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Sample records for 63-year-old man underwent

  1. Lemierre's syndrome due to Klebsiella pneumoniae in a 63-year-old man with diabetes: a case report

    PubMed Central

    2012-01-01

    Introduction Lemierre's syndrome was originally documented to be caused by Fusobacterium necrophorum. It is a very rare condition with a prevalence of one to 14.4 instances per million. Its presentation is varied, not only in composition but also in the infecting organism. Treatment with anticoagulants has been controversial and applied only on a case-by-case basis. Case presentation A 63-year-old Saudi man who had had uncontrolled diabetes mellitus for 47 years presented to our facility with a five-day history of swelling on the right side of his neck and fever. The swelling progressively increased in size and was associated with pain, dysphagia, odynophagia, change of voice ('hot potato voice'), and reduced appetite. Abscess content culture and sensitivity testing revealed Klebsiella pneumoniae. However, blood culture results were repeatedly negative. The abscess was incised and drained without any complication. Our patient was treated with clindamycin and cefuroxime. Warfarin was also administered concurrently for six weeks, for an isolated internal jugular vein thrombosis (IJV), with complete resolution of the thrombus. Normoglycemia was achieved and our patient was discharged after complete wound healing and the return of his biochemical parameters to normal. Conclusions Only two cases of Lemierre's syndrome in patients with diabetes due to K. pneumoniae have been reported previously. A review of the literature suggested that an association exists between deep neck infections due to K. pneumoniae and diabetes mellitus. The reasons for this association are still not clear. This poses a question as to whether diabetes mellitus specifically predisposes these patients to infection with this organism. It is suggested that clinicians should consider infectious agents other than F. necrophorum in the causation of Lemierre's syndrome, especially in patients with diabetes. PMID:22472458

  2. [Longevity in tetralogy of Fallot. The natural history of a 63-year-old man living without surgery].

    PubMed

    Pentimone, F; Mechelli, S; Riccioni, S; Del Corso, L

    1992-01-01

    We report the natural history, the clinical, radiological, echocardiographic and hemodynamic pattern of a living sixty-three year old man with tetralogy of Fallot and cyanosis since birth. We discuss the possible circulatory adaptations which allowed exceptional survival up to the seventh decade: it is the sixth case reported in the literature. PMID:1470392

  3. [Acute kidney failure and renal replacement therapy after colonoscopy in a 63-year-old woman].

    PubMed

    Bös, D

    2015-11-01

    A 63-year-old woman presented with intestinal disorder, alternating between obstipation and diarrhoea. Sodium phosphate/diphosphate (Fleet®) was used in preparation for colonoscopy. Within 24 h the patient developed severe hyperphosphatemia and oliguric acute kidney failure with the need of renal replacement therapy. This case illustrates the rare event of phosphate nephropathy after colonoscopy. PMID:26482077

  4. Fibrohistiocytoma combined with an aneurysmal bone cyst at T7 in a 63-year-old woman

    PubMed Central

    LI, QI; FU, YISHAN; DONG, YANG; ZENG, BINGFANG; ZHANG, CHANGQING

    2013-01-01

    We present a case of spinal tumor, with fibrohistiocytoma combined with aneurysmal bone cyst (ABC) at the pedicle and transverse process of T7 in a 63-year-old female. ABC is a rare skeletal tumor and spinal ABC is extremely rare. Fibrohistiocytoma is a type of primary benign bone tumor. ABC is also a rare bone tumor that most often occurs in the pelvis. The combined lesion of two primary bone benign tumors is relatively rare in clinic. In addition, fibrohistiocytoma and ABC are widely confused with other giant cell containing tumors of the bone. X-rays, magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) scans were performed and assessed. Finally, the diagnosis was confirmed by pathological tests. The patient underwent surgery and had an extremely good recovery. The correct diagnosis of a spine tumor is important when determining the surgical procedure. PMID:24223633

  5. Porocarcinoma coexisting at a site of Bowen disease in a 63-year-old woman.

    PubMed

    Zheng, L-Q; Han, X-C; Huang, Y; Li, H-W; Niu, X-D; Li, J

    2015-04-01

    Porocarcinoma is an unusual, locally aggressive and potentially fatal neoplasm. Several cutaneous malignancies have been described in association with porocarcinoma, including squamous cell carcinoma, basal cell carcinoma and tricholemmal carcinoma. Previous reports have indicated that the occurrence of malignant tumours in combination with porocarcinoma is extremely rare, in particular with regard to Bowen disease (BD). We report an uncommon case of porocarcinoma occurring synchronously in a single BD lesion in a 63-year-old woman with multiple BD lesions. The clinical and histological findings confirmed this diagnosis. PMID:25559897

  6. Idiopathic Bilateral Adrenal Hemorrhage in a 63-Year-Old Male: A Case Report and Review of the Literature

    PubMed Central

    Bodukam, Vijay Kumar; Thakur, Kshitij; Singh, Amandeep; Jenkins, Donald; Bahl, Jaya

    2015-01-01

    Adrenal hemorrhage is a largely uncommon condition typically caused by a number of factors including infection, MI, CHF, anticoagulants, trauma, surgery, and antiphospholipid syndrome. Yet, idiopathic bilateral hemorrhage is rare. The authors present a case of a 63-year-old male who presented with abdominal pain that was eventually diagnosed as bilateral adrenal hemorrhages due to an unknown origin. Abdominal CT revealed normal adrenal glands without enlargement, but an MRI displayed enlargement due to hemorrhage in both adrenals. There was no known cause; the patient had not suffered from an acute infection and was not on anticoagulants, and the patient's history did not reveal any of the other known causative factors. The case underscores the importance of keeping bilateral adrenal hemorrhages on the list of differentials even when a cause is not immediately clear. It also raises the question of whether CT is the most sensitive test in the diagnosis of adrenal hemorrhage and whether the diagnostic approach should place greater weight on MRI. The case highlights the need for prompt therapy with steroids once bilateral hemorrhage is suspected to avert the development or progression of adrenal insufficiency. PMID:25973281

  7. Expanding the phenotype in aminoacylase 1 (ACY1) deficiency: characterization of the molecular defect in a 63-year-old woman with generalized dystonia.

    PubMed

    Sass, Jörn Oliver; Vaithilingam, Jathana; Gemperle-Britschgi, Corinne; Delnooz, Cathérine C S; Kluijtmans, Leo A J; van de Warrenburg, Bart P C; Wevers, Ron A

    2016-06-01

    Aminoacylase 1 (ACY1) deficiency is an organic aciduria due to mutations in the ACY1 gene. It is considered much underdiagnosed. Most individuals known to be affected by ACY1 deficiency have presented with neurologic symptoms. We report here a cognitively normal 63-year-old woman who around the age of 12 years had developed dystonic symptoms that gradually evolved into generalized dystonia. Extensive investigations, including metabolic diagnostics and diagnostic exome sequencing, were performed to elucidate the cause of dystonia. Findings were only compatible with a diagnosis of ACY1 deficiency: the urinary metabolite pattern with N-acetylated amino acids was characteristic, there was decreased ACY1 activity in immortalized lymphocytes, and two compound heterozygous ACY1 mutations were detected, one well-characterized c.1057C>T (p.Arg353Cys) and the other novel c.325A>G (p.Arg109Gly). Expression analysis in HEK293 cells revealed high residual activity of the enzyme with the latter mutation. However, following co-transfection of cells with stable expression of the c.1057C>T variant with either wild-type ACY1 or the c.325A>G mutant, only the wild-type enhanced ACY1 activity and ACY1 presence in the Western blot, suggesting an inhibiting interference between the two variants. Our report extends the clinical spectrum of ACY1 deficiency to include dystonia and indicates that screening for organic acidurias deserves consideration in patients with unexplained generalized dystonia. PMID:26686503

  8. [A man with sexual disinhibition caused by paraneoplastic limbic encephalitis].

    PubMed

    de Vries, C L; Koers, H

    2013-01-01

    A 63-year-old man with symptoms of depression and sexual disinhibition was admitted to a psychiatric clinic for the elderly. Because the man’s symptoms rapidly became more severe he was referred to the emergency room. There, his illness was diagnosed as paraneoplastic limbic encephalitis with positive anti-Hu antibodies; this is a paraneoplastic neurological syndrome presenting with short-term memory loss, epileptic seizures and psychiatric symptoms. For the prognosis of the illness it is essential that the syndrome is diagnosed as early as possible. Since patients sometimes present with mainly psychiatric symptoms it is important that psychiatrists are fully informed about the symptoms and are able to make an accurate diagnosis. PMID:23408365

  9. Underwing Compression Vortex-Attenuation Device

    NASA Technical Reports Server (NTRS)

    Patterson, James C., Jr.

    1994-01-01

    Underwing compression vortex-attenuation device designed to provide method for attenuating lift-induced vortex generated by wings of airplane. Includes compression panel attached to lower surface of wing, facing perpendicular to streamwise airflow. Concept effective on all types of aircraft. Causes increase in wing lift rather than reduction when deployed. Device of interest to aircraft designers and enhances air safety in general.

  10. Rocket man

    NASA Astrophysics Data System (ADS)

    Becklake, John

    2008-06-01

    In the 1950s and 1960s, Wernher von Braun was famous as the man who led the West's journey into space. Some also remember him as the German engineer who developed the V-2 missile that bombarded Antwerp and London at the end of the Second World War. However, many still celebrate Von Braun, who died in 1977, as the man who put the astronauts on the Moon. While this is not strictly true, there is no doubt that Von Braun was one of the most influential engineers, lobbyists and personalities in the Moon-landing project.

  11. Remeasuring man.

    PubMed

    Weisberg, Michael

    2014-05-01

    Samuel George Morton (1799-1851) was the most highly regarded American scientist of the early and middle 19th century. Thanks largely to Stephen Jay Gould's book The Mismeasure of Man, Morton's cranial capacity measurements of different races is now held up as a prime example of and cautionary tale against scientific racism. A team of anthropologists recently reevaluated Morton's work and argued that it was Gould, not Morton, who was biased in his analysis. This article is a reexamination of the Morton and Gould controversy. It argues that most of Gould's arguments against Morton are sound. Although Gould made some errors and overstated his case in a number of places, he provided prima facia evidence, as yet unrefuted, that Morton did indeed mismeasure his skulls in ways that conformed to 19th century racial biases. Gould's critique of Morton ought to remain as an illustration of implicit bias in science. PMID:24761929

  12. Fatal pneumopericardium caused by SF6 gas infusion into the pleural space after pneumonectomy and pericardial resection.

    PubMed

    Shirakusa, T

    1989-06-01

    A 63-year-old man with lung carcinoma underwent a right pneumonectomy and combined resection of the pericardium. Postoperatively, SF6 gas was introduced into the empty pleural space for the protection of excessive shift of heart and mediastinum, but a fatal pneumopericardium occurred. A rare but possible complication of cardiac tamponade after inert gas infusion in patients undergoing combined resection of pericardium is reported. PMID:2721276

  13. [A mixed germ cell tumor that underwent dramatic size changes].

    PubMed

    Kuwayama, Kazuyuki; Takai, Hiroki; Nishiyama, Akira; Hirai, Satoshi; Yokosuka, Kimihiko; Toi, Hiroyuki; Hirano, Kazuhiro; Matsubara, Shunji; Uno, Masaaki; Nishimura, Hirotake

    2014-09-01

    This report describes a mixed germ cell tumor that underwent dramatic size changes. A 12-year-old boy presented to our hospital with a headache that had persisted for two months. Initial magnetic resonance imaging (MRI) revealed a pineal tumor and hydrocephalus. The patient required external ventricular drainage and underwent two endoscopic biopsies. His evaluation involved a total of nine computed tomography (CT) scans prior to the second biopsy;the tumor size had decreased before the second endoscopic biopsy. The tumor consisted of both a germinoma and a teratoma component. The patient was treated with three courses of carboplatin-etoposide (CBDCA-VP) chemotherapy and whole-ventricle radiotherapy (32.1 Gy). However, during the adjuvant therapy, the tumor size increased, necessitating total tumor resection. We speculate that the tumor's initial size reduction was caused by leakage of the cyst component and exposure to the brain CT irradiation. The tumor's subsequent increase in size was due to the recollection of the cystic components and intracranial growing teratoma syndrome (iGTS). Therefore, frequent brain CTs and angiography should be avoided before definitive pathological diagnosis is achieved. Further, the tumor size should be considered, with surgical resection being performed at the optimal time. PMID:25179200

  14. Analysis and Evaluation of Supersonic Underwing Heat Addition

    NASA Technical Reports Server (NTRS)

    Luidens, Roger W.; Flaherty, Richard J.

    1959-01-01

    The linearized theory for heat addition under a wing has been developed to optimize wing geometry, heat addition, and angle of attack. The optimum wing has all of the thickness on the underside of the airfoil, with maximum-thickness point well downstream, has a moderate thickness ratio, and operates at an optimum angle of attack. The heat addition is confined between the fore Mach waves from under the trailing surface of the wing. By linearized theory, a wing at optimum angle of attack may have a range efficiency about twice that of a wing at zero angle of attack. More rigorous calculations using the method of characteristics for particular flow models were made for heating under a flat-plate wing and for several wings with thickness, both with heat additions concentrated near the wing. The more rigorous calculations yield in practical cases efficiencies about half those estimated by linear theory. An analysis indicates that distributing the heat addition between the fore waves from the undertrailing portion of the wing is a way of improving the performance, and further calculations appear desirable. A comparison of the conventional ramjet-plus wing with underwing heat addition when the heat addition is concentrated near the wing shows the ramjet to be superior on a range basis up to Mach number of about B. The heat distribution under the wing and the assumed ramjet and airframe performance may have a marked effect on this conclusion. Underwing heat addition can be useful in providing high-altitude maneuver capability at high flight Mach numbers for an airplane powered by conventional ramjets during cruise.

  15. Coronary risk factors in patients underwent coronary artery bypass grafting.

    PubMed

    Safaei, Nasser; Alikhah, Hossein; Abadan, Younes

    2011-01-01

    Coronary Artery Disease (CAD) risk increases with increasing number of risk factors. This study was aimed to assess different coronary risk factors among Coronary Artery Bypass Grafting (CABG) surgery patients. A total of 700 patients younger than 45 or older than 65 years and underwent CABG in Tabriz Shahid Madani Heart Center since 2003 to 2007 were enrolled. We examined the probable differences of CAD risk factors between male and female groups and age groups. We also assessed the change of risk factors presentation in last 5 years. There was not significant difference between risk factor numbers in <45 and >65 years groups, but smoking and dyslipidemia was more prevalent in patients < 45 than > 65 years old. Hypertension and diabetes mellitus was more prevalent in patients > 65 old than < 45 years old; also differences were found between males and females patients, so that dyslipidemia, diabetes and hypertension were more prevalent in women than men. Some risk factors were recognized as acting more on one gender than the other. Also, the majority of patients have one or more risk factors, but different age and gender groups may have different risk factors that suggest the need for exact programming for appropriate prophylactic and therapeutic interventions in all groups. PMID:21913494

  16. Periodontal status of patient’s underwent hemodialysis therapy

    PubMed Central

    Jenabian, Niloofar; Ghazi Mirsaeed, Ali Mohammad; Ehsani, Hodis; Kiakojori, Amir

    2013-01-01

    Background: Chronic renal failure patients undergoing hemodialysis are susceptible to periodontal diseases due to systemic complications of the disease and using different drugs. The present study investigated the periodontal status of patient’s who underwent hemodialysis, in Babol, northern Iran. Methods: One-hundred-fifteen hemodialysis patients (63 males, 52 females) with the mean age of 47.9±15.3 years were studied at Shahid Beheshti Hospital in Babol, Iran. Periodontal parameters including plaque index (PI), gingival index (GI), clinical attachment level (CAL) and probing pocket depth (PPD) were measured in these patients. The data were collected and analyzed. Results: The PI, GI, CAL and PPD were 2.37±0.55, 2.36±0.63, 3.98±1.61 and 4.41±1.4, respectively. Significant positive correlations were found between the participants’ age and PI (p<0.024) and p<0.001, respectively. Also, CAL was significantly higher in males than females (4.39±1.57 vs. 3.53±1.56, p<0.02). Conclusion: The results show that longer duration of hemodialysis is associated with severe periodontal diseases, especially in males. PMID:24009955

  17. Anomalous Left Anterior Descending Coronary Artery Arising from Pulmonary Artery in a 63 Year-old Male Patient: Case Report and Literature Review

    PubMed Central

    Ismail, Montasser Y.; Nassar, Mohammed I.; Hamad, Mohammed A.

    2015-01-01

    To present a case of a rare congenital coronary anomaly in an adult patient, which was not reported before in Palestine, review the literature, and compare with previously reported cases. PMID:27326352

  18. FDG PET in Intracranial Carcinomatous Meningitis.

    PubMed

    Heimburger, Céline; Bund, Caroline; Namer, Izzie Jacques

    2016-01-01

    A 63-year-old white man, diagnosed with pT3N2 squamous cell lung carcinoma, underwent right upper lobectomy with adjuvant radiochemotherapy. After a partial epileptic seizure, MRI revealed a solitary right frontal metastasis that was treated with surgical resection followed by stereotaxic radiotherapy. Three months later, the patient presented weight loss, weakness, and headache. He underwent a whole-body FDG PET/CT for restaging. It showed intense FDG uptakes on the brain periphery corresponding to nodular meningeal contrast enhancement on MRI leading to the diagnosis of carcinomatous meningitis, despite negative cerebrospinal fluid cytology. PMID:26447391

  19. Man Made Environments

    ERIC Educational Resources Information Center

    Dubos, Rene

    1971-01-01

    In a speech presented before the American Association of School Administrators, Atlantic City, 1971, the author discusses fundamental needs of man and contends that the danger to man is not so much in the destruction of life as in the spoiling of its quality; quality can be gained through diversity. (BY)

  20. Microorganisms and Man.

    ERIC Educational Resources Information Center

    Noble, W. C.

    1983-01-01

    Provides information to update Institute of Biology's Studies in Biology No. 111, "Microorganisms and Man," by W. C. Noble and Jay Naidoo (Edward Arnold, 1979). Topics include: (1) food poisoning; (2) airborn infections in man; (3) infection in animals and plants; and (4) biodegradation and biosynthesis. (JN)

  1. The Green Man

    ERIC Educational Resources Information Center

    Watson-Newlin, Karen

    2010-01-01

    The Jolly Green Giant. Robin Hood. The Bamberg Cathedral. Tales of King Arthur. Ecology. What do they have in common? What legends and ancient myths are shrouded in the tales of the Green Man? Most often perceived as an ancient Celtic symbol as the god of spring and summer, the Green Man disappears and returns year after year, century after…

  2. Manned systems technology discipline

    NASA Technical Reports Server (NTRS)

    Bretoi, Remus

    1990-01-01

    Viewgraphs on manned systems technology discipline for Space Station Freedom are presented. Topics covered include: crew-systems interfaces and interactions; crew training; on-board systems maintenance and support; habitability and environment; and computational human factors.

  3. Man-systems integration and the man-machine interface

    NASA Technical Reports Server (NTRS)

    Hale, Joseph P.

    1990-01-01

    Viewgraphs on man-systems integration and the man-machine interface are presented. Man-systems integration applies the systems' approach to the integration of the user and the machine to form an effective, symbiotic Man-Machine System (MMS). A MMS is a combination of one or more human beings and one or more physical components that are integrated through the common purpose of achieving some objective. The human operator interacts with the system through the Man-Machine Interface (MMI).

  4. Symbolism in prehistoric man.

    PubMed

    Facchini, F

    2000-12-01

    The aptitude for symbolization, characteristic of man, is revealed not only in artistic representations and funerary practices. It is exhibited by every manifestation of human activity or representation of natural phenomena that assumes or refers to a meaning. We can recognize functional symbolism (tool-making, habitative or food technology), social symbolism, (language and social communication) and spiritual symbolism (funerary practices and artistic expressions). On the basis of these concepts, research into symbolism in prehistoric man allows us to recognize forms of symbolism already in the manifestations of the most ancient humans, starting with Homo habilis (or rudolfensis). Toolmaking, social organization and organization of the territory are oriented toward survival and the life of the family group. They attest to symbolic behaviors and constitute symbolic systems by means of which man expresses himself, lives and transmits his symbolic world. The diverse forms of symbolism are discussed with reference to the different phases of prehistoric humanity. PMID:11216422

  5. Recurrence 11 years after complete response to gemcitabine, 5-Fluorouracil, and Cisplatin chemotherapy followed by radiotherapy in a patient with advanced pancreatic cancer: a case report.

    PubMed

    Uchihara, Tomoyuki; Yamashita, Yo-Ichi; Hualin, Wang; Takeishi, Kazuki; Itoh, Shinji; Harimoto, Norihumi; Yoshizumi, Tomoharu; Aishima, Shinichi; Shirabe, Ken; Baba, Hideo; Maehara, Yoshihiko

    2015-05-01

    A 63-year-old man diagnosed with locally advanced pancreatic ductal adenocarcinoma (PDAC; stage IIa) was treated with chemotherapy (gemcitabine, 5-fluorouracil and cisplatin) followed by radiotherapy. He had complete response by imaging and relapse-free survival for 11 years. However, he subsequently presented with local tumor recurrence and underwent pancreaticoduodenectomy followed by chemotherapy; a partial response was achieved. As in liver metastasis of colonic cancer, complete response by imaging in PDAC may not mean pathological complete response. We would propose the importance of adjuvant surgery for a patient with PDAC with complete response by imaging after chemoradiotherapy. PMID:25964569

  6. Eskimo Medicine Man.

    ERIC Educational Resources Information Center

    George, Otto

    "Eskimo Medicine Man" is a record of primitive Alaskan life in the 1930's. It records the experiences in Alaska's remote areas of Dr. Otto George, the last "traveling physician" for the Department of Interior's Indian Service, when in all the territory (an area one-fifth that of the contiguous United States) there were fewer than sixty thousand…

  7. Man as a Species.

    ERIC Educational Resources Information Center

    Solem, Alan; And Others

    Written in 1964, the document represents experimental material of the Anthropology Curriculum Study Project. The objectives of the project were to discuss the evolution of man as distinguished from the evolution of other species and as related to culture, and to emphasize human diversity. Three brief essays are presented. The first, "The Species…

  8. Ethology and Man

    ERIC Educational Resources Information Center

    Biology and Human Affairs, 1971

    1971-01-01

    Reviews four texts and compilations of papers in an effort to assess the relevance of animal behavior studies to anthropology and sociology. Concludes that where a basic element of behavior occurs widely throughout the animal kingdom, especially in the higher mammals and primates, we may expect to find a manifestation in man." Limitations of the…

  9. [Maggots and man].

    PubMed

    Mawas, Edouard

    2004-01-01

    In 1942 a grievously wounded soldier was forsaken in the "No Mans's Land" for five days. However he totally recovered as his wound had been overrun of maggots. Thus H. Fruchaud decided to apply using of maggots for all infected wounds. PMID:15211995

  10. Reference Man anatomical model

    SciTech Connect

    Cristy, M.

    1994-10-01

    The 70-kg Standard Man or Reference Man has been used in physiological models since at least the 1920s to represent adult males. It came into use in radiation protection in the late 1940s and was developed extensively during the 1950s and used by the International Commission on Radiological Protection (ICRP) in its Publication 2 in 1959. The current Reference Man for Purposes of Radiation Protection is a monumental book published in 1975 by the ICRP as ICRP Publication 23. It has a wealth of information useful for radiation dosimetry, including anatomical and physiological data, gross and elemental composition of the body and organs and tissues of the body. The anatomical data includes specified reference values for an adult male and an adult female. Other reference values are primarily for the adult male. The anatomical data include much data on fetuses and children, although reference values are not established. There is an ICRP task group currently working on revising selected parts of the Reference Man document.

  11. Myth and Modern Man.

    ERIC Educational Resources Information Center

    Patai, Raphael

    Various theories about the purpose of myth are described briefly, and then the place of myth in modern life is explored. Modern man is found to still create his own myths, and his life is still influenced by mythical prototypes and images. Myths, mythical beliefs, and mythical thinking are discovered in socialist, Communist, and totalitarian…

  12. Man--Society--Technology.

    ERIC Educational Resources Information Center

    Taxis, Linda A., Ed.

    The 32nd annual American Industrial Arts Association (AIAA) Convention was held in Louisville in 1970. Topics for the AIAA general session addresses were: (1) "Industrial Arts--The Blender Between Social Form and Technical Function," (2) "Technology and Society: Present and Future Challenges," (3) "A Student-Oriented Industrial Arts," (4) "Man:…

  13. Landing A Man Downtown

    ERIC Educational Resources Information Center

    Waters, W. G., II

    1973-01-01

    Analyzes the urban transport problems in comparison with those involved in a journey to the Moon. Indicates that the problem of enabling man to travel through the inner space of conurbations may prove to be more difficult than the transport problem of space travel. (CC)

  14. Why Man Explores

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This NASA Educational Publication was prepared from a transcript of a panel discussion held on July 2, 1976, in conjunction with the Viking Missions to Mars. The members of the Why Man Explores panel were selected as authorities in classical disciplines relating to exploration.

  15. Colorectal endometriosis: benefits of long-term follow-up in patients who underwent laparoscopic surgery.

    PubMed

    Stepniewska, Anna; Pomini, Paola; Guerriero, Massimo; Scioscia, Marco; Ruffo, Giacomo; Minelli, Luca

    2010-05-01

    In this retrospective cohort study, three groups of patients were included: 60 women who underwent endometriosis surgery with colorectal segmental resection, 40 women with surgical evidence of bowel endometriosis who underwent endometriosis removal without bowel resection, and 55 women affected by moderate or severe endometriosis with at least one endometrioma and deep infiltrating endometriosis but without bowel involvement. The results of a long-term ambulatory follow-up showed that if colorectal endometriosis was present, postoperative pain regression was more frequent, and among patients with bowel endometriosis the rate of recurrence was lower if segmental resection was performed. PMID:19836731

  16. Manned Mars mission

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Terrapin Technologies proposes a Manned Mars Mission design study. The purpose of the Manned Mars Mission is to transport ten people and a habitat with all required support systems and supplies from low Earth orbit (LEO) to the surface of Mars and, after an expedition of three months to return the personnel safely to LEO. The proposed hardware design is based on systems and components of demonstrated high capability and reliability. The mission design builds on past mission experience but incorporates innovative design approaches to achieve mission priorities. These priorities, in decreasing order of importance, are safety, reliability, minimum personnel transfer time, minimum weight, and minimum cost. The design demonstrates the feasibility and flexibility of a waverider transfer module. Information is given on how the plan meets the mission requirements.

  17. Man-Amplifying Exoskeleton

    NASA Astrophysics Data System (ADS)

    Rosheim, Mark E.

    1990-03-01

    This paper describes a design for a man-amplifying exoskeleton, an electrically powered, articulated frame worn by an operator. The design features modular construction and employ anthropomorphic pitch-yaw joints for arms and legs. These singularity-free designs offer a significant advancement over simple pivot-type joints used in older designs. Twenty-six degrees-of-freedom excluding the hands gives the Man-Amplifier its unique dexterity. A five hundred-pound load capacity is engineered for a diverse range of tasks. Potential applications in emergency rescue work, restoring functionality to the handicapped, and military applications ranging from material handling to an elite fighting core are discussed. A bibliography concludes this paper.

  18. Man in space

    NASA Technical Reports Server (NTRS)

    West, J. B.

    1986-01-01

    The Challenger disaster focused attention on the hazards as well as the possibilities of man in space. The physiological effects of prolonged weightlessness include important changes in vestibular, bone, muscle, cardiovascular, blood, renal, and pulmonary function. Much has been learned from US and Soviet experiments, but large areas of ignorance remain. Exceptional opportunities for physiological research are provided by Spacelab, a pressurized laboratory planned as a payload of the Space Shuttle.

  19. Man in space.

    PubMed

    West, J B

    1986-12-01

    The Challenger disaster focused attention on the hazards as well as the possibilities of man in space. The physiological effects of prolonged weightlessness include important changes in vestibular, bone, muscle, cardiovascular, blood, renal, and pulmonary function. Much has been learned from US and Soviet experiments, but large areas of ignorance remain. Exceptional opportunities for physiological research are provided by Spacelab, a pressurized laboratory planned as a payload of the Space Shuttle. PMID:11539062

  20. Man's future in space

    NASA Technical Reports Server (NTRS)

    Freitag, R. F.

    1975-01-01

    Studies evaluating potential operational and commercial uses of space are being conducted, taking into account astronomy, astrophysics, manned bases and laboratories in earth orbit, space colonization, terrestrial communications, space processing and manufacturing, interstellar probes, planetary exploration, and the use of space for terrestrial energy supply. The present status in the exploration of the solar system is examined, giving attention to Jupiter, Venus, Mars, and Mercury. A brief outline of the development of human colonies on Mars is presented.

  1. Typhoon Man-Yi

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Typhoon Man-Yi was pummeling the Japanese island of Okinawa with winds between 230 and 295 kilometers per hour (125-160 knots, 144-184 miles per hour) and heavy rain on the morning of July 13, 2007, when the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Terra satellite captured this image. The immense storm covered hundreds of kilometers with spiraling bands of thunderstorms, though it had lost the distinctive cloud-free eye it exhibited the day before. Typhoons are common in Japan, but powerful typhoons usually strike the island nation later in the year. The Japan Meteorological Agency said that Man-Yi is the fourth typhoon of the 2007 season and may be the most powerful ever observed in the northwest Pacific in July, reported Kyodo News. The Joint Typhoon Warning Center expected the typhoon to strike Kyushu, a southern Japanese island, on July 14, and then curve northeast along the eastern shore of Japan. By the time the storm reaches Tokyo on July 15, it should be degraded to a tropical storm. As of July 13, Typhoon Man-Yi had injured eight and flooded twenty houses in Okinawa, and forced airlines to cancel hundreds of flights, said Kyodo News. The storm was expected to bring heavy rain to Japan's Pacific coast. NASA image created by Jesse Allen, using data provided courtesy of the MODIS Rapid Response team.

  2. Effect of using pump on postoperative pleural effusion in the patients that underwent CABG

    PubMed Central

    Özülkü, Mehmet; Aygün, Fatih

    2015-01-01

    Objective The present study investigated effect of using pump on postoperative pleural effusion in patients who underwent coronary artery bypass grafting. Methods A total of 256 patients who underwent isolated coronary artery bypass grafting surgery in the Cardiovascular Surgery clinic were enrolled in the study. Jostra-Cobe (Model 043213 105, VLC 865, Sweden) heart-lung machine was used in on-pump coronary artery bypass grafting. Off-pump coronary artery bypass grafting was performed using Octopus and Starfish. Proximal anastomoses to the aorta in both on-pump and off-pump techniques were performed by side clamps. The patients were discharged from the hospital between postoperative day 6 and day 11. Results The incidence of postoperative right pleural effusion and bilateral pleural effusion was found to be higher as a count in Group 1 (on-pump) as compared to Group 2 (off-pump). But the difference was not statistically significant [P>0.05 for right pleural effusion (P=0.893), P>0.05 for bilateral pleural effusion (P=0.780)]. Left pleural effusion was encountered to be lower in Group 2 (off-pump). The difference was found to be statistically significant (P<0.05, P=0.006). Conclusion Under the light of these results, it can be said that left pleural effusion is less prevalent in the patients that underwent off-pump coronary artery bypass grafting when compared to the patients that underwent on-pump coronary artery bypass grafting. PMID:27163421

  3. Man and his spaceships

    PubMed Central

    Siefert, Janet L.

    2012-01-01

    The resiliency and adaptive ability of microbial life in real time on Earth relies heavily upon horizontal gene transfer. Based on that knowledge, how likely is earth based microbial life to colonize extraterrestrial targets such as Mars? To address this question, we consider manned and unmanned space exploration, the resident microbiota that is likely to inhabit those vehicles, the adaptive potential of that microbiota in an extraterrestrial setting especially with regards to mobile genetic elements, and the likelihood that Mars like environments could initiate and sustain colonization. PMID:23481263

  4. Syncope on a Hot Summer Day.

    PubMed

    Glancy, David Luke

    2016-06-15

    In a 63-year-old man, episodes of ventricular tachycardia causing syncope and myocardial infarction are the first manifestations of triple vessel coronary disease in the absence of arteriographic evidence of a fresh occlusion. PMID:27131612

  5. Mars manned transportation vehicle

    SciTech Connect

    Perez-Davis, M.E.; Faymon, K.A.

    1987-07-01

    A viable power system technology for a surface transportation vehicle to explore the planet Mars is presented. A number of power traction systems were investigated, and it was found that a regenerative hydrogen-oxygen fuel cell appears to be attractive for a manned Mars rover application. Mission requirements were obtained from the Manned Mars Mission Working Group. Power systems weights, power, and reactants requirements were determined as a function of vehicle weights for vehicles weighing from 6,000 to 16,000 lb (2,722 to 7,257 kg), (Earth weight). The vehicle performance requirements were: velocity, 10 km/hr; range, 100 km; slope climbing capability, 30 deg uphill for 50 km; mission duration, 5 days; and crew, 5. Power requirements for the operation of scientific equipment and support system capabilities were also specified and included in this study. The concept developed here would also be applicable to a Lunar based vehicle for Lunar exploration. The reduced gravity on the Lunar surface, (over that on the Martian surface), would result in an increased range or capability over that of the Mars vehicle since many of the power and energy requirements for the vehicle are gravity dependent.

  6. Thermodynamic correction of particle concentrations measured by underwing probes on fast flying aircraft

    NASA Astrophysics Data System (ADS)

    Weigel, R.; Spichtinger, P.; Mahnke, C.; Klingebiel, M.; Afchine, A.; Petzold, A.; Krämer, M.; Costa, A.; Molleker, S.; Jurkat, T.; Minikin, A.; Borrmann, S.

    2015-12-01

    Particle concentration measurements with underwing probes on aircraft are impacted by air compression upstream of the instrument body as a function of flight velocity. In particular for fast-flying aircraft the necessity arises to account for compression of the air sample volume. Hence, a correction procedure is needed to invert measured particle number concentrations to ambient conditions that is commonly applicable for different instruments to gain comparable results. In the compression region where the detection of particles occurs (i.e. under factual measurement conditions), pressure and temperature of the air sample are increased compared to ambient (undisturbed) conditions in certain distance away from the aircraft. Conventional procedures for scaling the measured number densities to ambient conditions presume that the particle penetration speed through the instruments' detection area equals the aircraft speed (True Air Speed, TAS). However, particle imaging instruments equipped with pitot-tubes measuring the Probe Air Speed (PAS) of each underwing probe reveal PAS values systematically below those of the TAS. We conclude that the deviation between PAS and TAS is mainly caused by the compression of the probed air sample. From measurements during two missions in 2014 with the German Gulfstream G-550 (HALO - High Altitude LOng range) research aircraft we develop a procedure to correct the measured particle concentration to ambient conditions using a thermodynamic approach. With the provided equation the corresponding concentration correction factor ξ is applicable to the high frequency measurements of each underwing probe which is equipped with its own air speed sensor (e.g. a pitot-tube). ξ-values of 1 to 0.85 are calculated for air speeds (i.e. TAS) between 60 and 260 m s-1. From HALO data it is found that ξ does not significantly vary between the different deployed instruments. Thus, for the current HALO underwing probe configuration a parameterisation of

  7. Very-low-dose continuous drip infusion of landiolol hydrochloride for postoperative atrial tachyarrhythmia in patients with poor left ventricular function.

    PubMed

    Morisaki, Akimasa; Hosono, Mitsuharu; Sasaki, Yasuyuki; Hirai, Hidekazu; Sakaguchi, Masanori; Nakahira, Atsushi; Seo, Hiroyuki; Suehiro, Shigefumi

    2012-06-01

    Three patients with poor left ventricular function (left ventricular ejection fraction <30 %) developed postoperative atrial tachyarrhythmia in intensive care. Case 1 was a 64-year-old man who underwent a modified Bentall procedure and mitral valve annuloplasty. Case 2 was a 63-year-old woman who underwent quintuple coronary artery bypass grafting. Case 3 was a 65-year-old man who underwent mitral valve replacement. Preoperative intra-aortic balloon pumping was required in Cases 2 and 3. Excellent heart rate control with no hemodynamic deterioration was achieved in all three cases by very-low-dose continuous drip infusion of landiolol hydrochloride (2-5 μg/kg/min). Very-low-dose continuous drip infusion of landiolol hydrochloride is a safe and useful alternative for the control of perioperative atrial tachyarrhythmias in patients with poor left ventricular function. PMID:22566247

  8. The Nature of Man and Its Implications.

    ERIC Educational Resources Information Center

    Pedrini, D. T.; Gregory, Lura N.

    The many problems presented by the nature of man and in studying man are the focus of this paper which attempts to place these problems in perspective in terms of the past and future. The enigma facing man, that man must study man, is related in an introduction. Freud's, Adler's, and Jung's developments in the study of the nature of man are…

  9. Anesthetic management of patient with Sjogren's syndrome who underwent cesarean section: a case report

    PubMed Central

    Kim, Na Eun; Lee, Jae Hyuk; Lee, Jun Yong

    2016-01-01

    Sjogren's syndrome is one of the most common autoimmune disorders and has a female predominance. Maternal circulating autoantibodies such as anti-Ro/SSA and anti-La/SSB antibodies can cause congenital heart block of fetus, and in severe case, emergency pacemaker implantation may be needed for neonate. Therefore, it is very important to understand maternal and fetal condition and pay attention to the status of the neonate during delivery. In this paper, we present a case of patient with Sjogren's syndrome who underwent cesarean section under spinal anesthesia. PMID:27274376

  10. Rich Man, Poor Man: Developmental Differences in Attributions and Perceptions

    ERIC Educational Resources Information Center

    Sigelman, Carol K.

    2012-01-01

    In an examination guided by cognitive developmental and attribution theory of how explanations of wealth and poverty and perceptions of rich and poor people change with age and are interrelated, 6-, 10-, and 14-year-olds (N = 88) were asked for their causal attributions and trait judgments concerning a rich man and a poor man. First graders, like…

  11. Assessment of beta-cell function and insulin secretion in subjects that underwent renal transplantation.

    PubMed

    Tura, Andrea; Hecking, Manfred; Wolzt, Michael; Saemann, Marcus D; Pacini, Giovanni

    2015-08-01

    In this study we aimed to assess the performance of various indices of beta-cell function derived from oral glucose tolerance test (OGTT) in subjects that underwent renal transplantation. Impaired insulin secretion seems in fact central for development of new onset diabetes after transplantation, but its assessment has not been systematically evaluated. Twenty subjects underwent a 75 g 2h-OGTT for measurement of glucose, insulin, C-peptide. OGTT indices of beta-cell function were either derived by mathematical modeling (yielding the reference index: glucose sensitivity) or were empirical: insulinogenic index (IGI), IGI derived indices, whole shape C-peptide (WHOSH_CP). Indices of beta cell function, showed significant correlation with glucose sensitivity (R(2)=0.40-0.86, all P<;0.003). The majority of beta-cell function indices provided comparable results also when subjects were divided into subgroups according to sex, age, body mass index, mean glycemia. In conclusion, in transplanted subjects OGTT empirical indices are typically acceptable for the estimation of beta-cell function. PMID:26736770

  12. Circulating S100B and Adiponectin in Children Who Underwent Open Heart Surgery and Cardiopulmonary Bypass

    PubMed Central

    Varrica, Alessandro; Satriano, Angela; Frigiola, Alessandro; Giamberti, Alessandro; Tettamanti, Guido; Anastasia, Luigi; Conforti, Erika; Gavilanes, Antonio D. W.; Zimmermann, Luc J.; Vles, Hans J. S.; Li Volti, Giovanni; Gazzolo, Diego

    2015-01-01

    Background. S100B protein, previously proposed as a consolidated marker of brain damage in congenital heart disease (CHD) newborns who underwent cardiac surgery and cardiopulmonary bypass (CPB), has been progressively abandoned due to S100B CNS extra-source such as adipose tissue. The present study investigated CHD newborns, if adipose tissue contributes significantly to S100B serum levels. Methods. We conducted a prospective study in 26 CHD infants, without preexisting neurological disorders, who underwent cardiac surgery and CPB in whom blood samples for S100B and adiponectin (ADN) measurement were drawn at five perioperative time-points. Results. S100B showed a significant increase from hospital admission up to 24 h after procedure reaching its maximum peak (P < 0.01) during CPB and at the end of the surgical procedure. Moreover, ADN showed a flat pattern and no significant differences (P > 0.05) have been found all along perioperative monitoring. ADN/S100B ratio pattern was identical to S100B alone with the higher peak at the end of CPB and remained higher up to 24 h from surgery. Conclusions. The present study provides evidence that, in CHD infants, S100B protein is not affected by an extra-source adipose tissue release as suggested by no changes in circulating ADN concentrations. PMID:26417594

  13. Clinical and morphological features of patients who underwent endovascular interventions for lower extremity arterial occlusive diseases

    PubMed Central

    Arslan, Sakir; Yuksel, Isa Oner; Koklu, Erkan; Cagirci, Goksel; Ureyen, Cagin Mustafa; Bayar, Nermin; Kus, Gorkem

    2015-01-01

    Introduction Patients with peripheral arterial disease (PAD) are at increased risk for all-cause mortality and cardiovascular mortality. Aim To present anatomical and morphological characteristics of patients who underwent endovascular stenting with laboratory and our mid-term results. Material and methods One hundred fifty-three patients (mean age: 62.8, 86% male) who underwent percutaneous intervention of lower extremity arteries were included in the study. Demographic characteristics, medical history, physical examination and laboratory findings of patients were analyzed. Patients’ lesions were classified according to the TransAtlantic Inter-Society Consensus (TASC). Clinical outcomes included complications and mortality, 6-minute walking distance, functional class (NYHA) and patency rates. Results Seventy percent of patients had hypertension, 42% were smokers, 78% had coronary artery disease, 20% had coronary artery bypass grafting, 55% had diabetes mellitus and 71% had dyslipidemia. Six patients with diabetes mellitus and poor wound healing despite medical therapy were treated with stenting leading to alleviation of pain and avoidance of amputation. The initial technical success rate of revascularization was 95.6% (153/160). Our mid-term results show that percutaneous procedures in lower extremity arterial diseases can be performed with low complication and high success rates. Patients’ 6-minute walk distance, ankle/brachial index values, functional class and the status of foot ulcers were evaluated. Conclusions Especially in patients with distal vascular disease, poor wound healing and no chance of surgical revascularization, percutaneous endovascular revascularization may provide good blood flow and prevent amputation. PMID:26161103

  14. Stellar map of neolithic man

    NASA Technical Reports Server (NTRS)

    Pskovskiy, Y. P.

    1978-01-01

    Observations made by ancient man are of great interest to present day astronomers. Drawings made by neolithic man in caves show a surprising sense of perspective. The discoveries in the Fern Grotto in California are of special interest. Photographs of cave drawings are included.

  15. Man Machine Systems in Education.

    ERIC Educational Resources Information Center

    Sall, Malkit S.

    This review of the research literature on the interaction between humans and computers discusses how man machine systems can be utilized effectively in the learning-teaching process, especially in secondary education. Beginning with a definition of man machine systems and comments on the poor quality of much of the computer-based learning material…

  16. Outcome of Patients Underwent Emergency Department Thoracotomy and Its Predictive Factors

    PubMed Central

    Paydar, Shahram; Moghaninasab, Abdoshahid; Asiaei, Elham; Sabetian Fard Jahromi, Golnar; Bolandparvaz, Shahram; Abbasi, Hamidreza

    2014-01-01

    Introduction: Emergency department thoracotomy (EDT) may serve as the last survival chance for patients who arrive at hospital in extremis. It is considered as an effective tool for improvement of traumatic patients’ outcome. The present study was done with the goal of assessing the outcome of patients who underwent EDT and its predictive factors. Methods: In the present study, medical charts of 50 retrospective and 8 prospective cases underwent emergency department thoracotomy (EDT) were reviewed during November 2011 to June 2013. Comparisons between survived and died patients were performed by Mann-Whitney U test and the predictive factors of EDT outcome were measured using multivariate logistic regression analysis. P < 0.05 considered statistically significant. Results: Fifty-eight cases of EDT were enrolled (86.2% male). The mean age of patients was 43.27±19.85 years with the range of 18-85. The mean time duration of CPR was recorded as 37.12±12.49 minutes. Eleven cases (19%) were alive to be transported to OR (defined as ED survived). The mean time of survival in ED survived patients was 223.5±450.8 hours. More than 24 hours survival rate (late survived) was 6.9% (4 cases). Only one case (1.7%) survived to discharge from hospital (mortality rate=98.3%). There were only a significant relation between ED survival and SBP, GCS, CPR duration, and chest trauma (p=0.04). The results demonstrated that initial SBP lower than 80 mmHg (OR=1.03, 95% CI: 1.001-1.05, p=0.04) and presence of chest trauma (OR=2.6, 95% CI: 1.75-3.16, p=0.02) were independent predictive factors of EDT mortality. Conclusion: The findings of the present study showed that the survival rate of trauma patients underwent EDT was 1.7%. In addition, it was defined that falling systolic blood pressure below 80 mmHg and blunt trauma of chest are independent factors that along with poor outcome. PMID:26495363

  17. Thrombokinetics in man

    PubMed Central

    Harker, Laurence A.; Finch, Clement A.

    1969-01-01

    Platelet production, distribution, and destruction have been quantitated in normal man and in selected patients with platelet disorders. In most instances, total production as calculated from the megakaryocyte mass agreed with production estimated from platelet turnover. In patients with megaloblastosis, a discrepancy between these two measurements indicated the presence of ineffective thrombopoiesis. Thrombopoiesis was regulated by (a) alterations in megakaryocyte number, and (b) changes in megakaryocyte volume (produced by changes in endomitosis). The volume-endomitosis changes were closely related to the peripheral platelet count and were a useful indicator of thrombopoietic stimulus. Thrombocytopenic disorders have been classified on the basis of the disturbed physiology into disorders of (a) production (hypoproliferative or ineffective), (b) distribution (splenic pooling), or (c) destruction (immune or consumptive). Less than a twofold increase in platelet production in the presence of significant thrombocytopenia was taken to represent impaired proliferation. Thrombocytosis was classified as reactive or autonomous. Reactive thrombocytosis was consistently associated with a mean megakaryocyte volume and endomitosis less than normal but appropriate for the elevated circulating platelet count. In contrast, the average megakaryocyte volume and nuclear number were always greater than normal in thrombocythemia findings indicating autonomy. Images PMID:5814231

  18. Light in man's environment.

    PubMed

    Marshall, J

    2016-02-01

    Light in the form of solar radiation influenced early civilisations and resulted in the independent development of a number of sun-worshipping dieties. These were of particular importance as hunter gatherers transformed into settled agricultural societies. All artificial light sources were synonymous with fire, and early civilisations began to expand their visual day by burning brands, oil, and candles. Fire-based light sources extended for thousands of years and were still present in the era of gas lighting. Light meant fire risk. The advent of incandescent bulbs and the era of electric lighting really only expanded in the early part of the twentieth century. Fluorescent lighting became available in the 1940s, and today the drive for low energy has resulted in a plethora of novel light sources-in particular, light-emitting diodes (LEDs). Evolution governed the development of the eye in relation to roughly 12 h of light gradually changing to 12 h of darkness. Today almost daylight levels can be achieved abruptly at the flick of a switch. Many studies have demonstrated the spectral dependence of eye health, with the retinal hazard zone associated with wavelengths in the blue, peaking at 441 nm- many of today's low-energy sources peak in this region. Given the increased longevity and artificial light sources emitting at biologically unfriendly wavelengths, attention has to be directed towards light in man's environment as a risk factor in age-related ocular diseases. PMID:26742864

  19. [Incidence of conduction disorders in patients who underwent surgery for hypertrophic obstructive cardiomyopathy].

