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Sample records for 6th annual genomics

  1. 6th Annual European Antibody Congress 2010

    PubMed Central

    2011-01-01

    The 6th European Antibody Congress (EAC), organized by Terrapinn Ltd., was held in Geneva, Switzerland, which was also the location of the 4th and 5th EAC.1,2 As was the case in 2008 and 2009, the EAC was again the largest antibody congress held in Europe, drawing nearly 250 delegates in 2010. Numerous pharmaceutical and biopharmaceutical companies active in the field of therapeutic antibody development were represented, as were start-up and academic organizations and representatives from the US Food and Drug Administration (FDA). The global trends in antibody research and development were discussed, including success stories of recent marketing authorizations of golimumab (Simponi®) and canakinumab (Ilaris®) by Johnson & Johnson and Novartis, respectively, updates on antibodies in late clinical development (obinutuzumab/GA101, farletuzumab/MORAb-003 and itolizumab/T1 h, by Glycart/Roche, Morphotek and Biocon, respectively) and success rates for this fast-expanding class of therapeutics (Tufts Center for the Study of Drug Development). Case studies covering clinical progress of girentuximab (Wilex), evaluation of panobacumab (Kenta Biotech), characterization of therapeutic antibody candidates by protein microarrays (Protagen), antibody-drug conjugates (sanofi-aventis, ImmunoGen, Seattle Genetics, Wyeth/Pfizer), radio-immunoconjugates (Bayer Schering Pharma, Université de Nantes) and new scaffolds (Ablynx, AdAlta, Domantis/GlaxoSmithKline, Fresenius, Molecular Partners, Pieris, Scil Proteins, Pfizer, University of Zurich) were presented. Major antibody structural improvements were showcased, including the latest selection engineering of the best isotypes (Abbott, Pfizer, Pierre Fabre), hinge domain (Pierre Fabre), dual antibodies (Abbott), IgG-like bispecific antibodies (Biogen Idec), antibody epitope mapping case studies (Eli Lilly), insights in FcγRII receptor (University of Cambridge), as well as novel tools for antibody fragmentation (Genovis). Improvements

  2. Summary of the 6th Annual Bladder Cancer Think Tank: new directions in urologic research.

    PubMed

    Svatek, Robert S; Rosenberg, Jonathan E; Galsky, Matthew D; Lee, Cheryl T; Latini, David M; Bochner, Bernard H; Weizer, Alon Z; Apolo, Andrea B; Sridhar, Srikala S; Kamat, Ashish M; Hansel, Donna; Flaig, Thomas W; Smith, Norm D; Lotan, Yair

    2013-10-01

    The 6th Annual Bladder Cancer Think Tank brought together a multidisciplinary group of clinicians, researchers, and representatives from the National Cancer Institute and Industry in an effort to advance bladder cancer research efforts. This year's meeting comprised panel discussions and research involving 5 separate working groups, including the Survivorship, Clinical Trials, Standardization of Care, Data Mining, and Translational Science working groups. In this manuscript, the accomplishments and objectives of the working groups are summarized. Notable efforts include: (1) the development of a survivorship care plan for early and late-stage bladder cancer; (2) the development of consensus criteria for eligibility and endpoints for bladder cancer clinical trials; (3) an improved understanding of current practice patterns regarding the use of perioperative chemotherapy in an effort to standardize care; (4) creation of a comprehensive handbook to assist researchers with developing bladder cancer databases; and (5) identification of response to therapy of high-grade non muscle invasive disease through a collaborative exchange of expertise and resources.

  3. Proceedings from the 6th Annual University of Calgary Leaders in Medicine Research Symposium.

    PubMed

    Roberts, Jodie I; Beatty, Jennifer K; Peplowski, Michael A; Keough, Michael B; Yipp, Bryan G; Hollenberg, Morley D; Beck, Paul L

    2015-12-04

    On November 14, 2014, the Leaders in Medicine (LIM) program at the Cumming School of Medicine, University of Calgary hosted its 6th Annual Research Symposium. Dr. Danuta Skowronski, Epidemiology Lead for Influenza and Emerging Respiratory Pathogens at the British Columbia Centre for Disease Control (BCCDC), was the keynote speaker and presented a lecture entitled "Rapid response research during emerging public health crises: influenza and reflections from the five year anniversary of the 2009 pandemic". The LIM symposium provides a forum for both LIM and non-LIM medical students to present their research work, either as an oral or poster presentation. There were a total of six oral presentations and 77 posters presented. 
The oral presentations included: Swathi Damaraju, "The role of cell communication and 3D Cell-Matrix environment in a stem cell-based tissue engineering strategy for bone repair"; Menglin Yang, "The proteolytic activity of Nepenthes pitcher fluid as a therapeutic for the treatment of celiac disease"; Amelia Kellar, "Monitoring pediatric inflammatory bowel disease - a retrospective analysis of transabdominal ultrasound"; Monica M. Faria-Crowder, "The design and application of a molecular profiling strategy to identify polymicrobial acute sepsis infections"; Waleed Rahmani, "Hair follicle dermal stem cells regenerate the dermal sheath, repopulate the dermal papilla and modulate hair type"; and, Laura Palmer, "A novel role for amyloid beta protein during hypoxia/ischemia". 
The article on the University of Calgary Leaders in Medicine Program, "A Prescription that Addresses the Decline of Basic Science Education in Medical School," in a previous issue of CIM (2014 37(5):E292) provides more details on the program. Briefly, the LIM Research Symposium has the following objectives: (1) to showcase the impressive variety of projects undertaken by students in the LIM Program as well as University of Calgary medical students; (2) to encourage medical

  4. 6th Annual European Antibody Congress 2010: November 29-December 1, 2010, Geneva, Switzerland.

    PubMed

    Beck, Alain; Wurch, Thierry; Reichert, Janice M

    2011-01-01

    The 6th European Antibody Congress (EAC), organized by Terrapinn Ltd., was held in Geneva, Switzerland, which was also the location of the 4th and 5th EAC. As was the case in 2008 and 2009, the EAC was again the largest antibody congress held in Europe, drawing nearly 250 delegates in 2010. Numerous pharmaceutical and biopharmaceutical companies active in the field of therapeutic antibody development were represented, as were start-up and academic organizations and representatives from the US Food and Drug Administration FDA. The global trends in antibody research and development were discussed, including success stories of recent marketing authorizations of golimumab (Simponi®) and canakinumab (Ilaris®) by Johnson & Johnson and Novartis, respectively, updates on antibodies in late clinical development (obinutuzumab/GA101, farletuzumab/MORAb-003 and itolizumab/T1 h, by Glycart/Roche, Morphotek and Biocon, respectively) and success rates for this fast-expanding class of therapeutics (Tufts Center for the Study of Drug Development). Case studies covering clinical progress of girentuximab (Wilex), evaluation of panobacumab (Kenta Biotech), characterization of therapeutic antibody candidates by protein microarrays (Protagen), antibody-drug conjugates (sanofi-aventis, ImmunoGen, Seattle Genetics, Wyeth/Pfizer), radio-immunoconjugates (Bayer Schering Pharma, Université de Nantes) and new scaffolds (Ablynx, AdAlta, Domantis/GlaxoSmithKline, Fresenius, Molecular Partners, Pieris, Scil Proteins, Pfizer, University of Zurich) were presented. Major antibody structural improvements were showcased, including the latest selection engineering of the best isotypes (Abbott, Pfizer, Pierre Fabre), hinge domain (Pierre Fabre), dual antibodies (Abbott), IgG-like bispecific antibodies (Biogen Idec), antibody epitope mapping case studies (Eli Lilly), insights in FcγRII receptor (University of Cambridge), as well as novel tools for antibody fragmentation (Genovis). Improvements of

  5. 6th Annual Midwest Conference for Undergraduate Women in Physics, January 18-20, 2013, Urbana, Illinois

    SciTech Connect

    Pitts, Kevin T.

    2016-04-28

    This document is the program for the 6th Annual Midwest Conference for Undergraduate Women in Physics, which was held at the University of Illinois at Urbana-Champaign on January 18-20, 2013. The goals of the conference were to foster a culture in which undergraduate women are encouraged and supported to pursue, and also to succeed in, higher education in physics; to provide career information to students in physics and related fields; to give women the resources, motivation, and confidence to apply to graduate school and successfully complete a Ph.D. program in Physics; to provide information and dispel misconceptions about the application process for graduate school and the diverse employment opportunities in physics and related fields, enabling women to make more informed decisions about their goals and attain them; and to connect female physics students with successful female physicists to whom they can relate and who can act as inspirational role models and mentors.

  6. Highlights from the 6th Annual University of Calgary Leaders in Medicine Research Symposium and the Keynote Address by Dr. Danuta Skowronski.

    PubMed

    Roberts, Jodie I; Beatty, Jennifer K; Peplowski, Michael A; Keough, Michael B; Yipp, Bryan G; Hollenberg, Morley D; Beck, Paul L

    2015-12-04

    The Leaders in Medicine (LIM) Program at the University of Calgary hosted its 6th Annual Research Symposium on November 14, 2014, showcasing the quality and breadth of work performed by students at the Cumming School of Medicine. Participation at this year's event was our most successful to date, with a total of six oral and 77 poster presentations during the afternoon symposium. For a detailed description of the work presented at the symposium, please see the Proceedings from the 6th Annual University of Calgary Leaders in Medicine Research Symposium published in this issue of Clinical and Investigative Medicine.

  7. Meeting Report: "Proteomics from Discovery to Function:" 6th Annual Meeting of Proteomics Society, India and International Conference-A Milestone for the Indian Proteomics Community.

    PubMed

    Gupta, Shabarni; Reddy, Panga Jaipal; Ray, Sandipan; Atak, Apurva; Gollapalli, Kishore; Jain, Rekha; Shah, Veenita Grover; Ghantasala, Saicharan; Kumar, Saurabh; Pandala, Narendra Goud; Phapale, Prasad; Pandey, Vishnu Kumar; Zingde, Surekha; Srivastava, Sanjeeva

    2015-06-01

    Proteomics is at the epicenter of post-genomics biotechnologies that are currently driving the next generation system science. Moreover, proteomics is a truly global science. The 6(th) Annual Meeting of Proteomics Society, India (PSI) and International Conference on "Proteomics from Discovery to Function" held from December 7-9, 2014, was a transformative endeavor for global proteomics, bringing together the luminaries in the field of proteomics for the very first time in India. This meeting report presents the lessons learned and the highlights of this international scientific conference that was comprised of nine thematic sessions, pre- and post-conference workshops, and an opportunity to cultivate enduring collaborations for proteomics science to benefit both India and global society. The conference had an unforgettable impression on the participants: for the first time, India hosted past and present President and Council members from the Human Proteome Organization (HUPO), along with eminent scientists and young scholars from India and abroad in the field of proteomics at such a large scale, a major highlight of this international event. In all, the PSI 2014 was a milestone conference that has firmly poised the Indian life sciences community as a leading contributor to post-genomics life sciences, thus cultivating crucial trans-generational capacity and inspiration by recognizing the emerging scholars and omics systems scientists who can think and conduct science from cell to society.

  8. Proceedings of the Office of Special Education Programs' Annual Technical Assistance and Dissemination Meeting (6th, Washington, DC, January 16-18, 1996).

    ERIC Educational Resources Information Center

    Special Education Programs (ED/OSERS), Washington, DC.

    This document presents the proceedings for the Office of Special Education Programs' 6th Annual Technical Assistance and Dissemination Meeting held on January 16-18, 1996, in Washington, DC. Conference discussions centered around changing expectations for local and state education agencies and technical assistance and dissemination (TA&D)…

  9. 6(th) Annual Symposium on Self-Monitoring of Blood Glucose (SMBG) applications and beyond, April 25-27, 2013, Riga, Latvia.

    PubMed

    Alzaid, Aus; Schlaeger, Christof; Hinzmann, Rolf

    2013-12-01

    International experts in the fields of diabetes, diabetes technology, endocrinology, and pediatrics gathered for the 6(th) Annual Symposium on Self-Monitoring of Blood Glucose (SMBG) Applications and beyond. The aim of this meeting was to continue setting up a global network of experts in this field and provide an international platform for exchange of ideas to improve life for people with diabetes. The 2013 meeting comprised a comprehensive scientific program, parallel interactive workshops, and two keynote lectures. All these discussions were intended to help identify gaps and areas where further scientific work and clinical studies are warranted.

  10. 6th Annual Symposium on Self-Monitoring of Blood Glucose (SMBG) Applications and Beyond, April 25–27, 2013, Riga, Latvia

    PubMed Central

    Schlaeger, Christof; Hinzmann, Rolf

    2013-01-01

    Abstract International experts in the fields of diabetes, diabetes technology, endocrinology, and pediatrics gathered for the 6th Annual Symposium on Self-Monitoring of Blood Glucose (SMBG) Applications and beyond. The aim of this meeting was to continue setting up a global network of experts in this field and provide an international platform for exchange of ideas to improve life for people with diabetes. The 2013 meeting comprised a comprehensive scientific program, parallel interactive workshops, and two keynote lectures. All these discussions were intended to help identify gaps and areas where further scientific work and clinical studies are warranted. PMID:24074038

  11. Celebrating Partnerships. Highlights of the Annual Community Education Conference (6th, River Grove, IL, November 14, 1997).

    ERIC Educational Resources Information Center

    Solorzano, Sylvia M., Ed.

    This paper is published annually by the Celebrating Partnerships Conference Planning Committee to share information on successful partnership programs that address community issues and concerns. The papers were presented at a conference in honor of National Community Education Day. This collection illustrates the efforts of diverse community…

  12. The Annual Minority Recruitment and Retention Conference Proceedings (6th, Austin, Texas, April 4-6, 1990).

    ERIC Educational Resources Information Center

    Texas Higher Education Coordinating Board, Austin.

    The summarized proceedings of the sixth annual minority recruitment and retention conference which focused on ways to create a multicultural university are presented. Pre-Conference session and Workshop/Roundtable topics and their presenters include the following: "Managing Organizational Culture to Improve Student Achievement" (Richard…

  13. Proceedings of the Annual Mid-South Instructional Technology Conference (6th, Murfreesboro, Tennessee, April 8-10, 2001).

    ERIC Educational Resources Information Center

    Middle Tennessee State Univ., Murfreesboro.

    This proceedings of the sixth annual Mid-South Instructional Technology Conference contains the following papers: "They're Not Just Big Kids: Motivating Adult Learners" (Karen Jarrett Thoms); "A Computer Integrated Biology Laboratory Experience" (James B. Kring); "Building Web Sites for Mathematics Courses: Some Answers to…

  14. Islet cell research brings hope for a diabetes cure: meeting report from the 6(th) annual islet society meeting in Stellenbosch, South Africa.

    PubMed

    Tchokonte-Nana, V; Cockburn, I L; Manda, J K; Kotze, P C; Johnson, J D

    2014-01-01

    The International Diabetes Federation predicts that, over the next twenty years, the largest increase in the prevalence of diabetes will be in the Africa region. Recognizing an unmet need for more focus on Africa and engagement with African scholars, the Islet Society held its 6th annual meeting July 20-21, 2014 in Stellenbosch, South Africa. Here, we present a report that covers the presentations and discussion points from that meeting. Work was presented on a variety of topics and included presentations by a significant proportion of Africa diabetes researchers. Overall, it was an excellent conference, with many new international collaborations initiated. We hope that other groups will also respond to the need for more conferences in Africa and focused on Africa.

  15. 6th International Microbeam Workshop

    SciTech Connect

    Dr Kevin M. Prise

    2004-01-01

    The extended abstracts which are submitted here present a summary of the proceedings of the 6th International Workshop/12th LH Gray Workshop: Microbeam Probes of Cellular Radiation Response, held at St. Catherine's College, University of Oxford, UK on March, 29th-31st, 2003. In 1993 the 4th LH Gray Workshop entitled ''Microbeam Probes of Cellular Radiation Response'' was held at the Gray Cancer Institute in Northwood. This was organized by Prof BD Michael, Dr M. Folkard and Dr KM Prise and brought together 40 participants interested in developing and applying new microbeam technology to problems in radiation biology (1). The workshop was an undoubted success and has spawned a series of subsequent workshops every two years. In the past, these workshops have been highly successful in bringing together groups interested in developing and applying micro-irradiation techniques to the study of cell and tissue damage by ionizing radiations. Following the first microbeam workshop, there has been a rapid growth in the number of centres developing radiobiology microbeams, or planning to do so and there are currently 15-20 worldwide. Much of the recent research using microbeams has used them to study low-dose effects and ''non-targeted'' responses such bystander effects, genomic instability and adaptive responses. The goal of the 6th workshop was to build on our knowledge of the development of microbeam approaches and the application to radiation biology in the future with the meeting stretching over a 3 day period. Over 80 participants reviewed the current state of radiobiology microbeam research worldwide and reported on new technological developments both in the fields of physics and biology.

  16. Research and Education: The Foundations for Rehabilitation Service Delivery--10th Annual National Rehabilitation Educators Conference April 6th-10th, 2010

    ERIC Educational Resources Information Center

    Chou, Chih Chin

    2010-01-01

    The theme of the 10th annual National Rehabilitation Educators conference emphasized research and teaching ideals in the areas of clinical supervision, evidence-based practice in rehabilitation, rehabilitation counseling process, effective rehabilitation counseling training strategies, accreditation and licensure, rehabilitation ethics, and…

  17. Institutional Research and Creative Change. Papers from the Annual Meeting of the North East Association for Institutional Research (6th, Cooperstown, New York, October 14-16, 1979).

    ERIC Educational Resources Information Center

    North East Association for Institutional Research.

    Papers from the 1979 annual meeting of the North East Association for Institutional Research are presented. The theme of the conference was institutional research and creative change. Part One, Budget/Cost Analysis, contains papers on academic income-cost models for institutional planning, a budget incentive factor within declining enrollments,…

  18. Exploring African and Latin American Relationships: Enhancing Cooperation and Eliminating Barriers. Annual Adult Education Research Symposium Proceedings (6th, Chicago, Illinois, April 13, 1996). Revised Edition.

    ERIC Educational Resources Information Center

    Williams, LaJuana K., Ed.

    This document contains 14 papers presented at an annual symposium sponsored by Northern Illinois University's Department of Leadership and Educational Policy Studies and College of Education. First, information about the symposium's history and participants is presented. The following papers constitute the remainder of the document:…

  19. Proceedings of the Annual ONR/CADRC Decision-Support Workshop (6th), Held in Quantico, Virginia, on 8-9 Sep 2004. Interoperability

    DTIC Science & Technology

    2004-11-01

    capabilities with profound potential for providing meaningful support to military decision makers. Indeed, some systems based on these new...support capabilities. Under these conditions Marine Corps forces had to rely mostly, if not entirely, on sea-based support and sustainment operations...overwhelming data loads. In the light of these developments the Logistics Program Office of ONR considered it timely to provide an annual forum for the

  20. Proceedings of the 6th Annual Meeting for Excess Weapons Plutonium Disposition: Plutonium Packaging, Storage and Transportation and WasteTreatment, Storage and Disposal Activities

    SciTech Connect

    Jardine, L J

    2005-06-30

    The sixth annual Excess Weapons Plutonium Disposition meeting organized by Lawrence Livermore National Laboratory (LLNL) was held November 15-17, 2004, at the State Education Center (SEC), 4 Aerodromnya Drive, St. Petersburg, Russia. The meeting discussed Excess Weapons Plutonium Disposition topics for which LLNL has the US Technical Lead Organization responsibilities. The technical areas discussed included Radioactive Waste Treatment, Storage, and Disposal, and Plutonium Oxide and Plutonium Metal Packaging, Storage and Transportation and Spent Fuel Packaging, Storage and Transportation. The meeting was conducted with a conference format using technical presentations of papers with simultaneous translation into English and Russian. There were 55 Russian attendees from 16 different Russian organizations and four non-Russian attendees from the US. Forty technical presentations were made. The meeting agenda is given in Appendix B and the attendance list is in Appendix C. The 16 different Russian design, industrial sites, and scientific organizations in attendance included staff from Rosatom/Minatom, Federal Nuclear and Radiation Safety Authority of Russia (GOSATOMNADZOR, NIERA/GAN), All Russian Designing & Scientific Research Institute of Complex Power Technology (VNIPIET), Khlopin Radium Institute (KRI), A. A. Bochvar All Russian Scientific Research Institute of Inorganic Materials (VNIINM), All Russian & Design Institute of Production Engineering (VNIPIPT), Ministry of Atomic Energy of Russian Federation Specialized State Designing Institute (GSPI), State Scientific Center Research Institute of Atomic Reactors (RIAR), Siberian Chemical Combine Tomsk (SCC), Mayak PO, Mining Chemical Combine (MCC K-26), Institute of Biophysics (IBPh), Sverdlosk Scientific Research Institute of Chemical Machine Building (SNIIChM), Kurchatov Institute (KI), Institute of Physical Chemistry Russian Academy of Science (IPCh RAS) and Radon PO-Moscow. The four non-Russian attendees included

  1. 6th International Conference on Emerging Zoonoses.

    PubMed

    Kahn, R E; Morozov, I; Feldmann, H; Richt, J A

    2012-09-01

    The 6th International Conference on Emerging Zoonoses, held at Cancun, Mexico, 24-27 February 2011, offered 84 participants from 18 countries, a snapshot of current research in numerous zoonoses caused by viruses, bacteria or prions. Co-chaired by Professors Heinz Feldmann and Jürgen Richt, the conference explored 10 topics: (i) The ecology of emerging zoonotic diseases; (ii) The role of wildlife in emerging zoonoses; (iii) Cross-species transmission of zoonotic pathogens; (iv) Emerging and neglected influenza viruses; (v) Haemorrhagic fever viruses; (vi) Emerging bacterial diseases; (vii) Outbreak responses to zoonotic diseases; (viii) Food-borne zoonotic diseases; (ix) Prion diseases; and (x) Modelling and prediction of emergence of zoonoses. Human medicine, veterinary medicine and environmental challenges are viewed as a unity, which must be considered under the umbrella of 'One Health'. Several presentations attempted to integrate the insights gained from field data with mathematical models in the search for effective control measures of specific zoonoses. The overriding objective of the research presentations was to create, improve and use the tools essential to address the risk of contagions in a globalized society. In seeking to fulfil this objective, a three-step approach has often been applied: (i) use cultured cells, model and natural animal hosts and human clinical models to study infection; (ii) combine traditional histopathological and biochemical approaches with functional genomics, proteomics and computational biology; and (iii) obtain signatures of virulence and insights into mechanisms of host defense response, immune evasion and pathogenesis. This meeting review summarizes 39 of the conference presentations and mentions briefly the 16 articles in this Special Supplement, most of which were presented at the conference in earlier versions. The full affiliations of all presenters and many colleagues have been included to facilitate further inquiries

  2. Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Zimmer, Carl [New York Times

    2016-07-12

    Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

  3. Keynote Presentation: Genome Beat (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Zimmer, Carl

    2012-03-20

    Carl Zimmer, a reporter for the New York Times, speaks on "The Genome Beat," the opening keynote presentation at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

  4. 6th Amino Acid Assessment Workshop

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The focus of the 6th workshop is on lysine, arginine, and related amino acids. Functions, metabolic pathways, clinical uses, and upper tolerance intakes are emphasized in the articles that follow. Lysine is arguably the most deficient amino acid in the food supply of countries where poverty exists, ...

  5. Research in Science Education, Volume 5. Proceedings of the Annual Conference of the Australian Science Education Research Association (6th, Flinders University, Bedford Park, South Australia, May 19-21, 1975).

    ERIC Educational Resources Information Center

    Lucas, A. M., Ed.; Power, Colin, N., Ed.

    This volume contains papers presented at the sixth Annual Conference of the Australian Science Education Research Association (ASERA) held at Flinders University in May, 1975. Paper topics include: pupil learning and classroom climate, teacher structuring behavior, the Australian Science Education Project (ASEP), cognitive preference and…

  6. Techniques and Procedures in College and Adult Reading Programs; Yearbook of the Annual Meeting of the Southwest Reading Conference for Colleges and Universities (6th, Texas Christian University, December 7-8, 1956).

    ERIC Educational Resources Information Center

    Causey, Oscar S., Ed.

    The title of this volume was the theme of the sixth annual meeting of the Southwest Reading Conference for Colleges and Universities, held in December 1956. Authors of the eleven reports on successful college and adult reading programs focused on various aspects of the programs, including academic performance, program evaluation, faculty, public…

  7. Proceedings of the Annual Mechanics of Composites Review (6th),

    DTIC Science & Technology

    1981-02-01

    ADVANCED COMPOSITES AND RESINS *Processing Effect of cure cycle parameters on resin and laminate properties eTesting Deformation and fracture...Composite Material 4. Determination of the Relationship of Free Volume to Mechanical Behavior for an Epoxy System Subjected to Various Aging Histories...Investigation of Free Volume Concepts in Relation- ship to Mechanical Behavior of an Epoxy System Subjected to Various Aging Histories 8. ApplicationofEnergy

  8. Highlights of the ATS 6th Annual Convention

    NASA Astrophysics Data System (ADS)

    Breyer, Walter

    The convention began with a keynote by Michael Tubridy, the engineer in charge of the restoration of the Birr Castle Leviathan of Parsonstown. The convention then moved up to Mount Wilson, where talks were heard by Christ Plicht, Peter Abrahams, John Briggs, Don Osterbrock, Robert Ariail, Gayle Riggsbee, and Walt Breyer. Tours were made of the 100-inch and 60-inch telescopes, and observing through the 60-inch finished the day. Sunday, talks were heard by Paul O'Leary, Kevin Johnson, Eugene Rudd, E.J. Hysom, Edward Young, and Rolf Willach. Tours were made of the Hale Solar Laboratory, George Ellery Hale's home, the Huntington Library, Pasadena City College Observatory's 20-inch reflector, and Griffith Observatory's 12-inch Zeiss. On Monday, a tour was made to Mount Palomar and the 200-inch Hale Telescope.

  9. 6th International Meshing Roundtable '97

    SciTech Connect

    White, D.

    1997-09-01

    The goal of the 6th International Meshing Roundtable is to bring together researchers and developers from industry, academia, and government labs in a stimulating, open environment for the exchange of technical information related to the meshing process. In the pas~ the Roundtable has enjoyed significant participation born each of these groups from a wide variety of countries. The Roundtable will consist of technical presentations from contributed papers and abstracts, two invited speakers, and two invited panels of experts discussing topics related to the development and use of automatic mesh generation tools. In addition, this year we will feature a "Bring Your Best Mesh" competition and poster session to encourage discussion and participation from a wide variety of mesh generation tool users. The schedule and evening social events are designed to provide numerous opportunities for informal dialog. A proceedings will be published by Sandia National Laboratories and distributed at the Roundtable. In addition, papers of exceptionally high quaIity will be submitted to a special issue of the International Journal of Computational Geometry and Applications. Papers and one page abstracts were sought that present original results on the meshing process. Potential topics include but are got limited to: Unstructured triangular and tetrahedral mesh generation Unstructured quadrilateral and hexahedral mesh generation Automated blocking and structured mesh generation Mixed element meshing Surface mesh generation Geometry decomposition and clean-up techniques Geometry modification techniques related to meshing Adaptive mesh refinement and mesh quality control Mesh visualization Special purpose meshing algorithms for particular applications Theoretical or novel ideas with practical potential Technical presentations from industrial researchers.

  10. 6th International Immunoglobulin Symposium: poster presentations.

    PubMed

    Fernandez-Cruz, E; Kaveri, S V; Peter, H-H; Durandy, A; Cantoni, N; Quinti, I; Sorensen, R; Bussel, J B; Danieli, M G; Winkelmann, A; Bayry, J; Käsermann, F; Späth, P; Helbert, M; Salama, A; van Schaik, I N; Yuki, N

    2009-12-01

    The posters presented at the 6th International Immunoglobulin Symposium covered a wide range of fields and included both basic science and clinical research. From the abstracts accepted for poster presentation, 12 abstracts were selected for oral presentations in three parallel sessions on immunodeficiencies, autoimmunity and basic research. The immunodeficiency presentations dealt with novel, rare class-switch recombination (CSR) deficiencies, attenuation of adverse events following IVIg treatment, association of immunoglobulin (Ig)G trough levels and protection against acute infection in patients with X-linked agammaglobulinaemia (XLA) and common variable immunodeficiency (CVID), and the reduction of class-switched memory B cells in patients with specific antibody deficiency (SAD). The impact of intravenous immunoglobulin on fetal alloimmune thrombocytopenia, pregnancy and postpartum-related relapses in multiple sclerosis and refractory myositis, as well as experiences with subcutaneous immunoglobulin in patients with multi-focal motor neuropathy, were the topics presented in the autoimmunity session. The interaction of dendritic cell (DC)-SIGN and alpha2,6-sialylated IgG Fc and its impact on human DCs, the enrichment of sialylated IgG in plasma-derived IgG, as wells as prion surveillance and monitoring of anti-measles titres in immunoglobulin products, were covered in the basic science session. In summary, the presentations illustrated the breadth of immunoglobulin therapy usage and highlighted the progress that is being made in diverse areas of basic and clinical research, extending our understanding of the mechanisms of immunoglobulin action and contributing to improved patient care.

  11. The Sunflower Genome and its Evolution (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Rieseberg, Loren [University of British Columbia

    2016-07-12

    Loren Rieseberg from the University of British Columbia on "The Sunflower Genome and its Evolution" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  12. Genomics of Climate Resilience (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Bermingham, Eldredge

    2013-03-27

    Eldredge Bermingham of the Smithsonian Tropical Research Institute-Panama on "Genomics of climate resilience" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  13. The Sunflower Genome and its Evolution (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Rieseberg, Loren

    2012-03-21

    Loren Rieseberg from the University of British Columbia on "The Sunflower Genome and its Evolution" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  14. Using Genomics to Dissect Seed Development (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment Meeting)

    SciTech Connect

    Goldberg, Robert

    2012-03-21

    Robert Goldberg of UCLA presents "Using Genomics to Dissect Seed Development" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  15. Using Genomics to Dissect Seed Development (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment Meeting)

    ScienceCinema

    Goldberg, Robert [UCLA

    2016-07-12

    Robert Goldberg of UCLA presents "Using Genomics to Dissect Seed Development" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  16. Student Solutions Manual to accompany Physics, 6th Edition

    NASA Astrophysics Data System (ADS)

    Cutnell, John D.; Johnson, Kenneth W.

    2003-07-01

    Work more effectively and check solutions as you go along with the text! Written by the authors, this indispensable Student Solutions Manual provides complete worked-out solutions to 25% of the end-of-chapter problems in Cutnell & Johnson's Physics, 6th Edition. These problems are specifically indicated in the text. For the 6th Edition of their best-selling Physics, the authors have added both print and online material to encourage readers to engage in the material more interactively. Physics research clearly shows that active learning is much more effective than passive learning. The 6th edition helps readers understand the interrelationships among basic physics concepts and how they fit together to describe our physical world. Throughout the text, the authors emphasize the relevance of physics to our everyday lives.

  17. Environmental Problem Perception of 6th Grade Students

    ERIC Educational Resources Information Center

    Genc, Murat; Genc, Tulin; Ergenc, Mustafa; Erkuz, Neslihan

    2016-01-01

    This study aims to examine and compare the 6th grade students' perception of environmental issues through different techniques. For this purpose, we have tried to establish the students' perception of environmental issues by studying the pictures they drew and the written texts they wrote. In this study, where we have conducted with 62 students in…

  18. The 6th International Earth Science Olympiad: A Student Perspective

    ERIC Educational Resources Information Center

    Barlett, Luke; Cathro, Darcy; Mellow, Maddi; Tate, Clara

    2014-01-01

    In October 2012, two students from the Australian Science and Mathematics School and two from Yankalilla Area School were selected to travel to Olavarria, Argentina in order to compete in the 6th International Earth Science Olympiad (IESO). It was an opportunity for individuals with a passion for Earth science to come together from 17 countries to…

  19. Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop.

    PubMed

    Van Etten, Richard A; Mauro, Michael; Radich, Jerald P; Goldman, John M; Saglio, Giuseppe; Jamieson, Catriona; Soverini, Simona; Gambacorti-Passerini, Carlo; Hehlmann, Rüdiger; Martinelli, Giovanni; Perrotti, Danilo; Scadden, David T; Skorski, Tomasz; Tefferi, Ayalew; Mughal, Tariq I

    2013-06-01

    Following the 53rd annual meeting of the American Society of Hematology (ASH) in San Diego in December 2011, a group of clinical and laboratory investigators convened for the 6th Post-ASH International Workshop on Chronic Myeloid Leukemia (CML) and Myeloproliferative Neoplasms (MPN). The Workshop took place on 13-14 December at the Estancia, La Jolla, California, USA. This report summarizes the most recent advances in the biology and therapy of CML that were presented at the ASH meeting and discussed at the Workshop. Preclinical studies focused on the CML stem cell and its niche, and on early results of deep sequencing of CML genomes. Clinical advances include updates on second- and third-generation tyrosine kinase inhibitors (TKIs), molecular monitoring, TKI discontinuation studies and new therapeutic agents. A report summarizing the pertinent advances in MPN has been published separately.

  20. Conference Report: The 6th International Symposium on Waterborne Pathogens

    EPA Pesticide Factsheets

    A review of current literature on the occurrence of waterborne pathogens in DW systems.This dataset is associated with the following publication:Rochelle, P., P. Klonicki, G. DiGiovanni, V. Hill, Y. Akagi, and E. Villegas. Conference Report: The 6th International Symposium on Waterborne Pathogens ISWP 2015. JOURNAL OF THE AMERICAN WATER WORKS ASSOCIATION. American Water Works Association, Denver, CO, USA, 107(10): 24-32, (2015).

  1. Benign recurrent abducens (6th) nerve palsy in two children.

    PubMed

    Knapp, Christopher M; Gottlob, Irene

    2004-03-01

    Benign recurrent abducens (6th) nerve palsy is rare. We found 23 cases in children reported in the literature; however, many of these cases followed immunization or were associated with viral illness. Here we report two cases of recurrent abducens nerve palsy with no obvious etiology. The diagnosis should be considered in any child who experiences abducens nerve palsy in the absence of any underlying pathology or precipitating factors.

  2. The Challenges and Opportunities for Extending Plant Genomics to Climate (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Weston, David

    2013-03-01

    David Weston of Oak Ridge National Laboratory on "The challenges and opportunities for extending plant genomics to climate" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  3. Genomic Analysis of Natural Variation for Seed and Plant Size in Maize ( JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Kaeppler, Shawn

    2012-03-21

    Shawn Kaeppler from the University of Wisconsin-Madison on "Genomic Analysis of Biofuel Traits in Maize and Switchgrass" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif

  4. New Approaches and Technologies to Sequence de novo Plant reference Genomes (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Schmutz, Jeremy

    2013-03-01

    Jeremy Schmutz of the HudsonAlpha Institute for Biotechnology on "New approaches and technologies to sequence de novo plant reference genomes" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  5. The Genome of Selaginella: A Remnant of an Ancient Vascular Plant Lineage (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    ScienceCinema

    Banks, Jody [Purdue University

    2016-07-12

    Jody Banks from Purdue University on "The Genome of Selaginella, a Remnant of an Ancient Vascular Plant Lineage" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif.

  6. Genomic Analysis of Natural Variation for Seed and Plant Size in Maize ( JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Kaeppler, Shawn [University of Wisconsin, Madison

    2016-07-12

    Shawn Kaeppler from the University of Wisconsin-Madison on "Genomic Analysis of Biofuel Traits in Maize and Switchgrass" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif

  7. The Genome of Selaginella: A Remnant of an Ancient Vascular Plant Lineage (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    SciTech Connect

    Banks, Jody

    2012-03-21

    Jody Banks from Purdue University on "The Genome of Selaginella, a Remnant of an Ancient Vascular Plant Lineage" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif.

  8. 6th ESO/OHP Summer School in Astrophysical Observations

    NASA Astrophysics Data System (ADS)

    Véron, M.-P.; Meylan, G.

    1998-09-01

    The 6th ESO/OHP Summer School was hosted again at the Observatoire de Haute-Provence (OHP) from 15 to 25 July 1998. The school, held only every second years, selects 18 of Europe's most promising young doctoral students in astronomy. Courses of lectures, observations, and analysis form the intellectual menu which is aimed at teaching the process of extracting astrophysically digestible results from the photons harvested at the telescopes, such as the ESO VLT, whose four telescopes will become available to the community in turn during the next few years.

  9. Low Dimensional Dynamics in the Crayfish 6th Ganglion

    NASA Astrophysics Data System (ADS)

    Pei, Xing; Moss, Frank

    1996-03-01

    Finding low dimensional dynamical behavior in biological preparations has received much attention. Neurons are, however, subject to random processes, or "noise". Thus specific dynamical behavior is evidenced by well defined signatures embedded in noisy data files(D. Pierson and F. Moss Phys. Rev. Lett. 75, 2124 (1995)). We report the results of a statistical search for unstable periodic orbits in the periodically stimulated 6th ganglion of the crayfish Procambarus clarkii. Electrophysiological recordings from the caudal photoreceptor neuron within the ganglion provide the data. We discuss the results in terms of the cyclic theory of chaos.

  10. 6th Japan Bioanalysis Forum Symposium: challenge of regulated bioanalysis.

    PubMed

    Igarashi, Harue

    2015-01-01

    Biomarker measurement and LC-MS analysis of large molecule pharmaceuticals (LM-MS) are becoming increasingly important in pharmaceutical development, although they are not included in the existing bioanalytical method validation guidelines in Japan. The 6th Japan Bioanalysis Forum symposium presented challenges regarding biomarkers and LM-MS, as well as the current circumstances for regulated bioanalysis, by inviting speakers from Japan, the USA, European Union and Asia-pacific. Japan Bioanalysis Forum discussion groups also presented their outcomes and openly discussed these with the attendees - over 200 dedicated individuals from industry, regulatory agencies and academia. The symposium successfully reinforced the idea that fit-for-purpose approaches are necessary, and that science should drive any judgments and actions throughout drug development.

  11. Genome-wide investigation reveals high evolutionary rates in annual model plants

    PubMed Central

    2010-01-01

    Background Rates of molecular evolution vary widely among species. While significant deviations from molecular clock have been found in many taxa, effects of life histories on molecular evolution are not fully understood. In plants, annual/perennial life history traits have long been suspected to influence the evolutionary rates at the molecular level. To date, however, the number of genes investigated on this subject is limited and the conclusions are mixed. To evaluate the possible heterogeneity in evolutionary rates between annual and perennial plants at the genomic level, we investigated 85 nuclear housekeeping genes, 10 non-housekeeping families, and 34 chloroplast genes using the genomic data from model plants including Arabidopsis thaliana and Medicago truncatula for annuals and grape (Vitis vinifera) and popular (Populus trichocarpa) for perennials. Results According to the cross-comparisons among the four species, 74-82% of the nuclear genes and 71-97% of the chloroplast genes suggested higher rates of molecular evolution in the two annuals than those in the two perennials. The significant heterogeneity in evolutionary rate between annuals and perennials was consistently found both in nonsynonymous sites and synonymous sites. While a linear correlation of evolutionary rates in orthologous genes between species was observed in nonsynonymous sites, the correlation was weak or invisible in synonymous sites. This tendency was clearer in nuclear genes than in chloroplast genes, in which the overall evolutionary rate was small. The slope of the regression line was consistently lower than unity, further confirming the higher evolutionary rate in annuals at the genomic level. Conclusions The higher evolutionary rate in annuals than in perennials appears to be a universal phenomenon both in nuclear and chloroplast genomes in the four dicot model plants we investigated. Therefore, such heterogeneity in evolutionary rate should result from factors that have genome

  12. Fundamentals of Physics, 6th Edition Enhanced Problems Version

    NASA Astrophysics Data System (ADS)

    Halliday, David; Resnick, Robert; Walker, Jearl

    2002-04-01

    No other text on the market today can match the success of Halliday, Resnick and Walker's Fundamentals of Physics. This text continues to outperform the competition year after year, and the new edition will be no exception. Intended for Calculus-based Physics courses, the 6th edition of this extraordinary text is a major redesign of the best-selling 5th edition, which still maintains many of the elements that led to its enormous success. Jearl Walker adds his unique style to this edition with the addition of new problems designed to capture, and keep, students' attention. Nearly all changes are based on suggestions from instructors and students using the 5th edition, from reviewer comments, and from research done on the process of learning. The primary goal of this text is to provide students with a solid understanding of fundamental physics concepts, and to help them apply this conceptual understanding to quantitative problem solving. The principal goal of Halliday-Resnick-Walker is to provide instructors with a tool by which they can teach students how to effectively read scientific material and successfully reason through scientific questions. To sharpen this tool, the Enhanced Problems Version of the sixth edition of Fundamentals of Physics contains over 1000 new, high-quality problems that require thought and reasoning rather than simplistic plugging of data into formulas.

  13. PREFACE: 6th EEIGM International Conference on Advanced Materials Research

    NASA Astrophysics Data System (ADS)

    Horwat, David; Ayadi, Zoubir; Jamart, Brigitte

    2012-02-01

    The 6th EEIGM Conference on Advanced Materials Research (AMR 2011) was held at the European School of Materials Engineering (EEIGM) on the 7-8 November 2011 in Nancy, France. This biennial conference organized by the EEIGM is a wonderful opportunity for all scientists involved in the EEIGM programme, in the 'Erasmus Mundus' Advanced Materials Science and Engineering Master programme (AMASE) and the 'Erasmus Mundus' Doctoral Programme in Materials Science and Engineering (DocMASE), to present their research in the various fields of Materials Science and Engineering. This conference is also open to other universities who have strong links with the EEIGM and provides a forum for the exchange of ideas, co-operation and future orientations by means of regular presentations, posters and a round-table discussion. This edition of the conference included a round-table discussion on composite materials within the Interreg IVA project '+Composite'. Following the publication of the proceedings of AMR 2009 in Volume 5 of this journal, it is with great pleasure that we present this selection of articles to the readers of IOP Conference Series: Materials Science and Engineering. Once again it represents the interdisciplinary nature of Materials Science and Engineering, covering basic and applicative research on organic and composite materials, metallic materials and ceramics, and characterization methods. The editors are indebted to all the reviewers for reviewing the papers at very short notice. Special thanks are offered to the sponsors of the conference including EEIGM-Université de Lorraine, AMASE, DocMASE, Grand Nancy, Ville de Nancy, Region Lorraine, Fédération Jacques Villermaux, Conseil Général de Meurthe et Moselle, Casden and '+Composite'. Zoubir Ayadi, David Horwat and Brigitte Jamart

  14. Genome-Scale Discovery of Cell Wall Biosynthesis Genes in Populus (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Muchero, Wellington [Oak Ridge National Laboratory

    2016-07-12

    Wellington Muchero from Oak Ridge National Laboratory gives a talk titled "Discovery of Cell Wall Biosynthesis Genes in Populus" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  15. The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis.

    PubMed

    Paulissen, Sandra M J; van Hamburg, Jan Piet; Dankers, Wendy; Lubberts, Erik

    2015-07-01

    The IL-17A producing T-helper-17 (Th17) cell population plays a major role in rheumatoid arthritis (RA) pathogenesis and has gained wide interest as treatment target. IL-17A expressing Th cells are characterized by the expression of the chemokine receptor CCR6 and the transcription factor RORC. In RA, CCR6+ Th cells were identified in peripheral blood, synovial fluid and inflamed synovial tissue. CCR6+ Th cells might drive the progression of an early inflammation towards a persistent arthritis. The CCR6+ Th cell population is heterogeneous and several subpopulations can be distinguished, including Th17, Th22, Th17.1 (also called non-classic Th1 cells), and unclassified or intermediate populations. Interestingly, some of these populations produce low levels of IL-17A but are still very pathogenic. Furthermore, the CCR6+ Th cells phenotype is unstable and plasticity exists between CCR6+ Th cells and T-regulatory (Treg) cells and within the CCR6+ Th cell subpopulations. In this review, characteristics of the different CCR6+ Th cell populations, their plasticity, and their potential impact on rheumatoid arthritis are discussed. Moreover, current approaches to target CCR6+ Th cells and future directions of research to find specific CCR6+ Th cell targets in the treatment of patients with RA and other CCR6+ Th cell mediated autoimmune diseases are highlighted.

  16. Proceedings of the 6th European VLBI Network Symposium

    NASA Astrophysics Data System (ADS)

    Ros, Eduardo; Porcas, Richard W.; Lobanov, Andrei P.; Zensus, J. Anton

    This volume contains the papers presented at the 6th Symposium of the European VLBI Network, held in Bonn on 25-28 June 2002. The initial aim of these biennial gatherings of European VLBI practitioners was to review in a timely manner new results and technical developments related to Very Long Baseline Interferometry. Now, however, interest and participation in the EVN Symposia reaches far beyond Europe, reflecting the fact that scientific research and development programs are carried out to a high degree in international and often truly global collaborations. More than 120 scientists from around the world registered for participation in the Symposium. The Symposium was hosted by the Max-Planck-Institut für Radioastronomie and was held at the Gustav Stresemann Institut. In addition to the scientific sessions and poster presentations, the program included an EVN Users Meeting, an MPIfR versus Rest-of-the-World football match (highly appropriate given the competing World Cup event!), a visit to the MPIfR's 100m radio telescope in Effelsberg, and a Conference Dinner held in the nearby old walled town of Bad Müunstereifel. To maximize the usefulness of these proceedings (and possibly as a daring precedent) the Editors decided to demand the written versions of talks and posters and to complete the editorial work before the meeting, and to deliver the book to the participants at the beginning of the Symposium. We thank the authors for their cooperation in delivering publication-ready electronic manuscripts and for meeting the strict deadlines. It is highly gratifying that only a handful of the 100 presentations are not represented in this volume. The editors have made minor changes to some of the contributions in order to improve readability, and take responsibility for any errors arising from these changes. Besides the authors, many individuals have contributed to the preparation of the meeting and its proceedings. In addition to many members of the MPIfR staff, we

  17. Genomic variation in a global village: report of the 10th annual Human Genome Variation Meeting 2008.

    PubMed

    Brookes, Anthony J; Chanock, Stephen J; Hudson, Thomas J; Peltonen, Leena; Abecasis, Gonçalo; Kwok, Pui-Yan; Scherer, Stephen W

    2009-07-01

    The Centre for Applied Genomics of the Hospital for Sick Children and the University of Toronto hosted the 10th Human Genome Variation (HGV) Meeting in Toronto, Canada, in October 2008, welcoming about 240 registrants from 34 countries. During the 3 days of plenary workshops, keynote address, and poster sessions, a strong cross-disciplinary trend was evident, integrating expertise from technology and computation, through biology and medicine, to ethics and law. Single nucleotide polymorphisms (SNPs) as well as the larger copy number variants (CNVs) are recognized by ever-improving array and next-generation sequencing technologies, and the data are being incorporated into studies that are increasingly genome-wide as well as global in scope. A greater challenge is to convert data to information, through databases, and to use the information for greater understanding of human variation. In the wake of publications of the first individual genome sequences, an inaugural public forum provided the opportunity to debate whether we are ready for personalized medicine through direct-to-consumer testing. The HGV meetings foster collaboration, and fruits of the interactions from 2008 are anticipated for the 11th annual meeting in September 2009.

  18. Genomic Variation in a Global Village: Report of the 10th Annual Human Genome Variation Meeting 2008

    PubMed Central

    Brookes, Anthony J.; Chanock, Stephen J.; Hudson, Thomas J.; Peltonen, Leena; Abecasis, Gonçalo; Kwok, Pui-Yan; Scherer, Stephen W.

    2013-01-01

    The Centre for Applied Genomics of the Hospital for Sick Children and the University of Toronto hosted the 10th Human Genome Variation (HGV) Meeting in Toronto, Canada, in October 2008, welcoming about 240 registrants from 34 countries. During the 3 days of plenary workshops, keynote address, and poster sessions, a strong cross-disciplinary trend was evident, integrating expertise from technology and computation, through biology and medicine, to ethics and law. Single nucleotide polymorphisms (SNPs) as well as the larger copy number variants (CNVs) are recognized by ever-improving array and next-generation sequencing technologies, and the data are being incorporated into studies that are increasingly genome-wide as well as global in scope. A greater challenge is to convert data to information, through databases, and to use the information for greater understanding of human variation. In the wake of publications of the first individual genome sequences, an inaugural public forum provided the opportunity to debate whether we are ready for personalized medicine through direct-to-consumer testing. The HGV meetings foster collaboration, and fruits of the interactions from 2008 are anticipated for the 11th annual meeting in September 2009. PMID:19384970

  19. CyanoGEBA: A Better Understanding of Cynobacterial Diversity through Large-scale Genomics (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Shih, Patrick [Kerfeld Lab, UC Berkeley and JGI

    2016-07-12

    Patrick Shih, representing both the University of California, Berkeley and JGI, gives a talk titled "CyanoGEBA: A Better Understanding of Cynobacterial Diversity through Large-scale Genomics" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  20. Omics in the Arctic: Genome-enabled Contributions to Carbon Cycle Research in High-Latitude Ecosystems (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Wullschleger, Stan [ORNL

    2016-07-12

    Stan Wullschleger of Oak Ridge National Laboratory on "Omics in the Arctic: Genome-enabled Contributions to Carbon Cycle Research in High-Latitude Ecosystems" on March 22, 2012 at the 7th Annual Genomics of Energy & Environment Meeting in Walnut Creek, California.

