30 m/s. The wave runup in direct prolongation of slide axis reached the lowest houses of Casso 270m above reservoir level before impact corresponding to 245m above dam crest (Müller, 1964). The rockslide deposit came within 50m of the left abutment and towers up to 140m above the dam crest. The lateral spreading of the surge overtopped the dam crest by more than 100m. The thin arch dam withstood the overtopping and sustained no damage to the structural shell and the abutments. The flood wave dropped more than 500m down the Vajont gorge and into the Piave Valley causing utter destruction to the villages of Longarone, Pirago, Villanova, Rivalta and Fae. More than 2000 persons perished. The Vajont disaster highlights an extreme landslide tsunami event in the narrowly confined water body of a reservoir. Landslide tsunami hazards exist even in areas not exposed to tectonic tsunamis. Source and runup scenarios based on real world events are physically modeled in the three dimensional NEES tsunami wave basin (TWB) at Oregon State University (OSU). A novel pneumatic landslide tsunami generator (LTG) was deployed to simulate landslides with varying geometry and kinematics. The LTG consists of a sliding box filled with up to 1,350 kg of naturally rounded river gravel which is accelerated by means of four pneumatic pistons down the 2H: 1V slope, launching the granular landslide towards the water at velocities of up to 5 m/s. Topographical and bathymetric features can greatly affect wave characteristics and runup heights. Landslide tsunamis are studied in different topographic and bathymetric configurations: far field propagation and runup, a narrow fjord and curved headland configurations, and a conical island setting representing landslides off an island or a volcanic flank collapse. Water surface elevations were measured using an array of resistance wave gauges. The granulate landslide shape and front velocity were measured using above and underwater cameras. Three-dimensional landslide surfaces with surface velocities were reconstruction using a stereo particle image velocimetry (PIV) setup. The speckled pattern on the surface of the granular landslide allows for cross-correlation based PIV analysis. Wave runup was measured with resistance wave gauges along the slope and verified with video image processing. The measured landslide and tsunami data serve to validate and advance 3-dimensional numerical landslide tsunami and prediction models.

  18. 77 FR 32873 - Commemoration of the 50th Anniversary of the Vietnam War

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... hundred and thirty-sixth. (Presidential Sig.) [FR Doc. 2012-13514 Filed 5-31-12; 11:15 am] Billing code... home. In the reflection of The Wall, we see the military family members and veterans who carry a...

  19. 77 FR 63203 - 50th Anniversary of the Office of the United States Trade Representative

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... United States Trade Representative (USTR) continues to play a vital role in advancing trade policy that... the United States of America the two hundred and thirty-seventh. (Presidential Sig.) [FR Doc. 2012... Trade Representative By the President of the United States of America A Proclamation On October 11,...

  20. A resolution recognizing the Defense Intelligence Agency on its 50th Anniversary.

    THOMAS, 112th Congress

    Sen. Feinstein, Dianne [D-CA

    2011-03-01

    05/12/2011 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S2970) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  1. The Save-WEFM Case as Reported to the 50th Annual NAEB Convention, 1974.

    ERIC Educational Resources Information Center

    Danna, Sammy R.

    The history of Chicago FM radio station WEFM and the activities of the Citizen's Committee to Save WEFM are chronicled. The focus is principally on the actions of the Citizen's Committee to prevent the conversion of the radio station from a classical music format to rock and roll offerings and to block the sale of the station by Zenith to GCC…

  2. A resolution commemorating the 50th anniversary of the Combined Federal Campaign.

    THOMAS, 112th Congress

    Sen. Akaka, Daniel K. [D-HI

    2011-10-18

    11/16/2011 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (consideration: CR S7627; text as passed Senate: CR S7627) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  3. [The cradle of the Russian radioecology (to the 50th anniversary of the Kyshtym radiation accident)].

    PubMed

    Aleksakhin, R M; Prister, B S

    2008-01-01

    On September 29, 1957, at a nuclear industry facility (Production Association "Mayak"), there was a large radiation accident resulting in the release of radioactive wastes into the environment and the formation of the East-Urals Radioactive Trail (EURT). Within the EURT and there established in 1958 an Experimental Scientific Research Station (ESRS) which came to be known as alma mater of domestic radioecology, various comprehensive long-term investigations had been carried out. The main results of these 50-year investigations have been summarized for a broad range of problems on radionuclide migration in the natural environment and ionizing radiation effects on biota, as well as problems of environmental protection. In addition to the studies of the in situ behavior of released during the accident anthropogenic radionuclides (primarily 90Sr, the main dose-forming radionuclide within the EURT), at the ESRS large experiment have been performed to study migration and biological effects on agricultural plants and animals of man-made radionuclides (especially fresh mixtures of fission products) introduced to the natural environment. Results of ESRS experiments are described on irradiation of natural biogeocenoses from a powerful source of ionizing radiation (1.2 x 10(15) Bq 137Cs). The first unique experience is described of remediation of radioactively contaminated areas with emphasis on agricultural radioecology. The importance of the EURT and ESRS radioecological studies for the development of radioecology as a science is stressed. PMID:18666658

  4. A resolution commemorating the 50th anniversary of the publication of "To Kill a Mockingbird".

    THOMAS, 111th Congress

    Sen. Sessions, Jeff [R-AL

    2010-08-05

    08/05/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6981; text as passed Senate: CR S6981; text of measure as introduced: CR S6908) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  5. Succeed or Else!: Reflections on the 50th Anniversary of the "Journal of Educational Administration"

    ERIC Educational Resources Information Center

    Thomas, A. Ross

    2012-01-01

    Purpose: The purpose of this paper is to identify the key individuals, associations and significant events contributing to the establishment and first 50 years of successful publication of the "Journal of Educational Administration". Design/methodology/approach: This paper is historical in design. Information relevant to its 50 years of…

  6. The 50th Anniversary of "Brown": Is There Any Reason to Celebrate?

    ERIC Educational Resources Information Center

    Eckes, Suzanne E.

    2004-01-01

    The "Brown v. Board of Education" decision remains one of the most important legal decisions in history. Although there were local schemes used to avoid desegregating public schools after the decision, black students experienced declining segregation from the 1950s to the late 1980s. During the 1990s, however, a series of Supreme Court decisions…

  7. Celebrating the 50th anniversary of the American Academy of Psychoanalysis and Dynamic Psychiatry.

    PubMed

    Eckardt, Marianne Horney

    2006-01-01

    On the occasion of its 50 anniversary, the members of the American Academy of Psychoanalysis and Dynamic Psychiatry can look back with pride and be aware that this professional society has been true to its original goal and passionate mission. Thanks for this momentous accomplishment goes to its founding fathers and mothers, who were clear in their purpose and whose wisdom is manifest in the Academy's constitution. In the 1930s, the orthodoxy of the American Psychoanalytic Association created a ferment of rebellion in most of its institutes, which led to secessions, sister institutes, and a greater open-mindedness in institutes residing in Chicago, Washington, New Orleans, and Detroit. The quest for a new national forum that would be open to an exchange of new ideas began in 1951 and culminated in the formation of the American Academy of Psychoanalysis in 1956. The spirit of the Academy is highlighted by relating the successful struggle of communication among its members in a dream workshop that existed for six years. PMID:16548742

  8. Acetylcholinesterase of Schistosoma mansoni--functional correlates. Contributed in honor of Professor Hans Neurath's 90th birthday.

    PubMed

    Arnon, R; Silman, I; Tarrab-Hazdai, R

    1999-12-01

    Acetylcholinesterase (AChE) is an enzyme broadly distributed in many species, including parasites. It occurs in multiple molecular forms that differ in their quaternary structure and mode of anchoring to the cell surface. This review summarizes biochemical and immunological investigations carried out in our laboratories on AChE of the helmint, Schistosoma mansoni. AChE appears in S. mansoni in two principal molecular forms, both globular, with sedimentation coefficients of approximately 6.5 and 8 S. On the basis of their substrate specificity and sensitivity to inhibitors, both are "true" acetylcholinesterases. Approximately half of the AChE activity of S. mansoni is located on the outer surface of the parasite, attached to the tegumental membrane via a covalently attached glycosylphosphatidylinositol anchor. The remainder is located within the parasite, mainly associated with muscle tissue. Whereas the internal enzyme is most likely involved in termination of neurotransmission at cholinergic synapses, the role of the surface enzyme remains to be established; there are, however, indications that it is involved in signal transduction. The two forms of AChE differ in their heparin-binding properties, only the internal 8 S form of the AChE being retained on a heparin column. The two forms differ also in their immunological specificity, since they are selectively recognized by different monoclonal antibodies. Polyclonal antibodies raised against S. mansoni AChE purified by affinity chromatography are specific for the parasite AChE, reacting with both molecular forms, but do not recognize AChE from other species. They interact with the surface-localized enzyme on the intact organism, and produce almost total complement-dependent killing of the parasite. S. mansoni AChE is thus demonstrated to be a functional protein, involved in multifaceted activities, which can serve as a suitable candidate for diagnostic purposes, vaccine development, and drug design. PMID:10631970

  9. [Kallikrein-Kinin System. Long History and Present. (To 90th Anniversary of Discovery of the System)].

    PubMed

    Yarovaya, G A; Neshkova, E A

    2015-01-01

    The kallikrein-kinin system (KKS) is the key proteolytic system participating in control of a wide spectrum of physiological functions and the development of many pathological conditions. This explains great interest in structures, functions and molecular biology of separate components of the system, molecular mechanisms of their interaction and relationship with other regulatory systems. The information in this field for the last two decades clarifies the role of KKS in morphogenesis of cells, regulation of smooth muscular contractility of some organs, decrease of blood pressure, increase of vascular permeability, the development of inflammation, transformation of cells and the other functions of both physiological and pathological processes. Essential progress in understanding of functions KKS was made by the discovery and study of bradykinin receptors, cloning of kininogen and kallikrein encoding genes, revealing of domain structure of kininogen, prekallikrein and some kininases and decoding of mechanisms of contact phase of proteolytic system activation in blood plasma. PMID:26502604

  10. 33 CFR Appendix A to Part 209 - Public Law 90-483, 90th Congress, S. 3710, August 13, 1968

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... non-Federal public body, and be accompanied by an engineering plan if necessary therefor; (2) specify... appropriations hereafter made for civil works not to exceed $10,000,000 for any one fiscal year to carry out...

  11. 33 CFR Appendix A to Part 209 - Public Law 90-483, 90th Congress, S. 3710, August 13, 1968

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... non-Federal public body, and be accompanied by an engineering plan if necessary therefor; (2) specify... appropriations hereafter made for civil works not to exceed $10,000,000 for any one fiscal year to carry out...

  12. [Marine, aviation and space physician, psychologist and physiologist (To the 90th anniversary of the birth of G. M. Zarakovskii)].

    PubMed

    Dvornikov, M V; Medenkov, A A

    2015-04-01

    In the current paper authors discuss problems of marine and aerospace medicine and psychophysiology, which Georgii Zarakovskii (1925-2014), a prominent domestic experts in the field of military medicine, psychology and ergonomics, solved. Authors focused on methodological approaches and results of the study of psychophysiological characteristics and human capabilities took into account for design of tools and organization of flight crews, astronauts and military experts. Authors marked the contribution to the creation of a system integrating psychophysiological features and characteristics of the person neccessary for development, testing and maintenance of aerospace engineering and organization of its professional activities. The possibilities of using the methodology of psychophysiological activity analysis in order to improve the reliability of psychophysiological military specialists, are shown. PMID:26454942

  13. Variability in early communicative development.

    PubMed

    Fenson, L; Dale, P S; Reznick, J S; Bates, E; Thal, D J; Pethick, S J

    1994-01-01

    Data from parent reports on 1,803 children--derived from a normative study of the MacArthur Communicative Development Inventories (CDIs)--are used to describe the typical course and the extent of variability in major features of communicative development between 8 and 30 months of age. The two instruments, one designed for 8-16-month-old infants, the other for 16-30-month-old toddlers, are both reliable and valid, confirming the value of parent reports that are based on contemporary behavior and a recognition format. Growth trends are described for children scoring at the 10th-, 25th-, 50th-, 75th-, and 90th-percentile levels on receptive and expressive vocabulary, actions and gestures, and a number of aspects of morphology and syntax. Extensive variability exists in the rate of lexical, gestural, and grammatical development. The wide variability across children in the time of onset and course of acquisition of these skills challenges the meaningfulness of the concept of the modal child. At the same time, moderate to high intercorrelations are found among the different skills both concurrently and predictively (across a 6-month period). Sex differences consistently favor females; however, these are very small, typically accounting for 1%-2% of the variance. The effects of SES and birth order are even smaller within this age range. The inventories offer objective criteria for defining typicality and exceptionality, and their cost effectiveness facilitates the aggregation of large data sets needed to address many issues of contemporary theoretical interest. The present data also offer unusually detailed information on the course of development of individual lexical, gestural, and grammatical items and features. Adaptations of the CDIs to other languages have opened new possibilities for cross-linguistic explorations of sequence, rate, and variability of communicative development. PMID:7845413

  14. Geochemical signatures of possible deep-seated ore deposits in Tertiary volcanic centers, Arizona and New Mexico, U.S.A.

    USGS Publications Warehouse

    Watts, K.C., Jr.; Hassemer, J.R.

    1989-01-01

    A reconnaissance geochemical survey of stream drainages within 21,000 km2 of southeastern Arizona and southwestern New Mexico shows broad zones of low-level to moderate contrast anomalies, many associated with mid-Tertiary eruptive centers and Tertiary fault zones. Of these eruptive centers, few are known to contain metallic deposits, and most of those known are minor. This, however, may be more a function of shallow erosion level than an indication of the absence of mineralization, since hydrothermal alteration and Fe-Mn-oxide staining are widespread, and geochemical anomalies are pervasive over a larger part of the region than outcrop observations would predict. Accordingly, interpretations of the geochemical data use considerations of relative erosion levels, and inferred element zonalities, to focus on possible undiscovered deposits in the subsurface of base-, precious-, and rare-metal deposits of plutonic-volcanic association. In order to enhance the identification of specific deep targets, we use the empirically determined ratio: Ag+Mn+Pb+Zn+Ba Au+Mo+Cu+Bi+W This ratio is based on reported metal contents of nonmagnetic heavy-mineral samples from the drainage sediment, determined by emission spectrographic analysis. Before the ratio was computed for each sample site, the data were normalized to a previously estimated regional threshold value. A regional isopleth map was then prepared, using a cell-averaging computer routine, with contours drawn at the 25th, 50th, 75th, 80th, 90th, 95th and 99th percentiles of the computed data. ?? 1989.

  15. Influence of Race/Ethnicity, Body Mass Index, and Proximity of Menopause on Menstrual Cycle Patterns in the Menopausal Transition: The Study of Women’s Health Across the Nation (SWAN)

    PubMed Central

    Paramsothy, Pangaja; Harlow, Siobán D.; Elliott, Michael R.; Yosef, Matheos; Lisabeth, Lynda D.; Greendale, Gail A.; Gold, Ellen B.; Crawford, Sybil L.; Randolph, John F.

    2014-01-01

    Objective Few studies evaluate factors that influence menstrual cycle length (MCL) during the menopausal transition (MT), a life-stage during which very long cycles become more likely to occur. The objective of this paper was to assess how BMI and race/ethnicity, factors associated with MCL in young women, influence MCL during the MT. Methods SWAN Menstrual Calendar Substudy data were available from 3 sites (southeastern Michigan, Los Angeles, and northern California) including African-American, White, Chinese, and Japanese women. Self-recorded monthly menstrual calendars with end of the month questions on hormone therapy use and smoking were collected from 1996–2006. Height and weight were measured at annual study visits. We used quantile regression to model MCL at the 25th, 50th, 75th, and 90th percentiles with bootstrap sampling to construct 95% confidence intervals. Models evaluated MCL with time indexed to the start of the MT (n=963) and to the final menstrual period (n=431). Results During the MT, increases in MCL occurred mostly in the right tail of the distribution, reflecting a lengthening of long menstrual cycles not of the median MCL. After adjusting for smoking, education, physical activity, and time, Chinese and Japanese women had 1–6 day longer MCLs as compared to White women. Obese women had 1–5 day longer MCLs as compared to non-obese women. Conclusions As occurs in younger women, menstrual characteristics during the MT are influenced by race/ethnicity and obesity. The long menstrual cycles characteristic of the MT are longer in obese women and in Chinese and Japanese women. PMID:25026113

  16. Comparison of Simulated Workplace Protection Factors Offered by N95 and P100 Filtering Facepiece and Elastomeric Half-Mask Respirators against Particles of 10 to 400 nm

    PubMed Central

    He, Xinjian; Vo, Evanly; Horvatin, M; Liu, Y; Bergman, M; Zhuang, Z

    2015-01-01

    This study compared the simulated workplace protection factors (SWPFs) between NIOSH-approved N95 respirators and P100 respirators, including two models of filtering facepiece respirator (FFR) and two models of elastomeric half-mask respirator (EHR), against sodium chloride particles (NaCl) in a range of 10 to 400 nm. Twenty-five human test subjects performed modified OSHA fit test exercises in a controlled laboratory environment with the N95 respirators (two FFR models and two EHR models) and the P100 respirators (two FFRs and two EHRs). Two Scanning Mobility Particle Sizers (SMPS) were used to measure aerosol concentrations (in the 10–400 nm size range) inside (Cin) and outside (Cout) of the respirator, simultaneously. SWPF was calculated as the ratio of Cout to Cin. The SWPF values obtained from the N95 respirators were then compared to those of the P100 respirators. SWPFs were found to be significantly different (P<0.05) between N95 and P100 class respirators. The 10th, 25th, 50th, 75th and 90th percentiles of the SWPFs for the N95 respirators were much lower than those for the P100 models. The N95 respirators had 5th percentiles of the SWPFs > 10. In contrast, the P100 class was able to generate 5th percentiles SWPFs > 100. No significant difference was found in the SWPFs when tested against nano-size (10 to 100 nm) and large-size (100 to 400 nm) particles. Overall, the findings suggest that the two FFRs and two EHRs with P100 class filters provide better performance than those with N95 filters against particles from 10 to 400 nm, supporting current OSHA and NIOSH recommendations. PMID:26273701

  17. Relationship of adiposity to the population distribution of plasma triglyceride concentrations in vigorously active men and women

    SciTech Connect

    Williams, Paul T.

    2002-12-21

    Context and Objective: Vigorous exercise, alcohol and weight loss are all known to increase HDL-cholesterol, however, it is not known whether these interventions raise low HDL as effectively as has been demonstrated for normal HDL. Design: Physician-supplied medical data from 7,288 male and 2,359 female runners were divided into five strata according to their self-reported usual running distance, reported alcohol intake, body mass index (BMI) or waist circumference. Within each stratum, the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles for HDL-cholesterol were then determined. Bootstrap resampling of least-squares regression was applied to determine the cross-sectional relationships between these factors and each percentile of the HDL-cholesterol distribution. Results: In both sexes, the rise in HDL-cholesterol per unit of vigorous exercise or alcohol intake was at least twice as great at the 95th percentile as at the 5th percentile of the HDL-distribution. There was also a significant graded increase in the slopes relating exercise (km run) and alcohol intake to HDL between the 5th and the 95th percentile. Men's HDL-cholesterol decreased in association with fatness (BMI and waist circumference) more sharply at the 95th than at the 5th percentile of the HDL-distribution. Conclusions: Although exercise, alcohol and adiposity were all related to HDL-cholesterol, the elevation in HDL per km run or ounce of alcohol consumed, and reduction in HDL per kg of body weight (men only), was least when HDL was low and greatest when HDL was high. These cross-sectional relationships support the hypothesis that men and women who have low HDL-cholesterol will be less responsive to exercise and alcohol (and weight loss in men) as compared to those who have high HDL-cholesterol.

  18. An Examination of Growth in Vocabulary and Phonological Awareness in Early Childhood: An Individual Growth Model Approach

    ERIC Educational Resources Information Center

    Cassano, Christina Marie

    2013-01-01

    The present study used individual growth modeling to examine the role of specific forms (i.e., receptive, expressive, and definitional vocabulary and grammatical skill) and levels of oral vocabulary skill (i.e., 25th, 50th, or 75th percentile) in phonological awareness growth during the preschool and kindergarten years. Sixty-one,…

  19. Effectiveness of Intelligent Tutoring Systems: A Meta-Analytic Review

    ERIC Educational Resources Information Center

    Kulik, James A.; Fletcher, J. D.

    2016-01-01

    This review describes a meta-analysis of findings from 50 controlled evaluations of intelligent computer tutoring systems. The median effect of intelligent tutoring in the 50 evaluations was to raise test scores 0.66 standard deviations over conventional levels, or from the 50th to the 75th percentile. However, the amount of improvement found in…

  20. 90-50-10 Celebration: Ernest Courant

    SciTech Connect

    Ernest Courant

    2010-06-10

    BNL hosts a celebration titled “90-50-10” to celebrate the 90th birthday of Ernest Courant (of “strong focusing” fame), the 50th anniversary of the startup of the Alternating Gradient Synchrotron (AGS, home of three Nobel Prizes), and the 10th anniversary of first collisions at the Relativistic Heavy Ion Collider (RHIC).

  1. 90-50-10 Celebration: Ernest Courant

    ScienceCinema

    Ernest Courant

    2010-09-01

    BNL hosts a celebration titled ?90-50-10? to celebrate the 90th birthday of Ernest Courant (of ?strong focusing? fame), the 50th anniversary of the startup of the Alternating Gradient Synchrotron (AGS, home of three Nobel Prizes), and the 10th anniversary of first collisions at the Relativistic Heavy Ion Collider (RHIC).

  2. Effects of body size and nutritional regimen on survival in adult Aedes albopictus (Diptera: Culicidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The effects of adult body size and nutritional regimen on the mean time to death (LT) for the 50th (LT50) and 90th centiles (LT90) of large and small male and female Aedes albopictus (Skuse) was determined in the laboratory. The estimated LT50 and the LT90 for large/small females was significantly ...

  3. Characterization of selected biological, chemical, and physical conditions at fixed sites in the Upper Colorado River basin, Colorado, 1995-98

    USGS Publications Warehouse

    Deacon, Jeffrey R.; Mize, Scott V.; Spahr, Norman E.

    1999-01-01

    at mining land-use sites than at the background site and were less than the 50th percentile of those for sites from the three other NAWQA study units. Nutrient concentrations at urban and recreation sites in the Southern Rocky Mountain physiographic province generally were greater than concentrations at the background site and generally were between the 25th and 90th percentile of concentrations for sites from the three other NAWQA study units. Habitat conditions and fish communities at urban and recreation sites were slightly degraded compared to the background site. EPT richness and the percentage of EPT were lower at urban and recreation sites than at the background site and were between the 25th and 75th percentile of those for sites from the three other NAWQA study units. The percentage of Chironomidae, which may be indicative of pollutant-tolerant organisms, was higher at urban and recreation sites than at the background site. Mixed land-use sites in the Southern Rocky Mountains physiographic province had similar nutrient concentrations and similar cadmium and zinc streambed-sediment concentrations. Fish-community degradation index values were very different among the three mixed land-use sites in the Southern Rocky Mountains physiographic province. Larger percentages of omnivores and anomalies such as lesions and deformities at two mixed land-use sites resulted in higher degradation values of the fish community. Agriculture land-use sites had higher concentrations of nutrients and selenium than the background site in the Colorado Plateau physiographic province. Concentrations of p,p'-DDE in fish tissue at agriculture sites were higher than the 75th percentile of concentrations for sites from the three other NAWQA study units. Fish communities had degradation values near the 75th percentile for agriculture sites. The percentage of EPT was low at agriculture sites when compared to the background site. Two mixed land-use sites in the Colorado Plateau physiographi

  4. EDITORIAL: Special issue in honour of J E Allen's 75th birthday

    NASA Astrophysics Data System (ADS)

    Franklin, R. N.

    2003-11-01

    This issue of Journal of Physics D: Applied Physics is dedicated to Professor John Allen who has spent most of his professional life in the Department of Engineering Science, Oxford University, working on problems in gas discharges and plasma physics. His first degrees and doctorate were taken at Liverpool University in the 1950s where at the time there was an internationally renowned group led by Meek, Craggs and Edels. He then spent some time at Frascati in Italy on secondment from Harwell, helping to build up expertise there. He returned to England in the mid-1960s, first to Cambridge, but he soon migrated to Oxford to University College and the Department of Engineering Science to strengthen a team that already included von Engel, Motz and Woods with more recent reinforcement by Howatson and myself. Thus there was built up both a post-graduate MSc course and what amounted to a graduate school producing many scientists who have since distinguished themselves in all parts of the world. The prospects for success in the quest for fusion and the proximity of Culham Laboratory produced a heady mix. But the timescales lengthened and fashions changed. However, John moved with the times and he and his research students made notable contributions to the understanding of dusty plasmas and to radio-frequency plasmas used in the processing of microchips. The structure at Oxford was such that the recognition of a professorship came late in his career, but his international reputation was well established much earlier. Being freed of tutorial duties he has travelled much in recent years and has been Chairman of the International Conference on Phenomena in Ionized Gases (ICPIG) 1999-2001 and directly involved in the international effort to carry out dusty plasma experiments in space under micro-gravity conditions. For my part, having known John as a colleague over the past forty years, he has been a valuable point of reference when one needed someone to comment on new ideas, a challenging competitor when we were working on similar lines, and his research students provided me with the stimulation that comes from such interaction, be it informal or more formally in the course of D Phil vivas. Thus I have felt that there was a debt to be repaid by encouraging his students and other co-workers to contribute to this issue. More importantly, we honour someone whose contributions we know will stand the test of time.

  5. A resolution commemorating the 75th Anniversary of Air Force Weather.

    THOMAS, 112th Congress

    Sen. Johanns, Mike [R-NE

    2012-08-02

    08/02/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6012-6013; text as passed Senate: CR S6012; text of measure as introduced: CR S5992) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  6. Symposium for Alfred Wolf's 75th birthday at American Chemical Society meeting

    SciTech Connect

    1998-04-02

    This report contains abstracts from the symposium presented by the Division of Nuclear Chemistry and Technology of the American Chemical Society. Sessions covered the following topics: Therapeutic radionuclides--Making the right choice; Aspects of nuclear science; Nuclear structure with large gamma-ray detector arrays and their auxiliary devices; Thirty years of research in nuclear dynamics--From fission to the quark-gluon plasma; Chelated metal ions for diagnosis and therapy; Radiochemistry--Basic and applied; and Applications of small accelerators in science and industry.

  7. A resolution congratulating the Soil Science Society of America on its 75th anniversary.

    THOMAS, 112th Congress

    Sen. Moran, Jerry [R-KS

    2011-06-30

    06/30/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S4304-4305; text as passed Senate: CR S4304-4305; text of measure as introduced: CR S4298) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  8. A concurrent resolution commemorating the 75th anniversary of the dedication of Shenandoah National Park.

    THOMAS, 112th Congress

    Sen. Webb, Jim [D-VA

    2011-06-23

    06/23/2011 Referred to the Committee on Energy and Natural Resources. (text of measure as introduced: CR S4104) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. A resolution commemorating the 75th anniversary of the dedication of Shenandoah National Park.

    THOMAS, 112th Congress

    Sen. Webb, Jim [D-VA

    2011-09-08

    09/08/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR: S5465; text as passed Senate: CR S5465; text of measure as introduced: CR S5463) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  10. A resolution commemorating the 75th anniversary of Kristallnacht, or the Night of the Broken Glass.

    THOMAS, 113th Congress

    Sen. Cardin, Benjamin L. [D-MD

    2013-11-12

    11/12/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S7964; text as passed Senate: CR S7962) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  11. Landau ghost pole problem in quantum field theory: From 50th of last century to the present day

    NASA Astrophysics Data System (ADS)

    Jafarov, Rauf G.; Mutallimov, Mutallim M.

    2016-03-01

    In this paper we present our results of the investigation of asymptotical behavior of amplitude at short distances in four-dimensional scalar field theory with ϕ4 interaction. To formulate of our calculating model - two-particle approximation of the mean-field expansion we have used an Rochev's iteration scheme of solution of the Schwinger-Dyson equations with the fermion bilocal source. We have considered the nonlinear integral equations in deep-inelastic region of momenta. As result we have a non-trivial behavior of amplitude at large momenta.

  12. Remembering Charles B. Huggins' Nobel Prize for Hormonal Treatment of Prostatic Cancer at its 50th Anniversary.

    PubMed

    Hansson, Nils; Moll, Friedrich; Schultheiss, Dirk; Krischel, Matthis

    2016-06-01

    Charles B. Huggins received the Nobel Prize in 1966. Based on archival sources from the Nobel archive we have found that nominators emphasised the practical therapeutic applications of his discoveries that were showing 25 yr after his key publications. PMID:26838478

  13. 3 CFR 8759 - Proclamation 8759 of November 21, 2011. 50th Anniversary of the United States Agency for...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... developing world and the American people. Since President John F. Kennedy founded USAID in 1961, the men and... countries as they build a better future. By promoting sustainable growth in the developing world, we spur... conflict around the world. Even after these successes, we know there is more to do. To advance...

  14. A resolution recognizing the 50th anniversary of the sinking of the U.S.S. Thresher (SSN 593).

    THOMAS, 113th Congress

    Sen. Shaheen, Jeanne [D-NH

    2013-04-09

    04/09/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2508; text as passed Senate: CR S2507) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  15. Happy 50th Birthday Smokey Bear! A Learning Kit about Forests and Fire Safety for Grades K-3.

    ERIC Educational Resources Information Center

    Hall, Meryl

    For over 50 years, the primary goal of Smokey Bear has been to introduce the forest fire prevention message to young children. This learning kit provides the K-3 teacher with activities and resources to help students learn about Smokey Bear and fire safety, about forests as habitats, and about what they can do to protect forests. Students are…

  16. Dosimetric impacts of microgravity: an analysis of 5th, 50th and 95th percentile male and female astronauts

    NASA Astrophysics Data System (ADS)

    Bahadori, Amir A.; Van Baalen, Mary; Shavers, Mark R.; Semones, Edward J.; Bolch, Wesley E.

    2012-02-01

    Computational phantoms serve an important role in organ dosimetry and risk assessment performed at the National Aeronautics and Space Administration (NASA). A previous study investigated the impact on organ dose equivalents and effective doses from the use of the University of Florida hybrid adult male (UFHADM) and adult female (UFHADF) phantoms at differing height and weight percentiles versus those given by the two existing NASA phantoms, the computerized anatomical man (CAM) and female (CAF) (Bahadori et al 2011 Phys. Med. Biol. 56 1671-94). In the present study, the UFHADM and UFHADF phantoms of different body sizes were further altered to incorporate the effects of microgravity. Body self-shielding distributions are generated using the voxel-based ray tracer (VoBRaT), and the results are combined with depth dose data from the NASA codes BRYNTRN and HZETRN to yield organ dose equivalents and their rates for a variety of space radiation environments. It is found that while organ dose equivalents are indeed altered by the physiological effects of microgravity, the magnitude of the change in overall risk (indicated by the effective dose) is minimal for the spectra and simplified shielding configurations considered. The results also indicate, however, that UFHADM and UFHADF could be useful in designing dose reduction strategies through optimized positioning of an astronaut during encounters with solar particle events.

  17. Reflections on the 50th Anniversary of the Landmark Decision. Brown v. Board of Education. Info Brief. Number 37

    ERIC Educational Resources Information Center

    Laitsch, Dan; Rodi, Katherine G.

    2004-01-01

    In the 50 years since "Brown v. Board of Education of Topeka" formally desegregated public schools, there has been enormous progress in the academic success of African Americans, particularly in high school completion, improved test scores, increased college enrollment, and attainment of advanced degrees, as well as full access to and…

  18. A resolution commemorating John Lewis on the 50th anniversary of his chairmanship of the Student Nonviolent Coordinating Committee.

    THOMAS, 113th Congress

    Sen. Isakson, Johnny [R-GA

    2013-06-13

    06/19/2013 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  19. The 50th Anniversary of Brown v. Board of Education: Continued Impacts on Minority Life Science Education

    ERIC Educational Resources Information Center

    Ricks, Irelene

    2004-01-01

    This article provides a brief history of affirmative action in the United States. The author describes the impact of the "Brown v. Board of Education" on minority life science education. She also discusses how The American Society for Cell Biology (ASCB) Minorities Affairs Committee (MAC) can improve the minority science pipeline. (Contains 1…

  20. Happy 50th, Smokey Bear! A Learning Kit about Forests and Fire Safety for Grades K-3.

    ERIC Educational Resources Information Center

    Hall, Meryl

    In 1994, Smokey Bear turns 50! For a half century, Smokey has been helping children and adults protect forests and wildlands from careless fire. With this kit students can celebrate Smokey's message using a variety of activities that include dramatic play, stories, games, and things to make and do. Through these activities, students learn about…

  1. 3 CFR 8886 - Proclamation 8886 of October 9, 2012. 50th Anniversary of the Office of the United States Trade...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... strategy for an economy built to last. On this anniversary, we recognize the dedicated professionals who... best place in the world to innovate, invest, work, and build a business. NOW, THEREFORE, I,...

  2. 3 CFR 9004 - Proclamation 9004 of August 23, 2013. 50th Anniversary of the March on Washington for Jobs and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., white, Latino, Asian, and Native American—woven together like a great American tapestry, sharing in the dream that our Nation would one day make real the promise of liberty, equality, and justice for all. The...; when one American gets a raw deal, it jeopardizes justice for everyone. These are lessons we...

  3. SPECIAL ISSUE DEVOTED TO THE 90TH ANNIVERSARY OF A.M. PROKHOROV: Formation and development dynamics of femtosecond laser microplasma in gases

    NASA Astrophysics Data System (ADS)

    Bukin, V. V.; Vorob'ev, Nikolai S.; Garnov, Sergei V.; Konov, Vitalii I.; Lozovoi, V. I.; Malyutin, A. A.; Shchelev, M. Ya; Yatskovskii, I. S.

    2006-07-01

    We report our experimental investigations of the formation and development dynamics of laser plasma produced in gas microvolumes (microplasma) upon multiple ionisation by tightly focused (to a spot 2—3 μm in diameter) high-intensity (up to ≈1017 W cm-2) femtosecond pulses of a Ti:sapphire laser (τp ⋍ 130 fs, λ = 800 nm). Precision interferometric measurements (with a spatial resolution of ≈1.5 μm) were made of the spatiotemporal distribution of the refractive index and electron density in the microplasmas of the air and helium immediately during the action of the exciting femtosecond laser pulse and at the initial stage of free plasma expansion. The microplasma formation was shown to occur as a result of almost complete (up to bare nuclei) ionisation of the initial gas. For the first time the spectral continuum and the dynamics of spectral line formation in the UV and visible spectral ranges were investigated with a picosecond time resolution for the femtosecond laser-produced microplasmas of the air, N2, Ar, and He at normal conditions. For the first time the generation of the second (even) laser radiation harmonic was recorded in a femtosecond subcritical-density plasma of gases.

  4. PAPERS DEVOTED TO THE 90TH ANNIVERSARY OF A.M.PROKHOROV: Lasing properties of selectively pumped Raman-active Nd3+-doped molybdate and tungstate crystals

    NASA Astrophysics Data System (ADS)

    Basiev, Tasoltan T.; Doroshenko, Maxim E.; Ivleva, Lyudmila I.; Osiko, Vyacheslav V.; Kosmyna, M. B.; Komar', V. K.; Sulc, J.; Jelinkova, H.

    2006-08-01

    The lasing efficiency of Nd3+ ions is studied in laser materials capable of self-Raman frequency conversion. The lasing properties of tungstate and molybdate crystals with the scheelite structure (SrWO4, BaWO4, PbWO4, SrMoO4, PbMoO4) activated with neodymium ions are investigated upon longitudinal pumping by a 750-nm alexandrite laser or a 800-nm diode laser. The slope lasing efficiency obtained for a Nd3+:PbMoO4 laser emitting at 1054 nm is 54.3% for the total lasing efficiency of 46%, which is the best result for all the crystals with the scheelite structure studied so far. The simultaneous Q-switched lasing and self-Raman frequency conversion were demonstrated in neodymium-doped SrWO4, PbWO4, and BaWO4 crystals.

  5. SPECIAL ISSUE DEVOTED TO THE 90TH ANNIVERSARY OF A.M. PROKHOROV: Neodymium-doped graded-index single-crystal fibre lasers

    NASA Astrophysics Data System (ADS)

    Bufetova, G. A.; Kashin, V. V.; Nikolaev, D. A.; Rusanov, S. Ya; Seregin, V. F.; Tsvetkov, V. B.; Shcherbakov, Ivan A.; Yakovlev, A. A.

    2006-07-01

    The efficient technology is developed for growing high-quality doped single-crystal fibres by the mini-pedestal method with laser heating. The technology can be used to fabricate high-quality doped single-crystal fibres with a controllable radial gradient of the refractive index. The refractive-index profile in single-crystal fibres is studied experimentally. The efficient operation of a Nd3+ : YAG single-crystal fibre laser in the waveguide regime was demonstrated upon longitudinal pumping by a laser diode.

  6. Update of Watershed Regressions for Pesticides (WARP) for Predicting Atrazine Concentration in Streams

    USGS Publications Warehouse

    Stone, Wesley W.; Gilliom, Robert J.

    2009-01-01

    Regression models for predicting atrazine concentrations in streams were updated by incorporating refined annual atrazine-use estimates and by adding an explanatory variable representing annual precipitation characteristics. The updated Watershed Regressions for Pesticides (WARP) models enable improved predictions of specific pesticide-concentration statistics for unmonitored streams. for unmonitored streams. Separate WARP regression models were derived for selected percentiles (5th, 10th, 15th, 25th, 50th, 75th, 85th, 90th and 95th), annual mean, annual maximum, and annual maximum moving-average (21-, 60-, and 90-day durations) concentration statistics. Development of the regression models involved the same model-development data, model-validation data, and regression methods as those used in the original development of WARP. The original WARP models were based on atrazine-use estimates from either 1992 or 1997. This update of the WARP models incorporates annual atrazine-use estimates. In addition, annual precipitation data were evaluated as potential explanatory variables. as potential explanatory variables. The updated WARP models include the same five explanatory variables and transformations that were used in the original WARP models, including the new annual atrazine-use data. The models also include a sixth explanatory variable, total precipitation during May and June of the year of sampling. The updated WARP models account for as much as 82 percent of the variability in the concentration statistics among the 112 sites used for model development, whereas previous WARP models accounted for no more than 77 percent. Concentration statistics predicted by the 95th percentile, annual mean, annual maximum and annual maximum moving-average concentration models were within a factor of 10 of the observed concentration statistics for most of the model development and validation sites. Overall, performance of the models for the development and validation sites supports

  7. BMI, Waist Circumference Reference Values for Chinese School-Aged Children and Adolescents

    PubMed Central

    Song, Peige; Li, Xue; Gasevic, Danijela; Flores, Ana Borges; Yu, Zengli

    2016-01-01

    Background: Childhood obesity has become one of the most serious public health challenges in the 21st century in most developing countries. The percentile curve tool is useful for monitoring and screening obesity at population level, however, in China, no official recommendations on childhood body mass index (BMI) and waist circumference (WC) reference percentiles have been made in practice. Aims: to construct the percentile reference values for BMI and WC, and then to calculate the prevalence of overall and abdominal obesity for Chinese children and adolescents. Methods: A total of 5062 anthropometric records for children and adolescents aged from 7 to 18 years (2679 boys and 2383 girls) were included for analysis. The participants were recruited as part of the national representative “China Health and Nutrition Survey” (CHNS). Age, gender, weight, height, and WC were assessed. Smoothed BMI and WC percentile curves and values for the 3rd, 5th, 10th, 15th, 25th, 50th, 75th, 85th, 90th, 95th and 97th percentiles were constructed by using the Lambda-Mu-Sigma (LMS) method. The prevalence estimates of the overall and abdominal obesity were calculated by using the cut-offs from our CHNS study and the previous “Chinese National Survey on Students’ Constitution and Health” (CNSSCH) study, respectively. The difference between prevalence estimates was tested by a McNemar test, and the agreement between these prevalence estimates was calculated by using the Cohen’s kappa coefficient. Results: The prevalence values of overall obesity based on the cut-offs from CHNS and CNSSCH studies were at an almost perfect agreement level in boys (κ = 0.93). However, among girls, the overall obesity prevalence differed between the studies (p < 0.001) and the agreement was weaker (κ = 0.76). The abdominal obesity prevalence estimates were significant different according to the two systems both in boys and girls, although the agreement reached to 0.88, which represented an

  8. Vigorous exercise and the population distribution of bodyweight

    SciTech Connect

    Williams, Paul T.

    2002-09-18

    Background: While the benefits of vigorous exercise on body weight and regional adiposity are well established, whether these benefits affect equally the highest and lowest portions of the weight distribution has not been previously reported. The impact of exercise on the more extreme body weights and body circumferences is clinically important because these values represent individuals at greatest health risk. Method: We divided self-reported weights and body circumferences from a cross-sectional sample of 7,288 male and 2,359 female runners into five strata according to the distances run per week and within each stratum determined the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles. Then Least-squares regression was then employed at each percentile to determine the dose-response relationship between running distance and adiposity. Results: Per kilometer run per week, the associated decline for body mass index (BMI) was three-fold greater at the 95th than at the 5th percentile in men, and nine-fold greater at the 95th than the 5th percentile in women (all P<0.001). Reported waist circumference also declined more sharply at the 95th percentile than at the 5th percentile in men (-0.13/261 0.02 versus -0.06 plus or minus 0.01 cm per km/wk) and women (-0.18 plus or minus 0.04 versus -0.05 plusor minus 0.01 cm per km/wk). In women, both hip and chest circumferences declined more sharply per kilometer run at the 95th percentile than at the 5th percentile. Conclusions: These results support the hypothesis that running promotes the greatest weight loss specifically in those individuals who have the most to gain from losing weight. Comparisons based on average BMI or average body circumferences are likely to underestimate the health benefits of running because of the J-shaped relationship between adiposity and mortality. Whether the observed associations are primarily due to exercise-induced weight loss or self-selection remains to be determined.

  9. Distributions of median nutrient and chlorophyll concentrations across the Red River Basin, USA.

    PubMed

    Longing, D; Haggard, B E

    2010-01-01

    Acquisition and compilation of water-quality data for an 11-yr time period (1996-2006) from 589 stream and river stations were conducted to support nutrient criteria development for the multistate Red River Basin shared by Arkansas, Louisiana, New Mexico, Oklahoma, and Texas. Ten water-quality parameters were collected from six data sources (USGS, Arkansas Department of Environmental Quality, Louisiana Department of Environmental Quality, Oklahoma Conservation Commission, Oklahoma Water Resources Board, and Texas Commission on Environmental Quality), and an additional 13 parameters were acquired from at least one source. Median concentrations of water-quality parameters were calculated at each individual station and frequency distributions (minimum, 10th, 25th, 50th, 75th, 90th percentiles, and maximum) of the median concentrations were calculated. Across the Red River Basin, median values for total nitrogen (TN), total phosphorus (TP), and sestonic chlorophyll-a (chl-a) ranged from < 0.02 to 20.2 mg L(-1), < 0.01 to 6.66 mg L(-1), and 0.10 to 262 microg L(-1), respectively. Overall, the 25th percentiles of TN data specific to the Red River Basin were generally similar to the USEPA-recommended ecoregion nutrient criteria of 0.31 to 0.88 mg L(-1), whereas median TP and chl-a data specific to the Red River Basin showed 25th percentiles higher than the USEPA-recommended criteria (0.010-0.067 mg TP L(-1); 0.93-3.00 microg chl-a L(-1)). The unique location of the Red River Basin in the south-central United States places it near the boundaries of several aggregate ecoregions; therefore, the development of ecoregion nutrient criteria likely requires using data specific to the Red River Basin, as shown in these analyses. This study provided basin-specific frequency distribution of median concentrations of water-quality parameters as the first step to support states in developing nutrient criteria to protect designated uses in the multijurisdictional Red River Basin. PMID

  10. Gestational weight gain standards based on women enrolled in the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project: a prospective longitudinal cohort study

    PubMed Central

    Bishop, Deborah C; Pang, Ruyan; Ohuma, Eric O; Kac, Gilberto; Abrams, Barbara; Rasmussen, Kathleen; Barros, Fernando C; Hirst, Jane E; Lambert, Ann; Papageorghiou, Aris T; Stones, William; Jaffer, Yasmin A; Altman, Douglas G; Noble, J Alison; Giolito, Maria Rosa; Gravett, Michael G; Purwar, Manorama; Kennedy, Stephen H; Bhutta, Zulfiqar A; Villar, José

    2016-01-01

    Objective To describe patterns in maternal gestational weight gain (GWG) in healthy pregnancies with good maternal and perinatal outcomes. Design Prospective longitudinal observational study. Setting Eight geographically diverse urban regions in Brazil, China, India, Italy, Kenya, Oman, United Kingdom, and United States, April 2009 to March 2014. Participants Healthy, well nourished, and educated women enrolled in the Fetal Growth Longitudinal Study component of the INTERGROWTH-21st Project, who had a body mass index (BMI) of 18.50-24.99 in the first trimester of pregnancy. Main outcome measures Maternal weight measured with standardised methods and identical equipment every five weeks (plus/minus one week) from the first antenatal visit (<14 weeks’ gestation) to delivery. After confirmation that data from the study sites could be pooled, a multilevel, linear regression analysis accounting for repeated measures, adjusted for gestational age, was applied to produce the GWG values. Results 13 108 pregnant women at <14 weeks’ gestation were screened, and 4607 met the eligibility criteria, provided consent, and were enrolled. The variance within sites (59.6%) was six times higher than the variance between sites (9.6%). The mean GWGs were 1.64 kg, 2.86 kg, 2.86 kg, 2.59 kg, and 2.56 kg for the gestational age windows 14-18+6 weeks, 19-23+6 weeks, 24-28+6 weeks, 29-33+6 weeks, and 34-40+0 weeks, respectively. Total mean weight gain at 40 weeks’ gestation was 13.7 (SD 4.5) kg for 3097 eligible women with a normal BMI in the first trimester. Of all the weight measurements, 71.7% (10 639/14 846) and 94.9% (14 085/14 846) fell within the expected 1 SD and 2 SD thresholds, respectively. Data were used to determine fitted 3rd, 10th, 25th, 50th, 75th, 90th, and 97th smoothed GWG centiles by exact week of gestation, with equations for the mean and standard deviation to calculate any desired centiles according to gestational age in exact weeks. Conclusions

  11. [Dr. Piotr Borsukiewicz--one of the pleiad of physicians in Lublin (the 75th anniversary of his death)].