    PubMed

    Martini, B; Buja, G F; Bassan, L; Rizzardo, P; Canciani, B; Nava, A

    1989-03-01

    Thirteen non-consecutive patients, aging 7 to 61 (average 27) years, underwent left ventricular myotomy-myectomy for a severely symptomatic idiopathic hypertrophic subaortic stenosis (IHSS). In all patients the resting ECG before surgery showed P-R less than 0.18 sec, QRS duration less than 0.11 sec, QRS axis ranging from +10 to +80 degrees. In the immediate post-surgical period 3 patients has complete heart block and 1 had 2nd degree type 2 atrio ventricular block. Lesion was infra-Hisian in 3 patients and intra-Hisian in 1 patient. In the remaining 9 patients an immediate post-surgical left bundle branch block appeared; in 3 out of these patients ECG and an electrophysiologic study documented severe infra-Hisian conduction impairments after an average period of 4 years from surgery. During follow-up 3 patients died suddenly. PMID:2747944

  20. [Anxiety and depression among men and women who underwent percutaneous coronary intervention].

    PubMed

    Furuya, Rejane Kiyomi; Costa, Eliana de Cássia Arantes; Coelho, Mariana; Richter, Vitor César; Dessotte, Carina Aparecida Marosti; Schmidt, André; Dantas, Rosana Aparecida Spadoti; Rossi, Lídia Aparecida

    2013-12-01

    A descriptive, cross-sectional, correlational study aimed to investigate the association of sex and the presence of anxiety and depression after hospital discharge in patients who underwent percutaneous coronary intervention (PCI). Fifty-nine patients undergoing PCI and receiving outpatient treatment in the first seven months after hospital discharge were evaluated. To assess the symptoms of anxiety and depression the Hospital Anxiety and Depression Scale (HADS) was used. To test the possible associations between the variables anxiety, depression and sex the Chi-square test was used with a significance level of 5%. The results indicated a greater number of women with depression and the association between the variables sex and depression was statistically significant. In relation to anxiety, cases were more frequent in males and the association between the variables sex and anxiety was not statistically significant. PMID:24626358

  1. Meralgia paresthetica affecting parturient women who underwent cesarean section -A case report-

    PubMed Central

    Chung, Kum Hee; Ko, Tong Kyun; Park, Chung Hyun; Chun, Duk Hee; Yang, Hyeon Jeong; Gill, Hyun Jue; Kim, Min Ku

    2010-01-01

    Meralgia paresthetica is commonly caused by a focal entrapment of lateral femoral cuteneous nerve while it passes the inguinal ligament. Common symptoms are paresthesias and numbness of the upper lateral thigh area. Pregnancy, tight cloths, obesity, position of surgery and the tumor in the retroperitoneal space could be causes of meralgia paresthetica. A 29-year-old female patient underwent an emergency cesarean section under spinal anesthesia without any problems. But two days after surgery, the patient complained numbness and paresthesia in anterolateral thigh area. Various neurological examinations and L-spine MRI images were all normal, but the symptoms persisted for a few days. Then, electromyogram and nerve conduction velocity test of the trunk and both legs were performed. Test results showed left lateral cutaneous nerve injury and meralgia paresthetica was diagnosed. Conservative treatment was implemented and the patient was free of symptoms after 1 month follow-up. PMID:21286469

  2. [A Patient with Sinking Skin Flap Syndrome who Underwent Perfusion MRI before and after Cranioplasty].

    PubMed

    Kato, Akihito; Morishima, Hiroyuki; Nagashima, Goro

    2016-09-01

    Background:Sinking skin flap syndrome(SSFS)manifests as subjective symptoms, such as headache, dizziness, and undue fatigability, in addition to neurologic symptoms, such as hemiplegia, aphasia, and perceived failure, when the skin over a bone defect sinks in the weeks or months following a decompressive craniectomy. Indeed, these symptoms can improve after a cranioplasty. Case presentation:A 58-year-old woman presented with a disturbance of consciousness. She was found to have a subarachnoid hemorrhage due to a ruptured right middle cerebral artery aneurysm. She underwent a craniotomy with clipping of the affected artery and a decompressive craniectomy on the same day. Post-operatively, the disturbance of consciousness improved, but the left-sided paralysis persisted. She complained of intractable headaches, was disoriented, and a lack of spontaneity emerged as the skin over the bone defect sank. She underwent cranioplasty on the 43rd day after admission, and the symptoms resolved promptly after surgery. Rehabilitation was canceled at the onset of symptoms, but resumed after the symptoms improved. Based on perfusion MRI, the cerebral blood flow(CBF):cerebral blood volume(CBV)ratio of the affected side increased before and after surgery compared with the healthy side. A lumboperitoneal shunt was placed on the 52nd day after admission to manage the hydrocephalus. She was discharged from the hospital with higher brain dysfunction and a mild state of paralysis. Conclusion:The timing of cranioplasty in patients with SSFS has not yet been established, but surgery should be performed before symptoms appear because SSFS impairs rehabilitative efforts. PMID:27605477

  3. Dysphagia among adult patients who underwent surgery for esophageal atresia at birth

    PubMed Central

    Huynh-Trudeau, Valérie; Maynard, Stéphanie; Terzic, Tatjana; Soucy, Geneviève; Bouin, Mickael

    2015-01-01

    BACKGROUND: Clinical experiences of adults who underwent surgery for esophageal atresia at birth is limited. There is some evidence that suggests considerable long-term morbidity, partly because of dysphagia, which has been reported in up to 85% of adult patients who undergo surgery for esophageal atresia. The authors hypothesized that dysphagia in this population is caused by dysmotility and/or anatomical anomalies. OBJECTIVE: To determine the motor and anatomical causes of dysphagia. METHODS: A total of 41 adults, followed at the Esophageal Atresia Clinic at Hôpital Saint-Luc (Montreal, Quebec), were approached to particpate in the present prospective study. Evaluation was completed using upper endoscopy, manometry and barium swallow for the participants who consented. The medical charts of respondents were systematically reviewed from the neonatal period to 18 years of age to assess medical and surgical history. RESULTS: All 41 patients followed at the clinic consented and were included in the study. Dysphagia was present in 73% of patients. Esophagogastroduodenoscopy was performed in 32 patients: hiatal hernia was present in 62% (n=20); esophageal diverticulum in 13% (n=4); macroscopic Barrett esophagus in 31% (n=10); and esophagitis in 19% (n=6). Histological esophagitis was present in 20% and intestinal metaplasia in 10%. There were no cases of dysplagia or adenocarcinoma. Esophageal manometry was performed on 56% of the patients (n=23). Manometry revealed hypomotility in 100% of patients and included an insufficient number of peristaltic waves in 96%, non-propagating peristalsis in 78% and low-wave amplitude in 95%. Complete aperistalsis was present in 78%. The lower esophageal sphincter was abnormal in 12 (52%) patients, with incomplete relaxation the most common anomaly. Of the 41 patients, 29 (71%) consented to a barium swallow, which was abnormal in 13 (45%). The anomalies found were short esophageal dilation in 28%, delay in esophageal emptying in 14

  4. Fundus fluorescein angiographic findings in patients who underwent ventricular assist device implantation.

    PubMed

    Ozturk, Taylan; Nalcaci, Serhad; Ozturk, Pelin; Engin, Cagatay; Yagdi, Tahir; Akkin, Cezmi; Ozbaran, Mustafa

    2013-09-01

    Disruption of microcirculation in various tissues as a result of deformed blood rheology due to ventricular assist device (VAD) implantation causes novel arteriovenous malformations. Capillary disturbances and related vascular leakage in the retina and choroidea may also be seen in patients supported by VADs. We aimed to evaluate retinal vasculature deteriorations after VAD implantation. The charts of 17 patients who underwent VAD implantation surgery for the treatment of end-stage heart failure were retrospectively reviewed. Eight cases (47.1%) underwent pulsatile pump implantation (Berlin Heart EXCOR, Berlin Heart Mediprodukt GmbH, Berlin, Germany); however, nine cases (52.9%) had continuous-flow pump using centrifugal design (HeartWare, HeartWare Inc., Miramar, FL, USA). Study participants were selected among the patients who had survived with a VAD for at least 6 months, and results of detailed ophthalmologic examinations including optic coherence tomography (OCT) and fundus fluorescein angiography (FA) were documented. All of the 17 patients were male, with a mean age of 48.5 ± 14.8 years (15-67 years). Detailed ophthalmologic examinations including the evaluation of retinal vascular deteriorations via FA were performed at a mean of 11.8 ± 3.7 months of follow-up (6-18 months). Mean best-corrected visual acuity and intraocular pressure were found as logMAR 0.02 ± 0.08 and 14.6 ± 1.9 mm Hg, respectively in the study population. Dilated fundoscopy revealed severe focal arteriolar narrowing in two patients (11.8%), and arteriovenous crossing changes in four patients (23.5%); however, no pathological alteration was present in macular OCT scans. In patients with continuous-flow blood pumps, mean arm-retina circulation time (ARCT) and arteriovenous transit time (AVTT) were found to be 16.8 ± 3.0 and 12.4 ± 6.2 s, respectively; whereas those with pulsatile-flow blood pumps were found to be 17.4 ± 3.6 and 14.0 ± 2.1 s in patients (P=0.526 and P=0

  5. Poor man`s parallelism in environmental management

    SciTech Connect

    Johnson, V.M.; Rogers, L.L.

    1995-02-01

    Poor man`s parallelism is a term to describe the harnessing of commonly available computational approaches containing a high degree of implicit or explicit parallelism with distributed computer resources to produce a large gain in processing time. The distinguishing features of poor man`s techniques are their accessibility and relatively low cost. In some circumstances, the clever exploitation of existing hardware and software may achieve as much improvement in the timely completion of tasks as do high-end, state-of-the-art parallel technologies. The ANN-GA approach to the optimization of environmental remediation strategies is an example of poor man`s parallelism: it integrates two well-known computational technologies, artificial neural networks (ANNs) and the genetic algorithm (GA), with a simple scheme for exploiting a network of Unix workstations to solve a nonlinear combinatorial optimization problem. Although this work has been motivated by the need to tame a computational tiger rather than to experiment with different flavors of parallelism, the approach has reached a level of maturity where it is instructive to examine how parallelism is embodied in its various components. It also stands as a demonstration of how even resource-lean organizations can take advantage of parallelism to solve problems.

  6. Acupuncture as an Antiemetic in Children who Underwent Adenoidectomy and/or Tonsillectomy

    PubMed Central

    Özmert, Sengül; Salman, Nergis; Sever, Feyza; Akın, Mine; Saydam, Sibel; Keskin, Gülsen; Akcan, Fatih; Kurt, Devrim Tanıl

    2016-01-01

    Objective Postoperative vomiting (POV) is one of the most common problems following general anaesthesia, and many factors, either solely or in combination, may play a role in aetiology. Acupuncture is a technique that the World Health Organization has accepted as a complementary treatment. This study presents our experience with acupuncture for POV treatment in a study of paediatric tonsillectomy cases. Methods The study included ASA I–II patients (n=70) aged 2–14 years who underwent tonsillectomy and/or adenoidectomy under general anaesthesia. The patients were randomly divided into the following two groups: control and study group. In the study group, an acupuncture needle was intraoperatively applied to the P6 acupuncture point for 20 min. Antiemetics were not administered to either group because of the standard applications in the preoperative period. The patients were postoperatively evaluated by nurses who were unaware about the techniques used in either group. Results No statistically significant difference was determined between the groups with regard to age, sex, nature of the operation, duration of anaesthesia, duration of the operation, surgical method and ASA scores. A statistically significant difference was determined between the groups with respect to vomiting rates. The acupuncture group presented with 0.28-times fewer vomiting episodes than the control group. Conclusion The results of the study demonstrate that acupuncture has an apparent antiemetic efficacy in POV. Its routine use for POV may improve postoperative comfort and reduce drug use for prophylactic or therapeutic purposes. PMID:27366548

  7. Incidence and clinical features of extramedullary multiple myeloma in patients who underwent stem cell transplantation.

    PubMed

    Weinstock, Mathew; Aljawai, Yosra; Morgan, Elizabeth A; Laubach, Jacob; Gannon, Muriel; Roccaro, Aldo M; Varga, Cindy; Mitsiades, Constantine S; Paba-Prada, Claudia; Schlossman, Robert; Munshi, Nikhil; Anderson, Kenneth C; Richardson, Paul P; Weller, Edie; Ghobrial, Irene M

    2015-06-01

    Extramedullary disease (EMD), defined as an infiltrate of clonal plasma cells at an anatomic site distant from the bone marrow, is an uncommon manifestation of multiple myeloma. Six hundred and sixty-three consecutive patients with multiple myeloma who underwent stem cell transplantation between January 2005 and December 2011 were assessed for the presence of EMD. A cohort of 55 patients with biopsy-proven EMD was identified, comprising 8·3% of the total study population. EMD was present at the time of diagnosis in 14·5% of cases and at the time of relapse in 76% of patients. The most common EMD presentations at relapse were liver involvement and pleural effusions. EMD specimens had high expression of CD44 (92%) and moderate expression of CXCR4. The median overall survival from time of myeloma diagnosis was 4·1 years (95% CI: 3·1, 5·1) and the median overall survival from time of EMD diagnosis was 1·3 years (95% CI: 0·8, 2·3). This report demonstrates that the incidence of EMD has not increased with the introduction of novel agents and stem cell transplantation. The most common EMD presentations in the relapsed setting were liver and pleural fluid. The presence of CD44 and CXCR4 expression may represent new markers of EMD that warrant further investigation. PMID:25833301

  8. Clinical significance of preoperative thrombocytosis in patients who underwent radical nephrectomy for nonmetastatic renal cell carcinoma

    PubMed Central

    Choi, Jae Young; Ko, Young Hwii

    2016-01-01

    Purpose The aim of this study was to examine the association of preoperative thrombocytosis with the prognosis of patients with nonmetastatic renal cell carcinoma (RCC). Materials and Methods We conducted a retrospective analysis of 187 patients who underwent a radical nephrectomy for nonmetastatic RCC between July 1997 and June 2009. Thrombocytosis was defined as a platelet count≥400,000 µL, and patients were divided into 2 groups according to presence of preoperative thrombocytosis, and the cancer-specific survival rates and overall survival rates of the 2 groups after radical nephrectomy were compared. Results The mean age of the patients was 56.0±11.7 years and the mean follow-up period was 59.3±42.1 months; there were 20 patients with preoperative thrombocytosis. Thirty patients developed metastases and 9 patients died during the follow-up period. In Kaplan-Meier analysis using a univariate log-rank test, both cancer-specific survival rate (p=0.013) and overall survival rate (p=0.012) showed significant association with preoperative thrombocytosis. Controlling for pathological TNM stage, Fuhrman grade and tumor diameter, the Cox proportional hazards model for cancer-specific survival rates showed that preoperative thrombocytosis was an independent prognostic factor (p=0.025). Conclusions Preoperative thrombocytosis was associated with poorer prognosis in patients with nonmetastatic RCC. Thus, preoperative platelet count may be clinically useful for risk stratification of patients undergoing surgery for nonmetastatic RCC.

  9. Intraocular lens power estimation by accurate ray tracing for eyes underwent previous refractive surgeries

    NASA Astrophysics Data System (ADS)

    Yang, Que; Wang, Shanshan; Wang, Kai; Zhang, Chunyu; Zhang, Lu; Meng, Qingyu; Zhu, Qiudong

    2015-08-01

    For normal eyes without history of any ocular surgery, traditional equations for calculating intraocular lens (IOL) power, such as SRK-T, Holladay, Higis, SRK-II, et al., all were relativley accurate. However, for eyes underwent refractive surgeries, such as LASIK, or eyes diagnosed as keratoconus, these equations may cause significant postoperative refractive error, which may cause poor satisfaction after cataract surgery. Although some methods have been carried out to solve this problem, such as Hagis-L equation[1], or using preoperative data (data before LASIK) to estimate K value[2], no precise equations were available for these eyes. Here, we introduced a novel intraocular lens power estimation method by accurate ray tracing with optical design software ZEMAX. Instead of using traditional regression formula, we adopted the exact measured corneal elevation distribution, central corneal thickness, anterior chamber depth, axial length, and estimated effective lens plane as the input parameters. The calculation of intraocular lens power for a patient with keratoconus and another LASIK postoperative patient met very well with their visual capacity after cataract surgery.

  10. The X-43A hypersonic research aircraft and its modified Pegasus booster rocket recently underwent c

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The first of three X-43A hypersonic research aircraft and its modified Pegasus booster rocket recently underwent combined systems testing while mounted to NASA's NB-52B carrier aircraft at the Dryden Flight Research Center, Edwards, Calif. The combined systems test was one of the last major milestones in the Hyper-X research program before the first X-43A flight. The X-43A flights will be the first actual flight tests of an aircraft powered by a revolutionary supersonic-combustion ramjet ('scramjet') engine capable of operating at hypersonic speeds (above Mach 5, or five times the speed of sound). The 12-foot, unpiloted research vehicle was developed and built by MicroCraft Inc., Tullahoma, Tenn., under NASA contract. The booster was built by Orbital Sciences Corp., Dulles, Va.,After being air-launched from NASA's venerable NB-52 mothership, the booster will accelerate the X-43A to test speed and altitude. The X-43A will then separate from the rocket and fly a pre-programmed trajectory, conducting aerodynamic and propulsion experiments until it descends into the Pacific Ocean. Three research flights are planned, two at Mach 7 and one at Mach 10.

  11. Manned Mars mission cost estimate

    NASA Technical Reports Server (NTRS)

    Hamaker, Joseph; Smith, Keith

    1986-01-01

    The potential costs of several options of a manned Mars mission are examined. A cost estimating methodology based primarily on existing Marshall Space Flight Center (MSFC) parametric cost models is summarized. These models include the MSFC Space Station Cost Model and the MSFC Launch Vehicle Cost Model as well as other modes and techniques. The ground rules and assumptions of the cost estimating methodology are discussed and cost estimates presented for six potential mission options which were studied. The estimated manned Mars mission costs are compared to the cost of the somewhat analogous Apollo Program cost after normalizing the Apollo cost to the environment and ground rules of the manned Mars missions. It is concluded that a manned Mars mission, as currently defined, could be accomplished for under $30 billion in 1985 dollars excluding launch vehicle development and mission operations.

  12. Facing Up to Man's Past.

    ERIC Educational Resources Information Center

    McKean, Kevin; Brownlee, Shannon

    1983-01-01

    Discusses evidence suggesting that man only recently diverged from the apes. The evidence, still disputed by some scientists, has caused many others to revise their thinking as to when and how the human line originated. (JN)

  13. Man, space flight and medicine.

    NASA Technical Reports Server (NTRS)

    Berry, C. A.

    1972-01-01

    Review of experience obtained from space flight to evaluate man's physiological capability to function in space. Results of the Mercury, Gemini, and Apollo programs are presented, with emphasis on the latter. The space medicine requirements which were necessary for assuring man's safe journey into and return from space have resulted in hardware and techniques of great value to terrestrial medicine. The need to monitor the physiologic function of crewmen led to the development of miniaturized, nonirritating, and highly reliable sensors.

  14. Why a Hanging Man Dances.

    PubMed

    Padam, Gurpreet Kaur

    2015-01-01

    "Do you know why a hanging man dances?" asked Mr B. He was once an intensely independent man, now 80 years old and afflicted with end-stage lung disease. He appeared tired, repositioning himself with great effort to sitting at the edge of the bed, tightly holding onto the bed sheets as if clenching to a life that was slowly escaping him. "No. I don't want anything that will make me live longer." PMID:26176577

  15. Newly Developed Sarcopenia as a Prognostic Factor for Survival in Patients who Underwent Liver Transplantation

    PubMed Central

    Ock, So Young; Xu, Weiguang; Lee, Jung-Dong; Lee, Jei Hee; Kim, Hae Jin; Kim, Dae Jung; Lee, Kwan Woo; Han, Seung Jin

    2015-01-01

    Introduction The relationship between a perioperative change in sarcopenic status and clinical outcome of liver transplantation (LT) is unknown. We investigated whether post-LT sarcopenia and changes in sarcopenic status were associated with the survival of patients. Method This retrospective study was based on a cohort of 145 patients from a single transplant center who during a mean of 1 year after LT underwent computed tomography imaging evaluation. The cross-sectional area of the psoas muscle of LT patients was compared with that of age- and sex-matched healthy individuals. The Cox proportional hazards regression model was used to determine whether post-LT sarcopenia and changes in sarcopenic status affect post-LT survival. Results The mean age at LT of the 116 male and 29 female patients was 50.2 ± 7.9 years; the mean follow-up duration was 51.6 ± 32.9 months. All pre-LT patients with sarcopenia still had sarcopenia 1 year after LT; 14 (15%) patients had newly developed sarcopenia. The mean survival duration was 91.8 ± 4.2 months for non-sarcopenic patients and 80.0 ± 5.2 months for sarcopenic patients (log-rank test, p = 0.069). In subgroup analysis, newly developed sarcopenia was an independent negative predictor for post-LT survival (hazard ratio: 10.53, 95% confidence interval: 1.37–80.93, p = 0.024). Conclusion Sarcopenia in LT recipients did not improve in any of the previously sarcopenic patients and newly developed within 1 year in others. Newly developed sarcopenia was associated with increased mortality. Newly developed sarcopenia can be used to stratify patients with regard to the risk of post-LT mortality. PMID:26619224

  16. Vitellogenin Underwent Subfunctionalization to Acquire Caste and Behavioral Specific Expression in the Harvester Ant Pogonomyrmex barbatus

    PubMed Central

    Wurm, Yannick; Riba-Grognuz, Oksana; Studer, Romain A.; Keller, Laurent

    2013-01-01

    The reproductive ground plan hypothesis (RGPH) proposes that the physiological pathways regulating reproduction were co-opted to regulate worker division of labor. Support for this hypothesis in honeybees is provided by studies demonstrating that the reproductive potential of workers, assessed by the levels of vitellogenin (Vg), is linked to task performance. Interestingly, contrary to honeybees that have a single Vg ortholog and potentially fertile nurses, the genome of the harvester ant Pogonomyrmex barbatus harbors two Vg genes (Pb_Vg1 and Pb_Vg2) and nurses produce infertile trophic eggs. P. barbatus, thus, provides a unique model to investigate whether Vg duplication in ants was followed by subfunctionalization to acquire reproductive and non-reproductive functions and whether Vg reproductive function was co-opted to regulate behavior in sterile workers. To investigate these questions, we compared the expression patterns of P. barbatus Vg genes and analyzed the phylogenetic relationships and molecular evolution of Vg genes in ants. qRT-PCRs revealed that Pb_Vg1 is more highly expressed in queens compared to workers and in nurses compared to foragers. By contrast, the level of expression of Pb_Vg2 was higher in foragers than in nurses and queens. Phylogenetic analyses show that a first duplication of the ancestral Vg gene occurred after the divergence between the poneroid and formicoid clades and subsequent duplications occurred in the lineages leading to Solenopsis invicta, Linepithema humile and Acromyrmex echinatior. The initial duplication resulted in two Vg gene subfamilies preferentially expressed in queens and nurses (subfamily A) or in foraging workers (subfamily B). Finally, molecular evolution analyses show that the subfamily A experienced positive selection, while the subfamily B showed overall relaxation of purifying selection. Our results suggest that in P. barbatus the Vg gene underwent subfunctionalization after duplication to acquire caste- and

  17. Management of Catheter-Related Bladder Discomfort in Patients Who Underwent Elective Surgery

    PubMed Central

    Bai, Yunjin; Wang, Xianding; Li, Xiaoqiang; Pu, Chunxiao; Yuan, Haichao; Tang, Yin; Li, Jinhong; Wei, Qiang

    2015-01-01

    Abstract Objective: Despite the various treatment and prevention options for catheter-related bladder discomfort (CRBD), many uncertainties persist in clinical practice. To systematically review the literature on the management of CRBD in patients who underwent surgery. Materials and Methods: Eligible, randomized controlled trials were identified from electronic databases (Cochrane Central Register of Controlled Trials, Medline, and EMBASE) without language restrictions. Selection criteria, methodological rigor, and risk of bias were evaluated by two independent reviewers using Cochrane Collaboration's tools. Results: A total of 1441 patients from 14 articles published between 2005 and 2014 were included. Data heterogeneity precluded meta-analysis; therefore, data were synthesized narratively. Compared with nonurological surgery, CRBD is frequent and occurred immediately after urological surgery, especially after transurethral resection of the bladder tumor (TURBT). Data from included studies suggested that muscarinic antagonists, anesthetics, antiepileptics, and analgesics were associated with significant improvement in symptoms and reducing the incidence of CRBD, compared with placebo. Anticholinergic agents and antiepileptics (gabapentin and pregabalin) administered 1 hour before surgery reduced the incidence and severity of CRBD in the immediate postoperative period. Tramadol and ketamine are centrally acting opioid analgesics with antimuscarinic actions, which effectively prevent CRBD when administered intravenously. Paracetamol administered was also effective for the management of CRBD. Additionally, we perceived that TURBT is the surgical procedure that is the most refractory to treatment. Conclusions: Muscarinic antagonists, anesthetics, antiepileptics, and paracetamol appear to achieve the greatest improvement in the clinical symptoms and a significant reduction in the incidence of CRBD compared with placebo. Although these studies observed a high

  18. The Black Man in American Society.

    ERIC Educational Resources Information Center

    Framingham Public Schools, MA.

    GRADE OR AGES: Junior high school. SUBJECT MATTER: The black man in American society. ORGANIZATION AND PHYSICAL APPEARANCE: There are four major parts each with an overview. The four parts concern a) the African heritage of the black man, b) the American exploitation of the black man, c) the black man's contribution to American society, d) the…

  19. The future of manned spaceflight

    NASA Technical Reports Server (NTRS)

    Cohen, Aaron

    1993-01-01

    This paper examines the future of manned spaceflight in context of past accomplishments and possible future benefits of space exploration. Three technological advances mentioned are a device called the rotating wall vessel, also known as the 'bioreactor,' which allows the study of the growth of cells in three dimensions; the use of microgravity to produce high-quality electronic, magnetic, and superconducting thin films; and mining of helium-3 from the lunar surface for use in future fusion reactions with deuterium. The author then makes recommendations on how NASA should meet the challenges of manned spaceflight.

  20. History of manned space flight

    SciTech Connect

    Baker, D.

    1981-01-01

    This book is the history of all the great moments of failure, tension, drama, euphoria, and success that characterized the beginning of man's adventure in space. It covers the technology and scientific knowledge, the vision, the politics, and the dedication of all those involved in the space program. One chapter is devoted to the experiments and observations of the astronauts as they explored the moon. An integral part of the history of space exploration is the race between Russia and the US to establish man in space. This is included. The book vividly portrays the experiences of the astronauts from Mercury, Gemini, Apollo, Skylab, and the Apollo-Soyuz missions. (SC)

  1. The Sea and Modern Man.

    ERIC Educational Resources Information Center

    Chapman, Frank L.

    This publication is designed for use as part of a curriculum series developed by the Regional Marine Science Project. As an informative text for a three-week unit in marine science for grade six, it considers man's role in using coastal resources and how he affects the marine environments. An ecological approach to nature is emphasized, stressing…

  2. [A man with atypical appendicitis].

    PubMed

    du Pré, Bastiaan C; Akkersdijk, Willem L

    2012-01-01

    A 43-year-old man presented with acute left-sided middle and lower abdominal pain. He was diagnosed with 'left-sided acute appendicitis with non-rotation of the colon'. This is a rare and usually asymptomatic congenital anomaly. PMID:22551755

  3. Man-Made Climatic Changes

    ERIC Educational Resources Information Center

    Landsberg, Helmut E.

    1970-01-01

    Reviews environmental studies which show that national climatic fluctuations vary over a wide range. Solar radiation, earth temperatures, precipitation, atmospheric gases and suspended particulates are discussed in relation to urban and extraurban effects. Local weather modifications and attempts at climate control by man seem to have substantial…

  4. Insects Affecting Man. MP-21.

    ERIC Educational Resources Information Center

    Lawson, Fred A.; Spackman, Everett

    The insects discussed in this document are those which have a direct effect upon humans either through a permanent association, as with lice, or a temporary association in the case of flies, bees, wasps, and spiders. In each case, life cycles and identifying characteristics are presented with remarks about the specific effect incurred by man. (CS)

  5. Man and Machines: Three Criticisms.

    ERIC Educational Resources Information Center

    Schneider, Edward F.

    As machines have become a more common part of daily life through the passage of time, the idea that the line separating man and machine is slowly fading has become more popular as well. This paper examines three critics of change through their most famous works. One of the most popular views of Mary Shelley's "Frankenstein" is that it is a…

  6. 'Botanic Man:' Education or Entertainment?

    ERIC Educational Resources Information Center

    Freeman, Richard

    1979-01-01

    The experience of Thames Television in presenting an educational series during prime time is described. "The Botanic Man," a series on ecology, is a rating success. Several difficulties encountered in collaboration efforts and follow-up activities, including courses and workbook publications, are identified. (JMF)

  7. Humanities II: Man and Revolution.

    ERIC Educational Resources Information Center

    Stanton School District, Wilmington, DE.

    "Man and Revolution," the second syllabus in a sequential program, provides 11th grade students with a humanities course that deals heavily in political theory. The rationale, objectives, guidelines, methods, and arrangement are the same as those described in SO 004 030. The introductory unit, followed by further units, helps students define and…

  8. Man...An Endangered Species?

    ERIC Educational Resources Information Center

    Department of the Interior, Washington, DC.

    The general theme of this 1968 yearbook is that man is a threatened species, facing overpopulation and unbridled technology - both self induced. The presentation is broad, relating to many aspects of conservation and natural resources in the United States in a descriptive, non-technical style. The yearbook is divided into major topics: Land…

  9. SPEECH--MAN'S NATURAL COMMUNICATION.

    ERIC Educational Resources Information Center

    DUDLEY, HOMER; AND OTHERS

    SESSION 63 OF THE 1967 INSTITUTE OF ELECTRICAL AND ELECTRONIC ENGINEERS INTERNATIONAL CONVENTION BROUGHT TOGETHER SEVEN DISTINGUISHED MEN WORKING IN FIELDS RELEVANT TO LANGUAGE. THEIR TOPICS INCLUDED ORIGIN AND EVOLUTION OF SPEECH AND LANGUAGE, LANGUAGE AND CULTURE, MAN'S PHYSIOLOGICAL MECHANISMS FOR SPEECH, LINGUISTICS, AND TECHNOLOGY AND…

  10. Window Design for Manned Spaceflight

    NASA Astrophysics Data System (ADS)

    Lamoure, Richard; Kitchingman, Ian; Novo, Francisco; Sinnema, Gerben

    2012-07-01

    The Window Design for Manned Spacecraft (WDM) project being undertaken by Magna Parva Ltd, under contract with the European Space Agency, aims to develop and improve the current structural integrity verification program for manned spacecraft pressurised windows. A critical review of the existing requirements and current state-of-the-art in spacecraft window design, materials and verification practice is conducted. Possible areas for improvement are identified. An experimental test programme is designed to perform and assess mechanical characterisation methods at material level. Tests are intended to increase familiarity with material testing methods and investigate the effects of sample size, surface finish and load type on material characterisation. Novel methods and their applicability are investigated. Results of characterisation testing will be employed in the design and verification of a breadboard window.

  11. Manned Mars Mission program concepts

    NASA Technical Reports Server (NTRS)

    Hamilton, E. C.; Johnson, P.; Pearson, J.; Tucker, W.

    1988-01-01

    This paper describes the SRS Manned Mars Mission and Program Analysis study designed to support a manned expedition to Mars contemplated by NASA for the purposes of initiating human exploration and eventual habitation of this planet. The capabilities of the interactive software package being presently developed by the SRS for the mission/program analysis are described, and it is shown that the interactive package can be used to investigate the impact of various mission concepts on the sensitivity of mass required in LEO, schedules, relative costs, and risk. The results, to date, indicate the need for an earth-to-orbit transportation system much larger than the present STS, reliable long-life support systems, and either advanced propulsion or aerobraking technology.

  12. RenderMan design principles

    NASA Technical Reports Server (NTRS)

    Apodaca, Tony; Porter, Tom

    1989-01-01

    The two worlds of interactive graphics and realistic graphics have remained separate. Fast graphics hardware runs simple algorithms and generates simple looking images. Photorealistic image synthesis software runs slowly on large expensive computers. The time has come for these two branches of computer graphics to merge. The speed and expense of graphics hardware is no longer the barrier to the wide acceptance of photorealism. There is every reason to believe that high quality image synthesis will become a standard capability of every graphics machine, from superworkstation to personal computer. The significant barrier has been the lack of a common language, an agreed-upon set of terms and conditions, for 3-D modeling systems to talk to 3-D rendering systems for computing an accurate rendition of that scene. Pixar has introduced RenderMan to serve as that common language. RenderMan, specifically the extensibility it offers in shading calculations, is discussed.

  13. A Man With Intractable Convulsion

    PubMed Central

    Xia, Yun; Cutrona, Anthony; Barreiro, Timothy J.

    2015-01-01

    Abstract Tetanus is a rare disease in the United States. Fewer than 40 cases are reported annually because of the high incidence of vaccination. Recognition of the clinical presentations is important because laboratory recovery of pathogen is only 30%, and toxin detection is rare because of consumption at motor neurons. We report a case of tetanus in an elderly man who had a reaction to tetanus vaccination as a child and was nonvaccinated through adult life. PMID:27330266

  14. Manned maneuvering unit latching mechanism

    NASA Technical Reports Server (NTRS)

    Allton, C. S.

    1980-01-01

    The astronaut/Manned Maneuvering Unit interface, which presented a challenging set of requirements for a latching mechanism, is described. A spring loaded cam segment with variable ratio pulley release actuator was developed to meet the requirements. To preclude jamming of the mechanism, special precautions were taken such as spring loaded bearing points and careful selection of materials to resist cold welding. The mechanism successfully passed a number of tests which partially simulated orbital conditions.

  15. Multiple man-machine interfaces

    NASA Technical Reports Server (NTRS)

    Stanton, L.; Cook, C. W.

    1981-01-01

    The multiple man machine interfaces inherent in military pilot training, their social implications, and the issue of possible negative feedback were explored. Modern technology has produced machines which can see, hear, and touch with greater accuracy and precision than human beings. Consequently, the military pilot is more a systems manager, often doing battle against a target he never sees. It is concluded that unquantifiable human activity requires motivation that is not intrinsic in a machine.

  16. Searching for the ideal MAN tool

    SciTech Connect

    Herron, B.L.

    1995-09-01

    The quantity of online documentation and viewing tools is overwhelming, with the World Wide Web, vendor-supported and local-site documentation and tools, etc. Maintaining the information and tools is equally overwhelming. However, statistics show that MAN usage far exceeds usage of other online documentation tools. But as one knows, MAN has its own problems, and at the forefront are MAN`S many inconsistencies. MAN is the standard Unix (and POSIX) tool which provides good summary information for those already familiar with a command. Well-written manual pages provide a good overall documentation. However, when a particular manual becomes too long, it becomes a cumbersome method to use for reading documentation. The paper describes MAN`s problems and the National Energy Research Supercomputer Center requirements for MAN.

  17. Editorial Research Reports on Modern Man.

    ERIC Educational Resources Information Center

    Dickinson, William B., Jr., Ed.

    Nine reports published in this volume study the uneasy coexistence of modern man and the complex society he has wrought. Man's apparent disorganized behavior is attributed to his inability to adapt readily to the charged pace of technological change. To combat the advancement of machine over man, he must, therefore, insist that moral and…

  18. 46 CFR 151.45-3 - Manning.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Manning. 151.45-3 Section 151.45-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-3 Manning. Except as provided for in this section, barges need not be manned unless in the...

  19. 46 CFR 151.45-3 - Manning.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Manning. 151.45-3 Section 151.45-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-3 Manning. Except as provided for in this section, barges need not be manned unless in the...

  20. 46 CFR 151.45-3 - Manning.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Manning. 151.45-3 Section 151.45-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-3 Manning. Except as provided for in this section, barges need not be manned unless in the...

  1. 46 CFR 151.45-3 - Manning.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Manning. 151.45-3 Section 151.45-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-3 Manning. Except as provided for in this section, barges need not be manned unless in the...

  2. 46 CFR 151.45-3 - Manning.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Manning. 151.45-3 Section 151.45-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES BARGES CARRYING BULK LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-3 Manning. Except as provided for in this section, barges need not be manned unless in the...

  3. 77 FR 23806 - Manning Rail, Inc.-Acquisition and Operation Exemption-Manning Grain Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Surface Transportation Board Manning Rail, Inc.--Acquisition and Operation Exemption--Manning Grain Company Manning Rail, Inc. (MRI), a noncarrier, has filed a verified notice of exemption \\1\\ under 49 CFR 1150.31 to acquire from Manning...

  4. Technology and the Nature of Man: Biological Considerations. An Occasional Paper on Man/Society/Technology.

    ERIC Educational Resources Information Center

    Sherwood, Lauralee

    This seminar paper explores biological aspects of the man-technology relationship. From man's beginning and continuing into the future, technology is interwoven extensively in the biological fabric of man. Five facets of the biology-technology interaction are examined: (1) technological innovations enabling man to learn about his biological…

  5. Roles and needs of man in space

    NASA Technical Reports Server (NTRS)

    Von Puttkamer, J.

    1983-01-01

    Human capabilities and requirements on space missions are discussed. Utilitarian and humanistic motivations for manned missions are considered, and a general program of development from easy space access and return, to a permanent LEO presence, to the limited self-sufficiency of man in space, is proposed. Man's potential as scientific observer, operator, and engineer/technician is illustrated with examples from the Apollo and Skylab missions. It is shown that future increases in man's space presence will require significant improvements in habitation technology, crew comfort and safety, operational effectiveness and reliability, and man/machine interactions: man-tended systems must be standardized and adapted to (mainly EVA) human servicing; permanently manned systems must be designed to attain levels of comfort, privacy, and overall habitability more like those expected on the ground.

  6. Manned maneuvering unit technology survey

    NASA Technical Reports Server (NTRS)

    Cook, G. V. O. (Editor)

    1975-01-01

    The preliminary design of the manned maneuvering unit (MMU) for the shuttle is investigated, and the current state of the art in certain technology areas that may find application on the operational EVA shuttle MMU is examined. Three broad areas of technology, namely: (1) mechanical energy storage - i.e., the practicality of utilizing the energy storage capability of either a reaction wheel or a control moment gyro, (2) numerical and alphanumerical displays, and (3) recent electronics developments such as microprocessors and integrated injection logic, were covered.

  7. Effects of weightlessness in man.

    NASA Technical Reports Server (NTRS)

    Berry, C. A.

    1973-01-01

    The program for the Apollo 16 flight was designed to include both safeguards against and investigations of the physiological problems arising from increase in the period of manned space flight. Precautions included the provision of a controlled diet with high potassium content, carefully controlled work loads and work-rest cycles, and an emergency cardiology consultation service, and investigations were made to enable preflight vs postflight comparisons of metabolic, cardiovascular, and central nervous system data. Results of these investigations indicate that adjustment to weightlessness can be satisfactorily assisted by appropriate countermeasures, including attention to diet.

  8. Concurrent Testicular and Bladder Cancer in a 57-year-old Man.

    PubMed

    Han, Esther; Stein, Daniel M; Shi, Dongping; Miocinovic, Ranko

    2015-09-01

    We present a rare finding of concurrent right testis non-seminomatous mixed germ cell tumor and muscle invasive urothelial carcinoma of the bladder in a 57-year-old homeless man. The socioeconomic factors and the disease presentation caused a treatment dilemma in terms of the appropriate type of neoadjuvant chemotherapy. The patient ultimately underwent upfront surgery with retroperitoneal lymph node dissection and radical cystoprostatectomy followed by adjuvant cisplatin-based chemotherapy. PMID:26793541

  9. Chinese Manned Space Utility Project

    NASA Astrophysics Data System (ADS)

    Gu, Y.

    Since 1992 China has been carrying out a conspicuous manned space mission A utility project has been defined and created during the same period The Utility Project of the Chinese Manned Space Mission involves wide science areas such as earth observation life science micro-gravity fluid physics and material science astronomy space environment etc In the earth observation area it is focused on the changes of global environments and relevant exploration technologies A Middle Revolution Image Spectrometer and a Multi-model Micro-wave Remote Sensor have been developed The detectors for cirrostratus distribution solar constant earth emission budget earth-atmosphere ultra-violet spectrum and flux have been manufactured and tested All of above equipment was engaged in orbital experiments on-board the Shenzhou series spacecrafts Space life science biotechnologies and micro-gravity science were much concerned with the project A series of experiments has been made both in ground laboratories and spacecraft capsules The environmental effect in different biological bodies in space protein crystallization electrical cell-fusion animal cells cultural research on separation by using free-low electrophoresis a liquid drop Marangoni migration experiment under micro-gravity as well as a set of crystal growth and metal processing was successfully operated in space The Gamma-ray burst and high-energy emission from solar flares have been explored A set of particle detectors and a mass spectrometer measured

  10. [The man on the portrait].

    PubMed

    Bergstrand, A

    1996-01-01

    Marie Curie was awarded the Nobel Prize in chemistry 1911. During the preceding year a rumour had circulated in Stockholm that she had had an affaire with one of her assistants. She received a letter, in which she was told that there had been strong opposition to her election not on scientific but moral grounds, and that she should not go to Stockholm, because nobody could forsee what reactions her appearance at the prize ceremony could evoke. Emil Kleen, a man of violent temper and radical opinions, reacted strongly to these rumours. He wrote a paper, with a violent attack on Gustaf Retzius, previous professor of Histology at Karolinska Institutet. Rightly or wrongly he suspected him to be the author of the infamous letter. Retzius is described as a dilletant in scientific matters, as a "sexual hyena" and a garroulus old man. This portrait of Retzius is of course most unfair, but the portrait of Emil Kleen by the famous swedish artist Bruno Liljefors is a masterpiece and one of the most valuable of the Swedish Medical Association. PMID:11624972

  11. Leukemia in Animals and Man

    PubMed Central

    Theilen, Gordon H.; Dungworth, Donald L.; Kawakami, Thomas G.

    1968-01-01

    General comparative aspects of leukemia were reviewed. Leukemia in adult cattle occurs frequently within certain multiple case herds. Cattle in these herds often have persistent lymphocytosis and increased numbers of atypical lymphocytes in blood. Attempts are being made to demonstrate the frequency in which this is a “pre-leukemic” or “perileukemic” condition. With the recognition of viral causative agent(s) in chickens, laboratory rodents and cats, there is increased interest in the leukemia of dogs, cattle and other animals, for the disease in these animals may serve as valuable models in the study and isolation of human leukemogenic agents. Epidemiologic and clinicopathologic aspects of animal leukemias share comparative similarities with themselves and with lymphoreticular neoplasms of man. Causative factor(s) probably act on the host, regardless of species, in a similar fashion. It is not likely, but neither improbable, that leukemia in domesticated animals and leukemia in man share common causal relationships. ImagesFigure 1.Figure 2. PMID:18730090

  12. Aerothermodynamics of manned Mars missions

    NASA Technical Reports Server (NTRS)

    Park, Chul; Davies, Carol B.

    1989-01-01

    The aerothermodynamic problems associated with the aerobraking of the spacecraft proposed for the manned Mars mission are studied. The propulsive Delta V necessary at departure from earth and Mars and the velocities of the atmospheric entries into the two planets are deduced. It is shown that the propulsive Delta V can be reduced by increasing the entry velocities and that entry velocities up to about 15 km/sec are appropriate at both earth and Mars. L/D values of 0.8 and 2.0 are found to be necessary at earth and Mars, respectively. Density, pressure, and stagnation-point convective-heat-transfer rates are calculated for the typical aerobraking flights. Assuming the shock layer flow to be in equilibrium, the stagnation-point radiative-heat-transfer rates are calculated to be larger than the convective-heat-transfer rates. The possible impact of ablation, turbulence, and nonequilibrium are discussed.

  13. Manned maneuvering unit: User's guide

    NASA Technical Reports Server (NTRS)

    Lenda, J. A.

    1978-01-01

    The space shuttle will provide an opportunity to extend and enhance the crew's inherent capabilities in orbit by allowing them to operate effectively outside of their spacecraft by means of extravehicular activity. For this role, the shuttle crew will have a new, easier to don and operate space suit with integral life support system, and a self-contained propulsive backpack. The backpack, called the manned maneuvering unit, will allow the crew to operate beyond the confines of the Shuttle cargo bay and fly to any part of their own spacecraft or to nearby free-flying payloads or structure. This independent mobility will be used to support a wide variety of activities including free-space transfer of cargo and personnel, inspection and monitoring of orbital operations, and construction and assembly of large structures in orbit.

  14. Biomarkers of immunotoxicity in man.

    PubMed

    Descotes, J; Nicolas, B; Vial, T; Nicolas, J F

    1996-01-01

    Abstract The immunotoxic consequences of chemical exposures include direct immunotoxicity (namely immunosuppression and immunostimulation), hypersensitivity and autoimmunity, and because the mechanisms involved are markedly different, no single immune parameter is likely to ever predict or assess all three types of immunotoxicity. A fairly large number of immunological endpoints have been proposed for use as biomarkers of immunotoxicity in man. Unfortunately, they are often not sensitive enough and/or poorly standardized, so that their relevance for assessing immunotoxic effects in humans is debatable, and actually debated. Immune-mediated sentinel events detected in individuals with a defined history of chemical exposure, may prove helpful until methodological advances, notably with the introduction of technologies derived from molecular biology, provide reliable parameters to be used as biomarkers of immunotoxicity. PMID:23888916

  15. Fire extinguishers for manned spacecraft

    NASA Astrophysics Data System (ADS)

    Kopylov, S.; Smirnov, N. V.; Tanklevsky, L. T.