  1. Applications of Genome-based Science in Shaping Citrus Industries of the World (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    SciTech Connect

    Gmitter Jr, Fred

    2012-03-21

    Fred Gmitter from the University of Florida on "Applications of Genome-based Science in Shaping the Future of the World's Citrus Industries" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  2. Applications of Genome-based Science in Shaping Citrus Industries of the World (JGI Seventh Annual User Meeting, 2012: Genomics of Energy and Environment)

    ScienceCinema

    Gmitter Jr, Fred [University of Florida

    2016-07-12

    Fred Gmitter from the University of Florida on "Applications of Genome-based Science in Shaping the Future of the World's Citrus Industries" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  3. Omics in the Arctic: Genome-enabled Contributions to Carbon Cycle Research in High-Latitude Ecosystems (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Wullschleger, Stan

    2012-03-22

    Stan Wullschleger of Oak Ridge National Laboratory on "Omics in the Arctic: Genome-enabled Contributions to Carbon Cycle Research in High-Latitude Ecosystems" on March 22, 2012 at the 7th Annual Genomics of Energy & Environment Meeting in Walnut Creek, California.

  4. Introducing National Center for Genome Resources (NCGR) Informatics (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema

    Crow, John [National Center for Genome Resources

    2016-07-12

    John Crow from the National Center for Genome Resources discusses his organization's informatics at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  5. Nearly Finished Genomes Produced Using Gel Microdroplet Culturing (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema

    Fitzsimmons, Michael [LANL

    2016-07-12

    Michael Fitzsimmons from Los Alamos National Laboratory gives a talk titled "Nearly Finished Genomes Produced Using Gel Microdroplet Culturing" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  6. Reprogramming Bacteria to Seek and Destroy Small Molecules (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Gallivan, Justin [Emory University

    2016-07-12

    Justin Gallivan, of Emory University presents a talk titled "Reprogramming Bacteria to Seek and Destroy Small Molecules" at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif

  7. Improving biofuel feedstocks by modifying xylan biosynthesis (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Lau, Jane

    2013-03-01

    Jane Lau of the Joint BioEnergy Institute on "Improving biofuel feedstocks by modifying xylan biosynthesis" at the 8th Annual Genomics of Energy & Environment Meeting on March 28, 2013 in Walnut Creek, Calif.

  8. Reprogramming Bacteria to Seek and Destroy Small Molecules (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Gallivan, Justin

    2012-03-21

    Justin Gallivan, of Emory University presents a talk titled "Reprogramming Bacteria to Seek and Destroy Small Molecules" at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, Calif

  9. Regulation of Flowering in Brachypodium distachyon (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Amasino, Rick

    2013-03-01

    Rick Amasino of the University of Wisconsin on "Regulation of Flowering in Brachypodium distachyon" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  10. Introducing National Center for Genome Resources (NCGR) Informatics (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect

    Crow, John

    2012-06-01

    John Crow from the National Center for Genome Resources discusses his organization's informatics at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  11. PMI: Plant-Microbe Interfaces (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Schadt, Christopher

    2013-03-01

    Christopher Schadt of Oak Ridge National Laboratory on "Plant-Microbe Interactions" in the context of poplar trees at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 held in Walnut Creek, Calif.

  12. PREFACE: The 6th Nordic Meeting on Nuclear Physics

    NASA Astrophysics Data System (ADS)

    Løvhøiden, G.; Thorsteinsen, T. F.; Vaagen, J. S.

    1990-01-01

    After an unintended time gap of five years, the series of regular Nordic meetings on nuclear physics was continued with the 6th Nordic Meeting, August 10-15, 1989. The site was Utgarden in the outskirts of Kopervik, the administration center for the Saga island of Karmøy on the west-coast of Norway. Utgarden, a "peoples high-school'' with a kitchen, housing facility and a neighboring modern gymnasium with fine lecture halls, proved to be an inexpensive and adequate site for the meeting. From the time of the Vikings, the sound between Karmøyy and the mainland has been a vital part of the way to the north. Mobility and international orientation is still a signature of an area where today essential parts of Norway's oil- and metal industry are located. The conference program included a session on nuclear physics in industry and society, with contributed talks from a number of companies and technology/research institutions, which also sponsored the meeting. Lunch visits to Hydro's aluminium plant on Karmøy or alternatively to Statoil's gas terminal on the mainland, were included in the program. The scientific program gives a cross section of nuclear physics activities in which researchers from the Nordic countries are involved nowadays. The spectrum is rich, and the emphasis has shifted to higher energies than was the case five years ago. We appreciate the possibility to present this overview in a separate volume of Physica Scripta. The present issue covers nearly all the talks given at the meeting. The order deviates, however, somewhat from that of the conference program. The organizing committee tried to encourage in various ways the participation of young physicists; this effort was truely rewarded. The young participants put their imprint on the activities in the lecture halls and even more on the soccer arena. The meeting was sponsored by The University of Bergen, The Nordic Accelerator Committee, NORDITA, The Norwegian Research Council for Science and the

  13. Genomics Encyclopedia of Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB): a resource for microsymbiont genomes (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Reeve, Wayne

    2013-03-01

    Wayne Reeve of Murdoch University on "Genomics Encyclopedia of Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB): a resource for microsymbiont genomes" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  14. Understanding Historical Human Migration Patterns and Interbreeding (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Willerslev, Eske [University of Copenhagen

    2016-07-12

    Eske Willerslev from the University of Copenhagen on "Understanding Historical Human Migration Patterns and Interbreeding Using the Ancient Genomes of a Palaeo-Eskimo and an Aboriginal Australian" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  15. Significant changes in the 6th edition of FACT-JACIE standards affecting apheresis facilities.

    PubMed

    Schwartz, Joseph

    2017-02-01

    FACT-JACIE cellular therapy standards are being revised every 3years and currently in their 6th edition. Significant changes in the 6th edition of the standards that affect apheresis facilities participating in cellular therapy product collections are presented.

  16. 169. GENERAL VIEW DOWN 6TH AVE. VIEW TO SOUTHWEST DOWN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    169. GENERAL VIEW DOWN 6TH AVE. VIEW TO SOUTHWEST DOWN 6TH AVE. SHOWING FROM LEFT TO RIGHT, BUILDING 8 (HOSPITAL) WITH PART OF ONE OF ITS 1-STORY WARD WINGS, AND THE 3 ORIGINAL DORMITORY WINGS OF BUILDING 9 (BOQ). - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

  17. The Fifth Annual Sc2.0 and Synthetic Genomes Conference: Synthetic Genomes in High Gear.

    PubMed

    Walker, Roy S K; Cai, Yizhi

    2016-09-16

    The Sc2.0 project is perhaps the largest synthetic biology project in the public domain, and ultimately aims to construct a new version of the humble brewer's yeast, Saccharomyces cerevisiae. Each year, the Sc2.0 consortium gather to discuss progress in this ambitious project and highlight new developments at the forefront of synthetic genome engineering. This viewpoint summarizes some of the key moments of the 2016 conference, including updates on the Sc2.0 project itself, mammalian synthetic biology, DNA assembly automation, HGP-Write and a panel discussion on the social and ethical perspectives of synthetic biology.

  18. Prevention and Treatment of Cancer: Hypes and Hopes 6th International Translational Cancer Research Conference.

    PubMed

    Patel, Prabhudas; Vora, Hemangini; Aggarwal, Bharat B; Gandhi, Varsha; Mehta, Kapil; Pathak, Sen

    2016-09-01

    Cancer is primarily an "old-age" disease that has an "age-old" history. The overall incidence of cancer is much higher in Western countries, but is rapidly growing in Eastern countries perhaps due to change in life-style. Almost three million studies published to date indicate that cancer is a hyperproliferative disorder that arises from dysregulation of multiple cell signaling pathways. The cancer genome landscape indicates that approximately 140 genes and 12 cell signaling pathways drive almost all cancers. "Targeted therapy," a buzz word in cancer treatment for the past two decades, has provided antibodies, as well as small-molecule inhibitors. These therapies have been successful only in few instances. However, in most cases, minor increase in overall survival has been reported at the cost of huge expense. An alternative strategy is to prevent cancer or to diagnose and treat the disease at an early stage to gain survival benefits. Such interventions are also cost-effective. To address some of these issues, the 6th International Translational Cancer Research Conference was held during February 4-7th, 2016, in Ahmedabad, Gujarat, India; the homeland of Mahatma Gandhi. This conference was focused on utilizing multidisciplinary approaches for prevention and early treatment that would likely simultaneously or sequentially target many key pathways. Several distinguished speakers were invited from around the world. This article highlights primary features of this conference.

  19. Genomic Speciation and Adaptation in Aquilegia (2011 JGI User Meeting)

    SciTech Connect

    Hodges, Scott

    2011-03-23

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Scott Hodges of the University of California, Santa Barbara gives a presentation on "Genomic Speciation and Adaptation in Aquilegia" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  20. Genomics of Extinct and Endangered Species (2011 JGI User Meeting)

    ScienceCinema

    Shuster, Stephen [Penn State University

    2016-07-12

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Stephen Shuster of Penn State University gives a presentation on "Genomics of Extinct and Endangered Species" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  1. Genomics of Extinct and Endangered Species (2011 JGI User Meeting)

    SciTech Connect

    Shuster, Stephen

    2011-03-23

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Stephen Shuster of Penn State University gives a presentation on "Genomics of Extinct and Endangered Species" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  2. Genomic Speciation and Adaptation in Aquilegia (2011 JGI User Meeting)

    ScienceCinema

    Hodges, Scott [University of California, Santa Barbara

    2016-07-12

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Scott Hodges of the University of California, Santa Barbara gives a presentation on "Genomic Speciation and Adaptation in Aquilegia" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  3. Soldering Technology (6th) Proceedings of Annual Seminar, 17-18 February 1982.

    DTIC Science & Technology

    1982-02-01

    hot air knife, the preheater and the solder wave at a fixed incline of 40 to achieve the optimum rela- tionship with the solder wave shape. Our design...transport IQ SCREW CHANqMD F .. Y- fingers contact the card edges along 50% of the length on both sides (1/4" grip length, 1/4" air repetitiously). Two... AIR SPU MANIFOLD- (or de-activated) in 4-inch increments to conform more closely to the width of the circuit board. Each chamber has its

  4. Proceedings of the Annual Conference on Environmental Toxicology (6th), 21-23 October 1975

    DTIC Science & Technology

    1975-12-01

    Research Triangle Institute for chemical analyses , Dr. J. L . Williams of Becton, Dickinson Re- search Center and Dr. D. Swift of Johns Hopkins University...MORPHOLOGICAL METHODS FOR EVALUATION OF PULMONARY TOXICITY IN ANIMALS ............ 27 D. L . Dungworth 2 - PULMONARY FUNCTION METHODS FOR...193 D. L . Pollard 10 - TOXIC HAZARD EVALUATION BY MASS SPECTROMETRIC THERMAL ANALYSIS ........ .............. 199 Gerd A. Kleineberg

  5. Proceedings of the 6th Annual Summer Conference: NASA/USRA University Advanced Design Program

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The NASA/USRA University Advanced Design Program is a unique program that brings together NASA engineers, students, and faculty from United States engineering schools by integrating current and future NASA space/aeronautics engineering design projects into the university curriculum. The Program was conceived in the fall of 1984 as a pilot project to foster engineering design education in the universities and to supplement NASA's in-house efforts in advanced planning for space and aeronautics design. Nine universities and five NASA centers participated in the first year of the pilot project. The study topics cover a broad range of potential space and aeronautics projects that could be undertaken during a 20 to 30 year period beginning with the deployment of the Space Station Freedom scheduled for the mid-1990s. Both manned and unmanned endeavors are embraced, and the systems approach to the design problem is emphasized.

  6. 3. BUILDING 522, EAST SIDE, FROM ACROSS 6TH STREET AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. BUILDING 522, EAST SIDE, FROM ACROSS 6TH STREET AT ITS INTERSECTION WITH G STREET, LOOKING NORTHWEST. - Oakland Naval Supply Center, Aeronautical Materials Storehouses, Between E & G Streets, between Fourth & Sixth Streets, Oakland, Alameda County, CA

  7. Conference summary: 6th International conference on hyperons, charm, and beauty hadrons (BEACH04)

    SciTech Connect

    Butler, Joel N.; /Fermilab

    2004-12-01

    The 6th International Conference on Hyperons, Charm, and Beauty Hadrons (BEACH04) treated us to a wonderful array of new results. Here the author attempts to summarize the talks and discuss the conference highlights.

  8. Annual genome conference. Final report, September 1, 1994--August 31, 1995

    SciTech Connect

    Gardiner, K.

    1995-11-01

    Tremendous progress has been made in the construction of physical and genetic maps of the human chromosomes. The next step in the solving of disease related problems, and in understanding the human genome as a whole, is the systematic isolation of transcribed sequences. Many investigators have already embarked upon comprehensive gene searches, and many more are considering the best strategies for undertaking such searches. Because these are likely to be costly and time consuming endeavors, it is important to determine the most efficient approaches. As a result, it is critical that investigators involved in the construction of transcriptional maps have the opportunity to discuss their experiences and their successes with both old and new technologies. This document contains the proceedings of the Fourth Annual Workshop on the Identification of Transcribed Sequences, held in Montreal, Quebec, October 16-18, 1994. Included are the workshop notebook, containing the agenda, abstracts presented and list of attendees. Topics included: Progress in the application of the hybridization based approaches and exon trapping; Progress in transcriptional map construction of selected genomic regions; Computer assisted analysis of genomic and protein coding sequences and additional new approaches; and, Sequencing and mapping of random cDNAs.

  9. Closing Keynote Presentation on the Genomics of Energy and the Environment (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Benner, Stephen

    2012-03-22

    Steve Benner, a distinguished chemist at the Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology, provides the closing keynote address for the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  10. Closing Keynote Presentation on the Genomics of Energy and the Environment (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Benner, Stephen [Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology

    2016-07-12

    Steve Benner, a distinguished chemist at the Foundation for Applied Molecular Evolution, Westheimer Institute of Science and Technology, provides the closing keynote address for the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  11. Getting to the Root of Things: Spatiotemporal Regulatory Networks (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Brady, Siobhan [UC Davis

    2016-07-12

    Siobhan Brady from University of California, Davis, gives a talk titled "tGetting to the Root of things: Spatiotemporal Regulatory Networks" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  12. Tapping the Molecular Potential of Microalgae to Produce Biomass (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Sayre, Richard [LANL

    2016-07-12

    Richard Sayre, from Los Alamos National Laboratory, presents a talk titled "Tapping the Molecular Potential of Microalgae to Produce Biomass" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  13. Genomic and Systems Biology Analyses of Social Behavior or Evolutionary Genomic Analyses of Insect Society: Eat, Drink, and Be Scary (2011 JGI User Meeting)

    ScienceCinema

    Robinson, Gene

    2016-07-12

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Gene Robinson of the University of Illinois on "Genomic and Systems Biology Analyses of Social Behavior" at the 6th Annual Genomics of Energy & Environment Meeting on March 23, 2011

  14. Genomic and Systems Biology Analyses of Social Behavior or Evolutionary Genomic Analyses of Insect Society: Eat, Drink, and Be Scary (2011 JGI User Meeting)

    SciTech Connect

    Robinson, Gene

    2011-03-23

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Gene Robinson of the University of Illinois on "Genomic and Systems Biology Analyses of Social Behavior" at the 6th Annual Genomics of Energy & Environment Meeting on March 23, 2011

  15. Genome sequence of Ensifer medicae strain WSM1369; an effective microsymbiont of the annual legume Medicago sphaerocarpos.

    PubMed

    Terpolilli, Jason; Garau, Giovanni; Hill, Yvette; Tian, Rui; Howieson, John; Bräu, Lambert; Goodwin, Lynne; Han, James; Liolios, Konstantinos; Huntemann, Marcel; Pati, Amrita; Woyke, Tanja; Mavromatis, Konstantinos; Markowitz, Victor; Ivanova, Natalia; Kyrpides, Nikos; Reeve, Wayne

    2013-12-20

    Ensifer medicae WSM1369 is an aerobic, motile, Gram-negative, non-spore-forming rod that can exist as a soil saprophyte or as a legume microsymbiont of Medicago. WSM1369 was isolated in 1993 from a nodule recovered from the roots of Medicago sphaerocarpos growing at San Pietro di Rudas, near Aggius in Sardinia (Italy). WSM1369 is an effective microsymbiont of the annual forage legumes M. polymorpha and M. sphaerocarpos. Here we describe the features of E. medicae WSM1369, together with genome sequence information and its annotation. The 6,402,557 bp standard draft genome is arranged into 307 scaffolds of 307 contigs containing 6,656 protein-coding genes and 79 RNA-only encoding genes. This rhizobial genome is one of 100 sequenced as part of the DOE Joint Genome Institute 2010 Genomic Encyclopedia for Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB) project.

  16. Genome sequence of Ensifer medicae strain WSM1369; an effective microsymbiont of the annual legume Medicago sphaerocarpos

    PubMed Central

    Terpolilli, Jason; Garau, Giovanni; Hill, Yvette; Tian, Rui; Howieson, John; Bräu, Lambert; Goodwin, Lynne; Han, James; Liolios, Konstantinos; Huntemann, Marcel; Pati, Amrita; Woyke, Tanja; Mavromatis, Konstantinos; Markowitz, Victor; Ivanova, Natalia; Kyrpides, Nikos; Reeve, Wayne

    2013-01-01

    Ensifer medicae WSM1369 is an aerobic, motile, Gram-negative, non-spore-forming rod that can exist as a soil saprophyte or as a legume microsymbiont of Medicago. WSM1369 was isolated in 1993 from a nodule recovered from the roots of Medicago sphaerocarpos growing at San Pietro di Rudas, near Aggius in Sardinia (Italy). WSM1369 is an effective microsymbiont of the annual forage legumes M. polymorpha and M. sphaerocarpos. Here we describe the features of E. medicae WSM1369, together with genome sequence information and its annotation. The 6,402,557 bp standard draft genome is arranged into 307 scaffolds of 307 contigs containing 6,656 protein-coding genes and 79 RNA-only encoding genes. This rhizobial genome is one of 100 sequenced as part of the DOE Joint Genome Institute 2010 Genomic Encyclopedia for Bacteria and Archaea-Root Nodule Bacteria (GEBA-RNB) project. PMID:24976897

  17. Storm Peak Laboratory 5th-6th Grade Climate and Weather Program

    NASA Astrophysics Data System (ADS)

    McCubbin, I. B.; Hallar, A. G.

    2008-12-01

    science. At the end of the day each student has a data sheet with measurements recorded from 5 locations of different elevations to take back to the classroom. Following the field trip, SPL scientists and educators visit the school for a follow-up to help children grasp concepts, represent their data set collected in graphical formats, answer questions, and evaluate students" learning. Currently, approximately 250 students annually participate in the SPL 5th and 6th grade climate education program.

  18. A rapid whole genome sequencing and analysis system supporting genomic epidemiology (7th Annual SFAF Meeting, 2012)

    ScienceCinema

    FitzGerald, Michael [Broad Institute

    2016-07-12

    Michael FitzGerald on "A rapid whole genome sequencing and analysis system supporting genomic epidemiology" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  19. A rapid whole genome sequencing and analysis system supporting genomic epidemiology (7th Annual SFAF Meeting, 2012)

    SciTech Connect

    FitzGerald, Michael

    2012-06-01

    Michael FitzGerald on "A rapid whole genome sequencing and analysis system supporting genomic epidemiology" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  20. Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers.

    PubMed Central

    Reeve, Wayne; O’Hara, Graham; Chain, Patrick; Ardley, Julie; Bräu, Lambert; Nandesena, Kemanthi; Tiwari, Ravi; Copeland, Alex; Nolan, Matt; Han, Cliff; Brettin, Thomas; Land, Miriam; Ovchinikova, Galina; Ivanova, Natalia; Mavromatis, Konstantinos; Markowitz, Victor; Kyrpides, Nikos; Melino, Vanessa; Denton, Matthew; Yates, Ron; Howieson, John

    2010-01-01

    Rhizobium leguminosarum bv trifolii is a soil-inhabiting bacterium that has the capacity to be an effective nitrogen fixing microsymbiont of a diverse range of annual Trifolium (clover) species. Strain WSM1325 is an aerobic, motile, non-spore forming, Gram-negative rod isolated from root nodules collected in 1993 from the Greek Island of Serifos. WSM1325 is produced commercially in Australia as an inoculant for a broad range of annual clovers of Mediterranean origin due to its superior attributes of saprophytic competence, nitrogen fixation and acid-tolerance. Here we describe the basic features of this organism, together with the complete genome sequence, and annotation. This is the first completed genome sequence for a microsymbiont of annual clovers. We reveal that its genome size is 7,418,122 bp encoding 7,232 protein-coding genes and 61 RNA-only encoding genes. This multipartite genome contains 6 distinct replicons; a chromosome of size 4,767,043 bp and 5 plasmids of size 828,924 bp, 660,973 bp, 516,088 bp, 350,312 bp and 294,782 bp. PMID:21304718

  1. An Analysis of Writing Dispositions of 6th Grade Students in Terms of Different Variables

    ERIC Educational Resources Information Center

    Tabak, Gurkan; Topuzkanamis, Ersoy

    2014-01-01

    This research was conducted with an aim to analyze the writing dispositions of the 6th grade students in terms of different variables. The research was carried out based on the descriptive survey model. The participants of the research are composed of a total of 672 students as 342 male students and 330 female students from Ankara, Balikesir,…

  2. Parental Stress with Homeschooling K-6th Grade Children in a South Florida District

    ERIC Educational Resources Information Center

    Myers, Jennifer A.

    2017-01-01

    Parental Stress With Homeschooling K-6th Grade Children in a South Florida District. Jennifer A. Myers, 2015: Applied Dissertation, Nova Southeastern University, Abraham S. Fischler College of Education. ERIC Descriptors: Homeschooling, Stress, Stress Management, Coping This applied dissertation study was designed to inform and advance knowledge…

  3. The Roles of School Readiness and Poverty-Related Risk for 6th Grade Outcomes

    PubMed Central

    Pressler, Emily; Raver, C. Cybele; Friedman-Krauss, Allison H.; Roy, Amanda

    2016-01-01

    Low-income students are at increased risk for grade retention and suspension, which dampens their chances of high school graduation, college attendance, and future success. Drawing from a sample of 357 children and their families who participated in the Chicago School Readiness Project, we examine whether greater exposure to cumulative poverty-related risk from preschool through 5th grade is associated with greater risk of student retention and suspension in 6th grade. Logistic regression results indicate that exposure to higher levels of cumulative risk across the elementary school years is associated with students’ increased risk of retention in 6th grade, even after controlling for child school readiness skills and other covariates. Importantly, findings of the association between average cumulative risk exposure and student suspension are more complex; the role of poverty-related risk is reduced to non-significance once early indicators of child school readiness and other covariates are included in regression models. While, children’s early externalizing behavior prior to kindergarten places children at greater risk of suspension 7 years later, children’s higher levels of internalizing behaviors and early math skills are associated with significantly decreased risk of suspension in the 6th grade. Together, findings from the study suggest the complex ways that both early school readiness and subsequent exposure to poverty-related risk may both serve as compelling predictors of children’s likelihood of “staying on track” academically in the 6th grade. PMID:27867447

  4. Curriculum Reform Movements and Science Textbooks: A Retrospective Examination of 6th Grade Science Textbooks

    ERIC Educational Resources Information Center

    Alpaslan, Muhammet Mustafa; Yalvac, Bugrahan; Loving, Cathleen C.

    2015-01-01

    Over 50 years, two major reform efforts in science education took place. The purpose of the present study is to explore how the educational reforms were reflected in nine 6th grade science textbooks published in 1975, in 1985 and in 1997 in terms of (a) the materials used, (b) the contexts to which the electricity concept was related, (c) the type…

  5. 10. 'Southern Pacific Company, 6th Crossing of Sacramento River, One ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. 'Southern Pacific Company, 6th Crossing of Sacramento River, One 208'-10-1/2' C. to C. End Pins S. Tr. Thro. Skew Span, Scale 1' = 10', The Phoenix Bridge Co., Phoenixville, Pa., April 12, 1901, Drg. 45' - Southern Pacific Railroad Shasta Route, Bridge No. 301.85, Milepost 301.85, Pollard Flat, Shasta County, CA

  6. Sneak Preview of Berkeley Lab's Science at the Theatre on June 6th, 2011

    ScienceCinema

    Sanii, Babak

    2016-07-12

    Babak Sanii provides a sneak preview of Berkeley Lab's next Science at the Theater Event: Big Thinking: The Power of Nanoscience. Berkeley Lab scientists reveal how nanoscience will bring us cleaner energy, faster computers, and improved medicine. Berkeley Repertory Theatre on June 6th, 2011

  7. Sneak Preview of Berkeley Lab's Science at the Theatre on June 6th, 2011

    SciTech Connect

    Sanii, Babak

    2011-01-01

    Babak Sanii provides a sneak preview of Berkeley Lab's next Science at the Theater Event: Big Thinking: The Power of Nanoscience. Berkeley Lab scientists reveal how nanoscience will bring us cleaner energy, faster computers, and improved medicine. Berkeley Repertory Theatre on June 6th, 2011

  8. Summary of the National Technicians' Conference ASE/NSLC York--5/6th July 2012

    ERIC Educational Resources Information Center

    Bostock, Julia, Comp.

    2012-01-01

    This article presents a summary of the National Technicians' Conference ASE/NSLC York from July 5th to July 6th 2012. Approximately 160 technicians attended the Conference on both days. The programme included workshops and lectures and was repeated on the Friday, so that technicians who stayed for both days were able to take part in a variety of…

  9. Association Genetics of Populus trichocarpa or Resequencing in Populus: Towards Genome Wide Association Genetics (2011 JGI User Meeting)

    SciTech Connect

    Tuskan, Gerry

    2011-03-23

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Gerry Tuskan of Oak Ridge National Laboratory on "Resequencing in Populus: Towards Genome Wide Association Genetics" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  10. Association Genetics of Populus trichocarpa or Resequencing in Populus: Towards Genome Wide Association Genetics (2011 JGI User Meeting)

    ScienceCinema

    Tuskan, Gerry

    2016-07-12

    The U.S. Department of Energy Joint Genome Institute (JGI) invited scientists interested in the application of genomics to bioenergy and environmental issues, as well as all current and prospective users and collaborators, to attend the annual DOE JGI Genomics of Energy & Environment Meeting held March 22-24, 2011 in Walnut Creek, Calif. The emphasis of this meeting was on the genomics of renewable energy strategies, carbon cycling, environmental gene discovery, and engineering of fuel-producing organisms. The meeting features presentations by leading scientists advancing these topics. Gerry Tuskan of Oak Ridge National Laboratory on "Resequencing in Populus: Towards Genome Wide Association Genetics" at the 6th annual Genomics of Energy & Environment Meeting on March 23, 2011

  11. Evolutionary Perspectives on Diversity of Lignocellulose Decay Mechanisms in Basidionycetes (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Hibbett, David [Clark University

    2016-07-12

    David Hibbett from Clark University on "Evolutionary Perspectives on Diversity of Lignocellulose Decay Mechanisms in Basidiomycetes" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  12. Genetic Regulation of Grass Biomass Accumulation and Biological Conversion Quality (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Hazen, Sam

    2013-03-01

    Sam Hazen of the University of Massachusetts on "Genetic Regulation of Grass Biomass Accumulation and Biological Conversion Quality" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  13. Metabolic Engineering of Clostridium thermocellum for Biofuel Production (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Guess, Adam

    2013-03-01

    Adam Guss of Oak Ridge National Lab on "Metabolic engineering of Clostridium thermocellum for biofuel production" at the 8th Annual Genomics of Energy & Environment Meeting on March 28, 2013 in Walnut Creek, Calif.

  14. Succession of Phylogeny and Function During Plant Litter Decomposition (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Brodie, Eoin

    2013-03-01

    Eoin Brodie of Berkeley Lab on "Succession of phylogeny and function during plant litter decomposition" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  15. Assembly-driven metagenomics of a hypersaline microbial ecosystem (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Allen, Eric

    2013-03-01

    Eric Allen of Scripps and UC San Diego on "Assembly-driven metagenomics of a hypersaline microbial ecosystem" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  16. Delineating Molecular Interaction Mechanisms in an In Vitro Microbial-Plant Community (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Larsen, Peter

    2013-03-01

    Peter Larsen of Argonne National Lab on "Delineating molecular interaction mechanisms in an in vitro microbial-plant community" at the 8th Annual Genomics of Energy & Environment Meeting in Walnut Creek, Calif.

  17. Evolutionary Perspectives on Diversity of Lignocellulose Decay Mechanisms in Basidionycetes (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Hibbett, David

    2012-03-21

    David Hibbett from Clark University on "Evolutionary Perspectives on Diversity of Lignocellulose Decay Mechanisms in Basidiomycetes" at the 7th Annual Genomics of Energy & Environment Meeting on March 21, 2012 in Walnut Creek, California.

  18. Natural variation in Brachypodium disctachyon: Deep Sequencing of Highly Diverse Natural Accessions (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Gordon, Sean

    2013-03-01

    Sean Gordon of the USDA on "Natural variation in Brachypodium disctachyon: Deep Sequencing of Highly Diverse Natural Accessions" at the 8th Annual Genomics of Energy & Environment Meeting on March 27, 2013 in Walnut Creek, Calif.

  19. Modulation of Root Microbiome Community Assembly by the Plant Immune Response (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Lebeis, Sarah

    2013-03-01

    Sarah Lebeis of University of North Carolina on "Modulation of root microbiome community assembly by the plant immune response" at the 8th Annual Genomics of Energy & Environment Meeting on March 28, 2013 in Walnut Creek, Calif.

  20. Biodiversity Monitoring Using NGS Approaches on Unusual Substrates (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Gilbert, Tom

    2013-03-01

    Tom Gilbert of the Natural History Museum of Denmark on "Biodiversity monitoring using NGS approaches on unusual substrates" at the 8th Annual Genomics of Energy & Environment Meeting in Walnut Creek, Calif.

  1. TARA OCEANS: A Global Analysis of Oceanic Plankton Ecosystems (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect

    Karsenti, Eric

    2013-03-01

    Eric Karsenti of EMBL delivers the closing keynote on "TARA OCEANS: A Global Analysis of Oceanic Plankton Ecosystems" at the 8th Annual Genomics of Energy & Environment Meeting on March 28, 2013 in Walnut Creek, Calif.

  2. Prevalence of Elevated Blood Pressure in Hispanic versus Non-Hispanic 6th Graders

    ERIC Educational Resources Information Center

    Tarlton, Patricia A.

    2007-01-01

    Blood pressure screening was conducted on 4,311 (Hispanic n = 763 [17.7%], White n = 2,566 [59.5%], African American n = 610 [14.1%], Asian n = 136 [3.2%], Multiracial n = 231 [5.4%], and Native American n = 5 [0.1%]) 6th-grade students enrolled in Seminole County, Florida, Public Schools from August to December 2005. Prevalence of obesity was 21%…

  3. Multiwavelength observations of XTE J1859+226 on 1999, November 6th

    NASA Astrophysics Data System (ADS)

    Haswell, C. A.; Chaty, S.; Norton, A. J.; Chen, W.; Hynes, R. I.

    1999-11-01

    Further simultaneous HST and RXTE observations (visit #3) of the new X-ray transient XTE J1859+226 are scheduled for November 6th 1999 19:37 - 22:22 UT. Coordinated multi-wavelength observations (simultaneous, near-simultaneous, and following the evolution over days/weeks) would be extremely helpful. If you can observe simultaneously with HST and/or RXTE, high time-resolution data (< 10 seconds) will be particularly useful.

  4. Recurrent 6th nerve palsy in a child following different live attenuated vaccines: case report

    PubMed Central

    2012-01-01

    Background Recurrent benign 6th nerve palsy in the paediatric age group is uncommon, but has been described following viral and bacterial infections. It has also been temporally associated with immunization, but has not been previously described following two different live attenuated vaccines. Case presentation A case is presented of a 12 month old Caucasian boy with recurrent benign 6th nerve palsy following measles-mumps-rubella and varicella vaccines, given on separate occasions with complete recovery following each episode. No alternate underlying etiology was identified despite extensive investigations and review. Conclusions The majority of benign 6th nerve palsies do not have a sinister cause and have an excellent prognosis, with recovery expected in most cases. The exact pathophysiology is unknown, although hypotheses including autoimmune mechanisms and direct viral invasion could explain the pathophysiology behind immunization related nerve palsies. It is important to rule out other aetiologies with thorough history, physical examination and investigations. There is limited information in the literature regarding the safety of a repeat dose of a live vaccine in this setting. Future immunizations should be considered on a case-by-case basis. PMID:22545865

  5. A Regiment Like No Other: The 6th Marine Regiment at Belleau Wood

    DTIC Science & Technology

    2012-06-08

    academic crucible type of setting. They had been through the pressure of academia and, for some, the stress of post-graduation jobs. With athletes, he was...ready for war.76 Col Catlin described the drill sergeant best when he said, “Much of the recruit’s progress is due to the labours of the drill Sergeant...between these two regiments, “[the 6th Regiment’s] early training was somewhat more difficult, but it soon found itself, and when the stress of battle

  6. Improving 6th Grade Climate Literacy using New Media (CLINM) and Teacher Professional Development

    NASA Astrophysics Data System (ADS)

    Smith, G.; Schmidt, C.; Metzger, E. P.; Cordero, E. C.

    2012-12-01

    The NASA-funded project, Improving 6th Grade Climate Literacy using New Media (CLINM), is designed to improve the climate literacy of California's 450,000 6th-grade students through teacher professional development that presents climate change as an engaging context for teaching earth science standards. The project fosters experience-based interaction among learners and encourages expressive creativity and idea-exchange via the web and social media. The heart of the CLINM project is the development of an online educator-friendly experience that provides content expert-reviewed, teacher-tested, standards-based educational resources, classroom activities and lessons that make meaningful connections to NASA data and images as well as new media tools (videos, web, and phone applications) based on the Green Ninja, a climate-action superhero who fights global warming by inspiring personal action (www.greenninja.info). In this session, we will discuss this approach to professional development and share a collection of teacher-tested CLINM resources. CLINM resources are grounded in earth system science; classroom activities and lessons engage students in exploration of connections between natural systems and human systems with a particular focus on how climate change relates to everyone's need for food, water, and energy. CLINM uses a team-based approach to resource development, and partners faculty in San José State University's (SJSU) colleges of Science, Education, and Humanities and the Arts with 6th-grade teachers from local school districts, a scientist from NASA Ames Research Center and climate change education projects at Stanford University, the University of Nebraska at Lincoln, and the University of Idaho. Climate scientists and other content experts identify relevant concepts and work with science educators to develop and/or refine classroom activities to elucidate those concepts; activities are piloted in pre-service science methods courses at SJSU and in

  7. Bone Lose of the Ancient Mediterranean lumbar vertebrae : Iasos, 6th century ad.

    NASA Astrophysics Data System (ADS)

    Kaya, Serdar; Solmaz, Ilker; Ilıca, A. Turan; Karaçalıoğlu, Özgür; Damla Yılmaz, Nalan; Başoğlu, Okşan; Kılıc, Selim; Izci, Yusuf

    Evaluation of bone mineral density (BMD) of the ancient peoples has received great interest by anthropologists. The aims of this study are to investigate the lumbar vertebrae of the Iasos people during the Byzantine period, in order to determine the prevalence of bone loss and to interpret dietary conditions of ancient Mediterranean populations. Lumbar vertebrae belonging to twenty eight skeletons of the 6th c AD were analyzed by radiographs and dual energy X-ray absorptiometry. The BMD values for each biologic sex and age group were compared. The correlation between the BMD and radiological features was also analyzed. The mean BMD was 0.940 g/cm2. BMD was decreased by aging in both sexes, but it was not significant. Osteopenia was found in 11 (39%) and osteoporosis in 4 (14.3%) out 28 vertebrae. The BMD was normal in 13 (46%) out of 28 vertebrae. Osteopenia was present in 7 (38%) of 18 male vertebrae and 4 (40%) of 10 female vertebrae. The spine score was high in the male group and there was a strong positive correlation between the BMD and spine score for both sexes. This study revealed that the BMD decreased by aging and that osteopenia was a problem in both sexes of the Iasos people during the 6th c AD. There was no correlation between the BMD and radiological features for age groups and biological sexes.

  8. BARC 2010 Annual Report for NRSP-8 National Animal Genome Research Program (NAGRP)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    BARC 2010 has contributed to the National Animal Genome Research Program (NAGRP). The NRSP8 NAGRP’s objectives are 1) Enhance and integrate genetic and physical maps of agriculturally important animals for cross species comparisons and sequence annotation; 2) Facilitate integration of genomic, trans...

  9. BARC 2009 Annual Report for NRSP-8 National Animal Genome Research Program (NAGRP)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    BARC 2009 has contributed to the National Animal Genome Research Program (NAGRP). The NRSP8 NAGRP’s objectives are 1) Enhance and integrate genetic and physical maps of agriculturally important animals for cross species comparisons and sequence annotation; 2) Facilitate integration of genomic, trans...

  10. Towards the Perfect Genome Sequence (Opening Keynote) ( 7th Annual SFAF Meeting, 2012)

    ScienceCinema

    Weinstock, George [Washington University

    2016-07-12

    George Weinstock, associate director at the Genome Institute at Washington University, delivered the opening keynote "Towards the Perfect Genome Sequence" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  11. Towards the Perfect Genome Sequence (Opening Keynote) ( 7th Annual SFAF Meeting, 2012)

    SciTech Connect

    Weinstock, George

    2012-06-01

    George Weinstock, associate director at the Genome Institute at Washington University, delivered the opening keynote "Towards the Perfect Genome Sequence" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  12. 28th Annual JPMorgan Healthcare Conference--Human Genome Sciences and Celgene.

    PubMed

    Gale, Sophie; Croasdell, Gary

    2010-03-01

    The JPMorgan Healthcare Conference, held in San Francisco, included presentations by various pharmaceutical companies summarizing their achievements in 2009 and expectations for 2010. This conference report highlights presentations from Human Genome Sciences Inc and Celgene Corp. Investigational drugs from Human Genome Sciences, including belimumab (in collaboration with GlaxoSmithKline plc), albinterferon alfa-2b (with Novartis AG), mapatumumab (with Takeda Pharmaceutical Co Ltd) and HGS-1029, and from Celgene, including romidepsin, pomalidomide, apremilast and PDA-001 (Celgene Cellular Therapeutics), are discussed.

  13. Burst speciation processes and genomic expansion in the neotropical annual killifish genus Austrolebias (Cyprinodontiformes, Rivulidae).

    PubMed

    García, G; Gutiérrez, V; Ríos, N; Turner, B; Santiñaque, F; López-Carro, B; Folle, G

    2014-02-01

    The extent to which genome sizes and other nucleotypic factors influence the phyletic diversification of lineages has long been discussed but remains largely unresolved. In the present work, we present evidence that the genomes of at least 16 species of the neotropical rivulid killifish genus Austrolebias are unusually large, with an average DNA content of about 5.95 ± 0.45 picograms per diploid cell (mean C-value of about 2.98 pg). They are thus larger than the genomes of very nearly all other diploid, i.e. non-(paleo) polyploid species of actinopterygian fishes so far reported. Austrolebias species appear to be conventional diploids in all other respects and there is no reason to believe that they arise from polyploid ancestors. The genome sizes reported for other rivulid killifishes, including a putative sister group, are considerably smaller and fall within the range typical of most other cyprinodontoid species. Therefore, it appears that the ancestor(s) of contemporary Austrolebias have undergone one or more episodes of genome expansion encompassing sudden speciation process during the Pleistocene. In addition, these findings are consistent with the hypothesis of a positive correlation between species richness and genome size.

  14. An integrated exploration model for Council Run field analogs: Regional geology and seismic stratigraphy of Devonian 6th Elk sandstones

    SciTech Connect

    Kelleher, G.; Johnson, R. )

    1991-08-01

    A geologic study of the Devonian Lock Haven 6th Elk formation along the structural front of Pennsylvania and Maryland suggest that present-day structures were active at the time of deposition. These structures barred deposition to the west and helped to localize sands in a northeast-southwest fairway. The 6th Elk sandstones occur in two major depositional lobes (located in Centre and Somerset counties in Pennsylvania, and Garret County, Maryland) and were deposited on a shallow-marine shelf by turbidity currents and later modified by storm-generated currents. Deposition of 6th Elk sands may also have been influenced by cross-strike discontinuities. A seismic study of the Council Run field aids in subsurface identification of the 6th Elk. A high-amplitude seismic anomaly across the Council Run field is correlated with increasing san thickness. Two dimensional modeling suggests that the seismic response is extremely sensitive to specific acquisition and processing techniques including filter and phase variability. Additional attribute analysis integrates the seismic data with the forward models. This results in a predictive method for potentially identifying 6th Elk sandstone development from seismic data. Applying the results of the seismic modeling at Council Run field to a seismic grid across the previously defined 6th Elk depositional fairway has identified many exploratory prospects in Lycoming and Bradford counties, Pennsylvania. This area coincides with the site of a third, previously documented, Upper Devonian depositional lobe.

  15. Uranium groundwater anomalies and L'Aquila earthquake, 6th April 2009 (Italy).

    PubMed

    Plastino, Wolfango; Povinec, Pavel P; De Luca, Gaetano; Doglioni, Carlo; Nisi, Stefano; Ioannucci, Luca; Balata, Marco; Laubenstein, Matthias; Bella, Francesco; Coccia, Eugenio

    2010-01-01

    Monitoring of chemical and physical groundwater parameters has been carried out worldwide in seismogenic areas with the aim to test possible correlations between their spatial and temporal variations and strain processes. Uranium (U) groundwater anomalies were observed during the preparation phases of the recent L'Aquila earthquake of 6th April 2009 in the cataclastic rocks near the overthrust fault crossing the deep underground Gran Sasso National Laboratory. The results suggest that U may be used as a potential strain indicator of geodynamic processes occurring before the seismic swarm and the main earthquake shock. Moreover, this justifies the different radon patterns before and after the main shock: the radon releases during and after the earthquake are much than more during the preparatory period because the process does not include only the microfracturing induced by stress-strain activation, but also radon increases accompanying groundwater U anomalies.

  16. Statistical Analysis of CFD Solutions from the 6th AIAA CFD Drag Prediction Workshop

    NASA Technical Reports Server (NTRS)

    Derlaga, Joseph M.; Morrison, Joseph H.

    2017-01-01

    A graphical framework is used for statistical analysis of the results from an extensive N- version test of a collection of Reynolds-averaged Navier-Stokes computational uid dynam- ics codes. The solutions were obtained by code developers and users from North America, Europe, Asia, and South America using both common and custom grid sequencees as well as multiple turbulence models for the June 2016 6th AIAA CFD Drag Prediction Workshop sponsored by the AIAA Applied Aerodynamics Technical Committee. The aerodynamic con guration for this workshop was the Common Research Model subsonic transport wing- body previously used for both the 4th and 5th Drag Prediction Workshops. This work continues the statistical analysis begun in the earlier workshops and compares the results from the grid convergence study of the most recent workshop with previous workshops.

  17. Rapid landscape change in 6th century northern Jordan: interdisciplinary geoarchaeological perspectives

    NASA Astrophysics Data System (ADS)

    Lucke, Bernhard

    2016-04-01

    Landscapes of the ancient fertile crescent are considered affected by soil degradation as result of long-term farming since the Neolithic, and impressive ruins of antiquity led to assumptions that their abandonment must have been conntected with reduced agricultural productivity. In this context, a valley fill near the site of Abila of the Decapolis in northern Jordan was apparently deposited largely during the 6th century AD, and provides evidence for a rapid and intense landscape change during the Late Byzantine period. However, an interdisciplinary case study of land use, soil development, and sediments found that the valley fill cannot be connected with large-scale soil erosion in the vicinity of the site. On the one hand, this is indicated by the distribution of soil development and archaeological material as marker of past land use activity in the past, which suggests that the best soils were and still are used intensively. On the other hand, the sediments seem to point to the occurrence of climatic extremes such as heavy floods, the occurrence of soil creep after water saturation, but also a significant shift to aridity which may have triggered socio-economic changes of subsistence strategies from agriculture to pastoralism. The dates of sediments which are available so far indicate that the climatic change seemingly occurred rapidly within approximately 100 years during the late 6th and early 7th century AD, possibly connected with the "year without sun" or 'Mystery Veil' which the Byzantine historian Procopius described in the year 536 AD. Modern analogies of the Pinatubo eruption in 1991 let it seem possible that a volcanic event, perhaps the outbreak of the Ilopango volcano, was connected with these environmental turbulences. Such events cannot be understood by isolated studies: without a broad interdisciplinary framework, single archives are prone to misinterpretation, and our understanding of the environmental history of Abila is still very limited.

  18. 6th Institute for Systems Biology International Symposium: Systems Biology and the Environment

    SciTech Connect

    Galitski, Timothy P.

    2007-04-23

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology is an annual two-day event gathering the most influential researchers transforming biology into an integrative discipline investigating complex systems. In recognition of the fundamental similarity between the scientific problems addressed in environmental science and systems biology studies at the molecular, cellular, and organismal levels, the 2007 Symposium featured global leaders in “Systems Biology and the Environment.” The objective of the 2007 “Systems Biology and the Environment” International Symposium was to stimulate interdisciplinary thinking and research that spans systems biology and environmental science. This Symposium was well aligned with the DOE’s Genomics: GTL program efforts to achieve scientific objectives for each of the three DOE missions: Develop biofuels as a major secure energy source for this century; Develop biological solutions for intractable environmental problems; Understand biosystems’ climate impacts and assess sequestration strategies. Our scientific program highlighted world-class research exemplifying these priorities. The Symposium featured 45 minute lectures from 12 researchers including: Penny/Sallie Chisholm of MIT gave the keynote address “Tiny Cells, Global Impact: What Prochlorococcus Can Teach Us About Systems Biology”, plus Jim Fredrickson of PNNL, Nitin Baliga of ISB, Steve Briggs of UCSD, David Cox of Perlegen Sciences, Antoine Danchin of Institut Pasteur, John Delaney of the U of Washington, John Groopman of Johns Hopkins, Ben Kerr of the U of Washington, Steve Koonin of BP, Elliott Meyerowitz of Caltech, and Ed Rubin of LBNL. The 2007 Symposium promoted DOE’s three mission areas among scientists from multiple disciplines representing academia, non-profit research institutions, and the private sector. As in all previous Symposia, we had

  19. Life Sciences Division and Center for Human Genome Studies Annual report 1989

    SciTech Connect

    Spitzmiller, D.; Bradbury, M.; Cram, L.S.

    1990-05-01

    This report summarizes the research and development activities of Los Alamos National Laboratory's Life Sciences Division and biological aspects of the Center for Human Genome Studies for the calendar year 1989. Future editions will include all human genome research projects. The technical portion of the report is divided into two parts: selected research highlights, and project descriptions and accomplishments. Research highlights provide a more detailed description of a select set of projects. A technical description of all projects is presented in sufficient detail to permit the informed reader to assess their scope and significance. 2 figs.

  20. U.S. Department of Energy (DOE)--Surface Biogeochemical Research (SBR) 6th Annual PI Meeting: Abstracts

    SciTech Connect

    Hazen Ed., T.C.

    2011-04-11

    On behalf of the Subsurface Biogeochemical Research (SBR) program managers in the Climate and Environmental Sciences Division (CESD), Office of Biological and Environmental Research (BER), welcome to the 2011 SBR Principal Investigators meeting. Thank you in advance for your attendance and your presentations at this year's meeting. As the events in Japan continue to unfold, we are all reminded that the research we perform on radionuclide behavior in the environment has implications beyond legacy waste cleanup and in fact has its place in the discussion on the expanded use of nuclear power. As in the past, there are three broad objectives to the Principal Investigators meeting: (1) to provide opportunities to share research results and promote interactions among the SBR scientists and other invited guests; (2) to evaluate the progress of each project within the program; and (3) to showcase the scientific expertise and research progress over the past year to senior managers within the DOE Office of Science, the technology offices within DOE, and other invited attendees from other Federal Agencies. This past year has seen a few significant changes within BER and within the SBR program. In November, our Associate Director for BER, Anna Palmisano, retired from Federal service. Just this month, Dr. Sharlene Weatherwax (Division Director for Biological Systems Sciences) has been named as the new Associate Director for BER. In August, BER welcomed Dr. Gary Geernaert as the new Division Director for CESD. Gary joins the division from Los Alamos National Laboratory with a background in atmospheric science. Within the SBR program, a new Strategic Plan was completed last June (currently posted on the SBR and the Office of Science website). The new strategic plan is intended to foster integration within the Environmental Systems Science portion of the BER budget that includes both SBR and Terrestrial Ecosystem Sciences (TES). Both these programs share a goal of advancing a predictive understanding of environmental processes and utilizing iterative, multidisciplinary approaches to understand complex environmental systems of relevance to DOE. CESD in general is undergoing continued discussions on integration among its programs in an effort to develop a new strategic plan for the division. This effort also includes identifying opportunities for integration with BER's Biological Systems Science Division (BSSD). The program this year includes three poster presentation sessions, six plenary sessions, and three breakout sessions. The plenary session on Tuesday morning will feature introductory presentations by BER program staff and three keynote addresses from Dr. Ken Bencala (USGS), Dr. Michael (Mick) Follows (MIT) and Dr. Sue Brantley (PSU) that will lead into three breakout sessions Tuesday afternoon. The breakout sessions are intended to highlight key developments in SBR research and foster a dialog among session participants on scientific paths forward in each particular area. The SBR program managers are asking for input from the SBR community at these sessions to help guide future efforts and/or identify areas of integration within BER programs. On Wednesday, plenary sessions will continue in the morning, followed by an early afternoon poster session. After an extended break for lunch, plenary sessions will continue in the afternoon, followed by an evening poster session. Thursday's plenary session will focus on selected highlights of research efforts at the IFRC sites and on a new potential TES field effort in the Arctic. This new field site is an obvious point of integration between the SBR and TES programs.