    PubMed

    Staszyc, J

    1992-01-01

    Seventy years have passed since the death of dr Piotr Borsukiewicz. He spent 9 out of his 22 years of work in Lublin (1909-1918) being the head of the paediatric hospital (1911-1918), the member of the Lublin Medical Society, the president and vice president of some other public service organizations and inscribed himself in letters of gold in the history of medicine and people of Lublin. He worked and lived in the difficult years of two wars (1904-1905 and 1914-1918), the rapid development of medical sciences and the separation of medical specialties. His diligence, loyalty to the Hippocratic code and the instructions of dr W. Biegański as well as to the patriotic dictates resulted in the union of the meaning of his own existence with the deep belief in man and the favourite work as a physician. Helping the poor and those in need he contracted spotted fever but belittled his complaints and died on April 12, 1918 in Lublin. He left us the special patterns of the ideal medical care which are still alive today, so non omnis moriar. PMID:1365791

  12. 3 CFR 8546 - Proclamation 8546 of August 13, 2010. 75th Anniversary of the Social Security Act

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the United States of America A Proclamation On August 14, 1935, President Franklin D. Roosevelt signed... poverty-ridden old age.” Our Nation was entrenched in the Great Depression. Unemployment neared 20 percent... will not live in poverty. My Administration is committed to strengthening our retirement system...

  13. In Diversity Is Strength: Capitalizing on the New Work Force. 75th Anniversary Symposia Series. Report Number 994.

    ERIC Educational Resources Information Center

    Alster, Judith, Ed.; And Others

    This document, which is based on a symposium devoted to capitalizing on the new work force, contains five reports describing how major U.S. corporations are dealing with the demographic changes currently under way in the United States. "Whither the Work Force?" (Delores Wolf) discusses the proper role of corporations in coping with a lack of…

  14. Ninety day toxicity and toxicokinetics of fluorochloridone after oral administration in rats.

    PubMed

    Zhang, Suhui; Cheng, Xiaoqin; Wang, Yu; Fan, Junpei; Li, Rui; Zhou, Su; Liu, Shihong; Shi, Jingmin; Sun, Jie; Hu, Yue; Xu, Chaojin; Wu, Chunhua; Chang, Xiuli; Tang, Liming; Zhou, Zhijun

    2015-05-01

    The ninety day toxicity and toxicokinetics of fluorochloridone (FLC) were accessed in Wistar rats. Animals were gavaged with FLC at doses of 31.25 mg/kg, 125 mg/kg and 500 mg/kg for ninety days, followed by thirty days for recovery. On the 1st, 60th, 75th and 90th days of the dosing phase, plasma of ten animals of all groups treated with FLC was collected for toxicokinetic analysis of FLC by an UPLC-MS/MS method. Numerous changes in body weight, hematology, serum chemistry, and organ weight ratios were observed by the 45th and 90th dosing day. Most changes in groups treated with FLC were absent on the last recovery day. Testis and epididymis lesions were consistently seen in histopathological observations on the 45th, 90th dosing day and the last recovery day. Repeated administration of FLC increased the level of testosterone in serum in male rats on the 90th dosing day. FLC plasma concentrations could be detected in all animal drug-treated groups during the dosing phase, and a dose proportional relationship was seen between FLC dose and AUC or Cmax. This study will support future studies on the mechanism of FLC-induced toxicity. PMID:25955529

  15. Ninety Day Toxicity and Toxicokinetics of Fluorochloridone after Oral Administration in Rats

    PubMed Central

    Zhang, Suhui; Cheng, Xiaoqin; Wang, Yu; Fan, Junpei; Li, Rui; Zhou, Su; Liu, Shihong; Shi, Jingmin; Sun, Jie; Hu, Yue; Xu, Chaojin; Wu, Chunhua; Chang, Xiuli; Tang, Liming; Zhou, Zhijun

    2015-01-01

    The ninety day toxicity and toxicokinetics of fluorochloridone (FLC) were accessed in Wistar rats. Animals were gavaged with FLC at doses of 31.25 mg/kg, 125 mg/kg and 500 mg/kg for ninety days, followed by thirty days for recovery. On the 1st, 60th, 75th and 90th days of the dosing phase, plasma of ten animals of all groups treated with FLC was collected for toxicokinetic analysis of FLC by an UPLC-MS/MS method. Numerous changes in body weight, hematology, serum chemistry, and organ weight ratios were observed by the 45th and 90th dosing day. Most changes in groups treated with FLC were absent on the last recovery day. Testis and epididymis lesions were consistently seen in histopathological observations on the 45th, 90th dosing day and the last recovery day. Repeated administration of FLC increased the level of testosterone in serum in male rats on the 90th dosing day. FLC plasma concentrations could be detected in all animal drug-treated groups during the dosing phase, and a dose proportional relationship was seen between FLC dose and AUC or Cmax. This study will support future studies on the mechanism of FLC-induced toxicity. PMID:25955529

  16. Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995–2011

    PubMed Central

    Peckham, Erin C.; Scheurer, Michael E.; Danysh, Heather E.; Lubega, Joseph; Langlois, Peter H.; Lupo, Philip J.

    2015-01-01

    There is warranted interest in assessing the association between residential radon exposure and the risk of childhood cancer. We sought to evaluate the association between residential radon exposure and the incidence of childhood lymphoma in Texas. The Texas Cancer Registry (n = 2147) provided case information for the period 1995–2011. Denominator data were obtained from the United States Census. Regional arithmetic mean radon concentrations were obtained from the Texas Indoor Radon Survey and linked to residence at diagnosis. Exposure was assessed categorically: ≤25th percentile (reference), >25th to ≤50th percentile, >50th to ≤75th percentile, and >75th percentile. Negative binomial regression generated adjusted incidence rate ratios (aIRR) and 95% confidence intervals (CI). We evaluated lymphoma overall and by subtype: Hodgkin (HL; n = 1248), Non-Hodgkin excluding Burkitt (non-BL NHL; n = 658), Burkitt (BL; n = 241), and Diffuse Large B-cell (DLBCL; n = 315). There was no evidence that residential radon exposure was positively associated with lymphoma overall, HL, or BL. Areas with radon concentrations >75th percentile had a marginal increase in DLBCL incidence (aIRR = 1.73, 95% CI: 1.03–2.91). In one of the largest studies of residential radon exposure and the incidence of childhood lymphoma, we found little evidence to suggest a positive or negative association; an observation consistent with previous studies. PMID:26404336

  17. Residential Radon Exposure and Incidence of Childhood Lymphoma in Texas, 1995-2011.

    PubMed

    Peckham, Erin C; Scheurer, Michael E; Danysh, Heather E; Lubega, Joseph; Langlois, Peter H; Lupo, Philip J

    2015-10-01

    There is warranted interest in assessing the association between residential radon exposure and the risk of childhood cancer. We sought to evaluate the association between residential radon exposure and the incidence of childhood lymphoma in Texas. The Texas Cancer Registry (n = 2147) provided case information for the period 1995-2011. Denominator data were obtained from the United States Census. Regional arithmetic mean radon concentrations were obtained from the Texas Indoor Radon Survey and linked to residence at diagnosis. Exposure was assessed categorically: ≤25th percentile (reference), >25th to ≤50th percentile, >50th to ≤75th percentile, and >75th percentile. Negative binomial regression generated adjusted incidence rate ratios (aIRR) and 95% confidence intervals (CI). We evaluated lymphoma overall and by subtype: Hodgkin (HL; n = 1248), Non-Hodgkin excluding Burkitt (non-BL NHL; n = 658), Burkitt (BL; n = 241), and Diffuse Large B-cell (DLBCL; n = 315). There was no evidence that residential radon exposure was positively associated with lymphoma overall, HL, or BL. Areas with radon concentrations >75th percentile had a marginal increase in DLBCL incidence (aIRR = 1.73, 95% CI: 1.03-2.91). In one of the largest studies of residential radon exposure and the incidence of childhood lymphoma, we found little evidence to suggest a positive or negative association; an observation consistent with previous studies. PMID:26404336

  18. Let's Make the Next Generation Tobacco-Free: Your Guide to the 50th Anniversary Surgeon General's Report on Smoking and ...

    MedlinePlus

    ... or blocked arteries in and around the heart (coronary heart disease), high blood pressure (hypertension), heart attack (acute myocardial ... die every year in the United States from coronary heart disease caused by exposure to secondhand smoke. Peripheral Ar ...

  19. Symposium on the 50th anniversary of the discovery of deuterium: divisions of history of chemistry, geochemistry, nuclear and physical chemistry

    SciTech Connect

    Bigeleisen, J.

    1981-01-01

    In tribute to Harold Urey, the author cites Urey's accomplishments as a scientist and public servant and gives insight of the man. Some of his accomplishments in science are: discovered deuterium for which he received the Nobel prize in 1934; worked with Rittenberg and Greiff on the theory and calculation of the differences in the thermodynamic properties of isotopic compounds; with Thode, Hutchison and others, separated the isotopes of the light elements by chemical methods on a laboratory scale; during World War II headed the Substitute Alloy Materials Laboratories of Columbia University where his group developed industrial scale processes for the separation of /sup 2/H, /sup 10/B, and /sup 235/U; with his associates developed the /sup 18/O paleotemperature scale; made fundamental contributions to a widely accepted theory of the origin of the earth. (ATT)

  20. Milk and dairy products in the 21st century. Prepared for the 50th anniversary of the journal of agricultural and food chemistry.

    PubMed

    Creamer, Lawrence K; Pearce, Lindsay E; Hill, Jeremy P; Boland, Mike J

    2002-12-01

    Dairying into the 21st century will largely continue with the trends seen in the past few decades, although there is always the possibility of an unlikely but disruptive event. The politics of globalization will potentially be important in freeing up global trade in dairy products. Production on the farm will become increasingly efficient, resulting in continuing price benefits to the consumer. At the same time, increasing attention will be paid by the consumer, producer, and manufacturer to safety and quality issues. Environmental concerns will increase in importance, and the issue of methane production may be important for the industry over the next two decades. It is unlikely that genetically modified milk will be introduced soon, even if public acceptance ceases to be an issue; however, the use of genetic markers for accelerated genetic improvement of cows will have rapidly increasing importance. Despite increasing pressure from nonmilk alternatives, milk and dairy will still be the best sources of nutrition for the young and for traditional dairy products. Consumer concerns will be of overriding importance for the industry, and the safety of dairy foods must become absolute. Recent advances in the chemical, physical, and information sciences and technologies will be utilized to gain greater understanding of the increasingly complex food systems and to support the consumer objectives. PMID:12452630

  1. A resolution recognizing the 50th anniversary of the Congressional declaration of bourbon whiskey as a distinctive product of the United States.

    THOMAS, 113th Congress

    Sen. McConnell, Mitch [R-KY

    2014-05-15

    05/15/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S3049-3050; text as passed Senate: CR S3078) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  2. A resolution commemorating the 50th anniversary of the founding of the Organization of African Unity (OAU) and commending its successor, the African Union.

    THOMAS, 113th Congress

    Sen. Coons, Christopher A. [D-DE

    2013-06-10

    06/26/2013 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (consideration: CR S5304-5305) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  3. Commemorating the 50th anniversary of the founding of the Organization of African Unity (OAU) and commending its successor, the African Union.

    THOMAS, 113th Congress

    Rep. Bass, Karen [D-CA-37

    2013-05-23

    06/07/2013 Referred to the Subcommittee on Africa, Global Health, Global Human Rights and International Organizations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. Vacation Study Abroad 2000/2001: 50th Anniversary Edition of IIE's Complete Guide to Summer and Short-Term Study.

    ERIC Educational Resources Information Center

    Steen, Sara J., Ed.

    This guide provides descriptions of 2,239 summer and short-term study-abroad opportunities that range in length from one week to several months. Introductory material provides information on the Institute of International Education (IIE), IIE publications, how to use the guide, abbreviations, planning for study abroad, additional resources for…

  5. A resolution commemorating the 50th anniversary of the Bay of Pigs operation and commending the members of Brigada de Asalto 2506 (Assault Brigade 2506).

    THOMAS, 112th Congress

    Sen. Rubio, Marco [R-FL

    2011-04-12

    04/12/2011 Referred to the Committee on Foreign Relations. (text of measure as introduced: CR S2398) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. Comments on the Classic Henry and Rogers (1960) Paper on Its 50th Anniversary: Resolving the Issue of Simple versus Choice Reaction Time

    ERIC Educational Resources Information Center

    Klapp, Stuart T.

    2010-01-01

    The effect of response complexity on simple RT, first reported by Henry and Rogers (H&R), is a robust phenomenon for complexity measured by the number of chunks in a multiple-chunk response. However, there are problems with the memory drum theory H&R used to account for this result, and no fully satisfactory alternative explanation has been…

  7. S.Res.614 — 111th Congress (2009-2010) A resolution commemorating the 50th anniversary of the publication of "To Kill a Mockingbird".

    THOMAS, 111th Congress

    Sen. Sessions, Jeff [R-AL

    2010-08-05

    08/05/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6981; text as passed Senate: CR S6981; text of measure as introduced: CR S6908) (All Actions)

  8. [Polish School of Medicine at the University of Edinburgh, in the years of World War II. (50th anniversary of closure)].

    PubMed

    Imieliński, B L

    1999-01-01

    Half a century ago the activity of the Polish School of Medicine at the University of Edinburgh came to an end. It seems a good occasion to recall its beginnings and recognise its merits for Poland and for medical education. The school was a Scottish-Polish academic enterprise, unique in the history of universities, presenting an example of international academic co-operation. It was then the only legal Polish medical school in the years of World War II. The founders of it were: Lt.Col. Professor Francis A. E. Crew, Commanding Officer of the Military Hospital at Edinburgh Castle, who conceived the idea of a Polish medical school as a part of the University of Edinburgh, the Dean of the Medical Faculty, Professor Sidney Smith, who along with Sir Thomas Holland, the Principal of the University put the idea into motion through the University authorities on the Scottish side-and the Commander in Chief of the Polish Forces and Prime Minister General Władysław Sikorski, who gave his whole-hearted support and Lt.Col. Dr Antoni Jurasz, Professor of Surgery at the University of Poznań, who became the main organiser and first dean of the Faculty-on the Polish side. It was an independent Polish academic institution being simultaneously an integral part of the University. The medical training underwent 337 undergraduates, 227 out of whom obtained the degree M.B.Ch.B. and 19 degrees of Ph.D. after submission of doctoral thesis. The majority of them had served in the Polish troops being referred by the Military authorities and many of them took later part in the war campaigns. Much emphasis is put on the activity of Wiktor Tomaszewski, Associate Professor of medicine, ex-Senior Lecturer of the School, explorer of historical bounds between two nations, and above all, the organiser of the anniversary celebrations, so much animated by a passion for unceasing memory of the school. He was honored by granting F.R.C.P. (Ed.) and honorary doctorship of the University. PMID:14631981

  9. A resolution recognizing the 50th anniversary of the historic achievement of John Herschel Glenn, Jr., in becoming the first United States astronaut to orbit the Earth.

    THOMAS, 112th Congress

    Sen. Brown, Sherrod [D-OH

    2012-02-15

    02/15/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S690-692; text as passed Senate: CR S690-691; text of measure as introduced: CR S703-704) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  10. A resolution to observe the contributions of the American Chiropractic Association and to recognize the 50th anniversary of the founding of the organization.

    THOMAS, 113th Congress

    Sen. Harkin, Tom [D-IA

    2013-03-07

    03/07/2013 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S1274; text as passed Senate: CR S1273) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  11. Some results of the growth of semiconductor crystals in microgravity conditions (to the 50th anniversary of Yuri Gagarin's flight into space)

    NASA Astrophysics Data System (ADS)

    Shul'pina, I. L.; Zakharov, B. G.; Parfen'ev, R. V.; Farbshtein, I. I.; Serebryakov, Yu. A.; Prokhorov, I. A.

    2012-07-01

    The history of the growth of semiconductor crystals aboard space vehicles and their subsequent investigation has been described shortly. It has been shown using Ge(Ga), GaSb(Si), and GaSb(Te) crystals as an example that the formation of segregation growth striations can be avoided during their recrystallization by the vertical Bridgman method in conditions of physical simulation of microgravity on the Earth, mainly due to the essential weakening of the thermal gravitation convection. By their structure and impurity distribution, they approach the crystals grown in space. The investigation of recrystallization of Te has made it possible to determine the role of the detachment effect characteristic of the microgravity conditions and the features of the microstructure of the samples that crystallize with a free surface. The analysis of the results obtained from experiments in space allows us to better understand the processes occurring during the crystallization of the melts and to improve the crystal growth in terrestrial conditions.

  12. SHAPING the Future: Our Cause, 50 Million Strong. National Association of Kinesiology in Higher Education 50th Amy Morris Homans Commemorative Lecture 2016

    ERIC Educational Resources Information Center

    Lambdin, Dolly

    2016-01-01

    Amy Morris Homans was an amazing leader in the early development of physical education. She believed that every individual must be educated academically and physically. Earlier this year, SHAPE America committed to making her vision a reality with the goal of empowering ALL students with the skills, knowledge, habits, and determination to make…

  13. Value of MR histogram analyses for prediction of microvascular invasion of hepatocellular carcinoma

    PubMed Central

    Huang, Ya-Qin; Liang, He-Yue; Yang, Zhao-Xia; Ding, Ying; Zeng, Meng-Su; Rao, Sheng-Xiang

    2016-01-01

    Abstract The objective is to explore the value of preoperative magnetic resonance (MR) histogram analyses in predicting microvascular invasion (MVI) of hepatocellular carcinoma (HCC). Fifty-one patients with histologically confirmed HCC who underwent diffusion-weighted and contrast-enhanced MR imaging were included. Histogram analyses were performed and mean, variance, skewness, kurtosis, 1th, 10th, 50th, 90th, and 99th percentiles were derived. Quantitative histogram parameters were compared between HCCs with and without MVI. Receiver operating characteristics (ROC) analyses were generated to compare the diagnostic performance of tumor size, histogram analyses of apparent diffusion coefficient (ADC) maps, and MR enhancement. The mean, 1th, 10th, and 50th percentiles of ADC maps, and the mean, variance. 1th, 10th, 50th, 90th, and 99th percentiles of the portal venous phase (PVP) images were significantly different between the groups with and without MVI (P <0.05), with area under the ROC curves (AUCs) of 0.66 to 0.74 for ADC and 0.76 to 0.88 for PVP. The largest AUC of PVP (1th percentile) showed significantly higher accuracy compared with that of arterial phase (AP) or tumor size (P <0.001). MR histogram analyses—in particular for 1th percentile for PVP images—held promise for prediction of MVI of HCC. PMID:27368028

  14. Endogenous DNA Damage and Risk of Testicular Germ Cell Tumors

    SciTech Connect

    Cook, M B; Sigurdson, A J; Jones, I M; Thomas, C B; Graubard, B I; Korde, L; Greene, M H; McGlynn, K A

    2008-01-18

    Testicular germ cell tumors (TGCT) are comprised of two histologic groups, seminomas and nonseminomas. We postulated that the possible divergent pathogeneses of these histologies may be partially explained by variable endogenous DNA damage. To assess our hypothesis, we conducted a case-case analysis of seminomas and nonseminomas using the alkaline comet assay to quantify single-strand DNA breaks and alkali-labile sites. The Familial Testicular Cancer study and the U.S. Radiologic Technologists cohort provided 112 TGCT cases (51 seminomas & 61 nonseminomas). A lymphoblastoid cell line was cultured for each patient and the alkaline comet assay was used to determine four parameters: tail DNA, tail length, comet distributed moment (CDM) and Olive tail moment (OTM). Odds ratios (OR) and 95% confidence intervals (95%CI) were estimated using logistic regression. Values for tail length, tail DNA, CDM and OTM were modeled as categorical variables using the 50th and 75th percentiles of the seminoma group. Tail DNA was significantly associated with nonseminoma compared to seminoma (OR{sub 50th percentile} = 3.31, 95%CI: 1.00, 10.98; OR{sub 75th percentile} = 3.71, 95%CI: 1.04, 13.20; p for trend=0.039). OTM exhibited similar, albeit statistically non-significant, risk estimates (OR{sub 50th percentile} = 2.27, 95%CI: 0.75, 6.87; OR{sub 75th percentile} = 2.40, 95%CI: 0.75, 7.71; p for trend=0.12) whereas tail length and CDM showed no association. In conclusion, the results for tail DNA and OTM indicate that endogenous DNA damage levels are higher in patients who develop nonseminoma compared with seminoma. This may partly explain the more aggressive biology and younger age-of-onset of this histologic subgroup compared with the relatively less aggressive, later-onset seminoma.

  15. Photo series for quantifying fuels and assessing fire risk in giant sequoia groves. Forest Service general technical report

    SciTech Connect

    Weise, D.R.; Gelobter, A.; Haase, S.M.; Sackett, S.S.

    1997-03-01

    Fuels and stand inventory data are presented for giant sequoia by using 18 different photos located in giant sequoia/mixed conifer stands in the Sierra Nevada of California. Total fuel loading ranges from 7 to 72 tons/acre. The stands have been subjected to a variety of disturbances including timbers harvesting, wildfire, prescribed fire, and recreational use. Fire behavior predictions were made by using 10th, 50th, and 90th percentile weather conditions and the inventoried fuels information. The long-term visual impacts of the various management activities can also be partially assessed with this photo series.

  16. Haemoglobin recovery among HIV-1 infected patients on zidovudine-based antiretroviral therapy and other regimens in north-central Nigeria.

    PubMed

    Parrish, Deidra D; Blevins, Meridith; Megazzini, Karen M; Shepherd, Bryan E; Mohammed, Mukhtar Y; Wester, C William; Vermund, Sten H; Aliyu, Muktar H

    2014-04-01

    We conducted a study to assess trends in haemoglobin recovery among HIV-infected patients initiated on zidovudine-based combination antiretroviral therapy (cART) stratified by baseline haemoglobin level. Haemoglobin data from non-pregnant adult patients initiating cART in rural north-central Nigeria between June 2009 and May 2011 were analysed using a linear mixed effects model to assess the interaction between time, zidovudine-containing regimen and baseline haemoglobin level on the outcome of subsequent haemoglobin level. Best-fit curves were created for baseline haemoglobin in the 10th, 25th, 75th and 90th percentiles. We included 313 patients with 736 measures of haemoglobin in the analysis (239 on zidovudine and 74 on non-zidovudine-containing regimens). Median haemoglobin increased over time in both groups, with differences in haemoglobin response over time related to baseline haemoglobin levels and zidovudine use (p = 0.003). The groups of patients on zidovudine at the 10th and 90th percentiles had downward sloping curves while all other groups had upward trending haemoglobin levels. Although haemoglobin levels increased overall for patients on zidovudine-containing regimens, for those in the 10th and 90th percentiles haemoglobin levels trended downward over time. These results have implications for decisions regarding when to initiate, switch from or avoid the use of zidovudine. PMID:24104694

  17. Superposed epoch analysis and storm statistics from 25 years of the global geomagnetic disturbance index, USGS-Dst

    USGS Publications Warehouse

    Gannon, J.L.

    2012-01-01

    Statistics on geomagnetic storms with minima below -50 nanoTesla are compiled using a 25-year span of the 1-minute resolution disturbance index, U.S. Geological Survey Dst. A sudden commencement, main phase minimum, and time between the two has a magnitude of 35 nanoTesla, -100 nanoTesla, and 12 hours, respectively, at the 50th percentile level. The cumulative distribution functions for each of these features are presented. Correlation between sudden commencement magnitude and main phase magnitude is shown to be low. Small, medium, and large storm templates at the 33rd, 50th, and 90th percentile are presented and compared to real examples. In addition, the relative occurrence of rates of change in Dst are presented.

  18. [The 75th anniversary of science research and development testing centre of air medicine and military ergonomics SSRDTI of military medicine of Ministry of Defense of the RF].

    PubMed

    Bukhtiiarov, I V; Khomenko, M N; Zhdan'ko, I M

    2010-01-01

    The article presents main stages of forming Science research and development testing centre of air medicine and military ergonomics, results of researches of three main directions: medical-technical (ergonomic) supply of creation, testing and exploitation of air techniques and armament; participating in organization of combat training activity for the purposes of saving professional health, securing of combativity and professional reliability of aircraft pilots; scientific grounding of improvement of medical supply of aviation (improvement of medical control for dynamics of state of health, physiological and psychological resources of organism in course of combat training, creation of automatized diagnostic complexes and etc.). PMID:20536040

  19. S.Res.224 — 112th Congress (2011-2012) A resolution congratulating the Soil Science Society of America on its 75th anniversary.

    THOMAS, 112th Congress

    Sen. Moran, Jerry [R-KS

    2011-06-30

    06/30/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S4304-4305; text as passed Senate: CR S4304-4305; text of measure as introduced: CR S4298) (All Actions)

  20. S.Res.260 — 112th Congress (2011-2012) A resolution commemorating the 75th anniversary of the dedication of Shenandoah National Park.

    THOMAS, 112th Congress

    Sen. Webb, Jim [D-VA

    2011-09-08

    09/08/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR: S5465; text as passed Senate: CR S5465; text of measure as introduced: CR S5463) (All Actions)

  1. S.Res.545 — 112th Congress (2011-2012) A resolution commemorating the 75th Anniversary of Air Force Weather.

    THOMAS, 112th Congress

    Sen. Johanns, Mike [R-NE

    2012-08-02

    08/02/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S6012-6013; text as passed Senate: CR S6012; text of measure as introduced: CR S5992) (All Actions)

  2. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XIII: Magazines.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Magazine section of these proceedings contains the following six papers: "An Analysis of 'Magazine Type': Toward an Empirically Based Typology of Magazines and Non-Newspaper Periodicals" (Marcia R. Prior-Miller); "'Redbook': Changes in Attitude and Advice 1965-1990" (Jennifer Harbour); "A Quantitative Analysis of U.S. Consumer Magazines:…

  3. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XI: Advertising.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Advertising section of the proceedings contains the following 16 papers: "Ethics of Advertising Practitioners: An Explanation Based on a Classical Theoretical Framework" (Cornelius B. Pratt and E. Lincoln James); "Sex Roles in Frightening Film Newspaper Advertisements: An Overview of the Past 50 Years" (Melissa M. Spirek); "Is Seeing Believing…

  4. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). More Miscellaneous Studies.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The More Miscellaneous Studies section of the proceedings contains the following 34 papers: "The Louisville Courier-Journal's News Content after Purchase by Gannett" (Hansen and Coulson); "Reflection of Cultural Values in Advertising: A Comparative Analysis of Taiwan and U.S. Advertising" (Zandpour and Qian); "Sex, Violence and…

  5. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XIV: Newspapers.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Newspapers section of the proceedings contains the following 11 papers: "News Items in the 'Shrinking Foreign Newshole': The Case of the New York Times" (Daniel Riffe and others); "Newspaper Coverage of Gays and Lesbians: Editors' Views of Its Longterm Effects" (Marilyn Greenwald and Joseph Bernt); "Effects of Staff Gender on Newspaper…

  6. [Compromising conscientiously with reality but not with conscience. Reflections on the occasion of 75th anniversary of A. Stampar School of Public Health].

    PubMed

    Jaksić, Zelimir

    2002-09-01

    Changes in the activities and working conditions of the A. Stampar School of Public Health are reviewed following their anniversaries in the 25-year intervals. The differences have been described in understanding of major fields of work between: (1) social medicine (people's health) and public health; (2) health education following philosophy of Enlightenment and learning in the information era; (3) formal administrative organisation stressing implementation of given laws and entrepreneurial management in a society in transition; and (4) transfer of technology through international collaboration and under pressure of market oriented globalisation. Two basic points of view are identified: a social concern as opposite to technology-oriented productivity. It is concluded that a compromise of intentions and reality was always present looking for a balance between the described points of view. In relation to the present and future activities, the necessary compromise has to be conscientious, following the idea of preventive and social orientation applied to actual living problems of people and health care, namely people's health. PMID:19705565

  7. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part VII: Television.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Television section of the proceedings contains the following 10 papers: "Financial Commitment and Performance in Local Television News: Applying the Industrial Organizational Model" (Angela Powers); "The Relationship between Censorship and the Emotional and Critical Tone of Television News Coverage of the Persian Gulf War" (John E. Newhagen);…

  8. Facts all come with a point of view: some reflections on fact and formulation from the 75th anniversary edition of the International Journal of Psycho-Analysis.

    PubMed

    Cooper, S H

    1996-04-01

    In this paper the author examines some of the varieties of definitions of fact and formulation within contemporary psychoanalytic perspectives. A common thread running throughout various definitions of fact is the way in which fact is never theory-free. An attempt is made to compare and contrast the ways in which fact and formulation are contextually bound to theory. Questions are raised about the extent to which we can claim evidential status of propositions versus viewing formulations as useful illustrations of our work. Implicit in this paper is the current tension in psychoanalytic theory between psychoanalysis as a theory of motivation and meaning. PMID:8771377

  9. High lifetime and reproductive performance of sows on southern European Union commercial farms can be predicted by high numbers of pigs born alive in parity one.

    PubMed

    Iida, R; Piñeiro, C; Koketsu, Y

    2015-05-01

    Our objectives were 1) to compare reproductive performance across parity and lifetime performance in sow groups categorized by the number of pigs born alive (PBA) in parity 1 and 2) to examine the factors associated with more PBA in parity 1. We analyzed 476,816 parity records and 109,373 lifetime records of sows entered into 125 herds from 2008 to 2010. Sows were categorized into 4 groups based on the 10th, 50th, and 90th percentiles of PBA in parity 1 as follows: 7 pigs or fewer, 8 to 11 pigs, 12 to 14 pigs, and 15 pigs or more. Generalized linear models were applied to the data. For reproductive performance across parity, sows that had 15 or more PBA in parity 1 had 0.5 to 1.8 more PBA in any subsequent parity than the other 3 PBA groups ( P< 0.05). In addition, they had 2.8 to 5.4% higher farrowing rates in parities 1 through 3 than sows that had 7 or fewer PBA (P < 0.05). However, there were no differences between the sow PBA groups for weaning-to-first-mating interval in any parity (P ≥ 0.37). For lifetime performance, sows that had 15 or more PBA in parity 1 had 4.4 to 26.1 more lifetime PBA than sows that had 14 or fewer PBA (P < 0.05). Also, for sows that had 14 or fewer PBA in parity 1, those that were first mated at 229 d old (25th percentile) or earlier had 2.9 to 3.3 more lifetime PBA than those first mated at 278 d old (75th percentile) or later (P < 0.05). Factors associated with fewer PBA in parity 1 were summer mating and lower age of gilts at first mating (AFM; P < 0.05) but not reservice occurrences (P = 0.34). Additionally, there was a 2-way interaction between mated month groups and AFM for PBA in parity 1 (P < 0.05); PBA in parity 1 sows mated from July to December increased nonlinearly by 0.3 to 0.4 pigs when AFM increased from 200 to 310 d old (P < 0.05). However, the same rise in AFM had no significant effect on the PBA of sows mated between January and June (P ≥ 0.17). In conclusion, high PBA in parity 1 can be used to predict that a

  10. Pedogeochemical mapping of Al, Ba, Pb, Ti and V in soils of the Barcelona Province (Catalonia, NE Spain): relationships with soil physico-chemical properties.

    NASA Astrophysics Data System (ADS)

    Bech, J.; Reverter, F.; Tume, P.; Sokolowska, M.; Sanchez, P.; Longan, L.; Bech, J.; Zhiyanski, M.; Lansac, A.; Oliver, M. T.

    2009-04-01

    Pedogeochemical mapping is a useful tool for estimating the local background of potentially toxic elements (PTE), wich is essential for environmental regulation. The aim of this study is to estimate the levels and distribution of Al, Ba, Pb, Ti and V in surface soils of the Barcelona province (Catalonia, NE Spain) and their relationships with administrative-geographic districts, texture, pH, organic carbon and CaCO3. The studied region has a surface area of 7731 Km2. The geology is varied: granites and Paleozoic shales predominate in SE-E. and Mesozoic and Cenozoic limestones, dolomites, marlstones, gypsum and sandstones in the remainder of the studied area. 319 top soil samples (0-20 cm) were collected at 5 km intervals on a regular grid, dried and sieved (2mm). General soil properties were analysed by standard methods. Aqua regia digests (DIN 38414-S7) of Al, Ba, Pb, Ti and V were determined by Inductively Coupled Plasma Spectrometry. Statistical data treatment was carried out using SPSS 12.0 and Statgraphics Plus 5.1. We applied Exploratory Data Analysis (EDA) techniques to statistically describe the data. The software used for mapping was ESRI's Arc Wiew 9.0, Desktop version. Analytical data is represented using growing dot maps. The values of every mapped variable were grouped into a few cartographic classes in order to produce limited legends. The limits for the cartographic classes were chosen by the percentile method (5th, 25th, 50th, 75th, 90th, and 98th). Some results are: Al mg kg-1min 4410.0, max 194786.0, mean 18145.6, sd 12112.1, med 16273.3 ; Ba mgkg-1min 7.32, max 1709.0, mean 128.4, sd 149.2, med 91.7; Pb mg kg-1min 2.76, max 485.7, mean 52.2, sd 46.3, med 46.0; Ti mg kg-1min 11.6, max 3540.0, mean 268.0, sd 421.6, med 132.2, and V mg kg-1min 2.15, max 289.2, mean 31.4, sd 25.7, med 26.0. . The highest mean value of Ba (328mkg-1), Pb (139.6 mgkg-1) and V (54.7 mgkg-1) corresponds to the Barcelonés district with mainly urban soils. The Al contents

  11. Trigeminal Electrophysiology: a 2 × 2 matrix model for differential diagnosis between temporomandibular disorders and orofacial pain

    PubMed Central

    2010-01-01

    Background Pain due to temporomandibular disorders (TMDs) often has the same clinical symptoms and signs as other types of orofacial pain (OP). The possible presence of serious neurological and/or systemic organic pathologies makes differential diagnosis difficult, especially in early disease stages. In the present study, we performed a qualitative and quantitative electrophysiological evaluation of the neuromuscular responses of the trigeminal nervous system. Using the jaw jerk reflex (JJ) and the motor evoked potentials of the trigeminal roots (bR-MEPs) tests, we investigated the functional and organic responses of healthy subjects (control group) and patients with TMD symptoms (TMD group). Method Thirty-three patients with temporomandibular disorder (TMD) symptoms and 36 control subjects underwent two electromyographic (EMG) tests: the jaw jerk reflex test and the motor evoked potentials of the trigeminal roots test using bilateral electrical transcranial stimulation. The mean, standard deviation, median, minimum, and maximum values were computed for the EMG absolute values. The ratio between the EMG values obtained on each side was always computed with the reference side as the numerator. For the TMD group, this side was identified as the painful side (pain side), while for the control group this was taken as the non-preferred masticatory side (non-preferred side). The 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were also calculated. Results Analysis of the ratios (expressed as percentages) between the values obtained on both sides revealed a high degree of symmetry in the bR-MEPs % in the control (0.93 ± 0.12%) and TMD (0.91 ± 0.22%) groups. This symmetry indicated organic integrity of the trigeminal root motor fibers and correct electrode arrangement. A degree of asymmetry of the jaw jerk's amplitude between sides (ipJJ%), when the mandible was kept in the intercuspal position, was found in the TMD group (0.24% ± 0.14%) with a statistically

  12. Use of Developmental Milestones in Pediatric Residency Training and Practice: Time to Rethink the Meaning of the Mean

    PubMed Central

    Sices, Laura

    2009-01-01

    Objective Pediatricians frequently report the use of developmental milestones in monitoring young children’s development, despite evidence that use of screening tools improves detection of developmental delays. Methods Core texts in the field of pediatrics and developmental-behavioral pediatrics were reviewed for content and presentation on child development. Most texts included and many focused on developmental milestones, many with an emphasis on 50th percentile milestone data. Problems and limitations in the use of 50th percentile milestones to monitor young children’s development and to identify children whose development is suspicious for delay, include questionable utility in clinical decision making and the potential to increase parental anxiety. Results The recommendation is made to reconsider a focus on 50th percentile milestone data in pediatric training and practice, in favor of measures that have better clinical utility and are more psychometrically sound. Conclusion A conceptual approach to the presentation of developmental milestones differentiates the use of the 10th, 50th, and 90th percentiles of age of achievement of skills, based on the clinical purpose of surveillance. PMID:17353732

  13. Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes.

    PubMed

    Patel, Kashyap A; Oram, Richard A; Flanagan, Sarah E; De Franco, Elisa; Colclough, Kevin; Shepherd, Maggie; Ellard, Sian; Weedon, Michael N; Hattersley, Andrew T

    2016-07-01

    Distinguishing patients with monogenic diabetes from those with type 1 diabetes (T1D) is important for correct diagnosis, treatment, and selection of patients for gene discovery studies. We assessed whether a T1D genetic risk score (T1D-GRS) generated from T1D-associated common genetic variants provides a novel way to discriminate monogenic diabetes from T1D. The T1D-GRS was highly discriminative of proven maturity-onset diabetes of young (MODY) (n = 805) and T1D (n = 1,963) (receiver operating characteristic area under the curve 0.87). A T1D-GRS of >0.280 (>50th T1D centile) was indicative of T1D (94% specificity, 50% sensitivity). We then analyzed the T1D-GRS of 242 white European patients with neonatal diabetes (NDM) who had been tested for all known NDM genes. Monogenic NDM was confirmed in 90, 59, and 8% of patients with GRS <5th T1D centile, 50-75th T1D centile, and >75th T1D centile, respectively. Applying a GRS 50th T1D centile cutoff in 48 NDM patients with no known genetic cause identified those most likely to have a novel monogenic etiology by highlighting patients with probable early-onset T1D (GRS >50th T1D centile) who were diagnosed later and had less syndromic presentation but additional autoimmune features compared with those with proven monogenic NDM. The T1D-GRS is a novel tool to improve the use of biomarkers in the discrimination of monogenic diabetes from T1D. PMID:27207547

  14. Type 1 Diabetes Genetic Risk Score: a novel tool to discriminate monogenic and type 1 diabetes

    PubMed Central

    Patel, K A; Oram, R A; Flanagan, S E; De Franco, E; Colclough, K; shepherd, M; Ellard, S

    2016-01-01

    Distinguishing patients with monogenic diabetes from Type 1 diabetes (T1D) is important for correct diagnosis, treatment and to select patients for gene discovery studies. We assessed whether a T1D genetic risk score (T1D-GRS) generated from T1D-associated common genetic variants provides a novel way to discriminate monogenic diabetes from T1D. The T1D-GRS was highly discriminative of proven MODY (n=805) and T1D (n=1963) (ROC-AUC=0.87). A T1D-GRS of >0.280 (>50th T1D centile) was indicative of T1D (94% specificity, 50% sensitivity). We then analyzed the T1D-GRS in 242 White-European patients with neonatal diabetes (NDM) who had been tested for all known neonatal diabetes genes. Monogenic NDM was confirmed in 90%, 59% and 8% in patients with GRS <5th T1D centile, 50-75th T1D centile and >75th T1D centile, respectively. Applying a GRS 50th T1D centile cut-off in 48 NDM patients with no known genetic cause, identified those most likely to have a novel monogenic etiology by highlighting patients with probable early-onset T1D (GRS >50th T1D centile) who were diagnosed later, had less syndromic presentation but had additional autoimmune features compared to proven monogenic NDM. The T1D-GRS is a novel tool to improve the use of biomarkers in the discrimination of monogenic diabetes from T1D. PMID:27207547

  15. Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday Applications of zeta functions and other spectral functions in mathematics and physics: a special issue in honour of Stuart Dowker's 75th birthday

    NASA Astrophysics Data System (ADS)

    Dowker, Fay; Elizalde, Emilio; Kirsten, Klaus

    2012-09-01

    John Stuart Dowker was born in Sheffield, Yorkshire, on 18 March 1937. His life, therefore, was very much influenced by the Second World War. This is evident as his father died on active service in 1945, after being called up in 1941. His grandfather also died shortly afterwards, so he did not know either of them very well. Nevertheless, it seems that he picked up a positive attitude towards natural sciences as both were technically minded. His mother later provided, often from borrowed money, all the necessary intellectual food in forms of chemistry sets, slide rules and other things that a boy needed to develop his interests. Stuart scored excellently in the 11-plus exam, which was used to decide the type of school a pupil should attend after primary school. Although Stuart was generally allowed to do what he wanted, his mother insisted that he chose King Edward VII Grammar School (KES), the top school in Sheffield at the time. KES allowed Stuart to fully develop his intellectual abilities, and after the S-level exam he received a prestigious state scholarship which allowed him to study at any university in the country. He picked Nottingham over other possibilities, mainly because of his interest in electronics and because of the relative proximity to his family. In Nottingham, where he stayed from 1955 to 1958, his research concentration turned out to be mostly solid state physics. But with time on his hands, Stuart raided the library and taught himself things like complex analysis and quantum mechanics, with de Broglie's La mécanique ondulatoire [1] as one of his favorites. Remarkably, this book already contains a discussion of quantization on curved configuration spaces, a setting so relevant in Stuart's later career. Stuart wanted to investigate quantum field theory for his doctoral thesis. So he wrote, among others, to Rudolph Peierls in Birmingham, and, after being interviewed by Peierls himself and J G Valatin, he received an offer of a PhD position. He went to Birmingham in 1958, where his supervisor was Leonardo Castillejo, best known from the Castillejo-Dalitz-Dyson-ambiguity see [2]. His thesis involved stripping theory, and on this topic he wrote his first ever publication [3]. Takeaways from that time were that sometimes one simply has to do what one is told, and even more importantly, sometimes one has to get on with a calculation and 'just roll through it'. It was also around that period that Stuart started to learn quantum field theory properly following the developments of Feynman. After his PhD, it was Peierls who helped him to find a position at the University of Pennsylvania in Philadelphia in 1961, which he accepted before he received an offer from CERN. In retrospect, this was probably fortunate as it is where he met his wife, Pwu Yih, to whom he has been married for nearly 50 years. Scientifically he remained somewhat isolated there and spent much of his time learning more about quantum field theory, for example by reading Bogoliubov and Shirkov [4]. His entry point for general relativity was Eddington's The Mathematical Theory of Relativity [5], which together with the works of Julian Schwinger and Bryce de Witt were the most influential ones at that time. A shift of focus to questions in quantum field theory in curved space time took place. After his stay in Philadelphia, in 1963, helped by connections between Abe Klein and Brian Flowers, he went to the University of Manchester, where he remains to this day. This period was only briefly interrupted by a sabbatical in 1978 to 1979 at Austin following an invitation by Bryce de Witt. Looking back, it seems there were two major driving forces or principles that determined much of Stuart's selection of research projects. One of them is the method of images, about which he says: '...it intrigued me that one problem (charge + plane) could be got from another (just charge) by geometrical reasoning plus uniqueness. Thomson's book [6] took this further. Chapter 5 is devoted to the image and inversion methods and I must have read this closely as there ar

  16. Relationships between sea-level pressure and sea-level height in the Camargue (French Mediterranean coast) by Vincent Moron and Albin Ullmann, pages 1531-1540, Volume 25, Issue 11, 2005

    NASA Astrophysics Data System (ADS)

    Moron, Vincent

    2006-06-01

    A statistical study of daily maximum sea-level height at one station (Grau de la Dent) in the Camargue (Rhône delta, French Mediterranean coast) and daily sea-level pressure (SLP) at 12 h UTC over the eastern North Atlantic is used to identify the meteorological conditions associated with sea-level variations in the Camargue for the winters 1974-1975 to 2000-2001. Mean SLP composites during and 5 days before major surge events (defined as those with a daily maximum sea-level height > 80 cm) suggest the dominant influence of storms, moving northwest to southeast across the North Atlantic and strengthening as they approach the Bay of Biscay. During such storms, strong onshore winds may persist for up to 4-5 days. These winds tend to strengthen from 3 days to 1 day before the surge events. The mean October-March correlation between daily maximum sea-level height in the Camargue and SLP averaged over the Bay of Biscay (10°W-0° , 40° -50°N) is strong (r = - 0.69). A methodology is developed for assessing the low frequency SLP variability impact on sea-level height in the Camargue. A cross-validated linear regression is used to hindcast the interannual and intraseasonal variability of the monthly 75th and 90th percentiles of the daily maximum sea-level height from the monthly mean SLP over the Bay of Biscay. The linear correlation between the cross-validated hindcast and observed time series is 0.83 (0.77) for the 75th (90th) percentile over the 1974-1975 to 2000-2001 period. The mean bias error, reflecting systematic errors in predicting the monthly percentiles, is close to zero.