    2015-04-01

    Based on an analysis of fires in the oxygen-enriched atmosphere conditions in spacecraft and other sealed chambers of various purposes, the most dangerous groups of fires are identified. For this purpose, groups were compiled to analyze dependences that describe the increase of fire hazard to a critical value. A criterion for determining timely and effective fire extinguishing was offered. Fire experiments in oxygen-enriched atmosphere conditions were conducted, and an array of experimental data on the mass burning rate of materials and their extinguishing by water mist was obtained. Relationships colligating an array of experimental data were offered. Experimental and analytical studies were taken as a basis for hand fire extinguisher implementation for manned spacecraft.

  16. Teleoperator systems for manned space missions

    NASA Technical Reports Server (NTRS)

    Interian, A.

    1972-01-01

    The development of remote mechanical systems to augment man's capabilities in our manned space effort is considered. A teleoperator system extends man's innate intelligence and sensory capabilities to distant hostile and hazardous environments through a manipulator-equipped spacecraft and an RF link. Examined are space teleoperator system applications in the space station/space shuttle program, which is where the most immediate need exists and the potential return is greatest.

  17. Effect of underwing aft-mounted nacelles on the longitudinal aerodynamic characteristics of a high-wing transport airplane

    NASA Technical Reports Server (NTRS)

    Abeyounis, W. K.; Patterson, J. C., Jr.

    1985-01-01

    As part of a propulsion/airframe integration program, tests were conducted in the Langley 16-Foot Transonic Tunnel to determine the longitudinal aerodynamic effects of installing flow through engine nacelles in the aft underwing position of a high wing transonic transfer airplane. Mixed flow nacelles with circular and D-shaped inlets were tested at free stream Mach numbers from 0.70 to 0.85 and angles of attack from -2.5 deg to 4.0 deg. The aerodynamic effects of installing antishock bodies on the wing and nacelle upper surfaces as a means of attaching and supporting nacelles in an extreme aft position were investigated.

  18. Energy exchanges of swimming man

    NASA Technical Reports Server (NTRS)

    Nadel, E. R.; Holmer, I.; Bergh, U.; Astrand, P.-O.; Stolwijk, J. A. J.

    1974-01-01

    Three male swimmers underwent 10-min resting and 20-min swimming (breaststroke) exposures in a swimming flume. Water temperatures in separate exposures were 18, 26, and 33 C. At each water temperature the subjects rested and swam at water velocities of 0.50, 0.75, and 0.95 m/sec, which were designed to produce around 40, 70, and 100% of maximal aerobic power. Measurements were made of esophageal temperature, four skin temperatures, water temperature, heat flow from five local skin surfaces (Hatfield-Turner disks), and oxygen uptake. Calculations were made of mean area-weighted skin temperature and heat flow, metabolic rate, and heat storage. Internal body temperature changes after 20 min of swimming were related to water temperature, swimming intensity, and body composition.

  19. [Anesthetic Management of an Infant who Underwent Awake-intubation for Her Pharyngeal Injury Caused by a Toothbrush].

    PubMed

    Nakano, Yoko; Suzuki, Hiroaki; Arai, Takero; Hashimoto, Yuichi; Okuda, Yasuhisa

    2016-04-01

    A 2-year-and-4-month-old female infant, 12 kg in weight and 90 cm in height fell off from a table, which was about 1 m height with a toothbrush in her mouth without her parents noticing. Urgent CT scan showed that it penetrated the left side of her oropharyngeal wall to the bifurcation of her right carotid artery. According to the initial assessment, carotid artery seemed intact and there seemed to be no sign of CNS involvement. She underwent general anesthesia for further investigation and operation. We could detect vocal code with ease by inserting Glidescope between her tongue and the toothbrush. After the intubation, we administered fentanyl 25 μg rocuronium 15 mg and sevoflulane 3-5% to her, and then she underwent arteriography. The neurosurgeon found no sign of major arterial injury nor traumatic aneurysm nor CNS involvement. She went to the ICU intubated after the removal of the toothbrush. She was extubated 5 days after operation. One of the benefits of the Glidescope is that we can share the visual image, and we chose it this time. When we expect a difficult airway during management for oropharyngeal trauma, we have to consider the way to manage the airway. PMID:27188104

  20. Analysis of Risk Factors Contributing to Recurrence of Papillary Thyroid Carcinoma in Chinese Patients Who Underwent Total Thyroidectomy

    PubMed Central

    Zhang, Wei; Jiao, De; Liu, Baoguo; Sun, Shanping

    2016-01-01

    Background Thyroid cancer is a very common endocrine malignancy, with a rate of total thyroidectomy reported to be up to 27.8%. However, studies analyzing the risk factors that contribute to recurrence of papillary thyroid carcinoma (PTC) after total thyroidectomy in China are still scarce. Material/Methods A total of 536 patients with PTC who underwent total thyroidectomy were retrospectively analyzed. Patients were divided into 2 groups: patients with no recurrent tumor were included in group 1 and patients with tumor recurrence were included in group 2. Results Of 536 patients, 65 patients (12.1%) developed a recurrence of PTC, and 471 patients (87.9%) did not have a recurrence. Univariate analysis indicated that male sex, age ≥50 years, tumor ≥1 cm, poor differentiation, lymph node metastasis, bilaterality, and multifocality may be related to PTC recurrence. Additionally, the results of the logistic regression analysis indicated that male sex, age ≥50 years, primary tumor ≥1 cm, poor dedifferentiation of the tumor, lymph node metastasis, and multifocality may be independent factors contributing to PTC recurrence. Conclusions Male sex, age more than 50 years, primary tumor larger than 1 cm, poor dedifferentiation of the primary tumor, lymph node metastasis, and multifocality were found to increase the risk of PTC recurrence in patients who underwent total thyroidectomy. Additionally, it is necessary to use strictly aggressive and extensive surgery, as well as close monitoring, after the operation. PMID:27084873

  1. The Role of Speech Therapy in Patients Who Underwent Laryngeal Microsurgery due to Phonotraumatic Lesions and Lesions Unrelated to Phonotrauma

    PubMed Central

    Macedo, Claudia de Assis Corrêa de; Macedo, Evaldo Dacheux de; Malafaia, Osvaldo; Catani, Guilherme Simas do Amaral; Ido, Jorge Massaki; Stahlke, Henrique Jorge

    2014-01-01

    Introduction The role of the speech-language pathology in the multiprofessional team dealing with laryngology and the voice has been recognized for a long time. Scientific studies in this field recommend therapies for laryngeal microsurgeries; few of the studies, however, effectively evaluate the result of postoperative speech therapy. Objective To compare speech therapy evaluation and treatment among patients with phonotraumatic lesions and patients with lesions unrelated to phonotrauma who underwent laryngeal microsurgery. Methods This study was performed at IPO Hospital (Paranaense Institute of Otorhinolaryngology, Curitiba, Paraná, Brazil) between February 2010 and February 2011. Of 254 patients who underwent laryngeal microsurgery, 208 patients were included in the study and divided in two groups: group A with phonotraumatic lesions (n = 131) and group B with lesions unrelated to phonotrauma (n = 77). The number of sessions and the functional result after speech therapy were evaluated. Results The number of postoperative phonotherapy sessions after microsurgery was up to 10 sessions in 89.31% and 87.71% for groups A and B, respectively. Phonotherapy treatment showed a better functional evolution in group A (92.37%). Conclusion A significant difference was observed only in functional evolution, which was better in the group with phonotraumatic lesions (p < 0.0001). PMID:25992078

  2. Predictors of survival in patients who underwent video‐assisted thoracic surgery talc pleurodesis for malignant pleural effusion

    PubMed Central

    Yoon, Dong Woog; Choi, Yong Soo; Kim, Jhingook; Kim, Hong Kwan; Zo, Jae Ill; Shim, Young Mog

    2016-01-01

    Background Patients with malignant pleural effusion have a limited life expectancy. An increase in pleural and oncological treatment options and more accurate prognostic evaluation may help individualize treatment strategies. The aim of this study was to identify the prognostic indicators of overall survival (OS) after video‐assisted thoracic surgery (VATS) talc pleurodesis for malignant pleural effusion. Methods We examined the medical records of all consecutive patients with malignant pleural effusion who underwent VATS talc pleurodesis from 2006 to 2008 at the Samsung Medical Center. Univariate and multivariate analyses were used to identify predictors of OS after VATS talc pleurodesis. Results During the study period, 91 patients underwent VATS talc pleurodesis to treat malignant pleural effusion. Early (within 30 days) and late (within 90 days) postoperative mortality rates were 9.9% (9 patients), and 25.3% (23), respectively. Median survival time after VATS talc pleurodesis was 10.5 months. The postoperative respiratory complication rate was 11% (10 patients), and included pneumonia (9) and acute respiratory distress syndrome (4). Multivariate analysis revealed that preoperative chemotherapy (P = 0.012), preoperative radiotherapy (P = 0.003), and Eastern Cooperative Oncology Group (ECOG) performance score 3 or 4 (P = 0.013) were independent risk factors of OS after VATS talc pleurodesis. Conclusions We identified previous chemotherapy or radiotherapy and poor performance status (ECOG 3 or 4) as significant predictors of OS after VATS talc pleurodesis. These prognostic factors can help surgeons select candidates for VATS pleurodesis for malignant pleural effusion.

  3. Recurrent primary mediastinal liposarcoma: A case report

    PubMed Central

    ZHAO, CHUN; ZHANG, FANGBIAO; ZHANG, XIANGYAN; TU, SHAOSONG; WU, ZHIJUN; LI, XIA; XIANG, YINGMING; ZHENG, CHUNHUI; ZENG, QINGHUI

    2016-01-01

    Primary mediastinal liposarcomas are extremely rare. The current study reports the case of a 63-year-old man presenting with a primary liposarcoma arising from the posterior mediastinum. The patient reported a 6-month history of chest pain with increasing dyspnea for 2 months. Enhanced computed tomography revealed a 10×16-cm mass in the posterior mediastinum. Other physical examinations were normal. Radical resection was performed under the agreement of patient. Subsequent pathological analysis indicated a liposarcoma. The patient recovered and was successfully discharged. However, at a follow-up examination 12 months after surgery, recurrence was identified in the anterior mediastinum. Therefore, the patient underwent surgery. The postoperative course was uneventful, however, there was evidence of disease recurrence 2 years after the second surgery. The patient refused any treatment and succumbed after 3 months. PMID:27313694

  4. A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis.

    PubMed

    Rim, Ch'angbum; Lee, Jung-Ae; Gong, Soojung; Kang, Dong Wook; Yang, Heebum; Han, Hyun Young; Kim, Nae Yu

    2016-06-01

    We report the case of a patient with gastric adenocarcinoma with multiple liver metastases. This patient showed complete remission for more than 68 months after S-1/cisplatin combination chemotherapy and radical total gastrectomy. The patient, a 63-year-old man, presented with dyspepsia and difficulty in swallowing. Endoscopic findings showed a huge ulcero-infiltrative mass at the lesser curvature of the mid-body, extending to the distal esophagus. Biopsy revealed a poorly differentiated tubular adenocarcinoma. An abdominal computed tomography scan demonstrated multiple hepatic metastases. S-1/cisplatin combination chemotherapy was initiated, and following completion of six cycles of chemotherapy, the gastric masses and hepatic metastatic lesions had disappeared on abdominal computed tomography. Radical total gastrectomy and D2 lymphadenectomy combined with splenectomy were performed. The patient underwent three cycles of S-1/cisplatin combination chemotherapy followed by tegafur-uracil therapy for 1 year. He remained in complete remission for more than 68 months after surgery. PMID:27433398

  5. A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis

    PubMed Central

    Rim, Ch'angbum; Lee, Jung-Ae; Gong, Soojung; Kang, Dong Wook; Yang, Heebum; Han, Hyun Young

    2016-01-01

    We report the case of a patient with gastric adenocarcinoma with multiple liver metastases. This patient showed complete remission for more than 68 months after S-1/cisplatin combination chemotherapy and radical total gastrectomy. The patient, a 63-year-old man, presented with dyspepsia and difficulty in swallowing. Endoscopic findings showed a huge ulcero-infiltrative mass at the lesser curvature of the mid-body, extending to the distal esophagus. Biopsy revealed a poorly differentiated tubular adenocarcinoma. An abdominal computed tomography scan demonstrated multiple hepatic metastases. S-1/cisplatin combination chemotherapy was initiated, and following completion of six cycles of chemotherapy, the gastric masses and hepatic metastatic lesions had disappeared on abdominal computed tomography. Radical total gastrectomy and D2 lymphadenectomy combined with splenectomy were performed. The patient underwent three cycles of S-1/cisplatin combination chemotherapy followed by tegafur-uracil therapy for 1 year. He remained in complete remission for more than 68 months after surgery. PMID:27433398

  6. Colorectal Cancer With Multiple Metachronous Metastasis Achieving Complete Remission 14 Years After Surgical Resection: Report of a Case

    PubMed Central

    Murono, Koji; Kawai, Kazushige; Kazama, Shinsuke; Tsuno, Nelson H.; Sunami, Eiji; Kitayama, Joji; Watanabe, Toshiaki

    2013-01-01

    A 63-year-old man underwent a colectomy for sigmoid colon cancer in 1997. The upper lobe of his left lung and his left adrenal gland were resected because of metachronous metastases, 7 and 10 years after the initial surgery, respectively. Recurrence of metastases to the middle lobe of the right lung and left adrenal gland were sequentially detected in 2007, and a multimodal therapy, consisting of the combination of radiotherapy and chemotherapy, was conducted since 2007. The chemotherapy included drugs such as FOLFOX, FOLFIRI, bevacizumab, capecitabine, and cetuximab. In 2011, the complete response of all metastatic lesions could be achieved, and no recurrence was detected for more than 1 year. In spite of repeated recurrences, by the combination of surgical resection, chemotherapy, and radiotherapy, the complete response could be achieved 14 years after the initial surgical resection, which can be attributed to the development of new treatment modalities and new agents for colorectal cancer. PMID:23438276

  7. Intravenous levosimendan-norepinephrine combination during off-pump coronary artery bypass grafting in a hemodialysis patient with severe myocardial dysfunction

    PubMed Central

    2010-01-01

    This the case of a 63 year-old man with end-stage renal disease (on chronic hemodialysis), unstable angina and significantly impaired myocardial contractility with low left ventricular ejection fraction, who underwent off-pump one vessel coronary bypass surgery. Combined continuous levosimendan and norepinephrine infusion (at 0.07 μg/kg/min and 0.05 μg/kg/min respectively) started immediately after anesthesia induction and continued for 24 hours. The levosimendan/norepinephrine combination helped maintain an appropriate hemodynamic profile, thereby contributing to uneventful completion of surgery and postoperative hemodynamic stability. Although levosimendan is considered contraindicated in ESRD patients, this case report suggests that combined perioperative levosimendan/norepinephrine administration can be useful in carefully selected hemodialysis patients with impaired myocardial contractility and ongoing myocardial ischemia, who undergo off-pump myocardial revascularization surgery. PMID:20196861

  8. Alveolar-filling growth pattern of sarcomatoid malignant pleural mesothelioma.

    PubMed

    Hayakawa, Takamitsu; Tajima, Shogo; Takanashi, Yusuke; Takahashi, Tsuyoshi; Neyatani, Hiroshi; Funai, Kazuhito

    2016-09-01

    A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63-year-old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with intermingled pulmonary infiltrative shadowing. Biopsy of the pleura under general anaesthesia confirmed the diagnosis of sarcomatoid malignant pleural mesothelioma. The patient underwent left extra-pleural pneumonectomy. Histopathologically, the sarcomatoid spindle tumour cells changed their morphology to polygonal cells in the pulmonary parenchyma and grew upwards, filling the alveolar space without the destruction of its septa, showing an alveolar-filling growth pattern. The current report indicates a case of sarcomatoid pleural mesothelioma that shows an alveolar-filling growth pattern, despite having not been thoroughly categorized in the World Health Organization (WHO) classification. PMID:27516891

  9. [A case of pancreatic carcinoma presenting as pancreaticopleural fistula with pancreatic pleural effusion].

    PubMed

    Sugiyama, Yoshiaki; Tanno, Satoshi; Nishikawa, Tomoya; Nakamura, Kazumasa; Sasajima, Junpei; Koizumi, Kazuya; Mizukami, Yusuke; Karasaki, Hidenori; Kasai, Shinichi; Yoshida, Yukinori; Watanabe, Naomi; Okumura, Toshikatsu; Kohgo, Yutaka

    2010-05-01

    A 63-year-old man was admitted with left pleural effusion, and an amylase level of 30994IU/l. A diagnosis of pancreaticopleural fistula was made, based on the findings of magnetic resonance cholangiopancreatography and endoscopic retrograde pancreatography (ERP). After the placement of an endoscopic naso-pancreatic drainage tube, the pleural effusion markedly reduced. When ERP was performed for internal drainage, the main pancreatic duct and stricture were biopsied and showed pancreatic ductal adenocarcinoma histologically. CT revealed a mass in the head of the pancreas. He underwent pylorus-preserving pancreaticoduodenectomy. To the best of our knowledge this is the first case of pancreatic carcinoma presenting as pancreaticopleural fistula with pancreatic pleural effusion. Clinicians should pay attention to the possible presence of cancer and pancreaticopleural fistula in patients with pancreatic pleural effusion. PMID:20460853

  10. The man and the universe

    NASA Astrophysics Data System (ADS)

    Kolodziejska, Magdalena

    2016-04-01

    The universe has always aroused people's curiosity. It fascinates and at the same time scares in its vastness. Encourages us to reflect of the meaning of human life. This begs the questions: whether there is a life beyond Earth? Whether is it possible that the man is alone in such a large space? These questions still remain unanswered, and topics concerning "the cosmos" constantly evoke many emotions. It is especially fascinating for the youngest students. Quite often, preschoolers can flawlessly name the planets according to their order of appearance in relation to the sun. They are happy to take the fun inspired by journeys into space. Teaching through action is extremely important for the development of the child-man* (Piaget, 2006). The thinking originates primarily from the action. Therefore, students should undertake independent research activities, perform experiments and conduct observations and thus raise questions about the world, looking for meanings and solutions. Adults (a teacher, a person with a passion) are to be the support in the search for knowledge, its processing and cleaning. Its role is to ensure a proper development of environment that is conducive to research activity. The answer to these requirements was to create in the oldest technical school in Poland (Railway Technical College, now Technical College No. 7) the astronomical observatory, which can be used by pupils of Warsaw's kindergartens and schools. There are organized activities for children and youth in this school, as well as trainings for teachers. Younger students during such an interdisciplinary courses are, among others, the opportunity to get acquainted with the construction of the telescope, they can build their own rockets and organize their racing or create your own star constellations. Older students as a result of observations and experiments may confirm or refute the hypothesis that the universe is within each of us. The classes are enriched using applications on

  11. Resistance Pattern of Antibiotics in Patient Underwent Open Heart Surgery with Nosocomial Infection in North of Iran

    PubMed Central

    Davoudi, Alireza; Najafi, Narges; Alian, Shahriar; Tayebi, Atefe; Ahangarkani, Fatemeh; Rouhi, Samaneh; Heydari, Amirhosein

    2016-01-01

    Background: Patients who undergo cardiac surgery appear to be at increased risk for the development of Nosocomial infections (NIs). The development of antibiotic-resistant infections has been associated with significantly greater hospital mortality rates compared to similar infections caused by antibiotic-sensitive pathogens. Objectives: The purpose of this study is survey of Nis and antibiotic resistance patterns of causative bacteria among patients who underwent open heart surgery in the north of Iran during a 2-year period between September 2012 and September 2014. Methods: In this cross-sectional study we evaluated 187 patients that underwent open heart surgery with NIs. Demographic feature, clinical characteristics and risk factors of each infection were recorded. The antibiotic susceptibility test was performed using the Minimum inhibitory concentration (MIC) method according to the standard protocol of Clinical & Laboratory Standards Institute (CLSI). Detection of Extended-spectrum beta-lactamase (ESBL) producing bacteria was performed by the double-disk synergy (DDS) test; also Methicillin-resistant Staphylococcus (MRSA) strains were identified by MRSA Screen Agar. The collected data were analyzed using the SPSS software (ver. 16) and, descriptive statistics were used. Results: Out Of total of 2253 hospitalized patients who underwent open heart surgery, 187(5.05%) patients had NIs. 51.9% of the patients were female. The rates of surgical site infection (SSI), respiratory tract infection, endocarditis, Urinary tract infection (UTI), blood Infection and mediastinitis were 27.80, 25.66%, 17.64, 17.11% 8.55% and 3.20% respectively. E.coli and S.aureus were the most causative agents of NIs. The rate of ESBL-producing bacteria was 14.28- 71.42% among enterobacteriaceae and the rate of MRSA was 54.2% among S.aureus strains. All isolated Acinetobacter.spp were Multi-drug resistance (MDR). Conclusions: We showed that the rate of NIs among these high-risk patients

  12. Prevalence and Prognostic Value of Right Ventricular Systolic Dysfunction in Patients With Constrictive Pericarditis Who Underwent Pericardiectomy.

    PubMed

    Choudhry, Muhammad W; Homsi, Mohamed; Mastouri, Ronald; Feigenbaum, Harvey; Sawada, Stephen G

    2015-08-01

    Impaired right ventricular systolic function (RVSF) may complicate the treatment of constrictive pericarditis (CP) by pericardiectomy, which is a procedure that remains with significant morbidity and mortality. We evaluated RVSF in patients with CP who underwent pericardiectomy to determine the prognostic value of RVSF. RVSF was assessed by measuring Tricuspid Annular Plane Systolic Excursion (TAPSE) in 35 patients (mean age 52 ± 15.4 years) who underwent pericardiectomy. Thirty-one patients (88.6%) had reduced RVSF (TAPSE ≤1.8 cm). Eight patients (23%) had postoperative events (heart failure 3 and hospital mortality 5). Logistic regression showed that concomitant coronary artery bypass grafting (CABG) (p = 0.052), left ventricular ejection fraction (p = 0.059), left atrial diameter (p = 0.028), and TAPSE (p = 0.016) were borderline or significant univariate predictors of events. TAPSE (p = 0.018, odds ratio = 0.605 [0.40 to 0.92]) and CABG (p = 0.033, odds ratio = 20 [1.26 to 315]) were independent predictors of events on multivariate analysis. Stepwise analysis showed that TAPSE provided incremental prognostic value (p = 0.029, chi-square increase 11.6 to 16.3) to the combination of CABG, ejection fraction, and left atrial diameter. Receiver-operating characteristic curve analysis showed an area under the curve of 0.815 for TAPSE. TAPSE of 1.38 cm had a sensitivity of 88% and specificity of 67% for identifying patients with events. TAPSE was also inversely related to the length of hospital stay after pericardiectomy (p = 0.02, R = -0.424). Hence, our study showed that RVSF is frequently reduced in patients with CP who underwent pericardiectomy. In conclusion, TAPSE is an independent predictor of events and provides incremental prognostic value to other clinical and echocardiographic variables. PMID:26048852

  13. Learning Processes in Man, Machine and Society

    ERIC Educational Resources Information Center

    Malita, Mircea

    1977-01-01

    Deciphering the learning mechanism which exists in man remains to be solved. This article examines the learning process with respect to association and cybernetics. It is recommended that research should focus on the transdisciplinary processes of learning which could become the next key concept in the science of man. (Author/MA)

  14. Resources and Man, A Study and Recommendations.

    ERIC Educational Resources Information Center

    National Academy of Sciences, National Research Council, Washington, DC. Div. of Earth Sciences.

    Presented are the results of two years of inquiry by the Committee on Resources and Man established by the National Academy of Sciences. Chapters 1 and 2 pose the problem: since resources are finite, as population increases the ratio of resources to man must eventually fall to an unacceptable level. Chapter 3 considers the possibility of evading…

  15. Man's Size in Terms of Fundamental Constants.

    ERIC Educational Resources Information Center

    Press, William H.

    1980-01-01

    Reviews calculations that derive an order of magnitude expression for the size of man in terms of fundamental constants, assuming that man satifies these three properties: he is made of complicated molecules; he requires an atmosphere which is not hydrogen and helium; he is as large as possible. (CS)

  16. 33 CFR 143.407 - Manning.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Manning. 143.407 Section 143.407 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Standby Vessels § 143.407 Manning. Standby vessels must be...

  17. On the Naturalist Nature of Man

    ERIC Educational Resources Information Center

    Graber, Richard R.

    1969-01-01

    Suggests that man, endowed with intellect, has a moral obligation to revere and to conserve all forms of life. In addition, human resources are to be applied toward ecological investigation and education. A warning is sounded against man's continual plundering of the earth's resources. (LC)

  18. Man Is the Measure...the Measurer.

    ERIC Educational Resources Information Center

    Stone, Mark H.

    1998-01-01

    The science of metrology has moved from man as the measure to man as the measurer. This transformation is documented with examples from the history of metrology. Outcome measures, which rest on the same history of measurement, are units constructed and maintained for their utility, constancy, and generality. (Author/SLD)

  19. Teaching Ideas About Man and the Environment.

    ERIC Educational Resources Information Center

    Phoenix Union High School District, AZ.

    This is a collection of papers which resulted from an assignment given in a seminar dealing with the topic Man and His Environment at Phoenix Union High School, Arizona. The interdisciplinary seminar focused on the relationships between man and his physical environment. Its purpose was to introduce the participants to the spectrum of environmental…

  20. Man and His Physical Environment: Teacher's Manual.

    ERIC Educational Resources Information Center

    Mank, Evans R.

    Building upon Course I, this teaching guide for the first of four units of Course II introduces the secondary student to geographic concepts and generalizations of the physical world to which man has related over time. All units of the second course emphasize the process of development whereby man, coping with given conditions in his physical…

  1. 33 CFR 143.407 - Manning.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Manning. 143.407 Section 143.407 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Standby Vessels § 143.407 Manning. Standby vessels must be crewed in accordance with their certificate...

  2. 33 CFR 143.407 - Manning.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Manning. 143.407 Section 143.407 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Standby Vessels § 143.407 Manning. Standby vessels must be crewed in accordance with their certificate...

  3. 33 CFR 143.407 - Manning.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Manning. 143.407 Section 143.407 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Standby Vessels § 143.407 Manning. Standby vessels must be crewed in accordance with their certificate...

  4. 33 CFR 143.407 - Manning.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Manning. 143.407 Section 143.407 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT Standby Vessels § 143.407 Manning. Standby vessels must be crewed in accordance with their certificate...

  5. Marihuana in Man: Three Years Later

    ERIC Educational Resources Information Center

    Hollister, Leo E.

    1971-01-01

    Reviews three years of research on the effects of marihuana in man. Previously known clinical mental and physical effects have been confirmed. Causes and mechanisms of these effects generally remain undetermined in man and animals. Social implications and long term effects require additional study, although usage appears detrimental. (JM)

  6. Human Behaviour and the Origin of Man

    ERIC Educational Resources Information Center

    Raleigh, M. J.; Washburn, S. L.

    1973-01-01

    The study of origin and evolution of man gives new perspective for understanding his behavior. Physical behaviors such as walking and throwing are results of biological evolution which has not kept pace with sociocultural evolution. Irrational decisions by man in social, cultural, and political fields are results of this brain activity. (PS)

  7. Alternative Frameworks for the Study of Man.

    ERIC Educational Resources Information Center

    Markova, Ivana

    1979-01-01

    Two frameworks for the study of man are discussed. The Cartesian model views man as a physical object. A dialectic framework, with the emphasis on the self, grew out of nineteenth century romanticism and reflects the theories of Hegel. Both models have had an effect on social psychology and the study of interpersonal communication. (BH)

  8. THE MAN MADE WORLD, TEACHER'S MANUAL.

    ERIC Educational Resources Information Center

    Commission on Engineering Education, Washington, DC.

    THIS TEACHER'S MANUAL FOR THE ENGINEERING CONCEPTS CURRICULUM PROJECT'S HIGH SCHOOL COURSE, "THE MAN MADE WORLD," IS THE THIRD DRAFT OF THE EXPERIMENTAL VERSION. THE MATERIAL WRITTEN BY ENGINEERS, SCIENTISTS, AND EDUCATORS, EMPHASIZES ENGINEERING--MAN'S APPLICATION OF SCIENTIFIC PRINCIPLES TO THE CONTROL AND UTILIZATION OF HIS ENVIRONMENT.…

  9. Human capabilities in space. [man machine interaction

    NASA Technical Reports Server (NTRS)

    Nicogossian, A. E.

    1984-01-01

    Man's ability to live and perform useful work in space was demonstrated throughout the history of manned space flight. Current planning envisions a multi-functional space station. Man's unique abilities to respond to the unforeseen and to operate at a level of complexity exceeding any reasonable amount of previous planning distinguish him from present day machines. His limitations, however, include his inherent inability to survive without protection, his limited strength, and his propensity to make mistakes when performing repetitive and monotonous tasks. By contrast, an automated system does routine and delicate tasks, exerts force smoothly and precisely, stores, and recalls large amounts of data, and performs deductive reasoning while maintaining a relative insensitivity to the environment. The establishment of a permanent presence of man in space demands that man and machines be appropriately combined in spaceborne systems. To achieve this optimal combination, research is needed in such diverse fields as artificial intelligence, robotics, behavioral psychology, economics, and human factors engineering.

  10. Manned spacecraft electrical power systems

    NASA Technical Reports Server (NTRS)

    Simon, William E.; Nored, Donald L.

    1987-01-01

    A brief history of the development of electrical power systems from the earliest manned space flights illustrates a natural trend toward a growth of electrical power requirements and operational lifetimes with each succeeding space program. A review of the design philosophy and development experience associated with the Space Shuttle Orbiter electrical power system is presented, beginning with the state of technology at the conclusion of the Apollo Program. A discussion of prototype, verification, and qualification hardware is included, and several design improvements following the first Orbiter flight are described. The problems encountered, the scientific and engineering approaches used to meet the technological challenges, and the results obtained are stressed. Major technology barriers and their solutions are discussed, and a brief Orbiter flight experience summary of early Space Shuttle missions is included. A description of projected Space Station power requirements and candidate system concepts which could satisfy these anticipated needs is presented. Significant challenges different from Space Shuttle, innovative concepts and ideas, and station growth considerations are discussed. The Phase B Advanced Development hardware program is summarized and a status of Phase B preliminary tradeoff studies is presented.

  11. Flight investigation of acoustic and thrust characteristics of several exhaust nozzles installed on underwing nacelles on an F106 airplane

    NASA Technical Reports Server (NTRS)

    Burley, R. R.; Karabinus, R. J.; Freedman, R. J.

    1973-01-01

    To determine flyover noise and thrust and to investigate whether flight velocity significantly affects the noise of exhaust nozzles, a series of flight tests was conducted on three different exhaust nozzles of a type suitable for supersonic transport aircraft. The tests were conducted using an F-106B aircraft modified to carry two underwing nacelles, each containing a calibrated turbojet engine. A flyover altitude of 91 meters (300 ft) and a Mach number of 0.4 provided acoustic data that were repeatable to within + or -1.5 PNdB. Flyover results showed that an auxiliary inlet ejector nozzle was the quietest of the nozzles tested; flight velocity appeared to reduce its noise.

  12. Sepsis associated delirium mimicking postoperative delirium as the initial presenting symptom of urosepsis in a patient who underwent nephrolithotomy

    PubMed Central

    Nag, Deb Sanjay; Chatterjee, Abhishek; Samaddar, Devi Prasad; Singh, Harprit

    2016-01-01

    We report a case of 70 years old male who underwent percutaneous nephrolithotomy for renal calculi. After an uneventful recovery from anaesthesia, the patient developed delirium which manifested as restlessness, agitation, irritability and combative behavior. All other clinical parameters including arterial blood gas, chest X-ray and core temperature were normal and the patient remained haemodynamically stable. But 45 min later the patient developed florid manifestations of septic shock. He was aggressively managed in a protocolized manner as per the Surviving Sepsis Guidelines in the Critical Care Unit and recovered completely. There are no case reports showing postoperative delirium as the only initial presentation of severe sepsis, with other clinical parameters remaining normal. Both urosepsis and sepsis associated delirium have very high mortality. High index of suspicion and a protocolized approach in the management of sepsis can save lives. PMID:27182528

  13. Sepsis associated delirium mimicking postoperative delirium as the initial presenting symptom of urosepsis in a patient who underwent nephrolithotomy.

    PubMed

    Nag, Deb Sanjay; Chatterjee, Abhishek; Samaddar, Devi Prasad; Singh, Harprit

    2016-05-16

    We report a case of 70 years old male who underwent percutaneous nephrolithotomy for renal calculi. After an uneventful recovery from anaesthesia, the patient developed delirium which manifested as restlessness, agitation, irritability and combative behavior. All other clinical parameters including arterial blood gas, chest X-ray and core temperature were normal and the patient remained haemodynamically stable. But 45 min later the patient developed florid manifestations of septic shock. He was aggressively managed in a protocolized manner as per the Surviving Sepsis Guidelines in the Critical Care Unit and recovered completely. There are no case reports showing postoperative delirium as the only initial presentation of severe sepsis, with other clinical parameters remaining normal. Both urosepsis and sepsis associated delirium have very high mortality. High index of suspicion and a protocolized approach in the management of sepsis can save lives. PMID:27182528

  14. Absence of the sternocleidomastoid muscle in a patient that underwent neck dissection for squamous cell carcinoma of the tongue.

    PubMed

    Takahashi, Hidenori; Umeda, Masahiro; Sakakibara, Akiko; Shigeta, Takashi; Minamikawa, Tsutomu; Shibuya, Yasuyuki; Komori, Takahide

    2014-01-01

    The congenital absence of a skeletal muscle is a rare cause of congenital muscular torticollis, and the condition is associated with various unusual anatomical structures. We describe a rare case of congenital absence of the sternocleidomastoid muscle associated with squamous cell carcinoma of the tongue in a patient who underwent neck dissection. In this case, both the external jugular vein and the spinal accessory nerve were absent. However, we found that branches of the C3 nerve extended from the cervical plexus to the trapezius muscle and seemed to be acting as trapezius muscle motor nerves in place of the accessory nerve. After the operation, the patient was able to lift and abduct his right arm, and his shoulder did not droop. PMID:24854995

  15. Retrospective Comparison of Radiological and Clinical Outcomes of PLIF and TLIF Techniques in Patients Who Underwent Lumbar Spinal Posterior Stabilization

    PubMed Central

    Asil, Kiyasettin; Yaldiz, Can

    2016-01-01

    Abstract Degenerative disc disease and spinal stenosis lead to various symptoms. Degeneration of facet joints is added to this degenerative process with aging. Seventy-four patients who were admitted to the Spinal Column Outpatient Clinic of the Neurosurgery Department with a diagnosis of degenerative narrow spinal canal and lumbar spondylolisthesis between 2011 and 2013 and who underwent surgery were included in the study. Our study was conducted with 74 patients of whom 73.0% (n = 54) were female and 27.0% (n = 20) were male. Mean age was 54.86 ± 7.87 years (range 34–74). Although we did not detect a difference between the two surgical methods with regard to clinical improvement, transforaminal lumbar interbody fusion (TLIF) is preferred due to radiological advantages observed one year later, ease of application, and the development of fewer complications. PMID:27124016

  16. Posterior Reversible Encephalopathy Syndrome Resolving Within 48 Hours in a Normotensive Patient Who Underwent Thoracic Spine Surgery

    PubMed Central

    Vakharia, Kunal; Siasios, Ioannis; Dimopoulos, Vassilios G.; Pollina, John

    2016-01-01

    Posterior reversible encephalopathy syndrome (PRES) usually manifests with severe headaches, seizures, and visual disturbances due to uncontrollable hypertension. A patient (age in the early 60s) with a history of renal cell cancer presented with lower-extremity weakness and paresthesias. Magnetic resonance imaging (MRI) of the thoracic spine revealed a T8 vertebral body metastatic lesion with cord compression at that level. The patient underwent preoperative embolization of the tumor followed by posterior resection and placement of percutaneous pedicle screws and rods. Postoperatively, the patient experienced decreased visual acuity bilaterally. Abnormal MRI findings consisted of T2 hyperintense lesions and fluid-attenuated inversion recovery changes in both occipital lobes, consistent with the unique brain imaging pattern associated with PRES. The patient’s blood pressure was normal and stable from the first day of hospitalization. The patient was kept on high-dose steroid therapy, which was started intraoperatively, and improved within 48 hours after symptom onset. PMID:26858804

  17. The association between orthostatic hypotension and cognitive state among adults 65 years and older who underwent a comprehensive geriatric assessment.

    PubMed

    Punchick, Boris; Freud, Tamar; Press, Yan

    2016-07-01

    The prevalence of cognitive impairment and orthostatic hypotension (OH) increases with age, but the results of studies that assessed possible associations between them are inconsistent.The aim of this study is to assess possible associations between cognitive impairment and OH in patients ≥65 years of age who underwent a comprehensive geriatric assessment.A retrospective analysis was conducted of the computerized medical records of the study population from 2005 to 2013. Data collected included blood pressure measurements that enabled the calculation of OH, results of the mini-mental state examination (MMSE), results of the Montreal cognitive assessment (MoCA) test, and cognitive diagnoses that were determined over the course of the assessment.The rate of OH in the study population of 571 adults was 32.1%. The mean MMSE score was 22.5 ± 5.2 among participants with OH and 21.6 ± 5.8 among those without OH (P = 0.09). The absence of a significant association between OH and MMSE remained after adjusting the MMSE score for age and education level. The mean MoCA score was 16.4 ± 5.0 among participants with OH and 16.4 ± 4.8 among those without (P = 0.33). The prevalence of OH was 39% among participants without cognitive impairment, 28.9% among those with mild cognitive impairment (MCI), and 30.6% among those with dementia (P = 0.13).There was no association between OH and cognitive impairment in adults who underwent a comprehensive geriatric assessment. PMID:27442658

  18. The ancestry and affiliations of Kennewick Man.

    PubMed

    Rasmussen, Morten; Sikora, Martin; Albrechtsen, Anders; Korneliussen, Thorfinn Sand; Moreno-Mayar, J Víctor; Poznik, G David; Zollikofer, Christoph P E; Ponce de León, Marcia S; Allentoft, Morten E; Moltke, Ida; Jónsson, Hákon; Valdiosera, Cristina; Malhi, Ripan S; Orlando, Ludovic; Bustamante, Carlos D; Stafford, Thomas W; Meltzer, David J; Nielsen, Rasmus; Willerslev, Eske

    2015-07-23

    Kennewick Man, referred to as the Ancient One by Native Americans, is a male human skeleton discovered in Washington state (USA) in 1996 and initially radiocarbon dated to 8,340-9,200 calibrated years before present (BP). His population affinities have been the subject of scientific debate and legal controversy. Based on an initial study of cranial morphology it was asserted that Kennewick Man was neither Native American nor closely related to the claimant Plateau tribes of the Pacific Northwest, who claimed ancestral relationship and requested repatriation under the Native American Graves Protection and Repatriation Act (NAGPRA). The morphological analysis was important to judicial decisions that Kennewick Man was not Native American and that therefore NAGPRA did not apply. Instead of repatriation, additional studies of the remains were permitted. Subsequent craniometric analysis affirmed Kennewick Man to be more closely related to circumpacific groups such as the Ainu and Polynesians than he is to modern Native Americans. In order to resolve Kennewick Man's ancestry and affiliations, we have sequenced his genome to ∼1× coverage and compared it to worldwide genomic data including for the Ainu and Polynesians. We find that Kennewick Man is closer to modern Native Americans than to any other population worldwide. Among the Native American groups for whom genome-wide data are available for comparison, several seem to be descended from a population closely related to that of Kennewick Man, including the Confederated Tribes of the Colville Reservation (Colville), one of the five tribes claiming Kennewick Man. We revisit the cranial analyses and find that, as opposed to genome-wide comparisons, it is not possible on that basis to affiliate Kennewick Man to specific contemporary groups. We therefore conclude based on genetic comparisons that Kennewick Man shows continuity with Native North Americans over at least the last eight millennia. PMID:26087396

  19. End-of-Life Care Patterns Associated with Pediatric Palliative Care among Children Who Underwent Hematopoietic Stem Cell Transplant.

    PubMed

    Ullrich, Christina K; Lehmann, Leslie; London, Wendy B; Guo, Dongjing; Sridharan, Madhumitha; Koch, Richard; Wolfe, Joanne

    2016-06-01

    Stem cell transplantation (SCT) is an intensive therapy offering the possibility of cure for life-threatening conditions but with risk of serious complications and death. Outcomes associated with pediatric palliative care (PPC) for children who undergo SCT are unknown. Therefore, we evaluated whether PPC consultation is associated with differences in end-of-life (EOL) care patterns for children who underwent SCT and did not survive. Medical records of children who underwent SCT at Boston Children's Hospital/Dana-Farber Cancer Institute for any indication from September 2004 to December 2012 and did not survive were reviewed. Child demographic and clinical characteristics and PPC consultation and EOL care patterns were abstracted. Children who received PPC (PPC group) were compared with those who did not (non-PPC group). Children who received PPC consultation (n = 37) did not differ from the non-PPC group (n = 110) with respect to demographic or clinical characteristics, except they were more likely to have undergone unrelated allogeneic SCT (PPC, 68%; non-PPC, 39%; P = .02) or to have died from treatment-related toxicity (PPC, 76%; non-PPC, 54%; P = .03). PPC consultation occurred at a median of .7 months (interquartile range [IQR], .4 to 4.2) before death. PPC consultations most commonly addressed goals of care/decision-making (92%), psychosocial support (84%), pain management (65%), and non-pain symptom management (70%). Prognosis discussions (ie, the likelihood of survival) occurred more commonly in the PPC group (PPC, 97%; non-PPC, 83%; P = .04), as did resuscitation status discussions (PPC, 88%; non-PPC, 58%; P = .002). These discussions also occurred earlier in the PPC group, for prognosis a median of 8 days (IQR, 4 to 26) before death compared with 2 days (IQR, 1 to 13) in the non-PPC group and for resuscitation status a median of 7 days (IQR, 3 to 18) compared with 2 days (IQR, 1 to 5) in the non-PPC group (P < .001 for both of the timing

  20. The Ancestry and Affiliations of Kennewick Man

    PubMed Central

    Rasmussen, Morten; Poznik, G. David; Zollikofer, Christoph P. E.; de León, Marcia Ponce; Allentoft, Morten E.; Moltke, Ida; Jónsson, Hákon; Valdiosera, Cristina; Malhi, Ripan S.; Orlando, Ludovic; Bustamante, Carlos D.; Stafford, Thomas W.; Meltzer, David J.; Nielsen, Rasmus; Willerslev, Eske

    2016-01-01

    Kennewick Man, referred to as the Ancient One by Native Americans, is a male human skeleton discovered in Washington state (USA) in 1996 and initially radiocarbon-dated to 8340–9200 calibrated years BP1. His population affinities have been the subject of scientific debate and legal controversy. Based on initial study of cranial morphology it was asserted that Kennewick Man was neither Native American nor closely related to the Claimant Plateau tribes of the Pacific Northwest, who claimed ancestral relationship and requested repatriation under the Native American Graves Protection and Repatriation Act (NAGPRA). The morphological analysis was important to judicial decisions that Kennewick Man was not Native American and that therefore NAGPRA did not apply. Instead of repatriation, additional studies of the remains were permitted2. Subsequent craniometric analysis affirmed Kennewick Man to be more closely related to circumpacific groups such as the Ainu and Polynesians than he is to modern Native Americans2. In order to resolve Kennewick Man’s ancestry and affiliations, we have sequenced his genome to ~1× coverage and compared it to worldwide genomic data including the Ainu and Polynesians. We find that Kennewick Man is closer to modern Native Americans than to any other population worldwide. Among the Native American groups for whom genome wide data is available for comparison, several appear to be descended from a population closely related to that of Kennewick Man, including the Confederated Tribes of the Colville Reservation (Colville), one of the five tribes claiming Kennewick Man. We revisit the cranial analyses and find that, as opposed to genomic-wide comparisons, it is not possible on that basis to affiliate Kennewick Man to specific contemporary groups. We therefore conclude based on genetic comparisons that Kennewick Man shows continuity with Native North Americans over at least the last eight millennia. PMID:26087396

  1. Construction of manned lunar surface sites

    NASA Astrophysics Data System (ADS)

    Yuzawa, Yoshinori; Horie, Michihiko; Nakamura, Tetsuya; Amagata, Raita; Honda, Tetsuya

    1991-07-01

    A review is conducted on manned lunar surface sites to be constructed in around 2010 to conduct various experiments and observations on the lunar surface in a short time prior to developing permanent lunar bases. Methods of construction and operation of manned lunar surface sites are established, taking requirements from the mission parts and shipping mean constraints. Review results of mission requirements and operation profiles are presented. Experiment subjects, structures and outlines of subsystems, weight balance, electric power balance and functional block diagram of the manned lunar surface sites are presented. Conceptual drawings of air-lock and roving vehicle, operation profiles and conceptual drawing of lunar surface sites are shown.

  2. MAN or FA from n-butane

    SciTech Connect

    Di Cio, A.; Verde, L.

    1985-08-01

    Unsaturated polyester resins were first produced mostly from fumaric acid (FA) rather than from maleic anhydride (MAN). This is perfectly understandable if we consider that, using fumaric acid as raw material, polycondensates with a more homogeneous (less branched) structure are obtained, thus producing resins characterized by a more uniform and reproducible chemical and mechanical properties. Presently, for economical reasons, fumaric acid is used marginally as a MAN substitute in the production of polyester resins. These resins account for a major share (50%) of the overall MAN consumption in the U.S. and in Western Europe.