  1. Proceedings of the 6th Annual Advance Technology Workshop. ATW’ 98. 19-20th of May, 1998

    DTIC Science & Technology

    1998-05-01

    content to the attainment of a predetermined depth of understanding of design, we adapted the cognitive knowledge levels of Bloom’s Taxonomy (from six...Principles of neurodynamics , Academic Press,- New York. . SZILAS N. (1995), "Apprentissage dans les reseaux recurrents pour la modelisation

  2. Annual Review of Progress in Applied Computational Electromagnetics (6th), Held in Monterey, California on March 19-22, 1990

    DTIC Science & Technology

    1990-01-01

    387 SESSION lob: MODEUNG EM INTERACTION WITH BIOLOGICAL MEDIA ...problems. It is a tool for computing time harmonic fields in linear, homogeneous and isotropic media . Via Fourier transform also scattering of non-sinusoidal...overdetermined systems of equations. The strength of the MMP-3D code lies in nearfield calculations and in computations involving dielectric or lossy media . The

  3. ASTPHLD Annual Conference on Human Retrovirus Testing (6th) Held in Kansas City, Missouri on March 5 - 7, 1991

    DTIC Science & Technology

    1992-01-31

    Patricia E. Garrett, Ph.D. Scientist Director, Reg. Affairs & Special Projects WHO, Global Programme on AIDS Boston Biomedica , Inc. CH-1211 375 West Street...Kansas City, MO 64113 Redmond, WA 98052 Steven Rais Percy S. Pan Vice President, Marketing & Sales Marketing Services Manager Boston Biomedica , Inc...Regional Product Manager Abbott Laboratories Richard T. Schumacher 5605 N. MacArthur, Suite 700 President Irving, TX 75038 Boston Biomedica , Inc. (214) 518

  4. Annual Trauma Anesthesia and Critical Care Symposium (6th) Held in Baltimore, MD on 20-23 May 1993

    DTIC Science & Technology

    1993-10-01

    FRCAnaes 12:15 P.M. Intravenous Agents LevnM. Capn, MI) 12:45 P.M. Inhalation Agents LewoM. Coaxn, MD 1:15 P.M. Discussion 1:30 P.M. Lunch (on your own...Pathophysiologic Responses to Pain After Injury Leo H. D. J. Boo#, MD, PhD, FRCAnaes 3:30 P.M. Systemically Administered Agents T. James Gallagher, MD...Organization of Trauma Care A. Trauma Systems 1. The Orange County Experience 2. National Plans a. Trauma Care Systems Planning and Development Act b

  5. Proceedings of the Annual Conference on Academic Computing Applications (6th, Indiana University Northwest, Bloomington, Indiana, April 6, 1979).

    ERIC Educational Resources Information Center

    Stentz, Michael, Ed.; Motsinger, Linda, Ed.

    Topics which range from the more popular computing applications in accounting, statistics, and administration to the less ordinary applications of the computer to the fields of fine arts, medicine, and linguistics, are discussed in this collection of 22 conference papers. The papers are divided into four tracks: the first deals with statistical…

  6. Annual Symposium on Subtypes of Muscarinic Receptors (6th) Held in Ft. Lauderdale, Florida on November 9 -12, 1994.

    DTIC Science & Technology

    1995-03-03

    Alzheimer’s disease was also presented. Funds granted by USAMRAA made it possible to publish quickly and disseminate widely the Symposium Proceedings. The edited manuscripts of the invited papers and the abstracts of poster papers were published Feb.10, 1995 as Vol.56, Nos.11/12 of Life Sciences and sent free to its thousands of subscribers and to hundreds of others. Grants from NSF and NIH supported the attendance of 29 pre- and postdoctoral fellows, 26 of whom presented posters. The choice of dates and venue for the Symposium also made it possible for many to

  7. FOREWORD: 6th International Conference on Pumps and Fans with Compressors and Wind Turbines (ICPF2013)

    NASA Astrophysics Data System (ADS)

    Wu, Yulin; Wang, Zhengwei; Yuan, Shouqi; Shi, Weidong; Liu, Shuhong; Luo, Xingqi; Wang, Fujun

    2013-12-01

    The 6th International Conference on Pumps and Fans with Compressors and Wind Turbines (ICPF 2013) was held in Beijing, China, 19-22 September 2013, which was jointly organized by Tsinghua University and Jiangsu University. The co-organizers were Zhejiang University, Zhejiang Sci-Tech University, The State Key Laboratory of Hydroscience and Engineering, The State Key Laboratory of Automotive Safety and Energy and Beijing International Science and Technology Cooperation Base for CO2 Utilization and Reduction. The sponsor of the conference was Concepts NREC. The First International Conference on Pumps and Systems (May 1992), the Second International Conference on Pumps and Fans (October 1995), the Third International Conference on Pumps and Fans (October 1998), and the Fourth International Conference on Pumps and Fans (26-29 August 2002) were all held in Beijing and were organized by the late famous Chinese professor on fluid machinery and engineering, Professor Zuyan Mei of Tsinghua University. The conference was interrupted by the death of Professor Mei in 2003. In order to commemorate Professor Mei, the organizing committee of ICPF decided to continue organizing the conference series. The Fifth Conference on Pumps and Systems (2010 ICPF) took place in Hangzhou, Zhejiang Province, China, 18-21 October 2010, and it was jointly organized by Zhejiang University and Tsinghua University. With the development of renewable energy and new energy in China and in the world, some small types of compressor and some types of pump, as well as wind turbines are developing very fast; therefore the ICPF2013 conference included compressors and wind turbines. The theme of the conference was the application of renewable energy of pumps, compressors, fans and blowers. The content of the conference was the basic study, design and experimental study of compressors, fans, blowers and pumps; the CFD application on pumps and fans, their transient behavior, unsteady flows and multi-phase flow

  8. 1/6TH SCALE STRIP EFFLUENT FEED TANK-MIXING RESULTS USING MCU SOLVENT

    SciTech Connect

    Hansen, E

    2006-02-01

    The purpose of this task was to determine if mixing was an issue for the entrainment and dispersion of the Modular Caustic Side Solvent Extraction (CSSX) Unit (MCU) solvent in the Defense Waste Processing Facility (DWPF) Strip Effluent Feed Tank (SEFT). The MCU strip effluent stream containing the Cs removed during salt processing will be transferred to the DWPF for immobilization in HLW glass. In lab-scale DWPF chemical process cell testing, mixing of the solvent in the dilute nitric acid solution proved problematic, and the Savannah River National Laboratory (SRNL) was requested to perform scaled SEFT mixing tests to evaluate whether the problem was symptomatic of the lab-scale set-up or of the solvent. The solvent levels tested were 228 and 235 ppm, which represented levels near the estimated DWPF solvent limit of 239 ppm in 0.001M HNO{sub 3} solution. The 239 ppm limit was calculated by Norato in X-CLC-S-00141. The general approach for the mixing investigation was to: (1) Investigate the use of fluorescent dyes to aid in observing the mixing behavior. Evaluate and compare the physical properties of the fluorescent dyed MCU solvents to the baseline Oak Ridge CSSX solvent. Based on the data, use the dyed MCU solvent that best approximates the physical properties. (2) Use approximately a 1/6th linear scale of the SEFT to replicate the internal configuration for DWPF mixing. (3) Determine agitator speed(s) for scaled testing based on the DWPF SEFT mixing speed. (4) Perform mixing tests using the 1/6th SEFT and determine any mixing issues (entrainment/dispersion, accumulation, adhesion) through visual observations and by pulling samples to assess uniformity. The mixing tests used MCU solvent fabricated at SRNL blended with Risk Reactor DFSB-K43 fluorescent dye. This dyed SRNL MCU solvent had equivalent physical properties important to mixing as compared to the Oak Ridge baseline solvent, blended easily with the MCU solvent, and provided an excellent visual aid.

  9. Latina girls' identities-in-practice in 6th grade science

    NASA Astrophysics Data System (ADS)

    Tan, Edna

    Inequalities and achievement gaps in science education among students from different racial and socioeconomic backgrounds as well as between genders in the United States are due to not just access to resources, but also to the incongruence between identities of school science with identities salient to minority students. Minority girls are especially portrayed to be estranged from prototypical school science Discourse, often characterized as white, middle class, and masculine. This dissertation, based on a two-year ethnographic study in an urban middle school in New York City, describes the authoring of novel identities-in-practice of minority girls in a 6th grade science classroom. The findings indicate that minority girls draw from out-of-school identities salient to them to author novel identities-in-practice in the various figured worlds of the 6th grade science classroom. Through taking such authorial stances, minority girls exhibit agency in negotiating for wider boundaries in their school science participation and broker for hybrid spaces of school science where the school science Discourse was destabilized and challenged to be more inclusive of everyday funds of knowledge and Discourses important to the students. The findings also highlight the dialectic relationship between an individual students' learning and participation and the school science community-of-practice and the implications such a relationship has on the learning of both individual students and the collective community-of-practice. From year one findings, curricular adaptations were enacted, with teacher and student input, on lessons centering on food and nutrition. The adapted curriculum specifically solicited for nontraditional funds of knowledge and Discourse from students and were grounded strongly in relevance to students' out of school lives. The hybrid spaces collectively brokered for by the community-of-practice were transformed in three ways: physically, politically, and

  10. PREFACE: 6th International Workshop on Multi-Rate Processes and Hysteresis (MURPHYS2012)

    NASA Astrophysics Data System (ADS)

    Dimian, Mihai; Rachinskii, Dmitrii

    2015-02-01

    The International Workshop on Multi-Rate Processes and Hysteresis (MURPHYS) conference series focuses on multiple scale systems, singular perturbation problems, phase transitions and hysteresis phenomena occurring in physical, biological, chemical, economical, engineering and information systems. The 6th edition was hosted by Stefan cel Mare University in the city of Suceava located in the beautiful multicultural land of Bukovina, Romania, from May 21 to 24, 2012. This continued the series of biennial multidisciplinary conferences organized in Cork, Ireland from 2002 to 2008 and in Pécs, Hungary in 2010. The MURPHYS 2012 Workshop brought together more than 50 researchers in hysteresis and multi-scale phenomena from the United State of America, the United Kingdom, France, Germany, Italy, Ireland, Czech Republic, Hungary, Greece, Ukraine, and Romania. Participants shared and discussed new developments of analytical techniques and numerical methods along with a variety of their applications in various areas, including material sciences, electrical and electronics engineering, mechanical engineering and civil structures, biological and eco-systems, economics and finance. The Workshop was sponsored by the European Social Fund through Sectoral Operational Program Human Resources 2007-2013 (PRO-DOCT) and Stefan cel Mare University, Suceava. The Organizing Committee was co-chaired by Mihai Dimian from Stefan cel Mare University, Suceava (Romania), Amalia Ivanyi from the University of Pecs (Hungary), and Dmitrii Rachinskii from the University College Cork (Ireland). All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the Editors. Reviews were conducted by expert referees to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The Guest Editors wish to place on record their sincere gratitude to Miss Sarah Toms for the assistance she provided

  11. Systems Biology Approaches to Dissecting Plant Cell Wall Biosynthesis Genes in Poplus (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Glass, N Louise [UC Berkeley

    2016-07-12

    N. Louise Glass from the University of California, Berkeley, presents a talk titled "Systems Biology Approaches to Dissecting Plant Cell Wall Biosynthesis Genes in Poplus" at the JGI 7th Annual Users Meeting: Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, California.

  12. In Situ Expression of Acidic and Thermophilic Carbohydrate Active Enzymes by Filamentous Fungi (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    SciTech Connect

    Mosier, Annika

    2012-03-22

    Annika Mosier, graduate student from Stanford University presents a talk titled "In Situ Expression of Acidic and Thermophilic Carbohydrate Active Enzymes by Filamentous Fungi" at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

  13. In Situ Expression of Acidic and Thermophilic Carbohydrate Active Enzymes by Filamentous Fungi (JGI Seventh Annual User Meeting 2012: Genomics of Energy and Environment)

    ScienceCinema

    Mosier, Annika [Stanford University

    2016-07-12

    Annika Mosier, graduate student from Stanford University presents a talk titled "In Situ Expression of Acidic and Thermophilic Carbohydrate Active Enzymes by Filamentous Fungi" at the JGI User 7th Annual Genomics of Energy & Environment Meeting on March 22, 2012 in Walnut Creek, Calif

  14. Leather material found on a 6th B.C. Chinese bronze sword: a technical study.

    PubMed

    Luo, Wugan; Si, Yi; Wang, Hongmin; Qin, Ying; Huang, Fengchun; Wang, Changsui

    2011-09-01

    During July to November, 2006, an important archaeological excavation was conducted in Yun country, Hubei province, southern China. Chinese archaeologists found some remnant of leather materials, covered with red pigments, on a 6th century B.C. Chinese bronze sword. To understand the technology/ies that may have been utilized for manufacturing the leathers, a combined of Raman spectroscopy, FT-IR and XRF was thus applied to the remnant of leather materials. Raman analyses showed that red pigment on the leather was cinnabar (HgS). FT-IR and XRF analyses indicated that the content of some elements, such as Ca (existing as CaCO3) and Fe (existing as Fe2O3), were much higher than those in the surrounding grave soil. The results inferred an application of lime depilation and retting, and the Fe-Al compound salt as tanning agent. And it was furthermore implicated that the Fe-Al salt tanning technique had been developed in the middle and late Spring and Autumn Period of China.

  15. The relationship between snack intake and its availability of 4th-6th graders in Taiwan.

    PubMed

    Hang, Chi-Ming; Lin, Wei; Yang, Hsiao-Chi; Pan, Wen-Harn

    2007-01-01

    The purpose of this study was to examine the relationship between the snack intake and snack availability of elementary school children. Data analyzed were from 722 4th to 6th graders' food availability and food intake questionnaires collected in the Nutrition and Health Survey in Taiwan Elementary School Children 2001-2002. The snacks commonly eaten were divided into two groups. Healthy snacks included dairy products, 100% fruit juice and fresh fruits. Unhealthy snacks included high fat/sugar snacks, cookies, candy, carbonated/sugared beverages and fast food. Structural equating modeling was used to test the models that describe the availability and intake of two snack groups. Results indicated that parents' intake and children's preference were major predictors of children intake of both healthy and unhealthy snacks. Other than that, the intake of unhealthy snacks was positively associated with "purchase by children themselves" but not the intake of healthy snacks, which was influenced predominantly by "present in home". The results support the perception that a positive family food environment is important for improving children's diet quality. To build a healthy family food environment, parents have to not only provide healthy snacks but also limit the unhealthy snacks in home. In addition to that, the role modeling of parents as eating healthy snacks instead of unhealthy snacks themselves may help children to develop similar behaviors.

  16. Prevalence of elevated blood pressure in Hispanic versus non-Hispanic 6th graders.

    PubMed

    Tarlton, Patricia A

    2007-02-01

    Blood pressure screening was conducted on 4,311 (Hispanic n = 763 [17.7%], White n = 2,566 [59.5%], African American n = 610 [14.1%], Asian n = 136 [3.2%], Multiracial n = 231 [5.4%], and Native American n = 5 [0.1%]) 6th-grade students enrolled in Seminole County, Florida, Public Schools from August to December 2005. Prevalence of obesity was 21% for the overall population, with Hispanics n = 218 (28.6%) having a greater prevalence than non-Hispanics n = 630 (19.0%). Following a second screening, overall prevalence of elevated blood pressure was 1.9%, with Hispanics at 2.6% versus 1.6% for non-Hispanics. This was found to be significant when Hispanics were further compared to the White population. However, when adjusted for obesity, elevated blood pressure was not significant for Hispanics. Results confirm the presence of elevated blood pressure and obesity in all population groups, with an elevated risk for both among the Hispanic population.

  17. Leather material found on a 6th B.C. Chinese bronze sword: A technical study

    NASA Astrophysics Data System (ADS)

    Luo, Wugan; Si, Yi; Wang, Hongmin; Qin, Ying; Huang, Fengchun; Wang, Changsui

    2011-09-01

    During July to November, 2006, an important archaeological excavation was conducted in Yun country, Hubei province, southern China. Chinese archaeologists found some remnant of leather materials, covered with red pigments, on a 6th century B.C. Chinese bronze sword. To understand the technology/ies that may have been utilized for manufacturing the leathers, a combined of Raman spectroscopy, FT-IR and XRF was thus applied to the remnant of leather materials. Raman analyses showed that red pigment on the leather was cinnabar (HgS). FT-IR and XRF analyses indicated that the content of some elements, such as Ca (existing as CaCO 3) and Fe (existing as Fe 2O 3), were much higher than those in the surrounding grave soil. The results inferred an application of lime depilation and retting, and the Fe-Al compound salt as tanning agent. And it was furthermore implicated that the Fe-Al salt tanning technique had been developed in the middle and late Spring and Autumn Period of China.

  18. FOREWORD: 6th International Symposium on Electronic Beam Ion Sources and their Applications

    NASA Astrophysics Data System (ADS)

    Liljeby, L.

    1997-01-01

    The 6th International Symposium on Electron Beam Ion sources and their Applications was held at the Manne Siegbahn Laboratory at Stockholm University, June 20-23, 1994. A symposium in this series is held every three years. The next one will be organised by Professor Reinhard Becker at the J. W. Goethe University in Frankfurt am Main, Germany. The Stockholm symposium had a total of 65 participants from 9 countries. 43 oral presentations were given and 7 posters were exhibited. For the first time in this series the proceedings have been refereed. The symposium was given generous support by the Marcus Wallbenberg Foundation for International Co-operation in Science, a support mainly used for inviting delegates from Russia and students. The organisation of the symposium was led by Dr. Carl Johan Herrlander. His efficiency, organising skill and never ending attention to all the aspects of the symposium were of the utmost importance for carrying it through. We deeply regret that the proceedings have been very much delayed. Physica Scripta has no part in causing the delay which is solely a result of my inability to enforce deadlines. We think though that the contents still is of interest in particular as a full documentation of the conference.

  19. Proceedings of the 6th US/German Workshop on Salt Repository Research, Design, and Operation

    SciTech Connect

    Hansen, Francis D.; Walter Steininger; Wilhelm Bollingerfehr

    2016-01-11

    The 6th US/German Workshop on Salt Repository Research, Design, and Operation was held in Dresden. Germany on September 7-9, 2015. Over seventy participants helped advance the technical basis for salt disposal of radioactive waste. The number of collaborative efforts continues to grow and to produce useful documentation, as well as to define the state of the art for research areas. These Proceedings are divided into Chapters, and a list of authors is included in the Acknowledgement Section. Also in this document are the Technical Agenda, List of Participants, Biographical Information, Abstracts, and Presentations. Proceedings of all workshops and other pertinent information are posted on websites hosted by Sandia National Laboratories and the Nuclear Energy Agency Salt Club. The US/German workshops provide continuity for long-term research, summarize and publish status of mature areas, and develop appropriate research by consensus in a workshop environment. As before, major areas and findings are highlighted, which constitute topical Chapters in these Proceedings. In total, the scientific breadth is substantial and while not all subject matter is elaborated into chapter format, all presentations and abstracts are published in this document. In the following Proceedings, six selected topics are developed in detail.

  20. PREFACE: The 6th European Conference on Applied Superconductivity (EUCAS 2003)

    NASA Astrophysics Data System (ADS)

    Vaglio, Ruggero; Donaldson, Gordon

    2004-05-01

    This special issue of Superconductor Science and Technology contains papers presented at the 6th European Conference on Applied Superconductivity (EUCAS), which was held in Sorrento, Italy, 14--18 September 2003. This important biennial event followed previous successful meetings held in Gottingen, Germany; Edinburgh, Scotland; Eindhoven, the Netherlands; Sitges (Barcelona), Spain; and Copenhagen, Denmark. Following tradition, this EUCAS conference focused on the role of superconductivity in bridging various aspects of research with a variety of concrete advanced applications. EUCAS 2003 attracted about 1000 participants from all around the world with large participation from non-European countries. This conference benefited the worldwide superconductivity community tremendously as scientists operating internationally were able to share their knowledge and experience with one another. We are grateful to all those who submitted papers to the Conference Proceedings, which will be published in an Institute of Physics Conference Series, and also to those who contributed to this special issue. Unfortunately we could not consider every one of the large number of papers submitted to this issue and we express our regret to those whose work could not be included.

  1. Clinically relevant variants - identifying, collecting, interpreting, and disseminating: the 2013 annual scientific meeting of the Human Genome Variation Society.

    PubMed

    Stanley, Christine M; Sunyaev, Shamil R; Greenblatt, Marc S; Oetting, William S

    2014-04-01

    The dramatic advances in genetic sequencing technologies used in research laboratories are now entering the clinic, and applications of whole-genome and whole-exome sequencing to disease diagnosis, predisposition, and treatment will soon be commonplace. However, the standards and methods for identifying clinically relevant variants are currently being debated and defined. Multiple agencies worldwide have recognized that we have reached an exciting and critical transition point into the clinic, and many important issues are being discussed that impact how genetic variation data in the clinic will be interpreted and used. The 2013 annual scientific meeting of the Human Genome Variation Society (HGVS) had as its main theme the discovery, interpretation, and dissemination of clinically relevant DNA variants. The meeting featured the continuously developing technology of databasing genetic variation and computational tools for allelic variant discovery. Attention was given to curating and integrating these data with clinical findings, including approaches to distinguish between functional alleles underlying clinical phenotypes and benign sequence variants and making data sources interoperable and functional for clinical diagnostic utility, citing examples in specific diseases.

  2. PREFACE: 6th International Workshop on Pseudo-Hermitian Hamiltonians in Quantum Physics

    NASA Astrophysics Data System (ADS)

    Fring, Andreas; Jones, Hugh; Znojil, Miloslav

    2008-06-01

    Attempts to understand the quantum mechanics of non-Hermitian Hamiltonian systems can be traced back to the early days, one example being Heisenberg's endeavour to formulate a consistent model involving an indefinite metric. Over the years non-Hermitian Hamiltonians whose spectra were believed to be real have appeared from time to time in the literature, for instance in the study of strong interactions at high energies via Regge models, in condensed matter physics in the context of the XXZ-spin chain, in interacting boson models in nuclear physics, in integrable quantum field theories as Toda field theories with complex coupling constants, and also very recently in a field theoretical scenario in the quantization procedure of strings on an AdS5 x S5 background. Concrete experimental realizations of these types of systems in the form of optical lattices have been proposed in 2007. In the area of mathematical physics similar non-systematic results appeared sporadically over the years. However, intensive and more systematic investigation of these types of non- Hermitian Hamiltonians with real eigenvalue spectra only began about ten years ago, when the surprising discovery was made that a large class of one-particle systems perturbed by a simple non-Hermitian potential term possesses a real energy spectrum. Since then regular international workshops devoted to this theme have taken place. This special issue is centred around the 6th International Workshop on Pseudo-Hermitian Hamiltonians in Quantum Physics held in July 2007 at City University London. All the contributions contain significant new results or alternatively provide a survey of the state of the art of the subject or a critical assessment of the present understanding of the topic and a discussion of open problems. Original contributions from non-participants were also invited. Meanwhile many interesting results have been obtained and consensus has been reached on various central conceptual issues in the

  3. PREFACE: 6th Workshop on Infrared Spectroscopy and Microscopy with Accelerator-Based Sources (WIRMS11)

    NASA Astrophysics Data System (ADS)

    Lupi, Stefano; Perucchi, Andrea

    2012-05-01

    This volume of Journal of Physics: Conference Series is dedicated to a subset of papers related to the work presented at the 6th edition of the international Workshop on Infrared Spectroscopy and Microscopy with Accelerator-Based Sources (WIRMS), held in Trieste, Italy, September 4-8 2011. Previous editions of the conference were held in Porquerolles (France), Lake Tahoe (USA), Rathen (Germany), Awaji (Japan), and Banff (Canada). This edition was organized and chaired by Stefano Lupi (Roma La Sapienza) and co-chaired by Andrea Perucchi (Elettra), with the support of the Italian Synchrotron Light Laboratory ELETTRA, which was honored to host the WIRMS workshop in its tenth anniversary. The 6th WIRMS edition addressed several different topics, ranging from biochemistry to strongly correlated materials, from geology to conservation science, and from forensics to the study of cometary dusts. Representatives from the infrared scientific programs at synchrotron light sources and free-electron-laser facilities. This edition was attended by 88 participants, including representatives from the infrared scientific programs at synchrotron light sources and free-electron-laser facilities, who enjoyed the stimulating scientific presentations, several detailed discussions, and the beautiful weather and scenery of the Trieste gulf. Participants came from 16 different nations and four continents, including many young scientists, six of which were supported by the organizers. There were 45 scientific talks divided in 11 sessions: Facilities, Microspectroscopy (I, II, III), Time-Resolved Spectroscopies, Extreme Conditions, Condensed Matter, Near-Field, Imaging, THz Techniques and High-Resolution Spectroscopy. 37 posters were also presented at two very lively evening poster sessions. We would like to use the opportunity of writing this preface to thank all the participants of the workshop for the very high level of their scientific contribution and for the very friendly atmosphere

  4. Conference in Rhetorical Criticism: Commended Papers (6th, Hayward, California, May 1, 1971).

    ERIC Educational Resources Information Center

    Peat, Stephen D., Ed.; And Others

    At the sixth annual Cal-State Hayward Conference in Rhetorical Criticism, upper division and graduate students from 11 western colleges and universities presented papers on the theory, history, and criticism of rhetoric. Panels of faculty members from the same colleges and universities selected the three best papers for commendation and…

  5. Noise Pollution, AMA Congress on Environmental Health (6th, Chicago, Illinois, April 28-29, 1969).

    ERIC Educational Resources Information Center

    American Medical Association, Chicago, IL.

    Contained are 15 papers presented at the sixth annual AMA Congress on Environmental Health. Three papers are concerned with noise induced hearing loss as it relates to pathological effects, the role of physicians in workmen's compensation cases, and exposure to steady-state noise. Five papers deal with noise control as it relates to medical…

  6. Gender Representations in the Illustrations of the 6th Grade Language Textbook Used in Greek Elementary School

    ERIC Educational Resources Information Center

    Karintzaidis, Nikolaos; Christodoulou, Anastasia; Kyridis, Argyris; Vamvakidou, Ifigeneia

    2016-01-01

    This study explores the way in which the two sexes are presented in education and particularly in the illustration of the language textbook used in the 6th Grade of Greek elementary school. In a society where gender equality is constitutionally enshrined and displayed as an educational policy objective, it attempts to examine if school textbook…

  7. A Critical Analysis of Academic & Recreational Reading Motivation and Its Correlation to Reading FCAT Performance for 6th Grade Students

    ERIC Educational Resources Information Center

    DiBella, Karen S.

    2014-01-01

    The purpose of this study was to measure the motivation for academic and recreational reading of 6th grade students in a middle school located in southwest Florida using the Elementary Reading Attitude Survey (ERAS). In this mixed methods study, motivation for both types of reading were measured, individual demographics of the population, such as…

  8. Environmental Attitudes of the 6th Grade Students from Rural and Urban Areas: A Case Study for Ankara

    ERIC Educational Resources Information Center

    Tuncer, Gaye; Sungur, Semra; Tekkaya, Ceren; Ertepinar, Hamide

    2004-01-01

    This study investigated environmental attitude of 6th grade students living in rural and urban areas in Ankara. Hundred and thirty-eight students were selected from four schools located in these areas. A 45-item questionnaire consisting of four dimensions was used to measure students' environmental attitude. Results of the study revealed that,…

  9. From Cooks to Carpenters: Measuring - A Saleable Work Skill. Occupation Simulation Packet. Grades 5th-6th.

    ERIC Educational Resources Information Center

    Kennedy, Helena

    This teacher's guide contains simulated work experiences for 5th and 6th grade students using the isolated skill concept - measuring. Teacher instructions include objectives, evaluation, and sequence of activities. The guide contains pre-tests and post-tests with instructions and answer keys. Three pre-skill activities are suggested, such as…

  10. Story Telling: Research and Action to Improve 6th Grade Students' Views about Certain Aspects of Nature of Science

    ERIC Educational Resources Information Center

    Kahraman, Feray; Karatas, Faik Özgür

    2015-01-01

    This study is a four-week section of ongoing attempts that aim to improve 6th grade students' understandings of the nature of science. The study was carried out in a sixth grade science and technology class at a rural middle school with 15 students on the basis of action research methodology. During the study, four different stories based on the…

  11. The Effects of a Traditional and Technology-Based After-School Program on 6th Grade Student's Mathematics Skills

    ERIC Educational Resources Information Center

    Hu, Xiangen; Craig, Scotty D.; Bargagliotti, Anna E.; Graesser, Arthur C.; Okwumabua, Theresa; Anderson, Celia; Cheney, Kyle R.; Sterbinsky, Allan

    2012-01-01

    This study investigated the effectiveness of the Assessment and LEarning in Knowledge Spaces (ALEKS) system as a method of strategic intervention in after-school settings to improve the mathematical skills of struggling 6th grade students. Students were randomly assigned to after-school classrooms in which they either worked with ALEKS to improve…

  12. An Early Warning System: Predicting 10th Grade FCAT Success from 6th Grade FCAT Performance. Research Brief. Volume 0711

    ERIC Educational Resources Information Center

    Froman, Terry; Brown, Shelly; Lapadula, Maria

    2008-01-01

    This Research Brief presents a method for predicting 10th grade Florida Comprehensive Assessment Test (FCAT) success from 6th grade FCAT performance. A simple equation provides the most probable single score prediction, and give-or-take error margins define high and low probability zones for expected 10th grade scores. In addition, a double-entry…

  13. Assessment of 6th Grade Elementary School Students, Their Parents' and Branch Teachers' Perspective on Physical Education Classes

    ERIC Educational Resources Information Center

    Boyraz, Sirin; Ozbar, Nurper; Yetgin, Meral Kucuk; Koksalan, Burke

    2015-01-01

    A total of 437 volunteers including 54 teachers, 218 6th grade students and 102 parents from Beykoz Elementary Schools participated in this study to understand the perspectives of students, families and teachers on Physical Education classes. The perspectives of students, families and teachers of other branches are identified by survey method.…

  14. In vitro Comparative Evaluation of Tensile Bond Strength of 6th, 7th and 8th Generation Dentin Bonding Agents

    PubMed Central

    Kamble, Suresh S; Kandasamy, Baburajan; Thillaigovindan, Ranjani; Goyal, Nitin Kumar; Talukdar, Pratim; Seal, Mukut

    2015-01-01

    Background: Newer dentin bonding agents were developed to improve the quality of composite restoration and to reduce time consumption in its application. The aim of the present study was to evaluate tensile bond strength of 6th, 7th and 8th generation bonding agents by in vitro method. Materials and Methods: Selected 60 permanent teeth were assigned into 20 in each group (Group I: 6th generation bonding agent-Adper SE plus 3M ESPE, Group II: 7th generation bonding agent-G-Bond GC Corp Japan and Group III: 8th generation dentin adhesives-FuturaBond, DC, Voco, Germany). With high-speed diamond disc, coronal dentin was exposed, and selected dentin bonding agents were applied, followed by composite restoration. All samples were saved in saline for 24 h and tensile bond strength testing was done using a universal testing machine. The obtained data were tabulated and statistically analyzed using ANOVA test. Results: The tensile bond strength readings for 6th generation bonding agent was 32.2465, for 7th generation was 31.6734, and for 8th-generation dentine bonding agent was 34.74431. The highest tensile bond strength was seen in 8th generation bonding agent compared to 6th and 7th generation bonding agents. Conclusion: From the present study it can be conclude that 8th generation dentine adhesive (Futura DC, Voco, Germany) resulted in highest tensile bond strength compared to 6th (Adper SE plus, 3M ESPE) and 7th generation (G-Bond) dentin bonding agents. PMID:26028901

  15. SB6.0: The 6th International meeting on Synthetic Biology, July 9-11, 2013

    SciTech Connect

    Kahl, Linda J.

    2015-04-23

    The Synthetic Biology conference series (SBx.0) is the preeminent academic meeting in synthetic biology. Organized by the BioBricks Foundation, the SBx.0 conference series brings together leading researchers, students, industry executives, and policy makers from around the world to share, consider, debate, and plan efforts to make biology easier to engineer. Historically held every two years, the SBx.0 conferences are held in alternating locations in the United States, Europe, and Asia to encourage global participation and collaboration so that the ramifications of synthetic biology research and development are most likely to be safe ethical, and beneficial. On 9-11 July 2013, the 6th installment of the synthetic biology conference series (SB6.0) was held on the campus of Imperial College London (http://sb6.biobricks.org). The SB6.0 conference was attended by over 700 people, and many more were able to participate via video digital conference (http://sb6.biobricks.org/digital-conference/). Over the course of three days, the SB6.0 conference agenda included plenary sessions, workshops, and poster presentations covering topics ranging from the infrastructure needs arising when “Systematic Engineering Meets Biological Complexity” and design-led considerations for “Connecting People and Technologies” to discussions on “Engineering Biology for New Materials,” “Assessing Risk and Managing Biocontainment,” and “New Directions for Energy and Sustainability.” The $10,150 grant awarded by the U.S. Department of Energy (DE-SC0010233) to the BioBricks Foundation was used to provide partial reimbursement for the travel expenses of leading researchers from the United States to speak at the SB6.0 conference. A total of $9,450 was used to reimburse U.S. speakers for actual expenses related to the SB6.0 conference, including airfare (economy or coach only), ground transportation, hotel, and registration fees. In addition, $700 of the grant was used to offset

  16. PREFACE: 6th Vacuum and Surface Sciences Conference of Asia and Australia (VASSCAA-6)

    NASA Astrophysics Data System (ADS)

    Ahsan Bhatti, Javaid; Hussain, Talib; Khan, Wakil

    2013-06-01

    The Vacuum and Surface Sciences Conference of Asia and Australia (VASSCAA) conference series has been organized to create a new forum in Asia and Australia to discuss vacuum, surface and related sciences, techniques and applications. The conference series is officially endorsed by the International Union for Vacuum Science, Technique and Application (IUVSTA). The International Steering Committee of VASSCAA is comprised of Vacuum Societies in seven countries: Australia, China, India, Iran, Japan, South Korea and Pakistan. VASSCAA-1 was organized by the Vacuum Society of Japan in 1999 in Tokyo, Japan. VASSCAA-2 was held in 2002 in Hong Kong, VASSCAA-3 in Singapore in 2005. VASSCAA-4 was held in Matsue, Japan in 2008 and VASSCAA-5 in 2010 in Beijing, China. The 6th Vacuum and Surface Sciences Conference of Asia and Australia (VASSCAA-6) was held from 9-13 October 2012 in the beautiful city of Islamabad, Pakistan. The venue of the conference was the Pak-China Friendship Centre, Islamabad. More than six hundred local delgates and around seventy delegates from different countries participated in this mega event. These delegates included scientists, researchers, engineers, professors, plant operators, designers, vendors, industrialists, businessmen and students from various research organizations, technical institutions, universities, industries and companies from Pakistan and abroad. The focal point of the event was to enhance cooperation between Pakistan and the international community in the fields of vacuum, surface science and other applied technologies. At VASSCAA-6 85 oral presentations were delivered by local and foreign speakers. These were divided into different sessions according to their fields. A poster session was organized at which over 70 researchers and students displayed their posters. The best three posters won prizes. In parallel to the main conference sessions four technical short courses were held. The participants showed keen interest in all these

  17. FAA Forecast Conference Proceedings (6th) Held at Washington, DC on 21 October 1980.

    DTIC Science & Technology

    1980-10-01

    specialized Oper.ratilonis miarkets, i nclur~d ing ra rt icuIa rly,, those that are to a high AN Year agro the FAA prolec -ted that 25) air r . ,rrier...JO Six Annual r 4 . ~FAA Forecast Conference -... Proceedings & u /]-/ " j, Oct8iLC Table of Contents ’.7 I L Part I: Introduction 2 Proceedings...lrowl Ii in FAA workload hig.Inaito ohsrg totti ihhghe o\\ er thle ne\\t 12 years. or)i thle o rder (it 3 piercent per pri( es and othe( r (osts. genieral

  18. PREFACE: NC-AFM 2003: Proceedings of the 6th International Conference on Non-contact Atomic Force Microscopy

    NASA Astrophysics Data System (ADS)

    Reichling, Michael

    2004-02-01

    Direct nanoscale and atomic resolution imaging is a key issue in nanoscience and nanotechnology. The invention of the dynamic force microscope in the early 1990s was an important step forward in this direction as this instrument provides a universal tool for measuring the topography and many other physical and chemical properties of surfaces at the nanoscale. Operation in the so-called non-contact mode now allows direct atomic resolution imaging of electrically insulating surfaces and nanostructures which has been an unsolved problem during the first decade of nanotechnology. Today, we face a most rapid development of the technique and an extension of its capabilities far beyond imaging; atomically resolved force spectroscopy provides information about local binding properties and researchers now develop sophisticated schemes of force controlled atomic manipulation with the tip of the force microscope. Progress in the field of non-contact force microscopy is discussed at the annually held NC-AFM conferences that are part of a series started in 1998 with a meeting in Osaka, Japan. The 6th International Conference on Non-contact Atomic Force Microscopy took place in Dingle, Ireland, from 31 August to 3 September 2003 and this special issue is a compilation of the original publications of work presented at this meeting. The papers published here well reflect recent achievements, current trends and some of the challenging new directions in non-contact force microscopy that have been discussed during the most stimulating conference days in Dingle. Fundamental aspects of forces and dissipation relevant in imaging and spectroscopy have been covered by experimental and theoretical contributions yielding a more detailed understanding of tip--surface interaction in force microscopy. Novel and improved imaging and spectroscopy techniques have been introduced that either improve the performance of force microscopy or pave the way towards new functionalities and applications

  19. [Anniversary of FSI "The 6th Central Military Clinical Hospital of the Ministry of Defense of Russian Federation"].

    PubMed

    Budko, A A; Ovechkin, I G

    2009-08-01

    The 6th Central Military Clinical Hospital of the Ministry of Defense of Russian Federation celebrates the 20th anniversary in September of 2009. The hospital is one of the greatest and well-known in the world specialized science-practical rehabilitation centers, equipped by original and unique methods, based on modern knowledge-intensive technologies. It permits resolve the most difficult tasks of reconstructive treatment of military service men of Russian Army.

  20. The Efficiency of Cluster Method in Improving the Creative Writing Skill of 6th Grade Students of Primary School

    ERIC Educational Resources Information Center

    Sahbaz, Namik Kemal; Duran, Gozde

    2011-01-01

    The aim of this research is to search the effect of the cluster method on the creative writing skill of 6th grade students. In this paper, the students of 6-A, studying at Ulas Primary School in 2010-2011 academic year, were divided into two groups as experiment and control. Taking into consideration the various variants, pre-test and last-test…

  1. Effects of a breeding scheme combined by genomic pre-selection and progeny testing on annual genetic gain in a dairy cattle population.

    PubMed

    Yamazaki, Takeshi; Togashi, Kenji; Iwama, Satoru; Matsumoto, Shigeo; Moribe, Kimihiro; Nakanishi, Takatoshi; Hagiya, Koichi; Hayasaka, Kiyoshi

    2014-06-01

    The effectiveness of the incorporation of genomic pre-selection into dairy cattle progeny testing (GS-PT) was compared with that of progeny testing (PT) where the fraction of dam to breed bull (DB) selected was 0.01. When the fraction of sires to breed bulls (SB) selected without being progeny tested to produce young bulls (YB) in the next generation was 0.2, the annual genetic gain from GS-PT was 13% to 43% greater when h(2)  = 0.3 and 16% to 53% greater when h(2)  = 0.1 compared with that from PT. Given h(2)  = 0.3, a selection accuracy of 0.8 for both YB and DB, and selected fractions of 0.117 for YB and 0.04 for DB, GS-PT produced 40% to 43% greater annual genetic gain than PT. Given h(2)  = 0.1, a selection accuracy of 0.6 for both YB and DB, and selected fractions of 0.117 for YB and 0.04 for DB, annual genetic gain from GS-PT was 48% to 53% greater than that from PT. When h(2)  = 0.3, progeny testing capacity had little effect on annual genetic gain from GS-PT. However, when h(2)  = 0.1, annual genetic gain from GS-PT increased with increasing progeny testing capacity.

  2. PREFACE: 6th International Conference on Inverse Problems in Engineering: Theory and Practice

    NASA Astrophysics Data System (ADS)

    Bonnet, Marc

    2008-07-01

    The 6th International Conference on Inverse Problems in Engineering: Theory and Practice (ICIPE 2008) belongs to a successful series of conferences held up to now following a three-year cycle. Previous conferences took place in Palm Coast, Florida, USA (1993), Le Croisic, France (1996), Port Ludlow, Washington, USA (1999), Angra dos Reis, Brazil (2002), and Cambridge, UK (2005). The conference has its roots on the informal seminars organized by Professor J V Beck at Michigan State University, which were initiated in 1987. The organization of this Conference, which took place in Dourdan (Paris) France, 15-19 June 2008, was made possible through a joint effort by four research departments from four different universities: LEMTA (Laboratoire de Mécanique Théorique et Appliquée, Nancy-Université) LMS (Laboratoire de Mécanique des Solides, Ecole Polytechnique, Paris) LMAC (Laboratoire de Mathématiques Appliquées, UTC Compiègne) LTN (Laboratoire de Thermocinétique, Université de Nantes) It received support from three organizations: SFT (Société Française de Thermique: French Heat Transfer Association) ACSM (Association Calcul de Structures et Simulation : Computational Structural Mechanics Association) GdR Ondes - CNRS (`Waves' Network, French National Center for Scientific Research) The objective of the conference was to provide the opportunity for interaction and cross-fertilization between designers of inverse methods and practitioners. The delegates came from very different fields, such as applied mathematics, heat transfer, solid mechanics, tomography.... Consequently the sessions were organised along mostly methodological topics in order to facilitate interaction among participants who might not meet otherwise. The present proceedings, published in the Journal of Physics: Conference Series, gathers the four plenary invited lectures and the full-length versions of 103 presentations. The latter have been reviewed by the scientific committee (see

  3. Wood - An Innovative Component of High-tech Products? 6th Wädenswil Day of Chemistry 2014.

    PubMed

    Heinzelmann, Elsbeth

    2014-10-01

    Wood is a multifunctional renewable material that could replace oil-based and other non-renewable resources in many applications. In the Swiss National Science Foundation project NFP 66, entitled 'Wood as a resource', researchers are attempting to find ways to use wood more efficiently in the future. The 6th Wädenswil Day of Chemistry, which was organised by the Institute of Chemistry and Biological Chemistry at Zurich University of Applied Sciences in Wädenswil, gave an overview of the innovative activities currently being undertaken in this field.

  4. Childbirth in the Greek island of Chois in the 6th century B.C., 1780, and 1914.

    PubMed

    Argenti, P

    1944-01-01

    Terracottas from the 6th century B.C.; a description of a delivery written in 1780; and a description of a labor chair used until 1914 give an historical picture of childbirth on the Greek island of Chios. The terracottas establish the fact that women were delivered in an upright perpendicular position in classical times. The upright labor chair seems to have continued in use until 1914. Midwives have historically at deliveries. In Chios, doctors seem to have taken over from midwives only around 1914.

  5. PREFACE: 6th Meeting of the Spanish Neutron Scattering Association (SETN2012)

    NASA Astrophysics Data System (ADS)

    2014-11-01

    The bi-annual Meeting of the Spanish Neutron Scattering Association, VI RSETN, took place in the magnificent world heritage ancient city of Segovia, Spain, from 24-27 June 2012, at the historical building ''Palacio de Mansilla''. It was the sixth in a series of successful scientific meetings, beginning in 2002 (San Sebastián), and followed by conferences in Puerto de la Cruz (Canary Islands, 2004), Jaca (Aragón, 2006), Sant Feliú de Guixols (Cataluña, 2008) and Gijón (Asturias, 2010). The conference covered a broad range of topics related to the use of neutron scattering techniques, from soft matter and biosciences to magnetism, condensed matter as well as advanced neutron instrumentation and applications. In addition to those topics, Spanish scientists working at neutron facilities reported recent upgrades of neutron instruments. The VI RSETN was organized by a group of research scientists belonging to different institutions in Madrid: CSIC, Universidad Complutense and Universidad Politécnica de Madrid, in cooperation with the Spanish Society for Neutron Techniques (SETN, 'Sociedad Española de Técnicas Neutrónicas'). The meeting attracted around 90 participants. The total number of oral presentations was 36, including plenary and invited talks, both from domestic and foreign speakers. In addition, the number of posters was around 20. The success of the VI RSETN was due to the efforts of many colleagues involved at all stages of the meeting. We would like to thank the scientific committee, the local organizing committee, the chairs of the conference sessions as well as all the reviewers who agreed generously to help with the process. We would also like to emphasize the excellent scientific quality of all the presentations and posters, and we thank the support received from our sponsors (SETN, ICMM-CSIC, ESS-Bilbao, ILL, Carburos Metálicos), which was really important for the conference success. Finally, we hope that the readers will enjoy the 28

  6. 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability. Whistler, British Columbia, Canada, 14–18 March 2012.

    PubMed

    Nelson, Christopher J; Ausió, Juan

    2012-06-01

    The 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability in Whistler, Canada, 14-18 March 2012, brought together 31 speakers from different nationalities. The organizing committee, led by Jim Davie (Chair) at the University of Manitoba (Manitoba, Canada), consisted of several established researchers in the fields of chromatin and epigenetics from across Canada. The meeting was centered on the contribution of epigenetics to gene expression, DNA damage and repair, and the role of environmental factors. A few interesting talks on replication added some insightful information on the controversial issue of histone post-translational modifications as genuine epigenetic marks that are inherited through cell division.

  7. What predicts the selection of nursing as a career choice in 5th and 6th year school students?

    PubMed

    Neilson, Gavin R; Jones, Martyn C

    2012-07-01

    Demand for nursing care, and nurses, is growing in the United Kingdom given an increasingly ageing patient population with long-term co-morbidities. An ageing nursing workforce and fewer school leavers entering nursing are key barriers to student nurse recruitment. This paper aims to identify the socio-demographic and correlates nursing as a career choice in 5th and 6th year school students. This cross-sectional descriptive study gathered self-administered questionnaires from a total cohort of 5th and 6th year school students (n=1059) in one educational authority in Scotland. A response rate of 100% was achieved, with 702 students expressing a career choice. Some 71.7% (n=503) of students providing a full data set would never consider nursing, even if they obtained poor grades. Only 28.3% (n=199) would ever consider nursing. Students cited nursing as a career choice if they were female, of average to below average academic ability/achievement, expressed a positive attitude to nursing as a degree subject which was shared by their career guidance teacher. Each additional higher reduced the likelihood of nursing as a career choice by 22%. Nursing is an unpopular career choice amongst school students. Strategies are required to improve the occupational image of nursing in secondary education.

  8. Digestive disease management in Japan: a report on the 6th diagnostic pathology summer fest in 2012.

    PubMed

    Ichikawa, Kazuhito; Fujimori, Takahiro; Moriya, Takuya; Ochiai, Atsushi; Yoshinaga, Shigetaka; Kushima, Ryouji; Nagahama, Ryuji; Ohkura, Yasuo; Tanaka, Shinji; Ajioka, Yoichi; Hirata, Ichiro; Tanaka, Masanori; Hoshihara, Yoshio; Kinoshita, Yoshikazu; Sasano, Hironobu; Iwashita, Akinori; Tomita, Shigeki; Hirota, Seiichi; Yao, Takashi; Fujii, Shigehiko; Matsuda, Takahisa; Ueno, Hideki; Ishikawa, Yuichi; Takubo, Kaiyo; Fukushima, Noriyoshi; Sugai, Tamotsu; Iwafuchi, Mitsuya; Imura, Jhoji; Manabe, Toshiaki; Fukayama, Masahisa

    2013-01-01

    The 6th Diagnostic Pathology Summer Fest, held in Tokyo on August 25-26, 2012, opened its gates for everyone in the medical profession. Basic pathology training can contribute to the improvement of algorithms for diagnosis and treatment. The 6th Summer Fest with the theme 'Pathology and Clinical Treatment of Gastrointestinal Diseases' was held at the Ito International Research Center, The University of Tokyo. On August 25, 'Treatment of Early Gastrointestinal Cancer and New Guidelines' was discussed in the first session, followed by 'Biopsy Diagnosis of Digestive Tract: Key Points of Pathological Diagnosis for Inflammation and Their Clinical Significance' in the second session. On August 26, cases were discussed in the third session, and issues on pathological diagnosis and classification of neuroendorcrine tumor in the fourth session. The summaries of speeches and discussions are introduced along with the statements of each speaker. This meeting was not a formal evidence-based consensus conference, and 20 experts gave talks on their areas of specialty. Discussion was focused on how the management strategy should be standardized on the algorithm of patient care.

  9. Is the onset of the 6th century 'dark age' in Maya history related to explosive volcanism?

    NASA Astrophysics Data System (ADS)

    Nooren, Kees; Hoek, Wim Z.; Van der Plicht, Hans; Sigl, Michael; Galop, Didier; Torrescano-Valle, Nuria; Islebe, Gerald; Huizinga, Annika; Winkels, Tim; Middelkoop, Hans; Van Bergen, Manfred

    2016-04-01

    Maya societies in Southern Mexico, Guatemala and Belize experienced a 'dark age' during the second half of the 6th century. This period, also known as the 'Maya Hiatus', is characterized by cultural downturn, political instability and abandonment of many sites in the Central Maya Lowlands. Many theories have been postulated to explain the occurrence of this 'dark age' in Maya history. A possible key role of a large volcanic eruption in the onset of this 'dark age' will be discussed. Volcanic deposits recovered from the sedimentary archive of lake Tuspán and the Usumacinta-Grijalva delta were studied in detail and the combination of multiple dating techniques allowed the reconstruction of the timing of a large 6th century eruption. Volcanic glass shards were fingerprinted to indicate the source volcano and high resolution pollen records were constructed to indicate the environmental impact of the eruption. Results are compared with available archaeological data and causality with the disruption of Maya civilization will be evaluated.