  17. Relationship between sea-level pressure and sea-level height in the Camargue (French Mediterranean coast)

    NASA Astrophysics Data System (ADS)

    Moron, V.; Ullmann, A.

    2005-09-01

    A statistical study of daily maximum sea-level height at one station (Grau de la Dent) in the Camargue (Rhône delta, French Mediterranean coast) and daily sea-level pressure (SLP) at 12 h UTC over the eastern North Atlantic is used to identify the meteorological conditions associated with sea-level variations in the Camargue for the winters 1974-75 to 2000-01. Mean SLP composites during and 5 days before major surge events (defined as those with a daily maximum sea-level height >80 cm) suggest the dominant influence of storms, moving northwest to southeast across the North Atlantic and strengthening as they approach the Bay of Biscay. During such storms, strong onshore winds may persist for up to 4-5 days. These winds tend to strengthen from 3 days to 1 day before the surge events. The mean October-March correlation between daily maximum sea-level height in the Camargue and SLP averaged over the Bay of Biscay (10°W-0°, 40-50°N) is strong (r = 0.69). A methodology is developed for assessing the low-frequency SLP variability impact on sea-level height in the Camargue. A cross-validated linear regression is used to hindcast the interannual and intraseasonal variability of the monthly 75th and 90th percentiles of the daily maximum sea-level height from the monthly mean SLP over the Bay of Biscay. The linear correlation between the cross-validated hindcast and observed time series is 0.83 (0.77) for the 75th (90th) percentile on the 1974-75 to 2000-01 period. The mean bias error, reflecting systematic errors in predicting the monthly percentiles, is close to zero.

  18. Does Behavioral Style Influence Learning Strategy in Health Professions Students?

    PubMed

    Williamson, J W; Krumwiede, K H; Reed, JoyLynn; Farmer, Suzanne; Behrendt, William

    2015-01-01

    Proficiency in areas of task completion, information processing, and time management are important attributes for successful academic performance and can be assessed using the Learning Assessment Study Strategies Inventory (LASSI). The purpose of this study was to determine if there were differences in learning strategies across four behavioral profiles using the DISC style analysis (Dominance, Influence, Steadiness, Compliance). Graduate health professions students (n=247) were administered the DISC and LASSI to assess study strategy categories based on their natural DISC behavioral style. A one-way ANOVA was used to assess differences for 10 LASSI category scores across the four DISC profiles; scores were also compared with national percentile scores. The D and C profiles were above the 75th percentile for information processing, but below the 50th percentile for self-testing. The S profile had significantly lower scores (p<0.005) for information processing and was below the 50th percentile for anxiety (i.e., higher anxiety). The I profile was below the 50th percentile for time management and concentration to academic tasks. The data are in close agreement with recognized behaviors specific for each behavioral style and suggest that behavioral style should be considered an important factor in academic performance. PMID:26342613

  19. Significant associations between hemostatic/fibrinolytic systems and accumulation of cardiovascular risk factors in Japanese elementary schoolchildren.

    PubMed

    Lin, Lisheng; Horigome, Hitoshi; Kato, Yoshiaki; Kikuchi, Toshihiro; Nakahara, Satoko; Sumazaki, Ryo

    2015-01-01

    The aim of this study was to establish the reference values of hemostatic/fibrinolytic markers and investigate their relationship with physical constitution and cardiovascular risk factors in a normal schoolchildren population. This study comprised 148 healthy Japanese children aged 9-10 years (males 73; females 75). We performed laboratory tests including blood levels of leptin, high-sensitive C-reactive protein (hs-CRP), hemostatic and fibrinolytic markers [plasminogen activator inhibitor 1 (PAI-1), coagulation factor VII (FVII), coagulation factor X (FX), fibrinogen (Fbg), protein C, protein S], as well as common biochemical markers in the morning after an overnight fast. We investigated the mean, 10th, 50th and 90th percentile values of these markers. All parameters were compared between two groups, that is those with body mass index (BMI) 90th percentile or higher and BMI less than 90th percentile, and between subgroups based on the number of cardiovascular risk factors. Multiple-linear regression was used to assess associations between these hematological parameters and the components related to metabolic syndrome (MetS). Alanine aminotransferase (ALT), uric acid, leptin, hs-CRP, and all hemostatic/fibrinolytic markers (PAI-1, FVII, FX, Fbg, protein C, protein S) tested were significantly higher in the group with BMI 90th percentile or higher, and increased with accumulation of cardiovascular risk factors. Multiple-linear regression analysis showed that these values were associated with one or more components related to MetS. Reference values of hemostatic/fibrinolytic markers in Japanese schoolchildren were obtained. Many hemostatic/fibrinolytic markers showed significant association with BMI and accumulation of cardiovascular risk factors in normal Japanese schoolchildren. PMID:25185676

  20. Clinical association of baseline levels of conjugated dienes in low-density lipoprotein and nitric oxide with aggressive B-cell non-Hodgkin lymphoma and their relationship with immunoglobulins and Th1-to-Th2 ratio

    PubMed Central

    Haddouche, Mustapha; Meziane, Warda; Hadjidj, Zeyneb; Mesli, Naima; Aribi, Mourad

    2016-01-01

    Objective The aim of this study was to highlight the clinical association of baseline levels of conjugated dienes in low-density lipoprotein (LDL-BCD) and nitric oxide (NO) with immunoglobulins (Igs) and T helper (Th)1/Th2 ratio in patients with newly diagnosed B-cell non-Hodgkin lymphoma (NHL). Patients and methods Thirty-two newly diagnosed patients with aggressive B-cell NHL and 25 age-, sex-, and body-mass-index-matched healthy controls were randomly selected for a cross-sectional case–control study conducted at the Hematology Department of Tlemcen Medical Centre University (northwest of Algeria). Results Circulating levels of LDL-BCD and NO and those of IgA and IgM were significantly higher in patients than in controls. The levels of Th1/Th2 ratio and plasma total antioxidant capacity were significantly lower in patients compared with controls, while malondialdehyde and protein carbonyl levels were significantly higher in patients. B-cell NHL was significantly associated with high levels of LDL-BCD from 25th to 75th percentile (25th percentile: relative risk [RR] =2.26, 95% confidence interval [CI] 1.42–3.59, P=0.014; 50th percentile: RR =2.84, 95% CI 1.72–4.68, P<0.001; 75th percentile: RR =5.43, 95% CI 2.58–11.42, P<0.001). Similarly, the disease was significantly associated with high levels of NO production from 25th to 75th percentile (25th percentile: RR =2.07, 95% CI 1.25–3.44, P=0.024; 50th percentile: RR =2.78, 95% CI 1.63–4.72, P<0.001; 75th percentile: RR =4.68, 95% CI 2.21–9.91, P<0.001). Moreover, LDL-BCD levels were positively and significantly correlated with interferon (IFN)-γ, whereas NO levels were inversely and significantly correlated with IFN-γ and Th1/Th2 ratio. Conclusion LDL-BCD and NO production seem to be associated with aggressive B-cell NHL and alteration of Th1/Th2 ratio. Our results have to be examined using ex vivo mechanistic studies leading to further investigations of these parameters, with an interest in the

  1. Consistency of FMEA used in the validation of analytical procedures.

    PubMed

    Oldenhof, M T; van Leeuwen, J F; Nauta, M J; de Kaste, D; Odekerken-Rombouts, Y M C F; Vredenbregt, M J; Weda, M; Barends, D M

    2011-02-20

    In order to explore the consistency of the outcome of a Failure Mode and Effects Analysis (FMEA) in the validation of analytical procedures, an FMEA was carried out by two different teams. The two teams applied two separate FMEAs to a High Performance Liquid Chromatography-Diode Array Detection-Mass Spectrometry (HPLC-DAD-MS) analytical procedure used in the quality control of medicines. Each team was free to define their own ranking scales for the probability of severity (S), occurrence (O), and detection (D) of failure modes. We calculated Risk Priority Numbers (RPNs) and we identified the failure modes above the 90th percentile of RPN values as failure modes needing urgent corrective action; failure modes falling between the 75th and 90th percentile of RPN values were identified as failure modes needing necessary corrective action, respectively. Team 1 and Team 2 identified five and six failure modes needing urgent corrective action respectively, with two being commonly identified. Of the failure modes needing necessary corrective actions, about a third were commonly identified by both teams. These results show inconsistency in the outcome of the FMEA. To improve consistency, we recommend that FMEA is always carried out under the supervision of an experienced FMEA-facilitator and that the FMEA team has at least two members with competence in the analytical method to be validated. However, the FMEAs of both teams contained valuable information that was not identified by the other team, indicating that this inconsistency is not always a drawback. PMID:20970277

  2. A resolution recognizing the 50th anniversary of the ratification of the Treaty of Mutual Security and Cooperation with Japan, and affirming support for the United States-Japan security alliance and relationship.

    THOMAS, 111th Congress

    Sen. Webb, Jim [D-VA

    2010-06-23

    06/29/2010 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (consideration: CR S5630; text as passed Senate: CR S5630) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  3. S.Res.72 — 112th Congress (2011-2012) A resolution recognizing the artistic and cultural contributions of the Alvin Ailey American Dance Theater and the 50th Anniversary of the first performance of Alvin Ailey's masterwork, "Revelations".

    THOMAS, 112th Congress

    Sen. Gillibrand, Kirsten E. [D-NY

    2011-02-17

    02/17/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S924-926; text as passed Senate: CR S924; text of measure as introduced: CR S917-918) (All Actions)

  4. N-Phosphoryl Amino Acids and Biomolecular Origins. Review Paper in Honor of the 50th Anniversary of the Publication of ``A Production of Amino Acids under Possible Primitive Earth Conditions'' (Miller, 1953)

    NASA Astrophysics Data System (ADS)

    Cheng, C. M.; Liu, X. H.; Li, Y. M.; Ma, Y.; Tan, B.; Wan, R.; Zhao, Y. F.

    2004-10-01

    The possible role of phosphoryl amino acids for biomolecular origins is briefly reviewed. Peptide formation, ester formation, ester exchange on phosphorus and N to O migration occurred when the N-phosphoryl amino acid was incubated at room temperature. Short nucleotides and peptides were formed when nucleoside was reacted with N-phosphoryl amino acid at room temperature. Serine and threonine residues in their conjugate with different nucleosides (mediated with phosphorus) showed different self-cleavage activities. N-phosphoryl Histine and Ser-His dipeptide could cleave nucleic acids, proteins and esters in neutral medium. Based on a simple model, a pathway of `co-evolution of protein and nucleic acid' was proposed.

  5. S.Res.377 — 112th Congress (2011-2012) A resolution recognizing the 50th anniversary of the historic achievement of John Herschel Glenn, Jr., in becoming the first United States astronaut to orbit the Earth.

    THOMAS, 112th Congress

    Sen. Brown, Sherrod [D-OH

    2012-02-15

    02/15/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S690-692; text as passed Senate: CR S690-691; text of measure as introduced: CR S703-704) (All Actions)

  6. Celebration of the 50th anniversary of the foundation of the French society for connective tissue research. Its short history in the frame of the origin and development of this discipline.

    PubMed

    Borel, J P; Maquart, F X; Robert, A M; Labat-Robert, J; Robert, L

    2012-02-01

    The science of connective tissues has (at least) a double origin. Collagen, their major constituent was first studied in conjunction with the leather industry. Acid mucopolysaccharides (now glycosaminoglycans) were characterised by (bio)-chemists interested in glycoconjugates. They joined mainly hospital-based rheumatology departments. Later started the study of elastin with the discovery of elastases and of connective tissue-born (structural) glycoproteins. Besides rhumatologists and leather-chemists mainly pathologists became involved in this type of research, followed closely by ophthalmology research. The first important meetings of these diverse specialists were organised under the auspices of NATO, first in Saint-Andrew's in GB in 1964 and a few years later (1969) in Santa Margareta, Italy. With the discovery of fibronectin, a "structural glycoprotein", started the study of cell-matrix interactions, reinforced by the identification of cell-receptors mediating them and the "cross-talk" between cells and matrix constituents. The first initiative to organise societies for this rapidly growing discipline was that of Ward Pigman in New York in 1961, restricted however to glycol-conjugates. Next year, in 1962 was founded the first European Connective Tissue Society in Paris: the "Club français du tissu conjonctif", which played a crucial role in the establishment of schools, laboratories, national and international meetings in the major cities of France: Paris, Lyon, Reims, Caen,Toulouse. A second European society was born in Great Britain, and at a joint meeting with the French society at the Paris Pasteur Institute, was founded in 1967 by these societies the Federation of European Connective Tissue Societies (FECTS). Their meetings, organised every second year, drained a wide attendance from all over the world. An increasing number of young scientists joined since then this branch of biomedical discipline with several international journals devoted to connective tissue research, to matrix biology. The increasing number and quality of the young generation of scientists engaged in research related to the extracellular matrix or better Biomatrix and cell-matrix interactions is a further guarantee for the continued interest in this crucial field of science at the interface of basic and medically oriented research. PMID:22265965

  7. Continuing Higher Education: In Retrospect and toward the Future. Proceedings of the Annual Meeting, Association for Continuing Higher Education (50th, Salt Lake City, Utah, October 30-November 2, 1988).

    ERIC Educational Resources Information Center

    Jackson, Jan, Ed.

    These proceedings contain addresses and summaries of presentations made in concurrent sessions at the annual meeting. The addresses are: Association for Continuing Higher Education (ACHE)--Then and Now: What Our Past Has To Tell Us about Our Future" (Nelcamp and others); "A Conversation with Alex Haley" (Haley); "Luncheon Address of…

  8. S.Res.576 — 112th Congress (2011-2012) A resolution celebrating the 50th anniversary of the signing of Public Law 87-788, an Act commonly known as the McIntire-Stennis Cooperative Forestry Act.

    THOMAS, 112th Congress

    Sen. Cochran, Thad [R-MS

    2012-09-22

    09/22/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR 9/21/2012 S6679-6684; text as passed Senate: CR 9/21/2012 S6680; text of measure as introduced: CR 9/21/2012 S6630) (All Actions)

  9. DESIGN AND CONSTRUCTION OF SCHOOL BUILDINGS. PROCEEDINGS, ASSOCIATION OF SCHOOL BUSINESS OFFICIALS OF THE UNITED STATES AND CANADA, ANNUAL MEETING AND EDUCATIONAL EXHIBIT, (50TH SAN FRANCISCO, CALIFORNIA, OCTOBER 71-22, 1964).

    ERIC Educational Resources Information Center

    LIEBESKIND, MORRIS

    PROBLEMS IN THE SCHEDULING AND COMPLETION OF SCHOOL BUILDING DESIGN AND CONSTRUCTION PROJECTS ARE DISCUSSED WITH REFERENCE TO THE CRITICAL PATH METHOD OF PROGRAMING. THE DISCUSSION GIVES A BROAD OVERVIEW OF THE METHOD WITH DETAILED SUGGESTIONS FOR SCHOOL ADMINISTRATORS. SPECIFIC SUBJECT AREAS INCLUDE--(1) CPM, A NEW MANAGEMENT TOOL, (2) CPM…

  10. A resolution celebrating the 50th anniversary of the signing of Public Law 87-788, an Act commonly known as the McIntire-Stennis Cooperative Forestry Act.

    THOMAS, 112th Congress

    Sen. Cochran, Thad [R-MS

    2012-09-22

    09/22/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR 9/21/2012 S6679-6684; text as passed Senate: CR 9/21/2012 S6680; text of measure as introduced: CR 9/21/2012 S6630) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  11. Theodor Billroth's vision and Karl Ziegler's action: commemoration of the 40th day of death and the 50th anniversary of conferment of Nobel Prize for Chemistry of Karl Ziegler.

    PubMed

    Kapischke, Matthias; Pries, Alexandra

    2014-02-01

    Alloplastic materials are broadly used in modern surgery. Until the middle of the 20th century, metal materials and especially silver were used because of their antimicrobial properties. With the development of a new catalytic process for the production of high-density polyethylene and polypropylene materials, a new era of prosthesis was introduced. These polymers are integral part of our everyday operations surgery, especially in hernia repair. The famous surgeon Billroth mentioned to his pupil Czerny in 1878: "If we could artificially produce tissues of the density and toughness of fascia and tendon, the secret of the radical cure of hernia would be discovered". The polypropylene developed by Karl Ziegler gave the surgeon a material for daily practice, which in its properties (nearly) achieved Billroth's initial vision. In 1963 the Nobel Prize for Chemistry was awarded to Karl Ziegler and Giulio Natta in Stockholm. Furthermore, August 11, 2013 will be the 40th anniversary of Karl Ziegler's death. This manuscript honors both days. PMID:24387785

  12. News and Views: Extrasolar mineralogy; ESO's 50th birthday; VISTA views a vast ball of stars; First instrument ready for JWST; PCs can process Pan-STARRS1 images at home; JIVE goes to SA

    NASA Astrophysics Data System (ADS)

    2012-06-01

    After more than 10 years of work by more than 200 engineers, the Mid InfraRed Instrument (MIRI) is the first of four instruments to be completed for the James Webb Space Telescope, whose design and construction has been led by Britain in partnership with European institutions. Images from the Panoramic Survey Telescope & Rapid Response System (Pan-STARRS) will be processed using distributed computer time through theSkyNet, a “citizen science” programme developed for radio data by the International Centre for Radio Astronomy Research (ICRAR).

  13. Optimal Skin-to-Stone Distance Is a Positive Predictor for Successful Outcomes in Upper Ureter Calculi following Extracorporeal Shock Wave Lithotripsy: A Bayesian Model Averaging Approach

    PubMed Central

    Cho, Kang Su; Jung, Hae Do; Ham, Won Sik; Chung, Doo Yong; Kang, Yong Jin; Jang, Won Sik; Kwon, Jong Kyou; Choi, Young Deuk; Lee, Joo Yong

    2015-01-01

    Objectives To investigate whether skin-to-stone distance (SSD), which remains controversial in patients with ureter stones, can be a predicting factor for one session success following extracorporeal shock wave lithotripsy (ESWL) in patients with upper ureter stones. Patients and Methods We retrospectively reviewed the medical records of 1,519 patients who underwent their first ESWL between January 2005 and December 2013. Among these patients, 492 had upper ureter stones that measured 4–20 mm and were eligible for our analyses. Maximal stone length, mean stone density (HU), and SSD were determined on pretreatment non-contrast computed tomography (NCCT). For subgroup analyses, patients were divided into four groups. Group 1 consisted of patients with SSD<25th percentile, group 2 consisted of patients with SSD in the 25th to 50th percentile, group 3 patients had SSD in the 50th to 75th percentile, and group 4 patients had SSD≥75th percentile. Results In analyses of group 2 patients versus others, there were no statistical differences in mean age, stone length and density. However, the one session success rate in group 2 was higher than other groups (77.9% vs. 67.0%; P = 0.032). The multivariate logistic regression model revealed that shorter stone length, lower stone density, and the group 2 SSD were positive predictors for successful outcomes in ESWL. Using the Bayesian model-averaging approach, longer stone length, lower stone density, and group 2 SSD can be also positive predictors for successful outcomes following ESWL. Conclusions Our data indicate that a group 2 SSD of approximately 10 cm is a positive predictor for success following ESWL. PMID:26659086

  14. Applicability of Two Universally Accepted Mixed Dentition Analysis on a Sample from Southeastern Region of Andhra Pradesh, India

    PubMed Central

    Shobha, MB; AJS, Sai; Manoj, KMG; Srideevi, E; Sridhar, M; Pratap, GMJS

    2016-01-01

    Background: Most of the universally accepted mixed dentition analyses are based on the data derived from northwestern European descent. However, the accuracy of these methods when applied to different ethnic population is questionable. Aim: The present study is aimed to evaluate the applicability of Tanaka and Johnston (TJ) and Moyers (50th and 75th percentile) mixed dentition analysis in a sample from south-eastern region of Andhra Pradesh, India. Subjects and Methods: Study models were prepared from a sample of 100 patients (50 males and 50 females) in the age range of 13-15 years. The mesio-distal dimension of the teeth was measured using a Digital Vernier calipers. The actual values of permanent canine and premolars on the casts were compared with the predicted values from TJ and Moyers analysis. The values derived from this study were statistically analyzed using SPSS version 17.0 (IBM, Chicago, USA). Pearson's coefficients were used to evaluate the correlations between the groups of teeth. Results: Overestimated values were noticed in males and females of both arches with TJ equation; Males showed no significant difference at Moyers 50th percentile (50/100), in both the arches where as females showed higher values in mandibular arch and underestimated values in maxillary arch. At Moyers 75th percentile, overestimated values were noticed in males for both the arches whereas in females lesser values were observed. Conclusion: As the values showed significant deviation from TJ and Moyers both at 50 and 75 percentile, its applicability to the present population is limited. So, new regression equations were derived. PMID:27398250

  15. Air Pollution and the Risk of Cardiac Defects: A Population-Based Case-Control Study.

    PubMed

    Hwang, Bing-Fang; Lee, Yungling Leo; Jaakkola, Jouni J K

    2015-11-01

    Previous epidemiologic studies have assessed the role of the exposure to ambient air pollution in the development of cardiac birth defects, but they have provided somewhat inconsistent results. To assess the associations between exposure to ambient air pollutants and the risk of cardiac defects, a population-based case-control study was conducted using 1087 cases of cardiac defects and a random sample of 10,870 controls from 1,533,748 Taiwanese newborns in 2001 to 2007.Logistic regression was performed to calculate odds ratios for 10 ppb increases in O3 and 10 μg/m increases in PM10. In addition, we compared the risk of cardiac defects in 4 categories-high exposure (>75th percentile); medium exposure (75th to 50th percentile); low exposure (<50th-25th percentile); reference (<25th percentile) based on the distribution of each pollutant. The risks of ventricular septal defects (VSD), atrial septal defects (ASD), and patent ductus arteriosus (PDA) were associated with 10 ppb increases in O3 exposure during the first 3 gestational months among term and preterm babies. In comparison between high PM10 exposure and reference category, there were statistically significant elevations in the effect estimates of ASD for all and terms births. In addition, there was a negative or weak association between SO2, NO2, CO, and cardiac defects.The study proved that exposure to outdoor air O3 and PM10 during the first trimester of gestation may increase the risk of VSD, ASD, and PDA. PMID:26554783

  16. Effect of Menopausal Status on Carotid Intima-Media Thickness and Presence of Carotid Plaque in Chinese Women Generation Population

    PubMed Central

    Zhou, Yong; Wang, Dandan; Yang, Xin; Wang, Anxin; Gao, Xiang; Guo, Yuming; Wu, Shouling; Zhao, Xingquan

    2015-01-01

    Menopause is an important physiological stage in women's life. The potential association of menopause with carotid intima-media thickness as well as with occurrence and stability of carotid plaque in Chinese female population is unclear. We conducted a population-based, cross-sectional study by recruiting 2,131 participants aged above 40 years from northeast of China. Carotid intima-media thickness (CIMT), presence of carotid plaque and its stability were evaluated by carotid duplex sonography. Among the participants, 1,133 (53.2%) were identified to be postmenopausal. After adjusting for potential confounding factors, presence of CIMT at 50th- 75th and ≥75th percentiles, carotid plaque and its unstable status were found to be significantly associated with the postmenopausal status (P < 0.001). When matched the participants by age, post-menopausal status was still associated with a higher risk of having unstable plaque. Moreover, our data show that postmenopausal status is a risk factor for intracranial arterial stenosis when compared with premenopausal status in the univariate analysis (OR = 1.314, P = 0.043), and such relationship is lost when the confounding factors are adjusted (OR = 0.828, P = 0.225). In conclusion, the vascular risk factors increase as the menopausal status changes. Compared with premenopausal status, postmenopausal status is associated with higher morbidity of CIMT, carotid plaque and its unstable status. PMID:25627797

  17. Comparison of methods for uncertainty analysis of nuclear-power-plant safety-system fault-tree models. [PWR; BWR

    SciTech Connect

    Martz, H F; Beckman, R J; Campbell, K; Whiteman, D E; Booker, J M

    1983-04-01

    A comparative evaluation is made of several methods for propagating uncertainties in actual coupled nuclear power plant safety system faults tree models. The methods considered are Monte Carlo simulation, the method of moments, a discrete distribution method, and a bootstrap method. The Monte Carlo method is found to be superior. The sensitivity of the system unavailability distribution to the choice of basic event unavailability distribution is also investigated. The system distribution is also investigated. The system distribution is especially sensitive to the choice of symmetric versus asymmetric basic event distributions. A quick-and dirty method for estimating percentiles of the system unavailability distribution is developed. The method identifies the appropriate basic event distribution percentiles that should be used in evaluating the Boolean system equivalent expression for a given fault tree model to arrive directly at the 5th, 10th, 50th, 90th, and 95th percentiles of the system unavailability distribution.

  18. Simulation of Electron-Beam Irradiation of Skin Tissue Model

    SciTech Connect

    Miller, John H.; Suleiman, Atef; Chrisler, William B.; Sowa, Marianne B.

    2011-01-03

    Monte Carlo simulation of electrons stopping in liquid water was used to model the penetration and dose distribution of electron beams incident on the full-thickness EpiDermTM skin model (MatTek, Ashland, VA). This 3D tissue model has a fully developed basement membrane separating an epidermal layer of keratinocytes in various stages of differentiation from a dermal layer of fibroblast embedded in collagen. The simulations were motivated by a desire to selectively expose the epidermal layer to low linear-energy-transfer (LET) radiation in the presence of a non-irradiated dermal layer. Using the variable energy electron microbeam at the Pacific Northwest National Laboratory (PNNL) as a model of device characteristics and irradiation geometry, we find that at the highest beam energy available (90 keV), the estimated 90th percentile of penetration remains in the epidermal layer. To investigate the depth-dose distribution, we calculated lineal energy spectra for 10um thick layers near the 10th, 50th, and 90th percentile of penetration by the 90 keV electron beam. Biphasic spectra showed an increasing component of "stoppers" with increasing depth. Despite changes in the lineal energy spectra, the main effect on dose deposition with increasing depth is the screening effect of tissue above the layer of interest.

  19. Anthropometric indices among schoolchildren from a municipality in Southern Brazil: a descriptive analysis using the LMS method☆

    PubMed Central

    Barbosa, Valter Cordeiro; Lopes, Adair da Silva; Fagundes, Ricardo Rosa; de Campos, Wagner

    2014-01-01

    OBJECTIVE: To describe the percentile values for body mass index (BMI), waist circumference (WC) and waist-to-height (WHtR) of children from Colombo, Brazil, and compare them with data of children from other countries. METHODS: This was a cross-sectional study with a random sample of 2,035 children aged 6-11 years. Age- and sex-specific smoothed percentiles curves for BMI, WC and WHtR were created using the LMS method. Values of 10th, 50th and 90th percentiles from Brazilian children were compared with data from other countries. RESULTS: There was a trend of increasing BMI and WC with age in both sexes. WHtR remained constant with advancing age in boys and girls. Comparison of the growth pattern among countries showed clear differences. Southern Brazil boys and girls had elevated 90th percentile values for BMI, which was similar to German children and higher than the North American and World Health Organization percentile values. However, children from this study had intermediate values for WC and WHtR in comparison to children from other countries. CONCLUSIONS: Elevated BMI values were observed among southern Brazilian children, but WC and WHtR percentile values were lower in southern Brazilian children than in children from other countries. Interventions at different levels should be made to avoid a probable increase of nutritional disorders (especially general obesity) in the next years. PMID:25510997

  20. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XVI: Miscellaneous Studies.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Miscellaneous Studies section of the proceedings contains the following 16 papers: "Mickey Mouse and Bugs Bunny: Iconography of Two Corporate Stars" (William A. Mikulak); "We Know Who You Are: A Niche Communications Explication and Model" (Jana Frederick-Collins); "The Ways They Get Their Stories: Is Utilitarianism the Best Moral Theory for…

  1. Assessment System for Special Education Students Exempted from the Texas Assessment Program. A Report Submitted to the Governor, Lieutenant Governor, Speaker of the House, and the 75th Texas Legislature.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin.

    The Texas Education Code requires the Commissioner of Education to develop and propose a system for evaluating the progress of students eligible for exemption from the statewide assessment program under current law. This report summarizes the proposed system for special education students. It includes proposed changes to the assessment and…

  2. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part II: Journalism History, Section B.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section B of the Journalism History section of the proceedings contains the following nine papers: "Weep into Silence/Cries of Rage: Bitter Divisions in Hawaii's Japanese Press" (Tom Brislin); "Viewing the Newspaper as International: The First International Organization of Journalists Debates News Copyright 1894-1898" (Ulf Jonas Bjork); "The…

  3. Political Science's Responsibility to the Community: A Promise Fulfilled? Anniversary Sessions of the Department of Political Science, University of Illinois (75th, Urbana-Champaign, Illinois, November 20-21, 1981). The Edmund James James Lecture.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Dept. of Political Science.

    This report contains the keynote speech, the panel discussions, and questions (with responses) from the audience for each of two major sessions on the responsibility of political science to the community. The focus of the first session was academic political science and public service. The keynote speaker was William N. Cassella. Panelists were…

  4. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part III: Media History.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Media History section of the proceedings contains the following nine papers: "'This Is a Test': The Evolution of the Emergency Broadcast System" (Larry G. Burkum); "Radio Homemaker Programming: Old Time Radio's Ingredient for Attracting Women Listeners" (J. Steven Smethers and Lee Jolliffe); "Her Amplified Voice: Gender, War Propaganda and…

  5. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part IX: Media and Technology.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Media and Technology section of these proceedings contains the following six papers: "The Effects of Tabular and Graphical Display Formats on Time Spent Processing Statistics" (James D. Kelly); "Program Choice in a Broadband Environment" (Steven S. Wildman and Nancy Y. Lee); "Visual Crosstabs: A Technique for Enriching Information Graphics"…

  6. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part I: Journalism History, Section A.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section A of the Journalism History section of the proceedings contains the following 10 papers: "Mixed Messages in a Progressive Newspaper: The Milwaukee Journal and Woman Suffrage, 1911-1912" (Elizabeth Burt); "The Search for Unity: The Importance of the Black Press in the Emigration/Colonization Issues of the 1800s" (Bernell E. Tripp);…

  7. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part IV: Media and Law, Section A.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section A of the Media and Law section of the proceedings contains the following nine papers: "RICO and the First Amendment: Racketeering Laws Threaten Free Expression" (Matthew D. Bunker and others); "Press Coverage of the Federal Appellate Courts: Technology and a Shared Notion of Newsworthiness" (Rebekah V. Bromley); "The Evolution of Illinois…

  8. A resolution recognizing the 75th anniversary of the founding of Ducks Unlimited, Incorporated, the achievements of the organization in habitat conservation, and the support of the organization for the waterfowling heritage of the United States.

    THOMAS, 112th Congress

    Sen. Wicker, Roger F. [R-MS

    2012-04-19

    04/19/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2557; text as passed Senate: CR S2557; text of measure as introduced: CR S2553) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  9. Investing in Human Capital. Leadership for the Challenges of the 21st Century. Edited Proceedings of the Institute of International Education Forum (75th, New York, New York, October 27, 1994).

    ERIC Educational Resources Information Center

    Institute of International Education, New York, NY.

    These proceedings highlight the Institute for International Education's forum on the implications of the emergence of a global economy and the worldwide communications revolutions for international education and training. Over 200 individuals from the corporate, foundation, government, academic, and diplomatic communities participated in the…

  10. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part VIII: Mass Media Effects.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Mass Media Effects section of the proceedings contains the following eight papers: "The Spiral of Static: A Multivariate Analysis of a Public Opinion Theory Applied to Perception of Radio Station Popularity" (Terry Wedel and Tony Rimmer); "More Than Just Talk: Uses, Gratifications and the Telephone" (Garrett J. O'Keefe and Barbara K.…

  11. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part X: Health, Science, and the Environment.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Health, Science, and the Environment section of these proceedings contains the following seven papers: "Columbus, Mars, and the Changing Images and Ideologies of Exploration: A Critical Examination" (Lin Bin and August T. Horvath); "Prime Time TV Portrayals of Sex, 'Safe Sex' and AIDS: A Longitudinal Analysis" (Dennis T. Lowry and Jon A.…

  12. S.Res.430 — 112th Congress (2011-2012) A resolution recognizing the 75th anniversary of the founding of Ducks Unlimited, Incorporated, the achievements of the organization in habitat conservation, and the support of the organization for...

    THOMAS, 112th Congress

    Sen. Wicker, Roger F. [R-MS

    2012-04-19

    04/19/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2557; text as passed Senate: CR S2557; text of measure as introduced: CR S2553) (All Actions)

  13. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part V: Media and Law, Section B.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    Section B of the Media and Law section of the proceedings contains the following nine papers: "The Professional Person as Libel Plaintiff: Reexamination of the Public Figure Doctrine" (Harry W. Stonecipher and Don Sneed); "The Anti-Federalists and Taxation under the Free Press Clause of the First Amendment" (Brad Thompson); "Independent State…

  14. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part XII: Foreign and International Media.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The International Media section of the proceedings contains the following 13 papers: "Text and Context: A Case Study of International News Discourse" (Shujen Wang); "The Future of Public Service Broadcasting in Japan and the U.K.: A Comparative Analysis" (Roya Akhavan-Majid); "Reinventing Freedom of the Press: The Search for a Post-Soviet Model in…

  15. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (75th, Montreal, Quebec, Canada, August 5-8, 1992). Part VI: Politics and Mass Media.

    ERIC Educational Resources Information Center

    Association for Education in Journalism and Mass Communication.

    The Politics and Mass Media section of the proceedings contains the following eight papers: "Politics and the War on Drugs: Patterns of News Coverage" (Lisa Brockmeier); "The Challenge of Bearing Witness in Political Reporting: Making the Public Conversational Partners" (Karon Reinboth Speckman); "The Concrete-Avoidance Model: Media, Public…

  16. Feasibility of histogram analysis of susceptibility-weighted MRI for staging of liver fibrosis

    PubMed Central

    Yang, Zhao-Xia; Liang, He-Yue; Hu, Xin-Xing; Huang, Ya-Qin; Ding, Ying; Yang, Shan; Zeng, Meng-Su; Rao, Sheng-Xiang

    2016-01-01

    PURPOSE We aimed to evaluate whether histogram analysis of susceptibility-weighted imaging (SWI) could quantify liver fibrosis grade in patients with chronic liver disease (CLD). METHODS Fifty-three patients with CLD who underwent multi-echo SWI (TEs of 2.5, 5, and 10 ms) were included. Histogram analysis of SWI images were performed and mean, variance, skewness, kurtosis, and the 1st, 10th, 50th, 90th, and 99th percentiles were derived. Quantitative histogram parameters were compared. For significant parameters, further receiver operating characteristic (ROC) analyses were performed to evaluate the potential diagnostic performance for differentiating liver fibrosis stages. RESULTS The number of patients in each pathologic fibrosis grade was 7, 3, 5, 5, and 33 for F0, F1, F2, F3, and F4, respectively. The results of variance (TE: 10 ms), 90th percentile (TE: 10 ms), and 99th percentile (TE: 10 and 5 ms) in F0–F3 group were significantly lower than in F4 group, with areas under the ROC curves (AUCs) of 0.84 for variance and 0.70–0.73 for the 90th and 99th percentiles, respectively. The results of variance (TE: 10 and 5 ms), 99th percentile (TE: 10 ms), and skewness (TE: 2.5 and 5 ms) in F0–F2 group were smaller than those of F3/F4 group, with AUCs of 0.88 and 0.69 for variance (TE: 10 and 5 ms, respectively), 0.68 for 99th percentile (TE: 10 ms), and 0.73 and 0.68 for skewness (TE: 2.5 and 5 ms, respectively). CONCLUSION Magnetic resonance histogram analysis of SWI, particularly the variance, is promising for predicting advanced liver fibrosis and cirrhosis. PMID:27113421

  17. A resolution honoring former President George H.W. Bush on the occasion of his 90th birthday and Barbara Bush on the occasion of her 89th birthday and extending the best wishes of the Senate to former President Bush and Mrs. Bush.

    THOMAS, 113th Congress

    Sen. Collins, Susan M. [R-ME

    2014-06-11

    06/11/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S3620; text as passed Senate: CR S3607) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  18. Vulnerability to temperature-related mortality in Seoul, Korea

    NASA Astrophysics Data System (ADS)

    Son, Ji-Young; Lee, Jong-Tae; Anderson, G. Brooke; Bell, Michelle L.

    2011-07-01

    Studies indicate that the mortality effects of temperature may vary by population and region, although little is known about the vulnerability of subgroups to these risks in Korea. This study examined the relationship between temperature and cause-specific mortality for Seoul, Korea, for the period 2000-7, including whether some subgroups are particularly vulnerable with respect to sex, age, education and place of death. The authors applied time-series models allowing nonlinear relationships for heat- and cold-related mortality, and generated exposure-response curves. Both high and low ambient temperatures were associated with increased risk for daily mortality. Mortality risk was 10.2% (95% confidence interval 7.43, 13.0%) higher at the 90th percentile of daily mean temperatures (25 °C) compared to the 50th percentile (15 °C). Mortality risk was 12.2% (3.69, 21.3%) comparing the 10th (-1 °C) and 50th percentiles of temperature. Cardiovascular deaths showed a higher risk to cold, whereas respiratory deaths showed a higher risk to heat effect, although the differences were not statistically significant. Susceptible populations were identified such as females, the elderly, those with no education, and deaths occurring outside of a hospital for heat- and cold-related total mortality. Our findings provide supportive evidence of a temperature-mortality relationship in Korea and indicate that some subpopulations are particularly vulnerable.

  19. Vulnerability to temperature-related mortality in Seoul, Korea

    PubMed Central

    Son, Ji-Young; Lee, Jong-Tae; Anderson, G Brooke; Bell, Michelle L

    2012-01-01

    Studies indicate that the mortality effects of temperature may vary by population and region, although little is known about the vulnerability of subgroups to these risks in Korea. This study examined the relationship between temperature and cause-specific mortality for Seoul, Korea, for the period 2000–7, including whether some subgroups are particularly vulnerable with respect to sex, age, education and place of death. The authors applied time-series models allowing nonlinear relationships for heat- and cold-related mortality, and generated exposure–response curves. Both high and low ambient temperatures were associated with increased risk for daily mortality. Mortality risk was 10.2% (95% confidence interval 7.43, 13.0%) higher at the 90th percentile of daily mean temperatures (25 °C) compared to the 50th percentile (15 °C). Mortality risk was 12.2% (3.69, 21.3%) comparing the 10th (−1 °C) and 50th percentiles of temperature. Cardiovascular deaths showed a higher risk to cold, whereas respiratory deaths showed a higher risk to heat effect, although the differences were not statistically significant. Susceptible populations were identified such as females, the elderly, those with no education, and deaths occurring outside of a hospital for heat- and cold-related total mortality. Our findings provide supportive evidence of a temperature–mortality relationship in Korea and indicate that some subpopulations are particularly vulnerable. PMID:23335945

  20. Evaluation of In Vitro and In Vivo Flow Rate Dependency of Budesonide/Formoterol Easyhaler®

    PubMed Central

    Malmberg, L. Pekka; Everard, Mark L.; Haikarainen, Jussi

    2014-01-01

    Abstract Background: The Easyhaler® (EH) device-metered dry powder inhaler containing budesonide and formoterol is being developed for asthma and chronic obstructive pulmonary disease (COPD). As a part of product optimization, a series of in vitro and in vivo studies on flow rate dependency were carried out. Methods: Inspiratory flow parameters via EH and Symbicort® Turbuhaler® (TH) inhalers were evaluated in 187 patients with asthma and COPD. The 10th, 50th, and 90th percentile flow rates achieved by patients were utilized to study in vitro flow rate dependency of budesonide/formoterol EH and Symbicort TH. In addition, an exploratory pharmacokinetic study on pulmonary deposition of active substances for budesonide/formoterol EH in healthy volunteers was performed. Results: Mean inspiratory flow rates through EH were 64 and 56 L/min in asthmatics and COPD patients, and through TH 79 and 72 L/min, respectively. Children with asthma had marginally lower PIF values than the adults. The inspiratory volumes were similar in all groups between the inhalers. Using weighted 10th, 50th, and 90th percentile flows the in vitro delivered doses (DDs) and fine particle doses (FPDs) for EH were rather independent of flow as 98% of the median flow DDs and 89%–93% of FPDs were delivered already at 10th percentile air flow. Using±15% limits, EH and TH had similar flow rate dependency profiles between 10th and 90th percentile flows. The pharmacokinetic study with budesonide/formoterol EH in healthy subjects (n=16) revealed a trend for a flow-dependent increase in lung deposition for both budesonide and formoterol. Conclusions: Comparable in vitro flow rate dependency between budesonide/formoterol EH and Symbicort TH was found using the range of clinically relevant flow rates. The results of the pharmacokinetic study were in accordance with the in vitro results showing only a trend of flow rate-dependant increase in lung deposition of active substances with EH. PMID:24978441

  1. A risk index for pediatric patients undergoing diagnostic imaging with 99mTc-dimercaptosuccinic acid that accounts for body habitus

    NASA Astrophysics Data System (ADS)

    O’Reilly, Shannon E.; Plyku, Donika; Sgouros, George; Fahey, Frederic H.; Treves, S. Ted; Frey, Eric C.; Bolch, Wesley E.

    2016-03-01

    Published guidelines for administered activity to pediatric patients undergoing diagnostic nuclear medicine imaging are currently obtained through expert consensus of the minimum values as a function of body weight as required to yield diagnostic quality images. We have previously shown that consideration of body habitus is also important in obtaining diagnostic quality images at the lowest administered activity. The objective of this study was to create a series of computational phantoms that realistically portray the anatomy of the pediatric patient population which can be used to develop and validate techniques to minimize radiation dose while maintaining adequate image quality. To achieve this objective, we have defined an imaging risk index that may be used in future studies to develop pediatric patient dosing guidelines. A population of 48 hybrid phantoms consisting of non-uniform B-spline surfaces and polygon meshes was generated. The representative ages included the newborn, 1 year, 5 year, 10 year and 15 year male and female. For each age, the phantoms were modeled at their 10th, 50th, and 90th height percentile each at a constant 50th weight percentile. To test the impact of kidney size, the newborn phantoms were modeled with the following three kidney volumes:  ‑15%, average, and  +15%. To illustrate the impact of different morphologies on dose optimization, we calculated the effective dose for each phantom using weight-based 99mTc-DMSA activity administration. For a given patient weight, body habitus had a considerable effect on effective dose. Substantial variations were observed in the risk index between the 10th and 90th percentile height phantoms from the 50th percentile phantoms for a given age, with the greatest difference being 18%. There was a dependence found between kidney size and risk of radiation induced kidney cancer, with the highest risk indices observed in newborns with the smallest kidneys. Overall, the phantoms and

  2. Field Measurements of Gasoline Direct Injection Emission Factors: Spatial and Seasonal Variability.

    PubMed

    Zimmerman, Naomi; Wang, Jonathan M; Jeong, Cheol-Heon; Ramos, Manuel; Hilker, Nathan; Healy, Robert M; Sabaliauskas, Kelly; Wallace, James S; Evans, Greg J

    2016-02-16

    Four field campaigns were conducted between February 2014 and January 2015 to measure emissions from light-duty gasoline direct injection (GDI) vehicles (2013 Ford Focus) in an urban near-road environment in Toronto, Canada. Measurements of CO2, CO, NOx, black carbon (BC), benzene, toluene, ethylbenzene-xylenes (BTEX), and size-resolved particle number (PN) were recorded 15 m from the roadway and converted to fuel-based emission factors (EFs). Other than for NOx and CO, the GDI engine had elevated emissions compared to the Toronto fleet, with BC EFs in the 73rd percentile, BTEX EFs in the 80-90th percentile, and PN EFs in the 75th percentile during wintertime measurements. Additionally, for three campaigns, a second platform for measuring PN and CO2 was placed 1.5-3 m from the roadway to quantify changes in PN with distance from point of emission. GDI vehicle PN EFs were found to increase by up to 240% with increasing distance from the roadway, predominantly due to an increasing fraction of sub-40 nm particles. PN and BC EFs from the same engine technology were also measured in the laboratory. BC EFs agreed within 20% between the laboratory and real-world measurements; however, laboratory PN EFs were an order of magnitude lower due to exhaust conditioning. PMID:26794244

  3. Linkage Between Hourly Precipitation Events and Atmospheric Temperature Changes over China during the Warm Season

    PubMed Central

    Miao, Chiyuan; Sun, Qiaohong; Borthwick, Alistair G. L.; Duan, Qingyun

    2016-01-01

    We investigated changes in the temporospatial features of hourly precipitation during the warm season over mainland China. The frequency and amount of hourly precipitation displayed latitudinal zonation, especially for light and moderate precipitation, which showed successive downward change over time in northeastern and southern China. Changes in the precipitation amount resulted mainly from changes in frequency rather than changes in intensity. We also evaluated the linkage between hourly precipitation and temperature variations and found that hourly precipitation extreme was more sensitive to temperature than other categories of precipitation. A strong dependency of hourly precipitation on temperature occurred at temperatures colder than the median daily temperature; in such cases, regression slopes were greater than the Clausius-Clapeyron (C-C) relation of 7% per degree Celsius. Regression slopes for 31.6%, 59.8%, 96.9%, and 99.1% of all stations were greater than 7% per degree Celsius for the 75th, 90th, 99th, and 99.9th percentiles for precipitation, respectively. The mean regression slopes within the 99.9th percentile of precipitation were three times the C-C rate. Hourly precipitation showed a strong negative relationship with daily maximum temperature and the diurnal temperature range at most stations, whereas the equivalent correlation for daily minimum temperature was weak. PMID:26931350

  4. Air Pollution and the Risk of Cardiac Defects

    PubMed Central

    Hwang, Bing-Fang; Lee, Yungling Leo; Jaakkola, Jouni J.K.