  3. A Study of Psychological Distress in Two Cohorts of First-Year Medical Students that Underwent Different Admission Selection Processes

    PubMed Central

    Yusoff, Muhamad Saiful Bahri; Rahim, Ahmad Fuad Abdul; Baba, Abdul Aziz; Ismail, Shaiful Bahari; Esa, Ab Rahman

    2012-01-01

    Background: Medical training is often regarded as a stressful period. Studies have previously found that 21.6%–50% of medical students experience significant psychological distress. The present study compared the prevalence and levels of psychological distress between 2 cohorts of first-year medical students that underwent different admission selection processes. Methods: A comparative cross-sectional study was conducted by comparing 2 cohorts of first-year medical students; 1 group (cohort 1) was selected based purely on academic merit (2008/2009 cohort) and the other group (cohort 2) was selected based on academic merit, psychometric assessment, and interview performance (2009/2010 cohort). Their distress levels were measured by the General Health Questionnaire, and scores higher than 3 were considered indicative of significant psychological distress. Results: The prevalence (P = 0.003) and levels (P = 0.001) of psychological distress were significantly different between the 2 cohorts. Cohort 1 had 1.2–3.3 times higher risk of developing psychological distress compared to cohort 2 (P = 0.007). Conclusion: Cohort 2 had better psychological health than cohort 1 and was less likely to develop psychological distress. This study provided evidence of a potential benefit of multimodal student selection based on academic merit, psychometric assessment, and interview performance. This selection process might identify medical students who will maintain better psychological health. PMID:23610547

  4. CORRELATION BETWEEN PRE AND POSTOPERATIVE UPPER DIGESTIVE ENDOSCOPY IN PATIENTS WHO UNDERWENT ROUX-EN-Y GASTROJEJUNAL BYPASS

    PubMed Central

    CZECZKO, Leticia Elizabeth Augustin; CRUZ, Manoela Aguiar; KLOSTERMANN, Flávia Caroline; CZECZKO, Nicolau Gregori; NASSIF, Paulo Afonso Nunes; CZECZKO, Alexandre Eduardo Augusto

    2016-01-01

    Background: Bariatric operations have variable range of complications and postoperative benefits. Gastroesophageal reflux is considered potential factor that may result in damage to the esophageal mucosa and this subject is quite controversial in the literature. Aim : To evaluate patients who underwent to Roux-en-Y gastrojejunal bypass correlating epidemiologic and endoscopic findings in pre and postoperative periods. Method : A retrospective, paired study which evaluated 110 patients. Inclusion criteria were formal indication for bariatric surgery and patients with pre and postoperative endoscopy. Exclusion criteria were previous bariatric surgery, patients subjected to other types of bariatric surgery and those who had no pre or postoperative upper digestive endoscopy. The epidemiological variables were: sex, age, body mass index, type 2 diabetes mellitus or impaired glucose tolerance, and preoperative dyslipidemia. Results : The preoperative upper endoscopy was normal in 26.4% of the patients. Among endoscopic alterations, the hiatus hernia was the most prevalent followed by non-erosive gastritis. The postoperative upper endoscopy was normal in 40.9% and stenosis was the most prevalent followed by marginal ulcer. Correlation on pre and postoperative endoscopies, was found 100% reduction of hiatal hernias and 88% of esophagitis. There was no statistical significance in relationship to anastomotic stenosis with preoperative other variables. Conclusions: There was significant decrease in postoperative hiatus hernia, erosive esophagitis, non-erosive esophagitis, erosive gastritis and non-erosive gastritis with the operation. Stenosis of the gastrojejunostomy anastomosis was the most prevalent postoperative complication with no correlation with preoperative variables. PMID:27120737

  5. Complications after video-assisted thoracic surgery in patients with pulmonary nontuberculous mycobacterial lung disease who underwent preoperative pulmonary rehabilitation

    PubMed Central

    Morino, Akira; Murase, Kazuma; Yamada, Katsuo

    2015-01-01

    [Purpose] Video-assisted thoracic surgery and preoperative pulmonary rehabilitation are effective in preventing postoperative complications in patients with cardiopulmonary disease. The present study aims to elucidate the presence of postoperative pneumonia and atelectasis in patients with nontuberculous mycobacterial lung disease who underwent lung resection with video-assisted thoracic surgery and preoperative pulmonary rehabilitation. [Subjects and Methods] Nineteen patients with nontuberculous mycobacterial lung disease who had undergone lung resection with video-assisted thoracic surgery and preoperative pulmonary rehabilitation were enrolled in this study. The presence of postoperative pneumonia and atelectasis was evaluated, and preoperative and postoperative pulmonary functions were compared. [Results] Postoperative pneumonia and postoperative atelectasis were not observed. Decreases of pulmonary function were 5.9% (standard deviation, 8.5) in forced vital capacity (percent predicted) and 9.6% (standard deviation, 11.1) in forced expiratory volume in 1 s (percent predicted). [Conclusion] The present study indicates that the combination of lung resection with video-assisted thoracic surgery and preoperative pulmonary rehabilitation in patients with nontuberculous mycobacterial lung disease may be effective in preventing postoperative complications. PMID:26357436

  6. A Case of Gastrointestinal Stromal Tumor That Underwent Endoscopic Ultrasound-Guided Aspiration with a 25-Gauge Biopsy Needle

    PubMed Central

    Tomizawa, Minoru; Shinozaki, Fuminobu; Motoyoshi, Yasufumi; Sugiyama, Takao; Yamamoto, Shigenori; Ishige, Naoki

    2016-01-01

    Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is performed to obtain specimens for pathological analysis. For this procedure, 19-gauge (19G), 22-guage (22G), and 25-guage (25G) needles are available. The needles are classified into aspiration type and biopsy type. A 56-year-old woman underwent upper gastrointestinal endoscopy that showed a 38-mm-diameter submucosal tumor. The elevated lesion was diagnosed as a submucosal tumor of the stomach. Contrast-enhanced computed tomography showed a low-density area on the luminal surface of the gastric wall, which was covered with a thin layer of gastric mucosa. EUS showed a hypoechoic lesion in the submucosal layer. Color Doppler image showed a pulsating vascular signal extending into the center of the hypoechoic lesion from the periphery. EUS-FNA was performed with a 25G biopsy needle. The specimen tissue consisted of spindle-shaped cells. The cells were positive for CD117 and CD34. The submucosal tumor was diagnosed as a gastrointestinal stromal tumor.

  7. Factors Associated With Late Specialized Rehabilitation among Veterans with Lower Extremity Amputation Who Underwent Immediate Postoperative Rehabilitation

    PubMed Central

    Kurichi, Jibby E.; Xie, Dawei; Kwong, Pui L.; Bates, Barbara E.; Vogel, W. Bruce; Stineman, Margaret G.

    2011-01-01

    Objective To determine what patient- and facility-level characteristics drive late specialized rehabilitation among veterans who already received immediate postoperative services. Design Data were obtained from 8 administrative databases for 2,453 patients who underwent lower extremity amputation in Veterans Affairs Medical Centers in 2002-2004. A Cox proportional hazards model was used to determine the hazards ratios and 95% confidence intervals of the factors associated with days to readmission for late services after discharge from the surgical hospitalization. Results There were 2,304 patients who received only immediate postoperative services, while 152 also received late specialized rehabilitation. After adjustment, veterans who were less disabled physically, residing in the South Central compared to the Southeast region, and had their surgeries in CARF accredited facilities were all more likely to receive late services. The hazards ratios for type of immediate postoperative rehabilitation were not constant over time. At hospital discharge, there was no difference in receipt, however, after 3 months, those who received early specialized rehabilitation were significantly less likely to receive late services. Conclusion The factors associated with late specialized rehabilitation were due mainly to facility-level characteristics and care process variables. Knowledge of these factors may help with decision-making policies regarding CARF accredited units. PMID:21389847

  8. The advantages of early trauma team activation in the management of major trauma patients who underwent exploratory laparotomy

    PubMed Central

    Yoo, Youngsun

    2014-01-01

    Purpose Trauma team activation (TTA) has been shown to have fundamental impact on trauma patients' outcomes. The purpose of this study was to evaluate the short-term outcomes of use of a new TTA protocol in the management of major trauma patients who underwent exploratory laparotomy. Methods The medical records of trauma patients who had been treated by the new TTA protocol (NT) over 18 months were compared with those of trauma patients treated by the old TTA protocol (OT) over 18 months. Comparisons between the two groups in terms of the time interval between accident and emergency room (ER) arrival, between ER arrival and CT scanning, between ER arrival and operating room (OR) presentation, between accident and OR presentation, mean intensive care unit (ICU) stay, mean hospital stay, mortality within 24 hours, mean mortality within one month, and overall mortality were performed using the Pearson chi-squared test and Student t-test. Results The time interval between accident and ER arrival, between ER arrival and CT scanning, between ER arrival and OR presentation, and between accident and OR presentation was found to have decreased significantly with the use of NT compared to OT. However, the mean ICU stay, mean hospital stay, mortality within 24 hours, mortality within one month, and overall mortality were found not to have improved. Conclusion While initiation of early TTA can shorten the time interval in the management of trauma patients, it may not improve patient outcomes. PMID:25485240

  9. Synergistic Man: Outcome Model for Counselors

    ERIC Educational Resources Information Center

    Rousseve, Ronald J.

    1973-01-01

    Drawing on the insights of Ruth Benedict and Abraham Maslow in their search for an ethical gauge by which to rate personal-social health, this article proposes synergistic man'' as the desired outcome model for counselors. (Author)

  10. Many Manly Men Avoid Needed Health Care

    MedlinePlus

    ... fullstory_158551.html Many Manly Men Avoid Needed Health Care Gender stereotypes can have dangerous consequences, research suggests ... traditional masculine ideals were less likely to seek health care, more likely to downplay symptoms, and had worse ...

  11. QX MAN: Q and X file manipulation

    NASA Technical Reports Server (NTRS)

    Krein, Mark A.

    1992-01-01

    QX MAN is a grid and solution file manipulation program written primarily for the PARC code and the GRIDGEN family of grid generation codes. QX MAN combines many of the features frequently encountered in grid generation, grid refinement, the setting-up of initial conditions, and post processing. QX MAN allows the user to manipulate single block and multi-block grids (and their accompanying solution files) by splitting, concatenating, rotating, translating, re-scaling, and stripping or adding points. In addition, QX MAN can be used to generate an initial solution file for the PARC code. The code was written to provide several formats for input and output in order for it to be useful in a broad spectrum of applications.

  12. Laser Pyro System Standardization and Man Rating

    NASA Technical Reports Server (NTRS)

    Brown, Christopher W.

    2004-01-01

    This viewgraph presentation reviews an X-38 laser pyro system standardization system designed for a new manned rated program. The plans to approve this laser initiation system and preliminary ideas for this system are also provided.

  13. Mission analyses for manned flight experiments

    NASA Technical Reports Server (NTRS)

    Orth, J. E.

    1973-01-01

    The investigations to develop a high altitude aircraft program plan are reported along with an analysis of manned comet and asteroid missions, the development of shuttle sortie mission objectives, and an analysis of major management issues facing the shuttle sortie.

  14. Efficacy of Prothrombin Complex Concentrate Treatment in Patients with Liver Coagulopathy Who Underwent Various Invasive Hepatobiliary and Gastrointestinal Procedures

    PubMed Central

    Lesmana, Cosmas Rinaldi A.; Cahyadinata, Lidwina; Pakasi, Levina S.; Lesmana, Laurentius A.

    2016-01-01

    Background Prothrombin complex concentrates (PCCs) containing prothrombin, factors VII, IX, and X, as well as the inhibitors protein C and S have been used as an emergent reversal for oral anticoagulation therapy. The use of PCCs in hepatobiliary disorder patients or patients with liver coagulopathy who need to undergo invasive procedures has not been well studied. Objective To evaluate the efficacy of PCC treatment in order to control or prevent bleeding complications in patients with liver coagulopathy who undergo various invasive procedures. Methods This was a prospective, open-label, non-randomized, before-and-after study in patients with hepatobiliary disorders who underwent invasive procedures accompanied by liver impairment and received PCC injection (Cofact®, Sanquin, The Netherlands). Patients with coagulopathy from various causes were recruited consecutively. Data collected were the episodes of bleeding, liver function test and the international normalized ratio (INR) before and after PCC therapy. The primary endpoint was INR change after treatment, while secondary endpoints included bleeding control and bleeding event after treatment. Results Thirty patients (17 men, 13 women) were enrolled. Patients’ mean age was 57.0 + 15.5 years. Liver cirrhosis was found in 14 patients (46.7%). The procedures consisted of liver biopsy, liver abscess aspiration, abdominal paracentesis, therapeutic upper gastrointestinal endoscopy, abdominal surgery, endoscopic retrograde cholangiopancreatography and percutaneous transhepatic biliary drainage. After treatment, 25 patients (83.3%) showed a decreased median INR (from 1.6 to 1.3) (p < 0.001, Wilcoxon's signed-rank test). Five patients failed to show INR reduction. No new bleeding event related to the invasive procedures was observed. Conclusion PCC treatment is effective to control and prevent bleeding complications in patients with liver coagulopathy who undergo invasive procedures. PMID:27482190

  15. Fibrillation number based on wavelength and critical mass in patients who underwent radiofrequency catheter ablation for atrial fibrillation.

    PubMed

    Hwang, Minki; Park, Junbeum; Lee, Young-Seon; Park, Jae Hyung; Choi, Sung Hwan; Shim, Eun Bo; Pak, Hui-Nam

    2015-02-01

    The heart characteristic length, the inverse of conduction velocity (CV), and the inverse of the refractory period are known to determine vulnerability to cardiac fibrillation (fibrillation number, FibN) in in silico or ex vivo models. The purpose of this study was to validate the accuracy of FibN through in silico atrial modeling and to evaluate its clinical application in patients with atrial fibrillation (AF) who had undergone radiofrequency catheter ablation. We compared the maintenance duration of AF at various FibNAF values using in silico bidomain atrial modeling. Among 60 patients (72% male, 54±13 years old, 82% with paroxysmal AF) who underwent circumferential pulmonary vein isolation (CPVI) for AF rhythm control, we examined the relationship between FibN AF and postprocedural AF inducibility or induction pacing cycle length (iPCL). Clinical FibNAF was calculated using left atrium (LA) dimension (echocardiogram), the inverse of CV, and the inverse of the atrial effective refractory periods measured at proximal and distal coronary sinus. In silico simulation found a positive correlation between AF maintenance duration and FibNAF ( R = 0.90, ). After clinical CPVI, FibNAF ( 0.296±0.038 versus 0.192±0.028, ) was significantly higher in patients with postprocedural AF inducibility ( n = 41) than in those without ( n = 19 ). Among 41 patients with postprocedural AF inducibility, FibNAF ( P = 0.935, ) had excellent correlations with induction pacing cycle length. FibNAF, based on LA mass and wavelength, correlates well with AF maintenance in computational modeling and clinical AF inducibility after CPVI. PMID:25343755

  16. Clinical outcomes of 114 patients who underwent γ-knife radiosurgery for medically refractory idiopathic trigeminal neuralgia.

    PubMed

    Li, Peng; Wang, Wei; Liu, Yi; Zhong, Qi; Mao, Boyong

    2012-01-01

    The optimal radiation dose and target of Gamma-knife radiosurgery (GKRS) for medically refractory idiopathic trigeminal neuralgia (TN) are contentious. We investigated the effects and trigeminal nerve deficits of GKRS using two isocenters to treat a great length of the trigeminal nerve. Between January 2005 and March 2010, 129 patients with idiopathic TN underwent GKRS at the West China Hospital of Sichuan University. A maximum central dose of 80-90 Gy was delivered to the trigeminal nerve root with two isocenters via a 4mm collimator helmet. One hundred and fourteen patients were followed-up periodically by telephone interview to determine the effects, trigeminal nerve deficits and time to the onset of pain relief. The mean follow-up duration was 29.6 months. One hundred and nine patients had complete or partial pain relief and the treatment failed in five patients. Nine patients experienced a recurrence after a mean time of 12.7 months, following an initial interval of pain relief. There were no significant differences between patients with different grades of pain relief with respect to central doses. The mean time to the onset of pain relief was 3.6 weeks. The time to the onset of complete pain relief was significantly shorter than that for partial pain relief. Forty-nine patients reported mild-to-moderate facial numbness and one patient experienced paroxysmal temporalis muscle spasms two weeks after the treatment. GKRS treatment for medically refractory idiopathic TN with two isocenters resulted in an initial pain improvement in 95.6% of patients. The early response to the treatment might suggest a good outcome but, given the high incidence of nerve deficits, GKRS for TN with two isocenters is not recommended as a routine treatment protocol. PMID:22154202

  17. Association between Seminal Vesicle Invasion and Prostate Cancer Detection Location after Transrectal Systemic Biopsy among Men Who Underwent Radical Prostatectomy

    PubMed Central

    Lee, Young Ik; Lee, Hak Min; Jo, Jung Ki; Lee, Sangchul; Hong, Sung Kyu; Byun, Seok-Soo; Lee, Sang Eun; Oh, Jong Jin

    2016-01-01

    Background Our hypothesis is that the location of the seminal vesicles near the base of the prostate, the more positive cores are detected in the base, the greater the risk of seminal vesicle invasion. Therefore we investigate the clinical outcomes of base dominant prostate cancer (BDPC) in transrectal ultrasound (TRUS) -guided biopsies compared with anteromiddle dominant prostate cancer (AMPC). Methods From November 2003 to June 2014, a total of 990 intermediate and high risk prostate cancer (PCa) patients who underwent radical prostatectomy (RP) were enrolled and stratified into two groups according to proportion of positive cores–BDPC group had ≥ 33.3% ratio of positive cores from the prostate base among all positive cores and AMPC group < 33.3% in systemic biopsy. Between two groups, we compared the rate of pathologic outcomes and biochemical recurrence (BCR). We performed multivariate logistic regression model to confirm the significance of BDPC to seminal vesicle invasion (SVI) and Cox proportional hazard analysis to BCR. Results Among these 990 PCa patients, the 487 patients in BDPC group had more advanced clinical stage (p<0.001), a higher biopsy GS (p = 0.002), and a higher rate of extracapsular extension (ECE), SVI and BCR (all p<0.001) than AMPC group. The patients in BDPC group had poor BCR free survival rate via Kaplan-meier analysis (p<0.001). The ratio of the base positive cores was a significant predictor to SVI in multivariate analysis (p < 0.001) and significant predictor of BCR in multivariate Cox proportional analysis (hazard ratio: 1.466, p = 0.004). Conclusions BDPC in TRUS-guided prostate biopsies was significantly associated with SVI and BCR after adjusting for other clinical factors. Therefore, BDPC should be considered to be a more aggressive tumor despite an otherwise similar cancer profile. PMID:26848747

  18. The impact of cranioplasty on cerebral blood flow and its correlation with clinical outcome in patients underwent decompressive craniectomy

    PubMed Central

    Mah, Jon Kooi; Kass, Rosman Azmin

    2016-01-01

    Context: Decompressive craniectomy is commonly use as the treatment for medically refractory intracranial hypertension. Unexpected improvement in patient's neurological status has been observed among patients that underwent cranioplasty. Restoration of cerebral blood flow (CBF) hemodynamics is one of the contributing factors. This study was conducted to determine the impact of cranioplasty on CBF and its correlation with clinical outcome. Aims: This study was done to evaluate the effect of cranioplasty on CBF with computed tomography perfusion (CTP). It also aimed to determine the correlation between postcranioplasty CBF and clinical outcome. Settings and Design: Prospective observational study. Subjects and Methods: All patients had CTP done to determine precranioplasty CBF. CTP was repeated at 6 weeks postcranioplasty and clinical assessment at 6 and 24 weeks postcranioplasty. Statistical Analysis Used: Data analysis was done using Statistical Package for Social Sciences version 12.0.1. Results: The median value of the ipsilateral CBF was 48.87 and 61.10 ml/min/100 g at precranioplasty and 6 weeks postcranioplasty (P < 0.001). Contralateral CBF also showed improvement from 60.55 to 71.84 ml/min/100 g (P < 0.001). Median value for mini mental state examination showed a significant difference with value of 22, 25, and 25.5 at precranioplasty, 6 and 24 weeks postcranioplasty (P = 0.001 and P < 0.001). Median value for frontal assessment battery was 12, 14.5, and 15 (P = 0.002 and P = 0.001). Conclusions: Cranioplasty can remarkably improve cortical perfusion for both ipsilateral and contralateral hemisphere. Though we are unable to establish strong correlation, between CBF and clinical outcome, cranioplasty was observed to have a therapeutic role in terms of clinical outcome improvement. PMID:26889273

  19. De Garengeot's hernia in an 82-year-old man: a case report and clinical significance.

    PubMed

    Leite, Túlio F; Chagas, Carlos A A; Pires, Lucas A S; Cisne, Rafael; Babinski, Márcio A

    2016-01-01

    The presence of the appendix within a femoral hernia (FH) sac is known as Garengeot's hernia (GH). We report on current study a rare case of an elderly man with a combined inguinal and Garengeot's hernia and discuss the clinical aspects. An 82-year-old man clinically stable, presented history of pain at the right inguinal region for over a week, without vomit, nausea, fever or any alteration of intestinal or urinary eliminations. Clinical examination revealed a FH and the ultrasonography confirmed the hernia sac. During the surgery, the appendix was recognized within the sac, and then, the patient underwent appendectomy and hernia repair. In conclusion, the presence of the vermiform appendix in a FH sac is rare, thus, requiring knowledge of the surgeon regarding this clinical entity. Prompt diagnosis and appropriate surgical treatment is the key to avoid complications. PMID:27381019

  20. Analysis of subsequent surgery rates among endometriosis patients who underwent surgery with and without concomitant leuprolide acetate therapy.

    PubMed

    Soliman, Ahmed M; Bonafede, Machaon; Farr, Amanda M; Castelli-Haley, Jane; Winkel, Craig

    2016-06-01

    Objective To compare subsequent endometriosis-related surgery following initial laparoscopy among women treated with leuprolide acetate (LA) or other endometriosis therapies versus women who received no pharmacotherapy. Research design and methods This retrospective cohort analysis utilized MarketScan Commercial claims data. Women with endometriosis aged 18-49 who underwent laparoscopy between 1 January 2005 and 31 December 2011 were identified using diagnosis and procedures codes and were categorized into four cohorts based on claims within 90 days of laparoscopy: surgery plus adherent LA, surgery plus non-adherent LA, surgery plus other therapy, and surgery alone. Patients with proportion of days covered ≥0.80 in the 6 months after laparoscopy were considered adherent to LA. Main outcome measures Subsequent endometriosis-related surgery (laparoscopy, laparotomy or other excision/ablation/fulguration of endometriosis lesions, oophorectomy, or hysterectomy) was measured in the 6 and 12 months following initial laparoscopy. Risk of subsequent surgery was compared using multivariable Cox proportional hazards modeling. Results Most women were treated with surgery only (n = 9865); fewer were treated with LA (adherent: n = 202; non-adherent: n = 490) or other therapies (n = 230). The proportion of patients with subsequent surgery ranged from 2.0% to 10.0% during the 6 month follow-up (12 month: 9.7% to 13.5%). Adherent LA use was associated with significantly lower risk of surgery compared to surgery alone (hazard ratio [HR] = 0.31, p = 0.020) while use of other therapies was associated with significantly higher risk (HR = 1.51, p = 0.045) over the 6 month follow-up. There was no significant difference between the surgery plus non-adherent LA and surgery only cohort over 6 months (p = 0.247). The association between adherent LA and subsequent surgery was not significant over the 12 month follow-up. Conclusion Therapy with LA after

  1. Comparison of Standard Catheters Versus Radial Artery-Specific Catheter in Patients Who Underwent Coronary Angiography Through Transradial Access.

    PubMed

    Chen, On; Goel, Sunny; Acholonu, Michael; Kulbak, Guy; Verma, Shivani; Travlos, Efstratios; Casazza, Richard; Borgen, Elliot; Malik, Bilal; Friedman, Michael; Moskovits, Norbert; Frankel, Robert; Shani, Jacob; Ayzenberg, Sergey

    2016-08-01

    In this prospective, randomized controlled study, we aim to compare the performance outcomes of standard catheters with the radial artery-specific catheter. Over the past decade, transradial cardiac catheterization has gained widespread popularity because of its low complication rates compared with transfemoral access. Operators have the choice of using either standard catheters (used for both transfemoral and transradial approach, with need for separate catheter use for either right or left coronary artery engagement) or a dedicated radial artery catheter, which is specifically designed to engage both coronary arteries through radial artery access. A total of 110 consecutive patients who underwent coronary angiography at our institution from March 2015 to April 2015 were prospectively randomized to either radial artery-specific Tiger catheter (5Fr; Terumo Interventional Systems, Somerset, New Jersey) versus standard Judkins left and right catheters (5Fr R4, L4; Cordis Corporation, Miami, Florida). The end points of the study included fluoroscopy time, dose-area product, contrast volume used, and total procedure time for the coronary angiography. A total of 57 patients (52%) were randomized to radial artery-specific catheter and 53 (48%) to the standard catheter. Tiger catheter was associated with significantly lower fluoroscopy time (184 ± 91 vs 238 ± 131 seconds, p = 0.015), which was statistically significant. Other outcome measures such as dose-area product (2,882.4 ± 1,471.2 vs 3,524.6 ± 2,111.7 Gy·cm(2), p = 0.07), total contrast volume (48.1 ± 16.1 vs 53.4 ± 18.5 ml, p = 0.114), and total procedure time (337 ± 382 vs 434 ± 137 seconds, p = 0.085) were also lower in single-catheter group, but it did not reach statistical significance. A total of 8 patients (14%) were crossed over from radial-specific catheter arm to standard catheter arm because of substandard image quality and difficulty in coronary engagement. Six patients had to be

  2. Coronary artery surgery in a man with achondroplasia: a case report

    PubMed Central

    2010-01-01

    Introduction Achondroplasia is a musculoskeletal disorder associated with short stature. Despite an estimated prevalence of 1:25,000 in the general population, there is little literature concerning the diagnostic and treatment challenges faced by doctors dealing with a heart operation on a patient with this condition. Case presentation We present the case of a 41-year-old Caucasian man of Greek ethnicity with achondroplasia, who underwent bypass heart surgery. Conclusions The surgery was successful and did not present particular difficulties, showing that heart surgery can be safely performed on people with achondroplasia. PMID:21034450

  3. CA-125–indicated asymptomatic relapse confers survival benefit to ovarian cancer patients who underwent secondary cytoreduction surgery

    PubMed Central

    2013-01-01

    Background There is no consensus regarding the management of ovarian cancer patients, who have shown complete clinical response (CCR) to primary therapy and have rising cancer antigen CA-125 levels but have no symptoms of recurrent disease. The present study aims to determine whether follow-up CA-125 levels can be used to identify the need for imaging studies and secondary cytoreductive surgery (CRS). Methods We identified 410 ovarian cancer patients treated at The University of Texas MD Anderson Cancer Center between 1984 and 2011. These patients had shown CCR to primary therapy. Follow-up was conducted based on the surveillance protocol of the MD Anderson Cancer Center. We used the Cox proportional hazards model and log-rank test to assess the associations between the follow-up CA-125 levels and secondary CRS and survival duration. Results The CA-125 level of 1.68 × nadir was defined as the indicator of recurrent disease (p < 0.001). The specificity and sensitivity of this criterion were 82.9% and 85.6%, respectively, and the median lead-time of the CA-125 biochemical progression prior to clinically-defined relapse was 31 days (ranging from 1 to 391 days). The median number of the negative imaging studies for the clinical relapse findings in patients with a CA-125 level of < 1.68 × nadir was 3 (ranging from 0 to 24 times). The increase of CA-125 level at relapse was an independent predictor of overall and progression free survival in patients who had shown CCR to primary therapy (p = 0.04 and 0.02 respectively). The overall and progression free survival durations in patients with a CA-125 level ≤ 1.68 × nadir at relapse (69.4 and 13.8 months) were longer than those with a CA-125 level > 1.68 × nadir at relapse (55.7 and 10.4 months; p = 0.04 and 0.01, respectively). The overall and progression free survival duration of patients with asymptomatic relapse and underwent a secondary CRS was longer than that of

  4. Nuclear power: key to man's extraterrestrial civilization

    SciTech Connect

    Angelo, J.A. Jr.; Buden, D.

    1982-01-01

    The start of the Third Millennium will be highlighted by the establishment of man's extraterrestrial civilization with three technical cornerstones leading to the off-planet expansion of the human resource base. These are (1) the availability of compact energy sources for power and propulsion, (2) the creation of permanent manned habitats in space, and (3) the ability to process materials anywhere in the Solar System. In the 1990s and beyond, nuclear reactors could represent the prime source of both space power and propulsion. The manned and unmanned space missions of tomorrow will demand first kilowatt and then megawatt levels of power. Various nuclear power plant technologies will be discussed, with emphasis on derivatives from the nuclear rocket technology.

  5. A manned Mars artificial gravity vehicle

    NASA Technical Reports Server (NTRS)

    Schultz, David N.; Rupp, Charles C.; Hajos, Gregory A.; Butler, John M., Jr.

    1988-01-01

    Data are presented on an artificial-gravity vehicle that is being designed for a manned Mars mission, using a 'split-mission' concept, in which an unmanned cargo vehicle is sent earlier and stored in a Mars orbit for a rendezvous with a manned vehicle about 1.5 years later. Special attention is given to the vehicle trajectory and configuration, the tether design, and the vehicle weight and launch requirements. It is shown that an artificial-G vehicle for a manned Mars missions is feasible technically and programmatically. Using an artificial-G vehicle instead of a zero-G vehicle for the piloted portion of a split mission provides physiological and human-factor-related benefits, does not eliminate requirements for zero-G countermeasures research (since zero-G is an abort mode), and could possibly reduce some life science activities. Diagrams are included.

  6. The Centauri project: Manned interstellar travel

    NASA Technical Reports Server (NTRS)

    Ciesla, Thomas M.

    1990-01-01

    The development of antimatter engines for spacecraft propulsion will allow man to expand to the nearest stellar neighbors such as the Alpha Centuri system. Compared to chemically powered rockets like the Apollo mission class which would take 50,000 years to reach the Centauri system, antimatter propulsion would reduce one way trip time to 30 years or less. The challenges encountered by manned interstellar travel are formidable. The spacecraft must be a combination of sublight speed transportation system and a traveling microplanet serving an expanding population. As the population expands from the initial 100 people to approximately 300, the terraformed asteroid, enclosed by a man-made shell will allow for expansion over its surface in the fashion of a small terrestrial town. All aspects of human life - birth; death; physical, emotional, and educational needs; and government and law must be met by the structure, systems, and institutions on-board.

  7. The Computerized Anatomical Man (CAM) model

    NASA Technical Reports Server (NTRS)

    Billings, M. P.; Yucker, W. R.

    1973-01-01

    A computerized anatomical man (CAM) model, representing the most detailed and anatomically correct geometrical model of the human body yet prepared, has been developed for use in analyzing radiation dose distribution in man. This model of a 50-percentile standing USAF man comprises some 1100 unique geometric surfaces and some 2450 solid regions. Internal body geometry such as organs, voids, bones, and bone marrow are explicitly modeled. A computer program called CAMERA has also been developed for performing analyses with the model. Such analyses include tracing rays through the CAM geometry, placing results on magnetic tape in various forms, collapsing areal density data from ray tracing information to areal density distributions, preparing cross section views, etc. Numerous computer drawn cross sections through the CAM model are presented.

  8. Radiation protection for manned space activities

    NASA Technical Reports Server (NTRS)

    Jordan, T. M.

    1983-01-01

    The Earth's natural radiation environment poses a hazard to manned space activities directly through biological effects and indirectly through effects on materials and electronics. The following standard practices are indicated that address: (1) environment models for all radiation species including uncertainties and temporal variations; (2) upper bound and nominal quality factors for biological radiation effects that include dose, dose rate, critical organ, and linear energy transfer variations; (3) particle transport and shielding methodology including system and man modeling and uncertainty analysis; (4) mission planning that includes active dosimetry, minimizes exposure during extravehicular activities, subjects every mission to a radiation review, and specifies operational procedures for forecasting, recognizing, and dealing with large solar flaes.

  9. [Man and animal from the ethical view

    PubMed

    Teutsch, Gotthard M.

    1997-01-01

    This review over the books, articles in Journals and newspapers in 1996 and 1997 reports about the development in the field of man-animal- and man-nature-relations. The review considers the following themes: development, trends and perspectives, philosophy, theology, eco-ethics, legal questions, animal experimentation, freedom of research, teaching and conscience, farm animals, hunting and fishing, zoo and circus, bio-technology, violence, killing, vegetarism and dignity of creatures. The review includes a bibliography with about 300 quatoations. PMID:11178503

  10. Use of IPsec by Manned Space Missions

    NASA Technical Reports Server (NTRS)

    Pajevski, Michael J.

    2009-01-01

    NASA's Constellation Program is developing its next generation manned space systems for missions to the International Space Station (ISS) and the Moon. The Program is embarking on a path towards standards based Internet Protocol (IP) networking for space systems communication. The IP based communications will be paired with industry standard security mechanisms such as Internet Protocol Security (IPsec) to ensure the integrity of information exchanges and prevent unauthorized release of sensitive information in-transit. IPsec has been tested in simulations on the ground and on at least one Earth orbiting satellite, but the technology is still unproven in manned space mission situations and significant obstacles remain.

  11. Environment for Man, The Next Fifty Years.

    ERIC Educational Resources Information Center

    Ewald, William R., Jr.

    This volume is the first of three publications emanating from the American Institute of Planners' nationwide campaign to encourage study and public education on "the future environment of a democracy." Experts in many areas scrutinize the psychological, physiological, and social needs of modern man in an attempt to discover the kind of environment…

  12. Physiknobelei Kann man die Lichtausbreitung sehen?

    NASA Astrophysics Data System (ADS)

    Schlichting, H.-Joachim

    2003-07-01

    Des Menschen Sinne sind trügerisch. Das wussten schon die Philosophen der Antike, denen physikalische Zusammenhänge noch fremd waren. Doch auch in der heutigen aufgeklärten Zeit ereignen sich noch Dinge, bei denen man seinen Augen nicht traut.

  13. Teaching Rousseau: Natural Man and Present Existence.

    ERIC Educational Resources Information Center

    Rice, Daryl H.

    1989-01-01

    Offers an interpretation of Jean-Jacques Rousseau's "Discourse on the Origin and Foundations of Inequality" and provides examples of classroom exercises designed to make Rousseau's ideas and writings accessible to undergraduates. Stresses Rousseau's philosophy on natural man, language, ethics, and society. Includes interpretive references to…

  14. Nomadism as a Man-Environment System

    ERIC Educational Resources Information Center

    Rapoport, Amos

    1978-01-01

    Concepts derived from general man-environment system (MES) models are applied to the specific problem of nomadic sedentarization. The analysis focuses on the manner in which residential mobility may function as a central element in nomadic cultures. (Author/MA)

  15. Man's Response to the Physical Environment.

    ERIC Educational Resources Information Center

    Kates, R.W., Ed.; Wohlwill, J.F., Ed.

    1966-01-01

    Architects, psychologists, geographers, and biologists discuss the impact of the physical environment on man, and his adaptation to it. Article titles are as follows--(1) Galloping Technology, A New Social Disease, (2) Stimulus and Symbol: The View from the Bridge, (3) The Physical Environment: A Problem for a Psychology of Stimulation, (4)…

  16. Chemistry in "The Ascent of Man."

    ERIC Educational Resources Information Center

    Hostettler, John D.; Brooks, Kenneth

    1980-01-01

    Describes "The Ascent of Man," a course emphasizing science and human values. Detailed are some chemical topics covered in the course, and how these topics are used in other traditional chemistry courses. Topics discussed include alchemy, the chemical revolution, steam engines, the Manhattan project, and several bioethical problems. (CS)

  17. The Man-in-the-Middle Defence

    NASA Astrophysics Data System (ADS)

    Anderson, Ross

    The man-in-the-middle defence is all about rehabilitating Charlie. For 20 years we’ve worried about this guy in the middle, Charlie, who’s forever intercalating himself into the communications between Alice and Bob, and people have been very judgemental about poor Charlie, saying that Charlie is a wicked person. Well, we’re not entirely convinced.

  18. Manned Mars mission and planetary quarantine considerations

    NASA Technical Reports Server (NTRS)

    Sharp, Joseph C.

    1986-01-01

    A short review of the history of planetary quarantine, the issues, and changes in official advisory groups' pronouncements are presented. Then a discussion of the current situation and some ideas on how best to address them are outlined. Both manned and unmanned or automatic missions are discussed and their advantages and impediments outlined.

  19. Aerobrakes For A Manned Mars Mission

    NASA Technical Reports Server (NTRS)

    Menees, G. P.

    1990-01-01

    Paper presents results of study of aerobraking in manned mission to Mars. Describes geometry and aerodynamic characteristics of aerobraked vehicle. Discusses computer program, WTRAJ, used to simulate trajectories near planets. Analyzes aerocapture processes for both Mars and Earth. Examines mass efficiency, or saving in propellant mass, afforded by aerobraking.

  20. Asphalt and risk of cancer in man.

    PubMed

    Chiazze, L; Watkins, D K; Amsel, J

    1991-08-01

    Epidemiological publications regarding the carcinogenic potential of asphalt (bitumen) are reviewed. In 1984 the International Agency for Research on Cancer (IARC) stated that there is "inadequate evidence that bitumens alone are carcinogenic to humans." They did, however, conclude that animal data provided sufficient evidence for the carcinogenicity of certain extracts of steam refined and air refined bitumens. In the absence of data on man, IARC considered it reasonable to regard chemicals with sufficient evidence of carcinogenicity in animals as if they presented a carcinogenic risk to man. Epidemiological data for man accumulated since the IARC report do not fulfil the criteria for showing a causal association between exposure to asphalt and development of cancer. The studies cited all suffer from a lack of data on exposure or potential confounders, which are necessary to establish whether or not such an association may or may not exist. In view of the evidence (or lack thereof) regarding asphalt today, an appropriate public health attitude suggests at least that action be taken to protect those working with asphalt by monitoring the workplace, taking whatever steps are possible to minimise exposures and to inform workers of potential hazards. At the same time, a need exists for well designed analytical epidemiological studies to determine whether a risk of cancer in man exists from exposure to asphalt. PMID:1878310

  1. Alternatives for Man and Environment, Revised Curriculum.

    ERIC Educational Resources Information Center

    Miami-Dade Junior Coll., FL.

    A one-year general education course entitled "Man and Environment" has been developed at Miami-Dade Junior College, Florida. Basic framework for the course was built on the premise that an interdisciplinary, module-structured course represents one of the better approaches to planning environmental education curriculum. Material for the course may…

  2. Man and Environment, Study Guide, Volume One.

    ERIC Educational Resources Information Center

    Miami-Dade Junior Coll., FL.

    Subject information, course instructions, and resource materials for a television course, "Man and Environment," are compiled in this student study guide. The interdisciplinary, modular course emphasizes the importance of such concerns as destruction of the environment and the declining quality of life while educating the public about the…

  3. Man's Search: English, Mythology. 5112.22.

    ERIC Educational Resources Information Center

    Gundersheimer, Lenore C.

    A course which is an exploration of man's eternal search to understand himself and his world through the study of the mythology of the world is presented. Performance objectives include: (1) Students will recognize the content of the myths studied; (2) Students will identify the specific characteristics of the civilization studied; (3) Students…

  4. Nipple leiomyoma in man: a case report.

    PubMed

    Marrazzo, A; Taormina, P; Noto, A; Cardinale, G; Casa, L; Lo Gerfo, D

    2004-04-01

    We describe a rare case of a man, 38 year old, with a nipple leiomyoma, and report the presentation as a small nodule of the areola spreading the nipple, the symptoms, the clinical signs, the treatment that includes a complete excision; free margins should be histologically established to prevent recurrence. PMID:15283404

  5. Man and His Environment. Octagon Lectures 1969.

    ERIC Educational Resources Information Center

    Appleyard, R. T., Ed.

    Utilizing the theme "Man and His Environment," the Octagon Lectures of 1969 were presented at the University of Western Australia, Nedlands, Western Australia. Problems arising from the imbalance between the ancient forces of nature and the new forces of human culture were dealt with by the lecturers. They revealed that the most important…

  6. Space station support of manned Mars missions

    NASA Technical Reports Server (NTRS)

    Holt, Alan C.

    1986-01-01

    The assembly of a manned Mars interplanetary spacecraft in low Earth orbit can be best accomplished with the support of the space station. Station payload requirements for microgravity environments of .001 g and pointing stability requirements of less than 1 arc second could mean that the spacecraft may have to be assembled at a station-keeping position about 100 meters or more away from the station. In addition to the assembly of large modules and connective structures, the manned Mars mission assembly tasks may include the connection of power, fluid, and data lines and the handling and activation of components for chemical or nuclear power and propulsion systems. These assembly tasks will require the use of advanced automation and robotics in addition to Orbital Maneuvering Vehicle and Extravehicular Activity (EVA) crew support. Advanced development programs for the space station, including on-orbit demonstrations, could also be used to support manned Mars mission technology objectives. Follow-on studies should be conducted to identify space station activities which could be enhanced or expanded in scope (without significant cost and schedule impact) to help resolve key technical and scientific questions relating to manned Mars missions.

  7. The World of Man: A Curriculum Guide.

    ERIC Educational Resources Information Center

    Peters, Richard O.

    This one semester, ecology-oriented, eleventh or twelfth grade elective course exposes students to the problems of environmental degradation and makes them aware of man's attempts to remedy crisis situations. The curriculum guide is divided into three major topics, each comprised of several subtopics which include content, objectives, and…

  8. Thermal protection systems manned spacecraft flight experience

    NASA Technical Reports Server (NTRS)

    Curry, Donald M.

    1992-01-01

    Since the first U.S. manned entry, Mercury (May 5, 1961), seventy-five manned entries have been made resulting in significant progress in the understanding and development of Thermal Protection Systems (TPS) for manned rated spacecraft. The TPS materials and systems installed on these spacecraft are compared. The first three vehicles (Mercury, Gemini, Apollo) used ablative (single-use) systems while the Space Shuttle Orbiter TPS is a multimission system. A TPS figure of merit, unit weight lb/sq ft, illustrates the advances in TPS material performance from Mercury (10.2 lb/sq ft) to the Space Shuttle (1.7 lb/sq ft). Significant advances have been made in the design, fabrication, and certification of TPS on manned entry vehicles (Mercury through Shuttle Orbiter). Shuttle experience has identified some key design and operational issues. State-of-the-art ceramic insulation materials developed in the 1970's for the Space Shuttle Orbiter have been used in the initial designs of aerobrakes. This TPS material experience has identified the need to develop a technology base from which a new class of higher temperature materials will emerge for advanced space transportation vehicles.

  9. Design of Man-Computer Dialogues.

    ERIC Educational Resources Information Center

    Martin, James

    An attempt is made to provide a comprehensive guide to design of the dialogues between man and computer that take place at computer terminals. Particular topics include problems with conventional alphanumeric dialogues, dialogues with sound and graphics, pyschological characteristics of computer terminal users, problems of designing dialogues for…

  10. University for Man Annual Report for 1981.

    ERIC Educational Resources Information Center

    Kansas State Univ., Manhattan. University for Man.

    The 1981 report describes current activities, publications and films, sources of financial support, and organizational overview of the University for Man (UFM), founded in 1967 in Manhattan, Kansas, on the concept of citizens learning from each other and involving themselves to affect their community. The organization is divided into three program…

  11. Odd-Man-Out and Intelligence.

    ERIC Educational Resources Information Center

    Diascro, Matthew N.; Brody, Nathan

    1994-01-01

    The relationship between odd-man-out reaction time tasks and intelligence was examined in 2 experiments involving 79 college students. The two experiments indicate that tasks that assess the ability to perceive relationships among stimuli rapidly are good measures of general intelligence. (SLD)

  12. Asher Brown Durand: "An Old Man's Reminiscences."

    ERIC Educational Resources Information Center

    Lind, Ted

    1988-01-01

    Uses Durand's "An Old Man's Reminiscences" to introduce students in grades 4-6 to the effective use of nostalgia and memories in artwork. Presents lesson objectives, instructional strategies, evaluation criteria, and background information about the artist and the painting. (GEA)

  13. "On Making Man Modern"--A Review.

    ERIC Educational Resources Information Center

    Rivera, William M.

    A. Inkeles' cross-cultural work is reviewed. Inkeles studied young factory workers in six developing countries (Argentina, Chile, India, Israel, Nigeria, and East Pakistan) to determine their "modernity" characteristics versus their "traditional" or rural orientations. The use of the "modern man" thesis in this study, that is, that the factory can…

  14. The Tree Man: Robert Mazibuko's Story.

    ERIC Educational Resources Information Center

    Bloch, Joanne, Ed.

    This book for beginning readers highlights Robert Mazibuko, the "Tree Man," who spent his life teaching people how to enrich the soil and plant vegetables and trees. Born in South Africa in 1904, he lived on a farm, learning to work with livestock, raise crops, and share with the community. In college, his professor of agriculture provided a…

  15. Impotency in Pinter's No Man's Land

    ERIC Educational Resources Information Center

    Post, Robert M.

    1977-01-01

    Contends that Pinter's play, No Man's Land, is about impotency as well as stasis and old age. Focuses on the allusions to sex which function both literally and figuratively and includes metaphorical ramifications of the mentally, emotionally, and spiritually barren. (MH)

  16. ONLINE MENDELIAN INHERITANCE IN MAN (OMIM)

    EPA Science Inventory

    Welcome to OMIM(TM), Online Mendelian Inheritance in Man. This database is a catalog of human genes and genetic disorders authored and edited by Dr. Victor McKusick and his colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Cent...

  17. A Mediagraphy Relating to the Black Man.

    ERIC Educational Resources Information Center

    Parker, James E., Comp.

    Media dealing with the Black man--his history, art, problems, and aspirations--are listed under 10 headings: (1) disc recordings, (2) filmstrips and multimedia kits, (3) microfilms, (4) motion pictures, (5) pictures, posters and charts, (6) reprints, (7) slides, (8) tape recordings, (9) telecourses (kinescopes and videotapes), and (10)…

  18. [A man with a crooked smile].

    PubMed

    Bechan, M A H Afzal; van Dortmont, Laura M C; Claes, J Franka H M

    2013-01-01

    A 51-year-old man had a paresis of the right side of the lower lip after carotic endarterectomy. The diagnosis was 'pressure neuropathy of the right ramus marginalis mandibulae' caused by the operation. This neuropathy is self limiting. PMID:24152368

  19. Genetic Engineering: The Modification of Man

    ERIC Educational Resources Information Center

    Sinsheimer, Robert L.

    1970-01-01

    Describes somatic and genetic manipulations of individual genotypes, using diabetes control as an example of the first mode that is potentially realizable be derepression or viral transduction of genes. Advocates the use of genetic engineering of the second mode to remove man from his biological limitations, but offers maxims to ensure the…

  20. Forests and Man. Environmental Education Curriculum. Revised.

    ERIC Educational Resources Information Center

    Topeka Public Schools, KS.