  10. High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research

    PubMed Central

    Reichwald, Kathrin; Lauber, Chris; Nanda, Indrajit; Kirschner, Jeanette; Hartmann, Nils; Schories, Susanne; Gausmann, Ulrike; Taudien, Stefan; Schilhabel, Markus B; Szafranski, Karol; Glöckner, Gernot; Schmid, Michael; Cellerino, Alessandro; Schartl, Manfred; Englert, Christoph; Platzer, Matthias

    2009-01-01

    Background The annual fish Nothobranchius furzeri is the vertebrate with the shortest known life span in captivity. Fish of the GRZ strain live only three to four months under optimal laboratory conditions, show explosive growth, early sexual maturation and age-dependent physiological and behavioral decline, and express aging related biomarkers. Treatment with resveratrol and low temperature significantly extends the maximum life span. These features make N. furzeri a promising new vertebrate model for age research. Results To contribute to establishing N. furzeri as a new model organism, we provide a first insight into its genome and a comparison to medaka, stickleback, tetraodon and zebrafish. The N. furzeri genome contains 19 chromosomes (2n = 38). Its genome of between 1.6 and 1.9 Gb is the largest among the analyzed fish species and has, at 45%, the highest repeat content. Remarkably, tandem repeats comprise 21%, which is 4-12 times more than in the other four fish species. In addition, G+C-rich tandem repeats preferentially localize to centromeric regions. Phylogenetic analysis based on coding sequences identifies medaka as the closest relative. Genotyping of an initial set of 27 markers and multi-locus fingerprinting of one microsatellite provides the first molecular evidence that the GRZ strain is highly inbred. Conclusions Our work presents a first basis for systematic genomic and genetic analyses aimed at understanding the mechanisms of life span determination in N. furzeri. PMID:19210790

  11. Next-generation sequencing detects repetitive elements expansion in giant genomes of annual killifish genus Austrolebias (Cyprinodontiformes, Rivulidae).

    PubMed

    García, G; Ríos, N; Gutiérrez, V

    2015-06-01

    Among Neotropical fish fauna, the South American killifish genus Austrolebias (Cyprinodontiformes: Rivulidae) constitutes an excellent model to study the genomic evolutionary processes underlying speciation events. Recently, unusually large genome size has been described in 16 species of this genus, with an average DNA content of about 5.95 ± 0.45 pg per diploid cell (mean C-value of about 2.98 pg). In the present paper we explore the possible origin of this unparallel genomic increase by means of comparative analysis of the repetitive components using NGS (454-Roche) technology in the lowest and highest Rivulidae genomes. Here, we provide the first annotated Rivulidae-repeated sequences composition and their relative repetitive fraction in both genomes. Remarkably, the genomic proportion of the moderately repetitive DNA in Austrolebias charrua genome represents approximately twice (45%) of the repetitive components of the highly related rivulinae taxon Cynopoecilus melanotaenia (25%). Present work provides evidence about the impact of the repeat families that could be distinctly proliferated among sublineages within Rivulidae fish group, explaining the great genome size differences encompassing the differentiation and speciation events in this family.

  12. Publication of Proceedings for the 6th Workshop on High Energy Density and High Power RF (RF 2003)

    SciTech Connect

    Victor L. Granatstein

    2004-08-08

    The 6th Workshop on High Energy Density and High Power RF (RF 2003) was held from June 22 to June 26 at the Coolfont Resort and Conference Center in Berkeley Springs, West Virginia. The Workshop was hosted by the Institute for Research in Electronics and Applied Physics (IREAP) of the University of Maryland, College Park and by the Naval Research Laboratory, Washington DC. As its name implies this was the sixth in a series of biennial workshops devoted to exchanging information and ideas on high power microwave sources and components. The applications addressed included particle accelerators, radar, HPM, space exploration, neutron sources and plasma heating and current driven in controlled thermonuclear fusion research. This Final Report includes a brief description of the RF 2003 Workshop and the distribution of the published proceedings.

  13. IR and py/GC/MS examination of amber relics excavated from 6th century royal tomb in Korean Peninsula

    NASA Astrophysics Data System (ADS)

    Park, Jongseo; Yun, Eunyoung; Kang, Hyungtae; Ahn, Jooyoung; Kim, Gyuho

    2016-08-01

    Relics of amber were excavated from King Muryeong's tomb constructed in the 6th century on the Korean peninsula. To estimate the provenance, FTIR (Fourier transform infrared spectroscopy) and py/GC/MS (pyrolysis/gas chromatography/mass spectrometry) analysis were utilized. The reference Baltic amber sample was also analyzed with the same method for comparison. The relics were confirmed to be amber from the FTIR analysis where an absorption band near 1150 cm- 1, characteristic one in Baltic amber, was also observed. In py/GC/MS analysis, pyrolyzed products like butanedioic acid and dehydroabietic acid, known constituents of amber, were observed. In addition, D-fenchyl alcohol, camphor, borneol and butanedioic acid, typical constituents of Baltic amber, were observed in some samples. From this, it appears that some of relics were made from Baltic amber and that Baltic amber was transported to the Korean peninsula in the time of tomb construction.

  14. Early fetal gender determination using real-time PCR analysis of cell-free fetal DNA during 6th-10th weeks of gestation.

    PubMed

    Khorram Khorshid, Hamid Reza; Zargari, Maryam; Sadeghi, Mohammad Reza; Edallatkhah, Haleh; Shahhosseiny, Mohammad Hassan; Kamali, Koorosh

    2013-05-07

    Nowadays, new advances in the use of cell free fetal DNA (cffDNA) in maternal plasma of pregnant women has provided the possibility of applying cffDNA in prenatal diagnosis as a non-invasive method. In contrary to the risks of invasive methods that affect both mother and fetus, applying cffDNA is proven to be highly effective with lower risk. One of the applications of prenatal diagnosis is fetal gender determination, which is important in fetuses at risk of sex-linked genetic diseases. In such cases by obtaining the basic information of the gender, necessary time management can be taken in therapeutic to significantly reduce the necessity of applying the invasive methods. Therefore in this study, the probability of detecting sequences on the human Y-chromosome in pregnant women has been evaluated to identify the gender of fetuses. Peripheral blood samples were obtained from 80 pregnant women with gestational age between 6th to 10th weeks and the fetal DNA was extracted from the plasma. Identification of SRY, DYS14 & DAZ sequences, which are not presentin the maternal genome, was performed using Real-Time PCR. All the obtained results were compared with the actual gender of the newborns to calculate the test accuracy. Considerable 97.3% sensitivity and 97.3% specificity were obtained in fetal gender determination which is significant in the first trimester of pregnancy. Only in one case, false positive result was obtained. Using non-invasive method of cffDNAs in the shortest time possible, as well as avoiding invasive tests for early determination of fetal gender, provides the opportunity of deciding and employing early treatment for fetuses at risk of genetic diseases.

  15. BARC 2009 Annual Report TO NC-1037: Genetic and functional genomic approaches to improve production and quality of pork

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The NC-1037 project addresses “Genetic and functional genomic approaches to improve production and quality of pork.” It has 2 objectives: 1) Further understand the dynamic genetic mechanisms that influence production efficiency and quality of pork; and 2) Discover genetic mechanisms controlling anim...

  16. Photometric and Spectroscopic Footprint Corrections in the Sloan Digital Sky Survey’s 6th Data Release

    NASA Astrophysics Data System (ADS)

    Specian, Mike A.; Szalay, Alex S.

    2016-04-01

    We identify and correct numerous errors within the photometric and spectroscopic footprints (SFs) of the Sloan Digital Sky Survey’s (SDSS) 6th data release (DR6). Within the SDSS’s boundaries hundreds of millions of objects have been detected. Yet we present evidence that the boundaries themselves contain a significant number of mistakes that are being revealed for the first time within this paper. Left unaddressed, these can introduce systematic biases into galaxy clustering statistics. Using the DR6 Main Galaxy Sample (MGS) targets as tracers, we reveal inconsistencies between the photometric and SF definitions provided in the Catalog Archive Server (CAS), and the measurements of targets therein. First, we find that 19.7 deg2 of the DR6 photometric footprint are devoid of MGS targets. In volumes of radii 7 {h}-1 {Mpc}, this can cause errors in the expected number of galaxies to exceed 60%. Second, we identify seven areas that were erroneously included or excluded from the SF. Moreover, the tiling algorithm that positioned spectroscopic fibers during and between DRs caused many areas along the edge of the SF to be significantly undersampled relative to the footprint’s interior. Through our corrections, we increase the completeness 2.2% by trimming 3.6% of the area from the existing SF. The sum total of these efforts has generated the most accurate description of the SDSS DR6 footprints ever created.

  17. Bond Strength of 5th, 6th and 7th Generation Bonding Agents to Intracanal Dentin of Primary Teeth

    PubMed Central

    Afshar, Hossein; Baradaran Nakhjavani, Yahya; Rahro Taban, Sedighe; Baniameri, Zahra; Nahvi, Azam

    2015-01-01

    Objectives: This in-vitro study sought to assess the push-out bond strength of a total etch and 2 self-etch bonding systems to intracanal dentin of primary anterior teeth (PAT). Materials and Methods: Thirty-six primary anterior teeth were randomly divided into 3 groups of 5th generation (Single Bond 2), 6th generation (Clearfil SE) and 7th generation (Single Bond Universal) bonding agents. The canal orifice was restored with composite resin and the push-out test was carried out to assess the bond strength. After applying the push-out load, specimens were evaluated under a light microscope at 40X magnification. One-way ANOVA and log-rank test on Kaplan-Meier curves were applied for the comparison of bond strength among the 3 groups. Results: The mean± standard deviation (SD) bond strength was 13.6±5.33 MPa for Single Bond 2, 13.85±5.86 MPa for Clearfil SE and 12.28±5.24 MPa for Single Bond Universal. The differences in bond strength among the 3 groups were not statistically significant (P>0.05). Conclusion: All three bonding agents are recommended for use with composite posts in PAT. However, due to high technical sensitivity of the Total Etch system, single or two-step self etch systems may be preferred for uncooperative children. PMID:26056518

  18. Yersinia pestis DNA from skeletal remains from the 6(th) century AD reveals insights into Justinianic Plague.

    PubMed

    Harbeck, Michaela; Seifert, Lisa; Hänsch, Stephanie; Wagner, David M; Birdsell, Dawn; Parise, Katy L; Wiechmann, Ingrid; Grupe, Gisela; Thomas, Astrid; Keim, Paul; Zöller, Lothar; Bramanti, Barbara; Riehm, Julia M; Scholz, Holger C

    2013-01-01

    Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. These include the third pandemic of the 19(th) and 20(th) centuries, during which plague was spread around the world, and the second pandemic of the 14(th)-17(th) centuries, which included the infamous epidemic known as the Black Death. Previous studies have confirmed that Y. pestis caused these two more recent pandemics. However, a highly spirited debate still continues as to whether Y. pestis caused the so-called Justinianic Plague of the 6(th)-8(th) centuries AD. By analyzing ancient DNA in two independent ancient DNA laboratories, we confirmed unambiguously the presence of Y. pestis DNA in human skeletal remains from an Early Medieval cemetery. In addition, we narrowed the phylogenetic position of the responsible strain down to major branch 0 on the Y. pestis phylogeny, specifically between nodes N03 and N05. Our findings confirm that Y. pestis was responsible for the Justinianic Plague, which should end the controversy regarding the etiology of this pandemic. The first genotype of a Y. pestis strain that caused the Late Antique plague provides important information about the history of the plague bacillus and suggests that the first pandemic also originated in Asia, similar to the other two plague pandemics.

  19. Ethical, legal, and social aspects of farm animal cloning in the 6th Framework Programme for Research.

    PubMed

    Claxton, John; Sachez, Elena; Matthiessen-Guyader, Line

    2004-01-01

    Cloned livestock have potential importance in the provision of improved medicine as well as in the development of livestock production. The public is, however, increasingly concerned about the social and ethical consequences of these advances in knowledge and techniques. There is unevenness throughout Europe in different Member States' attitudes to research into livestock cloning. Although there is EU legislation controlling the use of animals for research purposes, there is no legislation specifically governing cloning in livestock production. The main EU reference is the 9th Opinion of the European Group on Ethics, which states "Cloning of farm animals may prove to be of medical and agricultural as well as economic benefit. It is acceptable only when the aims and methods are ethically justified and when carried out under ethical conditions." The ethical justification includes the avoidance of suffering, the use of the 3Rs principle and a lack of better alternatives. The Commission addresses these issues in the 6th Framework Programme by promoting the integration of ethical, legal and social aspects in all proposals where they are relevant, by fostering ethical awareness and foresight in the proposals, by encouraging public dialogue, and by supporting specific actions to promote the debate. Research must respect fundamental ethical principles, including animal welfare requirements.

  20. The preparatory phase of the April 6th 2009, Mw 6.3, L’Aquila earthquake: Seismological observations

    NASA Astrophysics Data System (ADS)

    Lucente, F. P.; de Gori, P.; Margheriti, L.; Piccinini, D.; Dibona, M.; Chiarabba, C.; Piana Agostinetti, N.

    2009-12-01

    Few decades ago, the dilatancy-diffusion hypothesis held great promise as a physical basis for developing earthquakes prediction techniques, but the potential never become reality, as the result of too few observations consistent with the theory. One of the main problems has been the lack of detailed monitoring records of small earthquakes swarms spatio-temporally close to the incoming major earthquakes. In fact, the recognition of dilatancy-related effects requires the use of very dense network of three-component seismographs, which, in turn, implies the a-priori knowledge of major earthquakes location, i.e., actually a paradox. The deterministic prediction of earthquakes remains a long time, hard task to accomplish. Nevertheless, for seismologists, the understanding of the processes that preside over the earthquakes nucleation and the mechanics of faulting represents a big step toward the ability to predict earthquakes. Here we describe a set of seismological observations done on the foreshock sequence that preceded the April 6th 2009, Mw 6.3, L’Aquila earthquake. In this occasion, the dense configuration of the seismic network in the area gave us the unique opportunity for a detailed reconstruction of the preparatory phase of the main shock. We show that measurable precursory effects, as changes of the seismic waves velocity and of the anisotropic parameters in the crust, occurred before the main shock. From our observations we infer that fluids play a key role in the fault failure process, and, most significantly, that the elastic properties of the rock volume surrounding the main shock nucleation area undergo a dramatic change about a week before the main shock occurrence.

  1. [The IASLC lung cancer staging project. Comparing the current 6(th) TNM edition with the proposed 7(th) edition].

    PubMed

    Carvalho, Lina; Cardoso, Edgar; Nunes, Henrique; Baptista, Victor; Gomes, Ana; Couceiro, Patrícia

    2009-01-01

    The future 7th edition of TNM classification for lung cancer will be published in 2009 and comprises the IASLC recommendations for TNM parameters. The general staging of lung cancer includes the new parameters: reclassification of tumours larger than 7 cm from T2 to T3; extra tumoral nodules will change their category to T3, T4 and M1 when in the same, ipsilateral or contralateral lobe, respectively; pleural effusion will be M1a. With these alterations, cases staged as IB - T2b N0 M0 will be IIA, cases staged IIB - T2a N1 M0 will be IIA and cases IIIB- T4 N0- -1 M0 will be IIIA. The 7(th) TNM edition recommendations were applied to 203 broncho -pulmonary carcinomas, concerning epidermoid carcinomas (83) and adenocarcinomas (120) registered in the archive of the Serviço de Anatomia Patológica of the Hospitais da Universidade de Coimbra - Portugal, previously submitted to surgical resection and lymph node excision. The following alterations will be kept as the application of the future 7(th) TNM edition: 20 cases in stage IB will move to stage IIA (17) and stage IIB (3); 18 cases will change from stage IIB to stage IIA (17) and 1 case to stage IIIA; 2 cases from stage IIIB will move to stage IV; 6 cases in stage IV will move to stage IIIA (5) and 1 case to stage IIIB. In this translational adaptation from 6th to 7th TNM staging, 51 out of the 203 analysed cases change their staging, corresponding to 25.1%.

  2. Brick and Click Libraries: Proceedings of an Academic Library Symposium (6th, Maryville, Missouri, November 3, 2006)

    ERIC Educational Resources Information Center

    Baudino, Frank, Ed.; Ury, Connie Jo, Ed.; Park, Sarah G., Ed.

    2006-01-01

    These proceedings document the sixth year of the "Brick and Click Libraries Symposium," held annually at Northwest Missouri State University in Maryville, Missouri, on November 3, 2006. Thirty-four peer-reviewed papers and abstracts, written by academic librarians, and presented at the symposium are included in this volume. Many of the…

  3. The Hetu'u Global Network: Measuring the Distance to the Sun Using the June 5th/6th Transit of Venus

    ERIC Educational Resources Information Center

    Faherty, Jacqueline K.; Rodriguez, David R.; Miller, Scott T.

    2012-01-01

    In the spirit of historic astronomical endeavors, we invited school groups across the globe to collaborate in a solar distance measurement using the rare June 5/6th transit of Venus. In total, we recruited 19 school groups spread over 6 continents and 10 countries to participate in our Hetu'u Global Network. Applying the methods of French…

  4. Trends in Substance Use among 6th-to 10th-Grade Students from 1998 to 2010: Findings from a National Probability Study

    ERIC Educational Resources Information Center

    Brooks-Russell, Ashley; Farhat, Tilda; Haynie, Denise; Simons-Morton, Bruce

    2014-01-01

    Of the handful of national studies tracking trends in adolescent substance use in the United States, only the Health Behavior in School-Aged Children (HBSC) study collects data from 6th through 10th graders. The purpose of this study was to examine trends from 1998 to 2010 (four time points) in the prevalence of tobacco, alcohol, and marijuana use…

  5. The Effect of the Van Hiele Model Based Instruction on the Creative Thinking Levels of 6th Grade Primary School Students

    ERIC Educational Resources Information Center

    Erdogan, Tolga; Akkaya, Recai; Celebi Akkaya, Sibel

    2009-01-01

    The aim of this study is to determine the effect of the Van Hiele model based instruction process on the creative thinking levels of 6th grade primary school students. Pre test-post test matching control group quasi-experimental design was used in the study. Fifty five students enrolled in sixth grades during the 2005-2006 educational year formed…

  6. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (6th, Ellenville, New York, March 18-20, 1992).

    ERIC Educational Resources Information Center

    Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

    This conference proceedings report includes: (1) "Grading Papers More Objectively and Effectively," by Anita M. Meehan; (2) "The Use of Student Workbooks in Introductory Psychology Courses," by Donna L. Reittinger and Kathleen Crowley-Long; (3) "Curriculum Integration and Cross-Cultural Psychology," by Susan B.…

  7. The Role of the Computer in Education. Proceedings of the Annual Meeting (6th, Arlington Heights, Illinois, February 12-14, 1986).

    ERIC Educational Resources Information Center

    Micro-Ideas, Glenview, IL.

    Fifty-five papers focusing on the role of computer technology in education at all levels are included in the proceedings of this conference, which was designed to model effective and appropriate uses of the computer as an extension of the teacher-based instructional system. The use of the computer as a tool was emphasized, and the word processor…

  8. Education and Equity in Rural America: 1984 and Beyond. Proceedings of the Annual Rural and Small Schools Conference (6th, Manhattan, Kansas, October 29-30, 1984).

    ERIC Educational Resources Information Center

    Horn, Jerry, Ed.; Davis, Patricia, Ed.

    The proceedings consist of the entire major addresses of Senator Nancy Landon Kassebaum, Steve Miller, and Walter Turner, and abbreviated versions of 29 other papers or presentations. The materials deal with a variety of rural-focused topics: women (Evelyn Hausmann); teacher career ladder plans (Paul Burden); inservice (Robert Norton, Myron…

  9. Annual report of the National Advisory Committee for Aeronautics (6th).administrative report including Technical Reports nos. 83 to 110

    NASA Technical Reports Server (NTRS)

    1921-01-01

    Report includes the National Advisory Committee for Aeronautics letter of submittal to the President, Congressional report, summaries of the committee's activities and research accomplished, expenditures, House of Representatives bill 14061, a copy of the bill introduced to the House of Representatives to regulate air navigation, and a compilation of technical reports produced.

  10. The Promise of Technology. Proceedings of the Annual Conference on Rehabilitation Engineering (6th, San Diego, California, June 12-16, 1983). Volume 3.

    ERIC Educational Resources Information Center

    Bowman, Bruce R., Ed.

    These proceedings contain abstracts of 164 papers in the area of interdisciplinary rehabilitation research, focusing on the theme of "The Promise of Technology." The abstracts are organized into the following sections: "Home and Worksite Modification,""Computers and Microprocessor Systems,""Neuromuscular…

  11. Extending the Human Mind: Computers in Education. Program and Proceedings of the Annual Summer Computer Conference (6th, Eugene, Oregon, August 6-9, 1987).

    ERIC Educational Resources Information Center

    Oregon Univ., Eugene. Center for Advanced Technology in Education.

    Presented in this program and proceedings are the following 27 papers describing a variety of educational uses of computers: "Learner Based Tools for Special Populations" (Barbara Allen); "Micros and Mainframes: Practical Administrative Applications at the Building Level" (Jeannine Bertrand and Eric Schiff); "Logo and Logowriter in the Curriculum"…

  12. Health Care Ethics: Dilemmas, Issues and Conflicts. Midwest Alliance in Nursing Annual Fall Workshop (6th, Indianapolis, Indiana, September 5-6, 1985).

    ERIC Educational Resources Information Center

    Prock, Valencia N., Ed.; And Others

    A variety of ethical issues confronting the nursing profession are examined in these proceedings. The following papers are presented: (1) "Ethics: Care & Conflict," by Leah Curtin; (2) "The Interface of Politics and Ethics in Nursing," by Mila Aroskar; (3) "Pluralistic Ethical Decision-Making," by Rita Payton; (4)…

  13. Pacific Circle Consortium: A Regional Project of OECD/CERI. Report of Annual Conference (6th, Hiroshima, Japan, September 27-October 4, 1982).

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France). Centre for Educational Research and Innovation.

    Pacific region countries reported on their 1982 cooperative activities in education, including exchange and curriculum development projects, aimed at improving intercultural understanding. The first part of the report describes what happened at the sessions; the second part contains the appendices. Various countries--Australia, Canada, Japan, New…

  14. Research, Issues, and Practices. Annual Curriculum and Instruction Research Symposium Conference Proceedings, University of South Dakota (6th, Vermillion, SD, April 24, 1998).

    ERIC Educational Resources Information Center

    Wood, Robert W., Ed.; Hoag, Constance L., Ed.; Zalud, Garreth, Ed.

    This report includes papers from a 1998 symposium to promote the professional sharing of current educational issues. The papers are: "A Tapestry of Authors" (Maurine Richardson and Margaret Miller); "Critical Thinking Strategies Across the Curriculum" (Constance L. Hoag and Sharon Andrews); "The Effect of Journal Writing…

  15. Languages and Communication for World Business and the Professions. Proceedings of the Annual Conference (6th, Ann Arbor, Michigan, May 8-9, 1987).

    ERIC Educational Resources Information Center

    Des Harnais, Gaston R., Ed.

    Topics covered in papers presented at a conference on languages and communication for world business and the professions include: (1) trends and aspects of internationalizing the business curriculum; (2) internationalized programs in business, foreign language, and cultures; (3) internationalized courses in business, foreign languages, and…

  16. Non-Traditional and Interdisciplinary Programs. Proceedings from the Annual Conference (6th, Virginia Beach, Virginia, April 25-27, 1988).

    ERIC Educational Resources Information Center

    Reithlingshoefer, Sally J., Ed.; Sanford, James F., Ed.

    A total of 72 papers on nontraditional and interdisciplinary programs are presented in 11 tracks: (1) Assessing Learning Outcomes and Providing Quality in Non-Traditional Degree Programs (8 papers, including "Assessing the Quality of a Non-Traditional Degree Program: A Case Study," by Solomon Deressa and Mary Sue Simmons); (2) Consortial,…

  17. Proceedings of the Annual Precise Time and Time Interval (PTTI) Planning Meeting (6th). Held at U.S. Naval Research Laboratory, December 3-5, 1974

    DTIC Science & Technology

    1974-01-01

    business. But I steel myself to believe that you can’t hurt yourself by knowing what is going on. And so I insisted on understanding the business in...against the frontiers here. I heard someone talking 10IS. Heck, I am just as willing to talk 1024. Why set your goals low ? I had some of my...characteristics that are essentially fundamental to microwave satellite optical and wired technologies can be developed and easily put into place. We

  18. EXCELLENCE IN CONTINUING EDUCATION, PROCEEDINGS OF THE ANNUAL JUNIOR COLLEGE ADMINISTRATIVE TEAMS INSTITUTE (6TH, UNIVERSITY OF FLORIDA, GAINESVILLE, AUGUST 7-9, 1966).

    ERIC Educational Resources Information Center

    Florida State Univ., Tallahassee.

    THE GROWING INTEREST IN CONTINUING EDUCATION ON THE LOCAL, STATE, AND NATIONAL LEVELS APPEARS RELATED TO (1) THE IMPROVING EDUCATIONAL LEVEL OF THE GENERAL POPULATION, (2) THE CHANGING AND INCREASINGLY COMPLEX WORLD, (3) INCREASING LEISURE, AND (4) THE RISING STANDARD OF LIVING. RESEARCH INDICATES THAT (1) FEW COLLEGES EMPLOY ADULT EDUCATION…

  19. Health Promotion: Contributions of Nursing; Benefits for Clients. Midwest Alliance in Nursing Annual Program Meeting (6th, St. Louis, Missouri, April 18-19, 1985).

    ERIC Educational Resources Information Center

    Minckley, Barbara B., Ed.; Young, Lu Ann, Ed.

    Focusing on innovative and cost-effective alternatives to traditional, custodial, and institutional health care systems, the papers in these proceedings identify the contributions of nursing and the benefits for patients of the new national emphasis on cost-effective health care. The proceedings contain: (1) "Trends in Health Promotion:…

  20. Proceedings of the Annual RAND-China Reform Forum Conference (6th) Held in Santa Monica, California on August 28-29, 2003

    DTIC Science & Technology

    2005-01-01

    support. The SOEs have easy access to bank funds and they face no threat of bankruptcy . The key rationale of the soft budget policy is that bankrupting ...loans on the books rather than letting the borrowers go bankrupt , because the bankruptcy laws do not protect the banks, and the banks usually end up...commercial modes. Those industries and enterprises suffering from SARS take measures to self-rescue and avoid bankruptcy . Fourthly, the Chinese

  1. Broadening Participation in Science, Technology and Medicine: Proceedings of the Annual Technological Literacy Conference (6th, Washington, D.C., February 1-3, 1991).

    ERIC Educational Resources Information Center

    Cheek, Dennis W., Ed.

    This document contains the text of 50 papers presented at a national conference that focused on the relationships among science, technology, and society (STS). Most of the papers presented featured one of five major thematic areas around which the National Association for Science, Technology and Society is organized: education and information;…

  2. Proceedings for the Annual Conference of the NASSGP/NCHELP Research Network (6th, Washington, D.C., June 7-9, 1989).

    ERIC Educational Resources Information Center

    Davis, Jerry S., Ed.

    This proceedings contains 25 papers, the conference agenda, and summaries of other presentations of a 1989 conference on student financial aid. The following papers are included: "Minorities in Higher education in the 1970s and 1980s-What the Current Population Surveys Tell Us" (Paul M. Siegel); "Estimating Minority Participation in…

  3. Optimizing Learning. Proceedings of the Annual Society for the Advancement of Gifted Education Conference (6th, Edmonton, Alberta, Canada, September 29-30, 1995).

    ERIC Educational Resources Information Center

    Society for the Advancement of Gifted Education, Calgary (Alberta).

    This conference proceedings focuses on structuring classrooms to optimize learning among Alberta (Canada) gifted students. The first paper, "Optimizing Parent Potential" (Trudy A. Harrold), describes a model and a process for helping parents acquire knowledge, organize their thinking, and act from a realistic base when dealing with their gifted…

  4. Speeches Presented at the Annual National Leadership Development Seminar for State Directors of Vocational Education. (6th, Nashville, Tennessee, September 18-21, 1973).

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    Following a welcoming address by the Governor of Tennessee, fifteen speeches were presented at the seminar. W. H. Pierce examined approaches to educational governance at the State level. Management, its efficiency, effectiveness, and organization, was the topic of several speeches (J. D. Mills, D. K. Gentry and C. F. Lamar). The development of…

  5. Proceedings of the Annual RAND-China Reform Forum Conference (6th) Held in Beijing, China on August 28-29, 2003

    DTIC Science & Technology

    2005-01-01

    Bijian Zheng and Charles Wolf, Jr. William Overholt, Angang Hu, Edward Leamer, Renwei Huang, Benjamin Zycher, Yuanlong Wang , K.C. Yeh, Fanzhang...Huang, John Despres, Gary Hufbauer, Harold Brown, Jisi Wang Approved for public release; distribution unlimited The RAND Corporation is a nonprofit...47 “The Status Quo and Prospect of China’s Banking Industry” by Wang Yuanlong

  6. Proceedings of the Annual Rand-China Reform Forum Conference (6th) held in Santa Monica, California on 28-29 August 2003

    DTIC Science & Technology

    2005-01-01

    Hu, Edward Leamer, Renwei Huang, Benjamin Zycher, Yuanlong Wang , K.C. Yeh, Fanzhang Huang, John Despres, Gary Hufbauer, Harold Brown, Jisi Wang ...China’s Banking Industry” by Wang Yuanlong..............................................................53 “China’s Financial Sector: Challenges and...by Dr. Harold Brown...............................137 “New Elements In China-U.S. Strategic Relations” by Wang Jisi........141 ix AGENDA Conference

  7. Reservation School Districts. Report of the Annual Indian Town Hall (6th, White Mountain Apache Reservation, Arizona, December 6-7, 1978).

    ERIC Educational Resources Information Center

    Arizona Commission of Indian Affairs, Phoenix.

    Forty-four representatives of American Indian tribes and the state of Arizona participated in the 2-day conference on reservation school districts. Terrance Leonard explained the legislative history and workings of Johnson-O'Malley funding, described supplementary Johnson-O'Malley programs, and commented on the Indian Education Act. Dr. Kenneth…

  8. Proceedings of the Symposium on the Role of Behavioral Science in Physical Security (6th Annual) Held at Springfield, Virginia, 3-4 June l981

    DTIC Science & Technology

    1983-11-16

    411-187.) Kidd, J.S., Kidd and Hooper, J.J., "Division of Responsibility Between Two Controllers and Load Balancing Flexibility in a Radar Approach...and training effectiveness analysis (CTEA)3 methods. The product would be a recommended, balanced , long-range training development program...Successful investigations require the balancing of the individual rights of sus- pects against the need to protect key persons and facilities. This is not an

  9. Perfecting and Understanding Roles in Education. Proceedings of the Annual National Conference of People United for Rural Education (6th, Des Moines, Iowa, February 3-4, 1983).

    ERIC Educational Resources Information Center

    People United for Rural Education, Alden, IA.

    Proceedings of the 1983 People United for Rural Education conference are developed around the theme of "Perfecting and Understanding Roles in Education." Following the introductory materials are 12 papers which were presented at the meeting. Major addresses and authors include: "A Federal Perspective for Excellence in Rural…

  10. Proceedings of the Association for Unmanned Vehicle Systems AUVS 󈨓 Annual Convention (6th) Held in San Diego, California on May 29 - June 1, 1979

    DTIC Science & Technology

    1979-01-01

    across many applications. The second shortcoming was the resulting and inappro- priate emphasis on vehicle mobility and control. These features of...increased tank firepower), (2) be able to move or be moved lcg distances faster than tanks (increased fire- power mobility ), and (3) allow tanks te...weapons system and their impact on battlefield capabilities. Vi There has been no discussion of mobility of the remote subsystem. However, Stwo kinds

  11. Canadian Association for the Study of Adult Education. Proceedings of the Annual Conferences (6th, Hamilton, Ontario, Canada, May 29-31, 1987).

    ERIC Educational Resources Information Center

    Gillen, Marie A., Ed.; Burkholder, Avon, Ed.

    These proceedings contain 14 papers and notes from 2 symposia in English and 2 papers in French. Abstracts appear at the beginning of the volume. The following papers are included: "Symposium Notes: What Is the Future of Adult Education in Canada?" (Bernard, MacNeil, Selman); "John Dewey Dialogues with an Adult Educator in…

  12. Integration of physical activity and technology motion devices within a combined 5th and 6th grade science curriculum

    NASA Astrophysics Data System (ADS)

    Finn, Kevin Eugene

    Background: National recommendations to increase school-based physical activity and promote academic success advise incorporating movement into traditional classroom lessons. Classroom-based physical activities have favorable associations with indicators of cognitive functioning, academic behaviors, and academic achievement. Purpose: This study analyzed the Active Science framework, which incorporated school-based physical activity within interactive science classroom lessons. Specifically, the study measured the effects of the Active Science framework on student physical activity levels in the classroom, student learning of science inquiry skills and content knowledge, and student perceptions of physical activity and science. A secondary purpose was to evaluate the teachers' perceptions on the implementation of the framework. Subjects: Participants were 37 Hispanic girls (age=11.1 +/-0.8 yr) in mixed 5th/6th grade science classes in a private, urban middle school. Methods: Physical activity levels of the students during the Active Science framework were measured using pedometers and heart rate monitors. Pre- and post-tests were used to assess the levels of learning achieved by the students in science inquiry skills and content during the Active Science framework. Student perceptions and attitudes toward science and physical activity were measured during student focus groups and pre-post perception surveys. Lesson plan evaluations completed by the teachers and structured interviews provided data on implementation of the framework. Results: Physical activity results showed heart rate (146 +/-9 bpm); maximal heart rate (196 +/-10.6 bpm); time (35 +/-2.5 mins); steps (3050 +/-402.7); calories (99 +/-8.4 kcal); and distance (1.1 +/-0.2 miles) while performing the activity portion of the science lessons were consistent with national recommendations for accumulating school-based physical activity. Significant increases in science content and skills test scores with a 22

  13. Bone loss during partial weight bearing (1/6th gravity) is mitigated by resistance and aerobic exercise in mice

    NASA Astrophysics Data System (ADS)

    Boudreaux, R. D.; Metzger, C. E.; Macias, B. R.; Shirazi-Fard, Y.; Hogan, H. A.; Bloomfield, S. A.

    2014-06-01

    Astronauts on long duration missions continue to experience bone loss, as much as 1-2% each month, for up to 4.5 years after a mission. Mechanical loading of bone with exercise has been shown to increase bone formation, mass, and geometry. The aim of this study was to compare the efficacy of two exercise protocols during a period of reduced gravitational loading (1/6th body weight) in mice. Since muscle contractions via resistance exercise impart the largest physiological loads on the skeleton, we hypothesized that resistance training (via vertical tower climbing) would better protect against the deleterious musculoskeletal effects of reduced gravitational weight bearing when compared to endurance exercise (treadmill running). Young adult female BALB/cBYJ mice were randomly assigned to three groups: 1/6 g (G/6; n=6), 1/6 g with treadmill running (G/6+RUN; n=8), or 1/6 g with vertical tower climbing (G/6+CLB; n=9). Exercise was performed five times per week. Reduced weight bearing for 21 days was achieved through a novel harness suspension system. Treadmill velocity (12-20 m/min) and daily run time duration (32-51 min) increased incrementally throughout the study. Bone geometry and volumetric bone mineral density (vBMD) at proximal metaphysis and mid-diaphysis tibia were assessed by in vivo peripheral quantitative computed tomography (pQCT) on days 0 and 21 and standard dynamic histomorphometry was performed on undemineralized sections of the mid-diaphysis after tissue harvest. G/6 caused a significant decrease (P<0.001) in proximal tibia metaphysis total vBMD (-9.6%). These reductions of tibia metaphyseal vBMD in G/6 mice were mitigated in both G/6+RUN and G/6+CLB groups (P<0.05). After 21 days of G/6, we saw an absolute increase in tibia mid-diaphysis vBMD and in distal metaphysis femur vBMD in both G/6+RUN and G/6+CLB mice (P<0.05). Substantial increases in endocortical and periosteal mineralizing surface (MS/BS) at mid-diaphysis tibia in G/6+CLB demonstrate that

  14. Conference scene: Summary of the 6th Conference of the Romanian Association of Medical Laboratories with international participation.

    PubMed

    Carasevici, Eugen

    2011-10-01

    The Romanian Association of Medical Laboratories (RAML) conferences have acquired a reputation for standing out as the most prominent and efficient meetings in the national community of laboratory medicine, being a landmark of the development in this field in Romania and an active affiliation to international forums. This year, the conference setting was Piatra Neamt, in the northeast part of Romania, which produced a friendly and stimulating professional environment. As in previous years, leading experts in the fields of laboratory medicine attended the event. This year, we enjoyed the opportunity to have such distinguished guests as the members of the executive board of International Federation of Clinical Chemistry and Laboratory Medicine (IFCC); Graham Beastall, IFCC President; Päivi Hannele Laitinen, IFCC secretary; and Grazyna Sypniewska, IFCC Communication and Publication Division, and editor of the electronic journal of the IFCC. As usual, the conference program included all aspects of clinical laboratory activity, with a special focus on technology development, instrumentation and laboratory management. Fully aware of the fact that the complexity and depth of laboratory practice have undergone an impressive and rapid evolution, the specific goals of the event were to increase knowledge in the fundamentals of new molecular investigation, areas which show the tendency to become routine in our daily activity. In addition, laboratory management and the place of medical laboratories in the process of translational medicine were subjects of focus. The 6th Conference of the Romanian Association of Medical Laboratories was held from Wednesday 1st to Saturday 4th of June 2011. A total of 273 participants from all local branches of the Association attended. The scientific program included seven plenary sessions where 22 lectures and 18 short communications were delivered, and three poster sessions with 44 poster presentations. Session topics covered issues of

  15. 78 FR 8183 - Address Change for Filing Annual Election to Average for Motor Vehicles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... SECURITY U.S. Customs and Border Protection Address Change for Filing Annual Election to Average for Motor... Trade, U.S. Customs and Border Protection, for filing annual election to average for motor vehicles. The..., 1717 H Street NW., (6th Floor), Washington, DC 20229-1141. Telephone number: 202-325-7960. Fax...

  16. Update on the U.S. Army TARDEC Power and Energy P&E SIL Program: Progress since the 6th AECV (June 2005 to Present)

    DTIC Science & Technology

    2007-06-01

    energy dissipaters were installed and the diagnostics and data acquisition system was upgraded. Since one of the two traction motor- dyno pairs was...ion system identical to one installed in HERMIT. New energy dissipaters were installed and the diagnostics and data acquisition system was upgraded...UPDATE ON THE U.S. ARMY TARDEC POWER AND ENERGY P&E SIL PROGRAM Progress since the 6th AECV (June 2005 to Present) Nancy Saxon*, Eugene

  17. Prognostic Discrepancy of the 6th and 7th UICC N Classification for Lymph Node Staging in Gastric Cancer Patients after Curative Resection

    PubMed Central

    Oh, Sung Jin; Suh, Byoung Jo; Park, Jong Kwon; Oh, Sung Don; Yu, Hang Jong

    2017-01-01

    Background The validity of N classification of the 7th edition of the American Joint Committee on Cancer/Union Internationale contre le Cancer (AJCC/UICC) tumor-node-metastasis (TNM) staging system is still under debate. The purpose of this study was to evaluate the prognostic efficacy of the 7th edition of the AJCC/UICC TNM staging system (focusing on N stage), in comparison with the 6th edition, at a single Eastern institution. Methods We analyzed 1,435 patients with gastric cancer who underwent curative resection performed from September 1998 to August 2003 at the Memorial Jin-Pok Kim Korea Gastric Cancer Center. We analyzed the survival rate of the patients according to the AJCC/UICC 6th and 7th editions, and compared each stage, focusing on N stage. Results Significant differences in the 5-year survival rates were observed between the 6th and the 7th AJCC/UICC staging system. In the 6th edition staging system, the Kaplan-Meier curves discriminated each N stage significantly. In contrast, there was no difference in terms of survival curves for N stage according to the 7th edition, especially between N1 and N2: the Kaplan-Meier plots of survival curves between N1 (77.0%) and N2 (78.1%) stages overlapped significantly (p < 0.05). Conclusion Although the 7th UICC staging system is a more detailed and sophisticated system in the T category, there was no prognostic significance between the pN1 and pN2 stages according to our data. Therefore, we suggest establishing a new UICC staging system taking into consideration the application of the N stage. PMID:28203165

  18. Breaching the Devil’s Garden- The 6th New Zealand Brigade in Operation Lightfoot. The Second Battle of El Alamein, 23 October 1942. Appendices

    DTIC Science & Technology

    2006-02-01

    Force (And Related Elements) Appendix K Chronology Of Events, 6th New Zealand Brigade Zone Appendix L Other Breaches Conducted As Part Of The Overall...extra positions will be used as alternate positions. All new positions will be placed in the minefields. A part of each combat outpost, in the old...Aber auch den eing6e3etztefl Verbaenden wfrd si ~ch txn~itteltsaz l4ntor der - Front Gelegenhoit bieten, in beochraenktom Rahmen eauszibilden

  19. Archeomagnetic Intensity Variations During the 6th Millennium BC in the Middle East: New Data from Yarim Tepe II (Northern Iraq)

    NASA Astrophysics Data System (ADS)

    Akimova, S.; Gallet, Y.; Amirov, S.

    2015-12-01

    During the seventies, Soviet archeologists conducted in Northern Iraq excavations of several ancient settlements dated from the Pottery Late Neolithic period (7th and 6th millennia BC). A very large collection of artifacts unearthed from these sites, in particular several thousands of well-documented pottery fragments, is now stored at the Archeological Institute in Moscow. We collected a time-sequential series of groups of potsherds from the multilayered settlement called Yarim Tepe II dated to the Halaf period (6th millennium BC). Each group comprises a minimum of 3 potsherds (up to 10) found within a same archeological layer, typically a thickness of about 20 cm. Altogether, the fragment groups encompass the entire 7-m thick stratigraphic sequence of Yarim Tepe II. We will present our first archeointensity results obtained using the experimental protocol developed for the Triaxe magnetometer, taking into account the effects of both the thermoremanent magnetization (TRM) anisotropy and the cooling rate dependence on TRM acquisition. The new data help to better constrain the geomagnetic field intensity variations in the Middle East during the 6th millennium BC. Thanks to the comparison with other datasets from Bulgaria and Syria, the new archeointensity results provide evidence for the occurrence of very rapid geomagnetic field intensity variations around 5500 BC.

  20. Smoking practices, risk perception of smoking, and environmental tobacco smoke exposure among 6th-grade students in Ciudad Juárez, Mexico.

    PubMed

    Bird, Yelena; Moraros, John; Olsen, Larry K; Forster-Cox, Sue; Staines-Orozco, Hugo; Buckingham, Robert W

    2007-02-01

    This study assessed the smoking practices, risk perception of smoking, and environmental tobacco smoke (ETS) exposure among adolescents in Ciudad Juárez, Mexico. We used a cross-sectional method to examine the smoking practices, risk perception of smoking, and ETS exposure of 6th-grade students (N=506), aged 11-13 years, attending six randomly selected middle schools. Schools were classified by school setting (i.e., public vs. private) and socioeconomic status (SES; i.e., low, middle, or high). The results indicated that 6th-grade students attending a public, low-SES school setting in Ciudad Juárez not only exhibited significantly higher rates of ETS exposure at home and in public places (p<.01) but also were more likely to have tried smoking (p<.01) and to be current smokers (p<.01), and were less likely to support a ban on smoking in public places (p<.01), compared with students who attended a private school or a public, middle- or high-SES school setting. These results provide further evidence that public health interventions to prevent initiation of smoking and to assist in smoking cessation among adolescents and to reduce their ETS exposure at home and in public need to target all school-aged students, especially those attending school in a low-SES settings.

  1. Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best lymph node classification for esophageal cancer? Prognosis factor analysis in 487 patients

    PubMed Central

    CORAL, Roberto V.; BIGOLIN, André V.; CORAL, Roberto P.; HARTMANN, Antonio; DRANKA, Carolina; ROEHE, Adriana V.

    2015-01-01

    Background The esophageal cancer is one of the most common and aggressive worldwide. Recently, the AJCC changed the staging system, considering, among others, the important role of the lymph node metastasis on the prognosis. Aim To discuss the applicability of different forms of lymph node staging in a western surgical center. Methods Four hundred eighty seven patients with esophageal cancer were enrolled. Three staging systems were evaluated, the 6th and the 7th AJCC editions and the Lymph Node Metastatic Ratio. Results The majority of the cases were squamous cell carcinoma. The mean lymph node sample was eight. Considering the survival, there was no significant difference between the patients when they were classified by the 7th AJCC edition. Analysis of the Lymph Node Metastatic Ratio, just on the group of patients with 0 to 25%, has shown significant difference (p=0,01). The 6th AJCC edition shows the major significant difference between among the classifications evaluated. Conclusion In this specific population, the 7th AJCC edition for esophageal cancer was not able to find differences in survival when just the lymph node analysis was considered. PMID:26176242

  2. Rabies vaccine standards: comparison of the 5th and 6th WHO international reference standards to the USDA veterinary reference standard.

    PubMed

    Hermann, J; Fry, A; Reising, M; Patterson, P; Siev, D; Gatewood, D

    2012-11-06

    Ensuring rabies vaccines are potent and effective is paramount in preventing transmission of this deadly disease and safeguarding public health. Efficacy of human and veterinary vaccines is ensured by evaluating relative potency estimates of the vaccine compared to a rabies reference standard using the National Institutes of Health (NIH) test. Reference vaccines are based on the International Standard for Rabies Vaccine provided by the World Health Organization (WHO). A comparison study was conducted to determine the relative potency of the 5th WHO, 6th WHO, and United States Department of Agriculture's (USDA) 08-14 reference standards using the NIH test. Results from the study demonstrate that the 6th WHO reference standard is approximately twice as potent as the 5th WHO reference when reconstituted to contain 1 IU per ml. Based on these results, the Center for Veterinary Biologics (CVB) doubled the reconstitution volume of USDA veterinary reference 08-14 from 13 ml to 26 ml, for an initial use dilution of 0.7 IU per ml for use by veterinary biologics manufacturers in the NIH test. This study emphasizes the importance of reference standard calibration for use in the National Institutes of Health test.

  3. New archeointensity data from French Early Medieval pottery production (6th-10th century AD). Tracing 1500 years of geomagnetic field intensity variations in Western Europe

    NASA Astrophysics Data System (ADS)

    Genevey, Agnès; Gallet, Yves; Jesset, Sébastien; Thébault, Erwan; Bouillon, Jérôme; Lefèvre, Annie; Le Goff, Maxime

    2016-08-01

    Nineteen new archeointensity results were obtained from the analysis of groups of French pottery fragments dated to the Early Middle Ages (6th to 10th centuries AD). They are from several medieval ceramic production sites, excavated mainly in Saran (Central France), and their precise dating was established based on typo-chronological characteristics. Intensity measurements were performed using the Triaxe protocol, which takes into account the effects on the intensity determinations of both thermoremanent magnetization anisotropy and cooling rate. Intensity analyses were also carried out on modern pottery produced at Saran during an experimental firing. The results show very good agreement with the geomagnetic field intensity directly measured inside and around the kiln, thus reasserting the reliability of the Triaxe protocol and the relevance of the quality criteria used. They further demonstrate the potential of the Saran pottery production for archeomagnetism. The new archeointensity results allow a precise and coherent description of the geomagnetic field intensity variations in Western Europe during the Early Medieval period, which was until now poorly documented. They show a significant increase in intensity during the 6th century AD, high intensity values from the 7th to the 9th century, with a minimum of small amplitude at the transition between the 7th and the 8th centuries and finally an important decrease until the beginning of the 11th century. Together with published intensity results available within a radius of 700 km around Paris, the new data were used to compute a master curve of the Western European geomagnetic intensity variations over the past 1500 years. This curve clearly exhibits five intensity maxima: at the transition between the 6th and 7th century AD, at the middle of the 9th century, during the 12th century, in the second part of the 14th century and at the very beginning of the 17th century AD. Some of these peaks are smoothed, or

  4. Comparison of Values in 5th, 6th, 7th and 8th Grade Primary Education Music Class Students'? Workbooks According to Rokeach?s and Akbas's Value Classifications

    ERIC Educational Resources Information Center

    Çakirer, H. Serdar

    2014-01-01

    The aim of the present study is to compare the values in the songs of 5th, 6th, 7th and 8th grade primary education music classes students? workbooks according to the value categorizations proposed by Rockeach and Akbas and which values among the categories mentioned are taught to the students in the 5th, 6th, 7th and 8th grade primary education…

  5. Construction of genome-wide physical BAC contigs using mapped cDNA as probes: Toward an integrated BAC library resource for genome sequencing and analysis. Annual report, July 1995--January 1997

    SciTech Connect

    Mitchell, S.C.; Bocskai, D.; Cao, Y.

    1997-12-31

    The goal of human genome project is to characterize and sequence entire genomes of human and several model organisms, thus providing complete sets of information on the entire structure of transcribed, regulatory and other functional regions for these organisms. In the past years, a number of useful genetic and physical markers on human and mouse genomes have been made available along with the advent of BAC library resources for these organisms. The advances in technology and resource development made it feasible to efficiently construct genome-wide physical BAC contigs for human and other genomes. Currently, over 30,000 mapped STSs and 27,000 mapped Unigenes are available for human genome mapping. ESTs and cDNAs are excellent resources for building contig maps for two reasons. Firstly, they exist in two alternative forms--as both sequence information for PCR primer pairs, and cDoreen genomic libraries efficiently for large number of DNA probes by combining over 100 cDNA probes in each hybridization. Second, the linkage and order of genes are rather conserved among human, mouse and other model organisms. Therefore, gene markers have advantages over random anonymous STSs in building maps for comparative genomic studies.

  6. Climate Change and the Water Cycle: A New Southwest Regional Climate Hub Curriculum Unit for 6th-12th Grade Students

    NASA Astrophysics Data System (ADS)

    Elias, E.; Steele, C. M.; Bestelmeyer, S.; Haan-Amato, S.; Deswood, H.; Rango, A.; Havstad, K.