    2015-01-01

    Abstract Previous epidemiologic studies have assessed the role of the exposure to ambient air pollution in the development of cardiac birth defects, but they have provided somewhat inconsistent results. To assess the associations between exposure to ambient air pollutants and the risk of cardiac defects, a population-based case-control study was conducted using 1087 cases of cardiac defects and a random sample of 10,870 controls from 1,533,748 Taiwanese newborns in 2001 to 2007. Logistic regression was performed to calculate odds ratios for 10 ppb increases in O3 and 10 μg/m3 increases in PM10. In addition, we compared the risk of cardiac defects in 4 categories-high exposure (>75th percentile); medium exposure (75th to 50th percentile); low exposure (<50th–25th percentile); reference (<25th percentile) based on the distribution of each pollutant. The risks of ventricular septal defects (VSD), atrial septal defects (ASD), and patent ductus arteriosus (PDA) were associated with 10 ppb increases in O3 exposure during the first 3 gestational months among term and preterm babies. In comparison between high PM10 exposure and reference category, there were statistically significant elevations in the effect estimates of ASD for all and terms births. In addition, there was a negative or weak association between SO2, NO2, CO, and cardiac defects. The study proved that exposure to outdoor air O3 and PM10 during the first trimester of gestation may increase the risk of VSD, ASD, and PDA. PMID:26554783

  5. ENSO and hydrologic extremes in the western United States

    USGS Publications Warehouse

    Cayan, D.R.; Redmond, K.T.; Riddle, L.G.

    1999-01-01

    Frequency distributions of daily precipitation in winter and daily stream flow from late winter to early summer, at several hundred sites in the western United States, exhibit strong and systematic responses to the two phases of ENSO. Most of the stream flows considered are driven by snowmelt. The Southern Oscillation index (SOI) is used as the ENSO phase indicator. Both modest (median) and larger (90th percentile) events were considered. In years with negative SOI values (El Nino), days with high daily precipitation and stream flow are more frequent than average over the Southwest and less frequent over the Northwest. During years with positive SOI values (La Nina), a nearly opposite pattern is seen. A more pronounced increase is seen in the number of days exceeding climatological 90th percentile values than in the number exceeding climatological 50th percentile values, for both precipitation and stream flow. Stream flow responses to ENSO extremes are accentuated over precipitation responses. Evidence suggests that the mechanism for this amplification involves ENSO-phase differences in the persistence and duration of wet episodes, affecting the efficiency of the process by which precipitation is converted to runoff. The SOI leads the precipitation events by several months, and hydrologic lags (mostly through snowmelt) dealy the stream flow response by several more months. The combined 6-12 month predictive aspect of this relationship should be of significant benefit in responding to flood (or drought) risk and in improving overall water management in the western states.Frequency distributions of daily precipitation in winter and daily stream flow from late winter to early summer, at several hundred sites in the western United States, exhibit strong and systematic responses to the two phases of ENSO. Most of the stream flows considered are driven by snowmelt. The Southern Oscillation index (SOI) is used as the ENSO phase indicator. Both modest (median) and larger

  6. Risk Assessment of Arsenic in Rice Cereal and Other Dietary Sources for Infants and Toddlers in the U.S.

    PubMed

    Shibata, Tomoyuki; Meng, Can; Umoren, Josephine; West, Heidi

    2016-01-01

    Currently, there are no set standards or quantitative guidelines available in the U.S. for arsenic levels in rice cereal, one of the most common first solid foods for infants. The objective of this study was to evaluate whether the detected levels of inorganic arsenic (Asi) in rice cereal in the U.S. market are safe for consumption by infants and toddlers. A risk assessment was conducted based on literature reviews of the reported Asi in rice cereal from the U.S. Food and Drug Administration's (FDA) survey and the recommended daily intake of rice cereal by body weight, for infants and toddlers between four and 24 months old. As a part of risk management, a maximum contaminant level (MCL) for Asi in rice cereal was computed considering overall exposure sources including drinking water, infant formula, and other infant solid foods. Hazard quotients (HQs) for acute and chronic exposures were calculated based on the U.S. Agency for Toxic Substances and Disease Registry's (ATSDR) Minimal Risk Level (MRL)acute (5.0 × 10(-3) mg/kg/day) and MRLchronic (3.0 × 10(-4) mg/kg/day). A cancer slope or potency factor of 1.5 mg/kg/day was used to predict an incremental lifetime cancer risk (ILCR). Exposure assessment showed that the largest source of Asi for infants and toddlers between four and 24 months old was rice cereal (55%), followed by other infant solid food (19%), and drinking water (18%). Infant formula was the smallest source of Asi for babies (9%) at the 50th percentile based on Monte Carlo simulations. While HQacute were consistently below 1.0, HQchronic at the 50 and 75th percentiles exceeded 1.0 for both rice cereal and total sources. ILCR ranged from 10(-6) (50th) to 10(-5) (75th percentile). MCLs for Asi in rice cereal ranged from 0.0 (chronic) to 0.4 mg/kg (acute exposures). PMID:27023581

  7. Risk Assessment of Arsenic in Rice Cereal and Other Dietary Sources for Infants and Toddlers in the U.S.

    PubMed Central

    Shibata, Tomoyuki; Meng, Can; Umoren, Josephine; West, Heidi

    2016-01-01

    Currently, there are no set standards or quantitative guidelines available in the U.S. for arsenic levels in rice cereal, one of the most common first solid foods for infants. The objective of this study was to evaluate whether the detected levels of inorganic arsenic (Asi) in rice cereal in the U.S. market are safe for consumption by infants and toddlers. A risk assessment was conducted based on literature reviews of the reported Asi in rice cereal from the U.S. Food and Drug Administration’s (FDA) survey and the recommended daily intake of rice cereal by body weight, for infants and toddlers between four and 24 months old. As a part of risk management, a maximum contaminant level (MCL) for Asi in rice cereal was computed considering overall exposure sources including drinking water, infant formula, and other infant solid foods. Hazard quotients (HQs) for acute and chronic exposures were calculated based on the U.S. Agency for Toxic Substances and Disease Registry’s (ATSDR) Minimal Risk Level (MRL)acute (5.0 × 10−3 mg/kg/day) and MRLchronic (3.0 × 10−4 mg/kg/day). A cancer slope or potency factor of 1.5 mg/kg/day was used to predict an incremental lifetime cancer risk (ILCR). Exposure assessment showed that the largest source of Asi for infants and toddlers between four and 24 months old was rice cereal (55%), followed by other infant solid food (19%), and drinking water (18%). Infant formula was the smallest source of Asi for babies (9%) at the 50th percentile based on Monte Carlo simulations. While HQacute were consistently below 1.0, HQchronic at the 50 and 75th percentiles exceeded 1.0 for both rice cereal and total sources. ILCR ranged from 10−6 (50th) to 10−5 (75th percentile). MCLs for Asi in rice cereal ranged from 0.0 (chronic) to 0.4 mg/kg (acute exposures). PMID:27023581

  8. The association between farming activities, precipitation, and the risk of acute gastrointestinal illness in rural municipalities of Quebec, Canada: a cross-sectional study

    PubMed Central

    2010-01-01

    Background Increasing livestock density and animal manure spreading, along with climate factors such as heavy rainfall, may increase the risk of acute gastrointestinal illness (AGI). In this study we evaluated the association between farming activities, precipitation and AGI. Methods A cross-sectional telephone survey of randomly selected residents (n = 7006) of 54 rural municipalities in Quebec, Canada, was conducted between April 2007 and April 2008. AGI symptoms and several risk factors were investigated using a phone questionnaire. We calculated the monthly prevalence of AGI, and used multivariate logistic regression, adjusting for several demographic and risk factors, to evaluate the associations between AGI and both intensive farming activities and cumulative weekly precipitation. Cumulative precipitation over each week, from the first to sixth week prior to the onset of AGI, was analyzed to account for both the delayed effect of precipitation on AGI, and the incubation period of causal pathogens. Cumulative precipitation was treated as a four-category variable: high (≥90th percentile), moderate (50th to <90th percentile), low (10th to <50th percentile), and very low (<10th percentile) precipitation. Results The overall monthly prevalence of AGI was 5.6% (95% CI 5.0%-6.1%), peaking in winter and spring, and in children 0-4 years old. Living in a territory with intensive farming was negatively associated with AGI: adjusted odds ratio (OR) = 0.70 (95% CI 0.51-0.96). Compared to low precipitation periods, high precipitation periods in the fall (September, October, November) increased the risk of AGI three weeks later (OR = 2.20; 95% CI 1.09-4.44) while very low precipitation periods in the summer (June, July, August) increased the risk of AGI four weeks later (OR = 2.19; 95% CI 1.02-4.71). Further analysis supports the role of water source on the risk of AGI. Conclusions AGI poses a significant burden in Quebec rural municipalities with a peak in winter

  9. Forest-Water Feedbacks Under a Changing Climate

    NASA Astrophysics Data System (ADS)

    Creed, I. F.; Hwang, T.

    2015-12-01

    Among the most valuable products produced by forests are the ecosystem services of safe and reliable water supplies. The provision of these ecosystem services on forested landscapes is inherently linked to forest condition. Climate change and associated hydrological intensification may affect forest water use (green water) and runoff generation (blue water) in the temperate forest biome of eastern North America. For the time period from the 1980s to present, a period with significant climate warming, we used a network of long-term catchment study sites nested within the temperate forest biome to explore forest-water feedbacks in response to climate change. Satellite remote sensing was used to track changes in forest phenology and forest productivity, and catchment meteorological and discharge records were used to track changes in the magnitude and timing of forest water yields. Forest responses to climate change varied along a latitudinal gradient. The magnitude of annual water yields declined at all study sites. The timing of peak discharge was measured by the center of mass (i.e., 50th percentile), and the narrowing or widening of discharge periods was measured by the coefficient of dispersion (i.e., 75th - 25th over 50th percentile) of water yield. For the vernal window, we observed subtle and systematic changes with a shift to later peaks in the center of mass of spring discharge and a widening of the spring discharge period (i.e., less peaked flows). For the autumnal window, we observed less subtle, non-systematic changes with a shift to later peaks above 45 degrees latitude but earlier peaks below 45 degrees latitude, and a narrowing of the fall discharge period (i.e., more peaked flows). The time shift and widening of vernal and autumnal windows are likely caused by asymmetric responses of forest water use (green water) and runoff generation (blue water) to climate warming. These disruptions in forest-water coupling are likely to have significant

  10. A resolution recognizing the 50th anniversary of the date of enactment of the law that created real estate investment trusts (REITs) and gave millions of Americans new investment opportunities that helped them build a solid foundation for retirement and has contributed to the overall strength of the economy of the United States.

    THOMAS, 112th Congress

    Sen. Isakson, Johnny [R-GA

    2011-02-17

    02/17/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S923-924; text as passed Senate: CR S923-924; text of measure as introduced: CR S912-913) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  11. A bill to award posthumously a Congressional Gold Medal to Addie Mae Collins, Denise McNair, Carole Robertson, and Cynthia Wesley, in recognition of the 50th anniversary of the bombing of the Sixteenth Street Baptist Church, where the 4 little Black girls lost their lives, which served as a catalyst for the Civil Rights Movement.

    THOMAS, 113th Congress

    Sen. Shelby, Richard C. [R-AL

    2013-01-30

    01/30/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Notes: For further action, see H.R.360, which became Public Law 113-11 on 5/24/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  12. A resolution recognizing the 50th anniversary of "Smoking and Health: Report of the Advisory Committee to the Surgeon General of the United States" and the significant progress in reducing the public health burden of tobacco use, and supporting an end to tobacco-related death and disease.

    THOMAS, 113th Congress

    Sen. Blumenthal, Richard [D-CT

    2014-01-13

    01/13/2014 Referred to the Committee on Health, Education, Labor, and Pensions. (text of measure as introduced: CR S292) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  13. S.Res.60 — 112th Congress (2011-2012) A resolution recognizing the 50th anniversary of the date of enactment of the law that created real estate investment trusts (REITs) and gave millions of Americans new investment opportunities that...

    THOMAS, 112th Congress

    Sen. Isakson, Johnny [R-GA

    2011-02-17

    02/17/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S923-924; text as passed Senate: CR S923-924; text of measure as introduced: CR S912-913) (All Actions)

  14. A resolution congratulating the 1963 men's basketball team of Loyola University Chicago on its induction into the National Collegiate Basketball Hall of Fame, the 50th anniversary of the team's Division I National Collegiate Athletic Association men's basketball championship, and the team's historic NCAA tournament game against Mississippi State University.

    THOMAS, 113th Congress

    Sen. Kirk, Mark Steven [R-IL

    2013-07-10

    07/10/2013 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S5622) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. Ivsite, Na3H(SO4)2, a new mineral from volcanic exhalations of fumaroles of the Fissure Tolbachik Eruption of the 50th Anniversary of the Institute of Volcanology and Seismology, Far East Branch, Russian Academy of Sciences

    NASA Astrophysics Data System (ADS)

    Filatov, S. K.; Karpov, G. A.; Shablinskii, A. P.; Krivovichev, S. V.; Vergasova, L. P.; Antonov, A. V.

    2016-06-01

    Fine-granular (<0.1 mm) flattened colorless transparent crystals of ivsite form white aggregates. The empirical formula (Na2.793Cu0.056)2.849HS2.016O8 is close to the ideal Na3H(SO4)2. The structure was refined up to R = 0.040. Ivsite has a monoclinic symmetry, P21/ c, a = 8.655(1) Å, b = 9.652(1) Å, c = 9.147(1) Å, β = 108.76(1)°, V = 723.61(1) Å3, Z = 4. Na atoms occur at six- and seven-fold sites (NaO6 and NaO7); S atoms, in isolated SO4 tetrahedrons; these polyhedrons form a three-dimensional framework. The diagnostic lines of powder diffraction patterns ( d[Å]- I- hkl) are 4.010-53-12-1, 3.949-87-012, 3.768-100-210, 3.610-21-20-2, 3.022-22-031, 2.891-42-22-2, 2.764-49-31-1, and 2.732-70-13-1.

  16. A resolution recognizing the 50th anniversary of the Great Alaska Earthquake, which struck the State of Alaska at 5:36 p.m. on Good Friday, March 27, 1964, honoring those who lost their lives in the Great Alaska Earthquake and associated tsunamis, and expressing continued support for research on earthquake and tsunami prediction and mitigation strategies.

    THOMAS, 113th Congress

    Sen. Murkowski, Lisa [R-AK

    2014-03-27

    03/27/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S1800-1803; text as passed Senate: CR S1831) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  17. Long-lasting genomic instability following arsenite exposure in mammalian cells: the role of reactive oxygen species.

    PubMed

    Sciandrello, G; Mauro, M; Catanzaro, I; Saverini, M; Caradonna, F; Barbata, G

    2011-08-01

    Previously, we reported that the progeny of mammalian cells, which has been exposed to sodium arsenite for two cell cycles, exhibited chromosomal instability and concurrent DNA hypomethylation, when they were subsequently investigated after two months of subculturing (about 120 cell generations) in arsenite-free medium. In this work, we continued our investigations of the long-lasting arsenite-induced genomic instability by analyzing additional endpoints at several time points during the cell expanded growth. In addition to the progressive increase of aneuploid cells, we also noted micronucleated and multinucleated cells that continued to accumulate up to the 50th cell generation, as well as dicentric chromosomes and/or telomeric associations and other complex chromosome rearrangements that began to appear much later, at the 90th cell generation following arsenite exposure. The increasing genomic instability was further characterized by an increased frequency of spontaneous mutations. Furthermore, the long-lasting genomic instability was related to elevated levels of reactive oxygen species (ROS), which at the 50th cell generation appeared higher than in stable parental cells. To gain additional insight into the continuing genomic instability, we examined several individual clones isolated at different time points from the growing cell population. Chromosomally and morphologically unstable cell clones, the number of which increased with the expanded growth, were also present at early phases of growth without arsenite. All genomically unstable clones exhibited higher ROS levels than untreated cells suggesting that oxidative stress is an important factor for the progression of genomic instability induced by arsenite. PMID:21520292

  18. Estimation of dietary exposure to acrylamide of Polish teenagers from an urban environment.

    PubMed

    Wyka, Joanna; Tajner-Czopek, Agnieszka; Broniecka, Anna; Piotrowska, Ewa; Bronkowska, Monika; Biernat, Jadwiga

    2015-01-01

    The aim of this study was to evaluate the dietary exposure to acrylamide (AA) in a group of teenagers (n = 261) from an urban environment. The intake of AA from food was estimated based on a 7-day food record diary (consecutive days). The food rations obtained (n = 1827) were used to calculate the amounts of the consumed food products, which were the main sources of AA. In the case of girls, the estimated dietary intake of AA per kg body weight (BW) amounted to 0.09 µg/kg BW/day (50th percentile), 0.32 µg/kg BW/day (75th percentile) and 1.04 µg/kg BW/day (95th percentile), and among boys it was 0.13, 0.41, and 1.18 µg/kg BW/day, respectively. The main sources of AA exposure were French fries, potato crisps, corn flakes, bread and salty sticks. The lowest values for margin of exposure (MOE) were calculated for the P95th percentiles of exposure, and ranged from 152 to 173. PMID:25445510

  19. Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women.

    PubMed

    Teeguarden, Justin G; Twaddle, Nathan C; Churchwell, Mona I; Doerge, Daniel R

    2016-06-01

    Despite its very low oral bioavailability and rapid elimination, multiple reports of unexpectedly high bisphenol A (BPA) concentrations in the serum of pregnant mothers or cord blood have raised questions about BPA exposures during pregnancy. Thirty healthy pregnant women recruited to the study were evaluated for total BPA exposure over a 30-h period comprising one-half day in the field and one day in a clinical setting. BPA and its metabolites were measured in serum and total BPA was measured in matching urine samples. The mean total exposure was similar to the 50(th) percentile of exposure for U.S. women and pregnant women in a large North American cohort. Twenty volunteers had total daily exposures equal to or exceeding the U.S. mean, and six volunteers had exposures exceeding the 75th percentile. Women working as cashiers did not have higher total BPA exposure. BPA was detected in some serum samples (0.25-0.51 ng/ml), but showed no relationship to total BPA in corresponding urine samples, no relationship to total BPA exposure, and had unconjugated BPA fractions of 60-80%, consistent with established criteria for sample contamination. We conclude that typical exposures of North American pregnant women produce internal exposures to BPA in the picomolar range. PMID:27038865

  20. Multi-host model and threshold of intermediate host Oncomelania snail density for eliminating schistosomiasis transmission in China.

    PubMed

    Zhou, Yi-Biao; Chen, Yue; Liang, Song; Song, Xiu-Xia; Chen, Geng-Xin; He, Zhong; Cai, Bin; Yihuo, Wu-Li; He, Zong-Gui; Jiang, Qing-Wu

    2016-01-01

    Schistosomiasis remains a serious public health issue in many tropical countries, with more than 700 million people at risk of infection. In China, a national integrated control strategy, aiming at blocking its transmission, has been carried out throughout endemic areas since 2005. A longitudinal study was conducted to determine the effects of different intervention measures on the transmission dynamics of S. japonicum in three study areas and the data were analyzed using a multi-host model. The multi-host model was also used to estimate the threshold of Oncomelania snail density for interrupting schistosomiasis transmission based on the longitudinal data as well as data from the national surveillance system for schistosomiasis. The data showed a continuous decline in the risk of human infection and the multi-host model fit the data well. The 25th, 50th and 75th percentiles, and the mean of estimated thresholds of Oncomelania snail density below which the schistosomiasis transmission cannot be sustained were 0.006, 0.009, 0.028 and 0.020 snails/0.11 m(2), respectively. The study results could help develop specific strategies of schistosomiasis control and elimination tailored to the local situation for each endemic area. PMID:27535177

  1. Hydrologic data for the Larimer-Weld regional water-monitoring program, Colorado, 1975-82

    USGS Publications Warehouse

    Blakely, S.R.; Steinheimer, J.T.

    1984-01-01

    The Larimer-Weld, Colorado, regional Monitoring Program was begun in 1976 to provide information on the quality and quantity of the surface-water resources in the area. Three stations on the big Thompson River and five stations on the Cache La Poudre River were selected for a data-collection network. Four previously established stations were added to complete the data-collection network: Horsetooth Reservoir, Joe Wright Creek above and below Joe Wright Reservoir, and Michigan River near Cameron Pass. Station description, location, and period of record are given for each station. A statistical summary of the water-quality data for each station is tabulated. Frequency of occurrence is given at the 95th, 75th, 50th, and 25th percentiles. Monthly water-quality data and daily average streamflow data are tabulated for each streamflow station for which this data was collected; Monthly contents data are presented for Horsetooth Reservoir. All data tabulated and summarized are from the period October 1, 1975, through September 30, 1982. (USGS)

  2. Heavy metals in aquatic organisms of different trophic levels and their potential human health risk in Bohai Bay, China.

    PubMed

    Zhang, Yan; Lu, Xueqiang; Wang, Naili; Xin, Meinan; Geng, Shiwei; Jia, Jing; Meng, Qinghui

    2016-09-01

    Fourteen aquatic organism samples were collected from Bohai Bay, and concentrations of five heavy metals were measured to evaluate the pollution levels in aquatic organisms and the potential risk to human health. The concentrations of Zn and Cu were much higher than those of Cd, Cr, and Pb in all the organisms. In general, the heavy metal concentration levels were in the order phytoplankton < zooplankton < fish < shrimp < shellfish. Heavy metal concentrations in higher trophic-level aquatic organisms in Bohai Bay were compared to those in the organisms from other worldwide coastal waters. The concentration levels of most heavy metals were higher than the 75th percentile, except that Pb concentration was between the 25th and 50th percentiles. The calculated bioconcentration factors (BCF) of Cr, Cu, and Pb for phytoplankton were less than 100, indicating no accumulation in primary producers. The bioaccumulation factor (BAF) of Pb for zooplankton was the highest, indicating significant Pb accumulation in zooplankton. For higher trophic-level aquatic organisms, the order of BAF values was fish < shrimp < shellfish for most metals except for Pb. The human health risk assessment suggests that strict abatement measures of heavy metals must be taken to decrease the health risk caused by consuming aquatic products. PMID:27250089

  3. A Patient-Centered Electronic Tool for Weight Loss Outcomes after Roux-en-Y Gastric Bypass

    PubMed Central

    Gerhard, Glenn S.; Miller, Elaina K.; Zaccone, Richard J.; Argyropoulos, George A.; Petrick, Anthony T.; Still, Christopher D.

    2014-01-01

    Background. Current patient education and informed consent regarding weight loss expectations for bariatric surgery candidates are largely based on averages from large patient cohorts. The variation in weight loss outcomes illustrates the need for establishing more realistic weight loss goals for individual patients. This study was designed to develop a simple web-based tool which provides patient-specific weight loss expectations. Methods. Postoperative weight measurements after Roux-en-Y gastric bypass (RYGB) were collected and analyzed with patient characteristics known to influence weight loss outcomes. Quantile regression was used to create expected weight loss curves (25th, 50th, and 75th %tile) for the 24 months after RYGB. The resulting equations were validated and used to develop web-based tool for predicting weight loss outcomes. Results. Weight loss data from 2986 patients (2608 in the primary cohort and 378 in the validation cohort) were included. Preoperative body mass index (BMI) and age were found to have a high correlation with weight loss accomplishment (P < 0.0001 for each). An electronic tool was created that provides easy access to patient-specific, 24-month weight loss trajectories based on initial BMI and age. Conclusions. This validated, patient-centered electronic tool will assist patients and providers in patient teaching, informed consent, and postoperative weight loss management. PMID:24772350

  4. Multi-host model and threshold of intermediate host Oncomelania snail density for eliminating schistosomiasis transmission in China

    PubMed Central

    Zhou, Yi-Biao; Chen, Yue; Liang, Song; Song, Xiu-Xia; Chen, Geng-Xin; He, Zhong; Cai, Bin; Yihuo, Wu-Li; He, Zong-Gui; Jiang, Qing-Wu

    2016-01-01

    Schistosomiasis remains a serious public health issue in many tropical countries, with more than 700 million people at risk of infection. In China, a national integrated control strategy, aiming at blocking its transmission, has been carried out throughout endemic areas since 2005. A longitudinal study was conducted to determine the effects of different intervention measures on the transmission dynamics of S. japonicum in three study areas and the data were analyzed using a multi-host model. The multi-host model was also used to estimate the threshold of Oncomelania snail density for interrupting schistosomiasis transmission based on the longitudinal data as well as data from the national surveillance system for schistosomiasis. The data showed a continuous decline in the risk of human infection and the multi-host model fit the data well. The 25th, 50th and 75th percentiles, and the mean of estimated thresholds of Oncomelania snail density below which the schistosomiasis transmission cannot be sustained were 0.006, 0.009, 0.028 and 0.020 snails/0.11 m2, respectively. The study results could help develop specific strategies of schistosomiasis control and elimination tailored to the local situation for each endemic area. PMID:27535177

  5. Individual estimation of exposures to extremely low frequency magnetic fields in jobs commonly held by women.

    PubMed

    Deadman, J E; Infante-Rivard, C

    2002-02-15

    Exposures to extremely low frequency (ELF) magnetic fields have not been documented extensively in occupations besides the work environments of electric or telephone utilities. A 1980-1993 study of childhood acute lymphoblastic leukemia (ALL) in Québec, Canada, gathered detailed information about the occupations of 491 mothers of ALL cases and mothers of a similar number of healthy controls. This information was combined with published data on the intensities of ELF magnetic fields associated with sources or work environments to estimate ELF magnetic field exposures for a wide range of jobs commonly held by women. Estimated exposures for 61 job categories ranged from 0.03 to 0.68 microT; the 25th, 50th, and 75th percentiles were 0.135, 0.17, and 0.23 microT, respectively. By job category, the most highly exposed jobs (>0.23 microT) included bakery worker, cashier, cook and kitchen worker, electronics worker, residential and industrial sewing machine operator, and textile machine operator. By work environment, the most highly exposed job categories were electronics worker in an assembly plant (0.70 microT) and sewing machine operators in a textile factory (0.68 microT) and shoe factory (0.66 microT). These results provide new information on expected levels of exposure in a wide range of jobs commonly held by women. PMID:11836202

  6. Do the pre-service education programmes for midwives in India prepare confident ‘registered midwives’? A survey from India

    PubMed Central

    Sharma, Bharati; Hildingsson, Ingegerd; Johansson, Eva; Prakasamma, Malvarappu; Ramani, K.V.; Christensson, Kyllike

    2015-01-01

    Objective The graduates of the diploma and degree programmes of nursing and midwifery in India are considered skilled birth attendants (SBAs). This paper aimed to assess the confidence of final-year students from pre-service education programmes (diploma and bachelor's) in selected midwifery skills from the list of midwifery competencies of the International Confederation of Midwives (ICM). Design A cross-sectional survey was conducted in Gujarat, India, involving 633 final-year students from 25 educational institutions (private or government), randomly selected, stratified by the type of programme (diploma and bachelor's). Students assessed their confidence on a four-point scale, in four midwifery competency domains – antepartum, intrapartum, postpartum, and newborn care. Explorative factor analysis was used to reduce skill statements into separate subscales for each domain. Results Overall, 25–40% of students scored above the 75th percentile and 38–50% below the 50th percentile of confidence in all subscales for antepartum, intrapartum, postpartum, and newborn care. The majority had not attended the required number of births prescribed by the Indian Nursing Council. Conclusions The pre-service education offered in the diploma and bachelor's programmes in Gujarat does not prepare confident SBAs, as measured on selected midwifery competencies of the ICM. One of the underlying reasons was less clinical experience during their education. The duration, content, and pedagogy of midwifery education within the integrated programmes need to be reviewed. PMID:26649550

  7. Percentile Distributions of Median Nitrite Plus Nitrate as Nitrogen, Total Nitrogen, and Total Phosphorus Concentrations in Oklahoma Streams, 1973-2001

    USGS Publications Warehouse

    Haggard, Brian E.; Masoner, Jason R.; Becker, Carol J.

    2003-01-01

    Nutrients are one of the primary causes of water-quality impairments in streams, lakes, reservoirs, and estuaries in the United States. The U.S. Environmental Protection Agency has developed regional-based nutrient criteria using ecoregions to protect streams in the United States from impairment. However, nutrient criteria were based on nutrient concentrations measured in large aggregated nutrient ecoregions with little relevance to local environmental conditions in states. The Oklahoma Water Resources Board is using a dichotomous process known as Use Support Assessment Protocols to define nutrient criteria in Oklahoma streams. The Oklahoma Water Resources Board is modifying the Use Support Assessment Protocols to reflect nutrient informa-tion and environmental characteristics relevant to Oklahoma streams, while considering nutrient information grouped by geographic regions based on level III ecoregions and state boundaries. Percentile distributions of median nitrite plus nitrate as nitrogen, total nitrogen, and total phosphorous concentrations were calculated from 563 sites in Oklahoma and 4 sites in Arkansas near the Oklahoma and Arkansas border to facilitate development of nutrient criteria for Oklahoma streams. Sites were grouped into four geographic regions and were categorized into eight stream categories by stream slope and stream order. The 50th percentiles of median nitrite plus nitrate as nitrogen, total nitrogen, and total phosphorus concentrations were greater in the Ozark Highland ecoregion and were less in the Ouachita Mountains ecoregion when compared to other geographic areas used to group sites. The 50th percentiles of median concentrations of nitrite plus nitrate as nitrogen, total nitrogen, and total phosphorus were least in first, second, and third order streams. The 50th percentiles of median nitrite plus nitrate as nitrogen, total nitrogen and total phosphorus concentrations in the Ozark Highland and Ouachita Mountains ecoregions were least in

  8. Aggressive blood pressure control for chronic kidney disease unmasks moyamoya!

    PubMed Central

    Davis, T. Keefe; Halabi, Carmen M.; Siefken, Philp; Karmarkar, Swati; Leonard, Jeffrey

    2013-01-01

    Hypertensive crises in children or adolescents are rare, but chronic kidney disease (CKD) is a major risk factor for occurrence. Vesicoureteral reflux nephropathy is a common cause of pediatric renal failure and is associated with hypertension. Aggressive blood pressure (BP) control has been shown to delay progression of CKD and treatment is targeted for the 50th percentile for height when compared with a target below the 90th percentile for the general pediatric hypertensive patient. We present a case of an adolescent presenting with seizures and renal failure due to a hypertensive crisis. Hypertension was thought to be secondary to CKD as she had scarred echogenic kidneys due to known reflux nephropathy. However, aggressive BP treatment improved kidney function which is inconsistent with CKD from reflux nephropathy. Secondly, aggressive BP control caused transient neurological symptoms. Further imaging identified moyamoya disease. We present this case to highlight the consideration of moyamoya as a diagnosis in the setting of renal failure and hypertensive crisis. PMID:26064513

  9. Tackling 30-Day, All-Cause Readmissions with a Patient-Centered Transitional Care Bundle.

    PubMed

    Rice, Yvonne B; Barnes, Carol Ann; Rastogi, Rahul; Hillstrom, Tami J; Steinkeler, Cara N

    2016-02-01

    In 2008, Kaiser Permanente Northwest identified the transition from hospital to home as a pivotal quality improvement opportunity and used multiple patient-centered data collection methods to identify unmet needs contributing to preventable readmissions. A transitional care bundle that crosses care settings and organizational functions was developed to meet needs expressed by patients. It comprises 5 elements: risk stratification, a specialized phone number for discharged patients, timely postdischarge follow-up, standardized patient discharge instructions and same-day discharge summaries, and pharmacist-supported medication reconciliation. The transitional care bundle has been in place for 6 years. Readmission rates decreased from 12.1% to 10.6%, Hospital Consumer Assessment of Healthcare Providers and Systems scores for the discharge instruction composite moved from below the 50(th) to above the 90(th) national percentile, average time to the first postdischarge appointment decreased from 9.7 days to 5.3 days, and error rates on the discharge medication list decreased from 57% to 21% (P<.0001 for all). The program, which continues to evolve to address sustainability challenges and organizational initiatives, suggests the potential of a multicomponent, patient-centered care bundle to address the complex, interrelated drivers of preventable readmissions. PMID:25919315

  10. Probabilistic Monte Carlo estimation for quantitative exposure assessment of lotion transfer via baby wipes usage.

    PubMed

    Dey, Swatee; Carr, Gregory J; Li, Lijuan; Brink, Susanna; Zhou, Shaoying

    2016-08-01

    Unique aspects of childhood exposure to products need childs specific exposure data. This study developed a probabilistic exposure model for lotion transfer to diapered skin through normal use of baby wipes in children up to 48 months of age. Monte Carlo simulations used baby wipe diary data from the US, Germany and the UK, body weight data from the US, and lotion transfer data from single and multiple wipes adjusting for separate diaper changes. The models predicted a declining number of wipes used/day with a reduction in lotion transfer as age and body weight increased. Experimental testing on multiple sequential wipes used on an overlapping area showed a reduction in lotion deposition by 23.9% after the first wipe. Overall, the weighted population average over the approximate diapering period of 0-36 months across the three geographies at 50th, 90th, & 95th percentiles, were between 130, 230, 260 mg/kg/day, respectively, and 150, 270, 310 mg/kg/day depending on whether a reduction due to overlap is implemented. The statistical model represents an effective strategy to determine exposure to baby wipes lotion for exposure based risk assessment. PMID:27184939

  11. Temporal characteristics of the speech of typical and lexically precocious two-year-old children: preliminary observations

    NASA Astrophysics Data System (ADS)

    Smith, Bruce L.; McGregor, Karla K.

    2002-05-01

    To examine the extent to which temporal properties of speech might be affected by children's lexical knowledge as opposed to their age and general development, productions by a group of two-year-olds with average-sized vocabularies were compared with those of a group of age-matched, lexically precocious children. It was hypothesized that because of their additional lexical knowledge and experience, the lexically precocious children would manifest shorter durations and/or less temporal variability in their speech. Multiple repetitions of several different target words were obtained from children with vocabularies at about the 50th percentile (ca. 300 words) versus the 90th percentile (ca. 600 words) on the MacArthur Communicative Development Inventory. In general, acoustic measurements indicated that there were no significant differences between the groups in terms of their segmental durations or temporal variability. Thus, the additional linguistic knowledge and experience the precocious talkers had gained from having learned to produce many more words did not appear to have influenced temporal properties of their speech. This suggests that the children's age and/or other aspects of their development had a greater impact on temporal aspects of their speech than did their level of lexical knowledge and experience.

  12. Physical activity, motor function, and white matter hyperintensity burden in healthy older adults

    PubMed Central

    Yang, Jingyun; Arfanakis, Konstantinos; Arvanitakis, Zoe; Leurgans, Sue E.; Turner, Arlener D.; Barnes, Lisa L.; Bennett, David A.; Buchman, Aron S.

    2015-01-01

    Objective: To test the hypothesis that physical activity modifies the association between white matter hyperintensity (WMH) burden and motor function in healthy older persons without dementia. Methods: Total daily activity (exercise and nonexercise physical activity) was measured for up to 11 days with actigraphy (Actical; Philips Respironics, Bend, OR) in 167 older adults without dementia participating in the Rush Memory and Aging Project. Eleven motor performances were summarized into a previously described global motor score. WMH volume was expressed as percent of intracranial volume. Linear regression models, adjusted for age, education, and sex, were performed with total WMH volume as the predictor and global motor score as the outcome. Terms for total daily physical activity and its interaction with WMH volume were then added to the model. Results: Higher WMH burden was associated with lower motor function (p = 0.006), and total daily activity was positively associated with motor function (p = 0.002). Total daily activity modified the association between WMH and motor function (p = 0.007). WMH burden was not associated with motor function in persons with high activity (90th percentile). By contrast, higher WMH burden remained associated with lower motor function in persons with average (50th percentile; estimate = −0.304, slope = −0.133) and low (10th percentile; estimate = −1.793, slope = −0.241) activity. Conclusions: Higher levels of physical activity may reduce the effect of WMH burden on motor function in healthy older adults. PMID:25762710

  13. Biomechanical evaluation of the Eco-Pick lift assist: A device designed to facilitate product selection tasks in distribution centers.

    PubMed

    Lavender, Steven A; Ko, Pei-Ling; Sommerich, Carolyn M

    2013-03-01

    Developing lift assist devices to aid workers performing case tasks in distribution centers has been challenging given the movement of workers through a distribution facility. The objective of this work was to biomechanically evaluate a lift assist that can be integrated with pallet jacks and thereby move through the facility with the workers. Twelve participants transferred 16.4 kg boxes from one pallet to another manually and using the Eco-Pick lift assist. Electromyographic (EMG) activities were measured bilaterally in the Bicep, Deltoid, Latissimus Dorsi, and Erector Spinae muscles. The analysis showed that the 90th percentile normalized EMG values were significantly reduced in 4 of the 8 muscles sampled when using the Eco-Pick. Likewise, the 50th percentile normalized EMG data were significantly reduced for the Erector Spinae, Latissimus Dorsi, and the Bicep muscles when using the assist. For some of the muscles the advantage of the Eco-Pick was dependent upon the initial lift height or the placement height. Overall, it appears that this evaluation of the Eco-Pick's efficacy indicates that the device has the potential to be an effective means of reducing worker exposure to risk factors associated with back and shoulder injuries experienced during manual palletizing tasks found in distribution centers. PMID:22884290

  14. Net Risk: A Risk Assessment of Long-Lasting Insecticide Bed Nets Used for Malaria Management

    PubMed Central

    Peterson, Robert K. D.; Barber, Loren M.; Schleier, Jerome J.

    2011-01-01

    Despite the demonstrated ability of bed nets that have been factory-impregnated with long-lasting insecticides (LLINs) to protect people from malaria and despite the ambitious plans for their widespread use, the health risks from the LLINs themselves have not been adequately investigated and reported in the peer-reviewed science literature. Here, we use a probabilistic risk assessment approach to estimate the risks to Africans from inhalation, dermal, and oral exposures to the newer LLINs with permethrin, α-cypermethrin, or deltamethrin as the insecticide active ingredient. We estimated exposures to LLINs using 17 age groups to incorporate different body weights and sleeping behaviors. Risk quotients (exposure divided by toxic threshold) at the 50th and 90th percentiles for non-cancer risks were < 1.0 for lifetime adjusted risk and all youth and adult age groups. Risk quotients for infants and toddlers (0–3 years) and child groups from 3 to 10 years were ≥ 1.0 for specific bed nets. PMID:21633033

  15. Effects of mop handle height on shoulder muscle activity and perceived exertion during floor mopping using a figure eight method

    PubMed Central

    WALLIUS, Mari-Anne; RISSANEN, Saara M.; BRAGGE, Timo; VARTIAINEN, Paavo; KARJALAINEN, Pasi A.; RÄSÄNEN, Kimmo; JÄRVELIN-PASANEN, Susanna

    2015-01-01

    The aim of this study was to investigate effects of mop handle height on electromyographic (EMG) activities of the shoulder muscles and perceived exertion for the shoulder area during floor mopping using a figure eight method. An experimental study with 13 cleaners was conducted using surface EMG and category ratio (CR-10) scale. EMG activity was recorded unilaterally from the upper trapezius, infraspinatus, anterior and middle deltoid muscles. Each subject performed four trials of mopping and each trial consisted of using a different mop handle height (mop adjustment at the level of shoulder, chin, nose and eye) in randomized order. EMG data were normalized to a percentage of maximal voluntary contraction (%MVC). The muscle activities were assessed by estimating the 10th, 50th and 90th percentiles of the amplitude probability distribution function (APDF) of the EMG signals and analysed by linear mixed model analysis. Results showed that shoulder muscle activity was significantly lower when the mop handle height was adjusted to shoulder level or chin level as compared to eye level. These findings were supported by subjective ratings of exertion. It seems that mop handle height adjustment between shoulder and chin level may be recommended as a basis for figure eight mopping. PMID:26423328

  16. Effects of mop handle height on shoulder muscle activity and perceived exertion during floor mopping using a figure eight method.

    PubMed

    Wallius, Mari-Anne; Rissanen, Saara M; Bragge, Timo; Vartiainen, Paavo; Karjalainen, Pasi A; Räsänen, Kimmo; Järvelin-Pasanen, Susanna

    2016-01-01

    The aim of this study was to investigate effects of mop handle height on electromyographic (EMG) activities of the shoulder muscles and perceived exertion for the shoulder area during floor mopping using a figure eight method. An experimental study with 13 cleaners was conducted using surface EMG and category ratio (CR-10) scale. EMG activity was recorded unilaterally from the upper trapezius, infraspinatus, anterior and middle deltoid muscles. Each subject performed four trials of mopping and each trial consisted of using a different mop handle height (mop adjustment at the level of shoulder, chin, nose and eye) in randomized order. EMG data were normalized to a percentage of maximal voluntary contraction (%MVC). The muscle activities were assessed by estimating the 10th, 50th and 90th percentiles of the amplitude probability distribution function (APDF) of the EMG signals and analysed by linear mixed model analysis. Results showed that shoulder muscle activity was significantly lower when the mop handle height was adjusted to shoulder level or chin level as compared to eye level. These findings were supported by subjective ratings of exertion. It seems that mop handle height adjustment between shoulder and chin level may be recommended as a basis for figure eight mopping. PMID:26423328

  17. Visibility trends in Tehran during 1958-2008

    NASA Astrophysics Data System (ADS)

    Sabetghadam, Samaneh; Ahmadi-Givi, Farhang; Golestani, Yahya

    2012-12-01

    Visibility, in the absence of certain weather conditions (e.g., fog and rain), is an excellent indicator of air quality because its impairment results from light scattering and absorption by atmospheric particles and gases. In this study, the historical airport visibility database is explored during the last five decades for the city of Tehran, Iran. Seasonal and long-term variations of the visibility are investigated using cumulative percentiles. The correlation of the long-term visibility trend with precipitation, fog and high relative humidity are also examined.The trends of visual range of the best, median, and worst visibilities at 10th, 50th and 90th percentiles of daily visibility data indicate an overall downward trend for all the percentiles. Results show a larger decrease in visibility for the Tehran metropolitan area than the sparsely populated and less polluted parts of the city. The largest trend in decreasing visibility is observed during winter time followed by spring, fall and summer. Decreasing trends in visibility occur for all stations and do not significantly depend on the special weather events.

  18. Development of Chinese reference man deformable surface phantom and its application to the influence of physique on electromagnetic dosimetry.

    PubMed

    Yu, D; Wang, M; Liu, Q

    2015-09-01

    A reference man is a theoretical individual that represents the average anatomical structure and physiological and metabolic features of a specific group of people and has been widely used in radiation safety research. With the help of an advantage in deformation, the present work proposed a Chinese reference man adult-male polygon-mesh surface phantom based on the Visible Chinese Human segment image dataset by surface rendering and deforming. To investigate the influence of physique on electromagnetic dosimetry in humans, a series of human phantoms with 10th, 50th and 90th body mass index and body circumference percentile physiques for Chinese adult males were further constructed by deforming the Chinese reference man surface phantom. All the surface phantoms were then voxelized to perform electromagnetic field simulation in a frequency range of 20 MHz to 3 GHz using the finite-difference time-domain method and evaluate the whole-body average and organ average specific absorption rate and the ratios of absorbed energy in skin, fat and muscle to the whole body. The results indicate thinner physique leads to higher WBSAR and the volume of subcutaneous fat, the penetration depth of the electromagnetic field in tissues and standing-wave occurrence may be the influence factors of physique on electromagnetic dosimetry. PMID:26301501

  19. Development of Chinese reference man deformable surface phantom and its application to the influence of physique on electromagnetic dosimetry

    NASA Astrophysics Data System (ADS)

    Yu, D.; Wang, M.; Liu, Q.

    2015-09-01

    A reference man is a theoretical individual that represents the average anatomical structure and physiological and metabolic features of a specific group of people and has been widely used in radiation safety research. With the help of an advantage in deformation, the present work proposed a Chinese reference man adult-male polygon-mesh surface phantom based on the Visible Chinese Human segment image dataset by surface rendering and deforming. To investigate the influence of physique on electromagnetic dosimetry in humans, a series of human phantoms with 10th, 50th and 90th body mass index and body circumference percentile physiques for Chinese adult males were further constructed by deforming the Chinese reference man surface phantom. All the surface phantoms were then voxelized to perform electromagnetic field simulation in a frequency range of 20 MHz to 3 GHz using the finite-difference time-domain method and evaluate the whole-body average and organ average specific absorption rate and the ratios of absorbed energy in skin, fat and muscle to the whole body. The results indicate thinner physique leads to higher WBSAR and the volume of subcutaneous fat, the penetration depth of the electromagnetic field in tissues and standing-wave occurrence may be the influence factors of physique on electromagnetic dosimetry.