    This environmental education module focuses on forests and man, and contains a series of papers which deal with topics related to forest ecology and conservation. The module is designed around the four following ideas: (1) the kinds of plants and animals and the roles they have in the forest environment; (2) using concepts of food webs and energy…

  1. Asphalt and risk of cancer in man.

    PubMed Central

    Chiazze, L; Watkins, D K; Amsel, J

    1991-01-01

    Epidemiological publications regarding the carcinogenic potential of asphalt (bitumen) are reviewed. In 1984 the International Agency for Research on Cancer (IARC) stated that there is "inadequate evidence that bitumens alone are carcinogenic to humans." They did, however, conclude that animal data provided sufficient evidence for the carcinogenicity of certain extracts of steam refined and air refined bitumens. In the absence of data on man, IARC considered it reasonable to regard chemicals with sufficient evidence of carcinogenicity in animals as if they presented a carcinogenic risk to man. Epidemiological data for man accumulated since the IARC report do not fulfil the criteria for showing a causal association between exposure to asphalt and development of cancer. The studies cited all suffer from a lack of data on exposure or potential confounders, which are necessary to establish whether or not such an association may or may not exist. In view of the evidence (or lack thereof) regarding asphalt today, an appropriate public health attitude suggests at least that action be taken to protect those working with asphalt by monitoring the workplace, taking whatever steps are possible to minimise exposures and to inform workers of potential hazards. At the same time, a need exists for well designed analytical epidemiological studies to determine whether a risk of cancer in man exists from exposure to asphalt. PMID:1878310

  2. How was the Turin Shroud Man crucified?

    PubMed

    Bevilacqua, M; Fanti, G; D'Arienzo, M; Porzionato, A; Macchi, V; De Caro, R

    2014-12-01

    As the literature is not exhaustive with reference to the way the Turin Shroud (TS) Man was crucified, and it is not easy to draw significant information from only a "photograph" of a man on a linen sheet, this study tries to add some detail on this issue based on both image processing of high resolution photos of the TS and on experimental tests on arms and legs of human cadavers. With regard to the TS Man hands, a first hypothesis states that the left hand of the TS Man was nailed twice at two different anatomical sites: the midcarpal joint medially to the pisiform between the lunate/pyramidal and capitate/uncinate bones (Destot's space) and the radiocarpal joint between the radio, lunate and scaphoid; also the right hand would have been nailed twice. A second hypothesis, preferred by the authors, states that the hands were nailed only once in the Destot's space with partial lesion of the ulnar nerve and flexion of the metacarpophalangeal joint of the thumbs. With regard to the TS Man feet, the imprint of the sole of the right foot leads to the conclusion that TS Man suffered a dislocation at the ankle just before the nailing. The entrance hole of the nail on the right foot is a few inches from the ankle, and excludes a double nailing. The nail has been driven between the tarsal bones. The TS Man suffered the following tortures during crucifixion: a very serious and widespread causalgia due to total paralysis of the upper right limb (paradoxical causalgia); a nailing of the left wrist with damage to the ulnar nerve; a similar nailing of the right wrist; and a nailing to both feet using one only nail that injured the plantaris medialis nerves. The respiratory limitation was probably not sufficient to cause death by asphyxiation. Also considering the hypovolemia produced by scourging and the many other tortures detectable on the TS, the principal cause of death can be attributed to a myocardial infarction. PMID:25457335

  3. Manned flight and planetary scientific exploration.

    NASA Astrophysics Data System (ADS)

    Muller, Christian; Moreau, Didier

    2014-05-01

    Human explorers had a fundamental role in the success of the APOLLO moon programme, they were at the same time the indispensable pilots, scientific operators and on the last missions lead scientists. Since, man did not either return to the moon or land on Mars but manned operation centres on the earth are now conducting extensive telescience on both celestial bodies. Manned flights to moon, Mars and asteroids are however still on the agenda and even if the main drive of these projects is outside science, it is to the planetary scientists to both prepare the data bases necessary for these flights and to ensure that the scientific advantage of conducting research in real time and in situ is exploited to the maximum. The current manned flight programme in Europe concentrates on the use of the International Space Station, the scientific activities can be roughly divided between the pressurized payloads and the external payloads. Technology developments occur also in parallel and prepare new exploration techniques. The current planning leads to exploitation up to 2020 but the space agencies study further extensions, the date of 2028 having already been considered. The relation of these programmes to future manned planetary exploration will be described both from the science and development point of view. The complementary role of astronauts and ground operation centres will be described on the basis of the current experience of operation centres managing the International Space Station. Finally, the NASA ORION project of exploration in the solar system will be described with emphasis on its current European participations. The science opportunities presented by independent ventures as Inspiration Mars or Mars One will be presented.

  4. Romboutsia timonensis, a new species isolated from human gut.

    PubMed

    Ricaboni, D; Mailhe, M; Khelaifia, S; Raoult, D; Million, M

    2016-07-01

    The exploration of the human microbiome was recently revolutionized by microbial culturomics and taxonogenomics. Thanks to this approach, we report here the main characteristics of Romboutsia timonensis strain Marseille-P326, a new bacterium isolated from the right human colon by colonoscopy in a 63-year-old French man with severe anaemia with melaena. PMID:27200178

  5. Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient.

    PubMed

    Chan, Hung-Yu; Lee, Kuan-I

    2015-03-01

    Alcohol withdrawal syndrome is a commonly seen problem in psychiatric practice. Alcohol withdrawal delirium is associated with significant morbidity and mortality. Withdrawal symptoms usually include tremulousness, psychotic and perceptual symptoms, seizures, and consciousness disturbance. Herein, we report a case involving a 63-year-old man who had alcohol withdrawal delirium that was manifested mainly by manic symptoms. PMID:25515164

  6. Last Breath: Art Therapy with a Lung Cancer Patient Facing Imminent Death

    ERIC Educational Resources Information Center

    Furman, Lisa R.

    2011-01-01

    Art therapy can be an effective way to focus on end of life issues with cancer patients facing imminent death. This viewpoint discusses ethical challenges in the treatment of a 63-year-old man with terminal lung cancer who was participating in short-term individual art therapy. Difficult issues that often surface in the final days of life may…

  7. Baylisascaris procyonis–Associated Meningoencephalitis in a Previously Healthy Adult, California, USA

    PubMed Central

    Reid, Michael J.; Halabi, Cathra; Wietek, Natalie; LaRiviere, Alejandro; Shah, Maulik; Wilson, Michael R.; Chin-Hong, Peter; Douglas, Vanja; Kazacos, Kevin R.; Babik, Jennifer M.

    2016-01-01

    After severe neurocognitive decline developed in an otherwise healthy 63-year-old man, brain magnetic resonance imaging showed eosinophilic meningoencephalitis and enhancing lesions. The patient tested positive for antibodies to Baylisascaris spp. roundworms, was treated with albendazole and dexamethasone, and showed improvement after 3 months. Baylisascariasis should be considered for all patients with eosinophilic meningitis. PMID:27434260

  8. Baylisascaris procyonis-Associated Meningoencephalitis in a Previously Healthy Adult, California, USA.

    PubMed

    Langelier, Charles; Reid, Michael J; Halabi, Cathra; Wietek, Natalie; LaRiviere, Alejandro; Shah, Maulik; Wilson, Michael R; Chin-Hong, Peter; Douglas, Vanja; Kazacos, Kevin R; Babik, Jennifer M

    2016-08-01

    After severe neurocognitive decline developed in an otherwise healthy 63-year-old man, brain magnetic resonance imaging showed eosinophilic meningoencephalitis and enhancing lesions. The patient tested positive for antibodies to Baylisascaris spp. roundworms, was treated with albendazole and dexamethasone, and showed improvement after 3 months. Baylisascariasis should be considered for all patients with eosinophilic meningitis. PMID:27434260

  9. CluMan - Cluster management toolsuit

    NASA Astrophysics Data System (ADS)

    Šiket, Miroslav; Babik, Marián; Lopienski, Sebastian; Borba Manana, Filipe David

    2010-04-01

    LHC computing requirements are such that the number of CPU and storage nodes, and the complexity of the services to be managed are bringing new challenges. Operations like checking configuration consistency, executing actions on nodes, moving them between clusters etc. are very frequent. These scaling challenges are the basis for CluMan, a new cluster management tool being designed and developed at CERN. High-density displays such as heat maps, grids or color maps are more and more commonly used in various applications like data visualization or monitoring systems. They allow humans to see, interpret and understand complex and detailed information at a glance. We propose to present the ideas behind the CluMan project, and to show how high density displays are used to help service managers to understand, manage and control the state and behavior of their clusters.

  10. Design and Construction of Manned Lunar Base

    NASA Astrophysics Data System (ADS)

    Li, Zhijie

    2016-07-01

    Building manned lunar base is one of the core aims of human lunar exploration project, which is also an important way to carry out the exploitation and utilization of lunar in situ resources. The most important part of manned lunar base is the design and construction of living habitation and many factors should be considered including science objective and site selection. Through investigating and research, the scientific goals of manned lunar base should be status and characteristics ascertainment of lunar available in situ resources, then developing necessary scientific experiments and utilization of lunar in situ resources by using special environment conditions of lunar surface. The site selection strategy of manned lunar base should rely on scientific goals according to special lunar surface environment and engineering capacity constraints, meanwhile, consulting the landing sites of foreign unmanned and manned lunar exploration, and choosing different typical regions of lunar surface and analyzing the landform and physiognomy, reachability, thermal environment, sunlight condition, micro meteoroids protection and utilization of in situ resources, after these steps, a logical lunar living habitation site should be confirmed. This paper brings out and compares three kinds of configurations with fabricating processes of manned lunar base, including rigid module, flexible and construction module manned lunar base. 1.The rigid habitation module is usually made by metal materials. The design and fabrication may consult the experience of space station, hence with mature technique. Because this configuration cannot be folded or deployed, which not only afford limit working and living room for astronauts, but also needs repetitious cargo transit between earth and moon for lunar base extending. 2. The flexible module habitation can be folded in fairing while launching. When deploying on moon, the configuration can be inflatable or mechanically-deployed, which means under

  11. Manning's roughness coefficient for Illinois streams

    USGS Publications Warehouse

    Soong, David T.; Prater, Crystal D.; Halfar, Teresa M.; Wobig, Loren A.

    2012-01-01

    Manning's roughness coefficients for 43 natural and constructed streams in Illinois are reported and displayed on a U.S. Geological Survey Web site. At a majority of the sites, discharge and stage were measured, and corresponding Manning's coefficients—the n-values—were determined at more than one river discharge. The n-values discussed in this report are computed from data representing the stream reach studied and, therefore, are reachwise values. Presentation of the resulting n-values takes a visual-comparison approach similar to the previously published Barnes report (1967), in which photographs of channel conditions, description of the site, and the resulting n-values are organized for each site. The Web site where the data can be accessed and are displayed is at URL http://il.water.usgs.gov/proj/nvalues/.

  12. Terrapin technologies manned Mars mission proposal

    NASA Technical Reports Server (NTRS)

    Amato, Michael; Bryant, Heather; Coleman, Rodney; Compy, Chris; Crouse, Patrick; Crunkleton, Joe; Hurtado, Edgar; Iverson, Eirik; Kamosa, Mike; Kraft, Lauri (Editor)

    1990-01-01

    A Manned Mars Mission (M3) design study is proposed. The purpose of M3 is to transport 10 personnel and a habitat with all required support systems and supplies from low Earth orbit (LEO) to the surface of Mars and, after an eight-man surface expedition of 3 months, to return the personnel safely to LEO. The proposed hardware design is based on systems and components of demonstrated high capability and reliability. The mission design builds on past mission experience, but incorporates innovative design approaches to achieve mission priorities. Those priorities, in decreasing order of importance, are safety, reliability, minimum personnel transfer time, minimum weight, and minimum cost. The design demonstrates the feasibility and flexibility of a Waverider transfer module.

  13. Manned versus unmanned - The implications to NASP

    NASA Technical Reports Server (NTRS)

    Wierzbanowski, Theodore; Kasten, Terry D.

    1990-01-01

    The assessment of unmanned approaches to experimental aerospace vehicles in general and to the NASP program in particular is summarized. Technical requirements for NASP demonstration are presented and unmanned options for satisfying requirements are discussed. The X-30 sensitivities to technical requirements are described. A correlation of the NASP program to prior flight test programs, both manned and unmanned, is also presented. It is noted that subscale vehicles may reduce risk by as much as 18 percent for approximately $200 M. It is concluded that half-scale vehicles may reduce program risk by 60 percent, while reducing X-30 costs by 40 percent. Also, an unmanned X-30 will probably cost more than a manned X-30 due to costs associated with additional software development and ground support systems costs.

  14. One man electrochemical air revitalization system

    NASA Technical Reports Server (NTRS)

    Huddleston, J. C.; Aylward, J. R.

    1975-01-01

    An integrated water vapor electrolysis (WVE) hydrogen depolarized CO2 concentrator (HDC) system sized for one man support over a wide range of inlet air conditions was designed, fabricated, and tested. Data obtained during 110 days of testing verified that this system can provide the necessary oxygen, CO2 removal, and partial humidity control to support one man (without exceeding a cabin partial pressure of 3.0 mmHg for CO2 and while maintaining a 20% oxygen level), when operated at a WVE current of 50 amperes and an HDC current of 18 amperes. An evaluation to determine the physical properties of tetramethylammonium bicarbonate (TMAC) and hydroxide was made. This provides the necessary electrolyte information for designing an HDC cell using TMAC.

  15. Man-machine collaboration using facial expressions

    NASA Astrophysics Data System (ADS)

    Dai, Ying; Katahera, S.; Cai, D.

    2002-09-01

    For realizing the flexible man-machine collaboration, understanding of facial expressions and gestures is not negligible. In our method, we proposed a hierarchical recognition approach, for the understanding of human emotions. According to this method, the facial AFs (action features) were firstly extracted and recognized by using histograms of optical flow. Then, based on the facial AFs, facial expressions were classified into two calsses, one of which presents the positive emotions, and the other of which does the negative ones. Accordingly, the facial expressions belonged to the positive class, or the ones belonged to the negative class, were classified into more complex emotions, which were revealed by the corresponding facial expressions. Finally, the system architecture how to coordinate in recognizing facil action features and facial expressions for man-machine collaboration was proposed.

  16. Landing Energy Dissipation for Manned Reentry Vehicles

    NASA Technical Reports Server (NTRS)

    1960-01-01

    Landing Energy Dissipation for Manned Reentry Vehicles. The film shows experimental investigations to determine the landing-energy-dissipation characteristics for several types of landing gear for manned reentry vehicles. The landing vehicles are considered in two categories: those having essentially vertical-descent paths, the parachute-supported vehicles, and those having essentially horizontal paths, the lifting vehicles. The energy-dissipation devices include crushable materials such as foamed plastics and honeycomb for internal application in couch-support systems, yielding metal elements as part of the structure of capsules or as alternates for oleos in landing-gear struts, inflatable bags, braking rockets, and shaped surfaces for water impact. [Entire movie available on DVD from CASI as Doc ID 20070030945. Contact help@sti.nasa.gov

  17. MOOSE: Manned On-Orbit Servicing Equipment

    NASA Technical Reports Server (NTRS)

    Budinoff, J. (Editor); Leontsinis, N. (Editor); Lane, J. (Editor); Singh, R. (Editor); Angelone, K.; Boswell, C.; Chamberlain, I.; Concha, M.; Corrodo, M.; Custodio, O.

    1993-01-01

    The ability to service satellites has thus far been limited to low earth orbit platforms within reach of the Space Shuttle. Other orbits, such as geosynchronous orbits containing high-value spacecraft have not been attainable by a servicing vehicle. The useful life of a satellite can be extended by replacing spent propellant and damaged orbital replacement units, forestalling the need for eventual replacement. This growing need for satellite on-orbits servicing can be met by the Manned On-Orbit Servicing Equipment (MOOSE). Missions requiring orbit transfer capability, precision manipulation and maneuvering, and man-in-the-loop control can be accomplished using MOOSE. MOOSE is a flexible, reusable, single operator, aerobraking spacecraft designed to refuel, repair, and service orbiting spacecraft. MOOSE will be deployed from Space Station Freedom, (SSF), where it will be stored, resupplied, and refurbished.

  18. Neural networks in support of manned space

    NASA Technical Reports Server (NTRS)

    Werbos, Paul J.

    1989-01-01

    Many lobbyists in Washington have argued that artificial intelligence (AI) is an alternative to manned space activity. In actuality, this is the opposite of the truth, especially as regards artificial neural networks (ANNs), that form of AI which has the greatest hope of mimicking human abilities in learning, ability to interface with sensors and actuators, flexibility and balanced judgement. ANNs and their relation to expert systems (the more traditional form of AI), and the limitations of both technologies are briefly reviewed. A Few highlights of recent work on ANNs, including an NSF-sponsored workshop on ANNs for control applications are given. Current thinking on ANNs for use in certain key areas (the National Aerospace Plane, teleoperation, the control of large structures, fault diagnostics, and docking) which may be crucial to the long term future of man in space is discussed.

  19. A Study for Mars Manned Exploration

    NASA Technical Reports Server (NTRS)

    Dorney, Daniel J.; Scimemi, Sam

    2012-01-01

    Over the last five decades there have been numerous studies devoted to developing, launching and conducting a manned mission to Mars by both Russian and U.S. organizations. These studies have proposed various crew sizes, mission length, propulsion systems, habitation modules, and scientific goals. As a first step towards establishing an international partnership approach to a Mars mission, the most recent Russian concepts are explored and then compared to NASA's latest Mars reference mission.

  20. Possible Scenarios for Mars Manned Exploration

    NASA Technical Reports Server (NTRS)

    Dorney, Daniel J.; Schumacher, Daniel M.

    2012-01-01

    Over the last five decades there have been numerous studies devoted to developing, launching and conducting a manned mission to Mars by both Russian and U.S. organizations. These studies have proposed various crew sizes, mission length, propulsion systems, habitation modules, and scientific goals. As a first step towards establishing an international partnership approach to a Mars mission, the most recent Russian concepts are explored and then compared to NASA's current Mars reference mission.

  1. The Manned Spacecraft Center and medical technology

    NASA Technical Reports Server (NTRS)

    Johnston, R. S.; Pool, S. L.

    1974-01-01

    A number of medically oriented research and hardware development programs in support of manned space flights have been sponsored by NASA. Blood pressure measuring systems for use in spacecraft are considered. In some cases, complete new bioinstrumentation systems were necessary to accomplish a specific physiological study. Plans for medical research during the Skylab program are discussed along with general questions regarding space-borne health service systems and details concerning the Health Services Support Control Center.

  2. Ant-Man and the quantum realm

    NASA Astrophysics Data System (ADS)

    Michalakis, Spiros

    2015-11-01

    I was in Los Angeles airport, stuffing French fries into my mouth and waiting for a flight to Charlotte, North Carolina, when my phone buzzed. The e-mail was from the Science and Entertainment Exchange, a non-profit organization working to elevate the level of science in the movies, and it told me to report to Atlanta to consult on a new superhero movie: Ant-Man.

  3. L1 libration point manned space habitat

    NASA Technical Reports Server (NTRS)

    Luttges, Marvin; Johnson, Steve; Banks, Gary; Johnson, Richard; Meyer, Christian; Pepin, Scott; Macelroy, Robert

    1989-01-01

    Second generation stations or Manned Space Habitats (MSHs) are discussed for an Earth-Moon libration point and in lunar orbit. The conceptual design of such a station is outlined. Systems and subsystems described reflect anticipation of moderate technology growth. The evolution of the L1 environments is discussed, several selected subsystems are outlined, and how the L1 MSH will complete some of its activities is described.

  4. Sleep monitoring - The second manned Skylab mission

    NASA Technical Reports Server (NTRS)

    Frost, J. D., Jr.; Shumate, W. H.; Booher, C. R.; Salamy, J. G.

    1976-01-01

    Sleep patterns were monitored in one subject aboard each of the manned Skylab missions. In all three subjects stage 3 sleep increased during the flight and consistently decreased postflight. Stage REM was elevated, and REM latency decreased in the late postflight period. The number of awakenings remained the same or decreased during flight. No changes were observed which could be expected to adversely affect performance capability.

  5. First multiphoton tomography of brain in man

    NASA Astrophysics Data System (ADS)

    König, Karsten; Kantelhardt, Sven R.; Kalasauskas, Darius; Kim, Ella; Giese, Alf

    2016-03-01

    We report on the first two-photon in vivo brain tissue imaging study in man. High resolution in vivo histology by multiphoton tomography (MPT) including two-photon FLIM was performed in the operation theatre during neurosurgery to evaluate the feasibility to detect label-free tumor borders with subcellular resolution. This feasibility study demonstrates, that MPT has the potential to identify tumor borders on a cellular level in nearly real-time.

  6. The Man-in-the-Middle Defence

    NASA Astrophysics Data System (ADS)

    Anderson, Ross; Bond, Mike

    Eliminating middlemen from security protocols helps less than one would think. EMV electronic payments, for example, can be made fairer by adding an electronic attorney - a middleman which mediates access to a customer’s card. We compare middlemen in crypto protocols and APIs with those in the real world, and show that a man-in-the-middle defence is helpful in many circumstances. We suggest that the middleman has been unfairly demonised.

  7. Aerobraking systems for manned Mars missions

    NASA Technical Reports Server (NTRS)

    Eldred, Charles H.

    1992-01-01

    This paper presents a synopsis of aerobraking uses, benefits, performance requirements, design issues, and technology requirements for manned Mars missions. Aerobraking can provide significant advantages in several key mission functions: Mars orbit capture, Mars entry from orbit, and earth orbit capture or direct entry. The resulting range of aerobraking performance requirements are described. Study results show that none of the aerobrake unique concerns are show stoppers but are issues having reasonable design solutions and operational impacts.

  8. Movable Lander for Manned Mars Mission

    NASA Technical Reports Server (NTRS)

    2001-01-01

    In the second half of the workshop, participants split into three groups to develop a concensus on the following questions: (1) What are the current space drive resources and issues? (2) What are the future space drive technology needs and issues? and (3) Should we hold regular workshops on space mechanisms and space drives? The three groups considered these questions from the perspective of researchers working in (1) manned spacecraft; (2) unmanned spacecraft; and (3) planetary surface exploration vehicles.

  9. Manned Mars missions: A working group report

    NASA Technical Reports Server (NTRS)

    Duke, Michael B. (Editor); Keaton, Paul W. (Editor)

    1986-01-01

    The discussions of the Working Group (based in large part on working papers, which will shortly be published separately) are summarized. These papers cover a broad range of subjects which need to be addressed in the formulation of such a formidable enterprise as a manned Mars program. Science objective and operations; Mars surface infrastructure and activities; mission and system concepts and configurations; life sciences; impacts on the space infrastructure; and costs, schedules, and organizations are addressed.

  10. Man-machine interface requirements - advanced technology

    NASA Technical Reports Server (NTRS)

    Remington, R. W.; Wiener, E. L.

    1984-01-01

    Research issues and areas are identified where increased understanding of the human operator and the interaction between the operator and the avionics could lead to improvements in the performance of current and proposed helicopters. Both current and advanced helicopter systems and avionics are considered. Areas critical to man-machine interface requirements include: (1) artificial intelligence; (2) visual displays; (3) voice technology; (4) cockpit integration; and (5) pilot work loads and performance.

  11. Bobby Fong: Man on a Mission

    ERIC Educational Resources Information Center

    Fong, Colin

    2014-01-01

    Bobby Fong, was president of Ursinus College until his death in September 2014 and is the only person to have served twice as chair of the AAC&U Board of Directors. In this article, his son Collin presents remarks made at the memorial service for his father. Collin describes his father as a man with a mission, and that mission was to make the…

  12. Kimberlites of the Man craton, West Africa

    NASA Astrophysics Data System (ADS)

    Skinner, E. M. W.; Apter, D. B.; Morelli, C.; Smithson, N. K.

    2004-09-01

    The Man craton in West Africa is an Archaean craton formerly joined to the Guyana craton (South America) that was rifted apart in the Mesozoic. Kimberlites of the Man craton include three Jurassic-aged clusters in Guinea, two Jurassic-aged clusters in Sierra Leone, and in Liberia two clusters of unknown age and one Neoproterozoic cluster recently dated at ˜800 Ma. All of the kimberlites irrespective of age occur as small pipes and prolific dykes. Some of the Banankoro cluster pipes in Guinea, the Koidu pipes in Sierra Leone and small pipes in the Weasua cluster in Liberia contain hypabyssal-facies kimberlite and remnants of the so-called transitional-facies and diatreme-facies kimberlite. Most of the Man craton kimberlites are mineralogically classified as phlogopite kimberlites, although potassium contents are relatively low. They are chemically similar to mica-poor Group 1A Southern African examples. The Jurassic kimberlites are considered to represent one province of kimberlites that track from older bodies in Guinea (Droujba 153 Ma) to progressively younger kimberlites in Sierra Leone (Koidu, 146 Ma and Tongo, 140 Ma). The scarcity of diatreme-facies kimberlites relative to hypabyssal-facies kimberlites and the presence of the so-called transitional-facies indicate that the pipes have been eroded down to the interface between the root and diatreme zones. From this observation, it is concluded that extensive erosion (1-2 km) has occurred since the Jurassic. In addition to erosion, the presence of abundant early crystallizing phlogopite is considered to have had an effect on the relatively small sizes of the Man craton kimberlites.

  13. Manned Mars missions using propellant from space

    SciTech Connect

    Zuppero, A.C.; Olson, T.S. ); Redd, L.R. )

    1993-01-10

    .A recent discovery (8/14/92) of a near-earth object containing materials potentially useful for space activities could perhaps change the entire way humans access and operate in space. A near-Earth object ([number sign]4015, 1979 VA, comet Wilson-Harrington) contains water ice that could be used for space propulsion. In addition, this type of object may contain structural and lifesustaining materials (complex hydrocarbons, ammonia and/or bound nitrogen compounds) for space structures, manned planetary bases, or planetary surface terraforming. The retrieval and utilization of rocket propellant from near-Earth objects, for manned Mars missions in particular, has been investigated and the benefits of this scenario to over performing a Mars mission with terrestrial propellants have been documented. The results show water extracted from these objects and retrieved to Earth orbit for use in going to Mars may actually enable manned Mars exploration by reducing the number of Heavy Lift Launch Vehicle (HLLV) flights or eliminating the need for HLLV's altogether. The mission can perhaps be supported with existing launch vehicles and not required heavy lift capability. Also, the development of a nuclear thermal rocket for this alternate approach may be simplified substantially by reducing the operating temperature required.

  14. Manned testing in a simulated space environment

    NASA Astrophysics Data System (ADS)

    Fender, Donna L.

    1992-11-01

    A view of the facility and operational requirements involved in performing a manned thermal vacuum test is presented. The requirements fall into two major categories. The first category deals with placing the suited crewmen in a hazardous environment and assuring their safety. The second category deals with the constraints and special requirements involved with a suited crewman operating flight hardware in a 1-G environment. Design areas that deal with man rating a chamber, including fire suppression, emergency repress, emergency power, backups, reliable instrumentation and data systems, communications, television monitoring, biomedical monitoring, material compatibilities, and equipment supporting the Extravehicular Mobility Unit (EMU) are discussed. The operational issues that are peculiar to manned testing such as test rules, test procedures, test protocol, emergency drills, availability of hyperbaric facilities, test team training and certification engineering concerns for a safe mechanical and instrumentation buildup, hazard analysis, and Failure Modes and Effects Analysis are discussed. The constraints and special requirements involved with a suited crewman operating flight hardware in a 1-G environment are addressed.

  15. 32 CFR 707.2 - Man overboard lights.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Man overboard lights. 707.2 Section 707.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY NAVIGATION SPECIAL RULES WITH RESPECT TO ADDITIONAL STATION AND SIGNAL LIGHTS § 707.2 Man overboard lights. Naval vessels may display, as a means of indicating man overboard,...

  16. 32 CFR 707.2 - Man overboard lights.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Man overboard lights. 707.2 Section 707.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY NAVIGATION SPECIAL RULES WITH RESPECT TO ADDITIONAL STATION AND SIGNAL LIGHTS § 707.2 Man overboard lights. Naval vessels may display, as a means of indicating man overboard,...

  17. The Ideal Man and Woman According to University Students

    ERIC Educational Resources Information Center

    Weinstein, Lawrence; Laverghetta, Antonio V.; Peterson, Scott A.

    2009-01-01

    The present study determined if the ideal man has changed over the years and who and what the ideal woman is. We asked students at Cameron University to rate the importance of character traits that define the ideal man and woman. Subjects also provided examples of famous people exemplifying the ideal, good, average, and inferior man and woman. We…

  18. 33 CFR 146.120 - Manning of survival craft.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Manning of survival craft. 146.120 Section 146.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES OPERATIONS Manned OCS Facilities § 146.120 Manning of survival craft. The owner, the owner's agent, or...

  19. 33 CFR 146.120 - Manning of survival craft.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Manning of survival craft. 146.120 Section 146.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES OPERATIONS Manned OCS Facilities § 146.120 Manning of survival craft. The owner, the owner's agent, or...

  20. 33 CFR 146.120 - Manning of survival craft.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Manning of survival craft. 146.120 Section 146.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES OPERATIONS Manned OCS Facilities § 146.120 Manning of survival craft. The owner, the owner's agent, or...

  1. 33 CFR 146.120 - Manning of survival craft.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Manning of survival craft. 146.120 Section 146.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES OPERATIONS Manned OCS Facilities § 146.120 Manning of survival craft. The owner, the owner's agent, or...

  2. 33 CFR 146.120 - Manning of survival craft.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Manning of survival craft. 146.120 Section 146.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES OPERATIONS Manned OCS Facilities § 146.120 Manning of survival craft. The owner, the owner's agent, or...

  3. 32 CFR 707.2 - Man overboard lights.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Man overboard lights. 707.2 Section 707.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY NAVIGATION SPECIAL RULES WITH RESPECT TO ADDITIONAL STATION AND SIGNAL LIGHTS § 707.2 Man overboard lights. Naval vessels may display, as a means of indicating man overboard,...

  4. 32 CFR 707.2 - Man overboard lights.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Man overboard lights. 707.2 Section 707.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY NAVIGATION SPECIAL RULES WITH RESPECT TO ADDITIONAL STATION AND SIGNAL LIGHTS § 707.2 Man overboard lights. Naval vessels may display, as a means of indicating man overboard,...

  5. 32 CFR 707.2 - Man overboard lights.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Man overboard lights. 707.2 Section 707.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY NAVIGATION SPECIAL RULES WITH RESPECT TO ADDITIONAL STATION AND SIGNAL LIGHTS § 707.2 Man overboard lights. Naval vessels may display, as a means of indicating man overboard,...

  6. Man-systems distributed system for Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Lewis, J. L.

    1990-01-01

    Viewgraphs on man-systems distributed system for Space Station Freedom are presented. Topics addressed include: description of man-systems (definition, requirements, scope, subsystems, and topologies); implementation (approach, tools); man-systems interfaces (system to element and system to system); prime/supporting development relationship; selected accomplishments; and technical challenges.

  7. Underwing compression vortex attenuation device

    NASA Technical Reports Server (NTRS)

    Patterson, James C., Jr. (Inventor)

    1993-01-01

    A vortex attenuation device is presented which dissipates a lift-induced vortex generated by a lifting aircraft wing. The device consists of a positive pressure gradient producing means in the form of a compression panel attached to the lower surface of the wing and facing perpendicular to the airflow across the wing. The panel is located between the midpoint of the local wing cord and the trailing edge in the chord-wise direction and at a point which is approximately 55 percent of the wing span as measured from the fuselage center line in the spanwise direction. When deployed in flight, this panel produces a positive pressure gradient aligned with the final roll-up of the total vortex system which interrupts the axial flow in the vortex core and causes the vortex to collapse.

  8. Taurus Lightweight Manned Spacecraft Earth orbiting vehicle

    NASA Technical Reports Server (NTRS)

    Bosset, M.

    1991-01-01

    The Taurus Lightweight Manned Spacecraft (LMS) was developed by students of the University of Maryland's Aerospace Engineering course in Space Vehicle Design. That course required students to design an Alternative Manned Spacecraft (AMS) to augment or replace the Space Transportation System and meet the following design requirements: (1) launch on the Taurus Booster being developed by Orbital Sciences Corporation; (2) 99.9 percent assured crew survival rate; (3) technology cutoff date of 1 Jan. 1991; (4) compatibility with current space administration infrastructure; and (5) first flight by May 1995. The Taurus LMS design meets the above requirements and represents an initial step toward larger and more complex spacecraft. The Taurus LMS has a very limited application when compared to the space shuttle, but it demonstrates that the U.S. can have a safe, reliable, and low-cost space system. The Taurus LMS is a short mission duration spacecraft designed to place one man into low Earth orbit (LEO). The driving factor for this design was the low payload carrying capabilities of the Taurus Booster - 1300 kg to a 300-km orbit. The Taurus LMS design is divided into six major design sections. The Human Factors section deals with the problems of life support and spacecraft cooling. The Propulsion section contains the Abort System, the Orbital Maneuvering System (OMS), the Reaction Control System (RCS), and Power Generation. The thermal protection systems and spacecraft structure are contained in the Structures section. The Avionics section includes Navigation, Attitude Determination, Data Processing, Communication systems, and Sensors. The Mission Analysis section was responsible for ground processing and spacecraft astrodynamics. The Systems Integration Section pulled the above sections together into one spacecraft, and addressed costing and reliability.

  9. Taurus Lightweight Manned Spacecraft Earth orbiting vehicle

    NASA Astrophysics Data System (ADS)

    Bosset, M.

    The Taurus Lightweight Manned Spacecraft (LMS) was developed by students of the University of Maryland's Aerospace Engineering course in Space Vehicle Design. That course required students to design an Alternative Manned Spacecraft (AMS) to augment or replace the Space Transportation System and meet the following design requirements: (1) launch on the Taurus Booster being developed by Orbital Sciences Corporation; (2) 99.9 percent assured crew survival rate; (3) technology cutoff date of 1 Jan. 1991; (4) compatibility with current space administration infrastructure; and (5) first flight by May 1995. The Taurus LMS design meets the above requirements and represents an initial step toward larger and more complex spacecraft. The Taurus LMS has a very limited application when compared to the space shuttle, but it demonstrates that the U.S. can have a safe, reliable, and low-cost space system. The Taurus LMS is a short mission duration spacecraft designed to place one man into low Earth orbit (LEO). The driving factor for this design was the low payload carrying capabilities of the Taurus Booster - 1300 kg to a 300-km orbit. The Taurus LMS design is divided into six major design sections. The Human Factors section deals with the problems of life support and spacecraft cooling. The Propulsion section contains the Abort System, the Orbital Maneuvering System (OMS), the Reaction Control System (RCS), and Power Generation. The thermal protection systems and spacecraft structure are contained in the Structures section. The Avionics section includes Navigation, Attitude Determination, Data Processing, Communication systems, and Sensors. The Mission Analysis section was responsible for ground processing and spacecraft astrodynamics. The Systems Integration Section pulled the above sections together into one spacecraft, and addressed costing and reliability.

  10. Taurus lightweight manned spacecraft Earth orbiting vehicle

    NASA Technical Reports Server (NTRS)

    Chase, Kevin A.; Vandersall, Eric J.; Plotkin, Jennifer; Travisano, Jeffrey J.; Loveless, Dennis; Kaczmarek, Michael; White, Anthony G.; Est, Andy; Bulla, Gregory; Henry, Chris

    1991-01-01

    The Taurus Lightweight Manned Spacecraft (LMS) was developed by students of the University of Maryland's Aerospace Engineering course in Space Vehicle Design. That course required students to design an Alternative Manned Spacecraft (AMS) to augment or replace the Space Transportation System and meet the following design requirements: (1) launch on the Taurus Booster being developed by Orbital Sciences Corporation; (2) 99.9 percent assured crew survival rate; (3) technology cutoff data of 1 Jan. 1991; (4) compatibility with current space administration infrastructure; and (5) first flight by May 1995. The Taurus LMS design meets the above requirements and represents an initial step towards larger and more complex spacecraft. The Taurus LMS has a very limited application when compared to the Space Shuttle, but it demonstrates that the U.S. can have a safe, reliable, and low cost space system. The Taurus LMS is a short mission duration spacecraft designed to place one man into low earth orbit (LEO). The driving factor for this design was the low payload carrying capabilities of the Taurus Booster--1300 kg to a 300 km orbit. The Taurus LMS design is divided into six major design sections. The human factors system deals with the problems of life support and spacecraft cooling. The propulsion section contains the abort system, the Orbital Maneuvering System (OMS), the Reaction Control System (RCS), and power generation. The thermal protection systems and spacecraft structure are contained in the structures section. The avionics section includes navigation, attitude determination, data processing, communication systems, and sensors. The mission analysis section was responsible for ground processing and spacecraft astrodynamics. The systems integration section pulled the above sections together into one spacecraft and addressed costing and reliability.

  11. Manned Mars mission health maintenance facility

    NASA Technical Reports Server (NTRS)

    Degioanni, Joseph C.

    1986-01-01

    The Health Maintenance Facility (HMF) requirements which enable/enhance manned Mars missions (MMMs) are addressed. It does not attempt to resolve any issues that may affect the feasibility of any given element in the HMF. Reference is made to current work being conducted in the design of the space station HMF. The HMF requirements are discussed within the context of two distinctly different scenarios: HMF as part of the Mars surface infrastructure, and HMF as part of the nine months translation from low Earth orbit to Mars orbit. Requirements for an HMF are provided, and a concept of HMF is shown.

  12. Assessment of man's thermal comfort in practice

    PubMed Central

    Fanger, P. O.

    1973-01-01

    Fanger, P. O. (1973).British Journal of Industrial Medicine,30, 313-324. Assessment of man's thermal comfort in practice. A review is given of existing knowledge regarding the conditions for thermal comfort. Both physiological and environmental comfort conditions are discussed. Comfort criteria are shown diagrammatically, and their application is illustrated by numerous practical examples. Furthermore, the effect on the comfort conditions of age, adaptation, sex, seasonal and circadian rhythm, and unilateral heating or cooling of the body is discussed. The term `climate monotony' is considered. A method is recommended for the evaluation of the quality of thermal environments in practice. Images PMID:4584998

  13. Pantex Falling Man - Independent Review Panel Report.

    SciTech Connect

    Bertolini, Louis; Brannon, Nathan; Olson, Jared; Price, Bernard; Wardle, Robert; Steinzig, Mike; Winfield, Michael

    2014-11-01

    Consolidated Nuclear Security (CNS) Pantex took the initiative to organize a Review Panel of subject matter experts to independently assess the adequacy of the Pantex Tripping Man Analysis methodology. The purpose of this report is to capture the details of the assessment including the scope, approach, results, and detailed Appendices. Along with the assessment of the analysis methodology, the panel evaluated the adequacy with which the methodology was applied as well as congruence with Department of Energy (DOE) standards 3009 and 3016. The approach included the review of relevant documentation, interactive discussion with Pantex staff, and the iterative process of evaluating critical lines of inquiry.

  14. Analysis of evoked lumbosacral potentials in man.

    PubMed Central

    Delbeke, J; McComas, A J; Kopec, S J

    1978-01-01

    Surface electrodes have been used to record potentials evoked in the lumbosacral region of 15 healthy volunteers after tibial nerve stimulation. By monitoring the M waves and H reflexes in the triceps surae muslces and by comparing the responses recorded over the roots with those over the lower cord, it was possible to identify the neural substrates responsible for several of the components in the responses. The findings are compared with those of previous studies in man and in other mammalian preparations. PMID:650237

  15. Analysis of evoked lumbosacral potentials in man.

    PubMed

    Delbeke, J; McComas, A J; Kopec, S J

    1978-04-01

    Surface electrodes have been used to record potentials evoked in the lumbosacral region of 15 healthy volunteers after tibial nerve stimulation. By monitoring the M waves and H reflexes in the triceps surae muslces and by comparing the responses recorded over the roots with those over the lower cord, it was possible to identify the neural substrates responsible for several of the components in the responses. The findings are compared with those of previous studies in man and in other mammalian preparations. PMID:650237

  16. Nuclear propulsion tradeoffs for manned Mars missions

    SciTech Connect

    Walton, L.A.; Malloy, J.D. )

    1991-01-05

    A conjunction class split/sprint manned Mars exploration mission was studied to evaluate tradeoffs in performance characteristics of nuclear thermal rockets. A Particle Bed Reactor-based nuclear thermal rocket was found to offer a 38% to 52% total mass savings compared with a NERVA-based nuclear thermal rocket for this mission. This advantage is primarily due to the higher thrust-to-weight ratio of the Particle Bed Reactor nuclear rocket. The mission is enabled by nuclear thermal rockets. It cannot be performed practically using chemical propulsion.

  17. Design and Construction of Manned Lunar Base

    NASA Astrophysics Data System (ADS)

    Li, Zhijie

    2016-07-01

    Building manned lunar base is one of the core aims of human lunar exploration project, which is also an important way to carry out the exploitation and utilization of lunar in situ resources. The most important part of manned lunar base is the design and construction of living habitation and many factors should be considered including science objective and site selection. Through investigating and research, the scientific goals of manned lunar base should be status and characteristics ascertainment of lunar available in situ resources, then developing necessary scientific experiments and utilization of lunar in situ resources by using special environment conditions of lunar surface. The site selection strategy of manned lunar base should rely on scientific goals according to special lunar surface environment and engineering capacity constraints, meanwhile, consulting the landing sites of foreign unmanned and manned lunar exploration, and choosing different typical regions of lunar surface and analyzing the landform and physiognomy, reachability, thermal environment, sunlight condition, micro meteoroids protection and utilization of in situ resources, after these steps, a logical lunar living habitation site should be confirmed. This paper brings out and compares three kinds of configurations with fabricating processes of manned lunar base, including rigid module, flexible and construction module manned lunar base. 1.The rigid habitation module is usually made by metal materials. The design and fabrication may consult the experience of space station, hence with mature technique. Because this configuration cannot be folded or deployed, which not only afford limit working and living room for astronauts, but also needs repetitious cargo transit between earth and moon for lunar base extending. 2. The flexible module habitation can be folded in fairing while launching. When deploying on moon, the configuration can be inflatable or mechanically-deployed, which means under

  18. Manned Mars mission radiation environment and radiobiology

    NASA Technical Reports Server (NTRS)

    Nachtwey, D. S.

    1986-01-01

    Potential radiation hazards to crew members on manned Mars missions are discussed. It deals briefly with radiation sources and environments likely to be encountered during various phases of such missions, providing quantitative estimates of these environments. Also provided are quantitative data and discussions on the implications of such radiation on the human body. Various sorts of protective measures are suggested. Recent re-evaluation of allowable dose limits by the National Council of Radiation Protection is discussed, and potential implications from such activity are assessed.

  19. Responses evoked from man by acoustic stimulation

    NASA Technical Reports Server (NTRS)

    Galambos, R.; Hecox, K.; Picton, T.

    1974-01-01

    Clicks and other acoustic stimuli evoke time-locked responses from the brain of man. The properties of the waves recordable within the interval from 1 to 10 msec after the stimuli strike the eardrum are discussed along with factors influencing the waves in the 100 to 500 msec epoch. So-called brainstem responses from a normal young adult are considered. No waves were observed for clicks to weak to be heard. With increasing stimulus strength the waves become larger in amplitude and their latency shortens.

  20. Man-caused seismicity of Kuzbass

    NASA Astrophysics Data System (ADS)

    Emanov, Alexandr; Emanov, Alexey; Leskova, Ekaterina; Fateyev, Alexandr

    2010-05-01

    A natural seismicity of Kuznetsk Basin is confined in the main to mountain frame of Kuznetsk hollow. In this paper materials of experimental work with local station networks within sediment basin are presented. Two types of seismicity display within Kuznetsk hollow have been understood: first, man-caused seismic processes, confined to mine working and concentrated on depths up to one and a half of km; secondly, seismic activations on depths of 2-56 km, not coordinated in plan with coal mines. Every of studied seismic activations consists of large quantity of earthquakes of small powers (Ms=1-3). From one to first tens of earthquakes were recorded in a day. The earthquakes near mine working shift in space along with mine working, and seismic process become stronger at the instant a coal-plough machine is operated, and slacken at the instant the preventive works are executed. The seismic processes near three lavas in Kuznetsk Basin have been studied in detail. Uplift is the most typical focal mechanism. Activated zone near mine working reach in diameter 1-1,5 km. Seismic activations not linked with mine working testify that the subsoil of Kuznetsk hollow remain in stress state in whole. The most probable causes of man-caused action on hollow are processes, coupled with change of physical state of rocks at loss of methane from large volume or change by mine working of rock watering in large volume. In this case condensed rocks, lost gas and water, can press out upwards, realizing the reverse fault mechanism of earthquakes. A combination of stress state of hollow with man-caused action at deep mining may account for incipient activations in Kuznetsk Basin. Today earthquakes happen mainly under mine workings, though damages of workings themselves do not happen, but intensive shaking on surface calls for intent study of so dangerous phenomena. In 2009 replicates of the experiment on research of seismic activations in area of before investigated lavas have been conducted

  1. Geohazards: Natural and man-made

    SciTech Connect

    McCall, G.J.H.; Laming, D.J.C.; Scott, S.C.

    1992-01-01

    This book of conference presentations from a meeting of the Geological Society of London in 1989 includes 20 papers grouped in 5 sections. Sections include the following: volcanos; earthquakes; landslides; quiet hazards such as sea-level changes and loss of soils or biodiversity; discussion of the question of what can be done to reduce such disasters. Interaction of man's activities to initiate disasters, to increase the scope of disasters and/or to mitigate them is included in a number of papers. In the fourth section a final paper provides a summary of the food-soil, energy-climate, waste-garbage, and water-contamination interactions.

  2. Centromere organization in man and mouse

    SciTech Connect

    Jeppesen, P.; Mitchell, A.; Kipling, D.; Nicol, L.

    1993-12-31

    The kinetochore, located at the primary constriction or centromere in mammalian metaphase chromosomes, is the site of attachment of spindle microtubules to the mitotic chromosome, and is thus essential for correct chromosome movement and segregation at anaphase. Errors in organization of the kinetochore and/or centromere may therefore lead to non-disjunction and aneuploidy. The centromeres of most, if not all, mammalian chromosomes contain repetitive DNA sequences, which are observed at the cytogenetic level as heterochromatin. We have combined immunofluorescence with primed in situ hybridization (PRINS) techniques to study the organization of repetitive DNA families in relation to chromosomal proteins located at centromeres in both man and mouse species.

  3. Nuclear propulsion tradeoffs for manned Mars missions

    NASA Astrophysics Data System (ADS)

    Walton, Lewis A.; Malloy W Nuclear Technologies, John D.

    1991-01-01

    A conjunction class split/sprint manned Mars exploration mission was studied to evaluate tradeoffs in performance characteristics of nuclear thermal rockets. A Particle Bed Reactor-based nuclear thermal rocket was found to offer a 38% to 52% total mass savings compared with a NERVA-based nuclear thermal rocket for this mission. This advantage is primarily due to the higher thrust-to-weight ratio of the Particle Bed Reactor nuclear rocket. The mission is enabled by nuclear thermal rockets. It cannot be performed practically using chemical propulsion.

  4. Nuclear propulsion tradeoffs for manned Mars missions

    NASA Astrophysics Data System (ADS)

    Walton, Lewis A.; Malloy, John D.

    A conjunction class split/sprint manned Mars exploration mission was studied to evaluate tradeoffs in performance characteristics of nuclear thermal rockets. A Particle Bed Reactor-based nuclear thermal rocket was found to offer a 38 to 52 percent total mass savings compared with a NERVA-based nuclear thermal rocket for this mission. This advantage is primarily due to the higher thrust-to-weight ratio of the Particle Bed Reactor nuclear rocket. The mission is enabled by nuclear thermal rockets. It cannot be performed practically using chemical propulsion.