    2015-12-01

    As climate change intensifies, increased temperatures and altered precipitation will make water, a limited resource in the arid southwestern United States, even scarcer in many locations. The USDA Southwest Regional Climate Hub (SWRCH) developed Climate Change and the Water Cycle, an engaging and scientifically rigorous education unit for 6th -12th grade students. The unit is aligned with Common Core State Standards and Next Generation Science Standards. Nine activities can be conducted over 10 instruction hours. Each activity can also stand alone. In partnership with SWRCH, the Asombro Institute for Science Education developed the unit. Each activity was reviewed by an educator for educational practices and by a scientist for scientific accuracy. The unit was pilot tested with 524 students in 2014, and pre- and post-tests were administered. Ninety-one percent of students were able to name a greenhouse gas on the post-test, compared to only 48% on the pre-test. On the post-test, 86% of students identified the relationship between average global temperature and carbon dioxide levels in the atmosphere, compared to only 52% on the pre-test. A student commented: "I loved all of the activities! They are fun and help us understand about what goes on in the world." Educators who participated in pilot testing said: "the entire curriculum is great, but I was particularly impressed with the progression of ideas and the variety of lessons," and "students could see the relevance and importance of these real life issues." Anyone interested in using the unit to host workshops for teachers in southwestern states should contact Asombro for more information (information@asombro.org). The Climate Change and the Water Cycle 6th-12th grade curriculum unit is available online: www.swclimatehub.info/education/climate-change-and-water-cycle

  7. Finished Prokaryotic Genome Assemblies from a Low-cost Combination of Short and Long Reads (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema

    Yin, Shuangye (Broad Institute)

    2016-07-12

    Shuangye Yin on "Finished prokaryotic genome assemblies from a low-cost combination of short and long reads" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  8. Finished Prokaryotic Genome Assemblies from a Low-cost Combination of Short and Long Reads (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect

    Yin, Shuangye

    2012-06-01

    Shuangye Yin on "Finished prokaryotic genome assemblies from a low-cost combination of short and long reads" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

  9. The 6th FDR prize

    NASA Astrophysics Data System (ADS)

    Funakoshi, Mitsuaki

    2013-06-01

    From the 58 papers published in 2012 in Fluid Dynamics Research, the following paper has been selected for the sixth FDR prize: The finite-difference lattice Boltzmann method and its application in computational aero-acoustics by Michihisa Tsutahara (Professor Emeritus, Kobe University, Japan), published in volume 44 (August 2012) 045507. This is a review paper of the author's recent work on the finite-difference lattice Boltzmann method (FDLBM). In this paper, the author introduces a modified FDLBM and its application to aero-acoustics. To solve the discrete Bhatnager, Gross and Krook equation for simulating fluid flow, the FDLBM applies a stable finite-difference scheme on a curvilinear coordinate system, whereas the ordinary lattice Boltzmann method uses regular lattices. It is known that for the lattice Boltzmann methods, there is difficulty in simulating high Mach number compressible flows in principle. To alleviate this, the author proposed the modified FDLBM, expanding the flexibility of setting time increments. With this FDLBM, the author has shown that it is possible to simulate compressible flows efficiently around complex bluff bodies and with complex aero-acoustic behaviour. The author summarizes all those works, including studies only available in Japanese up to now, in this review paper. After discussing the details of the FDLBM proposed by the author, example results of simulating the Aeolian tone generated from a circular cylinder at the Mach number M = 0.7 are shown. Then, the scheme is expanded for moving bodies by combining with the Arbitrary Lagrangian Eulerian formulation. Using this moving mesh scheme, the author shows the simulation results of the very strong sound pressure generated by a high-speed train in a tunnel. For issues of sound propagation in compressible two-phase flows whose density ratio is high, the two-particle model is introduced. Also, techniques to reduce noise generation from the flow velocity and pressure at gas-liquid interfaces are shown. Finally, the scattering of sound waves by water droplets is discussed. In thick fog, the sound coming from a distance becomes faint due to the sound-scattering effects of micro water droplets. The author gives an example of successfully solving such an issue by the FDLBM. It is highly admirable that the author developed the new FDLBM for aero-acoustic issues and has summarized it with sub-schemes to overcome several difficulties of engineering aeroacoustics in this review. It will certainly contribute to further development of fluid dynamics through computational aero-acoustics. Consequently, this paper was selected as the winner of the sixth FDR prize.

  10. NATO/CCMS PILOT STUDY CLEAN PRODUCTS AND PROCESSES (PHASE II) 2003 ANNUAL REPORT

    EPA Science Inventory

    The 6th annual meeting of the NATO CCMS Pilot Study, Clean Products and Processes, was held in Cetraro, Italy, from May 11 to 15, 2003. This was also the first meeting of its Phase II study. 24 country representatives attended this meeting. This meeting was very ably run by th...

  11. PanFunPro: Bacterial Pan-Genome Analysis Based on the Functional Profiles (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    SciTech Connect

    Lukjancenko, Oksana

    2012-06-01

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  12. PanFunPro: Bacterial Pan-Genome Analysis Based on the Functional Profiles (Seventh Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting 2012)

    ScienceCinema

    Lukjancenko, Oksana [Technical University of Denmark

    2016-07-12

    Julien Tremblay from DOE JGI presents "Evaluation of Multiplexed 16S rRNA Microbial Population Surveys Using Illumina MiSeq Platorm" at the 7th Annual Sequencing, Finishing, Analysis in the Future (SFAF) Meeting held in June, 2012 in Santa Fe, NM.

  13. Evidence of strong Quaternary earthquakes in the epicentral areaof the April 6th 2009 L'Aquila seismic event from sediment paleofluidization and overconsolidation

    NASA Astrophysics Data System (ADS)

    Storti, F.; Balsamo, F.; Aldega, L.; Corrado, S.; Di Paolo, L.; Mastalertz, M.; Tallini, M.

    2012-04-01

    The strong seismological potential of the Central Apennines, including the L'Aquila basin, is documented in the historical heritage of the past two millenia and by paleoseismological data. Despite the main active fault system network of Central Italy is well described and mapped, the April 6th 2009 L'Aquila event showed that Mw> 6.0 earthquakes can occur on fault zones characterized by subtlemorphotectonic evidence, like the Paganica Fault, whose seismic hazard potential may thus be overlooked. An additional source of uncertainty is provided by the evidence that in the L'Aquila region many active extensional fault systems developed by negative inversion of pre-existing contractional deformation structures. The resulting complex along-strike segmentation and overlap patterns are thus governed by the interplay between the modern extensional stress field and the structural inheritance and reduce the effectiveness of predictive scaling laws, which do not typically account for fault attributes produced by polyphased tectonics. This is particularly true in the L'Aquila region, where seismic activation of the northwestern half of the basin-boundary fault system has been proposed for the 1703 Mw ~ 7.0 earthquake, whereas only the central segment was activated in 1461 and 2009, producing earthquakes with Mw ~ 6.0 - 6.3. The reasons for this dual behaviour are still unclear despite many structural and paleoseismological studies. Indirect evidence for paleoearthquake magnitude from ground shaking effects, like paleo-fluidization structures, can provide very useful complementary information on maximum expected earthquake intensities along active fault systems.In this work wedescribe in detail large paleo-fluidization-induced features associated with a previously unmapped extensional fault zone cutting through Quaternary strata. These sediments, including lacustrine lignites and mudstones, show a somehow enigmatic overconsolidation that we quantitatively describe, as well as

  14. The Hetu'u Global Network: Using the rare June 5th/6th Transit of Venus to Bring Astronomy to the Remote Easter Island

    NASA Astrophysics Data System (ADS)

    Faherty, Jacqueline; Rodriguez, D.

    2013-01-01

    There are rare times in astronomy when a celestial event, visible in broad daylight, can be used to measure a fundamental parameter and inspire a globe full of school age students. The June 5th/6th transit of Venus was one such event. In celebration, nine astronomy postdocs from the Chilean mainland traveled to Easter Island to lead a series of astronomy outreach activities over three days, culminating in a transit-viewing event. Our team dubbed "Equipo Hetu'u" or "Team Star" in the Rapa Nui (Easter Island native) language spent two days giving astronomy talks and doing hands-on demonstrations at the Museo Antropologico P. Sebastian Englert. In the final day-and-a-half leading up to the transit, we visited the science classes in the majority of the schools on the island, in order to spread the message about the once-in-a-lifetime transit event, highlighting how we planned on using it to measure the distance to the Sun. We estimate over 25% 1500 people) of this remote island participated in one or more of our organized activities. Our experience with this project is an excellent lesson on how to organize, lead, and fully execute a major outreach endeavor that inspires hundreds with minimal resources (save the spectacular event provided by the cosmos).

  15. The Beginning of Metallurgy in the Southern Levant: A Late 6th Millennium CalBC Copper Awl from Tel Tsaf, Israel

    PubMed Central

    Garfinkel, Yosef; Klimscha, Florian; Shalev, Sariel; Rosenberg, Danny

    2014-01-01

    The beginning of metallurgy in the ancient Near East attracts much attention. The southern Levant, with the rich assemblage of copper artifacts from the Nahal Mishmar cave and the unique gold rings of the Nahal Qanah cave, is regarded as a main center of early metallurgy during the second half of the 5th millennium CalBC. However, a recently discovered copper awl from a Middle Chalcolithic burial at Tel Tsaf, Jordan Valley, Israel, suggests that cast metal technology was introduced to the region as early as the late 6th millennium CalBC. This paper examines the chemical composition of this item and reviews its context. The results indicate that it was exported from a distant source, probably in the Caucasus, and that the location where it was found is indicative of the social status of the buried individual. This rare finding indicates that metallurgy was first defused to the southern Levant through exchange networks and only centuries later involved local production. This copper awl, the earliest metal artifact found in the southern Levant, indicates that the elaborate Late Chalcolithic metallurgy developed from a more ancient tradition. PMID:24671185

  16. The beginning of metallurgy in the southern Levant: a late 6th millennium CalBC copper awl from Tel Tsaf, Israel.

    PubMed

    Garfinkel, Yosef; Klimscha, Florian; Shalev, Sariel; Rosenberg, Danny

    2014-01-01

    The beginning of metallurgy in the ancient Near East attracts much attention. The southern Levant, with the rich assemblage of copper artifacts from the Nahal Mishmar cave and the unique gold rings of the Nahal Qanah cave, is regarded as a main center of early metallurgy during the second half of the 5th millennium CalBC. However, a recently discovered copper awl from a Middle Chalcolithic burial at Tel Tsaf, Jordan Valley, Israel, suggests that cast metal technology was introduced to the region as early as the late 6th millennium CalBC. This paper examines the chemical composition of this item and reviews its context. The results indicate that it was exported from a distant source, probably in the Caucasus, and that the location where it was found is indicative of the social status of the buried individual. This rare finding indicates that metallurgy was first diffused [corrected] to the southern Levant through exchange networks and only centuries later involved local productionThis copper awl, the earliest metal artifact found in the southern Levant, indicates that the elaborate Late Chalcolithic metallurgy developed from a more ancient tradition.

  17. Modeling of local 3D effects of the April 6th 2009 l’Aquila (Italy) event in the City of Rome

    NASA Astrophysics Data System (ADS)

    Caserta, A.; Oprsal, I.; Rovelli, A.; Marra, F.; Govoni, A.; Vinci, S.

    2009-12-01

    Several events of the seismic sequence started on 6th of April 2009, that struck the town of l'Aquila, Italy, have been recorded by an array of seismic stations, located approximately 90 km south-west of the epicenters. One of the stations is in a 80-m-deep borehole, installed since the early 2008 in the middle of the main sedimentary body of the city: the Tiber valley. This represents a unique opportunity to tune seismic simulations of the soil shaking due to a seismic sequence located in Central Apennines region. This latter is considered, with the Albani Hills one, the main seismogenic area responsible of the seismic hazard in the city. We have generated a 3D velocity model for a portion of the city (5 EW x 3 NS km2 wide, and 200 m deep, including topography) where the array is located. A viscoelastic wave propagation due to S-wave pulse of general polarization and given incidence is obtained by the 3D FD hybrid numerical modeling. The 3D pulse response and the borehole recording are then used to generate the complete 3D synthetics covering the area. The results are verified by comparing to the surface recordings and large ground motion amplifications data.

  18. Vegetation dieback as a proxy for temperature within a wet pyroclastic density current: A novel experiment and observations from the 6th of August 2012 Tongariro eruption

    NASA Astrophysics Data System (ADS)

    Efford, Jackson T.; Bylsma, Rebecca J.; Clarkson, Bruce D.; Pittari, Adrian; Mauriohooho, Kate; Moon, Vicki G.

    2014-10-01

    The 6th of August 2012 eruption of Te Maari (Mt Tongariro, New Zealand) generated wet pyroclastic density currents (PDCs) which caused widespread dieback of vegetation (singed, brown foliage) in their path. An absence of significant charcoal formation suggests that PDC temperatures were mostly below 250 °C. Textural evidence for liquid water being present in the matrices during emplacement (vesicles) suggests that temperatures were < 100 °C. We determined a probable minimum PDC temperature using an experiment replicating the critical temperatures required to induce foliar browning in seven species affected by the eruption. In locations where all species exhibited browned foliage (or were defoliated), temperatures were probably ≥ 64 °C assuming a PDC duration of 60 s. In the more distal areas, where only the most susceptible species were browned while others remained healthy and unaffected, temperatures were probably around 51-58 °C. These results have relevance to volcanic hazard mitigation and risk assessment, especially on the popular Tongariro Alpine Crossing.

  19. Partnering to change the world for people with haemophilia: 6(th) Haemophilia Global Summit, Prague, Czech Republic, 24-26(th) September 2015.

    PubMed

    Astermark, Jan; Hart, Dan; Lobet, Sébastien; Blatný, Jan; d'Oiron, Roseline; Kenet, Gili; Dolan, Gerry; Libotte, Valérie; Hermans, Cedric

    2016-07-01

    The 6(th) Haemophilia Global Summit was held in Prague, Czech Republic, in September 2015. The programme was designed by an independent Scientific Steering Committee of haemophilia experts and aimed to share optimal management strategies for haemophilia at all life stages, explore recent potential advances in the management of haemophilia A and B and discuss challenges in haemophilia care. In this supplement from the meeting, Dan Hart reviews the lessons that can be learnt from cost-constrained environments with regard to improving care for people with haemophilia globally. Sébastien Lobet discusses the importance of physical activity for optimising care and Roseline d'Oiron and Jan Blatný consider the role of real-world data in understanding the effect of treatment in a clinical setting over the long term and the true impact of treatment on the day-to-day life of the patient. Gili Kenet addresses the current challenges relating to the optimal management of prophylaxis, and Gerry Dolan and Cedric Hermans discuss the value of pharmacokinetic (PK) parameters in informing treatment decisions. Cedric Hermans and Valérie Libotte explore the importance of considering social and occupational development factors as an integral part of haemophilia care, and Jan Astermark reviews key strategies to predict and prevent inhibitor development.

  20. The 6th Meeting of the Global Alliance to Eliminate Lymphatic Filariasis: A half-time review of lymphatic filariasis elimination and its integration with the control of other neglected tropical diseases

    PubMed Central

    2010-01-01

    The 6th Meeting of the Global Alliance to Eliminate Lymphatic Filariasis (GAELF6) was held 1-3 June, 2010 in Seoul, Korea, with 150 participants from 38 countries. The year 2010 marks the midpoint between the first GAELF meeting, in 2000, and the World Health Organization (WHO) 2020 goal of global elimination of lymphatic filariasis (LF) as a public health problem. The theme of the meeting, "Half-time in LF Elimination: Teaming Up with Neglected Tropical Diseases (NTDs)," reflected significant integration of LF elimination programmes into a comprehensive initiative to control NTDs. Presentations on LF epidemiology, treatment, research, and programmes highlighted both accomplishments and remaining challenges. The WHO strategy to interrupt LF transmission is based on annual mass drug administration (MDA) using two-drug combinations. After mapping the geographic distribution of LF, MDA is implemented for ≥ 5 years, followed by a period of post-MDA surveillance, and, ultimately, verification of LF elimination. Morbidity management further reduces disease burden. Of 81 countries considered LF-endemic in 2000, 52 (64.2%) have begun MDA; 10 (12.3%) others with low-level transmission are unlikely to require MDA. In 2008, ~695 million people were offered treatment (51.7% of the at-risk population); ~496 million participated. Approximately 22 million people have been protected from LF infection and disease, with savings of ~US $24.2 billion. Morbidity management programmes have been implemented in 27 (33.3%) countries. Significant challenges to LF elimination remain. These include: initiating MDA in the remaining 19 countries that require it; achieving full geographic coverage in countries where MDA has started; finding alternative strategies to address the problem of Loa loa co-endemicity in Central Africa; developing strategies to treat urban populations; initiating and sustaining MDA in settings of armed conflict; developing refined guidelines and procedures for

  1. Process evaluation for a school-based physical activity intervention for 6th- and 7th-grade boys: reach, dose, and fidelity.

    PubMed

    Robbins, Lorraine B; Pfeiffer, Karin Allor; Wesolek, Stacey M; Lo, Yun-Jia

    2014-02-01

    The purpose was to evaluate the reach, dose, and fidelity of Guys Only Activity for Life (G.O.A.L.), a 7-week pilot intervention conducted from February to March 2011 to increase 6th and 7th grade boys' moderate-to-vigorous physical activity (MVPA). One middle school was randomly assigned to the G.O.A.L. intervention and another from the same urban school district in the Midwestern U.S. to a comparison condition. Thirty boys, ages 10-14 years, participated in each school. The intervention, guided by the Health Promotion Model (HPM) and Self-Determination Theory (SDT), consisted of a 90-min after-school physical activity club 4 days/week and one motivational interviewing session with a registered (school) nurse. Data were gathered via attendance records, club observations, heart rate monitors, audio-taping of motivational interviewing sessions, and surveys. On average boys attended the club 2.11 days/week (SD=.86). A trained independent process evaluator reported that the physical activity club instructors provided the boys with the opportunity for a mean of 25.8 min/day of MVPA. Using a four-point Likert scale (1=disagree a lot; 4=agree a lot), the process evaluator perceived that the club was delivered with high fidelity and adherence to the underlying theories (M=3.48; SD=0.39). Sessions with the nurse lasted an average of 13 min, 29 s. All boys attended. Two trained independent coders indicated that the nurse demonstrated at least beginning proficiency for all tasks associated with motivational interviewing, with the exception of using sufficient open- as opposed to closed-ended questions and reflections compared to questions. Fidelity related to session delivery and adherence to the theories was high (M=3.83; SD=0.19). The process evaluation data indicated that strategies are needed to increase attendance and boys' MVPA during the club time.

  2. Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT).

    PubMed

    Speit, Günter; Kojima, Hajime; Burlinson, Brian; Collins, Andrew R; Kasper, Peter; Plappert-Helbig, Ulla; Uno, Yoshifumi; Vasquez, Marie; Beevers, Carol; De Boeck, Marlies; Escobar, Patricia A; Kitamoto, Sachiko; Pant, Kamala; Pfuhler, Stefan; Tanaka, Jin; Levy, Dan D

    2015-05-01

    As a part of the 6th IWGT, an expert working group on the comet assay evaluated critical topics related to the use of the in vivo comet assay in regulatory genotoxicity testing. The areas covered were: identification of the domain of applicability and regulatory acceptance, identification of critical parameters of the protocol and attempts to standardize the assay, experience with combination and integration with other in vivo studies, demonstration of laboratory proficiency, sensitivity and power of the protocol used, use of different tissues, freezing of samples, and choice of appropriate measures of cytotoxicity. The standard protocol detects various types of DNA lesions but it does not detect all types of DNA damage. Modifications of the standard protocol may be used to detect additional types of specific DNA damage (e.g., cross-links, bulky adducts, oxidized bases). In addition, the working group identified critical parameters that should be carefully controlled and described in detail in every published study protocol. In vivo comet assay results are more reliable if they were obtained in laboratories that have demonstrated proficiency. This includes demonstration of adequate response to vehicle controls and an adequate response to a positive control for each tissue being examined. There was a general agreement that freezing of samples is an option but more data are needed in order to establish generally accepted protocols. With regard to tissue toxicity, the working group concluded that cytotoxicity could be a confounder of comet results. It is recommended to look at multiple parameters such as histopathological observations, organ-specific clinical chemistry as well as indicators of tissue inflammation to decide whether compound-specific toxicity might influence the result. The expert working group concluded that the alkaline in vivo comet assay is a mature test for the evaluation of genotoxicity and can be recommended to regulatory agencies for use.

  3. Study of the Effects on Student Knowledge and Perceptions of Activities Related to Submetering the 6th Grade Wing of a Middle School, to Displaying the Carbon Footprint, and to Efforts to Reduce Energy Consumption and Greenhouse Gases

    ERIC Educational Resources Information Center

    Peck, Rick

    2009-01-01

    The purpose of the study was to determine the effects upon student knowledge and perceptions regarding greenhouse gas emissions as a result of an intervention relying upon the submetering the 6th grade wing of a Middle School, displaying the information regarding electrical consumption and carbon footprint, and reducing the electrical consumption…

  4. How Do 4th, 5th, and 6th Grade Students' Categories of Cognitive Reflections in Interviews on Derivational Morphology Compare to Their Upper Level Spelling Inventory Orthographic Knowledge?

    ERIC Educational Resources Information Center

    Smith, Darcie D.

    2012-01-01

    Eighty-seven 4th, 5th and 6th grade students were administered the "Derivational Relatedness Interview" (DRI) (Templeton, Smith, Moloney, Van Pelt, & Ives, 2009). The purpose of this instrument is to explore students' understanding of derivational morphology. During the same week, the subjects were also administered an Upper…

  5. EDITORIAL: The 6th International Workshop on Micro and Nanotechnologies for Power Generation and Energy Conversion Applications (PowerMEMS 2006)

    NASA Astrophysics Data System (ADS)

    Fréchette, Luc G.

    2007-09-01

    Energy is a sector of paramount importance over the coming decades if we are to ensure sustainable development that respects our environment. The research and development of novel approaches to convert available energy into usable forms using micro and nanotechnologies can contribute towards this goal and meet the growing need for power in small scale portable applications. The dominant power sources for handheld and other portable electronics are currently primary and rechargeable batteries. Their limited energy density and adverse effects on the environment upon disposal suggest that alternative approaches need to be explored. This special issue will showcase some of the leading work in this area, initially presented at PowerMEMS 2006, the 6th International Workshop on Micro and Nanotechnologies for Power Generation and Energy Conversion Applications. Power MEMS are defined as microsystems for electrical power generation and other energy conversion applications, including propulsion and cooling. The range of power MEMS technologies includes micro thermodynamic machines, such as microturbines, miniature internal combustion engines and micro-coolers; solid-state direct energy conversion, such as thermoelectric and photovoltaic microstructures; micro electrochemical devices, such as micro fuel cells and nanostructure batteries; vibration energy harvesting devices, such as piezoelectric, magnetic or electrostatic micro generators, as well as micro thrusters and rocket engines for propulsion. These can either be driven by scavenging thermal, mechanical or solar energy from the environment, or from a stored energy source, such as chemical fuel or radioactive material. The unique scope leads to unique challenges in the development of power MEMS, ranging from the integration of novel materials to the efficient small scale implementation of energy conversion principles. In this special issue, Mitcheson et al provide a comparative assessment of three inertial vibration

  6. Emergency Preparedness and Management at the University of L’aquila (Central Italy) and the Role of Students’ Associations in the April 6th 2009 Earthquake

    PubMed Central

    Magni, Michele; Fraboni, Rita; Marincioni, Fausto

    2017-01-01

    Introduction: On April 6th 2009 an earthquake of Mw=6.3 hit the historical downtown of L’Aquila and its hinterland causing more than 300 fatalities and severe damage to private and public buildings. At the time, the University of L’Aquila represented a major source of employment and income for the city. The earthquake impacted both the facilities and the administrative, financial and patrimonial activities of the university, bringing into the open the tendency – widespread in Italy – to rely on adaptive tactics rather than on strategic pre-disaster plans. This paper investigates the university’s emergency preparedness and response capability and  the strategies adopted to restore the education activities as well as avoid students migration to other universities. In addition, emphasis is placed on the role played by Student Associations in pre and post-disaster phases, and how students perceived the activities performed by these associations. Methods: To achieve this goal, it was undertaken: i) qualitative evaluation to assess the impact of earthquake on services and facilities of the university, the emergency preparedness and the measures adopted to face the emergency, ii) survey on the role played by Student Associations, both in emergency preparedness and response, according to students’ perception; iii) quantitative analysis to measure changes in the enrollment trend after the earthquake, and how university policies could curb students’ migration. Results: The policies adopted by the University allowed to diminish students’ migration; however, the measures taken by the university were based on an ad hoc plan as no emergency and continuity plans were prepared in advance. Similarly Student Associations got involved more in restoration activities than in emergency preparedness and risk awareness promotion. Discussion: Greater awareness and involvement are essential at each level (administrators, faculties, students) to plan in advance for an

  7. Comparative studies on the structure of human adenovirus genomes 4, 7 and 21. Annual progress report 1 Feb 80-2 Feb 81

    SciTech Connect

    Padmanabhan, R.

    1980-02-01

    A sensitive method was developed to label the 5' termini of Ad DNA which was found to be applicable to Ad 7, Ad 4 and Ad 21 DNA due to the presence of a tyrosine-containing peptide covalently attached to these DNA molecules. Ad 7 vaccine strain was passaged in 293 cells and then grown in large amounts in suspension cultures of KB cells. The DNA was extracted and purified. Restriction enzyme analysis of vaccine and Greider Ad 7 strains revealed that the two strains gave identical cleavage patterns with 8 restriction enzymes. Ad 4 prototype strain (ATCC) have been passaged in 293 cells and then grown in large amounts in suspension cultures of human KB cells. The DNA from these virions have been extracted and purified. Ad 21 vaccine strain has been passaged in 293 cells and then the virus was grown in KB cell suspension cultures. We are currently in the process of isolating the DNA and analyzing its genomic organization with several restriction enzymes. We analyzed the efficiencies of different protocols for titering the live Ad vaccine strains Ad 4, Ad 7 and Ad 21 present in enteric coated tablets.

  8. Industrial College of the Armed Forces and Mobilization Concepts Development Center Annual Mobilization Conference Proceedings (6th) Held 16-17 April 1987: Marshaling Resources for Conflict Short of Declared War; Do We have a Process.

    DTIC Science & Technology

    1987-04-17

    women . . %% % N- You look at it and logically you say, "This would be a good thing to do because if we go to war we really ought to know who the...to deal with this, the story comes out, "Pentagon getting ready to draft women ." We don’t even register women . We have a President who feels about the...discussing this idea about registering women medical professionals because lots of women are medical professionals, very good ones. The next thing you know

  9. Images in Transition. Proceedings of the Annual Society for the Advancement of Gifted Education (SAGE) Conference (3rd, Calgary, Alberta, Canada, September 24-26, 1992) and the Canadian Symposium on Gifted Education (6th).

    ERIC Educational Resources Information Center

    Calgary Univ. (Alberta). Centre for Gifted Education.

    This document presents the conference proceedings of the primary stakeholders in gifted education in Alberta (Canada): "Activities in Math for the Gifted Student" (Ballheim); "The Self Awareness Growth Experiences Approach" (Balogun); "Computer Simulations: An Integrating Tool" (Bilan); "The Portrayal of Gifted…

  10. The Education Service: In or Out of Local Government? Proceedings of the Annual Conference of the British Educational Administration Society (6th, University of Birmingham, England, September 23-24, 1977).

    ERIC Educational Resources Information Center

    Lambert, Kenneth, Ed.

    This conference focused on the present position of British education within local government and whether schools can function effectively under local control. Issues discussed included the question of whether the schools were providing industry with employees having appropriate academic ability and social skills, the question of whether…

  11. The Korean Language in America: Volume 6. Papers from the Annual Conference and Teacher Training Workshop on the Teaching of Korean Language, Culture, and Literature (6th, Manoa, Hawaii, August 2-5, 2001).

    ERIC Educational Resources Information Center

    Ree, Joe Jungno, Ed.

    This collection of conference papers includes: (1) "Theories, Evidence, and Practice in Foreign Language Teaching" (Richard Schmidt); (2) "Teaching Korean Grammar in Context: -myen and -ttay" (Sahie Kang); (3) "Teaching Politeness Routines in Korean" (Ho-min Sohn); (4) "Vocabulary-Building Activities"…

  12. From Great Potential to Amazing Performance: Factors That Make a Difference. Abstracts of Selected Papers [from the] Annual Esther Katz Rosen Symposium on the Psychological Development of Gifted Children (6th, Lawrence, Kansas, September 20-21, 1996).

    ERIC Educational Resources Information Center

    Kansas Univ., Lawrence.

    Twenty-two abstracts of papers presented at a symposium on the psychological development of gifted children comprise this document. Abstracts typically include the title of the paper; the author's name, title, institutional affiliation, location, telephone number, and electronic mail address; and a summary of the paper ranging from a short…

  13. PIALA '96. Jaketo Jaketak Kobban Alele Eo--Identifying, Using and Sharing Local Resources. Proceedings of the Annual Pacific Islands Association of Libraries and Archives Conference (6th, Majuro, Marshall Islands, November 5-8, 1996).

    ERIC Educational Resources Information Center

    Cohen, Arlene, Ed.

    This 1996 PIALA conference explores ways to identify and make available local resources on the Marshall Islands. The traditional Marshallese word, "Alele," which means "the basket which holds the tools, treasures and resources needed for everyday life," is also the name of Majuro's public library, museum and Marshall Islands…

  14. Methodology of evaluation of morphology of the spine and the trunk in idiopathic scoliosis and other spinal deformities - 6th SOSORT consensus paper

    PubMed Central

    2009-01-01

    Background Comprehensive evaluation of the morphology of the spine and of the whole body is essential in order to correctly manage patients suffering from progressive idiopathic scoliosis. Although methodology of clinical and radiological examination is well described in manuals of orthopaedics, there is deficit of data which clinical and radiological parameters are considered in everyday practise. Recently, an increasing tendency to extend scoliosis examination beyond the measure of the Cobb angle can be observed, reflecting a more patient-oriented approach. Such evaluation often involves surface parameters, aesthetics, function and quality of life. Aim of the study To investigate current recommendations of experts on methodology of evaluation of the patient with spinal deformity, essentially idiopathic scoliosis. Methods Structured Delphi procedure for collecting and processing knowledge from a group of experts with a series of questionnaires and controlled opinion feedback was performed. Experience and opinions of the professionals - physicians and physiotherapists managing scoliosis patients - were studied. According to Delphi method a Meeting Questionnaire (MQ) has been developed, resulting from a preliminary Pre-Meeting Questionnaire (PMQ) which had been previously discussed and approved on line. The MQ was circulated among the SOSORT experts during Consensus Session on "Measurements" which took place at the Annual Meeting of the Society, totally 23 panellists being engaged. Clinical, radiological and surface topography parameters were checked for agreement. Results 90% agreement or more was reached in 35 items and superior than 75% agreement was reached in further 25 items. An evaluation form was proposed to be used by clinicians and researchers. Conclusion The consensus was reached on evaluation of the morphology of the patient with idiopathic scoliosis, comprising clinical, radiological and, to less extend, surface topography assessment. Considering the

  15. PREFACE: MEM11: The 6th International Workshop on Mechanical-Electromagnetic Properties of Composite Superconductors (Okinawa, Japan, 5-7 December 2011) MEM11: The 6th International Workshop on Mechanical-Electromagnetic Properties of Composite Superconductors (Okinawa, Japan, 5-7 December 2011)

    NASA Astrophysics Data System (ADS)

    Awaji, Satoshi; Osamura, Kozo; Hampshire, Damian

    2012-05-01

    The effect of stress and strain on the electromagnetic properties of superconducting composite conductors is one of the key issues for the practical application of superconductivity. To discuss these subjects thoroughly, the International Workshop on Mechanical-Electromagnetic Properties of Composite Superconductors (MEM) has been held regularly since 2001. The 6th workshop (MEM11) was held in Okinawa, Japan in 2011, which was the centennial of the discovery of superconductivity by Professor Kamerlingh Onnes, as well as the 25th anniversary of the discovery of high temperature superconductors (HTS). Although it was originally planned that MEM11 be held in Mito, the workshop venue was changed because of the serious disaster in the north of Japan on 11 March 2011. Sixty five scientists participated in this specialized workshop. Fifty six papers were presented in the following six sessions: (1) Intrinsic strain effects on low temperature superconductors (LTS) and HTS, (2) The International Thermonuclear Experimental Reactor (ITER), (3) Strain evaluation by quantum beams, (4) Flux pinning properties of HTS, (5) Standardization and the Versailles Project on Advanced Materials and Standards (VAMAS) and (6) High field magnets. Several large topics were presented and discussed at the workshop: the important progress in methods for non-invasive measurements of the local strain exerted on the superconducting components in superconducting wires and cables using quantum beam techniques. This approach provides powerful tools for investigating the effect of strain in composite superconductors; the intrinsic strain effects in LTS and HTS in the reversible strain region. Recently, it has become easier to determine quantitatively the strain dependence of critical current when the local strain is measured directly, and the mechanical and electromagnetic properties of the superconductors used in the ITER tokamak. This was a major topic at the workshop since the superconducting

  16. EDITORIAL: Proceedings of the 6th Edoardo Amaldi Conference on Gravitational Waves, Bankoku Shinryoukan, Okinawa, Japan, 20-24 June 2005 Proceedings of the 6th Edoardo Amaldi Conference on Gravitational Waves, Bankoku Shinryoukan, Okinawa, Japan, 20-24 June 2005

    NASA Astrophysics Data System (ADS)

    Mio, N.

    2006-04-01

    This issue is published as the Proceedings of the 6th Edoardo Amaldi Conference on Gravitational Waves, held on 20-24 June 2005 at Bankoku Shinryoukan in Okinawa, Japan. Since the first Amaldi conference was held in Frascati in 1994, eleven years have passed and the scale of the conference has grown with the increasing activity in the field of gravitational waves. As the centenary celebration of Einstein's 'miracle year', 2005 was called 'World Year of Physics'. Among his breakthroughs published in 1905, the special theory of relativity is recognized as the most significant revolution in physics, completely changing our views concerning time and space. Ten years later, Einstein proposed the general theory of relativity, by which he predicted the existence of gravitational waves (GWs). At that time, it was only a dream to observe a GW because its effect was so small. Efforts to detect GWs, pioneered by Weber, have continued for almost 40 years, yet their detection remained a dream. However, the presentations at this conference have convinced us that it is no longer a dream. The GW detector projects have made extraordinary advances; in particular, the significant sensitivity improvement of LIGO and the completion of the VIRGO detector mark the beginning of the new era of GW physics. Firm developments in theories and source estimations were also reported. In particular, the data analysis session was very active and various discussions were held. Elaborate experimental techniques were presented, some of them already achieving the requirements for the next generation of detectors, such as Advanced LIGO and LCGT. In addition to the earth-based detectors, many presentations concerning space detectors were contributed; they indicated that space would become the new stage for GW physics and astronomy. This issue brings together the papers which were presented at this exciting conference. The proceedings comprise two volumes; the largest part is published as a volume of

  17. Building on Family Strengths: Research and Services in Support of Children and Their Families. Proceedings of the Building on Family Strengths Annual Conference (11th, Portland, Oregon, May 6-8, 2004)

    ERIC Educational Resources Information Center

    Gordon, Lynwood J., Ed.; Tullis, Kathryn, Ed.; Hanson, Andrea, Ed.; Sowders, Stacey, Ed.

    2005-01-01

    The 11th Annual Building on Family Strengths Conference was held from May 6th through May 8th, 2004, in Portland, Oregon. Highlights included: (1) The revival of a pre-conference training session; this year featured "Understanding Research and Evaluation in Relation to Social Change," presented by Elaine Slaton and Shannon CrossBear of…

  18. Threshold Concepts: From Personal Practice to Communities of Practice. Proceedings of the National Academy's Sixth Annual Conference and the Fourth Biennial Threshold Concepts Conference [E-publication] (Dublin, Ireland, June 27-29, 2012)

    ERIC Educational Resources Information Center

    O'Mahony, Catherine, Ed.; Buchanan, Avril, Ed.; O'Rourke, Mary, Ed.; Higgs, Bettie, Ed.

    2014-01-01

    The 6th Annual Conference of the National Academy for the Integration of Research, Teaching and Learning (NAIRTL) and the 4th Biennial Threshold Concepts Conference was held at Trinity College Dublin, Ireland, on June 27-29, 2012. The NAIRTL is a collaborative initiative between University College Cork, Cork Institute of Technology, National…

  19. 16th Annual Land O'Lakes Bioanalytical Conference.

    PubMed

    Burns, Erik C; Guthrie, Randall H; Fluhler, Eric N; Stubbs, R John; Bateman, Kevin; King, Lindsay; Moran, Jeffrey

    2015-11-01

    This Land O'Lakes Conference is presented each year by the Division of Pharmacy Professional Development within the School of Pharmacy at the University of Wisconsin-Madison (USA). The purpose of this 3-day conference is to provide an educational forum to discuss issues and applications associated with the analysis of xenobiotics, metabolites, biologics and biomarkers in biological matrices. The conference is designed to include and encourage an open exchange of scientific and methodological applications for bioanalysis. To increase the interactive nature of the conference, the program is a mixture of lectures, interactive discussions and a poster session. This report summarized the presentations at the 16th Annual Conference. 6th Annual Land O'Lakes Bioanalytical Conference, Fluno Center Madison, WI, USA, 13-16 July 2015.

  20. Discovering the Universe, 6th edition

    NASA Astrophysics Data System (ADS)

    Comins, Neil F.; Kaufmann, William J.

    Discovering the Universe is the best-selling brief text for descriptive one-term astronomy courses (especially those with no mathematics prerequisites). Carried along by the book's vibrant main theme--the process of scientific discovery--readers will encounter spectacular sights, landmark experiments, and recent discoveries, while learning to avoid the pitfalls created by common misconceptions about astronomy. Now enhanced with a powerful technology and image projection package, this is the most exciting and effective edition yet. The accompanying CD-ROM features a special student version of the award-winning virtual planetarium software, Starry Night? Backyard.

  1. Imagine the Universe! (6th Edition)

    NASA Technical Reports Server (NTRS)

    Lochner, James; White, Nicholas E. (Technical Monitor)

    2002-01-01

    Contained on this CD-ROM you will find three astronomy and space science learning centers, individually captured from the World Wide Web in December of 2001. Each site contains its own learning adventure full of facts, fun, beautiful images, movies, and excitement!

  2. Elementary Science Guide -- 6th Grade.

    ERIC Educational Resources Information Center

    Wieland, Anne; And Others

    Presented is a resource book to be used with instructional kits for elementary school science students, grade 6. The individual units at this grade level are based on curriculum which has been developed by the National Science Foundation in the 1960s and revised to meet student and teacher identified needs in Anchorage, Alaska. Six units are…

  3. European Conference on Visual Perception (6th).

    DTIC Science & Technology

    1983-11-30

    selected by an international committee of referees: Prof. Giovanni BERLUCCHI Istituto di Fisiologia umana Universitl di Pisa Via S. Zeno. 31 56100...CB2 3EG - Great Britain P. BAGNOLI: Istituto di Fisiologia , Universit& di Pisa, Via S. Zeno, 29-31 - 56100 Pisa, Italy J. BARBUR: Department of...Applied Psychology, University of UmeE, 901 87 Umet - Sweden G. BERLUCCHI: Istituto di Fisiologia , Universit di Pisa, Via S. Zeno, 29/31 -.56100 Pisa

  4. Shrinking genomes? Evidence from genome size variation in Crepis (Compositae).

    PubMed

    Enke, N; Fuchs, J; Gemeinholzer, B

    2011-01-01

    Large-scale surveys of genome size evolution in angiosperms show that the ancestral genome was most likely small, with a tendency towards an increase in DNA content during evolution. Due to polyploidisation and self-replicating DNA elements, angiosperm genomes were considered to have a 'one-way ticket to obesity' (Bennetzen & Kellogg 1997). New findings on how organisms can lose DNA challenged the hypotheses of unidirectional evolution of genome size. The present study is based on the classical work of Babcock (1947a) on karyotype evolution within Crepis and analyses karyotypic diversification within the genus in a phylogenetic context. Genome size of 21 Crepis species was estimated using flow cytometry. Additional data of 17 further species were taken from the literature. Within 30 diploid Crepis species there is a striking trend towards genome contraction. The direction of genome size evolution was analysed by reconstructing ancestral character states on a molecular phylogeny based on ITS sequence data. DNA content is correlated to distributional aspects as well as life form. Genome size is significantly higher in perennials than in annuals. Within sampled species, very small genomes are only present in Mediterranean or European species, whereas their Central and East Asian relatives have larger 1C values.

  5. Genome assortment, not serogroup, defines Vibrio cholerae pandemic strains

    SciTech Connect

    Brettin, Thomas S; Bruce, David C; Challacombe, Jean F; Detter, John C; Han, Cliff S; Munik, A C; Chertkov, Olga; Meincke, Linda; Saunders, Elizabeth; Choi, Seon Y; Haley, Bradd J; Taviani, Elisa; Jeon, Yoon - Seong; Kim, Dong Wook; Lee, Jae - Hak; Walters, Ronald A; Hug, Anwar; Colwell, Rita R

    2009-01-01

    Vibrio cholerae, the causative agent of cholera, is a bacterium autochthonous to the aquatic environment, and a serious public health threat. V. cholerae serogroup O1 is responsible for the previous two cholera pandemics, in which classical and El Tor biotypes were dominant in the 6th and the current 7th pandemics, respectively. Cholera researchers continually face newly emerging and re-emerging pathogenic clones carrying combinations of new serogroups as well as of phenotypic and genotypic properties. These genotype and phenotype changes have hampered control of the disease. Here we compare the complete genome sequences of 23 strains of V. cholerae isolated from a variety of sources and geographical locations over the past 98 years in an effort to elucidate the evolutionary mechanisms governing genetic diversity and genesis of new pathogenic clones. The genome-based phylogeny revealed 12 distinct V. cholerae phyletic lineages, of which one, designated the V. cholerae core genome (CG), comprises both O1 classical and EI Tor biotypes. All 7th pandemic clones share nearly identical gene content, i.e., the same genome backbone. The transition from 6th to 7th pandemic strains is defined here as a 'shift' between pathogenic clones belonging to the same O1 serogroup, but from significantly different phyletic lineages within the CG clade. In contrast, transition among clones during the present 7th pandemic period can be characterized as a 'drift' between clones, differentiated mainly by varying composition of laterally transferred genomic islands, resulting in emergence of variants, exemplified by V.cholerae serogroup O139 and V.cholerae O1 El Tor hybrid clones that produce cholera toxin of classical biotype. Based on the comprehensive comparative genomics presented in this study it is concluded that V. cholerae undergoes extensive genetic recombination via lateral gene transfer, and, therefore, genome assortment, not serogroup, should be used to define pathogenic V

  6. New Perspectives on Aging in the Post Genome Era. Program Abstracts. Annual Scientific Meeting of the Gerontological Society of America (52nd, San Francisco, California, November 19-23, 1999).

    ERIC Educational Resources Information Center

    Greene, Vernon L., Ed.

    1999-01-01

    This special issue of "The Gerontologist" contains session-by-session abstracts from the society's 52nd Annual Scientific Meeting. Abstracts are arranged numerically by session number and in the order of presentation within each session. There are a total of 375 sessions. An index of participants is provided with references to their…

  7. Ascaris suum draft genome.

    PubMed

    Jex, Aaron R; Liu, Shiping; Li, Bo; Young, Neil D; Hall, Ross S; Li, Yingrui; Yang, Linfeng; Zeng, Na; Xu, Xun; Xiong, Zijun; Chen, Fangyuan; Wu, Xuan; Zhang, Guojie; Fang, Xiaodong; Kang, Yi; Anderson, Garry A; Harris, Todd W; Campbell, Bronwyn E; Vlaminck, Johnny; Wang, Tao; Cantacessi, Cinzia; Schwarz, Erich M; Ranganathan, Shoba; Geldhof, Peter; Nejsum, Peter; Sternberg, Paul W; Yang, Huanming; Wang, Jun; Wang, Jian; Gasser, Robin B

    2011-10-26

    Parasitic diseases have a devastating, long-term impact on human health, welfare and food production worldwide. More than two billion people are infected with geohelminths, including the roundworms Ascaris (common roundworm), Necator and Ancylostoma (hookworms), and Trichuris (whipworm), mainly in developing or impoverished nations of Asia, Africa and Latin America. In humans, the diseases caused by these parasites result in about 135,000 deaths annually, with a global burden comparable with that of malaria or tuberculosis in disability-adjusted life years. Ascaris alone infects around 1.2 billion people and, in children, causes nutritional deficiency, impaired physical and cognitive development and, in severe cases, death. Ascaris also causes major production losses in pigs owing to reduced growth, failure to thrive and mortality. The Ascaris-swine model makes it possible to study the parasite, its relationship with the host, and ascariasis at the molecular level. To enable such molecular studies, we report the 273 megabase draft genome of Ascaris suum and compare it with other nematode genomes. This genome has low repeat content (4.4%) and encodes about 18,500 protein-coding genes. Notably, the A. suum secretome (about 750 molecules) is rich in peptidases linked to the penetration and degradation of host tissues, and an assemblage of molecules likely to modulate or evade host immune responses. This genome provides a comprehensive resource to the scientific community and underpins the development of new and urgently needed interventions (drugs, vaccines and diagnostic tests) against ascariasis and other nematodiases.

  8. Report on the 6th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 31th - Nov. 2nd, 2014.

    PubMed

    Kleinschnitz, Christoph; Linker, Ralf A; Magnus, Tim; Korn, Thomas; Meuth, Sven G

    2015-01-01

    From October 31th - November 2nd, 2014, the 6th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. 70 doctoral students and postdocs from over 25 different groups working in German and Swiss university hospitals or research institutes attended the meeting to discuss their latest experiments and findings in the fields of neuroimmunology, neurodegeneration and neurovascular research. The meeting was regarded as a very well organized platform to support research of young investigators in Germany and all participants enjoyed the stimulating environment for lively in depth discussions. According to the major aim of NEUROWIND e.V. to support younger researchers in Germany the 4th NEUROWIND YOUNG SCIENTIST AWARD for experimental neurology was awarded to Michael Breckwoldt on his work in the group of Thomas Misgeld (Institute of Neuronal Cell Biology, Technische Universität München, Germany). The successful project was published in Nature Medicine entitled "Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo". This outstanding paper deals with a molecular imaging approach in living mice to optically analyze the role of mitochondrial redox signals in axons in health and disease. The award is endowed with 20.000 Euro sponsored by Merck Serono GmbH, Darmstadt, Germany (unrestricted educational grant). This year's keynote lecture was given by Bernhard Hemmer, Head of the Department of Neurology at the Klinikum rechts der Isar, Technische Universität München. Dr. Hemmer highlighted the particular role of B cells and (auto)antibodies in multiple sclerosis (MS). As a new highlight Dr. Urbahns, head of global discovery technologies at Merck research laboratories, gave insights from research practice in the pharmaceutical industry and introduced a shift in the view on present-day drug discovery paradigms.

  9. Comparative Evaluation of Microshear Bond Strength of 5th, 6th and 7th Generation Bonding Agents to Coronal Dentin Versus Dentin at Floor of Pulp Chamber: An In vitro Study

    PubMed Central

    Deepa, Velagala Lakshmi; Damaraju, Bhargavi; Priyadharsini, Bollu Indira; Subbarao, Vummidisetti V; Raju, K Rama Krishna

    2014-01-01

    Background: Lack of seal and adhesion between the final restoration and tooth structure adversely affects the results of root canal treatment. Lots of adhesive bonding agents are marketed to overcome this deficiency and achieve successful restoration. So the study compares and evaluates the micro shear bond strength of coronal dentin and pulp chamber dentin using three different generation dentin bonding systems and to know clinical efficiency for clinical use. Materials and Methods: Different generation dentin bonding systems used were: (1) One bottle total etch system (XP Bond-5th generation), (2) Two-step self-etch system (Clearfil SE Bond-6th generation) and (3) All-in-one system (G Bond-7th generation). Thirty human mandibular molars were collected out of which sixty samples were prepared by sectioning each tooth into coronal dentin and pulpal floor dentin. They were divided into two major groups. Group I: 30 Coronal dentin samples. Group II:30 Pulpal floor dentin samples. Both the groups were further subdivided depending on the bonding agent used. Subgroup Ia:XP Bond, Subgroup Ib:Clearfil SE Bond, Subgroup Ic:G Bond, Subgroup IIa:XP Bond, Subgroup IIb:Clearfil SE Bond, Subgroup IIc:G Bond. Resin composite was bonded to these samples and tested for micro-shear bond strength. The mean bond strengths and standard deviations were calculated and analyzed using one-way ANOVA test and Student’s t-test (unpaired) and honestly significant difference post-hoc tests. Results: Coronal dentin showed higher values of micro shear bond strength than the pulpal floor dentin. All-in-one system (G Bond) showed least bond strength values to both the regions coronal dentin and pulpal floor dentin. Conclusion: Factors affecting the shear bond strength are dependent on material (adhesive system), substrate depth and adhesive/depth interaction. Hence composition and substrate treatment should be considered for good adhesive. Chemical composition of adhesive system determines

  10. Patenting biotechnologies: the European Union Directive 98/44/EC of the European parliament and of the council of 6th July 1998 on the legal protection of biotechnological inventions.