  20. Validation of the global reference for fetal weight and birth weight percentiles.

    PubMed

    Badade, Anirudh B; Bhide, Amar; Satoskar, Purnima; Wadekar, Darshan

    2013-07-01

    The objective of this study was to evaluate whether the global reference curves adapted on the basis of WHO data for India and the Hadlock reference curves fit the population in India and to validate the reference curves. The data were retrieved retrospectively from the records of women registration for antenatal care at a charitable maternity hospital in Mumbai, India. All pregnancies were dated on CRL obtained before 14 weeks. Births before 34(th) week were excluded. The expected frequencies of birth weights below the 1(st), 5(th), 10(th), 50(th), 90(th), 95(th) and 99(th) centiles from three reference ranges were compared with observed frequencies. It was found that the WHO generic reference adapted to India significantly underpredicted the birth weights and that the Hadlock reference ranges significantly overpredicted the birth weights. The use of generic reference adapted to Sri Lanka showed a better fit to the observed data. We concluded that global reference curves adapted on the basis of WHO data for India and the Hadlock reference ranges do not fit all the population in India and the charts need validation. Reference charts modified on the basis of data for Sri Lankan population show a better fit to the observed data, and therefore are more appropriate for use in clinical practice in South India. PMID:24347860

  1. Growth and maturity status of elite British junior tennis players.

    PubMed

    Myburgh, Gillian K; Cumming, Sean P; Coelho E Silva, Manuel; Cooke, Karl; Malina, Robert M

    2016-10-01

    Growth and maturation impact the selection, development and progression of youth athletes. Individual differences in the growth and maturity may afford a performance advantage, clouding coaches and practitioners' perceptions regarding current ability and future potential. This may result in the exclusion of talented, yet less physically gifted athletes. Participants were 91 male (n = 47) and female (n = 44) elite British Junior tennis players, 8-17 years of age (12.5 ± 1.9 years). Height and body mass were measured and compared to growth charts; hand-wrist radiographs were taken. Skeletal age (SA) was estimated with the Fels method and contrasted to chronological age (CA). Mean height and body mass of individual players ranged between the 50th and 90th centiles for age and sex. Females were advanced in SA relative to CA (0.3-0.89 years.) from 8 years. Males were average to delayed in maturation from 8 to 12 years, but advanced in SA from 14 to 16 years (0.75-1.23 years). Individual differences in growth and maturation appear to contribute towards the selection of elite junior tennis players, with a bias towards males and females who are advanced in maturation and comparatively tall and heavy for their age. This has important implications for talent identification and development. PMID:26930031

  2. Major mutation events in structural genes of peste des petits ruminants virus through serial passages in vitro.

    PubMed

    Wu, Xiaodong; Liu, Fuxiao; Li, Lin; Zou, Yanli; Liu, Shan; Wang, Zhiliang

    2016-06-01

    Peste des petits ruminants (PPR) is an highly contagious disease of small ruminants, and caused by peste des petits ruminants virus (PPRV), a member of the genus Morbillivirus in the family Paramyxoviridae. The first outbreak of PPR in China was officially reported in July 2007, when a PPRV strain was successfully isolated from a sick goat in Tibet, followed by sequencing at a full-genome level (China/Tibet/Geg/07-30, GenBank: FJ905304.1). To date, this isolate has been virulently attenuated by more than 90 serial passages in Vero-Dog-SLAM cells at our laboratory. In this study, a total of nine strains by serial passages (namely the 10th, 20th, 30th, 40th, 50th, 60th, 70th, 80th, and 90th passages) were chosen for sequencing of six structural genes in PPRV. The sequence analysis showed that mutation rates in all viral genes were relatively low, and only a few identical mutations within certain genes were stably maintained after an earlier passage, perhaps indicating a predominance of mutants after such a passage. PMID:26995222

  3. Drought-Trigger Ground-Water Levels in Chester County, Pennsylvania, for the Period of Record Ending May 2006

    USGS Publications Warehouse

    Cinotto, Peter J.

    2007-01-01

    This report presents the results of a study by the U.S. Geological Survey (USGS), in cooperation with the Chester County Water Resources Authority (CCWRA), to update the drought-trigger water levels for the Chester County observation-well network. The Chester County observation-well network was established in 1973 through a cooperative agreement between the CCWRA and the USGS to monitor local ground-water levels and trends and to determine drought conditions. In 1990 and again in 1997, drought-warning and drought-emergency water-level triggers were determined for the majority of wells in the existing Chester County observation-well network of 23 wells. Since 1997, the Chester County observation-well network expanded to 29 wells, some of the original wells were destroyed, and additional monthly water-level observations were made to allow for better statistical relations. Because of these changes, new statistics for water-level triggers were required. For this study, 19 of the 29 wells in the observation-well network were used to compute drought-trigger water levels. An additional 'drought-watch water-level trigger' category was developed to make the Chester County drought-trigger water-level categories consistent with those implemented by the Pennsylvania Department of Environmental Protection (PaDEP). The three drought-trigger water-level categories, as defined by PaDEP are 1) 'drought watch' when at the 75th-percentile level; 2) 'drought warning' when at the 90th-percentile level; and 3) 'drought emergency' when at the 95th-percentile level. A revised methodology, resulting from longer periods of record representing ground-water and climatic conditions and changes in local water use, has resulted in some observed differences in drought-trigger water levels. A comparison of current drought-trigger water levels to those calculated in 1997 shows the largest mean annual change in percentile values was in northeastern Chester County. In this northeastern region, the

  4. Relationship between Urbanization and Cancer Incidence in Iran Using Quantile Regression.

    PubMed

    Momenyan, Somayeh; Sadeghifar, Majid; Sarvi, Fatemeh; Khodadost, Mahmoud; Mosavi-Jarrahi, Alireza; Ghaffari, Mohammad Ebrahim; Sekhavati, Eghbal

    2016-01-01

    Quantile regression is an efficient method for predicting and estimating the relationship between explanatory variables and percentile points of the response distribution, particularly for extreme percentiles of the distribution. To study the relationship between urbanization and cancer morbidity, we here applied quantile regression. This cross-sectional study was conducted for 9 cancers in 345 cities in 2007 in Iran. Data were obtained from the Ministry of Health and Medical Education and the relationship between urbanization and cancer morbidity was investigated using quantile regression and least square regression. Fitting models were compared using AIC criteria. R (3.0.1) software and the Quantreg package were used for statistical analysis. With the quantile regression model all percentiles for breast, colorectal, prostate, lung and pancreas cancers demonstrated increasing incidence rate with urbanization. The maximum increase for breast cancer was in the 90th percentile (β=0.13, p-value<0.001), for colorectal cancer was in the 75th percentile (β=0.048, p-value<0.001), for prostate cancer the 95th percentile (β=0.55, p-value<0.001), for lung cancer was in 95th percentile (β=0.52, p-value=0.006), for pancreas cancer was in 10th percentile (β=0.011, p-value<0.001). For gastric, esophageal and skin cancers, with increasing urbanization, the incidence rate was decreased. The maximum decrease for gastric cancer was in the 90th percentile(β=0.003, p-value<0.001), for esophageal cancer the 95th (β=0.04, p-value=0.4) and for skin cancer also the 95th (β=0.145, p-value=0.071). The AIC showed that for upper percentiles, the fitting of quantile regression was better than least square regression. According to the results of this study, the significant impact of urbanization on cancer morbidity requirs more effort and planning by policymakers and administrators in order to reduce risk factors such as pollution in urban areas and ensure proper nutrition

  5. High-density lipoprotein subfractions and carotid plaque: The Northern Manhattan Study

    PubMed Central

    Tiozzo, Eduard; Gardener, Hannah; Hudson, Barry I.; Dong, Chuanhui; Della-Morte, David; Crisby, Milita; Goldberg, Ronald B.; Elkind, Mitchell S.V.; Cheung, Ying Kuen; Wright, Clinton B.; Sacco, Ralph L.; Rundek, Tatjana

    2016-01-01

    Objective The objective of this cross-sectional analysis was to investigate the relation between two major high-density lipoprotein cholesterol (HDL-C) subfractions (HDL2-C and HDL3-C) and carotid plaque in a population based cohort. Methods We evaluated 988 stroke-free participants (mean age 66±8 years; 40% men; 66% Hispanic and 34% Non-Hispanic) with available data on HDL subfractions using precipitation method and carotid plaque area and thickness assessed by a high-resolution 2D ultrasound. The associations between HDL-C subfractions and plaque measurements were analyzed by quantile regression. Results Plaque was present in 56% of the study population. Among those with plaque, the mean±SD plaque area was 19.40±20.46 mm2 and thickness 2.30±4.45 mm. The mean±SD total HDL-C was 46±14 mg/dl, HDL2-C 14±8 mg/dl, and HDL3-C 32±8 mg/dl. After adjusting for demographics and vascular risk factors, there was an inverse association between HDL3-C and plaque area (per mg/dl: beta= −0.26 at the 75th percentile, p=0.001 and beta= −0.32 at the 90th percentile, p=0.02). A positive association was observed between HDL2-C and plaque thickness (per mg/dl; beta= 0.02 at the 90% percentile, p=0.003). HDL-C was associated with plaque area (per mg/dl: beta= −0.18 at the 90th percentile, p=0.01), but only among Hispanics. Conclusion In our cohort we observed an inverse association between HDL3-C and plaque area and a positive association between HDL2-C and plaque thickness. HDL-C subfractions may have different contributions to the risk of vascular disease. More studies are needed to fully elucidate HDL-C anti-atherosclerotic functions in order to improve HDL-based treatments in prevention of vascular disease and stroke. PMID:25240111

  6. Single blood-Hg samples can result in exposure misclassification: temporal monitoring within the Japanese community (United States)

    PubMed Central

    2012-01-01

    Background The most prominent non-occupational source of exposure to methylmercury is the consumption of fish. In this study we examine a fish consuming population to determine the extent of temporal exposure and investigate the extent to which single time estimates of methylmercury exposure based on blood-Hg concentration can provide reliable estimates of longer-term average exposure. Methods Blood-mercury levels were obtained from a portion of the Arsenic Mercury Intake Biometric Study (AMIBS) cohort. Specifically, 56 Japanese women residing in the Puget Sound area of Washington State, US were sampled on three occasions across a one-year period. Results An average of 135 days separated samples, with mean blood-mercury levels for the visits being 5.1, 6.6 and 5.0 μg/l and geometric means being 2.7, 4.5 and 3.1 μg/l. The blood-mercury levels in this group exceed national averages with geometric means for two of the visits being between the 90th and 95th percentiles of nationally observed levels and the lowest geometric mean being between the 75th and 90th percentile. Group means were not significantly different across sampling periods suggesting that exposure of combined subjects remained relatively constant. Comparing intra-individual results over time did not reveal a strong correlation among visits (r = 0.19, 0.50, 0.63 between 1st and 2nd, 2nd and 3rd, and 1st and 3rd sample results, respectively). In comparing blood-mercury levels across two sampling interval combinations (1st and 2nd, 2nd and 3rd, and 1st and 3rd visits, respectively), 58% (n = 34), 53% (n = 31) and 29% (n = 17) of the individuals had at least a 100% difference in blood-Hg levels. Conclusions Point estimates of blood-mercury, when compared with three sample averages, may not reflect temporal variability and individual exposures estimated on the basis of single blood samples should be treated with caution as indicators of long-term exposure. Reliance on single blood

  7. A resolution recognizing the 75th Anniversary of the Welfare Program of The Church of Jesus Christ of Latter-day Saints and the significant impact of the Welfare Program in the United States and throughout the world in helping people in need.

    THOMAS, 112th Congress

    Sen. Hatch, Orrin G. [R-UT

    2011-11-15

    11/15/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S7584-7585; text as passed Senate: CR S7584-7585; text of measure as introduced: CR S7454-7455) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  8. S.Res.323 — 112th Congress (2011-2012) A resolution recognizing the 75th Anniversary of the Welfare Program of The Church of Jesus Christ of Latter-day Saints and the significant impact of the Welfare Program in the United States and...

    THOMAS, 112th Congress

    Sen. Hatch, Orrin G. [R-UT

    2011-11-15

    11/15/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S7584-7585; text as passed Senate: CR S7584-7585; text of measure as introduced: CR S7454-7455) (All Actions)

  9. Hybrid computational phantoms of the 15-year male and female adolescent: Applications to CT organ dosimetry for patients of variable morphometry

    PubMed Central

    Lee, Choonsik; Lodwick, Daniel; Williams, Jonathan L.; Bolch, Wesley E.

    2008-01-01

    female phantoms were further developed from the 50th percentile phantoms through adjustments in the body contour to match the total body masses given in CDC pediatric growth curves. The resulting six NURBS phantoms, male and female phantoms representing their 10th, 50th, and 90th weight percentiles, were used to investigate the influence of body fat distributions on internal organ doses following CT imaging. The phantoms were exposed to multislice chest and abdomen helical CT scans, and in-field organ absorbed doses were calculated. The results demonstrated that the use of traditional stylized phantoms yielded organ dose estimates that deviate from those given by the UF reference hybrid phantoms by up to a factor of 2. The study also showed that use of reference, or 50th percentile, phantoms to assess organ doses in underweight 15-year-old children would not lead to significant organ dose errors (typically less than 10%). However, more significant errors were noted (up to ∼30%) when reference phantoms are used to represent overweight children in CT imaging dosimetry. These errors are expected to only further increase as one considers CT organ doses in overweight and obese individuals of the adult patient population, thus emphasizing the advantages of patient-sculptable phantom technology. PMID:18649470

  10. Hybrid computational phantoms of the 15-year male and female adolescent: Applications to CT organ dosimetry for patients of variable morphometry

    SciTech Connect

    Lee, Choonsik; Lodwick, Daniel; Williams, Jonathan L.; Bolch, Wesley E.

    2008-06-15

    female phantoms were further developed from the 50th percentile phantoms through adjustments in the body contour to match the total body masses given in CDC pediatric growth curves. The resulting six NURBS phantoms, male and female phantoms representing their 10th, 50th, and 90th weight percentiles, were used to investigate the influence of body fat distributions on internal organ doses following CT imaging. The phantoms were exposed to multislice chest and abdomen helical CT scans, and in-field organ absorbed doses were calculated. The results demonstrated that the use of traditional stylized phantoms yielded organ dose estimates that deviate from those given by the UF reference hybrid phantoms by up to a factor of 2. The study also showed that use of reference, or 50th percentile, phantoms to assess organ doses in underweight 15-year-old children would not lead to significant organ dose errors (typically less than 10%). However, more significant errors were noted (up to {approx}30%) when reference phantoms are used to represent overweight children in CT imaging dosimetry. These errors are expected to only further increase as one considers CT organ doses in overweight and obese individuals of the adult patient population, thus emphasizing the advantages of patient-sculptable phantom technology.

  11. Total Hemi-overgrowth in Pigmentary Mosaicism of the (Hypomelanosis of) Ito Type

    PubMed Central

    Pavone, Vito; Signorelli, Salvatore Santo; Praticò, Andrea Domenico; Corsello, Giovanni; Savasta, Salvatore; Falsaperla, Raffaele; Pavone, Piero; Sessa, Giuseppe; BA, Martino Ruggieri

    2016-01-01

    Abstract Pigmentary mosaicism of the (hypomelanosis of) Ito type is an umbrella term, which includes phenotypes characterized by mosaic hypopigmentation in the form of streaks, whorls, patchy, or more bizarre skin configurations (running along the lines of Blaschko): these cutaneous patterns can manifest as an isolated skin disorder (pigmentary mosaicism of the Ito type) or as a complex malformation syndrome in association with extracutaneous anomalies (most often of the musculoskeletal and/or nervous systems) (hypomelanosis of Ito). Affected individuals are anecdotally reported to have also partial or total body hemi-overgrowth (HOG), which often causes moderate to severe complications. We studied the occurrence and features of HOG in the 114 children and adults with mosaic pigmentary disorders of the Ito type diagnosed and followed up (from 2 to 22 years; average follow-up 16 years) at our Institutions. Eight patients (5 M, 3 F; aged 4 to 25 years; median age 16 years) out of the 114 analyzed (7%) fulfilled the criteria for unilateral HOG, with differences in diameter ranging from 0.4 to 4.0 cm (upper limbs) and 1.0 to 9.0 cm (lower limbs). Moreover, among these 8 patients, 5/8 filled in the 75th to 90th percentile for height; 6/8 had associated kyphoscoliosis; and 5/8 showed cognitive delays. No tumour complications were recorded. Overall, 6/8 HOG patients presented with additional (extracutaneous) syndromic manifestations, apart from the HOG (ie, with a clinical phenotype of hypomelanosis of Ito). The present study, which includes children and adults with the longest follow-up so far recorded, confirms the association between pigmentary mosaicism of the Ito type and HOG lowering previous estimates (7% vs 16%) for HOG in the context of mosaic hypopigmentation. A careful examination, looking at subtle to moderate asymmetries and associated complications within the spectrum of these mosaic pigmentary disorders, is recommended. PMID:26962770

  12. Particulate Organic Matter Affects Soil Nitrogen Mineralization under Two Crop Rotation Systems.

    PubMed

    Bu, Rongyan; Lu, Jianwei; Ren, Tao; Liu, Bo; Li, Xiaokun; Cong, Rihuan

    2015-01-01

    Changes in the quantity and/or quality of soil labile organic matter between and after different types of cultivation system could play a dominant role in soil nitrogen (N) mineralization. The quantity and quality of particulate organic matter (POM) and potentially mineralizable-N (PMN) contents were measured in soils from 16 paired rice-rapeseed (RR)/cotton-rapeseed (CR) rotations sites in Hubei province, central China. Then four paired soils encompassing low (10th percentile), intermediate (25th and 75th percentiles), and high (90th percentile) levels of soil PMN were selected to further study the effects of POM on soil N mineralization by quantifying the net N mineralization in original soils and soils from which POM was removed. Both soil POM carbon (POM-C) and N (POM-N) contents were 45.8% and 55.8% higher under the RR rotation compared to the CR rotation, respectively. The PMN contents were highly correlated with the POM contents. The PMN and microbial biomass N (MBN) contents concurrently and significantly decreased when POM was removed. The reduction rate of PMN was positively correlated with changes in MBN after the removal of POM. The reduction rates of PMN and MBN after POM removal are lower under RR rotations (38.0% and 16.3%, respectively) than CR rotations (45.6% and 19.5%, respectively). Furthermore, infrared spectroscopy indicated that compounds with low-bioavailability accumulated (e.g., aromatic recalcitrant materials) in the soil POM fraction under the RR rotation but not under the CR rotation. The results of the present study demonstrated that POM plays a vital role in soil N mineralization under different rotation systems. The discrepancy between POM content and composition resulting from different crop rotation systems caused differences in N mineralization in soils. PMID:26647157

  13. Evaluation of CMIP5 continental precipitation simulations relative to satellite-based gauge-adjusted observations

    SciTech Connect

    Mehran, Ali; AghaKouchak, Amir; Phillips, Thomas J.

    2014-02-25

    Numerous studies have emphasized that climate simulations are subject to various biases and uncertainties. The objective of this study is to cross-validate 34 Coupled Model Intercomparison Project Phase 5 (CMIP5) historical simulations of precipitation against the Global Precipitation Climatology Project (GPCP) data, quantifying model pattern discrepancies and biases for both entire data distributions and their upper tails. The results of the Volumetric Hit Index (VHI) analysis of the total monthly precipitation amounts show that most CMIP5 simulations are in good agreement with GPCP patterns in many areas, but that their replication of observed precipitation over arid regions and certain sub-continental regions (e.g., northern Eurasia, eastern Russia, central Australia) is problematical. Overall, the VHI of the multi-model ensemble mean and median also are superior to that of the individual CMIP5 models. However, at high quantiles of reference data (e.g., the 75th and 90th percentiles), all climate models display low skill in simulating precipitation, except over North America, the Amazon, and central Africa. Analyses of total bias (B) in CMIP5 simulations reveal that most models overestimate precipitation over regions of complex topography (e.g. western North and South America and southern Africa and Asia), while underestimating it over arid regions. Also, while most climate model simulations show low biases over Europe, inter-model variations in bias over Australia and Amazonia are considerable. The Quantile Bias (QB) analyses indicate that CMIP5 simulations are even more biased at high quantiles of precipitation. Lastly, we found that a simple mean-field bias removal improves the overall B and VHI values, but does not make a significant improvement in these model performance metrics at high quantiles of precipitation.

  14. Particulate Organic Matter Affects Soil Nitrogen Mineralization under Two Crop Rotation Systems

    PubMed Central

    Bu, Rongyan; Lu, Jianwei; Ren, Tao; Liu, Bo; Li, Xiaokun; Cong, Rihuan

    2015-01-01

    Changes in the quantity and/or quality of soil labile organic matter between and after different types of cultivation system could play a dominant role in soil nitrogen (N) mineralization. The quantity and quality of particulate organic matter (POM) and potentially mineralizable-N (PMN) contents were measured in soils from 16 paired rice-rapeseed (RR)/cotton-rapeseed (CR) rotations sites in Hubei province, central China. Then four paired soils encompassing low (10th percentile), intermediate (25th and 75th percentiles), and high (90th percentile) levels of soil PMN were selected to further study the effects of POM on soil N mineralization by quantifying the net N mineralization in original soils and soils from which POM was removed. Both soil POM carbon (POM-C) and N (POM-N) contents were 45.8% and 55.8% higher under the RR rotation compared to the CR rotation, respectively. The PMN contents were highly correlated with the POM contents. The PMN and microbial biomass N (MBN) contents concurrently and significantly decreased when POM was removed. The reduction rate of PMN was positively correlated with changes in MBN after the removal of POM. The reduction rates of PMN and MBN after POM removal are lower under RR rotations (38.0% and 16.3%, respectively) than CR rotations (45.6% and 19.5%, respectively). Furthermore, infrared spectroscopy indicated that compounds with low-bioavailability accumulated (e.g., aromatic recalcitrant materials) in the soil POM fraction under the RR rotation but not under the CR rotation. The results of the present study demonstrated that POM plays a vital role in soil N mineralization under different rotation systems. The discrepancy between POM content and composition resulting from different crop rotation systems caused differences in N mineralization in soils. PMID:26647157

  15. Blood Lead Levels and children’s Behavioral and Emotional Problems: A Cohort Study

    PubMed Central

    Liu, Jianghong; Liu, Xianchen; Wang, Wei; McCauley, Linda; Pinto-Martin, Jennifer; Wang, Yingjie; Li, Linda; Yan, Chonghuai; Rogan, Walter J.

    2014-01-01

    Importance The association between lead exposure and children’s IQ has been well studied, but few studies have examined the effects of blood lead on children’s behavior. Objective This study examined the association between blood lead concentrations and behavioral problems in a community sample of Chinese preschool children with a mean blood lead level <10 µg/dL. Design Prospective cohort study. Setting Four elementary schools in Jintan City, Jiangsu Province of China. Participants Participants were 1341 children at ages 3–5 years. Main Outcome Measures Blood lead concentration was measured at ages 3–5 years. Behavioral problems were assessed using Chinese versions of the Child Behavior Checklist and Teacher Report Form when children at age 6 years. Results Mean blood lead concentration was 6.4 µg/dL (SD=2.6), with 75th and 90th percentiles being 7.7 and 9.4 µg/dL respectively. General linear modeling showed significant associations between blood lead concentrations and increased scores for teacher reported behavioral problems. One µg/dL increase of blood lead concentration resulted in a 0.32, 0.25 and 0.30 increase of behavior scores on emotional reactivity, anxiety/depressed and pervasive developmental problems, respectively (p <0.05), while adjusting for parental and child variables,. Spline modeling showed that teacher-reported behavior scores increased with blood lead concentration, particular for older girls. Conclusions and Relevance Blood lead concentrations, even at mean levels of 6.4 µg/dL, were associated with increased risk of behavioral problems in Chinese preschool children, including internalizing and pervasive developmental problems. This association showed different patterns depending on age and gender. PMID:25090293

  16. Evaluation of CMIP5 continental precipitation simulations relative to satellite-based gauge-adjusted observations

    NASA Astrophysics Data System (ADS)

    Mehran, A.; AghaKouchak, A.; Phillips, T. J.

    2014-02-01

    The objective of this study is to cross-validate 34 Coupled Model Intercomparison Project Phase 5 (CMIP5) historical simulations of precipitation against the Global Precipitation Climatology Project (GPCP) data, quantifying model pattern discrepancies, and biases for both entire distributions and their upper tails. The results of the volumetric hit index (VHI) analysis of the total monthly precipitation amounts show that most CMIP5 simulations are in good agreement with GPCP patterns in many areas but that their replication of observed precipitation over arid regions and certain subcontinental regions (e.g., northern Eurasia, eastern Russia, and central Australia) is problematical. Overall, the VHI of the multimodel ensemble mean and median also are superior to that of the individual CMIP5 models. However, at high quantiles of reference data (75th and 90th percentiles), all climate models display low skill in simulating precipitation, except over North America, the Amazon, and Central Africa. Analyses of total bias (B) in CMIP5 simulations reveal that most models overestimate precipitation over regions of complex topography (e.g., western North and South America and southern Africa and Asia), while underestimating it over arid regions. Also, while most climate model simulations show low biases over Europe, intermodel variations in bias over Australia and Amazonia are considerable. The quantile bias analyses indicate that CMIP5 simulations are even more biased at high quantiles of precipitation. It is found that a simple mean field bias removal improves the overall B and VHI values but does not make a significant improvement at high quantiles of precipitation.

  17. Reference values for heavy metals in soils of the Brazilian agricultural frontier in Southwestern Amazônia.

    PubMed

    dos Santos, Sabrina Novaes; Alleoni, Luís Reynaldo Ferracciú

    2013-07-01

    Guideline values are used to identify polluted or contaminated areas based on background values. Brazilian law establishes three guideline values for pollutants: a quality reference value (QRV), a prevention value, and an intervention value. Reference values refer to the natural concentration of an element or a substance in soils that have not been modified by anthropogenic impacts. These values inform assessments of soil quality and are used to establish maximum permissible limits. The objective of this study was to determine the natural levels and reference values for Cd, Co, Cr, Cu, Ni, Pb, and Zn in samples from the surface layer (0-20 cm) of 19 representative soils of the states of Mato Grosso and Rondônia, on Brazil's agricultural frontier. Pseudo-total metal concentrations were obtained following microwave-assisted digestion using the aqua regia and EPA3051 methods. QRVs were calculated for each element as the 75th and 90th percentiles of the frequency distribution of the data. Natural levels of heavy metals in the soil samples followed the order: Cr > Zn > Cu > Co > Pb > Ni > and Cd (aqua regia) and Cr > Co > Cu > Pb > Zn > Ni > Cd (EPA3051). These values are generally lower than those reported in the Brazilian and international literature, which highlights the importance of establishing reference values for each state or for each soil type, taking into account the geomorphological, pedological, and geological diversity of the region under study. PMID:23138418

  18. Total Hemi-overgrowth in Pigmentary Mosaicism of the (Hypomelanosis of) Ito Type: Eight Case Reports.

    PubMed

    Pavone, Vito; Signorelli, Salvatore Santo; Praticò, Andrea Domenico; Corsello, Giovanni; Savasta, Salvatore; Falsaperla, Raffaele; Pavone, Piero; Sessa, Giuseppe; Ruggieri, Martino; Ba, Martino Ruggieri

    2016-03-01

    Pigmentary mosaicism of the (hypomelanosis of) Ito type is an umbrella term, which includes phenotypes characterized by mosaic hypopigmentation in the form of streaks, whorls, patchy, or more bizarre skin configurations (running along the lines of Blaschko): these cutaneous patterns can manifest as an isolated skin disorder (pigmentary mosaicism of the Ito type) or as a complex malformation syndrome in association with extracutaneous anomalies (most often of the musculoskeletal and/or nervous systems) (hypomelanosis of Ito). Affected individuals are anecdotally reported to have also partial or total body hemi-overgrowth (HOG), which often causes moderate to severe complications.We studied the occurrence and features of HOG in the 114 children and adults with mosaic pigmentary disorders of the Ito type diagnosed and followed up (from 2 to 22 years; average follow-up 16 years) at our Institutions.Eight patients (5 M, 3 F; aged 4 to 25 years; median age 16 years) out of the 114 analyzed (7%) fulfilled the criteria for unilateral HOG, with differences in diameter ranging from 0.4 to 4.0 cm (upper limbs) and 1.0 to 9.0 cm (lower limbs). Moreover, among these 8 patients, 5/8 filled in the 75th to 90th percentile for height; 6/8 had associated kyphoscoliosis; and 5/8 showed cognitive delays. No tumour complications were recorded. Overall, 6/8 HOG patients presented with additional (extracutaneous) syndromic manifestations, apart from the HOG (ie, with a clinical phenotype of hypomelanosis of Ito).The present study, which includes children and adults with the longest follow-up so far recorded, confirms the association between pigmentary mosaicism of the Ito type and HOG lowering previous estimates (7% vs 16%) for HOG in the context of mosaic hypopigmentation. A careful examination, looking at subtle to moderate asymmetries and associated complications within the spectrum of these mosaic pigmentary disorders, is recommended. PMID:26962770

  19. Effects of weighting schemes on the identification of wildlife corridors generated with least-cost methods.

    PubMed

    Parks, Sean A; McKelvey, Kevin S; Schwartz, Michael K

    2013-02-01

    The importance of movement corridors for maintaining connectivity within metapopulations of wild animals is a cornerstone of conservation. One common approach for determining corridor locations is least-cost corridor (LCC) modeling, which uses algorithms within a geographic information system to search for routes with the lowest cumulative resistance between target locations on a landscape. However, the presentation of multiple LCCs that connect multiple locations generally assumes all corridors contribute equally to connectivity, regardless of the likelihood that animals will use them. Thus, LCCs may overemphasize seldom-used longer routes and underemphasize more frequently used shorter routes. We hypothesize that, depending on conservation objectives and available biological information, weighting individual corridors on the basis of species-specific movement, dispersal, or gene flow data may better identify effective corridors. We tested whether locations of key connectivity areas, defined as the highest 75th and 90th percentile cumulative weighted value of approximately 155,000 corridors, shift under different weighting scenarios. In addition, we quantified the amount and location of private land that intersect key connectivity areas under each weighting scheme. Some areas that appeared well connected when analyzed with unweighted corridors exhibited much less connectivity compared with weighting schemes that discount corridors with large effective distances. Furthermore, the amount and location of key connectivity areas that intersected private land varied among weighting schemes. We believe biological assumptions and conservation objectives should be explicitly incorporated to weight corridors when assessing landscape connectivity. These results are highly relevant to conservation planning because on the basis of recent interest by government agencies and nongovernmental organizations in maintaining and enhancing wildlife corridors, connectivity will likely

  20. The effect of ambient temperature on diabetes mortality in China: A multi-city time series study.

    PubMed

    Yang, Jun; Yin, Peng; Zhou, Maigeng; Ou, Chun-Quan; Li, Mengmeng; Liu, Yunning; Gao, Jinghong; Chen, Bin; Liu, Jiangmei; Bai, Li; Liu, Qiyong

    2016-02-01

    Few multi-city studies have been conducted to investigate the acute health effects of low and high temperatures on diabetes mortality worldwide. We aimed to examine effects of ambient temperatures on city-/gender-/age-/education-specific diabetes mortality in nine Chinese cities using a two-stage analysis. Distributed lag non-linear model was first applied to estimate the city-specific non-linear and delayed effects of temperatures on diabetes mortality. Pooled effects of temperatures on diabetes mortality were then obtained using meta-analysis, based on restricted maximum likelihood. We found that heat effects were generally acute and followed by a period of mortality displacement, while cold effects could last for over two weeks. The pooled relative risks of extreme high (99th percentile of temperature) and high temperature (90th percentile of temperature) were 1.29 (95%CI: 1.11-1.47) and 1.11 (1.03-1.19) over lag 0-21 days, compared with the 75th percentile of temperature. In contrast, the pooled relative risks over lag 0-21 days were 1.44 (1.25-1.66) for extreme low (1st percentile of temperature) and 1.20 (1.12-1.30) for low temperature (10th percentile of temperature), compared to 25th percentile of temperature. The estimate of heat effects was relatively higher among females than that among males, with opposite trend for cold effects, and the estimates of heat and cold effects were particularly higher among the elderly and those with low education, although the differences between these subgroups were not statistically significant (P>0.05). These findings have important public health implications for protecting diabetes patients from adverse ambient temperatures. PMID:26580729

  1. Will CMIP5 GCMs reduce uncertainty in hydrological projections?

    NASA Astrophysics Data System (ADS)

    Teng, J.; Chiew, F. H.; Vaze, J.

    2012-12-01

    left to right, 10th, 50th and 90th percentile estimates of percentage change in mean annual runoff derived from CMIP5 and CMIP3 GCMs. Percentage change in mean annual runoff for six regions derived from CMIP5 and CMIP3 GCMs.

  2. Ambient quality of ground water in the vicinity of Naval Submarine Base Bangor, Kitsap County, Washington, 1995

    USGS Publications Warehouse

    Greene, Karen E.

    1997-01-01

    A study of the ambient ground-water quality in the vicinity of Naval Submarine Base (SUBASE) Bangor was conducted to provide the U.S. Navywith background levels of selected constituents.The Navy needs this information to plan and manage cleanup activities on the base. DuringMarch and April 1995, 136 water-supply wells were sampled for common ions, trace elements, and organic compounds; not all wells were sampled for all constituents. Man-made organic compounds were detected in only two of fifty wells, and the sources of these organic compounds were attributed to activities in the immediate vicinities of these off- base wells. Drinking water standards for trichloroethylene, iron, and manganese were exceeded in one of these wells, which was probablycontaminated by an old local (off-base) dump. Ground water from wells open to the following hydrogeologic units (in order from shallow to deep) was investigated: the Vashon till confining unit (Qvt, three wells); the Vashon aquifer (Qva, 54 wells); the Upper confining unit (QC1, 16 wells); the Permeable interbeds within QC1 (QC1pi, 34 wells); and the Sea-level aquifer (QA1, 29 wells).The 50th and 90th percentile ambient background levels of 35 inorganic constituents were determined for each hydrogeologic unit. At least tenmeasurements were required for a constituent in each hydro- geologic unit for determination of ambient background levels, and data for three wellsdetermined to be affected by localized activities were excluded from these analyses. The only drinking water standards exceeded by ambient background levels were secondary maximum contaminant levels for iron (300 micrograms per liter), in QC1 and QC1pi, and manganese (50 micrograms per liter), in all of the units. The 90th percentile values for arsenic in QC1pi, QA1, and for the entire study area are above 5 micrograms per liter, the Model Toxics Control Act Method A value for protecting drinking water, but well below the maximum contaminant level of 50

  3. Extent of areal inundation of riverine wetlands along Cypress Creek and the Peace, Alafia, North Prong Alafia, and South Prong Alafia Rivers, west-central Florida

    USGS Publications Warehouse

    Lewelling, B.R.

    2003-01-01

    Riverine and palustrine system wetlands are a major ecological component of river basins in west-central Florida. Healthy wetlands are dependent upon the frequency and duration of periodic flooding or inundation. This report assesses the extent, area, depth, frequency, and duration of periodic flooding and the effects of potential surface-water withdrawals on the wetlands along Cypress Creek and the Peace, Alafia, North Prong Alafia, and South Prong Alafia Rivers. Results of the study were derived from step-backwater analysis performed at each of the rivers using the U.S. Army Corps of Engineers Hydrologic Engineering Center-River Analysis System (HEC-RAS) one-dimensional model. The step-backwater analysis was performed using selected daily mean discharges at the 10th, 50th, 70th, 80th, 90th, 98th, 99.5th, and 99.9th percentiles to compute extent of areal inundation, area of inundation, and hydraulic depth to assess the net reduction of areal inundation if 10 percent of the total river flow were diverted for potential withdrawals. The extent of areal inundation is determined by cross-sectional topography and the degree to which the channel is incised. Areal inundation occurs along the broad, low relief of the Cypress Creek floodplain during all selected discharge percentiles. However, areal inundation of the Peace and Alafia Rivers floodplains, which generally have deeply incised channels, occurs at or above discharges at the 80th percentile. The greatest area of inundation along the three rivers generally occurs between the 90th and 98th percentile discharges. The decrease in inundated area resulting from a potential 10-percent withdrawal in discharge ranged as follows: Cypress Creek, 22 to 395 acres (1.7 to 8.4 percent); Peace River, 17 to 1,900 acres (2.1 to 13.6 percent); Alafia River, 1 to 90 acres (1 to 19.6 percent); North Prong Alafia River, 1 to 46 acres (0.7 to 23.4 percent); and South Prong Alafia River, 1 to 75 acres (1.5 to 13.4 percent).

  4. Estimated water use and availability in the lower Blackstone River basin, northern Rhode Island and south-central Massachusetts, 1995-99

    USGS Publications Warehouse

    Barolw, Lora K.

    2003-01-01

    flow, an estimated median rate of 50.5 Mgal/d of water was available for the basin during August, the lowest base-flow month. In addition, basin-wide water-availability estimates were calculated with and without streamflow criteria for each month of the low-flow period at the 75th, 50th, and 25th percentiles of base flow. These water availability estimates ranged from 42.3 to 181.7 Mgal/d in June; 20.2 to 96.7 Mgal/d in July; 20.2 to 85.4 Mgal/d in August, and 20.2 to 97.5 Mgal/d in September. Base flow was less than the Aquatic Base Flow (ABF), minimum flow considered adequate to protect aquatic fauna, from July through September at the 25th percentile and in August and September at the 50th percentile. A basin-stress ratio, which is equal to total withdrawals divided by water availability, was also calculated. The basin-stress ratio for August at the 50th percentile of base flow minus the 7Q10 was 0.68 for the study area. For individual subbasins, the ratio ranged from 0.13 in the Chepachet River subbasin to 0.95 in the Abbot Run subbasin. In addition, basin-stress ratios with and without streamflow criteria for all four months of the low-flow period were calculated at the 75th, 50th, and 25th percentiles of base flow. These values ranged from 0.19 to 0.83 in June, 0.36 to 1.50 in July, 0.40 to 1.14 in August, and 0.31 to 0.78 in September. Ratios could not be calculated by using the ABF at the 50th and 25th percentiles in August and September because the estimated base flow was less than the ABF. The depletion of the Blackstone River flows by Cumberland Water Department Manville well no. 1 in Rhode Island was estimated with the computer program STRMDEPL and specified daily pumping rates. STRMDEPL uses analytical solutions to calculate time-varying rates of streamflow depletion caused by pumping at wells. Results show that streamflow depletions were about 97 percent of average daily pumping rates for 1995 through 1999. Relative streamflow depletions for

  5. Management of groundwater in farmed pond area using risk-based regulation.

    PubMed

    Huang, Jun-Ying; Liao, Chiao-Miao; Lin, Kao-Hung; Lee, Cheng-Haw

    2014-09-01

    Blackfoot disease (BFD) had occurred seriously in the Yichu, Hsuehchia, Putai, and Peimen townships of Chia-Nan District of Taiwan in the early days. These four townships are the districts of fishpond cultivation domestically in Taiwan. Groundwater becomes the main water supply because of short income in surface water. The problems of over pumping in groundwater may not only result in land subsidence and seawater intrusion but also be harmful to the health of human giving rise to the bioaccumulation via food chain in groundwater with arsenic (As). This research uses sequential indicator simulation (SIS) to characterize the spatial arsenic distribution in groundwater in the four townships. Risk assessment is applied to explore the dilution ratio (DR) of groundwater utilization, which is defined as the ratio showing the volume of groundwater utilization compared to pond water, for fish farming in the range of target cancer risk (TR) especially on the magnitude of 10(-4)~10(-6). Our study results reveal that the 50th percentile of groundwater DRs served as a regulation standard can be used to perform fish farm groundwater management for a TR of 10(-6). For a TR of 5 × 10(-6), we suggest using the 75th percentile of DR for groundwater management. For a TR of 10(-5), we suggest using the 95th percentile of the DR standard for performing groundwater management in fish farm areas. For the TR of exceeding 5 × 10(-5), we do not suggest establishing groundwater management standards under these risk standards. Based on the research results, we suggest that establishing a TR at 10(-5) and using the 95th percentile of DR are best for groundwater management in fish farm areas. PMID:24869949

  6. Development of a quantitative food frequency questionnaire for Brazilian patients with type 2 diabetes

    PubMed Central

    2013-01-01

    Background To investigate the association between dietary components and development of chronic diabetic complications, the dietary evaluation should include a long period, months or years. The present manuscript aims to develop a quantitative food frequency questionnaire (FFQ) and a portfolio with food photos to assess the usual intake pattern of Brazilian patients with type 2 diabetes to be used in future studies. Methods Dietary data using 3-day weighed diet records (WDR) from 188 outpatients with type 2 diabetes were used to construct the list of usually consumed foods. Foods were initially clustered into eight groups: “cereals, tubers, roots, and derivatives”; “vegetables and legumes”; “fruits”; “beans”; “meat and eggs”; “milk and dairy products”; “oils and fats”, and “sugars and sweets”. The frequency of food intake and the relative contribution of each food item to the total energy and nutrient intakes were calculated. Portion sizes were determined according to the 25th, 50th, 75th, and 95th percentiles of intake for each food item. Results A total of 62 food items were selected based on the 3-day WDR and another 27 foods or how they are prepared and nine beverages were included after the expert examination. Also, a portfolio with food photos of each included food item and portion sizes was made to assist the patients in identifying the consumed portion. Conclusions We developed a practical quantitative FFQ and portfolio with photos of 98 food items covering those most commonly consumed in the past 12 months, to assess the usual diet pattern of patients with type 2 diabetes in Southern Brazil. PMID:23938026

  7. An Administrative Claims Model for Profiling Hospital 30-Day Mortality Rates for Pneumonia Patients

    PubMed Central

    Bratzler, Dale W.; Normand, Sharon-Lise T.; Wang, Yun; O'Donnell, Walter J.; Metersky, Mark; Han, Lein F.; Rapp, Michael T.; Krumholz, Harlan M.

    2011-01-01

    Background Outcome measures for patients hospitalized with pneumonia may complement process measures in characterizing quality of care. We sought to develop and validate a hierarchical regression model using Medicare claims data that produces hospital-level, risk-standardized 30-day mortality rates useful for public reporting for patients hospitalized with pneumonia. Methodology/Principal Findings Retrospective study of fee-for-service Medicare beneficiaries age 66 years and older with a principal discharge diagnosis of pneumonia. Candidate risk-adjustment variables included patient demographics, administrative diagnosis codes from the index hospitalization, and all inpatient and outpatient encounters from the year before admission. The model derivation cohort included 224,608 pneumonia cases admitted to 4,664 hospitals in 2000, and validation cohorts included cases from each of years 1998–2003. We compared model-derived state-level standardized mortality estimates with medical record-derived state-level standardized mortality estimates using data from the Medicare National Pneumonia Project on 50,858 patients hospitalized from 1998–2001. The final model included 31 variables and had an area under the Receiver Operating Characteristic curve of 0.72. In each administrative claims validation cohort, model fit was similar to the derivation cohort. The distribution of standardized mortality rates among hospitals ranged from 13.0% to 23.7%, with 25th, 50th, and 75th percentiles of 16.5%, 17.4%, and 18.3%, respectively. Comparing model-derived risk-standardized state mortality rates with medical record-derived estimates, the correlation coefficient was 0.86 (Standard Error = 0.032). Conclusions/Significance An administrative claims-based model for profiling hospitals for pneumonia mortality performs consistently over several years and produces hospital estimates close to those using a medical record model. PMID:21532758

  8. Optimizing Display, Analysis, Interpretation and Utility of Self-Monitoring of Blood Glucose (SMBG) Data for Management of Patients with Diabetes

    PubMed Central

    Rodbard, David

    2007-01-01

    Background Self-monitoring of blood glucose (SMBG) data have not been used to fullest advantage. Few physicians routinely download data from memory-equipped glucose meters and perform systematic analyses and interpretation of the data. There is need for improved methods for display and analysis of SMBG data, for a systematic approach for identification and prioritization of clinical problems revealed by SMBG, for characterization of blood glucose variability, and for clinical decision support. Methods We have developed a systematic approach to the analysis and interpretation of SMBG data to assist in the management of patients with diabetes. This approach utilizes the following criteria: 1) Overall quality of glycemic control; 2) Hypoglycemia (frequency, severity, timing); 3) Hyperglycemia; 4) Variability; 5) Pattern analysis; and 6) Adequacy of monitoring. The “Pattern analysis” includes assessment of: trends by date and by time of day; relationship of blood glucose to meals; post-prandial excursions; the effects of day of the week, and interactions between time of day and day of the week. Results The asymmetrical distribution of blood glucose values makes it difficult to interpret the mean and standard deviation. Use of the median (50th percentile) and Inter-Quartile Range (IQR) overcomes these difficulties: IQR is the difference between the 75th and 25th percentiles. SMBG data can be used to predict the A1c level and indices of the risks of hyperglycemia and hypoglycemia. Conclusion Given reliable measures of glucose variability, one can apply a strategy to progressively reduce glucose variability and then increase the intensity of therapy so as to reduce median blood glucose and hence A1c, while minimizing the risk of hypoglycemia. PMID:19888382

  9. The examination of relationship between socioeconomic factors and number of tuberculosis using quantile regression model for count data in Iran 2010-2011

    PubMed Central

    Sarvi, Fatemeh; Momenian, Somayeh; Khodadost, Mahmoud; Pahlavanzadeh, Bagher; Nasehi, Mahshid; Sekhavati, Eghbal

    2016-01-01

    Background: Poverty and low socioeconomic status are the most important reasons of increasing the global burden of tuberculosis, not only in developing countries but also in developed countries for particular groups. The purpose of this study was to assess the association between socioeconomic factors and the number of tuberculosis patients using quantile regression for count data. Methods: This cross-sectional study was conducted on 11,320 tuberculosis patients from March 2010 to March 201 in Iran. Data was gathered from the 345 sections of Iran by Ministry of Health and Medical Education and Statistical Center of Iran. The jittering method was applied for smoothing, and then, the quantile regression for count data was fitted. The AIC was used to compare the fitness of quantile regression for count data model and Poisson log-linear model. The R (3.0.1) software and Quantreg and AER packages were used for all analysis and modeling of the data. Results: The results of fitting the quantile regression for count data showed that in all percentiles, the more increase in immigration rate, illiteracy rate, unemployment and urbanization rates, the more tuberculosis morbidity rate was increased. The maximum increase of tuberculosis due to immigration rate, urbanization rate, unemployment rate, and illiteracy rate was in 95th percentile (β^=0.315), 85'Th percentile (β^=0.162), 75'Th percentile (β^=0.114 ), and 95'Th percentile (β^=0.304), respectively. For 50th percentiles and higher percentiles, with increasing the sum of physicians to the number of population, the tuberculosis morbidity rate was decreased, and the maximum decrease was in 95'Th percentile ( β^=-0.1). For all percentiles, the AIC showed that quantile regression for count data had been a better fit to data. Conclusion: With respect to the relationship between socioeconomic factors and TB rate, health care observers should pay close attention to improving these factors in Iran to reduce the TB mortality

  10. Reference Values for Body Composition and Anthropometric Measurements in Athletes

    PubMed Central

    Santos, Diana A.; Dawson, John A.; Matias, Catarina N.; Rocha, Paulo M.; Minderico, Cláudia S.; Allison, David B.; Sardinha, Luís B.; Silva, Analiza M.