  5. Man-machine interfaces in health care

    NASA Technical Reports Server (NTRS)

    Charles, Steve; Williams, Roy E.

    1991-01-01

    The surgeon, like the pilot, is confronted with an ever increasing volume of voice, data, and image input. Simultaneously, the surgeon must control a rapidly growing number of devices to deliver care to the patient. The broad disciplines of man-machine interface design, systems integration, and teleoperation will play a role in the operating room of the future. The purpose of this communication is to report the incorporation of these design concepts into new surgical and laser delivery systems. A review of each general problem area and the systems under development to solve the problems are presented.

  6. What computers mean for man and society.

    PubMed

    Simon, H A

    1977-03-18

    From an economic standpoint, the modern computer is simply the most recent of a long line of new technologies that increase productivity and cause a gradual shift from manufacturing to service employment. The empirical evidence provides no support for the claim sometimes made that the computer "mechanizes" and "dehumanizes" work. Perhaps the greatest significance of the computer lies in its impact on Man's view of himself. No longer accepting the geocentric view of the universe, he now begins to learn that mind, too, is a phenomenon of nature, explainable in terms of simple mechanisms. Thus the computer aids him to obey, for the first time, the ancient injunction, "Know thyself." PMID:17789730

  7. Landing Energy Dissipation for Manned Reentry Vehicles

    NASA Technical Reports Server (NTRS)

    Fisher, Loyd. L.

    1960-01-01

    The film shows experimental investigations to determine the landing-energy-dissipation characteristics for several types of landing gear for manned reentry vehicles. The landing vehicles are considered in two categories: those having essentially vertical-descent paths, the parachute-supported vehicles, and those having essentially horizontal paths, the lifting vehicles. The energy-dissipation devices include crushable materials such as foamed plastics and honeycomb for internal application in couch-support systems, yielding metal elements as part of the structure of capsules or as alternates for oleos in landing-gear struts, inflatable bags, braking rockets, and shaped surfaces for water impact.

  8. Can man be protected against rabies?

    PubMed Central

    Meyer, K. F.

    1954-01-01

    The literature dealing with the protection of man against rabies over the past 70 years in many parts of the world is reviewed, and the salient problems of our present state of knowledge analysed. The author discusses the measures currently in use for eliminating canine rabies by quarantine, regulation of the dog population, and—in particular—mass vaccination of dogs, with a detailed survey of the questions of immunological research which this method raises. Measures for suppressing the disease in other vectors are also described. It is concluded that, given effective education of the public and the widespread use of canine mass vaccination, human rabies is a preventable disease. PMID:13182607

  9. Adaptive myelination from fish to man.

    PubMed

    Baraban, Marion; Mensch, Sigrid; Lyons, David A

    2016-06-15

    Myelinated axons with nodes of Ranvier are an evolutionary elaboration common to essentially all jawed vertebrates. Myelin made by Schwann cells in our peripheral nervous system and oligodendrocytes in our central nervous system has been long known to facilitate rapid energy efficient nerve impulse propagation. However, it is now also clear, particularly in the central nervous system, that myelin is not a simple static insulator but that it is dynamically regulated throughout development and life. New myelin sheaths can be made by newly differentiating oligodendrocytes, and mature myelin sheaths can be stimulated to grow again in the adult. Furthermore, numerous studies in models from fish to man indicate that neuronal activity can affect distinct stages of oligodendrocyte development and the process of myelination itself. This begs questions as to how these effects of activity are mediated at a cellular and molecular level and whether activity-driven adaptive myelination is a feature common to all myelinated axons, or indeed all oligodendrocytes, or is specific to cells or circuits with particular functions. Here we review the recent literature on this topic, elaborate on the key outstanding questions in the field, and look forward to future studies that incorporate investigations in systems from fish to man that will provide further insight into this fundamental aspect of nervous system plasticity. This article is part of a Special Issue entitled SI: Myelin Evolution. PMID:26498877

  10. Toxicological safeguards in the manned Mars missions

    NASA Technical Reports Server (NTRS)

    Coleman, Martin E.

    1986-01-01

    Safeguards against toxic chemical exposures during manned Mars missions (MMMs) will be important for the maintenance of crew health and the accomplishment of mission objectives. Potential sources include offgassing, thermodegradation or combustion of materials, metabolic products of crew members, and escape of chemical from containment. Spacecraft maximum allowable concentration (SMAC) limits will have to be established for potential contaminants during the MMMs. The following factors will be used in establishing these limits: duration of mission, simultaneous exposure to other contaminants, deconditioning of crew members after long periods of reduced gravity, and simultaneous exposure to ionizing radiation. Atmospheric contaminant levels in all compartments of the transit spacecraft and Manned Mars Station (MMS) will be monitored at frequent intervals with a real time analyzer. This analyzer will be highly automated, requiring minimal crew time and expertise. The atmospheric analyzer will find other usages during the MMMs such as analyzing Martian atmospheres and soils, exhaled breath and body fluids of crew members, and reaction products in chemical processing facilities.

  11. Manned Mars mission accommodation: Sprint mission

    NASA Technical Reports Server (NTRS)

    Cirillo, William M.; Kaszubowski, Martin J.; Ayers, J. Kirk; Llewellyn, Charles P.; Weidman, Deene J.; Meredith, Barry D.

    1988-01-01

    The results of a study conducted at the NASA-LaRC to assess the impacts on the Phase 2 Space Station of Accommodating a Manned Mission to Mars are documented. In addition, several candidate transportation node configurations are presented to accommodate the assembly and verification of the Mars Mission vehicles. This study includes an identification of a life science research program that would need to be completed, on-orbit, prior to mission departure and an assessment of the necessary orbital technology development and demonstration program needed to accomplish the mission. Also included is an analysis of the configuration mass properties and a preliminary analysis of the Space Station control system sizing that would be required to control the station. Results of the study indicate the Phase 2 Space Station can support a manned mission to Mars with the addition of a supporting infrastructure that includes a propellant depot, assembly hangar, and a heavy lift launch vehicle to support the large launch requirements.

  12. Proposal for a remotely manned space station

    NASA Technical Reports Server (NTRS)

    Minsky, Marvin

    1990-01-01

    The United States is in trouble in space. The costs of the proposed Space Station Freedom have grown beyond reach, and the present design is obsolete. The trouble has come from imagining that there are only two alternatives: manned vs. unmanned. Both choices have led us into designs that do not appear to be practical. On one side, the United States simply does not possess the robotic technology needed to operate or assemble a sophisticated unmanned space station. On the other side, the manned designs that are now under way seem far too costly and dangerous, with all of its thousands of extravehicular activity (EVA) hours. More would be accomplished at far less cost by proceeding in a different way. The design of a space station made of modular, Erector Set-like parts is proposed which is to be assembled using earth-based remotely-controlled binary-tree telerobots. Earth-based workers could be trained to build the station in space using simulators. A small preassembled spacecraft would be launched with a few telerobots, and then, telerobots could be ferried into orbit along with stocks of additional parts. Trained terrestrial workers would remotely assemble a larger station, and materials for additional power and life support systems could be launched. Finally, human scientists and explorers could be sent to the space station. Other aspects of such a space station program are discussed.

  13. GridMan: A grid manipulation system

    NASA Technical Reports Server (NTRS)

    Eiseman, Peter R.; Wang, Zhu

    1992-01-01

    GridMan is an interactive grid manipulation system. It operates on grids to produce new grids which conform to user demands. The input grids are not constrained to come from any particular source. They may be generated by algebraic methods, elliptic methods, hyperbolic methods, parabolic methods, or some combination of methods. The methods are included in the various available structured grid generation codes. These codes perform the basic assembly function for the various elements of the initial grid. For block structured grids, the assembly can be quite complex due to a large number of clock corners, edges, and faces for which various connections and orientations must be properly identified. The grid generation codes are distinguished among themselves by their balance between interactive and automatic actions and by their modest variations in control. The basic form of GridMan provides a much more substantial level of grid control and will take its input from any of the structured grid generation codes. The communication link to the outside codes is a data file which contains the grid or section of grid.

  14. Manned Mars mission accommodation: Sprint mission

    NASA Astrophysics Data System (ADS)

    Cirillo, William M.; Kaszubowski, Martin J.; Ayers, J. Kirk; Llewellyn, Charles P.; Weidman, Deene J.; Meredith, Barry D.

    1988-04-01

    The results of a study conducted at the NASA-LaRC to assess the impacts on the Phase 2 Space Station of Accommodating a Manned Mission to Mars are documented. In addition, several candidate transportation node configurations are presented to accommodate the assembly and verification of the Mars Mission vehicles. This study includes an identification of a life science research program that would need to be completed, on-orbit, prior to mission departure and an assessment of the necessary orbital technology development and demonstration program needed to accomplish the mission. Also included is an analysis of the configuration mass properties and a preliminary analysis of the Space Station control system sizing that would be required to control the station. Results of the study indicate the Phase 2 Space Station can support a manned mission to Mars with the addition of a supporting infrastructure that includes a propellant depot, assembly hanger, and a heavy lift launch vehicle to support the large launch requirements.

  15. Radiation Shielding for Manned Deep Space Missions

    NASA Technical Reports Server (NTRS)

    Adams, James H., Jr.

    2003-01-01

    The arrival of the Expedition 1 Crew at the International Space Station represents the beginning of the continuous presence of man in space. Already we are deploying astronauts and cosmonauts for missions of approx. 6 months onboard the ISS. In the future we can anticipate that more people will be in space and they will be there for longer periods. Even with 6-months deployments to the ISS, the radiation exposure that crew members receive is approaching the exposure limits imposed by the governments of the space- faring nations. In the future we can expect radiation protection to be a dominant consideration for long manned missions. Recognizing this, NASA has expanded their research program on radiation health. This program has three components, bioastronautics, fundamental biology and radiation shielding materials. Bioastronautics is concerned with the investigating the effects of radiation on humans. Fundamental biology investigates the basic mechanisms of radiation damage to tissue. Radiation shielding materials research focuses on developing accurate computational tools to predict the radiation shielding effectiveness of materials. It also investigates new materials that can be used for spacecraft. The radiation shielding materials program will be described and examples of results from the ongoing research will be shown.

  16. [Anaesthetic management of Stiff Man syndrome].

    PubMed

    Marín, T; Hernando, D; Kinast, N; Churruca, I; Sabate, S

    2015-04-01

    Stiff Man syndrome or stiff-person syndrome is a rare autoimmune disorder. It is characterized by increased axial muscular tone and limb musculature, and painful spasms triggered by stimulus. The case is presented of a 44-year-old man with stiff-person syndrome undergoing an injection of botulinum toxin in the urethral sphincter under sedation. Before induction, all the surgical team were ready in order to minimise the anaesthetic time. The patient was monitored by continuous ECG, SpO2 and non-invasive blood pressure. He was induced with fractional dose of propofol 150 mg, fentanyl 50 μg and midazolam 1mg. Despite careful titration, the patient had an O2 saturation level of 90%,which was resolved by manual ventilation. There was no muscle rigidity or spasm during the operation. Post-operative recovery was uneventful and the patient was discharged 2 days later. A review of other cases is presented. The anaesthetic concern in patients with stiff-person syndrome is the interaction between the anaesthetic agents, the preoperative medication, and the GABA system. For a safe anaesthetic management, total intravenous anaesthesia is recommended instead of inhalation anaesthetics, as well as the close monitoring of the respiratory function and the application of the electrical nerve stimulator when neuromuscular blockers are used. PMID:25060949

  17. Postural control in man: the phylogenetic perspective.

    PubMed

    Gramsbergen, Albert

    2005-01-01

    Erect posture in man is a recent affordance from an evolutionary perspective. About eight million years ago, the stock from which modern humans derived split off from the ape family, and from around sixty-thousand years ago, modern man developed. Upright gait and manipulations while standing pose intricate cybernetic problems for postural control. The trunk, having an older evolutionary history than the extremities, is innervated by medially descending motor systems and extremity muscles by the more recent, laterally descending systems. Movements obviously require concerted actions from both systems. Research in rats has demonstrated the interdependencies between postural control and the development of fluent walking. Only 15 days after birth, adult-like fluent locomotion emerges and is critically dependent upon postural development. Vesttibular deprivation induces a retardation in postural development and, consequently, a retarded development of adult-like locomotion. The cerebellum obviously has an important role in mutual adjustments in postural control and extremity movements, or, in coupling the phylogenetic older and newer structures. In the human, the cerebellum develops partly after birth and therefore is vulnerable to adverse perinatal influences. Such vulnerability seems to justify focusing our scientific research efforts onto the development of this structure. PMID:16097476

  18. Man-portable networked sensor system

    NASA Astrophysics Data System (ADS)

    Bryan, W. D.; Nguyen, Hoa G.; Gage, Douglas W.

    1998-08-01

    The Man-Portable Networked Sensor System (MPNSS), with its baseline sensor suite of a pan/tilt unit with video and FLIR cameras and laser rangefinder, functions in a distributed network of remote sensing packages and control stations designed to provide a rapidly deployable, extended-range surveillance capability for a wide variety of security operations and other tactical missions. While first developed as a man-portable prototype, these sensor packages can also be deployed on UGVs and UAVs, and a copy of this package been demonstrated flying on the Sikorsky Cypher VTOL UAV in counterdrug and MOUNT scenarios. The system makes maximum use of COTS components for sensing, processing, and communications, and of both established and emerging standard communications networking protocols and system integration techniques. This paper will discuss the technical issues involved in: (1) system integration using COTS components and emerging bus standards, (2) flexible networking for a scalable system, and (3) the human interface designed to maximize information presentation to the warfighter in battle situations.

  19. [Genodermatosis in man and animal. Comparative overview].

    PubMed

    Küster, W; Happle, R

    1983-11-01

    Fourteen monogenic cutaneous disorders of man are compared to similar gene defects in animals. The traits are classified into two groups. In the first group, an identity (homology) of the underlying gene defects is likely. This group includes oculo-cutaneous albinism, Chédiak-Higashi syndrome, aplasia cutis congenita, Ehlers-Danlos syndrome (type I), hypohidrotic ectodermal dysplasia of the Christ-Siemens-Touraine type, X-linked dominant chondrodysplasia punctata, ichthyosis congenita gravis, Menkes syndrome, erythropoetic porphyria, porphyria cutanea tarda, and acrodermatitis enteropathica. In the second group, the traits are similar but the question of their homology cannot be settled. It includes alopecia congenita, hidrotic ectodermal dysplasia of the Clouston type, and hereditary lymphedema. The existence of identical mutations in man and animals provides evidence for the close relationship between the various mammalian species. Homologous traits affecting the skin are of practical importance since the use of these animal models may help to answer those questions which cannot be answered by performing research in human patients. PMID:6358130

  20. First-in-Man, Mitral Valve-in-Valve Transcatheter Implantation Through an Innovative Minimally Invasive Surgical Approach.

    PubMed

    Muneretto, Claudio; Ettori, Federica; Mazzitelli, Domenico; Curello, Salvatore; Chiari, Ermanna; Mastropierro, Rosy; Maffeo, Diego; Bisleri, Gianluigi

    2015-08-01

    Degeneration of a surgically implanted valve bioprosthesis may occur in elderly, frail patients with an extremely high risk to undergo redo cardiac surgery. Transapical or fully percutaneous transseptal approaches have been described in order to treat degenerated aortic and mitral bioprosthesis. We performed the first-in-man successful mitral transcatheter valve delivery with a valve-in-valve technique through an innovative route; ie, a video-assisted endoscopic direct access to the left atrium, in an 82-year-old patient who previously underwent surgical replacement of the mitral valve and with a prohibitive surgical risk. PMID:26234847

  1. "A Man's Gotta Do What a Man's Gotta Do!" Masculinity and Manhood in Social Studies Education

    ERIC Educational Resources Information Center

    Hewitt, William L.

    2004-01-01

    Men in the United States are products of society's assumptions about what it means to "be a man." Throughout American history, these assumptions have supported aggression, conflict, and war. Seeing American troops in Iraq conjures comparisons not only to past military ventures but also to the changing face of the masculine warrior. One might see…

  2. The Implementation of Madrasah-Based Management (MBM) at Man 1 and Man 2 Serang City, Banten, Indonesia--A Comparative Study

    ERIC Educational Resources Information Center

    Muhajir

    2016-01-01

    This study aims to reveal how the real condition of management of Madrasah Aliyah Negeri (MAN) or Islamic Senior High School in Serang is, how the understanding of Madrasah-Based Management (MBM) for the people of MAN 2 and MAN 1 Serang is, and how the implementation of MBM in MAN 2 and MAN 1 Serang. This study has a substantial meaning, both…

  3. A middle-aged man presenting with unexplained mucosal erosions and progressive dyspnoea.

    PubMed

    Healy, W J; Peters, S; Nana-Sinkam, S P

    2015-01-01

    Paraneoplastic pemphigus (PNP) is a rare syndrome driven by antibodies (IgG) binding to desmogleins and other epidermal proteins leading to skin erosions. In rare instances, these same IgG proteins may also target the bronchial mucosa leading to an irreversible fibrotic reaction within the epithelium and subsequent obstructive lung disease. A 51-year-old man presented to the emergency department with 2-3-month history of dyspnoea as well as oral and genital ulcerations and inguinal lymphadenopathy. The ulcerations were biopsied and proven to be consistent with pemphigus. Subsequent inguinal lymph node biopsy implicated the hyaline-vascular variant of Castleman's disease (CD), as the primary cause of the patient's pemphigus. The patient underwent pulmonary function testing that demonstrated severe airflow obstruction. The patient was diagnosed with PNP and associated bronchiolitis obliterans syndrome (BOS). He was treated with rituximab for his CD, and oral and inhaled corticosteroids along with azithromycin for his BOS. PMID:25953579

  4. Departure phase aborts for manned Mars missions

    NASA Astrophysics Data System (ADS)

    Dissel, Adam F.

    NASA goals are set on resumption of human activity on the Moon and extending manned missions to Mars. Abort options are key elements of any system designed to safeguard human lives and stated requirements stipulate the provision of an abort capability throughout the mission. The present investigation will focus on the formulation and analysis of possible abort modes during the Earth departure phase of manned Mars interplanetary transfers. Though of short duration, the departure phase encompasses a mission timeline where failures have frequently become manifest in historical manned spacecraft necessitating the inclusion of a departure phase abort capability. Investigated abort modes included aborts to atmospheric entry, and to Earth or Moon orbit. Considered interplanetary trajectory types included conjunction, opposition, and free-return trajectory classes. All abort modes were analyzed for aborts initiated at multiple points along each of these possible departure trajectories across all launch opportunities of the fifteen-year Earth-Mars inertial period. The consistently low departure velocities of the conjunction trajectories facilitated the greatest abort capability. An analysis of Mars transportation architectures was performed to determine the amount of available delta V inherent in each candidate architecture for executing departure aborts. Results indicate that a delta V of at least 4 km/s is required to achieve a continuous departure phase entry abort capability with abort flights less than three weeks duration for all transfer opportunity years. Less demanding transfer years have a corresponding increase in capability. The Earth orbit abort mode does not become widely achievable until more than 6 km/s delta V is provided; a capacity not manifest in any considered architecture. Optimization of the Moon abort mode resulted in slight departure date shifts to achieve improved lunar alignments. The Moon abort mode is only widely achievable for conjunction

  5. Sleep monitoring: the second manned Skylab mission.

    PubMed

    Frost, J D; Shumate, W H; Salamy, J G; Booher, C R

    1976-04-01

    The first objective measurements of man's ability to obtain adequate sleep during prolonged space flight were made during the three manned Skylab missions. EEG, EOG, and head-motion signals were acquired during sleep by use of an elastic recording cap containing sponge electrodes and an attached miniature preamplifier/accelerometer unit. A control-panel assembly, mounted in the sleep compartment, tested electrodes, preserved analog signals, and automatically analyzed data in real time (providing a telementered indication of sleep stage). One subject was studied during each manned mission and, while there was considerable variation among individuals, several characteristics were common to all three: stage 3 sleep increased during the flight and decreased in the postflight period; stage 4 was consistently decreased postflight, although this stage was variable during the flight; stage REM (rapid eye movement) was elevated, and REM latency decreased in the late postflight period (after day 3 postrecovery); and the number of awakenings during sleep either showed no change or decreased during the flight. In only the 28-d mission (Skylab 2) was there a significant decrease in total sleep time; in that case it was a result of voluntarily reduced rest time and was not due to difficulty in sleeping nor frequent awakening. The subject on the 84-d mission (Skylab 4) experienced more difficulty in the first half of the flight, showing a decreased total sleep time and increased sleep latency, but this resolved itself with time. Sleep latency presented no problem in the other flights. While many of the findings are statistically significant, in no case would they be expected to produce a noticeable decrement of performance capability. These findings suggest that men are able to obtain adequate sleep in regularly scheduled 8-h rest periods during extended space flights. It seems likely, based upon these results, that the problems encountered in earlier space flights did not arise

  6. Comparative Effects of Statin Therapy versus Renin-Angiotensin System Blocking Therapy in Patients with Ischemic Heart Failure Who Underwent Percutaneous Coronary Intervention

    PubMed Central

    Won, Jumin; Jeong, Myung Ho; Park, Hyuk Jin; Kim, Min Chul; Kim, Woo Jin; Kim, Hyun Kuk; Sim, Doo Sun; Kim, Ju Han; Ahn, Youngkeun; Cho, Jeong Gwan; Park, Jong Chun

    2016-01-01

    Statins and renin-angiotensin system (RAS) blockers are key drugs for treating patients with an acute myocardial infarction (AMI). This study was designed to show the association between treatment with statins or RAS blockers and clinical outcomes and the efficacy of two drug combination therapies in patients with ischemic heart failure (IHF) who underwent revascularization for an AMI. A total of 804 AMI patients with a left ventricular ejection fraction <40% who undertook percutaneous coronary interventions (PCI) were analyzed using the Korea Acute Myocardial Infarction Registry (KAMIR). They were divided into four groups according to the use of medications [Group I: combination of statin and RAS blocker (n=611), Group II: statin alone (n=112), Group III: RAS blocker alone (n=53), Group IV: neither treatment (n=28)]. The cumulative incidence of major adverse cardiac and cerebrovascular events (MACCEs) and independent predictors of MACCEs were investigated. Over a median follow-up study of nearly 1 year, MACCEs had occurred in 48 patients (7.9%) in Group I, 16 patients (14.3%) in Group II, 3 patients (5.7%) in Group III, 7 patients (21.4%) in Group IV (p=0.013). Groups using RAS blocker (Group I and III) showed better clinical outcomes compared with the other groups. By multivariate analysis, use of RAS blockers was the most powerful independent predictor of MACCEs in patients with IHF who underwent PCI (odds ratio 0.469, 95% confidence interval 0.285-0.772; p=0.003), but statin therapy was not found to be an independent predictor. The use of RAS blockers, but not statins, was associated with better clinical outcomes in patients with IHF who underwent PCI. PMID:27231678

  7. Man/computer communication in a space environment

    NASA Technical Reports Server (NTRS)

    Hodges, B. C.; Montoya, G.

    1973-01-01

    The present work reports on a study of the technology required to advance the state of the art in man/machine communications. The study involved the development and demonstration of both hardware and software to effectively implement man/computer interactive channels of communication. While tactile and visual man/computer communications equipment are standard methods of interaction with machines, man's speech is a natural media for inquiry and control. As part of this study, a word recognition unit was developed capable of recognizing a minimum of one hundred different words or sentences in any one of the currently used conversational languages. The study has proven that efficiency in communication between man and computer can be achieved when the vocabulary to be used is structured in a manner compatible with the rigid communication requirements of the machine while at the same time responsive to the informational needs of the man.

  8. Design and finite element analysis of oval man way

    SciTech Connect

    Hari, Y.; Gryder, B.

    1996-12-01

    This paper presents the design of an oval man way in the side wall of a cylindrical pressure vessel. ASME Code Section 8 is used to obtain the design parameters of the oval man way, man way cover and bolts. The code calculations require some assumptions which may not be valid. A typical design example is taken. STAAD III finite element code with plate elements is used to model the oval man way, man way cover and bolts. The stresses calculated using ASME Code Section 8 and other analytical formulas for plate and shells are compared with the stresses obtained by Finite Element Modeling. This paper gives the designer of oval man way the ability to perform a finite element analysis and compare it with the analytical calculations and assumptions made. This gives added confidence to the designer as to the validity of his calculations and assumptions.

  9. Successful pregnancy following transfer of frozen-thawed embryos in a patient with pseudomyxoma peritonei who underwent peritonectomy and bilateral oophorectomy

    PubMed Central

    Michaan, Nadav; Many, Ariel; Amit, Ami; Azem, Foad

    2012-01-01

    Pseudomyxoma peritonei is a rare, chronic relapsing disease in which tumor cells in the abdomen produce excessive mucin with a significant mortality rate. We describe a young unmarried nulligrava who underwent fertility preservation by in vitro fertilisation and embryo cryopreservation prior to radical surgery and adjuvant chemotherapy. Pregnancy was achieved, although complicated by obstructive uropathy. She delivered a healthy infant at 32 weeks' gestation. The few descriptions of fertility and pregnancy outcome in pseudomyxoma peritonei that appear in the literature are reviewed. PMID:22523631

  10. Successful pregnancy following transfer of frozen-thawed embryos in a patient with pseudomyxoma peritonei who underwent peritonectomy and bilateral oophorectomy.

    PubMed

    Laskov, Ido; Michaan, Nadav; Many, Ariel; Amit, Ami; Azem, Foad

    2012-04-01

    Pseudomyxoma peritonei is a rare, chronic relapsing disease in which tumor cells in the abdomen produce excessive mucin with a significant mortality rate. We describe a young unmarried nulligrava who underwent fertility preservation by in vitro fertilisation and embryo cryopreservation prior to radical surgery and adjuvant chemotherapy. Pregnancy was achieved, although complicated by obstructive uropathy. She delivered a healthy infant at 32 weeks' gestation. The few descriptions of fertility and pregnancy outcome in pseudomyxoma peritonei that appear in the literature are reviewed. PMID:22523631

  11. Trauma on the Isle of Man.

    PubMed Central

    Hackney, R G; Varley, G; Stevens, D; Green, A

    1993-01-01

    The Isle of Man Tourist Trophy motorcycle races remain one of the most popular venues for motorcycle races. This is despite the reduced status of the event. The reason for the loss of world championship and formula one status is the nature of the road racing circuit itself. The twisting narrow roads are only closed to the public at certain times during the practice and race weeks. Motorcycling visitors to the event attempt to emulate their heroes on machines capable of high speeds. Casualties from both visitors and racers are dealt with efficiently by an expanded medical service. This includes the use of an aeromedical evacuation helicopter. Casualties from the visitors exceeded those from the racers themselves during the period reported. Images Figure 1 Figure 2 Figure 4 Figure 3 Figure 5 Figure 6 Figure 7 Figure 8 PMID:8457818

  12. Valproate causes metabolic disturbance in normal man.

    PubMed Central

    Turnbull, D M; Dick, D J; Wilson, L; Sherratt, H S; Alberti, K G

    1986-01-01

    Valproate is an important anticonvulsant which is rarely associated with fatal hepatotoxicity. Previous experiments have shown that valproate inhibits several metabolic processes in isolated rat hepatocytes and when administered to starved rats causes a fall in the blood concentrations of glucose and ketone bodies. Since these changes may be related to the hepatotoxicity, the effect of valproate administration on intermediary metabolism in man was studied. One gram of valproate given orally to fasted normal humans caused a 78% fall in the concentration of 3-hydroxybutyrate and a 60% fall in total ketones. Also the concentrations of lactate, pyruvate, alanine and glycerol increased after valproate administration. Similar changes were observed after intravenous administration of 400 mg of valproate. Valproate clearly has a significant effect on intermediary metabolism in the liver and this is probably related to the mechanism of the hepatotoxicity. PMID:3084712

  13. Hydrocortisone and ACTH levels in manned spaceflight

    NASA Technical Reports Server (NTRS)

    Leach, C. S.; Campbell, B. O.

    1974-01-01

    The plasma hydrocortisone, plasma ACTH, and urinary hydrocortisone values were recorded for each man of the crews of Apollo flights eight through fifteen, 30, 14, and 5 days before flight, immediately after spaceflight recovery, and on future days until the return of most variables to preflight values. The plasma and urinary preflight hydrocortisone values were significantly higher than the postflight values. This result is discussed in terms of three possible explanations: (1) the adrenal-cortical function is suppressed during spaceflight; (2) the activity in flight may amount to stressful exercise, which tests have shown can cause a decrease in plasma adrenocortical hormones; and (3) the in-flight work-rest cycles may be such as to affect the circadian periodicity of the pituitary-adrenal function.

  14. Manned remote work station development article

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The two prime objectives of the Manned Remote Work Station (MRWS) Development Article Study are to first, evaluate the MRWS flight article roles and associated design concepts for fundamental requirements and embody key technology developments into a simulation program; and to provide detail manufacturing drawings and schedules for a simulator development test article. An approach is outlined which establishes flight article requirements based on past studies of Solar Power Satellite, orbital construction support equipments, construction bases and near term shuttle operations. Simulation objectives are established for those technology issues that can best be addressed on a simulator. Concepts for full-scale and sub-scale simulators are then studied to establish an overall approach to studying MRWS requirements. Emphasis then shifts to design and specification of a full-scale development test article.

  15. The pilot's role in manned space flight

    NASA Technical Reports Server (NTRS)

    North, W. J.

    1982-01-01

    The present investigation regarding the pilot's role in manned space flight takes into account space missions conducted with the Mercury capsule, Gemini, Apollo, Skylab, and the Shuttle. It is concluded that advancements in digital systems and automation technology have made many of the space pilot's tasks easier. However, these advancements have also made the space pilot's training more complicated. He must be familiar with the interrelated failure effects in highly complex vehicle systems. The nominal performance of the Shuttle fly-by-wire entry control system depends, for instance, on nominal electrical power from three fuel cells, nominal performance of three hydraulic auxiliary power units, five computers, other equipment, and microwave landing systems. The pilot must monitor and manage failures in these systems, and, in addition, must be prepared to intervene if an abort situation creates off-nominal conditions.

  16. The effects of noise on man

    SciTech Connect

    Kryter, K.D.

    1985-01-01

    As a reference source of research concerning effects of noise on people, this book reports and analyzes procedures used in regulation and control of noise. Quantitative relations are formed between physical measures of environmental noise and the reactions of people and communities to noise. The author reviews scientific and engineering research published from 1970 to the present. The Effects of Noise on Man, Second Edition discusses: adverse effects of noise and noise-induced hearing loss on speech communications; damage to hearing from ''everyday'' noise; damage to hearing from industrial noise and gunfire; work performance in noise; effects of noise on non-auditory systems of the body and sleep; aircraft and street traffic noise and its effects on health, annoyance, and house depreciation; physical measurements used for the assessment and control of environmental noise; federal standards and guidelines for community noise and proposed modification based on recent research findings.

  17. Design challenges for tomorrow's manned launch systems

    NASA Astrophysics Data System (ADS)

    Rowell, Lawrence F.

    1993-02-01

    This paper attempts to capture some of the technical and national challenges facing the design of America's next manned launch system (MLS). There are three basic paths for pursuing tomorrow's MLS; each with variations. Some characteristics that will be sought regardless of the concept selected include low development (or front-end) and life-cycle costs, safety, operability, availability, and a host of other 'ilities'. In order to discriminate among the concepts, a robust design environment and a variety of new and improved analysis tools are needed that produce critical metrics in a timely, efficient manner from a large study space. This paper presents some of the challenges in development, integration, and application of optimization, costing, operations modeling, and several engineering disciplinary tools including geometry modeling, structures, aerodynamics/aeroheating, and trajectory/performance.

  18. The Proteus syndrome: the Elephant Man diagnosed.

    PubMed Central

    Tibbles, J A; Cohen, M M

    1986-01-01

    Sir Frederick Treves first showed Joseph Merrick, the famous Elephant Man, to the Pathological Society of London in 1884. A diagnosis of neurofibromatosis was suggested in 1909 and was widely accepted. There is no evidence, however, of café au lait spots or histological proof of neurofibromas. It is also clear that Joseph Merrick's manifestations were much more bizarre than those commonly seen in neurofibromatosis. Evidence indicates that Merrick suffered from the Proteus syndrome and had the following features compatible with this diagnosis: macrocephaly; hyperostosis of the skull; hypertrophy of long bones; and thickened skin and subcutaneous tissues, particularly of the hands and feet, including plantar hyperplasia, lipomas, and other unspecified subcutaneous masses. Images FIG 1 FIG 2 FIG 3 FIG 4 PMID:3092979

  19. Quetelet, the average man and medical knowledge.

    PubMed

    Caponi, Sandra

    2013-01-01

    Using two books by Adolphe Quetelet, I analyze his theory of the 'average man', which associates biological and social normality with the frequency with which certain characteristics appear in a population. The books are Sur l'homme et le développement de ses facultés and Du systeme social et des lois qui le régissent. Both reveal that Quetelet's ideas are permeated by explanatory strategies drawn from physics and astronomy, and also by discursive strategies drawn from theology and religion. The stability of the mean as opposed to the dispersion of individual characteristics and events provided the basis for the use of statistics in social sciences and medicine. PMID:23970171

  20. Boscovich: scientist and man of letters

    NASA Astrophysics Data System (ADS)

    Proverbio, E.

    Ruggiero Giuseppe Boscovich (1711-1781) is known as one of the most important scientists of the second half of XVIII century, but he was active also as a man of letters, especially through an abundant production of poems in Latin verse. We try to interpret these two, apparently antinomic, aspects of his character in the framework of the culture of his epoch, in which science and literary productions were not considered as two separate or opposite fields, but only two different aspects of human knowledge. In particular we review the field of his poetic production in which this fundamental unity of knowledge is most evident, namely his poems with didactic-scientific subjects, which are examples of high-level popularization of the latest progresses in science (in particular astronomy and Newtonian physics) by means of elegant Latin verse.

  1. Rover technology for manned Mars missions

    NASA Technical Reports Server (NTRS)

    Klein, Gail

    1986-01-01

    A set of roving vehicle design requirements were postulated, corresponding to an idealized Mars transport vehicle operational scenario which could serve as a reference for a manned Mars mission. The ability of conventional vehicles to satisfy these requirements were examined. The study indicated that no conventional vehicle could satisfy all of the requirements, as the vehicles are presently configured. Consequently, the requirements have to either be relaxed and/or an alternative, less conventional vehicle design will have to be developed. A possible unconventional vehicle design which has received considerable attention for DARPA and the Army is the walker vehicle. The design issues associated with this vehicle are presented, along with a comparison of the performance capabilities of this technology vs. conventional vehicle technology.

  2. Human impact: man's role in environmental change

    SciTech Connect

    Goudie, A.

    1982-01-01

    Drawing upon worldwide examples, the author traces mankind's interaction with nature and examines human interference with environmental systems at various stages of social development. Succeeding chapters take up man's specific impact on vegetation, animals, the soil, the waters, landforms, climate, and the atmosphere. With the aid of maps, diagrams, and graphs, the book analyzes the causes and consequences of environmental changes associated with such large-scale events as agricultural expansion, domestication, deforestation, and urbanization, including the spread of salination, extinction, erosion, and pollution. Interrelations, often dynamic and unpredictable, between these phenomena make it difficult to isolate the causes of changes and to determine the resiliency of natural systems to change. 505 references, 82 figures, 97 tables.

  3. Values and the quantum conception of man

    SciTech Connect

    Stapp, H.P.

    1995-06-01

    Classical mechanics is based upon a mechanical picture of nature that is fundamentally incorrect. It has been replaced at the basic level by a radically different theory: quantum mechanics. This change entails an enormous shift in one`s basic conception of nature, one that can profoundly alter the scientific image of man himself. Self-image is the foundation of values, and the replacement of the mechanistic self-image derived from classical mechanics by one concordant with quantum mechanics may provide the foundation of a moral order better suited to today`s times, a self-image that endows human life with meaning, responsibility, and a deeper linkage to nature as a whole.

  4. Vestibular ataxia and its measurement in man

    NASA Technical Reports Server (NTRS)

    Fregly, A. R.

    1974-01-01

    Methods involved in and results obtained with a new comprehensive ataxia test battery are described, and definitions of spontaneous and induced vestibular ataxia in man are given in terms of these findings. In addition, the topic of alcohol-induced ataxia in relation to labyrinth function is investigated. Items in the test battery comprise a sharpened Romberg test, in which the subject stands on the floor with eyes closed and arms folded against his chest, feet heel-to-toe, for 60 seconds; an eyes-open walking test; an eyes-open standing test; an eyes-closed standing test; an eyes-closed on-leg standing test; an eyes-closed walk a line test; an eyes-closed heel-to-toe walking test; and supplementary ataxia tests such as the classical Romberg test.

  5. Space radiation concerns for manned exploration.

    PubMed

    Stanford, M; Jones, J A

    1999-07-01

    Spaceflight exposes astronaut crews to natural ionizing radiation. To date, exposures in manned spaceflight have been well below the career limits recommended to NASA by the National Council of Radiation Protection and Measurements (NCRP). This will not be the case for long-duration exploratory class missions. Additionally. International Space Station (ISS) crews will receive higher doses than earlier flight crews. Uncertainties in our understanding of long-term bioeffects, as well as updated analyses of the Hiroshima. Nagasaki and Chernobyl tumorigenesis data, have prompted the NCRP to recommend further reductions by 30-50% for career dose limit guidelines. Intelligent spacecraft design and material selection can provide a shielding strategy capable of maintaining crew exposures within recommended guidelines. Current studies on newer radioprotectant compounds may find combinations of agents which further diminish the risk of radiation-induced bioeffects to the crew. PMID:11542526

  6. Earth orbital operations supporting manned interplanetary missions

    NASA Astrophysics Data System (ADS)

    Sherwood, Brent; Buddington, Patricia A.; Whittaker, William L.

    The orbital operations required to accumulate, assemble, test, verify, maintain, and launch complex manned space systems on interplanetary missions from earth orbit are as vital as the flight hardware itself. Vast numbers of orbital crew are neither necessary nor desirable for accomplishing the required tasks. A suite of robotic techniques under human supervisory control, relying on sensors, software and manipulators either currently emergent or already applied in terrestrial settings, can make the job tractable. The mission vehicle becomes largely self-assembling, using its own rigid aerobrake as a work platform. The Space Station, having been used as a laboratory testbed and to house an assembly crew of four, is not dominated by the process. A feasible development schedule, if begun soon, could emplace orbital support technologies for exploration missions in time for a 2004 first interplanetary launch.

  7. Man's role in space exploration and exploitation

    NASA Technical Reports Server (NTRS)

    Loftus, Joseph P.

    1987-01-01

    The crew workloads on the Space Shuttle are described. The Space Shuttle is designed to minimize the activity of the crew in maintaining and operating the Shuttle in order for the crew to be involved in productive activities. The changing role of the crew due to the use of more automated systems on spacecraft is examined. The Shuttle flight system is dependent on embedded software, and the crew is to manage and support these systems. The primary functions of the Space Station are as a laboratory and for construction and assembly of systems, requiring EVA. Examples of EVA are presented. The correlation between manned and unmanned systems and the future direction of space research are discussed.

  8. Trauma on the Isle of Man.

    PubMed

    Hackney, R G; Varley, G; Stevens, D; Green, A

    1993-03-01

    The Isle of Man Tourist Trophy motorcycle races remain one of the most popular venues for motorcycle races. This is despite the reduced status of the event. The reason for the loss of world championship and formula one status is the nature of the road racing circuit itself. The twisting narrow roads are only closed to the public at certain times during the practice and race weeks. Motorcycling visitors to the event attempt to emulate their heroes on machines capable of high speeds. Casualties from both visitors and racers are dealt with efficiently by an expanded medical service. This includes the use of an aeromedical evacuation helicopter. Casualties from the visitors exceeded those from the racers themselves during the period reported. PMID:8457818

  9. Evidence of Extrapancreatic Glucagon Secretion in Man.

    PubMed

    Lund, Asger; Bagger, Jonatan I; Wewer Albrechtsen, Nicolai J; Christensen, Mikkel; Grøndahl, Magnus; Hartmann, Bolette; Mathiesen, Elisabeth R; Hansen, Carsten P; Storkholm, Jan H; van Hall, Gerrit; Rehfeld, Jens F; Hornburg, Daniel; Meissner, Felix; Mann, Matthias; Larsen, Steen; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K

    2016-03-01

    Glucagon is believed to be a pancreas-specific hormone, and hyperglucagonemia has been shown to contribute significantly to the hyperglycemic state of patients with diabetes. This hyperglucagonemia has been thought to arise from α-cell insensitivity to suppressive effects of glucose and insulin combined with reduced insulin secretion. We hypothesized that postabsorptive hyperglucagonemia represents a gut-dependent phenomenon and subjected 10 totally pancreatectomized patients and 10 healthy control subjects to a 75-g oral glucose tolerance test and a corresponding isoglycemic intravenous glucose infusion. We applied novel analytical methods of plasma glucagon (sandwich ELISA and mass spectrometry-based proteomics) and show that 29-amino acid glucagon circulates in patients without a pancreas and that glucose stimulation of the gastrointestinal tract elicits significant hyperglucagonemia in these patients. These findings emphasize the existence of extrapancreatic glucagon (perhaps originating from the gut) in man and suggest that it may play a role in diabetes secondary to total pancreatectomy. PMID:26672094

  10. Immunodeficiency following neonatal thymectomy in man.

    PubMed Central

    Brearley, S; Gentle, T A; Baynham, M I; Roberts, K D; Abrams, L D; Thompson, R A

    1987-01-01

    Patients undergoing cardiac bypass operations normally have a thymectomy to facilitate cannulation of the great vessels. Laboratory indices of immune function were measured in 18 children aged 9 months to 3 years who had had a thymectomy when aged 3 months or less, and in two groups of controls individually matched for age and age at operation. Total lymphocyte numbers were similar in all three groups but thymectomized children had significantly lower numbers of T cells and T cell sub-sets than controls and showed diminished responses to phytohaemagglutinin and concanavalin A. Children who have had a thymectomy early in life represent an important group in the study of the development of the immune system in man. Although the clinical consequences of early thymectomy are unclear, evidence of impairment of parameters of immunity have been found in later infancy and routine thymectomy in paediatric cardiac surgery should be avoided. PMID:3427824

  11. Maintenance of white adipose tissue in man.

    PubMed

    Hyvönen, Mervi T; Spalding, Kirsty L

    2014-11-01

    Obesity is increasing in an epidemic manner in most countries and constitutes a public health problem by enhancing the risk for diseases such as diabetes, fatty liver disease and atherosclerosis. Together these diseases form a cluster referred to as the metabolic syndrome. Despite the negative health consequences associated with excess adipose tissue, very little is known about the origin and maintenance of white adipose tissue in man. In this review we discuss what is known about the turnover of adult human adipocytes and their precursors, as well as adipose tissue heterogeneity, plasticity and developmental origins. The focus of this review is human tissue, however in many cases human data are missing and are inferred from animal studies. As such, reference to animal studies are made where human data is not available. This article is part of a directed issue entitled: Regenerative Medicine: the challenge of translation. PMID:25240584

  12. Calysto: Risk Management for Commercial Manned Spaceflight

    NASA Technical Reports Server (NTRS)

    Dillaman, Gary

    2012-01-01

    The Calysto: Risk Management for Commercial Manned Spaceflight study analyzes risk management in large enterprises and how to effectively communicate risks across organizations. The Calysto Risk Management tool developed by NASA's Kennedy Space Center's SharePoint team is used and referenced throughout the study. Calysto is a web-base tool built on Microsoft's SharePoint platform. The risk management process at NASA is examined and incorporated in the study. Using risk management standards from industry and specific organizations at the Kennedy Space Center, three methods of communicating and elevating risk are examined. Each method describes details of the effectiveness and plausibility of using the method in the Calysto Risk Management Tool. At the end of the study suggestions are made for future renditions of Calysto.

  13. Space radiation concerns for manned exploration

    NASA Astrophysics Data System (ADS)

    Stanford, Michael; Jones, Jeffrey A.

    1999-09-01

    Spaceflight exposes astronaut crews to natural ionizing radiation. To date, exposures in manned spaceflight have been well below the career limits recommended to NASA by the National Council of Radiation Protection and Measurements (NCRP). This will not be the case for long-duration exploratory class missions. Additionally, International Space Station (ISS) crews will receive higher doses than earlier flight crews. Uncertainties in our understanding of long-term bioeffects, as well as updated analyses of the Hiroshima, Nagasaki and Chernobyl tumorigenesis data, have prompted the NCRP to recommend further reductions by 30-50% for career dose limit guidelines. Intelligent spacecraft design and material selection can provide a shielding strategy capable of maintaining crew exposures within recommended guidelines. Current studies on newer radioprotectant compounds may find combinations of agents which further diminish the risk of radiation-induced bioeffects to the crew.

  14. Earth to Mars - Scenarios for early manned missions

    NASA Technical Reports Server (NTRS)

    Snoddy, William C.

    1988-01-01

    Trajectories and mission types for a manned mission to Mars are reviewed, focusing on what can be undertaken relative to available technologies. The objectives of a manned mission are outlined and several mission scenarios are described. Space Station involvement, an interplanetary manned Mars space vehicle, and the role of artificial gravity are discussed. Possible launch vehicles, surface systems options, and space vehicle configurations are examined.

  15. Water-propellant resistojets for man-tended platforms

    NASA Technical Reports Server (NTRS)

    Louviere, Allen J.; Jones, Robert E.; Morren, W. Earl; Sovey, James S.

    1987-01-01

    The selection of a propulsion system for a man-tended platform has been influenced by the planned use of resistojets for drag make-up on the manned Space Station. For that application a resistojet has been designed that is capable of operation with a wide variety of propellants, including water. The reasons for the selection of water as the propellant and the performance of water as a propellant are discussed. The man-tended platform and its mission requirements are described.

  16. Water-propellant resistojets for man-tended platforms

    NASA Technical Reports Server (NTRS)

    Louviere, Allen J.; Jones, Robert E.; Morren, W. Earl; Sovey, James S.

    1987-01-01

    The selection of a propulsion system for a man-tended platform has been influenced by the planned use of resistojets for drag make-up on the manned space station. For that application a resistojet has been designed that is capable of operation with a wide variety of propellants, including water. The reasons for the selection of water as the propellant and the performance of water as a propellant are discussed. The man-tended platform and its mission requirements are described.