    PubMed

    Morelli Gradi, G

    1999-01-01

    Before the Directive 98/44/EC of the European Parliament and the Council of 6th July 1998, notwithstanding some decisions of the European Patent Office (still presently under opposition) and some patents already granted by the Italian Patent Office, the existing legal framework did not allow the patentability of living organisms in the European Community countries. The Directive has dramatically changed the perspectives. It ensures free circulation of patented biotechnological products harmonising the national legal system of each Member State, guaranteeing compliance with the European Patent Convention signed in Munich on 5th October 1973, the Trade-Related Aspects of Intellectual Property Rights agreement of 15th April 1994 and the Rio de Janeiro Convention on Biological Diversity of 5th June 1992. The legal basis of the Directive and the fundamental principles of protection are that discoveries as such are not considered patentable. Plant and animal varieties as such, as well as essentially biological procedures for the production of plants and animals are excluded from protection by patent. On the contrary, the new field of patentability covers plants and parts of animals with new introduced genetic characters. Methods of surgical and therapeutic treatment and diagnostic methods applied to animal bodies are not considered inventions suitable for industrial applications and excluded from protection by patents. Biological materials and material isolated from its natural environment and isolated elements of the human body with technical processes may be patented. Excluded from patentability are inventions that are contrary to law and order or public morality as well as processes for human cloning for reproductive purposes and for modifying the germ-line genetic identity of human beings, as well as the use of human embryos. The processes for modifying the genetic identity of animals without any substantial medical benefit for man (with the exception of studying new

  11. The Global Cancer Genomics Consortium: interfacing genomics and cancer medicine.

    PubMed

    2012-08-01

    The Global Cancer Genomics Consortium (GCGC) is an international collaborative platform that amalgamates cancer biologists, cutting-edge genomics, and high-throughput expertise with medical oncologists and surgical oncologists; they address the most important translational questions that are central to cancer research and treatment. The annual GCGC symposium was held at the Advanced Centre for Treatment Research and Education in Cancer, Mumbai, India, from November 9 to 11, 2011. The symposium showcased international next-generation sequencing efforts that explore cancer-specific transcriptomic changes, single-nucleotide polymorphism, and copy number variations in various types of cancers, as well as the structural genomics approach to develop new therapeutic targets and chemical probes. From the spectrum of studies presented at the symposium, it is evident that the translation of emerging cancer genomics knowledge into clinical applications can only be achieved through the integration of multidisciplinary expertise. In summary, the GCGC symposium provided practical knowledge on structural and cancer genomics approaches, as well as an exclusive platform for focused cancer genomics endeavors.

  12. Antarctic Genomics

    PubMed Central

    Clarke, Andrew; Cockell, Charles S.; Convey, Peter; Detrich III, H. William; Fraser, Keiron P. P.; Johnston, Ian A.; Methe, Barbara A.; Murray, Alison E.; Peck, Lloyd S.; Römisch, Karin; Rogers, Alex D.

    2004-01-01

    With the development of genomic science and its battery of technologies, polar biology stands on the threshold of a revolution, one that will enable the investigation of important questions of unprecedented scope and with extraordinary depth and precision. The exotic organisms of polar ecosystems are ideal candidates for genomic analysis. Through such analyses, it will be possible to learn not only the novel features that enable polar organisms to survive, and indeed thrive, in their extreme environments, but also fundamental biological principles that are common to most, if not all, organisms. This article aims to review recent developments in Antarctic genomics and to demonstrate the global context of such studies. PMID:18629155

  13. Genomic Testing

    MedlinePlus

    ... Services released a report identifying gaps in the regulation, oversight, and usefulness of genetic testing. They expressed ... December 20, 2016 Content source: Center for Surveillance, Epidemiology and Laboratory Services (CSELS) , Public Health Genomics Email ...

  14. Developing genomic resources for the apiaceae

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Apiaceae family includes carrot, celery, cilantro, dill, fennel and numerous other spice and medicinal crops. Carrot is the most economically important member of the Apiaceae with an annual value of $600 M in the United States alone. There are few genomic resources for carrot or other Apiaceae, ...

  15. Genome Sequencing.

    PubMed

    Verma, Mansi; Kulshrestha, Samarth; Puri, Ayush

    2017-01-01

    Genome sequencing is an important step toward correlating genotypes with phenotypic characters. Sequencing technologies are important in many fields in the life sciences, including functional genomics, transcriptomics, oncology, evolutionary biology, forensic sciences, and many more. The era of sequencing has been divided into three generations. First generation sequencing involved sequencing by synthesis (Sanger sequencing) and sequencing by cleavage (Maxam-Gilbert sequencing). Sanger sequencing led to the completion of various genome sequences (including human) and provided the foundation for development of other sequencing technologies. Since then, various techniques have been developed which can overcome some of the limitations of Sanger sequencing. These techniques are collectively known as "Next-generation sequencing" (NGS), and are further classified into second and third generation technologies. Although NGS methods have many advantages in terms of speed, cost, and parallelism, the accuracy and read length of Sanger sequencing is still superior and has confined the use of NGS mainly to resequencing genomes. Consequently, there is a continuing need to develop improved real time sequencing techniques. This chapter reviews some of the options currently available and provides a generic workflow for sequencing a genome.

  16. Genome databases

    SciTech Connect

    Courteau, J.

    1991-10-11

    Since the Genome Project began several years ago, a plethora of databases have been developed or are in the works. They range from the massive Genome Data Base at Johns Hopkins University, the central repository of all gene mapping information, to small databases focusing on single chromosomes or organisms. Some are publicly available, others are essentially private electronic lab notebooks. Still others limit access to a consortium of researchers working on, say, a single human chromosome. An increasing number incorporate sophisticated search and analytical software, while others operate as little more than data lists. In consultation with numerous experts in the field, a list has been compiled of some key genome-related databases. The list was not limited to map and sequence databases but also included the tools investigators use to interpret and elucidate genetic data, such as protein sequence and protein structure databases. Because a major goal of the Genome Project is to map and sequence the genomes of several experimental animals, including E. coli, yeast, fruit fly, nematode, and mouse, the available databases for those organisms are listed as well. The author also includes several databases that are still under development - including some ambitious efforts that go beyond data compilation to create what are being called electronic research communities, enabling many users, rather than just one or a few curators, to add or edit the data and tag it as raw or confirmed.

  17. Meeting Report: Genomics in the Undergraduate Curriculum--Rocket Science or Basic Science?

    ERIC Educational Resources Information Center

    Campbell, A. Malcolm

    2002-01-01

    At the 102nd annual meeting of the American Society for Microbiology (ASM) in Salt Lake City, Utah, members of the Genome Consortium for Active Teaching and faculty from around the world gathered to discuss educational genomics. The focus of the gathering was a series of presentations by faculty who have successfully incorporated genomics and…

  18. Listeria Genomics

    NASA Astrophysics Data System (ADS)

    Cabanes, Didier; Sousa, Sandra; Cossart, Pascale

    The opportunistic intracellular foodborne pathogen Listeria monocytogenes has become a paradigm for the study of host-pathogen interactions and bacterial adaptation to mammalian hosts. Analysis of L. monocytogenes infection has provided considerable insight into how bacteria invade cells, move intracellularly, and disseminate in tissues, as well as tools to address fundamental processes in cell biology. Moreover, the vast amount of knowledge that has been gathered through in-depth comparative genomic analyses and in vivo studies makes L. monocytogenes one of the most well-studied bacterial pathogens. This chapter provides an overview of progress in the exploration of genomic, transcriptomic, and proteomic data in Listeria spp. to understand genome evolution and diversity, as well as physiological aspects of metabolism used by bacteria when growing in diverse environments, in particular in infected hosts.

  19. Annual Energy Review, 2008

    SciTech Connect

    2009-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, and international energy; financial and environment indicators; and data unit conversions.

  20. Genome mapping

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Genome maps can be thought of much like road maps except that, instead of traversing across land, they traverse across the chromosomes of an organism. Genetic markers serve as landmarks along the chromosome and provide researchers information as to how close they may be to a gene or region of inter...

  1. Genome cartography: charting the apicomplexan genome.

    PubMed

    Kissinger, Jessica C; DeBarry, Jeremy

    2011-08-01

    Genes reside in particular genomic contexts that can be mapped at many levels. Historically, 'genetic maps' were used primarily to locate genes. Recent technological advances in the determination of genome sequences have made the analysis and comparison of whole genomes possible and increasingly tractable. What do we see if we shift our focus from gene content (the 'inventory' of genes contained within a genome) to the composition and organization of a genome? This review examines what has been learned about the evolution of the apicomplexan genome as well as the significance and impact of genomic location on our understanding of the eukaryotic genome and parasite biology.

  2. Personal genomics services: whose genomes?

    PubMed Central

    Gurwitz, David; Bregman-Eschet, Yael

    2009-01-01

    New companies offering personal whole-genome information services over the internet are dynamic and highly visible players in the personal genomics field. For fees currently ranging from US$399 to US$2500 and a vial of saliva, individuals can now purchase online access to their individual genetic information regarding susceptibility to a range of chronic diseases and phenotypic traits based on a genome-wide SNP scan. Most of the companies offering such services are based in the United States, but their clients may come from nearly anywhere in the world. Although the scientific validity, clinical utility and potential future implications of such services are being hotly debated, several ethical and regulatory questions related to direct-to-consumer (DTC) marketing strategies of genetic tests have not yet received sufficient attention. For example, how can we minimize the risk of unauthorized third parties from submitting other people's DNA for testing? Another pressing question concerns the ownership of (genotypic and phenotypic) information, as well as the unclear legal status of customers regarding their own personal information. Current legislation in the US and Europe falls short of providing clear answers to these questions. Until the regulation of personal genomics services catches up with the technology, we call upon commercial providers to self-regulate and coordinate their activities to minimize potential risks to individual privacy. We also point out some specific steps, along the trustee model, that providers of DTC personal genomics services as well as regulators and policy makers could consider for addressing some of the concerns raised below. PMID:19259127

  3. 2010 Annual Report

    SciTech Connect

    2010-01-01

    This annual report includes: an overview of Western; approaches for future hydropower and transmission service; major achievements in FY 2010; FY 2010 customer Integrated Resource Planning, or IRP, survey; and financial data.

  4. Citrus Genomics

    PubMed Central

    Talon, Manuel; Gmitter Jr., Fred G.

    2008-01-01

    Citrus is one of the most widespread fruit crops globally, with great economic and health value. It is among the most difficult plants to improve through traditional breeding approaches. Currently, there is risk of devastation by diseases threatening to limit production and future availability to the human population. As technologies rapidly advance in genomic science, they are quickly adapted to address the biological challenges of the citrus plant system and the world's industries. The historical developments of linkage mapping, markers and breeding, EST projects, physical mapping, an international citrus genome sequencing project, and critical functional analysis are described. Despite the challenges of working with citrus, there has been substantial progress. Citrus researchers engaged in international collaborations provide optimism about future productivity and contributions to the benefit of citrus industries worldwide and to the human population who can rely on future widespread availability of this health-promoting and aesthetically pleasing fruit crop. PMID:18509486

  5. Natural gas annual 1994

    SciTech Connect

    1995-11-17

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1994 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1990 to 1994 for each Census Division and each State. Annual historical data are shown at the national level.

  6. Natural gas annual 1995

    SciTech Connect

    1996-11-01

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1995 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1991 to 1995 for each Census Division and each State. Annual historical data are shown at the national level.

  7. TARDEC Annual Report 2010

    DTIC Science & Technology

    2011-06-15

    working on specific technologies, such as automotive capabilities, materials and software development. The benefits of these collaborations are two-fold...ANNUAL REPORT U.S. ARMY TANK AUTOMOTIVE RESEARCH, DEVELOPMENT AND ENGINEERING CENTER TWO THOUSAND TEN Report Documentation Page Form ApprovedOMB No...unlimited 13. SUPPLEMENTARY NOTES Tank- Automotive Research Development and Engineering Center (TARDEC) Fiscal Year (FY) 10 Annual Report 14. ABSTRACT

  8. Ancient genomics

    PubMed Central

    Der Sarkissian, Clio; Allentoft, Morten E.; Ávila-Arcos, María C.; Barnett, Ross; Campos, Paula F.; Cappellini, Enrico; Ermini, Luca; Fernández, Ruth; da Fonseca, Rute; Ginolhac, Aurélien; Hansen, Anders J.; Jónsson, Hákon; Korneliussen, Thorfinn; Margaryan, Ashot; Martin, Michael D.; Moreno-Mayar, J. Víctor; Raghavan, Maanasa; Rasmussen, Morten; Velasco, Marcela Sandoval; Schroeder, Hannes; Schubert, Mikkel; Seguin-Orlando, Andaine; Wales, Nathan; Gilbert, M. Thomas P.; Willerslev, Eske; Orlando, Ludovic

    2015-01-01

    The past decade has witnessed a revolution in ancient DNA (aDNA) research. Although the field's focus was previously limited to mitochondrial DNA and a few nuclear markers, whole genome sequences from the deep past can now be retrieved. This breakthrough is tightly connected to the massive sequence throughput of next generation sequencing platforms and the ability to target short and degraded DNA molecules. Many ancient specimens previously unsuitable for DNA analyses because of extensive degradation can now successfully be used as source materials. Additionally, the analytical power obtained by increasing the number of sequence reads to billions effectively means that contamination issues that have haunted aDNA research for decades, particularly in human studies, can now be efficiently and confidently quantified. At present, whole genomes have been sequenced from ancient anatomically modern humans, archaic hominins, ancient pathogens and megafaunal species. Those have revealed important functional and phenotypic information, as well as unexpected adaptation, migration and admixture patterns. As such, the field of aDNA has entered the new era of genomics and has provided valuable information when testing specific hypotheses related to the past. PMID:25487338

  9. Ancient genomics.

    PubMed

    Der Sarkissian, Clio; Allentoft, Morten E; Ávila-Arcos, María C; Barnett, Ross; Campos, Paula F; Cappellini, Enrico; Ermini, Luca; Fernández, Ruth; da Fonseca, Rute; Ginolhac, Aurélien; Hansen, Anders J; Jónsson, Hákon; Korneliussen, Thorfinn; Margaryan, Ashot; Martin, Michael D; Moreno-Mayar, J Víctor; Raghavan, Maanasa; Rasmussen, Morten; Velasco, Marcela Sandoval; Schroeder, Hannes; Schubert, Mikkel; Seguin-Orlando, Andaine; Wales, Nathan; Gilbert, M Thomas P; Willerslev, Eske; Orlando, Ludovic

    2015-01-19

    The past decade has witnessed a revolution in ancient DNA (aDNA) research. Although the field's focus was previously limited to mitochondrial DNA and a few nuclear markers, whole genome sequences from the deep past can now be retrieved. This breakthrough is tightly connected to the massive sequence throughput of next generation sequencing platforms and the ability to target short and degraded DNA molecules. Many ancient specimens previously unsuitable for DNA analyses because of extensive degradation can now successfully be used as source materials. Additionally, the analytical power obtained by increasing the number of sequence reads to billions effectively means that contamination issues that have haunted aDNA research for decades, particularly in human studies, can now be efficiently and confidently quantified. At present, whole genomes have been sequenced from ancient anatomically modern humans, archaic hominins, ancient pathogens and megafaunal species. Those have revealed important functional and phenotypic information, as well as unexpected adaptation, migration and admixture patterns. As such, the field of aDNA has entered the new era of genomics and has provided valuable information when testing specific hypotheses related to the past.

  10. Engineering Annual Summary 1998

    SciTech Connect

    Dimolitsas, S

    1999-05-01

    Unlike most research and development laboratories, Lawrence Livermore National Laboratory (LLNL) is responsible for delivering production-ready designs. Unlike most industry, LLNL is responsible for R and D that must significantly increase the nation's security. This rare combination of production engineering expertise and national R and D agenda identifies LLNL as one of the few organizations today that conducts cutting-edge engineering on grand-scale problems, while facing enormous technical risk and undergoing diligent scrutiny of its budget, schedule, and performance. On the grand scale, cutting-edge technologies are emerging from our recent ventures into ''Xtreme Engineering{trademark}.'' Basically, we must integrate and extend technologies concurrently and then push them to their extreme, such as building very large structures but aligning them with extreme precision. As we extend these technologies, we push the boundaries of engineering capabilities at both poles: microscale and ultrascale. Today, in the ultrascale realm, we are building NIF, the world's largest laser, which demands one of the world's most complex operating systems with 9000 motors integrated through over 500 computers to control 60,000 points for every laser shot. On the other pole, we have fabricated the world's smallest surgical tools and the smallest instruments for detecting biological and chemical agents used by antiterrorists. Later in this Annual Summary, we highlight some of our recent innovations in the area of Xtreme Engineering, including large-scale computer simulations of massive structures such as major bridges to prepare retrofitting designs to withstand earthquakes. Another feature is our conceptual breakthrough in developing the world's fastest airplane, HyperSoar, which can reach anywhere in the planet in two hours at speeds of 6700 mph. In the last few years, Engineering has significantly pushed the technology in structural mechanics and micro-instrumentation. For example

  11. International energy annual 1996

    SciTech Connect

    1998-02-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power, geothermal, solar, and wind electric power, biofuels energy for the US, and biofuels electric power for Brazil. New in the 1996 edition are estimates of carbon dioxide emissions from the consumption of petroleum and coal, and the consumption and flaring of natural gas. 72 tabs.

  12. Natural gas annual 1997

    SciTech Connect

    1998-10-01

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1997 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1993 to 1997 for each Census Division and each State. Annual historical data are shown at the national level. 27 figs., 109 tabs.

  13. Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)

    SciTech Connect

    Moose, Steve

    2010-03-25

    Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting

  14. Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)

    ScienceCinema

    Moose, Steve

    2016-07-12

    Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting

  15. The platypus genome unraveled.

    PubMed

    O'Brien, Stephen J

    2008-06-13

    The genome of the platypus has been sequenced, assembled, and annotated by an international genomics team. Like the animal itself the platypus genome contains an amalgam of mammal, reptile, and bird-like features.

  16. NERSC Annual Report 2005

    SciTech Connect

    Hules , John

    2006-07-31

    The National Energy Research Scientific Computing Center (NERSC) is the premier computational resource for scientific research funded by the DOE Office of Science. The Annual Report includes summaries of recent significant and representative computational science projects conducted on NERSC systems as well as information about NERSC's current and planned systems and services.

  17. Annual Research Briefs - 1996

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This report contains the 1996 annual progress reports of the research fellows and students supported by the Center for Turbulence Research. Last year, CTR hosted twelve resident Postdoctoral Fellows, three Research Associates, four Senior Research Fellows, and supported one doctoral student and ten short term visitors.

  18. Annual Coal Distribution

    EIA Publications

    2016-01-01

    The Annual Coal Distribution Report (ACDR) provides detailed information on domestic coal distribution by origin state, destination state, consumer category, and method of transportation. Also provided is a summary of foreign coal distribution by coal-producing state. All data for the report year are final and this report supersedes all data in the quarterly distribution reports.

  19. Uranium industry annual 1998

    SciTech Connect

    1999-04-22

    The Uranium Industry Annual 1998 (UIA 1998) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing. It contains data for the period 1989 through 2008 as collected on the Form EIA-858, ``Uranium Industry Annual Survey.`` Data provides a comprehensive statistical characterization of the industry`s activities for the survey year and also include some information about industry`s plans and commitments for the near-term future. Data on uranium raw materials activities for 1989 through 1998, including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment, are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2008, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, and uranium inventories, are shown in Chapter 2. The methodology used in the 1998 survey, including data edit and analysis, is described in Appendix A. The methodologies for estimation of resources and reserves are described in Appendix B. A list of respondents to the ``Uranium Industry Annual Survey`` is provided in Appendix C. The Form EIA-858 ``Uranium Industry Annual Survey`` is shown in Appendix D. For the readers convenience, metric versions of selected tables from Chapters 1 and 2 are presented in Appendix E along with the standard conversion factors used. A glossary of technical terms is at the end of the report. 24 figs., 56 tabs.

  20. Folklife Annual, 1987.

    ERIC Educational Resources Information Center

    Jabbour, Alan, Ed.; Hardin, James, Ed.

    This annual publication is intended to promote the documentation and study of the folklife of the United States, to share the traditions, values, and activities of U.S. folk culture, and to serve as a national forum for the discussion of ideas and issues in folklore and folklife. The articles in this collection are: (1) "Eating in the Belly…

  1. NRCC annual report, 1979

    SciTech Connect

    Not Available

    1980-11-01

    This annual report of the National Research for Computation in Chemistry (NRCC) Division describes the program of research workshops, software development, and scientific research of the Division in 1979. This year marked the first full calendar year of activity of the Division. Initial staffing in the core scientific areas was completed by the addition of a crystallographer.

  2. International Energy Annual, 1992

    SciTech Connect

    Not Available

    1994-01-14

    This report is prepared annually and presents the latest information and trends on world energy production and consumption for petroleum, natural gas, coal, and electricity. Trade and reserves are shown for petroleum, natural gas, and coal. Prices are included for selected petroleum products. Production and consumption data are reported in standard units as well as British thermal units (Btu) and joules.

  3. 2010 AAUW Annual Report

    ERIC Educational Resources Information Center

    American Association of University Women, 2010

    2010-01-01

    This report highlights some of the outstanding accomplishments of AAUW (American Association of University Women) for fiscal year 2010. This year's annual report also features stories of remarkable women who are leading the charge to break through barriers and ensure that all women have a fair chance. Sharon is working to reduce the pay gap…

  4. NERSC Annual Report 2002

    SciTech Connect

    Hules, John

    2003-01-31

    The National Energy Research Scientific Computing Center (NERSC) is the primary computational resource for scientific research funded by the DOE Office of Science. The Annual Report for FY2002 includes a summary of recent computational science conducted on NERSC systems (with abstracts of significant and representative projects), and information about NERSC's current and planned systems and service

  5. ASE Annual Conference 2010

    ERIC Educational Resources Information Center

    McCune, Roger

    2010-01-01

    In this article, the author describes the ASE Annual Conference 2010 which was held at Nottingham after a gap of 22 years. As always, the main conference was preceded by International Day, an important event for science educators from across the world. There were two strands to the programme: (1) "What works for me?"--sharing new ideas…

  6. UNICEF Annual Report. 1984.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This annual report reviews the work UNICEF has been doing to help transform the "Child Survival Revolution" from a dream into a reality. Discussion focuses primarily on child health and nutrition and other basic services for children. Throughout, the review is supplemented with profiles of program initiatives made to improve the…

  7. NERSC Annual Report 2004

    SciTech Connect

    Hules, John; Bashor, Jon; Yarris, Lynn; McCullough, Julie; Preuss, Paul; Bethel, Wes

    2005-04-15

    The National Energy Research Scientific Computing Center (NERSC) is the premier computational resource for scientific research funded by the DOE Office of Science. The Annual Report includes summaries of recent significant and representative computational science projects conducted on NERSC systems as well as information about NERSC's current and planned systems and services.

  8. Ultrasound Annual, 1984

    SciTech Connect

    Sanders, R.C.; Hill, M.C.

    1984-01-01

    The 1984 edition of Ultrasound Annual explores new applications of ultrasound in speech and swallowing and offers guidelines on the use of ultrasound and nuclear medicine in thyroid and biliary tract disease. Other areas covered include Doppler sonography of the abdomen, intraoperative abdominal ultrasound, sonography of the placenta, ultrasound of the neonatal head and abdomen, and sonographic echo patterns created by fat.

  9. Annual Conference Abstracts

    ERIC Educational Resources Information Center

    Journal of Engineering Education, 1972

    1972-01-01

    Includes abstracts of papers presented at the 80th Annual Conference of the American Society for Engineering Education. The broad areas include aerospace, affiliate and associate member council, agricultural engineering, biomedical engineering, continuing engineering studies, chemical engineering, civil engineering, computers, cooperative…

  10. TARDEC Annual Report 2011

    DTIC Science & Technology

    2012-01-01

    TARDEC ANNUAL REPORT 2011 35 Anniston Army Depot provides new Assault Breacher Vehicles for the U.S. Marine Corps. TARDEC’s liaison exchange...program has included Anniston Army Depot and increased communication and enabled support between the organizations. (U.S. Army photo.) DiMinishing

  11. Magnetic Resonance Annual, 1985

    SciTech Connect

    Kressel, H.Y.

    1985-01-01

    The inaugural volume of Magnetic Resonance Annual includes reviews of MRI of the posterior fossa, cerebral neoplasms, and the cardiovascular and genitourinary systems. A chapter on contrast materials outlines the mechanisms of paramagnetic contrast enhancement and highlights several promising contrast agents.

  12. UNICEF Annual Report, 1993.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This annual report for the United Nations Children's Fund (UNICEF) details the programs and services provided by this organization in 1992-93. Following an introduction by UNICEF's executive director, the report briefly reviews UNICEF activities for 1992, then describes specific projects in the following areas: (1) child survival and development;…

  13. UNICEF Annual Report 1983.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    In introducing this annual report, the executive director of UNICEF delineates the four techniques for primary health care and basic services reported in the publication "State of the World's Children, 1982-1983." The ensuing review of UNICEF's activities illustrates highlights of the year's program cooperation, including trends and key…

  14. Annual Review 1994.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    The report provides an annual report and financial review for 1994 of the Bernard van Leer Foundation, a private institution that was created for broad humanitarian purposes in 1949, and shows the varied aspects of the foundation's activities in the project field. In addition, it includes a number of feature articles which highlight specific…

  15. Annual Review 1995.

    ERIC Educational Resources Information Center

    Bernard Van Leer Foundation, The Hague (Netherlands).

    This document provides an annual report and financial review for 1995 of the Bernard van Leer Foundation, a private institution created in 1949 for broad humanitarian purposes. The report includes feature articles highlighting specific aspects of the year's activities: (1) "Growing Up in France: Parental Creches"; (2) "Changing the…

  16. Annual Conference Abstracts

    ERIC Educational Resources Information Center

    Engineering Education, 1976

    1976-01-01

    Presents the abstracts of 158 papers presented at the American Society for Engineering Education's annual conference at Knoxville, Tennessee, June 14-17, 1976. Included are engineering topics covering education, aerospace, agriculture, biomedicine, chemistry, computers, electricity, acoustics, environment, mechanics, and women. (SL)

  17. Annual Energy Outlook

    EIA Publications

    2017-01-01

    The Annual Energy Outlook provides modeled projections of domestic energy markets through 2050, and includes cases with different assumptions of macroeconomic growth, world oil prices, technological progress, and energy policies. With strong domestic production and relatively flat demand, the United States becomes a net energy exporter over the projection period in most cases.

  18. NUFFIC Annual Report, 1977.

    ERIC Educational Resources Information Center

    Netherlands Universities Foundation for International Co-operation, The Hague.

    The 1977 annual report of the Netherlands Universities Foundation for International Cooperation (NUFFIC) considers the following topics: major developments in work and policy; relationships NUFFIC has with other organizations; University Development Cooperation; developments in international education; the functioning of the Consultative Structure…

  19. Carolinas Communication Annual, 1998.

    ERIC Educational Resources Information Center

    McLennan, David B.

    1998-01-01

    This 1998 issue of "Carolinas Communication Annual" contains the following articles: "Give Me That Old Time Religion?: A Study of Religious Themes in the Rhetoric of the Ku Klux Klan" (John S. Seiter); "The Three Stooges versus the Third Reich" (Roy Schwartzman); "Interdisciplinary Team Teaching: Implementing…

  20. TACSCE Research Annual 1991.

    ERIC Educational Resources Information Center

    Lesko, Silvia Jo

    1991-01-01

    This annual contains the paper that won the 1991 President's Award of the Texas Association for Community Service and Continuing Education (TACSCE) as well as the runner-up paper and other articles. An editorial, "Learning to Crawl" (Silvia Lesko), focuses on the editor's "discovery" of the adult learner. "Ethics and…

  1. UNICEF Annual Report, 1994.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This annual report for the United Nations Children's Fund (UNICEF) describes the programs and services provided by this organization in 1993. Following an introduction by UNICEF's executive director, the report reviews regional developments in Sub-Saharan Africa, the Middle East and North Africa, East Asia and the Pacific, South Asia, Latin…

  2. Genome evolution: the dynamics of static genomes.

    PubMed

    Stechmann, Alexandra

    2004-06-22

    A random survey of a microsporidian genome has revealed some striking features. Although the genomes of microsporidians are among the smallest known for eukaryotes, their organisation appears to be well conserved.

  3. Plant Genome Duplication Database.

    PubMed

    Lee, Tae-Ho; Kim, Junah; Robertson, Jon S; Paterson, Andrew H

    2017-01-01

    Genome duplication, widespread in flowering plants, is a driving force in evolution. Genome alignments between/within genomes facilitate identification of homologous regions and individual genes to investigate evolutionary consequences of genome duplication. PGDD (the Plant Genome Duplication Database), a public web service database, provides intra- or interplant genome alignment information. At present, PGDD contains information for 47 plants whose genome sequences have been released. Here, we describe methods for identification and estimation of dates of genome duplication and speciation by functions of PGDD.The database is freely available at http://chibba.agtec.uga.edu/duplication/.

  4. Ensembl genomes 2016: more genomes, more complexity

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent...

  5. Ensembl Genomes 2016: more genomes, more complexity

    PubMed Central

    Kersey, Paul Julian; Allen, James E.; Armean, Irina; Boddu, Sanjay; Bolt, Bruce J.; Carvalho-Silva, Denise; Christensen, Mikkel; Davis, Paul; Falin, Lee J.; Grabmueller, Christoph; Humphrey, Jay; Kerhornou, Arnaud; Khobova, Julia; Aranganathan, Naveen K.; Langridge, Nicholas; Lowy, Ernesto; McDowall, Mark D.; Maheswari, Uma; Nuhn, Michael; Ong, Chuang Kee; Overduin, Bert; Paulini, Michael; Pedro, Helder; Perry, Emily; Spudich, Giulietta; Tapanari, Electra; Walts, Brandon; Williams, Gareth; Tello–Ruiz, Marcela; Stein, Joshua; Wei, Sharon; Ware, Doreen; Bolser, Daniel M.; Howe, Kevin L.; Kulesha, Eugene; Lawson, Daniel; Maslen, Gareth; Staines, Daniel M.

    2016-01-01

    Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to a rich range of data including reference sequence, gene models, transcriptional data, genetic variation and comparative analysis. This paper provides an update to the previous publications about the resource, with a focus on recent developments. These include the development of new analyses and views to represent polyploid genomes (of which bread wheat is the primary exemplar); and the continued up-scaling of the resource, which now includes over 23 000 bacterial genomes, 400 fungal genomes and 100 protist genomes, in addition to 55 genomes from invertebrate metazoa and 39 genomes from plants. This dramatic increase in the number of included genomes is one part of a broader effort to automate the integration of archival data (genome sequence, but also associated RNA sequence data and variant calls) within the context of reference genomes and make it available through the Ensembl user interfaces. PMID:26578574

  6. Ensembl Genomes 2016: more genomes, more complexity.

    PubMed

    Kersey, Paul Julian; Allen, James E; Armean, Irina; Boddu, Sanjay; Bolt, Bruce J; Carvalho-Silva, Denise; Christensen, Mikkel; Davis, Paul; Falin, Lee J; Grabmueller, Christoph; Humphrey, Jay; Kerhornou, Arnaud; Khobova, Julia; Aranganathan, Naveen K; Langridge, Nicholas; Lowy, Ernesto; McDowall, Mark D; Maheswari, Uma; Nuhn, Michael; Ong, Chuang Kee; Overduin, Bert; Paulini, Michael; Pedro, Helder; Perry, Emily; Spudich, Giulietta; Tapanari, Electra; Walts, Brandon; Williams, Gareth; Tello-Ruiz, Marcela; Stein, Joshua; Wei, Sharon; Ware, Doreen; Bolser, Daniel M; Howe, Kevin L; Kulesha, Eugene; Lawson, Daniel; Maslen, Gareth; Staines, Daniel M

    2016-01-04

    Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to a rich range of data including reference sequence, gene models, transcriptional data, genetic variation and comparative analysis. This paper provides an update to the previous publications about the resource, with a focus on recent developments. These include the development of new analyses and views to represent polyploid genomes (of which bread wheat is the primary exemplar); and the continued up-scaling of the resource, which now includes over 23 000 bacterial genomes, 400 fungal genomes and 100 protist genomes, in addition to 55 genomes from invertebrate metazoa and 39 genomes from plants. This dramatic increase in the number of included genomes is one part of a broader effort to automate the integration of archival data (genome sequence, but also associated RNA sequence data and variant calls) within the context of reference genomes and make it available through the Ensembl user interfaces.

  7. Becoming an Environmental Professional 1990. Articles from Leading Environmental Professionals on Employment and Career Trends in the 1990s--Plus Proceedings from the CEIP Fund's Annual Environmental Careers Conference, "What on Earth Can You Do?" (6th, Boston, Massachusetts, October 22, 1989).

    ERIC Educational Resources Information Center

    CEIP Fund, Inc., Cleveland, OH.

    Presented in this collection are proceedings from a conference focused on how to go about preserving and protecting the environment and attended by over 120 colleges and universities and some 60 environmental organizations, as well as 10 additional articles on careers in areas related to the environment. Included in the conference proceedings are:…

  8. Funding Opportunity: Genomic Data Centers

    Cancer.gov

    Funding Opportunity CCG, Funding Opportunity Center for Cancer Genomics, CCG, Center for Cancer Genomics, CCG RFA, Center for cancer genomics rfa, genomic data analysis network, genomic data analysis network centers,

  9. Role of genomics in eliminating health disparities

    PubMed Central

    Kashyap, Meghana V; Nolan, Michael; Sprouse, Marc; Chakraborty, Ranajit; Cross, Deanna; Roby, Rhonda; Vishwanatha, Jamboor K

    2015-01-01

    The Texas Center for Health Disparities, a National Institute on Minority Health and Health Disparities Center of Excellence, presents an annual conference to discuss prevention, awareness education, and ongoing research about health disparities both in Texas and among the national population. The 2014 Annual Texas Conference on Health Disparities brought together experts in research, patient care, and community outreach on the “Role of Genomics in Eliminating Health Disparities.” Rapid advances in genomics and pharmacogenomics are leading the field of medicine to use genetics and genetic risk to build personalized or individualized medicine strategies. We are at a critical juncture of ensuring such rapid advances benefit diverse populations. Relatively few forums have been organized around the theme of the role of genomics in eliminating health disparities. The conference consisted of three sessions addressing “Gene-Environment Interactions and Health Disparities,” “Personalized Medicine and Elimination of Health Disparities,” and “Ethics and Public Policy in the Genomic Era.” This article summarizes the basic science, clinical correlates, and public health data presented by the speakers. PMID:26435701

  10. Ontology for Genome Comparison and Genomic Rearrangements

    PubMed Central

    Flanagan, Keith; Stevens, Robert; Pocock, Matthew; Lee, Pete

    2004-01-01

    We present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further automated analysis can be built. The nomenclature defined by the ontology will foster clearer communication between biologists, and also standardize terms used by data publishers in the results of analysis programs. The overriding aim of this ontology is the facilitation of consistent annotation of genomes through computational methods, rather than human annotators. To this end, the ontology includes definitions that support computer analysis and automated transfer of annotations between genomes, rather than relying upon human mediation. PMID:18629137

  11. Enabling functional genomics with genome engineering.

    PubMed

    Hilton, Isaac B; Gersbach, Charles A

    2015-10-01

    Advances in genome engineering technologies have made the precise control over genome sequence and regulation possible across a variety of disciplines. These tools can expand our understanding of fundamental biological processes and create new opportunities for therapeutic designs. The rapid evolution of these methods has also catalyzed a new era of genomics that includes multiple approaches to functionally characterize and manipulate the regulation of genomic information. Here, we review the recent advances of the most widely adopted genome engineering platforms and their application to functional genomics. This includes engineered zinc finger proteins, TALEs/TALENs, and the CRISPR/Cas9 system as nucleases for genome editing, transcription factors for epigenome editing, and other emerging applications. We also present current and potential future applications of these tools, as well as their current limitations and areas for future advances.

  12. Enabling functional genomics with genome engineering

    PubMed Central

    Hilton, Isaac B.; Gersbach, Charles A.

    2015-01-01

    Advances in genome engineering technologies have made the precise control over genome sequence and regulation possible across a variety of disciplines. These tools can expand our understanding of fundamental biological processes and create new opportunities for therapeutic designs. The rapid evolution of these methods has also catalyzed a new era of genomics that includes multiple approaches to functionally characterize and manipulate the regulation of genomic information. Here, we review the recent advances of the most widely adopted genome engineering platforms and their application to functional genomics. This includes engineered zinc finger proteins, TALEs/TALENs, and the CRISPR/Cas9 system as nucleases for genome editing, transcription factors for epigenome editing, and other emerging applications. We also present current and potential future applications of these tools, as well as their current limitations and areas for future advances. PMID:26430154

  13. Renewable energy annual 1995

    SciTech Connect

    1995-12-01

    The Renewable Energy Annual 1995 is the first in an expected series of annual reports the Energy Information Administration (EIA) intends to publish to provide a comprehensive assessment of renewable energy. This report presents the following information on the history, status, and prospects of renewable energy data: estimates of renewable resources; characterizations of renewable energy technologies; descriptions of industry infrastructures for individual technologies; evaluations of current market status; and assessments of near-term prospects for market growth. An international section is included, as well as two feature articles that discuss issues of importance for renewable energy as a whole. The report also contains a number of technical appendices and a glossary. The renewable energy sources included are biomass (wood), municipal solid waste, biomass-derived liquid fuels, geothermal, wind, and solar and photovoltaic.

  14. International energy annual 1997

    SciTech Connect

    1999-04-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power and geothermal, solar, and wind electric power. Also included are biomass electric power for Brazil and the US, and biomass, geothermal, and solar energy produced in the US and not used for electricity generation. This report is published to keep the public and other interested parties fully informed of primary energy supplies on a global basis. The data presented have been largely derived from published sources. The data have been converted to units of measurement and thermal values (Appendices E and F) familiar to the American public. 93 tabs.

  15. Coal industry annual 1997

    SciTech Connect

    1998-12-01

    Coal Industry Annual 1997 provides comprehensive information about US coal production, number of mines, prices, productivity, employment, productive capacity, and recoverable reserves. US Coal production for 1997 and previous years is based on the annual survey EIA-7A, Coal Production Report. This report presents data on coal consumption, coal distribution, coal stocks, coal prices, and coal quality for Congress, Federal and State agencies, the coal industry, and the general public. Appendix A contains a compilation of coal statistics for the major coal-producing States. This report includes a national total coal consumption for nonutility power producers that are not in the manufacturing, agriculture, mining, construction, or commercial sectors. 14 figs., 145 tabs.

  16. Annual Energy Review 2007

    SciTech Connect

    Seiferlein, Katherine E.

    2008-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....”

  17. Annual recertification: fun? Wow!

    PubMed

    Amos, A

    1994-01-01

    Learning is critical to fostering a knowledge base required for maintaining currency and furthering professional development. In the ever-changing field of nephrology, most skills practised in nursing are considered to be sanctioned medical acts or added nursing skills. Therefore, annual recertification of the skills designated as sanctioned medical acts is an expectation of the College of Nurses of Ontario. The Wellesley Hospital policy indicates one time only or annual approval of the added nursing skills. The article will discuss the use of games as a creative, non-threatening educational tool in the recertification/re-approval process currently in place at The Wellesley Hospital, renal programs. In the past two years, several games or alternative teaching strategies have been utilized to assist the staff in preparing for recertification. This paper will examine the advantages and disadvantages of utilizing alternative teaching formats. Commentary regarding the response of staff nurses, nursing management and education will be highlighted.

  18. Petroleum marketing annual 1994

    SciTech Connect

    1995-08-24

    The Petroleum Marketing Annual (PMA) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysis, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the fob and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Annual. For this production, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication date.

  19. Navigating yeast genome maintenance with functional genomics.

    PubMed

    Measday, Vivien; Stirling, Peter C

    2016-03-01

    Maintenance of genome integrity is a fundamental requirement of all organisms. To address this, organisms have evolved extremely faithful modes of replication, DNA repair and chromosome segregation to combat the deleterious effects of an unstable genome. Nonetheless, a small amount of genome instability is the driver of evolutionary change and adaptation, and thus a low level of instability is permitted in populations. While defects in genome maintenance almost invariably reduce fitness in the short term, they can create an environment where beneficial mutations are more likely to occur. The importance of this fact is clearest in the development of human cancer, where genome instability is a well-established enabling characteristic of carcinogenesis. This raises the crucial question: what are the cellular pathways that promote genome maintenance and what are their mechanisms? Work in model organisms, in particular the yeast Saccharomyces cerevisiae, has provided the global foundations of genome maintenance mechanisms in eukaryotes. The development of pioneering genomic tools inS. cerevisiae, such as the systematic creation of mutants in all nonessential and essential genes, has enabled whole-genome approaches to identifying genes with roles in genome maintenance. Here, we review the extensive whole-genome approaches taken in yeast, with an emphasis on functional genomic screens, to understand the genetic basis of genome instability, highlighting a range of genetic and cytological screening modalities. By revealing the biological pathways and processes regulating genome integrity, these analyses contribute to the systems-level map of the yeast cell and inform studies of human disease, especially cancer.

  20. Culex genome is not just another genome for comparative genomics.

    PubMed

    Reddy, B P Niranjan; Labbé, Pierrick; Corbel, Vincent

    2012-03-30

    Formal publication of the Culex genome sequence has closed the human disease vector triangle by meeting the Anopheles gambiae and Aedes aegypti genome sequences. Compared to these other mosquitoes, Culex quinquefasciatus possesses many specific hallmark characteristics, and may thus provide different angles for research which ultimately leads to a practical solution for controlling the ever increasing burden of insect-vector-borne diseases around the globe. We argue the special importance of the cosmopolitan species- Culex genome sequence by invoking many interesting questions and the possible of potential of the Culex genome to answer those.

  1. NERSC 1998 annual report

    SciTech Connect

    Hules, John

    1999-03-01

    This 1998 annual report from the National Scientific Energy Research Computing Center (NERSC) presents the year in review of the following categories: Computational Science; Computer Science and Applied Mathematics; and Systems and Services. Also presented are science highlights in the following categories: Basic Energy Sciences; Biological and Environmental Research; Fusion Energy Sciences; High Energy and Nuclear Physics; and Advanced Scientific Computing Research and Other Projects.

  2. Annual Report 1984.

    DTIC Science & Technology

    1985-01-01

    quality activities, and coordinating activities with other Federal and non-Federal basin interests groups. - , DD Fo’N, 1473 EDITION Ort NOV6S IS...Sod•’ I TABLE OF CONTENTS (CONTINUED) PAGE SECTION VII- RESERVOIR DATA SUMMARY 1. SWD MAP 2. INDEX BY BASINS 3. INDEX IN ALPHABETICAL ORDER 4. DATA...TABLES SECTION VIII - MINUTES OF THE TRINITY RIVER BASIN INTERESTS GROUP AND THE ANNUAL SWD WATER MANAGEMENT PERSONNEL MEETING 1. TRINITY RIVER BASIN

  3. NERSC 2001 Annual Report

    SciTech Connect

    Hules, John

    2001-12-12

    The National Energy Research Scientific Computing Center (NERSC) is the primary computational resource for scientific research funded by the DOE Office of Science. The Annual Report for FY2001 includes a summary of recent computational science conducted on NERSC systems (with abstracts of significant and representative projects); information about NERSC's current systems and services; descriptions of Berkeley Lab's current research and development projects in applied mathematics, computer science, and computational science; and a brief summary of NERSC's Strategic Plan for 2002-2005.

  4. 2008 annual merit review

    SciTech Connect

    None, None

    2009-01-18

    The 2008 DOE Vehicle Technologies Program Annual Merit Review was held February 25-28, 2008 in Bethesda, Maryland. The review encompassed all of the work done by the Vehicle Technologies Program: a total of 280 individual activities were reviewed, by a total of just over 100 reviewers. A total of 1,908 individual review responses were received for the technical reviews, and an additional 29 individual review responses were received for the plenary session review.

  5. NSLS annual report 1984

    SciTech Connect

    Klaffky, R.; Thomlinson, W.

    1984-01-01

    The first comprehensive Annual Report of the National Synchrotron Light Source comes at a time of great activity and forward motion for the facility. In the following pages we outline the management changes that have taken place in the past year, the progress that has been made in the commissioning of the x-ray ring and in the enhanced utilization of the uv ring, together with an extensive discussion of the interesting scientific experiments that have been carried out.

  6. Exploring Other Genomes: Bacteria.

    ERIC Educational Resources Information Center

    Flannery, Maura C.

    2001-01-01

    Points out the importance of genomes other than the human genome project and provides information on the identified bacterial genomes Pseudomonas aeuroginosa, Leprosy, Cholera, Meningitis, Tuberculosis, Bubonic Plague, and plant pathogens. Considers the computer's use in genome studies. (Contains 14 references.) (YDS)

  7. Uranium industry annual 1994

    SciTech Connect

    1995-07-05

    The Uranium Industry Annual 1994 (UIA 1994) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing during that survey year. The UIA 1994 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. It contains data for the 10-year period 1985 through 1994 as collected on the Form EIA-858, ``Uranium Industry Annual Survey.`` Data collected on the ``Uranium Industry Annual Survey`` (UIAS) provide a comprehensive statistical characterization of the industry`s activities for the survey year and also include some information about industry`s plans and commitments for the near-term future. Where aggregate data are presented in the UIA 1994, care has been taken to protect the confidentiality of company-specific information while still conveying accurate and complete statistical data. A feature article, ``Comparison of Uranium Mill Tailings Reclamation in the United States and Canada,`` is included in the UIA 1994. Data on uranium raw materials activities including exploration activities and expenditures, EIA-estimated resources and reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities, including purchases of uranium and enrichment services, and uranium inventories, enrichment feed deliveries (actual and projected), and unfilled market requirements are shown in Chapter 2.

  8. Meeting Report: The Twelfth International Mouse Genome Conference

    SciTech Connect

    Manolakou, Katerina; Cross, Sally H.; Simpson, Eleanor H.; Jackson, Ian J.

    1998-10-01

    The annual International Mouse Genome Conference (IMGC) is where, scientifically speaking, classical mouse genetics meets the relative newcomer of genomics. The 12th meeting took place last October in the delightful Bavarian village of Garmisch-Partenkirchen, and we were greeted by the sight on the mountains of the first snowfall of the season. However the discussions left little time for exploration. Minds of participants in Garmisch were focused by a recent document produced by the NIH and by discussions within other funding agencies worldwide. If implemented, the proposals will further enhance the status of the mouse as the principal model for study of the function of the human genome.

  9. Exploiting the Genome

    DTIC Science & Technology

    1998-09-11

    complete human genome sequence . 14. SUBJECT TERMS 15. NUMBER OF PAGES 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY...goal of the project is to ob- tain the complete sequence of the human genome by the year 2005. The genome contains approximately 3.3 Gb (billion base...and second, to consider possible roles for the DOE in the "post- genomic " era, following acquisition of the complete human genome

  10. Genome Maps, a new generation genome browser

    PubMed Central

    Medina, Ignacio; Salavert, Francisco; Sanchez, Rubén; de Maria, Alejandro; Alonso, Roberto; Escobar, Pablo; Bleda, Marta; Dopazo, Joaquín

    2013-01-01

    Genome browsers have gained importance as more genomes and related genomic information become available. However, the increase of information brought about by new generation sequencing technologies is, at the same time, causing a subtle but continuous decrease in the efficiency of conventional genome browsers. Here, we present Genome Maps, a genome browser that implements an innovative model of data transfer and management. The program uses highly efficient technologies from the new HTML5 standard, such as scalable vector graphics, that optimize workloads at both server and client sides and ensure future scalability. Thus, data management and representation are entirely carried out by the browser, without the need of any Java Applet, Flash or other plug-in technology installation. Relevant biological data on genes, transcripts, exons, regulatory features, single-nucleotide polymorphisms, karyotype and so forth, are imported from web services and are available as tracks. In addition, several DAS servers are already included in Genome Maps. As a novelty, this web-based genome browser allows the local upload of huge genomic data files (e.g. VCF or BAM) that can be dynamically visualized in real time at the client side, thus facilitating the management of medical data affected by privacy restrictions. Finally, Genome Maps can easily be integrated in any web application by including only a few lines of code. Genome Maps is an open source collaborative initiative available in the GitHub repository (https://github.com/compbio-bigdata-viz/genome-maps). Genome Maps is available at: http://www.genomemaps.org. PMID:23748955

  11. Genome Maps, a new generation genome browser.

    PubMed

    Medina, Ignacio; Salavert, Francisco; Sanchez, Rubén; de Maria, Alejandro; Alonso, Roberto; Escobar, Pablo; Bleda, Marta; Dopazo, Joaquín

    2013-07-01

    Genome browsers have gained importance as more genomes and related genomic information become available. However, the increase of information brought about by new generation sequencing technologies is, at the same time, causing a subtle but continuous decrease in the efficiency of conventional genome browsers. Here, we present Genome Maps, a genome browser that implements an innovative model of data transfer and management. The program uses highly efficient technologies from the new HTML5 standard, such as scalable vector graphics, that optimize workloads at both server and client sides and ensure future scalability. Thus, data management and representation are entirely carried out by the browser, without the need of any Java Applet, Flash or other plug-in technology installation. Relevant biological data on genes, transcripts, exons, regulatory features, single-nucleotide polymorphisms, karyotype and so forth, are imported from web services and are available as tracks. In addition, several DAS servers are already included in Genome Maps. As a novelty, this web-based genome browser allows the local upload of huge genomic data files (e.g. VCF or BAM) that can be dynamically visualized in real time at the client side, thus facilitating the management of medical data affected by privacy restrictions. Finally, Genome Maps can easily be integrated in any web application by including only a few lines of code. Genome Maps is an open source collaborative initiative available in the GitHub repository (https://github.com/compbio-bigdata-viz/genome-maps). Genome Maps is available at: http://www.genomemaps.org.