    2014-01-01

    Background Despite the importance of body composition in athletes, reference sex- and sport-specific body composition data are lacking. We aim to develop reference values for body composition and anthropometric measurements in athletes. Methods Body weight and height were measured in 898 athletes (264 female, 634 male), anthropometric variables were assessed in 798 athletes (240 female and 558 male), and in 481 athletes (142 female and 339 male) with dual-energy X-ray absorptiometry (DXA). A total of 21 different sports were represented. Reference percentiles (5th, 25th, 50th, 75th, and 95th) were calculated for each measured value, stratified by sex and sport. Because sample sizes within a sport were often very low for some outcomes, the percentiles were estimated using a parametric, empirical Bayesian framework that allowed sharing information across sports. Results We derived sex- and sport-specific reference percentiles for the following DXA outcomes: total (whole body scan) and regional (subtotal, trunk, and appendicular) bone mineral content, bone mineral density, absolute and percentage fat mass, fat-free mass, and lean soft tissue. Additionally, we derived reference percentiles for height-normalized indexes by dividing fat mass, fat-free mass, and appendicular lean soft tissue by height squared. We also derived sex- and sport-specific reference percentiles for the following anthropometry outcomes: weight, height, body mass index, sum of skinfold thicknesses (7 skinfolds, appendicular skinfolds, trunk skinfolds, arm skinfolds, and leg skinfolds), circumferences (hip, arm, midthigh, calf, and abdominal circumferences), and muscle circumferences (arm, thigh, and calf muscle circumferences). Conclusions These reference percentiles will be a helpful tool for sports professionals, in both clinical and field settings, for body composition assessment in athletes. PMID:24830292

  11. A methodology to study multiple sclerosis (MS) based on distributions of standardized intensities in segmented tissue regions

    NASA Astrophysics Data System (ADS)

    Lei, T.; Udupa, J. K.; Odhner, D.; Mishra, S.; Wu, G.; Schwartz, E.; Ying, G.-S.; Iwanaga, T.; Desiderio, L.; Balcer, L.

    2006-03-01

    This paper presents (1) an improved hierarchical method for segmenting the component tissue regions in fast spin echo T2 and PD images of the brain of Multiple Sclerosis (MS) patients, and (2) a methodology to characterize the disease utilizing the distributions of standardized T2 and PD intensities in the segmented tissue regions. First, the background intensity inhomogeneities are corrected and the intensity scales are standardized for all acquired images. The segmentation method imposes a feedback-like procedure on our previously developed hierarchical brain tissue segmentation method. With gradually simplified patterns in images and stronger evidences, pathological objects are recognized and segmented in an interplay fashion. After the brain parenchymal (BP) mask is generated, an under-estimated gray matter mask (uGM) and an over-estimated white matter mask (oWM) are created. Pure WM (PWM) and lesion (LS) masks are extracted from the all-inclusive oWM mask. By feedback, accurate GM and WM masks are subsequently formed. Finally, partial volume regions of GM and WM as well as Dirty WM (DWM) masks are generated. Intensity histograms and their parameters (peak height, peak location, and 25th, 50th and 75th percentile values) are computed for both T2 and PD images within each tissue region. Tissue volumes are also estimated. Spearman correlation coefficient rank test is then utilized to assess if there exists a trend between clinical states and the image-based parameters. This image analysis method has been applied to a data set consisting of 60 patients with MS and 20 normal controls. LS related parameters and clinical Extended Disability Status Scale (EDSS) scores demonstrate modest correlations. Almost every intensity-based parameter shows statistical difference between normal control and patient groups with a level better than 5%. These results can be utilized to monitor disease progression in MS.

  12. A Streamflow Statistics (StreamStats) Web Application for Ohio

    USGS Publications Warehouse

    Koltun, G.F.; Kula, Stephanie P.; Puskas, Barry M.

    2006-01-01

    A StreamStats Web application was developed for Ohio that implements equations for estimating a variety of streamflow statistics including the 2-, 5-, 10-, 25-, 50-, 100-, and 500-year peak streamflows, mean annual streamflow, mean monthly streamflows, harmonic mean streamflow, and 25th-, 50th-, and 75th-percentile streamflows. StreamStats is a Web-based geographic information system application designed to facilitate the estimation of streamflow statistics at ungaged locations on streams. StreamStats can also serve precomputed streamflow statistics determined from streamflow-gaging station data. The basic structure, use, and limitations of StreamStats are described in this report. To facilitate the level of automation required for Ohio's StreamStats application, the technique used by Koltun (2003)1 for computing main-channel slope was replaced with a new computationally robust technique. The new channel-slope characteristic, referred to as SL10-85, differed from the National Hydrography Data based channel slope values (SL) reported by Koltun (2003)1 by an average of -28.3 percent, with the median change being -13.2 percent. In spite of the differences, the two slope measures are strongly correlated. The change in channel slope values resulting from the change in computational method necessitated revision of the full-model equations for flood-peak discharges originally presented by Koltun (2003)1. Average standard errors of prediction for the revised full-model equations presented in this report increased by a small amount over those reported by Koltun (2003)1, with increases ranging from 0.7 to 0.9 percent. Mean percentage changes in the revised regression and weighted flood-frequency estimates relative to regression and weighted estimates reported by Koltun (2003)1 were small, ranging from -0.72 to -0.25 percent and -0.22 to 0.07 percent, respectively.

  13. Technical note: Relationship between infrared thermography and heat production in young bulls.

    PubMed

    Gomes, R A; Busato, K C; Ladeira, M M; Johnson, K A; Galvão, M C; Rodrigues, A C; Lourençoni, D; Chizzotti, M L

    2016-03-01

    The traditional techniques to measure heat production (HP) are calorimetry (direct and indirect) and comparative slaughter. Both methods are expensive and require extensive amounts of time and infrastructure. Infrared thermography (IRT) could be a faster and less expensive alternative to estimate cattle HP. The objective of this project was to evaluate the use of the IRT technique as an indicator of HP in cattle. A total of 24 bulls (12 Nellore and 12 Black Angus) with initial BW of 380 ± 7 kg were used. Initially, 4 animals of each breed were harvested (baseline animals) and simple regressions were developed for each breed from these baseline animals to estimate the initial chemical composition of the remaining bulls. Eight animals of each breed were fed a silage/concentrate diet for ad libitum intake in individual stalls. On the 25th, 50th, and 75th experimental day, infrared thermal images (Fluke Ti 55ft; Fluke Corporation) were taken of each animal's face to access skin and ocular surface temperatures. A metabolism trial was conducted to estimate the ME intake (MEI). After 84 experimental days, the cattle were harvested and retained energy (RE) and HP were calculated. The data were analyzed using the MIXED and REG procedures of SAS adopting a significance level of 0.05. Angus cattle had a greater daily MEI, HP, and skin and eye temperatures than Nellore. We found significant correlations ( ≤ 0.005) between daily HP and maximum ( = 0.65) and average skin temperatures ( = 0.65) and maximum ( = 0.65) and average ocular surface ( = 0.69) temperatures recorded on d 50. Infrared thermography has potential to be used to evaluate HP in cattle. PMID:27065272

  14. Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations.

    PubMed

    Al-Subeihi, Ala A A; Alhusainy, Wasma; Kiwamoto, Reiko; Spenkelink, Bert; van Bladeren, Peter J; Rietjens, Ivonne M C M; Punt, Ans

    2015-03-01

    The present study aims at predicting the level of formation of the ultimate carcinogenic metabolite of methyleugenol, 1'-sulfooxymethyleugenol, in the human population by taking variability in key bioactivation and detoxification reactions into account using Monte Carlo simulations. Depending on the metabolic route, variation was simulated based on kinetic constants obtained from incubations with a range of individual human liver fractions or by combining kinetic constants obtained for specific isoenzymes with literature reported human variation in the activity of these enzymes. The results of the study indicate that formation of 1'-sulfooxymethyleugenol is predominantly affected by variation in i) P450 1A2-catalyzed bioactivation of methyleugenol to 1'-hydroxymethyleugenol, ii) P450 2B6-catalyzed epoxidation of methyleugenol, iii) the apparent kinetic constants for oxidation of 1'-hydroxymethyleugenol, and iv) the apparent kinetic constants for sulfation of 1'-hydroxymethyleugenol. Based on the Monte Carlo simulations a so-called chemical-specific adjustment factor (CSAF) for intraspecies variation could be derived by dividing different percentiles by the 50th percentile of the predicted population distribution for 1'-sulfooxymethyleugenol formation. The obtained CSAF value at the 90th percentile was 3.2, indicating that the default uncertainty factor of 3.16 for human variability in kinetics may adequately cover the variation within 90% of the population. Covering 99% of the population requires a larger uncertainty factor of 6.4. In conclusion, the results showed that adequate predictions on interindividual human variation can be made with Monte Carlo-based PBK modeling. For methyleugenol this variation was observed to be in line with the default variation generally assumed in risk assessment. PMID:25549870

  15. Stability of the Associations between Early Life Risk Indicators and Adolescent Overweight over the Evolving Obesity Epidemic

    PubMed Central

    Graversen, Lise; Sørensen, Thorkild I. A.; Petersen, Liselotte; Sovio, Ulla; Kaakinen, Marika; Sandbæk, Annelli; Laitinen, Jaana; Taanila, Anja; Pouta, Anneli

    2014-01-01

    Background Pre- and perinatal factors and preschool body size may help identify children developing overweight, but these factors might have changed during the development of the obesity epidemic. Objective We aimed to assess the associations between early life risk indicators and overweight at the age of 9 and 15 years at different stages of the obesity epidemic. Methods We used two population-based Northern Finland Birth Cohorts including 4111 children born in 1966 (NFBC1966) and 5414 children born in 1985–1986 (NFBC1986). In both cohorts, we used the same a priori defined prenatal factors, maternal body mass index (BMI), birth weight, infant weight (age 5 months and 1 year), and preschool BMI (age 2–5 years). We used internal references in early childhood to define percentiles of body size (<50, 50–75, 75–90 and >90) and generalized linear models to study the association with overweight, according to the International Obesity Taskforce (IOTF) definitions, at the ages of 9 and 15 years. Results The prevalence of overweight at the age of 15 was 9% for children born in 1966 and 16% for children born in 1986. However, medians of infant weight and preschool BMI changed little between the cohorts, and we found similar associations between maternal BMI, infant weight, preschool BMI, and later overweight in the two cohorts. At 5 years, children above the 90th percentile had approximately a 12 times higher risk of being overweight at the age of 15 years compared to children below the 50th percentile in both cohorts. Conclusions The associations between early body size and adolescent overweight showed remarkable stability, despite the increase in prevalence of overweight over the 20 years between the cohorts. Using consequently defined internal percentiles may be a valuable tool in clinical practice. PMID:24748033

  16. Assessment of human exposure to environmental sources of nickel in Europe: Inhalation exposure.

    PubMed

    Buekers, Jurgen; De Brouwere, Katleen; Lefebvre, Wouter; Willems, Hanny; Vandenbroele, Marleen; Van Sprang, Patrick; Eliat-Eliat, Maxime; Hicks, Keegan; Schlekat, Christian E; Oller, Adriana R

    2015-07-15

    The paper describes the inhalation nickel (Ni) exposure of humans via the environment for the regional scale in the EU, together with a tiered approach for assessing additional local exposure from industrial emissions. The approach was designed, in the context of REACH, for the purpose of assessing and controlling emissions and air quality in the neighbourhood of Ni producers and downstream users. Two Derived No Effect Level (DNEL) values for chronic inhalation exposure to total Ni in PM10 (20 and 60ngNi/m(3)) were considered. The value of 20ngNi/m(3) is the current EU air quality guidance value. The value of 60ngNi/m(3) is derived here based on recently published Ni data (Oller et al., 2014). Both values are protective for respiratory toxicity and carcinogenicity but differ in the application of toxicokinetic adjustments and cancer threshold considerations. Estimates of air Ni concentrations at the European regional scale were derived from the database of the European Environment Agency. The 50th and 90th percentile regional exposures were below both DNEL values. To assess REACH compliance at the local scale, measured ambient air data are preferred but are often unavailable. A tiered approach for the use of modelled ambient air concentrations was developed, starting with the application of the default EUSES model and progressing to more sophisticated models. As an example, the tiered approach was applied to 33 EU Ni sulphate producers' and downstream users' sites. Applying the EUSES model demonstrates compliance with a DNEL of 60ngNi/m(3) for the majority of sites, while the value of the refined modelling is demonstrated when a DNEL of 20ngNi/m(3) is considered. The proposed approach, applicable to metals in general, can be used in the context of REACH, for refining the risk characterisation and guiding the selection of risk management measures. PMID:25863314

  17. Fifteen-year trends in criteria air pollutants in oil sands communities of Alberta, Canada.

    PubMed

    Bari, Md; Kindzierski, Warren B

    2015-01-01

    An investigation of ambient air quality was undertaken at three communities within the Athabasca Oil Sands Region (AOSR) of Alberta, Canada (Fort McKay, Fort McMurray, and Fort Chipewyan). Daily and seasonal patterns and 15-year trends were investigated for several criteria air pollutants over the period of 1998 to 2012. A parametric trend detection method using percentiles from frequency distributions of 1h concentrations for a pollutant during each year was used. Variables representing 50th, 65th, 80th, 90th, 95th and 98th percentile concentrations each year were identified from frequency distributions and used for trend analysis. Small increasing concentration trends were observed for nitrogen dioxide (<1ppb/year) at Fort McKay and Fort McMurray over the period consistent with increasing emissions of oxides of nitrogen (ca. 1000tons/year) from industrial developments. Emissions from all oil sands facilities appear to be contributing to the trend at Fort McKay, whereas both emissions from within the community (vehicles and commercial) and oil sands facility emissions appear to be contributing to the trend at Fort McMurray. Sulfur dioxide (SO2) emissions from industrial developments in the AOSR were unchanged during the period (101,000±7000tons/year; mean±standard deviation) and no meaningful trends were judged to be occurring at all community stations. No meaningful trends occurred for ozone and fine particulate matter (PM2.5) at all community stations and carbon monoxide at one station in Fort McMurray. Air quality in Fort Chipewyan was much better and quite separate in terms of absence of factors influencing criteria air pollutant concentrations at the other community stations. PMID:25454237

  18. Data Base for a National Mineral-Resource Assessment of Undiscovered Deposits of Gold, Silver, Copper, Lead, and Zinc in the Conterminous United States

    USGS Publications Warehouse

    Ludington, S.D.; Cox, D.P.; McCammon, R.B.

    1996-01-01

    For this assessment, the conterminous United States was divided into 12 regions Adirondack Mountains, Central and Southern Rocky Mountains, Colorado Plateau, East Central, Great Basin, Great Plains, Lake Superior, Northern Appalachians, Northern Rocky Mountains, Pacific Coast, Southern Appalachians, and Southern Basin and Range. The assessment, which was conducted by regional assessment teams of scientists from the USGS, was based on the concepts of permissive tracts and deposit models. Permissive tracts are discrete areas of the United States for which estimates of numbers of undiscovered deposits of a particular deposit type were made. A permissive tract is defined by its geographic boundaries such that the probability of deposits of the type delineated occurring outside the boundary is neglible. Deposit models, which are based on a compilation of worldwide literature and on observation, are sets of data in a convenient form that describe a group of deposits which have similar characteristics and that contain information on the common geologic attributes of the deposits and the environments in which they are found. Within each region, the assessment teams delineated permissive tracts for those deposit models that were judged to be appropriate and, when the amount of information warranted, estimated the number of undiscovered deposits. A total of 46 deposit models were used to assess 236 separate permissive tracts. Estimates of undiscovered deposits were limited to a depth of 1 km beneath the surface of the Earth. The estimates of the number of undiscovered deposits of gold, silver, copper, lead, and zinc were expressed in the form of a probability distribution. Commonly, the number of undiscovered deposits was estimated at the 90th, 50th, and 10th percentiles. A Monte Carlo simulation computer program was used to combine the probability distribution of the number of undiscovered deposits with the grade and tonnage data sets associated with each deposit model to

  19. Effect of inhalation profile and throat geometry on predicted lung deposition of budesonide and formoterol (BF) in COPD: An in-vitro comparison of Spiromax with Turbuhaler.

    PubMed

    Chrystyn, Henry; Safioti, Guilherme; Keegstra, Johan René; Gopalan, Gokul

    2015-08-01

    Successful delivery of inhalation medication to the lungs can be affected by the inhalation manoeuvre used. Conventional in-vitro testing of the emitted dose from a dry powder inhaler (DPI) uses a vacuum pump to simulate an inhalation. We have adapted this method by replacing the pump with patient inhalation profiles and an anatomical throat. Three anatomical throat sizes and three inhalation profiles were used. The profiles represented the 10th, 50th and 90th percentiles of peak inhalation flow and acceleration of flow from a population of 50 COPD patients inhaling through empty Spiromax and Turbuhaler devices. Combining the dose emission results for the three throat sizes, the mean (SD) budesonide fine-particle dose (FPD) from budesonide-formoterol Spiromax 320/9 μg was 78.91 (20.18), 79.91 (15.36) and 75.10 (19.91)μg and the total emitted dose (TED) of budesonide was 263.69 (40.74), 261.20 (21.65) and 261.61 (45.65)μg. Similarly, the FPD from 320/9 μg Turbuhaler was 22.45 (3.24), 52.20 (12.57) and 69.11 (75.10)μg with a TED of 143.80 (14.90), 149.50 (26.61) and 158.61 (43.04)μg. Spiromax showed greater consistency than Turbuhaler over a range of inspiratory flow profiles. The results demonstrate the value of this new method to assess the doses that patients receive during real-life use of their DPI. PMID:26043823

  20. The Impact of Heat Islands on Mortality in Paris during the August 2003 Heat Wave

    PubMed Central

    Zeghnoun, Abdelkrim; Dousset, Bénédicte; Bretin, Philippe; Vandentorren, Stéphanie; Giraudet, Emmanuel; Beaudeau, Pascal

    2011-01-01

    Background: Heat waves have a drastic impact on urban populations, which could increase with climate change. Objectives: We evaluated new indicators of elderly people’s exposure to heat in Paris, from a public health prevention perspective, using satellite thermal images. Methods: We used a time series of 61 images from the satellites of the National Oceanic and Atmospheric Administration’s (NOAA) Advanced Very High Resolution Radiometer (AVHRR) taken from 1 to 13 August 2003 to produce thermal indicators of minimum, maximum, and mean surface temperatures and diurnal temperature amplitude, with different lags between the meteorological data and the health impact. Health data came from a case–control study involving 241 people ≥ 65 years of age who died in the city of Paris or the nearby suburban area of Val-de-Marne during the August 2003 heat wave, and 241 controls who were matched to cases on age, sex, and residential zone. For each person, we integrated the thermal indicators in a conditional logistic regression model, adjusted for age and other potential confounders. We computed odds ratios (ORs) comparing the 90th and 50th percentiles of the temperature differences between cases and controls for various indicators. Results: Mortality risk was significantly associated with exposure for two indicators: minimum temperatures averaged for 1–13 August [for a 0.41°C increase, OR = 2.17; 95% confidence interval (CI): 1.14, 4.16] and minimum temperature averaged on the day of death and the 6 preceding days (for a 0.51°C increase: OR = 2.24; 95% CI: 1.03, 4.87). Conclusions: Our results support the influence of night temperatures on the health impact of heat waves in urban areas. Urban heat exposure indicators based on satellite imagery have the potential to identify areas with higher risk of death, which could inform intervention decisions by key stakeholders. PMID:21885383

  1. High-fructose corn syrup and sucrose have equivalent effects on energy-regulating hormones at normal human consumption levels.

    PubMed

    Yu, Zhiping; Lowndes, Joshua; Rippe, James

    2013-12-01

    Intake of high-fructose corn syrup (HFCS) has been suggested to contribute to the increased prevalence of obesity, whereas a number of studies and organizations have reported metabolic equivalence between HFCS and sucrose. We hypothesized that HFCS and sucrose would have similar effects on energy-regulating hormones and metabolic substrates at normal levels of human consumption and that these values would not change over a 10-week, free-living period at these consumption levels. This was a randomized, prospective, double-blind, parallel group study in which 138 adult men and women consumed 10 weeks of low-fat milk sweetened with either HFCS or sucrose at levels of the 25th, 50th, and 90th percentile population consumption of fructose (the equivalent of 40, 90, or 150 g of sugar per day in a 2000-kcal diet). Before and after the 10-week intervention, 24-hour blood samples were collected. The area under the curve (AUC) for glucose, insulin, leptin, active ghrelin, triglyceride, and uric acid was measured. There were no group differences at baseline or posttesting for all outcomes (interaction, P > .05). The AUC response of glucose, active ghrelin, and uric acid did not change between baseline and posttesting (P > .05), whereas the AUC response of insulin (P < .05), leptin (P < .001), and triglyceride (P < .01) increased over the course of the intervention when the 6 groups were averaged. We conclude that there are no differences in the metabolic effects of HFCS and sucrose when compared at low, medium, and high levels of consumption. PMID:24267044

  2. Consumption of sucrose and high-fructose corn syrup does not increase liver fat or ectopic fat deposition in muscles.

    PubMed

    Bravo, Stephen; Lowndes, Joshua; Sinnett, Stephanie; Yu, Zhiping; Rippe, James

    2013-06-01

    It has been postulated that fructose-induced triglyceride synthesis is augmented when accompanied by glucose. Chronic elevations could lead to excess fat accumulation in the liver and ectopic fat deposition in muscles, which in turn could contribute to the induction of abnormalities in glucose homeostasis, insulin resistance, and the subsequent development of type 2 diabetes. Our objective was to evaluate the effect of the addition of commonly consumed fructose- and (or) glucose-containing sugars in the usual diet on liver fat content and intramuscular adipose tissue. For 10 weeks, 64 individuals (mean age, 42.16 ± 11.66 years) consumed low-fat milk sweetened with either high-fructose corn syrup (HFCS) or sucrose; the added sugar matched consumption levels of fructose in the 25th, 50th, and 90th percentiles of the population. The fat content of the liver was measured with unenhanced computed tomography imaging, and the fat content of muscle was assessed with magnetic resonance imaging. When the 6 HFCS and sucrose groups were averaged, there was no change over the course of 10 weeks in the fat content of the liver (13.32% ± 10.49% vs. 13.21% ± 10.75%; p > 0.05), vastus lateralis muscle (3.07 ± 0.74 g per 100 mL vs. 3.15 ± 0.84 g per 100 mL; p > 0.05), or gluteus maximus muscle (4.08 ± 1.50 g per 100 mL vs. 4.24 ± 1.42 g per 100 mL; p > 0.05). Group assignment did not affect the result (interaction > 0.05). These data suggest that when fructose is consumed as part of a typical diet in normally consumed sweeteners, such as sucrose or HFCS, ectopic fat storage in the liver or muscles is not promoted. PMID:23724887

  3. A case-control study to examine the association between breastfeeding during late pregnancy and risk of a small-for-gestational-age birth in Lima, Peru.

    PubMed

    Pareja, Rossina G; Marquis, Grace S; Penny, Mary E; Dixon, Philip M

    2015-04-01

    Excessive demands on maternal nutritional status may be a risk factor for poor birth outcomes. This study examined the association between breastfeeding during late pregnancy (≥ 28 weeks) and the risk of having a small-for-gestational-age (SGA) newborn, using a matched case-control design (78 SGA cases: birthweight <10th percentile for gestational age; 150 non-SGA controls: 50th percentile 90th percentile for gestational age). Between March 2006 and April 2007, project midwives visited daily three government hospitals in Lima, Peru and identified cases and matched controls based on hospital, gestational age, and inter-gestational period. Mothers were interviewed and clinical chart extractions were completed. Factors associated with risk of SGA were assessed by their adjusted odds ratios (aOR) from conditional logistic regression. Exposure to an overlap of breastfeeding during late pregnancy was not associated with an increased risk of having a SGA newborn [aOR=0.58, 95% confidence interval (CI): 0.10-3.30]. However, increased risk was associated with having a previous low-birthweight birth (aOR=6.53; 95% CI: 1.43-29.70) and a low intake of animal source foods (<25th percentile; aOR=2.26; 95% CI: 1.01-5.04), and tended to be associated with being short (<150 cm; aOR=2.05; 95% CI: 0.92-4.54). This study found no evidence to support the hypothesis that breastfeeding during late pregnancy increases the risk for SGA; however, studies with greater statistical power are needed to definitively examine this possible association and clarify whether there are other risks to the new baby, the toddler and the pregnant woman. PMID:23020780

  4. Climatology of Extreme Winds in the Chukchi/Beaufort Seas/Alaska Region Using the North American Regional Reanalysis

    NASA Astrophysics Data System (ADS)

    Stegall, S. T.; Zhang, J.

    2009-12-01

    The high-resolution (32km, 3-hourly) North American Regional Reanalysis (NARR) surface winds were used to examine the detailed structures of the distribution and evolution of the surface wind across the Chukchi/Beaufort Seas/Alaska region. First the NARR surface winds were verified against the station observations over the study area and the comparisons indicate that NARR essentially captures the distribution of the observed winds in summer. However, an obvious bias exists in winter, when the easterly component of the bimodal pattern is overestimated, while the westerly component is underestimated, particularly in January. Then we used the NARR surface wind data to examine the wind field climatological features, interannual variability and long-term change over the study area by analyzing the monthly maximums, 99th, 95th, 90th, and 50th percentile wind speeds (m/s) for each month of the year from 1979-2006. Decadal differences (i.e. the difference from 2000-2006 and 1990-1999 and 1990-1999 and 1980-1989) were also investigated to understand the long-term change in the area's surface winds. The results indicated that the maximum wind speeds in the Chukchi/Beaufort Seas have lower values from January through May. Then there is a progression northward of the higher wind speeds beginning in the Bering Strait in June and continuing into the Chukchi/Beaufort Seas during July-October; in November and December the maximum winds in the area start to decrease with a southward migration into the Chukchi Sea and eventually back through the Bering Strait into the Bering Sea, which is coincident with the sea ice retreat and advance in the area. The yearly variance of the wind speeds follow a similar northward and southward migration while the highest variance happened in October. The decadal differences mainly show a large increase in the maximum winds speeds in September and October in the Chukchi Sea.

  5. Using multi-frequency radar and discrete-return LiDAR measurements to estimate above-ground biomass and biomass components in a coastal temperate forest

    NASA Astrophysics Data System (ADS)

    Tsui, Olivier W.; Coops, Nicholas C.; Wulder, Michael A.; Marshall, Peter L.; McCardle, Adrian

    2012-04-01

    Height measurements from small-footprint discrete-return LiDAR and backscatter coefficients from C- and L-band radar were used independently and in combination to estimate above-ground component and total biomass for a coniferous temperate forest, located on Vancouver Island, British Columbia, Canada. Reference biomass data were obtained from plot-level data and used for comparison against the LiDAR and radar-based biomass models. For the LiDAR-only model, height metrics such as mean first return height and percentiles (e.g., 10th and 90th) of first returns correlated best to total above-ground and stem biomass. While percent of first returns above 2 m and percentiles (75th and 90th) of first returns height metrics correlated best to crown biomass. A comparison between above-ground components and total biomass indicate that stem biomass displayed the highest relationship with the LiDAR measurements while crown biomass showed the lowest relationship with relative root mean squared error ranging from 16% to 22%, respectively. Alternatively, the radar-only models indicated that for C-band radar, a combination of HH and VV backscatter demonstrated the most significant correlation with forest biomass compared to coherence based models with a relative root mean squared error of 53%. For L-band radar, a combination of HH and HV backscatter showed the most significant correlation compared to coherence based models with a relative root mean squared error of 44%. Exploring a mixture of C- and L-band backscatter and coherence based models revealed that a combination of C-HV and L-HV coherence magnitudes provided the best radar relationship with forest biomass with a relative root mean squared error of 35%. Also for all radar-based models, L- and C-band backscatter and coherence magnitudes were poorly correlated with individual biomass components when compared to total above-ground biomass. The addition of C- and L-band backscatter and coherence variables to the Li

  6. Calibration and evaluation of the Canadian Forest Fire Weather Index (FWI) System for improved wildland fire danger rating in the United Kingdom

    NASA Astrophysics Data System (ADS)

    de Jong, Mark C.; Wooster, Martin J.; Kitchen, Karl; Manley, Cathy; Gazzard, Rob; McCall, Frank F.

    2016-05-01

    generally have the greatest predictive skill for landscape fire activity across Great Britain, with performance varying seasonally and by land cover type. At the height of the most recent severe wildfire period in the UK (2 May 2011), 50 % of all wildfires occurred in areas where the FWI component exceeded the 99th percentile. When all wildfire events during the 2010-2012 period are considered, the 75th, 90th and 99th percentiles of at least one FWI component were exceeded during 85, 61 and 18 % of all wildfires respectively. Overall, we demonstrate the significant advantages of using a percentile-based calibration approach for classifying UK fire danger, and believe that our findings provide useful insights for future development of the current operational MOFSI UK FDRS.

  7. T1-Weighted Dynamic Contrast-Enhanced MRI as a Noninvasive Biomarker of Epidermal Growth Factor Receptor vIII Status

    PubMed Central

    Arevalo-Perez, J.; Thomas, A.A.; Kaley, T.; Lyo, J.; Peck, K.K.; Holodny, A.I.; Mellinghoff, I.K.; Shi, W.; Zhang, Z.; Young, R.J.

    2016-01-01

    BACKGROUND AND PURPOSE Epidermal growth factor receptor variant III is a common mutation in glioblastoma, found in approximately 25% of tumors. Epidermal growth factor receptor variant III may accelerate angiogenesis in malignant gliomas. We correlated T1-weighted dynamic contrast-enhanced MR imaging perfusion parameters with epidermal growth factor receptor variant III status. MATERIALS AND METHODS Eighty-two consecutive patients with glioblastoma and known epidermal growth factor receptor variant III status who had dynamic contrast-enhanced MR imaging before surgery were evaluated. Volumes of interest were drawn around the entire enhancing tumor on contrast T1-weighted images and then were transferred onto coregistered dynamic contrast-enhanced MR imaging perfusion maps. Histogram analysis with normalization was performed to determine the relative mean, 75th percentile, and 90th percentile values for plasma volume and contrast transfer coefficient. A Wilcoxon rank sum test was applied to assess the relationship between baseline perfusion parameters and positive epidermal growth factor receptor variant III status. The receiver operating characteristic method was used to select the cutoffs of the dynamic contrast-enhanced MR imaging perfusion parameters. RESULTS Increased relative plasma volume and increased relative contrast transfer coefficient parameters were both significantly associated with positive epidermal growth factor receptor variant III status. For epidermal growth factor receptor variant III–positive tumors, relative plasma volume mean was 9.3 and relative contrast transfer coefficient mean was 6.5; for epidermal growth factor receptor variant III–negative tumors, relative plasma volume mean was 3.6 and relative contrast transfer coefficient mean was 3.7 (relative plasma volume mean, P < .001, and relative contrast transfer coefficient mean, P = .008). The predictive powers of relative plasma volume histogram metrics outperformed those of the

  8. Association of Apparent Diffusion Coefficient with Disease Recurrence in Patients with Locally Advanced Cervical Cancer Treated with Radical Chemotherapy and Radiation Therapy.

    PubMed

    Gladwish, Adam; Milosevic, Michael; Fyles, Anthony; Xie, Jason; Halankar, Jaydeep; Metser, Ur; Jiang, Haiyan; Becker, Nathan; Levin, Wilfred; Manchul, Lee; Foltz, Warren; Han, Kathy

    2016-04-01

    Purpose To investigate whether volumetrically derived apparent diffusion coefficient (ADC) from pretreatment diffusion-weighted (DW) magnetic resonance (MR) imaging is associated with disease recurrence in women with locally advanced cervical cancer treated with chemotherapy and radiation therapy. Materials and Methods An ethics board-approved, retrospective study was conducted in 85 women with stage IB-IVA cervical cancer treated with chemo- and radiation therapy in 2009-2013. All patients underwent MR imaging for staging, including T2-weighted and DW MR imaging series, by using a 1.5- or 3.0-T imager. The mean, median, 75th, 90th, and 95th percentile ADCs (ADCmean, ADC50, ADC75, ADC90, and ADC95, respectively) of all voxels that comprised each tumor were extracted and normalized to the mean urine ADC (nADCmean, nADC50, nADC75, nADC90, and nADC95, respectively) to reduce variability. The primary outcome was disease-free survival (DFS). Uni- and multivariable Cox regression analyses were used to evaluate the association of ADC parameters and relevant clinical variables with DFS. Results Of the 85 women included, 62 were free of disease at last follow-up. Median follow-up was 37 months (range, 5-68 months). Significant variables at univariable analysis included T2-weighted derived tumor diameter, para-aortic nodal involvement, advanced stage, ADC90 and ADC95, nADC75, nADC90, and nADC95. Normalized parameters were more highly associated (hazard ratio per 0.01 increase in normalized ADC, 0.91-0.94; P < .04). Because nADC75, nADC90, and nADC95 were highly correlated, only nADC95 (which had the lowest P value) was included in multivariable analysis. At multivariable analysis, absolute and normalized ADC95 remained associated with DFS (hazard ratio, 0.90-0.98; P < .05). Conclusion The volumetric ADC95 may be a useful imaging metric to predict treatment failure in patients with locally advanced cervical cancer treated with chemo- and radiation therapy. (©) RSNA, 2015

  9. Relationship between extreme Precipitation and Temperature over Japan: An analysis from Multi-GCMs and Multi-RCMs products

    NASA Astrophysics Data System (ADS)

    Nayak, S.; Dairaku, K.; Takayabu, I.

    2014-12-01

    According to the IPCC reports, the concentration of CO­2 has been increasing and projected to be increased significantly in future (IPCC, 2012). This can have significant impacts on climate. For instance, Dairaku and Emori (2006) examined over south Asia by doubling CO2 and documented an increase in precipitation intensities during Indian summer monsoon. This would increase natural disasters such as floods, landslide, coastal disaster, erosion etc. Recent studies investigated whether the rate of increase of extreme precipitation is related with the rate expected by Clausius-Clapeyron (CC) relationship (approximately 7% per degree temperature rise). In our study, we examine whether this rate can increase or decrease in the future regional climate scenarios over Japan. We have analysed the ensemble experiments by three RCMs(NHRCM, NRAMS, WRF) forced by JRA25 as well as three GCMs (CCSM4, MIROC5, MRI-GCM3) for the current climate (1981-2000) and future scenario (2081-2100, RCP4.5) over Japan. We have stratified the extreme (99th, 95th, 90th, 75th percentile) precipitation of daily sum and daily maximum of hourly precipitation intensities of wet events based on daily mean temperature in bins of 1°C width for annual as well as for each season (DJF, MAM, JJA, SON). The results indicate that precipitation intensity increases when temperature increases roughly up to 22 °C and further increase of temperature decreases the precipitation intensities. The obtained results are consistent and match with the observation (APHRODITE dataset) over Japan. The decrease of precipitation at higher temperature mainly can be found in JJA. It is also noticed that the rate of specific humidity is estimated higher during JJA than other seasons. The rate of increase of extreme precipitation is similar to the rate expected by CC relation except DJF (nearly twice of CC relation) in current climate. This rate becomes to be significantly larger in future scenario for higher temperatures than

  10. A post-remediation assessment in Jersey City of the association of hexavalent chromium in house dust and urinary chromium in children.

    PubMed

    Black, Kathleen; Gochfeld, Michael; Lioy, Paul J; Fan, Zhi-Hua Tina; Yu, Chang Ho; Jeitner, Chris; Hernandez, Marta; Einstein, Stephanie A; Stern, Alan H

    2015-01-01

    Although all chromite ore processing residue (COPR) sites near residential neighborhoods in Jersey City, New Jersey have undergone remediation, recent studies found widespread, but low levels of hexavalent chromium (Cr(+6)) in house dust both in Jersey City and in communities with no known sources of Cr(+6). This study was designed as a follow-up to determine whether there is an association between current Cr(+6) levels in house dust and urinary chromium concentrations in young children. Dust samples (N=369) were collected from 123 homes. The median Cr(+6) concentration was 3.3 μg/g (mean±SD 5.2±7.5) and the median Cr(+6) loading was 1.1 μg/m(2) (1.9±3.1). These levels were not elevated compared with previously reported levels in background communities (median concentration=3.5 μg/g; median loading=2.8 μg/m(2)). Urinary chromium concentrations were measured in spot urine samples collected from 150 children, ages 3 months to 6 years. The median uncorrected urinary chromium concentration was 0.19 μg/l (0.22±0.16). Current urinary chromium concentrations were significantly lower than those previously reported before and during remediation (t-test; P<0.001). Urinary chromium concentrations were not significantly higher in homes with high (75th or 90th percentile) Cr(+6) dust levels (concentration or loading) compared with other homes. Multiple linear regression was used to examine the relationship between Cr(+6) levels (concentration and loading) in house dust and urinary chromium concentrations (uncorrected and specific gravity corrected). Contrary to pre-remediation studies, we did not find a positive association between Cr(+6) levels in house dust and urinary chromium concentrations. The findings indicate that current Cr(+6) levels in house dust are not positively associated with children's chromium exposure as measured by urinary chromium, and the children's exposure to Cr(+6) in house dust is below the level that could be identified by urine

  11. Macrosomia Predictors in Infants Born to Cuban Mothers with Gestational Diabetes.

    PubMed

    Cruz, Jeddú; Grandía, Raiden; Padilla, Liset; Rodríguez, Suilbert; Hernández García, Pilar; Lang Prieto, Jacinto; Márquez-Guillén, Antonio

    2015-07-01

    INTRODUCTION Fetal macrosomia is the most important complication in infants of women with diabetes, whether preconceptional or gestational. Its occurrence is related to certain maternal and fetal conditions and negatively affects maternal and perinatal outcomes. The definitive diagnosis is made at birth if a newborn weighs >4000 g. OBJECTIVE Identify which maternal and fetal conditions could be macrosomia predictors in infants born to Cuban mothers with gestational diabetes. METHODS A case-control study comprising 236 women with gestational diabetes who bore live infants (118 with macrosomia and 118 without) was conducted in the América Arias University Maternity Hospital, Havana, Cuba, during 2002-2012. The dependent variable was macrosomia (birth weight >4000 g). Independent maternal variables included body mass index at pregnancy onset, overweight or obesity at pregnancy onset, gestational age at diabetes diagnosis, pregnancy weight gain, glycemic control, triglycerides and cholesterol. Fetal variables examined included third-semester fetal abdominal circumference, estimated fetal weight at ≥28 weeks (absolute and percentilized by Campbell and Wilkin, and Usher and McLean curves). Chi square was used to compare continuous variables (proportions) and the student t test (X ± SD) for categorical variables, with significance threshold set at p <0.05. ORs and their 95% CIs were calculated. RESULTS Significant differences between cases and controls were found in most variables studied, with the exception of late gestational diabetes diagnosis, total fasting cholesterol and hypercholesterolemia. The highest OR for macrosomia were for maternal hypertriglyceridemia (OR 4.80, CI 2.34-9.84), third-trimester fetal abdominal circumference >75th percentile (OR 7.54, CI 4.04-14.06), and estimated fetal weight >90th percentile by Campbell and Wilkin curves (OR 4.75, CI 1.42-15.84) and by Usher and McLean curves (OR 8.81, CI 4.25-18.26). CONCLUSIONS Most variables assessed

  12. The Effects of Oxygen Concentration on Benthic Foraminiferal Growth and Size

    NASA Astrophysics Data System (ADS)

    Ng, B.; Keating-Bitonti, C.; Payne, J.

    2015-12-01

    Many organisms use oxygen through cellular respiration in order to gain energy. For this reason, oxygen has a significant influence on organism size and growth. The amount of oxygen an organism needs depends on its metabolic demand, which is partially a function organism size (i.e., mass). The Santa Monica Basin (SMB) is an oxygen minimum zone located off the southern coast of California that maintains a steep oxygen gradient and is thus an ideal location for conducting research on how oxygen influences organism size. Here we use benthic foraminifera, widespread single-celled protists that produce shells (tests), to study the controls of oxygen on organism size. Because cell mass and cell volume are correlated, we study trends in the log test volume of four abundant species from SMB: Uvigerina peregrina, Bolivina spissa, B. argentea, Loxostomum pseudobeyrichi. These foraminifera make multi-chambered tests, thus we also count the number of chambers per specimen in order to further assess their growth under varying oxygen concentrations. We analyzed the data using quantile regressions to determine trends in not only median values of the log test volume and number of chambers as a function of oxygen concentrations, but also in the 10th, 25th, 75th, and 90th percentiles because oxygen availability often constrains the maximum and minimum size of organisms. Our results show a positive correlation between oxygen concentration and the maximum log test volumes of L. pseudobeyrichi and B. argentea, supporting our hypothesis. However, we observed a negative correlation between oxygen concentration and the maximum percentiles of log test volume in U. peregrina. Nevertheless, U. peregrina still displays a positive correlation between chamber number and oxygen concentrations in line with our hypothesis. The preponderance of trends supporting a direct correlation between log test volume or chamber number and oxygen concentration suggest that oxygen limits the maximum obtainable

  13. Exposure to ambient air pollution in Canada and the risk of adult leukemia.

    PubMed

    Winters, Nicholas; Goldberg, Mark S; Hystad, Perry; Villeneuve, Paul J; Johnson, Kenneth C

    2015-09-01

    There is a paucity of studies investigating adult leukemia and air pollution. To address this gap, we analyzed data from a Canadian population-based case-control study conducted in 1994-1997. Cases were 1064 adults with incident leukemia and controls were 5039 healthy adults. We used data from satellites and fixed-site monitoring stations to estimate residential concentrations of NO2 and fine particulate matter (PM2.5) for the period prior to diagnosis, starting in 1975 and ending in 1994. We modeled the average annual exposure of each subject. Odds ratios (OR) and their 95% confidence intervals (CI) were estimated using logistic regression, adjusted for age, gender, province, smoking, education, body mass index, income, and self-reported exposures to ionizing radiation and benzene. We found an 'n-shaped' response function between exposure to NO2 and all forms of leukemia: from the tenth percentile to the median (4.51 to 14.66 ppb), the OR was 1.20; 95% CI: 0.97-1.48 and from the 75th percentile to the 90th (22.75 to 29.7 ppb), the OR was 0.79; 95% CI 0.68-0.93. For PM2.5 we found a response function consistent with a linear model, with an OR per 10 μg/m(3) of 0.97 (95% CI 0.75-1.26). For chronic lymphocytic leukemia we found response functions that were consistent with a simple linear model, with an OR per 5 ppb of NO2 of 0.93 (95% CI 0.86-1.00) and an OR per 10 μg/m(3) of PM2.5 of 0.62 (95% CI 0.42-0.93). In summary, for chronic lymphocytic leukemia we found no evidence of an association with air pollution and with all forms of leukemia we found weak evidence of an association only at low concentrations of NO2. It is possible that these inconsistent results may have arisen because of unaccounted urban/rural differences or possibly from a selection effect, especially among controls. PMID:25955692

  14. Tea consumption and risk of cancer of the colon and rectum.

    PubMed

    Cerhan, J R; Putnam, S D; Bianchi, G D; Parker, A S; Lynch, C F; Cantor, K P

    2001-01-01

    The association between tea consumption and risk of colon and rectal cancers was investigated in a population-based case-control study conducted in Iowa (United States). Colon (n = 685) and rectal (n = 655) cancer cases age 40-85 yr were identified through the Iowa Surveillance, Epidemiology, and End Results (SEER) Cancer Registry (86% response rate); controls (n = 2,434) were frequency matched by sex and 5-yr age group (80% response rate). The usual adult consumption of tea (hot and iced), along with other information including dietary data, was self-reported using a mailed questionnaire. Total tea consumption (cups/day) was categorized as none (reference category), low (< 3.1), medium (3.1-5.0), and high (> 5.0), with cut points for tea consumers based on the 75th and 90th percentiles of use among controls. Unconditional logistic regression was used to estimate the odds ratios (ORs) and 95% confidence intervals. There was no association between total tea consumption and colon cancer (ORs = 1.0, 1.1, 1.3, and 0.7) or rectal cancer (ORs = 1.0, 0.9, 1.4, and 1.0) after adjustment for age, sex, education, physical activity, smoking history, and intake of coffee, fiber, and fruits and vegetables. Results were similar when hot tea and iced tea were evaluated individually. Further adjustment for other colorectal cancer risk factors did not alter these results. There was no association with proximal or distal colon cancer. There was also no interaction between tea consumption and any of the dietary variables or total fluid on risk of colon or rectal cancer, with the exception of a suggestive positive association between an increasing frequency of tea consumption and colon cancer risk among current smokers (multivariate ORs = 1.0, 1.4, 2.0, and 1.8; P for trend = 0.1), but not among never smokers (multivariate ORs = 1.0, 1.0, 1.1, and 0.4; P for trend = 0.3). These data do not support an overall association, either positive or negative, between tea consumption and risk of

  15. Women in Action: Rebels and Reformers 1920-1980.

    ERIC Educational Resources Information Center

    Perry, Elisabeth Israels

    This book, celebrating the 75th anniversary of the 19th Amendment as well as the 75th anniversary of the League of Women Voters, argues that U.S. women always have been political, even when they were excluded from party membership, voting and running for office. Political expression could be found in early temperance societies, antislavery…

  16. Hepcidin and Risk for Anemia in CKD: A Cross-sectional and Longitudinal Analysis in the CKiD Cohort

    PubMed Central

    Atkinson, Meredith A.; Kim, Ji Young; Roy, Cindy N.; Warady, Bradley A.; White, Colin T.; Furth, Susan L.