  17. MAN1B1 Deficiency: An Unexpected CDG-II

    PubMed Central

    Millón, María B.; Race, Valérie; Sturiale, Luisa; Garozzo, Domenico; Mills, Philippa; Clayton, Peter; Asteggiano, Carla G.; Quelhas, Dulce; Cansu, Ali; Martins, Esmeralda; Nassogne, Marie-Cécile; Gonçalves-Rocha, Miguel; Topaloglu, Haluk; Jaeken, Jaak; Foulquier, François; Matthijs, Gert

    2013-01-01

    Congenital disorders of glycosylation (CDG) are a group of rare metabolic diseases, due to impaired protein and lipid glycosylation. In the present study, exome sequencing was used to identify MAN1B1 as the culprit gene in an unsolved CDG-II patient. Subsequently, 6 additional cases with MAN1B1-CDG were found. All individuals presented slight facial dysmorphism, psychomotor retardation and truncal obesity. Generally, MAN1B1 is believed to be an ER resident alpha-1,2-mannosidase acting as a key factor in glycoprotein quality control by targeting misfolded proteins for ER-associated degradation (ERAD). However, recent studies indicated a Golgi localization of the endogenous MAN1B1, suggesting a more complex role for MAN1B1 in quality control. We were able to confirm that MAN1B1 is indeed localized to the Golgi complex instead of the ER. Furthermore, we observed an altered Golgi morphology in all patients' cells, with marked dilatation and fragmentation. We hypothesize that part of the phenotype is associated to this Golgi disruption. In conclusion, we linked mutations in MAN1B1 to a Golgi glycosylation disorder. Additionally, our results support the recent findings on MAN1B1 localization. However, more work is needed to pinpoint the exact function of MAN1B1 in glycoprotein quality control, and to understand the pathophysiology of its deficiency. PMID:24348268

  18. 2. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, March 23, 1934. FRONT VIEW. - SOUTHWEST - Summerfield College, Music Building, Main & College Streets, Summerfield, Dallas County, AL

  19. 1. Historic American Buildings Survey W. N. Manning, Photographer, Feb. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, Feb. 3, 1934. FRONT VIEW. - SOUTH ELEVATION - Summerfield College, Music Building, Main & College Streets, Summerfield, Dallas County, AL

  20. 7. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey W. N. Manning, Photographer, January 5, 1935 VIEW SHOWING INNER CONSTRUCTION OF BRIDGE - Covered Bridge, Spanning Choccolocco Creek , Old Eastaboga, Talladega County, AL

  1. 2. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, January 5, 1935 VIEW SHOWING UNDER CONSTRUCTION OF BRIDGE - Covered Bridge, Spanning Choccolocco Creek , Old Eastaboga, Talladega County, AL

  2. 2. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, March 23, 1934. Fireplace and Mantel (Second Floor) - Boys' Methodist College, Centenary & Main Streets, Summerfield, Dallas County, AL

  3. 3. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, April 7, 1934. TELESCOPE IN OBSERVATORY. - University of Alabama, Observatory, Stadium Drive & Fifth Street, Tuscaloosa, Tuscaloosa County, AL

  4. 6. Historic American Buildings Survey W. N. Manning, Photographer. Feb. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey W. N. Manning, Photographer. Feb. 27, 1934. AUDITORIUM (TOWARD ALTAR) - Government Street Presbyterian Church, Government & Jackson Streets, Mobile, Mobile County, AL

  5. 2. Historic American Buildings Survey W. N. Manning, Photographer. Feb. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer. Feb. 27, 1934. FRONT ELEVATION - SOUTH AND EAST - Government Street Presbyterian Church, Government & Jackson Streets, Mobile, Mobile County, AL

  6. 1. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. GENERAL FRONT VIEW. - EAST ELEVATION - Oliver-Housman House, Wilkerson & Montgomery Streets, Montgomery, Montgomery County, AL

  7. Retrospective, Demographic, and Clinical Investigation of the Causes of Postoperative Infection in Patients With Lumbar Spinal Stenosis Who Underwent Posterior Stabilization

    PubMed Central

    Yaldiz, Can; Yaldiz, Mahizer; Ceylan, Nehir; Kacira, Ozlem Kitiki; Ceylan, Davut; Kacira, Tibet; Kizilcay, Gokhan; Tanriverdi, Taner

    2015-01-01

    Abstract Owing to the increasing population of elderly patients, a large number of patients with degenerative spondylosis are currently being surgically treated. Although basic measures for decreasing postoperative surgical infections (PSIs) are considered, it still remains among the leading causes of morbidity and mortality. The aim of this retrospective analysis is to present possible causes leading to PSI in patients who underwent surgery for lumbar degenerative spondylosis and highlight how it can be avoided to decrease morbidity and mortality. The study included 540 patients who underwent posterior stabilization due to degenerative lumbar stenosis between January 2013 and January 2014. The data before and after surgery was retrieved from the hospital charts. Patients with degenerative lumbar stenosis who were operated upon in this study had >2 levels of laminectomy and facetectomy. For this reason, posterior stabilization was performed for all the patients included in this study. Determining the causes of postoperative infection (PI) following spinal surgeries performed with instrumentation is a struggle. Seventeen different parameters that may be related to PI were evaluated in this study. The presence of systemic diseases, unknown glove perforations, and perioperative blood transfusions were among the parameters that increased the prevalence of PI. Alternatively, prolene sutures, double-layered gloves, and the use of rifampicin Sv (RIS) decreased the incidence of PI. Although the presence of systemic diseases, unnoticed glove perforations, and perioperative blood transfusions increased PIs, prolene suture material, double-layered gloves, and the use of RIS decreased PIs. PMID:26200620

  8. The predictive value of chronic kidney disease for assessing cardiovascular events under consideration of pretest probability for coronary artery disease in patients who underwent stress myocardial perfusion imaging.

    PubMed

    Furuhashi, Tatsuhiko; Moroi, Masao; Joki, Nobuhiko; Hase, Hiroki; Masai, Hirofumi; Kunimasa, Taeko; Fukuda, Hiroshi; Sugi, Kaoru

    2013-02-01

    Pretest probability of coronary artery disease (CAD) facilitates diagnosis and risk stratification of CAD. Stress myocardial perfusion imaging (MPI) and chronic kidney disease (CKD) are established major predictors of cardiovascular events. However, the role of CKD to assess pretest probability of CAD has been unclear. This study evaluates the role of CKD to assess the predictive value of cardiovascular events under consideration of pretest probability in patients who underwent stress MPI. Patients with no history of CAD underwent stress MPI (n = 310; male = 166; age = 70; CKD = 111; low/intermediate/high pretest probability = 17/194/99) and were followed for 24 months. Cardiovascular events included cardiac death and nonfatal acute coronary syndrome. Cardiovascular events occurred in 15 of the 310 patients (4.8 %), but not in those with low pretest probability which included 2 CKD patients. In patients with intermediate to high pretest probability (n = 293), multivariate Cox regression analysis identified only CKD [hazard ratio (HR) = 4.88; P = 0.022) and summed stress score of stress MPI (HR = 1.50; P < 0.001) as independent and significant predictors of cardiovascular events. Cardiovascular events were not observed in patients with low pretest probability. In patients with intermediate to high pretest probability, CKD and stress MPI are independent predictors of cardiovascular events considering the pretest probability of CAD in patients with no history of CAD. In assessing pretest probability of CAD, CKD might be an important factor for assessing future cardiovascular prognosis. PMID:22806318

  9. The Little Man and the Cosmic Cauldron

    NASA Astrophysics Data System (ADS)

    2008-05-01

    On the occasion of the 10th anniversary of the Very Large Telescope's First Light, ESO is releasing two stunning images of different kinds of nebulae, located towards the Carina constellation. The first one, Eta Carinae, has the shape of a 'little man' and surrounds a star doomed to explode within the next 100 000 years. The second image features a much larger nebula, whose internal turmoil is created by a cluster of young, massive stars. Green Flash at Paranal ESO PR Photo 17a/08 The Homunculus (NACO/VLT) Being brighter than one million Suns, Eta Carinae is the most luminous star known in the Galaxy. It is the closest example of a luminous blue variable, the last phase in the life of a very massive star before it explodes in a fiery supernova. Eta Carinae is surrounded by an expanding bipolar cloud of dust and gas known as the Homunculus ('little man' in Latin), which astronomers believe was expelled from the star during a great outburst seen in 1843 [1]. Eta Carinae was one of the first objects to be imaged during First Light with ESO's VLT, 10 years ago. At the time, the image obtained with a test camera already showed the unique capabilities of the European flagship telescope for ground-based optical and infrared astronomy, as well as of its unique location on the mountain of Paranal. The image had a resolution of 0.38 arcseconds. The new, recently obtained image reveals even more, with a resolution a factor of 6 to 7 times better. It was obtained with the NACO near-infrared instrument on Yepun, Unit Telescope 4 of the VLT. NACO is an adaptive optics instrument, which means that it can correct for the blurring effect of the atmosphere. And looking at the image, the power of adaptive optics is clear. The image quality is as though the whole 8.2-m telescope had been launched into space [2]. When viewed through the eyepiece of a small telescope, the Homunculus may indeed resemble a little man, but the astounding NACO image clearly shows a bipolar structure. Also

  10. Manned in Situ Confirmation of Lunar Ice

    NASA Astrophysics Data System (ADS)

    Gerené, S. P. B.; Hummeling, R. W. J.; Ockels, W. J.

    A study is performed to investigate the feasibility of a manned expedition to the Moon using the European Ariane-5 launcher. The primary objective of this lunar mission is to confirm the presence of water at the South-Pole craters. It is believed that these permanently shadowed craters contain water in the form of ice. Secondary objective is to perform lunar surface science and making a first step towards a lunar outpost. Early results show that a minimum of two Ariane-5 launches is required. In this `two Ariane' scenario the first launch will bring a Lunar Landing Vehicle (LLV) into low lunar orbit. The second will launch two astronauts in a Crew Transfer Vehicle into a rendez- vous trajectory with the LLV. Arrived at the Moon, the astronauts will enter the LLV, undock from the CTV and land at the designated site located near the rim of the South-Pole Shackleton crater. The transfer strategy for both spacecraft will be the so-called direct transfer, taking about four days. At arrival the LLV will start mapping the landing site at a ground resolution of one meter. As a consequence of the polar orbit, the CTV has to arrive fourteen days later and surface operations can take about twelve days, accumulating in a total mission-duration of 36 days. 32 days for the CTV and 22 days for the LLV. In case a `two Ariane' flight does not posses sufficient capabilities also a `three Ariane' scenario is developed, in which the LLV is split-up into two stages and launched separately. These two will dock at the Moon forming a descent stage and an ascent stage. The third launch will be a CTV. During surface operations, astronauts will set up a solar power unit, install the sample retrieval system and carry out surface science. Samples of the crater floor will be retrieved by means of a probe or robot guided along a cable suspended over the crater rim. Also, this paper shows the way in which European astronauts can be brought to the Moon for other future missions, like the

  11. Operational Philosophy Concerning Manned Spacecraft Cabin Leaks

    NASA Technical Reports Server (NTRS)

    DeSimpelaere, Edward

    2011-01-01

    The last thirty years have seen the Space Shuttle as the prime United States spacecraft for manned spaceflight missions. Many lessons have been learned about spacecraft design and operation throughout these years. Over the next few decades, a large increase of manned spaceflight in the commercial sector is expected. This will result in the exposure of commercial crews and passengers to many of the same risks crews of the Space Shuttle have encountered. One of the more dire situations that can be encountered is the loss of pressure in the habitable volume of the spacecraft during on orbit operations. This is referred to as a cabin leak. This paper seeks to establish a general cabin leak response philosophy with the intent of educating future spacecraft designers and operators. After establishing a relative definition for a cabin leak, the paper covers general descriptions of detection equipment, detection methods, and general operational methods for management of a cabin leak. Subsequently, all these items are addressed from the perspective of the Space Shuttle Program, as this will be of the most value to future spacecraft due to similar operating profiles. Emphasis here is placed upon why and how these methods and philosophies have evolved to meet the Space Shuttle s needs. This includes the core ideas of: considerations of maintaining higher cabin pressures vs. lower cabin pressures, the pros and cons of a system designed to feed the leak with gas from pressurized tanks vs. using pressure suits to protect against lower cabin pressures, timeline and consumables constraints, re-entry considerations with leaks of unknown origin, and the impact the International Space Station (ISS) has had to the standard Space Shuttle cabin leak response philosophy. This last item in itself includes: procedural management differences, hardware considerations, additional capabilities due to the presence of the ISS and its resource, and ISS docking/undocking considerations with a

  12. NASA Laboratory Analysis for Manned Exploration Missions

    NASA Technical Reports Server (NTRS)

    Krihak, Michael (Editor); Shaw, Tianna

    2014-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability Element under the NASA Human Research Program. ELA instrumentation is identified as an essential capability for future exploration missions to diagnose and treat evidence-based medical conditions. However, mission architecture limits the medical equipment, consumables, and procedures that will be available to treat medical conditions during human exploration missions. Allocated resources such as mass, power, volume, and crew time must be used efficiently to optimize the delivery of in-flight medical care. Although commercial instruments can provide the blood and urine based measurements required for exploration missions, these commercial-off-the-shelf devices are prohibitive for deployment in the space environment. The objective of the ELA project is to close the technology gap of current minimally invasive laboratory capabilities and analytical measurements in a manner that the mission architecture constraints impose on exploration missions. Besides micro gravity and radiation tolerances, other principal issues that generally fail to meet NASA requirements include excessive mass, volume, power and consumables, and nominal reagent shelf-life. Though manned exploration missions will not occur for nearly a decade, NASA has already taken strides towards meeting the development of ELA medical diagnostics by developing mission requirements and concepts of operations that are coupled with strategic investments and partnerships towards meeting these challenges. This paper focuses on the remote environment, its challenges, biomedical diagnostics requirements and candidate technologies that may lead to successful blood/urine chemistry and biomolecular measurements in future space exploration missions. SUMMARY The NASA Exploration Laboratory Analysis project seeks to develop capability to diagnose anticipated space exploration medical conditions on future manned missions. To achieve

  13. Manned remote work station development article, executive summary

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The mission requirements for the manned remote work station (MRWS) flight article and the manned remote work station open cherry picker development test article is defined. Considerations are given for the near, mid, and far term use of the MRWS with emphasis on its ultimate application: constructing the Solar Power Satellite.

  14. Man and SuperNature. Lecture 12, September 27, 1946

    ERIC Educational Resources Information Center

    Montessori, Maria

    2015-01-01

    "Man and SuperNature" is a lyrical chapter in the 1946 London course following the emergence of Cosmic Education in Kodaikanal, India. Montessori contrasts the adaptation required of animals for their survival to conscious human adaptation. Animals exist and adapt to nature, but man can alter nature and change the environment.…

  15. A Vernacular Republican Rhetoric: William Manning's "Key Of Libberty"

    ERIC Educational Resources Information Center

    Mercieca, Jennifer R.; Aune, James Arnt

    2005-01-01

    Our analysis of farmer and tavern-keeper William Manning's 1798 "Key of Libberty" extends the concept of American republican rhetoric to include both elite and vernacular forms. We find that the key components of Manning's vernacular republicanism are: an aggressive use of the rhetoric of critique; the demand for transparency in public argument;…

  16. User Requirements in Man-Machine Interactive Systems.

    ERIC Educational Resources Information Center

    Dave, Ashok

    The basic objective of the development of man-machine interactive systems is to design a system that will most effectively take into account the limitations and talents of both man and machine, recognizing that the human factors are, in certain aspects, diametrically opposed to those of the computer. This document briefly investigates those…

  17. 42 CFR 84.101 - Man test 5; requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Man test 5; requirements. 84.101 Section 84.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.101 Man test 5;...

  18. 42 CFR 84.102 - Man test 6; requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Man test 6; requirements. 84.102 Section 84.102 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.102 Man test 6;...

  19. 46 CFR 131.920 - Level of manning.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Level of manning. 131.920 Section 131.920 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.920 Level of manning. Each vessel must carry the personnel required by the Certificate of Inspection, as determined by the cognizant...

  20. 46 CFR 131.420 - Manning and supervision.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Manning and supervision. 131.420 Section 131.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Sufficiency and Supervision of Crew of Survival Craft § 131.420 Manning and supervision. (a) There must be enough trained persons aboard each survival...

  1. 42 CFR 84.101 - Man test 5; requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Man test 5; requirements. 84.101 Section 84.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.101 Man test 5;...

  2. 42 CFR 84.103 - Man tests; performance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man...

  3. 46 CFR 131.920 - Level of manning.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Level of manning. 131.920 Section 131.920 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.920 Level of manning. Each vessel must carry the personnel required by the Certificate of Inspection, as determined by the cognizant...

  4. 46 CFR 131.920 - Level of manning.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Level of manning. 131.920 Section 131.920 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.920 Level of manning. Each vessel must carry the personnel required by the Certificate of Inspection, as determined by the cognizant...

  5. 42 CFR 84.103 - Man tests; performance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man...

  6. 46 CFR 131.420 - Manning and supervision.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Manning and supervision. 131.420 Section 131.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Sufficiency and Supervision of Crew of Survival Craft § 131.420 Manning and supervision. (a) There must be enough trained persons aboard each survival...

  7. 42 CFR 84.103 - Man tests; performance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man...

  8. 46 CFR 131.920 - Level of manning.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Level of manning. 131.920 Section 131.920 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.920 Level of manning. Each vessel must carry the personnel required by the Certificate of Inspection, as determined by the cognizant...

  9. 46 CFR 169.819 - Manning of lifeboats and liferafts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Manning of lifeboats and liferafts. 169.819 Section 169.819 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Operations § 169.819 Manning of lifeboats and liferafts. (a) The provisions of this section shall apply to all vessels equipped...

  10. 46 CFR 169.819 - Manning of lifeboats and liferafts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Manning of lifeboats and liferafts. 169.819 Section 169.819 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Operations § 169.819 Manning of lifeboats and liferafts. (a) The provisions of this section shall apply to all vessels equipped...

  11. 46 CFR 169.819 - Manning of lifeboats and liferafts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Manning of lifeboats and liferafts. 169.819 Section 169.819 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Operations § 169.819 Manning of lifeboats and liferafts. (a) The provisions of this section shall apply to all vessels equipped...

  12. 46 CFR 169.819 - Manning of lifeboats and liferafts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Manning of lifeboats and liferafts. 169.819 Section 169.819 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Operations § 169.819 Manning of lifeboats and liferafts. (a) The provisions of this section shall apply to all vessels equipped...

  13. 42 CFR 84.103 - Man tests; performance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man...

  14. 77 FR 21555 - Manning, Richard W.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Manning, Richard W.; Notice of Filing Take notice that on April 2, 2012, Richard W. Manning submitted for filing, an application for authority to hold interlocking positions, pursuant to section 305(b) of the...

  15. 46 CFR 131.420 - Manning and supervision.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Manning and supervision. 131.420 Section 131.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Sufficiency and Supervision of Crew of Survival Craft § 131.420 Manning and supervision. (a) There must be enough trained persons aboard each survival...

  16. 42 CFR 84.101 - Man test 5; requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Man test 5; requirements. 84.101 Section 84.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.101 Man test 5;...

  17. 42 CFR 84.102 - Man test 6; requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man test 6; requirements. 84.102 Section 84.102 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.102 Man test 6;...

  18. 42 CFR 84.102 - Man test 6; requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Man test 6; requirements. 84.102 Section 84.102 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.102 Man test 6;...

  19. 46 CFR 131.920 - Level of manning.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Level of manning. 131.920 Section 131.920 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Miscellaneous § 131.920 Level of manning. Each vessel must carry the personnel required by the Certificate of Inspection, as determined by the cognizant...

  20. 46 CFR 169.819 - Manning of lifeboats and liferafts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Manning of lifeboats and liferafts. 169.819 Section 169.819 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Operations § 169.819 Manning of lifeboats and liferafts. (a) The provisions of this section shall apply to all vessels equipped...

  1. 42 CFR 84.103 - Man tests; performance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Man tests; performance requirements. 84.103 Section 84.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.103 Man...

  2. 42 CFR 84.101 - Man test 5; requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Man test 5; requirements. 84.101 Section 84.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.101 Man test 5;...

  3. 42 CFR 84.102 - Man test 6; requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Man test 6; requirements. 84.102 Section 84.102 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.102 Man test 6;...

  4. 46 CFR 131.420 - Manning and supervision.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Manning and supervision. 131.420 Section 131.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Sufficiency and Supervision of Crew of Survival Craft § 131.420 Manning and supervision. (a) There must be enough trained persons aboard each survival...

  5. 42 CFR 84.101 - Man test 5; requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man test 5; requirements. 84.101 Section 84.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.101 Man test 5;...

  6. A Man: An Autoethnographic Analysis of Black Male Identity Negotiation

    ERIC Educational Resources Information Center

    Waymer, Damion

    2008-01-01

    "A Man" is an original text created by the author that deals with the struggles that Black men experience when confronted by White privilege. By using autoethnographic analysis, the author critiques the language, ironies, tensions, emotions, and opportunities expressed within "A Man," then extends findings to confront the issues that Black men…

  7. 46 CFR 131.420 - Manning and supervision.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Manning and supervision. 131.420 Section 131.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Sufficiency and Supervision of Crew of Survival Craft § 131.420 Manning and supervision. (a) There must be enough trained persons aboard each survival...

  8. 42 CFR 84.102 - Man test 6; requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Man test 6; requirements. 84.102 Section 84.102 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.102 Man test 6;...

  9. Lowest cost, nearest term options for a manned Mars mission

    NASA Astrophysics Data System (ADS)

    Sauls, Bob; Mortensen, Michael; Myers, Renee; Guacci, Giovanni; Montes, Fred

    This study is part of a NASA/USRA Advanced Design Program project executed for the purpose of examining the requirements of a first manned Mars mission. The mission, classified as a split/sprint mission, has been designed for a crew of six with a total manned trip time of one year.

  10. Man: A Course of Study. Occasional Paper No. 3.

    ERIC Educational Resources Information Center

    Bruner, Jerome S.

    Written in 1965, the author describes the initial stages in the development of the elementary level curriculum, Man: A Course of Study. The structure and form of the course and three pedagogical techniques are discussed. The course is organized around the humanizing forces of tool-making, language, social organization, the management of man's…

  11. Sexual Harassment and Manly Sports: Are They Related?

    ERIC Educational Resources Information Center

    Murolo, Nancy Maurer; Schmelkin, Liora Pedhazur

    This study investigates the relationship between sexual harassment and participation in "manly" sports (i.e., football, baseball, basketball, soccer, and wrestling) at the high school level. Manly sports are defined as those sports that celebrate values of dominance, aggression, male solidarity, and female exclusion. Participants were 353 11th-…

  12. Lowest cost, nearest term options for a manned Mars mission

    NASA Technical Reports Server (NTRS)

    Sauls, Bob; Mortensen, Michael; Myers, Renee; Guacci, Giovanni; Montes, Fred

    1992-01-01

    This study is part of a NASA/USRA Advanced Design Program project executed for the purpose of examining the requirements of a first manned Mars mission. The mission, classified as a split/sprint mission, has been designed for a crew of six with a total manned trip time of one year.

  13. Natural Disasters: Acts of God or Acts of Man?

    ERIC Educational Resources Information Center

    Wijkman, Anders; Timberlake, Lloyd

    This eight-chapter publication considers the man-made and natural causes of natural disasters. Following an introduction, Chapter 1 outlines the increase in natural disasters in the past decade and discusses the ratio of disasters from one continent to another. Chapter 2 discusses man-made factors such as deforestation and overused soil in causing…

  14. Spacecraft Power Systems Engineering: Solutions for NASA's Manned Space Program

    NASA Technical Reports Server (NTRS)

    Scott, John H.

    2007-01-01

    An overview of spacecraft power systems is presented, with a focus on applications in the manned space program. The topics include: 1) History; 2) State-of-the-art; 3) Development directions; 4) Focus on applications in the manned space program led from JSC; 5) Power Systems Engineering Trade Space; 6) Power Generation and Energy Storage; 7) Power Distribution and Control; and 8) Actuation

  15. Integration effects of underwing forward- and rearward-mounted separate-flow, flow-through nacelles on a high-wing transport

    NASA Technical Reports Server (NTRS)

    Lamb, M.; Abeyounis, W. K.

    1986-01-01

    An experimental investigation was conducted in the Langley 16-Foot Transonic Tunnel at free-stream Mach numbers from 0.70 to 0.82 and angles of attack from -2.5 to 4.0 degrees to determine the integration effects of pylon-mounted underwing forward and rearward separate-flow, flow-through nacelles on a high-wing transonic transport configuration. The results showed that the installed drag of the nacelle/pylon in the rearward location was slightly less than that of the nacelle/pylon in the forward location. This reduction was due to the reduction in calculated skin friction of the nacelle/pylon configuration. In all cases the combined value of form, wave, and interference drag was excessively high. However, the configuration with the nacelle/pylon in a rearward location produced an increase in lift over that of the basic wing-body configuration.

  16. [A Case of Virchow's Lymph Node Recurrence of Gastric Cancer Who Had Underwent Gastrectomy, and Treated with S-1 Monotherapy Leading to Complete Response (CR)].

    PubMed

    Tanaka, Shinichi; Sanefuji, Kensaku; Kabashima, Akira; Maekawa, Souichirou

    2016-04-01

    We report the case of a 67-year-old male with Virchow's lymph node recurrence of gastric cancer, who underwent distal gastrectomy for type 2 forecourt part of pylorus gastric cancer, showing complete response(CR)in response to S-1 monotherapy. The tumor was pathologically diagnosed as Stage IIIb(well to poorly differentiated adenocarcinoma, T3[SE], N2 [20/51], M0). Virchow's lymph node metastasis was confirmed 2 months after surgery. One week after S-1 administration, a reduction in lymph node size was observed. After 5 courses of S-1 monotherapy, he achieved CR. The patient maintained CR for 2 years, before we switched to uracil and tegafur(UFT)monotherapy. The patient maintained CR for 2 years, after which UFT was discontinued. No relapse was observed 22 months after discontinuation. PMID:27220793

  17. Pediatric keratoconus and iontophoretic corneal crosslinking: refractive and topographic evidence in patients underwent general and topical anesthesia, 18 months of follow-up.

    PubMed

    Magli, Adriano; Chiariello Vecchio, Elisabetta; Carelli, Roberta; Piozzi, Elena; Di Landro, Felicia; Troisi, Salvatore

    2016-08-01

    To evaluate the efficiency and safety of iontophoretic transepithelial corneal crosslinking in pediatric patients with progressive keratoconus underwent general or topical anesthesia in 18 months follow-up. 13 patients (13 eyes) diagnosed with progressive keratoconus underwent corneal CXL with iontophoresis (I-CXL). Riboflavin solution was administered by iontophoresis for 5 min, and then UV-A irradiation (10 mW/cm) was performed for 9 min. Preoperative and post-operative visits at 1, 6, 12, and 18 months assessed the following parameters: uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), slit-lamp biomicroscopy, corneal topography, optical tomography, and pachymetry with Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany), endothelial biomicroscopy (Konan Specular Microscope; Konan Medical, Inc., Hyogo, Japan). The paired Student t test was used to compare data during the follow-up. 10 males and 3 females with a mean age of 15.4 ± 1.7 years (range 11-18 years) were included. The results showed a stabilization of the refractive UCVA and BCVA as early as the first post-operative month, with a slight improvement over time. The Kmax remained stable throughout follow-up (p = 0.04). Transepithelial collagen crosslinking by iontophoresis, unlike other transepithelial techniques seems to halt pediatric keratoconus progression over 18 months. This is the second study evaluating CXL with iontophoresis in pediatric patients with progressive keratoconus with 18 months of follow-up using two different ways of anesthesia. PMID:26704375

  18. Comparison of Estimations Versus Measured Oxygen Consumption at Rest in Patients With Heart Failure and Reduced Ejection Fraction Who Underwent Right-Sided Heart Catheterization.

    PubMed

    Chase, Paul J; Davis, Paul G; Wideman, Laurie; Starnes, Joseph W; Schulz, Mark R; Bensimhon, Daniel R

    2015-12-01

    Cardiac output during right-sided heart catheterization is an important variable for patient selection of advanced therapies (cardiac transplantation and left ventricular assist device implantation). The Fick method to determine cardiac output is commonly used and typically uses estimated oxygen consumption (VO2) from 1 of 3 published empirical formulas. However, these estimation equations have not been validated in patients with heart failure and reduced ejection fraction (HFrEF). The objectives of the present study were to determine the accuracy of 3 equations for estimating VO2 compared with direct measurement of VO2 and determine the extent clinically significant error occurred in calculating cardiac output of patients with HFrEF. Breath-by-breath measurements of VO2 from 44 patients who underwent cardiac catheterization (66% men; age, 65 ± 11 years, left ventricular ejection fraction, 22 ± 6%) were compared with the derived estimations of LaFarge and Miettinen, Dehmer et al, and Bergstra et al. Single-sample t tests found only the mean difference between the estimation of LaFarge and Miettinen and the measured VO2 to be nonsignificant (-10.3 ml/min ± 6.2 SE, p = 0.053). Bland-Altman plots demonstrated unacceptably large limits of agreement for all equations. The rate of ≥25% error in the equations by LaFarge and Miettinen, Dehmer et al, and Bergstra et al occurred in 11%, 23%, and 45% of patients, respectively. Misclassification of cardiac index derived from each equation for 2 clinically important classifications: cardiogenic shock-21%, 23%, and 32% and hypoperfusion-16%, 16%, and 25%; respectively. In conclusion, these findings do not support the use of these empiric formulas to estimate the VO2 at rest in patients with HFrEF who underwent right-sided heart catheterization. PMID:26443561

  19. Frequency and Effects of Excess Dosing of Anticoagulants in Patients ≤55 Years With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention (from the VIRGO Study).

    PubMed

    Gupta, Aakriti; Chui, Philip; Zhou, Shengfan; Spertus, John A; Geda, Mary; Lorenze, Nancy; Lee, Ike; D' Onofrio, Gail; Lichtman, Judith H; Alexander, Karen P; Krumholz, Harlan M; Curtis, Jeptha P

    2015-07-01

    Excess dosing of anticoagulant agents has been linked to increased risk of bleeding after percutaneous coronary intervention (PCI) for women compared with men, but these studies have largely included older patients. We sought to determine the prevalence and gender-based differences of excess dosing of anticoagulants including glycoprotein IIb/IIIa inhibitors, bivalirudin, and unfractionated heparin in young patients with acute myocardial infarction who underwent PCI and to examine its association with bleeding. Of 2,076 patients enrolled in the Variation in Recovery: Role of Gender on Outcomes of Young Acute Myocardial Infarction Patients study who underwent PCI, we abstracted doses of unfractionated heparin, bivalirudin, and glycoprotein IIb/IIIa inhibitors administered during PCI from the medical records. At least 47.2% received at least 1 excess dose of an anticoagulant, which did not differ by gender. We used logistic regression to determine the predictors of excess dosing and the association of excess dosing with bleeding. In multivariable analysis, only lower body weight and younger age were significant predictors of excess dosing. Bleeding was higher in young women who received excess dosing versus those who did not (9.3% vs 6.0%, p = 0.03) but was comparable among men (5.2% vs 5.9%, p = 0.69) in univariate analysis. In multivariable analysis, there was a trend to an association between excess dosing and bleeding (odds ratio 1.33, 95% confidence interval 0.92 to 1.91) although not statistically significant. In conclusion, approximately half of the patients received excess dosing of anticoagulant drugs during PCI, which did not vary based on gender. There was a trend toward an association between excess dosing and increased bleeding, although not statistically significant. PMID:25937348

  20. COMPARATIVE ANALYSIS ON MUSCLE STRENGTH AMONG PATIENTS WHO UNDERWENT ARTHROSCOPIC TENOTOMY OF THE LONG HEAD OF THE BICEPS IN RELATION TO ESTHETIC DEFORMITY

    PubMed Central

    Almeida, Alexandre; Valin, Márcio Rangel; de Almeida, Nayvaldo Couto; Roveda, Gilberto; Agostini, Ana Paula

    2015-01-01

    Objective: To determine whether there was any discrepancy in elbow flexion strength among patients with and without evident clinical deformity resulting from arthroscopic tenotomy on the long head of the biceps. Method: A group of 120 patients who underwent this procedure were evaluated. After applying the exclusion criteria, 89 patients remained in the analysis. Eighteen months after the operation (median), the elbow flexion strength was measured in newtons using a digital dynamometer. Three consecutive measurements were made and the average was used. The dominant and non-dominant sides were compared. Sex, age and mean elbow flexion strength in the operated and contralateral arms of patients with and without apparent clinical deformity were evaluated. Results: The median elbow flexion strength among the patients with evident clinical deformity was 17.78 N for the dominant arm and 20.87 N for the non-dominant arm. The difference was 2.51 N. In the group without evident clinical deformity, the difference was 2.14 N. The median muscle strength in the operated arm was 17.26 N, while the median was 20.06 N in the non-operated arm, thus suggesting that there was a significant loss of muscle strength (p = 0.005). The difference in muscle strength loss between the patients with and without evident deformity was not considered statistically significant (p = 0.977). Conclusion: The patients who underwent arthroscopic tenotomy on the long head of the biceps with or without apparent clinical deformity from distal migration presented similar elbow flexion muscle strength. PMID:27047871

  1. HO-1 gene overexpression enhances the beneficial effects of superparamagnetic iron oxide labeled bone marrow stromal cells transplantation in swine hearts underwent ischemia/reperfusion: an MRI study.

    PubMed

    Jiang, Yibo; Chen, Lijuan; Tang, Yaoliang; Ma, Genshan; Shen, Chengxing; Qi, Chunmei; Zhu, Qi; Yao, Yuyu; Liu, Naifeng

    2010-05-01

    To determine the effect of intracoronary transfer of superparamagnetic iron oxide (SPIO) labeled heme oxygenase-1 (HO-1) overexpressed bone marrow stromal cells (BMSCs) in a porcine myocardial ischemia/reperfusion model. Cell apoptosis was assayed and supernatant cytokine concentrations were measured in BMSCs that underwent hypoxia/reoxygen in vitro. Female mini-swines that underwent 1 h LAD occlusion followed by 1 h reperfusion were randomly allocated to receive intracoronary saline (control), 1 x 10(7) SPIO-labeled BMSCs transfected with pcDNA3.1-Lacz plasmid (Lacz-BMSCs), pcDNA3.1-human HO-1 (HO-1-BMSCs), pcDNA3.1-hHO-1 pretreated with a HO inhibitor, tin protoporphyrin (SnPP, n = 10 each). MRI and postmortem histological analysis were made at 1 week or 3 months thereafter. Post hypoxia/reoxygen in vitro, apoptosis was significantly reduced, supernatant VEGF significantly increased while TNF-alpha and IL-6 significantly reduced in HO-1-BMSCs group compared with Lacz-BMSCs group (all p < 0.05). Myocardial expression of VEGF was significantly higher in HO-1-BMSCs than in Lacz-BMSCs group at 1 week post transplantation (all p < 0.05). Signal voids induced by the SPIO were detected in the peri-infarction region in all BMSC groups at 1 week but not at 3 months post transplantation and the extent of the hypointense signal was the highest in HO-1-BMSCs group, and histological analysis showed that signal voids represented cardiac macrophages that engulfed the SPIO-labeled BMSCs. Pretreatment with SnPP significantly attenuated the beneficial effects of HO-1-BMSCs. Transplantation of HO-1-overexpressed BMSCs significantly enhanced the beneficial effects of BMSCs on improving cardiac function in this model. PMID:20033189

  2. Modelling an infrared Man Portable Air Defence System

    NASA Astrophysics Data System (ADS)

    Birchenall, Richard P.; Richardson, Mark A.; Brian, Butters; Roy, Walmsley

    2010-09-01

    The global proliferation of shoulder launched IR Man Portable Air Defence Systems (ManPADS) has resulted in the existence of a serious threat to both civilian and military aircraft from terrorist attack. Some of the older generations of ManPADS can be defeated with modern countermeasures but even the most sophisticated protection still has vulnerabilities to the latest family of ManPADS. This paper describes the work undertaken by the authors to model a second generation ManPAD, based on the Russian SA-14, and assess the vulnerabilities of aircraft both with and without flare countermeasures from these systems. The conclusions are the results of over 11,000 simulated firings against targets of varying aspects, velocities and altitudes.

  3. Estimation of dose to man from environmental tritium

    SciTech Connect

    Rohwer, P S; Etnier, E L

    1980-01-01

    Factors important for characterization of tritium in environmental pathways leading to exposure of man are reviewed and quantification of those factors is discussed. Parameters characterizing the behavior of tritium in man are also subjected to review. Factors to be discussed include organic binding, bioaccumulation, quality factor and transmutation. A variety of models are presently in use to estimate dose to man from environmental releases of tritium. Results from four representative models are compared and discussed. Site-specific information is always preferable when parameterizing models to estimate dose to man. There may be significant differences in dose potential among geographic regions due to variable factors. An example of one such factor examined is absolute humidity. It is concluded that adequate methodologies exist for estimation of dose to man from environmental tritium although a number of areas are identified where additional tritium research is desirable.

  4. Physiological characteristics of cold acclimatization in man

    NASA Astrophysics Data System (ADS)

    Mathew, Lazar; Purkayastha, S. S.; Jayashankar, A.; Nayar, H. S.

    1981-09-01

    Studies were conducted on 15 healthy young soldiers to evaluate the effect of a cold acclimatization schedule on the thermoregulatory and metabolic activity on exposure to acute cold stress. These men were exposed to cold (10‡C) for 4 h daily wearing only shorts for 21 days, in a cold chamber. They were subjected to a standard cold test at 10 ± 1‡C the day 1, 6, 11 and 21. The subjects were made to relax in a thermoneutral room (26 28‡C) for 1 h and their heart rate, blood pressure, oxygen consumption, oral temperature, mean skin temperature, mean body temperature, peripheral temperatures, and shivering activity were recorded. Then they were exposed to 10‡C and measurements were repeated at 30 min intervals, for 2 h. The cold induced vasodilatation (CIVD), cold pressor response and thermoregulatory efficiency tests were measured initially and at the end of acclimatization schedule. The data show that the procedure resulted in elevated resting metabolism, less fall in body temperature during acute cold stress, reduction in shivering, improvement in CIVD and thermoregulatory efficiency and less rise in BP and HR during cold pressor response. The data suggest the possibility of cold acclimatization in man by repeated exposure to moderately severe cold stress.

  5. Landing Energy Dissipation for Manned Reentry Vehicles

    NASA Technical Reports Server (NTRS)

    Fisher, Lloyd J., Jr.

    1960-01-01

    Analytical and experimental investigations have been made to determine the landing-energy-dissipation characteristics for several types of landing gear for manned reentry vehicles. The landing vehicles are considered in two categories: those having essentially vertical-descent paths, the parachute-supported vehicles, and those having essentially horizontal paths, the lifting vehicles. The energy-dissipation devices discussed are crushable materials such as foamed plastics and honeycomb for internal application in couch-support systems, yielding metal elements as part of the structure of capsules or as alternates for oleos in landing-gear struts, inflatable bags, braking rockets, and shaped surfaces for water impact. It appears feasible to readily evaluate landing-gear systems for internal or external application in hard-surface or water landings by using computational procedures and free-body landing techniques with dynamic models. The systems investigated have shown very interesting energy-dissipation characteristics over a considerable range of landing parameters. Acceptable gear can be developed along lines similar to those presented if stroke requirements and human-tolerance limits are considered.

  6. Astronomy on a manned Mars mission

    NASA Technical Reports Server (NTRS)

    Burns, Jack O.

    1986-01-01

    Three extra-solar-system astronomical experiments onboard a manned Mars mission are proposed. First, a modest, 50 cm aperture optical-ultraviolet-infrared telescope (or pair used as an interferometer) coupled with the Mars-Sun baseline would increase the number (by a factor of 3.4) and a volume of stars with accurately measured distances via stellar parallax and, therefore, greatly improve upon the cosmic distance scale; the darker sky at Mars would also provide nearly a full astronomical magnitude deeper images of distant and low brightness objects (limited by zodiacal light). Second, a gamma-ray burst detector coupled with similar detectors in other parts of the solar system will be used to reduce the position error boxes and to study the nature of these energetic sources. Third, the long baselines on a Mars mission radio interferometer will provide a view of the radio universe at unprescedented resolution, 4 x 10 to the minus 9th arcsec at 1 mm wavelength, which can potentially resolve the engine in nearby active galaxies. Each of these experiments is relatively inexpensive, taking advantage of the human presence for operation and maintenance, and the long Earth to Mars baseline.

  7. Aerobrake design studies for manned Mars missions

    NASA Technical Reports Server (NTRS)

    Tauber, M.; Chargin, M.; Henline, W.; Hamm, K. R., Jr.; Miura, H.; Chiu, A.; Yang, L.

    1991-01-01

    The dimensions of aerobrakes and associated heat shields are calculated as a fraction of the vehicle mass required for a high-velocity manned Mars entry. The entry speed and deceleration limit are assumed to be 8.6 km/sec and 5 earth g, respectively, to consider vehicles with low lift-drag ratio (L/D) and ballistic coefficients of 100 and 200 kg/sq m, as well as a vehicle with a medium L/D and a ballistic coefficient of 375 kg/sq m. The aerobrake mass plus the heat shield divided by an optimized, blunt-shaped vehicle's total mass is 15 and 13 percent for ballistic coefficients of 100 and 200 kg/sq m, respectively. For a winged vehicle the mass fraction is 17 percent because the higher ballistic coefficient requires more thermal protection to account for the greater temperatures generated. It is concluded that aerobraking is more efficient than propulsive braking because the mass fraction for a propulsive system would be 4 or 5 times greater than those calculated for aerobraking.

  8. Manned interplanetary missions: prospective medical problems.

    PubMed

    Grigoriev, A I; Svetaylo, E N; Egorov, A D

    1998-12-01

    The present review aimed to suggest approaches to prospective medical problems related to the health maintenance of space crews during future manned interplanetary, particularly Martian, missions up to 2-3 years with a possible stay on a planet with gravity different from that on Earth. The approaches are based on knowledge so far obtained from our analysis of the medical support of long-term orbital flights up to one year, as well as on the consideration of specific conditions of interplanetary missions. These specific conditions include not only long-term exposure to microgravity, but also a prolonged stay of unpredictable duration (2-3 years) on board a spacecraft or on a planet without direct contact with Earth, and living in a team with a risk of psychological incompatibility and the impossibility of an urgent return to Earth. These conditions necessitate a highly trained medical person in the crew, diagnostic tools and equipment, psychophysiological support, countermeasures, as well as the means for urgent, including surgical, treatment on board a spacecraft or on a planet. In this review, the discussion was focused on the following predictable medical problems during an interplanetary mission; 1) unfavorable effects of prolonged exposure to microgravity, 2) specific problems related to Martian missions, 3) medical monitoring, 4) countermeasures, 5) psychophysiological support and 6) the medical care system. PMID:11542693

  9. Marijuana smoking and cold tolerance in man.

    PubMed

    Hanna, J M; Strauss, R H; Itagaki, B; Kwon, W J; Stanyon, R; Bindon, J; Hong, S K

    1976-06-01

    Ten men who were marijuana users served as subjects in a study of the effects of marijuana smoking on response to cold. Cold water (28 degrees C for 60 min) and cold air (20 degrees C for 120 min) mediums were utilized with three exposures in each medium. The three exposures followed smoking marijuana, smoking placebo, and a no-smoking control period. Additionally, a breathhold experiment preceded and followed the four smoking periods. Marijuana and placebo smoke were inhaled from a spirometer with each man receiving the smoke of 0.739 g of marijuana and placebo. Smoking marijuana did not greatly modify body heat content, since rectal temperature and most peripheral temperatures were not altered. However, temperatures over voluntary muscles likely to be involved in shivering were elevated. Heat production also greatly increased after marijuana, suggesting that it had stimulated shivering. Marijuana also produced tachycardia and abolished apneic bradycardia. The mechanism of this action is not clear, but some sympathetic involvement is indicated. PMID:779756

  10. Man-machine cooperation in advanced teleoperation

    NASA Technical Reports Server (NTRS)

    Fiorini, Paolo; Das, Hari; Lee, Sukhan

    1993-01-01

    Teleoperation experiments at JPL have shown that advanced features in a telerobotic system are a necessary condition for good results, but that they are not sufficient to assure consistently good performance by the operators. Two or three operators are normally used during training and experiments to maintain the desired performance. An alternative to this multi-operator control station is a man-machine interface embedding computer programs that can perform some of the operator's functions. In this paper we present our first experiments with these concepts, in which we focused on the areas of real-time task monitoring and interactive path planning. In the first case, when performing a known task, the operator has an automatic aid for setting control parameters and camera views. In the second case, an interactive path planner will rank different path alternatives so that the operator will make the correct control decision. The monitoring function has been implemented with a neural network doing the real-time task segmentation. The interactive path planner was implemented for redundant manipulators to specify arm configurations across the desired path and satisfy geometric, task, and performance constraints.

  11. When does "economic man" dominate social behavior?

    PubMed

    Camerer, Colin F; Fehr, Ernst

    2006-01-01

    The canonical model in economics considers people to be rational and self-regarding. However, much evidence challenges this view, raising the question of when "Economic Man" dominates the outcome of social interactions, and when bounded rationality or other-regarding preferences dominate. Here we show that strategic incentives are the key to answering this question. A minority of self-regarding individuals can trigger a "noncooperative" aggregate outcome if their behavior generates incentives for the majority of other-regarding individuals to mimic the minority's behavior. Likewise, a minority of other-regarding individuals can generate a "cooperative" aggregate outcome if their behavior generates incentives for a majority of self-regarding people to behave cooperatively. Similarly, in strategic games, aggregate outcomes can be either far from or close to Nash equilibrium if players with high degrees of strategic thinking mimic or erase the effects of others who do very little strategic thinking. Recently developed theories of other-regarding preferences and bounded rationality explain these findings and provide better predictions of actual aggregate behavior than does traditional economic theory. PMID:16400140

  12. Histological investigations on the Tyrolean Ice Man.

    PubMed

    Hess, M W; Klima, G; Pfaller, K; Künzel, K H; Gaber, O

    1998-08-01

    The 5,200-year-old Tyrolean Ice Man discovered in 1991 in the Otztal Alps is the world's most ancient known human glacier mummy. Histological investigation was aimed at 1) optimizing specimen preparation and 2) documenting the preservation state of (sub)cellular components. Minute pieces of frozen tissue were removed endoscopically from rib bone and cartilage, major blood vessels, oral cavity and alimentary tract, liver, spleen, diaphragm, respiratory system, femoral muscle and nerve, sympathetic trunk, brain, and skin. Double fixation with glutaraldehyde followed by osmium tetroxide and embedding in Epon/Araldite epoxy resins proved to be the method of choice for both light and transmission electron microscopy combined with classical histochemistry. In particular, mild evacuation of the desiccated tissue was determined to be essential to ensure homogeneous infiltration with fixatives and resins; as a result, sections of excellent quality could be obtained with any kind of sample. With regard to the preservation degree of (sub)cellular components, distinct tissue-specific patterns were observed. There were highly intact skeletal and connective tissues proper, however, most interestingly, there were remarkably intact nervous tissue components as well. By contrast, epithelial, muscle, and reticular connective tissues as well as blood had generally disintegrated due to autolysis, freeze/thaw damage, and adipocere formation. For a tentative interpretation of these patterns, we considered general aspects of cryopreservation, such as physicochemical properties of subcellular constituents and tissue physiology. PMID:9712480

  13. NASA Laboratory Analysis for Manned Exploration Missions

    NASA Technical Reports Server (NTRS)

    Krihak, Michael K.; Shaw, Tianna E.