  12. PREFACE: 6th European Thermal Sciences Conference (Eurotherm 2012)

    NASA Astrophysics Data System (ADS)

    Petit, Daniel; Le Niliot, Christophe

    2012-11-01

    About EUROTHERM The aim of the EUROTHERM Committee (www.eurothermcommittee.eu) is to promote and foster European cooperation in Thermal Sciences and Heat Transfer by gathering together scientists and engineers working in specialized areas. The Committee consists of members representing and appointed by national bodies in the EU countries. The current President of EUROTHERM is Professor Anton van Steenhoven from the University of Eindhoven (The Netherlands). The Committee organizes and coordinates European scientific events such as the EUROTHERM Seminars (about 4 per year) and the European Thermal Sciences Conference (every 4 years). About the conference This sixth in the series of European Thermal Sciences Conferences (www.eurotherm2012.com) took place in France, in the Conference Centre of Poitiers, Futuroscope. We address special thanks to the 225 reviewers, coming from different European countries, who have evaluated these papers. We also thank the scientific committee, consisting of some EUROTHERM Committee members together with other internationally recognized experts. Their role has been to manage the evaluation of abstracts and the papers selection process as co-coordinators for specific topics. This conference is the joint effort of two laboratories: the PPRIME Institute in Poitiers and the IUSTI laboratory in Marseille. It could not be organized without the efficient help of our secretaries and our technician for the IT support. This volume of Journal of Physics: Conference Series includes 180 articles presented at the conference. Professor Daniel PETIT Chairman, PPRIME Poitiers, France Institut P'(UPR CNRS 3346) ENSMA 1 av. Clément Ader - BP40109 86961 Futuroscope-Chasseneuil France daniel.petit@ensma.fr Professor Christophe LE NILIOT Co-chairman, IUSTI Marseille, France Laboratoire IUSTI UMR CNRS 6595 Technopôle de Chateau-Gombert 5, rue Enrico Fermi 13 453 MARSEILLE CEDEX 13 France christophe.leniliot@polytech.univ-mrs.fr

  13. Environmental Studies Center Teacher Books. 6th Grade - River Investigation.

    ERIC Educational Resources Information Center

    Martin County Schools, Jensen Beach, FL. Environmental Studies Center.

    This teacher's guide, one of nine teacher packages developed for use in the sequential, hands-on, field-oriented, K-8 environmental education program of the Martin County Schools in Florida, was developed for use with elementary children in grade six prior to and after a visit to an environmental studies center located near an estuarine area. The…

  14. Career Motivation Activities Guide, 4th through 6th Grade.

    ERIC Educational Resources Information Center

    Toledo Public Schools, OH.

    The activities guide is intended primarily to assist teachers in grades 4-7 in teaching career awareness concepts. Instructional activities correlate basic skill and career education objectives. The 29 units cover topics related to social studies (self-awareness, the community, the school, transportation, the environment, family roles, economic…

  15. Nutrition Super Stars [5th and 6th Grades].

    ERIC Educational Resources Information Center

    Houtkooper, Linda; And Others

    This nutrition and physical fitness curriculum kit provides a means for students, teachers, parents, and school health and food service staff to learn about the nutritional value of food and the relationship of food and physical fitness to growth, development, and health; develop food and activity habits which promote good health; and share this…

  16. Annotated Bibliography for 6th Grade Science and Social Studies.

    ERIC Educational Resources Information Center

    Randolph, Margo

    Designed to support curriculum and to facilitate instruction and learning at the sixth grade level, this annotated bibliography contains materials found in the library at the Brawley Middle School in Scotland Neck, North Carolina. To foster cooperative planning between teacher and librarian, the bibliography provides sample activities and lessons…

  17. Keynote Address for 6th International Symposium on Digital Earth

    NASA Technical Reports Server (NTRS)

    Bambacus, Myra

    2009-01-01

    NASA is committed to collaborating with not only our National Partners but also with our International Partners to help make our world a better place. We do this through the sharing of our discoveries and working together so that we can address uncertainties in predictions and forecasts that impact how we live on our home planet. NASA is committed to a Digital Earth as it enables our research to focus on cross disciplinary analysis. The mainstream Information Technologies along with the Digital Earth concepts have allowed this interdisciplinary research that is so critical to societal benefits. The technologies have been discovered and in many cases implemented, but we must forge ahead together to continue to advance all that is possible to fully extend our earth observations for the sake of humankind.

  18. PREFACE: 6th International Conference on Aperiodic Crystals (APERIODIC'09)

    NASA Astrophysics Data System (ADS)

    Grimm, Uwe; McGrath, Rónán; Degtyareva, Olga; Sharma, Hem Raj

    2010-04-01

    Aperiodic Logo Aperiodic'09, the sixth International Conference on Aperiodic Crystals, took place in Liverpool 13-18 September 2009. It was the first major conference in this interdisciplinary research field held in the UK. The conference, which was organised under the auspices of the Commission on Aperiodic Crystals of the International Union of Crystallography (IUCr), followed on from Aperiodic'94 (Les Diablerets, Switzerland), Aperiodic'97 (Alpe d'Huez, France), Aperiodic'2000 (Nijmegen, The Netherlands), Aperiodic'03 (Belo Horizonte, Brazil) and Aperiodic'06 (Zao, Japan). The next conference in the series will take place in Australia in 2012. The Aperiodic conference series is itself the successor to a series of Conferences on Modulated Structures, Polytypes and Quasicrystals (MOSPOQ), which were held in Marseilles (France) in 1984, Wroclaw (Poland) in 1986, Varanasi (India) in 1988 and Balatonszeplak (Hungary) in 1991. The remit of the conference covers two broad areas of research on aperiodic crystals, incommensurately modulated and composite crystals on the one hand, and quasicrystals on the other hand, sharing the property that they are aperiodically ordered solids. In addition, the conference also featured recent research on complex metal alloys, which are in fact periodically ordered solids. However, the term complex refers to their large unit cells, which may contain thousands of atoms, and as a consequence complex metal alloys share some of the properties of quasicrystalline solids. Aperiodic'09 attracted about 110 participants from across the world, including 20 UK-based scientists (the second largest group after Japan who sent 21 delegates). A particular feature of the conference series is its interdisciplinary character, and once again the range of disciplines of participants included mathematics, physics, crystallography and materials science. The programme started with three tutorial lectures on Sunday afternoon, presenting introductory overviews on quasicrystals (Eiji Abe), complex metal alloys (Alessandra Beni) and incommensurately modulated structures (Gervais Chapuis). While these were mainly aimed at younger researchers in the field, the lectures were very well attended and appreciated by the participants. The main programme ran from Monday morning until Friday lunchtime. It comprised 13 invited and 40 contributed plenary talks, and more than 40 posters, which were presented at two afternoon/evening poster sessions. The topics covered in the programme range from mathematical foundations, mathematical models, new materials, sample preparation, structure determination, physical properties and surface properties to industrial applications. Every presenter was invited to submit an article for this proceedings volume, and the 36 peer-reviewed papers in this volume present a cross-section of the range of presentations at the conference. They have been arranged into four categories, (i) quasicrystals, (ii) modulated structures, (iii) mathematical and theoretical aspects of aperiodic order, and (iv) approximants and complex phases. Prizes for best student presentations were awarded to Heinrich Orsini-Rosenberg (ETH Zurich) for his poster Tailor-made sevenfold approximants: ab-initio investigations on formation and stability and to Holger Euchner (Universität Stuttgart) for his contributed talk on Lattice dynamics in complex metallic alloys - vibrational properties of Zn11Mg2. In addition to a cash prize, Heinrich Orsini-Rosenberg received an icosahedral teapot, which was manufactured and donated by David Warrington, and Holger Euchner received a book prize. The meeting started with a welcome reception in the University's recently refurbished Victoria Gallery and Museum. A public lecture Simple sets of shapes that tile the plane but cannot ever repeat by Professor Sir Roger Penrose FRS attracted a wide audience and gave a fascinating insight into the discovery of the Penrose tiling, which is still the paradigm of aperiodic order in two dimensions and used in modelling quasicrystalline materials, some ten years before quasicrystals were first seen in experiment. The conference excursion and dinner centred on the historic waterfront area of this 800-year old city that was designated European Capital of Culture in 2008. The enjoyment of the ferry trip on the Mersey and subsequent walk to the Albert dock museums was greatly enhanced by the fine weather, which lasted throughout the entire conference week. The guests of honour at the conference dinner were Professor Sir Roger Penrose FRS and Professor Alan L Mackay FRS, bringing together two distinguished UK scientists who made seminal contributions to the subject. Besides the scientific programme, the conference also offered a presentation by the author Ann Lingard, whose latest novel The Embalmer's Book of Recipes features a mathematician working on quasicrystals at the University of Liverpool as its main character. A related EPSRC-supported workshop on Mathematical Aspects of Aperiodic Order, organised by Alex Clark, John Hunton and Uwe Grimm, was held in Leicester in the week preceding the conference, and attracted about 40 participants. It is not possible to organise a conference without the help and support of a large number of people, and we would like to take this opportunity to acknowledge the support of everyone who was involved in organising and running this conference. We would like to thank the IUCr Aperiodic Commission, and in particular its chair Professor Marc de Boissieu, who not only entrusted us with hosting the event, but acted as the International Advisory Committee and provided valuable advice and guidance. We are indebted to the members of the International Programme Committee, who helped to put together an exciting programme by suggesting invited speakers and selecting presentations for contributed plenary talks. We are immensely grateful to all members of the National Organising Committee, who provided essential support during the organising stage and during the conference itself, and we would particularly like to thank the conference secretary, Mrs Angie Reid, for her excellent administrative support before, during and after the conference, and for her help in the production of this volume. We are very much indebted to out co-editors, Dr Olga Degtyareva (Edinburgh) and Dr Hem Raj Sharma (Liverpool), for their contributions to the editing of this volume. Finally, and most of all, we would like to thank all participants of the conference for coming to Liverpool, for contributing by presenting their recent work and taking part in discussions, and for creating such an enjoyable and fruitful collegiate atmosphere throughout the week. Last but not least we would like to express our gratitude for the generous financial support we received from the Open University, the University of Liverpool and the Institute of Physics (Mathematical and Theoretical Physics Group and Thin Films and Surfaces Group). The International Union of Crystallography provided financial sponsorship which was allocated to support the participation of 15 young scientists. The European Network of Excellence on Complex Metallic Alloys provided travel and subsistence support to members of participating organisations. Rónán McGrath Uwe Grimm Conference photograph

  19. Physics, Laboratory Manual-Student Version , 6th Edition

    NASA Astrophysics Data System (ADS)

    Cutnell, John D.; Johnson, Kenneth W.

    2004-01-01

    This Sixth Edition helps readers understand the interrelationships among basic physics concepts and how they fit together to describe our physical world. Throughout the book, the authors emphasize the relevance of physics to our everyday lives. Real-world physics applications, including many biomedical applications, show how physics principles come into play over and over again in our lives. Problem Solving Insights explain each calculation in detail, guiding readers through the quantitative process Includes a CD containing physics simulations

  20. Physics, AP Student Study Guide, 6th Edition

    NASA Astrophysics Data System (ADS)

    Cutnell, John D.; Johnson, Kenneth W.

    2003-11-01

    This Sixth Edition helps readers understand the interrelationships among basic physics concepts and how they fit together to describe our physical world. Throughout the book, the authors emphasize the relevance of physics to our everyday lives. Real-world physics applications, including many biomedical applications, show how physics principles come into play over and over again in our lives. Problem Solving Insights explain each calculation in detail, guiding readers through the quantitative process Includes a CD containing physics simulations

  1. General Chemistry Collection for Students, 6th Edition

    NASA Astrophysics Data System (ADS)

    2002-05-01

    System requirements are given in Tables 2a and b. Some programs have additional special requirements. Please see the individual program abstracts at JCE Online or the documentation included on the CD-ROM for more specific information.

    Table 2a. Hardware Required
    Computer CPU RAM Drives Graphics
    Mac OS Power Macintosh ≥ 64 MB CD-ROMHard Drive ≥ 256 colors;≥ 800x600
    Windows Pentium ≥ 64 MB CD-ROMHard Drive SVGA;≥ 256 colors;≥ 800x600
    Table 2b. Software Required
  2. Multicultural Education: Issues and Perspectives. 6th Edition

    ERIC Educational Resources Information Center

    Banks, James A.; Banks, Cherry A. McGee

    2006-01-01

    Today's classrooms are more diverse than ever before. In order to reach these students, educators must be aware of the issues facing their various cultural, racial, ethnic, and language groups. Focusing on the pertinent issues in multicultural education, this new edition raises these critical issues and facilitates meaningful discussion. It has…

  3. Careers and the Study of Political Science. 6th Edition

    ERIC Educational Resources Information Center

    American Political Science Association (NJ3), 2003

    2003-01-01

    This guide is a great resource for today's undergraduate. This updated career guide explores the many career options available to political science students and emphasizes the value of political science training. In additional to providing specific information about various career paths, this guide will help students examine their own career…

  4. Materiel Testing in the Tropics (6th Ed)

    DTIC Science & Technology

    1979-04-01

    ceramics Test methodology Panama Canal Zone Textiles Plastics Tropic Test Center Protective coatings Tropical animals 20. (cont) of Materiel Testing in...Canal Zone . .. 1-3 D Materiel Testing in the Panama Canal Zone . . . . . . . ... . 1-5 E Canal Zone Environment--Brief Overview .. .. .... ...... 1-6...trapped there, and by the heavy biomass of the canopy itself. E. CANAL ZONE ENVIRONMENT--BRIEF OVERVIEW The Canal Zone (see frontispiece) bisects the

  5. Belt conveyors for bulk materials. 6th ed.

    SciTech Connect

    2007-07-01

    The 16 chapters are entitled: Belt conveyor general applications economics; Design considerations; Characteristics and conveyability of bulk materials; Capacities, belt widths and speeds; Belt conveyor idlers; Belt tension and power engineering; Belt selection; Pulleys and shafts; Curves; Steep angle conveying; Belt cleaners and accessories; Transfer points; Conveyor motor drives and controls; Operation, maintenance and safety; Belt takeups; and Emerging technologies. 6 apps.

  6. JGI Fungal Genomics Program

    SciTech Connect

    Grigoriev, Igor V.

    2011-03-14

    Genomes of energy and environment fungi are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 50 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such 'parts' suggested by comparative genomics and functional analysis in these areas are presented here

  7. Genomic Encyclopedia of Fungi

    SciTech Connect

    Grigoriev, Igor

    2012-08-10

    Genomes of fungi relevant to energy and environment are in focus of the Fungal Genomic Program at the US Department of Energy Joint Genome Institute (JGI). Its key project, the Genomics Encyclopedia of Fungi, targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts), and explores fungal diversity by means of genome sequencing and analysis. Over 150 fungal genomes have been sequenced by JGI to date and released through MycoCosm (www.jgi.doe.gov/fungi), a fungal web-portal, which integrates sequence and functional data with genome analysis tools for user community. Sequence analysis supported by functional genomics leads to developing parts list for complex systems ranging from ecosystems of biofuel crops to biorefineries. Recent examples of such parts suggested by comparative genomics and functional analysis in these areas are presented here.

  8. Annual Research Briefs, 1990

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The 1990 annual progress reports of the Research Fellows and students of the Center for Turbulent Research (CTR) are included. It is intended primarily as a contractor report to NASA, Ames Research Center. In addition, numerous CTR Manuscript Reports were published last year. The purpose of the CTR Manuscript Series is to expedite the dissemination of research results by the CTR staff. The CTR is devoted to the fundamental study of turbulent flow; its objectives are to produce advances in physical understanding of turbulence, in turbulence modeling and simulation, and in turbulence control.

  9. Renewable energy annual 1996

    SciTech Connect

    1997-03-01

    This report presents summary data on renewable energy consumption, the status of each of the primary renewable technologies, a profile of each of the associated industries, an analysis of topical issues related to renewable energy, and information on renewable energy projects worldwide. It is the second in a series of annual reports on renewable energy. The renewable energy resources included in the report are biomass (wood and ethanol); municipal solid waste, including waste-to-energy and landfill gas; geothermal; wind; and solar energy, including solar thermal and photovoltaic. The report also includes various appendices and a glossary.

  10. International energy annual 1995

    SciTech Connect

    1996-12-01

    The International Energy Annual presents information and trends on world energy production and consumption for petroleum, natural gas, coal, and electricity. Production and consumption data are reported in standard units as well as British thermal units (Btu). Trade and reserves are shown for petroleum, natural gas, and coal. Data are provided on crude oil refining capacity and electricity installed capacity by type. Prices are included for selected crude oils and for refined petroleum products in selected countries. Population and Gross Domestic Product data are also provided.

  11. Nuclear medicine annual, 1987

    SciTech Connect

    Freeman, L.M.; Weissmann, H.S.

    1987-01-01

    Radionuclide evaluation of brain death, bone imaging with SPECT, and lymphoscintigraphy are among the topics covered in Nuclear Medicine Annual, 1987. In addition, the book includes reviews of the role of nuclear medicine in the diagnosis of the Acquired Immunodeficiency Syndrome (AIDS) and in the management of patients with acute myocardial infarction. Reports describe advances in radionuclide and magnetic resonance imaging of the adrenal gland and assess the current status of diuretic renography. Also included are articles on changes in functional imaging with aging, on radionuclide evaluation of the lower genitourinary tract in children, and on cholescintigraphy in children.

  12. Annual Energy Review 2001

    SciTech Connect

    Seiferlein, Katherine E.

    2002-11-01

    The Annual Energy Review (AER) is a statistical history of energy activities in the United States. It documents trends and milestones in U.S. energy production, trade, storage, pricing, and consumption. Each new year of data that is added to the time series—which now reach into 7 decades—extends the story of how Americans have acquired and used energy. It is a story of continual change as the Nation's economy grew, energy requirements expanded, resource availability shifted, and interdependencies developed among nations.

  13. NPL 1999 Annual Report

    SciTech Connect

    2000-01-01

    OAK-B135 NPL 1999 Annual Report. The Nuclear Physics Laboratory at the University of Washington in Seattle pursues a broad program of nuclear physics research. Research activities are conducted locally and at remote sites. The current program includes ''in-house'' research on nuclear collisions using the local tandem Van de Graaff and superconducting linac accelerators as well as local and remote non-accelerator research on fundamental symmetries and weak interactions and user-mode research on relativistic heavy ions at large accelerator facilities around the world.

  14. Annual report to Congress

    SciTech Connect

    1992-03-01

    This is the eighth annual report submitted by the Office of Civilian Radioactive Waste Management (OCRWM) to Congress. It covers activities and expenditures during Fiscal Year 1991, which ended September 30, 1991. Chapter 1 of this report describes OCRWM`s mission and objectives. Chapters 2 through 8 cover the following topics: earning public trust and confidence; geological disposal; monitored retrieval storage; transportation; systems integration and regulatory compliance; international programs; and program management. Financial statements for the Nuclear Waste Fund are presented in Chapter 9.

  15. Annual Energy Review 2010

    SciTech Connect

    2011-10-01

    This twenty-ninth edition of the Annual Energy Review (AER) presents the U.S. Energy Information Administration’s (EIA) most comprehensive look at integrated energy statistics. The summary statistics on the Nation’s energy production, consumption, trade, stocks, and prices cover all major energy commodities and all energy-consuming sectors of the U.S. economy from 1949 through 2010. The AER is EIA’s historical record of energy statistics and, because the coverage spans six decades, the statistics in this report are well-suited to long-term trend analysis.

  16. Annual Research Briefs - 2006

    DTIC Science & Technology

    2006-12-01

    a round liq- uid jet by a coaxial flow of gas. D. KIM, 0. DESJARDINS, MI. HERRMANN AND P. MOIN 185 Stable and high-order accurate finite difference...Research 185 Annual Research Briefs 2006 Toward two-phase simulation of the primary breakup of a round liquid jet by a coaxial flow of gas By D. Kim, 0...gas phase. The flow solver volume fraction i) is defined as The breakup of a round liquid jet by a coaxial flow of gas 187 Vi = ’ H(G)dV, (2.9) where

  17. Annual research briefs, 1989

    NASA Technical Reports Server (NTRS)

    Spinks, Debra (Compiler)

    1990-01-01

    This report contains the 1989 annual progress reports of the Research Fellows of the Center for Turbulence Research. It is intended as a year end report to NASA, Ames Research Center which supports this group through core funding and by making available physical and intellectual resources. The Center for Turbulence Research is devoted to the fundamental study of turbulent flows; its objectives are to simulate advances in the physical understanding of turbulence, in turbulence modeling and simulation, and in turbulence control. The reports appearing in the following pages are grouped in the general areas of modeling, experimental research, theory, simulation and numerical methods, and compressible and reacting flows.

  18. Nuclear Medicine Annual, 1989

    SciTech Connect

    Freeman, L.M.; Weissmann, H.S.

    1989-01-01

    Among the highlights of Nuclear Medicine Annual, 1989 are a status report on the thyroid scan in clinical practice, a review of functional and structural brain imaging in dementia, an update on radionuclide renal imaging in children, and an article outlining a quality assurance program for SPECT instrumentation. Also included are discussions on current concepts in osseous sports and stress injury scintigraphy and on correlative magnetic resonance and radionuclide imaging of bone. Other contributors assess the role of nuclear medicine in clinical decision making and examine medicolegal and regulatory aspects of nuclear medicine.

  19. Ultrasound Annual, 1983

    SciTech Connect

    Sanders, R.C.; Hill, M.C.

    1983-01-01

    The 1983 edition of Ultrasound Annual features a state-of-the-art assessment of real-time ultrasound technology and a look at improvements in real-time equipment. Chapters discuss important new obstetric applications of ultrasound in measuring fetal umbilical vein blood flow and monitoring ovarian follicular development in vivo and in vitro fertilization. Other topics covered include transrectal prostate ultrasound using a linear array system; ultrasound of the common bile duct; ultrasound in tropical diseases; prenatal diagnosis of craniospinal anomalies; scrotal ultrasonography; opthalmic ultrasonography; and sonography of the upper abdominal venous system.

  20. Plant genomics: an overview.

    PubMed

    Campos-de Quiroz, Hugo

    2002-01-01

    Recent technological advancements have substantially expanded our ability to analyze and understand plant genomes and to reduce the gap existing between genotype and phenotype. The fast evolving field of genomics allows scientists to analyze thousand of genes in parallel, to understand the genetic architecture of plant genomes and also to isolate the genes responsible for mutations. Furthermore, whole genomes can now be sequenced. This review addresses these issues and also discusses ways to extract biological meaning from DNA data. Although genomic issuesare addressed from a plant perspective, this review provides insights into the genomic analyses of other organisms.

    1. Genomics on the Half Shell: So, What do Oysters Have to do with Energy? (2010 JGI User Meeting)

      SciTech Connect

      Hedgecock, Dennis

      2010-03-24

      Dennis Hedgecock from the University of Southern California answers the question, "Genomics on the Half Shell: So, What Do Oysters Have to Do with Energy?" on March 24, 2010 at the 5th Annual DOE JGI User Meeting

    2. Genomics on the Half Shell: So, What do Oysters Have to do with Energy? (2010 JGI User Meeting)

      ScienceCinema

      Hedgecock, Dennis

      2016-07-12

      Dennis Hedgecock from the University of Southern California answers the question, "Genomics on the Half Shell: So, What Do Oysters Have to Do with Energy?" on March 24, 2010 at the 5th Annual DOE JGI User Meeting

    3. Electric power annual 1992

      SciTech Connect

      Not Available

      1994-01-06

      The Electric Power Annual presents a summary of electric utility statistics at national, regional and State levels. The objective of the publication is to provide industry decisionmakers, government policymakers, analysts and the general public with historical data that may be used in understanding US electricity markets. The Electric Power Annual is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA); US Department of Energy. ``The US Electric Power Industry at a Glance`` section presents a profile of the electric power industry ownership and performance, and a review of key statistics for the year. Subsequent sections present data on generating capability, including proposed capability additions; net generation; fossil-fuel statistics; retail sales; revenue; financial statistics; environmental statistics; electric power transactions; demand-side management; and nonutility power producers. In addition, the appendices provide supplemental data on major disturbances and unusual occurrences in US electricity power systems. Each section contains related text and tables and refers the reader to the appropriate publication that contains more detailed data on the subject matter. Monetary values in this publication are expressed in nominal terms.

    4. CMS Annual Report 2004

      SciTech Connect

      de la Rubia, T D; Shang, S P; Rennie, G; Fluss, M; Westbrook, C

      2005-07-29

      Glance at the articles in this report, and you will sense the transformation that is reshaping the landscape of materials science and chemistry. This transformation is bridging the gaps among chemistry, materials science, and biology--ushering in a wealth of innovative technologies with broad scientific impact. The emergence of this intersection is reinvigorating our strategic investment into areas that build on our strength of interdisciplinary science. It is at the intersection that we position our strategic vision into a future where we will provide radical materials innovations and solutions to our national-security programs and other sponsors. Our 2004 Annual Report describes how our successes and breakthroughs follow a path set forward by our strategic plan and four organizing research themes, each with key scientific accomplishments by our staff and collaborators. We have organized this report into two major sections: research themes and our dynamic teams. The research-theme sections focus on achievements arising from earlier investments while addressing future challenges. The dynamic teams section illustrates the directorate's organizational structure of divisions, centers, and institutes that support a team environment across disciplinary and institutional boundaries. The research presented in this annual report gives substantive examples of how we are proceeding in each of these four theme areas and how they are aligned with our national-security mission. By maintaining an organizational structure that offers an environment of collaborative problem-solving opportunities, we are able to nurture the discoveries and breakthroughs required for future successes.

    5. Annual Energy Review 2005

      SciTech Connect

      Seiferlein, Katherine E.

      2006-07-01

      The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

    6. Annual Energy Review 2004

      SciTech Connect

      Seiferlein, Katherine E.

      2005-08-01

      The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

    7. Annual Energy Review 2006

      SciTech Connect

      Seiferlein, Katherine E.

      2007-06-01

      The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

    8. Annual Energy Review 2009

      SciTech Connect

      Fichman, Barbara T.

      2010-08-01

      The Annual Energy Review (AER) is the U.S. Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, and international energy; financial and environment indicators; and data unit conversions. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding the content of the AER and other EIA publications.

    9. Annual Energy Review 1993

      SciTech Connect

      Not Available

      1994-07-14

      This twelfth edition of the Annual Energy Review (AER) presents the Energy Information Administration`s historical energy statistics. For most series, statistics are given for every year from 1949 through 1993. Because coverage spans four and a half decades, the statistics in this report are well-suited to long-term trend analyses. The AER is comprehensive. It covers all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels and electricity. The AER also presents Energy Information Administration (EIA) statistics on some renewable energy sources. EIA estimates that its consumption series include about half of the renewable energy used in the United States. For a more complete discussion of EIA`s renewables data, see p. xix, ``Introducing Expanded Coverage of Renewable Energy Data Into the Historical Consumption Series.`` Copies of the 1993 edition of the Annual Energy Review may be obtained by using the order form in the back of this publication. Most of the data in the 1993 edition also are available on personal computer diskette. For more information about the diskettes, see the back of this publication. In addition, the data are available as part of the National Economic, Social, and Environmental Data Bank on a CD-ROM. For more information about the data bank, contact the US Department of Commerce Economics and Statistics Administration, on 202-482-1986.

    10. Annual Energy Review 2011

      SciTech Connect

      Fichman, Barbara T.

      2012-09-01

      The Annual Energy Review (AER) is the U.S. Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, and renewable energy; financial and environment indicators; and data unit conversions. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding the content of the AER and other EIA publications.

    11. Integrating sequence, evolution and functional genomics in regulatory genomics

      PubMed Central

      Vingron, Martin; Brazma, Alvis; Coulson, Richard; van Helden, Jacques; Manke, Thomas; Palin, Kimmo; Sand, Olivier; Ukkonen, Esko

      2009-01-01

      With genome analysis expanding from the study of genes to the study of gene regulation, 'regulatory genomics' utilizes sequence information, evolution and functional genomics measurements to unravel how regulatory information is encoded in the genome. PMID:19226437

    12. Genomic Data Commons | Office of Cancer Genomics

      Cancer.gov

      The NCI’s Center for Cancer Genomics launches the Genomic Data Commons (GDC), a unified data sharing platform for the cancer research community. The mission of the GDC is to enable data sharing across the entire cancer research community, to ultimately support precision medicine in oncology.

    13. Directed genome engineering for genome optimization.

      PubMed

      D'Halluin, Kathleen; Ruiter, Rene

      2013-01-01

      The ability to develop nucleases with tailor-made activities for targeted DNA double-strand break induction at will at any desired position in the genome has been a major breakthrough to make targeted genome optimization feasible in plants. The development of site specific nucleases for precise genome modification has expanded the repertoire of tools for the development and optimization of traits, already including mutation breeding, molecular breeding and transgenesis.Through directed genome engineering technology, the huge amount of information provided by genomics and systems biology can now more effectively be used for the creation of plants with improved or new traits, and for the dissection of gene functions. Although still in an early phase of deployment, its utility has been demonstrated for engineering disease resistance, herbicide tolerance, altered metabolite profiles, and for molecular trait stacking to allow linked transmission of transgenes. In this article, we will briefly review the different approaches for directed genome engineering with the emphasis on double strand break (DSB)-mediated engineering to-wards genome optimization for crop improvement and towards the acceleration of functional genomics.

    14. GENOMICS AND ENVIRONMENTAL RESEARCH

      EPA Science Inventory

      The impact of recently developed and emerging genomics technologies on environmental sciences has significant implications for human and ecological risk assessment issues. The linkage of data generated from genomics, transcriptomics, proteomics, metabalomics, and ecology can be ...

    15. Genomic Data Commons launches

      Cancer.gov

      The Genomic Data Commons (GDC), a unified data system that promotes sharing of genomic and clinical data between researchers, launched today with a visit from Vice President Joe Biden to the operations center at the University of Chicago.

    16. Annual Energy Review 1999

      SciTech Connect

      Seiferlein, Katherine E.

      2000-07-01

      A generation ago the Ford Foundation convened a group of experts to explore and assess the Nation’s energy future, and published their conclusions in A Time To Choose: America’s Energy Future (Cambridge, MA: Ballinger, 1974). The Energy Policy Project developed scenarios of U.S. potential energy use in 1985 and 2000. Now, with 1985 well behind us and 2000 nearly on the record books, it may be of interest to take a look back to see what actually happened and consider what it means for our future. The study group sketched three primary scenarios with differing assumptions about the growth of energy use. The Historical Growth scenario assumed that U.S. energy consumption would continue to expand by 3.4 percent per year, the average rate from 1950 to 1970. This scenario assumed no intentional efforts to change the pattern of consumption, only efforts to encourage development of our energy supply. The Technical Fix scenario anticipated a “conscious national effort to use energy more efficiently through engineering know-how." The Zero Energy Growth scenario, while not clamping down on the economy or calling for austerity, incorporated the Technical Fix efficiencies plus additional efficiencies. This third path anticipated that economic growth would depend less on energy-intensive industries and more on those that require less energy, i.e., the service sector. In 2000, total energy consumption was projected to be 187 quadrillion British thermal units (Btu) in the Historical Growth case, 124 quadrillion Btu in the Technical Fix case, and 100 quadrillion Btu in the Zero Energy Growth case. The Annual Energy Review 1999 reports a preliminary total consumption for 1999 of 97 quadrillion Btu (see Table 1.1), and the Energy Information Administration’s Short-Term Energy Outlook (April 2000) forecasts total energy consumption of 98 quadrillion Btu in 2000. What energy consumption path did the United States actually travel to get from 1974, when the scenarios were drawn

    17. Whole-genome patenting.

      PubMed

      O'Malley, Maureen A; Bostanci, Adam; Calvert, Jane

      2005-06-01

      Gene patenting is now a familiar commercial practice, but there is little awareness that several patents claim ownership of the complete genome sequence of a prokaryote or virus. When these patents are analysed and compared to those for other biological entities, it becomes clear that genome patents seek to exploit the genome as an information base and are part of a broader shift towards intangible intellectual property in genomics.

    18. Exploiting the genome

      SciTech Connect

      Block, S.; Cornwall, J.; Dyson, F.; Koonin, S.; Lewis, N.; Schwitters, R.

      1998-09-11

      In 1997, JASON conducted a DOE-sponsored study of the human genome project with special emphasis on the areas of technology, quality assurance and quality control, and informatics. The present study has two aims: first, to update the 1997 Report in light of recent developments in genome sequencing technology, and second, to consider possible roles for the DOE in the ''post-genomic" era, following acquisition of the complete human genome sequence.

    19. The 50th Annual Maize Genetics Conference

      SciTech Connect

      Cone, Karen

      2014-03-26

      The 50th Annual Maize Genetics Conference was held February 27 - March 2, 2008 at the Marriott Wardman Park Hotel in Washington, D.C. As the golden anniversary of the Conference and coinciding with the release of a draft of the maize genome sequence, this was a special meeting. To publicize this unique occasion, meeting organizers hosted a press conference, which was attended by members of the press representing science and non-science publications, and an evening reception at the Smithsonian National Museum of Natural History, where the draft sequence was announced and awards were presented to Dr. Mary Clutter and Senator Kit Bond to thank them for their outstanding contributions to maize genetics and genomics research. As usual, the Conference provided an invigorating forum for exchange of recent research results in many areas of maize genetics, e.g., cytogenetics, development, molecular genetics, transposable element biology, biochemical genetics, and genomics. Results were shared via both oral and poster presentations. Invited talks were given by four distinguished geneticists: Vicki Chandler, University of Arizona; John Doebley, University of Wisconsin; Susan Wessler, University of Georgia; and Richard Wilson, Washington University. There were 46 short talks and 241 poster presentations. The Conference was attended by over 500 participants. This included a large number of first-time participants in the meeting and an increasingly visible presence by individuals from underrepresented groups. Although we do not have concrete counts, there seem to be more African American, African and Hispanic/Latino attendees coming to the meeting than in years past. In addition, this meeting attracted many participants from outside the U.S. Student participation continues to be hallmark of the spirit of free exchange and cooperation characteristic of the maize genetics community. With the generous support provided by DOE, USDA NSF, and corporate/private donors, organizers were

    20. Office of Cancer Genomics |

      Cancer.gov

      The mission of the NCI’s Office of Cancer Genomics (OCG) is to enhance the understanding of the molecular mechanisms of cancer, advance and accelerate genomics science and technology development, and efficiently translate the genomics data to improve cancer research, prevention, early detection, diagnosis and treatment.

    1. Annual Research Briefs, 1992

      NASA Technical Reports Server (NTRS)

      Spinks, Debra (Compiler)

      1993-01-01

      This report contains the 1992 annual progress reports of the Research Fellows and students of the Center for Turbulence Research. Considerable effort was focused on the large eddy simulation technique for computing turbulent flows. This increased activity has been inspired by the recent predictive successes of the dynamic subgrid scale modeling procedure which was introduced during the 1990 Summer Program. Several Research Fellows and students are presently engaged in both the development of subgrid scale models and their applications to complex flows. The first group of papers in this report contain the findings of these studies. They are followed by reports grouped in the general areas of modeling, turbulence physics, and turbulent reacting flows. The last contribution in this report outlines the progress made on the development of the CTR post-processing facility.

    2. Coal industry annual 1993

      SciTech Connect

      Not Available

      1994-12-06

      Coal Industry Annual 1993 replaces the publication Coal Production (DOE/FIA-0125). This report presents additional tables and expanded versions of tables previously presented in Coal Production, including production, number of mines, Productivity, employment, productive capacity, and recoverable reserves. This report also presents data on coal consumption, coal distribution, coal stocks, coal prices, coal quality, and emissions for a wide audience including the Congress, Federal and State agencies, the coal industry, and the general public. In addition, Appendix A contains a compilation of coal statistics for the major coal-producing States. This report does not include coal consumption data for nonutility Power Producers who are not in the manufacturing, agriculture, mining, construction, or commercial sectors. This consumption is estimated to be 5 million short tons in 1993.

    3. Annual energy review 1994

      NASA Astrophysics Data System (ADS)

      1995-07-01

      This 13th edition presents the Energy Information Administration's historical energy statistics. For most series, statistics are given for every year from 1949 through 1994; thus, this report is well-suited to long-term trend analyses. It covers all major energy activities, including consumption, production, trade, stocks, and prices for all major energy commodities, including fossil fuels and electricity. Statistics on renewable energy sources are also included: this year, for the first time, usage of renewables by other consumers as well as by electric utilities is included. Also new is a two-part, comprehensive presentation of data on petroleum products supplied by sector for 1949 through 1994. Data from electric utilities and nonutilities are integrated as 'electric power industry' data; nonutility power gross generation are presented for the first time. One section presents international statistics (for more detail see EIA's International Energy Annual).

    4. Uranium Industry Annual, 1992

      SciTech Connect

      Not Available

      1993-10-28

      The Uranium Industry Annual provides current statistical data on the US uranium industry for the Congress, Federal and State agencies, the uranium and electric utility industries, and the public. The feature article, ``Decommissioning of US Conventional Uranium Production Centers,`` is included. Data on uranium raw materials activities including exploration activities and expenditures, resources and reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities including domestic uranium purchases, commitments by utilities, procurement arrangements, uranium imports under purchase contracts and exports, deliveries to enrichment suppliers, inventories, secondary market activities, utility market requirements, and uranium for sale by domestic suppliers are presented in Chapter 2.

    5. Annual energy review 1994

      SciTech Connect

      1995-07-01

      This 13th edition presents the Energy Information Administration`s historical energy statistics. For most series, statistics are given for every year from 1949 through 1994; thus, this report is well-suited to long-term trend analyses. It covers all major energy activities, including consumption, production, trade, stocks, and prices for all major energy commodities, including fossil fuels and electricity. Statistics on renewable energy sources are also included: this year, for the first time, usage of renewables by other consumers as well as by electric utilities is included. Also new is a two-part, comprehensive presentation of data on petroleum products supplied by sector for 1949 through 1994. Data from electric utilities and nonutilities are integrated as ``electric power industry`` data; nonutility power gross generation are presented for the first time. One section presents international statistics (for more detail see EIA`s International Energy Annual).

    6. Petroleum marketing annual 1993

      SciTech Connect

      Not Available

      1995-01-01

      The Petroleum Marketing Annual (PMA) contains statistical data on a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the free-on-board (f.o.b.) and landed cost of imported crude oil, and the refiners acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented. For this publication, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication dates.

    7. Uranium industry annual 1996

      SciTech Connect

      1997-04-01

      The Uranium Industry Annual 1996 (UIA 1996) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing. The UIA 1996 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. Data on uranium raw materials activities for 1987 through 1996 including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2006, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, uranium imports and exports, and uranium inventories are shown in Chapter 2. A feature article, The Role of Thorium in Nuclear Energy, is included. 24 figs., 56 tabs.

    8. 1994 MCAP annual report

      SciTech Connect

      Harmony, S.C.; Boyack, B.E.

      1995-04-01

      VELCOR is an integrated, engineering-level computer code that models the progression of severe accidents in light water reactor (LWR) nuclear power plants. The entire spectrum of severe accident phenomena, including reactor coolant system and containment thermal-hydraulic response, core heatup, degradation and relocation, and fission product release and transport is treated in MELCOR in a unified framework for both boiling water reactors (BWRs) and pressurized water reactors (PWRs). Its current uses include the estimation of severe accident source terms and their sensitivities and uncertainties in a variety of applications. Independent assessment efforts have been successfully completed by the US and international MELCOR user communities. Most of these independent assessment efforts have been conducted to support the needs and fulfill the requirements of the individual user organizations. The resources required to perform an extensive set of model and integral code assessments are large. A prudent approach to fostering code development and maturation is to coordinate the individual assessment efforts of the MELCOR user community. While retaining individual control over assessment resources, each organization using the MELCOR code could work with the other users to broaden assessment coverage and minimize duplication. In recognition of these considerations, the US Nuclear Regulatory Commission (US NRC) has initiated the MELCOR Cooperative Assessment Program (MCAP), a vehicle for coordinating and standardizing the assessment practices of the various MELCOR users. In addition, the user community will have a forum to better communicate lessons learned regarding MELCOR applications, capabilities, and user guidelines and limitations and to provide a user community perspective on code development needs and priorities. This second Annual Report builds on the foundation laid with the first Annual Report.

    9. The Annual North American Dendroecological Fieldweek: A workweek in applied tree-ring research

      SciTech Connect

      Brown, P.M.; Krusic, P.J.

      1995-12-31

      Trees record many events or processes that influence annual growth patterns. Dendrochronology is concerned with how environment and physiology affect tree growth as recorded within tree rings. The most basic principle of dendrochronology is that of crossdating, in which calendrical years are assigned to individual rings within a tree. Once crossdated, each ring is then a reflection of the climate or other environmental conditions that influenced that tree for that year. The Annual North American Dendroecological Fieldweek is a workweek in applied tree-ring research, designed to give both beginners to the discipline an introduction to its basic methodology and applications and more experienced users a change to work with and learn from others in the field in an informal group setting. The Fieldweek has had an outstanding history to date, with almost 250 participants in the five Fieldweeks from 1990 to 1994. The 6th Fieldweek is scheduled for 30 June to 8 July, 1995, at the Kananaskis Field Station in the Canadian Rockies near Calgary, Alberta.

    10. Annual Energy Outlook Retrospective Review

      EIA Publications

      2015-01-01

      The Annual Energy Outlook Retrospective Review provides a yearly comparison between realized energy outcomes and the Reference case projections included in previous Annual Energy Outlooks (AEO) beginning with 1982. This edition of the report adds the AEO 2012 projections and updates the historical data to incorporate the latest data revisions.

    11. Economic evaluation of genomic breeding programs.

      PubMed

      König, S; Simianer, H; Willam, A

      2009-01-01

      daughter records. Evaluation of levels of annual genetic gain for individual traits revealed the same potential for low heritable traits (h(2) = 0.05) compared with moderate heritable traits (h(2) = 0.30), preconditioning highly accurate genomic indices of 0.90. The final economic success of genomic breeding programs strongly depends on the complete abdication of any forms of progeny testing to reduce costs and generation intervals, but such a strategy implies the willingness of the participating milk producers.

    12. The Bluejay genome browser.

      PubMed

      Soh, Jung; Gordon, Paul M K; Sensen, Christoph W

      2012-03-01

      The Bluejay genome browser is a stand-alone visualization tool for the multi-scale viewing of annotated genomes and other genomic elements. Bluejay allows users to customize display features to suit their needs, and produces publication-quality graphics. Bluejay provides a multitude of ways to interrelate biological data at the genome scale. Users can load gene expression data into a genome display for expression visualization in context. Multiple genomes can be compared concurrently, including time series expression data, based on Gene Ontology labels. External, context-sensitive biological Web Services are linked to the displayed genomic elements ad hoc for in-depth genomic data analysis and interpretation. Users can mark multiple points of interest in a genome by creating waypoints, and exploit them for easy navigation of single or multiple genomes. Using this comprehensive visual environment, users can study a gene not just in relation to its genome, but also its transcriptome and evolutionary origins. Written in Java, Bluejay is platform-independent and is freely available from http://bluejay.ucalgary.ca.

    13. Bacterial Genome Instability

      PubMed Central

      Darmon, Elise

      2014-01-01

      SUMMARY Bacterial genomes are remarkably stable from one generation to the next but are plastic on an evolutionary time scale, substantially shaped by horizontal gene transfer, genome rearrangement, and the activities of mobile DNA elements. This implies the existence of a delicate balance between the maintenance of genome stability and the tolerance of genome instability. In this review, we describe the specialized genetic elements and the endogenous processes that contribute to genome instability. We then discuss the consequences of genome instability at the physiological level, where cells have harnessed instability to mediate phase and antigenic variation, and at the evolutionary level, where horizontal gene transfer has played an important role. Indeed, this ability to share DNA sequences has played a major part in the evolution of life on Earth. The evolutionary plasticity of bacterial genomes, coupled with the vast numbers of bacteria on the planet, substantially limits our ability to control disease. PMID:24600039

    14. UCSC genome browser tutorial.

      PubMed

      Zweig, Ann S; Karolchik, Donna; Kuhn, Robert M; Haussler, David; Kent, W James

      2008-08-01

      The University of California Santa Cruz (UCSC) Genome Bioinformatics website consists of a suite of free, open-source, on-line tools that can be used to browse, analyze, and query genomic data. These tools are available to anyone who has an Internet browser and an interest in genomics. The website provides a quick and easy-to-use visual display of genomic data. It places annotation tracks beneath genome coordinate positions, allowing rapid visual correlation of different types of information. Many of the annotation tracks are submitted by scientists worldwide; the others are computed by the UCSC Genome Bioinformatics group from publicly available sequence data. It also allows users to upload and display their own experimental results or annotation sets by creating a custom track. The suite of tools, downloadable data files, and links to documentation and other information can be found at http://genome.ucsc.edu/.

    15. Enabling responsible public genomics.

      PubMed

      Conley, John M; Doerr, Adam K; Vorhaus, Daniel B

      2010-01-01

      As scientific understandings of genetics advance, researchers require increasingly rich datasets that combine genomic data from large numbers of individuals with medical and other personal information. Linking individuals' genetic data and personal information precludes anonymity and produces medically significant information--a result not contemplated by the established legal and ethical conventions governing human genomic research. To pursue the next generation of human genomic research and commerce in a responsible fashion, scientists, lawyers, and regulators must address substantial new issues, including researchers' duties with respect to clinically significant data, the challenges to privacy presented by genomic data, the boundary between genomic research and commerce, and the practice of medicine. This Article presents a new model for understanding and addressing these new challenges--a "public genomics" premised on the idea that ethically, legally, and socially responsible genomics research requires openness, not privacy, as its organizing principle. Responsible public genomics combines the data contributed by informed and fully consenting information altruists and the research potential of rich datasets in a genomic commons that is freely and globally available. This Article examines the risks and benefits of this public genomics model in the context of an ambitious genetic research project currently under way--the Personal Genome Project. This Article also (i) demonstrates that large-scale genomic projects are desirable, (ii) evaluates the risks and challenges presented by public genomics research, and (iii) determines that the current legal and regulatory regimes restrict beneficial and responsible scientific inquiry while failing to adequately protect participants. The Article concludes by proposing a modified normative and legal framework that embraces and enables a future of responsible public genomics.

    16. Whole-exome/genome sequencing and genomics.

      PubMed

      Grody, Wayne W; Thompson, Barry H; Hudgins, Louanne

      2013-12-01

      As medical genetics has progressed from a descriptive entity to one focused on the functional relationship between genes and clinical disorders, emphasis has been placed on genomics. Genomics, a subelement of genetics, is the study of the genome, the sum total of all the genes of an organism. The human genome, which is contained in the 23 pairs of nuclear chromosomes and in the mitochondrial DNA of each cell, comprises >6 billion nucleotides of genetic code. There are some 23,000 protein-coding genes, a surprisingly small fraction of the total genetic material, with the remainder composed of noncoding DNA, regulatory sequences, and introns. The Human Genome Project, launched in 1990, produced a draft of the genome in 2001 and then a finished sequence in 2003, on the 50th anniversary of the initial publication of Watson and Crick's paper on the double-helical structure of DNA. Since then, this mass of genetic information has been translated at an ever-increasing pace into useable knowledge applicable to clinical medicine. The recent advent of massively parallel DNA sequencing (also known as shotgun, high-throughput, and next-generation sequencing) has brought whole-genome analysis into the clinic for the first time, and most of the current applications are directed at children with congenital conditions that are undiagnosable by using standard genetic tests for single-gene disorders. Thus, pediatricians must become familiar with this technology, what it can and cannot offer, and its technical and ethical challenges. Here, we address the concepts of human genomic analysis and its clinical applicability for primary care providers.

    17. A report from the Sixth International Mouse Genome Conference

      SciTech Connect

      Brown, S.

      1992-12-31

      The Sixth Annual Mouse Genome Conference was held in October, 1992 at Buffalo, USA. The mouse is one of the primary model organisms in the Human Genome Project. Through the use of gene targeting studies the mouse has become a powerful biological model for the study of gene function and, in addition, the comparison of the many homologous mutations identified in human and mouse have widened our understanding of the biology of these two organisms. A primary goal in the mouse genome program has been to create a genetic map of STSs of high resolution (<1cM) that would form the basis for the physical mapping of the whole mouse genome. Buffalo saw substantial new progress towards the goal of a very high density genetic map and the beginnings of substantive efforts towards physical mapping in chromosome regions with a high density of genetic markers.

    18. An introduction to genes, genomes and disease.

      PubMed

      Hall, Peter A; Reis-Filho, Jorge S; Tomlinson, Ian Pm; Poulsom, Richard

      2010-01-01

      The human and other genome projects and subsequent resequencing programmes have provided new perspectives on the nature of the gene and how genes function. Understanding the complexity of the eukaryotic nucleus and the diversity of genetic regulatory mechanisms, including the role of non-coding RNAs, translational control mechanisms and the extraordinary prevalence of splicing, will be central to understanding how genes function, as will the recognition of gene dosage issues. This introduction to the 2010 Annual Review Issue, Genes, Genomes and Disease, provides overviews of these areas and then considers their relevance to a range of human diseases, including cardiovascular and renal disease, neural tube defects and cancer. The p53 gene is considered as an example of a massively regulated gene and the genetic perturbations in cancer are considered in a historical perspective. High-throughput genomic and transcriptomic methods have led to a paradigm shift in the way cancers are perceived and have changed the way translational research is performed. The progress in our understanding of chromosomal rearrangements in cancer, once believed to be incredibly rare events in epithelial malignancies, is discussed. The identification of low-penetrance cancer susceptibility genes through genome-wide association studies and their implications are reviewed. The contribution and limitations of expression profiling are discussed. In the last series of reviews, future challenges are addressed: the promise of synthetic lethality strategies in cancer therapy, a case for 'systems' approaches to genetic networks and the potential of single molecule genetic technologies. Finally, the question 'Does massively parallel DNA resequencing signify the end of histopathology as we know it?' is posed. Readers should find that the 2010 Annual Review Issue is an invaluable resource on contemporary genetics and its applications to understanding disease.