    2014-01-01

    Background Hepcidin, a key iron regulatory protein, is elevated in patients with chronic kidney disease (CKD). Its role in the development and progression of the anemia of CKD in children remains poorly defined. Methods Cross-sectional and longitudinal study in children aged 1–16 years with stage 2–4 CKD in the Chronic Kidney Disease in Children (CKiD) cohort (n=133) with hepcidin measured at baseline and hemoglobin (HGB) measured annually in follow-up. Anemia was defined as HGB < 5th percentile for age/sex OR treatment with an erythropoiesis stimulating agent (ESA). Results Hepcidin levels correlated negatively with glomerular filtration rate (GFR) (r=−0.22, p=0.01) and positively with ferritin (r=0.67, p<0.001). At the lower end of the GFR spectrum at baseline (10th percentile, 27.5 ml/min/1.73m2), higher hepcidin was associated with a 0.87 g/dL decrease in HGB during follow-up (95% CI −1.69, −0.05 g/dL, p=0.038). At higher GFR percentiles there was no significant association between baseline hepcidin and HGB during follow-up. Among 90 non-anemic subjects at baseline, 23.3% developed incident anemia. In subjects with GFR ≤ the median, a higher hepcidin level was associated with an increased risk for incident anemia (at 10th %ile GFR, HR 3.471, 95% CI 1.228, 9.810, p=0.019; at 25th %ile GFR HR 2.641, 95% CI 1.213, 5.750, p=0.014; at 50th %ile GFR, HR 1.953, 95% CI 1.011, 3.772, p=0.046). Among subjects with GFR in the 75th percentile or above, incrementally higher baseline hepcidin was not associated with increased anemia risk. Conclusions Higher hepcidin levels are associated with a decreased HGB and an increased risk for incident anemia, and this association is most significant among subjects with lower GFR. PMID:25380788

  17. Computed tomography-defined abdominal adiposity is associated with acute kidney injury in critically ill trauma patients

    PubMed Central

    Shashaty, Michael G. S.; Kalkan, Esra; Bellamy, Scarlett L.; Reilly, John P.; Holena, Daniel N.; Cummins, Kathleen; Lanken, Paul N.; Feldman, Harold I.; Reilly, Muredach P.; Udupa, Jayaram K.; Christie, Jason D.

    2014-01-01

    Objective Higher body mass index (BMI) is associated with increased risk of acute kidney injury (AKI) after major trauma. Since BMI is non-specific, reflecting lean, fluid, and adipose mass, we evaluated the use of computed tomography (CT) to determine if abdominal adiposity underlies the BMI-AKI association. Design Prospective cohort study. Setting Level I Trauma Center of a university hospital. Patients Patients older than 13 years with an Injury Severity Score ≥16 admitted to the trauma intensive care unit were followed for development of AKI over five days. Those with isolated severe head injury or on chronic dialysis were excluded. Interventions None Measurements and Main Results Clinical, anthropometric, and demographic variables were collected prospectively. CT images at the level of the L4-5 intervertebral disc space were extracted from the medical record and used by two operators to quantitate visceral and subcutaneous adipose tissue (VAT and SAT, respectively) areas. AKI was defined by Acute Kidney Injury Network (AKIN) creatinine and dialysis criteria. Of 400 subjects, 327 (81.8%) had CT scans suitable for analysis: 264/285 (92.6%) blunt trauma subjects, 63/115 (54.8%) penetrating trauma subjects. VAT and SAT areas were highly correlated between operators (ICC>0.999, p<0.001 for each) and within operator (ICC>0.999, p<0.001 for each). In multivariable analysis, the standardized risk of AKI was 15.1% (95% CI 10.6%,19.6%), 18.1% (14%,22.2%), and 23.1% (18.3%,27.9%) at the 25th, 50th, and 75th percentiles of VAT area, respectively (p=0.001), with similar findings when using SAT area as the adiposity measure. Conclusions Quantitation of abdominal adiposity using CT scans obtained for clinical reasons is feasible and highly reliable in critically ill trauma patients. Abdominal adiposity is independently associated with AKI in this population, confirming that excess adipose tissue contributes to the BMI-AKI association. Further studies of the potential

  18. Ecosystem Mapping Approaches Based on Vegetation Structure Using NEON Prototype Airborne LiDAR and Field Data

    NASA Astrophysics Data System (ADS)

    Krause, K.; Emery, W. J.; Barnett, D.; Petroy, S. B.; Meier, C. L.; Wessman, C. A.

    2014-12-01

    Remote sensing is a powerful tool for measuring the current state of vegetation and monitoring changes over time with repeated data collections. Airborne Light Detection and Ranging (LiDAR) data is especially well suited for mapping 3D vegetation structure. In 2010, the National Ecological Observatory Network (NEON) contracted LiDAR and hyperspectral airborne data collections over the Ordway-Swisher Biological Station (OSBS). Ground truth campaigns were also conducted in 2010, 2011, and 2014 including structural measurements and generation of species lists for a set of ground validation plots. The vegetation communities at OSBS can be characterized by the Florida Natural Areas Inventory (FNAI) classification system, with a large area of the property belonging to the Sandhill community. For this study, classification algorithm training locations are hand selected for each FNAI community type using photo-interpretation. A series of LiDAR metrics are calculated on the discrete return point clouds and derived digital elevation (DEM) and canopy height models (CHM). A decision tree classification algorithm is run using R package "rpart". A main goal of the project is to relate the LiDAR metrics used by the decision tree to direct canopy structural quantities. For instance, the canopy 75th minus the 50th percentile height in the LiDAR point clouds are related to the uniformity and light penetration in the upper canopy. A prototype of the decision tree achieved a classification accuracy of 89% on the training data itself, suggesting that some locations in different FNAI vegetation communities have similar structure and could not be distinguished in the LiDAR metrics used. An improved decision tree is currently under development which will include more training locations and more LiDAR metrics as input features. Results from this improved model will be presenting using the NEON ground truth locations as an independent and quantitative validation measure of the decision tree

  19. Prenatal Exposure to Cadmium, Placental Permeability and Birth Outcomes in Coastal Populations of South Africa

    PubMed Central

    Röllin, Halina B.; Kootbodien, Tahira; Channa, Kalavati; Odland, Jon Ø.

    2015-01-01

    Background The impact of prenatal exposure to cadmium (Cd) on birth outcomes is an area of concern. This study aimed to assess an impact of prenatal Cd exposure on birth outcomes in distinct coastal populations of South Africa. Methods Cadmium was measured in maternal blood (CdB) (n = 641), cord blood and in maternal urine (n = 317). This investigation assessed the associations between CdB (non-transformed) and birth outcomes across the 25th, 50th, and 75th percentile for birth weight, birth length and head circumference, to test for a linear trend. Associations between natural log-transformed maternal CdB, size at birth and other factors were further evaluated using linear mixed-effects modelling with random intercepts. Results The average gestational age in the total sample was 38 weeks; 47% of neonates were female, average birth weight was 3065 g and 11% were of low birth weight (< 2500 g). The geometric mean (GM) of the maternal CdB level was 0.25 μg/L (n = 641; 95% CI, 0.23–0.27). The cord blood Cd level was 0.27 μg/L (n = 317; 95% CI, 0.26–0.29) and urine (creatinine-corrected) Cd level was 0.27 μg/L (n = 318; 95% CI, 0.24–0.29). The CdB cord:maternal ratio in the sub-cohort was 1, suggesting that the placenta offers no protective mechanism to the foetus. An inverse association was found between CdB and the lower birth weight percentile in female neonates only (β = - 0.13, p = 0.047). Mothers who reported eating vine vegetables daily had lower levels of CdB (β = - 0.55, p = 0.025). Maternal smoking was associated with an elevation in natural log-transformed CdB levels in both male and female cohorts. Discussion Significant inverse associations between prenatal Cd exposure and birth anthropometry were found in female neonates but not in male neonates, suggesting potential sex differences in the toxico-kinetics and toxico-dynamics of Cd. PMID:26544567

  20. Statistical analysis and mapping of water levels in the Biscayne aquifer, water conservation areas, and Everglades National Park, Miami-Dade County, Florida, 2000–2009

    USGS Publications Warehouse

    Prinos, Scott T.; Dixon, Joann F.

    2016-01-01

    Maps were created by importing site coordinates, summary water-level statistics, and completeness of record statistics into a geographic information system, and by interpolating between water levels at monitoring sites in the canals and water levels along the coastline. Raster surfaces were created from these data by using the triangular irregular network interpolation method. The raster surfaces were contoured by using geographic information system software. These contours were imprecise in some areas because the software could not fully evaluate the hydrology given available information; therefore, contours were manually modified where necessary. The ability to evaluate differences in water levels between 1990–1999 and 2000–2009 is limited in some areas because most of the monitoring sites did not have 80 percent complete records for one or both of these periods. The quality of the analyses was limited by (1) deficiencies in spatial coverage; (2) the combination of pre- and post-construction water levels in areas where canals, levees, retention basins, detention basins, or water-control structures were installed or removed; (3) an inability to address the potential effects of the vertical hydraulic head gradient on water levels in wells of different depths; and (4) an inability to correct for the differences between daily water-level statistics. Contours are dashed in areas where the locations of contours have been approximated because of the uncertainty caused by these limitations. Although the ability of the maps to depict differences in water levels between 1990–1999 and 2000–2009 was limited by missing data, results indicate that near the coast water levels were generally higher in May during 2000–2009 than during 1990–1999; and that inland water levels were generally lower during 2000–2009 than during 1990–1999. Generally, the 25th, 50th, and 75th percentiles of water levels from all months were also higher near the coast and lower inland

  1. The Many Worlds of Leo Szilard: Physicist, Peacemaker, Provocateur

    NASA Astrophysics Data System (ADS)

    Lanouette, William

    2014-03-01

    Andrei Sakharov to the heroic political activism that earned him the Nobel Peace Prize. This year marks the 50th anniversary of Szilard's death, and the 75th anniversary of the Einstein letter. This talk will discuss other notable events in Szilard's life as well.

  2. An analysis of potential water availability from the Charles Mill, Clendening, Piedmont, Pleasant Hill, Senecaville, and Wills Creek Lakes in the Muskingum River Watershed, Ohio

    USGS Publications Warehouse

    Koltun, G.F.

    2014-01-01

    This report presents the results of a study to assess potential water availability from the Charles Mill, Clendening, Piedmont, Pleasant Hill, Senecaville, and Wills Creek Lakes, located within the Muskingum River Watershed, Ohio. The assessment was based on the criterion that water withdrawals should not appreciably affect maintenance of recreation-season pool levels in current use. To facilitate and simplify the assessment, it was assumed that historical lake operations were successful in maintaining seasonal pool levels, and that any discharges from lakes constituted either water that was discharged to prevent exceeding seasonal pool levels or discharges intended to meet minimum in-stream flow targets downstream from the lakes. It further was assumed that the volume of water discharged in excess of the minimum in-stream flow target is available for use without negatively impacting seasonal pool levels or downstream water uses and that all or part of it is subject to withdrawal. Historical daily outflow data for the lakes were used to determine the quantity of water that potentially could be withdrawn and the resulting quantity of water that would flow downstream (referred to as “flow-by”) on a daily basis as a function of all combinations of three hypothetical target minimum flow-by amounts (1, 2, and 3 times current minimum in-stream flow targets) and three pumping capacities (1, 2, and 3 million gallons per day). Using both U.S. Geological Survey streamgage data (where available) and lake-outflow data provided by the U.S. Army Corps of Engineers resulted in analytical periods ranging from 51 calendar years for Charles Mill, Clendening, and Piedmont Lakes to 74 calendar years for Pleasant Hill, Senecaville, and Wills Creek Lakes. The observed outflow time series and the computed time series of daily flow-by amounts and potential withdrawals were analyzed to compute and report order statistics (95th, 75th, 50th, 25th, 10th, and 5th percentiles) and means for

  3. Nonylphenol in pregnant women and their matching fetuses: Placental transfer and potential risks of infants

    SciTech Connect

    Huang, Yu-Fang; Wang, Pei-Wei; Huang, Li-Wei; Yang, Winnie; Yu, Ching-Jung; Yang, Shang-Han; Chiu, Hsin-Hao; Chen, Mei-Lien

    2014-10-15

    As the predominant environmental biodegradation product of nonylphenol (NP) ethoxylates and with proven estrogenic effects, NP is formed during the alkylation process of phenols. The purposes of this study were (1) to examine maternal and prenatal exposure to NP in Taiwan, (2) to determine the level of placental protection against NP exposure as well as the level of NP in breast milk, and (3) to assess the potential risk for breastfed newborns exposed to NP through the milk. Thirty pairs of maternal and fetal blood samples, placenta, and breast milk during the 1st and the 3rd months of lactation were collected. External NP exposures of these specimens were then analyzed by using high-performance liquid chromatography coupling with fluorescence detection. Next, the socio-demographics, lifestyle, delivery method, dietary and work history were collected using a questionnaire. In addition, the daily intake of NP from consuming breast milk in the 1st and 3rd months for newborns was studied through deterministic and probabilistic risk assessment methods. The geometric means and geometric standard deviation of NP levels in maternal blood, fetal cord blood, placenta, and breast milk in the 1st and 3rd months were 14.6 (1.7) ng/ml, 18.8 (1.8) ng/ml, 19.8 (1.9) ng/g, 23.5 (3.2) ng/ml, and 57.3 (1.4) ng/ml, respectively. The probabilistic percentiles (50th, 75th, and 95th) of daily intake NP in breast milk were 4.33, 7.79, and 18.39 μg/kg-bw/day in the 1st month, respectively, and were 8.11, 10.78, 16.08 μg/kg-bw/day in the 3rd month, respectively. The probabilistic distributions (5th, 25th, and 50th) of risk for infants aged 1 month old were 0.27, 0.64, and 1.15, respectively, and that for infants aged 3 month old were 0.31, 0.46, and 0.62, respectively. Through repeated exposure from the dietary intake of expectant mothers, fetuses could encounter a high NP exposure level due to transplacental absorption, partitioning between the maternal and fetal compartments. Daily NP

  4. An analysis of potential water availability from the Atwood, Leesville, and Tappan Lakes in the Muskingum River Watershed, Ohio

    USGS Publications Warehouse

    Koltun, G.F.

    2013-01-01

    This report presents the results of a study to assess potential water availability from the Atwood, Leesville, and Tappan Lakes, located within the Muskingum River Watershed, Ohio. The assessment was based on the criterion that water withdrawals should not appreciably affect maintenance of recreation-season pool levels in current use. To facilitate and simplify the assessment, it was assumed that historical lake operations were successful in maintaining seasonal pool levels, and that any discharges from lakes constituted either water that was discharged to prevent exceeding seasonal pool levels or discharges intended to meet minimum in-stream flow targets downstream from the lakes. It further was assumed that the volume of water discharged in excess of the minimum in-stream flow target is available for use without negatively impacting seasonal pool levels or downstream water uses and that all or part of it is subject to withdrawal. Historical daily outflow data for the lakes were used to determine the quantity of water that potentially could be withdrawn and the resulting quantity of water that would flow downstream (referred to as “flow-by”) on a daily basis as a function of all combinations of three hypothetical target minimum flow-by amounts (1, 2, and 3 times current minimum in-stream flow targets) and three pumping capacities (1, 2, and 3 million gallons per day). Using both U.S. Geological Survey streamgage data and lake-outflow data provided by the U.S. Army Corps of Engineers resulted in analytical periods ranging from 51 calendar years for the Atwood Lake to 73 calendar years for the Leesville and Tappan Lakes. The observed outflow time series and the computed time series of daily flow-by amounts and potential withdrawals were analyzed to compute and report order statistics (95th, 75th, 50th, 25th, 10th, and 5th percentiles) and means for the analytical period, in aggregate, and broken down by calendar month. In addition, surplus-water mass curve data

  5. Sonographic Measurement of the Umbilical Cord and Its Vessels and Their Relation with Fetal Anthropometric Measurements

    PubMed Central

    Rostamzadeh, Sheida; Kalantari, Mojgan; Shahriari, Mona; Shakiba, Madjid

    2015-01-01

    Background: It has been established that presence of lean umbilical cord with reduced Wharton’s jelly in sonographic scans is a fetal marker for risk of small for gestational age at birth. With improvement of ultrasound techniques, more studies have been investigating the alterations of the umbilical cord on pregnancy outcomes. Objectives: To determine the reference ranges of the umbilical cord area during pregnancy and to find out the association between umbilical cord morphometry and fetal anthropometric measurements. Patients and Methods: A cross sectional study was carried out on a study population of 278 low-risk pregnant women between 15 and 41 weeks of gestational age. Fetal anthropometric measurements including biparietal diameter, abdominal circumference, and femur length were calculated. The measurements of the cross-sectional area (CSA) and circumference of the umbilical cord, vein and arteries were done on an adjacent plane to the insertion of umbilical cord into the fetus’s abdomen. The mean and standard deviation of the CSA of the umbilical cord and the 5th, 10th, 50th, 90th, 95th percentiles of it were calculated for each gestational age. Pearson correlation coefficient was used to assess the correlation between the measures of the cord and fetal anthropometric measurements. Polynomial regression analysis was performed for curves. Results: The values of the CSA of the umbilical cord, umbilical vein and Wharton’s jelly (WJ) increase consistently until 30 weeks of gestation, after which they reach a plateau. There was a significant correlation between anthropometric measurements and umbilical cord measurements especially with the CSA of the umbilical cord, umbilical vein and WJ. The regression equation for the umbilical cord CSA according to gestational age up to 30 weeks was y = -0.2159 x2 + 23.828x-325.59 (R2 = 0.6334) and for the WJ area according to gestational age up to 30 weeks, it was y = -0.2124 x 2 +17.613x-221.66 (R2 = 0

  6. Removal of phosphorus from wastewaters using ferrous salts - a pilot scale membrane bioreactor study.

    PubMed

    Wang, Yuan; Tng, K Han; Wu, Hao; Leslie, Greg; Waite, T David

    2014-06-15

    A pilot scale membrane bioreactor (3.7 m(3)/day capacity), configured for alternate point ferrous sulphate addition, was evaluated in a fourteen month trial to comply with an effluent discharge requirement of less than 0.15 mg-P/L at the 50(th) percentile and less than 0.30 mg-P/L at the 90th percentile. Ferrous sulphate was added at a molar ratio (Fe(II):PO4) of 2.99 in the filtration chamber for 85 days and 2.60 in the primary anoxic zone for 111 days. Addition of ferrous salts to the anoxic zone achieved a final effluent phosphorous concentration (mg-P/L) of <0.05 (29%), <0.15 (77%) and <0.30 (95%), while addition of ferrous salts in the filtration zone achieved <0.05 (18%), <0.15 (63%) and <0.30 (95%). Analysis of the concentration of iron(II) in the supernatant indicated that phosphorus was mainly removed via adsorption to amorphous iron oxyhydroxides particles in both dosing scenarios. However, analysis of residence time distribution (RTD) data of the reactor indicated that severe short-circuiting from the dosing point to the membrane outlet could occur when the ferrous salts were added to the membrane zone while the reactor behaved close to a completely mixed reactor when dosing to the primary anoxic zone, resulting in improved phosphorus removal. The addition of ferrous salt was also found to delay the onset of severe increase in trans-membrane pressure as a result of the removal of macro-molecules. However, detailed analysis of the form and concentration of iron species in the supernatant and permeate indicated that the presence of fine iron particles resulted in a higher fouling rate when Fe(II) was added to the membrane zone rather than the primary anoxic zone and could cause more severe irreversible fouling in long-term operation. PMID:24709534

  7. Predicting blood lead concentrations from lead in environmental media.

    PubMed Central

    Mahaffey, K R

    1998-01-01

    Policy statements providing health and environmental criteria for blood lead (PbB) often give recommendations on an acceptable distribution of PbB concentrations. Such statements may recommend distributions of PbB concentrations including an upper range (e.g., maximum and/or 90th percentile values) and central tendency (e.g., mean and/or 50th percentile) of the PbB distribution. Two major, and fundamentally dissimilar, methods to predict the distribution of PbB are currently in use: statistical analyses of epidemiologic data, and application of biokinetic models to environmental lead measurements to predict PbB. Although biokinetic models may include a parameter to predict contribution of lead from bone (PbBone), contemporary data based on chemical analyses of pediatric bone samples are rare. Dramatic decreases in environmental lead exposures over the past 15 years make questionable use of earlier data on PbBone concentrations to estimate a contribution of lead from bone; often used by physiologic modelers to predict PbB. X-ray fluorescent techniques estimating PbBone typically have an instrument-based quantitation limit that is too high for use with many young children. While these quantitation limits have improved during the late 1990s, PbBone estimates using an epidemiologic approach to describing these limits for general populations of children may generate values lower than the instrument's quantitation limit. Additional problems that occur if predicting PbB from environmental lead by biokinetic modeling include a) uncertainty regarding the fractional lead absorption by young children; b) questions of bioavailability of specific environmental sources of lead; and c) variability in fractional absorption values over a range of exposures. Additional sources of variability in lead exposures that affect predictions of PbB from models include differences in the prevalence of such child behaviors as intensity of hand-to-mouth activity and pica. In contrast with these

  8. Synoptic climatology of winter intense precipitation events along the Mediterranean coasts

    NASA Astrophysics Data System (ADS)

    Reale, M.; Lionello, P.

    2013-07-01

    The link between winter (December-January-February) precipitation events at 15 Mediterranean coastal locations and synoptic features (cyclones and Northern Hemisphere teleconnection patterns) is analyzed. A list of precipitation events has been produced; q percentile thresholds (Thq) and corresponding frequency Nq (for q equal to 25, 50, 90 and 98) have been considered. A negative trend has been detected in total precipitation and N50 at many locations, while no significant trend in N25, N90 and N98 has been found. The negative phase of the North Atlantic Oscillation (NAO) and the East Atlantic/West Russia pattern (EAWR) compete for exerting the largest influence on the frequency of the 25th, 50th and 90th percentiles, with EAWR and NAO exerting their largest influence in the central and western Mediterranean areas, respectively. All percentiles show a similar behavior except for the 98th percentile, which shows no convincing link to any teleconnection pattern. The cyclone tracks that are associated with precipitation events have been selected using the ERA-40 reanalysis data, and a strong link between intense precipitation and cyclones is shown for all stations. In general, the probability of detecting a cyclone within a distance of 20° from each station increases with the intensity of the precipitation event and decreases with the duration of a dry period. The origin and track of cyclones producing intense precipitation differ among different areas. When precipitation occurs in the northwestern Mediterranean, cyclones are generally either of Atlantic origin or secondary cyclones associated with the passage of major cyclones north of the Mediterranean Basin, while they are mostly generated inside the region itself for events at the eastern Mediterranean coast. An important fraction of intense events in the southern areas is produced by cyclones that are generated over northern Africa. The analysis of sea level pressure and geopotential height at 500 h

  9. Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations

    SciTech Connect

    Al-Subeihi, Ala' A.A.; Alhusainy, Wasma; Kiwamoto, Reiko; Spenkelink, Bert; Bladeren, Peter J. van; Rietjens, Ivonne M.C.M.; Punt, Ans

    2015-03-01

    The present study aims at predicting the level of formation of the ultimate carcinogenic metabolite of methyleugenol, 1′-sulfooxymethyleugenol, in the human population by taking variability in key bioactivation and detoxification reactions into account using Monte Carlo simulations. Depending on the metabolic route, variation was simulated based on kinetic constants obtained from incubations with a range of individual human liver fractions or by combining kinetic constants obtained for specific isoenzymes with literature reported human variation in the activity of these enzymes. The results of the study indicate that formation of 1′-sulfooxymethyleugenol is predominantly affected by variation in i) P450 1A2-catalyzed bioactivation of methyleugenol to 1′-hydroxymethyleugenol, ii) P450 2B6-catalyzed epoxidation of methyleugenol, iii) the apparent kinetic constants for oxidation of 1′-hydroxymethyleugenol, and iv) the apparent kinetic constants for sulfation of 1′-hydroxymethyleugenol. Based on the Monte Carlo simulations a so-called chemical-specific adjustment factor (CSAF) for intraspecies variation could be derived by dividing different percentiles by the 50th percentile of the predicted population distribution for 1′-sulfooxymethyleugenol formation. The obtained CSAF value at the 90th percentile was 3.2, indicating that the default uncertainty factor of 3.16 for human variability in kinetics may adequately cover the variation within 90% of the population. Covering 99% of the population requires a larger uncertainty factor of 6.4. In conclusion, the results showed that adequate predictions on interindividual human variation can be made with Monte Carlo-based PBK modeling. For methyleugenol this variation was observed to be in line with the default variation generally assumed in risk assessment. - Highlights: • Interindividual human differences in methyleugenol bioactivation were simulated. • This was done using in vitro incubations, PBK modeling

  10. Discovered and undiscovered gold endowment of Turkey: a quantitative mineral resource assessment using GIS and rank statistical analysis

    NASA Astrophysics Data System (ADS)

    Yigit, Ozcan

    2012-06-01

    An assessment of the discovered and undiscovered gold endowment of Turkey, a prolific sector in the Tethyan Metallogenic Belt, is developed from a comprehensive Geographic Information System database containing 402 gold deposits and prospects. The majority of the gold deposits and prospects are epithermal, porphyry, volcanic-associated massive sulfides, orogenic gold, and skarn systems. These five major deposit types form more than 90% of the known gold deposits and prospects. Just 87, corresponding to 21.6%, of the deposits and prospects in the data set have current calculated gold reserve and/or resources, containing a total of 54.885 Moz Au. Current gold reserves of the country are 21.447 Moz constituting 39.1% of the total gold resources, of which 17.1 Moz gold are contained in four deposits. Out of these 87 deposits and prospects, only 27 contain significant gold reserve and/or resources (defined as equal to or more than 0.32 Moz or 10 tons Au), and contain 91.8% of the total gold endowment of the country. The cumulative frequency distribution model of the gold endowment of Turkey abides by log-normal distribution. Observed and estimated 10th, 50th (median), and 90th percentiles of the data are 0.0046 Moz [0.0045 Moz estimated], 0.1030 Moz [0.0875 Moz], and 1.4969 Moz [1.6938 Moz], respectively. The 99th percentile of the data is 7.6444 Moz [18.9636 Moz]. The arithmetic mean of the known gold endowment is 0.657 Moz and the Swanson mean size is 0.492 Moz. The arithmetic mean of the 27 significant gold deposit or prospects is 1.94 Moz. Zipf's law estimates of the undiscovered (residual) gold resources of Turkey are based on the current size of the largest, rank 1, gold deposit of Turkey, which is the Kisladag porphyry deposit that has 17.481 Moz gold endowment (including past production). Zipf's law estimates a total of 88.261 Moz natural or total gold endowment, 57.133 Moz or 65% of which has already been found. This predicts at least 31.128 Moz residual or

  11. Dietary vitamin D₂--a potentially underestimated contributor to vitamin D nutritional status of adults?

    PubMed

    Cashman, Kevin D; Kinsella, Michael; McNulty, Breige A; Walton, Janette; Gibney, Michael J; Flynn, Albert; Kiely, Mairead

    2014-07-28

    It has been suggested that vitamin D₂ is not very prevalent in the human food chain. However, data from a number of recent intervention studies suggest that the majority of subjects had measurable serum 25-hydroxyvitamin D₂ (25(OH)D₂) concentrations. Serum 25(OH)D₂, unlike 25(OH)D₃, is not directly influenced by exposure of skin to sun and thus has dietary origins; however, quantifying dietary vitamin D₂ is difficult due to the limitations of food composition data. Therefore, the present study aimed to characterise serum 25(OH)D₂ concentrations in the participants of the National Adult Nutrition Survey (NANS) in Ireland, and to use these serum concentrations to estimate the intake of vitamin D₂ using a mathematical modelling approach. Serum 25(OH)D₂ concentration was measured by a liquid chromatography-tandem MS method, and information on diet as well as subject characteristics was obtained from the NANS. Of these participants, 78.7 % (n 884) had serum 25(OH)D₂ concentrations above the limit of quantification, and the mean, maximum, 10th, 50th (median) and 90th percentile values of serum 25(OH)D₂ concentrations were 3.69, 27.6, 1.71, 2.96 and 6.36 nmol/l, respectively. To approximate the intake of vitamin D₂ from these serum 25(OH)D₂ concentrations, we used recently published data on the relationship between vitamin D intake and the responses of serum 25(OH)D concentrations. The projected 5th to 95th percentile intakes of vitamin D₂ for adults were in the range of 0.9-1.2 and 5-6 μg/d, respectively, and the median intake ranged from 1.7 to 2.3 μg/d. In conclusion, the present data demonstrate that 25(OH)D₂ concentrations are present in the sera of adults from this nationally representative sample. Vitamin D₂ may have an impact on nutritional adequacy at a population level and thus warrants further investigation. PMID:24780068

  12. ACS Magazine Cover Candidates

    NASA Technical Reports Server (NTRS)

    1988-01-01

    New cockpit displays make use of cathode-ray-tube (CRT) technology, the method used to create images on TVs and computer screens. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 113), by James Schultz.

  13. 50 CFR 91.12 - Contest eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) MISCELLANEOUS PROVISIONS MIGRATORY BIRD HUNTING AND CONSERVATION STAMP CONTEST Procedures for Entering the... to submit an entry in the current year's contest. For the 75th contest (2007) only, any artist,...

  14. Tomato seeds for LDEF

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Tomato seeds are prepared for their launch aboard the Langley's Long Duration Exposure Facility. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 119), by James Schultz.

  15. Shark Scales

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Mother Nature's riblet, this shark's dermal denticle has been magnified 3,000 times. Photograph and caption published in Winds of Change, 75th Anniversary NASA publication (page 123), by James Schultz.

  16. P-47 Thunderbolt with dive recovery flaps

    NASA Technical Reports Server (NTRS)

    1946-01-01

    Caption: 'The dive recovery flaps on this P-47 Thunderbolt are barely visible underneath the wings. Photograph and caption published in Winds of Change, 75th Anniversary NASA publication (pages 52-53 and 130), by James Schultz.

  17. 75 FR 25309 - Environmental Impact Statement: Cook County, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... TRANSPORTATION Federal Highway Administration Environmental Impact Statement: Cook County, IL AGENCY: Federal... advise the public that an Environmental Impact Statement (EIS) will be prepared for the 75th Street... impacts are anticipated. Potential impacts may include residential relocations, effects on...

  18. Advanced Canard in 12 Foot Tunnel

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Advanced-concepts model plane with front canards, winglets and pusher propellers, in 12 Foot Low-Speed Tunnel. Photograph published in Winds of Change, 75th Anniversary NASA publication, (page 12), by James Schultz.

  19. Human Computers 1947

    NASA Technical Reports Server (NTRS)

    1947-01-01

    Langley's human computers at work in 1947. The female presence at Langley, who performed mathematical computations for male staff. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 48), by James Schultz.

  20. 49 CFR 571.202a - Standard No. 202a; Head restraints; Mandatory applicability begins on September 1, 2009.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... position incapable of seating a 50th percentile male Hybrid III test dummy specified in 49 CFR part 572... torso of the 50th percentile male Hybrid III test dummy specified in 49 CFR part 572, subpart E, fitted... percentile female Hybrid III test dummy specified in 49 CFR part 572, subpart O is positioned according to...

  1. 49 CFR 571.202a - Standard No. 202a; Head restraints; Mandatory applicability begins on September 1, 2009.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... position incapable of seating a 50th percentile male Hybrid III test dummy specified in 49 CFR part 572... torso of the 50th percentile male Hybrid III test dummy specified in 49 CFR part 572, subpart E, fitted... percentile female Hybrid III test dummy specified in 49 CFR part 572, subpart O is positioned according to...

  2. The President's Challenge Physical Fitness Program Packet, 1997-98.

    ERIC Educational Resources Information Center

    President's Council on Physical Fitness and Sports, Washington, DC.

    The President's Challenge Physical Fitness Awards Program makes four awards: The Presidential Physical Fitness Award recognizes those students who score at or about the 85th percentile on all five tests; the National Physical Fitness Award for those in the 50th to 84th percentile; the Participant Award for those who fall below the 50th percentile…

  3. Celebrating 50 Years!

    ERIC Educational Resources Information Center

    Kristjansdottir, Anna

    2011-01-01

    The author congratulates members of the Association of Teachers of Mathematics (ATM) on celebrating the 50th anniversary of their annual conference. These conferences have kept the spirit alive from the early years, especially the engagement in investigative, collaborative, and reasoning activities. In the 50th year as an association, the author…

  4. Nutrient and chlorophyll relations in selected streams of the New England Coastal Basins in Massachusetts and New Hampshire, June-September 2001

    USGS Publications Warehouse

    Riskin, Melissa L.; Deacon, J.R.; Liebman, M.L.; Robinson, K.W.

    2003-01-01

    study exceeded the preliminary U.S. Environmental Protection Agency nutrient criteria values for the coastal region of New England. In an effort to establish more appropriate nutrient and chlorophyll criteria for streams in the New England coastal region, relations between total nitrogen and total phosphorus to periphyton chlorophyll a in wadeable streams from this study were quantified to present potential techniques for determining nutrient concentrations. Linear regression was used to estimate the total nitrogen and total phosphorus concentrations that corresponded to various chlorophyll a concentrations. On the basis of this relation, a median concentration for moderately enriched streams of 21 milligrams per square meter (mg/m2) of periphyton chlorophyll a from the literature corresponded to estimated concentrations of 1.3 milligrams per liter (mg/L) for total nitrogen and 0.12 mg/L for total phosphorus. The median concentration for periphyton chlorophyll a from the literature is similar to the 50th-percentile concentration of periphyton chlorophyll a (17 mg/m2) calculated with the data from open-canopy sites in this study. The 25th-percentile concentration for periphyton chlorophyll a of all open-canopy sites (5.2 mg/m2) and the 75th-percentile concentration for periphyton chlorophyll a of open-canopy reference sites (16 mg/m2) also were plotted to provide additional estimates and methods for developing total nitrogen and total phosphorus criteria. The 25th-percentile concentrations of total nitrogen and total phosphorus were calculated based on all sites in this study and were used as another potential criteria estimation. A concentration of 0.64 mg/L for total nitrogen and 0.030 mg/L for total phosphorus were calculated. As another possible method to develop threshold concentrations, the 10th-percentile concentrations of total nitrogen and total phosphorus were calculated based on all the impaired sites in this study. A concentration threshold of 0

  5. Too old to have children? Lessons from natural fertility populations

    PubMed Central

    Eijkemans, Marinus J.C.; van Poppel, Frans; Habbema, Dik F.; Smith, Ken R.; Leridon, Henri; te Velde, Egbert R.

    2014-01-01

    STUDY QUESTION Is it possible to construct an age curve denoting the ages above which women are biologically too old to reproduce? SUMMARY ANSWER We constructed a curve based on the distribution of female age at last birth in natural fertility populations reflecting the ages above which women have become biologically too old to have children. WHAT IS KNOWN ALREADY The median age at last birth (ALB) for females is ∼40–41 years of age across a range of natural fertility populations. This suggests that there is a fairly universal pattern of age-related fertility decline. However, little is known about the distribution of female ALB and in the present era of modern birth control, it is impossible to assess the age-specific distribution of ALB. Reliable information is lacking that could benefit couples who envisage delaying childbearing. STUDY DESIGN, SIZE, DURATION This study is a review of high-quality historical data sets of natural fertility populations in which the distributions of female age at last birth were analysed. The studies selected used a retrospective cohort design where women were followed as they age through their reproductive years. PARTICIPANTS/MATERIALS, SETTING, METHODS Using a common set of eligibility criteria, large data files of natural fertility populations were prepared such that the analysis could be performed in parallel across all populations. Data on the ALB and confounding variables are presented as box and whisker plots denoting the 5th, 25th, 50th, 75th and 95th percentile distribution of the age at last birth for each population. The analysis includes the estimation of Kaplan–Meier curves for age at last birth of each population. The hazard curve for ALB was obtained by plotting the smoothed hazard curve of each population and taking the lowest hazard within a time period of at least 5 years. This lowest hazard curve was then transformed into a cumulative distribution function representing the composite curve of the end of

  6. Plasma cholesterol and other cardiac risk factors in adolescent girls.

    PubMed Central

    Bermingham, M A; Jones, E; Steinbeck, K; Brock, K

    1995-01-01

    The aim was to examine the effects of smoking, physical activity, and body mass on total cholesterol and high density lipoprotein cholesterol (HDL-C) in adolescent schoolgirls in Sydney, Australia. Body mass index (BMI) and waist to hip ratio (WHR) were determined in 144 girls aged 15 to 18 years. Total cholesterol (TC) and HDL-C were estimated on fingerprick blood and behavioural variables assessed by questionnaire. Prevalence of overweight (> 90th centile for BMI) was less in Australian adolescents than reported from the USA. Smokers had lower total cholesterol than non-smokers; this was partly explained by a lower HDL-C in the smokers. Physical activity was associated with a less atherogenic TC/HDL-C ratio. Girls with BMI > 90th centile had higher mean TC/HDL-C and apoprotein B than the group as a whole but those > 90th centile for WHR did not. PMID:8554353

  7. Gene Cernan on Apollo 17

    NASA Video Gallery

    Apollo 17 Commander Gene Cernan recalls fixing a lunar rover problem with duct tape during his December 1972 mission. Cernan's interview was part of the commemoration of NASA's 50th anniversary in ...

  8. Benito Perez Galdos: A Selected Annotated Bibliography

    ERIC Educational Resources Information Center

    Woodbridge, Hensley C.

    1970-01-01

    Special issue devoted to works and criticisms of Benito Perez Galdos on the occasion of the 50th anniversary of the Spanish author's death. First time that "Hispania" has dedicated an entire issue to one author. (DS)

  9. 49 CFR 572.5 - General description.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES 50th Percentile Male § 572... motion and also under crash impact conditions there is no contact between metallic elements except...

  10. 49 CFR Appendix A to Subpart U of... - Figures

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES ES-2re Side Impact Crash Test Dummy, 50th Percentile Adult Male Pt. 572, Subpt. U, App. A Appendix A to Subpart U of Part...

  11. 49 CFR 572.5 - General description.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES 50th Percentile Male § 572... motion and also under crash impact conditions there is no contact between metallic elements except...

  12. 49 CFR 572.5 - General description.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES 50th Percentile Male § 572... motion and also under crash impact conditions there is no contact between metallic elements except...

  13. 49 CFR Appendix A to Subpart U of... - Figures

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES 2re Side Impact Crash Test Dummy, 50th Percentile Adult Male Instrumentation and test conditions. Pt. 572, Subpt. U, App....

  14. 49 CFR Appendix A to Subpart U of... - Figures

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES ES-2re Side Impact Crash Test Dummy, 50th Percentile Adult Male Pt. 572, Subpt. U, App. A Appendix A to Subpart U of Part...

  15. 49 CFR Appendix A to Subpart U of... - Figures

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ANTHROPOMORPHIC TEST DEVICES 2re Side Impact Crash Test Dummy, 50th Percentile Adult Male Instrumentation and test conditions. Pt. 572, Subpt. U, App....

  16. Conjucion y divergencia de vida y arte en Galdos (The Similarity and Diversity of Life and Art in Galdos)

    ERIC Educational Resources Information Center

    Casalduero, Joaquin

    1970-01-01

    Special issue devoted to works and criticisms of Benito Perez Galdos on the occasion of the 50th anniversary of the Spanish author's death. First time that Hispania" has dedicated an entire issue to one author. (DS)

  17. Marshall Space Flight Center: 50 Years, 50 Seconds

    NASA Video Gallery

    Talk about time flying! Take a look at this super-fast review of highlights from the past 50 years at the Marshall Center. This year, Marshall is celebrating its 50th anniversary, highlighting its ...

  18. Carl Sagan Cosmos Voyager

    NASA Video Gallery

    Excerpt from "Cosmos", read by Carl Sagan, part of the NASA.gov multimedia piece celebrating NASA's 50th anniversary in 2008. Used by permission of Carl Sagan Associates. To see the whole interacti...

  19. Faces of Marshall: Sam Ortega

    NASA Video Gallery

    Several Marshall employees were interviewed as part of Marshall's 50th Anniversary activities. Engineer Sam Ortega tells his story of how he came to work as an engineer at Marshall and how sewing a...

  20. Faces of Marshall: Erika Andrews

    NASA Video Gallery

    Several Marshall employees were interviewed as part of Marshall's 50th Anniversary activities. Human Resources Specialist Erika Andrews tells how she came to work at NASA as a specialist in organiz...

  1. Rise: Surviving and Thriving after Trauma Williams Sian Rise: Surviving and Thriving after Trauma 336pp £18.99 Orion Books 9781474602686 1474602681 [Formula: see text].

    PubMed

    2016-08-10

    Tears, sadness, love and laughter are intertwined in this moving book, detailing the journey of Sian Williams who was diagnosed with breast cancer just after her 50th birthday - resulting in a double mastectomy. PMID:27507386

  2. Cincinnati; Our Convention City

    ERIC Educational Resources Information Center

    Borchin, Anna

    1970-01-01

    During Easter week, 1971, Cincinnati will be the hostess of the 50th anniversary convention of the Catholic Library Association. Items of historical interest concerning the city are briefly described. (NH)

  3. Silicon Solar Cell Turns 50

    SciTech Connect

    Perlin, J.

    2004-08-01

    This short brochure describes a milestone in solar (or photovoltaic, PV) research-namely, the 50th anniversary of the invention of the first viable silicon solar cell by three researchers at Bell Laboratories.

  4. The Next 'Moon Shot' Moment

    NASA Video Gallery

    For the 50th anniversary of President Kennedy's speech to Congress, when he challenged our nation to land a man on the moon and return him safely to Earth, five NASA Langley employees answered the ...

  5. NASA Beams Beatles Song to Space

    NASA Video Gallery

    The transmission over NASA's Deep Space Network will commemorate the 40th anniversary of the day The Beatles recorded the song, as well as the 50th anniversary of NASA's founding and the group's be...

  6. 76 FR 18778 - Cape Cod National Seashore; South Wellfleet, MA; Cape Cod National Seashore Advisory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... topics--shoreline change Climate Friendly Park program update 50th Anniversary 6. Old Business 7. New... Shacks Improved Properties/Town Bylaws Herring River Wetland Restoration Wind Turbines/Cell...

  7. 76 FR 44606 - Cape Cod National Seashore; South Wellfleet, MA; Cape Cod National Seashore Advisory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... change, Climate Friendly Park program update, 50th Anniversary. 6. Old Business. 7. New Business. 8. Date... Properties/Town Bylaws, Herring River Wetland Restoration, Wind Turbines/Cell Towers, Flexible...

  8. Faces of Marshall: Arthur Brown

    NASA Video Gallery

    Several Marshall employees were interviewed as part of Marshall's 50th Anniversary activities. Metallurgist Arthur Brown shares how his high school drafting and welding success led him to a NASA ca...