    2014-01-01

    The Exploration Laboratory Analysis (ELA) project supports the Exploration Medical Capability Element under the NASA Human Research Program. ELA instrumentation is identified as an essential capability for future exploration missions to diagnose and treat evidence-based medical conditions. However, mission architecture limits the medical equipment, consumables, and procedures that will be available to treat medical conditions during human exploration missions. Allocated resources such as mass, power, volume, and crew time must be used efficiently to optimize the delivery of in-flight medical care. Although commercial instruments can provide the blood and urine based measurements required for exploration missions, these commercial-off-the-shelf devices are prohibitive for deployment in the space environment. The objective of the ELA project is to close the technology gap of current minimally invasive laboratory capabilities and analytical measurements in a manner that the mission architecture constraints impose on exploration missions. Besides micro gravity and radiation tolerances, other principal issues that generally fail to meet NASA requirements include excessive mass, volume, power and consumables, and nominal reagent shelf-life. Though manned exploration missions will not occur for nearly a decade, NASA has already taken strides towards meeting the development of ELA medical diagnostics by developing mission requirements and concepts of operations that are coupled with strategic investments and partnerships towards meeting these challenges. This paper focuses on the remote environment, its challenges, biomedical diagnostics requirements and candidate technologies that may lead to successful blood-urine chemistry and biomolecular measurements in future space exploration missions.

  14. Freezing water in no-man's land.

    PubMed

    Manka, Alexandra; Pathak, Harshad; Tanimura, Shinobu; Wölk, Judith; Strey, Reinhard; Wyslouzil, Barbara E

    2012-04-01

    We report homogeneous ice nucleation rates between 202 K and 215 K, thereby reducing the measurement gap that previously existed between 203 K and 228 K. These temperatures are significantly below the homogenous freezing limit, T(H)≈ 235 K for bulk water, and well within no-man's land. The ice nucleation rates are determined by characterizing nanodroplets with radii between 3.2 and 5.8 nm produced in a supersonic nozzle using three techniques: (1) pressure trace measurements to determine the properties of the flow as well as the temperature and velocity of the droplets, (2) small angle X-ray scattering (SAXS) to measure the size and number density of the droplets, and (3) Fourier Transform Infrared (FTIR) spectroscopy to follow the liquid to solid phase transition. Assuming that nucleation occurs throughout the droplet volume, the measured ice nucleation rates J(ice,V) are on the order of 10(23) cm(-3) s(-1), and agree well with published values near 203 K. PMID:22354018

  15. Takeru Higuchi, the man and the scientist.

    PubMed

    Barratt, Gillian; Puisieux, Francis

    2011-10-10

    Madison (United States), December 7th 1941. It is early in the morning. Takeru Higuchi is listening to the radio when the programme is suddenly interrupted: part of the American naval fleet has just been destroyed in an air-raid on Pearl Harbour. For the United States, their involvement in the World War is now inevitable. For Takeru Higuchi, the son of Japanese immigrants, this was the beginning of an inner struggle. As a student of Physical Chemistry at the University of Wisconsin, he had received a fellowship from the American government; the war between the two countries pulled him in opposing directions. His austere childhood had left him with an extremely determined character and Takeru Higuchi chose to overcome his suffering by a personal dichotomy: he gave his heart to Japan but put his trust in the United States and devoted his energy to the service of science. This choice made him a man and a scientist of exceptional qualities, producing scientific work astonishing by its originality and quantity, making a major contribution to the pharmaceutical profession, particularly in the field of research. PMID:21640808

  16. Advanced Manned Launch System (AMLS) study

    NASA Technical Reports Server (NTRS)

    Ehrlich, Carl F., Jr.; Potts, Jack; Brown, Jerry; Schell, Ken; Manley, Mary; Chen, Irving; Earhart, Richard; Urrutia, Chuck; Randolph, Ray; Morris, Jim

    1992-01-01

    To assure national leadership in space operations and exploration in the future, NASA must be able to provide cost effective and operationally efficient space transportation. Several NASA studies and the joint NASA/DoD Space Transportation Architecture Studies (STAS) have shown the need for a multi-vehicle space transportation system with designs driven by enhanced operations and low costs. NASA is currently studying an advanced manned launch system (AMLS) approach to transport crew and cargo to the Space Station Freedom. Several single and multiple stage systems from air-breathing to all-rocket concepts are being examined in a series of studies potential replacements for the Space Shuttle launch system in the 2000-2010 time frame. Rockwell International Corporation, under contract to the NASA Langley Research Center, has analyzed a two-stage all-rocket concept to determine whether this class of vehicles is appropriate for the AMLS function. The results of the pre-phase A study are discussed.

  17. Wisconsin's study of manned Mars missions

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The design group focused on three topics: (1) Extravehicular Activities, (2) Sample Return Missions, and (3) Structural and Construction Considerations of a Manned Mars Habitat. Extravehicular Activities permit a Mars based astronaut to exit the habitat and perform mission activities in the harsh Mars environment. Today's spacesuit gloves are bulky, hard to manipulate and fatiguing. A mechanical assistance mechanism has been developed for the glove that will reduce user fatigue and increase the duration of EVA's. Oxygen supply systems are also being developed for the EVA astronaut. A scuba type system of tanked breathing air proves to be the most efficient system for short duration EVA's. A system that extracts the oxygen from atmospheric carbon dioxide can provide oxygen for long duration FVA's. Sample Return Missions require that samples be taken from several sites. Transportation considerations are addressed and two transportation schemes are proposed. The first scheme involves a lighter than air balloon. This system provides excellent range. The second design is a rover that uses tracks rather than wheels. Track rovers perform well in soft, sandy conditions. Engineering aspects of a habitat and domed greenhouse were investigated and plans for the habitat have been made. A configuration has been established and construction details have been made.

  18. Soils: man-caused radioactivity and radiation forecast

    SciTech Connect

    Gablin, Vassily

    2007-07-01

    Available in abstract form only. Full text of publication follows: One of the main tasks of the radiation safety guarantee is non-admission of the excess over critical radiation levels. In Russia they are man-caused radiation levels. Meanwhile any radiation measurement represents total radioactivity. That is why it is hard to assess natural and man-caused contributions to total radioactivity. It is shown that soil radioactivity depends on natural factors including radioactivity of rocks and cosmic radiation as well as man-caused factors including nuclear and non-nuclear technologies. Whole totality of these factors includes unpredictable (non-deterministic) factors - nuclear explosions and radiation accidents, and predictable ones (deterministic) - all the rest. Deterministic factors represent background radioactivity whose trends is the base of the radiation forecast. Non-deterministic factors represent man-caused radiation treatment contribution which is to be controlled. This contribution is equal to the difference in measured radioactivity and radiation background. The way of calculation of background radioactivity is proposed. Contemporary soils are complicated technologically influenced systems with multi-leveled spatial and temporary inhomogeneity of radionuclides distribution. Generally analysis area can be characterized by any set of factors of soil radioactivity including natural and man-caused factors. Natural factors are cosmic radiation and radioactivity of rocks. Man-caused factors are shown on Fig. 1. It is obvious that man-caused radioactivity is due to both artificial and natural emitters. Any result of radiation measurement represents total radioactivity i.e. the sum of activities resulting from natural and man-caused emitters. There is no gauge which could separately measure natural and man-caused radioactivity. That is why it is so hard to assess natural and man-caused contributions to soil radioactivity. It would have been possible if human

  19. Pharmacokinetics of the penicillins in man.

    PubMed

    Barza, M; Weinstein, L

    1976-01-01

    The purpose of this article is to review and summarise those aspects of the pharmacokinetic behaviour of the penicillins that may be of particular interest to the clinician. While these antibiotics differ markedly in their acid stability and oral absorption, misleading inferences may be drawn from simple inspection of the maximal serum concentrations produced by a given dose administered orally. A more accurate picture emerges when serum protein binding and intrinsic activity of the drugs are taken into account. All of the penicillins are readily and actively secreted by the renal tubles and most are eliminated, almost completely unchanged, in the urine. The majority are excreted in small quantities in the bile, but this is a major route for elimination of nafcillin from the body. Distribution of the penicillins in 'non-specialised' sites is excellent. In contrast, penetration of the central nevous system and eye are poor, and of the prostate, minimal. Inflammation reduces the barries to penetration of these areas. However, quantitative data related to this phenomenon in man are few. Probenecid actively competes with the 'export' pump of the meninges and renal tubular cells. This results in an increase in concentrations of the penicillins in the blood and cerebrospinal fluid. The effect of this agent on active secretion of these antibiotics from the eye and biliary tract is minimal. While elimination of the penicillins from the body takes place largely via renal excretion, penicillin V and oxacillin are extensively degraded as well. In contrast to the situation with respect to 'natural' and 'broad-spectrum' penicillins, the serum half-life of the isoxazolyl congeners and nafcillin is only minimally prolonged in the presence of renal failure. These agents are only weakly haemodialyzable, while the other penicillins are rapidly removed from the circulation by this procedure. PMID:797501

  20. Ventilatory drive during face immersion in man.

    PubMed Central

    Mukhtar, M R; Patrick, J M

    1986-01-01

    Four series of experiments have been performed in normal subjects to determine whether face immersion gives rise to a reduction in ventilatory drive. Such a response might be advantageous, like the cardiovascular components of the 'diving response', in prolonging breath-hold diving. In the first series, ventilatory drive was measured indirectly as the maximal voluntary breath-holding time, starting each breath-hold at the same alveolar partial pressures and at the same lung volume. When the face was immersed in cold water, breath-holding times were increased by 14%. The breaking point occurred at a higher alveolar PCO2 and the rate of rise of PCO2 was not affected. Control immersions in warm water had no effect. In the second and third series, subjects lay prone and breathed either air or 5% CO2 through a valve in the bottom of a bowl. Minute ventilation was measured before, during and after 5 min of face immersion in cold water. Transient hypoventilations of 13% and 10% respectively were seen, accompanied by small rises in alveolar PCO2. In control experiments, immersion of the forearm in cold water produced the opposite responses. In the fourth series, a cold wet pack was applied to the face during moderate steady-state exercise. A small irregular hypoventilation was seen, but not in control experiments when a warm pack was applied. Face temperatures fell by about 10 degrees C in these experiments. No material changes were found in the temperatures of the inspired air or of the aural canal. It is concluded that face immersion in cold water causes a modest reduction in ventilatory drive in man. This appears to be a component of the 'diving response'. PMID:3083097

  1. Testosterone and aggressive behavior in man.

    PubMed

    Batrinos, Menelaos L

    2012-01-01

    Atavistic residues of aggressive behavior prevailing in animal life, determined by testosterone, remain attenuated in man and suppressed through familial and social inhibitions. However, it still manifests itself in various intensities and forms from; thoughts, anger, verbal aggressiveness, competition, dominance behavior, to physical violence. Testosterone plays a significant role in the arousal of these behavioral manifestations in the brain centers involved in aggression and on the development of the muscular system that enables their realization. There is evidence that testosterone levels are higher in individuals with aggressive behavior, such as prisoners who have committed violent crimes. Several field studies have also shown that testosterone levels increase during the aggressive phases of sports games. In more sensitive laboratory paradigms, it has been observed that participant's testosterone rises in the winners of; competitions, dominance trials or in confrontations with factitious opponents. Aggressive behavior arises in the brain through interplay between subcortical structures in the amygdala and the hypothalamus in which emotions are born and the prefrontal cognitive centers where emotions are perceived and controlled. The action of testosterone on the brain begins in the embryonic stage. Earlier in development at the DNA level, the number of CAG repeats in the androgen receptor gene seems to play a role in the expression of aggressive behavior. Neuroimaging techniques in adult males have shown that testosterone activates the amygdala enhancing its emotional activity and its resistance to prefrontal restraining control. This effect is opposed by the action of cortisol which facilitates prefrontal area cognitive control on impulsive tendencies aroused in the subcortical structures. The degree of impulsivity is regulated by serotonin inhibiting receptors, and with the intervention of this neurotransmitter the major agents of the neuroendocrine

  2. Testosterone and Aggressive Behavior in Man

    PubMed Central

    Batrinos, Menelaos L.

    2012-01-01

    Atavistic residues of aggressive behavior prevailing in animal life, determined by testosterone, remain attenuated in man and suppressed through familial and social inhibitions. However, it still manifests itself in various intensities and forms from; thoughts, anger, verbal aggressiveness, competition, dominance behavior, to physical violence. Testosterone plays a significant role in the arousal of these behavioral manifestations in the brain centers involved in aggression and on the development of the muscular system that enables their realization. There is evidence that testosterone levels are higher in individuals with aggressive behavior, such as prisoners who have committed violent crimes. Several field studies have also shown that testosterone levels increase during the aggressive phases of sports games. In more sensitive laboratory paradigms, it has been observed that participant’s testosterone rises in the winners of; competitions, dominance trials or in confrontations with factitious opponents. Aggressive behavior arises in the brain through interplay between subcortical structures in the amygdala and the hypothalamus in which emotions are born and the prefrontal cognitive centers where emotions are perceived and controlled. The action of testosterone on the brain begins in the embryonic stage. Earlier in development at the DNA level, the number of CAG repeats in the androgen receptor gene seems to play a role in the expression of aggressive behavior. Neuroimaging techniques in adult males have shown that testosterone activates the amygdala enhancing its emotional activity and its resistance to prefrontal restraining control. This effect is opposed by the action of cortisol which facilitates prefrontal area cognitive control on impulsive tendencies aroused in the subcortical structures. The degree of impulsivity is regulated by serotonin inhibiting receptors, and with the intervention of this neurotransmitter the major agents of the neuroendocrine

  3. Gabriel Richet: the Man and the Scientist.

    PubMed

    Ardaillou, Raymond; Ronco, Pierre

    2016-02-01

    Gabriel Richet who died in Paris in October 2014 was the fourth of a brilliant dynasty of professors of medicine including a Nobel prize, his grandfather, Charles Richet. He behaved courageously during the Second World War and participated in the Campaign of France in 1940 and in the combats in the Vosges Mountains in 1945. His family participated in the resistance during the German occupation of France and three of his parents including his father, one of his brothers and one of his cousins were deported in Germany. At the end of the war, he was with Jean Hamburger the founder of French nephrology at Necker Hospital in Paris. He realized the first hemodialyses in France and was involved in the first allogenic transplantation that was not immediately rejected. From 1961 to 1985, he was the head of a school of nephrology at Tenon Hospital and attracted in his department many young collaborators and scientists. He was the first to describe the role of specialized cells of the collecting duct in the control of acid base equilibrium. He was the subject of a national and international recognition. Founding member of the International Society of Nephrology in 1960, he was elected his President from 1981-1984. His fame could be measured by the number of fellows and visiting facultiesfrom countries all over the world. When he retired in 1985, he left an important legacy involving several departments of nephrology directed by his ancient collaborators. After his retirement, he was an active member of the French Academy of Medicine and devoted much of his time to the history of medicine and, particularly, of nephrology. The main qualities of the man were his constant research of new ideas, his eagerness to work and his open mind to understand others. PMID:26913875

  4. Risk of Severe Acute Exacerbation of Chronic HBV Infection Cancer Patients Who Underwent Chemotherapy and Did Not Receive Anti-Viral Prophylaxis

    PubMed Central

    Shih, Chih-An; Chen, Wen-Chi; Yu, Hsien-Chung; Cheng, Jin-Shiung; Lai, Kwok-Hung; Hsu, Jui-Ting; Chen, Hui-Chun; Hsu, Ping-I

    2015-01-01

    Background Reactivation of HBV replication with an increase in serum HBV DNA and alanine aminotransferase (ALT) activity has been reported in 20–50% of hepatitis B carriers undergoing cytotoxic chemotherapy for cancer treatment. Manifestation of HBV reactivation ranges from asymptomatic self-limiting hepatitis to severe progressive hepatic failure and fatal consequences. Aim To investigate the risk of severe acute exacerbation of chronic HBV infection in HBsAg-positive cancer patients with solid tumors or hematological malignancies who underwent chemotherapy without antiviral prophylaxis. Methods A retrospective review of charts was conducted for HBsAg-positive cancer patients in our institution who underwent chemotherapy and did not receive anti-viral prophylaxis between the periods of July 2007 to January 2013. We investigate the incidence of severe acute exacerbation of chronic HBV infection if these patients with a variety of solid tumors and hematological malignancies. Results A total of 156 patients (hematological malignancies: 16; solid tumors: 140) were included. The incidence of severe acute HBV exacerbation in the patients with hematological malignancy was higher than that in solid tumors (25.0% [4/16] vs 4.3% [6/140]); P = 0.005). Additionally, patients receiving rituximab-based chemotherapy had higher acute exacerbation rate than those with non-rituximab-based chemotherapy (40.0% vs 4.1%, P = 0.001). Among the patients with solid tumors, the incidences of severe acute exacerbation of chronic HBV in hepatocellular carcinoma, colorectal cancer, lung cancer, breast cancer, gynecological cancer, urological tract cancer, head/neck cancer and other solid malignancies were 2.3%, 4.0%, 7.1%, 9.0%, 16.7%, 6.7%, 0% and 0%, respectively. Conclusion Severe acute exacerbation of chronic HBV infection may occur in HBsAg-positive patients with a variety of solid tumors who received chemotherapy without adequate anti-viral prophylaxis. Hematological malignancy and

  5. Complex Disease, Partial Revascularization, and Adverse Outcomes in Patients Treated With Long-Term Warfarin Therapy Who Underwent Percutaneous Coronary Intervention.

    PubMed

    Yazji, Khaled; Kakhi, Sorayya; Ossei-Gerning, Nick; Choudhury, Anirban; Anderson, Richard; Kinnaird, Tim

    2015-08-01

    Patients treated with warfarin who undergo percutaneous coronary intervention (PCI) present a difficult therapeutic problem. Their baseline demographics, procedural characteristics, and 12-month outcomes are poorly defined. We conducted a retrospective analysis of all patients who underwent PCI at a major UK Cardiac Center from 2012 to 2013. Of the 2,675 patients who underwent PCI, 155 were on long-term warfarin treatment (5.8%). Patients on warfarin were older and more likely to have significant co-morbidity than those not on warfarin. The modified Mehran bleed score was higher in patients treated with warfarin versus those not treated (19.0 ± 5.8 vs 15.4 ± 8.0, p = 0.004). Baseline SYNTAX scores were higher in the patients treated with warfarin (18.5 ± 9.1 vs 12.4 ± 3.8, p = 0.0006) as were residual SYNTAX scores (8.3 ± 1.1 vs 3.8 ± 5.9, p = 0.001). Bare metal stents were more frequently used in warfarin-treated patients than those not treated (44.8% vs 26.3%, p <0.0001). Antiplatelet monotherapy was prescribed after PCI in 14.4% of patients treated with warfarin and 0.7% of non-warfarin (p <0.0001), whereas average dual anti-platelet therapy duration was also significantly shorter (4.3 vs 10.7 months, p <0.0001). At 1-year follow-up, target-vessel revascularization (6.5% vs 3.3%, p <0.05), stent thrombosis (5.0% vs 2.6%, p = 0.14), death (10.1% vs 4.6%, p <0.01), and target-vessel revascularization/stent thrombosis/death (21.6% vs 10.5%, p = 0.004) were all more common in the warfarin cohort. In conclusion, patients treated with warfarin who need PCI are a complex cohort, more likely to receive incomplete revascularization, less intense, and shorter durations of antiplatelet therapy, and have adverse 1-year outcomes. More trials of both current DES and newer DES technologies in warfarin-treated patients are needed. PMID:26048850

  6. Man-in-the-control-loop simulation of manipulators

    NASA Technical Reports Server (NTRS)

    Chang, J. L.; Lin, Tsung-Chieh; Yae, K. Harold

    1989-01-01

    A method to achieve man-in-the-control-loop simulation is presented. Emerging real-time dynamics simulation suggests a potential for creating an interactive design workstation with a human operator in the control loop. The recursive formulation for multibody dynamics simulation is studied to determine requirements for man-in-the-control-loop simulation. High speed computer graphics techniques provides realistic visual cues for the simulator. Backhoe and robot arm simulations are implemented to demonstrate the capability of man-in-the-control-loop simulation.

  7. Intergration effects of D-shaped, underwing, aft-mounted, separate-flow, flow-through nacelles on a high-wing transport

    NASA Technical Reports Server (NTRS)

    Lamb, Milton; Carlson, John R.; Pendergraft, Odis C., Jr.

    1987-01-01

    An experimental investigation was conducted in the Langley 16-Foot Transonic Tunnel at freestream Mach numbers from 0.70 to 0.82 and angles of attack from -3.0 to 4.0 deg to determine the integration effects of D-shaped, underwing, aft-mounted, separate-flow, flow-through nacelles on a high-wing transonic transport configuration. The results showed that the aft-mounted nacelle/pylon produced an increase in lift over that of the wing-body configuration by pressurizing much of the wing lower surface in front of the pylon. For the D-shaped nacelle, a substantial region of supersonic flow over the wing, aft of the lip of the nacelle, cancelled the reduction in drag caused by the increase in pressures ahead of the lip, to increase interference and form drag compared with a similar circular-shaped nacelle. The installed drag of the D=shaped nacelle was essentially the same as that of an aft-mounted circular nacelle from a previous investigation.

  8. The Mouse-colored Tyrannulet (Phaeomyias murina) is a species complex that includes the Cocos Flycatcher (Nesotriccus ridgwayi), an island form that underwent a population bottleneck.

    PubMed

    Zucker, Marc R; Harvey, Michael G; Oswald, Jessica A; Cuervo, Andrés; Derryberry, Elizabeth; Brumfield, Robb T

    2016-08-01

    Simultaneous examination of evolutionary history in island forms and closely related mainland relatives can provide reciprocal insight into the evolution of island and mainland faunas. The Cocos Flycatcher (Nesotriccus ridgwayi) is a small tyrant flycatcher (Tyrannidae) endemic to Cocos Island, an oceanic island in the eastern Pacific Ocean. We first established its close relationship to the mainland species Mouse-colored Tyrannulet (Phaeomyias murina) using a phylogeny from genome-wide ultraconserved elements and exons. We then used mitochondrial DNA to explore the relationships between Nesotriccus and Phaeomyias populations from across its distribution in Central and South America. We found that Nesotriccus is nested within the Phaeomyias evolutionary tree, and that Phaeomyias represents a complex of at least four evolutionarily distinct species that differ in plumage, voice, and habitat association. Nesotriccus underwent a population bottleneck subsequent to its divergence from Central American and northern South American Phaeomyias populations in the middle Pleistocene. The 46 UCE loci containing alleles that are fixed between the two species are widely distributed across the genome, which suggests that selective or neutral processes responsible for divergence have occurred genome-wide. Overall, our simultaneous examination of Phaeomyias and Nesotriccus revealed divergent levels of genetic diversity and evolutionary histories between island and mainland forms. PMID:27126184

  9. The biological activity of propolis-containing toothpaste on oral health environment in patients who underwent implant-supported prosthodontic rehabilitation.

    PubMed

    Morawiec, Tadeusz; Dziedzic, Arkadiusz; Niedzielska, Iwona; Mertas, Anna; Tanasiewicz, Marta; Skaba, Dariusz; Kasperski, Jacek; Machorowska-Pieniążek, Agnieszka; Kucharzewski, Marek; Szaniawska, Karolina; Więckiewicz, Włodzimierz; Więckiewicz, Mieszko

    2013-01-01

    The soft and periodontal tissues surrounding dental implants are particularly susceptible to bacteria invasion and inflammatory reactions due to complex histological structures. This study was carried out to investigate the influence of a propolis-containing hygienic agent on selected oral health parameters, oral microflora, and the condition of periodontal health. Sixteen subjects who underwent an oral rehabilitation with dental implants were selected and randomly assigned into two groups, which received a newly formulated propolis-containing toothpaste (3% (CA)) or a negative control without an active ingredient (CC). Approximal plaque index (API), oral hygiene index (OHI, debris component), and sulcus bleeding index (SBI) were assessed in three subsequent stages. During the first and last examinations, the swabs were employed for microbiological inoculation. Propolis-containing toothpaste was found to be distinctively effective in improving oral health and the occurrence of gingivitis triggered by dental plaque. The qualitative and quantitative changes in oral bacteria spectrum were observed. Antibacterial measures containing propolis might be used as a natural adjuvant to other active substances in individuals with a high risk of periodontal problems against pathogenic oral microflora. PMID:23762153

  10. Analysis of incidence of keratoconus in relatives of patients who underwent corneal transplant due to advanced keratoconus using the Orbscan II topographic graphs

    NASA Astrophysics Data System (ADS)

    López Olazagasti, Estela; Hernández y del Callejo, César E.; Ibarra-Galitzia, Jorge; Ramírez-Zavaleta, Gustavo; Tepichín, Eduardo

    2011-10-01

    Keratoconus is a corneal disease in which the cornea assumes a conical shape due to an irregular alteration of the internal structure of the corneal tissue and sometimes is progressive, especially in young people. Anatomically, the main signs of keratoconus are thinning of the cornea in its central or paracentral region, usually accompanied by an increase in this part of a high irregular astigmatism, with a consequent loss of vision. Its diagnosis requires a thorough study including the family history, a complete ophthalmologic examination and imaging studies. This diagnosis allows classifying the type of keratoconus, which allow determining options of management, with what it is possible to establish a visual prognosis of each eye. One of the indicators that help in the diagnosis of keratoconus is an inherited familiar propensity. The literature reports an incidence of keratoconus of 11%1 in first-degree relatives of patients with keratoconus. Results suggest an ethnic dependence, which implies that the knowledge of the tendency of keratoconus in the Mexican population is important. In this work, we present the preliminary results of the study realized to a group of relatives of patients who underwent corneal transplant by advanced keratoconus using Orbscan II topographic diagnosis, to determine the predisposition to Keratoconus in this group.e

  11. Comparison of MMF with prednisone in terms of rejection and duration of activity of transplant in rabbits that underwent retroperitoneal heterotopic heart transplantation

    PubMed Central

    Aygün, Fatih; Efe, Duran; Durgut, Kadir

    2015-01-01

    Summary Aim In this study, mycophenolate mofetil (MMF) and methylprednisolone (MP) were compared in terms of rejection and duration of activity of the transplant in New Zealand rabbits that underwent retroperitoneal heart transplantation. Methods Retroperitoneal heart transplantation was performed in New Zealand white rabbits. The animals were divided into two groups. MMF group (group 1) (10 donors, 10 recipients): 12.5 mg/kg MMF was administered orally for two days prior to the surgery; MP group (group 2) (nine donors, nine recipients): 2 mg/kg MP was administered intramuscularly for two days prior to the surgery. After the operation, we waited until all motor activity in the transplanted heart had stopped. The transplant was then removed and the recipient was sacrificed. A donor in the MP group was excluded since it died before the motor activity had stopped. Results No statistically significant difference was found between the groups in terms of rejection score (p = 0.865). However, duration of motor activity was found to be statistically significantly longer in the MMF group, compared to the MP group (p = 0.013). Conclusion In this experimental study, MMF was similar to MP in terms of rejection but had better efficacy in terms of duration of motor activity of the transplant. PMID:26592904

  12. The Biological Activity of Propolis-Containing Toothpaste on Oral Health Environment in Patients Who Underwent Implant-Supported Prosthodontic Rehabilitation

    PubMed Central

    Morawiec, Tadeusz; Dziedzic, Arkadiusz; Niedzielska, Iwona; Mertas, Anna; Tanasiewicz, Marta; Skaba, Dariusz; Kasperski, Jacek; Machorowska-Pieniążek, Agnieszka; Kucharzewski, Marek; Szaniawska, Karolina; Więckiewicz, Włodzimierz; Więckiewicz, Mieszko

    2013-01-01

    The soft and periodontal tissues surrounding dental implants are particularly susceptible to bacteria invasion and inflammatory reactions due to complex histological structures. This study was carried out to investigate the influence of a propolis-containing hygienic agent on selected oral health parameters, oral microflora, and the condition of periodontal health. Sixteen subjects who underwent an oral rehabilitation with dental implants were selected and randomly assigned into two groups, which received a newly formulated propolis-containing toothpaste (3% (CA)) or a negative control without an active ingredient (CC). Approximal plaque index (API), oral hygiene index (OHI, debris component), and sulcus bleeding index (SBI) were assessed in three subsequent stages. During the first and last examinations, the swabs were employed for microbiological inoculation. Propolis-containing toothpaste was found to be distinctively effective in improving oral health and the occurrence of gingivitis triggered by dental plaque. The qualitative and quantitative changes in oral bacteria spectrum were observed. Antibacterial measures containing propolis might be used as a natural adjuvant to other active substances in individuals with a high risk of periodontal problems against pathogenic oral microflora. PMID:23762153

  13. Physiologically constrained aerocapture for manned Mars missions

    NASA Technical Reports Server (NTRS)

    Lyne, James Evans

    1992-01-01

    Aerobraking has been proposed as a critical technology for manned missions to Mars. The variety of mission architectures currently under consideration presents aerobrake designers with an enormous range of potential entry scenarios. Two of the most important considerations in the design of an aerobrake are the required control authority (lift-to-drag ratio) and the aerothermal environment which the vehicle will encounter. Therefore, this study examined the entry corridor width and stagnation-point heating rate and load for the entire range of probable entry velocities, lift-to-drag ratios, and ballistic coefficients for capture at both Earth and Mars. To accomplish this, a peak deceleration limit for the aerocapture maneuvers had to be established. Previous studies had used a variety of load limits without adequate proof of their validity. Existing physiological and space flight data were examined, and it was concluded that a deceleration limit of 5 G was appropriate. When this load limit was applied, numerical studies showed that an aerobrake with an L/D of 0.3 could provide an entry corridor width of at least 1 degree for all Mars aerocaptures considered with entry velocities up to 9 km/s. If 10 km/s entries are required, an L/D of 0.4 to 0.5 would be necessary to maintain a corridor width of at least 1 degree. For Earth return aerocapture, a vehicle with an L/D of 0.4 to 0.5 was found to provide a corridor width of 0.7 degree or more for all entry velocities up to 14.5 km/s. Aerodynamic convective heating calculations were performed assuming a fully catalytic, 'cold' wall; radiative heating was calculated assuming that the shock layer was in thermochemical equilibrium. Heating rates were low enough for selected entries at Mars that a radiatively cooled thermal protection system might be feasible, although an ablative material would be required for most scenarios. Earth return heating rates were generally more severe than those encountered by the Apollo vehicles

  14. Ion Inculetz- Political man and scientist

    NASA Astrophysics Data System (ADS)

    Gaina, A.; Ionescu-Pallas, N. I.

    1993-06-01

    It is well known, that the president of the first Moldavian Parliament in 1918 was Ion Inculetz (borne on 5 april, 1884, Rezeni vill., Lapusna county, Basarabia - died on 19 november 1940, Bucharest, regraved in Barnova, near Iasi). On 24 January 1918 this Parliament claimed the independence of Basarabia from the Russia (The Democratic Republic of Moldova). On 27 march of the same year in a solennele session the Parliament claimed "The Democratic Republic of Moldova (Basarabia) in its borders between Prut, Dniester rivers, Black Sea, and old borders with Austria, rupted by Russia more than one hundred years from the body of old Moldova, due to the historical right and due to the right of the selfdetermination of peoples, is unifying forever with She's mother Romania ". After the Unification Ion Inculetz activated as representative of Basarabia in the Romanian Parliament. He was a man of democratic views, a partisan of social-democracy in Russia, as well as in Romania after the unification. The progress of peoples was one of His main political goals. It is less known, however, that Inculetz was a remarkable physicist. This is the subject of the conference. After the finish of the secondary studies in Chisinau, He entered to Jur'ev (actually Tartu- Estonia) University Medecine Department, but after one year of studies He moved to Sankt-Petersburg Imperial University, where He specialized in physics and mathematics. After the finish of the Physical Mathematical Department he became private-docent (Associate Professor). Concomittantly He taught methematics at one of the comercial schhols in Sankt Petersburg. In the same time he was a Scientific Secretary of the journal "Nauchnoie Obozrenie" ("Scientific Review") and a researcher at the Meteorological Observatory in Sankt-Petersburg (since 1914). Since 1912 till 1917 He published a series of papers in the fields of physics and meteorology, particularly concerned to anodic rays, Krooks tubes, radiactivity, Doppler effect

  15. Diffuse large B cell lymphoma of the cranial vault: two case reports.

    PubMed

    Tashiro, Ryosuke; Kanamori, Masayuki; Suzuki, Hiroyoshi; Utsunomiya, Akihiro; Meguro, Kuniaki; Uenohara, Hiroshi; Tominaga, Teiji

    2015-10-01

    Malignant lymphoma of the cranial vault is a rare entity and the tumor growth patterns are not well understood. Here we report two cases of malignant lymphoma involving the scalp and epidural space with slight changes in the intervening skull. A 63-year-old woman presented with a scalp mass in her right frontal area. Computed tomography (CT) and magnetic resonance (MR) imaging demonstrated mass lesions in the scalp and epidural space with slight osteolytic changes in the intervening skull. She underwent resection of the lesions. A 53-year-old man presented with a mass in his right frontal area. CT and MR imaging showed mass lesions in the scalp and epidural space without changes in the skull. He underwent resection of the lesions. The histopathological diagnosis was diffuse large B cell lymphoma in both cases. Microscopic examination of the intervening skull found that the bone marrow was diffusely replaced by lymphoma cells, and lymphoma cells extended to the extra- or intra-cranial space along the emissary veins without destruction of the cortical or trabecular bone. These histopathological findings explain the radiological findings and provide the clues to elucidate the mechanism of extension of cranial vault lymphoma. PMID:26177806

  16. 10. Historic American Buildings Survey W. N. Manning, Photographer, September ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey W. N. Manning, Photographer, September 10, 1935 MANTEL AND WINDOW TREATMENT IN PARLOR, WEST FRONT ROOM - James Ellington House, Oak Bowery Road vicinity, Gold Hill, Lee County, AL

  17. 4. Historic American Buildings Survey W. N. Manning, Photographer, Sept. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, Sept. 10, 1935 VIEW OF FRONT PORCH SHOWING DOOR AND WINDOW DETAIL - James Ellington House, Oak Bowery Road vicinity, Gold Hill, Lee County, AL

  18. 5. Historic American Buildings Survey W. N. Manning, Photographer, September ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey W. N. Manning, Photographer, September 10, 1935 CLOSE-UP OF COLUMN BASE ON FRONT PORCH - James Ellington House, Oak Bowery Road vicinity, Gold Hill, Lee County, AL

  19. 7. Historic American Buildings Survey W. N. Manning, Photographer, September ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey W. N. Manning, Photographer, September 10, 1935 VIEW IN HALL SHOWING FRONT DOOR AND TWO SIDE DOORS - James Ellington House, Oak Bowery Road vicinity, Gold Hill, Lee County, AL

  20. 3. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, March 14, 1935 VIEW IN DINING ROOM SHOWING JAPANESE CHINA CLOSET, S.W. - John Bullard House, Harrogate Springs Road vicinity, Wetumpka, Elmore County, AL

  1. 8. Historic American Buildings Survey W. N. Manning, Photographer, May ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey W. N. Manning, Photographer, May 16, 1935 MANTEL AND CHINA CLOSET IN DINING ROOM, N. ROOM - McDonald-Smartt House, 315 North Randolph Street, Eufaula, Barbour County, AL

  2. 10. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey W. N. Manning, Photographer, January 4, 1935. DINING ROOM INTERIOR. SHOWING CHINA CLOSETS - Dr. E. W. Daugette House, 601 North Pelham Road, Jacksonville, Calhoun County, AL

  3. 4. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, March 29, 1935 MANTEL AND BUILT-IN CHINA CLOSET IN DINING ROOM, IN BASEMENT - Powell House, State Highway 97 (County Road 29), Lowndesboro, Lowndes County, AL

  4. 6. Historic American Buildings Survey W. N. Manning, Photographer, February ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey W. N. Manning, Photographer, February 25, 1935 BUILT IN CHINA CABINET IN DINING ROOM, S.W. ROOM - Hunter-Callaway House, 811 North Maple Street, Tuskegee, Macon County, AL

  5. 5. Historic American Buildings Survey W. N. Manning, Photographer, February ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey W. N. Manning, Photographer, February 25, 1935 DOUBLE DOOR IN DINING ROOM OPENING INTO PARLOR - Hunter-Callaway House, 811 North Maple Street, Tuskegee, Macon County, AL

  6. 8. Historic American Buildings Survey W. N. Manning, Photographer, June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey W. N. Manning, Photographer, June 13, 1935. MANTEL AND DOOR IN N.E. BED ROOM, UPSTAIRS - Beeland-Stanley House, 218 East Commerce Street, Greenville, Butler County, AL

  7. 1. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. GENERAL FRONT VIEW. - NORTH ELEVATION - First White House of the Confederacy, 625 Washington Street (moved from Bibb & Lee Streets), Montgomery, Montgomery County, AL

  8. 2. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. WEST SIDE ELEVATION + REAR VIEW. - First White House of the Confederacy, 625 Washington Street (moved from Bibb & Lee Streets), Montgomery, Montgomery County, AL

  9. 5. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. DETAIL OF FIREPLACE. - First White House of the Confederacy, 625 Washington Street (moved from Bibb & Lee Streets), Montgomery, Montgomery County, AL

  10. 3. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. STAIRWAY. - First White House of the Confederacy, 625 Washington Street (moved from Bibb & Lee Streets), Montgomery, Montgomery County, AL

  11. 4. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. VIEW FROM DRAWING ROOM INTO DINING ROOM. - First White House of the Confederacy, 625 Washington Street (moved from Bibb & Lee Streets), Montgomery, Montgomery County, AL

  12. 6. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey W. N. Manning, Photographer, April 16, 1934. INTERIOR (BEDROOM) - First White House of the Confederacy, 625 Washington Street (moved from Bibb & Lee Streets), Montgomery, Montgomery County, AL

  13. 10. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey W. N. Manning, Photographer, January 24, 1935 SHOWING WALL AND HALL DOOR UPSTAIRS, OPENING INTO BED ROOM - Doctor Glover House, Weaver Road, Weaver, Calhoun County, AL

  14. 5. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey W. N. Manning, Photographer, March 17, 1934. FIREPLACE AND MANTLE (LIVING ROOM) - Doctor Harper House, State Highway 219 & County Road 344, Selma, Dallas County, AL

  15. 1. Historic American Buildings Survey W. N. Manning, Photographer, July ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, July 19, 1935. FRONT AND SIDE VIEW (WEST FRONT) - Seale-Mosley House, County Road 40 (moved from original location), Peachburg, Bullock County, AL

  16. Monkeys as a source of viral diseases in man

    NASA Technical Reports Server (NTRS)

    Pille, E. R.

    1986-01-01

    Under institutional scientific-research conditions, during contact with monkeys or their tissues, there is a danger of infection of the associates by simian viruses which are pathogenic to man. Presented in this paper is information on these stimulants.

  17. 14. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 MANTEL AND DOOR IN DINING ROOM, N.E. - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  18. 17. Historic American Buildings Survey W. N. Manning, March 21, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Historic American Buildings Survey W. N. Manning, March 21, 1935, Photographer MANTEL IN S.W. ROOM UPSTAIRS - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  19. 4. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 CLOSE- UP OF COLUMN CAPITAL TOWARD S.E. FROM BALCONY - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  20. 3. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 CLOSE- UP OF FRONT DOORS, BALCONY AND 2 COLUMNS - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  1. 16. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 STAIR WELL LOOKING TO THIRD FLOOR ATTIC - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  2. 15. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 STAIRS IN REAR OF HALL, WINDOW IN REAR N. - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  3. 8. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 DOOR TREATMENT FROM HALL INTO PARLOR - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  4. 6. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 HALL AND STAIRWAY TOWARD REAR OF HALL, ALSO CEILING TREATMENT - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  5. 9. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 MANTEL AND WINDOW TREATMENT, ALSO CEILING IN PARLOR - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  6. 19. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 MANTEL IN N.E. ROOM UPSTAIRS - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  7. 1. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 FRONT AND SIDE VIEW S.W. - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  8. 5. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 N. TOWARDS FRONT ENTRANCE SHOWING 2 HALL DOORS AND STAIR DETAIL - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  9. 13. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 MANTEL IN S.E. FRONT ROOM ALSO WINDOW AND CEILING TREATMENT - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  10. 11. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 CEILING TREATMENT - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  11. 7. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 PARLOR DOOR TREATMENT IN HALL - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  12. 18. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 MANTEL IN S.E. ROOM UPSTAIRS - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  13. 2. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 REAR AND SIDE VIEW N.E. - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  14. 6. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey W. N. Manning, Photographer, March 7, 1935 STAIRWAY AND DOUBLE DOOR IN REAR OF HALL FACING SOUTH - G. Y. Lamar House, U.S. Highway 29 (State Highway 15), Tuskegee, Macon County, AL

  15. 3. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, March 7, 1935 BALCONY AND DOOR TREATMENT FACING NORTH - G. Y. Lamar House, U.S. Highway 29 (State Highway 15), Tuskegee, Macon County, AL

  16. 10. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey W. N. Manning, Photographer, March 27, 1935 CLOSE-UP OF MARBLE MANTEL IN PARLOR - Montgomery-Jones-Whitaker House, County Road 4 (Reynolds Mill Road), Prattville, Autauga County, AL

  17. 15. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Historic American Buildings Survey W. N. Manning, Photographer, March 28, 1935 MARBLE MANTEL IN LIVING ROOM (S.W. ROOM) - Haygood House, State Highway 97 (County Road 29), Lowndesboro, Lowndes County, AL

  18. 23. Historic American Buildings Survey W. N. Manning, Photographer, October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Historic American Buildings Survey W. N. Manning, Photographer, October 25, 1935 MARBLE MANTEL IN WEST BED ROOM - Colonel Charles Teed Pollard House (Mansion), 117 Jefferson Street, Montgomery, Montgomery County, AL

  19. 7. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey W. N. Manning, Photographer, April 25, 1934. DETAIL OF FIREPLACE IN DIRECTOR'S ROOM. - First National Bank, Jefferson Street & Fountain Road, Huntsville, Madison County, AL

  20. 4. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, March 18, 1935 DOOR TREATMENT, FROM HALL TO WEST FRONT ROOM - Black-Gilling House, County Road 44, Dudleyville, Tallapoosa County, AL

  1. 15. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Historic American Buildings Survey W. N. Manning, Photographer, January 26, 1935 FRONT AND SIDE VIEW OF OLD STORE, S.E. - Freeman-Caver-Christian House, Upper Friendship Road, Oxford, Calhoun County, AL

  2. 4. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, January 26, 1935 MANTEL IN SOUTH LIVING ROOM (old fashion parlor) - Freeman-Caver-Christian House, Upper Friendship Road, Oxford, Calhoun County, AL

  3. 14. Historic American Buildings Survey W. N. Manning, Photographer, January ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Historic American Buildings Survey W. N. Manning, Photographer, January 26, 1935 S.E. CORNER OF OLD SLAVE KITCHEN N. OF HOUSE - Freeman-Caver-Christian House, Upper Friendship Road, Oxford, Calhoun County, AL

  4. Biology as a Study of Man and Society

    ERIC Educational Resources Information Center

    Hurd, Paul DeHart

    1971-01-01

    Biology ought to be taught within the context of human culture; "man" can be the "type animal." Consideration should be given to questions of race, population, food resources, environmental quality, intelligence, genetic engineering, and organ transplants. (AL)

  5. 4. Historic American Buildings Survey W. N. Manning, Photographer, Feb. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey W. N. Manning, Photographer, Feb. 2, 1934. ORIG.? - COTTAGE TO SIDE OF HELEN KELLER HOUSE. (OLD OFFICE?) - Helen Keller House, 300 West North Commons, Tuscumbia, Colbert County, AL

  6. 6. View of double man door on north elevation of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View of double man door on north elevation of power plant, looking south - Naval Air Station Fallon, Power Plant, 800 Complex, off Carson Road near intersection of Pasture & Berney Roads, Fallon, Churchill County, NV

  7. 5. View bay door and single man door on north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. View bay door and single man door on north elevation of power plant, looking south - Naval Air Station Fallon, Power Plant, 800 Complex, off Carson Road near intersection of Pasture & Berney Roads, Fallon, Churchill County, NV

  8. 3. Historic American Buildings Survey W. N. Manning, Photographer, June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, June 12, 1935. PART OF FRONT AND OLD LAW OFFICE, NOW USED AS KITCHEN - Will Crenshaw Plantation (House), County Road 54, Greenville, Butler County, AL

  9. 2. Historic American Buildings Survey W. N. Manning, Photographer, June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, June 11, 1935. OLD LAW OFFICE (REPRODUCTION) (FROM EMERGENCY RELIEF ADMINISTRATION PHOTO) - Nolan Crenshaw House, County Road 54, Greenville, Butler County, AL

  10. 2. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey W. N. Manning, Photographer, April 24, 1934. FRONT (GENERAL VIEW). (MAIN ELEV.) - State Bank of Alabama, Decatur Branch, Bank Street & Wilson Avenue, Decatur, Morgan County, AL

  11. 1. Historic American Buildings Survey W. N. Manning, Photographer, Feb. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, Feb. 10th, 1934. MAIN ELEVATION - (FRONT, GEN'L. VIEW) - State Bank of Alabama, Decatur Branch, Bank Street & Wilson Avenue, Decatur, Morgan County, AL

  12. 3. Historic American Buildings Survey W. N. Manning, Photographer, April ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, April 25, 1934. VIEW ACROSS PARK TOWARD CLIFF AND BANK BUILDING. - First National Bank, Jefferson Street & Fountain Road, Huntsville, Madison County, AL

  13. 3. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 CLOSE- UP OF FRONT PORCH, SOUTH - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  14. 11. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 MANTEL IN LIVING ROOM, UPSTAIRS - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  15. 14. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 MANTEL IN S.W. BED ROOM UPSTAIRS - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  16. 13. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 MANTEL IN N.W. BED ROOM, UPSTAIRS - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  17. 9. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 CHINA CABINET IN DINING ROOM, S.W. ROOM - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  18. 12. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 MANTEL IN N.E. BED ROOM, UPSTAIRS - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  19. 1. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 FRONT AND SIDE VIEW, S.W. - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL

  20. 6. Historic American Buildings Survey W. N. Manning, Photographer, March ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey W. N. Manning, Photographer, March 26, 1935 STAIRWAY AND REAR HALL DOORS - Pope-Golson House, 815 Shadow Lane (moved from original location), Prattville, Autauga County, AL