    19. 2014 HPC Annual Report

      SciTech Connect

      Jennings, Barbara

      2014-10-01

      Our commitment is to support you through delivery of an IT environment that provides mission value by transforming the way you use, protect, and access information. We approach this through technical innovation, risk management, and relationships with our workforce, Laboratories leadership, and policy makers nationwide. This second edition of our HPC Annual Report continues our commitment to communicate the details and impact of Sandia’s large-scale computing resources that support the programs associated with our diverse mission areas. A key tenet to our approach is to work with our mission partners to understand and anticipate their requirements and formulate an investment strategy that is aligned with those Laboratories priorities. In doing this, our investments include not only expanding the resources available for scientific computing and modeling and simulation, but also acquiring large-scale systems for data analytics, cloud computing, and Emulytics. We are also investigating new computer architectures in our advanced systems test bed to guide future platform designs and prepare for changes in our code development models. Our initial investments in large-scale institutional platforms that are optimized for Informatics and Emulytics work are serving a diverse customer base. We anticipate continued growth and expansion of these resources in the coming years as the use of these analytic techniques expands across our mission space. If your program could benefit from an investment in innovative systems, please work through your Program Management Unit ’s Mission Computing Council representatives to engage our teams.

    20. Annual energy review 1992

      SciTech Connect

      Not Available

      1993-06-29

      This eleventh edition of the Annual Energy Review (AER) presents the Energy Information Administration`s historical energy statistics. For most series, statistics are given for every year from 1949 through 1992. Because coverage spans four decades, the statistics in this report are well-suited to tong-term trend analyses. The AER is comprehensive. It covers all major energy activities, including consumption, production, trade, stocks, and prices, all major energy commodities, including fossil fuels and electricity. The AER also presents statistics on some renewable energy sources. For the most part, fuel-specific data are expressed in physical units such as barrels, cubic feet, and short tons. The integrated summary data in Section 1 are expressed in Btu. The Btu values are calculated using the conversion factors in Appendix A. Statistics expressed in Btu are valuable in that they allow for comparisons among different fuels and for the calculation of in the integrated summary statistics such as US consumption of Energy. The AER emphasizes domestic energy statistics.

    1. Annual Research Briefs: 1995

      NASA Technical Reports Server (NTRS)

      1995-01-01

      This report contains the 1995 annual progress reports of the Research Fellows and students of the Center for Turbulence Research (CTR). In 1995 CTR continued its concentration on the development and application of large-eddy simulation to complex flows, development of novel modeling concepts for engineering computations in the Reynolds averaged framework, and turbulent combustion. In large-eddy simulation, a number of numerical and experimental issues have surfaced which are being addressed. The first group of reports in this volume are on large-eddy simulation. A key finding in this area was the revelation of possibly significant numerical errors that may overwhelm the effects of the subgrid-scale model. We also commissioned a new experiment to support the LES validation studies. The remaining articles in this report are concerned with Reynolds averaged modeling, studies of turbulence physics and flow generated sound, combustion, and simulation techniques. Fundamental studies of turbulent combustion using direct numerical simulations which started at CTR will continue to be emphasized. These studies and their counterparts carried out during the summer programs have had a noticeable impact on combustion research world wide.

    2. Annual Energy Review 2000

      SciTech Connect

      Seiferlein, Katherine E.

      2001-08-01

      The Annual Energy Review (AER) presents the Energy Information Administration’s historical energy statistics. For many series, statistics are given for every year from 1949 through 2000. The statistics, expressed in either physical units or British thermal units, cover all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels, electricity, and renewable energy sources. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the Energy Information Administration under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

    3. Annual Energy Review 2002

      SciTech Connect

      Seiferlein, Katherine E.

      2003-10-01

      The Annual Energy Review (AER) presents the Energy Information Administration’s historical energy statistics. For many series, statistics are given for every year from 1949 through 2002. The statistics, expressed in either physical units or British thermal units, cover all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels, electricity, and renewable energy sources. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the Energy Information Administration (EIA) under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications. Related Publication: Readers of the AER may also be interested in EIA’s Monthly Energy Review, which presents monthly updates of many of the data in the AER. Contact our National Energy Information Center for more information.

    4. 2007 LDRD ANNUAL REPORT

      SciTech Connect

      French, T

      2008-12-16

      I am pleased to present the fiscal year 2007 Laboratory Directed Research and Development (LDRD) annual report. This represents the first year that SRNL has been eligible for LDRD participation and our results to date demonstrate we are off to an excellent start. SRNL became a National Laboratory in 2004, and was designated the 'Corporate Laboratory' for the DOE Office of Environmental Management (EM) in 2006. As you will see, we have made great progress since these designations. The LDRD program is one of the tools SRNL is using to enable achievement of our strategic goals for the DOE. The LDRD program allows the laboratory to blend a strong basic science component into our applied technical portfolio. This blending of science with applied technology provides opportunities for our scientists to strengthen our capabilities and delivery. The LDRD program is vital to help SRNL attract and retain leading scientists and engineers who will help build SRNL's future and achieve DOE mission objectives. This program has stimulated our research staff creativity, while realizing benefits from their participation. This investment will yield long term dividends to the DOE in its Environmental Management, Energy, and National Security missions.

    5. Annual Energy Review 1997

      SciTech Connect

      Seiferlein, Katherine E.

      1998-07-01

      The Annual Energy Review (AER) presents the Energy Information Administration’s historical energy statistics. For many series, statistics are given for every year from 1949 through 1997. The statistics, expressed in either physical units or British thermal units, cover all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels, electricity, and renewable energy sources. Publication of this report is in keeping with responsibilities given to the Energy Information Administration (EIA) in Public Law 95–91 (Department of Energy Organization Act), which states, in part, in Section 205(a)(2) that: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

    6. Agaricus bisporus genome sequence: a commentary.

      PubMed

      Kerrigan, Richard W; Challen, Michael P; Burton, Kerry S

      2013-06-01

      The genomes of two isolates of Agaricus bisporus have been sequenced recently. This soil-inhabiting fungus has a wide geographical distribution in nature and it is also cultivated in an industrialized indoor process ($4.7bn annual worldwide value) to produce edible mushrooms. Previously this lignocellulosic fungus has resisted precise econutritional classification, i.e. into white- or brown-rot decomposers. The generation of the genome sequence and transcriptomic analyses has revealed a new classification, 'humicolous', for species adapted to grow in humic-rich, partially decomposed leaf material. The Agaricus biporus genomes contain a collection of polysaccharide and lignin-degrading genes and more interestingly an expanded number of genes (relative to other lignocellulosic fungi) that enhance degradation of lignin derivatives, i.e. heme-thiolate peroxidases and β-etherases. A motif that is hypothesized to be a promoter element in the humicolous adaptation suite is present in a large number of genes specifically up-regulated when the mycelium is grown on humic-rich substrate. The genome sequence of A. bisporus offers a platform to explore fungal biology in carbon-rich soil environments and terrestrial cycling of carbon, nitrogen, phosphorus and potassium.

    7. 2009 Annual Report TATRC

      DTIC Science & Technology

      2009-01-01

      Samueli Institute ������������������������������������������������������������������������������������������������������113 Vision Research Program...through a common problem set (e�g�, cancer genomics, NETPR, Samueli Insititute, vision research)� In each of the examples we have chosen to highlight...TATRC we can make their lives better, then our mission has been successful�” Brenda Bart-Knauer, M�D� TATRC Program Manager 113 Samueli  Institute

    8. Engineering Annual Summary 1996

      SciTech Connect

      Dimolitsas, S.

      1997-04-30

      Fiscal year 1996 has been a year of significant change for the Lawrence Livermore National Laboratory (LLNL) in general and for Engineering in particular. Among these changes, the Laboratory`s national security mission was better defined, the stockpile stewardship program objectives became crisper, LLNL`s investment in high-performance computing was re-emphasized with the procurement of a $100 million supercomputer for the Laboratory`s Accelerated Strategic Computing Initiative (ASCI) program, two major Laser programs (the National Ignition Facility and Atomic Vapor Laser Isotope Separation) expanded significantly, and DOE`s human genome efforts moved to the next phase of development. In the area of business operations, LLNL`s Cost Cutting Initiative Program (CCIP) was completed and the Laboratory restructured its workforce using a Voluntary Separation Incentive Program (VSIP). Engineering similarly also saw many technical and programmatic successes, as well as changes, starting with completion of its strategic plan, significant consolidation of its facilities, restructuring of its workforce, reduction of its overhead costs, substantial transfers of staff between programs, and finally my personal arrival at Livermore. This report is the first opportunity to capture some of Engineering`s FY96 activities and accomplishments in a succinct fashion, and to relate these to our strategic plan.

    9. State of cat genomics.

      PubMed

      O'Brien, Stephen J; Johnson, Warren; Driscoll, Carlos; Pontius, Joan; Pecon-Slattery, Jill; Menotti-Raymond, Marilyn

      2008-06-01

      Our knowledge of cat family biology was recently expanded to include a genomics perspective with the completion of a draft whole genome sequence of an Abyssinian cat. The utility of the new genome information has been demonstrated by applications ranging from disease gene discovery and comparative genomics to species conservation. Patterns of genomic organization among cats and inbred domestic cat breeds have illuminated our view of domestication, revealing linkage disequilibrium tracks consequent of breed formation, defining chromosome exchanges that punctuated major lineages of mammals and suggesting ancestral continental migration events that led to 37 modern species of Felidae. We review these recent advances here. As the genome resources develop, the cat is poised to make a major contribution to many areas in genetics and biology.

    10. FY 2015 Annual Performance Report

      EPA Pesticide Factsheets

      Presents detailed performance results, as measured against the targets established in EPA’s FY 2015 Annual Plan and Budget. The Executive Overview section analyzes key performance outcomes and links to FY 2015 program evaluations.

    11. Annual Performance Report - FY 2011

      EPA Pesticide Factsheets

      This report summarizes OIG activity, performance, results, and challenges, and provides a financial accounting of resources for fiscal year (FY) 2011 compared to our FY 2011 annual performance targets.

    12. LLNL NESHAPs 2004 Annual Report

      SciTech Connect

      Harrach, R; Gallegos, G; Peterson, R; Wilson, K; Harrach, R J; Gallegos, G M; Peterson, S R; Wilson, K R

      2005-06-27

      This annual report is prepared pursuant to the National Emission Standards for Hazardous Air Pollutants (NESHAPs; Title 40 Code of Federal Regulations [CFR] Part 61, Subpart H). Subpart H governs radionuclide emissions to air from Department of Energy (DOE) facilities.

    13. Annual Research Briefs

      NASA Technical Reports Server (NTRS)

      Spinks, Debra (Compiler)

      1997-01-01

      This report contains the 1997 annual progress reports of the research fellows and students supported by the Center for Turbulence Research (CTR). Titles include: Invariant modeling in large-eddy simulation of turbulence; Validation of large-eddy simulation in a plain asymmetric diffuser; Progress in large-eddy simulation of trailing-edge turbulence and aeronautics; Resolution requirements in large-eddy simulations of shear flows; A general theory of discrete filtering for LES in complex geometry; On the use of discrete filters for large eddy simulation; Wall models in large eddy simulation of separated flow; Perspectives for ensemble average LES; Anisotropic grid-based formulas for subgrid-scale models; Some modeling requirements for wall models in large eddy simulation; Numerical simulation of 3D turbulent boundary layers using the V2F model; Accurate modeling of impinging jet heat transfer; Application of turbulence models to high-lift airfoils; Advances in structure-based turbulence modeling; Incorporating realistic chemistry into direct numerical simulations of turbulent non-premixed combustion; Effects of small-scale structure on turbulent mixing; Turbulent premixed combustion in the laminar flamelet and the thin reaction zone regime; Large eddy simulation of combustion instabilities in turbulent premixed burners; On the generation of vorticity at a free-surface; Active control of turbulent channel flow; A generalized framework for robust control in fluid mechanics; Combined immersed-boundary/B-spline methods for simulations of flow in complex geometries; and DNS of shock boundary-layer interaction - preliminary results for compression ramp flow.

    14. Annual energy review 2003

      SciTech Connect

      Seiferlein, Katherin E.

      2004-09-30

      The Annual Energy Review 2003 is a statistical history of energy activities in the United States in modern times. Data are presented for all major forms of energy by production (extraction of energy from the earth, water, and other parts of the environment), consumption by end-user sector, trade with other nations, storage changes, and pricing. Much of the data provided covers the fossil fuels—coal, petroleum, and natural gas. Fossil fuels are nature’s batteries; they have stored the sun’s energy over millennia past. It is primarily that captured energy that we are drawing on today to fuel the activities of the modern economy. Data in this report measure the extraordinary expansion of our use of fossil fuels from 29 quadrillion British thermal units (Btu) in 1949 to 84 quadrillion Btu in 2003. In recent years, fossil fuels accounted for 86 percent of all energy consumed in the United States. This report also records the development of an entirely new energy industry—the nuclear electric power industry. The industry got its start in this country in 1957 when the Shippingport, Pennsylvania, nuclear electric power plant came on line. Since that time, the industry has grown to account for 20 percent of our electrical output and 8 percent of all energy used in the country. Renewable energy is a third major category of energy reported in this volume. Unlike fossil fuels, which are finite in supply, renewable energy is essentially inexhaustible because it can be replenished. Types of energy covered in the renewable category include conventional hydroelectric power, which is power derived from falling water; wood; waste; alcohol fuels; geothermal; solar; and wind. Together, these forms of energy accounted for about 6 percent of all U.S. energy consumption in recent years.

    15. 2005 Annual Report

      SciTech Connect

      Chrzanowski, P; Walter, K

      2006-03-31

      As the cover of our ''2005 Annual Report'' highlights, Lawrence Livermore National Laboratory joined the international science community in celebrating the World Year of Physics in 2005, with special events and science outreach and education programs. Einstein's remarkable discoveries in 1905 provided an opportunity to reflect on how physics has changed the world during the last century and on the promise of future beneficial discoveries. For half of the past century, Lawrence Livermore, which was established to meet an urgent national security need, has been contributing to the advancement of science and technology in a very special way. Co-founder Ernest O. Lawrence was the leading proponent in his generation of large-scale, multidisciplinary science and technology teams. That's Livermore's distinctive heritage and our continuing approach as a national laboratory managed and operated by the University of California for the Department of Energy's National Nuclear Security Administration (DOE/NNSA). We focus on important problems that affect our nation's security and seek breakthrough advances in science and technology to achieve mission goals. An event in 2005 exemplifies our focus on science and technology advances in support of mission goals. In October, distinguished visitors came to Livermore to celebrate the tenth anniversary of the Accelerated Strategic Computing Initiative (now called the Advanced Simulation and Computing Program, or ASC). ASC was launched in 1995 by DOE/NNSA to achieve a million-fold increase in computing power in a decade. The goal was motivated by the need to simulate the three-dimensional performance of a nuclear weapon in sufficient resolution and with the appropriately detailed physics models included. This mission-driven goal is a key part of fulfilling Livermore's foremost responsibility to ensure that the nuclear weapons in the nation's smaller 21st-century stockpile remain safe, reliable, and secure.

    16. Annual energy review 1997

      SciTech Connect

      1998-07-01

      The Annual Energy Review (AER) is a historical data report that tells many stories. It describes, in numbers, the changes that have occurred in US energy markets since the midpoint of the 20th century. In many cases, those markets differ vastly from those of a half-century ago. By studying the graphs and data tables presented in this report, readers can learn about past energy supply and usage in the United States and gain an understanding of the issues in energy and the environment now before use. While most of this year`s report content is similar to last year`s, there are some noteworthy developments. Table 1.1 has been restructured into more summarized groupings -- fossil fuels, nuclear electric power, and renewable energy -- to aid analysts in their examination of the basic trends in those broad categories. Readers` attention is also directed to the electricity section, where considerable reformatting of the tables and graphs has been carried out to help clarify past and recent trends in the electric power industry as it enters a period of radical restructuring. Table 9.1, which summarizes US nuclear generating units, has been redeveloped to cover the entire history of the industry in this country and to provide categories relevant in assessing the future of the industry, such as the numbers of ordered generating units that have been canceled and those that were built and later shut down. In general, the AER emphasizes domestic energy statistics. Sections 1 through 10 and Section 12 are devoted mostly to US data; Section 11 reports on international statistics and world totals. 140 figs., 141 tabs.

    17. Querying genomic databases

      SciTech Connect

      Baehr, A.; Hagstrom, R.; Joerg, D.; Overbeek, R.

      1991-09-01

      A natural-language interface has been developed that retrieves genomic information by using a simple subset of English. The interface spares the biologist from the task of learning database-specific query languages and computer programming. Currently, the interface deals with the E. coli genome. It can, however, be readily extended and shows promise as a means of easy access to other sequenced genomic databases as well.

    18. [Landscape and ecological genomics].

      PubMed

      Tetushkin, E Ia

      2013-10-01

      Landscape genomics is the modern version of landscape genetics, a discipline that arose approximately 10 years ago as a combination of population genetics, landscape ecology, and spatial statistics. It studies the effects of environmental variables on gene flow and other microevolutionary processes that determine genetic connectivity and variations in populations. In contrast to population genetics, it operates at the level of individual specimens rather than at the level of population samples. Another important difference between landscape genetics and genomics and population genetics is that, in the former, the analysis of gene flow and local adaptations takes quantitative account of landforms and features of the matrix, i.e., hostile spaces that separate species habitats. Landscape genomics is a part of population ecogenomics, which, along with community genomics, is a major part of ecological genomics. One of the principal purposes of landscape genomics is the identification and differentiation of various genome-wide and locus-specific effects. The approaches and computation tools developed for combined analysis of genomic and landscape variables make it possible to detect adaptation-related genome fragments, which facilitates the planning of conservation efforts and the prediction of species' fate in response to expected changes in the environment.

    19. Genomics of Clostridium tetani.

      PubMed

      Brüggemann, Holger; Brzuszkiewicz, Elzbieta; Chapeton-Montes, Diana; Plourde, Lucile; Speck, Denis; Popoff, Michel R

      2015-05-01

      Genomic information about Clostridium tetani, the causative agent of the tetanus disease, is scarce. The genome of strain E88, a strain used in vaccine production, was sequenced about 10 years ago. One additional genome (strain 12124569) has recently been released. Here we report three new genomes of C. tetani and describe major differences among all five C. tetani genomes. They all harbor tetanus-toxin-encoding plasmids that contain highly conserved genes for TeNT (tetanus toxin), TetR (transcriptional regulator of TeNT) and ColT (collagenase), but substantially differ in other plasmid regions. The chromosomes share a large core genome that contains about 85% of all genes of a given chromosome. The non-core chromosome comprises mainly prophage-like genomic regions and genes encoding environmental interaction and defense functions (e.g. surface proteins, restriction-modification systems, toxin-antitoxin systems, CRISPR/Cas systems) and other fitness functions (e.g. transport systems, metabolic activities). This new genome information will help to assess the level of genome plasticity of the species C. tetani and provide the basis for detailed comparative studies.

    20. Between Two Fern Genomes

      PubMed Central

      2014-01-01

      Ferns are the only major lineage of vascular plants not represented by a sequenced nuclear genome. This lack of genome sequence information significantly impedes our ability to understand and reconstruct genome evolution not only in ferns, but across all land plants. Azolla and Ceratopteris are ideal and complementary candidates to be the first ferns to have their nuclear genomes sequenced. They differ dramatically in genome size, life history, and habit, and thus represent the immense diversity of extant ferns. Together, this pair of genomes will facilitate myriad large-scale comparative analyses across ferns and all land plants. Here we review the unique biological characteristics of ferns and describe a number of outstanding questions in plant biology that will benefit from the addition of ferns to the set of taxa with sequenced nuclear genomes. We explain why the fern clade is pivotal for understanding genome evolution across land plants, and we provide a rationale for how knowledge of fern genomes will enable progress in research beyond the ferns themselves. PMID:25324969

    1. Between two fern genomes.

      PubMed

      Sessa, Emily B; Banks, Jo Ann; Barker, Michael S; Der, Joshua P; Duffy, Aaron M; Graham, Sean W; Hasebe, Mitsuyasu; Langdale, Jane; Li, Fay-Wei; Marchant, D Blaine; Pryer, Kathleen M; Rothfels, Carl J; Roux, Stanley J; Salmi, Mari L; Sigel, Erin M; Soltis, Douglas E; Soltis, Pamela S; Stevenson, Dennis W; Wolf, Paul G

      2014-01-01

      Ferns are the only major lineage of vascular plants not represented by a sequenced nuclear genome. This lack of genome sequence information significantly impedes our ability to understand and reconstruct genome evolution not only in ferns, but across all land plants. Azolla and Ceratopteris are ideal and complementary candidates to be the first ferns to have their nuclear genomes sequenced. They differ dramatically in genome size, life history, and habit, and thus represent the immense diversity of extant ferns. Together, this pair of genomes will facilitate myriad large-scale comparative analyses across ferns and all land plants. Here we review the unique biological characteristics of ferns and describe a number of outstanding questions in plant biology that will benefit from the addition of ferns to the set of taxa with sequenced nuclear genomes. We explain why the fern clade is pivotal for understanding genome evolution across land plants, and we provide a rationale for how knowledge of fern genomes will enable progress in research beyond the ferns themselves.

    2. Fungal Genomics Program

      SciTech Connect

      Grigoriev, Igor

      2012-03-12

      The JGI Fungal Genomics Program aims to scale up sequencing and analysis of fungal genomes to explore the diversity of fungi important for energy and the environment, and to promote functional studies on a system level. Combining new sequencing technologies and comparative genomics tools, JGI is now leading the world in fungal genome sequencing and analysis. Over 120 sequenced fungal genomes with analytical tools are available via MycoCosm (www.jgi.doe.gov/fungi), a web-portal for fungal biologists. Our model of interacting with user communities, unique among other sequencing centers, helps organize these communities, improves genome annotation and analysis work, and facilitates new larger-scale genomic projects. This resulted in 20 high-profile papers published in 2011 alone and contributing to the Genomics Encyclopedia of Fungi, which targets fungi related to plant health (symbionts, pathogens, and biocontrol agents) and biorefinery processes (cellulose degradation, sugar fermentation, industrial hosts). Our next grand challenges include larger scale exploration of fungal diversity (1000 fungal genomes), developing molecular tools for DOE-relevant model organisms, and analysis of complex systems and metagenomes.

    3. MIPS plant genome information resources.

      PubMed

      Spannagl, Manuel; Haberer, Georg; Ernst, Rebecca; Schoof, Heiko; Mayer, Klaus F X

      2007-01-01

      The Munich Institute for Protein Sequences (MIPS) has been involved in maintaining plant genome databases since the Arabidopsis thaliana genome project. Genome databases and analysis resources have focused on individual genomes and aim to provide flexible and maintainable data sets for model plant genomes as a backbone against which experimental data, for example from high-throughput functional genomics, can be organized and evaluated. In addition, model genomes also form a scaffold for comparative genomics, and much can be learned from genome-wide evolutionary studies.

    4. Structure and Functional Studies on Dengue-2 Virus Genome

      DTIC Science & Technology

      1986-03-01

      AD_ _ _ Lfl oSTRUCTURE AND FUNCTIONAL STUDIES ON DENGUE -2 VIRUS GENOME 0Annual Report Radha Krishnan Padmanabhan, Ph.D. March 1, 1986 Supported by...Studies on Dengue -2 Virus Genome 12 PERSONAL AUTHOR(S) Radha Krishnan Padmanabhan 13a TYPE OF REPORT 1 3b TIME COVERED 14 DATE OF REPORT (Year, Month, Day...analysis of these clones totalling 06 01 14,586 nucleotides: Deduced amino acid sequences of dengue virI 19 ABSTRACT (Continue on reverse of

    5. Home - The Cancer Genome Atlas - Cancer Genome - TCGA

      Cancer.gov

      The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing.

    6. 77 FR 64463 - Annual Retail Trade Survey

      Federal Register 2010, 2011, 2012, 2013, 2014

      2012-10-22

      ..., the Census Bureau will collect data covering annual sales, annual e- commerce sales, year-end..., accounts receivables, and, for selected industries, merchandise line sales, and percent of e-commerce sales..., annual sales, annual e-commerce sales, purchases, total and detailed operating expenses,...

    7. 78 FR 64912 - Annual Retail Trade Survey

      Federal Register 2010, 2011, 2012, 2013, 2014

      2013-10-30

      ... survey, the Census Bureau will collect data covering annual sales, annual e-commerce sales, year-end... annual sales, annual e-commerce sales, year-end inventories held inside and outside the United States... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF...

    8. 75 FR 63804 - Annual Retail Trade Survey

      Federal Register 2010, 2011, 2012, 2013, 2014

      2010-10-18

      ... survey, the Census Bureau will collect data covering annual sales, annual e-commerce sales, year-end... percent of e-commerce sales to customers located outside the United States. These data are collected to... classification basis, annual sales, annual e-commerce sales, purchases, total operating expenses,...

    9. 22 CFR 62.15 - Annual reports.

      Code of Federal Regulations, 2010 CFR

      2010-04-01

      ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Annual reports. 62.15 Section 62.15 Foreign... § 62.15 Annual reports. Sponsors shall submit an annual report to the Department of State. An... desire for redesignation, pursuant to § 62.7, by marking the appropriate box on their annual report....

    10. 7 CFR 3400.23 - Annual reports.

      Code of Federal Regulations, 2010 CFR

      2010-01-01

      ... 7 Agriculture 15 2010-01-01 2010-01-01 false Annual reports. 3400.23 Section 3400.23 Agriculture... SERVICE, DEPARTMENT OF AGRICULTURE SPECIAL RESEARCH GRANTS PROGRAM Annual Reports § 3400.23 Annual reports. (a) Reporting requirement. The recipient shall submit an annual report describing the results of...

    11. 25 CFR 122.9 - Annual report.

      Code of Federal Regulations, 2010 CFR

      2010-04-01

      ... 25 Indians 1 2010-04-01 2010-04-01 false Annual report. 122.9 Section 122.9 Indians BUREAU OF... EDUCATION § 122.9 Annual report. The Osage Tribal Education Committee shall submit an annual report on OMB approved Form 1076-0106, Higher Education Annual Report, to the Assistant Secretary or his/her...

    12. 16 CFR 1018.42 - Annual report.

      Code of Federal Regulations, 2010 CFR

      2010-01-01

      ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Annual report. 1018.42 Section 1018.42... Reports and Audits § 1018.42 Annual report. (a) The Advisory Committee Management Officer shall prepare an annual report on the Commission's advisory committees for inclusion in the President's annual report...

    13. 49 CFR 195.49 - Annual report.

      Code of Federal Regulations, 2010 CFR

      2010-10-01

      ... 49 Transportation 3 2010-10-01 2010-10-01 false Annual report. 195.49 Section 195.49... PIPELINE Annual, Accident, and Safety-Related Condition Reporting § 195.49 Annual report. Beginning no... dioxide pipelines. Operators are encouraged, but not required, to file an annual report by June 15,...

    14. 21 CFR 1002.13 - Annual reports.

      Code of Federal Regulations, 2010 CFR

      2010-04-01

      ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Annual reports. 1002.13 Section 1002.13 Food and... Annual reports. (a) Every manufacturer of products requiring an annual report as specified in table 1 of § 1002.1 shall submit an annual report summarizing the contents of the records required to be...

    15. 14 CFR 120.119 - Annual reports.

      Code of Federal Regulations, 2010 CFR

      2010-01-01

      ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Annual reports. 120.119 Section 120.119... Drug Testing Program Requirements § 120.119 Annual reports. (a) Annual reports of testing results must... holder shall submit an annual report each year. (2) Each entity conducting a drug testing program...

    16. 7 CFR 900.355 - Annual reporting.

      Code of Federal Regulations, 2010 CFR

      2010-01-01

      ... 7 Agriculture 8 2010-01-01 2010-01-01 false Annual reporting. 900.355 Section 900.355 Agriculture... Determining the Qualification of Cooperative Milk Marketing Associations § 900.355 Annual reporting... qualified pursuant to the Act is required to file an annual report after its annual meeting has been...

    17. Stockholder Reactions to Corporate Annual Reports.

      ERIC Educational Resources Information Center

      Means, Thomas Lee

      A study was conducted to assess the extent to which (1) stockholders consider corporate annual reports to be informative and useful, (2) they actually read annual reports, (3) they consider annual reports to be impressive, and (4) they are motivated by the annual report to invest further in corporations in which they already own stock. After the…

    18. NERI 2004 Annual Report

      SciTech Connect

      2004-01-01

      The United States Department of Energy (DOE) created the Nuclear Energy Research Initiative (NERI) in Fiscal Year (FY) 1999 in response to recommendations provided by the President's Committee of Advisors on Science and Technology. The purpose of NERI is to sponsor research and development (R&D) in the nuclear energy sciences to address the principal barriers to the future use of nuclear energy in the United States. NERI is helping to preserve the nuclear science and engineering infrastructure within the Nation's universities, laboratories, and industry, and is advancing the development of nuclear energy technology, enabling the United States to maintain a competitive position in nuclear science and technology. Research under this initiative also addresses issues associated with the maintenance of existing U.S. nuclear plants. The NERI program is managed and funded by DOE's Office of Nuclear Energy, Science and Technology. ''The Nuclear Energy Research Initiative 2004 Annual Report'' serves to inform interested parties of progress made in NERI on a programmatic level as well as research progress made on individual NERI projects. Section 2 of this report provides background on the creation and implementation of NERI and on the focus areas for NERI research. Section 3 provides a discussion on NERI's mission, goals and objectives, and work scope. Section 4 highlights the major accomplishments of the NERI projects and provides brief summaries of the NERI research efforts that were completed in 2004. Section 5 provides a discussion on the impact NERI has had on U.S. university nuclear programs. Sections 6 through 8 provide project status reports by research area for each of the fiscal year (FY) 2001 and 2002 projects that were active in FY 2004. Research objectives, progress made over the last year, and activities planned for the next year are described for each project. Sections 9 through 11 present each of the newly awarded 2005 NERI projects in their corresponding

    19. Revisiting the sequencing of the first tree genome: Populus trichocarpa.

      PubMed

      Wullschleger, Stan D; Weston, D J; DiFazio, S P; Tuskan, G A

      2013-04-01

      Ten years ago, it was announced that the Joint Genome Institute with funds provided by the Department of Energy, Office of Science, Biological and Environmental Research would sequence the black cottonwood (Populus trichocarpa Torr. & Gray) genome. This landmark decision was the culmination of work by the forest science community to develop Populus as a model system. Since its public release in late 2006, the availability of the Populus genome has spawned research in plant biology, morphology, genetics and ecology. Here we address how the tree physiologist has used this resource. More specifically, we revisit our earlier contention that the rewards of sequencing the Populus genome would depend on how quickly scientists working with woody perennials could adopt molecular approaches to investigate the mechanistic underpinnings of basic physiological processes. Several examples illustrate the integration of functional and comparative genomics into the forest sciences, especially in areas that target improved understanding of the developmental differences between woody perennials and herbaceous annuals (e.g., phase transitions). Sequencing the Populus genome and the availability of genetic and genomic resources has also been instrumental in identifying candidate genes that underlie physiological and morphological traits of interest. Genome-enabled research has advanced our understanding of how phenotype and genotype are related and provided insights into the genetic mechanisms whereby woody perennials adapt to environmental stress. In the future, we anticipate that low-cost, high-throughput sequencing will continue to facilitate research in tree physiology and enhance our understanding at scales of individual organisms and populations. A challenge remains, however, as to how genomic resources, including the Populus genome, can be used to understand ecosystem function. Although examples are limited, progress in this area is encouraging and will undoubtedly improve as

    20. Genomics of Disease

      Technology Transfer Automated Retrieval System (TEKTRAN)

      This edited book represents the 23rd symposium in the Stadler Genetics Symposia series, and the general theme of this conference was "The Genomics of Disease." The 24 national and international speakers were invited to discuss their world-class research into the advances that genomics has made on c...

    1. Genetics and Genomics

      Technology Transfer Automated Retrieval System (TEKTRAN)

      Good progress is being made on genetics and genomics of sugar beet, however it is in process and the tools are now being generated and some results are being analyzed. The GABI BeetSeq project released a first draft of the sugar beet genome of KWS2320, a dihaploid (see http://bvseq.molgen.mpg.de/Gen...

    2. Automated Microbial Genome Annotation

      SciTech Connect

      Land, Miriam

      2009-05-29

      Miriam Land of the DOE Joint Genome Institute at Oak Ridge National Laboratory gives a talk on the current state and future challenges of moving toward automated microbial genome annotation at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

    3. Genomics for Weed Science

      Technology Transfer Automated Retrieval System (TEKTRAN)

      Numerous genomic-based studies have provided insight to the physiological and evolutionary processes involved in developmental and environmental processes of model plants such as arabidopsis and rice. However, far fewer efforts have been attempted to use genomic resources to study physiological and ...

    4. Unlocking the bovine genome

      Technology Transfer Automated Retrieval System (TEKTRAN)

      The draft genome sequence of cattle (Bos taurus) has now been analyzed by the Bovine Genome Sequencing and Analysis Consortium and the Bovine HapMap Consortium, which together represent an extensive collaboration involving more than 300 scientists from 25 different countries. ...

    5. Breeding-assisted genomics.

      PubMed

      Poland, Jesse

      2015-04-01

      The revolution of inexpensive sequencing has ushered in an unprecedented age of genomics. The promise of using this technology to accelerate plant breeding is being realized with a vision of genomics-assisted breeding that will lead to rapid genetic gain for expensive and difficult traits. The reality is now that robust phenotypic data is an increasing limiting resource to complement the current wealth of genomic information. While genomics has been hailed as the discipline to fundamentally change the scope of plant breeding, a more symbiotic relationship is likely to emerge. In the context of developing and evaluating large populations needed for functional genomics, none excel in this area more than plant breeders. While genetic studies have long relied on dedicated, well-structured populations, the resources dedicated to these populations in the context of readily available, inexpensive genotyping is making this philosophy less tractable relative to directly focusing functional genomics on material in breeding programs. Through shifting effort for basic genomic studies from dedicated structured populations, to capturing the entire scope of genetic determinants in breeding lines, we can move towards not only furthering our understanding of functional genomics in plants, but also rapidly improving crops for increased food security, availability and nutrition.

    6. The Future of Microbial Genomics

      SciTech Connect

      Kyrpides, Nikos

      2010-06-02

      Nikos Kyrpides, head of the Genome Biology group at the DOE Joint Genome Institute discusses current challenges in the field of microbial genomics on June 2, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

    7. The UCSC Genome Browser

      PubMed Central

      Karolchik, Donna; Hinrichs, Angie S.; Kent, W. James

      2011-01-01

      The University of California Santa Cruz (UCSC) Genome Browser is a popular Web-based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation “tracks.” The annotations generated by the UCSC Genome Bioinformatics Group and external collaborators include gene predictions, mRNA and expressed sequence tag alignments, simple nucleotide polymorphisms, expression and regulatory data, phenotype and variation data, and pairwise and multiple-species comparative genomics data. All information relevant to a region is presented in one window, facilitating biological analysis and interpretation. The database tables underlying the Genome Browser tracks can be viewed, downloaded, and manipulated using another Web-based application, the UCSC Table Browser. Users can upload personal datasets in a wide variety of formats as custom annotation tracks in both browsers for research or educational purposes. PMID:21975940

    8. AutoGenomics, Inc.

      PubMed

      Vairavan, Ram

      2004-07-01

      AutoGenomics has created an automated multiplexing microarray platform to make genomic and proteomic analyses routine and efficient for clinical and research laboratories. While the emergence of microarrays has advanced genomic analyses, a number of underlying issues, such as cross-hybridization, poor spot morphology and intrinsic fluorescence of the solid substrate, have yet to be fully resolved. Current methods use discrete instrumentation, are manual and require highly skilled labor, which leads to inconsistent results. AutoGenomics' automated platform uses a three-dimensional BioFilmChip microarray to circumvent these issues, providing optimal spot morphology and utilizing solution-based hybridization with allele-specific primer extension to improve single-base discrimination. AutoGenomics is developing applications for the early detection and management of complex disease states in oncology, cardiology, and mental disorders. Customers include clinical reference laboratories, hospitals, academic institutions, and pharmaceutical and biotech companies. Founded in 1999, the company is headquartered in Carlsbad, California, USA.

    9. Microbial Genomes Multiply

      NASA Technical Reports Server (NTRS)

      Doolittle, Russell F.

      2002-01-01

      The publication of the first complete sequence of a bacterial genome in 1995 was a signal event, underscored by the fact that the article has been cited more than 2,100 times during the intervening seven years. It was a marvelous technical achievement, made possible by automatic DNA-sequencing machines. The feat is the more impressive in that complete genome sequencing has now been adopted in many different laboratories around the world. Four years ago in these columns I examined the situation after a dozen microbial genomes had been completed. Now, with upwards of 60 microbial genome sequences determined and twice that many in progress, it seems reasonable to assess just what is being learned. Are new concepts emerging about how cells work? Have there been practical benefits in the fields of medicine and agriculture? Is it feasible to determine the genomic sequence of every bacterial species on Earth? The answers to these questions maybe Yes, Perhaps, and No, respectively.

    10. Comparative genomics of nematodes.

      PubMed

      Mitreva, Makedonka; Blaxter, Mark L; Bird, David M; McCarter, James P

      2005-10-01

      Recent transcriptome and genome projects have dramatically expanded the biological data available across the phylum Nematoda. Here we summarize analyses of these sequences, which have revealed multiple unexpected results. Despite a uniform body plan, nematodes are more diverse at the molecular level than was previously recognized, with many species- and group-specific novel genes. In the genus Caenorhabditis, changes in chromosome arrangement, particularly local inversions, are also rapid, with breakpoints occurring at 50-fold the rate in vertebrates. Tylenchid plant parasitic nematode genomes contain several genes closely related to genes in bacteria, implicating horizontal gene transfer events in the origins of plant parasitism. Functional genomics techniques are also moving from Caenorhabditis elegans to application throughout the phylum. Soon, eight more draft nematode genome sequences will be available. This unique resource will underpin both molecular understanding of these most abundant metazoan organisms and aid in the examination of the dynamics of genome evolution in animals.

    11. Molecular relationships between Australian annual wild rice, Oryza meridionalis, and two related perennial forms

      PubMed Central

      2013-01-01

      Background The perennial, Oryza rufipogon distributed from Asia to Australia and the annual O. meridionalis indigenous to Australia are AA genome species in the Oryza. However, recent research has demonstrated that the Australian AA genome perennial populations have maternal genomes more closely related to those of O. meridionalis than to those found in Asian populations of O. rufipogon suggesting that the Australian perennials may represent a new distinct gene pool for rice. Results Analysis of an Oryza core collection covering AA genome species from Asia to Oceania revealed that some Oceania perennials had organellar genomes closely related to that of O meridionalis (meridionalis-type). O. rufipogon accessions from New Guinea carried either the meridionalis-type or rufirpogon-type (like O. rufipogon) organellar genomes. Australian perennials carried only the meridionalis-type organellar genomes when accompanied by the rufipogon-type nuclear genome. New accessions were collected to better characterize the Australian perennials, and their life histories (annual or perennial) were confirmed by field observations. All of the material collected carried only meridionalis-type organellar genomes. However, there were two distinct perennial groups. One of them carried an rufipogon-type nuclear genome similar to the Australian O. rufipogon in the core collection and the other carried an meridionalis-type nuclear genome not represented in the existing collection. Morphologically the rufipogon-type shared similarity with Asian O. rufipogon. The meridionalis-type showed some similarities to O. meridionalis such as the short anthers usually characteristic of annual populations. However, the meridionalis-type perennial was readily distinguished from O. meridionalis by the presence of a larger lemma and higher number of spikelets. Conclusion Analysis of current accessions clearly indicated that there are two distinct types of Australian perennials. Both of them differed

    12. Fourteenth-Sixteenth Microbial Genomics Conference-2006-2008

      SciTech Connect

      Miller, Jeffrey H

      2011-04-18

      The concept of an annual meeting on the E. coli genome was formulated at the Banbury Center Conference on the Genome of E. coli in October, 1991. The first meeting was held on September 10-14, 1992 at the University of Wisconsin, and this was followed by a yearly series of meetings, and by an expansion to include The fourteenth meeting took place September 24-28, 2006 at Lake Arrowhead, CA, the fifteenth September 16-20, 2007 at the University of Maryland, College Park, MD, and the sixteenth September 14-18, 2008 at Lake Arrowhead. The full program for the 16th meeting is attached. There have been rapid and exciting advances in microbial genomics that now make possible comparing large data sets of sequences from a wide variety of microbial genomes, and from whole microbial communities. Examining the “microbiomes”, the living microbial communities in different host organisms opens up many possibilities for understanding the landscape presented to pathogenic microorganisms. For quite some time there has been a shifting emphasis from pure sequence data to trying to understand how to use that information to solve biological problems. Towards this end new technologies are being developed and improved. Using genetics, functional genomics, and proteomics has been the recent focus of many different laboratories. A key element is the integration of different aspects of microbiology, sequencing technology, analysis techniques, and bioinformatics. The goal of these conference is to provide a regular forum for these interactions to occur. While there have been a number of genome conferences, what distinguishes the Microbial Genomics Conference is its emphasis on bringing together biology and genetics with sequencing and bioinformatics. Also, this conference is the longest continuing meeting, now established as a major regular annual meeting. In addition to its coverage of microbial genomes and biodiversity, the meetings also highlight microbial communities and the use of

    13. Phytozome Comparative Plant Genomics Portal

      SciTech Connect

      Goodstein, David; Batra, Sajeev; Carlson, Joseph; Hayes, Richard; Phillips, Jeremy; Shu, Shengqiang; Schmutz, Jeremy; Rokhsar, Daniel

      2014-09-09

      The Dept. of Energy Joint Genome Institute is a genomics user facility supporting DOE mission science in the areas of Bioenergy, Carbon Cycling, and Biogeochemistry. The Plant Program at the JGI applies genomic, analytical, computational and informatics platforms and methods to: 1. Understand and accelerate the improvement (domestication) of bioenergy crops 2. Characterize and moderate plant response to climate change 3. Use comparative genomics to identify constrained elements and infer gene function 4. Build high quality genomic resource platforms of JGI Plant Flagship genomes for functional and experimental work 5. Expand functional genomic resources for Plant Flagship genomes

    14. Mutation of Breast Cancer Cell Genomic DNA by APOBEC3B

      DTIC Science & Technology

      2012-09-01

      Award Number: W81XWH-11-1-0014 TITLE: Mutation of Breast Cancer Cell Genomic DNA by APOBEC3B...September 2012 2. REPORT TYPE ANNUAL SUMMARY 3. DATES COVERED 01 Sep 2012 – 31 Aug 2012 4. TITLE AND SUBTITLE Mutation of Breast Cancer Cell Genomic...Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Many breast cancers have somatic mutation spectra dominated by C-to

    15. FY 1994 Annual Work Plan

      SciTech Connect

      Not Available

      1993-09-30

      In accordance with the Inspector General`s Strategic Planning Policy directive, the Office of Inspector General (OIG) annually updates its Strategic Plan with budgetary and program guidance for the next fiscal year. The program guidance identifies and establishes priorities for OIG coverage of important DOE issues and operations, provides the basis for assigning OIG resources, and is the source for issues covered in Assistant Inspectors General annual work plans. The Office of the Assistant Inspector General for Audits (AIGA) publishes an Annual Work Plan in September of each year. The plan includes the OIG program guidance and shows the commitment of resources necessary to accomplish the assigned work and meet our goals. The program guidance provides the framework within which the AIGA work will be planned and accomplished. Audits included in this plan are designed to help insure that the requirements of our stakeholders have been considered and blended into a well balanced audit program.

    16. NCBI viral genomes resource.

      PubMed

      Brister, J Rodney; Ako-Adjei, Danso; Bao, Yiming; Blinkova, Olga

      2015-01-01

      Recent technological innovations have ignited an explosion in virus genome sequencing that promises to fundamentally alter our understanding of viral biology and profoundly impact public health policy. Yet, any potential benefits from the billowing cloud of next generation sequence data hinge upon well implemented reference resources that facilitate the identification of sequences, aid in the assembly of sequence reads and provide reference annotation sources. The NCBI Viral Genomes Resource is a reference resource designed to bring order to this sequence shockwave and improve usability of viral sequence data. The resource can be accessed at http://www.ncbi.nlm.nih.gov/genome/viruses/ and catalogs all publicly available virus genome sequences and curates reference genome sequences. As the number of genome sequences has grown, so too have the difficulties in annotating and maintaining reference sequences. The rapid expansion of the viral sequence universe has forced a recalibration of the data model to better provide extant sequence representation and enhanced reference sequence products to serve the needs of the various viral communities. This, in turn, has placed increased emphasis on leveraging the knowledge of individual scientific communities to identify important viral sequences and develop well annotated reference virus genome sets.

    17. The banana genome hub.

      PubMed

      Droc, Gaëtan; Larivière, Delphine; Guignon, Valentin; Yahiaoui, Nabila; This, Dominique; Garsmeur, Olivier; Dereeper, Alexis; Hamelin, Chantal; Argout, Xavier; Dufayard, Jean-François; Lengelle, Juliette; Baurens, Franc-Christophe; Cenci, Alberto; Pitollat, Bertrand; D'Hont, Angélique; Ruiz, Manuel; Rouard, Mathieu; Bocs, Stéphanie

      2013-01-01

      Banana is one of the world's favorite fruits and one of the most important crops for developing countries. The banana reference genome sequence (Musa acuminata) was recently released. Given the taxonomic position of Musa, the completed genomic sequence has particular comparative value to provide fresh insights about the evolution of the monocotyledons. The study of the banana genome has been enhanced by a number of tools and resources that allows harnessing its sequence. First, we set up essential tools such as a Community Annotation System, phylogenomics resources and metabolic pathways. Then, to support post-genomic efforts, we improved banana existing systems (e.g. web front end, query builder), we integrated available Musa data into generic systems (e.g. markers and genetic maps, synteny blocks), we have made interoperable with the banana hub, other existing systems containing Musa data (e.g. transcriptomics, rice reference genome, workflow manager) and finally, we generated new results from sequence analyses (e.g. SNP and polymorphism analysis). Several uses cases illustrate how the Banana Genome Hub can be used to study gene families. Overall, with this collaborative effort, we discuss the importance of the interoperability toward data integration between existing information systems. Database URL: http://banana-genome.cirad.fr/

    18. Genomic Insights into Bifidobacteria

      PubMed Central

      Lee, Ju-Hoon; O'Sullivan, Daniel J.

      2010-01-01

      Summary: Since the discovery in 1899 of bifidobacteria as numerically dominant microbes in the feces of breast-fed infants, there have been numerous studies addressing their role in modulating gut microflora as well as their other potential health benefits. Because of this, they are frequently incorporated into foods as probiotic cultures. An understanding of their full interactions with intestinal microbes and the host is needed to scientifically validate any health benefits they may afford. Recently, the genome sequences of nine strains representing four species of Bifidobacterium became available. A comparative genome analysis of these genomes reveals a likely efficient capacity to adapt to their habitats, with B. longum subsp. infantis exhibiting more genomic potential to utilize human milk oligosaccharides, consistent with its habitat in the infant gut. Conversely, B. longum subsp. longum exhibits a higher genomic potential for utilization of plant-derived complex carbohydrates and polyols, consistent with its habitat in an adult gut. An intriguing observation is the loss of much of this genome potential when strains are adapted to pure culture environments, as highlighted by the genomes of B. animalis subsp. lactis strains, which exhibit the least potential for a gut habitat and are believed to have evolved from the B. animalis species during adaptation to dairy fermentation environments. PMID:20805404

    19. Swine Genome Sequencing Consortium (SGSC): A Strategic Roadmap for Sequencing The Pig Genome

      PubMed Central

      Schook, Lawrence B.; Beever, Jonathan E.; Rogers, Jane; Humphray, Sean; Archibald, Alan; Chardon, Patrick; Milan, Denis; Rohrer, Gary; Eversole, Kellye

      2005-01-01

      The Swine Genome Sequencing Consortium (SGSC) was formed in September 2003 by academic, government and industry representatives to provide international coordination for sequencing the pig genome. The SGSC’s mission is to advance biomedical research for animal production and health by the development of DNAbased tools and products resulting from the sequencing of the swine genome. During the past 2 years, the SGSC has met bi-annually to develop a strategic roadmap for creating the required scientific resources, to integrate existing physical maps, and to create a sequencing strategy that captured international participation and a broad funding base. During the past year, SGSC members have integrated their respective physical mapping data with the goal of creating a minimal tiling path (MTP) that will be used as the sequencing template. During the recent Plant and Animal Genome meeting (January 16, 2005 San Diego, CA), presentations demonstrated that a human–pig comparative map has been completed, BAC fingerprint contigs (FPC) for each of the autosomes and X chromosome have been constructed and that BAC end-sequencing has permitted, through BLAST analysis and RH-mapping, anchoring of the contigs. Thus, significant progress has been made towards the creation of a MTP. In addition, whole-genome (WG) shotgun libraries have been constructed and are currently being sequenced in various laboratories around the globe. Thus, a hybrid sequencing approach in which 3x coverage of BACs comprising the MTP and 3x of the WG-shotgun libraries will be used to develop a draft 6x coverage of the pig genome. PMID:18629187

    20. LLNL NESHAP's 1999 Annual Report

      SciTech Connect

      Gallegos, G.; Biermann, A.H.; Harrach, R.J.; Bertoldo, N.A.; Berger, R.L.; Surano,K.A.

      2000-06-01

      This annual report is prepared pursuant to the National Emissions Standards for Hazardous Air Pollutants (NESHAPs) 40 CFR Part 61, Subpart H; Subpart H governs radionuclide emissions to air from Department of Energy (DOE) facilities. NESHAPs limits the emission of radionuclides to the ambient air from DOE facilities to levels resulting in an annual effective dose equivalent (EDE) of 10 mrem (100 {micro}Sv) to any member of the public. The EDEs for the Lawrence Livermore National Laboratory (LLNL) site-wide maximally exposed members of the public from 1999 operations are summarized.


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