  9. Tradicion mistica y cervantismo en las novelas de Galdos, 1890-97 (The Traditional Mysticism and Cervantes' Influencein the novels of Galdos)

    ERIC Educational Resources Information Center

    Correa, Gustavo

    1970-01-01

    Special issue devoted to works and criticisms of Benito Perez Galdos on the occasion of the 50th anniversary of the Spanish author's death. First time that Hispania" has dedicated an entire issue to one author. (DS)

  10. Hawai'i: The Aloha State

    ERIC Educational Resources Information Center

    Klein, Edward F.

    2009-01-01

    August 21, 2009, marks the 50th anniversary of the entry of the 50th state into the United States of America. All the states have their stories, but as a string of islands in the vast Pacific Ocean, more than 2,000 miles from any other land mass, Hawai'i has a story that is unique in many ways. Consider, for example, that Hawai'i has two official…

  11. 20 CFR 704.101 - Administration; compensation districts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... extended in the following manner to include: (a) Canada, east of the 75th degree west longitude... 110th degree west longitude, is assigned to District No. 10. (c) Canada, west of the 110th degree west longitude, and all areas in the Pacific Ocean north of the 45th degree north latitude are assigned...

  12. AN INDEPENDENT STUDY PROJECT FOR GIFTED UNDERACHIEVERS. FINAL REPORT.

    ERIC Educational Resources Information Center

    PURKEY, WILLIAM WATSON

    THE STIMULATION OF BRIGHT UNDERACHIEVERS WAS THE GOAL OF A PROJECT CONDUCTED IN NINE FLORIDA HIGH SCHOOLS WITH A SAMPLE OF 44 EXPERIMENTAL AND 40 CONTROL GROUP STUDENTS. BRIGHT UNDERACHIEVERS WERE DEFINED AS STUDENTS WHO HAD SCORED ABOVE THE 75TH PERCENTILE ON THE SCHOOL AND COLLEGE ABILITY TEST IN THE NINTH GRADE, BUT WHOSE GRADES AVERAGED "C" OR…

  13. The American Academy of Kinesiology and Physical Education, 1940-1984: Innovation, Introspection, Identity, and Involvement

    ERIC Educational Resources Information Center

    Jable, J. Thomas

    2006-01-01

    In 2005, the American Academy of Kinesiology and Physical Education reached its 75th anniversary. In celebration of this momentous occasion, this paper examines 44 years of the Academy's history from 1940 to 1984. During the 1940s, the Academy was engaged in the war effort. Then in the 1950s, it sought to define more precisely its role and…

  14. Bell X-5 Model and Molds

    NASA Technical Reports Server (NTRS)

    1953-01-01

    A Langley model maker examines the molds used to form a model of the Bell X-5, a variable sweep craft that first flew in June of 1951. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 64), by James Schultz.

  15. The Writer's Digest Guide to Good Writing.

    ERIC Educational Resources Information Center

    Clark, Thomas, Ed.; And Others

    Marking "Writer's Digest"'s upcoming 75th anniversary, this book presents a collection of the best writing instruction, advice, and inspiration written by famous and not-so-famous writers and published in the magazine from the 1920s to the 1990s. The 49 selections in the book are arranged chronologically and address: (1) selecting an applying…

  16. About Those Private School Achievements.

    ERIC Educational Resources Information Center

    Bracey, Gerald W.

    1998-01-01

    According to 1996 National Assessment of Educational Progress science results, there is no difference between private and public school performance by the time one reaches the 75th percentile of grade 12. Recent SAT scores for the top 20% of students indicate teachers are not inflating grades. The National Center for Fair and Open Testing…

  17. 29 CFR 783.29 - Adoption of the exemption in the original 1938 Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... LABOR STANDARDS ACT TO EMPLOYEES EMPLOYED AS SEAMEN Legislative History and Judicial Construction of the... legislative history of the Act shows that Congress intended to exempt, as employees “employed as” seamen, only... Committee on Education and Labor and House Committee on Labor on S. 2475 and H.R. 7200, 75th Cong., 1st...

  18. The Tacoma Narrows Bridge Collapse on Film and Video

    ERIC Educational Resources Information Center

    Olson, Don; Hook, Joseph; Doescher, Russell; Wolf, Steven

    2015-01-01

    This month marks the 75th anniversary of the Tacoma Narrows Bridge collapse. During a gale on Nov. 7, 1940, the bridge exhibited remarkable oscillations before collapsing spectacularly (Figs. 1-5). Physicists over the years have spent a great deal of time and energy studying this event. By using open-source analysis tools and digitized footage of…

  19. 77 FR 16806 - Codex Alimentarius Commission: Meeting of the Codex Committee on Residues of Veterinary Drugs in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... from FAO/WHO and from the 75th Meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA... Food Safety and Inspection Service Codex Alimentarius Commission: Meeting of the Codex Committee on Residues of Veterinary Drugs in Food AGENCY: Office of the Under Secretary for Food Safety, USDA....

  20. Education for a New World, 1994.

    ERIC Educational Resources Information Center

    Institute of International Education, New York, NY.

    This annual report marks the 75th anniversary of the Institute of International Education (IIE) and describes the IIE's 1994 activities and programs. During 1994 more than 10,000 individuals studied, conducted research, received practical training, or provided international technical assistance under 248 programs IIE administered for 217 sponsors,…

  1. 29 CFR 783.29 - Adoption of the exemption in the original 1938 Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Committee on Education and Labor and House Committee on Labor on S. 2475 and H.R. 7200, 75th Cong., 1st sess... exempted for the same reason saying * * * “We feel that in a general interpretation of the whole bill that... the workers engaged in transportation by water, we feel that it may conflict with the laws now...

  2. Remnants from the Past: Using Scrapbooks to Make U.S. History Personal and Meaningful

    ERIC Educational Resources Information Center

    DeRose, John J.

    2009-01-01

    Whitefish Bay High School recently celebrated its 75th anniversary, and the author wanted his students to remember this event for many years. As a U.S. history teacher, he also wanted to find a way for them to understand that their high school's history has coincided with national events and trends over the past seven decades. He decided to use a…

  3. Expanding Access to Knowledge: Continuing Higher Education. NUCEA 1915-1990.

    ERIC Educational Resources Information Center

    Rohfeld, Rae Wahl, Ed.

    In honor of its 75th anniversary, the National University Continuing Education Association (NUCEA) presents this compendium of the history of continuing higher education. It traces the adult education movement from its beginnings and explores the role of continuing education and NUCEA in the 20th century. Articles, excerpts, and reports are…

  4. Ryan XV-5A model

    NASA Technical Reports Server (NTRS)

    1962-01-01

    The duct-fan method of propulsion which would enable aircraft to take off helicopter-like was tested with models like this one, the Ryan XV- 5A, which was built and flown at NASA Ames. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 84) and Crafting Flight (page106), by James Schultz.

  5. Brain gray and white matter differences in healthy normal weight and obese children

    Technology Transfer Automated Retrieval System (TEKTRAN)

    To compare brain gray and white matter development in healthy normal weight and obese children. Twenty-four healthy 8- to 10-year-old children whose body mass index was either <75th percentile (normal weight) or >95th percentile (obese) completed an MRI examination which included T1-weighted three-d...

  6. Full Scale Wind Tunnel and Seaplane Tow Channel

    NASA Technical Reports Server (NTRS)

    1930-01-01

    Construction progress, aerials of East Area. L5169: Langley's seaplane towing facility (right) and the Full Scale Tunnel (left) were photographed in November of 1930. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 39), by James Schultz.

  7. 42 CFR 413.106 - Reasonable cost of physical and other therapy services furnished under arrangements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR... rate based on the 75th percentile of salary ranges paid by providers in the geographical area, by type... geographical area by type of therapy. (e) Additional allowances. (1) If a therapist supervises other...

  8. 42 CFR 413.106 - Reasonable cost of physical and other therapy services furnished under arrangements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR... rate based on the 75th percentile of salary ranges paid by providers in the geographical area, by type... geographical area by type of therapy. (e) Additional allowances. (1) If a therapist supervises other...

  9. 42 CFR 413.106 - Reasonable cost of physical and other therapy services furnished under arrangements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR... rate based on the 75th percentile of salary ranges paid by providers in the geographical area, by type... geographical area by type of therapy. (e) Additional allowances. (1) If a therapist supervises other...

  10. 42 CFR 413.106 - Reasonable cost of physical and other therapy services furnished under arrangements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REIMBURSEMENT; PAYMENT FOR END-STAGE RENAL DISEASE SERVICES; OPTIONAL PROSPECTIVELY DETERMINED PAYMENT RATES FOR... rate based on the 75th percentile of salary ranges paid by providers in the geographical area, by type... geographical area by type of therapy. (e) Additional allowances. (1) If a therapist supervises other...

  11. Build a Sierpinski Pyramid.

    ERIC Educational Resources Information Center

    Kelley, Paul

    1999-01-01

    Describes an activity on fractal geometry in which students built a 19-foot-tall Sierpinski pyramid in the Minneapolis Convention Center in conjunction with the National Council of Teachers of Mathematics' (NCTM) 75th Annual Meeting in April, 1997. Contains 13 references. (ASK)

  12. Air Force Convair F-102 at Wallops

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Two models of the Air Force's Convair F-102 sit poised for launch from Langley's Wallops Island facility. The coke bottle shape of the model on the bottom follows the area rule. Photograph published in Winds of Change, 75th Anniversary NASA publication, by James Schultz (page 60).

  13. Air Force Convair F-102 at Wallops

    NASA Technical Reports Server (NTRS)

    1953-01-01

    Two models of the Air Force's Convair F-102 sit poised for launch from Langley's Wallops Island facility. The Coke Bottle shape of the model on the bottom follows the area rule. Photograph published in Winds of Change, 75th Anniversary NASA publication, (page 60), by James Schultz.

  14. Spin Effects in Hard Exclusive Electroproduction of Mesons

    NASA Astrophysics Data System (ADS)

    Kroll, P.

    In this talk various spin effects in hard exclusive electroproduction of mesons are briefly reviewed. The data are discussed in the light of recent theoretical calculations within the frame work of the handbag approach. This talk has been presented at the Conference in Honor of Prof. Anatoly Efremov's 75th Birthday held at Trento, July, 2009.

  15. Able to Play: Mobilizing Communities for Children of All Abilities - Framing the Issue. Seminar Series

    ERIC Educational Resources Information Center

    W. K. Kellogg Foundation, 2005

    2005-01-01

    "Able to Play: Mobilizing Communities for Children of All Abilities" is one of a series of six seminars that the W.K. Kellogg Foundation hosted during 2005 to celebrate its 75th Anniversary year. The seminar, held in Lansing, Michigan, June 8-10, shared the lessons learned from the Able to Play Project. Advocates for people with disabilities,…

  16. Changing Our World: "Community College Journal" Turns 75

    ERIC Educational Resources Information Center

    Community College Journal, 2005

    2005-01-01

    August 2005 marks the 75th year of production for the "Community College Journal". The mission of the journal since its founding has been to bring valuable news and information to the membership of the American Association of Community Colleges. Considering its longevity, it appears the "Community College Journal" has successfully accomplished…

  17. Dewey's "Art as Experience": The Psychological Background

    ERIC Educational Resources Information Center

    Shusterman, Richard

    2010-01-01

    The year 2009 marks the 150th anniversary of John Dewey's birth and also the 75th anniversary of the publication of his aesthetic masterpiece "Art as Experience"--a book that has been extremely influential within the field of aesthetics, not only in philosophical aesthetics and aesthetic education but also in the arts themselves. In this essay,…

  18. Horst Aspöck, encyclopedist and entomologist extraordinaire – a personal appreciation

    PubMed Central

    Ohl, Michael

    2016-01-01

    Abstract The paper provides an overview of the life and work of Prof. Dr. Horst Aspöck, the doyen of neuropterology, on the occasion of his 75th birthday. It particularly emphasizes his outstanding contributions to the development of neuropterology since the 1960s. PMID:26884700

  19. A Context for the Birth of "The Journal of Negro Education"

    ERIC Educational Resources Information Center

    Gordon, Edmund W.

    2007-01-01

    "The Journal of Negro Education" was born during the third decade of the 20th century. "The Journal" has reflected concern with race and racial discrimination as a central problem in the education of Negro people. During its 75th anniversary, the legacy of "The Journal" continues and has remained the educational, societal, and economic outlet for…

  20. Scramjet Engine in Mach 7 STF

    NASA Technical Reports Server (NTRS)

    1986-01-01

    This supersonic combustion ramjet, or scramjet, engine is put through its paces at four to seven times the speed of sound in Langley's Scramjet Test Facility. Photograph published in Winds of Change, 75th Anniversary NASA publication, (page 126), by James Schultz.

  1. 2. Historic American Buildings Survey Copied by E. W. Russell, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Copied by E. W. Russell, Photographer, August 31, 1936 75TH ANNIVERSARY YEARBOOK (NOT COPYRIGHT) - REAR OF BUILDING BEFORE REINFORCED CONCRETE BALCONIES WERE ADDED - Spring Hill College, Main Building, Old Shell Road, Spring Hill, Mobile County, AL

  2. 1. Historic American Buildings Survey Copied by E. W. Russell, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Copied by E. W. Russell, Photographer, August 31, 1936 75TH ANNIVERSARY YEARBOOK (NOT COPYRIGHT) - FRONT OF MAIN BUILDING BEFORE CLOISTER ARCADE WAS ADDED - Spring Hill College, Main Building, Old Shell Road, Spring Hill, Mobile County, AL

  3. 75 FR 29268 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ..., 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376. ] Sec. 67.4 2. The tables... Route 100/East boundary: Approximately 1,000 feet west of Southwest 75th Avenue/South boundary: Southwest 163rd Street/West boundary: Approximately 1,500 feet east of Southwest 101st Avenue. *...

  4. 29 CFR 789.0 - Introductory statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... assurance.” 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060), as amended by the Act of June 26, 1940 (Pub. Res. No. 88, 76th Cong., 3d sess., 54 Stat. 616); by Reorganization Plan No. 2 (60 Stat. 616);...

  5. 29 CFR 789.0 - Introductory statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... assurance.” 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060), as amended by the Act of June 26, 1940 (Pub. Res. No. 88, 76th Cong., 3d sess., 54 Stat. 616); by Reorganization Plan No. 2 (60 Stat. 616);...

  6. 29 CFR 789.0 - Introductory statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... assurance.” 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060), as amended by the Act of June 26, 1940 (Pub. Res. No. 88, 76th Cong., 3d sess., 54 Stat. 616); by Reorganization Plan No. 2 (60 Stat. 616);...

  7. 29 CFR 776.0a - Introductory statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Employee Coverage § 776.0a Introductory statement. (a) Scope and significance of this part. (1) The Fair... with respect to this general coverage are set forth in this part to provide “a practical guide to... of an interpretation, that it is incorrect. 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060),...

  8. 29 CFR 789.0 - Introductory statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... assurance.” 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060), as amended by the Act of June 26, 1940 (Pub. Res. No. 88, 76th Cong., 3d sess., 54 Stat. 616); by Reorganization Plan No. 2 (60 Stat. 616);...

  9. 29 CFR 776.0a - Introductory statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Employee Coverage § 776.0a Introductory statement. (a) Scope and significance of this part. (1) The Fair... with respect to this general coverage are set forth in this part to provide “a practical guide to... of an interpretation, that it is incorrect. 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060),...

  10. 29 CFR 789.0 - Introductory statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... assurance.” 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060), as amended by the Act of June 26, 1940 (Pub. Res. No. 88, 76th Cong., 3d sess., 54 Stat. 616); by Reorganization Plan No. 2 (60 Stat. 616);...

  11. 29 CFR 776.0a - Introductory statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Employee Coverage § 776.0a Introductory statement. (a) Scope and significance of this part. (1) The Fair... with respect to this general coverage are set forth in this part to provide “a practical guide to... of an interpretation, that it is incorrect. 1 Pub. L. 718, 75th Cong., 3d sess. (52 Stat. 1060),...

  12. MOSQUITO VECTOR CONTROL AND BIOLOGY IN LATIN AMERICA - A 19TH SYMPOSIUM

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 19th Annual Latin American symposium presented by the American Mosquito Control Association (AMCA) was held as part of the 75th Annual Meeting in New Orleans, LA, in April 2009. The principal objective, as for the previous 18 symposia, was to promote participation in the AMCA by vector control s...

  13. Hong Kong Student Achievement in OECD-PISA Study: Gender Differences in Science Content, Literacy Skills, and Test Item Formats

    ERIC Educational Resources Information Center

    Yip, Din Yan; Chiu, Ming Ming; Ho, Esther Sui Chu

    2004-01-01

    This study examined gender differences in students' scientific literacy as measured by OECD-PISA. In particular, we focused on the 2437 students from 140 Hong Kong schools. Hong Kong boys' and girls' science scores did not differ overall. However, boys scored higher than girls at the higher percentiles (75th and above). Moreover, specific test…

  14. The Langley Aerodrome

    NASA Technical Reports Server (NTRS)

    1990-01-01

    L90-4341: 'The Langley Aerodrome, brainchild of a group led by Samuel Langley. Shortly after this photo was taken, the December 8, 1903, manned tests of the Aerodrome ended abruptly in failure, as it fell into the Potomac River'. Photograph published in Winds of Change, 75th Anniversary NASA publication, page 6.

  15. Assessment of Local Dose Reference Values for Recanalization of Chronic Total Occlusions and Other Occlusions in a High-Volume Catheterization Center.

    PubMed

    Maccia, Carlo; Malchair, Françoise; Gobert, Isabelle; Louvard, Yves; Lefevre, Thierry

    2015-10-15

    The increasing number and complexity of these procedures have led to a higher number of patients at risk for tissue reactions like skin injuries. Monitoring of their dose indicators is essential in recognizing these patients. The aim of this work was to determine local diagnostic reference levels (DRLs) for recanalization of chronic total occlusion (CTO) and other occlusions procedures. All data from patients who underwent cardiac procedures were reviewed and classified according to their complexity. Dose indicators such as fluoroscopy time (FT), dose area product (DAP), and air kerma at patient entrance reference point (AKr) were recorded. Correlations with patient's body mass index, operators, procedure strategy, and complexity were studied. For CTO, the mean DAP, AKr, and FT were 252 ± 234 Gycm(2), 3,985 ± 3,579 mGy, and 47 ± 36 minutes, respectively. To better reflect the non-Gaussian distribution of data, the median and the 75th percentile values were also reported: median DAP, 172 Gycm(2); 75th percentile DAP, 350 Gycm(2); median AKr, 2,714 mGy; and 75th percentile AKr, 5,921 mGy. A tentative new set of values were suggested to take into account the complexity difference in recanalization of total occlusions according to their antegrade or retrograde approach. These approach-specific DRLs for total occlusions were mean DAP (120 ± 114 Gycm(2)), mean AKr (1,789 ± 1,933 mGy), and mean FT (22 ± 18 minutes) for antegrade approach and mean DAP (459 ± 304 Gycm(2)), mean AKr (6,881 ± 4,243 mGy), and mean FT (82 ± 40 minutes) for retrograde approach. The other significant values were median DAP (84 Gycm(2)), 75th percentile DAP (147 Gycm(2)), median AKr (1,160 mGy), and 75th percentile AKr (2,176 mGy) for antegrade approach and median DAP (422 Gycm(2)), 75th percentile DAP (552 Gycm(2)), median AKr (6,295 mGy), and 75th percentile AKr (8,064 mGy) for retrograde approach. In conclusion, a set of local DRL values from a large center were assessed

  16. Indian Education: A National Tragedy--A National Challenge. 1969 Report of the Committee on Labor and Public Welfare, United States Senate, Made by Its Special Subcommittee on Indian Education.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Public Welfare.

    Senate Resolution 165, 90th Congress, authorized an investigation into the education of Indian children. Subsequent resolutions extended the investigation, the results of which are synthesized in this report. Historical discussion of national policy toward the American Indian, the effects of Federal legislation, and the failures of Federal schools…

  17. Experiences of a local arrangement committee for a large scientific conference

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This paper is an an invited condensation of a paper that appeared in Acta. Hort. 745: 513-532 last year. It describes the history and organization of the combined meeting of the 90th Annual Meeting of the Potato Association of America, the VI International Solanaceae Conference, and the III Solanace...

  18. Former ESO DG Adriaan Blaauw Turned 90

    NASA Astrophysics Data System (ADS)

    2004-06-01

    On April 12, former ESO DG professor Adriaan Blaauw reached his 90th birthday. Adriaan, together with many friends, family members, colleagues from The Netherlands and abroad, celebrated this occasion on April 17, during an informal get-together at the 19th-century country-mansion Nienoord in Leek, near Groningen.

  19. 26 CFR 16.3-1 - Returns as to the creation of or transfers to certain foreign trusts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 14 2013-04-01 2013-04-01 false Returns as to the creation of or transfers to... Returns as to the creation of or transfers to certain foreign trusts. (a) Requirement of return. Every... section 6048 and this section shall be filed on or before the 90th day after either the creation of...

  20. 26 CFR 16.3-1 - Returns as to the creation of or transfers to certain foreign trusts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 14 2012-04-01 2012-04-01 false Returns as to the creation of or transfers to... Returns as to the creation of or transfers to certain foreign trusts. (a) Requirement of return. Every... section 6048 and this section shall be filed on or before the 90th day after either the creation of...

  1. 26 CFR 16.3-1 - Returns as to the creation of or transfers to certain foreign trusts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 14 2011-04-01 2010-04-01 true Returns as to the creation of or transfers to... Returns as to the creation of or transfers to certain foreign trusts. (a) Requirement of return. Every... section 6048 and this section shall be filed on or before the 90th day after either the creation of...

  2. Discovery of Unforeseen Lead Level Optimization Issues for High pH and Low DIC Conditions

    EPA Science Inventory

    A large northeast water utility serving over 500,000 retail and wholesale customers had historically been slightly below the 90th percentile Action Level for lead. The system had been operating at a pH of approximately 10.3, a DIC concentration of approximately 5 mg/L as C, and ...

  3. 15. Arched, concrete bridge along elevated rightofway of Shaker Rapid ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Arched, concrete bridge along elevated right-of-way of Shaker Rapid Transit through the east side of city of Cleveland, labelled: 'View Toward West Along Northerly Side Arches at E. 90th St. and Westerly.' 1914. - Shaker Heights Rapid Transit Line, Cleveland, Cuyahoga County, OH

  4. 38 CFR 21.7051 - Extended period of eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... period of eligibility in a course not organized on a term, quarter or semester basis, or (ii) On or before the commencing date of the first ordinary term, quarter or semester following the 90th day after... extended period of eligibility in a course organized on a term, quarter or semester basis. (Authority: 38...

  5. 38 CFR 21.5296 - Extended period of eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... not organized on a term, quarter or semester basis, or (3) Must be on or before the first day of the first ordinary term, quarter or semester following the 90th day after the veteran's application for an... course organized on a term, quarter or semester basis. (Authority: 38 U.S.C. 3232; Pub. L. 99-576)...

  6. WISC-R Verbal and Performance IQ Discrepancy in an Unselected Cohort: Clinical Significance and Longitudinal Stability.

    ERIC Educational Resources Information Center

    Moffitt, Terrie E.; Silva, P. A.

    1987-01-01

    Examined children whose Wechsler Intelligence Scale for Children-Revised (WISC-R) verbal and performance Intelligence Quotient discrepancies placed them beyond the 90th percentile. Longitudinal study showed 23 percent of the discrepant cases to be discrepant at two or more ages. Studied frequency of perinatal difficulties, early childhood…

  7. SOLVING COPPER CORROSION PROBLEMS WHILE MAINTAINING LEAD CONTROL IN A HIGH ALKALINITY WATER USING ORTHOPHOSPHATE

    EPA Science Inventory

    Lead and Copper Rule sampling in 1992 uncovered high copper levels in many homes in the Indian Hill Water Works, Ohio (IHWW) water system. The 90th percentile copper and lead levels were 1.63 mg/L and 0.012 mg/L, respectively. IHWW supplies water to several suburban communities t...

  8. 26 CFR 1.6038A-6 - Failure to furnish information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... therein, are pending. In no event shall any such period expire before the 90th day after the day on which... party and the reporting corporation (including any transaction engaged in by a partnership that is attributed to the reporting corporation under § 1.6038A-1(e)(2)) if a summons is issued to the...

  9. New Challenges for Home Economics Educators

    ERIC Educational Resources Information Center

    Hurt, Mary Lee; Alexander, Margaret

    1969-01-01

    On October 16, 1968, the 90th Congress passed Public Law 90-576 to amend the Vocational Education Act of 1963. The authors of this article, in their positions in the U.S. Office of Education, have been actively involved in planning the implementation of Part F of Title I, entitled "Consumer and Homemaking Education." They present here challenges…

  10. Psychosocial Factors in Adolescent and Young Adult Self-Reported Depressive Symptoms: Causal or Correlational Associations?

    ERIC Educational Resources Information Center

    Steinhausen, Hans-Christoph; Haslimeier, Claudia; Metzke, Christa Winkler

    2007-01-01

    Using a large longitudinal representative community sample, this study identified three groups of subjects who were depressed either in pre-adolescence, late adolescence or early adulthood, and matched by age and gender to controls without depression. The 90th percentile on one or two self-reported symptom scales [i. e. the Center for…

  11. The Incidence of Potentially Gifted Students within a Special Education Population

    ERIC Educational Resources Information Center

    Barnard-Brak, Lucy; Johnsen, Susan K.; Hannig, Alyssa Pond; Wei, Tianlan

    2015-01-01

    From a sample of 13,176 children with disabilities who were a part of the Special Education Elementary Longitudinal Study, 330 students achieved a score at the 90th percentile or higher on the Woodcock-Johnson III. These children represent some 9.1% of children who have disabilities nationally and who might be identified as gifted or academically…

  12. Solanaceae VI – Genomics Meets Biodiversity

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This volume, edited by the five authors above, is based on contributed papers presented at a combined conference of the VI International Solanaceae Conference, the 90th Annual Meeting of the Potato Association of America, and the III Solanaceae Genomics Conference. The meeting was held in Madison Wi...

  13. Does History Matter? Ask the Armenians

    ERIC Educational Resources Information Center

    Totten, Samuel

    2005-01-01

    This article discusses the history of the Armenian genocide and the impact it brought on the Armenians. The author relates his experience attending a two-day memorial commemoration in the desert of Syria for the 90th anniversary of the Armenian genocide that he became fully aware of how profound the memory of that human disaster is for today's…

  14. Spectral analyses of satellite geopotential missions

    NASA Astrophysics Data System (ADS)

    Melvin, Peter J.

    1989-06-01

    A new, geometrical, first order, nonresonant, frozen orbit theory was developed based on Orlov's uniformly rotating plane of constant inclination. Perturbation spectra generated from a 90th order subset of OSU86F are shown for the ill-fated 1984 JHU/APL SAGE proposal for a pair of TRANSIT satellites at 400 km altitude with a 93.5 deg inclination.

  15. 20 CFR 411.171 - When does the period of using a ticket end?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... month in which your ticket is no longer assigned to an EN or State VR agency acting as an EN (see § 411... explanation of the 90-day extension period); or (d) If your ticket was in VR cost reimbursement status as described in § 411.166(j), the 90th day following the date the State VR agency closes your case, unless...

  16. 20 CFR 411.171 - When does the period of using a ticket end?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... month in which your ticket is no longer assigned to an EN or State VR agency acting as an EN (see § 411... explanation of the 90-day extension period); or (d) If your ticket was in VR cost reimbursement status as described in § 411.166(j), the 90th day following the date the State VR agency closes your case, unless...

  17. 20 CFR 411.171 - When does the period of using a ticket end?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... month in which your ticket is no longer assigned to an EN or State VR agency acting as an EN (see § 411... explanation of the 90-day extension period); or (d) If your ticket was in VR cost reimbursement status as described in § 411.166(j), the 90th day following the date the State VR agency closes your case, unless...

  18. Beauty and physics: 13 important contributions of Chen Ning Yang

    NASA Astrophysics Data System (ADS)

    Shi, Yu

    2014-06-01

    In 2012, Chen Ning Yang received a 90th birthday gift in the form of a black cube inscribed with his 13 most important contributions, which cover four major areas of physics: statistical mechanics, condensed matter physics, particle physics and field theory. We briefly describe these 13 contributions and make general comments about Yang's distinctive style as a trailblazing leader in research.

  19. 42 CFR 413.343 - Resident assessment data.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... performance of patient assessments on the 5th, 14th, 30th, 60th, and 90th days of posthospital SNF care and...) Noncompliance with assessment schedule. CMS pays a default rate for the Federal rate when a SNF fails to comply... a patient's care for which the SNF is not in compliance with the assessment schedule....

  20. 42 CFR 413.343 - Resident assessment data.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... performance of patient assessments on the 5th, 14th, 30th, 60th, and 90th days of posthospital SNF care and...) Noncompliance with assessment schedule. CMS pays a default rate for the Federal rate when a SNF fails to comply... a patient's care for which the SNF is not in compliance with the assessment schedule....

  1. 42 CFR 413.343 - Resident assessment data.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... performance of patient assessments on the 5th, 14th, 30th, 60th, and 90th days of posthospital SNF care and...) Noncompliance with assessment schedule. CMS pays a default rate for the Federal rate when a SNF fails to comply... a patient's care for which the SNF is not in compliance with the assessment schedule....

  2. 42 CFR 413.343 - Resident assessment data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... performance of patient assessments on the 5th, 14th, 30th, 60th, and 90th days of posthospital SNF care and...) Noncompliance with assessment schedule. CMS pays a default rate for the Federal rate when a SNF fails to comply... a patient's care for which the SNF is not in compliance with the assessment schedule....

  3. General Federal Support for Higher Education: An Analysis of Five Formulas.

    ERIC Educational Resources Information Center

    Farrell, Robert L.; Andersen, Charles J.

    Five approaches to federal funding of higher education are described. (1) The Miller Bill (H.R. 875, 90th Congress) would provide $150 million in institutional grants for science education to be distributed in three equal parts, based on the number of federal "project awards" (grants-in-aid) an institution receives, enrollments in science courses,…

  4. 78 FR 35115 - Listing of Color Additives Exempt From Certification; Mica-Based Pearlescent Pigments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ... of mica-based pearlescent pigments in food (Sec. 73.350) and ingested drugs (Sec. 73.1350) (71 FR... FR 16784), FDA announced that a color additive petition (CAP 2C0294) had been filed by E. & J. Gallo... and at the 90th percentile, respectively, for the subgroup of children aged 2 to 5 years (71 FR...

  5. 47 CFR 73.609 - Zones.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... standard parallels 291/2° and 451/2°; North American datum): Beginning at the most easterly point on the... Illinois to the 90th meridian; thence north along this meridian to the 43.5° parallel; thence east along this parallel to the United States-Canada border; thence southerly and following that border until...

  6. 47 CFR 73.609 - Zones.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... standard parallels 291/2° and 451/2°; North American datum): Beginning at the most easterly point on the... Illinois to the 90th meridian; thence north along this meridian to the 43.5° parallel; thence east along this parallel to the United States-Canada border; thence southerly and following that border until...

  7. 47 CFR 73.609 - Zones.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... standard parallels 291/2° and 451/2°; North American datum): Beginning at the most easterly point on the... Illinois to the 90th meridian; thence north along this meridian to the 43.5° parallel; thence east along this parallel to the United States-Canada border; thence southerly and following that border until...

  8. Equity and Efficiency of Community College Appropriations: The Role of Local Financing

    ERIC Educational Resources Information Center

    Dowd, Alicia C.; Grant, John L.

    2006-01-01

    This study analyzes the equity of community college financing and demonstrates intrastate variations in appropriations to community colleges. The ratio of 90th to 10th percentile values ranges from 2.0 to 2.8 in half of the states analyzed, levels which are considered high in comparison to K-12 finance inequities. In 10 states with high revenue…

  9. A Summary of Selected Legislation Relating to the Handicapped, 1968.

    ERIC Educational Resources Information Center

    Department of Health, Education, and Welfare, Washington, DC.

    Legislation affecting the handicapped enacted during the Second Session of the 90th Congress (1968) is presented along with tabular data on the legislative history of each law. Laws relating to education are the Vocational Education Amendments, Higher Education Amendments, Early Education Assistance, and To Increase the Size of the Board of…

  10. The Relationship between Self-Concept, Ability, and Academic Programming among Twice-Exceptional Youth

    ERIC Educational Resources Information Center

    Foley-Nicpon, Megan; Assouline, Susan G.; Fosenburg, Staci

    2015-01-01

    Researchers investigated the self-concept profiles of twice-exceptional students in relationship to their cognitive ability and participation in educational services. All subjects (N = 64) had high ability (IQ score at or above the 90th percentile) and were diagnosed with either an autism spectrum disorder (ASD; n = 53) or specific learning…

  11. 26 CFR 16.3-1 - Returns as to the creation of or transfers to certain foreign trusts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 14 2014-04-01 2013-04-01 true Returns as to the creation of or transfers to... Returns as to the creation of or transfers to certain foreign trusts. (a) Requirement of return. Every... section 6048 and this section shall be filed on or before the 90th day after either the creation of...

  12. 26 CFR 16.3-1 - Returns as to the creation of or transfers to certain foreign trusts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Returns as to the creation of or transfers to... Returns as to the creation of or transfers to certain foreign trusts. (a) Requirement of return. Every... section 6048 and this section shall be filed on or before the 90th day after either the creation of...

  13. IGF-I levels and depressive disorders: results from the Study of Health in Pomerania (SHIP).

    PubMed

    Sievers, C; Auer, M K; Klotsche, J; Athanasoulia, A P; Schneider, H J; Nauck, M; Völzke, H; John, U; Schulz, A; Freyberger, H J; Friedrich, N; Biffar, R; Stalla, G K; Wallaschofski, H; Grabe, H J

    2014-06-01

    In vitro and in vivo models revealed that the somatotropic system exerts central effects on the central nervous system. Disturbances to this system such as in the case of growth hormone deficiency or growth hormone excess, are associated with a wide range of psychiatric disorders. Nonetheless, there is no epidemiological data available regarding the influence of growth hormone and its mediator, insulin-like growth factor I (IGF-I), on depressive disorders. The objective of this study was to investigate whether endogenous IGF-I levels may predict depression in humans. We included 4079 adult subjects from the Study of Health in Pomerania (SHIP), a population-based study with a 5-year follow-up period. The main predictor was the baseline IGF-I value categorized in three levels as <10th percentile, between the 10th and the 90th percentile (the reference group) and >90th percentile. The outcome measure was the incidence of depressive disorders according to the Composite International Diagnostic-Screener (CID-S). After adjustment for potential confounding variables, females with IGF-I levels below the 10th percentile had a higher incidence of depressive disorders during follow-up (OR 2.70 95% CI 1.38-5.28, p=0.004) compared to females within the reference group (10th-90th percentile). Among males, those with IGF-I levels above the 90th percentile had a higher risk of depressive disorder (OR 3.26 95% CI 1.52-6.98, p=0.002) than those within the 10th-90th percentile. In conclusion we can demonstrate that low IGF-I levels in females and high IGF-I levels in males predict the development of depressive disorders in this general adult population sample. PMID:24507017

  14. Right and Left Ventricular Myocardial Perfusion Reserves Correlate with Right Ventricular Function and Pulmonary Hemodynamics in Patients with Pulmonary Arterial Hypertension1

    PubMed Central

    Skrok, Jan; Shehata, Monda L.; Singh, Sukhminder; Sibley, Christopher T.; Boyce, Danielle M.; Lechtzin, Noah; Girgis, Reda E.; Mathai, Steven C.; Goldstein, Thomas A.; Zheng, Jie; Lima, João A. C.; Bluemke, David A.; Hassoun, Paul M.

    2011-01-01

    Purpose: To evaluate the relationships of right ventricular (RV) and left ventricular (LV) myocardial perfusion reserves with ventricular function and pulmonary hemodynamics in patients with pulmonary arterial hypertension (PAH) by using adenosine stress perfusion cardiac magnetic resonance (MR) imaging. Materials and Methods: This HIPAA-compliant study was institutional review board approved. Twenty-five patients known or suspected to have PAH underwent right heart catheterization and adenosine stress MR imaging on the same day. Sixteen matched healthy control subjects underwent cardiac MR imaging only. RV and LV perfusion values at rest and at adenosine-induced stress were calculated by using the Fermi function model. The MR imaging–derived RV and LV functional data were calculated by using dedicated software. Statistical testing included Kruskal-Wallis tests for continuous data, Spearman rank correlation tests, and multiple linear regression analyses. Results: Seventeen of the 25 patients had PAH: 11 with scleroderma-associated PAH, and six with idiopathic PAH. The remaining eight patients had scleroderma without PAH. The myocardial perfusion reserve indexes (MPRIs) in the PAH group (median RV MPRI, 1.7 [25th–75th percentile range, 1.3–2.0]; median LV MPRI, 1.8 [25th–75th percentile range, 1.6–2.1]) were significantly lower than those in the scleroderma non-PAH (median RV MPRI, 2.5 [25th–75th percentile range, 1.8–3.9] [P = .03]; median LV MPRI, 4.1 [25th–75th percentile range, 2.6–4.8] [P = .0003]) and control (median RV MPRI, 2.9 [25th–75th percentile range, 2.6–3.6] [P < .01]; median LV MPRI, 3.6 [25th–75th percentile range, 2.7–4.1] [P < .01]) groups. There were significant correlations between biventricular MPRI and both mean pulmonary arterial pressure (mPAP) (RV MPRI: ρ = −0.59, Bonferroni P = .036; LV MPRI: ρ = −0.79, Bonferroni P < .002) and RV stroke work index (RV MPRI: ρ = −0.63, Bonferroni P = .01; LV MPRI: ρ =

  15. Monitoring the Migrations of Wild Snake River Spring/Summer Chinook Salmon Juveniles, 2007-2008 Report of Research.

    SciTech Connect

    Achord, Stephen; Sandford, Benjamin P.; Hockersmith, Eric E.

    2009-05-26

    2007-2008 showed these antennas (and anchoring method) are not adequate to withstand high spring flows in this drainage. Future plans involve removing these antennas before high spring flows. (5) At Little Goose Dam in 2008, length and/or weight were taken on 505 recaptured fish from 12 Idaho stream populations. Fish had grown an average of 40.1 mm in length and 10.6 g in weight over an average of 288 d. Their mean condition factor declined from 1.25 at release (parr) to 1.05 at recapture (smolt). (6) Mean release lengths for detected fish were significantly larger than for fish not detected the following spring and summer (P < 0.0001). (7) Fish that migrated through Lower Granite Dam in April and May were significantly larger at release than fish that migrated after May (P < 0.0001) (only 12 fish migrated after May). (8) In 2008, peak detections at Lower Granite Dam of parr tagged during summer 2007 (from the 12 stream populations in Idaho and 4 streams in Oregon) occurred during moderate flows of 87.5 kcfs on 7 May and high flows of 197.3 kcfs on 20 May. The 10th, 50th, and 90th percentile passage occurred on 30 April, 11 May, and 23 May, respectively. (9) In 2007-2008, estimated parr-to-smolt survival to Lower Granite Dam for Idaho and Oregon streams (combined) averaged 19.4% (range 6.2-38.4% depending on stream of origin). In Idaho streams the estimated parr-to-smolt survival averaged 21.0%. This survival was the second highest since 1993 for Idaho streams. Relative parr densities were lower in 2007 (2.4 parr/100 m{sup 2}) than in all previous years since 2000. In 2008, we observed low-to-moderate flows prior to mid-May and relatively cold weather conditions throughout the spring migration season. These conditions moved half of the fish through Lower Granite Dam prior to mid-May; then high flows moved 50 to 90% of the fish through the dam in only 12 days. Clearly, complex interrelationships of several factors drive the annual migrational timing of the stocks.

  16. Monitoring the Migrations of Wild Snake River Spring/Summer Chinook Salmon Juveniles, 2007-2008

    SciTech Connect

    Achord, Stephen; Sandford, Benjamin P.; Hockersmith, Eric E.

    2009-07-09

    -2008 showed these antennas (and anchoring method) are not adequate to withstand high spring flows in this drainage. Future plans involve removing these antennas before high spring flows. (5) At Little Goose Dam in 2008, length and/or weight were taken on 505 recaptured fish from 12 Idaho stream populations. Fish had grown an average of 40.1 mm in length and 10.6 g in weight over an average of 288 d. Their mean condition factor declined from 1.25 at release (parr) to 1.05 at recapture (smolt). (6) Mean release lengths for detected fish were significantly larger than for fish not detected the following spring and summer (P < 0.0001). (7) Fish that migrated through Lower Granite Dam in April and May were significantly larger at release than fish that migrated after May (P < 0.0001) (only 12 fish migrated after May). (8) In 2008, peak detections at Lower Granite Dam of parr tagged during summer 2007 (from the 12 stream populations in Idaho and 4 streams in Oregon) occurred during moderate flows of 87.5 kcfs on 7 May and high flows of 197.3 kcfs on 20 May. The 10th, 50th, and 90th percentile passage occurred on 30 April, 11 May, and 23 May, respectively. (9) In 2007-2008, estimated parr-to-smolt survival to Lower Granite Dam for Idaho and Oregon streams (combined) averaged 19.4% (range 6.2-38.4% depending on stream of origin). In Idaho streams the estimated parr-to-smolt survival averaged 21.0%. This survival was the second highest since 1993 for Idaho streams. Relative parr densities were lower in 2007 (2.4 parr/100 m2) than in all previous years since 2000. In 2008, we observed low-to-moderate flows prior to mid-May and relatively cold weather conditions throughout the spring migration season. These conditions moved half of the fish through Lower Granite Dam prior to mid-May; then high flows moved 50 to 90% of the fish through the dam in only 12 days. Clearly, complex interrelationships of several factors drive the annual migrational timing of the stocks.

  17. Inter- and Intrafraction Variability in Liver Position in Non-Breath-Hold Stereotactic Body Radiotherapy

    SciTech Connect

    Case, Robert B.; Sonke, Jan-Jakob; Moseley, Douglas J.; Kim, John; Brock, Kristy K.; Dawson, Laura A.

    2009-09-01

    Purpose: The inter- and intrafraction variability of liver position was assessed in patients with liver cancer treated with kilovoltage cone-beam computed tomography (CBCT)-guided stereotactic body radiotherapy. Methods and Materials: A total of 314 CBCT scans obtained in the treatment position immediately before and after each fraction were evaluated from 29 patients undergoing six-fraction, non-breath-hold stereotactic body radiotherapy for unresectable liver cancer. Off-line, the CBCT scans were sorted into 10 bins, according to the phase of respiration. The liver position (relative to the vertebral bodies) was measured using rigid alignment of the exhale CBCT liver with the exhale planning CT liver, following the alignment of the vertebrae. The interfraction liver position change was measured by comparing the pretreatment CBCT scans, and the intrafraction change was measured from the CBCT scans obtained immediately before and after each fraction. Results: The mean amplitude of liver motion for all patients was 1.8 mm (range, 0.1-5.7), 8.0 mm (range, 0.1-18.8), and 4.3 mm (range 0.1-12.1) in the medial-lateral (ML), craniocaudal (CC), and anteroposterior (AP) directions, respectively. The mean absolute ML, CC, and AP interfraction changes in liver position were 2.0 mm (90th percentile, 4.2), 3.5 mm (90th percentile, 7.3), and 2.3 mm (90th percentile, 4.7). The mean absolute intrafraction ML, CC, and AP changes were 1.3 mm (90th percentile, 2.9), 1.6 mm (90th percentile, 3.6), and 1.5 mm (90th percentile, 3.1), respectively. The interfraction changes were significantly larger than the intrafraction changes, with a CC systematic error of 2.9 and 1.1 mm, respectively. The intraobserver reproducibility ({sigma}, n = 29 fractions) was 1.3 mm in the ML, 1.4 mm in the CC, and 1.6 mm in the AP direction. Conclusion: Interfraction liver position changes relative to the vertebral bodies are an important source of geometric uncertainty, providing a rationale for

  18. Shark scales

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Close examination of the skin of a fast-swimming shark appears to confirm Langley's aerodynamically efficient Riblet concept. This view magnified 30 times, reveals that projections on the shark skin -dermal denticles- line up to form grooves similar to those that have reduced drag in wind tunnels. L83-9167: Mother Nature's riblet, this shark's dermal denticle has been magnified 3,000 times. Photograph published in Winds of Change, 75th Anniversary NASA publication (page 123), by James Schultz.

  19. Quality Improvement Project to Improve Patient Satisfaction With Pain Management: Using Human-Centered Design.

    PubMed

    Trail-Mahan, Tracy; Heisler, Scott; Katica, Mary

    2016-01-01

    In this quality improvement project, our health system developed a comprehensive, patient-centered approach to improving inpatient pain management and assessed its impact on patient satisfaction across 21 medical centers. Using human-centered design principles, a bundle of 6 individual and team nursing practices was developed. Patient satisfaction with pain management, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems pain composite score, increased from the 25th to just under the 75th national percentile. PMID:26447343

  20. q-bosons, Toda lattice, Pieri rules and Baxter q-operator

    NASA Astrophysics Data System (ADS)

    Duval, Antoine; Pasquier, Vincent

    2016-04-01

    We use the Pieri rules to recover the q-boson model and show it is equivalent to a discretized version of the relativistic Toda chain. We identify its semi infinite transfer matrix and the corresponding Baxter Q-matrix with half vertex operators related by an ω-duality transformation. We observe that the scalar product of two higher spin XXZ wave functions can be expressed with a Gaudin determinant. In honour of Rodney Baxter’s 75th birthday.